Gene ID NCBI Gene ID Gene Symbol Type Ctr1 Read Count Ctr2 Read Count Ctr3 Read Count Ctr1 FPKM Ctr2 FPKM Ctr3 FPKM IDPN1 FPKM IDPN2 FPKM IDPN3 FPKM Ctr Average FPKM IDPN Average FPKM IDPN1 Read Count IDPN2 Read Count IDPN3 Read Count Ctr Average Read Count IDPN Average Read Count Qvalue (IDPN / Ctr) log2 (IDPN / Ctr) KEGG Pathway Desc GO_C Desc GO_F Desc GO_P Desc 100009600 100009600 'Zglp1' mRNA 11 3 1 0.69 0.19 0.07 0.06 0.28 0.11 0.316666667 0.15 1 5 2 5 2.666666667 0.608596619 -0.886973403 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis+++GO:0048599///oocyte development" 100017 100017 'Ldlrap1' mRNA 920 845 797 16.16 14.51 14.68 18.38 18.73 17.49 15.11666667 18.2 1157 1110 1051 854 1106 9.45E-05 0.362159423 04144///Endocytosis+++04979///Cholesterol metabolism GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005883///neurofilament+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0030424///axon+++GO:0055037///recycling endosome "GO:0001540///amyloid-beta binding+++GO:0001784///phosphotyrosine residue binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030276///clathrin binding+++GO:0035591///signaling adaptor activity+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0035650///AP-1 adaptor complex binding+++GO:0050750///low-density lipoprotein particle receptor binding" GO:0006629///lipid metabolic process+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0031623///receptor internalization+++GO:0034383///low-density lipoprotein particle clearance+++GO:0042632///cholesterol homeostasis+++GO:0042982///amyloid precursor protein metabolic process+++GO:0043393///regulation of protein binding+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0071345///cellular response to cytokine stimulus+++GO:0090118///receptor-mediated endocytosis involved in cholesterol transport+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905581///positive regulation of low-density lipoprotein particle clearance+++GO:1905602///positive regulation of receptor-mediated endocytosis involved in cholesterol transport 100019 100019 'Mdn1' mRNA 421 395 392 1.2 1.1 1.18 1.12 0.99 1.08 1.16 1.063333333 454 392 425 402.6666667 423.6666667 0.729739811 0.06059691 03008///Ribosome biogenesis in eukaryotes "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0030687///preribosome, large subunit precursor+++GO:0045111///intermediate filament cytoskeleton" GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0000027///ribosomal large subunit assembly+++GO:0006364///rRNA processing 100033459 100033459 'Ifi208' mRNA 16.72 14 16.78 0.27 0.2 0.29 1.66 1.86 1.76 0.253333333 1.76 114.61 118.68 110.76 15.83333333 114.6833333 8.85E-17 2.882184213 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0035458///cellular response to interferon-beta 100034251 100034251 'Wfdc17' mRNA 143 155 143 27 29.33 28.67 694.47 750.93 736.53 28.33333333 727.31 4176 4377 4257 147 4270 0 4.850112791 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 100034361 100034361 'Mfap1b' mRNA 1860.07 1755.7 1759.21 56.49 52.54 56.68 37.15 39.62 36.63 55.23666667 37.8 1406.13 1463.62 1341.78 1791.66 1403.843333 7.11E-06 -0.36396086 GO:0001527///microfibril+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0005813///centrosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0071005///U2-type precatalytic spliceosome GO:0005201///extracellular matrix structural constituent "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 100034363 100034363 'Tmsb15b2' mRNA 21.96 35.95 24.37 2.33 3.79 2.74 1.09 0.89 1.38 2.953333333 1.12 11.72 9.35 14.37 27.42666667 11.81333333 0.042830105 -1.242618896 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0003785///actin monomer binding GO:0007015///actin filament organization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0042989///sequestering of actin monomers+++GO:0051497///negative regulation of stress fiber assembly 100034684 100034684 'Cstdc5' mRNA 4 8 8.88 0.84 1.69 1.98 1.3 1.5 0.77 1.503333333 1.19 7 7.85 4 6.96 6.283333333 0.890404347 -0.169562063 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 100034748 100034748 'A930017K11Rik' mRNA 4 2 0 0.1 0.05 0 0.06 0.02 0.02 0.05 0.033333333 3 1 1 2 1.666666667 0.916736899 -0.256738601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100036521 100036521 'Umad1' mRNA 641 683 700 16.63 17.46 19.26 10.19 9.93 12.26 17.78333333 10.79333333 452 430 526 674.6666667 469.3333333 1.81E-05 -0.537117387 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100037258 100037258 'Dnajc3' mRNA 3697 3776 3690 38 38.16 40.23 41.49 39.64 41.58 38.79666667 40.90333333 4647 4338 4511 3721 4498.666667 1.69E-05 0.261082722 04141///Protein processing in endoplasmic reticulum+++05164///Influenza A GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding GO:0006417///regulation of translation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006986///response to unfolded protein+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036494///positive regulation of translation initiation in response to endoplasmic reticulum stress+++GO:0043066///negative regulation of apoptotic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070417///cellular response to cold+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 100037278 100037278 'Niban3' mRNA 96.7 81.09 73.79 2.08 1.63 1.61 1.8 1.51 1.58 1.773333333 1.63 109.1 96.55 91.09 83.86 98.91333333 0.455823224 0.233473066 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100037282 100037282 'Rsph3b' mRNA 590.38 621.31 560.51 21.39 22.19 21.54 11.54 12.93 11.41 21.70666667 11.96 365.95 400.1 350.05 590.7333333 372.0333333 2.14E-08 -0.677478241 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 100037283 100037283 'Rnaset2a' mRNA 4807.36 5007.91 4721.52 316.22 325.97 329.75 504.58 519.16 497.99 323.98 507.2433333 8788.94 8809.19 8377.29 4845.596667 8658.473333 2.04E-52 0.826040465 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016021///integral component of membrane+++GO:0043202///lysosomal lumen GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0033897///ribonuclease T2 activity "GO:0002376///immune system process+++GO:0006401///RNA catabolic process+++GO:0045087///innate immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 100038347 100038347 'Fam174b' mRNA 2413 2617 2552 49.92 53.29 56 66.52 63.73 64.23 53.07 64.82666667 3699 3461 3458 2527.333333 3539.333333 3.82E-12 0.472624592 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007030///Golgi organization 100038417 100038417 'Spink13' mRNA 4 3 4 0.23 0.17 0.23 0 0 0 0.21 0 0 0 0 3.666666667 0 0.053943656 -4.333804075 GO:0005576///extracellular region GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:1902225///negative regulation of acrosome reaction 100038489 100038489 'Apela' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction+++04371///Apelin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031704///apelin receptor binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0007509///mesoderm migration involved in gastrulation+++GO:0030154///cell differentiation+++GO:0035050///embryonic heart tube development+++GO:0045766///positive regulation of angiogenesis+++GO:0045823///positive regulation of heart contraction+++GO:0060183///apelin receptor signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060674///placenta blood vessel development+++GO:0060976///coronary vasculature development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090133///mesendoderm migration+++GO:0090134///cell migration involved in mesendoderm migration+++GO:1901165///positive regulation of trophoblast cell migration+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1904022///positive regulation of G protein-coupled receptor internalization 100038514 100038514 'Gm11837' mRNA 65.21 63.65 47.25 4.79 4.63 3.68 0.93 1.9 1.27 4.366666667 1.366666667 14.46 28.83 19.15 58.70333333 20.81333333 3.93E-04 -1.522152904 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100038538 100038538 'Gm10767' mRNA 44.27 25.06 35.1 1.56 0.87 1.31 0.77 0.45 0.67 1.246666667 0.63 25.05 14.45 21.05 34.81 20.18333333 0.131974798 -0.811624237 GO:0005575///cellular_component+++GO:0005845///mRNA cap binding complex GO:0003674///molecular_function+++GO:0003723///RNA binding GO:0008150///biological_process+++GO:0106005///RNA 5'-cap (guanine-N7)-methylation 100038570 100038570 'Prcd' mRNA 26 28 27 1.43 1.72 1.96 0.22 0.38 0.46 1.703333333 0.353333333 3 7 7 27 5.666666667 8.02E-04 -2.260573633 GO:0001750///photoreceptor outer segment+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection GO:0002046///opsin binding GO:0007601///visual perception+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception 100038725 100038725 'Cep85l' mRNA 883 892 498 6.38 6.34 3.84 1.55 1.9 1.62 5.52 1.69 248 297 252 757.6666667 265.6666667 2.31E-18 -1.509982091 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0001764///neuron migration 100038847 100038847 'Gm10406' mRNA 17.02 10.99 17.05 0.46 0.3 0.5 0.37 0.19 0.45 0.42 0.336666667 16.09 8.08 17.61 15.02 13.92666667 0.884842725 -0.124128575 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100038854 100038854 'Cstdc6' mRNA 0 0 1 0 0 0.29 0 0.28 0.25 0.096666667 0.176666667 0 1.15 1 0.333333333 0.716666667 0.863090843 0.898087804 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 100038862 100038862 'Btnl1' mRNA 0 0 1 0 0 0.03 0 0 0.02 0.01 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0045062///extrathymic T cell selection+++GO:0050852///T cell receptor signaling pathway 100038882 100038882 'Isg15' mRNA 604 580 442 55.48 52.85 43.09 135.78 141.21 134.44 50.47333333 137.1433333 1691 1712 1616 542 1673 4.46E-62 1.61944673 04622///RIG-I-like receptor signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0022627///cytosolic small ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding GO:0007229///integrin-mediated signaling pathway+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0030501///positive regulation of bone mineralization+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032020///ISG15-protein conjugation+++GO:0032461///positive regulation of protein oligomerization+++GO:0032649///regulation of interferon-gamma production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0034340///response to type I interferon+++GO:0042742///defense response to bacterium+++GO:0045071///negative regulation of viral genome replication+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0051607///defense response to virus+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0070585///protein localization to mitochondrion 100038909 100038909 'Gm14548' mRNA 48.74 65.88 40.25 1.46 1.96 1.17 15.02 16.14 14.11 1.53 15.09 618.17 638.12 555.29 51.62333333 603.86 2.59E-86 3.557773394 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005886///plasma membrane GO:0032396///inhibitory MHC class I receptor activity GO:0019221///cytokine-mediated signaling pathway 100038927 100038927 'Defa30' mRNA 1 0 0 0.27 0 0 0 0 0 0.09 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04621///NOD-like receptor signaling pathway+++05150///Staphylococcus aureus infection+++05202///Transcriptional misregulation in cancer GO:0005615///extracellular space+++GO:0030496///midbody+++GO:0043231///intracellular membrane-bounded organelle GO:0042803///protein homodimerization activity GO:0002227///innate immune response in mucosa+++GO:0019731///antibacterial humoral response+++GO:0031640///killing of cells of other organism+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051673///membrane disruption in other organism+++GO:0051873///killing by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:1905710///positive regulation of membrane permeability 100038947 100038947 'Sirpb1c' mRNA 13.21 9.54 21.91 0.76 0.38 0.95 19.22 17.45 17.43 0.696666667 18.03333333 538.96 476.14 466.78 14.88666667 493.96 9.21E-80 5.089381107 04380///Osteoclast differentiation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0035556///intracellular signal transduction+++GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation 100038949 100038949 'Gm1979' mRNA 11.08 22.71 17.53 0.33 0.67 0.56 0.05 0.03 0.03 0.52 0.036666667 1.54 1 1.07 17.10666667 1.203333333 5.31E-04 -4.070237361 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100038992 100038992 'Gm2001' mRNA 0 0 1 0 0 1.03 0.87 0 0 0.343333333 0.29 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 04212///Longevity regulating pathway - worm GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0031386///protein tag "GO:0000398///mRNA splicing, via spliceosome+++GO:0006464///cellular protein modification process+++GO:0008150///biological_process" 100039029 100039029 'LOC100039029' mRNA 2.78 1.3 0 0.56 0.26 0 0 0.58 0.32 0.273333333 0.3 0 3.18 1.74 1.36 1.64 0.88265652 0.447329987 100039045 100039045 'Gm10471' mRNA 40.23 39.1 35.15 0.66 0.63 0.61 0.02 0.04 0.08 0.633333333 0.046666667 1.26 3 5.43 38.16 3.23 2.11E-07 -3.669996468 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100039060 100039060 'Gm2026' mRNA 1088.2 1077.12 1040.15 14.55 14.19 14.95 14.35 13.28 13.91 14.56333333 13.84666667 1231.03 1121.43 1163.5 1068.49 1171.986667 0.201339932 0.120932083 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 100039123 100039123 'Gm14295' mRNA 1022.53 1087.36 948.86 18.11 20.28 17.8 16.94 15.74 17.19 18.73 16.62333333 829.29 775.55 746.32 1019.583333 783.72 2.56E-05 -0.389985735 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 100039139 100039139 'Ccdc152' mRNA 19.75 15.78 20.68 1.29 1.07 1.51 3.29 3.41 3.54 1.29 3.413333333 57.9 55.34 57.96 18.73666667 57.06666667 1.02E-04 1.630873857 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100039210 100039210 'Gm2102' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100039239 100039239 'Gm2115' mRNA 187 186 199 2.11 2.07 2.38 2.65 2.74 2.92 2.186666667 2.77 270 273 288 190.6666667 277 0.002114517 0.525608988 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100039252 100039252 'Gm12693' mRNA 7.55 6.14 8.62 0.28 0.22 0.33 0.12 0.35 0.16 0.276666667 0.21 3.64 10.89 4.99 7.436666667 6.506666667 0.821114198 -0.313629428 100039269 100039269 'Gm2128' mRNA 0 0 1 0 0 0.02 0 0.02 0 0.006666667 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 100039284 100039284 'Gm2137' mRNA 67.17 51.31 37.92 3.32 2.5 1.99 1.26 1.04 1.52 2.603333333 1.273333333 29.21 23.64 34.22 52.13333333 29.02333333 0.048538405 -0.854766589 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100039350 100039350 'Gm16500' mRNA 21.97 13.06 18.96 2.09 1.23 1.92 1.42 1.2 0.61 1.746666667 1.076666667 17.06 14.06 7.01 17.99666667 12.71 0.56394486 -0.470311206 100039441 100039441 'Gm2237' mRNA 5.72 14.2 5.03 0.19 0.53 0.26 0.19 0.14 0.37 0.326666667 0.233333333 8.3 7.56 11.15 8.316666667 9.003333333 0.918345722 0.117595785 100039532 100039532 'Gm10029' mRNA 184.67 178.16 206.22 39.33 38.12 46.65 45.12 64.81 61.17 41.36666667 57.03333333 240.03 333.95 312.56 189.6833333 295.5133333 0.001207175 0.627559028 100039596 100039596 'Tcf24' mRNA 11 14 5 0.15 0.19 0.07 0.06 0.09 0 0.136666667 0.05 5 7 0 10 4 0.275841699 -1.315227265 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032502///developmental process 100039672 100039672 'Msmp' mRNA 0.39 1.57 1.47 0.04 0.15 0.15 0.25 0.15 0.92 0.113333333 0.44 3.06 1.81 10.82 1.143333333 5.23 0.160080889 2.789179719 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0031727///CCR2 chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0048247///lymphocyte chemotaxis 100039674 100039674 'Gm10634' mRNA 7.41 2.73 1 0.16 0.05 0.03 0.19 0.07 0.12 0.08 0.126666667 8.99 3 4.82 3.713333333 5.603333333 0.733225368 0.580678143 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100039681 100039681 'Zcwpw2' mRNA 26.56 24.28 18.9 0.68 0.61 0.51 0.43 0.39 0.4 0.6 0.406666667 19.13 17.16 17.58 23.24666667 17.95666667 0.588067243 -0.366613691 GO:0005634///nucleus GO:0004386///helicase activity+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding GO:0008150///biological_process 100039707 100039707 'Mthfsl' mRNA 960.18 936.56 786.16 42.79 40.66 43.38 63.18 60.71 59.32 42.27666667 61.07 1094.72 1030.73 983.37 894.3 1036.273333 0.042151105 0.203128884 00670///One carbon pool by folate GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005542///folic acid binding+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding GO:0009396///folic acid-containing compound biosynthetic process+++GO:0035999///tetrahydrofolate interconversion 100039781 100039781 'Hrct1' mRNA 62 59 80 4.45 4.19 6.09 10.08 10.47 9.46 4.91 10.00333333 161 163 146 67 156.6666667 1.28E-06 1.207979598 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100039786 100039786 'Gm2423' mRNA 2481.22 2502.66 2525.41 99.58 99.08 107.53 114.62 122.58 112.15 102.0633333 116.45 3280.51 3422.98 3105.1 2503.096667 3269.53 3.09E-07 0.37285504 100039789 100039789 'Gm12407' mRNA 47.26 57.52 52.43 5.1 6.17 6 2.65 2.71 3.17 5.756666667 2.843333333 28.09 27.88 32.33 52.40333333 29.43333333 0.035171773 -0.854210432 100039794 100039794 'Gm2427' mRNA 2.57 0 6.67 0.14 0 0.39 0.5 0.54 0.68 0.176666667 0.573333333 10.38 10.95 13.75 3.08 11.69333333 0.083639133 2.002233916 100039795 100039795 'Ildr2' mRNA 221 197 141 1.47 1.28 1.01 3.34 2.97 3.07 1.253333333 3.126666667 560 496 508 186.3333333 521.3333333 3.92E-22 1.477718022 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0009749///response to glucose+++GO:0030073///insulin secretion+++GO:0030154///cell differentiation+++GO:0031016///pancreas development+++GO:0048873///homeostasis of number of cells within a tissue 100039796 100039796 'Tgtp2' mRNA 443.25 491.6 433.66 8.69 9.48 9.01 19.93 23.36 22.03 9.06 21.77333333 1169.97 1339.31 1252.43 456.17 1253.903333 9.84E-46 1.450589924 GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0045087///innate immune response 100039815 100039815 'Gm2436' mRNA 15.34 3.14 6.28 0.52 0.11 0.23 0.17 0.05 0.21 0.286666667 0.143333333 5.58 1.57 6.93 8.253333333 4.693333333 0.437864513 -1.014278077 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection 100039830 100039830 'Gm2446' mRNA 15.34 3.14 6.28 0.52 0.11 0.23 0.17 0.05 0.21 0.286666667 0.143333333 5.58 1.57 6.93 8.253333333 4.693333333 0.437864513 -1.014278077 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection 100039863 100039863 'Gm13306' mRNA 266.25 261.1 219.38 8.96 8.24 7.33 3.72 3.49 3.73 8.176666667 3.646666667 135.87 124.2 131.69 248.91 130.5866667 1.80E-07 -0.944793897 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity GO:0006955///immune response+++GO:0008150///biological_process+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0060326///cell chemotaxis+++GO:2000251///positive regulation of actin cytoskeleton reorganization 100039946 100039946 'Siglecl1' mRNA 1 2 0 0.2 0.14 0 0.2 0 0.07 0.113333333 0.09 2 0 1 1 1 0.998696207 0.005940359 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100039968 100039968 'Tmem35b' mRNA 378 397 358 20.6 21.37 20.7 19.38 20.85 20.54 20.89 20.25666667 408 428 418 377.6666667 418 0.364916141 0.136296696 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100040018 100040018 'Gmfg-ps' mRNA 3.35 0 3.45 0.45 0 0.5 1.57 4.01 2.68 0.316666667 2.753333333 13.23 32.78 21.74 2.266666667 22.58333333 2.90E-04 3.445945014 100040031 100040031 'Gm20823' mRNA 0.5 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.166666667 0 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 100040048 100040048 'Ccl27b' mRNA 274.8 263.36 332.95 5.97 5.59 6.97 2.8 2.88 2.45 6.176666667 2.71 145.07 148.21 105.82 290.37 133.0333333 1.64E-08 -1.144764083 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031728///CCR3 chemokine receptor binding GO:0006955///immune response+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:2000251///positive regulation of actin cytoskeleton reorganization 100040049 100040049 'Smim38' mRNA 1 1 0 0.07 0.07 0 0.06 0.13 0.06 0.046666667 0.083333333 1 2 1 0.666666667 1.333333333 0.750387006 1.018771784 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100040248 100040248 'Gm11563' mRNA 0 0 1 0 0 0.07 0.11 0 0 0.023333333 0.036666667 2 0 0 0.333333333 0.666666667 0.863090843 0.855344965 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 100040268 100040268 'Olfr157' mRNA 0 0 2 0 0 0.07 0 0 0.03 0.023333333 0.01 0 0 1 0.666666667 0.333333333 0.863090843 -0.975320503 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 100040298 100040298 'Gm15501' mRNA 62.77 64.1 61.79 5.32 5.28 5.39 8.93 6.65 8.31 5.33 7.963333333 117.48 94.54 104.04 62.88666667 105.3533333 0.007879787 0.739172434 03010///Ribosome+++05171///Coronavirus disease - COVID-19 100040416 100040416 'Rpl13-ps6' mRNA 42.62 43.94 66.42 4.02 4.11 6.64 6.85 5.55 5.04 4.923333333 5.813333333 83.14 65.62 59 50.99333333 69.25333333 0.275811423 0.43081402 100040462 100040462 'Mndal' mRNA 110.55 96.57 90.46 2.18 2.06 1.96 14.98 15.51 13.44 2.066666667 14.64333333 727.71 709.01 622.31 99.19333333 686.3433333 8.10E-79 2.786974396 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0009617///response to bacterium+++GO:0030308///negative regulation of cell growth+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0040008///regulation of growth 100040500 100040500 'Gm2808' mRNA 23.94 22.63 14.9 0.21 0.2 0.14 0.05 0.05 0.1 0.183333333 0.066666667 6.42 6.67 11.98 20.49 8.356666667 0.063655214 -1.361073152 100040531 100040531 'Dynlt1f' mRNA 553.39 537.56 586.26 46.58 44.82 52.33 57.22 66.26 56.12 47.91 59.86666667 780.24 879.01 738.75 559.07 799.3333333 2.77E-05 0.503032755 05132///Salmonella infection GO:0001917///photoreceptor inner segment+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005868///cytoplasmic dynein complex+++GO:0005881///cytoplasmic microtubule+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0099503///secretory vesicle GO:0008022///protein C-terminus binding+++GO:0030742///GTP-dependent protein binding+++GO:0031681///G-protein beta-subunit binding+++GO:0042802///identical protein binding GO:0000132///establishment of mitotic spindle orientation+++GO:0008150///biological_process+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0050768///negative regulation of neurogenesis+++GO:0051301///cell division+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 100040545 100040545 'Gm2832' mRNA 2 3.19 3 0.08 0.13 0.13 0.08 0 0.04 0.113333333 0.04 3 0 1 2.73 1.333333333 0.652003492 -1.031071835 100040563 100040563 'Dynlt1c' mRNA 1011.32 930.25 835.73 103.14 95.02 91.04 133.47 132.54 121.81 96.4 129.2733333 1484.83 1434.36 1312.12 925.7666667 1410.436667 2.10E-11 0.597778567 05132///Salmonella infection GO:0001917///photoreceptor inner segment+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005868///cytoplasmic dynein complex+++GO:0005881///cytoplasmic microtubule+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0099503///secretory vesicle GO:0008022///protein C-terminus binding+++GO:0030742///GTP-dependent protein binding+++GO:0031681///G-protein beta-subunit binding+++GO:0042802///identical protein binding GO:0000132///establishment of mitotic spindle orientation+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0016358///dendrite development+++GO:0019060///intracellular transport of viral protein in host cell+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0043087///regulation of GTPase activity+++GO:0048812///neuron projection morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0051301///cell division+++GO:0051493///regulation of cytoskeleton organization+++GO:0060548///negative regulation of cell death+++GO:0061564///axon development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 100040591 100040591 'Kcnj13' mRNA 1498 1575 1535.01 25.97 27.01 28.18 8.73 10.11 9.29 27.05333333 9.376666667 581.95 654.18 604 1536.003333 613.3766667 2.63E-47 -1.336689936 04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 100040599 100040599 'Gm15319' mRNA 9.8 7.46 14.68 0.22 0.16 0.34 0.06 0 0.09 0.24 0.05 3.06 0 4.31 10.64666667 2.456666667 0.074035327 -2.132178705 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100040608 100040608 'Fancf' mRNA 84.54 80.94 28 2.9 2.74 1.02 0.66 0.77 1.1 2.22 0.843333333 22 25 35.7 64.49333333 27.56666667 0.008712751 -1.218374397 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043240///Fanconi anaemia nuclear complex GO:0061630///ubiquitin protein ligase activity GO:0001541///ovarian follicle development+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0036297///interstrand cross-link repair 100040671 100040671 'Gm2897' mRNA 13.66 5 11.29 0.95 0.38 0.63 0.49 0.41 0.28 0.653333333 0.393333333 12.68 5.94 6.53 9.983333333 8.383333333 0.753163157 -0.360809688 100040714 100040714 'Gm20851' mRNA 0 0 0.5 0 0 0.05 0 0.01 0.11 0.016666667 0.04 0 0.09 1.21 0.166666667 0.433333333 0.863090843 0.950016071 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 100040766 100040766 'Mroh2a' mRNA 0 1 2.09 0 0.01 0.03 0.02 0.04 0.04 0.013333333 0.033333333 2 4 3.06 1.03 3.02 0.469736406 1.557220922 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100040807 100040807 'Gm2977' mRNA 0 1.43 0 0 0.05 0 0 0 0.04 0.016666667 0.013333333 0 0 1.32 0.476666667 0.44 0.998591786 -0.011756601 100040843 100040843 'Cyp4a32' mRNA 0 0 8 0 0 0.28 0 0 0 0.093333333 0 0 0 0 2.666666667 0 0.214861191 -3.943741508 00071///Fatty acid degradation+++00590///Arachidonic acid metabolism+++00830///Retinol metabolism+++03320///PPAR signaling pathway+++04270///Vascular smooth muscle contraction+++04750///Inflammatory mediator regulation of TRP channels GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0018685///alkane 1-monooxygenase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050051///leukotriene-B4 20-monooxygenase activity+++GO:0102116///laurate hydroxylase activity+++GO:0103002///16-hydroxypalmitate dehydrogenase activity" GO:0001822///kidney development+++GO:0019369///arachidonic acid metabolic process+++GO:0036101///leukotriene B4 catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0046456///icosanoid biosynthetic process+++GO:0048252///lauric acid metabolic process 100040870 100040870 'Gm3005' mRNA 1.83 2.93 2.03 0.05 0.09 0.06 0.13 0.12 0.14 0.066666667 0.13 5.75 4.78 5.17 2.263333333 5.233333333 0.358761317 1.468738233 100040935 100040935 'Gm3050' mRNA 0 1.43 0 0 0.05 0 0 0 0.04 0.016666667 0.013333333 0 0 1.32 0.476666667 0.44 0.998591786 -0.011756601 100040944 100040944 'Gm3055' mRNA 38.61 57.05 82.62 0.52 0.74 1.18 0.19 0.56 0.12 0.813333333 0.29 16.62 47.28 9.95 59.42666667 24.61666667 0.020091996 -1.314983105 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 100040961 100040961 'Gm10145' mRNA 2.26 0 0 0.23 0 0 0 0 0 0.076666667 0 0 0 0 0.753333333 0 0.749855753 -1.843955659 100040972 100040972 'Tceal7' mRNA 9 2 1 0.6 0.13 0.07 0.06 0 0.42 0.266666667 0.16 1 0 7 4 2.666666667 0.788966975 -0.575175996 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0050699///WW domain binding "GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated" 100041012 100041012 'Gm3095' mRNA 2.1 2.99 2.06 0.05 0.07 0.05 0.06 0.02 0.04 0.056666667 0.04 3.1 1.08 2 2.383333333 2.06 0.998591786 -0.019402752 100041054 100041054 'Gm3115' mRNA 0 1 2 0 0.1 0.21 0 0 0 0.103333333 0 0 0 0 1 0 0.596502362 -2.487866303 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100041057 100041057 'LOC100041057' mRNA 1.33 1.23 0.06 0.03 0.03 0 0.32 0.19 0.32 0.02 0.276666667 14.28 7.86 13.56 0.873333333 11.9 0.005287198 4.081701986 100041077 100041077 'Gm13102' mRNA 0 0 0.5 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.166666667 0 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 100041121 100041121 'Gm10144' mRNA 0 1 1 0 0.06 0.06 0 0.05 0 0.04 0.016666667 0 1 0 0.666666667 0.333333333 0.861179337 -0.920394634 100041146 100041146 'Gm15448' mRNA 7.03 13.64 15.98 0.22 0.43 0.54 2.41 2.72 2.36 0.396666667 2.496666667 90.03 101.39 85.41 12.21666667 92.27666667 2.52E-13 2.964522824 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005886///plasma membrane GO:0032396///inhibitory MHC class I receptor activity GO:0019221///cytokine-mediated signaling pathway 100041151 100041151 'Gm3636' mRNA 29.62 28.21 28.37 0.67 0.59 0.66 0.4 0.63 0.36 0.64 0.463333333 24.03 30.61 16.66 28.73333333 23.76666667 0.645407359 -0.291049576 100041194 100041194 'Ahnak2' mRNA 174 157 204 0.8 0.71 1 3.38 3.11 3.27 0.836666667 3.253333333 843 757 789 178.3333333 796.3333333 1.81E-55 2.141981691 05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0043484///regulation of RNA splicing 100041223 100041223 'Gm20865' mRNA 0 1 0 0 0.08 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 100041230 100041230 'H4c17' mRNA 0 2.43 0 0 0.6 0 0 0 0.55 0.2 0.183333333 0 0 2.44 0.81 0.813333333 0.998591786 0.035579107 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 100041262 100041262 'Gm3239' mRNA 3.82 8.31 6.72 0.09 0.19 0.17 0.14 0.09 0.32 0.15 0.183333333 7 4.33 15.28 6.283333333 8.87 0.624222523 0.60083308 100041273 100041273 'Ndufb4c' mRNA 167.39 230.64 263.75 29.85 41.18 49.94 36.74 41.12 44.88 40.32333333 40.91333333 234.08 254.09 275 220.5933333 254.39 0.426628268 0.19203838 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy 100041283 100041283 'Gm3252' mRNA 8.97 3.91 1.31 0.57 0.23 0.04 0 0.15 0.18 0.28 0.11 0 5.47 4.5 4.73 3.323333333 0.856148336 -0.392292649 100041294 100041294 'Supt4b' mRNA 10.64 3.85 5.99 1.06 0.38 0.64 0.36 0.21 0.59 0.693333333 0.386666667 4.14 2.31 6.52 6.826666667 4.323333333 0.684464855 -0.597502091 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032044///DSIF complex GO:0000993///RNA polymerase II complex binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006397///mRNA processing+++GO:0032785///negative regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II" 100041306 100041306 'Gm3264' mRNA 10.61 6.77 15.28 0.3 0.19 0.46 0.56 0.35 0.34 0.316666667 0.416666667 20.33 13.67 13.4 10.88666667 15.8 0.535587923 0.539084853 100041352 100041352 'Tcp10c' mRNA 3.7 4.35 2.1 0.08 0.09 0.05 0 0.03 0.03 0.073333333 0.02 0 1.23 1.09 3.383333333 0.773333333 0.331025001 -2.161757417 GO:0005634///nucleus+++GO:0005814///centriole GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association "GO:0045892///negative regulation of transcription, DNA-templated" 100041379 100041379 'Zfp980' mRNA 2.23 1.76 0 0.03 0.02 0 0.06 0.01 0.02 0.016666667 0.03 5.21 1.02 1.49 1.33 2.573333333 0.63219558 1.218329008 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100041420 100041420 'Gm3325' mRNA 125.79 139.2 124.57 1.5 1.63 1.53 1.11 0.72 0.84 1.553333333 0.89 115 82.57 93.68 129.8533333 97.08333333 0.092044634 -0.433325366 100041433 100041433 'Zfp981' mRNA 3 6.65 1.01 0.05 0.12 0.02 0.03 0.05 0.02 0.063333333 0.033333333 2.09 2.93 1.01 3.553333333 2.01 0.61710725 -0.988226616 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100041449 100041449 'Cyp3a59' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005496///steroid binding+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0050649///testosterone 6-beta-hydroxylase activity+++GO:0070330///aromatase activity+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0008202///steroid metabolic process+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0070989///oxidative demethylation 100041488 100041488 'Gm11937' mRNA 3 0 0 0.35 0 0 0 0 0 0.116666667 0 0 0 0 1 0 0.653555534 -2.427804616 GO:0005575///cellular_component+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 100041505 100041505 'Gm3376' mRNA 0 0 0.11 0 0 0 0 0.2 0.01 0 0.07 0 6 0.29 0.036666667 2.096666667 0.348422505 3.455475239 GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100041515 100041515 'Gm3383' mRNA 0 3.06 10.8 0 0.09 0.36 0 0.05 0 0.15 0.016666667 0 1.74 0 4.62 0.58 0.111284876 -3.653604142 100041546 100041546 'Ly6c2' mRNA 69.52 50.88 54.8 5.72 4.15 4.71 86.01 76.68 82.3 4.86 81.66333333 1212.03 1047.09 1120.24 58.4 1126.453333 3.21E-174 4.27570284 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 100041574 100041574 '9030025P20Rik' mRNA 445.07 413.2 452.44 14.26 13.2 15.9 11.45 11.38 11.56 14.45333333 11.46333333 401.04 406.05 406.34 436.9033333 404.4766667 0.425801777 -0.124517811 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100041581 100041581 'Zkscan16' mRNA 441 463 437 3.28 3.37 3.45 0.6 0.87 0.67 3.366666667 0.713333333 95 132 100 447 109 1.20E-33 -2.045623558 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100041585 100041585 'Amd2' mRNA 762.84 818.19 793.91 13.03 13.75 14.39 8.2 7.46 7.73 13.72333333 7.796666667 552.57 490.61 504.09 791.6466667 515.7566667 2.79E-09 -0.631424822 00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism GO:0005829///cytosol GO:0004014///adenosylmethionine decarboxylase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0019810///putrescine binding+++GO:0042802///identical protein binding GO:0001701///in utero embryonic development+++GO:0006557///S-adenosylmethioninamine biosynthetic process+++GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0006597///spermine biosynthetic process+++GO:0008295///spermidine biosynthetic process+++GO:0046500///S-adenosylmethionine metabolic process 100041586 100041586 'Gm3417' mRNA 8.2 1.64 7.8 0.71 0.19 0.72 0.56 0 0.1 0.54 0.22 7.37 0 1.29 5.88 2.886666667 0.558025409 -1.048796774 GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0019898///extrinsic component of membrane+++GO:0036126///sperm flagellum GO:0003674///molecular_function GO:0007018///microtubule-based movement+++GO:0008150///biological_process 100041596 100041596 'Gal3st2b' mRNA 7.91 7.09 3.6 0.15 0.14 0.11 0.1 0.04 0 0.133333333 0.046666667 5.69 2.41 0 6.2 2.7 0.413847129 -1.287840593 GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0008150///biological_process+++GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process+++GO:0051923///sulfation 100041621 100041621 'Gm3435' mRNA 259.09 321.88 264.05 8.78 10.6 9.71 5.51 4.63 6.2 9.696666667 5.446666667 193.71 164.9 216.93 281.6733333 191.8466667 0.001622958 -0.569163255 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100041639 100041639 'Gm3448' mRNA 0 1.64 0 0 0.19 0 0 0.43 0 0.063333333 0.143333333 0 5.51 0 0.546666667 1.836666667 0.544601585 2.22977983 GO:0000922///spindle pole+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030286///dynein complex+++GO:0031021///interphase microtubule organizing center+++GO:0036126///sperm flagellum+++GO:0097546///ciliary base GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement+++GO:0008150///biological_process+++GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:1902017///regulation of cilium assembly+++GO:1905799///regulation of intraciliary retrograde transport 100041677 100041677 'Zfp984' mRNA 153.33 129.48 119.36 2.3 1.73 1.79 3.27 2.43 3.42 1.94 3.04 247.77 195.38 245.78 134.0566667 229.6433333 1.08E-04 0.765669666 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100041678 100041678 'Gm3500' mRNA 4.27 8.67 1 0.12 0.28 0.06 0.05 0 0.23 0.153333333 0.093333333 1 0 3.31 4.646666667 1.436666667 0.374771617 -1.68535638 100041708 100041708 'LOC100041708' mRNA 1.02 3.34 0 0.03 0.4 0 0.13 0.23 0.5 0.143333333 0.286666667 5.01 4.56 4.56 1.453333333 4.71 0.339567549 1.713298199 100041722 100041722 '1700049E17Rik2' mRNA 2 2.11 2 0.07 0.07 0.07 0.03 0 0.01 0.07 0.013333333 1 0 0.5 2.036666667 0.5 0.371313523 -2.493392462 100041734 100041734 '4930522L14Rik' mRNA 410.08 465.82 458.25 7.97 9.1 9.53 7.25 5.76 6.15 8.866666667 6.386666667 429.15 330.29 356.12 444.7166667 371.8533333 0.0736431 -0.27297087 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100041735 100041735 'Gm3488' mRNA 35.63 30.15 33.69 0.92 0.77 0.91 0.99 0.63 0.91 0.866666667 0.843333333 44.34 27.73 40.12 33.15666667 37.39666667 0.775494864 0.16348596 100041840 100041840 'Gm10408' mRNA 1.51 1.7 3 0.06 0.06 0.12 0.1 0 0.03 0.08 0.043333333 3.01 0 1 2.07 1.336666667 0.883967497 -0.37619133 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100041874 100041874 'Gm3558' mRNA 9.27 12.38 4.72 0.26 0.34 0.14 0.34 0.09 0.25 0.246666667 0.226666667 14.17 3.52 9.91 8.79 9.2 0.969519197 0.051720599 100041903 100041903 'LOC100041903' mRNA 2.48 4.12 2.07 0.13 0.21 0.11 0.51 0.68 0.61 0.15 0.6 11.24 14.81 13.18 2.89 13.07666667 0.024915707 2.244744654 100041953 100041953 'Sap18b' mRNA 1654.4 1734.56 1638.05 140.64 146.16 147.77 170.19 197.62 188.69 144.8566667 185.5 2291.44 2591.05 2452.84 1675.67 2445.11 1.43E-11 0.534856608 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0061574///ASAP complex GO:0008150///biological_process 100041958 100041958 'Lamtor3-ps' mRNA 1.14 0 0 0.11 0 0 0 0 0 0.036666667 0 0 0 0 0.38 0 0.863090843 -0.97353728 100041979 100041979 'Gm3604' mRNA 82.68 100.82 83.51 0.72 0.99 0.75 0.76 0.54 0.55 0.82 0.616666667 94.89 65.29 64.2 89.00333333 74.79333333 0.442002817 -0.262117856 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100042024 100042024 'Gm3629' mRNA 1.27 0.41 3 0.14 0.05 0.12 0 0 0 0.103333333 0 0 0 0 1.56 0 0.464551436 -2.917308793 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100042055 100042055 'Gm10377' mRNA 0 1 1.53 0 0.08 0.13 0 0 0 0.07 0 0 0 0 0.843333333 0 0.747865658 -1.883366447 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100042074 100042074 'Gm3650' mRNA 74.53 56.22 70.56 3.51 2.61 3.53 2.06 2.62 2.84 3.216666667 2.506666667 50.17 62.35 66.85 67.10333333 59.79 0.66570588 -0.180832832 100042100 100042100 'Gm3667' mRNA 11 11.76 6.7 0.31 0.34 0.2 0.1 0.08 0.11 0.283333333 0.096666667 4.14 3.06 3.99 9.82 3.73 0.173781703 -1.488177209 100042118 100042118 'Gm3678' mRNA 1 0 0 0.21 0 0 0.37 0.19 0.39 0.07 0.316666667 2.01 1 2.02 0.333333333 1.676666667 0.471828131 2.20180938 100042149 100042149 'Gm3696' mRNA 2.15 0 8.35 0.06 0 0.24 0.06 0.19 0.11 0.1 0.12 2.39 7.37 4.01 3.5 4.59 0.863090843 0.330598207 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100042150 100042150 'Nrg2' mRNA 23.84 12.99 22.23 0.22 0.14 0.21 0.13 0.1 0.12 0.19 0.116666667 16.99 7 17 19.68666667 13.66333333 0.495664912 -0.53434166 01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005006///epidermal growth factor-activated receptor activity+++GO:0005102///signaling receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0043125///ErbB-3 class receptor binding GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007399///nervous system development+++GO:0035556///intracellular signal transduction+++GO:0048513///animal organ development+++GO:0051963///regulation of synapse assembly+++GO:0090128///regulation of synapse maturation 100042165 100042165 'Thoc2l' mRNA 980 958 738 5.45 5.24 4.28 2.8 2.42 2.99 4.99 2.736666667 584 495 604 892 561 7.57E-09 -0.676501672 03013///Nucleocytoplasmic transport+++03040///Spliceosome "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus" GO:0003729///mRNA binding GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0048666///neuron development+++GO:0048699///generation of neurons 100042182 100042182 'Gm16434' mRNA 1 0.5 0.5 0.09 0.04 0.05 0 0 0 0.06 0 0 0 0 0.666666667 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100042225 100042225 'Vmn2r130' mRNA 0 2 2 0 0.04 0.05 0 0 0.02 0.03 0.006666667 0 0 1 1.333333333 0.333333333 0.598318529 -1.921052615 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 100042235 100042235 'Gm3739' mRNA 28.71 24.24 31.78 0.53 0.47 0.6 0.37 0.26 0.55 0.533333333 0.393333333 22.79 15.7 28.77 28.24333333 22.42 0.554619773 -0.370726311 100042295 100042295 'Gm3776' mRNA 170.95 155.09 137.88 12.96 11.65 11.1 6.73 5.88 6.55 11.90333333 6.386666667 101.63 86.56 95.51 154.64 94.56666667 0.001512397 -0.7223557 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008150///biological_process 100042304 100042304 'Gm38418' mRNA 0 2 0 0 0.12 0 0.16 0 0.05 0.04 0.07 3 0 1.01 0.666666667 1.336666667 0.789197277 1.00470372 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100042314 100042314 'Gm10639' mRNA 46.19 45.46 51.86 3.5 3.41 4.17 2.3 2.88 2.76 3.693333333 2.646666667 34.77 42.35 40.25 47.83666667 39.12333333 0.503261788 -0.30484384 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005504///fatty acid binding+++GO:0035731///dinitrosyl-iron complex binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process 100042335 100042335 'Rps15a-ps5' mRNA 42.49 65.99 49.37 8.3 12.92 10.24 10.77 13.45 15.06 10.48666667 13.09333333 62.61 75.77 84.09 52.61666667 74.15666667 0.17043443 0.495102662 100042450 100042450 'Smim17' mRNA 7 8 18 0.18 0.2 0.5 0 0.07 0.05 0.293333333 0.04 0 3 2 11 1.666666667 0.024475334 -2.747828818 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100042480 100042480 'Nhsl2' mRNA 1104.81 1134.85 958.41 4.17 5 4.6 2.74 2.81 2.7 4.59 2.75 742.09 629.75 679.39 1066.023333 683.7433333 9.18E-12 -0.650833978 GO:0005575///cellular_component GO:0003674///molecular_function GO:0030154///cell differentiation 100042493 100042493 'Ccl21b' mRNA 40.18 56.27 40.13 1.89 2.69 2.09 0.53 0.41 0.45 2.223333333 0.463333333 12.28 9.46 11.28 45.52666667 11.00666667 2.75E-05 -2.096383954 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001768///establishment of T cell polarity+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002407///dendritic cell chemotaxis+++GO:0002548///monocyte chemotaxis+++GO:0006954///inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031529///ruffle organization+++GO:0031640///killing of cells of other organism+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0034695///response to prostaglandin E+++GO:0035759///mesangial cell-matrix adhesion+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051491///positive regulation of filopodium assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090630///activation of GTPase activity+++GO:1903237///negative regulation of leukocyte tethering or rolling+++GO:2000147///positive regulation of cell motility+++GO:2000529///positive regulation of myeloid dendritic cell chemotaxis+++GO:2000669///negative regulation of dendritic cell apoptotic process 100042503 100042503 'Ndufb4b' mRNA 56.4 39.53 36.83 10.57 7.43 7.33 7.91 9.06 8.24 8.443333333 8.403333333 47.94 53.19 47.97 44.25333333 49.7 0.749855753 0.159157207 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0006979///response to oxidative stress+++GO:0032981///mitochondrial respiratory chain complex I assembly 100042514 100042514 'Sprr2a3' mRNA 0 1 1 0 0.08 0.08 0 0 0.07 0.053333333 0.023333333 0 0 1 0.666666667 0.333333333 0.861384642 -0.920405705 GO:0001533///cornified envelope+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005200///structural constituent of cytoskeleton GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 100042533 100042533 'Gm11578' mRNA 4.95 7.14 3.98 0.19 0.28 0.17 0.38 0.34 0.58 0.213333333 0.433333333 11.04 9.73 16.47 5.356666667 12.41333333 0.157493725 1.360725805 100042555 100042555 'Gm13305' mRNA 112.56 112.98 106.16 3.78 3.71 3.82 4.17 4.53 3.66 3.77 4.12 141.34 151.06 120.54 110.5666667 137.6466667 0.22173864 0.309311062 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage GO:0005575///cellular_component+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0003674///molecular_function+++GO:0004896///cytokine receptor activity+++GO:0004921///interleukin-11 receptor activity+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway 100042591 100042591 'Vmn2r31' mRNA 0 0 1.99 0 0 0.05 0 0.02 0.02 0.016666667 0.013333333 0 0.99 0.94 0.663333333 0.643333333 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 100042625 100042625 'Gstp-ps' mRNA 35.96 46.99 24.25 0.44 0.56 0.31 0.59 0.57 0.49 0.436666667 0.55 56.26 52.72 45.37 35.73333333 51.45 0.214099229 0.540071098 100042698 100042698 'Gm3973' mRNA 47.42 41.37 44.38 1.57 1.04 1.25 0.5 0.84 0.91 1.286666667 0.75 27.07 31.22 35.83 44.39 31.37333333 0.251616638 -0.516621246 100042773 100042773 'Tmed10-ps' mRNA 69.08 88.77 70.74 0.61 0.77 0.67 0.28 0.27 0.22 0.683333333 0.256666667 36.02 34.85 27.37 76.19666667 32.74666667 3.73E-04 -1.236641253 100042784 100042784 'Prdm11' mRNA 214 174 188 1.18 0.89 1.01 0.68 0.4 0.39 1.026666667 0.49 115 83 93 192 97 5.45E-06 -0.999835359 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity "GO:0010468///regulation of gene expression+++GO:0030308///negative regulation of cell growth+++GO:0032259///methylation+++GO:0043408///regulation of MAPK cascade+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:2000271///positive regulation of fibroblast apoptotic process" 100042807 100042807 'Eif3j2' mRNA 464.22 440.29 236.21 10.72 10.01 5.79 5.95 8.8 9.32 8.84 8.023333333 296.26 427.98 449.2 380.24 391.1466667 0.869078234 0.045034171 GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex GO:0003743///translation initiation factor activity+++GO:0042802///identical protein binding GO:0001732///formation of cytoplasmic translation initiation complex 100042849 100042849 'Gm4064' mRNA 0 0 0.11 0 0 0 0.02 0 0 0 0.006666667 0.67 0 0 0.036666667 0.223333333 GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100042856 100042856 'Gvin2' mRNA 115.92 186.52 61.36 0.69 1.1 0.39 4.62 4.31 4.79 0.726666667 4.573333333 897.94 811.48 888.45 121.2666667 865.9566667 5.94E-12 2.849736951 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0005525///GTP binding GO:0008150///biological_process 100042874 100042874 'Gm10256' mRNA 0 0 0.11 0 0 0 0.02 0 0.01 0 0.01 0.67 0 0.29 0.036666667 0.32 GO:0005575///cellular_component+++GO:0005681///spliceosomal complex GO:0003674///molecular_function+++GO:0003723///RNA binding "GO:0008150///biological_process+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100042881 100042881 'Gm10352' mRNA 0 0 0.11 0 0 0 0.02 0 0.01 0 0.01 0.67 0 0.29 0.036666667 0.32 GO:0005575///cellular_component+++GO:0005681///spliceosomal complex GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0008150///biological_process+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100042891 100042891 'Vmn2r47' mRNA 0.36 0 0 0.01 0 0 0 0 0 0.003333333 0 0.17 0 0 0.12 0.056666667 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 100042894 100042894 'Vmn2r46' mRNA 12.99 5.15 4.53 0.3 0.12 0.11 0.07 0.03 0.05 0.176666667 0.05 3.52 1.22 2.58 7.556666667 2.44 0.182930001 -1.814176854 100042945 100042945 'Gm4120' mRNA 14.84 11.4 15.62 0.68 0.52 0.76 0.42 0.55 0.38 0.653333333 0.45 10.6 13.46 9.15 13.95333333 11.07 0.720293678 -0.336983313 100042960 100042960 'Gm4131' mRNA 462 452 489 11.9 11.46 13.36 0.83 0.64 1.16 12.24 0.876666667 37 28 50 467.6666667 38.33333333 6.98E-68 -3.623701249 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100043002 100043002 'Llph-ps2' mRNA 105.78 114.01 122.13 10.23 10.94 12.53 24.42 23.94 32.38 11.23333333 26.91333333 288.77 275.5 369.48 113.9733333 311.25 8.16E-14 1.436937032 100043034 100043034 'Rex2' mRNA 4.44 2.9 2.98 0.06 0.04 0.04 0 0.06 0.1 0.046666667 0.053333333 0 5.49 8.47 3.44 4.653333333 0.713003394 0.705917522 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 100043059 100043059 'Gm4199' mRNA 17.91 19.82 10.69 0.79 0.86 0.5 0.24 0.27 0.42 0.716666667 0.31 6.21 6.91 10.6 16.14 7.906666667 0.198025538 -1.063892415 100043108 100043108 'Cyp2c69' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 100043123 100043123 'Cd300ld4' mRNA 3.16 2 2.68 0.09 0.1 0.11 0.82 0.55 1.7 0.1 1.023333333 26.64 20.23 40.01 2.613333333 28.96 1.11E-05 3.608539515 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004888///transmembrane signaling receptor activity GO:0008150///biological_process 100043133 100043133 '9130023H24Rik' mRNA 272.77 309.73 371.99 4.14 4.62 5.98 3.84 3.73 3.22 4.913333333 3.596666667 291.38 276.39 236.84 318.1633333 268.2033333 0.180585619 -0.264267533 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100043231 100043231 'Gm4303' mRNA 0 0 0.67 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.223333333 0 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006406///mRNA export from nucleus 100043235 100043235 'Gm4305' mRNA 0 0 0.67 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.223333333 0 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003723///RNA binding GO:0008150///biological_process 100043239 100043239 'Gm4307' mRNA 0 0 0.67 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.223333333 0 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006406///mRNA export from nucleus+++GO:0008150///biological_process 100043257 100043257 'Rbm3-ps' mRNA 21.09 3.37 12.7 1.14 0.18 0.73 0.77 0.65 0.88 0.683333333 0.766666667 16.33 13.34 17.97 12.38666667 15.88 0.740213982 0.335935661 100043272 100043272 'Inafm2' mRNA 592 569 676 10.64 10.06 12.89 10.98 10.28 11.58 11.19666667 10.94666667 703 643 718 612.3333333 688 0.28301579 0.151447434 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005246///calcium channel regulator activity 100043300 100043300 'Esp16' mRNA 0 0 1 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005615///extracellular space GO:0005186///pheromone activity GO:0008150///biological_process 100043314 100043314 'Tigit' mRNA 2 11 6 0.1 0.58 0.38 0.7 0.58 0.93 0.353333333 0.736666667 12 11 16 6.333333333 13 0.281732195 1.030499999 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0032695///negative regulation of interleukin-12 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0050868///negative regulation of T cell activation 100043324 100043324 'Bnip3l-ps' mRNA 3.41 5.85 1.95 0.17 0.29 0.1 0.39 0 0 0.186666667 0.13 8.98 0 0 3.736666667 2.993333333 0.936866118 -0.185702619 100043332 100043332 'Ankrd66' mRNA 51 57 43 2.33 2.52 1.98 0.53 0.33 0.95 2.276666667 0.603333333 14 8 23 50.33333333 15 2.94E-04 -1.754919045 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100043381 100043381 'Gm14308' mRNA 141.42 170.85 144.78 0.9 1.12 0.97 0.58 0.36 0.21 0.996666667 0.383333333 112.87 73.61 35.24 152.35 73.90666667 0.001185647 -1.064424548 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 100043387 100043387 'Gm14305' mRNA 106.74 131.17 123.31 3.85 4.66 4.72 4.63 4.17 3.6 4.41 4.133333333 147.58 129.86 111.16 120.4066667 129.5333333 0.774315128 0.090397201 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 100043403 100043403 'Gm14410' mRNA 248.33 252.37 230.78 3.26 3.26 3.22 2.48 2.52 2.49 3.246666667 2.496666667 217.31 215.49 211.58 243.8266667 214.7933333 0.301178961 -0.193689469 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 100043456 100043456 'Gm10681' mRNA 146.57 170.61 165.15 5.11 5.87 6.17 0.78 0.19 0.29 5.716666667 0.42 25.43 6.09 9.45 160.7766667 13.65666667 1.56E-22 -3.607876032 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0000253///3-keto sterol reductase activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0035634///response to stilbenoid+++GO:0042448///progesterone metabolic process+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051412///response to corticosterone 100043461 100043461 'Gm4450' mRNA 260.89 197.09 232.96 8.91 7.29 8.72 0.62 0.61 0.26 8.306666667 0.496666667 16.57 20.91 6.09 230.3133333 14.52333333 7.72E-36 -4.049790498 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006694///steroid biosynthetic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0051412///response to corticosterone 100043468 100043468 'Zfp955b' mRNA 480.28 522.8 508.91 7.4 7.8 8.29 5.22 5.16 4.98 7.83 5.12 407.15 380.48 362.82 503.9966667 383.4833333 0.001567477 -0.407265064 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100043474 100043474 'Olfr1564' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007268///chemical synaptic transmission+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 100043497 100043497 'Nat8f7' mRNA 4.7 1.39 3.79 0.22 0.07 0.18 0.39 0.25 0.32 0.156666667 0.32 9.98 6.28 7.99 3.293333333 8.083333333 0.258413973 1.438613086 00480///Glutathione metabolism GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004402///histone acetyltransferase activity+++GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0003401///axis elongation+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0016573///histone acetylation+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0050435///amyloid-beta metabolic process 100043508 100043508 'Ptges3-ps' mRNA 171.23 138.39 112.27 6.4 5.1 4.45 4.55 4.02 4.59 5.316666667 4.386666667 139.7 120.5 136.6 140.63 132.2666667 0.747865658 -0.099508632 100043597 100043597 'Srcap' mRNA 4071 3926 3039 19.51 18.49 15.45 12.75 11.67 13.58 17.81666667 12.66666667 3064 2741 3162 3678.666667 2989 4.15E-04 -0.306334409 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042393///histone binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0016458///gene silencing+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043486///histone exchange 100043684 100043684 'Amy2a4' mRNA 0 2.31 2.58 0 0.03 0.04 0.01 0.01 0.02 0.023333333 0.013333333 0.67 0.68 1.68 1.63 1.01 0.598318529 -1.921052615 00500///Starch and sucrose metabolism+++04970///Salivary secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption GO:0005615///extracellular space GO:0004556///alpha-amylase activity+++GO:0005509///calcium ion binding+++GO:0016160///amylase activity+++GO:0031404///chloride ion binding+++GO:0103025///alpha-amylase activity (releasing maltohexaose) GO:0008150///biological_process+++GO:0016052///carbohydrate catabolic process 100043686 100043686 'Amy2a3' mRNA 10 2.31 1.85 0.15 0.03 0.03 0.01 0.01 0.02 0.07 0.013333333 0.67 0.68 1.68 4.72 1.01 0.102131701 -3.587271315 00500///Starch and sucrose metabolism+++04970///Salivary secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption GO:0005615///extracellular space GO:0004556///alpha-amylase activity+++GO:0005509///calcium ion binding+++GO:0016160///amylase activity+++GO:0031404///chloride ion binding+++GO:0103025///alpha-amylase activity (releasing maltohexaose) GO:0008150///biological_process+++GO:0016052///carbohydrate catabolic process 100043688 100043688 'Amy2a2' mRNA 0 2.31 2.58 0 0.03 0.04 0.01 0.01 0.02 0.023333333 0.013333333 0.67 0.68 1.68 1.63 1.01 0.598318529 -1.921052615 00500///Starch and sucrose metabolism+++04970///Salivary secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space "GO:0003824///catalytic activity+++GO:0004556///alpha-amylase activity+++GO:0005509///calcium ion binding+++GO:0016160///amylase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0031404///chloride ion binding+++GO:0043169///cation binding+++GO:0046872///metal ion binding+++GO:0103025///alpha-amylase activity (releasing maltohexaose)" GO:0005975///carbohydrate metabolic process+++GO:0008150///biological_process+++GO:0008152///metabolic process+++GO:0016052///carbohydrate catabolic process 100043695 100043695 'Gm15483' mRNA 22.96 18.31 29.72 0.75 0.59 1.03 0.16 0.18 0.36 0.79 0.233333333 5.65 6.17 12.19 23.66333333 8.003333333 0.022679834 -1.604566993 100043757 100043757 'Zfp831' mRNA 0 0 1 0 0 0.01 0.01 0.03 0.01 0.003333333 0.016666667 3 6 2 0.333333333 3.666666667 0.130239513 3.349391185 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100043772 100043772 'Zfp850' mRNA 57 72 68 0.73 0.9 0.92 0.51 0.44 0.36 0.85 0.436666667 52 44 31 65.66666667 42.33333333 0.084812962 -0.648315074 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100043805 100043805 'Gm10224' mRNA 33.04 50.05 43.85 3.21 4.83 4.53 5.45 4.5 5.3 4.19 5.083333333 64.03 51.53 60.13 42.31333333 58.56333333 0.25014886 0.46047832 100043813 100043813 'Rps27rt' mRNA 111.22 95.44 229.91 32.07 27.84 70.52 33.22 41.2 28.05 43.47666667 34.15666667 129.76 155.55 105.03 145.5233333 130.1133333 0.641550165 -0.194043957 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0000028///ribosomal small subunit assembly+++GO:0006364///rRNA processing+++GO:0006412///translation 100043899 100043899 'R3hdml' mRNA 5 0 0 0.29 0 0 0.1 0.19 0.08 0.096666667 0.123333333 2 2 2 1.666666667 2 0.916235181 0.273758542 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0030414///peptidase inhibitor activity GO:0008150///biological_process+++GO:0010466///negative regulation of peptidase activity 100043914 100043914 'Zfp968' mRNA 2.3 0 2.16 0.07 0 0.07 0 0 0.01 0.046666667 0.003333333 0 0 0.43 1.486666667 0.143333333 0.468848267 -2.893033412 GO:0005575///cellular_component "GO:0006355///regulation of transcription, DNA-templated" 100043915 100043915 'Gm4724' mRNA 804.32 751.22 703.64 6.49 5.93 6.32 4.75 5.29 5.51 6.246666667 5.183333333 647.02 733.24 738.1 753.06 706.12 0.436711449 -0.101527541 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 100043920 100043920 'Fam205a4' mRNA 48.15 20.94 74.31 0.46 0.19 0.7 0.22 0.43 0.55 0.45 0.4 25.95 57.68 70.4 47.8 51.34333333 0.91397597 0.070912002 GO:0016020///membrane+++GO:0016021///integral component of membrane 100044193 100044193 'Gm20939' mRNA 562.2 540.33 521.68 6.41 6.06 6.31 2.67 2.39 2.05 6.26 2.37 270.19 236.09 200.85 541.4033333 235.71 2.25E-18 -1.213675687 GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated" 100044509 100044509 'Tgfbr3l' mRNA 167 171 136 8.87 9.11 7.77 3.52 2.88 2.89 8.583333333 3.096666667 73 59 61 158 64.33333333 4.59E-08 -1.305546834 GO:0005615///extracellular space+++GO:0009986///cell surface GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005539///glycosaminoglycan binding+++GO:0050431///transforming growth factor beta binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016477///cell migration+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway 100045125 100045125 'Gm17768' mRNA 2888.59 2660.37 2321.03 27.17 24.6 23.16 13.85 11.15 12.45 24.97666667 12.48333333 1695.43 1333.26 1475.83 2623.33 1501.506667 4.79E-21 -0.816001709 100045778 100045778 'Rnf223' mRNA 10 10 12 0.38 0.38 0.49 0.17 0.07 0.14 0.416666667 0.126666667 5 2 4 10.66666667 3.666666667 0.126040545 -1.561754382 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 100045792 100045792 'Ect2l' mRNA 17.06 18.25 21 0.27 0.28 0.35 0.18 0.19 0.17 0.3 0.18 13 13.56 12.01 18.77 12.85666667 0.425428642 -0.575560353 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 100048534 100048534 'Cfap43' mRNA 3016 3010 2963 33.04 32.67 34.86 2.55 2.31 2.81 33.52333333 2.556666667 274 241 288 2996.333333 267.6666667 0 -3.497478942 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0007420///brain development+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:0090660///cerebrospinal fluid circulation 100048644 100048644 'Pet117' mRNA 0 1.23 0 0 0.5 0 0 0 0 0.166666667 0 0 0 0 0.41 0 0.863090843 -0.97353728 GO:0005739///mitochondrion GO:0033617///mitochondrial respiratory chain complex IV assembly 100048658 100048658 'Ddx43' mRNA 3 3 1 0.13 0.08 0.05 0.06 0.12 0.12 0.086666667 0.1 2 3 3 2.333333333 2.666666667 0.918949756 0.200074997 GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 100061 100061 'Lrrc19' mRNA 19 35 48 0.28 0.5 0.78 0.37 0.27 0.25 0.52 0.296666667 29 19 19 34 22.33333333 0.277645791 -0.634898514 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0001817///regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0032637///interleukin-8 production+++GO:0038008///TRAF-mediated signal transduction+++GO:0048874///host-mediated regulation of intestinal microbiota composition+++GO:0050727///regulation of inflammatory response+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 100066 100066 'Cyp2j11' mRNA 20 19 13 0.62 0.8 0.59 0.25 0 0.05 0.67 0.1 8 0 2 17.33333333 3.333333333 0.013259787 -2.396982626 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 100072 100072 'Camta1' mRNA 509 573 322 7.39 7.77 4.99 4.1 4.06 3.99 6.716666667 4.05 242 240 234 468 238.6666667 3.04E-08 -0.972317124 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0043565///sequence-specific DNA binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050885///neuromuscular process controlling balance+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 100073351 100073351 'Yy2' mRNA 69 66 52 1.33 1.25 1.06 1.34 1.23 1.62 1.213333333 1.396666667 80 72 94 62.33333333 82 0.242677518 0.38789509 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0031519///PcG protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 100087 100087 'Kti12' mRNA 372 319 273 14.05 11.88 10.94 20.78 20.89 19.17 12.29 20.28 632 620 564 321.3333333 605.3333333 3.89E-12 0.905244039 GO:0033588///Elongator holoenzyme complex GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0002098///tRNA wobble uridine modification+++GO:0006357///regulation of transcription by RNA polymerase II 100088 100088 'Rcc1' mRNA 220 192 179 5.39 4.62 4.64 13.79 12.7 12.99 4.883333333 13.16 648 582 590 197 606.6666667 2.22E-34 1.611813861 GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding+++GO:0031491///nucleosome binding+++GO:0031492///nucleosomal DNA binding+++GO:0042393///histone binding+++GO:0043199///sulfate binding+++GO:0046982///protein heterodimerization activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007059///chromosome segregation+++GO:0007088///regulation of mitotic nuclear division+++GO:0031291///Ran protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:1901673///regulation of mitotic spindle assembly 100090 100090 'Zbtb48' mRNA 275 283 263 6.59 6.84 6.78 4.78 4.34 4.57 6.736666667 4.563333333 226 202 208 273.6666667 212 0.022854995 -0.380209395 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0045893///positive regulation of transcription, DNA-templated" 100101806 100101806 'Srp54c' mRNA 1048.51 1102.68 1112.9 21.89 22.4 24.4 24.22 25.47 21.37 22.89666667 23.68666667 1386.96 1447.65 1203.98 1088.03 1346.196667 0.003804035 0.294179216 03060///Protein export "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0048500///signal recognition particle" GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008312///7S RNA binding+++GO:0019003///GDP binding+++GO:0030942///endoplasmic reticulum signal peptide binding "GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0030851///granulocyte differentiation+++GO:0045047///protein targeting to ER" 100101807 100101807 'Fam177a2' mRNA 757.94 141.17 752.8 10.61 1.94 11.18 10.72 20.6 10.81 7.91 14.04333333 881.73 1654.6 860.77 550.6366667 1132.366667 0.26869974 1.015458982 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100101919 100101919 'Dnah7c' mRNA 84.76 57.08 77.3 0.36 0.24 0.35 0.02 0.01 0.02 0.316666667 0.016666667 4.37 3.39 4 73.04666667 3.92 8.68E-14 -4.32529758 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0036159///inner dynein arm assembly 100102 100102 'Pcsk9' mRNA 437 457 468 6.77 6.96 7.69 0.59 0.94 0.83 7.14 0.786666667 44 68 60 454 57.33333333 1.76E-55 -2.996722564 04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:1990666///PCSK9-LDLR complex+++GO:1990667///PCSK9-AnxA2 complex GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019871///sodium channel inhibitor activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0030547///receptor inhibitor activity+++GO:0034185///apolipoprotein binding+++GO:0034189///very-low-density lipoprotein particle binding+++GO:0034190///apolipoprotein receptor binding+++GO:0043621///protein self-association+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0070326///very-low-density lipoprotein particle receptor binding GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001920///negative regulation of receptor recycling+++GO:0002092///positive regulation of receptor internalization+++GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006915///apoptotic process+++GO:0007041///lysosomal transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009267///cellular response to starvation+++GO:0010469///regulation of signaling receptor activity+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016485///protein processing+++GO:0016540///protein autoprocessing+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation+++GO:0032799///low-density lipoprotein receptor particle metabolic process+++GO:0032802///low-density lipoprotein particle receptor catabolic process+++GO:0032803///regulation of low-density lipoprotein particle receptor catabolic process+++GO:0032805///positive regulation of low-density lipoprotein particle receptor catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0042157///lipoprotein metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043523///regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:1905596///negative regulation of low-density lipoprotein particle receptor binding+++GO:1905598///negative regulation of low-density lipoprotein receptor activity+++GO:1905601///negative regulation of receptor-mediated endocytosis involved in cholesterol transport+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 100113365 100113365 'Nlgn4l' mRNA 36 21 7 0.39 0.22 0.08 0.01 0.12 0.05 0.23 0.06 1 10 5 21.33333333 5.333333333 0.027191821 -1.97926867 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098690///glycinergic synapse+++GO:0098793///presynapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0031404///chloride ion binding+++GO:0038023///signaling receptor activity+++GO:0042043///neurexin family protein binding+++GO:0042803///protein homodimerization activity+++GO:0097110///scaffold protein binding GO:0002124///territorial aggressive behavior+++GO:0003360///brainstem development+++GO:0007158///neuron cell-cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0008049///male courtship behavior+++GO:0021549///cerebellum development+++GO:0035176///social behavior+++GO:0035265///organ growth+++GO:0048488///synaptic vesicle endocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0071625///vocalization behavior+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly 100113398 100113398 'Adat3' mRNA 102 140 123 4.31 5.84 5.52 4.01 4.45 3.65 5.223333333 4.036666667 109 118 96 121.6666667 107.6666667 0.530614183 -0.187772504 GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0052717///tRNA-specific adenosine-34 deaminase activity GO:0008033///tRNA processing 100121 100121 'Tdrd7' mRNA 1451.72 1640 1147.77 20.14 22.51 16.56 10.81 12.05 11.46 19.73666667 11.44 919.29 980.01 933.74 1413.163333 944.3466667 2.17E-08 -0.586170168 GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0033391///chromatoid body+++GO:0035770///ribonucleoprotein granule+++GO:0043186///P granule+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding GO:0002089///lens morphogenesis in camera-type eye+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0034587///piRNA metabolic process+++GO:0070306///lens fiber cell differentiation 100125586 100125586 'Vmn2r2' mRNA 11 13.8 7.32 0.19 0.23 0.14 0.05 0.02 0.04 0.186666667 0.036666667 3 1.14 2.29 10.70666667 2.143333333 0.037938664 -2.375159065 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 100126226 100126226 'Krt83' mRNA 6 18 13 0.2 0.58 0.45 0.14 0.12 0.15 0.41 0.136666667 5 4 5 12.33333333 4.666666667 0.141800955 -1.414646122 GO:0045095///keratin filament GO:0003674///molecular_function GO:0007568///aging+++GO:0042633///hair cycle 100126774 100126774 'Esp18' mRNA 1 3 2 0.05 0.14 0.1 0.04 0 0.09 0.096666667 0.043333333 1 0 2 2 1 0.705140992 -1.013641661 GO:0005615///extracellular space GO:0005186///pheromone activity GO:0008150///biological_process 100126778 100126778 'Esp8' mRNA 2 1 0 0.15 0.07 0 0.25 0.65 0.26 0.073333333 0.386666667 4 10 4 1 6 0.112118022 2.598123416 GO:0005615///extracellular space GO:0005186///pheromone activity GO:0008150///biological_process 100126824 100126824 'Sco2' mRNA 165.43 156.96 158.54 8.26 7.74 8.4 8.7 7.23 9.66 8.133333333 8.53 200.08 161.99 214.77 160.31 192.28 0.261583403 0.250212809 05230///Central carbon metabolism in cancer GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030016///myofibril+++GO:0031305///integral component of mitochondrial inner membrane GO:0005507///copper ion binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding GO:0001654///eye development+++GO:0001701///in utero embryonic development+++GO:0003012///muscle system process+++GO:0006878///cellular copper ion homeostasis+++GO:0008535///respiratory chain complex IV assembly+++GO:0014823///response to activity+++GO:0022904///respiratory electron transport chain+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0055070///copper ion homeostasis 100129 100129 'Gpr153' mRNA 229 234 240 3.25 3.28 3.63 2.67 2.69 2.44 3.386666667 2.6 216 214 192 234.3333333 207.3333333 0.338633465 -0.189853708 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 100141474 100141474 '4933428G20Rik' mRNA 89.1 72.39 74.6 1.08 0.73 0.98 0.85 0.86 1.04 0.93 0.916666667 104.5 70.26 97.65 78.69666667 90.80333333 0.589519909 0.191754272 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100151772 100151772 'Srsx' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100155 100155 'Shoc1' mRNA 57 66 68 0.47 0.53 0.59 0.06 0.04 0.11 0.53 0.07 9 6 15 63.66666667 10 1.01E-08 -2.685581697 GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0007131///reciprocal meiotic recombination+++GO:0051321///meiotic cell cycle 100163 100163 'Pafah2' mRNA 887 895 803 15.37 15.29 15.08 19.04 17.78 20.28 15.24666667 19.03333333 1260 1155 1299 861.6666667 1238 4.93E-09 0.512192013 00565///Ether lipid metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0047179///platelet-activating factor acetyltransferase activity GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0043066///negative regulation of apoptotic process 100169 100169 'Phactr4' mRNA 1041.79 1099.65 861.07 12.35 12.79 10.79 7.48 6.7 7.7 11.97666667 7.293333333 741.96 655.55 742.9 1000.836667 713.47 1.10E-06 -0.497447844 GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019888///protein phosphatase regulator activity+++GO:0072542///protein phosphatase activator activity GO:0001755///neural crest cell migration+++GO:0001843///neural tube closure+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030036///actin cytoskeleton organization+++GO:0043085///positive regulation of catalytic activity+++GO:0043086///negative regulation of catalytic activity+++GO:0048484///enteric nervous system development+++GO:0051726///regulation of cell cycle+++GO:0061386///closure of optic fissure+++GO:2001045///negative regulation of integrin-mediated signaling pathway 100169864 100169864 'Gm44504' mRNA 10.58 14.81 8.52 0.57 0.79 0.49 0 1.1 1.62 0.616666667 0.906666667 0 22.79 33.4 11.30333333 18.73 0.471828131 0.792268149 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0071818///BAT3 complex GO:0051087///chaperone binding GO:0071816///tail-anchored membrane protein insertion into ER membrane 100169868 100169868 'Gm3173' mRNA 16.04 14.39 10.76 0.47 0.41 0.35 0.24 0.39 0.54 0.41 0.39 10.03 15.66 21.32 13.73 15.67 0.831214691 0.200147364 100170401 100170401 'EU599041' mRNA 2 1.01 0 0.08 0.03 0 0 0 0 0.036666667 0 0 0 0 1.003333333 0 0.614783931 -2.421998967 GO:0005575///cellular_component GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0010033///response to organic substance+++GO:0032526///response to retinoic acid" 100177 100177 'Zmym6' mRNA 981 945 997 10.5 10 11.38 5.08 4.64 4.6 10.62666667 4.773333333 533 481 467 974.3333333 493.6666667 1.29E-21 -0.995219934 GO:0008270///zinc ion binding GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis 100182 100182 'Akna' mRNA 669 605 517 8.6 7.7 7.08 12.02 14.47 12.4 7.793333333 12.96333333 1167 1264 1104 597 1178.333333 9.41E-21 0.973242896 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0005515///protein binding GO:0001837///epithelial to mesenchymal transition+++GO:0007399///nervous system development+++GO:0021849///neuroblast division in subventricular zone+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0060232///delamination+++GO:0060234///neuroblast delamination 100188919 100188919 'Gm45915' mRNA 69 55 61 1.84 1.44 1.72 1.55 1.64 1.72 1.666666667 1.636666667 67 69 72 61.66666667 69.33333333 0.697221503 0.156949649 GO:1990782///protein tyrosine kinase binding GO:0042110///T cell activation+++GO:0061099///negative regulation of protein tyrosine kinase activity 100189605 100189605 'Mup19' mRNA 0 2 0 0 0.15 0 0 0 0 0.05 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0005009///insulin-activated receptor activity+++GO:0005549///odorant binding+++GO:0005550///pheromone binding+++GO:0036094///small molecule binding "GO:0006112///energy reserve metabolic process+++GO:0007610///behavior+++GO:0008150///biological_process+++GO:0008286///insulin receptor signaling pathway+++GO:0009060///aerobic respiration+++GO:0010628///positive regulation of gene expression+++GO:0010888///negative regulation of lipid storage+++GO:0010907///positive regulation of glucose metabolic process+++GO:0031649///heat generation+++GO:0042593///glucose homeostasis+++GO:0045475///locomotor rhythm+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045834///positive regulation of lipid metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070584///mitochondrion morphogenesis+++GO:0071394///cellular response to testosterone stimulus+++GO:0071396///cellular response to lipid" 100198 100198 'H6pd' mRNA 455 447 187 4.97 4.81 2.15 7.37 7.23 6.88 3.976666667 7.16 777 732 697 363 735.3333333 0.008447766 1.024325498 00030///Pentose phosphate pathway+++01200///Carbon metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005829///cytosol+++GO:0009331///glycerol-3-phosphate dehydrogenase complex+++GO:0016529///sarcoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004345///glucose-6-phosphate dehydrogenase activity+++GO:0004367///glycerol-3-phosphate dehydrogenase [NAD+] activity+++GO:0004368///glycerol-3-phosphate dehydrogenase (quinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016614///oxidoreductase activity, acting on CH-OH group of donors+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016787///hydrolase activity+++GO:0017057///6-phosphogluconolactonase activity+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0047934///glucose 1-dehydrogenase (NAD+) activity+++GO:0047935///glucose 1-dehydrogenase (NADP+) activity+++GO:0047936///glucose 1-dehydrogenase [NAD(P)] activity+++GO:0050661///NADP binding+++GO:0051287///NAD binding" "GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006098///pentose-phosphate shunt+++GO:0006116///NADH oxidation+++GO:0006127///glycerophosphate shuttle+++GO:0006734///NADH metabolic process+++GO:0006739///NADP metabolic process+++GO:0008152///metabolic process+++GO:0009051///pentose-phosphate shunt, oxidative branch+++GO:0045821///positive regulation of glycolytic process+++GO:0046168///glycerol-3-phosphate catabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0071320///cellular response to cAMP+++GO:0071356///cellular response to tumor necrosis factor+++GO:0097305///response to alcohol+++GO:2000064///regulation of cortisol biosynthetic process" 100201 100201 'Tmem64' mRNA 716 851 587 8.19 9.58 7.13 7.24 7.06 8.21 8.3 7.503333333 728 694 800 718 740.6666667 0.820936375 0.039262656 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0043462///regulation of ATPase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0090090///negative regulation of canonical Wnt signaling pathway 100206 100206 'Adprhl2' mRNA 1256 1264 1248 55.06 54.68 58.04 41.04 37.88 41.2 55.92666667 40.04 1075 968 1044 1256 1029 6.09E-04 -0.300549793 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016604///nuclear body+++GO:0090734///site of DNA damage "GO:0000287///magnesium ion binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004649///poly(ADP-ribose) glycohydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0061463///O-acetyl-ADP-ribose deacetylase activity" GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0071451///cellular response to superoxide 100210 100210 'Gpn2' mRNA 221 224 243 9.9 9.9 11.46 13.39 12 13.61 10.42 13 346 301 339 229.3333333 328.6666667 0.001706318 0.504226743 GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity 100213 100213 'Rusc2' mRNA 1845 1812 1416 17.7 16.84 14.5 10.07 9.16 9.72 16.34666667 9.65 1210 1075.97 1124 1691 1136.656667 1.32E-10 -0.58118163 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle GO:0031267///small GTPase binding GO:0008150///biological_process 100216455 100216455 'Gm14124' mRNA 4 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 1.333333333 0 0.535994789 -2.842745962 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 100216474 100216474 'Ttll2' mRNA 9 7 9 0.25 0.25 0.3 0.06 0 0.06 0.266666667 0.04 2 0 2 8.333333333 1.333333333 0.048180103 -2.665874368 GO:0005929///cilium GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation 100226 100226 'Stx12' mRNA 1726 1841 1721 41.73 43.83 44.14 49.8 43.66 45.95 43.23333333 46.47 2369 2028 2116 1762.666667 2171 1.99E-04 0.287734153 04145///Phagosome GO:0000139///Golgi membrane+++GO:0000407///phagophore assembly site+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031083///BLOC-1 complex+++GO:0031201///SNARE complex+++GO:0031901///early endosome membrane+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045335///phagocytic vesicle+++GO:0055038///recycling endosome membrane+++GO:0098837///postsynaptic recycling endosome GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding GO:0000045///autophagosome assembly+++GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016189///synaptic vesicle to endosome fusion+++GO:0016192///vesicle-mediated transport+++GO:0033344///cholesterol efflux+++GO:0048278///vesicle docking+++GO:0050821///protein stabilization+++GO:0061025///membrane fusion 100233175 100233175 'Gon7' mRNA 328.15 292.3 312.86 17.46 15.36 17.66 15.85 17.53 15.75 16.82666667 16.37666667 341.88 368.78 328.47 311.1033333 346.3766667 0.416704324 0.141789653 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol 100233207 100233207 'Gm17359' mRNA 3 4 3 0.09 0.12 0.12 0.59 0.73 0.42 0.11 0.58 13 16 12 3.333333333 13.66666667 0.029128132 2.028095781 100233208 100233208 'Gm10778' mRNA 216.03 153.2 173.56 2.45 1.71 2.09 1.48 1.1 1.19 2.083333333 1.256666667 150.76 109.56 117.5 180.93 125.94 0.020564904 -0.542292792 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 100270744 100270744 'Btbd18' mRNA 8 19 13 0.13 0.29 0.22 0.25 0.17 0.22 0.213333333 0.213333333 18 12 15 13.33333333 15 0.863090843 0.15759541 GO:0005634///nucleus GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:1990511///piRNA biosynthetic process 100271704 100271704 'Gm17660' mRNA 10 12 5 1.57 1.88 0.83 1.1 3.13 2.58 1.426666667 2.27 8 22 18 9 16 0.324978233 0.838925953 100271882 100271882 'Gm14139' mRNA 0 0 3 0 0 0.11 0.06 0 0 0.036666667 0.02 2 0 0 1 0.666666667 0.863090843 -0.691052305 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100273 100273 'Osbpl9' mRNA 2306.22 2378.76 2281.96 45.17 45.44 46.84 55.82 56.55 60.62 45.81666667 57.66333333 3327.86 3315.1 3461.96 2322.313333 3368.306667 4.14E-16 0.524966739 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0015918///sterol transport 100294583 100294583 'Alkal2' mRNA 0 0 4.01 0 0 0.17 0.04 0.04 0 0.056666667 0.026666667 1.01 1 0 1.336666667 0.67 0.768105727 -1.081737999 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0030298///receptor signaling protein tyrosine kinase activator activity+++GO:0030971///receptor tyrosine kinase binding GO:0010976///positive regulation of neuron projection development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070378///positive regulation of ERK5 cascade 100302688 100302688 'Gm17455' mRNA 65 42 46 5.71 3.48 4.19 6.71 7.66 7.55 4.46 7.306666667 80 99 91 51 90 0.011844849 0.810790402 GO:0016020///membrane+++GO:0016021///integral component of membrane 100303732 100303732 'Zfp967' mRNA 1.21 1.43 2.03 0.04 0.04 0.07 0.06 0 0 0.05 0.02 3.2 0 0 1.556666667 1.066666667 0.876979773 -0.468543913 GO:0005575///cellular_component GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100303744 100303744 'Sprr2a2' mRNA 0.5 0 4.5 0.01 0 0.07 0.06 0.09 0.08 0.026666667 0.076666667 4.5 6.5 6 1.666666667 5.666666667 0.268697535 1.944043279 GO:0001533///cornified envelope+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005200///structural constituent of cytoskeleton GO:0007010///cytoskeleton organization+++GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 100310809 100310809 'Gm10509' mRNA 214.7 273.97 233.71 4 5.02 4.62 3.69 3.51 2.96 4.546666667 3.386666667 228.01 212.01 177.38 240.7933333 205.8 0.254498118 -0.234408453 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 100310872 100310872 'Dynlt1a' mRNA 565.2 533.31 543.94 6.11 5.67 6.24 3.73 3.79 4.24 6.006666667 3.92 396.88 394.43 437.32 547.4833333 409.5433333 5.60E-04 -0.431554977 05132///Salmonella infection GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0030027///lamellipodium+++GO:0030286///dynein complex+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0043657///host cell+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0099503///secretory vesicle GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030742///GTP-dependent protein binding+++GO:0031681///G-protein beta-subunit binding+++GO:0042802///identical protein binding+++GO:0045505///dynein intermediate chain binding GO:0000132///establishment of mitotic spindle orientation+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0008150///biological_process+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0016358///dendrite development+++GO:0019060///intracellular transport of viral protein in host cell+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0043087///regulation of GTPase activity+++GO:0048812///neuron projection morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0051301///cell division+++GO:0051493///regulation of cytoskeleton organization+++GO:0060548///negative regulation of cell death+++GO:0061564///axon development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 100312485 100312485 'Vmn1r221' mRNA 0 2 0 0 0.14 0 0 0 0 0.046666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 100312956 100312956 'Pate3' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region 100317 100317 'AU040320' mRNA 1417.96 1569.11 1356 17.38 18.99 17.63 12.58 12.33 12.07 18 12.32666667 1178.29 1125 1086.84 1447.69 1130.043333 8.37E-06 -0.367917161 GO:0000139///Golgi membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0001675///acrosome assembly+++GO:0001764///neuron migration+++GO:0007283///spermatogenesis+++GO:0010996///response to auditory stimulus+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0030317///flagellated sperm motility 100328588 100328588 'Il4i1b' mRNA 7.75 0 0 0.19 0 0 0.16 0 0 0.063333333 0.053333333 7.53 0 0 2.583333333 2.51 0.998591786 -0.016244142 "00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis" GO:0001669///acrosomal vesicle+++GO:0001772///immunological synapse+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle+++GO:0097225///sperm midpiece GO:0001716///L-amino-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002819///regulation of adaptive immune response+++GO:0002841///negative regulation of T cell mediated immune response to tumor cell+++GO:0006559///L-phenylalanine catabolic process+++GO:0006569///tryptophan catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0009063///cellular amino acid catabolic process+++GO:0009072///aromatic amino acid family metabolic process+++GO:0019440///tryptophan catabolic process to indole-3-acetate+++GO:0042130///negative regulation of T cell proliferation+++GO:0045577///regulation of B cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050868///negative regulation of T cell activation 100336 100336 'Ppp1r8' mRNA 467 439 372 12.97 12.01 10.98 11.97 11.38 11.36 11.98666667 11.57 498 459 455 426 470.6666667 0.359702571 0.134651163 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0008380///RNA splicing+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 100340 100340 'Smpdl3b' mRNA 72 78 92 2.14 2.28 3.01 6.02 7.11 6.34 2.476666667 6.49 233 262 234 80.66666667 243 4.70E-14 1.57646401 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane "GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding" GO:0002376///immune system process+++GO:0006629///lipid metabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0016042///lipid catabolic process+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0045087///innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0046466///membrane lipid catabolic process+++GO:0050728///negative regulation of inflammatory response 100342 100342 'Tent5b' mRNA 462 476 172 11.34 11.51 4.48 6.49 10.56 8.49 9.11 8.513333333 304 483 385 370 390.6666667 0.881633091 0.092144042 GO:0005575///cellular_component GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:1990817///RNA adenylyltransferase activity GO:0048255///mRNA stabilization 100383 100383 'Bsdc1' mRNA 982 1032 934 20.35 21.03 20.56 19.55 17.2 18.96 20.64666667 18.57 1085 931 1020 982.6666667 1012 0.810321518 0.030655318 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 100384868 100384868 'Gm37013' mRNA 4.17 13.55 21.22 0.05 0.15 0.26 0 0 0 0.153333333 0 0 0 0 12.98 0 1.39E-04 -6.139787445 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0032592///integral component of mitochondrial membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004949///cannabinoid receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels "GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007413///axonal fasciculation+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0010976///positive regulation of neuron projection development+++GO:0014063///negative regulation of serotonin secretion+++GO:0019216///regulation of lipid metabolic process+++GO:0019222///regulation of metabolic process+++GO:0019233///sensory perception of pain+++GO:0031622///positive regulation of fever generation+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0032496///response to lipopolysaccharide+++GO:0033004///negative regulation of mast cell activation+++GO:0033602///negative regulation of dopamine secretion+++GO:0035094///response to nicotine+++GO:0038171///cannabinoid signaling pathway+++GO:0042220///response to cocaine+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043271///negative regulation of ion transport+++GO:0043278///response to morphine+++GO:0045471///response to ethanol+++GO:0045759///negative regulation of action potential+++GO:0045776///negative regulation of blood pressure+++GO:0045777///positive regulation of blood pressure+++GO:0050796///regulation of insulin secretion+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060135///maternal process involved in female pregnancy+++GO:0060259///regulation of feeding behavior+++GO:0060405///regulation of penile erection+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration" 100415785 100415785 'Gm11559' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 100416706 100416706 'Zfp729b' mRNA 346.59 387.84 362.23 3.84 4.22 4.25 3.38 2.77 2.62 4.103333333 2.923333333 351.3 281.37 263.86 365.5533333 298.8433333 0.061777445 -0.304948704 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070895///negative regulation of transposon integration" 100417514 100417514 'Adh6b' mRNA 1 0 0 0.03 0 0 0.4 0.2 0.26 0.01 0.286666667 15 7 9 0.333333333 10.33333333 0.003138264 4.831286001 GO:0005829///cytosol "GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0004024///alcohol dehydrogenase activity, zinc-dependent+++GO:0004745///retinol dehydrogenase activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding" GO:0006069///ethanol oxidation+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0045471///response to ethanol 100434 100434 'Slc44a1' mRNA 1499 1735 1218 21.06 23.86 17.95 18.61 14.6 18.15 20.95666667 17.12 1620 1249 1536 1484 1468.333333 0.872658433 -0.022791435 05231///Choline metabolism in cancer GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015220///choline transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015871///choline transport+++GO:0055085///transmembrane transport 100463512 100463512 'Gm20594' mRNA 4979 4865 4743 1828.47 1818.24 1857.29 1599.36 1197.23 1634.6 1834.666667 1477.063333 4874 3525 4771 4862.333333 4390 0.114027036 -0.16186673 GO:0048019///receptor antagonist activity GO:1900118///negative regulation of execution phase of apoptosis+++GO:2000272///negative regulation of signaling receptor activity 100465 100465 'Mob3c' mRNA 325 345 315 6.02 6.3 6.28 10.53 10.41 9.57 6.2 10.17 643 626 566 328.3333333 611.6666667 1.63E-13 0.886365312 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0016301///kinase activity+++GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0016310///phosphorylation 100470 100470 'Lao1' mRNA 3 4 3 0.09 0.11 0.09 0.38 0.08 0.5 0.096666667 0.32 15 3 19 3.333333333 12.33333333 0.078724064 1.872099292 "00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis" GO:0005576///extracellular region GO:0001716///L-amino-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity GO:0009063///cellular amino acid catabolic process 100494 100494 'Zfand2a' mRNA 635 714 523 11.22 12.42 9.8 16.18 13.66 15.6 11.14666667 15.14666667 1053 868 983 624 968 2.09E-08 0.625257903 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045047///protein targeting to ER+++GO:0071243///cellular response to arsenic-containing substance 100502590 100502590 'Tex50' mRNA 8 3 6 0.54 0.2 0.43 0 0 0 0.39 0 0 0 0 5.666666667 0 0.010638014 -4.962635958 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100502592 100502592 'Gm4736' mRNA 2 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 100502680 100502680 'Gm10015' mRNA 101.54 107.26 85.65 3.25 3.39 2.91 1.7 1.42 2.11 3.183333333 1.743333333 61.12 49.7 73.27 98.15 61.36333333 0.021358646 -0.687901034 100502698 100502698 'Rubcn' mRNA 856.65 988.91 892.36 8.52 9.83 9.35 8.47 9.28 8.83 9.233333333 8.86 984.94 1016.54 983.79 912.64 995.09 0.3020252 0.11375851 04140///Autophagy - animal GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0010507///negative regulation of autophagy+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0045806///negative regulation of endocytosis+++GO:1901097///negative regulation of autophagosome maturation 100502736 100502736 'Gm19345' mRNA 26.12 40.98 36.56 1.67 2.6 2.49 0.89 0.73 0.68 2.253333333 0.766666667 15.99 12.69 11.81 34.55333333 13.49666667 0.008053057 -1.439444703 100502766 100502766 'Kifc1' mRNA 4.79 6.95 2.37 0.12 0.17 0.06 0.92 0.84 0.68 0.116666667 0.813333333 43.61 39.11 31.52 4.703333333 38.08 1.00E-06 3.230624873 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030139///endocytic vesicle+++GO:0031616///spindle pole centrosome+++GO:0072686///mitotic spindle "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0010826///negative regulation of centrosome duplication+++GO:0047496///vesicle transport along microtubule+++GO:0051301///cell division+++GO:0072382///minus-end-directed vesicle transport along microtubule+++GO:0090307///mitotic spindle assembly 100502803 100502803 'Gm11562' mRNA 0 0 1 0 0 0.09 0.28 0.15 0 0.03 0.143333333 3.74 2 0 0.333333333 1.913333333 0.507005417 2.197804116 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 100502825 100502825 'Rpl37rt' mRNA 45.33 37.21 45.09 4.85 3.96 5.12 2.97 2.98 4.45 4.643333333 3.466666667 31.77 30.96 45.83 42.54333333 36.18666667 0.589342593 -0.274971517 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019838///growth factor binding+++GO:0019843///rRNA binding+++GO:0046872///metal ion binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0006412///translation+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity 100502841 100502841 'Epg5' mRNA 1025.69 1097 902.02 9.69 9.6 8.28 8.26 6.2 7.12 9.19 7.193333333 915 705.58 801 1008.236667 807.1933333 0.002173912 -0.331603398 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0006862///nucleotide transport+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0032456///endocytic recycling+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0097352///autophagosome maturation+++GO:1990786///cellular response to dsDNA 100502846 100502846 'Gm19410' mRNA 4 4 2 0.03 0.03 0.02 0 0 0 0.026666667 0 0 0 0 3.333333333 0 0.076630767 -4.177994948 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0006897///endocytosis+++GO:0048251///elastic fiber assembly 100502861 100502861 'Ccdc13' mRNA 1034 1023 1000 21.3 21.16 22.09 9.23 9.08 9.41 21.51666667 9.24 428 410 441 1019 426.3333333 1.29E-37 -1.26915391 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0042995///cell projection GO:0003674///molecular_function GO:0006974///cellular response to DNA damage stimulus+++GO:0030030///cell projection organization+++GO:0031122///cytoplasmic microtubule organization+++GO:1905515///non-motile cilium assembly 100502876 100502876 'Kcnmb3' mRNA 69 63.99 71.64 0.44 0.4 0.49 0.28 0.24 0.24 0.443333333 0.253333333 49.7 42.89 41.98 68.21 44.85666667 0.069720328 -0.636343369 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015269///calcium-activated potassium channel activity+++GO:0015459///potassium channel regulator activity GO:0001508///action potential+++GO:0005513///detection of calcium ion+++GO:0006813///potassium ion transport+++GO:0019228///neuronal action potential+++GO:0071805///potassium ion transmembrane transport 100502926 100502926 'Gm19457' mRNA 0 1 0 0 0.22 0 0 0 0 0.073333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100502940 100502940 'Colca2' mRNA 277 275 277 13.89 14.39 15.37 6.26 6.84 6.26 14.55 6.453333333 144 151 136 276.3333333 143.6666667 3.28E-08 -0.955950468 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 100502941 100502941 'Gm17353' mRNA 0 0 1 0 0 0.03 0 0.03 0 0.01 0.01 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 100502950 100502950 'Gm3336' mRNA 3 0 1 0.16 0 0.06 0.19 0.09 0.1 0.073333333 0.126666667 4 2 2 1.333333333 2.666666667 0.672434561 0.982461587 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100502955 100502955 'Gm19470' mRNA 52 60 65 1.93 2.2 2.56 0.19 0.3 0.17 2.23 0.22 6 9 5 59 6.666666667 7.38E-10 -3.15998679 100502967 100502967 'Speer4c' mRNA 64.32 90.25 71.86 1.5 2.07 1.77 0.75 0.54 0.81 1.78 0.7 36.88 26.01 38.67 75.47666667 33.85333333 8.95E-04 -1.181206585 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100503014 100503014 'Gm19505' mRNA 1.69 0.95 1.36 0.13 0.07 0.11 0.06 0.07 0.08 0.103333333 0.07 0.93 1 1.09 1.333333333 1.006666667 0.998591786 -0.018390223 100503041 100503041 'Pdzd7' mRNA 516.61 594.55 558.96 6.68 7.76 7.8 1.22 1.17 0.73 7.413333333 1.04 117.33 101.17 67.14 556.7066667 95.21333333 4.61E-48 -2.563099556 GO:0001917///photoreceptor inner segment+++GO:0002141///stereocilia ankle link+++GO:0002142///stereocilia ankle link complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:1990696///USH2 complex GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007605///sensory perception of sound+++GO:0045184///establishment of protein localization+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060117///auditory receptor cell development 100503043 100503043 'Armcx4' mRNA 139.6 102 97.97 0.89 0.65 0.64 0.41 0.37 0.48 0.726666667 0.42 72 64.88 84.01 113.19 73.63 0.027375112 -0.628663759 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 100503085 100503085 'Klhl3' mRNA 444.17 452.39 449.25 3.35 3.41 3.61 1.99 1.71 1.82 3.456666667 1.84 305.47 253.22 272.37 448.6033333 277.02 2.16E-07 -0.710223716 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0003779///actin binding+++GO:0003824///catalytic activity+++GO:0097602///cullin family protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0050801///ion homeostasis+++GO:0070294///renal sodium ion absorption+++GO:0070936///protein K48-linked ubiquitination+++GO:0072156///distal tubule morphogenesis 100503125 100503125 'Gm10913' mRNA 2.11 3.68 0 0.33 0.58 0 0.14 0 0.43 0.303333333 0.19 1 0 3 1.93 1.333333333 0.914197237 -0.302285599 100503185 100503185 'Btbd8' mRNA 159 206 150 1.3 1.62 1.32 0.8 0.74 0.54 1.413333333 0.693333333 105 105 71 171.6666667 93.66666667 2.75E-04 -0.88196766 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0030122///AP-2 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0044297///cell body+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005515///protein binding GO:0006897///endocytosis+++GO:0016182///synaptic vesicle budding from endosome+++GO:0031175///neuron projection development+++GO:0036466///synaptic vesicle recycling via endosome+++GO:0048488///synaptic vesicle endocytosis+++GO:0150007///clathrin-dependent synaptic vesicle endocytosis 100503311 100503311 'Pifo' mRNA 1190 1201 1281 85.9 85.83 98.14 9.45 8.15 10.96 89.95666667 9.52 150 126 168 1224 148 3.67E-128 -3.062912702 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0048487///beta-tubulin binding GO:0030030///cell projection organization+++GO:0031344///regulation of cell projection organization+++GO:0033674///positive regulation of kinase activity+++GO:0044782///cilium organization+++GO:0060971///embryonic heart tube left/right pattern formation 100503353 100503353 'Gm14440' mRNA 247.97 264.6 251.9 4 4.19 4.31 3.19 3.02 2.94 4.166666667 3.05 228.05 210.61 203.42 254.8233333 214.0266667 0.145112201 -0.261943961 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 100503355 100503355 'Zfp648' mRNA 62 89 53 1.12 1.58 1.01 0.42 0.37 0.49 1.236666667 0.426666667 27 23 30 68 26.66666667 4.21E-04 -1.355017481 "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 100503361 100503361 'Tmem95' mRNA 8 3 4 0.44 0.32 0.25 0.39 0.89 0.61 0.336666667 0.63 7 17 12 5 12 0.201010119 1.260912011 GO:0002080///acrosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0097524///sperm plasma membrane GO:0003674///molecular_function GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization 100503368 100503368 'Gm20599' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100503386 100503386 'Tpbgl' mRNA 347 309 91 6.27 5.5 1.74 0.82 0.95 0.5 4.503333333 0.756666667 52 59 31 249 47.33333333 1.52E-04 -2.382433273 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0090090///negative regulation of canonical Wnt signaling pathway 100503388 100503388 'Gm19668' mRNA 0 3 0 0 0.25 0 0 0 0 0.083333333 0 0 0 0 1 0 0.659075281 -2.407827175 GO:0005882///intermediate filament+++GO:0045095///keratin filament 100503545 100503545 'Nuggc' mRNA 1 1 1 0.03 0.02 0.02 0.25 0.23 0.29 0.023333333 0.256666667 13 12 15 1 13.33333333 0.002369664 3.725634182 GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0033262///regulation of nuclear cell cycle DNA replication+++GO:0043066///negative regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide 100503549 100503549 'Gm10354' mRNA 0 3.06 2.97 0 0.18 0.19 0.05 0.11 0.1 0.123333333 0.086666667 1.04 2.09 1.78 2.01 1.636666667 0.897410732 -0.330619823 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100503572 100503572 'Bbip1' mRNA 973.08 915.85 972.48 23.82 21.95 25.3 17.57 17.94 17.11 23.69 17.54 831.31 818.79 796.04 953.8033333 815.38 0.019398864 -0.239600884 GO:0005737///cytoplasm+++GO:0034464///BBSome GO:0003674///molecular_function GO:0042755///eating behavior+++GO:0060271///cilium assembly+++GO:0097500///receptor localization to non-motile cilium 100503583 100503583 'Fsbp' mRNA 37 27 27 0.43 0.31 0.34 0.37 0.21 0.32 0.36 0.3 36 19.9 30.01 30.33333333 28.63666667 0.863090843 -0.112574423 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0042802///identical protein binding GO:0008150///biological_process 100503584 100503584 'Zfp534' mRNA 7.99 9.25 3.99 0.19 0.22 0.11 0.5 0.22 0.24 0.173333333 0.32 24.43 10.75 11.7 7.076666667 15.62666667 0.163558573 1.238164205 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100503605 100503605 'Hbb-bs' mRNA 1741.64 1699.08 1692.54 202.35 196.33 208.73 353.81 377.31 360.2 202.47 363.7733333 3477.04 3605.57 3412.96 1711.086667 3498.523333 3.65E-51 1.020200223 05143///African trypanosomiasis+++05144///Malaria GO:0005615///extracellular space+++GO:0005833///hemoglobin complex+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0030492///hemoglobin binding+++GO:0031720///haptoglobin binding+++GO:0031721///hemoglobin alpha binding+++GO:0031722///hemoglobin beta binding+++GO:0043177///organic acid binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006749///glutathione metabolic process+++GO:0010999///regulation of eIF2 alpha phosphorylation by heme+++GO:0015671///oxygen transport+++GO:0030097///hemopoiesis+++GO:0042744///hydrogen peroxide catabolic process+++GO:0048821///erythrocyte development+++GO:0098869///cellular oxidant detoxification 100503609 100503609 'Lnp1' mRNA 2 0 0 0.17 0 0 0.23 0 0 0.056666667 0.076666667 3 0 0 0.666666667 1 0.888765957 0.566961205 100503659 100503659 'Cbarp' mRNA 426.01 510.26 122.29 7.47 8.76 2.29 2.58 2.49 2.49 6.173333333 2.52 165.09 158.5 159 352.8533333 160.8633333 0.069521358 -1.119808641 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse GO:0044325///ion channel binding GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1903170///negative regulation of calcium ion transmembrane transport 100503670 100503670 'Rpl5' mRNA 3832.57 3841.94 3847.54 176.08 174.97 186.77 241.18 237.13 247.96 179.2733333 242.09 5807.9 5516.94 5768.91 3840.683333 5697.916667 5.90E-21 0.556123851 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0019843///rRNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048027///mRNA 5'-UTR binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0000027///ribosomal large subunit assembly+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0010628///positive regulation of gene expression+++GO:0010922///positive regulation of phosphatase activity+++GO:0042273///ribosomal large subunit biogenesis+++GO:0045727///positive regulation of translation+++GO:0050821///protein stabilization+++GO:0071241///cellular response to inorganic substance+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:1905017///positive regulation of isoleucine-tRNA ligase activity+++GO:1905020///positive regulation of methionine-tRNA ligase activity+++GO:1905023///positive regulation of threonine-tRNA ligase activity+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000435///negative regulation of protein neddylation 100503710 100503710 'Gm5741' mRNA 6 4 5 2.3 1.56 2.04 1.03 0.35 0.71 1.966666667 0.696666667 3 1 2 5 2 0.381530071 -1.341571063 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04810///Regulation of actin cytoskeleton+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 100503884 100503884 'Ccdc149' mRNA 176 169 205 2.87 2.7 3.54 1.21 1.2 1.39 3.036666667 1.266666667 86 82 94 183.3333333 87.33333333 1.35E-06 -1.086456918 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100503890 100503890 'Pet100' mRNA 325.98 314 334.93 16.8 15.98 18.32 16.57 18.28 18.21 17.03333333 17.68666667 368.99 397 392 324.97 385.9966667 0.122074269 0.23729151 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0051082///unfolded protein binding GO:0033617///mitochondrial respiratory chain complex IV assembly 100503915 100503915 'Smpd5' mRNA 34.46 36.03 37.59 1 1.08 1.17 1.14 1.58 1.55 1.083333333 1.423333333 43.46 58.19 58.81 36.02666667 53.48666667 0.174354906 0.560934497 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004620///phospholipase activity+++GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006684///sphingomyelin metabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0046513///ceramide biosynthetic process 100503923 100503923 'LOC100503923' mRNA 2.17 4.69 1.47 0.13 0.28 0.09 0.26 0.35 0.78 0.166666667 0.463333333 5.03 6.61 14.52 2.776666667 8.72 0.142998195 1.842949636 100503924 100503924 'Fcor' mRNA 12 5 27 2.71 1.14 6.48 2.4 3.92 3.54 3.443333333 3.286666667 12 19 17 14.66666667 16 0.926224138 0.088557211 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity "GO:0001659///temperature homeostasis+++GO:0001678///cellular glucose homeostasis+++GO:0006473///protein acetylation+++GO:0009267///cellular response to starvation+++GO:0045444///fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070417///cellular response to cold+++GO:0097009///energy homeostasis" 100503949 100503949 'Zfp965' mRNA 409.74 452.97 420.17 3.98 4.04 4.48 3.68 3.13 3.73 4.166666667 3.513333333 440.5 373.04 412.24 427.6266667 408.5933333 0.645680092 -0.077232497 GO:0005575///cellular_component+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100503964 100503964 'Gm17266' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100503991 100503991 'Acp4' mRNA 2.04 1 0 0.08 0.04 0 0.03 0.03 0.03 0.04 0.03 1.04 1.03 1.04 1.013333333 1.036666667 0.998591786 0.0146739 GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane GO:0003993///acid phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030971///receptor tyrosine kinase binding GO:0007040///lysosome organization+++GO:0010955///negative regulation of protein processing+++GO:0010977///negative regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0042476///odontogenesis+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0120154///negative regulation of ERBB4 signaling pathway+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 100504014 100504014 'Gm15056' mRNA 0 1 3 0 0.43 0.63 0 2.39 0.78 0.353333333 1.056666667 0 7 2 1.333333333 3 0.639239121 1.143133676 100504089 100504089 'Gm20056' mRNA 19.26 13.23 18.35 0.68 0.46 0.69 3.56 4.28 3.81 0.61 3.883333333 115.04 135.19 119.15 16.94666667 123.1266667 2.85E-17 2.871545715 100504112 100504112 'Ccer2' mRNA 3584.68 3670.67 3321.15 214.71 217.89 211.36 47.35 46.77 43.43 214.6533333 45.85 912.16 882.35 808.88 3525.5 867.7966667 4.54E-186 -2.033772183 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100504116 100504116 'Brd3os' mRNA 1151 1174 1055 38.55 38.61 37.34 12.13 10.95 10.54 38.16666667 11.20666667 416 366 351 1126.666667 377.6666667 9.86E-57 -1.588167986 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100504180 100504180 'LOC100504180' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100504195 100504195 'Micalcl' mRNA 37 42 49 0.84 0.96 1.21 0.24 0.12 0.19 1.003333333 0.183333333 12 6 9 42.66666667 9 2.24E-05 -2.265838988 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0031941///filamentous actin GO:0051019///mitogen-activated protein kinase binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation 100504221 100504221 'Efcab8' mRNA 45.83 28.38 34.39 0.39 0.18 0.3 0.15 0.15 0.18 0.29 0.16 26.88 24.26 30.33 36.2 27.15666667 0.413685822 -0.431884387 GO:0005575///cellular_component GO:0005509///calcium ion binding GO:0008150///biological_process 100504234 100504234 'Ccdc170' mRNA 20.95 15.94 23.57 0.22 0.17 0.25 0.23 0.21 0.25 0.213333333 0.23 27.27 24.51 28.99 20.15333333 26.92333333 0.492918508 0.426887097 GO:0005794///Golgi apparatus+++GO:0036064///ciliary basal body GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization 100504239 100504239 'Gm10591' mRNA 43.39 50.23 42.36 3.33 3.81 3.44 0.85 1.19 1.25 3.526666667 1.096666667 12.63 17.34 18.02 45.32666667 15.99666667 0.001088555 -1.529699539 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0003674///molecular_function+++GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006954///inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0043547///positive regulation of GTPase activity+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 100504263 100504263 '2210418O10Rik' mRNA 135.98 183.11 131.94 1.91 2.54 1.94 2.43 1.74 0 2.13 1.39 198.43 139.45 0 150.3433333 112.6266667 0.863090843 -0.429494633 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 100504285 100504285 'Abhd12b' mRNA 57.02 42.18 33.99 1.03 0.75 0.65 0.34 0.44 0.53 0.81 0.436666667 22 27.22 33 44.39666667 27.40666667 0.141809261 -0.690140353 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0004622///lysophospholipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0047372///acylglycerol lipase activity GO:0006660///phosphatidylserine catabolic process+++GO:0052651///monoacylglycerol catabolic process+++GO:0098734///macromolecule depalmitoylation 100504309 100504309 'Smim27' mRNA 133 134 195 49.51 50.78 77.41 30.61 28.58 35.09 59.23333333 31.42666667 92 83 101 154 92 0.003734089 -0.765225873 GO:0016020///membrane+++GO:0016021///integral component of membrane 100504346 100504346 'Gm13304' mRNA 43.39 50.23 42.36 3.33 3.81 3.44 0.85 1.19 1.25 3.526666667 1.096666667 12.63 17.34 18.02 45.32666667 15.99666667 0.001088555 -1.529699539 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0003674///molecular_function+++GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006954///inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0043547///positive regulation of GTPase activity+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 100504446 100504446 'Prr22' mRNA 14 19 21 0.62 0.83 0.99 0.5 0.32 0.32 0.813333333 0.38 13 8 8 18 9.666666667 0.218240375 -0.917761606 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100504491 100504491 'Dcdc2b' mRNA 543.89 611.97 601.09 18.44 21.06 22.4 1.92 2.3 2.33 20.63333333 2.183333333 64 70.2 75.38 585.65 69.86 1.16E-76 -3.082617225 GO:0005815///microtubule organizing center+++GO:0005874///microtubule GO:0003674///molecular_function GO:0008150///biological_process+++GO:0035556///intracellular signal transduction 100504518 100504518 '3425401B19Rik' mRNA 4 3 0 0.04 0.03 0 0.02 0.02 0.02 0.023333333 0.02 2 2 2 2.333333333 2 0.927891807 -0.204630978 GO:0005737///cytoplasm+++GO:0030018///Z disc GO:0003674///molecular_function GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 100504663 100504663 'Atg14' mRNA 574 649 605 9.05 10.07 10.12 6.99 6.48 6.21 9.746666667 6.56 510 462 439 609.3333333 470.3333333 0.001407573 -0.386307385 04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034045///phagophore assembly site membrane+++GO:0035032///phosphatidylinositol 3-kinase complex, class III+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0045335///phagocytic vesicle+++GO:0097629///extrinsic component of omegasome membrane+++GO:0097632///extrinsic component of phagophore assembly site membrane" GO:0005515///protein binding+++GO:0051020///GTPase binding GO:0000045///autophagosome assembly+++GO:0000423///mitophagy+++GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0009267///cellular response to starvation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016236///macroautophagy+++GO:0016240///autophagosome membrane docking+++GO:0042149///cellular response to glucose starvation+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0090207///regulation of triglyceride metabolic process+++GO:0098780///response to mitochondrial depolarisation 100504689 100504689 'Plscr5' mRNA 562 569 594 17.93 18.33 20.87 1.69 1.29 1.75 19.04333333 1.576666667 63 39 62 575 54.66666667 2.98E-78 -3.410355364 GO:0005886///plasma membrane GO:0017128///phospholipid scramblase activity GO:0017121///phospholipid scrambling 100504710 100504710 'Nat8f6' mRNA 7.14 12.43 7.76 0.31 0.53 0.36 0.24 0.4 0.26 0.4 0.3 6.46 10.35 6.62 9.11 7.81 0.847448937 -0.242273386 00480///Glutathione metabolism GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004402///histone acetyltransferase activity+++GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0003401///axis elongation+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0016573///histone acetylation+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0050435///amyloid-beta metabolic process 100504715 100504715 'Tmppe' mRNA 336.44 357.97 343.29 2.59 2.71 2.81 3.56 3.27 3.41 2.703333333 3.413333333 531.97 477.23 493.72 345.9 500.9733333 3.71E-05 0.522191132 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0008150///biological_process 100505386 100505386 'Iqschfp' mRNA 6.56 6.55 10.13 0.15 0.15 0.25 0.12 0.11 0 0.183333333 0.076666667 6.09 5.31 0 7.746666667 3.8 0.452547271 -1.029212227 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0033268///node of Ranvier+++GO:0042995///cell projection+++GO:0043194///axon initial segment GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding GO:0001553///luteinization+++GO:0001822///kidney development+++GO:0006807///nitrogen compound metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008366///axon ensheathment+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0010761///fibroblast migration+++GO:0035332///positive regulation of hippo signaling+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0051494///negative regulation of cytoskeleton organization+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis 100505397 100505397 'Gm20385' mRNA 7.89 17.54 5.45 0.11 0.24 0.08 0.07 0.12 0.16 0.143333333 0.116666667 5.79 10.07 12.71 10.29333333 9.523333333 0.936012214 -0.091893527 100515 100515 'Zfp518b' mRNA 190 188 146 1.49 1.44 1.2 1.2 1.29 1.24 1.376666667 1.243333333 178 186 176 174.6666667 180 0.881313794 0.036482608 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II 100529082 100529082 'Gm11127' mRNA 152.99 167.88 154.32 6.85 7.42 7.33 26.68 24.29 25 7.2 25.32333333 684.54 607.86 620.45 158.3966667 637.6166667 5.92E-51 2.002271811 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002485///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0010977///negative regulation of neuron projection development+++GO:0019882///antigen processing and presentation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0042742///defense response to bacterium+++GO:0048839///inner ear development" 100532 100532 'Rell1' mRNA 998 1229 907 16.84 20.4 16.23 20.44 18.63 20.5 17.82333333 19.85666667 1394 1241 1354 1044.666667 1329.666667 8.54E-04 0.339940742 GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:1900745///positive regulation of p38MAPK cascade 100534273 100534273 'Fer1l5' mRNA 4.13 8.49 6.2 0.03 0.06 0.06 0.16 0.11 0.06 0.05 0.11 21.25 14.97 9.39 6.273333333 15.20333333 0.144081269 1.273992075 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0031410///cytoplasmic vesicle GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0001778///plasma membrane repair+++GO:0002280///monocyte activation involved in immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0006906///vesicle fusion+++GO:0007009///plasma membrane organization+++GO:0007520///myoblast fusion+++GO:0033292///T-tubule organization+++GO:0050765///negative regulation of phagocytosis+++GO:0061025///membrane fusion 100534287 100534287 'Dchs2' mRNA 42 76 62 0.14 0.26 0.23 0.3 0.31 0.28 0.21 0.296666667 93 95 93 60 93.66666667 0.049817667 0.631095343 04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0072006///nephron development+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0098609///cell-cell adhesion 100534296 100534296 'Gm9805' mRNA 4 4 4 0.07 0.07 0.08 0.06 0 0 0.073333333 0.02 4 0 0 4 1.333333333 0.416460876 -1.61943821 100535 100535 'Oas1d' mRNA 0 0 2 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding GO:0001541///ovarian follicle development+++GO:0001542///ovulation from ovarian follicle+++GO:0006006///glucose metabolic process+++GO:0009615///response to virus+++GO:0009790///embryo development+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043086///negative regulation of catalytic activity+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0051259///protein complex oligomerization+++GO:0051348///negative regulation of transferase activity+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 100561 100561 'Slc15a4' mRNA 793.68 896.41 830.09 14.86 16.65 17.01 19.26 19.68 17.98 16.17333333 18.97333333 1125.42 1166.9 1033.54 840.06 1108.62 8.17E-05 0.388601357 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031303///integral component of endosome membrane+++GO:0031901///early endosome membrane+++GO:0036020///endolysosome membrane+++GO:1905103///integral component of lysosomal membrane GO:0005290///L-histidine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015333///peptide:proton symporter activity+++GO:0015647///peptidoglycan transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0071916///dipeptide transmembrane transporter activity GO:0002376///immune system process+++GO:0006857///oligopeptide transport+++GO:0015031///protein transport+++GO:0015817///histidine transport+++GO:0015833///peptide transport+++GO:0015835///peptidoglycan transport+++GO:0033023///mast cell homeostasis+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034161///positive regulation of toll-like receptor 8 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0055085///transmembrane transport+++GO:0070424///regulation of nucleotide-binding oligomerization domain containing signaling pathway+++GO:0070430///positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0089708///L-histidine transmembrane export from vacuole+++GO:0140206///dipeptide import across plasma membrane+++GO:1902600///proton transmembrane transport 100604 100604 'Lrrc8c' mRNA 579 593 504 7.24 7.6 6.93 11.78 11.02 11.36 7.256666667 11.38666667 918 871 917 558.6666667 902 3.39E-12 0.681616365 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034702///ion channel complex GO:0005225///volume-sensitive anion channel activity GO:0006811///ion transport+++GO:0015698///inorganic anion transport+++GO:0015734///taurine transport+++GO:0015810///aspartate transmembrane transport+++GO:0034214///protein hexamerization+++GO:0045444///fat cell differentiation+++GO:0071470///cellular response to osmotic stress+++GO:0098656///anion transmembrane transport 100608 100608 'Noc4l' mRNA 573 627 601 15.97 17.21 17.77 21.74 22.54 21.48 16.98333333 21.92 897 908 858 600.3333333 887.6666667 5.32E-08 0.552255888 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030692///Noc4p-Nop14p complex+++GO:0031965///nuclear membrane+++GO:0032040///small-subunit processome GO:0042254///ribosome biogenesis 100609 100609 'Nsun5' mRNA 487.71 443.71 493.34 12.12 10.78 13.03 10.11 9.27 11.11 11.97666667 10.16333333 467.24 417.17 495.59 474.92 460 0.739670559 -0.059880157 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0009383///rRNA (cytosine-C5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0014003///oligodendrocyte development+++GO:0021987///cerebral cortex development+++GO:0022038///corpus callosum development+++GO:0031641///regulation of myelination+++GO:0032259///methylation+++GO:0045727///positive regulation of translation+++GO:0050890///cognition+++GO:0070475///rRNA base methylation 100637 100637 'N4bp2l1' mRNA 224.63 235.72 197.7 6.75 6.98 6.3 6.88 7.32 8.1 6.676666667 7.433333333 263.18 273.5 299.93 219.35 278.87 0.048560747 0.339538586 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100678 100678 'Psph' mRNA 841 846 796 32.33 31.84 31.63 30.13 30.62 30.16 31.93333333 30.30333333 866 875 859 827.6666667 866.6666667 0.646296338 0.055453713 "00260///Glycine, serine and threonine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043005///neuron projection GO:0000287///magnesium ion binding+++GO:0004647///phosphoserine phosphatase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0036424///L-phosphoserine phosphatase activity+++GO:0036425///D-phosphoserine phosphatase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0006563///L-serine metabolic process+++GO:0006564///L-serine biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009612///response to mechanical stimulus+++GO:0016311///dephosphorylation+++GO:0031667///response to nutrient levels+++GO:0033574///response to testosterone 100683 100683 'Trrap' mRNA 1975 2068 1712 7.98 8.2 7.33 6.67 6.58 6.15 7.836666667 6.466666667 1895 1829 1697 1918.333333 1807 0.283281747 -0.095248647 05166///Human T-cell leukemia virus 1 infection GO:0000123///histone acetyltransferase complex+++GO:0000124///SAGA complex+++GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005794///Golgi apparatus+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0035267///NuA4 histone acetyltransferase complex GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007093///mitotic cell cycle checkpoint+++GO:0016310///phosphorylation+++GO:0016573///histone acetylation+++GO:0016578///histone deubiquitination+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045893///positive regulation of transcription, DNA-templated" 100689 100689 'Spon2' mRNA 103 147 105 2.71 3.88 3.06 3.58 4.35 3.89 3.216666667 3.94 147 182 167 118.3333333 165.3333333 0.047669467 0.476601939 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0001530///lipopolysaccharide binding+++GO:0003823///antigen binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0002448///mast cell mediated immunity+++GO:0007155///cell adhesion+++GO:0008228///opsonization+++GO:0032496///response to lipopolysaccharide+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042742///defense response to bacterium+++GO:0043152///induction of bacterial agglutination+++GO:0045087///innate immune response+++GO:0050832///defense response to fungus+++GO:0051607///defense response to virus+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0071222///cellular response to lipopolysaccharide 100702 100702 'Gbp6' mRNA 901.1 964.23 877.84 11.2 11.78 11.57 19.14 18.25 17.22 11.51666667 18.20333333 1772.49 1651.22 1542.74 914.39 1655.483333 1.59E-24 0.844948023 GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0009617///response to bacterium+++GO:0035458///cellular response to interferon-beta+++GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma 100705 100705 'Acacb' mRNA 455 436 341 2.82 2.65 2.23 2.12 1.77 2.28 2.566666667 2.056666667 391 315 407 410.6666667 371 0.373375966 -0.154717877 00061///Fatty acid biosynthesis+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003989///acetyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0009374///biotin binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0008152///metabolic process+++GO:0010629///negative regulation of gene expression+++GO:0010884///positive regulation of lipid storage+++GO:0010906///regulation of glucose metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0031667///response to nutrient levels+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0042493///response to drug+++GO:0043086///negative regulation of catalytic activity+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051289///protein homotetramerization+++GO:0060421///positive regulation of heart growth+++GO:0097009///energy homeostasis+++GO:2001295///malonyl-CoA biosynthetic process 100710 100710 'Pds5b' mRNA 777 899 821 5.63 6.39 6.3 3.69 3.74 3.96 6.106666667 3.796666667 589 583 611 832.3333333 594.3333333 2.57E-06 -0.497374375 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0002088///lens development in camera-type eye+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008285///negative regulation of cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0051301///cell division+++GO:0097402///neuroblast migration 100715 100715 'Tent2' mRNA 715.06 656.13 624.41 10.79 9.76 10.03 15.1 16 15.69 10.19333333 15.59666667 1145 1182.36 1150.01 665.2 1159.123333 8.74E-18 0.791180804 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0034062///5'-3' RNA polymerase activity+++GO:0046872///metal ion binding+++GO:0070566///adenylyltransferase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0021766///hippocampus development+++GO:0030182///neuron differentiation+++GO:0031123///RNA 3'-end processing+++GO:0043489///RNA stabilization+++GO:0043631///RNA polyadenylation+++GO:0060041///retina development in camera-type eye+++GO:0071044///histone mRNA catabolic process+++GO:1990603///dark adaptation+++GO:2000626///negative regulation of miRNA catabolic process 100732 100732 'Mapre3' mRNA 2271 2229 2044 71.15 68.82 67.77 38.19 38.89 36.85 69.24666667 37.97666667 1405 1386 1307 2181.333333 1366 5.23E-22 -0.68579014 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0035371///microtubule plus-end+++GO:0048471///perinuclear region of cytoplasm+++GO:0051233///spindle midzone+++GO:1905721///mitotic spindle astral microtubule end GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0051010///microtubule plus-end binding "GO:0007049///cell cycle+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031113///regulation of microtubule polymerization+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:1903033///positive regulation of microtubule plus-end binding+++GO:1904825///protein localization to microtubule plus-end" 100737 100737 'Dcun1d4' mRNA 728.41 821.73 792.84 8.92 9.85 10.37 6.68 6.69 6.31 9.713333333 6.56 658.11 618.25 606.35 780.9933333 627.57 0.00280163 -0.327993042 GO:0000151///ubiquitin ligase complex+++GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032182///ubiquitin-like protein binding+++GO:0097602///cullin family protein binding GO:0008150///biological_process+++GO:0045116///protein neddylation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000436///positive regulation of protein neddylation 100756 100756 'Usp30' mRNA 399 359 264 6.75 5.94 4.76 3.02 3.01 3.33 5.816666667 3.12 217 205 214 340.6666667 212 5.20E-05 -0.689777025 04137///Mitophagy - animal GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0000422///autophagy of mitochondrion+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0008053///mitochondrial fusion+++GO:0016579///protein deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0044313///protein K6-linked deubiquitination+++GO:1901525///negative regulation of mitophagy 100763 100763 'Ube3c' mRNA 469 410 474 4.98 4.28 5.34 5.87 5.07 5.13 4.866666667 5.356666667 637 537 539 451 571 0.017484186 0.324332268 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 100764 100764 'Rita1' mRNA 390 395 377 14.17 14.25 14.46 8.74 9.93 8.43 14.29333333 9.033333333 275 301 254 387.3333333 276.6666667 6.87E-04 -0.496369958 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0015631///tubulin binding GO:0007219///Notch signaling pathway+++GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0051168///nuclear export 100855 100855 'Tbc1d14' mRNA 2020 1936 2103 25.65 24.08 28.4 21.31 20.2 21.76 26.04333333 21.09 1954 1824 1947 2019.666667 1908.333333 0.308906753 -0.096453135 GO:0005654///nucleoplasm+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0005096///GTPase activator activity+++GO:0019901///protein kinase binding GO:0006886///intracellular protein transport+++GO:0010507///negative regulation of autophagy+++GO:0071955///recycling endosome to Golgi transport+++GO:0090630///activation of GTPase activity+++GO:2000785///regulation of autophagosome assembly 100859931 100859931 'Gm20604' mRNA 329.95 341.3 358.52 4.65 4.74 5.36 4.51 4.85 5.49 4.916666667 4.95 368.09 386.24 433.56 343.2566667 395.9633333 0.230285008 0.194543902 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 100861615 100861615 'Gm3411' mRNA 10.25 10.74 7.46 0.29 0.3 0.23 0.16 0.38 0.17 0.273333333 0.236666667 6.42 14.72 6.79 9.483333333 9.31 0.964519013 -0.053745013 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100861640 100861640 'Rhox4a2' mRNA 29.07 40.79 33.78 2.26 3 2.66 1.48 1.59 1.81 2.64 1.626666667 22.81 23.82 26.98 34.54666667 24.53666667 0.306991965 -0.532572774 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 100861651 100861651 'Gm9595' mRNA 8.26 18.89 15.91 0.15 0.34 0.3 0.22 0.17 0.16 0.263333333 0.183333333 13.73 10.65 9.81 14.35333333 11.39666667 0.691360852 -0.373334192 100861668 100861668 'Gm21119' mRNA 3909.36 3701.71 3497.44 14.87 13.76 14.11 7.61 6.36 7.64 14.24666667 7.203333333 2316.88 1891.45 2251.76 3702.836667 2153.363333 2.71E-26 -0.794592052 100861686 100861686 'Gm21136' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 100861702 100861702 'Gm21149' mRNA 1.12 4.64 3.78 0.06 0.23 0.2 0.27 0.1 0.06 0.163333333 0.143333333 6.29 2.14 1.38 3.18 3.27 0.942313116 0.144771519 100861708 100861708 'Gm21154' mRNA 0 1 1 0 0.03 0.03 0.08 0.06 0.03 0.02 0.056666667 3 2 1 0.666666667 2 0.561679237 1.559183633 100861753 100861753 'Gm21188' mRNA 60 54.97 41.05 1.99 1.8 1.45 38.51 38.28 40.69 1.746666667 39.16 1327.55 1287.35 1351.4 52.00666667 1322.1 8.26E-212 4.667699168 GO:0038023///signaling receptor activity 100861755 100861755 'Gm21190' mRNA 33.03 22.6 12.76 1.75 1.18 0.72 1.17 1.49 1.84 1.216666667 1.5 25.3 31.52 38.51 22.79666667 31.77666667 0.419208957 0.491280111 100861908 100861908 'Gm21319' mRNA 4.97 0 0 0.15 0 0 0.03 0 0.05 0.05 0.026666667 1.01 0 1.94 1.656666667 0.983333333 0.793137841 -0.996855379 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043023///ribosomal large subunit binding GO:0006412///translation+++GO:0006413///translational initiation 100861973 100861973 'Gm21366' mRNA 0 0.2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.066666667 0 100862066 100862066 'Cfap99' mRNA 196.59 181.83 173.06 2.83 2.57 2.12 0.5 0.47 0.47 2.506666667 0.48 65.7 64.89 62.95 183.8266667 64.51333333 6.36E-12 -1.536811571 100862072 100862072 'Gm21451' mRNA 3.34 3.92 0 0.03 0.06 0 0.87 0.28 0.71 0.03 0.62 57.31 16.9 41.83 2.42 38.68 8.02E-07 4.239504445 100862085 100862085 'Gm16867' mRNA 9.4 4.07 1.01 0.24 0.07 0.02 0.18 0.01 0.2 0.11 0.13 7.14 1.02 7.19 4.826666667 5.116666667 0.952586942 0.100750165 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane GO:0005381///iron ion transmembrane transporter activity GO:0048250///iron import into the mitochondrion+++GO:0055072///iron ion homeostasis 100862177 100862177 'Ccl21d' mRNA 47.18 53.44 42.99 3.41 3.88 3.46 0.86 1.2 1.3 3.583333333 1.12 13.28 17.96 20.59 47.87 17.27666667 9.13E-04 -1.512277669 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001768///establishment of T cell polarity+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002407///dendritic cell chemotaxis+++GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031529///ruffle organization+++GO:0031640///killing of cells of other organism+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0034695///response to prostaglandin E+++GO:0035759///mesangial cell-matrix adhesion+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051491///positive regulation of filopodium assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090630///activation of GTPase activity+++GO:1903237///negative regulation of leukocyte tethering or rolling+++GO:2000147///positive regulation of cell motility+++GO:2000529///positive regulation of myeloid dendritic cell chemotaxis+++GO:2000669///negative regulation of dendritic cell apoptotic process 100862203 100862203 'Gm6712' mRNA 305.39 293.19 312.51 8.66 8.19 9.4 5.89 5.99 5.58 8.75 5.82 238.76 237.18 218.85 303.6966667 231.5966667 0.012946917 -0.406537892 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 100862247 100862247 'Gm21586' mRNA 3.29 3.01 1 0.65 0.23 0.08 0.2 1.09 0.07 0.32 0.453333333 3 5.43 1 2.433333333 3.143333333 0.863090843 0.370174788 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway 100862261 100862261 'Fam205a3' mRNA 98.09 92.52 62.97 0.88 0.82 0.62 0.41 0.35 0.38 0.773333333 0.38 54.89 47.32 51.89 84.52666667 51.36666667 0.023801172 -0.734353677 GO:0016020///membrane+++GO:0016021///integral component of membrane 100862349 100862349 'Gm21663' mRNA 14.4 46.92 42.54 0.27 0.85 0.83 0.11 0 0.11 0.65 0.073333333 6.75 0 6.57 34.62 4.44 7.21E-05 -3.112510303 100862359 100862359 'Gm21671' mRNA 1.97 0 0 0.17 0 0 0 0 0 0.056666667 0 0 0 0 0.656666667 0 0.863090843 -0.97353728 100862365 100862365 'Gm21677' mRNA 0 0 0.11 0 0 0 0 0 0.01 0 0.003333333 0 0 0.29 0.036666667 0.096666667 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0003723///RNA binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100862368 100862368 'Gm21680' mRNA 24.2 33.97 31.82 0.69 0.95 0.96 0.04 0.03 0.05 0.866666667 0.04 1.79 1 2.01 29.99666667 1.6 2.39E-06 -4.472759738 100862375 100862375 'Entpd4b' mRNA 2727.47 2906 2085.58 49.45 51.88 40.1 22 22.01 23.65 47.14333333 22.55333333 1393.59 1361.95 1452.84 2573.016667 1402.793333 1.81E-22 -0.880979632 00230///Purine metabolism+++00240///Pyrimidine metabolism+++04142///Lysosome GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0030173///integral component of Golgi membrane+++GO:0097637///integral component of autophagosome membrane GO:0004382///guanosine-diphosphatase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0036384///cytidine diphosphatase activity+++GO:0043273///CTPase activity+++GO:0045134///uridine-diphosphatase activity GO:0006256///UDP catabolic process+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0046036///CTP metabolic process+++GO:0046712///GDP catabolic process 100862383 100862383 'Gm21693' mRNA 0 0 0.11 0 0 0 0 0 0 0 0 0 0 0 0.036666667 0 GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100862388 100862388 'Gm21698' mRNA 126.43 111.24 81.56 2.32 2.01 1.59 0.13 0.08 0.08 1.973333333 0.096666667 8.15 5.21 4.58 106.41 5.98 3.63E-19 -4.23189191 100862394 100862394 'Gm21704' mRNA 0 0 0.11 0 0 0 0 0 0.01 0 0.003333333 0 0 0.29 0.036666667 0.096666667 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0003723///RNA binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100862398 100862398 'Gm21708' mRNA 0 0 0.11 0 0 0 0 0 0.01 0 0.003333333 0 0 0.29 0.036666667 0.096666667 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 100900 100900 'Hscb' mRNA 130 152 126 11.81 13.41 12.02 18.88 21.34 20.46 12.41333333 20.22666667 247 268 256 136 257 4.76E-07 0.909239164 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0016226///iron-sulfur cluster assembly+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0050790///regulation of catalytic activity+++GO:0051259///protein complex oligomerization+++GO:0097428///protein maturation by iron-sulfur cluster transfer 100910 100910 'Chpf2' mRNA 929.42 899.75 824.13 9.92 9.98 9.42 13.54 15.56 13.89 9.773333333 14.33 1251.5 1378.35 1209.46 884.4333333 1279.77 1.66E-08 0.523811523 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity GO:0030206///chondroitin sulfate biosynthetic process 100929 100929 'Tyw1' mRNA 603 723 702 10.91 12.75 13.29 9.91 10.62 10.49 12.31666667 10.34 615 665 644 676 641.3333333 0.550874606 -0.088436226 "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0010181///FMN binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0102521///tRNA-4-demethylwyosine synthase activity" GO:0008033///tRNA processing+++GO:0031591///wybutosine biosynthetic process 100952 100952 'Emilin1' mRNA 425 408 370 6.64 6.27 6.12 32.7 30.92 29.24 6.343333333 30.95333333 2410 2226 2086 401 2240.666667 1.15E-174 2.471276278 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0034668///integrin alpha4-beta1 complex+++GO:0062023///collagen-containing extracellular matrix+++GO:1990971///EMILIN complex GO:0005515///protein binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0042802///identical protein binding+++GO:0098640///integrin binding involved in cell-matrix adhesion GO:0003180///aortic valve morphogenesis+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0048251///elastic fiber assembly+++GO:0050866///negative regulation of cell activation+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:1904027///negative regulation of collagen fibril organization+++GO:1905522///negative regulation of macrophage migration 100972 100972 'Rab28' mRNA 1688 1775 1742 59.02 61.19 64.62 43.23 48.43 47.7 61.61 46.45333333 1416 1552 1517 1735 1495 0.009751476 -0.226388486 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0035253///ciliary rootlet+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006886///intracellular protein transport+++GO:1901998///toxin transport 100978 100978 'Nfxl1' mRNA 209 222 106 3.11 3.29 1.66 3.6 3.34 3.22 2.686666667 3.386666667 280 254 243 179 259 0.022567673 0.533657752 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 100986 100986 'Akap9' mRNA 5547.89 5563.09 5259.28 22.59 22.33 22.83 9.16 8.74 8.72 22.58333333 8.873333333 2629.01 2456.01 2432.49 5456.753333 2505.836667 2.22E-89 -1.134617412 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005801///cis-Golgi network+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0008076///voltage-gated potassium channel complex+++GO:0034705///potassium channel complex+++GO:0036064///ciliary basal body+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044307///dendritic branch+++GO:0097060///synaptic membrane+++GO:0097729///9+2 motile cilium+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0044325///ion channel binding+++GO:0060090///molecular adaptor activity GO:0007020///microtubule nucleation+++GO:0007165///signal transduction+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007283///spermatogenesis+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031503///protein-containing complex localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034629///cellular protein-containing complex localization+++GO:0051602///response to electrical stimulus+++GO:0051661///maintenance of centrosome location+++GO:0060009///Sertoli cell development+++GO:0060306///regulation of membrane repolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071320///cellular response to cAMP+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1903358///regulation of Golgi organization 101023 101023 'Zfp513' mRNA 130 152 103 3.53 4.12 3.13 3.39 3.5 3.32 3.593333333 3.403333333 143 140 132 128.3333333 138.3333333 0.735333146 0.102287845 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060041///retina development in camera-type eye" 101055663 101055663 'LOC101055663' mRNA 2.97 0 0 0.2 0 0 0.46 0.16 0.48 0.066666667 0.366666667 9.05 2.6 9.01 0.99 6.886666667 0.063092642 3.313913622 101055670 101055670 'Heatr4' mRNA 1 2 1 0.02 0.03 0.02 0.01 0.01 0 0.023333333 0.006666667 1 1 0 1.333333333 0.666666667 0.752606026 -1.004745478 GO:0005575///cellular_component GO:0016491///oxidoreductase activity 101055671 101055671 'Lipo2' mRNA 35.12 27.51 43.82 0.69 0.53 0.91 0.48 0.43 0.45 0.71 0.453333333 27.97 24.56 27.54 35.48333333 26.69 0.398327204 -0.449708952 GO:0043231///intracellular membrane-bounded organelle "GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds" GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process 101055672 101055672 'LOC101055672' mRNA 7.37 2.09 4.79 0.29 0.05 0.12 0.9 0.93 0.97 0.153333333 0.933333333 35.78 32.78 38.01 4.75 35.52333333 6.19E-06 3.001505627 101055676 101055676 'LOC101055676' mRNA 455.85 439.91 345.37 19.63 18.69 15.78 2.76 2.03 2.39 18.03333333 2.393333333 73.47 52.82 61.74 413.71 62.67666667 1.13E-47 -2.744429426 101055745 101055745 'Gm29721' mRNA 15.2 19.43 13.62 0.88 1.19 0.85 0 0.36 0.11 0.973333333 0.156666667 0 6.16 2.66 16.08333333 2.94 0.011302294 -2.549114064 101055754 101055754 'Gm2974' mRNA 0 0 1 0 0 0.07 0.05 0 0 0.023333333 0.016666667 1.08 0 0 0.333333333 0.36 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 101055758 101055758 'Gm7592' mRNA 19.09 21.41 8.75 0.46 0.53 0.24 2.43 1.98 2.39 0.41 2.266666667 104.95 94.47 121.55 16.41666667 106.99 2.25E-13 2.730523166 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 101055813 101055813 'Gm29726' mRNA 0.73 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 0.243333333 0 101055854 101055854 'Gm29733' mRNA 16 13 10 3.68 3.01 2.44 1.83 2.1 1.91 3.043333333 1.946666667 9 10 9 13 9.333333333 0.595412257 -0.483140895 04714///Thermogenesis 101055907 101055907 'Gm15246' mRNA 144 123 160 2.72 2.06 3.01 0.53 0.53 0.43 2.596666667 0.496666667 34 29 31 142.3333333 31.33333333 2.79E-14 -2.201656087 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 101055909 101055909 'Gm10320' mRNA 62.98 50.99 42.19 11.31 9.17 8.05 19.13 25.9 22.73 9.51 22.58666667 121.03 158.88 138.29 52.05333333 139.4 1.35E-07 1.43165463 GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0031204///posttranslational protein targeting to membrane, translocation" 101055915 101055915 'Gm14438' mRNA 5.06 12.18 6.68 0.32 0.76 0.44 0 0.15 0 0.506666667 0.05 0 2.72 0 7.973333333 0.906666667 0.03458962 -3.516364002 101055939 101055939 'Kif19b' mRNA 0 2 2 0 0.02 0.04 0.01 0 0.01 0.02 0.006666667 1 0 1 1.333333333 0.666666667 0.760045476 -1.033175576 GO:0005871///kinesin complex+++GO:0005874///microtubule "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement 101055956 101055956 'Gm29753' mRNA 1 3 6 0.1 0.31 0.66 0.73 0.37 0.19 0.356666667 0.43 8 4 2 3.333333333 4.666666667 0.800647952 0.44291138 101055983 101055983 'Gm14569' mRNA 14 12 5 0.11 0.09 0.04 0.02 0.01 0.02 0.08 0.016666667 3 1 3 10.33333333 2.333333333 0.05983149 -2.146375202 GO:0001669///acrosomal vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0061832///basal ectoplasmic specialization 101055987 101055987 'Gm29758' mRNA 5.19 4.01 5.39 0.21 0.16 0.23 0.33 0.23 0.28 0.2 0.28 9.48 6.42 7.54 4.863333333 7.813333333 0.60781187 0.634283387 101056017 101056017 'Gm28802' mRNA 0 0 2 0 0 0.05 0 0.02 0.02 0.016666667 0.013333333 0 1 1 0.666666667 0.666666667 0.995604954 -0.060645737 101056029 101056029 'Gm7206' mRNA 4.4 8.05 6.24 0.43 0.77 0.64 0.24 0.61 1.78 0.613333333 0.876666667 2.86 7.01 20.31 6.23 10.06 0.580642727 0.68538794 101056047 101056047 'Gm28455' mRNA 21.37 12.1 23.03 0.33 0.18 0.37 0.17 0.25 0.27 0.293333333 0.23 12.8 18.3 20.1 18.83333333 17.06666667 0.834051226 -0.181014327 101056073 101056073 'Zfp990' mRNA 57.82 74.53 65.02 1.37 1.86 1.68 3.9 3.41 4.04 1.636666667 3.783333333 187.75 157.61 185.37 65.79 176.91 1.12E-09 1.419970643 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 101056075 101056075 'Gm16510' mRNA 2 3 4 0.5 0.76 1.07 0.22 0.23 0.23 0.776666667 0.226666667 1 1 1 3 1 0.431378526 -1.607066115 101056084 101056084 'Gm29776' mRNA 17 27 22 0.26 0.54 0.44 0.36 0.26 0.2 0.413333333 0.273333333 28 16 16 22 20 0.84906881 -0.153625991 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007155///cell adhesion 101056100 101056100 'Gm7094' mRNA 2.65 2.53 4.97 0.23 0.22 0.45 0.09 0.09 0.1 0.3 0.093333333 1.21 1.13 1.24 3.383333333 1.193333333 0.503587441 -1.443241801 101056159 101056159 'Gm8104' mRNA 3 1.05 1 0.1 0.03 0.04 0 0 0 0.056666667 0 0 0 0 1.683333333 0 0.334169217 -3.181769893 101056205 101056205 'Gm29797' mRNA 13 14 12 0.2 0.21 0.19 0.09 0.1 0 0.2 0.063333333 7 5 0 13 4 0.095068159 -1.715649039 101056240 101056240 'Gm13430' mRNA 18.27 16.28 22.49 1.33 1.17 1.74 1.11 1.28 1.74 1.413333333 1.376666667 17.53 19.69 26.49 19.01333333 21.23666667 0.863090843 0.130551415 03013///Nucleocytoplasmic transport+++05418///Fluid shear stress and atherosclerosis 101056241 101056241 'Gm29808' mRNA 5.01 5.01 3 0.2 0.19 0.13 0.18 0.14 0.14 0.173333333 0.153333333 5.19 4.01 4 4.34 4.4 0.998591786 -0.005044859 101095 101095 'Zfp282' mRNA 503 549 434 5.22 5.53 4.77 4.31 3.68 4.04 5.173333333 4.01 476 402 434 495.3333333 437.3333333 0.176502092 -0.189036537 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 101100 101100 'Ttll3' mRNA 2439.61 2464.78 2326.31 57.12 59 58.88 6.34 6.47 5.58 58.33333333 6.13 319.1 292.5 272.95 2410.233333 294.85 3.60E-262 -3.045305084 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0036126///sperm flagellum+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0070735///protein-glycine ligase activity+++GO:0070736///protein-glycine ligase activity, initiating" GO:0006464///cellular protein modification process+++GO:0018094///protein polyglycylation+++GO:0030317///flagellated sperm motility+++GO:0035082///axoneme assembly+++GO:0060271///cilium assembly 101113 101113 'Snx21' mRNA 827.64 918.95 819.18 26.57 28.54 28.12 20.12 21.85 21.59 27.74333333 21.18666667 707.35 753.36 731.78 855.2566667 730.83 0.02405672 -0.236936716 GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:1901981///phosphatidylinositol phosphate binding" GO:0008150///biological_process+++GO:0015031///protein transport 101118 101118 'Tmem168' mRNA 883 897 1042 11.15 11.08 13.88 11.74 11.61 11.37 12.03666667 11.57333333 1066 1043 1013 940.6666667 1040.666667 0.303812415 0.129292162 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle GO:0003674///molecular_function GO:0008150///biological_process 101122 101122 'Rpusd3' mRNA 384 309 323 18.4 14.62 16.42 8.68 11.17 10.58 16.48 10.14333333 208 261 245 338.6666667 238 0.002488527 -0.518532304 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0006397///mRNA processing+++GO:0009451///RNA modification+++GO:0070131///positive regulation of mitochondrial translation 101142 101142 'Itfg2' mRNA 744.94 656.64 648.76 18.19 15.79 16.8 11.24 10.75 10.8 16.92666667 10.93 529.16 494.34 492.64 683.4466667 505.38 7.51E-05 -0.446561251 GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0140007///KICSTOR complex GO:0003674///molecular_function GO:0002314///germinal center B cell differentiation+++GO:0032006///regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:1904262///negative regulation of TORC1 signaling 101148 101148 'Bmt2' mRNA 292 321 299 3.8 4.11 4.13 2.61 3.16 3.64 4.013333333 3.136666667 231 273 312 304 272 0.383194578 -0.170277764 GO:0005730///nucleolus+++GO:0140007///KICSTOR complex+++GO:1990130///GATOR1 complex GO:0008168///methyltransferase activity+++GO:0016433///rRNA (adenine) methyltransferase activity+++GO:0016740///transferase activity+++GO:1904047///S-adenosyl-L-methionine binding GO:0032259///methylation+++GO:0034198///cellular response to amino acid starvation+++GO:1904262///negative regulation of TORC1 signaling 101185 101185 'Pot1a' mRNA 667 628 643 12.5 11.57 12.76 8.04 8.74 6.88 12.27666667 7.886666667 493 525 410 646 476 4.16E-04 -0.452882751 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0070187///shelterin complex" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0042162///telomeric DNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0061821///telomeric D-loop binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:1990955///G-rich single-stranded DNA binding GO:0000723///telomere maintenance+++GO:0007004///telomere maintenance via telomerase+++GO:0016233///telomere capping+++GO:0031627///telomeric loop formation+++GO:0032202///telomere assembly+++GO:0032210///regulation of telomere maintenance via telomerase+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032508///DNA duplex unwinding+++GO:0051096///positive regulation of helicase activity+++GO:0051276///chromosome organization+++GO:0051973///positive regulation of telomerase activity+++GO:0051974///negative regulation of telomerase activity+++GO:0060383///positive regulation of DNA strand elongation+++GO:0061820///telomeric D-loop disassembly+++GO:0070200///establishment of protein localization to telomere+++GO:1905774///regulation of DNA helicase activity+++GO:1905776///positive regulation of DNA helicase activity+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 101187 101187 'Parp11' mRNA 362.47 364.74 364.74 5.5 5.5 5.83 5.93 5.74 4.95 5.61 5.54 464.5 430.84 373.14 363.9833333 422.8266667 0.181983075 0.203775435 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity" GO:0006471///protein ADP-ribosylation+++GO:0006998///nuclear envelope organization+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0051028///mRNA transport+++GO:0070213///protein auto-ADP-ribosylation 101197 101197 'Zfp956' mRNA 550 550 490 11.01 10.84 10.4 6.54 5.77 5.62 10.75 5.976666667 376 324 313 530 337.6666667 1.58E-07 -0.661613205 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 101202 101202 'Hepacam2' mRNA 1 2 6 0.03 0.05 0.23 0.14 0.11 0.1 0.103333333 0.116666667 7 4 4 3 5 0.671660644 0.692415003 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051301///cell division 101206 101206 'Tada3' mRNA 814 822 860 21.25 21.49 23.52 16.7 17.86 17.93 22.08666667 17.49666667 697 749 736 832 727.3333333 0.067662788 -0.206827218 05165///Human papillomavirus infection GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0072686///mitotic spindle GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0019904///protein domain specific binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0000278///mitotic cell cycle+++GO:0001932///regulation of protein phosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0031063///regulation of histone deacetylation+++GO:0031647///regulation of protein stability+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation" 101214 101214 'Tra2a' mRNA 806 779 621 23.76 22.47 19.21 25.47 20.37 22.48 21.81333333 22.77333333 969 761 840 735.3333333 856.6666667 0.086719705 0.210997542 03040///Spliceosome+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 101240 101240 'Wdr91' mRNA 286 269 329 6.02 5.57 7.34 8.03 8.67 8.71 6.31 8.47 439 463 461 294.6666667 454.3333333 4.37E-05 0.609113303 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane GO:0035014///phosphatidylinositol 3-kinase regulator activity GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045022///early endosome to late endosome transport+++GO:1903362///regulation of cellular protein catabolic process 101314 101314 'Brk1' mRNA 2676 2713 2630 152.98 153.27 159.53 205.13 211.42 200.81 155.26 205.7866667 4116 4136 3895 2673 4049 6.24E-21 0.587221999 04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0031209///SCAR complex GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001701///in utero embryonic development+++GO:0007015///actin filament organization+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0008284///positive regulation of cell proliferation+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016601///Rac protein signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0048870///cell motility+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 101320 101320 'Dyrk4' mRNA 0 0 3 0 0 0.09 0 0 0.03 0.03 0.01 0 0 1 1 0.333333333 0.734135213 -1.5620629 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation 101351 101351 'Eogt' mRNA 737 857 748 9.33 10.6 10.01 11.48 11.16 10.16 9.98 10.93333333 1032 974 882 780.6666667 962.6666667 0.005674585 0.291065811 00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen "GO:0016262///protein N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0097363///protein O-GlcNAc transferase activity" GO:0006493///protein O-linked glycosylation+++GO:0097370///protein O-GlcNAcylation via threonine 101358 101358 'Fbxl14' mRNA 194 203 167 2.48 2.55 2.26 2.64 2.19 3 2.43 2.61 238 193 262 188 231 0.157149676 0.287366109 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 101359 101359 'Prrt4' mRNA 6 10 3 0.1 0.16 0.05 0.24 0.59 0.33 0.103333333 0.386666667 19 45 25 6.333333333 29.66666667 0.001264804 2.236605686 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 101401 101401 'Adamts9' mRNA 126 118 89 0.76 0.7 0.57 0.88 0.56 0.83 0.676666667 0.756666667 161 102 146 111 136.3333333 0.313629361 0.287044211 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0003179///heart valve morphogenesis+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0006508///proteolysis+++GO:0009617///response to bacterium+++GO:0010596///negative regulation of endothelial cell migration+++GO:0030198///extracellular matrix organization+++GO:0035909///aorta morphogenesis+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0048070///regulation of developmental pigmentation+++GO:0090673///endothelial cell-matrix adhesion+++GO:1903671///negative regulation of sprouting angiogenesis 101437 101437 'Dhx32' mRNA 1713.48 1715.06 1568.88 31.72 31.6 31.21 21.52 23.71 22.81 31.51 22.68 1327.06 1424.64 1363.32 1665.806667 1371.673333 2.90E-04 -0.290033538 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 101471 101471 'Phrf1' mRNA 1308.34 1323 1419 12.99 12.97 14.89 11.74 11.83 11.06 13.61666667 11.54333333 1369.26 1333.68 1246.01 1350.113333 1316.316667 0.670431482 -0.051416809 GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding+++GO:0070063///RNA polymerase binding GO:0006366///transcription by RNA polymerase II+++GO:0006397///mRNA processing 101476 101476 'Plekha1' mRNA 1010 1037 904 14.73 15.17 14.11 14.49 15.17 15.88 14.67 15.18 1139 1155 1200 983.6666667 1164.666667 0.009424398 0.23431167 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane "GO:0008289///lipid binding+++GO:0030165///PDZ domain binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0001553///luteinization+++GO:0007283///spermatogenesis+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0031529///ruffle organization+++GO:0033327///Leydig cell differentiation+++GO:0035264///multicellular organism growth+++GO:0045184///establishment of protein localization+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0050853///B cell receptor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0070301///cellular response to hydrogen peroxide 101488 101488 'Slco2b1' mRNA 520 517 516 6.39 6.66 7.22 11.28 10.98 11.35 6.756666667 11.20333333 1000 956 970 517.6666667 975.3333333 1.37E-20 0.901443352 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity GO:0001889///liver development+++GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0015721///bile acid and bile salt transport+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport+++GO:0071718///sodium-independent icosanoid transport 101488143 101488143 'Hbb-bt' mRNA 306.36 290.92 287.46 36.33 34.32 36.19 69.5 77.52 74.15 35.61333333 73.72333333 668.96 725.43 688.04 294.9133333 694.1433333 7.43E-25 1.226009008 05143///African trypanosomiasis+++05144///Malaria GO:0005615///extracellular space+++GO:0005833///hemoglobin complex+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0030492///hemoglobin binding+++GO:0031720///haptoglobin binding+++GO:0031721///hemoglobin alpha binding+++GO:0031722///hemoglobin beta binding+++GO:0043177///organic acid binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006749///glutathione metabolic process+++GO:0010999///regulation of eIF2 alpha phosphorylation by heme+++GO:0015671///oxygen transport+++GO:0030097///hemopoiesis+++GO:0042744///hydrogen peroxide catabolic process+++GO:0048821///erythrocyte development+++GO:0098869///cellular oxidant detoxification 101488212 101488212 'Evi2' mRNA 45.36 0 40.88 0.62 0 0.59 1.45 3.04 2.72 0.403333333 2.403333333 122.65 251.17 222.84 28.74666667 198.8866667 0.101661935 2.779863442 GO:0016021///integral component of membrane GO:0030854///positive regulation of granulocyte differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045660///positive regulation of neutrophil differentiation+++GO:0061515///myeloid cell development+++GO:0071157///negative regulation of cell cycle arrest+++GO:2000035///regulation of stem cell division 101489 101489 'Ric8a' mRNA 1583 1715 1617 29.33 31.27 31.78 28.47 25.36 28.39 30.79333333 27.40666667 1768 1538 1707 1638.333333 1671 0.880306125 0.015637736 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0001965///G-protein alpha-subunit binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0001944///vasculature development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007369///gastrulation+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008542///visual learning+++GO:0009416///response to light stimulus+++GO:0042074///cell migration involved in gastrulation+++GO:0050790///regulation of catalytic activity+++GO:0070586///cell-cell adhesion involved in gastrulation+++GO:0071711///basement membrane organization 101490 101490 'Inpp5f' mRNA 980 1055 856 15.4 13.98 12.82 10.04 9.75 10.22 14.06666667 10.00333333 785 763 717 963.6666667 755 2.52E-04 -0.360805756 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0008934///inositol monophosphate 1-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0034595///phosphatidylinositol phosphate 5-phosphatase activity+++GO:0034596///phosphatidylinositol phosphate 4-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity+++GO:0052832///inositol monophosphate 3-phosphatase activity+++GO:0052833///inositol monophosphate 4-phosphatase activity+++GO:0052834///inositol monophosphate phosphatase activity GO:0001921///positive regulation of receptor recycling+++GO:0008344///adult locomotory behavior+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0031161///phosphatidylinositol catabolic process+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048681///negative regulation of axon regeneration+++GO:0051896///regulation of protein kinase B signaling+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0072583///clathrin-dependent endocytosis+++GO:2000145///regulation of cell motility+++GO:2001135///regulation of endocytic recycling 101497 101497 'Plekhg2' mRNA 797 756 651 8.98 8.19 7.79 8.73 9.02 8.85 8.32 8.866666667 908 914 885 734.6666667 902.3333333 0.00455447 0.287805091 GO:0005085///guanyl-nucleotide exchange factor activity GO:0030833///regulation of actin filament polymerization+++GO:0050790///regulation of catalytic activity 101502 101502 'Hsd3b7' mRNA 809 753 828 25.52 23.41 27.79 48.32 45.18 43.45 25.57333333 45.65 1754 1603 1528 796.6666667 1628.333333 2.61E-28 1.016549957 00120///Primary bile acid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0047016///cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity" GO:0001558///regulation of cell growth+++GO:0006694///steroid biosynthetic process+++GO:0006707///cholesterol catabolic process+++GO:0035754///B cell chemotaxis 101513 101513 'Mob2' mRNA 906 1112 1001 36.73 44.25 43.07 36.63 32.19 34.7 41.35 34.50666667 1041 895 951 1006.333333 962.3333333 0.546352264 -0.077455879 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0044306///neuron projection terminus+++GO:0048471///perinuclear region of cytoplasm GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0030036///actin cytoskeleton organization 101533 101533 'Klk9' mRNA 2 2 0 0.1 0.1 0 0.09 0 0.09 0.066666667 0.06 2 0 2 1.333333333 1.333333333 0.998591786 0.008691646 GO:0030141///secretory granule GO:0003674///molecular_function+++GO:0004252///serine-type endopeptidase activity GO:0008150///biological_process 101540 101540 'Prkd2' mRNA 777 794 764 12.22 12.04 12.6 7.89 7.95 7.96 12.28666667 7.933333333 588 568 573 778.3333333 576.3333333 1.24E-05 -0.445436527 04015///Rap1 signaling pathway+++04925///Aldosterone synthesis and secretion+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005080///protein kinase C binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0008219///cell death+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045785///positive regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0050852///T cell receptor signaling pathway+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0089700///protein kinase D signaling+++GO:1901727///positive regulation of histone deacetylase activity+++GO:1902533///positive regulation of intracellular signal transduction+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2001028///positive regulation of endothelial cell chemotaxis 101543 101543 'Wtip' mRNA 129 100 97 3.76 2.87 3 3.14 3.04 2.75 3.21 2.976666667 124 117 105 108.6666667 115.3333333 0.82482207 0.075524427 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis+++GO:0030030///cell projection organization+++GO:0031047///gene silencing by RNA+++GO:0035195///gene silencing by miRNA+++GO:0035331///negative regulation of hippo signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2000637///positive regulation of gene silencing by miRNA" 101544 101544 'Zfp575' mRNA 84.48 83.05 64.24 1.76 1.68 1.41 1.04 0.78 0.73 1.616666667 0.85 59.42 41.29 38.19 77.25666667 46.3 0.027783928 -0.753382006 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 101565 101565 'Ccp110' mRNA 570 500 482 6.04 5.22 5.46 2.23 2.21 2.59 5.573333333 2.343333333 241 232 270 517.3333333 247.6666667 3.62E-15 -1.073221654 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0005515///protein binding GO:0007099///centriole replication+++GO:0030030///cell projection organization+++GO:0032053///ciliary basal body organization+++GO:0032465///regulation of cytokinesis+++GO:0045724///positive regulation of cilium assembly+++GO:0051298///centrosome duplication+++GO:1902018///negative regulation of cilium assembly+++GO:1903723///negative regulation of centriole elongation 101568 101568 'Vrk3' mRNA 1259 1491 1386 40.92 48.07 47.96 37.27 35.79 39.11 45.65 37.39 1317 1228 1342 1378.666667 1295.666667 0.338033825 -0.102166819 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0019903///protein phosphatase binding GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 101592 101592 'Efl1' mRNA 569 629 536 8.55 9.29 8.52 7.13 7.1 8.14 8.786666667 7.456666667 546 532 603 578 560.3333333 0.729102832 -0.054395702 03008///Ribosome biogenesis in eukaryotes GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0043022///ribosome binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0046039///GTP metabolic process 101602 101602 'AI467606' mRNA 111 98 92 3.16 2.82 2.82 10.85 13.05 10.83 2.933333333 11.57666667 426 507 416 100.3333333 449.6666667 7.02E-37 2.155326091 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 101604 101604 'E430018J23Rik' mRNA 170.06 147 166 4.24 3.46 4.39 3.05 3.3 4.02 4.03 3.456666667 150 154 181 161.02 161.6666667 0.985634415 -0.007114175 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 101612 101612 'Grwd1' mRNA 611 648 582 18.02 19 18.28 15.82 15.96 16.39 18.43333333 16.05666667 615 604 621 613.6666667 613.3333333 0.936922999 -0.011346901 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0042393///histone binding GO:0006260///DNA replication+++GO:0006334///nucleosome assembly+++GO:0006337///nucleosome disassembly 101613 101613 'Nlrp6' mRNA 48 46 20 0.59 0.55 0.26 0.07 0.21 0.04 0.466666667 0.106666667 7 19 4 38 10 0.002856625 -1.915050252 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0061702///inflammasome complex GO:0000166///nucleotide binding+++GO:0005000///vasopressin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042277///peptide binding GO:0002376///immune system process+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0002526///acute inflammatory response+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0006954///inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0010506///regulation of autophagy+++GO:0032611///interleukin-1 beta production+++GO:0032621///interleukin-18 production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0042060///wound healing+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043409///negative regulation of MAPK cascade+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0050777///negative regulation of immune response+++GO:0070255///regulation of mucus secretion+++GO:0070266///necroptotic process+++GO:0070269///pyroptosis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070946///neutrophil mediated killing of gram-positive bacterium+++GO:0097202///activation of cysteine-type endopeptidase activity 101631 101631 'Pwwp2b' mRNA 290 287 251 6.78 6.68 6.26 8.63 9.51 6.94 6.573333333 8.36 423 457 330 276 403.3333333 8.41E-04 0.538072367 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 101685 101685 'Spty2d1' mRNA 751 704 776 7.66 7.06 8.4 9.36 8.42 9.25 7.706666667 9.01 1056 928 1011 743.6666667 998.3333333 8.17E-05 0.409855123 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0001042///RNA polymerase I core binding+++GO:0003677///DNA binding+++GO:0042393///histone binding "GO:0006334///nucleosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010847///regulation of chromatin assembly+++GO:0043486///histone exchange" 101700 101700 'Trim68' mRNA 204 211 210 4.79 4.87 5.22 3.61 2.96 3.24 4.96 3.27 177 142 154 208.3333333 157.6666667 0.034920965 -0.416189268 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0035035///histone acetyltransferase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0060765///regulation of androgen receptor signaling pathway 101706 101706 'Numa1' mRNA 3347 3498 3254 24.2 24.83 24.98 17.34 17.53 17.05 24.67 17.30666667 2768 2735 2632 3366.333333 2711.666667 2.18E-07 -0.323328531 GO:0000139///Golgi membrane+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0016363///nuclear matrix+++GO:0019897///extrinsic component of plasma membrane+++GO:0030425///dendrite+++GO:0031616///spindle pole centrosome+++GO:0032991///protein-containing complex+++GO:0035371///microtubule plus-end+++GO:0036449///microtubule minus-end+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell+++GO:0055028///cortical microtubule+++GO:0061673///mitotic spindle astral microtubule+++GO:0072686///mitotic spindle+++GO:0097427///microtubule bundle+++GO:0097431///mitotic spindle pole+++GO:0097575///lateral cell cortex+++GO:0099738///cell cortex region+++GO:1905720///cytoplasmic microtubule bundle+++GO:1990023///mitotic spindle midzone GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0015631///tubulin binding+++GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding+++GO:0044877///protein-containing complex binding+++GO:0051010///microtubule plus-end binding+++GO:0051011///microtubule minus-end binding+++GO:0070840///dynein complex binding+++GO:0097718///disordered domain specific binding GO:0000132///establishment of mitotic spindle orientation+++GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030953///astral microtubule organization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0032388///positive regulation of intracellular transport+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051798///positive regulation of hair follicle development+++GO:0051984///positive regulation of chromosome segregation+++GO:0055048///anastral spindle assembly+++GO:0060236///regulation of mitotic spindle organization+++GO:0060487///lung epithelial cell differentiation+++GO:0090235///regulation of metaphase plate congression+++GO:1902365///positive regulation of protein localization to spindle pole body+++GO:1902846///positive regulation of mitotic spindle elongation+++GO:1904778///positive regulation of protein localization to cell cortex+++GO:1905820///positive regulation of chromosome separation+++GO:1905832///positive regulation of spindle assembly 101739 101739 'Psip1' mRNA 936.28 905.07 642.53 18.1 16.41 12.17 11.45 11.15 13.02 15.56 11.87333333 684.55 633.14 749.63 827.96 689.1066667 0.04409437 -0.270090206 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0034399///nuclear periphery+++GO:0035327///transcriptionally active chromatin GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0033613///activating transcription factor binding+++GO:0097100///supercoiled DNA binding GO:0000395///mRNA 5'-splice site recognition+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006979///response to oxidative stress+++GO:0009408///response to heat+++GO:0045944///positive regulation of transcription by RNA polymerase II 101744 101744 'Acp7' mRNA 2190 1998 2055 31.67 28.45 29.28 13 13.33 12.81 29.8 13.04666667 1010 916 935 2081 953.6666667 1.28E-45 -1.138928482 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003993///acid phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0016311///dephosphorylation 101772 101772 'Ano1' mRNA 107 123 119 1.25 1.4 1.49 1.61 1.41 1.42 1.38 1.48 159 137 136 116.3333333 144 0.233675675 0.293967551 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0034707///chloride channel complex+++GO:0045121///membrane raft GO:0005102///signaling receptor binding+++GO:0005227///calcium activated cation channel activity+++GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0015111///iodide transmembrane transporter activity+++GO:0017128///phospholipid scramblase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006821///chloride transport+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0015705///iodide transport+++GO:0034605///cellular response to heat+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042391///regulation of membrane potential+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0055085///transmembrane transport+++GO:0060438///trachea development+++GO:0098655///cation transmembrane transport+++GO:1901653///cellular response to peptide+++GO:1902476///chloride transmembrane transport 101809 101809 'Spred3' mRNA 168 195 178 2.44 2.99 2.67 2.73 2.83 3.27 2.7 2.943333333 210 204 239 180.3333333 217.6666667 0.199998666 0.260134958 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005173///stem cell factor receptor binding+++GO:0019901///protein kinase binding "GO:0000188///inactivation of MAPK activity+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0043409///negative regulation of MAPK cascade+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090311///regulation of protein deacetylation+++GO:1902747///negative regulation of lens fiber cell differentiation" 101831 101831 'Faap24' mRNA 171 234 171 5.52 7.44 5.85 8.32 9.22 7.83 6.27 8.456666667 296.46 320.5 270 192 295.6533333 7.01E-04 0.613747993 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043240///Fanconi anaemia nuclear complex GO:0003677///DNA binding+++GO:0003682///chromatin binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008150///biological_process+++GO:0036297///interstrand cross-link repair 101835 101835 'AW146154' mRNA 295.64 279.69 287.3 4.72 4.39 4.87 2.61 2.41 2.42 4.66 2.48 188.22 169.58 169.03 287.5433333 175.61 1.32E-05 -0.724319583 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 101861 101861 'Ints4' mRNA 1462 1490 1472 24.66 24.73 26.32 21.58 22.25 20.19 25.23666667 21.34 1473 1484 1334 1474.666667 1430.333333 0.597219883 -0.056472048 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing 101867 101867 'Rrp8' mRNA 543.46 500.02 496.09 10.48 9.5 10.14 11.5 9.81 9.26 10.04 10.19 686.07 572.15 535.08 513.19 597.7666667 0.126040545 0.206974211 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0033553///rDNA heterochromatin GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0035064///methylated histone binding GO:0000183///chromatin silencing at rDNA+++GO:0006325///chromatin organization+++GO:0006364///rRNA processing+++GO:0032259///methylation+++GO:0042149///cellular response to glucose starvation+++GO:0046015///regulation of transcription by glucose+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 101869 101869 'Unc45a' mRNA 1475 1497 1457 24.11 24.24 25.29 18.68 17.29 17.39 24.54666667 17.78666667 1312 1193 1184 1476.333333 1229.666667 8.33E-04 -0.27657166 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0051879///Hsp90 protein binding GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0030154///cell differentiation+++GO:0061077///chaperone-mediated protein folding 101883 101883 'Igflr1' mRNA 287 276 301 14.9 14.15 16.58 8.68 7.05 7.91 15.21 7.88 192 152 169 288 171 1.01E-05 -0.767808088 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process 101943 101943 'Sf3b3' mRNA 2476 2490.94 2471.24 30.95 30.63 32.74 27.87 25.9 23.96 31.44 25.91 2566.92 2330 2136.85 2479.393333 2344.59 0.295545662 -0.094365382 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0030620///U2 snRNA binding+++GO:0044877///protein-containing complex binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0042177///negative regulation of protein catabolic process" 101966 101966 'D8Ertd738e' mRNA 1868.26 1742.39 1900.1 206.18 191.41 222.12 219.93 257.69 210.97 206.57 229.53 2277.5 2592.79 2102.33 1836.916667 2324.206667 9.19E-04 0.326244239 GO:0003674///molecular_function GO:0008150///biological_process 101985 101985 'Usb1' mRNA 543.38 539.76 512.36 17.54 16.97 17.49 28.3 30.29 28.1 17.33333333 28.89666667 1001.12 1045.35 963 531.8333333 1003.156667 1.64E-20 0.90581879 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0045171///intercellular bridge "GO:0000175///3'-5'-exoribonuclease activity+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:1990838///poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends" "GO:0008380///RNA splicing+++GO:0034472///snRNA 3'-end processing+++GO:0034477///U6 snRNA 3'-end processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 101994 101994 'Champ1' mRNA 767 882 834 10.32 11.66 11.89 8.66 7.95 8.61 11.29 8.406666667 741 665 714 827.6666667 706.6666667 0.029049891 -0.241088893 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0090543///Flemming body" GO:0046872///metal ion binding GO:0031134///sister chromatid biorientation+++GO:0034501///protein localization to kinetochore+++GO:0035372///protein localization to microtubule+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore 102022 102022 'Ces2a' mRNA 2.1 1.01 5.69 0.06 0.03 0.19 0 0.03 0 0.093333333 0.01 0 1 0 2.933333333 0.333333333 0.241979686 -2.939503045 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102209///trans-permethrin hydrolase activity" GO:0006486///protein glycosylation+++GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process+++GO:0042572///retinol metabolic process 102032 102032 'Smim19' mRNA 728.78 700 569 31.1 29.47 25.76 17.16 18.55 18.42 28.77666667 18.04333333 461.74 487 480 665.9266667 476.2466667 3.34E-05 -0.490971739 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102058 102058 'Exoc8' mRNA 397 404 431 2.83 2.83 3.25 2.87 2.64 2.99 2.97 2.833333333 465 418 469 410.6666667 450.6666667 0.448448242 0.119561657 GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0031267///small GTPase binding+++GO:0035091///phosphatidylinositol binding GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0007032///endosome organization+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0022617///extracellular matrix disassembly+++GO:0034613///cellular protein localization 102060 102060 'Gadd45gip1' mRNA 761.07 775.63 684.86 25.42 25.53 24.26 22.47 22.73 21.75 25.07 22.31666667 773.23 763.38 724.34 740.52 753.65 0.901881082 0.015741658 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005840///ribosome GO:0005515///protein binding+++GO:0097177///mitochondrial ribosome binding GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0071850///mitotic cell cycle arrest+++GO:1903862///positive regulation of oxidative phosphorylation 102075 102075 'Plekhg4' mRNA 8 6 8 0.1 0.07 0.11 0.44 0.43 0.51 0.093333333 0.46 42 39 47 7.333333333 42.66666667 3.55E-06 2.526666749 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 102093 102093 'Phkb' mRNA 1336 1416 1247 14.93 15.63 14.75 10.87 11.43 10.64 15.10333333 10.98 1102 1148 1051 1333 1100.333333 9.20E-04 -0.28652816 04020///Calcium signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005886///plasma membrane+++GO:0005964///phosphorylase kinase complex+++GO:0016020///membrane GO:0005516///calmodulin binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006468///protein phosphorylation 102098 102098 'Arhgef18' mRNA 751 742 803 7.54 7.34 8.55 7.52 6.49 7.9 7.81 7.303333333 863 731 879 765.3333333 824.3333333 0.500945183 0.091864256 04530///Tight junction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0045177///apical part of cell GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051497///negative regulation of stress fiber assembly 102103 102103 'Mtus1' mRNA 3715 3964 3673 34.19 35.97 35.43 27.33 26.65 27.98 35.19666667 27.32 2985 2834 2922 3784 2913.666667 1.31E-10 -0.388737416 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0010758///regulation of macrophage chemotaxis 102115 102115 'Dohh' mRNA 1195 1219 1163 49.43 49.74 51.04 52.47 51.6 53.76 50.07 52.61 1457 1398 1444 1192.333333 1433 0.001731177 0.253497282 GO:0005575///cellular_component+++GO:0016021///integral component of membrane GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0019135///deoxyhypusine monooxygenase activity+++GO:0046872///metal ion binding GO:0008612///peptidyl-lysine modification to peptidyl-hypusine 102122 102122 'Psme3ip1' mRNA 927 971.77 921 29.35 30.38 31.68 29.05 30.51 27.83 30.47 29.13 1034 1070.96 972.81 939.9233333 1025.923333 0.279194597 0.114480507 GO:0005634///nucleus GO:0003674///molecular_function GO:0032091///negative regulation of protein binding+++GO:1901799///negative regulation of proteasomal protein catabolic process 102124 102124 'Enkd1' mRNA 261 278 248 11.96 12.56 12.06 6.9 7.61 6.8 12.19333333 7.103333333 173 186 166 262.3333333 175 5.64E-04 -0.594023062 GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0097546///ciliary base GO:0003674///molecular_function GO:0008150///biological_process 102141 102141 'Snx25' mRNA 294 318 324 4.89 5.21 5.74 3.28 3.44 3.31 5.28 3.343333333 226 232 221 312 226.3333333 0.003182658 -0.476306841 GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0034713///type I transforming growth factor beta receptor binding+++GO:0035091///phosphatidylinositol binding GO:0015031///protein transport+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032801///receptor catabolic process+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation 102162 102162 'Taf5l' mRNA 499 565 185 9.2 10.26 3.62 4.01 4.73 5.13 7.693333333 4.623333333 250 288 310 416.3333333 282.6666667 0.312316141 -0.546465642 03022///Basal transcription factors GO:0000123///histone acetyltransferase complex+++GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0016607///nuclear speck+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003713///transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904672///regulation of somatic stem cell population maintenance" 102182 102182 'Prmt9' mRNA 300 288 142 6.05 6.04 3.41 3.4 3.63 3.3 5.166666667 3.443333333 170 192 162 243.3333333 174.6666667 0.060023494 -0.474993773 GO:0005737///cytoplasm GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0035241///protein-arginine omega-N monomethyltransferase activity+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity "GO:0006397///mRNA processing+++GO:0018216///peptidyl-arginine methylation+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0032259///methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0035247///peptidyl-arginine omega-N-methylation" 102193 102193 'Zdhhc7' mRNA 1076 1158 907 20.95 22.01 18.58 18.69 21.29 20.75 20.51333333 20.24333333 1101 1229 1190 1047 1173.333333 0.142412929 0.15784496 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009895///negative regulation of catabolic process+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0030859///polarized epithelial cell differentiation+++GO:0044381///glucose import in response to insulin stimulus+++GO:1902044///regulation of Fas signaling pathway+++GO:1903076///regulation of protein localization to plasma membrane 102209 102209 'Snapc2' mRNA 963 1027 954 37.52 39.42 39.41 34.51 32.33 34.7 38.78333333 33.84666667 1019 932 992 981.3333333 981 0.916747509 -0.012393961 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0008150///biological_process 102216272 102216272 'Ak6' mRNA 287.67 277.03 311.52 18.62 17.74 21.4 35.2 33.97 30.59 19.25333333 33.25333333 623.25 586.31 523.51 292.0733333 577.69 4.29E-13 0.970007519 00230///Purine metabolism+++01240///Biosynthesis of cofactors+++03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004140///dephospho-CoA kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016887///ATPase activity GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation+++GO:0046940///nucleoside monophosphate phosphorylation 102247 102247 'Gpat4' mRNA 1663 1705 1587 22.36 22.49 22.67 25.62 25.17 25.11 22.50666667 25.3 2171 2093 2072 1651.666667 2112 7.20E-07 0.34336621 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0004366///glycerol-3-phosphate O-acyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0102420///sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity" GO:0002071///glandular epithelial cell maturation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0007595///lactation+++GO:0008610///lipid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0030879///mammary gland development+++GO:0040014///regulation of multicellular organism growth+++GO:0046339///diacylglycerol metabolic process 102278 102278 'Cpne7' mRNA 28 32 36 0.73 0.78 0.99 5.85 5.45 5.67 0.833333333 5.656666667 271 247 240 32 252.6666667 2.92E-35 2.966789829 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0071277///cellular response to calcium ion 102294 102294 'Cyp4v3' mRNA 456 455 488 8.66 8.51 9.84 11.33 11.18 10.78 9.003333333 11.09666667 686 661 632 466.3333333 659.6666667 3.44E-05 0.486247759 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0102033///fatty acid omega-hydroxylase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0010430///fatty acid omega-oxidation 102323 102323 'Dcun1d2' mRNA 611.19 572.68 650.28 11.92 10.88 13.42 11.29 10.22 11.35 12.07333333 10.95333333 673.55 589.7 653.58 611.3833333 638.9433333 0.768822842 0.04742292 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032182///ubiquitin-like protein binding+++GO:0097602///cullin family protein binding GO:0045116///protein neddylation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000434///regulation of protein neddylation+++GO:2000436///positive regulation of protein neddylation 102334 102334 'Ankrd10' mRNA 1795.42 1767.99 1731.64 31.02 30.62 31.75 28.52 26.76 25.27 31.13 26.85 1785.7 1665.4 1600.1 1765.016667 1683.733333 0.367659446 -0.080368418 GO:0005575///cellular_component GO:0003674///molecular_function 102339 102339 'Cog4' mRNA 913 1116.06 902.76 18.28 22.03 19.19 21.77 23.46 23.87 19.83333333 23.03333333 1249.08 1315 1327.15 977.2733333 1297.076667 3.88E-05 0.400168237 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0042802///identical protein binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0048213///Golgi vesicle prefusion complex stabilization" 102371 102371 'Myzap' mRNA 659 723 684 16.21 17.52 17.85 19.23 18.23 21.04 17.19333333 19.5 899 832 952 688.6666667 894.3333333 4.61E-04 0.364782165 "GO:0005622///intracellular+++GO:0005635///nuclear envelope+++GO:0005665///RNA polymerase II, core complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031674///I band" GO:0005515///protein binding GO:0035556///intracellular signal transduction 102414 102414 'Clk3' mRNA 1951.14 2020.55 1711.29 53.83 54.84 50.37 42.47 44.44 43.12 53.01333333 43.34333333 1681.8 1721.38 1665.87 1894.326667 1689.683333 0.026666012 -0.174039961 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045111///intermediate filament cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation 102423 102423 'Hinfp' mRNA 452.5 465 464.04 3.88 4.46 4.78 5.07 4.28 4.93 4.373333333 4.76 475 417.81 416 460.5133333 436.27 0.557553807 -0.091999332 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0015030///Cajal body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding" "GO:0000077///DNA damage checkpoint+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006281///DNA repair+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0045184///establishment of protein localization+++GO:0045445///myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development" 102436 102436 'Lars2' mRNA 314 378 392 4.34 5.12 5.72 4.29 3.94 3.66 5.06 3.963333333 357 322 295 361.3333333 324.6666667 0.348692266 -0.170218608 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004823///leucine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006429///leucyl-tRNA aminoacylation+++GO:0032543///mitochondrial translation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 102442 102442 'Dennd4a' mRNA 846 763.26 648 5.22 4.66 4.25 3.31 2.79 3.22 4.71 3.106666667 616 511 578.92 752.42 568.64 4.65E-04 -0.41405453 GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity GO:0032483///regulation of Rab protein signal transduction+++GO:0050790///regulation of catalytic activity 102443350 102443350 'Xndc1' mRNA 248.43 214.02 170.5 4.19 3.56 3.07 3.38 3.17 3.64 3.606666667 3.396666667 229 210.16 241.04 210.9833333 226.7333333 0.681962142 0.098551061 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0034703///cation channel complex "GO:0003674///molecular_function+++GO:0003684///damaged DNA binding+++GO:0015279///store-operated calcium channel activity+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0000012///single strand break repair+++GO:0006828///manganese ion transport+++GO:0007338///single fertilization+++GO:0008150///biological_process+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0070588///calcium ion transmembrane transport 102443351 102443351 'Xntrpc' mRNA 68.57 69.98 67.5 0.82 0.82 0.85 0 0.29 0.08 0.83 0.123333333 0 27.84 7.24 68.68333333 11.69333333 0.090488898 -2.575749312 GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034703///cation channel complex "GO:0003684///damaged DNA binding+++GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0015279///store-operated calcium channel activity+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0000012///single strand break repair+++GO:0006811///ion transport+++GO:0006828///manganese ion transport+++GO:0007338///single fertilization+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport 102448 102448 'Xylb' mRNA 137 156 164 1.93 2.16 2.7 1.55 1.95 1.59 2.263333333 1.696666667 110 143 110 152.3333333 121 0.173391472 -0.344831088 00040///Pentose and glucuronate interconversions GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0004856///xylulokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0005997///xylulose metabolic process+++GO:0016310///phosphorylation+++GO:0042732///D-xylose metabolic process+++GO:0046835///carbohydrate phosphorylation 102462 102462 'Imp3' mRNA 881 849 751 64.43 61.47 58.28 65.05 59.3 64.3 61.39333333 62.88333333 1019 905 973 827 965.6666667 0.031498177 0.213257359 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030684///preribosome+++GO:0032040///small-subunit processome+++GO:0034457///Mpp10 complex GO:0003723///RNA binding+++GO:0019843///rRNA binding+++GO:0030515///snoRNA binding GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 102502 102502 'Pls1' mRNA 8703 8827 8501 126.22 126.49 131.39 33.95 33.58 32.94 128.0333333 33.49 2685 2591 2524 8677 2600 1.67E-223 -1.750883265 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005903///brush border+++GO:0032420///stereocilium+++GO:0032432///actin filament bundle+++GO:0042995///cell projection+++GO:1990357///terminal web GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0001951///intestinal D-glucose absorption+++GO:0030033///microvillus assembly+++GO:0032532///regulation of microvillus length+++GO:0040018///positive regulation of multicellular organism growth+++GO:0051017///actin filament bundle assembly+++GO:0051639///actin filament network formation+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060121///vestibular receptor cell stereocilium organization+++GO:1902896///terminal web assembly+++GO:1903078///positive regulation of protein localization to plasma membrane 102545 102545 'Cmtm7' mRNA 981 1038 978 54 56.39 57.03 77.41 90.19 84.58 55.80666667 84.06 1618 1837 1710 999 1721.666667 7.16E-19 0.774939171 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005125///cytokine activity GO:0002337///B-1a B cell differentiation+++GO:0006935///chemotaxis+++GO:0007165///signal transduction 102566 102566 'Ano10' mRNA 1494 1615 1556 31.19 33.27 34.52 31.22 29.34 29.99 32.99333333 30.18333333 1719 1575 1599 1555 1631 0.577538 0.055839723 GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005227///calcium activated cation channel activity+++GO:0005229///intracellular calcium activated chloride channel activity+++GO:0017128///phospholipid scramblase activity GO:0006812///cation transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 102570 102570 'Slc22a13' mRNA 11 2 13 0.3 0.06 0.34 0.08 0.13 0.09 0.233333333 0.1 5 5 4 8.666666667 4.666666667 0.442652519 -0.925313245 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0022857///transmembrane transporter activity+++GO:0090416///nicotinate transmembrane transporter activity GO:0002854///positive regulation of T cell mediated cytotoxicity directed against tumor cell target+++GO:0015747///urate transport+++GO:0045922///negative regulation of fatty acid metabolic process+++GO:0055085///transmembrane transport+++GO:2001142///nicotinate transport 102580 102580 'Alg9' mRNA 357 335 156 7.36 6.68 3.58 4.12 4.16 4.04 5.873333333 4.106666667 227 222 213 282.6666667 220.6666667 0.169308933 -0.353775662 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000026///alpha-1,2-mannosyltransferase activity+++GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0052918///dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity+++GO:0052926///dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0097502///mannosylation 102595 102595 'Plekho2' mRNA 879 912 924 13.88 14.27 15.51 29.96 31.65 30.04 14.55333333 30.55 2190 2236 2123 905 2183 1.24E-55 1.257664439 GO:0005575///cellular_component GO:0003674///molecular_function GO:0071888///macrophage apoptotic process 102607 102607 'Snx19' mRNA 1158 1245 1347 11.01 11.62 13.65 9.06 9.02 8.18 12.09333333 8.753333333 1089 1053 947 1250 1029.666667 0.006100195 -0.295390299 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding GO:0002062///chondrocyte differentiation+++GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0030073///insulin secretion+++GO:1990502///dense core granule maturation 102614 102614 'Rpp25' mRNA 5 7 6 0.22 0.31 0.28 0.78 0.84 0.48 0.27 0.7 20 21 12 6 17.66666667 0.048131083 1.546390201 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030677///ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex+++GO:0034451///centriolar satellite GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 102626 102626 'Mapkapk3' mRNA 448 498 428 8.94 9.7 8.91 18.65 19.25 19.97 9.183333333 19.29 1087 1089 1121 458 1099 2.73E-38 1.252945506 04010///MAPK signaling pathway+++04370///VEGF signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0002224///toll-like receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0034097///response to cytokine+++GO:0035556///intracellular signal transduction+++GO:0044351///macropinocytosis+++GO:0046777///protein autophosphorylation 102631503 102631503 'Gm29825' mRNA 1 2 0 0.03 0.06 0 0.04 0.06 0.08 0.03 0.06 1.5 2.37 3 1 2.29 0.703304273 1.022268853 102631681 102631681 'Gm29958' mRNA 1 3 0 0.05 0.15 0 0 0 0 0.066666667 0 0 0 0 1.333333333 0 0.492448657 -2.82872934 102631705 102631705 'Gm29975' mRNA 876.53 983 897.01 1.84 2.02 2 1.86 1.82 1.94 1.953333333 1.873333333 1023 979 1031 918.8466667 1011 0.222009398 0.126671758 102631730 102631730 '4930512M02Rik' mRNA 167.25 142.47 139 16.14 13.65 14.24 8.62 6.64 7.85 14.67666667 7.703333333 102.18 76.57 89.73 149.5733333 89.49333333 0.001418072 -0.759329913 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102631805 102631805 'Gm272' mRNA 0 2 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 102631912 102631912 'Ndufb1' mRNA 446 414 613 158.86 149.96 232.8 170.26 194.74 199.1 180.54 188.0333333 535 592 600 491 575.6666667 0.265103892 0.208921923 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0070469///respiratory chain GO:0003954///NADH dehydrogenase activity GO:0032981///mitochondrial respiratory chain complex I assembly 102631952 102631952 'Gm5928' mRNA 2 1 2 0.13 0.06 0.13 0.06 0.11 0.23 0.106666667 0.133333333 1 2 4 1.666666667 2.333333333 0.847264218 0.471682808 102632 102632 'Acad11' mRNA 1021 1048 1036 16.69 16.85 17.96 11.05 11.23 11.97 17.16666667 11.41666667 778 772 816 1035 788.6666667 1.84E-05 -0.404435436 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane "GO:0004466///long-chain-acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0070991///medium-chain-acyl-CoA dehydrogenase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase 102632113 102632113 'Gm3727' mRNA 1 0 0 0.11 0 0 0 0 0.2 0.036666667 0.066666667 0 0 2 0.333333333 0.666666667 0.863090843 0.890645578 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102632142 102632142 'Gm18905' mRNA 3 0 2 0.07 0 0.05 0 0.02 0 0.04 0.006666667 0 1 0 1.666666667 0.333333333 0.494453423 -2.242820423 102632224 102632224 'Gm8062' mRNA 10 9.26 8.23 1.37 1.27 1.2 0.33 0.21 1 1.28 0.513333333 2.74 1.68 7.98 9.163333333 4.133333333 0.221872431 -1.441277408 102632353 102632353 'Gm30447' mRNA 15 6.64 5 0.12 0.05 0.04 0.06 0.04 0.01 0.07 0.036666667 8 6 2 8.88 5.333333333 0.56394486 -0.706365209 102632403 102632403 'Rpl17-ps8' mRNA 33.2 34.01 26.77 2.3 2.34 1.97 2.16 2.06 2.68 2.203333333 2.3 35.73 33.16 42.75 31.32666667 37.21333333 0.666836161 0.234868469 102632425 102632425 'Gm30500' mRNA 2595 2596 2354 80.82 79.68 77.78 7.26 6.38 6.66 79.42666667 6.766666667 268 230 238 2515 245.3333333 0 -3.36886732 102632427 102632427 'Gm30502' mRNA 5.08 6.1 4.06 0.17 0.2 0.15 0 0.06 0.06 0.173333333 0.04 0 2.01 2.02 5.08 1.343333333 0.250717656 -1.902591946 102632470 102632470 'Gm30534' mRNA 0 1 0 0 0.42 0 0 0 0 0.14 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05110///Vibrio cholerae infection 102632483 102632483 'Gm17330' mRNA 65.92 57.5 23.85 1.27 1.77 0.85 0.36 0.31 0.57 1.296666667 0.413333333 30.02 19.54 27.91 49.09 25.82333333 0.061733371 -0.929897195 102632554 102632554 'Gm30599' mRNA 0 2 2 0 0.09 0.1 0.04 0.08 0 0.063333333 0.04 1 2 0 1.333333333 1 0.884675627 -0.434297309 102632660 102632660 'Gm30679' mRNA 3 3 8 0.06 0.05 0.16 0.05 0.1 0.05 0.09 0.066666667 3 6 3 4.666666667 4 0.866193436 -0.251582739 102632693 102632693 'Gm30698' mRNA 3.12 1.05 1.06 0.16 0.05 0.06 0.04 0.05 0 0.09 0.03 1 1 0 1.743333333 0.666666667 0.651934667 -1.327111254 102632737 102632737 'Gm30732' mRNA 25 15 17 0.32 0.19 0.23 0.22 0.11 0.15 0.246666667 0.16 20 10 13 19 14.33333333 0.585292461 -0.422464833 102632738 102632738 'Gm30733' mRNA 4 1 1 0.06 0.01 0.02 0.03 0.03 0.05 0.03 0.036666667 2 2 4 2 2.666666667 0.860896788 0.414786444 102632739 102632739 'Gm19774' mRNA 0 0 1.74 0 0 0.38 0.43 0 0.27 0.126666667 0.233333333 2.33 0 1.39 0.58 1.24 0.73494348 1.452265523 102632837 102632837 'Rnf212b' mRNA 0 0 1 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000795///synaptonemal complex GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0016925///protein sumoylation 102633050 102633050 'Gm6293' mRNA 13 9 8 2.7 1.88 1.77 1.1 1.14 1.53 2.116666667 1.256666667 6 6 8 10 6.666666667 0.571394081 -0.591592201 102633075 102633075 'Gm30990' mRNA 18.68 13 11 0.14 0.1 0.09 0.06 0.03 0.03 0.11 0.04 9 4 5 14.22666667 6 0.157874058 -1.234597485 102633156 102633156 'Gm4631' mRNA 16.7 19.44 37.86 0.1 0.11 0.22 0.22 0.18 0.03 0.143333333 0.143333333 47.85 34.99 6.49 24.66666667 29.77666667 0.791143807 0.235745409 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 102633230 102633230 'Gm11633' mRNA 1 2 0 0.02 0.03 0 0.06 0.13 0.03 0.016666667 0.073333333 4 9 2 1 5 0.188391016 2.339530253 102633301 102633301 'Gm31160' mRNA 4 5 1 0.03 0.04 0.01 0.04 0.02 0.01 0.026666667 0.023333333 2 3 1 3.333333333 2 0.720293678 -0.724043171 GO:0016020///membrane+++GO:0016021///integral component of membrane 102633424 102633424 'Gm31255' mRNA 57.75 45.31 71.01 0.16 0.12 0.21 0.17 0.1 0.12 0.163333333 0.13 68.89 42.08 46.54 58.02333333 52.50333333 0.723917416 -0.173894323 102633458 102633458 'Gm11100' mRNA 8.17 15.43 16.37 0.29 0.54 0.61 0.67 0.36 0.46 0.48 0.496666667 21.91 11.44 14.39 13.32333333 15.91333333 0.819571138 0.2151231 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102633498 102633498 'Gm31309' mRNA 12 4 2 0.4 0.13 0.07 0.12 0 0.09 0.2 0.07 4 0 3 6 2.333333333 0.389904241 -1.367152488 102633525 102633525 'Gm31332' mRNA 12.02 14.03 10.02 0.27 0.31 0.24 0.39 0.22 0.4 0.273333333 0.336666667 20.03 11.01 20.03 12.02333333 17.02333333 0.537294085 0.491950371 102633750 102633750 'Gm10130' mRNA 112.36 97.8 73.78 2.99 2.54 2.07 1.6 1.6 1.64 2.533333333 1.613333333 69.1 68.15 68.95 94.64666667 68.73333333 0.127840813 -0.465809763 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 102633763 102633763 'Gm31513' mRNA 14.64 8.62 9.85 0.15 0.09 0.11 0.17 0.04 0.07 0.116666667 0.093333333 18.8 4.2 7.15 11.03666667 10.05 0.913490217 -0.1182116 102633782 102633782 'Gm31526' mRNA 25.61 20.32 16.29 0.63 0.49 0.43 0.47 0.51 0.48 0.516666667 0.486666667 21.94 22.96 21.73 20.74 22.21 0.929247568 0.063084132 102633783 102633783 'LOC102633783' mRNA 1 0 0 0.08 0 0 0.11 0.07 0.04 0.026666667 0.073333333 1.58 1.05 0.52 0.333333333 1.05 0.863090843 0.881254164 102633800 102633800 'Gm12770' mRNA 0 1 1.99 0 0.16 0.35 0.14 0 0.3 0.17 0.146666667 1 0 2 0.996666667 1 0.872036916 0.557526301 102633809 102633809 'Gm3785' mRNA 9 11.4 9.4 1.89 2.41 2.1 1.61 3.83 2.71 2.133333333 2.716666667 8.7 20 14.02 9.933333333 14.24 0.556421822 0.531573185 102633888 102633888 'Gm31606' mRNA 109.46 102.89 84.76 0.05 0.05 0.04 0.02 0.03 0.03 0.046666667 0.026666667 59.67 78.46 74.18 99.03666667 70.77 0.101432919 -0.489170821 102633951 102633951 'Gm31649' mRNA 2.01 0 0 0.15 0 0 0 0 0 0.05 0 0 0 0 0.67 0 0.749855753 -1.843955659 102633968 102633968 'Gm31665' mRNA 5 0 3 0.04 0 0.03 0.07 0.04 0.04 0.023333333 0.05 10 6 5 2.666666667 7 0.330939802 1.366914544 102634078 102634078 'LOC102634078' mRNA 511.02 446.11 465.41 14.08 12.11 13.6 6.83 6.63 6.58 13.26333333 6.68 284.93 270.22 265.65 474.18 273.6 2.16E-09 -0.8085954 102634296 102634296 'Gm4779' mRNA 5.43 6 2 0.15 0.17 0.06 0.2 0.28 0.1 0.126666667 0.193333333 8 11 4 4.476666667 7.666666667 0.507117683 0.82830922 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102634333 102634333 '1110002E22Rik' mRNA 20 26 11 0.11 0.14 0.06 0.07 0.08 0.08 0.103333333 0.076666667 16 16 17 19 16.33333333 0.791125883 -0.216327191 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102634429 102634429 'Gm6569' mRNA 0 2 0 0 0.19 0 0 0 0 0.063333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102634532 102634532 'Gm3642' mRNA 2.22 0.99 3 0.23 0.1 0.33 0 0.09 0 0.22 0.03 0 0.99 0 2.07 0.33 0.362613802 -3.224786805 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102634715 102634715 'Gm32234' mRNA 289.49 332.92 286.94 1.21 1.37 1.27 0.87 0.77 1.09 1.283333333 0.91 240.13 206.41 290.63 303.1166667 245.7233333 0.089078649 -0.31209719 102634778 102634778 'Gm32280' mRNA 3 6 2 0.11 0.21 0.08 0.41 0.29 0.32 0.133333333 0.34 13 9 10 3.666666667 10.66666667 0.138179155 1.538154067 102634841 102634841 'Gm38469' mRNA 16 12 10 0.44 0.32 0.29 0.1 0.12 0.27 0.35 0.163333333 4 5 11 12.66666667 6.666666667 0.320457027 -0.929706818 102634987 102634987 'Gm32436' mRNA 6 5 3 0.63 0.52 0.34 0.55 0.38 0.19 0.496666667 0.373333333 6 4 2 4.666666667 4 0.877055954 -0.22934223 102635068 102635068 'Gm24392' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 102635181 102635181 'Gm32584' mRNA 6 6 8 0.24 0.24 0.34 0.31 0.18 0.11 0.273333333 0.2 9 5 3 6.666666667 5.666666667 0.860265279 -0.259303177 102635315 102635315 'Gm32687' mRNA 178.32 152.12 151.03 3.48 3.02 3.2 1.6 1.37 1.13 3.233333333 1.366666667 95.79 81.66 59.85 160.49 79.1 2.25E-05 -1.046250473 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 102635360 102635360 'Gm32719' mRNA 55.73 37.53 32.16 0.75 0.5 0.46 0.34 0.29 0.49 0.57 0.373333333 29.56 24.68 40.87 41.80666667 31.70333333 0.408801388 -0.42170128 102635385 102635385 'Gm32742' mRNA 7750 7541 6906 61.25 58.59 57.9 4.84 4.03 4.58 59.24666667 4.483333333 705 574 646 7399 641.6666667 0 -3.538966671 102635496 102635496 'Malrd1' mRNA 7 0 0 0.05 0 0 0.01 0 0 0.016666667 0.003333333 1 0 0 2.333333333 0.333333333 0.405619498 -2.688796779 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0042632///cholesterol homeostasis+++GO:0050714///positive regulation of protein secretion+++GO:0070858///negative regulation of bile acid biosynthetic process 102635552 102635552 'Gm32856' mRNA 548 529.44 484.67 8.08 7.33 7.48 2.38 2.24 2.29 7.63 2.303333333 200.66 181.25 179.65 520.7033333 187.1866667 3.04E-28 -1.489923713 102635566 102635566 'Gm17434' mRNA 17.21 10.97 13.67 0.08 0.05 0.07 0.03 0.01 0 0.066666667 0.013333333 6.98 2 0 13.95 2.993333333 0.028701697 -2.345669805 102635595 102635595 'Gm32886' mRNA 1 0 0 0.36 0 0 0 0 0 0.12 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 102635694 102635694 'Gm32966' mRNA 1 0 0 0.1 0 0 0.18 0.13 0 0.033333333 0.103333333 2 1 0 0.333333333 1 0.735536859 1.457609237 102635744 102635744 'Gm28729' mRNA 23 19 18 0.63 0.51 0.48 0.13 0.07 0 0.54 0.066666667 5 3 0 20 2.666666667 0.001201057 -2.921697378 102635802 102635802 'Gm33049' mRNA 5.06 2.03 0 0.45 0.18 0 0.08 0.08 0.16 0.21 0.106666667 1.01 1.02 2.04 2.363333333 1.356666667 0.752944406 -0.789449962 102635845 102635845 'Gm33084' mRNA 0 1 0 0 0.84 0 0 0 0 0.28 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 102635879 102635879 '4933407O12Rik' mRNA 3 2 8 0.16 0.11 0.46 0.14 0.34 0.49 0.243333333 0.323333333 3 7 10 4.333333333 6.666666667 0.680723497 0.590649307 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102635944 102635944 'Gm33153' mRNA 16.42 37.38 28.06 0.1 0.23 0.18 0.2 0.19 0.14 0.17 0.176666667 37.72 33.7 25.51 27.28666667 32.31 0.742155911 0.217137986 102635990 102635990 'LOC102635990' mRNA 3.01 1 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 1.336666667 0 0.489543081 -2.838520661 GO:0016021///integral component of membrane 102636051 102636051 'Tmem274' mRNA 17 16 14 2.99 2.82 2.61 0.46 1.12 0.32 2.806666667 0.633333333 3 7 2 15.66666667 4 0.025597098 -1.97414613 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102636082 102636082 'Gm8251' mRNA 4 1 6 0.01 0 0.02 0.05 0.04 0.03 0.01 0.04 22 16 14 3.666666667 17.33333333 0.012393988 2.210574671 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102636203 102636203 '4930519L02Rik' mRNA 141.22 128.41 127.96 17.15 15.51 16.49 6.61 6.37 8.48 16.38333333 7.153333333 62.15 58.25 76.84 132.53 65.74666667 6.17E-05 -1.026064965 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102636379 102636379 'Gm14037' mRNA 2 1 4.66 1.14 0.59 2.85 1.55 2.13 2.15 1.526666667 1.943333333 3 4 4 2.553333333 3.666666667 0.741082698 0.621937082 102636475 102636475 'Gm33532' mRNA 159.18 123.96 102.34 1.42 1.09 0.97 0.16 0.11 0.15 1.16 0.14 21.23 14.4 18.75 128.4933333 18.12666667 3.59E-17 -2.865188651 102636558 102636558 'LOC102636558' mRNA 4.55 1.41 2.9 0.4 0.12 0.27 1.68 1.32 1.96 0.263333333 1.653333333 21.58 16.57 24.41 2.953333333 20.85333333 5.22E-04 3.110907051 102636661 102636661 'Gm33666' mRNA 1 2 2 0.15 0.29 0.31 0.76 0.52 0.8 0.25 0.693333333 6 3.99 6.08 1.666666667 5.356666667 0.317724956 1.565538252 102636878 102636878 'Gm33828' mRNA 0 1 0 0 0.05 0 0 0 0.05 0.016666667 0.016666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 102636907 102636907 'Gm4275' mRNA 14.08 17 16.67 0.17 0.2 0.21 0.24 0.15 0.21 0.193333333 0.2 23 14 19 15.91666667 18.66666667 0.764362663 0.236856634 102636909 102636909 'Gm33851' mRNA 2 3 0 0.12 0.17 0 0.15 0.05 0 0.096666667 0.066666667 3 1 0 1.666666667 1.333333333 0.91037533 -0.314475571 102636931 102636931 'Gm33869' mRNA 18 23 32 0.13 0.16 0.24 0.12 0.12 0.12 0.176666667 0.12 20 19 19 24.33333333 19.33333333 0.599874516 -0.3538083 102637020 102637020 'Gm33933' mRNA 4.38 0 0 0.12 0 0 0.15 0.2 0.13 0.04 0.16 6.1 8.05 5.02 1.46 6.39 0.166457323 2.254796919 102637087 102637087 'Gm33989' mRNA 1224.75 1227.59 1120.26 3.56 3.47 3.51 2.43 2.09 2.12 3.513333333 2.213333333 956.57 809.58 835.74 1190.866667 867.2966667 1.96E-07 -0.469668936 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102637129 102637129 'Gm12854' mRNA 148.98 124.15 158.15 5.02 4.12 5.65 11.85 13.26 13.13 4.93 12.74666667 404.3 441.44 433.41 143.76 426.3833333 2.32E-21 1.557144173 102637366 102637366 'Gm10037' mRNA 17 11 14 0.86 0.34 0.35 0.11 0.1 0.12 0.516666667 0.11 5.98 6 4 14 5.326666667 0.085557582 -1.498313237 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 102637505 102637505 'Gm34296' mRNA 0 1 1 0 0.06 0.06 0 0.05 0 0.04 0.016666667 0 1 0 0.666666667 0.333333333 0.861179337 -0.920394634 102637507 102637507 'Gm34298' mRNA 2 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 102637511 102637511 'Strit1' mRNA 7 7 6 3.62 3.74 3.31 0 0.49 0 3.556666667 0.163333333 0 1 0 6.666666667 0.333333333 0.019058174 -4.226934442 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane GO:0005515///protein binding+++GO:0008047///enzyme activator activity GO:0031449///regulation of slow-twitch skeletal muscle fiber contraction+++GO:0050790///regulation of catalytic activity+++GO:0090280///positive regulation of calcium ion import+++GO:0106134///positive regulation of cardiac muscle cell contraction+++GO:1901894///regulation of calcium-transporting ATPase activity+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:1902082///positive regulation of calcium ion import into sarcoplasmic reticulum 102637513 102637513 'Gm34303' mRNA 2 2 1 0.39 0.4 0.21 0.17 0.18 0.18 0.333333333 0.176666667 1 1 1 1.666666667 1 0.787532877 -0.737059142 102637572 102637572 'Gm38499' mRNA 11 17 12 0.47 0.71 0.54 0.26 0.42 0.61 0.573333333 0.43 7 11 16 13.33333333 11.33333333 0.809260148 -0.238585304 102637593 102637593 'Gm34362' mRNA 37 25.24 23 0.69 0.47 0.46 0.26 0.22 0.4 0.54 0.293333333 16 13 24 28.41333333 17.66666667 0.250094351 -0.689182302 102637806 102637806 'LOC102637806' mRNA 3 1.04 1.02 0.12 0.04 0.04 0 0.14 0 0.066666667 0.046666667 0 4 0 1.686666667 1.333333333 0.914422837 -0.304474374 102637808 102637808 'Gm21976' mRNA 2 4 0 0.08 0.16 0 0.18 0.07 0 0.08 0.083333333 5 2 0 2 2.333333333 0.925489235 0.231201231 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 102637839 102637839 'Gm10476' mRNA 16.72 22.68 8.54 0.39 0.66 0.21 0.85 0.24 0.48 0.42 0.523333333 14.92 9.27 17.21 15.98 13.8 0.837505556 -0.199772616 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102637899 102637899 'Gm34595' mRNA 250.23 198.23 269.77 1.8 1.4 2.06 0.78 0.78 0.77 1.753333333 0.776666667 124.86 122.44 119.06 239.41 122.12 1.48E-06 -0.991641301 102637973 102637973 'Gm34653' mRNA 1624.5 1516.25 1632.5 56.77 52.24 60.5 5.16 4.86 6.58 56.50333333 5.533333333 168.92 158.91 211.38 1591.083333 179.7366667 5.96E-155 -3.165433025 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation 102638047 102638047 'LOC102638047' mRNA 19.66 7.99 13.73 0.66 0.27 0.44 1.15 1.33 1.51 0.456666667 1.33 38.03 43.03 47.12 13.79333333 42.72666667 0.001060739 1.702036143 102638083 102638083 'Ccdc188' mRNA 0 1 3 0 0.04 0.11 0 0.04 0 0.05 0.013333333 0 1 0 1.333333333 0.333333333 0.593300767 -1.948768704 GO:0005575///cellular_component+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 102638268 102638268 '1700014D04Rik' mRNA 1 2 2 0.02 0.03 0.03 0.07 0 0 0.026666667 0.023333333 5 0 0 1.666666667 1.666666667 0.994509114 -0.044028947 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102638382 102638382 'Gm34962' mRNA 51.23 62.23 60.23 0.81 0.97 1.01 1.18 1.23 1.57 0.93 1.326666667 86.03 87.13 110.38 57.89666667 94.51333333 0.021972494 0.697868709 102638498 102638498 'Gm15732' mRNA 2 8 3 0.25 0.98 0.39 0.11 0.66 0 0.54 0.256666667 1 6 0 4.333333333 2.333333333 0.650254545 -0.877882471 102638514 102638514 'Gm35060' mRNA 0 0 1 0 0 0.03 0 0 0.04 0.01 0.013333333 0 0 2 0.333333333 0.666666667 0.863090843 0.890621057 GO:0016020///membrane+++GO:0016021///integral component of membrane 102638541 102638541 'Gm35078' mRNA 0 0 1 0 0 0.18 0 0 0 0.06 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 102638555 102638555 'Gm38510' mRNA 5.86 6.07 2.4 0.1 0.17 0.05 0.31 0.53 0.42 0.106666667 0.42 20.36 30.82 26.16 4.776666667 25.78 5.21E-04 2.550084636 102638674 102638674 'Gm14428' mRNA 7 4.7 7 0.84 0.56 0.89 0.32 0.11 0.43 0.763333333 0.286666667 3.03 1 4 6.233333333 2.676666667 0.394084956 -1.192736748 102638847 102638847 'Gm35315' mRNA 91.96 51.56 54.9 1.37 0.74 0.82 0.49 0.5 0.62 0.976666667 0.536666667 42.4 39.04 47.5 66.14 42.98 0.112742854 -0.623362681 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 102638882 102638882 'Gm35339' mRNA 50 43 45 0.71 0.41 0.59 0.36 0.34 0.19 0.57 0.296666667 37 28 20 46 28.33333333 0.112840278 -0.714260896 102638888 102638888 'Gm20346' mRNA 68.63 56.68 43.22 3.56 2.91 2.38 1.33 1.05 1.19 2.95 1.19 29.39 22.74 25.48 56.17666667 25.87 0.005233789 -1.143181472 102638918 102638918 'Gm35364' mRNA 10.69 5.69 8 0.6 0.29 0.44 0.33 0.21 0.35 0.443333333 0.296666667 5.54 4.56 5.65 8.126666667 5.25 0.541291783 -0.732952648 102639021 102639021 'Gm3993' mRNA 1.14 9.93 1.05 0.06 0.48 0.06 0.29 0.1 0.23 0.2 0.206666667 6.77 2.36 4.09 4.04 4.406666667 0.941497603 0.134229494 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102639132 102639132 'Gm21885' mRNA 4 1 1 0.33 0.08 0.09 0.14 0 0 0.166666667 0.046666667 2 0 0 2 0.666666667 0.57921052 -1.606224769 102639178 102639178 'Gm35549' mRNA 0 1.56 0 0 0.15 0 0 0 0 0.05 0 0 0 0 0.52 0 0.863090843 -0.97353728 102639229 102639229 'Gm35588' mRNA 0 1 2 0 0.02 0.04 0.02 0 0 0.02 0.006666667 1 0 0 1 0.333333333 0.718811751 -1.5240122 102639543 102639543 'Ifi206' mRNA 29.28 16 26.22 0.47 0.25 0.45 3.85 3.46 3.63 0.39 3.646666667 274.66 240.41 250.57 23.83333333 255.2133333 1.62E-38 3.412898135 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002218///activation of innate immune response+++GO:0030224///monocyte differentiation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042149///cellular response to glucose starvation+++GO:0043392///negative regulation of DNA binding+++GO:0045071///negative regulation of viral genome replication+++GO:0045824///negative regulation of innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0071479///cellular response to ionizing radiation+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:2000117///negative regulation of cysteine-type endopeptidase activity" 102639577 102639577 'Gm35857' mRNA 2.01 2.02 3.01 0.66 0.67 1.05 2.05 1.82 1.22 0.793333333 1.696666667 7.03 6.05 4.02 2.346666667 5.7 0.377275234 1.258974311 102639598 102639598 'Gm14296' mRNA 176.56 97.42 128.9 2.47 1.31 1.93 0.77 1.27 2.91 1.903333333 1.65 63.3 102.18 231.31 134.2933333 132.2633333 0.981537408 -0.025443249 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 102639650 102639650 'Vamp9' mRNA 12 24 17.09 0.51 1.24 0.62 0.27 0.73 0.61 0.79 0.536666667 10.01 11 17.97 17.69666667 12.99333333 0.540313858 -0.487663509 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0016192///vesicle-mediated transport 102639653 102639653 'Gm2007' mRNA 279.2 124.81 163.41 2.26 1.05 1.29 1.57 1.12 1.57 1.533333333 1.42 219.2 162.66 196.74 189.14 192.8666667 0.969524298 0.015003502 GO:0005575///cellular_component GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated" 102639700 102639700 'Gm21297' mRNA 70.19 69.3 47.93 1.27 1.24 0.92 0.28 0.5 0.51 1.143333333 0.43 18.08 30.96 31.16 62.47333333 26.73333333 0.002329952 -1.236151152 102639713 102639713 'Gm14421' mRNA 151.3 167.38 167.22 3.17 3.46 3.72 1.91 2.51 2.1 3.45 2.173333333 104.81 134.24 111.52 161.9666667 116.8566667 0.036830757 -0.48605375 102639802 102639802 'Gm36028' mRNA 10 0 2 0.55 0 0.12 0.19 0.1 0.4 0.223333333 0.23 4 2 8 4 4.666666667 0.901147071 0.217761863 GO:0009897///external side of plasma membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 102639868 102639868 'Gm36079' mRNA 0 1.03 0 0 0.06 0 0.24 0.19 0.42 0.02 0.283333333 4.74 3.74 8.1 0.343333333 5.526666667 0.057461872 3.791419473 GO:0038023///signaling receptor activity 102639870 102639870 'Gm38523' mRNA 7 7 9.04 0.38 0.37 0.53 0.07 0.15 0.04 0.426666667 0.086666667 1.54 3 0.78 7.68 1.773333333 0.071999642 -2.536584853 102639919 102639919 'Gm36118' mRNA 7 10 3 0.24 0.33 0.11 0.29 0.3 0.52 0.226666667 0.37 10 10 17 6.666666667 12.33333333 0.351018249 0.893018613 102639922 102639922 'Gm10157' mRNA 8.4 12.62 15.56 1.09 1.64 2.15 1.64 0.32 1.11 1.626666667 1.023333333 14.39 2.74 9.38 12.19333333 8.836666667 0.633537466 -0.516950692 102640003 102640003 'Gm36182' mRNA 10.78 5.03 8.33 0.09 0.04 0.07 0.01 0 0.01 0.066666667 0.006666667 1 0 1 8.046666667 0.666666667 0.027639214 -3.543929352 102640043 102640043 'Gm36210' mRNA 8 4 8 0.11 0.05 0.12 0.08 0.06 0.05 0.093333333 0.063333333 7 5 4 6.666666667 5.333333333 0.800369356 -0.345296661 102640165 102640165 'Gm36298' mRNA 100.64 109.7 118.02 2.61 2.8 3.24 2.1 1.39 2.37 2.883333333 1.953333333 93.21 60.15 101.71 109.4533333 85.02333333 0.2171144 -0.381777333 102640171 102640171 'Gm38525' mRNA 5.12 9.82 5.95 0.14 0.44 0.2 2.52 1.36 1 0.26 1.626666667 75.54 41.27 40.46 6.963333333 52.42333333 7.92E-08 3.024231177 102640263 102640263 'Gm36375' mRNA 168 202 165 0.3 0.35 0.31 0.16 0.22 0.24 0.32 0.206666667 104 141.03 149.59 178.3333333 131.54 0.055154797 -0.448063043 102640268 102640268 'Gm2956' mRNA 10.37 13.77 6.83 0.42 0.49 0.32 0.42 0.56 0.22 0.41 0.4 11.49 15.4 6.45 10.32333333 11.11333333 0.886537466 0.143802264 102640376 102640376 'Gm36448' mRNA 7 8.01 5 0.83 0.94 0.63 0 0.11 0.11 0.8 0.073333333 0 1 1.01 6.67 0.67 0.046500609 -3.319580942 102640673 102640673 'Gm5165' mRNA 348.88 365.99 339.44 7.96 8.22 8.21 4.26 5.29 4.93 8.13 4.826666667 214.66 260.53 240.76 351.4366667 238.65 2.73E-04 -0.56876382 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 102640707 102640707 'Gm15793' mRNA 0 2.12 0.72 0 0.25 0.09 0 0 0.23 0.113333333 0.076666667 0 0 2.14 0.946666667 0.713333333 0.998591786 0.035579107 102640710 102640710 'Gm36712' mRNA 117.04 121 140 2.18 2.22 2.77 1.93 1.81 1.82 2.39 1.853333333 119 109.05 109.05 126.0133333 112.3666667 0.523747369 -0.1820442 102640722 102640722 'Gm36722' mRNA 53 50 45 0.43 0.58 0.39 0.17 0.17 0.37 0.466666667 0.236666667 23 21 33 49.33333333 25.66666667 0.026384706 -0.952148035 102640809 102640809 'Gm36789' mRNA 3 0 0 0.07 0 0 0.04 0.02 0.02 0.023333333 0.026666667 2 1 1 1 1.333333333 0.890662181 0.41803738 102640913 102640913 'Gm36864' mRNA 2 1 9 0.05 0.05 0.28 0.07 0.1 0.04 0.126666667 0.07 3 3 1 4 2.333333333 0.655860993 -0.832603395 GO:0016020///membrane+++GO:0016021///integral component of membrane 102640920 102640920 'Pvrig' mRNA 1 1 1 0.06 0.06 0.07 0.17 0.46 0.4 0.063333333 0.343333333 3 8 7 1 6 0.101269742 2.581044207 GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0038023///signaling receptor activity GO:0050860///negative regulation of T cell receptor signaling pathway 102641157 102641157 'Gm38538' mRNA 11.45 13.81 8.75 0.58 0.69 0.47 0.36 0.29 0.23 0.58 0.293333333 8.24 6.5 5.09 11.33666667 6.61 0.444555659 -0.758661501 102641752 102641752 'Gm38574' mRNA 27.66 30.46 17.77 3.09 3.39 2.11 1.97 2.65 3.46 2.863333333 2.693333333 20.15 26.33 34.06 25.29666667 26.84666667 0.863090843 0.112663468 03410///Base excision repair+++04140///Autophagy - animal+++04217///Necroptosis+++04613///Neutrophil extracellular trap formation 102642386 102642386 'Gm6871' mRNA 0 1 0 0 0.02 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 102643076 102643076 'Percc1' mRNA 92 83 121.93 1.81 1.61 2.54 0.53 0.47 0.56 1.986666667 0.52 31 27 32 98.97666667 30 2.16E-07 -1.738781748 GO:0007275///multicellular organism development+++GO:0035883///enteroendocrine cell differentiation+++GO:0048546///digestive tract morphogenesis 102643210 102643210 'Gm38664' mRNA 14 13 11 0.25 0.23 0.21 0.22 0.06 0.13 0.23 0.136666667 14 4 8 12.66666667 8.666666667 0.556887025 -0.564427576 102644 102644 'Oaf' mRNA 186 170 33 4.36 3.92 0.82 1.79 4.4 3.79 3.033333333 3.326666667 88 211 180 129.6666667 159.6666667 0.759117591 0.325655513 GO:0003674///molecular_function GO:0008150///biological_process 102657 102657 'Cd276' mRNA 339 368 284 5.8 6.19 5.15 6.79 7.76 7.17 5.713333333 7.24 457 510 467 330.3333333 478 1.28E-04 0.52633001 04514///Cell adhesion molecules GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding GO:0001817///regulation of cytokine production+++GO:0030501///positive regulation of bone mineralization+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050776///regulation of immune response+++GO:0050852///T cell receptor signaling pathway 102680 102680 'Slc6a20a' mRNA 5 2 7 0.15 0.06 0.22 0.11 0.27 0.08 0.143333333 0.153333333 4 10 3 4.666666667 5.666666667 0.863090843 0.25827238 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005298///proline:sodium symporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015199///amino-acid betaine transmembrane transporter activity+++GO:0015293///symporter activity GO:0006865///amino acid transport+++GO:0015816///glycine transport+++GO:0015824///proline transport+++GO:0015838///amino-acid betaine transport+++GO:0035524///proline transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:1904271///L-proline import across plasma membrane+++GO:1905647///proline import across plasma membrane 102693 102693 'Phldb1' mRNA 1679 1579 1416 15.5 14.32 13.66 12.33 11.62 11.01 14.49333333 11.65333333 1544 1419 1302 1558 1421.666667 0.130065048 -0.142560969 GO:0045180///basal cortex GO:0003674///molecular_function GO:0010470///regulation of gastrulation+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis 102747 102747 'Lrrc49' mRNA 460 532 500 9.29 10.13 10.22 4.94 4.67 4.17 9.88 4.593333333 284 269 237 497.3333333 263.3333333 1.72E-11 -0.930188934 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0003674///molecular_function GO:0018095///protein polyglutamylation+++GO:0036158///outer dynein arm assembly 102774 102774 'Bbs4' mRNA 1055 1158 1036 24.08 25.86 24.91 12.68 12.6 12.17 24.95 12.48333333 644 631 598 1083 624.3333333 4.65E-18 -0.805569894 GO:0000242///pericentriolar material+++GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0034451///centriolar satellite+++GO:0034464///BBSome+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium "GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0034452///dynactin binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" GO:0000226///microtubule cytoskeleton organization+++GO:0000281///mitotic cytokinesis+++GO:0001764///neuron migration+++GO:0001843///neural tube closure+++GO:0001895///retina homeostasis+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0007098///centrosome cycle+++GO:0007286///spermatid development+++GO:0007608///sensory perception of smell+++GO:0008104///protein localization+++GO:0010629///negative regulation of gene expression+++GO:0015031///protein transport+++GO:0016358///dendrite development+++GO:0019216///regulation of lipid metabolic process+++GO:0021591///ventricular system development+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030030///cell projection organization+++GO:0030534///adult behavior+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032465///regulation of cytokinesis+++GO:0033210///leptin-mediated signaling pathway+++GO:0033365///protein localization to organelle+++GO:0034260///negative regulation of GTPase activity+++GO:0034454///microtubule anchoring at centrosome+++GO:0035176///social behavior+++GO:0035845///photoreceptor cell outer segment organization+++GO:0038108///negative regulation of appetite by leptin-mediated signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0044321///response to leptin+++GO:0045444///fat cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0045724///positive regulation of cilium assembly+++GO:0046548///retinal rod cell development+++GO:0048854///brain morphogenesis+++GO:0051457///maintenance of protein location in nucleus+++GO:0051492///regulation of stress fiber assembly+++GO:0060271///cilium assembly+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:0060324///face development+++GO:0060613///fat pad development+++GO:0061512///protein localization to cilium+++GO:0071539///protein localization to centrosome+++GO:1902855///regulation of non-motile cilium assembly+++GO:1903546///protein localization to photoreceptor outer segment+++GO:1905515///non-motile cilium assembly 102791 102791 'Tcta' mRNA 1579 1590 1556 50.61 50.19 52.88 45.96 46.8 44.97 51.22666667 45.91 1649 1640 1561 1575 1616.666667 0.813812421 0.02557471 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0045671///negative regulation of osteoclast differentiation+++GO:0072675///osteoclast fusion 102857 102857 'Slc6a8' mRNA 581 530 499 7.91 7.1 7.21 9.13 8.72 9.16 7.406666667 9.003333333 772 720 750 536.6666667 747.3333333 1.12E-05 0.466865967 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005308///creatine transmembrane transporter activity+++GO:0005309///creatine:sodium symporter activity+++GO:0015220///choline transmembrane transporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006836///neurotransmitter transport+++GO:0015871///choline transport+++GO:0015881///creatine transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071705///nitrogen compound transport+++GO:1990403///embryonic brain development 102866 102866 'Pls3' mRNA 1408 1483 1491 24.53 25.44 27.54 36.7 37.29 32.66 25.83666667 35.55 2423 2403 2087 1460.666667 2304.333333 2.13E-14 0.644340357 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0031594///neuromuscular junction+++GO:0032420///stereocilium+++GO:0032432///actin filament bundle GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0098699///structural constituent of presynaptic actin cytoskeleton GO:0051017///actin filament bundle assembly+++GO:0051639///actin filament network formation+++GO:0060348///bone development+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0099140///presynaptic actin cytoskeleton organization 102871 102871 'Radx' mRNA 7 8 5 0.1 0.12 0.08 0.28 0.2 0.36 0.1 0.28 22 15 28 6.666666667 21.66666667 0.018100153 1.693059366 GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding GO:0006282///regulation of DNA repair+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 102902673 102902673 'Gm21992' mRNA 54.81 10.17 47.4 1.09 0.23 0.98 0.58 1.08 0.38 0.766666667 0.68 32.98 61.2 20.33 37.46 38.17 0.998591786 0.005293674 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008270///zinc ion binding+++GO:0030332///cyclin binding+++GO:0035198///miRNA binding+++GO:0036002///pre-mRNA binding+++GO:0097157///pre-mRNA intronic binding+++GO:0097158///pre-mRNA intronic pyrimidine-rich binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0002190///cap-independent translational initiation+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0031016///pancreas development+++GO:0032055///negative regulation of translation in response to stress+++GO:0032922///circadian regulation of gene expression+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0035883///enteroendocrine cell differentiation+++GO:0042593///glucose homeostasis+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045727///positive regulation of translation+++GO:0045947///negative regulation of translational initiation+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046685///response to arsenic-containing substance+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0097167///circadian regulation of translation" 102920 102920 'Cenpi' mRNA 72.85 53.87 72.69 1.02 0.75 1.08 3.88 4.09 4.45 0.95 4.14 309.17 319.13 342.41 66.47 323.57 3.83E-30 2.285798901 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0016604///nuclear body" GO:0003674///molecular_function GO:0008150///biological_process+++GO:0034508///centromere complex assembly 102954 102954 'Nudt10' mRNA 29.71 20.43 11.41 0.9 0.56 0.37 0.87 0.52 0.61 0.61 0.666666667 32.6 20.78 21.35 20.51666667 24.91 0.706410296 0.278941847 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000298///endopolyphosphatase activity+++GO:0008486///diphosphoinositol-polyphosphate diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0034431///bis(5'-adenosyl)-hexaphosphatase activity+++GO:0034432///bis(5'-adenosyl)-pentaphosphatase activity+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0052840///inositol diphosphate tetrakisphosphate diphosphatase activity+++GO:0052842///inositol diphosphate pentakisphosphate diphosphatase activity GO:0071543///diphosphoinositol polyphosphate metabolic process+++GO:1901907///diadenosine pentaphosphate catabolic process+++GO:1901909///diadenosine hexaphosphate catabolic process+++GO:1901911///adenosine 5'-(hexahydrogen pentaphosphate) catabolic process 103080 103080 'Septin10' mRNA 225 264 250 5.76 6.64 6.78 9.76 10.74 10.86 6.393333333 10.45333333 437 470 471 246.3333333 459.3333333 3.55E-10 0.887491321 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0031105///septin complex+++GO:0032153///cell division site GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0034613///cellular protein localization+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis 103098 103098 'Slc6a15' mRNA 456 440 485 6.69 6.43 7.64 3.5 3.91 3.67 6.92 3.693333333 273 293 277 460.3333333 281 2.27E-07 -0.72590484 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005298///proline:sodium symporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006836///neurotransmitter transport+++GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015820///leucine transport+++GO:0015824///proline transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1903825///organic acid transmembrane transport 103135 103135 'Pan2' mRNA 1568 1498 1473 18.71 17.49 18.33 11.43 11.03 10.38 18.17666667 10.94666667 1121 1044 975.85 1513 1046.95 9.28E-11 -0.544080012 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031251///PAN complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000291///nuclear-transcribed mRNA catabolic process, exonucleolytic+++GO:0006397///mRNA processing+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly" 103136 103136 'Pwp1' mRNA 634 698 710 13.66 14.81 16.23 17.59 17.55 20.3 14.9 18.48 939 915 1049 680.6666667 967.6666667 5.77E-06 0.494143659 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus GO:1990889///H4K20me3 modified histone binding GO:0006364///rRNA processing+++GO:0033140///negative regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0034773///histone H4-K20 trimethylation+++GO:0042254///ribosome biogenesis+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:2000738///positive regulation of stem cell differentiation 103140 103140 'Gstt3' mRNA 1192 1230 1160 36.48 37.09 37.67 31.57 35.47 35.45 37.08 34.16333333 1185 1300 1288 1194 1257.666667 0.558881077 0.064508109 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity GO:0006749///glutathione metabolic process 103142 103142 'Rdh9' mRNA 38.56 64.42 48.24 0.79 1.3 1.05 0.5 0.55 0.64 1.046666667 0.563333333 28.19 30.18 35 50.40666667 31.12333333 0.107160479 -0.698393703 00830///Retinol metabolism GO:0005789///endoplasmic reticulum membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:1900054///positive regulation of retinoic acid biosynthetic process 103149 103149 'Upb1' mRNA 16 16 17 0.29 0.28 0.33 0.22 0.14 0.34 0.3 0.233333333 14 9 21 16.33333333 14.66666667 0.857024457 -0.170130626 00240///Pyrimidine metabolism+++00410///beta-Alanine metabolism+++00770///Pantothenate and CoA biosynthesis+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0003837///beta-ureidopropionase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0042803///protein homodimerization activity" GO:0001889///liver development+++GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0006807///nitrogen compound metabolic process+++GO:0008152///metabolic process+++GO:0019482///beta-alanine metabolic process+++GO:0019483///beta-alanine biosynthetic process+++GO:0033396///beta-alanine biosynthetic process via 3-ureidopropionate+++GO:0046050///UMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process+++GO:0046135///pyrimidine nucleoside catabolic process+++GO:0051260///protein homooligomerization+++GO:0051289///protein homotetramerization 103161 103161 'Apof' mRNA 76.26 104.5 115.5 1.84 2.48 2.95 5.17 5.24 5.3 2.423333333 5.236666667 246.63 244.32 245.04 98.75333333 245.33 6.37E-10 1.300885503 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034362///low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle GO:0003674///molecular_function GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006869///lipid transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0033344///cholesterol efflux 103172 103172 'Chchd10' mRNA 12827 12430 11947 666.66 637.88 658.27 568.87 591.56 553.4 654.27 571.2766667 12564 12756 11823 12401.33333 12381 0.863090843 -0.013658905 05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0061617///MICOS complex GO:0005515///protein binding GO:0006119///oxidative phosphorylation+++GO:0007005///mitochondrion organization+++GO:0030322///stabilization of membrane potential+++GO:0031930///mitochondria-nucleus signaling pathway+++GO:0051457///maintenance of protein location in nucleus+++GO:0065003///protein-containing complex assembly+++GO:0090144///mitochondrial nucleoid organization+++GO:0099558///maintenance of synapse structure+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1903109///positive regulation of mitochondrial transcription+++GO:1903852///positive regulation of cristae formation 103199 103199 'Fig4' mRNA 619 557 575 10.36 9.17 10.21 9.92 9.5 9.1 9.913333333 9.506666667 682 638 606 583.6666667 642 0.338600766 0.124586177 00562///Inositol phosphate metabolism+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity+++GO:0043813///phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity" GO:0007033///vacuole organization+++GO:0007626///locomotory behavior+++GO:0010976///positive regulation of neuron projection development+++GO:0031642///negative regulation of myelination+++GO:0032288///myelin assembly+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0043473///pigmentation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048666///neuron development 103213 103213 'Traf3ip2' mRNA 592 633 577 12.55 13.3 13.21 10.55 10.08 10.24 13.02 10.29 542 519 510 600.6666667 523.6666667 0.076690669 -0.209165149 04218///Cellular senescence+++04657///IL-17 signaling pathway GO:0005634///nucleus+++GO:0031410///cytoplasmic vesicle GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0001768///establishment of T cell polarity+++GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001822///kidney development+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002269///leukocyte activation involved in inflammatory response+++GO:0002334///transitional two stage B cell differentiation+++GO:0002344///B cell affinity maturation+++GO:0002367///cytokine production involved in immune response+++GO:0002377///immunoglobulin production+++GO:0002447///eosinophil mediated immunity+++GO:0002534///cytokine production involved in inflammatory response+++GO:0006606///protein import into nucleus+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006959///humoral immune response+++GO:0007507///heart development+++GO:0009410///response to xenobiotic stimulus+++GO:0010467///gene expression+++GO:0016567///protein ubiquitination+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019724///B cell mediated immunity+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0023035///CD40 signaling pathway+++GO:0030217///T cell differentiation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0034504///protein localization to nucleus+++GO:0038173///interleukin-17A-mediated signaling pathway+++GO:0042092///type 2 immune response+++GO:0042110///T cell activation+++GO:0042119///neutrophil activation+++GO:0042493///response to drug+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043588///skin development+++GO:0048255///mRNA stabilization+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0070254///mucus secretion+++GO:0070534///protein K63-linked ubiquitination+++GO:0071345///cellular response to cytokine stimulus+++GO:0072538///T-helper 17 type immune response+++GO:0097398///cellular response to interleukin-17+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0110012///protein localization to P-body+++GO:1990959///eosinophil homeostasis 103220 103220 'Ttc41' mRNA 161.24 196.28 200.72 3.05 3.75 3.71 1.48 1.69 1.34 3.503333333 1.503333333 91.21 104.13 79.87 186.08 91.73666667 5.37E-06 -1.037301321 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 103236 103236 'Csnk1g2' mRNA 450 463 394 11.09 11.26 10.4 9.79 9.84 11.13 10.91666667 10.25333333 456 447 504 435.6666667 469 0.528766809 0.097287097 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005938///cell cortex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 103266 103266 'Tmem263' mRNA 829.1 879.22 942.63 11.88 12.4 14.33 16.22 14.5 15.07 12.87 15.26333333 1302.75 1137.43 1171.93 883.65 1204.036667 2.31E-05 0.430245198 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 103268 103268 'Cep57l1' mRNA 141 145 120.98 3.33 3.49 3.17 4.23 3.19 3.95 3.33 3.79 200 151 186 135.66 179 0.073450633 0.392673164 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding 103284 103284 'Zc3h10' mRNA 492 511 405 13.09 13.06 11.47 11.99 10.24 9.99 12.54 10.74 521 433 432 469.3333333 462 0.863090843 -0.032174343 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010608///posttranscriptional regulation of gene expression+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA" 103406 103406 'Zfr2' mRNA 1210 1102 1064 19.75 17.7 18.42 4.47 4.4 4.58 18.62333333 4.483333333 315 303 313 1125.333333 310.3333333 2.67E-73 -1.869596481 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008270///zinc ion binding GO:0008150///biological_process 103425 103425 'Ncln' mRNA 1658 1788 1616 30.96 32.79 32.25 38.21 36.95 37.28 32 37.48 2359 2232 2212 1687.333333 2267.666667 2.21E-09 0.415208841 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0008235///metalloexopeptidase activity+++GO:0043022///ribosome binding GO:0006508///proteolysis+++GO:0009966///regulation of signal transduction+++GO:0043254///regulation of protein complex assembly+++GO:0050821///protein stabilization+++GO:0061635///regulation of protein complex stability 103466 103466 'Nt5dc3' mRNA 667.73 668.37 509.16 6.09 5.97 4.91 2.71 2.49 2.77 5.656666667 2.656666667 339.97 304.96 338.8 615.0866667 327.91 7.90E-13 -0.91772393 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043235///receptor complex GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 103468 103468 'Nup107' mRNA 315 325 326 5.6 5.68 6.14 7.21 5.51 5.73 5.806666667 6.15 467 349 360 322 392 0.100132612 0.268411612 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031080///nuclear pore outer ring+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery" GO:0017056///structural constituent of nuclear pore "GO:0000973///posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0008585///female gonad development+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0072006///nephron development" 103511 103511 'Calhm5' mRNA 55 68 95 1.78 2.16 3.26 6.46 5.99 8.42 2.4 6.956666667 230 208 290 72.66666667 242.6666667 2.84E-12 1.719104112 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005261///cation channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 103534 103534 'Mgat4b' mRNA 485 454 415 11.15 10.28 10.12 10.4 12.61 12.76 10.51666667 11.92333333 520 616 618 451.3333333 584.6666667 0.005477181 0.36513842 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008454///alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation 103537 103537 'Mbtd1' mRNA 316 363 307 3.28 3.63 3.21 3.08 2.82 3.03 3.373333333 2.976666667 340 306 325 328.6666667 323.6666667 0.863090843 -0.032710508 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048706///embryonic skeletal system development" 103551 103551 'Epop' mRNA 0 4 0 0 0.09 0 0.27 0.11 0.22 0.03 0.2 13 5 10 1.333333333 9.333333333 0.047240296 2.813622876 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035098///ESC/E(Z) complex+++GO:0070449///elongin complex GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0048663///neuron fate commitment+++GO:0048863///stem cell differentiation 103554 103554 'Psme4' mRNA 669.77 716.87 659.65 5.57 5.91 5.93 7.09 6.41 6.56 5.803333333 6.686666667 979.73 869.69 868.44 682.0966667 905.9533333 5.91E-05 0.397933379 03050///Proteasome GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:1990111///spermatoproteasome complex GO:0016504///peptidase activator activity+++GO:0070577///lysine-acetylated histone binding+++GO:0070628///proteasome binding "GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0010952///positive regulation of peptidase activity+++GO:0030154///cell differentiation+++GO:0035093///spermatogenesis, exchange of chromosomal proteins" 103573 103573 'Xpo1' mRNA 1630 1608 1033 17.69 17.14 11.88 12.36 14.9 15.21 15.57 14.15666667 1313 1547 1565 1423.666667 1475 0.773550786 0.050766237 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++04013///MAPK signaling pathway - fly+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005642///annulate lamellae+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0005049///nuclear export signal receptor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding GO:0000054///ribosomal subunit export from nucleus+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034504///protein localization to nucleus+++GO:0042176///regulation of protein catabolic process+++GO:0042254///ribosome biogenesis+++GO:0042493///response to drug+++GO:0046825///regulation of protein export from nucleus+++GO:0051028///mRNA transport 103583 103583 'Fbxw11' mRNA 2327 2530 1542 29.61 31.5 20.74 16.18 18.07 17.72 27.28333333 17.32333333 1462 1603 1555 2133 1540 1.17E-04 -0.470494958 04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04390///Hippo signaling pathway+++04624///Toll and Imd signaling pathway+++04710///Circadian rhythm+++05131///Shigellosis+++05170///Human immunodeficiency virus 1 infection GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0005881///cytoplasmic microtubule+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:1904115///axon cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity+++GO:0051010///microtubule plus-end binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070840///dynein complex binding "GO:0000132///establishment of mitotic spindle orientation+++GO:0000209///protein polyubiquitination+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007097///nuclear migration+++GO:0007281///germ cell development+++GO:0008090///retrograde axonal transport+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0031023///microtubule organizing center organization+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031648///protein destabilization+++GO:0042752///regulation of circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045862///positive regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0047496///vesicle transport along microtubule+++GO:0048511///rhythmic process+++GO:0048854///brain morphogenesis+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:2000574///regulation of microtubule motor activity" 103611158 103611158 'Gm38666' mRNA 16.22 21.3 2.81 0.19 0.24 0.03 0 0 0 0.153333333 0 0 0 0 13.44333333 0 2.04E-04 -6.12309572 103611159 103611159 'Gm38667' mRNA 2.3 16.36 11.53 0.03 0.19 0.14 0 0.05 0 0.12 0.016666667 0 4.96 0 10.06333333 1.653333333 0.053088781 -2.856937742 GO:0016020///membrane+++GO:0016021///integral component of membrane 103655 103655 'Sec14l4' mRNA 3 7 8 0.06 0.13 0.16 0.05 0.08 0.17 0.116666667 0.1 3 5 11 6 6.333333333 0.966961 0.062003632 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008289///lipid binding 103677 103677 'Smg6' mRNA 879.85 848.91 860.72 8.08 7.63 8.39 6.18 6.22 5.88 8.033333333 6.093333333 778.25 765.87 717.43 863.16 753.85 0.047835555 -0.207601072 03015///mRNA surveillance pathway "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex" GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0042162///telomeric DNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding+++GO:0070034///telomerase RNA binding+++GO:0070182///DNA polymerase binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0032204///regulation of telomere maintenance+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1904354///negative regulation of telomere capping" 103694 103694 'Tmed4' mRNA 4371 4369 4370 157.11 154.84 166.64 104.64 108.41 101.62 159.53 104.89 3345 3382 3143 4370 3290 9.24E-11 -0.422140733 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport 103710 103710 'Slc35e4' mRNA 915 1087 926 16.41 19.18 17.61 18.34 18.24 18.86 17.73333333 18.48 1177 1143 1172 976 1164 0.010843997 0.243810606 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity GO:0055085///transmembrane transport 103711 103711 'Pnpo' mRNA 872 942 784 24.34 25.9 23.21 21.8 22.55 21.72 24.48333333 22.02333333 898 907 866 866 890.3333333 0.816954141 0.031005457 00750///Vitamin B6 metabolism+++01240///Biosynthesis of cofactors "GO:0004733///pyridoxamine-phosphate oxidase activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016638///oxidoreductase activity, acting on the CH-NH2 group of donors+++GO:0030170///pyridoxal phosphate binding+++GO:0042803///protein homodimerization activity" GO:0008615///pyridoxine biosynthetic process+++GO:0042823///pyridoxal phosphate biosynthetic process 103712 103712 '6330403K07Rik' mRNA 198 193 169 7.25 6.97 6.57 10.49 11.7 10.91 6.93 11.03333333 329 358 331 186.6666667 339.3333333 4.95E-08 0.8534199 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 103724 103724 'Tbc1d10a' mRNA 1223 1466 1347 36.58 43.21 42.74 30.86 32.41 33.07 40.84333333 32.11333333 1186 1216 1230 1345.333333 1210.666667 0.106453265 -0.163815605 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0030165///PDZ domain binding "GO:0006886///intracellular protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045862///positive regulation of proteolysis+++GO:0090630///activation of GTPase activity+++GO:0097202///activation of cysteine-type endopeptidase activity" 103733 103733 'Tubg1' mRNA 1314.47 1364.98 1288.4 46.52 47.76 48.46 42.95 42.23 41.01 47.58 42.06333333 1392.83 1336.07 1290.05 1322.616667 1339.65 0.9500099 0.006959546 05165///Human papillomavirus infection GO:0000242///pericentriolar material+++GO:0000794///condensed nuclear chromosome+++GO:0000922///spindle pole+++GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005827///polar microtubule+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0031252///cell leading edge+++GO:0036064///ciliary basal body+++GO:0045177///apical part of cell+++GO:0055037///recycling endosome+++GO:0097730///non-motile cilium+++GO:1990498///mitotic spindle microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0000212///meiotic spindle organization+++GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0007020///microtubule nucleation+++GO:0007052///mitotic spindle organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0031122///cytoplasmic microtubule organization 103737 103737 'Pex12' mRNA 578.33 643 610.39 7.36 7.91 8.68 6.33 6.24 6.37 7.983333333 6.313333333 534 481 506.02 610.5733333 507.0066667 0.019058174 -0.280442892 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990429///peroxisomal importomer complex GO:0004842///ubiquitin-protein transferase activity+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006513///protein monoubiquitination+++GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix 103742 103742 'Mien1' mRNA 1619 1763 1587 151.23 162.71 157.41 163.65 180.35 168.63 157.1166667 170.8766667 2032 2165 2007 1656.333333 2068 6.58E-05 0.310051019 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0034451///centriolar satellite GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0010269///response to selenium ion+++GO:0030335///positive regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0051491///positive regulation of filopodium assembly 103743 103743 'Tmem98' mRNA 637 613 606 26.26 24.93 26.51 75.71 75.24 78.52 25.9 76.49 2109 2045 2116 618.6666667 2090 1.71E-107 1.744520027 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome GO:0005515///protein binding GO:0010955///negative regulation of protein processing+++GO:0031642///negative regulation of myelination+++GO:0045063///T-helper 1 cell differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:1900181///negative regulation of protein localization to nucleus 103765 103765 'Tmem17' mRNA 257 285 246 11.25 12.31 11.42 5.79 5.35 6.26 11.66 5.8 152 137 159 262.6666667 149.3333333 2.50E-06 -0.825213222 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 103768 103768 'Tubg2' mRNA 330.53 369.02 369.6 10.69 11.79 12.71 4.95 4.63 4.58 11.73 4.72 175.17 159.93 156.95 356.3833333 164.0166667 1.22E-12 -1.138170904 05165///Human papillomavirus infection GO:0000242///pericentriolar material+++GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000070///mitotic sister chromatid segregation+++GO:0000212///meiotic spindle organization+++GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0007020///microtubule nucleation+++GO:0007052///mitotic spindle organization+++GO:0031122///cytoplasmic microtubule organization 103775 103775 'Slc25a41' mRNA 11 10 16 0.55 0.49 0.85 0.17 0.09 0.04 0.63 0.1 4 2 1 12.33333333 2.333333333 0.021138385 -2.430259347 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity GO:0015866///ADP transport+++GO:0015867///ATP transport+++GO:0055085///transmembrane transport+++GO:0140021///mitochondrial ADP transmembrane transport+++GO:1990544///mitochondrial ATP transmembrane transport 103784 103784 'Wdr92' mRNA 537.82 571.79 508.02 8.53 8.93 8.55 10.74 10.33 10.72 8.67 10.59666667 779 731.39 752.47 539.21 754.2866667 4.22E-06 0.474365286 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0043130///ubiquitin binding GO:0006915///apoptotic process+++GO:0070286///axonemal dynein complex assembly 103806 103806 'Maml1' mRNA 261 277 224 2.47 2.52 2.24 2.51 2.31 2.33 2.41 2.383333333 304 273 272 254 283 0.427889871 0.146578859 04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0003713///transcription coactivator activity+++GO:0019901///protein kinase binding+++GO:0042605///peptide antigen binding GO:0006468///protein phosphorylation+++GO:0007219///Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0010831///positive regulation of myotube differentiation+++GO:0045445///myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0060928///atrioventricular node cell development 103836 103836 'Zfp692' mRNA 819 772 800 21.76 20.19 22.28 12.37 12.34 11.55 21.41 12.08666667 521 517 476 797 504.6666667 4.11E-10 -0.67217743 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043035///chromatin insulator sequence binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006111///regulation of gluconeogenesis+++GO:0006357///regulation of transcription by RNA polymerase II 103841 103841 'Cuedc1' mRNA 1429 1456 1191 24.89 24.8 21.87 11.04 11.99 12.08 23.85333333 11.70333333 733 777 773 1358.666667 761 1.43E-20 -0.843756127 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0043130///ubiquitin binding GO:0008150///biological_process 103844 103844 'Inca1' mRNA 89 126 90 5.16 7.43 5.1 3.46 3.8 3.78 5.896666667 3.68 68 78 74 101.6666667 73.33333333 0.107525392 -0.477841204 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0030332///cyclin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:2001235///positive regulation of apoptotic signaling pathway 103850 103850 'Nt5m' mRNA 589.99 615.97 428.99 27.31 28.14 21.07 18.38 21.74 18.97 25.50666667 19.69666667 455.99 526 454.99 544.9833333 478.9933333 0.230097919 -0.189298918 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0009117///nucleotide metabolic process+++GO:0009223///pyrimidine deoxyribonucleotide catabolic process+++GO:0009264///deoxyribonucleotide catabolic process+++GO:0016311///dephosphorylation+++GO:0046079///dUMP catabolic process 103889 103889 'Hoxb2' mRNA 5 6 3 0.27 0.31 0.17 0.09 0.09 0.29 0.25 0.156666667 2 2 6 4.666666667 3.333333333 0.769181771 -0.483819635 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002011///morphogenesis of an epithelial sheet+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0021569///rhombomere 3 development+++GO:0021570///rhombomere 4 development+++GO:0021612///facial nerve structural organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048857///neural nucleus development" 103963 103963 'Rpn1' mRNA 6418 6374 6310 95.61 93.41 99.71 112.8 117.7 109.33 96.24333333 113.2766667 8714 8882 8180 6367.333333 8592 1.59E-12 0.42008669 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042470///melanosome GO:0005515///protein binding GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine 103967 103967 'Dnm3' mRNA 617.02 523.92 483.77 5.94 5.41 5.32 1.3 1.7 1.57 5.556666667 1.523333333 189.84 195.71 186.66 541.57 190.7366667 6.56E-27 -1.518761689 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05100///Bacterial invasion of epithelial cells GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0043083///synaptic cleft+++GO:0043197///dendritic spine+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0061828///apical tubulobulbar complex+++GO:0061829///basal tubulobulbar complex+++GO:0098793///presynapse+++GO:0098844///postsynaptic endocytic zone membrane+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0031798///type 1 metabotropic glutamate receptor binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0099186///structural constituent of postsynapse GO:0000266///mitochondrial fission+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0006897///endocytosis+++GO:0007416///synapse assembly+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0031623///receptor internalization+++GO:0046847///filopodium assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0050803///regulation of synapse structure or activity+++GO:0051491///positive regulation of filopodium assembly+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0061025///membrane fusion+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:0099173///postsynapse organization+++GO:1903423///positive regulation of synaptic vesicle recycling 103968 103968 'Plin1' mRNA 0 2 0 0 0.06 0 0.03 0 0 0.02 0.01 1 0 0 0.666666667 0.333333333 0.863090843 -0.864667557 03320///PPAR signaling pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++04923///Regulation of lipolysis in adipocytes GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol GO:0005515///protein binding GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0070417///cellular response to cold 103978 103978 'Gpc5' mRNA 808 845 697 11.31 10.96 10.39 1.13 1.07 1.04 10.88666667 1.08 89 80 71 783.3333333 80 3.41E-110 -3.300777893 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0009966///regulation of signal transduction+++GO:0016477///cell migration+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1905475///regulation of protein localization to membrane 103988 103988 'Gck' mRNA 234 231 252 5.19 4.84 5.64 0.79 0.74 0.62 5.223333333 0.716666667 45 36 34 239 38.33333333 1.94E-29 -2.656187274 "00010///Glycolysis / Gluconeogenesis+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++00524///Neomycin, kanamycin and gentamicin biosynthesis+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars+++04910///Insulin signaling pathway+++04911///Insulin secretion+++04917///Prolactin signaling pathway+++04922///Glucagon signaling pathway+++04930///Type II diabetes mellitus+++04950///Maturity onset diabetes of the young+++05230///Central carbon metabolism in cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0045180///basal cortex "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004340///glucokinase activity+++GO:0004370///glycerol kinase activity+++GO:0004396///hexokinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008865///fructokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019158///mannokinase activity+++GO:0019903///protein phosphatase binding+++GO:0042393///histone binding+++GO:0043531///ADP binding" "GO:0001678///cellular glucose homeostasis+++GO:0005975///carbohydrate metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006013///mannose metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0006641///triglyceride metabolic process+++GO:0006739///NADP metabolic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019318///hexose metabolic process+++GO:0019563///glycerol catabolic process+++GO:0019932///second-messenger-mediated signaling+++GO:0032024///positive regulation of insulin secretion+++GO:0032811///negative regulation of epinephrine secretion+++GO:0032869///cellular response to insulin stimulus+++GO:0042149///cellular response to glucose starvation+++GO:0042327///positive regulation of phosphorylation+++GO:0042593///glucose homeostasis+++GO:0043266///regulation of potassium ion transport+++GO:0044320///cellular response to leptin stimulus+++GO:0045471///response to ethanol+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045821///positive regulation of glycolytic process+++GO:0046167///glycerol-3-phosphate biosynthetic process+++GO:0046835///carbohydrate phosphorylation+++GO:0050796///regulation of insulin secretion+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0051594///detection of glucose+++GO:0055088///lipid homeostasis+++GO:0070509///calcium ion import" 104001 104001 'Rtn1' mRNA 3432 3510 2227 85.02 84.86 69.09 23.45 29.56 28.9 79.65666667 27.30333333 959 1255 1179 3056.333333 1131 1.69E-11 -1.432985658 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:1902430///negative regulation of amyloid-beta formation 104009 104009 'Qsox1' mRNA 1300 1276 1109 25.12 23.81 21.59 57.43 54.39 62.01 23.50666667 57.94333333 3453 3243 3598 1228.333333 3431.333333 3.26E-97 1.472501329 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0070062///extracellular exosome GO:0003756///protein disulfide isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0016972///thiol oxidase activity+++GO:0071949///FAD binding GO:0006457///protein folding+++GO:0016242///negative regulation of macroautophagy+++GO:0085029///extracellular matrix assembly 104010 104010 'Cdh22' mRNA 11 11 13 0.17 0.16 0.21 0.05 0.01 0.01 0.18 0.023333333 4 1 1 11.66666667 2 0.020391806 -2.568768501 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 104015 104015 'Synj1' mRNA 1030.93 1073.98 846.69 7.7 7.97 6.7 6.02 6.5 6.32 7.456666667 6.28 939.14 970.37 947.34 983.8666667 952.2833333 0.673646829 -0.053471976 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0012506///vesicle membrane+++GO:0030117///membrane coat+++GO:0030118///clathrin coat+++GO:0030132///clathrin coat of coated pit+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0034595///phosphatidylinositol phosphate 5-phosphatase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:1990175///EH domain binding" GO:0006836///neurotransmitter transport+++GO:0006897///endocytosis+++GO:0007420///brain development+++GO:0007612///learning+++GO:0014015///positive regulation of gliogenesis+++GO:0016082///synaptic vesicle priming+++GO:0016191///synaptic vesicle uncoating+++GO:0032526///response to retinoic acid+++GO:0034097///response to cytokine+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048489///synaptic vesicle transport+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:1904980///positive regulation of endosome organization 104027 104027 'Synpo' mRNA 1301 1220 667 13.67 12.71 7.41 11.1 13.92 13.63 11.26333333 12.88333333 1251 1525 1484 1062.666667 1420 0.194939672 0.422476484 04530///Tight junction GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0071944///cell periphery+++GO:0097444///spine apparatus+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding GO:0008542///visual learning+++GO:0030865///cortical cytoskeleton organization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0051492///regulation of stress fiber assembly+++GO:0098886///modification of dendritic spine+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:0099588///positive regulation of postsynaptic cytosolic calcium concentration+++GO:1905355///spine apparatus assembly 104069 104069 'Sncb' mRNA 2 3 1 0.09 0.13 0.05 0.04 0 0 0.09 0.013333333 1 0 0 2 0.333333333 0.381909345 -2.474813369 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016234///inclusion body+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0099523///presynaptic cytosol GO:0005509///calcium ion binding+++GO:0043014///alpha-tubulin binding+++GO:0046914///transition metal ion binding+++GO:0048487///beta-tubulin binding+++GO:1903136///cuprous ion binding GO:0007268///chemical synaptic transmission+++GO:0042417///dopamine metabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0050808///synapse organization+++GO:1901214///regulation of neuron death 104079 104079 'Nxph3' mRNA 8 18 7 0.22 0.4 0.2 0.4 0.37 0.36 0.273333333 0.376666667 17 16 15 11 16 0.520221545 0.540682618 GO:0005576///extracellular region GO:0005102///signaling receptor binding 104080 104080 'Nxph4' mRNA 13 5 6 0.45 0.17 0.22 1.33 0.81 1.37 0.28 1.17 44 26 44 8 38 1.69E-04 2.2361561 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0005102///signaling receptor binding GO:0008150///biological_process 104082 104082 'Wdr7' mRNA 927 973 927 6.99 7.2 7.4 4.63 4.54 4.66 7.196666667 4.61 708 679 689 942.3333333 692 1.33E-06 -0.457476455 04142///Lysosome GO:0005737///cytoplasm+++GO:0008021///synaptic vesicle GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 104086 104086 'Cyp27a1' mRNA 402 404 369 11.51 11.43 11.24 21.19 20.05 19.85 11.39333333 20.36333333 850 789 774 391.6666667 804.3333333 2.21E-22 1.027013222 00120///Primary bile acid biosynthesis+++03320///PPAR signaling pathway+++04979///Cholesterol metabolism GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008123///cholesterol 7-alpha-monooxygenase activity+++GO:0008386///cholesterol monooxygenase (side-chain-cleaving) activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0030544///Hsp70 protein binding+++GO:0031073///cholesterol 26-hydroxylase activity+++GO:0046872///metal ion binding+++GO:0047748///cholestanetetraol 26-dehydrogenase activity+++GO:0047749///cholestanetriol 26-monooxygenase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006707///cholesterol catabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0036378///calcitriol biosynthetic process from calciol 104099 104099 'Itga9' mRNA 148 141 103 1.31 1.21 1.05 1.3 1.09 1.07 1.19 1.153333333 171 138 136 130.6666667 148.3333333 0.521530405 0.175135435 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0008305///integrin complex+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034679///integrin alpha9-beta1 complex+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex GO:0005518///collagen binding+++GO:0043236///laminin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0042060///wound healing+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0048858///cell projection morphogenesis 104110 104110 'Adcy4' mRNA 93 56 69 1.56 0.87 1.15 3.07 3.08 3.03 1.193333333 3.06 212 211 203 72.66666667 208.6666667 6.03E-11 1.50988307 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005080///protein kinase C binding+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0006171///cAMP biosynthetic process+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction 104111 104111 'Adcy3' mRNA 126.11 125.05 142.61 1.5 1.45 1.83 2.67 2.27 1.99 1.593333333 2.31 253.65 216.28 183.46 131.2566667 217.7966667 6.15E-04 0.713736561 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04740///Olfactory transduction+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05110///Vibrio cholerae infection+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0046872///metal ion binding GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007338///single fertilization+++GO:0007340///acrosome reaction+++GO:0007608///sensory perception of smell+++GO:0008355///olfactory learning+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0030317///flagellated sperm motility+++GO:0035556///intracellular signal transduction+++GO:0050896///response to stimulus+++GO:1904322///cellular response to forskolin 104112 104112 'Acly' mRNA 4296 4300 4566 52.1 51.34 58.7 43.14 40.61 40.66 54.04666667 41.47 4089 3767.01 3741 4387.333333 3865.67 0.008143139 -0.197641573 00020///Citrate cycle (TCA cycle) GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003878///ATP citrate synthase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0046912///transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer" GO:0006084///acetyl-CoA metabolic process+++GO:0006085///acetyl-CoA biosynthetic process+++GO:0006101///citrate metabolic process+++GO:0006107///oxaloacetate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0008610///lipid biosynthetic process 104130 104130 'Ndufb11' mRNA 2958.76 2876.56 3009.61 235.76 226.57 257.37 208.42 248.72 224.66 239.9 227.2666667 2985.76 3453.9 3093.75 2948.31 3177.803333 0.321112604 0.095974728 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 104156 104156 'Etv5' mRNA 538 544 501 7.6 7.58 7.52 13.4 12.38 11.57 7.566666667 12.45 1090 983 913 527.6666667 995.3333333 3.06E-19 0.903767164 05202///Transcriptional misregulation in cancer+++05215///Prostate cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0045202///synapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007274///neuromuscular synaptic transmission+++GO:0007626///locomotory behavior+++GO:0030154///cell differentiation+++GO:0034599///cellular response to oxidative stress+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048133///male germ-line stem cell asymmetric division+++GO:0050807///regulation of synapse organization+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060762///regulation of branching involved in mammary gland duct morphogenesis+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering" 104158 104158 'Ces1d' mRNA 6484 6679 6519 188.13 190.93 200.65 63.17 63.57 60.86 193.2366667 62.53333333 2503 2459 2334 6560.666667 2432 1.56E-127 -1.444252758 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0030339///fatty-acyl-ethyl-ester synthase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0080030///methyl indole-3-acetate esterase activity" GO:0006629///lipid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0009636///response to toxic substance+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0016042///lipid catabolic process+++GO:0019626///short-chain fatty acid catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0042572///retinol metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0046464///acylglycerol catabolic process+++GO:0051791///medium-chain fatty acid metabolic process+++GO:0060086///circadian temperature homeostasis+++GO:0061411///positive regulation of transcription from RNA polymerase II promoter in response to cold+++GO:0061725///cytosolic lipolysis+++GO:0070417///cellular response to cold+++GO:0070857///regulation of bile acid biosynthetic process+++GO:0071397///cellular response to cholesterol+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090205///positive regulation of cholesterol metabolic process+++GO:0106106///cold-induced thermogenesis+++GO:0120188///regulation of bile acid secretion 104174 104174 'Gldc' mRNA 2 1 2 0.03 0.01 0.03 0.24 0.22 0.12 0.023333333 0.193333333 19 17 9 1.666666667 15 0.002938562 3.152331168 "00260///Glycine, serine and threonine metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005960///glycine cleavage complex GO:0003824///catalytic activity+++GO:0004375///glycine dehydrogenase (decarboxylating) activity+++GO:0016491///oxidoreductase activity+++GO:0016594///glycine binding+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0030170///pyridoxal phosphate binding+++GO:0042803///protein homodimerization activity+++GO:0070280///pyridoxal binding GO:0006520///cellular amino acid metabolic process+++GO:0006544///glycine metabolic process+++GO:0006546///glycine catabolic process+++GO:0019464///glycine decarboxylation via glycine cleavage system+++GO:0036255///response to methylamine+++GO:0065003///protein-containing complex assembly+++GO:1903442///response to lipoic acid+++GO:1990830///cellular response to leukemia inhibitory factor 104175 104175 'Sbk1' mRNA 264 279 225 3.62 3.8 3.18 1.83 1.81 2.15 3.533333333 1.93 151 147 172 256 156.6666667 6.41E-05 -0.716589895 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation 104183 104183 'Chil4' mRNA 0 2.04 0 0 0.08 0 0.04 0.04 0 0.026666667 0.026666667 1 1 0 0.68 0.666666667 0.998591786 0.024844852 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0008061///chitin binding+++GO:0019900///kinase binding GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0006954///inflammatory response+++GO:0032722///positive regulation of chemokine production 104184 104184 'Blmh' mRNA 1160 1139 1130 27.59 26.67 28.51 33.83 29.46 32 27.59 31.76333333 1636 1391 1498 1143 1508.333333 6.05E-06 0.386680908 GO:0005737///cytoplasm GO:0004177///aminopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0009410///response to xenobiotic stimulus+++GO:0009636///response to toxic substance+++GO:0042493///response to drug+++GO:0043418///homocysteine catabolic process 104215 104215 'Rhoq' mRNA 771.36 799.31 693.07 10.09 10.28 9.61 8.04 6.93 7.09 9.993333333 7.353333333 707.69 595.95 604.71 754.58 636.1166667 0.019874864 -0.258787524 04910///Insulin signaling pathway GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0005525///GTP binding+++GO:0032427///GBD domain binding GO:0006897///endocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032869///cellular response to insulin stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046039///GTP metabolic process+++GO:0046325///negative regulation of glucose import+++GO:0046326///positive regulation of glucose import+++GO:0051491///positive regulation of filopodium assembly+++GO:1903077///negative regulation of protein localization to plasma membrane 104245 104245 'Slc6a5' mRNA 0 1 4 0 0.01 0.03 0 0 0 0.013333333 0 0 0 0 1.666666667 0 0.363515866 -3.240550971 04721///Synaptic vesicle cycle GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031045///dense core granule+++GO:0098690///glycinergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0015187///glycine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015375///glycine:sodium symporter activity+++GO:0046872///metal ion binding "GO:0001504///neurotransmitter uptake+++GO:0006836///neurotransmitter transport+++GO:0015816///glycine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0060012///synaptic transmission, glycinergic+++GO:0098810///neurotransmitter reuptake+++GO:1903804///glycine import across plasma membrane" 104248 104248 'Cabin1' mRNA 1513 1607 1476 13.63 14.33 14.89 9.69 9.99 8.72 14.28333333 9.466666667 1229 1164 1099 1532 1164 4.33E-07 -0.407916239 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome GO:0004864///protein phosphatase inhibitor activity+++GO:0019904///protein domain specific binding+++GO:0030346///protein phosphatase 2B binding+++GO:0031491///nucleosome binding GO:0006336///DNA replication-independent nucleosome assembly+++GO:0007165///signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0060548///negative regulation of cell death 104252 104252 'Cdc42ep2' mRNA 531 580 608 21.06 22.69 25.59 16.27 14.37 16.14 23.11333333 15.59333333 471 406 452 573 443 0.00304952 -0.386549362 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0045335///phagocytic vesicle GO:0001515///opioid peptide activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0050790///regulation of catalytic activity+++GO:0071346///cellular response to interferon-gamma 104263 104263 'Kdm3a' mRNA 967 1098 1119 11.43 12.77 14.17 6.6 8.18 6.32 12.79 7.033333333 650 754 609 1061.333333 671 9.08E-09 -0.674555115 04714///Thermogenesis GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051213///dioxygenase activity "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007290///spermatid nucleus elongation+++GO:0009755///hormone-mediated signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030521///androgen receptor signaling pathway+++GO:0032259///methylation+++GO:0033169///histone H3-K9 demethylation+++GO:0036123///histone H3-K9 dimethylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046293///formaldehyde biosynthetic process+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000036///regulation of stem cell population maintenance+++GO:2000736///regulation of stem cell differentiation" 104271 104271 'Tex15' mRNA 148 173 161 0.82 0.96 0.94 0.88 0.8 0.86 0.906666667 0.846666667 183 162 174 160.6666667 173 0.720642128 0.093936897 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006306///DNA methylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0010529///negative regulation of transposition+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0030154///cell differentiation+++GO:0030539///male genitalia development+++GO:0031047///gene silencing by RNA+++GO:0032880///regulation of protein localization+++GO:0034502///protein localization to chromosome+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051321///meiotic cell cycle+++GO:1990511///piRNA biosynthetic process 104303 104303 'Arl1' mRNA 4572 4697 4646 129.72 131.29 139.84 132.97 134.77 136.29 133.6166667 134.6766667 5388 5331 5345 4638.333333 5354.666667 0.001684726 0.194597226 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008047///enzyme activator activity+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding "GO:0006886///intracellular protein transport+++GO:0007030///Golgi organization+++GO:0009404///toxin metabolic process+++GO:0016192///vesicle-mediated transport+++GO:0031584///activation of phospholipase D activity+++GO:0034067///protein localization to Golgi apparatus+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport" 104318 104318 'Csnk1d' mRNA 2621.07 2804 2028 38.13 40.09 31.27 32.29 33.13 31.28 36.49666667 32.23333333 2559 2560 2400 2484.356667 2506.333333 0.953298785 0.007217021 04340///Hedgehog signaling pathway+++04390///Hippo signaling pathway+++04540///Gap junction+++04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0036064///ciliary basal body+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0050321///tau-protein kinase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007020///microtubule nucleation+++GO:0007030///Golgi organization+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032922///circadian regulation of gene expression+++GO:0034067///protein localization to Golgi apparatus+++GO:0042752///regulation of circadian rhythm+++GO:0048511///rhythmic process+++GO:0051225///spindle assembly+++GO:0061512///protein localization to cilium+++GO:0071539///protein localization to centrosome+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation+++GO:1905515///non-motile cilium assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway 104346 104346 'Gas8' mRNA 891.97 886 910 21.73 21.7 23.67 14.51 14.73 13.63 22.36666667 14.29 626 618 573 895.99 605.6666667 1.59E-08 -0.577660346 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031267///small GTPase binding GO:0003351///epithelial cilium movement+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0030317///flagellated sperm motility+++GO:0034613///cellular protein localization+++GO:0035082///axoneme assembly+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048870///cell motility+++GO:0060294///cilium movement involved in cell motility+++GO:1903566///positive regulation of protein localization to cilium+++GO:1904526///regulation of microtubule binding 104348 104348 'Zfp120' mRNA 393 402 397 5.19 5.21 5.56 5.59 5.04 5.11 5.32 5.246666667 487 429 431 397.3333333 449 0.259570134 0.163071697 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 104349 104349 'Zfp119a' mRNA 280.58 284.49 272.84 6.57 6.54 7.01 3.85 3.72 3.35 6.706666667 3.64 188.99 184.52 161.75 279.3033333 178.42 8.70E-05 -0.661297551 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 104360 104360 'Isl2' mRNA 82 107 102 1.85 2.43 2.59 1.02 0.76 1.47 2.29 1.083333333 46 43 65 97 51.33333333 0.003052558 -0.931147316 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0021524///visceral motor neuron differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0045665///negative regulation of neuron differentiation+++GO:0048663///neuron fate commitment+++GO:0048665///neuron fate specification" 104362 104362 'Meig1' mRNA 296 292 290 35.59 34.5 37.19 6.33 7.07 4.36 35.76 5.92 60 61 39 292.6666667 53.33333333 8.54E-31 -2.468886204 GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0005515///protein binding GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0030154///cell differentiation+++GO:0034613///cellular protein localization+++GO:0051321///meiotic cell cycle+++GO:1905198///manchette assembly 104382 104382 'Barhl2' mRNA 1 1 1 0.02 0.02 0.03 0 0 0 0.023333333 0 0 0 0 1 0 0.568344116 -2.455252046 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001709///cell fate determination+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030182///neuron differentiation+++GO:0030516///regulation of axon extension+++GO:0045165///cell fate commitment+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 104383 104383 'Rcor2' mRNA 28 32 21 0.69 0.78 0.55 0.6 0.48 0.33 0.673333333 0.47 28 22 15 27 21.66666667 0.614342337 -0.325270815 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:1990391///DNA repair complex GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression+++GO:0016575///histone deacetylation+++GO:0030218///erythrocyte differentiation+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation" 104394 104394 'E2f4' mRNA 344 353 229 9.83 9.94 6.94 11.63 11.1 12.53 8.903333333 11.75333333 468 436 488 308.6666667 464 1.78E-04 0.583866521 04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0002064///epithelial cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006884///cell volume homeostasis+++GO:0007049///cell cycle+++GO:0008015///blood circulation+++GO:0008361///regulation of cell size+++GO:0009887///animal organ morphogenesis+++GO:0030030///cell projection organization+++GO:0042127///regulation of cell proliferation+++GO:0044458///motile cilium assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0060271///cilium assembly+++GO:0098534///centriole assembly+++GO:1903251///multi-ciliated epithelial cell differentiation" 104401 104401 'Pcnx3' mRNA 933.48 971.51 830.92 6.94 7.11 6.6 4.95 4.58 4.99 6.883333333 4.84 765.47 687.96 746.36 911.97 733.2633333 8.81E-04 -0.324875358 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 104416 104416 'Bap1' mRNA 1632 1835 1707 26.1 28.88 28.96 22.95 20.6 22.14 27.98 21.89666667 1651 1448 1543 1724.666667 1547.333333 0.052402072 -0.169396545 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035517///PR-DUB complex GO:0003682///chromatin binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0001558///regulation of cell growth+++GO:0006325///chromatin organization+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010035///response to inorganic substance+++GO:0016579///protein deubiquitination+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050727///regulation of inflammatory response+++GO:0051726///regulation of cell cycle+++GO:0061519///macrophage homeostasis+++GO:0071108///protein K48-linked deubiquitination+++GO:1900015///regulation of cytokine production involved in inflammatory response" 104418 104418 'Dgkz' mRNA 475.93 427.32 386.82 6.12 5.25 5.24 22.55 20.84 22.56 5.536666667 21.98333333 1800 1607.37 1719.32 430.0233333 1708.896667 1.11E-103 1.982201782 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0001727///lipid kinase activity+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046834///lipid phosphorylation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0090216///positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0099562///maintenance of postsynaptic density structure" 104443 104443 'Npffr2' mRNA 9 0 1 0.3 0 0.04 0 0 0 0.113333333 0 0 0 0 3.333333333 0 0.124271858 -4.175081652 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0031628///opioid receptor binding+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0045761///regulation of adenylate cyclase activity+++GO:2000479///regulation of cAMP-dependent protein kinase activity 104444 104444 'Rexo2' mRNA 956 927 974 56.72 54.64 61.46 106.5 121.47 115.61 57.60666667 114.5266667 2061 2292 2162 952.3333333 2171.666667 2.11E-42 1.17711244 03008///Ribosome biogenesis in eukaryotes GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005925///focal adhesion "GO:0000175///3'-5'-exoribonuclease activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding" "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001836///release of cytochrome c from mitochondria+++GO:0003334///keratinocyte development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010482///regulation of epidermal cell division+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0030216///keratinocyte differentiation+++GO:0030307///positive regulation of cell growth+++GO:0031424///keratinization+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043588///skin development+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0051726///regulation of cell cycle+++GO:0061436///establishment of skin barrier+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 104445 104445 'Cdc42ep1' mRNA 2131 2094 1862 46.64 45.12 43.23 44.09 47.52 46.54 44.99666667 46.05 2317 2439 2368 2029 2374.666667 0.003011818 0.217822548 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0005515///protein binding GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly 104457 104457 '0610010K14Rik' mRNA 705 734 637 57.13 59.77 54.32 78.52 83.16 74.1 57.07333333 78.59333333 1081 1114 976 692 1057 5.30E-10 0.601565936 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016589///NURF complex+++GO:0071339///MLL1 complex GO:0003677///DNA binding+++GO:0042802///identical protein binding GO:0006325///chromatin organization+++GO:0008150///biological_process 104458 104458 'Rars' mRNA 706 727 710 18.71 18.97 19.97 36.22 33.95 34.44 19.21666667 34.87 1570 1437 1446 714.3333333 1484.333333 8.15E-35 1.042400879 00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004814///arginine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0034618///arginine binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006420///arginyl-tRNA aminoacylation 104479 104479 'Ccdc117' mRNA 831 911 396 13.31 14.35 6.73 6.58 12.94 10 11.46333333 9.84 473 908 696 712.6666667 692.3333333 0.963922838 -0.029528342 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 104570 104570 'Ppp4r3b' mRNA 1768.84 1846.09 1846.56 17.23 17.81 19.6 17.77 15.76 16.97 18.21333333 16.83333333 2014.05 1758.84 1768.31 1820.496667 1847.066667 0.952328998 0.006788511 04212///Longevity regulating pathway - worm+++04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0030289///protein phosphatase 4 complex GO:0005515///protein binding GO:0006470///protein dephosphorylation+++GO:0045722///positive regulation of gluconeogenesis 104582 104582 'Rprml' mRNA 3 0 0 0.18 0 0 0 0.1 0.32 0.06 0.14 0 2 6 1 2.666666667 0.601550518 1.43450872 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 104601 104601 'Mycbpap' mRNA 1420 1577 1529 26.58 29.1 30.4 2.85 2.71 3.09 28.69333333 2.883333333 175 163 185 1508.666667 174.3333333 3.64E-171 -3.1264211 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0045202///synapse GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 104625 104625 'Cnot6' mRNA 927 926 925 8.61 8.52 9.1 8.99 6.69 8.36 8.743333333 8.013333333 1108 804 1004 926 972 0.720293678 0.054852915 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030014///CCR4-NOT complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004532///exoribonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046872///metal ion binding "GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0006417///regulation of translation+++GO:0008284///positive regulation of cell proliferation+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0031047///gene silencing by RNA+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070966///nuclear-transcribed mRNA catabolic process, no-go decay+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 104662 104662 'Tsr1' mRNA 328.75 387.1 358.19 5.29 6.13 6.12 7.97 8.94 8.51 5.846666667 8.473333333 569.83 623.98 588.91 358.0133333 594.24 1.27E-08 0.719219263 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030688///preribosome, small subunit precursor" GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0034511///U3 snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0042254///ribosome biogenesis" 104681 104681 'Slc16a6' mRNA 1359.52 1344.53 1330.62 15.78 15.08 16.71 30.49 29.51 30.82 15.85666667 30.27333333 2964.18 2784.62 2876.57 1344.89 2875.123333 1.42E-57 1.084018734 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport 104709 104709 'Pik3r6' mRNA 25 40 33 0.45 0.67 0.63 2.72 2.88 3.29 0.583333333 2.963333333 183 191 214 32.66666667 196 1.02E-22 2.574681512 04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04611///Platelet activation+++04725///Cholinergic synapse+++04921///Oxytocin signaling pathway+++05145///Toxoplasmosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005944///phosphatidylinositol 3-kinase complex, class IB+++GO:0016020///membrane" "GO:0005515///protein binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity" GO:0001525///angiogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0042269///regulation of natural killer cell mediated cytotoxicity+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045582///positive regulation of T cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0046854///phosphatidylinositol phosphorylation 104718 104718 'Ttc7b' mRNA 393 337 338 6.25 5.34 5.62 3.9 3.76 3.3 5.736666667 3.653333333 277 267 231 356 258.3333333 0.00241529 -0.474381331 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 104721 104721 'Ddx1' mRNA 2137 2206 2126 48.27 49.06 50.95 45.37 46.46 45.32 49.42666667 45.71666667 2310 2310 2234 2156.333333 2284.666667 0.383479487 0.071515704 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0071920///cleavage body+++GO:0072669///tRNA-splicing ligase complex+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008143///poly(A) binding+++GO:0016787///hydrolase activity+++GO:0033677///DNA/RNA helicase activity "GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0006302///double-strand break repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0009615///response to virus+++GO:0032508///DNA duplex unwinding+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1903608///protein localization to cytoplasmic stress granule" 104725 104725 'Sptssa' mRNA 3923 4071 3814 172.71 176.86 178.14 188.05 185.03 185.94 175.9033333 186.34 4905 4708 4691 3936 4768 3.02E-06 0.265002932 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex GO:0004758///serine C-palmitoyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008104///protein localization+++GO:0046513///ceramide biosynthetic process 104732 104732 'Tedc1' mRNA 314.01 392.01 368.17 4.51 5.5 5.78 4.43 4.5 3.99 5.263333333 4.306666667 339.08 343.62 306.47 358.0633333 329.7233333 0.461854737 -0.133134927 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0045880///positive regulation of smoothened signaling pathway 104759 104759 'Pld4' mRNA 509 535 506 14.97 15.19 15.47 140.62 145.16 141.61 15.21 142.4633333 5507 5603 5391 516.6666667 5500.333333 0 3.40119818 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004630///phospholipase D activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002376///immune system process+++GO:0006259///DNA metabolic process+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0045087///innate immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1900015///regulation of cytokine production involved in inflammatory response 104771 104771 'Jkamp' mRNA 1570 1450 1372 45.49 41.43 42.12 46.67 48.5 47.68 43.01333333 47.61666667 1852 1881 1833 1464 1855.333333 1.78E-05 0.331396719 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031625///ubiquitin protein ligase binding GO:0006986///response to unfolded protein+++GO:0030433///ubiquitin-dependent ERAD pathway 104776 104776 'Aldh6a1' mRNA 2631.03 2775.03 2710.46 41.82 43.43 45.67 27.95 26.43 25.23 43.64 26.53666667 2020.52 1867.24 1763.51 2705.506667 1883.756667 3.77E-13 -0.535843541 "00280///Valine, leucine and isoleucine degradation+++00410///beta-Alanine metabolism+++00562///Inositol phosphate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0004491///methylmalonate-semialdehyde dehydrogenase (acylating) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016790///thiolester hydrolase activity+++GO:0018478///malonate-semialdehyde dehydrogenase (acetylating) activity+++GO:0102662///malonate-semialdehyde dehydrogenase (acetylating, NAD+) activity" GO:0006210///thymine catabolic process+++GO:0006573///valine metabolic process+++GO:0006574///valine catabolic process+++GO:0019484///beta-alanine catabolic process+++GO:0019859///thymine metabolic process+++GO:0050873///brown fat cell differentiation 104799 104799 'Vipas39' mRNA 1154.03 1258.02 1188 25.13 26.97 27.46 27 27.02 27.19 26.52 27.07 1424.04 1394 1390 1200.016667 1402.68 0.013044893 0.21319039 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome GO:0044877///protein-containing complex binding GO:0006886///intracellular protein transport+++GO:0007034///vacuolar transport+++GO:0007283///spermatogenesis+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0032963///collagen metabolic process+++GO:0043687///post-translational protein modification 104806 104806 'Fancm' mRNA 225 199 209 1.46 1.31 1.51 1.45 1.22 1.49 1.426666667 1.386666667 246 202 248 211 232 0.576271142 0.123297526 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043240///Fanconi anaemia nuclear complex+++GO:0071821///FANCM-MHF complex GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0005524///ATP binding+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0043138///3'-5' DNA helicase activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0032508///DNA duplex unwinding+++GO:0036297///interstrand cross-link repair+++GO:0045003///double-strand break repair via synthesis-dependent strand annealing+++GO:0071932///replication fork reversal+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1902527///positive regulation of protein monoubiquitination 104816 104816 'Aspg' mRNA 272 281 242 5.87 6.08 5.81 55.88 51.14 50.54 5.92 52.52 2966 2612 2586 265 2721.333333 6.09E-299 3.349136435 "GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0004067///asparaginase activity+++GO:0004622///lysophospholipase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016787///hydrolase activity+++GO:0102545///phosphatidyl phospholipase B activity" GO:0006520///cellular amino acid metabolic process+++GO:0006528///asparagine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0016042///lipid catabolic process 104831 104831 'Ptpn23' mRNA 767 743 511 7.53 7.21 5.34 7.13 6.17 7.31 6.693333333 6.87 838 704 833 673.6666667 791.6666667 0.110017128 0.22754786 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016604///nuclear body+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding GO:0006470///protein dephosphorylation+++GO:0010633///negative regulation of epithelial cell migration+++GO:0015031///protein transport+++GO:0016311///dephosphorylation+++GO:0030030///cell projection organization+++GO:0032456///endocytic recycling+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0045022///early endosome to late endosome transport+++GO:0060271///cilium assembly+++GO:0061357///positive regulation of Wnt protein secretion+++GO:1903387///positive regulation of homophilic cell adhesion+++GO:1903393///positive regulation of adherens junction organization+++GO:2000643///positive regulation of early endosome to late endosome transport 104836 104836 'Cbll1' mRNA 689.14 654.08 679 8.43 7.94 8.91 7.1 7.07 7.01 8.426666667 7.06 661 651.86 642 674.0733333 651.62 0.653040635 -0.062211143 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0030155///regulation of cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:0045807///positive regulation of endocytosis+++GO:0080009///mRNA methylation+++GO:0098609///cell-cell adhesion 104859 104859 'Tecpr2' mRNA 518 461.01 432.04 3.51 3.07 3.11 2.21 2.38 2.13 3.23 2.24 376.99 393.86 351 470.35 373.95 0.011659468 -0.343043841 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0032527///protein exit from endoplasmic reticulum 104871 104871 'Spata7' mRNA 381 411 397 10.27 11.53 11.32 5.86 5.03 4.23 11.04 5.04 234 207 165 396.3333333 202 8.11E-10 -0.986140433 GO:0001750///photoreceptor outer segment+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0007601///visual perception+++GO:0045494///photoreceptor cell maintenance+++GO:0050896///response to stimulus+++GO:1903546///protein localization to photoreceptor outer segment+++GO:1903621///protein localization to photoreceptor connecting cilium 104884 104884 'Tdp1' mRNA 331 379 391 8.97 10.11 11.2 9.4 10.65 10.66 10.09333333 10.23666667 407 445 452 367 434.6666667 0.137695289 0.230959078 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0017005///3'-tyrosyl-DNA phosphodiesterase activity GO:0000012///single strand break repair+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 104885 104885 'Tmem179' mRNA 672 787 713 15.85 18.28 17.84 2.24 2.04 2.35 17.32333333 2.21 109 97 111 724 105.6666667 8.06E-84 -2.788521585 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 104886 104886 'Rab15' mRNA 2945 3251 1801 52.13 56.54 34.29 8.43 11.53 12.43 47.65333333 10.79666667 541 730 781 2665.666667 684 7.55E-12 -1.958160129 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0032593///insulin-responsive compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0032482///Rab protein signal transduction+++GO:0032869///cellular response to insulin stimulus+++GO:0072659///protein localization to plasma membrane+++GO:1903307///positive regulation of regulated secretory pathway 104910 104910 'Slc25a47' mRNA 76 73 56 2.82 2.67 2.2 1.55 1.16 1.6 2.563333333 1.436666667 48 35 48 68.33333333 43.66666667 0.067016411 -0.65457874 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015227///acyl carnitine transmembrane transporter activity GO:0006844///acyl carnitine transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:1902616///acyl carnitine transmembrane transport 104923 104923 'Adi1' mRNA 2739.54 2931.33 2872.77 95.08 100.29 105.77 76.06 76.97 76.05 100.38 76.36 2518.41 2487.13 2436.53 2847.88 2480.69 0.003502046 -0.211835356 00270///Cysteine and methionine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005506///iron ion binding+++GO:0010309///acireductone dioxygenase [iron(II)-requiring] activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0006555///methionine metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0019509///L-methionine salvage from methylthioadenosine 104943 104943 'Fam110c' mRNA 341 314 260 7.08 6.41 5.72 4.71 4.58 6.22 6.403333333 5.17 261 248 334 305 281 0.551014042 -0.125703201 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005938///cell cortex GO:0043014///alpha-tubulin binding GO:0030335///positive regulation of cell migration+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060491///regulation of cell projection assembly 105000 105000 'Dnal1' mRNA 409 435 330 3.76 3.94 3.21 1.84 1.47 1.78 3.636666667 1.696666667 230 180 216 391.3333333 208.6666667 4.78E-09 -0.91576087 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0036157///outer dynein arm+++GO:0042995///cell projection GO:0043014///alpha-tubulin binding+++GO:0045504///dynein heavy chain binding GO:0036158///outer dynein arm assembly 105005 105005 'Lratd1' mRNA 80 122 118 1.29 1.94 2.02 1.06 1.22 1.4 1.75 1.226666667 76 85 97 106.6666667 86 0.308769496 -0.324185975 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0000902///cell morphogenesis+++GO:0048870///cell motility 105014 105014 'Rdh14' mRNA 862 966 898 34.74 38.36 38.38 24.04 25.07 23.02 37.16 24.04333333 686 698 635 908.6666667 673 1.39E-05 -0.444817508 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0102354///11-cis-retinol dehydrogenase activity GO:0042572///retinol metabolic process 105083 105083 'Pelo' mRNA 54 79 37 2.02 2.91 1.47 2.83 2.6 2.28 2.133333333 2.57 87 78 68 56.66666667 77.66666667 0.223732414 0.453223968 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0001833///inner cell mass cell proliferation+++GO:0006417///regulation of translation+++GO:0007049///cell cycle+++GO:0007492///endoderm development+++GO:0019827///stem cell population maintenance+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032790///ribosome disassembly+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0060231///mesenchymal to epithelial transition+++GO:0070481///nuclear-transcribed mRNA catabolic process, non-stop decay+++GO:0070651///nonfunctional rRNA decay+++GO:0070966///nuclear-transcribed mRNA catabolic process, no-go decay+++GO:0071025///RNA surveillance+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 105148 105148 'Iars' mRNA 1620 1637 1699 19.79 19.67 22.02 15.39 13.75 14.59 20.49333333 14.57666667 1450 1265 1331 1652 1348.666667 4.10E-04 -0.307347729 00970///Aminoacyl-tRNA biosynthesis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004822///isoleucine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0051020///GTPase binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006428///isoleucyl-tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 105171 105171 'Arrdc3' mRNA 2536 2418 2387 33.27 31.08 33.31 21.59 21.21 19.42 32.55333333 20.74 1887 1809 1640 2447 1778.666667 3.35E-10 -0.472610206 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0031699///beta-3 adrenergic receptor binding GO:0001659///temperature homeostasis+++GO:0015031///protein transport+++GO:0031651///negative regulation of heat generation+++GO:0043588///skin development+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0060613///fat pad development+++GO:0071878///negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0090327///negative regulation of locomotion involved in locomotory behavior+++GO:0120163///negative regulation of cold-induced thermogenesis 105180375 105180375 'Tmem265' mRNA 66 66 47 3.31 3.26 2.5 2.57 1.97 1.99 3.023333333 2.176666667 59 44 44 59.66666667 49 0.476728746 -0.292322797 GO:0016020///membrane+++GO:0016021///integral component of membrane 105193 105193 'Nhlrc1' mRNA 283 299 142 6.93 7.21 3.69 1.51 2.51 2.04 5.943333333 2.02 71 115 93 241.3333333 93 3.80E-07 -1.368896368 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0048471///perinuclear region of cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0001932///regulation of protein phosphorylation+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0031396///regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044260///cellular macromolecule metabolic process+++GO:0045859///regulation of protein kinase activity+++GO:1903076///regulation of protein localization to plasma membrane 105203 105203 'Tasor2' mRNA 471.12 500.2 435.04 3.01 3.17 2.95 2.35 2.21 2.25 3.043333333 2.27 420.02 389 392 468.7866667 400.34 0.07051267 -0.237836126 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 105239 105239 'Rnf44' mRNA 1108 1159 697 15.51 15.98 10.27 12.54 12.17 12.67 13.92 12.46 1028 991 1017 988 1012 0.863090843 0.032979456 GO:0046872///metal ion binding 105242399 105242399 'Gm21083' mRNA 21.09 21.11 27.22 1.08 1.07 1.49 0.6 0.84 0.52 1.213333333 0.653333333 13.39 18.24 11.13 23.14 14.25333333 0.261306098 -0.732115395 105242430 105242430 'Gm38699' mRNA 52.9 58.36 70.44 2.09 2.57 2.66 0.91 1.38 1.31 2.44 1.2 48.29 50.24 54.91 60.56666667 51.14666667 0.529127799 -0.260623985 105242433 105242433 'Gm38702' mRNA 95.35 106.02 86.21 2.33 2.5 2.27 1.53 1.4 1.82 2.366666667 1.583333333 69.65 68.61 77.84 95.86 72.03333333 0.140806445 -0.432119422 105242435 105242435 'Gm38704' mRNA 1.46 2.69 0 0.08 0.14 0 0.15 0.1 0.05 0.073333333 0.1 3.32 2.16 1.15 1.383333333 2.21 0.707152445 1.011279693 105242449 105242449 'Gm21103' mRNA 4.73 7.72 4 0.37 0.6 0.33 0.65 0.32 0.21 0.433333333 0.393333333 10 5 3 5.483333333 6 0.863090843 0.2504497 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105242472 105242472 'Gm11639' mRNA 10 6 5 0.06 0.03 0.03 0.01 0.03 0.02 0.04 0.02 1 5 4 7 3.333333333 0.416564064 -1.066550491 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 105242736 105242736 'Gm6749' mRNA 6.27 8.07 2.2 0.7 0.9 0.26 0.73 0.51 0.33 0.62 0.523333333 7.5 5.05 3.29 5.513333333 5.28 0.953054133 -0.089271791 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus 105242930 105242930 'Gm39002' mRNA 9 7 4 0.13 0.1 0.06 0.07 0.07 0.05 0.096666667 0.063333333 5 5 4 6.666666667 4.666666667 0.70164949 -0.515642037 105242931 105242931 'Gm39003' mRNA 44 34 21 0.73 0.56 0.37 0.29 0.13 0.18 0.553333333 0.2 20 9 12 33 13.66666667 0.027672683 -1.278612468 105243 105243 'Slc9a3' mRNA 303 299 331 3.03 2.95 3.49 3.42 2.99 2.57 3.156666667 2.993333333 390 334 285 311 336.3333333 0.642291739 0.096628711 04964///Proximal tubule bicarbonate reclamation+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0031982///vesicle+++GO:0070062///extracellular exosome GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity+++GO:0030165///PDZ domain binding GO:0002028///regulation of sodium ion transport+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0006898///receptor-mediated endocytosis+++GO:0035725///sodium ion transmembrane transport+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 105243147 105243147 'Gm39147' mRNA 4.34 3.73 2.55 0.39 0.33 0.24 0.08 0.16 0.16 0.32 0.133333333 1 2 2 3.54 1.666666667 0.676607425 -0.846406915 03010///Ribosome+++05171///Coronavirus disease - COVID-19 105243585 105243585 'Gm39469' mRNA 766 745.56 792.06 14.32 13.72 15.71 9.07 8.04 8.59 14.58333333 8.566666667 558 483 512 767.8733333 517.6666667 1.59E-07 -0.583199082 05168///Herpes simplex virus 1 infection 105243794 105243794 'Gm39566' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0016020///membrane+++GO:0016021///integral component of membrane 105243808 105243808 'Gm39572' mRNA 6 13 11 0.29 0.61 0.56 0.08 0.09 0 0.486666667 0.056666667 2 2 0 10 1.333333333 0.022978331 -2.922432612 105243944 105243944 'Gm39653' mRNA 15 15 16 0.85 0.84 0.96 0.15 0 0.1 0.883333333 0.083333333 3 0 2 15.33333333 1.666666667 0.002363749 -3.222395814 105244006 105244006 'Gm39701' mRNA 725.01 718.9 680.58 13.74 13.41 13.68 33.28 30.3 30.92 13.61 31.5 2020.52 1796.52 1817.37 708.1633333 1878.136667 6.34E-67 1.395664507 105244034 105244034 'Gm33887' mRNA 730.59 808.8 683.09 13.53 14.73 13.42 8.72 8.41 9.28 13.89333333 8.803333333 536.24 501.93 544.17 740.8266667 527.4466667 2.86E-06 -0.500268651 105244100 105244100 'Gm39774' mRNA 1 2 0 0.08 0.17 0 0.15 0 0 0.083333333 0.05 2 0 0 1 0.666666667 0.875524583 -0.586675233 GO:0036094///small molecule binding 105244402 105244402 'Gm14444' mRNA 24.28 30.07 23.12 1.16 1.4 1.18 1.18 0.98 0.78 1.246666667 0.98 25.25 22.5 14.13 25.82333333 20.62666667 0.595862439 -0.346360761 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 105244498 105244498 'Gm40095' mRNA 18 19 9 0.48 0.5 0.25 0.35 0.17 0.14 0.41 0.22 15 7 6 15.33333333 9.333333333 0.403273836 -0.722033896 105244600 105244600 'Gm40190' mRNA 6 13 5 0.15 0.32 0.13 0.02 0.14 0.09 0.2 0.083333333 1 6 4 8 3.666666667 0.376099805 -1.113359409 105244717 105244717 'Gm40275' mRNA 0 4 2 0 0.13 0.07 0 0 0 0.066666667 0 0.02 0 0 2 0.006666667 0.294715032 -3.448918583 105244808 105244808 'Gm40353' mRNA 0 1 1 0 0.03 0.03 0.03 0 0.03 0.02 0.02 1 0 1 0.666666667 0.666666667 0.998591786 -0.032941419 105244829 105244829 'Gm40365' mRNA 5.6 24.58 0 0.14 0.62 0 0 0 0.18 0.253333333 0.06 0 0 7.67 10.06 2.556666667 0.625205443 -2.008200065 105244831 105244831 'Gm40367' mRNA 0 8.49 20.07 0 0.2 0.52 1.51 2.63 1.95 0.24 2.03 70.87 121.02 88.93 9.52 93.60666667 0.017142186 3.270355248 105244833 105244833 'Gm40369' mRNA 69.96 99.64 39.79 1.81 2.53 1.09 0.7 0.8 0.91 1.81 0.803333333 30.95 34.9 39.41 69.79666667 35.08666667 0.014690998 -1.001785081 105244844 105244844 'Gm40378' mRNA 10.07 16.35 13.56 0.6 0.96 0.85 0.65 0.94 1.01 0.803333333 0.866666667 12.54 17.71 18.93 13.32666667 16.39333333 0.763772716 0.261144041 105244925 105244925 'Gm40447' mRNA 6.03 8.02 6.06 0.14 0.19 0.15 0.04 0.08 0.04 0.16 0.053333333 2.01 4.04 2.01 6.703333333 2.686666667 0.309221491 -1.326171972 105244931 105244931 'Gm40453' mRNA 24.37 24.82 34.56 0.77 0.77 1.15 1.75 1.66 1.32 0.896666667 1.576666667 63.72 59.18 46.6 27.91666667 56.5 0.014044824 1.014962673 105244947 105244947 'Gm40469' mRNA 257 247 280 9.17 8.69 10.6 6.77 5.88 5.9 9.486666667 6.183333333 218 185 184 261.3333333 195.6666667 0.017371226 -0.433728069 105245 105245 'Txndc5' mRNA 2874 2959 1245 60.15 60.99 27.66 45.58 58.31 57.76 49.6 53.88333333 2503 3129 3072 2359.333333 2901.333333 0.517372796 0.307623004 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003756///protein disulfide isomerase activity GO:0043277///apoptotic cell clearance 105245043 105245043 'Gm2396' mRNA 3 13 6 0.04 0.16 0.08 0.03 0.04 0.14 0.093333333 0.07 3 4 13.18 7.333333333 6.726666667 0.918981582 -0.136047031 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105245097 105245097 'Gm40595' mRNA 87.58 58.61 72.75 3.34 2.2 2.94 3.35 3.01 3.39 2.826666667 3.25 101.12 88.59 98.75 72.98 96.15333333 0.215281986 0.389243067 105245236 105245236 'Gm19802' mRNA 23.33 10.78 19.78 0.36 0.17 0.33 0.1 0.27 0 0.286666667 0.123333333 7.33 19.19 0 17.96333333 8.84 0.329170728 -1.010177194 105245338 105245338 'Gm40811' mRNA 38 51.14 45.25 0.32 0.43 0.41 0.39 0.26 0.52 0.386666667 0.39 53 34.26 68 44.79666667 51.75333333 0.701017653 0.196350333 105245342 105245342 'Gm40814' mRNA 52.02 59.84 70.68 0.9 1.02 1.3 3.47 4.31 3.37 1.073333333 3.716666667 229.91 278.67 215.71 60.84666667 241.43 4.65E-18 1.981930065 105245381 105245381 'Gm40847' mRNA 127.52 143.81 76.92 2.68 3.06 1.8 2.04 1.88 2.07 2.513333333 1.996666667 116.99 102.96 116.18 116.0833333 112.0433333 0.875322463 -0.052553651 105245382 105245382 'Gm9241' mRNA 11.46 13.34 4.63 0.28 0.32 0.12 0.24 0 0.36 0.24 0.2 11.51 0 16.38 9.81 9.296666667 0.973369176 -0.052537005 105245383 105245383 'Zfp996' mRNA 26.05 34.46 21.2 2.03 2.67 1.8 1.27 0.96 1.3 2.166666667 1.176666667 20.87 22.54 24.27 27.23666667 22.56 0.638043203 -0.299106311 105245389 105245389 'Gm40853' mRNA 30.02 27.38 37.03 0.88 0.77 1.23 0.34 0.53 0.65 0.96 0.506666667 13.68 20.35 19.92 31.47666667 17.98333333 0.114887512 -0.869553376 105245393 105245393 'Gm40857' mRNA 0 3.61 1.07 0 0.32 0.1 0.11 0 0.09 0.14 0.066666667 1.49 0 1.11 1.56 0.866666667 0.770914052 -1.006627325 105245406 105245406 'Gm5954' mRNA 11.75 19.41 5.96 0.36 0.58 0.19 0.44 0.31 0.22 0.376666667 0.323333333 16.64 11.57 7.95 12.37333333 12.05333333 0.974745813 -0.038640301 105245424 105245424 'Gm40881' mRNA 0 2 2 0 0.05 0.05 0.05 0.04 0.11 0.033333333 0.066666667 2.37 2 4.97 1.333333333 3.113333333 0.668341081 0.979848731 105245436 105245436 'Gm40892' mRNA 1.04 0 0 0.02 0 0 0.11 0.24 0.05 0.006666667 0.133333333 7.28 15.8 3.19 0.346666667 8.756666667 0.010053188 4.534636761 105245580 105245580 'A930018O16Rik' mRNA 9 6 9 0.49 0.32 0.52 0.19 0.2 0.2 0.443333333 0.196666667 4 4 4 8 4 0.377460133 -1.017331612 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105245673 105245673 'Gm6676' mRNA 1 0.5 0.5 0.09 0.04 0.05 0 0 0 0.06 0 0 0 0 0.666666667 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105245675 105245675 'Gm21560' mRNA 1 4.02 6.01 0.11 0.44 0.71 0.1 0.2 0 0.42 0.1 1 2.01 0 3.676666667 1.003333333 0.345104302 -1.902296756 105245682 105245682 'Gm41099' mRNA 6 4 7 0.12 0.1 0.17 0.14 0.03 0.04 0.13 0.07 8 2 2 5.666666667 4 0.728867167 -0.535522328 105245911 105245911 'Gm41291' mRNA 61.91 87.43 46.98 2.47 3.43 1.98 2.18 2.18 2.76 2.626666667 2.373333333 62.86 61.42 77.1 65.44 67.12666667 0.923114693 0.042321094 105246 105246 'Brd9' mRNA 761 896 900 14.25 16.52 18.13 12.13 10.12 11.86 16.3 11.37 681 548 639 852.3333333 622.6666667 1.12E-04 -0.468658117 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016514///SWI/SNF complex GO:0003674///molecular_function+++GO:0070577///lysine-acetylated histone binding GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 105246049 105246049 'Gm41408' mRNA 140.92 153.86 124.93 1.26 1.35 1.18 0.85 0.66 0.65 1.263333333 0.72 109.81 82.87 81.56 139.9033333 91.41333333 0.010877886 -0.627472291 105246303 105246303 'Gm41607' mRNA 855.61 830.27 696.96 0.96 0.91 0.83 0.68 0.56 0.69 0.9 0.643333333 696.6 564.51 686.01 794.28 649.04 0.010071145 -0.300825863 105246320 105246320 'Gm26637' mRNA 15 4 8 0.42 0.1 0.21 0.84 0.82 0.44 0.243333333 0.7 33 33 18 9 28 0.015716343 1.624421763 105246572 105246572 'Gm41844' mRNA 42.42 37.87 34.72 1.45 1.28 1.26 0.92 1.15 0.75 1.33 0.94 31.08 37.72 24.35 38.33666667 31.05 0.562594367 -0.305360437 105246961 105246961 'AB010352' mRNA 354.76 428.79 440.65 3.73 4.51 5.09 3.16 2.86 2.69 4.443333333 2.903333333 330.79 275.06 274.7 408.0666667 293.5166667 0.001965101 -0.49161896 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105247050 105247050 'Gm42226' mRNA 38.9 36.86 29.02 0.59 0.55 0.47 3.98 3.84 4.41 0.536666667 4.076666667 302.45 285.06 324.1 34.92666667 303.87 1.65E-44 3.135593318 105247180 105247180 'Gm42323' mRNA 27 12 10 0.81 0.33 0.3 0.07 0.1 0.03 0.48 0.066666667 3 4 1 16.33333333 2.666666667 0.006947252 -2.615870133 105247198 105247198 'Gm42337' mRNA 4.5 3.03 3.22 0.27 0.18 0.21 0.28 0.06 0.17 0.22 0.17 5.29 1.08 3.05 3.583333333 3.14 0.924011351 -0.171801185 105247207 105247207 'Gm42346' mRNA 12 9 4 0.26 0.19 0.09 0.15 0.17 0.34 0.18 0.22 8.04 9 17.3 8.333333333 11.44666667 0.673380306 0.448122857 105247240 105247240 'Gm42372' mRNA 68.43 60.41 62.33 0.72 0.63 0.7 0.56 0.43 0.59 0.683333333 0.526666667 60.67 45.56 62.52 63.72333333 56.25 0.627014074 -0.199787729 105278 105278 'Cdk20' mRNA 569 565 608 17.76 17.36 20.2 14.24 16.87 14.19 18.44 15.1 525 607 507 580.6666667 546.3333333 0.52009374 -0.100888536 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001843///neural tube closure+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016310///phosphorylation+++GO:0021508///floor plate formation+++GO:0031076///embryonic camera-type eye development+++GO:0048706///embryonic skeletal system development+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0060021///roof of mouth development+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0061512///protein localization to cilium+++GO:1901620///regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1903317///regulation of protein maturation+++GO:1990403///embryonic brain development 105298 105298 'Epdr1' mRNA 4222 4340 4041 98.95 100.15 100.46 105.15 104.84 104.23 99.85333333 104.74 5160 5024 4952 4201 5045.333333 5.51E-06 0.25291376 GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:1905573///ganglioside GM1 binding GO:0007160///cell-matrix adhesion+++GO:1990764///myofibroblast contraction 105348 105348 'Golm1' mRNA 352 366 379 5.38 5.5 6.14 7.72 9.64 8.82 5.673333333 8.726666667 584 711 646 365.6666667 647 5.36E-10 0.811691674 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006997///nucleus organization+++GO:0019216///regulation of lipid metabolic process 105349 105349 'Akr1c18' mRNA 0 0 1 0 0 0.06 0.41 0.64 1.03 0.02 0.693333333 9 14 22 0.333333333 15 4.18E-04 5.380683087 00140///Steroid hormone biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018636///phenanthrene 9,10-monooxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0032052///bile acid binding+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0045703///ketoreductase activity+++GO:0047006///17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047042///androsterone dehydrogenase (B-specific) activity+++GO:0047086///ketosteroid monooxygenase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047743///chlordecone reductase activity+++GO:0047787///delta4-3-oxosteroid 5beta-reductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0006693///prostaglandin metabolic process+++GO:0006709///progesterone catabolic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0007567///parturition+++GO:0008202///steroid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0016488///farnesol catabolic process+++GO:0034614///cellular response to reactive oxygen species+++GO:0042448///progesterone metabolic process+++GO:0042574///retinal metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0048385///regulation of retinoic acid receptor signaling pathway+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061370///testosterone biosynthetic process+++GO:0071276///cellular response to cadmium ion+++GO:0071277///cellular response to calcium ion+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071379///cellular response to prostaglandin stimulus+++GO:0071384///cellular response to corticosteroid stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0071395///cellular response to jasmonic acid stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071799///cellular response to prostaglandin D stimulus+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:1900053///negative regulation of retinoic acid biosynthetic process+++GO:1904322///cellular response to forskolin+++GO:1990646///cellular response to prolactin+++GO:2000224///regulation of testosterone biosynthetic process+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process 105351 105351 'AW209491' mRNA 828 858 755 23.82 24.38 22.9 14.06 14.58 13.08 23.7 13.90666667 564 572 508 813.6666667 548 2.40E-08 -0.58020535 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105352 105352 'Dusp22' mRNA 617.71 595.58 547.22 17.67 15.38 16.59 16.7 19.02 20.16 16.54666667 18.62666667 758.96 762.78 752.23 586.8366667 757.99 5.52E-04 0.35899337 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031941///filamentous actin+++GO:0061851///leading edge of lamellipodium GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:1990782///protein tyrosine kinase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002710///negative regulation of T cell mediated immunity+++GO:0006470///protein dephosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016311///dephosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0046330///positive regulation of JNK cascade+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050868///negative regulation of T cell activation+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1903996///negative regulation of non-membrane spanning protein tyrosine kinase activity 105372 105372 'Utp15' mRNA 419 426 416 5.55 5.55 5.85 6.09 5.96 6.39 5.65 6.146666667 529 506 538 420.3333333 524.3333333 0.013448834 0.306844137 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:2000234///positive regulation of rRNA processing 105377 105377 'Slf1' mRNA 426 431 433 6.08 6.12 6.55 3.39 3.54 3.5 6.25 3.476666667 268 282 266 430 272 1.00E-06 -0.67295498 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0042405///nuclear inclusion body GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031334///positive regulation of protein complex assembly+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:1990166///protein localization to site of double-strand break+++GO:2000781///positive regulation of double-strand break repair 105387 105387 'Akr1c14' mRNA 22 31 30 0.46 0.7 0.7 0.36 0.47 0.25 0.62 0.36 18 23 13 27.66666667 18 0.291330756 -0.63298657 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018636///phenanthrene 9,10-monooxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0032052///bile acid binding+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0045703///ketoreductase activity+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047042///androsterone dehydrogenase (B-specific) activity+++GO:0047086///ketosteroid monooxygenase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047743///chlordecone reductase activity+++GO:0047787///delta4-3-oxosteroid 5beta-reductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0006693///prostaglandin metabolic process+++GO:0008202///steroid metabolic process+++GO:0021766///hippocampus development+++GO:0042448///progesterone metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process 105418 105418 'E330034G19Rik' mRNA 3 2 0 0.13 0.09 0 0.12 0.12 0.2 0.073333333 0.146666667 3 3 5 1.666666667 3.666666667 0.54901389 1.151609684 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 105428 105428 'Fam149b' mRNA 282.77 322.5 261.54 6.12 6.85 5.83 4.4 3.8 4.48 6.266666667 4.226666667 210.58 202 218.1 288.9366667 210.2266667 0.004834157 -0.466398091 GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium 105439 105439 'Slain1' mRNA 106 119 103 2.03 2.25 2.08 1.36 1.58 1.26 2.12 1.4 81 92 73 109.3333333 82 0.125874076 -0.424472368 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0035371///microtubule plus-end GO:0003674///molecular_function GO:0007020///microtubule nucleation+++GO:0008150///biological_process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization 105440 105440 'Kctd9' mRNA 203 158 152 3.47 2.64 2.74 3.21 2.58 2.74 2.95 2.843333333 219 173 178 171 190 0.57610831 0.140375594 GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0097602///cullin family protein binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0051260///protein homooligomerization 105445 105445 'Dock9' mRNA 2673 2761 2395 16.68 17.08 15.85 9.39 7.37 8.72 16.53666667 8.493333333 1724 1336 1564 2609.666667 1541.333333 1.08E-20 -0.771221605 GO:0012505///endomembrane system+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 105446 105446 'Gmpr2' mRNA 788.3 838.33 859.83 24.28 26.47 28.29 33.61 34.33 33.38 26.34666667 33.77333333 1273.64 1284.88 1244.92 828.82 1267.813333 9.36E-11 0.599840659 00230///Purine metabolism GO:1902560///GMP reductase complex GO:0003824///catalytic activity+++GO:0003920///GMP reductase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006144///purine nucleobase metabolic process+++GO:0006163///purine nucleotide metabolic process+++GO:0009117///nucleotide metabolic process+++GO:0030224///monocyte differentiation+++GO:0032264///IMP salvage+++GO:0046037///GMP metabolic process+++GO:0046038///GMP catabolic process 105450 105450 'Mmrn2' mRNA 242 234 288 3.32 3.16 4.19 5.77 5.24 5.59 3.556666667 5.533333333 484 429 454 254.6666667 455.6666667 4.69E-08 0.822032573 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis 105501 105501 'Abhd4' mRNA 5015 5432 5007 117.89 126.06 125.2 106.19 105.9 107.33 123.05 106.4733333 5156 5020 5048 5151.333333 5074.666667 0.662923881 -0.033109666 GO:0005739///mitochondrion+++GO:0005811///lipid droplet GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0016042///lipid catabolic process+++GO:0055088///lipid homeostasis+++GO:0070291///N-acylethanolamine metabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process 105504 105504 'Exoc5' mRNA 719.41 713.92 679.72 7.93 7.88 8.07 11.41 11.48 12.2 7.96 11.69666667 1161.92 1147.79 1201.55 704.35 1170.42 3.22E-16 0.721992628 05132///Salmonella infection GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030496///midbody GO:0031267///small GTPase binding+++GO:0047485///protein N-terminus binding GO:0001736///establishment of planar polarity+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0072659///protein localization to plasma membrane+++GO:1904019///epithelial cell apoptotic process+++GO:1905515///non-motile cilium assembly 105511 105511 'Fam170b' mRNA 7 1 4 0.24 0.03 0.15 0 0.06 0.12 0.14 0.06 0 2 4 4 2 0.60453774 -1.007090804 GO:0001669///acrosomal vesicle+++GO:0002081///outer acrosomal membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0009566///fertilization+++GO:0080154///regulation of fertilization+++GO:2000344///positive regulation of acrosome reaction 105513 105513 'Chmp7' mRNA 1314 1430 724 26.88 28.79 15.71 15.2 26.44 24.9 23.79333333 22.18 855 1452 1356 1156 1221 0.863090843 0.087226821 04144///Endocytosis+++04217///Necroptosis GO:0000785///chromatin+++GO:0000815///ESCRT III complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005829///cytosol GO:0006900///vesicle budding from membrane+++GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0010458///exit from mitosis+++GO:0015031///protein transport+++GO:0031468///nuclear envelope reassembly+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0045324///late endosome to vacuole transport+++GO:0061952///midbody abscission+++GO:0071168///protein localization to chromatin 105522 105522 'Ankrd28' mRNA 598 556 553 4.88 4.48 4.58 3.54 3.43 3.85 4.646666667 3.606666667 504 472 530 569 502 0.129547593 -0.192689485 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0008150///biological_process 105559 105559 'Mbnl2' mRNA 5640 6084 5718 67.81 71.91 72.97 67.33 63.78 67.51 70.89666667 66.20666667 6439 5955 6248 5814 6214 0.201959279 0.083608782 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing" 105590 105590 'Zfp957' mRNA 1 1 2 0.02 0.02 0.04 0.03 0 0.02 0.026666667 0.016666667 2 0 1 1.333333333 1 0.871583167 -0.456719733 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 105594 105594 'Cphx1' mRNA 2 5 12 0.07 0.17 0.45 0.8 0.44 0.7 0.23 0.646666667 26 14 22 6.333333333 20.66666667 0.038731166 1.667565517 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 105638 105638 'Dph3' mRNA 950.15 938.65 928.25 17 16.91 17.63 14.27 15.42 15.13 17.18 14.94 915.74 974.33 919.33 939.0166667 936.4666667 0.897979579 -0.015629071 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0046872///metal ion binding GO:0002098///tRNA wobble uridine modification+++GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0050709///negative regulation of protein secretion+++GO:0051099///positive regulation of binding 105651 105651 'Ppp1r3e' mRNA 38 48 16 1.18 1.47 0.53 0.35 0.3 0.45 1.06 0.366666667 13 11 16 34 13.33333333 0.022577807 -1.34435891 04910///Insulin signaling pathway+++04931///Insulin resistance GO:0000164///protein phosphatase type 1 complex+++GO:0042587///glycogen granule GO:0004721///phosphoprotein phosphatase activity+++GO:0008157///protein phosphatase 1 binding+++GO:0050196///[phosphorylase] phosphatase activity+++GO:2001069///glycogen binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006470///protein dephosphorylation+++GO:0045725///positive regulation of glycogen biosynthetic process 105653 105653 'Phyhip' mRNA 116 102 65 2.3 1.99 1.37 2.15 1.82 1.67 1.886666667 1.88 125 103 94 94.33333333 107.3333333 0.599059215 0.181436699 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:1990782///protein tyrosine kinase binding GO:0008104///protein localization 105663 105663 'Thtpa' mRNA 749.78 802 708.51 14.57 15.33 14.6 10.77 10.24 10.21 14.83333333 10.40666667 637.98 592 585.55 753.43 605.1766667 0.001698072 -0.32735209 00730///Thiamine metabolism GO:0005737///cytoplasm GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050333///thiamin-triphosphatase activity GO:0006772///thiamine metabolic process+++GO:0016311///dephosphorylation+++GO:0042357///thiamine diphosphate metabolic process 105670 105670 'Rcbtb2' mRNA 1612 1665 1673 30.11 29.95 32.15 20.69 20.84 21.56 30.73666667 21.03 1271 1243 1298 1650 1270.666667 1.82E-06 -0.389823519 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0008150///biological_process 105675 105675 'Ppif' mRNA 675 700 617 25.51 26.32 24.9 27.62 23.1 24.68 25.57666667 25.13333333 834 686 724 664 748 0.174445303 0.160225156 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04613///Neutrophil extracellular trap formation+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05145///Toxoplasmosis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005759///mitochondrial matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0042277///peptide binding "GO:0000413///protein peptidyl-prolyl isomerization+++GO:0002931///response to ischemia+++GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0008637///apoptotic mitochondrial changes+++GO:0010849///regulation of proton-transporting ATPase activity, rotational mechanism+++GO:0010939///regulation of necrotic cell death+++GO:0012501///programmed cell death+++GO:0032780///negative regulation of ATPase activity+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0070266///necroptotic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071277///cellular response to calcium ion+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 105689 105689 'Mycbp2' mRNA 1856 1840 1615 7.06 6.81 6.9 5.33 4.86 5.33 6.923333333 5.173333333 1584 1404 1532 1770.333333 1506.666667 0.002016128 -0.243008313 04361///Axon regeneration GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0004504///peptidylglycine monooxygenase activity+++GO:0004598///peptidylamidoglycolate lyase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016715///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0031418///L-ascorbic acid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" GO:0001519///peptide amidation+++GO:0001666///response to hypoxia+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006518///peptide metabolic process+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007595///lactation+++GO:0008045///motor neuron axon guidance+++GO:0008152///metabolic process+++GO:0009268///response to pH+++GO:0009404///toxin metabolic process+++GO:0010043///response to zinc ion+++GO:0016567///protein ubiquitination+++GO:0018032///protein amidation+++GO:0019538///protein metabolic process+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0022602///ovulation cycle process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032355///response to estradiol+++GO:0032880///regulation of protein localization+++GO:0032922///circadian regulation of gene expression+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042177///negative regulation of protein catabolic process+++GO:0042476///odontogenesis+++GO:0042493///response to drug+++GO:0046688///response to copper ion+++GO:0048511///rhythmic process+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050708///regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0050905///neuromuscular process+++GO:0051384///response to glucocorticoid+++GO:0051493///regulation of cytoskeleton organization+++GO:0060135///maternal process involved in female pregnancy+++GO:0060173///limb development+++GO:1902667///regulation of axon guidance 105704528 105704528 'Gm13090' mRNA 6 3 1 0.19 0.09 0.1 0 0 0 0.126666667 0 0 0 0 3.333333333 0 0.085019638 -4.169889274 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 105722 105722 'Ano6' mRNA 1910 1946 2090 17.62 17.78 20.61 31.81 29.42 30.24 18.67 30.49 3951 3569 3632 1982 3717.333333 7.01E-32 0.89192074 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005227///calcium activated cation channel activity+++GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity "GO:0002407///dendritic cell chemotaxis+++GO:0002543///activation of blood coagulation via clotting cascade+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006821///chloride transport+++GO:0006869///lipid transport+++GO:0006948///induction by virus of host cell-cell fusion+++GO:0007596///blood coagulation+++GO:0017121///phospholipid scrambling+++GO:0030501///positive regulation of bone mineralization+++GO:0032060///bleb assembly+++GO:0034765///regulation of ion transmembrane transport+++GO:0034767///positive regulation of ion transmembrane transport+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0035630///bone mineralization involved in bone maturation+++GO:0035725///sodium ion transmembrane transport+++GO:0043065///positive regulation of apoptotic process+++GO:0045332///phospholipid translocation+++GO:0045794///negative regulation of cell volume+++GO:0046931///pore complex assembly+++GO:0055085///transmembrane transport+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0061588///calcium activated phospholipid scrambling+++GO:0061589///calcium activated phosphatidylserine scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:0070588///calcium ion transmembrane transport+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0097045///phosphatidylserine exposure on blood platelet+++GO:1902476///chloride transmembrane transport+++GO:1903766///positive regulation of potassium ion export across plasma membrane+++GO:2000353///positive regulation of endothelial cell apoptotic process" 105727 105727 'Slc38a1' mRNA 3049 3532 3034 21.86 24.85 23.03 13.41 12.74 12.5 23.24666667 12.88333333 2146 1995 1941 3205 2027.333333 4.93E-21 -0.671595112 04724///Glutamatergic synapse+++04727///GABAergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0098591///external side of apical plasma membrane GO:0005295///neutral amino acid:sodium symporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport+++GO:0006868///glutamine transport+++GO:0007565///female pregnancy+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:1902475///L-alpha-amino acid transmembrane transport 105732 105732 'Fam83h' mRNA 432 414 374 5.09 4.8 4.72 3.39 2.92 2.88 4.87 3.063333333 330 280 272 406.6666667 294 7.80E-04 -0.479371282 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0045095///keratin filament GO:0019901///protein kinase binding+++GO:1990254///keratin filament binding GO:0007165///signal transduction+++GO:0030335///positive regulation of cell migration+++GO:0031214///biomineral tissue development+++GO:0044380///protein localization to cytoskeleton+++GO:0045104///intermediate filament cytoskeleton organization 105734 105734 'Tigd5' mRNA 101 85 49 1.13 0.93 0.58 0.53 0.64 0.58 0.88 0.583333333 55 65 58 78.33333333 59.33333333 0.287684687 -0.400044213 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding GO:0008150///biological_process 105734727 105734727 'Gm27021' mRNA 37.25 45.11 16.12 2.36 2.83 1.08 3.26 2.26 1.49 2.09 2.336666667 58.92 39.92 26.04 32.82666667 41.62666667 0.585292461 0.327741589 GO:0072546///ER membrane protein complex 105782 105782 'Scrib' mRNA 526 530 375 5.12 5.07 3.86 4.12 3.97 4.34 4.683333333 4.143333333 487 459 497 477 481 0.975943699 0.006537652 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0001772///immunological synapse+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0034750///Scrib-APC-beta-catenin complex+++GO:0035748///myelin sheath abaxonal region+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0044291///cell-cell contact zone+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0005515///protein binding "GO:0001768///establishment of T cell polarity+++GO:0001843///neural tube closure+++GO:0001921///positive regulation of receptor recycling+++GO:0002093///auditory receptor cell morphogenesis+++GO:0003382///epithelial cell morphogenesis+++GO:0007275///multicellular organism development+++GO:0008104///protein localization+++GO:0008283///cell proliferation+++GO:0009790///embryo development+++GO:0016080///synaptic vesicle targeting+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0016477///cell migration+++GO:0021747///cochlear nucleus development+++GO:0030154///cell differentiation+++GO:0030859///polarized epithelial cell differentiation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0035089///establishment of apical/basal cell polarity+++GO:0036342///post-anal tail morphogenesis+++GO:0042060///wound healing+++GO:0043065///positive regulation of apoptotic process+++GO:0043113///receptor clustering+++GO:0043615///astrocyte cell migration+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0048488///synaptic vesicle endocytosis+++GO:0048593///camera-type eye morphogenesis+++GO:0050918///positive chemotaxis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0060603///mammary gland duct morphogenesis+++GO:0071896///protein localization to adherens junction+++GO:0090630///activation of GTPase activity+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0098968///neurotransmitter receptor transport postsynaptic membrane to endosome+++GO:0099003///vesicle-mediated transport in synapse+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization" 105785 105785 'Kdelr3' mRNA 579 571 545 24.42 23.76 24.39 29.9 33.96 31.82 24.19 31.89333333 814 902 838 565 851.3333333 2.73E-08 0.581158205 05110///Vibrio cholerae infection GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005046///KDEL sequence binding+++GO:0046923///ER retention sequence binding "GO:0006621///protein retention in ER lumen+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport" 105787 105787 'Prkaa1' mRNA 937 914 912 10.78 10.36 11.14 11.81 11.55 12.64 10.76 12 1181 1127 1224 921 1177.333333 1.47E-04 0.341949516 04068///FoxO signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016324///apical plasma membrane+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0035174///histone serine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047322///[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity+++GO:0050321///tau-protein kinase activity+++GO:0050405///[acetyl-CoA carboxylase] kinase activity GO:0006006///glucose metabolic process+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006914///autophagy+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008610///lipid biosynthetic process+++GO:0009411///response to UV+++GO:0009631///cold acclimation+++GO:0010332///response to gamma radiation+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014823///response to activity+++GO:0015721///bile acid and bile salt transport+++GO:0016055///Wnt signaling pathway+++GO:0016126///sterol biosynthetic process+++GO:0016310///phosphorylation+++GO:0019395///fatty acid oxidation+++GO:0031000///response to caffeine+++GO:0031669///cellular response to nutrient levels+++GO:0032007///negative regulation of TOR signaling+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0034599///cellular response to oxidative stress+++GO:0035404///histone-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0038183///bile acid signaling pathway+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042593///glucose homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0045821///positive regulation of glycolytic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0050995///negative regulation of lipid catabolic process+++GO:0055089///fatty acid homeostasis+++GO:0060627///regulation of vesicle-mediated transport+++GO:0061744///motor behavior+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0062028///regulation of stress granule assembly+++GO:0070050///neuron cellular homeostasis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071277///cellular response to calcium ion+++GO:0071333///cellular response to glucose stimulus+++GO:0071361///cellular response to ethanol+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071417///cellular response to organonitrogen compound+++GO:0071456///cellular response to hypoxia+++GO:0097009///energy homeostasis+++GO:0120188///regulation of bile acid secretion+++GO:1901563///response to camptothecin+++GO:1903109///positive regulation of mitochondrial transcription+++GO:1903829///positive regulation of cellular protein localization+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:1904428///negative regulation of tubulin deacetylation+++GO:1904486///response to 17alpha-ethynylestradiol+++GO:2000758///positive regulation of peptidyl-lysine acetylation 105827 105827 'Amigo2' mRNA 115 123.96 37 2.16 2.32 0.76 1.2 1.4 1.78 1.746666667 1.46 72 82 104 91.98666667 86 0.863090843 -0.081115859 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007420///brain development+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051965///positive regulation of synapse assembly 105833 105833 'Ccdc65' mRNA 1852 1803 1728 63.9 60.78 64.87 8.13 6.44 7.39 63.18333333 7.32 225 177 209 1794.333333 203.6666667 3.18E-208 -3.151708971 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003352///regulation of cilium movement+++GO:0060271///cilium assembly+++GO:0060285///cilium-dependent cell motility+++GO:0070286///axonemal dynein complex assembly 105835 105835 'Sgsm3' mRNA 643 650 592 12.25 12.26 11.99 11.87 9.78 9.82 12.16666667 10.49 705 568 568 628.3333333 613.6666667 0.766483962 -0.046536009 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005921///gap junction GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0032483///regulation of Rab protein signal transduction+++GO:0032486///Rap protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0048227///plasma membrane to endosome transport+++GO:0051726///regulation of cell cycle+++GO:0090630///activation of GTPase activity 105837 105837 'Mtbp' mRNA 137 142 129 2.52 2.9 2.8 2.26 2.18 1.95 2.74 2.13 152 131 123 136 135.3333333 0.948302371 -0.019072037 GO:0000776///kinetochore+++GO:0000785///chromatin GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0031396///regulation of protein ubiquitination+++GO:0034501///protein localization to kinetochore+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0051726///regulation of cell cycle+++GO:0071174///mitotic spindle checkpoint 105841 105841 'Dennd3' mRNA 272 253 242 2.74 2.5 2.62 2.6 2.21 2.41 2.62 2.406666667 289 247 265 255.6666667 267 0.819680628 0.050553354 GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity GO:0008333///endosome to lysosome transport+++GO:0032483///regulation of Rab protein signal transduction+++GO:0044257///cellular protein catabolic process+++GO:0050790///regulation of catalytic activity 105844 105844 'Card10' mRNA 578 591 509 6.39 6.36 5.92 3.86 3.74 4.42 6.223333333 4.006666667 403 382 445 559.3333333 410 2.06E-04 -0.457540337 04064///NF-kappa B signaling pathway GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0050700///CARD domain binding GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042981///regulation of apoptotic process+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1900182///positive regulation of protein localization to nucleus 105847 105847 'Lmf2' mRNA 1441 1443 1513 26.93 26.81 30.23 33.28 31.49 29.51 27.99 31.42666667 2042 1884 1756 1465.666667 1894 4.03E-05 0.355333269 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0051604///protein maturation 105853 105853 'Mal2' mRNA 1042 1141 1201 20.74 22.36 25.36 23.15 26.14 24.99 22.82 24.76 1338 1475 1398 1128 1403.666667 0.003390121 0.301866745 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0045121///membrane raft+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0019911///structural constituent of myelin sheath GO:0042552///myelination+++GO:0045056///transcytosis 105855 105855 'Nckap1l' mRNA 176 142 134 2.02 1.59 1.61 22.02 20.48 20.96 1.74 21.15333333 2228 2019 2053 150.6666667 2100 3.17E-274 3.790106124 04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031209///SCAR complex GO:0005096///GTPase activator activity+++GO:0030295///protein kinase activator activity+++GO:0044877///protein-containing complex binding+++GO:1904841///TORC2 complex binding "GO:0000902///cell morphogenesis+++GO:0001782///B cell homeostasis+++GO:0002262///myeloid cell homeostasis+++GO:0002687///positive regulation of leukocyte migration+++GO:0006935///chemotaxis+++GO:0009410///response to xenobiotic stimulus+++GO:0016477///cell migration+++GO:0030011///maintenance of cell polarity+++GO:0030031///cell projection assembly+++GO:0030593///neutrophil chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030890///positive regulation of B cell proliferation+++GO:0032147///activation of protein kinase activity+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0034101///erythrocyte homeostasis+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0042102///positive regulation of T cell proliferation+++GO:0042327///positive regulation of phosphorylation+++GO:0042493///response to drug+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043318///negative regulation of cytotoxic T cell degranulation+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0045579///positive regulation of B cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0048821///erythrocyte development+++GO:0050853///B cell receptor signaling pathway+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0065003///protein-containing complex assembly+++GO:0070358///actin polymerization-dependent cell motility+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1902624///positive regulation of neutrophil migration+++GO:1904515///positive regulation of TORC2 signaling" 105859 105859 'Csdc2' mRNA 763 747 684 17.08 16.46 16.24 10.08 8.17 8.18 16.59333333 8.81 518 410 407 731.3333333 445 6.05E-10 -0.729142827 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008134///transcription factor binding GO:0006397///mRNA processing+++GO:0043488///regulation of mRNA stability 105886298 105886298 'Cmc4' mRNA 185.82 207.89 190.02 16.72 16.24 17.26 9.38 10.71 10.27 16.74 10.12 117.69 142.9 129.61 194.5766667 130.0666667 0.003877748 -0.594884409 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space 105940408 105940408 'Gm20498' mRNA 80.54 89.78 90.43 3.66 4.87 5.09 4.61 3.38 3.32 4.54 3.77 98.59 74.21 64 86.91666667 78.93333333 0.68870794 -0.150376571 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031594///neuromuscular junction+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0070699///type II activin receptor binding GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002090///regulation of receptor internalization+++GO:0002092///positive regulation of receptor internalization+++GO:0006605///protein targeting+++GO:0006897///endocytosis+++GO:0007028///cytoplasm organization+++GO:0007266///Rho protein signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0008593///regulation of Notch signaling pathway+++GO:0010596///negative regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030100///regulation of endocytosis+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0043113///receptor clustering+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0048312///intracellular distribution of mitochondria+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:2000010///positive regulation of protein localization to cell surface 105943584 105943584 'Gm45927' mRNA 24.34 23.8 38.19 0.46 0.44 0.76 0.25 0.47 0.57 0.553333333 0.43 15.49 27.57 33.66 28.77666667 25.57333333 0.777385172 -0.199254902 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0015031///protein transport 105980076 105980076 'Gm45929' mRNA 8.57 0 7.68 0.33 0 0.31 0.47 0.5 0.55 0.213333333 0.506666667 14.27 14.84 15.96 5.416666667 15.02333333 0.132578549 1.492875084 04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0030054///cell junction "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0042826///histone deacetylase binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 105988 105988 'Espl1' mRNA 19 24 14 0.15 0.19 0.12 1.7 1.79 1.83 0.153333333 1.773333333 249 253 256 19 252.6666667 1.66E-42 3.725813901 04110///Cell cycle+++04114///Oocyte meiosis+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0072686///mitotic spindle GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0000070///mitotic sister chromatid segregation+++GO:0000212///meiotic spindle organization+++GO:0000278///mitotic cell cycle+++GO:0006508///proteolysis+++GO:0007059///chromosome segregation+++GO:0007127///meiosis I+++GO:0045143///homologous chromosome segregation+++GO:0051307///meiotic chromosome separation 106014 106014 'Tafa5' mRNA 504.67 507.95 475.58 5.68 5.37 5.27 3.37 3.33 3.35 5.44 3.35 363.98 303 329 496.0666667 331.9933333 3.89E-06 -0.591022404 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0005125///cytokine activity+++GO:0048018///receptor ligand activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0061044///negative regulation of vascular wound healing+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration 106021 106021 'Topors' mRNA 921 1023 950 13.07 14.24 14.25 13.38 13.21 14.16 13.85333333 13.58333333 1088 1050 1112 964.6666667 1083.333333 0.114947937 0.155658342 GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005814///centriole+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body GO:0003677///DNA binding+++GO:0003823///antigen binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0044547///DNA topoisomerase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0016925///protein sumoylation+++GO:0034504///protein localization to nucleus+++GO:0042127///regulation of cell proliferation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0051457///maintenance of protein location in nucleus+++GO:0070936///protein K48-linked ubiquitination" 106025 106025 'Sharpin' mRNA 778 847 752 26.45 28.49 27.46 28.35 27.35 28.36 27.46666667 28.02 960 897 921 792.3333333 926 0.029015471 0.213937458 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0071797///LUBAC complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0007005///mitochondrion organization+++GO:0007420///brain development+++GO:0008544///epidermis development+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0030262///apoptotic nuclear changes+++GO:0031424///keratinization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050728///negative regulation of inflammatory response+++GO:0097039///protein linear polyubiquitination+++GO:2000348///regulation of CD40 signaling pathway 106039 106039 'Gga1' mRNA 1526 1578 1300 27.57 28.07 24.95 25.69 25.64 24.63 26.86333333 25.32 1635 1593 1519 1468 1582.333333 0.277700791 0.099496255 04142///Lysosome GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding "GO:0006886///intracellular protein transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0034394///protein localization to cell surface+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045732///positive regulation of protein catabolic process+++GO:1901998///toxin transport+++GO:1903441///protein localization to ciliary membrane" 106042 106042 'Prickle1' mRNA 260.87 242.68 246.34 2.7 2.66 2.94 1.38 1.99 1.63 2.766666667 1.666666667 152.93 199.89 184.68 249.9633333 179.1666667 0.00950624 -0.493499348 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0001843///neural tube closure+++GO:0006606///protein import into nucleus+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035904///aorta development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060976///coronary vasculature development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000691///negative regulation of cardiac muscle cell myoblast differentiation" 106052 106052 'Fbxo4' mRNA 197 210 153 3.11 3.26 2.56 3.29 3.49 3.59 2.976666667 3.456666667 240 248 253 186.6666667 247 0.031934386 0.39785172 04120///Ubiquitin mediated proteolysis GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0000723///telomere maintenance+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007568///aging+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0019725///cellular homeostasis+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0071479///cellular response to ionizing radiation+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1902916///positive regulation of protein polyubiquitination+++GO:2000001///regulation of DNA damage checkpoint 106064 106064 'AW549877' mRNA 1341 1420 1281 14.1 14.68 14.29 10.06 9.58 10.04 14.35666667 9.893333333 1102 1025 1065 1347.333333 1064 1.59E-05 -0.351725414 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 106068 106068 'Slc45a4' mRNA 570 531 574 4.34 4.03 4.76 3.47 3.25 3.55 4.376666667 3.423333333 515 471 519 558.3333333 501.6666667 0.210293247 -0.168452281 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008506///sucrose:proton symporter activity GO:0015770///sucrose transport 106073 106073 'Mfsd5' mRNA 788 798 491 26.18 26.13 17.31 25.27 31.28 30.77 23.20666667 29.10666667 874 1056 1030 692.3333333 986.6666667 4.81E-04 0.511245092 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0015098///molybdate ion transmembrane transporter activity GO:0006811///ion transport+++GO:0008150///biological_process+++GO:0015689///molybdate ion transport 106143 106143 'Cggbp1' mRNA 1458 1409 1187 17.79 16.91 15.36 16.95 17.7 18.43 16.68666667 17.69333333 1599 1631 1684 1351.333333 1638 0.001566043 0.269509324 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0040029///regulation of gene expression, epigenetic+++GO:0090579///dsDNA loop formation" 106200 106200 'Txndc11' mRNA 1146 1234 410 21.17 22.42 8.96 10.1 12.75 13.7 17.51666667 12.18333333 577 775 827 930 726.3333333 0.580371252 -0.34270112 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 106205 106205 'Zc3h7a' mRNA 1216 1155 1285 17.46 16.31 19.56 21.59 17.93 20.37 17.77666667 19.96333333 1731 1404 1582 1218.666667 1572.333333 4.33E-04 0.351186625 GO:0005575///cellular_component GO:0035198///miRNA binding+++GO:0046872///metal ion binding GO:0010608///posttranscriptional regulation of gene expression+++GO:0035196///production of miRNAs involved in gene silencing by miRNA 106248 106248 'Qtrt2' mRNA 617 623 609 11.1 11.03 11.62 7.2 6.64 6.24 11.25 6.693333333 461 414 386 616.3333333 420.3333333 1.83E-06 -0.565212164 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex "GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008479///queuine tRNA-ribosyltransferase activity+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0101030///tRNA-guanine transglycosylation 106264 106264 '0610012G03Rik' mRNA 1154 1095 1110 47.05 44.04 48.01 58.25 63.01 57.24 46.36666667 59.5 1641 1732 1560 1119.666667 1644.333333 1.82E-10 0.542565164 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 106298 106298 'Rrn3' mRNA 1490 1391 1430 22.64 20.81 23.27 20.6 19.64 18.62 22.24 19.62 1547 1441 1353 1437 1447 0.982883688 -0.003292201 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0001042///RNA polymerase I core binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0070063///RNA polymerase binding "GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0001701///in utero embryonic development+++GO:0006352///DNA-templated transcription, initiation+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0007000///nucleolus organization+++GO:0007028///cytoplasm organization+++GO:0008283///cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0042254///ribosome biogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048872///homeostasis of number of cells+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:2000142///regulation of DNA-templated transcription, initiation" 106326 106326 'Osbpl11' mRNA 2201 2313 2108 26.12 27 26.54 10.58 13.48 13.51 26.55333333 12.52333333 1026 1277 1269 2207.333333 1190.666667 1.96E-21 -0.899145626 GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0015918///sterol transport+++GO:0045444///fat cell differentiation 106338 106338 'Nsun3' mRNA 205 227 211 4.52 4.83 4.47 6.35 5.62 4.45 4.606666667 5.473333333 305 260 228 214.3333333 264.3333333 0.124539892 0.289242089 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005762///mitochondrial large ribosomal subunit GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016428///tRNA (cytosine-5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0002127///tRNA wobble base cytosine methylation+++GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0070129///regulation of mitochondrial translation 106344 106344 'Rfc4' mRNA 147.09 131.08 140.13 7.41 6.52 7.49 9.9 13.15 10.22 7.14 11.09 225.6 292.28 225.2 139.4333333 247.6933333 3.97E-05 0.817346191 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005663///DNA replication factor C complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031390///Ctf18 RFC-like complex+++GO:0031391///Elg1 RFC-like complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0032508///DNA duplex unwinding+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 106347 106347 'Ildr1' mRNA 1597 1744 1762 29.79 32.1 34.88 22.19 21.13 21.7 32.25666667 21.67333333 1303 1240 1280 1701 1274.333333 5.43E-07 -0.430534842 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0061689///tricellular tight junction GO:0042802///identical protein binding+++GO:0070506///high-density lipoprotein particle receptor activity GO:0006897///endocytosis+++GO:0090277///positive regulation of peptide hormone secretion+++GO:1990830///cellular response to leukemia inhibitory factor 106369 106369 'Ypel1' mRNA 266.19 266.05 175.64 5.15 5.17 3.4 1.5 2.78 2.57 4.573333333 2.283333333 93.5 166.87 141.87 235.96 134.08 7.53E-04 -0.820213407 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0072659///protein localization to plasma membrane 106389 106389 'Eaf2' mRNA 71.72 95.51 52.71 2.87 4.09 2.64 2.54 3.07 2.71 3.2 2.773333333 69.79 78.67 70.74 73.31333333 73.06666667 0.991284858 -0.008081779 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex+++GO:0016607///nuclear speck+++GO:0032783///ELL-EAF complex GO:0003711///transcription elongation regulator activity+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030308///negative regulation of cell growth+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0097193///intrinsic apoptotic signaling pathway" 106393 106393 'Srl' mRNA 74 91 64 0.76 1.01 0.79 0.69 0.73 0.78 0.853333333 0.733333333 82.02 99 84.98 76.33333333 88.66666667 0.553559902 0.205319349 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0043231///intracellular membrane-bounded organelle GO:0005525///GTP binding GO:0002115///store-operated calcium entry+++GO:0006897///endocytosis+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0016197///endosomal transport 106407 106407 'Slc51a' mRNA 395 459 415 15.05 17.25 16.78 5.24 5.44 5.14 16.36 5.273333333 158 160 150 423 156 9.98E-22 -1.450476305 04976///Bile secretion GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0032991///protein-containing complex GO:0005215///transporter activity+++GO:0005515///protein binding+++GO:0015125///bile acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0006810///transport+++GO:0015721///bile acid and bile salt transport+++GO:0032782///bile acid secretion+++GO:0055085///transmembrane transport+++GO:0071702///organic substance transport 106489 106489 'Sft2d1' mRNA 779 821 769 46.96 48.93 49.21 90.52 87.03 88.27 48.36666667 88.60666667 1720 1613 1622 789.6666667 1651.666667 8.75E-40 1.052779797 GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 106504 106504 'Stk38' mRNA 1010 1136 1154 16.51 18.33 19.93 24.65 25.14 23.86 18.25666667 24.55 1739 1735 1634 1100 1702.666667 9.75E-12 0.616433869 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0046872///metal ion binding GO:0006464///cellular protein modification process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity 106512 106512 'Gpsm3' mRNA 194 233 112 8.69 10.3 5.32 22.31 24.39 22.71 8.103333333 23.13666667 572 610 563 179.6666667 581.6666667 4.02E-21 1.695657528 GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0030695///GTPase regulator activity GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050790///regulation of catalytic activity+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 106522 106522 'Pkdcc' mRNA 73 59 57 1.79 1.42 1.48 1.83 1.24 2.29 1.563333333 1.786666667 86 57 104 63 82.33333333 0.304305817 0.374156486 GO:0005576///extracellular region+++GO:0005794///Golgi apparatus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0015031///protein transport+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030501///positive regulation of bone mineralization+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035108///limb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0048286///lung alveolus development+++GO:0048566///embryonic digestive tract development+++GO:0060021///roof of mouth development 106529 106529 'Tecr' mRNA 9282 9214 8883 491.42 482.78 499.85 363.47 374.66 365.03 491.35 367.72 7891 7936 7663 9126.333333 7830 1.55E-05 -0.232621311 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0102758///very-long-chain enoyl-CoA reductase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0042761///very long-chain fatty acid biosynthetic process 106557 106557 'Ldhal6b' mRNA 1 1 0 0.04 0.04 0 0.04 0.07 0.15 0.026666667 0.086666667 1 2 4 0.666666667 2.333333333 0.468266986 1.82357446 00010///Glycolysis / Gluconeogenesis+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0003824///catalytic activity+++GO:0004459///L-lactate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0019752///carboxylic acid metabolic process 106564 106564 'Ppcs' mRNA 638 632 578 29.33 26.83 27.45 25.99 28.95 26.68 27.87 27.20666667 670 702 638 616 670 0.375234203 0.111150841 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004632///phosphopantothenate--cysteine ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0003015///heart process+++GO:0006085///acetyl-CoA biosynthetic process+++GO:0015937///coenzyme A biosynthetic process 106565 106565 'Dlk2' mRNA 2217 2379 2134 90.65 95.97 92.64 13.8 10.95 12.37 93.08666667 12.37333333 390 304 334 2243.333333 342.6666667 8.71E-193 -2.722968926 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0045598///regulation of fat cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway 106572 106572 'Rab31' mRNA 1231 1268 1342 19.86 20.32 23.26 51.37 51.23 47.62 21.14666667 50.07333333 3615 3552 3260 1280.333333 3475.666667 1.59E-73 1.426511021 04144///Endocytosis GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0036186///early phagosome membrane+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding "GO:0006886///intracellular protein transport+++GO:0031623///receptor internalization+++GO:0032869///cellular response to insulin stimulus+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045055///regulated exocytosis+++GO:0048193///Golgi vesicle transport+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0090382///phagosome maturation" 106581 106581 'Fam234a' mRNA 5670 5875 5784 113.11 115.12 122.24 96.7 97.48 97.15 116.8233333 97.11 5583 5505 5440 5776.333333 5509.333333 0.230883957 -0.080934185 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 106582 106582 'Nrm' mRNA 60 54 85 2.43 2.16 3.65 12.73 14.11 12.48 2.746666667 13.10666667 354 388 340 66.33333333 360.6666667 1.15E-31 2.424915714 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005652///nuclear lamina+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003674///molecular_function GO:0008150///biological_process 106583 106583 'Scaf8' mRNA 954 982 751 10.47 10.6 8.74 6.51 7.99 6.45 9.936666667 6.983333333 683 819 655 895.6666667 719 0.01025411 -0.322148903 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005849///mRNA cleavage factor complex+++GO:0016363///nuclear matrix GO:0000993///RNA polymerase II complex binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0019904///protein domain specific binding+++GO:0043175///RNA polymerase core enzyme binding+++GO:0070063///RNA polymerase binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding "GO:0006366///transcription by RNA polymerase II+++GO:0006369///termination of RNA polymerase II transcription+++GO:0006378///mRNA polyadenylation+++GO:0006379///mRNA cleavage+++GO:0006397///mRNA processing+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:2000805///negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled" 106585 106585 'Ankrd12' mRNA 2519 2465.01 2425.01 15.39 14.92 15.76 10.31 10.88 10.92 15.35666667 10.70333333 1946 1978.01 1945.01 2469.673333 1956.34 5.75E-07 -0.34792105 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 106618 106618 'Wdr90' mRNA 632 599 579 5.52 5.15 5.37 2.48 2.34 2.46 5.346666667 2.426666667 327 301 314 603.3333333 314 9.28E-16 -0.953986006 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0030030///cell projection organization+++GO:0060271///cilium assembly 106628 106628 'Trip10' mRNA 559 504 557 14.47 12.69 14.85 20.85 22.58 22.07 14.00333333 21.83333333 926 976 963 540 955 2.65E-14 0.809537246 04910///Insulin signaling pathway GO:0001891///phagocytic cup+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0001837///epithelial to mesenchymal transition+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0030036///actin cytoskeleton organization+++GO:0042538///hyperosmotic salinity response+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development 106633 106633 'Ift140' mRNA 835 757 813 7.3 6.74 7.67 3.57 4.03 3.8 7.236666667 3.8 457 488 479 801.6666667 474.6666667 5.71E-12 -0.768764004 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030991///intraciliary transport particle A+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097542///ciliary tip+++GO:0097730///non-motile cilium GO:0003674///molecular_function GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0021532///neural tube patterning+++GO:0030030///cell projection organization+++GO:0031076///embryonic camera-type eye development+++GO:0035108///limb morphogenesis+++GO:0035721///intraciliary retrograde transport+++GO:0035845///photoreceptor cell outer segment organization+++GO:0042073///intraciliary transport+++GO:0042733///embryonic digit morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1902017///regulation of cilium assembly+++GO:1905515///non-motile cilium assembly+++GO:1990403///embryonic brain development 106639 106639 'Vmac' mRNA 1782 1919 1756 49.47 52.63 51.81 33.72 30.99 32.48 51.30333333 32.39666667 1400 1255 1305 1819 1320 3.96E-10 -0.474541115 GO:0005737///cytoplasm+++GO:0045098///type III intermediate filament GO:0008150///biological_process 106648 106648 'Cyp4f15' mRNA 12 3 5 0.34 0.08 0.23 0.74 1.14 0.65 0.216666667 0.843333333 24 42 21 6.666666667 29 0.002490688 2.116844406 GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005504///fatty acid binding+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0018685///alkane 1-monooxygenase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050051///leukotriene-B4 20-monooxygenase activity+++GO:0052869///arachidonic acid omega-hydroxylase activity+++GO:0052871///alpha-tocopherol omega-hydroxylase activity+++GO:0052872///tocotrienol omega-hydroxylase activity" GO:0019369///arachidonic acid metabolic process+++GO:0036101///leukotriene B4 catabolic process+++GO:0042361///menaquinone catabolic process+++GO:0042376///phylloquinone catabolic process+++GO:0042377///vitamin K catabolic process+++GO:0097267///omega-hydroxylase P450 pathway+++GO:1905344///prostaglandin catabolic process 106672 106672 'AI413582' mRNA 723 629 648 82.99 72.27 79.16 115 111.06 99.69 78.14 108.5833333 1130 1068 943 666.6666667 1047 1.24E-09 0.638596595 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 106707 106707 'Rpusd1' mRNA 558.11 513.93 482.43 17.57 15.82 16.43 14.36 15.12 15.02 16.60666667 14.83333333 512.08 520.83 519.44 518.1566667 517.45 0.939175627 -0.012045541 GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0009451///RNA modification 106722 106722 'Mpig6b' mRNA 56 61 43 1.29 1.36 1.1 0.33 0.55 0.36 1.25 0.413333333 14 25 17 53.33333333 18.66666667 6.01E-04 -1.516693469 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007229///integrin-mediated signaling pathway+++GO:0007596///blood coagulation+++GO:0009968///negative regulation of signal transduction+++GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030220///platelet formation+++GO:0035855///megakaryocyte development 106757 106757 'Catsperd' mRNA 15 21 20 0.38 0.57 0.52 0.2 0.1 0.15 0.49 0.15 11 5 6 18.66666667 7.333333333 0.069108062 -1.36738494 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0048240///sperm capacitation 106759 106759 'Ticam1' mRNA 426 461 432 8.3 8.84 8.93 9.89 10.15 10.66 8.69 10.23333333 584 585 609 439.6666667 592.6666667 3.57E-04 0.419471759 04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04936///Alcoholic liver disease+++05133///Pertussis+++05135///Yersinia infection+++05142///Chagas disease+++05160///Hepatitis C+++05161///Hepatitis B+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0097342///ripoptosome GO:0003953///NAD+ nucleosidase activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0030890///positive regulation of B cell proliferation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032481///positive regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0032722///positive regulation of chemokine production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0050871///positive regulation of B cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0097190///apoptotic signaling pathway+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 106763 106763 'Ttbk1' mRNA 231.68 292.47 210.26 1.53 1.79 1.36 0.75 0.76 0.76 1.56 0.756666667 138.35 134.19 139.16 244.8033333 137.2333333 9.56E-06 -0.841820087 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0048156///tau protein binding+++GO:0050321///tau-protein kinase activity GO:0006468///protein phosphorylation+++GO:0007611///learning or memory+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0032273///positive regulation of protein polymerization+++GO:1903980///positive regulation of microglial cell activation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 106766 106766 'Stap2' mRNA 636.95 616.53 565.67 20.31 19.22 18.98 25.44 28.03 26.34 19.50333333 26.60333333 957.07 1012.65 955.78 606.3833333 975.1666667 2.82E-12 0.676591479 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0035591///signaling adaptor activity 106794 106794 'Dhx57' mRNA 423 492 434 4.87 5.54 5.65 4.99 4.09 4.2 5.353333333 4.426666667 493 412 407 449.6666667 437.3333333 0.768331902 -0.052566981 GO:0005622///intracellular GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding 106795 106795 'Tcf19' mRNA 126 124 136 4.41 4.33 5.15 13.05 10.93 12.56 4.63 12.18 430 348 397 128.6666667 391.6666667 4.74E-22 1.590812573 GO:0005634///nucleus GO:0000082///G1/S transition of mitotic cell cycle+++GO:0010468///regulation of gene expression+++GO:0044342///type B pancreatic cell proliferation 106821 106821 'Oard1' mRNA 1496 1311 1340 76.21 66.92 74.35 49.27 49.18 50.45 72.49333333 49.63333333 1075 1074 1095 1382.333333 1081.333333 4.30E-05 -0.366032547 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0090734///site of DNA damage GO:0001883///purine nucleoside binding+++GO:0016787///hydrolase activity+++GO:0061463///O-acetyl-ADP-ribose deacetylase activity GO:0006974///cellular response to DNA damage stimulus+++GO:0042278///purine nucleoside metabolic process+++GO:0051725///protein de-ADP-ribosylation 106840 106840 'Unc119b' mRNA 4683 5145 4886 69.74 75.38 77.19 32.69 33.45 31.96 74.10333333 32.7 2526 2525 2392 4904.666667 2481 2.94E-52 -0.995478956 GO:0005929///cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection GO:0008289///lipid binding GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0042953///lipoprotein transport+++GO:0060271///cilium assembly 106861 106861 'Abhd3' mRNA 229 291 287 7.43 9.2 9.33 7.49 6.54 7.56 8.653333333 7.196666667 277 239 273 269 263 0.850371723 -0.047432443 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004623///phospholipase A2 activity+++GO:0008126///acetylesterase activity+++GO:0008970///phospholipase A1 activity+++GO:0016787///hydrolase activity+++GO:0034338///short-chain carboxylesterase activity+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0044255///cellular lipid metabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0051793///medium-chain fatty acid catabolic process 106869 106869 'Tnfaip8' mRNA 535 516 519 15.89 14.89 16.31 42.96 40.53 42.8 15.69666667 42.09666667 1740 1519 1632 523.3333333 1630.333333 8.51E-75 1.626274773 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0006915///apoptotic process+++GO:0032611///interleukin-1 beta production+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050830///defense response to Gram-positive bacterium 106877 106877 'Afap1l1' mRNA 1617 1602 1483 25.89 25.23 25.18 25.68 26.2 25.77 25.43333333 25.88333333 1846 1840 1794 1567.333333 1826.666667 0.004892479 0.210255201 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0008150///biological_process 106878 106878 'Smim3' mRNA 1448 1447 1482 41.67 41.2 45.31 36.57 38.84 39.77 42.72666667 38.39333333 1463 1505 1537 1459 1501.666667 0.804537619 0.02895708 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0008150///biological_process 106894 106894 'Hmgxb3' mRNA 757.45 750.21 751.83 7.81 7.68 8.58 6.67 6.45 6.75 8.023333333 6.623333333 710.51 702.93 726.99 753.1633333 713.4766667 0.453278106 -0.091077195 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 106931 106931 'Kctd1' mRNA 211 199 120 5.96 4.47 3.53 2.35 2.87 3.05 4.653333333 2.756666667 110 123 133 176.6666667 122 0.031851361 -0.534630603 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0034451///centriolar satellite+++GO:0045171///intercellular bridge GO:0003714///transcription corepressor activity+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding "GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051260///protein homooligomerization" 106947 106947 'Slc39a3' mRNA 1338 1405 1317 19.71 20.37 20.51 10.76 10.86 10.15 20.19666667 10.59 842 831 769 1353.333333 814 2.93E-18 -0.745034205 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0030001///metal ion transport+++GO:0043029///T cell homeostasis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0055085///transmembrane transport+++GO:0060173///limb development+++GO:0071577///zinc ion transmembrane transport 106952 106952 'Arap3' mRNA 99 103 87 1.01 1.04 0.95 3.32 3.65 3.35 1 3.44 374 402 367 96.33333333 381 1.43E-31 1.974763571 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04144///Endocytosis GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0042995///cell projection "GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0030336///negative regulation of cell migration+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 106957 106957 'Slc39a6' mRNA 808 876 849 11.25 12 12.54 10.5 10.28 10.1 11.93 10.29333333 868 830 808 844.3333333 835.3333333 0.84385141 -0.028205309 05010///Alzheimer disease+++05012///Parkinson disease GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0071578///zinc ion import across plasma membrane 107022 107022 'Gramd3' mRNA 596 631 675 12.7 13.24 15.26 12.21 12.52 12.5 13.73333333 12.41 659 660 653 634 657.3333333 0.815135811 0.037813785 GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0008150///biological_process 107029 107029 'Me2' mRNA 458 459 370 3.12 3.07 2.68 5.1 5.19 4.48 2.956666667 4.923333333 857 850 729 429 812 2.55E-15 0.912176163 00620///Pyruvate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004470///malic enzyme activity+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051287///NAD binding GO:0006090///pyruvate metabolic process+++GO:0006108///malate metabolic process+++GO:0008152///metabolic process+++GO:1902031///regulation of NADP metabolic process 107035 107035 'Fbxo38' mRNA 1172 1145 1192 14.38 13.93 15.52 13.21 12.86 12.58 14.61 12.88333333 1238 1190 1138 1169.666667 1188.666667 0.936012214 0.009679194 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002842///positive regulation of T cell mediated immune response to tumor cell+++GO:0010976///positive regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 107045 107045 'Lars' mRNA 1285 1173 1190 17.76 15.94 17.44 19.99 18.21 18.17 17.04666667 18.79 1665 1482 1466 1216 1537.666667 1.73E-04 0.325496065 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016604///nuclear body+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004819///glutamine-tRNA ligase activity+++GO:0004823///leucine-tRNA ligase activity+++GO:0005096///GTPase activator activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006425///glutaminyl-tRNA aminoacylation+++GO:0006429///leucyl-tRNA aminoacylation+++GO:0008361///regulation of cell size+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0043547///positive regulation of GTPase activity+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:1904263///positive regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 107047 107047 'Psmg2' mRNA 550 596 534 31.31 33.79 32.28 37.58 33.65 42.35 32.46 37.86 758 657 824 560 746.3333333 5.70E-04 0.403027399 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0101031///chaperone complex GO:0060090///molecular adaptor activity GO:0007094///mitotic spindle assembly checkpoint+++GO:0043066///negative regulation of apoptotic process+++GO:0043248///proteasome assembly+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051726///regulation of cell cycle 107065 107065 'Lrrtm2' mRNA 129.44 142.52 131.41 1.21 1.31 1.31 1.33 0.99 1.16 1.276666667 1.16 163.15 118.61 138.51 134.4566667 140.09 0.869540119 0.045929919 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0042043///neurexin family protein binding GO:0002091///negative regulation of receptor internalization+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0060291///long-term synaptic potentiation+++GO:0099151///regulation of postsynaptic density assembly 107071 107071 'Wdr74' mRNA 523 599 612 26.66 30.25 33.18 36.07 35.88 34.59 30.03 35.51333333 811 786 750 578 782.3333333 2.65E-04 0.422468363 "GO:0000176///nuclear exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor" GO:0003674///molecular_function GO:0001825///blastocyst formation+++GO:0006364///rRNA processing+++GO:0016070///RNA metabolic process+++GO:0042273///ribosomal large subunit biogenesis 107094 107094 'Rrp12' mRNA 579 565 568 5.93 5.75 6.1 3.33 3.35 3.82 5.926666667 3.5 327 326 364 570.6666667 339 7.20E-10 -0.763481214 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0006364///rRNA processing 107173 107173 'Gpr137' mRNA 1134.18 1063.23 1010.28 43.32 39.97 41.27 37.46 40.69 38.04 41.52 38.73 1122.55 1182.6 1094.81 1069.23 1133.32 0.503822498 0.073115036 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045779///negative regulation of bone resorption+++GO:1904263///positive regulation of TORC1 signaling 107182 107182 'Btaf1' mRNA 704 744 587 4.61 5.08 4.25 4.06 4.66 4.58 4.646666667 4.433333333 660.01 782 745 678.3333333 729.0033333 0.491590134 0.097839548 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0035562///negative regulation of chromatin binding+++GO:0045892///negative regulation of transcription, DNA-templated" 107197 107197 'Uqcc3' mRNA 749 766 717 60.66 61.46 61.62 56.52 67.54 61.45 61.24666667 61.83666667 799 930 839 744 856 0.091156146 0.192502565 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0016301///kinase activity+++GO:0070300///phosphatidic acid binding+++GO:1901612///cardiolipin binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0006754///ATP biosynthetic process+++GO:0016310///phosphorylation+++GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0042407///cristae formation" 107221 107221 'Ffar4' mRNA 3 11 10 0.13 0.47 0.46 1.05 0.5 0.89 0.353333333 0.813333333 28 13 23 8 21.33333333 0.065521437 1.393045354 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0004930///G protein-coupled receptor activity+++GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0008527///taste receptor activity+++GO:1990763///arrestin family protein binding GO:0001818///negative regulation of cytokine production+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010827///regulation of glucose transmembrane transport+++GO:0030154///cell differentiation+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0036321///ghrelin secretion+++GO:0043066///negative regulation of apoptotic process+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045444///fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046879///hormone secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0050912///detection of chemical stimulus involved in sensory perception of taste+++GO:0070094///positive regulation of glucagon secretion+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090275///negative regulation of somatostatin secretion+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis 107227 107227 'Macrod1' mRNA 214 207 76 10.24 9.83 3.9 1.59 1.12 2.19 7.99 1.633333333 39 27 51 165.6666667 39 5.89E-09 -2.080428061 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019213///deacetylase activity" GO:0006974///cellular response to DNA damage stimulus+++GO:0042278///purine nucleoside metabolic process+++GO:0051725///protein de-ADP-ribosylation 107239 107239 'Carns1' mRNA 990 998 864 9.59 9.69 9.2 6.17 5.56 5.14 9.493333333 5.623333333 672 589 560 950.6666667 607 7.01E-11 -0.657804759 00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00410///beta-Alanine metabolism GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0047730///carnosine synthase activity+++GO:0102102///homocarnosine synthase activity GO:0035499///carnosine biosynthetic process 107242 107242 'AI837181' mRNA 307 285 258 11.76 10.81 10.5 13.11 14.01 15.3 11.02333333 14.14 392 409 443 283.3333333 414.6666667 1.49E-04 0.540324647 GO:0005575///cellular_component GO:0008150///biological_process 107250 107250 'Kazald1' mRNA 2780 2872 2872 115.32 117.53 126.35 53.89 55.91 55.83 119.7333333 55.21 1494 1512 1497 2841.333333 1501 1.06E-38 -0.933372042 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix GO:0005520///insulin-like growth factor binding GO:0001503///ossification+++GO:0001558///regulation of cell growth+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization 107260 107260 'Otub1' mRNA 3078 3057 3169 106.75 104.52 116.6 110.77 110.86 106.83 109.29 109.4866667 3670 3585 3425 3101.333333 3560 0.010886181 0.185319259 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019784///NEDD8-specific protease activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0101005///ubiquitinyl hydrolase activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0071347///cellular response to interleukin-1+++GO:1901315///negative regulation of histone H2A K63-linked ubiquitination+++GO:2000780///negative regulation of double-strand break repair 107271 107271 'Yars' mRNA 1491 1613 1510 34.75 37.02 37.34 32.08 30.45 30.77 36.37 31.1 1583 1467 1470 1538 1506.666667 0.686252067 -0.041943695 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004831///tyrosine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006437///tyrosyl-tRNA aminoacylation 107272 107272 'Psat1' mRNA 6755 6669 6448 175.47 170.66 177.73 124.18 117.83 118.28 174.62 120.0966667 5496 5094 5067 6624 5219 1.10E-10 -0.356335305 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++00750///Vitamin B6 metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors" GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004648///O-phospho-L-serine:2-oxoglutarate aminotransferase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding GO:0006564///L-serine biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process 107303348 107303348 'Gm45935' mRNA 53.3 0 0 0.74 0 0 0.23 0.52 0.51 0.246666667 0.42 19.23 42.04 40.98 17.76666667 34.08333333 0.784669114 0.955452681 00310///Lysine degradation GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding GO:0034968///histone lysine methylation 107305 107305 'Vps37c' mRNA 1054 1035 1004 22.66 21.88 22.57 22.88 25.43 23.68 22.37 23.99666667 1231 1328 1250 1031 1269.666667 0.001273711 0.289512799 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0048306///calcium-dependent protein binding GO:0006612///protein targeting to membrane+++GO:0006623///protein targeting to vacuole+++GO:0015031///protein transport+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 107321 107321 'Lpxn' mRNA 51 69 49 1.73 2.31 1.75 30.77 30.01 30.2 1.93 30.32666667 1041 991 989 56.33333333 1007 1.99E-161 4.150223398 GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043542///endothelial cell migration+++GO:0050859///negative regulation of B cell receptor signaling pathway" 107328 107328 'Trpt1' mRNA 455.83 499.83 419.26 20.72 22.34 20.95 11.27 12.06 11.48 21.33666667 11.60333333 263.94 281.37 279.63 458.3066667 274.98 2.81E-08 -0.747136332 GO:0000922///spindle pole+++GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule GO:0000215///tRNA 2'-phosphotransferase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity "GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0007283///spermatogenesis+++GO:0008033///tRNA processing+++GO:0009615///response to virus+++GO:0019827///stem cell population maintenance+++GO:0045859///regulation of protein kinase activity+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000384///negative regulation of ectoderm development" 107338 107338 'Gbf1' mRNA 2208 2199 2091 18.2 17.83 18.29 15.74 15.36 14.75 18.10666667 15.28333333 2199 2097 1995 2166 2097 0.493343332 -0.058500871 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0031252///cell leading edge "GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0002263///cell activation involved in immune response+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006895///Golgi to endosome transport+++GO:0007030///Golgi organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0030593///neutrophil chemotaxis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0034067///protein localization to Golgi apparatus+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048205///COPI coating of Golgi vesicle+++GO:0061162///establishment of monopolar cell polarity+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0090166///Golgi disassembly+++GO:0097111///endoplasmic reticulum-Golgi intermediate compartment organization+++GO:0098586///cellular response to virus+++GO:1903409///reactive oxygen species biosynthetic process+++GO:1903420///protein localization to endoplasmic reticulum tubular network+++GO:2000008///regulation of protein localization to cell surface" 107351 107351 'Kank1' mRNA 2321 2315 2336 22.31 21.85 23.77 9.34 9.33 9.16 22.64333333 9.276666667 1116 1098 1068 2324 1094 1.17E-48 -1.099908904 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane GO:0008013///beta-catenin binding GO:0008283///cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0030036///actin cytoskeleton organization+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030336///negative regulation of cell migration+++GO:0030837///negative regulation of actin filament polymerization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090303///positive regulation of wound healing+++GO:0090521///glomerular visceral epithelial cell migration+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1900028///negative regulation of ruffle assembly+++GO:2000114///regulation of establishment of cell polarity+++GO:2000393///negative regulation of lamellipodium morphogenesis 107358 107358 'Tm9sf3' mRNA 1726 1816 1517 14.89 15.41 13.89 14.68 12.99 14.49 14.73 14.05333333 1959 1693 1873 1686.333333 1841.666667 0.181576753 0.117168353 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0072657///protein localization to membrane 107368 107368 'Pdzd8' mRNA 876 805 892 6.54 5.9 7.06 6.09 5.75 5.66 6.5 5.833333333 940 868 846 857.6666667 884.6666667 0.843681506 0.029908144 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044233///Mitochondria-associated ER Membrane GO:0003674///molecular_function+++GO:0008289///lipid binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis+++GO:0035556///intracellular signal transduction+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering 107371 107371 'Exoc6' mRNA 406 442 420 7.34 7.67 7.98 7.62 6.57 6.57 7.663333333 6.92 486 406 403 422.6666667 431.6666667 0.923958299 0.01685752 GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0090543///Flemming body GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0015031///protein transport+++GO:0030218///erythrocyte differentiation+++GO:0090522///vesicle tethering involved in exocytosis 107373 107373 'Fam111a' mRNA 46 36 58 0.79 0.61 1.06 9.89 10.49 10.11 0.82 10.16333333 663 687 655 46.66666667 668.3333333 8.76E-99 3.825346316 GO:0000785///chromatin+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016540///protein autoprocessing+++GO:0031297///replication fork processing+++GO:0045071///negative regulation of viral genome replication 107375 107375 'Slc25a45' mRNA 204 224 183 4.73 5.62 4.62 11.05 11.55 11.98 4.99 11.52666667 535 540 555 203.6666667 543.3333333 3.50E-26 1.406736228 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015227///acyl carnitine transmembrane transporter activity GO:0006844///acyl carnitine transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:1902616///acyl carnitine transmembrane transport 107392 107392 'Brms1' mRNA 816 719 767 35.43 30.75 35.13 37.95 37 35.72 33.77 36.89 1003 957 914 767.3333333 958 0.003053992 0.306954911 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0070822///Sin3-type complex GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0051059///NF-kappaB binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0009987///cellular process+++GO:0016575///histone deacetylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0042981///regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090312///positive regulation of protein deacetylation+++GO:2000210///positive regulation of anoikis" 107435 107435 'Hat1' mRNA 711 766 761 26.47 28.12 30.05 32.3 33.23 32.05 28.21333333 32.52666667 997 1001 957 746 985 8.73E-05 0.388182112 04613///Neutrophil extracellular trap formation+++05034///Alcoholism "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex" "GO:0004402///histone acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding" GO:0006325///chromatin organization+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006348///chromatin silencing at telomere+++GO:0007584///response to nutrient+++GO:0016573///histone acetylation+++GO:0031509///telomeric heterochromatin assembly+++GO:0043967///histone H4 acetylation 107448 107448 'Unc5a' mRNA 34 13.57 9.79 0.44 0.14 0.09 0.14 0.11 0.04 0.223333333 0.096666667 13.01 9 3 19.12 8.336666667 0.178003696 -1.16662414 04360///Axon guidance GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0032589///neuron projection membrane+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045121///membrane raft GO:0005042///netrin receptor activity GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0031175///neuron projection development+++GO:0033564///anterior/posterior axon guidance+++GO:0038007///netrin-activated signaling pathway 107449 107449 'Unc5b' mRNA 27 28 13 0.24 0.25 0.13 0.34 0.45 0.46 0.206666667 0.416666667 43 55 56 22.66666667 51.33333333 0.008314334 1.181318347 04360///Axon guidance GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0005042///netrin receptor activity+++GO:0005515///protein binding GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0033564///anterior/posterior axon guidance+++GO:0038007///netrin-activated signaling pathway+++GO:0043524///negative regulation of neuron apoptotic process+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 107476 107476 'Acaca' mRNA 896 851 870 4.93 4.6 5.08 3.97 3.47 3.96 4.87 3.8 827 702 800 872.3333333 776.3333333 0.099964989 -0.181876729 00061///Fatty acid biosynthesis+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++01212///Fatty acid metabolism+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++04936///Alcoholic liver disease GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003989///acetyl-CoA carboxylase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0009374///biotin binding+++GO:0016874///ligase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001894///tissue homeostasis+++GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0008152///metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0019538///protein metabolic process+++GO:0051289///protein homotetramerization+++GO:0055088///lipid homeostasis+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:2001295///malonyl-CoA biosynthetic process 107477 107477 'Guca1b' mRNA 9 8 11 0.08 0.21 0.19 0.12 0.16 0.03 0.16 0.103333333 7 12 4 9.333333333 7.666666667 0.800081803 -0.298369065 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0008048///calcium sensitive guanylate cyclase activator activity+++GO:0030249///guanylate cyclase regulator activity+++GO:0046872///metal ion binding GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0031282///regulation of guanylate cyclase activity+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0050896///response to stimulus 107503 107503 'Atf5' mRNA 640 669 268 21.35 21.99 9.48 8.1 7.58 7.86 17.60666667 7.846666667 279 255 262 525.6666667 265.3333333 0.015083346 -0.979905146 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034399///nuclear periphery" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0031072///heat shock protein binding+++GO:0035497///cAMP response element binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0007623///circadian rhythm+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0021891///olfactory bulb interneuron development+++GO:0021930///cerebellar granule cell precursor proliferation+++GO:0021988///olfactory lobe development+++GO:0035264///multicellular organism growth+++GO:0038066///p38MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046605///regulation of centrosome cycle+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0050768///negative regulation of neurogenesis+++GO:0051726///regulation of cell cycle+++GO:0097284///hepatocyte apoptotic process+++GO:1902750///negative regulation of cell cycle G2/M phase transition" 107508 107508 'Eprs' mRNA 2666 2802 2679 28.93 29.91 30.76 28.24 29.37 28.03 29.86666667 28.54666667 2985 3032 2881 2715.666667 2966 0.115507631 0.115454478 00860///Porphyrin metabolism+++00970///Aminoacyl-tRNA biosynthesis+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0097452///GAIT complex+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004818///glutamate-tRNA ligase activity+++GO:0004827///proline-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016874///ligase activity+++GO:0035613///RNA stem-loop binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006424///glutamyl-tRNA aminoacylation+++GO:0006433///prolyl-tRNA aminoacylation+++GO:0008152///metabolic process+++GO:0017148///negative regulation of translation+++GO:0032869///cellular response to insulin stimulus+++GO:0043039///tRNA aminoacylation+++GO:0071346///cellular response to interferon-gamma+++GO:0140212///regulation of long-chain fatty acid import into cell 107513 107513 'Ssr1' mRNA 3973 4005.1 4391.01 34.45 33.23 41.48 58.35 56.88 56.53 36.38666667 57.25333333 6820 6522.65 6395 4123.036667 6579.216667 1.15E-19 0.658617052 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 107515 107515 'Lgr4' mRNA 1962 1803 2069 20.71 18.71 23.16 12.51 12.78 12.05 20.86 12.44666667 1365 1362 1273 1944.666667 1333.333333 1.14E-09 -0.559823237 04310///Wnt signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0016500///protein-hormone receptor activity+++GO:0048495///Roundabout binding "GO:0001649///osteoblast differentiation+++GO:0001818///negative regulation of cytokine production+++GO:0001942///hair follicle development+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007411///axon guidance+++GO:0007623///circadian rhythm+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030539///male genitalia development+++GO:0032922///circadian regulation of gene expression+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0035239///tube morphogenesis+++GO:0036335///intestinal stem cell homeostasis+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046849///bone remodeling+++GO:0048511///rhythmic process+++GO:0048565///digestive tract development+++GO:0050673///epithelial cell proliferation+++GO:0050919///negative chemotaxis+++GO:0061290///canonical Wnt signaling pathway involved in metanephric kidney development+++GO:0072202///cell differentiation involved in metanephros development+++GO:0072224///metanephric glomerulus development+++GO:0072282///metanephric nephron tubule morphogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis" 107522 107522 'Ece2' mRNA 0 11 3 0 0.19 0.06 0 0.56 0.42 0.083333333 0.326666667 0 36 27 4.666666667 21 0.432339694 2.197441218 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0003824///catalytic activity+++GO:0004222///metalloendopeptidase activity+++GO:0008168///methyltransferase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008152///metabolic process+++GO:0010002///cardioblast differentiation+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0032259///methylation 107526 107526 'Gimap4' mRNA 37 47 55 1.32 1.47 2.1 4.57 5.7 4.74 1.63 5.003333333 150 174 155 46.33333333 159.6666667 2.15E-11 1.7701707 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding 107527 107527 'Il1rl2' mRNA 6 16 13 0.08 0.21 0.19 1.43 1.36 1.64 0.16 1.476666667 124 115 138 11.66666667 125.6666667 1.05E-19 3.417012539 04060///Cytokine-cytokine receptor interaction GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003953///NAD+ nucleosidase activity+++GO:0004896///cytokine receptor activity+++GO:0004908///interleukin-1 receptor activity+++GO:0004909///interleukin-1, type I, activating receptor activity+++GO:0016787///hydrolase activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045087///innate immune response+++GO:0045582///positive regulation of T cell differentiation+++GO:0050727///regulation of inflammatory response+++GO:0070498///interleukin-1-mediated signaling pathway 107528 107528 'Magee1' mRNA 1171 1282 1138 17.74 19.11 18.29 11.9 11.81 11.34 18.38 11.68333333 904 876 834 1197 871.3333333 8.82E-08 -0.46894665 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 107566 107566 'Arl2bp' mRNA 1151 1169 463 32.24 31.97 14.09 14.83 17.25 16.68 26.1 16.25333333 594 689 665 927.6666667 649.3333333 0.273544553 -0.505207232 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030496///midbody+++GO:0042995///cell projection GO:0003713///transcription coactivator activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity "GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050790///regulation of catalytic activity+++GO:0051457///maintenance of protein location in nucleus" 107568 107568 'Wwp1' mRNA 809 777 659 6.63 6.27 5.73 9.73 9.27 9.67 6.21 9.556666667 1366 1272 1315 748.3333333 1317.666667 5.69E-20 0.807010575 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030217///T cell differentiation+++GO:0030324///lung development+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated" 107569 107569 'Nt5c3' mRNA 956 1038 1040 33.51 35.77 38.59 35.2 37.22 33.16 35.95666667 35.19333333 1119 1156 1022 1011.333333 1099 0.351986837 0.106885945 00240///Pyrimidine metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0008253///5'-nucleotidase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation+++GO:0046050///UMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process+++GO:0046085///adenosine metabolic process+++GO:0051607///defense response to virus 107581 107581 'Col16a1' mRNA 2621 2668 2607 32.06 31.88 33.96 31.97 30.62 30.3 32.63333333 30.96333333 3052 2903 2806 2632 2920.333333 0.053773431 0.137342674 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005588///collagen type V trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0033622///integrin activation+++GO:0033627///cell adhesion mediated by integrin+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0071230///cellular response to amino acid stimulus 107586 107586 'Ovol2' mRNA 103 119 107 5.43 5.96 6.02 3.6 4.51 3.82 5.803333333 3.976666667 78 100 85 109.6666667 87.66666667 0.246728808 -0.332328267 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001755///neural crest cell migration+++GO:0001842///neural fold formation+++GO:0001947///heart looping+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0009913///epidermal cell differentiation+++GO:0009953///dorsal/ventral pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010837///regulation of keratinocyte proliferation+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0051726///regulation of cell cycle+++GO:0060214///endocardium formation+++GO:0060347///heart trabecula formation+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0060716///labyrinthine layer blood vessel development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2000647///negative regulation of stem cell proliferation" 107587 107587 'Osr2' mRNA 50 75 46 1.64 2.46 1.63 0.35 0.63 0.4 1.91 0.46 12 22 14 57 16 5.38E-05 -1.833871583 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001823///mesonephros development+++GO:0002062///chondrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0009790///embryo development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0033687///osteoblast proliferation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042476///odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048793///pronephros development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060322///head development+++GO:0060349///bone morphogenesis+++GO:0061029///eyelid development in camera-type eye+++GO:0072498///embryonic skeletal joint development+++GO:2000543///positive regulation of gastrulation" 107589 107589 'Mylk' mRNA 180 166 173 1.89 1.76 1.7 2.19 1.68 1.69 1.783333333 1.853333333 237 181 170 173 196 0.491798603 0.164892382 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0032154///cleavage furrow+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004687///myosin light chain kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006939///smooth muscle contraction+++GO:0014820///tonic smooth muscle contraction+++GO:0016310///phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0032060///bleb assembly+++GO:0035690///cellular response to drug+++GO:0035865///cellular response to potassium ion+++GO:0051928///positive regulation of calcium ion transport+++GO:0060414///aorta smooth muscle tissue morphogenesis+++GO:0071277///cellular response to calcium ion+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071476///cellular hypotonic response+++GO:0090303///positive regulation of wound healing 107605 107605 'Rdh1' mRNA 66.73 58.39 48.91 0.93 0.8 0.72 0.6 0.44 0.4 0.816666667 0.48 49.35 35.52 31.83 58.01 38.9 0.139294136 -0.59143455 00830///Retinol metabolism GO:0005789///endoplasmic reticulum membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:1900054///positive regulation of retinoic acid biosynthetic process 107607 107607 'Nod1' mRNA 411 393 375 5.32 5.01 5.21 6.02 5.56 6.38 5.18 5.986666667 540 488 544 393 524 0.001154042 0.403434768 04621///NOD-like receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0045335///phagocytic vesicle+++GO:0046658///anchored component of plasma membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0050700///CARD domain binding GO:0002221///pattern recognition receptor signaling pathway+++GO:0002376///immune system process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006952///defense response+++GO:0010942///positive regulation of cell death+++GO:0016045///detection of bacterium+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0035556///intracellular signal transduction+++GO:0042742///defense response to bacterium+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071225///cellular response to muramyl dipeptide+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904417///positive regulation of xenophagy 107650 107650 'Pi4kb' mRNA 1034 1051.37 690.83 14.87 14.79 10.66 8.85 9.73 10.04 13.44 9.54 703.28 765.91 770.71 925.4 746.6333333 0.021382936 -0.312493396 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030867///rough endoplasmic reticulum membrane GO:0000166///nucleotide binding+++GO:0004430///1-phosphatidylinositol 4-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0071889///14-3-3 protein binding GO:0016310///phosphorylation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling 107652 107652 'Uap1' mRNA 482 457 343 8.59 8.06 6.53 8.77 8.38 9.13 7.726666667 8.76 551 513 546 427.3333333 536.6666667 0.019327281 0.322086982 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003977///UDP-N-acetylglucosamine diphosphorylase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0052630///UDP-N-acetylgalactosamine diphosphorylase activity+++GO:0070569///uridylyltransferase activity GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process 107684 107684 'Coro2a' mRNA 42 47 22 0.56 0.64 0.32 2.48 1.96 2.38 0.506666667 2.273333333 206 161 191 37 186 1.60E-17 2.325482783 GO:0005903///brush border+++GO:0017053///transcriptional repressor complex GO:0003779///actin binding+++GO:0051015///actin filament binding 107686 107686 'Snrpd2' mRNA 976 956 1103 164.78 157.95 195.26 164.48 182.21 175.35 172.6633333 174.0133333 1114 1205 1149 1011.666667 1156 0.128079411 0.177409715 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 107701 107701 'Sf3b4' mRNA 2267 2404 2059 75.36 78.77 72.62 79.17 80.44 74.25 75.58333333 77.95333333 2737 2714 2484 2243.333333 2645 0.001666151 0.228019126 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0071005///U2-type precatalytic spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:1990935///splicing factor binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 107702 107702 'Rnh1' mRNA 4309 4550 4337 150.59 156.61 160.62 261.6 260.49 259.71 155.94 260.6 8659 8390 8306 4398.666667 8451.666667 3.60E-66 0.93002772 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032311///angiogenin-PRI complex GO:0008428///ribonuclease inhibitor activity GO:0043086///negative regulation of catalytic activity+++GO:0045765///regulation of angiogenesis 107723 107723 'Slc12a6' mRNA 2318.62 2285.58 2221.41 20.22 19.5 20.46 14.57 12.88 14.33 20.06 13.92666667 1941.42 1689.01 1849.34 2275.203333 1826.59 7.29E-06 -0.329521589 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008519///ammonium transmembrane transporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006884///cell volume homeostasis+++GO:0007268///chemical synaptic transmission+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071805///potassium ion transmembrane transport+++GO:0140157///ammonium import across plasma membrane+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 107732 107732 'Mrpl10' mRNA 1134 1180.91 1286 39.23 40.46 47.55 49.18 46.2 50.19 42.41333333 48.52333333 1632 1494 1610 1200.303333 1578.666667 5.66E-05 0.380150778 03010///Ribosome GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit+++GO:1990904///ribonucleoprotein complex GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0042254///ribosome biogenesis 107733 107733 'Mrpl41' mRNA 780 776 772 17.98 17.62 18.88 19.02 18.39 19.46 18.16 18.95666667 949 896 940 776 928.3333333 0.012233323 0.246043884 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:1990904///ribonucleoprotein complex GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle 107734 107734 'Mrpl30' mRNA 844 878 911 75.05 77.39 84.53 81.63 91.19 79.54 78.99 84.12 1070 1125 997 877.6666667 1064 0.011691258 0.264477034 03010///Ribosome GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003674///molecular_function+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 107746 107746 'Rapgef1' mRNA 652 714 568 5.91 6.44 5.54 4.98 4.66 4.48 5.963333333 4.706666667 633 577 545 644.6666667 585 0.244590207 -0.149212556 04015///Rap1 signaling pathway+++04510///Focal adhesion+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0030670///phagocytic vesicle membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0001568///blood vessel development+++GO:0007264///small GTPase mediated signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0032486///Rap protein signal transduction+++GO:0038180///nerve growth factor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0046328///regulation of JNK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0061028///establishment of endothelial barrier+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090630///activation of GTPase activity+++GO:0098609///cell-cell adhesion+++GO:1901888///regulation of cell junction assembly+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000178///negative regulation of neural precursor cell proliferation 107747 107747 'Aldh1l1' mRNA 472 441 440 8.39 7.69 8.27 8.86 8.62 8.89 8.116666667 8.79 574 547 562 451 561 0.012037414 0.30285255 00670///One carbon pool by folate GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0003824///catalytic activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0005515///protein binding+++GO:0016155///formyltetrahydrofolate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016742///hydroxymethyl-, formyl- and related transferase activity+++GO:0033721///aldehyde dehydrogenase (NADP+) activity+++GO:0044877///protein-containing complex binding" GO:0006730///one-carbon metabolic process+++GO:0009058///biosynthetic process+++GO:0009258///10-formyltetrahydrofolate catabolic process 107751 107751 'Prrxl1' mRNA 4 10 3 0.07 0.19 0.1 0.04 0 0.02 0.12 0.02 2 0 1 5.666666667 1 0.136640367 -2.505462757 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0009593///detection of chemical stimulus+++GO:0016048///detection of temperature stimulus+++GO:0021516///dorsal spinal cord development+++GO:0021559///trigeminal nerve development+++GO:0030182///neuron differentiation+++GO:0050954///sensory perception of mechanical stimulus" 107753 107753 'Lgals2' mRNA 2 2 2 0.26 0.26 0.28 0 0.47 0.12 0.266666667 0.196666667 0 4 1 2 1.666666667 0.914197237 -0.258591754 GO:0005737///cytoplasm GO:0016936///galactoside binding+++GO:0030246///carbohydrate binding 107765 107765 'Ankrd1' mRNA 0 0 1 0 0 0.03 8.52 7.91 8.45 0.01 8.293333333 299 271 287 0.333333333 285.6666667 3.72E-15 9.626639315 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030016///myofibril+++GO:0031674///I band+++GO:0032991///protein-containing complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031432///titin binding+++GO:0042826///histone deacetylase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070412///R-SMAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010976///positive regulation of neuron projection development+++GO:0035690///cellular response to drug+++GO:0035914///skeletal muscle cell differentiation+++GO:0035994///response to muscle stretch+++GO:0043065///positive regulation of apoptotic process+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050714///positive regulation of protein secretion+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0070528///protein kinase C signaling+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2000279///negative regulation of DNA biosynthetic process" 107766 107766 'Haao' mRNA 4 12 9 0.15 0.19 0.32 1.09 1.57 1.13 0.22 1.263333333 29 41 28 8.333333333 32.66666667 0.001405687 1.961952294 00380///Tryptophan metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031966///mitochondrial membrane "GO:0000334///3-hydroxyanthranilate 3,4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0019825///oxygen binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006569///tryptophan catabolic process+++GO:0009435///NAD biosynthetic process+++GO:0010043///response to zinc ion+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0019805///quinolinate biosynthetic process+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0043420///anthranilate metabolic process+++GO:0046686///response to cadmium ion+++GO:0046874///quinolinate metabolic process+++GO:0070050///neuron cellular homeostasis 107767 107767 'Scamp1' mRNA 3956 4098 4066 59.76 60.91 65.15 37.93 37.15 38.28 61.94 37.78666667 2892 2760 2831 4040 2827.666667 1.14E-16 -0.527813581 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0032588///trans-Golgi network membrane+++GO:0042589///zymogen granule membrane+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0015031///protein transport 107769 107769 'Tm6sf1' mRNA 132.21 142.52 103.58 3.96 4.53 3.6 6.24 4.75 6.49 4.03 5.826666667 226.7 163.86 222.02 126.1033333 204.1933333 0.001478773 0.687794083 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 107770 107770 'Tm6sf2' mRNA 39 23 33 1.6 0.93 1.44 0.39 0.81 0.85 1.323333333 0.683333333 11 22 23 31.66666667 18.66666667 0.183358119 -0.772795066 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0042802///identical protein binding GO:0019216///regulation of lipid metabolic process+++GO:0055088///lipid homeostasis 107771 107771 'Bmyc' mRNA 824 842 785 65.49 66.29 66.21 48.93 51.24 45.35 65.99666667 48.50666667 705 719 631 817 685 0.012624775 -0.265282246 GO:0005634///nucleus+++GO:0005819///spindle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation" 107815 107815 'Scml2' mRNA 18 25 19 0.19 0.26 0.22 0.23 0.2 0.28 0.223333333 0.236666667 25 21 28 20.66666667 24.66666667 0.722185492 0.245501232 GO:0000785///chromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0031519///PcG protein complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0009653///anatomical structure morphogenesis+++GO:0034613///cellular protein localization+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated" 107817 107817 'Jmjd6' mRNA 879 855 726 30.48 29.19 26.71 18.28 22.89 22.58 28.79333333 21.25 605 740 723 820 689.3333333 0.036830981 -0.257079289 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0032451///demethylase activity+++GO:0032452///histone demethylase activity+++GO:0033746///histone demethylase activity (H3-R2 specific)+++GO:0033749///histone demethylase activity (H4-R3 specific)+++GO:0035515///oxidative RNA demethylase activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0070815///peptidyl-lysine 5-dioxygenase activity+++GO:0106140///P-TEFb complex binding "GO:0001568///blood vessel development+++GO:0001822///kidney development+++GO:0002040///sprouting angiogenesis+++GO:0006325///chromatin organization+++GO:0006397///mRNA processing+++GO:0006482///protein demethylation+++GO:0006909///phagocytosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008380///RNA splicing+++GO:0018395///peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0033077///T cell differentiation in thymus+++GO:0035513///oxidative RNA demethylation+++GO:0042116///macrophage activation+++GO:0043277///apoptotic cell clearance+++GO:0043654///recognition of apoptotic cell+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048821///erythrocyte development+++GO:0051260///protein homooligomerization+++GO:0060041///retina development in camera-type eye+++GO:0070078///histone H3-R2 demethylation+++GO:0070079///histone H4-R3 demethylation" 107823 107823 'Nsd2' mRNA 645 640 531 4.25 4.14 3.65 6.17 5.32 6.45 4.013333333 5.98 1034 873 1039 605.3333333 982 5.38E-11 0.688418 00310///Lysine degradation+++05202///Transcriptional misregulation in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003149///membranous septum morphogenesis+++GO:0003289///atrial septum primum morphogenesis+++GO:0003290///atrial septum secundum morphogenesis+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010452///histone H3-K36 methylation+++GO:0032259///methylation+++GO:0034770///histone H4-K20 methylation+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0060348///bone development+++GO:0070201///regulation of establishment of protein localization+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining" 107829 107829 'Thoc5' mRNA 364 343 318 9.15 8.46 8.47 11.26 11.25 11.27 8.693333333 11.26 516 503 500 341.6666667 506.3333333 7.62E-06 0.557004326 03013///Nucleocytoplasmic transport "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm" GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015459///potassium channel regulator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0000902///cell morphogenesis+++GO:0001824///blastocyst development+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0006468///protein phosphorylation+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0010793///regulation of mRNA export from nucleus+++GO:0016310///phosphorylation+++GO:0017145///stem cell division+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0030224///monocyte differentiation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0035556///intracellular signal transduction+++GO:0045650///negative regulation of macrophage differentiation+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport+++GO:0060215///primitive hemopoiesis+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:2000035///regulation of stem cell division" 107831 107831 'Adgrb1' mRNA 124 85 20 1.14 0.77 0.2 0.07 0.15 0.11 0.703333333 0.11 8 18 12 76.33333333 12.66666667 5.64E-06 -2.572131938 04115///p53 signaling pathway GO:0001891///phagocytic cup+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0001530///lipopolysaccharide binding+++GO:0001786///phosphatidylserine binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding "GO:0002376///immune system process+++GO:0006909///phagocytosis+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007517///muscle organ development+++GO:0010596///negative regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0031397///negative regulation of protein ubiquitination+++GO:0042177///negative regulation of protein catabolic process+++GO:0043277///apoptotic cell clearance+++GO:0043652///engulfment of apoptotic cell+++GO:0045087///innate immune response+++GO:0048167///regulation of synaptic plasticity+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051963///regulation of synapse assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1901741///positive regulation of myoblast fusion+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process" 107868 107868 'Usp9y' mRNA 0 0 2 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016477///cell migration+++GO:0016579///protein deubiquitination 107869 107869 'Cth' mRNA 51 36 45 1.63 1.14 1.53 1.53 1.08 1.24 1.433333333 1.283333333 55 38 43 44 45.33333333 0.961321955 0.026185284 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++00450///Selenocompound metabolism+++01230///Biosynthesis of amino acids" GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004121///cystathionine beta-lyase activity+++GO:0004123///cystathionine gamma-lyase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0016829///lyase activity+++GO:0016846///carbon-sulfur lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding+++GO:0044540///L-cystine L-cysteine-lyase (deaminating)+++GO:0080146///L-cysteine desulfhydrase activity GO:0006749///glutathione metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0008652///cellular amino acid biosynthetic process+++GO:0018272///protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0019344///cysteine biosynthetic process+++GO:0019346///transsulfuration+++GO:0030308///negative regulation of cell growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044524///protein sulfhydration+++GO:0050667///homocysteine metabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051289///protein homotetramerization+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:1904831///positive regulation of aortic smooth muscle cell differentiation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2001234///negative regulation of apoptotic signaling pathway 107885 107885 'Mthfs' mRNA 307.67 362.25 275.34 28.38 33.04 27.01 39.54 42.63 34.55 29.47666667 38.90666667 495.73 518.46 417.05 315.0866667 477.08 4.92E-05 0.591428303 00670///One carbon pool by folate GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0003690///double-stranded DNA binding+++GO:0005524///ATP binding+++GO:0005542///folic acid binding+++GO:0016874///ligase activity+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding "GO:0006353///DNA-templated transcription, termination+++GO:0006393///termination of mitochondrial transcription+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0032392///DNA geometric change+++GO:0035999///tetrahydrofolate interconversion+++GO:0046653///tetrahydrofolate metabolic process" 107895 107895 'Mgat5' mRNA 399 368 369 4.44 4.03 4.11 3.31 2.77 3 4.193333333 3.026666667 346 272 319 378.6666667 312.3333333 0.058788141 -0.291366009 00510///N-Glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043204///perikaryon "GO:0004864///protein phosphatase inhibitor activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030144///alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity+++GO:0030145///manganese ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030335///positive regulation of cell migration+++GO:1903614///negative regulation of protein tyrosine phosphatase activity+++GO:1904894///positive regulation of STAT cascade 107932 107932 'Chd4' mRNA 2510.04 2594 2403 20.41 20.75 20.66 21.33 20.26 21.73 20.60666667 21.10666667 3018 2803 2976 2502.346667 2932.333333 8.06E-04 0.217261252 05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016581///NuRD complex+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0000166///nucleotide binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001221///transcription cofactor binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0032508///DNA duplex unwinding+++GO:0072553///terminal button organization 107934 107934 'Celsr3' mRNA 393 332 327 1.73 1.44 1.53 0.23 0.17 0.27 1.566666667 0.223333333 58 43 69 350.6666667 56.66666667 5.36E-38 -2.641245147 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding GO:0001764///neuron migration+++GO:0001932///regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007413///axonal fasciculation+++GO:0032880///regulation of protein localization+++GO:0036514///dopaminergic neuron axon guidance+++GO:0036515///serotonergic neuron axon guidance+++GO:0060271///cilium assembly+++GO:0098609///cell-cell adhesion+++GO:1904938///planar cell polarity pathway involved in axon guidance 107939 107939 'Pom121' mRNA 352.29 325.29 304.66 3.69 3.31 3.43 3.74 3.69 3.88 3.476666667 3.77 410.76 394.83 417.41 327.4133333 407.6666667 0.029956308 0.305225109 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006999///nuclear pore organization+++GO:0015031///protein transport+++GO:0051028///mRNA transport 107951 107951 'Cdk9' mRNA 429.18 373.36 411.02 5.74 5.27 6.18 6.42 6.57 6.21 5.73 6.4 518.19 529.45 481.31 404.52 509.65 0.0183038 0.319911163 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008023///transcription elongation factor complex+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0016592///mediator complex+++GO:0016605///PML body+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070691///P-TEFb complex GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017069///snRNA binding+++GO:0019901///protein kinase binding+++GO:0097322///7SK snRNA binding GO:0006281///DNA repair+++GO:0006282///regulation of DNA repair+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0016310///phosphorylation+++GO:0031056///regulation of histone modification+++GO:0031297///replication fork processing+++GO:0033129///positive regulation of histone phosphorylation+++GO:0042493///response to drug+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051147///regulation of muscle cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071345///cellular response to cytokine stimulus+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1903839///positive regulation of mRNA 3'-UTR binding+++GO:2001168///positive regulation of histone H2B ubiquitination 107971 107971 'Frs3' mRNA 82 65 64 2.12 1.59 1.75 0.78 0.99 0.93 1.82 0.9 34 45 41 70.33333333 40 0.019911392 -0.822335191 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005104///fibroblast growth factor receptor binding+++GO:0042802///identical protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008543///fibroblast growth factor receptor signaling pathway 107975 107975 'Pacs1' mRNA 1242 1368 469 15.57 16.81 6.34 5.14 6.02 6.09 12.90666667 5.75 465 533 540 1026.333333 512.6666667 0.037689995 -0.989829349 GO:0005794///Golgi apparatus+++GO:0030137///COPI-coated vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0044325///ion channel binding GO:0032092///positive regulation of protein binding+++GO:0034067///protein localization to Golgi apparatus+++GO:0034613///cellular protein localization+++GO:0072659///protein localization to plasma membrane 107976 107976 'Babam2' mRNA 485 527 490 22.63 24.22 24.22 24.55 22.46 23.45 23.69 23.48666667 605 540 559 500.6666667 568 0.182051038 0.169734498 03440///Homologous recombination GO:0000152///nuclear ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070531///BRCA1-A complex+++GO:0070552///BRISC complex GO:0005164///tumor necrosis factor receptor binding+++GO:0031593///polyubiquitin modification-dependent protein binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010212///response to ionizing radiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045739///positive regulation of DNA repair+++GO:0051301///cell division+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint 107986 107986 'Ddb2' mRNA 427.37 449.25 386.5 13.24 14.04 12.82 9.54 8.8 9.64 13.36666667 9.326666667 351.3 318.52 324.79 421.04 331.5366667 0.008776396 -0.356172617 03420///Nucleotide excision repair+++04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05161///Hepatitis B+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030054///cell junction+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0044877///protein-containing complex binding GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006290///pyrimidine dimer repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination+++GO:0035518///histone H2A monoubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070914///UV-damage excision repair 107993 107993 'Bfsp2' mRNA 11 11 22 0.47 0.49 1 0.27 0.32 0.63 0.653333333 0.406666667 7 8 15 14.66666667 10 0.519717509 -0.578875409 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane GO:0005198///structural molecule activity+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding GO:0007010///cytoskeleton organization+++GO:0007601///visual perception+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045109///intermediate filament organization+++GO:0048469///cell maturation+++GO:0050896///response to stimulus+++GO:0070307///lens fiber cell development 107995 107995 'Cdc20' mRNA 89 79 74 2.88 2.52 2.54 24.26 22.57 21.55 2.646666667 22.79333333 862 783 741 80.66666667 795.3333333 2.74E-110 3.290224409 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0010997///anaphase-promoting complex binding+++GO:0019899///enzyme binding+++GO:0042826///histone deacetylase binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990757///ubiquitin ligase activator activity GO:0000089///mitotic metaphase+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031915///positive regulation of synaptic plasticity+++GO:0040020///regulation of meiotic nuclear division+++GO:0050773///regulation of dendrite development+++GO:0051301///cell division+++GO:0090129///positive regulation of synapse maturation+++GO:0090307///mitotic spindle assembly+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:1905786///positive regulation of anaphase-promoting complex-dependent catabolic process 107999 107999 'Gtpbp6' mRNA 547.18 562.45 263.42 20.86 20.62 11.3 9.67 13.24 12.31 17.59333333 11.74 286.96 374.25 352.84 457.6833333 338.0166667 0.056657564 -0.432803322 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding GO:0008150///biological_process 108000 108000 'Cenpf' mRNA 52.67 38.86 36.37 0.25 0.18 0.19 1.33 1.24 1.29 0.206666667 1.286666667 322.83 294.53 304.44 42.63333333 307.2666667 4.07E-40 2.857957484 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005930///axoneme+++GO:0016363///nuclear matrix+++GO:0030496///midbody+++GO:0036064///ciliary basal body+++GO:0045120///pronucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097539///ciliary transition fiber" GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0070840///dynein complex binding "GO:0000278///mitotic cell cycle+++GO:0001822///kidney development+++GO:0002724///regulation of T cell cytokine production+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0007059///chromosome segregation+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0015031///protein transport+++GO:0016202///regulation of striated muscle tissue development+++GO:0021591///ventricular system development+++GO:0030885///regulation of myeloid dendritic cell activation+++GO:0032386///regulation of intracellular transport+++GO:0032886///regulation of microtubule-based process+++GO:0043066///negative regulation of apoptotic process+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048866///stem cell fate specification+++GO:0050863///regulation of T cell activation+++GO:0051310///metaphase plate congression+++GO:0070201///regulation of establishment of protein localization" 108011 108011 'Ap4e1' mRNA 381.56 390.14 394.42 3.32 3.36 3.66 3.8 3.47 3.81 3.446666667 3.693333333 494.18 449.05 488.42 388.7066667 477.2166667 0.033131667 0.283406905 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030124///AP-4 adaptor complex GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 108012 108012 'Ap1s2' mRNA 250 287 293 5.45 6.35 6.79 21.84 18.24 21.53 6.196666667 20.53666667 1176 981 1112 276.6666667 1089.666667 9.70E-64 1.962868366 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030121///AP-1 adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0006886///intracellular protein transport+++GO:0008542///visual learning+++GO:0015031///protein transport+++GO:0016182///synaptic vesicle budding from endosome+++GO:0016192///vesicle-mediated transport+++GO:0036465///synaptic vesicle recycling+++GO:0045444///fat cell differentiation+++GO:0050885///neuromuscular process controlling balance+++GO:0060612///adipose tissue development 108013 108013 'Celf4' mRNA 31 33 49 0.42 0.45 0.7 0.64 0.51 0.55 0.523333333 0.566666667 55 43 46 37.66666667 48 0.493108046 0.326541019 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0036002///pre-mRNA binding+++GO:0042835///BRE binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:1902866///regulation of retina development in camera-type eye" 108014 108014 'Srsf9' mRNA 276 276 205 14.68 14.5 11.57 15.86 17.12 16.35 13.58333333 16.44333333 342 360 341 252.3333333 347.6666667 0.004193261 0.45632376 03040///Spliceosome+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0019904///protein domain specific binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0009636///response to toxic substance+++GO:0043279///response to alkaloid+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 108015 108015 'Chrnb4' mRNA 3.9 1.02 8.01 0.06 0.02 0.13 0.04 0.01 0.01 0.07 0.02 3.1 1 0.65 4.31 1.583333333 0.397884036 -1.644697985 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098981///cholinergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0044877///protein-containing complex binding+++GO:1901363///heterocyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001508///action potential+++GO:0006811///ion transport+++GO:0006939///smooth muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007626///locomotory behavior+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035095///behavioral response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060084///synaptic transmission involved in micturition" 108017 108017 'Fxyd4' mRNA 11 15 5 0.39 0.49 0.18 0.36 0.21 0.12 0.353333333 0.23 6 7 4 10.33333333 5.666666667 0.412209551 -0.86076633 04960///Aldosterone-regulated sodium reabsorption GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005267///potassium channel activity+++GO:0017080///sodium channel regulator activity+++GO:0051117///ATPase binding+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0043269///regulation of ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:2000649///regulation of sodium ion transmembrane transporter activity 108030 108030 'Lin7a' mRNA 887 953 770 7.9 8.32 7.27 1.97 2.58 2.04 7.83 2.196666667 255 325 256 870 278.6666667 2.76E-38 -1.648990612 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030658///transport vesicle membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0098793///presynapse+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0097016///L27 domain binding GO:0006887///exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0015031///protein transport+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0048489///synaptic vesicle transport+++GO:0048839///inner ear development+++GO:1903361///protein localization to basolateral plasma membrane 108037 108037 'Shmt2' mRNA 807 753 775 19.67 18.07 20.04 18.48 19.69 19.95 19.26 19.37333333 872 907 912 778.3333333 897 0.069810495 0.192741393 "00260///Glycine, serine and threonine metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00670///One carbon pool by folate+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors+++01523///Antifolate resistance" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0042645///mitochondrial nucleoid+++GO:0070552///BRISC complex "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003682///chromatin binding+++GO:0003824///catalytic activity+++GO:0004372///glycine hydroxymethyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008732///L-allo-threonine aldolase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0050897///cobalt ion binding+++GO:0070905///serine binding" GO:0002082///regulation of oxidative phosphorylation+++GO:0006544///glycine metabolic process+++GO:0006545///glycine biosynthetic process+++GO:0006563///L-serine metabolic process+++GO:0006564///L-serine biosynthetic process+++GO:0006565///L-serine catabolic process+++GO:0006730///one-carbon metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009113///purine nucleobase biosynthetic process+++GO:0017148///negative regulation of translation+++GO:0019264///glycine biosynthetic process from serine+++GO:0034340///response to type I interferon+++GO:0035999///tetrahydrofolate interconversion+++GO:0046653///tetrahydrofolate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0051262///protein tetramerization+++GO:0051289///protein homotetramerization+++GO:0070129///regulation of mitochondrial translation+++GO:0070536///protein K63-linked deubiquitination+++GO:1903715///regulation of aerobic respiration 108043 108043 'Chrnb3' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding "GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:2000300///regulation of synaptic vesicle exocytosis" 108052 108052 'Slc14a1' mRNA 1744 1928 1764 25.66 27.82 27.51 8.25 9.05 9.34 26.99666667 8.88 649 694 709 1812 684 1.70E-60 -1.416161219 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005372///water transmembrane transporter activity+++GO:0015204///urea transmembrane transporter activity+++GO:0015265///urea channel activity GO:0006833///water transport+++GO:0015840///urea transport+++GO:0071918///urea transmembrane transport 108058 108058 'Camk2d' mRNA 2752 2824 1834 30.77 30.84 21.96 19.37 26.98 24.52 27.85666667 23.62333333 1934 2692 2454 2470 2360 0.854195024 -0.064422229 04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04114///Oocyte meiosis+++04217///Necroptosis+++04261///Adrenergic signaling in cardiomyocytes+++04310///Wnt signaling pathway+++04360///Axon guidance+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04934///Cushing syndrome+++04971///Gastric acid secretion+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005954///calcium- and calmodulin-dependent protein kinase complex+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019871///sodium channel inhibitor activity+++GO:0031432///titin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0050998///nitric-oxide synthase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001666///response to hypoxia+++GO:0002028///regulation of sodium ion transport+++GO:0003254///regulation of membrane depolarization+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010649///regulation of cell communication by electrical coupling+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030007///cellular potassium ion homeostasis+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0046777///protein autophosphorylation+++GO:0055119///relaxation of cardiac muscle+++GO:0060048///cardiac muscle contraction+++GO:0060341///regulation of cellular localization+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0086003///cardiac muscle cell contraction+++GO:0098901///regulation of cardiac muscle cell action potential+++GO:1901897///regulation of relaxation of cardiac muscle+++GO:1902306///negative regulation of sodium ion transmembrane transport+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 108062 108062 'Cstf2' mRNA 700 753 661 8.7 9.24 8.65 7.91 7.75 8.76 8.863333333 8.14 710.9 688.65 768.69 704.6666667 722.7466667 0.863090843 0.024935231 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0016604///nuclear body+++GO:0071920///cleavage body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031124///mRNA 3'-end processing+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:1990090///cellular response to nerve growth factor stimulus 108067 108067 'Eif2b3' mRNA 500 500 489 17.99 18.19 18.72 17.85 20.13 18.33 18.3 18.77 566 612 551 496.3333333 576.3333333 0.107641064 0.204333048 05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0032045///guanyl-nucleotide exchange factor complex "GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008135///translation factor activity, RNA binding+++GO:0016779///nucleotidyltransferase activity" GO:0002183///cytoplasmic translational initiation+++GO:0006413///translational initiation+++GO:0009058///biosynthetic process+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0014003///oligodendrocyte development+++GO:0021766///hippocampus development+++GO:0043434///response to peptide hormone+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway 108068 108068 'Grm2' mRNA 73 86 84 1.2 1.39 1.46 0.09 0.04 0.15 1.35 0.093333333 6 3 10 81 6.333333333 3.09E-14 -3.691203605 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++05030///Cocaine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097449///astrocyte projection+++GO:0099055///integral component of postsynaptic membrane GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0001641///group II metabotropic glutamate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005246///calcium channel regulator activity+++GO:0097110///scaffold protein binding "GO:0001662///behavioral fear response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0008344///adult locomotory behavior+++GO:0010467///gene expression+++GO:0014047///glutamate secretion+++GO:0014048///regulation of glutamate secretion+++GO:0014059///regulation of dopamine secretion+++GO:0033554///cellular response to stress+++GO:0035095///behavioral response to nicotine+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042220///response to cocaine+++GO:0043523///regulation of neuron apoptotic process+++GO:0048148///behavioral response to cocaine+++GO:0051896///regulation of protein kinase B signaling+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0090461///glutamate homeostasis+++GO:2001023///regulation of response to drug" 108069 108069 'Grm3' mRNA 8 4 8 0.12 0.05 0.13 0.01 0.01 0.02 0.1 0.013333333 1 1 2 6.666666667 1.333333333 0.102301872 -2.341959132 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++05030///Cocaine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane+++GO:0048786///presynaptic active zone+++GO:0097449///astrocyte projection+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0001641///group II metabotropic glutamate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005246///calcium channel regulator activity+++GO:0097110///scaffold protein binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0010467///gene expression+++GO:0019233///sensory perception of pain+++GO:0033554///cellular response to stress+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051930///regulation of sensory perception of pain+++GO:0051966///regulation of synaptic transmission, glutamatergic" 108073 108073 'Grm7' mRNA 22 39 23 0.37 0.51 0.37 0.26 0.29 0.22 0.416666667 0.256666667 22 21 16 28 19.66666667 0.395314613 -0.515441165 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043198///dendritic shaft+++GO:0043235///receptor complex+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048786///presynaptic active zone+++GO:0048787///presynaptic active zone membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0001642///group III metabotropic glutamate receptor activity+++GO:0003723///RNA binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0008066///glutamate receptor activity+++GO:0010855///adenylate cyclase inhibitor activity+++GO:0016595///glutamate binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity+++GO:0048306///calcium-dependent protein binding+++GO:0070905///serine binding "GO:0001661///conditioned taste aversion+++GO:0001662///behavioral fear response+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007605///sensory perception of sound+++GO:0007613///memory+++GO:0007614///short-term memory+++GO:0008306///associative learning+++GO:0014050///negative regulation of glutamate secretion+++GO:0019226///transmission of nerve impulse+++GO:0030534///adult behavior+++GO:0031279///regulation of cyclase activity+++GO:0033555///multicellular organismal response to stress+++GO:0043086///negative regulation of catalytic activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050877///nervous system process+++GO:0050896///response to stimulus+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0061564///axon development+++GO:0070085///glycosylation+++GO:0070588///calcium ion transmembrane transport+++GO:1901214///regulation of neuron death+++GO:2000300///regulation of synaptic vesicle exocytosis" 108075 108075 'Ltbp4' mRNA 1249 1157 933 13.46 12.08 10.67 4.97 5.08 5.02 12.07 5.023333333 537 548 533 1113 539.3333333 1.96E-23 -1.052034099 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0050431///transforming growth factor beta binding GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0030162///regulation of proteolysis+++GO:0046879///hormone secretion+++GO:0048251///elastic fiber assembly 108077 108077 'Skiv2l' mRNA 1899 1808 1758 26.08 24.43 25.67 25.77 23.59 23.93 25.39333333 24.43 2155 1935 1932 1821.666667 2007.333333 0.115151934 0.127601598 03018///RNA degradation GO:0055087///Ski complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0006401///RNA catabolic process+++GO:0070478///nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay" 108078 108078 'Olr1' mRNA 4 9 15 0.07 0.14 0.29 1.95 2.06 2.15 0.166666667 2.053333333 140 140 151 9.333333333 143.6666667 6.69E-24 3.926227685 03320///PPAR signaling pathway+++04145///Phagosome+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0045121///membrane raft GO:0005041///low-density lipoprotein particle receptor activity+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0008219///cell death+++GO:0010629///negative regulation of gene expression+++GO:0042157///lipoprotein metabolic process 108079 108079 'Prkaa2' mRNA 451 455 386 2.9 2.88 2.63 2.27 2.13 2.43 2.803333333 2.276666667 408 372 420 430.6666667 400 0.451378052 -0.116078336 04068///FoxO signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016324///apical plasma membrane+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body "GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030674///protein binding, bridging+++GO:0035174///histone serine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047322///[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity+++GO:0050405///[acetyl-CoA carboxylase] kinase activity" GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006914///autophagy+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010629///negative regulation of gene expression+++GO:0014823///response to activity+++GO:0014850///response to muscle activity+++GO:0016055///Wnt signaling pathway+++GO:0016126///sterol biosynthetic process+++GO:0016241///regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0019216///regulation of lipid metabolic process+++GO:0031000///response to caffeine+++GO:0031669///cellular response to nutrient levels+++GO:0032007///negative regulation of TOR signaling+++GO:0034599///cellular response to oxidative stress+++GO:0035404///histone-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0042149///cellular response to glucose starvation+++GO:0042593///glucose homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0045821///positive regulation of glycolytic process+++GO:0048511///rhythmic process+++GO:0055089///fatty acid homeostasis+++GO:0062028///regulation of stress granule assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071277///cellular response to calcium ion+++GO:0071333///cellular response to glucose stimulus+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0097009///energy homeostasis+++GO:1903829///positive regulation of cellular protein localization+++GO:1904428///negative regulation of tubulin deacetylation+++GO:2000758///positive regulation of peptidyl-lysine acetylation 108083 108083 'Pip4k2b' mRNA 329.53 364.92 280.83 1.55 1.61 1.35 0.95 1.03 1.07 1.503333333 1.016666667 232.25 257.73 253.06 325.0933333 247.68 0.014328836 -0.397732748 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04810///Regulation of actin cytoskeleton GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016309///1-phosphatidylinositol-5-phosphate 4-kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity "GO:0010506///regulation of autophagy+++GO:0016310///phosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0061909///autophagosome-lysosome fusion+++GO:0090217///negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:1902635///1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process+++GO:2000786///positive regulation of autophagosome assembly" 108086 108086 'Rnf216' mRNA 1156 1176 1216 13.78 13.74 15.29 12.45 12.14 12.94 14.27 12.51 1215 1149 1220 1182.666667 1194.666667 0.998591786 8.75E-04 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098843///postsynaptic endocytic zone+++GO:0098978///glutamatergic synapse GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0032648///regulation of interferon-beta production+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050691///regulation of defense response to virus by host+++GO:0070936///protein K48-linked ubiquitination+++GO:0099546///protein catabolic process, modulating synaptic transmission" 108089 108089 'Rnf144a' mRNA 59 71 39 0.61 0.74 0.43 0.89 0.86 1.3 0.593333333 1.016666667 98 92 138 56.33333333 109.3333333 0.002334266 0.954616518 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 108096 108096 'Slco1a5' mRNA 673.51 714 673 14.42 15.04 15.28 15.65 14.34 15.57 14.91333333 15.18666667 839 755.57 806.99 686.8366667 800.52 0.049715612 0.208097407 04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0015718///monocarboxylic acid transport+++GO:0015721///bile acid and bile salt transport+++GO:0031100///animal organ regeneration+++GO:0043252///sodium-independent organic anion transport+++GO:0050892///intestinal absorption+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport 108097 108097 'Prkab2' mRNA 475 534 507 5.03 5.54 5.68 3.79 4.33 3.54 5.416666667 3.886666667 414 461 376 505.3333333 417 0.040701662 -0.288698861 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016324///apical plasma membrane+++GO:0031588///nucleotide-activated protein kinase complex GO:0004679///AMP-activated protein kinase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0080090///regulation of primary metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis 108098 108098 'Med21' mRNA 707 713 719 62.27 62.26 67.2 77.04 77.15 78.77 63.91 77.65333333 1001 976 988 713 988.3333333 1.40E-06 0.458413065 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0001824///blastocyst development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II 108099 108099 'Prkag2' mRNA 719 736 563 10.97 10.73 8.88 7.5 8.55 7.99 10.19333333 8.013333333 647 667 635 672.6666667 649.6666667 0.708985955 -0.056811507 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031588///nucleotide-activated protein kinase complex GO:0000166///nucleotide binding+++GO:0004679///AMP-activated protein kinase activity+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0005524///ATP binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0008607///phosphorylase kinase regulator activity+++GO:0016208///AMP binding+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0032559///adenyl ribonucleotide binding+++GO:0043531///ADP binding GO:0005977///glycogen metabolic process+++GO:0006110///regulation of glycolytic process+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:0045860///positive regulation of protein kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0071900///regulation of protein serine/threonine kinase activity+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 108100 108100 'Baiap2' mRNA 611 576 574 12.35 11.3 12.98 30.07 25.29 31.02 12.21 28.79333333 1595 1330 1613 587 1512.666667 2.62E-44 1.352639143 04520///Adherens junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection "GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030141///secretory granule+++GO:0030175///filopodium+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044306///neuron projection terminus+++GO:0060076///excitatory synapse+++GO:0061845///neuron projection branch point+++GO:0061846///dendritic spine cytoplasm+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol" GO:0001221///transcription cofactor binding+++GO:0005515///protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding+++GO:0097110///scaffold protein binding "GO:0007009///plasma membrane organization+++GO:0007266///Rho protein signal transduction+++GO:0007420///brain development+++GO:0008360///regulation of cell shape+++GO:0009617///response to bacterium+++GO:0010976///positive regulation of neuron projection development+++GO:0016358///dendrite development+++GO:0030182///neuron differentiation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035418///protein localization to synapse+++GO:0048167///regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051017///actin filament bundle assembly+++GO:0051764///actin crosslink formation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0099564///modification of synaptic structure, modulating synaptic transmission+++GO:1905232///cellular response to L-glutamate+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2000463///positive regulation of excitatory postsynaptic potential" 108101 108101 'Fermt3' mRNA 149.17 144.17 156.74 3.2 3.05 3.57 37.3 37.23 33.8 3.273333333 36.11 1999.06 1948.63 1754.37 150.0266667 1900.686667 8.73E-240 3.653719176 04611///Platelet activation GO:0002102///podosome+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0042995///cell projection GO:0005178///integrin binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0033622///integrin activation+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0070527///platelet aggregation 108105 108105 'B3gnt5' mRNA 0 1 2 0 0.01 0.02 0.27 0.25 0.14 0.01 0.22 26 25 13 1 21.33333333 1.03E-04 4.393982897 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008457///beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047256///lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0030148///sphingolipid biosynthetic process 108112 108112 'Eif4ebp3' mRNA 107 75 99 5.76 3.99 5.65 5.86 5.43 6.35 5.133333333 5.88 125 113 131 93.66666667 123 0.175248433 0.377617191 GO:0005737///cytoplasm GO:0008190///eukaryotic initiation factor 4E binding GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0045947///negative regulation of translational initiation 108114 108114 'Slc22a7' mRNA 23 45 30 0.65 1.26 0.9 0.3 0.33 0.2 0.936666667 0.276666667 12 13 8 32.66666667 11 0.006634535 -1.578074245 04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0035634///response to stilbenoid+++GO:0055085///transmembrane transport 108115 108115 'Slco4a1' mRNA 57 111 86 1.03 2.09 1.67 1.97 2.03 1.95 1.596666667 1.983333333 120 119 114 84.66666667 117.6666667 0.128194965 0.46372628 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0042403///thyroid hormone metabolic process+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport 108116 108116 'Slco3a1' mRNA 1722 1823 1470 28.28 29.86 24.96 7.35 7.52 7.5 27.7 7.456666667 546 524 552 1671.666667 540.6666667 4.70E-76 -1.636716207 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0035673///oligopeptide transmembrane transporter activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006811///ion transport+++GO:0006857///oligopeptide transport+++GO:0015711///organic anion transport+++GO:0015732///prostaglandin transport+++GO:0043252///sodium-independent organic anion transport+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0055085///transmembrane transport 108121 108121 'U2af1' mRNA 1597 1403 1136 116.27 100.79 87.25 124.43 137.45 130.09 101.4366667 130.6566667 1951 2116 1982 1378.666667 2016.333333 2.68E-08 0.542665985 03040///Spliceosome+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome+++GO:0089701///U2AF GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0046872///metal ion binding+++GO:0050733///RS domain binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 108123 108123 'Napg' mRNA 564 673 601 8.77 10.28 9.97 8.83 8.43 8.7 9.673333333 8.653333333 655 612 619 612.6666667 628.6666667 0.863090843 0.025414723 GO:0005739///mitochondrion+++GO:0005774///vacuolar membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0005483///soluble NSF attachment protein activity+++GO:0019905///syntaxin binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 108124 108124 'Napa' mRNA 4613 5001 5016 150.85 159.22 172.26 153.3 161.06 151.99 160.7766667 155.45 5456 5595 5232 4876.666667 5427.666667 0.062543426 0.141158969 04721///Synaptic vesicle cycle GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0043209///myelin sheath+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005483///soluble NSF attachment protein activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding+++GO:0044877///protein-containing complex binding "GO:0006886///intracellular protein transport+++GO:0007420///brain development+++GO:0010807///regulation of synaptic vesicle priming+++GO:0015031///protein transport+++GO:0016082///synaptic vesicle priming+++GO:0016192///vesicle-mediated transport+++GO:0030182///neuron differentiation+++GO:0032781///positive regulation of ATPase activity+++GO:0032984///protein-containing complex disassembly+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035494///SNARE complex disassembly+++GO:0045176///apical protein localization" 108138 108138 'Xrcc4' mRNA 263 290 305 9.81 10.65 12.01 6.48 7.18 7.88 10.82333333 7.18 199 214 233 286 215.3333333 0.017114454 -0.422921791 03450///Non-homologous end-joining "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005958///DNA-dependent protein kinase-DNA ligase 4 complex+++GO:0032807///DNA ligase IV complex+++GO:0035861///site of double-strand break+++GO:0070419///nonhomologous end joining complex+++GO:0070522///ERCC4-ERCC1 complex" GO:0003677///DNA binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070975///FHA domain binding+++GO:1990599///3' overhang single-stranded DNA endodeoxyribonuclease activity GO:0001701///in utero embryonic development+++GO:0002328///pro-B cell differentiation+++GO:0006266///DNA ligation+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007417///central nervous system development+++GO:0010165///response to X-ray+++GO:0010212///response to ionizing radiation+++GO:0010332///response to gamma radiation+++GO:0033077///T cell differentiation in thymus+++GO:0033151///V(D)J recombination+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045190///isotype switching+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0051103///DNA ligation involved in DNA repair+++GO:0051351///positive regulation of ligase activity+++GO:0061819///telomeric DNA-containing double minutes formation+++GO:0071285///cellular response to lithium ion+++GO:1905765///negative regulation of protection from non-homologous end joining at telomere+++GO:1905782///positive regulation of phosphatidylserine exposure on apoptotic cell surface+++GO:1990166///protein localization to site of double-strand break 108143 108143 'Taf9' mRNA 1236.33 1261.97 1118.48 61.84 62.32 59.36 79.83 76.6 81.98 61.17333333 79.47 1831.75 1714.69 1819.49 1205.593333 1788.643333 4.73E-14 0.558926903 03022///Basal transcription factors GO:0000124///SAGA complex+++GO:0000125///PCAF complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0070761///pre-snoRNP complex+++GO:0071339///MLL1 complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0033613///activating transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0051117///ATPase binding+++GO:0070742///C2H2 zinc finger domain binding "GO:0000492///box C/D snoRNP assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043966///histone H3 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0070555///response to interleukin-1" 108147 108147 'Atic' mRNA 363 372 190 7.72 7.79 4.29 8.13 6.11 7.12 6.6 7.12 440 323 373 308.3333333 378.6666667 0.188424129 0.295024097 00230///Purine metabolism+++00670///One carbon pool by folate+++01523///Antifolate resistance GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003824///catalytic activity+++GO:0003937///IMP cyclohydrolase activity+++GO:0004643///phosphoribosylaminoimidazolecarboxamide formyltransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity GO:0003360///brainstem development+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0008152///metabolic process+++GO:0009116///nucleoside metabolic process+++GO:0009259///ribonucleotide metabolic process+++GO:0010035///response to inorganic substance+++GO:0021549///cerebellum development+++GO:0021987///cerebral cortex development+++GO:0031100///animal organ regeneration+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0046452///dihydrofolate metabolic process+++GO:0046654///tetrahydrofolate biosynthetic process+++GO:0097294///'de novo' XMP biosynthetic process+++GO:0098761///cellular response to interleukin-7 108148 108148 'Galnt2' mRNA 1646 1528 1174 21.59 19.71 16.33 19.67 22.34 20.88 19.21 20.96333333 1726 1915 1775 1449.333333 1805.333333 0.002561289 0.312037713 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005796///Golgi lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0016266///O-glycan processing+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine+++GO:0051604///protein maturation 108150 108150 'Galnt7' mRNA 1043 1006 955 12.92 12.26 12.55 9.29 8.18 9.29 12.57666667 8.92 863 743 836 1001.333333 814 0.001286891 -0.310855412 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation 108151 108151 'Sema3d' mRNA 150 192 149 1.22 1.53 1.28 1.77 1.58 2.08 1.343333333 1.81 251 219 286 163.6666667 252 0.001442438 0.613271196 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 108153 108153 'Adamts7' mRNA 138 131 137 1.17 1.22 1.41 0.82 0.66 0.95 1.266666667 0.81 107 92 115 135.3333333 104.6666667 0.122218446 -0.384314392 GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0002062///chondrocyte differentiation+++GO:0006029///proteoglycan metabolic process+++GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0043931///ossification involved in bone maturation+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071773///cellular response to BMP stimulus 108154 108154 'Adamts6' mRNA 49 52 37 0.45 0.42 0.34 0.47 0.34 0.37 0.403333333 0.393333333 68 50 56 46 58 0.42604285 0.325679022 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0006508///proteolysis+++GO:0007507///heart development+++GO:0030198///extracellular matrix organization+++GO:0035904///aorta development+++GO:0060976///coronary vasculature development 108155 108155 'Ogt' mRNA 11193 11776 10661 111.67 115.57 112.91 71.88 70.13 70.69 113.3833333 70.9 8286 7910 7887 11210 8027.666667 1.70E-24 -0.492757445 00514///Other types of O-glycan biosynthesis+++04931///Insulin resistance GO:0000123///histone acetyltransferase complex+++GO:0000791///euchromatin+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0017122///protein N-acetylglucosaminyltransferase complex+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0042588///zymogen granule+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body "GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008080///N-acetyltransferase activity+++GO:0008134///transcription factor binding+++GO:0008289///lipid binding+++GO:0016262///protein N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019904///protein domain specific binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0048029///monosaccharide binding+++GO:0097363///protein O-GlcNAc transferase activity" GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006041///glucosamine metabolic process+++GO:0006110///regulation of glycolytic process+++GO:0006111///regulation of gluconeogenesis+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0006915///apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0016485///protein processing+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035020///regulation of Rac protein signal transduction+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045793///positive regulation of cell size+++GO:0045862///positive regulation of proteolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048312///intracellular distribution of mitochondria+++GO:0048511///rhythmic process+++GO:0060548///negative regulation of cell death+++GO:0061087///positive regulation of histone H3-K27 methylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071333///cellular response to glucose stimulus+++GO:0080182///histone H3-K4 trimethylation+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900038///negative regulation of cellular response to hypoxia+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process 108156 108156 'Mthfd1' mRNA 892 902 806 14.1 14.12 13.74 11.97 12.71 12.96 13.98666667 12.54666667 858 888 888 866.6666667 878 0.943432254 0.009066467 00670///One carbon pool by folate+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0004486///methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity+++GO:0004487///methylenetetrahydrofolate dehydrogenase (NAD+) activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0016491///oxidoreductase activity+++GO:0016787///hydrolase activity+++GO:0016874///ligase activity GO:0000105///histidine biosynthetic process+++GO:0001780///neutrophil homeostasis+++GO:0001843///neural tube closure+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006555///methionine metabolic process+++GO:0006730///one-carbon metabolic process+++GO:0007507///heart development+++GO:0008152///metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009069///serine family amino acid metabolic process+++GO:0009070///serine family amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0019346///transsulfuration+++GO:0035999///tetrahydrofolate interconversion+++GO:0061053///somite development 108159 108159 'Ubxn8' mRNA 1148.06 1087.48 1166.55 14.96 14.24 16.8 11.83 11.45 11.68 15.33333333 11.65333333 929.11 876.87 871.84 1134.03 892.6066667 1.68E-04 -0.360005977 04141///Protein processing in endoplasmic reticulum GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003674///molecular_function GO:0030433///ubiquitin-dependent ERAD pathway 108160 108160 'Fam50a' mRNA 809 878 802 34.89 37.41 36.83 42.33 46.32 42.55 36.37666667 43.73333333 1125 1202 1095 829.6666667 1140.666667 1.51E-06 0.448773173 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0006325///chromatin organization+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing 108161 108161 'Fam50b' mRNA 5 0 0 0.25 0 0 0.04 0.09 0 0.083333333 0.043333333 1 2 0 1.666666667 1 0.839445158 -0.719277454 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030496///midbody+++GO:0045171///intercellular bridge GO:0006325///chromatin organization 108167321 108167321 'Gm10479' mRNA 3.86 3.97 2.3 0.39 0.29 0.18 0.27 0.13 0.38 0.286666667 0.26 2.88 1.9 4.78 3.376666667 3.186666667 0.920226552 -0.198529333 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 108167387 108167387 'LOC108167387' mRNA 0 1 0 0 0.11 0 0.43 0.2 0 0.036666667 0.21 4.42 2 0 0.333333333 2.14 0.425852635 2.457214861 108167412 108167412 'Gm45975' mRNA 3 5 4 0.06 0.1 0.08 0.02 0.07 0.07 0.08 0.053333333 1 4 4 4 3 0.817847257 -0.417888094 108167415 108167415 'Gm45978' mRNA 0 2.51 2.38 0 0.06 0.06 0.18 0.11 0.2 0.04 0.163333333 8.06 4.71 8.71 1.63 7.16 0.122307355 2.298452113 108167437 108167437 'Gm44812' mRNA 0 2 5 0 0.03 0.04 0.01 0.01 0 0.023333333 0.006666667 2 1 0 2.333333333 1 0.629093149 -1.279967586 108167466 108167466 'Gm45618' mRNA 1 0 1 0.05 0 0.05 0.12 0 0 0.033333333 0.04 3 0 0 0.666666667 1 0.888377162 0.525753426 GO:0005882///intermediate filament+++GO:0045095///keratin filament 108167548 108167548 'Gm45855' mRNA 691.53 824.21 599.45 25.93 30.47 23.84 33.82 41.33 40.61 26.74666667 38.58666667 1036.4 1235.82 1203.88 705.0633333 1158.7 6.09E-10 0.711729464 108167553 108167553 'LOC108167553' mRNA 273.67 313.36 305.13 1.37 1.54 1.62 1.43 1.25 1.48 1.51 1.386666667 330.64 281.89 330.78 297.3866667 314.4366667 0.751409522 0.064928385 108167560 108167560 'Gm46058' mRNA 34 42 37 0.89 1.03 0.99 0.51 0.59 0.51 0.97 0.536666667 25 25 31 37.66666667 27 0.319352469 -0.491062282 108167565 108167565 'Gm17149' mRNA 225.18 226.49 251.84 1.01 1 1.2 2.35 2.52 2.44 1.07 2.436666667 602.47 631.53 605.53 234.5033333 613.1766667 1.81E-25 1.374958058 108167594 108167594 'LOC108167594' mRNA 8 9 6 2.73 3.13 2.19 1.52 2.84 1.91 2.683333333 2.09 5 9 6 7.666666667 6.666666667 0.863090843 -0.202806852 108167670 108167670 'Gm17415' mRNA 1.25 4.16 6.68 0.1 0.32 0.55 0.48 0.14 0.2 0.323333333 0.273333333 7.15 2.02 2.92 4.03 4.03 0.987839851 -0.041366521 108167700 108167700 'Gm46139' mRNA 145.69 126.07 106.26 1.34 1.14 1.04 0.45 0.56 0.41 1.173333333 0.473333333 56.04 68.41 50.03 126.0066667 58.16 3.78E-05 -1.122036399 108167705 108167705 'Gm46142' mRNA 6.93 6.56 7.8 1.36 1.29 1.62 0.63 1.16 1.13 1.423333333 0.973333333 3.62 6.5 6.31 7.096666667 5.476666667 0.800369356 -0.351638458 108167848 108167848 'Gm12258' mRNA 493.07 482.71 453 6.43 6.19 6.27 3.5 3.38 3.49 6.296666667 3.456666667 310 294.76 299.77 476.26 301.51 1.33E-07 -0.67243471 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 108167871 108167871 'Gm11703' mRNA 151.11 169.88 171.83 27.13 30.55 32.76 33.53 34.44 36.59 30.14666667 34.85333333 212.17 211.3 222.57 164.2733333 215.3466667 0.052011502 0.380442098 108167874 108167874 'Gm12586' mRNA 68.07 74.32 52.38 1.25 1.34 1.02 0.54 0.18 0.33 1.203333333 0.35 33.73 11.17 20 64.92333333 21.63333333 2.09E-04 -1.612367954 108167877 108167877 'Gm11954' mRNA 9.51 2.74 6.02 1.22 0.35 0.82 0.54 0.46 0 0.796666667 0.333333333 4.8 3.99 0 6.09 2.93 0.411994822 -1.303683188 108167910 108167910 'Gm12712' mRNA 31.44 36.86 18.77 2.34 2.71 1.48 2.31 1.31 1.77 2.176666667 1.796666667 35.66 19.63 26.4 29.02333333 27.23 0.883658516 -0.092470757 108167918 108167918 'Gm46290' mRNA 129.09 144.53 107.28 2.28 2.5 2 5.9 5.55 5.68 2.26 5.71 383.11 353.81 357.06 126.9666667 364.66 2.21E-20 1.515798789 108167925 108167925 'Gm46294' mRNA 19.96 15.8 12.03 0.38 0.3 0.24 0.13 0.1 0.19 0.306666667 0.14 8.03 6 11.02 15.93 8.35 0.276632472 -0.886631438 108167945 108167945 'Gm46305' mRNA 2.14 2.15 1.97 0.05 0.05 0.05 0.13 0.24 0.15 0.05 0.173333333 6.89 12.15 7.53 2.086666667 8.856666667 0.068582404 2.32372259 108167961 108167961 'Gm46319' mRNA 51 41 2 2.74 2.18 0.11 0.19 0.67 0.48 1.676666667 0.446666667 4 14 10 31.33333333 9.333333333 0.048122117 -1.716635542 108167963 108167963 'Gm46320' mRNA 0 4 0 0 0.39 0 0.09 0 0 0.13 0.03 1 0 0 1.333333333 0.333333333 0.653551224 -1.862861599 108167995 108167995 'Gm46345' mRNA 19 34 16 0.1 0.17 0.09 0.18 0.04 0.13 0.12 0.116666667 41 9 27.01 23 25.67 0.863090843 0.147550272 108168034 108168034 'Gm46382' mRNA 59 46 34 0.61 0.47 0.37 0.14 0.18 0.16 0.483333333 0.16 15 20 17 46.33333333 17.33333333 0.002397096 -1.421061867 108168061 108168061 'Gm46399' mRNA 2 5 3 0.66 1.68 1.06 1.48 1.22 1.23 1.133333333 1.31 5 4 4 3.333333333 4.333333333 0.831203155 0.369542205 108168084 108168084 'Gm46415' mRNA 1 3 1 0.19 0.58 0.2 0.17 0.17 0.35 0.323333333 0.23 1 1 2 1.666666667 1.333333333 0.896734841 -0.317669773 03010///Ribosome+++05171///Coronavirus disease - COVID-19 108168101 108168101 'Gm46430' mRNA 811.77 821.94 815.67 9.85 9.79 10.62 6.15 5.86 6.28 10.08666667 6.096666667 576.59 530.67 571.21 816.46 559.49 5.46E-08 -0.558010681 108168114 108168114 'Gm5451' mRNA 0 1.17 1.17 0 0.12 0.13 0.43 0.11 0.12 0.083333333 0.22 4.69 1.15 1.3 0.78 2.38 0.57114016 1.550682922 108168140 108168140 'Gm46442' mRNA 8.01 7.01 3.35 1.13 0.99 0.5 0.87 0.77 0.52 0.873333333 0.72 7 6.01 4.05 6.123333333 5.686666667 0.95317325 -0.082130432 108168145 108168145 'Gm5459' mRNA 35.21 46.07 29.24 0.79 1.02 0.7 0.69 0.86 0.41 0.836666667 0.653333333 35.17 42.84 20.09 36.84 32.7 0.757000519 -0.185593107 108168148 108168148 'Gm5798' mRNA 3 13.65 16 0.12 0.54 0.69 0 0 0 0.45 0 0 0 0 10.88333333 0 4.34E-04 -5.885431282 108168203 108168203 'Gm46487' mRNA 4 1 3 0.06 0.02 0.05 0.11 0.04 0.07 0.043333333 0.073333333 8 3 5 2.666666667 5.333333333 0.523050652 0.974258561 108168211 108168211 'Gm46494' mRNA 1 1 1 0.2 0.2 0.21 0.18 0 0 0.203333333 0.06 1 0 0 1 0.333333333 0.703393499 -1.493333342 108168218 108168218 'Gm5218' mRNA 9.71 5.87 4.39 0.99 0.6 0.48 0.92 0.47 1.07 0.69 0.82 10.27 5.13 11.51 6.656666667 8.97 0.659696017 0.522489902 108168301 108168301 'Gm46562' mRNA 0 1 0 0 0.54 0 0 0 0 0.18 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 108168308 108168308 'Smim34' mRNA 0 1 4 0 0.03 0.11 0 0.07 0 0.046666667 0.023333333 0 3 0 1.666666667 1 0.81985636 -0.774601087 108168333 108168333 'Gm15946' mRNA 5 8 3 0.71 1.13 0.45 0.25 0.13 0.64 0.763333333 0.34 2 1 5 5.333333333 2.666666667 0.517167557 -0.996813732 108168336 108168336 'Gm46592' mRNA 1.07 2.33 1.22 0.01 0.03 0.02 0.01 0.02 0.01 0.02 0.013333333 1.2 2.15 1.42 1.54 1.59 0.999506575 0.001655139 108168358 108168358 'Gm46608' mRNA 179 205 141 2.4 2.7 2 1.59 1.44 1.53 2.366666667 1.52 137 121 127 175 128.3333333 0.040475493 -0.454034687 108168363 108168363 'Gm17669' mRNA 7.61 19.36 15.63 0.83 2.1 1.81 0.91 0.86 1.04 1.58 0.936666667 9.51 8.73 10.5 14.2 9.58 0.496274272 -0.616107827 108168367 108168367 'LOC108168367' mRNA 2.55 3.79 3.17 0.32 0.47 0.42 0.16 0.23 0.46 0.403333333 0.283333333 1.49 2.07 4.01 3.17 2.523333333 0.9183165 -0.202554531 108168373 108168373 'Gm46617' mRNA 46 49 33 1.83 1.92 1.39 1.07 1.06 1 1.713333333 1.043333333 31 30 28 42.66666667 29.66666667 0.24947026 -0.529627215 108168387 108168387 'Gm46629' mRNA 2 2 0 0.03 0.03 0 0.03 0 0 0.02 0.01 2 0 0 1.333333333 0.666666667 0.787589524 -1.002775245 108168395 108168395 'Gm45871' mRNA 321.02 357.81 322.1 5.4 5.92 5.72 2.93 2.84 2.91 5.68 2.893333333 201.54 193.03 191.41 333.6433333 195.3266667 3.47E-07 -0.784765866 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 108168411 108168411 'Gm46650' mRNA 41 51.34 24.03 0.13 0.16 0.08 0.08 0.06 0.16 0.123333333 0.1 30.27 20.45 55.96 38.79 35.56 0.835130155 -0.143163732 108168515 108168515 'Gm21209' mRNA 0 0.2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.066666667 0 GO:0000795///synaptonemal complex GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 108168524 108168524 'Gm20874' mRNA 0 0.2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.066666667 0 GO:0000795///synaptonemal complex GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 108168532 108168532 'Gm21638' mRNA 0 0.2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.066666667 0 GO:0000795///synaptonemal complex GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 108168539 108168539 'Gm21396' mRNA 0.5 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.166666667 0 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 108168540 108168540 'Gm20881' mRNA 0 2 0 0 0.21 0 0 0 0 0.07 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 108168547 108168547 'Gm20894' mRNA 0 0.2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.066666667 0 108168556 108168556 'Gm20859' mRNA 0.25 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.083333333 0 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 108168570 108168570 'Gm21316' mRNA 0.5 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.166666667 0 108168571 108168571 'Gm20862' mRNA 0.5 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.166666667 0 108168626 108168626 'Gm20895' mRNA 0.25 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.083333333 0 108168627 108168627 'Gm21476' mRNA 0.25 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.083333333 0 108168628 108168628 'Gm20893' mRNA 0.25 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.083333333 0 108168648 108168648 'Gm21285' mRNA 0 0 0.17 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.056666667 0 108168650 108168650 'Gm20933' mRNA 0 0 0.17 0 0 0.02 0 0.01 0.01 0.006666667 0.006666667 0 0.06 0.06 0.056666667 0.04 108168651 108168651 'Gm20800' mRNA 0 0 0.17 0 0 0.02 0 0 0.01 0.006666667 0.003333333 0 0 0.06 0.056666667 0.02 108168652 108168652 'Gm20926' mRNA 0 0 0.17 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.056666667 0 108168654 108168654 'Gm21287' mRNA 0 0 0.17 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.056666667 0 108168655 108168655 'Gm20912' mRNA 0 0 0.17 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.056666667 0 108168726 108168726 'LOC108168726' mRNA 760 812 785 40.26 42.49 44.12 2.68 2.13 2.39 42.29 2.4 58 45 50 785.6666667 51 8.16E-127 -3.958663392 108168727 108168727 'Gm46725' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 108168740 108168740 'Gm46731' mRNA 15.61 14.27 17.67 0.69 0.62 0.83 1.08 0.79 0.88 0.713333333 0.916666667 28.28 20.04 22.29 15.85 23.53666667 0.361970689 0.587612064 108168770 108168770 'Gm13653' mRNA 11.46 13.59 11.32 1.72 2.03 1.8 1.55 1.63 1.66 1.85 1.613333333 11.77 12.07 12.17 12.12333333 12.00333333 0.998591786 -0.009312542 108168771 108168771 'Gm50595' mRNA 7 5 1 0.43 0.25 0.07 0.1 0.03 0.05 0.25 0.06 2 1 1 4.333333333 1.333333333 0.341118175 -1.693473203 108168799 108168799 'Gm11686' mRNA 0 4.01 8.85 0 0.13 0.32 0.14 0.12 0.03 0.15 0.096666667 4.84 3.95 1.15 4.286666667 3.313333333 0.75009672 -0.631949584 108168809 108168809 'Gm14279' mRNA 136.37 98.79 99.29 5.41 3.87 4.18 4.96 5.68 5.21 4.486666667 5.283333333 143.64 160.36 145.86 111.4833333 149.9533333 0.091477416 0.418999838 108168824 108168824 'Gm14439' mRNA 17.81 15.97 16.03 1.19 1.05 1.13 0.41 0.71 0.66 1.123333333 0.593333333 7.01 11.98 10.98 16.60333333 9.99 0.315532687 -0.787158927 108168832 108168832 'Gm13981' mRNA 8.69 3.01 4.67 1.79 0.62 1.02 0.47 0.68 1.1 1.143333333 0.75 2.6 3.65 5.83 5.456666667 4.026666667 0.713003394 -0.590325733 108168884 108168884 'Gm37500' mRNA 5 4 2.03 0.22 0.17 0.09 0.19 0.16 0.24 0.16 0.196666667 5.02 4.14 6.03 3.676666667 5.063333333 0.774938988 0.446518641 108168963 108168963 'Zfp978' mRNA 7.94 8.4 7.23 0.17 0.18 0.17 0.19 0.08 0.18 0.173333333 0.15 10.26 4.04 9.45 7.856666667 7.916666667 0.971627704 0.048245571 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 108169021 108169021 'Gm46900' mRNA 3 0 0 0.04 0 0 0.01 0.01 0.01 0.013333333 0.01 1 1 1 1 1 0.998591786 0.01047091 108169040 108169040 'Gm42935' mRNA 1 0 2 0.04 0 0.09 0 0 0.04 0.043333333 0.013333333 0 0 1 1 0.333333333 0.716186228 -1.529828329 108169043 108169043 'Gm46911' mRNA 209.53 196.44 226.15 4.7 4.28 5.37 11.35 13.58 10.7 4.783333333 11.87666667 580.36 674.53 527.74 210.7066667 594.21 2.17E-23 1.483604335 108169053 108169053 'Gm15682' mRNA 76.88 70.86 74.3 9.54 8.75 9.78 9.03 10.02 12.46 9.356666667 10.50333333 83.08 89.57 110.45 74.01333333 94.36666667 0.268963879 0.346561566 108169054 108169054 'Gm46915' mRNA 18 34 13 1.15 2.15 0.88 0.33 0.29 0.35 1.393333333 0.323333333 6 5 6 21.66666667 5.666666667 0.010410208 -1.932393694 108169060 108169060 'Gm50598' mRNA 4 0 7 0.18 0 0.2 0 0 0 0.126666667 0 0 0 0 3.666666667 0 0.080089035 -4.36628838 108169063 108169063 'Gm43247' mRNA 8.82 12.35 7.93 1.63 2.29 1.56 0.71 0.3 0.68 1.826666667 0.563333333 4.34 1.78 3.98 9.7 3.366666667 0.129179799 -1.764862361 108169072 108169072 'Gm6139' mRNA 2184.12 2213.29 1916.53 149.31 149.71 139.03 185.52 239.4 224.57 146.0166667 216.4966667 3110.14 3911.18 3637.58 2104.646667 3552.966667 4.28E-17 0.748694319 108169096 108169096 'Gm46933' mRNA 44.77 28.28 25.72 2.07 1.29 1.26 0.51 0.26 0.55 1.54 0.44 12.67 6.24 13.25 32.92333333 10.72 0.005244675 -1.654980769 108169097 108169097 'Pramel44' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm GO:0003674///molecular_function "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 108169117 108169117 'Gm6272' mRNA 1 0 0 0.81 0 0 0 0 0 0.27 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 108169152 108169152 'Gm46965' mRNA 28 28 14 0.32 0.32 0.17 0.2 0.05 0.16 0.27 0.136666667 20 5 16 23.33333333 13.66666667 0.285165703 -0.778381394 108169197 108169197 'Gm10420' mRNA 35.35 28.82 17.19 2.42 1.95 1.25 0.54 1.35 0.44 1.873333333 0.776666667 9.05 21.96 7.11 27.12 12.70666667 0.098983684 -1.107490023 108645 108645 'Mat2b' mRNA 1995 2310 2168 60.7 69.34 70 54.27 56.56 55.61 66.68 55.48 2041 2078 2020 2157.666667 2046.333333 0.344405728 -0.088497427 00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0048269///methionine adenosyltransferase complex GO:0019899///enzyme binding+++GO:0048270///methionine adenosyltransferase regulator activity GO:0006556///S-adenosylmethionine biosynthetic process+++GO:0006730///one-carbon metabolic process+++GO:0050790///regulation of catalytic activity 108652 108652 'Slc35b3' mRNA 351 453 426 10.75 14.44 13.9 11.14 14.21 13.05 13.03 12.8 403 507 456 410 455.3333333 0.440180168 0.140334553 GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0022857///transmembrane transporter activity+++GO:0046964///3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity GO:0055085///transmembrane transport+++GO:1902559///3'-phospho-5'-adenylyl sulfate transmembrane transport 108653 108653 'Rimklb' mRNA 940.58 844.16 896.81 8.87 8.2 8.6 3.17 3.6 3.09 8.556666667 3.286666667 431.42 412.83 388 893.85 410.75 2.28E-25 -1.135796497 "00250///Alanine, aspartate and glutamate metabolism" GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016879///ligase activity, forming carbon-nitrogen bonds+++GO:0046872///metal ion binding+++GO:0072590///N-acetyl-L-aspartate-L-glutamate ligase activity+++GO:0072591///citrate-L-glutamate ligase activity" GO:0006464///cellular protein modification process 108654 108654 'Fam210a' mRNA 677.68 710.12 634.9 3.67 3.79 3.65 3.53 3.29 3.29 3.703333333 3.37 751.23 683.86 677.06 674.2333333 704.05 0.705271515 0.051713543 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 108655 108655 'Foxp1' mRNA 2737.93 2680.43 2370.92 15.12 15.12 14.74 12.92 11.68 12.65 14.99333333 12.41666667 2338.69 2049.61 2219.25 2596.426667 2202.516667 5.22E-04 -0.247827366 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002329///pre-B cell differentiation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002903///negative regulation of B cell apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0008045///motor neuron axon guidance+++GO:0009790///embryo development+++GO:0010468///regulation of gene expression+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0021517///ventral spinal cord development+++GO:0021756///striatum development+++GO:0030316///osteoclast differentiation+++GO:0030324///lung development+++GO:0030900///forebrain development+++GO:0032496///response to lipopolysaccharide+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032655///regulation of interleukin-12 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032745///positive regulation of interleukin-21 production+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0033574///response to testosterone+++GO:0036035///osteoclast development+++GO:0042116///macrophage activation+++GO:0042117///monocyte activation+++GO:0042118///endothelial cell activation+++GO:0045214///sarcomere organization+++GO:0045655///regulation of monocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048745///smooth muscle tissue development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0055007///cardiac muscle cell differentiation+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0061140///lung secretory cell differentiation+++GO:0061470///T follicular helper cell differentiation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072359///circulatory system development+++GO:0098582///innate vocalization behavior+++GO:0098900///regulation of action potential+++GO:1900424///regulation of defense response to bacterium+++GO:1901249///regulation of lung goblet cell differentiation+++GO:1901250///negative regulation of lung goblet cell differentiation+++GO:1901256///regulation of macrophage colony-stimulating factor production+++GO:1901509///regulation of endothelial tube morphogenesis+++GO:1904637///cellular response to ionomycin+++GO:1905206///positive regulation of hydrogen peroxide-induced cell death+++GO:2000341///regulation of chemokine (C-X-C motif) ligand 2 production" 108657 108657 'Rnpepl1' mRNA 1195 1016 445 19.51 16.85 7.56 9.87 10.53 12.95 14.64 11.11666667 676 708 842 885.3333333 742 0.645282146 -0.246926829 GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis 108660 108660 'Rnf187' mRNA 5558 5789 5150 163.76 168.06 160.97 128.46 175.41 166.15 164.2633333 156.6733333 5012 6681 6274 5499 5989 0.284904771 0.116122459 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination" 108664 108664 'Atp6v1h' mRNA 1878 2106 2041 51.49 56.54 59.19 56.03 60.15 59.51 55.74 58.56333333 2352 2463 2423 2008.333333 2412.666667 0.00198705 0.252387173 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain" "GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0006897///endocytosis+++GO:1902600///proton transmembrane transport 108670 108670 'Epsti1' mRNA 47 49 35 1.44 1.48 1.14 10.53 10.69 12 1.353333333 11.07333333 392 389 428 43.66666667 403 3.82E-58 3.19823671 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 108671 108671 'Dnajc9' mRNA 1244 1280 1266 44.53 45.17 48.07 40.28 44.12 41.24 45.92333333 41.88 1293 1382 1281 1263.333333 1318.666667 0.660627384 0.049971363 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0101031///chaperone complex GO:0031072///heat shock protein binding+++GO:0042393///histone binding+++GO:0051087///chaperone binding GO:0006334///nucleosome assembly+++GO:0032781///positive regulation of ATPase activity 108672 108672 'Zdhhc15' mRNA 91 90 98 1.24 1.17 1.14 0.73 2.03 1.35 1.183333333 1.37 87 125 82 93 98 0.863090843 0.064185446 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030173///integral component of Golgi membrane+++GO:0045202///synapse+++GO:0098794///postsynapse "GO:0008270///zinc ion binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0046872///metal ion binding" GO:0006612///protein targeting to membrane+++GO:0016188///synaptic vesicle maturation+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0045184///establishment of protein localization+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0072657///protein localization to membrane+++GO:1900006///positive regulation of dendrite development 108673 108673 'Ccdc86' mRNA 494 545.99 536.94 9.04 9.83 10.42 15.82 17.33 15.66 9.763333333 16.27 994.94 1064.92 953.89 525.6433333 1004.583333 1.65E-18 0.922762981 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus 108679 108679 'Cops8' mRNA 1799 1927 1771 57.67 60.79 60.31 45.43 46.35 44.03 59.59 45.27 1640 1627 1532 1832.333333 1599.666667 0.007819535 -0.20714604 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008180///COP9 signalosome+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0000338///protein deneddylation+++GO:0006468///protein phosphorylation+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0010387///COP9 signalosome assembly 108682 108682 'Gpt2' mRNA 1264 1377.07 1259.59 16.06 17.29 17.06 25.96 24.53 24.83 16.80333333 25.10666667 2342.01 2154 2170 1300.22 2222.003333 6.97E-26 0.761525689 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids" GO:0005615///extracellular space+++GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0004021///L-alanine:2-oxoglutarate aminotransferase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding GO:0006103///2-oxoglutarate metabolic process+++GO:0009058///biosynthetic process+++GO:0042851///L-alanine metabolic process+++GO:0042853///L-alanine catabolic process+++GO:0045722///positive regulation of gluconeogenesis 108686 108686 'Ccdc88a' mRNA 1032 1027 586 6.67 6.23 3.81 4.14 4.01 4.88 5.57 4.343333333 790 748 894 881.6666667 810.6666667 0.525366194 -0.121056076 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030142///COPI-coated Golgi to ER transport vesicle+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0001965///G-protein alpha-subunit binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031682///G-protein gamma-subunit binding+++GO:0035091///phosphatidylinositol binding+++GO:0042169///SH2 domain binding+++GO:0042803///protein homodimerization activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0043422///protein kinase B binding+++GO:0051959///dynein light intermediate chain binding GO:0001932///regulation of protein phosphorylation+++GO:0006260///DNA replication+++GO:0006275///regulation of DNA replication+++GO:0007264///small GTPase mediated signal transduction+++GO:0007399///nervous system development+++GO:0010975///regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0030030///cell projection organization+++GO:0030032///lamellipodium assembly+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0031929///TOR signaling+++GO:0032147///activation of protein kinase activity+++GO:0032148///activation of protein kinase B activity+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042127///regulation of cell proliferation+++GO:0045724///positive regulation of cilium assembly+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0061024///membrane organization+++GO:0072660///maintenance of protein location in plasma membrane+++GO:1903566///positive regulation of protein localization to cilium 108687 108687 'Edem2' mRNA 1217 1325 1307 30.72 33.57 34.86 40.45 44.6 42.53 33.05 42.52666667 1833 1976 1847 1283 1885.333333 1.62E-10 0.543159511 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0044322///endoplasmic reticulum quality control compartment "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding" "GO:0005975///carbohydrate metabolic process+++GO:0006986///response to unfolded protein+++GO:0036509///trimming of terminal mannose on B branch+++GO:0097466///ubiquitin-dependent glycoprotein ERAD pathway+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway" 108689 108689 'Stn1' mRNA 824 742 804 25.4 22.69 25.98 11.69 11.72 11.64 24.69 11.68333333 458 445 451 790 451.3333333 1.32E-13 -0.821228557 "GO:0000781///chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton+++GO:1990879///CST complex" GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0043047///single-stranded telomeric DNA binding GO:0000723///telomere maintenance+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0016233///telomere capping+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0045740///positive regulation of DNA replication 108699 108699 'Chn1' mRNA 339.42 356.28 345.01 4.86 5.08 5.29 3.25 3.03 2.97 5.076666667 3.083333333 260.24 236.12 228.83 346.9033333 241.73 3.72E-04 -0.535431916 GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046875///ephrin receptor binding GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008045///motor neuron axon guidance+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0050770///regulation of axonogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction 108705 108705 'Pttg1ip' mRNA 7670 8141 7737 181.82 190.14 194.61 195.87 199.41 198.64 188.8566667 197.9733333 9489 9438 9317 7849.333333 9414.666667 5.73E-06 0.250437606 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002039///p53 binding "GO:0006606///protein import into nucleus+++GO:0031398///positive regulation of protein ubiquitination+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1903364///positive regulation of cellular protein catabolic process" 108707 108707 'Fam207a' mRNA 667 850 791 15.14 19.1 18.99 17.39 17.59 17.18 17.74333333 17.38666667 881 865 840 769.3333333 862 0.235605956 0.151201468 "GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0030686///90S preribosome+++GO:0030688///preribosome, small subunit precursor" GO:0003674///molecular_function "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0008150///biological_process" 108723 108723 'Card11' mRNA 12 17 16 0.16 0.22 0.22 0.39 0.33 0.58 0.2 0.433333333 34 28 49 15 37 0.014451084 1.289327591 04064///NF-kappa B signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032449///CBM complex+++GO:0045121///membrane raft GO:0005515///protein binding+++GO:0043621///protein self-association+++GO:0050700///CARD domain binding GO:0002376///immune system process+++GO:0002377///immunoglobulin production+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0030183///B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031295///T cell costimulation+++GO:0032623///interleukin-2 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0038202///TORC1 signaling+++GO:0042100///B cell proliferation+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045061///thymic T cell selection+++GO:0045577///regulation of B cell differentiation+++GO:0045580///regulation of T cell differentiation+++GO:0046649///lymphocyte activation+++GO:0048872///homeostasis of number of cells+++GO:0050776///regulation of immune response+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization 108735 108735 'Sft2d2' mRNA 3755 3973 3431 36.16 37.62 35.05 33.05 33.21 33.76 36.27666667 33.34 3951 3879 3910 3719.666667 3913.333333 0.360039584 0.06358292 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 108737 108737 'Oxsr1' mRNA 366 390 281.04 3.64 3.91 2.85 4.7 3.63 3.97 3.466666667 4.1 507 385 427.03 345.68 439.6766667 0.031271918 0.338605731 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001823///mesonephros development+++GO:0002062///chondrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007231///osmosensory signaling pathway+++GO:0007507///heart development+++GO:0008406///gonad development+++GO:0010628///positive regulation of gene expression+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035556///intracellular signal transduction+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0042474///middle ear morphogenesis+++GO:0042476///odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048389///intermediate mesoderm development+++GO:0048793///pronephros development+++GO:0048863///stem cell differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0071300///cellular response to retinoic acid+++GO:0071476///cellular hypotonic response+++GO:0072075///metanephric mesenchyme development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0072143///mesangial cell development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072166///posterior mesonephric tubule development+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072180///mesonephric duct morphogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0072190///ureter urothelium development+++GO:0072207///metanephric epithelium development+++GO:0072208///metanephric smooth muscle tissue development+++GO:0072234///metanephric nephron tubule development+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072259///metanephric interstitial fibroblast development+++GO:0072268///pattern specification involved in metanephros development+++GO:0072498///embryonic skeletal joint development+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:1990869///cellular response to chemokine+++GO:2000543///positive regulation of gastrulation+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 108755 108755 'Lyrm2' mRNA 729 745 762 32.63 32.9 36.18 29.78 28.93 27.52 33.90333333 28.74333333 764 724.05 683 745.3333333 723.6833333 0.685486661 -0.056192759 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 108760 108760 'Galnt16' mRNA 598 601 606 8.23 8.14 8.84 4.23 3.96 4.41 8.403333333 4.2 354 323 357 601.6666667 344.6666667 9.74E-12 -0.816938641 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine 108767 108767 'Pnrc1' mRNA 4058 4055 891 120.24 118.33 27.65 20.63 23.07 34.03 88.74 25.91 813 880 1283 3001.333333 992 0.02435366 -1.578988355 GO:0005634///nucleus GO:0003674///molecular_function 108797 108797 'Mex3b' mRNA 17 30 24 0.27 0.47 0.41 0.4 0.3 0.52 0.383333333 0.406666667 29 21 36 23.66666667 28.66666667 0.688005548 0.263930655 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0032794///GTPase activating protein binding+++GO:0046872///metal ion binding GO:0022409///positive regulation of cell-cell adhesion+++GO:0043547///positive regulation of GTPase activity+++GO:0050766///positive regulation of phagocytosis+++GO:0072697///protein localization to cell cortex 108800 108800 'Ston2' mRNA 559.96 538.38 457.88 2.99 2.83 2.59 1.93 2.01 2.11 2.803333333 2.016666667 416.19 424.64 441.73 518.74 427.52 0.025744436 -0.287071166 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006897///endocytosis+++GO:0007268///chemical synaptic transmission+++GO:0016192///vesicle-mediated transport+++GO:0030100///regulation of endocytosis+++GO:0036465///synaptic vesicle recycling+++GO:0048488///synaptic vesicle endocytosis 108802 108802 'Calr4' mRNA 10 13 12 0.26 0.29 0.33 0.45 0.16 0.25 0.293333333 0.286666667 18 7 11 11.66666667 12 0.989330003 0.021002928 04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++04612///Antigen processing and presentation+++05142///Chagas disease+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response 108811 108811 'Ccdc122' mRNA 103 107 49 3.92 4.16 2.04 2.19 2.53 2.02 3.373333333 2.246666667 60 69 50 86.33333333 59.66666667 0.153216111 -0.529706383 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 108812 108812 'Flacc1' mRNA 5 8 4 0.1 0.16 0.08 0.18 0.09 0.07 0.113333333 0.113333333 9 5 4 5.666666667 6 0.958517969 0.074452531 GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 108829 108829 'Jmjd1c' mRNA 2507.48 2714.58 2305.8 11.02 11.74 9.87 7.89 7.68 8.18 10.87666667 7.916666667 2290.27 2157.73 2233.57 2509.286667 2227.19 0.009755958 -0.181851604 05202///Transcriptional misregulation in cancer GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0003382///epithelial cell morphogenesis+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008584///male gonad development+++GO:0033169///histone H3-K9 demethylation+++GO:0036098///male germ-line stem cell population maintenance+++GO:0072520///seminiferous tubule development+++GO:0098727///maintenance of cell number+++GO:1990636///reproductive senescence 108832 108832 'Tmem74b' mRNA 173.07 143.23 145.2 3.4 2.99 3.28 0.65 0.76 0.8 3.223333333 0.736666667 62.36 71.37 60.67 153.8333333 64.8 2.06E-07 -1.266514549 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 108837 108837 'Ibtk' mRNA 1161 1268 1120 9.5 10.36 10.5 10.93 11.11 10.95 10.12 10.99666667 1398 1407 1381 1183 1395.333333 0.006690124 0.227892179 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane GO:0019901///protein kinase binding+++GO:0030292///protein tyrosine kinase inhibitor activity GO:0001933///negative regulation of protein phosphorylation+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0061099///negative regulation of protein tyrosine kinase activity 108841 108841 'Rdh13' mRNA 749 707 839 13.66 12.42 16.25 11.08 11.29 11.27 14.11 11.21333333 697 695 690 765 694 0.237322938 -0.15651268 00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity GO:0009644///response to high light intensity+++GO:0010842///retina layer formation+++GO:0042462///eye photoreceptor cell development+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process 108853 108853 'Mtrf1l' mRNA 220 232 120 4.66 4.84 2.7 2.25 3.71 3.4 4.066666667 3.12 122 197 179 190.6666667 166 0.538300292 -0.194613759 GO:0005739///mitochondrion GO:0003747///translation release factor activity GO:0006412///translation+++GO:0006415///translational termination+++GO:0070126///mitochondrial translational termination 108857 108857 'Ankhd1' mRNA 1037 1063 1051 6.62 6.67 7.12 6.24 6.03 6.5 6.803333333 6.256666667 1125 1062 1135 1050.333333 1107.333333 0.565673726 0.06356999 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0045087///innate immune response 108888 108888 'Atad3a' mRNA 767 756 688 17.73 17.2 16.87 16.65 17.84 17.98 17.26666667 17.49 829 867 866 737 854 0.049757769 0.20280031 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0001558///regulation of cell growth+++GO:0007005///mitochondrion organization+++GO:0043066///negative regulation of apoptotic process 108897 108897 'Aif1l' mRNA 15139 15737 15228 281.92 288.41 300.81 193.01 182.49 182.21 290.38 185.9033333 11925 11012 10901 15368 11279.33333 7.75E-18 -0.459294531 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0051017///actin filament bundle assembly+++GO:0097178///ruffle assembly 108899 108899 '2700081O15Rik' mRNA 219 223 186 2.92 2.89 2.62 2.5 2.72 2.95 2.81 2.723333333 211 225 241 209.3333333 225.6666667 0.654874915 0.100342239 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0045892///negative regulation of transcription, DNA-templated" 108900 108900 'Fam72a' mRNA 120 95.15 85 3.58 2.92 2.91 2.67 2.25 2.74 3.136666667 2.553333333 103.1 78 97 100.05 92.7 0.737431661 -0.120067161 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0031552///negative regulation of brain-derived neurotrophic factor-activated receptor activity+++GO:0043065///positive regulation of apoptotic process 108902 108902 'B4gat1' mRNA 1590 1508 1542 44.4 41.48 45.68 30.82 34.16 32.12 43.85333333 32.36666667 1269 1373 1280 1546.666667 1307.333333 0.004082697 -0.254412924 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0046872///metal ion binding+++GO:0047224///acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0007411///axon guidance+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0035269///protein O-linked mannosylation 108903 108903 'Tbcd' mRNA 1117.9 1121.58 1068 17.99 18.67 19.9 18.75 17.72 17.54 18.85333333 18.00333333 1288.37 1173.49 1150.71 1102.493333 1204.19 0.230253272 0.115083857 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction GO:0005096///GTPase activator activity+++GO:0048487///beta-tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007023///post-chaperonin tubulin folding pathway+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0031115///negative regulation of microtubule polymerization+++GO:0034333///adherens junction assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050790///regulation of catalytic activity+++GO:0070830///bicellular tight junction assembly 108907 108907 'Nusap1' mRNA 123 130 127 2.39 2.38 2.61 5.58 4.81 4.8 2.46 5.063333333 322 274.39 278.13 126.6666667 291.5066667 1.04E-11 1.188222649 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0072686///mitotic spindle GO:0003677///DNA binding+++GO:0008017///microtubule binding GO:0000070///mitotic sister chromatid segregation+++GO:0000226///microtubule cytoskeleton organization+++GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0040001///establishment of mitotic spindle localization+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0051301///cell division 108909 108909 'Aida' mRNA 654.37 619.65 309.56 10.85 10.11 5.44 6.93 10.9 9.18 8.8 9.003333333 481.17 738.88 616.85 527.86 612.3 0.643007655 0.222091656 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding GO:0007275///multicellular organism development+++GO:0009953///dorsal/ventral pattern formation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031333///negative regulation of protein complex assembly+++GO:0043254///regulation of protein complex assembly+++GO:0043508///negative regulation of JUN kinase activity+++GO:0046329///negative regulation of JNK cascade+++GO:0048264///determination of ventral identity+++GO:2000016///negative regulation of determination of dorsal identity 108911 108911 'Rcc2' mRNA 1083 1028 872 15.7 14.65 13.39 14.72 13.88 13.96 14.58 14.18666667 1166 1080 1072 994.3333333 1106 0.154558796 0.144407093 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031901///early endosome membrane+++GO:0034506///chromosome, centromeric core domain+++GO:1990023///mitotic spindle midzone" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding GO:0007049///cell cycle+++GO:0007229///integrin-mediated signaling pathway+++GO:0010762///regulation of fibroblast migration+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0030334///regulation of cell migration+++GO:0034260///negative regulation of GTPase activity+++GO:0045184///establishment of protein localization+++GO:0048041///focal adhesion assembly+++GO:0051301///cell division+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0051987///positive regulation of attachment of spindle microtubules to kinetochore+++GO:0072356///chromosome passenger complex localization to kinetochore+++GO:0090630///activation of GTPase activity+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1900027///regulation of ruffle assembly 108912 108912 'Cdca2' mRNA 6 33 22 0.09 0.41 0.34 2.16 2.39 2.66 0.28 2.403333333 170 189 206 20.33333333 188.3333333 2.47E-20 3.201831452 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007088///regulation of mitotic nuclear division+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0051301///cell division+++GO:0051983///regulation of chromosome segregation 108927 108927 'Lhfp' mRNA 769 863 731 20.86 23.06 21.04 34.8 33.74 31.03 21.65333333 33.19 1475 1396 1273 787.6666667 1381.333333 1.05E-18 0.800045854 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 108934 108934 'Smim13' mRNA 242 245 192 2.9 2.89 2.44 2.31 2.66 2.6 2.743333333 2.523333333 222 250 242 226.3333333 238 0.777269687 0.066039211 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 108937 108937 'Rnf169' mRNA 913.05 944.77 751.77 4.15 4.08 3.76 4.18 3.54 4.05 3.996666667 3.923333333 1144.43 880.38 1042.59 869.8633333 1022.466667 0.052741629 0.223632553 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0035861///site of double-strand break GO:0016740///transferase activity+++GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:2000780///negative regulation of double-strand break repair 108943 108943 'Trmt10a' mRNA 139.31 165 159 2.48 2.89 2.9 3.09 3.31 2.59 2.756666667 2.996666667 192 211.64 153.76 154.4366667 185.8 0.291338827 0.251661534 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0000049///tRNA binding+++GO:0008168///methyltransferase activity+++GO:0009019///tRNA (guanine-N1-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0052905///tRNA (guanine(9)-N(1))-methyltransferase activity GO:0002939///tRNA N1-guanine methylation+++GO:0010960///magnesium ion homeostasis+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0090646///mitochondrial tRNA processing 108946 108946 'Zzz3' mRNA 1194 1243 994 12.43 12.33 10.53 9.41 9.65 11.43 11.76333333 10.16333333 953 925 1073 1143.666667 983.6666667 0.030300048 -0.225071744 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0043967///histone H4 acetylation 108954 108954 'Ppp1r15b' mRNA 1385 1434 1458 13.18 13.42 14.72 15.47 13.96 14.32 13.77333333 14.58333333 1871 1650 1678 1425.666667 1733 0.001783881 0.267324429 GO:0000164///protein phosphatase type 1 complex+++GO:0005783///endoplasmic reticulum GO:0019888///protein phosphatase regulator activity GO:0001933///negative regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0006979///response to oxidative stress+++GO:0006983///ER overload response+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042542///response to hydrogen peroxide+++GO:0070262///peptidyl-serine dephosphorylation+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 108956 108956 'Apol7c' mRNA 3 0 1 0.08 0 0.03 0.02 0.05 0.02 0.036666667 0.03 1 2 1 1.333333333 1.333333333 0.998591786 -0.005749327 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 108958 108958 'Miga2' mRNA 1197 1099 1106 19.21 17.39 18.83 12.12 12.48 11.9 18.47666667 12.16666667 870 878 826 1134 858 7.33E-06 -0.414220166 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0008053///mitochondrial fusion+++GO:0060348///bone development 108960 108960 'Irak2' mRNA 832.55 928.24 812.12 14.28 15.67 14.82 10.69 10.17 11.24 14.92333333 10.7 715.36 667.68 731.92 857.6366667 704.9866667 0.003951686 -0.294290822 04722///Neurotrophin signaling pathway+++05152///Tuberculosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0035556///intracellular signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0046777///protein autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1 108961 108961 'E2f8' mRNA 10 1 5 0.16 0.02 0.09 1.91 2.14 2.07 0.09 2.04 147 161 154 5.333333333 154 1.32E-26 4.840948391 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001890///placenta development+++GO:0002040///sprouting angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0032466///negative regulation of cytokinesis+++GO:0032877///positive regulation of DNA endoreduplication+++GO:0033301///cell cycle comprising mitosis without cytokinesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060707///trophoblast giant cell differentiation+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0070365///hepatocyte differentiation" 108978 108978 '4930555G01Rik' mRNA 16.84 9.77 17 0.46 0.26 0.5 0.27 0.17 0.27 0.406666667 0.236666667 11.13 7.04 11 14.53666667 9.723333333 0.528753876 -0.5573796 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 108989 108989 'Tpr' mRNA 2217.39 2150.14 1863.6 15.47 14.73 13.79 14.12 16.05 15.6 14.66333333 15.25666667 2329.68 2589.07 2494.79 2077.043333 2471.18 0.002702866 0.242788664 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis+++05200///Pathways in cancer+++05216///Thyroid cancer "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery+++GO:0042405///nuclear inclusion body+++GO:0044615///nuclear pore nuclear basket+++GO:0072686///mitotic spindle" GO:0003682///chromatin binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0017056///structural constituent of nuclear pore+++GO:0031072///heat shock protein binding+++GO:0042803///protein homodimerization activity+++GO:0043495///protein membrane anchor+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070840///dynein complex binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006404///RNA import into nucleus+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006999///nuclear pore organization+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010965///regulation of mitotic sister chromatid separation+++GO:0015031///protein transport+++GO:0031453///positive regulation of heterochromatin assembly+++GO:0031647///regulation of protein stability+++GO:0031990///mRNA export from nucleus in response to heat stress+++GO:0032880///regulation of protein localization+++GO:0034605///cellular response to heat+++GO:0035457///cellular response to interferon-alpha+++GO:0042306///regulation of protein import into nucleus+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043578///nuclear matrix organization+++GO:0045947///negative regulation of translational initiation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0051301///cell division+++GO:0070849///response to epidermal growth factor+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0090316///positive regulation of intracellular protein transport+++GO:1901673///regulation of mitotic spindle assembly 108995 108995 'Tbc1d10c' mRNA 15 22 11 0.47 0.72 0.39 1.94 1.46 1.11 0.526666667 1.503333333 67 49 37 16 51 4.59E-04 1.665517607 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031527///filopodium membrane GO:0005096///GTPase activator activity "GO:0006886///intracellular protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050869///negative regulation of B cell activation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0090630///activation of GTPase activity" 109006 109006 'Ciapin1' mRNA 2621 2633 2189 79.8 79.18 70.16 55.9 59.43 57.63 76.38 57.65333333 2124 2211 2135 2481 2156.666667 0.005852731 -0.209986011 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space "GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0009055///electron transfer activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006915///apoptotic process+++GO:0016226///iron-sulfur cluster assembly+++GO:0022900///electron transport chain+++GO:0030097///hemopoiesis+++GO:0043066///negative regulation of apoptotic process 109019 109019 'Nabp1' mRNA 621 577 521 13.04 11.62 11.45 36.45 33.77 32.79 12.03666667 34.33666667 1959 1754 1695 573 1802.666667 3.37E-77 1.64267179 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0035861///site of double-strand break+++GO:0070876///SOSS complex" GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007093///mitotic cell cycle checkpoint+++GO:0010212///response to ionizing radiation+++GO:0044818///mitotic G2/M transition checkpoint 109032 109032 'Sp110' mRNA 159.64 169.76 162.25 4.77 4.95 5.23 28.79 27.06 26.8 4.983333333 27.55 1107.98 1018.95 1006.6 163.8833333 1044.51 6.52E-115 2.663598039 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0009617///response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response 109042 109042 'Cavin3' mRNA 1277 1281 1148 79.08 78.44 75.43 115.79 112.64 113.33 77.65 113.92 2144 2033 2028 1235.333333 2068.333333 3.81E-25 0.733060786 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0005080///protein kinase C binding+++GO:0005515///protein binding GO:0030866///cortical actin cytoskeleton organization+++GO:0032922///circadian regulation of gene expression+++GO:0048511///rhythmic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901003///negative regulation of fermentation 109050 109050 'Inka2' mRNA 1239 1167 1115 14.39 13.32 13.66 8.83 8.53 8.61 13.79 8.656666667 881 829 830 1173.666667 846.6666667 3.12E-08 -0.482576197 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity GO:0043086///negative regulation of catalytic activity 109052 109052 'Krt75' mRNA 0 0 1 0 0 0.02 0.04 0.1 0 0.006666667 0.046666667 3 7 0 0.333333333 3.333333333 0.20048576 3.213696991 GO:0005622///intracellular+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0002244///hematopoietic progenitor cell differentiation 109054 109054 'Pfdn4' mRNA 108 88 113 8.04 6.48 8.92 16.43 17.14 13.65 7.813333333 15.74 253 257 203 103 237.6666667 1.31E-08 1.190685938 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016272///prefoldin complex GO:0001540///amyloid-beta binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:1905907///negative regulation of amyloid fibril formation 109065 109065 'Dnaaf2' mRNA 879 1014 832 14.15 16.05 14.2 6.79 7.17 6.93 14.8 6.963333333 485 500 480 908.3333333 488.3333333 4.39E-18 -0.904255125 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0036064///ciliary basal body GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0003351///epithelial cilium movement+++GO:0010033///response to organic substance+++GO:0032526///response to retinoic acid+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0060285///cilium-dependent cell motility+++GO:0061966///establishment of left/right asymmetry+++GO:0070286///axonemal dynein complex assembly 109075 109075 'Exosc4' mRNA 1084.7 1137 1098 34.97 36.13 37.56 33.66 35.97 35.45 36.22 35.02666667 1199.95 1251.55 1222.93 1106.566667 1224.81 0.161853864 0.134234584 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035327///transcriptionally active chromatin+++GO:0043231///intracellular membrane-bounded organelle GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding "GO:0000460///maturation of 5.8S rRNA+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006364///rRNA processing+++GO:0016075///rRNA catabolic process+++GO:0030307///positive regulation of cell growth+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0045006///DNA deamination+++GO:0051607///defense response to virus+++GO:0071028///nuclear mRNA surveillance+++GO:0071044///histone mRNA catabolic process+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing" 109077 109077 'Ints5' mRNA 802 865 794 13.29 14.1 13.96 14.6 13.8 13.87 13.78333333 14.09 1014 936 933 820.3333333 961 0.026237769 0.216544308 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing 109079 109079 'Sephs1' mRNA 740 765 689 7.65 7.82 7.54 7.44 8.22 7.89 7.67 7.85 834 892 851 731.3333333 859 0.031386646 0.222345286 00450///Selenocompound metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane "GO:0000166///nucleotide binding+++GO:0004756///selenide, water dikinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0016260///selenocysteine biosynthetic process+++GO:0016310///phosphorylation 109082 109082 'Fbxw17' mRNA 398 401 434 10.88 10.98 13.78 14.49 17.93 14.29 11.88 15.57 586 663 545 411 598 8.01E-05 0.527773757 GO:0005575///cellular_component GO:0003674///molecular_function 109093 109093 'Rars2' mRNA 473 497 477 13.69 14.17 14.39 12.94 14.23 10.7 14.08333333 12.62333333 521 549 414 482.3333333 494.6666667 0.888356807 0.024560336 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004814///arginine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006420///arginyl-tRNA aminoacylation+++GO:0032543///mitochondrial translation 109095 109095 'Rbm15b' mRNA 250 234 237 2.16 1.98 2.17 2.4 2.29 2.36 2.103333333 2.35 320 299 305 240.3333333 308 0.030755832 0.345408971 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001510///RNA methylation+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0045892///negative regulation of transcription, DNA-templated" 109108 109108 'Slc30a9' mRNA 2456 2468 1440 39.24 38.8 24.4 17.87 28.72 26.79 34.14666667 24.46 1287 2021 1868 2121.333333 1725.333333 0.409175824 -0.29301912 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003682///chromatin binding+++GO:0008324///cation transmembrane transporter activity+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 109113 109113 'Uhrf2' mRNA 282 266 238 4.35 4.03 3.9 4.65 5.08 5.29 4.093333333 5.006666667 346 371 384 262 367 0.001385522 0.47733669 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061630///ubiquitin protein ligase activity GO:0007049///cell cycle+++GO:0010216///maintenance of DNA methylation+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0051865///protein autoubiquitination+++GO:0071158///positive regulation of cell cycle arrest 109115 109115 'Supt3' mRNA 194 222 159 7.67 8.66 6.84 5.37 5.39 5.48 7.723333333 5.413333333 156 153 152 191.6666667 153.6666667 0.125064489 -0.32541493 05202///Transcriptional misregulation in cancer GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity "GO:0006366///transcription by RNA polymerase II+++GO:0016578///histone deubiquitination+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated" 109129 109129 'Mmadhc' mRNA 1563 1526 1473 63.99 61.41 63.91 68.66 73.42 74.64 63.10333333 72.24 1919 1999 2005 1520.666667 1974.333333 1.19E-06 0.365713352 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0009235///cobalamin metabolic process 109135 109135 'Plekha5' mRNA 1105 1160 1066 12.07 12.45 12.31 7.55 5.87 6.12 12.27666667 6.513333333 792 604 625 1110.333333 673.6666667 3.58E-12 -0.734319214 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse "GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0061458///reproductive system development 109136 109136 'Mmaa' mRNA 667 729 640 4.84 5.27 4.72 3.48 3.57 3.39 4.943333333 3.48 539.65 516.02 541 678.6666667 532.2233333 9.16E-04 -0.361764519 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016530///metallochaperone activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0008150///biological_process+++GO:0009235///cobalamin metabolic process 109145 109145 'Gins4' mRNA 862 815 821 37.92 35.38 38.31 37.5 41.23 38.3 37.20333333 39.01 979 1050 967 832.6666667 998.6666667 0.0128847 0.25076095 GO:0000811///GINS complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0071162///CMG complex GO:0005515///protein binding GO:0000727///double-strand break repair via break-induced replication+++GO:0001833///inner cell mass cell proliferation+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication 109151 109151 'Chd9' mRNA 2532.86 2713.02 2496.43 8.91 9.2 9.5 6.55 5.78 5.92 9.203333333 6.083333333 2247.38 1950.95 1978.98 2580.77 2059.103333 3.16E-06 -0.338553204 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0006325///chromatin organization+++GO:0008150///biological_process+++GO:0032508///DNA duplex unwinding 109154 109154 'Mlec' mRNA 3664 3971 1851 32.64 34.75 17.5 22.04 26.75 26.93 28.29666667 25.24 2847 3379 3371 3162 3199 0.960250673 0.023375396 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding GO:0005975///carbohydrate metabolic process 109161 109161 'Ube2q2' mRNA 560 523 519 10.83 9.95 10.61 8.28 8.37 7.7 10.46333333 8.116666667 499 499 451 534 483 0.244028028 -0.156600994 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination 109168 109168 'Atl3' mRNA 386 364 313 4.15 3.91 3.7 6.71 5.6 6.82 3.92 6.376666667 728 572 679 354.3333333 659.6666667 2.02E-12 0.88590902 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098826///endoplasmic reticulum tubular network membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0051260///protein homooligomerization+++GO:1903373///positive regulation of endoplasmic reticulum tubular network organization 109169 109169 'Igip' mRNA 132.55 161.93 119.48 5.76 6.94 5.51 6.31 5 6.43 6.07 5.913333333 166.68 128.89 164.31 137.9866667 153.2933333 0.603210624 0.143445521 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 109181 109181 'Trip11' mRNA 1830.04 1732 1654 11.24 10.54 10.83 10.56 9.71 10.01 10.87 10.09333333 1953 1719.1 1800 1738.68 1824.033333 0.544165874 0.057085424 GO:0002079///inner acrosomal membrane+++GO:0002080///acrosomal membrane+++GO:0002081///outer acrosomal membrane+++GO:0005654///nucleoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0003281///ventricular septum development+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0006486///protein glycosylation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0051216///cartilage development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060348///bone development+++GO:0090161///Golgi ribbon formation+++GO:0099041///vesicle tethering to Golgi+++GO:1903441///protein localization to ciliary membrane 109205 109205 'Sobp' mRNA 456.32 452.86 390.73 3.13 3.09 2.68 1.28 1.37 1.41 2.966666667 1.353333333 209.81 246.35 232.04 433.3033333 229.4 1.34E-10 -0.925812595 GO:0005634///nucleus GO:0032184///SUMO polymer binding+++GO:0046872///metal ion binding GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0042472///inner ear morphogenesis+++GO:0050890///cognition+++GO:0090102///cochlea development 109212 109212 'Pimreg' mRNA 0 7 7 0 0.28 0.41 9.34 9.27 8.43 0.23 9.013333333 257 249 227 4.666666667 244.3333333 1.12E-37 5.69737215 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0051301///cell division 109218 109218 'Tmem139' mRNA 107 134 95 5.16 6.45 4.95 3.19 3.65 3.6 5.52 3.48 78 82 81 112 80.33333333 0.076837309 -0.485822087 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 109222 109222 'Rarres1' mRNA 89 132 108 3.76 5.51 4.84 2.47 3.89 2.44 4.703333333 2.933333333 67 103 64 109.6666667 78 0.116160004 -0.49914912 GO:0005615///extracellular space GO:0008191///metalloendopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity 109225 109225 'Ms4a7' mRNA 167 177 215 7.56 7.88 10.33 122.43 130.03 118.72 8.59 123.7266667 3098 3214 2907 186.3333333 3073 0 4.02938569 GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 109229 109229 'Fam118b' mRNA 610 565 557 22.19 20.04 22.36 31.81 32.83 30.19 21.53 31.61 1011 993 928 577.3333333 977.3333333 2.21E-14 0.747823468 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0015030///Cajal body GO:0042802///identical protein binding GO:0008150///biological_process+++GO:0030576///Cajal body organization 109232 109232 'Sccpdh' mRNA 3318 3447 3421 98.09 100.49 107.32 53.49 56.61 56.84 101.9666667 55.64666667 2077 2146 2138 3395.333333 2120.333333 1.22E-23 -0.691641506 GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity GO:0009247///glycolipid biosynthetic process 109241 109241 'Mbd5' mRNA 994 1050 827 6.37 6.51 5.64 2.63 2.54 3.02 6.173333333 2.73 481 444 528 957 484.3333333 9.42E-20 -0.990341586 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0010369///chromocenter+++GO:0030496///midbody GO:0003677///DNA binding+++GO:0003682///chromatin binding GO:0007399///nervous system development+++GO:0040014///regulation of multicellular organism growth+++GO:0042593///glucose homeostasis+++GO:0050795///regulation of behavior+++GO:0060399///positive regulation of growth hormone receptor signaling pathway 109242 109242 'Kif24' mRNA 498.41 536.56 485.95 2.87 3.29 2.82 1.15 1.02 1.21 2.993333333 1.126666667 238.54 206.49 224.3 506.9733333 223.11 2.08E-19 -1.196946842 04361///Axon regeneration GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0007019///microtubule depolymerization+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly 109245 109245 'Lrrc39' mRNA 26.03 31.36 20.93 0.57 0.73 0.53 0.5 0.43 0.44 0.61 0.456666667 27.36 22.93 20.15 26.10666667 23.48 0.811289805 -0.165190784 GO:0005737///cytoplasm+++GO:0031430///M band+++GO:0043231///intracellular membrane-bounded organelle GO:0004722///protein serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction 109246 109246 'Tspan9' mRNA 441 483 396 6.09 6.57 5.78 9.31 7.97 7.77 6.146666667 8.35 784 656 635 440 691.6666667 7.93E-08 0.641913928 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097197///tetraspanin-enriched microdomain GO:0003674///molecular_function 109254 109254 'Adtrp' mRNA 3 0 0 0.09 0 0 0.02 0 0.09 0.03 0.036666667 1 0 1 1 0.666666667 0.876679435 -0.58285425 GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002686///negative regulation of leukocyte migration+++GO:0003332///negative regulation of extracellular matrix constituent secretion+++GO:0006629///lipid metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0030195///negative regulation of blood coagulation+++GO:0042758///long-chain fatty acid catabolic process+++GO:0043491///protein kinase B signaling+++GO:0050709///negative regulation of protein secretion+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:2000402///negative regulation of lymphocyte migration 109263 109263 'Rlf' mRNA 897 899 498 7.01 6.95 4.2 3.8 3.59 3.67 6.053333333 3.686666667 555 519 526 764.6666667 533.3333333 0.001665705 -0.519783582 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0044030///regulation of DNA methylation+++GO:0097692///histone H3-K4 monomethylation 109264 109264 'Me3' mRNA 1521.41 1610.68 1546.85 22.45 23.52 24.16 14.44 14.11 14.74 23.37666667 14.43 1141.64 1116.53 1154.53 1559.646667 1137.566667 5.45E-09 -0.467476946 00620///Pyruvate metabolism+++01200///Carbon metabolism+++03320///PPAR signaling pathway GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004470///malic enzyme activity+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051287///NAD binding+++GO:0070401///NADP+ binding GO:0006090///pyruvate metabolic process+++GO:0006108///malate metabolic process 109267 109267 'Ssc4d' mRNA 1062 1101 1064 20.86 21.38 22.22 10.96 9.93 10.82 21.48666667 10.57 640 565 613 1075.666667 606 4.65E-19 -0.840694288 GO:0005576///extracellular region+++GO:0016020///membrane GO:0005044///scavenger receptor activity GO:0006897///endocytosis+++GO:0008150///biological_process 109270 109270 'Prr5' mRNA 367.23 482.05 207.02 9.37 11.95 4.71 2.48 3.97 3.29 8.676666667 3.246666667 131 180 159.68 352.1 156.8933333 1.23E-06 -1.161033433 04150///mTOR signaling pathway GO:0031932///TORC2 complex GO:0005096///GTPase activator activity GO:0001934///positive regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0038203///TORC2 signaling+++GO:0050790///regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 109272 109272 'Mybpc1' mRNA 6192 6082 6103 85.19 82.27 89.05 30.19 27.15 28.53 85.50333333 28.62333333 2532 2221 2314 6125.666667 2355.666667 1.09E-107 -1.392476015 GO:0005856///cytoskeleton GO:0005200///structural constituent of cytoskeleton+++GO:0017022///myosin binding GO:0006936///muscle contraction+++GO:0007010///cytoskeleton organization 109275 109275 'Actr5' mRNA 59 97 47 2.11 3.04 1.86 2.05 1.67 1.82 2.336666667 1.846666667 63 53 55 67.66666667 57 0.560541708 -0.24965221 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031011///Ino80 complex "GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0070914///UV-damage excision repair" 109284 109284 'R3hdm4' mRNA 2591 2630 2473 81.8 81.83 82.84 79.07 72.79 79.99 82.15666667 77.28333333 2879 2586 2819 2564.666667 2761.333333 0.202197708 0.094601577 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0008150///biological_process 109294 109294 'Prex2' mRNA 453 510 472 2.93 3.38 3.15 2.3 2.4 2.25 3.153333333 2.316666667 430 417.03 389 478.3333333 412.01 0.094253706 -0.2273154 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008344///adult locomotory behavior+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0035556///intracellular signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0050790///regulation of catalytic activity 109299 109299 'Tmem250-ps' mRNA 4945 4819 4658 119.45 114.71 119.69 119.92 113.49 112.99 117.95 115.4666667 5695 5266 5196 4807.333333 5385.666667 0.012555867 0.151582319 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008284///positive regulation of cell proliferation+++GO:0048524///positive regulation of viral process 109305 109305 'Orai1' mRNA 200 215 121 6.42 7 4.5 6.59 7.23 8.44 5.973333333 7.42 218 234 269 178.6666667 240.3333333 0.056193283 0.427352274 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04611///Platelet activation+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++05340///Primary immunodeficiency GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015279///store-operated calcium channel activity+++GO:0042802///identical protein binding GO:0002115///store-operated calcium entry+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0051924///regulation of calcium ion transport+++GO:0051928///positive regulation of calcium ion transport+++GO:0061180///mammary gland epithelium development+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport 109323 109323 'C1qtnf7' mRNA 32 29 29 1.24 1.04 1.01 1.62 1.76 1.63 1.096666667 1.67 54 53 51 30 52.66666667 0.045044968 0.800346901 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007283///spermatogenesis+++GO:0045444///fat cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation 109331 109331 'Rnf20' mRNA 1090 1162 989 13.57 14.2 13.01 13.78 12.05 12.78 13.59333333 12.87 1279 1075 1152 1080.333333 1168.666667 0.326723953 0.102549157 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0033503///HULC complex GO:0002039///p53 binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000209///protein polyubiquitination+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010390///histone monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0030336///negative regulation of cell migration+++GO:0031062///positive regulation of histone methylation+++GO:0033523///histone H2B ubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:2001168///positive regulation of histone H2B ubiquitination" 109332 109332 'Cdcp1' mRNA 237 293 211 2.55 2.95 2.43 2.86 2.87 3.09 2.643333333 2.94 307 291 336 247 311.3333333 0.060196205 0.326748464 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008150///biological_process 109333 109333 'Pkn2' mRNA 652 550 411 5.57 4.62 3.72 3.98 3.39 3.98 4.636666667 3.783333333 537 447 520 537.6666667 501.3333333 0.561348178 -0.107063021 04151///PI3K-Akt signaling pathway+++04621///NOD-like receptor signaling pathway+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043296///apical junction complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0042826///histone deacetylase binding+++GO:0070063///RNA polymerase binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0010631///epithelial cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030030///cell projection organization+++GO:0032467///positive regulation of cytokinesis+++GO:0035556///intracellular signal transduction+++GO:0043297///apical junction assembly+++GO:0045070///positive regulation of viral genome replication+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:2000145///regulation of cell motility 109342 109342 'Slc5a10' mRNA 2.03 0 1.03 0.06 0 0.05 0 0 0 0.036666667 0 0 0 0 1.02 0 0.60428608 -2.461629596 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005412///glucose:sodium symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport 109346 109346 'Ankrd39' mRNA 559 619 575 17.44 19.03 19.01 15.64 12.15 12.28 18.49333333 13.35666667 576 437 438 584.3333333 483.6666667 0.038170751 -0.287011961 GO:0030315///T-tubule GO:0003674///molecular_function GO:0036371///protein localization to T-tubule+++GO:0055117///regulation of cardiac muscle contraction 109349 109349 'Fam163b' mRNA 52 48 46 0.97 0.88 0.91 0 0 0.07 0.92 0.023333333 0 0 4 48.66666667 1.333333333 3.90E-09 -5.199679764 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 109359 109359 'Abraxas2' mRNA 468 558 530 8.9 10.45 10.69 12.52 11.88 12.94 10.01333333 12.44666667 757 702 758 518.6666667 739 1.58E-05 0.497752565 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0031616///spindle pole centrosome+++GO:0036449///microtubule minus-end+++GO:0070552///BRISC complex GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031593///polyubiquitin modification-dependent protein binding GO:0000278///mitotic cell cycle+++GO:0002931///response to ischemia+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0043066///negative regulation of apoptotic process+++GO:0051301///cell division+++GO:0070536///protein K63-linked deubiquitination+++GO:0071497///cellular response to freezing+++GO:0090307///mitotic spindle assembly 109552 109552 'Sri' mRNA 3226 3413 3335 75.09 78.21 82.33 68.06 71.48 66.22 78.54333333 68.58666667 3364 3450 3167 3324.666667 3327 0.901147071 -0.011354759 GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0031982///vesicle+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042584///chromaffin granule membrane+++GO:0043679///axon terminus+++GO:0044326///dendritic spine neck+++GO:0070062///extracellular exosome GO:0002020///protease binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0070491///repressing transcription factor binding GO:0006816///calcium ion transport+++GO:0007507///heart development+++GO:0010459///negative regulation of heart rate+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051924///regulation of calcium ion transport+++GO:0055118///negative regulation of cardiac muscle contraction+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:1901077///regulation of relaxation of muscle+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:2000678///negative regulation of transcription regulatory region DNA binding 109593 109593 'Lmo3' mRNA 22 23 31 0.68 0.46 0.96 0.05 0.14 0.03 0.7 0.073333333 4 4 2 25.33333333 3.333333333 1.22E-04 -2.946751349 GO:0005737///cytoplasm GO:0046872///metal ion binding GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway 109594 109594 'Lmo1' mRNA 655 623 495 39.48 37.15 31.31 10.05 10.94 11.14 35.98 10.71 190 200 199 591 196.3333333 7.96E-31 -1.596455889 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046013///regulation of T cell homeostatic proliferation 109620 109620 'Dsp' mRNA 757 784 695 4.34 4.47 4.34 5.08 4.31 4.42 4.383333333 4.603333333 1035 855 871 745.3333333 920.3333333 0.005195244 0.292453823 05412///Arrhythmogenic right ventricular cardiomyopathy GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005916///fascia adherens+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0005080///protein kinase C binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0097110///scaffold protein binding GO:0002934///desmosome organization+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0034332///adherens junction organization+++GO:0042060///wound healing+++GO:0043588///skin development+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045109///intermediate filament organization+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090136///epithelial cell-cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential 109624 109624 'Cald1' mRNA 2795 2921 2775 36.02 37.26 38.14 59.57 61.37 59.83 37.14 60.25666667 5279 5300 5158 2830.333333 5245.666667 5.18E-51 0.878567164 04270///Vascular smooth muscle contraction GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030478///actin cap+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0017022///myosin binding GO:0001525///angiogenesis+++GO:0006936///muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0032092///positive regulation of protein binding+++GO:0051017///actin filament bundle assembly+++GO:0071559///response to transforming growth factor beta 109637 109637 'Upk1a' mRNA 20 13 10 0.92 0.59 0.49 0.85 0.7 0.67 0.666666667 0.74 21 17 16 14.33333333 18 0.691360852 0.322018482 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032991///protein-containing complex+++GO:0120001///apical plasma membrane urothelial plaque GO:0005515///protein binding GO:0030855///epithelial cell differentiation 109648 109648 'Npy' mRNA 57 47 53 7.93 6.52 7.83 6.84 8.55 8.11 7.426666667 7.833333333 56 68 64 52.33333333 62.66666667 0.536704255 0.248489926 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04920///Adipocytokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++05034///Alcoholism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0098992///neuronal dense core vesicle GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0031841///neuropeptide Y receptor binding GO:0001878///response to yeast+++GO:0002865///negative regulation of acute inflammatory response to antigenic stimulus+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007631///feeding behavior+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0008343///adult feeding behavior+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0031175///neuron projection development+++GO:0032100///positive regulation of appetite+++GO:0032903///regulation of nerve growth factor production+++GO:0042117///monocyte activation+++GO:0045087///innate immune response+++GO:0045776///negative regulation of blood pressure+++GO:0045964///positive regulation of dopamine metabolic process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901215///negative regulation of neuron death+++GO:1904000///positive regulation of eating behavior+++GO:1904407///positive regulation of nitric oxide metabolic process 109652 109652 'Acy1' mRNA 641 653 569 26.41 26.55 24.89 21.62 19.05 17.46 25.95 19.37666667 603 518 471 621 530.6666667 0.062259519 -0.237924632 00220///Arginine biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0070062///extracellular exosome GO:0004046///aminoacylase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006520///cellular amino acid metabolic process 109658 109658 'Txlna' mRNA 1829 1866 1841 21.06 21.25 22.54 17.35 17.13 17.62 21.61666667 17.36666667 1734 1666 1702 1845.333333 1700.666667 0.106044599 -0.130380372 GO:0005737///cytoplasm GO:0019905///syntaxin binding GO:0006887///exocytosis+++GO:0042113///B cell activation 109660 109660 'Ctrl' mRNA 5 1 4 0.37 0.07 0.32 0.45 0.2 0.27 0.253333333 0.306666667 7 3 4 3.333333333 4.666666667 0.786888308 0.45735438 04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 109672 109672 'Cyb5a' mRNA 6138 6348 6104 495.51 507.7 522.9 403.38 433.91 407.05 508.7033333 414.78 5721 5994 5575 6196.666667 5763.333333 0.080756983 -0.116133533 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0009055///electron transfer activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0006631///fatty acid metabolic process+++GO:0022900///electron transport chain+++GO:0046686///response to cadmium ion 109674 109674 'Ampd2' mRNA 1329.13 1409.37 1319.1 21.28 21.93 22.2 21.95 21.07 20.87 21.80333333 21.29666667 1606.16 1510.82 1485.11 1352.533333 1534.03 0.040794699 0.169567169 00230///Purine metabolism GO:0005829///cytosol GO:0003876///AMP deaminase activity+++GO:0016787///hydrolase activity+++GO:0019239///deaminase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006188///IMP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0042632///cholesterol homeostasis+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046039///GTP metabolic process+++GO:0052652///cyclic purine nucleotide metabolic process+++GO:0072015///glomerular visceral epithelial cell development+++GO:0097009///energy homeostasis 109676 109676 'Ank2' mRNA 2086.04 2152.21 1850.14 8.51 8.85 8.32 12.78 10.58 11.9 8.56 11.75333333 3343.77 2811.4 3081.57 2029.463333 3078.913333 1.27E-16 0.590360334 04624///Toll and Imd signaling pathway+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0031430///M band+++GO:0031672///A band+++GO:0033010///paranodal junction+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043034///costamere+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome "GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030507///spectrin binding+++GO:0030674///protein binding, bridging+++GO:0044325///ion channel binding+++GO:0051117///ATPase binding+++GO:0140031///phosphorylation-dependent protein binding" GO:0002027///regulation of heart rate+++GO:0003283///atrial septum development+++GO:0006874///cellular calcium ion homeostasis+++GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008104///protein localization+++GO:0010628///positive regulation of gene expression+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0015031///protein transport+++GO:0030913///paranodal junction assembly+++GO:0031647///regulation of protein stability+++GO:0033292///T-tubule organization+++GO:0033365///protein localization to organelle+++GO:0034394///protein localization to cell surface+++GO:0034613///cellular protein localization+++GO:0036309///protein localization to M-band+++GO:0036371///protein localization to T-tubule+++GO:0042981///regulation of apoptotic process+++GO:0043268///positive regulation of potassium ion transport+++GO:0050821///protein stabilization+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051597///response to methylmercury+++GO:0051924///regulation of calcium ion transport+++GO:0051928///positive regulation of calcium ion transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060048///cardiac muscle contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0070972///protein localization to endoplasmic reticulum+++GO:0072659///protein localization to plasma membrane+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086015///SA node cell action potential+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0086066///atrial cardiac muscle cell to AV node cell communication+++GO:0086070///SA node cell to atrial cardiac muscle cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098904///regulation of AV node cell action potential+++GO:0098907///regulation of SA node cell action potential+++GO:0098910///regulation of atrial cardiac muscle cell action potential+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1901019///regulation of calcium ion transmembrane transporter activity+++GO:1901021///positive regulation of calcium ion transmembrane transporter activity+++GO:2001257///regulation of cation channel activity+++GO:2001259///positive regulation of cation channel activity 109685 109685 'Hyal3' mRNA 235.4 244.86 265.09 7.4 7.58 8.84 4.78 5.04 5.23 7.94 5.016666667 174.92 179.87 185.16 248.45 179.9833333 0.008491069 -0.481833343 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0097225///sperm midpiece "GO:0001618///virus receptor activity+++GO:0003824///catalytic activity+++GO:0004415///hyalurononglucosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0033906///hyaluronoglucuronidase activity" GO:0001552///ovarian follicle atresia+++GO:0005975///carbohydrate metabolic process+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007341///penetration of zona pellucida+++GO:0008152///metabolic process+++GO:0009615///response to virus+++GO:0030214///hyaluronan catabolic process+++GO:0046677///response to antibiotic+++GO:0046718///viral entry into host cell+++GO:0051216///cartilage development+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071493///cellular response to UV-B+++GO:2000355///negative regulation of ovarian follicle development+++GO:2000368///positive regulation of acrosomal vesicle exocytosis 109689 109689 'Arrb1' mRNA 963 984 878 7.28 7.35 7.06 6.42 6.41 6.86 7.23 6.563333333 975 951 1008 941.6666667 978 0.711506064 0.044474461 "04010///MAPK signaling pathway+++04062///Chemokine signaling pathway+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++05032///Morphine addiction+++05207///Chemical carcinogenesis - receptor activation" GO:0000785///chromatin+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016604///nuclear body+++GO:0031143///pseudopodium+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane GO:0001664///G protein-coupled receptor binding+++GO:0003713///transcription coactivator activity+++GO:0005096///GTPase activator activity+++GO:0005102///signaling receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0030276///clathrin binding+++GO:0030331///estrogen receptor binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031691///alpha-1A adrenergic receptor binding+++GO:0031692///alpha-1B adrenergic receptor binding+++GO:0031701///angiotensin receptor binding+++GO:0031762///follicle-stimulating hormone receptor binding+++GO:0031896///V2 vasopressin receptor binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0044325///ion channel binding+++GO:0045309///protein phosphorylated amino acid binding+++GO:0051219///phosphoprotein binding+++GO:1990763///arrestin family protein binding "GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002031///G protein-coupled receptor internalization+++GO:0002092///positive regulation of receptor internalization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007602///phototransduction+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009968///negative regulation of signal transduction+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032092///positive regulation of protein binding+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035066///positive regulation of histone acetylation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042493///response to drug+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043149///stress fiber assembly+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090240///positive regulation of histone H4 acetylation" 109697 109697 'Cpa1' mRNA 0 0 1 0 0 0.04 0 0.03 0 0.013333333 0.01 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008238///exopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 109700 109700 'Itga1' mRNA 150 139 114 1.33 1.21 1.07 2.15 2.26 2.11 1.203333333 2.173333333 279 287 265 134.3333333 277 5.25E-09 1.036130756 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034665///integrin alpha1-beta1 complex+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045178///basal part of cell GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0019903///protein phosphatase binding+++GO:0046872///metal ion binding+++GO:0098639///collagen binding involved in cell-matrix adhesion GO:0000187///activation of MAPK activity+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0030593///neutrophil chemotaxis+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042311///vasodilation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045123///cellular extravasation+++GO:0048812///neuron projection morphogenesis+++GO:0060326///cell chemotaxis 109711 109711 'Actn1' mRNA 989 1014 553 14.47 14.49 8.63 8.97 8.49 9.5 12.53 8.986666667 702 656 721 852 693 0.080189374 -0.297561041 04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05146///Amoebiasis+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0005916///fascia adherens+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0032127///dense core granule membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0098978///glutamatergic synapse GO:0003725///double-stranded RNA binding+++GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0017166///vinculin binding+++GO:0019904///protein domain specific binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0099186///structural constituent of postsynapse "GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0030220///platelet formation+++GO:0030865///cortical cytoskeleton organization+++GO:0036344///platelet morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048041///focal adhesion assembly+++GO:0051017///actin filament bundle assembly+++GO:0051271///negative regulation of cellular component movement+++GO:0051639///actin filament network formation+++GO:0055001///muscle cell development+++GO:0099173///postsynapse organization" 109729085 109729085 'Htd2' mRNA 23.98 31.13 0 0.54 0.69 0 0.59 0.16 0.16 0.41 0.303333333 29.99 7.9 8.12 18.37 15.33666667 0.829035313 -0.284417377 00061///Fatty acid biosynthesis+++01212///Fatty acid metabolism GO:0005730///nucleolus+++GO:0005739///mitochondrion 109731 109731 'Maob' mRNA 1111 1207 1252 25.74 27.54 30.77 52.08 52.49 53.34 28.01666667 52.63666667 2585 2544 2563 1190 2564 1.38E-41 1.09345026 "00260///Glycine, serine and threonine metabolism+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism" GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008131///primary amine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0097621///monoamine oxidase activity GO:0009636///response to toxic substance+++GO:0010044///response to aluminum ion+++GO:0010269///response to selenium ion+++GO:0014063///negative regulation of serotonin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0042135///neurotransmitter catabolic process+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0045964///positive regulation of dopamine metabolic process+++GO:0051412///response to corticosterone 109754 109754 'Cyb5r3' mRNA 9172 9532 9008 254.8 261.18 265.23 304.65 305.19 298.03 260.4033333 302.6233333 12565 12284 11902 9237.333333 12250.33333 6.34E-15 0.39546723 00520///Amino sugar and nucleotide sugar metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:1903958///nitric-oxide synthase complex "GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0005515///protein binding+++GO:0016208///AMP binding+++GO:0016491///oxidoreductase activity+++GO:0043531///ADP binding+++GO:0050421///nitrite reductase (NO-forming) activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0071949///FAD binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016126///sterol biosynthetic process 109778 109778 'Blvra' mRNA 433 468 425 22.65 24.28 23.62 53.39 55.37 51.34 23.51666667 53.36666667 1184 1201 1101 442 1162 5.94E-46 1.383706227 00860///Porphyrin metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004074///biliverdin reductase activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0042167///heme catabolic process 109785 109785 'Pgm3' mRNA 822.21 786.2 748.45 17.58 16.66 16.97 23.05 20.18 23.26 17.07 22.16333333 1164.22 1017.97 1101.58 785.62 1094.59 3.80E-07 0.46625417 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars "GO:0000287///magnesium ion binding+++GO:0004610///phosphoacetylglucosamine mutase activity+++GO:0004614///phosphoglucomutase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0007283///spermatogenesis+++GO:0009790///embryo development+++GO:0019255///glucose 1-phosphate metabolic process+++GO:0030097///hemopoiesis+++GO:0071704///organic substance metabolic process 109791 109791 'Clps' mRNA 5 8 6 0.73 1.16 0.93 0 0 0 0.94 0 0 0 0 6.333333333 0 0.005931924 -5.114899469 04975///Fat digestion and absorption GO:0005576///extracellular region GO:0008047///enzyme activator activity GO:0006629///lipid metabolic process+++GO:0007586///digestion+++GO:0009617///response to bacterium+++GO:0016042///lipid catabolic process+++GO:0032094///response to food+++GO:0043085///positive regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 109801 109801 'Glo1' mRNA 2889 3042 3029 87.95 92.29 100.06 103.17 95.44 98.75 93.43333333 99.12 3670 3327 3442 2986.666667 3479.666667 0.003603626 0.206630344 00620///Pyruvate metabolism GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0004462///lactoylglutathione lyase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding GO:0005975///carbohydrate metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006749///glutathione metabolic process+++GO:0009438///methylglyoxal metabolic process+++GO:0019243///methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione+++GO:0030316///osteoclast differentiation+++GO:0043066///negative regulation of apoptotic process 109815 109815 'Selenos' mRNA 2291 2547 2460 118.29 129.86 134.78 145.58 158.78 143.23 127.6433333 149.1966667 3235 3441 3078 2432.666667 3251.333333 1.93E-07 0.406345068 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0036502///Derlin-1-VIMP complex+++GO:0036513///Derlin-1 retrotranslocation complex GO:0005515///protein binding+++GO:0016209///antioxidant activity+++GO:0019899///enzyme binding+++GO:0051117///ATPase binding+++GO:1990381///ubiquitin-specific protease binding "GO:0002865///negative regulation of acute inflammatory response to antigenic stimulus+++GO:0006886///intracellular protein transport+++GO:0006983///ER overload response+++GO:0009749///response to glucose+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034599///cellular response to oxidative stress+++GO:0045454///cell redox homeostasis+++GO:0050728///negative regulation of inflammatory response+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0051775///response to redox state+++GO:0071222///cellular response to lipopolysaccharide+++GO:0080164///regulation of nitric oxide metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:2000110///negative regulation of macrophage apoptotic process" 109820 109820 'Pgc' mRNA 9 3 4 0.39 0.13 0.18 0.6 0.08 0.27 0.233333333 0.316666667 16 2 7 5.333333333 8.333333333 0.641597089 0.62165976 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0002803///positive regulation of antibacterial peptide production+++GO:0006508///proteolysis+++GO:0007586///digestion 109821 109821 'F11' mRNA 3 7 6 0.07 0.15 0.14 0 0 0 0.12 0 0 0 0 5.333333333 0 0.013739581 -4.872420263 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0070009///serine-type aminopeptidase activity GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030193///regulation of blood coagulation+++GO:0031639///plasminogen activation+++GO:0051919///positive regulation of fibrinolysis 109828 109828 'C7' mRNA 29 37 19 0.51 0.64 0.35 0.06 0.12 0.14 0.5 0.106666667 4 8 9 28.33333333 7 0.002189839 -2.01358122 04610///Complement and coagulation cascades+++05020///Prion disease+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005579///membrane attack complex "GO:0006883///cellular sodium ion homeostasis+++GO:0006958///complement activation, classical pathway+++GO:0019835///cytolysis+++GO:0045087///innate immune response" 109857 109857 'Cbr3' mRNA 96 106 95 5.08 5.54 5.33 13.65 11.07 13.26 5.316666667 12.66 296 234 278 99 269.3333333 4.20E-14 1.431418759 00590///Arachidonic acid metabolism+++00980///Metabolism of xenobiotics by cytochrome P450 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000253///3-keto sterol reductase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0070402///NADPH binding GO:0042376///phylloquinone catabolic process+++GO:0050890///cognition 109880 109880 'Braf' mRNA 1081 1211 1253 5.83 6.52 7.23 4.27 4 4.03 6.526666667 4.1 904 832 824 1181.666667 853.3333333 2.04E-06 -0.484743435 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04150///mTOR signaling pathway+++04214///Apoptosis - fly+++04270///Vascular smooth muscle contraction+++04320///Dorso-ventral axis formation+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding "GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0002318///myeloid progenitor cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008152///metabolic process+++GO:0008542///visual learning+++GO:0010628///positive regulation of gene expression+++GO:0010764///negative regulation of fibroblast migration+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0030878///thyroid gland development+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035019///somatic stem cell population maintenance+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043367///CD4-positive, alpha-beta T cell differentiation+++GO:0043368///positive T cell selection+++GO:0043369///CD4-positive or CD8-positive, alpha-beta T cell lineage commitment+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045580///regulation of T cell differentiation+++GO:0046632///alpha-beta T cell differentiation+++GO:0048538///thymus development+++GO:0048679///regulation of axon regeneration+++GO:0048680///positive regulation of axon regeneration+++GO:0050772///positive regulation of axonogenesis+++GO:0050852///T cell receptor signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051591///response to cAMP+++GO:0060291///long-term synaptic potentiation+++GO:0060323///head morphogenesis+++GO:0060324///face development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070413///trehalose metabolism in response to stress+++GO:0071277///cellular response to calcium ion+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0090150///establishment of protein localization to membrane+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000301///negative regulation of synaptic vesicle exocytosis+++GO:2000352///negative regulation of endothelial cell apoptotic process" 109889 109889 'Mzf1' mRNA 137.89 134.96 98.06 2.12 1.68 1.64 0.71 0.87 0.88 1.813333333 0.82 58.26 68.09 65.42 123.6366667 63.92333333 3.65E-04 -0.954653178 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 109900 109900 'Asl' mRNA 613 665 662 21.66 23.03 24.53 32.35 34.02 32.31 23.07333333 32.89333333 1048 1087 1020 646.6666667 1051.666667 3.26E-12 0.689053462 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01230///Biosynthesis of amino acids" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0070852///cell body fiber GO:0003824///catalytic activity+++GO:0004056///argininosuccinate lyase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding GO:0000050///urea cycle+++GO:0000053///argininosuccinate metabolic process+++GO:0001889///liver development+++GO:0006520///cellular amino acid metabolic process+++GO:0006526///arginine biosynthetic process+++GO:0007626///locomotory behavior+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009791///post-embryonic development+++GO:0019676///ammonia assimilation cycle+++GO:0042450///arginine biosynthetic process via ornithine 109901 109901 'Cela1' mRNA 12 7 19 0.68 0.39 1.14 17.58 19.14 17.47 0.736666667 18.06333333 357 379 343 12.66666667 359.6666667 8.76E-60 4.812573085 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:0009791///post-embryonic development+++GO:0016055///Wnt signaling pathway+++GO:0031017///exocrine pancreas development+++GO:0035264///multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0045595///regulation of cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048771///tissue remodeling+++GO:0055123///digestive system development+++GO:0060309///elastin catabolic process+++GO:0061113///pancreas morphogenesis 109904 109904 'Mcf2' mRNA 0 1 1 0 0.01 0.02 0 0 0.05 0.01 0.016666667 0 0 4 0.666666667 1.333333333 0.79493747 0.983601392 GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0016358///dendrite development+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity+++GO:1990830///cellular response to leukemia inhibitory factor 109905 109905 'Rap1a' mRNA 1040 1026 635 23.59 22.95 15.28 28.09 30.11 31.64 20.60666667 29.94666667 1424 1491 1554 900.3333333 1489.666667 1.66E-08 0.725411187 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04934///Cushing syndrome+++04972///Pancreatic secretion+++05211///Renal cell carcinoma+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0007399///nervous system development+++GO:0009743///response to carbohydrate+++GO:0010976///positive regulation of neuron projection development+++GO:0032486///Rap protein signal transduction+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0035690///cellular response to drug+++GO:0038180///nerve growth factor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0046326///positive regulation of glucose import+++GO:0061028///establishment of endothelial barrier+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0071407///cellular response to organic cyclic compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0097327///response to antineoplastic agent+++GO:0097421///liver regeneration+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1901888///regulation of cell junction assembly+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000301///negative regulation of synaptic vesicle exocytosis+++GO:2001214///positive regulation of vasculogenesis 109910 109910 'Zfp91' mRNA 827 807 765 7.84 7.52 7.69 7.94 7.51 8.19 7.683333333 7.88 964 891 963 799.6666667 939.3333333 0.023512621 0.220727672 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070534///protein K63-linked ubiquitination 109929 109929 'Zbtb25' mRNA 608.64 549.05 576.88 6.85 6.14 6.05 4.02 3.91 3.83 6.346666667 3.92 704.47 664.47 709.53 578.19 692.8233333 0.031634455 0.248369335 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 109934 109934 'Abr' mRNA 2298 2347 1917 24.96 25.04 22.05 13.85 15.59 14.92 24.01666667 14.78666667 1457 1599 1534 2187.333333 1530 1.21E-10 -0.522722089 "GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0004674///protein serine/threonine kinase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0002692///negative regulation of cellular extravasation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007420///brain development+++GO:0030036///actin cytoskeleton organization+++GO:0030336///negative regulation of cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0035556///intracellular signal transduction+++GO:0042472///inner ear morphogenesis+++GO:0043114///regulation of vascular permeability+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0043547///positive regulation of GTPase activity+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050885///neuromuscular process controlling balance+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0090630///activation of GTPase activity 109978 109978 'Art4' mRNA 10 19 12 0.23 0.44 0.3 0.43 0.36 0.44 0.323333333 0.41 21 17 21 13.66666667 19.66666667 0.479190265 0.516758809 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006471///protein ADP-ribosylation+++GO:0018120///peptidyl-arginine ADP-ribosylation 109979 109979 'Art3' mRNA 2426 2384 2323 98.22 94.8 99.76 50.66 46.61 47.81 97.59333333 48.36 1448 1293 1316 2377.666667 1352.333333 8.81E-31 -0.826837353 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006471///protein ADP-ribosylation+++GO:0018120///peptidyl-arginine ADP-ribosylation 110006 110006 'Gusb' mRNA 1076.4 1161.58 1034.58 24.69 26.08 23.77 122.53 129.35 121.76 24.84666667 124.5466667 6203.37 6428.98 5893.14 1090.853333 6175.163333 0 2.491448286 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00531///Glycosaminoglycan degradation+++00860///Porphyrin metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04142///Lysosome GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004566///beta-glucuronidase activity+++GO:0005102///signaling receptor binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0019391///glucuronoside catabolic process 110012 110012 'Tpgs1' mRNA 733 771 715 42.96 44.66 44.46 52.63 53.56 51.06 44.02666667 52.41666667 1030 1022 966 739.6666667 1006 3.29E-06 0.432458365 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0070740///tubulin-glutamic acid ligase activity GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0018095///protein polyglutamylation+++GO:0030154///cell differentiation+++GO:0030534///adult behavior+++GO:0051648///vesicle localization 110033 110033 'Kif22' mRNA 18 12 14 0.49 0.3 0.41 8.93 8.24 8.42 0.4 8.53 374 337 342 14.66666667 351 1.36E-61 4.569000422 04914///Progesterone-mediated oocyte maturation GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0016607///nuclear speck+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0006281///DNA repair+++GO:0007018///microtubule-based movement+++GO:0007062///sister chromatid cohesion+++GO:0007080///mitotic metaphase plate congression+++GO:0051310///metaphase plate congression 110052 110052 'Dek' mRNA 1991.9 1955.69 1859.92 42.49 41.09 42.06 44.7 39.84 41.09 41.88 41.87666667 2410.35 2097.85 2146.17 1935.836667 2218.123333 0.01576513 0.184261064 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043292///contractile fiber GO:0003677///DNA binding+++GO:0042393///histone binding GO:0006325///chromatin organization+++GO:0044838///cell quiescence+++GO:2000779///regulation of double-strand break repair+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 110058 110058 'Syt17' mRNA 251.01 298 157.62 4.7 5.76 3.22 0.65 0.78 0.73 4.56 0.72 40 47 41.96 235.5433333 42.98666667 4.61E-21 -2.462471528 GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070382///exocytic vesicle GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding GO:0006887///exocytosis+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0030154///cell differentiation+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 110074 110074 'Dut' mRNA 482 529 500 11.75 12.75 12.96 11.93 12.75 12.57 12.48666667 12.41666667 561 588 572 503.6666667 573.6666667 0.169168234 0.176361804 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0004170///dUTP diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0030547///receptor inhibitor activity+++GO:0032556///pyrimidine deoxyribonucleotide binding+++GO:0042802///identical protein binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046872///metal ion binding GO:0001889///liver development+++GO:0006226///dUMP biosynthetic process+++GO:0006231///dTMP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0043254///regulation of protein complex assembly+++GO:0046081///dUTP catabolic process+++GO:2000272///negative regulation of signaling receptor activity 110075 110075 'Bmp3' mRNA 513 541 548 4.36 4.52 4.94 3.36 2.19 2.72 4.606666667 2.756666667 455 289 357 534 367 3.41E-04 -0.558222663 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031982///vesicle GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0070700///BMP receptor binding GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development+++GO:0060395///SMAD protein signal transduction 110078 110078 'Pygb' mRNA 8302 8728 8445 117.02 121.01 126.27 79.11 73.9 79.1 121.4333333 77.37 6460 5895 6255 8491.666667 6203.333333 2.33E-16 -0.466051553 00500///Starch and sucrose metabolism+++04217///Necroptosis+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance GO:0005737///cytoplasm+++GO:0030424///axon "GO:0003824///catalytic activity+++GO:0004645///phosphorylase activity+++GO:0008184///glycogen phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030170///pyridoxal phosphate binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0097159///organic cyclic compound binding+++GO:0102250///linear malto-oligosaccharide phosphorylase activity+++GO:0102499///SHG alpha-glucan phosphorylase activity" GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process+++GO:0008152///metabolic process 110082 110082 'Dnah5' mRNA 1018 1035 965 3.42 3.42 3.43 0.29 0.22 0.31 3.423333333 0.273333333 97 75 104 1006 92 1.38E-141 -3.46279531 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036157///outer dynein arm+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0007018///microtubule-based movement+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0021670///lateral ventricle development+++GO:0030317///flagellated sperm motility+++GO:0036158///outer dynein arm assembly+++GO:0051649///establishment of localization in cell+++GO:0060271///cilium assembly 110083 110083 'Dnah12' mRNA 1 3.76 2 0.01 0.02 0.01 0 0.01 0.02 0.013333333 0.01 1 2 4 2.253333333 2.333333333 0.918503569 0.218078793 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0016567///protein ubiquitination 110084 110084 'Dnah1' mRNA 62 114 61 0.25 0.45 0.26 0.09 0.08 0.09 0.32 0.086666667 27 21 26 79 24.66666667 1.52E-05 -1.683293316 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0007018///microtubule-based movement+++GO:0007288///sperm axoneme assembly+++GO:0030317///flagellated sperm motility+++GO:0036159///inner dynein arm assembly+++GO:0060294///cilium movement involved in cell motility 110094 110094 'Phka2' mRNA 3622.88 3515.01 3116.7 18.56 17.79 17 10.7 9.39 10.8 17.78333333 10.29666667 2397.71 1984.89 2329.79 3418.196667 2237.463333 4.17E-17 -0.62251959 04020///Calcium signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005886///plasma membrane+++GO:0005964///phosphorylase kinase complex+++GO:0016020///membrane GO:0005516///calmodulin binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006468///protein phosphorylation 110095 110095 'Pygl' mRNA 477 507 573 9.33 9.76 11.89 9.71 8.86 9.73 10.32666667 9.433333333 571 509 554 519 544.6666667 0.763426269 0.053042218 00500///Starch and sucrose metabolism+++04217///Necroptosis+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0002060///purine nucleobase binding+++GO:0003824///catalytic activity+++GO:0004645///phosphorylase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008184///glycogen phosphorylase activity+++GO:0016208///AMP binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019842///vitamin binding+++GO:0030170///pyridoxal phosphate binding+++GO:0030246///carbohydrate binding+++GO:0032052///bile acid binding+++GO:0042802///identical protein binding+++GO:0102250///linear malto-oligosaccharide phosphorylase activity+++GO:0102499///SHG alpha-glucan phosphorylase activity" GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process+++GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0008152///metabolic process+++GO:0009617///response to bacterium+++GO:0042593///glucose homeostasis+++GO:0070266///necroptotic process 110109 110109 'Nop2' mRNA 587 682 603 12.4 14.19 13.52 16.64 16.76 15.05 13.37 16.15 907 891 793 624 863.6666667 2.06E-05 0.457763852 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0009383///rRNA (cytosine-C5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0000027///ribosomal large subunit assembly+++GO:0000470///maturation of LSU-rRNA+++GO:0001510///RNA methylation+++GO:0001825///blastocyst formation+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0008284///positive regulation of cell proliferation+++GO:0032259///methylation+++GO:0042254///ribosome biogenesis+++GO:0070475///rRNA base methylation+++GO:1901796///regulation of signal transduction by p53 class mediator 110119 110119 'Mpi' mRNA 768.89 732.8 734.04 16.49 14.89 17.56 28.08 28.22 27.23 16.31333333 27.84333333 1312.79 1237.15 1141.28 745.2433333 1230.406667 1.19E-14 0.711312972 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004476///mannose-6-phosphate isomerase activity+++GO:0008270///zinc ion binding+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0000032///cell wall mannoprotein biosynthetic process+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0009298///GDP-mannose biosynthetic process+++GO:0061611///mannose to fructose-6-phosphate metabolic process+++GO:0061619///glycolytic process from mannose through fructose-6-phosphate 110147 110147 'Ehmt2' mRNA 1086.84 1076.04 947.46 14.87 14.3 13.75 12.67 12.85 13.49 14.30666667 13.00333333 1066.09 1060.01 1089.99 1036.78 1072.03 0.743984844 0.038860103 00310///Lysine degradation+++04211///Longevity regulating pathway GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0046976///histone methyltransferase activity (H3-K27 specific)+++GO:0070742///C2H2 zinc finger domain binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006275///regulation of DNA replication+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007130///synaptonemal complex assembly+++GO:0007281///germ cell development+++GO:0007286///spermatid development+++GO:0007616///long-term memory+++GO:0009267///cellular response to starvation+++GO:0009566///fertilization+++GO:0010424///DNA methylation on cytosine within a CG sequence+++GO:0016571///histone methylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0031667///response to nutrient levels+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0035265///organ growth+++GO:0035690///cellular response to drug+++GO:0036166///phenotypic switching+++GO:0044030///regulation of DNA methylation+++GO:0045471///response to ethanol+++GO:0048148///behavioral response to cocaine+++GO:0048665///neuron fate specification+++GO:0051567///histone H3-K9 methylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0051570///regulation of histone H3-K9 methylation+++GO:0060992///response to fungicide+++GO:0070734///histone H3-K27 methylation+++GO:0071314///cellular response to cocaine+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1902902///negative regulation of autophagosome assembly 110157 110157 'Raf1' mRNA 2433.95 2675.94 2698.4 43.68 47.13 51.13 36.83 37.54 35.18 47.31333333 36.51666667 2353.63 2320.72 2168.14 2602.763333 2280.83 0.014983372 -0.20426273 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04613///Neutrophil extracellular trap formation+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05132///Salmonella infection+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031143///pseudopodium GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008179///adenylate cyclase binding+++GO:0010856///adenylate cyclase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0001666///response to hypoxia+++GO:0001678///cellular glucose homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007190///activation of adenylate cyclase activity+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0030878///thyroid gland development+++GO:0031333///negative regulation of protein complex assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035019///somatic stem cell population maintenance+++GO:0035556///intracellular signal transduction+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0035994///response to muscle stretch+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048538///thymus development+++GO:0060324///face development+++GO:0071550///death-inducing signaling complex assembly+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 110168 110168 'Gpr18' mRNA 9 11 9 0.38 0.45 0.4 0.91 1.31 0.68 0.41 0.966666667 25 35 18 9.666666667 26 0.025993553 1.420000358 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0004930///G protein-coupled receptor activity "GO:0002300///CD8-positive, alpha-beta intraepithelial T cell differentiation+++GO:0002305///CD8-positive, gamma-delta intraepithelial T cell differentiation+++GO:0002689///negative regulation of leukocyte chemotaxis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway" 110172 110172 'Slc35b1' mRNA 1028 1088 1046 45.83 47.83 49.48 74.91 77.13 78.97 47.71333333 77.00333333 1935 1942 1972 1054 1949.666667 3.26E-30 0.875595464 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005459///UDP-galactose transmembrane transporter activity+++GO:0005460///UDP-glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0072334///UDP-galactose transmembrane transport 110173 110173 'Manba' mRNA 2416 2380 2444 35.63 34.52 38.23 22.43 22.31 23.72 36.12666667 22.82 1752 1701 1793 2413.333333 1748.666667 9.62E-11 -0.477936894 00511///Other glycan degradation+++04142///Lysosome GO:0005615///extracellular space+++GO:0005764///lysosome "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004567///beta-mannosidase activity+++GO:0005537///mannose binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0006516///glycoprotein catabolic process+++GO:0008152///metabolic process 110175 110175 'Ggct' mRNA 134 119 128 7.48 6.96 6.77 16.71 15.46 16.26 7.07 16.14333333 390 356 381 127 375.6666667 6.60E-22 1.551573961 00480///Glutathione metabolism GO:0005829///cytosol GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0016829///lyase activity+++GO:0042803///protein homodimerization activity GO:0001836///release of cytochrome c from mitochondria 110196 110196 'Fdps' mRNA 4310 4374 3862 209.37 210.01 199.02 69.01 64.99 68.56 206.1333333 67.52 1641 1504 1576 4182 1573.666667 1.13E-118 -1.420432013 00900///Terpenoid backbone biosynthesis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005777///peroxisome+++GO:0005829///cytosol GO:0004161///dimethylallyltranstransferase activity+++GO:0004337///geranyltranstransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0033384///geranyl diphosphate biosynthetic process+++GO:0045337///farnesyl diphosphate biosynthetic process+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development 110197 110197 'Dgkg' mRNA 545 523 582 4.7 4.48 5.39 0.91 1.16 0.96 4.856666667 1.01 124 146 129 550 133 1.98E-41 -2.061776154 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation+++GO:0048666///neuron development+++GO:0050773///regulation of dendrite development+++GO:0090038///negative regulation of protein kinase C signaling 110198 110198 'Akr7a5' mRNA 1229 1231 1164 43.48 42.93 43.68 41.16 42.43 42.32 43.36333333 41.97 1337 1345 1330 1208 1337.333333 0.121264228 0.135665893 00980///Metabolism of xenobiotics by cytochrome P450 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol "GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0016491///oxidoreductase activity+++GO:0019119///phenanthrene-9,10-epoxide hydrolase activity+++GO:0042802///identical protein binding+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process 110208 110208 'Pgd' mRNA 1765 1843 1704 44.92 46.2 45.99 99.89 94.31 101.43 45.70333333 98.54333333 4517 4164 4439 1770.666667 4373.333333 2.90E-100 1.292844261 00030///Pentose phosphate pathway+++00480///Glutathione metabolism+++01200///Carbon metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0004616///phosphogluconate dehydrogenase (decarboxylating) activity+++GO:0008114///phosphogluconate 2-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0030246///carbohydrate binding+++GO:0031406///carboxylic acid binding+++GO:0050661///NADP binding "GO:0005975///carbohydrate metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0006739///NADP metabolic process+++GO:0009051///pentose-phosphate shunt, oxidative branch+++GO:0019322///pentose biosynthetic process+++GO:0019521///D-gluconate metabolic process+++GO:0046177///D-gluconate catabolic process" 110213 110213 'Tmbim6' mRNA 20263 20987 21225 473.7 483.04 526.67 448.54 467.96 440.12 494.47 452.2066667 22050 22466 20952 20825 21822.66667 0.466576062 0.054251953 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0060698///endoribonuclease inhibitor activity GO:0002638///negative regulation of immunoglobulin production+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0010523///negative regulation of calcium ion transport into cytosol+++GO:0032091///negative regulation of protein binding+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0033119///negative regulation of RNA splicing+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043066///negative regulation of apoptotic process+++GO:0060702///negative regulation of endoribonuclease activity+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:1902065///response to L-glutamate+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:2001234///negative regulation of apoptotic signaling pathway 110253 110253 'Triobp' mRNA 7934.97 7894.62 6734.98 100.12 96.62 91.11 31.73 33.92 35.2 95.95 33.61666667 2158.27 2191.56 2263.01 7521.523333 2204.28 9.05E-188 -1.779115508 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030496///midbody+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0120043///stereocilium shaft+++GO:0120044///stereocilium base GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0007605///sensory perception of sound+++GO:0009790///embryo development+++GO:0051017///actin filament bundle assembly+++GO:0051301///cell division+++GO:0060088///auditory receptor cell stereocilium organization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 110257 110257 'Hba-a2' mRNA 441.69 453.66 381.91 61.98 63.48 56.89 70.5 89.21 76.39 60.78333333 78.7 572.59 703.74 597.55 425.7533333 624.6266667 2.52E-05 0.546926979 05143///African trypanosomiasis+++05144///Malaria GO:0005615///extracellular space+++GO:0005833///hemoglobin complex+++GO:0022627///cytosolic small ribosomal subunit+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0043209///myelin sheath GO:0005344///oxygen carrier activity+++GO:0005506///iron ion binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0043177///organic acid binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0009617///response to bacterium+++GO:0035634///response to stilbenoid+++GO:0042744///hydrogen peroxide catabolic process+++GO:0048821///erythrocyte development+++GO:0098869///cellular oxidant detoxification 110265 110265 'Msra' mRNA 370 325 320 16.39 14.1 15.04 13.86 13.63 14.9 15.17666667 14.13 367 346 371 338.3333333 361.3333333 0.641550165 0.083591636 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0008113///peptide-methionine (S)-S-oxide reductase activity+++GO:0016491///oxidoreductase activity+++GO:0033744///L-methionine:thioredoxin-disulfide S-oxidoreductase activity+++GO:0036456///L-methionine-(S)-S-oxide reductase activity GO:0007568///aging+++GO:0034599///cellular response to oxidative stress 110279 110279 'Bcr' mRNA 536 447 411 4.82 4.12 3.87 3.91 3.3 3.65 4.27 3.62 467 412 460 464.6666667 446.3333333 0.701236715 -0.068060812 05200///Pathways in cancer+++05220///Chronic myeloid leukemia "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding GO:0002692///negative regulation of cellular extravasation+++GO:0003014///renal system process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030216///keratinocyte differentiation+++GO:0030336///negative regulation of cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0042472///inner ear morphogenesis+++GO:0043114///regulation of vascular permeability+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0043547///positive regulation of GTPase activity+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048041///focal adhesion assembly+++GO:0048872///homeostasis of number of cells+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050885///neuromuscular process controlling balance+++GO:0051171///regulation of nitrogen compound metabolic process+++GO:0051726///regulation of cell cycle+++GO:0060216///definitive hemopoiesis+++GO:0060268///negative regulation of respiratory burst+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0065002///intracellular protein transmembrane transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090630///activation of GTPase activity+++GO:2000378///negative regulation of reactive oxygen species metabolic process 110304 110304 'Glra3' mRNA 366 385 303 2.95 3.06 2.59 1.08 1.03 1.17 2.866666667 1.093333333 154 144 162 351.3333333 153.3333333 7.30E-14 -1.204111314 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016935///glycine-gated chloride channel complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098690///glycinergic synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0016594///glycine binding+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0022824///transmitter-gated ion channel activity+++GO:0022852///glycine-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0046872///metal ion binding "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043200///response to amino acid+++GO:0050877///nervous system process+++GO:0051260///protein homooligomerization+++GO:0060012///synaptic transmission, glycinergic+++GO:0060079///excitatory postsynaptic potential+++GO:0071230///cellular response to amino acid stimulus+++GO:0071294///cellular response to zinc ion+++GO:0071361///cellular response to ethanol+++GO:0097688///glutamate receptor clustering+++GO:1902476///chloride transmembrane transport+++GO:2000300///regulation of synaptic vesicle exocytosis" 110308 110308 'Krt5' mRNA 6 10 9 0.15 0.25 0.24 0.73 0.43 0.46 0.213333333 0.54 33 19 20 8.333333333 24 0.024933808 1.507924261 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0045095///keratin filament GO:0005515///protein binding+++GO:0097110///scaffold protein binding 110310 110310 'Krt7' mRNA 528 607 574 19.51 22.12 22.5 83.98 85.37 80.42 21.37666667 83.25666667 2611 2590 2419 569.6666667 2540 6.67E-144 2.144530233 GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0005515///protein binding 110323 110323 'Cox6b1' mRNA 6119 5937 6187 1146.8 1115.13 1231.39 1126.78 1281.06 1210.52 1164.44 1206.12 6826 7523 7049 6081 7132.666667 0.002816118 0.217674962 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0045277///respiratory chain complex IV GO:0006119///oxidative phosphorylation 110326 110326 'Tas1r1' mRNA 251 267 257 4.58 4.97 5.14 0.66 0.9 0.8 4.896666667 0.786666667 38 53 45 258.3333333 45.33333333 1.33E-29 -2.521112351 04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008527///taste receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0050912///detection of chemical stimulus involved in sensory perception of taste+++GO:0050917///sensory perception of umami taste 110332 110332 'Pp2d1' mRNA 11.44 17.49 7.38 0.26 0.39 0.18 0.18 0.25 0.25 0.276666667 0.226666667 9.33 12.41 12.35 12.10333333 11.36333333 0.934402319 -0.081166269 GO:0004722///protein serine/threonine phosphatase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation 110350 110350 'Dync2h1' mRNA 1833.49 2030.77 1726.49 14.21 16.38 14.08 5.36 5.1 5.01 14.89 5.156666667 766.56 699.38 747.78 1863.583333 737.9066667 8.54E-62 -1.347432761 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0045177///apical part of cell "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0001822///kidney development+++GO:0007018///microtubule-based movement+++GO:0007030///Golgi organization+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0009953///dorsal/ventral pattern formation+++GO:0016485///protein processing+++GO:0021522///spinal cord motor neuron differentiation+++GO:0030030///cell projection organization+++GO:0030182///neuron differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030900///forebrain development+++GO:0035721///intraciliary retrograde transport+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060271///cilium assembly+++GO:0060976///coronary vasculature development+++GO:0061512///protein localization to cilium+++GO:1905515///non-motile cilium assembly 110351 110351 'Rap1gap' mRNA 890 939 769 14.82 15.3 13.56 10.35 10.22 9.88 14.56 10.15 722 698 663 866 694.3333333 0.001294776 -0.327594544 04015///Rap1 signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity GO:0022409///positive regulation of cell-cell adhesion+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045665///negative regulation of neuron differentiation+++GO:0050766///positive regulation of phagocytosis+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity+++GO:1903697///negative regulation of microvillus assembly+++GO:1904425///negative regulation of GTP binding+++GO:1904442///negative regulation of thyroid gland epithelial cell proliferation+++GO:1990792///cellular response to glial cell derived neurotrophic factor 110355 110355 'Grk2' mRNA 434 405 373 7 6.43 6.38 11.45 11.65 11.93 6.603333333 11.67666667 817 812 824 404 817.6666667 1.53E-21 1.007079314 04062///Chemokine signaling pathway+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04724///Glutamatergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++05032///Morphine addiction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031755///Edg-2 lysophosphatidic acid receptor binding+++GO:0031850///delta-type opioid receptor binding+++GO:0031851///kappa-type opioid receptor binding+++GO:0047696///beta-adrenergic receptor kinase activity+++GO:0097110///scaffold protein binding GO:0002026///regulation of the force of heart contraction+++GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0003108///negative regulation of the force of heart contraction by chemical signal+++GO:0006468///protein phosphorylation+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007217///tachykinin receptor signaling pathway+++GO:0007507///heart development+++GO:0009966///regulation of signal transduction+++GO:0010661///positive regulation of muscle cell apoptotic process+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0014070///response to organic cyclic compound+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019079///viral genome replication+++GO:0031623///receptor internalization+++GO:0032755///positive regulation of interleukin-6 production+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033605///positive regulation of catecholamine secretion+++GO:0042311///vasodilation+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045907///positive regulation of vasoconstriction+++GO:0045988///negative regulation of striated muscle contraction+++GO:0046325///negative regulation of glucose import+++GO:0046718///viral entry into host cell+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048709///oligodendrocyte differentiation+++GO:0051457///maintenance of protein location in nucleus+++GO:0060048///cardiac muscle contraction+++GO:0071333///cellular response to glucose stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1900077///negative regulation of cellular response to insulin stimulus+++GO:1901081///negative regulation of relaxation of smooth muscle+++GO:1904058///positive regulation of sensory perception of pain+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1990869///cellular response to chemokine+++GO:2000117///negative regulation of cysteine-type endopeptidase activity+++GO:2000463///positive regulation of excitatory postsynaptic potential 110379 110379 'Sec13' mRNA 2376 2244 2283 110.48 102.99 112.62 164.07 178.41 163.87 108.6966667 168.7833333 4051 4297 3913 2301 4087 2.54E-31 0.816871567 03013///Nucleocytoplasmic transport+++04141///Protein processing in endoplasmic reticulum+++04150///mTOR signaling pathway+++05014///Amyotrophic lateral sclerosis GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031080///nuclear pore outer ring+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0061700///GATOR2 complex GO:0005198///structural molecule activity+++GO:0042802///identical protein binding GO:0006606///protein import into nucleus+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032008///positive regulation of TOR signaling+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0051028///mRNA transport+++GO:0072659///protein localization to plasma membrane+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding+++GO:1904263///positive regulation of TORC1 signaling 110380 110380 'Shroom2' mRNA 791 819 812 7.41 7.83 8.9 7.15 6.54 7.75 8.046666667 7.146666667 785 703 812 807.3333333 766.6666667 0.483400072 -0.087705757 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0043025///neuronal cell body+++GO:0043296///apical junction complex GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019904///protein domain specific binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0008057///eye pigment granule organization+++GO:0016477///cell migration+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0032401///establishment of melanosome localization+++GO:0032438///melanosome organization+++GO:0043010///camera-type eye development+++GO:0043482///cellular pigment accumulation+++GO:0043583///ear development+++GO:0045176///apical protein localization+++GO:0045217///cell-cell junction maintenance+++GO:0048593///camera-type eye morphogenesis+++GO:0051017///actin filament bundle assembly 110385 110385 'Pde4c' mRNA 33.54 39.02 36.12 0.57 0.76 0.62 0.54 0.46 0.32 0.65 0.44 29.54 24.28 18.29 36.22666667 24.03666667 0.221267429 -0.619105653 "00230///Purine metabolism+++04024///cAMP signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05032///Morphine addiction" GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 110391 110391 'Qdpr' mRNA 2240 2456 2222 96.06 103.92 101.09 67.07 76.44 77.37 100.3566667 73.62666667 1796 1997 2004 2306 1932.333333 0.001264496 -0.264851835 00790///Folate biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043005///neuron projection "GO:0004155///6,7-dihydropteridine reductase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0070402///NADPH binding+++GO:0070404///NADH binding" GO:0001889///liver development+++GO:0006559///L-phenylalanine catabolic process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0010044///response to aluminum ion+++GO:0010288///response to lead ion+++GO:0033762///response to glucagon+++GO:0035690///cellular response to drug 110417 110417 'Pigh' mRNA 953.1 998.02 849.76 22.68 23.38 21.45 16.53 17.06 15.5 22.50333333 16.36333333 799.56 806.25 725.26 933.6266667 777.0233333 0.006224498 -0.274406182 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0006506///GPI anchor biosynthetic process 110446 110446 'Acat1' mRNA 2250 2203 2226 36.36 35.02 38.16 30.44 32.25 30.93 36.51333333 31.20666667 2168 2243 2133 2226.333333 2181.333333 0.666334817 -0.041733453 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00650///Butanoate metabolism+++00900///Terpenoid backbone biosynthesis+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++04975///Fat digestion and absorption" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016453///C-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0019899///enzyme binding+++GO:0030955///potassium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0001889///liver development+++GO:0006085///acetyl-CoA biosynthetic process+++GO:0006550///isoleucine catabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0007420///brain development+++GO:0009725///response to hormone+++GO:0014070///response to organic cyclic compound+++GO:0015936///coenzyme A metabolic process+++GO:0015937///coenzyme A biosynthetic process+++GO:0042594///response to starvation+++GO:0046356///acetyl-CoA catabolic process+++GO:0046952///ketone body catabolic process+++GO:0060612///adipose tissue development+++GO:0072229///metanephric proximal convoluted tubule development+++GO:1902860///propionyl-CoA biosynthetic process 110454 110454 'Ly6a' mRNA 2216.25 2391.75 2259.74 148.84 159.19 161.71 578.12 562.6 574.85 156.58 571.8566667 9927.12 9415.58 9529.21 2289.246667 9623.97 1.87E-295 2.059903548 GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0005515///protein binding+++GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0009617///response to bacterium+++GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 110460 110460 'Acat2' mRNA 1789.09 1972.92 1814.49 48.87 53.09 52.58 26.14 30.78 27.71 51.51333333 28.21 1100.26 1264.96 1129.12 1858.833333 1164.78 5.19E-15 -0.684711817 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00650///Butanoate metabolism+++00900///Terpenoid backbone biosynthesis+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++04975///Fat digestion and absorption" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0045797///positive regulation of intestinal cholesterol absorption 110521 110521 'Hivep1' mRNA 493 499 427 2.92 2.91 2.71 2.71 2.32 2.42 2.846666667 2.483333333 525 436 453 473 471.3333333 0.924011351 -0.015848456 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030509///BMP signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 110524 110524 'Dgkq' mRNA 399.88 478.08 480.81 4.67 5.51 5.94 4.45 4.19 4.64 5.373333333 4.426666667 439.8 403.03 442.61 452.9233333 428.48 0.585229702 -0.09423216 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0033613///activating transcription factor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043274///phospholipase binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0006111///regulation of gluconeogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010033///response to organic substance+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0015031///protein transport+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0033198///response to ATP+++GO:0035556///intracellular signal transduction+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051591///response to cAMP+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0070528///protein kinase C signaling+++GO:0090038///negative regulation of protein kinase C signaling+++GO:0090181///regulation of cholesterol metabolic process+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1903432///regulation of TORC1 signaling+++GO:2000064///regulation of cortisol biosynthetic process+++GO:2000182///regulation of progesterone biosynthetic process+++GO:2000370///positive regulation of clathrin-dependent endocytosis 110532 110532 'Adarb1' mRNA 335.52 432.99 353 1.96 2.47 1.87 1.18 1.36 1.29 2.1 1.276666667 263 298 268 373.8366667 276.3333333 0.00538893 -0.442912409 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006382///adenosine to inosine editing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0007274///neuromuscular synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0016553///base conversion or substitution editing+++GO:0016556///mRNA modification+++GO:0021610///facial nerve morphogenesis+++GO:0021618///hypoglossal nerve morphogenesis+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0030336///negative regulation of cell migration+++GO:0035264///multicellular organism growth+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045070///positive regulation of viral genome replication+++GO:0050685///positive regulation of mRNA processing+++GO:0050884///neuromuscular process controlling posture+++GO:0051726///regulation of cell cycle+++GO:0060384///innervation+++GO:0060415///muscle tissue morphogenesis+++GO:0061744///motor behavior+++GO:0097049///motor neuron apoptotic process 110542 110542 'Amhr2' mRNA 14 19 9 0.41 0.55 0.28 0.31 0.47 0.32 0.413333333 0.366666667 12 18 12 14 14 0.998591786 0.002497992 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0048179///activin receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005026///transforming growth factor beta receptor activity, type II+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017002///activin-activated receptor activity+++GO:0042562///hormone binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:1990272///anti-Mullerian hormone receptor activity" GO:0006468///protein phosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007548///sex differentiation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0016310///phosphorylation+++GO:0032924///activin receptor signaling pathway+++GO:0071363///cellular response to growth factor stimulus+++GO:1902613///negative regulation of anti-Mullerian hormone signaling pathway+++GO:1990262///anti-Mullerian hormone signaling pathway 110557 110557 'H2-Q6' mRNA 224.79 221.43 219.97 6.02 5.81 6.19 31.96 32.35 33.36 6.006666667 32.55666667 1378.52 1358.7 1393.07 222.0633333 1376.763333 4.50E-144 2.625027402 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 110558 110558 'H2-Q9' mRNA 176.26 158.86 180.34 7.83 6.83 8.54 42.81 37.41 40.97 7.733333333 40.39666667 1101.83 956.56 1026.77 171.82 1028.386667 2.97E-99 2.570205088 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0032398///MHC class Ib protein complex+++GO:0042612///MHC class I protein complex+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0042605///peptide antigen binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0032729///positive regulation of interferon-gamma production+++GO:0051607///defense response to virus+++GO:0071346///cellular response to interferon-gamma" 110593 110593 'Prdm2' mRNA 1231 1326 992 8.92 9.38 7.45 7.37 5.97 7.01 8.583333333 6.783333333 1211 942 1097.02 1183 1083.34 0.26667328 -0.135516628 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008168///methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0043565///sequence-specific DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008340///determination of adult lifespan+++GO:0010468///regulation of gene expression+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0032355///response to estradiol+++GO:0045944///positive regulation of transcription by RNA polymerase II 110595 110595 'Timp4' mRNA 17 13 16 0.32 0.24 0.32 0.23 0.22 0.17 0.293333333 0.206666667 14 13 10 15.33333333 12.33333333 0.703094826 -0.329470072 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030017///sarcomere+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0004857///enzyme inhibitor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008270///zinc ion binding+++GO:0030414///peptidase inhibitor activity+++GO:0046872///metal ion binding GO:0007219///Notch signaling pathway+++GO:0007417///central nervous system development+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0032496///response to lipopolysaccharide+++GO:0034097///response to cytokine+++GO:0042493///response to drug+++GO:0042698///ovulation cycle+++GO:0043434///response to peptide hormone+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis 110596 110596 'Arhgef28' mRNA 2378 2508 2361 25.44 26.76 26.53 5.47 6.08 5.93 26.24333333 5.826666667 614 662.58 636 2415.666667 637.5266667 1.68E-129 -1.933351128 05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003723///RNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030154///cell differentiation+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0060052///neurofilament cytoskeleton organization 110599566 110599566 'Eef1akmt4' mRNA 92.27 117 81 6.02 7.55 5.61 18.87 18.98 19.85 6.393333333 19.23333333 331.61 325 337 96.75666667 331.2033333 1.11E-22 1.768368681 GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity 110599584 110599584 'Eef1akmt4-ece2' mRNA 5.73 0 0 0.09 0 0 0.34 0 0 0.03 0.113333333 24.39 0 0 1.91 8.13 0.669541333 2.244837995 GO:0000139///Golgi membrane+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane GO:0004222///metalloendopeptidase activity+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0007420///brain development+++GO:0007507///heart development+++GO:0010002///cardioblast differentiation+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0018022///peptidyl-lysine methylation+++GO:0032259///methylation 110606 110606 'Fntb' mRNA 1852 1785 1537 40.45 38.17 35.57 23.79 24.21 21.92 38.06333333 23.30666667 1257 1252 1124 1724.666667 1211 5.50E-10 -0.519077023 00900///Terpenoid backbone biosynthesis GO:0005875///microtubule associated complex+++GO:0005965///protein farnesyltransferase complex GO:0003824///catalytic activity+++GO:0004311///farnesyltranstransferase activity+++GO:0004659///prenyltransferase activity+++GO:0004660///protein farnesyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008318///protein prenyltransferase activity+++GO:0016740///transferase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding "GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010035///response to inorganic substance+++GO:0014070///response to organic cyclic compound+++GO:0018342///protein prenylation+++GO:0018343///protein farnesylation+++GO:0034097///response to cytokine+++GO:0042060///wound healing+++GO:0045787///positive regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048145///regulation of fibroblast proliferation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process" 110611 110611 'Hdlbp' mRNA 3654 3730 3624 30.75 30.87 32.34 37.25 36.44 36.95 31.32 36.88 5100 4871 4897 3669.333333 4956 2.73E-13 0.421249252 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0034364///high-density lipoprotein particle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process 110616 110616 'Atxn3' mRNA 545.54 567.33 456.6 6.87 6.64 4.9 8.74 7.91 8.62 6.136666667 8.423333333 884.95 759.49 744.39 523.1566667 796.2766667 8.31E-08 0.596644322 04141///Protein processing in endoplasmic reticulum+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031966///mitochondrial membrane+++GO:0042405///nuclear inclusion body GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004407///histone deacetylase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0051117///ATPase binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0010810///regulation of cell-substrate adhesion+++GO:0016579///protein deubiquitination+++GO:0030036///actin cytoskeleton organization+++GO:0034605///cellular response to heat+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0035640///exploration behavior+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0070536///protein K63-linked deubiquitination+++GO:0070932///histone H3 deacetylation+++GO:0071108///protein K48-linked deubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:1904294///positive regulation of ERAD pathway+++GO:1904379///protein localization to cytosolic proteasome complex involved in ERAD pathway 110637 110637 'Grik4' mRNA 35 44 31 0.56 0.64 0.48 0.15 0.08 0.07 0.56 0.1 12 7 7 36.66666667 8.666666667 2.00E-04 -2.090976127 04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0038023///signaling receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential" 110639 110639 'Prps2' mRNA 460 515 496 6.69 7.56 7.66 11.68 9.89 12.51 7.303333333 11.36 918 760 945 490.3333333 874.3333333 1.13E-12 0.820789531 00030///Pentose phosphate pathway+++00230///Purine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019003///GDP binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046872///metal ion binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006167///AMP biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0019693///ribose phosphate metabolic process+++GO:0031100///animal organ regeneration+++GO:0044249///cellular biosynthetic process 110648 110648 'Lmx1a' mRNA 965 940 804 15.26 14.61 13.61 8.28 7.14 8.83 14.49333333 8.083333333 596 505 614 903 571.6666667 4.29E-10 -0.669310003 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001558///regulation of cell growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0010468///regulation of gene expression+++GO:0021542///dentate gyrus development+++GO:0021549///cerebellum development+++GO:0021766///hippocampus development+++GO:0021953///central nervous system neuron differentiation+++GO:0030182///neuron differentiation+++GO:0030901///midbrain development+++GO:0042048///olfactory behavior+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050808///synapse organization+++GO:0071542///dopaminergic neuron differentiation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation" 110651 110651 'Rps6ka3' mRNA 177 173 150 1.32 1.29 1.19 2.59 1.9 3.01 1.266666667 2.5 404 287 452 166.6666667 381 1.06E-10 1.181538728 04010///MAPK signaling pathway+++04114///Oocyte meiosis+++04150///mTOR signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04931///Insulin resistance+++05135///Yersinia infection+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0002224///toll-like receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0035556///intracellular signal transduction+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II 110695 110695 'Aldh7a1' mRNA 2261 2223 2125 41.43 40.28 41.52 65.43 64.75 65.68 41.07666667 65.28666667 4047.76 3916.77 3939 2203 3967.843333 2.11E-45 0.837195491 "00010///Glycolysis / Gluconeogenesis+++00053///Ascorbate and aldarate metabolism+++00071///Fatty acid degradation+++00260///Glycine, serine and threonine metabolism+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++04936///Alcoholic liver disease" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004043///L-aminoadipate-semialdehyde dehydrogenase activity+++GO:0008802///betaine-aldehyde dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0019285///glycine betaine biosynthetic process from choline 110749 110749 'Chaf1b' mRNA 16 22 16 0.48 0.65 0.52 7.03 6.59 5.99 0.55 6.536666667 269 248 223 18 246.6666667 1.99E-41 3.766067812 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0033186///CAF-1 complex GO:0005515///protein binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031497///chromatin assembly 110750 110750 'Cse1l' mRNA 1251 1341 1444 18.84 19.87 23.07 18.93 19.23 19.15 20.59333333 19.10333333 1446 1435 1417 1345.333333 1432.666667 0.515225421 0.075786693 03013///Nucleocytoplasmic transport+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005049///nuclear export signal receptor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport 110751 110751 'Adam33' mRNA 40 48 36 0.48 0.7 0.47 1.23 1.37 1.54 0.55 1.38 110 117 138 41.33333333 121.6666667 5.41E-08 1.550236354 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001817///regulation of cytokine production+++GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0042127///regulation of cell proliferation 110784 110784 'Nr3c2' mRNA 1663 1677 1324 21.3 20.64 17.93 6.98 7.99 6.31 19.95666667 7.093333333 617 657 539 1554.666667 604.3333333 2.11E-41 -1.370007184 04960///Aldosterone-regulated sodium reabsorption "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006883///cellular sodium ion homeostasis+++GO:0007588///excretion+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000300///regulation of synaptic vesicle exocytosis" 110789 110789 'Adgrv1' mRNA 698 725 574 1.87 1.91 1.65 0.29 0.25 0.25 1.81 0.263333333 121 103 96 665.6666667 106.6666667 5.23E-72 -2.650352083 GO:0001917///photoreceptor inner segment+++GO:0002141///stereocilia ankle link+++GO:0002142///stereocilia ankle link complex+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060171///stereocilium membrane+++GO:1990075///periciliary membrane compartment+++GO:1990696///USH2 complex GO:0001965///G-protein alpha-subunit binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0010855///adenylate cyclase inhibitor activity+++GO:0016787///hydrolase activity+++GO:0017022///myosin binding GO:0007154///cell communication+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0030501///positive regulation of bone mineralization+++GO:0031647///regulation of protein stability+++GO:0045184///establishment of protein localization+++GO:0045494///photoreceptor cell maintenance+++GO:0048496///maintenance of animal organ identity+++GO:0048839///inner ear development+++GO:0050877///nervous system process+++GO:0050896///response to stimulus+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0050953///sensory perception of light stimulus+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0071277///cellular response to calcium ion+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0097264///self proteolysis+++GO:0098609///cell-cell adhesion 110794 110794 'Cebpe' mRNA 4 2 1 0.2 0.1 0.05 0.17 0.31 0.36 0.116666667 0.28 4 7 8 2.333333333 6.333333333 0.297482578 1.445514544 05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001816///cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006909///phagocytosis+++GO:0010628///positive regulation of gene expression+++GO:0030099///myeloid cell differentiation+++GO:0030225///macrophage differentiation+++GO:0030851///granulocyte differentiation+++GO:0042742///defense response to bacterium+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071222///cellular response to lipopolysaccharide" 110796 110796 'Tshz1' mRNA 488 556 477 5.47 6.1 5.63 4.32 3.9 3.88 5.733333333 4.033333333 446 388 387 507 407 0.011643595 -0.32821481 04391///Hippo signaling pathway - fly GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0042474///middle ear morphogenesis+++GO:0060023///soft palate development 110809 110809 'Srsf1' mRNA 1436 1452 981 13.92 13.84 10.07 10.03 10.05 10.35 12.61 10.14333333 1188 1162 1185 1289.666667 1178.333333 0.300982516 -0.134015078 03040///Spliceosome+++04657///IL-17 signaling pathway+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0043422///protein kinase B binding+++GO:0044547///DNA topoisomerase binding+++GO:0050733///RS domain binding+++GO:0098772///molecular function regulator "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000395///mRNA 5'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0033120///positive regulation of RNA splicing+++GO:0034504///protein localization to nucleus+++GO:0048255///mRNA stabilization+++GO:0048709///oligodendrocyte differentiation+++GO:0051028///mRNA transport+++GO:0060048///cardiac muscle contraction+++GO:0097398///cellular response to interleukin-17+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0097421///liver regeneration+++GO:0110012///protein localization to P-body" 110816 110816 'Pwp2' mRNA 324 302 316 4.53 4.15 4.68 4.79 5.45 4.9 4.453333333 5.046666667 395 439 391 314 408.3333333 0.012182092 0.367141109 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome "GO:0000028///ribosomal small subunit assembly+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 110821 110821 'Pcca' mRNA 1456 1560 1532 31.62 33.41 35.11 26.35 27.93 26.2 33.38 26.82666667 1399 1447 1350 1516 1398.666667 0.169801597 -0.128609522 "00280///Valine, leucine and isoleucine degradation+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004658///propionyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0016421///CoA carboxylase activity+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process 110826 110826 'Etfb' mRNA 3193 3142 3244 231.87 225.86 249.98 253.73 279.67 253.93 235.9033333 262.4433333 4003 4299 3870 3193 4057.333333 7.19E-06 0.332985587 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0017133///mitochondrial electron transfer flavoprotein complex GO:0000166///nucleotide binding+++GO:0009055///electron transfer activity GO:0022900///electron transport chain+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase 110829 110829 'Lims1' mRNA 1566.18 1652.49 1493.54 18.8 19.65 19.2 31.13 26.77 29.63 19.21666667 29.17666667 2908.02 2461.06 2695.16 1570.736667 2688.08 5.95E-26 0.763449899 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0007160///cell-matrix adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0010628///positive regulation of gene expression+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0043009///chordate embryonic development+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045184///establishment of protein localization+++GO:0045216///cell-cell junction organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0098609///cell-cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:2001046///positive regulation of integrin-mediated signaling pathway" 110834 110834 'Chrna3' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse+++GO:0098981///cholinergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0044877///protein-containing complex binding+++GO:1901363///heterocyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006937///regulation of muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007399///nervous system development+++GO:0007626///locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0014056///regulation of acetylcholine secretion, neurotransmission+++GO:0034220///ion transmembrane transport+++GO:0035095///behavioral response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0042493///response to drug+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060084///synaptic transmission involved in micturition+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1905144///response to acetylcholine+++GO:2000300///regulation of synaptic vesicle exocytosis" 110835 110835 'Chrna5' mRNA 2 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0044877///protein-containing complex binding "GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035095///behavioral response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:2000300///regulation of synaptic vesicle exocytosis" 110842 110842 'Etfa' mRNA 2269.03 2310.4 2250.16 83.18 82.95 87.6 96.61 101.22 93.36 84.57666667 97.06333333 2904.85 2984.74 2709.88 2276.53 2866.49 7.97E-06 0.320267346 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0017133///mitochondrial electron transfer flavoprotein complex GO:0005515///protein binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0022900///electron transport chain+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase 110854 110854 'Ptpa' mRNA 3261 3347 3089 70.33 71.09 70.7 74.63 73.32 79.24 70.70666667 75.73 3979 3818 4090 3232.333333 3962.333333 2.77E-06 0.282742951 04931///Insulin resistance+++05415///Diabetic cardiomyopathy GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0034704///calcium channel complex GO:0000166///nucleotide binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0008160///protein tyrosine phosphatase activator activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0019211///phosphatase activator activity+++GO:0019888///protein phosphatase regulator activity+++GO:0042803///protein homodimerization activity+++GO:0051721///protein phosphatase 2A binding GO:0007052///mitotic spindle organization+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity 110855 110855 'Pde6c' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00230///Purine metabolism GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030553///cGMP binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" "GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0007603///phototransduction, visible light+++GO:0046549///retinal cone cell development+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus" 110862 110862 'Kcnq3' mRNA 136.84 131.99 110.3 0.64 0.57 0.52 0.12 0.07 0.07 0.576666667 0.086666667 30.34 16.7 17.83 126.3766667 21.62333333 2.97E-15 -2.593202815 04725///Cholinergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0033268///node of Ranvier+++GO:0036477///somatodendritic compartment+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0045121///membrane raft GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044325///ion channel binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0071242///cellular response to ammonium ion+++GO:0071805///potassium ion transmembrane transport 110876 110876 'Scn2a' mRNA 50 62 61 0.3 0.36 0.39 0.2 0.17 0.15 0.35 0.173333333 39 32 27 57.66666667 32.66666667 0.033048961 -0.835473242 04742///Taste transduction GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0031226///intrinsic component of plasma membrane+++GO:0033268///node of Ranvier+++GO:0033270///paranode region of axon+++GO:0034706///sodium channel complex+++GO:0043005///neuron projection+++GO:0043194///axon initial segment+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0031402///sodium ion binding+++GO:0043522///leucine zipper domain binding+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007399///nervous system development+++GO:0007613///memory+++GO:0008627///intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051402///neuron apoptotic process+++GO:0055085///transmembrane transport+++GO:0071456///cellular response to hypoxia+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport+++GO:0099505///regulation of presynaptic membrane potential 110877 110877 'Slc18a1' mRNA 314.95 314.79 278.07 2.33 2.52 2.29 1.6 1.64 1.81 2.38 1.683333333 289.62 266.7 295.18 302.6033333 283.8333333 0.581588207 -0.102322897 04721///Synaptic vesicle cycle+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043195///terminal bouton+++GO:0045202///synapse GO:0005335///serotonin:sodium symporter activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0022857///transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity GO:0006836///neurotransmitter transport+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0015842///aminergic neurotransmitter loading into synaptic vesicle+++GO:0033603///positive regulation of dopamine secretion+++GO:0042908///xenobiotic transport+++GO:0051610///serotonin uptake+++GO:0051612///negative regulation of serotonin uptake+++GO:0055085///transmembrane transport 110880 110880 'Scn4a' mRNA 2 5 5 0.01 0.03 0.03 0 0.03 0.02 0.023333333 0.016666667 0 4 4 4 2.666666667 0.754095254 -0.590831245 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0015871///choline transport+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport+++GO:0100001///regulation of skeletal muscle contraction by action potential 110886 110886 'Gabra5' mRNA 3 8 1 0.05 0.13 0.02 0 0.06 0 0.066666667 0.02 0 3 0 4 1 0.354327764 -1.965940817 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0050811///GABA receptor binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001662///behavioral fear response+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007420///brain development+++GO:0007605///sensory perception of sound+++GO:0008306///associative learning+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048666///neuron development+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060119///inner ear receptor cell development+++GO:0060384///innervation+++GO:0090102///cochlea development+++GO:1902476///chloride transmembrane transport" 110891 110891 'Slc8a2' mRNA 96 89 104 0.84 0.79 1.02 0.16 0.21 0.17 0.883333333 0.18 23 27 19 96.33333333 23 1.08E-09 -2.081218735 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04740///Olfactory transduction+++04961///Endocrine and other factor-regulated calcium reabsorption+++04974///Protein digestion and absorption+++04978///Mineral absorption+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032592///integral component of mitochondrial membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0099055///integral component of postsynaptic membrane GO:0005432///calcium:sodium antiporter activity+++GO:0005516///calmodulin binding+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015491///cation:cation antiporter activity+++GO:0046872///metal ion binding+++GO:1905060///calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration GO:0002931///response to ischemia+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007154///cell communication+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0010468///regulation of gene expression+++GO:0030001///metal ion transport+++GO:0035725///sodium ion transmembrane transport+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050808///synapse organization+++GO:0050890///cognition+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0060291///long-term synaptic potentiation+++GO:0060402///calcium ion transport into cytosol+++GO:0070050///neuron cellular homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0098703///calcium ion import across plasma membrane+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0099608///regulation of action potential firing pattern+++GO:0106056///regulation of calcineurin-mediated signaling+++GO:1990034///calcium ion export across plasma membrane 110893 110893 'Slc8a3' mRNA 30 31 13 0.4 0.35 0.16 0.34 0.39 0.32 0.303333333 0.35 21 27 19 24.66666667 22.33333333 0.862844268 -0.138869495 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04740///Olfactory transduction+++04961///Endocrine and other factor-regulated calcium reabsorption+++04974///Protein digestion and absorption+++04978///Mineral absorption+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016528///sarcoplasm+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0031594///neuromuscular junction+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:0099055///integral component of postsynaptic membrane GO:0005432///calcium:sodium antiporter activity+++GO:0005516///calmodulin binding+++GO:0015297///antiporter activity+++GO:0015368///calcium:cation antiporter activity+++GO:0015491///cation:cation antiporter activity+++GO:0046872///metal ion binding+++GO:0099580///ion antiporter activity involved in regulation of postsynaptic membrane potential+++GO:1905060///calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007154///cell communication+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0014819///regulation of skeletal muscle contraction+++GO:0021537///telencephalon development+++GO:0030001///metal ion transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042552///myelination+++GO:0048709///oligodendrocyte differentiation+++GO:0050808///synapse organization+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060291///long-term synaptic potentiation+++GO:0060402///calcium ion transport into cytosol+++GO:0070588///calcium ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071456///cellular response to hypoxia+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0098703///calcium ion import across plasma membrane+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1990034///calcium ion export across plasma membrane 110895 110895 'Slc9a4' mRNA 230 165 249 3.28 2.3 3.97 5.43 4.88 5.03 3.183333333 5.113333333 435 380 389 214.6666667 401.3333333 7.87E-07 0.883115242 04971///Gastric acid secretion GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0001696///gastric acid secretion+++GO:0002064///epithelial cell development+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0009651///response to salt stress+++GO:0051453///regulation of intracellular pH+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 110902 110902 'Chrna2' mRNA 2 4 1 0.03 0.06 0.02 0.05 0.03 0.04 0.036666667 0.04 4 2 3 2.333333333 3 0.863090843 0.363807054 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0071944///cell periphery GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity "GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential" 110911 110911 'Cds2' mRNA 2399 2407 1747 18.41 16.76 13.17 11.59 12 11.39 16.11333333 11.66 1881 1852 1684 2184.333333 1805.666667 0.004834157 -0.279988991 00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0016779///nucleotidyltransferase activity" GO:0006629///lipid metabolic process+++GO:0007602///phototransduction+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0070085///glycosylation+++GO:0140042///lipid droplet formation 110920 110920 'Hspa13' mRNA 669 705 665 8.95 9.27 9.43 14.5 13.15 14.17 9.216666667 13.94 1250 1115 1182 679.6666667 1182.333333 2.04E-18 0.786391098 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0031072///heat shock protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0051085///chaperone cofactor-dependent protein refolding 110935 110935 'Atp6v1b1' mRNA 2 1 1 0.06 0.03 0.03 0.08 0.03 0.03 0.04 0.046666667 3 1 1 1.333333333 1.666666667 0.901199684 0.304854834 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0098850///extrinsic component of synaptic vesicle membrane" GO:0005524///ATP binding+++GO:0015078///proton transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding GO:0001503///ossification+++GO:0003091///renal water homeostasis+++GO:0003096///renal sodium ion transport+++GO:0006693///prostaglandin metabolic process+++GO:0006811///ion transport+++GO:0006885///regulation of pH+++GO:0007588///excretion+++GO:0007605///sensory perception of sound+++GO:0010468///regulation of gene expression+++GO:0030534///adult behavior+++GO:0035812///renal sodium excretion+++GO:0042048///olfactory behavior+++GO:0042472///inner ear morphogenesis+++GO:0045851///pH reduction+++GO:0046034///ATP metabolic process+++GO:0055064///chloride ion homeostasis+++GO:0055074///calcium ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:1902600///proton transmembrane transport 110948 110948 'Hlcs' mRNA 420.78 453.83 431.47 4.32 4.58 4.66 3.13 3.57 3.15 4.52 3.283333333 348.93 372.81 339.07 435.36 353.6033333 0.024738644 -0.31164737 00780///Biotin metabolism GO:0000785///chromatin+++GO:0005652///nuclear lamina+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004077///biotin-[acetyl-CoA-carboxylase] ligase activity+++GO:0004078///biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity+++GO:0004079///biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity+++GO:0004080///biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity+++GO:0005524///ATP binding+++GO:0009374///biotin binding+++GO:0016874///ligase activity+++GO:0018271///biotin-protein ligase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding GO:0006464///cellular protein modification process+++GO:0008152///metabolic process+++GO:0009305///protein biotinylation+++GO:0016570///histone modification+++GO:0070781///response to biotin+++GO:0071110///histone biotinylation 110954 110954 'Rpl10' mRNA 6732 6763 6463 578.03 575.64 588.91 910.31 916.61 936.81 580.86 921.2433333 12134 11897 12055.81 6652.666667 12028.93667 1.83E-66 0.842863771 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016021///integral component of membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0045182///translation regulator activity GO:0000027///ribosomal large subunit assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0043066///negative regulation of apoptotic process+++GO:1990403///embryonic brain development 110956 110956 'D17H6S56E-5' mRNA 174.66 141 123.05 2.86 2.28 2.14 19.04 19.41 17.49 2.426666667 18.64666667 1328.09 1319.72 1167.01 146.2366667 1271.606667 2.57E-137 3.113226668 GO:0016020///membrane+++GO:0016021///integral component of membrane 110957 110957 'D1Pas1' mRNA 0 1 0 0 0.02 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04622///RIG-I-like receptor signaling pathway+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0022627///cytosolic small ribosomal subunit+++GO:0031252///cell leading edge+++GO:0043186///P granule GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003729///mRNA binding+++GO:0003924///GTPase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008143///poly(A) binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0031369///translation initiation factor binding+++GO:0033592///RNA strand annealing activity+++GO:0035613///RNA stem-loop binding+++GO:0043015///gamma-tubulin binding+++GO:0043024///ribosomal small subunit binding+++GO:0043273///CTPase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0048027///mRNA 5'-UTR binding GO:0000239///pachytene+++GO:0006413///translational initiation+++GO:0007059///chromosome segregation+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0009615///response to virus+++GO:0010501///RNA secondary structure unwinding+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0031333///negative regulation of protein complex assembly+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032508///DNA duplex unwinding+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0034063///stress granule assembly+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034161///positive regulation of toll-like receptor 8 signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0042256///mature ribosome assembly+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045948///positive regulation of translational initiation+++GO:0055088///lipid homeostasis+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071470///cellular response to osmotic stress+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0098586///cellular response to virus+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901985///positive regulation of protein acetylation+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902523///positive regulation of protein K63-linked ubiquitination+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 110958 110958 'M1ap' mRNA 37 61 58 1.21 2.04 2.12 1.19 0.67 1.12 1.79 0.993333333 31 22 33 52 28.66666667 0.044143855 -0.875829951 GO:0005737///cytoplasm+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0042802///identical protein binding GO:0006396///RNA processing+++GO:0007127///meiosis I+++GO:0007283///spermatogenesis+++GO:0007292///female gamete generation+++GO:0030154///cell differentiation+++GO:0031497///chromatin assembly+++GO:0051308///male meiosis chromosome separation 110959 110959 'Nudt19' mRNA 517 549 470 15.38 16.1 14.84 21.79 22.88 22.12 15.44 22.26333333 842 863 827 512 844 2.37E-12 0.71172747 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0015938///coenzyme A catabolic process+++GO:0036114///medium-chain fatty-acyl-CoA catabolic process+++GO:0044580///butyryl-CoA catabolic process+++GO:1901289///succinyl-CoA catabolic process+++GO:1902858///propionyl-CoA metabolic process+++GO:2001294///malonyl-CoA catabolic process 110960 110960 'Tars' mRNA 892 887 945 18.77 18.37 21.09 25.79 26.58 25.79 19.41 26.05333333 1410 1419 1365 908 1398 1.43E-11 0.608929468 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004829///threonine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006435///threonyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation 110962 110962 'Mbd6' mRNA 1081 958 422 14.02 12.1 5.82 5.2 5 5.26 10.64666667 5.153333333 466 430 453 820.3333333 449.6666667 0.034263783 -0.861535006 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0010369///chromocenter GO:0003677///DNA binding+++GO:0003682///chromatin binding GO:0008150///biological_process 111173 111173 'Erc1' mRNA 2331.29 2289.68 2267.1 23.61 22.4 23.41 16.38 15.47 17.11 23.14 16.32 1907.66 1722.54 1835.43 2296.023333 1821.876667 1.35E-06 -0.34683264 04064///NF-kappa B signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0008385///IkappaB kinase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0031267///small GTPase binding+++GO:0098882///structural constituent of presynaptic active zone+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels "GO:0007252///I-kappaB phosphorylation+++GO:0007274///neuromuscular synaptic transmission+++GO:0015031///protein transport+++GO:0016082///synaptic vesicle priming+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048167///regulation of synaptic plasticity+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration" 111175 111175 'Pecr' mRNA 332 397 329 17.59 20.46 18.36 12.76 14.6 12.89 18.80333333 13.41666667 280 313 275 352.6666667 289.3333333 0.066073734 -0.294418138 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005102///signaling receptor binding+++GO:0016491///oxidoreductase activity+++GO:0019166///trans-2-enoyl-CoA reductase (NADPH) activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0033306///phytol metabolic process 111241 111241 'Hmga1b' mRNA 1237.32 1171.92 900.36 45.83 42.69 35.24 61.07 70.42 64.81 41.25333333 65.43333333 1898.91 2131.54 1941.38 1103.2 1990.61 4.88E-18 0.846715891 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0035985///senescence-associated heterochromatin focus+++GO:0090575///RNA polymerase II transcription factor complex GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0030527///structural constituent of chromatin+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity "GO:0006284///base-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090402///oncogene-induced cell senescence+++GO:2000774///positive regulation of cellular senescence" 112403 112403 'Dxo' mRNA 654 664 586 25.66 25.98 24.58 24.81 25.73 23.47 25.40666667 24.67 714 731 658 634.6666667 701 0.265721629 0.133657464 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0034353///RNA pyrophosphohydrolase activity+++GO:0046872///metal ion binding GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006402///mRNA catabolic process+++GO:0050779///RNA destabilization+++GO:0071028///nuclear mRNA surveillance+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 112405 112405 'Egln1' mRNA 439 455 490 6.85 6.94 8.07 7.31 6.64 7.89 7.286666667 7.28 540 484 566 461.3333333 530 0.19659863 0.18528166 04066///HIF-1 signaling pathway+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse "GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0019899///enzyme binding+++GO:0031418///L-ascorbic acid binding+++GO:0031543///peptidyl-proline dioxygenase activity+++GO:0031545///peptidyl-proline 4-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" "GO:0001666///response to hypoxia+++GO:0006879///cellular iron ion homeostasis+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0032364///oxygen homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045765///regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060347///heart trabecula formation+++GO:0060412///ventricular septum morphogenesis+++GO:0060711///labyrinthine layer development+++GO:0071456///cellular response to hypoxia+++GO:0071731///response to nitric oxide+++GO:0099175///regulation of postsynapse organization+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1901214///regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1905290///negative regulation of CAMKK-AMPK signaling cascade" 112406 112406 'Egln2' mRNA 2977 2971 2905 80.41 79.59 83.51 59.26 56.66 54.03 81.17 56.65 2495 2363 2218 2951 2358.666667 1.14E-06 -0.335852421 04066///HIF-1 signaling pathway+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0019826///oxygen sensor activity+++GO:0031418///L-ascorbic acid binding+++GO:0031543///peptidyl-proline dioxygenase activity+++GO:0031545///peptidyl-proline 4-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001666///response to hypoxia+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0043523///regulation of neuron apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0045732///positive regulation of protein catabolic process+++GO:0071456///cellular response to hypoxia 112407 112407 'Egln3' mRNA 252 290 249 5.13 5.81 5.33 2.98 2.94 2.32 5.423333333 2.746666667 169 161 126 263.6666667 152 1.31E-05 -0.805602368 04066///HIF-1 signaling pathway+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0031418///L-ascorbic acid binding+++GO:0031543///peptidyl-proline dioxygenase activity+++GO:0031545///peptidyl-proline 4-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001666///response to hypoxia+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0018126///protein hydroxylation+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0042127///regulation of cell proliferation+++GO:0043523///regulation of neuron apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:1990830///cellular response to leukemia inhibitory factor 112415 112415 'Zfp607b' mRNA 222.42 255.4 205.25 2.25 2.57 2.27 1.3 1.29 1.4 2.363333333 1.33 142.77 142.84 152.06 227.69 145.89 4.68E-04 -0.654063902 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 112418 112418 '1700102P08Rik' mRNA 26 19 14 0.77 0.55 0.49 0.21 0.41 0.26 0.603333333 0.293333333 8 11 8 19.66666667 9 0.115080768 -1.129840042 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 112419 112419 'Ifit1bl2' mRNA 113.46 110.21 104.51 1.88 1.84 1.83 2.12 2.31 1.66 1.85 2.03 143.63 154.83 108.94 109.3933333 135.8 0.26667328 0.297824574 05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding GO:0009615///response to virus+++GO:0050688///regulation of defense response to virus+++GO:0051607///defense response to virus+++GO:0071357///cellular response to type I interferon+++GO:0071360///cellular response to exogenous dsRNA 112422 112422 'Zfp979' mRNA 92.88 45.2 74.51 2.02 0.96 1.72 1.58 1.77 1.48 1.566666667 1.61 83.65 91.54 76.15 70.86333333 83.78 0.570018232 0.229352867 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 112694759 112694759 'Gm20517' mRNA 3.38 1.62 8.15 0.26 0.12 0.67 1.4 0.47 0.75 0.35 0.873333333 20.87 6.77 10.79 4.383333333 12.81 0.158765785 1.534790066 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0035914///skeletal muscle cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated" 11287 11287 'Pzp' mRNA 9 5 2 0.1 0.06 0.02 0 0.02 0 0.06 0.006666667 0 2 0 5.333333333 0.666666667 0.117888681 -2.981247775 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0019899///enzyme binding+++GO:0019959///interleukin-8 binding+++GO:0019966///interleukin-1 binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0043120///tumor necrosis factor binding+++GO:0044877///protein-containing complex binding+++GO:0048306///calcium-dependent protein binding+++GO:0048403///brain-derived neurotrophic factor binding+++GO:0048406///nerve growth factor binding "GO:0001869///negative regulation of complement activation, lectin pathway+++GO:0007565///female pregnancy+++GO:0007566///embryo implantation+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0048863///stem cell differentiation" 11298 11298 'Aanat' mRNA 0 0 2 0 0 0.04 0.02 0.05 0.13 0.013333333 0.066666667 1 3 4 0.666666667 2.666666667 0.434527303 1.95097523 00380///Tryptophan metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm "GO:0004059///aralkylamine N-acetyltransferase activity+++GO:0004060///arylamine N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0071889///14-3-3 protein binding" GO:0006474///N-terminal protein amino acid acetylation+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0009648///photoperiodism+++GO:0010043///response to zinc ion+++GO:0014070///response to organic cyclic compound+++GO:0030187///melatonin biosynthetic process+++GO:0032868///response to insulin+++GO:0034097///response to cytokine+++GO:0034695///response to prostaglandin E+++GO:0046688///response to copper ion+++GO:0048511///rhythmic process+++GO:0051412///response to corticosterone+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0071320///cellular response to cAMP+++GO:1901652///response to peptide 113002583 113002583 'Shld3' mRNA 38.34 52.81 54.91 1.37 1.87 2.09 2.2 1.81 2.25 1.776666667 2.086666667 70.67 56.76 69.95 48.68666667 65.79333333 0.2718279 0.420806399 GO:0005694///chromosome+++GO:0035861///site of double-strand break GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0045830///positive regulation of isotype switching+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 11302 11302 'Aatk' mRNA 4675 4773 4443 48.5 48.94 49.14 27.71 24.96 25.3 48.86 25.99 3053 2687 2699 4630.333333 2813 1.22E-32 -0.731258385 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007420///brain development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030517///negative regulation of axon extension+++GO:0032482///Rab protein signal transduction+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0046777///protein autophosphorylation+++GO:0051402///neuron apoptotic process 11303 11303 'Abca1' mRNA 1778 1729 1669 9.06 8.66 9.02 27.83 25.51 28.25 8.913333333 27.19666667 6289 5632 6184 1725.333333 6035 4.85E-186 1.794263056 02010///ABC transporters+++04975///Fat digestion and absorption+++04979///Cholesterol metabolism+++05417///Lipid and atherosclerosis GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097708///intracellular vesicle "GO:0000166///nucleotide binding+++GO:0005102///signaling receptor binding+++GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005548///phospholipid transporter activity+++GO:0008035///high-density lipoprotein particle binding+++GO:0008320///protein transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0019905///syntaxin binding+++GO:0031210///phosphatidylcholine binding+++GO:0031267///small GTPase binding+++GO:0034185///apolipoprotein binding+++GO:0034186///apolipoprotein A-I binding+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046623///sphingolipid-translocating ATPase activity+++GO:0051117///ATPase binding+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0090556///phosphatidylserine-translocating ATPase activity+++GO:0120020///intermembrane cholesterol transfer activity" "GO:0002790///peptide secretion+++GO:0006497///protein lipidation+++GO:0006869///lipid transport+++GO:0006911///phagocytosis, engulfment+++GO:0007040///lysosome organization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007584///response to nutrient+++GO:0008203///cholesterol metabolic process+++GO:0009306///protein secretion+++GO:0010875///positive regulation of cholesterol efflux+++GO:0015914///phospholipid transport+++GO:0016197///endosomal transport+++GO:0023061///signal release+++GO:0030301///cholesterol transport+++GO:0031667///response to nutrient levels+++GO:0032367///intracellular cholesterol transport+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034616///response to laminar fluid shear stress+++GO:0035690///cellular response to drug+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0045332///phospholipid translocation+++GO:0055085///transmembrane transport+++GO:0055091///phospholipid homeostasis+++GO:0060155///platelet dense granule organization+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071300///cellular response to retinoic acid+++GO:0071345///cellular response to cytokine stimulus+++GO:0071397///cellular response to cholesterol+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0071806///protein transmembrane transport+++GO:0090108///positive regulation of high-density lipoprotein particle assembly+++GO:0099039///sphingolipid translocation+++GO:0120009///intermembrane lipid transfer+++GO:0140115///export across plasma membrane" 11304 11304 'Abca4' mRNA 149 144 129 1.12 1.07 1.09 1.48 1.15 1.2 1.093333333 1.276666667 226 167 175 140.6666667 189.3333333 0.053333945 0.416129155 02010///ABC transporters GO:0001750///photoreceptor outer segment+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005319///lipid transporter activity+++GO:0005501///retinoid binding+++GO:0005502///11-cis retinal binding+++GO:0005503///all-trans retinal binding+++GO:0005524///ATP binding+++GO:0005548///phospholipid transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity" GO:0001523///retinoid metabolic process+++GO:0006649///phospholipid transfer to membrane+++GO:0006869///lipid transport+++GO:0007601///visual perception+++GO:0042574///retinal metabolic process+++GO:0045332///phospholipid translocation+++GO:0045494///photoreceptor cell maintenance+++GO:0050896///response to stimulus+++GO:0055085///transmembrane transport 11305 11305 'Abca2' mRNA 4003 4054 3754 25.58 25.65 25.66 15.33 14.05 14.31 25.63 14.56333333 2754 2454 2488 3937 2565.333333 7.17E-25 -0.629832934 02010///ABC transporters+++04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0061135///endopeptidase regulator activity+++GO:0099038///ceramide-translocating ATPase activity" GO:0001573///ganglioside metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006684///sphingomyelin metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0006869///lipid transport+++GO:0007626///locomotory behavior+++GO:0008203///cholesterol metabolic process+++GO:0010872///regulation of cholesterol esterification+++GO:0032289///central nervous system myelin formation+++GO:0032383///regulation of intracellular cholesterol transport+++GO:0032384///negative regulation of intracellular cholesterol transport+++GO:0032805///positive regulation of low-density lipoprotein particle receptor catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0042986///positive regulation of amyloid precursor protein biosynthetic process+++GO:0046512///sphingosine biosynthetic process+++GO:0048545///response to steroid hormone+++GO:0052548///regulation of endopeptidase activity+++GO:0055085///transmembrane transport+++GO:0060049///regulation of protein glycosylation+++GO:0070723///response to cholesterol+++GO:0071072///negative regulation of phospholipid biosynthetic process+++GO:0090155///negative regulation of sphingolipid biosynthetic process+++GO:0090156///cellular sphingolipid homeostasis+++GO:0090370///negative regulation of cholesterol efflux+++GO:0099040///ceramide translocation+++GO:1901873///regulation of post-translational protein modification+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:1904375///regulation of protein localization to cell periphery+++GO:1905598///negative regulation of low-density lipoprotein receptor activity+++GO:1905601///negative regulation of receptor-mediated endocytosis involved in cholesterol transport+++GO:2000008///regulation of protein localization to cell surface 11306 11306 'Abcb7' mRNA 434.19 442.22 414.92 4.01 4.01 4.06 3.01 3.01 3.07 4.026666667 3.03 376.02 367.01 371.1 430.4433333 371.3766667 0.103797422 -0.222849533 02010///ABC transporters GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity" GO:0006879///cellular iron ion homeostasis+++GO:0016226///iron-sulfur cluster assembly+++GO:0034755///iron ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070455///positive regulation of heme biosynthetic process+++GO:1903331///positive regulation of iron-sulfur cluster assembly+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process 11307 11307 'Abcg1' mRNA 2682 2564 2448 24.47 23 23.69 46.95 45.77 45.45 23.72 46.05666667 5924 5643 5555 2564.666667 5707.333333 3.69E-89 1.142566914 02010///ABC transporters+++05417///Lipid and atherosclerosis GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0034041///sterol-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046982///protein heterodimerization activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0120020///intermembrane cholesterol transfer activity" GO:0006869///lipid transport+++GO:0008203///cholesterol metabolic process+++GO:0010033///response to organic substance+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010872///regulation of cholesterol esterification+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010888///negative regulation of lipid storage+++GO:0030301///cholesterol transport+++GO:0032367///intracellular cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0033993///response to lipid+++GO:0034204///lipid translocation+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034436///glycoprotein transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042632///cholesterol homeostasis+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043691///reverse cholesterol transport+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0050714///positive regulation of protein secretion+++GO:0055085///transmembrane transport+++GO:0055091///phospholipid homeostasis+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0120009///intermembrane lipid transfer+++GO:1901998///toxin transport+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1904411///positive regulation of secretory granule organization 11308 11308 'Abi1' mRNA 1413.55 1482.88 1219.7 22.66 23.57 20.76 27.86 24.95 26.42 22.33 26.41 1936.86 1702 1778.54 1372.043333 1805.8 1.30E-06 0.387062547 05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0031209///SCAR complex+++GO:0031252///cell leading edge+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0035591///signaling adaptor activity GO:0001756///somitogenesis+++GO:0008154///actin polymerization or depolymerization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035855///megakaryocyte development+++GO:0048813///dendrite morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0072673///lamellipodium morphogenesis+++GO:0099527///postsynapse to nucleus signaling pathway 11350 11350 'Abl1' mRNA 1105 1208.94 1136.6 9.11 9.59 9.44 8.39 8.36 7.88 9.38 8.21 1188.92 1159.52 1108.97 1150.18 1152.47 0.935869834 -0.009506474 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04110///Cell cycle+++04360///Axon guidance+++04722///Neurotrophin signaling pathway+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05220///Chronic myeloid leukemia+++05416///Viral myocarditis GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000400///four-way junction DNA binding+++GO:0000405///bubble DNA binding+++GO:0001784///phosphotyrosine residue binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0030145///manganese ion binding+++GO:0038191///neuropilin binding+++GO:0042169///SH2 domain binding+++GO:0046872///metal ion binding+++GO:0046875///ephrin receptor binding+++GO:0051015///actin filament binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070064///proline-rich region binding+++GO:0070097///delta-catenin binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0001843///neural tube closure+++GO:0001922///B-1 B cell homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002322///B cell proliferation involved in immune response+++GO:0002333///transitional one stage B cell differentiation+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0006909///phagocytosis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0006979///response to oxidative stress+++GO:0007155///cell adhesion+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007229///integrin-mediated signaling pathway+++GO:0007611///learning or memory+++GO:0009791///post-embryonic development+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021587///cerebellum morphogenesis+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030035///microspike assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030182///neuron differentiation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030516///regulation of axon extension+++GO:0031113///regulation of microtubule polymerization+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0038189///neuropilin signaling pathway+++GO:0042100///B cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0042770///signal transduction in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045184///establishment of protein localization+++GO:0045580///regulation of T cell differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046632///alpha-beta T cell differentiation+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048668///collateral sprouting+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050798///activated T cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0050885///neuromuscular process controlling balance+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051726///regulation of cell cycle+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060020///Bergmann glial cell differentiation+++GO:0060563///neuroepithelial cell differentiation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071103///DNA conformation change+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0072359///circulatory system development+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090135///actin filament branching+++GO:1900006///positive regulation of dendrite development+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900275///negative regulation of phospholipase C activity+++GO:1901216///positive regulation of neuron death+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:1903053///regulation of extracellular matrix organization+++GO:1903055///positive regulation of extracellular matrix organization+++GO:1903210///glomerular visceral epithelial cell apoptotic process+++GO:1904528///positive regulation of microtubule binding+++GO:1904531///positive regulation of actin filament binding+++GO:1905244///regulation of modification of synaptic structure+++GO:1905555///positive regulation blood vessel branching+++GO:1990051///activation of protein kinase C activity+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000772///regulation of cellular senescence+++GO:2000773///negative regulation of cellular senescence+++GO:2001020///regulation of response to DNA damage stimulus" 11352 11352 'Abl2' mRNA 419.1 363 303.03 2.08 1.77 1.61 1.97 1.51 1.78 1.82 1.753333333 466.26 345 403.01 361.71 404.7566667 0.399941643 0.152143626 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++05208///Chemical carcinogenesis - reactive oxygen species+++05416///Viral myocarditis GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0031410///cytoplasmic vesicle+++GO:0043197///dendritic spine+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding "GO:0001843///neural tube closure+++GO:0002118///aggressive behavior+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007612///learning+++GO:0007628///adult walking behavior+++GO:0008542///visual learning+++GO:0009791///post-embryonic development+++GO:0010863///positive regulation of phospholipase C activity+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0016322///neuron remodeling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021587///cerebellum morphogenesis+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0022414///reproductive process+++GO:0030036///actin cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0031223///auditory behavior+++GO:0032092///positive regulation of protein binding+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0034613///cellular protein localization+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035264///multicellular organism growth+++GO:0035640///exploration behavior+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046632///alpha-beta T cell differentiation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048813///dendrite morphogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0051017///actin filament bundle assembly+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0060020///Bergmann glial cell differentiation+++GO:0060074///synapse maturation+++GO:0060563///neuroepithelial cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0072359///circulatory system development+++GO:0097062///dendritic spine maintenance+++GO:1903053///regulation of extracellular matrix organization+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process" 113523645 113523645 'Lrrc70' mRNA 238 236 225 12.07 11.82 12.11 7.56 8.47 8.18 12 8.07 171 187 179 233 179 0.032835419 -0.390927085 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 11363 11363 'Acadl' mRNA 1230 1399 1261 36.05 40.4 39.21 50.51 53.47 49.79 38.55333333 51.25666667 1981 2047 1890 1296.666667 1972.666667 1.30E-13 0.594484395 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0031966///mitochondrial membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004466///long-chain-acyl-CoA dehydrogenase activity+++GO:0016401///palmitoyl-CoA oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding" "GO:0001659///temperature homeostasis+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0009409///response to cold+++GO:0019254///carnitine metabolic process, CoA-linked+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0042413///carnitine catabolic process+++GO:0042758///long-chain fatty acid catabolic process+++GO:0044242///cellular lipid catabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0090181///regulation of cholesterol metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis" 11364 11364 'Acadm' mRNA 1636 1709 1685 45.02 46.33 49.19 43.06 49.75 44.36 46.84666667 45.72333333 1799 2029 1794 1676.666667 1874 0.114756025 0.149005473 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04936///Alcoholic liver disease" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0030424///axon+++GO:0031966///mitochondrial membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0070991///medium-chain-acyl-CoA dehydrogenase activity" "GO:0001889///liver development+++GO:0005978///glycogen biosynthetic process+++GO:0006082///organic acid metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0007507///heart development+++GO:0009409///response to cold+++GO:0009437///carnitine metabolic process+++GO:0009791///post-embryonic development+++GO:0019254///carnitine metabolic process, CoA-linked+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0042594///response to starvation+++GO:0045329///carnitine biosynthetic process+++GO:0051791///medium-chain fatty acid metabolic process+++GO:0051793///medium-chain fatty acid catabolic process+++GO:0055007///cardiac muscle cell differentiation" 11370 11370 'Acadvl' mRNA 2740 2694 2705 70.63 68.4 73.97 75.21 75.27 74.67 71 75.05 3355 3278 3224 2713 3285.666667 6.80E-05 0.263640119 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++04936///Alcoholic liver disease GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0042645///mitochondrial nucleoid "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004466///long-chain-acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0001659///temperature homeostasis+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009062///fatty acid catabolic process+++GO:0009409///response to cold+++GO:0030855///epithelial cell differentiation+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0090181///regulation of cholesterol metabolic process 113853 113853 'Vmn1r53' mRNA 0 1 0 0 0.05 0 0 0 0.25 0.016666667 0.083333333 0 0 5 0.333333333 1.666666667 0.550044142 2.212906204 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity+++GO:0038023///signaling receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007606///sensory perception of chemical stimulus+++GO:0019236///response to pheromone 113868 113868 'Acaa1a' mRNA 2282.17 2482.46 2281.98 76.16 81.54 80.81 87.2 86.16 89.38 79.50333333 87.58 3001.56 2891.58 2980.9 2348.87 2958.013333 1.05E-06 0.321216806 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00592///alpha-Linolenic acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome" GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0008775///acetate CoA-transferase activity+++GO:0016401///palmitoyl-CoA oxidase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0050633///acetyl-CoA C-myristoyltransferase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0008206///bile acid metabolic process+++GO:0010124///phenylacetate catabolic process 113939900 113939900 'Gm51263' mRNA 1 2 1 0.07 0.13 0.07 0.17 0.06 0.12 0.09 0.116666667 3 1 2 1.333333333 2 0.822791725 0.573859724 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway 11409 11409 'Acads' mRNA 562 617 454 17.24 18.65 14.78 19.62 19.47 19.77 16.89 19.62 735 712 717 544.3333333 721.3333333 5.98E-04 0.39926331 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++00650///Butanoate metabolism+++01200///Carbon metabolism+++01212///Fatty acid metabolism" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005813///centrosome+++GO:0031966///mitochondrial membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004085///butyryl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0046359///butyrate catabolic process 114128 114128 'Laptm4b' mRNA 4095 4346 4103 123.64 129.3 131.42 93.82 94.74 96.78 128.12 95.11333333 3572 3521 3566 4181.333333 3553 5.83E-05 -0.246664248 04142///Lysosome "GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0032585///multivesicular body membrane+++GO:0042995///cell projection+++GO:0097487///multivesicular body, internal vesicle" GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0097001///ceramide binding+++GO:1902936///phosphatidylinositol bisphosphate binding GO:0007032///endosome organization+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0097213///regulation of lysosomal membrane permeability+++GO:1905166///negative regulation of lysosomal protein catabolic process+++GO:1905671///regulation of lysosome organization 114142 114142 'Foxp2' mRNA 45 76 45 0.36 0.6 0.4 0.64 0.47 0.45 0.453333333 0.52 92 66 62 55.33333333 73.33333333 0.304183864 0.398047699 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0010467///gene expression+++GO:0021549///cerebellum development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021757///caudate nucleus development+++GO:0021758///putamen development+++GO:0021987///cerebral cortex development+++GO:0030324///lung development+++GO:0030900///forebrain development+++GO:0033574///response to testosterone+++GO:0040007///growth+++GO:0042297///vocal learning+++GO:0043010///camera-type eye development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048286///lung alveolus development+++GO:0048745///smooth muscle tissue development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060013///righting reflex+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0071625///vocalization behavior+++GO:0098582///innate vocalization behavior" 114143 114143 'Atp6v0b' mRNA 3457 3425 3372 220.02 216.32 228.71 311.84 317.07 321.08 221.6833333 316.6633333 5598 5537 5561 3418 5565.333333 1.43E-33 0.69123184 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0005768///endosome+++GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033177///proton-transporting two-sector ATPase complex, proton-transporting domain+++GO:0033179///proton-transporting V-type ATPase, V0 domain" "GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 11416 11416 'Slc33a1' mRNA 884.06 831.98 812.68 15.52 14.4 15.13 17.3 16.53 16.5 15.01666667 16.77666667 1131.02 1058.43 1043.46 842.9066667 1077.636667 1.76E-04 0.343049354 00604///Glycosphingolipid biosynthesis - ganglio series GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008521///acetyl-CoA transmembrane transporter activity+++GO:0015295///solute:proton symporter activity GO:0015876///acetyl-CoA transport+++GO:0030509///BMP signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:1902600///proton transmembrane transport 11418 11418 'Asic2' mRNA 26 20 15 0.4 0.37 0.27 0.77 0.75 0.68 0.346666667 0.733333333 42 41 36 20.33333333 39.66666667 0.046781811 0.957967604 04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0005216///ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0015280///ligand-gated sodium channel activity+++GO:0022839///ion gated channel activity GO:0003026///regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0007602///phototransduction+++GO:0007605///sensory perception of sound+++GO:0009612///response to mechanical stimulus+++GO:0010447///response to acidic pH+++GO:0019229///regulation of vasoconstriction+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035418///protein localization to synapse+++GO:0035690///cellular response to drug+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043066///negative regulation of apoptotic process+++GO:0050915///sensory perception of sour taste+++GO:0050974///detection of mechanical stimulus involved in sensory perception+++GO:0051965///positive regulation of synapse assembly+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071468///cellular response to acidic pH+++GO:2001259///positive regulation of cation channel activity 11419 11419 'Asic1' mRNA 1287 1201 1191 18.26 16.73 17.91 1.51 2.61 1.8 17.63333333 1.973333333 122 206 141 1226.333333 156.3333333 6.26E-91 -2.980156964 04750///Inflammatory mediator regulation of TRP channels GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045202///synapse GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0015280///ligand-gated sodium channel activity+++GO:0022839///ion gated channel activity+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0044736///acid-sensing ion channel activity GO:0001662///behavioral fear response+++GO:0001975///response to amphetamine+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0010447///response to acidic pH+++GO:0034220///ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0046929///negative regulation of neurotransmitter secretion+++GO:0050915///sensory perception of sour taste+++GO:0070207///protein homotrimerization+++GO:0070588///calcium ion transmembrane transport+++GO:0071467///cellular response to pH+++GO:0098662///inorganic cation transmembrane transport 11421 11421 'Ace' mRNA 47 47 25 0.57 0.5 0.29 1.09 1.12 0.68 0.453333333 0.963333333 102 102 69 39.66666667 91 5.66E-04 1.195617854 04614///Renin-angiotensin system+++04924///Renin secretion+++05142///Chagas disease+++05171///Coronavirus disease - COVID-19+++05410///Hypertrophic cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0031982///vesicle+++GO:0070062///extracellular exosome+++GO:0097225///sperm midpiece GO:0003779///actin binding+++GO:0004175///endopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008238///exopeptidase activity+++GO:0008240///tripeptidyl-peptidase activity+++GO:0008241///peptidyl-dipeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0031404///chloride ion binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031711///bradykinin receptor binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070573///metallodipeptidase activity+++GO:1901363///heterocyclic compound binding GO:0001822///kidney development+++GO:0002446///neutrophil mediated immunity+++GO:0003081///regulation of systemic arterial blood pressure by renin-angiotensin+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0007283///spermatogenesis+++GO:0008217///regulation of blood pressure+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010815///bradykinin catabolic process+++GO:0014910///regulation of smooth muscle cell migration+++GO:0019233///sensory perception of pain+++GO:0031100///animal organ regeneration+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032496///response to lipopolysaccharide+++GO:0035814///negative regulation of renal sodium excretion+++GO:0042310///vasoconstriction+++GO:0042447///hormone catabolic process+++GO:0042755///eating behavior+++GO:0043065///positive regulation of apoptotic process+++GO:0043171///peptide catabolic process+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0046325///negative regulation of glucose import+++GO:0048286///lung alveolus development+++GO:0050435///amyloid-beta metabolic process+++GO:0050482///arachidonic acid secretion+++GO:0050729///positive regulation of inflammatory response+++GO:0050769///positive regulation of neurogenesis+++GO:0060047///heart contraction+++GO:0060177///regulation of angiotensin metabolic process+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0071838///cell proliferation in bone marrow+++GO:0090281///negative regulation of calcium ion import+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:1902033///regulation of hematopoietic stem cell proliferation+++GO:1903597///negative regulation of gap junction assembly+++GO:2000170///positive regulation of peptidyl-cysteine S-nitrosylation 114229 114229 'Kiss1r' mRNA 257 255 243 4.49 4.38 4.48 3.65 3.27 3.41 4.45 3.443333333 242 211 220 251.6666667 224.3333333 0.343296511 -0.178164937 04080///Neuroactive ligand-receptor interaction+++04929///GnRH secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008188///neuropeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0042923///neuropeptide binding GO:0000186///activation of MAPKK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0019722///calcium-mediated signaling+++GO:0030336///negative regulation of cell migration+++GO:0043410///positive regulation of MAPK cascade+++GO:0046887///positive regulation of hormone secretion+++GO:0050482///arachidonic acid secretion+++GO:0050806///positive regulation of synaptic transmission+++GO:0051496///positive regulation of stress fiber assembly 11423 11423 'Ache' mRNA 218 232 200 4.24 4.69 4.15 1.14 0.93 1.66 4.36 1.243333333 61 50 85 216.6666667 65.33333333 6.28E-14 -1.739573546 00564///Glycerophospholipid metabolism+++04725///Cholinergic synapse GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031225///anchored component of membrane+++GO:0031594///neuromuscular junction+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003990///acetylcholinesterase activity+++GO:0004104///cholinesterase activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0016787///hydrolase activity+++GO:0017171///serine hydrolase activity+++GO:0033265///choline binding+++GO:0042166///acetylcholine binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043236///laminin binding+++GO:0043621///protein self-association+++GO:0052689///carboxylic ester hydrolase activity GO:0001919///regulation of receptor recycling+++GO:0002076///osteoblast development+++GO:0006581///acetylcholine catabolic process+++GO:0007155///cell adhesion+++GO:0007416///synapse assembly+++GO:0008291///acetylcholine metabolic process+++GO:0019695///choline metabolic process+++GO:0031623///receptor internalization+++GO:0042135///neurotransmitter catabolic process+++GO:0050772///positive regulation of axonogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0070997///neuron death+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis 114230 114230 'Aipl1' mRNA 3 5 0 0.11 0.18 0 0.03 0.07 0.07 0.096666667 0.056666667 3 3 6 2.666666667 4 0.75009672 0.605798771 04934///Cushing syndrome+++05207///Chemical carcinogenesis - receptor activation GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001918///farnesylated protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity "GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001895///retina homeostasis+++GO:0007601///visual perception+++GO:0007603///phototransduction, visible light+++GO:0018343///protein farnesylation+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process" 114249 114249 'Npnt' mRNA 894 943 899 10.57 11.1 11.56 11.1 9.99 10.77 11.07666667 10.62 1063 935 1005 912 1001 0.244678632 0.121597273 04512///ECM-receptor interaction GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016020///membrane+++GO:0030485///smooth muscle contractile fiber+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0045184///establishment of protein localization+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071356///cellular response to tumor necrosis factor+++GO:0097195///pilomotor reflex+++GO:2000721///positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 11425 11425 'Apoc4' mRNA 3 1 3 0.48 0.16 0.51 2.67 4.91 3.48 0.383333333 3.686666667 19 33.86 23.81 2.333333333 25.55666667 5.98E-05 3.409702944 GO:0005576///extracellular region+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle GO:0006869///lipid transport+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0070328///triglyceride homeostasis 114255 114255 'Dok4' mRNA 253.78 211.93 206.15 4.57 3.91 3.67 4.97 4.34 4.97 4.05 4.76 298.85 267.52 311.67 223.9533333 292.68 0.029249832 0.375774557 GO:0005737///cytoplasm GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0043410///positive regulation of MAPK cascade 11426 11426 'Macf1' mRNA 3399.56 3256.15 2964.72 9.57 9.03 8.96 7.53 7.26 7.51 9.186666667 7.433333333 3132.6 2943.82 3061.83 3206.81 3046.083333 0.232452409 -0.084743806 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008092///cytoskeletal protein binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0051011///microtubule minus-end binding+++GO:0051015///actin filament binding GO:0001707///mesoderm formation+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0006928///movement of cell or subcellular component+++GO:0007163///establishment or maintenance of cell polarity+++GO:0008104///protein localization+++GO:0010632///regulation of epithelial cell migration+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030334///regulation of cell migration+++GO:0032886///regulation of microtubule-based process+++GO:0042060///wound healing+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045773///positive regulation of axon extension+++GO:0051893///regulation of focal adhesion assembly+++GO:0150011///regulation of neuron projection arborization 11428 11428 'Aco1' mRNA 628 737 664.84 9.25 10.63 10.63 16.17 16.37 14.45 10.17 15.66333333 1253 1224 1077 676.6133333 1184.666667 2.22E-15 0.796949321 00020///Citrate cycle (TCA cycle)+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0003723///RNA binding+++GO:0003994///aconitate hydratase activity+++GO:0016829///lyase activity+++GO:0030350///iron-responsive element binding+++GO:0046872///metal ion binding+++GO:0047780///citrate dehydratase activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051538///3 iron, 4 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006417///regulation of translation+++GO:0006879///cellular iron ion homeostasis+++GO:0009791///post-embryonic development+++GO:0010040///response to iron(II) ion+++GO:0010468///regulation of gene expression+++GO:0050892///intestinal absorption 11429 11429 'Aco2' mRNA 7073.83 7626 7485 141.21 149.84 158.5 117.2 118.57 116.11 149.85 117.2933333 6754 6673 6479 7394.943333 6635.333333 0.009308654 -0.169328824 00020///Citrate cycle (TCA cycle)+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043209///myelin sheath "GO:0003994///aconitate hydratase activity+++GO:0005506///iron ion binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0047780///citrate dehydratase activity+++GO:0051536///iron-sulfur cluster binding+++GO:0051538///3 iron, 4 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0001889///liver development+++GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006102///isocitrate metabolic process+++GO:0035900///response to isolation stress 11430 11430 'Acox1' mRNA 2022 1997 2092.78 27.73 27.05 30.97 25.89 25.74 24.71 28.58333333 25.44666667 2163 2117.32 1994 2037.26 2091.44 0.830833224 0.024162323 00071///Fatty acid degradation+++00410///beta-Alanine metabolism+++00592///alpha-Linolenic acid metabolism+++00640///Propanoate metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04024///cAMP signaling pathway+++04146///Peroxisome+++04936///Alcoholic liver disease GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol "GO:0003997///acyl-CoA oxidase activity+++GO:0005504///fatty acid binding+++GO:0016401///palmitoyl-CoA oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0030165///PDZ domain binding+++GO:0042803///protein homodimerization activity+++GO:0046592///polyamine oxidase activity+++GO:0047485///protein N-terminus binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0052899///N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity+++GO:0052901///spermine:oxygen oxidoreductase (spermidine-forming) activity+++GO:0052902///spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity+++GO:0052903///N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity+++GO:0052904///N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity+++GO:0071949///FAD binding" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0006598///polyamine catabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006693///prostaglandin metabolic process+++GO:0007283///spermatogenesis+++GO:0008215///spermine metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0009446///putrescine biosynthetic process+++GO:0009447///putrescine catabolic process+++GO:0016559///peroxisome fission+++GO:0019395///fatty acid oxidation+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0042632///cholesterol homeostasis+++GO:0046203///spermidine catabolic process+++GO:0046208///spermine catabolic process+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0055088///lipid homeostasis+++GO:1901307///positive regulation of spermidine biosynthetic process 114301 114301 'Palmd' mRNA 252 252 296 5.89 5.8 7.35 17.53 18.46 16.22 6.346666667 17.40333333 861 885 771 266.6666667 839 1.96E-37 1.638408252 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0005515///protein binding GO:0008360///regulation of cell shape 114304 114304 'Slc28a3' mRNA 51.45 30.59 55.24 0.6 0.35 0.69 0.23 0.17 0.21 0.546666667 0.203333333 22.45 16.14 19.77 45.76 19.45333333 0.007970293 -1.277675578 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0005337///nucleoside transmembrane transporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0015213///uridine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015389///pyrimidine- and adenine-specific:sodium symporter activity+++GO:0015390///purine-specific nucleoside:sodium symporter activity GO:0001895///retina homeostasis+++GO:0015855///pyrimidine nucleobase transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0015862///uridine transport+++GO:0015864///pyrimidine nucleoside transport+++GO:0035725///sodium ion transmembrane transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1901642///nucleoside transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport 11431 11431 'Acp1' mRNA 1463 1519 1470.99 25.8 26.36 27.52 29.41 28.81 29.13 26.56 29.11666667 1918.99 1836 1840 1484.33 1864.996667 2.24E-05 0.317103161 00730///Thiamine metabolism+++00740///Riboflavin metabolism+++04520///Adherens junction+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0042383///sarcolemma+++GO:0043005///neuron projection GO:0003993///acid phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding GO:0006470///protein dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 11432 11432 'Acp2' mRNA 1894.02 1998.75 1921.5 21.86 22.64 23.47 25.15 24.97 23.57 22.65666667 24.56333333 2513.71 2438.48 2266.21 1938.09 2406.133333 5.22E-05 0.299706464 00740///Riboflavin metabolism+++04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043202///lysosomal lumen GO:0001784///phosphotyrosine residue binding+++GO:0003993///acid phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0001501///skeletal system development+++GO:0006470///protein dephosphorylation+++GO:0007040///lysosome organization+++GO:0010033///response to organic substance+++GO:0016311///dephosphorylation+++GO:0048102///autophagic cell death 11433 11433 'Acp5' mRNA 61 55 62 2.54 2.28 2.79 49.97 46.64 45.47 2.536666667 47.36 1326 1220 1175 59.33333333 1240.333333 1.48E-196 4.373139865 00740///Riboflavin metabolism+++04142///Lysosome+++04380///Osteoclast differentiation+++05323///Rheumatoid arthritis GO:0005615///extracellular space+++GO:0005764///lysosome GO:0003993///acid phosphatase activity+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0007162///negative regulation of cell adhesion+++GO:0016311///dephosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032929///negative regulation of superoxide anion generation+++GO:0034097///response to cytokine+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045453///bone resorption+++GO:0050728///negative regulation of inflammatory response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060349///bone morphogenesis 114332 114332 'Lyve1' mRNA 63 68 64 1.34 1.43 1.45 24.03 23.05 24.65 1.406666667 23.91 1298 1216 1289 65 1267.666667 1.44E-205 4.274268925 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery GO:0004888///transmembrane signaling receptor activity+++GO:0005540///hyaluronic acid binding GO:0006027///glycosaminoglycan catabolic process+++GO:0007155///cell adhesion 11434 11434 'Acr' mRNA 1.13 4.02 2 0.01 0.04 0.05 0.04 0.02 0.16 0.033333333 0.073333333 3.95 2.08 7 2.383333333 4.343333333 0.670106748 0.772907965 GO:0001669///acrosomal vesicle+++GO:0005798///Golgi-associated vesicle+++GO:0032991///protein-containing complex+++GO:0043159///acrosomal matrix GO:0004040///amidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0005537///mannose binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042806///fucose binding GO:0002077///acrosome matrix dispersal+++GO:0006508///proteolysis+++GO:0007190///activation of adenylate cyclase activity+++GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0007340///acrosome reaction+++GO:0007341///penetration of zona pellucida+++GO:0030163///protein catabolic process+++GO:0048545///response to steroid hormone 11435 11435 'Chrna1' mRNA 604.48 648.71 638.71 7.52 7.94 8.43 1.34 1.62 1.42 7.963333333 1.46 123.51 146.14 127.34 630.6333333 132.33 5.53E-56 -2.266673619 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007274///neuromuscular synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0046716///muscle cell cellular homeostasis+++GO:0048630///skeletal muscle tissue growth+++GO:0050877///nervous system process+++GO:0050881///musculoskeletal movement+++GO:0050905///neuromuscular process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0070050///neuron cellular homeostasis" 11438 11438 'Chrna4' mRNA 253 238 213 3.02 2.8 2.71 0.84 1.07 1.28 2.843333333 1.063333333 81 103 119 234.6666667 101 3.93E-09 -1.223733123 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05033///Nicotine addiction+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse+++GO:0098981///cholinergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0044877///protein-containing complex binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001508///action potential+++GO:0001666///response to hypoxia+++GO:0006281///DNA repair+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007585///respiratory gaseous exchange+++GO:0007626///locomotory behavior+++GO:0014059///regulation of dopamine secretion+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035095///behavioral response to nicotine+++GO:0035640///exploration behavior+++GO:0042113///B cell activation+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0050890///cognition+++GO:0051899///membrane depolarization+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1903048///regulation of acetylcholine-gated cation channel activity+++GO:2000300///regulation of synaptic vesicle exocytosis" 11440 11440 'Chrna6' mRNA 0 2 3 0 0.04 0.06 0 0 0 0.033333333 0 0 0 0 1.666666667 0 0.365073976 -3.217286235 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1901363///heterocyclic compound binding GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0014059///regulation of dopamine secretion+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051899///membrane depolarization+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:2000300///regulation of synaptic vesicle exocytosis 11441 11441 'Chrna7' mRNA 3 13 15 0.08 0.35 0.43 0.19 0.05 0.15 0.286666667 0.13 8 2 6 10.33333333 5.333333333 0.383491881 -0.986739108 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05033///Nicotine addiction+++05207///Chemical carcinogenesis - receptor activation GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0009897///external side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030673///axolemma+++GO:0032279///asymmetric synapse+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098690///glycinergic synapse+++GO:0098793///presynapse+++GO:0098981///cholinergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099065///integral component of spine apparatus membrane GO:0001540///amyloid-beta binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0015464///acetylcholine receptor activity+++GO:0015643///toxic substance binding+++GO:0017081///chloride channel regulator activity+++GO:0019901///protein kinase binding+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0042803///protein homodimerization activity+++GO:0051117///ATPase binding+++GO:0097110///scaffold protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001988///positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0009409///response to cold+++GO:0014061///regulation of norepinephrine secretion+++GO:0019228///neuronal action potential+++GO:0030317///flagellated sperm motility+++GO:0032094///response to food+++GO:0032222///regulation of synaptic transmission, cholinergic+++GO:0032225///regulation of synaptic transmission, dopaminergic+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035095///behavioral response to nicotine+++GO:0042110///T cell activation+++GO:0042113///B cell activation+++GO:0042391///regulation of membrane potential+++GO:0042698///ovulation cycle+++GO:0045471///response to ethanol+++GO:0048149///behavioral response to ethanol+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0050877///nervous system process+++GO:0050893///sensory processing+++GO:0051247///positive regulation of protein metabolic process+++GO:0051823///regulation of synapse structural plasticity+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060112///generation of ovulation cycle rhythm+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0097061///dendritic spine organization+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0140059///dendrite arborization+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901214///regulation of neuron death+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1904645///response to amyloid-beta+++GO:1905144///response to acetylcholine+++GO:1905906///regulation of amyloid fibril formation+++GO:1905920///positive regulation of CoA-transferase activity+++GO:1905923///positive regulation of acetylcholine biosynthetic process+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2001023///regulation of response to drug" 11443 11443 'Chrnb1' mRNA 1010 1132 1056 26.69 29.34 29.67 31.4 30.03 31.55 28.56666667 30.99333333 1372 1276 1334 1066 1327.333333 5.38E-04 0.304048683 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015267///channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001941///postsynaptic membrane organization+++GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007274///neuromuscular synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0035095///behavioral response to nicotine+++GO:0042391///regulation of membrane potential+++GO:0048747///muscle fiber development+++GO:0050877///nervous system process+++GO:0055001///muscle cell development+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential" 11444 11444 'Chrnb2' mRNA 410 394 265 4.06 3.83 2.78 0.4 0.32 0.49 3.556666667 0.403333333 46 36 56 356.3333333 46 1.87E-39 -2.957655887 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++05033///Nicotine addiction+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098691///dopaminergic synapse+++GO:0098981///cholinergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:0044877///protein-containing complex binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001508///action potential+++GO:0001661///conditioned taste aversion+++GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0007612///learning+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0008542///visual learning+++GO:0014059///regulation of dopamine secretion+++GO:0019233///sensory perception of pain+++GO:0021562///vestibulocochlear nerve development+++GO:0021631///optic nerve morphogenesis+++GO:0021771///lateral geniculate nucleus development+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030890///positive regulation of B cell proliferation+++GO:0032225///regulation of synaptic transmission, dopaminergic+++GO:0032226///positive regulation of synaptic transmission, dopaminergic+++GO:0033603///positive regulation of dopamine secretion+++GO:0034220///ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035095///behavioral response to nicotine+++GO:0035176///social behavior+++GO:0042053///regulation of dopamine metabolic process+++GO:0042113///B cell activation+++GO:0042220///response to cocaine+++GO:0042320///regulation of circadian sleep/wake cycle, REM sleep+++GO:0042391///regulation of membrane potential+++GO:0045188///regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0045471///response to ethanol+++GO:0045759///negative regulation of action potential+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050877///nervous system process+++GO:0050890///cognition+++GO:0051899///membrane depolarization+++GO:0051963///regulation of synapse assembly+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060084///synaptic transmission involved in micturition+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1905144///response to acetylcholine+++GO:2000300///regulation of synaptic vesicle exocytosis" 11447 11447 'Chrnd' mRNA 0 2 0 0 0.04 0 0.1 0.03 0.08 0.013333333 0.07 6 2 5 0.666666667 4.333333333 0.185337275 2.705302016 04080///Neuroactive ligand-receptor interaction GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042166///acetylcholine binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0048630///skeletal muscle tissue growth+++GO:0050877///nervous system process+++GO:0050881///musculoskeletal movement+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential 114479 114479 'Slc5a5' mRNA 121 145 113 2.28 2.68 2.25 14.15 14.55 14.44 2.403333333 14.38 865 869 855 126.3333333 863 5.81E-100 2.763013008 04918///Thyroid hormone synthesis GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008507///sodium:iodide symporter activity+++GO:0015111///iodide transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006590///thyroid hormone generation+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0015705///iodide transport+++GO:0055085///transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071371///cellular response to gonadotropin stimulus+++GO:1904200///iodide transmembrane transport 11448 11448 'Chrne' mRNA 27 19 24 1.06 0.69 0.96 0.22 0.27 0.46 0.903333333 0.316666667 6 8 13 23.33333333 9 0.039155906 -1.386275766 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential 11449 11449 'Chrng' mRNA 3 8 4 0.09 0.24 0.13 0.08 0.06 0.03 0.153333333 0.056666667 3 2 1 5 2 0.395391975 -1.329207032 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential 11450 11450 'Adipoq' mRNA 1 2 0 0.05 0.1 0 0.09 0.22 0.04 0.05 0.116666667 2 5 1 1 2.666666667 0.537922761 1.437835608 03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0033691///sialic acid binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006006///glucose metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0007165///signal transduction+++GO:0007584///response to nutrient+++GO:0007623///circadian rhythm+++GO:0009617///response to bacterium+++GO:0009744///response to sucrose+++GO:0009749///response to glucose+++GO:0009967///positive regulation of signal transduction+++GO:0010467///gene expression+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010906///regulation of glucose metabolic process+++GO:0014823///response to activity+++GO:0019395///fatty acid oxidation+++GO:0030336///negative regulation of cell migration+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0031667///response to nutrient levels+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032869///cellular response to insulin stimulus+++GO:0033034///positive regulation of myeloid cell apoptotic process+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0034383///low-density lipoprotein particle clearance+++GO:0034612///response to tumor necrosis factor+++GO:0035690///cellular response to drug+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045471///response to ethanol+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045650///negative regulation of macrophage differentiation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045923///positive regulation of fatty acid metabolic process+++GO:0046326///positive regulation of glucose import+++GO:0046888///negative regulation of hormone secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050765///negative regulation of phagocytosis+++GO:0050805///negative regulation of synaptic transmission+++GO:0050873///brown fat cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070543///response to linoleic acid+++GO:0070994///detection of oxidative stress+++GO:0071320///cellular response to cAMP+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071872///cellular response to epinephrine stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0090317///negative regulation of intracellular protein transport+++GO:0110113///positive regulation of lipid transporter activity+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900121///negative regulation of receptor binding+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:1905598///negative regulation of low-density lipoprotein receptor activity+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:2000478///positive regulation of metanephric glomerular visceral epithelial cell development+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity+++GO:2000534///positive regulation of renal albumin absorption+++GO:2000584///negative regulation of platelet-derived growth factor receptor-alpha signaling pathway+++GO:2000590///negative regulation of metanephric mesenchymal cell migration" 114564 114564 'Csprs' mRNA 20.9 27.16 17.63 0.42 0.54 0.38 1.38 1.11 1.83 0.446666667 1.44 78.38 61.81 100.62 21.89666667 80.27 8.00E-07 1.893614353 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004930///G protein-coupled receptor activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007186///G protein-coupled receptor signaling pathway 114565 114565 'Zbtb21' mRNA 634.13 602.21 624.61 5.36 5.13 5.93 4.22 3.9 4.36 5.473333333 4.16 550.02 478.06 537.27 620.3166667 521.7833333 0.030337458 -0.262856681 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding+++GO:0031208///POZ domain binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 114570 114570 'Crip3' mRNA 1362.93 1358.67 1219.47 55.02 56.68 55.63 6.94 7.35 6.45 55.77666667 6.913333333 351.79 331.21 329.09 1313.69 337.3633333 2.26E-95 -1.972498981 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0042098///T cell proliferation 114584 114584 'Clic1' mRNA 2299 2508 2316 122.68 132.21 131.13 441.53 436.95 424.12 128.6733333 434.2 9494 9162 8817 2374.333333 9157.666667 1.77E-248 1.935757056 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0034707///chloride channel complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity GO:0006749///glutathione metabolic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0051726///regulation of cell cycle+++GO:0051881///regulation of mitochondrial membrane potential 114585 114585 'D17H6S53E' mRNA 457.09 348.28 414.8 12.16 9.13 11.71 13.62 12.63 13.56 11 13.27 588.72 533.05 567.02 406.7233333 562.93 0.001043531 0.455111297 GO:0003674///molecular_function GO:0008150///biological_process 11459 11459 'Acta1' mRNA 8 4 6 0.32 0.16 0.25 0.17 0.32 0.29 0.243333333 0.26 5 9 8 6 7.333333333 0.83530643 0.280113407 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0005869///dynactin complex+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0030017///sarcomere+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0032991///protein-containing complex+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0009612///response to mechanical stimulus+++GO:0009991///response to extracellular stimulus+++GO:0010226///response to lithium ion+++GO:0010628///positive regulation of gene expression+++GO:0030240///skeletal muscle thin filament assembly+++GO:0043503///skeletal muscle fiber adaptation+++GO:0048545///response to steroid hormone+++GO:0048741///skeletal muscle fiber development+++GO:0071417///cellular response to organonitrogen compound+++GO:0090131///mesenchyme migration 114601 114601 'Ehbp1l1' mRNA 223.44 234.99 163.57 3.09 3.22 2.44 12.08 12.68 13.01 2.916666667 12.59 994.29 1008.25 1015.51 207.3333333 1006.016667 1.18E-78 2.27644904 GO:0005575///cellular_component+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0031941///filamentous actin+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030036///actin cytoskeleton organization 114602 114602 'Zmynd10' mRNA 841 841 759 25.2 25.14 24.07 2.69 2.35 2.69 24.80333333 2.576666667 108 84 99 813.6666667 97 7.83E-109 -3.079698825 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0034451///centriolar satellite GO:0005515///protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0046872///metal ion binding+++GO:0060090///molecular adaptor activity GO:0003341///cilium movement+++GO:0006457///protein folding+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0044458///motile cilium assembly+++GO:0061512///protein localization to cilium+++GO:0097722///sperm motility+++GO:1905505///positive regulation of motile cilium assembly 114604 114604 'Prdm15' mRNA 175 215 180 1.47 1.73 1.62 1.45 1.37 1.67 1.606666667 1.496666667 196 181 220 190 199 0.833092101 0.056473296 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0032259///methylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000035///regulation of stem cell division 114606 114606 'Tle6' mRNA 123 140 136 3.81 4.34 4.58 6.08 6.08 6.35 4.243333333 6.17 223 216 227 133 222 1.33E-04 0.726568703 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway+++04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0032991///protein-containing complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0070491///repressing transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007015///actin filament organization+++GO:0007284///spermatogonial cell division+++GO:0040019///positive regulation of embryonic development+++GO:0045666///positive regulation of neuron differentiation+++GO:0050769///positive regulation of neurogenesis+++GO:0051293///establishment of spindle localization+++GO:0051302///regulation of cell division+++GO:0051643///endoplasmic reticulum localization+++GO:0051646///mitochondrion localization+++GO:0060136///embryonic process involved in female pregnancy+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 11461 11461 'Actb' mRNA 86700.59 80158.77 82103.26 2582.75 2352.81 2594.63 6004.19 5771.17 6017.11 2510.063333 5930.823333 231697.68 217399.15 224726.27 82987.54 224607.7 1.84E-164 1.423278277 04015///Rap1 signaling pathway+++04145///Phagosome+++04210///Apoptosis+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04745///Phototransduction - fly+++04810///Regulation of actin cytoskeleton+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion+++05014///Amyotrophic lateral sclerosis+++05100///Bacterial invasion of epithelial cells+++05110///Vibrio cholerae infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05164///Influenza A+++05205///Proteoglycans in cancer+++05225///Hepatocellular carcinoma+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis+++05418///Fluid shear stress and atherosclerosis GO:0001725///stress fiber+++GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030863///cortical cytoskeleton+++GO:0032991///protein-containing complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043209///myelin sheath+++GO:0043296///apical junction complex+++GO:0044305///calyx of Held+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0070160///tight junction+++GO:0097433///dense body+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0030957///Tat protein binding+++GO:0042802///identical protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0098973///structural constituent of postsynaptic actin cytoskeleton GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007409///axonogenesis+++GO:0022898///regulation of transmembrane transporter activity+++GO:0032091///negative regulation of protein binding+++GO:0034333///adherens junction assembly+++GO:0045176///apical protein localization+++GO:0048488///synaptic vesicle endocytosis+++GO:0048870///cell motility+++GO:0051621///regulation of norepinephrine uptake+++GO:0071257///cellular response to electrical stimulus+++GO:0071896///protein localization to adherens junction+++GO:0072749///cellular response to cytochalasin B+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity 114615 114615 'Elac1' mRNA 484 498 553 4.85 4.86 5.98 3.26 3.53 3.42 5.23 3.403333333 372 400 371 511.6666667 381 0.001437579 -0.439946101 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0042781///3'-tRNA processing endoribonuclease activity+++GO:0046872///metal ion binding" "GO:0008033///tRNA processing+++GO:0034414///tRNA 3'-trailer cleavage, endonucleolytic+++GO:0042779///tRNA 3'-trailer cleavage+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 11464 11464 'Actc1' mRNA 0 0 1 0 0 0.04 0.04 0 0.04 0.013333333 0.026666667 1 0 1 0.333333333 0.666666667 0.863090843 0.873488313 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0005884///actin filament+++GO:0030017///sarcomere+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031674///I band+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017022///myosin binding GO:0007015///actin filament organization+++GO:0010628///positive regulation of gene expression+++GO:0030048///actin filament-based movement+++GO:0030240///skeletal muscle thin filament assembly+++GO:0031032///actomyosin structure organization+++GO:0033275///actin-myosin filament sliding+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0055003///cardiac myofibril assembly+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060047///heart contraction+++GO:0060048///cardiac muscle contraction+++GO:0070252///actin-mediated cell contraction+++GO:0090131///mesenchyme migration 114641 114641 'Rpl31' mRNA 1634.02 1608.44 1818.47 95.6 92.51 113.07 112.54 114.35 120.59 100.3933333 115.8266667 2178.28 2184.82 2258.46 1686.976667 2207.186667 3.40E-05 0.372459962 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0002181///cytoplasmic translation+++GO:0006412///translation 114642 114642 'Brdt' mRNA 62.75 77.68 43.45 0.66 0.81 0.49 0.57 0.4 0.48 0.653333333 0.483333333 61.92 42.91 49.03 61.29333333 51.28666667 0.538593357 -0.265097278 GO:0000785///chromatin+++GO:0005634///nucleus GO:0005515///protein binding+++GO:0031493///nucleosomal histone binding+++GO:0042393///histone binding+++GO:0070577///lysine-acetylated histone binding "GO:0001207///histone displacement+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0043484///regulation of RNA splicing+++GO:0051039///positive regulation of transcription involved in meiotic cell cycle+++GO:0051321///meiotic cell cycle" 114643 114643 'Oas1c' mRNA 158 152 142 4.86 4.99 4.78 3.59 3.79 3.32 4.876666667 3.566666667 148 144 125 150.6666667 139 0.630289688 -0.127341518 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 114644 114644 'Slc13a3' mRNA 2524 2578 2367 42.79 43.01 42.57 95.2 96.52 97.47 42.79 96.39666667 6461 6398 6406 2489.666667 6421.666667 4.66E-138 1.356311001 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005310///dicarboxylic acid transmembrane transporter activity+++GO:0005343///organic acid:sodium symporter activity+++GO:0015137///citrate transmembrane transporter activity+++GO:0015139///alpha-ketoglutarate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015362///high-affinity sodium:dicarboxylate symporter activity+++GO:0017153///sodium:dicarboxylate symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0034634///glutathione transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006835///dicarboxylic acid transport+++GO:0015742///alpha-ketoglutarate transport+++GO:0015744///succinate transport+++GO:0015746///citrate transport+++GO:0015810///aspartate transmembrane transport+++GO:0034775///glutathione transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070778///L-aspartate transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0098656///anion transmembrane transport 11465 11465 'Actg1' mRNA 26439 27041.98 25511 793.12 799.31 811.86 1164.35 1053.58 1171.94 801.43 1129.956667 44618.17 39411 43463.42 26330.66 42497.53 1.22E-40 0.678177686 04015///Rap1 signaling pathway+++04145///Phagosome+++04210///Apoptosis+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04745///Phototransduction - fly+++04810///Regulation of actin cytoskeleton+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion+++05014///Amyotrophic lateral sclerosis+++05100///Bacterial invasion of epithelial cells+++05110///Vibrio cholerae infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05164///Influenza A+++05205///Proteoglycans in cancer+++05225///Hepatocellular carcinoma+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril+++GO:0031941///filamentous actin+++GO:0043034///costamere+++GO:0043209///myelin sheath+++GO:0043296///apical junction complex+++GO:0044305///calyx of Held+++GO:0045177///apical part of cell+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome+++GO:0097433///dense body+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0099143///presynaptic actin cytoskeleton GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0005524///ATP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0098973///structural constituent of postsynaptic actin cytoskeleton GO:0001525///angiogenesis+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0009612///response to mechanical stimulus+++GO:0010628///positive regulation of gene expression+++GO:0030335///positive regulation of cell migration+++GO:0045214///sarcomere organization+++GO:0048488///synaptic vesicle endocytosis+++GO:0051492///regulation of stress fiber assembly+++GO:0051592///response to calcium ion+++GO:0051893///regulation of focal adhesion assembly+++GO:0071346///cellular response to interferon-gamma+++GO:0090303///positive regulation of wound healing+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0120192///tight junction assembly+++GO:1902396///protein localization to bicellular tight junction 114654 114654 'Ly6g6d' mRNA 71 73.73 73 7.79 8.1 8.5 9.67 11.83 10.45 8.13 10.65 99.33 121.91 107 72.57666667 109.4133333 0.035385961 0.580873875 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0042802///identical protein binding GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 114663 114663 'Impa2' mRNA 24 24 23 0.8 0.79 0.81 2.81 3.63 3.78 0.8 3.406666667 97 122 126 23.66666667 115 1.68E-12 2.271837995 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm GO:0008934///inositol monophosphate 1-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0052832///inositol monophosphate 3-phosphatase activity+++GO:0052833///inositol monophosphate 4-phosphatase activity+++GO:0052834///inositol monophosphate phosphatase activity GO:0006020///inositol metabolic process+++GO:0006021///inositol biosynthetic process+++GO:0007165///signal transduction+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046855///inositol phosphate dephosphorylation 114664 114664 'Hsd17b11' mRNA 993 974 728 33.93 32.81 26.39 28.04 26.69 30.58 31.04333333 28.43666667 943 876 995 898.3333333 938 0.703836389 0.056087246 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet "GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006710///androgen catabolic process 114671 114671 '4930444G20Rik' mRNA 26.06 16.96 17.9 0.85 0.55 0.62 0.62 0.41 0.36 0.673333333 0.463333333 21.88 13.99 12.23 20.30666667 16.03333333 0.624840695 -0.372967655 03013///Nucleocytoplasmic transport+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005829///cytosol GO:0008234///cysteine-type peptidase activity+++GO:0016929///SUMO-specific protease activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization 114674 114674 'Gtf2ird2' mRNA 452 425 468 5.84 5.56 6.61 3.18 3.43 3.31 6.003333333 3.306666667 283 292 299 448.3333333 291.3333333 5.38E-06 -0.635601969 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0005515///protein binding GO:0014883///transition between fast and slow fiber 114679 114679 'Selenom' mRNA 2103 2030 2056 155.81 148.9 161.64 106.71 116.5 110.61 155.45 111.2733333 1650 1755 1652 2063 1685.666667 1.26E-04 -0.303399999 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm GO:0016491///oxidoreductase activity GO:0010269///response to selenium ion+++GO:0035264///multicellular organism growth+++GO:0035934///corticosterone secretion+++GO:0042445///hormone metabolic process+++GO:0060612///adipose tissue development 11468 11468 'Actg2' mRNA 8 20 10 0.37 0.91 0.49 1.04 1.27 0.62 0.59 0.976666667 26 31 15 12.66666667 24 0.18167691 0.918969609 04270///Vascular smooth muscle contraction GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0032982///myosin filament+++GO:0044297///cell body+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0005524///ATP binding GO:0010628///positive regulation of gene expression+++GO:0090131///mesenchyme migration 11470 11470 'Actl7a' mRNA 0 0 1 0 0 0.04 0.17 0 0 0.013333333 0.056666667 5 0 0 0.333333333 1.666666667 0.559651535 2.175682071 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0031514///motile cilium+++GO:0032991///protein-containing complex 11471 11471 'Actl7b' mRNA 2 1 2 0.08 0.04 0.09 0 0 0.04 0.07 0.013333333 0 0 1 1.666666667 0.333333333 0.460116667 -2.238830333 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex 114713 114713 'Rasa2' mRNA 520 533 487 4.99 5.11 5.37 5.1 4.82 4.78 5.156666667 4.9 591 528 513 513.3333333 544 0.625198426 0.072052027 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++05203///Viral carcinogenesis GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction 114714 114714 'Rad51c' mRNA 162.42 153 170 3.16 2.99 4.7 2.7 1.85 2.35 3.616666667 2.3 130 99 114 161.8066667 114.3333333 0.023989881 -0.515939117 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0033063///Rad51B-Rad51C-Rad51D-XRCC2 complex+++GO:0033065///Rad51C-XRCC3 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0048476///Holliday junction resolvase complex GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008821///crossover junction endodeoxyribonuclease activity GO:0000707///meiotic DNA recombinase assembly+++GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007066///female meiosis sister chromatid cohesion+++GO:0007131///reciprocal meiotic recombination+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle 114715 114715 'Spred1' mRNA 616 666 517 5.27 5.57 4.66 5.58 4.72 5.01 5.166666667 5.103333333 754 616 640 599.6666667 670 0.258893079 0.150618208 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity "GO:0000188///inactivation of MAPK activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010923///negative regulation of phosphatase activity+++GO:0016525///negative regulation of angiogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0043409///negative regulation of MAPK cascade+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0090311///regulation of protein deacetylation+++GO:1902747///negative regulation of lens fiber cell differentiation" 114716 114716 'Spred2' mRNA 2045.54 2101.82 1710.91 6.57 6.5 4.85 2.94 2.5 2.87 5.973333333 2.77 1246.64 976.18 1127.27 1952.756667 1116.696667 1.63E-19 -0.816088308 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity "GO:0000188///inactivation of MAPK activity+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0043086///negative regulation of catalytic activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090311///regulation of protein deacetylation+++GO:1902747///negative regulation of lens fiber cell differentiation" 11472 11472 'Actn2' mRNA 35 51 51 0.64 0.97 1.05 0.26 0.26 0.21 0.886666667 0.243333333 16 14 13 45.66666667 14.33333333 4.20E-04 -1.688134057 05412///Arrhythmogenic right ventricular cardiomyopathy "GO:0005737///cytoplasm+++GO:0005865///striated muscle thin filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding+++GO:0030274///LIM domain binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0030674///protein binding, bridging+++GO:0031432///titin binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051373///FATZ binding+++GO:0070080///titin Z domain binding" "GO:0006936///muscle contraction+++GO:0030035///microspike assembly+++GO:0030036///actin cytoskeleton organization+++GO:0042391///regulation of membrane potential+++GO:0043267///negative regulation of potassium ion transport+++GO:0043268///positive regulation of potassium ion transport+++GO:0045214///sarcomere organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048041///focal adhesion assembly+++GO:0051695///actin filament uncapping+++GO:0055001///muscle cell development+++GO:0055013///cardiac muscle cell development+++GO:0072659///protein localization to plasma membrane+++GO:0086097///phospholipase C-activating angiotensin-activated signaling pathway+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2001137///positive regulation of endocytic recycling+++GO:2001259///positive regulation of cation channel activity" 11474 11474 'Actn3' mRNA 9 21 24 0.17 0.39 0.49 0.33 0.22 0.21 0.35 0.253333333 20 13 12 18 15 0.741082698 -0.288249358 05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005865///striated muscle thin filament+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005925///focal adhesion+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding" GO:0001649///osteoblast differentiation+++GO:0006936///muscle contraction+++GO:0014728///regulation of the force of skeletal muscle contraction+++GO:0014732///skeletal muscle atrophy+++GO:0014883///transition between fast and slow fiber+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0030036///actin cytoskeleton organization+++GO:0031448///positive regulation of fast-twitch skeletal muscle fiber contraction+++GO:0045820///negative regulation of glycolytic process+++GO:0048041///focal adhesion assembly+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0055001///muscle cell development+++GO:0060349///bone morphogenesis+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0090257///regulation of muscle system process+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900159///positive regulation of bone mineralization involved in bone maturation+++GO:1901078///negative regulation of relaxation of muscle+++GO:1903715///regulation of aerobic respiration+++GO:1904025///positive regulation of glucose catabolic process to lactate via pyruvate 114741 114741 'Supt16' mRNA 1893.11 1727.87 1907.57 22.63 20.31 24.18 24.48 22.83 22.45 22.37333333 23.25333333 2358.07 2148.58 2094.51 1842.85 2200.386667 0.005851123 0.240908361 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0035101///FACT complex GO:0031491///nucleosome binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034724///DNA replication-independent nucleosome organization 11475 11475 'Acta2' mRNA 82 94 82 2.53 2.76 2.82 4.59 3.42 4.59 2.703333333 4.2 179 136 154 86 156.3333333 2.69E-04 0.849529936 04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04926///Relaxin signaling pathway GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030485///smooth muscle contractile fiber+++GO:0032991///protein-containing complex+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding GO:0006936///muscle contraction+++GO:0008217///regulation of blood pressure+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0014829///vascular smooth muscle contraction+++GO:0061041///regulation of wound healing+++GO:0061870///positive regulation of hepatic stellate cell migration+++GO:0061874///positive regulation of hepatic stellate cell contraction+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072144///glomerular mesangial cell development+++GO:0090131///mesenchyme migration+++GO:2000491///positive regulation of hepatic stellate cell activation 11477 11477 'Acvr1' mRNA 424 420 430 8.18 7.97 8.77 7.81 8.2 8.12 8.306666667 8.043333333 461 484 465 424.6666667 470 0.359491465 0.134030939 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0045177///apical part of cell+++GO:0048179///activin receptor complex+++GO:0070724///BMP receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016361///activin receptor activity, type I+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding+++GO:1990782///protein tyrosine kinase binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001655///urogenital system development+++GO:0001701///in utero embryonic development+++GO:0001702///gastrulation with mouth forming second+++GO:0001707///mesoderm formation+++GO:0001755///neural crest cell migration+++GO:0002526///acute inflammatory response+++GO:0003143///embryonic heart tube morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003274///endocardial cushion fusion+++GO:0003289///atrial septum primum morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007281///germ cell development+++GO:0007368///determination of left/right symmetry+++GO:0007369///gastrulation+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0009790///embryo development+++GO:0009953///dorsal/ventral pattern formation+++GO:0009968///negative regulation of signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030278///regulation of ossification+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0032924///activin receptor signaling pathway+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051145///smooth muscle cell differentiation+++GO:0060037///pharyngeal system development+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060412///ventricular septum morphogenesis+++GO:0060923///cardiac muscle cell fate commitment+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0061445///endocardial cushion cell fate commitment+++GO:0071363///cellular response to growth factor stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:2000017///positive regulation of determination of dorsal identity+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 114774 114774 'Pawr' mRNA 309 330 143 7.52 7.96 3.67 3.92 2.82 3.48 6.383333333 3.406666667 186 131 160 260.6666667 159 0.006333972 -0.711651576 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019899///enzyme binding+++GO:0043522///leucine zipper domain binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0030889///negative regulation of B cell proliferation+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0032623///interleukin-2 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0042986///positive regulation of amyloid precursor protein biosynthetic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045760///positive regulation of action potential+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051017///actin filament bundle assembly+++GO:0060450///positive regulation of hindgut contraction+++GO:0090281///negative regulation of calcium ion import+++GO:0097190///apoptotic signaling pathway+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0098703///calcium ion import across plasma membrane+++GO:1901082///positive regulation of relaxation of smooth muscle+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1904457///positive regulation of neuronal action potential+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000774///positive regulation of cellular senescence 11479 11479 'Acvr1b' mRNA 223 239 206 2.71 2.86 2.66 2.65 2.49 2.33 2.743333333 2.49 251 230 213 222.6666667 231.3333333 0.859900855 0.044433764 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0048179///activin receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016361///activin receptor activity, type I+++GO:0016740///transferase activity+++GO:0017002///activin-activated receptor activity+++GO:0019838///growth factor binding+++GO:0034711///inhibin binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001701///in utero embryonic development+++GO:0001942///hair follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0007498///mesoderm development+++GO:0009790///embryo development+++GO:0009966///regulation of signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0032924///activin receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0038092///nodal signaling pathway+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046545///development of primary female sexual characteristics+++GO:0046777///protein autophosphorylation+++GO:0071363///cellular response to growth factor stimulus+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1901165///positive regulation of trophoblast cell migration" 11480 11480 'Acvr2a' mRNA 526.47 512.59 489.04 5.21 5.12 5.23 3.06 2.68 3 5.186666667 2.913333333 361.8 307.73 333.2 509.3666667 334.2433333 8.37E-07 -0.621606074 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034673///inhibin-betaglycan-ActRII complex+++GO:0043235///receptor complex+++GO:0048179///activin receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015026///coreceptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017002///activin-activated receptor activity+++GO:0019838///growth factor binding+++GO:0030165///PDZ domain binding+++GO:0034711///inhibin binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0098821///BMP receptor activity GO:0001702///gastrulation with mouth forming second+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007283///spermatogenesis+++GO:0007368///determination of left/right symmetry+++GO:0007498///mesoderm development+++GO:0008584///male gonad development+++GO:0009952///anterior/posterior pattern specification+++GO:0009966///regulation of signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0032924///activin receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042713///sperm ejaculation+++GO:0043084///penile erection+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048706///embryonic skeletal system development+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0060011///Sertoli cell proliferation+++GO:0071363///cellular response to growth factor stimulus+++GO:0071773///cellular response to BMP stimulus 11481 11481 'Acvr2b' mRNA 319 278 321 1.59 1.36 1.7 0.97 0.67 0.93 1.55 0.856666667 224 154 205 306 194.3333333 2.61E-04 -0.672188798 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0048179///activin receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017002///activin-activated receptor activity+++GO:0019838///growth factor binding+++GO:0034711///inhibin binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001702///gastrulation with mouth forming second+++GO:0001822///kidney development+++GO:0001946///lymphangiogenesis+++GO:0001974///blood vessel remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007389///pattern specification process+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0009749///response to glucose+++GO:0009791///post-embryonic development+++GO:0009952///anterior/posterior pattern specification+++GO:0009966///regulation of signal transduction+++GO:0016310///phosphorylation+++GO:0030073///insulin secretion+++GO:0030324///lung development+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0031016///pancreas development+++GO:0032147///activation of protein kinase activity+++GO:0032924///activin receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0035265///organ growth+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048617///embryonic foregut morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0060021///roof of mouth development+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060840///artery development+++GO:0060841///venous blood vessel development+++GO:0061298///retina vasculature development in camera-type eye+++GO:0071363///cellular response to growth factor stimulus+++GO:0120163///negative regulation of cold-induced thermogenesis" 11482 11482 'Acvrl1' mRNA 335 392 363 5.04 5.83 5.79 9.05 8.6 9.74 5.553333333 9.13 693 643 722 363.3333333 686 2.76E-14 0.904770142 04060///Cytokine-cytokine receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0070724///BMP receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016361///activin receptor activity, type I+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding+++GO:0098821///BMP receptor activity" "GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001946///lymphangiogenesis+++GO:0001974///blood vessel remodeling+++GO:0003203///endocardial cushion morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007507///heart development+++GO:0008015///blood circulation+++GO:0008217///regulation of blood pressure+++GO:0008285///negative regulation of cell proliferation+++GO:0009953///dorsal/ventral pattern formation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032924///activin receptor signaling pathway+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035912///dorsal aorta morphogenesis+++GO:0042118///endothelial cell activation+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060840///artery development+++GO:0060841///venous blood vessel development+++GO:0061154///endothelial tube morphogenesis+++GO:0061298///retina vasculature development in camera-type eye+++GO:0071363///cellular response to growth factor stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0090500///endocardial cushion to mesenchymal transition+++GO:2000279///negative regulation of DNA biosynthetic process" 11484 11484 'Aspa' mRNA 201 259 217 7.94 9.98 9.05 6.74 8.59 7.09 8.99 7.473333333 199 245 204 225.6666667 216 0.775354663 -0.071921447 "00250///Alanine, aspartate and glutamate metabolism+++00340///Histidine metabolism" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004046///aminoacylase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0019807///aspartoacylase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0006083///acetate metabolic process+++GO:0022010///central nervous system myelination+++GO:0048714///positive regulation of oligodendrocyte differentiation 114841036 114841036 'LOC114841036' mRNA 153.44 141.72 110.43 4.79 4.36 3.66 3.45 3.13 4.03 4.27 3.536666667 127 112.58 143.76 135.1966667 127.78 0.775354663 -0.088072385 11486 11486 'Ada' mRNA 26 31 28 0.89 1.04 1.01 8.79 8.58 8.07 0.98 8.48 296 282 263 28.33333333 280.3333333 1.50E-43 3.295081801 00230///Purine metabolism+++05340///Primary immunodeficiency GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0032839///dendrite cytoplasm+++GO:0043025///neuronal cell body+++GO:0060205///cytoplasmic vesicle lumen GO:0001883///purine nucleoside binding+++GO:0004000///adenosine deaminase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019239///deaminase activity+++GO:0046872///metal ion binding+++GO:0046936///deoxyadenosine deaminase activity "GO:0000255///allantoin metabolic process+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001821///histamine secretion+++GO:0001829///trophectodermal cell differentiation+++GO:0001889///liver development+++GO:0001890///placenta development+++GO:0002314///germinal center B cell differentiation+++GO:0002636///positive regulation of germinal center formation+++GO:0002686///negative regulation of leukocyte migration+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process+++GO:0006196///AMP catabolic process+++GO:0007155///cell adhesion+++GO:0007568///aging+++GO:0009117///nucleotide metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0010460///positive regulation of heart rate+++GO:0030324///lung development+++GO:0030890///positive regulation of B cell proliferation+++GO:0032261///purine nucleotide salvage+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0033197///response to vitamin E+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0042110///T cell activation+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043066///negative regulation of apoptotic process+++GO:0043103///hypoxanthine salvage+++GO:0043278///response to morphine+++GO:0044209///AMP salvage+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0045580///regulation of T cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046059///dAMP catabolic process+++GO:0046061///dATP catabolic process+++GO:0046085///adenosine metabolic process+++GO:0046101///hypoxanthine biosynthetic process+++GO:0046103///inosine biosynthetic process+++GO:0046111///xanthine biosynthetic process+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0048286///lung alveolus development+++GO:0048541///Peyer's patch development+++GO:0048566///embryonic digestive tract development+++GO:0050728///negative regulation of inflammatory response+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0060169///negative regulation of adenosine receptor signaling pathway+++GO:0060407///negative regulation of penile erection+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0070256///negative regulation of mucus secretion" 114863 114863 'Plpbp' mRNA 932 1042 1034 24.83 27.11 29.07 31.55 29.5 28.08 27.00333333 29.71 1342 1248 1190 1002.666667 1260 0.001138563 0.315650319 GO:0005622///intracellular+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0030170///pyridoxal phosphate binding 11487 11487 'Adam10' mRNA 3021 3220 2756 35.15 36.84 34.02 32.03 33.17 34.16 35.33666667 33.12 3169 3206 3273 2999 3216 0.206713095 0.091618707 04361///Axon regeneration+++05010///Alzheimer disease+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045211///postsynaptic membrane+++GO:0046930///pore complex+++GO:0062023///collagen-containing extracellular matrix+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0097060///synaptic membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:1902945///metalloendopeptidase activity involved in amyloid precursor protein catabolic process GO:0001701///in utero embryonic development+++GO:0006468///protein phosphorylation+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006913///nucleocytoplasmic transport+++GO:0007162///negative regulation of cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007229///integrin-mediated signaling pathway+++GO:0007283///spermatogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0008593///regulation of Notch signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0016485///protein processing+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0034205///amyloid-beta formation+++GO:0034332///adherens junction organization+++GO:0034612///response to tumor necrosis factor+++GO:0042117///monocyte activation+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0046931///pore complex assembly+++GO:0051089///constitutive protein ectodomain proteolysis+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0090102///cochlea development+++GO:0097327///response to antineoplastic agent+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0099173///postsynapse organization+++GO:1901342///regulation of vasculature development+++GO:1901998///toxin transport 114872 114872 'Psg29' mRNA 3.7 6 9 0.04 0.06 0.09 0.07 0.01 0.02 0.063333333 0.033333333 8 1 2.49 6.233333333 3.83 0.618866935 -0.753022335 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0008150///biological_process 114873 114873 'Dscaml1' mRNA 505 476 383 3.66 3.38 2.95 0.46 0.37 0.35 3.33 0.393333333 74 57 54 454.6666667 61.66666667 5.43E-55 -2.891025782 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0045202///synapse GO:0004550///nucleoside diphosphate kinase activity+++GO:0042803///protein homodimerization activity+++GO:0098632///cell-cell adhesion mediator activity GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0070593///dendrite self-avoidance 114874 114874 'Ddhd1' mRNA 560 568 505 5.82 5.79 5.54 5.29 4.49 4.24 5.716666667 4.673333333 583 482 454 544.3333333 506.3333333 0.432835356 -0.116247537 GO:0005737///cytoplasm GO:0004620///phospholipase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0030382///sperm mitochondrion organization+++GO:0090141///positive regulation of mitochondrial fission 11488 11488 'Adam11' mRNA 11643 11597 10847 123.2 120.43 121.67 10.42 9.59 8.82 121.7666667 9.61 1124 1018 928 11362.33333 1023.333333 0 -3.484874202 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis 114886 114886 'Cygb' mRNA 254 302 235 6.07 7.14 6 1.93 1.51 1.91 6.403333333 1.783333333 93 71 89 263.6666667 84.33333333 9.68E-17 -1.654271813 GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0004096///catalase activity+++GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0005506///iron ion binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0047888///fatty acid peroxidase activity GO:0001666///response to hypoxia+++GO:0006979///response to oxidative stress+++GO:0010764///negative regulation of fibroblast migration+++GO:0015671///oxygen transport+++GO:0019395///fatty acid oxidation+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0098869///cellular oxidant detoxification+++GO:2000490///negative regulation of hepatic stellate cell activation 11489 11489 'Adam12' mRNA 89 112 81 0.61 0.76 0.59 0.41 0.33 0.26 0.653333333 0.333333333 69 54 43 94 55.33333333 0.013693458 -0.774177309 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0045766///positive regulation of angiogenesis 114893 114893 'Dcun1d1' mRNA 1062.37 1100.42 1047.84 14.58 14.75 15.39 14.55 13.37 14.04 14.90666667 13.98666667 1210.56 1083.86 1129.88 1070.21 1141.433333 0.43631411 0.08024224 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032182///ubiquitin-like protein binding+++GO:0097602///cullin family protein binding GO:0031396///regulation of protein ubiquitination+++GO:0045116///protein neddylation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000434///regulation of protein neddylation+++GO:2000436///positive regulation of protein neddylation 114896 114896 'Afg3l1' mRNA 1142 1178 1009 21.18 21.15 19.74 21.92 23.45 20.1 20.69 21.82333333 1320 1345 1198 1109.666667 1287.666667 0.026257603 0.205384513 05017///Spinocerebellar ataxia GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005745///m-AAA complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007005///mitochondrion organization+++GO:0008053///mitochondrial fusion+++GO:0016485///protein processing+++GO:0034982///mitochondrial protein processing+++GO:0042407///cristae formation+++GO:0065003///protein-containing complex assembly 11490 11490 'Adam15' mRNA 2780 2990 2729 51.76 54.84 53.9 72.58 73.34 67.85 53.5 71.25666667 4455 4404 4050 2833 4303 1.83E-20 0.591813241 GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005912///adherens junction+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0070062///extracellular exosome GO:0004222///metalloendopeptidase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002418///immune response to tumor cell+++GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008584///male gonad development+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0042246///tissue regeneration+++GO:0045087///innate immune response+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:1900121///negative regulation of receptor binding+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:1990910///response to hypobaric hypoxia 11491 11491 'Adam17' mRNA 692 737 753 8.43 8.87 9.73 19.18 17.38 17.34 9.01 17.96666667 1807 1598 1588 727.3333333 1664.333333 5.85E-39 1.179812146 04330///Notch signaling pathway+++05010///Alzheimer disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0045121///membrane raft+++GO:0045177///apical part of cell GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005112///Notch binding+++GO:0005138///interleukin-6 receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding+++GO:1902945///metalloendopeptidase activity involved in amyloid precursor protein catabolic process "GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002467///germinal center formation+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007155///cell adhesion+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007229///integrin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0016485///protein processing+++GO:0030183///B cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032722///positive regulation of chemokine production+++GO:0033025///regulation of mast cell apoptotic process+++GO:0033077///T cell differentiation in thymus+++GO:0033627///cell adhesion mediated by integrin+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035624///receptor transactivation+++GO:0042493///response to drug+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0048536///spleen development+++GO:0048679///regulation of axon regeneration+++GO:0048870///cell motility+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051272///positive regulation of cellular component movement+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2001222///regulation of neuron migration" 11492 11492 'Adam19' mRNA 38 44 28 0.33 0.42 0.25 1.4 1.04 1.3 0.333333333 1.246666667 185 136 171 36.66666667 164 2.30E-15 2.152633001 GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding+++GO:1902945///metalloendopeptidase activity involved in amyloid precursor protein catabolic process GO:0001890///placenta development+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0016485///protein processing+++GO:0042987///amyloid precursor protein catabolic process+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin 11495 11495 'Adam2' mRNA 0 1 1 0 0.02 0.02 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0001669///acrosomal vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0008542///visual learning+++GO:0010628///positive regulation of gene expression+++GO:0030534///adult behavior 11496 11496 'Adam22' mRNA 1068 1201 1044 9.55 10.59 9.51 4.52 4.55 4.85 9.883333333 4.64 558 485 535 1104.333333 526 1.23E-28 -1.081220542 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0008344///adult locomotory behavior+++GO:0014037///Schwann cell differentiation+++GO:0022011///myelination in peripheral nervous system+++GO:0042063///gliogenesis+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 11497 11497 'Adam3' mRNA 1 2 1 0.02 0.05 0.03 0 0.05 0.05 0.033333333 0.033333333 0 3 2 1.333333333 1.666666667 0.896496682 0.33349029 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0061827///sperm head GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0009566///fertilization+++GO:0010628///positive regulation of gene expression+++GO:0030317///flagellated sperm motility+++GO:0050684///regulation of mRNA processing 11498 11498 'Adam4' mRNA 35.28 26 46.73 0.75 0.55 1.06 0.61 0.46 0.65 0.786666667 0.573333333 33 24 34 36.00333333 30.33333333 0.658742784 -0.257775315 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990913///sperm head plasma membrane GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0008584///male gonad development 11499 11499 'Adam5' mRNA 2 2 0 0.04 0.04 0 0 0 0.06 0.026666667 0.02 0 0 3 1.333333333 1 0.905938796 -0.388223419 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007339///binding of sperm to zona pellucida 11500 11500 'Adam7' mRNA 25 21 16 0.39 0.32 0.27 0 0 0.03 0.326666667 0.01 0 0 2 20.66666667 0.666666667 1.34E-04 -4.958229889 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis 11501 11501 'Adam8' mRNA 80 62 78 1.41 1.03 1.45 35.4 32.81 33.87 1.296666667 34.02666667 2322 2101 2152 73.33333333 2191.666667 0 4.888570957 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032010///phagolysosome+++GO:0032127///dense core granule membrane+++GO:0042581///specific granule+++GO:0070820///tertiary granule+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex GO:0004222///metalloendopeptidase activity+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding GO:0000902///cell morphogenesis+++GO:0001525///angiogenesis+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0002693///positive regulation of cellular extravasation+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0022407///regulation of cell-cell adhesion+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043534///blood vessel endothelial cell migration+++GO:0045089///positive regulation of innate immune response+++GO:0045670///regulation of osteoclast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0048247///lymphocyte chemotaxis+++GO:0048729///tissue morphogenesis+++GO:0050729///positive regulation of inflammatory response+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061025///membrane fusion+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:0072675///osteoclast fusion+++GO:0098609///cell-cell adhesion+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000399///negative regulation of thymocyte aggregation+++GO:2000406///positive regulation of T cell migration+++GO:2000415///positive regulation of fibronectin-dependent thymocyte migration+++GO:2000418///positive regulation of eosinophil migration 11502 11502 'Adam9' mRNA 684 756 692 9.21 10.04 9.91 31.1 32.54 34.32 9.72 32.65333333 2651 2710 2834 710.6666667 2731.666667 8.59E-135 1.931837128 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031233///intrinsic component of external side of plasma membrane GO:0004222///metalloendopeptidase activity+++GO:0005080///protein kinase C binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0043236///laminin binding+++GO:0046872///metal ion binding+++GO:1902945///metalloendopeptidase activity involved in amyloid precursor protein catabolic process GO:0000186///activation of MAPKK activity+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010042///response to manganese ion+++GO:0016477///cell migration+++GO:0016485///protein processing+++GO:0030335///positive regulation of cell migration+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0033627///cell adhesion mediated by integrin+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034241///positive regulation of macrophage fusion+++GO:0034612///response to tumor necrosis factor+++GO:0034616///response to laminar fluid shear stress+++GO:0042117///monocyte activation+++GO:0042542///response to hydrogen peroxide+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050714///positive regulation of protein secretion+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051384///response to glucocorticoid+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051592///response to calcium ion+++GO:0071222///cellular response to lipopolysaccharide+++GO:0097327///response to antineoplastic agent 11504 11504 'Adamts1' mRNA 349 426 423 3.82 4.59 4.91 20.41 18.76 19.71 4.44 19.62666667 2146 1927 2007 399.3333333 2026.666667 7.33E-125 2.329261221 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0031012///extracellular matrix+++GO:0031410///cytoplasmic vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001542///ovulation from ovarian follicle+++GO:0001822///kidney development+++GO:0006508///proteolysis+++GO:0010976///positive regulation of neuron projection development+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0060347///heart trabecula formation+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration 11512 11512 'Adcy6' mRNA 1032.64 1043.08 912.01 8.75 8.85 8.26 6.8 5.53 6.19 8.62 6.173333333 903.63 722.16 798.08 995.91 807.9566667 0.00218962 -0.313275481 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031528///microvillus membrane+++GO:0032420///stereocilium+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0045121///membrane raft GO:0000149///SNARE binding+++GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005080///protein kinase C binding+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding GO:0003091///renal water homeostasis+++GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010977///negative regulation of neuron projection development+++GO:0035556///intracellular signal transduction+++GO:0035811///negative regulation of urine volume+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071870///cellular response to catecholamine stimulus+++GO:0072660///maintenance of protein location in plasma membrane+++GO:0097746///regulation of blood vessel diameter+++GO:1904117///cellular response to vasopressin+++GO:1904322///cellular response to forskolin 11513 11513 'Adcy7' mRNA 130 175 162 1.34 1.66 1.71 13.83 12.37 13.32 1.57 13.17333333 1552 1395 1429 155.6666667 1458.666667 5.38E-164 3.215216112 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0046872///metal ion binding GO:0002819///regulation of adaptive immune response+++GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0060135///maternal process involved in female pregnancy+++GO:0071285///cellular response to lithium ion+++GO:0071361///cellular response to ethanol+++GO:1900016///negative regulation of cytokine production involved in inflammatory response 11514 11514 'Adcy8' mRNA 447 511 485 4.8 5.43 5.5 0.58 0.47 0.52 5.243333333 0.523333333 61 50 54 481 55 3.53E-67 -3.141933222 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0004016///adenylate cyclase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0019902///phosphatase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0047485///protein N-terminus binding+++GO:0051721///protein phosphatase 2A binding GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007613///memory+++GO:0007616///long-term memory+++GO:0007626///locomotory behavior+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010255///glucose mediated signaling pathway+++GO:0019933///cAMP-mediated signaling+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0034199///activation of protein kinase A activity+++GO:0035556///intracellular signal transduction+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0038003///opioid receptor signaling pathway+++GO:0042593///glucose homeostasis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051259///protein complex oligomerization+++GO:0051260///protein homooligomerization+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0071277///cellular response to calcium ion+++GO:0071315///cellular response to morphine+++GO:0071333///cellular response to glucose stimulus+++GO:0071377///cellular response to glucagon stimulus+++GO:0080135///regulation of cellular response to stress+++GO:0150076///neuroinflammatory response+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1904322///cellular response to forskolin 11515 11515 'Adcy9' mRNA 749 812 636 5.36 5.76 4.96 3.1 2.9 3.02 5.36 3.006666667 489 449 467 732.3333333 468.3333333 4.35E-09 -0.653316317 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05110///Vibrio cholerae infection+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway 11516 11516 'Adcyap1' mRNA 0 2 1 0 0.03 0.04 0.03 0.01 0 0.023333333 0.013333333 1 1 0 1 0.666666667 0.863090843 -0.594301275 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04911///Insulin secretion+++04924///Renin secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043204///perikaryon GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0016521///pituitary adenylate cyclase activating polypeptide activity+++GO:0031858///pituitary adenylate cyclase-activating polypeptide receptor binding+++GO:0051428///peptide hormone receptor binding "GO:0001541///ovarian follicle development+++GO:0001662///behavioral fear response+++GO:0001821///histamine secretion+++GO:0001932///regulation of protein phosphorylation+++GO:0002865///negative regulation of acute inflammatory response to antigenic stimulus+++GO:0002878///negative regulation of acute inflammatory response to non-antigenic stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0007399///nervous system development+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0019233///sensory perception of pain+++GO:0019933///cAMP-mediated signaling+++GO:0021983///pituitary gland development+++GO:0030073///insulin secretion+++GO:0031175///neuron projection development+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032880///regulation of protein localization+++GO:0034260///negative regulation of GTPase activity+++GO:0042311///vasodilation+++GO:0042594///response to starvation+++GO:0043267///negative regulation of potassium ion transport+++GO:0043547///positive regulation of GTPase activity+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045471///response to ethanol+++GO:0045786///negative regulation of cell cycle+++GO:0045860///positive regulation of protein kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046034///ATP metabolic process+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060124///positive regulation of growth hormone secretion+++GO:0060253///negative regulation of glial cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:0090274///positive regulation of somatostatin secretion+++GO:0120162///positive regulation of cold-induced thermogenesis" 11517 11517 'Adcyap1r1' mRNA 51 61 68 0.43 0.51 0.62 1.06 0.98 0.9 0.52 0.98 144 128 118 60 130 3.71E-05 1.098955948 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04911///Insulin secretion+++04924///Renin secretion GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004999///vasoactive intestinal polypeptide receptor activity+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0031267///small GTPase binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0019933///cAMP-mediated signaling+++GO:0030154///cell differentiation+++GO:0032355///response to estradiol+++GO:0033555///multicellular organismal response to stress+++GO:0042493///response to drug+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045471///response to ethanol+++GO:0046545///development of primary female sexual characteristics+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0060548///negative regulation of cell death+++GO:0060732///positive regulation of inositol phosphate biosynthetic process 11518 11518 'Add1' mRNA 2949 2982 2898 39.13 39.09 40.89 36.22 36.44 33.91 39.70333333 35.52333333 3144 3078 2851 2943 3024.333333 0.768693626 0.027059956 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0008290///F-actin capping protein complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005516///calmodulin binding+++GO:0008134///transcription factor binding+++GO:0030507///spectrin binding+++GO:0042608///T cell receptor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0006884///cell volume homeostasis+++GO:0020027///hemoglobin metabolic process+++GO:0030218///erythrocyte differentiation+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032092///positive regulation of protein binding+++GO:0035264///multicellular organism growth+++GO:0045766///positive regulation of angiogenesis+++GO:0045807///positive regulation of endocytosis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051016///barbed-end actin filament capping+++GO:0051017///actin filament bundle assembly+++GO:0071277///cellular response to calcium ion+++GO:0071300///cellular response to retinoic acid+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:1903393///positive regulation of adherens junction organization 11519 11519 'Add2' mRNA 62 71 62 0.55 0.8 0.69 1.89 1.97 2.28 0.68 2.046666667 227 213 225 65 221.6666667 6.53E-17 1.758997153 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008290///F-actin capping protein complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044853///plasma membrane raft+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005516///calmodulin binding+++GO:0019901///protein kinase binding+++GO:0030507///spectrin binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding GO:0006811///ion transport+++GO:0007416///synapse assembly+++GO:0030097///hemopoiesis+++GO:0032092///positive regulation of protein binding+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0051016///barbed-end actin filament capping+++GO:0051017///actin filament bundle assembly+++GO:0065003///protein-containing complex assembly 11520 11520 'Plin2' mRNA 479 509 510 14.64 15.52 16.44 137.34 141.29 133.31 15.53333333 137.3133333 5123 5144 4833 499.3333333 5033.333333 0 3.321198665 03320///PPAR signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding GO:0010890///positive regulation of sequestering of triglyceride+++GO:0014070///response to organic cyclic compound+++GO:0015909///long-chain fatty acid transport+++GO:0019915///lipid storage+++GO:0042493///response to drug 11522 11522 'Adh1' mRNA 109 123 129 4.65 5.17 5.83 9.88 10.54 10.21 5.216666667 10.21 266 277 266 120.3333333 269.6666667 3.61E-10 1.150781861 00010///Glycolysis / Gluconeogenesis+++00071///Fatty acid degradation+++00350///Tyrosine metabolism+++00620///Pyruvate metabolism+++00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04936///Alcoholic liver disease GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0004024///alcohol dehydrogenase activity, zinc-dependent+++GO:0004745///retinol dehydrogenase activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0018455///alcohol dehydrogenase [NAD(P)+] activity+++GO:0035276///ethanol binding+++GO:0036094///small molecule binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051287///NAD binding+++GO:0097159///organic cyclic compound binding" GO:0001523///retinoid metabolic process+++GO:0006068///ethanol catabolic process+++GO:0006069///ethanol oxidation+++GO:0032526///response to retinoic acid+++GO:0033574///response to testosterone+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0046186///acetaldehyde biosynthetic process+++GO:0048149///behavioral response to ethanol+++GO:0048545///response to steroid hormone 11529 11529 'Adh7' mRNA 0 0 1 0 0 0.03 0.07 0.1 0.05 0.01 0.073333333 3 4 2 0.333333333 3 0.196721821 3.056057446 00010///Glycolysis / Gluconeogenesis+++00071///Fatty acid degradation+++00350///Tyrosine metabolism+++00620///Pyruvate metabolism+++00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04936///Alcoholic liver disease GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0003960///NADPH:quinone reductase activity+++GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0004024///alcohol dehydrogenase activity, zinc-dependent+++GO:0004031///aldehyde oxidase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0005503///all-trans retinal binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0018455///alcohol dehydrogenase [NAD(P)+] activity+++GO:0019115///benzaldehyde dehydrogenase activity+++GO:0019841///retinol binding+++GO:0035276///ethanol binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048019///receptor antagonist activity+++GO:0050153///omega-hydroxydecanoate dehydrogenase activity+++GO:0051287///NAD binding+++GO:0051903///S-(hydroxymethyl)glutathione dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0006066///alcohol metabolic process+++GO:0006067///ethanol metabolic process+++GO:0006068///ethanol catabolic process+++GO:0006069///ethanol oxidation+++GO:0006081///cellular aldehyde metabolic process+++GO:0009617///response to bacterium+++GO:0010430///fatty acid omega-oxidation+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0045471///response to ethanol+++GO:0046164///alcohol catabolic process+++GO:0046294///formaldehyde catabolic process+++GO:1901661///quinone metabolic process+++GO:2000272///negative regulation of signaling receptor activity 11532 11532 'Adh5' mRNA 2080 2039 1937 75.88 73.35 74.97 91.03 97.45 87.82 74.73333333 92.1 2867 2995 2676 2018.666667 2846 1.18E-11 0.484698829 00010///Glycolysis / Gluconeogenesis+++00071///Fatty acid degradation+++00350///Tyrosine metabolism+++00620///Pyruvate metabolism+++00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++01200///Carbon metabolism+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0004024///alcohol dehydrogenase activity, zinc-dependent+++GO:0005504///fatty acid binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0018455///alcohol dehydrogenase [NAD(P)+] activity+++GO:0018467///formaldehyde dehydrogenase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051903///S-(hydroxymethyl)glutathione dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0003016///respiratory system process+++GO:0006068///ethanol catabolic process+++GO:0006069///ethanol oxidation+++GO:0010430///fatty acid omega-oxidation+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0032496///response to lipopolysaccharide+++GO:0045777///positive regulation of blood pressure+++GO:0046294///formaldehyde catabolic process+++GO:0051409///response to nitrosative stress+++GO:0051775///response to redox state 11534 11534 'Adk' mRNA 1022 1069 1115 31.6 32.82 36.62 28.06 27.74 27.69 33.68 27.83 1050 1011 1000 1068.666667 1020.333333 0.483502807 -0.080896259 00230///Purine metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000166///nucleotide binding+++GO:0004001///adenosine kinase activity+++GO:0004136///deoxyadenosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0046872///metal ion binding" GO:0006166///purine ribonucleoside salvage+++GO:0006175///dATP biosynthetic process+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0016310///phosphorylation+++GO:0032263///GMP salvage+++GO:0042102///positive regulation of T cell proliferation+++GO:0044209///AMP salvage+++GO:0044342///type B pancreatic cell proliferation+++GO:0046085///adenosine metabolic process 11535 11535 'Adm' mRNA 152 147 132 6.52 6.22 6.01 43.69 44.13 44.13 6.25 43.98333333 1170 1153 1143 143.6666667 1155.333333 3.71E-147 2.99731071 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005179///hormone activity+++GO:0031700///adrenomedullin receptor binding GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001843///neural tube closure+++GO:0002026///regulation of the force of heart contraction+++GO:0002031///G protein-coupled receptor internalization+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0008209///androgen metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009409///response to cold+++GO:0009611///response to wounding+++GO:0010033///response to organic substance+++GO:0010460///positive regulation of heart rate+++GO:0019731///antibacterial humoral response+++GO:0019933///cAMP-mediated signaling+++GO:0031100///animal organ regeneration+++GO:0031102///neuron projection regeneration+++GO:0031623///receptor internalization+++GO:0032496///response to lipopolysaccharide+++GO:0032868///response to insulin+++GO:0035809///regulation of urine volume+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042594///response to starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0043116///negative regulation of vascular permeability+++GO:0045766///positive regulation of angiogenesis+++GO:0045906///negative regulation of vasoconstriction+++GO:0046879///hormone secretion+++GO:0048589///developmental growth+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051384///response to glucocorticoid+++GO:0055074///calcium ion homeostasis+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060712///spongiotrophoblast layer development+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0097084///vascular smooth muscle cell development+++GO:0097647///amylin receptor signaling pathway+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2001214///positive regulation of vasculogenesis 11536 11536 'Gpr182' mRNA 436 392 365 14.95 13.25 13.28 15.43 13.48 15.97 13.82666667 14.96 517 441 518 397.6666667 492 0.029603954 0.296026786 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001605///adrenomedullin receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 11538 11538 'Adnp' mRNA 952 1010 809 10.31 10.78 9.43 8.7 7.85 8.55 10.17333333 8.366666667 911 808 868 923.6666667 862.3333333 0.339890411 -0.108092119 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0090575///RNA polymerase II transcription factor complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding GO:0007614///short-term memory+++GO:0009743///response to carbohydrate+++GO:0010035///response to inorganic substance+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010835///regulation of protein ADP-ribosylation+++GO:0010976///positive regulation of neuron projection development+++GO:0019934///cGMP-mediated signaling+++GO:0031668///cellular response to extracellular stimulus+++GO:0032091///negative regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0033484///nitric oxide homeostasis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044849///estrous cycle+++GO:0045773///positive regulation of axon extension+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050805///negative regulation of synaptic transmission+++GO:0051965///positive regulation of synapse assembly 11539 11539 'Adora1' mRNA 340.89 397.88 419.94 3.21 3.82 4.27 4.36 3.97 3.84 3.766666667 4.056666667 511.79 459 442.79 386.2366667 471.1933333 0.070995862 0.272740451 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++05032///Morphine addiction GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0032279///asymmetric synapse+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044297///cell body+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048786///presynaptic active zone+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0001609///G protein-coupled adenosine receptor activity+++GO:0001664///G protein-coupled receptor binding+++GO:0001883///purine nucleoside binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0032795///heterotrimeric G-protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0099582///neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration "GO:0000186///activation of MAPKK activity+++GO:0001659///temperature homeostasis+++GO:0001666///response to hypoxia+++GO:0001973///adenosine receptor signaling pathway+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0002674///negative regulation of acute inflammatory response+++GO:0002686///negative regulation of leukocyte migration+++GO:0002793///positive regulation of peptide secretion+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003093///regulation of glomerular filtration+++GO:0006612///protein targeting to membrane+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0014050///negative regulation of glutamate secretion+++GO:0016042///lipid catabolic process+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032244///positive regulation of nucleoside transport+++GO:0032900///negative regulation of neurotrophin production+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035814///negative regulation of renal sodium excretion+++GO:0042311///vasodilation+++GO:0042321///negative regulation of circadian sleep/wake cycle, sleep+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0043066///negative regulation of apoptotic process+++GO:0043268///positive regulation of potassium ion transport+++GO:0043410///positive regulation of MAPK cascade+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045776///negative regulation of blood pressure+++GO:0045777///positive regulation of blood pressure+++GO:0045822///negative regulation of heart contraction+++GO:0046888///negative regulation of hormone secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050890///cognition+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050995///negative regulation of lipid catabolic process+++GO:0050996///positive regulation of lipid catabolic process+++GO:0051930///regulation of sensory perception of pain+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0055089///fatty acid homeostasis+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060079///excitatory postsynaptic potential+++GO:0060087///relaxation of vascular smooth muscle+++GO:0070256///negative regulation of mucus secretion+++GO:0070328///triglyceride homeostasis+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900453///negative regulation of long-term synaptic depression+++GO:1901216///positive regulation of neuron death" 11540 11540 'Adora2a' mRNA 11 12 12 0.26 0.28 0.3 0.25 0.46 0.21 0.28 0.306666667 13 22 10 11.66666667 15 0.695275057 0.353561974 04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++05012///Parkinson disease+++05034///Alcoholism GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0032279///asymmetric synapse+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0045211///postsynaptic membrane+++GO:0048786///presynaptic active zone+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0001609///G protein-coupled adenosine receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0019899///enzyme binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051393///alpha-actinin binding "GO:0001963///synaptic transmission, dopaminergic+++GO:0001973///adenosine receptor signaling pathway+++GO:0001975///response to amphetamine+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007271///synaptic transmission, cholinergic+++GO:0007626///locomotory behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0014049///positive regulation of glutamate secretion+++GO:0014057///positive regulation of acetylcholine secretion, neurotransmission+++GO:0014061///regulation of norepinephrine secretion+++GO:0031000///response to caffeine+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035810///positive regulation of urine volume+++GO:0035815///positive regulation of renal sodium excretion+++GO:0040013///negative regulation of locomotion+++GO:0042311///vasodilation+++GO:0042493///response to drug+++GO:0042755///eating behavior+++GO:0043116///negative regulation of vascular permeability+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043279///response to alkaloid+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045938///positive regulation of circadian sleep/wake cycle, sleep+++GO:0046636///negative regulation of alpha-beta T cell activation+++GO:0048143///astrocyte activation+++GO:0048812///neuron projection morphogenesis+++GO:0050714///positive regulation of protein secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051899///membrane depolarization+++GO:0051924///regulation of calcium ion transport+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0060134///prepulse inhibition+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2001235///positive regulation of apoptotic signaling pathway" 11541 11541 'Adora2b' mRNA 54 36 54 1.68 1.11 1.79 7.4 7.22 6.78 1.526666667 7.133333333 273 260 242 48 258.3333333 3.24E-26 2.412398884 04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++05034///Alcoholism GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0001609///G protein-coupled adenosine receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001973///adenosine receptor signaling pathway+++GO:0002882///positive regulation of chronic inflammatory response to non-antigenic stimulus+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010701///positive regulation of norepinephrine secretion+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0010893///positive regulation of steroid biosynthetic process+++GO:0010906///regulation of glucose metabolic process+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0031668///cellular response to extracellular stimulus+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033605///positive regulation of catecholamine secretion+++GO:0042311///vasodilation+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0060087///relaxation of vascular smooth muscle+++GO:1990776///response to angiotensin+++GO:2000300///regulation of synaptic vesicle exocytosis 11542 11542 'Adora3' mRNA 0 0 2 0 0 0.05 0.49 0.4 0.68 0.016666667 0.523333333 24 19 32 0.666666667 25 3.64E-05 5.205251494 04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031594///neuromuscular junction+++GO:0045202///synapse GO:0001609///G protein-coupled adenosine receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0001973///adenosine receptor signaling pathway+++GO:0002553///histamine secretion by mast cell+++GO:0002687///positive regulation of leukocyte migration+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030336///negative regulation of cell migration+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043306///positive regulation of mast cell degranulation+++GO:0050729///positive regulation of inflammatory response+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0070257///positive regulation of mucus secretion 11544 11544 'Adprh' mRNA 1784 1882 1792 66.07 68.73 70.41 64.21 67.25 66.8 68.40333333 66.08666667 1992 2036 2005 1819.333333 2011 0.09441126 0.132982564 GO:0005615///extracellular space+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0003875///ADP-ribosylarginine hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0046872///metal ion binding GO:0006464///cellular protein modification process+++GO:0051725///protein de-ADP-ribosylation 11545 11545 'Parp1' mRNA 1051 1142 1107 15.59 16.67 17.42 20.29 19.18 19.12 16.56 19.53 1574 1453 1436 1100 1487.666667 6.65E-07 0.422441988 03410///Base excision repair+++04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04212///Longevity regulating pathway - worm+++04214///Apoptosis - fly+++04217///Necroptosis+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0035861///site of double-strand break+++GO:0090734///site of DNA damage "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030331///estrogen receptor binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051287///NAD binding+++GO:0070412///R-SMAD binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0000723///telomere maintenance+++GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0006471///protein ADP-ribosylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007005///mitochondrion organization+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010332///response to gamma radiation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010990///regulation of SMAD protein complex assembly+++GO:0016540///protein autoprocessing+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:0018424///peptidyl-glutamic acid poly-ADP-ribosylation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030592///DNA ADP-ribosylation+++GO:0032042///mitochondrial DNA metabolic process+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032869///cellular response to insulin stimulus+++GO:0032880///regulation of protein localization+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0034599///cellular response to oxidative stress+++GO:0034644///cellular response to UV+++GO:0036211///protein modification process+++GO:0040009///regulation of growth rate+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0043504///mitochondrial DNA repair+++GO:0044030///regulation of DNA methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048148///behavioral response to cocaine+++GO:0050790///regulation of catalytic activity+++GO:0050882///voluntary musculoskeletal movement+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:0071294///cellular response to zinc ion+++GO:0071451///cellular response to superoxide+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901216///positive regulation of neuron death+++GO:1903376///regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903516///regulation of single strand break repair+++GO:1903518///positive regulation of single strand break repair+++GO:1903827///regulation of cellular protein localization+++GO:1904044///response to aldosterone+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1904646///cellular response to amyloid-beta+++GO:1904762///positive regulation of myofibroblast differentiation+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:1990966///ATP generation from poly-ADP-D-ribose+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2001170///negative regulation of ATP biosynthetic process" 11546 11546 'Parp2' mRNA 917.08 1036.38 1018.05 25 27.71 29.77 24.05 25.59 25.7 27.49333333 25.11333333 990.58 1010 1026.32 990.5033333 1008.966667 0.916000669 0.013717204 03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0090734///site of DNA damage "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0031491///nucleosome binding+++GO:1990404///protein ADP-ribosylase activity" GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0006471///protein ADP-ribosylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016570///histone modification+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:0030592///DNA ADP-ribosylation+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1901215///negative regulation of neuron death 11548 11548 'Adra1b' mRNA 61 55 33 1.04 0.91 0.6 0.25 0.46 0.2 0.85 0.303333333 17 30 13 49.66666667 20 0.006979698 -1.309877902 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04970///Salivary secretion GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004937///alpha1-adrenergic receptor activity+++GO:0046982///protein heterodimerization activity GO:0001974///blood vessel remodeling+++GO:0001975///response to amphetamine+++GO:0001987///vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure+++GO:0001996///positive regulation of heart rate by epinephrine-norepinephrine+++GO:0001997///positive regulation of the force of heart contraction by epinephrine-norepinephrine+++GO:0006937///regulation of muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0007512///adult heart development+++GO:0007626///locomotory behavior+++GO:0008217///regulation of blood pressure+++GO:0008542///visual learning+++GO:0009725///response to hormone+++GO:0010259///multicellular organism aging+++GO:0019229///regulation of vasoconstriction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035265///organ growth+++GO:0042593///glucose homeostasis+++GO:0043278///response to morphine+++GO:0043410///positive regulation of MAPK cascade+++GO:0045818///negative regulation of glycogen catabolic process+++GO:0045819///positive regulation of glycogen catabolic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0048148///behavioral response to cocaine+++GO:0048545///response to steroid hormone+++GO:0055117///regulation of cardiac muscle contraction+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway 115486031 115486031 'Gm51425' mRNA 209.91 251.68 193.32 3.96 4.66 3.85 2.5 2.28 3.43 4.156666667 2.736666667 152.83 136.97 203.84 218.3033333 164.5466667 0.055133446 -0.419399156 115486479 115486479 'Gm51460' mRNA 14.66 4 5 0.62 0.17 0.22 0.17 0.09 0.38 0.336666667 0.213333333 4.74 2.32 9.99 7.886666667 5.683333333 0.64411333 -0.622142186 115486481 115486481 'Gm45337' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005882///intermediate filament+++GO:0045095///keratin filament 115486489 115486489 'Gm51464' mRNA 2.54 1 1 0.06 0.02 0.03 0.08 0.09 0 0.036666667 0.056666667 4 4 0 1.513333333 2.666666667 0.675676317 0.98994457 115486510 115486510 'Gm45095' mRNA 80 81 86 0.64 0.64 0.73 0.75 0.6 0.68 0.67 0.676666667 108.34 85 95.11 82.33333333 96.15 0.523084061 0.206208216 115486519 115486519 'LOC115486519' mRNA 1 0 4.03 0.01 0 0.06 0.02 0.02 0.02 0.023333333 0.02 2 2 2 1.676666667 2 0.932161783 0.208190975 115486524 115486524 'Gm51483' mRNA 5 4 10.12 0.78 0.63 1.68 0.88 0.43 1 1.03 0.77 6.39 3 7 6.373333333 5.463333333 0.851450316 -0.281719018 115486880 115486880 'LOC115486880' mRNA 103.3 74.98 64.13 5.5 3.94 3.62 1.6 1.39 1.39 4.353333333 1.46 34.49 29.18 29.07 80.80333333 30.91333333 7.44E-05 -1.397193794 115486882 115486882 'Gm45750' mRNA 0 0 1 0 0 0.27 0 0.23 0.23 0.09 0.153333333 0 1 1 0.333333333 0.666666667 0.863090843 0.898087804 115486883 115486883 'Gm8940' mRNA 1.98 3 0.45 0.38 0.58 0.09 0 0.18 0.36 0.35 0.18 0 1 2 1.81 1 0.901199684 -0.380576882 115486932 115486932 'Gm51573' mRNA 1 1 0 0.02 0.02 0 0 0.06 0 0.013333333 0.02 0 3 0 0.666666667 1 0.866783358 0.624613079 115486940 115486940 'Gm51579' mRNA 66.2 65.73 76 1.7 1.67 2.08 1.23 1.05 1.18 1.816666667 1.153333333 55 46 51 69.31 50.66666667 0.191985086 -0.462327662 115486964 115486964 'Gm51590' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 115486965 115486965 'Gm51591' mRNA 0 1 0 0 0.02 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 115487111 115487111 'Gm29667' mRNA 60.89 70.03 59.56 0.32 0.36 0.33 0.27 0.35 0.32 0.336666667 0.313333333 58.85 74.89 68.65 63.49333333 67.46333333 0.863090843 0.073667572 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway+++05010///Alzheimer disease+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05415///Diabetic cardiomyopathy 115487164 115487164 'Gm1113' mRNA 22036 22948 21469 495.66 508.07 512.19 23.79 22.84 23.33 505.3066667 23.32 1210 1142 1155 22151 1169 0 -4.25585564 GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0050839///cell adhesion molecule binding GO:0098609///cell-cell adhesion 115487184 115487184 'Tma7-ps' mRNA 43.37 29.66 33.31 8.47 5.81 6.91 9.2 7.69 9.94 7.063333333 8.943333333 53.47 43.34 55.5 35.44666667 50.77 0.234684507 0.511369882 115487193 115487193 'Gm51691' mRNA 104.52 90.94 119.67 0.34 0.29 0.42 0.22 0.16 0.23 0.35 0.203333333 76.71 54.39 78.2 105.0433333 69.76666667 0.043326234 -0.609001252 115487351 115487351 'Gm39743' mRNA 85.24 57.87 75.76 2.21 1.48 2.08 1.68 1.73 1.67 1.923333333 1.693333333 74.72 75.24 71.78 72.95666667 73.91333333 0.996322951 0.005388354 115487375 115487375 'Gm48826' mRNA 0 0 2 0 0 0.06 0.11 0 0 0.02 0.036666667 5 0 0 0.666666667 1.666666667 0.748737812 1.220931445 115487405 115487405 'Gm46234' mRNA 1 0 0 1.12 0 0 1.04 0 0 0.373333333 0.346666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 115487435 115487435 'Gm51791' mRNA 2 0 0 0.28 0 0 0 0 0 0.093333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 115487436 115487436 'Gm51792' mRNA 29.98 13.24 14.27 0.46 0.2 0.23 0.13 0.29 0.35 0.296666667 0.256666667 9.87 20.75 24.86 19.16333333 18.49333333 0.924492862 -0.080073059 115487437 115487437 'Gm51793' mRNA 0 25.13 32.12 0 0.6 0.83 0 0.13 0.13 0.476666667 0.086666667 0 6.23 6.14 19.08333333 4.123333333 0.387526172 -2.267545903 115487466 115487466 'Gm48175' mRNA 1 2 0 0.28 0.56 0 0 0.51 0.51 0.28 0.34 0 2 2 1 1.333333333 0.881313794 0.448644199 115487746 115487746 'Gm51877' mRNA 21 22 18.55 0.73 0.75 0.68 0.37 0.46 0.61 0.72 0.48 12.1 15 19.68 20.51666667 15.59333333 0.564806797 -0.41368957 115487818 115487818 'Gm10840' mRNA 3.19 5 3 0.13 0.2 0.13 0.15 0.16 0 0.153333333 0.103333333 4.31 4.44 0 3.73 2.916666667 0.81656186 -0.467124322 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 115487957 115487957 'Gm51963' mRNA 8.89 9 10 1.52 1.54 1.81 0.45 0.77 0.94 1.623333333 0.72 3 5 6 9.296666667 4.666666667 0.377803938 -0.959533491 115487959 115487959 'Gm51965' mRNA 0 3 2 0 0.07 0.05 0.04 0 0 0.04 0.013333333 2 0 0 1.666666667 0.666666667 0.686252067 -1.359139846 115487996 115487996 'LOC115487996' mRNA 4 0 0 3.58 0 0 0 0 0 1.193333333 0 0 0 0 1.333333333 0 0.535994789 -2.842745962 04212///Longevity regulating pathway - worm 115488002 115488002 'LOC115488002' mRNA 39.12 51.89 47.28 0.73 0.95 0.93 0.41 0.48 0.33 0.87 0.406666667 25.09 28.74 19.61 46.09666667 24.48 0.035180314 -0.940326287 115488008 115488008 'Gm51999' mRNA 0 1.02 2.07 0 0.04 0.09 0.03 0.11 0.04 0.043333333 0.06 1 3.09 1.02 1.03 1.703333333 0.809491281 0.708444481 115488020 115488020 'Gm52009' mRNA 6 13 14 0.28 0.6 0.69 0.32 0.34 0.3 0.523333333 0.32 8 8.26 7.23 11 7.83 0.596262646 -0.540135701 115488029 115488029 'LOC115488029' mRNA 404.45 464.76 416.89 10.62 12.02 11.61 22.24 20.13 20.18 11.41666667 20.85 974.01 860.61 855.72 428.7 896.78 6.25E-23 1.054262507 115488119 115488119 'Gm47655' mRNA 11.34 11.31 4.76 0.77 0.76 0.34 0.75 0.55 0.98 0.623333333 0.76 12.77 9.08 15.98 9.136666667 12.61 0.637513132 0.471818574 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus 115488130 115488130 'LOC115488130' mRNA 193.4 217.98 226.65 2.86 3.17 3.56 2.2 2.19 2.33 3.196666667 2.24 171.24 166.5 175.57 212.6766667 171.1033333 0.103877038 -0.327112665 115488140 115488140 'Gm53057' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 115488157 115488157 'Gm52042' mRNA 137.58 133.66 151.59 3.81 3.64 4.45 8.8 6.87 8.84 3.966666667 8.17 365.55 278.8 355.65 140.9433333 333.3333333 5.40E-12 1.22889353 115488169 115488169 'Gm52051' mRNA 29 44 25.13 0.68 1.01 0.62 0.57 0.5 0.9 0.77 0.656666667 28 24 43 32.71 31.66666667 0.938100677 -0.048361169 115488170 115488170 'Rpl27a-ps4' mRNA 142.18 132.57 112.32 1.22 1.12 1.02 1.01 0.9 1.05 1.12 0.986666667 136.3 118.52 136.64 129.0233333 130.4866667 0.992070455 0.005477552 115488190 115488190 'Gm48350' mRNA 29.09 31.14 15.02 0.29 0.31 0.16 0.24 0.25 0.23 0.253333333 0.24 28.11 28.09 26.03 25.08333333 27.41 0.861332713 0.128754181 115488195 115488195 'Gm20379' mRNA 81 75.01 85 1.46 1.33 1.63 1.04 1.09 1.09 1.473333333 1.073333333 66 68 67 80.33666667 67 0.414676288 -0.27585162 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding GO:0006325///chromatin organization 115488203 115488203 'LOC115488203' mRNA 2 1 4 0.15 0.08 0.33 0.07 0 0.07 0.186666667 0.046666667 1 0 1 2.333333333 0.666666667 0.457143063 -1.851767451 115488204 115488204 'Gm45623' mRNA 2 4 1 0.03 0.06 0.02 0.14 0.14 0.24 0.036666667 0.173333333 11 11 19 2.333333333 13.66666667 0.012828977 2.552226518 GO:0016020///membrane+++GO:0016021///integral component of membrane 115488282 115488282 'Gm3512' mRNA 6.96 5.69 3 0.24 0.22 0.18 0.07 0.21 0.31 0.213333333 0.196666667 2 11 6 5.216666667 6.333333333 0.755090832 0.449563104 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 115488283 115488283 'LOC115488283' mRNA 1.5 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 0.5 0 0.863090843 -0.97353728 115488284 115488284 'Gm3752' mRNA 0 3.25 0 0 0.1 0 0.03 0 0 0.033333333 0.01 1.18 0 0 1.083333333 0.393333333 0.754495413 -1.44848948 115488350 115488350 'LOC115488350' mRNA 24.13 11.26 18.24 0.79 0.36 0.63 0.35 0.06 0.28 0.593333333 0.23 12.19 2.19 9.55 17.87666667 7.976666667 0.145490525 -1.228394585 115488359 115488359 'Gm52140' mRNA 5.03 7.06 1 0.15 0.21 0.03 0.09 0.11 0.03 0.13 0.076666667 3.4 4.06 1 4.363333333 2.82 0.704117668 -0.685512026 115488470 115488470 'LOC115488470' mRNA 373.27 341.07 284.97 1.59 1.43 1.29 1.17 1.08 1.24 1.436666667 1.163333333 314.94 284.06 323.08 333.1033333 307.36 0.49363594 -0.124312563 115488490 115488490 'LOC115488490' mRNA 25 29 16 1.29 1.48 0.88 0.45 0.32 0.23 1.216666667 0.333333333 10 7 5 23.33333333 7.333333333 0.01519709 -1.674428894 115488529 115488529 'LOC115488529' mRNA 4.16 7.21 5.15 0.15 0.26 0.2 0.26 0.37 0.13 0.203333333 0.253333333 8.33 11.54 4.14 5.506666667 8.003333333 0.684373866 0.516370337 115488536 115488536 'Gm52217' mRNA 30.93 29.4 16.19 0.77 0.72 0.43 0.28 0.14 0.12 0.64 0.18 12.71 6.11 5.55 25.50666667 8.123333333 0.012468816 -1.711209888 115488611 115488611 'Gm52229' mRNA 823.25 716.5 537.6 0.42 0.36 0.29 0.08 0.07 0.08 0.356666667 0.076666667 182.47 145.96 171.88 692.45 166.77 8.97E-41 -2.065897689 115488633 115488633 'Gm52241' mRNA 3 8 0 0.03 0.07 0 0.04 0.01 0.02 0.033333333 0.023333333 5 1 3 3.666666667 3 0.884948855 -0.275363105 115488671 115488671 'LOC115488671' mRNA 208.95 272.24 217.32 0.95 1.22 1.05 0.76 0.56 0.84 1.073333333 0.72 193 138.97 206.29 232.8366667 179.42 0.071637637 -0.387586676 115488765 115488765 'LOC115488765' mRNA 0 0 1.01 0 0 0.09 0 0 0 0.03 0 0 0 0 0.336666667 0 0.863090843 -0.97353728 115488789 115488789 'LOC115488789' mRNA 114.85 113.62 102.27 0.63 0.61 0.6 0.61 0.57 0.54 0.613333333 0.573333333 128.31 116.52 110.15 110.2466667 118.3266667 0.758641051 0.094584419 115488807 115488807 'Gm52310' mRNA 7.01 11.11 9.54 0.07 0.11 0.1 0.08 0.14 0.1 0.093333333 0.106666667 9.42 15.59 11.77 9.22 12.26 0.718811751 0.367247169 115489041 115489041 '9430078G10Rik' mRNA 7.43 6.49 2.07 0.11 0.1 0.03 0 0.03 0.03 0.08 0.02 0 2.17 2.4 5.33 1.523333333 0.266882513 -1.889806859 115489044 115489044 'LOC115489044' mRNA 11.21 9.66 7.68 0.72 0.61 0.52 0.23 0.36 0.28 0.616666667 0.29 4.21 6.23 4.8 9.516666667 5.08 0.381530071 -0.950945767 115489115 115489115 'LOC115489115' mRNA 1.01 0 0 0.2 0 0 0 0 0 0.066666667 0 0 0 0 0.336666667 0 0.863090843 -0.97353728 115489144 115489144 'Gm52451' mRNA 0 0 2 0 0 0.15 0 0 0 0.05 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 115489150 115489150 'Gm14681' mRNA 0 1.89 0 0 0.26 0 0.21 0.33 0 0.086666667 0.18 1.72 2.68 0 0.63 1.466666667 0.731322811 1.474625849 115489290 115489290 'Gm21828' mRNA 0 0 0.5 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.166666667 0 115489304 115489304 'Gm52481' mRNA 157 130 82 4.39 3.58 2.43 3.19 3.46 2.56 3.466666667 3.07 131 139 102 123 124 0.983614893 0.0098341 115489417 115489417 'LOC115489417' mRNA 15501.11 15322.22 13990.2 67.83 65.8 65.01 35.45 31.34 34.89 66.21333333 33.89333333 9454.56 8153.6 9068.96 14937.84333 8892.373333 1.37E-43 -0.759935723 115489434 115489434 'Gm13194' mRNA 5 7 4 0.94 1.32 0.8 0.67 0.51 0.35 1.02 0.51 4.01 3 2 5.333333333 3.003333333 0.569794644 -0.836529419 03010///Ribosome+++05171///Coronavirus disease - COVID-19 115489454 115489454 'Gm52512' mRNA 246.42 274.11 212.21 6.91 7.57 6.31 5.57 4.39 5.74 6.93 5.233333333 228.36 175.57 227.92 244.2466667 210.6166667 0.264817229 -0.225958724 115489487 115489487 'Gm14200' mRNA 6.66 5.05 6.08 0.78 0.58 0.75 1.03 1.48 1.16 0.703333333 1.223333333 10.15 14.14 10.98 5.93 11.75666667 0.300416676 0.988589327 115489545 115489545 'LOC115489545' mRNA 18.32 14.66 27.79 0.69 0.54 1.1 0.19 0.45 0.25 0.776666667 0.296666667 5.7 13.33 7.35 20.25666667 8.793333333 0.097636888 -1.258194941 115489748 115489748 'LOC115489748' mRNA 13.61 4.54 2.05 1.05 0.35 0.17 0 0.55 0.23 0.523333333 0.26 0 7.96 3.31 6.733333333 3.756666667 0.579806745 -0.903496056 115489888 115489888 'Gm52666' mRNA 118.87 143.85 92.81 2.95 3.51 2.44 2.65 3.04 2.44 2.966666667 2.71 123.09 137.74 109.61 118.51 123.48 0.863090843 0.059762661 115489946 115489946 'Gm30191' mRNA 1709 1716 1690 166.16 167.02 176.62 19.16 24.48 23.28 169.9333333 22.30666667 221 268 261 1705 250 3.78E-157 -2.780878403 115489950 115489950 'Zfp988' mRNA 0 2.16 3 0 0.04 0.05 0.02 0 0 0.03 0.006666667 1.29 0 0 1.72 0.43 0.49207178 -2.254384269 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 115489970 115489970 'Gm12790' mRNA 0 0 2 0 0 0.06 0.02 0 0.02 0.02 0.013333333 1 0 1 0.666666667 0.666666667 0.990920981 -0.084165033 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 115489972 115489972 'Gm52720' mRNA 233.7 264.62 287.03 6.46 7.2 8.42 12.79 11.88 12.77 7.36 12.48 531.91 482.39 514.05 261.7833333 509.45 2.09E-11 0.946217125 115489981 115489981 'LOC115489981' mRNA 816.31 801.12 682.89 4.64 4.47 4.11 2.91 2.48 3.15 4.406666667 2.846666667 589.27 492.94 620.68 766.7733333 567.63 1.36E-04 -0.444409069 11549 11549 'Adra1a' mRNA 45.33 34.01 27.76 0.22 0.16 0.14 0.06 0.07 0.05 0.173333333 0.06 12.67 15.64 12 35.7 13.43666667 0.006775675 -1.446765314 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04970///Salivary secretion GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098691///dopaminergic synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004937///alpha1-adrenergic receptor activity+++GO:0046982///protein heterodimerization activity "GO:0001985///negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure+++GO:0001994///norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0001996///positive regulation of heart rate by epinephrine-norepinephrine+++GO:0001997///positive regulation of the force of heart contraction by epinephrine-norepinephrine+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006937///regulation of muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0007512///adult heart development+++GO:0007568///aging+++GO:0008217///regulation of blood pressure+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0010259///multicellular organism aging+++GO:0010460///positive regulation of heart rate+++GO:0010507///negative regulation of autophagy+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0019229///regulation of vasoconstriction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035265///organ growth+++GO:0042493///response to drug+++GO:0043410///positive regulation of MAPK cascade+++GO:0045760///positive regulation of action potential+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060073///micturition+++GO:0060402///calcium ion transport into cytosol+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0097195///pilomotor reflex+++GO:1903997///positive regulation of non-membrane spanning protein tyrosine kinase activity+++GO:2000300///regulation of synaptic vesicle exocytosis" 115490127 115490127 'Gm10461' mRNA 96.71 95.42 81.55 1.04 1.01 0.93 0.88 0.76 0.59 0.993333333 0.743333333 93.89 79.3 60.83 91.22666667 78.00666667 0.477382879 -0.240430387 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 115490161 115490161 'Gm52800' mRNA 670.03 740.95 581.89 12.43 13.53 11.45 8.65 7.98 8.6 12.47 8.41 536.61 483.54 516.28 664.29 512.1433333 9.07E-04 -0.383940724 115490169 115490169 'Gm52806' mRNA 9 9 7 0.14 0.14 0.12 0.11 0.08 0.1 0.133333333 0.096666667 8 6 7 8.333333333 7 0.831203155 -0.260981358 115490184 115490184 'Gm42427' mRNA 1142.66 1120.05 1164.8 26.31 25.39 28.45 29.81 28.93 30.11 26.71666667 29.61666667 1489 1411.17 1456.11 1142.503333 1452.093333 9.62E-05 0.332999446 115490191 115490191 'Gm52817' mRNA 219.7 176.12 166.04 1.01 0.79 0.81 0.54 0.44 0.57 0.87 0.516666667 135.36 107.06 139.64 187.2866667 127.3533333 0.009375746 -0.568930158 115490200 115490200 'LOC115490200' mRNA 249.77 238.42 287.39 3.64 3.41 4.44 2.09 2.51 2.46 3.83 2.353333333 165.21 193.77 188.16 258.5266667 182.38 0.006771463 -0.518393239 115490335 115490335 'Gm44180' mRNA 7.04 7.04 9.12 0.9 0.89 1.23 1.68 0.48 0.7 1.006666667 0.953333333 15.06 4.23 6.03 7.733333333 8.44 0.93957185 0.091677397 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus 115490369 115490369 'Gm52875' mRNA 1 2 3 0.04 0.08 0.12 0.07 0 0.04 0.08 0.036666667 2 0 1.23 2 1.076666667 0.695559642 -1.040102481 115490387 115490387 'Gm10209' mRNA 20 17 5.19 1.02 0.86 0.28 0.13 0.14 0.46 0.72 0.243333333 3 3 10 14.06333333 5.333333333 0.16071702 -1.380921552 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 11550 11550 'Adra1d' mRNA 11 13 0 0.23 0.27 0 0.02 0.04 0.02 0.166666667 0.026666667 1 2 1 8 1.333333333 0.10150787 -2.556803305 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04970///Salivary secretion GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098691///dopaminergic synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004937///alpha1-adrenergic receptor activity+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity "GO:0001985///negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure+++GO:0001986///negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure+++GO:0001994///norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0001996///positive regulation of heart rate by epinephrine-norepinephrine+++GO:0001997///positive regulation of the force of heart contraction by epinephrine-norepinephrine+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006937///regulation of muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0007512///adult heart development+++GO:0007568///aging+++GO:0008217///regulation of blood pressure+++GO:0009725///response to hormone+++GO:0010259///multicellular organism aging+++GO:0010460///positive regulation of heart rate+++GO:0010507///negative regulation of autophagy+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0019229///regulation of vasoconstriction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035265///organ growth+++GO:0042493///response to drug+++GO:0043410///positive regulation of MAPK cascade+++GO:0045760///positive regulation of action potential+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060073///micturition+++GO:0060402///calcium ion transport into cytosol+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0097195///pilomotor reflex+++GO:1903997///positive regulation of non-membrane spanning protein tyrosine kinase activity+++GO:2000300///regulation of synaptic vesicle exocytosis" 11551 11551 'Adra2a' mRNA 38 50 31 0.55 0.72 0.48 1.38 1.58 1.28 0.583333333 1.413333333 109 122 98 39.66666667 109.6666667 1.34E-06 1.4621917 04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0098691///dopaminergic synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004938///alpha2-adrenergic receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031696///alpha-2C adrenergic receptor binding+++GO:0031996///thioesterase binding+++GO:0032795///heterotrimeric G-protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051379///epinephrine binding+++GO:0051380///norepinephrine binding GO:0001819///positive regulation of cytokine production+++GO:0002526///acute inflammatory response+++GO:0006260///DNA replication+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0019229///regulation of vasoconstriction+++GO:0030168///platelet activation+++GO:0030335///positive regulation of cell migration+++GO:0032147///activation of protein kinase activity+++GO:0032148///activation of protein kinase B activity+++GO:0032870///cellular response to hormone stimulus+++GO:0035624///receptor transactivation+++GO:0042311///vasodilation+++GO:0042593///glucose homeostasis+++GO:0042596///fear response+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0046676///negative regulation of insulin secretion+++GO:0050955///thermoception+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070473///negative regulation of uterine smooth muscle contraction+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0071881///adenylate cyclase-inhibiting adrenergic receptor signaling pathway+++GO:0071882///phospholipase C-activating adrenergic receptor signaling pathway+++GO:0090303///positive regulation of wound healing+++GO:2000300///regulation of synaptic vesicle exocytosis 11552 11552 'Adra2b' mRNA 2 0 1 0.03 0 0.01 0.09 0 0 0.013333333 0.03 8 0 0 1 2.666666667 0.634073244 1.3675404 04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004938///alpha2-adrenergic receptor activity+++GO:0005515///protein binding+++GO:0051379///epinephrine binding GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0019229///regulation of vasoconstriction+++GO:0030168///platelet activation+++GO:0032148///activation of protein kinase B activity+++GO:0035624///receptor transactivation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045666///positive regulation of neuron differentiation+++GO:0045777///positive regulation of blood pressure+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway 11553 11553 'Adra2c' mRNA 20 17 16 0.34 0.29 0.29 0.21 0.11 0.09 0.306666667 0.136666667 14 7 6 17.66666667 9 0.195933894 -0.988950085 04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004938///alpha2-adrenergic receptor activity+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051379///epinephrine binding GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0019229///regulation of vasoconstriction+++GO:0030168///platelet activation+++GO:0032148///activation of protein kinase B activity+++GO:0035624///receptor transactivation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045666///positive regulation of neuron differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0051930///regulation of sensory perception of pain+++GO:0070473///negative regulation of uterine smooth muscle contraction+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway 11554 11554 'Adrb1' mRNA 8 3 3 0.14 0.05 0.06 0.14 0.24 0.08 0.083333333 0.153333333 9 15 5 4.666666667 9.666666667 0.349367624 1.049432014 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04540///Gap junction+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04970///Salivary secretion+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004940///beta1-adrenergic receptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0043176///amine binding+++GO:0046982///protein heterodimerization activity+++GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential "GO:0001996///positive regulation of heart rate by epinephrine-norepinephrine+++GO:0001997///positive regulation of the force of heart contraction by epinephrine-norepinephrine+++GO:0002024///diet induced thermogenesis+++GO:0002025///norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0003061///positive regulation of the force of heart contraction by norepinephrine+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0005980///glycogen catabolic process+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0007613///memory+++GO:0009409///response to cold+++GO:0010460///positive regulation of heart rate+++GO:0019233///sensory perception of pain+++GO:0031649///heat generation+++GO:0033365///protein localization to organelle+++GO:0035811///negative regulation of urine volume+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042060///wound healing+++GO:0042596///fear response+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0045823///positive regulation of heart contraction+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0046878///positive regulation of saliva secretion+++GO:0050873///brown fat cell differentiation+++GO:0051924///regulation of calcium ion transport+++GO:0055088///lipid homeostasis+++GO:0060080///inhibitory postsynaptic potential+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0106071///positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900135///positive regulation of renin secretion into blood stream+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:2001259///positive regulation of cation channel activity" 11555 11555 'Adrb2' mRNA 195 201 240 4.83 4.9 6.31 10.77 10.24 9.63 5.346666667 10.21333333 500 464 433 212 465.6666667 2.46E-13 1.11839801 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04970///Salivary secretion+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0042383///sarcolemma+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0098978///glutamatergic synapse GO:0001540///amyloid-beta binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004941///beta2-adrenergic receptor activity+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0015459///potassium channel regulator activity+++GO:0019899///enzyme binding+++GO:0031713///B2 bradykinin receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051380///norepinephrine binding+++GO:0051721///protein phosphatase 2A binding+++GO:0090722///receptor-receptor interaction "GO:0001993///regulation of systemic arterial blood pressure by norepinephrine-epinephrine+++GO:0002024///diet induced thermogenesis+++GO:0002025///norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0002028///regulation of sodium ion transport+++GO:0002032///desensitization of G protein-coupled receptor signaling pathway by arrestin+++GO:0002086///diaphragm contraction+++GO:0003059///positive regulation of the force of heart contraction by epinephrine+++GO:0006898///receptor-mediated endocytosis+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0008284///positive regulation of cell proliferation+++GO:0008306///associative learning+++GO:0009409///response to cold+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0010765///positive regulation of sodium ion transport+++GO:0016525///negative regulation of angiogenesis+++GO:0030279///negative regulation of ossification+++GO:0030501///positive regulation of bone mineralization+++GO:0031649///heat generation+++GO:0032781///positive regulation of ATPase activity+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035811///negative regulation of urine volume+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042060///wound healing+++GO:0042311///vasodilation+++GO:0043065///positive regulation of apoptotic process+++GO:0043268///positive regulation of potassium ion transport+++GO:0043410///positive regulation of MAPK cascade+++GO:0045453///bone resorption+++GO:0045823///positive regulation of heart contraction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0050728///negative regulation of inflammatory response+++GO:0050873///brown fat cell differentiation+++GO:0051924///regulation of calcium ion transport+++GO:0051930///regulation of sensory perception of pain+++GO:0060079///excitatory postsynaptic potential+++GO:0061885///positive regulation of mini excitatory postsynaptic potential+++GO:0071456///cellular response to hypoxia+++GO:0071869///response to catecholamine+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090331///negative regulation of platelet aggregation+++GO:0097746///regulation of blood vessel diameter+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901098///positive regulation of autophagosome maturation+++GO:1904504///positive regulation of lipophagy+++GO:1904646///cellular response to amyloid-beta+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000969///positive regulation of AMPA receptor activity" 11556 11556 'Adrb3' mRNA 1 0 0 0.02 0 0 0 0.06 0 0.006666667 0.02 0 3 0 0.333333333 1 0.748737812 1.492222257 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04714///Thermogenesis+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04970///Salivary secretion+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0004939///beta-adrenergic receptor activity+++GO:0015052///beta3-adrenergic receptor activity+++GO:0031699///beta-3 adrenergic receptor binding+++GO:0042803///protein homodimerization activity+++GO:0051379///epinephrine binding+++GO:0051380///norepinephrine binding GO:0002024///diet induced thermogenesis+++GO:0002025///norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007568///aging+++GO:0009409///response to cold+++GO:0031649///heat generation+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042755///eating behavior+++GO:0043410///positive regulation of MAPK cascade+++GO:0046677///response to antibiotic+++GO:0050873///brown fat cell differentiation+++GO:0071875///adrenergic receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis 11564 11564 'Adsl' mRNA 1062 1060.94 1103.84 15.51 15.24 17.1 15.48 14.05 15.26 15.95 14.93 1220.07 1081.79 1165.03 1075.593333 1155.63 0.410744524 0.08971528 "00230///Purine metabolism+++00250///Alanine, aspartate and glutamate metabolism+++01240///Biosynthesis of cofactors" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0070852///cell body fiber "GO:0003824///catalytic activity+++GO:0004018///N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity+++GO:0004056///argininosuccinate lyase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0070626///(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity" GO:0000050///urea cycle+++GO:0000053///argininosuccinate metabolic process+++GO:0001666///response to hypoxia+++GO:0001889///liver development+++GO:0006163///purine nucleotide metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006167///AMP biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006526///arginine biosynthetic process+++GO:0007584///response to nutrient+++GO:0007626///locomotory behavior+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009060///aerobic respiration+++GO:0009152///purine ribonucleotide biosynthetic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0009791///post-embryonic development+++GO:0014850///response to muscle activity+++GO:0019676///ammonia assimilation cycle+++GO:0042450///arginine biosynthetic process via ornithine+++GO:0042594///response to starvation+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0044209///AMP salvage+++GO:0097294///'de novo' XMP biosynthetic process 11565 11565 'Adssl1' mRNA 804 782 634 25.89 24.82 21.66 18.66 26.46 25.65 24.12333333 23.59 666 922 886 740 824.6666667 0.332667244 0.15202145 "00230///Purine metabolism+++00250///Alanine, aspartate and glutamate metabolism+++01240///Biosynthesis of cofactors" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0004019///adenylosuccinate synthase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0006163///purine nucleotide metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006167///AMP biosynthetic process+++GO:0006531///aspartate metabolic process+++GO:0006541///glutamine metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0014074///response to purine-containing compound+++GO:0014850///response to muscle activity+++GO:0035690///cellular response to drug+++GO:0042594///response to starvation+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0044209///AMP salvage+++GO:0046040///IMP metabolic process+++GO:0060359///response to ammonium ion+++GO:0071257///cellular response to electrical stimulus 11566 11566 'Adss' mRNA 1176 1186 1125 25.62 25.44 26 23.92 23.14 25.72 25.68666667 24.26 1263 1193 1315 1162.333333 1257 0.292817957 0.101401618 "00230///Purine metabolism+++00250///Alanine, aspartate and glutamate metabolism+++01240///Biosynthesis of cofactors" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004019///adenylosuccinate synthase activity+++GO:0005525///GTP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006164///purine nucleotide biosynthetic process+++GO:0006167///AMP biosynthetic process+++GO:0006531///aspartate metabolic process+++GO:0014074///response to purine-containing compound+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0044209///AMP salvage+++GO:0046040///IMP metabolic process+++GO:0060359///response to ammonium ion+++GO:0071257///cellular response to electrical stimulus 11567 11567 'Avil' mRNA 23 22 21 0.32 0.32 0.34 0.35 0.57 0.36 0.326666667 0.426666667 29 39 27 22 31.66666667 0.347118055 0.516612594 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043005///neuron projection "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding+++GO:0071933///Arp2/3 complex binding" GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007399///nervous system development+++GO:0008154///actin polymerization or depolymerization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010976///positive regulation of neuron projection development+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping+++GO:0060271///cilium assembly+++GO:1900480///regulation of diacylglycerol biosynthetic process 11568 11568 'Aebp1' mRNA 2981 3060 2727 39.23 39.63 38.21 90.78 81.61 90.02 39.02333333 87.47 7922 6944 7610 2922.666667 7492 1.14E-119 1.346921181 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005516///calmodulin binding+++GO:0005518///collagen binding+++GO:0008270///zinc ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016485///protein processing+++GO:1904026///regulation of collagen fibril organization" 11569 11569 'Aebp2' mRNA 344 305 339 3.21 2.78 3.32 4.01 3.09 4.09 3.103333333 3.73 491 383 488 329.3333333 454 0.002970343 0.447792687 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035098///ESC/E(Z) complex "GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 11593 11593 'Aga' mRNA 654 649 597 27.55 26.97 27.09 38.17 34.9 38.46 27.20333333 37.17666667 982 869 939 633.3333333 930 1.71E-08 0.542831637 00511///Other glycan degradation+++04142///Lysosome GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum GO:0003948///N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0043621///protein self-association GO:0006508///proteolysis+++GO:0006517///protein deglycosylation 11595 11595 'Acan' mRNA 173 221 171 1.2 1.5 1.26 0.78 0.79 0.74 1.32 0.77 129 129 119 188.3333333 125.6666667 0.004793377 -0.592445879 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0072534///perineuronal net+++GO:0098966///perisynaptic extracellular matrix+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005540///hyaluronic acid binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0002063///chondrocyte development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0030166///proteoglycan biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0030336///negative regulation of cell migration 11596 11596 'Ager' mRNA 228 283 262 9.93 12.2 12.1 12.48 14.01 14.08 11.41 13.52333333 329 361 358 257.6666667 349.3333333 0.008022169 0.427791677 04613///Neutrophil extracellular trap formation+++04933///AGE-RAGE signaling pathway in diabetic complications+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0001650///fibrillar center+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0044548///S100 protein binding+++GO:0044877///protein-containing complex binding+++GO:0070379///high mobility group box 1 binding+++GO:1904599///advanced glycation end-product binding "GO:0001666///response to hypoxia+++GO:0001774///microglial cell activation+++GO:0001914///regulation of T cell mediated cytotoxicity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006954///inflammatory response+++GO:0007162///negative regulation of cell adhesion+++GO:0007259///JAK-STAT cascade+++GO:0007611///learning or memory+++GO:0010255///glucose mediated signaling pathway+++GO:0010508///positive regulation of autophagy+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010763///positive regulation of fibroblast migration+++GO:0014002///astrocyte development+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0023056///positive regulation of signaling+++GO:0023057///negative regulation of signaling+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0031175///neuron projection development+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045056///transcytosis+++GO:0046330///positive regulation of JNK cascade+++GO:0048143///astrocyte activation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050930///induction of positive chemotaxis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051101///regulation of DNA binding+++GO:0055074///calcium ion homeostasis+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0072657///protein localization to membrane+++GO:0090647///modulation of age-related behavioral decline+++GO:0150003///regulation of spontaneous synaptic transmission+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900453///negative regulation of long-term synaptic depression+++GO:1900744///regulation of p38MAPK cascade+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1901216///positive regulation of neuron death+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903523///negative regulation of blood circulation+++GO:1904472///positive regulation of endothelin secretion+++GO:1904597///negative regulation of connective tissue replacement involved in inflammatory response wound healing+++GO:1904604///negative regulation of advanced glycation end-product receptor activity+++GO:1904605///positive regulation of advanced glycation end-product receptor activity+++GO:1904645///response to amyloid-beta+++GO:1904646///cellular response to amyloid-beta+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000439///positive regulation of monocyte extravasation+++GO:2000514///regulation of CD4-positive, alpha-beta T cell activation+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process+++GO:2001200///positive regulation of dendritic cell differentiation" 11600 11600 'Angpt1' mRNA 34 17 25 0.43 0.21 0.33 0.22 0.28 0.34 0.323333333 0.28 20 25 30 25.33333333 25 0.967557881 -0.030653388 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002040///sprouting angiogenesis+++GO:0002092///positive regulation of receptor internalization+++GO:0002719///negative regulation of cytokine production involved in immune response+++GO:0003160///endocardium morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030210///heparin biosynthetic process+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031589///cell-substrate adhesion+++GO:0032680///regulation of tumor necrosis factor production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034394///protein localization to cell surface+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0043116///negative regulation of vascular permeability+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043393///regulation of protein binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045785///positive regulation of cell adhesion+++GO:0048014///Tie signaling pathway+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072012///glomerulus vasculature development+++GO:1905605///positive regulation of maintenance of permeability of blood-brain barrier+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000446///regulation of macrophage migration inhibitory factor signaling pathway 11601 11601 'Angpt2' mRNA 260 204 255 3.97 3.06 4.13 5.12 4.64 5.42 3.72 5.06 386 342 396 239.6666667 374.6666667 1.22E-04 0.628893192 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0062023///collagen-containing extracellular matrix GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005102///signaling receptor binding+++GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0042277///peptide binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048019///receptor antagonist activity GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001878///response to yeast+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001974///blood vessel remodeling+++GO:0003300///cardiac muscle hypertrophy+++GO:0006651///diacylglycerol biosynthetic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007492///endoderm development+++GO:0009303///rRNA transcription+++GO:0009314///response to radiation+++GO:0009612///response to mechanical stimulus+++GO:0009725///response to hormone+++GO:0009749///response to glucose+++GO:0010467///gene expression+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0031100///animal organ regeneration+++GO:0032148///activation of protein kinase B activity+++GO:0032431///activation of phospholipase A2 activity+++GO:0042327///positive regulation of phosphorylation+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045087///innate immune response+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0048014///Tie signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050928///negative regulation of positive chemotaxis+++GO:0060135///maternal process involved in female pregnancy+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071333///cellular response to glucose stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0072012///glomerulus vasculature development+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:2000272///negative regulation of signaling receptor activity 11603 11603 'Agrn' mRNA 2429 2483 1970 17.62 17.78 15.56 20.51 22.26 22.07 16.98666667 21.61333333 3209 3399 3399 2294 3335.666667 1.72E-12 0.533472884 04512///ECM-receptor interaction GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042383///sarcolemma+++GO:0043083///synaptic cleft+++GO:0044295///axonal growth cone+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0098978///glutamatergic synapse GO:0002162///dystroglycan binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030548///acetylcholine receptor regulator activity+++GO:0033691///sialic acid binding+++GO:0035374///chondroitin sulfate binding+++GO:0036122///BMP binding+++GO:0042030///ATPase inhibitor activity+++GO:0043236///laminin binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0044325///ion channel binding+++GO:0050431///transforming growth factor beta binding GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007009///plasma membrane organization+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0007416///synapse assembly+++GO:0007528///neuromuscular junction development+++GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0030154///cell differentiation+++GO:0032092///positive regulation of protein binding+++GO:0043086///negative regulation of catalytic activity+++GO:0043087///regulation of GTPase activity+++GO:0043113///receptor clustering+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045213///neurotransmitter receptor metabolic process+++GO:0045887///positive regulation of synaptic growth at neuromuscular junction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050807///regulation of synapse organization+++GO:0051491///positive regulation of filopodium assembly+++GO:0055117///regulation of cardiac muscle contraction+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:1902667///regulation of axon guidance+++GO:1903277///negative regulation of sodium ion export across plasma membrane+++GO:1903407///negative regulation of sodium:potassium-exchanging ATPase activity+++GO:2000541///positive regulation of protein geranylgeranylation 11604 11604 'Agrp' mRNA 5 5 2 0.44 0.44 0.23 0.1 0.29 0.5 0.37 0.296666667 1 3 5 4 3 0.828065242 -0.405068915 04920///Adipocytokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0043025///neuronal cell body GO:0005102///signaling receptor binding+++GO:0005184///neuropeptide hormone activity+++GO:0031779///melanocortin receptor binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0070996///type 1 melanocortin receptor binding GO:0007218///neuropeptide signaling pathway+++GO:0007623///circadian rhythm+++GO:0008343///adult feeding behavior+++GO:0009755///hormone-mediated signaling pathway+++GO:0032868///response to insulin+++GO:0042755///eating behavior+++GO:0048571///long-day photoperiodism+++GO:0060135///maternal process involved in female pregnancy+++GO:0060259///regulation of feeding behavior+++GO:2000253///positive regulation of feeding behavior 11605 11605 'Gla' mRNA 441 428 434 7.98 7.62 8.33 20.27 20.83 20.96 7.976666667 20.68666667 1288 1293 1290 434.3333333 1290.333333 8.51E-62 1.558874374 00052///Galactose metabolism+++00561///Glycerolipid metabolism+++00600///Sphingolipid metabolism+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004557///alpha-galactosidase activity+++GO:0005102///signaling receptor binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016936///galactoside binding+++GO:0017041///galactosylgalactosylglucosylceramidase activity+++GO:0042803///protein homodimerization activity+++GO:0052692///raffinose alpha-galactosidase activity" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0016139///glycoside catabolic process+++GO:0030282///bone mineralization+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0046477///glycosylceramide catabolic process+++GO:0046479///glycosphingolipid catabolic process+++GO:0051001///negative regulation of nitric-oxide synthase activity 11606 11606 'Agt' mRNA 1016 1012 1008 31.78 31.17 33.4 25.23 26.07 25.26 32.11666667 25.52 927 935 899 1012 920.3333333 0.13572592 -0.149201956 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04614///Renin-angiotensin system+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++05200///Pathways in cancer+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005179///hormone activity+++GO:0017080///sodium channel regulator activity+++GO:0031702///type 1 angiotensin receptor binding+++GO:0031703///type 2 angiotensin receptor binding+++GO:0048018///receptor ligand activity "GO:0000187///activation of MAPK activity+++GO:0001543///ovarian follicle rupture+++GO:0001568///blood vessel development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001822///kidney development+++GO:0001991///regulation of systemic arterial blood pressure by circulatory renin-angiotensin+++GO:0001998///angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0001999///renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure+++GO:0002018///renin-angiotensin regulation of aldosterone production+++GO:0002019///regulation of renal output by angiotensin+++GO:0002027///regulation of heart rate+++GO:0002035///brain renin-angiotensin system+++GO:0003014///renal system process+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0003081///regulation of systemic arterial blood pressure by renin-angiotensin+++GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0006606///protein import into nucleus+++GO:0006883///cellular sodium ion homeostasis+++GO:0007160///cell-matrix adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0007588///excretion+++GO:0008065///establishment of blood-nerve barrier+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008306///associative learning+++GO:0009409///response to cold+++GO:0009651///response to salt stress+++GO:0010468///regulation of gene expression+++GO:0010536///positive regulation of activation of Janus kinase activity+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0014061///regulation of norepinephrine secretion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014824///artery smooth muscle contraction+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0030308///negative regulation of cell growth+++GO:0030432///peristalsis+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032355///response to estradiol+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034104///negative regulation of tissue remodeling+++GO:0035106///operant conditioning+++GO:0035813///regulation of renal sodium excretion+++GO:0035815///positive regulation of renal sodium excretion+++GO:0038166///angiotensin-activated signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042310///vasoconstriction+++GO:0042311///vasodilation+++GO:0042445///hormone metabolic process+++GO:0042756///drinking behavior+++GO:0042981///regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045777///positive regulation of blood pressure+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046622///positive regulation of organ growth+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0048143///astrocyte activation+++GO:0048144///fibroblast proliferation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048659///smooth muscle cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051145///smooth muscle cell differentiation+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0051403///stress-activated MAPK cascade+++GO:0051924///regulation of calcium ion transport+++GO:0051969///regulation of transmission of nerve impulse+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070471///uterine smooth muscle contraction+++GO:0071260///cellular response to mechanical stimulus+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1900020///positive regulation of protein kinase C activity+++GO:1901201///regulation of extracellular matrix assembly+++GO:1902632///positive regulation of membrane hyperpolarization+++GO:1903598///positive regulation of gap junction assembly+++GO:1903779///regulation of cardiac conduction+++GO:1904385///cellular response to angiotensin+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1905010///positive regulation of L-lysine import across plasma membrane+++GO:1905589///positive regulation of L-arginine import across plasma membrane+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 11607 11607 'Agtr1a' mRNA 4 4 5 0.1 0.11 0.14 0.17 0.1 0.29 0.116666667 0.186666667 7 4 12 4.333333333 7.666666667 0.513355324 0.805463947 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04614///Renin-angiotensin system+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031968///organelle outer membrane+++GO:0055037///recycling endosome GO:0001596///angiotensin type I receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004945///angiotensin type II receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031711///bradykinin receptor binding+++GO:0031748///D1 dopamine receptor binding+++GO:0046982///protein heterodimerization activity GO:0001568///blood vessel development+++GO:0001819///positive regulation of cytokine production+++GO:0001822///kidney development+++GO:0001921///positive regulation of receptor recycling+++GO:0001991///regulation of systemic arterial blood pressure by circulatory renin-angiotensin+++GO:0002001///renin secretion into blood stream+++GO:0002018///renin-angiotensin regulation of aldosterone production+++GO:0002019///regulation of renal output by angiotensin+++GO:0002035///brain renin-angiotensin system+++GO:0006885///regulation of pH+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007266///Rho protein signal transduction+++GO:0007507///heart development+++GO:0007568///aging+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0009651///response to salt stress+++GO:0010259///multicellular organism aging+++GO:0010873///positive regulation of cholesterol esterification+++GO:0014823///response to activity+++GO:0019229///regulation of vasoconstriction+++GO:0019722///calcium-mediated signaling+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032430///positive regulation of phospholipase A2 activity+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034391///regulation of smooth muscle cell apoptotic process+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042310///vasoconstriction+++GO:0042416///dopamine biosynthetic process+++GO:0042756///drinking behavior+++GO:0042976///activation of Janus kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045766///positive regulation of angiogenesis+++GO:0045777///positive regulation of blood pressure+++GO:0046718///viral entry into host cell+++GO:0051412///response to corticosterone+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060326///cell chemotaxis+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0086097///phospholipase C-activating angiotensin-activated signaling pathway+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:1990776///response to angiotensin 11608 11608 'Agtr1b' mRNA 0 1 0 0 0.03 0 0.07 0.09 0.09 0.01 0.083333333 3 4 4 0.333333333 3.666666667 0.12672326 3.346404351 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04614///Renin-angiotensin system+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001596///angiotensin type I receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004945///angiotensin type II receptor activity+++GO:0031711///bradykinin receptor binding+++GO:0046982///protein heterodimerization activity GO:0001568///blood vessel development+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0001991///regulation of systemic arterial blood pressure by circulatory renin-angiotensin+++GO:0002035///brain renin-angiotensin system+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007266///Rho protein signal transduction+++GO:0007584///response to nutrient+++GO:0008217///regulation of blood pressure+++GO:0009651///response to salt stress+++GO:0010259///multicellular organism aging+++GO:0010873///positive regulation of cholesterol esterification+++GO:0019229///regulation of vasoconstriction+++GO:0019722///calcium-mediated signaling+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032430///positive regulation of phospholipase A2 activity+++GO:0035094///response to nicotine+++GO:0035902///response to immobilization stress+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042493///response to drug+++GO:0042756///drinking behavior+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045777///positive regulation of blood pressure+++GO:0046718///viral entry into host cell+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060326///cell chemotaxis+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0086097///phospholipase C-activating angiotensin-activated signaling pathway+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1990776///response to angiotensin 11609 11609 'Agtr2' mRNA 5 3 7 0.1 0.06 0.14 0.62 0.44 0.16 0.1 0.406666667 37 26 9 5 24 0.004996298 2.235063977 04080///Neuroactive ligand-receptor interaction+++04261///Adrenergic signaling in cardiomyocytes+++04614///Renin-angiotensin system GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004930///G protein-coupled receptor activity+++GO:0004945///angiotensin type II receptor activity+++GO:0008134///transcription factor binding "GO:0001819///positive regulation of cytokine production+++GO:0001822///kidney development+++GO:0001991///regulation of systemic arterial blood pressure by circulatory renin-angiotensin+++GO:0002018///renin-angiotensin regulation of aldosterone production+++GO:0002033///angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0002035///brain renin-angiotensin system+++GO:0006883///cellular sodium ion homeostasis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0008284///positive regulation of cell proliferation+++GO:0010243///response to organonitrogen compound+++GO:0010459///negative regulation of heart rate+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0021695///cerebellar cortex development+++GO:0032304///negative regulation of icosanoid secretion+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035556///intracellular signal transduction+++GO:0035566///regulation of metanephros size+++GO:0035640///exploration behavior+++GO:0035815///positive regulation of renal sodium excretion+++GO:0035932///aldosterone secretion+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042306///regulation of protein import into nucleus+++GO:0042311///vasodilation+++GO:0042416///dopamine biosynthetic process+++GO:0042981///regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0060993///kidney morphogenesis+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0072300///positive regulation of metanephric glomerulus development+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0097746///regulation of blood vessel diameter+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 11610 11610 'Agtrap' mRNA 2759 2673 2456 36.96 35.21 34.9 31.6 29.61 29.19 35.69 30.13333333 2715 2486 2429 2629.333333 2543.333333 0.470941216 -0.059119332 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0004945///angiotensin type II receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001666///response to hypoxia+++GO:0008217///regulation of blood pressure+++GO:0038166///angiotensin-activated signaling pathway 11614 11614 'Nr0b1' mRNA 0 1 0 0 0.03 0 0.03 0.03 0 0.01 0.02 1 1 0 0.333333333 0.666666667 0.863090843 0.881251873 04927///Cortisol synthesis and secretion GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0034451///centriolar satellite+++GO:0042788///polysomal ribosome+++GO:0043231///intracellular membrane-bounded organelle GO:0003690///double-stranded DNA binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019904///protein domain specific binding+++GO:0032448///DNA hairpin binding+++GO:0035258///steroid hormone receptor binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0050682///AF-2 domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007530///sex determination+++GO:0008104///protein localization+++GO:0008406///gonad development+++GO:0008584///male gonad development+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0030154///cell differentiation+++GO:0030238///male sex determination+++GO:0030325///adrenal gland development+++GO:0033144///negative regulation of intracellular steroid hormone receptor signaling pathway+++GO:0033327///Leydig cell differentiation+++GO:0035902///response to immobilization stress+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060008///Sertoli cell differentiation" 11615 11615 'Gm4737' mRNA 458.88 447.81 397.19 12.42 11.94 11.41 18.66 18.02 17.69 11.92333333 18.12333333 792.63 747.15 727.38 434.6266667 755.72 1.26E-13 0.78912953 00270///Cysteine and methionine metabolism GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042470///melanosome+++GO:0043005///neuron projection GO:0004013///adenosylhomocysteinase activity+++GO:0005507///copper ion binding+++GO:0030554///adenyl nucleotide binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0051287///NAD binding GO:0002439///chronic inflammatory response to antigenic stimulus+++GO:0006730///one-carbon metabolic process+++GO:0007584///response to nutrient+++GO:0019510///S-adenosylhomocysteine catabolic process+++GO:0033353///S-adenosylmethionine cycle+++GO:0042745///circadian sleep/wake cycle 11622 11622 'Ahr' mRNA 469 441 291 4.54 4.21 3.01 3.28 3.22 3.47 3.92 3.323333333 385 374 400 400.3333333 386.3333333 0.806024789 -0.054628034 04659///Th17 cell differentiation+++04934///Cushing syndrome+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0034751///aryl hydrocarbon receptor complex+++GO:0034752///cytosolic aryl hydrocarbon receptor complex+++GO:0034753///nuclear aryl hydrocarbon receptor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0015643///toxic substance binding+++GO:0017025///TBP-class protein binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001541///ovarian follicle development+++GO:0001568///blood vessel development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001782///B cell homeostasis+++GO:0001889///liver development+++GO:0001922///B-1 B cell homeostasis+++GO:0001974///blood vessel remodeling+++GO:0002260///lymphocyte homeostasis+++GO:0002376///immune system process+++GO:0002819///regulation of adaptive immune response+++GO:0002841///negative regulation of T cell mediated immune response to tumor cell+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003243///circumferential growth involved in left ventricle morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006805///xenobiotic metabolic process+++GO:0007049///cell cycle+++GO:0008015///blood circulation+++GO:0008217///regulation of blood pressure+++GO:0009410///response to xenobiotic stimulus+++GO:0009636///response to toxic substance+++GO:0010468///regulation of gene expression+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0014070///response to organic cyclic compound+++GO:0019933///cAMP-mediated signaling+++GO:0030183///B cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0030850///prostate gland development+++GO:0030888///regulation of B cell proliferation+++GO:0032922///circadian regulation of gene expression+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0035162///embryonic hemopoiesis+++GO:0035166///post-embryonic hemopoiesis+++GO:0040010///positive regulation of growth rate+++GO:0043010///camera-type eye development+++GO:0043029///T cell homeostasis+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045793///positive regulation of cell size+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045906///negative regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048514///blood vessel morphogenesis+++GO:0048536///spleen development+++GO:0048608///reproductive structure development+++GO:0048732///gland development+++GO:0048745///smooth muscle tissue development+++GO:0060420///regulation of heart growth+++GO:0060547///negative regulation of necrotic cell death+++GO:0060841///venous blood vessel development+++GO:0060993///kidney morphogenesis+++GO:0061009///common bile duct development+++GO:0071320///cellular response to cAMP+++GO:0072102///glomerulus morphogenesis+++GO:0097746///regulation of blood vessel diameter+++GO:1903170///negative regulation of calcium ion transmembrane transport+++GO:1904322///cellular response to forskolin+++GO:1904613///cellular response to 2,3,7,8-tetrachlorodibenzodioxine+++GO:1904682///cellular response to 3-methylcholanthrene+++GO:2000279///negative regulation of DNA biosynthetic process" 11624 11624 'Ahrr' mRNA 3 4 6 0.04 0.05 0.08 0.09 0.21 0.06 0.056666667 0.12 9 20 4 4.333333333 11 0.220484022 1.32875802 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034751///aryl hydrocarbon receptor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004879///nuclear receptor activity+++GO:0046983///protein dimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006805///xenobiotic metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0030522///intracellular receptor signaling pathway+++GO:0033235///positive regulation of protein sumoylation+++GO:0045892///negative regulation of transcription, DNA-templated" 11625 11625 'Ahsg' mRNA 15 8 7 0.58 0.31 0.29 0.03 0.07 0.11 0.393333333 0.07 1 2 3 10 2 0.046826468 -2.322880657 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030294///receptor signaling protein tyrosine kinase inhibitor activity GO:0001503///ossification+++GO:0006953///acute-phase response+++GO:0008584///male gonad development+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030308///negative regulation of cell growth+++GO:0030502///negative regulation of bone mineralization+++GO:0045780///positive regulation of bone resorption+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050727///regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0065003///protein-containing complex assembly 11629 11629 'Aif1' mRNA 141 158 172 9.85 10.96 12.68 86 92.59 89.74 11.16333333 89.44333333 1404 1471 1419 157 1431.333333 4.20E-163 3.175674801 GO:0001726///ruffle+++GO:0001891///phagocytic cup+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding "GO:0001774///microglial cell activation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006911///phagocytosis, engulfment+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0014739///positive regulation of muscle hyperplasia+++GO:0016601///Rac protein signal transduction+++GO:0021549///cerebellum development+++GO:0030041///actin filament polymerization+++GO:0030046///parallel actin filament bundle assembly+++GO:0030335///positive regulation of cell migration+++GO:0031668///cellular response to extracellular stimulus+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032870///cellular response to hormone stimulus+++GO:0034097///response to cytokine+++GO:0034599///cellular response to oxidative stress+++GO:0042102///positive regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048678///response to axon injury+++GO:0050921///positive regulation of chemotaxis+++GO:0051017///actin filament bundle assembly+++GO:0051384///response to glucocorticoid+++GO:0051602///response to electrical stimulus+++GO:0051764///actin crosslink formation+++GO:0071315///cellular response to morphine+++GO:0071346///cellular response to interferon-gamma+++GO:0071447///cellular response to hydroperoxide+++GO:0071672///negative regulation of smooth muscle cell chemotaxis+++GO:0071673///positive regulation of smooth muscle cell chemotaxis+++GO:0071677///positive regulation of mononuclear cell migration+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:0097178///ruffle assembly+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2000406///positive regulation of T cell migration" 11630 11630 'Crybg1' mRNA 571 577 274 4.01 3.99 2.05 2.58 3.26 3.13 3.35 2.99 419 523 497 474 479.6666667 0.960903326 0.023733686 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0030246///carbohydrate binding GO:0008150///biological_process 11632 11632 'Aip' mRNA 1350.49 1400.1 1407.95 60.93 60.35 65.82 65.58 68.75 64.69 62.36666667 66.34 1696.86 1729.04 1626.79 1386.18 1684.23 0.001401099 0.268300407 04934///Cushing syndrome+++05207///Chemical carcinogenesis - receptor activation GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034751///aryl hydrocarbon receptor complex GO:0003712///transcription coregulator activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0036004///GAF domain binding+++GO:0051082///unfolded protein binding GO:0006626///protein targeting to mitochondrion+++GO:0006805///xenobiotic metabolic process+++GO:0010738///regulation of protein kinase A signaling+++GO:0022417///protein maturation by protein folding+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity 11634 11634 'Aire' mRNA 162 134 133 6.6 5.88 5.95 2.27 2.34 2.43 6.143333333 2.346666667 66 68 69 143 67.66666667 8.70E-06 -1.089902679 04120///Ubiquitin mediated proteolysis+++05340///Primary immunodeficiency GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0045182///translation regulator activity+++GO:0046872///metal ion binding" "GO:0002458///peripheral T cell tolerance induction+++GO:0002509///central tolerance induction to self antigen+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006417///regulation of translation+++GO:0006959///humoral immune response+++GO:0032722///positive regulation of chemokine production+++GO:0045060///negative thymic T cell selection+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097536///thymus epithelium morphogenesis+++GO:2000410///regulation of thymocyte migration" 11636 11636 'Ak1' mRNA 2751 2798 2819 75.57 75.74 82.21 68.89 69.48 64.06 77.84 67.47666667 2870 2818 2584 2789.333333 2757.333333 0.763426269 -0.02985984 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030017///sarcomere+++GO:0036126///sperm flagellum+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016776///phosphotransferase activity, phosphate group as acceptor+++GO:0019205///nucleobase-containing compound kinase activity" GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006172///ADP biosynthetic process+++GO:0007050///cell cycle arrest+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0016310///phosphorylation+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046103///inosine biosynthetic process+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 11637 11637 'Ak2' mRNA 876 962 874 29.52 32.16 31.09 59.07 57.41 61.34 30.92333333 59.27333333 2016 1909 2037 904 1987.333333 4.91E-48 1.125156518 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0036126///sperm flagellum+++GO:0097226///sperm mitochondrial sheath "GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016776///phosphotransferase activity, phosphate group as acceptor+++GO:0019205///nucleobase-containing compound kinase activity" GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006172///ADP biosynthetic process+++GO:0016310///phosphorylation+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046060///dATP metabolic process+++GO:0046940///nucleoside monophosphate phosphorylation 11639 11639 'Ak4' mRNA 489.97 478.17 394.5 3.76 3.62 3.24 1.7 1.72 1.95 3.54 1.79 250.73 240.58 273.63 454.2133333 254.98 1.51E-09 -0.843056003 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix "GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016776///phosphotransferase activity, phosphate group as acceptor+++GO:0019205///nucleobase-containing compound kinase activity+++GO:0042802///identical protein binding+++GO:0046899///nucleoside triphosphate adenylate kinase activity" GO:0001889///liver development+++GO:0002082///regulation of oxidative phosphorylation+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006172///ADP biosynthetic process+++GO:0006756///AMP phosphorylation+++GO:0007420///brain development+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0042493///response to drug+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046039///GTP metabolic process+++GO:0046041///ITP metabolic process+++GO:0046051///UTP metabolic process+++GO:0046060///dATP metabolic process+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0071456///cellular response to hypoxia+++GO:2001169///regulation of ATP biosynthetic process 11640 11640 'Akap1' mRNA 423 452 207 6.25 6.51 3.21 3.44 4.11 4.32 5.323333333 3.956666667 275 321 334 360.6666667 310 0.404380462 -0.213141121 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031594///neuromuscular junction+++GO:0045211///postsynaptic membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030346///protein phosphatase 2B binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0048487///beta-tubulin binding+++GO:0060090///molecular adaptor activity GO:0006915///apoptotic process+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0042308///negative regulation of protein import into nucleus 11647 11647 'Alpl' mRNA 91 101 99 2.01 2.22 2.37 1.83 2.78 1.91 2.2 2.173333333 93 139 95 97 109 0.64476352 0.158702441 00730///Thiamine metabolism+++00790///Folate biosynthesis+++01240///Biosynthesis of cofactors GO:0005615///extracellular space+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane+++GO:0031966///mitochondrial membrane+++GO:0065010///extracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004035///alkaline phosphatase activity+++GO:0005515///protein binding+++GO:0016462///pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0050187///phosphoamidase activity GO:0001958///endochondral ossification+++GO:0003006///developmental process involved in reproduction+++GO:0016311///dephosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0033280///response to vitamin D+++GO:0046677///response to antibiotic+++GO:0051384///response to glucocorticoid+++GO:0071407///cellular response to organic cyclic compound+++GO:0071529///cementum mineralization 11651 11651 'Akt1' mRNA 703 721 595 15.1 15.3 13.62 20.48 21.77 23.06 14.67333333 21.77 1094 1135 1195 673 1141.333333 2.90E-15 0.754020249 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0036064///ciliary basal body "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0032794///GTPase activating protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0051721///protein phosphatase 2A binding+++GO:0071889///14-3-3 protein binding+++GO:0099104///potassium channel activator activity" "GO:0001649///osteoblast differentiation+++GO:0001893///maternal placenta development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002931///response to ischemia+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006606///protein import into nucleus+++GO:0006915///apoptotic process+++GO:0006924///activation-induced cell death of T cells+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007399///nervous system development+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008637///apoptotic mitochondrial changes+++GO:0008643///carbohydrate transport+++GO:0009408///response to heat+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010467///gene expression+++GO:0010507///negative regulation of autophagy+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010748///negative regulation of plasma membrane long-chain fatty acid transport+++GO:0010763///positive regulation of fibroblast migration+++GO:0010765///positive regulation of sodium ion transport+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010975///regulation of neuron projection development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021510///spinal cord development+++GO:0030030///cell projection organization+++GO:0030163///protein catabolic process+++GO:0030212///hyaluronan metabolic process+++GO:0030307///positive regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031641///regulation of myelination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0032079///positive regulation of endodeoxyribonuclease activity+++GO:0032091///negative regulation of protein binding+++GO:0032094///response to food+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0032880///regulation of protein localization+++GO:0032929///negative regulation of superoxide anion generation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034405///response to fluid shear stress+++GO:0034614///cellular response to reactive oxygen species+++GO:0035556///intracellular signal transduction+++GO:0035655///interleukin-18-mediated signaling pathway+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036294///cellular response to decreased oxygen levels+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042593///glucose homeostasis+++GO:0042640///anagen+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045792///negative regulation of cell size+++GO:0045861///negative regulation of proteolysis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0046329///negative regulation of JNK cascade+++GO:0046622///positive regulation of organ growth+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048266///behavioral response to pain+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051146///striated muscle cell differentiation+++GO:0060416///response to growth hormone+++GO:0060709///glycogen cell differentiation involved in embryonic placenta development+++GO:0060716///labyrinthine layer blood vessel development+++GO:0070141///response to UV-A+++GO:0070848///response to growth factor+++GO:0071260///cellular response to mechanical stimulus+++GO:0071276///cellular response to cadmium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0072656///maintenance of protein location in mitochondrion+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0097194///execution phase of apoptosis+++GO:0110099///negative regulation of calcium import into the mitochondrion+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901653///cellular response to peptide+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903715///regulation of aerobic respiration+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990418///response to insulin-like growth factor stimulus+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000402///negative regulation of lymphocyte migration+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 11652 11652 'Akt2' mRNA 6509 7019 6799 113.64 120.35 126.58 88.95 94.13 87.3 120.19 90.12666667 5814 5975 5544 6775.666667 5777.666667 2.28E-04 -0.242220916 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031982///vesicle+++GO:0032587///ruffle membrane+++GO:0032593///insulin-responsive compartment+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008643///carbohydrate transport+++GO:0009967///positive regulation of signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0010748///negative regulation of plasma membrane long-chain fatty acid transport+++GO:0010765///positive regulation of sodium ion transport+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0031340///positive regulation of vesicle fusion+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0033119///negative regulation of RNA splicing+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034504///protein localization to nucleus+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0050927///positive regulation of positive chemotaxis+++GO:0065002///intracellular protein transmembrane transport+++GO:0071407///cellular response to organic cyclic compound+++GO:0071486///cellular response to high light intensity+++GO:0072659///protein localization to plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0090630///activation of GTPase activity+++GO:0097473///retinal rod cell apoptotic process+++GO:2000147///positive regulation of cell motility 11655 11655 'Alas1' mRNA 1088 1077 1063 22.29 21.71 23.1 38.07 42.27 39.36 22.36666667 39.9 2139 2318 2140 1076 2199 8.13E-38 1.019920771 "00260///Glycine, serine and threonine metabolism+++00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0003870///5-aminolevulinate synthase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding" GO:0001666///response to hypoxia+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0009058///biosynthetic process+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0042541///hemoglobin biosynthetic process+++GO:0048821///erythrocyte development 11656 11656 'Alas2' mRNA 68.84 83.36 77 1.99 2.39 2.35 2.35 2.69 2.86 2.243333333 2.633333333 93.82 104.83 109 76.4 102.55 0.155517384 0.413556842 "00260///Glycine, serine and threonine metabolism+++00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0003824///catalytic activity+++GO:0003870///5-aminolevulinate synthase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding" GO:0001666///response to hypoxia+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0006879///cellular iron ion homeostasis+++GO:0009058///biosynthetic process+++GO:0030218///erythrocyte differentiation+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0042541///hemoglobin biosynthetic process+++GO:0048821///erythrocyte development 11658 11658 'Alcam' mRNA 1103 1064 936 11.68 11.08 10.51 11.76 10.56 11.29 11.09 11.20333333 1278 1122 1189 1034.333333 1196.333333 0.031594704 0.199510469 04514///Cell adhesion molecules GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0042101///T cell receptor complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0031290///retinal ganglion cell axon guidance+++GO:0048846///axon extension involved in axon guidance+++GO:1990138///neuron projection extension 116621581 116621581 'Derpc' mRNA 397.59 472.64 274.92 7.5 8.87 5.62 5.81 5.13 4.17 7.33 5.036666667 347.08 296.67 247.21 381.7166667 296.9866667 0.063009181 -0.36471378 GO:0005654///nucleoplasm 11666 11666 'Abcd1' mRNA 843.96 896.9 735 12.55 13.12 11.59 19.1 19.96 19.81 12.42 19.62333333 1477.8 1509 1484.94 825.2866667 1490.58 1.61E-23 0.84498658 02010///ABC transporters+++04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015607///fatty-acyl-CoA transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046982///protein heterodimerization activity+++GO:0047617///acyl-CoA hydrolase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0002082///regulation of oxidative phosphorylation+++GO:0006635///fatty acid beta-oxidation+++GO:0007031///peroxisome organization+++GO:0015910///peroxisomal long-chain fatty acid import+++GO:0015916///fatty-acyl-CoA transport+++GO:0030497///fatty acid elongation+++GO:0031998///regulation of fatty acid beta-oxidation+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0036113///very long-chain fatty-acyl-CoA catabolic process+++GO:0042758///long-chain fatty acid catabolic process+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0043217///myelin maintenance+++GO:0051900///regulation of mitochondrial depolarization+++GO:0055085///transmembrane transport+++GO:0055089///fatty acid homeostasis+++GO:0055092///sterol homeostasis+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1990535///neuron projection maintenance+++GO:2001280///positive regulation of unsaturated fatty acid biosynthetic process 11668 11668 'Aldh1a1' mRNA 6130 6470 6472 161.39 166.3 179.18 145.1 133.29 140.38 168.9566667 139.59 6142 5523 5776 6357.333333 5813.666667 0.036991225 -0.143114104 00830///Retinol metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm "GO:0001758///retinal dehydrogenase activity+++GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016918///retinal binding+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0019145///aminobutyraldehyde dehydrogenase activity+++GO:0042802///identical protein binding+++GO:0051287///NAD binding" GO:0001523///retinoid metabolic process+++GO:0001568///blood vessel development+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001936///regulation of endothelial cell proliferation+++GO:0001947///heart looping+++GO:0002072///optic cup morphogenesis involved in camera-type eye development+++GO:0002138///retinoic acid biosynthetic process+++GO:0003007///heart morphogenesis+++GO:0006979///response to oxidative stress+++GO:0007494///midgut development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009449///gamma-aminobutyric acid biosynthetic process+++GO:0009855///determination of bilateral symmetry+++GO:0009952///anterior/posterior pattern specification+++GO:0009954///proximal/distal pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0014032///neural crest cell development+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030392///fructosamine catabolic process+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0031016///pancreas development+++GO:0031076///embryonic camera-type eye development+++GO:0032355///response to estradiol+++GO:0033189///response to vitamin A+++GO:0034097///response to cytokine+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035799///ureter maturation+++GO:0036438///maintenance of lens transparency+++GO:0042493///response to drug+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042574///retinal metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0042905///9-cis-retinoic acid metabolic process+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0048048///embryonic eye morphogenesis+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048566///embryonic digestive tract development+++GO:0048738///cardiac muscle tissue development+++GO:0051289///protein homotetramerization+++GO:0060324///face development+++GO:0071300///cellular response to retinoic acid+++GO:0090242///retinoic acid receptor signaling pathway involved in somitogenesis+++GO:0110095///cellular detoxification of aldehyde+++GO:0120163///negative regulation of cold-induced thermogenesis 11669 11669 'Aldh2' mRNA 5841 6068 4865 118.4 117.94 102.5 120.4 118.59 125.94 112.9466667 121.6433333 7010 6726 7137 5591.333333 6957.666667 1.46E-06 0.307663434 "00010///Glycolysis / Gluconeogenesis+++00053///Ascorbate and aldarate metabolism+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++00770///Pantothenate and CoA biosynthesis+++00981///Insect hormone biosynthesis+++01240///Biosynthesis of cofactors+++04936///Alcoholic liver disease" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity+++GO:0051287///NAD binding+++GO:0070404///NADH binding" GO:0006068///ethanol catabolic process+++GO:0006117///acetaldehyde metabolic process+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0014070///response to organic cyclic compound+++GO:0043066///negative regulation of apoptotic process+++GO:0048149///behavioral response to ethanol+++GO:0050727///regulation of inflammatory response+++GO:0110095///cellular detoxification of aldehyde+++GO:2000377///regulation of reactive oxygen species metabolic process 11670 11670 'Aldh3a1' mRNA 199 162 176 7.26 5.82 6.84 11.01 12.81 13.27 6.64 12.36333333 349 394 404 179 382.3333333 1.94E-11 1.083939754 00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0001666///response to hypoxia+++GO:0006081///cellular aldehyde metabolic process+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0014070///response to organic cyclic compound+++GO:0042493///response to drug+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP 116701 116701 'Fgfrl1' mRNA 1147 1180 1276 24.96 25.29 29.54 20.64 20.03 21.19 26.59666667 20.62 1061 1010 1095 1201 1055.333333 0.052970768 -0.201393347 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0044291///cell-cell contact zone GO:0001571///non-tyrosine kinase fibroblast growth factor receptor activity+++GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0008201///heparin binding+++GO:0017134///fibroblast growth factor binding+++GO:0042802///identical protein binding GO:0001501///skeletal system development+++GO:0003179///heart valve morphogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0060412///ventricular septum morphogenesis+++GO:0060539///diaphragm development+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 11671 11671 'Aldh3a2' mRNA 1665 1890 1697 28.59 32.15 30.7 38.22 37.35 35.6 30.48 37.05666667 2543 2429 2302 1750.666667 2424.666667 8.00E-10 0.458359475 "00010///Glycolysis / Gluconeogenesis+++00053///Ascorbate and aldarate metabolism+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++00770///Pantothenate and CoA biosynthesis+++00981///Insect hormone biosynthesis+++01240///Biosynthesis of cofactors+++04936///Alcoholic liver disease" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0042803///protein homodimerization activity+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity+++GO:0046577///long-chain-alcohol oxidase activity+++GO:0050061///long-chain-aldehyde dehydrogenase activity+++GO:0052814///medium-chain-aldehyde dehydrogenase activity" GO:0000302///response to reactive oxygen species+++GO:0006081///cellular aldehyde metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006714///sesquiterpenoid metabolic process+++GO:0007417///central nervous system development+++GO:0007422///peripheral nervous system development+++GO:0008544///epidermis development+++GO:0033306///phytol metabolic process+++GO:0046292///formaldehyde metabolic process+++GO:0046458///hexadecanal metabolic process 116731 116731 'Pcdha1' mRNA 0 1.8 2.62 0 0.02 0.03 0 0 0 0.016666667 0 0 0 0 1.473333333 0 0.596502362 -2.487866303 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 116732 116732 'Tsga13' mRNA 1 2 1 0.01 0.06 0.07 0 0 0 0.046666667 0 0 0 0 1.333333333 0 0.437121753 -2.859116386 GO:0005575///cellular_component GO:0003674///molecular_function 116733 116733 'Vps4a' mRNA 1154 1329 1213 30.55 34.65 34.06 29.95 31.08 28.32 33.08666667 29.78333333 1301 1318 1191 1232 1270 0.798599342 0.032313674 04144///Endocytosis+++04217///Necroptosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005774///vacuolar membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0090543///Flemming body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding GO:0006622///protein targeting to lysosome+++GO:0006900///vesicle budding from membrane+++GO:0006997///nucleus organization+++GO:0007033///vacuole organization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0009838///abscission+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016197///endosomal transport+++GO:0019076///viral release from host cell+++GO:0032367///intracellular cholesterol transport+++GO:0032466///negative regulation of cytokinesis+++GO:0032880///regulation of protein localization+++GO:0034058///endosomal vesicle fusion+++GO:0036258///multivesicular body assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0044878///mitotic cytokinesis checkpoint+++GO:0046761///viral budding from plasma membrane+++GO:0048524///positive regulation of viral process+++GO:0051301///cell division+++GO:0061738///late endosomal microautophagy+++GO:0061952///midbody abscission+++GO:0072319///vesicle uncoating+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:1902188///positive regulation of viral release from host cell+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903543///positive regulation of exosomal secretion+++GO:1903774///positive regulation of viral budding via host ESCRT complex+++GO:1903902///positive regulation of viral life cycle 11674 11674 'Aldoa' mRNA 29780 29860 28873 1172.02 1160.94 1207.51 907.99 933.62 889.37 1180.156667 910.3266667 26369 26488 25011 29504.33333 25956 1.60E-04 -0.196730674 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway GO:0000792///heterochromatin+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0031674///I band+++GO:0032991///protein-containing complex+++GO:0035686///sperm fibrous sheath+++GO:0043209///myelin sheath+++GO:0061827///sperm head+++GO:0070062///extracellular exosome GO:0002020///protease binding+++GO:0003824///catalytic activity+++GO:0004332///fructose-bisphosphate aldolase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0070061///fructose binding "GO:0001666///response to hypoxia+++GO:0006000///fructose metabolic process+++GO:0006096///glycolytic process+++GO:0006754///ATP biosynthetic process+++GO:0006941///striated muscle contraction+++GO:0007339///binding of sperm to zona pellucida+++GO:0008360///regulation of cell shape+++GO:0009408///response to heat+++GO:0019242///methylglyoxal biosynthetic process+++GO:0030335///positive regulation of cell migration+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0032496///response to lipopolysaccharide+++GO:0035094///response to nicotine+++GO:0043627///response to estrogen+++GO:0046716///muscle cell cellular homeostasis+++GO:0051289///protein homotetramerization+++GO:0061615///glycolytic process through fructose-6-phosphate" 116748 116748 'Lsm10' mRNA 245 294 310 18.47 22.16 25.24 34.42 35.47 34.47 21.95666667 34.78666667 532 553 512 283 532.3333333 2.68E-10 0.897109868 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005683///U7 snRNP+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0071254///cytoplasmic U snRNP body GO:0003723///RNA binding+++GO:0017069///snRNA binding+++GO:0071208///histone pre-mRNA DCP binding+++GO:0071209///U7 snRNA binding GO:0006397///mRNA processing+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0008380///RNA splicing+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 11676 11676 'Aldoc' mRNA 9391 9673 9461 193.98 196.67 207.3 86.14 84.26 87.79 199.3166667 86.06333333 4797 4582 4734 9508.333333 4704.333333 2.20E-79 -1.027920973 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0099524///postsynaptic cytosol GO:0003824///catalytic activity+++GO:0004332///fructose-bisphosphate aldolase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding "GO:0006096///glycolytic process+++GO:0006915///apoptotic process+++GO:0007568///aging+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0030855///epithelial cell differentiation" 11677 11677 'Akr1b3' mRNA 1238 1329 1128 52.74 55.86 50.98 86.06 83.3 85.56 53.19333333 84.97333333 2320 2191 2231 1231.666667 2247.333333 1.72E-33 0.857731943 00040///Pentose and glucuronate interconversions+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00561///Glycerolipid metabolism+++00790///Folate biosynthesis GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032838///plasma membrane bounded cell projection cytoplasm+++GO:0033010///paranodal junction+++GO:0042629///mast cell granule+++GO:0043220///Schmidt-Lanterman incisure+++GO:0048471///perinuclear region of cytoplasm+++GO:0097454///Schwann cell microvillus "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0018505///cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity+++GO:0036130///prostaglandin H2 endoperoxidase reductase activity+++GO:0043795///glyceraldehyde oxidoreductase activity+++GO:0047655///allyl-alcohol dehydrogenase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0047956///glycerol dehydrogenase [NADP+] activity+++GO:0052650///NADP-retinol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0001894///tissue homeostasis+++GO:0002070///epithelial cell maturation+++GO:0003091///renal water homeostasis+++GO:0005996///monosaccharide metabolic process+++GO:0006061///sorbitol biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0009414///response to water deprivation+++GO:0010033///response to organic substance+++GO:0018931///naphthalene metabolic process+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0035809///regulation of urine volume+++GO:0042415///norepinephrine metabolic process+++GO:0042572///retinol metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0060135///maternal process involved in female pregnancy+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071475///cellular hyperosmotic salinity response+++GO:0072061///inner medullary collecting duct development+++GO:0072205///metanephric collecting duct development+++GO:0097066///response to thyroid hormone+++GO:0097238///cellular response to methylglyoxal+++GO:1901360///organic cyclic compound metabolic process+++GO:1901653///cellular response to peptide 116810 116810 'Foxn4' mRNA 31 18 23 0.52 0.33 0.4 0 0.03 0.03 0.416666667 0.02 0 2 2 24 1.333333333 3.09E-05 -4.178423946 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001947///heart looping+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008016///regulation of heart contraction+++GO:0010842///retina layer formation+++GO:0021514///ventral spinal cord interneuron differentiation+++GO:0030154///cell differentiation+++GO:0035881///amacrine cell differentiation+++GO:0036302///atrioventricular canal development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment+++GO:0060579///ventral spinal cord interneuron fate commitment" 11682 11682 'Alk' mRNA 20 20 39 0.18 0.19 0.39 0.01 0.01 0.05 0.253333333 0.023333333 1 1 6 26.33333333 2.666666667 1.04E-04 -3.331570702 05200///Pathways in cancer+++05223///Non-small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0006950///response to stress+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021766///hippocampus development+++GO:0030534///adult behavior+++GO:0033674///positive regulation of kinase activity+++GO:0036269///swimming behavior+++GO:0042127///regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045664///regulation of neuron differentiation+++GO:0046777///protein autophosphorylation+++GO:0048666///neuron development+++GO:0050995///negative regulation of lipid catabolic process+++GO:0060159///regulation of dopamine receptor signaling pathway+++GO:0090648///response to environmental enrichment+++GO:0097009///energy homeostasis+++GO:1900006///positive regulation of dendrite development 116837 116837 'Rims1' mRNA 10 11 6 0.07 0.09 0.05 0.01 0.03 0.05 0.07 0.03 1 4 6 9 3.666666667 0.26602655 -1.289575259 04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031982///vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0060077///inhibitory synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0098882///structural constituent of presynaptic active zone GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0010628///positive regulation of gene expression+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:0016081///synaptic vesicle docking+++GO:0016082///synaptic vesicle priming+++GO:0030154///cell differentiation+++GO:0042391///regulation of membrane potential+++GO:0048167///regulation of synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0050806///positive regulation of synaptic transmission+++GO:0060291///long-term synaptic potentiation+++GO:0060478///acrosomal vesicle exocytosis+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0065003///protein-containing complex assembly+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:1903861///positive regulation of dendrite extension+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential 116838 116838 'Rims2' mRNA 202 212 190 1.48 1.47 1.5 0.29 0.22 0.22 1.483333333 0.243333333 45 31 34 201.3333333 36.66666667 1.60E-23 -2.469557046 04911///Insulin secretion GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0060077///inhibitory synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0098882///structural constituent of presynaptic active zone GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007269///neurotransmitter secretion+++GO:0010628///positive regulation of gene expression+++GO:0016081///synaptic vesicle docking+++GO:0016082///synaptic vesicle priming+++GO:0017156///calcium ion regulated exocytosis+++GO:0017157///regulation of exocytosis+++GO:0019933///cAMP-mediated signaling+++GO:0030073///insulin secretion+++GO:0030154///cell differentiation+++GO:0042391///regulation of membrane potential+++GO:0048167///regulation of synaptic plasticity+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0050806///positive regulation of synaptic transmission+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:1903861///positive regulation of dendrite extension+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential 11684 11684 'Alox12' mRNA 179 188 173 3.26 3.36 3.34 2.21 2.65 2.3 3.32 2.386666667 140 164 141 180 148.3333333 0.185912245 -0.28897876 00590///Arachidonic acid metabolism+++01523///Antifolate resistance+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042383///sarcolemma "GO:0004052///arachidonate 12-lipoxygenase activity+++GO:0005506///iron ion binding+++GO:0016165///linoleate 13S-lipoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047977///hepoxilin-epoxide hydrolase activity+++GO:0050473///arachidonate 15-lipoxygenase activity+++GO:0051213///dioxygenase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007568///aging+++GO:0010628///positive regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0010942///positive regulation of cell death+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0019395///fatty acid oxidation+++GO:0033559///unsaturated fatty acid metabolic process+++GO:0034440///lipid oxidation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043651///linoleic acid metabolic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051122///hepoxilin biosynthetic process+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0061436///establishment of skin barrier+++GO:0071396///cellular response to lipid+++GO:0090331///negative regulation of platelet aggregation+++GO:1901751///leukotriene A4 metabolic process+++GO:1905956///positive regulation of endothelial tube morphogenesis+++GO:2001303///lipoxin A4 biosynthetic process+++GO:2001306///lipoxin B4 biosynthetic process 116847 116847 'Prelp' mRNA 2419 2579 2470 36.46 38.24 39.49 38.7 42.14 38.43 38.06333333 39.75666667 2955 3143 2842 2489.333333 2980 9.79E-04 0.247998463 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance GO:0007569///cell aging 116848 116848 'Baz2a' mRNA 1184 1213 978 7.38 7.4 6.44 6.77 6.21 6.71 7.073333333 6.563333333 1256 1123 1211 1125 1196.666667 0.458506768 0.080335417 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0033553///rDNA heterochromatin GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0070577///lysine-acetylated histone binding GO:0000183///chromatin silencing at rDNA+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0016479///negative regulation of transcription by RNA polymerase I+++GO:0016575///histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0034770///histone H4-K20 methylation+++GO:0051567///histone H3-K9 methylation+++GO:0070933///histone H4 deacetylation 11685 11685 'Alox12e' mRNA 136 128 138 3.28 3.02 3.53 1.62 2.3 1.67 3.276666667 1.863333333 77 107 77 134 87 0.015146496 -0.63439881 00590///Arachidonic acid metabolism+++01523///Antifolate resistance+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0004052///arachidonate 12-lipoxygenase activity+++GO:0005506///iron ion binding+++GO:0016165///linoleate 13S-lipoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0050473///arachidonate 15-lipoxygenase activity+++GO:0051213///dioxygenase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0034440///lipid oxidation+++GO:0043651///linoleic acid metabolic process+++GO:0051122///hepoxilin biosynthetic process 11687 11687 'Alox15' mRNA 158.34 145.4 131.35 0.65 0.66 0.47 0.91 0.64 0.61 0.593333333 0.72 123 107.47 119.01 145.03 116.4933333 0.174115444 -0.324981859 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04216///Ferroptosis+++04217///Necroptosis+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane "GO:0004052///arachidonate 12-lipoxygenase activity+++GO:0005506///iron ion binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0016165///linoleate 13S-lipoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0047977///hepoxilin-epoxide hydrolase activity+++GO:0050473///arachidonate 15-lipoxygenase activity+++GO:0051120///hepoxilin A3 synthase activity+++GO:0051213///dioxygenase activity" GO:0001503///ossification+++GO:0002820///negative regulation of adaptive immune response+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0019395///fatty acid oxidation+++GO:0030282///bone mineralization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034440///lipid oxidation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035358///regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0035963///cellular response to interleukin-13+++GO:0042060///wound healing+++GO:0043277///apoptotic cell clearance+++GO:0043651///linoleic acid metabolic process+++GO:0050727///regulation of inflammatory response+++GO:0051122///hepoxilin biosynthetic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071277///cellular response to calcium ion+++GO:1901074///regulation of engulfment of apoptotic cell+++GO:2001303///lipoxin A4 biosynthetic process 116870 116870 'Mta1' mRNA 365 421 269 7.23 8.17 5.64 5.38 5.09 4.67 7.013333333 5.046666667 313 288 262 351.6666667 287.6666667 0.100569448 -0.294656744 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016581///NuRD complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006302///double-strand break repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010212///response to ionizing radiation+++GO:0016575///histone deacetylation+++GO:0032922///circadian regulation of gene expression+++GO:0033363///secretory granule organization+++GO:0040029///regulation of gene expression, epigenetic+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045475///locomotor rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:1902499///positive regulation of protein autoubiquitination" 116871 116871 'Mta3' mRNA 767 835 737 18.96 20.24 18.96 15.78 14.58 14.96 19.38666667 15.10666667 699 599 661 779.6666667 653 0.0128847 -0.267236164 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016581///NuRD complex+++GO:0043231///intracellular membrane-bounded organelle GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 116873 116873 'Stim2' mRNA 1275 1224 859 13.88 13.09 9.91 4.49 4.28 4.52 12.29333333 4.43 475 443 463 1119.333333 460.3333333 3.24E-26 -1.286492006 04020///Calcium signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015279///store-operated calcium channel activity+++GO:0046872///metal ion binding GO:0002115///store-operated calcium entry+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0032237///activation of store-operated calcium channel activity+++GO:0051928///positive regulation of calcium ion transport+++GO:0070588///calcium ion transmembrane transport 11688 11688 'Alox8' mRNA 45.28 75.88 47.55 0.76 1.25 0.84 0.67 0.71 0.59 0.95 0.656666667 46.37 47.97 39.32 56.23666667 44.55333333 0.425762065 -0.345242007 00590///Arachidonic acid metabolism+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane "GO:0005506///iron ion binding+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0016165///linoleate 13S-lipoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0036403///arachidonate 8(S)-lipoxygenase activity+++GO:0046872///metal ion binding+++GO:0047677///arachidonate 8(R)-lipoxygenase activity+++GO:0050473///arachidonate 15-lipoxygenase activity+++GO:0051213///dioxygenase activity+++GO:1990136///linoleate 9S-lipoxygenase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0032722///positive regulation of chemokine production+++GO:0034440///lipid oxidation+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0043651///linoleic acid metabolic process+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045926///negative regulation of growth+++GO:0051122///hepoxilin biosynthetic process+++GO:0071926///endocannabinoid signaling pathway+++GO:1901696///cannabinoid biosynthetic process+++GO:2001303///lipoxin A4 biosynthetic process 11689 11689 'Alox5' mRNA 56 64 86 1.09 1.23 1.78 4.63 4.74 4.31 1.366666667 4.56 273 273 246 68.66666667 264 1.65E-18 1.924663273 00590///Arachidonic acid metabolism+++04664///Fc epsilon RI signaling pathway+++04726///Serotonergic synapse+++04913///Ovarian steroidogenesis+++05145///Toxoplasmosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005641///nuclear envelope lumen+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm "GO:0004051///arachidonate 5-lipoxygenase activity+++GO:0004052///arachidonate 12-lipoxygenase activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016787///hydrolase activity+++GO:0036403///arachidonate 8(S)-lipoxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002526///acute inflammatory response+++GO:0002540///leukotriene production involved in inflammatory response+++GO:0006691///leukotriene metabolic process+++GO:0006954///inflammatory response+++GO:0006959///humoral immune response+++GO:0016525///negative regulation of angiogenesis+++GO:0019233///sensory perception of pain+++GO:0019369///arachidonic acid metabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0019372///lipoxygenase pathway+++GO:0030501///positive regulation of bone mineralization+++GO:0034440///lipid oxidation+++GO:0036336///dendritic cell migration+++GO:0042593///glucose homeostasis+++GO:0043651///linoleic acid metabolic process+++GO:0045598///regulation of fat cell differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0050796///regulation of insulin secretion+++GO:0051122///hepoxilin biosynthetic process+++GO:0061044///negative regulation of vascular wound healing+++GO:0061045///negative regulation of wound healing+++GO:0106014///regulation of inflammatory response to wounding+++GO:1900015///regulation of cytokine production involved in inflammatory response+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1901753///leukotriene A4 biosynthetic process+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1904960///positive regulation of cytochrome-c oxidase activity+++GO:1904999///positive regulation of leukocyte adhesion to arterial endothelial cell+++GO:2001301///lipoxin biosynthetic process 116891 116891 'Derl2' mRNA 956.14 961.17 947.26 14.1 13.95 14.82 18.78 18.88 17.65 14.29 18.43666667 1463.29 1437.13 1332.14 954.8566667 1410.853333 8.87E-11 0.55097792 04141///Protein processing in endoplasmic reticulum GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005047///signal recognition particle binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0051787///misfolded protein binding+++GO:1990381///ubiquitin-specific protease binding "GO:0001967///suckling behavior+++GO:0006986///response to unfolded protein+++GO:0008284///positive regulation of cell proliferation+++GO:0030307///positive regulation of cell growth+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 11690 11690 'Alox5ap' mRNA 93 82 94 5.86 5.1 6.27 111.05 105.6 105.48 5.743333333 107.3766667 2025 1875 1858 89.66666667 1919.333333 9.04E-290 4.407271863 04664///Fc epsilon RI signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0004051///arachidonate 5-lipoxygenase activity+++GO:0004364///glutathione transferase activity+++GO:0004464///leukotriene-C4 synthase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0050544///arachidonic acid binding GO:0002540///leukotriene production involved in inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0006691///leukotriene metabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0019372///lipoxygenase pathway+++GO:0050790///regulation of catalytic activity+++GO:0070207///protein homotrimerization+++GO:0071277///cellular response to calcium ion+++GO:0098869///cellular oxidant detoxification 116903 116903 'Calcb' mRNA 31 29 28 0.61 0.45 0.5 1.94 1.76 1.69 0.52 1.796666667 73 71 71 29.33333333 71.66666667 2.73E-04 1.277616649 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031716///calcitonin receptor binding GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0051480///regulation of cytosolic calcium ion concentration 116904 116904 'Alpk3' mRNA 0 5 5 0 0.04 0.05 0.01 0.03 0.01 0.03 0.016666667 2 4 1 3.333333333 2.333333333 0.804977458 -0.533997723 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0016310///phosphorylation+++GO:0055007///cardiac muscle cell differentiation+++GO:0055013///cardiac muscle cell development 116905 116905 'Dph1' mRNA 332.69 332.69 308.1 8.96 8.82 8.8 9.51 8.36 9.83 8.86 9.233333333 406.11 348.62 406.34 324.4933333 387.0233333 0.102509005 0.243356111 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0090560///2-(3-amino-3-carboxypropyl)histidine synthase activity GO:0008283///cell proliferation+++GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine 116914 116914 'Slc19a2' mRNA 395 433 334 6.01 6.49 5.42 5.19 7.87 8.31 5.973333333 7.123333333 391 581 606 387.3333333 526 0.012955705 0.438068433 04977///Vitamin digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015234///thiamine transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity GO:0015888///thiamine transport+++GO:0035461///vitamin transmembrane transport+++GO:0051180///vitamin transport+++GO:0055085///transmembrane transport+++GO:0071934///thiamine transmembrane transport 11692 11692 'Gfer' mRNA 325.76 397.52 308.56 10.48 12.49 10.58 10.94 12.23 11.71 11.18333333 11.62666667 387.94 433.77 401.4 343.9466667 407.7033333 0.126801195 0.237931222 GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol GO:0008083///growth factor activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0016972///thiol oxidase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0001889///liver development+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0097421///liver regeneration+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:2000573///positive regulation of DNA biosynthetic process 116939 116939 'Pnpla3' mRNA 824 873 771 11.23 11.73 10.97 0.95 1.19 1.14 11.31 1.093333333 78.01 98 97 822.6666667 91.00333333 5.94E-110 -3.185495218 00561///Glycerolipid metabolism GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0004623///phospholipase A2 activity+++GO:0004806///triglyceride lipase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0035727///lysophosphatidic acid binding+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0051264///mono-olein transacylation activity+++GO:0051265///diolein transacylation activity" "GO:0001676///long-chain fatty acid metabolic process+++GO:0002021///response to dietary excess+++GO:0006629///lipid metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009744///response to sucrose+++GO:0016042///lipid catabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0019433///triglyceride catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0034389///lipid droplet organization+++GO:0036153///triglyceride acyl-chain remodeling+++GO:0050872///white fat cell differentiation+++GO:0055088///lipid homeostasis+++GO:1905243///cellular response to 3,3',5-triiodo-L-thyronine" 116940 116940 'Tgs1' mRNA 735 809 809 9.13 9.88 10.66 10.64 10.27 10.03 9.89 10.31333333 986 930 901 784.3333333 939 0.019844461 0.245942186 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015030///Cajal body GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0071164///RNA trimethylguanosine synthase activity GO:0001510///RNA methylation+++GO:0009452///7-methylguanosine RNA capping+++GO:0032259///methylation+++GO:0036261///7-methylguanosine cap hypermethylation 11695 11695 'Alx4' mRNA 4 7 1 0.04 0.07 0.01 0.01 0.03 0.02 0.04 0.02 1 3 2 4 2 0.593048413 -0.9789873 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001942///hair follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007517///muscle organ development+++GO:0009791///post-embryonic development+++GO:0009952///anterior/posterior pattern specification+++GO:0035108///limb morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048565///digestive tract development+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0060021///roof of mouth development" 116972 116972 'Tlcd3a' mRNA 190 162 152 5.25 4.41 4.42 6.15 6.34 6.21 4.693333333 6.233333333 257 257 251 168 255 8.56E-04 0.592220534 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0055088///lipid homeostasis 11699 11699 'Ambp' mRNA 1 0 0 0.05 0 0 0.38 0.3 0.3 0.016666667 0.326666667 9 7 7 0.333333333 7.666666667 0.011463005 4.405341933 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0019862///IgA binding+++GO:0020037///heme binding+++GO:0030414///peptidase inhibitor activity+++GO:0042803///protein homodimerization activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018298///protein-chromophore linkage+++GO:0030163///protein catabolic process+++GO:0051604///protein maturation 11702 11702 'Amd1' mRNA 5985.16 6026.81 5989.09 102.08 101.15 108.36 81.46 74.87 76.3 103.8633333 77.54333333 5495.43 4933.39 4984.91 6000.353333 5137.91 1.39E-04 -0.237550703 00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism GO:0005829///cytosol GO:0004014///adenosylmethionine decarboxylase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0019810///putrescine binding+++GO:0042802///identical protein binding GO:0001701///in utero embryonic development+++GO:0006557///S-adenosylmethioninamine biosynthetic process+++GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0006597///spermine biosynthetic process+++GO:0008295///spermidine biosynthetic process+++GO:0046500///S-adenosylmethionine metabolic process 11704 11704 'Amelx' mRNA 2 0 0 0.17 0 0 0.07 0 0 0.056666667 0.023333333 1 0 0 0.666666667 0.333333333 0.863090843 -0.883128046 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0030139///endocytic vesicle+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix+++GO:0099080///supramolecular complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0030345///structural constituent of tooth enamel+++GO:0031402///sodium ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046848///hydroxyapatite binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007584///response to nutrient+++GO:0031214///biomineral tissue development+++GO:0034505///tooth mineralization+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0051592///response to calcium ion+++GO:0070166///enamel mineralization+++GO:0097186///amelogenesis 11705 11705 'Amh' mRNA 0 1 0 0 0.03 0 0.03 0.03 0.03 0.01 0.03 1 1 1 0.333333333 1 0.709762031 1.469274488 04024///cAMP signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005102///signaling receptor binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity GO:0001546///preantral ovarian follicle growth+++GO:0001655///urogenital system development+++GO:0001880///Mullerian duct regression+++GO:0007165///signal transduction+++GO:0007506///gonadal mesoderm development+++GO:0007568///aging+++GO:0008406///gonad development+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0030154///cell differentiation+++GO:0042493///response to drug+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:2000355///negative regulation of ovarian follicle development 117109 117109 'Pop5' mRNA 760 806 803 48.68 51.06 54.83 41.84 44.18 44.06 51.52333333 43.36 754 784 783.03 789.6666667 773.6766667 0.761778722 -0.041894186 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030677///ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex GO:0000171///ribonuclease MRP activity+++GO:0004526///ribonuclease P activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0008033///tRNA processing+++GO:0016070///RNA metabolic process+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 117146 117146 'Ube3b' mRNA 1779 1749 1073 18.32 17.72 11.73 10.99 14.14 13.18 15.92333333 12.77 1229 1545 1428 1533.666667 1400.666667 0.679133211 -0.129119808 04120///Ubiquitin mediated proteolysis GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 117147 117147 'Acsm1' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00650///Butanoate metabolism+++00785///Lipoic acid metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004321///fatty-acyl-CoA synthase activity+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0015645///fatty acid ligase activity+++GO:0016874///ligase activity+++GO:0018858///benzoate-CoA ligase activity+++GO:0031956///medium-chain fatty acid-CoA ligase activity+++GO:0046872///metal ion binding+++GO:0047760///butyrate-CoA ligase activity+++GO:0102391///decanoate-CoA ligase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006637///acyl-CoA metabolic process 117148 117148 'Necab2' mRNA 2 1 5 0.09 0.04 0.18 0.11 0.19 0.31 0.103333333 0.203333333 3 5 8 2.666666667 5.333333333 0.530994084 0.968194159 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0031687///A2A adenosine receptor binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0042984///regulation of amyloid precursor protein biosynthetic process+++GO:0060168///positive regulation of adenosine receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1900451///positive regulation of glutamate receptor signaling pathway+++GO:1904021///negative regulation of G protein-coupled receptor internalization+++GO:1905477///positive regulation of protein localization to membrane 117149 117149 'Tirap' mRNA 797.92 798.09 813.29 9.04 8.87 9.76 9.64 8.19 9.16 9.223333333 8.996666667 980.99 814.81 901.82 803.1 899.2066667 0.193288926 0.148126254 04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05152///Tuberculosis+++05161///Hepatitis B+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0032587///ruffle membrane "GO:0003953///NAD+ nucleosidase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0035662///Toll-like receptor 4 binding+++GO:0035663///Toll-like receptor 2 binding+++GO:0042802///identical protein binding" GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007257///activation of JUN kinase activity+++GO:0009617///response to bacterium+++GO:0030099///myeloid cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031334///positive regulation of protein complex assembly+++GO:0032496///response to lipopolysaccharide+++GO:0032648///regulation of interferon-beta production+++GO:0032658///regulation of interleukin-15 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032738///positive regulation of interleukin-15 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0034146///toll-like receptor 5 signaling pathway+++GO:0035665///TIRAP-dependent toll-like receptor 4 signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0071221///cellular response to bacterial lipopeptide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:2000340///positive regulation of chemokine (C-X-C motif) ligand 1 production+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 117150 117150 'Pip4k2c' mRNA 1923 1951 1944 31.21 31.31 33.5 32.48 33.04 32.53 32.00666667 32.68333333 2296 2277 2225 1939.333333 2266 0.004280243 0.212022181 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04810///Regulation of actin cytoskeleton GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043229///intracellular organelle GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016309///1-phosphatidylinositol-5-phosphate 4-kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding "GO:0010506///regulation of autophagy+++GO:0016310///phosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0090217///negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:1902635///1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process+++GO:2000786///positive regulation of autophagosome assembly" 117160 117160 'Ttyh2' mRNA 506 510 518 7.97 7.9 8.65 24.19 22.56 20.84 8.173333333 22.53 1768 1610 1475 511.3333333 1617.666667 2.71E-67 1.647943899 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0072320///volume-sensitive chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport 117167 117167 'Steap4' mRNA 345 375 371 6.02 6.43 6.86 31.28 31.2 30.55 6.436666667 31.01 2064 2011 1952 363.6666667 2009 4.96E-166 2.453357627 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane GO:0008823///cupric reductase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0052851///ferric-chelate reductase (NADPH) activity+++GO:0071949///FAD binding GO:0006811///ion transport+++GO:0015677///copper ion import+++GO:0022900///electron transport chain+++GO:0033212///iron assimilation+++GO:0045444///fat cell differentiation+++GO:0055072///iron ion homeostasis+++GO:0070207///protein homotrimerization+++GO:0098706///ferric iron import across cell outer membrane 11717 11717 'Ampd3' mRNA 714.88 814.23 690.13 9.61 10.78 9.92 27.41 26.7 26.91 10.10333333 27.00666667 2328.03 2218.08 2223.81 739.7466667 2256.64 8.21E-94 1.599421234 00230///Purine metabolism GO:0005829///cytosol GO:0003876///AMP deaminase activity+++GO:0016787///hydrolase activity+++GO:0019239///deaminase activity+++GO:0046872///metal ion binding GO:0006188///IMP biosynthetic process+++GO:0006196///AMP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0034101///erythrocyte homeostasis+++GO:0046031///ADP metabolic process+++GO:0046032///ADP catabolic process+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046039///GTP metabolic process+++GO:0097009///energy homeostasis 117171 117171 '1110038F14Rik' mRNA 683 723 561 25.54 26.35 22.09 23.58 26.27 24.83 24.66 24.89333333 725 796 744 655.6666667 755 0.10224529 0.196918815 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 117197 117197 'Bloc1s4' mRNA 465 413 120 21.52 18.87 5.89 8.06 24.18 18.59 15.42666667 16.94333333 200 585 446 332.6666667 410.3333333 0.739884521 0.325515934 GO:0005737///cytoplasm+++GO:0031083///BLOC-1 complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0008089///anterograde axonal transport+++GO:0031175///neuron projection development+++GO:0032438///melanosome organization+++GO:0048490///anterograde synaptic vesicle transport+++GO:0050885///neuromuscular process controlling balance+++GO:0070527///platelet aggregation 117198 117198 'Ivns1abp' mRNA 4447 4683 4817 65.31 67.83 74.44 59.18 62.1 59.66 69.19333333 60.31333333 4547 4606 4422 4649 4525 0.550556908 -0.052734124 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0008380///RNA splicing+++GO:0009615///response to virus+++GO:0022900///electron transport chain+++GO:0031397///negative regulation of protein ubiquitination+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 11720 11720 'Mat1a' mRNA 40 20 36 0.64 0.32 0.6 0.06 0.13 0.01 0.52 0.066666667 4 9 1 32 4.666666667 1.24E-04 -2.792649351 00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004478///methionine adenosyltransferase activity+++GO:0005524///ATP binding+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0046872///metal ion binding GO:0006556///S-adenosylmethionine biosynthetic process+++GO:0006730///one-carbon metabolic process+++GO:0009087///methionine catabolic process+++GO:0051289///protein homotetramerization+++GO:0065003///protein-containing complex assembly 11722 11722 'Amy1' mRNA 449 413 366 15.44 14.22 13.52 5.12 5.68 5.76 14.39333333 5.52 173 189 187 409.3333333 183 5.77E-15 -1.169887068 00500///Starch and sucrose metabolism+++04970///Salivary secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space "GO:0003824///catalytic activity+++GO:0004556///alpha-amylase activity+++GO:0005509///calcium ion binding+++GO:0016160///amylase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0031404///chloride ion binding+++GO:0043169///cation binding+++GO:0046872///metal ion binding+++GO:0103025///alpha-amylase activity (releasing maltohexaose)" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0009617///response to bacterium+++GO:0016052///carbohydrate catabolic process 117229 117229 'Stk33' mRNA 172 178 186 4.64 5.04 5.45 0.58 0.43 0.5 5.043333333 0.503333333 28 18 19 178.6666667 21.66666667 4.72E-26 -3.059808159 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0042770///signal transduction in response to DNA damage+++GO:0044773///mitotic DNA damage checkpoint+++GO:0046777///protein autophosphorylation 11727 11727 'Ang' mRNA 80.3 66.43 49.22 6.53 5.14 4.09 25.43 31.2 28.04 5.253333333 28.22333333 396.24 446.66 401.75 65.31666667 414.8833333 8.15E-45 2.666381656 05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0015629///actin cytoskeleton+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0032311///angiogenin-PRI complex+++GO:0043025///neuronal cell body GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003779///actin binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005102///signaling receptor binding+++GO:0005507///copper ion binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001878///response to yeast+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006651///diacylglycerol biosynthetic process+++GO:0007202///activation of phospholipase C activity+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0009303///rRNA transcription+++GO:0009725///response to hormone+++GO:0016477///cell migration+++GO:0017148///negative regulation of translation+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0030041///actin filament polymerization+++GO:0030154///cell differentiation+++GO:0032148///activation of protein kinase B activity+++GO:0032431///activation of phospholipase A2 activity+++GO:0042327///positive regulation of phosphorylation+++GO:0045087///innate immune response+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 11731 11731 'Ang2' mRNA 1 0 1 0.21 0 0.23 0.75 1.94 0.59 0.146666667 1.093333333 4 10 3 0.666666667 5.666666667 0.086361322 3.073734033 05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0015629///actin cytoskeleton+++GO:0031410///cytoplasmic vesicle GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005102///signaling receptor binding+++GO:0005507///copper ion binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001878///response to yeast+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0003300///cardiac muscle hypertrophy+++GO:0006651///diacylglycerol biosynthetic process+++GO:0007202///activation of phospholipase C activity+++GO:0009303///rRNA transcription+++GO:0009725///response to hormone+++GO:0016477///cell migration+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0032148///activation of protein kinase B activity+++GO:0032431///activation of phospholipase A2 activity+++GO:0042327///positive regulation of phosphorylation+++GO:0045087///innate immune response+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071333///cellular response to glucose stimulus 11732 11732 'Ank' mRNA 1976 2015 1779 30.72 30.82 29.34 23.2 24.16 24.26 30.29333333 23.87333333 1717 1747 1739 1923.333333 1734.333333 0.036706939 -0.158817852 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0015114///phosphate ion transmembrane transporter activity+++GO:0030504///inorganic diphosphate transmembrane transporter activity GO:0006817///phosphate ion transport+++GO:0030500///regulation of bone mineralization+++GO:0030505///inorganic diphosphate transport+++GO:0035435///phosphate ion transmembrane transport 11733 11733 'Ank1' mRNA 229.17 302.78 182.62 1.55 2.12 1.25 0.32 0.43 0.52 1.64 0.423333333 60.08 74.95 74.03 238.19 69.68666667 1.55E-14 -1.779048846 04624///Toll and Imd signaling pathway+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014731///spectrin-associated cytoskeleton+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030673///axolemma+++GO:0030863///cortical cytoskeleton+++GO:0031430///M band+++GO:0031672///A band+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane GO:0005515///protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0030507///spectrin binding+++GO:0044325///ion channel binding+++GO:0051117///ATPase binding GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007165///signal transduction+++GO:0010638///positive regulation of organelle organization+++GO:0048821///erythrocyte development+++GO:0055072///iron ion homeostasis+++GO:0072659///protein localization to plasma membrane+++GO:0098662///inorganic cation transmembrane transport 11735 11735 'Ank3' mRNA 4490.1 4566.43 4297.55 16.6 16.76 16.84 6.84 5.83 6.23 16.73333333 6.3 2418.85 1970.51 2116.04 4451.36 2168.466667 1.10E-51 -1.050889851 04624///Toll and Imd signaling pathway+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0014731///spectrin-associated cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0033268///node of Ranvier+++GO:0033270///paranode region of axon+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043194///axon initial segment+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane "GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0030507///spectrin binding+++GO:0030674///protein binding, bridging+++GO:0044325///ion channel binding+++GO:0045296///cadherin binding+++GO:0140031///phosphorylation-dependent protein binding" GO:0000281///mitotic cytokinesis+++GO:0007009///plasma membrane organization+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007528///neuromuscular junction development+++GO:0010628///positive regulation of gene expression+++GO:0010650///positive regulation of cell communication by electrical coupling+++GO:0010765///positive regulation of sodium ion transport+++GO:0010960///magnesium ion homeostasis+++GO:0019228///neuronal action potential+++GO:0034112///positive regulation of homotypic cell-cell adhesion+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0043266///regulation of potassium ion transport+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0045184///establishment of protein localization+++GO:0045760///positive regulation of action potential+++GO:0045838///positive regulation of membrane potential+++GO:0050808///synapse organization+++GO:0071286///cellular response to magnesium ion+++GO:0071709///membrane assembly+++GO:0072659///protein localization to plasma membrane+++GO:0072660///maintenance of protein location in plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0099612///protein localization to axon+++GO:1900827///positive regulation of membrane depolarization during cardiac muscle cell action potential+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity+++GO:2001259///positive regulation of cation channel activity 11736 11736 'Ankfy1' mRNA 1181.3 1194.56 1145.63 7.76 7.73 7.97 13.06 12.07 11.7 7.82 12.27666667 2296.17 2074.09 1992.55 1173.83 2120.936667 5.18E-28 0.841311088 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044354///macropinosome GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:1901981///phosphatidylinositol phosphate binding "GO:0006897///endocytosis+++GO:0016197///endosomal transport+++GO:0034058///endosomal vesicle fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048549///positive regulation of pinocytosis+++GO:0090160///Golgi to lysosome transport" 11737 11737 'Anp32a' mRNA 475.37 407.32 373.78 12.83 10.77 10.68 15.18 14.3 15.64 11.42666667 15.04 645.61 595.26 645.52 418.8233333 628.7966667 1.93E-06 0.577003446 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016363///nuclear matrix+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0042393///histone binding GO:0006913///nucleocytoplasmic transport+++GO:0042981///regulation of apoptotic process 11739 11739 'Slc25a4' mRNA 14281 14815 14683 645.88 661.3 704.54 519.25 531.24 506.73 670.5733333 519.0733333 13182 13156 12442 14593 12926.66667 0.001639512 -0.187833086 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0043209///myelin sheath+++GO:0045121///membrane raft GO:0005471///ATP:ADP antiporter activity+++GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0017077///oxidative phosphorylation uncoupler activity+++GO:0019899///enzyme binding GO:0008637///apoptotic mitochondrial changes+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0015866///ADP transport+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0055085///transmembrane transport+++GO:0060546///negative regulation of necroptotic process+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0140021///mitochondrial ADP transmembrane transport+++GO:1901526///positive regulation of mitophagy+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902600///proton transmembrane transport+++GO:1990544///mitochondrial ATP transmembrane transport+++GO:1990845///adaptive thermogenesis+++GO:2000277///positive regulation of oxidative phosphorylation uncoupler activity 11740 11740 'Slc25a5' mRNA 6606 6691 6624 308.84 308.78 328.56 437.82 453.23 435.48 315.3933333 442.1766667 10751 10856 10342 6640.333333 10649.66667 6.59E-33 0.669061082 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0071817///MMXD complex GO:0000295///adenine nucleotide transmembrane transporter activity+++GO:0005471///ATP:ADP antiporter activity+++GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0017077///oxidative phosphorylation uncoupler activity+++GO:0031625///ubiquitin protein ligase binding GO:0007059///chromosome segregation+++GO:0008284///positive regulation of cell proliferation+++GO:0030183///B cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0051503///adenine nucleotide transport+++GO:0055085///transmembrane transport+++GO:0140021///mitochondrial ADP transmembrane transport+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1901526///positive regulation of mitophagy+++GO:1990544///mitochondrial ATP transmembrane transport+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1990845///adaptive thermogenesis 11744 11744 'Anxa11' mRNA 721 642 353 16.84 14.76 8.74 14.07 13.27 13.11 13.44666667 13.48333333 693 638 626 572 652.3333333 0.353008205 0.190048364 05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0042470///melanosome+++GO:0042581///specific granule+++GO:0042582///azurophil granule+++GO:0045335///phagocytic vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0044548///S100 protein binding+++GO:0048306///calcium-dependent protein binding GO:0006909///phagocytosis+++GO:0007049///cell cycle+++GO:0032506///cytokinetic process+++GO:0051301///cell division+++GO:0051592///response to calcium ion 11745 11745 'Anxa3' mRNA 252 307 294 9.24 11.03 11.4 111.23 112.44 109.14 10.55666667 110.9366667 3491 3442 3316 284.3333333 3416.333333 0 3.574634932 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030670///phagocytic vesicle membrane+++GO:0042581///specific granule+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix GO:0004859///phospholipase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019834///phospholipase A2 inhibitor activity+++GO:0048306///calcium-dependent protein binding GO:0006909///phagocytosis+++GO:0010595///positive regulation of endothelial cell migration+++GO:0021766///hippocampus development+++GO:0031100///animal organ regeneration+++GO:0042742///defense response to bacterium+++GO:0043086///negative regulation of catalytic activity+++GO:0043312///neutrophil degranulation+++GO:0045766///positive regulation of angiogenesis+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051384///response to glucocorticoid+++GO:0070848///response to growth factor 11746 11746 'Anxa4' mRNA 2107 2066 2200 64.3 61.55 70.48 94.47 94.32 93.12 65.44333333 93.97 3736 3646 3585 2124.333333 3655.666667 2.57E-27 0.769082224 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0051059///NF-kappaB binding GO:0001822///kidney development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032717///negative regulation of interleukin-8 production 11747 11747 'Anxa5' mRNA 18165 18785 17850 610.6 622.42 636.53 529.27 522.17 524.74 623.1833333 525.3933333 18095 17424 17360 18266.66667 17626.33333 0.252710414 -0.063514243 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009897///external side of plasma membrane+++GO:0014704///intercalated disc+++GO:0030018///Z disc+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0062023///collagen-containing extracellular matrix+++GO:0072563///endothelial microparticle GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0017046///peptide hormone binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010033///response to organic substance+++GO:0030195///negative regulation of blood coagulation+++GO:0043065///positive regulation of apoptotic process+++GO:0050819///negative regulation of coagulation+++GO:0051592///response to calcium ion+++GO:0070588///calcium ion transmembrane transport+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:1901317///regulation of flagellated sperm motility+++GO:1902721///negative regulation of prolactin secretion 11749 11749 'Anxa6' mRNA 3890 4083 4156 81.01 83.7 91.8 96.06 98.28 97.13 85.50333333 97.15666667 5306 5303 5196 4043 5268.333333 3.51E-08 0.368449975 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0001786///phosphatidylserine binding+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0015276///ligand-gated ion channel activity+++GO:0015485///cholesterol binding+++GO:0035374///chondroitin sulfate binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding GO:0001755///neural crest cell migration+++GO:0001778///plasma membrane repair+++GO:0003418///growth plate cartilage chondrocyte differentiation+++GO:0006816///calcium ion transport+++GO:0006937///regulation of muscle contraction+++GO:0034220///ion transmembrane transport+++GO:0051283///negative regulation of sequestering of calcium ion+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0097190///apoptotic signaling pathway 11750 11750 'Anxa7' mRNA 1698 1858 1697 33.55 36.44 36.07 34.75 34.61 35.31 35.35333333 34.89 1982 1977 1956 1751 1971.666667 0.039005099 0.160149306 05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031982///vesicle+++GO:0042584///chromaffin granule membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0048306///calcium-dependent protein binding GO:0006874///cellular calcium ion homeostasis+++GO:0006914///autophagy+++GO:0007599///hemostasis+++GO:0008283///cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009651///response to salt stress+++GO:0009992///cellular water homeostasis+++GO:0010629///negative regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0030855///epithelial cell differentiation+++GO:0051592///response to calcium ion+++GO:0061025///membrane fusion 11752 11752 'Anxa8' mRNA 5 13 3 0.15 0.39 0.1 1.22 1.03 0.9 0.213333333 1.05 46 38 33 7 39 4.72E-05 2.478321535 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031902///late endosome membrane "GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding" GO:0007032///endosome organization+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0016197///endosomal transport+++GO:1900004///negative regulation of serine-type endopeptidase activity+++GO:1900138///negative regulation of phospholipase A2 activity 11754 11754 'Aoc3' mRNA 17 8 21 0.21 0.1 0.28 0.08 0.05 0.18 0.196666667 0.103333333 7 5 16 15.33333333 9.333333333 0.411744707 -0.742195683 "00260///Glycine, serine and threonine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism" GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0008131///primary amine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0048038///quinone binding+++GO:0052593///tryptamine:oxygen oxidoreductase (deaminating) activity+++GO:0052594///aminoacetone:oxygen oxidoreductase(deaminating) activity+++GO:0052595///aliphatic-amine oxidase activity+++GO:0052596///phenethylamine:oxygen oxidoreductase (deaminating) activity GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0002687///positive regulation of leukocyte migration+++GO:0007155///cell adhesion+++GO:0008217///regulation of blood pressure+++GO:0009308///amine metabolic process+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0035902///response to immobilization stress+++GO:0042755///eating behavior+++GO:0046677///response to antibiotic+++GO:1902283///negative regulation of primary amine oxidase activity 11757 11757 'Prdx3' mRNA 1679 1832 1684 69.06 74.34 73.48 85.16 85.41 84.74 72.29333333 85.10333333 2378 2327 2289 1731.666667 2331.333333 2.72E-09 0.417592644 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0008022///protein C-terminus binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0051920///peroxiredoxin activity GO:0001893///maternal placenta development+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0008284///positive regulation of cell proliferation+++GO:0018171///peptidyl-cysteine oxidation+++GO:0030099///myeloid cell differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0033673///negative regulation of kinase activity+++GO:0034599///cellular response to oxidative stress+++GO:0034614///cellular response to reactive oxygen species+++GO:0042542///response to hydrogen peroxide+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0098869///cellular oxidant detoxification 11758 11758 'Prdx6' mRNA 5996 6221 5912 173.05 177.74 179.28 146.54 149.27 151.47 176.69 149.0933333 5825 5788 5854 6043 5822.333333 0.312543471 -0.065304771 00480///Glutathione metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm "GO:0003824///catalytic activity+++GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004623///phospholipase A2 activity+++GO:0005515///protein binding+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0051920///peroxiredoxin activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" "GO:0000302///response to reactive oxygen species+++GO:0006629///lipid metabolic process+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0016042///lipid catabolic process+++GO:0032060///bleb assembly+++GO:0042744///hydrogen peroxide catabolic process+++GO:0045454///cell redox homeostasis+++GO:0046475///glycerophospholipid catabolic process+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0098869///cellular oxidant detoxification" 117589 117589 'Asb7' mRNA 481 484 359 5.17 5.08 4.16 3.14 3.03 2.77 4.803333333 2.98 336 317 284 441.3333333 312.3333333 6.16E-04 -0.505568907 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 117590 117590 'Asb10' mRNA 7 1 6 0.17 0.02 0.16 0.57 0.29 0.41 0.116666667 0.423333333 27 13 18 4.666666667 19.33333333 0.016658423 2.022940582 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 117591 117591 'Slc2a9' mRNA 11 20 5 0.18 0.33 0.08 0.63 0.52 0.45 0.196666667 0.533333333 47 39 33 12 39.66666667 0.002051631 1.727332302 GO:0005635///nuclear envelope+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0005355///glucose transmembrane transporter activity+++GO:0015143///urate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015747///urate transport+++GO:0015755///fructose transmembrane transport+++GO:0046415///urate metabolic process+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 117592 117592 'B3galt6' mRNA 488 519 491 8.3 8.69 8.86 6.33 6.4 5.88 8.616666667 6.203333333 428 423 385 499.3333333 412 0.025307821 -0.289230859 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0035250///UDP-galactosyltransferase activity+++GO:0047220///galactosylxylosylprotein 3-beta-galactosyltransferase activity" GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006486///protein glycosylation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process 117599 117599 'Helb' mRNA 118.17 147 134 1.4 1.71 1.68 2.91 2.37 2.18 1.596666667 2.486666667 283 225 205 133.0566667 237.6666667 4.43E-05 0.823237827 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005662///DNA replication factor A complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0035861///site of double-strand break GO:0000166///nucleotide binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0043139///5'-3' DNA helicase activity+++GO:0044877///protein-containing complex binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032508///DNA duplex unwinding+++GO:1903775///regulation of DNA double-strand break processing+++GO:2000042///negative regulation of double-strand break repair via homologous recombination" 117600 117600 'Srgap1' mRNA 1144 1076 997 7.73 7.14 7.13 2.17 2.21 2.07 7.333333333 2.15 370 367 343 1072.333333 360 3.82E-55 -1.585099618 04360///Axon guidance GO:0005737///cytoplasm GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0016477///cell migration+++GO:0030336///negative regulation of cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 117606 117606 'Boc' mRNA 1424 1344 1356 17.27 16.03 17.45 11.02 9.84 12.26 16.91666667 11.04 1046 912 1127 1374.666667 1028.333333 7.05E-06 -0.431755584 04340///Hedgehog signaling pathway+++04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007224///smoothened signaling pathway+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0016202///regulation of striated muscle tissue development+++GO:0030030///cell projection organization+++GO:0045663///positive regulation of myoblast differentiation+++GO:0098609///cell-cell adhesion 11761 11761 'Aox1' mRNA 169 157 194 2.08 1.91 2.53 1.95 2.35 2.23 2.173333333 2.176666667 181 214 201 173.3333333 198.6666667 0.444328605 0.181974538 "00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00380///Tryptophan metabolism+++00750///Vitamin B6 metabolism+++00760///Nicotinate and nicotinamide metabolism+++00830///Retinol metabolism+++00982///Drug metabolism - cytochrome P450+++04630///JAK-STAT signaling pathway" GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004031///aldehyde oxidase activity+++GO:0005506///iron ion binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050250///retinal oxidase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0071949///FAD binding+++GO:0102797///geranial:oxygen oxidoreductase activity+++GO:0102798///heptaldehyde:oxygen oxidoreductase activity" GO:0006805///xenobiotic metabolic process+++GO:0017144///drug metabolic process+++GO:0022900///electron transport chain 11764 11764 'Ap1b1' mRNA 3117 3127 3267.62 42.11 41.45 46.84 46.56 45.34 41.78 43.46666667 44.56 3965 3777 3456 3170.54 3732.666667 0.004509592 0.221180096 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030131///clathrin adaptor complex+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding GO:0001822///kidney development+++GO:0006886///intracellular protein transport+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048268///clathrin coat assembly 11765 11765 'Ap1g1' mRNA 1323 1381 1232 10.17 10.44 10.04 8.36 8.26 9.19 10.21666667 8.603333333 1252 1209 1333 1312 1264.666667 0.537288807 -0.063295221 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030121///AP-1 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008022///protein C-terminus binding+++GO:0019894///kinesin binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding+++GO:0035615///clathrin adaptor activity GO:0000226///microtubule cytoskeleton organization+++GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0035646///endosome to melanosome transport+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0090160///Golgi to lysosome transport 11766 11766 'Ap1g2' mRNA 201.22 214 215.49 4.21 4.37 4.74 11.25 9.37 8.31 4.44 9.643333333 624.02 508 446.45 210.2366667 526.1566667 7.74E-18 1.309571662 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030121///AP-1 adaptor complex+++GO:0030133///transport vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 11767 11767 'Ap1m1' mRNA 1156 1108 1125 30.91 29.29 31.87 35.94 38.21 38.41 30.69 37.52 1532 1597 1584 1129.666667 1571 2.44E-08 0.463877736 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030131///clathrin adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032438///melanosome organization+++GO:0035646///endosome to melanosome transport 11768 11768 'Ap1m2' mRNA 2204 2258 2200 69.04 70.47 74.24 38.93 40.01 40.15 71.25 39.69666667 1392 1397 1389 2220.666667 1392.666667 1.63E-21 -0.685181901 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030131///clathrin adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0035615///clathrin adaptor activity GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 11769 11769 'Ap1s1' mRNA 1100 1215 1156 49.17 53.28 55.47 76.94 78.98 80.12 52.64 78.68 1957 1959 1974 1157 1963.333333 7.47E-22 0.750978407 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030121///AP-1 adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity "GO:0006886///intracellular protein transport+++GO:0009615///response to virus+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi" 11770 11770 'Fabp4' mRNA 1 1 0 0.11 0.11 0 12.41 13.49 14.37 0.073333333 13.42333333 132 141 149 0.666666667 140.6666667 1.19E-12 7.712554682 03320///PPAR signaling pathway+++04923///Regulation of lipolysis in adipocytes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005324///long-chain fatty acid transporter activity+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0036041///long-chain fatty acid binding+++GO:0051427///hormone receptor binding "GO:0001816///cytokine production+++GO:0006469///negative regulation of protein kinase activity+++GO:0006631///fatty acid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0042632///cholesterol homeostasis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0071285///cellular response to lithium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0120162///positive regulation of cold-induced thermogenesis" 11771 11771 'Ap2a1' mRNA 1858.26 1815.11 1503.42 30.03 28.84 25.75 25.34 23.25 25.04 28.20666667 24.54333333 1807.18 1619.15 1729.27 1725.596667 1718.533333 0.887233713 -0.014762374 04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030117///membrane coat+++GO:0030122///AP-2 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030141///secretory granule+++GO:0032433///filopodium tip+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0035615///clathrin adaptor activity+++GO:0044877///protein-containing complex binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0072583///clathrin-dependent endocytosis+++GO:1900126///negative regulation of hyaluronan biosynthetic process 11772 11772 'Ap2a2' mRNA 2332.86 2372.35 2415.99 26.95 26.95 29.6 40.64 37.73 37.96 27.83333333 38.77666667 4050.16 3673.52 3664.19 2373.733333 3795.956667 3.83E-22 0.66358263 04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030122///AP-2 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding+++GO:0035615///clathrin adaptor activity+++GO:0044877///protein-containing complex binding+++GO:0097718///disordered domain specific binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0072583///clathrin-dependent endocytosis+++GO:1902036///regulation of hematopoietic stem cell differentiation 11773 11773 'Ap2m1' mRNA 7830.36 7759.61 8042.15 146.71 143.07 159.84 178.97 190.65 180.66 149.8733333 183.4266667 10988.79 11431.75 10739.78 7877.373333 11053.44 4.74E-14 0.475524612 04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005048///signal sequence binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0035615///clathrin adaptor activity+++GO:0044325///ion channel binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0097718///disordered domain specific binding GO:0002092///positive regulation of receptor internalization+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006900///vesicle budding from membrane+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0031623///receptor internalization+++GO:0048488///synaptic vesicle endocytosis+++GO:0065003///protein-containing complex assembly+++GO:0072583///clathrin-dependent endocytosis+++GO:0097494///regulation of vesicle size+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1903077///negative regulation of protein localization to plasma membrane 11774 11774 'Ap3b1' mRNA 1327.16 1484.39 1420.87 16.53 17.71 18.95 20.94 18.99 19.34 17.73 19.75666667 1872.22 1669.16 1690.93 1410.806667 1744.103333 5.86E-04 0.292664781 04142///Lysosome GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030123///AP-3 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:1904115///axon cytoplasm GO:0019903///protein phosphatase binding+++GO:0030276///clathrin binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding "GO:0000902///cell morphogenesis+++GO:0002224///toll-like receptor signaling pathway+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003016///respiratory system process+++GO:0006464///cellular protein modification process+++GO:0006622///protein targeting to lysosome+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006954///inflammatory response+++GO:0007040///lysosome organization+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007596///blood coagulation+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016182///synaptic vesicle budding from endosome+++GO:0016192///vesicle-mediated transport+++GO:0017157///regulation of exocytosis+++GO:0019882///antigen processing and presentation+++GO:0030324///lung development+++GO:0030851///granulocyte differentiation+++GO:0032438///melanosome organization+++GO:0032606///type I interferon production+++GO:0032607///interferon-alpha production+++GO:0034394///protein localization to cell surface+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043473///pigmentation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048007///antigen processing and presentation, exogenous lipid antigen via MHC class Ib+++GO:0048490///anterograde synaptic vesicle transport+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0048872///homeostasis of number of cells+++GO:0050790///regulation of catalytic activity+++GO:0051138///positive regulation of NK T cell differentiation+++GO:0060155///platelet dense granule organization+++GO:0060425///lung morphogenesis+++GO:0061024///membrane organization+++GO:0090152///establishment of protein localization to mitochondrial membrane involved in mitochondrial fission+++GO:0098773///skin epidermis development" 11775 11775 'Ap3b2' mRNA 6828 7157 6924 94.45 97.34 101.56 7.32 7.23 7.56 97.78333333 7.37 610 586 609 6969.666667 601.6666667 0 -3.546597265 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030123///AP-3 adaptor complex+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:1904115///axon cytoplasm GO:0006886///intracellular protein transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048490///anterograde synaptic vesicle transport 11776 11776 'Ap3d1' mRNA 4295 4473 4211 47.73 48.89 49.63 41.42 38.63 39.3 48.75 39.78333333 4289 3908 3943 4326.333333 4046.666667 0.094368688 -0.108744815 04142///Lysosome GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030123///AP-3 adaptor complex+++GO:0030424///axon+++GO:0043195///terminal bouton+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098830///presynaptic endosome+++GO:0098978///glutamatergic synapse+++GO:1904115///axon cytoplasm "GO:0006623///protein targeting to vacuole+++GO:0006829///zinc ion transport+++GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016182///synaptic vesicle budding from endosome+++GO:0016192///vesicle-mediated transport+++GO:0019882///antigen processing and presentation+++GO:0032607///interferon-alpha production+++GO:0033365///protein localization to organelle+++GO:0035646///endosome to melanosome transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048007///antigen processing and presentation, exogenous lipid antigen via MHC class Ib+++GO:0048490///anterograde synaptic vesicle transport+++GO:0048499///synaptic vesicle membrane organization+++GO:0051138///positive regulation of NK T cell differentiation+++GO:0061088///regulation of sequestering of zinc ion+++GO:0072657///protein localization to membrane+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0099003///vesicle-mediated transport in synapse" 11777 11777 'Ap3s1' mRNA 632.83 638 504 25.24 24.61 20.91 33.38 35.69 39.36 23.58666667 36.14333333 980 1001 1110 591.61 1030.333333 5.51E-14 0.794035516 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030123///AP-3 adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1904115///axon cytoplasm GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048490///anterograde synaptic vesicle transport 11778 11778 'Ap3s2' mRNA 1308 1226 1210 11.97 11.03 11.75 9.45 10.18 9.58 11.58333333 9.736666667 1189 1251 1168 1248 1202.666667 0.549731039 -0.064568155 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030123///AP-3 adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1904115///axon cytoplasm GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048490///anterograde synaptic vesicle transport 11781 11781 'Ap4m1' mRNA 353.11 355.21 343.46 6.42 6.27 6.52 5.13 4.85 4.77 6.403333333 4.916666667 308.37 285.58 274.21 350.5933333 289.3866667 0.054481992 -0.290003902 04142///Lysosome GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030124///AP-4 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0006605///protein targeting+++GO:0006622///protein targeting to lysosome+++GO:0006886///intracellular protein transport+++GO:0006895///Golgi to endosome transport+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0090160///Golgi to lysosome transport+++GO:1903361///protein localization to basolateral plasma membrane 11782 11782 'Ap4s1' mRNA 1757.35 1759.75 1563.4 25.78 26.79 26.01 20.31 23.13 22.22 26.19333333 21.88666667 1969.24 1725.9 1933.07 1693.5 1876.07 0.096630563 0.137049654 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030124///AP-4 adaptor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 11783 11783 'Apaf1' mRNA 114 112 104 0.94 0.94 0.91 3.01 2.35 2.79 0.93 2.716666667 423 324 378 110 375 9.94E-25 1.756603964 01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05134///Legionellosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043293///apoptosome GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0042981///regulation of apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0097190///apoptotic signaling pathway+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:2001235///positive regulation of apoptotic signaling pathway 11784 11784 'Apba2' mRNA 22 16 23 0.36 0.25 0.39 0.46 0.44 0.3 0.333333333 0.4 32 30 20 20.33333333 27.33333333 0.513945021 0.408725308 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0043197///dendritic spine+++GO:0098685///Schaffer collateral - CA1 synapse GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001701///in utero embryonic development+++GO:0007268///chemical synaptic transmission+++GO:0007626///locomotory behavior+++GO:0010468///regulation of gene expression+++GO:0015031///protein transport+++GO:0035264///multicellular organism growth+++GO:2000300///regulation of synaptic vesicle exocytosis 11785 11785 'Apbb1' mRNA 2019 2152 2075 43.01 45.85 47.62 21.28 21.17 20.59 45.49333333 21.01333333 1171 1097 1099 2082 1122.333333 7.99E-33 -0.904228839 05010///Alzheimer disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044304///main axon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:1990761///growth cone lamellipodium+++GO:1990812///growth cone filopodium GO:0001540///amyloid-beta binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035035///histone acetyltransferase binding+++GO:0042393///histone binding+++GO:0044877///protein-containing complex binding+++GO:0048156///tau protein binding+++GO:0070064///proline-rich region binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0006939///smooth muscle contraction+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007050///cell cycle arrest+++GO:0007411///axon guidance+++GO:0008542///visual learning+++GO:0010039///response to iron ion+++GO:0010976///positive regulation of neuron projection development+++GO:0030048///actin filament-based movement+++GO:0030198///extracellular matrix organization+++GO:0030308///negative regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050714///positive regulation of protein secretion+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:1902807///negative regulation of cell cycle G1/S phase transition" 11787 11787 'Apbb2' mRNA 1418.65 1490.34 1421.63 11.12 11.48 11.82 9.61 8.78 9.59 11.47333333 9.326666667 1405.7 1265.21 1370.73 1443.54 1347.213333 0.216604656 -0.112209834 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035035///histone acetyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006939///smooth muscle contraction+++GO:0007050///cell cycle arrest+++GO:0007411///axon guidance+++GO:0030048///actin filament-based movement+++GO:0030198///extracellular matrix organization+++GO:0030308///negative regulation of cell growth+++GO:0036438///maintenance of lens transparency+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:1901988///negative regulation of cell cycle phase transition" 11789 11789 'Apc' mRNA 2289 2313 2132 11.65 11.44 11.65 6.84 6.33 6.96 11.58 6.71 1543 1446 1576 2244.666667 1521.666667 2.28E-16 -0.57191284 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0030877///beta-catenin destruction complex+++GO:0031253///cell projection membrane+++GO:0031965///nuclear membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0034750///Scrib-APC-beta-catenin complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070852///cell body fiber GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008017///microtubule binding+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0045295///gamma-catenin binding+++GO:0051010///microtubule plus-end binding+++GO:0070840///dynein complex binding GO:0000281///mitotic cytokinesis+++GO:0001708///cell fate specification+++GO:0001822///kidney development+++GO:0001942///hair follicle development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007050///cell cycle arrest+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0009798///axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0010942///positive regulation of cell death+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0019827///stem cell population maintenance+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030856///regulation of epithelial cell differentiation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031175///neuron projection development+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0032886///regulation of microtubule-based process+++GO:0033077///T cell differentiation in thymus+++GO:0035019///somatic stem cell population maintenance+++GO:0042483///negative regulation of odontogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043409///negative regulation of MAPK cascade+++GO:0043588///skin development+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0044337///canonical Wnt signaling pathway involved in positive regulation of apoptotic process+++GO:0045595///regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0046716///muscle cell cellular homeostasis+++GO:0048538///thymus development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051171///regulation of nitrogen compound metabolic process+++GO:0051276///chromosome organization+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0060041///retina development in camera-type eye+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0065003///protein-containing complex assembly+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1904781///positive regulation of protein localization to centrosome+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000211///regulation of glutamate metabolic process 11790 11790 'Speg' mRNA 620 549 409 14.79 12.28 10.49 9.87 11.34 10.72 12.52 10.64333333 378 434 386 526 399.3333333 0.008878398 -0.401382898 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001701///in utero embryonic development+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0042692///muscle cell differentiation+++GO:0055013///cardiac muscle cell development+++GO:0060541///respiratory system development+++GO:0072359///circulatory system development 117903916 117903916 'Gm16286' mRNA 852.29 880.2 883.93 29.96 30.51 32.97 37.26 37.87 35.34 31.14666667 36.82333333 1217.79 1208.01 1117.51 872.14 1181.103333 4.38E-06 0.424896331 GO:0031415///NatA complex GO:0008080///N-acetyltransferase activity+++GO:1990189///peptide-serine-N-acetyltransferase activity+++GO:1990190///peptide-glutamate-N-acetyltransferase activity GO:0017198///N-terminal peptidyl-serine acetylation+++GO:0018002///N-terminal peptidyl-glutamic acid acetylation 11792 11792 'Apex1' mRNA 548 639 558 25.34 29.17 27.38 39.8 38.61 34.78 27.29666667 37.73 988 935 835 581.6666667 919.3333333 1.21E-09 0.649098059 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0016607///nuclear speck+++GO:0048471///perinuclear region of cytoplasm "GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004527///exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008309///double-stranded DNA exodeoxyribonuclease activity+++GO:0008311///double-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016491///oxidoreductase activity+++GO:0016787///hydrolase activity+++GO:0016890///site-specific endodeoxyribonuclease activity, specific for altered base+++GO:0031490///chromatin DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0052720///class II DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0090580///phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands" "GO:0000723///telomere maintenance+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007568///aging+++GO:0010243///response to organonitrogen compound+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0043488///regulation of mRNA stability+++GO:0045454///cell redox homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071320///cellular response to cAMP+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071417///cellular response to organonitrogen compound+++GO:0080111///DNA demethylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0097698///telomere maintenance via base-excision repair+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle" 11793 11793 'Atg5' mRNA 683 739 729 17.11 18.84 19.8 24.49 27.55 25.29 18.58333333 25.77666667 1121 1165 1098 717 1128 1.85E-11 0.641418589 04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04216///Ferroptosis+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0034045///phagophore assembly site membrane+++GO:0034274///Atg12-Atg5-Atg16 complex+++GO:0044233///Mitochondria-associated ER Membrane GO:0005515///protein binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0001974///blood vessel remodeling+++GO:0002376///immune system process+++GO:0002718///regulation of cytokine production involved in immune response+++GO:0006501///C-terminal protein lipidation+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006995///cellular response to nitrogen starvation+++GO:0009267///cellular response to starvation+++GO:0009410///response to xenobiotic stimulus+++GO:0009620///response to fungus+++GO:0016236///macroautophagy+++GO:0019883///antigen processing and presentation of endogenous antigen+++GO:0031397///negative regulation of protein ubiquitination+++GO:0035973///aggrephagy+++GO:0039689///negative stranded viral RNA replication+++GO:0042311///vasodilation+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043687///post-translational protein modification+++GO:0044804///autophagy of nucleus+++GO:0045060///negative thymic T cell selection+++GO:0048840///otolith development+++GO:0050765///negative regulation of phagocytosis+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060047///heart contraction+++GO:0060548///negative regulation of cell death+++GO:0061684///chaperone-mediated autophagy+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0070257///positive regulation of mucus secretion+++GO:0071500///cellular response to nitrosative stress+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:1902017///regulation of cilium assembly+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000619///negative regulation of histone H4-K16 acetylation 117934532 117934532 'Gm48552' mRNA 78 70 57 4.78 4.24 3.71 2.3 1.86 2.27 4.243333333 2.143333333 43 34 41 68.33333333 39.33333333 0.022597832 -0.805654281 GO:0016020///membrane+++GO:0016021///integral component of membrane 11796 11796 'Birc3' mRNA 289 333 341 5.77 6.4 7.24 17.34 15.25 16.93 6.47 16.50666667 997.52 847 950.53 321 931.6833333 4.57E-38 1.521834254 01524///Platinum drug resistance+++04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04668///TNF signaling pathway+++05132///Salmonella infection+++05145///Toxoplasmosis+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0031398///positive regulation of protein ubiquitination+++GO:0042326///negative regulation of phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0060544///regulation of necroptotic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070266///necroptotic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1902916///positive regulation of protein polyubiquitination+++GO:2000378///negative regulation of reactive oxygen species metabolic process 11797 11797 'Birc2' mRNA 1107 1159 1183 16.82 17.54 19.02 15.97 15.02 14.79 17.79333333 15.26 1227.48 1131 1118.47 1149.666667 1158.983333 0.988201161 -0.002804071 01524///Platinum drug resistance+++04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04668///TNF signaling pathway+++05132///Salmonella infection+++05145///Toxoplasmosis+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05222///Small cell lung cancer GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0035631///CD40 receptor complex+++GO:0045121///membrane raft GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051087///chaperone binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0098770///FBXO family protein binding "GO:0000209///protein polyubiquitination+++GO:0001666///response to hypoxia+++GO:0001890///placenta development+++GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0042326///negative regulation of phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045471///response to ethanol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051591///response to cAMP+++GO:0051726///regulation of cell cycle+++GO:0060544///regulation of necroptotic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070266///necroptotic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1902443///negative regulation of ripoptosome assembly involved in necroptotic process+++GO:1902523///positive regulation of protein K63-linked ubiquitination+++GO:1902524///positive regulation of protein K48-linked ubiquitination+++GO:1902527///positive regulation of protein monoubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 11798 11798 'Xiap' mRNA 2410.11 2392.2 2155.49 7.69 7.95 7.2 7.7 6.86 7.28 7.613333333 7.28 2489.05 2203.43 2306.81 2319.266667 2333.096667 0.983461196 -0.002595479 01524///Platinum drug resistance+++04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04510///Focal adhesion+++04621///NOD-like receptor signaling pathway+++05145///Toxoplasmosis+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005876///spindle microtubule+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097110///scaffold protein binding GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902530///positive regulation of protein linear polyubiquitination+++GO:1990001///inhibition of cysteine-type endopeptidase activity involved in apoptotic process 11799 11799 'Birc5' mRNA 31.63 26.47 20.87 1.69 1.13 1.16 28.41 30.43 30.88 1.326666667 29.90666667 549.36 564.07 567.19 26.32333333 560.2066667 1.21E-95 4.438706195 01524///Platinum drug resistance+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04390///Hippo signaling pathway+++05161///Hepatitis B+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer "GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0016324///apical plasma membrane+++GO:0030496///midbody+++GO:0031021///interphase microtubule organizing center+++GO:0032133///chromosome passenger complex+++GO:0032991///protein-containing complex" GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0019899///enzyme binding+++GO:0030414///peptidase inhibitor activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding "GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0000281///mitotic cytokinesis+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007346///regulation of mitotic cell cycle+++GO:0009790///embryo development+++GO:0010466///negative regulation of peptidase activity+++GO:0031503///protein-containing complex localization+++GO:0031536///positive regulation of exit from mitosis+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0051303///establishment of chromosome localization+++GO:0051726///regulation of cell cycle+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0061469///regulation of type B pancreatic cell proliferation" 11800 11800 'Api5' mRNA 2315 2391 2175 33.5 34.03 33.37 39.06 35.5 37.32 33.63333333 37.29333333 3108 2758 2876 2293.666667 2914 3.63E-07 0.333734539 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003723///RNA binding+++GO:0017134///fibroblast growth factor binding GO:0006915///apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:2000270///negative regulation of fibroblast apoptotic process 11801 11801 'Cd5l' mRNA 0 1 0 0 0.03 0 0.7 1.62 1.55 0.01 1.29 29 65 62 0.333333333 52 5.89E-08 7.176686099 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0030449///regulation of complement activation+++GO:0031638///zymogen activation+++GO:1903661///positive regulation of complement-dependent cytotoxicity 11803 11803 'Aplp1' mRNA 699 710 463 16.34 16.35 11.48 3.68 4.52 4.79 14.72333333 4.33 181 217 228 624 208.6666667 1.01E-22 -1.581703225 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0031695///alpha-2B adrenergic receptor binding+++GO:0031696///alpha-2C adrenergic receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding GO:0006378///mRNA polyadenylation+++GO:0006417///regulation of translation+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030900///forebrain development+++GO:0071874///cellular response to norepinephrine stimulus+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 11804 11804 'Aplp2' mRNA 16085 16784 16833 243.26 249.72 269.7 239.99 232.33 231.95 254.2266667 234.7566667 18377 17418 17203 16567.33333 17666 0.231006806 0.078867306 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding GO:0001967///suckling behavior+++GO:0006878///cellular copper ion homeostasis+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0007617///mating behavior+++GO:0007626///locomotory behavior+++GO:0008203///cholesterol metabolic process+++GO:0009790///embryo development+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030198///extracellular matrix organization+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0043393///regulation of protein binding+++GO:0050885///neuromuscular process controlling balance 11806 11806 'Apoa1' mRNA 9 9 17 0.58 0.58 1.17 0.51 0.35 0.35 0.776666667 0.403333333 9 6 6 11.66666667 7 0.425801777 -0.767193989 03320///PPAR signaling pathway+++04975///Fat digestion and absorption+++04977///Vitamin digestion and absorption+++04979///Cholesterol metabolism+++05143///African trypanosomiasis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0034365///discoidal high-density lipoprotein particle+++GO:0034366///spherical high-density lipoprotein particle+++GO:0042627///chylomicron GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031210///phosphatidylcholine binding+++GO:0034190///apolipoprotein receptor binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0042802///identical protein binding+++GO:0045499///chemorepellent activity+++GO:0055102///lipase inhibitor activity+++GO:0060228///phosphatidylcholine-sterol O-acyltransferase activator activity+++GO:0070653///high-density lipoprotein particle receptor binding+++GO:0071813///lipoprotein particle binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0001932///regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0002719///negative regulation of cytokine production involved in immune response+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006869///lipid transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008104///protein localization+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008211///glucocorticoid metabolic process+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0010903///negative regulation of very-low-density lipoprotein particle remodeling+++GO:0015914///phospholipid transport+++GO:0018158///protein oxidation+++GO:0018206///peptidyl-methionine modification+++GO:0019915///lipid storage+++GO:0030300///regulation of intestinal cholesterol absorption+++GO:0030301///cholesterol transport+++GO:0030325///adrenal gland development+++GO:0031100///animal organ regeneration+++GO:0031103///axon regeneration+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042632///cholesterol homeostasis+++GO:0043534///blood vessel endothelial cell migration+++GO:0043691///reverse cholesterol transport+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050821///protein stabilization+++GO:0050919///negative chemotaxis+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0051180///vitamin transport+++GO:0051345///positive regulation of hydrolase activity+++GO:0051346///negative regulation of hydrolase activity+++GO:0051347///positive regulation of transferase activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0055091///phospholipid homeostasis+++GO:0060192///negative regulation of lipase activity+++GO:0060354///negative regulation of cell adhesion molecule production+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070328///triglyceride homeostasis+++GO:0070508///cholesterol import+++GO:0120009///intermembrane lipid transfer+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902995///positive regulation of phospholipid efflux 11807 11807 'Apoa2' mRNA 1 4 1 0.08 0.3 0.08 1.17 0.32 1.2 0.153333333 0.896666667 9 3 10 2 7.333333333 0.171819695 1.871644249 03320///PPAR signaling pathway+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0034366///spherical high-density lipoprotein particle+++GO:0042627///chylomicron GO:0005102///signaling receptor binding+++GO:0005319///lipid transporter activity+++GO:0005543///phospholipid binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0031072///heat shock protein binding+++GO:0031210///phosphatidylcholine binding+++GO:0034190///apolipoprotein receptor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0055102///lipase inhibitor activity+++GO:0060228///phosphatidylcholine-sterol O-acyltransferase activator activity+++GO:0070653///high-density lipoprotein particle receptor binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0002719///negative regulation of cytokine production involved in immune response+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006869///lipid transport+++GO:0008203///cholesterol metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0009749///response to glucose+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010903///negative regulation of very-low-density lipoprotein particle remodeling+++GO:0018158///protein oxidation+++GO:0018206///peptidyl-methionine modification+++GO:0030300///regulation of intestinal cholesterol absorption+++GO:0030301///cholesterol transport+++GO:0031100///animal organ regeneration+++GO:0031647///regulation of protein stability+++GO:0032375///negative regulation of cholesterol transport+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034370///triglyceride-rich lipoprotein particle remodeling+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034384///high-density lipoprotein particle clearance+++GO:0042157///lipoprotein metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0046340///diacylglycerol catabolic process+++GO:0050766///positive regulation of phagocytosis+++GO:0050821///protein stabilization+++GO:0050995///negative regulation of lipid catabolic process+++GO:0050996///positive regulation of lipid catabolic process+++GO:0060192///negative regulation of lipase activity+++GO:0060621///negative regulation of cholesterol import+++GO:0060695///negative regulation of cholesterol transporter activity+++GO:0120009///intermembrane lipid transfer 11808 11808 'Apoa4' mRNA 437 375 366 15.27 12.92 13.57 11.31 11.15 11.91 13.92 11.45666667 372 358 379 392.6666667 369.6666667 0.564508028 -0.097860293 04975///Fat digestion and absorption+++04977///Vitamin digestion and absorption+++04979///Cholesterol metabolism+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0042627///chylomicron+++GO:0045202///synapse GO:0005507///copper ion binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0016209///antioxidant activity+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0060228///phosphatidylcholine-sterol O-acyltransferase activator activity+++GO:0120020///intermembrane cholesterol transfer activity GO:0002227///innate immune response in mucosa+++GO:0006695///cholesterol biosynthetic process+++GO:0006869///lipid transport+++GO:0006982///response to lipid hydroperoxide+++GO:0007159///leukocyte cell-cell adhesion+++GO:0008203///cholesterol metabolic process+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0016042///lipid catabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030300///regulation of intestinal cholesterol absorption+++GO:0032374///regulation of cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034445///negative regulation of plasma lipoprotein oxidation+++GO:0035634///response to stilbenoid+++GO:0042157///lipoprotein metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043691///reverse cholesterol transport+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0055088///lipid homeostasis+++GO:0065005///protein-lipid complex assembly+++GO:0070328///triglyceride homeostasis+++GO:0120009///intermembrane lipid transfer 11810 11810 'Apobec1' mRNA 432 437 482 9.89 9.49 11.82 58.38 56.38 59.24 10.4 58 3090 2825 2990 450.3333333 2968.333333 4.01E-218 2.706082138 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003824///catalytic activity+++GO:0004126///cytidine deaminase activity+++GO:0004131///cytosine deaminase activity+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0006641///triglyceride metabolic process+++GO:0006970///response to osmotic stress+++GO:0009410///response to xenobiotic stimulus+++GO:0009972///cytidine deamination+++GO:0010043///response to zinc ion+++GO:0010332///response to gamma radiation+++GO:0016554///cytidine to uridine editing+++GO:0016556///mRNA modification+++GO:0032869///cellular response to insulin stimulus+++GO:0042127///regulation of cell proliferation+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042493///response to drug+++GO:0042953///lipoprotein transport+++GO:0045471///response to ethanol+++GO:0048255///mRNA stabilization+++GO:0050790///regulation of catalytic activity+++GO:0051592///response to calcium ion+++GO:0051607///defense response to virus+++GO:0070383///DNA cytosine deamination+++GO:0080111///DNA demethylation+++GO:0090209///negative regulation of triglyceride metabolic process+++GO:0090310///negative regulation of methylation-dependent chromatin silencing+++GO:0090366///positive regulation of mRNA modification 11811 11811 'Apobec2' mRNA 129 141 128 6.49 7 6.83 6.7 6.06 7.7 6.773333333 6.82 153 135 170 132.6666667 152.6666667 0.44979472 0.191108567 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004126///cytidine deaminase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0009972///cytidine deamination+++GO:0016554///cytidine to uridine editing+++GO:0016556///mRNA modification+++GO:0080111///DNA demethylation 11812 11812 'Apoc1' mRNA 243 293 310 52.74 64.16 71.74 47.95 51.03 53.68 62.88 50.88666667 251 257 268 282 258.6666667 0.498653683 -0.139376785 04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle GO:0004859///phospholipase inhibitor activity+++GO:0005504///fatty acid binding+++GO:0055102///lipase inhibitor activity GO:0006641///triglyceride metabolic process+++GO:0006869///lipid transport+++GO:0008203///cholesterol metabolic process+++GO:0010900///negative regulation of phosphatidylcholine catabolic process+++GO:0010916///negative regulation of very-low-density lipoprotein particle clearance+++GO:0032375///negative regulation of cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034369///plasma lipoprotein particle remodeling+++GO:0034382///chylomicron remnant clearance+++GO:0034447///very-low-density lipoprotein particle clearance+++GO:0042157///lipoprotein metabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0045833///negative regulation of lipid metabolic process+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051005///negative regulation of lipoprotein lipase activity 11813 11813 'Apoc2' mRNA 13 9 18 1.26 0.87 1.88 76.49 80.55 75.5 1.336666667 77.51333333 841 878.59 789.72 13.33333333 836.4366667 6.78E-117 5.958193158 04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0034366///spherical high-density lipoprotein particle+++GO:0042627///chylomicron GO:0008047///enzyme activator activity+++GO:0008289///lipid binding+++GO:0016004///phospholipase activator activity+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0055102///lipase inhibitor activity+++GO:0060230///lipoprotein lipase activator activity GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0010518///positive regulation of phospholipase activity+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0010916///negative regulation of very-low-density lipoprotein particle clearance+++GO:0016042///lipid catabolic process+++GO:0032375///negative regulation of cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034382///chylomicron remnant clearance+++GO:0034384///high-density lipoprotein particle clearance+++GO:0042953///lipoprotein transport+++GO:0043086///negative regulation of catalytic activity+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045833///negative regulation of lipid metabolic process+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0050790///regulation of catalytic activity+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0060697///positive regulation of phospholipid catabolic process+++GO:0070328///triglyceride homeostasis 11814 11814 'Apoc3' mRNA 0 0 2 0 0 0.42 0 0 0.18 0.14 0.06 0 0 1 0.666666667 0.333333333 0.863090843 -0.975320503 03320///PPAR signaling pathway+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0034361///very-low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034366///spherical high-density lipoprotein particle+++GO:0042627///chylomicron GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0030234///enzyme regulator activity+++GO:0055102///lipase inhibitor activity+++GO:0070653///high-density lipoprotein particle receptor binding GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006642///triglyceride mobilization+++GO:0006869///lipid transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008203///cholesterol metabolic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0010903///negative regulation of very-low-density lipoprotein particle remodeling+++GO:0010916///negative regulation of very-low-density lipoprotein particle clearance+++GO:0010987///negative regulation of high-density lipoprotein particle clearance+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034382///chylomicron remnant clearance+++GO:0042157///lipoprotein metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0042953///lipoprotein transport+++GO:0043434///response to peptide hormone+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0045833///negative regulation of lipid metabolic process+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0060621///negative regulation of cholesterol import+++GO:0070328///triglyceride homeostasis+++GO:0071333///cellular response to glucose stimulus+++GO:0090324///negative regulation of oxidative phosphorylation 11815 11815 'Apod' mRNA 220941 223225 215159 6076.67 6049.2 6278.25 13930.49 14692.04 14408.49 6134.706667 14343.67333 583257 600468.23 583956.01 219775 589227.08 1.08E-192 1.411272924 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0022626///cytosolic ribosome+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0008289///lipid binding+++GO:0015485///cholesterol binding GO:0000302///response to reactive oxygen species+++GO:0006006///glucose metabolic process+++GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0007420///brain development+++GO:0007568///aging+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0014012///peripheral nervous system axon regeneration+++GO:0042246///tissue regeneration+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048678///response to axon injury+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0060588///negative regulation of lipoprotein lipid oxidation+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:2000098///negative regulation of smooth muscle cell-matrix adhesion+++GO:2000405///negative regulation of T cell migration 11816 11816 'Apoe' mRNA 120880 121227 119220 5907.07 5851.98 6182.35 10510.05 10922.12 10531.77 5980.466667 10654.64667 246569 250432 239419 120442.3333 245473.3333 1.00E-93 1.015036089 04979///Cholesterol metabolism+++05010///Alzheimer disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0034365///discoidal high-density lipoprotein particle+++GO:0042627///chylomicron+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:1990777///lipoprotein particle GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008201///heparin binding+++GO:0008289///lipid binding+++GO:0016209///antioxidant activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0046848///hydroxyapatite binding+++GO:0046911///metal chelating activity+++GO:0046983///protein dimerization activity+++GO:0048156///tau protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0060228///phosphatidylcholine-sterol O-acyltransferase activator activity+++GO:0070326///very-low-density lipoprotein particle receptor binding+++GO:0071813///lipoprotein particle binding+++GO:0120020///intermembrane cholesterol transfer activity "GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002021///response to dietary excess+++GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006707///cholesterol catabolic process+++GO:0006869///lipid transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006898///receptor-mediated endocytosis+++GO:0006979///response to oxidative stress+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007568///aging+++GO:0007616///long-term memory+++GO:0008104///protein localization+++GO:0008203///cholesterol metabolic process+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010544///negative regulation of platelet activation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010877///lipid transport involved in lipid storage+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0015909///long-chain fatty acid transport+++GO:0017038///protein import+++GO:0019068///virion assembly+++GO:0019934///cGMP-mediated signaling+++GO:0030195///negative regulation of blood coagulation+++GO:0031103///axon regeneration+++GO:0031175///neuron projection development+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0032805///positive regulation of low-density lipoprotein particle receptor catabolic process+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034382///chylomicron remnant clearance+++GO:0034384///high-density lipoprotein particle clearance+++GO:0034447///very-low-density lipoprotein particle clearance+++GO:0035641///locomotory exploration behavior+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042159///lipoprotein catabolic process+++GO:0042311///vasodilation+++GO:0042632///cholesterol homeostasis+++GO:0042981///regulation of apoptotic process+++GO:0042982///amyloid precursor protein metabolic process+++GO:0043254///regulation of protein complex assembly+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043691///reverse cholesterol transport+++GO:0044794///positive regulation by host of viral process+++GO:0045088///regulation of innate immune response+++GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0045773///positive regulation of axon extension+++GO:0045807///positive regulation of endocytosis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048844///artery morphogenesis+++GO:0050709///negative regulation of protein secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050807///regulation of synapse organization+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051246///regulation of protein metabolic process+++GO:0051651///maintenance of location in cell+++GO:0055088///lipid homeostasis+++GO:0055089///fatty acid homeostasis+++GO:0060999///positive regulation of dendritic spine development+++GO:0061000///negative regulation of dendritic spine development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0061771///response to caloric restriction+++GO:0070328///triglyceride homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071830///triglyceride-rich lipoprotein particle clearance+++GO:0071831///intermediate-density lipoprotein particle clearance+++GO:0072359///circulatory system development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090181///regulation of cholesterol metabolic process+++GO:0090207///regulation of triglyceride metabolic process+++GO:0090209///negative regulation of triglyceride metabolic process+++GO:0090370///negative regulation of cholesterol efflux+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:0097113///AMPA glutamate receptor clustering+++GO:0097114///NMDA glutamate receptor clustering+++GO:0098869///cellular oxidant detoxification+++GO:0120009///intermembrane lipid transfer+++GO:1900221///regulation of amyloid-beta clearance+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1901627///negative regulation of postsynaptic membrane organization+++GO:1901631///positive regulation of presynaptic membrane organization+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902947///regulation of tau-protein kinase activity+++GO:1902951///negative regulation of dendritic spine maintenance+++GO:1902952///positive regulation of dendritic spine maintenance+++GO:1902991///regulation of amyloid precursor protein catabolic process+++GO:1902995///positive regulation of phospholipid efflux+++GO:1902998///positive regulation of neurofibrillary tangle assembly+++GO:1902999///negative regulation of phospholipid efflux+++GO:1903001///negative regulation of lipid transport across blood brain barrier+++GO:1903002///positive regulation of lipid transport across blood brain barrier+++GO:1905855///positive regulation of heparan sulfate binding+++GO:1905860///positive regulation of heparan sulfate proteoglycan binding+++GO:1905890///regulation of cellular response to very-low-density lipoprotein particle stimulus+++GO:1905906///regulation of amyloid fibril formation+++GO:1905907///negative regulation of amyloid fibril formation+++GO:2000822///regulation of behavioral fear response" 11818 11818 'Apoh' mRNA 6 6 8 0.37 0.31 0.47 0.14 0.46 0.69 0.383333333 0.43 3 10 14 6.666666667 9 0.733678173 0.422760076 04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0042627///chylomicron GO:0005543///phospholipid binding+++GO:0008201///heparin binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0060230///lipoprotein lipase activator activity "GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006641///triglyceride metabolic process+++GO:0007596///blood coagulation+++GO:0007597///blood coagulation, intrinsic pathway+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0016525///negative regulation of angiogenesis+++GO:0030193///regulation of blood coagulation+++GO:0030195///negative regulation of blood coagulation+++GO:0031100///animal organ regeneration+++GO:0031639///plasminogen activation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0034197///triglyceride transport+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0051917///regulation of fibrinolysis+++GO:0051918///negative regulation of fibrinolysis+++GO:0060268///negative regulation of respiratory burst" 11819 11819 'Nr2f2' mRNA 708 722 715 9.13 9.08 9.91 9.57 8.25 9.78 9.373333333 9.2 834 697 819 715 783.3333333 0.340918218 0.118085526 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001972///retinoic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001893///maternal placenta development+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001945///lymph vessel development+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0008585///female gonad development+++GO:0009566///fertilization+++GO:0009952///anterior/posterior pattern specification+++GO:0009956///radial pattern formation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0030900///forebrain development+++GO:0032355///response to estradiol+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0048856///anatomical structure development+++GO:0060173///limb development+++GO:0060674///placenta blood vessel development+++GO:0060707///trophoblast giant cell differentiation+++GO:0060838///lymphatic endothelial cell fate commitment" 11820 11820 'App' mRNA 17148.32 17233.99 11864.56 279.94 276.46 204.8 166.9 193.61 190.02 253.7333333 183.51 11805 13267 13037 15415.62333 12703 0.095405058 -0.281117751 04726///Serotonergic synapse+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0035253///ciliary rootlet+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043235///receptor complex+++GO:0044297///cell body+++GO:0044304///main axon+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0051233///spindle midzone+++GO:0055037///recycling endosome+++GO:0070381///endosome to plasma membrane transport vesicle+++GO:0097449///astrocyte projection+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0106003///amyloid-beta complex+++GO:1990761///growth cone lamellipodium+++GO:1990777///lipoprotein particle+++GO:1990812///growth cone filopodium GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003682///chromatin binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005158///insulin receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0016504///peptidase activator activity+++GO:0019899///enzyme binding+++GO:0030414///peptidase inhibitor activity+++GO:0030546///receptor activator activity+++GO:0033130///acetylcholine receptor binding+++GO:0034185///apolipoprotein binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding+++GO:0046875///ephrin receptor binding+++GO:0046914///transition metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0050786///RAGE receptor binding+++GO:0051087///chaperone binding+++GO:0051425///PTB domain binding+++GO:0070851///growth factor receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000185///activation of MAPKKK activity+++GO:0000187///activation of MAPK activity+++GO:0001774///microglial cell activation+++GO:0001878///response to yeast+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001967///suckling behavior+++GO:0002265///astrocyte activation involved in immune response+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006378///mRNA polyadenylation+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006878///cellular copper ion homeostasis+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007155///cell adhesion+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007617///mating behavior+++GO:0007626///locomotory behavior+++GO:0008088///axo-dendritic transport+++GO:0008203///cholesterol metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0009314///response to radiation+++GO:0009987///cellular process+++GO:0010288///response to lead ion+++GO:0010466///negative regulation of peptidase activity+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0014005///microglia development+++GO:0016199///axon midline choice point recognition+++GO:0016322///neuron remodeling+++GO:0016358///dendrite development+++GO:0019722///calcium-mediated signaling+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0030198///extracellular matrix organization+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0032092///positive regulation of protein binding+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0035066///positive regulation of histone acetylation+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0040014///regulation of multicellular organism growth+++GO:0042327///positive regulation of phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043393///regulation of protein binding+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045821///positive regulation of glycolytic process+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0048143///astrocyte activation+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048669///collateral sprouting in absence of injury+++GO:0050729///positive regulation of inflammatory response+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050803///regulation of synapse structure or activity+++GO:0050808///synapse organization+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050885///neuromuscular process controlling balance+++GO:0050890///cognition+++GO:0050918///positive chemotaxis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0051247///positive regulation of protein metabolic process+++GO:0051260///protein homooligomerization+++GO:0051262///protein tetramerization+++GO:0051402///neuron apoptotic process+++GO:0051563///smooth endoplasmic reticulum calcium ion homeostasis+++GO:0060291///long-term synaptic potentiation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0061903///positive regulation of 1-phosphatidylinositol-3-kinase activity+++GO:0070206///protein trimerization+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070555///response to interleukin-1+++GO:0071280///cellular response to copper ion+++GO:0071287///cellular response to manganese ion+++GO:0071320///cellular response to cAMP+++GO:0071874///cellular response to norepinephrine stimulus+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090647///modulation of age-related behavioral decline+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0150003///regulation of spontaneous synaptic transmission+++GO:1900122///positive regulation of receptor binding+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1900221///regulation of amyloid-beta clearance+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:1902950///regulation of dendritic spine maintenance+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903048///regulation of acetylcholine-gated cation channel activity+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:1903523///negative regulation of blood circulation+++GO:1904022///positive regulation of G protein-coupled receptor internalization+++GO:1904472///positive regulation of endothelin secretion+++GO:1904591///positive regulation of protein import+++GO:1904646///cellular response to amyloid-beta+++GO:1905606///regulation of presynapse assembly+++GO:1905893///positive regulation of cellular response to thapsigargin+++GO:1905896///positive regulation of cellular response to tunicamycin+++GO:1905898///positive regulation of response to endoplasmic reticulum stress+++GO:1905906///regulation of amyloid fibril formation+++GO:1905908///positive regulation of amyloid fibril formation+++GO:1905945///regulation of response to calcium ion+++GO:1990000///amyloid fibril formation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990535///neuron projection maintenance+++GO:2000406///positive regulation of T cell migration+++GO:2000463///positive regulation of excitatory postsynaptic potential 11821 11821 'Aprt' mRNA 798 869 748 61.24 66.05 60.92 156.4 149.41 157.14 62.73666667 154.3166667 2334 2172 2265 805 2257 3.88E-86 1.476937056 00230///Purine metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0002055///adenine binding+++GO:0003999///adenine phosphoribosyltransferase activity+++GO:0016208///AMP binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006166///purine ribonucleoside salvage+++GO:0006168///adenine salvage+++GO:0007595///lactation+++GO:0007625///grooming behavior+++GO:0009116///nucleoside metabolic process+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0032869///cellular response to insulin stimulus+++GO:0044209///AMP salvage+++GO:0046083///adenine metabolic process 11826 11826 'Aqp1' mRNA 710 727 521 14.22 14.33 11.07 85.38 73.68 76.89 13.20666667 78.65 4905 4134 4277 652.6666667 4438.666667 3.00E-208 2.758069159 04924///Renin secretion+++04964///Proximal tubule bicarbonate reclamation+++04976///Bile secretion GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0020003///symbiont-containing vacuole+++GO:0020005///symbiont-containing vacuole membrane+++GO:0030424///axon+++GO:0031526///brush border membrane+++GO:0031965///nuclear membrane+++GO:0032127///dense core granule membrane+++GO:0032809///neuronal cell body membrane+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043679///axon terminus+++GO:0045177///apical part of cell+++GO:0070062///extracellular exosome GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0005267///potassium channel activity+++GO:0005372///water transmembrane transporter activity+++GO:0008519///ammonium transmembrane transporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015168///glycerol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015267///channel activity+++GO:0022857///transmembrane transporter activity+++GO:0030184///nitric oxide transmembrane transporter activity+++GO:0035379///carbon dioxide transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046875///ephrin receptor binding GO:0003094///glomerular filtration+++GO:0003097///renal water transport+++GO:0006813///potassium ion transport+++GO:0006833///water transport+++GO:0006884///cell volume homeostasis+++GO:0006972///hyperosmotic response+++GO:0009725///response to hormone+++GO:0009992///cellular water homeostasis+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010634///positive regulation of epithelial cell migration+++GO:0015670///carbon dioxide transport+++GO:0015696///ammonium transport+++GO:0015793///glycerol transport+++GO:0019233///sensory perception of pain+++GO:0019725///cellular homeostasis+++GO:0019934///cGMP-mediated signaling+++GO:0021670///lateral ventricle development+++GO:0030104///water homeostasis+++GO:0030185///nitric oxide transport+++GO:0030335///positive regulation of cell migration+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0032940///secretion by cell+++GO:0033363///secretory granule organization+++GO:0034220///ion transmembrane transport+++GO:0034644///cellular response to UV+++GO:0035377///transepithelial water transport+++GO:0035378///carbon dioxide transmembrane transport+++GO:0042060///wound healing+++GO:0042538///hyperosmotic salinity response+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043627///response to estrogen+++GO:0044241///lipid digestion+++GO:0045766///positive regulation of angiogenesis+++GO:0046878///positive regulation of saliva secretion+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048593///camera-type eye morphogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051458///corticotropin secretion+++GO:0055085///transmembrane transport+++GO:0070295///renal water absorption+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071241///cellular response to inorganic substance+++GO:0071260///cellular response to mechanical stimulus+++GO:0071280///cellular response to copper ion+++GO:0071288///cellular response to mercury ion+++GO:0071300///cellular response to retinoic acid+++GO:0071320///cellular response to cAMP+++GO:0071456///cellular response to hypoxia+++GO:0071472///cellular response to salt stress+++GO:0071474///cellular hyperosmotic response+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0071805///potassium ion transmembrane transport+++GO:0072220///metanephric descending thin limb development+++GO:0072230///metanephric proximal straight tubule development+++GO:0072232///metanephric proximal convoluted tubule segment 2 development+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072488///ammonium transmembrane transport+++GO:0085018///maintenance of symbiont-containing vacuole by host+++GO:0098655///cation transmembrane transport 11827 11827 'Aqp2' mRNA 5 5 12 0.21 0.21 0.54 1.14 0.75 0.64 0.32 0.843333333 31 20 17 7.333333333 22.66666667 0.028388718 1.595280604 04962///Vasopressin-regulated water reabsorption GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030133///transport vesicle+++GO:0030136///clathrin-coated vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031303///integral component of endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0070382///exocytic vesicle+++GO:0098576///lumenal side of membrane GO:0003779///actin binding+++GO:0005372///water transmembrane transporter activity+++GO:0015168///glycerol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015267///channel activity+++GO:0030165///PDZ domain binding GO:0003091///renal water homeostasis+++GO:0003097///renal water transport+++GO:0006833///water transport+++GO:0006884///cell volume homeostasis+++GO:0006915///apoptotic process+++GO:0015793///glycerol transport+++GO:0030042///actin filament depolymerization+++GO:0042631///cellular response to water deprivation+++GO:0051289///protein homotetramerization+++GO:0051928///positive regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0071280///cellular response to copper ion+++GO:0071288///cellular response to mercury ion+++GO:0072205///metanephric collecting duct development 11828 11828 'Aqp3' mRNA 2 5 1 0.07 0.16 0.03 0.2 0.23 0.27 0.086666667 0.233333333 7 8 9 2.666666667 8 0.196928523 1.591972073 04962///Vasopressin-regulated water reabsorption GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0015204///urea transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015254///glycerol channel activity+++GO:0015267///channel activity+++GO:0042802///identical protein binding GO:0002684///positive regulation of immune system process+++GO:0006833///water transport+++GO:0015793///glycerol transport+++GO:0015840///urea transport+++GO:0032526///response to retinoic acid+++GO:0042476///odontogenesis+++GO:0055085///transmembrane transport+++GO:0070295///renal water absorption+++GO:0071456///cellular response to hypoxia+++GO:0071918///urea transmembrane transport+++GO:0090650///cellular response to oxygen-glucose deprivation 11829 11829 'Aqp4' mRNA 677 639 714 6.89 6.39 7.72 3.98 3.38 3.84 7 3.733333333 449 374 419 676.6666667 414 4.42E-09 -0.724730237 04962///Vasopressin-regulated water reabsorption+++04976///Bile secretion GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030315///T-tubule+++GO:0031253///cell projection membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0097450///astrocyte end-foot GO:0005515///protein binding+++GO:0015250///water channel activity+++GO:0015267///channel activity+++GO:0042802///identical protein binding GO:0006833///water transport+++GO:0007605///sensory perception of sound+++GO:0009992///cellular water homeostasis+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0015670///carbon dioxide transport+++GO:0030104///water homeostasis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033326///cerebrospinal fluid secretion+++GO:0050891///multicellular organismal water homeostasis+++GO:0051289///protein homotetramerization+++GO:0055085///transmembrane transport+++GO:0060354///negative regulation of cell adhesion molecule production+++GO:0070295///renal water absorption+++GO:0071333///cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0090660///cerebrospinal fluid circulation+++GO:0098609///cell-cell adhesion 11830 11830 'Aqp5' mRNA 20 17 10 0.76 0.64 0.4 1.58 1.18 0.99 0.6 1.25 48 35 29 15.66666667 37.33333333 0.017895812 1.246347208 04970///Salivary secretion GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0015250///water channel activity+++GO:0015267///channel activity+++GO:0042802///identical protein binding GO:0006833///water transport+++GO:0015670///carbon dioxide transport+++GO:0030157///pancreatic juice secretion+++GO:0042476///odontogenesis+++GO:0046541///saliva secretion+++GO:0048593///camera-type eye morphogenesis+++GO:0051289///protein homotetramerization+++GO:0055085///transmembrane transport+++GO:0071476///cellular hypotonic response 11831 11831 'Aqp6' mRNA 12 10 6 0.17 0.2 0.11 0.04 0.05 0.02 0.16 0.036666667 2 6 2 9.333333333 3.333333333 0.192146451 -1.480040958 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0015112///nitrate transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015267///channel activity GO:0006833///water transport+++GO:0015670///carbon dioxide transport+++GO:0015706///nitrate transport+++GO:0042476///odontogenesis+++GO:0055085///transmembrane transport 11832 11832 'Aqp7' mRNA 26.77 28.3 21.72 0.63 0.96 0.71 0.18 0.42 0.36 0.766666667 0.32 8.61 20.06 16.9 25.59666667 15.19 0.233396288 -0.770195457 03320///PPAR signaling pathway+++04923///Regulation of lipolysis in adipocytes GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:1990904///ribonucleoprotein complex GO:0015204///urea transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015254///glycerol channel activity+++GO:0015265///urea channel activity+++GO:0015267///channel activity GO:0006833///water transport+++GO:0015793///glycerol transport+++GO:0015840///urea transport+++GO:0055085///transmembrane transport+++GO:0070295///renal water absorption+++GO:0071918///urea transmembrane transport 11833 11833 'Aqp8' mRNA 0 2 0 0 0.08 0 0.14 0.07 0.11 0.026666667 0.106666667 4 2 3 0.666666667 3 0.353503855 2.179856186 04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0046691///intracellular canaliculus GO:0015250///water channel activity+++GO:0015267///channel activity GO:0006833///water transport+++GO:0015722///canalicular bile acid transport+++GO:0055085///transmembrane transport+++GO:0071320///cellular response to cAMP 11834 11834 'Aqr' mRNA 807 755 762 8.83 8.11 8.83 8.44 8.15 8.13 8.59 8.24 888 840 828 774.6666667 852 0.258937451 0.124780574 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0034458///3'-5' RNA helicase activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 11835 11835 'Ar' mRNA 138 103 114 0.72 0.53 0.63 0.15 0.16 0.13 0.626666667 0.146666667 33 34 27 118.3333333 31.33333333 2.31E-10 -1.929333751 04114///Oocyte meiosis+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001091///RNA polymerase II basal transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005496///steroid binding+++GO:0005497///androgen binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0032553///ribonucleotide binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051117///ATPase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070974///POU domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0003382///epithelial cell morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007620///copulation+++GO:0008049///male courtship behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0009987///cellular process+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0014734///skeletal muscle hypertrophy+++GO:0019098///reproductive behavior+++GO:0019102///male somatic sex determination+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0030521///androgen receptor signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0033327///Leydig cell differentiation+++GO:0035264///multicellular organism growth+++GO:0042327///positive regulation of phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045597///positive regulation of cell differentiation+++GO:0045720///negative regulation of integrin biosynthetic process+++GO:0045726///positive regulation of integrin biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0046661///male sex differentiation+++GO:0048608///reproductive structure development+++GO:0048638///regulation of developmental growth+++GO:0048645///animal organ formation+++GO:0048808///male genitalia morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060406///positive regulation of penile erection+++GO:0060520///activation of prostate induction by androgen receptor signaling pathway+++GO:0060571///morphogenesis of an epithelial fold+++GO:0060599///lateral sprouting involved in mammary gland duct morphogenesis+++GO:0060685///regulation of prostatic bud formation+++GO:0060736///prostate gland growth+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0060749///mammary gland alveolus development+++GO:0060769///positive regulation of epithelial cell proliferation involved in prostate gland development+++GO:0061458///reproductive system development+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0072520///seminiferous tubule development+++GO:1903076///regulation of protein localization to plasma membrane+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 11836 11836 'Araf' mRNA 4113 4265 4158 100.11 101.73 110.01 75.06 71.22 71.29 103.95 72.52333333 3425 3176 3145 4178.666667 3248.666667 2.21E-09 -0.376218257 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04068///FoxO signaling pathway+++04270///Vascular smooth muscle contraction+++04650///Natural killer cell mediated cytotoxicity+++04720///Long-term potentiation+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04928///Parathyroid hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0032006///regulation of TOR signaling+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process 11837 11837 'Rplp0' mRNA 9083 8977 8621 400.9 391.01 403.7 645.15 600.69 651.96 398.5366667 632.6 16784 15245 16405 8893.666667 16144.66667 1.65E-63 0.847904927 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0030425///dendrite+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:1990904///ribonucleoprotein complex GO:0003735///structural constituent of ribosome+++GO:0042277///peptide binding+++GO:0070180///large ribosomal subunit rRNA binding GO:0000027///ribosomal large subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0042254///ribosome biogenesis+++GO:0071353///cellular response to interleukin-4 11838 11838 'Arc' mRNA 52 67 40 0.93 1.18 0.76 1.9 2.06 1.72 0.956666667 1.893333333 122 129 107 53 119.3333333 3.90E-05 1.166490495 05031///Amphetamine addiction GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0098839///postsynaptic density membrane+++GO:0098845///postsynaptic endosome+++GO:0098978///glutamatergic synapse+++GO:1903561///extracellular vesicle GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003779///actin binding+++GO:0005515///protein binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0009952///anterior/posterior pattern specification+++GO:0016477///cell migration+++GO:0022604///regulation of cell morphogenesis+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051028///mRNA transport+++GO:0051260///protein homooligomerization+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0110077///vesicle-mediated intercellular transport+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1900452///regulation of long-term synaptic depression+++GO:2000969///positive regulation of AMPA receptor activity 11839 11839 'Areg' mRNA 1 0 1 0.05 0 0.05 0.44 0.23 0.36 0.033333333 0.343333333 10 5 8 0.666666667 7.666666667 0.029881154 3.498654126 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04151///PI3K-Akt signaling pathway+++04390///Hippo signaling pathway+++05210///Colorectal cancer GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0034704///calcium channel complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990246///uniplex complex GO:0005125///cytokine activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019855///calcium channel inhibitor activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0014009///glial cell proliferation+++GO:0014070///response to organic cyclic compound+++GO:0031175///neuron projection development+++GO:0032355///response to estradiol+++GO:0036444///calcium import into the mitochondrion+++GO:0042327///positive regulation of phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0043434///response to peptide hormone+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051384///response to glucocorticoid+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051591///response to cAMP+++GO:0060598///dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060749///mammary gland alveolus development+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation 11840 11840 'Arf1' mRNA 11645 12530 11542 371.75 394.53 390.9 440.56 449.58 440.86 385.7266667 443.6666667 15838 15788 15351 11905.66667 15659 6.07E-14 0.384092926 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05110///Vibrio cholerae infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005778///peroxisomal membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030054///cell junction+++GO:0030137///COPI-coated vesicle+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:1990583///phospholipase D activator activity GO:0002090///regulation of receptor internalization+++GO:0006878///cellular copper ion homeostasis+++GO:0006886///intracellular protein transport+++GO:0007015///actin filament organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0045807///positive regulation of endocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0050714///positive regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0055108///Golgi to transport vesicle transport+++GO:0060292///long-term synaptic depression+++GO:0060999///positive regulation of dendritic spine development+++GO:0070142///synaptic vesicle budding+++GO:0097061///dendritic spine organization+++GO:0097212///lysosomal membrane organization+++GO:0098586///cellular response to virus+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1902307///positive regulation of sodium ion transmembrane transport+++GO:1902824///positive regulation of late endosome to lysosome transport+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport+++GO:1903725///regulation of phospholipid metabolic process+++GO:1990386///mitotic cleavage furrow ingression 11841 11841 'Arf2' mRNA 1172 1087 1149 28.92 26.37 30.08 33.72 32.48 32.81 28.45666667 33.00333333 1577 1481 1477 1136 1511.666667 3.15E-06 0.398612809 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05110///Vibrio cholerae infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019904///protein domain specific binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 11842 11842 'Arf3' mRNA 2722.43 2625.09 2258.02 42.46 40.24 37.39 33.15 27.57 30.74 40.03 30.48666667 2445.14 1985 2195 2535.18 2208.38 0.012796937 -0.209534677 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport" 11843 11843 'Arf4' mRNA 4350 4451 4197 149.65 150.95 153.18 238.54 233.83 236.22 151.26 236.1966667 7968 7623 7635 4332.666667 7742 3.43E-58 0.825744279 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032587///ruffle membrane+++GO:0043197///dendritic spine+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0006471///protein ADP-ribosylation+++GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007420///brain development+++GO:0007612///learning+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016477///cell migration+++GO:0031584///activation of phospholipase D activity+++GO:0043066///negative regulation of apoptotic process+++GO:0045176///apical protein localization+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048678///response to axon injury+++GO:0050807///regulation of synapse organization+++GO:0060996///dendritic spine development+++GO:0061512///protein localization to cilium+++GO:0099175///regulation of postsynapse organization+++GO:2000377///regulation of reactive oxygen species metabolic process" 11844 11844 'Arf5' mRNA 2291 2225 1071 134.42 129.03 66.67 90.13 103.73 105.84 110.04 99.9 1762 1977 2000 1862.333333 1913 0.918503569 0.044633911 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport" 118445 118445 'Klf16' mRNA 109 86 92 2.28 1.77 2.04 1.74 1.53 1.82 2.03 1.696666667 96 82 97 95.66666667 91.66666667 0.844074409 -0.074323044 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007212///dopamine receptor signaling pathway 118446 118446 'Gjc3' mRNA 1159.46 1096.84 865.78 17.54 16.32 13.89 18.03 17.48 18.22 15.91666667 17.91 1371.67 1299.25 1342.2 1040.693333 1337.706667 2.37E-04 0.355545039 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043209///myelin sheath GO:0005243///gap junction channel activity+++GO:0042802///identical protein binding GO:0000902///cell morphogenesis+++GO:0002088///lens development in camera-type eye+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007605///sensory perception of sound+++GO:0035265///organ growth+++GO:0042552///myelination+++GO:0055085///transmembrane transport 118449 118449 'Synpo2' mRNA 292 276 260 2.26 2.11 2.13 0.96 0.73 0.92 2.166666667 0.87 140 101 128 276 123 1.48E-10 -1.178738457 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle+++GO:0099023///tethering complex "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0031005///filamin binding+++GO:0051371///muscle alpha-actinin binding+++GO:0051393///alpha-actinin binding+++GO:0071889///14-3-3 protein binding" GO:0000045///autophagosome assembly+++GO:0030335///positive regulation of cell migration+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0061684///chaperone-mediated autophagy+++GO:2000298///regulation of Rho-dependent protein serine/threonine kinase activity 11845 11845 'Arf6' mRNA 399 381 158 5.79 5.44 2.43 3.07 3.02 3.95 4.553333333 3.346666667 243 234 303 312.6666667 260 0.372043466 -0.259888157 04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031527///filopodium membrane+++GO:0031901///early endosome membrane+++GO:0032154///cleavage furrow+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0090543///Flemming body+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0031996///thioesterase binding+++GO:0047485///protein N-terminus binding GO:0001889///liver development+++GO:0006886///intracellular protein transport+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0010975///regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030154///cell differentiation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032456///endocytic recycling+++GO:0033028///myeloid cell apoptotic process+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0034394///protein localization to cell surface+++GO:0035020///regulation of Rac protein signal transduction+++GO:0036010///protein localization to endosome+++GO:0048488///synaptic vesicle endocytosis+++GO:0050714///positive regulation of protein secretion+++GO:0051301///cell division+++GO:0051489///regulation of filopodium assembly+++GO:0051549///positive regulation of keratinocyte migration+++GO:0060998///regulation of dendritic spine development+++GO:0090162///establishment of epithelial cell polarity+++GO:0097178///ruffle assembly+++GO:0097284///hepatocyte apoptotic process+++GO:0099562///maintenance of postsynaptic density structure+++GO:0120183///positive regulation of focal adhesion disassembly+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905606///regulation of presynapse assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2000171///negative regulation of dendrite development 118451 118451 'Mrps2' mRNA 620 621 586 16.86 16.64 16.89 16.34 16.33 17.89 16.79666667 16.85333333 693 674 737 609 701.3333333 0.089378925 0.192542771 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0061668///mitochondrial ribosome assembly 118452 118452 'Baalc' mRNA 327.67 274.28 326.72 1.98 1.64 2.09 2.37 2.78 2.7 1.903333333 2.616666667 414.62 472.05 462.1 309.5566667 449.59 4.77E-04 0.52688872 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0003674///molecular_function GO:0008150///biological_process 118453 118453 'Mmp28' mRNA 91.53 108.39 99.39 2.6 2.69 2.76 1.68 1.69 1.47 2.683333333 1.613333333 65.66 72.9 61.22 99.77 66.59333333 0.036499754 -0.60096672 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process 118454 118454 'Gjc2' mRNA 25 24 29 0.62 0.61 0.77 0.62 0.6 0.84 0.666666667 0.686666667 30 26 37 26 31 0.696860755 0.237680397 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0033270///paranode region of axon+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:1990769///proximal neuron projection GO:0005243///gap junction channel activity+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling GO:0001932///regulation of protein phosphorylation+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007420///brain development+++GO:0009636///response to toxic substance+++GO:0010628///positive regulation of gene expression+++GO:0010644///cell communication by electrical coupling+++GO:0055085///transmembrane transport+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:1904427///positive regulation of calcium ion transmembrane transport+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 11846 11846 'Arg1' mRNA 33 47 53 1.32 1.86 2.25 96.74 96.9 96.87 1.81 96.83666667 2771 2708 2684 44.33333333 2721 0 5.927594125 00220///Arginine biosynthesis+++00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids+++05146///Amoebiasis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body "GO:0004053///arginase activity+++GO:0016787///hydrolase activity+++GO:0016813///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0000050///urea cycle+++GO:0001889///liver development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006525///arginine metabolic process+++GO:0007568///aging+++GO:0009635///response to herbicide+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0010269///response to selenium ion+++GO:0010963///regulation of L-arginine import+++GO:0014075///response to amine+++GO:0019547///arginine catabolic process to ornithine+++GO:0030324///lung development+++GO:0032964///collagen biosynthetic process+++GO:0033189///response to vitamin A+++GO:0033197///response to vitamin E+++GO:0042130///negative regulation of T cell proliferation+++GO:0042493///response to drug+++GO:0042832///defense response to protozoan+++GO:0043200///response to amino acid+++GO:0045087///innate immune response+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0046686///response to cadmium ion+++GO:0048678///response to axon injury+++GO:0051597///response to methylmercury+++GO:0060056///mammary gland involution+++GO:0060135///maternal process involved in female pregnancy+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070965///positive regulation of neutrophil mediated killing of fungus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071353///cellular response to interleukin-4+++GO:0071377///cellular response to glucagon stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1905541///regulation of L-arginine import across plasma membrane+++GO:2000552///negative regulation of T-helper 2 cell cytokine production 11847 11847 'Arg2' mRNA 1351.74 1371.36 1389.27 56.87 56.93 62.01 52.22 51.9 48.38 58.60333333 50.83333333 1425.28 1382.21 1277.46 1370.79 1361.65 0.860584938 -0.02280249 00220///Arginine biosynthesis+++00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids+++05146///Amoebiasis GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0004053///arginase activity+++GO:0016787///hydrolase activity+++GO:0016813///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0050998///nitric-oxide synthase binding" "GO:0000050///urea cycle+++GO:0001657///ureteric bud development+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002829///negative regulation of type 2 immune response+++GO:0006525///arginine metabolic process+++GO:0006941///striated muscle contraction+++GO:0010963///regulation of L-arginine import+++GO:0019547///arginine catabolic process to ornithine+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032696///negative regulation of interleukin-13 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0045087///innate immune response+++GO:0045988///negative regulation of striated muscle contraction+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0071641///negative regulation of macrophage inflammatory protein 1 alpha production+++GO:0071644///negative regulation of chemokine (C-C motif) ligand 4 production+++GO:0071650///negative regulation of chemokine (C-C motif) ligand 5 production+++GO:1900425///negative regulation of defense response to bacterium+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1905403///negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process+++GO:1905541///regulation of L-arginine import across plasma membrane+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2000774///positive regulation of cellular senescence" 11848 11848 'Rhoa' mRNA 4846 4861 4365 130.16 127.32 124.92 232.35 203.91 223.28 127.4666667 219.8466667 9934 8546 9306 4690.666667 9262 9.72E-65 0.97018948 "04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04150///mTOR signaling pathway+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04361///Axon regeneration+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04611///Platelet activation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04972///Pancreatic secretion+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043296///apical junction complex+++GO:0071944///cell periphery+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0017022///myosin binding+++GO:0019003///GDP binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0051022///Rho GDP-dissociation inhibitor binding "GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0001998///angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0002363///alpha-beta T cell lineage commitment+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007229///integrin-mediated signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0007519///skeletal muscle tissue development+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0008360///regulation of cell shape+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009749///response to glucose+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010975///regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021795///cerebral cortex cell migration+++GO:0021861///forebrain radial glial cell differentiation+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030521///androgen receptor signaling pathway+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030865///cortical cytoskeleton organization+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032467///positive regulation of cytokinesis+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033144///negative regulation of intracellular steroid hormone receptor signaling pathway+++GO:0033688///regulation of osteoblast proliferation+++GO:0034329///cell junction assembly+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035385///Roundabout signaling pathway+++GO:0036089///cleavage furrow formation+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0042476///odontogenesis+++GO:0042493///response to drug+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043149///stress fiber assembly+++GO:0043200///response to amino acid+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043297///apical junction assembly+++GO:0043366///beta selection+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043542///endothelial cell migration+++GO:0043931///ossification involved in bone maturation+++GO:0044319///wound healing, spreading of cells+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045471///response to ethanol+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045727///positive regulation of translation+++GO:0045785///positive regulation of cell adhesion+++GO:0045792///negative regulation of cell size+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046039///GTP metabolic process+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0050773///regulation of dendrite development+++GO:0050919///negative chemotaxis+++GO:0051301///cell division+++GO:0051384///response to glucocorticoid+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051924///regulation of calcium ion transport+++GO:0060193///positive regulation of lipase activity+++GO:0060548///negative regulation of cell death+++GO:0061383///trabecula morphogenesis+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0071803///positive regulation of podosome assembly+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0090307///mitotic spindle assembly+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0097498///endothelial tube lumen extension+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902766///skeletal muscle satellite cell migration+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903673///mitotic cleavage furrow formation+++GO:1904695///positive regulation of vascular smooth muscle contraction+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1905244///regulation of modification of synaptic structure+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:1990869///cellular response to chemokine+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000406///positive regulation of T cell migration" 11852 11852 'Rhob' mRNA 445 476 131 10.61 11.18 3.31 6.59 9.43 11.91 8.366666667 9.31 318 444 556 350.6666667 439.3333333 0.654980456 0.342340728 05132///Salmonella infection GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0032154///cleavage furrow+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019901///protein kinase binding GO:0000281///mitotic cytokinesis+++GO:0001525///angiogenesis+++GO:0006886///intracellular protein transport+++GO:0006915///apoptotic process+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0008333///endosome to lysosome transport+++GO:0008360///regulation of cell shape+++GO:0010595///positive regulation of endothelial cell migration+++GO:0015031///protein transport+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043065///positive regulation of apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045786///negative regulation of cell cycle+++GO:0061154///endothelial tube morphogenesis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071479///cellular response to ionizing radiation 11853 11853 'Rhoc' mRNA 2982 2955 2941 178.07 174.36 186.28 284 293.88 292.26 179.57 290.0466667 5454 5501 5428 2959.333333 5461 2.58E-48 0.871731232 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding "GO:0000281///mitotic cytokinesis+++GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043297///apical junction assembly+++GO:0044319///wound healing, spreading of cells+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060193///positive regulation of lipase activity+++GO:1902766///skeletal muscle satellite cell migration" 11854 11854 'Rhod' mRNA 481 470 484 15.66 15.21 16.52 17.48 17.93 17.71 15.79666667 17.70666667 587 561 578 478.3333333 575.3333333 0.037838272 0.253376139 04360///Axon guidance GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0060342///photoreceptor inner segment membrane+++GO:0097225///sperm midpiece+++GO:0097381///photoreceptor disc membrane+++GO:1990913///sperm head plasma membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005502///11-cis retinal binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity+++GO:0016918///retinal binding+++GO:0019901///protein kinase binding+++GO:0030507///spectrin binding+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0006605///protein targeting+++GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0008360///regulation of cell shape+++GO:0009416///response to light stimulus+++GO:0009583///detection of light stimulus+++GO:0009585///red, far-red light phototransduction+++GO:0016038///absorption of visible light+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0016477///cell migration+++GO:0018298///protein-chromophore linkage+++GO:0030032///lamellipodium assembly+++GO:0030335///positive regulation of cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043052///thermotaxis+++GO:0045494///photoreceptor cell maintenance+++GO:0045785///positive regulation of cell adhesion+++GO:0048041///focal adhesion assembly+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus+++GO:0050960///detection of temperature stimulus involved in thermoception+++GO:0051017///actin filament bundle assembly+++GO:0051893///regulation of focal adhesion assembly+++GO:0060041///retina development in camera-type eye+++GO:0071482///cellular response to light stimulus+++GO:2000249///regulation of actin cytoskeleton reorganization" 11855 11855 'Arhgap5' mRNA 2479 2528 2192 18.58 18.81 17.66 14.53 12.67 14.02 18.35 13.74 2196 1943 2100 2399.666667 2079.666667 0.002609017 -0.216814595 04510///Focal adhesion+++04670///Leukocyte transendothelial migration GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005525///GTP binding+++GO:0042169///SH2 domain binding GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007165///signal transduction+++GO:0008361///regulation of cell size+++GO:0030335///positive regulation of cell migration+++GO:0030879///mammary gland development+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 11856 11856 'Arhgap6' mRNA 140 122 96 1.65 1.39 1.26 2.38 2.61 2.68 1.433333333 2.556666667 223 238 239 119.3333333 233.3333333 1.10E-06 0.961121305 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0005096///GTPase activator activity+++GO:0016004///phospholipase activator activity+++GO:0017124///SH3 domain binding+++GO:0043274///phospholipase binding GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0007202///activation of phospholipase C activity+++GO:0010518///positive regulation of phospholipase activity+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0048041///focal adhesion assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051895///negative regulation of focal adhesion assembly 118567331 118567331 'LOC118567331' mRNA 1.1 1.13 0 0.12 0.13 0 0.2 0 0.32 0.083333333 0.173333333 2.02 0 3.15 0.743333333 1.723333333 0.673209247 1.328444305 118567336 118567336 'LOC118567336' mRNA 76.31 75.04 49.75 0.26 0.26 0.18 0.54 0.4 0.48 0.233333333 0.473333333 177.88 129.53 155.71 67.03333333 154.3733333 2.86E-06 1.197440895 118567343 118567343 'LOC118567343' mRNA 15.54 24.81 8.23 0.55 1.1 0.37 0.38 0.31 0.13 0.673333333 0.273333333 10.31 9.62 3.99 16.19333333 7.973333333 0.215789489 -1.091826495 118567355 118567355 'LOC118567355' mRNA 1.08 4.01 3.43 0.06 0.22 0.21 0.17 0.06 0.31 0.163333333 0.18 3.53 1.1 6.1 2.84 3.576666667 0.866100837 0.306699659 118567363 118567363 'LOC118567363' mRNA 0 2 0 0 0.2 0 0 0 0 0.066666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0016020///membrane+++GO:0016021///integral component of membrane 118567373 118567373 'LOC118567373' mRNA 39 45 25 1.19 1.38 0.83 0.19 0 0.05 1.133333333 0.08 7 0 2 36.33333333 3 2.33E-06 -3.608641007 118567384 118567384 'LOC118567384' mRNA 8.13 5.03 3.48 0.87 0.53 0.4 2.26 1.91 1.32 0.6 1.83 24.18 19.88 13.61 5.546666667 19.22333333 0.023695151 1.80138943 118567385 118567385 'LOC118567385' mRNA 2 4 0 0.1 0.21 0 0.14 0.14 0.14 0.103333333 0.14 3 3 3 2 3 0.779936972 0.604199931 118567399 118567399 'LOC118567399' mRNA 6 7 4 0.54 0.71 0.39 0.09 0.15 0.09 0.546666667 0.11 2 2 1 5.666666667 1.666666667 0.229887723 -1.768632383 118567439 118567439 'LOC118567439' mRNA 231.7 245.47 145.62 5.69 5.94 3.8 1.05 0.79 0.95 5.143333333 0.93 49.18 36.08 42.99 207.5966667 42.75 1.65E-18 -2.293266847 118567440 118567440 'LOC118567440' mRNA 3.75 1.82 1.51 0.11 0.05 0.05 0 0 0 0.07 0 0 0 0 2.36 0 0.334169217 -3.181769893 118567464 118567464 'LOC118567464' mRNA 1.02 3.05 1.02 0.03 0.07 0.03 0.02 0.05 0 0.043333333 0.023333333 1.03 2.07 0 1.696666667 1.033333333 0.804321789 -0.728902625 118567466 118567466 'LOC118567466' mRNA 6.69 12.91 5.81 0.51 0.98 0.47 0.21 0.51 0.81 0.653333333 0.51 3.1 7.44 11.73 8.47 7.423333333 0.920153515 -0.124437805 118567479 118567479 'LOC118567479' mRNA 305.53 279.88 215.13 8.13 7.34 6.07 15.06 12.43 15.06 7.18 14.18333333 650.92 524.44 629.8 266.8466667 601.72 1.08E-16 1.165863025 118567481 118567481 'LOC118567481' mRNA 163.74 190.28 176.06 2.44 2.73 2.76 2.87 3.84 4.09 2.643333333 3.6 225.97 299.74 321 176.6933333 282.2366667 6.36E-04 0.666664039 118567495 118567495 'LOC118567495' mRNA 6.14 8.18 4.23 0.25 0.32 0.18 0.14 0.04 0 0.25 0.06 4.04 1.01 0 6.183333333 1.683333333 0.231006806 -1.86108282 118567505 118567505 'LOC118567505' mRNA 53.54 45.27 37.71 0.23 0.19 0.17 0.2 0.23 0.17 0.196666667 0.2 55.28 60.85 45.13 45.50666667 53.75333333 0.596473812 0.23805844 118567536 118567536 'LOC118567536' mRNA 0 1 0 0 0.14 0 0 0 0.25 0.046666667 0.083333333 0 0 1.99 0.333333333 0.663333333 0.998591786 -0.011756601 118567551 118567551 'LOC118567551' mRNA 311.47 339.05 321.32 3.94 4.22 4.32 0.87 0.75 0.9 4.16 0.84 78.98 66.56 79.5 323.9466667 75.01333333 1.83E-30 -2.135161772 118567557 118567557 'LOC118567557' mRNA 115.47 102.26 93.57 2.17 1.9 1.87 18.15 19.92 16.18 1.98 18.08333333 1108.94 1188.31 957.32 103.7666667 1084.856667 8.02E-130 3.381909164 118567621 118567621 'LOC118567621' mRNA 846.27 884.71 913.76 14.34 14.67 16.34 16.6 19.12 15.16 15.11666667 16.96 1120.73 1246.76 991.48 881.58 1119.656667 0.00342259 0.332083857 118567625 118567625 'LOC118567625' mRNA 20.5 21.83 23.02 1.62 1.71 1.93 2.08 2.75 1.68 1.753333333 2.17 30.14 38.85 23.52 21.78333333 30.83666667 0.388116407 0.494944647 118567631 118567631 'LOC118567631' mRNA 685.98 630.15 559.97 8.27 7.47 7.16 1.53 1.15 1.13 7.633333333 1.27 146.37 106.78 104.32 625.3666667 119.1566667 1.12E-55 -2.407531249 118567641 118567641 'LOC118567641' mRNA 857 865 640 8.99 8.92 7.12 3.76 4.29 4.66 8.343333333 4.236666667 413 460 496 787.3333333 456.3333333 4.01E-10 -0.791502777 118567643 118567643 'LOC118567643' mRNA 17 16 20 0.63 0.58 0.79 0.13 0.4 0.33 0.666666667 0.286666667 4 12 10 17.66666667 8.666666667 0.183260595 -1.037649682 118567658 118567658 'LOC118567658' mRNA 1.09 0 1.07 0.05 0 0.05 0 0.05 0 0.033333333 0.016666667 0 1.09 0 0.72 0.363333333 0.859375267 -0.929010473 118567664 118567664 'LOC118567664' mRNA 297.94 265.96 239.86 2.81 2.46 2.4 1.69 1.27 1.81 2.556666667 1.59 206.04 151.65 213.87 267.92 190.52 0.008081306 -0.501963934 118567759 118567759 'LOC118567759' mRNA 9.37 4.62 3.95 0.47 0.23 0.21 1.21 0.65 0.71 0.303333333 0.856666667 27.5 14.32 15.53 5.98 19.11666667 0.027549372 1.797438543 118567769 118567769 'LOC118567769' mRNA 41.08 22.84 31.98 1.09 0.6 0.9 1.77 1.83 1.1 0.863333333 1.566666667 76.3 77.14 45.88 31.96666667 66.44 0.009867449 1.060555164 118567777 118567777 'LOC118567777' mRNA 0 0 4 0 0 0.25 0 0 0 0.083333333 0 0 0 0 1.333333333 0 0.505221307 -2.942890013 118567798 118567798 'LOC118567798' mRNA 0.92 1.09 2.95 0.1 0.12 0.36 0.3 0.11 0.31 0.193333333 0.24 3 1.04 3 1.653333333 2.346666667 0.633004077 1.1812455 118567814 118567814 'LOC118567814' mRNA 72.22 76.8 45.45 0.83 0.86 0.55 0.33 0.26 0.35 0.746666667 0.313333333 32.9 25.22 33.92 64.82333333 30.68 0.004322023 -1.104166093 118567837 118567837 'LOC118567837' mRNA 63.46 54.75 48.1 1.46 1.24 1.18 2.55 2.16 2.83 1.293333333 2.513333333 127.24 105.08 136.78 55.43666667 123.0333333 2.46E-05 1.147130783 118567843 118567843 'LOC118567843' mRNA 155.45 155.62 139.35 4.05 4 3.86 4.27 5.09 3.45 3.97 4.27 188.13 218.97 147.37 150.14 184.8233333 0.21837068 0.291296027 118567871 118567871 'LOC118567871' mRNA 1546.09 1474.85 1264.87 8.88 8.32 7.7 5.77 4.71 5.53 8.3 5.336666667 1158.39 922.74 1075.47 1428.603333 1052.2 2.43E-06 -0.45168163 118567886 118567886 'LOC118567886' mRNA 4.02 3.01 0 0.23 0.17 0 0.13 0 0.1 0.133333333 0.076666667 2.59 0 2 2.343333333 1.53 0.763397384 -0.797144001 118567893 118567893 'LOC118567893' mRNA 102.66 61.35 108.74 2.52 1.49 2.84 2.38 2.02 2.04 2.283333333 2.146666667 111.27 92.12 92.35 90.91666667 98.58 0.804977458 0.100627105 118567918 118567918 'LOC118567918' mRNA 412.08 385.72 373.78 2.02 1.85 1.93 2.2 2.04 2.2 1.933333333 2.146666667 519.98 470.21 501.6 390.5266667 497.2633333 0.008093253 0.336988842 118567927 118567927 'LOC118567927' mRNA 48.56 57.04 64.53 0.79 0.91 1.11 0.51 0.28 0.5 0.936666667 0.43 36.6 19.31 34.55 56.71 30.15333333 0.024280388 -0.94529347 118567987 118567987 'LOC118567987' mRNA 22.11 28.36 14.29 0.37 0.47 0.26 0.16 0.19 0.17 0.366666667 0.173333333 10.89 12.34 11.16 21.58666667 11.46333333 0.161958519 -0.954784766 118567992 118567992 'LOC118567992' mRNA 27.85 19.82 18.33 0.26 0.18 0.18 0.12 0.29 0.18 0.206666667 0.196666667 15.36 35.42 21.79 22 24.19 0.857271999 0.147736344 118568006 118568006 'LOC118568006' mRNA 11 8 17 0.33 0.24 0.54 0.18 0.11 0.05 0.37 0.113333333 7 4 2 12 4.333333333 0.130065048 -1.502204083 118568020 118568020 'LOC118568020' mRNA 50.54 50.58 53.77 0.78 0.77 0.88 0.6 0.44 0.44 0.81 0.493333333 44.61 31.93 31.96 51.63 36.16666667 0.191724533 -0.545972276 118568028 118568028 'LOC118568028' mRNA 6.29 6.37 1.88 0.27 0.27 0.08 0.19 0.17 0.14 0.206666667 0.166666667 5.05 4.4 3.64 4.846666667 4.363333333 0.949006166 -0.106629282 118568032 118568032 'LOC118568032' mRNA 1770.37 1764.55 1580.07 40.26 39.51 38.12 98.23 115.56 101.32 39.29666667 105.0366667 4968.6 5700.93 4961.44 1704.996667 5210.323333 1.65E-101 1.603075823 118568050 118568050 'LOC118568050' mRNA 219.2 228.71 185.44 1.28 1.32 1.15 1.06 0.73 0.93 1.25 0.906666667 207.61 140.08 176.86 211.1166667 174.85 0.189949658 -0.284324299 118568052 118568052 'LOC118568052' mRNA 21.59 19.61 23.04 0.57 0.51 0.65 0.37 0.5 0.66 0.576666667 0.51 16 21.07 27.64 21.41333333 21.57 0.996073497 0.009932163 118568062 118568062 'LOC118568062' mRNA 216.73 223.37 215.01 5.62 5.71 5.92 11.94 10.97 12.83 5.75 11.91333333 529.41 474.87 550.54 218.37 518.2733333 5.79E-20 1.235456703 118568072 118568072 'LOC118568072' mRNA 158.15 143.01 155.23 3.64 3.24 3.79 2.01 1.68 2.35 3.556666667 2.013333333 100.73 82.22 113.71 152.13 98.88666667 0.006973994 -0.642525441 118568080 118568080 'LOC118568080' mRNA 597.79 618.59 583.69 9.46 9.57 10.11 17.72 17.84 17.88 9.713333333 17.81333333 1327.53 1308.08 1298.55 600.0233333 1311.386667 9.12E-38 1.117884243 118568094 118568094 'LOC118568094' mRNA 144 151 174 0.68 0.7 0.87 0.47 0.5 0.55 0.75 0.506666667 115 119 130 156.3333333 121.3333333 0.110017128 -0.381008481 118568152 118568152 'LOC118568152' mRNA 465.32 479.15 500.91 7.48 7.58 8.54 20.24 18.68 18.31 7.866666667 19.07666667 1448.46 1306.24 1269.15 481.7933333 1341.283333 1.52E-50 1.463929326 118568183 118568183 'LOC118568183' mRNA 0 1.04 0 0 0.1 0 0.08 0 0 0.033333333 0.026666667 1 0 0 0.346666667 0.333333333 0.998591786 -0.011756601 118568219 118568219 'LOC118568219' mRNA 97.95 115.08 117 0.58 0.67 0.73 0.58 0.39 0.54 0.66 0.503333333 113.17 74.87 103.03 110.01 97.02333333 0.537039404 -0.198988638 118568241 118568241 'LOC118568241' mRNA 407.38 388.64 398.76 11.33 10.61 11.74 18.3 20.27 17.84 11.22666667 18.80333333 772.3 828.08 722.51 398.26 774.2966667 1.15E-16 0.948891972 118568243 118568243 'LOC118568243' mRNA 68 65 63.02 0.91 0.86 0.9 0.83 0.94 0.67 0.89 0.813333333 71 79 56 65.34 68.66666667 0.876322572 0.06092466 118568255 118568255 'LOC118568255' mRNA 5 2.93 2 0.13 0.07 0.06 0.02 0.02 0.02 0.086666667 0.02 1 1 1 3.31 1 0.44226547 -1.589439039 118568281 118568281 'LOC118568281' mRNA 11.87 7.18 9.94 0.36 0.23 0.34 0.18 0.2 0.29 0.31 0.223333333 6.28 7.04 11.1 9.663333333 8.14 0.863357859 -0.181380025 118568284 118568284 'LOC118568284' mRNA 190.38 185.39 187.65 6.06 5.82 6.34 3.6 3.06 3.61 6.073333333 3.423333333 130.04 107.83 125.94 187.8066667 121.27 0.001627597 -0.648189667 118568297 118568297 'LOC118568297' mRNA 355.7 323.25 289.58 11.37 10.18 9.82 4.89 5.6 4.2 10.45666667 4.896666667 175.9 196.48 146.02 322.8433333 172.8 1.27E-07 -0.912066132 118568299 118568299 'LOC118568299' mRNA 112.4 111.71 79.03 3.59 3.51 2.67 1.5 1.26 2.42 3.256666667 1.726666667 54.21 44.47 84.46 101.0466667 61.04666667 0.024800299 -0.735867923 118568300 118568300 'LOC118568300' mRNA 99.38 105.63 109.8 3.18 3.33 3.73 2.46 1.97 2.45 3.413333333 2.293333333 88.27 68.88 85.02 104.9366667 80.72333333 0.172828848 -0.392339033 118568301 118568301 'LOC118568301' mRNA 19.09 48.56 31.67 0.61 1.52 1.07 0.36 0.96 0.61 1.066666667 0.643333333 13.1 33.84 21.32 33.10666667 22.75333333 0.386291407 -0.549747522 118568304 118568304 'LOC118568304' mRNA 30.43 44.14 34.92 0.95 1.36 1.16 0.7 0.53 0.66 1.156666667 0.63 25.7 19.19 23.54 36.49666667 22.81 0.164355575 -0.700052697 118568306 118568306 'LOC118568306' mRNA 186.27 190.45 155.11 5.73 5.77 5.06 3.47 1.96 3.72 5.52 3.05 129.59 71.61 134.45 177.2766667 111.8833333 0.007730703 -0.680467586 118568307 118568307 'LOC118568307' mRNA 79.27 67.64 81.04 2.72 2.28 2.95 1.93 1.57 1.79 2.65 1.763333333 64.64 51.48 58.1 75.98333333 58.07333333 0.233372917 -0.408494188 118568308 118568308 'LOC118568308' mRNA 223.48 234.19 180.16 7.16 7.39 6.12 3.72 3.08 3.79 6.89 3.53 133.35 107.77 131.72 212.61 124.28 8.31E-05 -0.788435677 118568310 118568310 'LOC118568310' mRNA 177.2 145.6 155.15 5.55 4.49 5.15 2.44 2.18 2.74 5.063333333 2.453333333 89.71 78.27 97.26 159.3166667 88.41333333 1.93E-04 -0.866187325 118568311 118568311 'LOC118568311' mRNA 191.64 196.99 178.06 6.06 6.14 5.97 1.86 2.4 2.6 6.056666667 2.286666667 67.49 85.31 91.6 188.8966667 81.46666667 3.41E-08 -1.225980395 118568312 118568312 'LOC118568312' mRNA 18 15 19 0.64 0.53 0.72 0.56 0.57 0.71 0.63 0.613333333 18 18 22 17.33333333 19.33333333 0.863090843 0.142516593 118568322 118568322 'LOC118568322' mRNA 21 13 20 3.81 2.36 3.85 1.44 1.65 1.99 3.34 1.693333333 9 10 12 18 10.33333333 0.271629637 -0.816723614 118568335 118568335 'LOC118568335' mRNA 31 28 33 1.84 1.65 2.08 0.88 1.54 1.07 1.856666667 1.163333333 17 29 20 30.66666667 22 0.391045179 -0.490407014 118568337 118568337 'LOC118568337' mRNA 200.74 201 139.31 6.49 6.4 4.78 3.3 2.88 2.8 5.89 2.993333333 117.18 99.98 96.4 180.35 104.52 3.90E-04 -0.797665692 118568338 118568338 'LOC118568338' mRNA 2 9.74 14 0.07 0.3 0.5 0.32 0.1 0.06 0.29 0.16 11 3.38 2 8.58 5.46 0.610287477 -0.690014625 118568339 118568339 'LOC118568339' mRNA 63.89 78.54 59.97 2.02 2.44 2.01 1.27 0.81 0.91 2.156666667 0.996666667 46.15 28.65 32.04 67.46666667 35.61333333 0.01260694 -0.927688514 118568340 118568340 'LOC118568340' mRNA 88.68 107.23 84.56 2.8 3.34 2.84 2.54 1.52 1.26 2.993333333 1.773333333 92.4 53.84 44.49 93.49 63.57666667 0.096189486 -0.576131269 118568343 118568343 'LOC118568343' mRNA 298.97 245.04 262.78 9.5 7.68 8.86 4.16 5.31 4.01 8.68 4.493333333 150.4 187.35 140.3 268.93 159.35 6.31E-05 -0.765758539 118568345 118568345 'LOC118568345' mRNA 94.69 83.24 75.67 3.03 2.62 2.57 2.16 1.15 1.73 2.74 1.68 77.52 40.52 60.35 84.53333333 59.46333333 0.128974852 -0.523615128 118568348 118568348 'LOC118568348' mRNA 143.09 107.65 132.73 4.46 3.31 4.39 1.9 2.3 2.12 4.053333333 2.106666667 69.94 82.64 75.68 127.8233333 76.08666667 0.00369905 -0.770396711 118568354 118568354 'LOC118568354' mRNA 25.48 35.57 23.28 3.44 4.79 3.34 1.58 1.82 1.69 3.856666667 1.696666667 13.33 14.9 13.71 28.11 13.98 0.069108062 -1.058555844 118568368 118568368 'LOC118568368' mRNA 8 11 4 0.98 1.34 0.52 2.35 1.98 1.44 0.946666667 1.923333333 22 18 13 7.666666667 17.66666667 0.123520602 1.203223653 118568416 118568416 'LOC118568416' mRNA 881.14 839.98 782.37 26.39 24.79 24.85 54.12 47.03 54.35 25.34333333 51.83333333 2077.42 1762.17 2019.38 834.4966667 1952.99 6.54E-48 1.215598606 118568422 118568422 'LOC118568422' mRNA 2 0 0 0.09 0 0 0.08 0 0.04 0.03 0.04 2 0 1 0.666666667 1 0.876795627 0.578298478 118568424 118568424 'Akap17a' mRNA 2 0 1 0.03 0 0.02 0.02 0.05 0.05 0.016666667 0.04 1 3 3.03 1 2.343333333 0.621750124 1.21375884 118568432 118568432 'LOC118568432' mRNA 143.91 123.36 126.83 3.23 2.73 3.02 2.92 2.14 2.6 2.993333333 2.553333333 149.31 106.85 128.99 131.3666667 128.3833333 0.869607221 -0.047692273 118568448 118568448 'LOC118568448' mRNA 1.13 5.54 1.04 0.14 0.67 0.14 0.16 0.44 0 0.316666667 0.2 1.48 3.98 0 2.57 1.82 0.755958388 -0.787970185 118568452 118568452 'Rpa4' mRNA 13 20 5 0.09 0.14 0.04 0.27 0.15 0.25 0.09 0.223333333 44 24 40 12.66666667 36 0.010706354 1.508252088 118568468 118568468 'LOC118568468' mRNA 6.65 0 4.43 0.45 0 0.32 0.92 0.74 1.04 0.256666667 0.9 15.64 12.24 17.13 3.693333333 15.00333333 0.033280682 2.116173639 118568469 118568469 'LOC118568469' mRNA 0 1.22 0.37 0 0.18 0.06 0 0.13 0 0.08 0.043333333 0 0.99 0 0.53 0.33 0.863090843 -0.97353728 118568473 118568473 'LOC118568473' mRNA 1 0 0 0.08 0 0 0.11 0.07 0.04 0.026666667 0.073333333 1.58 1.05 0.52 0.333333333 1.05 0.863090843 0.881254164 118568475 118568475 'LOC118568475' mRNA 0 7.31 0 0 0.34 0 0.74 1.61 0.85 0.113333333 1.066666667 17.95 38.14 19.99 2.436666667 25.36 4.69E-04 3.421404802 118568482 118568482 'LOC118568482' mRNA 1 4.31 2 0.01 0.03 0.02 0 0.03 0.02 0.02 0.016666667 0 5 3 2.436666667 2.666666667 0.925309313 0.203517565 118568567 118568567 'LOC118568567' mRNA 39.76 48.01 39.94 0.24 0.29 0.26 0.08 0.14 0.12 0.263333333 0.113333333 16 26.01 22 42.57 21.33666667 0.036423681 -0.983431447 118568585 118568585 'LOC118568585' mRNA 3 1 2 0.17 0.05 0.12 0 0.05 0 0.113333333 0.016666667 0 1 0 2 0.333333333 0.37439817 -2.49639044 118568593 118568593 'LOC118568593' mRNA 425.38 398.14 237.49 7.87 7.23 4.64 3.81 2.97 2.92 6.58 3.233333333 237.14 181.76 176.83 353.67 198.5766667 3.75E-05 -0.838976825 118568594 118568594 'LOC118568594' mRNA 9.06 10.19 10 0.56 0.62 0.65 0.11 0.3 0.22 0.61 0.21 2 5.55 4 9.75 3.85 0.18775671 -1.406538336 118568607 118568607 'LOC118568607' mRNA 260.65 249.71 326.4 10.69 10.11 14.21 10.94 10.41 9.64 11.67 10.33 306.31 284.34 261.05 278.92 283.9 0.976593417 0.008297445 118568612 118568612 'LOC118568612' mRNA 2 4 0 0.14 0.28 0 0.06 0.32 0.06 0.14 0.146666667 1 5 1 2 2.333333333 0.911311124 0.255670084 118568627 118568627 'LOC118568627' mRNA 2 2 0 0.17 0.17 0 0 0 0 0.113333333 0 0 0 0 1.333333333 0 0.487988649 -2.833701114 118568632 118568632 'LOC118568632' mRNA 58.26 46.9 38.92 1.83 1.46 1.3 0.99 0.69 1.49 1.53 1.056666667 36.16 24.56 52.76 48.02666667 37.82666667 0.48305039 -0.350362055 118568634 118568634 'LOC118568634' mRNA 205.76 178.42 175.33 7.18 6.14 6.49 4.46 3.82 4.8 6.603333333 4.36 146.92 122.85 152.81 186.5033333 140.86 0.046640676 -0.421740194 118568637 118568637 'LOC118568637' mRNA 1 1 2 0.02 0.02 0.03 0.01 0 0 0.023333333 0.003333333 1 0 0 1.333333333 0.333333333 0.56881504 -1.924978749 118568644 118568644 'LOC118568644' mRNA 211.89 174.87 180.61 5.48 4.46 4.96 0.62 0.75 0.74 4.966666667 0.703333333 27.58 32.66 31.74 189.1233333 30.66 6.57E-24 -2.661034538 118568645 118568645 'LOC118568645' mRNA 1328.26 1136.25 1172.11 8.24 6.93 7.71 1.73 1.59 1.98 7.626666667 1.766666667 321.4 287.94 355.96 1212.206667 321.7666667 6.62E-66 -1.929094516 118568650 118568650 'LOC118568650' mRNA 3.09 4.21 1 0.14 0.18 0.05 0.04 0.04 0.04 0.123333333 0.04 1 1 1 2.766666667 1 0.524179931 -1.40619952 118568652 118568652 'LOC118568652' mRNA 13.02 13.84 6 0.26 0.23 0.08 1.6 1.07 1.29 0.19 1.32 75.21 52.63 69.71 10.95333333 65.85 1.26E-08 2.608749584 118568653 118568653 'LOC118568653' mRNA 1.94 4.16 0 0.09 0.19 0 0.3 0.23 0.42 0.093333333 0.316666667 7.52 5.57 10.09 2.033333333 7.726666667 0.1324418 2.150503249 118568662 118568662 'LOC118568662' mRNA 116.59 105.56 93.3 10.71 9.62 9.1 6.44 6.11 6.57 9.81 6.373333333 80.16 74.02 78.97 105.15 77.71666667 0.108142129 -0.446254707 118568683 118568683 'LOC118568683' mRNA 4762.45 4904.09 4540.31 64.62 65.37 64.52 96.97 97.66 93.52 64.83666667 96.05 8312.14 8104.66 7734.24 4735.616667 8050.346667 2.34E-46 0.754275687 118568702 118568702 'LOC118568702' mRNA 31 28 12 1.17 1.05 0.46 0.79 0.6 0.84 0.893333333 0.743333333 24 18 25 23.66666667 22.33333333 0.906281965 -0.082445613 118568705 118568705 'LOC118568705' mRNA 4015.18 4215.46 4245.77 99.43 103.01 111.56 200.39 205.82 193.23 104.6666667 199.8133333 9547.14 9540.71 8928.84 4158.803333 9338.896667 2.07E-75 1.153861827 118568709 118568709 'LOC118568709' mRNA 3 6 3 0.51 1.01 0.54 0 0.31 0 0.686666667 0.103333333 0 2 0 4 0.666666667 0.216550364 -2.573812634 118568718 118568718 'LOC118568718' mRNA 8040 7754 6496 814.31 779.81 698.28 544.19 448.72 533.65 764.1333333 508.8533333 6142 4928 5811 7430 5627 7.14E-08 -0.410764444 118568751 118568751 'LOC118568751' mRNA 36 35 20 0.67 0.64 0.39 0.37 0.45 0.65 0.566666667 0.49 23 27 39 30.33333333 29.66666667 0.962608227 -0.031751971 118568753 118568753 'LOC118568753' mRNA 119.4 125.59 79.36 1.38 1.42 0.97 0.68 0.62 0.89 1.256666667 0.73 68 60.46 86.21 108.1166667 71.55666667 0.046577641 -0.597544367 118568783 118568783 'LOC118568783' mRNA 3550.08 3459.33 3410.87 26.83 25.68 27.38 14.22 13.02 13.81 26.63 13.68333333 2145.33 1904.71 2017.75 3473.426667 2022.596667 1.34E-33 -0.793376113 118568792 118568792 'LOC118568792' mRNA 229.08 254.2 251.64 8.85 9.68 10.31 9.1 9.58 10.08 9.613333333 9.586666667 270.73 278.01 289.91 244.9733333 279.55 0.338107228 0.177057025 118568793 118568793 'LOC118568793' mRNA 13.96 12 3 0.26 0.22 0.06 0.15 0.15 0.08 0.18 0.126666667 9.03 8.9 4.96 9.653333333 7.63 0.740213982 -0.408019126 11857 11857 'Arhgdib' mRNA 307 301 350 15.97 15.57 19.39 170.78 164.14 163.76 16.97666667 166.2266667 3760 3521 3484 319.3333333 3588.333333 0 3.475566581 04722///Neurotrophin signaling pathway+++04962///Vasopressin-regulated water reabsorption GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005094///Rho GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0007266///Rho protein signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0071461///cellular response to redox state+++GO:1901164///negative regulation of trophoblast cell migration+++GO:2000249///regulation of actin cytoskeleton reorganization 11858 11858 'Rnd2' mRNA 2554 2446 2086 109.52 103.5 94.91 49.22 48.38 52.58 102.6433333 50.06 1318 1264 1362 2362 1314.666667 4.34E-29 -0.853938622 GO:0002080///acrosomal membrane+++GO:0005769///early endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0047485///protein N-terminus binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0048672///positive regulation of collateral sprouting 11859 11859 'Phox2a' mRNA 4 1 0 0.15 0.04 0 0.03 0.03 0.03 0.063333333 0.03 1 1 1 1.666666667 1 0.809813118 -0.722325179 GO:0000785///chromatin+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003357///noradrenergic neuron differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0021523///somatic motor neuron differentiation+++GO:0021623///oculomotor nerve formation+++GO:0021642///trochlear nerve formation+++GO:0021703///locus ceruleus development+++GO:0030901///midbrain development+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048484///enteric nervous system development+++GO:0048485///sympathetic nervous system development+++GO:0048486///parasympathetic nervous system development" 11861 11861 'Arl4a' mRNA 1126 1193 1012 16.65 17.34 15.89 8.32 9.22 8.63 16.62666667 8.723333333 647 701 650 1110.333333 666 2.81E-15 -0.746017577 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0050873///brown fat cell differentiation 11863 11863 'Arnt' mRNA 1424 1279 1440 17.58 15.53 18.98 18.22 15.88 15.7 17.36333333 16.6 1699 1441 1420 1381 1520 0.275513898 0.122241184 04066///HIF-1 signaling pathway+++04934///Cushing syndrome+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0034751///aryl hydrocarbon receptor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001666///response to hypoxia+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009636///response to toxic substance+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0033235///positive regulation of protein sumoylation+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046886///positive regulation of hormone biosynthetic process" 11864 11864 'Arnt2' mRNA 1096 1085 1057 9.66 9.42 9.92 12.33 11.98 11.2 9.666666667 11.83666667 1604 1528 1413 1079.333333 1515 1.04E-08 0.476877653 05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0034751///aryl hydrocarbon receptor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009636///response to toxic substance+++GO:0032355///response to estradiol+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 11865 11865 'Arntl' mRNA 559 579 590 8.38 8.78 10.38 5.54 4.74 5.4 9.18 5.226666667 398 343 383 576 374.6666667 2.91E-07 -0.634610566 04710///Circadian rhythm+++04711///Circadian rhythm - fly+++04728///Dopaminergic synapse GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0033391///chromatoid body+++GO:0034751///aryl hydrocarbon receptor complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0007283///spermatogenesis+++GO:0007623///circadian rhythm+++GO:0032007///negative regulation of TOR signaling+++GO:0032922///circadian regulation of gene expression+++GO:0042176///regulation of protein catabolic process+++GO:0042634///regulation of hair cycle+++GO:0042753///positive regulation of circadian rhythm+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis+++GO:0050796///regulation of insulin secretion+++GO:0051726///regulation of cell cycle+++GO:0051775///response to redox state+++GO:0060137///maternal process involved in parturition+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090403///oxidative stress-induced premature senescence+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901985///positive regulation of protein acetylation+++GO:2000074///regulation of type B pancreatic cell development+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway+++GO:2000772///regulation of cellular senescence+++GO:2001016///positive regulation of skeletal muscle cell differentiation" 11867 11867 'Arpc1b' mRNA 3480 3614 3352 131.93 135.11 134.81 577.11 612.35 584.75 133.95 591.4033333 17488.76 18107.97 17144 3482 17580.24333 0 2.325235809 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0015629///actin cytoskeleton+++GO:0036284///tubulobulbar complex GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0030833///regulation of actin filament polymerization+++GO:0032355///response to estradiol+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0043627///response to estrogen 11870 11870 'Art1' mRNA 953 839 878 40.51 35.1 39.43 4.06 4.36 3.97 38.34666667 4.13 109 113 103 890 108.3333333 3.19E-110 -3.050803608 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031225///anchored component of membrane+++GO:0033017///sarcoplasmic reticulum membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006471///protein ADP-ribosylation+++GO:0018120///peptidyl-arginine ADP-ribosylation 11872 11872 'Art2b' mRNA 0 2 1 0 0.03 0.01 0.11 0.06 0.02 0.013333333 0.063333333 10 5 2 1 5.666666667 0.144766852 2.484821443 00760///Nicotinate and nicotinamide metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0046658///anchored component of plasma membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003953///NAD+ nucleosidase activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0061810///NAD glycohydrolase activity" GO:0006471///protein ADP-ribosylation+++GO:0018120///peptidyl-arginine ADP-ribosylation+++GO:0019677///NAD catabolic process 11875 11875 'Art5' mRNA 73 60 69 2.51 1.96 2.47 1 0.95 1.64 2.313333333 1.196666667 34 31 50 67.33333333 38.33333333 0.026497269 -0.826203129 GO:0005576///extracellular region+++GO:0016020///membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003953///NAD+ nucleosidase activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006471///protein ADP-ribosylation+++GO:0018120///peptidyl-arginine ADP-ribosylation 11876 11876 'Artn' mRNA 280 297 304 6.66 6.88 7.83 1.36 1.17 0.97 7.123333333 1.166666667 67 57 45 293.6666667 56.33333333 3.18E-30 -2.397108172 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0030116///glial cell-derived neurotrophic factor receptor binding+++GO:0030971///receptor tyrosine kinase binding GO:0007166///cell surface receptor signaling pathway+++GO:0007411///axon guidance+++GO:0007422///peripheral nervous system development+++GO:0050930///induction of positive chemotaxis+++GO:0061146///Peyer's patch morphogenesis+++GO:0097021///lymphocyte migration into lymphoid organs 11877 11877 'Arvcf' mRNA 1631.47 1763.59 1669.13 21.24 22.79 23.2 10.17 10.48 10.6 22.41 10.41666667 853.52 877.92 912.6 1688.063333 881.3466667 4.63E-30 -0.949884621 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0045296///cadherin binding GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0098609///cell-cell adhesion 11881 11881 'Arsb' mRNA 990 1016 1022 13.4 13.53 14.67 23.96 23.7 24.71 13.86666667 24.12333333 2038 1969 2035 1009.333333 2014 4.90E-37 0.983845534 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface GO:0003824///catalytic activity+++GO:0003943///N-acetylgalactosamine-4-sulfatase activity+++GO:0004065///arylsulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006914///autophagy+++GO:0007417///central nervous system development+++GO:0007584///response to nutrient+++GO:0009268///response to pH+++GO:0010632///regulation of epithelial cell migration+++GO:0010976///positive regulation of neuron projection development+++GO:0043627///response to estrogen+++GO:0051597///response to methylmercury+++GO:0061580///colon epithelial cell migration+++GO:0097065///anterior head development 11883 11883 'Arsa' mRNA 992 997 935 15.46 15.28 15.45 15.66 16.31 14.79 15.39666667 15.58666667 1157 1177 1058 974.6666667 1130.666667 0.031637361 0.2031881 00600///Sphingolipid metabolism+++04142///Lysosome GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0031232///extrinsic component of external side of plasma membrane GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0004098///cerebroside-sulfatase activity+++GO:0005509///calcium ion binding+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006914///autophagy+++GO:0007339///binding of sperm to zona pellucida+++GO:0007417///central nervous system development+++GO:0007584///response to nutrient+++GO:0009268///response to pH+++GO:0043627///response to estrogen+++GO:0045471///response to ethanol+++GO:0051597///response to methylmercury 11886 11886 'Asah1' mRNA 2461.49 2732.81 2768.36 58.76 65 70.6 105.94 106.03 107.69 64.78666667 106.5533333 4949.64 4830.5 4877.57 2654.22 4885.903333 1.97E-33 0.866500284 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005764///lysosome "GO:0003714///transcription corepressor activity+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0016922///nuclear receptor binding+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0017064///fatty acid amide hydrolase activity+++GO:0102121///ceramidase activity" "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0010033///response to organic substance+++GO:0030216///keratinocyte differentiation+++GO:0030324///lung development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0046514///ceramide catabolic process+++GO:0050810///regulation of steroid biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:1903507///negative regulation of nucleic acid-templated transcription" 11889 11889 'Asgr1' mRNA 399 395 361 20.38 20.31 20.07 36.88 39.29 34.9 20.25333333 37.02333333 793 822 732 385 782.3333333 3.95E-20 1.012736748 04918///Thyroid hormone synthesis GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004873///asialoglycoprotein receptor activity+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0031668///cellular response to extracellular stimulus+++GO:0044419///interspecies interaction between organisms 11890 11890 'Asgr2' mRNA 3 9 9 0.13 0.44 0.42 0.69 0.67 1.01 0.33 0.79 19 17 24 7 20 0.046606161 1.497267578 04918///Thyroid hormone synthesis GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0048471///perinuclear region of cytoplasm GO:0030246///carbohydrate binding GO:0006897///endocytosis+++GO:0009100///glycoprotein metabolic process+++GO:0030282///bone mineralization+++GO:0031647///regulation of protein stability+++GO:0044419///interspecies interaction between organisms+++GO:0055088///lipid homeostasis 11891 11891 'Rab27a' mRNA 221 214 142 3.95 3.77 2.71 4.29 3.53 4.47 3.476666667 4.096666667 276.07 222 279 192.3333333 259.0233333 0.036478729 0.423870316 GO:0001750///photoreceptor outer segment+++GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0030667///secretory granule membrane+++GO:0032585///multivesicular body membrane+++GO:0033093///Weibel-Palade body+++GO:0042470///melanosome+++GO:0070382///exocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:0031489///myosin V binding GO:0006605///protein targeting+++GO:0006887///exocytosis+++GO:0007596///blood coagulation+++GO:0009306///protein secretion+++GO:0010628///positive regulation of gene expression+++GO:0016192///vesicle-mediated transport+++GO:0019882///antigen processing and presentation+++GO:0030318///melanocyte differentiation+++GO:0032400///melanosome localization+++GO:0032402///melanosome transport+++GO:0036257///multivesicular body organization+++GO:0043316///cytotoxic T cell degranulation+++GO:0043320///natural killer cell degranulation+++GO:0043473///pigmentation+++GO:0045921///positive regulation of exocytosis+++GO:0050766///positive regulation of phagocytosis+++GO:0051875///pigment granule localization+++GO:0051904///pigment granule transport+++GO:0071985///multivesicular body sorting pathway+++GO:0097278///complement-dependent cytotoxicity+++GO:1903307///positive regulation of regulated secretory pathway+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903435///positive regulation of constitutive secretory pathway+++GO:1990182///exosomal secretion 11898 11898 'Ass1' mRNA 738 784 732 26.42 27.67 27.8 37.63 43.38 44.62 27.29666667 41.87666667 1208 1359 1386 751.3333333 1317.666667 7.49E-17 0.80040229 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01230///Biosynthesis of amino acids+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0070852///cell body fiber GO:0000166///nucleotide binding+++GO:0004055///argininosuccinate synthase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015643///toxic substance binding+++GO:0016597///amino acid binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0000050///urea cycle+++GO:0000052///citrulline metabolic process+++GO:0000053///argininosuccinate metabolic process+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0006526///arginine biosynthetic process+++GO:0006531///aspartate metabolic process+++GO:0006953///acute-phase response+++GO:0007494///midgut development+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0007623///circadian rhythm+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009636///response to toxic substance+++GO:0010043///response to zinc ion+++GO:0010046///response to mycotoxin+++GO:0014075///response to amine+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0043434///response to peptide hormone+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0048545///response to steroid hormone+++GO:0051384///response to glucocorticoid+++GO:0060416///response to growth hormone+++GO:0060539///diaphragm development+++GO:0070542///response to fatty acid+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071242///cellular response to ammonium ion+++GO:0071320///cellular response to cAMP+++GO:0071346///cellular response to interferon-gamma+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071377///cellular response to glucagon stimulus+++GO:0071400///cellular response to oleic acid+++GO:0071418///cellular response to amine stimulus+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1903038///negative regulation of leukocyte cell-cell adhesion 11899 11899 'Astn1' mRNA 173.1 189.88 161.54 1.08 1.19 1.02 0.1 0.1 0.12 1.096666667 0.106666667 21.06 24.63 31.62 174.84 25.77 1.61E-23 -2.791468722 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043204///perikaryon GO:0005515///protein binding GO:0001764///neuron migration+++GO:0007155///cell adhesion+++GO:0007158///neuron cell-cell adhesion+++GO:0007626///locomotory behavior+++GO:0016477///cell migration+++GO:0098609///cell-cell adhesion 11905 11905 'Serpinc1' mRNA 1 2 2 0.04 0.07 0.08 0.07 0.07 0 0.063333333 0.046666667 2 2 0 1.666666667 1.333333333 0.892638561 -0.34134367 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008201///heparin binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding "GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0007584///response to nutrient+++GO:0007595///lactation+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030193///regulation of blood coagulation+++GO:2000266///regulation of blood coagulation, intrinsic pathway" 11906 11906 'Zfhx3' mRNA 2127 2093 1691 6.62 6.42 5.6 5.62 4.97 5.66 6.213333333 5.416666667 2004 1750 2002 1970.333333 1918.666667 0.674772868 -0.04675548 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007050///cell cycle arrest+++GO:0007420///brain development+++GO:0007517///muscle organ development+++GO:0032922///circadian regulation of gene expression+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0071559///response to transforming growth factor beta+++GO:1904059///regulation of locomotor rhythm" 11907 11907 'Ate1' mRNA 3177.29 3451.55 3198.77 55.12 58.22 59.76 34.65 38.29 37.2 57.7 36.71333333 2181.52 2289.06 2255.76 3275.87 2242.113333 2.37E-16 -0.558002137 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0004057///arginyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0010498///proteasomal protein catabolic process+++GO:0016598///protein arginylation 11908 11908 'Atf1' mRNA 512 558 543 12.23 13.14 13.79 17.5 17.09 18.4 13.05333333 17.66333333 844 801 853 537.6666667 832.6666667 2.86E-09 0.618407079 04925///Aldosterone synthesis and secretion+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:1990589///ATF4-CREB1 transcription factor complex+++GO:1990590///ATF1-ATF4 transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010976///positive regulation of neuron projection development+++GO:0014070///response to organic cyclic compound+++GO:0032025///response to cobalt ion+++GO:0034622///cellular protein-containing complex assembly+++GO:0045740///positive regulation of DNA replication+++GO:0045944///positive regulation of transcription by RNA polymerase II" 11909 11909 'Atf2' mRNA 1713 1656 1768.01 21.79 20.81 24.11 17.93 17.23 17.33 22.23666667 17.49666667 1613 1511 1534 1712.336667 1552.666667 0.081275072 -0.155528584 "04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04022///cGMP-PKG signaling pathway+++04151///PI3K-Akt signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04624///Toll and Imd signaling pathway+++04668///TNF signaling pathway+++04714///Thermogenesis+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016602///CCAAT-binding factor complex+++GO:0035861///site of double-strand break+++GO:1902562///H4 histone acetyltransferase complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008140///cAMP response element binding protein binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0019901///protein kinase binding+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043522///leucine zipper domain binding+++GO:0043565///sequence-specific DNA binding+++GO:0044013///H2B histone acetyltransferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001701///in utero embryonic development+++GO:0001865///NK T cell differentiation+++GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003151///outflow tract morphogenesis+++GO:0003360///brainstem development+++GO:0003418///growth plate cartilage chondrocyte differentiation+++GO:0003419///growth plate cartilage chondrocyte proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006915///apoptotic process+++GO:0006970///response to osmotic stress+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007033///vacuole organization+++GO:0007254///JNK cascade+++GO:0007507///heart development+++GO:0009414///response to water deprivation+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0016525///negative regulation of angiogenesis+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021742///abducens nucleus development+++GO:0021743///hypoglossal nucleus development+++GO:0021754///facial nucleus development+++GO:0030509///BMP signaling pathway+++GO:0031573///intra-S DNA damage checkpoint+++GO:0032915///positive regulation of transforming growth factor beta2 production+++GO:0034599///cellular response to oxidative stress+++GO:0038066///p38MAPK cascade+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0043969///histone H2B acetylation+++GO:0044255///cellular lipid metabolic process+++GO:0045444///fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050872///white fat cell differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060052///neurofilament cytoskeleton organization+++GO:0060245///detection of cell density+++GO:0060612///adipose tissue development+++GO:0072740///cellular response to anisomycin+++GO:0097049///motor neuron apoptotic process+++GO:0097186///amelogenesis+++GO:0097284///hepatocyte apoptotic process+++GO:0098586///cellular response to virus+++GO:0110024///positive regulation of cardiac muscle myoblast proliferation+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:1901976///regulation of cell cycle checkpoint+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902742///apoptotic process involved in development+++GO:1990144///intrinsic apoptotic signaling pathway in response to hypoxia+++GO:1990253///cellular response to leucine starvation" 11910 11910 'Atf3' mRNA 123 127 103 3.55 3.61 3.15 25.76 23.43 22.91 3.436666667 24.03333333 1027 912 884 117.6666667 941 3.05E-115 2.989114554 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:1990622///CHOP-ATF3 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006094///gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034198///cellular response to amino acid starvation+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1903984///positive regulation of TRAIL-activated apoptotic signaling pathway+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 11911 11911 'Atf4' mRNA 2227 2279 2223 89.24 89.86 94.59 124.48 116.24 127.16 91.23 122.6266667 3575 3230 3542 2243 3449 4.12E-20 0.607908061 "04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++04137///Mitophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04214///Apoptosis - fly+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04932///Non-alcoholic fatty liver disease+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0032590///dendrite membrane+++GO:0032991///protein-containing complex+++GO:0034399///nuclear periphery+++GO:0043005///neuron projection+++GO:0090575///RNA polymerase II transcription factor complex+++GO:1990037///Lewy body core+++GO:1990589///ATF4-CREB1 transcription factor complex+++GO:1990590///ATF1-ATF4 transcription factor complex+++GO:1990617///CHOP-ATF4 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008140///cAMP response element binding protein binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043522///leucine zipper domain binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006094///gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006874///cellular calcium ion homeostasis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007623///circadian rhythm+++GO:0009636///response to toxic substance+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0030182///neuron differentiation+++GO:0030282///bone mineralization+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031667///response to nutrient levels+++GO:0032922///circadian regulation of gene expression+++GO:0034198///cellular response to amino acid starvation+++GO:0034599///cellular response to oxidative stress+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035162///embryonic hemopoiesis+++GO:0036091///positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0042149///cellular response to glucose starvation+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043267///negative regulation of potassium ion transport+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045667///regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048167///regulation of synaptic plasticity+++GO:0048511///rhythmic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070169///positive regulation of biomineral tissue development+++GO:0070309///lens fiber cell morphogenesis+++GO:0070982///L-asparagine metabolic process+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903351///cellular response to dopamine+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:1990253///cellular response to leucine starvation+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:1990737///response to manganese-induced endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport" 11920 11920 'Atm' mRNA 396 437 396 1.71 1.87 1.81 1.78 1.42 1.52 1.796666667 1.573333333 474 369 392 409.6666667 411.6666667 0.978276716 -0.006127495 01524///Platinum drug resistance+++03440///Homologous recombination+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04218///Cellular senescence+++05131///Shigellosis+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990391///DNA repair complex" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004677///DNA-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding "GO:0000077///DNA damage checkpoint+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001541///ovarian follicle development+++GO:0001666///response to hypoxia+++GO:0001756///somitogenesis+++GO:0002331///pre-B cell allelic exclusion+++GO:0002376///immune system process+++GO:0002377///immunoglobulin production+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007140///male meiotic nuclear division+++GO:0007143///female meiotic nuclear division+++GO:0007292///female gamete generation+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008340///determination of adult lifespan+++GO:0008585///female gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009791///post-embryonic development+++GO:0010212///response to ionizing radiation+++GO:0010506///regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0030889///negative regulation of B cell proliferation+++GO:0032210///regulation of telomere maintenance via telomerase+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0033129///positive regulation of histone phosphorylation+++GO:0033151///V(D)J recombination+++GO:0035264///multicellular organism growth+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0042159///lipoprotein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045141///meiotic telomere clustering+++GO:0045785///positive regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048538///thymus development+++GO:0048599///oocyte development+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0071044///histone mRNA catabolic process+++GO:0071300///cellular response to retinoic acid+++GO:0071480///cellular response to gamma radiation+++GO:0071481///cellular response to X-ray+++GO:0071500///cellular response to nitrosative stress+++GO:0090399///replicative senescence+++GO:0097694///establishment of RNA localization to telomere+++GO:1901216///positive regulation of neuron death+++GO:1903626///positive regulation of DNA catabolic process+++GO:1903978///regulation of microglial cell activation+++GO:1904262///negative regulation of TORC1 signaling+++GO:1904354///negative regulation of telomere capping+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1904884///positive regulation of telomerase catalytic core complex assembly+++GO:1905843///regulation of cellular response to gamma radiation+++GO:2001022///positive regulation of response to DNA damage stimulus" 11921 11921 'Atoh1' mRNA 395 454 435 10.54 11.93 12.31 1.28 1.33 1.8 11.59333333 1.47 55 56 75 428 62 4.81E-50 -2.799554228 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0042667///auditory receptor cell fate specification+++GO:0042668///auditory receptor cell fate determination+++GO:0043066///negative regulation of apoptotic process+++GO:0045609///positive regulation of inner ear auditory receptor cell differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:2000982///positive regulation of inner ear receptor cell differentiation" 11923 11923 'Neurod4' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity" "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007405///neuroblast proliferation+++GO:0010001///glial cell differentiation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0035881///amacrine cell differentiation+++GO:0043010///camera-type eye development+++GO:0045165///cell fate commitment+++GO:0045597///positive regulation of cell differentiation+++GO:0048666///neuron development+++GO:0060041///retina development in camera-type eye" 11924 11924 'Neurog2' mRNA 11 22 9 0.28 0.55 0.24 0.24 0.52 0.34 0.356666667 0.366666667 11 23 15 14 16.33333333 0.805180392 0.228955784 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0021954///central nervous system neuron development+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030900///forebrain development+++GO:0045165///cell fate commitment+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0051091///positive regulation of DNA-binding transcription factor activity" 11925 11925 'Neurog3' mRNA 2 0 0 0.08 0 0 0 0 0 0.026666667 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 04950///Maturity onset diabetes of the young GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021510///spinal cord development+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030855///epithelial cell differentiation+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0031018///endocrine pancreas development+++GO:0045597///positive regulation of cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048814///regulation of dendrite morphogenesis+++GO:0060290///transdifferentiation" 11927 11927 'Atox1' mRNA 1190 1104 1272 192.8 178.78 218.81 319.43 371.59 346.77 196.7966667 345.93 2243 2532 2343 1188.666667 2372.666667 1.83E-25 0.983155585 04978///Mineral absorption GO:0005829///cytosol GO:0005507///copper ion binding+++GO:0016531///copper chaperone activity+++GO:0032767///copper-dependent protein binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding+++GO:1903136///cuprous ion binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0006979///response to oxidative stress+++GO:0043066///negative regulation of apoptotic process+++GO:0060003///copper ion export 11928 11928 'Atp1a1' mRNA 13010 13073 5176 190.5 188.3 80.39 63.4 64.05 72.95 153.0633333 66.8 4983 4918 5553 10419.66667 5151.333333 0.016367244 -1.00801452 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005901///caveola+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0031090///organelle membrane+++GO:0032991///protein-containing complex+++GO:0036126///sperm flagellum+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0016791///phosphatase activity+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030506///ankyrin binding+++GO:0030955///potassium ion binding+++GO:0031402///sodium ion binding+++GO:0043531///ADP binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding+++GO:1990239///steroid hormone binding GO:0002026///regulation of the force of heart contraction+++GO:0002028///regulation of sodium ion transport+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0008217///regulation of blood pressure+++GO:0009410///response to xenobiotic stimulus+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0016311///dephosphorylation+++GO:0030007///cellular potassium ion homeostasis+++GO:0031947///negative regulation of glucocorticoid biosynthetic process+++GO:0036376///sodium ion export across plasma membrane+++GO:0042493///response to drug+++GO:0045822///negative regulation of heart contraction+++GO:0045823///positive regulation of heart contraction+++GO:0045989///positive regulation of striated muscle contraction+++GO:0055085///transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0071260///cellular response to mechanical stimulus+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086009///membrane repolarization+++GO:1902600///proton transmembrane transport+++GO:1903416///response to glycoside+++GO:1990573///potassium ion import across plasma membrane 11931 11931 'Atp1b1' mRNA 15086.57 15411.25 11107.98 323.57 325.39 252.72 112.42 124.67 120.64 300.56 119.2433333 6029.16 6529.79 6264.16 13868.6 6274.37 2.67E-45 -1.148047163 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005901///caveola+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030315///T-tubule+++GO:0031090///organelle membrane+++GO:0036126///sperm flagellum+++GO:0042383///sarcolemma+++GO:0043209///myelin sheath "GO:0001671///ATPase activator activity+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008900///potassium:proton exchanging ATPase activity+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0046982///protein heterodimerization activity+++GO:0051117///ATPase binding" GO:0001666///response to hypoxia+++GO:0001824///blastocyst development+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006883///cellular sodium ion homeostasis+++GO:0007155///cell adhesion+++GO:0010155///regulation of proton transport+++GO:0010243///response to organonitrogen compound+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010468///regulation of gene expression+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0030001///metal ion transport+++GO:0030007///cellular potassium ion homeostasis+++GO:0032496///response to lipopolysaccharide+++GO:0032781///positive regulation of ATPase activity+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0035725///sodium ion transmembrane transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0045851///pH reduction+++GO:0046034///ATP metabolic process+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0055119///relaxation of cardiac muscle+++GO:0060048///cardiac muscle contraction+++GO:0072659///protein localization to plasma membrane+++GO:0086009///membrane repolarization+++GO:0098655///cation transmembrane transport+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1903169///regulation of calcium ion transmembrane transport+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:1903281///positive regulation of calcium:sodium antiporter activity+++GO:1903288///positive regulation of potassium ion import+++GO:1903408///positive regulation of sodium:potassium-exchanging ATPase activity+++GO:1990573///potassium ion import across plasma membrane 11932 11932 'Atp1b2' mRNA 25177 25416 22759 457.91 453.61 440.02 416.26 424.47 410.7 450.5133333 417.1433333 26205 26147 25065 24450.66667 25805.66667 0.207462486 0.067845435 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0031253///cell projection membrane+++GO:0044298///cell body membrane+++GO:0071944///cell periphery+++GO:0097449///astrocyte projection+++GO:0097450///astrocyte end-foot+++GO:0098984///neuron to neuron synapse "GO:0001671///ATPase activator activity+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0030674///protein binding, bridging+++GO:0046982///protein heterodimerization activity+++GO:0051117///ATPase binding" GO:0001895///retina homeostasis+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0007155///cell adhesion+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010976///positive regulation of neuron projection development+++GO:0021670///lateral ventricle development+++GO:0021678///third ventricle development+++GO:0021944///neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration+++GO:0030007///cellular potassium ion homeostasis+++GO:0031589///cell-substrate adhesion+++GO:0032781///positive regulation of ATPase activity+++GO:0036376///sodium ion export across plasma membrane+++GO:0045494///photoreceptor cell maintenance+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0061744///motor behavior+++GO:0086009///membrane repolarization+++GO:0120036///plasma membrane bounded cell projection organization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:1903288///positive regulation of potassium ion import+++GO:1903976///negative regulation of glial cell migration+++GO:1990573///potassium ion import across plasma membrane 11933 11933 'Atp1b3' mRNA 11894 12406 11513 341.81 351.17 351.13 335.63 342.44 330.15 348.0366667 336.0733333 13422 13372 12779 11937.66667 13191 0.013022011 0.132822731 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0036126///sperm flagellum+++GO:0042470///melanosome "GO:0001671///ATPase activator activity+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0030001///metal ion transport+++GO:0030007///cellular potassium ion homeostasis+++GO:0032781///positive regulation of ATPase activity+++GO:0035725///sodium ion transmembrane transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0071805///potassium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0086009///membrane repolarization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:1903288///positive regulation of potassium ion import+++GO:1990573///potassium ion import across plasma membrane 11936 11936 'Fxyd2' mRNA 207 156 193 29.2 21.48 27.39 19.75 15.4 21.31 26.02333333 18.82 170 124 174 185.3333333 156 0.283342485 -0.265161972 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0017080///sodium channel regulator activity+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0008285///negative regulation of cell proliferation+++GO:0043269///regulation of ion transport+++GO:0071475///cellular hyperosmotic salinity response+++GO:0098662///inorganic cation transmembrane transport+++GO:1903406///regulation of sodium:potassium-exchanging ATPase activity+++GO:1903407///negative regulation of sodium:potassium-exchanging ATPase activity+++GO:2000649///regulation of sodium ion transmembrane transporter activity 11937 11937 'Atp2a1' mRNA 19 15 14 0.3 0.23 0.24 0.11 0.2 0.18 0.256666667 0.163333333 8 14 13 16 11.66666667 0.57622889 -0.460734289 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031673///H zone+++GO:0031674///I band+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0005338///nucleotide-sugar transmembrane transporter activity+++GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0016887///ATPase activity+++GO:0030899///calcium-dependent ATPase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006937///regulation of muscle contraction+++GO:0006942///regulation of striated muscle contraction+++GO:0008637///apoptotic mitochondrial changes+++GO:0015931///nucleobase-containing compound transport+++GO:0031448///positive regulation of fast-twitch skeletal muscle fiber contraction+++GO:0032470///positive regulation of endoplasmic reticulum calcium ion concentration+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0034220///ion transmembrane transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043434///response to peptide hormone+++GO:0045988///negative regulation of striated muscle contraction+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0051659///maintenance of mitochondrion location+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0090076///relaxation of skeletal muscle+++GO:0106134///positive regulation of cardiac muscle cell contraction+++GO:1901264///carbohydrate derivative transport+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:1902082///positive regulation of calcium ion import into sarcoplasmic reticulum+++GO:1990036///calcium ion import into sarcoplasmic reticulum 11938 11938 'Atp2a2' mRNA 1670 1625 1544 20.26 19.4 19.87 16.05 14.38 16.15 19.84333333 15.52666667 1536 1343 1496 1613 1458.333333 0.06322772 -0.157478024 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012506///vesicle membrane+++GO:0014704///intercalated disc+++GO:0014801///longitudinal sarcoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0061831///apical ectoplasmic specialization+++GO:0090534///calcium ion-transporting ATPase complex+++GO:0097470///ribbon synapse+++GO:0120025///plasma membrane bounded cell projection "GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0031775///lutropin-choriogonadotropic hormone receptor binding+++GO:0044325///ion channel binding+++GO:0044548///S100 protein binding+++GO:0046872///metal ion binding+++GO:0086039///calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential" GO:0000045///autophagosome assembly+++GO:0002026///regulation of the force of heart contraction+++GO:0003009///skeletal muscle contraction+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006937///regulation of muscle contraction+++GO:0006984///ER-nucleus signaling pathway+++GO:0006996///organelle organization+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0014883///transition between fast and slow fiber+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0016240///autophagosome membrane docking+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032470///positive regulation of endoplasmic reticulum calcium ion concentration+++GO:0032496///response to lipopolysaccharide+++GO:0033292///T-tubule organization+++GO:0034220///ion transmembrane transport+++GO:0034599///cellular response to oxidative stress+++GO:0034605///cellular response to heat+++GO:0043434///response to peptide hormone+++GO:0045822///negative regulation of heart contraction+++GO:0055119///relaxation of cardiac muscle+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0140056///organelle localization by membrane tethering+++GO:1900121///negative regulation of receptor binding+++GO:1903233///regulation of calcium ion-dependent exocytosis of neurotransmitter+++GO:1903515///calcium ion transport from cytosol to endoplasmic reticulum+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering 11941 11941 'Atp2b2' mRNA 4272 4270 4113 28.84 28.9 30.2 2.03 2.02 1.76 29.31333333 1.936666667 344 315 288 4218.333333 315.6666667 0 -3.752622375 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04925///Aldosterone synthesis and secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04972///Pancreatic secretion+++04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032591///dendritic spine membrane+++GO:0032809///neuronal cell body membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0030165///PDZ domain binding+++GO:0030899///calcium-dependent ATPase activity+++GO:0035254///glutamate receptor binding+++GO:0046872///metal ion binding+++GO:1905056///calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration+++GO:1905059///calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration GO:0000902///cell morphogenesis+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006996///organelle organization+++GO:0007595///lactation+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0008361///regulation of cell size+++GO:0021549///cerebellum development+++GO:0021692///cerebellar Purkinje cell layer morphogenesis+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021707///cerebellar granule cell differentiation+++GO:0030182///neuron differentiation+++GO:0040011///locomotion+++GO:0042428///serotonin metabolic process+++GO:0042472///inner ear morphogenesis+++GO:0045299///otolith mineralization+++GO:0046068///cGMP metabolic process+++GO:0048167///regulation of synaptic plasticity+++GO:0048839///inner ear development+++GO:0050808///synapse organization+++GO:0050885///neuromuscular process controlling balance+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051928///positive regulation of calcium ion transport+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060113///inner ear receptor cell differentiation+++GO:0070588///calcium ion transmembrane transport+++GO:0090102///cochlea development+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration 11944 11944 'Atp4a' mRNA 11 6 12 0.17 0.09 0.2 0.16 0.14 0.08 0.153333333 0.126666667 12 10 6 9.666666667 9.333333333 0.945809537 -0.07419454 00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++04971///Gastric acid secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0008900///potassium:proton exchanging ATPase activity+++GO:0030955///potassium ion binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0009410///response to xenobiotic stimulus+++GO:0010155///regulation of proton transport+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0030007///cellular potassium ion homeostasis+++GO:0036376///sodium ion export across plasma membrane+++GO:0042493///response to drug+++GO:0045851///pH reduction+++GO:0071805///potassium ion transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 11946 11946 'Atp5a1' mRNA 15287 15961 15064 351.05 360.88 366.96 351.76 329.63 352.31 359.63 344.5666667 17618 16121 17083 15437.33333 16940.66667 0.023663902 0.121713853 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0005754///mitochondrial proton-transporting ATP synthase, catalytic core+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0045259///proton-transporting ATP synthase complex+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0032559///adenyl ribonucleotide binding+++GO:0042288///MHC class I protein binding+++GO:0043531///ADP binding+++GO:0043532///angiostatin binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006629///lipid metabolic process+++GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0009790///embryo development+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0046034///ATP metabolic process+++GO:1902600///proton transmembrane transport 11947 11947 'Atp5b' mRNA 27333 27972 27716 834.08 841.11 897.24 839.61 854.36 845.82 857.4766667 846.5966667 31627 31415 30835 27673.66667 31292.33333 0.002648123 0.164540622 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0045259///proton-transporting ATP synthase complex+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030228///lipoprotein particle receptor activity+++GO:0042288///MHC class I protein binding+++GO:0043531///ADP binding+++GO:0043532///angiostatin binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0001525///angiogenesis+++GO:0006629///lipid metabolic process+++GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0006898///receptor-mediated endocytosis+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0046034///ATP metabolic process+++GO:0051453///regulation of intracellular pH+++GO:0098761///cellular response to interleukin-7+++GO:1902600///proton transmembrane transport 11949 11949 'Atp5c1' mRNA 5918 6116 5703 315.62 325.31 324.2 325.93 341.49 324.32 321.71 330.58 7008 7135 6737 5912.333333 6960 7.83E-05 0.224335062 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process 11950 11950 'Atp5pb' mRNA 4396 4702 4440 240.59 254.15 257.79 321.58 314.24 305.37 250.8433333 313.73 6742 6424 6190 4512.666667 6452 5.63E-18 0.503473263 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0015078///proton transmembrane transporter activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport 11951 11951 'Atp5g1' mRNA 3599 3297 3320 307.29 278.79 300.29 374.53 440 390.82 295.4566667 401.7833333 5031 5755 5069 3405.333333 5285 2.09E-16 0.623411817 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0033177///proton-transporting two-sector ATPase complex, proton-transporting domain+++GO:0034703///cation channel complex+++GO:0043025///neuronal cell body+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0150034///distal axon" GO:0008289///lipid binding+++GO:0015078///proton transmembrane transporter activity+++GO:0022834///ligand-gated channel activity "GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0009631///cold acclimation+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0015986///ATP synthesis coupled proton transport+++GO:0045471///response to ethanol+++GO:0045773///positive regulation of axon extension+++GO:0046034///ATP metabolic process+++GO:0046931///pore complex assembly+++GO:1901216///positive regulation of neuron death+++GO:1902600///proton transmembrane transport+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1905232///cellular response to L-glutamate+++GO:1905242///response to 3,3',5-triiodo-L-thyronine" 11957 11957 'Atp5j' mRNA 7190.96 7256 7485.88 895.14 874.46 999.62 799.64 916.33 802.78 923.0733333 839.5833333 7206.84 7990.83 7099.87 7310.946667 7432.513333 0.907954312 0.011098508 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006811///ion transport+++GO:0010460///positive regulation of heart rate+++GO:0014850///response to muscle activity+++GO:0015986///ATP synthesis coupled proton transport+++GO:0032307///negative regulation of prostaglandin secretion+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0045777///positive regulation of blood pressure+++GO:0046034///ATP metabolic process+++GO:1900139///negative regulation of arachidonic acid secretion 11958 11958 'Atp5k' mRNA 383 441 633 155.09 182.19 273.68 156.05 185.55 197.06 203.6533333 179.5533333 430 494 520 485.6666667 481.3333333 0.884172289 -0.034782228 00190///Oxidative phosphorylation+++04714///Thermogenesis "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0015078///proton transmembrane transporter activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process 11964 11964 'Atp6v1a' mRNA 5244 5486 5045 67.6 69.46 68.85 70.65 69.12 68.89 68.63666667 69.55333333 6305 6040 5958 5258.333333 6101 2.07E-04 0.203105237 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016324///apical plasma membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle" "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0015986///ATP synthesis coupled proton transport+++GO:0036295///cellular response to increased oxygen levels+++GO:0046034///ATP metabolic process+++GO:1902600///proton transmembrane transport 11966 11966 'Atp6v1b2' mRNA 2945 3155 3026 59.39 62.63 64.73 78.39 78.71 77.54 62.25 78.21333333 4472 4385 4283 3042 4380 1.62E-16 0.513614456 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0042470///melanosome+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle" GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006811///ion transport+++GO:0046034///ATP metabolic process+++GO:1902600///proton transmembrane transport 11972 11972 'Atp6v0d1' mRNA 3308 3517 2391 116.86 122.49 89.61 120.27 115.14 112.64 109.6533333 116.0166667 3912 3655 3545 3072 3704 0.006540134 0.265326695 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++05323///Rheumatoid arthritis "GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005813///centrosome+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0032991///protein-containing complex+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0033181///plasma membrane proton-transporting V-type ATPase complex+++GO:0043005///neuron projection+++GO:0043679///axon terminus" "GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0044877///protein-containing complex binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007034///vacuolar transport+++GO:0007035///vacuolar acidification+++GO:0007420///brain development+++GO:0030030///cell projection organization+++GO:0036295///cellular response to increased oxygen levels+++GO:0060271///cilium assembly+++GO:1902600///proton transmembrane transport 11973 11973 'Atp6v1e1' mRNA 3153 3200 3082 158.68 159.04 164.57 190.66 196.75 195.59 160.7633333 194.3333333 4348 4376 4313 3145 4345.666667 1.95E-14 0.454884754 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0033178///proton-transporting two-sector ATPase complex, catalytic domain" "GO:0005515///protein binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0016787///hydrolase activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 11974 11974 'Atp6v0e' mRNA 4535 4820 4538 388.09 408.88 412.12 482.64 485.06 458.78 403.03 475.4933333 6455 6317 5924 4631 6232 2.26E-12 0.416428129 00190///Oxidative phosphorylation+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033179///proton-transporting V-type ATPase, V0 domain" "GO:0015078///proton transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 11975 11975 'Atp6v0a1' mRNA 5305 5255 4656 73.13 70.75 68.14 42.93 43.61 43.12 70.67333333 43.22 3536 3534 3411 5072 3493.666667 1.23E-21 -0.547401088 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0016607///nuclear speck+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0042470///melanosome+++GO:0043229///intracellular organelle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm" "GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:0007035///vacuolar acidification+++GO:0016241///regulation of macroautophagy+++GO:1901998///toxin transport+++GO:1902600///proton transmembrane transport 11977 11977 'Atp7a' mRNA 843 859 703 5.41 5.42 4.78 8.4 7.29 8.44 5.203333333 8.043333333 1508 1278 1468 801.6666667 1418 1.06E-18 0.813246871 01524///Platinum drug resistance+++04978///Mineral absorption GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031901///early endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0033162///melanosome membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0005375///copper ion transmembrane transporter activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016532///superoxide dismutase copper chaperone activity+++GO:0019829///cation-transporting ATPase activity+++GO:0031267///small GTPase binding+++GO:0032767///copper-dependent protein binding+++GO:0043682///copper-transporting ATPase activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:1903136///cuprous ion binding GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001889///liver development+++GO:0001974///blood vessel remodeling+++GO:0002082///regulation of oxidative phosphorylation+++GO:0006568///tryptophan metabolic process+++GO:0006570///tyrosine metabolic process+++GO:0006584///catecholamine metabolic process+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006825///copper ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0007626///locomotory behavior+++GO:0010041///response to iron(III) ion+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0010273///detoxification of copper ion+++GO:0010468///regulation of gene expression+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0015677///copper ion import+++GO:0018205///peptidyl-lysine modification+++GO:0019430///removal of superoxide radicals+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021860///pyramidal neuron development+++GO:0021954///central nervous system neuron development+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0031069///hair follicle morphogenesis+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0035137///hindlimb morphogenesis+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042093///T-helper cell differentiation+++GO:0042414///epinephrine metabolic process+++GO:0042415///norepinephrine metabolic process+++GO:0042417///dopamine metabolic process+++GO:0042421///norepinephrine biosynthetic process+++GO:0042428///serotonin metabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043473///pigmentation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0045793///positive regulation of cell size+++GO:0045914///negative regulation of catecholamine metabolic process+++GO:0046034///ATP metabolic process+++GO:0046688///response to copper ion+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0048251///elastic fiber assembly+++GO:0048286///lung alveolus development+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0051542///elastin biosynthetic process+++GO:0055070///copper ion homeostasis+++GO:0060003///copper ion export+++GO:0071230///cellular response to amino acid stimulus+++GO:0071236///cellular response to antibiotic+++GO:0071276///cellular response to cadmium ion+++GO:0071279///cellular response to cobalt ion+++GO:0071280///cellular response to copper ion+++GO:0071281///cellular response to iron ion+++GO:0071284///cellular response to lead ion+++GO:0071456///cellular response to hypoxia+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1903036///positive regulation of response to wounding+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1904959///regulation of cytochrome-c oxidase activity+++GO:1904960///positive regulation of cytochrome-c oxidase activity 11979 11979 'Atp7b' mRNA 30 30 46 0.23 0.23 0.38 0.09 0.12 0.1 0.28 0.103333333 13 17 14 35.33333333 14.66666667 0.01595005 -1.289206243 01524///Platinum drug resistance+++04978///Mineral absorption GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031901///early endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0033162///melanosome membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070160///tight junction GO:0000166///nucleotide binding+++GO:0005375///copper ion transmembrane transporter activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016532///superoxide dismutase copper chaperone activity+++GO:0019829///cation-transporting ATPase activity+++GO:0031267///small GTPase binding+++GO:0032767///copper-dependent protein binding+++GO:0043682///copper-transporting ATPase activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:1903136///cuprous ion binding GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001889///liver development+++GO:0001974///blood vessel remodeling+++GO:0002082///regulation of oxidative phosphorylation+++GO:0006568///tryptophan metabolic process+++GO:0006570///tyrosine metabolic process+++GO:0006584///catecholamine metabolic process+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006825///copper ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0007626///locomotory behavior+++GO:0010041///response to iron(III) ion+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0010273///detoxification of copper ion+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0015677///copper ion import+++GO:0015680///protein maturation by copper ion transfer+++GO:0018205///peptidyl-lysine modification+++GO:0019430///removal of superoxide radicals+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021860///pyramidal neuron development+++GO:0021954///central nervous system neuron development+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0031069///hair follicle morphogenesis+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0034220///ion transmembrane transport+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0035434///copper ion transmembrane transport+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042093///T-helper cell differentiation+++GO:0042414///epinephrine metabolic process+++GO:0042415///norepinephrine metabolic process+++GO:0042417///dopamine metabolic process+++GO:0042421///norepinephrine biosynthetic process+++GO:0042428///serotonin metabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043473///pigmentation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0045793///positive regulation of cell size+++GO:0045914///negative regulation of catecholamine metabolic process+++GO:0046034///ATP metabolic process+++GO:0046688///response to copper ion+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0048251///elastic fiber assembly+++GO:0048286///lung alveolus development+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051208///sequestering of calcium ion+++GO:0051216///cartilage development+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0051542///elastin biosynthetic process+++GO:0055070///copper ion homeostasis+++GO:0060003///copper ion export+++GO:0071230///cellular response to amino acid stimulus+++GO:0071236///cellular response to antibiotic+++GO:0071276///cellular response to cadmium ion+++GO:0071279///cellular response to cobalt ion+++GO:0071280///cellular response to copper ion+++GO:0071281///cellular response to iron ion+++GO:0071284///cellular response to lead ion+++GO:0071456///cellular response to hypoxia+++GO:0098655///cation transmembrane transport+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1903036///positive regulation of response to wounding+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1904959///regulation of cytochrome-c oxidase activity+++GO:1904960///positive regulation of cytochrome-c oxidase activity 11980 11980 'Atp8a1' mRNA 2160 2130 1688 14.03 13.61 11.63 6.76 6.36 7.11 13.09 6.743333333 1200 1082 1192 1992.666667 1158 3.11E-20 -0.790787789 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031090///organelle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042584///chromaffin granule membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990531///phospholipid-translocating ATPase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0007612///learning+++GO:0015914///phospholipid transport+++GO:0030335///positive regulation of cell migration+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation+++GO:0055085///transmembrane transport+++GO:0061092///positive regulation of phospholipid translocation 11981 11981 'Atp9a' mRNA 3172 3221 3046 52.32 51.22 51.7 41.57 40.9 42.42 51.74666667 41.63 3001.97 2906 2892 3146.333333 2933.323333 0.088414481 -0.112884962 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0002020///protease binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006897///endocytosis+++GO:0015914///phospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation+++GO:1903542///negative regulation of exosomal secretion+++GO:1905279///regulation of retrograde transport, endosome to Golgi+++GO:2001135///regulation of endocytic recycling" 11982 11982 'Atp10a' mRNA 301 308 180 3 3.02 1.98 1.96 2.29 2.29 2.666666667 2.18 217 253 248 263 239.3333333 0.584620285 -0.13601265 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990531///phospholipid-translocating ATPase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0045332///phospholipid translocation+++GO:1903527///positive regulation of membrane tubulation 11983 11983 'Atpif1' mRNA 2292 2219 2406 134.53 128.94 150.1 151.99 165.96 157.88 137.8566667 158.61 2971 3163 2988 2305.666667 3040.666667 1.51E-06 0.385551606 GO:0005739///mitochondrion+++GO:0009986///cell surface+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0019899///enzyme binding+++GO:0042030///ATPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0043532///angiostatin binding+++GO:0051117///ATPase binding+++GO:0140260///mitochondrial proton-transporting ATP synthase complex binding GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006783///heme biosynthetic process+++GO:0030218///erythrocyte differentiation+++GO:0032780///negative regulation of ATPase activity+++GO:0043086///negative regulation of catalytic activity+++GO:0051346///negative regulation of hydrolase activity+++GO:0051882///mitochondrial depolarization+++GO:0072593///reactive oxygen species metabolic process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:1903578///regulation of ATP metabolic process+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 11984 11984 'Atp6v0c' mRNA 14280 14368 13596 797.98 794.77 801.6 1437.45 1395.95 1415.85 798.1166667 1416.416667 29315 27825 28046 14081.33333 28395.33333 2.06E-112 1.000082784 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0005764///lysosome+++GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033177///proton-transporting two-sector ATPase complex, proton-transporting domain+++GO:0033179///proton-transporting V-type ATPase, V0 domain" "GO:0005515///protein binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015078///proton transmembrane transporter activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0007035///vacuolar acidification+++GO:0007042///lysosomal lumen acidification+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1902600///proton transmembrane transport+++GO:1904093///negative regulation of autophagic cell death 11987 11987 'Slc7a1' mRNA 1021 1107 770 7.54 8.04 6.04 5.14 5.08 5.16 7.206666667 5.126666667 800 777 781 966 786 0.009259389 -0.302697018 05206///MicroRNAs in cancer GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0032991///protein-containing complex GO:0000064///L-ornithine transmembrane transporter activity+++GO:0005290///L-histidine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006865///amino acid transport+++GO:0015807///L-amino acid transport+++GO:0015809///arginine transport+++GO:0015819///lysine transport+++GO:0015822///ornithine transport+++GO:0032006///regulation of TOR signaling+++GO:0042102///positive regulation of T cell proliferation+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:0097638///L-arginine import across plasma membrane+++GO:1903352///L-ornithine transmembrane transport+++GO:1903401///L-lysine transmembrane transport+++GO:1903810///L-histidine import across plasma membrane+++GO:1903826///arginine transmembrane transport+++GO:1990822///basic amino acid transmembrane transport 11988 11988 'Slc7a2' mRNA 1234.3 1249 1095 8.21 8.24 7.82 8.13 7.07 7.32 8.09 7.506666667 1394 1183 1216.04 1192.766667 1264.346667 0.491533248 0.073090011 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0000064///L-ornithine transmembrane transporter activity+++GO:0005289///high-affinity arginine transmembrane transporter activity+++GO:0005292///high-affinity lysine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity+++GO:0097626///low-affinity L-arginine transmembrane transporter activity+++GO:0097627///high-affinity L-ornithine transmembrane transporter activity GO:0002537///nitric oxide production involved in inflammatory response+++GO:0006809///nitric oxide biosynthetic process+++GO:0006865///amino acid transport+++GO:0015807///L-amino acid transport+++GO:0015809///arginine transport+++GO:0042116///macrophage activation+++GO:0043030///regulation of macrophage activation+++GO:0050727///regulation of inflammatory response+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:0097638///L-arginine import across plasma membrane+++GO:0097639///L-lysine import across plasma membrane+++GO:0097640///L-ornithine import across plasma membrane+++GO:1902023///L-arginine transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1903352///L-ornithine transmembrane transport+++GO:1903401///L-lysine transmembrane transport+++GO:1903826///arginine transmembrane transport 11989 11989 'Slc7a3' mRNA 19 28 20 0.44 0.66 0.47 0.15 0.29 0.4 0.523333333 0.28 9 13 18 22.33333333 13.33333333 0.266909544 -0.748935543 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000064///L-ornithine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006865///amino acid transport+++GO:0015809///arginine transport+++GO:0015819///lysine transport+++GO:0015822///ornithine transport+++GO:0032006///regulation of TOR signaling+++GO:0055085///transmembrane transport+++GO:0097638///L-arginine import across plasma membrane+++GO:0097639///L-lysine import across plasma membrane+++GO:0097640///L-ornithine import across plasma membrane+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1903352///L-ornithine transmembrane transport+++GO:1903826///arginine transmembrane transport 11990 11990 'Atrn' mRNA 1919.44 1876.01 1567.95 8.71 8.45 7.45 5.25 4.31 4.73 8.203333333 4.763333333 1320.01 1090 1154.12 1787.8 1188.043333 6.30E-12 -0.599118508 GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity GO:0006954///inflammatory response+++GO:0006979///response to oxidative stress+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0021549///cerebellum development+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0040014///regulation of multicellular organism growth+++GO:0042552///myelination+++GO:0043473///pigmentation 11991 11991 'Hnrnpd' mRNA 580.08 589 522 4.32 4.34 4.09 3.58 3.31 3.31 4.25 3.4 569 498 509.01 563.6933333 525.3366667 0.399350165 -0.112637626 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042162///telomeric DNA binding+++GO:0042826///histone deacetylase binding GO:0001889///liver development+++GO:0007420///brain development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0021549///cerebellum development+++GO:0032204///regulation of telomere maintenance+++GO:0032355///response to estradiol+++GO:0042752///regulation of circadian rhythm+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048255///mRNA stabilization+++GO:0048511///rhythmic process+++GO:0051592///response to calcium ion+++GO:0051602///response to electrical stimulus+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0071230///cellular response to amino acid stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0097167///circadian regulation of translation+++GO:1901355///response to rapamycin+++GO:1904355///positive regulation of telomere capping+++GO:1904383///response to sodium phosphate+++GO:1904586///cellular response to putrescine+++GO:1905663///positive regulation of telomerase RNA reverse transcriptase activity+++GO:1990828///hepatocyte dedifferentiation 11992 11992 'Auh' mRNA 1032 1099 1107 44.2 46.29 49.91 31.18 35.81 30.75 46.8 32.58 847 939 804 1079.333333 863.3333333 0.001543388 -0.334613288 "00280///Valine, leucine and isoleucine degradation" GO:0005739///mitochondrion GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003824///catalytic activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0004490///methylglutaconyl-CoA hydratase activity+++GO:0016829///lyase activity+++GO:0050011///itaconyl-CoA hydratase activity GO:0006552///leucine catabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009083///branched-chain amino acid catabolic process 11993 11993 'Aup1' mRNA 2782 2782 2695 98.85 97.51 101.93 126.23 127.19 119.48 99.43 124.3 4082 4014 3735 2753 3943.666667 1.47E-15 0.506516867 GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0097027///ubiquitin-protein transferase activator activity "GO:0009615///response to virus+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034389///lipid droplet organization+++GO:0050790///regulation of catalytic activity+++GO:0061724///lipophagy+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0140042///lipid droplet formation+++GO:1990044///protein localization to lipid droplet" 11994 11994 'Pcdh15' mRNA 880 910 763 5.72 5.69 5.23 0.67 0.69 0.66 5.546666667 0.673333333 117 96 127 851 113.3333333 6.02E-101 -2.918091627 GO:0001750///photoreceptor outer segment+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0045202///synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0001964///startle response+++GO:0002009///morphogenesis of an epithelium+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008344///adult locomotory behavior+++GO:0035264///multicellular organism growth+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0048839///inner ear development+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0050973///detection of mechanical stimulus involved in equilibrioception+++GO:0051017///actin filament bundle assembly+++GO:0051592///response to calcium ion+++GO:0060013///righting reflex+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:1905515///non-motile cilium assembly 11997 11997 'Akr1b7' mRNA 3 2 4 0.15 0.1 0.21 0.13 0.09 0 0.153333333 0.073333333 3 2 0 3 1.666666667 0.68267686 -0.878688335 00040///Pentose and glucuronate interconversions+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00561///Glycerolipid metabolism+++00790///Folate biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0036130///prostaglandin H2 endoperoxidase reductase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0047718///indanol dehydrogenase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0052650///NADP-retinol dehydrogenase activity GO:0001523///retinoid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0016488///farnesol catabolic process+++GO:0042572///retinol metabolic process+++GO:0044255///cellular lipid metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0110095///cellular detoxification of aldehyde 12000 12000 'Avpr2' mRNA 6 4 5 0.31 0.13 0.17 0.14 0.23 0.12 0.203333333 0.163333333 4 7 4 5 5 0.998591786 -0.009319332 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04962///Vasopressin-regulated water reabsorption GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0004930///G protein-coupled receptor activity+++GO:0005000///vasopressin receptor activity+++GO:0042277///peptide binding GO:0001992///regulation of systemic arterial blood pressure by vasopressin+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0021537///telencephalon development+++GO:0032609///interferon-gamma production+++GO:0034097///response to cytokine+++GO:0035811///negative regulation of urine volume+++GO:0035814///negative regulation of renal sodium excretion+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction 12005 12005 'Axin1' mRNA 374 317 368 6.69 5.48 7.09 5.85 6.01 5.81 6.42 5.89 379 376 370 353 375 0.704337067 0.073011304 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030877///beta-catenin destruction complex+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:1990909///Wnt signalosome GO:0002039///p53 binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0046332///SMAD binding+++GO:0060090///molecular adaptor activity+++GO:0070016///armadillo repeat domain binding+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding "GO:0000209///protein polyubiquitination+++GO:0001701///in utero embryonic development+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006913///nucleocytoplasmic transport+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0007628///adult walking behavior+++GO:0009950///dorsal/ventral axis specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0016055///Wnt signaling pathway+++GO:0020027///hemoglobin metabolic process+++GO:0030163///protein catabolic process+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031122///cytoplasmic microtubule organization+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032147///activation of protein kinase activity+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034101///erythrocyte homeostasis+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0034622///cellular protein-containing complex assembly+++GO:0036342///post-anal tail morphogenesis+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade+++GO:0048318///axial mesoderm development+++GO:0048320///axial mesoderm formation+++GO:0050877///nervous system process+++GO:0051248///negative regulation of protein metabolic process+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0060070///canonical Wnt signaling pathway+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060322///head development+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0071514///genetic imprinting+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process" 12006 12006 'Axin2' mRNA 362 346 241 4.51 4.27 3.2 2.18 1.98 1.89 3.993333333 2.016666667 199 178 168 316.3333333 181.6666667 7.34E-06 -0.805636091 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0070411///I-SMAD binding GO:0001756///somitogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001957///intramembranous ossification+++GO:0003139///secondary heart field specification+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0008219///cell death+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010942///positive regulation of cell death+++GO:0016055///Wnt signaling pathway+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030282///bone mineralization+++GO:0032423///regulation of mismatch repair+++GO:0034613///cellular protein localization+++GO:0042476///odontogenesis+++GO:0043570///maintenance of DNA repeat elements+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0048255///mRNA stabilization+++GO:0061181///regulation of chondrocyte development+++GO:0070602///regulation of centromeric sister chromatid cohesion+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000054///negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification 12007 12007 'Azgp1' mRNA 1 1 0 0.05 0.05 0 0.12 0.08 0.21 0.033333333 0.136666667 3 2 5 0.666666667 3.333333333 0.27838349 2.328757062 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane "GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0040014///regulation of multicellular organism growth" 12009 12009 'Cep131' mRNA 477 514 275 7.18 7.62 4.39 2.19 3.09 2.7 6.396666667 2.66 167 231 200 422 199.3333333 1.38E-07 -1.078568208 GO:0001669///acrosomal vesicle+++GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0034451///centriolar satellite+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007288///sperm axoneme assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0010824///regulation of centrosome duplication+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly+++GO:0071539///protein localization to centrosome+++GO:0090316///positive regulation of intracellular protein transport+++GO:1905198///manchette assembly+++GO:1905515///non-motile cilium assembly+++GO:1990953///intramanchette transport 12010 12010 'B2m' mRNA 17922 17570 17477 1392.11 1351.69 1440.58 4136.25 4363 4193.69 1394.793333 4230.98 60985 62661 59717 17656.33333 61121 1.27E-259 1.779385051 04612///Antigen processing and presentation+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0042612///MHC class I protein complex+++GO:0042613///MHC class II protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:1990712///HFE-transferrin receptor complex GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002237///response to molecule of bacterial origin+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002481///antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002726///positive regulation of T cell cytokine production+++GO:0003254///regulation of membrane depolarization+++GO:0006826///iron ion transport+++GO:0006955///immune response+++GO:0006968///cellular defense response+++GO:0007275///multicellular organism development+++GO:0007611///learning or memory+++GO:0010977///negative regulation of neuron projection development+++GO:0019731///antibacterial humoral response+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0032092///positive regulation of protein binding+++GO:0033077///T cell differentiation in thymus+++GO:0034756///regulation of iron ion transport+++GO:0042026///protein refolding+++GO:0042493///response to drug+++GO:0045087///innate immune response+++GO:0045646///regulation of erythrocyte differentiation+++GO:0046686///response to cadmium ion+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050768///negative regulation of neurogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050870///positive regulation of T cell activation+++GO:0051289///protein homotetramerization+++GO:0055072///iron ion homeostasis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071281///cellular response to iron ion+++GO:0071283///cellular response to iron(III) ion+++GO:0071316///cellular response to nicotine+++GO:0090647///modulation of age-related behavioral decline+++GO:1900121///negative regulation of receptor binding+++GO:1900122///positive regulation of receptor binding+++GO:1904434///positive regulation of ferrous iron binding+++GO:1904437///positive regulation of transferrin receptor binding+++GO:1990000///amyloid fibril formation+++GO:2000774///positive regulation of cellular senescence+++GO:2000978///negative regulation of forebrain neuron differentiation" 12012 12012 'Baat' mRNA 0 0 1 0 0 0.03 0.03 0 0.05 0.01 0.026666667 1 0 2 0.333333333 1 0.73177634 1.463944511 00120///Primary bile acid biosynthesis+++00430///Taurine and hypotaurine metabolism+++01040///Biosynthesis of unsaturated fatty acids+++04146///Peroxisome+++04976///Bile secretion GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol "GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0047963///glycine N-choloyltransferase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0052817///very long chain acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity" GO:0001889///liver development+++GO:0002152///bile acid conjugation+++GO:0006544///glycine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0008206///bile acid metabolic process+++GO:0019530///taurine metabolic process+++GO:0031100///animal organ regeneration 12013 12013 'Bach1' mRNA 401 382 311 3.61 3.38 2.99 7.68 5.03 7.72 3.326666667 6.81 975 625 952 364.6666667 850.6666667 9.43E-16 1.211079294 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000117///regulation of transcription involved in G2/M transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia" 12014 12014 'Bach2' mRNA 715.11 727.15 538.06 1.72 1.71 1.34 0.88 0.96 1.03 1.59 0.956666667 386 450.39 406.85 660.1066667 414.4133333 2.35E-07 -0.677512831 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051170///import into nucleus+++GO:0090721///primary adaptive immune response involving T cells and B cells" 12015 12015 'Bad' mRNA 736.82 793.77 709.72 41.96 46.16 45.94 51.01 59.33 54.54 44.68666667 54.96 925.45 1055.4 979.19 746.77 986.68 1.18E-04 0.393569132 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030346///protein phosphatase 2B binding+++GO:0043422///protein kinase B binding+++GO:0071889///14-3-3 protein binding GO:0001666///response to hypoxia+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006007///glucose catabolic process+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007283///spermatogenesis+++GO:0008283///cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009725///response to hormone+++GO:0009749///response to glucose+++GO:0010033///response to organic substance+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0014070///response to organic cyclic compound+++GO:0019050///suppression by virus of host apoptotic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0021987///cerebral cortex development+++GO:0032024///positive regulation of insulin secretion+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0033133///positive regulation of glucokinase activity+++GO:0033574///response to testosterone+++GO:0034201///response to oleic acid+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042593///glucose homeostasis+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043200///response to amino acid+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044342///type B pancreatic cell proliferation+++GO:0045471///response to ethanol+++GO:0045579///positive regulation of B cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0045862///positive regulation of proteolysis+++GO:0046031///ADP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0046931///pore complex assembly+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051384///response to glucocorticoid+++GO:0051592///response to calcium ion+++GO:0060139///positive regulation of apoptotic process by virus+++GO:0071247///cellular response to chromate+++GO:0071260///cellular response to mechanical stimulus+++GO:0071310///cellular response to organic substance+++GO:0071316///cellular response to nicotine+++GO:0071396///cellular response to lipid+++GO:0071456///cellular response to hypoxia+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:1901216///positive regulation of neuron death+++GO:1901423///response to benzene+++GO:1902220///positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:1904710///positive regulation of granulosa cell apoptotic process+++GO:2000078///positive regulation of type B pancreatic cell development 12017 12017 'Bag1' mRNA 803 841 229 35.78 36.98 10.83 16.57 21.16 22.83 27.86333333 20.18666667 427 532 569 624.3333333 509.3333333 0.714616052 -0.277638964 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding+++GO:0051219///phosphoprotein binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006915///apoptotic process+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0014040///positive regulation of Schwann cell differentiation+++GO:0030182///neuron differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0070585///protein localization to mitochondrion+++GO:0110091///negative regulation of hippocampal neuron apoptotic process+++GO:1905232///cellular response to L-glutamate+++GO:2000672///negative regulation of motor neuron apoptotic process 12018 12018 'Bak1' mRNA 27 28 30 0.77 0.78 0.9 2.27 2.2 2.02 0.816666667 2.163333333 92 87 79 28.33333333 86 2.00E-06 1.587986906 01524///Platinum drug resistance+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04215///Apoptosis - multiple species+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005622///intracellular+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031966///mitochondrial membrane+++GO:0046930///pore complex+++GO:0097136///Bcl-2 family protein complex+++GO:0097145///BAK complex GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding+++GO:0051400///BH domain binding GO:0001776///leukocyte homeostasis+++GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001974///blood vessel remodeling+++GO:0002262///myeloid cell homeostasis+++GO:0002352///B cell negative selection+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007420///brain development+++GO:0007568///aging+++GO:0008053///mitochondrial fusion+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0009620///response to fungus+++GO:0010046///response to mycotoxin+++GO:0010225///response to UV-C+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010332///response to gamma radiation+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010629///negative regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process+++GO:0031018///endocrine pancreas development+++GO:0031100///animal organ regeneration+++GO:0031334///positive regulation of protein complex assembly+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0034644///cellular response to UV+++GO:0035108///limb morphogenesis+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0044346///fibroblast apoptotic process+++GO:0045471///response to ethanol+++GO:0045862///positive regulation of proteolysis+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0051726///regulation of cell cycle+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060068///vagina development+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070242///thymocyte apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1902262///apoptotic process involved in blood vessel morphogenesis 12020 12020 'Nkx3-2' mRNA 2 3 0 0.08 0.12 0 0 0 0.04 0.066666667 0.013333333 0 0 1 1.666666667 0.333333333 0.511411657 -2.193383463 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007368///determination of left/right symmetry+++GO:0030154///cell differentiation+++GO:0031016///pancreas development+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0042474///middle ear morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0048513///animal organ development+++GO:0048536///spleen development+++GO:0048645///animal organ formation+++GO:0048705///skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0055123///digestive system development+++GO:0060576///intestinal epithelial cell development" 12021 12021 'Bard1' mRNA 12 10 8 0.12 0.11 0.08 0.53 0.26 0.53 0.103333333 0.44 51 28 47 10 42 1.21E-04 2.058426166 03440///Homologous recombination GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0031436///BRCA1-BARD1 complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070531///BRCA1-A complex GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0042325///regulation of phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0046826///negative regulation of protein export from nucleus+++GO:0085020///protein K6-linked ubiquitination 12023 12023 'Barx2' mRNA 5 5 5 0.16 0.16 0.17 0 0 0.06 0.163333333 0.02 0 0 2 5 0.666666667 0.122919054 -2.916203291 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001502///cartilage condensation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0014902///myotube differentiation+++GO:0042637///catagen+++GO:0045944///positive regulation of transcription by RNA polymerase II" 12028 12028 'Bax' mRNA 1163 1096 1015 88.76 82.87 82.2 180.07 193.16 166.4 84.61 179.8766667 2702 2824 2412 1091.333333 2646 1.10E-54 1.267706001 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04071///Sphingolipid signaling pathway+++04115///p53 signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04211///Longevity regulating pathway+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04722///Neurotrophin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05417///Lipid and atherosclerosis GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0046930///pore complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0097136///Bcl-2 family protein complex+++GO:0097144///BAX complex+++GO:0097145///BAK complex GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015267///channel activity+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding+++GO:0051400///BH domain binding+++GO:0051434///BH3 domain binding GO:0001541///ovarian follicle development+++GO:0001764///neuron migration+++GO:0001776///leukocyte homeostasis+++GO:0001777///T cell homeostatic proliferation+++GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001822///kidney development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0001974///blood vessel remodeling+++GO:0002262///myeloid cell homeostasis+++GO:0002352///B cell negative selection+++GO:0002358///B cell homeostatic proliferation+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0006808///regulation of nitrogen utilization+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0007008///outer mitochondrial membrane organization+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0007548///sex differentiation+++GO:0008053///mitochondrial fusion+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0008637///apoptotic mitochondrial changes+++GO:0009566///fertilization+++GO:0009611///response to wounding+++GO:0009636///response to toxic substance+++GO:0009651///response to salt stress+++GO:0009791///post-embryonic development+++GO:0010212///response to ionizing radiation+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010332///response to gamma radiation+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0016032///viral process+++GO:0021854///hypothalamus development+++GO:0021987///cerebral cortex development+++GO:0031334///positive regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0032976///release of matrix enzymes from mitochondria+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0034644///cellular response to UV+++GO:0035108///limb morphogenesis+++GO:0035234///ectopic germ cell programmed cell death+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045136///development of secondary sexual characteristics+++GO:0045333///cellular respiration+++GO:0046666///retinal cell programmed cell death+++GO:0048087///positive regulation of developmental pigmentation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048515///spermatid differentiation+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0048678///response to axon injury+++GO:0048872///homeostasis of number of cells+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060011///Sertoli cell proliferation+++GO:0060041///retina development in camera-type eye+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060068///vagina development+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070242///thymocyte apoptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:0071310///cellular response to organic substance+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097296///activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097435///supramolecular fiber organization+++GO:0098586///cellular response to virus+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:1902512///positive regulation of apoptotic DNA fragmentation+++GO:1990117///B cell receptor apoptotic signaling pathway+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 12029 12029 'Bcl6b' mRNA 47 36 28 0.75 0.57 0.49 1.1 1.16 1.13 0.603333333 1.13 80 81 78 37 79.66666667 0.001175394 1.100324824 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001817///regulation of cytokine production+++GO:0002682///regulation of immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042092///type 2 immune response+++GO:0042127///regulation of cell proliferation+++GO:0045595///regulation of cell differentiation+++GO:0050727///regulation of inflammatory response 12032 12032 'Bcan' mRNA 45.1 38.98 29.99 0.62 0.6 0.55 0.12 0.18 0.11 0.59 0.136666667 12.65 14.22 8 38.02333333 11.62333333 0.001320486 -1.725012624 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane+++GO:0033268///node of Ranvier+++GO:0043194///axon initial segment+++GO:0045202///synapse+++GO:0072534///perineuronal net+++GO:0098966///perisynaptic extracellular matrix+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005509///calcium ion binding+++GO:0005540///hyaluronic acid binding+++GO:0030246///carbohydrate binding GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007417///central nervous system development+++GO:0021766///hippocampus development+++GO:0060074///synapse maturation+++GO:1990138///neuron projection extension 12033 12033 'Bcap29' mRNA 712 748 637 22.77 23.5 21.62 18.67 19.43 18.91 22.63 19.00333333 673 689 661 699 674.3333333 0.647599171 -0.060981331 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006915///apoptotic process+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0070973///protein localization to endoplasmic reticulum exit site 12034 12034 'Phb2' mRNA 1682 1739 1698 74.24 75.75 79.51 105.55 106.31 98.16 76.5 103.34 2746 2698 2470 1706.333333 2638 2.84E-17 0.616066206 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0035632///mitochondrial prohibitin complex+++GO:0048786///presynaptic active zone+++GO:0071944///cell periphery+++GO:0098800///inner mitochondrial membrane protein complex+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0033218///amide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046625///sphingolipid binding+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding "GO:0000423///mitophagy+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006606///protein import into nucleus+++GO:0007005///mitochondrion organization+++GO:0007062///sister chromatid cohesion+++GO:0007202///activation of phospholipase C activity+++GO:0009611///response to wounding+++GO:0016477///cell migration+++GO:0023035///CD40 signaling pathway+++GO:0031536///positive regulation of exit from mitosis+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0039520///induction by virus of host autophagy+++GO:0039529///RIG-I signaling pathway+++GO:0042113///B cell activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060749///mammary gland alveolus development+++GO:0060762///regulation of branching involved in mammary gland duct morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0071456///cellular response to hypoxia+++GO:1900208///regulation of cardiolipin metabolic process+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:1904959///regulation of cytochrome-c oxidase activity+++GO:1990051///activation of protein kinase C activity" 12035 12035 'Bcat1' mRNA 18 20 19 0.11 0.13 0.12 0.25 0.26 0.23 0.12 0.246666667 43 45 38 19 42 0.014354834 1.132820158 "00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00290///Valine, leucine and isoleucine biosynthesis+++00770///Pantothenate and CoA biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004084///branched-chain-amino-acid transaminase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0050048///L-leucine:2-oxoglutarate aminotransferase activity+++GO:0052654///L-leucine transaminase activity+++GO:0052655///L-valine transaminase activity+++GO:0052656///L-isoleucine transaminase activity GO:0008652///cellular amino acid biosynthetic process+++GO:0009081///branched-chain amino acid metabolic process+++GO:0009082///branched-chain amino acid biosynthetic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009098///leucine biosynthetic process+++GO:0009099///valine biosynthetic process 12036 12036 'Bcat2' mRNA 2307.01 2216 2347 74.7 70.77 80.66 69.4 74.3 73.57 75.37666667 72.42333333 2450 2563 2516 2290.003333 2509.666667 0.165864657 0.119065878 "00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00290///Valine, leucine and isoleucine biosynthesis+++00770///Pantothenate and CoA biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0004084///branched-chain-amino-acid transaminase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0050048///L-leucine:2-oxoglutarate aminotransferase activity+++GO:0052654///L-leucine transaminase activity+++GO:0052655///L-valine transaminase activity+++GO:0052656///L-isoleucine transaminase activity GO:0006549///isoleucine metabolic process+++GO:0006550///isoleucine catabolic process+++GO:0006551///leucine metabolic process+++GO:0006573///valine metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009081///branched-chain amino acid metabolic process+++GO:0009082///branched-chain amino acid biosynthetic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009098///leucine biosynthetic process+++GO:0009099///valine biosynthetic process+++GO:0010817///regulation of hormone levels+++GO:1990830///cellular response to leukemia inhibitory factor 12038 12038 'Bche' mRNA 277 335 242 2.36 2.81 2.19 1.83 1.7 1.7 2.453333333 1.743333333 247 224 223 284.6666667 231.3333333 0.084584855 -0.307029393 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005641///nuclear envelope lumen+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003990///acetylcholinesterase activity+++GO:0004104///cholinesterase activity+++GO:0016787///hydrolase activity+++GO:0033265///choline binding+++GO:0042802///identical protein binding+++GO:0052689///carboxylic ester hydrolase activity GO:0006581///acetylcholine catabolic process+++GO:0007584///response to nutrient+++GO:0007612///learning+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0014016///neuroblast differentiation+++GO:0019695///choline metabolic process+++GO:0042493///response to drug+++GO:0043279///response to alkaloid+++GO:0050805///negative regulation of synaptic transmission+++GO:0051384///response to glucocorticoid+++GO:0051593///response to folic acid 12039 12039 'Bckdha' mRNA 1390 1487 1439 46.53 50.05 52.05 41.23 39.79 40.09 49.54333333 40.37 1380 1315 1308 1438.666667 1334.333333 0.180759056 -0.121274255 "00280///Valine, leucine and isoleucine degradation+++00640///Propanoate metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex "GO:0003826///alpha-ketoacid dehydrogenase activity+++GO:0003863///3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding" GO:0009083///branched-chain amino acid catabolic process 12040 12040 'Bckdhb' mRNA 761.86 788.04 819.01 30.67 31.01 35.06 21.91 24.54 24.24 32.24666667 23.56333333 616 683.81 669.89 789.6366667 656.5666667 0.015798261 -0.279607467 "00280///Valine, leucine and isoleucine degradation+++00640///Propanoate metabolism" GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex GO:0003824///catalytic activity+++GO:0003826///alpha-ketoacid dehydrogenase activity+++GO:0003863///3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0044877///protein-containing complex binding GO:0007584///response to nutrient+++GO:0009063///cellular amino acid catabolic process+++GO:0009083///branched-chain amino acid catabolic process 12041 12041 'Bckdk' mRNA 2416.83 2513.5 2399.36 46.63 47.73 49.11 39.27 40.3 39.87 47.82333333 39.81333333 2341.63 2346.84 2302.03 2443.23 2330.166667 0.306267126 -0.080027661 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0047323///[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity" GO:0006468///protein phosphorylation+++GO:0006550///isoleucine catabolic process+++GO:0006552///leucine catabolic process+++GO:0006574///valine catabolic process+++GO:0007283///spermatogenesis+++GO:0009083///branched-chain amino acid catabolic process+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation 12042 12042 'Bcl10' mRNA 676 702 655 19.69 20.15 20.24 29.72 26.92 26.31 20.02666667 27.65 1173 1037 1005 677.6666667 1071.666667 8.70E-12 0.648860655 04064///NF-kappa B signaling pathway+++04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++05131///Shigellosis+++05152///Tuberculosis GO:0001772///immunological synapse+++GO:0002096///polkadots+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0032449///CBM complex+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0019209///kinase activator activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043422///protein kinase B binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0050700///CARD domain binding+++GO:0051059///NF-kappaB binding "GO:0001783///B cell apoptotic process+++GO:0001819///positive regulation of cytokine production+++GO:0001843///neural tube closure+++GO:0002224///toll-like receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006968///cellular defense response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0008219///cell death+++GO:0009620///response to fungus+++GO:0016064///immunoglobulin mediated immune response+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032094///response to food+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033674///positive regulation of kinase activity+++GO:0042327///positive regulation of phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0044346///fibroblast apoptotic process+++GO:0045087///innate immune response+++GO:0045576///mast cell activation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050852///T cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization+++GO:0061760///antifungal innate immune response+++GO:0070231///T cell apoptotic process+++GO:0070242///thymocyte apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 12043 12043 'Bcl2' mRNA 1876 1947 1667 18.74 19.99 17.01 7.43 8.02 7.76 18.58 7.736666667 920 917 880 1830 905.6666667 8.49E-40 -1.024110823 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04071///Sphingolipid signaling pathway+++04115///p53 signaling pathway+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04261///Adrenergic signaling in cardiomyocytes+++04340///Hedgehog signaling pathway+++04510///Focal adhesion+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04915///Estrogen signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04933///AGE-RAGE signaling pathway in diabetic complications+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05132///Salmonella infection+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05215///Prostate cancer+++05222///Small cell lung cancer+++05226///Gastric cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031965///nuclear membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0046930///pore complex+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0015267///channel activity+++GO:0016248///channel inhibitor activity+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051400///BH domain binding+++GO:0051434///BH3 domain binding+++GO:0051721///protein phosphatase 2A binding "GO:0000209///protein polyubiquitination+++GO:0000902///cell morphogenesis+++GO:0001101///response to acid chemical+++GO:0001503///ossification+++GO:0001541///ovarian follicle development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001662///behavioral fear response+++GO:0001776///leukocyte homeostasis+++GO:0001782///B cell homeostasis+++GO:0001822///kidney development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002260///lymphocyte homeostasis+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0002326///B cell lineage commitment+++GO:0002360///T cell lineage commitment+++GO:0002520///immune system development+++GO:0002931///response to ischemia+++GO:0003014///renal system process+++GO:0006470///protein dephosphorylation+++GO:0006582///melanin metabolic process+++GO:0006808///regulation of nitrogen utilization+++GO:0006874///cellular calcium ion homeostasis+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007015///actin filament organization+++GO:0007409///axonogenesis+++GO:0007569///cell aging+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0008637///apoptotic mitochondrial changes+++GO:0009410///response to xenobiotic stimulus+++GO:0009636///response to toxic substance+++GO:0009791///post-embryonic development+++GO:0009887///animal organ morphogenesis+++GO:0010039///response to iron ion+++GO:0010224///response to UV-B+++GO:0010332///response to gamma radiation+++GO:0010468///regulation of gene expression+++GO:0010506///regulation of autophagy+++GO:0010507///negative regulation of autophagy+++GO:0010523///negative regulation of calcium ion transport into cytosol+++GO:0010559///regulation of glycoprotein biosynthetic process+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0014031///mesenchymal cell development+++GO:0014042///positive regulation of neuron maturation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021747///cochlear nucleus development+++GO:0022612///gland morphogenesis+++GO:0022898///regulation of transmembrane transporter activity+++GO:0030097///hemopoiesis+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0030318///melanocyte differentiation+++GO:0030336///negative regulation of cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031069///hair follicle morphogenesis+++GO:0031103///axon regeneration+++GO:0031647///regulation of protein stability+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032835///glomerulus development+++GO:0032848///negative regulation of cellular pH reduction+++GO:0032880///regulation of protein localization+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0033077///T cell differentiation in thymus+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0034097///response to cytokine+++GO:0035094///response to nicotine+++GO:0035265///organ growth+++GO:0040008///regulation of growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042100///B cell proliferation+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043067///regulation of programmed cell death+++GO:0043085///positive regulation of catalytic activity+++GO:0043375///CD8-positive, alpha-beta T cell lineage commitment+++GO:0043473///pigmentation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043583///ear development+++GO:0045069///regulation of viral genome replication+++GO:0045471///response to ethanol+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0046671///negative regulation of retinal cell programmed cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048041///focal adhesion assembly+++GO:0048066///developmental pigmentation+++GO:0048070///regulation of developmental pigmentation+++GO:0048087///positive regulation of developmental pigmentation+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048545///response to steroid hormone+++GO:0048546///digestive tract morphogenesis+++GO:0048589///developmental growth+++GO:0048599///oocyte development+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0048753///pigment granule organization+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050790///regulation of catalytic activity+++GO:0050853///B cell receptor signaling pathway+++GO:0051384///response to glucocorticoid+++GO:0051402///neuron apoptotic process+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051924///regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071310///cellular response to organic substance+++GO:0071456///cellular response to hypoxia+++GO:0072593///reactive oxygen species metabolic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0098609///cell-cell adhesion+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000811///negative regulation of anoikis+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 12044 12044 'Bcl2a1a' mRNA 9.32 10.35 6.07 0.8 0.88 0.55 21.61 24.03 23.06 0.743333333 22.9 288.59 312.44 297.21 8.58 299.4133333 1.12E-50 5.156817759 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051400///BH domain binding GO:0001782///B cell homeostasis+++GO:0002903///negative regulation of B cell apoptotic process+++GO:0006915///apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 12045 12045 'Bcl2a1b' mRNA 43.37 48.76 59.89 3.93 4.38 5.76 155.09 162.43 168.74 4.69 162.0866667 1959.38 1997.69 2057.65 50.67333333 2004.906667 7.15E-290 5.313082355 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005741///mitochondrial outer membrane GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051400///BH domain binding GO:0006915///apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 12046 12046 'Bcl2a1c' mRNA 1 1 0 0.21 0.21 0 5.87 2.56 6.64 0.14 5.023333333 32 13.51 34.81 0.666666667 26.77333333 2.99E-05 5.29355348 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005741///mitochondrial outer membrane GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0006915///apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 12047 12047 'Bcl2a1d' mRNA 21.31 16.88 20.04 1.83 1.43 1.82 33.11 34.64 36.02 1.693333333 34.59 442.04 450.37 464.34 19.41 452.25 2.00E-78 4.560911561 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005741///mitochondrial outer membrane GO:0042803///protein homodimerization activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051400///BH domain binding GO:0006915///apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0030217///T cell differentiation+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050852///T cell receptor signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 12048 12048 'Bcl2l1' mRNA 6609 7203 7158 146.45 156.77 168.53 134.76 142.1 136.03 157.25 137.63 6946 7146 6788 6990 6960 0.847617432 -0.019260685 01521///EGFR tyrosine kinase inhibitor resistance+++01524///Platinum drug resistance+++04014///Ras signaling pathway+++04064///NF-kappa B signaling pathway+++04115///p53 signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05145///Toxoplasmosis+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05225///Hepatocellular carcinoma+++05417///Lipid and atherosclerosis GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0031966///mitochondrial membrane+++GO:0045202///synapse+++GO:0097136///Bcl-2 family protein complex+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051020///GTPase binding+++GO:0051400///BH domain binding+++GO:0051434///BH3 domain binding+++GO:0097371///MDM2/MDM4 family protein binding GO:0001541///ovarian follicle development+++GO:0001701///in utero embryonic development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0002931///response to ischemia+++GO:0006915///apoptotic process+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009314///response to radiation+++GO:0009566///fertilization+++GO:0009615///response to virus+++GO:0019050///suppression by virus of host apoptotic process+++GO:0032465///regulation of cytokinesis+++GO:0034097///response to cytokine+++GO:0036466///synaptic vesicle recycling via endosome+++GO:0040008///regulation of growth+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046898///response to cycloheximide+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0051402///neuron apoptotic process+++GO:0051607///defense response to virus+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070584///mitochondrion morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071312///cellular response to alkaloid+++GO:0071480///cellular response to gamma radiation+++GO:0071839///apoptotic process in bone marrow+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097284///hepatocyte apoptotic process+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1900452///regulation of long-term synaptic depression+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:2000811///negative regulation of anoikis+++GO:2001171///positive regulation of ATP biosynthetic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 12049 12049 'Bcl2l10' mRNA 0 1 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0044233///Mitochondria-associated ER Membrane GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0089720///caspase binding GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 12050 12050 'Bcl2l2' mRNA 896 867.47 886.04 23.41 21.02 24.66 22.5 20.3 23.19 23.03 21.99666667 984.69 880.51 1009.34 883.17 958.18 0.364061813 0.103811975 05206///MicroRNAs in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0097136///Bcl-2 family protein complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051400///BH domain binding+++GO:0097718///disordered domain specific binding GO:0002931///response to ischemia+++GO:0006915///apoptotic process+++GO:0007420///brain development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0060011///Sertoli cell proliferation+++GO:0071230///cellular response to amino acid stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1904646///cellular response to amyloid-beta+++GO:1905430///cellular response to glycine+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 12051 12051 'Bcl3' mRNA 146 122 99 4.6 3.8 3.34 10.36 8.94 11.13 3.913333333 10.14333333 379 319 393 122.3333333 363.6666667 1.11E-18 1.563337039 04625///C-type lectin receptor signaling pathway+++04668///TNF signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0032996///Bcl3-Bcl10 complex+++GO:0033257///Bcl3/NF-kappaB2 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030674///protein binding, bridging+++GO:0042826///histone deacetylase binding" "GO:0002268///follicular dendritic cell differentiation+++GO:0002315///marginal zone B cell differentiation+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0002467///germinal center formation+++GO:0006351///transcription, DNA-templated+++GO:0006606///protein import into nucleus+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0010225///response to UV-C+++GO:0019730///antimicrobial humoral response+++GO:0030198///extracellular matrix organization+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0042088///T-helper 1 type immune response+++GO:0042742///defense response to bacterium+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042832///defense response to protozoan+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045064///T-helper 2 cell differentiation+++GO:0045727///positive regulation of translation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048536///spleen development+++GO:0051101///regulation of DNA binding+++GO:1901222///regulation of NIK/NF-kappaB signaling" 12053 12053 'Bcl6' mRNA 195 174 198 2.96 2.55 3.19 4.56 2.25 4.18 2.9 3.663333333 347 162 300 189 269.6666667 0.049449518 0.492479322 04068///FoxO signaling pathway+++05202///Transcriptional misregulation in cancer+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001161///intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001817///regulation of cytokine production+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002376///immune system process+++GO:0002467///germinal center formation+++GO:0002682///regulation of immune system process+++GO:0002829///negative regulation of type 2 immune response+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007266///Rho protein signal transduction+++GO:0007283///spermatogenesis+++GO:0008104///protein localization+++GO:0008285///negative regulation of cell proliferation+++GO:0030036///actin cytoskeleton organization+++GO:0030183///B cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030890///positive regulation of B cell proliferation+++GO:0031065///positive regulation of histone deacetylation+++GO:0032764///negative regulation of mast cell cytokine production+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0042092///type 2 immune response+++GO:0042127///regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043087///regulation of GTPase activity+++GO:0043380///regulation of memory T cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045596///negative regulation of cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048294///negative regulation of isotype switching to IgE isotypes+++GO:0048821///erythrocyte development+++GO:0050727///regulation of inflammatory response+++GO:0051272///positive regulation of cellular component movement+++GO:2000773///negative regulation of cellular senescence" 12054 12054 'Bcl7b' mRNA 1494 1439 1325 52.2 49.57 49.12 38.04 40.78 36.93 50.29666667 38.58333333 1251 1309 1175 1419.333333 1245 0.024764295 -0.199070524 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation 12055 12055 'Bcl7c' mRNA 460 485 281.74 16.38 18.28 7.13 8.02 12.89 12.61 13.93 11.17333333 244 307 305 408.9133333 285.3333333 0.007092062 -0.517053674 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process 12057 12057 'Opn1sw' mRNA 57 59 41 1.32 1.35 1.01 0.44 0.62 0.33 1.226666667 0.463333333 22 30 16 52.33333333 22.66666667 0.00569898 -1.21057564 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm GO:0004930///G protein-coupled receptor activity+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009584///detection of visible light+++GO:0018298///protein-chromophore linkage+++GO:0050896///response to stimulus+++GO:0071482///cellular response to light stimulus+++GO:0071492///cellular response to UV-A 12061 12061 'Bdkrb1' mRNA 4 1 4 0.17 0.04 0.18 0.07 0 0.19 0.13 0.086666667 2 0 5 3 2.333333333 0.863090843 -0.391664077 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0004947///bradykinin receptor activity+++GO:0042277///peptide binding GO:0001933///negative regulation of protein phosphorylation+++GO:0002687///positive regulation of leukocyte migration+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0009612///response to mechanical stimulus+++GO:0016477///cell migration+++GO:0019233///sensory perception of pain+++GO:0030308///negative regulation of cell growth+++GO:0032496///response to lipopolysaccharide+++GO:0045776///negative regulation of blood pressure+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol 12062 12062 'Bdkrb2' mRNA 15 20 35 0.26 0.31 0.51 0.32 0.22 0.35 0.36 0.296666667 27 17 26 23.33333333 23.33333333 0.970792633 -0.030540809 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04961///Endocrine and other factor-regulated calcium reabsorption+++05142///Chagas disease+++05200///Pathways in cancer GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0002020///protease binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004947///bradykinin receptor activity+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0046982///protein heterodimerization activity GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008285///negative regulation of cell proliferation+++GO:0009651///response to salt stress+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042310///vasoconstriction+++GO:0042311///vasodilation+++GO:0045776///negative regulation of blood pressure+++GO:0050482///arachidonic acid secretion+++GO:1902219///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:1902239///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 12064 12064 'Bdnf' mRNA 3064 3277 3032 40.15 42.35 42.23 2.39 2.45 2.52 41.57666667 2.453333333 209 210 212 3124.333333 210.3333333 0 -3.904189916 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04722///Neurotrophin signaling pathway+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05034///Alcoholism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005788///endoplasmic reticulum lumen+++GO:0008021///synaptic vesicle+++GO:0016607///nuclear speck+++GO:0030061///mitochondrial crista+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0005102///signaling receptor binding+++GO:0005163///nerve growth factor receptor binding+++GO:0005169///neurotrophin TRKB receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity "GO:0001657///ureteric bud development+++GO:0001662///behavioral fear response+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007399///nervous system development+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007411///axon guidance+++GO:0007412///axon target recognition+++GO:0007416///synapse assembly+++GO:0007422///peripheral nervous system development+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0007631///feeding behavior+++GO:0008038///neuron recognition+++GO:0009410///response to xenobiotic stimulus+++GO:0010832///negative regulation of myotube differentiation+++GO:0010976///positive regulation of neuron projection development+++GO:0014047///glutamate secretion+++GO:0016358///dendrite development+++GO:0019222///regulation of metabolic process+++GO:0021675///nerve development+++GO:0030516///regulation of axon extension+++GO:0031099///regeneration+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038180///nerve growth factor signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0042493///response to drug+++GO:0042596///fear response+++GO:0043066///negative regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0046668///regulation of retinal cell programmed cell death+++GO:0048148///behavioral response to cocaine+++GO:0048167///regulation of synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048668///collateral sprouting+++GO:0048670///regulation of collateral sprouting+++GO:0048672///positive regulation of collateral sprouting+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0048839///inner ear development+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051965///positive regulation of synapse assembly+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0060548///negative regulation of cell death+++GO:0061193///taste bud development+++GO:0071229///cellular response to acid chemical+++GO:0097484///dendrite extension+++GO:0099083///retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission+++GO:1900122///positive regulation of receptor binding+++GO:1901215///negative regulation of neuron death+++GO:1990138///neuron projection extension+++GO:1990708///conditioned place preference+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway+++GO:2001234///negative regulation of apoptotic signaling pathway" 12068 12068 'Bet1' mRNA 582 679 665 23.39 26.92 28.36 34.19 36.48 32.2 26.22333333 34.29 977 1017 890 642 961.3333333 2.54E-07 0.569536031 04130///SNARE interactions in vesicular transport GO:0000137///Golgi cis cisterna+++GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0031201///SNARE complex+++GO:0031985///Golgi cisterna GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus 12069 12069 'Bex2' mRNA 1095.62 1034.06 1102.08 79.79 74.55 85.17 14.64 16.31 15.55 79.83666667 15.5 230.39 250.06 236.36 1077.253333 238.9366667 1.13E-81 -2.187036245 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0002052///positive regulation of neuroblast proliferation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0031103///axon regeneration+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0061564///axon development 12070 12070 'Bex3' mRNA 2378.23 2526.82 2415.72 166.16 174.79 179.04 141.2 159.55 148.06 173.33 149.6033333 2311.85 2543.78 2338.9 2440.256667 2398.176667 0.728867167 -0.036376104 04722///Neurotrophin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005102///signaling receptor binding+++GO:0005123///death receptor binding+++GO:0005163///nerve growth factor receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors 12075 12075 'Bfsp1' mRNA 15 15 11 0.37 0.37 0.36 0.35 0.46 0.28 0.366666667 0.363333333 13 17 11 13.66666667 13.66666667 0.998591786 -0.004700476 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding GO:0045109///intermediate filament organization+++GO:0048469///cell maturation+++GO:0070307///lens fiber cell development 12091 12091 'Glb1' mRNA 776.98 760.86 734.86 18.13 17.49 18.19 32.64 30.06 29.57 17.93666667 30.75666667 1608.3 1446.4 1410.58 757.5666667 1488.426667 1.96E-29 0.963207546 00052///Galactose metabolism+++00511///Other glycan degradation+++00531///Glycosaminoglycan degradation+++00600///Sphingolipid metabolism+++00604///Glycosphingolipid biosynthesis - ganglio series+++04142///Lysosome GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005773///vacuole+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004565///beta-galactosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016936///galactoside binding+++GO:0042803///protein homodimerization activity" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0019388///galactose catabolic process+++GO:0044262///cellular carbohydrate metabolic process+++GO:0051413///response to cortisone+++GO:1904016///response to Thyroglobulin triiodothyronine 12095 12095 'Bglap3' mRNA 52.68 55.92 54.29 5.08 5.37 5.36 65.71 82.74 70.86 5.27 73.10333333 773.9 944.86 802.88 54.29666667 840.5466667 4.18E-120 3.958183002 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005509///calcium ion binding+++GO:0008147///structural constituent of bone+++GO:0046848///hydroxyapatite binding+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0030500///regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0032571///response to vitamin K+++GO:0060348///bone development+++GO:1900076///regulation of cellular response to insulin stimulus 12096 12096 'Bglap' mRNA 26.53 21.8 22.04 4.83 3.98 4.26 3.98 4.53 5.16 4.356666667 4.556666667 24.81 27.41 30.94 23.45666667 27.72 0.737568214 0.221062818 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005509///calcium ion binding+++GO:0008147///structural constituent of bone+++GO:0046848///hydroxyapatite binding+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0030500///regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0032571///response to vitamin K+++GO:0060348///bone development+++GO:0071773///cellular response to BMP stimulus+++GO:1900076///regulation of cellular response to insulin stimulus 12097 12097 'Bglap2' mRNA 25.79 14.29 14.67 4.8 2.66 2.9 24.63 24.97 26.11 3.453333333 25.23666667 150.28 147.74 153.18 18.25 150.4 8.22E-22 3.076879872 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005509///calcium ion binding+++GO:0008147///structural constituent of bone+++GO:0046848///hydroxyapatite binding+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0030500///regulation of bone mineralization+++GO:0031016///pancreas development+++GO:0031214///biomineral tissue development+++GO:0032024///positive regulation of insulin secretion+++GO:0032571///response to vitamin K+++GO:0032869///cellular response to insulin stimulus+++GO:0042593///glucose homeostasis+++GO:0044242///cellular lipid catabolic process+++GO:0044342///type B pancreatic cell proliferation+++GO:0060348///bone development+++GO:1900076///regulation of cellular response to insulin stimulus 121021 121021 'Cspg4' mRNA 230 242 227 1.5 1.55 1.57 2.07 2.07 2.19 1.54 2.11 365 356 374 233 365 1.26E-05 0.636225039 GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0015026///coreceptor activity+++GO:0019901///protein kinase binding GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0006929///substrate-dependent cell migration+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0008347///glial cell migration+++GO:0010977///negative regulation of neuron projection development+++GO:0016322///neuron remodeling+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048771///tissue remodeling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0097178///ruffle assembly 121022 121022 'Mrps6' mRNA 6139.45 6111.1 5910.7 540.72 533.67 552.45 320.83 313.7 334.89 542.28 323.14 4168.44 3968.39 4200.4 6053.75 4112.41 1.10E-24 -0.569935462 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding+++GO:0070181///small ribosomal subunit rRNA binding GO:0006412///translation+++GO:0032543///mitochondrial translation 12111 12111 'Bgn' mRNA 1516 1590 1309 34.93 36.06 31.98 80.52 75.1 76.28 34.32333333 77.3 4018 3659 3685 1471.666667 3787.333333 8.43E-90 1.35426157 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0009986///cell surface+++GO:0030133///transport vesicle+++GO:0031012///extracellular matrix+++GO:0042383///sarcolemma+++GO:0062023///collagen-containing extracellular matrix GO:0005539///glycosaminoglycan binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0050840///extracellular matrix binding GO:0001974///blood vessel remodeling+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0060348///bone development+++GO:0061975///articular cartilage development 12116 12116 'Bhmt' mRNA 285 303 310 7.81 8.17 9.01 2.69 2.37 2.63 8.33 2.563333333 113 97 107 299.3333333 105.6666667 3.24E-17 -1.516640733 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047150///betaine-homocysteine S-methyltransferase activity GO:0006479///protein methylation+++GO:0006577///amino-acid betaine metabolic process+++GO:0006579///amino-acid betaine catabolic process+++GO:0009086///methionine biosynthetic process+++GO:0032259///methylation+++GO:0071267///L-methionine salvage 12121 12121 'Bicd1' mRNA 1347 1400 1195 16.65 16.47 15.33 10.51 9.17 9.57 16.15 9.75 976 823 854 1314 884.3333333 6.53E-11 -0.58196532 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0099503///secretory vesicle GO:0008093///cytoskeletal adaptor activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0031871///proteinase activated receptor binding+++GO:0034452///dynactin binding+++GO:0045505///dynein intermediate chain binding+++GO:0070840///dynein complex binding GO:0016032///viral process+++GO:0033365///protein localization to organelle+++GO:0034063///stress granule assembly+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0072385///minus-end-directed organelle transport along microtubule+++GO:0072393///microtubule anchoring at microtubule organizing center+++GO:1900275///negative regulation of phospholipase C activity+++GO:1900276///regulation of proteinase activated receptor activity+++GO:1900737///negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:1904781///positive regulation of protein localization to centrosome 12122 12122 'Bid' mRNA 149 134 168 4.47 3.99 5.39 14.43 15.27 14.39 4.616666667 14.69666667 552 572 536 150.3333333 553.3333333 1.34E-35 1.865063354 01524///Platinum drug resistance+++04071///Sphingolipid signaling pathway+++04115///p53 signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04650///Natural killer cell mediated cytotoxicity+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0032592///integral component of mitochondrial membrane GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0001836///release of cytochrome c from mitochondria+++GO:0002931///response to ischemia+++GO:0006626///protein targeting to mitochondrion+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007420///brain development+++GO:0008637///apoptotic mitochondrial changes+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0031334///positive regulation of protein complex assembly+++GO:0032355///response to estradiol+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0034349///glial cell apoptotic process+++GO:0042127///regulation of cell proliferation+++GO:0042770///signal transduction in response to DNA damage+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0065003///protein-containing complex assembly+++GO:0090150///establishment of protein localization to membrane+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:0097435///supramolecular fiber organization+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 12123 12123 'Hrk' mRNA 37 56 47 0.37 0.55 0.49 0.16 0.18 0.14 0.47 0.16 18 20 16 46.66666667 18 0.002456129 -1.385409768 04210///Apoptosis GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006915///apoptotic process+++GO:0031334///positive regulation of protein complex assembly+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0051365///cellular response to potassium ion starvation+++GO:0090200///positive regulation of release of cytochrome c from mitochondria 12124 12124 'Bik' mRNA 573 515 475 37.34 32.32 32.87 17.14 20.78 23.17 34.17666667 20.36333333 295 358 389 521 347.3333333 4.08E-05 -0.59282601 01522///Endocrine resistance GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0051400///BH domain binding GO:0002431///Fc receptor mediated stimulatory signaling pathway+++GO:0002513///tolerance induction to self antigen+++GO:0002576///platelet degranulation+++GO:0002902///regulation of B cell apoptotic process+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0008637///apoptotic mitochondrial changes+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0031175///neuron projection development+++GO:0031334///positive regulation of protein complex assembly+++GO:0032024///positive regulation of insulin secretion+++GO:0032092///positive regulation of protein binding+++GO:0043304///regulation of mast cell degranulation+++GO:0045087///innate immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0070667///negative regulation of mast cell proliferation+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090330///regulation of platelet aggregation+++GO:0097028///dendritic cell differentiation+++GO:2000670///positive regulation of dendritic cell apoptotic process 12125 12125 'Bcl2l11' mRNA 881.99 902.98 742 9.51 9.51 8.38 7.68 6.96 6.97 9.133333333 7.203333333 826.99 728.99 726 842.3233333 760.66 0.160663349 -0.156757349 01521///EGFR tyrosine kinase inhibitor resistance+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04932///Non-alcoholic fatty liver disease+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097136///Bcl-2 family protein complex+++GO:0097140///BIM-BCL-xl complex+++GO:0097141///BIM-BCL-2 complex GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0070840///dynein complex binding GO:0001701///in utero embryonic development+++GO:0001776///leukocyte homeostasis+++GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001822///kidney development+++GO:0002260///lymphocyte homeostasis+++GO:0002262///myeloid cell homeostasis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007127///meiosis I+++GO:0007160///cell-matrix adhesion+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0008584///male gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009791///post-embryonic development+++GO:0010942///positive regulation of cell death+++GO:0030879///mammary gland development+++GO:0031334///positive regulation of protein complex assembly+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035148///tube formation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043583///ear development+++GO:0045787///positive regulation of cell cycle+++GO:0046620///regulation of organ growth+++GO:0048066///developmental pigmentation+++GO:0048070///regulation of developmental pigmentation+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0060139///positive regulation of apoptotic process by virus+++GO:0070242///thymocyte apoptotic process+++GO:0071392///cellular response to estradiol stimulus+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:1904646///cellular response to amyloid-beta+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 12140 12140 'Fabp7' mRNA 531 467 518 48.26 42.09 49.96 32.65 35.09 31.52 46.77 33.08666667 411 430 383 505.3333333 408 0.01908817 -0.322046499 03320///PPAR signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0071944///cell periphery GO:0005504///fatty acid binding+++GO:0008289///lipid binding GO:0001964///startle response+++GO:0015908///fatty acid transport+++GO:0021846///cell proliferation in forebrain+++GO:0022008///neurogenesis+++GO:0050673///epithelial cell proliferation+++GO:0060134///prepulse inhibition 12142 12142 'Prdm1' mRNA 13 22 19 0.13 0.21 0.2 0.75 0.72 0.8 0.18 0.756666667 87 80 91 18 86 1.49E-09 2.243994356 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001763///morphogenesis of a branching structure+++GO:0001822///kidney development+++GO:0001892///embryonic placenta development+++GO:0001893///maternal placenta development+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0003170///heart valve development+++GO:0003279///cardiac septum development+++GO:0003281///ventricular septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030889///negative regulation of B cell proliferation+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032259///methylation+++GO:0032823///regulation of natural killer cell differentiation+++GO:0033082///regulation of extrathymic T cell differentiation+++GO:0035904///aorta development+++GO:0042127///regulation of cell proliferation+++GO:0042462///eye photoreceptor cell development+++GO:0045087///innate immune response+++GO:0045165///cell fate commitment+++GO:0045579///positive regulation of B cell differentiation+++GO:0048844///artery morphogenesis+++GO:0048869///cellular developmental process+++GO:0051136///regulation of NK T cell differentiation+++GO:0060576///intestinal epithelial cell development+++GO:0060707///trophoblast giant cell differentiation+++GO:0060976///coronary vasculature development+++GO:1990654///sebum secreting cell proliferation 12143 12143 'Blk' mRNA 2 0 0 0.05 0 0 0.02 0.06 0.08 0.016666667 0.053333333 1 3 4 0.666666667 2.666666667 0.421000408 2.012801512 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0002431///Fc receptor mediated stimulatory signaling pathway+++GO:0002513///tolerance induction to self antigen+++GO:0002576///platelet degranulation+++GO:0002902///regulation of B cell apoptotic process+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0031175///neuron projection development+++GO:0032024///positive regulation of insulin secretion+++GO:0032092///positive regulation of protein binding+++GO:0043304///regulation of mast cell degranulation+++GO:0045087///innate immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0070667///negative regulation of mast cell proliferation+++GO:0090330///regulation of platelet aggregation+++GO:0097028///dendritic cell differentiation+++GO:2000670///positive regulation of dendritic cell apoptotic process 12144 12144 'Blm' mRNA 100 101 90 1.2 1.18 1.12 1.2 0.77 1.32 1.166666667 1.096666667 117 74 122 97 104.3333333 0.804045522 0.092382822 03440///Homologous recombination+++03460///Fanconi anemia pathway "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0000800///lateral element+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0045120///pronucleus" "GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0000403///Y-form DNA binding+++GO:0000405///bubble DNA binding+++GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008270///zinc ion binding+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0016887///ATPase activity+++GO:0036310///annealing helicase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0061749///forked DNA-dependent helicase activity+++GO:0061821///telomeric D-loop binding+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:1990814///DNA/DNA annealing activity" "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000729///DNA double-strand break processing+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010165///response to X-ray+++GO:0031297///replication fork processing+++GO:0032508///DNA duplex unwinding+++GO:0035690///cellular response to drug+++GO:0044237///cellular metabolic process+++GO:0044806///G-quadruplex DNA unwinding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045910///negative regulation of DNA recombination+++GO:0045950///negative regulation of mitotic recombination+++GO:0046632///alpha-beta T cell differentiation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0051098///regulation of binding+++GO:0051259///protein complex oligomerization+++GO:0051260///protein homooligomerization+++GO:0051276///chromosome organization+++GO:0051782///negative regulation of cell division+++GO:0061820///telomeric D-loop disassembly+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071479///cellular response to ionizing radiation+++GO:0072711///cellular response to hydroxyurea+++GO:0072757///cellular response to camptothecin+++GO:0090329///regulation of DNA-dependent DNA replication+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange" 12145 12145 'Cxcr5' mRNA 2 1 1 0.04 0.02 0.02 0.13 0.02 0.09 0.026666667 0.08 7 1 5 1.333333333 4.333333333 0.344940387 1.681829282 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0030595///leukocyte chemotaxis+++GO:0032467///positive regulation of cytokinesis+++GO:0042113///B cell activation+++GO:0048535///lymph node development+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 12151 12151 'Bmi1' mRNA 324 374 285 5.31 6.02 4.87 5.43 4.77 4.95 5.4 5.05 381 329 334 327.6666667 348 0.686091078 0.077839308 04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer GO:0000151///ubiquitin ligase complex+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0071535///RING-like zinc finger domain binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001701///in utero embryonic development+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006959///humoral immune response+++GO:0007420///brain development+++GO:0009987///cellular process+++GO:0010468///regulation of gene expression+++GO:0016573///histone acetylation+++GO:0016574///histone ubiquitination+++GO:0021903///rostrocaudal neural tube patterning+++GO:0030097///hemopoiesis+++GO:0030890///positive regulation of B cell proliferation+++GO:0031507///heterochromatin assembly+++GO:0033092///positive regulation of immature T cell proliferation in thymus+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0048103///somatic stem cell division+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0071347///cellular response to interleukin-1+++GO:0071549///cellular response to dexamethasone stimulus+++GO:2000011///regulation of adaxial/abaxial pattern formation+++GO:2001234///negative regulation of apoptotic signaling pathway" 12153 12153 'Bmp1' mRNA 199 260 231 2.9 3.7 3.58 10.35 10.24 9.84 3.393333333 10.14333333 816 785 749 230 783.3333333 1.04E-43 1.756071413 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0031982///vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0005125///cytokine activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0051216///cartilage development+++GO:0061036///positive regulation of cartilage development 12155 12155 'Bmp15' mRNA 6 11 9 0.11 0.19 0.17 0.18 0.11 0.22 0.156666667 0.17 12 7 14 8.666666667 11 0.752944406 0.329455286 04060///Cytokine-cytokine receptor interaction+++04913///Ovarian steroidogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0070698///type I activin receptor binding "GO:0001541///ovarian follicle development+++GO:0007165///signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060016///granulosa cell development+++GO:0060395///SMAD protein signal transduction" 12156 12156 'Bmp2' mRNA 1632 1626 1652 24.86 24.37 26.69 2.29 2.59 2.46 25.30666667 2.446666667 173 191 180 1636.666667 181.3333333 6.55E-193 -3.186594356 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070724///BMP receptor complex GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019211///phosphatase activator activity+++GO:0019904///protein domain specific binding+++GO:0039706///co-receptor binding+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046332///SMAD binding+++GO:0048018///receptor ligand activity+++GO:0070700///BMP receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0003130///BMP signaling pathway involved in heart induction+++GO:0003176///aortic valve development+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003210///cardiac atrium formation+++GO:0003272///endocardial cushion formation+++GO:0003308///negative regulation of Wnt signaling pathway involved in heart development+++GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0006029///proteoglycan metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0009790///embryo development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0010922///positive regulation of phosphatase activity+++GO:0021537///telencephalon development+++GO:0021978///telencephalon regionalization+++GO:0030154///cell differentiation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030282///bone mineralization+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031648///protein destabilization+++GO:0032092///positive regulation of protein binding+++GO:0032348///negative regulation of aldosterone biosynthetic process+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0035051///cardiocyte differentiation+++GO:0035054///embryonic heart tube anterior/posterior pattern specification+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0035630///bone mineralization involved in bone maturation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042482///positive regulation of odontogenesis+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0045165///cell fate commitment+++GO:0045597///positive regulation of cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048762///mesenchymal cell differentiation+++GO:0048839///inner ear development+++GO:0050769///positive regulation of neurogenesis+++GO:0051042///negative regulation of calcium-independent cell-cell adhesion+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0051216///cartilage development+++GO:0055007///cardiac muscle cell differentiation+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060039///pericardium development+++GO:0060128///corticotropin hormone secreting cell differentiation+++GO:0060129///thyroid-stimulating hormone-secreting cell differentiation+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060348///bone development+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0060485///mesenchyme development+++GO:0060804///positive regulation of Wnt signaling pathway by BMP signaling pathway+++GO:0061036///positive regulation of cartilage development+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071773///cellular response to BMP stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072138///mesenchymal cell proliferation involved in ureteric bud development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1905072///cardiac jelly development+++GO:1905222///atrioventricular canal morphogenesis+++GO:2000065///negative regulation of cortisol biosynthetic process+++GO:2000726///negative regulation of cardiac muscle cell differentiation" 12159 12159 'Bmp4' mRNA 138 160 139 3.8 4.37 4.2 3.84 4.05 4.43 4.123333333 4.106666667 160 165 176 145.6666667 167 0.431378526 0.18717057 04013///MAPK signaling pathway - fly+++04060///Cytokine-cytokine receptor interaction+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04919///Thyroid hormone signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031982///vesicle GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0039706///co-receptor binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0070700///BMP receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000186///activation of MAPKK activity+++GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001568///blood vessel development+++GO:0001649///osteoblast differentiation+++GO:0001654///eye development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001707///mesoderm formation+++GO:0001759///organ induction+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0001843///neural tube closure+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001936///regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001944///vasculature development+++GO:0001958///endochondral ossification+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0002062///chondrocyte differentiation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0003014///renal system process+++GO:0003130///BMP signaling pathway involved in heart induction+++GO:0003139///secondary heart field specification+++GO:0003148///outflow tract septum morphogenesis+++GO:0003149///membranous septum morphogenesis+++GO:0003150///muscular septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003197///endocardial cushion development+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003277///apoptotic process involved in endocardial cushion morphogenesis+++GO:0003323///type B pancreatic cell development+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007492///endoderm development+++GO:0007500///mesodermal cell fate determination+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0009888///tissue development+++GO:0009948///anterior/posterior axis specification+++GO:0010159///specification of animal organ position+++GO:0010453///regulation of cell fate commitment+++GO:0010468///regulation of gene expression+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010942///positive regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0021537///telencephalon development+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021978///telencephalon regionalization+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030224///monocyte differentiation+++GO:0030225///macrophage differentiation+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:0034504///protein localization to nucleus+++GO:0034599///cellular response to oxidative stress+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035990///tendon cell differentiation+++GO:0035993///deltoid tuberosity development+++GO:0042306///regulation of protein import into nucleus+++GO:0042326///negative regulation of phosphorylation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042476///odontogenesis+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045165///cell fate commitment+++GO:0045595///regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045786///negative regulation of cell cycle+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048333///mesodermal cell differentiation+++GO:0048392///intermediate mesodermal cell differentiation+++GO:0048593///camera-type eye morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048663///neuron fate commitment+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0048745///smooth muscle tissue development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050918///positive chemotaxis+++GO:0051145///smooth muscle cell differentiation+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:0051216///cartilage development+++GO:0055007///cardiac muscle cell differentiation+++GO:0055020///positive regulation of cardiac muscle fiber development+++GO:0060113///inner ear receptor cell differentiation+++GO:0060197///cloacal septation+++GO:0060235///lens induction in camera-type eye+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060348///bone development+++GO:0060363///cranial suture morphogenesis+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060393///regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0060425///lung morphogenesis+++GO:0060429///epithelium development+++GO:0060433///bronchus development+++GO:0060438///trachea development+++GO:0060440///trachea formation+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0060449///bud elongation involved in lung branching+++GO:0060502///epithelial cell proliferation involved in lung morphogenesis+++GO:0060503///bud dilation involved in lung branching+++GO:0060512///prostate gland morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060592///mammary gland formation+++GO:0060684///epithelial-mesenchymal cell signaling+++GO:0060686///negative regulation of prostatic bud formation+++GO:0060687///regulation of branching involved in prostate gland morphogenesis+++GO:0060688///regulation of morphogenesis of a branching structure+++GO:0060976///coronary vasculature development+++GO:0061035///regulation of cartilage development+++GO:0061036///positive regulation of cartilage development+++GO:0061047///positive regulation of branching involved in lung morphogenesis+++GO:0061149///BMP signaling pathway involved in ureter morphogenesis+++GO:0061151///BMP signaling pathway involved in renal system segmentation+++GO:0061155///pulmonary artery endothelial tube morphogenesis+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0070368///positive regulation of hepatocyte differentiation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0071893///BMP signaling pathway involved in nephric duct formation+++GO:0072015///glomerular visceral epithelial cell development+++GO:0072097///negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway+++GO:0072101///specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway+++GO:0072104///glomerular capillary formation+++GO:0072125///negative regulation of glomerular mesangial cell proliferation+++GO:0072138///mesenchymal cell proliferation involved in ureteric bud development+++GO:0072161///mesenchymal cell differentiation involved in kidney development+++GO:0072192///ureter epithelial cell differentiation+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0072198///mesenchymal cell proliferation involved in ureter development+++GO:0072200///negative regulation of mesenchymal cell proliferation involved in ureter development+++GO:0072205///metanephric collecting duct development+++GO:0090184///positive regulation of kidney development+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090191///negative regulation of branching involved in ureteric bud morphogenesis+++GO:0090194///negative regulation of glomerulus development+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901341///positive regulation of store-operated calcium channel activity+++GO:1901964///positive regulation of cell proliferation involved in outflow tract morphogenesis+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1905072///cardiac jelly development+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:2000005///negative regulation of metanephric S-shaped body morphogenesis+++GO:2000007///negative regulation of metanephric comma-shaped body morphogenesis+++GO:2000137///negative regulation of cell proliferation involved in heart morphogenesis+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2001012///mesenchymal cell differentiation involved in renal system development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 12160 12160 'Bmp5' mRNA 50 54 74 0.71 0.75 1.11 0.65 0.57 0.66 0.856666667 0.626666667 53 45 52 59.33333333 50 0.530614183 -0.267940658 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031982///vesicle GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0070700///BMP receptor binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0003272///endocardial cushion formation+++GO:0003323///type B pancreatic cell development+++GO:0003344///pericardium morphogenesis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0021502///neural fold elevation formation+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0030539///male genitalia development+++GO:0030902///hindbrain development+++GO:0032348///negative regulation of aldosterone biosynthetic process+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0043583///ear development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048738///cardiac muscle tissue development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0060037///pharyngeal system development+++GO:0060395///SMAD protein signal transduction+++GO:0060411///cardiac septum morphogenesis+++GO:0060710///chorio-allantoic fusion+++GO:0061384///heart trabecula morphogenesis+++GO:0097065///anterior head development+++GO:1900006///positive regulation of dendrite development+++GO:1905069///allantois development+++GO:2000065///negative regulation of cortisol biosynthetic process 12161 12161 'Bmp6' mRNA 363 313 392 6.66 5.65 7.62 2.41 2.58 2.53 6.643333333 2.506666667 151 158 154 356 154.3333333 1.39E-12 -1.221893001 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04913///Ovarian steroidogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031982///vesicle GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0046982///protein heterodimerization activity+++GO:0070700///BMP receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001654///eye development+++GO:0001822///kidney development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001958///endochondral ossification+++GO:0003323///type B pancreatic cell development+++GO:0006879///cellular iron ion homeostasis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0010039///response to iron ion+++GO:0010628///positive regulation of gene expression+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0014823///response to activity+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030539///male genitalia development+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0032026///response to magnesium ion+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032349///positive regulation of aldosterone biosynthetic process+++GO:0032526///response to retinoic acid+++GO:0043117///positive regulation of vascular permeability+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051216///cartilage development+++GO:0051384///response to glucocorticoid+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0071260///cellular response to mechanical stimulus+++GO:0071281///cellular response to iron ion+++GO:0071773///cellular response to BMP stimulus+++GO:1903392///negative regulation of adherens junction organization+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000860///positive regulation of aldosterone secretion 12162 12162 'Bmp7' mRNA 3177 3083 3034 46.95 44.82 47.56 30.65 30.07 33.22 46.44333333 31.31333333 2387 2288 2506 3098 2393.666667 1.53E-08 -0.384167221 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031982///vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0070700///BMP receptor binding "GO:0001503///ossification+++GO:0001654///eye development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001707///mesoderm formation+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0003272///endocardial cushion formation+++GO:0003344///pericardium morphogenesis+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007411///axon guidance+++GO:0007435///salivary gland morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010942///positive regulation of cell death+++GO:0021502///neural fold elevation formation+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0030902///hindbrain development+++GO:0032355///response to estradiol+++GO:0033280///response to vitamin D+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034504///protein localization to nucleus+++GO:0035239///tube morphogenesis+++GO:0042325///regulation of phosphorylation+++GO:0042326///negative regulation of phosphorylation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043434///response to peptide hormone+++GO:0045597///positive regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045786///negative regulation of cell cycle+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0048593///camera-type eye morphogenesis+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048738///cardiac muscle tissue development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048762///mesenchymal cell differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0051216///cartilage development+++GO:0060037///pharyngeal system development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060393///regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0060411///cardiac septum morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060485///mesenchyme development+++GO:0060548///negative regulation of cell death+++GO:0060686///negative regulation of prostatic bud formation+++GO:0060687///regulation of branching involved in prostate gland morphogenesis+++GO:0060710///chorio-allantoic fusion+++GO:0061384///heart trabecula morphogenesis+++GO:0070487///monocyte aggregation+++GO:0071773///cellular response to BMP stimulus+++GO:0072040///negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis+++GO:0072125///negative regulation of glomerular mesangial cell proliferation+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0072134///nephrogenic mesenchyme morphogenesis+++GO:0072136///metanephric mesenchymal cell proliferation involved in metanephros development+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:1900006///positive regulation of dendrite development+++GO:1900106///positive regulation of hyaluranon cable assembly+++GO:1905069///allantois development+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis" 12163 12163 'Bmp8a' mRNA 7 5 9 0.17 0.12 0.23 0.25 0.07 0.19 0.173333333 0.17 12 3.3 9 7 8.1 0.890221 0.162625168 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04714///Thermogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0070700///BMP receptor binding GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0002024///diet induced thermogenesis+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0046676///negative regulation of insulin secretion+++GO:0051216///cartilage development+++GO:0060395///SMAD protein signal transduction+++GO:0097009///energy homeostasis 12164 12164 'Bmp8b' mRNA 8 8 7 0.13 0.15 0.12 0.08 0.16 0.03 0.133333333 0.09 5 10.7 2 7.666666667 5.9 0.739263611 -0.440915718 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04714///Thermogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0070700///BMP receptor binding GO:0001503///ossification+++GO:0002024///diet induced thermogenesis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0048598///embryonic morphogenesis+++GO:0051216///cartilage development+++GO:0060395///SMAD protein signal transduction+++GO:0097009///energy homeostasis 12166 12166 'Bmpr1a' mRNA 1287 1299 1166 12.42 12.33 11.94 10.68 9.54 9.72 12.23 9.98 1269 1109 1123 1250.666667 1167 0.246498593 -0.111200709 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019211///phosphatase activator activity+++GO:0036122///BMP binding+++GO:0042803///protein homodimerization activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0098821///BMP receptor activity" GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0001756///somitogenesis+++GO:0001880///Mullerian duct regression+++GO:0001936///regulation of endothelial cell proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003161///cardiac conduction system development+++GO:0003171///atrioventricular valve development+++GO:0003183///mitral valve morphogenesis+++GO:0003186///tricuspid valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003272///endocardial cushion formation+++GO:0006468///protein phosphorylation+++GO:0006955///immune response+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007389///pattern specification process+++GO:0007398///ectoderm development+++GO:0007399///nervous system development+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0009950///dorsal/ventral axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010629///negative regulation of gene expression+++GO:0010665///regulation of cardiac muscle cell apoptotic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0014032///neural crest cell development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0019827///stem cell population maintenance+++GO:0021983///pituitary gland development+++GO:0021998///neural plate mediolateral regionalization+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0032915///positive regulation of transforming growth factor beta2 production+++GO:0035137///hindlimb morphogenesis+++GO:0035912///dorsal aorta morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0045601///regulation of endothelial cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048339///paraxial mesoderm development+++GO:0048352///paraxial mesoderm structural organization+++GO:0048368///lateral mesoderm development+++GO:0048378///regulation of lateral mesodermal cell fate specification+++GO:0048382///mesendoderm development+++GO:0048568///embryonic organ development+++GO:0048589///developmental growth+++GO:0048598///embryonic morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050768///negative regulation of neurogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0060896///neural plate pattern specification+++GO:0060914///heart formation+++GO:0060928///atrioventricular node cell development+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0071363///cellular response to growth factor stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904414///positive regulation of cardiac ventricle development+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905285///fibrous ring of heart morphogenesis+++GO:1905292///regulation of neural crest cell differentiation+++GO:1905295///regulation of neural crest cell fate specification+++GO:2000772///regulation of cellular senescence 12167 12167 'Bmpr1b' mRNA 787.57 795.61 758.07 7.43 7.55 7.81 5.57 5.36 5.6 7.596666667 5.51 666.16 622 640.8 780.4166667 642.9866667 0.004383815 -0.291317113 04013///MAPK signaling pathway - fly+++04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019211///phosphatase activator activity+++GO:0036122///BMP binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0098821///BMP receptor activity" GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0001550///ovarian cumulus expansion+++GO:0001649///osteoblast differentiation+++GO:0001654///eye development+++GO:0002062///chondrocyte differentiation+++GO:0002063///chondrocyte development+++GO:0006468///protein phosphorylation+++GO:0006703///estrogen biosynthetic process+++GO:0006954///inflammatory response+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0009953///dorsal/ventral pattern formation+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0030166///proteoglycan biosynthetic process+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035108///limb morphogenesis+++GO:0042698///ovulation cycle+++GO:0043010///camera-type eye development+++GO:0045597///positive regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0051216///cartilage development+++GO:0060041///retina development in camera-type eye+++GO:0060348///bone development+++GO:0060350///endochondral bone morphogenesis+++GO:0061036///positive regulation of cartilage development+++GO:0071363///cellular response to growth factor stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902731///negative regulation of chondrocyte proliferation 12168 12168 'Bmpr2' mRNA 1157 1181 1113 5.44 5.46 5.56 5.96 4.9 5.5 5.486666667 5.453333333 1457 1172 1305 1150.333333 1311.333333 0.071821583 0.175864613 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05206///MicroRNAs in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0005912///adherens junction+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019211///phosphatase activator activity+++GO:0019838///growth factor binding+++GO:0030546///receptor activator activity+++GO:0036122///BMP binding+++GO:0038023///signaling receptor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0098821///BMP receptor activity+++GO:1990782///protein tyrosine kinase binding GO:0001568///blood vessel development+++GO:0001649///osteoblast differentiation+++GO:0001707///mesoderm formation+++GO:0001893///maternal placenta development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001946///lymphangiogenesis+++GO:0001974///blood vessel remodeling+++GO:0002063///chondrocyte development+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003176///aortic valve development+++GO:0003177///pulmonary valve development+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003186///tricuspid valve morphogenesis+++GO:0003197///endocardial cushion development+++GO:0003252///negative regulation of cell proliferation involved in heart valve morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007420///brain development+++GO:0009267///cellular response to starvation+++GO:0009952///anterior/posterior pattern specification+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0014916///regulation of lung blood pressure+++GO:0016310///phosphorylation+++GO:0030166///proteoglycan biosynthetic process+++GO:0030308///negative regulation of cell growth+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045906///negative regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048738///cardiac muscle tissue development+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0050790///regulation of catalytic activity+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0060041///retina development in camera-type eye+++GO:0060173///limb development+++GO:0060350///endochondral bone morphogenesis+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0060413///atrial septum morphogenesis+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060840///artery development+++GO:0060841///venous blood vessel development+++GO:0061036///positive regulation of cartilage development+++GO:0061298///retina vasculature development in camera-type eye+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0071363///cellular response to growth factor stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072577///endothelial cell apoptotic process+++GO:1902731///negative regulation of chondrocyte proliferation+++GO:1905314///semi-lunar valve development+++GO:2000279///negative regulation of DNA biosynthetic process 12169 12169 'Bmx' mRNA 52 42 47 0.95 0.76 0.91 0.64 0.65 0.79 0.873333333 0.693333333 40 40 48 47 42.66666667 0.756037341 -0.151997177 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0002250///adaptive immune response+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0046777///protein autophosphorylation+++GO:0050853///B cell receptor signaling pathway 12173 12173 'Bnc1' mRNA 0 2 2 0 0.02 0.02 0.08 0.05 0.05 0.013333333 0.06 8 5 5 1.333333333 6 0.164367817 2.145896452 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000182///rDNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006356///regulation of transcription by RNA polymerase I+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0042060///wound healing+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051276///chromosome organization+++GO:1900195///positive regulation of oocyte maturation" 12175 12175 'Bnip2' mRNA 1967 2050 2171 43.97 45.09 50.49 74 75.07 74.67 46.51666667 74.58 3839 3837 3706 2062.666667 3794 6.81E-31 0.864925999 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0031616///spindle pole centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004309///exopolyphosphatase activity GO:0001824///blastocyst development+++GO:0006798///polyphosphate catabolic process+++GO:0006915///apoptotic process+++GO:0007098///centrosome cycle+++GO:0043410///positive regulation of MAPK cascade+++GO:0045666///positive regulation of neuron differentiation+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051146///striated muscle cell differentiation+++GO:0090649///response to oxygen-glucose deprivation 12176 12176 'Bnip3' mRNA 2622 2771 2854 86.33 89.92 99.68 45.86 47.78 46.66 91.97666667 46.76666667 1601 1628 1576 2749 1601.666667 2.07E-24 -0.793027117 04068///FoxO signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++05131///Shigellosis+++05134///Legionellosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031966///mitochondrial membrane GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051020///GTPase binding GO:0001666///response to hypoxia+++GO:0006915///apoptotic process+++GO:0008219///cell death+++GO:0009617///response to bacterium+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010821///regulation of mitochondrion organization+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0010940///positive regulation of necrotic cell death+++GO:0016239///positive regulation of macroautophagy+++GO:0021987///cerebral cortex development+++GO:0035694///mitochondrial protein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043067///regulation of programmed cell death+++GO:0043068///positive regulation of programmed cell death+++GO:0043243///positive regulation of protein complex disassembly+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045837///negative regulation of membrane potential+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048102///autophagic cell death+++GO:0048678///response to axon injury+++GO:0048709///oligodendrocyte differentiation+++GO:0050873///brown fat cell differentiation+++GO:0051402///neuron apoptotic process+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0051607///defense response to virus+++GO:0055093///response to hyperoxia+++GO:0060548///negative regulation of cell death+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071279///cellular response to cobalt ion+++GO:0071456///cellular response to hypoxia+++GO:0072593///reactive oxygen species metabolic process+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090649///response to oxygen-glucose deprivation+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:1901998///toxin transport+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:1903715///regulation of aerobic respiration+++GO:1990144///intrinsic apoptotic signaling pathway in response to hypoxia+++GO:2000378///negative regulation of reactive oxygen species metabolic process 12177 12177 'Bnip3l' mRNA 5377.59 5440.15 5250.05 90.61 90.14 93.91 77.3 75.83 72.11 91.55333333 75.08 5273.02 5055 4764 5355.93 5030.673333 0.11794824 -0.102661947 04137///Mitophagy - animal GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006915///apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0016239///positive regulation of macroautophagy+++GO:0035694///mitochondrial protein catabolic process+++GO:0035794///positive regulation of mitochondrial membrane permeability+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043067///regulation of programmed cell death+++GO:0051607///defense response to virus+++GO:0060548///negative regulation of cell death+++GO:0071456///cellular response to hypoxia+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903214///regulation of protein targeting to mitochondrion 12180 12180 'Smyd1' mRNA 0 3 0 0 0.05 0 0 0.03 0 0.016666667 0.01 0 2 0 1 0.666666667 0.895707484 -0.532941964 00310///Lysine degradation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0046872///metal ion binding "GO:0006338///chromatin remodeling+++GO:0007507///heart development+++GO:0010831///positive regulation of myotube differentiation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0035914///skeletal muscle cell differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 12181 12181 'Bop1' mRNA 955 922 1020 22.24 21.38 25.02 25.77 23.82 26.99 22.88 25.52666667 1305 1150 1319 965.6666667 1258 2.90E-04 0.366176191 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex+++GO:1990904///ribonucleoprotein complex" GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding "GO:0000027///ribosomal large subunit assembly+++GO:0000448///cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0008283///cell proliferation+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0051726///regulation of cell cycle+++GO:1901796///regulation of signal transduction by p53 class mediator" 12182 12182 'Bst1' mRNA 24 22 21 0.58 0.52 0.53 7.32 7.86 7.44 0.543333333 7.54 351 368 345 22.33333333 354.6666667 3.22E-61 3.979040201 00760///Nicotinate and nicotinamide metabolism+++04970///Salivary secretion+++04972///Pancreatic secretion GO:0001931///uropod+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031225///anchored component of membrane "GO:0003953///NAD+ nucleosidase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating+++GO:0061811///ADP-ribosyl cyclase activity+++GO:0061812///cyclic ADP-ribose hydrolase" GO:0001952///regulation of cell-matrix adhesion+++GO:0008284///positive regulation of cell proliferation+++GO:0030890///positive regulation of B cell proliferation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0050727///regulation of inflammatory response+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0090022///regulation of neutrophil chemotaxis 12183 12183 'Bpgm' mRNA 1102 1168 1151 40.98 42.84 45.46 27.8 30.06 28.72 43.09333333 28.86 853 899 859 1140.333333 870.3333333 1.85E-05 -0.401973399 "00010///Glycolysis / Gluconeogenesis+++00260///Glycine, serine and threonine metabolism" "GO:0003824///catalytic activity+++GO:0004082///bisphosphoglycerate mutase activity+++GO:0004619///phosphoglycerate mutase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases" GO:0006096///glycolytic process+++GO:0048821///erythrocyte development 12189 12189 'Brca1' mRNA 42 40 49 0.44 0.5 0.62 1.21 1.08 0.75 0.52 1.013333333 144 109 86 43.66666667 113 1.26E-05 1.352873112 01524///Platinum drug resistance+++03440///Homologous recombination+++03460///Fanconi anemia pathway+++04120///Ubiquitin mediated proteolysis+++04151///PI3K-Akt signaling pathway+++05206///MicroRNAs in cancer+++05224///Breast cancer GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0031436///BRCA1-BARD1 complex+++GO:0032991///protein-containing complex+++GO:0070531///BRCA1-A complex+++GO:1990904///ribonucleoprotein complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070063///RNA polymerase binding "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006301///postreplication repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007098///centrosome cycle+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010212///response to ionizing radiation+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035066///positive regulation of histone acetylation+++GO:0035067///negative regulation of histone acetylation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043009///chordate embryonic development+++GO:0043627///response to estrogen+++GO:0044030///regulation of DNA methylation+++GO:0044818///mitotic G2/M transition checkpoint+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0045739///positive regulation of DNA repair+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051298///centrosome duplication+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0051726///regulation of cell cycle+++GO:0051865///protein autoubiquitination+++GO:0070512///positive regulation of histone H4-K20 methylation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071681///cellular response to indole-3-methanol+++GO:0085020///protein K6-linked ubiquitination+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:2000620///positive regulation of histone H4-K16 acetylation" 12190 12190 'Brca2' mRNA 226 169 178 1.06 0.78 0.89 0.75 0.79 0.77 0.91 0.77 183 190 182 191 185 0.839303607 -0.056740536 03440///Homologous recombination+++03460///Fanconi anemia pathway+++05200///Pathways in cancer+++05212///Pancreatic cancer+++05224///Breast cancer "GO:0000781///chromosome, telomeric region+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0033593///BRCA2-MAGE-D1 complex" GO:0002020///protease binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0010484///H3 histone acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding "GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001556///oocyte maturation+++GO:0001833///inner cell mass cell proliferation+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0007569///cell aging+++GO:0008283///cell proliferation+++GO:0008585///female gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010165///response to X-ray+++GO:0010225///response to UV-C+++GO:0010332///response to gamma radiation+++GO:0030097///hemopoiesis+++GO:0030879///mammary gland development+++GO:0031619///homologous chromosome orientation involved in meiotic metaphase I plate congression+++GO:0032465///regulation of cytokinesis+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0035264///multicellular organism growth+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043009///chordate embryonic development+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0048478///replication fork protection+++GO:0051276///chromosome organization+++GO:0051298///centrosome duplication+++GO:0070200///establishment of protein localization to telomere+++GO:1990426///mitotic recombination-dependent replication fork processing" 12192 12192 'Zfp36l1' mRNA 3638 3598 3102 66.99 65.2 60.6 72.66 82.17 76.66 64.26333333 77.16333333 4540 5014 4638 3446 4730.666667 8.68E-11 0.449189503 04218///Cellular senescence GO:0000126///transcription factor TFIIIB complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097550///transcriptional preinitiation complex+++GO:1990904///ribonucleoprotein complex GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0017025///TBP-class protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding "GO:0000165///MAPK cascade+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0001570///vasculogenesis+++GO:0003342///proepicardium development+++GO:0006352///DNA-templated transcription, initiation+++GO:0006383///transcription by RNA polymerase III+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0010837///regulation of keratinocyte proliferation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0021915///neural tube development+++GO:0031086///nuclear-transcribed mRNA catabolic process, deadenylation-independent decay+++GO:0031440///regulation of mRNA 3'-end processing+++GO:0032869///cellular response to insulin stimulus+++GO:0033077///T cell differentiation in thymus+++GO:0035264///multicellular organism growth+++GO:0038066///p38MAPK cascade+++GO:0043488///regulation of mRNA stability+++GO:0043491///protein kinase B signaling+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045577///regulation of B cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045616///regulation of keratinocyte differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045661///regulation of myoblast differentiation+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0048382///mesendoderm development+++GO:0048568///embryonic organ development+++GO:0051028///mRNA transport+++GO:0060710///chorio-allantoic fusion+++GO:0060712///spongiotrophoblast layer development+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070897///transcription preinitiation complex assembly+++GO:0071320///cellular response to cAMP+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071472///cellular response to salt stress+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0072091///regulation of stem cell proliferation+++GO:0097403///cellular response to raffinose+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901991///negative regulation of mitotic cell cycle phase transition+++GO:1902172///regulation of keratinocyte apoptotic process+++GO:1904582///positive regulation of intracellular mRNA localization" 12193 12193 'Zfp36l2' mRNA 1382 1355 642 21.24 20.48 10.46 15.45 17.81 18.5 17.39333333 17.25333333 1157 1303 1342 1126.333333 1267.333333 0.691714189 0.176320244 04218///Cellular senescence GO:0000126///transcription factor TFIIIB complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0097550///transcriptional preinitiation complex GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0017025///TBP-class protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0046872///metal ion binding "GO:0000165///MAPK cascade+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0006352///DNA-templated transcription, initiation+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0006402///mRNA catabolic process+++GO:0007275///multicellular organism development+++GO:0009611///response to wounding+++GO:0030097///hemopoiesis+++GO:0033077///T cell differentiation in thymus+++GO:0034599///cellular response to oxidative stress+++GO:0035019///somatic stem cell population maintenance+++GO:0043488///regulation of mRNA stability+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045577///regulation of B cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0048103///somatic stem cell division+++GO:0060216///definitive hemopoiesis+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070897///transcription preinitiation complex assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901991///negative regulation of mitotic cell cycle phase transition+++GO:2000737///negative regulation of stem cell differentiation" 12211 12211 'Birc6' mRNA 2000 1782 1766 6.6 5.79 6.19 6.16 5.92 6.21 6.193333333 6.096666667 2149 2022 2097 1849.333333 2089.333333 0.040854221 0.164315388 04120///Ubiquitin mediated proteolysis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0090543///Flemming body GO:0004842///ubiquitin-protein transferase activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030414///peptidase inhibitor activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0001890///placenta development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016567///protein ubiquitination+++GO:0032465///regulation of cytokinesis+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0051301///cell division+++GO:0060711///labyrinthine layer development+++GO:0060712///spongiotrophoblast layer development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 12212 12212 'Chic1' mRNA 638.09 662.96 520.36 8.6 9.38 7.28 6.83 5.75 7.04 8.42 6.54 703.11 570.58 615.83 607.1366667 629.84 0.788695373 0.043623751 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function 12215 12215 'Bsg' mRNA 25240 26164 25084 1027.04 1049.76 1081.99 1094.86 1143.35 1123.03 1052.93 1120.413333 30252 30810 29983 25496 30348.33333 3.38E-06 0.239615192 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0002080///acrosomal membrane+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030424///axon+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0098632///cell-cell adhesion mediator activity GO:0001525///angiogenesis+++GO:0003407///neural retina development+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007283///spermatogenesis+++GO:0007411///axon guidance+++GO:0007566///embryo implantation+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010595///positive regulation of endothelial cell migration+++GO:0030154///cell differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043434///response to peptide hormone+++GO:0045494///photoreceptor cell maintenance+++GO:0046598///positive regulation of viral entry into host cell+++GO:0046689///response to mercury ion+++GO:0046697///decidualization+++GO:0046718///viral entry into host cell+++GO:0051591///response to cAMP+++GO:0061154///endothelial tube morphogenesis+++GO:0070593///dendrite self-avoidance+++GO:0072659///protein localization to plasma membrane+++GO:1904466///positive regulation of matrix metallopeptidase secretion 12217 12217 'Bsn' mRNA 179 217 175.03 0.58 0.67 0.58 0.15 0.14 0.18 0.61 0.156666667 55.73 52.07 66 190.3433333 57.93333333 9.97E-14 -1.731844343 GO:0005737///cytoplasm+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0060077///inhibitory synapse+++GO:0097060///synaptic membrane+++GO:0097470///ribbon synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:1904115///axon cytoplasm+++GO:1990257///piccolo-bassoon transport vesicle GO:0001222///transcription corepressor binding+++GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0046872///metal ion binding+++GO:0098882///structural constituent of presynaptic active zone GO:0007416///synapse assembly+++GO:0008088///axo-dendritic transport+++GO:0008090///retrograde axonal transport+++GO:0035418///protein localization to synapse+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0050808///synapse organization+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0099526///presynapse to nucleus signaling pathway+++GO:1904071///presynaptic active zone assembly+++GO:1904666///regulation of ubiquitin protein ligase activity 12223 12223 'Btc' mRNA 173 207 217 3.31 3.9 4.41 1.7 2.03 2.24 3.873333333 1.99 102 119 130 199 117 3.51E-04 -0.779786267 04012///ErbB signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005154///epidermal growth factor receptor binding+++GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0035810///positive regulation of urine volume+++GO:0043066///negative regulation of apoptotic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051781///positive regulation of cell division 12224 12224 'Klf5' mRNA 1126 1092 276 37.75 36.09 9.82 5.92 6.64 8.59 27.88666667 7.05 203 222 285 831.3333333 236.6666667 0.004174429 -1.796315296 05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043426///MRF binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0014901///satellite cell activation involved in skeletal muscle regeneration+++GO:0014908///myotube differentiation involved in skeletal muscle regeneration+++GO:0030033///microvillus assembly+++GO:0032534///regulation of microvillus assembly+++GO:0035914///skeletal muscle cell differentiation+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060576///intestinal epithelial cell development+++GO:0061586///positive regulation of transcription by transcription factor localization+++GO:0071407///cellular response to organic cyclic compound+++GO:0099156///cell-cell signaling via exosome+++GO:1901653///cellular response to peptide+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000723///negative regulation of cardiac vascular smooth muscle cell differentiation" 12226 12226 'Btg1' mRNA 1549 1472 874 16.52 15.43 9.89 12.99 12.73 14.1 13.94666667 13.27333333 1402 1343 1474.64 1298.333333 1406.546667 0.713003394 0.115343753 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0006479///protein methylation+++GO:0006979///response to oxidative stress+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0043085///positive regulation of catalytic activity+++GO:0043434///response to peptide hormone+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045930///negative regulation of mitotic cell cycle+++GO:2000271///positive regulation of fibroblast apoptotic process 12227 12227 'Btg2' mRNA 820 884 916 14.58 15.47 17.28 25.21 25.38 25.51 15.77666667 25.36666667 1631 1604 1598 873.3333333 1611 1.11E-22 0.869522697 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003714///transcription corepressor activity+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006479///protein methylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008285///negative regulation of cell proliferation+++GO:0008306///associative learning+++GO:0009612///response to mechanical stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0010033///response to organic substance+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0017148///negative regulation of translation+++GO:0021542///dentate gyrus development+++GO:0021954///central nervous system neuron development+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0035914///skeletal muscle cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051602///response to electrical stimulus+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:2000178///negative regulation of neural precursor cell proliferation 12228 12228 'Btg3' mRNA 334 324 180 15.66 14.99 9.12 8.8 8.89 10.19 13.25666667 9.293333333 213 200 247 279.3333333 220 0.132037043 -0.344460321 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0008285///negative regulation of cell proliferation+++GO:0045930///negative regulation of mitotic cell cycle 12229 12229 'Btk' mRNA 17 10 12 0.37 0.22 0.28 7.93 7.52 7.31 0.29 7.586666667 416 385 371 13 390.6666667 7.21E-67 4.897843528 04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04611///Platelet activation+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0046872///metal ion binding" GO:0001805///positive regulation of type III hypersensitivity+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0001818///negative regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002344///B cell affinity maturation+++GO:0002376///immune system process+++GO:0002553///histamine secretion by mast cell+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010033///response to organic substance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030889///negative regulation of B cell proliferation+++GO:0034614///cellular response to reactive oxygen species+++GO:0035556///intracellular signal transduction+++GO:0045087///innate immune response+++GO:0046777///protein autophosphorylation+++GO:0048469///cell maturation+++GO:0050790///regulation of catalytic activity+++GO:0050853///B cell receptor signaling pathway+++GO:0071226///cellular response to molecule of fungal origin+++GO:0098761///cellular response to interleukin-7 12231 12231 'Btn1a1' mRNA 2 0 0 0.03 0 0 0.07 0.1 0.08 0.01 0.083333333 5 7 6 0.666666667 6 0.07503524 3.172795702 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0001817///regulation of cytokine production+++GO:0001818///negative regulation of cytokine production+++GO:0031324///negative regulation of cellular metabolic process+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050852///T cell receptor signaling pathway 12234 12234 'Btrc' mRNA 1314 1427 1316 10.99 11.71 11.67 6.47 6.45 6.33 11.45666667 6.416666667 889 869 842 1352.333333 866.6666667 9.03E-15 -0.653406714 04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04390///Hippo signaling pathway+++04624///Toll and Imd signaling pathway+++04710///Circadian rhythm+++05131///Shigellosis+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex "GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0045309///protein phosphorylated amino acid binding+++GO:0046983///protein dimerization activity+++GO:0061630///ubiquitin protein ligase activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination+++GO:1990757///ubiquitin ligase activator activity" "GO:0000209///protein polyubiquitination+++GO:0006470///protein dephosphorylation+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031648///protein destabilization+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0042752///regulation of circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045862///positive regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0071407///cellular response to organic cyclic compound+++GO:1904668///positive regulation of ubiquitin protein ligase activity" 12235 12235 'Bub1' mRNA 4 0 3 0.05 0 0.04 1.81 1.77 2.07 0.03 1.883333333 168 160 186 2.333333333 171.3333333 2.36E-24 6.18603049 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007063///regulation of sister chromatid cohesion+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0008283///cell proliferation+++GO:0016310///phosphorylation+++GO:0051301///cell division+++GO:0051754///meiotic sister chromatid cohesion, centromeric+++GO:0051983///regulation of chromosome segregation+++GO:0071174///mitotic spindle checkpoint+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 12236 12236 'Bub1b' mRNA 23 26 23 0.34 0.38 0.36 4.82 4.05 4.18 0.36 4.35 375 308 315 24 332.6666667 5.11E-55 3.780549943 04110///Cell cycle+++05166///Human T-cell leukemia virus 1 infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0016310///phosphorylation+++GO:0051301///cell division+++GO:0051754///meiotic sister chromatid cohesion, centromeric+++GO:0071459///protein localization to chromosome, centromeric region" 12237 12237 'Bub3' mRNA 5582 5666 5425 153.08 152.98 157.73 136.22 142.08 132.38 154.5966667 136.8933333 5713 5818 5374 5557.666667 5635 0.916747509 0.008361447 04110///Cell cycle+++05166///Human T-cell leukemia virus 1 infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0033597///mitotic checkpoint complex+++GO:1990298///bub1-bub3 complex" GO:0043130///ubiquitin binding GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051983///regulation of chromosome segregation 12238 12238 'Commd3' mRNA 1064 1035 1089 75.24 72.44 81.72 111.15 117.43 113.9 76.46666667 114.16 1801 1854 1783 1062.666667 1812.666667 6.16E-20 0.757441838 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008150///biological_process 12257 12257 'Tspo' mRNA 3779 3865 3611 294.43 298.25 298.55 480.23 495.81 479 297.0766667 485.0133333 7059 7099 6800 3751.666667 6986 7.36E-60 0.885885018 04080///Neuroactive ligand-receptor interaction+++04214///Apoptosis - fly+++04979///Cholesterol metabolism+++05166///Human T-cell leukemia virus 1 infection GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005497///androgen binding+++GO:0008503///benzodiazepine receptor activity+++GO:0015485///cholesterol binding+++GO:0044325///ion channel binding GO:0006694///steroid biosynthetic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006869///lipid transport+++GO:0007568///aging+++GO:0008347///glial cell migration+++GO:0010042///response to manganese ion+++GO:0010266///response to vitamin B1+++GO:0010823///negative regulation of mitochondrion organization+++GO:0010940///positive regulation of necrotic cell death+++GO:0014012///peripheral nervous system axon regeneration+++GO:0030325///adrenal gland development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032570///response to progesterone+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033574///response to testosterone+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0048678///response to axon injury+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0051928///positive regulation of calcium ion transport+++GO:0060242///contact inhibition+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060253///negative regulation of glial cell proliferation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071294///cellular response to zinc ion+++GO:0071476///cellular hypotonic response+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0072656///maintenance of protein location in mitochondrion+++GO:1903147///negative regulation of autophagy of mitochondrion+++GO:1903579///negative regulation of ATP metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process 12258 12258 'Serping1' mRNA 3068 3216 3167 96.96 100.17 106.07 326.74 329.8 322.06 101.0666667 326.2 11886 11708 11339 3150.333333 11644.33333 2.61E-236 1.873366126 04610///Complement and coagulation cascades+++05133///Pertussis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0001848///complement binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity "GO:0001869///negative regulation of complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030193///regulation of blood coagulation+++GO:0042730///fibrinolysis+++GO:0045087///innate immune response+++GO:0045916///negative regulation of complement activation" 12259 12259 'C1qa' mRNA 1666 1788 1687 96.64 102.51 103.83 1019.04 1021.01 1026.33 100.9933333 1022.126667 20150 19683 19617 1713.666667 19816.66667 0 3.519847478 04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05020///Prion disease+++05133///Pertussis+++05142///Chagas disease+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0005515///protein binding "GO:0001774///microglial cell activation+++GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0007568///aging+++GO:0010039///response to iron ion+++GO:0016322///neuron remodeling+++GO:0045087///innate immune response+++GO:0048143///astrocyte activation+++GO:0050808///synapse organization+++GO:0098883///synapse pruning+++GO:0150062///complement-mediated synapse pruning+++GO:0150064///vertebrate eye-specific patterning+++GO:1901216///positive regulation of neuron death" 12260 12260 'C1qb' mRNA 1885 2022 1863 106.69 113.09 111.88 1119.14 1205.92 1153.2 110.5533333 1159.42 22682 23830 22594 1923.333333 23035.33333 0 3.571604636 04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05020///Prion disease+++05133///Pertussis+++05142///Chagas disease+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005602///complement component C1 complex+++GO:0005615///extracellular space+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0042802///identical protein binding "GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0048839///inner ear development+++GO:0098883///synapse pruning" 12261 12261 'C1qbp' mRNA 1123 1193 1174 59.56 62.49 66.06 68.31 71.75 76.24 62.70333333 72.1 1478 1514 1595 1163.333333 1529 1.03E-05 0.382198913 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0048786///presynaptic active zone+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0001849///complement component C1q binding+++GO:0003714///transcription corepressor activity+++GO:0003729///mRNA binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005540///hyaluronic acid binding+++GO:0008134///transcription factor binding+++GO:0008494///translation activator activity+++GO:0030984///kininogen binding+++GO:0031690///adrenergic receptor binding+++GO:0097177///mitochondrial ribosome binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0006958///complement activation, classical pathway+++GO:0008380///RNA splicing+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0030449///regulation of complement activation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045785///positive regulation of cell adhesion+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0050687///negative regulation of defense response to virus+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070131///positive regulation of mitochondrial translation+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901165///positive regulation of trophoblast cell migration+++GO:2000510///positive regulation of dendritic cell chemotaxis" 12262 12262 'C1qc' mRNA 1490 1569 1286 88.98 92.54 81.42 655.6 983.64 871.29 87.64666667 836.8433333 12596 18414 16174 1448.333333 15728 1.73E-82 3.436773368 04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05020///Prion disease+++05133///Pertussis+++05142///Chagas disease+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0045202///synapse+++GO:0098794///postsynapse "GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0045087///innate immune response+++GO:0045650///negative regulation of macrophage differentiation+++GO:0098883///synapse pruning" 12263 12263 'C2' mRNA 788 787 733 16.53 16.25 16.31 19.51 19.25 19.19 16.36333333 19.31666667 1070 1031 1019 769.3333333 1040 2.26E-06 0.423783032 04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0007584///response to nutrient+++GO:0045087///innate immune response+++GO:2000427///positive regulation of apoptotic cell clearance" 12265 12265 'Ciita' mRNA 95.34 102.58 125.57 0.73 0.92 1.19 1.36 1.22 1.09 0.946666667 1.223333333 177.78 149.56 137.93 107.83 155.09 0.041602969 0.505088167 04612///Antigen processing and presentation+++05145///Toxoplasmosis+++05152///Tuberculosis+++05164///Influenza A+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016605///PML body "GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0033613///activating transcription factor binding+++GO:0044877///protein-containing complex binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007568///aging+++GO:0016310///phosphorylation+++GO:0034341///response to interferon-gamma+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046597///negative regulation of viral entry into host cell+++GO:0046677///response to antibiotic+++GO:0071257///cellular response to electrical stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071360///cellular response to exogenous dsRNA" 12266 12266 'C3' mRNA 53 77 93 0.77 1.1 1.35 14.62 13.3 14.64 1.073333333 14.18666667 1295 1170 1259 74.33333333 1241.333333 7.53E-160 4.045943621 04080///Neuroactive ligand-receptor interaction+++04145///Phagosome+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04936///Alcoholic liver disease+++05131///Shigellosis+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05142///Chagas disease+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0032991///protein-containing complex GO:0004866///endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0031715///C5L2 anaphylatoxin chemotactic receptor binding "GO:0001798///positive regulation of type IIa hypersensitivity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001970///positive regulation of activation of membrane attack complex+++GO:0002376///immune system process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006954///inflammatory response+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0007596///blood coagulation+++GO:0009617///response to bacterium+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0010866///regulation of triglyceride biosynthetic process+++GO:0010884///positive regulation of lipid storage+++GO:0016322///neuron remodeling+++GO:0035846///oviduct epithelium development+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0045087///innate immune response+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048639///positive regulation of developmental growth+++GO:0050766///positive regulation of phagocytosis+++GO:0060041///retina development in camera-type eye+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097242///amyloid-beta clearance+++GO:0097278///complement-dependent cytotoxicity+++GO:0150062///complement-mediated synapse pruning+++GO:0150064///vertebrate eye-specific patterning+++GO:1905114///cell surface receptor signaling pathway involved in cell-cell signaling+++GO:2000427///positive regulation of apoptotic cell clearance" 12267 12267 'C3ar1' mRNA 211 242 248 2.64 2.98 3.29 50.98 50.7 49.23 2.97 50.30333333 4690 4557 4387 233.6666667 4544.666667 0 4.269025336 04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001850///complement component C3a binding+++GO:0004875///complement receptor activity+++GO:0004876///complement component C3a receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0002430///complement receptor mediated signaling pathway+++GO:0002462///tolerance induction to nonself antigen+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008217///regulation of blood pressure+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:2000573///positive regulation of DNA biosynthetic process 12268 12268 'C4b' mRNA 2362 2423 2518 23.32 23.53 26.38 68.68 66.61 67.24 24.41 67.51 8007 7587 7593 2434.333333 7729 9.38E-147 1.652630323 04610///Complement and coagulation cascades+++04936///Alcoholic liver disease+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0044216///other organism cell+++GO:0045202///synapse+++GO:0106139///symbiont cell surface GO:0001848///complement binding+++GO:0001849///complement component C1q binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0030246///carbohydrate binding "GO:0006954///inflammatory response+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0016064///immunoglobulin mediated immune response+++GO:0045087///innate immune response" 12269 12269 'C4bp' mRNA 0 0 1 0 0 0.04 0.09 0.19 0.12 0.013333333 0.133333333 3 7 4 0.333333333 4.666666667 0.068155185 3.698670327 04610///Complement and coagulation cascades+++05133///Pertussis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding "GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0009609///response to symbiotic bacterium+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:1903027///regulation of opsonization" 12273 12273 'C5ar1' mRNA 171 177 211 3.8 3.92 5.01 66.51 64.9 64.43 4.243333333 65.28 3416 3261 3208 186.3333333 3295 0 4.130145425 04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04936///Alcoholic liver disease+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045177///apical part of cell GO:0001856///complement component C5a binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004875///complement receptor activity+++GO:0004878///complement component C5a receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0030414///peptidase inhibitor activity GO:0001774///microglial cell activation+++GO:0002430///complement receptor mediated signaling pathway+++GO:0006915///apoptotic process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010951///negative regulation of endopeptidase activity+++GO:0021534///cell proliferation in hindbrain+++GO:0030593///neutrophil chemotaxis+++GO:0032494///response to peptidoglycan+++GO:0038178///complement component C5a signaling pathway+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043086///negative regulation of catalytic activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0048143///astrocyte activation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050890///cognition+++GO:0052547///regulation of peptidase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0097242///amyloid-beta clearance+++GO:0099172///presynapse organization+++GO:1902947///regulation of tau-protein kinase activity 12274 12274 'C6' mRNA 42 43 46 0.82 0.81 0.95 0.52 0.65 0.81 0.86 0.66 26 38 41 43.66666667 35 0.497098225 -0.330028985 04610///Complement and coagulation cascades+++05020///Prion disease+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005615///extracellular space "GO:0001701///in utero embryonic development+++GO:0001970///positive regulation of activation of membrane attack complex+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0006958///complement activation, classical pathway+++GO:0019835///cytolysis+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0045917///positive regulation of complement activation" 12279 12279 'C9' mRNA 7 14 10 0.19 0.37 0.29 0.26 0.38 0.56 0.283333333 0.4 11 16 23 10.33333333 16.66666667 0.399893123 0.683793038 04610///Complement and coagulation cascades+++05020///Prion disease+++05146///Amoebiasis+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044218///other organism cell membrane "GO:0001906///cell killing+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0007596///blood coagulation+++GO:0019835///cytolysis+++GO:0045087///innate immune response+++GO:0051260///protein homooligomerization" 12282 12282 'Hyou1' mRNA 1227 1299 1026 14.64 15.25 12.98 18.51 15.87 17.5 14.29 17.29333333 1784 1496 1636 1184 1638.666667 2.51E-07 0.459679315 04141///Protein processing in endoplasmic reticulum GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0034663///endoplasmic reticulum chaperone complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0001666///response to hypoxia+++GO:0002931///response to ischemia+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043066///negative regulation of apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway 12283 12283 'Cab39' mRNA 645.36 626.4 638.75 9.19 8.71 9.72 12.45 10.99 12.21 9.206666667 11.88333333 975.52 842.42 926.6 636.8366667 914.8466667 5.22E-07 0.509335226 04150///mTOR signaling pathway+++04152///AMPK signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0032991///protein-containing complex GO:0005509///calcium ion binding+++GO:0019900///kinase binding+++GO:0030295///protein kinase activator activity+++GO:0043539///protein serine/threonine kinase activator activity GO:0007165///signal transduction+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0014823///response to activity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0097066///response to thyroid hormone 12286 12286 'Cacna1a' mRNA 33 43 26 0.21 0.27 0.17 0.16 0.27 0.25 0.216666667 0.226666667 29 45 44 34 39.33333333 0.712413939 0.209571875 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04930///Type II diabetes mellitus+++05017///Spinocerebellar ataxia+++05032///Morphine addiction+++05033///Nicotine addiction+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019905///syntaxin binding+++GO:0046872///metal ion binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels "GO:0001505///regulation of neurotransmitter levels+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0007416///synapse assembly+++GO:0007628///adult walking behavior+++GO:0008219///cell death+++GO:0010817///regulation of hormone levels+++GO:0014051///gamma-aminobutyric acid secretion+++GO:0014056///regulation of acetylcholine secretion, neurotransmission+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0019226///transmission of nerve impulse+++GO:0019233///sensory perception of pain+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021590///cerebellum maturation+++GO:0021679///cerebellar molecular layer development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021750///vestibular nucleus development+++GO:0021953///central nervous system neuron differentiation+++GO:0030644///cellular chloride ion homeostasis+++GO:0031335///regulation of sulfur amino acid metabolic process+++GO:0032353///negative regulation of hormone biosynthetic process+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0042593///glucose homeostasis+++GO:0043113///receptor clustering+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0048813///dendrite morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050877///nervous system process+++GO:0050883///musculoskeletal movement, spinal reflex action+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process+++GO:0051899///membrane depolarization+++GO:0051932///synaptic transmission, GABAergic+++GO:0055085///transmembrane transport+++GO:0060024///rhythmic synaptic transmission+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1904645///response to amyloid-beta+++GO:1904646///cellular response to amyloid-beta" 12287 12287 'Cacna1b' mRNA 29 18 20 0.22 0.12 0.16 0.07 0.02 0.08 0.166666667 0.056666667 11 3 11 22.33333333 8.333333333 0.046454425 -1.438155749 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04930///Type II diabetes mellitus+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05032///Morphine addiction+++05033///Nicotine addiction+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043679///axon terminus+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0046872///metal ion binding+++GO:0051721///protein phosphatase 2A binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007626///locomotory behavior+++GO:0008016///regulation of heart contraction+++GO:0008217///regulation of blood pressure+++GO:0014070///response to organic cyclic compound+++GO:0019233///sensory perception of pain+++GO:0033574///response to testosterone+++GO:0034765///regulation of ion transmembrane transport+++GO:0048265///response to pain+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051924///regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:1904645///response to amyloid-beta 12288 12288 'Cacna1c' mRNA 107 119 102 0.46 0.48 0.5 0.23 0.25 0.14 0.48 0.206666667 66 63 38 109.3333333 55.66666667 9.66E-04 -0.98490824 "04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04742///Taste transduction+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05207///Chemical carcinogenesis - receptor activation+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy" GO:0002095///caveolar macromolecular signaling complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031369///translation initiation factor binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051393///alpha-actinin binding+++GO:0051721///protein phosphatase 2A binding+++GO:0086007///voltage-gated calcium channel activity involved in cardiac muscle cell action potential+++GO:0086056///voltage-gated calcium channel activity involved in AV node cell action potential+++GO:1905030///voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0002520///immune system development+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006939///smooth muscle contraction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007507///heart development+++GO:0007628///adult walking behavior+++GO:0008217///regulation of blood pressure+++GO:0008542///visual learning+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0017156///calcium ion regulated exocytosis+++GO:0019229///regulation of vasoconstriction+++GO:0030073///insulin secretion+++GO:0030252///growth hormone secretion+++GO:0034765///regulation of ion transmembrane transport+++GO:0035115///embryonic forelimb morphogenesis+++GO:0042593///glucose homeostasis+++GO:0043010///camera-type eye development+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0046620///regulation of organ growth+++GO:0055085///transmembrane transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0060402///calcium ion transport into cytosol+++GO:0061337///cardiac conduction+++GO:0061577///calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086045///membrane depolarization during AV node cell action potential+++GO:0086065///cell communication involved in cardiac conduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098703///calcium ion import across plasma membrane+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:0098912///membrane depolarization during atrial cardiac muscle cell action potential+++GO:1904879///positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 12289 12289 'Cacna1d' mRNA 1204.66 1329.37 1177.16 6.89 7.59 7.19 3.42 2.82 3.23 7.223333333 3.156666667 660.17 552.28 607.98 1237.063333 606.81 2.04E-28 -1.040097986 "04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04218///Cellular senescence+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04530///Tight junction+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05207///Chemical carcinogenesis - receptor activation+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0042383///sarcolemma+++GO:0043025///neuronal cell body+++GO:0098683///cochlear hair cell ribbon synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0030165///PDZ domain binding+++GO:0030506///ankyrin binding+++GO:0046872///metal ion binding+++GO:0051393///alpha-actinin binding+++GO:0086059///voltage-gated calcium channel activity involved SA node cell action potential+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0019722///calcium-mediated signaling+++GO:0030001///metal ion transport+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0051924///regulation of calcium ion transport+++GO:0051928///positive regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0061337///cardiac conduction+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1904879///positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 12290 12290 'Cacna1e' mRNA 2294.74 2277.68 1998 7.04 7.28 7.19 3.49 3.45 3.38 7.17 3.44 1238.98 1130.95 1188.82 2190.14 1186.25 2.37E-35 -0.895530535 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04930///Type II diabetes mellitus GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043204///perikaryon+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0022843///voltage-gated cation channel activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels GO:0001662///behavioral fear response+++GO:0002027///regulation of heart rate+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0019226///transmission of nerve impulse+++GO:0019233///sensory perception of pain+++GO:0030317///flagellated sperm motility+++GO:0034765///regulation of ion transmembrane transport+++GO:0042593///glucose homeostasis+++GO:0042596///fear response+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0050877///nervous system process+++GO:0055085///transmembrane transport+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0090273///regulation of somatostatin secretion+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration 12291 12291 'Cacna1g' mRNA 70 64 73 0.47 0.45 0.5 0.06 0.13 0.09 0.473333333 0.093333333 10 21 16 69 15.66666667 2.82E-07 -2.14970099 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04713///Circadian entrainment+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04934///Cushing syndrome GO:0001518///voltage-gated sodium channel complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008332///low voltage-gated calcium channel activity+++GO:0086056///voltage-gated calcium channel activity involved in AV node cell action potential+++GO:0086059///voltage-gated calcium channel activity involved SA node cell action potential+++GO:0097110///scaffold protein binding GO:0001508///action potential+++GO:0002027///regulation of heart rate+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0010045///response to nickel cation+++GO:0014824///artery smooth muscle contraction+++GO:0019228///neuronal action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0051924///regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0060402///calcium ion transport into cytosol+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086010///membrane depolarization during action potential+++GO:0086015///SA node cell action potential+++GO:0086016///AV node cell action potential+++GO:0086018///SA node cell to atrial cardiac muscle cell signaling+++GO:0086027///AV node cell to bundle of His cell signaling+++GO:0086045///membrane depolarization during AV node cell action potential+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction 12292 12292 'Cacna1s' mRNA 1 2 1 0.01 0.02 0.01 0 0.01 0.02 0.013333333 0.01 0 1 2 1.333333333 1 0.88564318 -0.407849498 "04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04723///Retrograde endocannabinoid signaling+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05207///Chemical carcinogenesis - receptor activation+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0031674///I band+++GO:0042383///sarcolemma+++GO:0044327///dendritic spine head+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005516///calmodulin binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0002074///extraocular skeletal muscle development+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006936///muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007029///endoplasmic reticulum organization+++GO:0007519///skeletal muscle tissue development+++GO:0007520///myoblast fusion+++GO:0007528///neuromuscular junction development+++GO:0034765///regulation of ion transmembrane transport+++GO:0043501///skeletal muscle adaptation+++GO:0048741///skeletal muscle fiber development+++GO:0055001///muscle cell development+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0071313///cellular response to caffeine 12293 12293 'Cacna2d1' mRNA 9080.89 9156.03 8739.42 39.35 38.89 39.9 26.61 24.45 25.41 39.38 25.49 7289.34 6541.69 6752.27 8992.113333 6861.1 4.57E-14 -0.402800313 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0098978///glutamatergic synapse+++GO:0099025///anchored component of postsynaptic membrane+++GO:0099029///anchored component of presynaptic active zone membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0086057///voltage-gated calcium channel activity involved in bundle of His cell action potential GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051924///regulation of calcium ion transport+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060402///calcium ion transport into cytosol+++GO:0061577///calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0070588///calcium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086048///membrane depolarization during bundle of His cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098903///regulation of membrane repolarization during action potential+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1901843///positive regulation of high voltage-gated calcium channel activity+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:1904646///cellular response to amyloid-beta 12294 12294 'Cacna2d3' mRNA 78 68 69 1.11 0.95 1.06 0.11 0.2 0.15 1.04 0.153333333 8 16 12 71.66666667 12 1.56E-09 -2.586738346 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport 12295 12295 'Cacnb1' mRNA 248.66 268.88 180.97 4.51 4.84 3.64 2.95 3.51 2.35 4.33 2.936666667 155.55 187.48 128.21 232.8366667 157.08 0.00852967 -0.569755657 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0042383///sarcolemma+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding GO:0006612///protein targeting to membrane+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0034765///regulation of ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:1904646///cellular response to amyloid-beta 12296 12296 'Cacnb2' mRNA 172 153 132 1.76 1.51 1.42 1.14 0.83 0.86 1.563333333 0.943333333 129 92 92 152.3333333 104.3333333 0.022222464 -0.557362558 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0098684///photoreceptor ribbon synapse+++GO:0098793///presynapse+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding+++GO:0051219///phosphoprotein binding+++GO:0086007///voltage-gated calcium channel activity involved in cardiac muscle cell action potential+++GO:0086056///voltage-gated calcium channel activity involved in AV node cell action potential+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0007601///visual perception+++GO:0034765///regulation of ion transmembrane transport+++GO:0051928///positive regulation of calcium ion transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0086045///membrane depolarization during AV node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098912///membrane depolarization during atrial cardiac muscle cell action potential+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901843///positive regulation of high voltage-gated calcium channel activity+++GO:1904879///positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 12297 12297 'Cacnb3' mRNA 529 537 416 11.38 11.04 9.54 8.51 8.96 8.36 10.65333333 8.61 449 458 425 494 444 0.266137772 -0.161000914 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0045202///synapse+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019901///protein kinase binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0034765///regulation of ion transmembrane transport+++GO:0050852///T cell receptor signaling pathway+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0060402///calcium ion transport into cytosol+++GO:0061577///calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0070588///calcium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0098903///regulation of membrane repolarization during action potential+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1901843///positive regulation of high voltage-gated calcium channel activity+++GO:1902630///regulation of membrane hyperpolarization+++GO:1905788///negative regulation of detection of mechanical stimulus involved in sensory perception of touch+++GO:2000463///positive regulation of excitatory postsynaptic potential 12298 12298 'Cacnb4' mRNA 217 249 250 1.84 1.97 2.39 0.7 0.87 1.1 2.066666667 0.89 107 118 138 238.6666667 121 6.09E-07 -0.992567634 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016607///nuclear speck+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008331///high voltage-gated calcium channel activity+++GO:0019901///protein kinase binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels "GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0007628///adult walking behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0014051///gamma-aminobutyric acid secretion+++GO:0019227///neuronal action potential propagation+++GO:0030217///T cell differentiation+++GO:0034765///regulation of ion transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0046058///cAMP metabolic process+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048541///Peyer's patch development+++GO:0048747///muscle fiber development+++GO:0050852///T cell receptor signaling pathway+++GO:0050877///nervous system process+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0051932///synaptic transmission, GABAergic+++GO:0055001///muscle cell development+++GO:0070588///calcium ion transmembrane transport+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000300///regulation of synaptic vesicle exocytosis" 12299 12299 'Cacng1' mRNA 0 0 2 0 0 0.11 0.13 0.14 0.18 0.036666667 0.15 3 3 4 0.666666667 3.333333333 0.307903837 2.269978093 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0042383///sarcolemma+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 12300 12300 'Cacng2' mRNA 1 1 0 0.01 0.01 0 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0036477///somatodendritic compartment+++GO:0043005///neuron projection+++GO:0044300///cerebellar mossy fiber+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0016247///channel regulator activity+++GO:0035255///ionotropic glutamate receptor binding "GO:0006612///protein targeting to membrane+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007528///neuromuscular junction development+++GO:0019226///transmission of nerve impulse+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051592///response to calcium ion+++GO:0051899///membrane depolarization+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060081///membrane hyperpolarization+++GO:0060082///eye blink reflex+++GO:0070588///calcium ion transmembrane transport+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0099590///neurotransmitter receptor internalization+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1904510///positive regulation of protein localization to basolateral plasma membrane+++GO:2000311///regulation of AMPA receptor activity+++GO:2000969///positive regulation of AMPA receptor activity" 12301 12301 'Cacybp' mRNA 2552.91 2468.96 2389.94 68.32 65.08 67.85 52.69 53.78 55.78 67.08333333 54.08333333 2263.95 2256.03 2320 2470.603333 2279.993333 0.083094099 -0.126847663 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030877///beta-catenin destruction complex+++GO:0043005///neuron projection+++GO:0044297///cell body GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding GO:0007507///heart development+++GO:0007568///aging+++GO:0045740///positive regulation of DNA replication+++GO:0055007///cardiac muscle cell differentiation+++GO:0060416///response to growth hormone+++GO:0060548///negative regulation of cell death+++GO:0071277///cellular response to calcium ion+++GO:1990830///cellular response to leukemia inhibitory factor 12304 12304 'Pdia4' mRNA 7803 7881 7542 175.31 174.33 179.75 197.1 187.22 186.77 176.4633333 190.3633333 10091 9360 9258 7742 9569.666667 2.93E-08 0.293376692 04141///Protein processing in endoplasmic reticulum+++04918///Thyroid hormone synthesis+++05110///Vibrio cholerae infection GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0009986///cell surface+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0042470///melanosome GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity GO:0006457///protein folding+++GO:0034976///response to endoplasmic reticulum stress+++GO:0061077///chaperone-mediated protein folding+++GO:1903334///positive regulation of protein folding 12305 12305 'Ddr1' mRNA 3250.32 3539.01 2516.11 42.34 45.6 34.27 45.63 50.09 46.8 40.73666667 47.50666667 3955.96 4270.41 3939.81 3101.813333 4055.393333 1.66E-05 0.382210992 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005518///collagen binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0038062///protein tyrosine kinase collagen receptor activity+++GO:0046872///metal ion binding "GO:0001558///regulation of cell growth+++GO:0001952///regulation of cell-matrix adhesion+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007565///female pregnancy+++GO:0007566///embryo implantation+++GO:0007595///lactation+++GO:0008285///negative regulation of cell proliferation+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0014909///smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0043583///ear development+++GO:0044319///wound healing, spreading of cells+++GO:0046777///protein autophosphorylation+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060749///mammary gland alveolus development+++GO:0061302///smooth muscle cell-matrix adhesion+++GO:0061564///axon development+++GO:1990138///neuron projection extension" 12306 12306 'Anxa2' mRNA 7972 8279 7856 342.61 351.66 358.79 580.65 591.63 573.15 351.02 581.81 15372 15270 14677 8035.666667 15106.33333 1.16E-70 0.898930036 05132///Salmonella infection GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0035749///myelin sheath adaxonal region+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0043220///Schmidt-Lanterman incisure+++GO:0044354///macropinosome+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:1990665///AnxA2-p11 complex+++GO:1990667///PCSK9-AnxA2 complex "GO:0001786///phosphatidylserine binding+++GO:0002020///protease binding+++GO:0004859///phospholipase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008092///cytoskeletal protein binding+++GO:0019834///phospholipase A2 inhibitor activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0044548///S100 protein binding+++GO:0044730///bone sialoprotein binding+++GO:0046790///virion binding+++GO:0048306///calcium-dependent protein binding" GO:0001525///angiogenesis+++GO:0001765///membrane raft assembly+++GO:0001921///positive regulation of receptor recycling+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006900///vesicle budding from membrane+++GO:0007589///body fluid secretion+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030199///collagen fibril organization+++GO:0031340///positive regulation of vesicle fusion+++GO:0032804///negative regulation of low-density lipoprotein particle receptor catabolic process+++GO:0036035///osteoclast development+++GO:0042730///fibrinolysis+++GO:0043086///negative regulation of catalytic activity+++GO:0044090///positive regulation of vacuole organization+++GO:0044147///negative regulation of development of symbiont involved in interaction with host+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051099///positive regulation of binding+++GO:0052362///catabolism by host of symbiont protein+++GO:0052405///negative regulation by host of symbiont molecular function+++GO:0070588///calcium ion transmembrane transport+++GO:0071229///cellular response to acid chemical+++GO:0072659///protein localization to plasma membrane+++GO:0097066///response to thyroid hormone+++GO:1905581///positive regulation of low-density lipoprotein particle clearance+++GO:1905597///positive regulation of low-density lipoprotein particle receptor binding+++GO:1905599///positive regulation of low-density lipoprotein receptor activity+++GO:1905602///positive regulation of receptor-mediated endocytosis involved in cholesterol transport 12307 12307 'Calb1' mRNA 112 91 88 2.15 1.72 1.79 0.13 0.17 0.21 1.886666667 0.17 8 10 12 97 10 5.59E-16 -3.287009037 04961///Endocrine and other factor-regulated calcium reabsorption GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044297///cell body+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0005499///vitamin D binding+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0099534///calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration+++GO:0099567///calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration GO:0007611///learning or memory+++GO:0007614///short-term memory+++GO:0007616///long-term memory+++GO:0007626///locomotory behavior+++GO:0010842///retina layer formation+++GO:0035502///metanephric part of ureteric bud development+++GO:0048167///regulation of synaptic plasticity+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055074///calcium ion homeostasis+++GO:0060041///retina development in camera-type eye+++GO:0071310///cellular response to organic substance+++GO:0072205///metanephric collecting duct development+++GO:0072221///metanephric distal convoluted tubule development+++GO:0072286///metanephric connecting tubule development+++GO:0090102///cochlea development+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1900271///regulation of long-term synaptic potentiation 12308 12308 'Calb2' mRNA 2642 2667 2278 108.32 107.91 99.09 14.35 17.05 16.24 105.1066667 15.88 402 466 440 2529 436 4.86E-185 -2.544076054 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005921///gap junction+++GO:0030425///dendrite+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0099534///calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1900271///regulation of long-term synaptic potentiation 12309 12309 'S100g' mRNA 1 0 0 0.18 0 0 0.32 0.99 0.17 0.06 0.493333333 2 6 1 0.333333333 3 0.208716763 3.063691575 04978///Mineral absorption GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0005499///vitamin D binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding+++GO:0048306///calcium-dependent protein binding 12310 12310 'Calca' mRNA 310 284 293 21 19.9 22.02 35.63 44.9 39.61 20.97333333 40.04666667 564 688 602 295.6666667 618 3.79E-15 1.053202272 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0031716///calcitonin receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding "GO:0001935///endothelial cell proliferation+++GO:0001944///vasculature development+++GO:0001976///neurological system process involved in regulation of systemic arterial blood pressure+++GO:0001984///artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure+++GO:0002027///regulation of heart rate+++GO:0002031///G protein-coupled receptor internalization+++GO:0002548///monocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0006954///inflammatory response+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0007528///neuromuscular junction development+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0007631///feeding behavior+++GO:0008016///regulation of heart contraction+++GO:0008217///regulation of blood pressure+++GO:0009408///response to heat+++GO:0010523///negative regulation of calcium ion transport into cytosol+++GO:0030279///negative regulation of ossification+++GO:0031623///receptor internalization+++GO:0031645///negative regulation of neurological system process+++GO:0032147///activation of protein kinase activity+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0042311///vasodilation+++GO:0043542///endothelial cell migration+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045776///negative regulation of blood pressure+++GO:0045778///positive regulation of ossification+++GO:0045779///negative regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0048240///sperm capacitation+++GO:0048265///response to pain+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0071356///cellular response to tumor necrosis factor+++GO:0097647///amylin receptor signaling pathway+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway" 12311 12311 'Calcr' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction+++04380///Osteoclast differentiation GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0150056///amylin receptor complex 1+++GO:0150057///amylin receptor complex 2+++GO:0150058///amylin receptor complex 3 GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004948///calcitonin receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0032841///calcitonin binding+++GO:0097643///amylin receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010628///positive regulation of gene expression+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0010942///positive regulation of cell death+++GO:0030279///negative regulation of ossification+++GO:0030316///osteoclast differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038041///cross-receptor inhibition within G protein-coupled receptor heterodimer+++GO:0043488///regulation of mRNA stability+++GO:0045124///regulation of bone resorption+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0051384///response to glucocorticoid+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097647///amylin receptor signaling pathway+++GO:1904645///response to amyloid-beta+++GO:1905665///positive regulation of calcium ion import across plasma membrane 12313 12313 'Calm1' mRNA 22588 22645 23804 295.13 291 329.91 209.67 223.45 210.48 305.3466667 214.5333333 18472 19231 17959 23012.33333 18554 6.32E-07 -0.324427328 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04744///Phototransduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04970///Salivary secretion+++04971///Gastric acid secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05034///Alcoholism+++05133///Pertussis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05214///Glioma+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0030017///sarcomere+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0034704///calcium channel complex+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:1902494///catalytic complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0010856///adenylate cyclase activator activity+++GO:0019855///calcium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030234///enzyme regulator activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0031432///titin binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0031997///N-terminal myristoylation domain binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0072542///protein phosphatase activator activity+++GO:0097718///disordered domain specific binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001975///response to amphetamine+++GO:0002027///regulation of heart rate+++GO:0005513///detection of calcium ion+++GO:0007190///activation of adenylate cyclase activity+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0016240///autophagosome membrane docking+++GO:0019722///calcium-mediated signaling+++GO:0031279///regulation of cyclase activity+++GO:0032465///regulation of cytokinesis+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051412///response to corticosterone+++GO:0051592///response to calcium ion+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0090150///establishment of protein localization to membrane+++GO:0090151///establishment of protein localization to mitochondrial membrane+++GO:0098901///regulation of cardiac muscle cell action potential+++GO:0140056///organelle localization by membrane tethering+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering+++GO:2000300///regulation of synaptic vesicle exocytosis 12314 12314 'Calm2' mRNA 38548 39628 38665 1942.52 1971.98 2067.07 731.52 743.01 739.8 1993.856667 738.11 16661 16504 16291 38947 16485.33333 1.31E-142 -1.252746531 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04744///Phototransduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04970///Salivary secretion+++04971///Gastric acid secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05034///Alcoholism+++05133///Pertussis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05214///Glioma+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031966///mitochondrial membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0034704///calcium channel complex+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:1902494///catalytic complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0010856///adenylate cyclase activator activity+++GO:0019855///calcium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030234///enzyme regulator activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0031432///titin binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0031997///N-terminal myristoylation domain binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0072542///protein phosphatase activator activity+++GO:0097718///disordered domain specific binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001975///response to amphetamine+++GO:0002027///regulation of heart rate+++GO:0005513///detection of calcium ion+++GO:0007190///activation of adenylate cyclase activity+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0016240///autophagosome membrane docking+++GO:0019722///calcium-mediated signaling+++GO:0031279///regulation of cyclase activity+++GO:0032465///regulation of cytokinesis+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051412///response to corticosterone+++GO:0051592///response to calcium ion+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0090150///establishment of protein localization to membrane+++GO:0090151///establishment of protein localization to mitochondrial membrane+++GO:0098901///regulation of cardiac muscle cell action potential+++GO:0140056///organelle localization by membrane tethering+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1901020///negative regulation of calcium ion transmembrane transporter activity+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:1905913///negative regulation of calcium ion export across plasma membrane+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering+++GO:2000300///regulation of synaptic vesicle exocytosis 12315 12315 'Calm3' mRNA 1944 2080 1460 49.62 52.28 39.53 47.03 50.26 46.98 47.14333333 48.09 2119 2211 2049 1828 2126.333333 0.036251432 0.213631422 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04744///Phototransduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04970///Salivary secretion+++04971///Gastric acid secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05034///Alcoholism+++05133///Pertussis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05214///Glioma+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0030017///sarcomere+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0034704///calcium channel complex+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:1902494///catalytic complex GO:0005509///calcium ion binding+++GO:0008179///adenylate cyclase binding+++GO:0010856///adenylate cyclase activator activity+++GO:0019855///calcium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030234///enzyme regulator activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0031432///titin binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0031997///N-terminal myristoylation domain binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0072542///protein phosphatase activator activity+++GO:0097718///disordered domain specific binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001975///response to amphetamine+++GO:0002027///regulation of heart rate+++GO:0005513///detection of calcium ion+++GO:0007190///activation of adenylate cyclase activity+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0016240///autophagosome membrane docking+++GO:0019722///calcium-mediated signaling+++GO:0031279///regulation of cyclase activity+++GO:0032465///regulation of cytokinesis+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051412///response to corticosterone+++GO:0051592///response to calcium ion+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0090150///establishment of protein localization to membrane+++GO:0090151///establishment of protein localization to mitochondrial membrane+++GO:0098901///regulation of cardiac muscle cell action potential+++GO:0140056///organelle localization by membrane tethering+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering+++GO:2000300///regulation of synaptic vesicle exocytosis 12316 12316 'Aspm' mRNA 10.03 6.81 3.01 0.1 0.06 0.03 1.04 0.9 0.83 0.063333333 0.923333333 196.82 160.01 154.43 6.616666667 170.42 9.74E-30 4.737129067 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016324///apical plasma membrane+++GO:0030496///midbody+++GO:0036449///microtubule minus-end+++GO:0072687///meiotic spindle+++GO:0097431///mitotic spindle pole GO:0005516///calmodulin binding GO:0001764///neuron migration+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0008584///male gonad development+++GO:0021873///forebrain neuroblast division+++GO:0021987///cerebral cortex development+++GO:0045665///negative regulation of neuron differentiation+++GO:0045769///negative regulation of asymmetric cell division+++GO:0048477///oogenesis+++GO:0048589///developmental growth+++GO:0051301///cell division+++GO:0051445///regulation of meiotic cell cycle+++GO:0051653///spindle localization+++GO:0051661///maintenance of centrosome location+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090306///spindle assembly involved in meiosis+++GO:0097150///neuronal stem cell population maintenance 12317 12317 'Calr' mRNA 9979 10427 9751 293.35 302.01 304.09 415.59 411.84 408.08 299.8166667 411.8366667 16252 15722 15445 10052.33333 15806.33333 1.54E-40 0.641300474 04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++04612///Antigen processing and presentation+++05142///Chagas disease+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0042824///MHC class I peptide loading complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0060473///cortical granule+++GO:0062023///collagen-containing extracellular matrix GO:0003729///mRNA binding+++GO:0005178///integrin binding+++GO:0005506///iron ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042277///peptide binding+++GO:0042562///hormone binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051082///unfolded protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002502///peptide antigen assembly with MHC class I protein complex+++GO:0006457///protein folding+++GO:0006611///protein export from nucleus+++GO:0007283///spermatogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032355///response to estradiol+++GO:0033144///negative regulation of intracellular steroid hormone receptor signaling pathway+++GO:0033574///response to testosterone+++GO:0034504///protein localization to nucleus+++GO:0040020///regulation of meiotic nuclear division+++GO:0042493///response to drug+++GO:0045665///negative regulation of neuron differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0050766///positive regulation of phagocytosis+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:0055007///cardiac muscle cell differentiation+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071285///cellular response to lithium ion+++GO:0071310///cellular response to organic substance+++GO:0090398///cellular senescence+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901164///negative regulation of trophoblast cell migration+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000510///positive regulation of dendritic cell chemotaxis" 12319 12319 'Car8' mRNA 69 72 74 0.64 0.66 0.73 0.73 0.58 0.61 0.676666667 0.64 91 70 73 71.66666667 78 0.785321448 0.106867612 00910///Nitrogen metabolism GO:0005737///cytoplasm GO:0004089///carbonate dehydratase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling 12321 12321 'Calu' mRNA 6479 6542 6603 109.69 108.97 118.56 160.49 143.42 144.8 112.4066667 149.57 10909 9502 9531 6541.333333 9980.666667 5.13E-21 0.595089853 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle GO:0004857///enzyme inhibitor activity+++GO:0005509///calcium ion binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0043086///negative regulation of catalytic activity 12322 12322 'Camk2a' mRNA 16 22 7 0.26 0.33 0.09 0.17 0.33 0.45 0.226666667 0.316666667 15 29 37 15 27 0.203263435 0.858480319 04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04114///Oocyte meiosis+++04217///Necroptosis+++04261///Adrenergic signaling in cardiomyocytes+++04310///Wnt signaling pathway+++04360///Axon guidance+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04934///Cushing syndrome+++04971///Gastric acid secretion+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005954///calcium- and calmodulin-dependent protein kinase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol+++GO:0099573///glutamatergic postsynaptic density+++GO:0099634///postsynaptic specialization membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0032794///GTPase activating protein binding+++GO:0035254///glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0038166///angiotensin-activated signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048813///dendrite morphogenesis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051346///negative regulation of hydrolase activity+++GO:0051928///positive regulation of calcium ion transport+++GO:0060996///dendritic spine development+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0098989///NMDA selective glutamate receptor signaling pathway+++GO:0099004///calmodulin dependent kinase signaling pathway+++GO:0099148///regulation of synaptic vesicle docking+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1990443///peptidyl-threonine autophosphorylation+++GO:2000124///regulation of endocannabinoid signaling pathway+++GO:2001222///regulation of neuron migration 12323 12323 'Camk2b' mRNA 1567 1549 1391 20.63 20.05 19.49 2.68 2.97 2.98 20.05666667 2.876666667 230 256 250 1502.333333 245.3333333 3.66E-149 -2.623738734 04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04114///Oocyte meiosis+++04217///Necroptosis+++04261///Adrenergic signaling in cardiomyocytes+++04310///Wnt signaling pathway+++04360///Axon guidance+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04934///Cushing syndrome+++04971///Gastric acid secretion+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005954///calcium- and calmodulin-dependent protein kinase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0051233///spindle midzone+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043274///phospholipase binding+++GO:0098973///structural constituent of postsynaptic actin cytoskeleton "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0002030///inhibitory G protein-coupled receptor phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0007399///nervous system development+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0032222///regulation of synaptic transmission, cholinergic+++GO:0032430///positive regulation of phospholipase A2 activity+++GO:0046686///response to cadmium ion+++GO:0046777///protein autophosphorylation+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048858///cell projection morphogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0060291///long-term synaptic potentiation+++GO:0060466///activation of meiosis involved in egg activation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0090129///positive regulation of synapse maturation+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1903076///regulation of protein localization to plasma membrane+++GO:2001222///regulation of neuron migration+++GO:2001235///positive regulation of apoptotic signaling pathway" 12325 12325 'Camk2g' mRNA 973 1057 985 14.31 15.22 15.29 11.73 10.81 12.78 14.94 11.77333333 915 831 970 1005 905.3333333 0.123159945 -0.162678784 04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04114///Oocyte meiosis+++04217///Necroptosis+++04261///Adrenergic signaling in cardiomyocytes+++04310///Wnt signaling pathway+++04360///Axon guidance+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04934///Cushing syndrome+++04971///Gastric acid secretion+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005954///calcium- and calmodulin-dependent protein kinase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0043005///neuron projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001666///response to hypoxia+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006979///response to oxidative stress+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010975///regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0046777///protein autophosphorylation+++GO:1901897///regulation of relaxation of cardiac muscle+++GO:1903076///regulation of protein localization to plasma membrane 12326 12326 'Camk4' mRNA 128.47 105.58 115.8 0.55 0.44 0.52 0.28 0.29 0.23 0.503333333 0.266666667 75.25 76.4 60.43 116.6166667 70.69333333 0.00671335 -0.73476181 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04211///Longevity regulating pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++05031///Amphetamine addiction+++05034///Alcoholism+++05214///Glioma GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006913///nucleocytoplasmic transport+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007616///long-term memory+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0099527///postsynapse to nucleus signaling pathway" 12328 12328 'Caml' mRNA 881 840 894 38 35.75 40.91 28.21 28.22 27.38 38.22 27.93666667 751 733 705 871.6666667 729.6666667 0.01057722 -0.27021793 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043529///GET complex GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0050839///cell adhesion molecule binding GO:0001782///B cell homeostasis+++GO:0001881///receptor recycling+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0016192///vesicle-mediated transport+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0050821///protein stabilization+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 12330 12330 'Canx' mRNA 12086 11842 11952 151.67 146.13 159.07 184.9 167 179.19 152.29 177.03 16964 14962 15918 11960 15948 2.51E-12 0.401245561 04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++04612///Antigen processing and presentation+++04918///Thyroid hormone synthesis+++05166///Human T-cell leukemia virus 1 infection GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043209///myelin sheath+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0034185///apolipoprotein binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007568///aging+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0048488///synaptic vesicle endocytosis+++GO:0072583///clathrin-dependent endocytosis 12331 12331 'Cap1' mRNA 3554.74 3823.75 2714 70.71 74.93 57.31 98.41 94.3 94.65 67.65 95.78666667 5693.63 5325.22 5300.42 3364.163333 5439.756667 2.38E-17 0.687769823 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding GO:0000902///cell morphogenesis+++GO:0001667///ameboidal-type cell migration+++GO:0006898///receptor-mediated endocytosis+++GO:0007010///cytoskeleton organization+++GO:0019933///cAMP-mediated signaling+++GO:0030036///actin cytoskeleton organization+++GO:0045761///regulation of adenylate cyclase activity 12332 12332 'Capg' mRNA 5720 5874 5680 281.57 285.96 297.11 454.69 460.4 440.44 288.2133333 451.8433333 10798 10694 10120 5758 10537.33333 4.76E-56 0.859711729 GO:0001726///ruffle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0045335///phagocytic vesicle+++GO:0072686///mitotic spindle+++GO:0090543///Flemming body "GO:0003779///actin binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding" GO:0007417///central nervous system development+++GO:0008154///actin polymerization or depolymerization+++GO:0030031///cell projection assembly+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping+++GO:0071346///cellular response to interferon-gamma 12333 12333 'Capn1' mRNA 385 403 349 6.93 7.1 6.59 11.62 12.76 11.59 6.873333333 11.99 748 798 724 379 756.6666667 7.88E-19 0.988224431 04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04217///Necroptosis+++04218///Cellular senescence+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0016540///protein autoprocessing+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032801///receptor catabolic process+++GO:0043117///positive regulation of vascular permeability+++GO:0050790///regulation of catalytic activity+++GO:0060056///mammary gland involution+++GO:0070301///cellular response to hydrogen peroxide+++GO:0097264///self proteolysis+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1990776///response to angiotensin 12334 12334 'Capn2' mRNA 2350 2430 1812 38.64 39.32 31.61 43.48 45.56 44.42 36.52333333 44.48666667 3043 3114 3010 2197.333333 3055.666667 1.20E-08 0.470011181 04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04217///Necroptosis+++04218///Cellular senescence+++04510///Focal adhesion+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031143///pseudopodium+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0097038///perinuclear endoplasmic reticulum GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0001824///blastocyst development+++GO:0006508///proteolysis+++GO:0007520///myoblast fusion+++GO:0007565///female pregnancy+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0016540///protein autoprocessing+++GO:0032675///regulation of interleukin-6 production+++GO:0035458///cellular response to interferon-beta+++GO:0042542///response to hydrogen peroxide+++GO:0048266///behavioral response to pain+++GO:0051493///regulation of cytoskeleton organization+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:1901216///positive regulation of neuron death+++GO:1901741///positive regulation of myoblast fusion+++GO:2001247///positive regulation of phosphatidylcholine biosynthetic process 12335 12335 'Capn3' mRNA 25 31 18 0.49 0.62 0.36 0.28 0.31 0.23 0.49 0.273333333 16 18 13 24.66666667 15.66666667 0.296136239 -0.657440778 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0032991///protein-containing complex GO:0003824///catalytic activity+++GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008307///structural constituent of muscle+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0031402///sodium ion binding+++GO:0031432///titin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0055103///ligase regulator activity+++GO:0060090///molecular adaptor activity "GO:0006508///proteolysis+++GO:0012501///programmed cell death+++GO:0014718///positive regulation of satellite cell activation involved in skeletal muscle regeneration+++GO:0014850///response to muscle activity+++GO:0030163///protein catabolic process+++GO:0030239///myofibril assembly+++GO:0031648///protein destabilization+++GO:0033234///negative regulation of protein sumoylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045214///sarcomere organization+++GO:0045661///regulation of myoblast differentiation+++GO:0045862///positive regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050790///regulation of catalytic activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051592///response to calcium ion+++GO:0061061///muscle structure development+++GO:0065003///protein-containing complex assembly+++GO:0070315///G1 to G0 transition involved in cell differentiation+++GO:0071277///cellular response to calcium ion+++GO:0071472///cellular response to salt stress+++GO:0072657///protein localization to membrane+++GO:0097264///self proteolysis+++GO:1990091///sodium-dependent self proteolysis+++GO:1990092///calcium-dependent self proteolysis+++GO:2001015///negative regulation of skeletal muscle cell differentiation" 12336 12336 'Capns1' mRNA 1674 1708 1273 63.08 63.56 50.79 102.52 102.79 101.49 59.14333333 102.2666667 3135 3070 3009 1551.666667 3071.333333 3.81E-33 0.9788097 05131///Shigellosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006508///proteolysis 12337 12337 'Capn5' mRNA 796 701 749 9.7 8.37 9.68 6.99 6.63 6.61 9.25 6.743333333 665 611 602 748.6666667 626 0.017358362 -0.271739317 GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0045202///synapse GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 12338 12338 'Capn6' mRNA 213 235 233 3.26 3.53 3.78 3.81 3.89 4.27 3.523333333 3.99 287 286 311 227 294.6666667 0.030435435 0.363819117 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0048471///perinuclear region of cytoplasm GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0001578///microtubule bundle formation+++GO:0006508///proteolysis+++GO:0051493///regulation of cytoskeleton organization 12339 12339 'Capn7' mRNA 1056 1147 1042 15.74 16.78 16.45 13.37 12.99 14.3 16.32333333 13.55333333 1034 979 1071 1081.666667 1028 0.424111794 -0.084600833 GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0004175///endopeptidase activity+++GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0090541///MIT domain binding GO:0006508///proteolysis+++GO:0010634///positive regulation of epithelial cell migration+++GO:0097264///self proteolysis 12340 12340 'Capza1' mRNA 2381 2618 2591 40.85 44.18 47.14 72.36 67.72 66.12 44.05666667 68.73333333 4845 4435 4290 2530 4523.333333 1.17E-30 0.824156081 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0008290///F-actin capping protein complex+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton+++GO:0071203///WASH complex GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0030036///actin cytoskeleton organization+++GO:0034329///cell junction assembly+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping 12343 12343 'Capza2' mRNA 2827 2980 2965 62.73 65.1 69.79 118.56 118.53 118.02 65.87333333 118.37 6146 6000 5923 2924 6023 3.32E-62 1.029482281 04144///Endocytosis GO:0005829///cytosol+++GO:0005903///brush border+++GO:0008290///F-actin capping protein complex+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0030036///actin cytoskeleton organization+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping 12345 12345 'Capzb' mRNA 2975 2954 2927 102.5 100.23 107 246.94 247.72 244.66 103.2433333 246.44 8207 8045 7872 2952 8041.333333 2.68E-144 1.433374227 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0008290///F-actin capping protein complex+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030863///cortical cytoskeleton+++GO:0032279///asymmetric synapse+++GO:0033150///cytoskeletal calyx+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0061827///sperm head+++GO:0071203///WASH complex+++GO:0097224///sperm connecting piece+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0048487///beta-tubulin binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0008154///actin polymerization or depolymerization+++GO:0010591///regulation of lamellipodium assembly+++GO:0022604///regulation of cell morphogenesis+++GO:0030030///cell projection organization+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031175///neuron projection development+++GO:0048747///muscle fiber development+++GO:0051016///barbed-end actin filament capping+++GO:0051490///negative regulation of filopodium assembly+++GO:0051693///actin filament capping+++GO:0055001///muscle cell development+++GO:0090036///regulation of protein kinase C signaling 12346 12346 'Car1' mRNA 17 7 10 0.88 0.31 0.55 0.63 0.56 0.8 0.58 0.663333333 14 12 17 11.33333333 14.33333333 0.729260299 0.32726149 00910///Nitrogen metabolism GO:0005737///cytoplasm GO:0004064///arylesterase activity+++GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process 12348 12348 'Car11' mRNA 554 502 508 15.35 13.5 15.44 16.62 15.41 13.93 14.76333333 15.32 612 553 509 521.3333333 558 0.573678376 0.085168212 GO:0005576///extracellular region+++GO:0016323///basolateral plasma membrane GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016836///hydro-lyase activity GO:0006730///one-carbon metabolic process 12349 12349 'Car2' mRNA 3073 3236 2899 102.17 106.55 103.53 180.8 186.55 177.53 104.0833333 181.6266667 6145 6187 5848 3069.333333 6060 2.62E-65 0.971061765 00910///Nitrogen metabolism+++04964///Proximal tubule bicarbonate reclamation+++04966///Collecting duct acid secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0043209///myelin sheath+++GO:0045177///apical part of cell GO:0004064///arylesterase activity+++GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding "GO:0001822///kidney development+++GO:0002009///morphogenesis of an epithelium+++GO:0006730///one-carbon metabolic process+++GO:0006885///regulation of pH+++GO:0009268///response to pH+++GO:0010033///response to organic substance+++GO:0010043///response to zinc ion+++GO:0015670///carbon dioxide transport+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032849///positive regulation of cellular pH reduction+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043627///response to estrogen+++GO:0044070///regulation of anion transport+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0046903///secretion+++GO:0048545///response to steroid hormone+++GO:0051453///regulation of intracellular pH+++GO:0071498///cellular response to fluid shear stress+++GO:2001150///positive regulation of dipeptide transmembrane transport+++GO:2001225///regulation of chloride transport" 12350 12350 'Car3' mRNA 20965 22779 21978 803.08 860.55 893.17 2525.53 2653.19 2481.86 852.2666667 2553.526667 75740 77643 72009 21907.33333 75130.66667 3.27E-210 1.765603711 00910///Nitrogen metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016151///nickel cation binding+++GO:0016791///phosphatase activity+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0006979///response to oxidative stress+++GO:0009617///response to bacterium+++GO:0016311///dephosphorylation+++GO:0045471///response to ethanol 12351 12351 'Car4' mRNA 62 76 55 2.89 3.46 2.72 4.18 3.45 3.52 3.023333333 3.716666667 103 83 84 64.33333333 90 0.125507074 0.475066169 00910///Nitrogen metabolism+++04964///Proximal tubule bicarbonate reclamation GO:0005791///rough endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0031526///brush border membrane+++GO:0042383///sarcolemma+++GO:0046658///anchored component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome GO:0004089///carbonate dehydratase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0006885///regulation of pH+++GO:0015670///carbon dioxide transport+++GO:0015701///bicarbonate transport 12352 12352 'Car5a' mRNA 4.91 1.35 5.44 0.24 0.06 0.28 0.3 0.26 0.18 0.193333333 0.246666667 7.04 5.87 4.09 3.9 5.666666667 0.676970433 0.646144828 00910///Nitrogen metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006094///gluconeogenesis+++GO:0006730///one-carbon metabolic process 12353 12353 'Car6' mRNA 4 3 0 0.18 0.13 0 0.91 0.74 1.3 0.103333333 0.983333333 24 19 33 2.333333333 25.33333333 7.20E-05 3.442706788 00910///Nitrogen metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006730///one-carbon metabolic process 12354 12354 'Car7' mRNA 1386 1425 1358 51.45 51.76 53.76 6.89 5.64 6.69 52.32333333 6.406666667 218 170 203 1389.666667 197 2.45E-148 -2.831438755 00910///Nitrogen metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding "GO:0006730///one-carbon metabolic process+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032849///positive regulation of cellular pH reduction+++GO:0051453///regulation of intracellular pH+++GO:2001225///regulation of chloride transport" 12355 12355 'Nr1i3' mRNA 1.03 1.01 1.14 0.05 0.05 0.03 0.02 0.05 0.07 0.043333333 0.046666667 1.11 2.2 3.29 1.06 2.2 0.695559642 0.993445611 05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 12359 12359 'Cat' mRNA 2592 2693 2673 56.51 57.8 61.82 54.31 50.64 55.17 58.71 53.37333333 2865 2609 2818 2652.666667 2764 0.610583174 0.04591836 00380///Tryptophan metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++04068///FoxO signaling pathway+++04146///Peroxisome+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000268///peroxisome targeting sequence binding+++GO:0004046///aminoacylase activity+++GO:0004096///catalase activity+++GO:0004601///peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050661///NADP binding" GO:0000302///response to reactive oxygen species+++GO:0001657///ureteric bud development+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0006641///triglyceride metabolic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0008203///cholesterol metabolic process+++GO:0009060///aerobic respiration+++GO:0009642///response to light intensity+++GO:0009650///UV protection+++GO:0010193///response to ozone+++GO:0010288///response to lead ion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0014854///response to inactivity+++GO:0020027///hemoglobin metabolic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032355///response to estradiol+++GO:0032868///response to insulin+++GO:0033189///response to vitamin A+++GO:0033197///response to vitamin E+++GO:0033591///response to L-ascorbic acid+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0046686///response to cadmium ion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051781///positive regulation of cell division+++GO:0055093///response to hyperoxia+++GO:0070542///response to fatty acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0080184///response to phenylpropanoid 12361 12361 'Cask' mRNA 1247 1302 1247 7.73 7.97 8.24 4.34 4.38 4.13 7.98 4.283333333 799 791 741 1265.333333 777 2.86E-16 -0.715537362 GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005652///nuclear lamina+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016363///nuclear matrix+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060170///ciliary membrane+++GO:0097060///synaptic membrane+++GO:0097440///apical dendrite+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098846///podocyte foot GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030165///PDZ domain binding+++GO:0042043///neurexin family protein binding+++GO:0044877///protein-containing complex binding GO:0001953///negative regulation of cell-matrix adhesion+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016310///phosphorylation+++GO:0032024///positive regulation of insulin secretion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061045///negative regulation of wound healing+++GO:0070509///calcium ion import+++GO:0072659///protein localization to plasma membrane+++GO:0090280///positive regulation of calcium ion import+++GO:0090288///negative regulation of cellular response to growth factor stimulus+++GO:2000300///regulation of synaptic vesicle exocytosis 12362 12362 'Casp1' mRNA 20 16 26 0.78 0.62 1.08 8.96 7.13 7.58 0.826666667 7.89 264 205 216 20.66666667 228.3333333 1.70E-34 3.447824757 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++05014///Amyotrophic lateral sclerosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05164///Influenza A+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0072557///IPAF inflammasome complex+++GO:0072558///NLRP1 inflammasome complex+++GO:0072559///NLRP3 inflammasome complex+++GO:0097169///AIM2 inflammasome complex+++GO:0097179///protease inhibitor complex GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0050700///CARD domain binding+++GO:0097110///scaffold protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis "GO:0001666///response to hypoxia+++GO:0001774///microglial cell activation+++GO:0001819///positive regulation of cytokine production+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007520///myoblast fusion+++GO:0007613///memory+++GO:0009410///response to xenobiotic stimulus+++GO:0009617///response to bacterium+++GO:0010506///regulation of autophagy+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0016540///protein autoprocessing+++GO:0032496///response to lipopolysaccharide+++GO:0032611///interleukin-1 beta production+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0033198///response to ATP+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0050727///regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051882///mitochondrial depolarization+++GO:0060081///membrane hyperpolarization+++GO:0070269///pyroptosis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071310///cellular response to organic substance+++GO:0071346///cellular response to interferon-gamma+++GO:0097190///apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:0097300///programmed necrotic cell death+++GO:1901998///toxin transport+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway" 12363 12363 'Casp4' mRNA 36 47 30 1.63 2 1.39 9.09 8.49 10.14 1.673333333 9.24 225 211 232 37.66666667 222.6666667 2.58E-26 2.556068514 04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0061702///inflammasome complex+++GO:0072557///IPAF inflammasome complex+++GO:0072558///NLRP1 inflammasome complex+++GO:0072559///NLRP3 inflammasome complex+++GO:0097169///AIM2 inflammasome complex GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0050700///CARD domain binding+++GO:0097110///scaffold protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0007015///actin filament organization+++GO:0012501///programmed cell death+++GO:0016540///protein autoprocessing+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035234///ectopic germ cell programmed cell death+++GO:0042981///regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070269///pyroptosis+++GO:0097190///apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1904646///cellular response to amyloid-beta 12364 12364 'Casp12' mRNA 210 195 184 5.02 4.61 4.77 9.61 9.52 9.86 4.8 9.663333333 455 443 453 196.3333333 450.3333333 1.66E-17 1.187017618 04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04621///NOD-like receptor signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05161///Hepatitis B GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072557///IPAF inflammasome complex+++GO:0072559///NLRP3 inflammasome complex+++GO:0097169///AIM2 inflammasome complex GO:0002020///protease binding+++GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0010663///positive regulation of striated muscle cell apoptotic process+++GO:0016540///protein autoprocessing+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050727///regulation of inflammatory response+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:0097264///self proteolysis 12365 12365 'Casp14' mRNA 0 0 1 0 0 0.03 0.04 0.11 0.06 0.01 0.07 2 5 3 0.333333333 3.333333333 0.158893851 3.213689821 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0045095///keratin filament GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0006508///proteolysis+++GO:0030154///cell differentiation+++GO:0070268///cornification+++GO:0097194///execution phase of apoptosis 12366 12366 'Casp2' mRNA 623 636 598 9.6 9.64 9.77 7.45 6.43 7.71 9.67 7.196666667 557 469 558 619 528 0.047574607 -0.241719159 04210///Apoptosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis "GO:0001554///luteolysis+++GO:0003407///neural retina development+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007420///brain development+++GO:0007568///aging+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0016485///protein processing+++GO:0035234///ectopic germ cell programmed cell death+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0097190///apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097194///execution phase of apoptosis+++GO:2001235///positive regulation of apoptotic signaling pathway" 12367 12367 'Casp3' mRNA 470 580 505 10.02 12.16 11.42 26.8 23.22 24.62 11.2 24.88 1449 1217 1285 518.3333333 1317 1.40E-38 1.332831898 01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04115///p53 signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04726///Serotonergic synapse+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05222///Small cell lung cancer+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031264///death-inducing signaling complex+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016005///phospholipase A2 activator activity+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0001554///luteolysis+++GO:0001666///response to hypoxia+++GO:0001782///B cell homeostasis+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007413///axonal fasciculation+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0007611///learning or memory+++GO:0008627///intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:0009411///response to UV+++GO:0009611///response to wounding+++GO:0009749///response to glucose+++GO:0010033///response to organic substance+++GO:0010038///response to metal ion+++GO:0010165///response to X-ray+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0021766///hippocampus development+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0031647///regulation of protein stability+++GO:0032025///response to cobalt ion+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034349///glial cell apoptotic process+++GO:0035094///response to nicotine+++GO:0035556///intracellular signal transduction+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043200///response to amino acid+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045165///cell fate commitment+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045786///negative regulation of cell cycle+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0046677///response to antibiotic+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0051146///striated muscle cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0051402///neuron apoptotic process+++GO:0061713///anterior neural tube closure+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071310///cellular response to organic substance+++GO:0071407///cellular response to organic cyclic compound+++GO:0071887///leukocyte apoptotic process+++GO:0072734///cellular response to staurosporine+++GO:0097194///execution phase of apoptosis+++GO:1902004///positive regulation of amyloid-beta formation 12368 12368 'Casp6' mRNA 427 476 508 17.15 18.86 21.65 18.29 18.74 16.88 19.22 17.97 523 523 467 470.3333333 504.3333333 0.613236583 0.085775062 04210///Apoptosis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0002525///acute inflammatory response to non-antigenic stimulus+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007413///axonal fasciculation+++GO:0009749///response to glucose+++GO:0010039///response to iron ion+++GO:0030855///epithelial cell differentiation+++GO:0034097///response to cytokine+++GO:0042542///response to hydrogen peroxide+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046670///positive regulation of retinal cell programmed cell death+++GO:0072734///cellular response to staurosporine+++GO:0097194///execution phase of apoptosis 12369 12369 'Casp7' mRNA 256 310 222 5.82 6.74 5.59 7.92 7.49 9.08 6.05 8.163333333 384 355 428 262.6666667 389 3.87E-04 0.559424724 04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05200///Pathways in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0004190///aspartic-type endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007507///heart development+++GO:0007568///aging+++GO:0009411///response to UV+++GO:0016485///protein processing+++GO:0051146///striated muscle cell differentiation+++GO:0051402///neuron apoptotic process+++GO:0071887///leukocyte apoptotic process+++GO:0072734///cellular response to staurosporine+++GO:0097194///execution phase of apoptosis 12370 12370 'Casp8' mRNA 350 475 462 8.34 10.71 11.46 25.63 24.52 26.06 10.17 25.40333333 1205 1145 1246 429 1198.666667 2.23E-34 1.468193122 01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05134///Legionellosis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030690///Noc1p-Noc2p complex+++GO:0031264///death-inducing signaling complex+++GO:0031265///CD95 death-inducing signaling complex+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0097342///ripoptosome GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005123///death receptor binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0035877///death effector domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0001525///angiogenesis+++GO:0001817///regulation of cytokine production+++GO:0001841///neural tube formation+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007507///heart development+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0016485///protein processing+++GO:0030225///macrophage differentiation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0034612///response to tumor necrosis factor+++GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045088///regulation of innate immune response+++GO:0045471///response to ethanol+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045862///positive regulation of proteolysis+++GO:0048738///cardiac muscle tissue development+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070243///regulation of thymocyte apoptotic process+++GO:0070269///pyroptosis+++GO:0071260///cellular response to mechanical stimulus+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0097264///self proteolysis+++GO:0097284///hepatocyte apoptotic process+++GO:1901216///positive regulation of neuron death+++GO:2001233///regulation of apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 12371 12371 'Casp9' mRNA 588 659 559 8.17 8.99 8.22 9.5 9.52 9.67 8.46 9.563333333 789 771 777 602 779 5.12E-04 0.361996284 01524///Platinum drug resistance+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04370///VEGF signaling pathway+++04919///Thyroid hormone signaling pathway+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05134///Legionellosis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043293///apoptosome GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0001822///kidney development+++GO:0002931///response to ischemia+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007568///aging+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009411///response to UV+++GO:0014070///response to organic cyclic compound+++GO:0032025///response to cobalt ion+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034349///glial cell apoptotic process+++GO:0034644///cellular response to UV+++GO:0042770///signal transduction in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046677///response to antibiotic+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071407///cellular response to organic cyclic compound+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071887///leukocyte apoptotic process+++GO:0097194///execution phase of apoptosis+++GO:2001020///regulation of response to DNA damage stimulus 12372 12372 'Casq1' mRNA 81 69 59 2.48 2.08 1.92 2.05 2.15 1.9 2.16 2.033333333 77 79 69 69.66666667 75 0.808879305 0.098363482 04020///Calcium signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0014802///terminal cisterna+++GO:0014804///terminal cisterna lumen+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0031674///I band+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006937///regulation of muscle contraction+++GO:0007029///endoplasmic reticulum organization+++GO:0007519///skeletal muscle tissue development+++GO:0009408///response to heat+++GO:0010033///response to organic substance+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014809///regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion+++GO:0014870///response to muscle inactivity+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0045214///sarcomere organization+++GO:0051258///protein polymerization+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051282///regulation of sequestering of calcium ion+++GO:1901341///positive regulation of store-operated calcium channel activity+++GO:2001256///regulation of store-operated calcium entry 12373 12373 'Casq2' mRNA 14 24 15 0.3 0.51 0.35 0.64 0.15 0.41 0.386666667 0.4 34 8 21 17.66666667 21 0.78770481 0.233244674 04020///Calcium signaling pathway+++04260///Cardiac muscle contraction GO:0005737///cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030314///junctional membrane complex+++GO:0033018///sarcoplasmic reticulum lumen GO:0005080///protein kinase C binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0002027///regulation of heart rate+++GO:0006937///regulation of muscle contraction+++GO:0010649///regulation of cell communication by electrical coupling+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0043267///negative regulation of potassium ion transport+++GO:0045214///sarcomere organization+++GO:0051208///sequestering of calcium ion+++GO:0051258///protein polymerization+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0060048///cardiac muscle contraction+++GO:0060306///regulation of membrane repolarization+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0071313///cellular response to caffeine+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity 12374 12374 'Casr' mRNA 35 14 13 0.24 0.1 0.1 0.01 0.01 0.01 0.146666667 0.01 1 2 2 20.66666667 1.666666667 2.72E-04 -3.632598485 "04621///NOD-like receptor signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus GO:0004930///G protein-coupled receptor activity+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0016597///amino acid binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0002931///response to ischemia+++GO:0005513///detection of calcium ion+++GO:0006874///cellular calcium ion homeostasis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007254///JNK cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0010038///response to metal ion+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0032024///positive regulation of insulin secretion+++GO:0032781///positive regulation of ATPase activity+++GO:0032782///bile acid secretion+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042311///vasodilation+++GO:0045907///positive regulation of vasoconstriction+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051592///response to calcium ion+++GO:0051924///regulation of calcium ion transport+++GO:0060613///fat pad development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070509///calcium ion import+++GO:0071305///cellular response to vitamin D+++GO:0071333///cellular response to glucose stimulus+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071774///response to fibroblast growth factor+++GO:0090280///positive regulation of calcium ion import+++GO:1901653///cellular response to peptide+++GO:1902476///chloride transmembrane transport 12380 12380 'Cast' mRNA 1139.14 1233.82 1204.66 14.96 15.91 16.84 20.68 20.47 20.03 15.90333333 20.39333333 1877.35 1781.58 1788.49 1192.54 1815.806667 5.85E-14 0.59393051 05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0002020///protease binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0010859///calcium-dependent cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0007343///egg activation+++GO:0010466///negative regulation of peptidase activity+++GO:0030163///protein catabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0051726///regulation of cell cycle+++GO:0071157///negative regulation of cell cycle arrest+++GO:0097340///inhibition of cysteine-type endopeptidase activity+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process 12385 12385 'Ctnna1' mRNA 4772.56 4996.48 5058.59 70.52 72.67 79.4 78.96 76.97 80.27 74.19666667 78.73333333 6144.85 5856.39 6051.49 4942.543333 6017.576667 3.03E-05 0.2702284 04390///Hippo signaling pathway+++04520///Adherens junction+++04670///Leukocyte transendothelial migration+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0014704///intercalated disc+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016342///catenin complex+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0017166///vinculin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0051015///actin filament binding GO:0001541///ovarian follicle development+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007568///aging+++GO:0008584///male gonad development+++GO:0014070///response to organic cyclic compound+++GO:0016264///gap junction assembly+++GO:0016477///cell migration+++GO:0031103///axon regeneration+++GO:0034613///cellular protein localization+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0043297///apical junction assembly+++GO:0043627///response to estrogen+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048854///brain morphogenesis+++GO:0071681///cellular response to indole-3-methanol+++GO:0090136///epithelial cell-cell adhesion+++GO:0098609///cell-cell adhesion+++GO:1900181///negative regulation of protein localization to nucleus+++GO:2000146///negative regulation of cell motility+++GO:2001045///negative regulation of integrin-mediated signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 12386 12386 'Ctnna2' mRNA 183 166 131 2.5 2.21 1.89 0.16 0.38 0.21 2.2 0.25 14 31 17 160 20.66666667 4.95E-20 -2.955441559 04390///Hippo signaling pathway+++04520///Adherens junction+++04670///Leukocyte transendothelial migration+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016342///catenin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0099092///postsynaptic density, intracellular component" GO:0005198///structural molecule activity+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0010975///regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0030154///cell differentiation+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0048813///dendrite morphogenesis+++GO:0048854///brain morphogenesis+++GO:0051823///regulation of synapse structural plasticity+++GO:0060134///prepulse inhibition+++GO:0090136///epithelial cell-cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:2001222///regulation of neuron migration 12387 12387 'Ctnnb1' mRNA 6551 6896 4429 102.89 106.11 74.42 75.8 84.32 82.32 94.47333333 80.81333333 5502 6013 5825 5958.666667 5780 0.863090843 -0.044982831 04015///Rap1 signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04670///Leukocyte transendothelial migration+++04916///Melanogenesis+++04919///Thyroid hormone signaling pathway+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++05160///Hepatitis C+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05418///Fluid shear stress and atherosclerosis "GO:0000791///euchromatin+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005916///fascia adherens+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0016600///flotillin complex+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030877///beta-catenin destruction complex+++GO:0031253///cell projection membrane+++GO:0031528///microvillus membrane+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0034750///Scrib-APC-beta-catenin complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043198///dendritic shaft+++GO:0043296///apical junction complex+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0070369///beta-catenin-TCF7L2 complex+++GO:0071944///cell periphery+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0099092///postsynaptic density, intracellular component+++GO:1990907///beta-catenin-TCF complex+++GO:1990909///Wnt signalosome" GO:0001221///transcription cofactor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030331///estrogen receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0046332///SMAD binding+++GO:0050998///nitric-oxide synthase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070411///I-SMAD binding+++GO:0097718///disordered domain specific binding+++GO:1990226///histone methyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0000578///embryonic axis specification+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0001501///skeletal system development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001702///gastrulation with mouth forming second+++GO:0001706///endoderm formation+++GO:0001708///cell fate specification+++GO:0001709///cell fate determination+++GO:0001711///endodermal cell fate commitment+++GO:0001764///neuron migration+++GO:0001822///kidney development+++GO:0001840///neural plate development+++GO:0001894///tissue homeostasis+++GO:0001944///vasculature development+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003266///regulation of secondary heart field cardioblast proliferation+++GO:0003338///metanephros morphogenesis+++GO:0003340///negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007398///ectoderm development+++GO:0007399///nervous system development+++GO:0007403///glial cell fate determination+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009948///anterior/posterior axis specification+++GO:0009950///dorsal/ventral axis specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0009987///cellular process+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010909///positive regulation of heparan sulfate proteoglycan biosynthetic process+++GO:0014010///Schwann cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0016525///negative regulation of angiogenesis+++GO:0021819///layer formation in cerebral cortex+++GO:0022009///central nervous system vasculogenesis+++GO:0022405///hair cycle process+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030217///T cell differentiation+++GO:0030316///osteoclast differentiation+++GO:0030324///lung development+++GO:0030539///male genitalia development+++GO:0030856///regulation of epithelial cell differentiation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0030997///regulation of centriole-centriole cohesion+++GO:0031016///pancreas development+++GO:0031069///hair follicle morphogenesis+++GO:0031641///regulation of myelination+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032355///response to estradiol+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033077///T cell differentiation in thymus+++GO:0033234///negative regulation of protein sumoylation+++GO:0034097///response to cytokine+++GO:0034332///adherens junction organization+++GO:0034333///adherens junction assembly+++GO:0034394///protein localization to cell surface+++GO:0034613///cellular protein localization+++GO:0035050///embryonic heart tube development+++GO:0035112///genitalia morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0036520///astrocyte-dopaminergic neuron signaling+++GO:0042127///regulation of cell proliferation+++GO:0042129///regulation of T cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0043627///response to estrogen+++GO:0044093///positive regulation of molecular function+++GO:0044334///canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition+++GO:0044338///canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation+++GO:0045453///bone resorption+++GO:0045595///regulation of cell differentiation+++GO:0045596///negative regulation of cell differentiation+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045976///negative regulation of mitotic cell cycle, embryonic+++GO:0048469///cell maturation+++GO:0048489///synaptic vesicle transport+++GO:0048513///animal organ development+++GO:0048538///thymus development+++GO:0048568///embryonic organ development+++GO:0048599///oocyte development+++GO:0048617///embryonic foregut morphogenesis+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0050768///negative regulation of neurogenesis+++GO:0050808///synapse organization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051145///smooth muscle cell differentiation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051884///regulation of timing of anagen+++GO:0051973///positive regulation of telomerase activity+++GO:0060038///cardiac muscle cell proliferation+++GO:0060066///oviduct development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060173///limb development+++GO:0060439///trachea morphogenesis+++GO:0060440///trachea formation+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060479///lung cell differentiation+++GO:0060484///lung-associated mesenchyme development+++GO:0060485///mesenchyme development+++GO:0060492///lung induction+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0060769///positive regulation of epithelial cell proliferation involved in prostate gland development+++GO:0060789///hair follicle placode formation+++GO:0060916///mesenchymal cell proliferation involved in lung development+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0060982///coronary artery morphogenesis+++GO:0060983///epicardium-derived cardiac vascular smooth muscle cell differentiation+++GO:0061047///positive regulation of branching involved in lung morphogenesis+++GO:0061154///endothelial tube morphogenesis+++GO:0061198///fungiform papilla formation+++GO:0061324///canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation+++GO:0061549///sympathetic ganglion development+++GO:0061550///cranial ganglion development+++GO:0070602///regulation of centromeric sister chromatid cohesion+++GO:0071260///cellular response to mechanical stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0071681///cellular response to indole-3-methanol+++GO:0072033///renal vesicle formation+++GO:0072053///renal inner medulla development+++GO:0072054///renal outer medulla development+++GO:0072079///nephron tubule formation+++GO:0072132///mesenchyme morphogenesis+++GO:0072182///regulation of nephron tubule epithelial cell differentiation+++GO:0090279///regulation of calcium ion import+++GO:0097091///synaptic vesicle clustering+++GO:0098609///cell-cell adhesion+++GO:1901215///negative regulation of neuron death+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1904796///regulation of core promoter binding+++GO:1904798///positive regulation of core promoter binding+++GO:1904888///cranial skeletal system development+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1904954///canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation+++GO:1990138///neuron projection extension+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:1990403///embryonic brain development+++GO:1990791///dorsal root ganglion development+++GO:2000008///regulation of protein localization to cell surface+++GO:2000017///positive regulation of determination of dorsal identity+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2001234///negative regulation of apoptotic signaling pathway" 12388 12388 'Ctnnd1' mRNA 5197.68 5214.05 5004.81 44.48 43.7 45.2 44.62 41.11 42.93 44.46 42.88666667 5612.99 5037.31 5332.47 5138.846667 5327.59 0.592804009 0.039485631 04015///Rap1 signaling pathway+++04520///Adherens junction+++04670///Leukocyte transendothelial migration "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016342///catenin complex+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0045296///cadherin binding+++GO:0050839///cell adhesion molecule binding GO:0001738///morphogenesis of a polarized epithelium+++GO:0001822///kidney development+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007435///salivary gland morphogenesis+++GO:0010954///positive regulation of protein processing+++GO:0016055///Wnt signaling pathway+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050821///protein stabilization+++GO:0060690///epithelial cell differentiation involved in salivary gland development+++GO:0072102///glomerulus morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation 12389 12389 'Cav1' mRNA 1821 1951 1822 42.05 43.79 44.51 66.86 65.77 67.73 43.45 66.78666667 3403 3203 3254 1864.666667 3286.666667 2.26E-36 0.805780055 04144///Endocytosis+++04510///Focal adhesion+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05205///Proteoglycans in cancer+++05416///Viral myocarditis+++05418///Fluid shear stress and atherosclerosis GO:0000139///Golgi membrane+++GO:0002080///acrosomal membrane+++GO:0002095///caveolar macromolecular signaling complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0005929///cilium+++GO:0005938///cell cortex+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm "GO:0000149///SNARE binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016504///peptidase activator activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019905///syntaxin binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding+++GO:0033612///receptor serine/threonine kinase binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0050998///nitric-oxide synthase binding+++GO:0051117///ATPase binding+++GO:0060090///molecular adaptor activity+++GO:0070320///inward rectifier potassium channel inhibitor activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0002026///regulation of the force of heart contraction+++GO:0002931///response to ischemia+++GO:0003057///regulation of the force of heart contraction by chemical signal+++GO:0006641///triglyceride metabolic process+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006897///endocytosis+++GO:0006940///regulation of smooth muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0007595///lactation+++GO:0008104///protein localization+++GO:0008285///negative regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0009967///positive regulation of signal transduction+++GO:0009968///negative regulation of signal transduction+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010952///positive regulation of peptidase activity+++GO:0015031///protein transport+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019915///lipid storage+++GO:0030154///cell differentiation+++GO:0030193///regulation of blood coagulation+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030879///mammary gland development+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031295///T cell costimulation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031623///receptor internalization+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032507///maintenance of protein location in cell+++GO:0032570///response to progesterone+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033344///cholesterol efflux+++GO:0033484///nitric oxide homeostasis+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0038016///insulin receptor internalization+++GO:0042060///wound healing+++GO:0042310///vasoconstriction+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042632///cholesterol homeostasis+++GO:0043085///positive regulation of catalytic activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0043627///response to estrogen+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045807///positive regulation of endocytosis+++GO:0045907///positive regulation of vasoconstriction+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0046785///microtubule polymerization+++GO:0048550///negative regulation of pinocytosis+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051592///response to calcium ion+++GO:0051899///membrane depolarization+++GO:0052547///regulation of peptidase activity+++GO:0055074///calcium ion homeostasis+++GO:0060056///mammary gland involution+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0060546///negative regulation of necroptotic process+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070836///caveola assembly+++GO:0071260///cellular response to mechanical stimulus+++GO:0071360///cellular response to exogenous dsRNA+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071455///cellular response to hyperoxia+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071711///basement membrane organization+++GO:0072584///caveolin-mediated endocytosis+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086098///angiotensin-activated signaling pathway involved in heart process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090398///cellular senescence+++GO:0097190///apoptotic signaling pathway+++GO:0098903///regulation of membrane repolarization during action potential+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900027///regulation of ruffle assembly+++GO:1900085///negative regulation of peptidyl-tyrosine autophosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1903598///positive regulation of gap junction assembly+++GO:1903609///negative regulation of inward rectifier potassium channel activity+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:2000535///regulation of entry of bacterium into host cell+++GO:2000811///negative regulation of anoikis+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:2001258///negative regulation of cation channel activity 12390 12390 'Cav2' mRNA 1080 1251 1070 22.27 25.58 23.31 24.64 25.83 27.14 23.72 25.87 1378 1427 1458 1133.666667 1421 3.82E-04 0.316301141 04144///Endocytosis+++04510///Focal adhesion+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0000139///Golgi membrane+++GO:0002080///acrosomal membrane+++GO:0002095///caveolar macromolecular signaling complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm "GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019905///syntaxin binding+++GO:0030674///protein binding, bridging+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0031748///D1 dopamine receptor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051219///phosphoprotein binding+++GO:0060090///molecular adaptor activity+++GO:0097110///scaffold protein binding" GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006897///endocytosis+++GO:0006906///vesicle fusion+++GO:0007005///mitochondrion organization+++GO:0007029///endoplasmic reticulum organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0007268///chemical synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0016050///vesicle organization+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0043410///positive regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0044794///positive regulation by host of viral process+++GO:0048278///vesicle docking+++GO:0048741///skeletal muscle fiber development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060161///positive regulation of dopamine receptor signaling pathway+++GO:0070836///caveola assembly+++GO:0071711///basement membrane organization+++GO:1900182///positive regulation of protein localization to nucleus 12393 12393 'Runx2' mRNA 112 87 60.95 0.97 0.74 0.57 1.46 1.16 1.17 0.76 1.263333333 188 148 149 86.65 161.6666667 4.63E-04 0.898931142 "04928///Parathyroid hormone synthesis, secretion and action+++05202///Transcriptional misregulation in cancer" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0042826///histone deacetylase binding+++GO:0043425///bHLH transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001958///endochondral ossification+++GO:0002051///osteoblast fate commitment+++GO:0002062///chondrocyte differentiation+++GO:0002063///chondrocyte development+++GO:0002076///osteoblast development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030217///T cell differentiation+++GO:0030278///regulation of ossification+++GO:0030509///BMP signaling pathway+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0045595///regulation of cell differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048863///stem cell differentiation+++GO:0071773///cellular response to BMP stimulus+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" 12394 12394 'Runx1' mRNA 219 222 192 1.64 1.62 1.53 5.09 4.99 5.61 1.596666667 5.23 770 723 815 211 769.3333333 9.18E-53 1.856450258 04530///Tight junction+++04659///Th17 cell differentiation+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia GO:0000785///chromatin+++GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016513///core-binding factor complex+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0070491///repressing transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0002062///chondrocyte differentiation+++GO:0002318///myeloid progenitor cell differentiation+++GO:0002573///myeloid leukocyte differentiation+++GO:0002667///regulation of T cell anergy+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0009966///regulation of signal transduction+++GO:0030097///hemopoiesis+++GO:0030099///myeloid cell differentiation+++GO:0030182///neuron differentiation+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0032526///response to retinoic acid+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0035162///embryonic hemopoiesis+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048266///behavioral response to pain+++GO:0048663///neuron fate commitment+++GO:0048666///neuron development+++GO:0060216///definitive hemopoiesis+++GO:0071336///regulation of hair follicle cell proliferation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1903431///positive regulation of cell maturation+++GO:2000872///positive regulation of progesterone secretion" 12395 12395 'Runx1t1' mRNA 722 658 666 4.37 3.86 4.3 1.31 1.41 1.33 4.176666667 1.35 251 247 238 682 245.3333333 3.40E-34 -1.487156891 05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010977///negative regulation of neuron projection development+++GO:0045444///fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051101///regulation of DNA binding" 12396 12396 'Cbfa2t2' mRNA 980.03 964.19 1128.8 8.54 8.28 10.45 5.29 5.19 5.43 9.09 5.303333333 698.64 670 695.35 1024.34 687.9966667 1.26E-07 -0.59092255 GO:0005634///nucleus GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0030855///epithelial cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060575///intestinal epithelial cell differentiation" 12398 12398 'Cbfa2t3' mRNA 85 72 57 0.78 0.62 0.42 0.67 0.77 0.76 0.606666667 0.733333333 114 126 124 71.33333333 121.3333333 0.004339108 0.760387453 GO:0000139///Golgi membrane+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0006351///transcription, DNA-templated+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0030851///granulocyte differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045820///negative regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1903715///regulation of aerobic respiration" 12399 12399 'Runx3' mRNA 13.05 13.01 4 0.2 0.19 0.07 2.14 1.87 2.4 0.153333333 2.136666667 153.13 132.15 169.98 10.02 151.7533333 2.65E-25 3.915166044 04658///Th1 and Th2 cell differentiation+++05169///Epstein-Barr virus infection GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016513///core-binding factor complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042826///histone deacetylase binding+++GO:0046332///SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007411///axon guidance+++GO:0030097///hemopoiesis+++GO:0030182///neuron differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0031175///neuron projection development+++GO:0032609///interferon-gamma production+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0071559///response to transforming growth factor beta+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 12400 12400 'Cbfb' mRNA 568 531 442 10.79 9.95 8.93 13.22 13.63 12.18 9.89 13.01 794 796 712 513.6666667 767.3333333 5.11E-07 0.570813546 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016513///core-binding factor complex+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030098///lymphocyte differentiation+++GO:0030099///myeloid cell differentiation+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0060216///definitive hemopoiesis" 12401 12401 'Serpina6' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005496///steroid binding+++GO:0008289///lipid binding GO:0008211///glucocorticoid metabolic process+++GO:0010951///negative regulation of endopeptidase activity 12402 12402 'Cbl' mRNA 579 654 544 4.23 4.93 4.48 6.49 4.8 5.98 4.546666667 5.756666667 1062 751 962 592.3333333 925 3.13E-07 0.630941131 04012///ErbB signaling pathway+++04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04910///Insulin signaling pathway+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05220///Chronic myeloid leukemia GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016600///flotillin complex+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0001784///phosphotyrosine residue binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0046872///metal ion binding+++GO:0046875///ephrin receptor binding+++GO:0047690///aspartyltransferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:1990782///protein tyrosine kinase binding GO:0000209///protein polyubiquitination+++GO:0006468///protein phosphorylation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0008584///male gonad development+++GO:0010332///response to gamma radiation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0016567///protein ubiquitination+++GO:0023051///regulation of signaling+++GO:0032487///regulation of Rap protein signal transduction+++GO:0033574///response to testosterone+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042594///response to starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0043303///mast cell degranulation+++GO:0045453///bone resorption+++GO:0045471///response to ethanol+++GO:0046677///response to antibiotic+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0051865///protein autoubiquitination+++GO:0070997///neuron death+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:1901215///negative regulation of neuron death+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000583///regulation of platelet-derived growth factor receptor-alpha signaling pathway 12404 12404 'Cbln1' mRNA 22 34 18 0.53 0.8 0.46 0.29 0.34 0.32 0.596666667 0.316666667 14 16 15 24.66666667 15 0.255079006 -0.718942233 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043083///synaptic cleft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009306///protein secretion+++GO:0021707///cerebellar granule cell differentiation+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099558///maintenance of synapse structure+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1905606///regulation of presynapse assembly+++GO:1905703///negative regulation of inhibitory synapse assembly 12405 12405 'Cbln2' mRNA 0 0 1 0 0 0.02 0 0.1 0.1 0.006666667 0.066666667 0 5 5 0.333333333 3.333333333 0.195633743 3.221259872 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0098814///spontaneous synaptic transmission+++GO:0099558///maintenance of synapse structure+++GO:1905606///regulation of presynapse assembly 12406 12406 'Serpinh1' mRNA 2401 2421 1104 60.43 59.99 29.45 89.49 88.49 82.83 49.95666667 86.93666667 4086 3949 3660 1975.333333 3898.333333 0.004363462 0.985619772 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0045121///membrane raft+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0051082///unfolded protein binding GO:0003433///chondrocyte development involved in endochondral bone morphogenesis+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030199///collagen fibril organization+++GO:0032964///collagen biosynthetic process+++GO:0051604///protein maturation 12408 12408 'Cbr1' mRNA 1151 1232 1038 66.84 70.71 63.96 50.88 53.13 54 67.17 52.67 1005 1023 1031 1140.333333 1019.666667 0.069387882 -0.170310437 00590///Arachidonic acid metabolism+++00790///Folate biosynthesis+++00980///Metabolism of xenobiotics by cytochrome P450+++05204///Chemical carcinogenesis - DNA adducts+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0035003///subapical complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004090///carbonyl reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047021///15-hydroxyprostaglandin dehydrogenase (NADP+) activity+++GO:0050221///prostaglandin-E2 9-reductase activity" GO:0006706///steroid catabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0017144///drug metabolic process+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0042373///vitamin K metabolic process+++GO:0042376///phylloquinone catabolic process+++GO:1905344///prostaglandin catabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process 12409 12409 'Cbr2' mRNA 265 270 257 16.56 16.69 16.99 234.82 234.34 226.21 16.74666667 231.79 4304 4183 4006 264 4164.333333 0 3.968184596 00590///Arachidonic acid metabolism+++00980///Metabolism of xenobiotics by cytochrome P450 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0050038///L-xylulose reductase (NADP+) activity GO:0005997///xylulose metabolic process+++GO:0006006///glucose metabolic process+++GO:0006116///NADH oxidation 12411 12411 'Cbs' mRNA 386 354 333 8.83 7.89 7.98 6.21 7.33 6.35 8.233333333 6.63 317 365 314 357.6666667 332 0.510817512 -0.116763641 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids" GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004122///cystathionine beta-synthase activity+++GO:0016829///lyase activity+++GO:0019825///oxygen binding+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030170///pyridoxal phosphate binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050421///nitrite reductase (NO-forming) activity+++GO:0070025///carbon monoxide binding+++GO:0070026///nitric oxide binding+++GO:0072341///modified amino acid binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0001958///endochondral ossification+++GO:0001974///blood vessel remodeling+++GO:0006535///cysteine biosynthetic process from serine+++GO:0006563///L-serine metabolic process+++GO:0006565///L-serine catabolic process+++GO:0006801///superoxide metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0010749///regulation of nitric oxide mediated signal transduction+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0019344///cysteine biosynthetic process+++GO:0019346///transsulfuration+++GO:0019448///L-cysteine catabolic process+++GO:0021587///cerebellum morphogenesis+++GO:0031667///response to nutrient levels+++GO:0042262///DNA protection+++GO:0043066///negative regulation of apoptotic process+++GO:0043418///homocysteine catabolic process+++GO:0043506///regulation of JUN kinase activity+++GO:0050667///homocysteine metabolic process+++GO:0051593///response to folic acid+++GO:0060135///maternal process involved in female pregnancy+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:0071456///cellular response to hypoxia+++GO:0097746///regulation of blood vessel diameter 12412 12412 'Cbx1' mRNA 752 703 795 31.56 29.64 37.14 27.46 28.79 24.79 32.78 27.01333333 748 726 655 750 709.6666667 0.49514219 -0.094902386 "GO:0000775///chromosome, centromeric region+++GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin+++GO:0005819///spindle+++GO:0010369///chromocenter+++GO:0090734///site of DNA damage" GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0035064///methylated histone binding+++GO:0042802///identical protein binding+++GO:1990226///histone methyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated" 12416 12416 'Cbx2' mRNA 173 200 157 2.46 2.77 2.34 1.66 1.9 1.92 2.523333333 1.826666667 132 148 152 176.6666667 144 0.173887934 -0.302283275 GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0045137///development of primary sexual characteristics 12417 12417 'Cbx3' mRNA 3889 3607 4864 124.18 113.53 164.82 160.22 146.34 149.54 134.1766667 152.0333333 5762 5137 5207 4120 5368.666667 0.077643084 0.36040313 05131///Shigellosis "GO:0000775///chromosome, centromeric region+++GO:0000779///condensed chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0005819///spindle+++GO:0010369///chromocenter+++GO:0035985///senescence-associated heterochromatin focus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0090734///site of DNA damage" GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0035064///methylated histone binding+++GO:0042802///identical protein binding+++GO:1990226///histone methyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 12418 12418 'Cbx4' mRNA 322 308 244 3.31 3.11 2.66 2.01 2.01 2.14 3.026666667 2.053333333 225 220 233 291.3333333 226 0.028024122 -0.373624188 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019899///enzyme binding+++GO:0032183///SUMO binding+++GO:0035064///methylated histone binding+++GO:0051219///phosphoprotein binding+++GO:0061665///SUMO ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0016925///protein sumoylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050673///epithelial cell proliferation" 12419 12419 'Cbx5' mRNA 3203 3241 3327 40.54 36.11 41.34 36.83 42.74 39 39.33 39.52333333 3460 3180.05 3223 3257 3287.683333 0.998591786 -5.91E-04 "GO:0000118///histone deacetylase complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005730///nucleolus+++GO:0010369///chromocenter+++GO:0016605///PML body+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0035097///histone methyltransferase complex+++GO:0090734///site of DNA damage+++GO:1990904///ribonucleoprotein complex" "GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0035064///methylated histone binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0044877///protein-containing complex binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated" 12421 12421 'Rb1cc1' mRNA 1636 1792 733 14.67 16.6 6.17 5.55 7.64 8.63 12.48 7.273333333 805 1031 1095 1387 977 0.274838259 -0.495688506 04140///Autophagy - animal+++04211///Longevity regulating pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0000421///autophagosome membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0031965///nuclear membrane+++GO:0034045///phagophore assembly site membrane+++GO:1990316///Atg1/ULK1 kinase complex GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0060090///molecular adaptor activity GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0007507///heart development+++GO:0030242///autophagy of peroxisome+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0045793///positive regulation of cell size+++GO:0046330///positive regulation of JNK cascade+++GO:0061709///reticulophagy+++GO:0061723///glycophagy+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 12424 12424 'Cck' mRNA 4 2 2 0.33 0.21 0.15 0.36 0.46 0.19 0.23 0.336666667 5 6 2 2.666666667 4.333333333 0.684520637 0.693672558 04080///Neuroactive ligand-receptor interaction+++04911///Insulin secretion+++04972///Pancreatic secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043195///terminal bouton+++GO:0043203///axon hillock+++GO:0043204///perikaryon GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0005515///protein binding+++GO:0051428///peptide hormone receptor binding GO:0001764///neuron migration+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007409///axonogenesis+++GO:0007586///digestion+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0014049///positive regulation of glutamate secretion+++GO:0031334///positive regulation of protein complex assembly+++GO:0032099///negative regulation of appetite+++GO:0042755///eating behavior+++GO:0043065///positive regulation of apoptotic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0051930///regulation of sensory perception of pain+++GO:1903999///negative regulation of eating behavior+++GO:1904058///positive regulation of sensory perception of pain+++GO:2000986///negative regulation of behavioral fear response+++GO:2000987///positive regulation of behavioral fear response 12426 12426 'Cckbr' mRNA 1 2 0 0.02 0.04 0 0.02 0 0 0.02 0.006666667 1 0 0 1 0.333333333 0.736910561 -1.456094215 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04971///Gastric acid secretion GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004951///cholecystokinin receptor activity+++GO:0005515///protein binding+++GO:0015054///gastrin receptor activity+++GO:0017046///peptide hormone binding+++GO:0031741///type B gastrin/cholecystokinin receptor binding "GO:0001696///gastric acid secretion+++GO:0001821///histamine secretion+++GO:0002209///behavioral defense response+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0038188///cholecystokinin signaling pathway+++GO:0044849///estrous cycle+++GO:0045851///pH reduction+++GO:0048565///digestive tract development+++GO:0048732///gland development+++GO:0050806///positive regulation of synaptic transmission+++GO:0051930///regulation of sensory perception of pain+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070371///ERK1 and ERK2 cascade+++GO:0090274///positive regulation of somatostatin secretion+++GO:2000987///positive regulation of behavioral fear response" 12428 12428 'Ccna2' mRNA 37.96 30.84 59.8 0.61 0.49 1.02 9.42 8.16 10.55 0.706666667 9.376666667 671.44 567.88 728.55 42.86666667 655.9566667 1.95E-82 3.94417997 04110///Cell cycle+++04152///AMPK signaling pathway+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++05161///Hepatitis B+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05221///Acute myeloid leukemia GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0097124///cyclin A2-CDK2 complex GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0008201///heparin binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019838///growth factor binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0050840///extracellular matrix binding "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001649///osteoblast differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002041///intussusceptive angiogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003278///apoptotic process involved in heart morphogenesis+++GO:0003281///ventricular septum development+++GO:0006275///regulation of DNA replication+++GO:0006935///chemotaxis+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0010518///positive regulation of phospholipase activity+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0016572///histone phosphorylation+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031100///animal organ regeneration+++GO:0032355///response to estradiol+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0033762///response to glucagon+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044319///wound healing, spreading of cells+++GO:0044320///cellular response to leptin stimulus+++GO:0044772///mitotic cell cycle phase transition+++GO:0044843///cell cycle G1/S phase transition+++GO:0045597///positive regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051301///cell division+++GO:0060413///atrial septum morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060591///chondroblast differentiation+++GO:0060710///chorio-allantoic fusion+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061036///positive regulation of cartilage development+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0071314///cellular response to cocaine+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0071732///cellular response to nitric oxide+++GO:0072593///reactive oxygen species metabolic process+++GO:0090102///cochlea development+++GO:0098609///cell-cell adhesion+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2000304///positive regulation of ceramide biosynthetic process" 12442 12442 'Ccnb2' mRNA 10 11 11 0.38 0.41 0.45 13.73 14.72 13.61 0.413333333 14.02 413 432 396 10.66666667 413.6666667 2.07E-68 5.266668001 04068///FoxO signaling pathway+++04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection+++05170///Human immunodeficiency virus 1 infection GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001701///in utero embryonic development+++GO:0007049///cell cycle+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0008315///G2/MI transition of meiotic cell cycle+++GO:0040008///regulation of growth+++GO:0043029///T cell homeostasis+++GO:0044772///mitotic cell cycle phase transition+++GO:0048538///thymus development+++GO:0051301///cell division 12443 12443 'Ccnd1' mRNA 429.94 422.83 421.5 6.3 6.09 6.53 30.7 29.12 32.27 6.306666667 30.69666667 2416.13 2239.82 2460.76 424.7566667 2372.236667 7.51E-190 2.47153428 01522///Endocrine resistance+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04371///Apelin signaling pathway+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04530///Tight junction+++04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05416///Viral myocarditis GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0017053///transcriptional repressor complex+++GO:0031965///nuclear membrane GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding+++GO:0070064///proline-rich region binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000320///re-entry into mitotic cell cycle+++GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010039///response to iron ion+++GO:0010165///response to X-ray+++GO:0010243///response to organonitrogen compound+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0016055///Wnt signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031100///animal organ regeneration+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032026///response to magnesium ion+++GO:0032355///response to estradiol+++GO:0033197///response to vitamin E+++GO:0033327///Leydig cell differentiation+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0044321///response to leptin+++GO:0044772///mitotic cell cycle phase transition+++GO:0045444///fat cell differentiation+++GO:0045471///response to ethanol+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048545///response to steroid hormone+++GO:0051301///cell division+++GO:0051384///response to glucocorticoid+++GO:0051412///response to corticosterone+++GO:0051592///response to calcium ion+++GO:0051726///regulation of cell cycle+++GO:0060749///mammary gland alveolus development+++GO:0070141///response to UV-A+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071310///cellular response to organic substance+++GO:0097421///liver regeneration+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 12444 12444 'Ccnd2' mRNA 4560 4627 4407 41.14 41.17 42.26 21.91 22.57 21.56 41.52333333 22.01333333 2797 2799 2657 4531.333333 2751 8.34E-35 -0.731552013 04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway+++05162///Measles+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0097129///cyclin D2-CDK4 complex GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0007616///long-term memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0043066///negative regulation of apoptotic process+++GO:0044772///mitotic cell cycle phase transition+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0071481///cellular response to X-ray+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 12445 12445 'Ccnd3' mRNA 4112.56 4251.36 4180.76 122.26 124.73 131.15 162.44 164.11 164.84 126.0466667 163.7966667 6313.93 6222.55 6204.77 4181.56 6247.083333 1.47E-22 0.566633388 04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04630///JAK-STAT signaling pathway+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0030213///hyaluronan biosynthetic process+++GO:0042098///T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0044772///mitotic cell cycle phase transition+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 12447 12447 'Ccne1' mRNA 14 17 10 0.41 0.49 0.31 6.12 5.72 5.38 0.403333333 5.74 241 220 205 13.66666667 222 8.98E-39 4.012874896 04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04391///Hippo signaling pathway - fly+++04934///Cushing syndrome+++05161///Hepatitis B+++05162///Measles+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++05222///Small cell lung cancer+++05226///Gastric cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0097134///cyclin E1-CDK2 complex GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000723///telomere maintenance+++GO:0006270///DNA replication initiation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0016055///Wnt signaling pathway+++GO:0032880///regulation of protein localization+++GO:0044772///mitotic cell cycle phase transition+++GO:0045597///positive regulation of cell differentiation+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:1903827///regulation of cellular protein localization 12448 12448 'Ccne2' mRNA 35.42 14.54 29.32 0.64 0.26 0.56 2.5 3.05 1.89 0.486666667 2.48 151.34 178.69 111.78 26.42666667 147.27 2.81E-13 2.480515364 04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04391///Hippo signaling pathway - fly+++04934///Cushing syndrome+++05161///Hepatitis B+++05162///Measles+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++05222///Small cell lung cancer+++05226///Gastric cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0097134///cyclin E1-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000723///telomere maintenance+++GO:0006270///DNA replication initiation+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0032880///regulation of protein localization+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:1903827///regulation of cellular protein localization 12449 12449 'Ccnf' mRNA 33 32 22 0.58 0.55 0.41 5.82 5.26 4.35 0.513333333 5.143333333 381 336 276 29 331 3.97E-48 3.503355752 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030054///cell junction GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000320///re-entry into mitotic cell cycle+++GO:0001890///placenta development+++GO:0007049///cell cycle+++GO:0010826///negative regulation of centrosome duplication+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle 12450 12450 'Ccng1' mRNA 1922 2008 1976 29.98 30.82 32.7 48.04 43.91 45.63 31.16666667 45.86 3544 3164 3260 1968.666667 3322.666667 2.42E-27 0.74162938 04115///p53 signaling pathway+++05206///MicroRNAs in cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006949///syncytium formation+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0043066///negative regulation of apoptotic process+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle 12452 12452 'Ccng2' mRNA 517 566 292 11.55 12.45 6.92 6.43 6.15 6.46 10.30666667 6.346666667 331 309 322 458.3333333 320.6666667 0.007168448 -0.514666022 04068///FoxO signaling pathway+++04115///p53 signaling pathway GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007049///cell cycle+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle 12453 12453 'Ccni' mRNA 1682 1724 1499 34.17 34.7 32.3 31.63 26.36 29.44 33.72333333 29.14333333 1780 1448 1604 1635 1610.666667 0.774258369 -0.032873834 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0044772///mitotic cell cycle phase transition+++GO:0051726///regulation of cell cycle 12454 12454 'Ccnk' mRNA 288.29 223.24 427.39 4.52 3.46 7.17 3.01 2.98 2.42 5.05 2.803333333 220.14 213.91 172.53 312.9733333 202.1933333 0.006314524 -0.660185098 GO:0002944///cyclin K-CDK12 complex+++GO:0002945///cyclin K-CDK13 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008024///cyclin/CDK positive transcription elongation factor complex GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity "GO:0001701///in utero embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:2000737///negative regulation of stem cell differentiation+++GO:2001165///positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues" 12455 12455 'Ccnt1' mRNA 1466.21 1551 1461 13.77 13.02 15.25 11.78 11.59 11.82 14.01333333 11.73 1441 1501 1466 1492.736667 1469.333333 0.751343776 -0.033869252 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0070691///P-TEFb complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0017069///snRNA binding+++GO:0019901///protein kinase binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity+++GO:0070063///RNA polymerase binding+++GO:0097322///7SK snRNA binding "GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:1900364///negative regulation of mRNA polyadenylation" 12457 12457 'Noct' mRNA 128 156 46 2.95 3.52 1.19 6.2 6.68 9.43 2.553333333 7.436666667 295 315 444 110 351.3333333 0.001315224 1.687952127 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0000175///3'-5'-exoribonuclease activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003824///catalytic activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0016787///hydrolase activity+++GO:0019178///NADP phosphatase activity+++GO:0019957///C-C chemokine binding+++GO:0046872///metal ion binding+++GO:0102757///NADPH phosphatase activity "GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0001764///neuron migration+++GO:0002507///tolerance induction+++GO:0006739///NADP metabolic process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007623///circadian rhythm+++GO:0009314///response to radiation+++GO:0009617///response to bacterium+++GO:0009991///response to extracellular stimulus+++GO:0010629///negative regulation of gene expression+++GO:0016311///dephosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0032496///response to lipopolysaccharide+++GO:0032922///circadian regulation of gene expression+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0042752///regulation of circadian rhythm+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045995///regulation of embryonic development+++GO:0046677///response to antibiotic+++GO:0048255///mRNA stabilization+++GO:0048511///rhythmic process+++GO:0048872///homeostasis of number of cells+++GO:0050927///positive regulation of positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 12458 12458 'Ccr6' mRNA 6 13 7 0.3 0.54 0.33 0.17 0.27 0.31 0.39 0.25 4 7 8 8.666666667 6.333333333 0.706410296 -0.452377731 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036126///sperm flagellum+++GO:0097225///sperm midpiece+++GO:0097228///sperm principal piece+++GO:0097524///sperm plasma membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010634///positive regulation of epithelial cell migration+++GO:0019722///calcium-mediated signaling+++GO:0048290///isotype switching to IgA isotypes+++GO:0060326///cell chemotaxis+++GO:0060474///positive regulation of flagellated sperm motility involved in capacitation+++GO:0070098///chemokine-mediated signaling pathway+++GO:0072676///lymphocyte migration+++GO:0072678///T cell migration+++GO:0072679///thymocyte migration+++GO:1904155///DN2 thymocyte differentiation+++GO:1904156///DN3 thymocyte differentiation+++GO:2000319///regulation of T-helper 17 cell differentiation+++GO:2000404///regulation of T cell migration+++GO:2000510///positive regulation of dendritic cell chemotaxis 12460 12460 'Ccs' mRNA 1518 1564 1499 90.62 92.29 94.95 72.71 81.1 71.25 92.62 75.02 1397 1519 1323 1527 1413 0.202871686 -0.123081322 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space GO:0004784///superoxide dismutase activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0006801///superoxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0051353///positive regulation of oxidoreductase activity 12461 12461 'Cct2' mRNA 1979 1948 1883 56 54.38 56.54 72.27 68.67 70.82 55.64 70.58666667 2934 2720 2781 1936.666667 2811.666667 5.85E-16 0.525686657 GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0050821///protein stabilization+++GO:0051086///chaperone mediated protein folding independent of cofactor+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051973///positive regulation of telomerase activity+++GO:0090666///scaRNA localization to Cajal body+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body 12462 12462 'Cct3' mRNA 4102 4288 4268 119.63 123.21 132.04 118.52 122.11 120.72 124.96 120.45 4672 4699 4606 4219.333333 4659 0.060078645 0.13021311 GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005832///chaperonin-containing T-complex+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0046931///pore complex assembly+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere 12464 12464 'Cct4' mRNA 2510 2819 2765 72.83 80.58 85.11 87.43 87.02 84.41 79.50666667 86.28666667 3464 3366 3237 2698 3355.666667 6.86E-05 0.301277126 GO:0002199///zona pellucida receptor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:0090666///scaRNA localization to Cajal body+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body 12465 12465 'Cct5' mRNA 3546 3791 3610 107.21 112.94 115.78 140.7 141.04 139.84 111.9766667 140.5266667 5350 5235 5146 3649 5243.666667 6.26E-18 0.510945458 GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005832///chaperonin-containing T-complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0031681///G-protein beta-subunit binding+++GO:0044183///protein binding involved in protein folding+++GO:0048027///mRNA 5'-UTR binding+++GO:0048487///beta-tubulin binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0009615///response to virus+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere 12466 12466 'Cct6a' mRNA 4356 4502 4448 106.21 108.09 115.05 96.81 98.62 96.23 109.7833333 97.22 4566 4542 4394 4435.333333 4500.666667 0.919523873 0.008445343 GO:0001669///acrosomal vesicle+++GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex+++GO:0005874///microtubule+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0071987///WD40-repeat domain binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere 12467 12467 'Cct6b' mRNA 29 27 37 0.99 0.82 1.21 0.54 0.62 0.46 1.006666667 0.54 19 21 16 31 18.66666667 0.170944603 -0.750089278 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:1901998///toxin transport 12468 12468 'Cct7' mRNA 7036.17 7599.79 7092.98 160.15 170.3 171.25 126.84 129.68 128.28 167.2333333 128.2666667 6409.75 6398.98 6275.97 7242.98 6361.566667 6.35E-04 -0.198853362 GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005832///chaperonin-containing T-complex+++GO:0005874///microtubule+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere 12469 12469 'Cct8' mRNA 4020.11 4066.49 3908.05 94.04 93.67 96.98 95.93 99.42 96.38 94.89666667 97.24333333 4716.24 4772.64 4587.48 3998.216667 4692.12 2.88E-04 0.219238106 GO:0002199///zona pellucida receptor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0044297///cell body+++GO:0045111///intermediate filament cytoskeleton GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0046931///pore complex assembly+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere 12475 12475 'Cd14' mRNA 309 368 377 10.83 12.72 14.02 102.34 103.64 106.49 12.52333333 104.1566667 3354 3315 3377 351.3333333 3348.666667 3.18E-287 3.239437445 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04145///Phagosome+++04620///Toll-like receptor signaling pathway+++04640///Hematopoietic cell lineage+++04936///Alcoholic liver disease+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05146///Amoebiasis+++05152///Tuberculosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft+++GO:0046696///lipopolysaccharide receptor complex GO:0001530///lipopolysaccharide binding+++GO:0070891///lipoteichoic acid binding+++GO:0071723///lipopeptide binding GO:0001819///positive regulation of cytokine production+++GO:0002237///response to molecule of bacterial origin+++GO:0002376///immune system process+++GO:0006898///receptor-mediated endocytosis+++GO:0006954///inflammatory response+++GO:0009408///response to heat+++GO:0009617///response to bacterium+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032026///response to magnesium ion+++GO:0032481///positive regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034612///response to tumor necrosis factor+++GO:0045087///innate immune response+++GO:0045471///response to ethanol+++GO:0045807///positive regulation of endocytosis+++GO:0051602///response to electrical stimulus+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071726///cellular response to diacyl bacterial lipopeptide+++GO:0071727///cellular response to triacyl bacterial lipopeptide+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 12476 12476 'Cd151' mRNA 726 710 651 22.94 22.52 21.88 31.83 28.22 29.01 22.44666667 29.68666667 1152 984 1015 695.6666667 1050.333333 9.00E-10 0.582638492 GO:0005604///basement membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding+++GO:0005515///protein binding "GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0042098///T cell proliferation+++GO:0044319///wound healing, spreading of cells+++GO:0045807///positive regulation of endocytosis" 12477 12477 'Ctla4' mRNA 0 1 0 0 0.03 0 0.08 0.03 0.03 0.01 0.046666667 3 1 1 0.333333333 1.666666667 0.479203414 2.194789667 04514///Cell adhesion molecules+++04660///T cell receptor signaling pathway+++05320///Autoimmune thyroid disease+++05323///Rheumatoid arthritis GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098636///protein complex involved in cell adhesion GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030889///negative regulation of B cell proliferation+++GO:0042129///regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0050777///negative regulation of immune response+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway 12478 12478 'Cd19' mRNA 0 6 0 0 0.1 0 0 0.06 0 0.033333333 0.02 0 3 0 2 1 0.787481284 -0.94607854 04151///PI3K-Akt signaling pathway+++04640///Hematopoietic cell lineage+++04662///B cell receptor signaling pathway+++05169///Epstein-Barr virus infection+++05340///Primary immunodeficiency GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0001923///B-1 B cell differentiation+++GO:0002250///adaptive immune response+++GO:0002322///B cell proliferation involved in immune response+++GO:0002376///immune system process+++GO:0016064///immunoglobulin mediated immune response+++GO:0019724///B cell mediated immunity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0050864///regulation of B cell activation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol 12479 12479 'Cd1d1' mRNA 304 261 298 9.66 8.1 9.9 8.8 7.63 8.46 9.22 8.296666667 319 274 301 287.6666667 298 0.863090843 0.035893873 04530///Tight junction+++04640///Hematopoietic cell lineage+++05146///Amoebiasis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030882///lipid antigen binding+++GO:0030883///endogenous lipid antigen binding+++GO:0030884///exogenous lipid antigen binding+++GO:0042393///histone binding+++GO:0042608///T cell receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0071723///lipopeptide binding "GO:0001865///NK T cell differentiation+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033084///regulation of immature T cell proliferation in thymus+++GO:0042102///positive regulation of T cell proliferation+++GO:0043032///positive regulation of macrophage activation+++GO:0045059///positive thymic T cell selection+++GO:0045087///innate immune response+++GO:0048006///antigen processing and presentation, endogenous lipid antigen via MHC class Ib+++GO:0048007///antigen processing and presentation, exogenous lipid antigen via MHC class Ib+++GO:0050776///regulation of immune response+++GO:0051135///positive regulation of NK T cell activation+++GO:0051138///positive regulation of NK T cell differentiation" 12481 12481 'Cd2' mRNA 4 5 0 0.22 0.27 0 1.75 1.21 1.17 0.163333333 1.376666667 37 25 24 3 28.66666667 4.14E-05 3.257339037 04514///Cell adhesion molecules+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association GO:0007155///cell adhesion+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034113///heterotypic cell-cell adhesion+++GO:0042110///T cell activation+++GO:0098609///cell-cell adhesion 12482 12482 'Ms4a1' mRNA 0 6 2 0 0.11 0.04 0.02 0 0.05 0.05 0.023333333 1 0 3 2.666666667 1.333333333 0.700078568 -0.999187596 04640///Hematopoietic cell lineage GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0005154///epidermal growth factor receptor binding+++GO:0019865///immunoglobulin binding+++GO:0042802///identical protein binding GO:0002115///store-operated calcium entry+++GO:0009617///response to bacterium+++GO:0030183///B cell differentiation+++GO:0042113///B cell activation+++GO:0050853///B cell receptor signaling pathway+++GO:0051262///protein tetramerization+++GO:1902656///calcium ion import into cytosol 12483 12483 'Cd22' mRNA 14 9 22 0.21 0.13 0.34 3.14 3.07 3.17 0.226666667 3.126666667 246 235 241 15 240.6666667 1.18E-39 3.986424255 04514///Cell adhesion molecules+++04640///Hematopoietic cell lineage+++04662///B cell receptor signaling pathway GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032809///neuronal cell body membrane+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0042609///CD4 receptor binding GO:0002638///negative regulation of immunoglobulin production+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0030100///regulation of endocytosis+++GO:0030888///regulation of B cell proliferation+++GO:0042113///B cell activation+++GO:0050776///regulation of immune response+++GO:0050849///negative regulation of calcium-mediated signaling+++GO:0050859///negative regulation of B cell receptor signaling pathway 12484 12484 'Cd24a' mRNA 3224 3121 2834 101.52 96.86 94.98 74.64 70.31 73.25 97.78666667 72.73333333 2717 2502 2587 3059.666667 2602 1.52E-04 -0.24441861 04640///Hematopoietic cell lineage GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0031528///microvillus membrane+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0060170///ciliary membrane+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0030544///Hsp70 protein binding+++GO:0051879///Hsp90 protein binding GO:0001666///response to hypoxia+++GO:0001775///cell activation+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002237///response to molecule of bacterial origin+++GO:0002329///pre-B cell differentiation+++GO:0002376///immune system process+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002842///positive regulation of T cell mediated immune response to tumor cell+++GO:0002863///positive regulation of inflammatory response to antigenic stimulus+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007274///neuromuscular synaptic transmission+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0008637///apoptotic mitochondrial changes+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0022407///regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030262///apoptotic nuclear changes+++GO:0030889///negative regulation of B cell proliferation+++GO:0031175///neuron projection development+++GO:0031295///T cell costimulation+++GO:0032597///B cell receptor transport into membrane raft+++GO:0032600///chemokine receptor transport out of membrane raft+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032913///negative regulation of transforming growth factor beta3 production+++GO:0033625///positive regulation of integrin activation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0034107///negative regulation of erythrocyte clearance+++GO:0034109///homotypic cell-cell adhesion+++GO:0034119///negative regulation of erythrocyte aggregation+++GO:0042103///positive regulation of T cell homeostatic proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042325///regulation of phosphorylation+++GO:0042632///cholesterol homeostasis+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043408///regulation of MAPK cascade+++GO:0043627///response to estrogen+++GO:0045087///innate immune response+++GO:0045577///regulation of B cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045730///respiratory burst+++GO:0046014///negative regulation of T cell homeostatic proliferation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0048488///synaptic vesicle endocytosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050768///negative regulation of neurogenesis+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:0097190///apoptotic signaling pathway+++GO:0106015///negative regulation of inflammatory response to wounding+++GO:0106016///positive regulation of inflammatory response to wounding+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation 12487 12487 'Cd28' mRNA 9 4 8 0.11 0.05 0.11 1.49 1.62 1.3 0.09 1.47 138 146 116 7 133.3333333 8.57E-24 4.238528234 04514///Cell adhesion molecules+++04660///T cell receptor signaling pathway+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05162///Measles+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05320///Autoimmune thyroid disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0098636///protein complex involved in cell adhesion GO:0002020///protease binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding GO:0002863///positive regulation of inflammatory response to antigenic stimulus+++GO:0006955///immune response+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0031295///T cell costimulation+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0042129///regulation of T cell proliferation+++GO:0045060///negative thymic T cell selection+++GO:0045066///regulatory T cell differentiation+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0050852///T cell receptor signaling pathway+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0097190///apoptotic signaling pathway 12488 12488 'Cd2ap' mRNA 1477 1406 1015 14.7 13.64 10.66 11.64 10.6 11.15 13 11.13 1358 1209 1261 1299.333333 1276 0.839303607 -0.031865171 05100///Bacterial invasion of epithelial cells GO:0001650///fibrillar center+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0016050///vesicle organization+++GO:0016477///cell migration+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048259///regulation of receptor-mediated endocytosis+++GO:0050714///positive regulation of protein secretion+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0051301///cell division+++GO:0098609///cell-cell adhesion+++GO:1900182///positive regulation of protein localization to nucleus+++GO:2000249///regulation of actin cytoskeleton reorganization 12489 12489 'Cd33' mRNA 99 79 58 2.16 1.7 1.37 17.66 14.89 16.65 1.743333333 16.4 917 754 837 78.66666667 836 3.51E-103 3.400858084 04640///Hematopoietic cell lineage GO:0005654///nucleoplasm+++GO:0005777///peroxisome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding GO:0002765///immune response-inhibiting signal transduction+++GO:0007155///cell adhesion+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0050714///positive regulation of protein secretion+++GO:0051926///negative regulation of calcium ion transport+++GO:0098609///cell-cell adhesion+++GO:1903615///positive regulation of protein tyrosine phosphatase activity 12490 12490 'Cd34' mRNA 441 507 485 9.8 11.15 11.42 25.67 24.89 26.56 10.79 25.70666667 1328 1258 1332 477.6666667 1306 3.58E-50 1.438516006 04514///Cell adhesion molecules+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0036053///glomerular endothelium fenestra+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0008134///transcription factor binding+++GO:0030246///carbohydrate binding+++GO:0043199///sulfate binding GO:0001894///tissue homeostasis+++GO:0001935///endothelial cell proliferation+++GO:0003094///glomerular filtration+++GO:0003158///endothelium development+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030195///negative regulation of blood coagulation+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0035759///mesangial cell-matrix adhesion+++GO:0038001///paracrine signaling+++GO:0042482///positive regulation of odontogenesis+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0048870///cell motility+++GO:0050900///leukocyte migration+++GO:0060290///transdifferentiation+++GO:0061042///vascular wound healing+++GO:0071425///hematopoietic stem cell proliferation+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0071657///positive regulation of granulocyte colony-stimulating factor production+++GO:0071971///extracellular exosome assembly+++GO:0072011///glomerular endothelium development+++GO:0072089///stem cell proliferation+++GO:0072254///metanephric glomerular mesangial cell differentiation+++GO:0098609///cell-cell adhesion+++GO:1900035///negative regulation of cellular response to heat+++GO:1900038///negative regulation of cellular response to hypoxia+++GO:1900168///positive regulation of glial cell-derived neurotrophic factor secretion+++GO:1901215///negative regulation of neuron death+++GO:2001214///positive regulation of vasculogenesis 12491 12491 'Cd36' mRNA 43 30 41 0.8 0.59 0.81 14.87 14.11 14.54 0.733333333 14.50666667 888 816 850 38 851.3333333 5.25E-140 4.472793098 03320///PPAR signaling pathway+++04145///Phagosome+++04152///AMPK signaling pathway+++04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++04920///Adipocytokine signaling pathway+++04931///Insulin resistance+++04975///Fat digestion and absorption+++04979///Cholesterol metabolism+++05144///Malaria+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0071944///cell periphery GO:0001540///amyloid-beta binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005515///protein binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0015636///short-chain fatty acid transmembrane transporter activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0035325///Toll-like receptor binding+++GO:0044877///protein-containing complex binding+++GO:0050431///transforming growth factor beta binding+++GO:0070053///thrombospondin receptor activity+++GO:0070538///oleic acid binding+++GO:0070892///lipoteichoic acid receptor activity+++GO:0071813///lipoprotein particle binding+++GO:0150025///oxidised low-density lipoprotein particle receptor activity+++GO:1901480///oleate transmembrane transporter activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001676///long-chain fatty acid metabolic process+++GO:0001819///positive regulation of cytokine production+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006631///fatty acid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006898///receptor-mediated endocytosis+++GO:0006910///phagocytosis, recognition+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007263///nitric oxide mediated signal transduction+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010886///positive regulation of cholesterol storage+++GO:0010942///positive regulation of cell death+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0015912///short-chain fatty acid transport+++GO:0016525///negative regulation of angiogenesis+++GO:0019395///fatty acid oxidation+++GO:0019915///lipid storage+++GO:0019934///cGMP-mediated signaling+++GO:0030194///positive regulation of blood coagulation+++GO:0030299///intestinal cholesterol absorption+++GO:0030301///cholesterol transport+++GO:0031623///receptor internalization+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033993///response to lipid+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0034197///triglyceride transport+++GO:0034381///plasma lipoprotein particle clearance+++GO:0034383///low-density lipoprotein particle clearance+++GO:0035634///response to stilbenoid+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042593///glucose homeostasis+++GO:0042755///eating behavior+++GO:0042953///lipoprotein transport+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0043277///apoptotic cell clearance+++GO:0043410///positive regulation of MAPK cascade+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0044539///long-chain fatty acid import+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050766///positive regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050892///intestinal absorption+++GO:0050909///sensory perception of taste+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070508///cholesterol import+++GO:0070542///response to fatty acid+++GO:0070543///response to linoleic acid+++GO:0071221///cellular response to bacterial lipopeptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071447///cellular response to hydroperoxide+++GO:0071726///cellular response to diacyl bacterial lipopeptide+++GO:0090208///positive regulation of triglyceride metabolic process+++GO:0097009///energy homeostasis+++GO:0098900///regulation of action potential+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0150024///oxidised low-density lipoprotein particle clearance+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904646///cellular response to amyloid-beta+++GO:1990000///amyloid fibril formation+++GO:1990379///lipid transport across blood brain barrier+++GO:2000121///regulation of removal of superoxide radicals+++GO:2000334///positive regulation of blood microparticle formation+++GO:2000379///positive regulation of reactive oxygen species metabolic process" 12492 12492 'Scarb2' mRNA 1604 1559 1366 18.2 17.39 16.44 27.21 25.38 26.68 17.34333333 26.42333333 2761 2516 2623 1509.666667 2633.333333 2.25E-30 0.792577657 04142///Lysosome GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030666///endocytic vesicle membrane+++GO:0043202///lysosomal lumen GO:0001786///phosphatidylserine binding+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0019899///enzyme binding+++GO:0031210///phosphatidylcholine binding+++GO:0038024///cargo receptor activity+++GO:0042803///protein homodimerization activity+++GO:0051087///chaperone binding GO:0006622///protein targeting to lysosome+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007605///sensory perception of sound+++GO:0010467///gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0015917///aminophospholipid transport+++GO:0043471///regulation of cellular carbohydrate catabolic process+++GO:1905123///regulation of glucosylceramidase activity 12493 12493 'Cd37' mRNA 31 38 26 1.29 1.64 1.19 27.43 25.79 23.79 1.373333333 25.67 681 634 584 31.66666667 633 4.94E-105 4.311337009 04640///Hematopoietic cell lineage GO:0001772///immunological synapse+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002639///positive regulation of immunoglobulin production+++GO:0002920///regulation of humoral immune response+++GO:0008285///negative regulation of cell proliferation+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0042832///defense response to protozoan+++GO:0050688///regulation of defense response to virus 12494 12494 'Cd38' mRNA 558 612 593 10.17 10.98 11.46 37.84 35.6 35.27 10.87 36.23666667 2389 2195.01 2156 587.6666667 2246.67 3.02E-118 1.921753034 00760///Nicotinate and nicotinamide metabolism+++04020///Calcium signaling pathway+++04640///Hematopoietic cell lineage+++04921///Oxytocin signaling pathway+++04970///Salivary secretion+++04972///Pancreatic secretion GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030667///secretory granule membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003953///NAD+ nucleosidase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0042802///identical protein binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" "GO:0001666///response to hypoxia+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0010977///negative regulation of neuron projection development+++GO:0014824///artery smooth muscle contraction+++GO:0030307///positive regulation of cell growth+++GO:0030890///positive regulation of B cell proliferation+++GO:0032024///positive regulation of insulin secretion+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032570///response to progesterone+++GO:0033194///response to hydroperoxide+++GO:0034097///response to cytokine+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0045779///negative regulation of bone resorption+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0050853///B cell receptor signaling pathway+++GO:0060292///long-term synaptic depression+++GO:0070555///response to interleukin-1" 12495 12495 'Entpd1' mRNA 342 427 400 4.52 5.44 5.49 11.92 11.75 11.3 5.15 11.65666667 1046 1012 962 389.6666667 1006.666667 7.09E-34 1.356504252 00230///Purine metabolism+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection GO:0005575///cellular_component+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097060///synaptic membrane GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0004382///guanosine-diphosphatase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0042802///identical protein binding+++GO:0043262///adenosine-diphosphatase activity+++GO:0045134///uridine-diphosphatase activity+++GO:0102485///dATP phosphohydrolase activity+++GO:0102486///dCTP phosphohydrolase activity+++GO:0102487///dUTP phosphohydrolase activity+++GO:0102488///dTTP phosphohydrolase activity+++GO:0102489///GTP phosphohydrolase activity+++GO:0102490///8-oxo-dGTP phosphohydrolase activity+++GO:0102491///dGTP phosphohydrolase activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0009181///purine ribonucleoside diphosphate catabolic process+++GO:0030168///platelet activation+++GO:0033602///negative regulation of dopamine secretion+++GO:0046032///ADP catabolic process+++GO:2001170///negative regulation of ATP biosynthetic process 12496 12496 'Entpd2' mRNA 274 257 235 8.08 7.47 7.35 8.8 8.31 8.4 7.633333333 8.503333333 343 316 317 255.3333333 325.3333333 0.029381993 0.33884464 00230///Purine metabolism+++04742///Taste transduction GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031253///cell projection membrane+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0042802///identical protein binding+++GO:0043262///adenosine-diphosphatase activity+++GO:0045134///uridine-diphosphatase activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0009181///purine ribonucleoside diphosphate catabolic process+++GO:0030168///platelet activation+++GO:0071354///cellular response to interleukin-6 12497 12497 'Entpd6' mRNA 1036 1102 1163 21.84 22.6 25.81 12.39 11.3 11.39 23.41666667 11.69333333 671 601 609 1100.333333 627 1.03E-15 -0.82670214 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005524///ATP binding+++GO:0008894///guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0036384///cytidine diphosphatase activity+++GO:0045134///uridine-diphosphatase activity+++GO:1990003///IDP phosphatase activity" GO:0009134///nucleoside diphosphate catabolic process+++GO:0016311///dephosphorylation+++GO:0032026///response to magnesium ion+++GO:0051592///response to calcium ion 12499 12499 'Entpd5' mRNA 809 792 866 8.69 8.34 9.89 7.33 6.69 6.51 8.973333333 6.843333333 785 699 674 822.3333333 719.3333333 0.077033592 -0.208553136 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0045134///uridine-diphosphatase activity GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0045821///positive regulation of glycolytic process+++GO:0046034///ATP metabolic process+++GO:0051084///'de novo' posttranslational protein folding 12500 12500 'Cd3d' mRNA 7 5 3 0.32 0.22 0.14 0.87 0.86 1.31 0.226666667 1.013333333 22 21 32 5 25 0.001200638 2.318244449 04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05142///Chagas disease+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042101///T cell receptor complex+++GO:0042105///alpha-beta T cell receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0042110///T cell activation+++GO:0045059///positive thymic T cell selection+++GO:0065003///protein-containing complex assembly 12501 12501 'Cd3e' mRNA 14 22 8 0.57 0.85 0.35 1.17 0.87 0.88 0.59 0.973333333 33 24 24 14.66666667 27 0.158403066 0.879492059 04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05142///Chagas disease+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency GO:0001772///immunological synapse+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042101///T cell receptor complex+++GO:0042105///alpha-beta T cell receptor complex+++GO:0043197///dendritic spine+++GO:0044297///cell body GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002669///positive regulation of T cell anergy+++GO:0007166///cell surface receptor signaling pathway+++GO:0007584///response to nutrient+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016358///dendrite development+++GO:0021549///cerebellum development+++GO:0031295///T cell costimulation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033077///T cell differentiation in thymus+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0042102///positive regulation of T cell proliferation+++GO:0045059///positive thymic T cell selection+++GO:0045060///negative thymic T cell selection+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0046649///lymphocyte activation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0097190///apoptotic signaling pathway 12502 12502 'Cd3g' mRNA 7 8 16 0.44 0.49 1.06 2.17 2 1.63 0.663333333 1.933333333 40 36 29 10.33333333 35 0.002670621 1.733627846 04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05142///Chagas disease+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042105///alpha-beta T cell receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007166///cell surface receptor signaling pathway+++GO:0015031///protein transport+++GO:0045059///positive thymic T cell selection+++GO:0070228///regulation of lymphocyte apoptotic process 12503 12503 'Cd247' mRNA 2 6 12 0.07 0.14 0.23 0.42 0.4 0.47 0.146666667 0.43 20 16 15 6.666666667 17 0.122486759 1.316169176 04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05142///Chagas disease+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042101///T cell receptor complex+++GO:0042105///alpha-beta T cell receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:1990782///protein tyrosine kinase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0032623///interleukin-2 production+++GO:0050852///T cell receptor signaling pathway+++GO:0065003///protein-containing complex assembly+++GO:2000010///positive regulation of protein localization to cell surface 12504 12504 'Cd4' mRNA 40 31 35 0.71 0.54 0.66 2.32 1.41 2.01 0.636666667 1.913333333 150 89 123 35.33333333 120.6666667 1.71E-08 1.755396226 04060///Cytokine-cytokine receptor interaction+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05135///Yersinia infection+++05166///Human T-cell leukemia virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0015026///coreceptor activity+++GO:0019865///immunoglobulin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0023026///MHC class II protein complex binding+++GO:0042011///interleukin-16 binding+++GO:0042012///interleukin-16 receptor activity+++GO:0042289///MHC class II protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:1990782///protein tyrosine kinase binding "GO:0001816///cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006948///induction by virus of host cell-cell fusion+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0030217///T cell differentiation+++GO:0030225///macrophage differentiation+++GO:0032507///maintenance of protein location in cell+++GO:0033674///positive regulation of kinase activity+++GO:0035397///helper T cell enhancement of adaptive immune response+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0045058///T cell selection+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046598///positive regulation of viral entry into host cell+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050863///regulation of T cell activation+++GO:0050870///positive regulation of T cell activation+++GO:0051924///regulation of calcium ion transport+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus" 12505 12505 'Cd44' mRNA 345 383 350 4.09 4.46 4.35 23.66 20.64 24.58 4.3 22.96 2257 1929 2282 359.3333333 2156 2.08E-163 2.572798514 04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++05131///Shigellosis+++05169///Epstein-Barr virus infection+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0032991///protein-containing complex+++GO:0035692///macrophage migration inhibitory factor receptor complex+++GO:0042995///cell projection GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005540///hyaluronic acid binding+++GO:0019901///protein kinase binding+++GO:0019955///cytokine binding+++GO:0051219///phosphoprotein binding "GO:0001558///regulation of cell growth+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0002246///wound healing involved in inflammatory response+++GO:0002821///positive regulation of adaptive immune response+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030214///hyaluronan catabolic process+++GO:0031175///neuron projection development+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034238///macrophage fusion+++GO:0042110///T cell activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0044319///wound healing, spreading of cells+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051216///cartilage development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070487///monocyte aggregation+++GO:1900625///positive regulation of monocyte aggregation+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation" 12506 12506 'Cd48' mRNA 68 73 67 3.5 3.67 3.62 64.09 58.72 59.26 3.596666667 60.69 1436 1280 1281 69.33333333 1332.333333 5.40E-210 4.252464352 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0003823///antigen binding+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0002819///regulation of adaptive immune response+++GO:0007165///signal transduction+++GO:0042110///T cell activation+++GO:0045576///mast cell activation 12507 12507 'Cd5' mRNA 1 5 7 0.03 0.14 0.2 0.5 0.54 0.35 0.123333333 0.463333333 21 22 14 4.333333333 19 0.012475052 2.108411605 04640///Hematopoietic cell lineage GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044214///spanning component of plasma membrane GO:0005044///scavenger receptor activity+++GO:0005515///protein binding GO:0006897///endocytosis+++GO:0031295///T cell costimulation+++GO:0097190///apoptotic signaling pathway 12508 12508 'Cd53' mRNA 289 262 302 5.69 5.08 6.31 97.63 91.34 95.63 5.693333333 94.86666667 5701 5209 5407 284.3333333 5439 0 4.244016955 GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0042802///identical protein binding GO:0045661///regulation of myoblast differentiation+++GO:0098609///cell-cell adhesion+++GO:1901741///positive regulation of myoblast fusion 12509 12509 'Cd59a' mRNA 2672.33 2785.42 2800.82 87.87 89.78 97.18 77.12 84.01 75.82 91.61 78.98333333 2712.52 2866.77 2573.47 2752.856667 2717.586667 0.764293535 -0.031314815 04610///Complement and coagulation cascades+++04640///Hematopoietic cell lineage GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0042383///sarcolemma+++GO:0043218///compact myelin GO:0001848///complement binding GO:0001971///negative regulation of activation of membrane attack complex+++GO:0016525///negative regulation of angiogenesis+++GO:0030449///regulation of complement activation+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045916///negative regulation of complement activation+++GO:0090272///negative regulation of fibroblast growth factor production+++GO:1903659///regulation of complement-dependent cytotoxicity+++GO:1903660///negative regulation of complement-dependent cytotoxicity 12511 12511 'Cd6' mRNA 4 3 1 0.08 0.06 0.02 0.54 0.27 0.48 0.053333333 0.43 34 16 26 2.666666667 25.33333333 9.62E-05 3.239626268 04514///Cell adhesion molecules GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0042101///T cell receptor complex+++GO:0044214///spanning component of plasma membrane GO:0001530///lipopolysaccharide binding+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0070891///lipoteichoic acid binding GO:0001771///immunological synapse formation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0006897///endocytosis+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0042102///positive regulation of T cell proliferation+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 12512 12512 'Cd63' mRNA 7044 7361 7115 512.17 529.81 548.85 1525.82 1591.11 1490.37 530.2766667 1535.766667 24045 24430 22686 7173.333333 23720.33333 1.34E-211 1.713321072 04142///Lysosome+++05205///Proteoglycans in cancer "GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031902///late endosome membrane+++GO:0031904///endosome lumen+++GO:0032585///multivesicular body membrane+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0097487///multivesicular body, internal vesicle" GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0002092///positive regulation of receptor internalization+++GO:0007160///cell-matrix adhesion+++GO:0010633///negative regulation of epithelial cell migration+++GO:0015031///protein transport+++GO:0016477///cell migration+++GO:0030855///epithelial cell differentiation+++GO:0034613///cellular protein localization+++GO:0035646///endosome to melanosome transport+++GO:0043473///pigmentation+++GO:0045785///positive regulation of cell adhesion+++GO:0045807///positive regulation of endocytosis+++GO:0048757///pigment granule maturation+++GO:0050931///pigment cell differentiation+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:2001046///positive regulation of integrin-mediated signaling pathway 12514 12514 'Cd68' mRNA 245 232 226 11.98 11.2 11.72 425.33 417.65 416.49 11.63333333 419.8233333 9986 9564 9456 234.3333333 9668.666667 0 5.355456254 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane GO:0002437///inflammatory response to antigenic stimulus+++GO:0002605///negative regulation of dendritic cell antigen processing and presentation+++GO:0007568///aging+++GO:0031669///cellular response to nutrient levels+++GO:0035425///autocrine signaling+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071310///cellular response to organic substance+++GO:0072594///establishment of protein localization to organelle+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus 12515 12515 'Cd69' mRNA 5 3 4 0.18 0.11 0.15 2.46 2.71 2.46 0.146666667 2.543333333 81 86 78 4 81.66666667 1.37E-15 4.340716891 GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005509///calcium ion binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding GO:0035690///cellular response to drug 12516 12516 'Cd7' mRNA 1 3 1 0.06 0.18 0.06 0.53 0.54 0.82 0.1 0.63 10 10 15 1.666666667 11.66666667 0.014119536 2.805521598 04640///Hematopoietic cell lineage GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0048873///homeostasis of number of cells within a tissue 12517 12517 'Cd72' mRNA 88.92 103.98 104.08 3.56 4.02 4.51 26.82 30.43 27.4 4.03 28.21666667 767.92 844.72 759.51 98.99333333 790.7166667 2.78E-94 2.994488378 04662///B cell receptor signaling pathway GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0030246///carbohydrate binding 12518 12518 'Cd79a' mRNA 272 244 239 17.35 15.39 16.17 11.07 11.24 9.61 16.30333333 10.64 199 197 167 251.6666667 187.6666667 0.016261461 -0.434735846 04662///B cell receptor signaling pathway+++05340///Primary immunodeficiency GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019815///B cell receptor complex+++GO:0045121///membrane raft GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation+++GO:0050853///B cell receptor signaling pathway 12519 12519 'Cd80' mRNA 17 13 22 0.32 0.23 0.41 1.18 1.13 1.43 0.32 1.246666667 73 66 77 17.33333333 72 3.29E-07 2.035724087 04514///Cell adhesion molecules+++04620///Toll-like receptor signaling pathway+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05320///Autoimmune thyroid disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098636///protein complex involved in cell adhesion GO:0005515///protein binding+++GO:0015026///coreceptor activity GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0031295///T cell costimulation+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0071222///cellular response to lipopolysaccharide 12520 12520 'Cd81' mRNA 19510.03 19994.07 19964.95 758.1 766.25 823.03 1206.25 1218.48 1193.08 782.46 1205.936667 35660.47 35149.51 34122.79 19823.01667 34977.59 1.64E-52 0.806181371 04662///B cell receptor signaling pathway+++05144///Malaria+++05160///Hepatitis C GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031982///vesicle+++GO:0070062///extracellular exosome+++GO:0097197///tetraspanin-enriched microdomain GO:0001618///virus receptor activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0042289///MHC class II protein binding+++GO:1990459///transferrin receptor binding "GO:0000187///activation of MAPK activity+++GO:0001771///immunological synapse formation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0002863///positive regulation of inflammatory response to antigenic stimulus+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0030307///positive regulation of cell growth+++GO:0030890///positive regulation of B cell proliferation+++GO:0031623///receptor internalization+++GO:0031647///regulation of protein stability+++GO:0034238///macrophage fusion+++GO:0035783///CD4-positive, alpha-beta T cell costimulation+++GO:0042127///regulation of cell proliferation+++GO:0043128///positive regulation of 1-phosphatidylinositol 4-kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046718///viral entry into host cell+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0050871///positive regulation of B cell activation+++GO:0061462///protein localization to lysosome+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0072675///osteoclast fusion+++GO:1903911///positive regulation of receptor clustering+++GO:1904352///positive regulation of protein catabolic process in the vacuole+++GO:1905521///regulation of macrophage migration+++GO:1905676///positive regulation of adaptive immune memory response+++GO:2000145///regulation of cell motility+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2001190///positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell" 12521 12521 'Cd82' mRNA 5078 5067 4504 169.04 166.3 159.04 97.34 98.93 100.54 164.7933333 98.93666667 3362 3364 3369 4883 3365 4.55E-22 -0.54680503 04115///p53 signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 12522 12522 'Cd83' mRNA 112 118 142 2.96 3.07 3.98 17.8 18.19 18.41 3.336666667 18.13333333 775 773 776 124 774.6666667 1.20E-77 2.628491674 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0014070///response to organic cyclic compound+++GO:0032713///negative regulation of interleukin-4 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation" 12523 12523 'Cd84' mRNA 145 131 138 2.45 2.12 2.6 53.4 50.33 51.17 2.39 51.63333333 2669.98 2502 2417.44 138 2529.806667 0 4.183916223 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0007155///cell adhesion+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032685///negative regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032701///negative regulation of interleukin-18 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033004///negative regulation of mast cell activation+++GO:0042110///T cell activation+++GO:0043030///regulation of macrophage activation+++GO:0043305///negative regulation of mast cell degranulation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045087///innate immune response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:2001256///regulation of store-operated calcium entry 12524 12524 'Cd86' mRNA 72 50 49 1.59 1.08 1.14 10.14 8.37 8.44 1.27 8.983333333 532 429 429 57 463.3333333 1.27E-55 3.011287134 04514///Cell adhesion molecules+++04620///Toll-like receptor signaling pathway+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05167///Kaposi sarcoma-associated herpesvirus infection+++05202///Transcriptional misregulation in cancer+++05320///Autoimmune thyroid disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0002224///toll-like receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002668///negative regulation of T cell anergy+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0023035///CD40 signaling pathway+++GO:0031295///T cell costimulation+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042113///B cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0051607///defense response to virus+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1990051///activation of protein kinase C activity 12525 12525 'Cd8a' mRNA 6 5 5 0.1 0.09 0.09 0.34 0.39 0.51 0.093333333 0.413333333 22 25 32 5.333333333 26.33333333 7.66E-04 2.294749808 04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04660///T cell receptor signaling pathway+++05135///Yersinia infection+++05340///Primary immunodeficiency GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0023024///MHC class I protein complex binding+++GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002456///T cell mediated immunity+++GO:0007166///cell surface receptor signaling pathway+++GO:0042110///T cell activation+++GO:0045065///cytotoxic T cell differentiation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0051607///defense response to virus 12526 12526 'Cd8b1' mRNA 9.96 4.7 8.51 0.4 0.19 0.36 1.15 1.02 1.03 0.316666667 1.066666667 33.06 28.58 28.66 7.723333333 30.1 0.001065017 2.065693853 04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04660///T cell receptor signaling pathway+++05135///Yersinia infection+++05340///Primary immunodeficiency GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0042288///MHC class I protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0050776///regulation of immune response 12527 12527 'Cd9' mRNA 22900 23606 22245 1175.56 1196.79 1211.59 976.27 982.76 988.48 1194.646667 982.5033333 21825 21426 21367 22917 21539.33333 0.044784175 -0.101017145 04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome GO:0005178///integrin binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0008347///glial cell migration+++GO:0009414///response to water deprivation+++GO:0014003///oligodendrocyte development+++GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0030913///paranodal junction assembly+++GO:0031623///receptor internalization+++GO:0035036///sperm-egg recognition+++GO:0051271///negative regulation of cellular component movement+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090331///negative regulation of platelet aggregation+++GO:1905521///regulation of macrophage migration 12530 12530 'Cdc25a' mRNA 369 385 367 5.5 5.65 5.8 4.69 4.31 4.61 5.65 4.536666667 363 325 345 373.6666667 344.3333333 0.414110114 -0.130365676 04110///Cell cycle+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0051087///chaperone binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0009314///response to radiation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0034644///cellular response to UV+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0051301///cell division+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:1904056///positive regulation of cholangiocyte proliferation 12531 12531 'Cdc25b' mRNA 995 1006 993 17.82 17.74 18.88 10.12 9.69 10.42 18.14666667 10.07666667 651 607 646 998 634.6666667 2.07E-12 -0.665714109 04010///MAPK signaling pathway+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++05206///MicroRNAs in cancer GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0001556///oocyte maturation+++GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007144///female meiosis I+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition 12532 12532 'Cdc25c' mRNA 0 1 1 0 0.03 0.04 2.01 1.68 1.74 0.023333333 1.81 73 60 64 0.666666667 65.66666667 4.75E-09 6.608798061 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++05170///Human immunodeficiency virus 1 infection+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0016607///nuclear speck+++GO:0048471///perinuclear region of cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0050699///WW domain binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0051301///cell division+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition 12534 12534 'Cdk1' mRNA 25 26 12 0.31 0.32 0.16 7.07 7.39 7.2 0.263333333 7.22 658 672 649 21 659.6666667 3.50E-108 4.965886903 04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04218///Cellular senescence+++04540///Gap junction+++04914///Progesterone-mediated oocyte maturation+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0030496///midbody+++GO:0072686///mitotic spindle+++GO:0097125///cyclin B1-CDK1 complex GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0030544///Hsp70 protein binding+++GO:0035173///histone kinase activity+++GO:0097472///cyclin-dependent protein kinase activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007569///cell aging+++GO:0008283///cell proliferation+++GO:0009636///response to toxic substance+++GO:0010243///response to organonitrogen compound+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0014075///response to amine+++GO:0014823///response to activity+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030261///chromosome condensation+++GO:0031100///animal organ regeneration+++GO:0034501///protein localization to kinetochore+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0044772///mitotic cell cycle phase transition+++GO:0045471///response to ethanol+++GO:0045740///positive regulation of DNA replication+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046686///response to cadmium ion+++GO:0046688///response to copper ion+++GO:0048511///rhythmic process+++GO:0048678///response to axon injury+++GO:0051301///cell division+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0065003///protein-containing complex assembly+++GO:0070301///cellular response to hydrogen peroxide+++GO:0090166///Golgi disassembly+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport 12537 12537 'Cdk11b' mRNA 1398 1310 1380 28.34 26.05 29.61 25.5 26.33 25.04 28 25.62333333 1445 1463 1383 1362.666667 1430.333333 0.603390902 0.056891697 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001824///blastocyst development+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division+++GO:0007346///regulation of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0050684///regulation of mRNA processing+++GO:2001234///negative regulation of apoptotic signaling pathway 12539 12539 'Cdc37' mRNA 3414 3308 3344 124.86 119.3 129.89 136.79 138.25 133.42 124.6833333 136.1533333 4296 4238 4054 3355.333333 4196 1.49E-06 0.309862398 04151///PI3K-Akt signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0101031///chaperone complex+++GO:1990565///HSP90-CDC37 chaperone complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019887///protein kinase regulator activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0031072///heat shock protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0043422///protein kinase B binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0097110///scaffold protein binding GO:0006457///protein folding+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045859///regulation of protein kinase activity+++GO:0050821///protein stabilization+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization 12540 12540 'Cdc42' mRNA 8643.6 9032.92 8338.27 219.74 226.64 225.41 368.26 364.76 367 223.93 366.6733333 16550.77 15927.32 15968.3 8671.596667 16148.79667 7.82E-81 0.885769607 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04660///T cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04912///GnRH signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++05100///Bacterial invasion of epithelial cells+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05417///Lipid and atherosclerosis GO:0000139///Golgi membrane+++GO:0000322///storage vacuole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0017119///Golgi transport complex+++GO:0030141///secretory granule+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0031252///cell leading edge+++GO:0031256///leading edge membrane+++GO:0031258///lamellipodium membrane+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043209///myelin sheath+++GO:0045177///apical part of cell+++GO:0045335///phagocytic vesicle+++GO:0051233///spindle midzone+++GO:0071944///cell periphery+++GO:0072686///mitotic spindle+++GO:0098685///Schaffer collateral - CA1 synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0030742///GTP-dependent protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0031996///thioesterase binding+++GO:0032427///GBD domain binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0042802///identical protein binding+++GO:0051022///Rho GDP-dissociation inhibitor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0002040///sprouting angiogenesis+++GO:0003161///cardiac conduction system development+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0007030///Golgi organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0007097///nuclear migration+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007229///integrin-mediated signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0007399///nervous system development+++GO:0010591///regulation of lamellipodium assembly+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016197///endosomal transport+++GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031333///negative regulation of protein complex assembly+++GO:0032467///positive regulation of cytokinesis+++GO:0032488///Cdc42 protein signal transduction+++GO:0034329///cell junction assembly+++GO:0034332///adherens junction organization+++GO:0034613///cellular protein localization+++GO:0035050///embryonic heart tube development+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0036336///dendritic cell migration+++GO:0038189///neuropilin signaling pathway+++GO:0039694///viral RNA genome replication+++GO:0043085///positive regulation of catalytic activity+++GO:0043393///regulation of protein binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045740///positive regulation of DNA replication+++GO:0046330///positive regulation of JNK cascade+++GO:0046847///filopodium assembly+++GO:0048549///positive regulation of pinocytosis+++GO:0048664///neuron fate determination+++GO:0051301///cell division+++GO:0051489///regulation of filopodium assembly+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051647///nucleus localization+++GO:0051683///establishment of Golgi localization+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0060047///heart contraction+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060661///submandibular salivary gland formation+++GO:0060997///dendritic spine morphogenesis+++GO:0071346///cellular response to interferon-gamma+++GO:0072384///organelle transport along microtubule+++GO:0086101///endothelin receptor signaling pathway involved in heart process+++GO:0090135///actin filament branching+++GO:0090316///positive regulation of intracellular protein transport+++GO:0098609///cell-cell adhesion+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0099563///modification of synaptic structure+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:2000251///positive regulation of actin cytoskeleton reorganization" 12544 12544 'Cdc45' mRNA 251 253.02 238 4.24 4.31 4.14 5.05 4.74 5.17 4.23 4.986666667 298 256 296 247.34 283.3333333 0.30386134 0.183983754 04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0031261///DNA replication preinitiation complex+++GO:0036064///ciliary basal body GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0007049///cell cycle+++GO:0031938///regulation of chromatin silencing at telomere+++GO:1902977///mitotic DNA replication preinitiation complex assembly 12545 12545 'Cdc7' mRNA 122 129 144 2.28 2.41 2.86 3.11 3.67 3.62 2.516666667 3.466666667 193 222 218 131.6666667 211 0.001099263 0.666841975 04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000727///double-strand break repair via break-induced replication+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0044770///cell cycle phase transition+++GO:0051301///cell division 12549 12549 'Arhgap31' mRNA 943 1084 749 6.43 7.27 5.42 7.4 6.97 7.56 6.373333333 7.31 1249 1150 1237 925.3333333 1212 3.80E-04 0.383424133 GO:0005925///focal adhesion+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 12550 12550 'Cdh1' mRNA 4215 4365 4381 51.08 52.02 56.31 69.87 64.27 64.82 53.13666667 66.32 6637 5964 5964 4320.333333 6188.333333 3.97E-15 0.50429424 04015///Rap1 signaling pathway+++04371///Apelin signaling pathway+++04390///Hippo signaling pathway+++04514///Cell adhesion molecules+++04520///Adherens junction+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030864///cortical actin cytoskeleton+++GO:0033268///node of Ranvier+++GO:0043219///lateral loop+++GO:0043220///Schmidt-Lanterman incisure+++GO:0043296///apical junction complex+++GO:0043679///axon terminus+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008092///cytoskeletal protein binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030506///ankyrin binding+++GO:0032794///GTPase activating protein binding+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding "GO:0001701///in utero embryonic development+++GO:0001829///trophectodermal cell differentiation+++GO:0003382///epithelial cell morphogenesis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0007566///embryo implantation+++GO:0007605///sensory perception of sound+++GO:0009636///response to toxic substance+++GO:0010468///regulation of gene expression+++GO:0010955///negative regulation of protein processing+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0019538///protein metabolic process+++GO:0021983///pituitary gland development+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0031175///neuron projection development+++GO:0031532///actin cytoskeleton reorganization+++GO:0032880///regulation of protein localization+++GO:0033561///regulation of water loss via skin+++GO:0034332///adherens junction organization+++GO:0035847///uterine epithelium development+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046697///decidualization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060576///intestinal epithelial cell development+++GO:0060662///salivary gland cavitation+++GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0070830///bicellular tight junction assembly+++GO:0071230///cellular response to amino acid stimulus+++GO:0071285///cellular response to lithium ion+++GO:0071681///cellular response to indole-3-methanol+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090102///cochlea development+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000008///regulation of protein localization to cell surface+++GO:2001222///regulation of neuron migration" 12552 12552 'Cdh11' mRNA 1949 2158 1855 20.26 22.05 20.49 14.79 13.83 15.95 20.93333333 14.85666667 1640 1495 1706 1987.333333 1613.666667 9.47E-05 -0.310834244 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0021957///corticospinal tract morphogenesis+++GO:0034332///adherens junction organization+++GO:0043588///skin development+++GO:0050804///modulation of chemical synaptic transmission+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 12554 12554 'Cdh13' mRNA 49 54 53 0.68 0.78 0.8 0.29 0.21 0.24 0.753333333 0.246666667 24 16 19 52 19.66666667 8.96E-04 -1.418133926 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016342///catenin complex+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098982///GABA-ergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0055100///adiponectin binding+++GO:0071813///lipoprotein particle binding GO:0000278///mitotic cell cycle+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002040///sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0007266///Rho protein signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016601///Rac protein signal transduction+++GO:0030032///lamellipodium assembly+++GO:0030100///regulation of endocytosis+++GO:0030335///positive regulation of cell migration+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0043542///endothelial cell migration+++GO:0043616///keratinocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051668///localization within membrane+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 12555 12555 'Cdh15' mRNA 107 103 84 2.08 1.97 1.73 0.35 0.22 0.3 1.926666667 0.29 21 13 17 98 17 1.51E-12 -2.537298869 04514///Cell adhesion molecules GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0031594///neuromuscular junction GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 12556 12556 'Cdh16' mRNA 7.03 2 4 0.13 0.04 0.08 0.04 0.07 0.19 0.083333333 0.1 2.77 4 11.16 4.343333333 5.976666667 0.814491863 0.379726978 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 12558 12558 'Cdh2' mRNA 629 571 571 6.49 5.96 6.33 3.61 2.82 3.04 6.26 3.156666667 400 301 316.99 590.3333333 339.33 9.17E-10 -0.814328887 04514///Cell adhesion molecules+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005916///fascia adherens+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016342///catenin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0030864///cortical actin cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0044853///plasma membrane raft+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045294///alpha-catenin binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0050998///nitric-oxide synthase binding "GO:0003323///type B pancreatic cell development+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007416///synapse assembly+++GO:0007420///brain development+++GO:0009966///regulation of signal transduction+++GO:0010001///glial cell differentiation+++GO:0014032///neural crest cell development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016477///cell migration+++GO:0021537///telencephalon development+++GO:0021987///cerebral cortex development+++GO:0031641///regulation of myelination+++GO:0032880///regulation of protein localization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0048514///blood vessel morphogenesis+++GO:0048854///brain morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050770///regulation of axonogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051146///striated muscle cell differentiation+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060019///radial glial cell differentiation+++GO:0060563///neuroepithelial cell differentiation+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090497///mesenchymal cell migration+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0097150///neuronal stem cell population maintenance+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:2000809///positive regulation of synaptic vesicle clustering" 12560 12560 'Cdh3' mRNA 307 372 316 4.1 4.89 4.48 2.66 2.52 2.95 4.49 2.71 229 212 246 331.6666667 229 6.46E-04 -0.544962259 04514///Cell adhesion molecules GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0030054///cell junction GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0001895///retina homeostasis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0022405///hair cycle process+++GO:0031424///keratinization+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0051796///negative regulation of timing of catagen+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:1902910///positive regulation of melanosome transport 12561 12561 'Cdh4' mRNA 783 761 797 6.95 6.56 7.46 1 0.56 0.51 6.99 0.69 132 71 66 780.3333333 89.66666667 9.29E-67 -3.139896046 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007411///axon guidance+++GO:0045773///positive regulation of axon extension+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 12562 12562 'Cdh5' mRNA 268 236 173 3.63 3.14 2.49 8.23 7.52 7.98 3.086666667 7.91 700 624 657 225.6666667 660.3333333 3.58E-28 1.542262467 04514///Cell adhesion molecules+++04670///Leukocyte transendothelial migration+++05418///Fluid shear stress and atherosclerosis GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0030054///cell junction+++GO:0031965///nuclear membrane+++GO:0071944///cell periphery GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019903///protein phosphatase binding+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0044325///ion channel binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0070051///fibrinogen binding+++GO:0070700///BMP receptor binding+++GO:1990782///protein tyrosine kinase binding GO:0000902///cell morphogenesis+++GO:0001932///regulation of protein phosphorylation+++GO:0001944///vasculature development+++GO:0001955///blood vessel maturation+++GO:0006874///cellular calcium ion homeostasis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030335///positive regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031334///positive regulation of protein complex assembly+++GO:0034332///adherens junction organization+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043114///regulation of vascular permeability+++GO:0043534///blood vessel endothelial cell migration+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0045766///positive regulation of angiogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0070830///bicellular tight junction assembly+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:1902396///protein localization to bicellular tight junction+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:2000114///regulation of establishment of cell polarity+++GO:2000352///negative regulation of endothelial cell apoptotic process 12563 12563 'Cdh6' mRNA 147 121 134 0.94 0.77 0.91 0.46 0.47 0.55 0.873333333 0.493333333 83 82 96 134 87 0.010843997 -0.635825876 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0030054///cell junction GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 12564 12564 'Cdh8' mRNA 3 1 0 0.02 0.02 0 0 0 0 0.013333333 0 0 0 0 1.333333333 0 0.489543081 -2.838520661 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0043083///synaptic cleft+++GO:0043679///axon terminus+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding "GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0009409///response to cold+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050807///regulation of synapse organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules" 12565 12565 'Cdh9' mRNA 10 12 13 0.16 0.18 0.21 0.03 0.1 0.03 0.183333333 0.053333333 2 7 2 11.66666667 3.666666667 0.099829322 -1.678401207 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0098641///cadherin binding involved in cell-cell adhesion GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007416///synapse assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0099560///synaptic membrane adhesion 12566 12566 'Cdk2' mRNA 521 528 458 12.17 12.14 11.56 16.2 16.77 15.31 11.95666667 16.09333333 787 801 724 502.3333333 770.6666667 1.20E-08 0.607984519 04068///FoxO signaling pathway+++04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05215///Prostate cancer+++05222///Small cell lung cancer+++05226///Gastric cancer "GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000781///chromosome, telomeric region+++GO:0000793///condensed chromosome+++GO:0000805///X chromosome+++GO:0000806///Y chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015030///Cajal body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097123///cyclin A1-CDK2 complex+++GO:0097124///cyclin A2-CDK2 complex+++GO:0097134///cyclin E1-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0030332///cyclin binding+++GO:0035173///histone kinase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0097472///cyclin-dependent protein kinase activity "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006813///potassium ion transport+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007099///centriole replication+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0032869///cellular response to insulin stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051591///response to cAMP+++GO:0051602///response to electrical stimulus+++GO:0060968///regulation of gene silencing" 12567 12567 'Cdk4' mRNA 2111 2100 2057 89.56 87.8 92.77 143.22 137.71 142.73 90.04333333 141.22 3911 3656 3758 2089.333333 3775 2.78E-42 0.840978594 01522///Endocrine resistance+++04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04530///Tight junction+++04660///T cell receptor signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05212///Pancreatic cancer+++05214///Glioma+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0097129///cyclin D2-CDK4 complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0044877///protein-containing complex binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0002088///lens development in camera-type eye+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0031100///animal organ regeneration+++GO:0032869///cellular response to insulin stimulus+++GO:0033574///response to testosterone+++GO:0040014///regulation of multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046890///regulation of lipid biosynthetic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050994///regulation of lipid catabolic process+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0055093///response to hyperoxia+++GO:0060612///adipose tissue development+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071353///cellular response to interleukin-4+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:1904637///cellular response to ionomycin 12568 12568 'Cdk5' mRNA 792 871 855 21.91 23.52 25.14 25.05 25.48 22.83 23.52333333 24.45333333 1054 1045 932 839.3333333 1010.333333 0.015472573 0.254505176 04360///Axon guidance+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016533///protein kinase 5 complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005176///ErbB-2 class receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030549///acetylcholine receptor activator activity+++GO:0043125///ErbB-3 class receptor binding+++GO:0046875///ephrin receptor binding+++GO:0050321///tau-protein kinase activity+++GO:0051879///Hsp90 protein binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0001764///neuron migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001963///synaptic transmission, dopaminergic+++GO:0006468///protein phosphorylation+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006913///nucleocytoplasmic transport+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0007049///cell cycle+++GO:0007160///cell-matrix adhesion+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007416///synapse assembly+++GO:0007519///skeletal muscle tissue development+++GO:0008045///motor neuron axon guidance+++GO:0008306///associative learning+++GO:0008542///visual learning+++GO:0009611///response to wounding+++GO:0014044///Schwann cell development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019233///sensory perception of pain+++GO:0021537///telencephalon development+++GO:0021549///cerebellum development+++GO:0021695///cerebellar cortex development+++GO:0021697///cerebellar cortex formation+++GO:0021766///hippocampus development+++GO:0021819///layer formation in cerebral cortex+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0022038///corpus callosum development+++GO:0030182///neuron differentiation+++GO:0030334///regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031914///negative regulation of synaptic plasticity+++GO:0032092///positive regulation of protein binding+++GO:0032801///receptor catabolic process+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035418///protein localization to synapse+++GO:0042220///response to cocaine+++GO:0042501///serine phosphorylation of STAT protein+++GO:0043113///receptor clustering+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045055///regulated exocytosis+++GO:0045786///negative regulation of cell cycle+++GO:0045860///positive regulation of protein kinase activity+++GO:0045861///negative regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0046777///protein autophosphorylation+++GO:0046826///negative regulation of protein export from nucleus+++GO:0048148///behavioral response to cocaine+++GO:0048167///regulation of synaptic plasticity+++GO:0048488///synaptic vesicle endocytosis+++GO:0048489///synaptic vesicle transport+++GO:0048511///rhythmic process+++GO:0048709///oligodendrocyte differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0051301///cell division+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0070509///calcium ion import+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0098883///synapse pruning+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1904646///cellular response to amyloid-beta" 12569 12569 'Cdk5r1' mRNA 16 15 9 0.21 0.19 0.12 0.1 0.18 0.17 0.173333333 0.15 9 16 15 13.33333333 13.33333333 0.998591786 0.001810994 05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016533///protein kinase 5 complex+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043292///contractile fiber+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse GO:0002020///protease binding+++GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0045296///cadherin binding+++GO:0046875///ephrin receptor binding+++GO:0051015///actin filament binding+++GO:0051879///Hsp90 protein binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity "GO:0001764///neuron migration+++GO:0007158///neuron cell-cell adhesion+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0007420///brain development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021549///cerebellum development+++GO:0021722///superior olivary nucleus maturation+++GO:0021766///hippocampus development+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021819///layer formation in cerebral cortex+++GO:0030182///neuron differentiation+++GO:0030517///negative regulation of axon extension+++GO:0031175///neuron projection development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0042501///serine phosphorylation of STAT protein+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048013///ephrin receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0070315///G1 to G0 transition involved in cell differentiation+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0098693///regulation of synaptic vesicle cycle+++GO:2000273///positive regulation of signaling receptor activity" 12570 12570 'Cdk5r2' mRNA 0 0 2 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016533///protein kinase 5 complex+++GO:0030426///growth cone+++GO:0043005///neuron projection GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0008289///lipid binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity GO:0001764///neuron migration+++GO:0021549///cerebellum development+++GO:0021722///superior olivary nucleus maturation+++GO:0021766///hippocampus development+++GO:0021819///layer formation in cerebral cortex+++GO:0032147///activation of protein kinase activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0045956///positive regulation of calcium ion-dependent exocytosis 12571 12571 'Cdk6' mRNA 367.53 376.7 315.09 1.65 1.66 1.51 5.75 5.59 5.66 1.606666667 5.666666667 1474.39 1405.01 1400.01 353.1066667 1426.47 1.63E-101 2.006324959 04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04934///Cushing syndrome+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05212///Pancreatic cancer+++05214///Glioma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016592///mediator complex+++GO:0042995///cell projection+++GO:0097132///cyclin D2-CDK6 complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0098770///FBXO family protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003323///type B pancreatic cell development+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007219///Notch signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0036275///response to 5-fluorouracil+++GO:0042063///gliogenesis+++GO:0042127///regulation of cell proliferation+++GO:0043697///cell dedifferentiation+++GO:0044838///cell quiescence+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0045656///negative regulation of monocyte differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0060218///hematopoietic stem cell differentiation+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:2000773///negative regulation of cellular senescence 12572 12572 'Cdk7' mRNA 1481.32 1338.1 1425.98 10.27 9.12 10.49 8.46 8.08 8.4 9.96 8.313333333 1404.34 1310.64 1351.57 1415.133333 1355.516667 0.468356604 -0.075754501 03022///Basal transcription factors+++03420///Nucleotide excision repair+++04110///Cell cycle GO:0000439///transcription factor TFIIH core complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005675///transcription factor TFIIH holo complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0070516///CAK-ERCC2 complex+++GO:0070985///transcription factor TFIIK complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding GO:0006281///DNA repair+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain 12575 12575 'Cdkn1a' mRNA 3197 3125 2912 95.6 92.09 92.39 163.04 171.49 169.75 93.36 168.0933333 6269 6438 6319 3078 6342 9.27E-75 1.032618762 "01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04630///JAK-STAT signaling pathway+++04921///Oxytocin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0070557///PCNA-p21 complex GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0019912///cyclin-dependent protein kinase activating kinase activity+++GO:0030332///cyclin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006606///protein import into nucleus+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0007346///regulation of mitotic cell cycle+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0009411///response to UV+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010165///response to X-ray+++GO:0010243///response to organonitrogen compound+++GO:0010629///negative regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0016310///phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0030890///positive regulation of B cell proliferation+++GO:0031100///animal organ regeneration+++GO:0031668///cellular response to extracellular stimulus+++GO:0032091///negative regulation of protein binding+++GO:0034198///cellular response to amino acid starvation+++GO:0034605///cellular response to heat+++GO:0042060///wound healing+++GO:0042246///tissue regeneration+++GO:0042326///negative regulation of phosphorylation+++GO:0042493///response to drug+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043066///negative regulation of apoptotic process+++GO:0043068///positive regulation of programmed cell death+++GO:0043086///negative regulation of catalytic activity+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0046685///response to arsenic-containing substance+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051384///response to glucocorticoid+++GO:0051412///response to corticosterone+++GO:0051726///regulation of cell cycle+++GO:0055093///response to hyperoxia+++GO:0060574///intestinal epithelial cell maturation+++GO:0071479///cellular response to ionizing radiation+++GO:0071480///cellular response to gamma radiation+++GO:0071493///cellular response to UV-B+++GO:0072331///signal transduction by p53 class mediator+++GO:0090398///cellular senescence+++GO:0090399///replicative senescence+++GO:1902806///regulation of cell cycle G1/S phase transition+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000278///regulation of DNA biosynthetic process+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process" 12576 12576 'Cdkn1b' mRNA 833 766 766 19.36 17.53 18.89 13.3 12.09 12.57 18.59333333 12.65333333 658 584 602 788.3333333 614.6666667 4.38E-04 -0.371678716 01522///Endocrine resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04151///PI3K-Akt signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++05162///Measles+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030332///cyclin binding+++GO:0030544///Hsp70 protein binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001666///response to hypoxia+++GO:0001890///placenta development+++GO:0006813///potassium ion transport+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007096///regulation of exit from mitosis+++GO:0007219///Notch signaling pathway+++GO:0007346///regulation of mitotic cell cycle+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0008219///cell death+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0030308///negative regulation of cell growth+++GO:0031116///positive regulation of microtubule polymerization+++GO:0032355///response to estradiol+++GO:0033673///negative regulation of kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0042326///negative regulation of phosphorylation+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043200///response to amino acid+++GO:0043434///response to peptide hormone+++GO:0045732///positive regulation of protein catabolic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0046686///response to cadmium ion+++GO:0048102///autophagic cell death+++GO:0048839///inner ear development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0051726///regulation of cell cycle+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0071236///cellular response to antibiotic+++GO:0071285///cellular response to lithium ion+++GO:0071407///cellular response to organic cyclic compound+++GO:0071850///mitotic cell cycle arrest+++GO:1902746///regulation of lens fiber cell differentiation+++GO:1902806///regulation of cell cycle G1/S phase transition+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration" 12577 12577 'Cdkn1c' mRNA 905 928 309 26.78 27.19 9.74 8.36 11.48 11.98 21.23666667 10.60666667 324 433 450 714 402.3333333 0.134130767 -0.813683925 04110///Cell cycle GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001822///kidney development+++GO:0001890///placenta development+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007096///regulation of exit from mitosis+++GO:0007346///regulation of mitotic cell cycle+++GO:0007568///aging+++GO:0016310///phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0030325///adrenal gland development+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0033673///negative regulation of kinase activity+++GO:0035264///multicellular organism growth+++GO:0042326///negative regulation of phosphorylation+++GO:0042551///neuron maturation+++GO:0043010///camera-type eye development+++GO:0043086///negative regulation of catalytic activity+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0055123///digestive system development+++GO:0060065///uterus development+++GO:0060669///embryonic placenta morphogenesis+++GO:0071514///genetic imprinting+++GO:1902746///regulation of lens fiber cell differentiation+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity" 12579 12579 'Cdkn2b' mRNA 79 83 96 3.39 3.51 4.37 6.69 6.4 6.18 3.756666667 6.423333333 179 167 160 86 168.6666667 2.64E-05 0.95590123 04068///FoxO signaling pathway+++04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04934///Cushing syndrome+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0030219///megakaryocyte differentiation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0031670///cellular response to nutrient+++GO:0042326///negative regulation of phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048536///spleen development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0060253///negative regulation of glial cell proliferation+++GO:0070316///regulation of G0 to G1 transition+++GO:0090398///cellular senescence+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 12580 12580 'Cdkn2c' mRNA 31 32 29 1.51 1.79 1.74 2.68 3.11 2.81 1.68 2.866666667 58 68 67 30.66666667 64.33333333 0.003908828 1.059833775 01522///Endocrine resistance+++04110///Cell cycle+++04934///Cushing syndrome+++05166///Human T-cell leukemia virus 1 infection+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0030308///negative regulation of cell growth+++GO:0042326///negative regulation of phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048709///oligodendrocyte differentiation+++GO:0051726///regulation of cell cycle 12581 12581 'Cdkn2d' mRNA 2837 2834 2810 135.82 133.86 142.61 46.5 52.55 49.25 137.43 49.43333333 1116 1231 1143 2827 1163.333333 4.88E-64 -1.292590039 04068///FoxO signaling pathway+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097129///cyclin D2-CDK4 complex GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0009411///response to UV+++GO:0030308///negative regulation of cell growth+++GO:0032526///response to retinoic acid+++GO:0033280///response to vitamin D+++GO:0042326///negative regulation of phosphorylation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048102///autophagic cell death+++GO:0051726///regulation of cell cycle+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1902807///negative regulation of cell cycle G1/S phase transition 12583 12583 'Cdo1' mRNA 11137 11451 11296 379.83 384.98 408.71 210 233.99 208.9 391.1733333 217.63 7076 7695 6811 11294.66667 7194 2.71E-24 -0.662676346 00270///Cysteine and methionine metabolism+++00430///Taurine and hypotaurine metabolism GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0017172///cysteine dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0007595///lactation+++GO:0010243///response to organonitrogen compound+++GO:0019448///L-cysteine catabolic process+++GO:0019452///L-cysteine catabolic process to taurine+++GO:0019530///taurine metabolic process+++GO:0033762///response to glucagon+++GO:0042412///taurine biosynthetic process+++GO:0043200///response to amino acid+++GO:0045471///response to ethanol+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP 12585 12585 'Cdr2' mRNA 105 122 87 2.31 2.65 2.03 1.95 2.14 2.1 2.33 2.063333333 102 109 106 104.6666667 105.6666667 0.987918084 0.007634609 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 12587 12587 'Mia' mRNA 7669 7495 8024 1064.5 1037.23 1182.36 523.07 605.67 553.81 1094.696667 560.85 4295 4831 4380 7729.333333 4502 4.80E-26 -0.792950105 GO:0005576///extracellular region GO:0008083///growth factor activity GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0030198///extracellular matrix organization 12589 12589 'Ift81' mRNA 1408 1469 1341 27.1 28.37 27.66 11.28 11.06 11.68 27.71 11.34 690 638 679 1406 669 6.89E-38 -1.082770244 GO:0005813///centrosome+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097225///sperm midpiece+++GO:0097228///sperm principal piece GO:0005515///protein binding+++GO:0015631///tubulin binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly 12590 12590 'Cdx1' mRNA 2 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008327///methyl-CpG binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0009790///embryo development+++GO:0009887///animal organ morphogenesis+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0014807///regulation of somitogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060349///bone morphogenesis" 12593 12593 'Cdyl' mRNA 161 149 104 2.51 2.44 1.87 1.62 1.83 1.54 2.273333333 1.663333333 119 125 110 138 118 0.40217943 -0.230286997 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck "GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003824///catalytic activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016829///lyase activity+++GO:0030674///protein binding, bridging+++GO:0035064///methylated histone binding+++GO:0042802///identical protein binding+++GO:0120092///crotonyl-CoA hydratase activity" "GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0016573///histone acetylation+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060816///random inactivation of X chromosome+++GO:0120094///negative regulation of peptidyl-lysine crotonylation" 12606 12606 'Cebpa' mRNA 58 51 31 1.22 1.06 0.69 3.88 3.37 4.35 0.99 3.866666667 212 180 230 46.66666667 207.3333333 1.20E-17 2.146357978 04932///Non-alcoholic fatty liver disease+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0035189///Rb-E2F complex+++GO:0036488///CHOP-C/EBP complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001163///RNA polymerase I regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0071837///HMG box domain binding+++GO:0097677///STAT family protein binding" "GO:0000050///urea cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006360///transcription by RNA polymerase I+++GO:0007005///mitochondrion organization+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0008203///cholesterol metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030099///myeloid cell differentiation+++GO:0030225///macrophage differentiation+++GO:0030324///lung development+++GO:0030851///granulocyte differentiation+++GO:0042127///regulation of cell proliferation+++GO:0042593///glucose homeostasis+++GO:0043032///positive regulation of macrophage activation+++GO:0045444///fat cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0048469///cell maturation+++GO:0048839///inner ear development+++GO:0050729///positive regulation of inflammatory response+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0055088///lipid homeostasis+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071285///cellular response to lithium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:2000144///positive regulation of DNA-templated transcription, initiation" 12607 12607 'Cebpz' mRNA 602 675 651 8.01 8.78 9.13 7.72 7.54 8.39 8.64 7.883333333 672 640 707 642.6666667 673 0.71965158 0.053889902 GO:0005634///nucleus+++GO:0016602///CCAAT-binding factor complex GO:0003713///transcription coactivator activity GO:0045944///positive regulation of transcription by RNA polymerase II 12608 12608 'Cebpb' mRNA 80 69 17 3.11 2.64 0.7 5.14 2.91 5.31 2.15 4.453333333 152 84 152 55.33333333 129.3333333 0.002723141 1.231343339 04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05152///Tuberculosis+++05202///Transcriptional misregulation in cancer "GO:0000779///condensed chromosome, centromeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0036488///CHOP-C/EBP complex+++GO:0090575///RNA polymerase II transcription factor complex" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0035035///histone acetyltransferase binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0002432///granuloma formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007613///memory+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0032675///regulation of interleukin-6 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035711///T-helper 1 cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0042742///defense response to bacterium+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050729///positive regulation of inflammatory response+++GO:0050873///brown fat cell differentiation+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070169///positive regulation of biomineral tissue development+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071407///cellular response to organic cyclic compound+++GO:0072574///hepatocyte proliferation+++GO:0097421///liver regeneration+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901329///regulation of odontoblast differentiation+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:2001198///regulation of dendritic cell differentiation" 12609 12609 'Cebpd' mRNA 390.53 387.01 45.41 9.72 9.48 1.2 10.42 43.46 39.06 6.8 30.98 481.62 1961.24 1747.66 274.3166667 1396.84 0.02581973 2.382902229 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045444///fat cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development" 12611 12611 'Cebpg' mRNA 348 393 354 3.96 4.4 4.28 5.9 5.5 5.81 4.213333333 5.736666667 596.66 543 568.89 365 569.5166667 1.81E-07 0.628843388 05152///Tuberculosis GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044377///RNA polymerase II proximal promoter sequence-specific DNA binding, bending+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001889///liver development+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006955///immune response+++GO:0016071///mRNA metabolic process+++GO:0030183///B cell differentiation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043353///enucleate erythrocyte differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045739///positive regulation of DNA repair+++GO:0045944///positive regulation of transcription by RNA polymerase II" 12613 12613 'Cel' mRNA 10 3 4 0.27 0.08 0.12 0 0.07 0 0.156666667 0.023333333 0 3 0 5.666666667 1 0.159577683 -2.494545375 00100///Steroid biosynthesis+++00561///Glycerolipid metabolism+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0032991///protein-containing complex+++GO:0042588///zymogen granule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0099060///integral component of postsynaptic specialization membrane "GO:0004622///lysophospholipase activity+++GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0008126///acetylesterase activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0038023///signaling receptor activity+++GO:0042043///neurexin family protein binding+++GO:0043208///glycosphingolipid binding+++GO:0044877///protein-containing complex binding+++GO:0050253///retinyl-palmitate esterase activity+++GO:0052689///carboxylic ester hydrolase activity" GO:0006629///lipid metabolic process+++GO:0006707///cholesterol catabolic process+++GO:0007158///neuron cell-cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0016042///lipid catabolic process+++GO:0030157///pancreatic juice secretion+++GO:0042572///retinol metabolic process+++GO:0046514///ceramide catabolic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly 12614 12614 'Celsr1' mRNA 1524 1438 1419 7.74 7.63 8.28 3.31 3.1 3.32 7.883333333 3.243333333 706 617 700 1460.333333 674.3333333 5.34E-37 -1.127334136 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001736///establishment of planar polarity+++GO:0001764///neuron migration+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007626///locomotory behavior+++GO:0009952///anterior/posterior pattern specification+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042060///wound healing+++GO:0042249///establishment of planar polarity of embryonic epithelium+++GO:0042472///inner ear morphogenesis+++GO:0045176///apical protein localization+++GO:0048105///establishment of body hair planar orientation+++GO:0060488///orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis+++GO:0060489///planar dichotomous subdivision of terminal units involved in lung branching morphogenesis+++GO:0060490///lateral sprouting involved in lung morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090251///protein localization involved in establishment of planar polarity+++GO:0098609///cell-cell adhesion 12615 12615 'Cenpa' mRNA 38 40 53 1.74 1.86 2.58 16.91 15.67 17.1 2.06 16.56 442 402 432 43.66666667 425.3333333 3.66E-60 3.268429221 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000786///nucleosome+++GO:0000939///condensed chromosome inner kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin" GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity "GO:0000132///establishment of mitotic spindle orientation+++GO:0000281///mitotic cytokinesis+++GO:0051382///kinetochore assembly+++GO:0071459///protein localization to chromosome, centromeric region" 12616 12616 'Cenpb' mRNA 680 676 589 13.52 13.23 12.42 19.8 19.71 18.84 13.05666667 19.45 1146 1114 1056 648.3333333 1105.333333 1.17E-16 0.759891543 "GO:0000775///chromosome, centromeric region+++GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0016604///nuclear body" GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003696///satellite DNA binding 12617 12617 'Cenpc1' mRNA 508.63 535.29 524.87 7.26 7.88 8.52 6.43 6.2 6 7.886666667 6.21 485.17 458.1 443.56 522.93 462.2766667 0.146129829 -0.189903999 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0016604///nuclear body+++GO:0030496///midbody" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019237///centromeric DNA binding+++GO:0042802///identical protein binding GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051382///kinetochore assembly+++GO:0051455///attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation 12626 12626 'Cetn3' mRNA 1498.38 1481.14 1417.22 77.67 75.75 81.65 81.39 86.11 84.73 78.35666667 84.07666667 1656.01 1700.59 1669.21 1465.58 1675.27 0.022809202 0.181880691 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0044615///nuclear pore nuclear basket+++GO:0070390///transcription export complex 2 GO:0005509///calcium ion binding+++GO:0008017///microtubule binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051301///cell division 12628 12628 'Cfh' mRNA 648.98 709.96 647.91 7.99 8.6 8.46 35.81 32.48 34.31 8.35 34.2 3348 2966.85 3106.83 668.95 3140.56 1.71E-192 2.220803456 04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0001851///complement component C3b binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0043395///heparan sulfate proteoglycan binding "GO:0001525///angiogenesis+++GO:0001780///neutrophil homeostasis+++GO:0001822///kidney development+++GO:0001905///activation of membrane attack complex+++GO:0002021///response to dietary excess+++GO:0002251///organ or tissue specific immune response+++GO:0002376///immune system process+++GO:0002434///immune complex clearance+++GO:0003406///retinal pigment epithelium development+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0007005///mitochondrion organization+++GO:0007601///visual perception+++GO:0008340///determination of adult lifespan+++GO:0010467///gene expression+++GO:0016064///immunoglobulin mediated immune response+++GO:0030449///regulation of complement activation+++GO:0032042///mitochondrial DNA metabolic process+++GO:0032835///glomerulus development+++GO:0034097///response to cytokine+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0045087///innate immune response+++GO:0046034///ATP metabolic process+++GO:0046530///photoreceptor cell differentiation+++GO:0046548///retinal rod cell development+++GO:0050905///neuromuscular process+++GO:0051216///cartilage development+++GO:0051640///organelle localization+++GO:0060041///retina development in camera-type eye+++GO:0060348///bone development+++GO:0070487///monocyte aggregation+++GO:0070527///platelet aggregation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090594///inflammatory response to wounding+++GO:0097273///creatinine homeostasis+++GO:0140053///mitochondrial gene expression+++GO:1903659///regulation of complement-dependent cytotoxicity" 12630 12630 'Cfi' mRNA 138 144 150 3.77 3.88 4.35 5.13 5.25 5.62 4 5.333333333 216 216 229 144 220.3333333 0.00161049 0.600547059 04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0016020///membrane GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response" 12631 12631 'Cfl1' mRNA 10378 10449 9994 539.77 536.77 551.51 1477.27 1453.39 1484.97 542.6833333 1471.876667 32594 31272 31679 10273.66667 31848.33333 9.13E-282 1.620352832 04360///Axon guidance+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++05170///Human immunodeficiency virus 1 infection GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031252///cell leading edge+++GO:0031258///lamellipodium membrane+++GO:0031966///mitochondrial membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0090732///cofilin-actin rod+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0051015///actin filament binding+++GO:1902936///phosphatidylinositol bisphosphate binding GO:0000281///mitotic cytokinesis+++GO:0001755///neural crest cell migration+++GO:0001842///neural fold formation+++GO:0006468///protein phosphorylation+++GO:0006606///protein import into nucleus+++GO:0006928///movement of cell or subcellular component+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007162///negative regulation of cell adhesion+++GO:0009615///response to virus+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010593///negative regulation of lamellipodium assembly+++GO:0022604///regulation of cell morphogenesis+++GO:0030010///establishment of cell polarity+++GO:0030030///cell projection organization+++GO:0030042///actin filament depolymerization+++GO:0030043///actin filament fragmentation+++GO:0030307///positive regulation of cell growth+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0040019///positive regulation of embryonic development+++GO:0043200///response to amino acid+++GO:0044794///positive regulation by host of viral process+++GO:0045792///negative regulation of cell size+++GO:0045862///positive regulation of proteolysis+++GO:0048870///cell motility+++GO:0051014///actin filament severing+++GO:0051293///establishment of spindle localization+++GO:0051511///negative regulation of unidimensional cell growth+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060999///positive regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:1902951///negative regulation of dendritic spine maintenance+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:1905873///positive regulation of protein localization to cell leading edge+++GO:1905875///negative regulation of postsynaptic density organization+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2000146///negative regulation of cell motility+++GO:2000147///positive regulation of cell motility+++GO:2000784///positive regulation of establishment of cell polarity regulating cell shape+++GO:2000814///positive regulation of barbed-end actin filament capping 12632 12632 'Cfl2' mRNA 1656 1654 1519 30.36 29.78 30.02 34.18 32.32 35.2 30.05333333 33.9 2112 1949 2112 1609.666667 2057.666667 1.58E-06 0.343195765 04360///Axon guidance+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016363///nuclear matrix+++GO:0030018///Z disc+++GO:0031674///I band GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007519///skeletal muscle tissue development+++GO:0030042///actin filament depolymerization+++GO:0030043///actin filament fragmentation+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0045214///sarcomere organization+++GO:0046716///muscle cell cellular homeostasis+++GO:0048870///cell motility+++GO:0051014///actin filament severing 12633 12633 'Cflar' mRNA 2200.56 2305.23 2186.95 20.5 21.22 21.21 26.11 22.93 23.99 20.97666667 24.34333333 3313.06 2830.33 3075.43 2230.913333 3072.94 1.48E-10 0.449219294 04064///NF-kappa B signaling pathway+++04140///Autophagy - animal+++04210///Apoptosis+++04217///Necroptosis+++04668///TNF signaling pathway+++05142///Chagas disease+++05160///Hepatitis C GO:0005737///cytoplasm+++GO:0031264///death-inducing signaling complex+++GO:0031265///CD95 death-inducing signaling complex+++GO:0045121///membrane raft+++GO:0097342///ripoptosome GO:0002020///protease binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016504///peptidase activator activity+++GO:0044877///protein-containing complex binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis GO:0001666///response to hypoxia+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007519///skeletal muscle tissue development+++GO:0009617///response to bacterium+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0014732///skeletal muscle atrophy+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0014866///skeletal myofibril assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0033574///response to testosterone+++GO:0042060///wound healing+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0050790///regulation of catalytic activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060544///regulation of necroptotic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0097190///apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:1901740///negative regulation of myoblast fusion+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903055///positive regulation of extracellular matrix organization+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903845///negative regulation of cellular response to transforming growth factor beta stimulus+++GO:1903944///negative regulation of hepatocyte apoptotic process+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 12638 12638 'Cftr' mRNA 35 58 52 0.29 0.48 0.46 0.93 1.02 1.14 0.41 1.03 127 136 151 48.33333333 138 7.78E-08 1.501634773 02010///ABC transporters+++04024///cAMP signaling pathway+++04152///AMPK signaling pathway+++04530///Tight junction+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05110///Vibrio cholerae infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0034707///chloride channel complex+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane "GO:0000166///nucleotide binding+++GO:0005254///chloride channel activity+++GO:0005260///intracellularly ATP-gated chloride channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019899///enzyme binding+++GO:0030165///PDZ domain binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0051087///chaperone binding+++GO:0106138///Sec61 translocon complex binding" GO:0003254///regulation of membrane depolarization+++GO:0006695///cholesterol biosynthetic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006833///water transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0009410///response to xenobiotic stimulus+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0015705///iodide transport+++GO:0030301///cholesterol transport+++GO:0030321///transepithelial chloride transport+++GO:0030324///lung development+++GO:0033005///positive regulation of mast cell activation+++GO:0034220///ion transmembrane transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035377///transepithelial water transport+++GO:0035725///sodium ion transmembrane transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0036253///response to amiloride+++GO:0042311///vasodilation+++GO:0045921///positive regulation of exocytosis+++GO:0048240///sperm capacitation+++GO:0050891///multicellular organismal water homeostasis+++GO:0051454///intracellular pH elevation+++GO:0055085///transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0070166///enamel mineralization+++GO:0070175///positive regulation of enamel mineralization+++GO:0071320///cellular response to cAMP+++GO:0097186///amelogenesis+++GO:1902161///positive regulation of cyclic nucleotide-gated ion channel activity+++GO:1902476///chloride transmembrane transport+++GO:1902943///positive regulation of voltage-gated chloride channel activity+++GO:1904322///cellular response to forskolin+++GO:1904446///positive regulation of establishment of Sertoli cell barrier+++GO:1905460///negative regulation of vascular associated smooth muscle cell apoptotic process+++GO:2000077///negative regulation of type B pancreatic cell development 12640 12640 'Cga' mRNA 0 0 1 0 0 0.11 0 0.19 0.1 0.036666667 0.096666667 0 2 1 0.333333333 1 0.726099345 1.486127565 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04917///Prolactin signaling pathway+++04918///Thyroid hormone synthesis+++04923///Regulation of lipolysis in adipocytes+++04929///GnRH secretion+++05320///Autoimmune thyroid disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016914///follicle-stimulating hormone complex GO:0005179///hormone activity+++GO:0016913///follicle-stimulating hormone activity GO:0006590///thyroid hormone generation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008406///gonad development+++GO:0010469///regulation of signaling receptor activity+++GO:0010893///positive regulation of steroid biosynthetic process+++GO:0030878///thyroid gland development+++GO:0032275///luteinizing hormone secretion+++GO:0032870///cellular response to hormone stimulus+++GO:0046621///negative regulation of organ growth+++GO:0046884///follicle-stimulating hormone secretion+++GO:0048589///developmental growth 12642 12642 'Ch25h' mRNA 131 150 124 5.75 6.5 5.78 34.07 34.26 32.54 6.01 33.62333333 891 874 823 135 862.6666667 1.27E-96 2.665849621 00120///Primary bile acid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000254///C-4 methylsterol oxidase activity+++GO:0001567///cholesterol 25-hydroxylase activity+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0035754///B cell chemotaxis 12643 12643 'Chad' mRNA 1435 1570 1380 49.67 53.57 50.67 12.41 13.73 11.3 51.30333333 12.48 412 445 363 1461.666667 406.6666667 6.69E-77 -1.855642565 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0060348///bone development+++GO:1900155///negative regulation of bone trabecula formation 12648 12648 'Chd1' mRNA 525 499 294 3.9 3.88 2.15 2.25 2.44 2.87 3.31 2.52 385 393 478 439.3333333 418.6666667 0.776160871 -0.069459836 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0035064///methylated histone binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006338///chromatin remodeling+++GO:0016569///covalent chromatin modification+++GO:0032508///DNA duplex unwinding+++GO:0043923///positive regulation by host of viral transcription 12649 12649 'Chek1' mRNA 13 10 14 0.21 0.15 0.21 0.81 0.98 1.03 0.19 0.94 59 69 73.63 12.33333333 67.21 1.66E-08 2.428540037 04110///Cell cycle+++04115///p53 signaling pathway+++04218///Cellular senescence+++05166///Human T-cell leukemia virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0035402///histone kinase activity (H3-T11 specific) "GO:0000077///DNA damage checkpoint+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001833///inner cell mass cell proliferation+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0006997///nucleus organization+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010468///regulation of gene expression+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010767///regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035407///histone H3-T11 phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0044818///mitotic G2/M transition checkpoint+++GO:0045787///positive regulation of cell cycle+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0046602///regulation of mitotic centrosome separation+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0071260///cellular response to mechanical stimulus+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:1902742///apoptotic process involved in development+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000615///regulation of histone H3-K9 acetylation" 12651 12651 'Chkb' mRNA 1002 994 979 33.05 32.32 34.26 33.64 32.82 34.64 33.21 33.7 1172 1116 1168 991.6666667 1152 0.024482877 0.203955651 00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004103///choline kinase activity+++GO:0004111///creatine kinase activity+++GO:0004305///ethanolamine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0031625///ubiquitin protein ligase binding" GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0007420///brain development+++GO:0007517///muscle organ development+++GO:0008654///phospholipid biosynthetic process+++GO:0016310///phosphorylation+++GO:0021549///cerebellum development+++GO:0030644///cellular chloride ion homeostasis+++GO:0046314///phosphocreatine biosynthetic process+++GO:0046474///glycerophospholipid biosynthetic process 12652 12652 'Chga' mRNA 265 322 295 7.94 9.51 9.38 0.73 1.52 1.48 8.943333333 1.243333333 28 57 55 294 46.66666667 3.61E-28 -2.663467997 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0042583///chromaffin granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0098992///neuronal dense core vesicle GO:0005515///protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002026///regulation of the force of heart contraction+++GO:0002551///mast cell chemotaxis+++GO:0006996///organelle organization+++GO:0033366///protein localization to secretory granule+++GO:0033604///negative regulation of catecholamine secretion+++GO:0042742///defense response to bacterium+++GO:0043303///mast cell degranulation+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045576///mast cell activation+++GO:0045907///positive regulation of vasoconstriction+++GO:0046676///negative regulation of insulin secretion+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0086030///adenylate cyclase-activating adrenergic receptor signaling pathway involved in cardiac muscle relaxation+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:1901215///negative regulation of neuron death+++GO:1901899///positive regulation of relaxation of cardiac muscle+++GO:2000707///positive regulation of dense core granule biogenesis 12653 12653 'Chgb' mRNA 192 217 205 4.52 5.03 5.12 0.45 0.63 0.59 4.89 0.556666667 22 30 28 204.6666667 26.66666667 7.33E-29 -2.951057925 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule GO:0005515///protein binding 12654 12654 'Chil1' mRNA 1598 1718 1669 54.62 58.09 60.61 143.89 148.94 139.65 57.77333333 144.16 4834 4891 4551 1661.666667 4758.666667 1.42E-109 1.505645793 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0004568///chitinase activity+++GO:0005515///protein binding+++GO:0008061///chitin binding GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0009612///response to mechanical stimulus+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0030324///lung development+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034612///response to tumor necrosis factor+++GO:0045766///positive regulation of angiogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070555///response to interleukin-1+++GO:0070741///response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor 12655 12655 'Chil3' mRNA 44 50.96 54 1.68 1.92 2.19 67.22 71.14 66.94 1.93 68.43333333 2019 2085 1945 49.65333333 2016.333333 2.07E-293 5.341719695 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0048237///rough endoplasmic reticulum lumen "GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0004568///chitinase activity+++GO:0008061///chitin binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019900///kinase binding+++GO:0030246///carbohydrate binding+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity" GO:0000272///polysaccharide catabolic process+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0032722///positive regulation of chemokine production 12659 12659 'Ovgp1' mRNA 83 65 66 1.83 1.41 1.54 0.75 0.69 0.79 1.593333333 0.743333333 39 35 40 71.33333333 38 0.007910831 -0.919812945 GO:0005576///extracellular region+++GO:0015630///microtubule cytoskeleton+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0035805///egg coat+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098595///perivitelline space GO:0004568///chitinase activity+++GO:0008061///chitin binding GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0007338///single fertilization+++GO:2000360///negative regulation of binding of sperm to zona pellucida 12660 12660 'Chka' mRNA 3676.66 3820.58 3676.2 47.72 48.85 50.97 29.47 28.43 28.97 49.18 28.95666667 2588.12 2387.88 2393.28 3724.48 2456.426667 1.85E-22 -0.613258938 00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004103///choline kinase activity+++GO:0004104///cholinesterase activity+++GO:0004305///ethanolamine kinase activity+++GO:0005524///ATP binding+++GO:0008144///drug binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033265///choline binding+++GO:0042802///identical protein binding GO:0006580///ethanolamine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0019695///choline metabolic process+++GO:1904681///response to 3-methylcholanthrene 12661 12661 'Chl1' mRNA 752 814 775 4.94 5.35 5.46 2.34 2.34 2.48 5.25 2.386666667 407 402 420 780.3333333 409.6666667 3.27E-18 -0.941603794 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045177///apical part of cell GO:0002020///protease binding+++GO:0005515///protein binding GO:0001764///neuron migration+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008344///adult locomotory behavior+++GO:0030154///cell differentiation+++GO:0031103///axon regeneration+++GO:0031175///neuron projection development+++GO:0035640///exploration behavior+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050890///cognition 12662 12662 'Chm' mRNA 573 633 658 6.31 6.88 7.67 8.42 8.29 7.55 6.953333333 8.086666667 879 844 765 621.3333333 829.3333333 4.91E-04 0.401977717 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005968///Rab-protein geranylgeranyltransferase complex GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding GO:0001568///blood vessel development+++GO:0006612///protein targeting to membrane+++GO:0006886///intracellular protein transport+++GO:0007264///small GTPase mediated signal transduction+++GO:0016192///vesicle-mediated transport+++GO:0018344///protein geranylgeranylation+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 12663 12663 'Chml' mRNA 144 157 142 1.25 1.34 1.31 0.99 0.87 1.1 1.3 0.986666667 132 113 141 147.6666667 128.6666667 0.402362936 -0.210361203 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005968///Rab-protein geranylgeranyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0016192///vesicle-mediated transport+++GO:0018344///protein geranylgeranylation+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 12667 12667 'Chrd' mRNA 140 139 89 2.44 2.32 1.7 4.14 3.99 4.96 2.153333333 4.363333333 282 267 318 122.6666667 289 2.36E-10 1.232021746 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0045545///syndecan binding GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001702///gastrulation with mouth forming second+++GO:0001707///mesoderm formation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007417///central nervous system development+++GO:0009953///dorsal/ventral pattern formation+++GO:0021919///BMP signaling pathway involved in spinal cord dorsal/ventral patterning+++GO:0030336///negative regulation of cell migration+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045785///positive regulation of cell adhesion 12669 12669 'Chrm1' mRNA 155.95 170.01 135 1.33 1.42 1.21 0.27 0.41 0.26 1.32 0.313333333 37 55.11 35 153.6533333 42.37 8.65E-12 -1.862667018 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04725///Cholinergic synapse+++04810///Regulation of actin cytoskeleton+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0098981///cholinergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0099529///neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0040012///regulation of locomotion+++GO:0043270///positive regulation of ion transport+++GO:0046541///saliva secretion+++GO:0050890///cognition+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0090316///positive regulation of intracellular protein transport+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 12671 12671 'Chrm3' mRNA 18 16 10 0.22 0.24 0.13 0.02 0.01 0.03 0.196666667 0.02 1 1 2 14.66666667 1.333333333 0.001937905 -3.460840427 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++04742///Taste transduction+++04810///Regulation of actin cytoskeleton+++04911///Insulin secretion+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0005515///protein binding+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0031789///G protein-coupled acetylcholine receptor binding+++GO:0042166///acetylcholine binding+++GO:0050997///quaternary ammonium group binding "GO:0003056///regulation of vascular smooth muscle contraction+++GO:0003063///negative regulation of heart rate by acetylcholine+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0019722///calcium-mediated signaling+++GO:0032412///regulation of ion transmembrane transporter activity+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046541///saliva secretion+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:1904695///positive regulation of vascular smooth muscle contraction+++GO:1905144///response to acetylcholine" 12672 12672 'Chrm4' mRNA 1 2 2 0.02 0.04 0.04 0.03 0.03 0.05 0.033333333 0.036666667 2 2 3 1.666666667 2.333333333 0.844396003 0.470225382 04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0042383///sarcolemma+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0030594///neurotransmitter receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0040012///regulation of locomotion+++GO:0050790///regulation of catalytic activity+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 12675 12675 'Chuk' mRNA 1165 1262 663 17.91 19.07 10.76 10.12 11.51 11.84 15.91333333 11.15666667 760 845 861 1030 822 0.292631789 -0.322179191 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008385///IkappaB kinase complex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0035631///CD40 receptor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008384///IkappaB kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding+++GO:1990459///transferrin receptor binding "GO:0002011///morphogenesis of an epithelial sheet+++GO:0003009///skeletal muscle contraction+++GO:0006468///protein phosphorylation+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007252///I-kappaB phosphorylation+++GO:0007266///Rho protein signal transduction+++GO:0007595///lactation+++GO:0008150///biological_process+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010034///response to acetate+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030316///osteoclast differentiation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032496///response to lipopolysaccharide+++GO:0032727///positive regulation of interferon-alpha production+++GO:0033194///response to hydroperoxide+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0034614///cellular response to reactive oxygen species+++GO:0035994///response to muscle stretch+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043200///response to amino acid+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051146///striated muscle cell differentiation+++GO:0051607///defense response to virus+++GO:0060749///mammary gland alveolus development+++GO:0061847///response to cholecystokinin+++GO:0071276///cellular response to cadmium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0098586///cellular response to virus" 12677 12677 'Vsx2' mRNA 0 0 1 0 0 0.02 0.01 0 0 0.006666667 0.003333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007601///visual perception+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0043010///camera-type eye development+++GO:0045165///cell fate commitment+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050896///response to stimulus+++GO:0060040///retinal bipolar neuron differentiation+++GO:0060042///retina morphogenesis in camera-type eye" 12683 12683 'Cidea' mRNA 627 602 600 33.29 31.57 33.8 18.46 23.44 20.15 32.88666667 20.68333333 399 494 421 609.6666667 438 1.70E-04 -0.487434965 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005811///lipid droplet GO:0005515///protein binding+++GO:0042803///protein homodimerization activity GO:0001659///temperature homeostasis+++GO:0001818///negative regulation of cytokine production+++GO:0006629///lipid metabolic process+++GO:0006915///apoptotic process+++GO:0008219///cell death+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0019915///lipid storage+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0035634///response to stilbenoid+++GO:0042981///regulation of apoptotic process+++GO:0050995///negative regulation of lipid catabolic process+++GO:0070417///cellular response to cold+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:1902510///regulation of apoptotic DNA fragmentation 12684 12684 'Cideb' mRNA 18.96 16.25 20.78 0.99 0.84 1.16 0.63 0.1 0.63 0.996666667 0.453333333 13.75 2.04 13.38 18.66333333 9.723333333 0.24090205 -0.971558154 GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding GO:0006915///apoptotic process+++GO:0010942///positive regulation of cell death+++GO:0042981///regulation of apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097194///execution phase of apoptosis+++GO:0097202///activation of cysteine-type endopeptidase activity 12686 12686 'Elovl3' mRNA 0 0 1 0 0 0.04 0.06 0 0 0.013333333 0.02 2 0 0 0.333333333 0.666666667 0.863090843 0.855344965 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0120162///positive regulation of cold-induced thermogenesis" 12695 12695 'Patj' mRNA 1327 1326 1165 11.32 11.39 10.56 5.37 4.45 5.04 11.09 4.953333333 717 579 624 1272.666667 640 2.74E-26 -1.002952462 04390///Hippo signaling pathway+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0035003///subapical complex+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0070160///tight junction GO:0005515///protein binding GO:0031023///microtubule organizing center organization+++GO:0035089///establishment of apical/basal cell polarity+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0120192///tight junction assembly 12696 12696 'Cirbp' mRNA 5216 5133 5053 245.26 238.67 253.48 100.75 98.82 99.43 245.8033333 99.66666667 2461 2353 2347 5134 2387 5.55E-80 -1.117353438 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008266///poly(U) RNA binding+++GO:0030371///translation repressor activity+++GO:0070181///small ribosomal subunit rRNA binding "GO:0009409///response to cold+++GO:0009411///response to UV+++GO:0017148///negative regulation of translation+++GO:0030308///negative regulation of cell growth+++GO:0034063///stress granule assembly+++GO:0045727///positive regulation of translation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0048255///mRNA stabilization+++GO:0070417///cellular response to cold+++GO:1902806///regulation of cell cycle G1/S phase transition" 12700 12700 'Cish' mRNA 249 227 185 4.5 4.06 3.55 6.96 5.34 5.79 4.036666667 6.03 442 331 353 220.3333333 375.3333333 4.06E-06 0.758241832 04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0046854///phosphatidylinositol phosphorylation 12702 12702 'Socs3' mRNA 442 457 406 8.95 9.11 8.72 47.8 47.94 47.02 8.926666667 47.58666667 2716 2660 2587 435 2654.333333 2.42E-238 2.598876976 "04120///Ubiquitin mediated proteolysis+++04380///Osteoclast differentiation+++04630///JAK-STAT signaling pathway+++04668///TNF signaling pathway+++04910///Insulin signaling pathway+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04935///Growth hormone synthesis, secretion and action+++05160///Hepatitis C+++05164///Influenza A+++05168///Herpes simplex virus 1 infection" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005942///phosphatidylinositol 3-kinase complex GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0001932///regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0043066///negative regulation of apoptotic process+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045595///regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0050728///negative regulation of inflammatory response+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060674///placenta blood vessel development+++GO:0060707///trophoblast giant cell differentiation+++GO:0060708///spongiotrophoblast differentiation+++GO:1990830///cellular response to leukemia inhibitory factor 12703 12703 'Socs1' mRNA 144 128 117 7.17 6.31 6.19 9.97 12.37 11.68 6.556666667 11.34 228 276 259 129.6666667 254.3333333 3.41E-07 0.963956729 "04120///Ubiquitin mediated proteolysis+++04380///Osteoclast differentiation+++04630///JAK-STAT signaling pathway+++04910///Insulin signaling pathway+++04917///Prolactin signaling pathway+++04930///Type II diabetes mellitus+++04935///Growth hormone synthesis, secretion and action+++05145///Toxoplasmosis+++05206///MicroRNAs in cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0031410///cytoplasmic vesicle+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0019210///kinase inhibitor activity+++GO:0019901///protein kinase binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity "GO:0001817///regulation of cytokine production+++GO:0001932///regulation of protein phosphorylation+++GO:0007259///JAK-STAT cascade+++GO:0009968///negative regulation of signal transduction+++GO:0010533///regulation of activation of Janus kinase activity+++GO:0016567///protein ubiquitination+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0043086///negative regulation of catalytic activity+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043377///negative regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045444///fat cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0071230///cellular response to amino acid stimulus+++GO:0071345///cellular response to cytokine stimulus+++GO:0071407///cellular response to organic cyclic compound" 12704 12704 'Cit' mRNA 107 92 103 0.63 0.53 0.64 1.67 1.6 1.76 0.6 1.676666667 324 302 332 100.6666667 319.3333333 1.54E-20 1.652278083 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005773///vacuole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030496///midbody+++GO:0031985///Golgi cisterna+++GO:0032154///cleavage furrow+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0001223///transcription coactivator binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0000910///cytokinesis+++GO:0006468///protein phosphorylation+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0016310///phosphorylation+++GO:0016358///dendrite development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030154///cell differentiation+++GO:0031032///actomyosin structure organization+++GO:0032467///positive regulation of cytokinesis+++GO:0035331///negative regulation of hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0045665///negative regulation of neuron differentiation+++GO:0048699///generation of neurons+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0051301///cell division+++GO:0051402///neuron apoptotic process 12705 12705 'Cited1' mRNA 805 765 826 61.46 55.36 65.26 66.36 72.96 73.01 60.69333333 70.77666667 1026 1092 1094 798.6666667 1070.666667 5.11E-05 0.409851811 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0050693///LBD domain binding+++GO:0070410///co-SMAD binding "GO:0000578///embryonic axis specification+++GO:0001570///vasculogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001890///placenta development+++GO:0002009///morphogenesis of an epithelium+++GO:0003340///negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006913///nucleocytoplasmic transport+++GO:0006915///apoptotic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030318///melanocyte differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0032868///response to insulin+++GO:0034097///response to cytokine+++GO:0034341///response to interferon-gamma+++GO:0042438///melanin biosynthetic process+++GO:0042981///regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051591///response to cAMP+++GO:0060395///SMAD protein signal transduction+++GO:0060711///labyrinthine layer development+++GO:0060712///spongiotrophoblast layer development+++GO:0070555///response to interleukin-1+++GO:0070669///response to interleukin-2+++GO:0070670///response to interleukin-4+++GO:0070741///response to interleukin-6+++GO:0071104///response to interleukin-9+++GO:0071105///response to interleukin-11+++GO:0071107///response to parathyroid hormone+++GO:0071559///response to transforming growth factor beta" 12709 12709 'Ckb' mRNA 22511 22556 22921 902.03 891.55 974.41 622.29 662.41 640.45 922.6633333 641.7166667 17838 18527 17760 22662.66667 18041.66667 5.32E-09 -0.341768622 00330///Arginine and proline metabolism GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004111///creatine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0031625///ubiquitin protein ligase binding" GO:0021549///cerebellum development+++GO:0030644///cellular chloride ion homeostasis+++GO:0046314///phosphocreatine biosynthetic process 12715 12715 'Ckm' mRNA 1 2 3 0.04 0.08 0.13 0.18 0.26 0.27 0.083333333 0.236666667 5 7 7 2 6.333333333 0.234560962 1.643748551 00330///Arginine and proline metabolism GO:0005615///extracellular space+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004111///creatine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups" GO:0006603///phosphocreatine metabolic process+++GO:0009408///response to heat+++GO:0016310///phosphorylation+++GO:0046314///phosphocreatine biosynthetic process 12716 12716 'Ckmt1' mRNA 633 683 581 23.66 24.94 22.73 19.3 18.68 17.7 23.77666667 18.56 588 560 523 632.3333333 557 0.106211944 -0.193028021 00330///Arginine and proline metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0044289///contact site "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004111///creatine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0042802///identical protein binding" GO:0016310///phosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0043066///negative regulation of apoptotic process+++GO:0046314///phosphocreatine biosynthetic process 12721 12721 'Coro1a' mRNA 308 288 221 10.8 9.94 8.21 120.96 117.86 121.05 9.65 119.9566667 3963 3768 3838 272.3333333 3856.333333 0 3.815354889 04145///Phagosome+++05152///Tuberculosis GO:0001772///immunological synapse+++GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030670///phagocytic vesicle membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0032426///stereocilium tip+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008092///cytoskeletal protein binding+++GO:0032036///myosin heavy chain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0051015///actin filament binding GO:0001845///phagolysosome assembly+++GO:0006816///calcium ion transport+++GO:0006909///phagocytosis+++GO:0007015///actin filament organization+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0030595///leukocyte chemotaxis+++GO:0030833///regulation of actin filament polymerization+++GO:0031339///negative regulation of vesicle fusion+++GO:0031589///cell-substrate adhesion+++GO:0032796///uropod organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034097///response to cytokine+++GO:0038180///nerve growth factor signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0043029///T cell homeostasis+++GO:0043320///natural killer cell degranulation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050870///positive regulation of T cell activation+++GO:0050918///positive chemotaxis+++GO:0051126///negative regulation of actin nucleation+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0061502///early endosome to recycling endosome transport+++GO:0071353///cellular response to interleukin-4 12722 12722 'Clca3a1' mRNA 41.84 54.75 42.85 0.56 0.71 0.6 2.47 2.17 2.49 0.623333333 2.376666667 217.38 183.16 206.92 46.48 202.4866667 2.12E-19 2.134398753 04924///Renin secretion+++04972///Pancreatic secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0042589///zymogen granule membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006821///chloride transport+++GO:0071456///cellular response to hypoxia 12723 12723 'Clcn1' mRNA 22.24 10.72 17.85 0.23 0.11 0.2 0.08 0.02 0.01 0.18 0.036666667 8 2 1 16.93666667 3.666666667 0.021534822 -2.18270089 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex+++GO:0042383///sarcolemma GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0042803///protein homodimerization activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006936///muscle contraction+++GO:0019227///neuronal action potential propagation+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport 12724 12724 'Clcn2' mRNA 2524.75 2511.2 1003.36 37.26 36.58 15.71 12.02 15.87 18.24 29.85 15.37666667 936.65 1213.37 1370.33 2013.103333 1173.45 0.103381001 -0.767947064 04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0043204///perikaryon GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0030324///lung development+++GO:0032347///regulation of aldosterone biosynthetic process+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0060041///retina development in camera-type eye+++GO:0060689///cell differentiation involved in salivary gland development 12725 12725 'Clcn3' mRNA 2644 2773 2733 25.18 26.2 27.69 20.9 18.95 21.12 26.35666667 20.32333333 2506 2216 2454 2716.666667 2392 0.009635947 -0.197186816 04613///Neutrophil extracellular trap formation GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009897///external side of plasma membrane+++GO:0010008///endosome membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0042581///specific granule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0060077///inhibitory synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005524///ATP binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0030165///PDZ domain binding+++GO:0072320///volume-sensitive chloride channel activity "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006911///phagocytosis, engulfment+++GO:0008344///adult locomotory behavior+++GO:0034220///ion transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0045494///photoreceptor cell maintenance+++GO:0045794///negative regulation of cell volume+++GO:0051932///synaptic transmission, GABAergic+++GO:0055085///transmembrane transport+++GO:0070050///neuron cellular homeostasis+++GO:0097401///synaptic vesicle lumen acidification+++GO:1902476///chloride transmembrane transport+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process" 12727 12727 'Clcn4' mRNA 3563 3574 3496 42.81 41.75 44.57 31.6 31.92 32.63 43.04333333 32.05 2979 2948 2969 3544.333333 2965.333333 1.92E-05 -0.26938865 04613///Neutrophil extracellular trap formation GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0097546///ciliary base GO:0000166///nucleotide binding+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005524///ATP binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1905515///non-motile cilium assembly 12728 12728 'Clcn5' mRNA 221 259 189 1.33 1.56 1.21 3.49 3.01 3.56 1.366666667 3.353333333 663 564 656 223 627.6666667 5.08E-28 1.484379284 04613///Neutrophil extracellular trap formation GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell GO:0000166///nucleotide binding+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005524///ATP binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006897///endocytosis+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 12729 12729 'Clns1a' mRNA 1437 1555 1631 23.06 24.55 27.76 26.25 26.96 25.92 25.12333333 26.37666667 1882 1888 1800 1541 1856.666667 0.005277353 0.254489667 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex "GO:0000387///spliceosomal snRNP assembly+++GO:0006821///chloride transport+++GO:0006884///cell volume homeostasis+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0045794///negative regulation of cell volume" 12733 12733 'Clcnka' mRNA 4084 4267 4049 94.81 97.56 99.74 125.72 126.11 118.75 97.37 123.5266667 6228 6100 5695 4133.333333 6007.666667 5.14E-19 0.52752268 GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0034707///chloride channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0050878///regulation of body fluid levels+++GO:0055085///transmembrane transport+++GO:0072053///renal inner medulla development 12737 12737 'Cldn1' mRNA 30 29 20 0.51 0.48 0.36 0.94 1.6 1.36 0.45 1.3 64 107 90 26.33333333 87 2.49E-06 1.722644251 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0070160///tight junction GO:0001618///virus receptor activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007568///aging+++GO:0008065///establishment of blood-nerve barrier+++GO:0009636///response to toxic substance+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0030335///positive regulation of cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0034331///cell junction maintenance+++GO:0042538///hyperosmotic salinity response+++GO:0045216///cell-cell junction organization+++GO:0045471///response to ethanol+++GO:0046718///viral entry into host cell+++GO:0051259///protein complex oligomerization+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0061436///establishment of skin barrier+++GO:0061772///drug transport across blood-nerve barrier+++GO:0070673///response to interleukin-18+++GO:0070830///bicellular tight junction assembly+++GO:0071284///cellular response to lead ion+++GO:0071346///cellular response to interferon-gamma+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071548///response to dexamethasone+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090303///positive regulation of wound healing+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0097421///liver regeneration+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:1903545///cellular response to butyrate 12738 12738 'Cldn2' mRNA 9 9 7 0.16 0.2 0.21 2.35 2.99 3.5 0.19 2.946666667 152 188 213 8.333333333 184.3333333 7.31E-32 4.460115187 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 12739 12739 'Cldn3' mRNA 4741 5020 4502 228.3 238.66 230.01 221.63 224.34 227.44 232.3233333 224.47 5283 5216 5243 4754.333333 5247.333333 0.023742523 0.131870261 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043296///apical junction complex+++GO:0070160///tight junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003382///epithelial cell morphogenesis+++GO:0007155///cell adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014045///establishment of endothelial blood-brain barrier+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0022604///regulation of cell morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0034331///cell junction maintenance+++GO:0045471///response to ethanol+++GO:0061045///negative regulation of wound healing+++GO:0070830///bicellular tight junction assembly+++GO:0090303///positive regulation of wound healing+++GO:0090559///regulation of membrane permeability+++GO:1901890///positive regulation of cell junction assembly+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:1905050///positive regulation of metallopeptidase activity 12740 12740 'Cldn4' mRNA 983 969 817 31.24 30.35 27.55 61.66 61.11 57.55 29.71333333 60.10666667 2230 2157 2014 923 2133.666667 1.39E-51 1.199809899 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0034707///chloride channel complex+++GO:0070160///tight junction GO:0005198///structural molecule activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007155///cell adhesion+++GO:0007565///female pregnancy+++GO:0007623///circadian rhythm+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0022604///regulation of cell morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0032570///response to progesterone+++GO:0061436///establishment of skin barrier+++GO:0070293///renal absorption+++GO:0070830///bicellular tight junction assembly+++GO:0090303///positive regulation of wound healing+++GO:1905050///positive regulation of metallopeptidase activity 12741 12741 'Cldn5' mRNA 2803 2664 2653 118.03 110.68 118.52 119.09 110.9 108.3 115.7433333 112.7633333 3248 2951 2857 2706.666667 3018.666667 0.05342705 0.144402339 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0033270///paranode region of axon+++GO:0043220///Schmidt-Lanterman incisure+++GO:0070160///tight junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0016525///negative regulation of angiogenesis+++GO:0030336///negative regulation of cell migration+++GO:0032092///positive regulation of protein binding+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042552///myelination+++GO:0043116///negative regulation of vascular permeability+++GO:0045471///response to ethanol+++GO:0070830///bicellular tight junction assembly+++GO:0098609///cell-cell adhesion+++GO:0120192///tight junction assembly+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:1990963///establishment of blood-retinal barrier 12745 12745 'Clgn' mRNA 8 0 3 0.11 0 0.04 0.04 0.02 0.05 0.05 0.036666667 3 2 3 3.666666667 2.666666667 0.819903519 -0.474612147 GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0030154///cell differentiation+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0051321///meiotic cell cycle+++GO:0065003///protein-containing complex assembly 12747 12747 'Clk1' mRNA 3554 3389 3424 111.71 104.98 114.17 81.93 77.01 81.86 110.2866667 80.26666667 2996 2749 2897 3455.666667 2880.666667 3.54E-05 -0.275633807 05134///Legionellosis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation 12748 12748 'Clk2' mRNA 258.32 221.58 185.2 6.25 5.28 4.75 5.32 3.8 5.19 5.426666667 4.77 253.12 176.58 239 221.7 222.9 0.998591786 -0.001357345 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032526///response to retinoic acid+++GO:0043484///regulation of RNA splicing+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046777///protein autophosphorylation 12750 12750 'Clk4' mRNA 1256 1344 1326 35.87 37.5 40.12 36.44 36.62 36.98 37.83 36.68 1469 1428 1433 1308.666667 1443.333333 0.162572192 0.128431247 05134///Legionellosis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation 12751 12751 'Tpp1' mRNA 3157 3368 3270 53.89 57.08 59.46 99.24 103.85 103.76 56.81 102.2833333 6853 6856 6717 3265 6808.666667 8.41E-69 1.04795721 04142///Lysosome GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0042470///melanosome+++GO:0045121///membrane raft+++GO:0055037///recycling endosome GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008240///tripeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0035727///lysophosphatidic acid binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0120146///sulfatide binding "GO:0006508///proteolysis+++GO:0007040///lysosome organization+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0030855///epithelial cell differentiation+++GO:0043171///peptide catabolic process+++GO:0045453///bone resorption+++GO:0050885///neuromuscular process controlling balance+++GO:0070198///protein localization to chromosome, telomeric region+++GO:1905146///lysosomal protein catabolic process" 12752 12752 'Cln3' mRNA 1114 1103 1108 32.11 32.03 33.98 38.63 35.85 36.2 32.70666667 36.89333333 1492 1355.25 1356 1108.333333 1401.083333 1.40E-04 0.324790135 04142///Lysosome GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005773///vacuole+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0043005///neuron projection+++GO:0044754///autolysosome+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0051861///glycolipid binding+++GO:0120146///sulfatide binding "GO:0001508///action potential+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006865///amino acid transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007040///lysosome organization+++GO:0007042///lysosomal lumen acidification+++GO:0007611///learning or memory+++GO:0008306///associative learning+++GO:0009992///cellular water homeostasis+++GO:0010468///regulation of gene expression+++GO:0010506///regulation of autophagy+++GO:0010762///regulation of fibroblast migration+++GO:0015809///arginine transport+++GO:0016236///macroautophagy+++GO:0016243///regulation of autophagosome size+++GO:0016477///cell migration+++GO:0016485///protein processing+++GO:0030036///actin cytoskeleton organization+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035752///lysosomal lumen pH elevation+++GO:0036359///renal potassium excretion+++GO:0042133///neurotransmitter metabolic process+++GO:0042987///amyloid precursor protein catabolic process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044857///plasma membrane raft organization+++GO:0045861///negative regulation of proteolysis+++GO:0046474///glycerophospholipid biosynthetic process+++GO:0046836///glycolipid transport+++GO:0047496///vesicle transport along microtubule+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048549///positive regulation of pinocytosis+++GO:0050885///neuromuscular process controlling balance+++GO:0051453///regulation of intracellular pH+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051489///regulation of filopodium assembly+++GO:0051493///regulation of cytoskeleton organization+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0061024///membrane organization+++GO:0061909///autophagosome-lysosome fusion+++GO:0070613///regulation of protein processing+++GO:0072657///protein localization to membrane+++GO:0072659///protein localization to plasma membrane+++GO:0090160///Golgi to lysosome transport+++GO:0090384///phagosome-lysosome docking+++GO:0090385///phagosome-lysosome fusion+++GO:0097352///autophagosome maturation+++GO:0106049///regulation of cellular response to osmotic stress+++GO:1900079///regulation of arginine biosynthetic process+++GO:1901096///regulation of autophagosome maturation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903826///arginine transmembrane transport+++GO:1905146///lysosomal protein catabolic process+++GO:1905162///regulation of phagosome maturation+++GO:1905244///regulation of modification of synaptic structure+++GO:2001288///positive regulation of caveolin-mediated endocytosis" 12753 12753 'Clock' mRNA 975 987 913 5.33 5.28 5.23 4.58 3.53 3.66 5.28 3.923333333 975 720 752 958.3333333 815.6666667 0.038526507 -0.246251883 04710///Circadian rhythm+++04711///Circadian rhythm - fly+++04728///Dopaminergic synapse GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005694///chromosome+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0033391///chromatoid body+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990513///CLOCK-BMAL transcription complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000077///DNA damage checkpoint+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006473///protein acetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007623///circadian rhythm+++GO:0016573///histone acetylation+++GO:0032922///circadian regulation of gene expression+++GO:0042634///regulation of hair cycle+++GO:0042752///regulation of circadian rhythm+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050729///positive regulation of inflammatory response+++GO:0050796///regulation of insulin secretion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051775///response to redox state+++GO:0071479///cellular response to ionizing radiation+++GO:2000074///regulation of type B pancreatic cell development+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway" 12757 12757 'Clta' mRNA 2022 1966 1791 115.31 110.29 107.31 208.85 204.32 212.33 110.97 208.5 4125 3979 4082 1926.333333 4062 1.42E-70 1.065972405 04142///Lysosome+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease+++05100///Bacterial invasion of epithelial cells GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030118///clathrin coat+++GO:0030125///clathrin vesicle coat+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0030132///clathrin coat of coated pit+++GO:0030136///clathrin-coated vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0071439///clathrin complex+++GO:0098835///presynaptic endocytic zone membrane+++GO:0098843///postsynaptic endocytic zone+++GO:0098978///glutamatergic synapse+++GO:0099631///postsynaptic endocytic zone cytoplasmic component GO:0005198///structural molecule activity+++GO:0032050///clathrin heavy chain binding+++GO:0042277///peptide binding+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007049///cell cycle+++GO:0016192///vesicle-mediated transport+++GO:0048268///clathrin coat assembly+++GO:0051301///cell division+++GO:0072583///clathrin-dependent endocytosis 12759 12759 'Clu' mRNA 29003 30180 27891 919.45 943.39 937.68 2042.28 1874 1986.73 933.5066667 1967.67 73971 66236 69609 29024.66667 69938.66667 9.69E-161 1.256739985 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0034366///spherical high-density lipoprotein particle+++GO:0042583///chromaffin granule+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix+++GO:0071944///cell periphery+++GO:0097418///neurofibrillary tangle+++GO:0097440///apical dendrite+++GO:0099020///perinuclear endoplasmic reticulum lumen GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0048156///tau protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0000902///cell morphogenesis+++GO:0001774///microglial cell activation+++GO:0002434///immune complex clearance+++GO:0008284///positive regulation of cell proliferation+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0017038///protein import+++GO:0031018///endocrine pancreas development+++GO:0031333///negative regulation of protein complex assembly+++GO:0031334///positive regulation of protein complex assembly+++GO:0032286///central nervous system myelin maintenance+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042127///regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045597///positive regulation of cell differentiation+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048812///neuron projection morphogenesis+++GO:0050821///protein stabilization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051788///response to misfolded protein+++GO:0060548///negative regulation of cell death+++GO:0061077///chaperone-mediated protein folding+++GO:0061518///microglial cell proliferation+++GO:0061740///protein targeting to lysosome involved in chaperone-mediated autophagy+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1900221///regulation of amyloid-beta clearance+++GO:1901214///regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902847///regulation of neuronal signal transduction+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:1902998///positive regulation of neurofibrillary tangle assembly+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1905892///negative regulation of cellular response to thapsigargin+++GO:1905895///negative regulation of cellular response to tunicamycin+++GO:1905907///negative regulation of amyloid fibril formation+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 12763 12763 'Cmah' mRNA 966.8 958.68 808.49 5.47 5.32 4.84 3.24 3.04 3.29 5.21 3.19 657.59 613.56 662.2 911.3233333 644.45 2.69E-07 -0.50892324 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0016020///membrane "GO:0016491///oxidoreductase activity+++GO:0030338///CMP-N-acetylneuraminate monooxygenase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006054///N-acetylneuraminate metabolic process+++GO:0030111///regulation of Wnt signaling pathway+++GO:0046381///CMP-N-acetylneuraminate metabolic process 12764 12764 'Cmas' mRNA 189 181 147 6.28 5.94 5.19 8.07 6.08 7.53 5.803333333 7.226666667 277 206 250 172.3333333 244.3333333 0.010084049 0.493497434 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005634///nucleus GO:0008781///N-acylneuraminate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0006054///N-acetylneuraminate metabolic process+++GO:0006055///CMP-N-acetylneuraminate biosynthetic process 12765 12765 'Cxcr2' mRNA 124.58 102.24 107.3 2.27 1.84 2.07 1.64 1.95 2.29 2.06 1.96 103.81 120.32 139.8 111.3733333 121.31 0.738955171 0.110382323 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05163///Human cytomegalovirus infection GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042629///mast cell granule+++GO:0072686///mitotic spindle GO:0004918///interleukin-8 receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0019959///interleukin-8 binding GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0019722///calcium-mediated signaling+++GO:0030593///neutrophil chemotaxis+++GO:0030901///midbrain development+++GO:0031623///receptor internalization+++GO:0033030///negative regulation of neutrophil apoptotic process+++GO:0038112///interleukin-8-mediated signaling pathway+++GO:0042119///neutrophil activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043117///positive regulation of vascular permeability+++GO:0045766///positive regulation of angiogenesis+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0072173///metanephric tubule morphogenesis+++GO:0090023///positive regulation of neutrophil chemotaxis 12766 12766 'Cxcr3' mRNA 5 13 17 0.18 0.47 0.66 2.25 2.5 2.71 0.436666667 2.486666667 71 77 83 11.66666667 77 1.08E-09 2.703988223 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019956///chemokine binding+++GO:0019957///C-C chemokine binding+++GO:0019958///C-X-C chemokine binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002685///regulation of leukocyte migration+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010818///T cell chemotaxis+++GO:0016525///negative regulation of angiogenesis+++GO:0019722///calcium-mediated signaling+++GO:0030155///regulation of cell adhesion+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050921///positive regulation of chemotaxis+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071954///chemokine (C-C motif) ligand 11 production+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900119///positive regulation of execution phase of apoptosis 12767 12767 'Cxcr4' mRNA 64 46 46 2.03 1.44 1.55 3.49 3.28 3.51 1.673333333 3.426666667 127 116 123 52 122 8.72E-06 1.219854203 04020///Calcium signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04670///Leukocyte transendothelial migration+++04672///Intestinal immune network for IgA production+++04810///Regulation of actin cytoskeleton+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex GO:0003779///actin binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019955///cytokine binding+++GO:0019957///C-C chemokine binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032027///myosin light chain binding+++GO:0036094///small molecule binding+++GO:0038147///C-X-C motif chemokine 12 receptor activity+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001667///ameboidal-type cell migration+++GO:0001764///neuron migration+++GO:0001822///kidney development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002064///epithelial cell development+++GO:0003281///ventricular septum development+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007281///germ cell development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008038///neuron recognition+++GO:0008045///motor neuron axon guidance+++GO:0008354///germ cell migration+++GO:0009887///animal organ morphogenesis+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0016477///cell migration+++GO:0019722///calcium-mediated signaling+++GO:0022008///neurogenesis+++GO:0022029///telencephalon cell migration+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0035470///positive regulation of vascular wound healing+++GO:0035690///cellular response to drug+++GO:0035701///hematopoietic stem cell migration+++GO:0035904///aorta development+++GO:0038160///CXCL12-activated CXCR4 signaling pathway+++GO:0042098///T cell proliferation+++GO:0043067///regulation of programmed cell death+++GO:0043217///myelin maintenance+++GO:0043278///response to morphine+++GO:0045446///endothelial cell differentiation+++GO:0048699///generation of neurons+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050769///positive regulation of neurogenesis+++GO:0050792///regulation of viral process+++GO:0050920///regulation of chemotaxis+++GO:0050921///positive regulation of chemotaxis+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051924///regulation of calcium ion transport+++GO:0060048///cardiac muscle contraction+++GO:0060326///cell chemotaxis+++GO:0061154///endothelial tube morphogenesis+++GO:0061351///neural precursor cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071345///cellular response to cytokine stimulus+++GO:0090280///positive regulation of calcium ion import+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903861///positive regulation of dendrite extension+++GO:1905322///positive regulation of mesenchymal stem cell migration+++GO:1990478///response to ultrasound+++GO:2000448///positive regulation of macrophage migration inhibitory factor signaling pathway 12768 12768 'Ccr1' mRNA 92 128 129 1.79 2.45 2.67 25.18 23.86 22.9 2.303333333 23.98 1487 1376 1309 116.3333333 1390.666667 6.92E-166 3.56552261 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0035717///chemokine (C-C motif) ligand 7 binding+++GO:0071791///chemokine (C-C motif) ligand 5 binding GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006887///exocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0010629///negative regulation of gene expression+++GO:0019722///calcium-mediated signaling+++GO:0021549///cerebellum development+++GO:0030099///myeloid cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030502///negative regulation of bone mineralization+++GO:0030595///leukocyte chemotaxis+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045824///negative regulation of innate immune response+++GO:0051928///positive regulation of calcium ion transport+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090026///positive regulation of monocyte chemotaxis 12769 12769 'Ccr9' mRNA 29 31 15 0.36 0.38 0.2 0.26 0.2 0.38 0.313333333 0.28 24 18 34 25 25.33333333 0.984428121 0.018784046 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04672///Intestinal immune network for IgA production GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding "GO:0002305///CD8-positive, gamma-delta intraepithelial T cell differentiation+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway" 12771 12771 'Ccr3' mRNA 3 1 3 0.05 0.02 0.05 0.1 0.1 0.16 0.04 0.12 7 7 11 2.333333333 8.333333333 0.134844047 1.81767732 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05203///Viral carcinogenesis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002551///mast cell chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0035476///angioblast cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0048245///eosinophil chemotaxis+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070371///ERK1 and ERK2 cascade 12772 12772 'Ccr2' mRNA 47 48 54 0.71 0.7 0.91 15.85 14.24 16.34 0.773333333 15.47666667 1146.99 1005.47 1159.95 49.66666667 1104.136667 1.61E-173 4.460489566 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019955///cytokine binding+++GO:0019957///C-C chemokine binding+++GO:0031727///CCR2 chemokine receptor binding+++GO:0035715///chemokine (C-C motif) ligand 2 binding+++GO:0035716///chemokine (C-C motif) ligand 12 binding+++GO:0035717///chemokine (C-C motif) ligand 7 binding+++GO:0071791///chemokine (C-C motif) ligand 5 binding "GO:0001525///angiogenesis+++GO:0001974///blood vessel remodeling+++GO:0002246///wound healing involved in inflammatory response+++GO:0002548///monocyte chemotaxis+++GO:0002724///regulation of T cell cytokine production+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0002829///negative regulation of type 2 immune response+++GO:0006874///cellular calcium ion homeostasis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006959///humoral immune response+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0019725///cellular homeostasis+++GO:0030097///hemopoiesis+++GO:0030334///regulation of cell migration+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035696///monocyte extravasation+++GO:0035705///T-helper 17 cell chemotaxis+++GO:0043277///apoptotic cell clearance+++GO:0043310///negative regulation of eosinophil degranulation+++GO:0045580///regulation of T cell differentiation+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050870///positive regulation of T cell activation+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060326///cell chemotaxis+++GO:0061756///leukocyte adhesion to vascular endothelial cell+++GO:0070098///chemokine-mediated signaling pathway+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090265///positive regulation of immune complex clearance by monocytes and macrophages+++GO:0090594///inflammatory response to wounding+++GO:0097350///neutrophil clearance+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1905517///macrophage migration+++GO:2000412///positive regulation of thymocyte migration+++GO:2000439///positive regulation of monocyte extravasation+++GO:2000451///positive regulation of CD8-positive, alpha-beta T cell extravasation+++GO:2000464///positive regulation of astrocyte chemotaxis+++GO:2000473///positive regulation of hematopoietic stem cell migration" 12773 12773 'Ccr4' mRNA 2 1 0 0.07 0.02 0 0.03 0 0 0.03 0.01 1 0 0 1 0.333333333 0.735493953 -1.462200403 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection+++05203///Viral carcinogenesis GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0001764///neuron migration+++GO:0002507///tolerance induction+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009314///response to radiation+++GO:0009617///response to bacterium+++GO:0019722///calcium-mediated signaling+++GO:0046677///response to antibiotic+++GO:0048872///homeostasis of number of cells+++GO:0050927///positive regulation of positive chemotaxis+++GO:0060326///cell chemotaxis 12774 12774 'Ccr5' mRNA 88 95 75 1.6 1.7 1.38 16.1 14.8 17.3 1.56 16.06666667 1036.01 921.53 1064.05 86 1007.196667 7.46E-143 3.539566035 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04144///Endocytosis+++05145///Toxoplasmosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003779///actin binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0019901///protein kinase binding+++GO:0019957///C-C chemokine binding+++GO:0042802///identical protein binding+++GO:0071791///chemokine (C-C motif) ligand 5 binding GO:0006816///calcium ion transport+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0010628///positive regulation of gene expression+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0019722///calcium-mediated signaling+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0031622///positive regulation of fever generation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0045666///positive regulation of neuron differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0060139///positive regulation of apoptotic process by virus+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070723///response to cholesterol+++GO:0070997///neuron death+++GO:2000110///negative regulation of macrophage apoptotic process+++GO:2000178///negative regulation of neural precursor cell proliferation 12775 12775 'Ccr7' mRNA 2 3 2 0.06 0.09 0.06 2.23 2.09 2.16 0.07 2.16 89 81 83 2.333333333 84.33333333 2.36E-15 5.165042867 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0035757///chemokine (C-C motif) ligand 19 binding+++GO:0035758///chemokine (C-C motif) ligand 21 binding+++GO:0038117///C-C motif chemokine 19 receptor activity+++GO:0038121///C-C motif chemokine 21 receptor activity GO:0001768///establishment of T cell polarity+++GO:0002408///myeloid dendritic cell chemotaxis+++GO:0002518///lymphocyte chemotaxis across high endothelial venule+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0002649///regulation of tolerance induction to self antigen+++GO:0002885///positive regulation of hypersensitivity+++GO:0002922///positive regulation of humoral immune response+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007257///activation of JUN kinase activity+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0019722///calcium-mediated signaling+++GO:0030036///actin cytoskeleton organization+++GO:0032496///response to lipopolysaccharide+++GO:0032649///regulation of interferon-gamma production+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034695///response to prostaglandin E+++GO:0038115///chemokine (C-C motif) ligand 19 signaling pathway+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045060///negative thymic T cell selection+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048535///lymph node development+++GO:0048872///homeostasis of number of cells+++GO:0050766///positive regulation of phagocytosis+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051491///positive regulation of filopodium assembly+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071345///cellular response to cytokine stimulus+++GO:0071731///response to nitric oxide+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0097022///lymphocyte migration into lymph node+++GO:0097029///mature conventional dendritic cell differentiation+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:2000147///positive regulation of cell motility+++GO:2000412///positive regulation of thymocyte migration+++GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:2000522///positive regulation of immunological synapse formation+++GO:2000525///positive regulation of T cell costimulation+++GO:2000526///positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation+++GO:2000547///regulation of dendritic cell dendrite assembly 12776 12776 'Ccr8' mRNA 0 1 0 0 0.05 0 0.19 0 0 0.016666667 0.063333333 4 0 0 0.333333333 1.333333333 0.654980456 1.854011049 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection+++05203///Viral carcinogenesis GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 12777 12777 'Ccr10' mRNA 18 15 13 0.6 0.5 0.46 0.7 0.81 0.36 0.52 0.623333333 24 27 12 15.33333333 21 0.5447461 0.445426937 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04672///Intestinal immune network for IgA production GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 12778 12778 'Ackr3' mRNA 1314 1351 1238 36.62 37.03 36.57 24.12 21.57 24.61 36.74 23.43333333 996 869 983 1301 949.3333333 6.21E-08 -0.466267602 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0004930///G protein-coupled receptor activity+++GO:0005044///scavenger receptor activity+++GO:0015026///coreceptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019956///chemokine binding+++GO:0019957///C-C chemokine binding+++GO:0019958///C-X-C chemokine binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0019722///calcium-mediated signaling+++GO:0031623///receptor internalization+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1905322///positive regulation of mesenchymal stem cell migration 12780 12780 'Abcc2' mRNA 3 3 4 0.03 0.03 0.04 0 0 0.04 0.033333333 0.013333333 0 0 5 3.333333333 1.666666667 0.650176154 -1.013782033 01523///Antifolate resistance+++01524///Platinum drug resistance+++02010///ABC transporters+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0046581///intercellular canaliculus+++GO:0046691///intracellular canaliculus "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015127///bilirubin transmembrane transporter activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0019904///protein domain specific binding+++GO:0022857///transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity" GO:0006855///drug transmembrane transport+++GO:0006954///inflammatory response+++GO:0006979///response to oxidative stress+++GO:0007565///female pregnancy+++GO:0009408///response to heat+++GO:0009410///response to xenobiotic stimulus+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0015694///mercury ion transport+++GO:0015711///organic anion transport+++GO:0015721///bile acid and bile salt transport+++GO:0015722///canalicular bile acid transport+++GO:0015723///bilirubin transport+++GO:0015732///prostaglandin transport+++GO:0016999///antibiotic metabolic process+++GO:0030644///cellular chloride ion homeostasis+++GO:0031427///response to methotrexate+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0033762///response to glucagon+++GO:0035690///cellular response to drug+++GO:0038183///bile acid signaling pathway+++GO:0042178///xenobiotic catabolic process+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0046618///drug export+++GO:0046685///response to arsenic-containing substance+++GO:0048545///response to steroid hormone+++GO:0050787///detoxification of mercury ion+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:0070633///transepithelial transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071716///leukotriene transport+++GO:0097327///response to antineoplastic agent+++GO:0120188///regulation of bile acid secretion+++GO:1901086///benzylpenicillin metabolic process+++GO:1904486///response to 17alpha-ethynylestradiol+++GO:1990961///drug transmembrane export+++GO:1990962///drug transport across blood-brain barrier 12785 12785 'Cnbp' mRNA 13245 13415 13119 344.56 343.72 362.01 289.12 297.84 293.14 350.0966667 293.3666667 12777 12851 12538 13259.66667 12722 0.236097812 -0.071866243 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0045182///translation regulator activity+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071919///G-quadruplex DNA formation+++GO:2000767///positive regulation of cytoplasmic translation" 12788 12788 'Cnga1' mRNA 4 3 3 0.08 0.06 0.07 0.02 0 0 0.07 0.006666667 1 0 0 3.333333333 0.333333333 0.154258236 -3.227860432 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017071///intracellular cyclic nucleotide activated cation channel complex+++GO:0042622///photoreceptor outer segment membrane+++GO:0043195///terminal bouton GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005221///intracellular cyclic nucleotide activated cation channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0030553///cGMP binding GO:0006811///ion transport+++GO:0007601///visual perception+++GO:0050896///response to stimulus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051899///membrane depolarization+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 12789 12789 'Cnga2' mRNA 98 133 106 1.75 2.35 2.01 0.12 0.2 0.18 2.036666667 0.166666667 8 13 11 112.3333333 10.66666667 2.11E-18 -3.404529927 04024///cAMP signaling pathway+++04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017071///intracellular cyclic nucleotide activated cation channel complex+++GO:0043204///perikaryon+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005516///calmodulin binding+++GO:0030552///cAMP binding+++GO:0030553///cGMP binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007608///sensory perception of smell+++GO:0034220///ion transmembrane transport+++GO:0050896///response to stimulus+++GO:0051899///membrane depolarization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098655///cation transmembrane transport 12790 12790 'Cnga3' mRNA 2 4 5 0.03 0.06 0.08 0.03 0.01 0.06 0.056666667 0.033333333 2 1 4 3.666666667 2.333333333 0.720620081 -0.675335136 04024///cAMP signaling pathway+++04740///Olfactory transduction GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043204///perikaryon+++GO:0097386///glial cell projection+++GO:1902495///transmembrane transporter complex GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005221///intracellular cyclic nucleotide activated cation channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030553///cGMP binding GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007601///visual perception+++GO:0031960///response to corticosteroid+++GO:0032026///response to magnesium ion+++GO:0034220///ion transmembrane transport+++GO:0046549///retinal cone cell development+++GO:0050896///response to stimulus+++GO:0051591///response to cAMP+++GO:0055085///transmembrane transport+++GO:0098659///inorganic cation import across plasma membrane 12793 12793 'Cnih1' mRNA 1571 1653 1494 62.66 65.03 63.22 74.65 72.6 72.93 63.63666667 73.39333333 2150 2040 2032 1572.666667 2074 2.77E-08 0.388177494 GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016192///vesicle-mediated transport 12794 12794 'Cnih2' mRNA 39 35 28 1.75 1.55 1.33 1.13 0.48 0.61 1.543333333 0.74 29 12 15 34 18.66666667 0.111961255 -0.879011734 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032281///AMPA glutamate receptor complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0016247///channel regulator activity "GO:0016192///vesicle-mediated transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0051668///localization within membrane+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:1902684///negative regulation of receptor localization to synapse+++GO:1903743///negative regulation of anterograde synaptic vesicle transport+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity" 12795 12795 'Plk3' mRNA 83 86 37 2.04 1.99 0.95 4.01 6.58 7.14 1.66 5.91 195 314 335 68.66666667 281.3333333 1.33E-13 2.041296518 04068///FoxO signaling pathway+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis GO:0000785///chromatin+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0000302///response to reactive oxygen species+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006970///response to osmotic stress+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0009314///response to radiation+++GO:0016310///phosphorylation+++GO:0031122///cytoplasmic microtubule organization+++GO:0032465///regulation of cytokinesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0044819///mitotic G1/S transition checkpoint+++GO:0051302///regulation of cell division+++GO:0090166///Golgi disassembly+++GO:0090316///positive regulation of intracellular protein transport+++GO:1904716///positive regulation of chaperone-mediated autophagy+++GO:2000777///positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia 12796 12796 'Camp' mRNA 45 33 43 5.75 4.2 5.83 7.28 7.37 7.55 5.26 7.4 65 64 65 40.33333333 64.66666667 0.068964922 0.666274961 04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04970///Salivary secretion+++05150///Staphylococcus aureus infection+++05152///Tuberculosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0042581///specific granule+++GO:0042995///cell projection GO:0001530///lipopolysaccharide binding GO:0001878///response to yeast+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002227///innate immune response in mucosa+++GO:0002544///chronic inflammatory response+++GO:0006952///defense response+++GO:0008284///positive regulation of cell proliferation+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0032757///positive regulation of interleukin-8 production+++GO:0035821///modification of morphology or physiology of other organism+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051838///cytolysis by host of symbiont cells+++GO:0051873///killing by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 12797 12797 'Cnn1' mRNA 44 30 41 1.7 1.09 1.6 0.96 0.83 0.88 1.463333333 0.89 29 27 26 38.33333333 27.33333333 0.308769496 -0.504086513 GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0005516///calmodulin binding GO:0031032///actomyosin structure organization+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation 12798 12798 'Cnn2' mRNA 1316 1334 1233 42.62 42.58 42.36 73.79 74.85 77.22 42.52 75.28666667 2619 2593 2652 1294.333333 2621.333333 1.44E-50 1.007366203 GO:0001725///stress fiber+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0005516///calmodulin binding GO:0007010///cytoskeleton organization+++GO:0010628///positive regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030336///negative regulation of cell migration+++GO:0031032///actomyosin structure organization+++GO:0032970///regulation of actin filament-based process+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0050765///negative regulation of phagocytosis+++GO:0071260///cellular response to mechanical stimulus 12799 12799 'Cnp' mRNA 9471 10119 9655 217.4 228.9 235.75 176.66 176.17 181.22 227.35 178.0166667 8738 8532 8684 9748.333333 8651.333333 0.001165135 -0.184446078 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0031143///pseudopodium+++GO:0035748///myelin sheath abaxonal region+++GO:0035749///myelin sheath adaxonal region+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm "GO:0003723///RNA binding+++GO:0004113///2',3'-cyclic-nucleotide 3'-phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0030551///cyclic nucleotide binding" GO:0000226///microtubule cytoskeleton organization+++GO:0007409///axonogenesis+++GO:0007568///aging+++GO:0008344///adult locomotory behavior+++GO:0009214///cyclic nucleotide catabolic process+++GO:0009636///response to toxic substance+++GO:0030900///forebrain development+++GO:0032496///response to lipopolysaccharide+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048709///oligodendrocyte differentiation 12801 12801 'Cnr1' mRNA 20 21 20 0.19 0.2 0.21 0.27 0.05 0.15 0.2 0.156666667 32 6 17 20.33333333 18.33333333 0.854872748 -0.172732103 04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0032592///integral component of mitochondrial membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004949///cannabinoid receptor activity+++GO:0042802///identical protein binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels "GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007413///axonal fasciculation+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0010976///positive regulation of neuron projection development+++GO:0014063///negative regulation of serotonin secretion+++GO:0019216///regulation of lipid metabolic process+++GO:0019222///regulation of metabolic process+++GO:0019233///sensory perception of pain+++GO:0031622///positive regulation of fever generation+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0032496///response to lipopolysaccharide+++GO:0033004///negative regulation of mast cell activation+++GO:0033602///negative regulation of dopamine secretion+++GO:0035094///response to nicotine+++GO:0038171///cannabinoid signaling pathway+++GO:0042220///response to cocaine+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043271///negative regulation of ion transport+++GO:0043278///response to morphine+++GO:0045471///response to ethanol+++GO:0045759///negative regulation of action potential+++GO:0045776///negative regulation of blood pressure+++GO:0045777///positive regulation of blood pressure+++GO:0050796///regulation of insulin secretion+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060135///maternal process involved in female pregnancy+++GO:0060259///regulation of feeding behavior+++GO:0060405///regulation of penile erection+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission" 12802 12802 'Cnr2' mRNA 20.37 28.39 16.63 0.28 0.38 0.24 2.49 2.01 2.05 0.3 2.183333333 215.35 168.22 168.88 21.79666667 184.15 5.81E-26 3.096798784 04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0004930///G protein-coupled receptor activity+++GO:0004949///cannabinoid receptor activity "GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0019233///sensory perception of pain+++GO:0030595///leukocyte chemotaxis+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032496///response to lipopolysaccharide+++GO:0033004///negative regulation of mast cell activation+++GO:0038171///cannabinoid signaling pathway+++GO:0045759///negative regulation of action potential+++GO:0050728///negative regulation of inflammatory response+++GO:0051001///negative regulation of nitric-oxide synthase activity" 12803 12803 'Cntf' mRNA 917 995 991 46.7 50.04 53.55 28.93 30.44 29.28 50.09666667 29.55 652 669 638 967.6666667 653 9.48E-09 -0.580288328 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0032838///plasma membrane bounded cell projection cytoplasm+++GO:0043025///neuronal cell body GO:0005125///cytokine activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005138///interleukin-6 receptor binding+++GO:0008083///growth factor activity+++GO:0044877///protein-containing complex binding GO:0007259///JAK-STAT cascade+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0046668///regulation of retinal cell programmed cell death+++GO:0046887///positive regulation of hormone secretion+++GO:0048143///astrocyte activation+++GO:0048644///muscle organ morphogenesis+++GO:0048666///neuron development+++GO:0048680///positive regulation of axon regeneration+++GO:0048691///positive regulation of axon extension involved in regeneration+++GO:0060075///regulation of resting membrane potential+++GO:0060081///membrane hyperpolarization+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:1901215///negative regulation of neuron death 12804 12804 'Cntfr' mRNA 163 160.51 54 4.54 4.44 1.55 0.95 1.41 1.24 3.51 1.2 40 55 49 125.8366667 48 2.11E-04 -1.377390669 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane+++GO:0043235///receptor complex+++GO:0070110///ciliary neurotrophic factor receptor complex+++GO:0097059///CNTFR-CLCF1 complex GO:0004896///cytokine receptor activity+++GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019955///cytokine binding GO:0001967///suckling behavior+++GO:0003360///brainstem development+++GO:0007548///sex differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0060538///skeletal muscle organ development+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway 12805 12805 'Cntn1' mRNA 5764 5950 5718 50.37 51.24 52.86 23.11 20.35 20.82 51.49 21.42666667 3105 2625.07 2675.93 5810.666667 2802 9.09E-59 -1.066005043 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0099025///anchored component of postsynaptic membrane+++GO:0099026///anchored component of presynaptic membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007626///locomotory behavior+++GO:0010628///positive regulation of gene expression+++GO:0010765///positive regulation of sodium ion transport+++GO:0010976///positive regulation of neuron projection development+++GO:0021549///cerebellum development+++GO:0031175///neuron projection development+++GO:0032289///central nervous system myelin formation+++GO:0042552///myelination+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0098609///cell-cell adhesion 12807 12807 'Hps3' mRNA 346.06 392.04 354.14 5.28 5.82 5.54 9.56 8.86 9.21 5.546666667 9.21 727 674 686.12 364.08 695.7066667 3.35E-16 0.922810879 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031084///BLOC-2 complex GO:0006996///organelle organization+++GO:0043473///pigmentation 12808 12808 'Cobl' mRNA 336 289 247 3.17 2.57 2.75 2.39 2.26 2.34 2.83 2.33 293 271 286 290.6666667 283.3333333 0.843493863 -0.045385384 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:1990357///terminal web GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding GO:0000578///embryonic axis specification+++GO:0001757///somite specification+++GO:0001843///neural tube closure+++GO:0001889///liver development+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030903///notochord development+++GO:0033504///floor plate development+++GO:0048565///digestive tract development+++GO:0048669///collateral sprouting in absence of injury+++GO:0051639///actin filament network formation+++GO:0051764///actin crosslink formation+++GO:1900006///positive regulation of dendrite development+++GO:1900029///positive regulation of ruffle assembly 12810 12810 'Coch' mRNA 173122 179674 172699 3874.22 3957.66 4097.8 3742.84 3542.77 3674.87 3976.56 3653.493333 192545 178078 183065 175165 184562.6667 0.259206129 0.062592513 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0005518///collagen binding GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0042742///defense response to bacterium+++GO:0045089///positive regulation of innate immune response 12812 12812 'Coil' mRNA 362 391 381 7.71 8.2 8.61 5.31 5.5 4.95 8.173333333 5.253333333 287 290 259 378 278.6666667 0.002099755 -0.452323429 GO:0001650///fibrillar center+++GO:0001674///female germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0015030///Cajal body+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0015036///disulfide oxidoreductase activity+++GO:0030619///U1 snRNA binding+++GO:0030620///U2 snRNA binding+++GO:0042802///identical protein binding GO:0000387///spliceosomal snRNP assembly 12813 12813 'Col10a1' mRNA 32 43 27 0.56 0.74 0.5 0.52 0.62 0.53 0.6 0.556666667 34 40 34 34 36 0.883400775 0.078465299 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005938///cell cortex+++GO:0031012///extracellular matrix+++GO:0043235///receptor complex+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046872///metal ion binding GO:0001958///endochondral ossification+++GO:0030198///extracellular matrix organization+++GO:0051216///cartilage development 12814 12814 'Col11a1' mRNA 1873 1862 1792 13.26 13.52 13.9 8.2 7.24 8.15 13.56 7.863333333 1311 1095 1241 1842.333333 1215.666667 3.39E-14 -0.612728641 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005592///collagen type XI trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046872///metal ion binding+++GO:1904399///heparan sulfate binding GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0002063///chondrocyte development+++GO:0003007///heart morphogenesis+++GO:0006029///proteoglycan metabolic process+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0035987///endodermal cell differentiation+++GO:0035989///tendon development+++GO:0042472///inner ear morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0051216///cartilage development+++GO:0055010///ventricular cardiac muscle tissue morphogenesis 12815 12815 'Col11a2' mRNA 15053 14851 13932 134.51 131.25 134.73 72.45 65.05 64.87 133.4966667 67.45666667 9277 8015 8042 14612 8444.666667 1.83E-45 -0.803499204 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001894///tissue homeostasis+++GO:0002062///chondrocyte differentiation+++GO:0007605///sensory perception of sound+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0048705///skeletal system morphogenesis+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0060023///soft palate development 12816 12816 'Col12a1' mRNA 127 170 104 0.58 0.77 0.5 2.01 1.42 1.86 0.616666667 1.763333333 511 352 457 133.6666667 440 3.45E-20 1.710951829 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005595///collagen type XII trimer+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0035987///endodermal cell differentiation 12817 12817 'Col13a1' mRNA 107 100 110 1.85 1.75 2.09 1.64 1.64 1.41 1.896666667 1.563333333 110 105 90 105.6666667 101.6666667 0.84526989 -0.070036354 04974///Protein digestion and absorption GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001763///morphogenesis of a branching structure+++GO:0001958///endochondral ossification+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030903///notochord development+++GO:0098609///cell-cell adhesion 12818 12818 'Col14a1' mRNA 631 624 597 5.28 5.14 5.31 7.45 8.26 8.09 5.243333333 7.933333333 1032 1115 1083 617.3333333 1076.666667 1.02E-16 0.791936364 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0003229///ventricular cardiac muscle tissue development+++GO:0007155///cell adhesion+++GO:0030199///collagen fibril organization+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0061050///regulation of cell growth involved in cardiac muscle cell development 12819 12819 'Col15a1' mRNA 251 239 196 2.51 2.35 2.08 7.56 6.6 7.09 2.313333333 7.083333333 869 741 789 228.6666667 799.6666667 7.21E-49 1.796386909 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization 12821 12821 'Col17a1' mRNA 2 5 2 0.02 0.05 0.02 0.05 0.03 0.03 0.03 0.036666667 6 4 3 3 4.333333333 0.754509107 0.525806258 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding GO:0030198///extracellular matrix organization+++GO:0031581///hemidesmosome assembly 12822 12822 'Col18a1' mRNA 2465 2459 2526 25.88 25.27 28.04 25.32 26.07 23.84 26.39666667 25.07666667 2812 2800 2569 2483.333333 2727 0.138788169 0.12169233 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0007155///cell adhesion+++GO:0008284///positive regulation of cell proliferation+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:2000353///positive regulation of endothelial cell apoptotic process 12823 12823 'Col19a1' mRNA 11 15 10 0.05 0.07 0.05 0.02 0.03 0.04 0.056666667 0.03 5 7 8 12 6.666666667 0.358259765 -0.851560199 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization 12824 12824 'Col2a1' mRNA 1176 1181 1129 12.4 12.17 12.6 16.92 16.83 16.83 12.39 16.86 1845 1785 1771 1162 1800.333333 5.52E-17 0.619991125 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005585///collagen type II trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0042289///MHC class II protein binding+++GO:0042802///identical protein binding+++GO:0043394///proteoglycan binding+++GO:0046872///metal ion binding+++GO:0048407///platelet-derived growth factor binding GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0001894///tissue homeostasis+++GO:0001958///endochondral ossification+++GO:0002062///chondrocyte differentiation+++GO:0003007///heart morphogenesis+++GO:0006029///proteoglycan metabolic process+++GO:0007417///central nervous system development+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0010468///regulation of gene expression+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030903///notochord development+++GO:0035108///limb morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048839///inner ear development+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0060174///limb bud formation+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060348///bone development+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0071599///otic vesicle development+++GO:0071773///cellular response to BMP stimulus+++GO:0097065///anterior head development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 12825 12825 'Col3a1' mRNA 1032 1066 1131 9.87 10.02 11.47 45.26 44.88 43.85 10.45333333 44.66333333 5450 5280 5115 1076.333333 5281.666667 5.54E-218 2.280750601 04611///Platelet activation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005586///collagen type III trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048407///platelet-derived growth factor binding GO:0001501///skeletal system development+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001894///tissue homeostasis+++GO:0002062///chondrocyte differentiation+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007507///heart development+++GO:0009314///response to radiation+++GO:0009612///response to mechanical stimulus+++GO:0010467///gene expression+++GO:0018149///peptide cross-linking+++GO:0021987///cerebral cortex development+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030324///lung development+++GO:0032905///transforming growth factor beta1 production+++GO:0034097///response to cytokine+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035264///multicellular organism growth+++GO:0035904///aorta development+++GO:0036022///limb joint morphogenesis+++GO:0042060///wound healing+++GO:0043588///skin development+++GO:0048144///fibroblast proliferation+++GO:0048251///elastic fiber assembly+++GO:0048565///digestive tract development+++GO:0050777///negative regulation of immune response+++GO:0051216///cartilage development+++GO:0060350///endochondral bone morphogenesis+++GO:0060414///aorta smooth muscle tissue morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0097435///supramolecular fiber organization+++GO:1990776///response to angiotensin+++GO:2001223///negative regulation of neuron migration 12826 12826 'Col4a1' mRNA 970 957 948 7.76 7.52 8.04 18.48 16.52 17.22 7.773333333 17.40666667 2661 2324 2402 958.3333333 2462.333333 6.36E-70 1.348212133 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0048407///platelet-derived growth factor binding GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0007420///brain development+++GO:0007528///neuromuscular junction development+++GO:0030198///extracellular matrix organization+++GO:0030855///epithelial cell differentiation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0061304///retinal blood vessel morphogenesis+++GO:0061333///renal tubule morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071711///basement membrane organization 12827 12827 'Col4a2' mRNA 637 665 631 5.23 5.37 5.49 10.71 9.6 10.4 5.363333333 10.23666667 1503 1316 1414 644.3333333 1411 3.30E-37 1.118294844 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength "GO:0001525///angiogenesis+++GO:0006351///transcription, DNA-templated+++GO:0007568///aging+++GO:0014823///response to activity+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0035987///endodermal cell differentiation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0071560///cellular response to transforming growth factor beta stimulus" 12828 12828 'Col4a3' mRNA 250 251 258 1.53 1.5 1.68 0.73 0.86 0.62 1.57 0.736666667 137 158 113 253 136 2.64E-06 -0.907918921 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0009749///response to glucose+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0032836///glomerular basement membrane development+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0072577///endothelial cell apoptotic process+++GO:1905563///negative regulation of vascular endothelial cell proliferation 12829 12829 'Col4a4' mRNA 535 502 481 3.25 2.96 3.04 1.83 1.38 1.28 3.083333333 1.496666667 346 261 239 506 282 7.12E-09 -0.857190435 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0030198///extracellular matrix organization+++GO:0032836///glomerular basement membrane development 12830 12830 'Col4a5' mRNA 591 623 490 4.8 4.99 4.22 3.29 3.33 3.15 4.67 3.256666667 464 455 429 568 449.3333333 0.005277353 -0.346034459 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007528///neuromuscular junction development+++GO:0030198///extracellular matrix organization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway 12831 12831 'Col5a1' mRNA 401 447 282 2.51 2.74 1.87 3.82 5.24 4.64 2.373333333 4.566666667 704 943 830 376.6666667 825.6666667 5.30E-14 1.13163378 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005588///collagen type V trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0043394///proteoglycan binding+++GO:0048407///platelet-derived growth factor binding "GO:0001568///blood vessel development+++GO:0003007///heart morphogenesis+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0032964///collagen biosynthetic process+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035989///tendon development+++GO:0043588///skin development+++GO:0045112///integrin biosynthetic process+++GO:0048592///eye morphogenesis+++GO:0051128///regulation of cellular component organization+++GO:0097435///supramolecular fiber organization+++GO:1903225///negative regulation of endodermal cell differentiation" 12832 12832 'Col5a2' mRNA 282 355 318 2.25 2.79 2.7 5.56 5.25 5.22 2.58 5.343333333 800 739 728 318.3333333 755.6666667 1.29E-24 1.234932481 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005588///collagen type V trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0043588///skin development+++GO:0048592///eye morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:1903225///negative regulation of endodermal cell differentiation 12833 12833 'Col6a1' mRNA 154 170 138 2.09 2.27 1.99 6.65 7.08 6.64 2.116666667 6.79 564 586 545 154 565 5.10E-41 1.866469553 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0048407///platelet-derived growth factor binding GO:0007155///cell adhesion+++GO:0035987///endodermal cell differentiation+++GO:0071230///cellular response to amino acid stimulus 12834 12834 'Col6a2' mRNA 139 144 119 1.89 1.91 1.74 7.75 7.89 7.5 1.846666667 7.713333333 626 620 591 134 612.3333333 3.49E-56 2.182748447 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0009749///response to glucose 12835 12835 'Col6a3' mRNA 83 97 62 0.5 0.54 0.37 0.36 0.45 0.36 0.47 0.39 71 85 69 80.66666667 75 0.786039899 -0.108363596 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0042383///sarcolemma+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0010951///negative regulation of endopeptidase activity 12836 12836 'Col7a1' mRNA 201 172 172 1.14 0.96 1.03 1.04 0.9 1.16 1.043333333 1.033333333 211 179 229 181.6666667 206.3333333 0.445809804 0.171756364 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 12837 12837 'Col8a1' mRNA 1133 1150 1082 11.84 11.81 11.99 29.28 28.35 27.74 11.88 28.45666667 3227 3053 2962 1121.666667 3080.666667 3.77E-101 1.445931794 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0035987///endodermal cell differentiation+++GO:0048593///camera-type eye morphogenesis+++GO:0050673///epithelial cell proliferation 12839 12839 'Col9a1' mRNA 4491 4613 4439 79.32 80.21 83.24 55.7 54.22 55.08 80.92333333 55 3617 3433 3471 4514.333333 3507 1.05E-10 -0.376589703 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005594///collagen type IX trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001894///tissue homeostasis+++GO:0003417///growth plate cartilage development+++GO:0030198///extracellular matrix organization+++GO:0035988///chondrocyte proliferation+++GO:0051216///cartilage development+++GO:0060349///bone morphogenesis 12840 12840 'Col9a2' mRNA 5621 5305 4031 113.18 105.14 86.1 64.22 61.94 67.44 101.4733333 64.53333333 3669 3456 3731 4985.666667 3618.666667 2.82E-08 -0.46808657 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005594///collagen type IX trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0030198///extracellular matrix organization 12841 12841 'Col9a3' mRNA 4830.86 4954.99 4807 93.75 94.77 98.8 157.83 154.03 153.37 95.77333333 155.0766667 9372.97 8921.84 8802.87 4864.283333 9032.56 1.11E-60 0.880407644 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005581///collagen trimer+++GO:0005594///collagen type IX trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0030198///extracellular matrix organization 12842 12842 'Col1a1' mRNA 186 165 156 1.66 1.45 1.48 11.22 11.59 11.07 1.53 11.29333333 1443 1456 1379 169 1426 5.09E-172 3.066605003 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04611///Platelet activation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005584///collagen type I trimer+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048407///platelet-derived growth factor binding "GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001568///blood vessel development+++GO:0001649///osteoblast differentiation+++GO:0001957///intramembranous ossification+++GO:0001958///endochondral ossification+++GO:0007584///response to nutrient+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0009612///response to mechanical stimulus+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0015031///protein transport+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030335///positive regulation of cell migration+++GO:0031667///response to nutrient levels+++GO:0031960///response to corticosteroid+++GO:0032355///response to estradiol+++GO:0032964///collagen biosynthetic process+++GO:0034504///protein localization to nucleus+++GO:0034505///tooth mineralization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043434///response to peptide hormone+++GO:0043588///skin development+++GO:0043589///skin morphogenesis+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0044691///tooth eruption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048545///response to steroid hormone+++GO:0048705///skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0051591///response to cAMP+++GO:0055093///response to hyperoxia+++GO:0060325///face morphogenesis+++GO:0060346///bone trabecula formation+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0071300///cellular response to retinoic acid+++GO:0071306///cellular response to vitamin E+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902617///response to fluoride+++GO:1902618///cellular response to fluoride" 12843 12843 'Col1a2' mRNA 5888 6216 5934 60.13 62.42 64.28 162.15 150.95 155.1 62.27666667 156.0666667 18279 16626 16936 6012.666667 17280.33333 1.81E-180 1.510194687 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04611///Platelet activation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005584///collagen type I trimer+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix "GO:0002020///protease binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048407///platelet-derived growth factor binding" GO:0001501///skeletal system development+++GO:0001568///blood vessel development+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0008217///regulation of blood pressure+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030282///bone mineralization+++GO:0032963///collagen metabolic process+++GO:0043589///skin morphogenesis+++GO:0070208///protein heterotrimerization+++GO:0071230///cellular response to amino acid stimulus+++GO:0085029///extracellular matrix assembly 12845 12845 'Comp' mRNA 3 8 4 0.07 0.18 0.1 0.54 0.31 0.39 0.116666667 0.413333333 27 15 19 5 20.33333333 0.010024368 2.013373922 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05144///Malaria+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0002020///protease binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005499///vitamin D binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0036122///BMP binding+++GO:0043394///proteoglycan binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0002063///chondrocyte development+++GO:0003416///endochondral bone growth+++GO:0003417///growth plate cartilage development+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0007155///cell adhesion+++GO:0007596///blood coagulation+++GO:0009306///protein secretion+++GO:0010259///multicellular organism aging+++GO:0010260///animal organ senescence+++GO:0010468///regulation of gene expression+++GO:0014829///vascular smooth muscle contraction+++GO:0016485///protein processing+++GO:0030199///collagen fibril organization+++GO:0030282///bone mineralization+++GO:0030500///regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0035264///multicellular organism growth+++GO:0035988///chondrocyte proliferation+++GO:0035989///tendon development+++GO:0043066///negative regulation of apoptotic process+++GO:0043588///skin development+++GO:0048747///muscle fiber development+++GO:0048844///artery morphogenesis+++GO:0050881///musculoskeletal movement+++GO:0050905///neuromuscular process+++GO:0051216///cartilage development+++GO:0055001///muscle cell development+++GO:0060173///limb development+++GO:0060349///bone morphogenesis+++GO:0070527///platelet aggregation+++GO:0097084///vascular smooth muscle cell development+++GO:0098868///bone growth+++GO:1900047///negative regulation of hemostasis+++GO:1902732///positive regulation of chondrocyte proliferation 12846 12846 'Comt' mRNA 3040.58 3195.18 3029.73 79.79 82.16 84.43 104.51 105.56 107.79 82.12666667 105.9533333 4555.08 4511.33 4535.8 3088.496667 4534.07 3.73E-20 0.542332545 00140///Steroid hormone biosynthesis+++00350///Tyrosine metabolism+++04728///Dopaminergic synapse GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0045211///postsynaptic membrane GO:0000287///magnesium ion binding+++GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0016206///catechol O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0102084///L-dopa O-methyltransferase activity+++GO:0102938///orcinol O-methyltransferase activity GO:0006584///catecholamine metabolic process+++GO:0007565///female pregnancy+++GO:0007612///learning+++GO:0007614///short-term memory+++GO:0008210///estrogen metabolic process+++GO:0009712///catechol-containing compound metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0016036///cellular response to phosphate starvation+++GO:0032259///methylation+++GO:0032496///response to lipopolysaccharide+++GO:0032502///developmental process+++GO:0035814///negative regulation of renal sodium excretion+++GO:0042135///neurotransmitter catabolic process+++GO:0042417///dopamine metabolic process+++GO:0042420///dopamine catabolic process+++GO:0042424///catecholamine catabolic process+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0045963///negative regulation of dopamine metabolic process+++GO:0048265///response to pain+++GO:0048609///multicellular organismal reproductive process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050668///positive regulation of homocysteine metabolic process+++GO:0051930///regulation of sensory perception of pain 12847 12847 'Copa' mRNA 4489.29 4913.33 4924.94 52.02 55.97 60.48 62.95 64.79 62.65 56.15666667 63.46333333 6255.74 6284.45 6031.96 4775.853333 6190.716667 1.74E-07 0.360840272 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044297///cell body GO:0003729///mRNA binding+++GO:0005179///hormone activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding "GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030157///pancreatic juice secretion+++GO:0099612///protein localization to axon+++GO:1902463///protein localization to cell leading edge" 12848 12848 'Cops2' mRNA 1514 1485 1470 24.83 23.98 25.58 22.41 21.77 22.33 24.79666667 22.17 1570 1490 1516 1489.666667 1525.333333 0.849001611 0.021704476 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome GO:0003714///transcription corepressor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000338///protein deneddylation+++GO:0001833///inner cell mass cell proliferation+++GO:0006468///protein phosphorylation+++GO:0007595///lactation+++GO:0008283///cell proliferation+++GO:0030182///neuron differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:2000117///negative regulation of cysteine-type endopeptidase activity" 12850 12850 'Coq7' mRNA 1048 1035 906 75.09 73.39 68.84 67.14 74.87 68.94 72.44 70.31666667 1074 1167 1066 996.3333333 1102.333333 0.181397693 0.137137044 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane "GO:0003682///chromatin binding+++GO:0004497///monooxygenase activity+++GO:0008682///2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001306///age-dependent response to oxidative stress+++GO:0001701///in utero embryonic development+++GO:0001841///neural tube formation+++GO:0006744///ubiquinone biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0008340///determination of adult lifespan+++GO:0010468///regulation of gene expression+++GO:0022008///neurogenesis+++GO:0022904///respiratory electron transport chain+++GO:0034599///cellular response to oxidative stress+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070584///mitochondrion morphogenesis+++GO:2000377///regulation of reactive oxygen species metabolic process 12854 12854 'Cort' mRNA 1 1 2 0.11 0.11 0.23 0 0 0.1 0.15 0.033333333 0 0 1 1.333333333 0.333333333 0.568136797 -1.924961872 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0043240///Fanconi anaemia nuclear complex GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity "GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0045187///regulation of circadian sleep/wake cycle, sleep" 12856 12856 'Cox17' mRNA 723 755 941 152.1 159.18 211.89 141.8 155.65 158.53 174.39 151.9933333 758 810 813 806.3333333 793.6666667 0.82925362 -0.040581982 00190///Oxidative phosphorylation+++04714///Thermogenesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0005507///copper ion binding+++GO:0008047///enzyme activator activity+++GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding+++GO:1903136///cuprous ion binding GO:0008284///positive regulation of cell proliferation+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:1904960///positive regulation of cytochrome-c oxidase activity 12857 12857 'Cox4i1' mRNA 10598 10828 10303 998.21 1012.9 1031.22 1059.88 1175.11 1070.17 1014.11 1101.72 12819 13822 12527 10576.33333 13056 1.28E-06 0.292967149 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004129///cytochrome-c oxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0007584///response to nutrient+++GO:1902600///proton transmembrane transport" 12858 12858 'Cox5a' mRNA 3150.02 2868.3 3025.45 324.98 293.77 331.07 457.71 473.33 468.73 316.6066667 466.59 5065.92 5087.07 5002.53 3014.59 5051.84 4.32E-28 0.731932197 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0043209///myelin sheath GO:0004129///cytochrome-c oxidase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:1902600///proton transmembrane transport" 12859 12859 'Cox5b' mRNA 2807.77 2583.77 2842.77 387.64 355.62 416.64 371.48 462.19 425.74 386.6333333 419.8033333 3066.97 3706.87 3385.62 2744.77 3386.486667 0.002124151 0.290786593 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0043209///myelin sheath GO:0004129///cytochrome-c oxidase activity+++GO:0046872///metal ion binding "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0043434///response to peptide hormone" 12861 12861 'Cox6a1' mRNA 7837 7253 7747 1180.37 1090.53 1238.75 1108.56 1308.68 1152.06 1169.883333 1189.766667 8381 9606 8385 7612.333333 8790.666667 0.017282904 0.195256477 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath GO:0004129///cytochrome-c oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0030234///enzyme regulator activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0022900///electron transport chain+++GO:0050790///regulation of catalytic activity+++GO:1902600///proton transmembrane transport" 12862 12862 'Cox6a2' mRNA 0 3 0 0 0.33 0 0.88 1.3 0.91 0.11 1.03 9 13 9 1 10.33333333 0.015332213 3.380286151 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004129///cytochrome-c oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0030234///enzyme regulator activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0022900///electron transport chain+++GO:0050790///regulation of catalytic activity+++GO:1902600///proton transmembrane transport" 12864 12864 'Cox6c' mRNA 3023 2808 3384 507.38 471.36 603.06 605.75 691.78 694.43 527.2666667 663.9866667 4104 4547 4526 3071.666667 4392.333333 9.74E-08 0.500320936 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004129///cytochrome-c oxidase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0008150///biological_process" 12865 12865 'Cox7a1' mRNA 278 248 387 81.18 74.39 121.75 49.74 51.33 63.14 92.44 54.73666667 190 188 230 304.3333333 202.6666667 0.004645092 -0.608757606 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004129///cytochrome-c oxidase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity "GO:0002082///regulation of oxidative phosphorylation+++GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0097250///mitochondrial respiratory chain supercomplex assembly+++GO:1902600///proton transmembrane transport" 12866 12866 'Cox7a2' mRNA 4335 4034 4572 399.63 368.9 447.3 348.62 409.53 390.08 405.2766667 382.7433333 4326 4947 4672 4313.666667 4648.333333 0.354668686 0.093949926 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004129///cytochrome-c oxidase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity "GO:0002082///regulation of oxidative phosphorylation+++GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0097250///mitochondrial respiratory chain supercomplex assembly" 12867 12867 'Cox7c' mRNA 1989 1990 2461 405.2 406.97 532.51 413.95 515.56 463.44 448.2266667 464.3166667 2304 2780 2478 2146.666667 2520.666667 0.07871116 0.215246266 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004129///cytochrome-c oxidase activity+++GO:0005515///protein binding "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen" 12868 12868 'Cox8a' mRNA 9942 9500 10144 1467.29 1399.18 1589.37 1182.01 1393.97 1299.92 1485.28 1291.966667 9122 10446 9659 9862 9742.333333 0.770892676 -0.030228728 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045277///respiratory chain complex IV GO:0004129///cytochrome-c oxidase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen" 12869 12869 'Cox8b' mRNA 74 91 108 22.69 28.28 35.25 14.18 15.24 20.2 28.74 16.54 52 54 71 91 59 0.049460707 -0.642327921 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045277///respiratory chain complex IV GO:0004129///cytochrome-c oxidase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen" 12870 12870 'Cp' mRNA 6346 6306 6071 76.82 75.66 78.7 208.84 199.5 200.94 77.06 203.0933333 18257 17073 17091 6241 17473.66667 4.76E-201 1.473089536 00860///Porphyrin metabolism+++04216///Ferroptosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0046658///anchored component of plasma membrane GO:0004322///ferroxidase activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006826///iron ion transport+++GO:0046688///response to copper ion+++GO:0055072///iron ion homeostasis 12873 12873 'Cpa3' mRNA 7 7 3 0.29 0.28 0.13 0.11 0.05 0.07 0.233333333 0.076666667 3 1 2 5.666666667 2 0.306262685 -1.505474064 04614///Renin-angiotensin system+++04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005615///extracellular space+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002002///regulation of angiotensin levels in blood+++GO:0006508///proteolysis 12874 12874 'Cpd' mRNA 3146 3275 2996 18.03 18.44 18.21 18.36 15.89 17.4 18.22666667 17.21666667 3690 3120 3388 3139 3399.333333 0.172729359 0.102706328 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051721///protein phosphatase 2A binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016485///protein processing 12876 12876 'Cpe' mRNA 8568 9061 2840 222.66 231.92 78.29 33.58 60.42 54.28 177.6233333 49.42666667 1486 2610 2325 6823 2140.333333 0.003422079 -1.655194189 04940///Type I diabetes mellitus GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0097060///synaptic membrane GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0042043///neurexin family protein binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0050897///cobalt ion binding GO:0003214///cardiac left ventricle morphogenesis+++GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016485///protein processing+++GO:0030070///insulin processing+++GO:0030072///peptide hormone secretion+++GO:0033366///protein localization to secretory granule+++GO:0034230///enkephalin processing+++GO:0043171///peptide catabolic process+++GO:0072657///protein localization to membrane+++GO:2000173///negative regulation of branching morphogenesis of a nerve 12877 12877 'Cpeb1' mRNA 481 512 489 7.33 7.56 7.48 5.91 5.34 5.89 7.456666667 5.713333333 438 380 407 494 408.3333333 0.026802124 -0.287673138 04114///Oocyte meiosis+++04320///Dorso-ventral axis formation+++04914///Progesterone-mediated oocyte maturation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0072687///meiotic spindle+++GO:1990124///messenger ribonucleoprotein complex "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0043022///ribosome binding+++GO:0045182///translation regulator activity+++GO:0046872///metal ion binding" GO:0006397///mRNA processing+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0007130///synaptonemal complex assembly+++GO:0008285///negative regulation of cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0017148///negative regulation of translation+++GO:0030335///positive regulation of cell migration+++GO:0032869///cellular response to insulin stimulus+++GO:0045727///positive regulation of translation+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0051028///mRNA transport+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071456///cellular response to hypoxia+++GO:1900365///positive regulation of mRNA polyadenylation+++GO:2000766///negative regulation of cytoplasmic translation 12879 12879 'Cys1' mRNA 288 284 148 7.87 7.52 3.9 3.16 3.57 3.65 6.43 3.46 141 154 150 240 148.3333333 0.003389881 -0.692206645 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0060170///ciliary membrane GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding "GO:0001822///kidney development+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development" 12889 12889 'Cplx1' mRNA 33 22 19 0.85 0.56 0.52 0.25 0.18 0.14 0.643333333 0.19 11 8 6 24.66666667 8.333333333 0.017428764 -1.574534752 04721///Synaptic vesicle cycle GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031201///SNARE complex+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0070032///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005326///neurotransmitter transporter activity+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding GO:0006836///neurotransmitter transport+++GO:0006887///exocytosis+++GO:0016079///synaptic vesicle exocytosis+++GO:0030073///insulin secretion+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0046928///regulation of neurotransmitter secretion+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse 12890 12890 'Cplx2' mRNA 763.61 765.38 473.71 8 7.89 5.21 1.9 1.52 2.12 7.033333333 1.846666667 211.11 168.23 229.52 667.5666667 202.9533333 1.93E-24 -1.721502574 04721///Synaptic vesicle cycle GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031201///SNARE complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0070033///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0048306///calcium-dependent protein binding GO:0006836///neurotransmitter transport+++GO:0006887///exocytosis+++GO:0007399///nervous system development+++GO:0016079///synaptic vesicle exocytosis+++GO:0030154///cell differentiation+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0031915///positive regulation of synaptic plasticity+++GO:0043303///mast cell degranulation+++GO:0046928///regulation of neurotransmitter secretion 12891 12891 'Cpne6' mRNA 0 1 5 0 0.03 0.15 0.12 0.18 0.08 0.06 0.126666667 5 7 3 2 5 0.458619251 1.27322197 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045334///clathrin-coated endocytic vesicle GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0030154///cell differentiation+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 12892 12892 'Cpox' mRNA 199.78 213.08 140.8 3.43 3.6 2.56 2.12 2.07 2.12 3.196666667 2.103333333 142.13 135.25 137.29 184.5533333 138.2233333 0.058891557 -0.41973449 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0016020///membrane GO:0004109///coproporphyrinogen oxidase activity+++GO:0005212///structural constituent of eye lens+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0010035///response to inorganic substance+++GO:0010039///response to iron ion+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010288///response to lead ion+++GO:0017085///response to insecticide+++GO:0046685///response to arsenic-containing substance+++GO:0051597///response to methylmercury 12894 12894 'Cpt1a' mRNA 1060 1012 1003 13.25 12.48 13.4 18.17 16.64 16.3 13.04333333 17.03666667 1659 1486 1437 1025 1527.333333 3.23E-11 0.562479062 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04936///Alcoholic liver disease GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004095///carnitine O-palmitoyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042802///identical protein binding+++GO:1990698///palmitoleoyltransferase activity" GO:0001676///long-chain fatty acid metabolic process+++GO:0006006///glucose metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006641///triglyceride metabolic process+++GO:0009437///carnitine metabolic process+++GO:0010876///lipid localization+++GO:0010883///regulation of lipid storage+++GO:0014070///response to organic cyclic compound+++GO:0030855///epithelial cell differentiation+++GO:0031667///response to nutrient levels+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0042493///response to drug+++GO:0042755///eating behavior+++GO:0043279///response to alkaloid+++GO:0045471///response to ethanol+++GO:0046320///regulation of fatty acid oxidation+++GO:0046677///response to antibiotic+++GO:0050796///regulation of insulin secretion+++GO:0071398///cellular response to fatty acid+++GO:0097421///liver regeneration+++GO:1904772///response to tetrachloromethane 12895 12895 'Cpt1b' mRNA 186 225 153 3.54 4.21 3.09 2.41 1.96 2.19 3.613333333 2.186666667 146 116 128 188 130 0.013493405 -0.539625246 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04936///Alcoholic liver disease+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004095///carnitine O-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009437///carnitine metabolic process+++GO:0009637///response to blue light+++GO:0015909///long-chain fatty acid transport 12896 12896 'Cpt2' mRNA 827 832 839 19.71 19.53 21.22 20.04 22.46 23.49 20.15333333 21.99666667 967 1058 1097 832.6666667 1040.666667 0.002590503 0.310063901 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04714///Thermogenesis+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane "GO:0004095///carnitine O-palmitoyltransferase activity+++GO:0008458///carnitine O-octanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0001676///long-chain fatty acid metabolic process+++GO:0001701///in utero embryonic development+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009437///carnitine metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis 12902 12902 'Cr2' mRNA 19 11 19 0.15 0.09 0.15 0.07 0.08 0.07 0.13 0.073333333 10 11 9 16.33333333 10 0.357643915 -0.726240088 04610///Complement and coagulation cascades+++04640///Hematopoietic cell lineage+++04662///B cell receptor signaling pathway+++05169///Epstein-Barr virus infection GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0001848///complement binding+++GO:0003677///DNA binding+++GO:0004875///complement receptor activity+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042803///protein homodimerization activity "GO:0002376///immune system process+++GO:0002430///complement receptor mediated signaling pathway+++GO:0006954///inflammatory response+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0016064///immunoglobulin mediated immune response+++GO:0030183///B cell differentiation+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation+++GO:0045087///innate immune response+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0051216///cartilage development+++GO:0060348///bone development+++GO:0071222///cellular response to lipopolysaccharide" 12904 12904 'Crabp2' mRNA 295 328 293 21.54 23.71 22.71 47.56 49.14 40.78 22.65333333 45.82666667 746 751 618 305.3333333 705 1.46E-21 1.196275434 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0001972///retinoic acid binding+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:0030332///cyclin binding GO:0002138///retinoic acid biosynthetic process+++GO:0015908///fatty acid transport+++GO:0035115///embryonic forelimb morphogenesis+++GO:0042573///retinoic acid metabolic process+++GO:0048672///positive regulation of collateral sprouting 12905 12905 'Cradd' mRNA 795.26 879.7 837.85 23.41 25.56 25.85 18.22 19.19 19.18 24.94 18.86333333 748.69 758.52 754.9 837.6033333 754.0366667 0.135311386 -0.163874248 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0002020///protease binding+++GO:0030674///protein binding, bridging+++GO:0070513///death domain binding" "GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007165///signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0097190///apoptotic signaling pathway+++GO:2001235///positive regulation of apoptotic signaling pathway" 12908 12908 'Crat' mRNA 1472 1418 1549 27.64 26.07 31.24 41.64 35.68 39.7 28.31666667 39.00666667 2544 2143 2337 1479.666667 2341.333333 4.45E-14 0.646259303 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane "GO:0003997///acyl-CoA oxidase activity+++GO:0004092///carnitine O-acetyltransferase activity+++GO:0008458///carnitine O-octanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0019254///carnitine metabolic process, CoA-linked+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0046459///short-chain fatty acid metabolic process+++GO:0051791///medium-chain fatty acid metabolic process" 12909 12909 'Crcp' mRNA 673 699 678 27.05 27.72 28.91 27.75 26.4 26.73 27.89333333 26.96 793 736 739 683.3333333 756 0.242672069 0.133210284 03020///RNA polymerase GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009360///DNA polymerase III complex+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030880///RNA polymerase complex+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0002376///immune system process+++GO:0006352///DNA-templated transcription, initiation+++GO:0006383///transcription by RNA polymerase III+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0007218///neuropeptide signaling pathway+++GO:0044237///cellular metabolic process+++GO:0045087///innate immune response+++GO:0051607///defense response to virus" 12912 12912 'Creb1' mRNA 1027 1112 1066 7.93 8.41 8.57 7.54 6.87 6.87 8.303333333 7.093333333 1115 991 993 1068.333333 1033 0.597214093 -0.061703948 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04380///Osteoclast differentiation+++04612///Antigen processing and presentation+++04668///TNF signaling pathway+++04710///Circadian rhythm+++04713///Circadian entrainment+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:1990589///ATF4-CREB1 transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0001225///RNA polymerase II transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030544///Hsp70 protein binding+++GO:0035035///histone acetyltransferase binding+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990763///arrestin family protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007409///axonogenesis+++GO:0007568///aging+++GO:0007595///lactation+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0008361///regulation of cell size+++GO:0008542///visual learning+++GO:0009410///response to xenobiotic stimulus+++GO:0010033///response to organic substance+++GO:0010629///negative regulation of gene expression+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0014823///response to activity+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030879///mammary gland development+++GO:0032916///positive regulation of transforming growth factor beta3 production+++GO:0033363///secretory granule organization+++GO:0033762///response to glucagon+++GO:0034670///chemotaxis to arachidonic acid+++GO:0035094///response to nicotine+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042493///response to drug+++GO:0042752///regulation of circadian rhythm+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046887///positive regulation of hormone secretion+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048145///regulation of fibroblast proliferation+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0055025///positive regulation of cardiac muscle tissue development+++GO:0060251///regulation of glial cell proliferation+++GO:0060428///lung epithelium development+++GO:0060430///lung saccule development+++GO:0060509///type I pneumocyte differentiation+++GO:0071294///cellular response to zinc ion+++GO:0071300///cellular response to retinoic acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901215///negative regulation of neuron death+++GO:1902065///response to L-glutamate+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:1990830///cellular response to leukemia inhibitory factor" 12913 12913 'Creb3' mRNA 1480.84 1489 1524 55.81 55.34 60.93 79.32 79.54 74.56 57.36 77.80666667 2417.86 2366 2199 1497.946667 2327.62 5.28E-16 0.622632042 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043025///neuronal cell body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008140///cAMP response element binding protein binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001558///regulation of cell growth+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006935///chemotaxis+++GO:0006986///response to unfolded protein+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0019043///establishment of viral latency+++GO:0019046///release from viral latency+++GO:0030335///positive regulation of cell migration+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042127///regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050930///induction of positive chemotaxis+++GO:0051928///positive regulation of calcium ion transport+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090045///positive regulation of deacetylase activity+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway" 12914 12914 'Crebbp' mRNA 3034 3034 3028 14.73 14.52 15.6 13.83 11.05 12.88 14.95 12.58666667 3273 2554 2955 3032 2927.333333 0.519069321 -0.065464388 "04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04350///TGF-beta signaling pathway+++04520///Adherens junction+++04630///JAK-STAT signaling pathway+++04720///Long-term potentiation+++04916///Melanogenesis+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05016///Huntington disease+++05152///Tuberculosis+++05161///Hepatitis B+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma+++05215///Prostate cancer" GO:0000123///histone acetyltransferase complex+++GO:0000785///chromatin+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001093///TFIIB-class transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008140///cAMP response element binding protein binding+++GO:0008270///zinc ion binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0033613///activating transcription factor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0043426///MRF binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0097718///disordered domain specific binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006473///protein acetylation+++GO:0007616///long-term memory+++GO:0008283///cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016573///histone acetylation+++GO:0018076///N-terminal peptidyl-lysine acetylation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030718///germ-line stem cell population maintenance+++GO:0031648///protein destabilization+++GO:0032688///negative regulation of interferon-beta production+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0034644///cellular response to UV+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048148///behavioral response to cocaine+++GO:0048511///rhythmic process+++GO:0048525///negative regulation of viral process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060325///face morphogenesis+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0060999///positive regulation of dendritic spine development+++GO:0098586///cellular response to virus+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1990258///histone glutamine methylation" 12915 12915 'Atf6b' mRNA 1700 1683 1555 36.83 35.9 35.74 38.95 38.19 35.31 36.15666667 37.48333333 2068 1980 1815 1646 1954.333333 0.002405856 0.236577344 "04022///cGMP-PKG signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation" GO:0000794///condensed nuclear chromosome+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005815///microtubule organizing center+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0035497///cAMP response element binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0007076///mitotic chromosome condensation+++GO:0016458///gene silencing+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903892///negative regulation of ATF6-mediated unfolded protein response+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 12916 12916 'Crem' mRNA 284.37 305.5 315.6 5.82 6.1 7.5 12.99 12.8 11.72 6.473333333 12.50333333 658.2 663.66 602.45 301.8233333 641.4366667 6.60E-18 1.07561585 04261///Adrenergic signaling in cardiomyocytes GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:1990589///ATF4-CREB1 transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006006///glucose metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006631///fatty acid metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0007283///spermatogenesis+++GO:0007623///circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0051591///response to cAMP" 12918 12918 'Crh' mRNA 41 51 44 1.87 2.3 2.13 0.08 0.12 0.08 2.1 0.093333333 2 3 2 45.33333333 2.333333333 3.01E-09 -4.29022609 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04730///Long-term depression+++04934///Cushing syndrome+++05034///Alcoholism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043196///varicosity+++GO:0043204///perikaryon+++GO:0045202///synapse GO:0005179///hormone activity+++GO:0017045///corticotropin-releasing hormone activity+++GO:0051430///corticotropin-releasing hormone receptor 1 binding+++GO:0051431///corticotropin-releasing hormone receptor 2 binding "GO:0001934///positive regulation of protein phosphorylation+++GO:0001963///synaptic transmission, dopaminergic+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006704///glucocorticoid biosynthetic process+++GO:0006954///inflammatory response+++GO:0007565///female pregnancy+++GO:0007611///learning or memory+++GO:0008202///steroid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008306///associative learning+++GO:0008628///hormone-mediated apoptotic signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0010942///positive regulation of cell death+++GO:0014062///regulation of serotonin secretion+++GO:0016101///diterpenoid metabolic process+++GO:0021854///hypothalamus development+++GO:0030324///lung development+++GO:0030325///adrenal gland development+++GO:0032811///negative regulation of epinephrine secretion+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0035641///locomotory exploration behavior+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0035902///response to immobilization stress+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045471///response to ethanol+++GO:0045472///response to ether+++GO:0048265///response to pain+++GO:0050801///ion homeostasis+++GO:0051412///response to corticosterone+++GO:0051461///positive regulation of corticotropin secretion+++GO:0051464///positive regulation of cortisol secretion+++GO:0060291///long-term synaptic potentiation+++GO:0060456///positive regulation of digestive system process+++GO:0060548///negative regulation of cell death+++GO:0070093///negative regulation of glucagon secretion+++GO:0071314///cellular response to cocaine+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090280///positive regulation of calcium ion import+++GO:2000310///regulation of NMDA receptor activity+++GO:2000854///positive regulation of corticosterone secretion+++GO:2000987///positive regulation of behavioral fear response" 12919 12919 'Crhbp' mRNA 2175 2202 2134 75.23 75.08 78.3 3.76 4.19 4.32 76.20333333 4.09 125 136 139 2170.333333 133.3333333 0 -4.036534527 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005767///secondary lysosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0031045///dense core granule+++GO:0043196///varicosity+++GO:0043204///perikaryon+++GO:0043679///axon terminus GO:0042277///peptide binding+++GO:0051424///corticotropin-releasing hormone binding "GO:0001963///synaptic transmission, dopaminergic+++GO:0002125///maternal aggressive behavior+++GO:0006954///inflammatory response+++GO:0007565///female pregnancy+++GO:0009755///hormone-mediated signaling pathway+++GO:0035690///cellular response to drug+++GO:0035865///cellular response to potassium ion+++GO:0035903///cellular response to immobilization stress+++GO:0042445///hormone metabolic process+++GO:0045055///regulated exocytosis+++GO:0048149///behavioral response to ethanol+++GO:0051459///regulation of corticotropin secretion+++GO:0051460///negative regulation of corticotropin secretion+++GO:0071277///cellular response to calcium ion+++GO:0071314///cellular response to cocaine+++GO:0071320///cellular response to cAMP+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071391///cellular response to estrogen stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0080135///regulation of cellular response to stress+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:1900011///negative regulation of corticotropin-releasing hormone receptor activity+++GO:2000310///regulation of NMDA receptor activity" 12921 12921 'Crhr1' mRNA 3 1 2 0.07 0.01 0.05 0.02 0 0 0.043333333 0.006666667 1 0 0 2 0.333333333 0.375343153 -2.496394607 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04730///Long-term depression+++04934///Cushing syndrome GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0031982///vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell GO:0001965///G-protein alpha-subunit binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0015056///corticotrophin-releasing factor receptor activity+++GO:0017046///peptide hormone binding+++GO:0042277///peptide binding+++GO:0043404///corticotropin-releasing hormone receptor activity+++GO:0044877///protein-containing complex binding+++GO:0051424///corticotropin-releasing hormone binding "GO:0001666///response to hypoxia+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0007613///memory+++GO:0007631///feeding behavior+++GO:0008542///visual learning+++GO:0009755///hormone-mediated signaling pathway+++GO:0010578///regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway+++GO:0021854///hypothalamus development+++GO:0030325///adrenal gland development+++GO:0030855///epithelial cell differentiation+++GO:0032811///negative regulation of epinephrine secretion+++GO:0035641///locomotory exploration behavior+++GO:0035902///response to immobilization stress+++GO:0042596///fear response+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0048148///behavioral response to cocaine+++GO:0048149///behavioral response to ethanol+++GO:0048167///regulation of synaptic plasticity+++GO:0048266///behavioral response to pain+++GO:0051458///corticotropin secretion+++GO:0051602///response to electrical stimulus+++GO:0051867///general adaptation syndrome, behavioral process+++GO:0060291///long-term synaptic potentiation+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:1901215///negative regulation of neuron death+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:2000252///negative regulation of feeding behavior+++GO:2000852///regulation of corticosterone secretion" 12922 12922 'Crhr2' mRNA 2 2 3 0.04 0.04 0.07 0 0 0 0.05 0 0 0 0 2.333333333 0 0.177825991 -3.687726857 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04934///Cushing syndrome GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043196///varicosity+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0070852///cell body fiber GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0015056///corticotrophin-releasing factor receptor activity+++GO:0017046///peptide hormone binding+++GO:0043404///corticotropin-releasing hormone receptor activity GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0010460///positive regulation of heart rate+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0014064///positive regulation of serotonin secretion+++GO:0016525///negative regulation of angiogenesis+++GO:0019233///sensory perception of pain+++GO:0030855///epithelial cell differentiation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032811///negative regulation of epinephrine secretion+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0035482///gastric motility+++GO:0042423///catecholamine biosynthetic process+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045777///positive regulation of blood pressure+++GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0048630///skeletal muscle tissue growth+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060291///long-term synaptic potentiation+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0090281///negative regulation of calcium ion import+++GO:0106071///positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000252///negative regulation of feeding behavior+++GO:2000293///negative regulation of defecation+++GO:2000573///positive regulation of DNA biosynthetic process 12925 12925 'Crip1' mRNA 1241 1250 1502 254.83 257.71 327.6 517.64 606.52 614.1 280.0466667 579.42 2858 3244 3257 1331 3119.666667 2.58E-32 1.213064353 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010043///response to zinc ion+++GO:0010468///regulation of gene expression+++GO:0071236///cellular response to antibiotic+++GO:0071493///cellular response to UV-B 12927 12927 'Bcar1' mRNA 1364 1505 1004 23.81 25.82 18.65 16.01 17.33 19.08 22.76 17.47333333 1051 1111 1212 1291 1124.666667 0.108855928 -0.202096475 "04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04935///Growth hormone synthesis, secretion and action+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05163///Human cytomegalovirus infection" GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008286///insulin receptor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0060326///cell chemotaxis+++GO:0071732///cellular response to nitric oxide+++GO:0086100///endothelin receptor signaling pathway+++GO:0090527///actin filament reorganization+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1990859///cellular response to endothelin 12928 12928 'Crk' mRNA 1411.15 1440.84 796.83 13.46 13.21 8.36 10.42 9.79 11.91 11.67666667 10.70666667 1224.11 1157.19 1380.05 1216.273333 1253.783333 0.889954736 0.045622085 "04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma+++05220///Chronic myeloid leukemia" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft "GO:0001784///phosphotyrosine residue binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0016301///kinase activity+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030674///protein binding, bridging+++GO:0030971///receptor tyrosine kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035591///signaling adaptor activity+++GO:0042169///SH2 domain binding+++GO:0043621///protein self-association+++GO:0045309///protein phosphorylated amino acid binding+++GO:0046875///ephrin receptor binding+++GO:0097110///scaffold protein binding+++GO:1990782///protein tyrosine kinase binding" GO:0001764///neuron migration+++GO:0001878///response to yeast+++GO:0002685///regulation of leukocyte migration+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0009966///regulation of signal transduction+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030010///establishment of cell polarity+++GO:0030036///actin cytoskeleton organization+++GO:0030307///positive regulation of cell growth+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0035020///regulation of Rac protein signal transduction+++GO:0035685///helper T cell diapedesis+++GO:0035728///response to hepatocyte growth factor+++GO:0038026///reelin-mediated signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0043087///regulation of GTPase activity+++GO:0043393///regulation of protein binding+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0048013///ephrin receptor signaling pathway+++GO:0050773///regulation of dendrite development+++GO:0060326///cell chemotaxis+++GO:0061045///negative regulation of wound healing+++GO:0061847///response to cholecystokinin+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0090630///activation of GTPase activity+++GO:0098749///cerebellar neuron development+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901652///response to peptide+++GO:1902531///regulation of intracellular signal transduction+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:1990859///cellular response to endothelin+++GO:2000146///negative regulation of cell motility+++GO:2000404///regulation of T cell migration 12929 12929 'Crkl' mRNA 1473 1509 1423 15.59 15.7 15.99 15.58 16.27 15.51 15.76 15.78666667 1693 1731 1634 1468.333333 1686 0.018639364 0.188290331 "04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma+++05220///Chronic myeloid leukemia" GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0035591///signaling adaptor activity+++GO:0042802///identical protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000187///activation of MAPK activity+++GO:0001558///regulation of cell growth+++GO:0001568///blood vessel development+++GO:0001655///urogenital system development+++GO:0001764///neuron migration+++GO:0001783///B cell apoptotic process+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002685///regulation of leukocyte migration+++GO:0003151///outflow tract morphogenesis+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007389///pattern specification process+++GO:0007416///synapse assembly+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008584///male gonad development+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030010///establishment of cell polarity+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0035685///helper T cell diapedesis+++GO:0035690///cellular response to drug+++GO:0038026///reelin-mediated signaling pathway+++GO:0043410///positive regulation of MAPK cascade+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048538///thymus development+++GO:0050773///regulation of dendrite development+++GO:0050852///T cell receptor signaling pathway+++GO:0060017///parathyroid gland development+++GO:0060326///cell chemotaxis+++GO:0060465///pharynx development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071774///response to fibroblast growth factor+++GO:0086100///endothelin receptor signaling pathway+++GO:0090630///activation of GTPase activity+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0098749///cerebellar neuron development+++GO:0098761///cellular response to interleukin-7+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1903977///positive regulation of glial cell migration+++GO:1904393///regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:1904888///cranial skeletal system development+++GO:2000404///regulation of T cell migration 12931 12931 'Crlf1' mRNA 57 48 13 2.32 1.91 0.51 3.53 4.82 4.61 1.58 4.32 110 145 142 39.33333333 132.3333333 2.28E-06 1.760709595 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0043235///receptor complex+++GO:0097058///CRLF-CLCF1 complex GO:0004896///cytokine receptor activity+++GO:0005125///cytokine activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0019955///cytokine binding GO:0001657///ureteric bud development+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043524///negative regulation of neuron apoptotic process+++GO:2000672///negative regulation of motor neuron apoptotic process 12933 12933 'Crmp1' mRNA 151 153 155 2.8 2.76 3.05 0.5 0.91 0.38 2.87 0.596666667 31 55 23 153 36.33333333 1.22E-11 -2.083782741 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon "GO:0004157///dihydropyrimidinase activity+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding" GO:0000226///microtubule cytoskeleton organization+++GO:0006208///pyrimidine nucleobase catabolic process+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0010977///negative regulation of neuron projection development+++GO:0048666///neuron development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1904530///negative regulation of actin filament binding 12934 12934 'Dpysl2' mRNA 7836 7385 7423 94.95 88 95.39 71.52 59.19 67.73 92.78 66.14666667 6797 5496 6234 7548 6175.666667 2.20E-05 -0.303686258 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043209///myelin sheath+++GO:0098793///presynapse "GO:0004157///dihydropyrimidinase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding" GO:0001975///response to amphetamine+++GO:0006208///pyrimidine nucleobase catabolic process+++GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0010975///regulation of neuron projection development+++GO:0014049///positive regulation of glutamate secretion+++GO:0021510///spinal cord development+++GO:0021772///olfactory bulb development+++GO:0030154///cell differentiation+++GO:0030516///regulation of axon extension+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0045664///regulation of neuron differentiation+++GO:0048489///synaptic vesicle transport 12937 12937 'Pcdha6' mRNA 6.38 0 8.08 0.05 0 0.07 0 0 0 0.04 0 0 0 0 4.82 0 0.039601263 -4.707950623 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0004930///G protein-coupled receptor activity+++GO:0004949///cannabinoid receptor activity+++GO:0005509///calcium ion binding "GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0019233///sensory perception of pain+++GO:0030595///leukocyte chemotaxis+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032496///response to lipopolysaccharide+++GO:0033004///negative regulation of mast cell activation+++GO:0038171///cannabinoid signaling pathway+++GO:0045759///negative regulation of action potential+++GO:0050728///negative regulation of inflammatory response+++GO:0051001///negative regulation of nitric-oxide synthase activity" 12939 12939 'Pcdha7' mRNA 6.94 11.91 0 0.07 0.12 0 0 0 0 0.063333333 0 0 0 0 6.283333333 0 0.024359564 -4.917421564 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009988///cell-cell recognition 12941 12941 'Pcdha5' mRNA 5.33 8.63 2.1 0.05 0.08 0.02 0 0 0 0.05 0 0 0 0 5.353333333 0 0.020738895 -4.753727784 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 12942 12942 'Pcdha11' mRNA 88.16 89.98 104 0.89 0.9 1.12 0 0.1 0.08 0.97 0.06 0 11.22 8.63 94.04666667 6.616666667 8.87E-05 -3.889103959 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 12943 12943 'Pcdha10' mRNA 3.47 3.52 9 0.04 0.04 0.1 0.04 0 0 0.06 0.013333333 5.03 0 0 5.33 1.676666667 0.372612173 -1.648383231 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 12946 12946 'Cr1l' mRNA 1240 1374 1252 43.27 47.28 46.36 52.22 50.52 50.52 45.63666667 51.08666667 1721 1623 1610 1288.666667 1651.333333 1.27E-05 0.346091 04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage+++05134///Legionellosis+++05140///Leishmaniasis+++05144///Malaria+++05152///Tuberculosis GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043235///receptor complex+++GO:0044853///plasma membrane raft GO:0001851///complement component C3b binding+++GO:0001855///complement component C4b binding+++GO:0001861///complement component C4b receptor activity+++GO:0004877///complement component C3b receptor activity "GO:0001701///in utero embryonic development+++GO:0002376///immune system process+++GO:0002430///complement receptor mediated signaling pathway+++GO:0002456///T cell mediated immunity+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0007275///multicellular organism development+++GO:0007565///female pregnancy+++GO:0030449///regulation of complement activation+++GO:0045087///innate immune response+++GO:0045916///negative regulation of complement activation+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0071456///cellular response to hypoxia+++GO:1903659///regulation of complement-dependent cytotoxicity" 12950 12950 'Hapln1' mRNA 46 44 46 0.49 0.46 0.52 0.38 0.26 0.46 0.49 0.366666667 41 28 49 45.33333333 39.33333333 0.664494493 -0.219472801 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix GO:0005540///hyaluronic acid binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development 12951 12951 'Crx' mRNA 8.3 12.01 10.57 0.16 0.23 0.21 0.01 0.02 0.04 0.2 0.023333333 0.54 1 2.39 10.29333333 1.31 0.01377404 -3.328337502 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0035257///nuclear hormone receptor binding+++GO:0043522///leucine zipper domain binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0007623///circadian rhythm+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046534///positive regulation of photoreceptor cell differentiation+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye" 12952 12952 'Cry1' mRNA 622 596 658 11.27 10.64 12.7 10.11 10.33 9.77 11.53666667 10.07 640 640 599 625.3333333 626.3333333 0.938991394 -0.012018657 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0009881///photoreceptor activity+++GO:0016922///nuclear receptor binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0035257///nuclear hormone receptor binding+++GO:0042826///histone deacetylase binding+++GO:0070888///E-box binding+++GO:0071949///FAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006094///gluconeogenesis+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0014823///response to activity+++GO:0018298///protein-chromophore linkage+++GO:0019915///lipid storage+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0033762///response to glucagon+++GO:0042593///glucose homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0042754///negative regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050896///response to stimulus+++GO:2000001///regulation of DNA damage checkpoint+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway+++GO:2000850///negative regulation of glucocorticoid secretion" 12953 12953 'Cry2' mRNA 2340 2424 2385 31.63 32.22 34.18 18.3 16.24 17.14 32.67666667 17.22666667 1559 1350 1414 2383 1441 1.02E-22 -0.739421591 04710///Circadian rhythm GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0009881///photoreceptor activity+++GO:0016922///nuclear receptor binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0035257///nuclear hormone receptor binding+++GO:0071949///FAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0014823///response to activity+++GO:0018298///protein-chromophore linkage+++GO:0019915///lipid storage+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0042593///glucose homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0042754///negative regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050896///response to stimulus+++GO:2000118///regulation of sodium-dependent phosphate transport+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway+++GO:2000850///negative regulation of glucocorticoid secretion" 12954 12954 'Cryaa' mRNA 15 3 4 0.83 0.16 0.23 0.05 0 0 0.406666667 0.016666667 1 0 0 7.333333333 0.333333333 0.017557566 -4.356850183 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0005198///structural molecule activity+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002088///lens development in camera-type eye+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0007015///actin filament organization+++GO:0007017///microtubule-based process+++GO:0007021///tubulin complex assembly+++GO:0007601///visual perception+++GO:0010259///multicellular organism aging+++GO:0010288///response to lead ion+++GO:0010629///negative regulation of gene expression+++GO:0030307///positive regulation of cell growth+++GO:0032387///negative regulation of intracellular transport+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0050821///protein stabilization+++GO:0051384///response to glucocorticoid+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0070141///response to UV-A+++GO:0070309///lens fiber cell morphogenesis 12955 12955 'Cryab' mRNA 10942.14 10924.35 10585.39 739.85 734.7 761.73 893.92 971.64 891.22 745.4266667 918.9266667 14952.3 15821.51 14368.51 10817.29333 15047.44 1.10E-15 0.464813735 04141///Protein processing in endoplasmic reticulum+++04213///Longevity regulating pathway - multiple species GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0030018///Z disc+++GO:0030424///axon+++GO:0031430///M band+++GO:0031674///I band+++GO:0032432///actin filament bundle+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0043292///contractile fiber+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0097512///cardiac myofibril GO:0001540///amyloid-beta binding+++GO:0005198///structural molecule activity+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008092///cytoskeletal protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding "GO:0001666///response to hypoxia+++GO:0002088///lens development in camera-type eye+++GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007517///muscle organ development+++GO:0007568///aging+++GO:0010259///multicellular organism aging+++GO:0010629///negative regulation of gene expression+++GO:0010941///regulation of cell death+++GO:0030308///negative regulation of cell growth+++GO:0031109///microtubule polymerization or depolymerization+++GO:0031333///negative regulation of protein complex assembly+++GO:0032355///response to estradiol+++GO:0032387///negative regulation of intracellular transport+++GO:0042542///response to hydrogen peroxide+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050821///protein stabilization+++GO:0051403///stress-activated MAPK cascade+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0071480///cellular response to gamma radiation+++GO:1905907///negative regulation of amyloid fibril formation+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 12957 12957 'Cryba1' mRNA 0 0 1 0 0 0.09 0 0 0 0.03 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome GO:0005212///structural constituent of eye lens+++GO:0042802///identical protein binding GO:0001818///negative regulation of cytokine production+++GO:0002088///lens development in camera-type eye+++GO:0006909///phagocytosis+++GO:0007601///visual perception+++GO:0010506///regulation of autophagy+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0032007///negative regulation of TOR signaling+++GO:0043010///camera-type eye development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2000210///positive regulation of anoikis 12959 12959 'Cryba4' mRNA 19 11 8 1.59 0.91 0.78 3.66 2.87 2.51 1.093333333 3.013333333 50 39 35 12.66666667 41.33333333 0.001160956 1.699316633 GO:0005212///structural constituent of eye lens+++GO:0042802///identical protein binding GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0043010///camera-type eye development 12960 12960 'Crybb1' mRNA 29 17 39 2.19 1.27 3.12 1.71 1.35 2.12 2.193333333 1.726666667 26 20 31 28.33333333 25.66666667 0.812509901 -0.169361069 GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 12961 12961 'Crybb2' mRNA 1 0 0 0.08 0 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005212///structural constituent of eye lens+++GO:0042802///identical protein binding GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0043010///camera-type eye development 12962 12962 'Crybb3' mRNA 25 23 19 0.82 0.69 0.49 0.95 0.75 0.95 0.666666667 0.883333333 33 25 32 22.33333333 30 0.466760091 0.415828645 GO:0005212///structural constituent of eye lens GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 12964 12964 'Cryga' mRNA 26 19 19 3.19 2.32 2.48 0 0.11 0 2.663333333 0.036666667 0 1 0 21.33333333 0.333333333 3.45E-05 -5.905676215 GO:0005212///structural constituent of eye lens GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 12965 12965 'Crygb' mRNA 3 1.66 0 0.35 0.19 0 0 0 0 0.18 0 0 0 0 1.553333333 0 0.489543081 -2.838520661 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005212///structural constituent of eye lens GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0070307///lens fiber cell development+++GO:0070309///lens fiber cell morphogenesis 12966 12966 'Crygc' mRNA 7 3.34 5 0.84 0.4 0.63 0 0 0.11 0.623333333 0.036666667 0 0 1 5.113333333 0.333333333 0.053729982 -3.817823145 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005212///structural constituent of eye lens GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0043010///camera-type eye development 12967 12967 'Crygd' mRNA 7.79 5.89 2.47 0.91 0.69 0.31 0 0.11 0 0.636666667 0.036666667 0 1 0 5.383333333 0.333333333 0.071014306 -3.697130594 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005212///structural constituent of eye lens GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0034614///cellular response to reactive oxygen species+++GO:0043434///response to peptide hormone+++GO:0070306///lens fiber cell differentiation 12968 12968 'Cryge' mRNA 7.21 10.11 3.53 0.58 0.8 0.3 0.1 0 0.07 0.56 0.056666667 1 0 1 6.95 0.666666667 0.050932206 -3.318810348 GO:0005212///structural constituent of eye lens GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception+++GO:0034614///cellular response to reactive oxygen species 12970 12970 'Crygs' mRNA 1 1 8 0.1 0.1 0.85 0.62 0.54 0.55 0.35 0.57 7 6 6 3.333333333 6.333333333 0.557825525 0.872918888 GO:0005212///structural constituent of eye lens GO:0002009///morphogenesis of an epithelium+++GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 12971 12971 'Crym' mRNA 204 204 194 9.84 9.72 9.93 6.47 9.01 8 9.83 7.826666667 154 209 184 200.6666667 182.3333333 0.539519178 -0.147028233 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003714///transcription corepressor activity+++GO:0016491///oxidoreductase activity+++GO:0042562///hormone binding+++GO:0042803///protein homodimerization activity+++GO:0047127///thiomorpholine-carboxylate dehydrogenase activity+++GO:0050661///NADP binding+++GO:0070324///thyroid hormone binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006839///mitochondrial transport+++GO:0007605///sensory perception of sound+++GO:0042403///thyroid hormone metabolic process+++GO:0070327///thyroid hormone transport 12972 12972 'Cryz' mRNA 615.23 630.74 553.01 14.09 14.22 13.39 10.6 9.36 8.07 13.9 9.343333333 525.65 455.39 392.39 599.66 457.81 0.001973719 -0.401465772 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003960///NADPH:quinone reductase activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0050661///NADP binding+++GO:0070402///NADPH binding+++GO:0070404///NADH binding GO:0042178///xenobiotic catabolic process+++GO:0051289///protein homotetramerization 12974 12974 'Cs' mRNA 4283 4523 4437 81.11 84.95 89.89 90.43 83.71 86.23 85.31666667 86.79 5513 4961 5043 4414.333333 5172.333333 0.001069916 0.214980377 00020///Citrate cycle (TCA cycle)+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0004108///citrate (Si)-synthase activity+++GO:0016740///transferase activity+++GO:0036440///citrate synthase activity+++GO:0046912///transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer" GO:0005975///carbohydrate metabolic process+++GO:0006084///acetyl-CoA metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006107///oxaloacetate metabolic process 12977 12977 'Csf1' mRNA 269 316 253 4.51 4.6 4.26 38.41 40.72 38.06 4.456666667 39.06333333 2882 2979 2777 279.3333333 2879.333333 2.78E-304 3.356573748 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04151///PI3K-Akt signaling pathway+++04380///Osteoclast differentiation+++04640///Hematopoietic cell lineage+++04668///TNF signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0048471///perinuclear region of cytoplasm+++GO:1990682///CSF1-CSF1R complex GO:0005125///cytokine activity+++GO:0005157///macrophage colony-stimulating factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0001503///ossification+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002158///osteoclast proliferation+++GO:0002376///immune system process+++GO:0002931///response to ischemia+++GO:0003006///developmental process involved in reproduction+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0030225///macrophage differentiation+++GO:0030278///regulation of ossification+++GO:0030316///osteoclast differentiation+++GO:0030335///positive regulation of cell migration+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032946///positive regulation of mononuclear cell proliferation+++GO:0038145///macrophage colony-stimulating factor signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042476///odontogenesis+++GO:0042488///positive regulation of odontogenesis of dentin-containing tooth+++GO:0045087///innate immune response+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060611///mammary gland fat development+++GO:0060763///mammary duct terminal end bud growth+++GO:0061518///microglial cell proliferation+++GO:1901215///negative regulation of neuron death+++GO:1902228///positive regulation of macrophage colony-stimulating factor signaling pathway+++GO:1904141///positive regulation of microglial cell migration+++GO:1905523///positive regulation of macrophage migration 12978 12978 'Csf1r' mRNA 1635 1737 1703 22.81 23.84 25.21 138.92 133.14 130.47 23.95333333 134.1766667 11459 10728 10423 1691.666667 10870 0 2.670758862 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04151///PI3K-Akt signaling pathway+++04380///Osteoclast differentiation+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:1990682///CSF1-CSF1R complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005011///macrophage colony-stimulating factor receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding+++GO:0019955///cytokine binding+++GO:0042803///protein homodimerization activity GO:0001934///positive regulation of protein phosphorylation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002376///immune system process+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0014005///microglia development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0021542///dentate gyrus development+++GO:0021772///olfactory bulb development+++GO:0021879///forebrain neuron differentiation+++GO:0030097///hemopoiesis+++GO:0030316///osteoclast differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031529///ruffle organization+++GO:0032722///positive regulation of chemokine production+++GO:0032944///regulation of mononuclear cell proliferation+++GO:0033674///positive regulation of kinase activity+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0038145///macrophage colony-stimulating factor signaling pathway+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043066///negative regulation of apoptotic process+++GO:0044794///positive regulation by host of viral process+++GO:0045087///innate immune response+++GO:0045124///regulation of bone resorption+++GO:0045217///cell-cell junction maintenance+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046777///protein autophosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061518///microglial cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071345///cellular response to cytokine stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0120041///positive regulation of macrophage proliferation+++GO:1990138///neuron projection extension+++GO:2000147///positive regulation of cell motility+++GO:2000249///regulation of actin cytoskeleton reorganization 12981 12981 'Csf2' mRNA 0 2 0 0 0.12 0 0.16 0.09 0.39 0.04 0.213333333 3 1 7 0.666666667 3.666666667 0.268650208 2.472482424 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++05131///Shigellosis+++05146///Amoebiasis+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05171///Coronavirus disease - COVID-19+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0005125///cytokine activity+++GO:0005129///granulocyte macrophage colony-stimulating factor receptor binding+++GO:0008083///growth factor activity "GO:0001821///histamine secretion+++GO:0001892///embryonic placenta development+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0030099///myeloid cell differentiation+++GO:0030223///neutrophil differentiation+++GO:0030224///monocyte differentiation+++GO:0030225///macrophage differentiation+++GO:0032747///positive regulation of interleukin-23 production+++GO:0042045///epithelial fluid transport+++GO:0042116///macrophage activation+++GO:0042127///regulation of cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071803///positive regulation of podosome assembly+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0097028///dendritic cell differentiation+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 12982 12982 'Csf2ra' mRNA 852.97 838.87 661.01 16.07 15 12.76 44.63 43.68 42.44 14.61 43.58333333 1921.08 1817.04 1761.76 784.2833333 1833.293333 4.10E-44 1.217953752 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004902///granulocyte colony-stimulating factor receptor activity+++GO:0019955///cytokine binding+++GO:0051916///granulocyte colony-stimulating factor binding GO:0019221///cytokine-mediated signaling pathway+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus 12983 12983 'Csf2rb' mRNA 220.13 221.72 229.97 2.45 2.45 2.73 24.12 20.66 24.19 2.543333333 22.99 2473.65 2068.93 2401.28 223.94 2314.62 1.84E-242 3.359485426 04060///Cytokine-cytokine receptor interaction+++04210///Apoptosis+++04630///JAK-STAT signaling pathway+++05200///Pathways in cancer GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0005515///protein binding GO:0001558///regulation of cell growth+++GO:0019221///cytokine-mediated signaling pathway 12984 12984 'Csf2rb2' mRNA 86.69 97.29 92.05 1.03 1.13 1.14 8.65 7.69 7.78 1.1 8.04 878.34 762.1 765.76 92.01 802.0666667 3.98E-105 3.115798353 04060///Cytokine-cytokine receptor interaction+++04210///Apoptosis+++04630///JAK-STAT signaling pathway+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity GO:0019221///cytokine-mediated signaling pathway 12985 12985 'Csf3' mRNA 1 0 1 0.03 0 0.05 0.27 0.24 0.16 0.026666667 0.223333333 8 6 4 0.666666667 6 0.069351947 3.145331587 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04657///IL-17 signaling pathway+++05144///Malaria+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0071682///endocytic vesicle lumen GO:0005125///cytokine activity+++GO:0005130///granulocyte colony-stimulating factor receptor binding+++GO:0008083///growth factor activity+++GO:0019899///enzyme binding GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030851///granulocyte differentiation+++GO:0032092///positive regulation of protein binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071345///cellular response to cytokine stimulus+++GO:1901215///negative regulation of neuron death+++GO:2000251///positive regulation of actin cytoskeleton reorganization 12986 12986 'Csf3r' mRNA 114.29 139.01 118.05 2.08 2.46 2.3 9.83 9.74 10.45 2.28 10.00666667 633 595.79 665.67 123.7833333 631.4866667 2.34E-60 2.340564365 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030666///endocytic vesicle membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0051916///granulocyte colony-stimulating factor binding GO:0007155///cell adhesion+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0045637///regulation of myeloid cell differentiation+++GO:0097186///amelogenesis 12988 12988 'Csk' mRNA 270 295 267 6.71 7.04 6.95 13.83 13.05 14.11 6.9 13.66333333 648 603 652 277.3333333 634.3333333 6.91E-23 1.182354597 05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070064///proline-rich region binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033673///negative regulation of kinase activity+++GO:0034332///adherens junction organization+++GO:0035556///intracellular signal transduction+++GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045779///negative regulation of bone resorption+++GO:0046777///protein autophosphorylation+++GO:0048709///oligodendrocyte differentiation+++GO:0050765///negative regulation of phagocytosis+++GO:0050863///regulation of T cell activation+++GO:0060368///regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071375///cellular response to peptide hormone stimulus 12994 12994 'Csn3' mRNA 11 7 18 0.83 0.52 1.44 123.38 120 119.56 0.93 120.98 1871 1771 1750 12 1797.333333 1.05E-173 7.214308295 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0007595///lactation+++GO:0050821///protein stabilization 12995 12995 'Csnk2a1' mRNA 954.81 938.11 692.06 11.34 11.21 8.86 13.57 11.2 13.41 10.47 12.72666667 1305.38 1023.57 1228 861.66 1185.65 9.70E-05 0.453092785 03008///Ribosome biogenesis in eukaryotes+++04064///NF-kappa B signaling pathway+++04137///Mitophagy - animal+++04310///Wnt signaling pathway+++04520///Adherens junction+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05162///Measles+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005956///protein kinase CK2 complex+++GO:0016580///Sin3 complex+++GO:0016581///NuRD complex+++GO:0031519///PcG protein complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019888///protein phosphatase regulator activity+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0047485///protein N-terminus binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021987///cerebral cortex development+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030307///positive regulation of cell growth+++GO:0033574///response to testosterone+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0046777///protein autophosphorylation+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0097421///liver regeneration+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1905818///regulation of chromosome separation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 13000 13000 'Csnk2a2' mRNA 308 348 296 4.63 5.33 4.89 5.66 6.26 5.47 4.95 5.796666667 409 403 427 317.3333333 413 0.007926343 0.370324087 03008///Ribosome biogenesis in eukaryotes+++04064///NF-kappa B signaling pathway+++04137///Mitophagy - animal+++04310///Wnt signaling pathway+++04520///Adherens junction+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05162///Measles+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0000785///chromatin+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005956///protein kinase CK2 complex+++GO:0031519///PcG protein complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0047485///protein N-terminus binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021987///cerebral cortex development+++GO:0051726///regulation of cell cycle+++GO:0097421///liver regeneration+++GO:1905818///regulation of chromosome separation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 13001 13001 'Csnk2b' mRNA 1693 1643.28 1578.84 112.34 107.87 111.13 134.21 128.99 132.92 110.4466667 132.04 2317.7 2170.3 2217.42 1638.373333 2235.14 2.42E-10 0.436337063 03008///Ribosome biogenesis in eukaryotes+++04064///NF-kappa B signaling pathway+++04137///Mitophagy - animal+++04310///Wnt signaling pathway+++04520///Adherens junction+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05162///Measles+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005956///protein kinase CK2 complex+++GO:0016363///nuclear matrix+++GO:0031519///PcG protein complex+++GO:0042995///cell projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003682///chromatin binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019887///protein kinase regulator activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0033211///adiponectin-activated signaling pathway+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0050790///regulation of catalytic activity+++GO:0061154///endothelial tube morphogenesis+++GO:0080163///regulation of protein serine/threonine phosphatase activity+++GO:0099170///postsynaptic modulation of chemical synaptic transmission 13002 13002 'Dnajc5' mRNA 2556 2920 2832 31.87 35.68 37.45 34.42 32.74 34.39 35 33.85 3173 2946 3067 2769.333333 3062 0.11338009 0.131335074 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0042470///melanosome+++GO:0042584///chromaffin granule membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098793///presynapse+++GO:0098993///anchored component of synaptic vesicle membrane GO:0005515///protein binding+++GO:0043008///ATP-dependent protein binding GO:0043524///negative regulation of neuron apoptotic process+++GO:0061077///chaperone-mediated protein folding+++GO:0098693///regulation of synaptic vesicle cycle 13003 13003 'Vcan' mRNA 86 107 89 0.53 0.53 0.51 1.55 1.09 1.32 0.523333333 1.32 281 224 270 94 258.3333333 1.82E-13 1.446757962 04514///Cell adhesion molecules GO:0001750///photoreceptor outer segment+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0033165///interphotoreceptor matrix+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0072534///perineuronal net GO:0005509///calcium ion binding+++GO:0005540///hyaluronic acid binding+++GO:0019903///protein phosphatase binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030246///carbohydrate binding GO:0001501///skeletal system development+++GO:0001657///ureteric bud development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0008347///glial cell migration+++GO:0043666///regulation of phosphoprotein phosphatase activity 13004 13004 'Ncan' mRNA 9 15 18 0.07 0.11 0.14 0.19 0.22 0.27 0.106666667 0.226666667 29 34 41 14 34.66666667 0.018403861 1.291510544 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0072534///perineuronal net GO:0005509///calcium ion binding+++GO:0005540///hyaluronic acid binding+++GO:0030246///carbohydrate binding GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development+++GO:0051823///regulation of synapse structural plasticity 13006 13006 'Smc3' mRNA 1895 2008 2010 20.9 21.77 23.51 18.75 18.55 18.05 22.06 18.45 1958 1892 1825 1971 1891.666667 0.43631411 -0.072662897 04110///Cell cycle+++04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000800///lateral element+++GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0008278///cohesin complex+++GO:0016363///nuclear matrix+++GO:0030893///meiotic cohesin complex+++GO:0034990///nuclear mitotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex+++GO:0097431///mitotic spindle pole" GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0036033///mediator complex binding+++GO:0046982///protein heterodimerization activity+++GO:0048487///beta-tubulin binding+++GO:0061775///cohesin ATPase activity+++GO:0070840///dynein complex binding GO:0006275///regulation of DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0019827///stem cell population maintenance+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly 13007 13007 'Csrp1' mRNA 3417 3520 1088 109.24 110.82 36.87 34.28 53.02 48.9 85.64333333 45.4 1235 1863 1704 2675 1600.666667 0.228672144 -0.724681152 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0042805///actinin binding+++GO:0046872///metal ion binding GO:0030036///actin cytoskeleton organization+++GO:0045214///sarcomere organization+++GO:0060537///muscle tissue development 13008 13008 'Csrp2' mRNA 279 275 304 20.7 20.2 23.93 58.1 51.12 50.29 21.61 53.17 897 769 750 286 805.3333333 3.19E-33 1.478056361 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030018///Z disc GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0042805///actinin binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0045214///sarcomere organization+++GO:0060537///muscle tissue development 13010 13010 'Cst3' mRNA 30854 30946 30733 2644.8 2629.56 2795.7 2841.59 2908.56 2827.84 2690.02 2859.33 37941 37815 36453 30844.33333 37403 4.25E-07 0.265521489 04970///Salivary secretion GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0031965///nuclear membrane+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043292///contractile fiber+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0001540///amyloid-beta binding+++GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding "GO:0001654///eye development+++GO:0001666///response to hypoxia+++GO:0001775///cell activation+++GO:0006915///apoptotic process+++GO:0006952///defense response+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0007431///salivary gland development+++GO:0007566///embryo implantation+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009636///response to toxic substance+++GO:0009743///response to carbohydrate+++GO:0010035///response to inorganic substance+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0014070///response to organic cyclic compound+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0034599///cellular response to oxidative stress+++GO:0042493///response to drug+++GO:0042747///circadian sleep/wake cycle, REM sleep+++GO:0043067///regulation of programmed cell death+++GO:0045740///positive regulation of DNA replication+++GO:0045861///negative regulation of proteolysis+++GO:0048678///response to axon injury+++GO:0060009///Sertoli cell development+++GO:0060311///negative regulation of elastin catabolic process+++GO:0060548///negative regulation of cell death+++GO:0070301///cellular response to hydrogen peroxide+++GO:0097435///supramolecular fiber organization" 13011 13011 'Cst7' mRNA 12 3 5 0.78 0.19 0.35 2.55 2.74 3.64 0.44 2.976666667 45 47 62 6.666666667 51.33333333 1.80E-07 2.936750222 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0042803///protein homodimerization activity GO:0006955///immune response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0031643///positive regulation of myelination+++GO:0097340///inhibition of cysteine-type endopeptidase activity+++GO:1903979///negative regulation of microglial cell activation 13012 13012 'Cst8' mRNA 1 1 1 0.1 0.1 0.11 0 0 0 0.103333333 0 0 0 0 1 0 0.568344116 -2.455252046 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0009986///cell surface GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 13014 13014 'Cstb' mRNA 1004 967 1051 127.31 122.09 141.47 539.08 619.27 561.23 130.29 573.1933333 4850 5415 4866 1007.333333 5043.666667 1.02E-177 2.311114168 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0008344///adult locomotory behavior+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0045861///negative regulation of proteolysis 13016 13016 'Ctbp1' mRNA 1127 1130 746 25.79 26.24 19.37 21.32 20 22.36 23.8 21.22666667 1013 903 1020 1001 978.6666667 0.839303607 -0.036528819 04310///Wnt signaling pathway+++04330///Notch signaling pathway+++05200///Pathways in cancer+++05220///Chronic myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex+++GO:0098793///presynapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse "GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051287///NAD binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006342///chromatin silencing+++GO:0030154///cell differentiation+++GO:0031065///positive regulation of histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0035067///negative regulation of histone acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050872///white fat cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0090241///negative regulation of histone H4 acetylation+++GO:0099526///presynapse to nucleus signaling pathway" 13017 13017 'Ctbp2' mRNA 2382.78 2453.7 1874.7 29.64 30.66 26.08 15.34 13.32 15.46 28.79333333 14.70666667 1500.43 1226.91 1407.47 2237.06 1378.27 6.96E-15 -0.706960029 04310///Wnt signaling pathway+++04330///Notch signaling pathway+++05200///Pathways in cancer+++05220///Chronic myeloid leukemia GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0097470///ribbon synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099523///presynaptic cytosol "GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042974///retinoic acid receptor binding+++GO:0044877///protein-containing complex binding+++GO:0051287///NAD binding+++GO:0098882///structural constituent of presynaptic active zone" "GO:0016081///synaptic vesicle docking+++GO:0030154///cell differentiation+++GO:0035563///positive regulation of chromatin binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0050872///white fat cell differentiation+++GO:1990830///cellular response to leukemia inhibitory factor" 13018 13018 'Ctcf' mRNA 851.15 805.88 799.43 8.81 7.91 8.42 7.91 7.69 8.17 8.38 7.923333333 927.21 839.59 909.17 818.82 891.99 0.312936134 0.111373393 "GO:0000775///chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043035///chromatin insulator sequence binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007059///chromosome segregation+++GO:0008285///negative regulation of cell proliferation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010216///maintenance of DNA methylation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016584///nucleosome positioning+++GO:0031060///regulation of histone methylation+++GO:0035065///regulation of histone acetylation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0040030///regulation of molecular function, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0071514///genetic imprinting+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 13019 13019 'Ctf1' mRNA 857 909 112 36.89 38.6 5.12 3.69 11.84 12.5 26.87 9.343333333 99 308 322 626 243 0.216328405 -1.333683366 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005146///leukemia inhibitory factor receptor binding GO:0007166///cell surface receptor signaling pathway+++GO:0007399///nervous system development+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0048666///neuron development+++GO:0048861///leukemia inhibitory factor signaling pathway 13024 13024 'Ctla2a' mRNA 275.5 226.53 243.68 12.07 9.86 11.36 36.32 40.13 37 11.09666667 37.81666667 953.12 1026.97 939.05 248.57 973.0466667 2.96E-61 1.960317016 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0030425///dendrite GO:0004197///cysteine-type endopeptidase activity GO:0010955///negative regulation of protein processing+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0051603///proteolysis involved in cellular protein catabolic process 13025 13025 'Ctla2b' mRNA 30 23 18 1.89 1.33 1.29 19.74 17.42 17.42 1.503333333 18.19333333 355 322 314.01 23.66666667 330.3366667 1.19E-54 3.793479223 GO:0005615///extracellular space+++GO:0005764///lysosome GO:0004197///cysteine-type endopeptidase activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005515///protein binding GO:0010951///negative regulation of endopeptidase activity+++GO:0051603///proteolysis involved in cellular protein catabolic process 13026 13026 'Pcyt1a' mRNA 1209 1085 1206 13.48 11.89 14.23 15.18 14.25 14.81 13.2 14.74666667 1569 1442 1482 1166.666667 1497.666667 1.75E-04 0.345667369 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042587///glycogen granule GO:0003824///catalytic activity+++GO:0004105///choline-phosphate cytidylyltransferase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006629///lipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0009058///biosynthetic process 13030 13030 'Ctsb' mRNA 18423.77 19611.3 18876.1 490.45 507.46 521.52 3066.89 3132.34 3061.86 506.4766667 3087.03 129213.77 130275.9 123970.37 18970.39 127820.0133 0 2.740073839 04140///Autophagy - animal+++04142///Lysosome+++04210///Apoptosis+++04612///Antigen processing and presentation+++04621///NOD-like receptor signaling pathway+++04924///Renin secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0030984///kininogen binding+++GO:0042277///peptide binding+++GO:0043394///proteoglycan binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation+++GO:0030574///collagen catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0046697///decidualization+++GO:0046718///viral entry into host cell+++GO:0050790///regulation of catalytic activity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060548///negative regulation of cell death+++GO:0097067///cellular response to thyroid hormone stimulus 13032 13032 'Ctsc' mRNA 1367 1535 1441 24.32 26.6 26.68 211.98 219.63 211.05 25.86666667 214.22 13424 13628 12953 1447.666667 13335 0 3.191765741 04142///Lysosome+++04210///Apoptosis GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0004197///cysteine-type endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0016787///hydrolase activity+++GO:0019902///phosphatase binding+++GO:0031404///chloride ion binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0051087///chaperone binding GO:0001913///T cell mediated cytotoxicity+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007568///aging+++GO:0010033///response to organic substance+++GO:0031642///negative regulation of myelination+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:1903980///positive regulation of microglial cell activation+++GO:2001235///positive regulation of apoptotic signaling pathway 13033 13033 'Ctsd' mRNA 21986 22979 21607 656.09 675.66 684.02 3404.32 3407.75 3358.06 671.9233333 3390.043333 131141 128145 125197 22190.66667 128161 0 2.51818901 04071///Sphingolipid signaling pathway+++04140///Autophagy - animal+++04142///Lysosome+++04210///Apoptosis+++04915///Estrogen signaling pathway+++05152///Tuberculosis+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0010008///endosome membrane+++GO:0042470///melanosome+++GO:0045121///membrane raft+++GO:0062023///collagen-containing extracellular matrix GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0070001///aspartic-type peptidase activity GO:0000045///autophagosome assembly+++GO:0006508///proteolysis+++GO:0042159///lipoprotein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0070201///regulation of establishment of protein localization 13034 13034 'Ctse' mRNA 34 33 29 0.91 0.87 0.82 11.51 11.1 11.03 0.866666667 11.21333333 496 467 460 32 474.3333333 2.33E-80 3.879096753 04142///Lysosome GO:0005768///endosome GO:0004190///aspartic-type endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0016540///protein autoprocessing+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II 13035 13035 'Ctsg' mRNA 3 2 8 0.19 0.13 0.54 0.39 0.52 0 0.286666667 0.303333333 7 9 0 4.333333333 5.333333333 0.873788675 0.259770893 04080///Neuroactive ligand-receptor interaction+++04142///Lysosome+++04613///Neutrophil extracellular trap formation+++04614///Renin-angiotensin system+++05146///Amoebiasis+++05322///Systemic lupus erythematosus GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006468///protein phosphorylation+++GO:0006508///proteolysis+++GO:0019731///antibacterial humoral response+++GO:0032496///response to lipopolysaccharide+++GO:0050778///positive regulation of immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0070946///neutrophil mediated killing of gram-positive bacterium+++GO:0071222///cellular response to lipopolysaccharide 13036 13036 'Ctsh' mRNA 701 734 791 25.33 26.46 30.96 119.53 118.02 115.34 27.58333333 117.63 3784 3659 3534 742 3659 1.44E-178 2.287547255 04142///Lysosome+++04210///Apoptosis GO:0001520///outer dense fiber+++GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097208///alveolar lamellar body GO:0004175///endopeptidase activity+++GO:0004177///aminopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0016787///hydrolase activity+++GO:0030108///HLA-A specific activating MHC class I receptor activity+++GO:0030984///kininogen binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding+++GO:0070324///thyroid hormone binding GO:0001656///metanephros development+++GO:0001913///T cell mediated cytotoxicity+++GO:0002250///adaptive immune response+++GO:0002764///immune response-regulating signaling pathway+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010813///neuropeptide catabolic process+++GO:0010815///bradykinin catabolic process+++GO:0010952///positive regulation of peptidase activity+++GO:0030335///positive regulation of cell migration+++GO:0031638///zymogen activation+++GO:0031648///protein destabilization+++GO:0032526///response to retinoic acid+++GO:0033619///membrane protein proteolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0043129///surfactant homeostasis+++GO:0045766///positive regulation of angiogenesis+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060448///dichotomous subdivision of terminal units involved in lung branching+++GO:0070371///ERK1 and ERK2 cascade+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2001235///positive regulation of apoptotic signaling pathway 13038 13038 'Ctsk' mRNA 172 171 152 6.37 6.24 5.97 27.85 26.76 25.05 6.193333333 26.55333333 864 810 752 165 808.6666667 4.79E-74 2.282320471 04142///Lysosome+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001968///fibronectin binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0043394///proteoglycan binding GO:0001957///intramembranous ossification+++GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation+++GO:0006955///immune response+++GO:0030574///collagen catabolic process+++GO:0045453///bone resorption+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0061037///negative regulation of cartilage development 13039 13039 'Ctsl' mRNA 7780.89 8091.83 7723.23 267.42 274.08 280.85 730.55 725.96 731.96 274.1166667 729.49 24433.88 23654.12 23632.07 7865.316667 23906.69 6.86E-241 1.591859047 04140///Autophagy - animal+++04142///Lysosome+++04145///Phagosome+++04210///Apoptosis+++04612///Antigen processing and presentation+++05205///Proteoglycans in cancer+++05323///Rheumatoid arthritis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005771///multivesicular body+++GO:0005773///vacuole+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0042583///chromaffin granule+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0004175///endopeptidase activity+++GO:0004177///aminopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016807///cysteine-type carboxypeptidase activity+++GO:0030984///kininogen binding+++GO:0042277///peptide binding+++GO:0042393///histone binding+++GO:0043394///proteoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0097655///serpin family protein binding "GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation+++GO:0006955///immune response+++GO:0007154///cell communication+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0010259///multicellular organism aging+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0016540///protein autoprocessing+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0021675///nerve development+++GO:0030574///collagen catabolic process+++GO:0031069///hair follicle morphogenesis+++GO:0031638///zymogen activation+++GO:0034230///enkephalin processing+++GO:0034698///response to gonadotropin+++GO:0039654///fusion of virus membrane with host endosome membrane+++GO:0042637///catagen+++GO:0043373///CD4-positive, alpha-beta T cell lineage commitment+++GO:0046697///decidualization+++GO:0046718///viral entry into host cell+++GO:0048002///antigen processing and presentation of peptide antigen+++GO:0048102///autophagic cell death+++GO:0051384///response to glucocorticoid+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060008///Sertoli cell differentiation+++GO:0060309///elastin catabolic process+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:2000249///regulation of actin cytoskeleton reorganization" 13040 13040 'Ctss' mRNA 1515 1571 1480 67.03 68.59 69.47 982.59 994.42 978.11 68.36333333 985.04 25503 25178 24554 1522 25078.33333 0 4.031076784 04142///Lysosome+++04145///Phagosome+++04210///Apoptosis+++04612///Antigen processing and presentation+++05152///Tuberculosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031905///early endosome lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle GO:0001968///fibronectin binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0043236///laminin binding+++GO:0043394///proteoglycan binding GO:0002250///adaptive immune response+++GO:0006508///proteolysis+++GO:0006955///immune response+++GO:0010447///response to acidic pH+++GO:0016485///protein processing+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030574///collagen catabolic process+++GO:0034769///basement membrane disassembly+++GO:0045453///bone resorption+++GO:0048002///antigen processing and presentation of peptide antigen+++GO:0050729///positive regulation of inflammatory response+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0051930///regulation of sensory perception of pain+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2001259///positive regulation of cation channel activity 13041 13041 'Ctsw' mRNA 19 21 24 0.85 0.86 1.19 2.81 2.51 2.35 0.966666667 2.556666667 78 68 63 21.33333333 69.66666667 8.88E-06 1.691364964 04142///Lysosome+++04210///Apoptosis GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0051603///proteolysis involved in cellular protein catabolic process 13043 13043 'Cttn' mRNA 2922 2881 2514 50.76 49.14 46.38 72.16 69.53 72.04 48.76 71.24333333 4806 4519 4644 2772.333333 4656.333333 2.01E-36 0.738338052 04530///Tight junction+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05205///Proteoglycans in cancer GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030427///site of polarized growth+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:1990023///mitotic spindle midzone GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0051015///actin filament binding+++GO:0070064///proline-rich region binding+++GO:0071933///Arp2/3 complex binding "GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0030041///actin filament polymerization+++GO:0030516///regulation of axon extension+++GO:0030833///regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0048041///focal adhesion assembly+++GO:0048812///neuron projection morphogenesis+++GO:0048870///cell motility+++GO:0050921///positive regulation of chemotaxis+++GO:0060491///regulation of cell projection assembly+++GO:0097062///dendritic spine maintenance+++GO:0097581///lamellipodium organization+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:1903146///regulation of autophagy of mitochondrion+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 13046 13046 'Celf1' mRNA 2525 2751 1387 20.14 21.48 10.89 13.49 15.89 15.02 17.50333333 14.8 2063 2315 2197 2221 2191.666667 0.972726909 -0.014967068 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0097356///perinucleolar compartment+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031369///translation initiation factor binding+++GO:0036002///pre-mRNA binding+++GO:0042835///BRE binding+++GO:0048027///mRNA 5'-UTR binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0007286///spermatid development+++GO:0008285///negative regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0016441///posttranscriptional gene silencing+++GO:0017148///negative regulation of translation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021987///cerebral cortex development+++GO:0040018///positive regulation of multicellular organism growth+++GO:0043484///regulation of RNA splicing+++GO:0050727///regulation of inflammatory response+++GO:0051726///regulation of cell cycle+++GO:0061157///mRNA destabilization+++GO:0071158///positive regulation of cell cycle arrest" 13047 13047 'Cux1' mRNA 2580 2577 1858 31.66 30.66 25.61 21.32 20.43 21.27 29.31 21.00666667 1831 1749 1847 2338.333333 1809 8.32E-05 -0.375388989 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0043005///neuron projection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000301///retrograde transport, vesicle recycling within Golgi+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0007275///multicellular organism development+++GO:0030324///lung development+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0050775///positive regulation of dendrite morphogenesis" 13048 13048 'Cux2' mRNA 327 353 298 2.45 2.56 2.35 0.49 0.41 0.34 2.453333333 0.413333333 78 62 51 326 63.66666667 7.80E-33 -2.367356665 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007614///short-term memory+++GO:0010628///positive regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050890///cognition+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071310///cellular response to organic substance+++GO:2000463///positive regulation of excitatory postsynaptic potential" 13051 13051 'Cx3cr1' mRNA 491 518 480 7.09 7.35 7.35 26.51 26.19 26.06 7.263333333 26.25333333 2114 2040 2013 496.3333333 2055.666667 2.51E-139 2.038929609 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032809///neuronal cell body membrane+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0097447///dendritic tree GO:0004896///cytokine receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016495///C-X3-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0019960///C-X3-C chemokine binding+++GO:0031737///CX3C chemokine receptor binding "GO:0001774///microglial cell activation+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002250///adaptive immune response+++GO:0002282///microglial cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002881///negative regulation of chronic inflammatory response to non-antigenic stimulus+++GO:0002931///response to ischemia+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007420///brain development+++GO:0007613///memory+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019722///calcium-mediated signaling+++GO:0021626///central nervous system maturation+++GO:0021795///cerebral cortex cell migration+++GO:0030336///negative regulation of cell migration+++GO:0030595///leukocyte chemotaxis+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0035176///social behavior+++GO:0035425///autocrine signaling+++GO:0045087///innate immune response+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0048246///macrophage chemotaxis+++GO:0048874///host-mediated regulation of intestinal microbiota composition+++GO:0050769///positive regulation of neurogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050901///leukocyte tethering or rolling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060074///synapse maturation+++GO:0060326///cell chemotaxis+++GO:0061760///antifungal innate immune response+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0098883///synapse pruning+++GO:0110091///negative regulation of hippocampal neuron apoptotic process+++GO:0150090///multiple spine synapse organization, single dendrite+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1904141///positive regulation of microglial cell migration+++GO:1904150///negative regulation of microglial cell mediated cytotoxicity+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 13052 13052 'Cxadr' mRNA 3347 3619 2868 42.75 46.41 40.56 33.45 29.83 32.57 43.24 31.95 2880 2411 2702 3278 2664.333333 8.62E-05 -0.308166879 05416///Viral myocarditis GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0071253///connexin binding+++GO:0086082///cell adhesive protein binding involved in AV node cell-bundle of His cell communication GO:0007005///mitochondrion organization+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007507///heart development+++GO:0008354///germ cell migration+++GO:0010669///epithelial structure maintenance+++GO:0030593///neutrophil chemotaxis+++GO:0031532///actin cytoskeleton reorganization+++GO:0034109///homotypic cell-cell adhesion+++GO:0045216///cell-cell junction organization+++GO:0046629///gamma-delta T cell activation+++GO:0048739///cardiac muscle fiber development+++GO:0051607///defense response to virus+++GO:0055013///cardiac muscle cell development+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0070633///transepithelial transport+++GO:0086067///AV node cell to bundle of His cell communication+++GO:0086072///AV node cell-bundle of His cell adhesion involved in cell communication+++GO:0098609///cell-cell adhesion+++GO:0098904///regulation of AV node cell action potential 13056 13056 'Cyb561' mRNA 2528 2786 2665 54.03 59.36 60.39 39.52 40.88 40.95 57.92666667 40.45 2104 2126 2108 2659.666667 2112.666667 2.62E-06 -0.344350725 GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042584///chromaffin granule membrane GO:0000293///ferric-chelate reductase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006879///cellular iron ion homeostasis+++GO:0022900///electron transport chain 13057 13057 'Cyba' mRNA 1809 1796 1784 165.94 163.39 173.57 714.73 833.62 712.45 167.6333333 753.6 8919 10119 8580 1796.333333 9206 2.54E-218 2.346398287 04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04670///Leukocyte transendothelial migration+++05020///Prion disease+++05140///Leishmaniasis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0043020///NADPH oxidase complex+++GO:0043025///neuronal cell body+++GO:0097038///perinuclear endoplasmic reticulum GO:0005515///protein binding+++GO:0009055///electron transfer activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0017124///SH3 domain binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0001666///response to hypoxia+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0003106///negative regulation of glomerular filtration by angiotensin+++GO:0006801///superoxide metabolic process+++GO:0006954///inflammatory response+++GO:0014823///response to activity+++GO:0014895///smooth muscle hypertrophy+++GO:0017004///cytochrome complex assembly+++GO:0022900///electron transport chain+++GO:0030307///positive regulation of cell growth+++GO:0031667///response to nutrient levels+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0042493///response to drug+++GO:0042554///superoxide anion generation+++GO:0045087///innate immune response+++GO:0045730///respiratory burst+++GO:0045777///positive regulation of blood pressure+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0050766///positive regulation of phagocytosis+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0070257///positive regulation of mucus secretion+++GO:0070555///response to interleukin-1+++GO:0071230///cellular response to amino acid stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0071310///cellular response to organic substance+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0071480///cellular response to gamma radiation+++GO:0072593///reactive oxygen species metabolic process+++GO:1900426///positive regulation of defense response to bacterium+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904044///response to aldosterone+++GO:1904385///cellular response to angiotensin+++GO:1904845///cellular response to L-glutamine 13058 13058 'Cybb' mRNA 297 298 250 3.47 3.43 3.09 43.71 41.69 43.06 3.33 42.82 4301 4008 4105 281.6666667 4138 0 3.866764785 04066///HIF-1 signaling pathway+++04145///Phagosome+++04216///Ferroptosis+++04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04670///Leukocyte transendothelial migration+++04933///AGE-RAGE signaling pathway in diabetic complications+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05140///Leishmaniasis+++05171///Coronavirus disease - COVID-19+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043020///NADPH oxidase complex+++GO:0043025///neuronal cell body+++GO:0045335///phagocytic vesicle+++GO:0097038///perinuclear endoplasmic reticulum GO:0005244///voltage-gated ion channel activity+++GO:0005515///protein binding+++GO:0009055///electron transfer activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050660///flavin adenine dinucleotide binding GO:0006801///superoxide metabolic process+++GO:0006811///ion transport+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0007584///response to nutrient+++GO:0022900///electron transport chain+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042493///response to drug+++GO:0042554///superoxide anion generation+++GO:0045087///innate immune response+++GO:0045730///respiratory burst+++GO:0045766///positive regulation of angiogenesis+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0071276///cellular response to cadmium ion+++GO:0071361///cellular response to ethanol+++GO:0071456///cellular response to hypoxia+++GO:0097411///hypoxia-inducible factor-1alpha signaling pathway+++GO:1904044///response to aldosterone+++GO:1904845///cellular response to L-glutamine+++GO:1990776///response to angiotensin 13063 13063 'Cycs' mRNA 3389.91 3578.48 3389.08 58.84 61.12 62.4 88.63 99.2 87.81 60.78666667 91.88 5875.98 6423.45 5637.09 3452.49 5978.84 5.33E-30 0.781349437 00190///Oxidative phosphorylation+++01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05222///Small cell lung cancer+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain GO:0009055///electron transfer activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding "GO:0002931///response to ischemia+++GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0006915///apoptotic process+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0022900///electron transport chain+++GO:0042743///hydrogen peroxide metabolic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043393///regulation of protein binding+++GO:1901857///positive regulation of cellular respiration" 13067 13067 'Cyct' mRNA 1 0 2 0.11 0 0.18 0.2 0.2 0.1 0.096666667 0.166666667 2 2 1 1 1.666666667 0.811835505 0.69439629 00190///Oxidative phosphorylation+++01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05222///Small cell lung cancer+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0070469///respiratory chain GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0006915///apoptotic process+++GO:0022900///electron transport chain+++GO:0042743///hydrogen peroxide metabolic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 13070 13070 'Cyp11a1' mRNA 32 24 12 0.63 0.47 0.25 0.52 0.49 0.68 0.45 0.563333333 30 28 37 22.66666667 31.66666667 0.415677696 0.483439999 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0030061///mitochondrial crista+++GO:0043204///perikaryon "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008386///cholesterol monooxygenase (side-chain-cleaving) activity+++GO:0015485///cholesterol binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006704///glucocorticoid biosynthetic process+++GO:0007617///mating behavior+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0034650///cortisol metabolic process+++GO:0042542///response to hydrogen peroxide+++GO:0071375///cellular response to peptide hormone stimulus 13074 13074 'Cyp17a1' mRNA 7 3 6 0.22 0.09 0.2 0.08 0 0 0.17 0.026666667 3 0 0 5.333333333 1 0.169801597 -2.452222362 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04917///Prolactin signaling pathway+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004508///steroid 17-alpha-monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016829///lyase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0047442///17-alpha-hydroxyprogesterone aldolase activity" GO:0006694///steroid biosynthetic process+++GO:0006704///glucocorticoid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0042446///hormone biosynthetic process+++GO:0042448///progesterone metabolic process+++GO:0090031///positive regulation of steroid hormone biosynthetic process 13075 13075 'Cyp19a1' mRNA 1 2 0 0.02 0.05 0 0.06 0 0 0.023333333 0.02 3 0 0 1 1 0.999123543 -0.00436044 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0045202///synapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001091///RNA polymerase II basal transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004497///monooxygenase activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005496///steroid binding+++GO:0005497///androgen binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0020037///heme binding+++GO:0032553///ribonucleotide binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051117///ATPase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070330///aromatase activity+++GO:0070974///POU domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0002677///negative regulation of chronic inflammatory response+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0003382///epithelial cell morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006703///estrogen biosynthetic process+++GO:0006710///androgen catabolic process+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007620///copulation+++GO:0008049///male courtship behavior+++GO:0008207///C21-steroid hormone metabolic process+++GO:0008209///androgen metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009566///fertilization+++GO:0009987///cellular process+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0014734///skeletal muscle hypertrophy+++GO:0019098///reproductive behavior+++GO:0019102///male somatic sex determination+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0030521///androgen receptor signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0030540///female genitalia development+++GO:0030879///mammary gland development+++GO:0032355///response to estradiol+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0033327///Leydig cell differentiation+++GO:0035264///multicellular organism growth+++GO:0042327///positive regulation of phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045597///positive regulation of cell differentiation+++GO:0045720///negative regulation of integrin biosynthetic process+++GO:0045726///positive regulation of integrin biosynthetic process+++GO:0045779///negative regulation of bone resorption+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0046661///male sex differentiation+++GO:0048608///reproductive structure development+++GO:0048638///regulation of developmental growth+++GO:0048645///animal organ formation+++GO:0048808///male genitalia morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050803///regulation of synapse structure or activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060065///uterus development+++GO:0060406///positive regulation of penile erection+++GO:0060520///activation of prostate induction by androgen receptor signaling pathway+++GO:0060571///morphogenesis of an epithelial fold+++GO:0060599///lateral sprouting involved in mammary gland duct morphogenesis+++GO:0060685///regulation of prostatic bud formation+++GO:0060736///prostate gland growth+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0060749///mammary gland alveolus development+++GO:0060769///positive regulation of epithelial cell proliferation involved in prostate gland development+++GO:0061370///testosterone biosynthetic process+++GO:0061458///reproductive system development+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0072520///seminiferous tubule development+++GO:0097720///calcineurin-mediated signaling+++GO:1903076///regulation of protein localization to plasma membrane+++GO:2000866///positive regulation of estradiol secretion+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 13076 13076 'Cyp1a1' mRNA 2 6 6.14 0.04 0.13 0.14 0.24 0.25 0.17 0.103333333 0.22 13 13 9 4.713333333 11.66666667 0.184564919 1.304049521 00140///Steroid hormone biosynthesis+++00380///Tryptophan metabolism+++00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++04913///Ovarian steroidogenesis+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016679///oxidoreductase activity, acting on diphenols and related substances as donors+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016711///flavonoid 3'-monooxygenase activity+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030544///Hsp70 protein binding+++GO:0032451///demethylase activity+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding+++GO:0070330///aromatase activity+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0001666///response to hypoxia+++GO:0001889///liver development+++GO:0002933///lipid hydroxylation+++GO:0006306///DNA methylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006706///steroid catabolic process+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0007568///aging+++GO:0008202///steroid metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008283///cell proliferation+++GO:0009308///amine metabolic process+++GO:0009403///toxin biosynthetic process+++GO:0009404///toxin metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0009611///response to wounding+++GO:0009615///response to virus+++GO:0009624///response to nematode+++GO:0009635///response to herbicide+++GO:0009636///response to toxic substance+++GO:0009804///coumarin metabolic process+++GO:0009812///flavonoid metabolic process+++GO:0009820///alkaloid metabolic process+++GO:0010033///response to organic substance+++GO:0010041///response to iron(III) ion+++GO:0014070///response to organic cyclic compound+++GO:0016098///monoterpenoid metabolic process+++GO:0017143///insecticide metabolic process+++GO:0017144///drug metabolic process+++GO:0018894///dibenzo-p-dioxin metabolic process+++GO:0019341///dibenzo-p-dioxin catabolic process+++GO:0032094///response to food+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032502///developmental process+++GO:0032787///monocarboxylic acid metabolic process+++GO:0033189///response to vitamin A+++GO:0035902///response to immobilization stress+++GO:0042493///response to drug+++GO:0042572///retinol metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0043010///camera-type eye development+++GO:0046483///heterocycle metabolic process+++GO:0046677///response to antibiotic+++GO:0046685///response to arsenic-containing substance+++GO:0048565///digestive tract development+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0055093///response to hyperoxia+++GO:0060137///maternal process involved in parturition+++GO:0070365///hepatocyte differentiation+++GO:0070988///demethylation+++GO:0070989///oxidative demethylation+++GO:0071280///cellular response to copper ion+++GO:0071407///cellular response to organic cyclic compound+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 13077 13077 'Cyp1a2' mRNA 18 29 25.86 0.55 0.87 0.83 0.03 0.11 0.08 0.75 0.073333333 1 4 3 24.28666667 2.666666667 1.28E-04 -3.177975236 00140///Steroid hormone biosynthesis+++00232///Caffeine metabolism+++00380///Tryptophan metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016679///oxidoreductase activity, acting on diphenols and related substances as donors+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016711///flavonoid 3'-monooxygenase activity+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030544///Hsp70 protein binding+++GO:0032451///demethylase activity+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding+++GO:0070330///aromatase activity+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0001666///response to hypoxia+++GO:0002933///lipid hydroxylation+++GO:0006306///DNA methylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006706///steroid catabolic process+++GO:0006725///cellular aromatic compound metabolic process+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0007568///aging+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008283///cell proliferation+++GO:0009403///toxin biosynthetic process+++GO:0009404///toxin metabolic process+++GO:0009611///response to wounding+++GO:0009615///response to virus+++GO:0009624///response to nematode+++GO:0009635///response to herbicide+++GO:0009791///post-embryonic development+++GO:0009804///coumarin metabolic process+++GO:0009812///flavonoid metabolic process+++GO:0009820///alkaloid metabolic process+++GO:0010033///response to organic substance+++GO:0010041///response to iron(III) ion+++GO:0010468///regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0016098///monoterpenoid metabolic process+++GO:0017143///insecticide metabolic process+++GO:0017144///drug metabolic process+++GO:0018894///dibenzo-p-dioxin metabolic process+++GO:0019341///dibenzo-p-dioxin catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0030324///lung development+++GO:0032094///response to food+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032787///monocarboxylic acid metabolic process+++GO:0033189///response to vitamin A+++GO:0035902///response to immobilization stress+++GO:0042178///xenobiotic catabolic process+++GO:0042493///response to drug+++GO:0042572///retinol metabolic process+++GO:0042737///drug catabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0043010///camera-type eye development+++GO:0045333///cellular respiration+++GO:0046483///heterocycle metabolic process+++GO:0046677///response to antibiotic+++GO:0046685///response to arsenic-containing substance+++GO:0048565///digestive tract development+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0055093///response to hyperoxia+++GO:0060137///maternal process involved in parturition+++GO:0070365///hepatocyte differentiation+++GO:0070989///oxidative demethylation+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071407///cellular response to organic cyclic compound+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 13078 13078 'Cyp1b1' mRNA 735 788 830 8.08 8.03 9.71 26.13 26.33 24.16 8.606666667 25.54 2792 2711 2560 784.3333333 2687.666667 4.10E-97 1.762555068 00140///Steroid hormone biosynthesis+++00380///Tryptophan metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++04913///Ovarian steroidogenesis+++05204///Chemical carcinogenesis - DNA adducts+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016829///lyase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity" GO:0001525///angiogenesis+++GO:0002930///trabecular meshwork development+++GO:0006304///DNA modification+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006725///cellular aromatic compound metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0007155///cell adhesion+++GO:0008202///steroid metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009404///toxin metabolic process+++GO:0009636///response to toxic substance+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0018894///dibenzo-p-dioxin metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0030199///collagen fibril organization+++GO:0030336///negative regulation of cell migration+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0042537///benzene-containing compound metabolic process+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045727///positive regulation of translation+++GO:0045766///positive regulation of angiogenesis+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046466///membrane lipid catabolic process+++GO:0048514///blood vessel morphogenesis+++GO:0061298///retina vasculature development in camera-type eye+++GO:0061304///retinal blood vessel morphogenesis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071407///cellular response to organic cyclic compound+++GO:0071603///endothelial cell-cell adhesion+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000573///positive regulation of DNA biosynthetic process 13079 13079 'Cyp21a1' mRNA 0 1 1 0 0.03 0.03 0.34 0.48 0.67 0.02 0.496666667 13 18 25 0.666666667 18.66666667 2.76E-04 4.797360357 00140///Steroid hormone biosynthesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004509///steroid 21-monooxygenase activity+++GO:0005496///steroid binding+++GO:0005506///iron ion binding+++GO:0008289///lipid binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0103069///17-hydroxyprogesterone 21-hydroxylase activity" GO:0006694///steroid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006704///glucocorticoid biosynthetic process+++GO:0006705///mineralocorticoid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0042448///progesterone metabolic process 13081 13081 'Cyp24a1' mRNA 1 2 0 0.02 0.03 0 0.11 0.01 0.01 0.016666667 0.043333333 8 1 1 1 3.333333333 0.43420186 1.731781501 "00100///Steroid biosynthesis+++04928///Parathyroid hormone synthesis, secretion and action+++05206///MicroRNAs in cancer" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008403///25-hydroxycholecalciferol-24-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0030342///1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity+++GO:0046872///metal ion binding+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0070643///vitamin D 25-hydroxylase activity" GO:0001649///osteoblast differentiation+++GO:0010430///fatty acid omega-oxidation+++GO:0033280///response to vitamin D+++GO:0042359///vitamin D metabolic process+++GO:0042369///vitamin D catabolic process 13082 13082 'Cyp26a1' mRNA 5 3 8 0.16 0.1 0.28 0.16 0.27 0.48 0.18 0.303333333 5 8 16 5.333333333 9.666666667 0.459478828 0.835462177 00830///Retinol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0001972///retinoic acid binding+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0001822///kidney development+++GO:0006805///xenobiotic metabolic process+++GO:0007417///central nervous system development+++GO:0009952///anterior/posterior pattern specification+++GO:0014032///neural crest cell development+++GO:0016125///sterol metabolic process+++GO:0032526///response to retinoic acid+++GO:0033189///response to vitamin A+++GO:0034653///retinoic acid catabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0071300///cellular response to retinoic acid 13085 13085 'Cyp2a12' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008389///coumarin 7-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009804///coumarin metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 13087 13087 'Cyp2a5' mRNA 73 76 56 2.47 2.53 2.01 0.67 0.48 0.49 2.336666667 0.546666667 22.83 15.91 16 68.33333333 18.24666667 8.75E-07 -1.960245228 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008389///coumarin 7-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009804///coumarin metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0035634///response to stilbenoid+++GO:0042168///heme metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0071276///cellular response to cadmium ion 13090 13090 'Cyp2b19' mRNA 6 5 7 0.12 0.1 0.15 0 0 0.02 0.123333333 0.006666667 0 0 1 6 0.333333333 0.027975459 -4.084695952 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00830///Retinol metabolism+++05207///Chemical carcinogenesis - receptor activation GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process+++GO:0017144///drug metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042178///xenobiotic catabolic process+++GO:0042180///cellular ketone metabolic process+++GO:0042738///exogenous drug catabolic process 13101 13101 'Cyp2d10' mRNA 1 2 0 0.04 0.07 0 0.06 0.17 0.07 0.036666667 0.1 2 5 2 1 3 0.459816264 1.606436196 00140///Steroid hormone biosynthesis+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0042738///exogenous drug catabolic process 13105 13105 'Cyp2d9' mRNA 0 0 1 0 0 0.04 0.03 0 0 0.013333333 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 00140///Steroid hormone biosynthesis+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0042738///exogenous drug catabolic process 13106 13106 'Cyp2e1' mRNA 45 39.59 49.88 1.48 1.28 1.74 0.42 0.44 0.5 1.5 0.453333333 14.87 15.2 16.99 44.82333333 15.68666667 8.17E-04 -1.579166742 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05204///Chemical carcinogenesis - DNA adducts+++05208///Chemical carcinogenesis - reactive oxygen species GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0018601///4-nitrophenol 2-monooxygenase activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030544///Hsp70 protein binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding+++GO:0070330///aromatase activity" GO:0002933///lipid hydroxylation+++GO:0006082///organic acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process+++GO:0009617///response to bacterium+++GO:0010193///response to ozone+++GO:0010243///response to organonitrogen compound+++GO:0016098///monoterpenoid metabolic process+++GO:0017144///drug metabolic process+++GO:0018960///4-nitrophenol metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042493///response to drug+++GO:0042738///exogenous drug catabolic process+++GO:0045471///response to ethanol+++GO:0046483///heterocycle metabolic process 13107 13107 'Cyp2f2' mRNA 32 24 36 1.01 0.75 1.21 0.11 0.17 0.03 0.99 0.103333333 4 6 1 30.66666667 3.666666667 2.49E-05 -3.082467131 00980///Metabolism of xenobiotics by cytochrome P450+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009636///response to toxic substance+++GO:0018931///naphthalene metabolic process+++GO:0018979///trichloroethylene metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:1901170///naphthalene catabolic process+++GO:1901360///organic cyclic compound metabolic process 13108 13108 'Cyp2g1' mRNA 1898 1943 1965 58.83 59.35 64.61 0.46 0.52 0.39 60.93 0.456666667 17 19 14 1935.333333 16.66666667 3.86E-208 -6.872819398 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 13109 13109 'Cyp2j5' mRNA 3 0 3 0.04 0 0.05 0.01 0.03 0.03 0.03 0.023333333 1 2 2 2 1.666666667 0.90170643 -0.289791971 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0071614///linoleic acid epoxygenase activity" GO:0001990///regulation of systemic arterial blood pressure by hormone+++GO:0001998///angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0097254///renal tubular secretion+++GO:2000863///positive regulation of estrogen secretion 13110 13110 'Cyp2j6' mRNA 3792 4046 3898 56.7 59.43 61.93 32.43 31.54 30.52 59.35333333 31.49666667 2491 2362 2273 3912 2375.333333 5.85E-29 -0.73259441 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003958///NADPH-hemoprotein reductase activity+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0071614///linoleic acid epoxygenase activity" GO:0001523///retinoid metabolic process+++GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0007565///female pregnancy+++GO:0014070///response to organic cyclic compound+++GO:0019369///arachidonic acid metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 13113 13113 'Cyp3a13' mRNA 679.8 676.09 564.26 7.68 7.53 6.73 4.2 3.58 3.13 7.313333333 3.636666667 429.63 357.12 311.61 640.05 366.12 5.95E-10 -0.817110492 00140///Steroid hormone biosynthesis+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005496///steroid binding+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0050649///testosterone 6-beta-hydroxylase activity+++GO:0070330///aromatase activity+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0002933///lipid hydroxylation+++GO:0008202///steroid metabolic process+++GO:0008210///estrogen metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0042573///retinoic acid metabolic process+++GO:0070989///oxidative demethylation 13115 13115 'Cyp27b1' mRNA 24 28 30 0.24 0.28 0.32 0.15 0.29 0.28 0.28 0.24 17 33 31 27.33333333 27 0.970526463 -0.027533975 "00100///Steroid biosynthesis+++04928///Parathyroid hormone synthesis, secretion and action+++05152///Tuberculosis" GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030315///T-tubule+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004497///monooxygenase activity+++GO:0004498///calcidiol 1-monooxygenase activity+++GO:0004879///nuclear receptor activity+++GO:0005499///vitamin D binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0038186///lithocholic acid receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0070644///vitamin D response element binding+++GO:1902098///calcitriol binding+++GO:1902121///lithocholic acid binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007568///aging+++GO:0007595///lactation+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0010956///negative regulation of calcidiol 1-monooxygenase activity+++GO:0010980///positive regulation of vitamin D 24-hydroxylase activity+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030282///bone mineralization+++GO:0030308///negative regulation of cell growth+++GO:0030500///regulation of bone mineralization+++GO:0030522///intracellular receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032868///response to insulin+++GO:0033280///response to vitamin D+++GO:0034341///response to interferon-gamma+++GO:0034695///response to prostaglandin E+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0038183///bile acid signaling pathway+++GO:0042359///vitamin D metabolic process+++GO:0042368///vitamin D biosynthetic process+++GO:0042369///vitamin D catabolic process+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046688///response to copper ion+++GO:0046697///decidualization+++GO:0050892///intestinal absorption+++GO:0051591///response to cAMP+++GO:0051924///regulation of calcium ion transport+++GO:0055074///calcium ion homeostasis+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060558///regulation of calcidiol 1-monooxygenase activity+++GO:0060745///mammary gland branching involved in pregnancy+++GO:0070314///G1 to G0 transition+++GO:0070561///vitamin D receptor signaling pathway+++GO:0070564///positive regulation of vitamin D receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:1900155///negative regulation of bone trabecula formation+++GO:2000830///positive regulation of parathyroid hormone secretion" 13116 13116 'Cyp46a1' mRNA 292 331 260 6.51 7.3 6.42 2.99 3.37 2.66 6.743333333 3.006666667 154 164 135 294.3333333 151 2.54E-08 -0.970816685 00120///Primary bile acid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0033781///cholesterol 24-hydroxylase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006707///cholesterol catabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0042448///progesterone metabolic process+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1903044///protein localization to membrane raft 13120 13120 'Cyp4b1' mRNA 2 3 1 0.06 0.09 0.03 0.03 0.11 0.05 0.06 0.063333333 1 4 2 2 2.333333333 0.911197198 0.235273962 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:1901363///heterocyclic compound binding" GO:0018879///biphenyl metabolic process 13121 13121 'Cyp51' mRNA 1777 1907 1963 21.94 23.16 25.71 10.92 10.53 10.99 23.60333333 10.81333333 1018 959 992 1882.333333 989.6666667 5.56E-28 -0.941855285 00100///Steroid biosynthesis GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008398///sterol 14-demethylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" "GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0007283///spermatogenesis+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010288///response to lead ion+++GO:0016125///sterol metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0032868///response to insulin+++GO:0033488///cholesterol biosynthetic process via 24,25-dihydrolanosterol+++GO:0042177///negative regulation of protein catabolic process+++GO:0044752///response to human chorionic gonadotropin+++GO:0050709///negative regulation of protein secretion+++GO:0060282///positive regulation of oocyte development+++GO:0070988///demethylation+++GO:1900222///negative regulation of amyloid-beta clearance" 13122 13122 'Cyp7a1' mRNA 0 0 2 0 0 0.03 0 0 0 0.01 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 00120///Primary bile acid biosynthesis+++00140///Steroid hormone biosynthesis+++03320///PPAR signaling pathway+++04976///Bile secretion+++04979///Cholesterol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008123///cholesterol 7-alpha-monooxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0033782///24-hydroxycholesterol 7alpha-hydroxylase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006707///cholesterol catabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010468///regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0015721///bile acid and bile salt transport+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0038183///bile acid signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0045471///response to ethanol+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0070857///regulation of bile acid biosynthetic process+++GO:0070859///positive regulation of bile acid biosynthetic process+++GO:0071333///cellular response to glucose stimulus+++GO:0071397///cellular response to cholesterol 13123 13123 'Cyp7b1' mRNA 439 418 388 11.26 10.37 10.7 7.18 6.8 6.47 10.77666667 6.816666667 319 294 277 415 296.6666667 3.29E-04 -0.49544334 00120///Primary bile acid biosynthesis+++00140///Steroid hormone biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0008396///oxysterol 7-alpha-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0033782///24-hydroxycholesterol 7alpha-hydroxylase activity+++GO:0033783///25-hydroxycholesterol 7alpha-hydroxylase activity+++GO:0046872///metal ion binding+++GO:0047092///27-hydroxycholesterol 7-alpha-monooxygenase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0007586///digestion+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035754///B cell chemotaxis+++GO:0042632///cholesterol homeostasis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060740///prostate gland epithelium morphogenesis 13124 13124 'Cyp8b1' mRNA 2 0 0 0.06 0 0 0 0.03 0.05 0.02 0.026666667 0 1 2 0.666666667 1 0.86992923 0.606063032 00120///Primary bile acid biosynthesis+++03320///PPAR signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008397///sterol 12-alpha-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0033778///7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity+++GO:0033779///5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0031667///response to nutrient levels+++GO:0038183///bile acid signaling pathway+++GO:0045797///positive regulation of intestinal cholesterol absorption+++GO:0070723///response to cholesterol 13131 13131 'Dab1' mRNA 167 171 168 1.89 2.42 2.66 0.4 0.26 0.21 2.323333333 0.29 36 15 14 168.6666667 21.66666667 1.63E-20 -2.978625589 05017///Spinocerebellar ataxia GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005903///brush border+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0042169///SH2 domain binding+++GO:0043548///phosphatidylinositol 3-kinase binding GO:0001764///neuron migration+++GO:0007162///negative regulation of cell adhesion+++GO:0007264///small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007494///midgut development+++GO:0007628///adult walking behavior+++GO:0016358///dendrite development+++GO:0021517///ventral spinal cord development+++GO:0021589///cerebellum structural organization+++GO:0021766///hippocampus development+++GO:0021795///cerebral cortex cell migration+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021813///cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0045666///positive regulation of neuron differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0050771///negative regulation of axonogenesis+++GO:0051645///Golgi localization+++GO:0097477///lateral motor column neuron migration 13132 13132 'Dab2' mRNA 1279 1257 1454 16.03 15.66 19.21 81.26 82.56 79.13 16.96666667 80.98333333 7343 7259 6881 1330 7161 1.21E-201 2.412874552 04144///Endocytosis GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030132///clathrin coat of coated pit+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0030276///clathrin binding+++GO:0035091///phosphatidylinositol binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0038024///cargo receptor activity+++GO:0046332///SMAD binding+++GO:0050750///low-density lipoprotein particle receptor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0001701///in utero embryonic development+++GO:0001921///positive regulation of receptor recycling+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002092///positive regulation of receptor internalization+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006907///pinocytosis+++GO:0006915///apoptotic process+++GO:0007257///activation of JUN kinase activity+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0007588///excretion+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010977///negative regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0016192///vesicle-mediated transport+++GO:0030099///myeloid cell differentiation+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0032349///positive regulation of aldosterone biosynthetic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0035026///leading edge cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0045807///positive regulation of endocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0048268///clathrin coat assembly+++GO:0048545///response to steroid hormone+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071425///hematopoietic stem cell proliferation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway+++GO:2000298///regulation of Rho-dependent protein serine/threonine kinase activity+++GO:2000370///positive regulation of clathrin-dependent endocytosis+++GO:2000643///positive regulation of early endosome to late endosome transport+++GO:2000860///positive regulation of aldosterone secretion+++GO:2001046///positive regulation of integrin-mediated signaling pathway+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 13134 13134 'Dach1' mRNA 265 243 228 2.66 2.4 2.42 0.55 0.73 0.73 2.493333333 0.67 63 81 81 245.3333333 75 9.54E-17 -1.718435809 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001967///suckling behavior+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007585///respiratory gaseous exchange+++GO:0008283///cell proliferation+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0030336///negative regulation of cell migration+++GO:0033262///regulation of nuclear cell cycle DNA replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046545///development of primary female sexual characteristics+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:2000279///negative regulation of DNA biosynthetic process" 13135 13135 'Dad1' mRNA 4634 4551 4397 474.34 463.25 478.29 510.87 533.07 532.54 471.96 525.4933333 5692 5787 5735 4527.333333 5738 7.20E-09 0.330552721 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008047///enzyme activator activity GO:0001824///blastocyst development+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006915///apoptotic process+++GO:0007584///response to nutrient+++GO:0031647///regulation of protein stability+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0050790///regulation of catalytic activity 13136 13136 'Cd55' mRNA 283.4 303.06 288.97 4.16 4.31 4.64 3.8 3.63 4.08 4.37 3.836666667 265.66 233.98 287.15 291.81 262.2633333 0.362006152 -0.167335406 04610///Complement and coagulation cascades+++04640///Hematopoietic cell lineage+++05416///Viral myocarditis GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft GO:0001618///virus receptor activity+++GO:0004857///enzyme inhibitor activity+++GO:0008289///lipid binding "GO:0002376///immune system process+++GO:0002456///T cell mediated immunity+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006958///complement activation, classical pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0030449///regulation of complement activation+++GO:0030450///regulation of complement activation, classical pathway+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0045916///negative regulation of complement activation+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0046718///viral entry into host cell+++GO:1903659///regulation of complement-dependent cytotoxicity+++GO:2000516///positive regulation of CD4-positive, alpha-beta T cell activation+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation" 13137 13137 'Cd55b' mRNA 0 0 1.04 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.346666667 0 0.863090843 -0.97353728 04610///Complement and coagulation cascades+++04640///Hematopoietic cell lineage+++05416///Viral myocarditis GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0045121///membrane raft GO:0001618///virus receptor activity+++GO:0004857///enzyme inhibitor activity+++GO:0008289///lipid binding "GO:0002376///immune system process+++GO:0002456///T cell mediated immunity+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006958///complement activation, classical pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0045916///negative regulation of complement activation+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0046718///viral entry into host cell+++GO:2000516///positive regulation of CD4-positive, alpha-beta T cell activation+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation" 13138 13138 'Dag1' mRNA 5753 6109 4365 56.09 58.54 45.28 39.87 40.96 42.41 53.30333333 41.08 4693 4726 4842 5409 4753.666667 0.029727158 -0.190968532 04512///ECM-receptor interaction+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0009897///external side of plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016011///dystroglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0033268///node of Ranvier+++GO:0034399///nuclear periphery+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0070938///contractile ring+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099524///postsynaptic cytosol GO:0001618///virus receptor activity+++GO:0002162///dystroglycan binding+++GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0015631///tubulin binding+++GO:0017166///vinculin binding+++GO:0042169///SH2 domain binding+++GO:0043236///laminin binding+++GO:0043237///laminin-1 binding+++GO:0051393///alpha-actinin binding GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002009///morphogenesis of an epithelium+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007411///axon guidance+++GO:0007568///aging+++GO:0010470///regulation of gastrulation+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0014037///Schwann cell differentiation+++GO:0014044///Schwann cell development+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0016032///viral process+++GO:0016203///muscle attachment+++GO:0016340///calcium-dependent cell-matrix adhesion+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0021675///nerve development+++GO:0021682///nerve maturation+++GO:0022011///myelination in peripheral nervous system+++GO:0030336///negative regulation of cell migration+++GO:0031103///axon regeneration+++GO:0031643///positive regulation of myelination+++GO:0034453///microtubule anchoring+++GO:0043403///skeletal muscle tissue regeneration+++GO:0043409///negative regulation of MAPK cascade+++GO:0043434///response to peptide hormone+++GO:0045860///positive regulation of protein kinase activity+++GO:0046718///viral entry into host cell+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050807///regulation of synapse organization+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060055///angiogenesis involved in wound healing+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0071260///cellular response to mechanical stimulus+++GO:0071397///cellular response to cholesterol+++GO:0071679///commissural neuron axon guidance+++GO:0071711///basement membrane organization+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis 13139 13139 'Dgka' mRNA 1144 1231 1158 22.01 23.25 23.57 21.71 20.07 19.35 22.94333333 20.37666667 1324 1179 1119 1177.666667 1207.333333 0.863090843 0.023041278 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation 13143 13143 'Dapk2' mRNA 65 75 87 2.1 2.41 2.96 1.99 2.15 1.82 2.49 1.986666667 73 76 63 75.66666667 70.66666667 0.776070462 -0.115161233 04140///Autophagy - animal+++05200///Pathways in cancer+++05219///Bladder cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0034423///autophagosome lumen+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043276///anoikis+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1990266///neutrophil migration+++GO:2000424///positive regulation of eosinophil chemotaxis+++GO:2001242///regulation of intrinsic apoptotic signaling pathway 13144 13144 'Dapk3' mRNA 224 214 78 8.35 7.78 3.1 2.58 3.62 4.15 6.41 3.45 83 112 129 172 108 0.051332434 -0.660642369 04140///Autophagy - animal+++05200///Pathways in cancer+++05219///Bladder cancer "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0016605///PML body+++GO:0045121///membrane raft" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043522///leucine zipper domain binding GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007346///regulation of mitotic cell cycle+++GO:0008360///regulation of cell shape+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043519///regulation of myosin II filament organization+++GO:0046777///protein autophosphorylation+++GO:0051893///regulation of focal adhesion assembly+++GO:0071346///cellular response to interferon-gamma+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 13163 13163 'Daxx' mRNA 698 643 611 15.13 13.61 14.04 17.1 15.37 16.87 14.26 16.44666667 901 790 869 650.6666667 853.3333333 2.27E-04 0.379608159 04010///MAPK signaling pathway+++04210///Apoptosis+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05168///Herpes simplex virus 1 infection "GO:0000775///chromosome, centromeric region+++GO:0000792///heterochromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005938///cell cortex+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0043005///neuron projection+++GO:0044297///cell body" GO:0002039///p53 binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0019894///kinesin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042393///histone binding+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0050681///androgen receptor binding+++GO:0140037///sumo-dependent protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000281///mitotic cytokinesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0010832///negative regulation of myotube differentiation+++GO:0030521///androgen receptor signaling pathway+++GO:0030578///PML body organization+++GO:0031396///regulation of protein ubiquitination+++GO:0032147///activation of protein kinase activity+++GO:0033129///positive regulation of histone phosphorylation+++GO:0034605///cellular response to heat+++GO:0034620///cellular response to unfolded protein+++GO:0040014///regulation of multicellular organism growth+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071168///protein localization to chromatin+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0072738///cellular response to diamide+++GO:0097190///apoptotic signaling pathway+++GO:1901216///positive regulation of neuron death+++GO:1903936///cellular response to sodium arsenite+++GO:2001235///positive regulation of apoptotic signaling pathway" 13164 13164 'Dazl' mRNA 0 1 0 0 0.02 0 0.03 0.02 0.03 0.006666667 0.026666667 2 1 2 0.333333333 1.666666667 0.472167167 2.2018078 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005818///aster+++GO:0005819///spindle+++GO:0005844///polysome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005880///nuclear microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0032991///protein-containing complex+++GO:0043203///axon hillock+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008494///translation activator activity+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0042802///identical protein binding+++GO:0061676///importin-alpha family protein binding GO:0001556///oocyte maturation+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007020///microtubule nucleation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007147///female meiosis II+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0032147///activation of protein kinase activity+++GO:0045727///positive regulation of translation+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0045948///positive regulation of translational initiation+++GO:0048477///oogenesis+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0090307///mitotic spindle assembly 13166 13166 'Dbh' mRNA 3 11 7 0.07 0.27 0.18 0.02 0.26 0.09 0.173333333 0.123333333 1 12 4 7 5.666666667 0.852593038 -0.299421953 00350///Tyrosine metabolism GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034451///centriolar satellite+++GO:0034466///chromaffin granule lumen+++GO:0034774///secretory granule lumen+++GO:0042584///chromaffin granule membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043196///varicosity+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0045202///synapse "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0004500///dopamine beta-monooxygenase activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0016715///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding" GO:0001816///cytokine production+++GO:0001974///blood vessel remodeling+++GO:0001975///response to amphetamine+++GO:0002443///leukocyte mediated immunity+++GO:0006589///octopamine biosynthetic process+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0008542///visual learning+++GO:0042127///regulation of cell proliferation+++GO:0042309///homoiothermy+++GO:0042420///dopamine catabolic process+++GO:0042421///norepinephrine biosynthetic process+++GO:0042423///catecholamine biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0042596///fear response+++GO:0042711///maternal behavior+++GO:0045907///positive regulation of vasoconstriction+++GO:0046333///octopamine metabolic process+++GO:0048149///behavioral response to ethanol+++GO:0048265///response to pain+++GO:0050900///leukocyte migration+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 13167 13167 'Dbi' mRNA 4686.97 4518.99 4881.98 617.17 592.82 682.39 952.53 1103.62 1060.75 630.7933333 1038.966667 8248.97 9287.32 8850.99 4695.98 8795.76 7.28E-33 0.892520446 03320///PPAR signaling pathway GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0032994///protein-lipid complex+++GO:0043292///contractile fiber+++GO:0097038///perinuclear endoplasmic reticulum GO:0000062///fatty-acyl-CoA binding+++GO:0008289///lipid binding+++GO:0030156///benzodiazepine receptor binding+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042802///identical protein binding "GO:0001662///behavioral fear response+++GO:0001942///hair follicle development+++GO:0006641///triglyceride metabolic process+++GO:0007611///learning or memory+++GO:0014009///glial cell proliferation+++GO:0021670///lateral ventricle development+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0043588///skin development+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060291///long-term synaptic potentiation+++GO:1903060///negative regulation of protein lipidation+++GO:1905920///positive regulation of CoA-transferase activity+++GO:2001140///positive regulation of phospholipid transport" 13168 13168 'Dbil5' mRNA 10 2 4 1.36 0.27 0.58 0.83 0.86 0.99 0.736666667 0.893333333 7 7 8 5.333333333 7.333333333 0.740213982 0.450984254 03320///PPAR signaling pathway GO:0005737///cytoplasm GO:0000062///fatty-acyl-CoA binding+++GO:0008289///lipid binding GO:0007283///spermatogenesis 13169 13169 'Dbnl' mRNA 2486 2558 2453 58.39 59.15 61.15 59.88 57.96 58.65 59.56333333 58.83 2913 2761 2771 2499 2815 0.018667997 0.159580235 GO:0000139///Golgi membrane+++GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030427///site of polarized growth+++GO:0030665///clathrin-coated vesicle membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0051015///actin filament binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007416///synapse assembly+++GO:0016601///Rac protein signal transduction+++GO:0030833///regulation of actin filament polymerization+++GO:0045773///positive regulation of axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051017///actin filament bundle assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071800///podosome assembly+++GO:0097178///ruffle assembly+++GO:0098974///postsynaptic actin cytoskeleton organization 13170 13170 'Dbp' mRNA 2469.6 2370.99 503.13 88 83.33 21.48 9.35 15.12 17.94 64.27 14.13666667 264.59 460.8 533.3 1781.24 419.5633333 0.005595309 -2.064838723 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process" 13171 13171 'Dbt' mRNA 558 561 613 9.29 9.13 10.91 8.89 8.3 9.25 9.776666667 8.813333333 613 557 620 577.3333333 596.6666667 0.855094667 0.032501597 "00280///Valine, leucine and isoleucine degradation+++00640///Propanoate metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0042645///mitochondrial nucleoid "GO:0003863///3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0031405///lipoic acid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043754///dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity" 13175 13175 'Dclk1' mRNA 5932 6176 5536 89.19 84.86 83.59 128.6 126.82 129.23 85.88 128.2166667 11062 9895 10278 5881.333333 10411.66667 1.12E-55 0.812678483 GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0009615///response to virus+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0035556///intracellular signal transduction+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:1900181///negative regulation of protein localization to nucleus 13176 13176 'Dcc' mRNA 4 8 3 0.02 0.05 0.02 0.04 0.07 0.03 0.03 0.046666667 7 15 5 5 9 0.462103845 0.855111632 04360///Axon guidance+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032584///growth cone membrane+++GO:0044295///axonal growth cone+++GO:0045121///membrane raft+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0003713///transcription coactivator activity+++GO:0005042///netrin receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0001764///neuron migration+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0010976///positive regulation of neuron projection development+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0033563///dorsal/ventral axon guidance+++GO:0033564///anterior/posterior axon guidance+++GO:0038007///netrin-activated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0098609///cell-cell adhesion+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:1901214///regulation of neuron death" 13177 13177 'Eci1' mRNA 1412 1549 1521 81.08 87.9 92.67 69.08 70.5 66.86 87.21666667 68.81333333 1380 1373 1291 1494 1348 0.082568805 -0.161319415 00071///Fatty acid degradation GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0003824///catalytic activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016853///isomerase activity+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0042802///identical protein binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation 13178 13178 'Dck' mRNA 380 361 387 6.82 6.37 7.37 19.6 18.99 19.7 6.853333333 19.43 1257 1189 1223 376 1223 9.24E-65 1.688262482 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004136///deoxyadenosine kinase activity+++GO:0004137///deoxycytidine kinase activity+++GO:0004138///deoxyguanosine kinase activity+++GO:0005524///ATP binding+++GO:0008144///drug binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019136///deoxynucleoside kinase activity+++GO:0032546///deoxyribonucleoside binding+++GO:0032548///pyrimidine deoxyribonucleoside binding+++GO:0042803///protein homodimerization activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006170///dAMP biosynthetic process+++GO:0006220///pyrimidine nucleotide metabolic process+++GO:0009157///deoxyribonucleoside monophosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046092///deoxycytidine metabolic process+++GO:0046939///nucleotide phosphorylation 13179 13179 'Dcn' mRNA 9018 9610 9267 276.05 290.05 301.11 1316.57 1373.7 1317.65 289.07 1335.973333 49514 50433 47935 9298.333333 49294 0 2.394228075 04350///TGF-beta signaling pathway+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005589///collagen type VI trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0005539///glycosaminoglycan binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0047485///protein N-terminus binding+++GO:0050840///extracellular matrix binding GO:0001822///kidney development+++GO:0001890///placenta development+++GO:0007519///skeletal muscle tissue development+++GO:0007568///aging+++GO:0009612///response to mechanical stimulus+++GO:0010508///positive regulation of autophagy+++GO:0010596///negative regulation of endothelial cell migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016239///positive regulation of macroautophagy+++GO:0016525///negative regulation of angiogenesis+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0032496///response to lipopolysaccharide+++GO:0042060///wound healing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0090141///positive regulation of mitochondrial fission+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway 13180 13180 'Pcbd1' mRNA 119 138 124 9.78 11.23 10.81 6.31 7.44 8.25 10.60666667 7.333333333 88 101 111 127 100 0.176791463 -0.35466154 00790///Folate biosynthesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0004505///phenylalanine 4-monooxygenase activity+++GO:0005515///protein binding+++GO:0008124///4-alpha-hydroxytetrahydrobiopterin dehydratase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding "GO:0006558///L-phenylalanine metabolic process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0019293///tyrosine biosynthetic process, by oxidation of phenylalanine+++GO:0043393///regulation of protein binding+++GO:0045893///positive regulation of transcription, DNA-templated" 13184 13184 'Dcpp1' mRNA 0 2 2.4 0 0.24 0.31 0.21 0.13 0.78 0.183333333 0.373333333 2 1.16 7 1.466666667 3.386666667 0.538667886 1.30131218 GO:0005615///extracellular space GO:0003674///molecular_function GO:0001824///blastocyst development 13185 13185 'Vps26c' mRNA 1106 1304 1169 25.71 29.85 28.83 40.46 38.54 37.1 28.13 38.7 2002 1862 1777 1193 1880.333333 2.11E-14 0.644373653 GO:0005768///endosome GO:0006886///intracellular protein transport+++GO:0032456///endocytic recycling 13190 13190 'Dct' mRNA 10965 11542 11741 272.4 282.37 309.42 181.63 193.59 186.34 288.0633333 187.1866667 8408 8750 8350 11416 8502.666667 1.23E-11 -0.438331689 00350///Tyrosine metabolism+++04916///Melanogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle GO:0004167///dopachrome isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0002052///positive regulation of neuroblast proliferation+++GO:0006583///melanin biosynthetic process from tyrosine+++GO:0009637///response to blue light+++GO:0021847///ventricular zone neuroblast division+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0048468///cell development 13191 13191 'Dctn1' mRNA 3032 3096 3092 38.85 38.99 41.96 30.46 28.81 29.37 39.93333333 29.54666667 2719 2509 2531 3073.333333 2586.333333 1.44E-04 -0.26233846 04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0030286///dynein complex+++GO:0030424///axon+++GO:0030904///retromer complex+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0035371///microtubule plus-end+++GO:0036064///ciliary basal body+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle+++GO:0099738///cell cortex region+++GO:0120103///centriolar subdistal appendage GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0051010///microtubule plus-end binding "GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0007097///nuclear migration+++GO:0007528///neuromuscular junction development+++GO:0010457///centriole-centriole cohesion+++GO:0021517///ventral spinal cord development+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0032402///melanosome transport+++GO:0034454///microtubule anchoring at centrosome+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050905///neuromuscular process+++GO:0051081///nuclear envelope disassembly+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0061744///motor behavior+++GO:0070050///neuron cellular homeostasis+++GO:0090063///positive regulation of microtubule nucleation+++GO:0090316///positive regulation of intracellular protein transport+++GO:1904398///positive regulation of neuromuscular junction development+++GO:1905515///non-motile cilium assembly+++GO:1990535///neuron projection maintenance" 13194 13194 'Ddb1' mRNA 5927 6368 6297 75.95 80.26 85.55 79.75 77.45 75.79 80.58666667 77.66333333 7165 6798 6592 6197.333333 6851.666667 0.056254729 0.131201756 03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++05161///Hepatitis B+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0035861///site of double-strand break+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0044877///protein-containing complex binding+++GO:0071987///WD40-repeat domain binding+++GO:0097602///cullin family protein binding" GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010498///proteasomal protein catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0035518///histone H2A monoubiquitination+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045732///positive regulation of protein catabolic process+++GO:0046726///positive regulation by virus of viral protein levels in host cell+++GO:0048511///rhythmic process+++GO:0051702///interaction with symbiont+++GO:0070914///UV-damage excision repair+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:1902188///positive regulation of viral release from host cell 13195 13195 'Ddc' mRNA 45 49 50 1.31 1.41 1.55 0.46 0.26 0.66 1.423333333 0.46 18 10 25 48 17.66666667 0.002072451 -1.457559026 00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++04361///Axon regeneration+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism GO:0005737///cytoplasm+++GO:0008021///synaptic vesicle+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0003824///catalytic activity+++GO:0004058///aromatic-L-amino-acid decarboxylase activity+++GO:0016597///amino acid binding+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030170///pyridoxal phosphate binding+++GO:0036467///5-hydroxy-L-tryptophan decarboxylase activity+++GO:0036468///L-dopa decarboxylase activity GO:0006520///cellular amino acid metabolic process+++GO:0006584///catecholamine metabolic process+++GO:0007623///circadian rhythm+++GO:0009636///response to toxic substance+++GO:0010259///multicellular organism aging+++GO:0015842///aminergic neurotransmitter loading into synaptic vesicle+++GO:0019752///carboxylic acid metabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0035690///cellular response to drug+++GO:0042416///dopamine biosynthetic process+++GO:0042423///catecholamine biosynthetic process+++GO:0042427///serotonin biosynthetic process+++GO:0046684///response to pyrethroid+++GO:0052314///phytoalexin metabolic process+++GO:0071312///cellular response to alkaloid+++GO:0071363///cellular response to growth factor stimulus 13196 13196 'Asap1' mRNA 2113 2247 2176 18.17 18.98 19.84 14.76 13.82 14.08 18.99666667 14.22 1971 1806 1828 2178.666667 1868.333333 0.001868104 -0.234742556 04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031253///cell projection membrane+++GO:0043197///dendritic spine "GO:0001786///phosphatidylserine binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0017124///SH3 domain binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0046872///metal ion binding" GO:0030030///cell projection organization+++GO:0043547///positive regulation of GTPase activity+++GO:0060271///cilium assembly+++GO:0061000///negative regulation of dendritic spine development+++GO:0071803///positive regulation of podosome assembly+++GO:1903527///positive regulation of membrane tubulation 13197 13197 'Gadd45a' mRNA 180 230 54 9 11.35 2.86 6.18 8.22 8.92 7.736666667 7.773333333 142 184 198 154.6666667 174.6666667 0.817474966 0.192979955 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000185///activation of MAPKKK activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0016525///negative regulation of angiogenesis+++GO:0033140///negative regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042770///signal transduction in response to DNA damage+++GO:0043065///positive regulation of apoptotic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0046330///positive regulation of JNK cascade+++GO:0051726///regulation of cell cycle+++GO:0071260///cellular response to mechanical stimulus+++GO:0071479///cellular response to ionizing radiation+++GO:0071850///mitotic cell cycle arrest+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1900745///positive regulation of p38MAPK cascade+++GO:2000379///positive regulation of reactive oxygen species metabolic process 13198 13198 'Ddit3' mRNA 866 846 862 63.23 59.07 65.82 63.02 76.17 63.98 62.70666667 67.72333333 1011 1181 992 858 1061.333333 0.007032699 0.295429135 04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05202///Transcriptional misregulation in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0032993///protein-DNA complex+++GO:0036488///CHOP-C/EBP complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:1990617///CHOP-ATF4 complex+++GO:1990622///CHOP-ATF3 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008140///cAMP response element binding protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043522///leucine zipper domain binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001955///blood vessel maturation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006983///ER overload response+++GO:0006986///response to unfolded protein+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007605///sensory perception of sound+++GO:0009948///anterior/posterior axis specification+++GO:0010506///regulation of autophagy+++GO:0016055///Wnt signaling pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032713///negative regulation of interleukin-4 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042594///response to starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051726///regulation of cell cycle+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901216///positive regulation of neuron death+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:1990442///intrinsic apoptotic signaling pathway in response to nitrosative stress+++GO:2000016///negative regulation of determination of dorsal identity+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 13199 13199 'Ddn' mRNA 644 656 579 9.33 9.35 8.9 4.34 5.82 5.37 9.193333333 5.176666667 345 452 413 626.3333333 403.3333333 1.23E-06 -0.642471538 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0045944///positive regulation of transcription by RNA polymerase II 13200 13200 'Ddost' mRNA 7111 7374 7163 191.49 195.6 204.62 237.08 232.79 227.37 197.2366667 232.4133333 10123 9704 9397 7216 9741.333333 2.34E-14 0.420223276 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008047///enzyme activator activity GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0031647///regulation of protein stability+++GO:0034097///response to cytokine+++GO:0042110///T cell activation+++GO:0050790///regulation of catalytic activity 13202 13202 'Ddt' mRNA 984 934 904 122.66 115.9 119.61 107.28 120.93 116.52 119.39 114.91 982 1076 1028 940.6666667 1028.666667 0.269536884 0.118604891 GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0002020///protease binding+++GO:0005126///cytokine receptor binding+++GO:0016829///lyase activity+++GO:0033981///D-dopachrome decarboxylase activity+++GO:0050178///phenylpyruvate tautomerase activity GO:0010760///negative regulation of macrophage chemotaxis+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042438///melanin biosynthetic process+++GO:0050729///positive regulation of inflammatory response+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 13204 13204 'Dhx15' mRNA 1920 1956 1906 34.64 34.73 36.48 31.8 28.66 29.93 35.28333333 30.13 2028 1785 1848 1927.333333 1887 0.65503122 -0.043675561 03040///Spliceosome GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0071008///U2-type post-mRNA release spliceosomal complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0009636///response to toxic substance+++GO:0043279///response to alkaloid 13205 13205 'Ddx3x' mRNA 3175 3133 3236 37.25 36.15 40.27 42.67 39.78 42.4 37.89 41.61666667 4186 3813 4029 3181.333333 4009.333333 2.40E-06 0.319720141 04622///RIG-I-like receptor signaling pathway+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0043186///P granule+++GO:0061702///inflammasome complex+++GO:0072559///NLRP3 inflammasome complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003729///mRNA binding+++GO:0003924///GTPase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008143///poly(A) binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0031369///translation initiation factor binding+++GO:0033592///RNA strand annealing activity+++GO:0035613///RNA stem-loop binding+++GO:0043015///gamma-tubulin binding+++GO:0043024///ribosomal small subunit binding+++GO:0043273///CTPase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0070878///primary miRNA binding GO:0002376///immune system process+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007059///chromosome segregation+++GO:0007276///gamete generation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0009615///response to virus+++GO:0010501///RNA secondary structure unwinding+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0031053///primary miRNA processing+++GO:0031333///negative regulation of protein complex assembly+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032508///DNA duplex unwinding+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0034063///stress granule assembly+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034161///positive regulation of toll-like receptor 8 signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045948///positive regulation of translational initiation+++GO:0055088///lipid homeostasis+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071470///cellular response to osmotic stress+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0098586///cellular response to virus+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901985///positive regulation of protein acetylation+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902523///positive regulation of protein K63-linked ubiquitination+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 13206 13206 'Ddx4' mRNA 4 2 4 0.08 0.04 0.08 0.03 0.04 0.07 0.066666667 0.046666667 2 2 4 3.333333333 2.666666667 0.863090843 -0.340450197 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0071546///pi-body+++GO:0071547///piP-body+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0031047///gene silencing by RNA+++GO:0032880///regulation of protein localization+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle+++GO:1990511///piRNA biosynthetic process 13207 13207 'Ddx5' mRNA 45691.47 46068.85 47600 704.58 698.73 778.18 487.8 479.1 477.27 727.1633333 481.39 36409.68 34927.64 34493.68 46453.44 35277 5.41E-13 -0.411224813 03040///Spliceosome+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0035500///MH2 domain binding+++GO:0036002///pre-mRNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046332///SMAD binding+++GO:0048306///calcium-dependent protein binding+++GO:0050681///androgen receptor binding+++GO:0070412///R-SMAD binding+++GO:0070878///primary miRNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0001837///epithelial to mesenchymal transition+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0006606///protein import into nucleus+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0009299///mRNA transcription+++GO:0030509///BMP signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0030521///androgen receptor signaling pathway+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045069///regulation of viral genome replication+++GO:0045445///myoblast differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:2001014///regulation of skeletal muscle cell differentiation" 13209 13209 'Ddx6' mRNA 1548 1503 1526 12.04 11.62 12.61 9.84 8.98 9.51 12.09 9.443333333 1400 1251 1313 1525.666667 1321.333333 0.009429797 -0.220926609 03018///RNA degradation GO:0000792///heterochromatin+++GO:0000932///P-body+++GO:0001520///outer dense fiber+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0010494///cytoplasmic stress granule+++GO:0016442///RISC complex+++GO:0033391///chromatoid body+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0061830///concave side of sperm head+++GO:0097227///sperm annulus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding GO:0007283///spermatogenesis+++GO:0017148///negative regulation of translation+++GO:0019074///viral RNA genome packaging+++GO:0019827///stem cell population maintenance+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly+++GO:0045665///negative regulation of neuron differentiation+++GO:0048515///spermatid differentiation+++GO:1905618///positive regulation of miRNA mediated inhibition of translation 13211 13211 'Dhx9' mRNA 364 385 299 4.17 4.34 3.63 4.69 3.94 4.76 4.046666667 4.463333333 472 388 464 349.3333333 441.3333333 0.024383092 0.328330827 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005844///polysome+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016442///RISC complex+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042788///polysomal ribosome+++GO:0070578///RISC-loading complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0097165///nuclear stress granule+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001069///regulatory region RNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0031490///chromatin DNA binding+++GO:0033679///3'-5' DNA/RNA helicase activity+++GO:0034458///3'-5' RNA helicase activity+++GO:0035197///siRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0043138///3'-5' DNA helicase activity+++GO:0045142///triplex DNA binding+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061676///importin-alpha family protein binding+++GO:0070063///RNA polymerase binding+++GO:1905172///RISC complex binding+++GO:1905538///polysome binding+++GO:1990518///single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity+++GO:1990825///sequence-specific mRNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0002376///immune system process+++GO:0006353///DNA-templated transcription, termination+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0006954///inflammatory response+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0010501///RNA secondary structure unwinding+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0032508///DNA duplex unwinding+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032741///positive regulation of interleukin-18 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034605///cellular response to heat+++GO:0034622///cellular protein-containing complex assembly+++GO:0039695///DNA-templated viral transcription+++GO:0044806///G-quadruplex DNA unwinding+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045739///positive regulation of DNA repair+++GO:0045740///positive regulation of DNA replication+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048511///rhythmic process+++GO:0050434///positive regulation of viral transcription+++GO:0050684///regulation of mRNA processing+++GO:0050691///regulation of defense response to virus by host+++GO:0050729///positive regulation of inflammatory response+++GO:0051028///mRNA transport+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0070269///pyroptosis+++GO:0070922///small RNA loading onto RISC+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071360///cellular response to exogenous dsRNA+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:1904973///positive regulation of viral translation+++GO:1905698///positive regulation of polysome binding+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:2000765///regulation of cytoplasmic translation+++GO:2000767///positive regulation of cytoplasmic translation" 13244 13244 'Degs1' mRNA 3514 3723 3525 108.92 113.8 116.1 113.96 115.17 113.05 112.94 114.06 4203 4153 4049 3587.333333 4135 0.002122383 0.193142875 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0016491///oxidoreductase activity+++GO:0042284///sphingolipid delta-4 desaturase activity+++GO:0050251///retinol isomerase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043217///myelin maintenance+++GO:0046513///ceramide biosynthetic process 13340 13340 'Slc29a2' mRNA 108.39 89.82 109.6 1.81 1.37 2.07 1.04 1.1 0.98 1.75 1.04 68.64 69.91 72.93 102.6033333 70.49333333 0.049122664 -0.564854613 05034///Alcoholism GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031965///nuclear membrane+++GO:0098793///presynapse GO:0005326///neurotransmitter transporter activity+++GO:0005337///nucleoside transmembrane transporter activity+++GO:0015211///purine nucleoside transmembrane transporter activity+++GO:0015213///uridine transmembrane transporter activity GO:0001504///neurotransmitter uptake+++GO:0006836///neurotransmitter transport+++GO:0015853///adenine transport+++GO:0015854///guanine transport+++GO:0015858///nucleoside transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0015862///uridine transport+++GO:0032238///adenosine transport+++GO:0035344///hypoxanthine transport+++GO:0035364///thymine transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:0098810///neurotransmitter reuptake+++GO:1901642///nucleoside transmembrane transport 13345 13345 'Twist2' mRNA 92 87 59 4.15 3.87 2.82 6.4 8.98 9.06 3.613333333 8.146666667 163 223 223 79.33333333 203 1.54E-08 1.353493256 05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0032502///developmental process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0044092///negative regulation of molecular function+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0060325///face morphogenesis+++GO:0061303///cornea development in camera-type eye" 13346 13346 'Des' mRNA 124 122 121 2.22 2.15 2.3 2.47 2.75 2.04 2.223333333 2.42 159 173 127 122.3333333 153 0.207983056 0.311043896 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005916///fascia adherens+++GO:0005921///gap junction+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0042383///sarcolemma+++GO:0043292///contractile fiber+++GO:0045098///type III intermediate filament+++GO:0045111///intermediate filament cytoskeleton+++GO:0097512///cardiac myofibril GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0042802///identical protein binding GO:0007517///muscle organ development+++GO:0045109///intermediate filament organization 13347 13347 'Dffa' mRNA 288 260 254 9.42 8.82 9.11 9.12 7.88 8.72 9.116666667 8.573333333 318 251 269 267.3333333 279.3333333 0.824047303 0.050352453 04210///Apoptosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0044183///protein binding involved in protein folding+++GO:0060703///deoxyribonuclease inhibitor activity GO:0006309///apoptotic DNA fragmentation+++GO:0006915///apoptotic process+++GO:0032076///negative regulation of deoxyribonuclease activity+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0061077///chaperone-mediated protein folding+++GO:0070242///thymocyte apoptotic process+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:1902511///negative regulation of apoptotic DNA fragmentation 13349 13349 'Ackr1' mRNA 266.63 280.12 269.95 14.24 14.78 15.3 4.22 4.9 5.23 14.77333333 4.783333333 90.55 102.64 108.64 272.2333333 100.61 7.36E-15 -1.452824593 05144///Malaria GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0004930///G protein-coupled receptor activity+++GO:0019956///chemokine binding+++GO:0019957///C-C chemokine binding GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032642///regulation of chemokine production+++GO:0070098///chemokine-mediated signaling pathway 13350 13350 'Dgat1' mRNA 672 659 518 21.92 20.9 18.08 13.36 15.33 15.68 20.3 14.79 473 526 541 616.3333333 513.3333333 0.040830226 -0.269788641 00561///Glycerolipid metabolism+++00830///Retinol metabolism+++04975///Fat digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0004144///diacylglycerol O-acyltransferase activity+++GO:0005504///fatty acid binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019992///diacylglycerol binding+++GO:0042802///identical protein binding+++GO:0050252///retinol O-fatty-acyltransferase activity" GO:0006640///monoacylglycerol biosynthetic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0019915///lipid storage+++GO:0030073///insulin secretion+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0042572///retinol metabolic process+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0055089///fatty acid homeostasis+++GO:1901738///regulation of vitamin A metabolic process+++GO:1902224///ketone body metabolic process+++GO:1903998///regulation of eating behavior+++GO:1904729///regulation of intestinal lipid absorption+++GO:2000491///positive regulation of hepatic stellate cell activation 13353 13353 'Dgcr6' mRNA 1345 1278 1150 59.47 55.64 53.89 44.05 47.24 46.81 56.33333333 46.03333333 1144 1199 1176 1257.666667 1173 0.260332793 -0.109764312 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 13356 13356 'Dgcr2' mRNA 3791 3706 3463 50.16 48.22 48.6 40.73 39.87 38.52 48.99333333 39.70666667 3543 3388 3245 3653.333333 3392 0.072891285 -0.118291258 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0007155///cell adhesion+++GO:0009410///response to xenobiotic stimulus+++GO:0042493///response to drug+++GO:0050890///cognition 13358 13358 'Slc25a1' mRNA 2081 2117 2164 72.12 72.33 79.57 72.9 65.7 71.97 74.67333333 70.19 2417 2126 2309 2120.666667 2284 0.295492454 0.092794097 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0071913///citrate secondary active transmembrane transporter activity GO:0006843///mitochondrial citrate transmembrane transport+++GO:0055085///transmembrane transport 13360 13360 'Dhcr7' mRNA 743.11 760.08 633 16.78 17.14 15.6 14.55 14.25 13 16.50666667 13.93333333 737.02 735.2 654.09 712.0633333 708.77 0.910755912 -0.015619818 00100///Steroid biosynthesis GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0009918///sterol delta7 reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0047598///7-dehydrocholesterol reductase activity+++GO:0050661///NADP binding" GO:0001568///blood vessel development+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009791///post-embryonic development+++GO:0016126///sterol biosynthetic process+++GO:0016132///brassinosteroid biosynthetic process+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0035264///multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0045540///regulation of cholesterol biosynthetic process 13361 13361 'Dhfr' mRNA 248.68 233.53 248.5 2.51 2.31 2.66 3.08 2.69 3.12 2.493333333 2.963333333 351.7 300.07 345.8 243.57 332.5233333 0.005999645 0.43613622 00670///One carbon pool by folate+++00790///Folate biosynthesis+++01240///Biosynthesis of cofactors+++01523///Antifolate resistance GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004146///dihydrofolate reductase activity+++GO:0005542///folic acid binding+++GO:0008144///drug binding+++GO:0016491///oxidoreductase activity+++GO:0050661///NADP binding+++GO:0051870///methotrexate binding+++GO:0051871///dihydrofolic acid binding+++GO:0070402///NADPH binding+++GO:1990825///sequence-specific mRNA binding" GO:0006545///glycine biosynthetic process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0006730///one-carbon metabolic process+++GO:0017148///negative regulation of translation+++GO:0031103///axon regeneration+++GO:0031427///response to methotrexate+++GO:0035094///response to nicotine+++GO:0035999///tetrahydrofolate interconversion+++GO:0046452///dihydrofolate metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0046654///tetrahydrofolate biosynthetic process+++GO:0046655///folic acid metabolic process+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:2000121///regulation of removal of superoxide radicals 13363 13363 'Dhh' mRNA 937 1008 978 12.5 13.38 14.31 11.59 11.78 11.75 13.39666667 11.70666667 964 973 897 974.3333333 944.6666667 0.643414985 -0.05694996 04340///Hedgehog signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005113///patched binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0001708///cell fate specification+++GO:0006508///proteolysis+++GO:0007224///smoothened signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007286///spermatid development+++GO:0010468///regulation of gene expression+++GO:0016539///intein-mediated protein splicing+++GO:0016540///protein autoprocessing+++GO:0030238///male sex determination+++GO:0032355///response to estradiol+++GO:0033327///Leydig cell differentiation+++GO:0042552///myelination+++GO:0043627///response to estrogen+++GO:0050810///regulation of steroid biosynthetic process 13367 13367 'Diaph1' mRNA 625 610 512 5.85 5.61 5.08 7.62 6.77 6.59 5.513333333 6.993333333 936 813 785 582.3333333 844.6666667 1.17E-06 0.52660531 04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0072686///mitotic spindle GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007420///brain development+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0016043///cellular component organization+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0032886///regulation of microtubule-based process+++GO:0035372///protein localization to microtubule+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051493///regulation of cytoskeleton organization+++GO:0071420///cellular response to histamine 13368 13368 'Dffb' mRNA 212 190 213 5.28 4.4 5.37 4.08 3.7 2.9 5.016666667 3.56 193 168 151 205 170.6666667 0.187808033 -0.279767415 04210///Apoptosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004536///deoxyribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0097718///disordered domain specific binding GO:0006308///DNA catabolic process+++GO:0006309///apoptotic DNA fragmentation+++GO:0006915///apoptotic process+++GO:0030263///apoptotic chromosome condensation 13370 13370 'Dio1' mRNA 1 1 8 0.03 0.03 0.29 0.09 0.21 0.09 0.116666667 0.13 3 7 3 3.333333333 4.333333333 0.863090843 0.330694923 04919///Thyroid hormone signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004800///thyroxine 5'-deiodinase activity+++GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity+++GO:0033798///thyroxine 5-deiodinase activity GO:0006520///cellular amino acid metabolic process+++GO:0042403///thyroid hormone metabolic process+++GO:0042446///hormone biosynthetic process 13371 13371 'Dio2' mRNA 177 160 132 1.46 1.3 1.16 2.9 2.57 2.92 1.306666667 2.796666667 405 350 394 156.3333333 383 7.63E-16 1.2835745 04919///Thyroid hormone signaling pathway GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004800///thyroxine 5'-deiodinase activity+++GO:0016491///oxidoreductase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0033798///thyroxine 5-deiodinase activity GO:0006590///thyroid hormone generation+++GO:0009409///response to cold+++GO:0042403///thyroid hormone metabolic process+++GO:0042404///thyroid hormone catabolic process+++GO:0042446///hormone biosynthetic process+++GO:0044255///cellular lipid metabolic process+++GO:0050873///brown fat cell differentiation+++GO:0070460///thyroid-stimulating hormone secretion+++GO:0120162///positive regulation of cold-induced thermogenesis 13380 13380 'Dkk1' mRNA 4 1 2 0.1 0.02 0.05 0 0 0 0.056666667 0 0 0 0 2.333333333 0 0.187274929 -3.676610836 04310///Wnt signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0039706///co-receptor binding+++GO:0048019///receptor antagonist activity+++GO:0050750///low-density lipoprotein particle receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0001706///endoderm formation+++GO:0001707///mesoderm formation+++GO:0001942///hair follicle development+++GO:0002090///regulation of receptor internalization+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0007611///learning or memory+++GO:0010628///positive regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030279///negative regulation of ossification+++GO:0030326///embryonic limb morphogenesis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0032091///negative regulation of protein binding+++GO:0032526///response to retinoic acid+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0042663///regulation of endodermal cell fate specification+++GO:0043066///negative regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0050807///regulation of synapse organization+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060173///limb development+++GO:0060323///head morphogenesis+++GO:0060325///face morphogenesis+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0061743///motor learning+++GO:0090082///positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0090647///modulation of age-related behavioral decline+++GO:1901216///positive regulation of neuron death+++GO:1901296///negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:1904723///negative regulation of Wnt-Frizzled-LRP5/6 complex assembly+++GO:1904958///positive regulation of midbrain dopaminergic neuron differentiation+++GO:1905607///negative regulation of presynapse assembly+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000726///negative regulation of cardiac muscle cell differentiation" 13382 13382 'Dld' mRNA 1539 1573 1514 37.98 38.22 39.63 38.36 41.75 39.74 38.61 39.95 1788 1900 1793 1542 1827 0.003597419 0.233471535 "00010///Glycolysis / Gluconeogenesis+++00020///Citrate cycle (TCA cycle)+++00260///Glycine, serine and threonine metabolism+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism+++01240///Biosynthesis of cofactors" GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0043159///acrosomal matrix+++GO:0043209///myelin sheath+++GO:0045252///oxoglutarate dehydrogenase complex+++GO:0045254///pyruvate dehydrogenase complex "GO:0000166///nucleotide binding+++GO:0004148///dihydrolipoyl dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0043544///lipoamide binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding" "GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0006508///proteolysis+++GO:0007369///gastrulation+++GO:0007568///aging+++GO:0009106///lipoate metabolic process+++GO:0042391///regulation of membrane potential+++GO:0045454///cell redox homeostasis+++GO:0048240///sperm capacitation+++GO:0051068///dihydrolipoamide metabolic process+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate+++GO:0106077///histone succinylation" 13383 13383 'Dlg1' mRNA 1357.16 1393.53 1215.92 14.07 13.64 12.89 9.16 10.02 8.86 13.53333333 9.346666667 1057.26 1093.76 1025.73 1322.203333 1058.916667 1.01E-04 -0.329936379 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04660///T cell receptor signaling pathway+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis "GO:0001772///immunological synapse+++GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031253///cell projection membrane+++GO:0031594///neuromuscular junction+++GO:0033268///node of Ranvier+++GO:0033270///paranode region of axon+++GO:0035748///myelin sheath abaxonal region+++GO:0042383///sarcolemma+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043219///lateral loop+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0097060///synaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0015459///potassium channel regulator activity+++GO:0019894///kinesin binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0030165///PDZ domain binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0044325///ion channel binding+++GO:0060090///molecular adaptor activity+++GO:0097016///L27 domain binding+++GO:0098919///structural constituent of postsynaptic density GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001771///immunological synapse formation+++GO:0001935///endothelial cell proliferation+++GO:0002088///lens development in camera-type eye+++GO:0002369///T cell cytokine production+++GO:0007015///actin filament organization+++GO:0007268///chemical synaptic transmission+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009790///embryo development+++GO:0030432///peristalsis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030953///astral microtubule organization+++GO:0031503///protein-containing complex localization+++GO:0031579///membrane raft organization+++GO:0031641///regulation of myelination+++GO:0032147///activation of protein kinase activity+++GO:0032880///regulation of protein localization+++GO:0034629///cellular protein-containing complex localization+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042110///T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0042391///regulation of membrane potential+++GO:0042982///amyloid precursor protein metabolic process+++GO:0043113///receptor clustering+++GO:0043268///positive regulation of potassium ion transport+++GO:0043622///cortical microtubule organization+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0048608///reproductive structure development+++GO:0048639///positive regulation of developmental growth+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048729///tissue morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051660///establishment of centrosome localization+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060022///hard palate development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070830///bicellular tight junction assembly+++GO:0072659///protein localization to plasma membrane+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:0099562///maintenance of postsynaptic density structure+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1902473///regulation of protein localization to synapse+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903286///regulation of potassium ion import+++GO:1903753///negative regulation of p38MAPK cascade+++GO:1903760///regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:1903764///regulation of potassium ion export across plasma membrane+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 13384 13384 'Mpp3' mRNA 32 39 45 0.62 0.74 0.92 0.89 1.18 1.29 0.76 1.12 54 69 74 38.66666667 65.66666667 0.046636945 0.750024909 GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0030165///PDZ domain binding GO:0016310///phosphorylation 13385 13385 'Dlg4' mRNA 154 135 123 2.35 2 2.08 1.72 1.75 1.84 2.143333333 1.77 127 117 128 137.3333333 124 0.5619278 -0.157249886 04390///Hippo signaling pathway+++04724///Glutamatergic synapse+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030863///cortical cytoskeleton+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031594///neuromuscular junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0032839///dendrite cytoplasm+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0044224///juxtaparanode region of axon+++GO:0044300///cerebellar mossy fiber+++GO:0044306///neuron projection terminus+++GO:0044309///neuron spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0071944///cell periphery+++GO:0097060///synaptic membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099031///anchored component of postsynaptic density membrane GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019865///immunoglobulin binding+++GO:0019894///kinesin binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030165///PDZ domain binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0031748///D1 dopamine receptor binding+++GO:0031812///P2Y1 nucleotide receptor binding+++GO:0033130///acetylcholine receptor binding+++GO:0035254///glutamate receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042043///neurexin family protein binding+++GO:0044877///protein-containing complex binding+++GO:0097109///neuroligin family protein binding+++GO:0097110///scaffold protein binding+++GO:0098919///structural constituent of postsynaptic density GO:0002091///negative regulation of receptor internalization+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007626///locomotory behavior+++GO:0016188///synaptic vesicle maturation+++GO:0035176///social behavior+++GO:0035418///protein localization to synapse+++GO:0035641///locomotory exploration behavior+++GO:0035865///cellular response to potassium ion+++GO:0042220///response to cocaine+++GO:0043113///receptor clustering+++GO:0045184///establishment of protein localization+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0050806///positive regulation of synaptic transmission+++GO:0050885///neuromuscular process controlling balance+++GO:0060997///dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0065003///protein-containing complex assembly+++GO:0071625///vocalization behavior+++GO:0097061///dendritic spine organization+++GO:0097113///AMPA glutamate receptor clustering+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099562///maintenance of postsynaptic density structure+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0150012///positive regulation of neuron projection arborization+++GO:1904719///positive regulation of AMPA glutamate receptor clustering+++GO:2000310///regulation of NMDA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000821///regulation of grooming behavior 13386 13386 'Dlk1' mRNA 0 1 3 0 0.04 0.09 0.04 0.15 0.15 0.043333333 0.113333333 1 4 4 1.333333333 3 0.607260342 1.135954459 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001819///positive regulation of cytokine production+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030282///bone mineralization+++GO:0035264///multicellular organism growth+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045780///positive regulation of bone resorption+++GO:0046850///regulation of bone remodeling+++GO:0048706///embryonic skeletal system development+++GO:1905563///negative regulation of vascular endothelial cell proliferation 13388 13388 'Dll1' mRNA 891 995 817 13.8 15 13.51 2.69 2.67 2.63 14.10333333 2.663333333 200 195 191 901 195.3333333 3.87E-78 -2.214701797 01522///Endocrine resistance+++04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030957///Tat protein binding+++GO:0097110///scaffold protein binding GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001757///somite specification+++GO:0001947///heart looping+++GO:0002315///marginal zone B cell differentiation+++GO:0003323///type B pancreatic cell development+++GO:0007154///cell communication+++GO:0007219///Notch signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007386///compartment pattern specification+++GO:0007399///nervous system development+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009912///auditory receptor cell fate commitment+++GO:0009954///proximal/distal pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0014002///astrocyte development+++GO:0014807///regulation of somitogenesis+++GO:0021510///spinal cord development+++GO:0021688///cerebellar molecular layer formation+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0032693///negative regulation of interleukin-10 production+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0035265///organ growth+++GO:0040008///regulation of growth+++GO:0042472///inner ear morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0045596///negative regulation of cell differentiation+++GO:0045605///negative regulation of epidermal cell differentiation+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045807///positive regulation of endocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046331///lateral inhibition+++GO:0048630///skeletal muscle tissue growth+++GO:0048631///regulation of skeletal muscle tissue growth+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0048665///neuron fate specification+++GO:0048839///inner ear development+++GO:0050767///regulation of neurogenesis+++GO:0051302///regulation of cell division+++GO:0060041///retina development in camera-type eye+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060853///Notch signaling pathway involved in arterial endothelial cell fate commitment+++GO:0061314///Notch signaling involved in heart development+++GO:0070986///left/right axis specification+++GO:0072006///nephron development+++GO:0072014///proximal tubule development+++GO:0072070///loop of Henle development+++GO:0072583///clathrin-dependent endocytosis+++GO:0097009///energy homeostasis+++GO:0097102///endothelial tip cell fate specification+++GO:0097150///neuronal stem cell population maintenance+++GO:0098773///skin epidermis development+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:2000726///negative regulation of cardiac muscle cell differentiation 13389 13389 'Dll3' mRNA 35 30 25 0.91 0.77 0.69 0.23 0.42 0.09 0.79 0.246666667 10 18 4 30 10.66666667 0.019209543 -1.49561911 01522///Endocrine resistance+++04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001501///skeletal system development+++GO:0001701///in utero embryonic development+++GO:0001709///cell fate determination+++GO:0001756///somitogenesis+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007386///compartment pattern specification+++GO:0007399///nervous system development+++GO:0009888///tissue development+++GO:0030154///cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048339///paraxial mesoderm development+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0050768///negative regulation of neurogenesis+++GO:0050769///positive regulation of neurogenesis 13390 13390 'Dlx1' mRNA 372 365 310 6.73 6.4 6.1 1.74 2.03 1.42 6.41 1.73 117 129 90 349 112 4.93E-20 -1.648170089 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0009954///proximal/distal pattern formation+++GO:0021544///subpallium development+++GO:0021766///hippocampus development+++GO:0021879///forebrain neuron differentiation+++GO:0021892///cerebral cortex GABAergic interneuron differentiation+++GO:0021893///cerebral cortex GABAergic interneuron fate commitment+++GO:0030154///cell differentiation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0048706///embryonic skeletal system development+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:1902871///positive regulation of amacrine cell differentiation+++GO:1903845///negative regulation of cellular response to transforming growth factor beta stimulus" 13392 13392 'Dlx2' mRNA 648 546 422 14.61 12.12 10.09 5.37 5.38 5.89 12.27333333 5.546666667 274 268 291 538.6666667 277.6666667 1.59E-10 -0.961420283 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0009954///proximal/distal pattern formation+++GO:0021544///subpallium development+++GO:0021766///hippocampus development+++GO:0021772///olfactory bulb development+++GO:0021879///forebrain neuron differentiation+++GO:0021892///cerebral cortex GABAergic interneuron differentiation+++GO:0021893///cerebral cortex GABAergic interneuron fate commitment+++GO:0030154///cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045597///positive regulation of cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0048755///branching morphogenesis of a nerve+++GO:0051216///cartilage development+++GO:1902871///positive regulation of amacrine cell differentiation" 13393 13393 'Dlx3' mRNA 409 445 347 8.7 9.32 7.83 3.07 3.41 2.35 8.616666667 2.943333333 166 180 123 400.3333333 156.3333333 1.89E-15 -1.364012502 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001568///blood vessel development+++GO:0001890///placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0030154///cell differentiation+++GO:0030855///epithelial cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071895///odontoblast differentiation" 13394 13394 'Dlx4' mRNA 59 49 39 2.41 2.12 1.66 0.54 0.48 0.72 2.063333333 0.58 14 14 23 49 17 9.26E-04 -1.53259454 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0030154///cell differentiation" 13395 13395 'Dlx5' mRNA 278 301 273 11.97 12.78 12.47 7.21 7.83 7.32 12.40666667 7.453333333 195 207 188 284 196.6666667 0.001080389 -0.54064954 04550///Signaling pathways regulating pluripotency of stem cells GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001958///endochondral ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008283///cell proliferation+++GO:0009790///embryo development+++GO:0010628///positive regulation of gene expression+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0042472///inner ear morphogenesis+++GO:0043583///ear development+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060166///olfactory pit development+++GO:0060322///head development+++GO:0060325///face morphogenesis+++GO:0060349///bone morphogenesis+++GO:0071773///cellular response to BMP stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097376///interneuron axon guidance+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" 13396 13396 'Dlx6' mRNA 33 44 28 1.94 2.55 1.75 1.33 0.74 1.38 2.08 1.15 26 14 26 35 22 0.204328865 -0.678252529 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030855///epithelial cell differentiation+++GO:0042472///inner ear morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060322///head development" 13400 13400 'Dmpk' mRNA 265 242 191 5.25 4.69 4.07 6.43 6.49 6.84 4.67 6.586666667 372 364 381 232.6666667 372.3333333 1.32E-05 0.671182632 GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031965///nuclear membrane+++GO:0033017///sarcoplasmic reticulum membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017020///myosin phosphatase regulator activity+++GO:0046872///metal ion binding GO:0002028///regulation of sodium ion transport+++GO:0006468///protein phosphorylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0006998///nuclear envelope organization+++GO:0008016///regulation of heart contraction+++GO:0010657///muscle cell apoptotic process+++GO:0010830///regulation of myotube differentiation+++GO:0014722///regulation of skeletal muscle contraction by calcium ion signaling+++GO:0014853///regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051823///regulation of synapse structural plasticity 13401 13401 'Dmwd' mRNA 326 362 334 7.33 7.97 7.9 5.41 5.24 6.38 7.733333333 5.676666667 280 263 317 340.6666667 286.6666667 0.108163106 -0.260512674 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0003674///molecular_function 13404 13404 'Dmc1' mRNA 12 15 22 0.3 0.37 0.6 0.24 0.1 0.24 0.423333333 0.193333333 10 4 10 16.33333333 8 0.196005066 -1.05749447 "GO:0000781///chromosome, telomeric region+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0000150///recombinase activity+++GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0000730///DNA recombinase assembly+++GO:0001541///ovarian follicle development+++GO:0001556///oocyte maturation+++GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006312///mitotic recombination+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0007141///male meiosis I+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0042148///strand invasion+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle 13405 13405 'Dmd' mRNA 1571 1640 1594 31.76 31.64 34.08 18.85 18.13 19.04 32.49333333 18.67333333 1155 982 1009 1601.666667 1048.666667 2.03E-13 -0.624665209 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005794///Golgi apparatus+++GO:0005840///ribosome+++GO:0005856///cytoskeleton+++GO:0005883///neurofilament+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0030141///secretory granule+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0031527///filopodium membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043034///costamere+++GO:0044306///neuron projection terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097449///astrocyte projection+++GO:0099617///matrix side of mitochondrial inner membrane GO:0002162///dystroglycan binding+++GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0008270///zinc ion binding+++GO:0008307///structural constituent of muscle+++GO:0017022///myosin binding+++GO:0017166///vinculin binding+++GO:0030165///PDZ domain binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050998///nitric-oxide synthase binding+++GO:0051015///actin filament binding "GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002027///regulation of heart rate+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0007568///aging+++GO:0008065///establishment of blood-nerve barrier+++GO:0008284///positive regulation of cell proliferation+++GO:0009414///response to water deprivation+++GO:0010468///regulation of gene expression+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0010976///positive regulation of neuron projection development+++GO:0014809///regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion+++GO:0014819///regulation of skeletal muscle contraction+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0014904///myotube cell development+++GO:0021629///olfactory nerve structural organization+++GO:0021987///cerebral cortex development+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0034613///cellular protein localization+++GO:0034622///cellular protein-containing complex assembly+++GO:0035994///response to muscle stretch+++GO:0042391///regulation of membrane potential+++GO:0042692///muscle cell differentiation+++GO:0043043///peptide biosynthetic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045213///neurotransmitter receptor metabolic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0046716///muscle cell cellular homeostasis+++GO:0048666///neuron development+++GO:0048812///neuron projection morphogenesis+++GO:0051647///nucleus localization+++GO:0051726///regulation of cell cycle+++GO:0055001///muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060857///establishment of glial blood-brain barrier+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0086001///cardiac muscle cell action potential+++GO:0090257///regulation of muscle system process+++GO:0090287///regulation of cellular response to growth factor stimulus+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity" 13406 13406 'Dmp1' mRNA 428 405 371 8.43 7.88 7.85 15.58 15.36 15.14 8.053333333 15.36 907 876 847 401.3333333 876.6666667 4.07E-27 1.116769428 04512///ECM-receptor interaction GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0030544///Hsp70 protein binding+++GO:0050840///extracellular matrix binding GO:0001503///ossification+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0031214///biomineral tissue development+++GO:0070173///regulation of enamel mineralization 13409 13409 'Tmc1' mRNA 1941 1985 2089 25.59 25.72 29.19 2.16 1.95 1.97 26.83333333 2.026666667 189 166 168 2005 174.3333333 5.47E-234 -3.538613228 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032426///stereocilium tip GO:0005245///voltage-gated calcium channel activity+++GO:0005515///protein binding+++GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0007605///sensory perception of sound+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060005///vestibular reflex+++GO:0060117///auditory receptor cell development+++GO:0070588///calcium ion transmembrane transport+++GO:1903169///regulation of calcium ion transmembrane transport 13411 13411 'Dnah11' mRNA 888.65 894.18 825.99 6.62 6.26 6.56 1.87 1.45 1.86 6.48 1.726666667 300.08 251.56 287.59 869.6066667 279.7433333 2.12E-49 -1.649168361 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097728///9+0 motile cilium+++GO:0097729///9+2 motile cilium+++GO:0120134///proximal portion of axoneme "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007018///microtubule-based movement+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0007611///learning or memory+++GO:0030317///flagellated sperm motility+++GO:0035545///determination of left/right asymmetry in nervous system+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0060411///cardiac septum morphogenesis 13417 13417 'Dnah8' mRNA 185 183 185 0.64 0.62 0.67 0.11 0.06 0.09 0.643333333 0.086666667 35 18 30 184.3333333 27.66666667 3.62E-23 -2.751676643 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0036157///outer dynein arm+++GO:0042995///cell projection+++GO:0097228///sperm principal piece "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0007018///microtubule-based movement+++GO:0036158///outer dynein arm assembly 13418 13418 'Dnajc1' mRNA 988.28 1036.73 960.82 9.54 9.97 9.92 8.89 9.22 9.76 9.81 9.29 1052.64 1062.24 1113.56 995.2766667 1076.146667 0.31755143 0.102107079 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043022///ribosome binding+++GO:0051087///chaperone binding GO:0006417///regulation of translation+++GO:0006457///protein folding+++GO:0050708///regulation of protein secretion 13419 13419 'Dnase1' mRNA 836 788 779 38.15 35.73 37.77 89.42 88.86 85.94 37.21666667 88.07333333 2234 2166 2076 801 2158.666667 5.15E-75 1.418408563 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0031410///cytoplasmic vesicle GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004530///deoxyribonuclease I activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity "GO:0000737///DNA catabolic process, endonucleolytic+++GO:0002283///neutrophil activation involved in immune response+++GO:0002673///regulation of acute inflammatory response+++GO:0006308///DNA catabolic process+++GO:0006915///apoptotic process+++GO:0070948///regulation of neutrophil mediated cytotoxicity+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 13421 13421 'Dnase1l3' mRNA 15 25 29 0.22 0.36 0.45 0.79 0.56 0.64 0.343333333 0.663333333 62 43 49 23 51.33333333 0.0112096 1.136938325 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004530///deoxyribonuclease I activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity "GO:0000737///DNA catabolic process, endonucleolytic+++GO:0002283///neutrophil activation involved in immune response+++GO:0002673///regulation of acute inflammatory response+++GO:0006308///DNA catabolic process+++GO:0006309///apoptotic DNA fragmentation+++GO:0006915///apoptotic process+++GO:0010623///programmed cell death involved in cell development+++GO:0012501///programmed cell death+++GO:0070948///regulation of neutrophil mediated cytotoxicity+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 13423 13423 'Dnase2a' mRNA 255 296 316 8.46 9.76 11.27 26.98 28.21 26.38 9.83 27.19 937 957 886 289 926.6666667 7.48E-43 1.66669181 04142///Lysosome GO:0005764///lysosome GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004531///deoxyribonuclease II activity+++GO:0016787///hydrolase activity "GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006259///DNA metabolic process+++GO:0006308///DNA catabolic process+++GO:0006309///apoptotic DNA fragmentation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0030218///erythrocyte differentiation+++GO:0050776///regulation of immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 13424 13424 'Dync1h1' mRNA 2824 2763 2493 10.2 9.81 9.56 10.79 9.64 9.76 9.856666667 10.06333333 3438 3004 3013 2693.333333 3151.666667 0.002201837 0.215467348 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0002177///manchette+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0005938///cell cortex+++GO:0030175///filopodium+++GO:0030286///dynein complex+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0000278///mitotic cell cycle+++GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007097///nuclear migration+++GO:0008090///retrograde axonal transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0032388///positive regulation of intracellular transport+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly+++GO:0051293///establishment of spindle localization+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0072382///minus-end-directed vesicle transport along microtubule+++GO:0090235///regulation of metaphase plate congression+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1905832///positive regulation of spindle assembly 13426 13426 'Dync1i1' mRNA 105 110 92 2.16 2.23 2.01 0.41 0.6 0.78 2.133333333 0.596666667 23 33 43 102.3333333 33 4.90E-07 -1.638955405 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0031982///vesicle+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:1904115///axon cytoplasm+++GO:1990257///piccolo-bassoon transport vesicle" GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0030507///spectrin binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0007018///microtubule-based movement+++GO:0010970///transport along microtubule+++GO:0047496///vesicle transport along microtubule 13427 13427 'Dync1i2' mRNA 1812 2002 1958 39.55 43.12 45.53 43.99 41.52 40.59 42.73333333 42.03333333 2303 2122 2056 1924 2160.333333 0.074328695 0.153454408 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0031982///vesicle+++GO:0036157///outer dynein arm GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0007018///microtubule-based movement+++GO:0010970///transport along microtubule+++GO:0010977///negative regulation of neuron projection development 13429 13429 'Dnm1' mRNA 641 602 387 9.11 8.43 5.83 1.71 1.4 1.48 7.79 1.53 139 110 116 543.3333333 121.6666667 3.06E-33 -2.162836872 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05100///Bacterial invasion of epithelial cells GO:0001917///photoreceptor inner segment+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0043196///varicosity+++GO:0043209///myelin sheath+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0098835///presynaptic endocytic zone membrane+++GO:0098844///postsynaptic endocytic zone membrane+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0031749///D2 dopamine receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0050998///nitric-oxide synthase binding "GO:0000266///mitochondrial fission+++GO:0002031///G protein-coupled receptor internalization+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007032///endosome organization+++GO:0007605///sensory perception of sound+++GO:0008344///adult locomotory behavior+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0031623///receptor internalization+++GO:0048488///synaptic vesicle endocytosis+++GO:0050803///regulation of synapse structure or activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051932///synaptic transmission, GABAergic+++GO:0061025///membrane fusion+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1901998///toxin transport+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:1904645///response to amyloid-beta" 13430 13430 'Dnm2' mRNA 2540.05 2668.69 2635.28 39.82 41.41 44.24 48.84 48.01 47.06 41.82333333 47.97 3568.07 3432.58 3318.58 2614.673333 3439.743333 1.47E-08 0.38263128 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection "GO:0000139///Golgi membrane+++GO:0001891///phagocytic cup+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098844///postsynaptic endocytic zone membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0031749///D2 dopamine receptor binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0044877///protein-containing complex binding+++GO:0050699///WW domain binding+++GO:0050998///nitric-oxide synthase binding GO:0000266///mitochondrial fission+++GO:0002031///G protein-coupled receptor internalization+++GO:0003281///ventricular septum development+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0006893///Golgi to plasma membrane transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006909///phagocytosis+++GO:0007283///spermatogenesis+++GO:0009416///response to light stimulus+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030516///regulation of axon extension+++GO:0031623///receptor internalization+++GO:0033572///transferrin transport+++GO:0035020///regulation of Rac protein signal transduction+++GO:0035904///aorta development+++GO:0042220///response to cocaine+++GO:0044351///macropinocytosis+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045807///positive regulation of endocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048812///neuron projection morphogenesis+++GO:0050766///positive regulation of phagocytosis+++GO:0050803///regulation of synapse structure or activity+++GO:0060976///coronary vasculature development+++GO:0061025///membrane fusion+++GO:0071245///cellular response to carbon monoxide+++GO:0071481///cellular response to X-ray+++GO:0071732///cellular response to nitric oxide+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902856///negative regulation of non-motile cilium assembly+++GO:1903351///cellular response to dopamine+++GO:1903358///regulation of Golgi organization+++GO:1903408///positive regulation of sodium:potassium-exchanging ATPase activity+++GO:1903526///negative regulation of membrane tubulation+++GO:2000370///positive regulation of clathrin-dependent endocytosis 13433 13433 'Dnmt1' mRNA 1268 1297 1177 12.62 12.62 12.48 17.2 15.33 16.45 12.57333333 16.32666667 2000 1739 1851 1247.333333 1863.333333 8.10E-14 0.567416637 00270///Cysteine and methionine metabolism+++05206///MicroRNAs in cancer GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0003886///DNA (cytosine-5-)-methyltransferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0009008///DNA-methyltransferase activity+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0051718///DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0007265///Ras protein signal transduction+++GO:0008152///metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010216///maintenance of DNA methylation+++GO:0010424///DNA methylation on cytosine within a CG sequence+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016458///gene silencing+++GO:0032259///methylation+++GO:0032776///DNA methylation on cytosine+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0043045///DNA methylation involved in embryo development+++GO:0044026///DNA hypermethylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0071230///cellular response to amino acid stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090116///C-5 methylation of cytosine+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:1903926///cellular response to bisphenol A+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905460///negative regulation of vascular associated smooth muscle cell apoptotic process+++GO:1905931///negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" 13434 13434 'Trdmt1' mRNA 219.24 213.67 204.85 3.94 3.6 3.9 2.71 2.99 2.76 3.813333333 2.82 188.35 189.75 184.28 212.5866667 187.46 0.343296511 -0.192177695 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016428///tRNA (cytosine-5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001975///response to amphetamine+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0036416///tRNA stabilization 13435 13435 'Dnmt3a' mRNA 2454.56 2386.13 2274.6 9.53 9.15 8.82 8.25 8.16 8.15 9.166666667 8.186666667 2299.36 2180.28 2232.48 2371.763333 2237.373333 0.196396101 -0.095666381 00270///Cysteine and methionine metabolism+++05206///MicroRNAs in cancer "GO:0000775///chromosome, centromeric region+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix" "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003886///DNA (cytosine-5-)-methyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008168///methyltransferase activity+++GO:0009008///DNA-methyltransferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051719///DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006346///methylation-dependent chromatin silencing+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0007283///spermatogenesis+++GO:0007568///aging+++GO:0009636///response to toxic substance+++GO:0010212///response to ionizing radiation+++GO:0010216///maintenance of DNA methylation+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0030182///neuron differentiation+++GO:0031667///response to nutrient levels+++GO:0032259///methylation+++GO:0032355///response to estradiol+++GO:0032776///DNA methylation on cytosine+++GO:0033189///response to vitamin A+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043045///DNA methylation involved in embryo development+++GO:0043046///DNA methylation involved in gamete generation+++GO:0044027///hypermethylation of CpG island+++GO:0045471///response to ethanol+++GO:0071230///cellular response to amino acid stimulus+++GO:0071361///cellular response to ethanol+++GO:0071456///cellular response to hypoxia+++GO:0090116///C-5 methylation of cytosine+++GO:0097284///hepatocyte apoptotic process+++GO:1903926///cellular response to bisphenol A 13436 13436 'Dnmt3b' mRNA 77 80 79 0.98 0.99 1.07 0.87 0.75 0.91 1.013333333 0.843333333 79 64 77 78.66666667 73.33333333 0.761080407 -0.114913791 00270///Cysteine and methionine metabolism+++05206///MicroRNAs in cancer "GO:0000775///chromosome, centromeric region+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm" "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003886///DNA (cytosine-5-)-methyltransferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0009008///DNA-methyltransferase activity+++GO:0016740///transferase activity+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0051718///DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates+++GO:0051719///DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0006306///DNA methylation+++GO:0006346///methylation-dependent chromatin silencing+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0009636///response to toxic substance+++GO:0010212///response to ionizing radiation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0014823///response to activity+++GO:0031000///response to caffeine+++GO:0031503///protein-containing complex localization+++GO:0032259///methylation+++GO:0032355///response to estradiol+++GO:0033189///response to vitamin A+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043045///DNA methylation involved in embryo development+++GO:0045666///positive regulation of neuron differentiation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0060821///inactivation of X chromosome by DNA methylation+++GO:0071230///cellular response to amino acid stimulus+++GO:0071455///cellular response to hyperoxia+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090116///C-5 methylation of cytosine" 13437 13437 'Dnpep' mRNA 1100 1038 1075 37.86 35.23 39.64 48.97 51.47 51.43 37.57666667 50.62333333 1624 1665 1641 1071 1643.333333 2.39E-13 0.605299845 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006508///proteolysis 13445 13445 'Cdk2ap1' mRNA 706 605.98 528 34.42 29.17 27.31 28.07 29.48 30.96 30.3 29.50333333 661 677 704.96 613.3266667 680.9866667 0.288454041 0.143191027 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0070182///DNA polymerase binding GO:0001701///in utero embryonic development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0060325///face morphogenesis 13446 13446 'Doc2a' mRNA 0 1.73 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.576666667 0 0.863090843 -0.97353728 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098850///extrinsic component of synaptic vesicle membrane GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0016079///synaptic vesicle exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0061669///spontaneous neurotransmitter secretion 13447 13447 'Doc2b' mRNA 19 5 11 0.2 0.05 0.12 0.13 0.04 0.01 0.123333333 0.06 14 4 1 11.66666667 6.333333333 0.432234184 -0.91012239 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0046872///metal ion binding GO:0007268///chemical synaptic transmission+++GO:0008104///protein localization+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0031340///positive regulation of vesicle fusion+++GO:0032024///positive regulation of insulin secretion+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0061669///spontaneous neurotransmitter secretion 13448 13448 'Dok1' mRNA 148 164 113 5.21 5.8 4.01 14.09 15.7 16.93 5.006666667 15.57333333 478 507 552 141.6666667 512.3333333 1.54E-32 1.848949648 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0038145///macrophage colony-stimulating factor signaling pathway+++GO:0043409///negative regulation of MAPK cascade 13449 13449 'Dok2' mRNA 30 16 14 0.64 0.5 0.36 15.66 18.22 17.91 0.5 17.26333333 611 659 653 20 641 3.40E-102 4.994027743 04013///MAPK signaling pathway - fly GO:0005737///cytoplasm GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0043409///negative regulation of MAPK cascade 13476 13476 'Reep5' mRNA 6874 7053 6862 130.62 131.9 138.31 131.32 133.98 130.12 133.61 131.8066667 7951 7923 7629 6929.666667 7834.333333 0.00480346 0.164801622 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0005515///protein binding 13478 13478 'Dpagt1' mRNA 605.32 638.97 620.75 14.54 15.2 15.92 20.62 21.52 22.02 15.22 21.38666667 988.85 1008.2 1016.07 621.68 1004.373333 1.28E-12 0.681311156 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003975///UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity+++GO:0003976///UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity+++GO:0008963///phospho-N-acetylmuramoyl-pentapeptide-transferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006489///dolichyl diphosphate biosynthetic process+++GO:0019348///dolichol metabolic process 13479 13479 'Dpep1' mRNA 103 116 105 2.58 2.91 2.8 3.4 3.58 4.16 2.763333333 3.713333333 155 157 182 108 164.6666667 0.007174917 0.597944874 GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection+++GO:0045177///apical part of cell GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008800///beta-lactamase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0034235///GPI anchor binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity+++GO:0072341///modified amino acid binding GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0006691///leukotriene metabolic process+++GO:0006751///glutathione catabolic process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0016999///antibiotic metabolic process+++GO:0030336///negative regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0035690///cellular response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050667///homocysteine metabolic process+++GO:0071277///cellular response to calcium ion+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071732///cellular response to nitric oxide 13480 13480 'Dpm1' mRNA 1073 1112 1078 26.29 26.85 28.02 22.97 23.72 22.54 27.05333333 23.07666667 1078 1087 1024 1087.666667 1063 0.703304273 -0.045075652 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0033185///dolichol-phosphate-mannose synthase complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0004582///dolichyl-phosphate beta-D-mannosyltransferase activity+++GO:0005537///mannose binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0043178///alcohol binding" GO:0006486///protein glycosylation+++GO:0006506///GPI anchor biosynthetic process+++GO:0019348///dolichol metabolic process+++GO:0019673///GDP-mannose metabolic process+++GO:0035268///protein mannosylation+++GO:0035269///protein O-linked mannosylation+++GO:0097502///mannosylation 13481 13481 'Dpm2' mRNA 889 880 858 68.74 67.39 70.4 72.98 72.64 69 68.84333333 71.54 1081 1048 987 875.6666667 1038.666667 0.013460641 0.234204017 00510///N-Glycan biosynthesis+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033185///dolichol-phosphate-mannose synthase complex+++GO:0048471///perinuclear region of cytoplasm GO:0004582///dolichyl-phosphate beta-D-mannosyltransferase activity+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0030234///enzyme regulator activity GO:0006486///protein glycosylation+++GO:0006506///GPI anchor biosynthetic process+++GO:0019348///dolichol metabolic process+++GO:0031647///regulation of protein stability+++GO:0050790///regulation of catalytic activity+++GO:0097502///mannosylation 13482 13482 'Dpp4' mRNA 819.99 933 974 10.13 11.33 13.38 19.89 17.32 17.31 11.61333333 18.17333333 1827 1613 1523 908.9966667 1654.333333 5.05E-17 0.848466781 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0046581///intercellular canaliculus GO:0001618///virus receptor activity+++GO:0002020///protease binding+++GO:0004177///aminopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045499///chemorepellent activity GO:0001662///behavioral fear response+++GO:0001666///response to hypoxia+++GO:0002337///B-1a B cell differentiation+++GO:0002709///regulation of T cell mediated immunity+++GO:0002717///positive regulation of natural killer cell mediated immunity+++GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0008284///positive regulation of cell proliferation+++GO:0010716///negative regulation of extracellular matrix disassembly+++GO:0031295///T cell costimulation+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0035641///locomotory exploration behavior+++GO:0036343///psychomotor behavior+++GO:0042110///T cell activation+++GO:0043542///endothelial cell migration+++GO:0046718///viral entry into host cell+++GO:0050919///negative chemotaxis+++GO:0051234///establishment of localization+++GO:0090024///negative regulation of neutrophil chemotaxis 13483 13483 'Dpp6' mRNA 23 13 13 0.27 0.15 0.16 0.01 0.01 0 0.193333333 0.006666667 1 1 0 16.33333333 0.666666667 6.19E-04 -4.622918904 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0015459///potassium channel regulator activity GO:0006508///proteolysis+++GO:0019228///neuronal action potential+++GO:0042391///regulation of membrane potential+++GO:0043266///regulation of potassium ion transport+++GO:0043268///positive regulation of potassium ion transport+++GO:0072659///protein localization to plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903078///positive regulation of protein localization to plasma membrane 13486 13486 'Dr1' mRNA 550 608 613 9.79 10.65 11.58 15.89 15.3 16.19 10.67333333 15.79333333 1027 966 1013 590.3333333 1002 1.37E-13 0.749643876 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0017054///negative cofactor 2 complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0001046///core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0046982///protein heterodimerization activity+++GO:0140223///general transcription initiation factor activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006338///chromatin remodeling+++GO:0006351///transcription, DNA-templated+++GO:0043966///histone H3 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly" 13488 13488 'Drd1' mRNA 0 3 1 0 0.05 0.02 0.04 0.01 0.08 0.023333333 0.043333333 3 1 6 1.333333333 3.333333333 0.533067624 1.319304733 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04540///Gap junction+++04728///Dopaminergic synapse+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043679///axon terminus+++GO:0044326///dendritic spine neck+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0001588///dopamine neurotransmitter receptor activity, coupled via Gs+++GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004952///dopamine neurotransmitter receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0031701///angiotensin receptor binding+++GO:0031750///D3 dopamine receptor binding+++GO:0035240///dopamine binding+++GO:0044877///protein-containing complex binding+++GO:0051117///ATPase binding+++GO:1901363///heterocyclic compound binding" "GO:0001659///temperature homeostasis+++GO:0001661///conditioned taste aversion+++GO:0001662///behavioral fear response+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001963///synaptic transmission, dopaminergic+++GO:0001964///startle response+++GO:0001975///response to amphetamine+++GO:0006469///negative regulation of protein kinase activity+++GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007612///learning+++GO:0007613///memory+++GO:0007617///mating behavior+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0007631///feeding behavior+++GO:0008306///associative learning+++GO:0008542///visual learning+++GO:0009410///response to xenobiotic stimulus+++GO:0010628///positive regulation of gene expression+++GO:0014002///astrocyte development+++GO:0015872///dopamine transport+++GO:0019226///transmission of nerve impulse+++GO:0019228///neuronal action potential+++GO:0019229///regulation of vasoconstriction+++GO:0019722///calcium-mediated signaling+++GO:0021542///dentate gyrus development+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0030432///peristalsis+++GO:0035106///operant conditioning+++GO:0035176///social behavior+++GO:0042053///regulation of dopamine metabolic process+++GO:0042220///response to cocaine+++GO:0042311///vasodilation+++GO:0042321///negative regulation of circadian sleep/wake cycle, sleep+++GO:0042493///response to drug+++GO:0042711///maternal behavior+++GO:0042755///eating behavior+++GO:0043269///regulation of ion transport+++GO:0043987///histone H3-S10 phosphorylation+++GO:0045838///positive regulation of membrane potential+++GO:0046323///glucose import+++GO:0046959///habituation+++GO:0046960///sensitization+++GO:0048148///behavioral response to cocaine+++GO:0050805///negative regulation of synaptic transmission+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060134///prepulse inhibition+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0060548///negative regulation of cell death+++GO:0071870///cellular response to catecholamine stimulus+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0099010///modification of postsynaptic structure+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903351///cellular response to dopamine+++GO:2000253///positive regulation of feeding behavior+++GO:2000300///regulation of synaptic vesicle exocytosis" 13490 13490 'Drd3' mRNA 1 0 0 0.04 0 0 0 0.04 0 0.013333333 0.013333333 0 2 0 0.333333333 0.666666667 0.863090843 0.906675773 04080///Neuroactive ligand-receptor interaction+++04728///Dopaminergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0098691///dopaminergic synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane "GO:0001591///dopamine neurotransmitter receptor activity, coupled via Gi/Go+++GO:0004930///G protein-coupled receptor activity+++GO:0004952///dopamine neurotransmitter receptor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0031748///D1 dopamine receptor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001963///synaptic transmission, dopaminergic+++GO:0001975///response to amphetamine+++GO:0002016///regulation of blood volume by renin-angiotensin+++GO:0002031///G protein-coupled receptor internalization+++GO:0006874///cellular calcium ion homeostasis+++GO:0006914///autophagy+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007195///adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0007626///locomotory behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0009410///response to xenobiotic stimulus+++GO:0014059///regulation of dopamine secretion+++GO:0019216///regulation of lipid metabolic process+++GO:0032416///negative regulation of sodium:proton antiporter activity+++GO:0032467///positive regulation of cytokinesis+++GO:0032922///circadian regulation of gene expression+++GO:0034776///response to histamine+++GO:0035483///gastric emptying+++GO:0035815///positive regulation of renal sodium excretion+++GO:0040012///regulation of locomotion+++GO:0040014///regulation of multicellular organism growth+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043266///regulation of potassium ion transport+++GO:0043278///response to morphine+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0045471///response to ethanol+++GO:0045776///negative regulation of blood pressure+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046717///acid secretion+++GO:0048148///behavioral response to cocaine+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0050482///arachidonic acid secretion+++GO:0050709///negative regulation of protein secretion+++GO:0050883///musculoskeletal movement, spinal reflex action+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051580///regulation of neurotransmitter uptake+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0060134///prepulse inhibition+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0060160///negative regulation of dopamine receptor signaling pathway+++GO:0060161///positive regulation of dopamine receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0090325///regulation of locomotion involved in locomotory behavior+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1901386///negative regulation of voltage-gated calcium channel activity" 13491 13491 'Drd4' mRNA 7 10 6 0.2 0.25 0.13 0 0.05 0.05 0.193333333 0.033333333 0 3 1 7.666666667 1.333333333 0.075836599 -2.516845779 04080///Neuroactive ligand-receptor interaction+++04728///Dopaminergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0001591///dopamine neurotransmitter receptor activity, coupled via Gi/Go+++GO:0004930///G protein-coupled receptor activity+++GO:0004952///dopamine neurotransmitter receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0017124///SH3 domain binding+++GO:0030594///neurotransmitter receptor activity+++GO:0035240///dopamine binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051379///epinephrine binding+++GO:0051380///norepinephrine binding+++GO:1901363///heterocyclic compound binding" "GO:0000187///activation of MAPK activity+++GO:0001662///behavioral fear response+++GO:0001963///synaptic transmission, dopaminergic+++GO:0001975///response to amphetamine+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007195///adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007614///short-term memory+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0008355///olfactory learning+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0033674///positive regulation of kinase activity+++GO:0034776///response to histamine+++GO:0042053///regulation of dopamine metabolic process+++GO:0042596///fear response+++GO:0042752///regulation of circadian rhythm+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048148///behavioral response to cocaine+++GO:0048511///rhythmic process+++GO:0050482///arachidonic acid secretion+++GO:0050709///negative regulation of protein secretion+++GO:0050805///negative regulation of synaptic transmission+++GO:0050848///regulation of calcium-mediated signaling+++GO:0060080///inhibitory postsynaptic potential+++GO:0060406///positive regulation of penile erection+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential" 13492 13492 'Drd5' mRNA 0 0 1 0 0 0.02 0.02 0 0 0.006666667 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04728///Dopaminergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031526///brush border membrane+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane "GO:0001588///dopamine neurotransmitter receptor activity, coupled via Gs+++GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004952///dopamine neurotransmitter receptor activity+++GO:0035240///dopamine binding" "GO:0001963///synaptic transmission, dopaminergic+++GO:0001975///response to amphetamine+++GO:0001992///regulation of systemic arterial blood pressure by vasopressin+++GO:0001994///norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0006469///negative regulation of protein kinase activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007617///mating behavior+++GO:0008306///associative learning+++GO:0008542///visual learning+++GO:0019226///transmission of nerve impulse+++GO:0030336///negative regulation of cell migration+++GO:0033861///negative regulation of NAD(P)H oxidase activity+++GO:0042060///wound healing+++GO:0042220///response to cocaine+++GO:0045776///negative regulation of blood pressure+++GO:0045924///regulation of female receptivity+++GO:0046960///sensitization+++GO:0060292///long-term synaptic depression+++GO:0071870///cellular response to catecholamine stimulus+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0072593///reactive oxygen species metabolic process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels" 13494 13494 'Drg1' mRNA 1853.74 1941.91 1934.39 64.35 66.66 72.04 74.08 77.79 70.56 67.68333333 74.14333333 2377.19 2444.23 2209.39 1910.013333 2343.603333 3.86E-04 0.28281179 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0002181///cytoplasmic translation+++GO:0031116///positive regulation of microtubule polymerization+++GO:1901673///regulation of mitotic spindle assembly 13495 13495 'Drg2' mRNA 1352 1411 1376 43.62 44.87 47.1 44.13 44.69 40.87 45.19666667 43.23 1572 1554 1409 1379.666667 1511.666667 0.203494936 0.119336867 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002181///cytoplasmic translation 13496 13496 'Arid3a' mRNA 78 67 83 0.78 0.66 0.87 1.31 1.2 1.78 0.77 1.43 151 136 198 76 161.6666667 2.17E-05 1.073776978 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045121///membrane raft GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 13497 13497 'Drp2' mRNA 2376 2453 2268 18.55 18.74 18.67 8.4 7.6 7.76 18.65333333 7.92 1255 1108 1116 2365.666667 1159.666667 1.06E-46 -1.040574191 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0007417///central nervous system development+++GO:0050808///synapse organization+++GO:0099536///synaptic signaling 13498 13498 'Atn1' mRNA 1832 1840 1458 22.39 22.12 18.9 14.59 13.29 14.34 21.13666667 14.07333333 1374 1223 1308 1710 1301.666667 3.60E-06 -0.401776996 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0019904///protein domain specific binding+++GO:0090729///toxin activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0008340///determination of adult lifespan+++GO:0008584///male gonad development+++GO:0009404///toxin metabolic process+++GO:0009791///post-embryonic development+++GO:0016477///cell migration+++GO:0030011///maintenance of cell polarity+++GO:0032094///response to food+++GO:0035264///multicellular organism growth+++GO:0035821///modification of morphology or physiology of other organism+++GO:0045664///regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051402///neuron apoptotic process" 13506 13506 'Dsc2' mRNA 67 65 60 0.78 0.74 0.74 1.05 0.53 0.93 0.753333333 0.836666667 104 51 89 64 81.33333333 0.383491881 0.330295325 05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0031410///cytoplasmic vesicle GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009267///cellular response to starvation+++GO:0086042///cardiac muscle cell-cardiac muscle cell adhesion+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential 13508 13508 'Dscam' mRNA 54 69 59 0.37 0.5 0.38 0.06 0.05 0.03 0.416666667 0.046666667 11 7 5 60.66666667 7.666666667 1.39E-09 -2.997869727 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0005515///protein binding+++GO:0098632///cell-cell adhesion mediator activity+++GO:1990782///protein tyrosine kinase binding+++GO:1990890///netrin receptor binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007416///synapse assembly+++GO:0007626///locomotory behavior+++GO:0010842///retina layer formation+++GO:0038007///netrin-activated signaling pathway+++GO:0042327///positive regulation of phosphorylation+++GO:0048813///dendrite morphogenesis+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0060060///post-embryonic retina morphogenesis in camera-type eye+++GO:0060219///camera-type eye photoreceptor cell differentiation+++GO:0070593///dendrite self-avoidance 13511 13511 'Dsg2' mRNA 211 215 189 1.94 1.95 1.85 1.57 1.77 1.72 1.913333333 1.686666667 196 216 208 205 206.6666667 0.998041261 0.002677328 05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0043231///intracellular membrane-bounded organelle GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding GO:0002934///desmosome organization+++GO:0003165///Purkinje myocyte development+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0032570///response to progesterone+++GO:0060135///maternal process involved in female pregnancy+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential 13516 13516 'Epyc' mRNA 11 14 14 0.37 0.46 0.5 0.94 0.72 0.88 0.443333333 0.846666667 34 28 30 13 30.66666667 0.027485912 1.223201753 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0007605///sensory perception of sound+++GO:0060348///bone development+++GO:0061975///articular cartilage development 13518 13518 'Dst' mRNA 3229.98 3193.68 2757.67 8.9 8.64 8.12 5.3 4.77 4.76 8.553333333 4.943333333 2244.03 1979.38 1923 3060.443333 2048.803333 2.31E-16 -0.588929284 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0030424///axon+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0031673///H zone+++GO:0035371///microtubule plus-end+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0045098///type III intermediate filament+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0060053///neurofilament cytoskeleton+++GO:0097038///perinuclear endoplasmic reticulum+++GO:1904115///axon cytoplasm GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005198///structural molecule activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051010///microtubule plus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0007409///axonogenesis+++GO:0008090///retrograde axonal transport+++GO:0009611///response to wounding+++GO:0030011///maintenance of cell polarity+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031581///hemidesmosome assembly+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0046907///intracellular transport+++GO:0048870///cell motility 13521 13521 'Slc26a2' mRNA 615 731 572 8.61 10.07 8.49 12.39 11.29 11.57 9.056666667 11.75 1019 907 921 639.3333333 949 7.50E-08 0.560377814 05208///Chemical carcinogenesis - reactive oxygen species GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity GO:0001503///ossification+++GO:0006811///ion transport+++GO:0008272///sulfate transport+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0055085///transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 13522 13522 'Adam28' mRNA 50.44 33.81 40.57 0.68 0.44 0.58 0.19 0.11 0.12 0.566666667 0.14 16.29 9.61 9.74 41.60666667 11.88 3.76E-04 -1.872032769 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway 13524 13524 'Adam18' mRNA 0 1 1 0 0.02 0.03 0 0.04 0 0.016666667 0.013333333 0 2 0 0.666666667 0.666666667 0.999469949 -0.00317094 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0005178///integrin binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007339///binding of sperm to zona pellucida+++GO:0030154///cell differentiation 13527 13527 'Dtna' mRNA 3806 3794 3564 44.98 43.49 43.92 17.25 17.07 18.77 44.13 17.69666667 1616 1415 1554 3721.333333 1528.333333 1.66E-87 -1.295882413 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016014///dystrobrevin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0045111///intermediate filament cytoskeleton+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding GO:0099536///synaptic signaling 13528 13528 'Dtnb' mRNA 1315 1317 804 17.33 16.9 10.68 7.9 8.84 8.96 14.97 8.566666667 700 743 755 1145.333333 732.6666667 3.06E-06 -0.645087757 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0060077///inhibitory synapse+++GO:0098794///postsynapse GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019902///phosphatase binding+++GO:0046872///metal ion binding GO:0030182///neuron differentiation+++GO:0099536///synaptic signaling 13531 13531 'Usp17la' mRNA 6 6 6.1 0.13 0.12 0.14 0.02 0 0.17 0.13 0.063333333 1 0 9 6.033333333 3.333333333 0.601854074 -0.857904056 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0042981///regulation of apoptotic process 13537 13537 'Dusp2' mRNA 14 7 10 0.51 0.25 0.38 2.48 2.48 3.02 0.38 2.66 79 77 93 10.33333333 83 1.80E-12 2.994110955 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0001706///endoderm formation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade 13542 13542 'Dvl1' mRNA 387 392 325 6.28 6.25 5.62 6.59 4.99 5.53 6.05 5.703333333 463 344 380 368 395.6666667 0.612611598 0.093517818 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:1990909///Wnt signalosome GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding "GO:0001505///regulation of neurotransmitter levels+++GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0007269///neurotransmitter secretion+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007528///neuromuscular junction development+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0021915///neural tube development+++GO:0022007///convergent extension involved in neural plate elongation+++GO:0031122///cytoplasmic microtubule organization+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0035176///social behavior+++GO:0035372///protein localization to microtubule+++GO:0035556///intracellular signal transduction+++GO:0043113///receptor clustering+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048668///collateral sprouting+++GO:0048675///axon extension+++GO:0048813///dendrite morphogenesis+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0060029///convergent extension involved in organogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060134///prepulse inhibition+++GO:0060997///dendritic spine morphogenesis+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0099054///presynapse assembly+++GO:0099173///postsynapse organization+++GO:0150012///positive regulation of neuron projection arborization+++GO:1903827///regulation of cellular protein localization+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential" 13543 13543 'Dvl2' mRNA 722 701 506 13.37 12.77 9.94 10.07 9.14 8.36 12.02666667 9.19 626 555 503 643 561.3333333 0.169432527 -0.202393234 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0016328///lateral plasma membrane+++GO:0016604///nuclear body+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0045177///apical part of cell "GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association" "GO:0001843///neural tube closure+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003007///heart morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007379///segment specification+++GO:0007507///heart development+++GO:0016055///Wnt signaling pathway+++GO:0022007///convergent extension involved in neural plate elongation+++GO:0034613///cellular protein localization+++GO:0035282///segmentation+++GO:0035556///intracellular signal transduction+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0044340///canonical Wnt signaling pathway involved in regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060029///convergent extension involved in organogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0150012///positive regulation of neuron projection arborization" 13544 13544 'Dvl3' mRNA 1565.57 1389.61 1395.32 17.34 15.13 16.42 14.13 12.58 13.3 16.29666667 13.33666667 1474 1279.61 1343 1450.166667 1365.536667 0.323802795 -0.099235982 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000785///chromatin+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:1990909///Wnt signalosome "GO:0002020///protease binding+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding" "GO:0001934///positive regulation of protein phosphorylation+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0032880///regulation of protein localization+++GO:0035556///intracellular signal transduction+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042493///response to drug+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0150012///positive regulation of neuron projection arborization+++GO:1903827///regulation of cellular protein localization+++GO:1904948///midbrain dopaminergic neuron differentiation" 13548 13548 'Dyrk1a' mRNA 707 712 736 6.92 6.82 7.56 5.58 5.12 5.47 7.1 5.39 660 589 623 718.3333333 624 0.058736888 -0.217165651 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005883///neurofilament+++GO:0005884///actin filament+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0015631///tubulin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0048156///tau protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006468///protein phosphorylation+++GO:0007623///circadian rhythm+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0031115///negative regulation of microtubule polymerization+++GO:0033120///positive regulation of RNA splicing+++GO:0034205///amyloid-beta formation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0090312///positive regulation of protein deacetylation" 13549 13549 'Dyrk1b' mRNA 2135.63 1964 1621.11 16.76 15.4 12.82 5.96 7.21 7.41 14.99333333 6.86 731 718.33 765 1906.913333 738.11 6.04E-51 -1.376687831 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006468///protein phosphorylation+++GO:0007520///myoblast fusion+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060612///adipose tissue development" 13555 13555 'E2f1' mRNA 10 11 13 0.2 0.22 0.28 3.73 3.53 4.37 0.233333333 3.876666667 209.04 193.29 237.19 11.33333333 213.1733333 1.74E-37 4.219504611 01522///Endocrine resistance+++04110///Cell cycle+++04137///Mitophagy - animal+++04218///Cellular senescence+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0032991///protein-containing complex+++GO:0035189///Rb-E2F complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000077///DNA damage checkpoint+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010628///positive regulation of gene expression+++GO:0030900///forebrain development+++GO:0043065///positive regulation of apoptotic process+++GO:0043276///anoikis+++GO:0043392///negative regulation of DNA binding+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048255///mRNA stabilization+++GO:0051726///regulation of cell cycle+++GO:0060252///positive regulation of glial cell proliferation+++GO:0070345///negative regulation of fat cell proliferation+++GO:0071398///cellular response to fatty acid+++GO:0071456///cellular response to hypoxia+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071930///negative regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1990086///lens fiber cell apoptotic process+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 13557 13557 'E2f3' mRNA 581.16 585.64 438.31 2.63 2.65 1.92 2.02 1.49 1.67 2.4 1.726666667 498.69 329.37 413.19 535.0366667 413.75 0.016872926 -0.380828336 01522///Endocrine resistance+++04110///Cell cycle+++04218///Cellular senescence+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070345///negative regulation of fat cell proliferation+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process" 13559 13559 'E2f5' mRNA 731 700 566 23.56 22.41 19.48 13.27 15.75 16.6 21.81666667 15.20666667 469 543 560 665.6666667 524 0.00671551 -0.351192756 04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016528///sarcoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009887///animal organ morphogenesis+++GO:0030030///cell projection organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle" 13560 13560 'E4f1' mRNA 717 749 771 15.12 15.53 17.34 13.74 13.03 11.84 15.99666667 12.87 753 697 630 745.6666667 693.3333333 0.358594815 -0.119339677 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0035497///cAMP response element binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0009790///embryo development+++GO:0009794///regulation of mitotic cell cycle, embryonic+++GO:0010564///regulation of cell cycle process+++GO:0016567///protein ubiquitination+++GO:0040008///regulation of growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division" 13587 13587 'Ear2' mRNA 3.01 1 2 0.3 0.1 0.21 3.96 2.89 3.41 0.203333333 3.42 45.77 32.44 37.99 2.003333333 38.73333333 9.44E-08 4.233003437 GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0002227///innate immune response in mucosa+++GO:0006935///chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 13589 13589 'Mapre1' mRNA 3473.67 3723.12 3494.22 45.22 44.15 46.02 53.73 56.74 55.7 45.13 55.39 5001.35 4996.8 4963.66 3563.67 4987.27 1.25E-15 0.473294994 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005925///focal adhesion+++GO:0015630///microtubule cytoskeleton+++GO:0030981///cortical microtubule cytoskeleton+++GO:0031253///cell projection membrane+++GO:0035371///microtubule plus-end+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0051233///spindle midzone+++GO:1905721///mitotic spindle astral microtubule end GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0051010///microtubule plus-end binding GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0016477///cell migration+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0035372///protein localization to microtubule+++GO:0046785///microtubule polymerization+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0071539///protein localization to centrosome+++GO:1903033///positive regulation of microtubule plus-end binding+++GO:1904825///protein localization to microtubule plus-end+++GO:1905515///non-motile cilium assembly 13590 13590 'Lefty1' mRNA 70 39 47 2.52 1.39 1.8 2.76 2.35 3.05 1.903333333 2.72 88 73 94.15 52 85.05 0.041867314 0.696954414 04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity+++GO:0038100///nodal binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003007///heart morphogenesis+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0008285///negative regulation of cell proliferation+++GO:0009948///anterior/posterior axis specification+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0032526///response to retinoic acid+++GO:0042074///cell migration involved in gastrulation+++GO:0060395///SMAD protein signal transduction+++GO:1900108///negative regulation of nodal signaling pathway+++GO:1900124///negative regulation of nodal receptor complex assembly 13591 13591 'Ebf1' mRNA 3112 3213 2759 26.94 28.18 26.53 18.25 15.49 18.73 27.21666667 17.49 2328 1953 2338 3028 2206.333333 8.30E-10 -0.467154948 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0070742///C2H2 zinc finger domain binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 13592 13592 'Ebf2' mRNA 64 58 48 0.68 0.6 0.54 0.31 0.51 0.45 0.606666667 0.423333333 34 54 47 56.66666667 45 0.42873607 -0.336819492 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity" "GO:0001709///cell fate determination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0035563///positive regulation of chromatin binding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050873///brown fat cell differentiation+++GO:0060612///adipose tissue development+++GO:0120162///positive regulation of cold-induced thermogenesis" 13593 13593 'Ebf3' mRNA 110 106 130 1.2 1.2 1.5 0.61 0.47 0.49 1.3 0.523333333 58 48 50 115.3333333 52 3.45E-05 -1.167332103 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 13595 13595 'Ebp' mRNA 769 754 757 25.53 24.67 26.66 33.8 37.26 33.05 25.62 34.70333333 1170 1259 1107 760 1178.666667 9.37E-11 0.621351043 00100///Steroid biosynthesis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0000247///C-8 sterol isomerase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0047750///cholestenol delta-isomerase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016125///sterol metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0030097///hemopoiesis 13599 13599 'Ecel1' mRNA 2 8 6 0.04 0.15 0.12 0.99 0.94 0.77 0.103333333 0.9 59 55 45 5.333333333 53 6.52E-09 3.300109489 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0003016///respiratory system process+++GO:0006508///proteolysis+++GO:0007218///neuropeptide signaling pathway+++GO:0016485///protein processing+++GO:0035556///intracellular signal transduction 13601 13601 'Ecm1' mRNA 124 97 104 3.71 2.88 3.32 73.63 78.58 74.84 3.303333333 75.68333333 2805 2915 2752 108.3333333 2824 0 4.693579731 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005134///interleukin-2 receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0043236///laminin binding GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0002063///chondrocyte development+++GO:0002828///regulation of type 2 immune response+++GO:0003416///endochondral bone growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0010466///negative regulation of peptidase activity+++GO:0030500///regulation of bone mineralization+++GO:0030502///negative regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0045766///positive regulation of angiogenesis+++GO:2000404///regulation of T cell migration 13602 13602 'Sparcl1' mRNA 29649 31089 30863 521.79 537.91 575.42 283.5 275.01 280.45 545.04 279.6533333 18533 17586 17776 30533.66667 17965 1.02E-47 -0.778708431 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0098965///extracellular matrix of synaptic cleft+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding+++GO:0070052///collagen V binding GO:0007165///signal transduction+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0048856///anatomical structure development+++GO:0050807///regulation of synapse organization+++GO:0099560///synaptic membrane adhesion 13603 13603 'Opn3' mRNA 84 77 55 3.1 2.48 2.27 3.15 4.84 4.48 2.616666667 4.156666667 96 147 139 72 127.3333333 0.004260709 0.820975276 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005502///11-cis retinal binding+++GO:0005503///all-trans retinal binding+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007602///phototransduction+++GO:0009584///detection of visible light+++GO:0009637///response to blue light+++GO:0018298///protein-chromophore linkage+++GO:0030216///keratinocyte differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0046326///positive regulation of glucose import+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0050896///response to stimulus+++GO:0071482///cellular response to light stimulus+++GO:0071492///cellular response to UV-A+++GO:1901857///positive regulation of cellular respiration 13605 13605 'Ect2' mRNA 197 200 175 2.64 2.61 2.46 3.17 3.46 3.09 2.57 3.24 274 291 256 190.6666667 273.6666667 0.002597675 0.512001433 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0072686///mitotic spindle+++GO:0097149///centralspindlin complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity "GO:0000281///mitotic cytokinesis+++GO:0000902///cell morphogenesis+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0032147///activation of protein kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0035556///intracellular signal transduction+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0045859///regulation of protein kinase activity+++GO:0051260///protein homooligomerization+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070830///bicellular tight junction assembly+++GO:0071277///cellular response to calcium ion+++GO:0071479///cellular response to ionizing radiation+++GO:0090630///activation of GTPase activity+++GO:2000431///regulation of cytokinesis, actomyosin contractile ring assembly" 13607 13607 'Eda' mRNA 48 83 69 0.52 0.88 0.8 0.21 0.17 0.23 0.733333333 0.203333333 22 18 24 66.66666667 21.33333333 4.43E-05 -1.656828329 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell GO:0005102///signaling receptor binding+++GO:0005123///death receptor binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0038177///death receptor agonist activity+++GO:0048018///receptor ligand activity GO:0001942///hair follicle development+++GO:0006955///immune response+++GO:0007160///cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043473///pigmentation+++GO:0043588///skin development+++GO:0048513///animal organ development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060662///salivary gland cavitation+++GO:0060789///hair follicle placode formation+++GO:0061153///trachea gland development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 13608 13608 'Edar' mRNA 24 19 21 0.36 0.29 0.35 0.22 0.24 0.1 0.333333333 0.186666667 17 18 7 21.33333333 14 0.382431704 -0.621007454 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell GO:0004888///transmembrane signaling receptor activity+++GO:0038023///signaling receptor activity GO:0001942///hair follicle development+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043473///pigmentation+++GO:0046330///positive regulation of JNK cascade+++GO:0060662///salivary gland cavitation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 13609 13609 'S1pr1' mRNA 1881 1995 1851 34.09 35.58 35.58 28.68 31.54 28.89 35.08333333 29.70333333 1821 1956 1776 1909 1851 0.574331379 -0.05517304 04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001664///G protein-coupled receptor binding+++GO:0004930///G protein-coupled receptor activity+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0046625///sphingolipid binding GO:0001525///angiogenesis+++GO:0001955///blood vessel maturation+++GO:0003245///cardiac muscle tissue growth involved in heart morphogenesis+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0016477///cell migration+++GO:0019222///regulation of metabolic process+++GO:0019226///transmission of nerve impulse+++GO:0030032///lamellipodium assembly+++GO:0030155///regulation of cell adhesion+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030500///regulation of bone mineralization+++GO:0030595///leukocyte chemotaxis+++GO:0031532///actin cytoskeleton reorganization+++GO:0043547///positive regulation of GTPase activity+++GO:0045124///regulation of bone resorption+++GO:0045446///endothelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051497///negative regulation of stress fiber assembly+++GO:0061384///heart trabecula morphogenesis+++GO:0072678///T cell migration 13610 13610 'S1pr3' mRNA 228 245 231 2.73 2.88 2.93 3.89 3.6 3.74 2.846666667 3.743333333 374 338 348 234.6666667 353.3333333 9.85E-05 0.578084757 04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005178///integrin binding+++GO:0038036///sphingosine-1-phosphate receptor activity GO:0001816///cytokine production+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0032651///regulation of interleukin-1 beta production+++GO:1903141///negative regulation of establishment of endothelial barrier 13611 13611 'S1pr4' mRNA 57 54 59 1.33 1.24 1.46 2.03 1.89 1.81 1.343333333 1.91 100 91 86 56.66666667 92.33333333 0.020376016 0.690052661 04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0038036///sphingosine-1-phosphate receptor activity GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process 13612 13612 'Edil3' mRNA 153 152 152 1.52 1.49 1.6 0.89 0.99 0.83 1.536666667 0.903333333 103 112 93 152.3333333 102.6666667 0.011190168 -0.581136603 GO:0005576///extracellular region GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0010811///positive regulation of cell-substrate adhesion 13614 13614 'Edn1' mRNA 63 67 51 1.67 1.74 1.43 2.62 2.94 2.92 1.613333333 2.826666667 114 125 123 60.33333333 120.6666667 1.74E-04 0.993136889 04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++04668///TNF signaling pathway+++04916///Melanogenesis+++04924///Renin secretion+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++05410///Hypertrophic cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0033093///Weibel-Palade body+++GO:0045178///basal part of cell+++GO:0048237///rough endoplasmic reticulum lumen GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0031707///endothelin A receptor binding+++GO:0031708///endothelin B receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001501///skeletal system development+++GO:0001516///prostaglandin biosynthetic process+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001821///histamine secretion+++GO:0001975///response to amphetamine+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0003357///noradrenergic neuron differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0006885///regulation of pH+++GO:0007005///mitochondrion organization+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007267///cell-cell signaling+++GO:0007507///heart development+++GO:0007585///respiratory gaseous exchange+++GO:0007589///body fluid secretion+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0009953///dorsal/ventral pattern formation+++GO:0010193///response to ozone+++GO:0010259///multicellular organism aging+++GO:0010460///positive regulation of heart rate+++GO:0010467///gene expression+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010629///negative regulation of gene expression+++GO:0010737///protein kinase A signaling+++GO:0010827///regulation of glucose transmembrane transport+++GO:0014032///neural crest cell development+++GO:0014033///neural crest cell differentiation+++GO:0014034///neural crest cell fate commitment+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0014824///artery smooth muscle contraction+++GO:0014826///vein smooth muscle contraction+++GO:0019229///regulation of vasoconstriction+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0030072///peptide hormone secretion+++GO:0030185///nitric oxide transport+++GO:0030335///positive regulation of cell migration+++GO:0030878///thyroid gland development+++GO:0031175///neuron projection development+++GO:0031583///phospholipase D-activating G protein-coupled receptor signaling pathway+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0033574///response to testosterone+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0034696///response to prostaglandin F+++GO:0035050///embryonic heart tube development+++GO:0035094///response to nicotine+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0035810///positive regulation of urine volume+++GO:0035815///positive regulation of renal sodium excretion+++GO:0035994///response to muscle stretch+++GO:0042045///epithelial fluid transport+++GO:0042310///vasoconstriction+++GO:0042313///protein kinase C deactivation+++GO:0042474///middle ear morphogenesis+++GO:0042482///positive regulation of odontogenesis+++GO:0042493///response to drug+++GO:0042554///superoxide anion generation+++GO:0043179///rhythmic excitation+++GO:0043200///response to amino acid+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0044321///response to leptin+++GO:0044751///cellular response to human chorionic gonadotropin stimulus+++GO:0045793///positive regulation of cell size+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046887///positive regulation of hormone secretion+++GO:0046888///negative regulation of hormone secretion+++GO:0048016///inositol phosphate-mediated signaling+++GO:0048514///blood vessel morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048675///axon extension+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051216///cartilage development+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0051899///membrane depolarization+++GO:0051930///regulation of sensory perception of pain+++GO:0060070///canonical Wnt signaling pathway+++GO:0060137///maternal process involved in parturition+++GO:0060298///positive regulation of sarcomere organization+++GO:0060385///axonogenesis involved in innervation+++GO:0060585///positive regulation of prostaglandin-endoperoxide synthase activity+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0070101///positive regulation of chemokine-mediated signaling pathway+++GO:0070294///renal sodium ion absorption+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071310///cellular response to organic substance+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071389///cellular response to mineralocorticoid stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071456///cellular response to hypoxia+++GO:0071548///response to dexamethasone+++GO:0071559///response to transforming growth factor beta+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0086100///endothelin receptor signaling pathway+++GO:0086101///endothelin receptor signaling pathway involved in heart process+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0097492///sympathetic neuron axon guidance+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902074///response to salt+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1903537///meiotic cell cycle process involved in oocyte maturation+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000273///positive regulation of signaling receptor activity+++GO:2001259///positive regulation of cation channel activity 13615 13615 'Edn2' mRNA 2 2 3 0.08 0.08 0.13 0.21 0.33 0.37 0.096666667 0.303333333 6 9 10 2.333333333 8.333333333 0.128325604 1.822131627 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++04924///Renin secretion GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031708///endothelin B receptor binding GO:0001516///prostaglandin biosynthetic process+++GO:0001525///angiogenesis+++GO:0001543///ovarian follicle rupture+++GO:0001659///temperature homeostasis+++GO:0001944///vasculature development+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0006874///cellular calcium ion homeostasis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009932///cell tip growth+++GO:0010460///positive regulation of heart rate+++GO:0014824///artery smooth muscle contraction+++GO:0014826///vein smooth muscle contraction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019229///regulation of vasoconstriction+++GO:0019722///calcium-mediated signaling+++GO:0030593///neutrophil chemotaxis+++GO:0031175///neuron projection development+++GO:0042116///macrophage activation+++GO:0042310///vasoconstriction+++GO:0043542///endothelial cell migration+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046887///positive regulation of hormone secretion+++GO:0046888///negative regulation of hormone secretion+++GO:0048016///inositol phosphate-mediated signaling+++GO:0048246///macrophage chemotaxis+++GO:0048286///lung alveolus development+++GO:0048675///axon extension+++GO:0060585///positive regulation of prostaglandin-endoperoxide synthase activity+++GO:0097009///energy homeostasis 13616 13616 'Edn3' mRNA 178 137 158 3.13 2.37 2.95 3.16 2.36 3.08 2.816666667 2.866666667 207 151 195 157.6666667 184.3333333 0.393985124 0.21006301 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++04924///Renin secretion GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031708///endothelin B receptor binding GO:0001755///neural crest cell migration+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0006874///cellular calcium ion homeostasis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007411///axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0010468///regulation of gene expression+++GO:0010961///cellular magnesium ion homeostasis+++GO:0014826///vein smooth muscle contraction+++GO:0019229///regulation of vasoconstriction+++GO:0030072///peptide hormone secretion+++GO:0030182///neuron differentiation+++GO:0030318///melanocyte differentiation+++GO:0030334///regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0031175///neuron projection development+++GO:0042310///vasoconstriction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045597///positive regulation of cell differentiation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0046887///positive regulation of hormone secretion+++GO:0046888///negative regulation of hormone secretion+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048016///inositol phosphate-mediated signaling+++GO:0048070///regulation of developmental pigmentation+++GO:0048675///axon extension+++GO:0060585///positive regulation of prostaglandin-endoperoxide synthase activity+++GO:1901381///positive regulation of potassium ion transmembrane transport 13617 13617 'Ednra' mRNA 218 213 219 3.25 3.12 3.46 1.72 1.23 1.27 3.276666667 1.406666667 133 93 95 216.6666667 107 7.69E-07 -1.033688734 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++04924///Renin secretion+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0045121///membrane raft+++GO:0071944///cell periphery GO:0004713///protein tyrosine kinase activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004962///endothelin receptor activity+++GO:0005515///protein binding "GO:0000278///mitotic cell cycle+++GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001821///histamine secretion+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001974///blood vessel remodeling+++GO:0001975///response to amphetamine+++GO:0002027///regulation of heart rate+++GO:0003094///glomerular filtration+++GO:0003207///cardiac chamber formation+++GO:0003220///left ventricular cardiac muscle tissue morphogenesis+++GO:0003228///atrial cardiac muscle tissue development+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0003357///noradrenergic neuron differentiation+++GO:0006468///protein phosphorylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007266///Rho protein signal transduction+++GO:0007382///specification of segmental identity, maxillary segment+++GO:0007411///axon guidance+++GO:0007507///heart development+++GO:0007585///respiratory gaseous exchange+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0010033///response to organic substance+++GO:0010259///multicellular organism aging+++GO:0010467///gene expression+++GO:0010737///protein kinase A signaling+++GO:0010827///regulation of glucose transmembrane transport+++GO:0014032///neural crest cell development+++GO:0014033///neural crest cell differentiation+++GO:0014034///neural crest cell fate commitment+++GO:0014824///artery smooth muscle contraction+++GO:0016322///neuron remodeling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019233///sensory perception of pain+++GO:0030202///heparin metabolic process+++GO:0030878///thyroid gland development+++GO:0031175///neuron projection development+++GO:0032496///response to lipopolysaccharide+++GO:0032835///glomerulus development+++GO:0034599///cellular response to oxidative stress+++GO:0035050///embryonic heart tube development+++GO:0035904///aorta development+++GO:0042305///specification of segmental identity, mandibular segment+++GO:0042310///vasoconstriction+++GO:0042415///norepinephrine metabolic process+++GO:0042474///middle ear morphogenesis+++GO:0042482///positive regulation of odontogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043084///penile erection+++GO:0043278///response to morphine+++GO:0044751///cellular response to human chorionic gonadotropin stimulus+++GO:0048144///fibroblast proliferation+++GO:0048484///enteric nervous system development+++GO:0048485///sympathetic nervous system development+++GO:0048659///smooth muscle cell proliferation+++GO:0048675///axon extension+++GO:0048706///embryonic skeletal system development+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050905///neuromuscular process+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051928///positive regulation of calcium ion transport+++GO:0055078///sodium ion homeostasis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060322///head development+++GO:0060324///face development+++GO:0060385///axonogenesis involved in innervation+++GO:0061028///establishment of endothelial barrier+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0070294///renal sodium ion absorption+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0071260///cellular response to mechanical stimulus+++GO:0071310///cellular response to organic substance+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071806///protein transmembrane transport+++GO:0072011///glomerular endothelium development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0086100///endothelin receptor signaling pathway+++GO:0086101///endothelin receptor signaling pathway involved in heart process+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090184///positive regulation of kidney development+++GO:0097018///renal albumin absorption+++GO:0097084///vascular smooth muscle cell development+++GO:0097152///mesenchymal cell apoptotic process+++GO:0097492///sympathetic neuron axon guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1903210///glomerular visceral epithelial cell apoptotic process+++GO:1903537///meiotic cell cycle process involved in oocyte maturation+++GO:1904888///cranial skeletal system development+++GO:1905144///response to acetylcholine+++GO:1905871///regulation of protein localization to cell leading edge+++GO:2001259///positive regulation of cation channel activity" 13618 13618 'Ednrb' mRNA 2119 2282 2329 32.5 33.91 37.18 28.46 25.91 27.12 34.53 27.16333333 2062 1851 1900 2243.333333 1937.666667 0.007297372 -0.226031973 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04916///Melanogenesis+++04926///Relaxin signaling pathway+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0045121///membrane raft GO:0004930///G protein-coupled receptor activity+++GO:0004962///endothelin receptor activity+++GO:0005515///protein binding+++GO:0017046///peptide hormone binding+++GO:0031702///type 1 angiotensin receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002001///renin secretion into blood stream+++GO:0002027///regulation of heart rate+++GO:0006885///regulation of pH+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007422///peripheral nervous system development+++GO:0007497///posterior midgut development+++GO:0007568///aging+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010467///gene expression+++GO:0014043///negative regulation of neuron maturation+++GO:0014070///response to organic cyclic compound+++GO:0014826///vein smooth muscle contraction+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0030202///heparin metabolic process+++GO:0030318///melanocyte differentiation+++GO:0031620///regulation of fever generation+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0032341///aldosterone metabolic process+++GO:0032496///response to lipopolysaccharide+++GO:0035645///enteric smooth muscle cell differentiation+++GO:0035810///positive regulation of urine volume+++GO:0035812///renal sodium excretion+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042045///epithelial fluid transport+++GO:0042310///vasoconstriction+++GO:0042311///vasodilation+++GO:0043066///negative regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0048246///macrophage chemotaxis+++GO:0048265///response to pain+++GO:0048484///enteric nervous system development+++GO:0050678///regulation of epithelial cell proliferation+++GO:0051930///regulation of sensory perception of pain+++GO:0055078///sodium ion homeostasis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060406///positive regulation of penile erection+++GO:0060465///pharynx development+++GO:0061028///establishment of endothelial barrier+++GO:0070294///renal sodium ion absorption+++GO:0070588///calcium ion transmembrane transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071806///protein transmembrane transport+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0086100///endothelin receptor signaling pathway+++GO:0097018///renal albumin absorption+++GO:1904383///response to sodium phosphate+++GO:1990839///response to endothelin 13619 13619 'Phc1' mRNA 546 584 487 7.58 7.89 7.17 5.14 4.99 5.06 7.546666667 5.063333333 419 398 400 539 405.6666667 5.30E-04 -0.419413322 GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0016574///histone ubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071300///cellular response to retinoic acid+++GO:1990830///cellular response to leukemia inhibitory factor" 13626 13626 'Eed' mRNA 575 620 384 15.84 16.83 11.22 12.84 12.93 14.48 14.63 13.41666667 536 527 585 526.3333333 549.3333333 0.766072977 0.059187645 GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0035098///ESC/E(Z) complex+++GO:0045120///pronucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0031491///nucleosome binding+++GO:0042054///histone methyltransferase activity+++GO:0042802///identical protein binding+++GO:0046976///histone methyltransferase activity (H3-K27 specific) GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0016571///histone methylation+++GO:0021510///spinal cord development+++GO:0031507///heterochromatin assembly+++GO:0048709///oligodendrocyte differentiation+++GO:0050790///regulation of catalytic activity+++GO:0061087///positive regulation of histone H3-K27 methylation+++GO:0070734///histone H3-K27 methylation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000011///regulation of adaxial/abaxial pattern formation 13627 13627 'Eef1a1' mRNA 42527.42 41976.01 39920.18 1370.27 1332.99 1364.55 1731.7 1622.75 1721.1 1355.936667 1691.85 61770.51 56498.75 59411.01 41474.53667 59226.75667 2.46E-28 0.501941604 03013///Nucleocytoplasmic transport+++05134///Legionellosis+++05140///Leishmaniasis GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0032587///ruffle membrane+++GO:0043209///myelin sheath GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003729///mRNA binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:1901363///heterocyclic compound binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0010942///positive regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1900022///regulation of D-erythro-sphingosine kinase activity+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process 13628 13628 'Eef1a2' mRNA 6.56 3 7 0.04 0.02 0.05 0.03 0.03 0.02 0.036666667 0.026666667 5 5 2.94 5.52 4.313333333 0.773395844 -0.439832103 03013///Nucleocytoplasmic transport+++05134///Legionellosis+++05140///Leishmaniasis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005853///eukaryotic translation elongation factor 1 complex+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0010035///response to inorganic substance+++GO:0043065///positive regulation of apoptotic process+++GO:0051602///response to electrical stimulus+++GO:0090218///positive regulation of lipid kinase activity 13629 13629 'Eef2' mRNA 12488 13030 11721 220.78 226.68 219.81 232.02 215.36 226.23 222.4233333 224.5366667 15101 13690 14258 12413 14349.66667 7.79E-05 0.197910042 04152///AMPK signaling pathway+++04921///Oxytocin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005886///plasma membrane+++GO:0016235///aggresome+++GO:0042788///polysomal ribosome+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0003723///RNA binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008097///5S rRNA binding+++GO:0019901///protein kinase binding+++GO:0043022///ribosome binding+++GO:0051015///actin filament binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002931///response to ischemia+++GO:0003009///skeletal muscle contraction+++GO:0006412///translation+++GO:0006414///translational elongation+++GO:0007568///aging+++GO:0014009///glial cell proliferation+++GO:0032355///response to estradiol+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035914///skeletal muscle cell differentiation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0045471///response to ethanol+++GO:0045727///positive regulation of translation+++GO:0051593///response to folic acid+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000767///positive regulation of cytoplasmic translation 13631 13631 'Eef2k' mRNA 619 656 668 5.19 5.39 5.93 4.07 3.51 4.33 5.503333333 3.97 562 472 578 647.6666667 537.3333333 0.025451199 -0.283868904 04152///AMPK signaling pathway+++04921///Oxytocin signaling pathway GO:0014069///postsynaptic density+++GO:0043197///dendritic spine "GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004686///elongation factor-2 kinase activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008135///translation factor activity, RNA binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity" GO:0002931///response to ischemia+++GO:0006414///translational elongation+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0031952///regulation of protein autophosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0045807///positive regulation of endocytosis+++GO:0046777///protein autophosphorylation+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071277///cellular response to calcium ion+++GO:0071320///cellular response to cAMP+++GO:0071454///cellular response to anoxia+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:1990637///response to prolactin 13636 13636 'Efna1' mRNA 1268 1362 1237 50.61 53.62 52.38 46.95 46.08 46.55 52.20333333 46.52666667 1351 1294 1296 1289 1313.666667 0.875072464 0.016167661 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0043022///ribosome binding+++GO:0046875///ephrin receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003180///aortic valve morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003199///endocardial cushion to mesenchymal transition involved in heart valve formation+++GO:0006412///translation+++GO:0006414///translational elongation+++GO:0007411///axon guidance+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0014028///notochord formation+++GO:0016477///cell migration+++GO:0030182///neuron differentiation+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0043409///negative regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043535///regulation of blood vessel endothelial cell migration+++GO:0045765///regulation of angiogenesis+++GO:0046039///GTP metabolic process+++GO:0048013///ephrin receptor signaling pathway+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050770///regulation of axonogenesis+++GO:0050821///protein stabilization+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process 13637 13637 'Efna2' mRNA 147 155 151 3.9 4.05 4.25 2.82 3.62 2.29 4.066666667 2.91 122 153 96 151 123.6666667 0.260429239 -0.298944813 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031594///neuromuscular junction+++GO:0043204///perikaryon "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046875///ephrin receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001817///regulation of cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007411///axon guidance+++GO:0021772///olfactory bulb development+++GO:0030154///cell differentiation+++GO:0030316///osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046849///bone remodeling+++GO:0048013///ephrin receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway" 13638 13638 'Efna3' mRNA 164 97 79 3.92 2.29 2.01 1.71 1.54 1.75 2.74 1.666666667 81 73 81 113.3333333 78.33333333 0.095600966 -0.537363781 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++05206///MicroRNAs in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0046875///ephrin receptor binding GO:0007411///axon guidance+++GO:0016525///negative regulation of angiogenesis+++GO:0045664///regulation of neuron differentiation+++GO:0048013///ephrin receptor signaling pathway+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 13639 13639 'Efna4' mRNA 174 130 126 6.38 4.7 4.9 6.61 4.12 5.97 5.326666667 5.566666667 207 126 181 143.3333333 171.3333333 0.371282796 0.244368608 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++05206///MicroRNAs in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0046875///ephrin receptor binding GO:0007411///axon guidance+++GO:0048013///ephrin receptor signaling pathway 13640 13640 'Efna5' mRNA 2507 2732 2502 25.5 27.31 26.97 16.08 16.54 16.08 26.59333333 16.23333333 1818 1827 1763 2580.333333 1802.666667 2.03E-14 -0.528561416 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++05206///MicroRNAs in cancer GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0071944///cell periphery+++GO:0098982///GABA-ergic synapse GO:0005169///neurotrophin TRKB receptor binding+++GO:0005515///protein binding+++GO:0045499///chemorepellent activity+++GO:0046875///ephrin receptor binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0022407///regulation of cell-cell adhesion+++GO:0022604///regulation of cell morphogenesis+++GO:0030154///cell differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043087///regulation of GTPase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0048668///collateral sprouting+++GO:0048672///positive regulation of collateral sprouting+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050919///negative chemotaxis+++GO:0051893///regulation of focal adhesion assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0099560///synaptic membrane adhesion+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1904322///cellular response to forskolin 13641 13641 'Efnb1' mRNA 846 802 274 13.74 12.81 4.72 3.4 6.41 5.45 10.42333333 5.086666667 241 444 374 640.6666667 353 0.164808856 -0.843350886 04360///Axon guidance GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding+++GO:0046875///ephrin receptor binding GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0009880///embryonic pattern specification+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0042102///positive regulation of T cell proliferation+++GO:0048013///ephrin receptor signaling pathway+++GO:0099054///presynapse assembly 13642 13642 'Efnb2' mRNA 719 778 468 6.21 6.59 4.37 3.33 2.8 3.23 5.723333333 3.12 412 323 398 655 377.6666667 4.35E-07 -0.797888691 04360///Axon guidance GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0046875///ephrin receptor binding GO:0001525///angiogenesis+++GO:0001945///lymph vessel development+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0034332///adherens junction organization+++GO:0048013///ephrin receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0048845///venous blood vessel morphogenesis+++GO:0050920///regulation of chemotaxis+++GO:0072178///nephric duct morphogenesis+++GO:0099054///presynapse assembly+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1901216///positive regulation of neuron death+++GO:1903849///positive regulation of aorta morphogenesis+++GO:2000727///positive regulation of cardiac muscle cell differentiation 13643 13643 'Efnb3' mRNA 119 109 92 2 1.81 1.66 2.04 1.45 1.62 1.823333333 1.703333333 139 96 106 106.6666667 113.6666667 0.81792072 0.080295121 04360///Axon guidance GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0046875///ephrin receptor binding "GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007628///adult walking behavior+++GO:0016198///axon choice point recognition+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0048013///ephrin receptor signaling pathway+++GO:0050771///negative regulation of axonogenesis+++GO:0099557///trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission" 13644 13644 'Efs' mRNA 1183.68 1185.55 1132.08 18.12 17.87 18.44 12.56 13.29 13.29 18.14333333 13.04666667 941.23 978.1 967.42 1167.103333 962.25 0.001119718 -0.289315559 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016477///cell migration+++GO:0090527///actin filament reorganization 13645 13645 'Egf' mRNA 1215 1223 1325 13.73 13.56 15.87 4.5 4.54 4.26 14.38666667 4.433333333 457 451 416 1254.333333 441.3333333 3.80E-48 -1.521799674 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++05160///Hepatitis C+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05226///Gastric cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity "GO:0000186///activation of MAPKK activity+++GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002092///positive regulation of receptor internalization+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021940///positive regulation of cerebellar granule cell precursor proliferation+++GO:0030335///positive regulation of cell migration+++GO:0038029///epidermal growth factor receptor signaling pathway via MAPK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045740///positive regulation of DNA replication+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046425///regulation of JAK-STAT cascade+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050708///regulation of protein secretion+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051048///negative regulation of secretion+++GO:0051223///regulation of protein transport+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060749///mammary gland alveolus development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090279///regulation of calcium ion import+++GO:0090370///negative regulation of cholesterol efflux+++GO:1900127///positive regulation of hyaluronan biosynthetic process+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1905278///positive regulation of epithelial tube formation+++GO:2000008///regulation of protein localization to cell surface+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000573///positive regulation of DNA biosynthetic process" 13646 13646 'Klk1b22' mRNA 1 1 0 0.08 0.08 0 0.07 0.28 0 0.053333333 0.116666667 1 4 0 0.666666667 1.666666667 0.671413122 1.348200574 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 13649 13649 'Egfr' mRNA 1523 1602 1680 15.7 17.19 18.52 13.99 12.89 14.14 17.13666667 13.67333333 1442 1224 1379 1601.666667 1348.333333 0.005802828 -0.263856928 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04214///Apoptosis - fly+++04320///Dorso-ventral axis formation+++04510///Focal adhesion+++04520///Adherens junction+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05131///Shigellosis+++05160///Hepatitis C+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer" "GO:0000139///Golgi membrane+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031901///early endosome membrane+++GO:0031965///nuclear membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097489///multivesicular body, internal vesicle lumen+++GO:0097708///intracellular vesicle" GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005006///epidermal growth factor-activated receptor activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0048408///epidermal growth factor binding+++GO:0051015///actin filament binding "GO:0000186///activation of MAPKK activity+++GO:0000902///cell morphogenesis+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0006412///translation+++GO:0006468///protein phosphorylation+++GO:0006970///response to osmotic stress+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007435///salivary gland morphogenesis+++GO:0007494///midgut development+++GO:0007611///learning or memory+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0010750///positive regulation of nitric oxide mediated signal transduction+++GO:0010960///magnesium ion homeostasis+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0014070///response to organic cyclic compound+++GO:0016101///diterpenoid metabolic process+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021795///cerebral cortex cell migration+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0032355///response to estradiol+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033590///response to cobalamin+++GO:0033594///response to hydroxyisoflavone+++GO:0033674///positive regulation of kinase activity+++GO:0033993///response to lipid+++GO:0034614///cellular response to reactive oxygen species+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042311///vasodilation+++GO:0042327///positive regulation of phosphorylation+++GO:0042698///ovulation cycle+++GO:0042743///hydrogen peroxide metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043586///tongue development+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045739///positive regulation of DNA repair+++GO:0045740///positive regulation of DNA replication+++GO:0045780///positive regulation of bone resorption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046328///regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048143///astrocyte activation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048546///digestive tract morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048812///neuron projection morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0051592///response to calcium ion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060571///morphogenesis of an epithelial fold+++GO:0061029///eyelid development in camera-type eye+++GO:0070141///response to UV-A+++GO:0070257///positive regulation of mucus secretion+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071230///cellular response to amino acid stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0071276///cellular response to cadmium ion+++GO:0071363///cellular response to growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097421///liver regeneration+++GO:0098609///cell-cell adhesion+++GO:1900020///positive regulation of protein kinase C activity+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902722///positive regulation of prolactin secretion+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1905208///negative regulation of cardiocyte differentiation" 13650 13650 'Rhbdf1' mRNA 400 398 350 7.56 7.47 7.07 11.32 11.31 9.99 7.366666667 10.87333333 691 670 587 382.6666667 649.3333333 2.25E-10 0.752705256 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity GO:0006508///proteolysis+++GO:0008283///cell proliferation+++GO:0016477///cell migration+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0050708///regulation of protein secretion+++GO:0050709///negative regulation of protein secretion+++GO:0061136///regulation of proteasomal protein catabolic process 13653 13653 'Egr1' mRNA 1320 1328 1343 23.56 23.33 25.43 32.36 33.25 33.98 24.10666667 33.19666667 2086 2093 2121 1330.333333 2100 1.17E-17 0.64605742 "04371///Apelin signaling pathway+++04912///GnRH signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04933///AGE-RAGE signaling pathway in diabetic complications+++05020///Prion disease+++05166///Human T-cell leukemia virus 1 infection" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044729///hemi-methylated DNA-binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0002931///response to ischemia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007611///learning or memory+++GO:0007616///long-term memory+++GO:0009749///response to glucose+++GO:0010628///positive regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030217///T cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0033233///regulation of protein sumoylation+++GO:0035914///skeletal muscle cell differentiation+++GO:0042981///regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0044849///estrous cycle+++GO:0045475///locomotor rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046886///positive regulation of hormone biosynthetic process+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048511///rhythmic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0060086///circadian temperature homeostasis+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0071310///cellular response to organic substance+++GO:0071480///cellular response to gamma radiation+++GO:0071504///cellular response to heparin+++GO:0071506///cellular response to mycophenolic acid+++GO:0072110///glomerular mesangial cell proliferation+++GO:0072303///positive regulation of glomerular metanephric mesangial cell proliferation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0098759///cellular response to interleukin-8+++GO:1901216///positive regulation of neuron death+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:2000182///regulation of progesterone biosynthetic process" 13654 13654 'Egr2' mRNA 1007.92 1033.35 996.31 18.52 18.82 19.85 27.15 29.06 25.27 19.06333333 27.16 1634.42 1756.21 1491.8 1012.526667 1627.476667 4.59E-14 0.673685689 04625///C-type lectin receptor signaling pathway+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061665///SUMO ligase activity+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006611///protein export from nucleus+++GO:0007611///learning or memory+++GO:0007622///rhythmic behavior+++GO:0008045///motor neuron axon guidance+++GO:0010467///gene expression+++GO:0014037///Schwann cell differentiation+++GO:0014040///positive regulation of Schwann cell differentiation+++GO:0016925///protein sumoylation+++GO:0021569///rhombomere 3 development+++GO:0021612///facial nerve structural organization+++GO:0021659///rhombomere 3 structural organization+++GO:0021660///rhombomere 3 formation+++GO:0021665///rhombomere 5 structural organization+++GO:0021666///rhombomere 5 formation+++GO:0030278///regulation of ossification+++GO:0031643///positive regulation of myelination+++GO:0032868///response to insulin+++GO:0035284///brain segmentation+++GO:0035904///aorta development+++GO:0035914///skeletal muscle cell differentiation+++GO:0042552///myelination+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0071310///cellular response to organic substance" 13655 13655 'Egr3' mRNA 10 11 6 0.13 0.15 0.09 0.85 0.62 0.49 0.123333333 0.653333333 69 50 38 9 52.33333333 8.10E-07 2.530981861 04625///C-type lectin receptor signaling pathway+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0045202///synapse "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007274///neuromuscular synaptic transmission+++GO:0007422///peripheral nervous system development+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0035767///endothelial cell chemotaxis+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045586///regulation of gamma-delta T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 13660 13660 'Ehd1' mRNA 1068 1078 980 18.36 18.24 17.87 33.56 34.31 32.84 18.15666667 33.57 2246 2243 2128 1042 2205.666667 3.20E-49 1.071422282 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0020018///ciliary pocket membrane+++GO:0030139///endocytic vesicle+++GO:0031095///platelet dense tubular network membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0010886///positive regulation of cholesterol storage+++GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0030030///cell projection organization+++GO:0031175///neuron projection development+++GO:0032456///endocytic recycling+++GO:0034383///low-density lipoprotein particle clearance+++GO:0042632///cholesterol homeostasis+++GO:0051260///protein homooligomerization+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:0072659///protein localization to plasma membrane+++GO:1901741///positive regulation of myoblast fusion+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2001137///positive regulation of endocytic recycling 13661 13661 'Ehf' mRNA 108 128 142 1.32 1.53 1.84 2.1 1.88 1.95 1.563333333 1.976666667 198 173 178 126 183 0.018273215 0.521664197 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030855///epithelial cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050673///epithelial cell proliferation" 13663 13663 'Ei24' mRNA 605 597 398 15.7 15.3 10.98 13.3 14.09 13.77 13.99333333 13.72 587 607 589 533.3333333 594.3333333 0.342354636 0.152893264 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0061676///importin-alpha family protein binding GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009410///response to xenobiotic stimulus+++GO:0016236///macroautophagy+++GO:0030308///negative regulation of cell growth+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0050885///neuromuscular process controlling balance+++GO:0071494///cellular response to UV-C+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 13664 13664 'Eif1a' mRNA 1242 1461 1322 23.64 27.42 26.72 56.94 55.33 57.46 25.92666667 56.57666667 3464 3285 3382 1341.666667 3377 3.20E-73 1.31990562 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043023///ribosomal large subunit binding GO:0006412///translation+++GO:0006413///translational initiation 13665 13665 'Eif2s1' mRNA 897 1032 958 15.58 17.64 17.65 32.8 32.85 32.47 16.95666667 32.70666667 2173 2126 2083 962.3333333 2127.333333 1.27E-45 1.132483144 04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0010494///cytoplasmic stress granule+++GO:0022627///cytosolic small ribosomal subunit+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0043614///multi-eIF complex+++GO:0044207///translation initiation ternary complex+++GO:0045202///synapse+++GO:0097451///glial limiting end-foot GO:0000049///tRNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0043022///ribosome binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0007568///aging+++GO:0009967///positive regulation of signal transduction+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032057///negative regulation of translational initiation in response to stress+++GO:0032933///SREBP signaling pathway+++GO:0034063///stress granule assembly+++GO:0034198///cellular response to amino acid starvation+++GO:0034599///cellular response to oxidative stress+++GO:0034605///cellular response to heat+++GO:0034644///cellular response to UV+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0042255///ribosome assembly+++GO:0043558///regulation of translational initiation in response to stress+++GO:0046777///protein autophosphorylation+++GO:1901216///positive regulation of neuron death+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity+++GO:1990737///response to manganese-induced endoplasmic reticulum stress+++GO:1990928///response to amino acid starvation+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process 13666 13666 'Eif2ak3' mRNA 383 396 253 4.55 4.63 3.19 3.69 3.66 3.78 4.123333333 3.71 348 341 354 344 347.6666667 0.958821904 0.011897718 04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04214///Apoptosis - fly+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05160///Hepatitis C+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0051879///Hsp90 protein binding+++GO:0071074///eukaryotic initiation factor eIF2 binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0002063///chondrocyte development+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006983///ER overload response+++GO:0006986///response to unfolded protein+++GO:0007029///endoplasmic reticulum organization+++GO:0007595///lactation+++GO:0009967///positive regulation of signal transduction+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019722///calcium-mediated signaling+++GO:0030282///bone mineralization+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031016///pancreas development+++GO:0031018///endocrine pancreas development+++GO:0031642///negative regulation of myelination+++GO:0032055///negative regulation of translation in response to stress+++GO:0032092///positive regulation of protein binding+++GO:0032933///SREBP signaling pathway+++GO:0034198///cellular response to amino acid starvation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036492///eiF2alpha phosphorylation in response to endoplasmic reticulum stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0042149///cellular response to glucose starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0046777///protein autophosphorylation+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0060734///regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070417///cellular response to cold+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902010///negative regulation of translation in response to endoplasmic reticulum stress+++GO:1902235///regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903788///positive regulation of glutathione biosynthetic process+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:1990737///response to manganese-induced endoplasmic reticulum stress 13667 13667 'Eif2b4' mRNA 922 879 844 29.58 27.88 28.66 28.54 29.26 28.28 28.70666667 28.69333333 1015 1013 975 881.6666667 1001 0.077299366 0.172001327 05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005851///eukaryotic translation initiation factor 2B complex GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031369///translation initiation factor binding GO:0001541///ovarian follicle development+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0014003///oligodendrocyte development+++GO:0042552///myelination+++GO:0043434///response to peptide hormone+++GO:0044237///cellular metabolic process+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity 13669 13669 'Eif3a' mRNA 2875 2841 2629 29.63 28.79 28.74 43.25 40.77 43.94 29.05333333 42.65333333 4831 4449 4754 2781.666667 4678 1.18E-37 0.73873546 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0043614///multi-eIF complex+++GO:0071540///eukaryotic translation initiation factor 3 complex, eIF3e+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0002188///translation reinitiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0075522///IRES-dependent viral translational initiation+++GO:0075525///viral translational termination-reinitiation 13680 13680 'Ddx19a' mRNA 437.38 458.44 348.9 8.81 9.2 7.52 7.39 7.07 8.31 8.51 7.59 412.35 385.68 450.77 414.9066667 416.2666667 0.995953615 -0.002572631 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0043065///positive regulation of apoptotic process 13681 13681 'Eif4a1' mRNA 2340 2397 2052 71.36 72.04 66.39 150.91 149.79 147.54 69.93 149.4133333 5688 5511 5382 2263 5527 6.34E-107 1.278778157 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003743///translation initiation factor activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation 13682 13682 'Eif4a2' mRNA 7860.91 7897.92 7626.87 182.79 181.03 188.28 118.29 110.88 118.76 184.0333333 115.9766667 5906.4 5414.72 5743.8 7795.233333 5688.306667 4.30E-18 -0.467094814 GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003743///translation initiation factor activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0002183///cytoplasmic translational initiation+++GO:1900260///negative regulation of RNA-directed 5'-3' RNA polymerase activity+++GO:1990830///cellular response to leukemia inhibitory factor 13684 13684 'Eif4e' mRNA 2392 2412 2525 66.12 66.26 75.34 88.94 85.37 81.13 69.24 85.14666667 3563 3324 3170 2443 3352.333333 2.88E-09 0.441986958 01521///EGFR tyrosine kinase inhibitor resistance+++04066///HIF-1 signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04211///Longevity regulating pathway+++04910///Insulin signaling pathway GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005845///mRNA cap binding complex+++GO:0010494///cytoplasmic stress granule+++GO:0016281///eukaryotic translation initiation factor 4F complex+++GO:0016442///RISC complex+++GO:0032991///protein-containing complex+++GO:0033391///chromatoid body+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031370///eukaryotic initiation factor 4G binding+++GO:0045182///translation regulator activity+++GO:0070491///repressing transcription factor binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001662///behavioral fear response+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0019827///stem cell population maintenance+++GO:0030324///lung development+++GO:0045665///negative regulation of neuron differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission" 13685 13685 'Eif4ebp1' mRNA 229 271 222 15 17.55 15.43 53.81 53.22 49.07 15.99333333 52.03333333 942 908 830 240.6666667 893.3333333 1.21E-57 1.882106752 01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04910///Insulin signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05207///Chemical carcinogenesis - receptor activation+++05221///Acute myeloid leukemia+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0005515///protein binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0030371///translation repressor activity+++GO:0031369///translation initiation factor binding+++GO:0051721///protein phosphatase 2A binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0002931///response to ischemia+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0008286///insulin receptor signaling pathway+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0031333///negative regulation of protein complex assembly+++GO:0031929///TOR signaling+++GO:0045471///response to ethanol+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045947///negative regulation of translational initiation+++GO:0071456///cellular response to hypoxia+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1990928///response to amino acid starvation 13688 13688 'Eif4ebp2' mRNA 323 317 272 10.43 10.09 9.32 11.8 11.58 13.74 9.946666667 12.37333333 420 402 473 304 431.6666667 4.26E-04 0.496773998 04213///Longevity regulating pathway - multiple species GO:0005737///cytoplasm+++GO:0098794///postsynapse GO:0005515///protein binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0030371///translation repressor activity GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0007613///memory+++GO:0008286///insulin receptor signaling pathway+++GO:0017148///negative regulation of translation+++GO:0019933///cAMP-mediated signaling+++GO:0031929///TOR signaling+++GO:0035176///social behavior+++GO:0045947///negative regulation of translational initiation+++GO:0048167///regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission 13690 13690 'Eif4g2' mRNA 10409.68 11160.76 8948.99 70.78 74.57 64.5 70.77 70.35 67.1 69.95 69.40666667 11991.99 11648.05 11014.04 10173.14333 11551.36 0.005993616 0.175293677 05416///Viral myocarditis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016281///eukaryotic translation initiation factor 4F complex+++GO:0030424///axon "GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding" GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0007507///heart development+++GO:0010507///negative regulation of autophagy+++GO:0030307///positive regulation of cell growth+++GO:0034645///cellular macromolecule biosynthetic process+++GO:0045727///positive regulation of translation+++GO:0045773///positive regulation of axon extension+++GO:0060999///positive regulation of dendritic spine development 13709 13709 'Elf1' mRNA 536.48 505.58 422.95 8.65 7.83 6.93 10.54 9.7 10.91 7.803333333 10.38333333 786.56 699.54 762.99 488.3366667 749.6966667 4.57E-08 0.609948682 04214///Apoptosis - fly GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001817///regulation of cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050860///negative regulation of T cell receptor signaling pathway" 13710 13710 'Elf3' mRNA 668 733 757 19.31 20.89 23.3 26.39 29.26 26.16 21.16666667 27.27 1045 1133 1005 719.3333333 1061 3.01E-07 0.547445101 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001824///blastocyst development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007275///multicellular organism development+++GO:0009653///anatomical structure morphogenesis+++GO:0009790///embryo development+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030855///epithelial cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060056///mammary gland involution" 13711 13711 'Elf5' mRNA 19 19 10 0.51 0.5 0.28 0.32 0.14 0.19 0.43 0.216666667 14 6 8 16 9.333333333 0.342373349 -0.784220001 04917///Prolactin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001712///ectodermal cell fate commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007398///ectoderm development+++GO:0030154///cell differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0045596///negative regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060644///mammary gland epithelial cell differentiation" 13712 13712 'Elk1' mRNA 443 464 390 6.78 6.99 6.34 4.76 4.74 4.85 6.703333333 4.783333333 358 348 353 432.3333333 353 0.025600357 -0.301722485 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04510///Focal adhesion+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++05140///Leishmaniasis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05213///Endometrial cancer+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009416///response to light stimulus+++GO:0010467///gene expression+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071394///cellular response to testosterone stimulus+++GO:0071396///cellular response to lipid+++GO:0071480///cellular response to gamma radiation+++GO:0071774///response to fibroblast growth factor+++GO:1901216///positive regulation of neuron death" 13713 13713 'Elk3' mRNA 148 123 120 1.87 1.52 1.59 6.2 5.13 5.65 1.66 5.66 565 459 494 130.3333333 506 1.60E-36 1.944721787 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0032422///purine-rich negative regulatory element binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0042060///wound healing+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 13714 13714 'Elk4' mRNA 435.14 364.89 268.01 5.24 4.34 3.43 4.51 5.37 5.3 4.336666667 5.06 424.71 501.07 487.49 356.0133333 471.09 0.017291555 0.40123195 04010///MAPK signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070932///histone H3 deacetylation" 13716 13716 'Ell' mRNA 1062 999 1040 18.87 17.47 19.61 15.26 15.1 16.03 18.65 15.46333333 988 955 1005 1033.666667 982.6666667 0.43760776 -0.085950603 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0035327///transcriptionally active chromatin+++GO:0035363///histone locus body GO:0019902///phosphatase binding GO:0001701///in utero embryonic development+++GO:0006366///transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0010923///negative regulation of phosphatase activity+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III+++GO:0045945///positive regulation of transcription by RNA polymerase III 13717 13717 'Eln' mRNA 121 115 78 1.7 1.59 1.21 0.73 0.73 0.73 1.5 0.73 59 53 56 104.6666667 56 0.001941762 -0.907202944 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0050840///extracellular matrix binding GO:0001974///blood vessel remodeling+++GO:0003151///outflow tract morphogenesis+++GO:0007519///skeletal muscle tissue development+++GO:0030198///extracellular matrix organization+++GO:0030833///regulation of actin filament polymerization+++GO:0043149///stress fiber assembly 13722 13722 'Aimp1' mRNA 498 442 460 27.64 24.24 27.09 26.9 28.31 29.32 26.32333333 28.17666667 556 572.17 586 466.6666667 571.39 0.02581973 0.280124085 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0005125///cytokine activity+++GO:0042803///protein homodimerization activity+++GO:0051020///GTPase binding GO:0001525///angiogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006412///translation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0048514///blood vessel morphogenesis+++GO:0050900///leukocyte migration+++GO:0051607///defense response to virus+++GO:0070094///positive regulation of glucagon secretion 13723 13723 'Emb' mRNA 1512 1581 1519 32 32.94 34.1 23.77 24.4 23.2 33.01333333 23.79 1292 1295 1221 1537.333333 1269.333333 4.25E-04 -0.288312 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0045202///synapse GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0035879///plasma membrane lactate transport+++GO:0070593///dendrite self-avoidance 13726 13726 'Emd' mRNA 225.96 201.08 167.12 8.39 7.4 6.61 7.93 7.3 8.21 7.466666667 7.813333333 242.33 217.78 241.87 198.0533333 233.9933333 0.247000171 0.230792329 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031616///spindle pole centrosome+++GO:0031965///nuclear membrane+++GO:0032541///cortical endoplasmic reticulum GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0048487///beta-tubulin binding GO:0035914///skeletal muscle cell differentiation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0071363///cellular response to growth factor stimulus+++GO:0071763///nuclear membrane organization+++GO:0090090///negative regulation of canonical Wnt signaling pathway 13728 13728 'Mark2' mRNA 1332 1238 1134 17.83 16.25 15.99 14.85 14.56 14.84 16.69 14.75 1294 1242 1257 1234.666667 1264.333333 0.843493863 0.024054161 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045180///basal cortex+++GO:0097427///microtubule bundle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0048156///tau protein binding+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0046777///protein autophosphorylation+++GO:0050770///regulation of axonogenesis+++GO:0051493///regulation of cytoskeleton organization+++GO:0061564///axon development+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071963///establishment or maintenance of cell polarity regulating cell shape+++GO:1904526///regulation of microtubule binding 13730 13730 'Emp1' mRNA 477 525 383 9.7 10.51 8.24 22.96 20.09 21.36 9.483333333 21.47 1299 1110 1170 461.6666667 1193 1.29E-37 1.361506616 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008219///cell death+++GO:0032060///bleb assembly 13731 13731 'Emp2' mRNA 1267.11 1178.72 1299.77 20.05 18.35 21.82 13.45 12.42 13.05 20.07333333 12.97333333 977.82 882.11 919.09 1248.533333 926.34 3.63E-06 -0.445537387 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft+++GO:0045177///apical part of cell GO:0005178///integrin binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding GO:0001765///membrane raft assembly+++GO:0001913///T cell mediated cytotoxicity+++GO:0001952///regulation of cell-matrix adhesion+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0003093///regulation of glomerular filtration+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007566///embryo implantation+++GO:0008219///cell death+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0010594///regulation of endothelial cell migration+++GO:0016477///cell migration+++GO:0032060///bleb assembly+++GO:0032147///activation of protein kinase activity+++GO:0034394///protein localization to cell surface+++GO:0043534///blood vessel endothelial cell migration+++GO:0043549///regulation of kinase activity+++GO:0045022///early endosome to late endosome transport+++GO:0045765///regulation of angiogenesis+++GO:0070252///actin-mediated cell contraction+++GO:0070836///caveola assembly+++GO:0072659///protein localization to plasma membrane+++GO:2001046///positive regulation of integrin-mediated signaling pathway+++GO:2001212///regulation of vasculogenesis 13732 13732 'Emp3' mRNA 510 455 480 46.44 41.11 46.53 285.85 299.08 292.12 44.69333333 292.35 3581 3647 3533 481.6666667 3587 6.54E-292 2.884811739 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008219///cell death+++GO:0032060///bleb assembly 13733 13733 'Adgre1' mRNA 372 304 318 6.39 5.15 5.84 57.85 60.24 55.45 5.793333333 57.84666667 3900 3975 3620 331.3333333 3831.666667 0 3.520416995 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 13796 13796 'Emx1' mRNA 2 0 0 0.11 0 0 0 0 0 0.036666667 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0009410///response to xenobiotic stimulus+++GO:0009791///post-embryonic development+++GO:0021537///telencephalon development+++GO:0021796///cerebral cortex regionalization+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021987///cerebral cortex development+++GO:0030182///neuron differentiation+++GO:0042493///response to drug+++GO:0048854///brain morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0060019///radial glial cell differentiation+++GO:0060563///neuroepithelial cell differentiation+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:1990138///neuron projection extension" 13797 13797 'Emx2' mRNA 356 300 164 7.61 6.31 3.72 1.47 1.56 1.82 5.88 1.616666667 79 82 95 273.3333333 85.33333333 1.66E-11 -1.677279448 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0009410///response to xenobiotic stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0021542///dentate gyrus development+++GO:0021796///cerebral cortex regionalization+++GO:0021846///cell proliferation in forebrain+++GO:0021885///forebrain cell migration+++GO:0021987///cerebral cortex development+++GO:0030182///neuron differentiation+++GO:0030900///forebrain development+++GO:0042493///response to drug+++GO:0072197///ureter morphogenesis" 13799 13799 'En2' mRNA 0 1 1 0 0.02 0.02 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 04341///Hedgehog signaling pathway - fly GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030182///neuron differentiation+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048666///neuron development+++GO:0071542///dopaminergic neuron differentiation+++GO:1990403///embryonic brain development" 13800 13800 'Enah' mRNA 4702.21 4760.52 4133.4 30.16 30.55 27.8 18.36 15.41 17.26 29.50333333 17.01 3164.74 2526.14 2832.78 4532.043333 2841.22 2.36E-21 -0.685059477 04015///Rap1 signaling pathway+++04360///Axon guidance+++04810///Regulation of actin cytoskeleton GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0042995///cell projection+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0017124///SH3 domain binding+++GO:0050699///WW domain binding GO:0001843///neural tube closure+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008154///actin polymerization or depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0070358///actin polymerization-dependent cell motility+++GO:1990830///cellular response to leukemia inhibitory factor 13803 13803 'Enc1' mRNA 113 87 109 1.33 0.96 1.31 1.92 1.51 1.48 1.2 1.636666667 187 146 146 103 159.6666667 0.010542099 0.615461788 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016363///nuclear matrix+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0043025///neuronal cell body GO:0003779///actin binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0017148///negative regulation of translation 13804 13804 'Endog' mRNA 214.52 261.73 53.29 13.19 15.91 3.48 3.09 2.78 5.22 10.86 3.696666667 57.67 50.57 94.17 176.5133333 67.47 0.064832041 -1.376221188 04210///Apoptosis GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0043204///perikaryon GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0001701///in utero embryonic development+++GO:0006259///DNA metabolic process+++GO:0006308///DNA catabolic process+++GO:0006309///apoptotic DNA fragmentation+++GO:0007568///aging+++GO:0009612///response to mechanical stimulus+++GO:0032355///response to estradiol+++GO:0034599///cellular response to oxidative stress+++GO:0034612///response to tumor necrosis factor+++GO:0036475///neuron death in response to oxidative stress+++GO:0043065///positive regulation of apoptotic process+++GO:0046677///response to antibiotic+++GO:0071277///cellular response to calcium ion+++GO:0071333///cellular response to glucose stimulus+++GO:0071456///cellular response to hypoxia+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:1902512///positive regulation of apoptotic DNA fragmentation" 13805 13805 'Eng' mRNA 1267 1315 1316 20.07 20.5 22.13 42.87 41.27 40.93 20.9 41.69 3113 2927 2878 1299.333333 2972.666667 1.79E-61 1.1807338 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0043235///receptor complex+++GO:0072563///endothelial microparticle GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005534///galactose binding+++GO:0005539///glycosaminoglycan binding+++GO:0015026///coreceptor activity+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0036122///BMP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0050431///transforming growth factor beta binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001837///epithelial to mesenchymal transition+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001947///heart looping+++GO:0002040///sprouting angiogenesis+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0003148///outflow tract septum morphogenesis+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003203///endocardial cushion morphogenesis+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003209///cardiac atrium morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003273///cell migration involved in endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007507///heart development+++GO:0010629///negative regulation of gene expression+++GO:0010665///regulation of cardiac muscle cell apoptotic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016477///cell migration+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0022009///central nervous system vasculogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0030336///negative regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0035912///dorsal aorta morphogenesis+++GO:0042060///wound healing+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048745///smooth muscle tissue development+++GO:0048844///artery morphogenesis+++GO:0048845///venous blood vessel morphogenesis+++GO:0048870///cell motility+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0060326///cell chemotaxis+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0070483///detection of hypoxia+++GO:0090500///endocardial cushion to mesenchymal transition+++GO:0097084///vascular smooth muscle cell development+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905065///positive regulation of vascular smooth muscle cell differentiation+++GO:1905072///cardiac jelly development+++GO:1905222///atrioventricular canal morphogenesis+++GO:1905310///regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:2000136///regulation of cell proliferation involved in heart morphogenesis" 13806 13806 'Eno1' mRNA 12680.72 13203.65 12685.89 412.13 422.94 437.37 633.76 681.98 641.69 424.1466667 652.4766667 22411.22 23538.7 21959.55 12856.75333 22636.49 3.97E-48 0.804617121 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway GO:0000015///phosphopyruvate hydratase complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0097060///synaptic membrane+++GO:0099738///cell cortex region "GO:0000287///magnesium ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0004634///phosphopyruvate hydratase activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006096///glycolytic process+++GO:0010756///positive regulation of plasminogen activation+++GO:0030308///negative regulation of cell growth+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045933///positive regulation of muscle contraction+++GO:0051099///positive regulation of binding+++GO:0061621///canonical glycolysis+++GO:0071229///cellular response to acid chemical+++GO:0098761///cellular response to interleukin-7+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:2001171///positive regulation of ATP biosynthetic process" 13807 13807 'Eno2' mRNA 1702 1665 1697 34.15 32.98 36.01 16.93 14.64 16.43 34.38 16 958 809 905 1688 890.6666667 2.17E-27 -0.936427647 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway GO:0000015///phosphopyruvate hydratase complex+++GO:0001917///photoreceptor inner segment+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0097060///synaptic membrane+++GO:0099738///cell cortex region GO:0000287///magnesium ion binding+++GO:0004634///phosphopyruvate hydratase activity+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0061621///canonical glycolysis+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death" 13808 13808 'Eno3' mRNA 509.02 458.59 339.81 11.96 9.98 9.65 10.8 10.1 8.73 10.53 9.876666667 382.98 372.56 336.53 435.8066667 364.0233333 0.101778338 -0.266427404 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway GO:0000015///phosphopyruvate hydratase complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000287///magnesium ion binding+++GO:0004634///phosphopyruvate hydratase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0006096///glycolytic process+++GO:0007568///aging+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0042493///response to drug+++GO:0043403///skeletal muscle tissue regeneration" 13809 13809 'Enpep' mRNA 21415 22522 22515 274.01 283.42 305.58 130.75 124.54 124.99 287.67 126.76 11763 10945 10891 22150.66667 11199.66667 9.24E-69 -0.997858922 04614///Renin-angiotensin system GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0045177///apical part of cell GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0001525///angiogenesis+++GO:0003081///regulation of systemic arterial blood pressure by renin-angiotensin+++GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0008283///cell proliferation+++GO:0016477///cell migration+++GO:0032835///glomerulus development+++GO:0043171///peptide catabolic process 13819 13819 'Epas1' mRNA 1711 1678 1511 17.08 16.42 15.96 17.93 16.48 16.88 16.48666667 17.09666667 2074 1862 1891 1633.333333 1942.333333 0.001487334 0.239061416 05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035035///histone acetyltransferase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0050897///cobalt ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001892///embryonic placenta development+++GO:0001974///blood vessel remodeling+++GO:0002027///regulation of heart rate+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0007275///multicellular organism development+++GO:0007601///visual perception+++GO:0010467///gene expression+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030324///lung development+++GO:0042415///norepinephrine metabolic process+++GO:0042421///norepinephrine biosynthetic process+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043129///surfactant homeostasis+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048625///myoblast fate commitment+++GO:0055072///iron ion homeostasis+++GO:0071456///cellular response to hypoxia+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903181///positive regulation of dopamine biosynthetic process+++GO:2000434///regulation of protein neddylation" 13821 13821 'Epb41l1' mRNA 1392 1451 1284 11.29 11.51 11.01 9.37 9.07 9.4 11.27 9.28 1322 1236 1295 1375.666667 1284.333333 0.213324255 -0.10963102 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0032991///protein-containing complex+++GO:0097060///synaptic membrane GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding GO:0030866///cortical actin cytoskeleton organization+++GO:0031032///actomyosin structure organization 13822 13822 'Epb41l2' mRNA 1995 2038 2071 26.5 26.6 29.28 34.41 30.83 33.71 27.46 32.98333333 3036 2646 2893 2034.666667 2858.333333 1.49E-10 0.476165511 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0008180///COP9 signalosome+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0099738///cell cortex region GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0030507///spectrin binding+++GO:0042731///PH domain binding GO:0007049///cell cycle+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0051301///cell division+++GO:1904778///positive regulation of protein localization to cell cortex 13823 13823 'Epb41l3' mRNA 941 896 925 12.9 12.07 13.39 8.44 8.62 9.61 12.78666667 8.89 717 703 780 920.6666667 733.3333333 9.54E-04 -0.340866673 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030673///axolemma+++GO:0033270///paranode region of axon+++GO:0044224///juxtaparanode region of axon GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0106006///microtubule cortical anchor activity GO:0001558///regulation of cell growth+++GO:0002175///protein localization to paranode region of axon+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0030865///cortical cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030913///paranodal junction assembly+++GO:0031032///actomyosin structure organization+++GO:0043217///myelin maintenance+++GO:0048812///neuron projection morphogenesis+++GO:0061564///axon development+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0072659///protein localization to plasma membrane+++GO:1990227///paranodal junction maintenance 13824 13824 'Epb41l4a' mRNA 905 982 961 12.22 13.27 13.8 8.49 6.77 7.18 13.09666667 7.48 667 564 589 949.3333333 606.6666667 1.77E-10 -0.660059858 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0008092///cytoskeletal protein binding GO:0031032///actomyosin structure organization 13828 13828 'Epb42' mRNA 3 1 2 0.05 0.02 0.03 0 0.07 0 0.033333333 0.023333333 0 6 0 2 2 0.998591786 0.006062201 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton GO:0003810///protein-glutamine gamma-glutamyltransferase activity GO:0000902///cell morphogenesis+++GO:0008360///regulation of cell shape+++GO:0018149///peptide cross-linking+++GO:0020027///hemoglobin metabolic process+++GO:0043249///erythrocyte maturation+++GO:0048536///spleen development+++GO:0050801///ion homeostasis+++GO:0055072///iron ion homeostasis 13829 13829 'Dmtn' mRNA 1515.42 1488.24 1256.01 29.98 29.03 26.35 8.54 9.13 8.55 28.45333333 8.74 512.02 519 493.64 1419.89 508.22 5.57E-59 -1.491105647 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0014731///spectrin-associated cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton+++GO:0031095///platelet dense tubular network membrane+++GO:0031253///cell projection membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0030507///spectrin binding+++GO:0043621///protein self-association+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0010591///regulation of lamellipodium assembly+++GO:0010763///positive regulation of fibroblast migration+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030194///positive regulation of blood coagulation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035585///calcium-mediated signaling using extracellular calcium source+++GO:0048821///erythrocyte development+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0051017///actin filament bundle assembly+++GO:0051489///regulation of filopodium assembly+++GO:0051693///actin filament capping+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0065003///protein-containing complex assembly+++GO:0070560///protein secretion by platelet+++GO:0071277///cellular response to calcium ion+++GO:0071320///cellular response to cAMP+++GO:0090303///positive regulation of wound healing+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0090527///actin filament reorganization+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901731///positive regulation of platelet aggregation+++GO:2001046///positive regulation of integrin-mediated signaling pathway 13830 13830 'Stom' mRNA 1707 1675 1745 33.45 32.31 36.27 42.69 44.35 43.33 34.01 43.45666667 2506 2543 2463 1709 2504 5.84E-13 0.53799156 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0070063///RNA polymerase binding GO:0034765///regulation of ion transmembrane transport+++GO:0044829///positive regulation by host of viral genome replication+++GO:0048524///positive regulation of viral process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1901585///regulation of acid-sensing ion channel activity 13831 13831 'Epc1' mRNA 622 552 533 11.81 11.32 11.33 8.49 7.14 7.97 11.48666667 7.866666667 472 397 426 569 431.6666667 9.96E-04 -0.410527488 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0043231///intracellular membrane-bounded organelle GO:0004402///histone acetyltransferase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051155///positive regulation of striated muscle cell differentiation" 13835 13835 'Epha1' mRNA 1221.91 1172.12 895.67 21.07 19.53 16.24 3.47 4.05 5.02 18.94666667 4.18 230.16 272.58 323 1096.566667 275.2466667 1.97E-49 -1.998923414 04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0001968///fibronectin binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding GO:0001525///angiogenesis+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0033674///positive regulation of kinase activity+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043087///regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0090630///activation of GTPase activity 13836 13836 'Epha2' mRNA 65 68 69 0.91 0.93 1.15 3.24 2.49 2.41 0.996666667 2.713333333 246 182 175 67.33333333 201 1.33E-11 1.562206299 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031256///leading edge membrane+++GO:0031258///lamellipodium membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0070160///tight junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding GO:0001501///skeletal system development+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001649///osteoblast differentiation+++GO:0001818///negative regulation of cytokine production+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010591///regulation of lamellipodium assembly+++GO:0014028///notochord formation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021915///neural tube development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030316///osteoclast differentiation+++GO:0032682///negative regulation of chemokine production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0033674///positive regulation of kinase activity+++GO:0036342///post-anal tail morphogenesis+++GO:0043491///protein kinase B signaling+++GO:0043535///regulation of blood vessel endothelial cell migration+++GO:0045765///regulation of angiogenesis+++GO:0046058///cAMP metabolic process+++GO:0046849///bone remodeling+++GO:0048013///ephrin receptor signaling pathway+++GO:0048320///axial mesoderm formation+++GO:0048514///blood vessel morphogenesis+++GO:0048570///notochord morphogenesis+++GO:0048870///cell motility+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060035///notochord cell development+++GO:0060326///cell chemotaxis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0070309///lens fiber cell morphogenesis+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070848///response to growth factor+++GO:0072659///protein localization to plasma membrane+++GO:0090630///activation of GTPase activity+++GO:1901491///negative regulation of lymphangiogenesis+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:1904238///pericyte cell differentiation 13837 13837 'Epha3' mRNA 65 61 54 0.61 0.56 0.54 0.17 0.12 0.21 0.57 0.166666667 21 14 25 60 20 1.05E-04 -1.595830862 04360///Axon guidance GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0098793///presynapse+++GO:0098982///GABA-ergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding GO:0003197///endocardial cushion development+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030334///regulation of cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033674///positive regulation of kinase activity+++GO:0043087///regulation of GTPase activity+++GO:0045806///negative regulation of endocytosis+++GO:0048013///ephrin receptor signaling pathway+++GO:0051893///regulation of focal adhesion assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071300///cellular response to retinoic acid+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0097155///fasciculation of sensory neuron axon+++GO:0097156///fasciculation of motor neuron axon+++GO:0099560///synaptic membrane adhesion+++GO:1903078///positive regulation of protein localization to plasma membrane 13838 13838 'Epha4' mRNA 882 986 915 7.38 8.12 8.12 3.37 2.74 3.01 7.873333333 3.04 464 369 401 927.6666667 411.3333333 9.20E-27 -1.186763903 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043235///receptor complex+++GO:0043679///axon terminus+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042731///PH domain binding+++GO:0042802///identical protein binding+++GO:0046875///ephrin receptor binding+++GO:0097161///DH domain binding+++GO:1990782///protein tyrosine kinase binding GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007628///adult walking behavior+++GO:0008045///motor neuron axon guidance+++GO:0008347///glial cell migration+++GO:0010977///negative regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021957///corticospinal tract morphogenesis+++GO:0030336///negative regulation of cell migration+++GO:0033674///positive regulation of kinase activity+++GO:0034332///adherens junction organization+++GO:0043087///regulation of GTPase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0048681///negative regulation of axon regeneration+++GO:0048710///regulation of astrocyte differentiation+++GO:0050770///regulation of axonogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050821///protein stabilization+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0072178///nephric duct morphogenesis+++GO:0090102///cochlea development+++GO:0097155///fasciculation of sensory neuron axon+++GO:0097156///fasciculation of motor neuron axon+++GO:0097485///neuron projection guidance+++GO:0098883///synapse pruning+++GO:0106030///neuron projection fasciculation+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process+++GO:1904646///cellular response to amyloid-beta+++GO:1905244///regulation of modification of synaptic structure+++GO:2001108///positive regulation of Rho guanyl-nucleotide exchange factor activity 13839 13839 'Epha5' mRNA 209.85 220 175 1.35 1.33 1.15 0.81 0.74 0.9 1.276666667 0.816666667 132 124 155 201.6166667 137 0.005667002 -0.563406538 04360///Axon guidance GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding GO:0006468///protein phosphorylation+++GO:0007162///negative regulation of cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0021766///hippocampus development+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033674///positive regulation of kinase activity+++GO:0043087///regulation of GTPase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0060997///dendritic spine morphogenesis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:1904322///cellular response to forskolin 13840 13840 'Epha6' mRNA 117.35 98.76 116.65 0.57 0.47 0.65 0.21 0.28 0.27 0.563333333 0.253333333 53.46 65.06 62.73 110.92 60.41666667 0.001530984 -0.891879278 04360///Axon guidance GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0048013///ephrin receptor signaling pathway 13841 13841 'Epha7' mRNA 972 930 903 11.79 10.54 11.49 9.26 8.67 9.11 11.27333333 9.013333333 908 840 896 935 881.3333333 0.36704332 -0.097179175 04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008046///axon guidance receptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0045499///chemorepellent activity+++GO:0046875///ephrin receptor binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0022407///regulation of cell-cell adhesion+++GO:0031290///retinal ganglion cell axon guidance+++GO:0031952///regulation of protein autophosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048013///ephrin receptor signaling pathway+++GO:0048671///negative regulation of collateral sprouting+++GO:0048755///branching morphogenesis of a nerve+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050919///negative chemotaxis+++GO:0051964///negative regulation of synapse assembly+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0072178///nephric duct morphogenesis+++GO:0099175///regulation of postsynapse organization 13842 13842 'Epha8' mRNA 5 0 0 0.06 0 0 0 0 0.02 0.02 0.006666667 0 0 2 1.666666667 0.666666667 0.733726654 -1.30252364 04360///Axon guidance GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding GO:0006468///protein phosphorylation+++GO:0006929///substrate-dependent cell migration+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0016322///neuron remodeling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030155///regulation of cell adhesion+++GO:0031175///neuron projection development+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0033674///positive regulation of kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0071372///cellular response to follicle-stimulating hormone stimulus 13844 13844 'Ephb2' mRNA 67 43 41 0.41 0.21 0.31 0.43 0.26 0.24 0.31 0.31 66 45 38 50.33333333 49.66666667 0.95317325 -0.031008941 04360///Axon guidance GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0000166///nucleotide binding+++GO:0001540///amyloid-beta binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008046///axon guidance receptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding "GO:0000902///cell morphogenesis+++GO:0001525///angiogenesis+++GO:0001655///urogenital system development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007162///negative regulation of cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021631///optic nerve morphogenesis+++GO:0021934///hindbrain tangential cell migration+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0022038///corpus callosum development+++GO:0030193///regulation of blood coagulation+++GO:0030335///positive regulation of cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033674///positive regulation of kinase activity+++GO:0042113///B cell activation+++GO:0042472///inner ear morphogenesis+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0048593///camera-type eye morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050771///negative regulation of axonogenesis+++GO:0050878///regulation of body fluid levels+++GO:0051489///regulation of filopodium assembly+++GO:0051963///regulation of synapse assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0060021///roof of mouth development+++GO:0060996///dendritic spine development+++GO:0060997///dendritic spine morphogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071679///commissural neuron axon guidance+++GO:0097104///postsynaptic membrane assembly+++GO:0099557///trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission+++GO:0106028///neuron projection retraction+++GO:0110077///vesicle-mediated intercellular transport+++GO:0120192///tight junction assembly+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904782///negative regulation of NMDA glutamate receptor activity+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:2000316///regulation of T-helper 17 type immune response+++GO:2000822///regulation of behavioral fear response" 13845 13845 'Ephb3' mRNA 422 418 253 5.49 5.34 3.49 3.32 3.47 3.79 4.773333333 3.526666667 294 300 325 364.3333333 306.3333333 0.201339932 -0.251471597 04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005524///ATP binding+++GO:0008046///axon guidance receptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001525///angiogenesis+++GO:0001655///urogenital system development+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0022038///corpus callosum development+++GO:0022407///regulation of cell-cell adhesion+++GO:0031290///retinal ganglion cell axon guidance+++GO:0033674///positive regulation of kinase activity+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043087///regulation of GTPase activity+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0048538///thymus development+++GO:0048546///digestive tract morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0051965///positive regulation of synapse assembly+++GO:0060021///roof of mouth development+++GO:0060996///dendritic spine development+++GO:0060997///dendritic spine morphogenesis 13846 13846 'Ephb4' mRNA 1398 1456 923 17.33 17.75 12.14 11.66 19.11 16.37 15.74 15.71333333 1083 1734 1472 1259 1429.666667 0.606629166 0.18641628 04360///Axon guidance GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001525///angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0003007///heart morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0048845///venous blood vessel morphogenesis+++GO:1903849///positive regulation of aorta morphogenesis+++GO:2000525///positive regulation of T cell costimulation 13848 13848 'Ephb6' mRNA 960 1000 994 13.87 14.19 15.23 11.94 10.54 12.26 14.43 11.58 949 818 942 984.6666667 903 0.206143593 -0.138576345 04360///Axon guidance GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005524///ATP binding GO:0001806///type IV hypersensitivity+++GO:0001816///cytokine production+++GO:0002456///T cell mediated immunity+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0032092///positive regulation of protein binding+++GO:0033674///positive regulation of kinase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0050798///activated T cell proliferation+++GO:2000525///positive regulation of T cell costimulation 13849 13849 'Ephx1' mRNA 3906 4061 3915 130.09 133.29 138.31 94.14 101.86 99.08 133.8966667 98.36 3248 3430 3309 3960.666667 3329 8.29E-05 -0.262141733 00980///Metabolism of xenobiotics by cytochrome P450+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004301///epoxide hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0033961///cis-stilbene-oxide hydrolase activity GO:0006725///cellular aromatic compound metabolic process+++GO:0009636///response to toxic substance+++GO:0014070///response to organic cyclic compound+++GO:0019369///arachidonic acid metabolic process+++GO:0019439///aromatic compound catabolic process+++GO:0034312///diol biosynthetic process+++GO:0097176///epoxide metabolic process 13850 13850 'Ephx2' mRNA 306 310 311 8.4 8.39 9.06 8.35 8.31 8.06 8.616666667 8.24 349 338 326 309 337.6666667 0.505799403 0.115264876 00590///Arachidonic acid metabolism+++04146///Peroxisome+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004301///epoxide hydrolase activity+++GO:0015643///toxic substance binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033885///10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity+++GO:0042577///lipid phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0052642///lysophosphatidic acid phosphatase activity GO:0002539///prostaglandin production involved in inflammatory response+++GO:0006629///lipid metabolic process+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0009636///response to toxic substance+++GO:0010628///positive regulation of gene expression+++GO:0016311///dephosphorylation+++GO:0019233///sensory perception of pain+++GO:0019439///aromatic compound catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043651///linoleic acid metabolic process+++GO:0045777///positive regulation of blood pressure+++GO:0046272///stilbene catabolic process+++GO:0046839///phospholipid dephosphorylation+++GO:0090181///regulation of cholesterol metabolic process+++GO:0097176///epoxide metabolic process 13852 13852 'Stx2' mRNA 277 256 179 5.35 4.83 3.68 6.14 6.44 6.59 4.62 6.39 371 382 388 237.3333333 380.3333333 3.93E-05 0.675921227 04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0030133///transport vesicle+++GO:0030496///midbody+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048787///presynaptic active zone membrane GO:0000149///SNARE binding+++GO:0005198///structural molecule activity+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding GO:0000281///mitotic cytokinesis+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0007340///acrosome reaction+++GO:0007566///embryo implantation+++GO:0016192///vesicle-mediated transport+++GO:0030033///microvillus assembly+++GO:0030154///cell differentiation+++GO:0030855///epithelial cell differentiation+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0034599///cellular response to oxidative stress+++GO:0048278///vesicle docking+++GO:0048546///digestive tract morphogenesis+++GO:0061025///membrane fusion+++GO:0061952///midbody abscission+++GO:1903575///cornified envelope assembly 13853 13853 'Epm2a' mRNA 3 2 0 0.17 0.12 0 0 0 0.05 0.096666667 0.016666667 0 0 1 1.666666667 0.333333333 0.510211753 -2.197138545 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043204///perikaryon+++GO:0098554///cytoplasmic side of endoplasmic reticulum membrane+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane GO:0004373///glycogen (starch) synthase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019203///carbohydrate phosphatase activity+++GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046983///protein dimerization activity+++GO:2001069///glycogen binding+++GO:2001070///starch binding GO:0000045///autophagosome assembly+++GO:0001558///regulation of cell growth+++GO:0001932///regulation of protein phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006470///protein dephosphorylation+++GO:0006816///calcium ion transport+++GO:0006914///autophagy+++GO:0007005///mitochondrion organization+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010923///negative regulation of phosphatase activity+++GO:0014009///glial cell proliferation+++GO:0015813///L-glutamate transmembrane transport+++GO:0016055///Wnt signaling pathway+++GO:0016239///positive regulation of macroautophagy+++GO:0016311///dephosphorylation+++GO:0031396///regulation of protein ubiquitination+++GO:0032007///negative regulation of TOR signaling+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035305///negative regulation of dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042306///regulation of protein import into nucleus+++GO:0042325///regulation of phosphorylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044260///cellular macromolecule metabolic process+++GO:0045786///negative regulation of cell cycle+++GO:0045859///regulation of protein kinase activity+++GO:0046835///carbohydrate phosphorylation+++GO:0046838///phosphorylated carbohydrate dephosphorylation+++GO:0046959///habituation+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1904666///regulation of ubiquitin protein ligase activity+++GO:2000465///regulation of glycogen (starch) synthase activity 13854 13854 'Epn1' mRNA 1095 982 402 24.39 21.08 9.12 13.53 13.81 13.94 18.19666667 13.76 706 710 697 826.3333333 704.3333333 0.683362913 -0.222623586 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030125///clathrin vesicle coat+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0098890///extrinsic component of postsynaptic membrane GO:0005543///phospholipid binding+++GO:0008134///transcription factor binding+++GO:0008289///lipid binding+++GO:0030276///clathrin binding+++GO:0035615///clathrin adaptor activity+++GO:0044325///ion channel binding GO:0001701///in utero embryonic development+++GO:0006897///endocytosis+++GO:0007219///Notch signaling pathway+++GO:0007565///female pregnancy+++GO:0048568///embryonic organ development+++GO:0090148///membrane fission+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1905445///positive regulation of clathrin coat assembly 13855 13855 'Epn2' mRNA 2116 2138 1869 25.01 24.78 23.59 19.88 18.68 19.09 24.46 19.21666667 1912 1743 1770 2041 1808.333333 0.012604689 -0.184925893 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0030125///clathrin vesicle coat+++GO:0030128///clathrin coat of endocytic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0030276///clathrin binding GO:0001701///in utero embryonic development+++GO:0006897///endocytosis+++GO:0007219///Notch signaling pathway+++GO:0030100///regulation of endocytosis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0048568///embryonic organ development+++GO:1903671///negative regulation of sprouting angiogenesis 13857 13857 'Epor' mRNA 36 29 36 1.13 0.84 1.14 0.63 1.07 0.97 1.036666667 0.89 25 40 36 33.66666667 33.66666667 0.991392599 -0.01128103 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0004900///erythropoietin receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0003007///heart morphogenesis+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0009790///embryo development+++GO:0010976///positive regulation of neuron projection development+++GO:0016032///viral process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0038162///erythropoietin-mediated signaling pathway+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0046697///decidualization+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0061032///visceral serous pericardium development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 13858 13858 'Eps15' mRNA 1462 1436 1531 15.09 14.57 16.79 18.67 18.8 18.26 15.48333333 18.57666667 2072 2046 1978 1476.333333 2032 3.40E-08 0.446958636 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0016324///apical plasma membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030132///clathrin coat of coated pit+++GO:0030136///clathrin-coated vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0060170///ciliary membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001921///positive regulation of receptor recycling+++GO:0006895///Golgi to endosome transport+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0032456///endocytic recycling+++GO:0032880///regulation of protein localization+++GO:0042127///regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0048268///clathrin coat assembly+++GO:0098884///postsynaptic neurotransmitter receptor internalization 13859 13859 'Eps15l1' mRNA 1247 1257 1113 22.24 21.81 21.03 16.56 16.32 15.88 21.69333333 16.25333333 1095 1053 1029 1205.666667 1059 0.024065518 -0.197297814 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030132///clathrin coat of coated pit GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0016197///endosomal transport 13860 13860 'Eps8' mRNA 616 717 522 7.5 8.91 7.03 10.14 10.4 11.39 7.813333333 10.64333333 898 894 967 618.3333333 919.6666667 3.23E-07 0.566176358 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032426///stereocilium tip+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0035591///signaling adaptor activity GO:0007266///Rho protein signal transduction+++GO:0008344///adult locomotory behavior+++GO:0008360///regulation of cell shape+++GO:0010458///exit from mitosis+++GO:0016601///Rac protein signal transduction+++GO:0030832///regulation of actin filament length+++GO:0031532///actin cytoskeleton reorganization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0036336///dendritic cell migration+++GO:0048149///behavioral response to ethanol+++GO:0051016///barbed-end actin filament capping+++GO:0051017///actin filament bundle assembly+++GO:0051764///actin crosslink formation+++GO:0070358///actin polymerization-dependent cell motility+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1900029///positive regulation of ruffle assembly+++GO:1990830///cellular response to leukemia inhibitory factor 13861 13861 'Epx' mRNA 3 0 0 0.06 0 0 0 0.02 0 0.02 0.006666667 0 1 0 1 0.333333333 0.750387006 -1.467466155 05310///Asthma GO:0005615///extracellular space GO:0004601///peroxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0002215///defense response to nematode+++GO:0006952///defense response+++GO:0006979///response to oxidative stress+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042742///defense response to bacterium+++GO:0042744///hydrogen peroxide catabolic process+++GO:0072677///eosinophil migration+++GO:0098869///cellular oxidant detoxification 13863 13863 'Lcn5' mRNA 1 2 0 0.08 0.14 0 0.09 0.12 0 0.073333333 0.07 1 1 0 1 0.666666667 0.87095429 -0.565196545 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005501///retinoid binding+++GO:0036094///small molecule binding GO:0042573///retinoic acid metabolic process 13864 13864 'Nr2f6' mRNA 548 493 212 14.52 12.82 6.49 6 8.35 9.69 11.27666667 8.013333333 235 342 368 417.6666667 315 0.462390282 -0.396174533 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0048666///neuron development+++GO:0048856///anatomical structure development+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain" 13865 13865 'Nr2f1' mRNA 126 126 124 4.06 4.01 4.27 2.75 2.16 2.78 4.113333333 2.563333333 92 77 93 125.3333333 87.33333333 0.033972751 -0.534180146 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0021796///cerebral cortex regionalization+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0030900///forebrain development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA" 13866 13866 'Erbb2' mRNA 1443 1379 1530 15.42 14.49 17.35 11.08 11.27 11.74 15.75333333 11.36333333 1193 1186 1225 1450.666667 1201.333333 0.002560213 -0.286622198 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05219///Bladder cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0009925///basal plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0038143///ERBB3:ERBB2 complex+++GO:0043209///myelin sheath+++GO:0043219///lateral loop+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0001042///RNA polymerase I core binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043125///ErbB-3 class receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051879///Hsp90 protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007422///peripheral nervous system development+++GO:0007507///heart development+++GO:0007528///neuromuscular junction development+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0010001///glial cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030182///neuron differentiation+++GO:0030307///positive regulation of cell growth+++GO:0032886///regulation of microtubule-based process+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:0033674///positive regulation of kinase activity+++GO:0035556///intracellular signal transduction+++GO:0042060///wound healing+++GO:0042552///myelination+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0044849///estrous cycle+++GO:0045727///positive regulation of translation+++GO:0045785///positive regulation of cell adhesion+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046777///protein autophosphorylation+++GO:0048485///sympathetic nervous system development+++GO:0048678///response to axon injury+++GO:0048709///oligodendrocyte differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0090314///positive regulation of protein targeting to membrane 13867 13867 'Erbb3' mRNA 2118 2216 2053 18.73 19.27 19.26 12.64 11.15 11.69 19.08666667 11.82666667 1646 1418 1474 2129 1512.666667 1.06E-11 -0.505484578 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0038143///ERBB3:ERBB2 complex+++GO:0043235///receptor complex+++GO:0045211///postsynaptic membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0038131///neuregulin receptor activity+++GO:0038132///neuregulin binding+++GO:0042802///identical protein binding+++GO:0043125///ErbB-3 class receptor binding+++GO:0046982///protein heterodimerization activity GO:0003197///endocardial cushion development+++GO:0006468///protein phosphorylation+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007422///peripheral nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0009968///negative regulation of signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0014037///Schwann cell differentiation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021545///cranial nerve development+++GO:0033674///positive regulation of kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046326///positive regulation of glucose import+++GO:0051048///negative regulation of secretion+++GO:0051402///neuron apoptotic process+++GO:0055025///positive regulation of cardiac muscle tissue development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 13869 13869 'Erbb4' mRNA 644.06 650.95 543.14 5.29 5.2 4.06 0.42 0.49 0.68 4.85 0.53 76.74 101 109.78 612.7166667 95.84 1.66E-63 -2.690041467 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++05014///Amyotrophic lateral sclerosis+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0038132///neuregulin binding+++GO:0042803///protein homodimerization activity "GO:0001755///neural crest cell migration+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0007507///heart development+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021551///central nervous system morphogenesis+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0033674///positive regulation of kinase activity+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043129///surfactant homeostasis+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045165///cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046326///positive regulation of glucose import+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046777///protein autophosphorylation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060074///synapse maturation+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060749///mammary gland alveolus development+++GO:0061026///cardiac muscle tissue regeneration+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071073///positive regulation of phospholipid biosynthetic process+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072046///establishment of planar polarity involved in nephron morphogenesis+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2001223///negative regulation of neuron migration" 13870 13870 'Ercc1' mRNA 592 535 530 34.05 30.46 32.26 34.99 33.66 33.03 32.25666667 33.89333333 697 653 635 552.3333333 661.6666667 0.031927138 0.248641778 01524///Platinum drug resistance+++03420///Nucleotide excision repair+++03460///Fanconi anemia pathway "GO:0000109///nucleotide-excision repair complex+++GO:0000110///nucleotide-excision repair factor 1 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070522///ERCC4-ERCC1 complex" GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:1990599///3' overhang single-stranded DNA endodeoxyribonuclease activity+++GO:1990841///promoter-specific chromatin binding "GO:0000710///meiotic mismatch repair+++GO:0000720///pyrimidine dimer repair by nucleotide-excision repair+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006312///mitotic recombination+++GO:0006949///syncytium formation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007584///response to nutrient+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0009650///UV protection+++GO:0009744///response to sucrose+++GO:0010165///response to X-ray+++GO:0010259///multicellular organism aging+++GO:0032205///negative regulation of telomere maintenance+++GO:0035166///post-embryonic hemopoiesis+++GO:0035264///multicellular organism growth+++GO:0035902///response to immobilization stress+++GO:0036297///interstrand cross-link repair+++GO:0045190///isotype switching+++GO:0046686///response to cadmium ion+++GO:0048468///cell development+++GO:0048477///oogenesis+++GO:0048568///embryonic organ development+++GO:0051276///chromosome organization+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0061819///telomeric DNA-containing double minutes formation+++GO:0070914///UV-damage excision repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090399///replicative senescence+++GO:0090656///t-circle formation+++GO:1904431///positive regulation of t-circle formation+++GO:1905765///negative regulation of protection from non-homologous end joining at telomere" 13871 13871 'Ercc2' mRNA 809.28 772.85 674.34 12.31 11.56 10.88 8.77 7.72 8.21 11.58333333 8.233333333 663.86 570.78 599.5 752.1566667 611.38 0.004770889 -0.310035525 03022///Basal transcription factors+++03420///Nucleotide excision repair GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0070516///CAK-ERCC2 complex+++GO:0071817///MMXD complex "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003684///damaged DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0030674///protein binding, bridging+++GO:0043139///5'-3' DNA helicase activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000717///nucleotide-excision repair, DNA duplex unwinding+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007059///chromosome segregation+++GO:0007568///aging+++GO:0008283///cell proliferation+++GO:0009411///response to UV+++GO:0009650///UV protection+++GO:0009791///post-embryonic development+++GO:0021510///spinal cord development+++GO:0022405///hair cycle process+++GO:0030198///extracellular matrix organization+++GO:0030282///bone mineralization+++GO:0032289///central nervous system myelin formation+++GO:0032508///DNA duplex unwinding+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0035264///multicellular organism growth+++GO:0035315///hair cell differentiation+++GO:0040016///embryonic cleavage+++GO:0042274///ribosomal small subunit biogenesis+++GO:0043249///erythrocyte maturation+++GO:0043388///positive regulation of DNA binding+++GO:0043588///skin development+++GO:0045951///positive regulation of mitotic recombination+++GO:0048568///embryonic organ development+++GO:0048820///hair follicle maturation+++GO:0060218///hematopoietic stem cell differentiation+++GO:1901990///regulation of mitotic cell cycle phase transition" 13872 13872 'Ercc3' mRNA 435 406 445 8.99 8.39 9.84 10.3 9.65 8.9 9.073333333 9.616666667 567 516 480 428.6666667 521 0.050737118 0.266687325 03022///Basal transcription factors+++03420///Nucleotide excision repair GO:0000112///nucleotide-excision repair factor 3 complex+++GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0097550///transcriptional preinitiation complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0047485///protein N-terminus binding+++GO:1990841///promoter-specific chromatin binding "GO:0000717///nucleotide-excision repair, DNA duplex unwinding+++GO:0001666///response to hypoxia+++GO:0006265///DNA topological change+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0008104///protein localization+++GO:0009411///response to UV+++GO:0009650///UV protection+++GO:0032508///DNA duplex unwinding+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0035315///hair cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0048568///embryonic organ development+++GO:1901990///regulation of mitotic cell cycle phase transition" 13874 13874 'Ereg' mRNA 0 1 0 0 0.01 0 0.01 0.05 0.05 0.003333333 0.036666667 1 4 4 0.333333333 3 0.203424431 3.063958305 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04151///PI3K-Akt signaling pathway+++05210///Colorectal cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005154///epidermal growth factor receptor binding+++GO:0008083///growth factor activity "GO:0001525///angiogenesis+++GO:0001550///ovarian cumulus expansion+++GO:0001556///oocyte maturation+++GO:0001819///positive regulation of cytokine production+++GO:0007143///female meiotic nuclear division+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009299///mRNA transcription+++GO:0009653///anatomical structure morphogenesis+++GO:0009887///animal organ morphogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0030728///ovulation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042327///positive regulation of phosphorylation+++GO:0042700///luteinizing hormone signaling pathway+++GO:0043434///response to peptide hormone+++GO:0043616///keratinocyte proliferation+++GO:0045089///positive regulation of innate immune response+++GO:0045740///positive regulation of DNA replication+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048160///primary follicle stage+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:0051781///positive regulation of cell division" 13875 13875 'Erf' mRNA 128 95 81 1.91 1.39 1.34 1.84 1.81 1.88 1.546666667 1.843333333 138 130 135 101.3333333 134.3333333 0.129934677 0.399283442 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010668///ectodermal cell differentiation+++GO:0030154///cell differentiation+++GO:0060707///trophoblast giant cell differentiation+++GO:0060710///chorio-allantoic fusion" 13876 13876 'Erg' mRNA 64 39 29 1.1 0.66 0.54 0.87 0.86 0.97 0.766666667 0.9 58 56 63 44 59 0.331709576 0.41989636 05202///Transcriptional misregulation in cancer+++05215///Prostate cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003197///endocardial cushion development+++GO:0003199///endocardial cushion to mesenchymal transition involved in heart valve formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000504///positive regulation of blood vessel remodeling" 13877 13877 'Erh' mRNA 1554 1369 1490 98.26 85.72 100.79 154.88 173.23 153.3 94.92333333 160.47 2807.44 3059 2677.99 1471 2848.143333 6.27E-28 0.940342207 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0034709///methylosome GO:0008327///methyl-CpG binding GO:0001649///osteoblast differentiation+++GO:0007049///cell cycle 13885 13885 'Esd' mRNA 1448 1505 1485 55.4 55.17 59.46 100.91 103.95 98.53 56.67666667 101.13 3070.64 3010 2907 1479.333333 2995.88 1.00E-47 1.005347202 01200///Carbon metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle "GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0018738///S-formylglutathione hydrolase activity+++GO:0042802///identical protein binding+++GO:0052689///carboxylic ester hydrolase activity" GO:0046294///formaldehyde catabolic process 13897 13897 'Ces1e' mRNA 0 5 1 0 0.14 0.03 0.02 0 0 0.056666667 0.006666667 1 0 0 2 0.333333333 0.431103393 -2.46786122 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0080030///methyl indole-3-acetate esterase activity" GO:0006695///cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0016042///lipid catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0042572///retinol metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0051791///medium-chain fatty acid metabolic process+++GO:0070857///regulation of bile acid biosynthetic process+++GO:0071397///cellular response to cholesterol+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090205///positive regulation of cholesterol metabolic process+++GO:0120188///regulation of bile acid secretion 13929 13929 'Amz2' mRNA 738 838 775 13.99 15.84 15.62 11.29 11.89 13.09 15.15 12.09 685 704 769 783.6666667 719.3333333 0.270704779 -0.134756266 GO:0005575///cellular_component GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 13972 13972 'Gnb1l' mRNA 428 452 420 6.34 6.49 6.57 3.8 3.49 4.3 6.466666667 3.863333333 293 265 319 433.3333333 292.3333333 2.90E-05 -0.579503872 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0035176///social behavior 13982 13982 'Esr1' mRNA 12 23 24 0.1 0.19 0.22 0.75 0.34 0.61 0.17 0.566666667 77 45 76 19.66666667 66 6.92E-05 1.726693512 01522///Endocrine resistance+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04961///Endocrine and other factor-regulated calcium reabsorption+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0032991///protein-containing complex+++GO:0035327///transcriptionally active chromatin+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0097550///transcriptional preinitiation complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001093///TFIIB-class transcription factor binding+++GO:0001222///transcription corepressor binding+++GO:0001223///transcription coactivator binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0017025///TBP-class protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030284///estrogen receptor activity+++GO:0030331///estrogen receptor binding+++GO:0031798///type 1 metabotropic glutamate receptor binding+++GO:0034056///estrogen response element binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001547///antral ovarian follicle growth+++GO:0002064///epithelial cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008209///androgen metabolic process+++GO:0008584///male gonad development+++GO:0010629///negative regulation of gene expression+++GO:0010863///positive regulation of phospholipase C activity+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0032355///response to estradiol+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043523///regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046325///negative regulation of glucose import+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048863///stem cell differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060011///Sertoli cell proliferation+++GO:0060065///uterus development+++GO:0060068///vagina development+++GO:0060523///prostate epithelial cord elongation+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0060687///regulation of branching involved in prostate gland morphogenesis+++GO:0060745///mammary gland branching involved in pregnancy+++GO:0060749///mammary gland alveolus development+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071168///protein localization to chromatin+++GO:0071391///cellular response to estrogen stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0090209///negative regulation of triglyceride metabolic process+++GO:1901215///negative regulation of neuron death+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA" 13983 13983 'Esr2' mRNA 118 139 138 1.95 2.25 2.4 0.29 0.26 0.43 2.2 0.326666667 20 18 29 131.6666667 22.33333333 5.14E-16 -2.57325256 01522///Endocrine resistance+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04929///GnRH secretion+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0032993///protein-DNA complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0030284///estrogen receptor activity+++GO:0034056///estrogen response element binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0097159///organic cyclic compound binding+++GO:0099130///estrogen binding+++GO:1901363///heterocyclic compound binding+++GO:1903924///estradiol binding+++GO:1990239///steroid hormone binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0001662///behavioral fear response+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007611///learning or memory+++GO:0008285///negative regulation of cell proliferation+++GO:0008628///hormone-mediated apoptotic signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0033574///response to testosterone+++GO:0042127///regulation of cell proliferation+++GO:0042311///vasodilation+++GO:0043065///positive regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0044849///estrous cycle+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048521///negative regulation of behavior+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060011///Sertoli cell proliferation+++GO:0060065///uterus development+++GO:0060068///vagina development+++GO:0060548///negative regulation of cell death+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071392///cellular response to estradiol stimulus+++GO:1901215///negative regulation of neuron death+++GO:2000252///negative regulation of feeding behavior+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 13990 13990 'Smarcad1' mRNA 702.11 648.96 575.63 12.05 11.17 9.89 12.47 13.3 14.25 11.03666667 13.34 754.99 685.12 685.46 642.2333333 708.5233333 0.279643006 0.131854403 04550///Signaling pathways regulating pluripotency of stem cells GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0035861///site of double-strand break+++GO:0043596///nuclear replication fork GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0043130///ubiquitin binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0000018///regulation of DNA recombination+++GO:0000729///DNA double-strand break processing+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032508///DNA duplex unwinding+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0051304///chromosome separation+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation 13992 13992 'Khdrbs3' mRNA 102 103 105 3.04 3.04 3.35 2.81 2.18 1.96 3.143333333 2.316666667 108 82 72 103.3333333 87.33333333 0.406558999 -0.258244268 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0033120///positive regulation of RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome" 13998 13998 'Fgd6' mRNA 448 464 401 3.09 3.17 3.3 4.29 3.87 4.21 3.186666667 4.123333333 660 559 626 437.6666667 615 4.39E-05 0.47992904 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0043087///regulation of GTPase activity 13999 13999 'Gm14288' mRNA 86.38 117.19 122.68 19.19 26.18 28.95 24 34.2 29.93 24.77333333 29.37666667 122.35 168.78 146.45 108.75 145.86 0.130765547 0.411136657 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 14000 14000 'Drosha' mRNA 1239.06 1332.53 1018 14.52 15.37 12.65 7.03 6.83 6.45 14.18 6.77 690.07 654.99 613 1196.53 652.6866667 6.44E-19 -0.88248338 03008///Ribosome biogenesis in eukaryotes+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0070877///microprocessor complex GO:0001530///lipopolysaccharide binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004525///ribonuclease III activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0042803///protein homodimerization activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding+++GO:0070878///primary miRNA binding "GO:0006396///RNA processing+++GO:0010468///regulation of gene expression+++GO:0010586///miRNA metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0016075///rRNA catabolic process+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031053///primary miRNA processing+++GO:0031054///pre-miRNA processing+++GO:0042254///ribosome biogenesis+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0050727///regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:2000628///regulation of miRNA metabolic process" 14004 14004 'Chchd2' mRNA 10328.24 10663.3 10048.33 743.72 760.02 767.79 706.52 747.57 702.69 757.1766667 718.9266667 11241.77 11589.6 10801.16 10346.62333 11210.84333 0.081572574 0.104520866 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding GO:0007005///mitochondrion organization+++GO:0034599///cellular response to oxidative stress+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1900037///regulation of cellular response to hypoxia+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport 14007 14007 'Celf2' mRNA 2562.78 2679.62 2124.11 15.1 16.51 12.9 16.94 16 16.48 14.83666667 16.47333333 2808.77 2527.47 2684.6 2455.503333 2673.613333 0.167383081 0.114374191 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090543///Flemming body+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0036002///pre-mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0016441///posttranscriptional gene silencing" 14009 14009 'Etv1' mRNA 1577.55 1669.94 1658.79 18.4 18.99 20.53 15.09 15.43 15.3 19.30666667 15.27333333 1493.93 1476 1476.28 1635.426667 1482.07 0.073858994 -0.154625892 05202///Transcriptional misregulation in cancer GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007411///axon guidance+++GO:0007517///muscle organ development+++GO:0007638///mechanosensory behavior+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048935///peripheral nervous system neuron development" 14011 14011 'Etv6' mRNA 756 741 704 7.22 7.18 7.09 8.18 7.86 8.16 7.163333333 8.066666667 984 922 960 733.6666667 955.3333333 7.71E-05 0.369344553 04013///MAPK signaling pathway - fly+++04320///Dorso-ventral axis formation+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007296///vitellogenesis+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071425///hematopoietic stem cell proliferation+++GO:0097152///mesenchymal cell apoptotic process" 14012 14012 'Mpzl2' mRNA 6209 6509 6295 105.84 109.07 113.89 94.13 91.05 88.36 109.6 91.18 6354 6007 5777 6337.666667 6046 0.234615826 -0.080818974 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0033077///T cell differentiation in thymus+++GO:0098609///cell-cell adhesion 14013 14013 'Mecom' mRNA 72 70 69 1.05 0.77 0.84 0.55 0.7 0.69 0.886666667 0.646666667 43 69 62 70.33333333 58 0.459060573 -0.286300487 00310///Lysine degradation+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++05220///Chronic myeloid leukemia GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)" "GO:0001701///in utero embryonic development+++GO:0001780///neutrophil homeostasis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007275///multicellular organism development+++GO:0009617///response to bacterium+++GO:0009791///post-embryonic development+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0032259///methylation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0043069///negative regulation of programmed cell death+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0051567///histone H3-K9 methylation+++GO:0051726///regulation of cell cycle+++GO:0060039///pericardium development+++GO:0070828///heterochromatin organization+++GO:0071425///hematopoietic stem cell proliferation+++GO:0072197///ureter morphogenesis+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0098727///maintenance of cell number" 14017 14017 'Evi2a' mRNA 93.29 102 112.26 3.14 3.61 4.36 28.08 29.64 30.3 3.703333333 29.34 855.53 867.19 882.2 102.5166667 868.3066667 2.15E-109 3.071547729 GO:0016020///membrane+++GO:0016021///integral component of membrane 14020 14020 'Evi5' mRNA 1321.19 1443.01 1227.49 9.58 9.94 8.82 6.07 5.21 5.85 9.446666667 5.71 961.02 793 898 1330.563333 884.0066667 4.17E-11 -0.600613625 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding "GO:0006886///intracellular protein transport+++GO:0007049///cell cycle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0051301///cell division+++GO:0090630///activation of GTPase activity" 14025 14025 'Bcl11a' mRNA 202 208 167 3.75 3.74 3.77 1.53 1.18 1.11 3.753333333 1.273333333 105 68 68 192.3333333 80.33333333 4.75E-08 -1.271009189 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001067///regulatory region nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0016925///protein sumoylation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0048671///negative regulation of collateral sprouting+++GO:0048672///positive regulation of collateral sprouting+++GO:0050773///regulation of dendrite development+++GO:1903860///negative regulation of dendrite extension+++GO:1904800///negative regulation of neuron remodeling+++GO:1905232///cellular response to L-glutamate+++GO:2000171///negative regulation of dendrite development+++GO:2000173///negative regulation of branching morphogenesis of a nerve 14026 14026 'Evl' mRNA 1794.52 1747.86 991.32 54.8 52.5 32.29 11.76 11.16 11.67 46.53 11.53 439.17 407.99 421.7 1511.233333 422.9533333 3.87E-35 -1.838641495 04015///Rap1 signaling pathway+++04361///Axon regeneration GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0045335///phagocytic vesicle GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0017124///SH3 domain binding GO:0007411///axon guidance+++GO:0008154///actin polymerization or depolymerization+++GO:0010633///negative regulation of epithelial cell migration+++GO:0030048///actin filament-based movement+++GO:0030168///platelet activation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0045010///actin nucleation+++GO:0051016///barbed-end actin filament capping+++GO:0051289///protein homotetramerization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0071346///cellular response to interferon-gamma+++GO:1900028///negative regulation of ruffle assembly 14027 14027 'Evpl' mRNA 90 79 70 0.74 0.63 0.61 0.97 0.67 0.82 0.66 0.82 135 91 111 79.66666667 112.3333333 0.088974142 0.483626161 GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0045111///intermediate filament cytoskeleton GO:0005198///structural molecule activity+++GO:0019215///intermediate filament binding GO:0008544///epidermis development+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization 14030 14030 'Ewsr1' mRNA 9602.83 9774 8611 200.03 200.07 191.29 162.7 164.08 158.19 197.13 161.6566667 8798.81 8666.86 8332.36 9329.276667 8599.343333 0.019452506 -0.127414622 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0015030///Cajal body+++GO:0016020///membrane GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated" 14038 14038 'Wfdc18' mRNA 33 33 27 4.88 4.87 4.24 293.44 328.97 317.87 4.663333333 313.4266667 2258 2458 2355 31 2357 6.34E-289 6.239305998 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 14042 14042 'Ext1' mRNA 265 269 221 4.16 4.16 3.68 5.15 4.47 5.14 4 4.92 377 320 365 251.6666667 354 0.001528548 0.482558593 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0045202///synapse "GO:0008375///acetylglucosaminyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050508///glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0050509///N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity" "GO:0000902///cell morphogenesis+++GO:0001503///ossification+++GO:0001958///endochondral ossification+++GO:0001974///blood vessel remodeling+++GO:0002062///chondrocyte differentiation+++GO:0002067///glandular epithelial cell differentiation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002524///hypersensitivity+++GO:0003128///heart field specification+++GO:0003415///chondrocyte hypertrophy+++GO:0003416///endochondral bone growth+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006486///protein glycosylation+++GO:0007033///vacuole organization+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007369///gastrulation+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007492///endoderm development+++GO:0007498///mesoderm development+++GO:0008217///regulation of blood pressure+++GO:0008283///cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009615///response to virus+++GO:0009642///response to light intensity+++GO:0010467///gene expression+++GO:0014033///neural crest cell differentiation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0016043///cellular component organization+++GO:0017145///stem cell division+++GO:0019882///antigen processing and presentation+++GO:0021554///optic nerve development+++GO:0021772///olfactory bulb development+++GO:0022405///hair cycle process+++GO:0030163///protein catabolic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0030202///heparin metabolic process+++GO:0030204///chondroitin sulfate metabolic process+++GO:0030210///heparin biosynthetic process+++GO:0030509///BMP signaling pathway+++GO:0031069///hair follicle morphogenesis+++GO:0031175///neuron projection development+++GO:0032602///chemokine production+++GO:0032836///glomerular basement membrane development+++GO:0033627///cell adhesion mediated by integrin+++GO:0033692///cellular polysaccharide biosynthetic process+++GO:0035176///social behavior+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035264///multicellular organism growth+++GO:0035988///chondrocyte proliferation+++GO:0036022///limb joint morphogenesis+++GO:0036336///dendritic cell migration+++GO:0036339///lymphocyte adhesion to endothelial cell of high endothelial venule+++GO:0042044///fluid transport+++GO:0042060///wound healing+++GO:0042311///vasodilation+++GO:0042596///fear response+++GO:0043931///ossification involved in bone maturation+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0045453///bone resorption+++GO:0048598///embryonic morphogenesis+++GO:0048733///sebaceous gland development+++GO:0050891///multicellular organismal water homeostasis+++GO:0050901///leukocyte tethering or rolling+++GO:0051923///sulfation+++GO:0055078///sodium ion homeostasis+++GO:0060047///heart contraction+++GO:0060070///canonical Wnt signaling pathway+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060349///bone morphogenesis+++GO:0060350///endochondral bone morphogenesis+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0060429///epithelium development+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060485///mesenchyme development+++GO:0060506///smoothened signaling pathway involved in lung development+++GO:0060560///developmental growth involved in morphogenesis+++GO:0060792///sweat gland development+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0061744///motor behavior+++GO:0061974///perichondral bone morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:0070593///dendrite self-avoidance+++GO:0070848///response to growth factor+++GO:0071503///response to heparin+++GO:0071625///vocalization behavior+++GO:0071711///basement membrane organization+++GO:0071773///cellular response to BMP stimulus+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0072498///embryonic skeletal joint development+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:0097241///hematopoietic stem cell migration to bone marrow+++GO:0098586///cellular response to virus+++GO:0098868///bone growth+++GO:0120193///tight junction organization+++GO:1901706///mesenchymal cell differentiation involved in bone development+++GO:1904888///cranial skeletal system development+++GO:1990823///response to leukemia inhibitory factor" 14043 14043 'Ext2' mRNA 2090 2434 2182 39.91 45.78 44.25 46.93 48.35 46.04 43.31333333 47.10666667 2833 2844 2692 2235.333333 2789.666667 4.55E-05 0.308416248 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043541///UDP-N-acetylglucosamine transferase complex "GO:0005515///protein binding+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042328///heparan sulfate N-acetylglucosaminyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050508///glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0050509///N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity" "GO:0001503///ossification+++GO:0001707///mesoderm formation+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0008217///regulation of blood pressure+++GO:0010467///gene expression+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0030154///cell differentiation+++GO:0030210///heparin biosynthetic process+++GO:0033692///cellular polysaccharide biosynthetic process+++GO:0042044///fluid transport+++GO:0042311///vasodilation+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0050891///multicellular organismal water homeostasis+++GO:0051923///sulfation+++GO:0055078///sodium ion homeostasis+++GO:0060047///heart contraction+++GO:0060350///endochondral bone morphogenesis" 140474 140474 'Muc4' mRNA 1 2 0 0 0.01 0 0.01 0.03 0.01 0.003333333 0.016666667 3 7 3 1 4.333333333 0.248696969 2.133806546 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0005176///ErbB-2 class receptor binding+++GO:0044877///protein-containing complex binding GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002853///negative regulation of T cell mediated cytotoxicity directed against tumor cell target+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0010469///regulation of signaling receptor activity+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0043066///negative regulation of apoptotic process 140475 140475 'Bsnd' mRNA 1887 1960 2002 38.45 39.31 43.27 14.51 13.08 13.28 40.34333333 13.62333333 819 721 726 1949.666667 755.3333333 2.17E-57 -1.382583444 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0032991///protein-containing complex GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0017081///chloride channel regulator activity GO:0006821///chloride transport+++GO:0006873///cellular ion homeostasis+++GO:0007605///sensory perception of sound+++GO:0030007///cellular potassium ion homeostasis+++GO:0030644///cellular chloride ion homeostasis 140476 140476 'Strc' mRNA 1066 995 736 9.77 8.97 7.19 0.55 0.66 0.57 8.643333333 0.593333333 70 81 70 932.3333333 73.66666667 2.58E-115 -3.666268158 GO:0005929///cilium+++GO:0009986///cell surface+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0060091///kinocilium GO:0003674///molecular_function GO:0007160///cell-matrix adhesion+++GO:0007605///sensory perception of sound+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060088///auditory receptor cell stereocilium organization 140477 140477 'Dmbx1' mRNA 21 37 29 0.28 0.49 0.39 0.14 0.22 0.11 0.386666667 0.156666667 13 18 9 29 13.33333333 0.059111278 -1.130066436 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0008343///adult feeding behavior+++GO:0008344///adult locomotory behavior+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048589///developmental growth" 14048 14048 'Eya1' mRNA 5977 6097 5853 76.64 77.3 79.29 28.02 25.66 27.72 77.74333333 27.13333333 2520 2238 2354 5975.666667 2370.666667 5.27E-114 -1.346598111 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex GO:0003723///RNA binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000132///establishment of mitotic spindle orientation+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007501///mesodermal cell fate specification+++GO:0009887///animal organ morphogenesis+++GO:0010212///response to ionizing radiation+++GO:0014706///striated muscle tissue development+++GO:0016576///histone dephosphorylation+++GO:0016925///protein sumoylation+++GO:0030154///cell differentiation+++GO:0034613///cellular protein localization+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035909///aorta morphogenesis+++GO:0042471///ear morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042473///outer ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0045165///cell fate commitment+++GO:0045664///regulation of neuron differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048665///neuron fate specification+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048752///semicircular canal morphogenesis+++GO:0048856///anatomical structure development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060037///pharyngeal system development+++GO:0060487///lung epithelial cell differentiation+++GO:0071599///otic vesicle development+++GO:0071600///otic vesicle morphogenesis+++GO:0072513///positive regulation of secondary heart field cardioblast proliferation+++GO:0090103///cochlea morphogenesis+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 140481 140481 'Man2a2' mRNA 2691.51 2650.99 2531.51 21.73 21.09 21.7 16.28 16.1 15.85 21.50666667 16.07666667 2318.09 2241.07 2190.13 2624.67 2249.763333 4.51E-04 -0.233669251 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0004559///alpha-mannosidase activity+++GO:0004572///mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity+++GO:0015923///mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0006517///protein deglycosylation+++GO:0008152///metabolic process 140482 140482 'Zfp358' mRNA 768 844 274 21.87 23.68 8.28 7.06 9.16 10.21 17.94333333 8.81 285 361 399 628.6666667 348.3333333 0.117727176 -0.838255457 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0021915///neural tube development+++GO:0035115///embryonic forelimb morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II 140483 140483 'Hnmt' mRNA 245 234 236 8.68 8.11 8.87 9.39 9.39 9.31 8.553333333 9.363333333 305 296 291 238.3333333 297.3333333 0.060607737 0.306812163 00340///Histidine metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0043005///neuron projection GO:0008168///methyltransferase activity+++GO:0008170///N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046539///histamine N-methyltransferase activity GO:0001505///regulation of neurotransmitter levels+++GO:0001692///histamine metabolic process+++GO:0001695///histamine catabolic process+++GO:0002347///response to tumor cell+++GO:0006972///hyperosmotic response+++GO:0007420///brain development+++GO:0014075///response to amine+++GO:0032259///methylation+++GO:0035902///response to immobilization stress+++GO:0042220///response to cocaine+++GO:0051384///response to glucocorticoid+++GO:0070555///response to interleukin-1 140484 140484 'Pofut1' mRNA 367 327 313 3.41 3.01 3.1 3.71 2.97 3.46 3.173333333 3.38 458 356 409 335.6666667 407.6666667 0.080775617 0.267856573 00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0016020///membrane "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046922///peptide-O-fucosyltransferase activity" GO:0001525///angiogenesis+++GO:0001756///somitogenesis+++GO:0005975///carbohydrate metabolic process+++GO:0006004///fucose metabolic process+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0007219///Notch signaling pathway+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0008593///regulation of Notch signaling pathway+++GO:0036066///protein O-linked fucosylation 140486 140486 'Igf2bp1' mRNA 39 19 16 0.24 0.12 0.11 0.1 0.14 0.12 0.156666667 0.12 19 25 21 24.66666667 21.66666667 0.803519186 -0.188358816 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003692///left-handed Z-DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006403///RNA localization+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0012501///programmed cell death+++GO:0017148///negative regulation of translation+++GO:0022013///pallium cell proliferation in forebrain+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051028///mRNA transport+++GO:0051252///regulation of RNA metabolic process+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060545///positive regulation of necroptotic process+++GO:0070269///pyroptosis+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0097150///neuronal stem cell population maintenance+++GO:0140059///dendrite arborization+++GO:2000659///regulation of interleukin-1-mediated signaling pathway 140488 140488 'Igf2bp3' mRNA 117 89 87 1.5 1.12 1.15 0.73 0.76 0.72 1.256666667 0.736666667 69 70 66 97.66666667 68.33333333 0.075354671 -0.524890934 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0048027///mRNA 5'-UTR binding GO:0006417///regulation of translation+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0051028///mRNA transport+++GO:0051252///regulation of RNA metabolic process 140489 140489 'Bhlhe23' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030182///neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046548///retinal rod cell development+++GO:0046671///negative regulation of retinal cell programmed cell death+++GO:0048050///post-embryonic eye morphogenesis+++GO:0048468///cell development" 14049 14049 'Eya2' mRNA 120 135 137 2.78 3.05 3.4 3.03 3.11 3.43 3.076666667 3.19 148 140 160 130.6666667 149.3333333 0.488687341 0.179092088 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0014706///striated muscle tissue development+++GO:0016576///histone dephosphorylation+++GO:0030154///cell differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045739///positive regulation of DNA repair+++GO:0048856///anatomical structure development+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 140492 140492 'Kcnn2' mRNA 570 585 500 11.68 12.44 11.54 2.79 2.39 2.26 11.88666667 2.48 147 119 121 551.6666667 129 2.13E-47 -2.107014575 04726///Serotonergic synapse+++04911///Insulin secretion+++04929///GnRH secretion+++04976///Bile secretion GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine GO:0005216///ion channel activity+++GO:0005242///inward rectifier potassium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0016286///small conductance calcium-activated potassium channel activity+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0051393///alpha-actinin binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0043268///positive regulation of potassium ion transport+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0071805///potassium ion transmembrane transport+++GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:1901379///regulation of potassium ion transmembrane transport 140493 140493 'Kcnn3' mRNA 68 52 70 0.47 0.35 0.51 0.05 0.18 0.19 0.443333333 0.14 9 30 30 63.33333333 23 0.001472721 -1.470962943 04911///Insulin secretion+++04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030175///filopodium+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body GO:0005242///inward rectifier potassium channel activity+++GO:0005516///calmodulin binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0016286///small conductance calcium-activated potassium channel activity+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport 140494 140494 'Atp6v0a4' mRNA 6.26 6.21 12.55 0.1 0.1 0.22 0.24 0.33 0.5 0.14 0.356666667 16.46 22.64 33.29 8.34 24.13 0.028703077 1.543611768 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0031526///brush border membrane+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0045177///apical part of cell" "GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0001503///ossification+++GO:0006811///ion transport+++GO:0006885///regulation of pH+++GO:0007035///vacuolar acidification+++GO:0007588///excretion+++GO:0007605///sensory perception of sound+++GO:1902600///proton transmembrane transport 140497 140497 'Cd300c2' mRNA 71.78 75 49 3.91 4.04 2.83 58.65 61.9 58.69 3.593333333 59.74666667 1234.85 1270.8 1194.66 65.26 1233.436667 3.41E-189 4.237350825 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0008150///biological_process 140498 140498 'Rxfp2' mRNA 24 23 40 0.36 0.34 0.65 0.03 0.07 0.07 0.45 0.056666667 2 5 6 29 4.333333333 1.23E-04 -2.764392218 04080///Neuroactive ligand-receptor interaction+++04926///Relaxin signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016500///protein-hormone receptor activity+++GO:0017046///peptide hormone binding GO:0001556///oocyte maturation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009755///hormone-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043950///positive regulation of cAMP-mediated signaling 140499 140499 'Ube2j2' mRNA 512 551 276 8.16 8.59 4.79 6 6.62 6.4 7.18 6.34 423 456.36 437 446.3333333 438.7866667 0.928420292 -0.022431676 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006986///response to unfolded protein+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway 14050 14050 'Eya3' mRNA 231 219 198 5.2 4.72 3.71 5.51 5.9 6.83 4.543333333 6.08 398 400 445 216 414.3333333 1.34E-10 0.930197284 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0003682///chromatin binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0010212///response to ionizing radiation+++GO:0016576///histone dephosphorylation+++GO:0030154///cell differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045739///positive regulation of DNA repair+++GO:0048856///anatomical structure development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 140500 140500 'Acap3' mRNA 515 570 341 6.93 7.57 4.92 3.95 4.34 4.49 6.473333333 4.26 331 366 359 475.3333333 352 0.01009346 -0.434409508 04144///Endocytosis GO:0030426///growth cone GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0001764///neuron migration+++GO:0010975///regulation of neuron projection development+++GO:0050790///regulation of catalytic activity 14051 14051 'Eya4' mRNA 1462 1565 1345 14.34 15.12 14.09 4.53 3.96 3.75 14.51666667 4.08 525 454 422 1457.333333 467 4.57E-66 -1.652729795 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0016576///histone dephosphorylation+++GO:0030154///cell differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042474///middle ear morphogenesis+++GO:0045739///positive regulation of DNA repair+++GO:0048839///inner ear development+++GO:0048856///anatomical structure development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 140546 140546 'Eri3' mRNA 1536 1460 1109 68.16 65.05 56.18 47.57 49.96 52.2 63.13 49.91 1133 1177 1252 1368.333333 1187.333333 0.058089088 -0.209902112 GO:0005886///plasma membrane GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000738///DNA catabolic process, exonucleolytic" 14055 14055 'Ezh1' mRNA 1622 1721 1711 20.75 21.66 23.23 15.38 14.09 14.19 21.88 14.55333333 1383 1238 1236 1684.666667 1285.666667 1.50E-06 -0.403858428 00310///Lysine degradation "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035098///ESC/E(Z) complex" GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0031493///nucleosomal histone binding+++GO:0046976///histone methyltransferase activity (H3-K27 specific) GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006348///chromatin silencing at telomere+++GO:0021766///hippocampus development+++GO:0031507///heterochromatin assembly+++GO:0031509///telomeric heterochromatin assembly+++GO:0032259///methylation+++GO:0036333///hepatocyte homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070734///histone H3-K27 methylation+++GO:0097421///liver regeneration+++GO:0098532///histone H3-K27 trimethylation+++GO:1904772///response to tetrachloromethane 140557 140557 'Smc1b' mRNA 3 3 0 0.04 0.04 0 0.01 0.05 0.01 0.026666667 0.023333333 1 4 1 2 2 0.997429919 0.02893573 04110///Cell cycle+++04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0030893///meiotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0007049///cell cycle+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0051276///chromosome organization+++GO:0051321///meiotic cell cycle 140559 140559 'Igsf8' mRNA 1986 2090 1637 48.93 50.71 42.79 60.72 57.3 57.5 47.47666667 58.50666667 2834 2611 2598 1904.333333 2681 1.47E-10 0.485348064 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0005515///protein binding GO:2000145///regulation of cell motility 14056 14056 'Ezh2' mRNA 142 144 83 2.93 2.93 1.81 4.06 4.02 4 2.556666667 4.026666667 221 217 213 123 217 1.88E-04 0.816627992 00310///Lysine degradation+++05206///MicroRNAs in cancer "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0035098///ESC/E(Z) complex+++GO:0045120///pronucleus+++GO:0045202///synapse" GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0031490///chromatin DNA binding+++GO:0042054///histone methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0043565///sequence-specific DNA binding+++GO:0046976///histone methyltransferase activity (H3-K27 specific)+++GO:0070878///primary miRNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001932///regulation of protein phosphorylation+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006348///chromatin silencing at telomere+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0014013///regulation of gliogenesis+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0016571///histone methylation+++GO:0021695///cerebellar cortex development+++GO:0021766///hippocampus development+++GO:0030183///B cell differentiation+++GO:0031509///telomeric heterochromatin assembly+++GO:0032259///methylation+++GO:0032355///response to estradiol+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0034968///histone lysine methylation+++GO:0035984///cellular response to trichostatin A+++GO:0036333///hepatocyte homeostasis+++GO:0042127///regulation of cell proliferation+++GO:0042752///regulation of circadian rhythm+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045605///negative regulation of epidermal cell differentiation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0048468///cell development+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis+++GO:0051154///negative regulation of striated muscle cell differentiation+++GO:0051932///synaptic transmission, GABAergic+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070314///G1 to G0 transition+++GO:0070734///histone H3-K27 methylation+++GO:0071168///protein localization to chromatin+++GO:0071707///immunoglobulin heavy chain V-D-J recombination+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0097421///liver regeneration+++GO:0098532///histone H3-K27 trimethylation+++GO:1900006///positive regulation of dendrite development+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:1904772///response to tetrachloromethane+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 14057 14057 'Sfxn1' mRNA 924 954 952 18.05 18.24 19.71 23.55 24.53 24.43 18.66666667 24.17 1387 1413 1389 943.3333333 1396.333333 9.47E-11 0.55347695 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0015075///ion transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0022889///serine transmembrane transporter activity+++GO:0042945///D-serine transmembrane transporter activity GO:0006730///one-carbon metabolic process+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006865///amino acid transport+++GO:0015825///L-serine transport+++GO:0030218///erythrocyte differentiation+++GO:0034220///ion transmembrane transport+++GO:0042942///D-serine transport+++GO:0055085///transmembrane transport+++GO:1990542///mitochondrial transmembrane transport 140570 140570 'Plxnb2' mRNA 4096 4129 4219 33.73 33.38 36.78 40.04 37.53 37.47 34.63 38.34666667 5583 5111 5058 4148 5250.666667 7.14E-07 0.325961346 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity GO:0001843///neural tube closure+++GO:0001932///regulation of protein phosphorylation+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007405///neuroblast proliferation+++GO:0007420///brain development+++GO:0008360///regulation of cell shape+++GO:0010976///positive regulation of neuron projection development+++GO:0030334///regulation of cell migration+++GO:0043087///regulation of GTPase activity+++GO:0045727///positive regulation of translation+++GO:0050772///positive regulation of axonogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1904861///excitatory synapse assembly+++GO:2001222///regulation of neuron migration 140571 140571 'Plxnb3' mRNA 998 1004 854 8.78 8.69 7.97 3.69 3.69 3.28 8.48 3.553333333 482 471 415 952 456 9.12E-25 -1.071216511 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity+++GO:0019904///protein domain specific binding+++GO:0051022///Rho GDP-dissociation inhibitor binding+++GO:0098632///cell-cell adhesion mediator activity GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008360///regulation of cell shape+++GO:0010593///negative regulation of lamellipodium assembly+++GO:0010976///positive regulation of neuron projection development+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0034260///negative regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0050772///positive regulation of axonogenesis+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 140577 140577 'Ankrd6' mRNA 2486 2717 2430 29.33 31.41 30.35 7.17 6.78 7.05 30.36333333 7 698 637 662 2544.333333 665.6666667 2.06E-143 -1.945715135 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding "GO:0046330///positive regulation of JNK cascade+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway" 140579 140579 'Elmo2' mRNA 1911 2124 2017 28.18 31.04 31.65 25.14 26.71 25.23 30.29 25.69333333 1991 2057 1927 2017.333333 1991.666667 0.777800574 -0.030398334 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0017124///SH3 domain binding+++GO:0030971///receptor tyrosine kinase binding GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0016477///cell migration+++GO:0048870///cell motility+++GO:0060326///cell chemotaxis+++GO:0098609///cell-cell adhesion 14058 14058 'F10' mRNA 22 15 12 0.47 0.31 0.28 9.99 9.63 8.61 0.353333333 9.41 558 524 464.94 16.33333333 515.6466667 1.85E-84 4.969571311 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0051897///positive regulation of protein kinase B signaling 140580 140580 'Elmo1' mRNA 1899 2178 2063 27.78 31.4 32.09 14.17 12.77 14.16 30.42333333 13.7 1105 978 1071 2046.666667 1051.333333 1.14E-30 -0.974392356 04062///Chemokine signaling pathway+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032045///guanyl-nucleotide exchange factor complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding "GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0006915///apoptotic process+++GO:0007015///actin filament organization+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0030029///actin filament-based process+++GO:0030036///actin cytoskeleton organization+++GO:0048870///cell motility+++GO:0050790///regulation of catalytic activity" 14061 14061 'F2' mRNA 4 2 9 0.11 0.05 0.27 0 0.12 0 0.143333333 0.04 0 5 0 5 1.666666667 0.388089417 -1.608600212 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0001530///lipopolysaccharide binding+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070053///thrombospondin receptor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030168///platelet activation+++GO:0030194///positive regulation of blood coagulation+++GO:0030307///positive regulation of cell growth+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0042730///fibrinolysis+++GO:0045861///negative regulation of proteolysis+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051838///cytolysis by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0090218///positive regulation of lipid kinase activity+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process 14062 14062 'F2r' mRNA 2314 2347 2422 37.81 37.73 41.98 16.46 17.33 17.02 39.17333333 16.93666667 1159 1192 1161 2361 1170.666667 8.33E-39 -1.025293995 04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04610///Complement and coagulation cascades+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031094///platelet dense tubular network+++GO:0031594///neuromuscular junction+++GO:0045211///postsynaptic membrane GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005102///signaling receptor binding+++GO:0015057///thrombin-activated receptor activity+++GO:0031681///G-protein beta-subunit binding+++GO:0032795///heterotrimeric G-protein binding "GO:0000186///activation of MAPKK activity+++GO:0002248///connective tissue replacement involved in inflammatory response wound healing+++GO:0003105///negative regulation of glomerular filtration+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030168///platelet activation+++GO:0030193///regulation of blood coagulation+++GO:0030194///positive regulation of blood coagulation+++GO:0030335///positive regulation of cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045217///cell-cell junction maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051928///positive regulation of calcium ion transport+++GO:0051930///regulation of sensory perception of pain+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:1900134///negative regulation of renin secretion into blood stream" 140629 140629 'Ubox5' mRNA 380.91 434.48 431.93 5.37 6.01 6.44 3.63 2.79 3.38 5.94 3.266666667 296.6 222.87 267.79 415.7733333 262.42 1.01E-05 -0.68086935 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0016604///nuclear body GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0044528///regulation of mitochondrial mRNA stability 14063 14063 'F2rl1' mRNA 7 7 6 0.14 0.14 0.13 0.61 0.64 0.72 0.136666667 0.656666667 35 36 40 6.666666667 37 2.03E-05 2.463332667 04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels+++05143///African trypanosomiasis GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031143///pseudopodium GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0015057///thrombin-activated receptor activity+++GO:0031681///G-protein beta-subunit binding+++GO:0032795///heterotrimeric G-protein binding "GO:0002286///T cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0003104///positive regulation of glomerular filtration+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007596///blood coagulation+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030193///regulation of blood coagulation+++GO:0030335///positive regulation of cell migration+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0032682///negative regulation of chemokine production+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0034140///negative regulation of toll-like receptor 3 signaling pathway+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0042119///neutrophil activation+++GO:0042311///vasodilation+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043311///positive regulation of eosinophil degranulation+++GO:0043547///positive regulation of GTPase activity+++GO:0045087///innate immune response+++GO:0045217///cell-cell junction maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046328///regulation of JNK cascade+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0050900///leukocyte migration+++GO:0050921///positive regulation of chemotaxis+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051607///defense response to virus+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0061028///establishment of endothelial barrier+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0070661///leukocyte proliferation+++GO:0070963///positive regulation of neutrophil mediated killing of gram-negative bacterium+++GO:0097029///mature conventional dendritic cell differentiation+++GO:1900135///positive regulation of renin secretion into blood stream+++GO:2000341///regulation of chemokine (C-X-C motif) ligand 2 production" 140630 140630 'Ube4a' mRNA 937.74 884.38 767.52 10.92 9.26 9.25 9.64 8.15 9.25 9.81 9.013333333 969.97 915.64 933.27 863.2133333 939.6266667 0.299140156 0.112972911 04120///Ubiquitin mediated proteolysis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway 14064 14064 'F2rl2' mRNA 26 31 39 0.59 0.69 0.94 0.71 0.54 0.43 0.74 0.56 36 27 21 32 28 0.734401559 -0.214492108 04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032991///protein-containing complex GO:0004930///G protein-coupled receptor activity+++GO:0015057///thrombin-activated receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0070493///thrombin-activated receptor signaling pathway 14065 14065 'F2rl3' mRNA 6 4 7 0.17 0.11 0.21 0.3 0.46 0.44 0.163333333 0.4 12 18 17.01 5.666666667 15.67 0.079287967 1.452212932 04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04611///Platelet activation+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0015057///thrombin-activated receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0070493///thrombin-activated receptor signaling pathway 14066 14066 'F3' mRNA 4516 4625 4421 138.05 139.32 143.38 131.3 135.24 130.67 140.25 132.4033333 4937 4964 4755 4520.666667 4885.333333 0.119535896 0.100274437 04610///Complement and coagulation cascades+++04933///AGE-RAGE signaling pathway in diabetic complications GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:1905286///serine-type peptidase complex GO:0002020///protease binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004896///cytokine receptor activity+++GO:0005543///phospholipid binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002541///activation of plasma proteins involved in acute inflammatory response+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010628///positive regulation of gene expression+++GO:0010641///positive regulation of platelet-derived growth factor receptor signaling pathway+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016485///protein processing+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032757///positive regulation of interleukin-8 production+++GO:0045766///positive regulation of angiogenesis+++GO:0051897///positive regulation of protein kinase B signaling 14067 14067 'F5' mRNA 9 16 7 0.06 0.11 0.05 0.22 0.11 0.1 0.073333333 0.143333333 35 18 15 10.66666667 22.66666667 0.129225811 1.079304244 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0031091///platelet alpha granule GO:0005507///copper ion binding+++GO:0046872///metal ion binding GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008015///blood circulation 14068 14068 'F7' mRNA 10 3 4 0.31 0.09 0.13 9.51 9.6 9.57 0.176666667 9.56 353 348 344 5.666666667 348.3333333 3.40E-51 5.931722218 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031982///vesicle+++GO:1905286///serine-type peptidase complex GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0001666///response to hypoxia+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0007623///circadian rhythm+++GO:0009725///response to hormone+++GO:0010037///response to carbon dioxide+++GO:0010641///positive regulation of platelet-derived growth factor receptor signaling pathway+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0030194///positive regulation of blood coagulation+++GO:0031100///animal organ regeneration+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0032571///response to vitamin K+++GO:0033595///response to genistein+++GO:0043627///response to estrogen+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060416///response to growth hormone+++GO:0061476///response to anticoagulant+++GO:0070723///response to cholesterol+++GO:0097066///response to thyroid hormone+++GO:0097068///response to thyroxine+++GO:1904400///response to Thyroid stimulating hormone+++GO:1904612///response to 2,3,7,8-tetrachlorodibenzodioxine+++GO:1905217///response to astaxanthin+++GO:1905225///response to thyrotropin-releasing hormone" 14069 14069 'F8' mRNA 353 334 340 2.2 1.94 2.29 0.42 0.43 0.6 2.143333333 0.483333333 76 75 102 342.3333333 84.33333333 1.75E-27 -2.033286387 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding "GO:0006953///acute-phase response+++GO:0007596///blood coagulation+++GO:0007597///blood coagulation, intrinsic pathway+++GO:0007599///hemostasis" 14070 14070 'F8a' mRNA 663 714 609 14.84 15.73 14.46 11.21 10.8 10.77 15.01 10.92666667 576 542 536 662 551.3333333 0.01415309 -0.273960927 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016604///nuclear body GO:0005515///protein binding GO:0099518///vesicle cytoskeletal trafficking+++GO:1901799///negative regulation of proteasomal protein catabolic process 140703 140703 'Emid1' mRNA 1870 1954 1993 55.65 57.14 62.79 37.27 38.34 36.86 58.52666667 37.49 1435 1414 1380 1939 1409.666667 3.65E-09 -0.473489372 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding 140709 140709 'Col26a1' mRNA 114.28 109.9 96 2.29 2.16 2.09 6.21 5.08 5.68 2.18 5.656666667 336 267.01 302.13 106.7266667 301.7133333 1.36E-16 1.492913368 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0031012///extracellular matrix GO:0005515///protein binding GO:0010811///positive regulation of cell-substrate adhesion 14071 14071 'F9' mRNA 0 0 1 0 0 0.02 0.09 0.28 0.18 0.006666667 0.183333333 5 15 10 0.333333333 10 0.003811386 4.800063083 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0031638///zymogen activation 140721 140721 'Caskin2' mRNA 2368 2449 1904 26.94 27.41 22.93 14.74 13.27 13.03 25.76 13.68 1495 1318 1291 2240.333333 1368 2.17E-17 -0.719793914 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0003674///molecular_function 140723 140723 'Cacng5' mRNA 11 16 15 0.16 0.23 0.23 0.06 0.04 0.05 0.206666667 0.05 5 3 4 14 4 0.042151105 -1.823925659 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005245///voltage-gated calcium channel activity+++GO:0016247///channel regulator activity "GO:0006816///calcium ion transport+++GO:0019226///transmission of nerve impulse+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070588///calcium ion transmembrane transport+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099590///neurotransmitter receptor internalization+++GO:2000311///regulation of AMPA receptor activity" 14073 14073 'Faah' mRNA 884 944 909 12.5 13.13 13.64 13.02 13.79 12.32 13.09 13.04333333 1060 1096 971 912.3333333 1042.333333 0.08138672 0.180245449 04361///Axon regeneration+++04723///Retrograde endocannabinoid signaling GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031090///organelle membrane "GO:0004040///amidase activity+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017064///fatty acid amide hydrolase activity+++GO:0042802///identical protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0102077///oleamide hydrolase activity+++GO:0103073///anandamide amidohydrolase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0016042///lipid catabolic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0052651///monoacylglycerol catabolic process 140740 140740 'Sec63' mRNA 564 641 526 4.96 5.56 4.92 7.33 6.18 6.58 5.146666667 6.696666667 959 789 827 577 858.3333333 2.52E-07 0.562101065 03060///Protein export+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031207///Sec62/Sec63 complex GO:0003723///RNA binding+++GO:0008320///protein transmembrane transporter activity "GO:0001889///liver development+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0006807///nitrogen compound metabolic process+++GO:0010259///multicellular organism aging+++GO:0015031///protein transport+++GO:0031204///posttranslational protein targeting to membrane, translocation" 140741 140741 'Gpr6' mRNA 0 1 0 0 0.03 0 0 0.2 0.06 0.01 0.086666667 0 7 2 0.333333333 3 0.242440592 3.073938977 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0038036///sphingosine-1-phosphate receptor activity GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019222///regulation of metabolic process 140742 140742 'Sesn1' mRNA 2258 2517 2262 47.12 51.96 50.35 43.78 43.22 42.08 49.81 43.02666667 2402 2339 2248 2345.666667 2329.666667 0.837930448 -0.021055016 04115///p53 signaling pathway+++04211///Longevity regulating pathway GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0061700///GATOR2 complex "GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0051920///peroxiredoxin activity+++GO:0070728///leucine binding" GO:0016239///positive regulation of macroautophagy+++GO:0030308///negative regulation of cell growth+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0051896///regulation of protein kinase B signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:0072593///reactive oxygen species metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1901031///regulation of response to reactive oxygen species+++GO:1904262///negative regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 140743 140743 'Rem2' mRNA 363 337 369 11.02 10.3 11.89 1.96 1.71 1.94 11.07 1.87 74 63 71 356.3333333 69.33333333 3.10E-37 -2.376409229 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005525///GTP binding GO:0007165///signal transduction 140765 140765 'Tmprss3' mRNA 2148 2161 2091 42.7 42.34 43.9 19.4 18.04 16.79 42.98 18.07666667 1130 1028 960 2133.333333 1039.333333 1.26E-40 -1.050248912 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017080///sodium channel regulator activity GO:0006508///proteolysis+++GO:0006883///cellular sodium ion homeostasis+++GO:0006897///endocytosis+++GO:0007605///sensory perception of sound 14077 14077 'Fabp3' mRNA 858.76 883.72 847.28 91.3 93.34 95.61 77.48 95.53 82.87 93.41666667 85.29333333 832.79 998.87 859.13 863.2533333 896.93 0.754810494 0.045032864 03320///PPAR signaling pathway GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016528///sarcoplasm GO:0005324///long-chain fatty acid transporter activity+++GO:0005504///fatty acid binding+++GO:0008092///cytoskeletal protein binding+++GO:0008289///lipid binding+++GO:0036041///long-chain fatty acid binding+++GO:0050543///icosatetraenoic acid binding+++GO:0070538///oleic acid binding GO:0006631///fatty acid metabolic process+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0032365///intracellular lipid transport+++GO:0032868///response to insulin+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0046320///regulation of fatty acid oxidation+++GO:0050873///brown fat cell differentiation+++GO:0055091///phospholipid homeostasis+++GO:0070542///response to fatty acid+++GO:0071073///positive regulation of phospholipid biosynthetic process+++GO:0140214///positive regulation of long-chain fatty acid import into cell+++GO:2001245///regulation of phosphatidylcholine biosynthetic process 140780 140780 'Bmp2k' mRNA 416.11 386.61 442.46 2.39 2.21 2.73 5.85 5.28 5.71 2.443333333 5.613333333 1177.28 1033.69 1096.63 415.06 1102.533333 2.99E-38 1.394656021 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019208///phosphatase regulator activity+++GO:0035612///AP-2 adaptor complex binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030500///regulation of bone mineralization+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:2000369///regulation of clathrin-dependent endocytosis 140781 140781 'Myh7' mRNA 0 0 0.98 0 0 0.01 0 0.02 0 0.003333333 0.006666667 0 2 0 0.326666667 0.666666667 0.748435514 1.869360348 04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005859///muscle myosin complex+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0032982///myosin filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0002026///regulation of the force of heart contraction+++GO:0002027///regulation of heart rate+++GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007512///adult heart development+++GO:0014728///regulation of the force of skeletal muscle contraction+++GO:0014883///transition between fast and slow fiber+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0030049///muscle filament sliding+++GO:0031449///regulation of slow-twitch skeletal muscle fiber contraction+++GO:0046034///ATP metabolic process+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction 140792 140792 'Colec12' mRNA 1446.15 1481.52 1505.06 23.76 23.95 26.23 47.43 47.48 48.11 24.64666667 47.67333333 3322.26 3248.75 3263.69 1477.576667 3278.233333 3.53E-60 1.136612355 04145///Phagosome GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005044///scavenger receptor activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0038187///pattern recognition receptor activity+++GO:0046872///metal ion binding "GO:0006910///phagocytosis, recognition+++GO:0006955///immune response+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0071360///cellular response to exogenous dsRNA" 140795 140795 'P2ry14' mRNA 118 96 111 3.59 2.87 3.67 6.64 7.29 5.86 3.376666667 6.596666667 237 255 209 108.3333333 233.6666667 5.35E-08 1.096072282 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0061484///hematopoietic stem cell homeostasis 140806 140806 'Il25' mRNA 88 87 69 5.21 5.09 4.34 1.55 1.27 1.5 4.88 1.44 30 24 28 81.33333333 27.33333333 4.06E-06 -1.581894396 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0030380///interleukin-17E receptor binding GO:0002437///inflammatory response to antigenic stimulus+++GO:0006954///inflammatory response+++GO:0009620///response to fungus+++GO:0009624///response to nematode+++GO:0030222///eosinophil differentiation+++GO:0032616///interleukin-13 production+++GO:0032634///interleukin-5 production+++GO:0035745///T-helper 2 cell cytokine production+++GO:0045944///positive regulation of transcription by RNA polymerase II 14081 14081 'Acsl1' mRNA 3827 3896 3924 52.28 53.11 57.82 29.94 30.48 30.26 54.40333333 30.22666667 2513 2464 2462 3882.333333 2479.666667 4.20E-24 -0.65985602 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome+++04216///Ferroptosis+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0043758///acetate-CoA ligase (ADP-forming) activity+++GO:0047676///arachidonate-CoA ligase activity+++GO:0050197///phytanate-CoA ligase activity+++GO:0070251///pristanate-CoA ligase activity+++GO:0090434///oleoyl-CoA ligase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007584///response to nutrient+++GO:0008610///lipid biosynthetic process+++GO:0010033///response to organic substance+++GO:0010747///positive regulation of plasma membrane long-chain fatty acid transport+++GO:0014070///response to organic cyclic compound+++GO:0015908///fatty acid transport+++GO:0019432///triglyceride biosynthetic process+++GO:0033211///adiponectin-activated signaling pathway+++GO:0034201///response to oleic acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042178///xenobiotic catabolic process+++GO:0042493///response to drug+++GO:0044539///long-chain fatty acid import+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0120162///positive regulation of cold-induced thermogenesis 140810 140810 'Ttbk2' mRNA 498.73 466.02 405.99 2.34 2.15 2.06 1.33 1.26 1.47 2.183333333 1.353333333 324.45 296.02 345 456.9133333 321.8233333 1.70E-04 -0.513819447 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005875///microtubule associated complex+++GO:0005929///cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019894///kinesin binding+++GO:0048156///tau protein binding+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007224///smoothened signaling pathway+++GO:0007611///learning or memory+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021549///cerebellum development+++GO:0021681///cerebellar granular layer development+++GO:0021915///neural tube development+++GO:0021935///cerebellar granule cell precursor tangential migration+++GO:0030030///cell projection organization+++GO:0030334///regulation of cell migration+++GO:0030900///forebrain development+++GO:0032091///negative regulation of protein binding+++GO:0032273///positive regulation of protein polymerization+++GO:0042733///embryonic digit morphogenesis+++GO:0060271///cilium assembly+++GO:1902817///negative regulation of protein localization to microtubule+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1903828///negative regulation of cellular protein localization+++GO:1903980///positive regulation of microglial cell activation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:1904527///negative regulation of microtubule binding+++GO:1990403///embryonic brain development+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 14082 14082 'Fadd' mRNA 466.75 494.59 428.95 8.94 9.33 8.72 10.16 11.83 9.22 8.996666667 10.40333333 610 694.03 535.87 463.43 613.3 0.002773308 0.397036634 01524///Platinum drug resistance+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05142///Chagas disease+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031264///death-inducing signaling complex+++GO:0031265///CD95 death-inducing signaling complex+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0097342///ripoptosome GO:0002020///protease binding+++GO:0005123///death receptor binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0032813///tumor necrosis factor receptor superfamily binding+++GO:0033612///receptor serine/threonine kinase binding+++GO:0035877///death effector domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0089720///caspase binding "GO:0001822///kidney development+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002821///positive regulation of adaptive immune response+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0030217///T cell differentiation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033077///T cell differentiation in thymus+++GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042220///response to cocaine+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043278///response to morphine+++GO:0045087///innate immune response+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045862///positive regulation of proteolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048148///behavioral response to cocaine+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048738///cardiac muscle tissue development+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060544///regulation of necroptotic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070236///negative regulation of activation-induced cell death of T cells+++GO:0071260///cellular response to mechanical stimulus+++GO:0071550///death-inducing signaling complex assembly+++GO:0097049///motor neuron apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0097527///necroptotic signaling pathway+++GO:2000454///positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 14083 14083 'Ptk2' mRNA 1087 1095 1076 10.94 10.71 11.69 9.74 9.38 9.3 11.11333333 9.473333333 1069 1014 978 1086 1020.333333 0.313379449 -0.102567313 "01522///Endocrine resistance+++04012///ErbB signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04935///Growth hormone synthesis, secretion and action+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05222///Small cell lung cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016604///nuclear body+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0036064///ciliary basal body+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008432///JUN kinase binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding GO:0000165///MAPK cascade+++GO:0000226///microtubule cytoskeleton organization+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001764///neuron migration+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006928///movement of cell or subcellular component+++GO:0007097///nuclear migration+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007172///signal complex assembly+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007254///JNK cascade+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010507///negative regulation of autophagy+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010632///regulation of epithelial cell migration+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010763///positive regulation of fibroblast migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021955///central nervous system neuron axonogenesis+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0030644///cellular chloride ion homeostasis+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0042311///vasodilation+++GO:0043066///negative regulation of apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045087///innate immune response+++GO:0045667///regulation of osteoblast differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045860///positive regulation of protein kinase activity+++GO:0046621///negative regulation of organ growth+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050766///positive regulation of phagocytosis+++GO:0050771///negative regulation of axonogenesis+++GO:0050806///positive regulation of synaptic transmission+++GO:0051893///regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051964///negative regulation of synapse assembly+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060396///growth hormone receptor signaling pathway+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090303///positive regulation of wound healing+++GO:0120041///positive regulation of macrophage proliferation+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000811///negative regulation of anoikis 14084 14084 'Faf1' mRNA 765 822 293 9.28 9.8 3.77 3.2 4.3 5.85 7.616666667 4.45 304 399 538 626.6666667 413.6666667 0.307508378 -0.586369892 04217///Necroptosis+++04624///Toll and Imd signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0051059///NF-kappaB binding GO:0006915///apoptotic process+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0008219///cell death+++GO:0010942///positive regulation of cell death+++GO:0030155///regulation of cell adhesion+++GO:0031334///positive regulation of protein complex assembly+++GO:0042176///regulation of protein catabolic process+++GO:0045740///positive regulation of DNA replication+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903364///positive regulation of cellular protein catabolic process 14085 14085 'Fah' mRNA 669 627 600 24.74 22.86 23.54 23.59 24.08 24.98 23.71333333 24.21666667 733 730 751 632 738 0.051369031 0.212884853 00350///Tyrosine metabolism GO:0003824///catalytic activity+++GO:0004334///fumarylacetoacetase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006527///arginine catabolic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0009072///aromatic amino acid family metabolic process+++GO:1902000///homogentisate catabolic process 140858 140858 'Wdr5' mRNA 785 811 773 14.87 15.09 15.57 16.59 16.58 16.38 15.17666667 16.51666667 1005 981 963 789.6666667 983 0.001141968 0.304201641 04934///Cushing syndrome GO:0000123///histone acetyltransferase complex+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex+++GO:0071339///MLL1 complex GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific) GO:0001501///skeletal system development+++GO:0006325///chromatin organization+++GO:0031175///neuron projection development+++GO:0043966///histone H3 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0051568///histone H3-K4 methylation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051572///negative regulation of histone H3-K4 methylation 140859 140859 'Nek8' mRNA 407 453 463 8.06 8.94 9.79 8.83 8.14 7.92 8.93 8.296666667 507 459 440 441 468.6666667 0.670385276 0.073135302 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097543///ciliary inversin compartment+++GO:0097546///ciliary base GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007059///chromosome segregation+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0009887///animal organ morphogenesis+++GO:0016310///phosphorylation+++GO:0035330///regulation of hippo signaling 14086 14086 'Fscn1' mRNA 2321 2272 1575 48.23 46.47 34.72 27.6 29.65 28.13 43.14 28.46 1528 1603 1508 2056 1546.333333 1.19E-04 -0.414300744 05206///MicroRNAs in cancer GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031253///cell projection membrane+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0044393///microspike+++GO:0045171///intercellular bridge "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0005515///protein binding+++GO:0008144///drug binding+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017108///5'-flap endonuclease activity+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0070336///flap-structured DNA binding+++GO:0140036///ubiquitin-dependent protein binding" "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007015///actin filament organization+++GO:0007043///cell-cell junction assembly+++GO:0007163///establishment or maintenance of cell polarity+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016477///cell migration+++GO:0030035///microspike assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030046///parallel actin filament bundle assembly+++GO:0032534///regulation of microvillus assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0035089///establishment of apical/basal cell polarity+++GO:0036297///interstrand cross-link repair+++GO:0048870///cell motility+++GO:0051017///actin filament bundle assembly+++GO:0051491///positive regulation of filopodium assembly+++GO:0071803///positive regulation of podosome assembly+++GO:0090091///positive regulation of extracellular matrix disassembly" 14087 14087 'Fanca' mRNA 956.75 952.15 1066.92 9.29 9.14 11.02 2.25 2.26 2.01 9.816666667 2.173333333 274.99 266.25 247.94 991.94 263.06 4.71E-58 -1.933637075 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043240///Fanconi anaemia nuclear complex GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007140///male meiotic nuclear division+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0036297///interstrand cross-link repair+++GO:0042127///regulation of cell proliferation+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0050727///regulation of inflammatory response+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:2000348///regulation of CD40 signaling pathway 14088 14088 'Fancc' mRNA 446 459 448 8.64 8.86 9.31 4.2 4.93 4.37 8.936666667 4.5 251 289 245 451 261.6666667 1.56E-08 -0.796574183 03460///Fanconi anemia pathway GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043240///Fanconi anaemia nuclear complex GO:0002262///myeloid cell homeostasis+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007276///gamete generation+++GO:0007281///germ cell development+++GO:0019430///removal of superoxide radicals+++GO:0034599///cellular response to oxidative stress+++GO:0036297///interstrand cross-link repair+++GO:0048854///brain morphogenesis+++GO:0097150///neuronal stem cell population maintenance 140887 140887 'Lnx2' mRNA 853 907 746 10.08 10.52 9.34 5.55 5.48 6.22 9.98 5.75 540 521 587 835.3333333 549.3333333 6.25E-09 -0.613305786 GO:0005575///cellular_component GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination 14089 14089 'Fap' mRNA 108 109 99 2.21 2.2 2.15 2.35 1.99 1.91 2.186666667 2.083333333 132 109 104 105.3333333 115 0.720293678 0.114506639 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031258///lamellipodium membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0045178///basal part of cell+++GO:1905368///peptidase complex GO:0002020///protease binding+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005178///integrin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0010710///regulation of collagen catabolic process+++GO:0010716///negative regulation of extracellular matrix disassembly+++GO:0043542///endothelial cell migration+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0051726///regulation of cell cycle+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071850///mitotic cell cycle arrest+++GO:0097325///melanocyte proliferation+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1902362///melanocyte apoptotic process+++GO:1903054///negative regulation of extracellular matrix organization 140904 140904 'Caln1' mRNA 225.35 213.08 198.37 4.43 3.99 4.25 2.41 2.58 2.26 4.223333333 2.416666667 140.68 144.07 122.92 212.2666667 135.89 6.78E-04 -0.657956898 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032588///trans-Golgi network membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 140917 140917 'Dclre1b' mRNA 297.68 351.56 275 3.75 4.34 3.68 4.7 5.38 4.69 3.923333333 4.923333333 430.22 482 415.27 308.08 442.4966667 3.61E-04 0.516147631 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body" GO:0003684///damaged DNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007093///mitotic cell cycle checkpoint+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0016233///telomere capping+++GO:0031627///telomeric loop formation+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0031860///telomeric 3' overhang formation+++GO:0036297///interstrand cross-link repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 140919 140919 'Slc17a6' mRNA 20 36 28 0.29 0.52 0.43 0.08 0.01 0.01 0.413333333 0.033333333 7 1 1 28 3 7.13E-05 -3.242964128 04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++05033///Nicotine addiction GO:0005769///early endosome+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0098793///presynapse+++GO:1990030///pericellular basket GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity "GO:0001504///neurotransmitter uptake+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0006836///neurotransmitter transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050803///regulation of synapse structure or activity+++GO:0055085///transmembrane transport+++GO:0098700///neurotransmitter loading into synaptic vesicle+++GO:1990384///hyaloid vascular plexus regression" 14102 14102 'Fas' mRNA 94 71 77 3.75 2.97 3.31 9.22 10.28 7.99 3.343333333 9.163333333 265 282 228 80.66666667 258.3333333 6.24E-16 1.668006851 01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04115///p53 signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04650///Natural killer cell mediated cytotoxicity+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05142///Chagas disease+++05143///African trypanosomiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016604///nuclear body+++GO:0030141///secretory granule+++GO:0031264///death-inducing signaling complex+++GO:0031265///CD95 death-inducing signaling complex+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite GO:0002020///protease binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002377///immunoglobulin production+++GO:0006915///apoptotic process+++GO:0006924///activation-induced cell death of T cells+++GO:0006925///inflammatory cell apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007623///circadian rhythm+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0009636///response to toxic substance+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0019724///B cell mediated immunity+++GO:0031104///dendrite regeneration+++GO:0031334///positive regulation of protein complex assembly+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034198///cellular response to amino acid starvation+++GO:0036337///Fas signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045060///negative thymic T cell selection+++GO:0045619///regulation of lymphocyte differentiation+++GO:0045637///regulation of myeloid cell differentiation+++GO:0048536///spleen development+++GO:0050869///negative regulation of B cell activation+++GO:0051384///response to glucocorticoid+++GO:0051402///neuron apoptotic process+++GO:0070227///lymphocyte apoptotic process+++GO:0071285///cellular response to lithium ion+++GO:0071455///cellular response to hyperoxia+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097049///motor neuron apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097284///hepatocyte apoptotic process+++GO:0097527///necroptotic signaling pathway+++GO:1900148///negative regulation of Schwann cell migration+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 14103 14103 'Fasl' mRNA 4 2 0 0.12 0.06 0 0.16 0.11 0.19 0.06 0.153333333 6 4 7 2 5.666666667 0.329589892 1.511332752 01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04650///Natural killer cell mediated cytotoxicity+++04722///Neurotrophin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05142///Chagas disease+++05143///African trypanosomiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043202///lysosomal lumen+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0060205///cytoplasmic vesicle lumen+++GO:0070062///extracellular exosome GO:0005123///death receptor binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006925///inflammatory cell apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0016525///negative regulation of angiogenesis+++GO:0030644///cellular chloride ion homeostasis+++GO:0032496///response to lipopolysaccharide+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0046666///retinal cell programmed cell death+++GO:0048388///endosomal lumen acidification+++GO:0070231///T cell apoptotic process+++GO:0070266///necroptotic process+++GO:0070848///response to growth factor+++GO:0071346///cellular response to interferon-gamma+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097527///necroptotic signaling pathway+++GO:1903514///release of sequestered calcium ion into cytosol by endoplasmic reticulum+++GO:1905782///positive regulation of phosphatidylserine exposure on apoptotic cell surface+++GO:2000353///positive regulation of endothelial cell apoptotic process 14104 14104 'Fasn' mRNA 7035 6936 6509 39.06 37.86 38.44 24.56 20.96 22.79 38.45333333 22.77 5087 4227 4570 6826.666667 4628 6.62E-20 -0.573429286 00061///Fatty acid biosynthesis+++01212///Fatty acid metabolism+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04936///Alcoholic liver disease GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0042470///melanosome+++GO:0042587///glycogen granule "GO:0003824///catalytic activity+++GO:0004312///fatty acid synthase activity+++GO:0004313///[acyl-carrier-protein] S-acetyltransferase activity+++GO:0004314///[acyl-carrier-protein] S-malonyltransferase activity+++GO:0004315///3-oxoacyl-[acyl-carrier-protein] synthase activity+++GO:0004316///3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity+++GO:0004317///3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity+++GO:0004320///oleoyl-[acyl-carrier-protein] hydrolase activity+++GO:0008659///(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity+++GO:0008693///3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity+++GO:0016295///myristoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016296///palmitoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016297///acyl-[acyl-carrier-protein] hydrolase activity+++GO:0016418///S-acetyltransferase activity+++GO:0016419///S-malonyltransferase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0019171///3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity+++GO:0031177///phosphopantetheine binding+++GO:0042802///identical protein binding+++GO:0047117///enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity+++GO:0047451///3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity+++GO:0102131///3-oxo-glutaryl-[acp] methyl ester reductase activity+++GO:0102132///3-oxo-pimeloyl-[acp] methyl ester reductase activity" GO:0002068///glandular epithelial cell development+++GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0008611///ether lipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0009888///tissue development+++GO:0030223///neutrophil differentiation+++GO:0030224///monocyte differentiation+++GO:0030879///mammary gland development+++GO:0071353///cellular response to interleukin-4+++GO:0090557///establishment of endothelial intestinal barrier 14105 14105 'Srsf10' mRNA 1945 2006 2050 36.27 36.63 40.57 35.96 35.07 35.44 37.82333333 35.49 2227 2123 2131 2000.333333 2160.333333 0.258893079 0.097323655 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0051082///unfolded protein binding "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0016482///cytosolic transport+++GO:0043484///regulation of RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 14106 14106 'Foxh1' mRNA 0 1.13 1 0 0.03 0.05 0.14 0.12 0.12 0.026666667 0.126666667 4.31 3 3 0.71 3.436666667 0.279317611 2.300626996 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0032444///activin responsive factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0050681///androgen receptor binding+++GO:0070410///co-SMAD binding+++GO:0070412///R-SMAD binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001947///heart looping+++GO:0003139///secondary heart field specification+++GO:0003151///outflow tract morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0009952///anterior/posterior pattern specification+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035054///embryonic heart tube anterior/posterior pattern specification+++GO:0035909///aorta morphogenesis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048318///axial mesoderm development+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0071345///cellular response to cytokine stimulus" 14107 14107 'Fat1' mRNA 1452 1461 1241 5.07 5.06 4.61 3.72 3.65 4.21 4.913333333 3.86 1227 1187 1342 1384.666667 1252 0.102180951 -0.154126432 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0002088///lens development in camera-type eye+++GO:0003382///epithelial cell morphogenesis+++GO:0003412///establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007163///establishment or maintenance of cell polarity+++GO:0016477///cell migration+++GO:0043010///camera-type eye development+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0048593///camera-type eye morphogenesis+++GO:0098609///cell-cell adhesion 14109 14109 'Fau' mRNA 5034 4776 4941 799.23 758.77 833.79 949.22 1060.16 1049.29 797.2633333 1019.556667 6844 7411 7245 4917 7166.666667 2.58E-15 0.531415913 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005615///extracellular space+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0002227///innate immune response in mucosa+++GO:0006412///translation+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 14113 14113 'Fbl' mRNA 853 825 595 44.46 42.65 33.29 38.7 53.9 51.43 40.13333333 48.01 845 1155 1096 757.6666667 1032 0.001800904 0.444148376 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0001651///dense fibrillar component+++GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0015030///Cajal body+++GO:0031428///box C/D snoRNP complex+++GO:0032040///small-subunit processome GO:0001094///TFIID-class transcription factor complex binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0051117///ATPase binding+++GO:1990259///histone-glutamine methyltransferase activity GO:0000494///box C/D snoRNA 3'-end processing+++GO:0006364///rRNA processing+++GO:0016074///snoRNA metabolic process+++GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0048254///snoRNA localization+++GO:1990258///histone glutamine methylation 14114 14114 'Fbln1' mRNA 1693 1649 1526 38.51 36.69 36.42 114.57 117.78 119.22 37.20666667 117.19 5975 5931 5993 1622.666667 5966.333333 1.05E-226 1.868040734 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0001968///fibronectin binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016504///peptidase activator activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0070051///fibrinogen binding "GO:0001933///negative regulation of protein phosphorylation+++GO:0007162///negative regulation of cell adhesion+++GO:0007566///embryo implantation+++GO:0010628///positive regulation of gene expression+++GO:0010952///positive regulation of peptidase activity+++GO:0030198///extracellular matrix organization+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071635///negative regulation of transforming growth factor beta production+++GO:0072378///blood coagulation, fibrin clot formation+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1904188///negative regulation of transformation of host cell by virus+++GO:1904237///positive regulation of substrate-dependent cell migration, cell attachment to substrate+++GO:2000146///negative regulation of cell motility+++GO:2000647///negative regulation of stem cell proliferation" 14115 14115 'Fbln2' mRNA 2595 2621 2775 32.1 31.88 36.41 13.99 13.84 14.02 33.46333333 13.95 1309 1267 1268 2663.666667 1281.333333 1.98E-42 -1.070152061 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0050840///extracellular matrix binding GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization 14118 14118 'Fbn1' mRNA 238 265 227 1.26 1.38 1.27 2.81 2.56 2.4 1.303333333 2.59 611 545 505 243.3333333 553.6666667 8.31E-19 1.174920509 04350///TGF-beta signaling pathway GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005179///hormone activity+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008061///chitin binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001501///skeletal system development+++GO:0001656///metanephros development+++GO:0001822///kidney development+++GO:0006006///glucose metabolic process+++GO:0007507///heart development+++GO:0009653///anatomical structure morphogenesis+++GO:0010737///protein kinase A signaling+++GO:0033627///cell adhesion mediated by integrin+++GO:0034199///activation of protein kinase A activity+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0035583///sequestering of TGFbeta in extracellular matrix+++GO:0042593///glucose homeostasis+++GO:0043010///camera-type eye development+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048048///embryonic eye morphogenesis+++GO:0048050///post-embryonic eye morphogenesis+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2001205///negative regulation of osteoclast development 14119 14119 'Fbn2' mRNA 232 249 172 1.15 1.22 0.9 0.75 0.82 0.71 1.09 0.76 174 185 158 217.6666667 172.3333333 0.099665307 -0.341886645 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0009653///anatomical structure morphogenesis+++GO:0030326///embryonic limb morphogenesis+++GO:0030501///positive regulation of bone mineralization+++GO:0035108///limb morphogenesis+++GO:0035583///sequestering of TGFbeta in extracellular matrix+++GO:0043010///camera-type eye development+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048048///embryonic eye morphogenesis+++GO:0060346///bone trabecula formation 14120 14120 'Fbp2' mRNA 358 411 416 16.29 18.46 20.09 19.74 19.26 18.61 18.28 19.20333333 498 474 454 395 475.3333333 0.07628764 0.252952039 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++01200///Carbon metabolism+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0030054///cell junction "GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" "GO:0005975///carbohydrate metabolic process+++GO:0005986///sucrose biosynthetic process+++GO:0006000///fructose metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0008152///metabolic process+++GO:0030388///fructose 1,6-bisphosphate metabolic process" 14121 14121 'Fbp1' mRNA 116 111 91 4.61 4.35 3.87 8.24 9.04 7.03 4.276666667 8.103333333 238 253 195 106 228.6666667 6.54E-08 1.101087355 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++01200///Carbon metabolism+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane "GO:0001085///RNA polymerase II transcription factor binding+++GO:0003824///catalytic activity+++GO:0016208///AMP binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0005975///carbohydrate metabolic process+++GO:0005986///sucrose biosynthetic process+++GO:0006000///fructose metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006111///regulation of gluconeogenesis+++GO:0008152///metabolic process+++GO:0016311///dephosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0035690///cellular response to drug+++GO:0045820///negative regulation of glycolytic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0071286///cellular response to magnesium ion+++GO:0071466///cellular response to xenobiotic stimulus" 14123 14123 'Fbrs' mRNA 857 775 672 9.28 8.21 7.6 7.58 7.29 7.79 8.363333333 7.553333333 754 711 758 768 741 0.659984076 -0.060523506 GO:0005615///extracellular space GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0048146///positive regulation of fibroblast proliferation 14125 14125 'Fcer1a' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04664///Fc epsilon RI signaling pathway+++05310///Asthma GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019767///IgE receptor activity+++GO:0019863///IgE binding GO:0000187///activation of MAPK activity+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0001820///serotonin secretion+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0019370///leukotriene biosynthetic process+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032752///positive regulation of interleukin-3 production+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050776///regulation of immune response+++GO:0050850///positive regulation of calcium-mediated signaling 14126 14126 'Ms4a2' mRNA 16 14 17 0.33 0.32 0.37 0.05 0.02 0 0.34 0.023333333 3 1 0 15.66666667 1.333333333 0.001352995 -3.576939582 04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04664///Fc epsilon RI signaling pathway+++05310///Asthma GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032998///Fc-epsilon receptor I complex+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0005154///epidermal growth factor receptor binding+++GO:0019767///IgE receptor activity+++GO:0019863///IgE binding+++GO:0019865///immunoglobulin binding+++GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding GO:0002115///store-operated calcium entry+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0030183///B cell differentiation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0042113///B cell activation+++GO:0043306///positive regulation of mast cell degranulation+++GO:0050853///B cell receptor signaling pathway+++GO:0051262///protein tetramerization+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:1902656///calcium ion import into cytosol 14127 14127 'Fcer1g' mRNA 551 519 513 61.38 57.47 60.65 904.54 999.4 872.94 59.83333333 925.6266667 9275 9967 8632 527.6666667 9291.333333 0 4.127412648 04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04611///Platelet activation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04664///Fc epsilon RI signaling pathway+++05152///Tuberculosis+++05310///Asthma GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032998///Fc-epsilon receptor I complex+++GO:0045121///membrane raft GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019767///IgE receptor activity+++GO:0019863///IgE binding+++GO:0019864///IgG binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0001798///positive regulation of type IIa hypersensitivity+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0002283///neutrophil activation involved in immune response+++GO:0002292///T cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0002431///Fc receptor mediated stimulatory signaling pathway+++GO:0002554///serotonin secretion by platelet+++GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0010543///regulation of platelet activation+++GO:0016064///immunoglobulin mediated immune response+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030316///osteoclast differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0031623///receptor internalization+++GO:0032623///interleukin-2 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032765///positive regulation of mast cell cytokine production+++GO:0033026///negative regulation of mast cell apoptotic process+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0038156///interleukin-3-mediated signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0042742///defense response to bacterium+++GO:0043306///positive regulation of mast cell degranulation+++GO:0045087///innate immune response+++GO:0045576///mast cell activation+++GO:0050766///positive regulation of phagocytosis+++GO:0050776///regulation of immune response+++GO:0050778///positive regulation of immune response+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0072659///protein localization to plasma membrane+++GO:2000010///positive regulation of protein localization to cell surface" 14128 14128 'Fcer2a' mRNA 32.72 45.47 37.2 0.45 0.61 0.54 0.3 0.43 0.28 0.533333333 0.336666667 25 33.48 20.59 38.46333333 26.35666667 0.271377087 -0.55636965 04640///Hematopoietic cell lineage+++05169///Epstein-Barr virus infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019863///IgE binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0044419///interspecies interaction between organisms+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process 14129 14129 'Fcgr1' mRNA 224 197 174 4.81 4.16 3.96 44.13 42.06 43.52 4.31 43.23666667 2366 2202 2259 198.3333333 2275.666667 3.98E-285 3.510154887 04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage+++04666///Fc gamma R-mediated phagocytosis+++05140///Leishmaniasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia+++05322///Systemic lupus erythematosus GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0004888///transmembrane signaling receptor activity+++GO:0019770///IgG receptor activity+++GO:0019864///IgG binding+++GO:0031774///leukotriene receptor binding "GO:0001788///antibody-dependent cellular cytotoxicity+++GO:0001798///positive regulation of type IIa hypersensitivity+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0002376///immune system process+++GO:0006898///receptor-mediated endocytosis+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0007166///cell surface receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050766///positive regulation of phagocytosis+++GO:0050776///regulation of immune response+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:1904058///positive regulation of sensory perception of pain" 14130 14130 'Fcgr2b' mRNA 254.87 296.36 258.88 10.8 12.33 11.66 186.82 201.08 193.9 11.59666667 193.9333333 5068.94 5325.89 5089.1 270.0366667 5161.31 0 4.250123501 04145///Phagosome+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05162///Measles GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043197///dendritic spine+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0055037///recycling endosome GO:0001540///amyloid-beta binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019772///low-affinity IgG receptor activity+++GO:0019864///IgG binding+++GO:0019865///immunoglobulin binding+++GO:0044877///protein-containing complex binding "GO:0001811///negative regulation of type I hypersensitivity+++GO:0002434///immune complex clearance+++GO:0002638///negative regulation of immunoglobulin production+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0002865///negative regulation of acute inflammatory response to antigenic stimulus+++GO:0002924///negative regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006898///receptor-mediated endocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0006952///defense response+++GO:0007166///cell surface receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0016064///immunoglobulin mediated immune response+++GO:0016358///dendrite development+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0021549///cerebellum development+++GO:0030889///negative regulation of B cell proliferation+++GO:0032456///endocytic recycling+++GO:0032693///negative regulation of interleukin-10 production+++GO:0033030///negative regulation of neutrophil apoptotic process+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0045576///mast cell activation+++GO:0046330///positive regulation of JNK cascade+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0050765///negative regulation of phagocytosis+++GO:0050766///positive regulation of phagocytosis+++GO:0050776///regulation of immune response+++GO:0050777///negative regulation of immune response+++GO:0050859///negative regulation of B cell receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0071219///cellular response to molecule of bacterial origin+++GO:1901216///positive regulation of neuron death+++GO:1902950///regulation of dendritic spine maintenance+++GO:1904646///cellular response to amyloid-beta+++GO:1905898///positive regulation of response to endoplasmic reticulum stress" 14131 14131 'Fcgr3' mRNA 497.13 486.64 515.12 22.06 21.37 24.27 269.4 289.79 269.67 22.56666667 276.2866667 6957.06 7301.11 6741.9 499.63 7000.023333 0 3.796986479 04145///Phagosome+++04380///Osteoclast differentiation+++05140///Leishmaniasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0019770///IgG receptor activity+++GO:0019864///IgG binding+++GO:0034987///immunoglobulin receptor binding "GO:0001788///antibody-dependent cellular cytotoxicity+++GO:0001798///positive regulation of type IIa hypersensitivity+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0001820///serotonin secretion+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0007166///cell surface receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0045576///mast cell activation+++GO:0050766///positive regulation of phagocytosis+++GO:0050776///regulation of immune response" 14132 14132 'Fcgrt' mRNA 3645 3847 4021 121.24 126.14 141.93 188.31 197.75 186.09 129.77 190.7166667 6504 6667 6219 3837.666667 6463.333333 4.77E-25 0.737982323 GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019864///IgG binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042605///peptide antigen binding GO:0006955///immune response 14133 14133 'Fcna' mRNA 27 32 40 1.24 1.46 1.96 59.87 64.06 54.68 1.553333333 59.53666667 1494 1560 1322 33 1458.666667 1.49E-204 5.453746525 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0001664///G protein-coupled receptor binding+++GO:0003823///antigen binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0038187///pattern recognition receptor activity+++GO:0043394///proteoglycan binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0097367///carbohydrate derivative binding+++GO:2001065///mannan binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0002752///cell surface pattern recognition receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032757///positive regulation of interleukin-8 production+++GO:0045087///innate immune response" 14134 14134 'Fcnb' mRNA 7 2 4 0.42 0.12 0.21 0.1 0.11 0.05 0.25 0.086666667 2 2 1 4.333333333 1.666666667 0.410100448 -1.392629579 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0001664///G protein-coupled receptor binding+++GO:0003823///antigen binding+++GO:0005102///signaling receptor binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0038187///pattern recognition receptor activity+++GO:0043394///proteoglycan binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0097367///carbohydrate derivative binding+++GO:2001065///mannan binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0002752///cell surface pattern recognition receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034394///protein localization to cell surface+++GO:0043654///recognition of apoptotic cell+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell" 14137 14137 'Fdft1' mRNA 3854.23 3994.7 3708.9 68.25 70.23 69.41 22.38 23.19 22.31 69.29666667 22.62666667 1433.23 1442.1 1391.63 3852.61 1422.32 2.71E-116 -1.448762587 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004310///farnesyl-diphosphate farnesyltransferase activity+++GO:0004311///farnesyltranstransferase activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0046872///metal ion binding+++GO:0051996///squalene synthase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008152///metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0008610///lipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0045338///farnesyl diphosphate metabolic process 14148 14148 'Fdx1' mRNA 556 642 608 27.57 31.13 31.85 31.58 34.5 36.76 30.18333333 34.28 736 775 824 602 778.3333333 0.001829862 0.359033866 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0030061///mitochondrial crista "GO:0005506///iron ion binding+++GO:0008386///cholesterol monooxygenase (side-chain-cleaving) activity+++GO:0009055///electron transfer activity+++GO:0015039///NADPH-adrenodoxin reductase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0022900///electron transport chain+++GO:0042446///hormone biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0070995///NADPH oxidation+++GO:0071320///cellular response to cAMP+++GO:1904322///cellular response to forskolin 14149 14149 'Fdxr' mRNA 453 419 366 13.88 12.66 11.91 8.39 9.15 9.42 12.81666667 8.986666667 315 334 341 412.6666667 330 0.021337797 -0.330843822 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0015039///NADPH-adrenodoxin reductase activity+++GO:0016491///oxidoreductase activity+++GO:0070402///NADPH binding GO:0006629///lipid metabolic process+++GO:0006744///ubiquinone biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0070995///NADPH oxidation 14151 14151 'Fech' mRNA 2316 2378 2372 43.36 43.79 47.19 34.82 36.56 36.31 44.78 35.89666667 2133 2197 2163 2355.333333 2164.333333 0.090201437 -0.134378476 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane "GO:0004325///ferrochelatase activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0020037///heme binding+++GO:0030350///iron-responsive element binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046906///tetrapyrrole binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0009416///response to light stimulus+++GO:0009589///detection of UV+++GO:0010038///response to metal ion+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0010999///regulation of eIF2 alpha phosphorylation by heme+++GO:0017085///response to insecticide+++GO:0030218///erythrocyte differentiation+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0046501///protoporphyrinogen IX metabolic process+++GO:0046685///response to arsenic-containing substance+++GO:0046984///regulation of hemoglobin biosynthetic process+++GO:0051597///response to methylmercury+++GO:0055072///iron ion homeostasis+++GO:0070541///response to platinum ion+++GO:0071549///cellular response to dexamethasone stimulus 14154 14154 'Fem1a' mRNA 946.02 929 931.96 7.33 7.08 7.66 5.43 5.46 5.6 7.356666667 5.496666667 806.97 792.97 806 935.66 801.98 0.016554207 -0.235439658 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0008134///transcription factor binding+++GO:0031867///EP4 subtype prostaglandin E2 receptor binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043407///negative regulation of MAP kinase activity+++GO:0050728///negative regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051438///regulation of ubiquitin-protein transferase activity 14155 14155 'Fem1b' mRNA 650 712 643 5.3 5.7 5.56 5.26 5.04 5.27 5.52 5.19 744 696 721 668.3333333 720.3333333 0.425076744 0.096766626 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0002070///epithelial cell maturation+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000001///regulation of DNA damage checkpoint 14156 14156 'Fen1' mRNA 226 230 239 5.64 5.71 6.32 16.46 17.6 15.9 5.89 16.65333333 752 784 699 231.6666667 745 1.85E-41 1.672647888 03030///DNA replication+++03410///Base excision repair+++03450///Non-homologous end-joining "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex" "GO:0000287///magnesium ion binding+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004527///exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017108///5'-flap endonuclease activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0048256///flap endonuclease activity" "GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007613///memory+++GO:0043137///DNA replication, removal of RNA primer+++GO:0045876///positive regulation of sister chromatid cohesion+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 14158 14158 'Fer' mRNA 841 908 827 15.07 15.19 15.58 14.32 14.58 14.26 15.28 14.38666667 863 829 818 858.6666667 836.6666667 0.696837118 -0.048718034 04520///Adherens junction GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0050839///cell adhesion molecule binding GO:0000226///microtubule cytoskeleton organization+++GO:0001932///regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006935///chemotaxis+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0010591///regulation of lamellipodium assembly+++GO:0010762///regulation of fibroblast migration+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032496///response to lipopolysaccharide+++GO:0032869///cellular response to insulin stimulus+++GO:0033007///negative regulation of mast cell activation involved in immune response+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0034614///cellular response to reactive oxygen species+++GO:0035426///extracellular matrix-cell signaling+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0036119///response to platelet-derived growth factor+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0038109///Kit signaling pathway+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0043304///regulation of mast cell degranulation+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0045087///innate immune response+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050904///diapedesis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070102///interleukin-6-mediated signaling pathway 14159 14159 'Fes' mRNA 146 173 159 2.9 3.41 3.36 23.82 21.38 22.53 3.223333333 22.57666667 1369 1202 1257 159.3333333 1276 4.71E-148 2.989086755 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0034987///immunoglobulin receptor binding+++GO:0035091///phosphatidylinositol binding GO:0001578///microtubule bundle formation+++GO:0006468///protein phosphorylation+++GO:0006935///chemotaxis+++GO:0007098///centrosome cycle+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008360///regulation of cell shape+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0031116///positive regulation of microtubule polymerization+++GO:0042127///regulation of cell proliferation+++GO:0043304///regulation of mast cell degranulation+++GO:0045087///innate immune response+++GO:0045595///regulation of cell differentiation+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0046777///protein autophosphorylation+++GO:0071305///cellular response to vitamin D+++GO:2000145///regulation of cell motility+++GO:2000251///positive regulation of actin cytoskeleton reorganization 14160 14160 'Lgr5' mRNA 56.35 107.68 94.03 0.64 1.2 1.13 0.53 0.32 0.47 0.99 0.44 54.16 32.01 46.48 86.02 44.21666667 0.007611696 -0.978881095 04310///Wnt signaling pathway GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032588///trans-Golgi network membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016500///protein-hormone receptor activity GO:0001942///hair follicle development+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0009755///hormone-mediated signaling pathway+++GO:0009994///oocyte differentiation+++GO:0042127///regulation of cell proliferation+++GO:0048839///inner ear development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis 14163 14163 'Fgd1' mRNA 96.27 72.52 64.77 1.47 1.16 1.07 1.54 1.17 2.04 1.233333333 1.583333333 116.7 87.39 144.34 77.85333333 116.1433333 0.058264426 0.571754378 04810///Regulation of actin cytoskeleton GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0043087///regulation of GTPase activity+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 14164 14164 'Fgf1' mRNA 1193 1144 1115 14.06 13.33 14.18 11.37 9.33 9.97 13.85666667 10.22333333 1044 830 883 1150.666667 919 7.04E-04 -0.337907024 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04390///Hippo signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0031012///extracellular matrix GO:0005104///fibroblast growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0030544///Hsp70 protein binding+++GO:0044548///S100 protein binding "GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001759///organ induction+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0032148///activation of protein kinase B activity+++GO:0034605///cellular response to heat+++GO:0042060///wound healing+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051781///positive regulation of cell division+++GO:0060038///cardiac muscle cell proliferation+++GO:0060681///branch elongation involved in ureteric bud branching+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072163///mesonephric epithelium development+++GO:1901509///regulation of endothelial tube morphogenesis+++GO:1902533///positive regulation of intracellular signal transduction+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000544///regulation of endothelial cell chemotaxis to fibroblast growth factor" 14165 14165 'Fgf10' mRNA 1337 1323 1249 15.68 15.26 15.54 3.48 3.37 3.48 15.49333333 3.443333333 342 323 331 1303 332 5.91E-96 -1.98405364 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0062023///collagen-containing extracellular matrix GO:0005104///fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0042056///chemoattractant activity "GO:0000132///establishment of mitotic spindle orientation+++GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001656///metanephros development+++GO:0001759///organ induction+++GO:0001823///mesonephros development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001974///blood vessel remodeling+++GO:0003338///metanephros morphogenesis+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007368///determination of left/right symmetry+++GO:0007431///salivary gland development+++GO:0007435///salivary gland morphogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008544///epidermis development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0014070///response to organic cyclic compound+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0030538///embryonic genitalia morphogenesis+++GO:0030855///epithelial cell differentiation+++GO:0030878///thyroid gland development+++GO:0030916///otic vesicle formation+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031016///pancreas development+++GO:0031069///hair follicle morphogenesis+++GO:0031076///embryonic camera-type eye development+++GO:0031532///actin cytoskeleton reorganization+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032781///positive regulation of ATPase activity+++GO:0032808///lacrimal gland development+++GO:0032925///regulation of activin receptor signaling pathway+++GO:0034394///protein localization to cell surface+++GO:0035019///somatic stem cell population maintenance+++GO:0035108///limb morphogenesis+++GO:0035265///organ growth+++GO:0042060///wound healing+++GO:0042246///tissue regeneration+++GO:0042472///inner ear morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042693///muscle cell fate commitment+++GO:0043410///positive regulation of MAPK cascade+++GO:0045596///negative regulation of cell differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046877///regulation of saliva secretion+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048286///lung alveolus development+++GO:0048514///blood vessel morphogenesis+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048565///digestive tract development+++GO:0048566///embryonic digestive tract development+++GO:0048645///animal organ formation+++GO:0048730///epidermis morphogenesis+++GO:0048752///semicircular canal morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048807///female genitalia morphogenesis+++GO:0048808///male genitalia morphogenesis+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050673///epithelial cell proliferation+++GO:0050674///urothelial cell proliferation+++GO:0050677///positive regulation of urothelial cell proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050872///white fat cell differentiation+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051145///smooth muscle cell differentiation+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051726///regulation of cell cycle+++GO:0060019///radial glial cell differentiation+++GO:0060173///limb development+++GO:0060174///limb bud formation+++GO:0060425///lung morphogenesis+++GO:0060428///lung epithelium development+++GO:0060430///lung saccule development+++GO:0060436///bronchiole morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060447///bud outgrowth involved in lung branching+++GO:0060449///bud elongation involved in lung branching+++GO:0060496///mesenchymal-epithelial cell signaling involved in lung development+++GO:0060510///type II pneumocyte differentiation+++GO:0060513///prostatic bud formation+++GO:0060541///respiratory system development+++GO:0060594///mammary gland specification+++GO:0060595///fibroblast growth factor receptor signaling pathway involved in mammary gland specification+++GO:0060615///mammary gland bud formation+++GO:0060661///submandibular salivary gland formation+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0060667///branch elongation involved in salivary gland morphogenesis+++GO:0060879///semicircular canal fusion+++GO:0060915///mesenchymal cell differentiation involved in lung development+++GO:0061033///secretion by lung epithelial cell involved in lung growth+++GO:0061115///lung proximal/distal axis specification+++GO:0070075///tear secretion+++GO:0070352///positive regulation of white fat cell proliferation+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070384///Harderian gland development+++GO:0071338///positive regulation of hair follicle cell proliferation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 14166 14166 'Fgf11' mRNA 174 193 161 2.35 2.6 2.32 2.41 2.5 2.62 2.423333333 2.51 204 209 217 176 210 0.22247514 0.245765748 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008083///growth factor activity+++GO:0017080///sodium channel regulator activity GO:0007165///signal transduction+++GO:1905150///regulation of voltage-gated sodium channel activity 14167 14167 'Fgf12' mRNA 142 119 107 1.47 1.23 1.22 0.15 0.11 0.13 1.306666667 0.13 14 10 11 122.6666667 11.66666667 2.22E-20 -3.404352858 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045202///synapse GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0017080///sodium channel regulator activity+++GO:0044325///ion channel binding GO:0003254///regulation of membrane depolarization+++GO:0007254///JNK cascade+++GO:0007268///chemical synaptic transmission+++GO:0008344///adult locomotory behavior+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010765///positive regulation of sodium ion transport+++GO:0050905///neuromuscular process+++GO:0098908///regulation of neuronal action potential+++GO:1902305///regulation of sodium ion transmembrane transport+++GO:1905150///regulation of voltage-gated sodium channel activity+++GO:2000649///regulation of sodium ion transmembrane transporter activity+++GO:2001258///negative regulation of cation channel activity 14168 14168 'Fgf13' mRNA 79 86 63.94 1.63 1.84 1.43 1.07 1.11 1.46 1.633333333 1.213333333 49.24 58 74.82 76.31333333 60.68666667 0.351292175 -0.337832782 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016328///lateral plasma membrane+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0008017///microtubule binding+++GO:0008083///growth factor activity+++GO:0017080///sodium channel regulator activity+++GO:0030295///protein kinase activator activity+++GO:0044325///ion channel binding+++GO:0048487///beta-tubulin binding GO:0000165///MAPK cascade+++GO:0001764///neuron migration+++GO:0006814///sodium ion transport+++GO:0006915///apoptotic process+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007612///learning+++GO:0007613///memory+++GO:0021766///hippocampus development+++GO:0021795///cerebral cortex cell migration+++GO:0032147///activation of protein kinase activity+++GO:0045200///establishment of neuroblast polarity+++GO:0046785///microtubule polymerization+++GO:0048671///negative regulation of collateral sprouting+++GO:0072659///protein localization to plasma membrane+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:1904862///inhibitory synapse assembly+++GO:1905150///regulation of voltage-gated sodium channel activity+++GO:1990834///response to odorant 14169 14169 'Fgf14' mRNA 1444.75 1472.24 1228.25 9.38 9.43 8.15 5.1 5.06 5.36 8.986666667 5.173333333 882.86 817.22 870.86 1381.746667 856.98 2.35E-16 -0.698890649 05017///Spinocerebellar ataxia GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045202///synapse GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0017080///sodium channel regulator activity GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0007268///chemical synaptic transmission+++GO:0007399///nervous system development+++GO:0008344///adult locomotory behavior+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010765///positive regulation of sodium ion transport+++GO:0048167///regulation of synaptic plasticity+++GO:0050905///neuromuscular process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1901843///positive regulation of high voltage-gated calcium channel activity+++GO:1903421///regulation of synaptic vesicle recycling+++GO:1905150///regulation of voltage-gated sodium channel activity 14171 14171 'Fgf17' mRNA 7 2 3 0.2 0.07 0.16 0.05 0.1 0.03 0.143333333 0.06 2 4 1 4 2.333333333 0.66593265 -0.781026258 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration 14172 14172 'Fgf18' mRNA 8 10 6 0.3 0.38 0.24 0.4 0.44 0.31 0.306666667 0.383333333 12 13 9 8 11.33333333 0.613640626 0.498185832 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001957///intramembranous ossification+++GO:0001958///endochondral ossification+++GO:0002063///chondrocyte development+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000546///positive regulation of endothelial cell chemotaxis to fibroblast growth factor 14173 14173 'Fgf2' mRNA 194.86 202.68 198.99 2.2 1.89 2.17 1.72 1.27 2.16 2.086666667 1.716666667 213.22 131.52 218.6 198.8433333 187.78 0.743984844 -0.095291346 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0005125///cytokine activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0019956///chemokine binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0090722///receptor-receptor interaction "GO:0000186///activation of MAPKK activity+++GO:0001525///angiogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001759///organ induction+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0009887///animal organ morphogenesis+++GO:0010001///glial cell differentiation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010764///negative regulation of fibroblast migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014843///growth factor dependent regulation of skeletal muscle satellite cell proliferation+++GO:0021762///substantia nigra development+++GO:0021940///positive regulation of cerebellar granule cell precursor proliferation+++GO:0030154///cell differentiation+++GO:0030214///hyaluronan catabolic process+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0032958///inositol phosphate biosynthetic process+++GO:0038001///paracrine signaling+++GO:0042060///wound healing+++GO:0042660///positive regulation of cell fate specification+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045597///positive regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046668///regulation of retinal cell programmed cell death+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048678///response to axon injury+++GO:0048864///stem cell development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050918///positive chemotaxis+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060038///cardiac muscle cell proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060128///corticotropin hormone secreting cell differentiation+++GO:0060129///thyroid-stimulating hormone-secreting cell differentiation+++GO:0060548///negative regulation of cell death+++GO:0060591///chondroblast differentiation+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0061045///negative regulation of wound healing+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905278///positive regulation of epithelial tube formation+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000544///regulation of endothelial cell chemotaxis to fibroblast growth factor+++GO:2000546///positive regulation of endothelial cell chemotaxis to fibroblast growth factor+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2001028///positive regulation of endothelial cell chemotaxis" 14174 14174 'Fgf3' mRNA 45 54 70 2.32 2.75 3.82 0.67 0.69 0.37 2.963333333 0.576666667 15 15 8 56.33333333 12.66666667 4.34E-06 -2.174158613 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001759///organ induction+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030916///otic vesicle formation+++GO:0036342///post-anal tail morphogenesis+++GO:0048538///thymus development+++GO:0048752///semicircular canal morphogenesis+++GO:0051781///positive regulation of cell division+++GO:0055026///negative regulation of cardiac muscle tissue development 14175 14175 'Fgf4' mRNA 81 48 71 1.47 0.86 1.36 0.3 0.58 0.57 1.23 0.483333333 19 36 35 66.66666667 30 0.004913663 -1.163642867 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001502///cartilage condensation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010463///mesenchymal cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030334///regulation of cell migration+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051781///positive regulation of cell division+++GO:0060363///cranial suture morphogenesis+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0060591///chondroblast differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000544///regulation of endothelial cell chemotaxis to fibroblast growth factor 14176 14176 'Fgf5' mRNA 64 78 71 1.45 1.74 1.7 0.17 0.4 0.18 1.63 0.25 9 20 9 71 12.66666667 1.49E-08 -2.494751957 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010001///glial cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0051781///positive regulation of cell division 14177 14177 'Fgf6' mRNA 0 0 1 0 0 0.05 0 0 0.04 0.016666667 0.013333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0042383///sarcolemma GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001502///cartilage condensation+++GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0045445///myoblast differentiation+++GO:0051781///positive regulation of cell division 14178 14178 'Fgf7' mRNA 170 159 164 3.53 3.25 3.61 3.32 3.16 2.83 3.463333333 3.103333333 184 171 152 164.3333333 169 0.916121458 0.027179265 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0005104///fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0042056///chemoattractant activity "GO:0001541///ovarian follicle development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0010463///mesenchymal cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0031069///hair follicle morphogenesis+++GO:0031532///actin cytoskeleton reorganization+++GO:0034394///protein localization to cell surface+++GO:0042060///wound healing+++GO:0043129///surfactant homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051781///positive regulation of cell division+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0061033///secretion by lung epithelial cell involved in lung growth" 14179 14179 'Fgf8' mRNA 19 28 19 0.95 1.38 1 0.06 0 0.06 1.11 0.04 2 0 1 22 1 5.88E-05 -4.470472584 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009897///external side of plasma membrane GO:0005104///fibroblast growth factor receptor binding+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity GO:0000165///MAPK cascade+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001759///organ induction+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0001839///neural plate morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001947///heart looping+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0006979///response to oxidative stress+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0008045///motor neuron axon guidance+++GO:0008078///mesodermal cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0008406///gonad development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0009887///animal organ morphogenesis+++GO:0009953///dorsal/ventral pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0021537///telencephalon development+++GO:0021543///pallium development+++GO:0021544///subpallium development+++GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0021846///cell proliferation in forebrain+++GO:0021884///forebrain neuron development+++GO:0021954///central nervous system neuron development+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0030539///male genitalia development+++GO:0030878///thyroid gland development+++GO:0030916///otic vesicle formation+++GO:0030917///midbrain-hindbrain boundary development+++GO:0033563///dorsal/ventral axon guidance+++GO:0035050///embryonic heart tube development+++GO:0035108///limb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035909///aorta morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042476///odontogenesis+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045165///cell fate commitment+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0046622///positive regulation of organ growth+++GO:0048699///generation of neurons+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048853///forebrain morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0055026///negative regulation of cardiac muscle tissue development+++GO:0060037///pharyngeal system development+++GO:0060128///corticotropin hormone secreting cell differentiation+++GO:0060129///thyroid-stimulating hormone-secreting cell differentiation+++GO:0060348///bone development+++GO:0060425///lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060563///neuroepithelial cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071542///dopaminergic neuron differentiation+++GO:0090134///cell migration involved in mesendoderm migration 14180 14180 'Fgf9' mRNA 81 81 61 1.06 1.04 0.85 0.94 0.68 0.92 0.983333333 0.846666667 83 60 79 74.33333333 74 0.97292398 -0.015382454 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001649///osteoblast differentiation+++GO:0001654///eye development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003231///cardiac ventricle development+++GO:0006606///protein import into nucleus+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008584///male gonad development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030238///male sex determination+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030334///regulation of cell migration+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0042472///inner ear morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048505///regulation of timing of cell differentiation+++GO:0048566///embryonic digestive tract development+++GO:0048706///embryonic skeletal system development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051781///positive regulation of cell division+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060484///lung-associated mesenchyme development+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1905931///negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching" 14181 14181 'Fgfbp1' mRNA 93 121 109 4.77 6.09 5.89 28.41 27.43 29.37 5.583333333 28.40333333 647 610 643 107.6666667 633.3333333 8.62E-67 2.544549329 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane GO:0017134///fibroblast growth factor binding+++GO:0019838///growth factor binding GO:0007267///cell-cell signaling+++GO:0008284///positive regulation of cell proliferation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 14182 14182 'Fgfr1' mRNA 4806 4967 2516 52.05 52.81 29.33 28.62 30.6 31.23 44.73 30.15 2990 3141 3188 4096.333333 3106.333333 0.217886658 -0.395228087 "04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04714///Thermogenesis+++04810///Regulation of actin cytoskeleton+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05215///Prostate cancer+++05218///Melanoma+++05224///Breast cancer+++05230///Central carbon metabolism in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008201///heparin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017134///fibroblast growth factor binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding+++GO:0090722///receptor-receptor interaction GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001759///organ induction+++GO:0001837///epithelial to mesenchymal transition+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007435///salivary gland morphogenesis+++GO:0007605///sensory perception of sound+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010763///positive regulation of fibroblast migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0010966///regulation of phosphate transport+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019827///stem cell population maintenance+++GO:0021769///orbitofrontal cortex development+++GO:0021837///motogenic signaling involved in postnatal olfactory bulb interneuron migration+++GO:0021847///ventricular zone neuroblast division+++GO:0021954///central nervous system neuron development+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030901///midbrain development+++GO:0031175///neuron projection development+++GO:0033674///positive regulation of kinase activity+++GO:0035607///fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development+++GO:0042127///regulation of cell proliferation+++GO:0042472///inner ear morphogenesis+++GO:0042473///outer ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043583///ear development+++GO:0045597///positive regulation of cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048339///paraxial mesoderm development+++GO:0048378///regulation of lateral mesodermal cell fate specification+++GO:0048469///cell maturation+++GO:0048514///blood vessel morphogenesis+++GO:0048699///generation of neurons+++GO:0048762///mesenchymal cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0051174///regulation of phosphorus metabolic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051930///regulation of sensory perception of pain+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060117///auditory receptor cell development+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060484///lung-associated mesenchyme development+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0070640///vitamin D3 metabolic process+++GO:0072091///regulation of stem cell proliferation+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway+++GO:0090272///negative regulation of fibroblast growth factor production+++GO:1903465///positive regulation of mitotic cell cycle DNA replication+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000491///positive regulation of hepatic stellate cell activation+++GO:2000546///positive regulation of endothelial cell chemotaxis to fibroblast growth factor+++GO:2000830///positive regulation of parathyroid hormone secretion+++GO:2001239///regulation of extrinsic apoptotic signaling pathway in absence of ligand 14183 14183 'Fgfr2' mRNA 1238 1257 865 13.34 13.3 9.94 7.74 7.59 7.79 12.19333333 7.706666667 823 795 809 1120 809 4.27E-05 -0.473685915 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05215///Prostate cancer+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043235///receptor complex+++GO:0060076///excitatory synapse+++GO:0062023///collagen-containing extracellular matrix GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008201///heparin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017134///fibroblast growth factor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003148///outflow tract septum morphogenesis+++GO:0003149///membranous septum morphogenesis+++GO:0003416///endochondral bone growth+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007528///neuromuscular junction development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009791///post-embryonic development+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0010518///positive regulation of phospholipase activity+++GO:0010628///positive regulation of gene expression+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016310///phosphorylation+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021769///orbitofrontal cortex development+++GO:0021847///ventricular zone neuroblast division+++GO:0021860///pyramidal neuron development+++GO:0022612///gland morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030282///bone mineralization+++GO:0030324///lung development+++GO:0030855///epithelial cell differentiation+++GO:0030901///midbrain development+++GO:0030916///otic vesicle formation+++GO:0031069///hair follicle morphogenesis+++GO:0032496///response to lipopolysaccharide+++GO:0032808///lacrimal gland development+++GO:0033674///positive regulation of kinase activity+++GO:0035265///organ growth+++GO:0035602///fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow+++GO:0035603///fibroblast growth factor receptor signaling pathway involved in hemopoiesis+++GO:0035604///fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow+++GO:0035607///fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042472///inner ear morphogenesis+++GO:0042476///odontogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0045471///response to ethanol+++GO:0045787///positive regulation of cell cycle+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048286///lung alveolus development+++GO:0048333///mesodermal cell differentiation+++GO:0048489///synaptic vesicle transport+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048562///embryonic organ morphogenesis+++GO:0048565///digestive tract development+++GO:0048568///embryonic organ development+++GO:0048608///reproductive structure development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048730///epidermis morphogenesis+++GO:0048755///branching morphogenesis of a nerve+++GO:0048762///mesenchymal cell differentiation+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:0051781///positive regulation of cell division+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060174///limb bud formation+++GO:0060348///bone development+++GO:0060349///bone morphogenesis+++GO:0060365///coronal suture morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060449///bud elongation involved in lung branching+++GO:0060463///lung lobe morphogenesis+++GO:0060484///lung-associated mesenchyme development+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060512///prostate gland morphogenesis+++GO:0060523///prostate epithelial cord elongation+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0060529///squamous basal epithelial stem cell differentiation involved in prostate gland acinus development+++GO:0060595///fibroblast growth factor receptor signaling pathway involved in mammary gland specification+++GO:0060601///lateral sprouting from an epithelium+++GO:0060615///mammary gland bud formation+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0060667///branch elongation involved in salivary gland morphogenesis+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060688///regulation of morphogenesis of a branching structure+++GO:0060915///mesenchymal cell differentiation involved in lung development+++GO:0060916///mesenchymal cell proliferation involved in lung development+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0061031///endodermal digestive tract morphogenesis+++GO:0070307///lens fiber cell development+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway 14184 14184 'Fgfr3' mRNA 69 101 84 0.94 1.31 1.17 0.56 0.58 0.45 1.14 0.53 48 48 39 84.66666667 45 0.004781583 -0.923230228 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05219///Bladder cancer+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017134///fibroblast growth factor binding+++GO:0042802///identical protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002009///morphogenesis of an epithelium+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010518///positive regulation of phospholipase activity+++GO:0010629///negative regulation of gene expression+++GO:0010712///regulation of collagen metabolic process+++GO:0014003///oligodendrocyte development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021762///substantia nigra development+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0030278///regulation of ossification+++GO:0030282///bone mineralization+++GO:0030501///positive regulation of bone mineralization+++GO:0030900///forebrain development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0033674///positive regulation of kinase activity+++GO:0035019///somatic stem cell population maintenance+++GO:0036342///post-anal tail morphogenesis+++GO:0038066///p38MAPK cascade+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043410///positive regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045596///negative regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0046850///regulation of bone remodeling+++GO:0048546///digestive tract morphogenesis+++GO:0048640///negative regulation of developmental growth+++GO:0048678///response to axon injury+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048839///inner ear development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051216///cartilage development+++GO:0060113///inner ear receptor cell differentiation+++GO:0060348///bone development+++GO:0060349///bone morphogenesis+++GO:0060385///axonogenesis involved in innervation+++GO:0061144///alveolar secondary septum development+++GO:0061430///bone trabecula morphogenesis+++GO:0070307///lens fiber cell development+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070977///bone maturation+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0072148///epithelial cell fate commitment+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway+++GO:0090102///cochlea development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902178///fibroblast growth factor receptor apoptotic signaling pathway 14186 14186 'Fgfr4' mRNA 635 775 633 11.12 13.43 11.76 7.55 6.74 6.5 12.10333333 6.93 497 425 416 681 446 3.49E-07 -0.621460268 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008201///heparin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017134///fibroblast growth factor binding GO:0001759///organ induction+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0010966///regulation of phosphate transport+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019216///regulation of lipid metabolic process+++GO:0030324///lung development+++GO:0033674///positive regulation of kinase activity+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0043085///positive regulation of catalytic activity+++GO:0045862///positive regulation of proteolysis+++GO:0046777///protein autophosphorylation+++GO:0051174///regulation of phosphorus metabolic process+++GO:0055062///phosphate ion homeostasis+++GO:0061144///alveolar secondary septum development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070640///vitamin D3 metabolic process+++GO:0070857///regulation of bile acid biosynthetic process+++GO:0090272///negative regulation of fibroblast growth factor production+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000830///positive regulation of parathyroid hormone secretion 14187 14187 'Akr1b8' mRNA 74 51 58 3.36 2.28 2.79 18.8 17.57 15.03 2.81 17.13333333 476 434 368 61 426 6.13E-47 2.79135323 00040///Pentose and glucuronate interconversions+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00561///Glycerolipid metabolism+++00790///Folate biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0045550///geranylgeranyl reductase activity+++GO:0047718///indanol dehydrogenase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0052650///NADP-retinol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0016488///farnesol catabolic process+++GO:0042572///retinol metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0110095///cellular detoxification of aldehyde 14190 14190 'Fgl2' mRNA 148 188 162 2.13 2.66 2.47 9.04 8.43 7.77 2.42 8.413333333 724 660 603 166 662.3333333 5.49E-46 1.984522383 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0008233///peptidase activity GO:0002291///T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002605///negative regulation of dendritic cell antigen processing and presentation+++GO:0002617///negative regulation of macrophage antigen processing and presentation+++GO:0006508///proteolysis+++GO:0019835///cytolysis+++GO:0043381///negative regulation of memory T cell differentiation+++GO:0050687///negative regulation of defense response to virus 14191 14191 'Fgr' mRNA 23 24 28 0.44 0.46 0.59 5.91 6.09 6.41 0.496666667 6.136666667 359 335 353 25 349 7.97E-59 3.790125899 04062///Chemokine signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0034987///immunoglobulin receptor binding+++GO:0034988///Fc-gamma receptor I complex binding GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008360///regulation of cell shape+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030335///positive regulation of cell migration+++GO:0032815///negative regulation of natural killer cell activation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045859///regulation of protein kinase activity+++GO:0046777///protein autophosphorylation+++GO:0048705///skeletal system morphogenesis+++GO:0050764///regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium 14194 14194 'Fh1' mRNA 1655 1627 1649 59.2 57.38 62.58 63.13 61.47 65.12 59.72 63.24 2028 1927 2024 1643.666667 1993 5.19E-04 0.265099301 00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++04934///Cushing syndrome+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0035861///site of double-strand break+++GO:0045239///tricarboxylic acid cycle enzyme complex GO:0003824///catalytic activity+++GO:0004333///fumarate hydratase activity+++GO:0016829///lyase activity+++GO:0042393///histone binding GO:0000050///urea cycle+++GO:0000415///negative regulation of histone H3-K36 methylation+++GO:0000821///regulation of arginine metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006106///fumarate metabolic process+++GO:0006108///malate metabolic process+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 14198 14198 'Fhit' mRNA 175 162 158 12.25 11.36 11.6 1.42 1.26 1.33 11.73666667 1.336666667 23 20 21 165 21.33333333 1.42E-24 -2.963253971 00230///Purine metabolism+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0016151///nickel cation binding+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043530///adenosine 5'-monophosphoramidase activity+++GO:0047352///adenylylsulfate-ammonia adenylyltransferase activity+++GO:0047627///adenylylsulfatase activity+++GO:0047710///bis(5'-adenosyl)-triphosphatase activity GO:0006163///purine nucleotide metabolic process+++GO:0006260///DNA replication+++GO:0006915///apoptotic process+++GO:0015964///diadenosine triphosphate catabolic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 14199 14199 'Fhl1' mRNA 208 229 207 4.9 5.33 5.1 3.75 3.75 4.4 5.11 3.966666667 180 180 211 214.6666667 190.3333333 0.382054484 -0.184124782 04630///JAK-STAT signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0003254///regulation of membrane depolarization+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0043268///positive regulation of potassium ion transport+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 14200 14200 'Fhl2' mRNA 55 40 61 2.06 1.48 2.43 3.72 4.6 3.64 1.99 3.986666667 111 136 108 52 118.3333333 7.16E-05 1.170226348 04380///Osteoclast differentiation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030018///Z disc+++GO:0031430///M band GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009725///response to hormone+++GO:0043066///negative regulation of apoptotic process+++GO:0055014///atrial cardiac muscle cell development+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060347///heart trabecula formation+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 14201 14201 'Fhl3' mRNA 156 146 85 5.32 4.96 3.1 5.17 4.15 4.69 4.46 4.67 174 135 157 129 155.3333333 0.347527532 0.264530343 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030018///Z disc GO:0003712///transcription coregulator activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030036///actin cytoskeleton organization" 14202 14202 'Fhl4' mRNA 11 7 9 0.23 0.14 0.2 0.29 0.31 0.11 0.19 0.236666667 16 17 6 9 13 0.593573285 0.516257185 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0003254///regulation of membrane depolarization+++GO:0007517///muscle organ development+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0030308///negative regulation of cell growth+++GO:0043268///positive regulation of potassium ion transport+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 14204 14204 'Il4i1' mRNA 98.25 103 100 2.73 2.82 2.94 1.8 2.22 2.32 2.83 2.113333333 74.47 90 93 100.4166667 85.82333333 0.440855949 -0.238362456 "00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis" GO:0001669///acrosomal vesicle+++GO:0001772///immunological synapse+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0097225///sperm midpiece GO:0001716///L-amino-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity GO:0002250///adaptive immune response+++GO:0002819///regulation of adaptive immune response+++GO:0002841///negative regulation of T cell mediated immune response to tumor cell+++GO:0006559///L-phenylalanine catabolic process+++GO:0006569///tryptophan catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0009063///cellular amino acid catabolic process+++GO:0009072///aromatic amino acid family metabolic process+++GO:0019440///tryptophan catabolic process to indole-3-acetate+++GO:0042130///negative regulation of T cell proliferation+++GO:0045577///regulation of B cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050868///negative regulation of T cell activation 14205 14205 'Vegfd' mRNA 12 8 15 0.45 0.32 0.64 1.36 1.14 0.78 0.47 1.093333333 38 31 22 11.66666667 30.33333333 0.022431032 1.355659975 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04668///TNF signaling pathway+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0043185///vascular endothelial growth factor receptor 3 binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0030154///cell differentiation+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032755///positive regulation of interleukin-6 production+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0071542///dopaminergic neuron differentiation 14208 14208 'Ppm1g' mRNA 1316 1434 1423 34.32 36.83 39.37 44.73 46.28 45.13 36.84 45.38 1972 1992 1926 1391 1963.333333 2.06E-09 0.484314733 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0051726///regulation of cell cycle 14211 14211 'Smc2' mRNA 158 165 167 1.52 1.56 1.7 5.81 5.26 5.83 1.593333333 5.633333333 693 613 674 163.3333333 660 1.93E-51 2.001446908 GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0000012///single strand break repair+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0045132///meiotic chromosome segregation+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051383///kinetochore organization 14218 14218 'Sh3pxd2a' mRNA 449 462 348 2.39 2.42 2.01 2.4 2.11 2.22 2.273333333 2.243333333 500 428 449 419.6666667 459 0.448501093 0.121226556 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042995///cell projection "GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0060090///molecular adaptor activity+++GO:0070273///phosphatidylinositol-4-phosphate binding" GO:0001701///in utero embryonic development+++GO:0006801///superoxide metabolic process+++GO:0042554///superoxide anion generation+++GO:0050790///regulation of catalytic activity+++GO:0072593///reactive oxygen species metabolic process+++GO:0072675///osteoclast fusion 14219 14219 'Ccn2' mRNA 936 837 1035 21.78 19.17 25.54 61.37 49.49 56.81 22.16333333 55.89 3034 2389 2719 936 2714 2.74E-48 1.517076424 04371///Apelin signaling pathway+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0031012///extracellular matrix+++GO:0048471///perinuclear region of cytoplasm GO:0001968///fibronectin binding+++GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008022///protein C-terminus binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001894///tissue homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0007229///integrin-mediated signaling pathway+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009749///response to glucose+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0032330///regulation of chondrocyte differentiation+++GO:0032355///response to estradiol+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0034059///response to anoxia+++GO:0035556///intracellular signal transduction+++GO:0035988///chondrocyte proliferation+++GO:0043200///response to amino acid+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045597///positive regulation of cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0050867///positive regulation of cell activation+++GO:0051385///response to mineralocorticoid+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060401///cytosolic calcium ion transport+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0060548///negative regulation of cell death+++GO:0061448///connective tissue development+++GO:0070278///extracellular matrix constituent secretion+++GO:0070318///positive regulation of G0 to G1 transition+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070542///response to fatty acid+++GO:0071897///DNA biosynthetic process+++GO:0072593///reactive oxygen species metabolic process 14221 14221 'Fjx1' mRNA 9 17 13 0.21 0.39 0.32 0.66 1.07 0.87 0.306666667 0.866666667 33 52 42 13 42.33333333 9.56E-04 1.696590104 04391///Hippo signaling pathway - fly GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0007267///cell-cell signaling+++GO:0010842///retina layer formation 14225 14225 'Fkbp1a' mRNA 4213 4342 4302 147.79 150.23 160.2 278.37 264.41 273.08 152.74 271.9533333 9117 8449 8655 4285.666667 8740.333333 1.15E-71 1.014873498 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0031312///extrinsic component of organelle membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0098562///cytoplasmic side of membrane+++GO:1990425///ryanodine receptor complex GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding+++GO:0030544///Hsp70 protein binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046332///SMAD binding+++GO:0048185///activin binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0003007///heart morphogenesis+++GO:0006936///muscle contraction+++GO:0007183///SMAD protein complex assembly+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031000///response to caffeine+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032092///positive regulation of protein binding+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032880///regulation of protein localization+++GO:0032925///regulation of activin receptor signaling pathway+++GO:0042098///T cell proliferation+++GO:0050776///regulation of immune response+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060347///heart trabecula formation+++GO:0061077///chaperone-mediated protein folding+++GO:0097435///supramolecular fiber organization+++GO:1901393///negative regulation of transforming growth factor beta1 activation+++GO:1902991///regulation of amyloid precursor protein catabolic process+++GO:1990000///amyloid fibril formation 14226 14226 'Fkbp1b' mRNA 71 68 66 4.78 4.52 4.66 7.99 11.15 9.12 4.653333333 9.42 136 186 150 68.33333333 157.3333333 1.46E-06 1.194530562 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034704///calcium channel complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0019855///calcium channel inhibitor activity+++GO:0030551///cyclic nucleotide binding+++GO:0044325///ion channel binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0002027///regulation of heart rate+++GO:0006939///smooth muscle contraction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009749///response to glucose+++GO:0010033///response to organic substance+++GO:0010459///negative regulation of heart rate+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0019227///neuronal action potential propagation+++GO:0030073///insulin secretion+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0033197///response to vitamin E+++GO:0042098///T cell proliferation+++GO:0042542///response to hydrogen peroxide+++GO:0048680///positive regulation of axon regeneration+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051775///response to redox state+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0061077///chaperone-mediated protein folding+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 14227 14227 'Fkbp2' mRNA 2064.56 1906.28 1889.57 237.1 217.79 231.09 300.06 362.94 305.98 228.66 322.9933333 2982 3489.42 2914.24 1953.47 3128.553333 6.18E-15 0.669473907 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0061077///chaperone-mediated protein folding 14228 14228 'Fkbp4' mRNA 7795 8015 7581 200.14 202.68 206.49 117.49 121.37 119.28 203.1033333 119.38 5262 5307 5171 7797 5246.666667 6.41E-28 -0.582909653 04915///Estrogen signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0031072///heat shock protein binding+++GO:0032767///copper-dependent protein binding+++GO:0035259///glucocorticoid receptor binding+++GO:0048156///tau protein binding+++GO:0051219///phosphoprotein binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006463///steroid hormone receptor complex assembly+++GO:0006825///copper ion transport+++GO:0007566///embryo implantation+++GO:0010977///negative regulation of neuron projection development+++GO:0030521///androgen receptor signaling pathway+++GO:0030850///prostate gland development+++GO:0031111///negative regulation of microtubule polymerization or depolymerization+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031503///protein-containing complex localization+++GO:0046661///male sex differentiation+++GO:0048608///reproductive structure development+++GO:0061077///chaperone-mediated protein folding 14229 14229 'Fkbp5' mRNA 130 146 121 1.81 2 1.79 5.53 4.59 5.82 1.866666667 5.313333333 457 371 466 132.3333333 431.3333333 6.88E-26 1.693745891 04915///Estrogen signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0031072///heat shock protein binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0009617///response to bacterium+++GO:0061077///chaperone-mediated protein folding 14230 14230 'Fkbp10' mRNA 1826.63 1838.64 1799.67 38.97 38.61 40.72 43.02 45.57 42.9 39.43333333 43.83 2319.79 2399.73 2239.76 1821.646667 2319.76 4.37E-06 0.337022547 GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001701///in utero embryonic development+++GO:0006457///protein folding+++GO:0007283///spermatogenesis+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0018208///peptidyl-proline modification+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0035909///aorta morphogenesis+++GO:0042060///wound healing+++GO:0043046///DNA methylation involved in gamete generation+++GO:0045070///positive regulation of viral genome replication+++GO:0051321///meiotic cell cycle+++GO:0085029///extracellular matrix assembly 14231 14231 'Fkbp7' mRNA 443 507 485 32.21 36.19 37.3 79.33 80.54 73.58 35.23333333 77.81666667 1245 1231 1118 478.3333333 1198 2.15E-38 1.312040362 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0000413///protein peptidyl-prolyl isomerization 14232 14232 'Fkbp8' mRNA 3358 3328 2684 112.41 109.38 94.35 87.36 93.33 93.18 105.38 91.29 2997 3132 3100 3123.333333 3076.333333 0.780607592 -0.028731181 GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0097718///disordered domain specific binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001708///cell fate specification+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0007224///smoothened signaling pathway+++GO:0009953///dorsal/ventral pattern formation+++GO:0010468///regulation of gene expression+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021915///neural tube development+++GO:0030510///regulation of BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process 14233 14233 'Foxi1' mRNA 4 2 2 0.1 0.05 0.05 0 0.02 0.06 0.066666667 0.026666667 0 1 3 2.666666667 1.333333333 0.665850874 -0.998185654 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0042472///inner ear morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 14234 14234 'Foxc2' mRNA 48 66 14 0.97 1.32 0.3 0.62 1.86 1.64 0.863333333 1.373333333 35 103 90 42.66666667 76 0.105458875 0.854289932 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001568///blood vessel development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001756///somitogenesis+++GO:0001822///kidney development+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0009653///anatomical structure morphogenesis+++GO:0009725///response to hormone+++GO:0010595///positive regulation of endothelial cell migration+++GO:0014032///neural crest cell development+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0033625///positive regulation of integrin activation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035050///embryonic heart tube development+++GO:0035470///positive regulation of vascular wound healing+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046620///regulation of organ growth+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048341///paraxial mesoderm formation+++GO:0048343///paraxial mesodermal cell fate commitment+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048844///artery morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060038///cardiac muscle cell proliferation+++GO:0072011///glomerular endothelium development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0072144///glomerular mesangial cell development+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0097746///regulation of blood vessel diameter+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1902257///negative regulation of apoptotic process involved in outflow tract morphogenesis" 14235 14235 'Foxm1' mRNA 55 72 56 0.68 0.87 0.73 2.21 1.55 1.86 0.76 1.873333333 207 142 168 61 172.3333333 2.11E-09 1.485890377 04218///Cellular senescence GO:0005634///nucleus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0043565///sequence-specific DNA binding "GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000302///response to reactive oxygen species+++GO:0001570///vasculogenesis+++GO:0001889///liver development+++GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046578///regulation of Ras protein signal transduction+++GO:0051726///regulation of cell cycle+++GO:0071156///regulation of cell cycle arrest+++GO:0090344///negative regulation of cell aging+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000781///positive regulation of double-strand break repair" 14236 14236 'Foxn2' mRNA 388.44 433.4 437.99 4.51 4.98 4.75 6.37 5.26 6.56 4.746666667 6.063333333 596.01 468.06 560.95 419.9433333 541.6733333 0.011128857 0.353148612 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001942///hair follicle development+++GO:0002260///lymphocyte homeostasis+++GO:0002360///T cell lineage commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008544///epidermis development+++GO:0010468///regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0035878///nail development+++GO:0035914///skeletal muscle cell differentiation+++GO:0043029///T cell homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0048538///thymus development+++GO:0051798///positive regulation of hair follicle development+++GO:0097535///lymphoid lineage cell migration into thymus+++GO:0097536///thymus epithelium morphogenesis+++GO:1902232///regulation of positive thymic T cell selection" 14238 14238 'Foxf2' mRNA 65 71 38 1.54 1.65 0.95 1.05 0.82 0.64 1.38 0.836666667 51 39 30 58 40 0.206567304 -0.539679415 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009887///animal organ morphogenesis+++GO:0030198///extracellular matrix organization+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0042249///establishment of planar polarity of embryonic epithelium+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048566///embryonic digestive tract development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048806///genitalia development+++GO:0060021///roof of mouth development+++GO:1902914///regulation of protein polyubiquitination" 14239 14239 'Foxs1' mRNA 25 18 18 1.15 0.82 0.88 0.68 0.49 0.5 0.95 0.556666667 17 12 12 20.33333333 13.66666667 0.400891025 -0.58573301 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0040018///positive regulation of multicellular organism growth+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050885///neuromuscular process controlling balance" 14241 14241 'Foxl1' mRNA 2 0 5 0.04 0 0.1 0.15 0.1 0.17 0.046666667 0.14 9 6 10 2.333333333 8.333333333 0.17018182 1.792793136 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007495///visceral mesoderm-endoderm interaction involved in midgut development+++GO:0007507///heart development+++GO:0009653///anatomical structure morphogenesis+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030166///proteoglycan biosynthetic process+++GO:0061146///Peyer's patch morphogenesis" 14245 14245 'Lpin1' mRNA 1124 1120 991 11.06 10.94 10.43 6.2 6.04 6.43 10.81 6.223333333 726 686 728 1078.333333 713.3333333 1.49E-11 -0.606197373 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04150///mTOR signaling pathway+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0001085///RNA polymerase II transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042826///histone deacetylase binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000266///mitochondrial fission+++GO:0006260///DNA replication+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006642///triglyceride mobilization+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0006955///immune response+++GO:0009062///fatty acid catabolic process+++GO:0016311///dephosphorylation+++GO:0019432///triglyceride biosynthetic process+++GO:0031065///positive regulation of histone deacetylation+++GO:0031100///animal organ regeneration+++GO:0031529///ruffle organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0031642///negative regulation of myelination+++GO:0032869///cellular response to insulin stimulus+++GO:0044255///cellular lipid metabolic process+++GO:0045444///fat cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046473///phosphatidic acid metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903730///regulation of phosphatidate phosphatase activity+++GO:1903741///negative regulation of phosphatidate phosphatase activity" 14247 14247 'Fli1' mRNA 302 285 276 5.07 4.76 4.88 16.92 15 16.58 4.903333333 16.16666667 1137 986 1083 287.6666667 1068.666667 7.91E-70 1.881168888 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008015///blood circulation+++GO:0009887///animal organ morphogenesis+++GO:0009987///cellular process+++GO:0030154///cell differentiation+++GO:0035855///megakaryocyte development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 14248 14248 'Flii' mRNA 2596 2766 2890 34.49 36.15 40.73 36.91 35.95 35.46 37.12333333 36.10666667 3197 3042 2975 2750.666667 3071.333333 0.086450648 0.144310825 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0034451///centriolar satellite "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding" GO:0007275///multicellular organism development+++GO:0008154///actin polymerization or depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030239///myofibril assembly+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping 14251 14251 'Flot1' mRNA 1346 1285 1133 46.28 43.62 41.39 88.18 84.16 84.63 43.76333333 85.65666667 2947 2741 2737 1254.666667 2808.333333 1.55E-60 1.152396529 04910///Insulin signaling pathway GO:0001931///uropod+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0008180///COP9 signalosome+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030864///cortical actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0034451///centriolar satellite+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0044291///cell-cell contact zone+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0098691///dopaminergic synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0035255///ionotropic glutamate receptor binding "GO:0001765///membrane raft assembly+++GO:0001819///positive regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002090///regulation of receptor internalization+++GO:0006897///endocytosis+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0022617///extracellular matrix disassembly+++GO:0032092///positive regulation of protein binding+++GO:0032226///positive regulation of synaptic transmission, dopaminergic+++GO:0032728///positive regulation of interferon-beta production+++GO:0033227///dsRNA transport+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035023///regulation of Rho protein signal transduction+++GO:0044854///plasma membrane raft assembly+++GO:0045807///positive regulation of endocytosis+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0050821///protein stabilization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051580///regulation of neurotransmitter uptake+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0070528///protein kinase C signaling+++GO:0071360///cellular response to exogenous dsRNA+++GO:0072659///protein localization to plasma membrane+++GO:1901741///positive regulation of myoblast fusion+++GO:1901890///positive regulation of cell junction assembly+++GO:1903044///protein localization to membrane raft+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin" 14252 14252 'Flot2' mRNA 1515 1497 1230 30.76 30.24 26.76 29.87 31.73 31.95 29.25333333 31.18333333 1659 1718 1726 1414 1701 0.002405856 0.259036353 04910///Insulin signaling pathway GO:0001931///uropod+++GO:0002080///acrosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030139///endocytic vesicle+++GO:0030864///cortical actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032839///dendrite cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099029///anchored component of presynaptic active zone membrane GO:0002020///protease binding+++GO:0035255///ionotropic glutamate receptor binding GO:0001765///membrane raft assembly+++GO:0007155///cell adhesion+++GO:0010629///negative regulation of gene expression+++GO:0044860///protein localization to plasma membrane raft+++GO:0045661///regulation of myoblast differentiation+++GO:0050821///protein stabilization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0072659///protein localization to plasma membrane+++GO:0098937///anterograde dendritic transport+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1902992///negative regulation of amyloid precursor protein catabolic process+++GO:1903905///positive regulation of establishment of T cell polarity 14254 14254 'Flt1' mRNA 1131 1186 937 11.04 10.56 9.03 5.55 6.21 6.37 10.21 6.043333333 742 784 797 1084.666667 774.3333333 5.97E-07 -0.493211748 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++05202///Transcriptional misregulation in cancer+++05323///Rheumatoid arthritis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0036332///placental growth factor-activated receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0002040///sprouting angiogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002548///monocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006935///chemotaxis+++GO:0006940///regulation of smooth muscle contraction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0010863///positive regulation of phospholipase C activity+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030522///intracellular receptor signaling pathway+++GO:0033674///positive regulation of kinase activity+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036323///vascular endothelial growth factor receptor-1 signaling pathway+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0060252///positive regulation of glial cell proliferation+++GO:1901534///positive regulation of hematopoietic progenitor cell differentiation+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1904046///negative regulation of vascular endothelial growth factor production+++GO:1905563///negative regulation of vascular endothelial cell proliferation+++GO:1990384///hyaloid vascular plexus regression 14255 14255 'Flt3' mRNA 1 3 6 0.01 0.04 0.09 0.44 0.54 0.49 0.046666667 0.49 34 41 37.05 3.333333333 37.35 7.77E-07 3.465288358 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035259///glucocorticoid receptor binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding GO:0001776///leukocyte homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002318///myeloid progenitor cell differentiation+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0002328///pro-B cell differentiation+++GO:0002572///pro-T cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010243///response to organonitrogen compound+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019882///antigen processing and presentation+++GO:0030097///hemopoiesis+++GO:0030098///lymphocyte differentiation+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0031100///animal organ regeneration+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0033674///positive regulation of kinase activity+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0036145///dendritic cell homeostasis+++GO:0040018///positive regulation of multicellular organism growth+++GO:0045578///negative regulation of B cell differentiation+++GO:0046651///lymphocyte proliferation+++GO:0046777///protein autophosphorylation+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0071345///cellular response to cytokine stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0097028///dendritic cell differentiation+++GO:0098586///cellular response to virus 14256 14256 'Flt3l' mRNA 124 111 111 6.04 5.64 5.88 8.43 9.41 7.42 5.853333333 8.42 195 215 168 115.3333333 192.6666667 5.71E-04 0.729463967 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031233///intrinsic component of external side of plasma membrane GO:0005125///cytokine activity+++GO:0016301///kinase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0030098///lymphocyte differentiation+++GO:0030885///regulation of myeloid dendritic cell activation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0035162///embryonic hemopoiesis+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0071866///negative regulation of apoptotic process in bone marrow+++GO:0090290///positive regulation of osteoclast proliferation+++GO:1901741///positive regulation of myoblast fusion 14257 14257 'Flt4' mRNA 51 95 64 0.46 0.85 0.62 0.98 0.86 1.07 0.643333333 0.97 124 106 131 70 120.3333333 0.008499862 0.772743147 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0019903///protein phosphatase binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001944///vasculature development+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003016///respiratory system process+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007585///respiratory gaseous exchange+++GO:0008284///positive regulation of cell proliferation+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0033674///positive regulation of kinase activity+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048286///lung alveolus development+++GO:0048514///blood vessel morphogenesis+++GO:0060312///regulation of blood vessel remodeling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090037///positive regulation of protein kinase C signaling 14260 14260 'Fmn1' mRNA 2185 2070 1760 10.12 9.43 8.67 8.83 8.18 9.57 9.406666667 8.86 2175 1969 2282 2005 2142 0.370899447 0.086483969 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0017124///SH3 domain binding GO:0001822///kidney development+++GO:0010467///gene expression+++GO:0030838///positive regulation of actin filament polymerization+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0045010///actin nucleation+++GO:0048705///skeletal system morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0051127///positive regulation of actin nucleation+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060173///limb development+++GO:0072092///ureteric bud invasion 14261 14261 'Fmo1' mRNA 308.55 333.67 254.2 10.89 11.81 9.64 4.87 5.5 4.83 10.78 5.066666667 154.92 170.93 146.07 298.8066667 157.3066667 6.18E-08 -0.935854796 00982///Drug metabolism - cytochrome P450 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0006970///response to osmotic stress+++GO:0009404///toxin metabolic process+++GO:0017144///drug metabolic process+++GO:0032496///response to lipopolysaccharide+++GO:0070995///NADPH oxidation 14263 14263 'Fmo5' mRNA 324.76 277.71 292.36 5.51 4.75 5.54 3.36 3.71 4.51 5.266666667 3.86 225.5 234.28 260.31 298.2766667 240.03 0.060313463 -0.324283852 00982///Drug metabolism - cytochrome P450 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004031///aldehyde oxidase activity+++GO:0004497///monooxygenase activity+++GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0006805///xenobiotic metabolic process+++GO:0017144///drug metabolic process+++GO:0070995///NADPH oxidation+++GO:0090181///regulation of cholesterol metabolic process 14264 14264 'Fmod' mRNA 532 516 530 9.33 8.91 9.86 6.54 6.24 5.81 9.366666667 6.196666667 429 400 369 526 399.3333333 0.001250135 -0.410932843 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0030199///collagen fibril organization 14265 14265 'Fmr1' mRNA 567 535 468 7.05 6.56 6.21 6.36 5.06 6.23 6.606666667 5.883333333 589 457 556 523.3333333 534 0.913112082 0.018176541 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005845///mRNA cap binding complex+++GO:0005886///plasma membrane+++GO:0010369///chromocenter+++GO:0010494///cytoplasmic stress granule+++GO:0014069///postsynaptic density+++GO:0015030///Cajal body+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0032797///SMN complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0044297///cell body+++GO:0044326///dendritic spine neck+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0097386///glial cell projection+++GO:0097444///spine apparatus+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol+++GO:1902737///dendritic filopodium+++GO:1904115///axon cytoplasm+++GO:1990124///messenger ribonucleoprotein complex+++GO:1990635///proximal dendrite+++GO:1990812///growth cone filopodium+++GO:1990904///ribonucleoprotein complex" GO:0000340///RNA 7-methylguanosine cap binding+++GO:0002151///G-quadruplex RNA binding+++GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008266///poly(U) RNA binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030371///translation repressor activity+++GO:0031369///translation initiation factor binding+++GO:0033592///RNA strand annealing activity+++GO:0034046///poly(G) binding+++GO:0035064///methylated histone binding+++GO:0035197///siRNA binding+++GO:0035198///miRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043022///ribosome binding+++GO:0044325///ion channel binding+++GO:0045182///translation regulator activity+++GO:0046982///protein heterodimerization activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0070840///dynein complex binding+++GO:1990825///sequence-specific mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002091///negative regulation of receptor internalization+++GO:0002092///positive regulation of receptor internalization+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007215///glutamate receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0008089///anterograde axonal transport+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010955///negative regulation of protein processing+++GO:0017148///negative regulation of translation+++GO:0019226///transmission of nerve impulse+++GO:0031047///gene silencing by RNA+++GO:0033129///positive regulation of histone phosphorylation+++GO:0034644///cellular response to UV+++GO:0035176///social behavior+++GO:0043488///regulation of mRNA stability+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044830///modulation by host of viral RNA genome replication+++GO:0045665///negative regulation of neuron differentiation+++GO:0045727///positive regulation of translation+++GO:0045947///negative regulation of translational initiation+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0050806///positive regulation of synaptic transmission+++GO:0051028///mRNA transport+++GO:0051489///regulation of filopodium assembly+++GO:0051491///positive regulation of filopodium assembly+++GO:0060964///regulation of gene silencing by miRNA+++GO:0060996///dendritic spine development+++GO:0060998///regulation of dendritic spine development+++GO:0060999///positive regulation of dendritic spine development+++GO:0072711///cellular response to hydroxyurea+++GO:0097396///response to interleukin-17+++GO:0098586///cellular response to virus+++GO:0098908///regulation of neuronal action potential+++GO:0098976///excitatory chemical synaptic transmission+++GO:0098977///inhibitory chemical synaptic transmission+++GO:0099577///regulation of translation at presynapse, modulating synaptic transmission+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1900453///negative regulation of long-term synaptic depression+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1901254///positive regulation of intracellular transport of viral material+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1902373///negative regulation of mRNA catabolic process+++GO:1902416///positive regulation of mRNA binding+++GO:1905244///regulation of modification of synaptic structure+++GO:2000301///negative regulation of synaptic vesicle exocytosis+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:2000766///negative regulation of cytoplasmic translation+++GO:2001022///positive regulation of response to DNA damage stimulus" 14266 14266 'Aff2' mRNA 39 37 12 0.37 0.41 0.1 0.19 0.31 0.25 0.293333333 0.25 32 38 38 29.33333333 36 0.624689137 0.303402844 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0032783///ELL-EAF complex GO:0002151///G-quadruplex RNA binding+++GO:0003723///RNA binding GO:0006397///mRNA processing+++GO:0007611///learning or memory+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0035063///nuclear speck organization+++GO:0043484///regulation of RNA splicing 14268 14268 'Fn1' mRNA 215 238 247 1.42 1.55 1.75 57.19 50.77 54.66 1.573333333 54.20666667 9913 8594 9183 233.3333333 9230 0 5.292360774 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++04933///AGE-RAGE signaling pathway in diabetic complications+++05100///Bacterial invasion of epithelial cells+++05135///Yersinia infection+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005577///fibrinogen complex+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016324///apical plasma membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome GO:0002020///protease binding+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008201///heparin binding+++GO:0016504///peptidase activator activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0043394///proteoglycan binding+++GO:0045340///mercury ion binding+++GO:0051087///chaperone binding+++GO:0097718///disordered domain specific binding "GO:0001525///angiogenesis+++GO:0001775///cell activation+++GO:0001932///regulation of protein phosphorylation+++GO:0006953///acute-phase response+++GO:0007044///cell-substrate junction assembly+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008347///glial cell migration+++GO:0008360///regulation of cell shape+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010952///positive regulation of peptidase activity+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0018149///peptide cross-linking+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033622///integrin activation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035987///endodermal cell differentiation+++GO:0042060///wound healing+++GO:0043066///negative regulation of apoptotic process+++GO:0045773///positive regulation of axon extension+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050921///positive regulation of chemotaxis+++GO:0051702///interaction with symbiont+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070527///platelet aggregation+++GO:0071288///cellular response to mercury ion+++GO:0071347///cellular response to interleukin-1+++GO:0071635///negative regulation of transforming growth factor beta production+++GO:0072378///blood coagulation, fibrin clot formation+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1904237///positive regulation of substrate-dependent cell migration, cell attachment to substrate" 142681 142681 'Slc34a3' mRNA 21 15 13 0.58 0.41 0.36 0.07 0.2 0.35 0.45 0.206666667 3 8 14 16.33333333 8.333333333 0.25374781 -0.971443278 "04928///Parathyroid hormone synthesis, secretion and action+++04978///Mineral absorption" GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031982///vesicle GO:0005436///sodium:phosphate symporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0035725///sodium ion transmembrane transport+++GO:0044341///sodium-dependent phosphate transport+++GO:0055085///transmembrane transport 142682 142682 'Zcchc14' mRNA 600 557 477 5.33 4.91 4.38 4.44 4.33 5.51 4.873333333 4.76 590 560 701 544.6666667 617 0.228742912 0.171519214 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0008150///biological_process 142687 142687 'Asb14' mRNA 13 16 13 0.25 0.3 0.27 0.12 0.09 0.09 0.273333333 0.1 7 5 5 14 5.666666667 0.122485812 -1.316767944 GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 142688 142688 'Asb13' mRNA 598 595 618 13.95 13.59 15.2 11.27 10.69 10.87 14.24666667 10.94333333 559 516 520 603.6666667 531.6666667 0.111190689 -0.197043843 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 14269 14269 'Fnbp1' mRNA 2837 2737 2813 34.66 32.41 34.8 30.73 28.1 33.77 33.95666667 30.86666667 2937 2691 3049 2795.666667 2892.333333 0.724050934 0.035602322 05131///Shigellosis GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007399///nervous system development 14270 14270 'Srgap2' mRNA 1727 1791.85 1480 14.25 15.05 12.34 12.8 11.4 11.86 13.88 12.02 1711.9 1506 1500 1666.283333 1572.633333 0.324442947 -0.093142639 04360///Axon guidance GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0045335///phagocytic vesicle GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0003363///lamellipodium assembly involved in ameboidal cell migration+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0021816///extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration+++GO:0030336///negative regulation of cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043547///positive regulation of GTPase activity+++GO:0046847///filopodium assembly+++GO:0048812///neuron projection morphogenesis+++GO:0051014///actin filament severing+++GO:0060996///dendritic spine development+++GO:2001223///negative regulation of neuron migration 14272 14272 'Fnta' mRNA 2275 2449 692 67.61 71.72 21.82 19.34 42.96 37.32 53.71666667 33.20666667 748 1622 1397 1805.333333 1255.666667 0.514990219 -0.503182822 00900///Terpenoid backbone biosynthesis GO:0005737///cytoplasm+++GO:0005875///microtubule associated complex+++GO:0005886///plasma membrane+++GO:0005953///CAAX-protein geranylgeranyltransferase complex+++GO:0005965///protein farnesyltransferase complex GO:0004659///prenyltransferase activity+++GO:0004660///protein farnesyltransferase activity+++GO:0004661///protein geranylgeranyltransferase activity+++GO:0004662///CAAX-protein geranylgeranyltransferase activity+++GO:0004663///Rab geranylgeranyltransferase activity+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0008318///protein prenyltransferase activity+++GO:0016740///transferase activity+++GO:0030548///acetylcholine receptor regulator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0036094///small molecule binding+++GO:0042277///peptide binding+++GO:0043014///alpha-tubulin binding+++GO:1901363///heterocyclic compound binding GO:0007528///neuromuscular junction development+++GO:0008284///positive regulation of cell proliferation+++GO:0010035///response to inorganic substance+++GO:0014070///response to organic cyclic compound+++GO:0018342///protein prenylation+++GO:0018343///protein farnesylation+++GO:0018344///protein geranylgeranylation+++GO:0034097///response to cytokine+++GO:0043066///negative regulation of apoptotic process+++GO:0045213///neurotransmitter receptor metabolic process+++GO:0045787///positive regulation of cell cycle+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0090044///positive regulation of tubulin deacetylation+++GO:0090045///positive regulation of deacetylase activity 14275 14275 'Folr1' mRNA 71 66 72 4.54 4.12 5.12 7.61 5.78 5.7 4.593333333 6.363333333 126 94 89 69.66666667 103 0.062089578 0.547888291 01523///Antifolate resistance+++04144///Endocytosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0046658///anchored component of plasma membrane "GO:0005542///folic acid binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0038023///signaling receptor activity+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0051870///methotrexate binding+++GO:0061714///folic acid receptor activity" GO:0001947///heart looping+++GO:0003147///neural crest cell migration involved in heart formation+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0005975///carbohydrate metabolic process+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0007155///cell adhesion+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0015884///folic acid transport+++GO:0016311///dephosphorylation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0031103///axon regeneration+++GO:0035036///sperm-egg recognition+++GO:0046655///folic acid metabolic process+++GO:0048678///response to axon injury+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0061713///anterior neural tube closure+++GO:0071231///cellular response to folic acid+++GO:1904447///folate import across plasma membrane 14276 14276 'Folr2' mRNA 71 57 77 4.1 3.28 4.71 107.43 108.71 108.46 4.03 108.2 2120 2092 2069 68.33333333 2093.666667 0 4.924764108 01523///Antifolate resistance+++04144///Endocytosis GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane GO:0005542///folic acid binding+++GO:0038023///signaling receptor activity+++GO:0051870///methotrexate binding+++GO:0061714///folic acid receptor activity GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0007155///cell adhesion+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0008284///positive regulation of cell proliferation+++GO:0015884///folic acid transport+++GO:0035036///sperm-egg recognition+++GO:0071231///cellular response to folic acid+++GO:1904447///folate import across plasma membrane 14281 14281 'Fos' mRNA 184 253 166 4.94 6.69 4.73 30.75 33.48 31.5 5.453333333 31.91 1317 1400 1306 201 1341 5.94E-109 2.731829049 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04024///cAMP signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04713///Circadian entrainment+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04932///Non-alcoholic fatty liver disease+++04935///Growth hormone synthesis, secretion and action+++05031///Amphetamine addiction+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05224///Breast cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032993///protein-DNA complex+++GO:0035976///transcription factor AP-1 complex+++GO:0043005///neuron projection "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070412///R-SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001661///conditioned taste aversion+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0009409///response to cold+++GO:0009410///response to xenobiotic stimulus+++GO:0009416///response to light stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009629///response to gravity+++GO:0009636///response to toxic substance+++GO:0010468///regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0030431///sleep+++GO:0031668///cellular response to extracellular stimulus+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0032870///cellular response to hormone stimulus+++GO:0034097///response to cytokine+++GO:0034614///cellular response to reactive oxygen species+++GO:0035902///response to immobilization stress+++GO:0035914///skeletal muscle cell differentiation+++GO:0035994///response to muscle stretch+++GO:0042493///response to drug+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051412///response to corticosterone+++GO:0051591///response to cAMP+++GO:0060395///SMAD protein signal transduction+++GO:0071276///cellular response to cadmium ion+++GO:0071277///cellular response to calcium ion+++GO:1901216///positive regulation of neuron death+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 14282 14282 'Fosb' mRNA 8 12 5 0.11 0.18 0.08 2.45 1.75 1.9 0.123333333 2.033333333 191 133 146 8.333333333 156.6666667 6.64E-27 4.222895459 04380///Osteoclast differentiation+++04657///IL-17 signaling pathway+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007565///female pregnancy+++GO:0009612///response to mechanical stimulus+++GO:0032570///response to progesterone+++GO:0032870///cellular response to hormone stimulus+++GO:0042493///response to drug+++GO:0043278///response to morphine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051412///response to corticosterone+++GO:0051591///response to cAMP+++GO:0071277///cellular response to calcium ion" 14283 14283 'Fosl1' mRNA 0 4.24 1.06 0 0.14 0.04 3.32 3.74 3.27 0.06 3.443333333 112.21 123.36 106.73 1.766666667 114.1 5.97E-17 6.083927515 04310///Wnt signaling pathway+++04380///Osteoclast differentiation+++04657///IL-17 signaling pathway+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007296///vitellogenesis+++GO:0007565///female pregnancy+++GO:0007612///learning+++GO:0008285///negative regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009629///response to gravity+++GO:0014070///response to organic cyclic compound+++GO:0031668///cellular response to extracellular stimulus+++GO:0032570///response to progesterone+++GO:0034097///response to cytokine+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051412///response to corticosterone+++GO:0051591///response to cAMP+++GO:0060674///placenta blood vessel development+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000144///positive regulation of DNA-templated transcription, initiation" 14284 14284 'Fosl2' mRNA 60 64 48 0.54 0.54 0.44 3.12 2.88 3.06 0.506666667 3.02 405 368 401 57.33333333 391.3333333 1.10E-49 2.761836915 04380///Osteoclast differentiation GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001666///response to hypoxia+++GO:0003334///keratinocyte development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation" 14287 14287 'Fpgs' mRNA 379 371 361 9.41 9.05 9.5 8.12 8.86 9.44 9.32 8.806666667 376 401 423 370.3333333 400 0.546239671 0.100336176 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors+++01523///Antifolate resistance GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004326///tetrahydrofolylpolyglutamate synthase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006536///glutamate metabolic process+++GO:0006730///one-carbon metabolic process+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008283///cell proliferation+++GO:0009058///biosynthetic process+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0046901///tetrahydrofolylpolyglutamate biosynthetic process 14289 14289 'Fpr2' mRNA 6 4 11 0.28 0.18 0.55 4.07 3.92 3.95 0.336666667 3.98 100 94 94 7 96 1.01E-16 3.758368943 04080///Neuroactive ligand-receptor interaction+++04613///Neutrophil extracellular trap formation+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding+++GO:0004875///complement receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004982///N-formyl peptide receptor activity+++GO:0005124///scavenger receptor binding+++GO:0038023///signaling receptor activity+++GO:0038024///cargo receptor activity+++GO:0050786///RAGE receptor binding GO:0001774///microglial cell activation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002430///complement receptor mediated signaling pathway+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0019722///calcium-mediated signaling+++GO:0032930///positive regulation of superoxide anion generation+++GO:0042742///defense response to bacterium+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045089///positive regulation of innate immune response+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0048143///astrocyte activation+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050918///positive chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061903///positive regulation of 1-phosphatidylinositol-3-kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:1904646///cellular response to amyloid-beta 14293 14293 'Fpr1' mRNA 45 35 40 2.05 1.57 1.93 8.18 7.12 8.5 1.85 7.933333333 206 175 207 40 196 2.10E-20 2.279500941 04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04613///Neutrophil extracellular trap formation+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001664///G protein-coupled receptor binding+++GO:0004875///complement receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004982///N-formyl peptide receptor activity+++GO:0005124///scavenger receptor binding+++GO:0050786///RAGE receptor binding GO:0002430///complement receptor mediated signaling pathway+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration 14296 14296 'Frat1' mRNA 819 802 919 17.39 16.76 20.7 6.29 5.14 5.62 18.28333333 5.683333333 341 272 295 846.6666667 302.6666667 5.92E-32 -1.501544234 04310///Wnt signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05200///Pathways in cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding GO:0000578///embryonic axis specification+++GO:0006611///protein export from nucleus+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway 14297 14297 'Fxn' mRNA 269.7 261.23 232.79 4.93 4.7 4.51 6.3 6.5 6.11 4.713333333 6.303333333 396.68 399.73 372.74 254.5733333 389.7166667 2.09E-05 0.605204776 00860///Porphyrin metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:1990221///L-cysteine desulfurase complex "GO:0004322///ferroxidase activity+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0034986///iron chaperone activity+++GO:0046872///metal ion binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006119///oxidative phosphorylation+++GO:0006783///heme biosynthetic process+++GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0007628///adult walking behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0009060///aerobic respiration+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010039///response to iron ion+++GO:0010722///regulation of ferrochelatase activity+++GO:0016226///iron-sulfur cluster assembly+++GO:0016540///protein autoprocessing+++GO:0018283///iron incorporation into metallo-sulfur cluster+++GO:0019230///proprioception+++GO:0030307///positive regulation of cell growth+++GO:0040015///negative regulation of multicellular organism growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0045773///positive regulation of axon extension+++GO:0046621///negative regulation of organ growth+++GO:0051349///positive regulation of lyase activity+++GO:0055072///iron ion homeostasis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:1904231///positive regulation of succinate dehydrogenase activity+++GO:1904234///positive regulation of aconitate hydratase activity 142980 142980 'Tlr3' mRNA 810 887 865 9.95 10.57 11.21 12.75 10.6 11.07 10.57666667 11.47333333 1188 971 1009 854 1056 0.005805159 0.291830257 04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++05160///Hepatitis C+++05161///Hepatitis B+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0000165///MAPK cascade+++GO:0001774///microglial cell activation+++GO:0001819///positive regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007252///I-kappaB phosphorylation+++GO:0007254///JNK cascade+++GO:0008584///male gonad development+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0032481///positive regulation of type I interferon production+++GO:0032722///positive regulation of chemokine production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034346///positive regulation of type III interferon production+++GO:0035458///cellular response to interferon-beta+++GO:0035690///cellular response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0043331///response to dsRNA+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0050729///positive regulation of inflammatory response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0071260///cellular response to mechanical stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071360///cellular response to exogenous dsRNA+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097527///necroptotic signaling pathway+++GO:0098586///cellular response to virus+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 14299 14299 'Ncs1' mRNA 329 354 452 4.4 4.65 6.41 2.87 3.34 3.63 5.153333333 3.28 247 281 303 378.3333333 277 0.011398879 -0.467589041 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0000287///magnesium ion binding+++GO:0005245///voltage-gated calcium channel activity+++GO:0005509///calcium ion binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels GO:0010975///regulation of neuron projection development+++GO:0045921///positive regulation of exocytosis+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050806///positive regulation of synaptic transmission+++GO:0070588///calcium ion transmembrane transport+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 14300 14300 'Frg1' mRNA 829.51 820.19 774.64 42.61 40.47 41.31 43.55 49.36 44.63 41.46333333 45.84666667 924.36 1035.5 914.43 808.1133333 958.0966667 0.024578684 0.235642336 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0030018///Z disc+++GO:0055120///striated muscle dense body+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0007517///muscle organ development+++GO:0008380///RNA splicing+++GO:0042254///ribosome biogenesis 14302 14302 'Frk' mRNA 344 384 370 3.87 4.27 4.46 4.34 4.13 4.29 4.2 4.253333333 442 408 424 366 424.6666667 0.166108913 0.201582093 04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0045087///innate immune response 14311 14311 'Cidec' mRNA 1 0 2 0.03 0 0.07 0 0 0.03 0.033333333 0.01 0 0 1 1 0.333333333 0.716186228 -1.529828329 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0034389///lipid droplet organization+++GO:0042981///regulation of apoptotic process+++GO:0097194///execution phase of apoptosis 14312 14312 'Brd2' mRNA 1826.72 1946.84 1467.85 26.88 28.82 23.34 34.8 28.9 34.2 26.34666667 32.63333333 2557.2 2150.76 2461.96 1747.136667 2389.973333 4.91E-07 0.444375031 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003682///chromatin binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0031493///nucleosomal histone binding+++GO:0070577///lysine-acetylated histone binding "GO:0001843///neural tube closure+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0010468///regulation of gene expression" 14313 14313 'Fst' mRNA 18 29 7 0.38 0.58 0.14 0.77 1.12 1.69 0.366666667 1.193333333 41 60 87 18 62.66666667 2.81E-04 1.810379545 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0038102///activin receptor antagonist activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048185///activin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007389///pattern specification process+++GO:0008585///female gonad development+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0030510///regulation of BMP signaling pathway+++GO:0031069///hair follicle morphogenesis+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043616///keratinocyte proliferation+++GO:0045596///negative regulation of cell differentiation+++GO:0051798///positive regulation of hair follicle development 14314 14314 'Fstl1' mRNA 1557 1692 1641 23.42 25.04 26.18 35.16 32.09 33.36 24.88 33.53666667 2690 2398 2472 1630 2520 1.58E-16 0.615080918 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030510///regulation of BMP signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045446///endothelial cell differentiation+++GO:0061484///hematopoietic stem cell homeostasis 14319 14319 'Fth1' mRNA 56478 55778 54370 3892.13 3803.46 3975.82 9702.34 9839.56 9660.48 3890.47 9734.126667 161350 159454 155219 55542 158674.3333 2.88E-234 1.502361487 04216///Ferroptosis+++04217///Necroptosis+++04978///Mineral absorption GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0044754///autolysosome+++GO:0071682///endocytic vesicle lumen GO:0004322///ferroxidase activity+++GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006880///intracellular sequestering of iron ion+++GO:0006955///immune response+++GO:0008285///negative regulation of cell proliferation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0060547///negative regulation of necrotic cell death 14325 14325 'Ftl1' mRNA 43235.64 44126.68 42699.04 2871.57 2899.14 3009.18 7420.73 7842.07 7435.45 2926.63 7566.083333 128072.08 131902.85 123998.47 43353.78667 127991.1333 2.14E-207 1.550033014 04216///Ferroptosis+++04217///Necroptosis+++04978///Mineral absorption GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0008043///intracellular ferritin complex+++GO:0044754///autolysosome+++GO:0071682///endocytic vesicle lumen GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006880///intracellular sequestering of iron ion 14339 14339 'Aktip' mRNA 2960.58 3044.88 2808.88 75.55 76.93 76.57 42.15 42.28 43.2 76.35 42.54333333 1893.73 1836.43 1878.56 2938.113333 1869.573333 4.03E-26 -0.663289365 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030897///HOPS complex+++GO:0070695///FHF complex GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0032092///positive regulation of protein binding+++GO:0045022///early endosome to late endosome transport+++GO:1905719///protein localization to perinuclear region of cytoplasm 14343 14343 'Fut1' mRNA 74 64 53 1.63 1.36 1.27 1.33 1.48 0.83 1.42 1.213333333 71 74 42 63.66666667 62.33333333 0.932123331 -0.038477749 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008107///galactoside 2-alpha-L-fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0031127///alpha-(1,2)-fucosyltransferase activity" GO:0001936///regulation of endothelial cell proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0021772///olfactory bulb development+++GO:0030155///regulation of cell adhesion+++GO:0036065///fucosylation+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin 14344 14344 'Fut2' mRNA 170.98 208.96 135.79 3.14 3.77 2.66 3.02 2.23 2.46 3.19 2.57 187.65 136 151 171.91 158.2166667 0.665933987 -0.121576558 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008107///galactoside 2-alpha-L-fucosyltransferase activity+++GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0031127///alpha-(1,2)-fucosyltransferase activity" GO:0001936///regulation of endothelial cell proliferation+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006664///glycolipid metabolic process+++GO:0030155///regulation of cell adhesion+++GO:0036065///fucosylation 14345 14345 'Fut4' mRNA 74 53 64 1.1 0.77 1 1.39 1.26 1.18 0.956666667 1.276666667 108 96 89 63.66666667 97.66666667 0.044017312 0.602963616 00515///Mannose type O-glycan biosynthesis+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0071944///cell periphery "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0017083///4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0009311///oligosaccharide metabolic process+++GO:0036065///fucosylation+++GO:1903037///regulation of leukocyte cell-cell adhesion+++GO:1903238///positive regulation of leukocyte tethering or rolling 14347 14347 'Fut7' mRNA 2 1 1 0.07 0.03 0.03 0.32 0.2 0.41 0.043333333 0.31 12 7 14 1.333333333 11 0.012821993 3.032856975 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0017083///4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" "GO:0001807///regulation of type IV hypersensitivity+++GO:0002361///CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0002522///leukocyte migration involved in immune response+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006486///protein glycosylation+++GO:0006672///ceramide metabolic process+++GO:0006954///inflammatory response+++GO:0007566///embryo implantation+++GO:0022407///regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0036065///fucosylation+++GO:0045785///positive regulation of cell adhesion+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0060353///regulation of cell adhesion molecule production+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:1903037///regulation of leukocyte cell-cell adhesion+++GO:1903236///regulation of leukocyte tethering or rolling+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1904994///regulation of leukocyte adhesion to vascular endothelial cell+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:2000389///regulation of neutrophil extravasation" 14348 14348 'Fut9' mRNA 580 609 545 2.52 2.6 2.52 2.09 1.96 2.25 2.546666667 2.1 553 507 577 578 545.6666667 0.493523012 -0.093859237 00515///Mannose type O-glycan biosynthesis+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0032588///trans-Golgi network membrane "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0017083///4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0007399///nervous system development+++GO:0010976///positive regulation of neuron projection development+++GO:0030182///neuron differentiation+++GO:0033692///cellular polysaccharide biosynthetic process+++GO:0036065///fucosylation+++GO:1903037///regulation of leukocyte cell-cell adhesion+++GO:1903236///regulation of leukocyte tethering or rolling 14349 14349 'Fv1' mRNA 126 139 110 5.47 5.95 5.06 3.7 2.6 3.48 5.493333333 3.26 98 67 89 125 84.66666667 0.02982919 -0.57276701 GO:0005794///Golgi apparatus GO:0009615///response to virus+++GO:0016032///viral process+++GO:0051607///defense response to virus 14356 14356 'Timm10b' mRNA 749 689 666 53.8 49.48 51.07 70.74 74.97 69.78 51.45 71.83 1083 1117 1062 701.3333333 1087.333333 2.69E-11 0.621942965 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0042719///mitochondrial intermembrane space protein transporter complex+++GO:0042721///TIM22 mitochondrial import inner membrane insertion complex GO:0046872///metal ion binding GO:0015031///protein transport 14357 14357 'Dtx1' mRNA 162 195 61 2.36 2.75 0.94 0.79 0.81 0.76 2.016666667 0.786666667 62 63 58 139.3333333 61 7.36E-04 -1.182590664 04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0008593///regulation of Notch signaling pathway+++GO:0010001///glial cell differentiation+++GO:0016567///protein ubiquitination+++GO:0045581///negative regulation of T cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:1990830///cellular response to leukemia inhibitory factor 14359 14359 'Fxr1' mRNA 904 940 847 23.08 23.33 22.51 23.92 23.1 23 22.97333333 23.34 1083 1007 1010 897 1033.333333 0.03835984 0.193082469 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0035770///ribonucleoprotein granule+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043025///neuronal cell body+++GO:0043034///costamere+++GO:0043197///dendritic spine+++GO:0044326///dendritic spine neck+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:1902737///dendritic filopodium GO:0002151///G-quadruplex RNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0033592///RNA strand annealing activity+++GO:0042803///protein homodimerization activity+++GO:0045182///translation regulator activity+++GO:0046982///protein heterodimerization activity "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation+++GO:0051489///regulation of filopodium assembly+++GO:0060538///skeletal muscle organ development+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:2001022///positive regulation of response to DNA damage stimulus" 14360 14360 'Fyn' mRNA 429 426 410 5.63 5.98 6.13 5.15 5.25 5.09 5.913333333 5.163333333 426 416 406 421.6666667 416 0.863090843 -0.031171151 04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04360///Axon guidance+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04520///Adherens junction+++04611///Platelet activation+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04725///Cholinergic synapse+++05020///Prion disease+++05130///Pathogenic Escherichia coli infection+++05416///Viral myocarditis "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0097386///glial cell projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0042608///T cell receptor binding+++GO:0042609///CD4 receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0043274///phospholipase binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046875///ephrin receptor binding+++GO:0048156///tau protein binding+++GO:0051428///peptide hormone receptor binding+++GO:0070851///growth factor receptor binding+++GO:0097110///scaffold protein binding+++GO:0097718///disordered domain specific binding GO:0000304///response to singlet oxygen+++GO:0001764///neuron migration+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0003015///heart process+++GO:0006468///protein phosphorylation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008360///regulation of cell shape+++GO:0010629///negative regulation of gene expression+++GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042177///negative regulation of protein catabolic process+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042542///response to hydrogen peroxide+++GO:0042552///myelination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0045471///response to ethanol+++GO:0046777///protein autophosphorylation+++GO:0048813///dendrite morphogenesis+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050798///activated T cell proliferation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050852///T cell receptor signaling pathway+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0071363///cellular response to growth factor stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1900449///regulation of glutamate receptor signaling pathway+++GO:1901216///positive regulation of neuron death+++GO:1902951///negative regulation of dendritic spine maintenance+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:1904645///response to amyloid-beta+++GO:1904646///cellular response to amyloid-beta+++GO:1905232///cellular response to L-glutamate+++GO:1905430///cellular response to glycine+++GO:1905664///regulation of calcium ion import across plasma membrane+++GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 14362 14362 'Fzd1' mRNA 241 257 75 2.96 3.1 0.98 3.18 3.36 3.35 2.346666667 3.296666667 298 308 304 191 303.3333333 0.235605956 0.679654628 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0017147///Wnt-protein binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042813///Wnt-activated receptor activity+++GO:0046982///protein heterodimerization activity "GO:0001934///positive regulation of protein phosphorylation+++GO:0003149///membranous septum morphogenesis+++GO:0003150///muscular septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009410///response to xenobiotic stimulus+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0035425///autocrine signaling+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0036520///astrocyte-dopaminergic neuron signaling+++GO:0042493///response to drug+++GO:0044338///canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation+++GO:0044339///canonical Wnt signaling pathway involved in osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060022///hard palate development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060412///ventricular septum morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1905606///regulation of presynapse assembly" 14365 14365 'Fzd3' mRNA 1334 1370 1118 5.46 5.51 4.85 3.68 3.68 3.89 5.273333333 3.75 1037 1014 1060 1274 1037 6.18E-04 -0.305167062 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032433///filopodium tip+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell+++GO:0048786///presynaptic active zone GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity "GO:0001736///establishment of planar polarity+++GO:0001764///neuron migration+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0016055///Wnt signaling pathway+++GO:0030901///midbrain development+++GO:0033278///cell proliferation in midbrain+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0036514///dopaminergic neuron axon guidance+++GO:0036515///serotonergic neuron axon guidance+++GO:0042472///inner ear morphogenesis+++GO:0042493///response to drug+++GO:0045976///negative regulation of mitotic cell cycle, embryonic+++GO:0051602///response to electrical stimulus+++GO:0060070///canonical Wnt signaling pathway+++GO:0061549///sympathetic ganglion development+++GO:0071679///commissural neuron axon guidance+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:1904938///planar cell polarity pathway involved in axon guidance" 14366 14366 'Fzd4' mRNA 770 794.62 707.28 7.67 7.52 7.29 3.36 3.05 3.46 7.493333333 3.29 394 352.27 382 757.3 376.09 3.60E-21 -1.020406971 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0001540///amyloid-beta binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0019955///cytokine binding+++GO:0030165///PDZ domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0038023///signaling receptor activity+++GO:0042803///protein homodimerization activity+++GO:0042813///Wnt-activated receptor activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity "GO:0001553///luteinization+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0016055///Wnt signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031987///locomotion involved in locomotory behavior+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035426///extracellular matrix-cell signaling+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0042701///progesterone secretion+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060070///canonical Wnt signaling pathway+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0061301///cerebellum vasculature morphogenesis+++GO:0061304///retinal blood vessel morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0150012///positive regulation of neuron projection arborization+++GO:1990830///cellular response to leukemia inhibitory factor" 14367 14367 'Fzd5' mRNA 34 29 25 0.26 0.22 0.21 0.61 0.35 0.4 0.23 0.453333333 91 52 58 29.33333333 67 0.002577473 1.177919119 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0001540///amyloid-beta binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0017147///Wnt-protein binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042813///Wnt-activated receptor activity+++GO:0044877///protein-containing complex binding "GO:0000578///embryonic axis specification+++GO:0001525///angiogenesis+++GO:0001944///vasculature development+++GO:0002726///positive regulation of T cell cytokine production+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0031076///embryonic camera-type eye development+++GO:0031077///post-embryonic camera-type eye development+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033077///T cell differentiation in thymus+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0060061///Spemann organizer formation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0060716///labyrinthine layer blood vessel development+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0099054///presynapse assembly+++GO:1901382///regulation of chorionic trophoblast cell proliferation+++GO:2000810///regulation of bicellular tight junction assembly" 14368 14368 'Fzd6' mRNA 1391 1534 1352 18.54 20.17 19.1 10.77 10.51 11.99 19.27 11.09 935 884 1003 1425.666667 940.6666667 1.93E-12 -0.610444326 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045177///apical part of cell GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042813///Wnt-activated receptor activity "GO:0001736///establishment of planar polarity+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0016055///Wnt signaling pathway+++GO:0030168///platelet activation+++GO:0030901///midbrain development+++GO:0033278///cell proliferation in midbrain+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0035880///embryonic nail plate morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0048105///establishment of body hair planar orientation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 14369 14369 'Fzd7' mRNA 854 926 525 9.5 10.13 6.2 4.9 4.67 5.35 8.61 4.973333333 507 472 536 768.3333333 505 1.06E-04 -0.606194422 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane "GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0017147///Wnt-protein binding+++GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0016055///Wnt signaling pathway+++GO:0019827///stem cell population maintenance+++GO:0033077///T cell differentiation in thymus+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0042666///negative regulation of ectodermal cell fate specification+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048103///somatic stem cell division+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0060070///canonical Wnt signaling pathway+++GO:0060231///mesenchymal to epithelial transition+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:2000726///negative regulation of cardiac muscle cell differentiation" 14370 14370 'Fzd8' mRNA 44 29 41 0.72 0.47 0.71 0.42 0.41 0.57 0.633333333 0.466666667 30 28 39 38 32.33333333 0.652036678 -0.248696016 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990851///Wnt-Frizzled-LRP5/6 complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0030165///PDZ domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042813///Wnt-activated receptor activity GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0033077///T cell differentiation in thymus+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043507///positive regulation of JUN kinase activity+++GO:0060070///canonical Wnt signaling pathway 14371 14371 'Fzd9' mRNA 2104 2313 656 56.45 61.13 18.67 19.27 22.92 32.33 45.41666667 24.84 826 959 1341 1691 1042 0.291438787 -0.68312948 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031527///filopodium membrane+++GO:0031966///mitochondrial membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0042803///protein homodimerization activity+++GO:0042813///Wnt-activated receptor activity+++GO:0046982///protein heterodimerization activity GO:0001503///ossification+++GO:0001836///release of cytochrome c from mitochondria+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007405///neuroblast proliferation+++GO:0007611///learning or memory+++GO:0016055///Wnt signaling pathway+++GO:0030183///B cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051726///regulation of cell cycle+++GO:0051902///negative regulation of mitochondrial depolarization+++GO:0060070///canonical Wnt signaling pathway+++GO:0060546///negative regulation of necroptotic process+++GO:0071157///negative regulation of cell cycle arrest+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099173///postsynapse organization+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1904393///regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:1904394///negative regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:1990523///bone regeneration+++GO:2000179///positive regulation of neural precursor cell proliferation 14373 14373 'G0s2' mRNA 2135 2175 2162 169.69 171.25 182.35 126.39 134.76 124.63 174.43 128.5933333 1821 1891 1734 2157.333333 1815.333333 8.64E-04 -0.261306461 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006915///apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 14375 14375 'Xrcc6' mRNA 609.05 638.09 586.99 15.9 16.44 16.54 14.15 13.75 12.89 16.29333333 13.59666667 608.8 581 528 611.3766667 572.6 0.423714631 -0.105761075 03450///Non-homologous end-joining GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0043564///Ku70:Ku80 complex+++GO:0070419///nonhomologous end joining complex GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003824///catalytic activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0030332///cyclin binding+++GO:0042162///telomeric DNA binding+++GO:0044877///protein-containing complex binding+++GO:0045027///DNA end binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0097110///scaffold protein binding "GO:0000723///telomere maintenance+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007420///brain development+++GO:0008152///metabolic process+++GO:0010212///response to ionizing radiation+++GO:0032508///DNA duplex unwinding+++GO:0033151///V(D)J recombination+++GO:0045087///innate immune response+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0071475///cellular hyperosmotic salinity response+++GO:0071480///cellular response to gamma radiation+++GO:0071481///cellular response to X-ray+++GO:0097680///double-strand break repair via classical nonhomologous end joining" 14376 14376 'Ganab' mRNA 3472 3611 3363 47.83 48.97 49.15 50.68 47 47.47 48.65 48.38333333 4235 3833 3839 3482 3969 0.005430374 0.176720824 00510///N-Glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0017177///glucosidase II complex+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0005515///protein binding+++GO:0015926///glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0033919///glucan 1,3-alpha-glucosidase activity+++GO:0090599///alpha-glucosidase activity" GO:0005975///carbohydrate metabolic process+++GO:0006491///N-glycan processing+++GO:0008152///metabolic process 14381 14381 'G6pdx' mRNA 4500 4827 4734 107.88 113.94 120.39 99.86 99.12 96.23 114.07 98.40333333 4791 4643 4469 4687 4634.333333 0.743370509 -0.029419185 00030///Pentose phosphate pathway+++00480///Glutathione metabolism+++01200///Carbon metabolism+++05230///Central carbon metabolism in cancer+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle "GO:0004345///glucose-6-phosphate dehydrogenase activity+++GO:0005536///glucose binding+++GO:0016491///oxidoreductase activity+++GO:0016614///oxidoreductase activity, acting on CH-OH group of donors+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0050661///NADP binding" "GO:0001816///cytokine production+++GO:0001998///angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure+++GO:0002033///angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0006695///cholesterol biosynthetic process+++GO:0006739///NADP metabolic process+++GO:0006740///NADPH regeneration+++GO:0006741///NADP biosynthetic process+++GO:0006749///glutathione metabolic process+++GO:0006979///response to oxidative stress+++GO:0009051///pentose-phosphate shunt, oxidative branch+++GO:0010734///negative regulation of protein glutathionylation+++GO:0019322///pentose biosynthetic process+++GO:0032613///interleukin-10 production+++GO:0032615///interleukin-12 production+++GO:0034599///cellular response to oxidative stress+++GO:0040014///regulation of multicellular organism growth+++GO:0043249///erythrocyte maturation+++GO:0043523///regulation of neuron apoptotic process+++GO:0045471///response to ethanol+++GO:0046390///ribose phosphate biosynthetic process+++GO:0048821///erythrocyte development+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:1904879///positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 14385 14385 'Slc37a4' mRNA 659 719 571 17.59 18.71 15.91 12.17 12.5 11.86 17.40333333 12.17666667 540 530 507 649.6666667 525.6666667 0.00695663 -0.313874047 04973///Carbohydrate digestion and absorption GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015152///glucose-6-phosphate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity GO:0001780///neutrophil homeostasis+++GO:0001816///cytokine production+++GO:0002318///myeloid progenitor cell differentiation+++GO:0005977///glycogen metabolic process+++GO:0006089///lactate metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0007584///response to nutrient+++GO:0008202///steroid metabolic process+++GO:0009749///response to glucose+++GO:0014070///response to organic cyclic compound+++GO:0015760///glucose-6-phosphate transport+++GO:0030593///neutrophil chemotaxis+++GO:0032682///negative regulation of chemokine production+++GO:0035166///post-embryonic hemopoiesis+++GO:0035435///phosphate ion transmembrane transport+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0043085///positive regulation of catalytic activity+++GO:0045730///respiratory burst+++GO:0055085///transmembrane transport 14387 14387 'Gaa' mRNA 6779 7077 7184 104 107.02 117.42 85.09 86.13 85.57 109.48 85.59666667 6364 6298 6212 7013.333333 6291.333333 0.010421544 -0.170269172 00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004558///alpha-1,4-glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0032450///maltose alpha-glucosidase activity+++GO:0090599///alpha-glucosidase activity" GO:0000023///maltose metabolic process+++GO:0002026///regulation of the force of heart contraction+++GO:0002086///diaphragm contraction+++GO:0003007///heart morphogenesis+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process+++GO:0006941///striated muscle contraction+++GO:0007040///lysosome organization+++GO:0007626///locomotory behavior+++GO:0008152///metabolic process+++GO:0009888///tissue development+++GO:0043181///vacuolar sequestering+++GO:0046716///muscle cell cellular homeostasis+++GO:0050884///neuromuscular process controlling posture+++GO:0050885///neuromuscular process controlling balance+++GO:0060048///cardiac muscle contraction 14388 14388 'Gab1' mRNA 2874.79 3017.8 2770.31 22.95 25 23.97 18.56 17.43 17.38 23.97333333 17.79 2952.67 2679.51 2689.34 2887.633333 2773.84 0.358194054 -0.069768904 01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04722///Neurotrophin signaling pathway+++05100///Bacterial invasion of epithelial cells+++05205///Proteoglycans in cancer+++05211///Renal cell carcinoma+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005911///cell-cell junction GO:0005515///protein binding GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0007507///heart development+++GO:0008544///epidermis development+++GO:0030334///regulation of cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0035728///response to hepatocyte growth factor+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045766///positive regulation of angiogenesis+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0060711///labyrinthine layer development+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0090668///endothelial cell chemotaxis to vascular endothelial growth factor 14389 14389 'Gab2' mRNA 384 406 380 3.39 3.53 3.56 4.56 4.11 4.32 3.493333333 4.33 595 523 545 390 554.3333333 4.14E-05 0.494927828 04014///Ras signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04380///Osteoclast differentiation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05220///Chronic myeloid leukemia GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex "GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016477///cell migration+++GO:0030316///osteoclast differentiation+++GO:0035556///intracellular signal transduction+++GO:0043306///positive regulation of mast cell degranulation+++GO:0048015///phosphatidylinositol-mediated signaling 14390 14390 'Gabpa' mRNA 820.04 934 844.12 9.03 10.05 9.75 10.28 9.74 11.11 9.61 10.37666667 1068.16 992.17 1123.13 866.0533333 1061.153333 0.004576977 0.281467778 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0033613///activating transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001825///blastocyst formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903351///cellular response to dopamine" 14391 14391 'Gabpb1' mRNA 813.94 754.59 807.84 9.83 9.33 12.14 12.33 11.18 10.21 10.43333333 11.24 889.91 790.67 813.68 792.1233333 831.42 0.681629088 0.055703812 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding GO:0007005///mitochondrion organization+++GO:0045944///positive regulation of transcription by RNA polymerase II 14394 14394 'Gabra1' mRNA 1 6 3 0.01 0.07 0.04 0.01 0.02 0.02 0.04 0.016666667 1 2 2 3.333333333 1.666666667 0.612205941 -1.000414315 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902710///GABA receptor complex+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0008503///benzodiazepine receptor activity+++GO:0016917///GABA receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0050809///diazepam binding+++GO:0097159///organic cyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071420///cellular response to histamine+++GO:1902476///chloride transmembrane transport+++GO:1904862///inhibitory synapse assembly" 14395 14395 'Gabra2' mRNA 7.25 15.2 7.02 0.08 0.17 0.1 0.1 0.09 0.09 0.116666667 0.093333333 9.08 8.23 8.32 9.823333333 8.543333333 0.859232487 -0.21662663 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001505///regulation of neurotransmitter levels+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0006836///neurotransmitter transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport+++GO:1904862///inhibitory synapse assembly" 14396 14396 'Gabra3' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport" 14397 14397 'Gabra4' mRNA 27 31 24 0.35 0.4 0.34 0.17 0.27 0.15 0.363333333 0.196666667 15 23 12 27.33333333 16.66666667 0.230811105 -0.719024737 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007417///central nervous system development+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport" 14399 14399 'Gabra6' mRNA 7.56 6 12 0.17 0.15 0.29 0.15 0 0.21 0.203333333 0.12 8.23 0 10.24 8.52 6.156666667 0.720541501 -0.510068433 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++04742///Taste transduction+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0034707///chloride channel complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099192///cerebellar Golgi cell to granule cell synapse+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0044877///protein-containing complex binding+++GO:0050809///diazepam binding+++GO:1901363///heterocyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport" 14400 14400 'Gabrb1' mRNA 102 121 119 0.37 0.43 0.46 0.09 0.05 0.08 0.42 0.073333333 30 16 25 114 23.66666667 4.39E-12 -2.284768963 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098982///GABA-ergic synapse+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005253///anion channel activity+++GO:0005254///chloride channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0050811///GABA receptor binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0009636///response to toxic substance+++GO:0021954///central nervous system neuron development+++GO:0032570///response to progesterone+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042698///ovulation cycle+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071420///cellular response to histamine+++GO:1902476///chloride transmembrane transport 14401 14401 'Gabrb2' mRNA 3 3 2 0.02 0.02 0.02 0.01 0.02 0 0.02 0.01 1 3 0 2.666666667 1.333333333 0.664494493 -0.996694161 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902710///GABA receptor complex+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0016917///GABA receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007605///sensory perception of sound+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048666///neuron development+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060119///inner ear receptor cell development+++GO:0060384///innervation+++GO:0071420///cellular response to histamine+++GO:0090102///cochlea development+++GO:1901215///negative regulation of neuron death+++GO:1902476///chloride transmembrane transport+++GO:1904862///inhibitory synapse assembly" 14402 14402 'Gabrb3' mRNA 423 434 370 4.04 4.08 3.77 0.18 0.31 0.24 3.963333333 0.243333333 21 36 28 409 28.33333333 1.82E-66 -3.859011273 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0035612///AP-2 adaptor complex binding+++GO:0042802///identical protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007605///sensory perception of sound+++GO:0007612///learning+++GO:0007613///memory+++GO:0009410///response to xenobiotic stimulus+++GO:0019098///reproductive behavior+++GO:0021549///cerebellum development+++GO:0034220///ion transmembrane transport+++GO:0035176///social behavior+++GO:0035640///exploration behavior+++GO:0042391///regulation of membrane potential+++GO:0042493///response to drug+++GO:0042747///circadian sleep/wake cycle, REM sleep+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048666///neuron development+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060021///roof of mouth development+++GO:0060022///hard palate development+++GO:0060080///inhibitory postsynaptic potential+++GO:0060119///inner ear receptor cell development+++GO:0060384///innervation+++GO:0061744///motor behavior+++GO:0071294///cellular response to zinc ion+++GO:0071420///cellular response to histamine+++GO:0072347///response to anesthetic+++GO:0090102///cochlea development+++GO:1901215///negative regulation of neuron death+++GO:1902476///chloride transmembrane transport+++GO:1904862///inhibitory synapse assembly" 14403 14403 'Gabrd' mRNA 11 14 16 0.34 0.42 0.49 0.19 0.08 0 0.416666667 0.09 7 3 0 13.66666667 3.333333333 0.045746365 -2.062895501 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport 14404 14404 'Gabre' mRNA 135 147 84 3.55 3.65 2.4 1.32 1.83 1.83 3.2 1.66 62 80 78 122 73.33333333 0.011336612 -0.7338309 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport+++GO:2001226///negative regulation of chloride transport" 14405 14405 'Gabrg1' mRNA 0 2.16 1 0 0.02 0.04 0 0.06 0 0.02 0.02 0 5 0 1.053333333 1.666666667 0.828636485 0.752549783 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0050811///GABA receptor binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport" 14406 14406 'Gabrg2' mRNA 4 7 7 0.05 0.09 0.11 0 0 0.03 0.083333333 0.01 0 0 2 6 0.666666667 0.074035327 -3.183779424 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:1902710///GABA receptor complex+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0008503///benzodiazepine receptor activity+++GO:0016917///GABA receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0009791///post-embryonic development+++GO:0030534///adult behavior+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071420///cellular response to histamine+++GO:1902476///chloride transmembrane transport+++GO:1904862///inhibitory synapse assembly" 14407 14407 'Gabrg3' mRNA 2 7 1 0.01 0.04 0.01 0 0 0 0.02 0 0 1 0 3.333333333 0.333333333 0.176197894 -3.201082039 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032590///dendrite membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099699///integral component of synaptic membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008503///benzodiazepine receptor activity+++GO:0022851///GABA-gated chloride ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0009410///response to xenobiotic stimulus+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042493///response to drug+++GO:0050877///nervous system process+++GO:0051932///synaptic transmission, GABAergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport" 14408 14408 'Gabrr1' mRNA 7 12 15 0.17 0.3 0.4 0.05 0.17 0 0.29 0.073333333 2 7 0 11.33333333 3 0.095538881 -1.931887168 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0016917///GABA receptor activity+++GO:0019904///protein domain specific binding+++GO:0030594///neurotransmitter receptor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0099505///regulation of presynaptic membrane potential+++GO:1902476///chloride transmembrane transport 14409 14409 'Gabrr2' mRNA 10 9 13 0.4 0.36 0.51 0.17 0.21 0.07 0.423333333 0.15 5 6 2 10.66666667 4.333333333 0.196005066 -1.319181668 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098982///GABA-ergic synapse+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0019904///protein domain specific binding+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007601///visual perception+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042462///eye photoreceptor cell development+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1902476///chloride transmembrane transport 14411 14411 'Slc6a12' mRNA 7 13 10 0.17 0.31 0.24 2.07 2.34 2.03 0.24 2.146666667 98 108 92 10 99.33333333 3.53E-16 3.302460734 04721///Synaptic vesicle cycle+++04727///GABAergic synapse GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0005332///gamma-aminobutyric acid:sodium symporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0006836///neurotransmitter transport+++GO:0009992///cellular water homeostasis+++GO:0015718///monocarboxylic acid transport+++GO:0015812///gamma-aminobutyric acid transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport 14412 14412 'Slc6a13' mRNA 230 253 239 7.66 8.12 8.32 5.88 7.73 6.96 8.033333333 6.856666667 204 256 250 240.6666667 236.6666667 0.879232864 -0.034037587 04721///Synaptic vesicle cycle+++04727///GABAergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection GO:0005308///creatine transmembrane transporter activity+++GO:0005332///gamma-aminobutyric acid:sodium symporter activity+++GO:0005368///taurine transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015185///gamma-aminobutyric acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0042165///neurotransmitter binding GO:0006836///neurotransmitter transport+++GO:0010940///positive regulation of necrotic cell death+++GO:0015718///monocarboxylic acid transport+++GO:0015734///taurine transport+++GO:0015812///gamma-aminobutyric acid transport+++GO:0015881///creatine transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051939///gamma-aminobutyric acid import+++GO:0055085///transmembrane transport+++GO:0071705///nitrogen compound transport+++GO:0089718///amino acid import across plasma membrane 14415 14415 'Gad1' mRNA 2672 2733 2708 45.32 45.51 48.76 10.11 9.31 9.4 46.53 9.606666667 684 623 616 2704.333333 641 2.24E-156 -2.090226308 "00250///Alanine, aspartate and glutamate metabolism+++00410///beta-Alanine metabolism+++00430///Taurine and hypotaurine metabolism+++00650///Butanoate metabolism+++04727///GABAergic synapse+++04940///Type I diabetes mellitus" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005938///cell cortex+++GO:0030424///axon+++GO:0043679///axon terminus+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060077///inhibitory synapse+++GO:0061202///clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane GO:0003824///catalytic activity+++GO:0004351///glutamate decarboxylase activity+++GO:0016595///glutamate binding+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0009449///gamma-aminobutyric acid biosynthetic process+++GO:0019752///carboxylic acid metabolic process+++GO:0035176///social behavior+++GO:0035641///locomotory exploration behavior+++GO:0042136///neurotransmitter biosynthetic process+++GO:0042493///response to drug 14417 14417 'Gad2' mRNA 13.07 23.94 26.37 0.12 0.23 0.26 0.04 0.04 0.07 0.203333333 0.05 4.41 5.26 8.08 21.12666667 5.916666667 0.013285943 -1.884561287 "00250///Alanine, aspartate and glutamate metabolism+++00410///beta-Alanine metabolism+++00430///Taurine and hypotaurine metabolism+++00650///Butanoate metabolism+++04727///GABAergic synapse+++04940///Type I diabetes mellitus" GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031225///anchored component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060077///inhibitory synapse+++GO:0061202///clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane GO:0003824///catalytic activity+++GO:0004351///glutamate decarboxylase activity+++GO:0016595///glutamate binding+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0044877///protein-containing complex binding GO:0006540///glutamate decarboxylation to succinate+++GO:0019752///carboxylic acid metabolic process+++GO:0042136///neurotransmitter biosynthetic process+++GO:0042493///response to drug 14419 14419 'Gal' mRNA 13 15 7 1.13 1.29 0.65 1.52 3.43 3.07 1.023333333 2.673333333 20 44 39 11.66666667 34.33333333 0.008079916 1.562570799 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0043025///neuronal cell body GO:0004966///galanin receptor activity+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0031763///galanin receptor binding+++GO:0031764///type 1 galanin receptor binding+++GO:0031765///type 2 galanin receptor binding+++GO:0031766///type 3 galanin receptor binding GO:0006954///inflammatory response+++GO:0007218///neuropeptide signaling pathway+++GO:0007399///nervous system development+++GO:0007631///feeding behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0010737///protein kinase A signaling+++GO:0019933///cAMP-mediated signaling+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:0051464///positive regulation of cortisol secretion+++GO:0051795///positive regulation of timing of catagen+++GO:1902608///positive regulation of large conductance calcium-activated potassium channel activity 14420 14420 'Galc' mRNA 636.54 656.73 509.77 9.63 9.59 8.12 8.82 8.07 8.78 9.113333333 8.556666667 690.04 615.83 664.73 601.0133333 656.8666667 0.362868336 0.120521462 00600///Sphingolipid metabolism+++04142///Lysosome GO:0005739///mitochondrion+++GO:0005764///lysosome "GO:0003824///catalytic activity+++GO:0004336///galactosylceramidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006683///galactosylceramide catabolic process+++GO:0008152///metabolic process+++GO:0016042///lipid catabolic process+++GO:0042552///myelination 14421 14421 'B4galnt1' mRNA 1036.03 1091.82 811.99 26.43 27.02 21.47 29.51 33.03 30.75 24.97333333 31.09666667 1376.86 1531.1 1395.88 979.9466667 1434.613333 5.91E-08 0.54484732 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0003947///(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0007283///spermatogenesis+++GO:0019915///lipid storage+++GO:0030259///lipid glycosylation 14422 14422 'B4galnt2' mRNA 23.58 23.33 19.23 0.35 0.37 0.36 0.28 0.33 0.18 0.36 0.263333333 20.59 22.13 13.99 22.04666667 18.90333333 0.738342203 -0.24944988 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030173///integral component of Golgi membrane+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex "GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding" GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006403///RNA localization+++GO:0006417///regulation of translation+++GO:0006486///protein glycosylation+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0017148///negative regulation of translation+++GO:0019276///UDP-N-acetylgalactosamine metabolic process+++GO:0022013///pallium cell proliferation in forebrain+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030259///lipid glycosylation+++GO:0051028///mRNA transport+++GO:0051252///regulation of RNA metabolic process+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0097150///neuronal stem cell population maintenance+++GO:0140059///dendrite arborization 14423 14423 'Galnt1' mRNA 606 707 552 8.4 9.6 8.12 9.7 10.26 11.02 8.706666667 10.32666667 809 833 887 621.6666667 843 8.69E-05 0.431643923 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine 14425 14425 'Galnt3' mRNA 1325 1427 1004 19.5 20.66 15.67 9.46 16.34 12.93 18.61 12.91 740 1248 979 1252 989 0.266053793 -0.339467705 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0007283///spermatogenesis+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine 14426 14426 'Galnt4' mRNA 277 298 345 2.89 3.06 3.82 5.11 4.89 5.51 3.256666667 5.17 564 527 589 306.6666667 560 1.23E-09 0.852427921 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine 14428 14428 'Galr2' mRNA 14.58 15.88 14.25 0.29 0.32 0.32 0.29 0.23 0.1 0.31 0.206666667 17.51 13.92 4.57 14.90333333 12 0.715774043 -0.354673101 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004966///galanin receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0031175///neuron projection development+++GO:0043647///inositol phosphate metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046488///phosphatidylinositol metabolic process+++GO:0090663///galanin-activated signaling pathway+++GO:1902608///positive regulation of large conductance calcium-activated potassium channel activity 14430 14430 'Galt' mRNA 869 852 813 27.81 26.78 27.96 25.87 27.18 25.47 27.51666667 26.17333333 943 969 895 844.6666667 935.6666667 0.191532925 0.136579393 00052///Galactose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars+++04917///Prolactin signaling pathway GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0008108///UDP-glucose:hexose-1-phosphate uridylyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0005975///carbohydrate metabolic process+++GO:0006011///UDP-glucose metabolic process+++GO:0006012///galactose metabolic process+++GO:0006258///UDP-glucose catabolic process+++GO:0033499///galactose catabolic process via UDP-galactose+++GO:0061623///glycolytic process from galactose 14431 14431 'Gamt' mRNA 352 343 305 22.8 21.98 20.95 22.71 22.93 21.14 21.91 22.26 402 395 362 333.3333333 386.3333333 0.176776449 0.202880135 "00260///Glycine, serine and threonine metabolism+++00330///Arginine and proline metabolism" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005902///microvillus+++GO:0042995///cell projection GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0030731///guanidinoacetate N-methyltransferase activity+++GO:0042802///identical protein binding GO:0006601///creatine biosynthetic process+++GO:0007283///spermatogenesis+++GO:0009887///animal organ morphogenesis+++GO:0032259///methylation+++GO:0040014///regulation of multicellular organism growth+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0046500///S-adenosylmethionine metabolic process 14432 14432 'Gap43' mRNA 7 11 8 0.32 0.5 0.39 0.4 0.25 0.46 0.403333333 0.37 10 6 11 8.666666667 9 0.972683379 0.043060334 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031527///filopodium membrane+++GO:0032584///growth cone membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0071944///cell periphery+++GO:0098982///GABA-ergic synapse GO:0001786///phosphatidylserine binding+++GO:0005516///calmodulin binding+++GO:0035727///lysophosphatidic acid binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0010001///glial cell differentiation+++GO:0016198///axon choice point recognition+++GO:0030154///cell differentiation+++GO:0031103///axon regeneration+++GO:0040008///regulation of growth+++GO:0042246///tissue regeneration+++GO:0045165///cell fate commitment+++GO:0051489///regulation of filopodium assembly+++GO:0099150///regulation of postsynaptic specialization assembly 14433 14433 'Gapdh' mRNA 40128.11 39597.97 38249.44 1781.26 1729.73 1800.42 1948.65 1829.1 2001.28 1770.47 1926.343333 50524.15 46261.11 50302.35 39325.17333 49029.20333 7.66E-10 0.305817059 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway+++05010///Alzheimer disease+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05415///Diabetic cardiomyopathy "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0031906///late endosome lumen+++GO:0031965///nuclear membrane+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097452///GAIT complex+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component+++GO:1990904///ribonucleoprotein complex" "GO:0000166///nucleotide binding+++GO:0004365///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016740///transferase activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0019899///enzyme binding+++GO:0035605///peptidyl-cysteine S-nitrosylase activity+++GO:0042802///identical protein binding+++GO:0050661///NADP binding+++GO:0051287///NAD binding+++GO:0097718///disordered domain specific binding" GO:0000226///microtubule cytoskeleton organization+++GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0010951///negative regulation of endopeptidase activity+++GO:0017148///negative regulation of translation+++GO:0019933///cAMP-mediated signaling+++GO:0031640///killing of cells of other organism+++GO:0032481///positive regulation of type I interferon production+++GO:0035606///peptidyl-cysteine S-trans-nitrosylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0050821///protein stabilization+++GO:0050832///defense response to fungus+++GO:0051402///neuron apoptotic process+++GO:0051873///killing by host of symbiont cells+++GO:0060359///response to ammonium ion+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071346///cellular response to interferon-gamma+++GO:1905460///negative regulation of vascular associated smooth muscle cell apoptotic process 14447 14447 'Gapdhs' mRNA 4 4 6 0.16 0.16 0.26 0.1 0.11 0.07 0.193333333 0.093333333 3 3 2 4.666666667 2.666666667 0.597214093 -0.829143412 00010///Glycolysis / Gluconeogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0097228///sperm principal piece "GO:0004365///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0050661///NADP binding+++GO:0051287///NAD binding" GO:0006006///glucose metabolic process+++GO:0006096///glycolytic process+++GO:0030317///flagellated sperm motility+++GO:0045821///positive regulation of glycolytic process 14450 14450 'Gart' mRNA 1278 1364 1351 20.8 21.83 23.34 17.13 14.86 15.51 21.99 15.83333333 1209 1025 1059 1331 1097.666667 0.001888695 -0.292381903 00230///Purine metabolism+++00670///One carbon pool by folate+++01523///Antifolate resistance GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004637///phosphoribosylamine-glycine ligase activity+++GO:0004641///phosphoribosylformylglycinamidine cyclo-ligase activity+++GO:0004644///phosphoribosylglycinamide formyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016742///hydroxymethyl-, formyl- and related transferase activity+++GO:0016874///ligase activity+++GO:0046872///metal ion binding" GO:0003360///brainstem development+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006544///glycine metabolic process+++GO:0008152///metabolic process+++GO:0009058///biosynthetic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0021549///cerebellum development+++GO:0021987///cerebral cortex development+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0046084///adenine biosynthetic process+++GO:0046654///tetrahydrofolate biosynthetic process+++GO:0097294///'de novo' XMP biosynthetic process 14451 14451 'Gas1' mRNA 10326 10461 2222 180.63 180.06 41.23 37.06 55.74 67.71 133.9733333 53.50333333 2438 3581 4313 7669.666667 3444 0.133450816 -1.13394224 04340///Hedgehog signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0005515///protein binding GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007411///axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009953///dorsal/ventral pattern formation+++GO:0010955///negative regulation of protein processing+++GO:0012501///programmed cell death+++GO:0021587///cerebellum morphogenesis+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0030308///negative regulation of cell growth+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0042473///outer ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042476///odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0045165///cell fate commitment+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0048589///developmental growth+++GO:0048592///eye morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0060021///roof of mouth development+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 14453 14453 'Gas2' mRNA 15610.46 16239.06 15784 359.04 368.6 386.18 185.91 185.42 188.35 371.2733333 186.56 9299 8978 9044.3 15877.84 9107.1 1.65E-56 -0.814580246 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005884///actin filament+++GO:0016020///membrane GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0001544///initiation of primordial ovarian follicle growth+++GO:0001547///antral ovarian follicle growth+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008360///regulation of cell shape+++GO:0008593///regulation of Notch signaling pathway+++GO:0030728///ovulation+++GO:0051726///regulation of cell cycle+++GO:0051764///actin crosslink formation+++GO:0071711///basement membrane organization 14456 14456 'Gas6' mRNA 3453 3632 3433 73.97 76.59 78.01 143.41 140.12 143.79 76.19 142.44 7701 7348 7476 3506 7508.333333 1.92E-90 1.086696813 01521///EGFR tyrosine kinase inhibitor resistance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm "GO:0001786///phosphatidylserine binding+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0030674///protein binding, bridging+++GO:0030971///receptor tyrosine kinase binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0048018///receptor ligand activity" "GO:0001764///neuron migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0003104///positive regulation of glomerular filtration+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007596///blood coagulation+++GO:0009267///cellular response to starvation+++GO:0010628///positive regulation of gene expression+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010934///macrophage cytokine production+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0019079///viral genome replication+++GO:0031100///animal organ regeneration+++GO:0031589///cell-substrate adhesion+++GO:0032008///positive regulation of TOR signaling+++GO:0032148///activation of protein kinase B activity+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035457///cellular response to interferon-alpha+++GO:0035690///cellular response to drug+++GO:0035754///B cell chemotaxis+++GO:0040008///regulation of growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043277///apoptotic cell clearance+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043491///protein kinase B signaling+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046718///viral entry into host cell+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0046827///positive regulation of protein export from nucleus+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050766///positive regulation of phagocytosis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070168///negative regulation of biomineral tissue development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0071307///cellular response to vitamin K+++GO:0071333///cellular response to glucose stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0085029///extracellular matrix assembly+++GO:0097028///dendritic cell differentiation+++GO:0097241///hematopoietic stem cell migration to bone marrow+++GO:1900142///negative regulation of oligodendrocyte apoptotic process+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:2000533///negative regulation of renal albumin absorption+++GO:2000669///negative regulation of dendritic cell apoptotic process" 14457 14457 'Gas7' mRNA 2100 1953 2049 16.19 14.83 16.75 24.76 21.62 22.73 15.92333333 23.03666667 3819 3275 3405 2034 3499.666667 4.44E-25 0.768416308 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008360///regulation of cell shape+++GO:0030041///actin filament polymerization+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0051017///actin filament bundle assembly 14459 14459 'Gast' mRNA 1 0 0 0.19 0 0 0.34 0 0.18 0.063333333 0.173333333 2 0 1 0.333333333 1 0.736887967 1.452215211 04971///Gastric acid secretion GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032094///response to food 14460 14460 'Gata1' mRNA 3 3 1 0.09 0.09 0.03 0.05 0 0 0.07 0.016666667 2 0 0 2.333333333 0.666666667 0.492448657 -1.820487285 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008301///DNA binding, bending+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0010559///regulation of glycoprotein biosynthetic process+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0010725///regulation of primitive erythrocyte differentiation+++GO:0030099///myeloid cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030220///platelet formation+++GO:0030221///basophil differentiation+++GO:0030222///eosinophil differentiation+++GO:0030502///negative regulation of bone mineralization+++GO:0031100///animal organ regeneration+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0035162///embryonic hemopoiesis+++GO:0035854///eosinophil fate commitment+++GO:0043066///negative regulation of apoptotic process+++GO:0043306///positive regulation of mast cell degranulation+++GO:0045165///cell fate commitment+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0048821///erythrocyte development+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0070527///platelet aggregation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0097028///dendritic cell differentiation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 14461 14461 'Gata2' mRNA 2799 2756 1247 47.33 45.85 22.37 21.87 34.56 30.69 38.51666667 29.04 1489 2296 2022 2267.333333 1935.666667 0.68112144 -0.218013853 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001655///urogenital system development+++GO:0001709///cell fate determination+++GO:0001764///neuron migration+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006909///phagocytosis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010725///regulation of primitive erythrocyte differentiation+++GO:0021514///ventral spinal cord interneuron differentiation+++GO:0021533///cell differentiation in hindbrain+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0021954///central nervous system neuron development+++GO:0021983///pituitary gland development+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0033993///response to lipid+++GO:0035019///somatic stem cell population maintenance+++GO:0035065///regulation of histone acetylation+++GO:0035854///eosinophil fate commitment+++GO:0042472///inner ear morphogenesis+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045165///cell fate commitment+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045650///negative regulation of macrophage differentiation+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048663///neuron fate commitment+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050766///positive regulation of phagocytosis+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0060216///definitive hemopoiesis+++GO:0060872///semicircular canal development+++GO:0061042///vascular wound healing+++GO:0070345///negative regulation of fat cell proliferation+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090102///cochlea development+++GO:0097154///GABAergic neuron differentiation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000977///regulation of forebrain neuron differentiation" 14462 14462 'Gata3' mRNA 624 623 650 10.61 10.43 11.7 5.62 5.43 5.11 10.91333333 5.386666667 381 359 335 632.3333333 358.3333333 4.99E-12 -0.833383691 "04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04928///Parathyroid hormone synthesis, secretion and action+++05321///Inflammatory bowel disease" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005134///interleukin-2 receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070888///E-box binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001709///cell fate determination+++GO:0001764///neuron migration+++GO:0001775///cell activation+++GO:0001806///type IV hypersensitivity+++GO:0001817///regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0002088///lens development in camera-type eye+++GO:0002376///immune system process+++GO:0002520///immune system development+++GO:0002572///pro-T cell differentiation+++GO:0003180///aortic valve morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003281///ventricular septum development+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009615///response to virus+++GO:0009791///post-embryonic development+++GO:0009967///positive regulation of signal transduction+++GO:0010332///response to gamma radiation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010975///regulation of neuron projection development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0030182///neuron differentiation+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0031929///TOR signaling+++GO:0032609///interferon-gamma production+++GO:0032633///interleukin-4 production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0033077///T cell differentiation in thymus+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0035162///embryonic hemopoiesis+++GO:0035457///cellular response to interferon-alpha+++GO:0035799///ureter maturation+++GO:0035898///parathyroid hormone secretion+++GO:0042421///norepinephrine biosynthetic process+++GO:0042472///inner ear morphogenesis+++GO:0042493///response to drug+++GO:0043370///regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043523///regulation of neuron apoptotic process+++GO:0043583///ear development+++GO:0043627///response to estrogen+++GO:0045061///thymic T cell selection+++GO:0045064///T-helper 2 cell differentiation+++GO:0045087///innate immune response+++GO:0045165///cell fate commitment+++GO:0045471///response to ethanol+++GO:0045582///positive regulation of T cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048485///sympathetic nervous system development+++GO:0048538///thymus development+++GO:0048568///embryonic organ development+++GO:0048589///developmental growth+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050728///negative regulation of inflammatory response+++GO:0050852///T cell receptor signaling pathway+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060017///parathyroid gland development+++GO:0060037///pharyngeal system development+++GO:0060065///uterus development+++GO:0060231///mesenchymal to epithelial transition+++GO:0060374///mast cell differentiation+++GO:0060676///ureteric bud formation+++GO:0061085///regulation of histone H3-K27 methylation+++GO:0061290///canonical Wnt signaling pathway involved in metanephric kidney development+++GO:0071345///cellular response to cytokine stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:0071599///otic vesicle development+++GO:0071773///cellular response to BMP stimulus+++GO:0072107///positive regulation of ureteric bud formation+++GO:0072178///nephric duct morphogenesis+++GO:0072179///nephric duct formation+++GO:0072182///regulation of nephron tubule epithelial cell differentiation+++GO:0072197///ureter morphogenesis+++GO:0072676///lymphocyte migration+++GO:0090102///cochlea development+++GO:1901536///negative regulation of DNA demethylation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000114///regulation of establishment of cell polarity+++GO:2000146///negative regulation of cell motility+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:2000607///negative regulation of cell proliferation involved in mesonephros development+++GO:2000611///positive regulation of thyroid hormone generation+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2000683///regulation of cellular response to X-ray+++GO:2000703///negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation+++GO:2000734///negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation" 14465 14465 'Gata6' mRNA 2 1 0 0.04 0.02 0 0.06 0 0 0.02 0.02 4 0 0 1 1.333333333 0.903678305 0.403242219 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0031965///nuclear membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0001949///sebaceous gland cell differentiation+++GO:0002759///regulation of antimicrobial humoral response+++GO:0003148///outflow tract septum morphogenesis+++GO:0003163///sinoatrial node development+++GO:0003309///type B pancreatic cell differentiation+++GO:0003310///pancreatic A cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006644///phospholipid metabolic process+++GO:0007493///endodermal cell fate determination+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0031016///pancreas development+++GO:0032526///response to retinoic acid+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0035239///tube morphogenesis+++GO:0035987///endodermal cell differentiation+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043627///response to estrogen+++GO:0045165///cell fate commitment+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048645///animal organ formation+++GO:0048738///cardiac muscle tissue development+++GO:0051145///smooth muscle cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0051891///positive regulation of cardioblast differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060047///heart contraction+++GO:0060430///lung saccule development+++GO:0060486///Clara cell differentiation+++GO:0060510///type II pneumocyte differentiation+++GO:0060575///intestinal epithelial cell differentiation+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0070848///response to growth factor+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071773///cellular response to BMP stimulus+++GO:0098773///skin epidermis development+++GO:0110024///positive regulation of cardiac muscle myoblast proliferation+++GO:1901390///positive regulation of transforming growth factor beta activation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904003///negative regulation of sebum secreting cell proliferation" 14466 14466 'Gba' mRNA 975 950 1099 27.96 26.81 33.31 64.13 68.69 68.54 29.36 67.12 2579 2700 2660 1008 2646.333333 1.35E-52 1.377463706 00511///Other glycan degradation+++00600///Sphingolipid metabolism+++04142///Lysosome GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0043202///lysosomal lumen "GO:0004348///glucosylceramidase activity+++GO:0005102///signaling receptor binding+++GO:0005124///scavenger receptor binding+++GO:0005515///protein binding+++GO:0008422///beta-glucosidase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046527///glucosyltransferase activity+++GO:0050295///steryl-beta-glucosidase activity" GO:0000423///mitophagy+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006678///glucosylceramide metabolic process+++GO:0006680///glucosylceramide catabolic process+++GO:0006914///autophagy+++GO:0007005///mitochondrion organization+++GO:0007040///lysosome organization+++GO:0007417///central nervous system development+++GO:0008152///metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008340///determination of adult lifespan+++GO:0009267///cellular response to starvation+++GO:0009268///response to pH+++GO:0014004///microglia differentiation+++GO:0019882///antigen processing and presentation+++GO:0019915///lipid storage+++GO:0021694///cerebellar Purkinje cell layer formation+++GO:0021859///pyramidal neuron differentiation+++GO:0022904///respiratory electron transport chain+++GO:0023021///termination of signal transduction+++GO:0030259///lipid glycosylation+++GO:0031333///negative regulation of protein complex assembly+++GO:0032006///regulation of TOR signaling+++GO:0032268///regulation of cellular protein metabolic process+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033077///T cell differentiation in thymus+++GO:0033561///regulation of water loss via skin+++GO:0033574///response to testosterone+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035745///T-helper 2 cell cytokine production+++GO:0042391///regulation of membrane potential+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043243///positive regulation of protein complex disassembly+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043589///skin morphogenesis+++GO:0043627///response to estrogen+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0048469///cell maturation+++GO:0048854///brain morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050877///nervous system process+++GO:0050905///neuromuscular process+++GO:0051246///regulation of protein metabolic process+++GO:0051247///positive regulation of protein metabolic process+++GO:0051402///neuron apoptotic process+++GO:0061518///microglial cell proliferation+++GO:0061744///motor behavior+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071425///hematopoietic stem cell proliferation+++GO:0071548///response to dexamethasone+++GO:0072676///lymphocyte migration+++GO:0097066///response to thyroid hormone+++GO:1901215///negative regulation of neuron death+++GO:1901805///beta-glucoside catabolic process+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:1903061///positive regulation of protein lipidation+++GO:1904457///positive regulation of neuronal action potential+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization+++GO:1905037///autophagosome organization 14467 14467 'Nipsnap2' mRNA 2306 2242 2432 62.26 59.63 69.66 58.38 58.21 60.14 63.85 58.91 2486 2420 2479 2326.666667 2461.666667 0.485276255 0.066923202 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0006119///oxidative phosphorylation+++GO:0007005///mitochondrion organization+++GO:1901843///positive regulation of high voltage-gated calcium channel activity 14468 14468 'Gbp2b' mRNA 8 21 22 0.16 0.4 0.58 0.61 0.88 0.75 0.38 0.746666667 28 50 43.01 17 40.33666667 0.024414294 1.232913476 04621///NOD-like receptor signaling pathway GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019002///GMP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0002376///immune system process+++GO:0034504///protein localization to nucleus+++GO:0035458///cellular response to interferon-beta+++GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051607///defense response to virus+++GO:0071346///cellular response to interferon-gamma 14469 14469 'Gbp2' mRNA 382 403 364 8.68 9.02 8.78 29.41 28.76 29.43 8.826666667 29.2 1488 1421 1441.99 383 1450.33 2.99E-98 1.909728954 04621///NOD-like receptor signaling pathway GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012506///vesicle membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0019899///enzyme binding+++GO:0019955///cytokine binding+++GO:0030507///spectrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051879///Hsp90 protein binding GO:0009617///response to bacterium+++GO:0034504///protein localization to nucleus+++GO:0035458///cellular response to interferon-beta+++GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma 14470 14470 'Rabac1' mRNA 6384 6589 6528 483.44 494.08 524.58 400.44 422.74 399.53 500.7 407.57 6057 6229 5837 6500.333333 6041 0.08160832 -0.118207873 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding 14472 14472 'Gbx2' mRNA 122 116.96 93.98 3.25 3.07 2.65 0.19 0.31 0.17 2.99 0.223333333 8 13 7 110.98 9.333333333 8.54E-19 -3.569131171 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001755///neural crest cell migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007411///axon guidance+++GO:0021549///cerebellum development+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0021568///rhombomere 2 development+++GO:0021794///thalamus development+++GO:0021884///forebrain neuron development+++GO:0021930///cerebellar granule cell precursor proliferation+++GO:0030902///hindbrain development+++GO:0030917///midbrain-hindbrain boundary development+++GO:0035239///tube morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048483///autonomic nervous system development+++GO:0051960///regulation of nervous system development" 14479 14479 'Usp15' mRNA 1156 1221 1131 26.55 25.9 22.77 27.57 30.61 29.1 25.07333333 29.09333333 1382 1387 1334 1169.333333 1367.666667 0.01089948 0.214918938 04137///Mitophagy - animal GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003824///catalytic activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0061649///ubiquitin modification-dependent histone binding+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016579///protein deubiquitination+++GO:0030509///BMP signaling pathway+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0071108///protein K48-linked deubiquitination+++GO:1900246///positive regulation of RIG-I signaling pathway+++GO:1905035///negative regulation of antifungal innate immune response+++GO:1990167///protein K27-linked deubiquitination 14489 14489 'Mtpn' mRNA 5099 5428 5344 68.06 71.26 75.66 78.63 74.05 72.47 71.66 75.05 6781 6238 6053 5290.333333 6357.333333 1.34E-04 0.251335187 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008290///F-actin capping protein complex+++GO:0030424///axon+++GO:0048471///perinuclear region of cytoplasm GO:0043565///sequence-specific DNA binding GO:0006584///catecholamine metabolic process+++GO:0008361///regulation of cell size+++GO:0010557///positive regulation of macromolecule biosynthetic process+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0021707///cerebellar granule cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0043403///skeletal muscle tissue regeneration+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051146///striated muscle cell differentiation+++GO:0051247///positive regulation of protein metabolic process+++GO:0071260///cellular response to mechanical stimulus+++GO:2000812///regulation of barbed-end actin filament capping 14525 14525 'Gcsam' mRNA 0 1 0 0 0.02 0 0.1 0.18 0.15 0.006666667 0.143333333 7 12 10 0.333333333 9.666666667 0.004040564 4.746964153 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003779///actin binding+++GO:0019901///protein kinase binding+++GO:0045159///myosin II binding GO:0050855///regulation of B cell receptor signaling pathway+++GO:2000401///regulation of lymphocyte migration+++GO:2000402///negative regulation of lymphocyte migration 14526 14526 'Gcg' mRNA 13 29 24 0.75 1.65 1.46 17.62 18.9 16.21 1.286666667 17.57666667 352 368 313 22 344.3333333 5.07E-54 3.956873292 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04714///Thermogenesis+++04911///Insulin secretion+++04922///Glucagon signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen GO:0005179///hormone activity+++GO:0031767///gastric inhibitory polypeptide receptor binding+++GO:0031769///glucagon receptor binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010737///protein kinase A signaling+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0014823///response to activity+++GO:0032092///positive regulation of protein binding+++GO:0032099///negative regulation of appetite+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042593///glucose homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045860///positive regulation of protein kinase activity+++GO:0050796///regulation of insulin secretion+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090280///positive regulation of calcium ion import+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 14527 14527 'Gcgr' mRNA 0 1 0 0 0.03 0 0 0.02 0.19 0.01 0.07 0 1 7 0.333333333 2.666666667 0.301781711 2.893058755 04080///Neuroactive ligand-receptor interaction+++04922///Glucagon signaling pathway GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004967///glucagon receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding GO:0006887///exocytosis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0009267///cellular response to starvation+++GO:0009755///hormone-mediated signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0042593///glucose homeostasis+++GO:0042594///response to starvation+++GO:0070873///regulation of glycogen metabolic process+++GO:0071377///cellular response to glucagon stimulus 14528 14528 'Gch1' mRNA 101 81 24 2.01 1.59 0.51 2.28 6.36 5.34 1.37 4.66 132 359 299 68.66666667 263.3333333 0.007763742 1.960492704 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003924///GTPase activity+++GO:0003934///GTP cyclohydrolase I activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0030742///GTP-dependent protein binding+++GO:0031369///translation initiation factor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding "GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0008152///metabolic process+++GO:0008217///regulation of blood pressure+++GO:0010460///positive regulation of heart rate+++GO:0014916///regulation of lung blood pressure+++GO:0032496///response to lipopolysaccharide+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:0035998///7,8-dihydroneopterin 3'-triphosphate biosynthetic process+++GO:0042311///vasodilation+++GO:0042416///dopamine biosynthetic process+++GO:0042559///pteridine-containing compound biosynthetic process+++GO:0045776///negative regulation of blood pressure+++GO:0046654///tetrahydrofolate biosynthetic process+++GO:0048265///response to pain+++GO:0050884///neuromuscular process controlling posture+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051066///dihydrobiopterin metabolic process+++GO:0065003///protein-containing complex assembly+++GO:0071222///cellular response to lipopolysaccharide+++GO:1905627///regulation of serotonin biosynthetic process+++GO:2000121///regulation of removal of superoxide radicals" 14531 14531 'Gcm1' mRNA 5 1 4 0.14 0.03 0.12 0.02 0.05 0.08 0.096666667 0.05 1 2 3 3.333333333 2 0.705140992 -0.754197662 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0042063///gliogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060018///astrocyte fate commitment+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development" 14533 14533 'Bloc1s1' mRNA 1728 1774 1745 251.41 257.52 269.53 232.96 273.96 252.68 259.4866667 253.2 1824 2083 1905 1749 1937.333333 0.144720012 0.136413958 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031083///BLOC-1 complex+++GO:0099078///BORC complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0008089///anterograde axonal transport+++GO:0009060///aerobic respiration+++GO:0016197///endosomal transport+++GO:0018394///peptidyl-lysine acetylation+++GO:0031175///neuron projection development+++GO:0032418///lysosome localization+++GO:0048490///anterograde synaptic vesicle transport 14534 14534 'Kat2a' mRNA 962 978.01 841 16.75 16.6 15.47 16.69 15.85 15.88 16.27333333 16.14 1103 1015 1017.06 927.0033333 1045.02 0.090867062 0.162849217 04330///Notch signaling pathway+++04919///Thyroid hormone signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000123///histone acetyltransferase complex+++GO:0000124///SAGA complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0045252///oxoglutarate dehydrogenase complex+++GO:0072686///mitotic spindle "GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0008134///transcription factor binding+++GO:0010484///H3 histone acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019903///protein phosphatase binding+++GO:0042826///histone deacetylase binding+++GO:0043997///histone acetyltransferase activity (H4-K12 specific)+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0106078///histone succinyltransferase activity" "GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001843///neural tube closure+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007616///long-term memory+++GO:0008283///cell proliferation+++GO:0014070///response to organic cyclic compound+++GO:0016573///histone acetylation+++GO:0016578///histone deubiquitination+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0021537///telencephalon development+++GO:0022037///metencephalon development+++GO:0030901///midbrain development+++GO:0031346///positive regulation of cell projection organization+++GO:0031647///regulation of protein stability+++GO:0031667///response to nutrient levels+++GO:0035066///positive regulation of histone acetylation+++GO:0035264///multicellular organism growth+++GO:0043966///histone H3 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046600///negative regulation of centriole replication+++GO:0048167///regulation of synaptic plasticity+++GO:0048312///intracellular distribution of mitochondria+++GO:0050863///regulation of T cell activation+++GO:0060173///limb development+++GO:0061035///regulation of cartilage development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071929///alpha-tubulin acetylation+++GO:0106077///histone succinylation+++GO:1903010///regulation of bone development+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000036///regulation of stem cell population maintenance+++GO:2000727///positive regulation of cardiac muscle cell differentiation" 14536 14536 'Nr6a1' mRNA 492.27 433.85 403.87 4.05 3.56 3.61 1.77 1.48 1.57 3.74 1.606666667 246.58 196.86 211.99 443.33 218.4766667 1.66E-12 -1.035625326 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II" 14537 14537 'Gcnt1' mRNA 1287 1439 1333 14.88 16.39 16.35 7.75 6.63 7.97 15.87333333 7.45 776 651 775 1353 734 6.09E-21 -0.895130453 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031985///Golgi cisterna "GO:0003829///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0009101///glycoprotein biosynthetic process+++GO:0032868///response to insulin+++GO:0048729///tissue morphogenesis+++GO:0050901///leukocyte tethering or rolling+++GO:0060352///cell adhesion molecule production+++GO:0060993///kidney morphogenesis 14538 14538 'Gcnt2' mRNA 524 548 496 6.68 6.91 6.73 8.09 7.46 6.78 6.773333333 7.443333333 717 646 585 522.6666667 649.3333333 0.011718652 0.301350038 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008109///N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0030335///positive regulation of cell migration+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0036438///maintenance of lens transparency+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 14539 14539 'Opn1mw' mRNA 17 22 19 0.85 1.09 1.01 0.17 0.27 0.14 0.983333333 0.193333333 4 6 3 19.33333333 4.333333333 0.005993297 -2.166886372 GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009584///detection of visible light+++GO:0018298///protein-chromophore linkage+++GO:0032467///positive regulation of cytokinesis+++GO:0050896///response to stimulus+++GO:0071482///cellular response to light stimulus 14544 14544 'Gda' mRNA 106 91 100 1.04 0.92 1.06 6.56 6.43 6.13 1.006666667 6.373333333 754 734 695 99 727.6666667 2.30E-89 2.865448465 00230///Purine metabolism GO:0005829///cytosol "GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008892///guanine deaminase activity+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0019239///deaminase activity+++GO:0046872///metal ion binding" GO:0000255///allantoin metabolic process+++GO:0006147///guanine catabolic process+++GO:0006161///deoxyguanosine catabolic process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0046038///GMP catabolic process+++GO:0046055///dGMP catabolic process+++GO:0046098///guanine metabolic process 14545 14545 'Gdap1' mRNA 462 394 427 6.34 5.28 6.2 0.51 0.49 0.92 5.94 0.64 43 40 76 427.6666667 53 5.93E-45 -3.024966375 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0000266///mitochondrial fission+++GO:0006626///protein targeting to mitochondrion+++GO:0006749///glutathione metabolic process+++GO:0008053///mitochondrial fusion+++GO:0032526///response to retinoic acid+++GO:0071305///cellular response to vitamin D 14547 14547 'Gdap2' mRNA 471 485 545 8.83 8.95 10.83 11.99 11.75 12.67 9.536666667 12.13666667 736 705 753 500.3333333 731.3333333 8.95E-06 0.53228906 GO:0003674///molecular_function GO:0032526///response to retinoic acid 14548 14548 'Mrps33' mRNA 1714 1715 1705 103.59 102.5 109.17 80.04 92.19 82.15 105.0866667 84.79333333 1525 1708 1512 1711.333333 1581.666667 0.193428925 -0.125116499 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function GO:0008150///biological_process 14555 14555 'Gpd1' mRNA 678 708 658 13.38 13.75 13.77 18.4 17.76 19.24 13.63333333 18.46666667 1073 1011 1086 681.3333333 1056.666667 9.59E-12 0.621668344 00564///Glycerophospholipid metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0009331///glycerol-3-phosphate dehydrogenase complex "GO:0004367///glycerol-3-phosphate dehydrogenase [NAD+] activity+++GO:0004368///glycerol-3-phosphate dehydrogenase (quinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042803///protein homodimerization activity+++GO:0051287///NAD binding" GO:0005975///carbohydrate metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006116///NADH oxidation+++GO:0006127///glycerophosphate shuttle+++GO:0006734///NADH metabolic process+++GO:0045821///positive regulation of glycolytic process+++GO:0046168///glycerol-3-phosphate catabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0071320///cellular response to cAMP+++GO:0071356///cellular response to tumor necrosis factor 14559 14559 'Gdf1' mRNA 3.26 17.61 21.68 0.14 0.74 0.97 0.67 0.42 0.2 0.616666667 0.43 18.01 10.98 5.18 14.18333333 11.39 0.752913831 -0.348201656 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0008083///growth factor activity GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0007492///endoderm development+++GO:0007498///mesoderm development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0060395///SMAD protein signal transduction 14560 14560 'Gdf10' mRNA 17 9 5 0.25 0.13 0.08 0.45 0.35 0.48 0.153333333 0.426666667 36 27 37 10.33333333 33.33333333 0.00472359 1.687007491 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008083///growth factor activity GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0007165///signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0045444///fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0060395///SMAD protein signal transduction 14561 14561 'Gdf11' mRNA 546 583 567 4.97 5.22 5.48 4.3 4.48 3.98 5.223333333 4.253333333 544 553 488 565.3333333 528.3333333 0.435222433 -0.109965404 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001501///skeletal system development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0021512///spinal cord anterior/posterior patterning+++GO:0031016///pancreas development+++GO:0045596///negative regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0048469///cell maturation+++GO:0048593///camera-type eye morphogenesis+++GO:0060021///roof of mouth development+++GO:0060395///SMAD protein signal transduction 14562 14562 'Gdf3' mRNA 5 0.91 3.03 0.21 0.02 0.11 1.57 1.57 1.63 0.113333333 1.59 49 56.15 50.24 2.98 51.79666667 7.16E-10 4.26322253 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019901///protein kinase binding GO:0001501///skeletal system development+++GO:0001654///eye development+++GO:0001701///in utero embryonic development+++GO:0002021///response to dietary excess+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0007498///mesoderm development+++GO:0010453///regulation of cell fate commitment+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030903///notochord development+++GO:0032525///somite rostral/caudal axis specification+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045605///negative regulation of epidermal cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0048859///formation of anatomical boundary+++GO:0060395///SMAD protein signal transduction+++GO:0090009///primitive streak formation 14563 14563 'Gdf5' mRNA 0 2 3 0 0.05 0.08 0.08 0.09 0.15 0.043333333 0.106666667 4 4 7 1.666666667 5 0.345583183 1.55750065 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0036122///BMP binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0009612///response to mechanical stimulus+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030326///embryonic limb morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0040014///regulation of multicellular organism growth+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043932///ossification involved in bone remodeling+++GO:0045666///positive regulation of neuron differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0060591///chondroblast differentiation+++GO:2001054///negative regulation of mesenchymal cell apoptotic process 14566 14566 'Gdf9' mRNA 24 21 35 0.83 0.86 1.48 0.53 0.82 0.9 1.056666667 0.75 15 23 24 26.66666667 20.66666667 0.552521008 -0.386917953 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0070698///type I activin receptor binding GO:0001555///oocyte growth+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0030509///BMP signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:2000870///regulation of progesterone secretion 14567 14567 'Gdi1' mRNA 7034 7367 6749 146.75 151.3 149.37 106.66 103.39 104.71 149.14 104.92 5881 5567 5590 7050 5679.333333 4.65E-10 -0.323245215 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030424///axon+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath GO:0005092///GDP-dissociation inhibitor activity+++GO:0005093///Rab GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032482///Rab protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045773///positive regulation of axon extension+++GO:0050771///negative regulation of axonogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051592///response to calcium ion+++GO:0090315///negative regulation of protein targeting to membrane 14569 14569 'Gdi2' mRNA 3609.88 3832.8 3845.96 74.59 77.95 84.29 128.76 126.46 132.01 78.94333333 129.0766667 7168.98 6876 7116 3762.88 7053.66 1.38E-46 0.893323312 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0005092///GDP-dissociation inhibitor activity+++GO:0005093///Rab GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 14570 14570 'Arhgdig' mRNA 69 49 46 4.24 2.98 3 2.57 2.64 2.55 3.406666667 2.586666667 48 48 46 54.66666667 47.33333333 0.628794481 -0.216209464 04722///Neurotrophin signaling pathway+++04962///Vasopressin-regulated water reabsorption GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005092///GDP-dissociation inhibitor activity+++GO:0005094///Rho GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity GO:0001835///blastocyst hatching+++GO:0007266///Rho protein signal transduction+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 14571 14571 'Gpd2' mRNA 2996 3142 2975 28.32 29.2 29.81 26.36 23.93 24.27 29.11 24.85333333 3210 2847 2863 3037.666667 2973.333333 0.613199339 -0.043686811 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0009331///glycerol-3-phosphate dehydrogenase complex+++GO:0016020///membrane GO:0004367///glycerol-3-phosphate dehydrogenase [NAD+] activity+++GO:0004368///glycerol-3-phosphate dehydrogenase (quinone) activity+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0052590///sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity+++GO:0052591///sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006734///NADH metabolic process+++GO:0019563///glycerol catabolic process+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development 14573 14573 'Gdnf' mRNA 10 13 18 0.16 0.19 0.3 0.15 0.22 0.2 0.216666667 0.19 11 17 15 13.66666667 14.33333333 0.956409616 0.050911286 04020///Calcium signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0043235///receptor complex GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity+++GO:0030116///glial cell-derived neurotrophic factor receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042803///protein homodimerization activity+++GO:0048018///receptor ligand activity GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001755///neural crest cell migration+++GO:0001759///organ induction+++GO:0001941///postsynaptic membrane organization+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007422///peripheral nervous system development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0021516///dorsal spinal cord development+++GO:0021784///postganglionic parasympathetic fiber development+++GO:0030182///neuron differentiation+++GO:0030432///peristalsis+++GO:0031175///neuron projection development+++GO:0032770///positive regulation of monooxygenase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048255///mRNA stabilization+++GO:0048484///enteric nervous system development+++GO:0048485///sympathetic nervous system development+++GO:0048568///embryonic organ development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051584///regulation of dopamine uptake involved in synaptic transmission+++GO:0060676///ureteric bud formation+++GO:0060688///regulation of morphogenesis of a branching structure+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071679///commissural neuron axon guidance+++GO:0072106///regulation of ureteric bud formation+++GO:0072107///positive regulation of ureteric bud formation+++GO:0072108///positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001260///regulation of semaphorin-plexin signaling pathway 14579 14579 'Gem' mRNA 82 95 109 1.86 2.17 2.65 4.46 3.92 3.93 2.226666667 4.103333333 215 181 178 95.33333333 191.3333333 9.24E-06 0.987525193 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0000278///mitotic cell cycle+++GO:0007165///signal transduction+++GO:0051276///chromosome organization+++GO:0051310///metaphase plate congression+++GO:1901842///negative regulation of high voltage-gated calcium channel activity 14580 14580 'Gfap' mRNA 124 99 81 1.49 1.06 1.13 2.88 2.63 2.88 1.226666667 2.796666667 189 191 194 101.3333333 191.3333333 2.92E-05 0.910144603 04630///JAK-STAT signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0044297///cell body+++GO:0045111///intermediate filament cytoskeleton+++GO:0097386///glial cell projection+++GO:0097449///astrocyte projection+++GO:0097450///astrocyte end-foot+++GO:0098574///cytoplasmic side of lysosomal membrane GO:0005178///integrin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0042802///identical protein binding GO:0006886///intracellular protein transport+++GO:0009611///response to wounding+++GO:0010467///gene expression+++GO:0010625///positive regulation of Schwann cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0014002///astrocyte development+++GO:0030198///extracellular matrix organization+++GO:0031102///neuron projection regeneration+++GO:0045103///intermediate filament-based process+++GO:0045109///intermediate filament organization+++GO:0051580///regulation of neurotransmitter uptake+++GO:0060020///Bergmann glial cell differentiation+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060291///long-term synaptic potentiation+++GO:0070779///D-aspartate import across plasma membrane+++GO:1904714///regulation of chaperone-mediated autophagy 14581 14581 'Gfi1' mRNA 2652 2593 2362 55.07 53 52.14 4.64 4.77 4.56 53.40333333 4.656666667 255 258 243 2535.666667 252 0 -3.341124887 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0017053///transcriptional repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007638///mechanosensory behavior+++GO:0009996///negative regulation of cell fate specification+++GO:0010956///negative regulation of calcidiol 1-monooxygenase activity+++GO:0010977///negative regulation of neuron projection development+++GO:0030097///hemopoiesis+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0042660///positive regulation of cell fate specification+++GO:0045165///cell fate commitment+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0070105///positive regulation of interleukin-6-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide" 14582 14582 'Gfi1b' mRNA 0 0 1 0 0 0.04 0 0 0.09 0.013333333 0.03 0 0 3 0.333333333 1 0.749787559 1.475757224 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:1903706///regulation of hemopoiesis 14583 14583 'Gfpt1' mRNA 570 630 366 4.83 5.25 3.29 4.74 4.06 4.2 4.456666667 4.333333333 643 539 552 522 578 0.437892394 0.143904359 "00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars+++04931///Insulin resistance+++05415///Diabetic cardiomyopathy" GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity+++GO:0008483///transaminase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0097367///carbohydrate derivative binding GO:0006002///fructose 6-phosphate metabolic process+++GO:0006042///glucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006541///glutamine metabolic process+++GO:0032922///circadian regulation of gene expression+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0048511///rhythmic process+++GO:1901135///carbohydrate derivative metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process 14584 14584 'Gfpt2' mRNA 1024 1086 1137 18.94 19.98 22.44 19.01 18.84 18.07 20.45333333 18.64 1172 1138 1091 1082.333333 1133.666667 0.676795113 0.052513188 "00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars+++04931///Insulin resistance+++05415///Diabetic cardiomyopathy" GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0097367///carbohydrate derivative binding GO:0006002///fructose 6-phosphate metabolic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006541///glutamine metabolic process+++GO:1901135///carbohydrate derivative metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 14585 14585 'Gfra1' mRNA 1581 1670 1521 18.46 19.13 18.83 9.74 8.05 9.43 18.80666667 9.073333333 965 783 905 1590.666667 884.3333333 8.12E-23 -0.859316729 GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0098797///plasma membrane protein complex GO:0005030///neurotrophin receptor activity+++GO:0005178///integrin binding+++GO:0038023///signaling receptor activity GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0009653///anatomical structure morphogenesis+++GO:0016477///cell migration+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0038179///neurotrophin signaling pathway+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation 14586 14586 'Gfra2' mRNA 98 59 64 1.53 0.91 1.06 0.75 0.52 0.34 1.166666667 0.536666667 55 35 23 73.66666667 37.66666667 0.015288308 -0.982388503 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043235///receptor complex GO:0016167///glial cell-derived neurotrophic factor receptor activity+++GO:0038023///signaling receptor activity GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0033139///regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway 14587 14587 'Gfra3' mRNA 1 8 3 0.03 0.22 0.09 0.1 0.05 0.1 0.113333333 0.083333333 4 2 4 4 3.333333333 0.873516985 -0.266540171 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043235///receptor complex GO:0005515///protein binding+++GO:0008046///axon guidance receptor activity+++GO:0015026///coreceptor activity+++GO:0016167///glial cell-derived neurotrophic factor receptor activity+++GO:0038023///signaling receptor activity GO:0001764///neuron migration+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0048485///sympathetic nervous system development+++GO:0048666///neuron development 14588 14588 'Gfra4' mRNA 67 70 29 2.85 2.88 1.3 10.21 14.47 12.4 2.343333333 12.36 278 385 328 55.33333333 330.3333333 1.45E-25 2.581295986 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043235///receptor complex GO:0015026///coreceptor activity+++GO:0016167///glial cell-derived neurotrophic factor receptor activity+++GO:0038023///signaling receptor activity GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007399///nervous system development+++GO:0030279///negative regulation of ossification+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway 14590 14590 'Ggh' mRNA 917 1013 906 40.82 44.71 42.66 52.61 53.35 58.57 42.73 54.84333333 1346 1330 1448 945.3333333 1374.666667 1.07E-09 0.529627771 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors+++01523///Antifolate resistance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005773///vacuole+++GO:0005829///cytosol+++GO:0042470///melanosome GO:0008233///peptidase activity+++GO:0008242///omega peptidase activity+++GO:0016787///hydrolase activity+++GO:0034722///gamma-glutamyl-peptidase activity GO:0006508///proteolysis+++GO:0009410///response to xenobiotic stimulus+++GO:0010043///response to zinc ion+++GO:0032868///response to insulin+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0046900///tetrahydrofolylpolyglutamate metabolic process+++GO:0070500///poly-gamma-glutamate metabolic process 14593 14593 'Ggps1' mRNA 1184 1346 1255 15.43 16.96 17.84 13.04 12.37 13.84 16.74333333 13.08333333 1096 1072 1070 1261.666667 1079.333333 0.009903317 -0.237229912 00900///Terpenoid backbone biosynthesis GO:0005737///cytoplasm GO:0004161///dimethylallyltranstransferase activity+++GO:0004311///farnesyltranstransferase activity+++GO:0004337///geranyltranstransferase activity+++GO:0004659///prenyltransferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006720///isoprenoid metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0033384///geranyl diphosphate biosynthetic process+++GO:0033386///geranylgeranyl diphosphate biosynthetic process+++GO:0045337///farnesyl diphosphate biosynthetic process 14594 14594 'Ggta1' mRNA 342 327 339 5.23 4.94 5.49 12.52 12.57 12.17 5.22 12.42 944 910 895 336 916.3333333 2.63E-41 1.434695567 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0031982///vesicle+++GO:0031985///Golgi cisterna+++GO:0032580///Golgi cisterna membrane+++GO:0043025///neuronal cell body "GO:0004966///galanin receptor activity+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0031763///galanin receptor binding+++GO:0031764///type 1 galanin receptor binding+++GO:0031765///type 2 galanin receptor binding+++GO:0031766///type 3 galanin receptor binding+++GO:0046872///metal ion binding+++GO:0047276///N-acetyllactosaminide 3-alpha-galactosyltransferase activity" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006954///inflammatory response+++GO:0007218///neuropeptide signaling pathway+++GO:0007399///nervous system development+++GO:0007631///feeding behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0010737///protein kinase A signaling+++GO:0019933///cAMP-mediated signaling+++GO:0030259///lipid glycosylation+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0033580///protein galactosylation at cell surface+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:0051464///positive regulation of cortisol secretion+++GO:0051795///positive regulation of timing of catagen+++GO:1902608///positive regulation of large conductance calcium-activated potassium channel activity 14595 14595 'B4galt1' mRNA 1614 1423 1562 22.85 19.79 23.54 40.84 42.74 39.81 22.06 41.13 3300 3361 3119 1533 3260 4.11E-42 1.075110197 00052///Galactose metabolism+++00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000138///Golgi trans cisterna+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030057///desmosome+++GO:0030175///filopodium+++GO:0031526///brush border membrane+++GO:0032580///Golgi cisterna membrane+++GO:0042995///cell projection "GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0003945///N-acetyllactosamine synthase activity+++GO:0004461///lactose synthase activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0035250///UDP-galactosyltransferase activity+++GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding+++GO:0098638///laminin binding involved in cell-matrix adhesion" GO:0002064///epithelial cell development+++GO:0002526///acute inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0005989///lactose biosynthetic process+++GO:0006012///galactose metabolic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007339///binding of sperm to zona pellucida+++GO:0007341///penetration of zona pellucida+++GO:0008285///negative regulation of cell proliferation+++GO:0009101///glycoprotein biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0030198///extracellular matrix organization+++GO:0030879///mammary gland development+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0045136///development of secondary sexual characteristics+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050900///leukocyte migration+++GO:0051270///regulation of cellular component movement+++GO:0060046///regulation of acrosome reaction+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0060055///angiogenesis involved in wound healing+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0070085///glycosylation 14598 14598 'Ggt1' mRNA 37 42 36 0.95 1.11 1.03 1.62 1.3 0.9 1.03 1.273333333 70 55 38 38.33333333 54.33333333 0.252580543 0.490107465 00430///Taurine and hypotaurine metabolism+++00480///Glutathione metabolism+++00590///Arachidonic acid metabolism GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm "GO:0000048///peptidyltransferase activity+++GO:0002951///leukotriene-C(4) hydrolase+++GO:0008233///peptidase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016755///transferase activity, transferring amino-acyl groups+++GO:0016787///hydrolase activity+++GO:0036374///glutathione hydrolase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0103068///leukotriene C4 gamma-glutamyl transferase activity" GO:0002682///regulation of immune system process+++GO:0006412///translation+++GO:0006508///proteolysis+++GO:0006520///cellular amino acid metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006691///leukotriene metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006751///glutathione catabolic process+++GO:0007283///spermatogenesis+++GO:0019344///cysteine biosynthetic process+++GO:0031179///peptide modification+++GO:0031638///zymogen activation+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034612///response to tumor necrosis factor+++GO:0050727///regulation of inflammatory response+++GO:1901750///leukotriene D4 biosynthetic process 14599 14599 'Gh' mRNA 32 39 25 2.33 2.81 1.93 2.35 3.39 3.02 2.356666667 2.92 37 52 46 32 45 0.290085806 0.489403051 "04060///Cytokine-cytokine receptor interaction+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030141///secretory granule+++GO:0031982///vesicle+++GO:0062023///collagen-containing extracellular matrix+++GO:0070195///growth hormone receptor complex GO:0005131///growth hormone receptor binding+++GO:0005148///prolactin receptor binding+++GO:0005179///hormone activity+++GO:0008083///growth factor activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007405///neuroblast proliferation+++GO:0007565///female pregnancy+++GO:0009416///response to light stimulus+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0031667///response to nutrient levels+++GO:0032094///response to food+++GO:0032355///response to estradiol+++GO:0032869///cellular response to insulin stimulus+++GO:0033143///regulation of intracellular steroid hormone receptor signaling pathway+++GO:0034097///response to cytokine+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043434///response to peptide hormone+++GO:0045927///positive regulation of growth+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048286///lung alveolus development+++GO:0048513///animal organ development+++GO:0050769///positive regulation of neurogenesis+++GO:0060396///growth hormone receptor signaling pathway+++GO:0071469///cellular response to alkaline pH+++GO:0090031///positive regulation of steroid hormone biosynthetic process+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:1901215///negative regulation of neuron death 14600 14600 'Ghr' mRNA 727 722 691 13.86 14.37 15.58 8.04 9.74 7.45 14.60333333 8.41 418 502 397 713.3333333 439 7.95E-09 -0.710475789 "04060///Cytokine-cytokine receptor interaction+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0070195///growth hormone receptor complex GO:0004896///cytokine receptor activity+++GO:0004903///growth hormone receptor activity+++GO:0005515///protein binding+++GO:0017046///peptide hormone binding+++GO:0019838///growth factor binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019955///cytokine binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000187///activation of MAPK activity+++GO:0006897///endocytosis+++GO:0007259///JAK-STAT cascade+++GO:0009755///hormone-mediated signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019530///taurine metabolic process+++GO:0032094///response to food+++GO:0032355///response to estradiol+++GO:0032869///cellular response to insulin stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0040014///regulation of multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042445///hormone metabolic process+++GO:0042976///activation of Janus kinase activity+++GO:0043278///response to morphine+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045597///positive regulation of cell differentiation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051384///response to glucocorticoid+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0060396///growth hormone receptor signaling pathway+++GO:0070555///response to interleukin-1+++GO:1901215///negative regulation of neuron death 14601 14601 'Ghrh' mRNA 3.46 2.23 1.98 0.07 0.05 0.05 0.08 0.08 0.05 0.056666667 0.07 4.39 4.01 2.72 2.556666667 3.706666667 0.706410296 0.73603486 "04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0043679///axon terminus GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0005515///protein binding+++GO:0016608///growth hormone-releasing hormone activity+++GO:0031770///growth hormone-releasing hormone receptor binding+++GO:0051428///peptide hormone receptor binding "GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0021984///adenohypophysis development+++GO:0030252///growth hormone secretion+++GO:0032094///response to food+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042748///circadian sleep/wake cycle, non-REM sleep+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046887///positive regulation of hormone secretion+++GO:0060124///positive regulation of growth hormone secretion" 14602 14602 'Ghrhr' mRNA 1 0 0 0.04 0 0 0 0 0.03 0.013333333 0.01 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 "04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action" GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0030141///secretory granule+++GO:0042383///sarcolemma GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016520///growth hormone-releasing hormone receptor activity+++GO:0017046///peptide hormone binding+++GO:0019838///growth factor binding "GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0019933///cAMP-mediated signaling+++GO:0021984///adenohypophysis development+++GO:0030104///water homeostasis+++GO:0030879///mammary gland development+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0033143///regulation of intracellular steroid hormone receptor signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042445///hormone metabolic process+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0043627///response to estrogen+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046887///positive regulation of hormone secretion+++GO:0048469///cell maturation+++GO:0051246///regulation of protein metabolic process+++GO:0051384///response to glucocorticoid+++GO:0060124///positive regulation of growth hormone secretion+++GO:0060133///somatotropin secreting cell development+++GO:0071333///cellular response to glucose stimulus" 14605 14605 'Tsc22d3' mRNA 3428 3614 3430 93.3 97.36 99.32 126.6 127.15 120.37 96.66 124.7066667 5445 5402 5067 3490.666667 5304.666667 1.09E-22 0.591868949 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0043426///MRF binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006970///response to osmotic stress+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0070236///negative regulation of activation-induced cell death of T cells 14608 14608 'Gpr83' mRNA 23 24 16 0.36 0.36 0.26 0.47 0.4 0.29 0.326666667 0.386666667 36 29 21 21 28.66666667 0.464033653 0.441209924 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097730///non-motile cilium GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity+++GO:0008188///neuropeptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0051384///response to glucocorticoid 14609 14609 'Gja1' mRNA 175 203 235 3.09 3.53 4.4 9.11 7.89 8.46 3.673333333 8.486666667 594 500 534 204.3333333 542.6666667 8.27E-20 1.391394872 04540///Gap junction+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005916///fascia adherens+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0014704///intercalated disc+++GO:0015934///large ribosomal subunit+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0031616///spindle pole centrosome+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043292///contractile fiber+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0070160///tight junction+++GO:1990904///ribonucleoprotein complex "GO:0001046///core promoter sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005243///gap junction channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0015075///ion transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0015631///tubulin binding+++GO:0017124///SH3 domain binding+++GO:0019843///rRNA binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding+++GO:0030957///Tat protein binding+++GO:0034634///glutathione transmembrane transporter activity+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043014///alpha-tubulin binding+++GO:0043023///ribosomal large subunit binding+++GO:0043024///ribosomal small subunit binding+++GO:0043422///protein kinase B binding+++GO:0047485///protein N-terminus binding+++GO:0048487///beta-tubulin binding+++GO:0051059///NF-kappaB binding+++GO:0051082///unfolded protein binding+++GO:0055077///gap junction hemi-channel activity+++GO:0071253///connexin binding+++GO:0086075///gap junction channel activity involved in cardiac conduction electrical coupling+++GO:0097110///scaffold protein binding+++GO:0097718///disordered domain specific binding+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling+++GO:1990782///protein tyrosine kinase binding" "GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000448///cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001558///regulation of cell growth+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001947///heart looping+++GO:0002070///epithelial cell maturation+++GO:0002088///lens development in camera-type eye+++GO:0002544///chronic inflammatory response+++GO:0002931///response to ischemia+++GO:0003104///positive regulation of glomerular filtration+++GO:0003158///endothelium development+++GO:0003294///atrial ventricular junction remodeling+++GO:0003300///cardiac muscle hypertrophy+++GO:0003347///epicardial cell to mesenchymal cell transition+++GO:0006281///DNA repair+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006407///rRNA export from nucleus+++GO:0006884///cell volume homeostasis+++GO:0006913///nucleocytoplasmic transport+++GO:0006915///apoptotic process+++GO:0007098///centrosome cycle+++GO:0007154///cell communication+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0007283///spermatogenesis+++GO:0007507///heart development+++GO:0007512///adult heart development+++GO:0007569///cell aging+++GO:0008016///regulation of heart contraction+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009268///response to pH+++GO:0009303///rRNA transcription+++GO:0009749///response to glucose+++GO:0010232///vascular transport+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010643///cell communication by chemical coupling+++GO:0010644///cell communication by electrical coupling+++GO:0010649///regulation of cell communication by electrical coupling+++GO:0010652///positive regulation of cell communication by chemical coupling+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010824///regulation of centrosome duplication+++GO:0010825///positive regulation of centrosome duplication+++GO:0010826///negative regulation of centrosome duplication+++GO:0014047///glutamate secretion+++GO:0015867///ATP transport+++GO:0019827///stem cell population maintenance+++GO:0022898///regulation of transmembrane transporter activity+++GO:0030308///negative regulation of cell growth+++GO:0030500///regulation of bone mineralization+++GO:0031328///positive regulation of cellular biosynthetic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032024///positive regulation of insulin secretion+++GO:0032071///regulation of endodeoxyribonuclease activity+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0034220///ion transmembrane transport+++GO:0034405///response to fluid shear stress+++GO:0034644///cellular response to UV+++GO:0034775///glutathione transmembrane transport+++GO:0035050///embryonic heart tube development+++GO:0035437///maintenance of protein localization in endoplasmic reticulum+++GO:0042098///T cell proliferation+++GO:0042110///T cell activation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042274///ribosomal small subunit biogenesis+++GO:0042311///vasodilation+++GO:0042733///embryonic digit morphogenesis+++GO:0042908///xenobiotic transport+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043403///skeletal muscle tissue regeneration+++GO:0043434///response to peptide hormone+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045216///cell-cell junction organization+++GO:0045727///positive regulation of translation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045740///positive regulation of DNA replication+++GO:0045844///positive regulation of striated muscle tissue development+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046599///regulation of centriole replication+++GO:0046697///decidualization+++GO:0046849///bone remodeling+++GO:0046850///regulation of bone remodeling+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0048514///blood vessel morphogenesis+++GO:0048812///neuron projection morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050821///protein stabilization+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0051924///regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060156///milk ejection reflex+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060312///regulation of blood vessel remodeling+++GO:0060348///bone development+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0060699///regulation of endoribonuclease activity+++GO:0060735///regulation of eIF2 alpha phosphorylation by dsRNA+++GO:0061045///negative regulation of wound healing+++GO:0061337///cardiac conduction+++GO:0071260///cellular response to mechanical stimulus+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071467///cellular response to pH+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0090162///establishment of epithelial cell polarity+++GO:0097421///liver regeneration+++GO:0099111///microtubule-based transport+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0140115///export across plasma membrane+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity+++GO:1902629///regulation of mRNA stability involved in cellular response to UV+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:1904646///cellular response to amyloid-beta+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:1905867///epididymis development+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000381///negative regulation of mesoderm development+++GO:2000810///regulation of bicellular tight junction assembly+++GO:2000987///positive regulation of behavioral fear response" 14611 14611 'Gja3' mRNA 0 2 2 0 0.04 0.04 0.07 0.15 0.26 0.026666667 0.16 4 8 14 1.333333333 8.666666667 0.051045219 2.688051108 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045121///membrane raft GO:0005243///gap junction channel activity+++GO:0042802///identical protein binding+++GO:0055077///gap junction hemi-channel activity GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007601///visual perception+++GO:0009268///response to pH+++GO:0042542///response to hydrogen peroxide+++GO:0055085///transmembrane transport+++GO:1990349///gap junction-mediated intercellular transport 14612 14612 'Gja4' mRNA 69 95 70 2.38 3.23 2.56 3.06 1.75 2.2 2.723333333 2.336666667 102 57 71 78 76.66666667 0.927185881 -0.037854988 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity GO:0001568///blood vessel development+++GO:0003158///endothelium development+++GO:0006816///calcium ion transport+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0048265///response to pain+++GO:0055085///transmembrane transport 14613 14613 'Gja5' mRNA 0 1 3 0 0.02 0.06 0.58 0.37 0.38 0.026666667 0.443333333 38 24 24 1.333333333 28.66666667 5.93E-06 4.399441277 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0005243///gap junction channel activity+++GO:0055077///gap junction hemi-channel activity+++GO:0071253///connexin binding+++GO:0086075///gap junction channel activity involved in cardiac conduction electrical coupling+++GO:0086076///gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling+++GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling+++GO:0086078///gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling+++GO:0097718///disordered domain specific binding GO:0001501///skeletal system development+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0003071///renal system process involved in regulation of systemic arterial blood pressure+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0003105///negative regulation of glomerular filtration+++GO:0003151///outflow tract morphogenesis+++GO:0003158///endothelium development+++GO:0003161///cardiac conduction system development+++GO:0003174///mitral valve development+++GO:0003193///pulmonary valve formation+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0003284///septum primum development+++GO:0003294///atrial ventricular junction remodeling+++GO:0006813///potassium ion transport+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007507///heart development+++GO:0007601///visual perception+++GO:0010643///cell communication by chemical coupling+++GO:0010644///cell communication by electrical coupling+++GO:0010649///regulation of cell communication by electrical coupling+++GO:0010652///positive regulation of cell communication by chemical coupling+++GO:0016264///gap junction assembly+++GO:0030326///embryonic limb morphogenesis+++GO:0035050///embryonic heart tube development+++GO:0035922///foramen ovale closure+++GO:0042311///vasodilation+++GO:0045776///negative regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0048844///artery morphogenesis+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0060412///ventricular septum morphogenesis+++GO:0060413///atrial septum morphogenesis+++GO:0061337///cardiac conduction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086015///SA node cell action potential+++GO:0086044///atrial cardiac muscle cell to AV node cell communication by electrical coupling+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:0086054///bundle of His cell to Purkinje myocyte communication by electrical coupling+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0086065///cell communication involved in cardiac conduction+++GO:0086067///AV node cell to bundle of His cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097746///regulation of blood vessel diameter+++GO:0098904///regulation of AV node cell action potential+++GO:0098905///regulation of bundle of His cell action potential+++GO:0098906///regulation of Purkinje myocyte action potential+++GO:0098910///regulation of atrial cardiac muscle cell action potential+++GO:1900133///regulation of renin secretion into blood stream+++GO:1900825///regulation of membrane depolarization during cardiac muscle cell action potential+++GO:1990029///vasomotion 14615 14615 'Gjc1' mRNA 64 65 42 1.78 1.78 1.21 2.04 1.87 1.88 1.59 1.93 82 78 78 57 79.33333333 0.158064919 0.472129158 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005216///ion channel activity+++GO:0005243///gap junction channel activity+++GO:0005515///protein binding+++GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling GO:0001570///vasculogenesis+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007268///chemical synaptic transmission+++GO:0007507///heart development+++GO:0007601///visual perception+++GO:0016264///gap junction assembly+++GO:0048468///cell development+++GO:0048738///cardiac muscle tissue development+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling 14616 14616 'Gja8' mRNA 4 1 5 0.03 0.01 0.04 0 0.03 0 0.026666667 0.01 0 4 0 3.333333333 1.333333333 0.553523141 -1.335973952 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity+++GO:0042802///identical protein binding GO:0002088///lens development in camera-type eye+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0043010///camera-type eye development+++GO:0055085///transmembrane transport+++GO:1990349///gap junction-mediated intercellular transport 14617 14617 'Gjd2' mRNA 10 10 7 0.19 0.19 0.14 0 0.02 0 0.173333333 0.006666667 0 1 0 9 0.333333333 0.00537405 -4.655605112 04540///Gap junction GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005243///gap junction channel activity+++GO:0005515///protein binding GO:0001508///action potential+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007268///chemical synaptic transmission+++GO:0007601///visual perception+++GO:0055085///transmembrane transport 14618 14618 'Gjb1' mRNA 819 811 698 30.22 29.42 27.22 20.38 18.45 19.31 28.95333333 19.38 633 565 586 776 594.6666667 1.63E-04 -0.393962795 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0005243///gap junction channel activity+++GO:0042802///identical protein binding GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0015868///purine ribonucleotide transport+++GO:0055085///transmembrane transport+++GO:1905867///epididymis development 14619 14619 'Gjb2' mRNA 23123 24051 20205 537.73 550.71 498.45 485.23 499.56 484.22 528.9633333 489.67 23998 24125 23184 22459.66667 23769 0.221312365 0.073231148 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0097449///astrocyte projection GO:0005243///gap junction channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling GO:0002931///response to ischemia+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0007605///sensory perception of sound+++GO:0010644///cell communication by electrical coupling+++GO:0016264///gap junction assembly+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0032570///response to progesterone+++GO:0034599///cellular response to oxidative stress+++GO:0044752///response to human chorionic gonadotropin+++GO:0046677///response to antibiotic+++GO:0046697///decidualization+++GO:0048839///inner ear development+++GO:0055085///transmembrane transport+++GO:0071377///cellular response to glucagon stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1905867///epididymis development+++GO:1990349///gap junction-mediated intercellular transport 14620 14620 'Gjb3' mRNA 1 0 0 0.04 0 0 0.87 1.19 1.3 0.013333333 1.12 32 36 42 0.333333333 36.66666667 6.77E-07 6.667141606 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0005243///gap junction channel activity+++GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007283///spermatogenesis+++GO:0043588///skin development+++GO:0055085///transmembrane transport+++GO:0071300///cellular response to retinoic acid 14621 14621 'Gjb4' mRNA 0 4 1 0 0.16 0.04 1.7 1.48 1.87 0.066666667 1.683333333 48 41 52 1.666666667 47 4.35E-09 4.810470939 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity+++GO:0005515///protein binding GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007608///sensory perception of smell+++GO:0042048///olfactory behavior+++GO:0055085///transmembrane transport+++GO:1990349///gap junction-mediated intercellular transport 14622 14622 'Gjb5' mRNA 0 2 0 0 0.07 0 0.18 0.21 0.15 0.023333333 0.18 6 7 5 0.666666667 6 0.074742326 3.17935257 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0055085///transmembrane transport+++GO:0060707///trophoblast giant cell differentiation+++GO:0060708///spongiotrophoblast differentiation+++GO:0060713///labyrinthine layer morphogenesis+++GO:1905867///epididymis development 14623 14623 'Gjb6' mRNA 19163 20302 19288 529.15 552.78 567.58 295.01 297.49 301.64 549.8366667 298.0466667 12235 12040 12102 19584.33333 12125.66667 1.10E-44 -0.703637648 GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0048487///beta-tubulin binding+++GO:0051015///actin filament binding+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling GO:0006915///apoptotic process+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007568///aging+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0010644///cell communication by electrical coupling+++GO:0016264///gap junction assembly+++GO:0032496///response to lipopolysaccharide+++GO:0042471///ear morphogenesis+++GO:0048839///inner ear development+++GO:0051602///response to electrical stimulus+++GO:0055085///transmembrane transport+++GO:0071333///cellular response to glucose stimulus+++GO:1990349///gap junction-mediated intercellular transport 14625 14625 'Gykl1' mRNA 3 1 2 0.09 0.03 0.06 0.03 0 0 0.06 0.01 1 0 0 2 0.333333333 0.375343153 -2.496394607 00561///Glycerolipid metabolism+++03320///PPAR signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0019563///glycerol catabolic process+++GO:0046167///glycerol-3-phosphate biosynthetic process 14626 14626 'Gk2' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00561///Glycerolipid metabolism+++03320///PPAR signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0016310///phosphorylation+++GO:0019563///glycerol catabolic process+++GO:0046167///glycerol-3-phosphate biosynthetic process 14628 14628 'Ostm1' mRNA 939 879 1061 17.14 15.79 20.54 26.35 24.75 25.95 17.82333333 25.68333333 1661 1524 1584 959.6666667 1589.666667 2.28E-12 0.711040088 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0030316///osteoclast differentiation 14629 14629 'Gclc' mRNA 308 320 290 5.39 5.48 5.38 4.27 3.77 3.7 5.416666667 3.913333333 280 241 237 306 252.6666667 0.077740879 -0.288152683 00270///Cysteine and methionine metabolism+++00480///Glutathione metabolism+++01240///Biosynthesis of cofactors+++04212///Longevity regulating pathway - worm+++04216///Ferroptosis GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0017109///glutamate-cysteine ligase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004357///glutamate-cysteine ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016595///glutamate binding+++GO:0016874///ligase activity+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding "GO:0006534///cysteine metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009408///response to heat+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0014823///response to activity+++GO:0019852///L-ascorbic acid metabolic process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0044752///response to human chorionic gonadotropin+++GO:0045454///cell redox homeostasis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046685///response to arsenic-containing substance+++GO:0046686///response to cadmium ion+++GO:0051409///response to nitrosative stress+++GO:0051900///regulation of mitochondrial depolarization+++GO:0070555///response to interleukin-1+++GO:0071260///cellular response to mechanical stimulus+++GO:0071333///cellular response to glucose stimulus+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0097069///cellular response to thyroxine stimulus+++GO:0097746///regulation of blood vessel diameter+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:2000490///negative regulation of hepatic stellate cell activation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 14630 14630 'Gclm' mRNA 510 577 113 13.96 15.56 3.28 5.5 7.63 10.06 10.93333333 7.73 231 313 409 400 317.6666667 0.746125588 -0.311381485 00270///Cysteine and methionine metabolism+++00480///Glutathione metabolism+++01240///Biosynthesis of cofactors+++04216///Ferroptosis GO:0017109///glutamate-cysteine ligase complex GO:0004357///glutamate-cysteine ligase activity+++GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0035226///glutamate-cysteine ligase catalytic subunit binding+++GO:0044877///protein-containing complex binding+++GO:0047834///D-threo-aldose 1-dehydrogenase activity GO:0006534///cysteine metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0008637///apoptotic mitochondrial changes+++GO:0009410///response to xenobiotic stimulus+++GO:0014823///response to activity+++GO:0035229///positive regulation of glutamate-cysteine ligase activity+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035733///hepatic stellate cell activation+++GO:0042493///response to drug+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0044752///response to human chorionic gonadotropin+++GO:0051409///response to nitrosative stress+++GO:0051900///regulation of mitochondrial depolarization+++GO:0071333///cellular response to glucose stimulus+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0097069///cellular response to thyroxine stimulus+++GO:0097746///regulation of blood vessel diameter+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 14632 14632 'Gli1' mRNA 42 43 30 0.62 0.63 0.47 1.12 0.65 0.73 0.573333333 0.833333333 87 49 55 38.33333333 63.66666667 0.068915078 0.720908938 04024///cAMP signaling pathway+++04340///Hedgehog signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005930///axoneme "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007418///ventral midline development+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009913///epidermal cell differentiation+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0021696///cerebellar cortex morphogenesis+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030850///prostate gland development+++GO:0045667///regulation of osteoblast differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060032///notochord regression+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060070///canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097421///liver regeneration+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:2000345///regulation of hepatocyte proliferation" 14633 14633 'Gli2' mRNA 146 194 108 1.12 1.5 0.91 1.04 0.93 0.75 1.176666667 0.906666667 155 136 108 149.3333333 133 0.580537939 -0.170916137 04340///Hedgehog signaling pathway+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097542///ciliary tip "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0002009///morphogenesis of an epithelium+++GO:0002062///chondrocyte differentiation+++GO:0002076///osteoblast development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007411///axon guidance+++GO:0007418///ventral midline development+++GO:0007442///hindgut morphogenesis+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0009913///epidermal cell differentiation+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0021508///floor plate formation+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021517///ventral spinal cord development+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021696///cerebellar cortex morphogenesis+++GO:0021775///smoothened signaling pathway involved in ventral spinal cord interneuron specification+++GO:0021776///smoothened signaling pathway involved in spinal cord motor neuron cell fate specification+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021915///neural tube development+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030879///mammary gland development+++GO:0030902///hindbrain development+++GO:0031069///hair follicle morphogenesis+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0035295///tube development+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048566///embryonic digestive tract development+++GO:0048589///developmental growth+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048666///neuron development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048856///anatomical structure development+++GO:0060032///notochord regression+++GO:0060322///head development+++GO:0060513///prostatic bud formation+++GO:0060603///mammary gland duct morphogenesis+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0071407///cellular response to organic cyclic compound+++GO:0090103///cochlea morphogenesis+++GO:0098586///cellular response to virus+++GO:1901620///regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning" 14634 14634 'Gli3' mRNA 201 247 134 1.25 1.51 0.96 1.67 1.59 1.6 1.24 1.62 284 267 284 194 278.3333333 0.010792316 0.518809574 04024///cAMP signaling pathway+++04340///Hedgehog signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0017053///transcriptional repressor complex+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0035035///histone acetyltransferase binding+++GO:0036033///mediator complex binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007389///pattern specification process+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007442///hindgut morphogenesis+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0010468///regulation of gene expression+++GO:0016485///protein processing+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021537///telencephalon development+++GO:0021543///pallium development+++GO:0021544///subpallium development+++GO:0021631///optic nerve morphogenesis+++GO:0021766///hippocampus development+++GO:0021775///smoothened signaling pathway involved in ventral spinal cord interneuron specification+++GO:0021776///smoothened signaling pathway involved in spinal cord motor neuron cell fate specification+++GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0021801///cerebral cortex radial glia guided migration+++GO:0021819///layer formation in cerebral cortex+++GO:0021861///forebrain radial glial cell differentiation+++GO:0021915///neural tube development+++GO:0022018///lateral ganglionic eminence cell proliferation+++GO:0030318///melanocyte differentiation+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030850///prostate gland development+++GO:0030879///mammary gland development+++GO:0030900///forebrain development+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0035108///limb morphogenesis+++GO:0035295///tube development+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0043586///tongue development+++GO:0043627///response to estrogen+++GO:0045060///negative thymic T cell selection+++GO:0045595///regulation of cell differentiation+++GO:0045596///negative regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046639///negative regulation of alpha-beta T cell differentiation+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048566///embryonic digestive tract development+++GO:0048568///embryonic organ development+++GO:0048589///developmental growth+++GO:0048593///camera-type eye morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048663///neuron fate commitment+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048709///oligodendrocyte differentiation+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048839///inner ear development+++GO:0048856///anatomical structure development+++GO:0060021///roof of mouth development+++GO:0060173///limb development+++GO:0060364///frontal suture morphogenesis+++GO:0060366///lambdoid suture morphogenesis+++GO:0060367///sagittal suture morphogenesis+++GO:0060594///mammary gland specification+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0060840///artery development+++GO:0060873///anterior semicircular canal development+++GO:0060875///lateral semicircular canal development+++GO:0061005///cell differentiation involved in kidney development+++GO:0070242///thymocyte apoptotic process+++GO:0071625///vocalization behavior+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097421///liver regeneration+++GO:1901620///regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1903010///regulation of bone development" 14635 14635 'Galk1' mRNA 1982 1842 1854 77.72 71.24 77.13 60.35 61.54 60.02 75.36333333 60.63666667 1768 1759 1701 1892.666667 1742.666667 0.112340215 -0.131178427 00052///Galactose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0004335///galactokinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005534///galactose binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006012///galactose metabolic process+++GO:0016310///phosphorylation+++GO:0019402///galactitol metabolic process+++GO:0033499///galactose catabolic process via UDP-galactose+++GO:0046835///carbohydrate phosphorylation+++GO:0061623///glycolytic process from galactose 14645 14645 'Glul' mRNA 5724 5348 5235 112.56 103.51 109.2 83.86 83.92 85.17 108.4233333 84.31666667 4906 4795 4825 5435.666667 4842 0.003134177 -0.17845512 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00910///Nitrogen metabolism+++01230///Biosynthesis of amino acids+++04217///Necroptosis+++04724///Glutamatergic synapse+++04727///GABAergic synapse" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0044297///cell body+++GO:0097386///glial cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004356///glutamate-ammonia ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016595///glutamate binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0045503///dynein light chain binding+++GO:0046872///metal ion binding "GO:0001525///angiogenesis+++GO:0006536///glutamate metabolic process+++GO:0006542///glutamine biosynthetic process+++GO:0006807///nitrogen compound metabolic process+++GO:0008283///cell proliferation+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0010594///regulation of endothelial cell migration+++GO:0018345///protein palmitoylation+++GO:0019676///ammonia assimilation cycle+++GO:0032024///positive regulation of insulin secretion+++GO:0042254///ribosome biogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:1903670///regulation of sprouting angiogenesis+++GO:1904749///regulation of protein localization to nucleolus" 14651 14651 'Hagh' mRNA 1810.34 1770.4 1647.68 92.91 89.82 89.44 68.72 73.15 72.59 90.72333333 71.48666667 1536.42 1595.12 1577.76 1742.806667 1569.766667 0.043861264 -0.161113861 00620///Pyruvate metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004416///hydroxyacylglutathione hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0005975///carbohydrate metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0019243///methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione 14654 14654 'Glra1' mRNA 7 3 7 0.16 0.07 0.17 0 0.02 0.02 0.133333333 0.013333333 0 1 1 5.666666667 0.666666667 0.078790525 -3.103654569 04080///Neuroactive ligand-receptor interaction GO:0005622///intracellular+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098690///glycinergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008270///zinc ion binding+++GO:0016594///glycine binding+++GO:0016933///extracellularly glycine-gated ion channel activity+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0022824///transmitter-gated ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0030977///taurine binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001508///action potential+++GO:0001964///startle response+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007340///acrosome reaction+++GO:0007601///visual perception+++GO:0007628///adult walking behavior+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043200///response to amino acid+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0050877///nervous system process+++GO:0050884///neuromuscular process controlling posture+++GO:0050905///neuromuscular process+++GO:0051970///negative regulation of transmission of nerve impulse+++GO:0060012///synaptic transmission, glycinergic+++GO:0060013///righting reflex+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0071230///cellular response to amino acid stimulus+++GO:0071294///cellular response to zinc ion+++GO:0071361///cellular response to ethanol+++GO:0097305///response to alcohol+++GO:1902476///chloride transmembrane transport+++GO:2000344///positive regulation of acrosome reaction" 14657 14657 'Glra4' mRNA 63 73 63 0.42 0.48 0.45 0.13 0.25 0.16 0.45 0.18 22 42 26 66.33333333 30 0.003262268 -1.150771168 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098690///glycinergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0016594///glycine binding+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0022824///transmitter-gated ion channel activity+++GO:0030594///neurotransmitter receptor activity "GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043200///response to amino acid+++GO:0050877///nervous system process+++GO:0060012///synaptic transmission, glycinergic+++GO:0060079///excitatory postsynaptic potential+++GO:1902476///chloride transmembrane transport" 14658 14658 'Glrb' mRNA 3357 3619 2618 60.38 64.04 49.89 40.86 46.49 43.74 58.10333333 43.69666667 2616 2903 2713 3198 2744 0.016733434 -0.225233291 04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016935///glycine-gated chloride channel complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0034707///chloride channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098690///glycinergic synapse+++GO:0098982///GABA-ergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0016594///glycine binding+++GO:0016933///extracellularly glycine-gated ion channel activity+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0044877///protein-containing complex binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001964///startle response+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007340///acrosome reaction+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0007628///adult walking behavior+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043200///response to amino acid+++GO:0050877///nervous system process+++GO:0050905///neuromuscular process+++GO:0060012///synaptic transmission, glycinergic+++GO:0060013///righting reflex+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:1902476///chloride transmembrane transport" 14659 14659 'Glrp1' mRNA 2 2 4 0.06 0.06 0.12 0.23 0.18 0.24 0.08 0.216666667 9 7 9 2.666666667 8.333333333 0.170848003 1.618878154 GO:0005634///nucleus GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 14660 14660 'Gls' mRNA 897.48 953.76 813.38 11.76 12.33 11.43 10.98 9.84 9.79 11.84 10.20333333 963.46 847.09 836.92 888.2066667 882.49 0.872494105 -0.019845011 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00470///D-Amino acid metabolism+++04724///Glutamatergic synapse+++04727///GABAergic synapse+++04964///Proximal tubule bicarbonate reclamation+++05206///MicroRNAs in cancer+++05230///Central carbon metabolism in cancer" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0045202///synapse GO:0004359///glutaminase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0001967///suckling behavior+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006537///glutamate biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0006543///glutamine catabolic process+++GO:0007268///chemical synaptic transmission+++GO:0051289///protein homotetramerization+++GO:0090461///glutamate homeostasis 14661 14661 'Glud1' mRNA 1536 1685 1647 26.62 28.74 30.28 42.69 38.73 41.42 28.54666667 40.94666667 2834 2511 2663 1622.666667 2669.333333 1.18E-20 0.704373781 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00910///Nitrogen metabolism+++01200///Carbon metabolism+++04217///Necroptosis+++04964///Proximal tubule bicarbonate reclamation" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum "GO:0000166///nucleotide binding+++GO:0004352///glutamate dehydrogenase (NAD+) activity+++GO:0004353///glutamate dehydrogenase [NAD(P)+] activity+++GO:0004354///glutamate dehydrogenase (NADP+) activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016491///oxidoreductase activity+++GO:0016639///oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor+++GO:0019899///enzyme binding+++GO:0043531///ADP binding+++GO:0070403///NAD+ binding+++GO:0070728///leucine binding" GO:0006520///cellular amino acid metabolic process+++GO:0006537///glutamate biosynthetic process+++GO:0006538///glutamate catabolic process+++GO:0006541///glutamine metabolic process+++GO:0007616///long-term memory+++GO:0010044///response to aluminum ion+++GO:0021549///cerebellum development+++GO:0032024///positive regulation of insulin secretion+++GO:0072350///tricarboxylic acid metabolic process 14663 14663 'Glycam1' mRNA 10 6 9 1.18 0.71 1.13 17 16.46 20.94 1.006666667 18.13333333 164 155 195 8.333333333 171.3333333 2.20E-30 4.349590538 04514///Cell adhesion molecules GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0043199///sulfate binding+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0009617///response to bacterium 14664 14664 'Slc6a9' mRNA 493.32 543.94 395.06 8.41 9.2 7.18 5.61 4.8 4.61 8.263333333 5.006666667 380 311.12 294 477.44 328.3733333 2.19E-04 -0.546993486 04721///Synaptic vesicle cycle GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0032279///asymmetric synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005283///amino acid:sodium symporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015293///symporter activity "GO:0001504///neurotransmitter uptake+++GO:0003333///amino acid transmembrane transport+++GO:0006836///neurotransmitter transport+++GO:0006865///amino acid transport+++GO:0015816///glycine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0055085///transmembrane transport+++GO:0061537///glycine secretion, neurotransmission+++GO:0070455///positive regulation of heme biosynthetic process+++GO:1903804///glycine import across plasma membrane+++GO:1903825///organic acid transmembrane transport+++GO:1904256///positive regulation of iron channel activity+++GO:1904440///positive regulation of ferrous iron import across plasma membrane+++GO:1904782///negative regulation of NMDA glutamate receptor activity" 14667 14667 'Gm2a' mRNA 9765 10262 9880 123.44 127.58 132.47 116.25 119.41 117.46 127.83 117.7066667 10586 10623 10360 9969 10523 0.303602899 0.065928086 04142///Lysosome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0005319///lipid transporter activity+++GO:0008047///enzyme activator activity+++GO:0016004///phospholipase activator activity+++GO:0016787///hydrolase activity+++GO:0032428///beta-N-acetylgalactosaminidase activity GO:0001573///ganglioside metabolic process+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0006869///lipid transport+++GO:0007611///learning or memory+++GO:0009313///oligosaccharide catabolic process+++GO:0019915///lipid storage+++GO:0050877///nervous system process+++GO:0050885///neuromuscular process controlling balance+++GO:0051345///positive regulation of hydrolase activity 14670 14670 'Gnl1' mRNA 1434 1401.98 1226.98 28.75 27.62 26.15 24.02 24.14 21.95 27.50666667 23.37 1374 1352 1219 1354.32 1315 0.642162509 -0.051398072 GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006974///cellular response to DNA damage stimulus 14672 14672 'Gna11' mRNA 2022 1899 2006 32.54 30.07 34.25 32.29 28.78 30.17 32.28666667 30.41333333 2309 2010 2089 1975.666667 2136 0.287178449 0.098024446 "04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04540///Gap junction+++04725///Cholinergic synapse+++04730///Long-term depression+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05142///Chagas disease+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity GO:0001501///skeletal system development+++GO:0001508///action potential+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007507///heart development+++GO:0008217///regulation of blood pressure+++GO:0010259///multicellular organism aging+++GO:0045634///regulation of melanocyte differentiation+++GO:0048066///developmental pigmentation+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0071467///cellular response to pH+++GO:0086100///endothelin receptor signaling pathway+++GO:1904888///cranial skeletal system development 14673 14673 'Gna12' mRNA 189 198 176 5.76 5.95 5.69 7.53 7.04 8.17 5.8 7.58 284 259 298 187.6666667 280.3333333 6.74E-04 0.568263712 "04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04928///Parathyroid hormone synthesis, secretion and action+++05130///Pathogenic Escherichia coli infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer" GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0031526///brush border membrane GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031752///D5 dopamine receptor binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0008217///regulation of blood pressure+++GO:0008360///regulation of cell shape+++GO:0010259///multicellular organism aging+++GO:0010762///regulation of fibroblast migration+++GO:0030154///cell differentiation+++GO:0032006///regulation of TOR signaling+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0042733///embryonic digit morphogenesis+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration 14674 14674 'Gna13' mRNA 1475 1465 1356 19.57 19.51 17.68 21.14 19.96 20.61 18.92 20.57 1974 1842 1933 1432 1916.333333 1.10E-08 0.409177508 "04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04611///Platelet activation+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04928///Parathyroid hormone synthesis, secretion and action+++05130///Pathogenic Escherichia coli infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0042470///melanosome GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031752///D5 dopamine receptor binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007266///Rho protein signal transduction+++GO:0008217///regulation of blood pressure+++GO:0008360///regulation of cell shape+++GO:0010259///multicellular organism aging+++GO:0030154///cell differentiation+++GO:0030168///platelet activation+++GO:0030334///regulation of cell migration+++GO:0031584///activation of phospholipase D activity+++GO:0035556///intracellular signal transduction+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration 14675 14675 'Gna14' mRNA 1086 1170 1098 17 18.07 18.33 11.55 12.04 11.91 17.8 11.83333333 846 855 847 1118 849.3333333 5.98E-06 -0.407989266 04020///Calcium signaling pathway+++05142///Chagas disease+++05146///Amoebiasis GO:0005834///heterotrimeric G-protein complex GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0046872///metal ion binding GO:0001508///action potential+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway 14676 14676 'Gna15' mRNA 49 32 36 1.35 0.92 1.08 8.39 10.12 8.19 1.116666667 8.9 345 404 329 39 359.3333333 1.81E-47 3.194206218 04020///Calcium signaling pathway+++04926///Relaxin signaling pathway+++05142///Chagas disease+++05146///Amoebiasis GO:0005834///heterotrimeric G-protein complex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0046872///metal ion binding GO:0001508///action potential+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway 14677 14677 'Gnai1' mRNA 1193 1259 418 20.44 21.22 7.6 7.4 8.46 10.27 16.42 8.71 497 555 668 956.6666667 573.3333333 0.175218808 -0.726315625 "04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04360///Axon guidance+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04971///Gastric acid secretion+++05012///Parkinson disease+++05030///Cocaine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05133///Pertussis+++05142///Chagas disease+++05145///Toxoplasmosis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation" GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005834///heterotrimeric G-protein complex+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0099738///cell cortex region GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0019003///GDP binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0032794///GTPase activating protein binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0050805///negative regulation of synaptic transmission+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:1904322///cellular response to forskolin+++GO:1904778///positive regulation of protein localization to cell cortex 14678 14678 'Gnai2' mRNA 1531 1383 1191 39.81 35.61 32.98 63.37 61.11 64.41 36.13333333 62.96333333 2802 2638 2762 1368.333333 2734 1.65E-37 0.989826089 "04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04360///Axon guidance+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04971///Gastric acid secretion+++05012///Parkinson disease+++05030///Cocaine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05133///Pertussis+++05142///Chagas disease+++05145///Toxoplasmosis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0001973///adenosine receptor signaling pathway+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0008016///regulation of heart contraction+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0035810///positive regulation of urine volume+++GO:0035815///positive regulation of renal sodium excretion+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0050805///negative regulation of synaptic transmission+++GO:0051301///cell division+++GO:0051924///regulation of calcium ion transport+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0140199///negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:1903614///negative regulation of protein tyrosine phosphatase activity+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2001234///negative regulation of apoptotic signaling pathway 14679 14679 'Gnai3' mRNA 2513 2549 2370 41.93 41.85 41.95 40.6 40.93 42.61 41.91 41.38 2800 2757 2846 2477.333333 2801 0.01229974 0.166226218 "04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04360///Axon guidance+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04971///Gastric acid secretion+++05012///Parkinson disease+++05030///Cocaine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05133///Pertussis+++05142///Chagas disease+++05145///Toxoplasmosis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation" GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005834///heterotrimeric G-protein complex+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0042588///zymogen granule+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0032794///GTPase activating protein binding+++GO:0046872///metal ion binding GO:0006906///vesicle fusion+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007420///brain development+++GO:0008016///regulation of heart contraction+++GO:0016239///positive regulation of macroautophagy+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0046039///GTP metabolic process+++GO:0051301///cell division+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2001234///negative regulation of apoptotic signaling pathway 14680 14680 'Gnal' mRNA 51.14 59.95 39.92 0.49 0.58 0.42 0.52 0.56 0.45 0.496666667 0.51 60.65 64.8 51.75 50.33666667 59.06666667 0.597214093 0.226895056 04020///Calcium signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++05012///Parkinson disease+++05142///Chagas disease+++05146///Amoebiasis GO:0005834///heterotrimeric G-protein complex GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0001975///response to amphetamine+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007606///sensory perception of chemical stimulus+++GO:0007608///sensory perception of smell+++GO:0031000///response to caffeine 14681 14681 'Gnao1' mRNA 504 442 337 6.73 6.02 4.54 2.67 2.75 3.52 5.763333333 2.98 275 251 329 427.6666667 285 3.93E-04 -0.591158247 04015///Rap1 signaling pathway+++04361///Axon regeneration+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05142///Chagas disease+++05145///Toxoplasmosis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0031852///mu-type opioid receptor binding+++GO:0032794///GTPase activating protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051430///corticotropin-releasing hormone receptor 1 binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007568///aging+++GO:0007626///locomotory behavior+++GO:0008016///regulation of heart contraction+++GO:0009987///cellular process+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0034097///response to cytokine+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043278///response to morphine+++GO:0043547///positive regulation of GTPase activity+++GO:0051926///negative regulation of calcium ion transport 14682 14682 'Gnaq' mRNA 1242 1276 1064 9.58 9.68 8.71 9.34 8.54 10.52 9.323333333 9.466666667 1394 1246 1521 1194 1387 0.036676376 0.207023724 "04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05135///Yersinia infection+++05142///Chagas disease+++05143///African trypanosomiasis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer" GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0044297///cell body+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity GO:0001501///skeletal system development+++GO:0001508///action potential+++GO:0006469///negative regulation of protein kinase activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007215///glutamate receptor signaling pathway+++GO:0007507///heart development+++GO:0008217///regulation of blood pressure+++GO:0009791///post-embryonic development+++GO:0010259///multicellular organism aging+++GO:0016322///neuron remodeling+++GO:0021884///forebrain neuron development+++GO:0042711///maternal behavior+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043267///negative regulation of potassium ion transport+++GO:0045634///regulation of melanocyte differentiation+++GO:0048066///developmental pigmentation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050821///protein stabilization+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0086100///endothelin receptor signaling pathway+++GO:1904888///cranial skeletal system development 14683 14683 'Gnas' mRNA 12024 12129 4919 398.92 397.51 184.8 176.55 187.47 207.27 327.0766667 190.43 5756 6057 6644 9690.666667 6152.333333 0.133321899 -0.646986474 "01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05110///Vibrio cholerae infection+++05142///Chagas disease+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0001726///ruffle+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030133///transport vesicle+++GO:0030142///COPI-coated Golgi to ER transport vesicle+++GO:0030425///dendrite+++GO:0031224///intrinsic component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0003924///GTPase activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0010856///adenylate cyclase activator activity+++GO:0019001///guanyl nucleotide binding+++GO:0019904///protein domain specific binding+++GO:0031681///G-protein beta-subunit binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0031748///D1 dopamine receptor binding+++GO:0031852///mu-type opioid receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity+++GO:0051430///corticotropin-releasing hormone receptor 1 binding GO:0001501///skeletal system development+++GO:0001894///tissue homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001958///endochondral ossification+++GO:0006112///energy reserve metabolic process+++GO:0006306///DNA methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007606///sensory perception of chemical stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009791///post-embryonic development+++GO:0009966///regulation of signal transduction+++GO:0010765///positive regulation of sodium ion transport+++GO:0031279///regulation of cyclase activity+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0035814///negative regulation of renal sodium excretion+++GO:0040015///negative regulation of multicellular organism growth+++GO:0040032///post-embryonic body morphogenesis+++GO:0042493///response to drug+++GO:0043547///positive regulation of GTPase activity+++GO:0043588///skin development+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045776///negative regulation of blood pressure+++GO:0048589///developmental growth+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0050890///cognition+++GO:0051216///cartilage development+++GO:0055074///calcium ion homeostasis+++GO:0060348///bone development+++GO:0060789///hair follicle placode formation+++GO:0070527///platelet aggregation+++GO:0071107///response to parathyroid hormone+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071514///genetic imprinting+++GO:0071870///cellular response to catecholamine stimulus+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2000828///regulation of parathyroid hormone secretion 14685 14685 'Gnat1' mRNA 1 4 1 0.02 0.1 0.03 0.11 0.02 0.07 0.05 0.066666667 5 1 3 2 3 0.78666572 0.58030104 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding "GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0001973///adenosine receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0007603///phototransduction, visible light+++GO:0008283///cell proliferation+++GO:0009642///response to light intensity+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0042462///eye photoreceptor cell development+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0050917///sensory perception of umami taste+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0060041///retina development in camera-type eye+++GO:0071257///cellular response to electrical stimulus" 14686 14686 'Gnat2' mRNA 18 19 18 0.56 0.61 0.62 0.42 0.42 0.28 0.596666667 0.373333333 15 15 10 18.33333333 13.33333333 0.527522352 -0.471638012 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009642///response to light intensity+++GO:0046549///retinal cone cell development+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception 14687 14687 'Gnaz' mRNA 274 266 163 4.23 4.12 2.74 0.86 1.31 0.98 3.696666667 1.05 61 95 70 234.3333333 75.33333333 3.73E-11 -1.635723889 04730///Long-term depression GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0098664///G protein-coupled serotonin receptor signaling pathway 14688 14688 'Gnb1' mRNA 4866 4600 4955 86.13 80.02 93.09 92.84 89.83 90.81 86.41333333 91.16 6043 5710 5724 4807 5825.666667 1.38E-04 0.262759286 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04744///Phototransduction+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0042622///photoreceptor outer segment membrane+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0003924///GTPase activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030507///spectrin binding+++GO:0031682///G-protein gamma-subunit binding+++GO:0044877///protein-containing complex binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity+++GO:0051020///GTPase binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007603///phototransduction, visible light+++GO:0008283///cell proliferation+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0050909///sensory perception of taste+++GO:0060041///retina development in camera-type eye+++GO:0071456///cellular response to hypoxia" 14693 14693 'Gnb2' mRNA 2671.63 2699.3 922.07 92.82 92.86 33.97 46.91 64.66 60.54 73.21666667 57.37 1538.01 2069 1933 2097.666667 1846.67 0.800369356 -0.170064889 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031682///G-protein gamma-subunit binding+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 14694 14694 'Rack1' mRNA 1950 2000 1884 94.7 95.9 97.08 181 166.05 181.09 95.89333333 176.0466667 4278 3828 4139 1944.666667 4081.666667 6.15E-64 1.057473984 05162///Measles GO:0001891///phagocytic cup+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:1990630///IRE1-RACK1-PP2A complex GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008200///ion channel inhibitor activity+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0030332///cyclin binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0035591///signaling adaptor activity+++GO:0038023///signaling receptor activity+++GO:0042169///SH2 domain binding+++GO:0042803///protein homodimerization activity+++GO:0043022///ribosome binding+++GO:0051434///BH3 domain binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0008104///protein localization+++GO:0010629///negative regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0017148///negative regulation of translation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0031334///positive regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032880///regulation of protein localization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:0043065///positive regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0043547///positive regulation of GTPase activity+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048511///rhythmic process+++GO:0050765///negative regulation of phagocytosis+++GO:0051302///regulation of cell division+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051726///regulation of cell cycle+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0071333///cellular response to glucose stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0072344///rescue of stalled ribosome+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:2000114///regulation of establishment of cell polarity+++GO:2000543///positive regulation of gastrulation+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 14695 14695 'Gnb3' mRNA 8 5 11 0.25 0.15 0.36 0.68 0.39 0.34 0.253333333 0.47 25 14 12 8 17 0.191415873 1.058138826 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04742///Taste transduction+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0044297///cell body GO:0003924///GTPase activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030507///spectrin binding+++GO:0031682///G-protein gamma-subunit binding+++GO:0051020///GTPase binding GO:0006884///cell volume homeostasis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010906///regulation of glucose metabolic process+++GO:0032350///regulation of hormone metabolic process+++GO:0045598///regulation of fat cell differentiation+++GO:0090181///regulation of cholesterol metabolic process+++GO:0090207///regulation of triglyceride metabolic process+++GO:1903725///regulation of phospholipid metabolic process 14696 14696 'Gnb4' mRNA 525.74 531.36 543.86 4.01 4.01 4.4 5.42 5.85 5.25 4.14 5.506666667 790.4 811.18 727.48 533.6533333 776.3533333 1.46E-06 0.529167485 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005834///heterotrimeric G-protein complex+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0003924///GTPase activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031682///G-protein gamma-subunit binding+++GO:0044877///protein-containing complex binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 14697 14697 'Gnb5' mRNA 1373 1557 1529 34.75 38.81 41.05 21.11 19.63 19.27 38.20333333 20.00333333 959 871 848 1486.333333 892.6666667 7.99E-16 -0.749681232 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0044297///cell body+++GO:0098793///presynapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031682///G-protein gamma-subunit binding+++GO:0032794///GTPase activating protein binding+++GO:0051087///chaperone binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0036367///light adaption+++GO:0043547///positive regulation of GTPase activity+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1990603///dark adaptation 14699 14699 'Gngt1' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04744///Phototransduction+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0003924///GTPase activity+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007602///phototransduction+++GO:0008104///protein localization+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0042462///eye photoreceptor cell development+++GO:0071456///cellular response to hypoxia 14700 14700 'Gng10' mRNA 1022 1072 995 56.84 58.91 58.72 81.84 80.85 91.57 58.15666667 84.75333333 1688 1626 1826 1029.666667 1713.333333 7.76E-19 0.72348984 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 14701 14701 'Gng12' mRNA 1320 1281 1295 16.81 16.07 17.5 23.98 26.22 24.12 16.79333333 24.77333333 2168 2320 2107 1298.666667 2198.333333 4.55E-21 0.747541187 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04810///Regulation of actin cytoskeleton+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0030165///PDZ domain binding+++GO:0031681///G-protein beta-subunit binding+++GO:0042301///phosphate ion binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0021987///cerebral cortex development+++GO:0032496///response to lipopolysaccharide 14702 14702 'Gng2' mRNA 994 1014 1004 14.62 14.67 15.7 21.21 19.88 20.12 14.99666667 20.40333333 1667 1518 1529 1004 1571.333333 7.88E-15 0.633115565 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0003924///GTPase activity+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008283///cell proliferation 14704 14704 'Gng3' mRNA 60.73 58.27 47.49 2.08 1.96 1.72 0.8 0.9 0.65 1.92 0.783333333 26.81 29.5 21.28 55.49666667 25.86333333 0.0053738 -1.125776966 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031680///G-protein beta/gamma-subunit complex+++GO:0044297///cell body GO:0003924///GTPase activity+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration 14705 14705 'Bscl2' mRNA 1788.27 1921.73 1770.51 60.9 63.48 64.33 86.66 85.21 84.42 62.90333333 85.43 2645.19 2553.5 2499.72 1826.836667 2566.136667 1.23E-12 0.478900128 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0005543///phospholipid binding GO:0006629///lipid metabolic process+++GO:0014853///regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction+++GO:0016042///lipid catabolic process+++GO:0019915///lipid storage+++GO:0034389///lipid droplet organization+++GO:0043086///negative regulation of catalytic activity+++GO:0045444///fat cell differentiation+++GO:0048515///spermatid differentiation+++GO:0050995///negative regulation of lipid catabolic process+++GO:0060612///adipose tissue development+++GO:0061725///cytosolic lipolysis+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0140042///lipid droplet formation+++GO:1905693///regulation of phosphatidic acid biosynthetic process 14706 14706 'Gng4' mRNA 69 55 74 1.21 0.99 1.43 0.03 0.09 0.07 1.21 0.063333333 2 6 4 66 4 2.19E-12 -4.059192466 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0003924///GTPase activity+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030308///negative regulation of cell growth 14707 14707 'Gng5' mRNA 2257 2277.6 2200.6 342.96 345.54 355.01 457.67 491.72 495.49 347.8366667 481.6266667 3429.3 3577 3573.98 2245.066667 3526.76 1.27E-22 0.64043412 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005739///mitochondrion+++GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0030165///PDZ domain binding+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0072513///positive regulation of secondary heart field cardioblast proliferation+++GO:2000179///positive regulation of neural precursor cell proliferation 14708 14708 'Gng7' mRNA 1659 1885 1629 26.85 30.05 27.98 15.37 15.06 14.31 28.29333333 14.91333333 1093 1044 985 1724.333333 1040.666667 1.82E-19 -0.739172295 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0031681///G-protein beta-subunit binding GO:0001662///behavioral fear response+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007626///locomotory behavior+++GO:0045761///regulation of adenylate cyclase activity 14709 14709 'Gng8' mRNA 5 14 15 0.29 0.86 0.88 0.68 0.89 1.1 0.676666667 0.89 13 17 20 11.33333333 16.66666667 0.524041871 0.539373571 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007399///nervous system development+++GO:0035176///social behavior+++GO:0043584///nose development+++GO:0071444///cellular response to pheromone 14710 14710 'Gngt2' mRNA 36 45 45 5.07 6.31 6.71 63.12 77.04 65.61 6.03 68.59 514 611 517 42 547.3333333 3.01E-80 3.693336835 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0003924///GTPase activity+++GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 14711 14711 'Gnmt' mRNA 230 293 259 14.14 17.81 16.9 4.93 3.85 4.77 16.28333333 4.516666667 92 70 86 260.6666667 82.66666667 2.32E-16 -1.669974679 "00260///Glycine, serine and threonine metabolism" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034708///methyltransferase complex GO:0005542///folic acid binding+++GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016594///glycine binding+++GO:0016740///transferase activity+++GO:0017174///glycine N-methyltransferase activity+++GO:0042802///identical protein binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0005977///glycogen metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0006544///glycine metabolic process+++GO:0006555///methionine metabolic process+++GO:0006730///one-carbon metabolic process+++GO:0032259///methylation+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0051289///protein homotetramerization+++GO:1901052///sarcosine metabolic process 14712 14712 'Gnpat' mRNA 1850 1959 1873 34.07 35.5 36.59 26.97 29.97 29.27 35.38666667 28.73666667 1685 1829 1771 1894 1761.666667 0.192096077 -0.115627702 00564///Glycerophospholipid metabolism+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane "GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008374///O-acyltransferase activity+++GO:0016287///glycerone-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006631///fatty acid metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0007416///synapse assembly+++GO:0007584///response to nutrient+++GO:0008611///ether lipid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0021587///cerebellum morphogenesis+++GO:0030913///paranodal junction assembly+++GO:0042493///response to drug+++GO:0042552///myelination+++GO:0042594///response to starvation+++GO:0044255///cellular lipid metabolic process+++GO:0061024///membrane organization+++GO:0070542///response to fatty acid 14714 14714 'Gnrh1' mRNA 1 2 1 0.14 0.27 0.15 0.36 0.12 0.38 0.186666667 0.286666667 3 1 3 1.333333333 2.333333333 0.738188976 0.797869553 04080///Neuroactive ligand-receptor interaction+++04912///GnRH signaling pathway+++04929///GnRH secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005798///Golgi-associated vesicle+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:1990008///neurosecretory vesicle GO:0005179///hormone activity+++GO:0005183///gonadotropin hormone-releasing hormone activity+++GO:0031530///gonadotropin-releasing hormone receptor binding GO:0000003///reproduction+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0010468///regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0030238///male sex determination+++GO:0031960///response to corticosteroid+++GO:0032496///response to lipopolysaccharide+++GO:0033087///negative regulation of immature T cell proliferation+++GO:0033574///response to testosterone+++GO:0034695///response to prostaglandin E+++GO:0035864///response to potassium ion+++GO:0042698///ovulation cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0044849///estrous cycle+++GO:0045471///response to ethanol+++GO:0048545///response to steroid hormone+++GO:1990637///response to prolactin+++GO:2000354///regulation of ovarian follicle development+++GO:2001223///negative regulation of neuron migration 14715 14715 'Gnrhr' mRNA 3 4 0 0.1 0.09 0 0.02 0.06 0.03 0.063333333 0.036666667 1 3 1 2.333333333 1.666666667 0.863090843 -0.456630332 04080///Neuroactive ligand-receptor interaction+++04912///GnRH signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004968///gonadotropin-releasing hormone receptor activity+++GO:0016500///protein-hormone receptor activity+++GO:0016520///growth hormone-releasing hormone receptor activity+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0097211///cellular response to gonadotropin-releasing hormone 14718 14718 'Got1' mRNA 1667 1588 1583 45.98 43.14 46.32 52.75 58.23 49.69 45.14666667 53.55666667 2199 2370 2005 1612.666667 2191.333333 3.68E-07 0.430864062 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids" GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0043679///axon terminus GO:0003824///catalytic activity+++GO:0004069///L-aspartate:2-oxoglutarate aminotransferase activity+++GO:0004609///phosphatidylserine decarboxylase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0031406///carboxylic acid binding+++GO:0047801///L-cysteine:2-oxoglutarate aminotransferase activity GO:0006103///2-oxoglutarate metabolic process+++GO:0006107///oxaloacetate metabolic process+++GO:0006114///glycerol biosynthetic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006531///aspartate metabolic process+++GO:0006532///aspartate biosynthetic process+++GO:0006533///aspartate catabolic process+++GO:0006536///glutamate metabolic process+++GO:0007219///Notch signaling pathway+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0009743///response to carbohydrate+++GO:0019550///glutamate catabolic process to aspartate+++GO:0019551///glutamate catabolic process to 2-oxoglutarate+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0032869///cellular response to insulin stimulus+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0035902///response to immobilization stress+++GO:0043648///dicarboxylic acid metabolic process+++GO:0046686///response to cadmium ion+++GO:0051384///response to glucocorticoid+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051902///negative regulation of mitochondrial depolarization+++GO:0055089///fatty acid homeostasis+++GO:0060290///transdifferentiation+++GO:0071260///cellular response to mechanical stimulus+++GO:1990267///response to transition metal nanoparticle 14719 14719 'Got2' mRNA 4488 4873 4710 105.28 112.55 117.2 94.21 82.97 87.77 111.6766667 88.31666667 4619 3972 4166 4690.333333 4252.333333 0.034657907 -0.155395443 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids+++04975///Fat digestion and absorption" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0043204///perikaryon+++GO:0043209///myelin sheath GO:0003824///catalytic activity+++GO:0004069///L-aspartate:2-oxoglutarate aminotransferase activity+++GO:0005543///phospholipid binding+++GO:0008483///transaminase activity+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0030170///pyridoxal phosphate binding+++GO:0031406///carboxylic acid binding+++GO:0042802///identical protein binding GO:0006103///2-oxoglutarate metabolic process+++GO:0006107///oxaloacetate metabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006531///aspartate metabolic process+++GO:0006532///aspartate biosynthetic process+++GO:0006533///aspartate catabolic process+++GO:0006536///glutamate metabolic process+++GO:0006869///lipid transport+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0009058///biosynthetic process+++GO:0014850///response to muscle activity+++GO:0015908///fatty acid transport+++GO:0019550///glutamate catabolic process to aspartate+++GO:0019551///glutamate catabolic process to 2-oxoglutarate+++GO:0032868///response to insulin+++GO:0043278///response to morphine+++GO:0043648///dicarboxylic acid metabolic process+++GO:0045471///response to ethanol+++GO:0097052///L-kynurenine metabolic process 14723 14723 'Gp1ba' mRNA 17 16 11 0.2 0.21 0.14 0.12 0.15 0.11 0.183333333 0.126666667 12 13 11 14.66666667 12 0.743620693 -0.293910359 04512///ECM-receptor interaction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0031362///anchored component of external side of plasma membrane GO:0000902///cell morphogenesis+++GO:0007155///cell adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0042730///fibrinolysis+++GO:0070527///platelet aggregation 14724 14724 'Gp1bb' mRNA 10.46 3.83 1.64 0.33 0.1 0.05 0.23 0.23 0.13 0.16 0.196666667 8.51 8.43 5.31 5.31 7.416666667 0.677329512 0.591349476 04512///ECM-receptor interaction+++04611///Platelet activation+++04640///Hematopoietic cell lineage GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis 14725 14725 'Lrp2' mRNA 4531 4253 4174 15.27 14.08 14.92 12.99 11.28 12.83 14.75666667 12.36666667 4440 3768 4252 4319.333333 4153.333333 0.393739354 -0.069467395 04340///Hedgehog signaling pathway+++04918///Thyroid hormone synthesis+++04979///Cholesterol metabolism GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031526///brush border membrane+++GO:0031904///endosome lumen+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0044295///axonal growth cone+++GO:0045121///membrane raft+++GO:0045177///apical part of cell GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0017124///SH3 domain binding+++GO:0030165///PDZ domain binding+++GO:0030492///hemoglobin binding+++GO:0031994///insulin-like growth factor I binding+++GO:0035258///steroid hormone receptor binding+++GO:0038023///signaling receptor activity+++GO:0042562///hormone binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0051087///chaperone binding GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0003139///secondary heart field specification+++GO:0003148///outflow tract septum morphogenesis+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003281///ventricular septum development+++GO:0006766///vitamin metabolic process+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0010165///response to X-ray+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0020028///endocytic hemoglobin import+++GO:0030001///metal ion transport+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0035904///aorta development+++GO:0043066///negative regulation of apoptotic process+++GO:0044321///response to leptin+++GO:0045056///transcytosis+++GO:0045807///positive regulation of endocytosis+++GO:0046879///hormone secretion+++GO:0050769///positive regulation of neurogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060068///vagina development+++GO:0060976///coronary vasculature development+++GO:0060982///coronary artery morphogenesis+++GO:0061156///pulmonary artery morphogenesis+++GO:0061642///chemoattraction of axon+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0071363///cellular response to growth factor stimulus+++GO:0097242///amyloid-beta clearance+++GO:0140058///neuron projection arborization+++GO:0140077///positive regulation of lipoprotein transport+++GO:1904447///folate import across plasma membrane 14726 14726 'Pdpn' mRNA 1387 1406 1443 43.36 43.33 47.87 122.17 122.9 124.27 44.85333333 123.1133333 4491 4410 4420 1412 4440.333333 1.12E-131 1.639827956 GO:0001726///ruffle+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031258///lamellipodium membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031527///filopodium membrane+++GO:0031528///microvillus membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0061851///leading edge of lamellipodium+++GO:0097197///tetraspanin-enriched microdomain GO:0005102///signaling receptor binding+++GO:0005372///water transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0019956///chemokine binding+++GO:0051087///chaperone binding "GO:0000902///cell morphogenesis+++GO:0001946///lymphangiogenesis+++GO:0003333///amino acid transmembrane transport+++GO:0006693///prostaglandin metabolic process+++GO:0006833///water transport+++GO:0006865///amino acid transport+++GO:0006928///movement of cell or subcellular component+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010572///positive regulation of platelet activation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0015884///folic acid transport+++GO:0030155///regulation of cell adhesion+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0035239///tube morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0044319///wound healing, spreading of cells+++GO:0048286///lung alveolus development+++GO:0048535///lymph node development+++GO:0051272///positive regulation of cellular component movement+++GO:0055093///response to hyperoxia+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0061032///visceral serous pericardium development+++GO:0070252///actin-mediated cell contraction+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0098609///cell-cell adhesion+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1901731///positive regulation of platelet aggregation+++GO:1904328///regulation of myofibroblast contraction+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:2000392///regulation of lamellipodium morphogenesis" 14727 14727 'Lilr4b' mRNA 35.55 15.15 15.29 1.41 0.6 0.72 42.79 40.43 40.96 0.91 41.39333333 1193.59 1108.53 1111.16 21.99666667 1137.76 5.78E-162 5.703835701 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019903///protein phosphatase binding+++GO:0030293///transmembrane receptor protein tyrosine kinase inhibitor activity+++GO:0030547///receptor inhibitor activity "GO:0002507///tolerance induction+++GO:0002669///positive regulation of T cell anergy+++GO:0002725///negative regulation of T cell cytokine production+++GO:0002774///Fc receptor mediated inhibitory signaling pathway+++GO:0031623///receptor internalization+++GO:0032682///negative regulation of chemokine production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0043409///negative regulation of MAPK cascade+++GO:0045584///negative regulation of cytotoxic T cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0071659///negative regulation of IP-10 production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000524///negative regulation of T cell costimulation" 14728 14728 'Lilrb4a' mRNA 89.45 103.85 126.71 3.9 4.04 5.39 149.68 147.54 143.85 4.443333333 147.0233333 4125.41 3887.47 3828.84 106.67 3947.24 0 5.204742215 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding+++GO:0019903///protein phosphatase binding+++GO:0030293///transmembrane receptor protein tyrosine kinase inhibitor activity+++GO:0030547///receptor inhibitor activity "GO:0001780///neutrophil homeostasis+++GO:0001816///cytokine production+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0002507///tolerance induction+++GO:0002669///positive regulation of T cell anergy+++GO:0002725///negative regulation of T cell cytokine production+++GO:0002774///Fc receptor mediated inhibitory signaling pathway+++GO:0006954///inflammatory response+++GO:0007596///blood coagulation+++GO:0009611///response to wounding+++GO:0009624///response to nematode+++GO:0009991///response to extracellular stimulus+++GO:0031623///receptor internalization+++GO:0032496///response to lipopolysaccharide+++GO:0032602///chemokine production+++GO:0032682///negative regulation of chemokine production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033007///negative regulation of mast cell activation involved in immune response+++GO:0035739///CD4-positive, alpha-beta T cell proliferation+++GO:0035740///CD8-positive, alpha-beta T cell proliferation+++GO:0042092///type 2 immune response+++GO:0042130///negative regulation of T cell proliferation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0043409///negative regulation of MAPK cascade+++GO:0045584///negative regulation of cytotoxic T cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051707///response to other organism+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071659///negative regulation of IP-10 production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000524///negative regulation of T cell costimulation" 14729 14729 'Gp5' mRNA 11 4 2 0.28 0.1 0.05 0.18 0.11 0.02 0.143333333 0.103333333 8 5 1 5.666666667 4.666666667 0.863090843 -0.282205627 04512///ECM-receptor interaction+++04611///Platelet activation+++04640///Hematopoietic cell lineage GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005518///collagen binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010544///negative regulation of platelet activation 14731 14731 'Gpaa1' mRNA 1784 1788 1712 49.79 49.16 50.69 45.59 45.08 43.54 49.88 44.73666667 1878 1813 1736 1761.333333 1809 0.791796996 0.026678081 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042765///GPI-anchor transamidase complex GO:0003923///GPI-anchor transamidase activity+++GO:0034235///GPI anchor binding GO:0006506///GPI anchor biosynthetic process+++GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0065003///protein-containing complex assembly 14732 14732 'Gpam' mRNA 1600 1662 1494 14.18 14.52 14.07 6.39 6.47 6.88 14.25666667 6.58 830 821 866 1585.333333 839 3.85E-31 -0.928359645 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0004366///glycerol-3-phosphate O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0102420///sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity" GO:0001817///regulation of cytokine production+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009749///response to glucose+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0014823///response to activity+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0032623///interleukin-2 production+++GO:0032869///cellular response to insulin stimulus+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0044255///cellular lipid metabolic process+++GO:0051607///defense response to virus+++GO:0055089///fatty acid homeostasis+++GO:0055091///phospholipid homeostasis+++GO:0070236///negative regulation of activation-induced cell death of T cells 14733 14733 'Gpc1' mRNA 1252.81 1222.32 809.69 18.82 18.03 12.91 8.99 6.92 8.78 16.58666667 8.23 689.52 520.99 650.62 1094.94 620.3766667 1.63E-09 -0.82551924 05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005796///Golgi lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005507///copper ion binding+++GO:0017134///fibroblast growth factor binding+++GO:0043236///laminin binding+++GO:0070052///collagen V binding GO:0009966///regulation of signal transduction+++GO:0014037///Schwann cell differentiation+++GO:0016477///cell migration+++GO:0030200///heparan sulfate proteoglycan catabolic process+++GO:0032288///myelin assembly+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:1905475///regulation of protein localization to membrane+++GO:2001016///positive regulation of skeletal muscle cell differentiation 14734 14734 'Gpc3' mRNA 1221 1246 1132 30.25 30.39 29.75 8.7 8.18 8.3 30.13 8.393333333 404 371 373 1199.666667 382.6666667 3.11E-68 -1.65957414 05205///Proteoglycans in cancer GO:0005764///lysosome+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity+++GO:0060422///peptidyl-dipeptidase inhibitor activity "GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0008285///negative regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0009887///animal organ morphogenesis+++GO:0009948///anterior/posterior axis specification+++GO:0009966///regulation of signal transduction+++GO:0010171///body morphogenesis+++GO:0010466///negative regulation of peptidase activity+++GO:0016477///cell migration+++GO:0030282///bone mineralization+++GO:0030316///osteoclast differentiation+++GO:0030324///lung development+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0040008///regulation of growth+++GO:0042074///cell migration involved in gastrulation+++GO:0043086///negative regulation of catalytic activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0045807///positive regulation of endocytosis+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045926///negative regulation of growth+++GO:0046326///positive regulation of glucose import+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0052547///regulation of peptidase activity+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0060976///coronary vasculature development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072138///mesenchymal cell proliferation involved in ureteric bud development+++GO:0072180///mesonephric duct morphogenesis+++GO:0072203///cell proliferation involved in metanephros development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1905475///regulation of protein localization to membrane+++GO:2000050///regulation of non-canonical Wnt signaling pathway+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway" 14735 14735 'Gpc4' mRNA 1260.8 1314 1250 23.29 23.86 24.86 29.53 29.15 31.58 24.00333333 30.08666667 1770 1695 1849 1274.933333 1771.333333 2.62E-09 0.462944441 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0098978///glutamatergic synapse+++GO:0099026///anchored component of presynaptic membrane GO:0009966///regulation of signal transduction+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0099560///synaptic membrane adhesion+++GO:1905475///regulation of protein localization to membrane+++GO:1905606///regulation of presynapse assembly 14739 14739 'S1pr2' mRNA 1135 1139 1042 21.73 21.54 21.43 27.87 28.63 26.03 21.56666667 27.51 1652 1662 1502 1105.333333 1605.333333 7.08E-11 0.527838923 04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001664///G protein-coupled receptor binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0038036///sphingosine-1-phosphate receptor activity GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0019222///regulation of metabolic process+++GO:0031532///actin cytoskeleton reorganization+++GO:0046847///filopodium assembly+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation 14744 14744 'Gpr65' mRNA 46 76 56 1.21 1.97 1.56 12.25 12.66 11.19 1.58 12.03333333 535 540 473 59.33333333 516 1.33E-63 3.110706943 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010447///response to acidic pH+++GO:0031532///actin cytoskeleton reorganization+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0090630///activation of GTPase activity 14745 14745 'Lpar1' mRNA 3075 3186 3068 49.52 50.75 52.58 53.72 49.05 52.29 50.95 51.68666667 3824 3420 3616 3109.666667 3620 0.001756899 0.20634187 04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04540///Gap junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0030165///PDZ domain binding+++GO:0035727///lysophosphatidic acid binding+++GO:0070915///lysophosphatidic acid receptor activity GO:0000187///activation of MAPK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007420///brain development+++GO:0008360///regulation of cell shape+++GO:0010942///positive regulation of cell death+++GO:0010977///negative regulation of neuron projection development+++GO:0014003///oligodendrocyte development+++GO:0019222///regulation of metabolic process+++GO:0021549///cerebellum development+++GO:0021554///optic nerve development+++GO:0022008///neurogenesis+++GO:0022038///corpus callosum development+++GO:0032060///bleb assembly+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0042552///myelination+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060326///cell chemotaxis+++GO:0060999///positive regulation of dendritic spine development+++GO:0071453///cellular response to oxygen levels+++GO:0071673///positive regulation of smooth muscle cell chemotaxis+++GO:1904566///cellular response to 1-oleoyl-sn-glycerol 3-phosphate 14747 14747 'Cmklr1' mRNA 32 26 22 0.6 0.48 0.44 8.52 8.07 9.55 0.506666667 8.713333333 517 479 563 26.66666667 519.6666667 1.28E-86 4.274720538 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004875///complement receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0097003///adipokinetic hormone receptor activity+++GO:0097004///adipokinetic hormone binding GO:0002430///complement receptor mediated signaling pathway+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032695///negative regulation of interleukin-12 production+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0120162///positive regulation of cold-induced thermogenesis 14748 14748 'Gpr3' mRNA 20 12 5 0.53 0.31 0.14 0.34 0.35 0.31 0.326666667 0.333333333 15 15 13 12.33333333 14.33333333 0.825804051 0.220817676 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0040020///regulation of meiotic nuclear division+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0120162///positive regulation of cold-induced thermogenesis 14751 14751 'Gpi1' mRNA 6468.7 6613.43 6387.24 123.42 124.18 129.27 124.1 123.39 130.95 125.6233333 126.1466667 7483.26 7266.71 7645.75 6489.79 7465.24 8.60E-04 0.189944913 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0060170///ciliary membrane GO:0004347///glucose-6-phosphate isomerase activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0016853///isomerase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0048029///monosaccharide binding GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0005975///carbohydrate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0007611///learning or memory+++GO:0010595///positive regulation of endothelial cell migration+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0033574///response to testosterone+++GO:0034101///erythrocyte homeostasis+++GO:0035902///response to immobilization stress+++GO:0035994///response to muscle stretch+++GO:0042593///glucose homeostasis+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043278///response to morphine+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046686///response to cadmium ion+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0061620///glycolytic process through glucose-6-phosphate+++GO:0061621///canonical glycolysis 14755 14755 'Pigq' mRNA 2503 2519.01 2488 44.13 43.65 46.47 36.49 37.5 35.57 44.75 36.52 2366.96 2381.04 2242.05 2503.336667 2330.016667 0.13286334 -0.116007798 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004347///glucose-6-phosphate isomerase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008083///growth factor activity+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042169///SH2 domain binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding "GO:0000165///MAPK cascade+++GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0005975///carbohydrate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006506///GPI anchor biosynthetic process+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007611///learning or memory+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0033574///response to testosterone+++GO:0034101///erythrocyte homeostasis+++GO:0035556///intracellular signal transduction+++GO:0035902///response to immobilization stress+++GO:0035994///response to muscle stretch+++GO:0042501///serine phosphorylation of STAT protein+++GO:0042593///glucose homeostasis+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043278///response to morphine+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046686///response to cadmium ion+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0061620///glycolytic process through glucose-6-phosphate+++GO:0061621///canonical glycolysis" 14756 14756 'Gpld1' mRNA 2875.89 3195.1 3139.58 44.82 49.22 51.6 11.15 12.28 12.04 48.54666667 11.82333333 883.12 928.72 928.79 3070.19 913.5433333 2.05E-104 -1.762069125 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0004621///glycosylphosphatidylinositol phospholipase D activity+++GO:0004630///phospholipase D activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0017080///sodium channel regulator activity GO:0001503///ossification+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002062///chondrocyte differentiation+++GO:0002430///complement receptor mediated signaling pathway+++GO:0006507///GPI anchor release+++GO:0008285///negative regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0009749///response to glucose+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010983///positive regulation of high-density lipoprotein particle clearance+++GO:0032869///cellular response to insulin stimulus+++GO:0035690///cellular response to drug+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051047///positive regulation of secretion+++GO:0070633///transepithelial transport+++GO:0071241///cellular response to inorganic substance+++GO:0071277///cellular response to calcium ion+++GO:0071282///cellular response to iron(II) ion+++GO:0071397///cellular response to cholesterol+++GO:0071401///cellular response to triglyceride+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071467///cellular response to pH+++GO:1900076///regulation of cellular response to insulin stimulus 14758 14758 'Gpm6b' mRNA 10177.81 10350.23 10063.36 129.77 128.7 134.16 126.6 123.73 125.92 130.8766667 125.4166667 11677.99 11133.5 11328.41 10197.13333 11379.96667 0.006740474 0.14582169 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0001503///ossification+++GO:0015031///protein transport+++GO:0030501///positive regulation of bone mineralization+++GO:0031175///neuron projection development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051612///negative regulation of serotonin uptake+++GO:0051893///regulation of focal adhesion assembly+++GO:0085029///extracellular matrix assembly+++GO:2000009///negative regulation of protein localization to cell surface 14760 14760 'Gpr19' mRNA 229 238 260 7.41 7.78 9.02 4.26 3.38 4.48 8.07 4.04 143 116 149 242.3333333 136 1.16E-05 -0.849298235 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 14761 14761 'Gpr27' mRNA 226 196 77 4.63 3.96 1.67 0.43 0.66 0.39 3.42 0.493333333 24 36 21 166.3333333 27 1.41E-12 -2.613479957 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 14763 14763 'Gpr37' mRNA 3655 3810 3379 62.36 63.96 61.16 24.26 24.71 24.36 62.49333333 24.44333333 1636 1628 1591 3614.666667 1618.333333 6.89E-79 -1.169455087 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0030165///PDZ domain binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0036505///prosaposin receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0016358///dendrite development+++GO:0031987///locomotion involved in locomotory behavior+++GO:0042416///dopamine biosynthetic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045964///positive regulation of dopamine metabolic process+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 14764 14764 'Ptgdr2' mRNA 1 2.01 6.06 0.02 0.04 0.13 0.05 0.15 0.12 0.063333333 0.106666667 3.06 9.08 7.11 3.023333333 6.416666667 0.46657504 1.047849773 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0001785///prostaglandin J receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004956///prostaglandin D receptor activity+++GO:0004958///prostaglandin F receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0019722///calcium-mediated signaling+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:2000255///negative regulation of male germ cell proliferation 14766 14766 'Adgrg1' mRNA 710 765 635 10.7 11.49 10.33 10.47 10.74 10.25 10.84 10.48666667 790 795 745 703.3333333 776.6666667 0.242636187 0.134089789 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0097451///glial limiting end-foot GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0050840///extracellular matrix binding GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0010573///vascular endothelial growth factor production+++GO:0016477///cell migration+++GO:0021796///cerebral cortex regionalization+++GO:0021801///cerebral cortex radial glia guided migration+++GO:0021819///layer formation in cerebral cortex+++GO:0030154///cell differentiation+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0045785///positive regulation of cell adhesion+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0070528///protein kinase C signaling+++GO:0072520///seminiferous tubule development+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2001223///negative regulation of neuron migration 14768 14768 'Lancl1' mRNA 1134 1039 1107 13.72 12.35 14.21 10.45 11.37 11.34 13.42666667 11.05333333 995 1055 1040 1093.333333 1030 0.381053621 -0.098651255 00480///Glutathione metabolism GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane GO:0004364///glutathione transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0043295///glutathione binding+++GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0005975///carbohydrate metabolic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043523///regulation of neuron apoptotic process+++GO:1903203///regulation of oxidative stress-induced neuron death 14772 14772 'Grk4' mRNA 522.08 561.82 514.78 9.02 9.67 9.66 5.52 4.92 5.02 9.45 5.153333333 367.15 306.61 322.46 532.8933333 332.0733333 3.50E-08 -0.695060026 04062///Chemokine signaling pathway+++04144///Endocytosis+++04341///Hedgehog signaling pathway - fly+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0050254///rhodopsin kinase activity GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0002031///G protein-coupled receptor internalization+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0009966///regulation of signal transduction+++GO:0016310///phosphorylation+++GO:0031623///receptor internalization 14773 14773 'Grk5' mRNA 125 100 89 1.15 1.08 1.01 1.68 1.46 1.62 1.08 1.586666667 183 152 167 104.6666667 167.3333333 0.003297546 0.667035847 04062///Chemokine signaling pathway+++04144///Endocytosis+++04341///Hedgehog signaling pathway - fly+++05032///Morphine addiction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0047696///beta-adrenergic receptor kinase activity GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007217///tachykinin receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009966///regulation of signal transduction+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0046777///protein autophosphorylation+++GO:0051726///regulation of cell cycle+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 14775 14775 'Gpx1' mRNA 2953 3040 2852 178.78 181.98 183.2 570.14 643.19 592.57 181.32 601.9666667 10800 11877 10849 2948.333333 11175.33333 4.08E-206 1.912038525 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0097413///Lewy body GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0017124///SH3 domain binding+++GO:0047066///phospholipid-hydroperoxide glutathione peroxidase activity "GO:0000302///response to reactive oxygen species+++GO:0001659///temperature homeostasis+++GO:0001885///endothelial cell development+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007605///sensory perception of sound+++GO:0008283///cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009410///response to xenobiotic stimulus+++GO:0009609///response to symbiotic bacterium+++GO:0009611///response to wounding+++GO:0009636///response to toxic substance+++GO:0009650///UV protection+++GO:0010269///response to selenium ion+++GO:0010332///response to gamma radiation+++GO:0014902///myotube differentiation+++GO:0018158///protein oxidation+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0033194///response to hydroperoxide+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042311///vasodilation+++GO:0042542///response to hydrogen peroxide+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0043534///blood vessel endothelial cell migration+++GO:0045444///fat cell differentiation+++GO:0045454///cell redox homeostasis+++GO:0048741///skeletal muscle fiber development+++GO:0051402///neuron apoptotic process+++GO:0051450///myoblast proliferation+++GO:0051702///interaction with symbiont+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060047///heart contraction+++GO:0060055///angiogenesis involved in wound healing+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0071333///cellular response to glucose stimulus+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0098869///cellular oxidant detoxification+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway" 14776 14776 'Gpx2' mRNA 11994 12013 12060 707.75 700.66 755.08 261.82 265.08 252.24 721.1633333 259.7133333 5089 5023 4739 12022.33333 4950.333333 3.68E-112 -1.293152177 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity GO:0001659///temperature homeostasis+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0006979///response to oxidative stress+++GO:0009609///response to symbiotic bacterium+++GO:0051702///interaction with symbiont+++GO:0098869///cellular oxidant detoxification 14778 14778 'Gpx3' mRNA 23993 24737 22993 929.47 945.14 944.95 1970.32 2106.98 2003.31 939.8533333 2026.87 58427 60967 57473 23907.66667 58955.66667 7.62E-151 1.291502266 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding GO:0006749///glutathione metabolic process+++GO:0006979///response to oxidative stress+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification 14780 14780 'Gpx5' mRNA 0 1 1 0 0.04 0.04 0.06 0.13 0.1 0.026666667 0.096666667 2 4 3 0.666666667 3 0.332113246 2.156610028 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0097524///sperm plasma membrane GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity GO:0006979///response to oxidative stress+++GO:0034599///cellular response to oxidative stress+++GO:0098869///cellular oxidant detoxification 14782 14782 'Gsr' mRNA 592 628 345 12.28 12.82 7.59 7.37 11.52 10.2 10.89666667 9.696666667 409 624 548 521.6666667 527 0.941425519 0.019121425 00480///Glutathione metabolism+++04918///Thyroid hormone synthesis+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0009897///external side of plasma membrane "GO:0000166///nucleotide binding+++GO:0004362///glutathione-disulfide reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0042802///identical protein binding+++GO:0043295///glutathione binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0006749///glutathione metabolic process+++GO:0007283///spermatogenesis+++GO:0034599///cellular response to oxidative stress+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification 14783 14783 'Grb10' mRNA 291 345 312 3.05 3.56 3.51 3.32 2.99 3.17 3.373333333 3.16 359 319 332 316 336.6666667 0.678979458 0.079039505 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0001784///phosphotyrosine residue binding+++GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding" GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0010467///gene expression+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032868///response to insulin+++GO:0042326///negative regulation of phosphorylation+++GO:0042327///positive regulation of phosphorylation+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0070371///ERK1 and ERK2 cascade+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1904738///vascular associated smooth muscle cell migration 14784 14784 'Grb2' mRNA 408 453 340 8.67 9.58 7.83 13.29 11.79 13.07 8.693333333 12.71666667 704 611 670 400.3333333 661.6666667 2.99E-09 0.716514365 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04320///Dorso-ventral axis formation+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05231///Choline metabolism in cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008180///COP9 signalosome+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0070436///Grb2-EGFR complex "GO:0001784///phosphotyrosine residue binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0043560///insulin receptor substrate binding+++GO:0044877///protein-containing complex binding+++GO:0046875///ephrin receptor binding+++GO:0051219///phosphoprotein binding" GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007568///aging+++GO:0008286///insulin receptor signaling pathway+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0030154///cell differentiation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0031623///receptor internalization+++GO:0042770///signal transduction in response to DNA damage+++GO:0043408///regulation of MAPK cascade+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0071479///cellular response to ionizing radiation+++GO:2000379///positive regulation of reactive oxygen species metabolic process 14786 14786 'Grb7' mRNA 493 558 555 12.41 13.71 14.61 9.24 8.88 8.7 13.57666667 8.94 422 411 378 535.3333333 403.6666667 0.00129912 -0.42091374 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0017148///negative regulation of translation+++GO:0030335///positive regulation of cell migration+++GO:0034063///stress granule assembly+++GO:0046627///negative regulation of insulin receptor signaling pathway 14787 14787 'Rhpn1' mRNA 3291 3418 3253 80.61 82.52 84.49 21.23 19.06 18.86 82.54 19.71666667 996 873 857 3320.666667 908.6666667 2.81E-145 -1.882548827 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0071944///cell periphery GO:0005515///protein binding GO:0001822///kidney development+++GO:0003094///glomerular filtration+++GO:0007165///signal transduction+++GO:0048041///focal adhesion assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0097018///renal albumin absorption+++GO:0120039///plasma membrane bounded cell projection morphogenesis 14788 14788 'Gpr162' mRNA 123 135 76 2.22 2.41 1.46 1.18 1.03 0.78 2.03 0.996666667 75 64 48 111.3333333 62.33333333 0.006577157 -0.840023957 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 14789 14789 'P3h3' mRNA 260 226 197 5.1 4.36 4.1 5.16 4.85 5.65 4.52 5.22 303 278 321 227.6666667 300.6666667 0.021191816 0.392297443 GO:0005783///endoplasmic reticulum+++GO:1902494///catalytic complex "GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0008285///negative regulation of cell proliferation+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0032963///collagen metabolic process+++GO:0032964///collagen biosynthetic process 14790 14790 'Grcc10' mRNA 2807 2751 2769 399.35 390.35 418.21 284.18 319.58 304.03 402.6366667 302.5966667 2276 2486 2345 2775.666667 2369 0.001769516 -0.240270691 GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0009791///post-embryonic development+++GO:0014819///regulation of skeletal muscle contraction+++GO:0021540///corpus callosum morphogenesis+++GO:0021678///third ventricle development+++GO:0036343///psychomotor behavior+++GO:0048593///camera-type eye morphogenesis+++GO:0050890///cognition 14791 14791 'Emg1' mRNA 936.72 825.73 939.14 56.7 49.41 60.29 59.71 64.7 60.96 55.46666667 61.79 1131.13 1195.16 1116.9 900.53 1147.73 0.001351045 0.336459914 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0019843///rRNA binding+++GO:0042802///identical protein binding+++GO:0070037///rRNA (pseudouridine) methyltransferase activity GO:0001824///blastocyst development+++GO:0006364///rRNA processing+++GO:0017126///nucleologenesis+++GO:0032259///methylation+++GO:0042254///ribosome biogenesis+++GO:0070475///rRNA base methylation 14792 14792 'Lpcat3' mRNA 1000.28 1204.27 1031.86 24.08 28.6 26.64 36.72 38.53 37.37 26.44 37.54 1816.87 1808.84 1751.1 1078.803333 1792.27 1.15E-17 0.722096882 00564///Glycerophospholipid metabolism+++04216///Ferroptosis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0071617///lysophospholipid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0030258///lipid modification+++GO:0034378///chylomicron assembly+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0036335///intestinal stem cell homeostasis+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0045797///positive regulation of intestinal cholesterol absorption+++GO:0050728///negative regulation of inflammatory response+++GO:0090158///endoplasmic reticulum membrane organization+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:1901310///positive regulation of sterol regulatory element binding protein cleavage+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1905885///positive regulation of triglyceride transport 14793 14793 'Cdca3' mRNA 13 20 26 0.48 0.78 0.93 14.73 12.72 13.07 0.73 13.50666667 430 364 372 19.66666667 388.6666667 4.48E-64 4.288857445 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0051301///cell division 14794 14794 'Spsb2' mRNA 372 335 301 19.47 17.11 16.5 28.52 29.42 29.61 17.69333333 29.18333333 642 643 640 336 641.6666667 6.78E-15 0.924018011 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex "GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 14797 14797 'Tle5' mRNA 3641 3657 2638 146.84 145.49 112.87 126.76 143.95 138.54 135.0666667 136.4166667 3610 4000 3817 3312 3809 0.044182921 0.198055982 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003714///transcription corepressor activity+++GO:0005186///pheromone activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0070491///repressing transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007610///behavior+++GO:0010629///negative regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0032091///negative regulation of protein binding+++GO:0040008///regulation of growth+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045925///positive regulation of female receptivity+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070555///response to interleukin-1+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000210///positive regulation of anoikis" 14799 14799 'Gria1' mRNA 0 1 1 0 0.01 0.01 0.06 0.05 0.01 0.006666667 0.04 7 6 1 0.666666667 4.666666667 0.153813537 2.785074397 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05033///Nicotine addiction GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0008328///ionotropic glutamate receptor complex+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0031901///early endosome membrane+++GO:0032279///asymmetric synapse+++GO:0032281///AMPA glutamate receptor complex+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0032991///protein-containing complex+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044297///cell body+++GO:0044308///axonal spine+++GO:0044309///neuron spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098794///postsynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0099544///perisynaptic space GO:0001540///amyloid-beta binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0004971///AMPA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008179///adenylate cyclase binding+++GO:0015276///ligand-gated ion channel activity+++GO:0019865///immunoglobulin binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0031267///small GTPase binding+++GO:0031489///myosin V binding+++GO:0031681///G-protein beta-subunit binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0035254///glutamate receptor binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0051018///protein kinase A binding+++GO:0097110///scaffold protein binding+++GO:0099583///neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001919///regulation of receptor recycling+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007616///long-term memory+++GO:0009636///response to toxic substance+++GO:0019228///neuronal action potential+++GO:0031623///receptor internalization+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0045838///positive regulation of membrane potential+++GO:0048167///regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050806///positive regulation of synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060292///long-term synaptic depression+++GO:0071242///cellular response to ammonium ion+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration 14800 14800 'Gria2' mRNA 104 103 97 1.1 1.13 1 0.38 0.42 0.35 1.076666667 0.383333333 34 54 41 101.3333333 43 5.18E-05 -1.244708004 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0032279///asymmetric synapse+++GO:0032281///AMPA glutamate receptor complex+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0036477///somatodendritic compartment+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0099544///perisynaptic space GO:0000149///SNARE binding+++GO:0001540///amyloid-beta binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0004971///AMPA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0019865///immunoglobulin binding+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0035254///glutamate receptor binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0051117///ATPase binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001919///regulation of receptor recycling+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0031623///receptor internalization+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0045184///establishment of protein localization+++GO:0050806///positive regulation of synaptic transmission+++GO:0051262///protein tetramerization+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential" 14802 14802 'Gria4' mRNA 81 60 34 0.86 0.59 0.51 0.23 0.17 0.33 0.653333333 0.243333333 18 19 16 58.33333333 17.66666667 1.56E-04 -1.722251387 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032281///AMPA glutamate receptor complex+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004971///AMPA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential" 14803 14803 'Grid1' mRNA 9 6 8 0.14 0.08 0.1 0.02 0.03 0.03 0.106666667 0.026666667 2 2 2 7.666666667 2 0.119263046 -1.953610713 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0035176///social behavior+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential" 14804 14804 'Grid2' mRNA 73 73 63 0.58 0.57 0.5 0.05 0.06 0.05 0.55 0.053333333 8 9 7 69.66666667 8 1.10E-11 -3.131410592 04080///Neuroactive ligand-receptor interaction+++04730///Long-term depression GO:0005886///plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0036477///somatodendritic compartment+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0030165///PDZ domain binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0097110///scaffold protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0010975///regulation of neuron projection development+++GO:0021707///cerebellar granule cell differentiation+++GO:0034220///ion transmembrane transport+++GO:0034613///cellular protein localization+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0043523///regulation of neuron apoptotic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051965///positive regulation of synapse assembly+++GO:0060079///excitatory postsynaptic potential+++GO:0060134///prepulse inhibition+++GO:0099151///regulation of postsynaptic density assembly+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1904861///excitatory synapse assembly+++GO:1905606///regulation of presynapse assembly" 14805 14805 'Grik1' mRNA 33 46 39 0.51 0.7 0.65 0.25 0.12 0.06 0.62 0.143333333 19 8 5 39.33333333 10.66666667 9.35E-04 -1.901549116 04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005886///plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0016595///glutamate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:1901363///heterocyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0007399///nervous system development+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0015813///L-glutamate transmembrane transport+++GO:0030534///adult behavior+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048266///behavioral response to pain+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051899///membrane depolarization+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential" 14806 14806 'Grik2' mRNA 18 16 23 0.13 0.13 0.32 0.11 0.17 0.11 0.193333333 0.13 14 17 15 19 15.33333333 0.66961242 -0.326951278 04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0030165///PDZ domain binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001662///behavioral fear response+++GO:0006811///ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006886///intracellular protein transport+++GO:0007268///chemical synaptic transmission+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0043113///receptor clustering+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046328///regulation of JNK cascade+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050806///positive regulation of synaptic transmission+++GO:0051402///neuron apoptotic process+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0099505///regulation of presynaptic membrane potential+++GO:0120169///detection of cold stimulus involved in thermoception" 14807 14807 'Grik3' mRNA 34 26 17 0.21 0.17 0.11 0.09 0.08 0.1 0.163333333 0.09 18 15 20 25.66666667 17.66666667 0.390537757 -0.542163709 04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0038023///signaling receptor activity+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0099505///regulation of presynaptic membrane potential" 14809 14809 'Grik5' mRNA 216.42 233.09 151.39 1.8 1.73 1.28 1.04 1.18 1.04 1.603333333 1.086666667 146.1 147.48 130.92 200.3 141.5 0.018797231 -0.508433673 04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0017124///SH3 domain binding+++GO:0030165///PDZ domain binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006621///protein retention in ER lumen+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0043113///receptor clustering+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051649///establishment of localization in cell+++GO:0060079///excitatory postsynaptic potential+++GO:0071333///cellular response to glucose stimulus" 14810 14810 'Grin1' mRNA 101 76 65 1.38 1.01 0.97 0.09 0.06 0.01 1.12 0.053333333 7 5 1 80.66666667 4.333333333 1.57E-14 -4.227256539 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030658///transport vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0032590///dendrite membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044307///dendritic branch+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0001540///amyloid-beta binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015276///ligand-gated ion channel activity+++GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0019899///enzyme binding+++GO:0019902///phosphatase binding+++GO:0022843///voltage-gated cation channel activity+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0035254///glutamate receptor binding+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding+++GO:0044877///protein-containing complex binding+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001661///conditioned taste aversion+++GO:0001964///startle response+++GO:0001967///suckling behavior+++GO:0001975///response to amphetamine+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007616///long-term memory+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0008355///olfactory learning+++GO:0008542///visual learning+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010646///regulation of cell communication+++GO:0010942///positive regulation of cell death+++GO:0018964///propylene metabolic process+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0021586///pons maturation+++GO:0021987///cerebral cortex development+++GO:0034220///ion transmembrane transport+++GO:0035176///social behavior+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0043065///positive regulation of apoptotic process+++GO:0043278///response to morphine+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0045471///response to ethanol+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048167///regulation of synaptic plasticity+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048511///rhythmic process+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050905///neuromuscular process+++GO:0051290///protein heterotetramerization+++GO:0051963///regulation of synapse assembly+++GO:0055074///calcium ion homeostasis+++GO:0060079///excitatory postsynaptic potential+++GO:0060134///prepulse inhibition+++GO:0060179///male mating behavior+++GO:0065003///protein-containing complex assembly+++GO:0097553///calcium ion transmembrane import into cytosol+++GO:0099505///regulation of presynaptic membrane potential+++GO:1900149///positive regulation of Schwann cell migration+++GO:1902952///positive regulation of dendritic spine maintenance+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903539///protein localization to postsynaptic membrane+++GO:1905429///response to glycine+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2001056///positive regulation of cysteine-type endopeptidase activity" 14811 14811 'Grin2a' mRNA 1 0 0 0 0 0 0.01 0 0 0 0.003333333 2 0 0 0.333333333 0.666666667 0.863090843 0.855229838 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097060///synaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0015276///ligand-gated ion channel activity+++GO:0016595///glutamate binding+++GO:0019901///protein kinase binding+++GO:0022843///voltage-gated cation channel activity+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0035254///glutamate receptor binding+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0051117///ATPase binding+++GO:0097110///scaffold protein binding+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001508///action potential+++GO:0001964///startle response+++GO:0001975///response to amphetamine+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0009410///response to xenobiotic stimulus+++GO:0009611///response to wounding+++GO:0010942///positive regulation of cell death+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0022008///neurogenesis+++GO:0030431///sleep+++GO:0033058///directional locomotion+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0040011///locomotion+++GO:0042177///negative regulation of protein catabolic process+++GO:0042391///regulation of membrane potential+++GO:0042417///dopamine metabolic process+++GO:0042428///serotonin metabolic process+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0048167///regulation of synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048511///rhythmic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0071230///cellular response to amino acid stimulus+++GO:0071294///cellular response to zinc ion+++GO:0097061///dendritic spine organization+++GO:0097553///calcium ion transmembrane import into cytosol+++GO:0099505///regulation of presynaptic membrane potential+++GO:1903539///protein localization to postsynaptic membrane+++GO:2000310///regulation of NMDA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential 14812 14812 'Grin2b' mRNA 1 0 6 0 0 0.04 0.01 0.02 0.03 0.013333333 0.02 4 5 7 2.333333333 5.333333333 0.496584731 1.13880952 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030658///transport vesicle membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044307///dendritic branch+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097060///synaptic membrane+++GO:0097440///apical dendrite+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005102///signaling receptor binding+++GO:0005149///interleukin-1 receptor binding+++GO:0005216///ion channel activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008270///zinc ion binding+++GO:0015276///ligand-gated ion channel activity+++GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0031749///D2 dopamine receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0036094///small molecule binding+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0097110///scaffold protein binding+++GO:0099529///neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:0099583///neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:1901363///heterocyclic compound binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001508///action potential+++GO:0001662///behavioral fear response+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001964///startle response+++GO:0001967///suckling behavior+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007423///sensory organ development+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0009790///embryo development+++GO:0010243///response to organonitrogen compound+++GO:0010738///regulation of protein kinase A signaling+++GO:0010942///positive regulation of cell death+++GO:0014049///positive regulation of glutamate secretion+++GO:0019722///calcium-mediated signaling+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0042596///fear response+++GO:0043113///receptor clustering+++GO:0043408///regulation of MAPK cascade+++GO:0045471///response to ethanol+++GO:0046960///sensitization+++GO:0048167///regulation of synaptic plasticity+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048266///behavioral response to pain+++GO:0048511///rhythmic process+++GO:0050806///positive regulation of synaptic transmission+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051290///protein heterotetramerization+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0097553///calcium ion transmembrane import into cytosol+++GO:0098989///NMDA selective glutamate receptor signaling pathway+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1901216///positive regulation of neuron death+++GO:1902951///negative regulation of dendritic spine maintenance+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 14813 14813 'Grin2c' mRNA 30 63 16 0.33 0.56 0.12 0.06 0.05 0.04 0.336666667 0.05 6 5 6 36.33333333 5.666666667 8.88E-05 -2.67109512 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0030165///PDZ domain binding+++GO:0038023///signaling receptor activity+++GO:0047485///protein N-terminus binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001964///startle response+++GO:0006811///ion transport+++GO:0007626///locomotory behavior+++GO:0009611///response to wounding+++GO:0019722///calcium-mediated signaling+++GO:0033058///directional locomotion+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0042177///negative regulation of protein catabolic process+++GO:0042391///regulation of membrane potential+++GO:0048167///regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050885///neuromuscular process controlling balance+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0097553///calcium ion transmembrane import into cytosol+++GO:1903539///protein localization to postsynaptic membrane 14814 14814 'Grin2d' mRNA 104 86 34 1.49 1.14 0.48 0.09 0.1 0.18 1.036666667 0.123333333 13 13 17 74.66666667 14.33333333 4.24E-07 -2.37419773 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0016595///glutamate binding+++GO:0022843///voltage-gated cation channel activity+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0001964///startle response+++GO:0006811///ion transport+++GO:0008344///adult locomotory behavior+++GO:0019722///calcium-mediated signaling+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051930///regulation of sensory perception of pain+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0097553///calcium ion transmembrane import into cytosol" 14815 14815 'Nr3c1' mRNA 1166 1295 1003 9.61 10.68 8.8 9.37 9.63 10.54 9.696666667 9.846666667 1311 1329 1427 1154.666667 1355.666667 0.020738402 0.224318832 04080///Neuroactive ligand-receptor interaction "GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0004879///nuclear receptor activity+++GO:0004883///glucocorticoid receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031072///heat shock protein binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding+++GO:1990239///steroid hormone binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006111///regulation of gluconeogenesis+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008211///glucocorticoid metabolic process+++GO:0010906///regulation of glucose metabolic process+++GO:0014049///positive regulation of glutamate secretion+++GO:0030325///adrenal gland development+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0031914///negative regulation of synaptic plasticity+++GO:0031946///regulation of glucocorticoid biosynthetic process+++GO:0042127///regulation of cell proliferation+++GO:0042711///maternal behavior+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043116///negative regulation of vascular permeability+++GO:0043402///glucocorticoid mediated signaling pathway+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046685///response to arsenic-containing substance+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0060603///mammary gland duct morphogenesis+++GO:0060999///positive regulation of dendritic spine development+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1900170///negative regulation of glucocorticoid mediated signaling pathway+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway" 14816 14816 'Grm1' mRNA 1 2 3 0.01 0.02 0.03 0.02 0 0.01 0.02 0.01 2 0 1 2 1 0.695559642 -1.040102481 04020///Calcium signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04540///Gap junction+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04915///Estrogen signaling pathway+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038038///G protein-coupled receptor homodimeric complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0001639///PLC activating G protein-coupled glutamate receptor activity+++GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008066///glutamate receptor activity+++GO:0030331///estrogen receptor binding+++GO:0042802///identical protein binding+++GO:0098872///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:0099530///G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential+++GO:0099583///neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration "GO:0000186///activation of MAPKK activity+++GO:0000187///activation of MAPK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007206///phospholipase C-activating G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007626///locomotory behavior+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0043408///regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051930///regulation of sensory perception of pain+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071257///cellular response to electrical stimulus+++GO:0098712///L-glutamate import across plasma membrane+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration" 14823 14823 'Grm8' mRNA 5 2 0 0.1 0.03 0 0 0.03 0.07 0.043333333 0.033333333 0 2 3 2.333333333 1.666666667 0.863090843 -0.45687259 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0001642///group III metabotropic glutamate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008066///glutamate receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0035249///synaptic transmission, glutamatergic+++GO:0046928///regulation of neurotransmitter secretion+++GO:0050896///response to stimulus+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:2000300///regulation of synaptic vesicle exocytosis" 14824 14824 'Grn' mRNA 3994 4103 4004 105.07 106.31 111.74 745.23 748.09 733.23 107.7066667 742.1833333 32573 31924 31022 4033.666667 31839.66667 0 2.96831157 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0098793///presynapse GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding GO:0001835///blastocyst hatching+++GO:0002265///astrocyte activation involved in immune response+++GO:0002282///microglial cell activation involved in immune response+++GO:0007040///lysosome organization+++GO:0007041///lysosomal transport+++GO:0007042///lysosomal lumen acidification+++GO:0007165///signal transduction+++GO:0007566///embryo implantation+++GO:0008284///positive regulation of cell proliferation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010976///positive regulation of neuron projection development+++GO:0030335///positive regulation of cell migration+++GO:0032355///response to estradiol+++GO:0035641///locomotory exploration behavior+++GO:0035988///chondrocyte proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045824///negative regulation of innate immune response+++GO:0048488///synaptic vesicle endocytosis+++GO:0048680///positive regulation of axon regeneration+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0050821///protein stabilization+++GO:0051346///negative regulation of hydrolase activity+++GO:0060041///retina development in camera-type eye+++GO:0060179///male mating behavior+++GO:0060266///negative regulation of respiratory burst involved in inflammatory response+++GO:0060999///positive regulation of dendritic spine development+++GO:0061351///neural precursor cell proliferation+++GO:0106016///positive regulation of inflammatory response to wounding+++GO:1900426///positive regulation of defense response to bacterium+++GO:1902564///negative regulation of neutrophil activation+++GO:1903334///positive regulation of protein folding+++GO:1903979///negative regulation of microglial cell activation+++GO:1905146///lysosomal protein catabolic process+++GO:1905247///positive regulation of aspartic-type peptidase activity+++GO:1905671///regulation of lysosome organization+++GO:1905673///positive regulation of lysosome organization 14825 14825 'Cxcl1' mRNA 23 14 16 1.56 0.94 1.15 10.22 8.31 9.05 1.216666667 9.193333333 173 137 148 17.66666667 152.6666667 2.34E-22 3.098545909 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05134///Legionellosis+++05146///Amoebiasis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008083///growth factor activity+++GO:0045236///CXCR chemokine receptor binding GO:0002237///response to molecule of bacterial origin+++GO:0002526///acute inflammatory response+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010765///positive regulation of sodium ion transport+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0032930///positive regulation of superoxide anion generation+++GO:0043268///positive regulation of potassium ion transport+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070965///positive regulation of neutrophil mediated killing of fungus+++GO:0071222///cellular response to lipopolysaccharide+++GO:1902035///positive regulation of hematopoietic stem cell proliferation 14827 14827 'Pdia3' mRNA 10695.73 11202.81 10298.59 224.43 231.39 229.23 317.84 277.41 292.63 228.35 295.96 17424.96 14851.91 15532.95 10732.37667 15936.60667 5.17E-23 0.557834884 04141///Protein processing in endoplasmic reticulum+++04612///Antigen processing and presentation+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0042470///melanosome+++GO:0042824///MHC class I peptide loading complex+++GO:0042825///TAP complex+++GO:0043209///myelin sheath GO:0003756///protein disulfide isomerase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0019153///protein-disulfide reductase (glutathione) activity+++GO:0042288///MHC class I protein binding+++GO:0042802///identical protein binding GO:0006457///protein folding+++GO:0006508///proteolysis+++GO:0034976///response to endoplasmic reticulum stress+++GO:0071305///cellular response to vitamin D+++GO:0098761///cellular response to interleukin-7+++GO:1903334///positive regulation of protein folding+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 14828 14828 'Hspa5' mRNA 13661.77 14258.93 14321.32 298.34 306.66 331.83 408.46 424.64 410.58 312.2766667 414.56 21509.8 21847.07 20924.4 14080.67333 21427.09 1.77E-24 0.592670342 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04612///Antigen processing and presentation+++04918///Thyroid hormone synthesis+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043022///ribosome binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding "GO:0001554///luteolysis+++GO:0006983///ER overload response+++GO:0009314///response to radiation+++GO:0010976///positive regulation of neuron projection development+++GO:0021589///cerebellum structural organization+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031204///posttranslational protein targeting to membrane, translocation+++GO:0031333///negative regulation of protein complex assembly+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035437///maintenance of protein localization in endoplasmic reticulum+++GO:0035690///cellular response to drug+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0040019///positive regulation of embryonic development+++GO:0042026///protein refolding+++GO:0042149///cellular response to glucose starvation+++GO:0042220///response to cocaine+++GO:0043066///negative regulation of apoptotic process+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051402///neuron apoptotic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071236///cellular response to antibiotic+++GO:0071277///cellular response to calcium ion+++GO:0071287///cellular response to manganese ion+++GO:0071320///cellular response to cAMP+++GO:0071353///cellular response to interleukin-4+++GO:0071480///cellular response to gamma radiation+++GO:0097501///stress response to metal ion+++GO:1901998///toxin transport+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response+++GO:1904313///response to methamphetamine hydrochloride+++GO:1990090///cellular response to nerve growth factor stimulus" 14829 14829 'Grpr' mRNA 1 3 2 0.02 0.06 0.05 0.02 0.04 0 0.043333333 0.02 1 2 0 2 1 0.707573642 -1.005359275 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004946///bombesin receptor activity+++GO:0005515///protein binding+++GO:0008188///neuropeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007611///learning or memory+++GO:0031989///bombesin receptor signaling pathway+++GO:0035176///social behavior+++GO:0036343///psychomotor behavior+++GO:0042127///regulation of cell proliferation+++GO:0043207///response to external biotic stimulus+++GO:0061744///motor behavior 14836 14836 'Gsc' mRNA 0 4 2 0 0.21 0.11 0 0 0.05 0.106666667 0.016666667 0 0 1 2 0.333333333 0.416528164 -2.487276284 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009653///anatomical structure morphogenesis+++GO:0014036///neural crest cell fate specification+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030900///forebrain development+++GO:0042474///middle ear morphogenesis+++GO:0043583///ear development+++GO:0048644///muscle organ morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis" 14840 14840 'Gsg1' mRNA 3 2 0 0.15 0.1 0 0.78 0.18 0.54 0.083333333 0.5 18 4 12 1.666666667 11.33333333 0.026063117 2.761667549 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0070063///RNA polymerase binding GO:0008150///biological_process 14841 14841 'Haspin' mRNA 19 8 10 0.37 0.15 0.21 1.98 2.52 1.62 0.243333333 2.04 116 144 92 12.33333333 117.3333333 2.03E-16 3.241882174 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0072354///histone kinase activity (H3-T3 specific) "GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0071459///protein localization to chromosome, centromeric region+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000751///histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore" 14852 14852 'Gspt1' mRNA 744 894 489 5.76 6.8 4.02 4.8 4.93 5.69 5.526666667 5.14 714 716 820 709 750 0.691544474 0.081207914 03015///mRNA surveillance pathway GO:0005829///cytosol+++GO:0018444///translation release factor complex GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003747///translation release factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0002184///cytoplasmic translational termination+++GO:0006412///translation+++GO:0006414///translational elongation+++GO:0006449///regulation of translational termination+++GO:0006479///protein methylation" 14853 14853 'Gspt2' mRNA 163 143 150 3.64 3.15 3.56 4.12 3.02 3.35 3.45 3.496666667 212 152 167 152 177 0.400556887 0.204589196 03015///mRNA surveillance pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0018444///translation release factor complex GO:0000166///nucleotide binding+++GO:0003747///translation release factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0002184///cytoplasmic translational termination+++GO:0006412///translation+++GO:0007049///cell cycle" 14854 14854 'Gss' mRNA 837 891 765 25.23 26.39 24.42 24.89 27.87 25.44 25.34666667 26.06666667 946 1038 948 831 977.3333333 0.027600072 0.225205552 00270///Cysteine and methionine metabolism+++00480///Glutathione metabolism+++01240///Biosynthesis of cofactors+++04216///Ferroptosis GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004363///glutathione synthase activity+++GO:0005524///ATP binding+++GO:0016594///glycine binding+++GO:0016874///ligase activity+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding+++GO:0046872///metal ion binding GO:0006750///glutathione biosynthetic process+++GO:0007568///aging+++GO:0009410///response to xenobiotic stimulus+++GO:0031667///response to nutrient levels+++GO:0034612///response to tumor necrosis factor+++GO:0043200///response to amino acid+++GO:0046686///response to cadmium ion 14857 14857 'Gsta1' mRNA 154.83 247.93 199.12 11.97 18.99 16.34 8.83 11.66 10.33 15.76666667 10.27333333 130.71 168.16 147.73 200.6266667 148.8666667 0.065555801 -0.439921389 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005504///fatty acid binding+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0035731///dinitrosyl-iron complex binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009617///response to bacterium+++GO:0035634///response to stilbenoid+++GO:0042178///xenobiotic catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process 14858 14858 'Gsta2' mRNA 270.03 277.53 268.15 21.07 21.45 22.13 9.8 9.65 8.23 21.55 9.226666667 143.89 137.93 117.5 271.9033333 133.1066667 3.48E-09 -1.050134841 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005504///fatty acid binding+++GO:0016740///transferase activity+++GO:0035731///dinitrosyl-iron complex binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009617///response to bacterium+++GO:0035634///response to stilbenoid+++GO:0042178///xenobiotic catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process 14859 14859 'Gsta3' mRNA 39 21 37 1.82 0.92 1.79 1.01 0.97 0.94 1.51 0.973333333 26 25 24 32.33333333 25 0.499879975 -0.389943382 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity GO:0001657///ureteric bud development+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0046223///aflatoxin catabolic process 14860 14860 'Gsta4' mRNA 6537 6533 6538 441.02 436.04 468.03 294.66 304.95 287.23 448.3633333 295.6133333 5006 5049 4715 6536 4923.333333 5.88E-12 -0.421432845 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005504///fatty acid binding+++GO:0015643///toxic substance binding+++GO:0016740///transferase activity+++GO:0097159///organic cyclic compound binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009635///response to herbicide+++GO:0010043///response to zinc ion+++GO:0035094///response to nicotine+++GO:0043651///linoleic acid metabolic process+++GO:0071285///cellular response to lithium ion+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process 14862 14862 'Gstm1' mRNA 7196 7316 7326 337.54 338.32 364.34 280.03 292.3 276.48 346.7333333 282.9366667 6857 6984 6551 7279.333333 6797.333333 0.097603114 -0.111564957 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0016151///nickel cation binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0018916///nitrobenzene metabolic process+++GO:0035690///cellular response to drug+++GO:0042178///xenobiotic catabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0070458///cellular detoxification of nitrogen compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1901687///glutathione derivative biosynthetic process 14863 14863 'Gstm2' mRNA 2345.99 2447 2411.98 144.41 148.93 157.54 104.79 115.32 116.03 150.2933333 112.0466667 1952 2094 2088.99 2401.656667 2044.996667 0.002008881 -0.243583216 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0070458///cellular detoxification of nitrogen compound+++GO:1901687///glutathione derivative biosynthetic process 14864 14864 'Gstm3' mRNA 3 1 1 0.15 0.05 0.05 0.04 0 0.05 0.083333333 0.03 1 0 1 1.666666667 0.666666667 0.650290036 -1.332879466 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0009617///response to bacterium+++GO:0018916///nitrobenzene metabolic process+++GO:0035690///cellular response to drug+++GO:0042178///xenobiotic catabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0070458///cellular detoxification of nitrogen compound+++GO:0071407///cellular response to organic cyclic compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1901687///glutathione derivative biosynthetic process 14865 14865 'Gstm4' mRNA 419.01 374 399.02 15.13 13.69 16.05 15.05 13.28 15.06 14.95666667 14.46333333 481 394 455.01 397.3433333 443.3366667 0.361958225 0.143771531 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0004464///leukotriene-C4 synthase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006629///lipid metabolic process+++GO:0006749///glutathione metabolic process+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0042759///long-chain fatty acid biosynthetic process 14866 14866 'Gstm5' mRNA 2055 2017 2007 147.77 143.56 153.14 138.13 140.22 145.07 148.1566667 141.14 2201 2177 2233 2026.333333 2203.666667 0.167052003 0.108858167 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035686///sperm fibrous sheath+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006749///glutathione metabolic process+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0043627///response to estrogen+++GO:0070458///cellular detoxification of nitrogen compound 14867 14867 'Gstm6' mRNA 30 63 28 1.76 3.33 1.68 2.68 3.28 3.3 2.256666667 3.086666667 58 66 66 40.33333333 63.33333333 0.120314848 0.65164386 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0070458///cellular detoxification of nitrogen compound+++GO:1901687///glutathione derivative biosynthetic process 14869 14869 'Gstp2' mRNA 12.63 6.49 12.46 1.17 0.6 1.22 5.37 4.26 5.35 0.996666667 4.993333333 66.39 51.25 63.85 10.52666667 60.49666667 5.78E-08 2.566541912 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0097057///TRAF2-GSTP1 complex GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005504///fatty acid binding+++GO:0015643///toxic substance binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0035730///S-nitrosoglutathione binding+++GO:0035731///dinitrosyl-iron complex binding+++GO:0097159///organic cyclic compound binding GO:0006469///negative regulation of protein kinase activity+++GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009890///negative regulation of biosynthetic process+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043508///negative regulation of JUN kinase activity+++GO:0043651///linoleic acid metabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0071672///negative regulation of smooth muscle cell chemotaxis+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 14870 14870 'Gstp1' mRNA 5467.41 5391.51 5139.3 513.24 502.15 512 595.62 629.17 619.91 509.13 614.9 7257.35 7462.03 7289.78 5332.74 7336.386667 2.52E-16 0.449268563 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0097057///TRAF2-GSTP1 complex GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005504///fatty acid binding+++GO:0008144///drug binding+++GO:0008432///JUN kinase binding+++GO:0015643///toxic substance binding+++GO:0016740///transferase activity+++GO:0019207///kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0035730///S-nitrosoglutathione binding+++GO:0035731///dinitrosyl-iron complex binding+++GO:0097159///organic cyclic compound binding GO:0000302///response to reactive oxygen species+++GO:0002674///negative regulation of acute inflammatory response+++GO:0006469///negative regulation of protein kinase activity+++GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009636///response to toxic substance+++GO:0009890///negative regulation of biosynthetic process+++GO:0014003///oligodendrocyte development+++GO:0031100///animal organ regeneration+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032869///cellular response to insulin stimulus+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033591///response to L-ascorbic acid+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043200///response to amino acid+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043508///negative regulation of JUN kinase activity+++GO:0043651///linoleic acid metabolic process+++GO:0045471///response to ethanol+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0051122///hepoxilin biosynthetic process+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070664///negative regulation of leukocyte proliferation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071460///cellular response to cell-matrix adhesion+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0071672///negative regulation of smooth muscle cell chemotaxis+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:2000429///negative regulation of neutrophil aggregation+++GO:2000469///negative regulation of peroxidase activity+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 14871 14871 'Gstt1' mRNA 1621 1739 1617 101.07 107.45 105.78 134.96 139.83 138.5 104.7666667 137.7633333 2505 2520 2448 1659 2491 9.35E-17 0.575144261 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016740///transferase activity+++GO:0047651///alkylhalidase activity GO:0006304///DNA modification+++GO:0006749///glutathione metabolic process+++GO:0007568///aging+++GO:0009751///response to salicylic acid+++GO:0010269///response to selenium ion+++GO:0014070///response to organic cyclic compound+++GO:0018900///dichloromethane metabolic process+++GO:0033197///response to vitamin E+++GO:0042493///response to drug+++GO:0098869///cellular oxidant detoxification 14872 14872 'Gstt2' mRNA 672 678 648 30.38 30.83 33.38 40.25 45.89 44.47 31.53 43.53666667 1030 1053 1042 666 1041.666667 5.90E-12 0.634159984 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016740///transferase activity GO:0006749///glutathione metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1990830///cellular response to leukemia inhibitory factor 14873 14873 'Gsto1' mRNA 185 159 157 9.67 8.21 8.71 50.52 53.81 43.3 8.863333333 49.21 1109 1152 919 167 1060 5.85E-92 2.655398273 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005604///basement membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0031965///nuclear membrane+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0004364///glutathione transferase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0045174///glutathione dehydrogenase (ascorbate) activity+++GO:0050610///methylarsonate reductase activity GO:0006749///glutathione metabolic process+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0019852///L-ascorbic acid metabolic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:0042178///xenobiotic catabolic process+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0071243///cellular response to arsenic-containing substance+++GO:0098869///cellular oxidant detoxification 14874 14874 'Gstz1' mRNA 1156.65 1228.63 1111.99 41.05 42.24 42.06 28.02 28.02 30.22 41.78333333 28.75333333 905.75 886.29 948.37 1165.756667 913.47 3.84E-05 -0.362321208 00350///Tyrosine metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0004364///glutathione transferase activity+++GO:0016034///maleylacetoacetate isomerase activity+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006559///L-phenylalanine catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0006749///glutathione metabolic process+++GO:0008152///metabolic process+++GO:0009072///aromatic amino acid family metabolic process 14884 14884 'Gtf2h1' mRNA 734 703 750 14.78 13.91 15.98 18.57 18.46 20.17 14.89 19.06666667 1063 1032 1118 729 1071 3.36E-08 0.541536174 03022///Basal transcription factors+++03420///Nucleotide excision repair+++05203///Viral carcinogenesis GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005675///transcription factor TFIIH holo complex GO:0003682///chromatin binding+++GO:0046966///thyroid hormone receptor binding "GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006351///transcription, DNA-templated+++GO:0006360///transcription by RNA polymerase I+++GO:0006366///transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:1990830///cellular response to leukemia inhibitory factor" 14885 14885 'Gtf2h4' mRNA 363 388 312 12.49 13.15 11.4 13.08 11.77 11.9 12.34666667 12.25 437 383 384 354.3333333 401.3333333 0.268871393 0.170176196 03022///Basal transcription factors+++03420///Nucleotide excision repair+++05203///Viral carcinogenesis GO:0000438///core TFIIH complex portion of holo TFIIH complex+++GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0016607///nuclear speck GO:0001671///ATPase activator activity+++GO:0003690///double-stranded DNA binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006366///transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0050790///regulation of catalytic activity+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain 14886 14886 'Gtf2i' mRNA 10453 10716 7012 123.04 124.49 86.48 37.04 44.34 42.9 111.3366667 41.42666667 3588 4124 3998 9393.666667 3903.333333 1.41E-13 -1.267706692 03022///Basal transcription factors+++04022///cGMP-PKG signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043025///neuronal cell body "GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0009790///embryo development+++GO:0014886///transition between slow and fast fiber+++GO:0016525///negative regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0100026///positive regulation of DNA repair by transcription from RNA polymerase II promoter" 14894 14894 'Cfap20' mRNA 1745 1822 1818 81.62 84.12 90.21 56.9 56.31 55.76 85.31666667 56.32333333 1396 1348 1323 1795 1355.666667 1.26E-07 -0.418118132 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0018095///protein polyglutamylation+++GO:0060271///cilium assembly+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:2000147///positive regulation of cell motility+++GO:2000253///positive regulation of feeding behavior 14897 14897 'Trip12' mRNA 1978 2032 1825 10.63 10.74 10.41 11.18 9.72 10.64 10.59333333 10.51333333 2392 2036 2210 1945 2212.666667 0.023936445 0.174418364 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046966///thyroid hormone receptor binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0045995///regulation of embryonic development+++GO:1901315///negative regulation of histone H2A K63-linked ubiquitination+++GO:2000779///regulation of double-strand break repair+++GO:2000780///negative regulation of double-strand break repair 14904 14904 'Gtpbp1' mRNA 1805 1999 1906 28.89 31.45 32.34 16.12 14.48 15.73 30.89333333 15.44333333 1158 1016 1094 1903.333333 1089.333333 2.04E-23 -0.818375958 GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006414///translational elongation+++GO:0046039///GTP metabolic process+++GO:0061014///positive regulation of mRNA catabolic process 14911 14911 'Thumpd3' mRNA 477 432 499 12.55 11.4 13.88 15.41 15.38 16.54 12.61 15.77666667 673 653 695 469.3333333 673.6666667 3.14E-05 0.506720293 GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0016740///transferase activity GO:0030488///tRNA methylation+++GO:0032259///methylation 14912 14912 'Nkx6-2' mRNA 4.24 3.09 3.08 0.12 0.08 0.09 0 0.04 0.08 0.096666667 0.04 0 1 3.32 3.47 1.44 0.514337137 -1.324142762 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010454///negative regulation of cell fate commitment+++GO:0010455///positive regulation of cell fate commitment+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0031641///regulation of myelination+++GO:0045686///negative regulation of glial cell differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048709///oligodendrocyte differentiation+++GO:0050885///neuromuscular process controlling balance" 14913 14913 'Guca1a' mRNA 33 26 25 2.82 2.21 2.27 4.19 5.76 5.27 2.433333333 5.073333333 56 75 68 28 66.33333333 0.001039707 1.237032792 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0016020///membrane+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0008048///calcium sensitive guanylate cyclase activator activity+++GO:0030249///guanylate cyclase regulator activity+++GO:0046872///metal ion binding GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0031282///regulation of guanylate cyclase activity+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0050896///response to stimulus+++GO:0071277///cellular response to calcium ion 14917 14917 'Gucy2c' mRNA 0 3 4 0 0.04 0.06 0.04 0.02 0 0.033333333 0.02 3 2 0 2.333333333 1.666666667 0.849752509 -0.524803833 00230///Purine metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0015643///toxic substance binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0016941///natriuretic peptide receptor activity+++GO:0017046///peptide hormone binding GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0009636///response to toxic substance+++GO:0035556///intracellular signal transduction+++GO:0042127///regulation of cell proliferation 14918 14918 'Gucy2d' mRNA 85 107 88 1.27 1.57 1.39 0.23 0.09 0.07 1.41 0.13 18 7 5 93.33333333 10 1.33E-13 -3.237909244 00230///Purine metabolism+++04740///Olfactory transduction+++04744///Phototransduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0004984///olfactory receptor activity+++GO:0005524///ATP binding+++GO:0005549///odorant binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0016941///natriuretic peptide receptor activity GO:0003031///detection of carbon dioxide+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007608///sensory perception of smell+++GO:0008355///olfactory learning+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0042048///olfactory behavior+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 14919 14919 'Gucy2e' mRNA 13 18 12 0.09 0.12 0.09 0.05 0.01 0 0.1 0.02 9 2 0 14.33333333 3.666666667 0.057663584 -1.987094689 00230///Purine metabolism+++04740///Olfactory transduction+++04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007601///visual perception+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0019934///cGMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0050896///response to stimulus 14923 14923 'Guk1' mRNA 1649 1705 1597 111 112.89 112.95 91.92 95.54 95.41 112.28 94.29 1575 1607 1585 1650.333333 1589 0.470299787 -0.065645542 00230///Purine metabolism GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004385///guanylate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006163///purine nucleotide metabolic process+++GO:0006185///dGDP biosynthetic process+++GO:0006805///xenobiotic metabolic process+++GO:0016310///phosphorylation+++GO:0019673///GDP-mannose metabolic process+++GO:0034436///glycoprotein transport+++GO:0046034///ATP metabolic process+++GO:0046037///GMP metabolic process+++GO:0046054///dGMP metabolic process+++GO:0046060///dATP metabolic process+++GO:0046710///GDP metabolic process+++GO:0046711///GDP biosynthetic process+++GO:0046939///nucleotide phosphorylation 14924 14924 'Magi1' mRNA 1302 1266 1126 4.94 4.48 4.67 2.39 2.42 2.38 4.696666667 2.396666667 696.03 643 681 1231.333333 673.3433333 1.47E-23 -0.880972167 04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051393///alpha-actinin binding+++GO:0060090///molecular adaptor activity GO:0007165///signal transduction+++GO:0022409///positive regulation of cell-cell adhesion 14933 14933 'Gk' mRNA 612 559 589 8.7 7.61 8.72 11.51 9.41 10.11 8.343333333 10.34333333 962 751 793 586.6666667 835.3333333 2.36E-05 0.494714368 00561///Glycerolipid metabolism+++03320///PPAR signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0042393///histone binding" GO:0005975///carbohydrate metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0016310///phosphorylation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019563///glycerol catabolic process+++GO:0042593///glucose homeostasis+++GO:0045471///response to ethanol+++GO:0046167///glycerol-3-phosphate biosynthetic process 14934 14934 'Gypa' mRNA 3 3 0 0.09 0.09 0 0.16 0 0.03 0.06 0.063333333 6 0 1 2 2.333333333 0.93108396 0.219164856 04640///Hematopoietic cell lineage+++05144///Malaria GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0047484///regulation of response to osmotic stress 14936 14936 'Gys1' mRNA 1067.44 1004.94 1052.58 15.72 14.56 16.45 9.27 8.99 8.57 15.57666667 8.943333333 723.89 686.13 648.53 1041.653333 686.1833333 3.07E-10 -0.615955925 00500///Starch and sucrose metabolism+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0016234///inclusion body "GO:0003824///catalytic activity+++GO:0004373///glycogen (starch) synthase activity+++GO:0005515///protein binding+++GO:0005536///glucose binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019901///protein kinase binding+++GO:0061547///glycogen synthase activity, transferring glucose-1-phosphate" GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0007507///heart development+++GO:0008152///metabolic process 14938 14938 'Gzma' mRNA 12 9 11 0.9 0.67 0.88 4.39 5.25 5.29 0.816666667 4.976666667 67 78 78 10.66666667 74.33333333 6.70E-11 2.789928307 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005634///nucleus GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity GO:0006508///proteolysis+++GO:0009617///response to bacterium+++GO:0019835///cytolysis+++GO:0032078///negative regulation of endodeoxyribonuclease activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070269///pyroptosis+++GO:1902483///cytotoxic T cell apoptotic process 14939 14939 'Gzmb' mRNA 6 11 10 0.23 0.42 0.41 3.09 3.27 2.53 0.353333333 2.963333333 91 94 72 9 85.66666667 1.00E-13 3.238309498 04210///Apoptosis+++04650///Natural killer cell mediated cytotoxicity+++04940///Type I diabetes mellitus+++05202///Transcriptional misregulation in cancer+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044194///cytolytic granule GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001913///T cell mediated cytotoxicity+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0017148///negative regulation of translation+++GO:0019835///cytolysis+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070269///pyroptosis 14940 14940 'Gzmc' mRNA 7 6 2 0.49 0.41 0.15 0.06 0.37 0 0.35 0.143333333 1 6 0 5 2.333333333 0.541743127 -1.079385188 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044194///cytolytic granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0017148///negative regulation of translation+++GO:0019835///cytolysis+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070269///pyroptosis 14941 14941 'Gzmd' mRNA 0 2 1 0 0.14 0.07 0 0.06 0 0.07 0.02 0 1 0 1 0.333333333 0.727684624 -1.487414893 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044194///cytolytic granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0017148///negative regulation of translation+++GO:0019835///cytolysis+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070269///pyroptosis 14942 14942 'Gzme' mRNA 0 1 2 0 0.07 0.15 0.37 0.25 0.38 0.073333333 0.333333333 6 4 6 1 5.333333333 0.155966174 2.383143551 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044194///cytolytic granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0017148///negative regulation of translation+++GO:0019835///cytolysis+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070269///pyroptosis 14945 14945 'Gzmk' mRNA 0 0 2 0 0 0.12 0.64 0.51 1.43 0.04 0.86 13 10 28 0.666666667 17 7.35E-04 4.644438746 GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 14950 14950 'H13' mRNA 4130 4229 3887 104.83 105.52 108.63 136.56 144.35 141.71 106.3266667 140.8733333 5808 5953 5802 4082 5854.333333 3.67E-20 0.50978341 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane "GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0042803///protein homodimerization activity" "GO:0001701///in utero embryonic development+++GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0033619///membrane protein proteolysis+++GO:1904211///membrane protein proteolysis involved in retrograde protein transport, ER to cytosol" 14957 14957 'H1f3' mRNA 1.01 3.11 2.06 0.09 0.27 0.19 0.7 0.97 1.21 0.183333333 0.96 9.04 12.17 15.12 2.06 12.11 0.017656619 2.5780562 GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:0080182///histone H3-K4 trimethylation+++GO:0098532///histone H3-K27 trimethylation 14958 14958 'H1f0' mRNA 5590 5973 2808 136.88 144.03 72.94 52 86.49 78.66 117.95 72.38333333 2442 3966 3576 4790.333333 3328 0.204540131 -0.515896717 GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0015629///actin cytoskeleton+++GO:0016604///nuclear body+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0016458///gene silencing+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:2000679///positive regulation of transcription regulatory region DNA binding 14960 14960 'H2-Aa' mRNA 1039 1069 1114 57.29 58.24 65.17 110.5 117.21 112.06 60.23333333 113.2566667 2299 2378 2254 1074 2310.333333 2.38E-41 1.091910546 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042613///MHC class II protein complex GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding+++GO:0042605///peptide antigen binding+++GO:0044877///protein-containing complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0034341///response to interferon-gamma+++GO:0042130///negative regulation of T cell proliferation+++GO:0045582///positive regulation of T cell differentiation+++GO:0048002///antigen processing and presentation of peptide antigen+++GO:0050870///positive regulation of T cell activation 14961 14961 'H2-Ab1' mRNA 1655 1779 1636 85.3 90.56 89.46 175.47 188.77 174.51 88.44 179.5833333 3907 4099 3757 1690 3921 6.22E-70 1.203494243 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005622///intracellular+++GO:0005769///early endosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042613///MHC class II protein complex GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0015643///toxic substance binding+++GO:0023026///MHC class II protein complex binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042605///peptide antigen binding+++GO:0044877///protein-containing complex binding+++GO:1990405///protein antigen binding GO:0002250///adaptive immune response+++GO:0002344///B cell affinity maturation+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002579///positive regulation of antigen processing and presentation+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0042130///negative regulation of T cell proliferation+++GO:0046635///positive regulation of alpha-beta T cell activation+++GO:0048002///antigen processing and presentation of peptide antigen+++GO:0050852///T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0071346///cellular response to interferon-gamma 14962 14962 'Cfb' mRNA 165 208 211 3.32 4.12 4.5 38.64 39.57 38.05 3.98 38.75333333 2209 2209 2106 194.6666667 2174.666667 2.55E-236 3.468753853 04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0008283///cell proliferation+++GO:0045087///innate immune response+++GO:0097066///response to thyroid hormone" 14964 14964 'H2-D1' mRNA 26805.01 27639.54 26902.07 893.99 908.64 951.85 2237.45 2302.39 2194.15 918.16 2244.663333 77097.96 77432.85 73162.19 27115.54 75897.66667 8.81E-185 1.472621858 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0045121///membrane raft+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002485///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006952///defense response+++GO:0006955///immune response+++GO:0010977///negative regulation of neuron projection development+++GO:0019882///antigen processing and presentation" 14969 14969 'H2-Eb1' mRNA 327 298 313 11.4 10.24 11.58 33.26 34.11 35.66 11.07333333 34.34333333 1096 1097 1137 312.6666667 1110 2.11E-67 1.815803726 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0001772///immunological synapse+++GO:0005765///lysosomal membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0042613///MHC class II protein complex GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding+++GO:0030247///polysaccharide binding+++GO:0032395///MHC class II receptor activity+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042609///CD4 receptor binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0034341///response to interferon-gamma+++GO:0050870///positive regulation of T cell activation 14972 14972 'H2-K1' mRNA 9470.42 9463.21 9069.79 329.4 325.22 335.06 710.67 712.62 718.28 329.8933333 713.8566667 23286.31 22797.88 22788.26 9334.473333 22957.48333 1.43E-169 1.28666895 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002485///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0010977///negative regulation of neuron projection development+++GO:0019882///antigen processing and presentation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0042742///defense response to bacterium+++GO:0048839///inner ear development" 14976 14976 'Pfdn6' mRNA 658 684 659 64.73 67.5 68.8 68.74 73.2 66.16 67.01 69.36666667 799 828 742 667 789.6666667 0.034356655 0.231901202 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016272///prefoldin complex GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly+++GO:1905907///negative regulation of amyloid fibril formation 14977 14977 'Slc39a7' mRNA 4853 4807 4901 117.23 114.97 126.2 159.3 153.08 159.59 119.4666667 157.3233333 7508 7084 7269 4853.666667 7287 1.51E-22 0.572770792 05010///Alzheimer disease+++05012///Parkinson disease GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport 14979 14979 'H2-Ke6' mRNA 1097 1164 293 73.43 77.08 20.81 17.17 36.31 34.75 57.10666667 29.41 294 606 575 851.3333333 491.6666667 0.314575933 -0.770339339 00061///Fatty acid biosynthesis+++00140///Steroid hormone biosynthesis+++01212///Fatty acid metabolism GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:1990204///oxidoreductase complex "GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0047025///3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0048038///quinone binding+++GO:0070404///NADH binding+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006694///steroid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0051290///protein heterotetramerization 14991 14991 'H2-M3' mRNA 176 139 146 7.19 5.59 6.32 24.16 25.89 24.29 6.366666667 24.78 673 704.99 650.67 153.6666667 676.22 3.39E-53 2.125678344 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002237///response to molecule of bacterial origin+++GO:0002287///alpha-beta T cell activation involved in immune response+++GO:0002451///peripheral B cell tolerance induction+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002477///antigen processing and presentation of exogenous peptide antigen via MHC class Ib+++GO:0002481///antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0002645///positive regulation of tolerance induction+++GO:0002666///positive regulation of T cell tolerance induction+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002767///immune response-inhibiting cell surface receptor signaling pathway+++GO:0006955///immune response+++GO:0016525///negative regulation of angiogenesis+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0070207///protein homotrimerization+++GO:0070317///negative regulation of G0 to G1 transition+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000774///positive regulation of cellular senescence+++GO:2001199///negative regulation of dendritic cell differentiation" 14997 14997 'H2-M9' mRNA 4 0 1 0.22 0 0.04 0 0 0 0.086666667 0 0 0 0 1.666666667 0 0.380997697 -3.185375956 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 14998 14998 'H2-DMa' mRNA 913.52 934.87 902.35 27.8 27.54 28.92 36.55 39.38 37.6 28.08666667 37.84333333 1331.9 1384.3 1313.74 916.9133333 1343.313333 2.57E-10 0.539740776 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0042613///MHC class II protein complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002636///positive regulation of germinal center formation+++GO:0002922///positive regulation of humoral immune response+++GO:0006955///immune response+++GO:0015031///protein transport+++GO:0016064///immunoglobulin mediated immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0045059///positive thymic T cell selection+++GO:0045582///positive regulation of T cell differentiation+++GO:0048839///inner ear development+++GO:0050778///positive regulation of immune response+++GO:0050870///positive regulation of T cell activation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0065003///protein-containing complex assembly 14999 14999 'H2-DMb1' mRNA 420.11 420.89 580.54 19.84 19.62 29.09 24.8 29.14 28.76 22.85 27.56666667 602.92 690.9 676.08 473.8466667 656.6333333 0.005251004 0.45174806 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0042613///MHC class II protein complex+++GO:0043231///intracellular membrane-bounded organelle GO:0023026///MHC class II protein complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002399///MHC class II protein complex assembly+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0042102///positive regulation of T cell proliferation+++GO:0050870///positive regulation of T cell activation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:2001190///positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 15000 15000 'H2-DMb2' mRNA 244.85 237.84 253.68 10.35 9.92 11.38 15.2 12.89 13.19 10.55 13.76 412.89 341.64 346.59 245.4566667 367.04 2.34E-04 0.56729085 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0042613///MHC class II protein complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002399///MHC class II protein complex assembly+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0042102///positive regulation of T cell proliferation+++GO:0050870///positive regulation of T cell activation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:2001190///positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 15001 15001 'H2-Oa' mRNA 8 4 9 0.47 0.23 0.58 1.1 1.24 1.25 0.426666667 1.196666667 21 23 23 7 22.33333333 0.018189333 1.654878202 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042613///MHC class II protein complex GO:0023026///MHC class II protein complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002587///negative regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0045580///regulation of T cell differentiation+++GO:0050870///positive regulation of T cell activation 15002 15002 'H2-Ob' mRNA 7 11 2 0.15 0.22 0.04 0.49 0.24 0.3 0.136666667 0.343333333 27 13 16 6.666666667 18.66666667 0.06998321 1.486508443 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042613///MHC class II protein complex GO:0023026///MHC class II protein complex binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002587///negative regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050870///positive regulation of T cell activation 15006 15006 'H2-Q1' mRNA 313.65 290.38 249.17 12.76 11.59 10.63 22.89 19.42 20.02 11.66 20.77666667 638.63 550.44 544.68 284.4 577.9166667 4.56E-15 1.013317404 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation" 15007 15007 'H2-Q10' mRNA 26.84 27.13 18.79 1.08 1.08 0.8 4.89 4.86 4.58 0.986666667 4.776666667 139.52 135.39 126.37 24.25333333 133.76 2.61E-16 2.486830602 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 15013 15013 'H2-Q2' mRNA 139.53 124.12 125.62 3.97 3.47 3.77 8.42 9.38 9.2 3.736666667 9 339.95 371.01 359.47 129.7566667 356.81 1.17E-18 1.451608234 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0007565///female pregnancy+++GO:0019882///antigen processing and presentation+++GO:0035264///multicellular organism growth" 15015 15015 'H2-Q4' mRNA 362.92 373.87 312.69 11.67 11.85 10.67 19.48 18.72 21.47 11.39666667 19.89 696.33 653.08 742.44 349.8266667 697.2833333 1.64E-17 0.988685131 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0045121///membrane raft+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002485///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0010977///negative regulation of neuron projection development+++GO:0019882///antigen processing and presentation" 15018 15018 'H2-Q7' mRNA 57.07 53.59 68.86 2.59 2.34 3.47 15.55 18.48 23.23 2.8 19.08666667 379.27 424.64 533.08 59.84 445.6633333 7.60E-46 2.89459817 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042277///peptide binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response+++GO:0007566///embryo implantation+++GO:0071346///cellular response to interferon-gamma" 15039 15039 'H2-T22' mRNA 778.28 827.53 770.63 18.9 19.4 19.38 63.37 60.79 58.69 19.22666667 60.95 2437.74 2315.81 2185.09 792.1466667 2312.88 8.91E-88 1.534599616 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 15040 15040 'H2-T23' mRNA 4541.55 4306.68 4702.9 208.15 194.83 228.69 394.87 374.01 380.57 210.5566667 383.15 9891.5 9139.11 9220.11 4517.043333 9416.906667 1.22E-55 1.044921103 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001815///positive regulation of antibody-dependent cellular cytotoxicity+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002477///antigen processing and presentation of exogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0002489///antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent+++GO:0002519///natural killer cell tolerance induction+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002715///regulation of natural killer cell mediated immunity+++GO:0002717///positive regulation of natural killer cell mediated immunity+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0019731///antibacterial humoral response+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032759///positive regulation of TRAIL production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0048839///inner ear development+++GO:0050830///defense response to Gram-positive bacterium+++GO:2000566///positive regulation of CD8-positive, alpha-beta T cell proliferation+++GO:2001187///positive regulation of CD8-positive, alpha-beta T cell activation" 15042 15042 'H2-T24' mRNA 562 512.52 499.77 14.53 13.05 13.71 23.64 21.27 24.33 13.76333333 23.08 1051.1 923.34 1047.31 524.7633333 1007.25 3.13E-20 0.929587348 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0042605///peptide antigen binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 15043 15043 'H2-T3' mRNA 0 3 3 0 0.08 0.08 0.02 0 0 0.053333333 0.006666667 1 0 0 2 0.333333333 0.40914753 -2.506306225 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex+++GO:0042824///MHC class I peptide loading complex+++GO:0070971///endoplasmic reticulum exit site+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046977///TAP binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0051087///chaperone binding+++GO:0062061///TAP complex binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 15064 15064 'Mr1' mRNA 515 530 552 11.38 11.54 13.02 14.06 12.81 13.76 11.98 13.54333333 729 648 687 532.3333333 688 0.002048507 0.355746431 GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0042612///MHC class I protein complex GO:0030881///beta-2-microglobulin binding+++GO:0042608///T cell receptor binding GO:0002367///cytokine production involved in immune response+++GO:0002376///immune system process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0002854///positive regulation of T cell mediated cytotoxicity directed against tumor cell target+++GO:0006955///immune response+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:0032611///interleukin-1 beta production+++GO:0032620///interleukin-17 production+++GO:0033077///T cell differentiation in thymus+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 15078 15078 'H3f3a' mRNA 11742.61 11725.58 11443.9 678.1 669.19 701.18 843.49 811.38 848.6 682.8233333 834.49 16754.51 15713.03 16293.74 11637.36333 16253.76 2.14E-21 0.469491592 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0000786///nucleosome+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex" GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity GO:0001649///osteoblast differentiation+++GO:0006334///nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006997///nucleus organization+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007338///single fertilization+++GO:0007566///embryo implantation+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0030307///positive regulation of cell growth+++GO:0031508///pericentric heterochromatin assembly+++GO:0031509///telomeric heterochromatin assembly+++GO:0035264///multicellular organism growth+++GO:0042692///muscle cell differentiation+++GO:0048477///oogenesis+++GO:0090230///regulation of centromere complex assembly+++GO:1902340///negative regulation of chromosome condensation 15081 15081 'H3f3b' mRNA 18634.52 19595.5 18636.49 527.84 547.49 560.41 585.32 593.59 577.25 545.2466667 585.3866667 23762 23565.94 22723 18955.50333 23350.31333 1.67E-08 0.288876702 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0032991///protein-containing complex" GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity GO:0001649///osteoblast differentiation+++GO:0006334///nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006997///nucleus organization+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007338///single fertilization+++GO:0007420///brain development+++GO:0007566///embryo implantation+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0009725///response to hormone+++GO:0030307///positive regulation of cell growth+++GO:0031508///pericentric heterochromatin assembly+++GO:0031509///telomeric heterochromatin assembly+++GO:0035264///multicellular organism growth+++GO:0042692///muscle cell differentiation+++GO:0048477///oogenesis+++GO:0090230///regulation of centromere complex assembly+++GO:1902340///negative regulation of chromosome condensation 15107 15107 'Hadh' mRNA 1808 1798 1646 58.29 57.13 56.3 51.7 54.84 52.64 57.24 53.06 1843 1908 1816 1750.666667 1855.666667 0.393062992 0.073922103 "00062///Fatty acid elongation+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00650///Butanoate metabolism+++01212///Fatty acid metabolism" GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0070403///NAD+ binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0014823///response to activity+++GO:0032868///response to insulin+++GO:0042493///response to drug+++GO:0046676///negative regulation of insulin secretion+++GO:0050796///regulation of insulin secretion+++GO:0120162///positive regulation of cold-induced thermogenesis 15108 15108 'Hsd17b10' mRNA 1307 1424 1335 93.98 101.35 101.86 100.67 103.51 104.46 99.06333333 102.88 1604 1607 1608 1355.333333 1606.333333 0.0042593 0.233564652 "00280///Valine, leucine and isoleucine degradation+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0030678///mitochondrial ribonuclease P complex+++GO:0042645///mitochondrial nucleoid "GO:0000049///tRNA binding+++GO:0001540///amyloid-beta binding+++GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0005496///steroid binding+++GO:0008709///cholate 7-alpha-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0018454///acetoacetyl-CoA reductase activity+++GO:0030283///testosterone dehydrogenase [NAD(P)] activity+++GO:0030331///estrogen receptor binding+++GO:0042802///identical protein binding+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0047015///3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity+++GO:0051287///NAD binding" GO:0006550///isoleucine catabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006699///bile acid biosynthetic process+++GO:0007005///mitochondrion organization+++GO:0008033///tRNA processing+++GO:0008202///steroid metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0051289///protein homotetramerization+++GO:0070901///mitochondrial tRNA methylation+++GO:0097745///mitochondrial tRNA 5'-end processing+++GO:1990180///mitochondrial tRNA 3'-end processing 15109 15109 'Hal' mRNA 9 10 7 0.18 0.2 0.15 20.55 20.46 23.48 0.176666667 21.49666667 1188 1155 1314 8.666666667 1219 7.89E-122 7.125968339 00340///Histidine metabolism GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004397///histidine ammonia-lyase activity+++GO:0016829///lyase activity+++GO:0016841///ammonia-lyase activity GO:0006547///histidine metabolic process+++GO:0006548///histidine catabolic process+++GO:0019556///histidine catabolic process to glutamate and formamide+++GO:0019557///histidine catabolic process to glutamate and formate 15112 15112 'Hao1' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++04146///Peroxisome GO:0005777///peroxisome GO:0003824///catalytic activity+++GO:0003973///(S)-2-hydroxy-acid oxidase activity+++GO:0008891///glycolate oxidase activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0052852///very-long-chain-(S)-2-hydroxy-acid oxidase activity+++GO:0052853///long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity+++GO:0052854///medium-chain-(S)-2-hydroxy-acid oxidase activity GO:0001561///fatty acid alpha-oxidation+++GO:0006979///response to oxidative stress+++GO:0046296///glycolate catabolic process 15114 15114 'Hap1' mRNA 1192 1287 1129 18.62 19.71 18.53 12.75 12.42 12.66 18.95333333 12.61 950 897 919 1202.666667 922 4.06E-06 -0.393942318 04727///GABAergic synapse+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0016234///inclusion body+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098982///GABA-ergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol+++GO:1904115///axon cytoplasm GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0048403///brain-derived neurotrophic factor binding "GO:0006605///protein targeting+++GO:0006887///exocytosis+++GO:0006914///autophagy+++GO:0008089///anterograde axonal transport+++GO:0008090///retrograde axonal transport+++GO:0008104///protein localization+++GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0021549///cerebellum development+++GO:0021979///hypothalamus cell differentiation+++GO:0022008///neurogenesis+++GO:0030030///cell projection organization+++GO:0031175///neuron projection development+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032901///positive regulation of neurotrophin production+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0047496///vesicle transport along microtubule+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048311///mitochondrion distribution+++GO:0050769///positive regulation of neurogenesis+++GO:0090261///positive regulation of inclusion body assembly+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902513///regulation of organelle transport along microtubule+++GO:1902857///positive regulation of non-motile cilium assembly" 15115 15115 'Hars' mRNA 1376 1546 1337 39.41 43.62 40.62 44.27 43.05 44.94 41.21666667 44.08666667 1777 1687 1746 1419.666667 1736.666667 3.49E-04 0.280311051 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004821///histidine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006427///histidyl-tRNA aminoacylation+++GO:0032543///mitochondrial translation 15116 15116 'Has1' mRNA 17 13 13 0.46 0.35 0.37 0.71 0.7 0.71 0.393333333 0.706666667 30 29 29 14.33333333 29.33333333 0.067055853 1.022693027 GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042802///identical protein binding+++GO:0050501///hyaluronan synthase activity" GO:0010764///negative regulation of fibroblast migration+++GO:0030213///hyaluronan biosynthetic process+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0044849///estrous cycle+++GO:0045226///extracellular polysaccharide biosynthetic process+++GO:0085029///extracellular matrix assembly 15118 15118 'Has3' mRNA 28 35 21 0.25 0.32 0.27 0.14 0.1 0.22 0.28 0.153333333 15 12 25 28 17.33333333 0.254146007 -0.695410814 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036117///hyaluranon cable "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042802///identical protein binding+++GO:0050501///hyaluronan synthase activity" "GO:0030213///hyaluronan biosynthetic process+++GO:0045226///extracellular polysaccharide biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0085029///extracellular matrix assembly+++GO:1900106///positive regulation of hyaluranon cable assembly" 15122 15122 'Hba-a1' mRNA 2421.31 2357.34 2581.09 343.52 333.56 388.75 583.13 715.09 621.91 355.2766667 640.0433333 4683.41 5578.26 4810.45 2453.246667 5024.04 2.39E-31 1.021197227 05143///African trypanosomiasis+++05144///Malaria GO:0005615///extracellular space+++GO:0005833///hemoglobin complex+++GO:0022627///cytosolic small ribosomal subunit+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0005506///iron ion binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0031720///haptoglobin binding+++GO:0043177///organic acid binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0009617///response to bacterium+++GO:0010942///positive regulation of cell death+++GO:0015671///oxygen transport+++GO:0035634///response to stilbenoid+++GO:0042542///response to hydrogen peroxide+++GO:0042744///hydrogen peroxide catabolic process+++GO:0048821///erythrocyte development+++GO:0098869///cellular oxidant detoxification 15139 15139 'Hc' mRNA 68 84 85 0.67 0.81 0.89 0.28 0.35 0.38 0.79 0.336666667 33 40 43 79 38.66666667 0.002041837 -1.043520054 04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04936///Alcoholic liver disease+++05020///Prion disease+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005615///extracellular space GO:0004866///endopeptidase inhibitor activity "GO:0001701///in utero embryonic development+++GO:0001780///neutrophil homeostasis+++GO:0001822///kidney development+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019835///cytolysis+++GO:0032722///positive regulation of chemokine production+++GO:0032835///glomerulus development+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0090594///inflammatory response to wounding+++GO:0097273///creatinine homeostasis" 15159 15159 'Hccs' mRNA 579 647 362 12.95 14.36 8.72 9.5 14.75 13.04 12.01 12.43 477 736 644 529.3333333 619 0.275443568 0.22964291 00860///Porphyrin metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0004408///holocytochrome-c synthase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0018063///cytochrome c-heme linkage 15160 15160 'Serpind1' mRNA 79 90 68 2.17 2.41 1.93 0.93 0.86 0.94 2.17 0.91 39 35 39 79 37.66666667 0.00108816 -1.076629835 04610///Complement and coagulation cascades GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008201///heparin binding+++GO:0030414///peptidase inhibitor activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 15161 15161 'Hcfc1' mRNA 2466 2379 2132 14.45 13.44 13.36 12.16 11.15 12.84 13.75 12.05 2338 2118 2410 2325.666667 2288.666667 0.740165623 -0.033405021 04212///Longevity regulating pathway - worm+++05168///Herpes simplex virus 1 infection GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0035097///histone methyltransferase complex+++GO:0043025///neuronal cell body+++GO:0048188///Set1C/COMPASS complex+++GO:0062023///collagen-containing extracellular matrix+++GO:0070461///SAGA-type complex+++GO:0071339///MLL1 complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0033613///activating transcription factor binding+++GO:0042802///identical protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0010628///positive regulation of gene expression+++GO:0019046///release from viral latency+++GO:0043254///regulation of protein complex assembly+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0071407///cellular response to organic cyclic compound" 15162 15162 'Hck' mRNA 70 82 85 1.9 2.19 2.44 21.15 22.78 22.56 2.176666667 22.16333333 898 944 927 79 923 3.78E-132 3.534595606 04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006887///exocytosis+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0046777///protein autophosphorylation+++GO:0050764///regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0071801///regulation of podosome assembly+++GO:2000251///positive regulation of actin cytoskeleton reorganization 15163 15163 'Hcls1' mRNA 111 71 91 3.13 1.97 2.72 27.34 25.46 29.51 2.606666667 27.43666667 1115 1014 1165 91 1098 8.62E-135 3.580055988 04530///Tight junction+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0030427///site of polarized growth+++GO:0030864///cortical actin cytoskeleton GO:0001085///RNA polymerase II transcription factor binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030041///actin filament polymerization+++GO:0030218///erythrocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071345///cellular response to cytokine stimulus+++GO:2000107///negative regulation of leukocyte apoptotic process 15165 15165 'Hcn1' mRNA 916 788 572 6.09 5.15 4.04 0.7 0.43 0.79 5.093333333 0.64 121 73 132 758.6666667 108.6666667 2.38E-51 -2.809853632 04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0036477///somatodendritic compartment+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0097440///apical dendrite+++GO:0098855///HCN channel complex "GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0022843///voltage-gated cation channel activity+++GO:0030552///cAMP binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding" GO:0003254///regulation of membrane depolarization+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0045176///apical protein localization+++GO:0045759///negative regulation of action potential+++GO:0046549///retinal cone cell development+++GO:0051289///protein homotetramerization+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071805///potassium ion transmembrane transport+++GO:1902630///regulation of membrane hyperpolarization+++GO:2001259///positive regulation of cation channel activity 15166 15166 'Hcn2' mRNA 50 39 1 0.86 0.66 0.02 0.01 0.11 0.17 0.513333333 0.096666667 1 7 11 30 6.333333333 0.024291622 -2.211073495 04024///cAMP signaling pathway+++04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032590///dendrite membrane+++GO:0036477///somatodendritic compartment+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0098855///HCN channel complex GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0030552///cAMP binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071321///cellular response to cGMP+++GO:0071805///potassium ion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1990573///potassium ion import across plasma membrane 15168 15168 'Hcn3' mRNA 90 90 75 1.61 1.65 1.46 0.21 0.31 0.28 1.573333333 0.266666667 14 17 20 85 17 3.59E-10 -2.329219058 04929///GnRH secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0044316///cone cell pedicle+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0030552///cAMP binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0072718///response to cisplatin+++GO:1903351///cellular response to dopamine 15170 15170 'Ptpn6' mRNA 703 748 750 17.83 18.69 20.18 57.59 56.74 54.45 18.9 56.26 2609 2510 2388 733.6666667 2502.333333 6.83E-107 1.756965088 04520///Adherens junction+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05140///Leishmaniasis+++05205///Proteoglycans in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0032991///protein-containing complex+++GO:0042105///alpha-beta T cell receptor complex GO:0001784///phosphotyrosine residue binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0140031///phosphorylation-dependent protein binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002924///negative regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006470///protein dephosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016311///dephosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0030220///platelet formation+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033277///abortive mitotic cell cycle+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035855///megakaryocyte development+++GO:0042130///negative regulation of T cell proliferation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0045577///regulation of B cell differentiation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050853///B cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070527///platelet aggregation+++GO:1905867///epididymis development+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 15171 15171 'Hcrt' mRNA 0 0 3 0 0 0.42 0 0.12 0 0.14 0.04 0 1 0 1 0.333333333 0.733907355 -1.562034279 04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0005184///neuropeptide hormone activity+++GO:0031771///type 1 hypocretin receptor binding+++GO:0031772///type 2 hypocretin receptor binding GO:0001659///temperature homeostasis+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007631///feeding behavior+++GO:0008156///negative regulation of DNA replication+++GO:0030431///sleep+++GO:0042594///response to starvation+++GO:0042755///eating behavior+++GO:0043267///negative regulation of potassium ion transport+++GO:0046928///regulation of neurotransmitter secretion+++GO:0051928///positive regulation of calcium ion transport+++GO:0051970///negative regulation of transmission of nerve impulse+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0060079///excitatory postsynaptic potential+++GO:0120162///positive regulation of cold-induced thermogenesis 15182 15182 'Hdac2' mRNA 811 805 368 23.03 22.47 11.08 11.65 11.3 12.33 18.86 11.76 472 447 482 661.3333333 467 0.187894829 -0.497129596 04110///Cell cycle+++04213///Longevity regulating pathway - multiple species+++04330///Notch signaling pathway+++04613///Neutrophil extracellular trap formation+++04919///Thyroid hormone signaling pathway+++05016///Huntington disease+++05031///Amphetamine addiction+++05034///Alcoholism+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05220///Chronic myeloid leukemia GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016580///Sin3 complex+++GO:0016581///NuRD complex+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0035098///ESC/E(Z) complex+++GO:0090571///RNA polymerase II transcription repressor complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001222///transcription corepressor binding+++GO:0003682///chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031490///chromatin DNA binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0034739///histone deacetylase activity (H4-K16 specific)+++GO:0035851///Krueppel-associated box domain binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001975///response to amphetamine+++GO:0003300///cardiac muscle hypertrophy+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0008284///positive regulation of cell proliferation+++GO:0009913///epidermal cell differentiation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010977///negative regulation of neuron projection development+++GO:0016358///dendrite development+++GO:0016575///histone deacetylation+++GO:0021766///hippocampus development+++GO:0030182///neuron differentiation+++GO:0031000///response to caffeine+++GO:0032496///response to lipopolysaccharide+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032922///circadian regulation of gene expression+++GO:0034605///cellular response to heat+++GO:0035094///response to nicotine+++GO:0035984///cellular response to trichostatin A+++GO:0042220///response to cocaine+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045862///positive regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048149///behavioral response to ethanol+++GO:0048511///rhythmic process+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051896///regulation of protein kinase B signaling+++GO:0055013///cardiac muscle cell development+++GO:0055093///response to hyperoxia+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060297///regulation of sarcomere organization+++GO:0060789///hair follicle placode formation+++GO:0061000///negative regulation of dendritic spine development+++GO:0061029///eyelid development in camera-type eye+++GO:0061198///fungiform papilla formation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070734///histone H3-K27 methylation+++GO:0070829///heterochromatin maintenance+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071300///cellular response to retinoic acid+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090311///regulation of protein deacetylation+++GO:1902437///positive regulation of male mating behavior+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903351///cellular response to dopamine+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000757///negative regulation of peptidyl-lysine acetylation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 15183 15183 'Hdac3' mRNA 5031 4950 4523 142.82 138.44 136.21 95.98 92.27 91.64 139.1566667 93.29666667 3887 3648 3592 4834.666667 3709 3.79E-12 -0.393254255 04613///Neutrophil extracellular trap formation+++04919///Thyroid hormone signaling pathway+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0017053///transcriptional repressor complex+++GO:0072686///mitotic spindle GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0019899///enzyme binding+++GO:0030332///cyclin binding+++GO:0031490///chromatin DNA binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding+++GO:0051059///NF-kappaB binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0007346///regulation of mitotic cell cycle+++GO:0016575///histone deacetylation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032008///positive regulation of TOR signaling+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032922///circadian regulation of gene expression+++GO:0040014///regulation of multicellular organism growth+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042752///regulation of circadian rhythm+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0046826///negative regulation of protein export from nucleus+++GO:0048511///rhythmic process+++GO:0051225///spindle assembly+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071498///cellular response to fluid shear stress+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1990679///histone H4-K12 deacetylation+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process+++GO:2000726///negative regulation of cardiac muscle cell differentiation" 15184 15184 'Hdac5' mRNA 1991 1997 1792 28.3 28.07 27.13 17.03 16.86 16.64 27.83333333 16.84333333 1371 1319 1303 1926.666667 1331 2.57E-14 -0.543967389 04371///Apelin signaling pathway+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0044295///axonal growth cone+++GO:0090571///RNA polymerase II transcription repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002076///osteoblast development+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0006954///inflammatory response+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0010629///negative regulation of gene expression+++GO:0010830///regulation of myotube differentiation+++GO:0010832///negative regulation of myotube differentiation+++GO:0014823///response to activity+++GO:0016575///histone deacetylation+++GO:0030182///neuron differentiation+++GO:0030183///B cell differentiation+++GO:0033555///multicellular organismal response to stress+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042113///B cell activation+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0061333///renal tubule morphogenesis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071498///cellular response to fluid shear stress+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000648///positive regulation of stem cell proliferation" 15185 15185 'Hdac6' mRNA 611 592 590 8.32 7.93 8.63 7.74 7 7.03 8.293333333 7.256666667 649 576 572 597.6666667 599 0.948628687 -0.009865858 04613///Neutrophil extracellular trap formation+++05014///Amyotrophic lateral sclerosis+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016234///inclusion body+++GO:0016235///aggresome+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0017053///transcriptional repressor complex+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030286///dynein complex+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0031594///neuromuscular junction+++GO:0031672///A band+++GO:0032991///protein-containing complex+++GO:0042641///actomyosin+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0090571///RNA polymerase II transcription repressor complex+++GO:1904115///axon cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003779///actin binding+++GO:0004407///histone deacetylase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008017///microtubule binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019789///SUMO transferase activity+++GO:0019901///protein kinase binding+++GO:0030955///potassium ion binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0042903///tubulin deacetylase activity+++GO:0043014///alpha-tubulin binding+++GO:0043130///ubiquitin binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0047611///acetylspermidine deacetylase activity+++GO:0048156///tau protein binding+++GO:0048487///beta-tubulin binding+++GO:0051787///misfolded protein binding+++GO:0051879///Hsp90 protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070840///dynein complex binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0001501///skeletal system development+++GO:0002076///osteoblast development+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006476///protein deacetylation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006886///intracellular protein transport+++GO:0006954///inflammatory response+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010629///negative regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010830///regulation of myotube differentiation+++GO:0010832///negative regulation of myotube differentiation+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0014823///response to activity+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0014902///myotube differentiation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016241///regulation of macroautophagy+++GO:0016575///histone deacetylation+++GO:0016925///protein sumoylation+++GO:0019896///axonal transport of mitochondrion+++GO:0030182///neuron differentiation+++GO:0030183///B cell differentiation+++GO:0031333///negative regulation of protein complex assembly+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032418///lysosome localization+++GO:0032984///protein-containing complex disassembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0033555///multicellular organismal response to stress+++GO:0034983///peptidyl-lysine deacetylation+++GO:0035967///cellular response to topologically incorrect protein+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042113///B cell activation+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0043242///negative regulation of protein complex disassembly+++GO:0043393///regulation of protein binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045598///regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045820///negative regulation of glycolytic process+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045861///negative regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048668///collateral sprouting+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0051646///mitochondrion localization+++GO:0051788///response to misfolded protein+++GO:0060997///dendritic spine morphogenesis+++GO:0061333///renal tubule morphogenesis+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0070201///regulation of establishment of protein localization+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070555///response to interleukin-1+++GO:0070842///aggresome assembly+++GO:0070845///polyubiquitinated misfolded protein transport+++GO:0070846///Hsp90 deacetylation+++GO:0070848///response to growth factor+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071218///cellular response to misfolded protein+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0071498///cellular response to fluid shear stress+++GO:0090042///tubulin deacetylation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0106047///polyamine deacetylation+++GO:0106048///spermidine deacetylation+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:1902437///positive regulation of male mating behavior+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000648///positive regulation of stem cell proliferation" 15186 15186 'Hdc' mRNA 54 54 35 1.26 1.24 0.86 0.89 0.95 0.94 1.12 0.926666667 44 46 45 47.66666667 45 0.863090843 -0.086790091 00340///Histidine metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003824///catalytic activity+++GO:0004398///histidine decarboxylase activity+++GO:0016597///amino acid binding+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding GO:0001692///histamine metabolic process+++GO:0001694///histamine biosynthetic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006547///histidine metabolic process+++GO:0006548///histidine catabolic process+++GO:0019752///carboxylic acid metabolic process+++GO:0042423///catecholamine biosynthetic process 15191 15191 'Hdgf' mRNA 1711 1636 1593 43.13 40.54 42.47 42.71 47.35 48.29 42.04666667 46.11666667 1952 2111 2136 1646.666667 2066.333333 7.38E-05 0.316929156 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex "GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0015631///tubulin binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0009987///cellular process+++GO:0034504///protein localization to nucleus+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051781///positive regulation of cell division+++GO:0098761///cellular response to interleukin-7 15193 15193 'Hdgfl2' mRNA 1506 1472 1500 36.54 35.24 38.83 28.36 28.99 26.19 36.87 27.84666667 1339 1333 1197 1492.666667 1289.666667 0.012817818 -0.223836291 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030307///positive regulation of cell growth 15194 15194 'Htt' mRNA 767 807 695 3.81 3.84 3.51 3.89 3.68 4.25 3.72 3.94 903 802 943 756.3333333 882.6666667 0.046748926 0.212604295 05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016234///inclusion body+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0002039///p53 binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0008134///transcription factor binding+++GO:0019900///kinase binding+++GO:0031072///heat shock protein binding+++GO:0034452///dynactin binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0045505///dynein intermediate chain binding+++GO:0048487///beta-tubulin binding+++GO:0050809///diazepam binding "GO:0000050///urea cycle+++GO:0000052///citrulline metabolic process+++GO:0000132///establishment of mitotic spindle orientation+++GO:0006839///mitochondrial transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007005///mitochondrion organization+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007212///dopamine receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007369///gastrulation+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007569///cell aging+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0008088///axo-dendritic transport+++GO:0008306///associative learning+++GO:0008340///determination of adult lifespan+++GO:0008542///visual learning+++GO:0009653///anatomical structure morphogenesis+++GO:0009790///embryo development+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0016197///endosomal transport+++GO:0019244///lactate biosynthetic process from pyruvate+++GO:0019805///quinolinate biosynthetic process+++GO:0021756///striatum development+++GO:0021988///olfactory lobe development+++GO:0021990///neural plate formation+++GO:0022008///neurogenesis+++GO:0030072///peptide hormone secretion+++GO:0030073///insulin secretion+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0031648///protein destabilization+++GO:0034504///protein localization to nucleus+++GO:0035176///social behavior+++GO:0042297///vocal learning+++GO:0042445///hormone metabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0045724///positive regulation of cilium assembly+++GO:0047496///vesicle transport along microtubule+++GO:0048167///regulation of synaptic plasticity+++GO:0048341///paraxial mesoderm formation+++GO:0048666///neuron development+++GO:0051028///mRNA transport+++GO:0051592///response to calcium ion+++GO:0055072///iron ion homeostasis+++GO:0071539///protein localization to centrosome+++GO:0099111///microtubule-based transport+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1900180///regulation of protein localization to nucleus+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:1904504///positive regulation of lipophagy+++GO:1904580///regulation of intracellular mRNA localization+++GO:1905289///regulation of CAMKK-AMPK signaling cascade+++GO:1905337///positive regulation of aggrephagy+++GO:1905505///positive regulation of motile cilium assembly+++GO:2000117///negative regulation of cysteine-type endopeptidase activity+++GO:2000479///regulation of cAMP-dependent protein kinase activity+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 15199 15199 'Hebp1' mRNA 155 146 134 9.21 8.58 8.45 25.49 22.69 28.28 8.746666667 25.48666667 492 427 528 145 482.3333333 7.30E-30 1.723026452 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0020037///heme binding GO:0042168///heme metabolic process 15200 15200 'Hbegf' mRNA 367 382 359 8.65 8.86 8.97 15.51 13.7 14.52 8.826666667 14.57666667 757 653 686 369.3333333 698.6666667 1.09E-15 0.907197597 "01522///Endocrine resistance+++04012///ErbB signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05219///Bladder cancer" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005154///epidermal growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding "GO:0001525///angiogenesis+++GO:0001832///blastocyst growth+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008016///regulation of heart contraction+++GO:0008284///positive regulation of cell proliferation+++GO:0016477///cell migration+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051545///negative regulation of elastin biosynthetic process+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0090303///positive regulation of wound healing" 15201 15201 'Hells' mRNA 66.02 84.86 86.77 0.62 0.7 0.8 2.92 2.22 2.53 0.706666667 2.556666667 241.28 182.57 206.41 79.21666667 210.0866667 3.67E-10 1.39788804 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin" GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0001655///urogenital system development+++GO:0006306///DNA methylation+++GO:0006342///chromatin silencing+++GO:0006346///methylation-dependent chromatin silencing+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0010216///maintenance of DNA methylation+++GO:0030098///lymphocyte differentiation+++GO:0031507///heterochromatin assembly+++GO:0031508///pericentric heterochromatin assembly+++GO:0043066///negative regulation of apoptotic process+++GO:0046651///lymphocyte proliferation+++GO:0051301///cell division+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 15203 15203 'Heph' mRNA 217 191 174 2.53 2.17 2.17 1.68 1.19 1.03 2.29 1.3 167 116 97 194 126.6666667 0.007442898 -0.628173433 00860///Porphyrin metabolism+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004322///ferroxidase activity+++GO:0005507///copper ion binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0030218///erythrocyte differentiation+++GO:0055072///iron ion homeostasis 15204 15204 'Herc2' mRNA 1352 1260 984 4.47 4.1 3.49 3.05 3.05 3.17 4.02 3.09 1047 1026 1055 1198.666667 1042.666667 0.054352773 -0.207579051 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0032183///SUMO binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 15205 15205 'Hes1' mRNA 622 640 196 25.86 26.15 8.55 4.1 10.41 9.1 20.18666667 7.87 115 281 240 486 212 0.087302744 -1.176620787 03460///Fanconi anemia pathway+++04330///Notch signaling pathway+++04950///Maturity onset diabetes of the young+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05224///Breast cancer GO:0000785///chromatin+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043398///HLH domain binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:0051087///chaperone binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding+++GO:0071820///N-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0003143///embryonic heart tube morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003266///regulation of secondary heart field cardioblast proliferation+++GO:0003281///ventricular septum development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007389///pattern specification process+++GO:0008284///positive regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021537///telencephalon development+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0021557///oculomotor nerve development+++GO:0021558///trochlear nerve development+++GO:0021575///hindbrain morphogenesis+++GO:0021861///forebrain radial glial cell differentiation+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0021984///adenohypophysis development+++GO:0030324///lung development+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030901///midbrain development+++GO:0031016///pancreas development+++GO:0035019///somatic stem cell population maintenance+++GO:0035315///hair cell differentiation+++GO:0035909///aorta morphogenesis+++GO:0035910///ascending aorta morphogenesis+++GO:0042102///positive regulation of T cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043254///regulation of protein complex assembly+++GO:0043388///positive regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045977///positive regulation of mitotic cell cycle, embryonic+++GO:0046331///lateral inhibition+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048469///cell maturation+++GO:0048505///regulation of timing of cell differentiation+++GO:0048538///thymus development+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0048844///artery morphogenesis+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060164///regulation of timing of neuron differentiation+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060412///ventricular septum morphogenesis+++GO:0060675///ureteric bud morphogenesis+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061009///common bile duct development+++GO:0061106///negative regulation of stomach neuroendocrine cell differentiation+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:0072012///glomerulus vasculature development+++GO:0072049///comma-shaped body morphogenesis+++GO:0072050///S-shaped body morphogenesis+++GO:0072141///renal interstitial fibroblast development+++GO:0072282///metanephric nephron tubule morphogenesis+++GO:0090102///cochlea development+++GO:0090162///establishment of epithelial cell polarity+++GO:0090281///negative regulation of calcium ion import+++GO:0097084///vascular smooth muscle cell development+++GO:0097150///neuronal stem cell population maintenance+++GO:1905934///negative regulation of cell fate determination+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000227///negative regulation of pancreatic A cell differentiation+++GO:2000737///negative regulation of stem cell differentiation+++GO:2000974///negative regulation of pro-B cell differentiation+++GO:2000978///negative regulation of forebrain neuron differentiation+++GO:2000981///negative regulation of inner ear receptor cell differentiation" 15206 15206 'Hes2' mRNA 0 0 4 0 0 0.08 0 0 0.04 0.026666667 0.013333333 0 0 2 1.333333333 0.666666667 0.787753832 -1.075318359 05165///Human papillomavirus infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050767///regulation of neurogenesis" 15207 15207 'Hes3' mRNA 10 2 2 0.25 0.04 0.07 0.04 0 0.04 0.12 0.026666667 2 0 2 4.666666667 1.333333333 0.317716631 -1.813420597 05165///Human papillomavirus infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:0071820///N-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0009952///anterior/posterior pattern specification+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0021557///oculomotor nerve development+++GO:0021558///trochlear nerve development+++GO:0021575///hindbrain morphogenesis+++GO:0021915///neural tube development+++GO:0030901///midbrain development+++GO:0045665///negative regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050767///regulation of neurogenesis+++GO:0060164///regulation of timing of neuron differentiation" 15208 15208 'Hes5' mRNA 27 30 17 0.63 0.81 0.86 0.09 0.04 0.09 0.766666667 0.073333333 3 1 5 24.66666667 3 1.72E-04 -3.042658236 04330///Notch signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0014003///oligodendrocyte development+++GO:0021537///telencephalon development+++GO:0021781///glial cell fate commitment+++GO:0021861///forebrain radial glial cell differentiation+++GO:0021915///neural tube development+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031641///regulation of myelination+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043010///camera-type eye development+++GO:0045595///regulation of cell differentiation+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048469///cell maturation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048708///astrocyte differentiation+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0051216///cartilage development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0065003///protein-containing complex assembly+++GO:0072049///comma-shaped body morphogenesis+++GO:0072050///S-shaped body morphogenesis+++GO:0072086///specification of loop of Henle identity+++GO:0072282///metanephric nephron tubule morphogenesis+++GO:0090162///establishment of epithelial cell polarity+++GO:0097150///neuronal stem cell population maintenance+++GO:2000737///negative regulation of stem cell differentiation+++GO:2000974///negative regulation of pro-B cell differentiation+++GO:2000978///negative regulation of forebrain neuron differentiation+++GO:2000981///negative regulation of inner ear receptor cell differentiation" 15211 15211 'Hexa' mRNA 3593 3531.87 3479.93 102.63 99.34 105.46 293.54 290.47 273.91 102.4766667 285.9733333 11819.93 11423 10679.8 3534.933333 11307.57667 9.43E-187 1.665240769 00511///Other glycan degradation+++00513///Various types of N-glycan biosynthesis+++00520///Amino sugar and nucleotide sugar metabolism+++00531///Glycosaminoglycan degradation+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00604///Glycosphingolipid biosynthesis - ganglio series+++04142///Lysosome GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042582///azurophil granule+++GO:0043231///intracellular membrane-bounded organelle "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046982///protein heterodimerization activity+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity" GO:0001501///skeletal system development+++GO:0005975///carbohydrate metabolic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006689///ganglioside catabolic process+++GO:0007040///lysosome organization+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008152///metabolic process+++GO:0019915///lipid storage+++GO:0019953///sexual reproduction+++GO:0030203///glycosaminoglycan metabolic process+++GO:0042552///myelination+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050884///neuromuscular process controlling posture+++GO:0050885///neuromuscular process controlling balance+++GO:0060395///SMAD protein signal transduction 15212 15212 'Hexb' mRNA 2172.16 2179.33 2178.5 65.28 64.53 69.45 261.46 262.05 256.98 66.42 260.1633333 10001.55 9785.19 9513.86 2176.663333 9766.866667 0 2.153312044 00511///Other glycan degradation+++00513///Various types of N-glycan biosynthesis+++00520///Amino sugar and nucleotide sugar metabolism+++00531///Glycosaminoglycan degradation+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00604///Glycosphingolipid biosynthesis - ganglio series+++04142///Lysosome GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042582///azurophil granule+++GO:0060473///cortical granule "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0015929///hexosaminidase activity+++GO:0016231///beta-N-acetylglucosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity" GO:0001501///skeletal system development+++GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0007040///lysosome organization+++GO:0007338///single fertilization+++GO:0007341///penetration of zona pellucida+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0008049///male courtship behavior+++GO:0008152///metabolic process+++GO:0008360///regulation of cell shape+++GO:0008654///phospholipid biosynthetic process+++GO:0009313///oligosaccharide catabolic process+++GO:0019915///lipid storage+++GO:0019953///sexual reproduction+++GO:0030203///glycosaminoglycan metabolic process+++GO:0031323///regulation of cellular metabolic process+++GO:0042552///myelination+++GO:0043615///astrocyte cell migration+++GO:0044267///cellular protein metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process 15213 15213 'Hey1' mRNA 697 717 686 17.82 18.21 18.73 6 6.54 6.68 18.25333333 6.406666667 270 280 278 700 276 4.58E-31 -1.354102547 04330///Notch signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0002076///osteoblast development+++GO:0003151///outflow tract morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003190///atrioventricular valve formation+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003199///endocardial cushion to mesenchymal transition involved in heart valve formation+++GO:0003203///endocardial cushion morphogenesis+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014031///mesenchymal cell development+++GO:0035912///dorsal aorta morphogenesis+++GO:0036304///umbilical cord morphogenesis+++GO:0045607///regulation of inner ear auditory receptor cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060411///cardiac septum morphogenesis+++GO:0060412///ventricular septum morphogenesis+++GO:0060675///ureteric bud morphogenesis+++GO:0060716///labyrinthine layer blood vessel development+++GO:0060840///artery development+++GO:0060842///arterial endothelial cell differentiation+++GO:0061314///Notch signaling involved in heart development+++GO:0070168///negative regulation of biomineral tissue development+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0072049///comma-shaped body morphogenesis+++GO:0072050///S-shaped body morphogenesis+++GO:0072087///renal vesicle development+++GO:0072359///circulatory system development+++GO:0090162///establishment of epithelial cell polarity+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2000820///negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation+++GO:2001212///regulation of vasculogenesis" 15214 15214 'Hey2' mRNA 365 426 316 8.02 9.22 7.37 1.91 1.35 1.84 8.203333333 1.7 100 69 93 369 87.33333333 5.43E-29 -2.088003076 04330///Notch signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016580///Sin3 complex+++GO:0017053///transcriptional repressor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0003150///muscular septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003171///atrioventricular valve development+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003186///tricuspid valve morphogenesis+++GO:0003195///tricuspid valve formation+++GO:0003199///endocardial cushion to mesenchymal transition involved in heart valve formation+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003300///cardiac muscle hypertrophy+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007507///heart development+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010460///positive regulation of heart rate+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0014031///mesenchymal cell development+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0035910///ascending aorta morphogenesis+++GO:0035912///dorsal aorta morphogenesis+++GO:0036304///umbilical cord morphogenesis+++GO:0045165///cell fate commitment+++GO:0045607///regulation of inner ear auditory receptor cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050767///regulation of neurogenesis+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060347///heart trabecula formation+++GO:0060411///cardiac septum morphogenesis+++GO:0060412///ventricular septum morphogenesis+++GO:0060413///atrial septum morphogenesis+++GO:0060633///negative regulation of transcription initiation from RNA polymerase II promoter+++GO:0060716///labyrinthine layer blood vessel development+++GO:0060840///artery development+++GO:0060842///arterial endothelial cell differentiation+++GO:0060948///cardiac vascular smooth muscle cell development+++GO:0060977///coronary vasculature morphogenesis+++GO:0061156///pulmonary artery morphogenesis+++GO:0061314///Notch signaling involved in heart development+++GO:0065004///protein-DNA complex assembly+++GO:0070168///negative regulation of biomineral tissue development+++GO:0072359///circulatory system development+++GO:0090102///cochlea development+++GO:0097084///vascular smooth muscle cell development+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2000820///negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation+++GO:2001212///regulation of vasculogenesis" 15216 15216 'Hfe' mRNA 683.96 717.39 666.41 12.31 12.67 12.64 24.11 24.32 24.12 12.54 24.18333333 1515.94 1506.74 1486.25 689.2533333 1502.976667 2.89E-41 1.114238821 GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045177///apical part of cell+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:1990357///terminal web+++GO:1990712///HFE-transferrin receptor complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0039706///co-receptor binding+++GO:1990459///transferrin receptor binding "GO:0002626///negative regulation of T cell antigen processing and presentation+++GO:0002725///negative regulation of T cell cytokine production+++GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006953///acute-phase response+++GO:0007565///female pregnancy+++GO:0010039///response to iron ion+++GO:0010106///cellular response to iron ion starvation+++GO:0010628///positive regulation of gene expression+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034756///regulation of iron ion transport+++GO:0042446///hormone biosynthetic process+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0055072///iron ion homeostasis+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0071281///cellular response to iron ion+++GO:0090277///positive regulation of peptide hormone secretion+++GO:0097421///liver regeneration+++GO:0098711///iron ion import across plasma membrane+++GO:1900121///negative regulation of receptor binding+++GO:1900122///positive regulation of receptor binding+++GO:1904283///negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:1904434///positive regulation of ferrous iron binding+++GO:1904437///positive regulation of transferrin receptor binding+++GO:1990641///response to iron ion starvation+++GO:2000008///regulation of protein localization to cell surface+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000273///positive regulation of signaling receptor activity+++GO:2001186///negative regulation of CD8-positive, alpha-beta T cell activation" 15218 15218 'Foxn1' mRNA 56 46 42 0.94 0.75 0.73 0.37 0.43 0.33 0.806666667 0.376666667 25 28 22 48 25 0.026871613 -0.949510116 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001942///hair follicle development+++GO:0002260///lymphocyte homeostasis+++GO:0002360///T cell lineage commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008544///epidermis development+++GO:0010468///regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0035878///nail development+++GO:0043029///T cell homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0048538///thymus development+++GO:0051798///positive regulation of hair follicle development+++GO:0097535///lymphoid lineage cell migration into thymus+++GO:0097536///thymus epithelium morphogenesis+++GO:1902232///regulation of positive thymic T cell selection" 15220 15220 'Foxq1' mRNA 122 108 20 2.4 2.09 0.42 0.17 0.58 0.48 1.636666667 0.41 10 33 27 83.33333333 23.33333333 0.001231029 -1.811864376 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0043524///negative regulation of neuron apoptotic process" 15221 15221 'Foxd3' mRNA 40 44 10 0.94 1.02 0.25 0.14 0.4 0.36 0.736666667 0.3 7 19 17 31.33333333 14.33333333 0.106765687 -1.109162746 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001829///trophectodermal cell differentiation+++GO:0001892///embryonic placenta development+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor" 15223 15223 'Foxj1' mRNA 1312 1256 653 28.1 26.38 14.76 2.82 2.49 2.61 23.08 2.64 152 131 136 1073.666667 139.6666667 2.99E-23 -2.94093209 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002508///central tolerance induction+++GO:0002635///negative regulation of germinal center formation+++GO:0002897///positive regulation of central B cell tolerance induction+++GO:0002924///negative regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0030030///cell projection organization+++GO:0030036///actin cytoskeleton organization+++GO:0030856///regulation of epithelial cell differentiation+++GO:0032053///ciliary basal body organization+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0034613///cellular protein localization+++GO:0035082///axoneme assembly+++GO:0035089///establishment of apical/basal cell polarity+++GO:0035502///metanephric part of ureteric bud development+++GO:0042130///negative regulation of T cell proliferation+++GO:0044458///motile cilium assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050869///negative regulation of B cell activation+++GO:0050900///leukocyte migration+++GO:0060271///cilium assembly+++GO:0060428///lung epithelium development+++GO:0060429///epithelium development+++GO:0060972///left/right pattern formation+++GO:0072016///glomerular parietal epithelial cell development+++GO:0090630///activation of GTPase activity+++GO:1901248///positive regulation of lung ciliated cell differentiation" 15227 15227 'Foxf1' mRNA 1 3 6 0.02 0.07 0.15 0.08 0.06 0.04 0.08 0.06 4 3 2 3.333333333 3 0.916000669 -0.190234265 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001763///morphogenesis of a branching structure+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003197///endocardial cushion development+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007494///midgut development+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0009887///animal organ morphogenesis+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0014822///detection of wounding+++GO:0030198///extracellular matrix organization+++GO:0030323///respiratory tube development+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0031016///pancreas development+++GO:0043305///negative regulation of mast cell degranulation+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048371///lateral mesodermal cell differentiation+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048565///digestive tract development+++GO:0048566///embryonic digestive tract development+++GO:0048613///embryonic ectodermal digestive tract morphogenesis+++GO:0048617///embryonic foregut morphogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0051145///smooth muscle cell differentiation+++GO:0060425///lung morphogenesis+++GO:0060426///lung vasculature development+++GO:0060438///trachea development+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060461///right lung morphogenesis+++GO:0060463///lung lobe morphogenesis+++GO:0060841///venous blood vessel development+++GO:0061030///epithelial cell differentiation involved in mammary gland alveolus development+++GO:0071345///cellular response to cytokine stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0072189///ureter development+++GO:0090131///mesenchyme migration+++GO:0097070///ductus arteriosus closure+++GO:0098609///cell-cell adhesion" 15228 15228 'Foxg1' mRNA 50 33 45 0.93 0.59 0.89 0.42 0.18 0.42 0.803333333 0.34 26 11 25 42.66666667 20.66666667 0.034024729 -1.065867383 04068///FoxO signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007420///brain development+++GO:0007568///aging+++GO:0009953///dorsal/ventral pattern formation+++GO:0010468///regulation of gene expression+++GO:0016199///axon midline choice point recognition+++GO:0021852///pyramidal neuron migration+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0030900///forebrain development+++GO:0042472///inner ear morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048664///neuron fate determination+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0051726///regulation of cell cycle+++GO:2000177///regulation of neural precursor cell proliferation" 15229 15229 'Foxd1' mRNA 6 0 3 0.14 0 0.07 0.04 0.1 0.12 0.07 0.086666667 2 5 6 3 4.333333333 0.782166408 0.519861848 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008301///DNA binding, bending+++GO:0043565///sequence-specific DNA binding" "GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0009653///anatomical structure morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032275///luteinizing hormone secretion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060678///dichotomous subdivision of terminal units involved in ureteric bud branching+++GO:0072076///nephrogenic mesenchyme development+++GO:0072210///metanephric nephron development+++GO:0072213///metanephric capsule development+++GO:0072267///metanephric capsule specification+++GO:0072268///pattern specification involved in metanephros development+++GO:0090184///positive regulation of kidney development" 15233 15233 'Hgd' mRNA 26 38 25 0.88 1.27 0.9 1.3 1.57 0.92 1.016666667 1.263333333 44 52 30 29.66666667 42 0.317550219 0.495831934 00350///Tyrosine metabolism GO:0005737///cytoplasm "GO:0004411///homogentisate 1,2-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006520///cellular amino acid metabolic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006570///tyrosine metabolic process+++GO:0006572///tyrosine catabolic process 15234 15234 'Hgf' mRNA 351 278 283 4.74 3.6 3.46 7.94 7.82 7.72 3.933333333 7.826666667 719 648 732 304 699.6666667 5.30E-21 1.191161572 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++05144///Malaria+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma+++05218///Melanoma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0000187///activation of MAPK activity+++GO:0000902///cell morphogenesis+++GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030212///hyaluronan metabolic process+++GO:0030335///positive regulation of cell migration+++GO:0031100///animal organ regeneration+++GO:0031643///positive regulation of myelination+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045766///positive regulation of angiogenesis+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0050673///epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0051450///myoblast proliferation+++GO:0060326///cell chemotaxis+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0070572///positive regulation of neuron projection regeneration+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:1900744///regulation of p38MAPK cascade+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902947///regulation of tau-protein kinase activity+++GO:2000573///positive regulation of DNA biosynthetic process 15235 15235 'Mst1' mRNA 24 17 27 0.95 0.77 1.22 0.3 0.13 0.38 0.98 0.27 11 3 10 22.66666667 8 0.033364647 -1.528227979 04020///Calcium signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005773///vacuole GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0019899///enzyme binding+++GO:0030971///receptor tyrosine kinase binding GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0007566///embryo implantation+++GO:0010628///positive regulation of gene expression+++GO:0010758///regulation of macrophage chemotaxis+++GO:0030317///flagellated sperm motility+++GO:0030879///mammary gland development+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0035978///histone H2A-S139 phosphorylation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046425///regulation of JAK-STAT cascade+++GO:0060763///mammary duct terminal end bud growth+++GO:0071456///cellular response to hypoxia+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:2000479///regulation of cAMP-dependent protein kinase activity 15239 15239 'Hgs' mRNA 2649 2692 2599 50.01 50.07 52.16 44.04 39.79 40.78 50.74666667 41.53666667 2676 2362 2401 2646.666667 2479.666667 0.164100321 -0.107025556 04144///Endocytosis+++04145///Phagosome GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031901///early endosome membrane+++GO:0032585///multivesicular body membrane+++GO:0033565///ESCRT-0 complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046872///metal ion binding+++GO:0140036///ubiquitin-dependent protein binding GO:0006622///protein targeting to lysosome+++GO:0006886///intracellular protein transport+++GO:0008333///endosome to lysosome transport+++GO:0010324///membrane invagination+++GO:0010628///positive regulation of gene expression+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0015031///protein transport+++GO:0016525///negative regulation of angiogenesis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0043405///regulation of MAP kinase activity+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0072657///protein localization to membrane+++GO:1903543///positive regulation of exosomal secretion 15242 15242 'Hhex' mRNA 46 48 69 1.5 1.54 2.39 8.4 7.67 8.36 1.81 8.143333333 296 264 285 54.33333333 281.6666667 1.54E-26 2.355404507 04950///Maturity onset diabetes of the young+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0008301///DNA binding, bending+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0070491///repressing transcription factor binding+++GO:0071837///HMG box domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0002009///morphogenesis of an epithelium+++GO:0002573///myeloid leukocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006406///mRNA export from nucleus+++GO:0007165///signal transduction+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0016055///Wnt signaling pathway+++GO:0016525///negative regulation of angiogenesis+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0022027///interkinetic nuclear migration+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030183///B cell differentiation+++GO:0030878///thyroid gland development+++GO:0030900///forebrain development+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031016///pancreas development+++GO:0034504///protein localization to nucleus+++GO:0035050///embryonic heart tube development+++GO:0035264///multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048729///tissue morphogenesis+++GO:0048853///forebrain morphogenesis+++GO:0060431///primary lung bud formation+++GO:0061009///common bile duct development+++GO:0061010///gall bladder development+++GO:0061011///hepatic duct development+++GO:0061017///hepatoblast differentiation+++GO:0070365///hepatocyte differentiation+++GO:0070663///regulation of leukocyte proliferation+++GO:0071103///DNA conformation change+++GO:0090009///primitive streak formation+++GO:0090263///positive regulation of canonical Wnt signaling pathway" 15245 15245 'Hhip' mRNA 31 21 39 0.26 0.19 0.44 1.57 1.05 1.07 0.296666667 1.23 144 111 110 30.33333333 121.6666667 7.11E-10 1.981815474 04024///cAMP signaling pathway+++04340///Hedgehog signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0097108///hedgehog family protein binding GO:0007165///signal transduction+++GO:0007405///neuroblast proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009953///dorsal/ventral pattern formation+++GO:0009968///negative regulation of signal transduction+++GO:0016525///negative regulation of angiogenesis+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis 15247 15247 'Mfsd14a' mRNA 2119.08 2203.12 2362.62 41.38 42.6 48.99 36.06 35.5 35.15 44.32333333 35.57 2126.96 2030.43 2005.83 2228.273333 2054.406667 0.148995692 -0.132648471 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0001675///acrosome assembly+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007289///spermatid nucleus differentiation+++GO:0030382///sperm mitochondrion organization+++GO:0055085///transmembrane transport 15248 15248 'Hic1' mRNA 160.53 160.95 69.65 1.99 1.89 0.64 1.57 2.33 2.54 1.506666667 2.146666667 159.11 223.42 213 130.3766667 198.51 0.03051641 0.620133397 GO:0000785///chromatin+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator" 15251 15251 'Hif1a' mRNA 4971 5344 5249 60.35 63.98 68.37 41.84 39.3 40.73 64.23333333 40.62333333 3919 3612 3680 5188 3737 3.63E-14 -0.486888382 04066///HIF-1 signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04212///Longevity regulating pathway - worm+++04361///Axon regeneration+++04659///Th17 cell differentiation+++04919///Thyroid hormone signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0031514///motile cilium+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:1904115///axon cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035035///histone acetyltransferase binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000302///response to reactive oxygen species+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001666///response to hypoxia+++GO:0001678///cellular glucose homeostasis+++GO:0001755///neural crest cell migration+++GO:0001837///epithelial to mesenchymal transition+++GO:0001892///embryonic placenta development+++GO:0001922///B-1 B cell homeostasis+++GO:0001944///vasculature development+++GO:0001947///heart looping+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002248///connective tissue replacement involved in inflammatory response wound healing+++GO:0003151///outflow tract morphogenesis+++GO:0003208///cardiac ventricle morphogenesis+++GO:0006089///lactate metabolic process+++GO:0006110///regulation of glycolytic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006879///cellular iron ion homeostasis+++GO:0007165///signal transduction+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0010039///response to iron ion+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010573///vascular endothelial growth factor production+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0014850///response to muscle activity+++GO:0016239///positive regulation of macroautophagy+++GO:0019896///axonal transport of mitochondrion+++GO:0021502///neural fold elevation formation+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030502///negative regulation of bone mineralization+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0032364///oxygen homeostasis+++GO:0032909///regulation of transforming growth factor beta2 production+++GO:0032963///collagen metabolic process+++GO:0035162///embryonic hemopoiesis+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042127///regulation of cell proliferation+++GO:0042541///hemoglobin biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045906///negative regulation of vasoconstriction+++GO:0045926///negative regulation of growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046716///muscle cell cellular homeostasis+++GO:0046886///positive regulation of hormone biosynthetic process+++GO:0048514///blood vessel morphogenesis+++GO:0048546///digestive tract morphogenesis+++GO:0048593///camera-type eye morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0051216///cartilage development+++GO:0051541///elastin metabolic process+++GO:0060574///intestinal epithelial cell maturation+++GO:0060992///response to fungicide+++GO:0061030///epithelial cell differentiation involved in mammary gland alveolus development+++GO:0061072///iris morphogenesis+++GO:0061298///retina vasculature development in camera-type eye+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0070101///positive regulation of chemokine-mediated signaling pathway+++GO:0070243///regulation of thymocyte apoptotic process+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0071347///cellular response to interleukin-1+++GO:0071456///cellular response to hypoxia+++GO:0071542///dopaminergic neuron differentiation+++GO:0097411///hypoxia-inducible factor-1alpha signaling pathway+++GO:0098586///cellular response to virus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:1903715///regulation of aerobic respiration+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000434///regulation of protein neddylation+++GO:2001054///negative regulation of mesenchymal cell apoptotic process" 15254 15254 'Hint1' mRNA 1315 1354 1254 152.09 155.74 153.95 259.01 286.25 283.34 153.9266667 276.2 2557 2748 2697 1307.666667 2667.333333 1.39E-44 1.018255513 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043530///adenosine 5'-monophosphoramidase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0009154///purine ribonucleotide catabolic process+++GO:0016926///protein desumoylation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator" 15257 15257 'Hipk1' mRNA 2932 3008 3242 19.88 20 23.34 18.43 16.7 18.22 21.07333333 17.78333333 3136 2780 3009 3060.666667 2975 0.576942438 -0.056739272 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007224///smoothened signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010842///retina layer formation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030182///neuron differentiation+++GO:0034333///adherens junction assembly+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043388///positive regulation of DNA binding+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060235///lens induction in camera-type eye+++GO:0061072///iris morphogenesis+++GO:0072577///endothelial cell apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway 15258 15258 'Hipk2' mRNA 3666.49 3455.98 3110.03 19.31 18.25 16.41 16.91 16.43 17.09 17.99 16.81 3990.08 3268.09 3824.48 3410.833333 3694.216667 0.22434919 0.104125773 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0090575///RNA polymerase II transcription factor complex GO:0000166///nucleotide binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046332///SMAD binding+++GO:0046790///virion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007628///adult walking behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0009952///anterior/posterior pattern specification+++GO:0010842///retina layer formation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030182///neuron differentiation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043388///positive regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0050882///voluntary musculoskeletal movement+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060235///lens induction in camera-type eye+++GO:0060395///SMAD protein signal transduction+++GO:0061072///iris morphogenesis+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process" 15259 15259 'Hipk3' mRNA 1893 1768 1449 13.31 12.22 10.81 8.85 7.93 8.71 12.11333333 8.496666667 1449 1269 1382 1703.333333 1366.666667 3.53E-04 -0.326116037 04218///Cellular senescence GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0016605///PML body GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0009299///mRNA transcription+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043508///negative regulation of JUN kinase activity 15260 15260 'Hira' mRNA 148 128.3 126 2.17 1.75 1.95 1.7 1.31 1.49 1.956666667 1.5 135 102.25 115 134.1 117.4166667 0.450578985 -0.204620875 GO:0000417///HIR complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0032991///protein-containing complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0042393///histone binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0001649///osteoblast differentiation+++GO:0006325///chromatin organization+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007369///gastrulation+++GO:0042692///muscle cell differentiation" 15267 15267 'H2ac18' mRNA 1243.59 1140.57 1162.45 177.91 162.76 176.55 223.23 272.04 234.97 172.4066667 243.4133333 1777.84 2104.24 1802.13 1182.203333 1894.736667 1.18E-12 0.670215952 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing 15270 15270 'H2ax' mRNA 535.83 499.66 484.57 23.59 21.71 22.63 29.9 33.42 29.56 22.64333333 30.96 779.96 850.36 745.69 506.6866667 792.0033333 8.52E-09 0.634682621 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000794///condensed nuclear chromosome+++GO:0001673///male germ cell nucleus+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005813///centrosome+++GO:0016607///nuclear speck+++GO:0035861///site of double-strand break+++GO:0090734///site of DNA damage" GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0046982///protein heterodimerization activity GO:0000077///DNA damage checkpoint+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006342///chromatin silencing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0021987///cerebral cortex development+++GO:0031507///heterochromatin assembly+++GO:0051321///meiotic cell cycle+++GO:0071480///cellular response to gamma radiation+++GO:0090398///cellular senescence 15273 15273 'Hivep2' mRNA 1203.72 1299.78 1140.06 6.41 6.8 6.45 5.3 4.75 5.52 6.553333333 5.19 1153.71 1000.74 1158.61 1214.52 1104.353333 0.128502834 -0.148537846 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II" 15275 15275 'Hk1' mRNA 3201 3408 3168 44.28 46.65 46.6 36.11 36.9 35.25 45.84333333 36.08666667 2992 2994 2846 3259 2944 0.01961026 -0.158017045 "00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++00524///Neomycin, kanamycin and gentamicin biosynthesis+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++04930///Type II diabetes mellitus+++04973///Carbohydrate digestion and absorption+++05131///Shigellosis+++05230///Central carbon metabolism in cancer" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0097228///sperm principal piece "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004340///glucokinase activity+++GO:0004396///hexokinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008865///fructokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019158///mannokinase activity+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0047931///glucosamine kinase activity" GO:0001678///cellular glucose homeostasis+++GO:0002376///immune system process+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002931///response to ischemia+++GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006013///mannose metabolic process+++GO:0006096///glycolytic process+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0010359///regulation of anion channel activity+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019318///hexose metabolic process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0046777///protein autophosphorylation+++GO:0046835///carbohydrate phosphorylation+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0061621///canonical glycolysis+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0072656///maintenance of protein location in mitochondrion 15277 15277 'Hk2' mRNA 783 808 829 7.56 7.67 8.49 10.63 9.18 10.01 7.906666667 9.94 1256 1070 1157 806.6666667 1161 1.25E-07 0.510793799 "00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++00524///Neomycin, kanamycin and gentamicin biosynthesis+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++04930///Type II diabetes mellitus+++04973///Carbohydrate digestion and absorption+++05131///Shigellosis+++05230///Central carbon metabolism in cancer" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004340///glucokinase activity+++GO:0004396///hexokinase activity+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008865///fructokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019158///mannokinase activity" GO:0001666///response to hypoxia+++GO:0001678///cellular glucose homeostasis+++GO:0002931///response to ischemia+++GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006096///glycolytic process+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0008637///apoptotic mitochondrial changes+++GO:0016310///phosphorylation+++GO:0019318///hexose metabolic process+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0045766///positive regulation of angiogenesis+++GO:0046324///regulation of glucose import+++GO:0046835///carbohydrate phosphorylation+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0072656///maintenance of protein location in mitochondrion+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000378///negative regulation of reactive oxygen species metabolic process 15278 15278 'Tfb2m' mRNA 562 555 568 12.94 12.5 13.76 11.87 11.34 12.26 13.06666667 11.82333333 596 559 597 561.6666667 584 0.778811629 0.043145835 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid "GO:0000179///rRNA (adenine-N6,N6-)-dimethyltransferase activity+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0034246///mitochondrial sequence-specific DNA-binding transcription factor activity" "GO:0000154///rRNA modification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006364///rRNA processing+++GO:0006390///mitochondrial transcription+++GO:0006391///transcription initiation from mitochondrial promoter+++GO:0031167///rRNA methylation+++GO:0032259///methylation" 15284 15284 'Hlx' mRNA 32 40 21 0.84 1.04 0.59 4.41 3.77 4.28 0.823333333 4.153333333 193 161 181 31 178.3333333 3.38E-20 2.518181179 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding" "GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0008284///positive regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0046622///positive regulation of organ growth+++GO:0048484///enteric nervous system development+++GO:0048513///animal organ development+++GO:0048557///embryonic digestive tract morphogenesis" 15288 15288 'Hmbs' mRNA 863 913 819 31.66 33.03 31.88 44.03 44.37 44.72 32.19 44.37333333 1378 1356 1355 865 1363 3.00E-15 0.645468144 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0048471///perinuclear region of cytoplasm GO:0004418///hydroxymethylbilane synthase activity+++GO:0004852///uroporphyrinogen-III synthase activity+++GO:0016740///transferase activity+++GO:0031406///carboxylic acid binding+++GO:0043176///amine binding GO:0001889///liver development+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0009410///response to xenobiotic stimulus+++GO:0018160///peptidyl-pyrromethane cofactor linkage+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0042493///response to drug 15289 15289 'Hmgb1' mRNA 9642.09 10115.5 10005.27 185.84 191.89 204.55 187.43 197.29 190.15 194.0933333 191.6233333 11182.12 11497.79 10985.84 9920.953333 11221.91667 0.008532286 0.165157395 03410///Base excision repair+++04140///Autophagy - animal+++04217///Necroptosis+++04613///Neutrophil extracellular trap formation GO:0000793///condensed chromosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0017053///transcriptional repressor complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0043005///neuron projection "GO:0000400///four-way junction DNA binding+++GO:0000401///open form four-way junction DNA binding+++GO:0000402///crossed form four-way junction DNA binding+++GO:0000405///bubble DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001530///lipopolysaccharide binding+++GO:0001786///phosphatidylserine binding+++GO:0003677///DNA binding+++GO:0003681///bent DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005125///cytokine activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008201///heparin binding+++GO:0008301///DNA binding, bending+++GO:0010858///calcium-dependent protein kinase regulator activity+++GO:0016829///lyase activity+++GO:0019958///C-X-C chemokine binding+++GO:0030295///protein kinase activator activity+++GO:0070182///DNA polymerase binding+++GO:0070491///repressing transcription factor binding+++GO:0097100///supercoiled DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001654///eye development+++GO:0001773///myeloid dendritic cell activation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002218///activation of innate immune response+++GO:0002250///adaptive immune response+++GO:0002270///plasmacytoid dendritic cell activation+++GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0002643///regulation of tolerance induction+++GO:0002840///regulation of T cell mediated immune response to tumor cell+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006342///chromatin silencing+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006914///autophagy+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010508///positive regulation of autophagy+++GO:0016458///gene silencing+++GO:0017055///negative regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0031497///chromatin assembly+++GO:0032072///regulation of restriction endodeoxyribonuclease activity+++GO:0032147///activation of protein kinase activity+++GO:0032392///DNA geometric change+++GO:0032425///positive regulation of mismatch repair+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033151///V(D)J recombination+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0035711///T-helper 1 cell activation+++GO:0035767///endothelial cell chemotaxis+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043277///apoptotic cell clearance+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043388///positive regulation of DNA binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045063///T-helper 1 cell differentiation+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045819///positive regulation of glycogen catabolic process+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0050930///induction of positive chemotaxis+++GO:0051106///positive regulation of DNA ligation+++GO:0051384///response to glucocorticoid+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090303///positive regulation of wound healing+++GO:0097350///neutrophil clearance+++GO:0098761///cellular response to interleukin-7+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000426///negative regulation of apoptotic cell clearance+++GO:2000819///regulation of nucleotide-excision repair+++GO:2001200///positive regulation of dendritic cell differentiation" 15312 15312 'Hmgn1' mRNA 4140 4154 4021 211.89 209.97 218.35 224.77 216.57 214.06 213.4033333 218.4666667 5040 4736 4641 4105 4805.666667 3.40E-04 0.214929246 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0031492///nucleosomal DNA binding "GO:0000720///pyrimidine dimer repair by nucleotide-excision repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010224///response to UV-B+++GO:0010225///response to UV-C+++GO:0040034///regulation of development, heterochronic+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0050678///regulation of epithelial cell proliferation+++GO:1901666///positive regulation of NAD+ ADP-ribosyltransferase activity" 15331 15331 'Hmgn2' mRNA 3028.64 3206.42 3120.94 147.09 153.75 160.81 153.31 160.43 149.14 153.8833333 154.2933333 3623.6 3698.41 3408.72 3118.666667 3576.91 0.009995635 0.18556534 GO:0000785///chromatin+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031640///killing of cells of other organism+++GO:0040034///regulation of development, heterochronic+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide" 15353 15353 'Hmg20b' mRNA 922 952 628 35.56 35.95 26.57 28.35 34.49 31.89 32.69333333 31.57666667 815 984 912 834 903.6666667 0.477546256 0.114196253 GO:0000794///condensed nuclear chromosome+++GO:0002111///BRCA2-BRAF35 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0035914///skeletal muscle cell differentiation+++GO:0045666///positive regulation of neuron differentiation" 15354 15354 'Hmgb3' mRNA 590 613 586 21.14 21.84 22.49 26.26 26.59 25.05 21.82333333 25.96666667 840 821 774 596.3333333 811.6666667 2.28E-05 0.432868026 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm "GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008301///DNA binding, bending" GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032392///DNA geometric change+++GO:0045087///innate immune response+++GO:0045578///negative regulation of B cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation 15356 15356 'Hmgcl' mRNA 1020 1125 1005 40.76 43.88 42.56 52.18 55.78 50.38 42.4 52.78 1505 1561 1407 1050 1491 7.28E-09 0.495445044 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism+++04146///Peroxisome" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005777///peroxisome+++GO:0032991///protein-containing complex GO:0000062///fatty-acyl-CoA binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004419///hydroxymethylglutaryl-CoA lyase activity+++GO:0005198///structural molecule activity+++GO:0016829///lyase activity+++GO:0016833///oxo-acid-lyase activity+++GO:0030145///manganese ion binding+++GO:0031406///carboxylic acid binding+++GO:0046872///metal ion binding GO:0001889///liver development+++GO:0006552///leucine catabolic process+++GO:0006629///lipid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0007005///mitochondrion organization+++GO:0007584///response to nutrient+++GO:0009790///embryo development+++GO:0042594///response to starvation+++GO:0046951///ketone body biosynthetic process+++GO:0070542///response to fatty acid 15357 15357 'Hmgcr' mRNA 1600 1526 1656 19.26 18.11 21.26 13.57 12.67 13.05 19.54333333 13.09666667 1289 1181 1201 1594 1223.666667 7.15E-06 -0.396259204 00900///Terpenoid backbone biosynthesis+++04152///AMPK signaling pathway+++04976///Bile secretion GO:0000139///Golgi membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004420///hydroxymethylglutaryl-CoA reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0032934///sterol binding+++GO:0042282///hydroxymethylglutaryl-CoA reductase activity+++GO:0042802///identical protein binding+++GO:0050661///NADP binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070402///NADPH binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006743///ubiquinone metabolic process+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008299///isoprenoid biosynthetic process+++GO:0008542///visual learning+++GO:0009790///embryo development+++GO:0010664///negative regulation of striated muscle cell apoptotic process+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0015936///coenzyme A metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0031667///response to nutrient levels+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032933///SREBP signaling pathway+++GO:0038183///bile acid signaling pathway+++GO:0042177///negative regulation of protein catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045445///myoblast differentiation+++GO:0045471///response to ethanol+++GO:0045907///positive regulation of vasoconstriction+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050709///negative regulation of protein secretion+++GO:0061045///negative regulation of wound healing+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070328///triglyceride homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070723///response to cholesterol+++GO:1900222///negative regulation of amyloid-beta clearance 15360 15360 'Hmgcs2' mRNA 2985 3269 3310 49.47 53.3 58.18 21.27 21.98 20.82 53.65 21.35666667 1477 1491 1400 3188 1456 1.12E-47 -1.144416544 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism+++00900///Terpenoid backbone biosynthesis+++03320///PPAR signaling pathway" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0004421///hydroxymethylglutaryl-CoA synthase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042802///identical protein binding" "GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0010142///farnesyl diphosphate biosynthetic process, mevalonate pathway+++GO:0016126///sterol biosynthetic process+++GO:0046951///ketone body biosynthetic process" 15361 15361 'Hmga1' mRNA 433.68 437.08 296.64 14.36 14.21 10.87 15.91 19.69 20.06 13.14666667 18.55333333 533.09 656.46 657.62 389.1333333 615.7233333 1.18E-05 0.660674849 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035985///senescence-associated heterochromatin focus+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0030527///structural constituent of chromatin+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity" "GO:0006284///base-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090402///oncogene-induced cell senescence+++GO:2000774///positive regulation of cellular senescence" 15364 15364 'Hmga2' mRNA 26 21 19 0.38 0.3 0.29 0.53 0.67 0.67 0.323333333 0.623333333 42 52 51 22 48.33333333 0.009548422 1.128459678 05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0032993///protein-DNA complex+++GO:0035985///senescence-associated heterochromatin focus+++GO:0071141///SMAD protein complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008301///DNA binding, bending+++GO:0019899///enzyme binding+++GO:0031492///nucleosomal DNA binding+++GO:0035497///cAMP response element binding+++GO:0035500///MH2 domain binding+++GO:0035501///MH1 domain binding+++GO:0046332///SMAD binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0070742///C2H2 zinc finger domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001837///epithelial to mesenchymal transition+++GO:0002062///chondrocyte differentiation+++GO:0003131///mesodermal-endodermal cell signaling+++GO:0006284///base-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009615///response to virus+++GO:0010564///regulation of cell cycle process+++GO:0010628///positive regulation of gene expression+++GO:0021846///cell proliferation in forebrain+++GO:0021983///pituitary gland development+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030261///chromosome condensation+++GO:0030325///adrenal gland development+++GO:0031052///chromosome breakage+++GO:0031507///heterochromatin assembly+++GO:0033144///negative regulation of intracellular steroid hormone receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035978///histone H2A-S139 phosphorylation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0035987///endodermal cell differentiation+++GO:0035988///chondrocyte proliferation+++GO:0040008///regulation of growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043922///negative regulation by host of viral transcription+++GO:0045444///fat cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048333///mesodermal cell differentiation+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048762///mesenchymal cell differentiation+++GO:0048863///stem cell differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0060123///regulation of growth hormone secretion+++GO:0060428///lung epithelium development+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060612///adipose tissue development+++GO:0060613///fat pad development+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090276///regulation of peptide hormone secretion+++GO:0090402///oncogene-induced cell senescence+++GO:2000036///regulation of stem cell population maintenance+++GO:2000648///positive regulation of stem cell proliferation+++GO:2000685///positive regulation of cellular response to X-ray+++GO:2000773///negative regulation of cellular senescence+++GO:2000774///positive regulation of cellular senescence+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining+++GO:2001038///regulation of cellular response to drug" 15366 15366 'Hmmr' mRNA 16.21 4.29 13.1 0.23 0.06 0.19 3.14 2.83 2.92 0.16 2.963333333 261.81 230.66 235.75 11.2 242.74 9.73E-41 4.44436332 04512///ECM-receptor interaction GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0015630///microtubule cytoskeleton GO:0005540///hyaluronic acid binding 15368 15368 'Hmox1' mRNA 442 456 441 16.45 16.74 17.41 113.91 101.49 106.42 16.86666667 107.2733333 3516 3057 3178 446.3333333 3250.333333 8.28E-277 2.851575953 00860///Porphyrin metabolism+++04066///HIF-1 signaling pathway+++04216///Ferroptosis+++04978///Mineral absorption+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004392///heme oxygenase (decyclizing) activity+++GO:0004630///phospholipase D activity+++GO:0005198///structural molecule activity+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0002246///wound healing involved in inflammatory response+++GO:0006788///heme oxidation+++GO:0006879///cellular iron ion homeostasis+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007264///small GTPase mediated signal transduction+++GO:0008217///regulation of blood pressure+++GO:0008219///cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0016239///positive regulation of macroautophagy+++GO:0016242///negative regulation of macroautophagy+++GO:0031670///cellular response to nutrient+++GO:0032764///negative regulation of mast cell cytokine production+++GO:0034101///erythrocyte homeostasis+++GO:0034395///regulation of transcription from RNA polymerase II promoter in response to iron+++GO:0034605///cellular response to heat+++GO:0035094///response to nicotine+++GO:0035556///intracellular signal transduction+++GO:0042167///heme catabolic process+++GO:0042168///heme metabolic process+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043305///negative regulation of mast cell degranulation+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0043627///response to estrogen+++GO:0045766///positive regulation of angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0055072///iron ion homeostasis+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071276///cellular response to cadmium ion+++GO:0071456///cellular response to hypoxia+++GO:0072719///cellular response to cisplatin+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0097421///liver regeneration+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation 15369 15369 'Hmox2' mRNA 1508.55 1650.32 1500.49 73.5 78.83 77.92 109.83 106.8 101.19 76.75 105.94 2631.03 2462.01 2339.71 1553.12 2477.583333 6.28E-20 0.662322713 00860///Porphyrin metabolism+++04978///Mineral absorption GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004392///heme oxygenase (decyclizing) activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0006788///heme oxidation+++GO:0006979///response to oxidative stress+++GO:0042167///heme catabolic process+++GO:0055072///iron ion homeostasis 15370 15370 'Nr4a1' mRNA 1089 1188 1091 24.35 26.04 25.85 15.99 15.44 16.26 25.41333333 15.89666667 828 776 816 1122.666667 806.6666667 4.66E-08 -0.488527347 04010///MAPK signaling pathway+++04151///PI3K-Akt signaling pathway+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0098793///presynapse "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001975///response to amphetamine+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0010035///response to inorganic substance+++GO:0014860///neurotransmitter secretion involved in regulation of skeletal muscle contraction+++GO:0030522///intracellular receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0035767///endothelial cell chemotaxis+++GO:0035914///skeletal muscle cell differentiation+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045444///fat cell differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051602///response to electrical stimulus+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0071310///cellular response to organic substance+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus" 15372 15372 'Hmx2' mRNA 290 275 276 5.57 5.2 5.62 4.29 4.02 4.36 5.463333333 4.223333333 258 235 253 280.3333333 248.6666667 0.295853596 -0.185499776 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0042472///inner ear morphogenesis+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 15373 15373 'Hmx3' mRNA 986 938 603 23 22.81 13.84 9.25 9.5 10.47 19.88333333 9.74 505 470 539 842.3333333 504.6666667 2.54E-07 -0.741552461 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007566///embryo implantation+++GO:0030154///cell differentiation+++GO:0042472///inner ear morphogenesis+++GO:0043583///ear development+++GO:0050885///neuromuscular process controlling balance+++GO:0060135///maternal process involved in female pregnancy" 15374 15374 'Jpt1' mRNA 1238 1280 1285 53.31 54.39 58.71 126.3 126.69 130.88 55.47 127.9566667 3368 3296 3376 1267.666667 3346.666667 1.52E-88 1.387811839 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function GO:0008150///biological_process 15375 15375 'Foxa1' mRNA 0 1 0 0 0.02 0 0.06 0 0.14 0.006666667 0.066666667 4 0 9 0.333333333 4.333333333 0.120830075 3.580026464 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005902///microvillus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0009653///anatomical structure morphogenesis+++GO:0010468///regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0032355///response to estradiol+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0035239///tube morphogenesis+++GO:0042445///hormone metabolic process+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048665///neuron fate specification+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0060425///lung morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060487///lung epithelial cell differentiation+++GO:0060528///secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development+++GO:0060738///epithelial-mesenchymal signaling involved in prostate gland development+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060741///prostate gland stromal morphogenesis+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0061144///alveolar secondary septum development+++GO:0061448///connective tissue development+++GO:1902691///respiratory basal cell differentiation" 15377 15377 'Foxa3' mRNA 2 6 2 0.06 0.16 0.06 0.05 0 0.03 0.093333333 0.026666667 2 0 1 3.333333333 1 0.40354299 -1.744221385 04950///Maturity onset diabetes of the young GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001678///cellular glucose homeostasis+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0009267///cellular response to starvation+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0070368///positive regulation of hepatocyte differentiation" 15378 15378 'Hnf4a' mRNA 1 0 0 0.01 0 0 0 0.01 0 0.003333333 0.003333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04152///AMPK signaling pathway+++04950///Maturity onset diabetes of the young GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000062///fatty-acyl-CoA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050544///arachidonic acid binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:0070540///stearic acid binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003323///type B pancreatic cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006591///ornithine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0007164///establishment of tissue polarity+++GO:0007548///sex differentiation+++GO:0007596///blood coagulation+++GO:0008285///negative regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0010470///regulation of gastrulation+++GO:0019216///regulation of lipid metabolic process+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030522///intracellular receptor signaling pathway+++GO:0032534///regulation of microvillus assembly+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045216///cell-cell junction organization+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048856///anatomical structure development+++GO:0050796///regulation of insulin secretion+++GO:0055088///lipid homeostasis+++GO:0055091///phospholipid homeostasis+++GO:0060395///SMAD protein signal transduction+++GO:0070328///triglyceride homeostasis+++GO:0070365///hepatocyte differentiation+++GO:1902569///negative regulation of activation of Janus kinase activity" 15381 15381 'Hnrnpc' mRNA 3193 3124.99 3187.79 63.39 61.18 67 83.87 76.95 84.35 63.85666667 81.72333333 4824 4335 4733 3168.593333 4630.666667 2.97E-16 0.533964154 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005697///telomerase holoenzyme complex+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0032991///protein-containing complex+++GO:0045120///pronucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:1990826///nucleoplasmic periphery of the nuclear pore complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0004857///enzyme inhibitor activity+++GO:0008266///poly(U) RNA binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0070034///telomerase RNA binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:1990827///deaminase binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0043086///negative regulation of catalytic activity+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0090367///negative regulation of mRNA modification" 15382 15382 'Hnrnpa1' mRNA 2855.83 2748.84 2724.78 88.77 84.32 90.39 87.28 80.25 84.16 87.82666667 83.89666667 3187.92 2853.95 2973.89 2776.483333 3005.253333 0.17402564 0.10126498 03040///Spliceosome+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071013///catalytic step 2 spliceosome+++GO:1990826///nucleoplasmic periphery of the nuclear pore complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0019904///protein domain specific binding+++GO:0033592///RNA strand annealing activity+++GO:0035198///miRNA binding+++GO:0036002///pre-mRNA binding+++GO:0036310///annealing helicase activity+++GO:0042802///identical protein binding+++GO:0061752///telomeric repeat-containing RNA binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:1990814///DNA/DNA annealing activity+++GO:1990825///sequence-specific mRNA binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035865///cellular response to potassium ion+++GO:0042149///cellular response to glucose starvation+++GO:0045760///positive regulation of action potential+++GO:0051028///mRNA transport+++GO:0051168///nuclear export+++GO:0051170///import into nucleus+++GO:1903936///cellular response to sodium arsenite+++GO:1904577///cellular response to tunicamycin" 15384 15384 'Hnrnpab' mRNA 624.42 611.42 349.79 14.18 13.71 8.47 17.15 15.35 18.78 12.12 17.09333333 867.7 763.73 921.5 528.5433333 850.9766667 1.43E-05 0.686419865 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0099523///presynaptic cytosol+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001837///epithelial to mesenchymal transition+++GO:0010468///regulation of gene expression+++GO:0045893///positive regulation of transcription, DNA-templated" 15387 15387 'Hnrnpk' mRNA 12225 12712 13014 238.99 244.62 270.43 262.59 267.87 249.23 251.3466667 259.8966667 15419 15407 14194 12650.33333 15006.66667 4.49E-04 0.232576317 03040///Spliceosome+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer GO:0000785///chromatin+++GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0010494///cytoplasmic stress granule+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0032993///protein-DNA complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0071013///catalytic step 2 spliceosome+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042805///actinin binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051117///ATPase binding+++GO:1990715///mRNA CDS binding+++GO:1990829///C-rich single-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0021987///cerebral cortex development+++GO:0032091///negative regulation of protein binding+++GO:0032869///cellular response to insulin stimulus+++GO:0033120///positive regulation of RNA splicing+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050806///positive regulation of synaptic transmission+++GO:0060999///positive regulation of dendritic spine development+++GO:0090129///positive regulation of synapse maturation+++GO:0099175///regulation of postsynapse organization+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1902165///regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1903861///positive regulation of dendrite extension+++GO:1904322///cellular response to forskolin+++GO:1905599///positive regulation of low-density lipoprotein receptor activity+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000173///negative regulation of branching morphogenesis of a nerve" 15388 15388 'Hnrnpl' mRNA 1782 1580 1071 44.47 38.48 28.08 26.55 27.35 28.13 37.01 27.34333333 1227 1230 1264 1477.666667 1240.333333 0.056503091 -0.254977438 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035770///ribonucleoprotein granule+++GO:0045120///pronucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0097157///pre-mRNA intronic binding+++GO:1990715///mRNA CDS binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0034198///cellular response to amino acid starvation+++GO:0043484///regulation of RNA splicing+++GO:0045727///positive regulation of translation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:1902416///positive regulation of mRNA binding" 15394 15394 'Hoxa1' mRNA 2 0 3 0.05 0 0.08 0 0.07 0.11 0.043333333 0.06 0 3 5 1.666666667 2.666666667 0.797199703 0.650944416 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0007634///optokinetic behavior+++GO:0008045///motor neuron axon guidance+++GO:0009653///anatomical structure morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0021569///rhombomere 3 development+++GO:0021570///rhombomere 4 development+++GO:0021571///rhombomere 5 development+++GO:0021599///abducens nerve formation+++GO:0021612///facial nerve structural organization+++GO:0021754///facial nucleus development+++GO:0021953///central nervous system neuron differentiation+++GO:0030902///hindbrain development+++GO:0042472///inner ear morphogenesis+++GO:0042473///outer ear morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048839///inner ear development+++GO:0048844///artery morphogenesis+++GO:0050795///regulation of behavior+++GO:0050890///cognition+++GO:0050905///neuromuscular process+++GO:0060840///artery development+++GO:0060876///semicircular canal formation+++GO:0071300///cellular response to retinoic acid+++GO:0071361///cellular response to ethanol+++GO:0090102///cochlea development+++GO:0090103///cochlea morphogenesis" 15396 15396 'Hoxa11' mRNA 0 3 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 1 0 0.659075281 -2.407827175 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001759///organ induction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007501///mesodermal cell fate specification+++GO:0008584///male gonad development+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0010468///regulation of gene expression+++GO:0010720///positive regulation of cell development+++GO:0030326///embryonic limb morphogenesis+++GO:0032330///regulation of chondrocyte differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048589///developmental growth+++GO:0048856///anatomical structure development+++GO:0060065///uterus development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060348///bone development+++GO:0060351///cartilage development involved in endochondral bone morphogenesis" 15399 15399 'Hoxa2' mRNA 25 32 24 0.81 1.03 0.83 0.59 0.67 0.53 0.89 0.596666667 21 23 18 27 20.66666667 0.518009773 -0.393407951 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001709///cell fate determination+++GO:0002076///osteoblast development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007379///segment specification+++GO:0007389///pattern specification process+++GO:0008045///motor neuron axon guidance+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0021568///rhombomere 2 development+++GO:0021569///rhombomere 3 development+++GO:0021658///rhombomere 3 morphogenesis+++GO:0035284///brain segmentation+++GO:0042474///middle ear morphogenesis+++GO:0045165///cell fate commitment+++GO:0045665///negative regulation of neuron differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0060037///pharyngeal system development+++GO:0061061///muscle structure development+++GO:0071300///cellular response to retinoic acid" 15400 15400 'Hoxa3' mRNA 4 3 2 0.09 0.06 0.05 0.02 0.06 0.08 0.066666667 0.053333333 1 3 5 3 3 0.998591786 0.003708267 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0071837///HMG box domain binding" "GO:0001525///angiogenesis+++GO:0001974///blood vessel remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010159///specification of animal organ position+++GO:0010467///gene expression+++GO:0021615///glossopharyngeal nerve morphogenesis+++GO:0030878///thyroid gland development+++GO:0048538///thymus development+++GO:0048645///animal organ formation+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0051216///cartilage development+++GO:0060017///parathyroid gland development" 15401 15401 'Hoxa4' mRNA 0 0 1 0 0 0.04 0 0 0.07 0.013333333 0.023333333 0 0 2 0.333333333 0.666666667 0.863090843 0.890621057 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0048704///embryonic skeletal system morphogenesis" 15402 15402 'Hoxa5' mRNA 3 4 0 0.09 0.12 0 0.05 0.22 0.08 0.07 0.116666667 2 8 3 2.333333333 4.333333333 0.615571341 0.921275988 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0002009///morphogenesis of an epithelium+++GO:0003016///respiratory system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007585///respiratory gaseous exchange+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030324///lung development+++GO:0030878///thyroid gland development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0035264///multicellular organism growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0060435///bronchiole development+++GO:0060439///trachea morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060480///lung goblet cell differentiation+++GO:0060481///lobar bronchus epithelium development+++GO:0060484///lung-associated mesenchyme development+++GO:0060535///trachea cartilage morphogenesis+++GO:0060536///cartilage morphogenesis+++GO:0060574///intestinal epithelial cell maturation+++GO:0060638///mesenchymal-epithelial cell signaling+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060749///mammary gland alveolus development+++GO:0060764///cell-cell signaling involved in mammary gland development" 15404 15404 'Hoxa7' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002686///negative regulation of leukocyte migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045656///negative regulation of monocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048863///stem cell differentiation" 15410 15410 'Hoxb3' mRNA 0 1 1 0 0.02 0.02 0.03 0.05 0.05 0.013333333 0.043333333 3 3 4 0.666666667 3.333333333 0.278253136 2.304069241 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0021546///rhombomere development+++GO:0021615///glossopharyngeal nerve morphogenesis+++GO:0030878///thyroid gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0050767///regulation of neurogenesis+++GO:0051216///cartilage development+++GO:0060216///definitive hemopoiesis+++GO:0060324///face development" 15412 15412 'Hoxb4' mRNA 0 0 1 0 0 0.02 0.09 0.08 0.08 0.006666667 0.083333333 5 4 4 0.333333333 4.333333333 0.082420216 3.582531493 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0030097///hemopoiesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048103///somatic stem cell division+++GO:0048536///spleen development+++GO:0048539///bone marrow development+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0060216///definitive hemopoiesis+++GO:0060218///hematopoietic stem cell differentiation+++GO:2000738///positive regulation of stem cell differentiation" 15423 15423 'Hoxc4' mRNA 0 2 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048562///embryonic organ morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0051216///cartilage development+++GO:1904840///positive regulation of male germ-line stem cell asymmetric division" 15427 15427 'Hoxc9' mRNA 3 0 1 0.06 0 0.02 0.02 0 0.02 0.026666667 0.013333333 1 0 1 1.333333333 0.666666667 0.766839301 -1.019685606 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016235///aggresome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0009954///proximal/distal pattern formation+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development" 15437 15437 'Hoxd8' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048705///skeletal system morphogenesis" 15439 15439 'Hp' mRNA 26 30 28 1.16 1.32 1.33 18.34 15.75 19.57 1.27 17.88666667 471 394 486 28 450.3333333 1.47E-73 3.995280826 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0034366///spherical high-density lipoprotein particle+++GO:0072562///blood microparticle GO:0004252///serine-type endopeptidase activity+++GO:0016209///antioxidant activity+++GO:0030492///hemoglobin binding+++GO:0042802///identical protein binding GO:0001889///liver development+++GO:0002376///immune system process+++GO:0002526///acute inflammatory response+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0007219///Notch signaling pathway+++GO:0009617///response to bacterium+++GO:0010942///positive regulation of cell death+++GO:0031638///zymogen activation+++GO:0042542///response to hydrogen peroxide+++GO:0042742///defense response to bacterium+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0098869///cellular oxidant detoxification+++GO:2000296///negative regulation of hydrogen peroxide catabolic process 15441 15441 'Hp1bp3' mRNA 3288.97 3260 3330 35.02 34.51 38.11 28.03 27.19 26.54 35.88 27.25333333 3001 2828 2769 3292.99 2866 0.002382807 -0.213828795 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0031491///nucleosome binding "GO:0006334///nucleosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042127///regulation of cell proliferation+++GO:0070828///heterochromatin organization+++GO:0071456///cellular response to hypoxia+++GO:0097298///regulation of nucleus size" 15442 15442 'Hpse' mRNA 1185 1346 1192 20.83 23.28 22.22 24.32 27.2 26.01 22.11 25.84333333 1592 1739 1649 1241 1660 1.97E-06 0.409830964 00531///Glycosaminoglycan degradation+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:1904974///heparanase complex "GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030305///heparanase activity+++GO:0045545///syndecan binding" GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0010033///response to organic substance+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0030194///positive regulation of blood coagulation+++GO:0030200///heparan sulfate proteoglycan catabolic process+++GO:0030202///heparin metabolic process+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0042060///wound healing+++GO:0051797///regulation of hair follicle development+++GO:0051798///positive regulation of hair follicle development+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060055///angiogenesis involved in wound healing+++GO:0061028///establishment of endothelial barrier+++GO:0061042///vascular wound healing+++GO:0071806///protein transmembrane transport 15444 15444 'Hpca' mRNA 113 118 118 3.87 4.01 4.02 13.8 14.39 12.38 3.966666667 13.52333333 470 471 398 116.3333333 446.3333333 3.59E-33 1.927474866 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030424///axon+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0032839///dendrite cytoplasm+++GO:0043204///perikaryon+++GO:0044327///dendritic spine head+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007420///brain development+++GO:0010518///positive regulation of phospholipase activity+++GO:0014070///response to organic cyclic compound+++GO:0019722///calcium-mediated signaling+++GO:0031283///negative regulation of guanylate cyclase activity+++GO:0031584///activation of phospholipase D activity+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0048839///inner ear development+++GO:0060041///retina development in camera-type eye+++GO:0071257///cellular response to electrical stimulus+++GO:0071277///cellular response to calcium ion+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901986///response to ketamine+++GO:1902065///response to L-glutamate+++GO:1904009///cellular response to monosodium glutamate+++GO:1904010///response to Aroclor 1254 15445 15445 'Hpd' mRNA 0 3 0 0 0.13 0 0 0 0 0.043333333 0 0 0 0 1 0 0.659075281 -2.407827175 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++01240///Biosynthesis of cofactors GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane "GO:0003868///4-hydroxyphenylpyruvate dioxygenase activity+++GO:0005515///protein binding+++GO:0008127///quercetin 2,3-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016701///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006559///L-phenylalanine catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0009072///aromatic amino acid family metabolic process 15446 15446 'Hpgd' mRNA 206 262 224 6.95 8.71 8.01 2.14 3.28 3.18 7.89 2.866666667 73 109 105 230.6666667 95.66666667 6.67E-09 -1.277462543 05202///Transcriptional misregulation in cancer GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016323///basolateral plasma membrane "GO:0004957///prostaglandin E receptor activity+++GO:0016404///15-hydroxyprostaglandin dehydrogenase (NAD+) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0051287///NAD binding+++GO:0070403///NAD+ binding" GO:0001822///kidney development+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0007567///parturition+++GO:0030728///ovulation+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0043065///positive regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0045786///negative regulation of cell cycle+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0097070///ductus arteriosus closure+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905828///regulation of prostaglandin catabolic process 15450 15450 'Lipc' mRNA 8 5 11 0.27 0.17 0.38 0.5 0.21 0.21 0.273333333 0.306666667 17 7 7 8 10.33333333 0.766483962 0.33626583 00561///Glycerolipid metabolism+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0034364///high-density lipoprotein particle "GO:0004465///lipoprotein lipase activity+++GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008289///lipid binding+++GO:0008970///phospholipase A1 activity+++GO:0016298///lipase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0034185///apolipoprotein binding+++GO:0035478///chylomicron binding+++GO:0042802///identical protein binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102545///phosphatidyl phospholipase B activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006641///triglyceride metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0030301///cholesterol transport+++GO:0034371///chylomicron remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034382///chylomicron remnant clearance+++GO:0034383///low-density lipoprotein particle clearance+++GO:0042632///cholesterol homeostasis+++GO:0046337///phosphatidylethanolamine metabolic process+++GO:0046461///neutral lipid catabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0070328///triglyceride homeostasis+++GO:0097006///regulation of plasma lipoprotein particle levels 15451 15451 'Hpn' mRNA 1215 1232 1170 37.78 37.55 38.39 28.42 27.49 24.72 37.90666667 26.87666667 1050 996 887 1205.666667 977.6666667 7.29E-04 -0.314505103 05203///Viral carcinogenesis GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031965///nuclear membrane+++GO:0043025///neuronal cell body GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070008///serine-type exopeptidase activity GO:0006508///proteolysis+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0010628///positive regulation of gene expression+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010756///positive regulation of plasminogen activation+++GO:0030307///positive regulation of cell growth+++GO:0034769///basement membrane disassembly+++GO:0042632///cholesterol homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043923///positive regulation by host of viral transcription+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060429///epithelium development+++GO:0071805///potassium ion transmembrane transport+++GO:0090103///cochlea morphogenesis+++GO:0097066///response to thyroid hormone+++GO:0097195///pilomotor reflex+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000611///positive regulation of thyroid hormone generation 15452 15452 'Hprt' mRNA 1299 1479 1405 57.88 65.04 66.42 91.62 89.43 94.17 63.11333333 91.74 2361 2248 2347 1394.333333 2318.666667 1.17E-20 0.721102236 00230///Purine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004422///hypoxanthine phosphoribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0052657///guanine phosphoribosyltransferase activity" GO:0001913///T cell mediated cytotoxicity+++GO:0001975///response to amphetamine+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006166///purine ribonucleoside salvage+++GO:0006168///adenine salvage+++GO:0006178///guanine salvage+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0009116///nucleoside metabolic process+++GO:0021756///striatum development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021954///central nervous system neuron development+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0042417///dopamine metabolic process+++GO:0043103///hypoxanthine salvage+++GO:0044209///AMP salvage+++GO:0045964///positive regulation of dopamine metabolic process+++GO:0046038///GMP catabolic process+++GO:0046040///IMP metabolic process+++GO:0046083///adenine metabolic process+++GO:0046100///hypoxanthine metabolic process+++GO:0046651///lymphocyte proliferation+++GO:0048813///dendrite morphogenesis+++GO:0051289///protein homotetramerization 15458 15458 'Hpx' mRNA 7 17 10 0.28 0.67 0.42 0.17 0.39 0.43 0.456666667 0.33 5 11 12 11.33333333 9.333333333 0.797324406 -0.280537227 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0002639///positive regulation of immunoglobulin production+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006879///cellular iron ion homeostasis+++GO:0015886///heme transport+++GO:0020027///hemoglobin metabolic process+++GO:0042168///heme metabolic process+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0051246///regulation of protein metabolic process+++GO:0060332///positive regulation of response to interferon-gamma+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway 15460 15460 'Hr' mRNA 442 391 406 4.29 3.71 4.18 2.11 1.81 1.97 4.06 1.963333333 251 210 226 413 229 3.16E-09 -0.864323328 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0042809///vitamin D receptor binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046966///thyroid hormone receptor binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0033169///histone H3-K9 demethylation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated" 15461 15461 'Hras' mRNA 166 175 126 6.31 6.79 5.3 7.82 8.06 8.64 6.133333333 8.173333333 224 218 238 155.6666667 226.6666667 0.005404931 0.535722914 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04144///Endocytosis+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05132///Salmonella infection+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007569///cell aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010863///positive regulation of phospholipase C activity+++GO:0030335///positive regulation of cell migration+++GO:0032729///positive regulation of interferon-gamma production+++GO:0034260///negative regulation of GTPase activity+++GO:0035900///response to isolation stress+++GO:0042088///T-helper 1 type immune response+++GO:0042832///defense response to protozoan+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045740///positive regulation of DNA replication+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0051726///regulation of cell cycle+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071480///cellular response to gamma radiation+++GO:0090303///positive regulation of wound healing+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0090398///cellular senescence+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1900029///positive regulation of ruffle assembly+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2000630///positive regulation of miRNA metabolic process 15463 15463 'Agfg1' mRNA 487 505 534 3.24 3.32 3.76 3.98 3.77 3.79 3.44 3.846666667 688 636 637 508.6666667 653.6666667 0.003487222 0.347354359 GO:0005634///nucleus+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0001675///acrosome assembly+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007289///spermatid nucleus differentiation+++GO:0030154///cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0045109///intermediate filament organization+++GO:0050790///regulation of catalytic activity 15464 15464 'Hrc' mRNA 2 7 1 0.05 0.16 0.02 0.04 0.06 0.06 0.076666667 0.053333333 2 3 3 3.333333333 2.666666667 0.866217381 -0.305112149 04020///Calcium signaling pathway+++04260///Cardiac muscle contraction GO:0030018///Z disc+++GO:0033017///sarcoplasmic reticulum membrane GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0051117///ATPase binding GO:0002027///regulation of heart rate+++GO:0008016///regulation of heart contraction+++GO:0010460///positive regulation of heart rate+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0045823///positive regulation of heart contraction+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0055074///calcium ion homeostasis+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0090280///positive regulation of calcium ion import+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:1901899///positive regulation of relaxation of cardiac muscle+++GO:1902081///negative regulation of calcium ion import into sarcoplasmic reticulum+++GO:1903169///regulation of calcium ion transmembrane transport+++GO:1990036///calcium ion import into sarcoplasmic reticulum 15465 15465 'Hrh1' mRNA 0 3 0 0 0.05 0 0.01 0.01 0.07 0.016666667 0.03 1 1 5 1 2.333333333 0.646474337 1.249201339 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004969///histamine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051381///histamine binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007268///chemical synaptic transmission+++GO:0007613///memory+++GO:0008542///visual learning+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0043114///regulation of vascular permeability+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0048167///regulation of synaptic plasticity+++GO:0048245///eosinophil chemotaxis+++GO:0048511///rhythmic process+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0071420///cellular response to histamine+++GO:0071421///manganese ion transmembrane transport+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15466 15466 'Hrh2' mRNA 6 14 2 0.08 0.2 0.03 0.38 0.61 0.37 0.103333333 0.453333333 28 39 27 7.333333333 31.33333333 0.001797136 2.105877926 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04971///Gastric acid secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004969///histamine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:1901363///heterocyclic compound binding "GO:0001696///gastric acid secretion+++GO:0001697///histamine-induced gastric acid secretion+++GO:0001698///gastrin-induced gastric acid secretion+++GO:0003382///epithelial cell morphogenesis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007268///chemical synaptic transmission+++GO:0007613///memory+++GO:0008542///visual learning+++GO:0045907///positive regulation of vasoconstriction+++GO:0048167///regulation of synaptic plasticity+++GO:0048565///digestive tract development+++GO:0048732///gland development+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:1900139///negative regulation of arachidonic acid secretion+++GO:1901998///toxin transport" 15467 15467 'Eif2ak1' mRNA 791 844 947 15.71 16.5 19.92 21.8 20.37 19.12 17.37666667 20.43 1262 1149 1073 860.6666667 1161.333333 2.12E-04 0.415387399 04141///Protein processing in endoplasmic reticulum+++05160///Hepatitis C+++05162///Measles+++05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0020037///heme binding+++GO:0042803///protein homodimerization activity GO:0002526///acute inflammatory response+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0008285///negative regulation of cell proliferation+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0010999///regulation of eIF2 alpha phosphorylation by heme+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0030225///macrophage differentiation+++GO:0046501///protoporphyrinogen IX metabolic process+++GO:0046777///protein autophosphorylation+++GO:0046984///regulation of hemoglobin biosynthetic process+++GO:0046986///negative regulation of hemoglobin biosynthetic process+++GO:0055072///iron ion homeostasis+++GO:1990641///response to iron ion starvation 15468 15468 'Prmt2' mRNA 2747 2751 2737 76.17 74.98 80.45 60.26 61.79 57.82 77.2 59.95666667 2504 2507 2327 2745 2446 0.015309109 -0.17889977 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0030331///estrogen receptor binding+++GO:0033142///progesterone receptor binding+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0050681///androgen receptor binding "GO:0001666///response to hypoxia+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032259///methylation+++GO:0033210///leptin-mediated signaling pathway+++GO:0034969///histone arginine methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048588///developmental cell growth+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 15469 15469 'Prmt1' mRNA 811 896 533 36.92 40.07 25.64 34.71 35.01 36.38 34.21 35.36666667 874 859 888 746.6666667 873.6666667 0.131956856 0.224856255 04068///FoxO signaling pathway+++04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0034709///methylosome GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008170///N-methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0008327///methyl-CpG binding+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016275///[cytochrome c]-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0030519///snoRNP binding+++GO:0035241///protein-arginine omega-N monomethyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042802///identical protein binding+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:1904047///S-adenosyl-L-methionine binding "GO:0001701///in utero embryonic development+++GO:0006479///protein methylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0031175///neuron projection development+++GO:0032259///methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0035247///peptidyl-arginine omega-N-methylation+++GO:0043985///histone H4-R3 methylation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0048738///cardiac muscle tissue development+++GO:0051260///protein homooligomerization+++GO:1900745///positive regulation of p38MAPK cascade" 15473 15473 'Rida' mRNA 2097 2000 2077 135.08 127.41 141.96 130.35 135.18 125.36 134.8166667 130.2966667 2320 2345 2156 2058 2273.666667 0.122335078 0.130778106 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005777///peroxisome+++GO:0005829///cytosol "GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0016787///hydrolase activity+++GO:0016892///endoribonuclease activity, producing 3'-phosphomonoesters+++GO:0019239///deaminase activity+++GO:0036041///long-chain fatty acid binding+++GO:0042802///identical protein binding+++GO:0043167///ion binding+++GO:0046914///transition metal ion binding" "GO:0001822///kidney development+++GO:0006402///mRNA catabolic process+++GO:0007420///brain development+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0033993///response to lipid+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0061157///mRNA destabilization+++GO:0070314///G1 to G0 transition+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1901565///organonitrogen compound catabolic process+++GO:1902074///response to salt" 15476 15476 'Hs3st1' mRNA 663 678 606 22.83 23.04 22.16 15.57 13.96 14.98 22.67666667 14.83666667 522 456 484 649 487.3333333 1.38E-04 -0.424465655 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity 15478 15478 'Hs3st3a1' mRNA 181.23 249.86 147.31 2.27 3.13 2.32 0.64 0.45 0.3 2.573333333 0.463333333 54.12 39.48 23.52 192.8 39.04 4.30E-15 -2.320747429 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity 15481 15481 'Hspa8' mRNA 38029 40078 39419 1023.54 1062.51 1125.48 1003.32 1036.87 1015.98 1070.51 1018.723333 42862 43246 42012 39175.33333 42706.66667 0.061118049 0.111812707 03040///Spliceosome+++04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04144///Endocytosis+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation+++04915///Estrogen signaling pathway+++05020///Prion disease+++05134///Legionellosis+++05145///Toxoplasmosis+++05162///Measles+++05417///Lipid and atherosclerosis GO:0000974///Prp19 complex+++GO:0001917///photoreceptor inner segment+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031906///late endosome lumen+++GO:0032279///asymmetric synapse+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0044309///neuron spine+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0098684///photoreceptor ribbon synapse+++GO:0098690///glycinergic synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol+++GO:0099634///postsynaptic specialization membrane+++GO:0101031///chaperone complex+++GO:1990124///messenger ribonucleoprotein complex+++GO:1990836///lysosomal matrix+++GO:1990904///ribonucleoprotein complex "GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0001786///phosphatidylserine binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0030674///protein binding, bridging+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031686///A1 adenosine receptor binding+++GO:0042277///peptide binding+++GO:0043531///ADP binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:1904593///prostaglandin binding+++GO:1990833///clathrin-uncoating ATPase activity" "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0006397///mRNA processing+++GO:0006457///protein folding+++GO:0006606///protein import into nucleus+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0016192///vesicle-mediated transport+++GO:0031647///regulation of protein stability+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0043085///positive regulation of catalytic activity+++GO:0043624///cellular protein complex disassembly+++GO:0044788///modulation by host of viral process+++GO:0044829///positive regulation by host of viral genome replication+++GO:0045862///positive regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046034///ATP metabolic process+++GO:0046777///protein autophosphorylation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0050766///positive regulation of phagocytosis+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051726///regulation of cell cycle+++GO:0061077///chaperone-mediated protein folding+++GO:0061635///regulation of protein complex stability+++GO:0061684///chaperone-mediated autophagy+++GO:0061738///late endosomal microautophagy+++GO:0061740///protein targeting to lysosome involved in chaperone-mediated autophagy+++GO:0072318///clathrin coat disassembly+++GO:0097214///positive regulation of lysosomal membrane permeability+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0099175///regulation of postsynapse organization+++GO:1902904///negative regulation of supramolecular fiber organization+++GO:1904592///positive regulation of protein refolding+++GO:1904764///chaperone-mediated autophagy translocation complex disassembly+++GO:1990832///slow axonal transport" 15482 15482 'Hspa1l' mRNA 34.6 30.33 16.36 0.8 0.69 0.4 1.06 0.28 0.66 0.63 0.666666667 52.57 13.5 31.55 27.09666667 32.54 0.734641318 0.25298958 03040///Spliceosome+++04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04144///Endocytosis+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation+++04915///Estrogen signaling pathway+++05020///Prion disease+++05134///Legionellosis+++05145///Toxoplasmosis+++05162///Measles+++05417///Lipid and atherosclerosis GO:0000228///nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0002199///zona pellucida receptor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016887///ATPase activity+++GO:0030983///mismatched DNA binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0000710///meiotic mismatch repair+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007127///meiosis I+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007292///female gamete generation+++GO:0007339///binding of sperm to zona pellucida+++GO:0016192///vesicle-mediated transport+++GO:0030154///cell differentiation+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051321///meiotic cell cycle+++GO:1903955///positive regulation of protein targeting to mitochondrion 15483 15483 'Hsd11b1' mRNA 2035 2099 1936 90.03 91.84 91.23 92.03 97.54 95.49 91.03333333 95.02 2389 2470 2399 2023.333333 2419.333333 3.89E-04 0.24734923 00140///Steroid hormone biosynthesis+++00980///Metabolism of xenobiotics by cytochrome P450+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell GO:0003845///11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0050661///NADP binding+++GO:0070524///11-beta-hydroxysteroid dehydrogenase (NADP+) activity GO:0006629///lipid metabolic process+++GO:0006704///glucocorticoid biosynthetic process+++GO:0006706///steroid catabolic process+++GO:0006713///glucocorticoid catabolic process+++GO:0008202///steroid metabolic process+++GO:0008212///mineralocorticoid metabolic process+++GO:0030324///lung development+++GO:0043456///regulation of pentose-phosphate shunt 15484 15484 'Hsd11b2' mRNA 6 10 9 0.19 0.31 0.3 0.92 1.22 1.2 0.266666667 1.113333333 34 44 43 8.333333333 40.33333333 3.57E-05 2.264981002 00140///Steroid hormone biosynthesis+++04960///Aldosterone-regulated sodium reabsorption GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0043231///intracellular membrane-bounded organelle GO:0003845///11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0051287///NAD binding GO:0001666///response to hypoxia+++GO:0002017///regulation of blood volume by renal aldosterone+++GO:0007565///female pregnancy+++GO:0008211///glucocorticoid metabolic process+++GO:0032094///response to food+++GO:0032868///response to insulin+++GO:0042493///response to drug+++GO:0048545///response to steroid hormone+++GO:0051384///response to glucocorticoid 15485 15485 'Hsd17b1' mRNA 13 9 18 0.5 0.36 0.71 0.58 0.27 0.36 0.523333333 0.403333333 25 9 16 13.33333333 16.66666667 0.749855753 0.290401362 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0030283///testosterone dehydrogenase [NAD(P)] activity+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0042803///protein homodimerization activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0047045///testosterone 17-beta-dehydrogenase (NADP+) activity+++GO:0050661///NADP binding+++GO:0070401///NADP+ binding+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity+++GO:1903924///estradiol binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0060348///bone development+++GO:0061370///testosterone biosynthetic process+++GO:0071248///cellular response to metal ion 15486 15486 'Hsd17b2' mRNA 8 1 6 0.38 0.05 0.3 0.41 0.65 0.38 0.243333333 0.48 10 15 9 5 11.33333333 0.267928081 1.162795668 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0032526///response to retinoic acid 15488 15488 'Hsd17b4' mRNA 1917 2006 1923 39.54 40.73 42.08 51.46 48.86 48.71 40.78333333 49.67666667 2870 2661 2630 1948.666667 2720.333333 5.54E-12 0.468719696 00120///Primary bile acid biosynthesis+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix "GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016508///long-chain-enoyl-CoA hydratase activity+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0033989///3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0036111///very long-chain fatty-acyl-CoA metabolic process+++GO:0036112///medium-chain fatty-acyl-CoA metabolic process+++GO:0060009///Sertoli cell development 15490 15490 'Hsd17b7' mRNA 7419 7560 7279 87.13 87.78 90.65 10.26 8.59 9.43 88.52 9.426666667 999 822 883 7419.333333 901.3333333 0 -3.054541972 00100///Steroid biosynthesis+++00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000253///3-keto sterol reductase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0005148///prolactin receptor binding+++GO:0016491///oxidoreductase activity+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity+++GO:0102176///cycloeucalenone reductase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008209///androgen metabolic process+++GO:0030154///cell differentiation+++GO:0048568///embryonic organ development+++GO:0048706///embryonic skeletal system development 15492 15492 'Hsd3b1' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0000253///3-keto sterol reductase activity+++GO:0003824///catalytic activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity+++GO:0102176///cycloeucalenone reductase activity+++GO:0102294///cholesterol dehydrogenase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0008152///metabolic process+++GO:0008202///steroid metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0051412///response to corticosterone 15493 15493 'Hsd3b2' mRNA 3 1.16 0 0.08 0.02 0 0 0 0 0.033333333 0 0 0 0 1.386666667 0 0.489543081 -2.838520661 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0003824///catalytic activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0102294///cholesterol dehydrogenase activity" GO:0006694///steroid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0008152///metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0034757///negative regulation of iron ion transport+++GO:0051412///response to corticosterone 15494 15494 'Hsd3b3' mRNA 6.06 5.84 5 0.12 0.13 0.13 0.02 0.02 0 0.126666667 0.013333333 1.89 1.65 0 5.633333333 1.18 0.091444524 -3.012476871 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0003824///catalytic activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0102294///cholesterol dehydrogenase activity" GO:0006694///steroid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0008152///metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0034757///negative regulation of iron ion transport+++GO:0051412///response to corticosterone 15495 15495 'Hsd3b4' mRNA 84.56 126.27 41.06 2.89 4.26 1.49 0 0 0.29 2.88 0.096666667 0 0 9.45 83.96333333 3.15 0.011915574 -4.785107503 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0000253///3-keto sterol reductase activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005496///steroid binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity" GO:0006694///steroid biosynthetic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0035634///response to stilbenoid+++GO:0042448///progesterone metabolic process+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051412///response to corticosterone 15496 15496 'Hsd3b5' mRNA 4.98 2.03 1.83 0.18 0.07 0.07 0 0 0 0.106666667 0 0 0 0 2.946666667 0 0.191408932 -3.659941005 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0000253///3-keto sterol reductase activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity+++GO:0102176///cycloeucalenone reductase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0035634///response to stilbenoid+++GO:0051412///response to corticosterone 15497 15497 'Hsd3b6' mRNA 0 1 1 0 0.03 0.03 0 0 0 0.02 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 00140///Steroid hormone biosynthesis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge "GO:0003824///catalytic activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0004769///steroid delta-isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016853///isomerase activity+++GO:0102294///cholesterol dehydrogenase activity" GO:0006694///steroid biosynthetic process+++GO:0006700///C21-steroid hormone biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0008152///metabolic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0021766///hippocampus development+++GO:0034757///negative regulation of iron ion transport+++GO:0051412///response to corticosterone 15499 15499 'Hsf1' mRNA 1825 1848 1620 47.39 45.95 45 32.84 32.69 29.86 46.11333333 31.79666667 1466 1428 1302 1764.333333 1398.666667 1.25E-05 -0.34503711 04212///Longevity regulating pathway - worm+++05134///Legionellosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0045120///pronucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0097165///nuclear stress granule+++GO:0097431///mitotic spindle pole+++GO:0101031///chaperone complex+++GO:1990904///ribonucleoprotein complex" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0031072///heat shock protein binding+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0046982///protein heterodimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0061770///translation elongation factor binding+++GO:0097677///STAT family protein binding+++GO:0098847///sequence-specific single stranded DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001701///in utero embryonic development+++GO:0001892///embryonic placenta development+++GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006952///defense response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007143///female meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0007584///response to nutrient+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009299///mRNA transcription+++GO:0009408///response to heat+++GO:0010243///response to organonitrogen compound+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0031333///negative regulation of protein complex assembly+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033574///response to testosterone+++GO:0034605///cellular response to heat+++GO:0034620///cellular response to unfolded protein+++GO:0034622///cellular protein-containing complex assembly+++GO:0035690///cellular response to drug+++GO:0035865///cellular response to potassium ion+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043200///response to amino acid+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051028///mRNA transport+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060136///embryonic process involved in female pregnancy+++GO:0061408///positive regulation of transcription from RNA polymerase II promoter in response to heat stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071392///cellular response to estradiol stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071478///cellular response to radiation+++GO:0071480///cellular response to gamma radiation+++GO:0072738///cellular response to diamide+++GO:0090084///negative regulation of inclusion body assembly+++GO:0090231///regulation of spindle checkpoint+++GO:0090261///positive regulation of inclusion body assembly+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900034///regulation of cellular response to heat+++GO:1900365///positive regulation of mRNA polyadenylation+++GO:1901215///negative regulation of neuron death+++GO:1901652///response to peptide+++GO:1902512///positive regulation of apoptotic DNA fragmentation+++GO:1903936///cellular response to sodium arsenite+++GO:1904385///cellular response to angiotensin+++GO:1904528///positive regulation of microtubule binding+++GO:1904843///cellular response to nitroglycerin+++GO:1904845///cellular response to L-glutamine+++GO:1990910///response to hypobaric hypoxia+++GO:1990911///response to psychosocial stress+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining" 15500 15500 'Hsf2' mRNA 479 476 473 9.4 8.87 9.97 9.15 9.22 10.11 9.413333333 9.493333333 522 517 561 476 533.3333333 0.257551735 0.152094746 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II" 15502 15502 'Dnaja1' mRNA 4159 4607 4362 66.87 72.87 74.43 78.33 81.04 75.69 71.39 78.35333333 5606 5665 5247 4376 5506 1.79E-06 0.319253161 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0030957///Tat protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0055131///C3HC4-type RING finger domain binding "GO:0006457///protein folding+++GO:0007283///spermatogenesis+++GO:0009408///response to heat+++GO:0030317///flagellated sperm motility+++GO:0030521///androgen receptor signaling pathway+++GO:0031397///negative regulation of protein ubiquitination+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0051223///regulation of protein transport+++GO:0070585///protein localization to mitochondrion+++GO:1901998///toxin transport+++GO:1903748///negative regulation of establishment of protein localization to mitochondrion+++GO:1905259///negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway" 15504 15504 'Dnajb3' mRNA 30 28 31 1.88 1.73 2.06 0.76 1.34 0.96 1.89 1.02 14 24 17 29.66666667 18.33333333 0.213949329 -0.704656316 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0005515///protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0008150///biological_process+++GO:0061077///chaperone-mediated protein folding 15505 15505 'Hsph1' mRNA 3102.75 3225.55 3114.06 48.33 49.46 51.46 19.5 19.68 20.68 49.75 19.95333333 1439.6 1415 1478.1 3147.453333 1444.233333 6.29E-63 -1.135995708 04141///Protein processing in endoplasmic reticulum GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0043014///alpha-tubulin binding GO:0006986///response to unfolded protein+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051135///positive regulation of NK T cell activation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1903748///negative regulation of establishment of protein localization to mitochondrion+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903753///negative regulation of p38MAPK cascade+++GO:2001234///negative regulation of apoptotic signaling pathway 15507 15507 'Hspb1' mRNA 2744 2656 2566 199.55 191.2 198.01 383.83 402.75 390.24 196.2533333 392.2733333 6047 6182 5939 2655.333333 6056 2.28E-90 1.178316695 04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++05146///Amoebiasis GO:0000502///proteasome complex+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031430///M band+++GO:0031674///I band+++GO:0043204///perikaryon+++GO:0043292///contractile fiber+++GO:0045202///synapse+++GO:0097512///cardiac myofibril+++GO:0098839///postsynaptic density membrane+++GO:1904115///axon cytoplasm GO:0005080///protein kinase C binding+++GO:0008426///protein kinase C inhibitor activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043130///ubiquitin binding+++GO:0044183///protein binding involved in protein folding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0001932///regulation of protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006986///response to unfolded protein+++GO:0009615///response to virus+++GO:0010976///positive regulation of neuron projection development+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0061077///chaperone-mediated protein folding+++GO:0099641///anterograde axonal protein transport+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:2001028///positive regulation of endothelial cell chemotaxis+++GO:2001234///negative regulation of apoptotic signaling pathway 15510 15510 'Hspd1' mRNA 2998 3206 2998 71.34 75.2 75.8 92.49 82.98 82.88 74.11333333 86.11666667 4451 3900 3862 3067.333333 4071 4.93E-09 0.395517481 03018///RNA degradation+++04212///Longevity regulating pathway - worm+++04940///Type I diabetes mellitus+++05134///Legionellosis+++05152///Tuberculosis+++05417///Lipid and atherosclerosis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005769///early endosome+++GO:0005782///peroxisomal matrix+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030061///mitochondrial crista+++GO:0030135///coated vesicle+++GO:0030141///secretory granule+++GO:0031985///Golgi cisterna+++GO:0032991///protein-containing complex+++GO:0042588///zymogen granule+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0046696///lipopolysaccharide receptor complex+++GO:0070062///extracellular exosome+++GO:0097225///sperm midpiece GO:0000166///nucleotide binding+++GO:0001530///lipopolysaccharide binding+++GO:0002039///p53 binding+++GO:0003725///double-stranded RNA binding+++GO:0005524///ATP binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034185///apolipoprotein binding+++GO:0034186///apolipoprotein A-I binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding+++GO:0140030///modification-dependent protein binding GO:0001666///response to hypoxia+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0002842///positive regulation of T cell mediated immune response to tumor cell+++GO:0002931///response to ischemia+++GO:0006457///protein folding+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006986///response to unfolded protein+++GO:0008637///apoptotic mitochondrial changes+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0010033///response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0032496///response to lipopolysaccharide+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033198///response to ATP+++GO:0034514///mitochondrial unfolded protein response+++GO:0034605///cellular response to heat+++GO:0042026///protein refolding+++GO:0042100///B cell proliferation+++GO:0042110///T cell activation+++GO:0042113///B cell activation+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043032///positive regulation of macrophage activation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0044406///adhesion of symbiont to host+++GO:0045041///protein import into mitochondrial intermembrane space+++GO:0048291///isotype switching to IgG isotypes+++GO:0050729///positive regulation of inflammatory response+++GO:0050821///protein stabilization+++GO:0050870///positive regulation of T cell activation+++GO:0051384///response to glucocorticoid+++GO:0051702///interaction with symbiont+++GO:0071866///negative regulation of apoptotic process in bone marrow+++GO:0098761///cellular response to interleukin-7+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process 15511 15511 'Hspa1b' mRNA 260.8 288.07 304.68 5.12 5.57 6.35 10.5 7.31 7.42 5.68 8.41 614.78 417.92 420.57 284.5166667 484.4233333 8.40E-06 0.749635996 03040///Spliceosome+++04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04144///Endocytosis+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation+++04915///Estrogen signaling pathway+++05020///Prion disease+++05134///Legionellosis+++05145///Toxoplasmosis+++05162///Measles+++05417///Lipid and atherosclerosis GO:0002199///zona pellucida receptor complex+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016234///inclusion body+++GO:0016235///aggresome+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042826///histone deacetylase binding+++GO:0044183///protein binding involved in protein folding+++GO:0047485///protein N-terminus binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding+++GO:0055131///C3HC4-type RING finger domain binding GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0007339///binding of sperm to zona pellucida+++GO:0009408///response to heat+++GO:0016192///vesicle-mediated transport+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0060548///negative regulation of cell death+++GO:0090063///positive regulation of microtubule nucleation+++GO:1901673///regulation of mitotic spindle assembly 15512 15512 'Hspa2' mRNA 3603 3461 3346 77.96 73.72 76.82 28.21 28.89 27.08 76.16666667 28.06 1499.23 1500 1393 3470 1464.076667 4.63E-78 -1.256524919 03040///Spliceosome+++04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04144///Endocytosis+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation+++04915///Estrogen signaling pathway+++05020///Prion disease+++05134///Legionellosis+++05145///Toxoplasmosis+++05162///Measles+++05417///Lipid and atherosclerosis GO:0000795///synaptonemal complex+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0036128///CatSper complex+++GO:0043209///myelin sheath+++GO:0072687///meiotic spindle GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0048156///tau protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding+++GO:0051861///glycolipid binding+++GO:0097718///disordered domain specific binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016192///vesicle-mediated transport+++GO:0030154///cell differentiation+++GO:0032781///positive regulation of ATPase activity+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0070194///synaptonemal complex disassembly+++GO:0090084///negative regulation of inclusion body assembly+++GO:1901896///positive regulation of calcium-transporting ATPase activity 15516 15516 'Hsp90ab1' mRNA 32719 33120 32233 726.96 724.47 759.71 601.17 583.9 610.41 737.0466667 598.4933333 31122 29518 30594 32690.66667 30411.33333 0.023504664 -0.11682311 04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04612///Antigen processing and presentation+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04659///Th17 cell differentiation+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++05132///Salmonella infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016234///inclusion body+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0032991///protein-containing complex+++GO:0034751///aryl hydrocarbon receptor complex+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:1990565///HSP90-CDC37 chaperone complex+++GO:1990913///sperm head plasma membrane+++GO:1990917///ooplasm GO:0000166///nucleotide binding+++GO:0002134///UTP binding+++GO:0002135///CTP binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016887///ATPase activity+++GO:0017098///sulfonylurea receptor binding+++GO:0019887///protein kinase regulator activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0030911///TPR domain binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032564///dATP binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043008///ATP-dependent protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0044325///ion channel binding+++GO:0046983///protein dimerization activity+++GO:0048156///tau protein binding+++GO:0051082///unfolded protein binding+++GO:0070182///DNA polymerase binding+++GO:0097718///disordered domain specific binding+++GO:1901363///heterocyclic compound binding+++GO:1990226///histone methyltransferase binding GO:0001890///placenta development+++GO:0006457///protein folding+++GO:0007004///telomere maintenance via telomerase+++GO:0009651///response to salt stress+++GO:0010033///response to organic substance+++GO:0019062///virion attachment to host cell+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030010///establishment of cell polarity+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031396///regulation of protein ubiquitination+++GO:0032092///positive regulation of protein binding+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0032880///regulation of protein localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034605///cellular response to heat+++GO:0042220///response to cocaine+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045793///positive regulation of cell size+++GO:0048675///axon extension+++GO:0050821///protein stabilization+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051248///negative regulation of protein metabolic process+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051973///positive regulation of telomerase activity+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071353///cellular response to interleukin-4+++GO:0071407///cellular response to organic cyclic compound+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0097435///supramolecular fiber organization+++GO:1901389///negative regulation of transforming growth factor beta activation+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1903660///negative regulation of complement-dependent cytotoxicity+++GO:1903827///regulation of cellular protein localization+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:1905323///telomerase holoenzyme complex assembly+++GO:2000010///positive regulation of protein localization to cell surface 15519 15519 'Hsp90aa1' mRNA 19450 19587 19615 376.27 372.93 402.52 249.8 247.95 252.97 383.9066667 250.24 14856 14401 14567 19550.66667 14608 1.91E-16 -0.433525931 04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04612///Antigen processing and presentation+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04659///Th17 cell differentiation+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++05132///Salmonella infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0002135///CTP binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0030911///TPR domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032564///dATP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0044183///protein binding involved in protein folding+++GO:0048156///tau protein binding+++GO:0051020///GTPase binding+++GO:0051082///unfolded protein binding+++GO:0070182///DNA polymerase binding+++GO:0097110///scaffold protein binding+++GO:0097718///disordered domain specific binding+++GO:1990782///protein tyrosine kinase binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006457///protein folding+++GO:0006809///nitric oxide biosynthetic process+++GO:0006986///response to unfolded protein+++GO:0007004///telomere maintenance via telomerase+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030010///establishment of cell polarity+++GO:0031396///regulation of protein ubiquitination+++GO:0032273///positive regulation of protein polymerization+++GO:0032728///positive regulation of interferon-beta production+++GO:0032880///regulation of protein localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034605///cellular response to heat+++GO:0042026///protein refolding+++GO:0042981///regulation of apoptotic process+++GO:0045040///protein import into mitochondrial outer membrane+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045585///positive regulation of cytotoxic T cell differentiation+++GO:0046677///response to antibiotic+++GO:0048675///axon extension+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051973///positive regulation of telomerase activity+++GO:0098586///cellular response to virus+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1903827///regulation of cellular protein localization+++GO:1905323///telomerase holoenzyme complex assembly 15525 15525 'Hspa4' mRNA 1156 1221 1084 13.35 13.87 13.28 22.83 23.09 22.84 13.5 22.92 2275 2248 2205 1153.666667 2242.666667 4.42E-41 0.948674704 04530///Tight junction+++04612///Antigen processing and presentation+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0070062///extracellular exosome GO:0000166///nucleotide binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0033613///activating transcription factor binding+++GO:0044877///protein-containing complex binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0001933///negative regulation of protein phosphorylation+++GO:0009408///response to heat+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0032092///positive regulation of protein binding+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0045040///protein import into mitochondrial outer membrane+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0060548///negative regulation of cell death 15526 15526 'Hspa9' mRNA 4316 4490 4733 77.83 79.68 90.54 78.62 81.86 76.91 82.68333333 79.13 5016 5101 4752 4513 4956.333333 0.138954909 0.120891907 03018///RNA degradation+++04212///Longevity regulating pathway - worm+++05152///Tuberculosis GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017134///fibroblast growth factor binding+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding GO:0006457///protein folding+++GO:0006611///protein export from nucleus+++GO:0016226///iron-sulfur cluster assembly+++GO:0030218///erythrocyte differentiation+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0045646///regulation of erythrocyte differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0046777///protein autophosphorylation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0060548///negative regulation of cell death+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1903707///negative regulation of hemopoiesis 15528 15528 'Hspe1' mRNA 947 906 906 85.16 80.8 86.46 116.56 121.58 119.28 84.14 119.14 1483 1506 1465 919.6666667 1484.666667 2.24E-16 0.679162428 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0051085///chaperone cofactor-dependent protein refolding 15529 15529 'Sdc2' mRNA 2660 2738 2564 43.81 44.37 44.8 34.24 31.49 32.81 44.32666667 32.84666667 2392 2149 2220 2654 2253.666667 2.36E-04 -0.248027821 04361///Axon regeneration+++04514///Cell adhesion molecules+++05144///Malaria+++05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005796///Golgi lumen+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding GO:0007399///nervous system development+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0048813///dendrite morphogenesis+++GO:0048814///regulation of dendrite morphogenesis 15530 15530 'Hspg2' mRNA 1608 1545 1159 5.88 5.55 4.68 7.36 6.19 7.28 5.37 6.943333333 2285 1856 2164 1437.333333 2101.666667 7.04E-08 0.540812792 04512///ECM-receptor interaction+++05161///Hepatitis B+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005796///Golgi lumen+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001958///endochondral ossification+++GO:0002062///chondrocyte differentiation+++GO:0006898///receptor-mediated endocytosis+++GO:0007420///brain development+++GO:0008104///protein localization+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0030198///extracellular matrix organization+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048738///cardiac muscle tissue development+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0060548///negative regulation of cell death+++GO:1905907///negative regulation of amyloid fibril formation 15531 15531 'Ndst1' mRNA 1469.02 1235.81 1582.31 7.95 6.61 9.59 12.01 10.09 11.4 8.05 11.16666667 2497.43 2115.26 2272.33 1429.046667 2295.006667 2.66E-10 0.6649639 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008146///sulfotransferase activity+++GO:0015016///[heparan sulfate]-glucosamine N-sulfotransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0102140///heparan sulfate N-deacetylase activity "GO:0000271///polysaccharide biosynthetic process+++GO:0003279///cardiac septum development+++GO:0006476///protein deacetylation+++GO:0006477///protein sulfation+++GO:0006954///inflammatory response+++GO:0007507///heart development+++GO:0007585///respiratory gaseous exchange+++GO:0008152///metabolic process+++GO:0008283///cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009790///embryo development+++GO:0009887///animal organ morphogenesis+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0030203///glycosaminoglycan metabolic process+++GO:0030210///heparin biosynthetic process+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0035904///aorta development+++GO:0043410///positive regulation of MAPK cascade+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0060976///coronary vasculature development" 15547 15547 'Trmt2a' mRNA 1259.77 1533.92 1481.91 26.26 31.52 31.48 26.9 27 28.01 29.75333333 27.30333333 1521.62 1468.68 1554.97 1425.2 1515.09 0.528624376 0.074876443 GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0006396///RNA processing+++GO:0032259///methylation 15551 15551 'Htr1b' mRNA 16 29 24 0.18 0.32 0.29 0.31 0.18 0.24 0.263333333 0.243333333 31 18 24 23 24.33333333 0.925316235 0.065093655 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse+++04742///Taste transduction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0044305///calyx of Held+++GO:0098666///G protein-coupled serotonin receptor complex+++GO:0099056///integral component of presynaptic membrane+++GO:0099154///serotonergic synapse GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels+++GO:1901363///heterocyclic compound binding "GO:0002031///G protein-coupled receptor internalization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007610///behavior+++GO:0007631///feeding behavior+++GO:0009636///response to toxic substance+++GO:0014053///negative regulation of gamma-aminobutyric acid secretion+++GO:0014059///regulation of dopamine secretion+++GO:0014063///negative regulation of serotonin secretion+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0035690///cellular response to drug+++GO:0042220///response to cocaine+++GO:0042310///vasoconstriction+++GO:0042756///drinking behavior+++GO:0045471///response to ethanol+++GO:0046849///bone remodeling+++GO:0050795///regulation of behavior+++GO:0051385///response to mineralocorticoid+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0071312///cellular response to alkaloid+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071502///cellular response to temperature stimulus+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000300///regulation of synaptic vesicle exocytosis" 15552 15552 'Htr1d' mRNA 120.23 99.08 104.39 0.85 0.69 0.79 0.42 0.57 0.33 0.776666667 0.44 67.45 90.83 52.45 107.9 70.24333333 0.035902505 -0.638046431 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0009636///response to toxic substance+++GO:0014827///intestine smooth muscle contraction+++GO:0040012///regulation of locomotion+++GO:0042310///vasoconstriction+++GO:0050795///regulation of behavior" 15557 15557 'Htr1f' mRNA 0 3 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 1 0 0.659075281 -2.407827175 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15558 15558 'Htr2a' mRNA 6 5 20 0.11 0.09 0.4 0.16 0.3 0.15 0.2 0.203333333 10 18 9 10.33333333 12.33333333 0.857142038 0.217857467 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04540///Gap junction+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0070852///cell body fiber+++GO:0098666///G protein-coupled serotonin receptor complex+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0001587///Gq/11-coupled serotonin receptor activity+++GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051378///serotonin binding+++GO:0071886///1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding" "GO:0001659///temperature homeostasis+++GO:0006874///cellular calcium ion homeostasis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007208///phospholipase C-activating serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007568///aging+++GO:0007610///behavior+++GO:0007613///memory+++GO:0008219///cell death+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0010513///positive regulation of phosphatidylinositol biosynthetic process+++GO:0014059///regulation of dopamine secretion+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014824///artery smooth muscle contraction+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0019233///sensory perception of pain+++GO:0030431///sleep+++GO:0033674///positive regulation of kinase activity+++GO:0042493///response to drug+++GO:0043267///negative regulation of potassium ion transport+++GO:0043406///positive regulation of MAP kinase activity+++GO:0044380///protein localization to cytoskeleton+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045821///positive regulation of glycolytic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0048148///behavioral response to cocaine+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:2000300///regulation of synaptic vesicle exocytosis" 15559 15559 'Htr2b' mRNA 18.84 18.49 31.34 0.14 0.12 0.27 1.77 1.64 1.58 0.176666667 1.663333333 100.52 93.64 84.64 22.89 92.93333333 2.22E-08 2.025960648 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04540///Gap junction+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098666///G protein-coupled serotonin receptor complex GO:0001587///Gq/11-coupled serotonin receptor activity+++GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0005096///GTPase activator activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0001755///neural crest cell migration+++GO:0001819///positive regulation of cytokine production+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002031///G protein-coupled receptor internalization+++GO:0003007///heart morphogenesis+++GO:0003300///cardiac muscle hypertrophy+++GO:0006874///cellular calcium ion homeostasis+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007208///phospholipase C-activating serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007507///heart development+++GO:0007610///behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0010507///negative regulation of autophagy+++GO:0010513///positive regulation of phosphatidylinositol biosynthetic process+++GO:0014033///neural crest cell differentiation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014827///intestine smooth muscle contraction+++GO:0016310///phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0034220///ion transmembrane transport+++GO:0042310///vasoconstriction+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0048598///embryonic morphogenesis+++GO:0050795///regulation of behavior+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051781///positive regulation of cell division+++GO:0060548///negative regulation of cell death+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070528///protein kinase C signaling+++GO:0071418///cellular response to amine stimulus+++GO:0071502///cellular response to temperature stimulus+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:1904015///cellular response to serotonin" 15560 15560 'Htr2c' mRNA 5 3 1 0.06 0.03 0.01 0 0 0 0.033333333 0 0 0 0 3 0 0.110162608 -4.018408732 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04540///Gap junction+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0098666///G protein-coupled serotonin receptor complex "GO:0001587///Gq/11-coupled serotonin receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042802///identical protein binding+++GO:0051378///serotonin binding+++GO:0071886///1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding" "GO:0001662///behavioral fear response+++GO:0006874///cellular calcium ion homeostasis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007208///phospholipase C-activating serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007610///behavior+++GO:0007626///locomotory behavior+++GO:0007631///feeding behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0010513///positive regulation of phosphatidylinositol biosynthetic process+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0014057///positive regulation of acetylcholine secretion, neurotransmission+++GO:0019934///cGMP-mediated signaling+++GO:0031583///phospholipase D-activating G protein-coupled receptor signaling pathway+++GO:0031644///regulation of neurological system process+++GO:0032098///regulation of appetite+++GO:0035095///behavioral response to nicotine+++GO:0040013///negative regulation of locomotion+++GO:0042493///response to drug+++GO:0043397///regulation of corticotropin-releasing hormone secretion+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0045963///negative regulation of dopamine metabolic process+++GO:0048016///inositol phosphate-mediated signaling+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051930///regulation of sensory perception of pain+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15561 15561 'Htr3a' mRNA 2 1 0 0.05 0.03 0 0 0 0.02 0.026666667 0.006666667 0 0 1 1 0.333333333 0.734648197 -1.462234613 04726///Serotonergic synapse+++04742///Taste transduction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032154///cleavage furrow+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:1904602///serotonin-activated cation-selective channel complex GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0022850///serotonin-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0042802///identical protein binding+++GO:0051378///serotonin binding GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007210///serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0034220///ion transmembrane transport+++GO:0042220///response to cocaine+++GO:0042391///regulation of membrane potential+++GO:0045471///response to ethanol+++GO:0050877///nervous system process+++GO:0071363///cellular response to growth factor stimulus 15562 15562 'Htr4' mRNA 4.06 0 4 0.03 0 0.05 0.01 0.02 0.03 0.026666667 0.02 2.3 3 5.57 2.686666667 3.623333333 0.876147748 0.294635714 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0005515///protein binding+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0032098///regulation of appetite+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15563 15563 'Htr5a' mRNA 9 2 3 0.11 0.02 0.03 0.01 0 0.01 0.053333333 0.006666667 1 0 1 4.666666667 0.666666667 0.144802492 -2.817966713 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043204///perikaryon+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007420///brain development+++GO:0019933///cAMP-mediated signaling+++GO:0021766///hippocampus development+++GO:0032355///response to estradiol+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15564 15564 'Htr5b' mRNA 12 18 14 0.34 0.49 0.4 0.02 0.05 0.05 0.41 0.04 1 2 2 14.66666667 1.666666667 0.002742173 -3.144759055 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0001664///G protein-coupled receptor binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0051378///serotonin binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007198///adenylate cyclase-inhibiting serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15565 15565 'Htr6' mRNA 3 0 2 0.05 0 0.03 0.01 0.09 0.01 0.026666667 0.036666667 1 7 1 1.666666667 3 0.7188336 0.840081244 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04726///Serotonergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0005515///protein binding+++GO:0030594///neurotransmitter receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007268///chemical synaptic transmission+++GO:0007612///learning+++GO:0014050///negative regulation of glutamate secretion+++GO:0014053///negative regulation of gamma-aminobutyric acid secretion+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0014058///negative regulation of acetylcholine secretion, neurotransmission+++GO:0021795///cerebral cortex cell migration+++GO:0032008///positive regulation of TOR signaling+++GO:0033603///positive regulation of dopamine secretion+++GO:0060291///long-term synaptic potentiation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 15566 15566 'Htr7' mRNA 29 25 23 0.48 0.44 0.4 0.57 0.39 0.53 0.44 0.496666667 37 25 37 25.66666667 33 0.530402137 0.35058179 04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04361///Axon regeneration+++04726///Serotonergic synapse GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity "GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007192///adenylate cyclase-activating serotonin receptor signaling pathway+++GO:0007210///serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0010976///positive regulation of neuron projection development+++GO:0014063///negative regulation of serotonin secretion+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0042310///vasoconstriction+++GO:0042322///negative regulation of circadian sleep/wake cycle, REM sleep+++GO:0048266///behavioral response to pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051412///response to corticosterone+++GO:0060073///micturition+++GO:0060291///long-term synaptic potentiation+++GO:0071542///dopaminergic neuron differentiation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:2000300///regulation of synaptic vesicle exocytosis" 15567 15567 'Slc6a4' mRNA 2 1 0 0.04 0.02 0 0.47 0.54 0.45 0.02 0.486666667 27 30 25 1 27.33333333 7.53E-06 4.768947582 04721///Synaptic vesicle cycle+++04726///Serotonergic synapse GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016234///inclusion body+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0097060///synaptic membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099154///serotonergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0002039///p53 binding+++GO:0005102///signaling receptor binding+++GO:0005326///neurotransmitter transporter activity+++GO:0005335///serotonin:sodium symporter activity+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0008504///monoamine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0017075///syntaxin-1 binding+++GO:0019811///cocaine binding+++GO:0019900///kinase binding+++GO:0031072///heat shock protein binding+++GO:0034452///dynactin binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0045505///dynein intermediate chain binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding+++GO:0050809///diazepam binding+++GO:0050998///nitric-oxide synthase binding+++GO:0051015///actin filament binding+++GO:0051378///serotonin binding "GO:0000050///urea cycle+++GO:0000052///citrulline metabolic process+++GO:0000132///establishment of mitotic spindle orientation+++GO:0001666///response to hypoxia+++GO:0006836///neurotransmitter transport+++GO:0006837///serotonin transport+++GO:0006839///mitochondrial transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007005///mitochondrion organization+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007212///dopamine receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007369///gastrulation+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007569///cell aging+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0008088///axo-dendritic transport+++GO:0008306///associative learning+++GO:0008340///determination of adult lifespan+++GO:0008542///visual learning+++GO:0009636///response to toxic substance+++GO:0009653///anatomical structure morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0014064///positive regulation of serotonin secretion+++GO:0015844///monoamine transport+++GO:0016197///endosomal transport+++GO:0019244///lactate biosynthetic process from pyruvate+++GO:0019805///quinolinate biosynthetic process+++GO:0021756///striatum development+++GO:0021941///negative regulation of cerebellar granule cell precursor proliferation+++GO:0021988///olfactory lobe development+++GO:0021990///neural plate formation+++GO:0022008///neurogenesis+++GO:0030072///peptide hormone secretion+++GO:0030073///insulin secretion+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0031648///protein destabilization+++GO:0032227///negative regulation of synaptic transmission, dopaminergic+++GO:0032355///response to estradiol+++GO:0034504///protein localization to nucleus+++GO:0035176///social behavior+++GO:0035725///sodium ion transmembrane transport+++GO:0042297///vocal learning+++GO:0042310///vasoconstriction+++GO:0042445///hormone metabolic process+++GO:0042493///response to drug+++GO:0042713///sperm ejaculation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0045665///negative regulation of neuron differentiation+++GO:0045724///positive regulation of cilium assembly+++GO:0045787///positive regulation of cell cycle+++GO:0046621///negative regulation of organ growth+++GO:0047496///vesicle transport along microtubule+++GO:0048167///regulation of synaptic plasticity+++GO:0048341///paraxial mesoderm formation+++GO:0048666///neuron development+++GO:0048854///brain morphogenesis+++GO:0051028///mRNA transport+++GO:0051592///response to calcium ion+++GO:0051610///serotonin uptake+++GO:0055072///iron ion homeostasis+++GO:0055085///transmembrane transport+++GO:0071300///cellular response to retinoic acid+++GO:0071310///cellular response to organic substance+++GO:0071321///cellular response to cGMP+++GO:0071539///protein localization to centrosome+++GO:0090067///regulation of thalamus size+++GO:0098810///neurotransmitter reuptake+++GO:0099111///microtubule-based transport+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1900180///regulation of protein localization to nucleus+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:1904504///positive regulation of lipophagy+++GO:1904580///regulation of intracellular mRNA localization+++GO:1905289///regulation of CAMKK-AMPK signaling cascade+++GO:1905337///positive regulation of aggrephagy+++GO:1905505///positive regulation of motile cilium assembly+++GO:2000117///negative regulation of cysteine-type endopeptidase activity+++GO:2000479///regulation of cAMP-dependent protein kinase activity+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 15568 15568 'Elavl1' mRNA 2163 2113 2010 19.02 18.27 18.73 22.89 21.52 21.67 18.67333333 22.02666667 2999 2755 2749 2095.333333 2834.333333 9.36E-11 0.423920027 04152///AMPK signaling pathway+++04657///IL-17 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0031410///cytoplasmic vesicle+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0035198///miRNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042803///protein homodimerization activity GO:0006417///regulation of translation+++GO:0006606///protein import into nucleus+++GO:0016441///posttranscriptional gene silencing+++GO:0045727///positive regulation of translation+++GO:0048255///mRNA stabilization+++GO:0051260///protein homooligomerization+++GO:0060965///negative regulation of gene silencing by miRNA+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:2000036///regulation of stem cell population maintenance 15569 15569 'Elavl2' mRNA 2 2 0 0.01 0.03 0 0 0 0 0.013333333 0 0 0 0 1.333333333 0 0.487988649 -2.833701114 GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:1990830///cellular response to leukemia inhibitory factor 15571 15571 'Elavl3' mRNA 0 4 1 0 0.04 0.01 0.04 0 0.02 0.016666667 0.02 4 0 2 1.666666667 2 0.924011351 0.253669189 GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation 15572 15572 'Elavl4' mRNA 2 6 7 0.03 0.09 0.1 0.15 0.06 0.04 0.073333333 0.083333333 13 5 3 5 7 0.750146649 0.45248096 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042788///polysomal ribosome+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0045182///translation regulator activity+++GO:0097158///pre-mRNA intronic pyrimidine-rich binding "GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0007568///aging+++GO:0007612///learning+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0008380///RNA splicing+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030182///neuron differentiation+++GO:0031099///regeneration+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042220///response to cocaine+++GO:0043488///regulation of mRNA stability+++GO:0048813///dendrite morphogenesis+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0099547///regulation of translation at synapse, modulating synaptic transmission+++GO:1900006///positive regulation of dendrite development+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization+++GO:1990090///cellular response to nerve growth factor stimulus" 15574 15574 'Hus1' mRNA 474.57 523.75 563.94 6.12 6.6 7.53 4.94 4.63 4.56 6.75 4.71 463.39 420.82 411.56 520.7533333 431.9233333 0.042403742 -0.285559021 04218///Cellular senescence GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030896///checkpoint clamp complex+++GO:0035861///site of double-strand break GO:0000077///DNA damage checkpoint+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001932///regulation of protein phosphorylation+++GO:0006289///nucleotide-excision repair+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0031573///intra-S DNA damage checkpoint+++GO:0033314///mitotic DNA replication checkpoint+++GO:0044778///meiotic DNA integrity checkpoint+++GO:0071479///cellular response to ionizing radiation 15586 15586 'Hyal1' mRNA 1378.4 1501.13 1202.45 26.87 28.8 24.83 21.56 22.81 21.98 26.83333333 22.11666667 1288.56 1329.86 1271.69 1360.66 1296.703333 0.453568102 -0.077775864 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle+++GO:0036117///hyaluranon cable "GO:0001618///virus receptor activity+++GO:0003824///catalytic activity+++GO:0004415///hyalurononglucosaminidase activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0050501///hyaluronan synthase activity" GO:0000302///response to reactive oxygen species+++GO:0005975///carbohydrate metabolic process+++GO:0006954///inflammatory response+++GO:0008152///metabolic process+++GO:0009615///response to virus+++GO:0010634///positive regulation of epithelial cell migration+++GO:0030212///hyaluronan metabolic process+++GO:0030213///hyaluronan biosynthetic process+++GO:0030214///hyaluronan catabolic process+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045766///positive regulation of angiogenesis+++GO:0045785///positive regulation of cell adhesion+++GO:0045927///positive regulation of growth+++GO:0046677///response to antibiotic+++GO:0046718///viral entry into host cell+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071467///cellular response to pH+++GO:0071493///cellular response to UV-B+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1900106///positive regulation of hyaluranon cable assembly 15587 15587 'Hyal2' mRNA 562 577 596 17.04 17.19 19.16 21.99 22.29 23.01 17.79666667 22.43 825 822 840 578.3333333 829 1.44E-06 0.506371955 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030139///endocytic vesicle+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0001618///virus receptor activity+++GO:0003713///transcription coactivator activity+++GO:0003824///catalytic activity+++GO:0004415///hyalurononglucosaminidase activity+++GO:0005540///hyaluronic acid binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019899///enzyme binding+++GO:0030294///receptor signaling protein tyrosine kinase inhibitor activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0033906///hyaluronoglucuronidase activity+++GO:0050431///transforming growth factor beta binding" GO:0000302///response to reactive oxygen species+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process+++GO:0008152///metabolic process+++GO:0009615///response to virus+++GO:0010259///multicellular organism aging+++GO:0010764///negative regulation of fibroblast migration+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0019087///transformation of host cell by virus+++GO:0030214///hyaluronan catabolic process+++GO:0030308///negative regulation of cell growth+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0035810///positive regulation of urine volume+++GO:0042117///monocyte activation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043407///negative regulation of MAP kinase activity+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046677///response to antibiotic+++GO:0046718///viral entry into host cell+++GO:0048705///skeletal system morphogenesis+++GO:0050729///positive regulation of inflammatory response+++GO:0051216///cartilage development+++GO:0051607///defense response to virus+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0070295///renal water absorption+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071493///cellular response to UV-B+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 15891 15891 'Ibsp' mRNA 21 40 35 0.61 1.15 1.08 0.56 0.47 0.47 0.946666667 0.5 22 18 18 32 19.33333333 0.18153761 -0.742317667 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031982///vesicle GO:0005178///integrin binding GO:0001503///ossification+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030282///bone mineralization+++GO:0031214///biomineral tissue development+++GO:0045785///positive regulation of cell adhesion+++GO:0071363///cellular response to growth factor stimulus 15893 15893 'Ica1' mRNA 1119 1093 1084 33.74 32.85 35.78 6.08 6.24 6.66 34.12333333 6.326666667 229 231 238 1098.666667 232.6666667 4.02E-96 -2.251478493 04940///Type I diabetes mellitus GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0140090///membrane curvature sensor activity GO:0006836///neurotransmitter transport+++GO:0043254///regulation of protein complex assembly+++GO:0046928///regulation of neurotransmitter secretion+++GO:0050796///regulation of insulin secretion+++GO:0051049///regulation of transport 15894 15894 'Icam1' mRNA 240 264 244 5.18 5.6 5.58 28.93 28.01 27.4 5.453333333 28.11333333 1543 1459 1415 249.3333333 1472.333333 1.49E-143 2.550310777 04064///NF-kappa B signaling pathway+++04514///Cell adhesion molecules+++04650///Natural killer cell mediated cytotoxicity+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04933///AGE-RAGE signaling pathway in diabetic complications+++05143///African trypanosomiasis+++05144///Malaria+++05150///Staphylococcus aureus infection+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05323///Rheumatoid arthritis+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0001772///immunological synapse+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome GO:0005178///integrin binding+++GO:0044877///protein-containing complex binding GO:0002291///T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0002457///T cell antigen processing and presentation+++GO:0002693///positive regulation of cellular extravasation+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0022614///membrane to membrane docking+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033627///cell adhesion mediated by integrin+++GO:0043547///positive regulation of GTPase activity+++GO:0044406///adhesion of symbiont to host+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050900///leukocyte migration+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051926///negative regulation of calcium ion transport+++GO:0061028///establishment of endothelial barrier+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071333///cellular response to glucose stimulus+++GO:0072683///T cell extravasation+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0097368///establishment of Sertoli cell barrier+++GO:0098609///cell-cell adhesion+++GO:1900027///regulation of ruffle assembly+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904646///cellular response to amyloid-beta+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000352///negative regulation of endothelial cell apoptotic process 15896 15896 'Icam2' mRNA 61 54 82 3.29 2.8 4.59 12.74 11.64 11.55 3.56 11.97666667 286 246 244 65.66666667 258.6666667 1.22E-18 1.957996388 04514///Cell adhesion molecules+++04650///Natural killer cell mediated cytotoxicity GO:0001931///uropod+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032154///cleavage furrow+++GO:0042995///cell projection+++GO:0071944///cell periphery GO:0005178///integrin binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 15898 15898 'Icam5' mRNA 21 24 15 0.39 0.4 0.29 0.45 0.75 0.51 0.36 0.57 28 46 31 20 35 0.128079411 0.806583544 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding+++GO:0005515///protein binding GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 15900 15900 'Irf8' mRNA 163 168 213 3.16 3.2 4.38 37.47 39.01 38.3 3.58 38.26 2228 2264 2203 181.3333333 2231.666667 1.45E-231 3.606353474 05133///Pertussis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002273///plasmacytoid dendritic cell differentiation+++GO:0002314///germinal center B cell differentiation+++GO:0002316///follicular B cell differentiation+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006909///phagocytosis+++GO:0006914///autophagy+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0030099///myeloid cell differentiation+++GO:0032479///regulation of type I interferon production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0097028///dendritic cell differentiation" 15901 15901 'Id1' mRNA 1062 1073 959 72.65 72.79 69.39 42.73 44.13 41.5 71.61 42.78666667 718 728 679 1031.333333 708.3333333 1.95E-09 -0.552008695 04015///Rap1 signaling pathway+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0046983///protein dimerization activity+++GO:0047485///protein N-terminus binding+++GO:0070628///proteasome binding+++GO:0140110///transcription regulator activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001886///endothelial cell morphogenesis+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007623///circadian rhythm+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0031648///protein destabilization+++GO:0032091///negative regulation of protein binding+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032922///circadian regulation of gene expression+++GO:0032963///collagen metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043408///regulation of MAPK cascade+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045765///regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046677///response to antibiotic+++GO:0048511///rhythmic process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0060425///lung morphogenesis+++GO:0060426///lung vasculature development+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901342///regulation of vasculature development" 15902 15902 'Id2' mRNA 1030 982 1042 49.18 46.29 52.79 61.23 69.09 66.54 49.42 65.62 1472 1620 1547 1018 1546.333333 9.24E-11 0.590696515 04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0140110///transcription regulator activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0001779///natural killer cell differentiation+++GO:0001966///thigmotaxis+++GO:0002521///leukocyte differentiation+++GO:0003149///membranous septum morphogenesis+++GO:0003166///bundle of His development+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0009649///entrainment of circadian clock+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0019216///regulation of lipid metabolic process+++GO:0021772///olfactory bulb development+++GO:0030154///cell differentiation+++GO:0032922///circadian regulation of gene expression+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043353///enucleate erythrocyte differentiation+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045475///locomotor rhythm+++GO:0045578///negative regulation of B cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045777///positive regulation of blood pressure+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048468///cell development+++GO:0048469///cell maturation+++GO:0048511///rhythmic process+++GO:0048535///lymph node development+++GO:0048541///Peyer's patch development+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048663///neuron fate commitment+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0060612///adipose tissue development+++GO:0060749///mammary gland alveolus development+++GO:0061030///epithelial cell differentiation involved in mammary gland alveolus development+++GO:0061031///endodermal digestive tract morphogenesis+++GO:0071285///cellular response to lithium ion+++GO:0090398///cellular senescence+++GO:1904797///negative regulation of core promoter binding+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:2000177///regulation of neural precursor cell proliferation" 15903 15903 'Id3' mRNA 3392 3460 3244 230.35 232.47 233.76 269.42 269.11 264 232.1933333 267.51 4547 4426 4305 3365.333333 4426 2.09E-11 0.383830479 04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0046983///protein dimerization activity+++GO:0140110///transcription regulator activity+++GO:1901707///leptomycin B binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0006275///regulation of DNA replication+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0007623///circadian rhythm+++GO:0009611///response to wounding+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030855///epithelial cell differentiation+++GO:0030903///notochord development+++GO:0032922///circadian regulation of gene expression+++GO:0042476///odontogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0072750///cellular response to leptomycin B" 15904 15904 'Id4' mRNA 1923 2018 1467 26.21 27.05 21.21 4.42 4.41 4.65 24.82333333 4.493333333 373 364 380 1802.666667 372.3333333 1.33E-105 -2.281033773 04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0140110///transcription regulator activity "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0007405///neuroblast proliferation+++GO:0007420///brain development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0021766///hippocampus development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0032922///circadian regulation of gene expression+++GO:0034613///cellular protein localization+++GO:0045444///fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0060512///prostate gland morphogenesis+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060741///prostate gland stromal morphogenesis+++GO:0061682///seminal vesicle morphogenesis" 15925 15925 'Ide' mRNA 1863.43 1819.88 1722.4 19.09 18.37 18.81 17.19 16.98 17.11 18.75666667 17.09333333 1942.61 1878.19 1868.16 1801.903333 1896.32 0.462530842 0.062619333 05010///Alzheimer disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0031597///cytosolic proteasome complex+++GO:0070062///extracellular exosome GO:0000166///nucleotide binding+++GO:0001540///amyloid-beta binding+++GO:0003824///catalytic activity+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017046///peptide hormone binding+++GO:0031626///beta-endorphin binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043559///insulin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0140036///ubiquitin-dependent protein binding GO:0006508///proteolysis+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0008340///determination of adult lifespan+++GO:0010815///bradykinin catabolic process+++GO:0010992///ubiquitin recycling+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0030163///protein catabolic process+++GO:0032092///positive regulation of protein binding+++GO:0042447///hormone catabolic process+++GO:0043171///peptide catabolic process+++GO:0044257///cellular protein catabolic process+++GO:0045861///negative regulation of proteolysis+++GO:0050435///amyloid-beta metabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0097242///amyloid-beta clearance+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1901142///insulin metabolic process+++GO:1901143///insulin catabolic process+++GO:1903715///regulation of aerobic respiration 15926 15926 'Idh1' mRNA 2083 2119 2102 51.68 51.8 55.32 79.39 71.91 76.73 52.93333333 76.01 3677 3252 3440 2101.333333 3456.333333 1.51E-25 0.704438375 00020///Citrate cycle (TCA cycle)+++00480///Glutathione metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids+++04146///Peroxisome+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005829///cytosol "GO:0000287///magnesium ion binding+++GO:0004448///isocitrate dehydrogenase activity+++GO:0004450///isocitrate dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050661///NADP binding+++GO:0051287///NAD binding" GO:0006097///glyoxylate cycle+++GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006739///NADP metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006979///response to oxidative stress+++GO:0008585///female gonad development+++GO:0014070///response to organic cyclic compound+++GO:0048545///response to steroid hormone+++GO:0060696///regulation of phospholipid catabolic process+++GO:0071071///regulation of phospholipid biosynthetic process 15929 15929 'Idh3g' mRNA 3563 3742 3679 161.42 167.39 176.99 155.53 152.78 155.54 168.6 154.6166667 3939 3773 3809 3661.333333 3840.333333 0.472546526 0.055924123 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005730///nucleolus+++GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004449///isocitrate dehydrogenase (NAD+) activity+++GO:0005524///ATP binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0046872///metal ion binding+++GO:0051287///NAD binding" GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006734///NADH metabolic process+++GO:0045926///negative regulation of growth 15930 15930 'Ido1' mRNA 5 1 0 0.2 0.04 0 0.14 0.1 0.07 0.08 0.103333333 4 3 2 2 3 0.791504937 0.593301392 00380///Tryptophan metabolism+++01240///Biosynthesis of cofactors+++05143///African trypanosomiasis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030485///smooth muscle contractile fiber+++GO:0032421///stereocilium bundle "GO:0004833///tryptophan 2,3-dioxygenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016597///amino acid binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0033754///indoleamine 2,3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0002376///immune system process+++GO:0002534///cytokine production involved in inflammatory response+++GO:0002666///positive regulation of T cell tolerance induction+++GO:0002678///positive regulation of chronic inflammatory response+++GO:0002830///positive regulation of type 2 immune response+++GO:0006569///tryptophan catabolic process+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0019441///tryptophan catabolic process to kynurenine+++GO:0032496///response to lipopolysaccharide+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0033555///multicellular organismal response to stress+++GO:0034276///kynurenic acid biosynthetic process+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0036269///swimming behavior+++GO:0042130///negative regulation of T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0070234///positive regulation of T cell apoptotic process 15931 15931 'Ids' mRNA 418 447 427 4.54 4.84 4.94 5.82 4.81 5.68 4.773333333 5.436666667 608 492 578 430.6666667 559.3333333 0.004610599 0.363721119 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005764///lysosome GO:0003824///catalytic activity+++GO:0004423///iduronate-2-sulfatase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006027///glycosaminoglycan catabolic process 15932 15932 'Idua' mRNA 1143.13 1105.95 1213.98 16.68 15.96 18.07 15.56 15.65 14.86 16.90333333 15.35666667 1228 1158.94 1137.91 1154.353333 1174.95 0.933133791 0.010706248 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0030135///coated vesicle "GO:0003940///L-iduronidase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0005102///signaling receptor binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0000902///cell morphogenesis+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process+++GO:0007040///lysosome organization+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008152///metabolic process+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0030198///extracellular matrix organization+++GO:0030209///dermatan sulfate catabolic process+++GO:0030211///heparin catabolic process+++GO:0035108///limb morphogenesis+++GO:0045780///positive regulation of bone resorption+++GO:0048705///skeletal system morphogenesis+++GO:0048878///chemical homeostasis+++GO:0060348///bone development+++GO:0061037///negative regulation of cartilage development+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0120158///positive regulation of collagen catabolic process+++GO:1990079///cartilage homeostasis 15936 15936 'Ier2' mRNA 808 821 798 31.3 31.37 32.8 48.26 58.72 51.1 31.82333333 52.69333333 1431 1699 1466 809 1532 7.81E-21 0.91085469 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0030182///neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048870///cell motility+++GO:0071774///response to fibroblast growth factor 15937 15937 'Ier3' mRNA 903 972 853 51.91 55.22 52.03 191.85 191.79 201.84 53.05333333 195.16 3828 3731 3893 909.3333333 3817.333333 2.63E-206 2.059452554 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0001562///response to protozoan+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006282///regulation of DNA repair+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0043066///negative regulation of apoptotic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045820///negative regulation of glycolytic process+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0050728///negative regulation of inflammatory response+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2001020///regulation of response to DNA damage stimulus 15939 15939 'Ier5' mRNA 101 101 33 1.69 1.66 0.58 1.94 1.5 2.38 1.31 1.94 134 101 159 78.33333333 131.3333333 0.03674387 0.751447269 GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0042802///identical protein binding GO:0034605///cellular response to heat+++GO:0042127///regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1900036///positive regulation of cellular response to heat 15944 15944 'Irgm1' mRNA 4374.73 4611.45 4478.89 117.08 121.7 127.37 154.49 153.26 155.58 122.05 154.4433333 6677 6494 6512.03 4488.356667 6561.01 1.28E-20 0.535416384 05145///Toxoplasmosis GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0001891///phagocytic cup+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0044754///autolysosome+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0050700///CARD domain binding+++GO:0051434///BH3 domain binding GO:0000045///autophagosome assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0006952///defense response+++GO:0009617///response to bacterium+++GO:0010508///positive regulation of autophagy+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0031648///protein destabilization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035458///cellular response to interferon-beta+++GO:0042742///defense response to bacterium+++GO:0043254///regulation of protein complex assembly+++GO:0045087///innate immune response+++GO:0050821///protein stabilization+++GO:0050829///defense response to Gram-negative bacterium+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0061635///regulation of protein complex stability+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:0098586///cellular response to virus+++GO:1901098///positive regulation of autophagosome maturation 15945 15945 'Cxcl10' mRNA 87 76 52 4.94 4.26 3.13 36.04 35.24 37.59 4.11 36.29 728 694 734 71.66666667 718.6666667 4.23E-96 3.318686583 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04620///Toll-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05160///Hepatitis C+++05164///Influenza A+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0042056///chemoattractant activity+++GO:0045236///CXCR chemokine receptor binding+++GO:0048248///CXCR3 chemokine receptor binding GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0010818///T cell chemotaxis+++GO:0010819///regulation of T cell chemotaxis+++GO:0016525///negative regulation of angiogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0042118///endothelial cell activation+++GO:0042127///regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0045662///negative regulation of myoblast differentiation+++GO:0050918///positive chemotaxis+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051607///defense response to virus+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0098586///cellular response to virus+++GO:1901509///regulation of endothelial tube morphogenesis+++GO:1901740///negative regulation of myoblast fusion+++GO:2000406///positive regulation of T cell migration 15950 15950 'Ifi203' mRNA 112.42 127 148.83 1.38 1.41 1.85 9.86 9.45 9.68 1.546666667 9.663333333 922.12 855.53 880.33 129.4166667 885.9933333 5.34E-91 2.764098448 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009617///response to bacterium+++GO:0030308///negative regulation of cell growth+++GO:0030889///negative regulation of B cell proliferation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0040008///regulation of growth+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway 15951 15951 'Ifi204' mRNA 99.07 88.82 87.99 2.42 2.12 2.25 30.54 29.69 26.53 2.263333333 28.92 1449.58 1371.3 1220.18 91.96 1347.02 1.58E-189 3.870540739 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0042405///nuclear inclusion body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002218///activation of innate immune response+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009617///response to bacterium+++GO:0030224///monocyte differentiation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042149///cellular response to glucose starvation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043392///negative regulation of DNA binding+++GO:0045071///negative regulation of viral genome replication+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045824///negative regulation of innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:0051607///defense response to virus+++GO:0071479///cellular response to ionizing radiation+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:2000117///negative regulation of cysteine-type endopeptidase activity" 15953 15953 'Ifi47' mRNA 267 276 319 8.96 9.04 11.35 44.53 47.53 43.13 9.783333333 45.06333333 1528 1593 1434 287.3333333 1518.333333 3.07E-103 2.387118202 04668///TNF signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 15957 15957 'Ifit1' mRNA 2176.54 2249.79 2237.11 45.76 46.56 49.9 56.19 56.78 56.92 47.40666667 56.63 3074.37 3033.81 3015.06 2221.146667 3041.08 7.60E-11 0.440686507 05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0005515///protein binding GO:0002376///immune system process+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 15958 15958 'Ifit2' mRNA 650 609 598 8.99 8.4 8.8 21.84 23.15 21.72 8.73 22.23666667 1769 1818 1702 619 1763 6.24E-70 1.498904113 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0003723///RNA binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0009615///response to virus+++GO:0032091///negative regulation of protein binding+++GO:0035457///cellular response to interferon-alpha+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 15959 15959 'Ifit3' mRNA 2514.92 2728.49 2777.6 71.87 76.76 84.21 114.42 118.99 118.63 77.61333333 117.3466667 4606.92 4677.3 4615.57 2673.67 4633.263333 9.24E-28 0.779872782 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0035634///response to stilbenoid+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 15975 15975 'Ifnar1' mRNA 1831.18 1953.33 2067.32 13.79 14.45 16.51 20.22 20.88 19.57 14.91666667 20.22333333 3093.65 3120.74 2900.09 1950.61 3038.16 1.65E-14 0.62473346 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004637///phosphoribosylamine-glycine ligase activity+++GO:0004896///cytokine receptor activity+++GO:0004904///interferon receptor activity+++GO:0004905///type I interferon receptor activity+++GO:0019962///type I interferon binding "GO:0019221///cytokine-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032606///type I interferon production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035457///cellular response to interferon-alpha+++GO:0042110///T cell activation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:1901857///positive regulation of cellular respiration" 15976 15976 'Ifnar2' mRNA 1653.03 1660.98 1587.81 73.29 69.89 68.58 128.99 123.03 128.75 70.58666667 126.9233333 3530.38 3306.46 3418.67 1633.94 3418.503333 3.60E-63 1.053419817 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0004905///type I interferon receptor activity+++GO:0019901///protein kinase binding+++GO:0019962///type I interferon binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 15978 15978 'Ifng' mRNA 0 1 1 0 0.05 0.05 0.09 0.32 0.18 0.033333333 0.196666667 2 7 4 0.666666667 4.333333333 0.168596225 2.692174107 03050///Proteasome+++04060///Cytokine-cytokine receptor interaction+++04066///HIF-1 signaling pathway+++04217///Necroptosis+++04350///TGF-beta signaling pathway+++04380///Osteoclast differentiation+++04612///Antigen processing and presentation+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05160///Hepatitis C+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009897///external side of plasma membrane+++GO:0043005///neuron projection+++GO:0043204///perikaryon GO:0005125///cytokine activity+++GO:0005133///interferon-gamma receptor binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001774///microglial cell activation+++GO:0001781///neutrophil apoptotic process+++GO:0001819///positive regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002026///regulation of the force of heart contraction+++GO:0002250///adaptive immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0002302///CD8-positive, alpha-beta T cell differentiation involved in immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0006925///inflammatory cell apoptotic process+++GO:0006955///immune response+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010835///regulation of protein ADP-ribosylation+++GO:0019882///antigen processing and presentation+++GO:0030225///macrophage differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031334///positive regulation of protein complex assembly+++GO:0031642///negative regulation of myelination+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032747///positive regulation of interleukin-23 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032834///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0040008///regulation of growth+++GO:0042102///positive regulation of T cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0043065///positive regulation of apoptotic process+++GO:0044794///positive regulation by host of viral process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045821///positive regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048143///astrocyte activation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050691///regulation of defense response to virus by host+++GO:0050729///positive regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050769///positive regulation of neurogenesis+++GO:0050776///regulation of immune response+++GO:0050796///regulation of insulin secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050852///T cell receptor signaling pathway+++GO:0050954///sensory perception of mechanical stimulus+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051173///positive regulation of nitrogen compound metabolic process+++GO:0051607///defense response to virus+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0051726///regulation of cell cycle+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0060251///regulation of glial cell proliferation+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060550///positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0060552///positive regulation of fructose 1,6-bisphosphate metabolic process+++GO:0060557///positive regulation of vitamin D biosynthetic process+++GO:0060559///positive regulation of calcidiol 1-monooxygenase activity+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071351///cellular response to interleukin-18+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072125///negative regulation of glomerular mesangial cell proliferation+++GO:0090312///positive regulation of protein deacetylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0098908///regulation of neuronal action potential+++GO:0150076///neuroinflammatory response+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1901216///positive regulation of neuron death+++GO:1901857///positive regulation of cellular respiration+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902948///negative regulation of tau-protein kinase activity+++GO:1904440///positive regulation of ferrous iron import across plasma membrane+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:1904798///positive regulation of core promoter binding+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:2000345///regulation of hepatocyte proliferation" 15979 15979 'Ifngr1' mRNA 1131 1129 1163 30.31 29.81 33.07 56.83 56.54 56.71 31.06333333 56.69333333 2438 2368 2355 1141 2387 8.52E-45 1.05171943 04060///Cytokine-cytokine receptor interaction+++04066///HIF-1 signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031982///vesicle GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding GO:0001774///microglial cell activation+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0048143///astrocyte activation+++GO:0051607///defense response to virus+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1904783///positive regulation of NMDA glutamate receptor activity 15980 15980 'Ifngr2' mRNA 720 719 741 19.37 19.05 21.15 57.62 59.19 55.08 19.85666667 57.29666667 2463 2470 2279 726.6666667 2404 1.52E-98 1.713222771 04060///Cytokine-cytokine receptor interaction+++04066///HIF-1 signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity GO:0001774///microglial cell activation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0051607///defense response to virus+++GO:1904783///positive regulation of NMDA glutamate receptor activity 15982 15982 'Ifrd1' mRNA 823 950 811 26.09 29.68 27.28 40.52 39.31 39.33 27.68333333 39.72 1469 1391 1380 861.3333333 1413.333333 2.36E-16 0.703942156 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0014706///striated muscle tissue development+++GO:0030154///cell differentiation+++GO:0030517///negative regulation of axon extension+++GO:0042692///muscle cell differentiation+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048671///negative regulation of collateral sprouting+++GO:0051091///positive regulation of DNA-binding transcription factor activity 15983 15983 'Ifrd2' mRNA 344.12 354.73 261.44 9.91 10.06 7.98 11.37 11.27 10.73 9.316666667 11.12333333 453.96 439.39 414.61 320.0966667 435.9866667 0.002319936 0.438730866 GO:0003674///molecular_function GO:0008150///biological_process 15985 15985 'Cd79b' mRNA 15 8 9 0.74 0.41 0.47 1.25 0.98 0.58 0.54 0.936666667 29 22 13 10.66666667 21.33333333 0.166609092 0.986765524 04662///B cell receptor signaling pathway GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019815///B cell receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0030183///B cell differentiation+++GO:0050853///B cell receptor signaling pathway 16000 16000 'Igf1' mRNA 586 588 516 4.41 4.34 4.1 8.97 8.93 9.01 4.283333333 8.97 1379 1343 1344 563.3333333 1355.333333 2.41E-47 1.256680785 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05224///Breast cancer+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy" GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031091///platelet alpha granule+++GO:0035867///alphav-beta3 integrin-IGF-1-IGF1R complex+++GO:0042567///insulin-like growth factor ternary complex+++GO:0043025///neuronal cell body+++GO:0070382///exocytic vesicle GO:0005158///insulin receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005179///hormone activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0043539///protein serine/threonine kinase activator activity "GO:0000187///activation of MAPK activity+++GO:0001649///osteoblast differentiation+++GO:0001775///cell activation+++GO:0001932///regulation of protein phosphorylation+++GO:0001974///blood vessel remodeling+++GO:0002683///negative regulation of immune system process+++GO:0006417///regulation of translation+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007608///sensory perception of smell+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009408///response to heat+++GO:0010001///glial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0010560///positive regulation of glycoprotein biosynthetic process+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0014896///muscle hypertrophy+++GO:0014904///myotube cell development+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0021940///positive regulation of cerebellar granule cell precursor proliferation+++GO:0030104///water homeostasis+++GO:0030166///proteoglycan biosynthetic process+++GO:0030307///positive regulation of cell growth+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030879///mammary gland development+++GO:0031017///exocrine pancreas development+++GO:0031643///positive regulation of myelination+++GO:0032148///activation of protein kinase B activity+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032878///regulation of establishment or maintenance of cell polarity+++GO:0033143///regulation of intracellular steroid hormone receptor signaling pathway+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0035264///multicellular organism growth+++GO:0035630///bone mineralization involved in bone maturation+++GO:0040014///regulation of multicellular organism growth+++GO:0042060///wound healing+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0043491///protein kinase B signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0045445///myoblast differentiation+++GO:0045471///response to ethanol+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045821///positive regulation of glycolytic process+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048286///lung alveolus development+++GO:0048468///cell development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048839///inner ear development+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0050974///detection of mechanical stimulus involved in sensory perception+++GO:0051246///regulation of protein metabolic process+++GO:0051450///myoblast proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051924///regulation of calcium ion transport+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060283///negative regulation of oocyte development+++GO:0060426///lung vasculature development+++GO:0060463///lung lobe morphogenesis+++GO:0060509///type I pneumocyte differentiation+++GO:0060510///type II pneumocyte differentiation+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0060736///prostate gland growth+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060741///prostate gland stromal morphogenesis+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0071333///cellular response to glucose stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090031///positive regulation of steroid hormone biosynthetic process+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1900142///negative regulation of oligodendrocyte apoptotic process+++GO:1901215///negative regulation of neuron death+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1904075///positive regulation of trophectodermal cell proliferation+++GO:1904193///negative regulation of cholangiocyte apoptotic process+++GO:1904646///cellular response to amyloid-beta+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905460///negative regulation of vascular associated smooth muscle cell apoptotic process+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2000288///positive regulation of myoblast proliferation+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 16001 16001 'Igf1r' mRNA 2423.68 2481.49 2232.32 11.17 11.26 10.89 6.83 5.55 6.06 11.10666667 6.146666667 1712.12 1360.74 1465.95 2379.163333 1512.936667 1.21E-16 -0.665680045 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04144///Endocytosis+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04510///Focal adhesion+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04730///Long-term depression+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005899///insulin receptor complex+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0035867///alphav-beta3 integrin-IGF-1-IGF1R complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:1902911///protein kinase complex GO:0000166///nucleotide binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005009///insulin-activated receptor activity+++GO:0005010///insulin-like growth factor-activated receptor activity+++GO:0005158///insulin receptor binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031994///insulin-like growth factor I binding+++GO:0042802///identical protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043559///insulin binding+++GO:0043560///insulin receptor substrate binding+++GO:0044877///protein-containing complex binding "GO:0006468///protein phosphorylation+++GO:0006955///immune response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008544///epidermis development+++GO:0009887///animal organ morphogenesis+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021549///cerebellum development+++GO:0030010///establishment of cell polarity+++GO:0030238///male sex determination+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0030879///mammary gland development+++GO:0031017///exocrine pancreas development+++GO:0031175///neuron projection development+++GO:0032467///positive regulation of cytokinesis+++GO:0032869///cellular response to insulin stimulus+++GO:0033674///positive regulation of kinase activity+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042593///glucose homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043243///positive regulation of protein complex disassembly+++GO:0043409///negative regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0044849///estrous cycle+++GO:0045056///transcytosis+++GO:0045471///response to ethanol+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046328///regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048639///positive regulation of developmental growth+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048680///positive regulation of axon regeneration+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051446///positive regulation of meiotic cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0071333///cellular response to glucose stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090031///positive regulation of steroid hormone biosynthetic process+++GO:0097062///dendritic spine maintenance+++GO:0097242///amyloid-beta clearance+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1902065///response to L-glutamate+++GO:1903944///negative regulation of hepatocyte apoptotic process+++GO:1904193///negative regulation of cholangiocyte apoptotic process+++GO:1904646///cellular response to amyloid-beta+++GO:1990314///cellular response to insulin-like growth factor stimulus" 16002 16002 'Igf2' mRNA 1511 1407 1007 39.89 35.14 28.51 51.83 52.19 50.39 34.51333333 51.47 2260 2149 2131 1308.333333 2180 6.90E-13 0.731754474 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05225///Hepatocellular carcinoma GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005158///insulin receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0048018///receptor ligand activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001892///embryonic placenta development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009887///animal organ morphogenesis+++GO:0014070///response to organic cyclic compound+++GO:0031017///exocrine pancreas development+++GO:0031056///regulation of histone modification+++GO:0035094///response to nicotine+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042493///response to drug+++GO:0043085///positive regulation of catalytic activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0046622///positive regulation of organ growth+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051146///striated muscle cell differentiation+++GO:0051147///regulation of muscle cell differentiation+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0051781///positive regulation of cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060669///embryonic placenta morphogenesis+++GO:0060720///spongiotrophoblast cell proliferation+++GO:0090031///positive regulation of steroid hormone biosynthetic process+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000467///positive regulation of glycogen (starch) synthase activity 16004 16004 'Igf2r' mRNA 879 842 804 5.17 4.86 5.01 7.53 6.68 6.97 5.013333333 7.06 1476 1280 1324 841.6666667 1360 4.05E-15 0.680012931 04142///Lysosome+++04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030118///clathrin coat+++GO:0030139///endocytic vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0001965///G-protein alpha-subunit binding+++GO:0001972///retinoic acid binding+++GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0005537///mannose binding+++GO:0019899///enzyme binding+++GO:0031995///insulin-like growth factor II binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding+++GO:1905394///retromer complex binding GO:0001889///liver development+++GO:0007041///lysosomal transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0009791///post-embryonic development+++GO:0031100///animal organ regeneration+++GO:0032526///response to retinoic acid+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0044794///positive regulation by host of viral process+++GO:1904772///response to tetrachloromethane 16005 16005 'Igfals' mRNA 100 94 68 2.63 2.45 1.91 1.36 1.51 1.95 2.33 1.606666667 59 64 82 87.33333333 68.33333333 0.287095801 -0.358186414 "04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0042567///insulin-like growth factor ternary complex GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0008201///heparin binding+++GO:0048495///Roundabout binding GO:0007155///cell adhesion+++GO:0007411///axon guidance+++GO:0050919///negative chemotaxis 16007 16007 'Ccn1' mRNA 1824 1847 1775 51.13 51 52.78 70.44 71.5 69.25 51.63666667 70.39666667 2889 2863 2749 1815.333333 2833.666667 1.24E-21 0.630713601 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding+++GO:0050840///extracellular matrix binding "GO:0001649///osteoblast differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002041///intussusceptive angiogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003278///apoptotic process involved in heart morphogenesis+++GO:0003281///ventricular septum development+++GO:0006935///chemotaxis+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0010518///positive regulation of phospholipase activity+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044319///wound healing, spreading of cells+++GO:0045597///positive regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060413///atrial septum morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060591///chondroblast differentiation+++GO:0060710///chorio-allantoic fusion+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061036///positive regulation of cartilage development+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0072593///reactive oxygen species metabolic process+++GO:0098609///cell-cell adhesion+++GO:2000304///positive regulation of ceramide biosynthetic process" 16008 16008 'Igfbp2' mRNA 4210 4220 4251 225.26 223.1 243.49 740.41 768.99 746.59 230.6166667 751.9966667 15744 15830 15309 4227 15627.66667 7.19E-248 1.873715586 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0005520///insulin-like growth factor binding+++GO:0019838///growth factor binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding GO:0007165///signal transduction+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009612///response to mechanical stimulus+++GO:0010226///response to lithium ion+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032870///cellular response to hormone stimulus+++GO:0040008///regulation of growth+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042493///response to drug+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0043627///response to estrogen+++GO:0048545///response to steroid hormone+++GO:0051384///response to glucocorticoid 16009 16009 'Igfbp3' mRNA 2371 2333 2429 54.08 52.35 58.75 12.06 13.43 14.16 55.06 13.21666667 609 661 691 2377.666667 653.6666667 6.87E-101 -1.875612948 "04115///p53 signaling pathway+++04218///Cellular senescence+++04935///Growth hormone synthesis, secretion and action+++05202///Transcriptional misregulation in cancer" GO:0000792///heterochromatin+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0031091///platelet alpha granule+++GO:0042567///insulin-like growth factor ternary complex+++GO:0042568///insulin-like growth factor binary complex GO:0001968///fibronectin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008160///protein tyrosine phosphatase activator activity+++GO:0019838///growth factor binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding GO:0001558///regulation of cell growth+++GO:0001649///osteoblast differentiation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010906///regulation of glucose metabolic process+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0040008///regulation of growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0044342///type B pancreatic cell proliferation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:1902512///positive regulation of apoptotic DNA fragmentation+++GO:2000844///negative regulation of testosterone secretion 16010 16010 'Igfbp4' mRNA 3965 3840 3557 107.01 101.99 101.95 325.11 295.94 320 103.65 313.6833333 13840 12308 13205 3787.333333 13117.66667 3.74E-242 1.780796544 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0019838///growth factor binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding GO:0001558///regulation of cell growth+++GO:0006954///inflammatory response+++GO:0010906///regulation of glucose metabolic process+++GO:0040008///regulation of growth+++GO:0043410///positive regulation of MAPK cascade+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0044342///type B pancreatic cell proliferation 16011 16011 'Igfbp5' mRNA 27224 27431 19631 246.97 244.65 188.9 117.35 105.55 106.99 226.84 109.9633333 14894 13089 13154 24762 13712.33333 4.26E-26 -0.858325826 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016942///insulin-like growth factor binding protein complex+++GO:0042567///insulin-like growth factor ternary complex GO:0001968///fibronectin binding+++GO:0005520///insulin-like growth factor binding+++GO:0019838///growth factor binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding GO:0001558///regulation of cell growth+++GO:0001649///osteoblast differentiation+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0017148///negative regulation of translation+++GO:0030336///negative regulation of cell migration+++GO:0031069///hair follicle morphogenesis+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042593///glucose homeostasis+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0044342///type B pancreatic cell proliferation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045926///negative regulation of growth+++GO:0048286///lung alveolus development+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051146///striated muscle cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060056///mammary gland involution+++GO:0060416///response to growth hormone+++GO:0071320///cellular response to cAMP+++GO:0071407///cellular response to organic cyclic compound+++GO:1901862///negative regulation of muscle tissue development+++GO:1904205///negative regulation of skeletal muscle hypertrophy+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration 16012 16012 'Igfbp6' mRNA 1791 1625 1540 84.19 75.41 76.81 115.88 117.17 113.73 78.80333333 115.5933333 2830 2791 2686 1652 2769 2.49E-25 0.734586044 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042568///insulin-like growth factor binary complex+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005520///insulin-like growth factor binding+++GO:0019838///growth factor binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding+++GO:0042802///identical protein binding GO:0000187///activation of MAPK activity+++GO:0016477///cell migration+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway 16068 16068 'Il18bp' mRNA 322.37 328.45 341.67 11.33 12.08 13.52 33.43 31.63 30.24 12.31 31.76666667 966.19 883.62 826.65 330.83 892.1533333 3.97E-36 1.418627444 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0042007///interleukin-18 binding GO:0042088///T-helper 1 type immune response 16069 16069 'Jchain' mRNA 85 92 84 2.29 2.44 2.4 9.09 10.42 10.31 2.376666667 9.94 388 434 426 87 416 6.43E-40 2.247773212 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0071748///monomeric IgA immunoglobulin complex+++GO:0071750///dimeric IgA immunoglobulin complex+++GO:0071751///secretory IgA immunoglobulin complex+++GO:0071752///secretory dimeric IgA immunoglobulin complex+++GO:0071756///pentameric IgM immunoglobulin complex "GO:0003697///single-stranded DNA binding+++GO:0003823///antigen binding+++GO:0019862///IgA binding+++GO:0030674///protein binding, bridging+++GO:0031210///phosphatidylcholine binding+++GO:0034987///immunoglobulin receptor binding+++GO:0042803///protein homodimerization activity+++GO:0042834///peptidoglycan binding" GO:0002250///adaptive immune response+++GO:0003094///glomerular filtration+++GO:0006959///humoral immune response+++GO:0019731///antibacterial humoral response+++GO:0045087///innate immune response+++GO:0060267///positive regulation of respiratory burst+++GO:0065003///protein-containing complex assembly 16136 16136 'Igll1' mRNA 39 34 42 2.98 2.57 3.4 0.4 0.27 0.41 2.983333333 0.36 6 4 6 38.33333333 5.333333333 2.18E-06 -2.863104998 05340///Primary immunodeficiency "GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0009897///external side of plasma membrane+++GO:0042571///immunoglobulin complex, circulating" GO:0003823///antigen binding+++GO:0005515///protein binding+++GO:0034987///immunoglobulin receptor binding "GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0006958///complement activation, classical pathway+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0050871///positive regulation of B cell activation" 16145 16145 'Igtp' mRNA 1252.17 1214.08 1230.16 35.2 33.62 36.68 49.65 50.15 47.61 35.16666667 49.13666667 2030.86 2002.38 1884.93 1232.136667 1972.723333 6.95E-18 0.666050728 05145///Toxoplasmosis GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0050700///CARD domain binding+++GO:0051434///BH3 domain binding GO:0000045///autophagosome assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006952///defense response+++GO:0010508///positive regulation of autophagy+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0031648///protein destabilization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035458///cellular response to interferon-beta+++GO:0042742///defense response to bacterium+++GO:0043254///regulation of protein complex assembly+++GO:0045087///innate immune response+++GO:0050821///protein stabilization+++GO:0050829///defense response to Gram-negative bacterium+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0061635///regulation of protein complex stability+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:0098586///cellular response to virus+++GO:1901098///positive regulation of autophagosome maturation 16147 16147 'Ihh' mRNA 5 1 3 0.11 0.02 0.07 0.1 0.02 0.14 0.066666667 0.086666667 5 1 7 3 4.333333333 0.778633045 0.509330116 04340///Hedgehog signaling pathway+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix GO:0005113///patched binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001763///morphogenesis of a branching structure+++GO:0001944///vasculature development+++GO:0001947///heart looping+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003382///epithelial cell morphogenesis+++GO:0003406///retinal pigment epithelium development+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0006029///proteoglycan metabolic process+++GO:0006508///proteolysis+++GO:0007224///smoothened signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0008284///positive regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009790///embryo development+++GO:0009880///embryonic pattern specification+++GO:0010468///regulation of gene expression+++GO:0016539///intein-mediated protein splicing+++GO:0016540///protein autoprocessing+++GO:0030154///cell differentiation+++GO:0030704///vitelline membrane formation+++GO:0031016///pancreas development+++GO:0032355///response to estradiol+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0035264///multicellular organism growth+++GO:0035988///chondrocyte proliferation+++GO:0040008///regulation of growth+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0045453///bone resorption+++GO:0045596///negative regulation of cell differentiation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046639///negative regulation of alpha-beta T cell differentiation+++GO:0048074///negative regulation of eye pigmentation+++GO:0048469///cell maturation+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048666///neuron development+++GO:0048745///smooth muscle tissue development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0060135///maternal process involved in female pregnancy+++GO:0060220///camera-type eye photoreceptor cell fate commitment+++GO:0060323///head morphogenesis+++GO:0061053///somite development+++GO:0072498///embryonic skeletal joint development+++GO:0090136///epithelial cell-cell adhesion+++GO:0097421///liver regeneration 16149 16149 'Cd74' mRNA 5590 5643 4278 269.8 268.35 219.28 454.8 482.48 456.52 252.4766667 464.6 10792 11169 10499 5170.333333 10820 2.15E-48 1.059787452 04612///Antigen processing and presentation+++05152///Tuberculosis+++05168///Herpes simplex virus 1 infection GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005773///vacuole+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0035692///macrophage migration inhibitory factor receptor complex+++GO:0035693///NOS2-CD74 complex+++GO:0042613///MHC class II protein complex "GO:0001540///amyloid-beta binding+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0023026///MHC class II protein complex binding+++GO:0035718///macrophage migration inhibitory factor binding+++GO:0042289///MHC class II protein binding+++GO:0042609///CD4 receptor binding+++GO:0042658///MHC class II protein binding, via antigen binding groove+++GO:0044183///protein binding involved in protein folding+++GO:0050998///nitric-oxide synthase binding" "GO:0000187///activation of MAPK activity+++GO:0001516///prostaglandin biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0002792///negative regulation of peptide secretion+++GO:0002821///positive regulation of adaptive immune response+++GO:0002830///positive regulation of type 2 immune response+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0006457///protein folding+++GO:0006886///intracellular protein transport+++GO:0006952///defense response+++GO:0006955///immune response+++GO:0008283///cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016064///immunoglobulin mediated immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030336///negative regulation of cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033674///positive regulation of kinase activity+++GO:0034341///response to interferon-gamma+++GO:0035691///macrophage migration inhibitory factor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045059///positive thymic T cell selection+++GO:0045060///negative thymic T cell selection+++GO:0045089///positive regulation of innate immune response+++GO:0045581///negative regulation of T cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046597///negative regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0065003///protein-containing complex assembly+++GO:0070206///protein trimerization+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000448///positive regulation of macrophage migration inhibitory factor signaling pathway" 16150 16150 'Ikbkb' mRNA 1346 1465 1427 21.11 22.18 23.29 17.17 17.61 16.37 22.19333333 17.05 1327 1333 1214 1412.666667 1291.333333 0.139830328 -0.142227851 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008385///IkappaB kinase complex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0035631///CD40 receptor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008384///IkappaB kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding+++GO:1990459///transferrin receptor binding GO:0001782///B cell homeostasis+++GO:0006468///protein phosphorylation+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007252///I-kappaB phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0010765///positive regulation of sodium ion transport+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0042325///regulation of phosphorylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0061847///response to cholecystokinin+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072659///protein localization to plasma membrane+++GO:1901216///positive regulation of neuron death+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1903347///negative regulation of bicellular tight junction assembly+++GO:2001259///positive regulation of cation channel activity 16151 16151 'Ikbkg' mRNA 670.52 700 759.37 5.07 5.21 6.11 6.28 6 6.09 5.463333333 6.123333333 952.31 891 897.06 709.9633333 913.4566667 0.00132784 0.348864726 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008385///IkappaB kinase complex+++GO:0032991///protein-containing complex+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:1990450///linear polyubiquitin binding+++GO:1990459///transferrin receptor binding GO:0001782///B cell homeostasis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0010628///positive regulation of gene expression+++GO:0016239///positive regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043276///anoikis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051650///establishment of vesicle localization+++GO:0065003///protein-containing complex assembly+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 16153 16153 'Il10' mRNA 1 3 1 0.05 0.14 0.05 0.2 1.07 0.5 0.08 0.59 5 26 12 1.666666667 14.33333333 0.006606474 3.114329178 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04068///FoxO signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04660///T cell receptor signaling pathway+++04672///Intestinal immune network for IgA production+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05330///Allograft rejection GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005141///interleukin-10 receptor binding+++GO:0046983///protein dimerization activity "GO:0001818///negative regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002237///response to molecule of bacterial origin+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002719///negative regulation of cytokine production involved in immune response+++GO:0002875///negative regulation of chronic inflammatory response to antigenic stimulus+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0008285///negative regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010507///negative regulation of autophagy+++GO:0014823///response to activity+++GO:0014854///response to inactivity+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0030889///negative regulation of B cell proliferation+++GO:0032496///response to lipopolysaccharide+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0034465///response to carbon monoxide+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042493///response to drug+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0043032///positive regulation of macrophage activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045787///positive regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0050728///negative regulation of inflammatory response+++GO:0050807///regulation of synapse organization+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051384///response to glucocorticoid+++GO:0051930///regulation of sensory perception of pain+++GO:0060302///negative regulation of cytokine activity+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071392///cellular response to estradiol stimulus+++GO:0097421///liver regeneration+++GO:1900100///positive regulation of plasma cell differentiation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903034///regulation of response to wounding+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904057///negative regulation of sensory perception of pain+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000352///negative regulation of endothelial cell apoptotic process" 16154 16154 'Il10ra' mRNA 96 103 114 1.49 1.58 1.88 12.75 12.38 12.14 1.65 12.42333333 944 895 870 104.3333333 903 3.40E-115 3.099902109 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04630///JAK-STAT signaling pathway+++05145///Toxoplasmosis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0004920///interleukin-10 receptor activity+++GO:0019969///interleukin-10 binding GO:0010507///negative regulation of autophagy+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0050807///regulation of synapse organization+++GO:0070086///ubiquitin-dependent endocytosis 16155 16155 'Il10rb' mRNA 1429 1458 1447 44.02 44.06 47.33 82.22 89.08 86.94 45.13666667 86.08 3054 3233 3132 1444.666667 3139.666667 8.85E-54 1.108098897 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04630///JAK-STAT signaling pathway+++05145///Toxoplasmosis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0004920///interleukin-10 receptor activity+++GO:0005515///protein binding GO:0019221///cytokine-mediated signaling pathway+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0051607///defense response to virus+++GO:1901857///positive regulation of cellular respiration 16156 16156 'Il11' mRNA 17 12 13 0.5 0.45 0.43 0.62 0.58 0.4 0.46 0.533333333 23 21 15 14 19.66666667 0.511757986 0.477880858 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0005142///interleukin-11 receptor binding+++GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046888///negative regulation of hormone secretion+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation 16157 16157 'Il11ra1' mRNA 3166.44 3288.98 3095.56 103.86 106.21 107.59 96.12 97.27 99.61 105.8866667 97.66666667 3372.13 3328.3 3380.54 3183.66 3360.323333 0.353463779 0.066641186 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004921///interleukin-11 receptor activity+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding GO:0001779///natural killer cell differentiation+++GO:0001890///placenta development+++GO:0007566///embryo implantation+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032502///developmental process+++GO:0038154///interleukin-11-mediated signaling pathway+++GO:0046697///decidualization+++GO:0060135///maternal process involved in female pregnancy+++GO:0060322///head development 16158 16158 'Il11ra2' mRNA 136.15 126.18 137.45 4.27 3.97 4.5 4.59 5.15 3.72 4.246666667 4.486666667 164.66 184.74 124.92 133.26 158.1066667 0.387533953 0.22939018 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004921///interleukin-11 receptor activity+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway 16159 16159 'Il12a' mRNA 28 17 16 1.46 0.87 0.88 2.67 1.81 1.69 1.07 2.056666667 59 40 36 20.33333333 45 0.017926895 1.134426216 04060///Cytokine-cytokine receptor interaction+++04620///Toll-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05321///Inflammatory bowel disease+++05330///Allograft rejection+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005796///Golgi lumen+++GO:0009986///cell surface+++GO:0031904///endosome lumen+++GO:0043514///interleukin-12 complex GO:0005125///cytokine activity+++GO:0005143///interleukin-12 receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042163///interleukin-12 beta subunit binding+++GO:0045513///interleukin-27 binding+++GO:0046982///protein heterodimerization activity GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0006955///immune response+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0009615///response to virus+++GO:0010224///response to UV-B+++GO:0016477///cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0032946///positive regulation of mononuclear cell proliferation+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0035711///T-helper 1 cell activation+++GO:0035744///T-helper 1 cell cytokine production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042832///defense response to protozoan+++GO:0045582///positive regulation of T cell differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050709///negative regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051135///positive regulation of NK T cell activation+++GO:0051726///regulation of cell cycle+++GO:0071222///cellular response to lipopolysaccharide+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0098586///cellular response to virus+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:2000510///positive regulation of dendritic cell chemotaxis 16160 16160 'Il12b' mRNA 0 1 2 0 0.02 0.05 0.27 0.08 0.08 0.023333333 0.143333333 14 4 4 1 7.333333333 0.068843629 2.833181271 04060///Cytokine-cytokine receptor interaction+++04620///Toll-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05321///Inflammatory bowel disease+++05330///Allograft rejection+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005796///Golgi lumen+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031904///endosome lumen+++GO:0043235///receptor complex+++GO:0043514///interleukin-12 complex+++GO:0070743///interleukin-23 complex GO:0004896///cytokine receptor activity+++GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019955///cytokine binding+++GO:0042164///interleukin-12 alpha subunit binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045519///interleukin-23 receptor binding+++GO:0046982///protein heterodimerization activity GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002323///natural killer cell activation involved in immune response+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0007050///cell cycle arrest+++GO:0007166///cell surface receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0010033///response to organic substance+++GO:0010224///response to UV-B+++GO:0010536///positive regulation of activation of Janus kinase activity+++GO:0016477///cell migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019233///sensory perception of pain+++GO:0030101///natural killer cell activation+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0032946///positive regulation of mononuclear cell proliferation+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0035744///T-helper 1 cell cytokine production+++GO:0042093///T-helper cell differentiation+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042832///defense response to protozoan+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050709///negative regulation of protein secretion+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051135///positive regulation of NK T cell activation+++GO:0051142///positive regulation of NK T cell proliferation+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 16161 16161 'Il12rb1' mRNA 63.74 71.9 56.68 0.71 0.8 0.68 0.92 0.75 1 0.73 0.89 86.5 72.82 101.31 64.10666667 86.87666667 0.174303637 0.437768405 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042022///interleukin-12 receptor complex+++GO:0043235///receptor complex+++GO:0072536///interleukin-23 receptor complex GO:0004896///cytokine receptor activity+++GO:0005143///interleukin-12 receptor binding+++GO:0016517///interleukin-12 receptor activity+++GO:0019955///cytokine binding+++GO:0042019///interleukin-23 binding+++GO:0042020///interleukin-23 receptor activity GO:0002230///positive regulation of defense response to virus by host+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032729///positive regulation of interferon-gamma production+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0038155///interleukin-23-mediated signaling pathway+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0071346///cellular response to interferon-gamma 16162 16162 'Il12rb2' mRNA 113.78 128.47 127.06 0.73 0.81 0.86 0.81 0.67 0.66 0.8 0.713333333 134.95 108.59 114.79 123.1033333 119.4433333 0.854259716 -0.062604924 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019955///cytokine binding GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032609///interferon-gamma production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0034097///response to cytokine 16163 16163 'Il13' mRNA 1 2 0 0.05 0.1 0 0.04 0 0 0.05 0.013333333 1 0 0 1 0.333333333 0.736910561 -1.456094215 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04664///Fc epsilon RI signaling pathway+++05200///Pathways in cancer+++05310///Asthma+++05321///Inflammatory bowel disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005144///interleukin-13 receptor binding+++GO:0005515///protein binding GO:0001774///microglial cell activation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010155///regulation of proton transport+++GO:0010628///positive regulation of gene expression+++GO:0030890///positive regulation of B cell proliferation+++GO:0032723///positive regulation of connective tissue growth factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0033861///negative regulation of NAD(P)H oxidase activity+++GO:0035094///response to nicotine+++GO:0042116///macrophage activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043032///positive regulation of macrophage activation+++GO:0043270///positive regulation of ion transport+++GO:0043306///positive regulation of mast cell degranulation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0071345///cellular response to cytokine stimulus+++GO:0071635///negative regulation of transforming growth factor beta production+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901215///negative regulation of neuron death+++GO:1903660///negative regulation of complement-dependent cytotoxicity+++GO:2000231///positive regulation of pancreatic stellate cell proliferation+++GO:2000352///negative regulation of endothelial cell apoptotic process 16164 16164 'Il13ra1' mRNA 348 362 407 5.07 5.19 6.29 15.56 16.42 17.36 5.516666667 16.44666667 1228 1266 1327 372.3333333 1273.666667 1.88E-58 1.760070176 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++05200///Pathways in cancer GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004923///leukemia inhibitory factor receptor activity+++GO:0004924///oncostatin-M receptor activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0016515///interleukin-13 receptor activity+++GO:0019955///cytokine binding GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035772///interleukin-13-mediated signaling pathway+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0048861///leukemia inhibitory factor signaling pathway 16168 16168 'Il15' mRNA 195 194 188 8.39 8.6 8.79 7.94 7.37 6.88 8.593333333 7.396666667 201 183 169 192.3333333 184.3333333 0.764034651 -0.073819159 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04668///TNF signaling pathway+++04672///Intestinal immune network for IgA production+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016607///nuclear speck GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding GO:0001819///positive regulation of cytokine production+++GO:0001866///NK T cell proliferation+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0014732///skeletal muscle atrophy+++GO:0030212///hyaluronan metabolic process+++GO:0030225///macrophage differentiation+++GO:0031667///response to nutrient levels+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042119///neutrophil activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045062///extrathymic T cell selection+++GO:0045580///regulation of T cell differentiation+++GO:0048469///cell maturation+++GO:0048535///lymph node development+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050691///regulation of defense response to virus by host+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050766///positive regulation of phagocytosis+++GO:0050778///positive regulation of immune response+++GO:0071305///cellular response to vitamin D+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1904100///positive regulation of protein O-linked glycosylation 16169 16169 'Il15ra' mRNA 421.04 415 425 11.64 11.83 12.78 13.89 12.42 13.33 12.08333333 13.21333333 546 460.19 513.83 420.3466667 506.6733333 0.056821814 0.254574678 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04672///Intestinal immune network for IgA production+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane GO:0019901///protein kinase binding+++GO:0042010///interleukin-15 receptor activity GO:0007259///JAK-STAT cascade+++GO:0010977///negative regulation of neuron projection development+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0050766///positive regulation of phagocytosis 16170 16170 'Il16' mRNA 637 666 674 6.95 7.56 8.7 10.3 9.87 9.21 7.736666667 9.793333333 854 801 751 659 802 0.01437488 0.269672949 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016607///nuclear speck+++GO:0062023///collagen-containing extracellular matrix+++GO:0090543///Flemming body GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0042609///CD4 receptor binding GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030595///leukocyte chemotaxis+++GO:0032722///positive regulation of chemokine production+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0050729///positive regulation of inflammatory response+++GO:0050930///induction of positive chemotaxis+++GO:0051924///regulation of calcium ion transport+++GO:1902565///positive regulation of neutrophil activation 16172 16172 'Il17ra' mRNA 379 441 382 5.15 5.9 5.51 12.94 11.84 12.18 5.52 12.32 1095 979 999 400.6666667 1024.333333 9.04E-39 1.342816864 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway+++04936///Alcoholic liver disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030368///interleukin-17 receptor activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0009615///response to virus+++GO:0030163///protein catabolic process+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032747///positive regulation of interleukin-23 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045087///innate immune response+++GO:0050729///positive regulation of inflammatory response+++GO:0050832///defense response to fungus+++GO:0071345///cellular response to cytokine stimulus+++GO:0071621///granulocyte chemotaxis+++GO:0072537///fibroblast activation+++GO:0072538///T-helper 17 type immune response+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:2000340///positive regulation of chemokine (C-X-C motif) ligand 1 production 16173 16173 'Il18' mRNA 233 292 229 11.24 13.9 12.2 16.42 18.17 18.28 12.44666667 17.62333333 365 398 406 251.3333333 389.6666667 4.35E-05 0.624652647 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05135///Yersinia infection+++05143///African trypanosomiasis+++05144///Malaria+++05152///Tuberculosis+++05164///Influenza A+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane GO:0005125///cytokine activity+++GO:0045515///interleukin-18 receptor binding GO:0000165///MAPK cascade+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030101///natural killer cell activation+++GO:0030155///regulation of cell adhesion+++GO:0030431///sleep+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032148///activation of protein kinase B activity+++GO:0032635///interleukin-6 production+++GO:0032722///positive regulation of chemokine production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0032930///positive regulation of superoxide anion generation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033030///negative regulation of neutrophil apoptotic process+++GO:0035655///interleukin-18-mediated signaling pathway+++GO:0035744///T-helper 1 cell cytokine production+++GO:0042088///T-helper 1 type immune response+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042119///neutrophil activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042632///cholesterol homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043117///positive regulation of vascular permeability+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051142///positive regulation of NK T cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070328///triglyceride homeostasis+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000256///positive regulation of male germ cell proliferation+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000504///positive regulation of blood vessel remodeling+++GO:2000556///positive regulation of T-helper 1 cell cytokine production 16174 16174 'Il18rap' mRNA 6 2 5 0.16 0.04 0.13 0.72 0.58 0.53 0.11 0.61 68 58 52 4.333333333 59.33333333 6.40E-11 3.759388422 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++05321///Inflammatory bowel disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045092///interleukin-18 receptor complex "GO:0003953///NAD+ nucleosidase activity+++GO:0004908///interleukin-1 receptor activity+++GO:0016787///hydrolase activity+++GO:0042008///interleukin-18 receptor activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0032609///interferon-gamma production+++GO:0032635///interleukin-6 production+++GO:0035655///interleukin-18-mediated signaling pathway+++GO:0035744///T-helper 1 cell cytokine production+++GO:0042119///neutrophil activation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071345///cellular response to cytokine stimulus+++GO:0071351///cellular response to interleukin-18 16175 16175 'Il1a' mRNA 29 43 27 0.84 1.22 0.83 2.69 2.78 2.7 0.963333333 2.723333333 107 108 104 33 106.3333333 6.22E-08 1.681560504 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04217///Necroptosis+++04218///Cellular senescence+++04380///Osteoclast differentiation+++04640///Hematopoietic cell lineage+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04940///Type I diabetes mellitus+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05133///Pertussis+++05140///Leishmaniasis+++05152///Tuberculosis+++05162///Measles+++05164///Influenza A+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05332///Graft-versus-host disease+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface GO:0005125///cytokine activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005507///copper ion binding GO:0001660///fever generation+++GO:0001819///positive regulation of cytokine production+++GO:0002248///connective tissue replacement involved in inflammatory response wound healing+++GO:0006883///cellular sodium ion homeostasis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010893///positive regulation of steroid biosynthetic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031424///keratinization+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033092///positive regulation of immature T cell proliferation in thymus+++GO:0034605///cellular response to heat+++GO:0035234///ectopic germ cell programmed cell death+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045766///positive regulation of angiogenesis+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046688///response to copper ion+++GO:0050714///positive regulation of protein secretion+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0051781///positive regulation of cell division+++GO:0051930///regulation of sensory perception of pain+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1902624///positive regulation of neutrophil migration+++GO:1904445///negative regulation of establishment of Sertoli cell barrier+++GO:2000391///positive regulation of neutrophil extravasation 16176 16176 'Il1b' mRNA 132 117 141 5.57 5.02 6.56 15.3 14.78 15.75 5.716666667 15.27666667 418 382 404 130 401.3333333 3.31E-23 1.611210505 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04640///Hematopoietic cell lineage+++04657///IL-17 signaling pathway+++04659///Th17 cell differentiation+++04668///TNF signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05146///Amoebiasis+++05152///Tuberculosis+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05332///Graft-versus-host disease+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle GO:0005125///cytokine activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005178///integrin binding+++GO:0019904///protein domain specific binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001660///fever generation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009743///response to carbohydrate+++GO:0010573///vascular endothelial growth factor production+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010829///negative regulation of glucose transmembrane transport+++GO:0010942///positive regulation of cell death+++GO:0014050///negative regulation of glutamate secretion+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030213///hyaluronan biosynthetic process+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0030730///sequestering of triglyceride+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0031622///positive regulation of fever generation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032611///interleukin-1 beta production+++GO:0032635///interleukin-6 production+++GO:0032722///positive regulation of chemokine production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0033092///positive regulation of immature T cell proliferation in thymus+++GO:0033198///response to ATP+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0035176///social behavior+++GO:0035234///ectopic germ cell programmed cell death+++GO:0035505///positive regulation of myosin light chain kinase activity+++GO:0035690///cellular response to drug+++GO:0042102///positive regulation of T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043491///protein kinase B signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045833///negative regulation of lipid metabolic process+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045917///positive regulation of complement activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048143///astrocyte activation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0050691///regulation of defense response to virus by host+++GO:0050729///positive regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050767///regulation of neurogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0050796///regulation of insulin secretion+++GO:0050805///negative regulation of synaptic transmission+++GO:0050900///leukocyte migration+++GO:0050995///negative regulation of lipid catabolic process+++GO:0050996///positive regulation of lipid catabolic process+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051781///positive regulation of cell division+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060559///positive regulation of calcidiol 1-monooxygenase activity+++GO:0070164///negative regulation of adiponectin secretion+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070487///monocyte aggregation+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071310///cellular response to organic substance+++GO:0071407///cellular response to organic cyclic compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902680///positive regulation of RNA biosynthetic process+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1903597///negative regulation of gap junction assembly+++GO:2000173///negative regulation of branching morphogenesis of a nerve+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2000556///positive regulation of T-helper 1 cell cytokine production+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 16177 16177 'Il1r1' mRNA 85 87 58 0.92 0.95 0.68 1.16 0.77 0.74 0.85 0.89 121 80 74 76.66666667 91.66666667 0.490676262 0.249061336 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04640///Hematopoietic cell lineage+++04659///Th17 cell differentiation+++04750///Inflammatory mediator regulation of TRP channels+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex "GO:0002020///protease binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004908///interleukin-1 receptor activity+++GO:0004909///interleukin-1, type I, activating receptor activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019966///interleukin-1 binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0009314///response to radiation+++GO:0010286///heat acclimation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032729///positive regulation of interferon-gamma production+++GO:0050727///regulation of inflammatory response+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000556///positive regulation of T-helper 1 cell cytokine production+++GO:2000661///positive regulation of interleukin-1-mediated signaling pathway+++GO:2001224///positive regulation of neuron migration 16178 16178 'Il1r2' mRNA 17 23 22 0.69 0.98 0.98 3.25 2.81 1.84 0.883333333 2.633333333 89 77 49 20.66666667 71.66666667 1.09E-05 1.778755697 04060///Cytokine-cytokine receptor interaction+++04640///Hematopoietic cell lineage+++05146///Amoebiasis+++05166///Human T-cell leukemia virus 1 infection+++05202///Transcriptional misregulation in cancer+++05215///Prostate cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004908///interleukin-1 receptor activity+++GO:0004910///interleukin-1, type II, blocking receptor activity+++GO:0019966///interleukin-1 binding" GO:0010955///negative regulation of protein processing+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032690///negative regulation of interleukin-1 alpha production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway 16179 16179 'Irak1' mRNA 616.64 594.08 582.63 8.7 8.25 8.7 11.4 10.77 10.72 8.55 10.96333333 934.06 862.23 848.83 597.7833333 881.7066667 2.86E-08 0.54885082 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04722///Neurotrophin signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity "GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007254///JNK cascade+++GO:0007568///aging+++GO:0016310///phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032481///positive regulation of type I interferon production+++GO:0032494///response to peptidoglycan+++GO:0032496///response to lipopolysaccharide+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034605///cellular response to heat+++GO:0035556///intracellular signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060337///type I interferon signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071456///cellular response to hypoxia+++GO:0090370///negative regulation of cholesterol efflux+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell" 16180 16180 'Il1rap' mRNA 300 308 290 3.98 3.82 3.89 6.43 6.78 5.6 3.896666667 6.27 537 533 454 299.3333333 508 1.42E-08 0.751545007 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04659///Th17 cell differentiation+++04750///Inflammatory mediator regulation of TRP channels GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0098978///glutamatergic synapse "GO:0002114///interleukin-33 receptor activity+++GO:0003953///NAD+ nucleosidase activity+++GO:0004908///interleukin-1 receptor activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating+++GO:1990782///protein tyrosine kinase binding" GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032623///interleukin-2 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0038172///interleukin-33-mediated signaling pathway+++GO:0045087///innate immune response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051965///positive regulation of synapse assembly+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099545///trans-synaptic signaling by trans-synaptic complex+++GO:0099560///synaptic membrane adhesion+++GO:1900006///positive regulation of dendrite development+++GO:1905606///regulation of presynapse assembly 16181 16181 'Il1rn' mRNA 159 158 157 3.57 3.53 3.78 55.93 55.25 56.44 3.626666667 55.87333333 2854 2752 2789 158 2798.333333 0 4.13510907 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031982///vesicle "GO:0005125///cytokine activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005150///interleukin-1, type I receptor binding+++GO:0005151///interleukin-1, type II receptor binding+++GO:0005152///interleukin-1 receptor antagonist activity+++GO:0045352///interleukin-1 type I receptor antagonist activity+++GO:0045353///interleukin-1 type II receptor antagonist activity" GO:0001660///fever generation+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0006629///lipid metabolic process+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007613///memory+++GO:0014050///negative regulation of glutamate secretion+++GO:0019233///sensory perception of pain+++GO:0030073///insulin secretion+++GO:0030336///negative regulation of cell migration+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0043066///negative regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045837///negative regulation of membrane potential+++GO:0051384///response to glucocorticoid+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway 16182 16182 'Il18r1' mRNA 18 27 26 0.49 0.79 0.62 1.78 1.45 1.67 0.633333333 1.633333333 79 70 74 23.66666667 74.33333333 9.10E-06 1.63678065 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04668///TNF signaling pathway+++05321///Inflammatory bowel disease GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045092///interleukin-18 receptor complex "GO:0003953///NAD+ nucleosidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042007///interleukin-18 binding+++GO:0042008///interleukin-18 receptor activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0030101///natural killer cell activation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0035655///interleukin-18-mediated signaling pathway+++GO:0045063///T-helper 1 cell differentiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000556///positive regulation of T-helper 1 cell cytokine production 16184 16184 'Il2ra' mRNA 20 22.15 12 0.24 0.26 0.15 0.56 0.61 0.87 0.216666667 0.68 53 57 80 18.05 63.33333333 2.03E-05 1.812826176 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004911///interleukin-2 receptor activity+++GO:0005515///protein binding+++GO:0019976///interleukin-2 binding GO:0002376///immune system process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0002664///regulation of T cell tolerance induction+++GO:0006924///activation-induced cell death of T cells+++GO:0006954///inflammatory response+++GO:0007219///Notch signaling pathway+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043029///T cell homeostasis+++GO:0045582///positive regulation of T cell differentiation+++GO:0046013///regulation of T cell homeostatic proliferation+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:0050728///negative regulation of inflammatory response 16185 16185 'Il2rb' mRNA 44 40 36 0.75 0.61 0.7 1.07 1.29 1.24 0.686666667 1.2 70 80 79 40 76.33333333 0.005500571 0.923936365 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0004911///interleukin-2 receptor activity+++GO:0019976///interleukin-2 binding+++GO:0042010///interleukin-15 receptor activity GO:0019221///cytokine-mediated signaling pathway+++GO:0030101///natural killer cell activation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0050766///positive regulation of phagocytosis 16186 16186 'Il2rg' mRNA 77 75 64 2.7 2.76 2.55 42.81 45.28 41.55 2.67 43.21333333 1382 1412 1297 72 1363.666667 1.91E-212 4.233596647 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05321///Inflammatory bowel disease+++05340///Primary immunodeficiency GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding+++GO:0019976///interleukin-2 binding+++GO:0042010///interleukin-15 receptor activity "GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032831///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0045579///positive regulation of B cell differentiation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0050766///positive regulation of phagocytosis" 16188 16188 'Il3ra' mRNA 83 84 65 3.41 3.14 2.63 13.23 9.29 11.91 3.06 11.47666667 372 252 331 77.33333333 318.3333333 1.83E-23 2.030331821 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004912///interleukin-3 receptor activity+++GO:0019955///cytokine binding+++GO:0019978///interleukin-3 binding GO:0001558///regulation of cell growth+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030224///monocyte differentiation+++GO:0038156///interleukin-3-mediated signaling pathway 16189 16189 'Il4' mRNA 0 0 2 0 0 0.28 0 0.12 0.24 0.093333333 0.12 0 1 2 0.666666667 1 0.886537466 0.525102185 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04672///Intestinal immune network for IgA production+++05140///Leishmaniasis+++05200///Pathways in cancer+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05330///Allograft rejection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005136///interleukin-4 receptor binding+++GO:0008083///growth factor activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001774///microglial cell activation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002227///innate immune response in mucosa+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002674///negative regulation of acute inflammatory response+++GO:0002677///negative regulation of chronic inflammatory response+++GO:0006914///autophagy+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008203///cholesterol metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010155///regulation of proton transport+++GO:0010628///positive regulation of gene expression+++GO:0010633///negative regulation of epithelial cell migration+++GO:0016239///positive regulation of macroautophagy+++GO:0030335///positive regulation of cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031296///B cell costimulation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042110///T cell activation+++GO:0042113///B cell activation+++GO:0042116///macrophage activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042832///defense response to protozoan+++GO:0042976///activation of Janus kinase activity+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043031///negative regulation of macrophage activation+++GO:0043306///positive regulation of mast cell degranulation+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045064///T-helper 2 cell differentiation+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045582///positive regulation of T cell differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048295///positive regulation of isotype switching to IgE isotypes+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050776///regulation of immune response+++GO:0050868///negative regulation of T cell activation+++GO:0050871///positive regulation of B cell activation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070351///negative regulation of white fat cell proliferation+++GO:0071677///positive regulation of mononuclear cell migration+++GO:0097028///dendritic cell differentiation+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0150076///neuroinflammatory response+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1901741///positive regulation of myoblast fusion+++GO:1901857///positive regulation of cellular respiration+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903660///negative regulation of complement-dependent cytotoxicity+++GO:1903845///negative regulation of cellular response to transforming growth factor beta stimulus+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000424///positive regulation of eosinophil chemotaxis+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:2001171///positive regulation of ATP biosynthetic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 16190 16190 'Il4ra' mRNA 965 1070 1046 10.06 10.98 11.59 30.59 30.23 31.49 10.87666667 30.77 3378 3261 3365 1027 3334.666667 3.71E-116 1.686336369 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0005515///protein binding GO:0002376///immune system process+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0002639///positive regulation of immunoglobulin production+++GO:0016064///immunoglobulin mediated immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032722///positive regulation of chemokine production+++GO:0042127///regulation of cell proliferation+++GO:0042832///defense response to protozoan+++GO:0043032///positive regulation of macrophage activation+++GO:0043306///positive regulation of mast cell degranulation+++GO:0045626///negative regulation of T-helper 1 cell differentiation+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901741///positive regulation of myoblast fusion 16191 16191 'Il5' mRNA 2 3 3 0.08 0.11 0.12 0.03 0.07 0.03 0.103333333 0.043333333 1 2 1 2.666666667 1.333333333 0.637315843 -1.011001669 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04672///Intestinal immune network for IgA production+++05200///Pathways in cancer+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05330///Allograft rejection GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005137///interleukin-5 receptor binding+++GO:0008083///growth factor activity "GO:0002639///positive regulation of immunoglobulin production+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030890///positive regulation of B cell proliferation+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0071803///positive regulation of podosome assembly" 16192 16192 'Il5ra' mRNA 196.2 198.92 235.04 2.98 2.99 3.81 0.4 0.2 0.67 3.26 0.423333333 29.99 15 49.09 210.0533333 31.36 1.99E-19 -2.776287603 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding GO:0002437///inflammatory response to antigenic stimulus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032674///regulation of interleukin-5 production+++GO:0071310///cellular response to organic substance 16193 16193 'Il6' mRNA 1 0 0 0.06 0 0 0.28 0.1 0.15 0.02 0.176666667 6 2 3 0.333333333 3.666666667 0.133883855 3.33368781 01521///EGFR tyrosine kinase inhibitor resistance+++01523///Antifolate resistance+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04657///IL-17 signaling pathway+++04659///Th17 cell differentiation+++04668///TNF signaling pathway+++04672///Intestinal immune network for IgA production+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05332///Graft-versus-host disease+++05410///Hypertrophic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005896///interleukin-6 receptor complex+++GO:0009897///external side of plasma membrane GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005138///interleukin-6 receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity "GO:0001781///neutrophil apoptotic process+++GO:0001878///response to yeast+++GO:0002262///myeloid cell homeostasis+++GO:0002314///germinal center B cell differentiation+++GO:0002384///hepatic immune response+++GO:0002526///acute inflammatory response+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002675///positive regulation of acute inflammatory response+++GO:0006469///negative regulation of protein kinase activity+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0010467///gene expression+++GO:0010573///vascular endothelial growth factor production+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010976///positive regulation of neuron projection development+++GO:0010996///response to auditory stimulus+++GO:0014015///positive regulation of gliogenesis+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031000///response to caffeine+++GO:0031018///endocrine pancreas development+++GO:0031175///neuron projection development+++GO:0031294///lymphocyte costimulation+++GO:0031667///response to nutrient levels+++GO:0031669///cellular response to nutrient levels+++GO:0032496///response to lipopolysaccharide+++GO:0032682///negative regulation of chemokine production+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032745///positive regulation of interleukin-21 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034097///response to cytokine+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042060///wound healing+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0042127///regulation of cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042593///glucose homeostasis+++GO:0042832///defense response to protozoan+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043200///response to amino acid+++GO:0043410///positive regulation of MAPK cascade+++GO:0045188///regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045454///cell redox homeostasis+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045727///positive regulation of translation+++GO:0045740///positive regulation of DNA replication+++GO:0045779///negative regulation of bone resorption+++GO:0045837///negative regulation of membrane potential+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046677///response to antibiotic+++GO:0046716///muscle cell cellular homeostasis+++GO:0046849///bone remodeling+++GO:0046888///negative regulation of hormone secretion+++GO:0048635///negative regulation of muscle organ development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050796///regulation of insulin secretion+++GO:0050871///positive regulation of B cell activation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051384///response to glucocorticoid+++GO:0051592///response to calcium ion+++GO:0051602///response to electrical stimulus+++GO:0051607///defense response to virus+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0061470///T follicular helper cell differentiation+++GO:0070091///glucagon secretion+++GO:0070092///regulation of glucagon secretion+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071392///cellular response to estradiol stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0072574///hepatocyte proliferation+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0097421///liver regeneration+++GO:0098586///cellular response to virus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1901731///positive regulation of platelet aggregation+++GO:1902512///positive regulation of apoptotic DNA fragmentation+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1904894///positive regulation of STAT cascade+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1990646///cellular response to prolactin+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:2000635///negative regulation of primary miRNA processing+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway" 16194 16194 'Il6ra' mRNA 326 338 320 5.26 5.37 5.48 13.23 11.48 11.84 5.37 12.18333333 943 799 817 328 853 2.02E-34 1.366006701 01521///EGFR tyrosine kinase inhibitor resistance+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++04659///Th17 cell differentiation+++04932///Non-alcoholic fatty liver disease+++05163///Human cytomegalovirus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005896///interleukin-6 receptor complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032809///neuronal cell body membrane+++GO:0043235///receptor complex+++GO:0070110///ciliary neurotrophic factor receptor complex GO:0004896///cytokine receptor activity+++GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004915///interleukin-6 receptor activity+++GO:0004921///interleukin-11 receptor activity+++GO:0005138///interleukin-6 receptor binding+++GO:0019899///enzyme binding+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding+++GO:0019981///interleukin-6 binding+++GO:0042803///protein homodimerization activity+++GO:0070119///ciliary neurotrophic factor binding GO:0008284///positive regulation of cell proliferation+++GO:0010536///positive regulation of activation of Janus kinase activity+++GO:0010573///vascular endothelial growth factor production+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031018///endocrine pancreas development+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0034097///response to cytokine+++GO:0038154///interleukin-11-mediated signaling pathway+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043410///positive regulation of MAPK cascade+++GO:0048589///developmental growth+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0072540///T-helper 17 cell lineage commitment+++GO:1901731///positive regulation of platelet aggregation 16195 16195 'Il6st' mRNA 3482 3599 3364 34 34.55 34.85 53.88 50.18 49.52 34.46666667 51.19333333 6354 5780 5656 3481.666667 5930 2.17E-38 0.756057658 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++05167///Kaposi sarcoma-associated herpesvirus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005896///interleukin-6 receptor complex+++GO:0005900///oncostatin-M receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0070110///ciliary neurotrophic factor receptor complex GO:0004896///cytokine receptor activity+++GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004915///interleukin-6 receptor activity+++GO:0004921///interleukin-11 receptor activity+++GO:0004923///leukemia inhibitory factor receptor activity+++GO:0004924///oncostatin-M receptor activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005138///interleukin-6 receptor binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding+++GO:0019981///interleukin-6 binding+++GO:0042802///identical protein binding+++GO:0097110///scaffold protein binding GO:0005977///glycogen metabolic process+++GO:0006642///triglyceride mobilization+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0008593///regulation of Notch signaling pathway+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0038154///interleukin-11-mediated signaling pathway+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048861///leukemia inhibitory factor signaling pathway+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0060576///intestinal epithelial cell development+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070104///negative regulation of interleukin-6-mediated signaling pathway+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway 16196 16196 'Il7' mRNA 11 15 14 0.21 0.28 0.27 0.62 0.43 0.52 0.253333333 0.523333333 37 26 31 13.33333333 31.33333333 0.027967997 1.21727143 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005139///interleukin-7 receptor binding+++GO:0008083///growth factor activity GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0002360///T cell lineage commitment+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030890///positive regulation of B cell proliferation+++GO:0032722///positive regulation of chemokine production+++GO:0043086///negative regulation of catalytic activity+++GO:0045453///bone resorption+++GO:0045579///positive regulation of B cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0046622///positive regulation of organ growth+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 16197 16197 'Il7r' mRNA 11 15 11.96 0.19 0.25 0.2 7.96 6.13 5.86 0.213333333 6.65 543 415 391 12.65333333 449.6666667 6.19E-70 5.175382867 04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage+++05200///Pathways in cancer+++05340///Primary immunodeficiency GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity GO:0000902///cell morphogenesis+++GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0002377///immunoglobulin production+++GO:0008284///positive regulation of cell proliferation+++GO:0008361///regulation of cell size+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030217///T cell differentiation+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0042100///B cell proliferation+++GO:0048535///lymph node development+++GO:0048872///homeostasis of number of cells+++GO:0050830///defense response to Gram-positive bacterium+++GO:0070233///negative regulation of T cell apoptotic process+++GO:1904894///positive regulation of STAT cascade 16199 16199 'Il9r' mRNA 4 2 0 0.05 0.02 0 0.01 0 0 0.023333333 0.003333333 1 0 0 2 0.333333333 0.425801777 -2.461127191 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0004919///interleukin-9 receptor activity+++GO:0019983///interleukin-9 binding GO:0016064///immunoglobulin mediated immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0042100///B cell proliferation+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 16201 16201 'Ilf3' mRNA 2321 2509 2538 35.54 37.62 41.34 29.52 29.62 29.42 38.16666667 29.52 2217 2164 2148 2456 2176.333333 0.020458054 -0.188144423 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0019899///enzyme binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding "GO:0006468///protein phosphorylation+++GO:0006479///protein methylation+++GO:0017148///negative regulation of translation+++GO:0045071///negative regulation of viral genome replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051607///defense response to virus" 16202 16202 'Ilk' mRNA 2532.54 2677.98 2533.91 82.26 85.94 87.69 110.73 113.04 110.4 85.29666667 111.39 3901.93 3895.85 3776.92 2581.476667 3858.233333 5.29E-20 0.568197973 03320///PPAR signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05213///Endometrial cancer GO:0001725///stress fiber+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043034///costamere+++GO:0043195///terminal bouton+++GO:0043198///dendritic shaft GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding "GO:0000902///cell morphogenesis+++GO:0001558///regulation of cell growth+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0003151///outflow tract morphogenesis+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007050///cell cycle arrest+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007569///cell aging+++GO:0008284///positive regulation of cell proliferation+++GO:0009967///positive regulation of signal transduction+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010761///fibroblast migration+++GO:0014044///Schwann cell development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0021675///nerve development+++GO:0022011///myelination in peripheral nervous system+++GO:0030030///cell projection organization+++GO:0030335///positive regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032288///myelin assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042327///positive regulation of phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048812///neuron projection morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097435///supramolecular fiber organization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000178///negative regulation of neural precursor cell proliferation" 16205 16205 'Gimap1' mRNA 104.35 107 119.85 4.09 4.14 4.99 6.08 7.15 6.64 4.406666667 6.623333333 178.05 204.22 187.73 110.4 190 2.87E-04 0.772692604 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation 16206 16206 'Lrig1' mRNA 473 502.97 415 4.77 4.9 4.39 5.3 4.93 5.48 4.686666667 5.236666667 608.34 524.59 565.58 463.6566667 566.17 0.024810189 0.277891184 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0007605///sensory perception of sound+++GO:0022405///hair cycle process+++GO:0032474///otolith morphogenesis+++GO:0060384///innervation 16210 16210 'Impact' mRNA 1925 1839 1706 28.61 26.7 27.22 21.89 19.21 21.79 27.51 20.96333333 1710 1433 1615 1823.333333 1586 0.011063166 -0.212954545 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0043022///ribosome binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0031333///negative regulation of protein complex assembly+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0045666///positive regulation of neuron differentiation+++GO:0060548///negative regulation of cell death+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071264///positive regulation of translational initiation in response to starvation+++GO:0071468///cellular response to acidic pH+++GO:0071494///cellular response to UV-C+++GO:0072755///cellular response to benomyl+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:1990138///neuron projection extension+++GO:1990253///cellular response to leucine starvation 16211 16211 'Kpnb1' mRNA 1239 1242 1185 11.13 10.97 11.29 13.97 13.05 13.99 11.13 13.67 1790 1634 1737 1222 1720.333333 2.08E-10 0.481407172 03013///Nucleocytoplasmic transport+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0071782///endoplasmic reticulum tubular network GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0019894///kinesin binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0051879///Hsp90 protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0061676///importin-alpha family protein binding GO:0006606///protein import into nucleus+++GO:0006610///ribosomal protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007080///mitotic metaphase plate congression+++GO:0015031///protein transport+++GO:0030953///astral microtubule organization+++GO:0031291///Ran protein signal transduction+++GO:0040001///establishment of mitotic spindle localization+++GO:0045184///establishment of protein localization+++GO:0090307///mitotic spindle assembly 16319 16319 'Incenp' mRNA 179 219 168 3.12 3.71 3.08 10.44 9.52 10.55 3.303333333 10.17 694 622 680 188.6666667 665.3333333 9.87E-43 1.808759539 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000793///condensed chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0000801///central element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0010369///chromocenter+++GO:0016604///nuclear body+++GO:0030496///midbody+++GO:0032133///chromosome passenger complex+++GO:0032991///protein-containing complex+++GO:1990385///meiotic spindle midzone" GO:0043539///protein serine/threonine kinase activator activity GO:0000070///mitotic sister chromatid segregation+++GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0010032///meiotic chromosome condensation+++GO:0016572///histone phosphorylation+++GO:0051257///meiotic spindle midzone assembly+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1902412///regulation of mitotic cytokinesis 16322 16322 'Inha' mRNA 894 807 676 27.4 23.77 21.99 8.45 6.68 8.6 24.38666667 7.91 294 235 296 792.3333333 275 1.34E-32 -1.535632296 04060///Cytokine-cytokine receptor interaction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0034673///inhibin-betaglycan-ActRII complex+++GO:0043025///neuronal cell body+++GO:0043512///inhibin A complex+++GO:0043513///inhibin B complex GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0008083///growth factor activity+++GO:0034711///inhibin binding+++GO:0044877///protein-containing complex binding GO:0001541///ovarian follicle development+++GO:0008584///male gonad development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0042541///hemoglobin biosynthetic process+++GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0051726///regulation of cell cycle+++GO:0060395///SMAD protein signal transduction 16323 16323 'Inhba' mRNA 519.99 593.13 522 3.9 4.46 3.93 2.81 2.64 2.76 4.096666667 2.736666667 418.78 381.94 395.71 545.04 398.81 1.52E-04 -0.463915605 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043509///activin A complex+++GO:0043512///inhibin A complex+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0008083///growth factor activity+++GO:0017046///peptide hormone binding+++GO:0034711///inhibin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0070699///type II activin receptor binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001541///ovarian follicle development+++GO:0001707///mesoderm formation+++GO:0001942///hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0010628///positive regulation of gene expression+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0021773///striatal medium spiny neuron differentiation+++GO:0030308///negative regulation of cell growth+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032924///activin receptor signaling pathway+++GO:0035987///endodermal cell differentiation+++GO:0042476///odontogenesis+++GO:0042493///response to drug+++GO:0042541///hemoglobin biosynthetic process+++GO:0042701///progesterone secretion+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046880///regulation of follicle-stimulating hormone secretion+++GO:0048333///mesodermal cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0051799///negative regulation of hair follicle development+++GO:0060021///roof of mouth development+++GO:0060279///positive regulation of ovulation+++GO:0060395///SMAD protein signal transduction+++GO:0061029///eyelid development in camera-type eye+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071397///cellular response to cholesterol+++GO:0097154///GABAergic neuron differentiation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand" 16324 16324 'Inhbb' mRNA 4 2 1 0.05 0.02 0.01 0.11 0.12 0.06 0.026666667 0.096666667 10 11 5 2.333333333 8.666666667 0.120248506 1.892129167 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043513///inhibin B complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0008083///growth factor activity+++GO:0034711///inhibin binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0001654///eye development+++GO:0009267///cellular response to starvation+++GO:0009611///response to wounding+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032686///negative regulation of hepatocyte growth factor production+++GO:0032869///cellular response to insulin stimulus+++GO:0032924///activin receptor signaling pathway+++GO:0044320///cellular response to leptin stimulus+++GO:0045444///fat cell differentiation+++GO:0046676///negative regulation of insulin secretion+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0048599///oocyte development+++GO:0060279///positive regulation of ovulation+++GO:0060395///SMAD protein signal transduction+++GO:0071397///cellular response to cholesterol+++GO:2001235///positive regulation of apoptotic signaling pathway 16325 16325 'Inhbc' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction 16328 16328 'Cep250' mRNA 407 409 358 2.74 2.65 2.56 3.27 2.5 2.76 2.65 2.843333333 529 413 416 391.3333333 452.6666667 0.192736446 0.198153792 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031616///spindle pole centrosome+++GO:0032991///protein-containing complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0008104///protein localization+++GO:0010457///centriole-centriole cohesion+++GO:0030030///cell projection organization+++GO:0030997///regulation of centriole-centriole cohesion+++GO:0033365///protein localization to organelle+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060271///cilium assembly+++GO:1904781///positive regulation of protein localization to centrosome+++GO:1905515///non-motile cilium assembly 16329 16329 'Inpp1' mRNA 1100.16 1105 1002.27 18.8 19.14 18.88 10.85 9.75 9.4 18.94 10 631.63 591.04 555.01 1069.143333 592.56 2.58E-20 -0.862730952 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system "GO:0004441///inositol-1,4-bisphosphate 1-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0046854///phosphatidylinositol phosphorylation+++GO:0046855///inositol phosphate dephosphorylation 16330 16330 'Inpp5b' mRNA 811 777 838 11.51 10.86 12.6 10.33 11.22 9.18 11.65666667 10.24333333 837 889 721 808.6666667 815.6666667 0.998591786 -0.001185477 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052745///inositol phosphate phosphatase activity" GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0030317///flagellated sperm motility+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0070613///regulation of protein processing 16331 16331 'Inpp5d' mRNA 125 134 129 1.52 1.44 1.55 14.93 14.59 15.61 1.503333333 15.04333333 1549 1506 1507 129.3333333 1520.666667 1.64E-217 3.544092142 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton+++GO:0045121///membrane raft "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0030487///inositol-4,5-bisphosphate 5-phosphatase activity+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0034594///phosphatidylinositol trisphosphate phosphatase activity+++GO:0051425///PTB domain binding+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity" GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0009968///negative regulation of signal transduction+++GO:0016064///immunoglobulin mediated immune response+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0032715///negative regulation of interleukin-6 production+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0045579///positive regulation of B cell differentiation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045656///negative regulation of monocyte differentiation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045779///negative regulation of bone resorption+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0050777///negative regulation of immune response+++GO:0050869///negative regulation of B cell activation 16332 16332 'Inppl1' mRNA 1805 1837 1313 19.08 19.21 14.9 16.22 15.74 16.99 17.73 16.31666667 1725 1654 1766 1651.666667 1715 0.708985955 0.049156366 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04662///B cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04910///Insulin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0003824///catalytic activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0042169///SH2 domain binding" GO:0001958///endochondral ossification+++GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006897///endocytosis+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0008156///negative regulation of DNA replication+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010629///negative regulation of gene expression+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:0032868///response to insulin+++GO:0032957///inositol trisphosphate metabolic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0044255///cellular lipid metabolic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0097178///ruffle assembly 16336 16336 'Insl3' mRNA 0 1.28 3.32 0 0.17 0.46 0 0.78 0 0.21 0.26 0 6.55 0 1.533333333 2.183333333 0.863090843 0.557912276 04080///Neuroactive ligand-receptor interaction+++04926///Relaxin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0002020///protease binding+++GO:0005179///hormone activity GO:0001556///oocyte maturation+++GO:0001701///in utero embryonic development+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0010634///positive regulation of epithelial cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0090303///positive regulation of wound healing+++GO:2000018///regulation of male gonad development 16337 16337 'Insr' mRNA 3425 3554 3142 19.16 19.55 18.66 15.29 14.37 14.68 19.12333333 14.78 3148 2891 2927 3373.666667 2988.666667 0.003273211 -0.185516249 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04361///Axon regeneration+++04520///Adherens junction+++04910///Insulin signaling pathway+++04913///Ovarian steroidogenesis+++04923///Regulation of lipolysis in adipocytes+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04960///Aldosterone-regulated sodium reabsorption+++05010///Alzheimer disease+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005899///insulin receptor complex+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031981///nuclear lumen+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane+++GO:0060417///yolk GO:0000166///nucleotide binding+++GO:0001540///amyloid-beta binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005009///insulin-activated receptor activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031405///lipoic acid binding+++GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding+++GO:0038024///cargo receptor activity+++GO:0042802///identical protein binding+++GO:0043423///3-phosphoinositide-dependent protein kinase binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043559///insulin binding+++GO:0043560///insulin receptor substrate binding+++GO:0044877///protein-containing complex binding+++GO:0051425///PTB domain binding "GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002092///positive regulation of receptor internalization+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006898///receptor-mediated endocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008544///epidermis development+++GO:0008584///male gonad development+++GO:0009887///animal organ morphogenesis+++GO:0010310///regulation of hydrogen peroxide metabolic process+++GO:0010560///positive regulation of glycoprotein biosynthetic process+++GO:0010629///negative regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019087///transformation of host cell by virus+++GO:0030238///male sex determination+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0031017///exocrine pancreas development+++GO:0031667///response to nutrient levels+++GO:0032147///activation of protein kinase activity+++GO:0032148///activation of protein kinase B activity+++GO:0032410///negative regulation of transporter activity+++GO:0032869///cellular response to insulin stimulus+++GO:0033674///positive regulation of kinase activity+++GO:0034612///response to tumor necrosis factor+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042327///positive regulation of phosphorylation+++GO:0042593///glucose homeostasis+++GO:0043243///positive regulation of protein complex disassembly+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045821///positive regulation of glycolytic process+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045995///regulation of embryonic development+++GO:0046326///positive regulation of glucose import+++GO:0046777///protein autophosphorylation+++GO:0048639///positive regulation of developmental growth+++GO:0051446///positive regulation of meiotic cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060267///positive regulation of respiratory burst+++GO:0071363///cellular response to growth factor stimulus+++GO:0097062///dendritic spine maintenance+++GO:0097242///amyloid-beta clearance+++GO:1990535///neuron projection maintenance+++GO:2000194///regulation of female gonad development+++GO:2000252///negative regulation of feeding behavior" 16341 16341 'Eif3e' mRNA 1328 1416 1407 50.72 53.33 57.01 69.85 68.04 71.1 53.68666667 69.66333333 2101 1997 2069 1383.666667 2055.666667 3.75E-13 0.557967455 05160///Hepatitis C "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0016605///PML body+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071540///eukaryotic translation initiation factor 3 complex, eIF3e" GO:0003743///translation initiation factor activity+++GO:0047485///protein N-terminus binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0045727///positive regulation of translation+++GO:1902416///positive regulation of mRNA binding" 16348 16348 'Invs' mRNA 406.12 449.47 362.77 3.59 4.03 3.37 2.18 1.9 2.14 3.663333333 2.073333333 283.85 242.74 265.38 406.12 263.99 9.04E-06 -0.633050496 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097543///ciliary inversin compartment+++GO:0097546///ciliary base GO:0005515///protein binding+++GO:0005516///calmodulin binding GO:0001822///kidney development+++GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0009791///post-embryonic development+++GO:0016055///Wnt signaling pathway+++GO:0031016///pancreas development+++GO:0048513///animal organ development+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904108///protein localization to ciliary inversin compartment 16351 16351 'Ipp' mRNA 712.38 835.68 687.11 14.92 17.31 15.2 12.6 10.54 10.92 15.81 11.35333333 679.53 550.32 568.99 745.0566667 599.6133333 0.006294656 -0.325217147 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003779///actin binding 16362 16362 'Irf1' mRNA 685 766 728 18.45 20.59 21.07 39.5 36.66 38.67 20.03666667 38.27666667 1682 1555 1605 726.3333333 1614 1.51E-40 1.139295239 04625///C-type lectin receptor signaling pathway+++04668///TNF signaling pathway+++04917///Prolactin signaling pathway+++05133///Pertussis+++05165///Human papillomavirus infection GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0002376///immune system process+++GO:0002819///regulation of adaptive immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0032481///positive regulation of type I interferon production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0034124///regulation of MyD88-dependent toll-like receptor signaling pathway+++GO:0035458///cellular response to interferon-beta+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0043374///CD8-positive, alpha-beta T cell differentiation+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050776///regulation of immune response+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060416///response to growth hormone+++GO:0071260///cellular response to mechanical stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071375///cellular response to peptide hormone stimulus+++GO:2000564///regulation of CD8-positive, alpha-beta T cell proliferation" 16363 16363 'Irf2' mRNA 855 889 619 17.39 17.7 12.93 16.08 16.07 17.72 16.00666667 16.62333333 919 878 968 787.6666667 921.6666667 0.075107458 0.221662326 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus" 16364 16364 'Irf4' mRNA 12 15 1 0.13 0.17 0.01 0.41 0.36 0.21 0.103333333 0.326666667 42 31 21 9.333333333 31.33333333 0.012479193 1.756523799 04659///Th17 cell differentiation GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0042832///defense response to protozoan+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043388///positive regulation of DNA binding+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0120162///positive regulation of cold-induced thermogenesis" 16365 16365 'Acod1' mRNA 122 121 123 2.62 2.56 2.8 10.88 9.9 11.41 2.66 10.73 583 518 592 122 564.3333333 4.35E-51 2.19692496 00660///C5-Branched dibasic acid metabolism GO:0005739///mitochondrion GO:0016829///lyase activity+++GO:0047613///aconitate decarboxylase activity GO:0002376///immune system process+++GO:0002760///positive regulation of antimicrobial humoral response+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0007566///embryo implantation+++GO:0009617///response to bacterium+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032480///negative regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0035458///cellular response to interferon-beta+++GO:0045087///innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0050728///negative regulation of inflammatory response+++GO:0051607///defense response to virus+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071393///cellular response to progesterone stimulus+++GO:0072573///tolerance induction to lipopolysaccharide+++GO:2000379///positive regulation of reactive oxygen species metabolic process 16367 16367 'Irs1' mRNA 606 538 563 3.47 3.03 3.42 2.38 1.82 2.32 3.306666667 2.173333333 479 358 452 569 429.6666667 0.002241259 -0.419786174 "04022///cGMP-PKG signaling pathway+++04068///FoxO signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++05010///Alzheimer disease+++05206///MicroRNAs in cancer+++05415///Diabetic cardiomyopathy" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005899///insulin receptor complex+++GO:0005901///caveola+++GO:0036064///ciliary basal body+++GO:0043231///intracellular membrane-bounded organelle GO:0001784///phosphotyrosine residue binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005080///protein kinase C binding+++GO:0005158///insulin receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0042169///SH2 domain binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010907///positive regulation of glucose metabolic process+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016042///lipid catabolic process+++GO:0030073///insulin secretion+++GO:0030335///positive regulation of cell migration+++GO:0030879///mammary gland development+++GO:0031000///response to caffeine+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0034504///protein localization to nucleus+++GO:0042327///positive regulation of phosphorylation+++GO:0043434///response to peptide hormone+++GO:0043491///protein kinase B signaling+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0046326///positive regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046676///negative regulation of insulin secretion+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0070094///positive regulation of glucagon secretion+++GO:0071398///cellular response to fatty acid+++GO:0090275///negative regulation of somatostatin secretion 16369 16369 'Irs3' mRNA 286 273 206 6.86 6.45 5.24 2.88 2.65 2.41 6.183333333 2.646666667 138 124 112 255 124.6666667 6.42E-08 -1.039569057 "04022///cGMP-PKG signaling pathway+++04068///FoxO signaling pathway+++04140///Autophagy - animal+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04930///Type II diabetes mellitus+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease" GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005158///insulin receptor binding+++GO:0043548///phosphatidylinositol 3-kinase binding GO:0008286///insulin receptor signaling pathway 16371 16371 'Irx1' mRNA 28 19 22 0.7 0.47 0.51 0.47 0.38 0.68 0.56 0.51 23 18 31 23 24 0.944592509 0.048697849 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030182///neuron differentiation+++GO:0048468///cell development+++GO:0072086///specification of loop of Henle identity+++GO:0072272///proximal/distal pattern formation involved in metanephric nephron development" 16372 16372 'Irx2' mRNA 1855 1939 1450 31.83 31.67 26.76 5.04 4.84 5.02 30.08666667 4.966666667 352 325 335 1748 337.3333333 9.56E-119 -2.380130214 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030182///neuron differentiation+++GO:0048468///cell development+++GO:0072086///specification of loop of Henle identity+++GO:0072272///proximal/distal pattern formation involved in metanephric nephron development" 16373 16373 'Irx3' mRNA 176 204 56 4.2 4.79 1.42 2.22 1.93 2.85 3.47 2.333333333 107 91 133 145.3333333 110.3333333 0.333049476 -0.386988891 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030424///axon "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001656///metanephros development+++GO:0001822///kidney development+++GO:0003165///Purkinje myocyte development+++GO:0003167///atrioventricular bundle cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007498///mesoderm development+++GO:0030182///neuron differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0060932///His-Purkinje system cell differentiation+++GO:0072047///proximal/distal pattern formation involved in nephron development+++GO:0072086///specification of loop of Henle identity+++GO:0097009///energy homeostasis+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:1903598///positive regulation of gap junction assembly" 16391 16391 'Irf9' mRNA 2983 3208 3115 69.68 73.81 77.65 68.22 73.67 68.87 73.71333333 70.25333333 3381 3540 3276 3102 3399 0.126066009 0.119802106 04217///Necroptosis+++04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032606///type I interferon production" 16392 16392 'Isl1' mRNA 952 941 883 20.98 20.42 20.64 5.35 4.92 5.16 20.68 5.143333333 279 251 261 925.3333333 263.6666667 2.41E-63 -1.822898406 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0030331///estrogen receptor binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0003007///heart morphogenesis+++GO:0003139///secondary heart field specification+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003266///regulation of secondary heart field cardioblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021524///visceral motor neuron differentiation+++GO:0021559///trigeminal nerve development+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0031016///pancreas development+++GO:0031103///axon regeneration+++GO:0031290///retinal ganglion cell axon guidance+++GO:0031333///negative regulation of protein complex assembly+++GO:0032024///positive regulation of insulin secretion+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035066///positive regulation of histone acetylation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043388///positive regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment+++GO:0048665///neuron fate specification+++GO:0048762///mesenchymal cell differentiation+++GO:0048880///sensory system development+++GO:0048935///peripheral nervous system neuron development+++GO:0048936///peripheral nervous system neuron axonogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060037///pharyngeal system development+++GO:0060379///cardiac muscle cell myoblast differentiation+++GO:0060384///innervation+++GO:0060413///atrial septum morphogenesis+++GO:0060913///cardiac cell fate determination+++GO:0060931///sinoatrial node cell development+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071657///positive regulation of granulocyte colony-stimulating factor production+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1901258///positive regulation of macrophage colony-stimulating factor production" 16396 16396 'Itch' mRNA 1232 1299 1266 12.53 13.02 13.73 13.64 12.34 13.48 13.09333333 13.15333333 1541 1359 1472 1265.666667 1457.333333 0.031541138 0.190178957 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0045236///CXCR chemokine receptor binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990763///arrestin family protein binding GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0002669///positive regulation of T cell anergy+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0035519///protein K29-linked ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0046329///negative regulation of JNK cascade+++GO:0046642///negative regulation of alpha-beta T cell proliferation+++GO:0050687///negative regulation of defense response to virus+++GO:0051607///defense response to virus+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0090085///regulation of protein deubiquitination+++GO:2000646///positive regulation of receptor catabolic process 16398 16398 'Itga2' mRNA 41 32 38 0.3 0.23 0.3 0.59 0.51 0.67 0.276666667 0.59 92 77 101 37 90 8.58E-05 1.268202206 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04611///Platelet activation+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0034666///integrin alpha2-beta1 complex+++GO:0042995///cell projection+++GO:0043679///axon terminus+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0001540///amyloid-beta binding+++GO:0005178///integrin binding+++GO:0005518///collagen binding+++GO:0038064///collagen receptor activity+++GO:0043236///laminin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0098639///collagen binding involved in cell-matrix adhesion "GO:0001666///response to hypoxia+++GO:0002687///positive regulation of leukocyte migration+++GO:0006929///substrate-dependent cell migration+++GO:0006971///hypotonic response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007565///female pregnancy+++GO:0008283///cell proliferation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0014070///response to organic cyclic compound+++GO:0014075///response to amine+++GO:0014850///response to muscle activity+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030879///mammary gland development+++GO:0031346///positive regulation of cell projection organization+++GO:0031589///cell-substrate adhesion+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033343///positive regulation of collagen binding+++GO:0033591///response to L-ascorbic acid+++GO:0033627///cell adhesion mediated by integrin+++GO:0038065///collagen-activated signaling pathway+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0043388///positive regulation of DNA binding+++GO:0043589///skin morphogenesis+++GO:0045184///establishment of protein localization+++GO:0045727///positive regulation of translation+++GO:0045785///positive regulation of cell adhesion+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0048041///focal adhesion assembly+++GO:0048333///mesodermal cell differentiation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050927///positive regulation of positive chemotaxis+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0070365///hepatocyte differentiation+++GO:0071107///response to parathyroid hormone+++GO:0071260///cellular response to mechanical stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071407///cellular response to organic cyclic compound" 16399 16399 'Itga2b' mRNA 253 237 258 4.01 3.69 4.34 4.02 4.65 4.78 4.013333333 4.483333333 292 330 336 249.3333333 319.3333333 0.040197477 0.344656294 04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding+++GO:0070051///fibrinogen binding GO:0002687///positive regulation of leukocyte migration+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0070527///platelet aggregation 16400 16400 'Itga3' mRNA 1526 1613 1539 16.82 17.5 17.98 29.09 27.82 27.38 17.43333333 28.09666667 3030 2838 2765 1559.333333 2877.666667 5.83E-37 0.871530443 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0031527///filopodium membrane+++GO:0034667///integrin alpha3-beta1 complex+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0071944///cell periphery+++GO:0097060///synaptic membrane+++GO:1990812///growth cone filopodium GO:0001968///fibronectin binding+++GO:0002020///protease binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0019904///protein domain specific binding+++GO:0043236///laminin binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity GO:0001764///neuron migration+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0007507///heart development+++GO:0007610///behavior+++GO:0007613///memory+++GO:0010628///positive regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030324///lung development+++GO:0030510///regulation of BMP signaling pathway+++GO:0031345///negative regulation of cell projection organization+++GO:0034698///response to gonadotropin+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035640///exploration behavior+++GO:0042493///response to drug+++GO:0043588///skin development+++GO:0048333///mesodermal cell differentiation+++GO:0060135///maternal process involved in female pregnancy+++GO:0072006///nephron development+++GO:0097062///dendritic spine maintenance+++GO:0097205///renal filtration+++GO:1903078///positive regulation of protein localization to plasma membrane 16401 16401 'Itga4' mRNA 151.63 151.66 206.25 0.89 0.89 1.3 3.68 3.39 3.29 1.026666667 3.453333333 735.59 638.8 632.28 169.8466667 668.89 1.99E-36 1.961082421 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04640///Hematopoietic cell lineage+++04670///Leukocyte transendothelial migration+++04672///Intestinal immune network for IgA production+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05140///Leishmaniasis+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0034669///integrin alpha4-beta7 complex+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome GO:0001968///fibronectin binding+++GO:0003823///antigen binding+++GO:0019960///C-X3-C chemokine binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:1990405///protein antigen binding GO:0001974///blood vessel remodeling+++GO:0002687///positive regulation of leukocyte migration+++GO:0003366///cell-matrix adhesion involved in ameboidal cell migration+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007507///heart development+++GO:0016477///cell migration+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035987///endodermal cell differentiation+++GO:0043113///receptor clustering+++GO:0050901///leukocyte tethering or rolling+++GO:0050904///diapedesis+++GO:0060324///face development+++GO:0060385///axonogenesis involved in innervation+++GO:0060485///mesenchyme development+++GO:0060710///chorio-allantoic fusion+++GO:0061032///visceral serous pericardium development+++GO:0071345///cellular response to cytokine stimulus+++GO:0072678///T cell migration+++GO:0090074///negative regulation of protein homodimerization activity+++GO:0098609///cell-cell adhesion+++GO:0098657///import into cell+++GO:0140039///cell-cell adhesion in response to extracellular stimulus+++GO:1903039///positive regulation of leukocyte cell-cell adhesion+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1904646///cellular response to amyloid-beta+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1990138///neuron projection extension+++GO:1990771///clathrin-dependent extracellular exosome endocytosis+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000406///positive regulation of T cell migration 16402 16402 'Itga5' mRNA 292 332 319 3.56 3.98 4.12 18.51 18.2 16.34 3.886666667 17.68333333 1749 1680 1496 314.3333333 1641.666667 2.52E-119 2.372145619 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05133///Pertussis+++05135///Yersinia infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0034674///integrin alpha5-beta1 complex+++GO:0045202///synapse GO:0005154///epidermal growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding "GO:0007044///cell-substrate junction assembly+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007565///female pregnancy+++GO:0007613///memory+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0023035///CD40 signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0031589///cell-substrate adhesion+++GO:0033627///cell adhesion mediated by integrin+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035987///endodermal cell differentiation+++GO:0045765///regulation of angiogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:2000811///negative regulation of anoikis" 16403 16403 'Itga6' mRNA 914 835 748 8.08 7.25 7.01 14.12 11.77 13.52 7.446666667 13.13666667 1841 1498 1706 832.3333333 1681.666667 1.24E-27 1.003625618 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030056///hemidesmosome+++GO:0030175///filopodium+++GO:0034676///integrin alpha6-beta4 complex+++GO:0045178///basal part of cell GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0031994///insulin-like growth factor I binding+++GO:0038132///neuregulin binding+++GO:0043236///laminin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0010668///ectodermal cell differentiation+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:0031589///cell-substrate adhesion+++GO:0031668///cellular response to extracellular stimulus+++GO:0033627///cell adhesion mediated by integrin+++GO:0035878///nail development+++GO:0042327///positive regulation of phosphorylation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0043589///skin morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046847///filopodium assembly+++GO:0050873///brown fat cell differentiation+++GO:0050900///leukocyte migration+++GO:0071407///cellular response to organic cyclic compound+++GO:0098609///cell-cell adhesion+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 16404 16404 'Itga7' mRNA 488.86 582.02 464.96 6.01 7.05 6.23 7.84 6.34 7.5 6.43 7.226666667 710.88 579 675.73 511.9466667 655.2033333 0.005751502 0.346149505 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005927///muscle tendon junction+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031594///neuromuscular junction+++GO:0034677///integrin alpha7-beta1 complex+++GO:0042383///sarcolemma GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0043236///laminin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035987///endodermal cell differentiation+++GO:0048514///blood vessel morphogenesis 16407 16407 'Itgae' mRNA 15 10 5 0.21 0.14 0.07 1.08 1.05 1.02 0.14 1.05 89 84 81 10 84.66666667 8.53E-13 3.077301555 04810///Regulation of actin cytoskeleton GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway 16408 16408 'Itgal' mRNA 86 87 106 0.88 0.87 1.15 1.72 1.91 1.9 0.966666667 1.843333333 194 210 207 93 203.6666667 2.01E-07 1.115778917 04015///Rap1 signaling pathway+++04514///Cell adhesion molecules+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05144///Malaria+++05150///Staphylococcus aureus infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05323///Rheumatoid arthritis+++05416///Viral myocarditis GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034687///integrin alphaL-beta2 complex GO:0030369///ICAM-3 receptor activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding GO:0002291///T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0022407///regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0035683///memory T cell extravasation+++GO:0042102///positive regulation of T cell proliferation+++GO:0043113///receptor clustering+++GO:0050798///activated T cell proliferation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0098609///cell-cell adhesion 16409 16409 'Itgam' mRNA 150 153 158 1.72 1.72 1.92 26.92 24.88 25.41 1.786666667 25.73666667 2707 2444 2475 153.6666667 2542 0 4.035385967 04015///Rap1 signaling pathway+++04145///Phagosome+++04514///Cell adhesion molecules+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05146///Amoebiasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034688///integrin alphaM-beta2 complex+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0001846///opsonin binding+++GO:0001851///complement component C3b binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0031072///heat shock protein binding+++GO:0038024///cargo receptor activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0001774///microglial cell activation+++GO:0001781///neutrophil apoptotic process+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006412///translation+++GO:0006898///receptor-mediated endocytosis+++GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0014005///microglia development+++GO:0030593///neutrophil chemotaxis+++GO:0030900///forebrain development+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033554///cellular response to stress+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0045123///cellular extravasation+++GO:0045963///negative regulation of dopamine metabolic process+++GO:0050798///activated T cell proliferation+++GO:0060376///positive regulation of mast cell differentiation+++GO:0061756///leukocyte adhesion to vascular endothelial cell+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0097190///apoptotic signaling pathway+++GO:0097242///amyloid-beta clearance+++GO:0098609///cell-cell adhesion+++GO:0110090///positive regulation of hippocampal neuron apoptotic process+++GO:0150062///complement-mediated synapse pruning+++GO:0150064///vertebrate eye-specific patterning+++GO:1901216///positive regulation of neuron death+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:1904151///positive regulation of microglial cell mediated cytotoxicity+++GO:1905114///cell surface receptor signaling pathway involved in cell-cell signaling+++GO:2000363///positive regulation of prostaglandin-E synthase activity" 16410 16410 'Itgav' mRNA 1690 1660 1236 12.4 11.92 9.61 14.47 14.7 14.12 11.31 14.43 2254 2244 2154 1528.666667 2217.333333 4.72E-09 0.530828411 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04810///Regulation of actin cytoskeleton+++04919///Thyroid hormone signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031258///lamellipodium membrane+++GO:0031527///filopodium membrane+++GO:0031528///microvillus membrane+++GO:0032587///ruffle membrane+++GO:0034683///integrin alphav-beta3 complex+++GO:0034684///integrin alphav-beta5 complex+++GO:0034685///integrin alphav-beta6 complex+++GO:0034686///integrin alphav-beta8 complex+++GO:0035867///alphav-beta3 integrin-IGF-1-IGF1R complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex GO:0001846///opsonin binding+++GO:0001968///fibronectin binding+++GO:0002020///protease binding+++GO:0005080///protein kinase C binding+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005245///voltage-gated calcium channel activity+++GO:0017134///fibroblast growth factor binding+++GO:0019960///C-X3-C chemokine binding+++GO:0031994///insulin-like growth factor I binding+++GO:0038132///neuregulin binding+++GO:0046872///metal ion binding+++GO:0050431///transforming growth factor beta binding+++GO:0050840///extracellular matrix binding+++GO:1990430///extracellular matrix protein binding GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009566///fertilization+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010888///negative regulation of lipid storage+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031589///cell-substrate adhesion+++GO:0032369///negative regulation of lipid transport+++GO:0032490///detection of molecule of bacterial origin+++GO:0033627///cell adhesion mediated by integrin+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035262///gonad morphogenesis+++GO:0035987///endodermal cell differentiation+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0042110///T cell activation+++GO:0043277///apoptotic cell clearance+++GO:0043542///endothelial cell migration+++GO:0045124///regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0046718///viral entry into host cell+++GO:0048041///focal adhesion assembly+++GO:0050748///negative regulation of lipoprotein metabolic process+++GO:0050764///regulation of phagocytosis+++GO:0050919///negative chemotaxis+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0060707///trophoblast giant cell differentiation+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0071604///transforming growth factor beta production+++GO:0071731///response to nitric oxide+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1901388///regulation of transforming growth factor beta activation+++GO:1902533///positive regulation of intracellular signal transduction+++GO:1905598///negative regulation of low-density lipoprotein receptor activity+++GO:2000536///negative regulation of entry of bacterium into host cell+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 16411 16411 'Itgax' mRNA 10 7 14 0.13 0.09 0.2 4.97 3.93 4.26 0.14 4.386666667 419.93 331.19 347.11 10.33333333 366.0766667 1.19E-59 5.12934029 04610///Complement and coagulation cascades+++04810///Regulation of actin cytoskeleton+++05152///Tuberculosis GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030335///positive regulation of cell migration+++GO:0031643///positive regulation of myelination+++GO:0034113///heterotypic cell-cell adhesion+++GO:0045766///positive regulation of angiogenesis+++GO:0050798///activated T cell proliferation+++GO:0051607///defense response to virus+++GO:1905956///positive regulation of endothelial tube morphogenesis 16412 16412 'Itgb1' mRNA 3195 3516 2345 41.02 44.4 31.94 63.29 77.65 73.17 39.12 71.37 5674 6800 6353 3018.666667 6275.666667 4.80E-26 1.054207212 04015///Rap1 signaling pathway+++04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0001669///acrosomal vesicle+++GO:0001726///ruffle+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0030175///filopodium+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032587///ruffle membrane+++GO:0034665///integrin alpha1-beta1 complex+++GO:0034666///integrin alpha2-beta1 complex+++GO:0034667///integrin alpha3-beta1 complex+++GO:0034674///integrin alpha5-beta1 complex+++GO:0034677///integrin alpha7-beta1 complex+++GO:0034679///integrin alpha9-beta1 complex+++GO:0034680///integrin alpha10-beta1 complex+++GO:0034681///integrin alpha11-beta1 complex+++GO:0035748///myelin sheath abaxonal region+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097060///synaptic membrane+++GO:0097386///glial cell projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099699///integral component of synaptic membrane GO:0001968///fibronectin binding+++GO:0002020///protease binding+++GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0019960///C-X3-C chemokine binding+++GO:0038023///signaling receptor activity+++GO:0043236///laminin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding+++GO:0051393///alpha-actinin binding+++GO:0098639///collagen binding involved in cell-matrix adhesion+++GO:1990782///protein tyrosine kinase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000132///establishment of mitotic spindle orientation+++GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001894///tissue homeostasis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008354///germ cell migration+++GO:0008542///visual learning+++GO:0010710///regulation of collagen catabolic process+++GO:0010763///positive regulation of fibroblast migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021943///formation of radial glial scaffolds+++GO:0023035///CD40 signaling pathway+++GO:0030030///cell projection organization+++GO:0030032///lamellipodium assembly+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0031345///negative regulation of cell projection organization+++GO:0031589///cell-substrate adhesion+++GO:0031623///receptor internalization+++GO:0032594///protein transport within lipid bilayer+++GO:0033627///cell adhesion mediated by integrin+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043149///stress fiber assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0045214///sarcomere organization+++GO:0045596///negative regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045807///positive regulation of endocytosis+++GO:0048333///mesodermal cell differentiation+++GO:0048675///axon extension+++GO:0048738///cardiac muscle tissue development+++GO:0048813///dendrite morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050901///leukocyte tethering or rolling+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051951///positive regulation of glutamate uptake involved in transmission of nerve impulse+++GO:0055007///cardiac muscle cell differentiation+++GO:0070830///bicellular tight junction assembly+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071711///basement membrane organization+++GO:0090303///positive regulation of wound healing+++GO:0150003///regulation of spontaneous synaptic transmission+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000811///negative regulation of anoikis 16413 16413 'Itgb1bp1' mRNA 731.79 726.1 752.73 27.77 27.11 31.95 38.44 39.74 37.97 28.94333333 38.71666667 1130.58 1116.47 1106.17 736.8733333 1117.74 2.40E-10 0.588566123 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030027///lamellipodium+++GO:0034451///centriolar satellite+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0005092///GDP-dissociation inhibitor activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding GO:0001525///angiogenesis+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0006469///negative regulation of protein kinase activity+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007219///Notch signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010764///negative regulation of fibroblast migration+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0031214///biomineral tissue development+++GO:0032091///negative regulation of protein binding+++GO:0032148///activation of protein kinase B activity+++GO:0033622///integrin activation+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0035148///tube formation+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043087///regulation of GTPase activity+++GO:0043113///receptor clustering+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051451///myoblast migration+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051781///positive regulation of cell division+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0072659///protein localization to plasma membrane+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0097746///regulation of blood vessel diameter+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:2001044///regulation of integrin-mediated signaling pathway 16414 16414 'Itgb2' mRNA 98 134 98 1.88 2.53 2.02 58.83 57.39 57.4 2.143333333 57.87333333 3528 3361 3332 110 3407 0 4.942920044 04015///Rap1 signaling pathway+++04145///Phagosome+++04390///Hippo signaling pathway+++04514///Cell adhesion molecules+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05144///Malaria+++05146///Amoebiasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05166///Human T-cell leukemia virus 1 infection+++05323///Rheumatoid arthritis+++05416///Viral myocarditis GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034687///integrin alphaL-beta2 complex+++GO:0034688///integrin alphaM-beta2 complex+++GO:0043235///receptor complex+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0099568///cytoplasmic region GO:0001540///amyloid-beta binding+++GO:0001851///complement component C3b binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030369///ICAM-3 receptor activity+++GO:0031072///heat shock protein binding+++GO:0038023///signaling receptor activity+++GO:0038024///cargo receptor activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding "GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006898///receptor-mediated endocytosis+++GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007568///aging+++GO:0016477///cell migration+++GO:0030101///natural killer cell activation+++GO:0030593///neutrophil chemotaxis+++GO:0031623///receptor internalization+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033627///cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0043113///receptor clustering+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0043542///endothelial cell migration+++GO:0045123///cellular extravasation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050798///activated T cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0097242///amyloid-beta clearance+++GO:0098609///cell-cell adhesion+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1990266///neutrophil migration" 16415 16415 'Itgb2l' mRNA 2 4 9 0.04 0.11 0.18 0.04 0 0.03 0.11 0.023333333 2 0 1 5 1 0.179616651 -2.370902795 04015///Rap1 signaling pathway+++04145///Phagosome+++04390///Hippo signaling pathway+++04514///Cell adhesion molecules+++04610///Complement and coagulation cascades+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++05134///Legionellosis+++05140///Leishmaniasis+++05144///Malaria+++05146///Amoebiasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05166///Human T-cell leukemia virus 1 infection+++05323///Rheumatoid arthritis+++05416///Viral myocarditis GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0034687///integrin alphaL-beta2 complex+++GO:0044853///plasma membrane raft+++GO:0099568///cytoplasmic region GO:0001540///amyloid-beta binding+++GO:0005178///integrin binding+++GO:0019901///protein kinase binding+++GO:0030369///ICAM-3 receptor activity+++GO:0031072///heat shock protein binding+++GO:0038023///signaling receptor activity+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0016477///cell migration+++GO:0030101///natural killer cell activation+++GO:0030593///neutrophil chemotaxis+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033627///cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0043113///receptor clustering+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0043542///endothelial cell migration+++GO:0045123///cellular extravasation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0098609///cell-cell adhesion+++GO:1990266///neutrophil migration 16416 16416 'Itgb3' mRNA 225 210 208 2.07 1.9 2.03 1.22 1.27 1.2 2 1.23 153 156 146 214.3333333 151.6666667 0.00702154 -0.510460619 04015///Rap1 signaling pathway+++04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04640///Hematopoietic cell lineage+++04810///Regulation of actin cytoskeleton+++04919///Thyroid hormone signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031258///lamellipodium membrane+++GO:0031527///filopodium membrane+++GO:0031528///microvillus membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0034679///integrin alpha9-beta1 complex+++GO:0034683///integrin alphav-beta3 complex+++GO:0035866///alphav-beta3 integrin-PKCalpha complex+++GO:0035867///alphav-beta3 integrin-IGF-1-IGF1R complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex+++GO:0098978///glutamatergic synapse+++GO:0099699///integral component of synaptic membrane GO:0001968///fibronectin binding+++GO:0002020///protease binding+++GO:0003756///protein disulfide isomerase activity+++GO:0005080///protein kinase C binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0017134///fibroblast growth factor binding+++GO:0019899///enzyme binding+++GO:0019960///C-X3-C chemokine binding+++GO:0031994///insulin-like growth factor I binding+++GO:0038132///neuregulin binding+++GO:0042802///identical protein binding+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0050839///cell adhesion molecule binding+++GO:0050840///extracellular matrix binding+++GO:0070051///fibrinogen binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002687///positive regulation of leukocyte migration+++GO:0007044///cell-substrate junction assembly+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010763///positive regulation of fibroblast migration+++GO:0010888///negative regulation of lipid storage+++GO:0014909///smooth muscle cell migration+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016477///cell migration+++GO:0030168///platelet activation+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0031589///cell-substrate adhesion+++GO:0032147///activation of protein kinase activity+++GO:0032369///negative regulation of lipid transport+++GO:0032880///regulation of protein localization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033627///cell adhesion mediated by integrin+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0043277///apoptotic cell clearance+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045780///positive regulation of bone resorption+++GO:0046718///viral entry into host cell+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048858///cell projection morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050748///negative regulation of lipoprotein metabolic process+++GO:0050919///negative chemotaxis+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051611///regulation of serotonin uptake+++GO:0060548///negative regulation of cell death+++GO:0061097///regulation of protein tyrosine kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070527///platelet aggregation+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1900731///positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway+++GO:1903053///regulation of extracellular matrix organization+++GO:1905598///negative regulation of low-density lipoprotein receptor activity+++GO:2000406///positive regulation of T cell migration 16418 16418 'Eif6' mRNA 1417 1416 1416 56.04 55.23 59.41 92.44 95.37 90.82 56.89333333 92.87666667 2685 2703 2552 1416.333333 2646.666667 2.27E-35 0.889668656 03008///Ribosome biogenesis in eukaryotes "GO:0005634///nucleus+++GO:0005638///lamin filament+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0030687///preribosome, large subunit precursor" GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding+++GO:0043023///ribosomal large subunit binding GO:0000054///ribosomal subunit export from nucleus+++GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA+++GO:0006110///regulation of glycolytic process+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0007229///integrin-mediated signaling pathway+++GO:0032868///response to insulin+++GO:0035195///gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042304///regulation of fatty acid biosynthetic process+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045727///positive regulation of translation+++GO:1902626///assembly of large subunit precursor of preribosome+++GO:2000377///regulation of reactive oxygen species metabolic process 16419 16419 'Itgb5' mRNA 1224 1225 1158 26.68 25.8 26.65 35.57 33.72 36.39 26.37666667 35.22666667 1863 1714 1847 1202.333333 1808 1.25E-14 0.576842078 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05205///Proteoglycans in cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031252///cell leading edge+++GO:0034684///integrin alphav-beta5 complex+++GO:0043235///receptor complex+++GO:0098978///glutamatergic synapse+++GO:0099699///integral component of synaptic membrane GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0016477///cell migration+++GO:0033627///cell adhesion mediated by integrin+++GO:0035987///endodermal cell differentiation+++GO:0043149///stress fiber assembly+++GO:0090136///epithelial cell-cell adhesion 16420 16420 'Itgb6' mRNA 150 125 147 1.7 1.41 1.8 2.25 1.76 1.69 1.636666667 1.9 227 174 164 140.6666667 188.3333333 0.075383075 0.404172712 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034685///integrin alphav-beta6 complex+++GO:0043235///receptor complex GO:0005178///integrin binding+++GO:0038023///signaling receptor activity GO:0000902///cell morphogenesis+++GO:0002534///cytokine production involved in inflammatory response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0009611///response to wounding+++GO:0009615///response to virus+++GO:0010467///gene expression+++GO:0016477///cell migration+++GO:0033627///cell adhesion mediated by integrin+++GO:0042060///wound healing+++GO:0043129///surfactant homeostasis+++GO:0043588///skin development+++GO:0048286///lung alveolus development+++GO:0055091///phospholipid homeostasis+++GO:0060022///hard palate development+++GO:0060348///bone development+++GO:0060395///SMAD protein signal transduction+++GO:0060435///bronchiole development+++GO:0061520///Langerhans cell differentiation+++GO:0070166///enamel mineralization+++GO:0071479///cellular response to ionizing radiation+++GO:0071604///transforming growth factor beta production+++GO:1901388///regulation of transforming growth factor beta activation 16421 16421 'Itgb7' mRNA 362 382 361 7.51 7.79 7.95 4.59 5.11 4.79 7.75 4.83 255 277 258 368.3333333 263.3333333 7.29E-04 -0.495072786 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04672///Intestinal immune network for IgA production+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05202///Transcriptional misregulation in cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034669///integrin alpha4-beta7 complex+++GO:0043235///receptor complex GO:0005178///integrin binding+++GO:0038023///signaling receptor activity+++GO:0050839///cell adhesion molecule binding GO:0003366///cell-matrix adhesion involved in ameboidal cell migration+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0016477///cell migration+++GO:0033627///cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043113///receptor clustering+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0072678///T cell migration 16423 16423 'Cd47' mRNA 3830 3929 3631 99.46 100.58 100.88 129.02 124.65 129.44 100.3066667 127.7033333 5571 5277 5424 3796.666667 5424 4.83E-21 0.503332961 04512///ECM-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome GO:0005515///protein binding+++GO:0070053///thrombospondin receptor activity+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion+++GO:0098632///cell-cell adhesion mediator activity GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0008228///opsonization+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0016477///cell migration+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0032649///regulation of interferon-gamma production+++GO:0032653///regulation of interleukin-10 production+++GO:0032655///regulation of interleukin-12 production+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035696///monocyte extravasation+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0050729///positive regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation+++GO:0051496///positive regulation of stress fiber assembly+++GO:0070487///monocyte aggregation+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071349///cellular response to interleukin-12+++GO:0098609///cell-cell adhesion+++GO:1904669///ATP export+++GO:1905450///negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:2000439///positive regulation of monocyte extravasation 16425 16425 'Itih2' mRNA 1428 1499 1490 25.06 25.88 27.73 72.97 74.14 71.92 26.22333333 73.01 4785 4749 4567 1472.333333 4700.333333 2.77E-138 1.661989326 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030212///hyaluronan metabolic process 16426 16426 'Itih3' mRNA 30 73 81 0.56 1.39 1.66 2.55 2.49 2.56 1.203333333 2.533333333 154 145 146 61.33333333 148.3333333 9.01E-05 1.253208027 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030212///hyaluronan metabolic process 16427 16427 'Itih4' mRNA 74 88 79 1.28 1.5 1.46 15.75 15.67 17.16 1.413333333 16.19333333 1046 1017 1104 80.33333333 1055.666667 5.13E-158 3.70515101 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005540///hyaluronic acid binding+++GO:0030414///peptidase inhibitor activity GO:0006953///acute-phase response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030212///hyaluronan metabolic process+++GO:0034097///response to cytokine 16428 16428 'Itk' mRNA 6 3 3 0.08 0.04 0.05 0.2 0.2 0.23 0.056666667 0.21 18 18 14 4 16.66666667 0.015675967 2.050608861 04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04670///Leukocyte transendothelial migration GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0001819///positive regulation of cytokine production+++GO:0001865///NK T cell differentiation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007202///activation of phospholipase C activity+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032609///interferon-gamma production+++GO:0032633///interleukin-4 production+++GO:0035556///intracellular signal transduction+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0046629///gamma-delta T cell activation+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway 16430 16430 'Stt3a' mRNA 3178 3208 3358 29.06 28.84 32.57 38.62 39.92 39.5 30.15666667 39.34666667 4863 4912 4819 3248 4864.666667 6.17E-17 0.569134782 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035000///oligosaccharyltransferase III complex "GO:0004576///oligosaccharyl transferase activity+++GO:0004579///dolichyl-diphosphooligosaccharide-protein glycotransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0043686///co-translational protein modification+++GO:0043687///post-translational protein modification 16431 16431 'Itm2a' mRNA 1763 1863 1918 63.06 65.7 72.78 50.09 60.7 56.92 67.18 55.90333333 1609 1903 1769 1848 1760.333333 0.47562508 -0.082302019 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding GO:0002317///plasma cell differentiation+++GO:0002377///immunoglobulin production+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process 16432 16432 'Itm2b' mRNA 82010 83620 79562 2632.51 2645.44 2709.38 2102.1 2126.14 2117.3 2662.443333 2115.18 75266 74305 73364 81730.66667 74311.66667 0.001580879 -0.148992085 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 16434 16434 'Itpa' mRNA 1106 1136 1046 56.46 57.33 56.61 76.24 76.61 70.32 56.8 74.39 1709 1677 1526 1096 1637.333333 1.71E-12 0.567997836 00230///Purine metabolism+++00983///Drug metabolism - other enzymes GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004551///nucleotide diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0035870///dITP diphosphatase activity+++GO:0036218///dTTP diphosphatase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity GO:0006193///ITP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0009204///deoxyribonucleoside triphosphate catabolic process+++GO:0051276///chromosome organization 16438 16438 'Itpr1' mRNA 2952 2845 2722 15.84 15.01 15.53 11.57 11 11.9 15.46 11.49 2486 2282 2464 2839.666667 2410.666667 2.17E-04 -0.248053052 "04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis" GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030868///smooth endoplasmic reticulum membrane+++GO:0031088///platelet dense granule membrane+++GO:0031094///platelet dense tubular network+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse "GO:0005216///ion channel activity+++GO:0005220///inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0015278///calcium-release channel activity+++GO:0019855///calcium channel inhibitor activity+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0070679///inositol 1,4,5 trisphosphate binding+++GO:0098695///inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels" GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006915///apoptotic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009791///post-embryonic development+++GO:0010976///positive regulation of neuron projection development+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0042045///epithelial fluid transport+++GO:0043065///positive regulation of apoptotic process+++GO:0048016///inositol phosphate-mediated signaling+++GO:0050849///negative regulation of calcium-mediated signaling+++GO:0050882///voluntary musculoskeletal movement+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051928///positive regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070588///calcium ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0097421///liver regeneration+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1901215///negative regulation of neuron death+++GO:2000347///positive regulation of hepatocyte proliferation 16439 16439 'Itpr2' mRNA 1598 1772 1513 8.29 8.66 8.08 6.34 6.69 6.85 8.343333333 6.626666667 1467 1455 1488 1627.666667 1470 0.060023494 -0.156661522 "04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05205///Proteoglycans in cancer" GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0043209///myelin sheath+++GO:0043235///receptor complex "GO:0005216///ion channel activity+++GO:0005220///inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015278///calcium-release channel activity+++GO:0035091///phosphatidylinositol binding+++GO:0044325///ion channel binding+++GO:0070679///inositol 1,4,5 trisphosphate binding+++GO:0097110///scaffold protein binding" GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034220///ion transmembrane transport+++GO:0048016///inositol phosphate-mediated signaling+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071361///cellular response to ethanol 16440 16440 'Itpr3' mRNA 723 799 658 5.63 6.08 5.63 4.95 4.42 4.9 5.78 4.756666667 782 647 709 726.6666667 712.6666667 0.796181878 -0.038537142 "04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05205///Proteoglycans in cancer" GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043235///receptor complex+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse "GO:0000822///inositol hexakisphosphate binding+++GO:0005216///ion channel activity+++GO:0005220///inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015278///calcium-release channel activity+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0043533///inositol 1,3,4,5 tetrakisphosphate binding+++GO:0044877///protein-containing complex binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007613///memory+++GO:0034220///ion transmembrane transport+++GO:0048016///inositol phosphate-mediated signaling+++GO:0050913///sensory perception of bitter taste+++GO:0050916///sensory perception of sweet taste+++GO:0050917///sensory perception of umami taste+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0060291///long-term synaptic potentiation+++GO:0060402///calcium ion transport into cytosol+++GO:0070588///calcium ion transmembrane transport+++GO:0071320///cellular response to cAMP 16443 16443 'Itsn1' mRNA 1162.04 1232.17 864.99 10.1 10.53 7.84 7.78 8.8 8.85 9.49 8.476666667 965.71 1059.44 1055.79 1086.4 1026.98 0.537419712 -0.085452854 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0055037///recycling endosome+++GO:0097440///apical dendrite+++GO:0097708///intracellular vesicle+++GO:0098833///presynaptic endocytic zone+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019209///kinase activator activity+++GO:0046872///metal ion binding+++GO:0060090///molecular adaptor activity+++GO:0070064///proline-rich region binding GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0033674///positive regulation of kinase activity+++GO:0034613///cellular protein localization+++GO:0035556///intracellular signal transduction+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0050790///regulation of catalytic activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060124///positive regulation of growth hormone secretion+++GO:0060999///positive regulation of dendritic spine development+++GO:0150007///clathrin-dependent synaptic vesicle endocytosis+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:2001288///positive regulation of caveolin-mediated endocytosis 16447 16447 'Ivl' mRNA 23 18 16 0.68 0.53 0.5 2.76 3.02 2.86 0.57 2.88 107 114 107 19 109.3333333 7.40E-14 2.516165058 GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0010224///response to UV-B+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization 16449 16449 'Jag1' mRNA 911 923 814 8.53 8.29 7.99 3.01 3.11 3.33 8.27 3.15 375 382 405 882.6666667 387.3333333 2.13E-30 -1.19778642 01522///Endocrine resistance+++04330///Notch signaling pathway+++04371///Apelin signaling pathway+++04658///Th1 and Th2 cell differentiation+++04668///TNF signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0045177///apical part of cell GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0048018///receptor ligand activity GO:0001953///negative regulation of cell-matrix adhesion+++GO:0001974///blood vessel remodeling+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0002456///T cell mediated immunity+++GO:0003184///pulmonary valve morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0007154///cell communication+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0032495///response to muramyl dipeptide+++GO:0035909///aorta morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0043010///camera-type eye development+++GO:0045596///negative regulation of cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:0060411///cardiac septum morphogenesis+++GO:0061073///ciliary body morphogenesis+++GO:0061156///pulmonary artery morphogenesis+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0061314///Notch signaling involved in heart development+++GO:0061444///endocardial cushion cell development+++GO:0062043///positive regulation of cardiac epithelial to mesenchymal transition+++GO:0072006///nephron development+++GO:0072015///glomerular visceral epithelial cell development+++GO:0072017///distal tubule development+++GO:0072070///loop of Henle development+++GO:0097150///neuronal stem cell population maintenance+++GO:2000737///negative regulation of stem cell differentiation 16450 16450 'Jag2' mRNA 774 792 789 8.59 8.48 9.15 2.28 2.32 2.5 8.74 2.366666667 235 238 254 785 242.3333333 3.90E-47 -1.708107228 01522///Endocrine resistance+++04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05224///Breast cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001501///skeletal system development+++GO:0001701///in utero embryonic development+++GO:0001709///cell fate determination+++GO:0003016///respiratory system process+++GO:0007154///cell communication+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007605///sensory perception of sound+++GO:0009912///auditory receptor cell fate commitment+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030217///T cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042492///gamma-delta T cell differentiation+++GO:0045061///thymic T cell selection+++GO:0045747///positive regulation of Notch signaling pathway+++GO:1990134///epithelial cell apoptotic process involved in palatal shelf morphogenesis 16451 16451 'Jak1' mRNA 2729.94 2820.05 2757.41 28.14 29.03 30.73 36.73 37.91 34.65 29.3 36.43 3872.04 3946.18 3594.52 2769.133333 3804.246667 5.17E-11 0.44611659 01521///EGFR tyrosine kinase inhibitor resistance+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04550///Signaling pathways regulating pluripotency of stem cells+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05212///Pancreatic cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005131///growth hormone receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034112///positive regulation of homotypic cell-cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0036016///cellular response to interleukin-3+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0046677///response to antibiotic+++GO:0098761///cellular response to interleukin-7+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904894///positive regulation of STAT cascade 16452 16452 'Jak2' mRNA 543 550 487 4.34 4.77 4.92 4.5 4.62 5.26 4.676666667 4.793333333 550 551 571 526.6666667 557.3333333 0.615074028 0.071892565 "01521///EGFR tyrosine kinase inhibitor resistance+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04725///Cholinergic synapse+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0045121///membrane raft+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005131///growth hormone receptor binding+++GO:0005143///interleukin-12 receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0020037///heme binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0033130///acetylcholine receptor binding+++GO:0035401///histone kinase activity (H3-Y41 specific)+++GO:0042169///SH2 domain binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043560///insulin receptor substrate binding+++GO:0046872///metal ion binding+++GO:0051428///peptide hormone receptor binding GO:0000186///activation of MAPKK activity+++GO:0001774///microglial cell activation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007259///JAK-STAT cascade+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009755///hormone-mediated signaling pathway+++GO:0010572///positive regulation of platelet activation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030099///myeloid cell differentiation+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031103///axon regeneration+++GO:0031959///mineralocorticoid receptor signaling pathway+++GO:0032024///positive regulation of insulin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033194///response to hydroperoxide+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034050///host programmed cell death induced by symbiont+++GO:0034612///response to tumor necrosis factor+++GO:0035166///post-embryonic hemopoiesis+++GO:0035409///histone H3-Y41 phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0036016///cellular response to interleukin-3+++GO:0038065///collagen-activated signaling pathway+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042976///activation of Janus kinase activity+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043392///negative regulation of DNA binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045822///negative regulation of heart contraction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046677///response to antibiotic+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050867///positive regulation of cell activation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060396///growth hormone receptor signaling pathway+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0060399///positive regulation of growth hormone receptor signaling pathway+++GO:0060548///negative regulation of cell death+++GO:0061180///mammary gland epithelium development+++GO:0070671///response to interleukin-12+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0097012///response to granulocyte macrophage colony-stimulating factor+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097296///activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901731///positive regulation of platelet aggregation+++GO:1902728///positive regulation of growth factor dependent skeletal muscle satellite cell proliferation+++GO:1904037///positive regulation of epithelial cell apoptotic process+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000273///positive regulation of signaling receptor activity+++GO:2001235///positive regulation of apoptotic signaling pathway 16453 16453 'Jak3' mRNA 194 215.72 194.68 2.79 3.06 2.98 8.88 8.51 6.94 2.943333333 8.11 712 665.45 543 201.4666667 640.15 3.73E-32 1.658955027 04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05223///Non-small cell lung cancer+++05340///Primary immunodeficiency GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002731///negative regulation of dendritic cell cytokine production+++GO:0006468///protein phosphorylation+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0035556///intracellular signal transduction+++GO:0035771///interleukin-4-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0045087///innate immune response+++GO:0045221///negative regulation of FasL biosynthetic process+++GO:0045626///negative regulation of T-helper 1 cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048535///lymph node development+++GO:0050868///negative regulation of T cell activation+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051928///positive regulation of calcium ion transport+++GO:0070232///regulation of T cell apoptotic process+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0070669///response to interleukin-2+++GO:0070670///response to interleukin-4+++GO:0070672///response to interleukin-15+++GO:0071104///response to interleukin-9+++GO:0071345///cellular response to cytokine stimulus+++GO:2000670///positive regulation of dendritic cell apoptotic process+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 16456 16456 'F11r' mRNA 3256 3375 3405 73.13 74.64 81.13 82.35 83.35 82.06 76.3 82.58666667 4217 4168 4068 3345.333333 4151 8.43E-06 0.298101082 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0070160///tight junction GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0042803///protein homodimerization activity GO:0001817///regulation of cytokine production+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0008360///regulation of cell shape+++GO:0009314///response to radiation+++GO:0030154///cell differentiation+++GO:0030855///epithelial cell differentiation+++GO:0031032///actomyosin structure organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034260///negative regulation of GTPase activity+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035683///memory T cell extravasation+++GO:0043547///positive regulation of GTPase activity+++GO:0045777///positive regulation of blood pressure+++GO:0050892///intestinal absorption+++GO:0051493///regulation of cytoskeleton organization+++GO:0051497///negative regulation of stress fiber assembly+++GO:0071260///cellular response to mechanical stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0090559///regulation of membrane permeability+++GO:0098609///cell-cell adhesion+++GO:1901731///positive regulation of platelet aggregation+++GO:1902396///protein localization to bicellular tight junction+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000810///regulation of bicellular tight junction assembly 16467 16467 'Atcay' mRNA 42 37 31 0.61 0.53 0.47 0.08 0.01 0.05 0.536666667 0.046666667 6 1 4 36.66666667 3.666666667 1.17E-06 -3.334591278 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031966///mitochondrial membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse GO:0004309///exopolyphosphatase activity+++GO:0019894///kinesin binding GO:0006798///polyphosphate catabolic process+++GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0031175///neuron projection development+++GO:0032880///regulation of protein localization+++GO:0048311///mitochondrion distribution+++GO:2000212///negative regulation of glutamate metabolic process 16468 16468 'Jarid2' mRNA 887.78 882.58 784.35 6.06 5.68 5.37 5.3 4.82 5.71 5.703333333 5.276666667 934.52 854.92 985.58 851.57 925.0066667 0.329174395 0.108995987 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0035097///histone methyltransferase complex+++GO:0035098///ESC/E(Z) complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0032452///histone demethylase activity+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0043130///ubiquitin binding+++GO:0061649///ubiquitin modification-dependent histone binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001889///liver development+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0030154///cell differentiation+++GO:0031061///negative regulation of histone methylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0042127///regulation of cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048863///stem cell differentiation+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:1902682///protein localization to nuclear pericentric heterochromatin+++GO:1990830///cellular response to leukemia inhibitory factor" 16469 16469 'Jrk' mRNA 310 270 283 2.98 2.56 2.89 2.1 1.87 1.67 2.81 1.88 251 219 194 287.6666667 221.3333333 0.026021338 -0.391860503 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003729///mRNA binding GO:0090263///positive regulation of canonical Wnt signaling pathway 16470 16470 'Ush1g' mRNA 328 320 387 5.64 5.41 7.06 0.99 0.89 1.17 6.036666667 1.016666667 66 58 76 345 66.66666667 2.29E-32 -2.388931203 GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body GO:0005515///protein binding+++GO:0030507///spectrin binding+++GO:0042802///identical protein binding GO:0007605///sensory perception of sound+++GO:0042472///inner ear morphogenesis+++GO:0045494///photoreceptor cell maintenance+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0060113///inner ear receptor cell differentiation+++GO:0060122///inner ear receptor cell stereocilium organization 16475 16475 'Ajuba' mRNA 556.25 566 347.91 8.64 8.64 5.73 4.67 6.54 6.5 7.67 5.903333333 346 473.85 467 490.0533333 428.95 0.354202939 -0.190665059 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0045294///alpha-catenin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030032///lamellipodium assembly+++GO:0030334///regulation of cell migration+++GO:0031047///gene silencing by RNA+++GO:0031328///positive regulation of cellular biosynthetic process+++GO:0031334///positive regulation of protein complex assembly+++GO:0033673///negative regulation of kinase activity+++GO:0033674///positive regulation of kinase activity+++GO:0034613///cellular protein localization+++GO:0035195///gene silencing by miRNA+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035331///negative regulation of hippo signaling+++GO:0043087///regulation of GTPase activity+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046474///glycerophospholipid biosynthetic process+++GO:0048041///focal adhesion assembly+++GO:1900037///regulation of cellular response to hypoxia+++GO:2000637///positive regulation of gene silencing by miRNA" 16476 16476 'Jun' mRNA 638 591 649 10.95 9.98 11.82 37.02 34.7 36.74 10.91666667 36.15333333 2482 2272 2385 626 2379.666667 2.12E-114 1.912389377 01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04024///cAMP signaling pathway+++04137///Mitophagy - animal+++04210///Apoptosis+++04214///Apoptosis - fly+++04310///Wnt signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04530///Tight junction+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05224///Breast cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0035976///transcription factor AP-1 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070412///R-SMAD binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001774///microglial cell activation+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001889///liver development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0003151///outflow tract morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007568///aging+++GO:0007612///learning+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009314///response to radiation+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0010634///positive regulation of epithelial cell migration+++GO:0014070///response to organic cyclic compound+++GO:0030224///monocyte differentiation+++GO:0031103///axon regeneration+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0034097///response to cytokine+++GO:0034614///cellular response to reactive oxygen species+++GO:0035026///leading edge cell differentiation+++GO:0035994///response to muscle stretch+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043922///negative regulation by host of viral transcription+++GO:0043923///positive regulation by host of viral transcription+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0051365///cellular response to potassium ion starvation+++GO:0051591///response to cAMP+++GO:0051726///regulation of cell cycle+++GO:0051899///membrane depolarization+++GO:0060395///SMAD protein signal transduction+++GO:0061029///eyelid development in camera-type eye+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071276///cellular response to cadmium ion+++GO:0071277///cellular response to calcium ion+++GO:0072740///cellular response to anisomycin+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:2000144///positive regulation of DNA-templated transcription, initiation" 16477 16477 'Junb' mRNA 606 612 551 18.93 18.84 18.26 65.39 72.87 69.62 18.67666667 69.29333333 2406 2617 2479 589.6666667 2500.666667 6.04E-143 2.074955093 "04380///Osteoclast differentiation+++04668///TNF signaling pathway+++04935///Growth hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0035976///transcription factor AP-1 complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001570///vasculogenesis+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001829///trophectodermal cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0009987///cellular process+++GO:0030316///osteoclast differentiation+++GO:0033687///osteoblast proliferation+++GO:0042127///regulation of cell proliferation+++GO:0045597///positive regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046697///decidualization+++GO:0051726///regulation of cell cycle+++GO:0060136///embryonic process involved in female pregnancy+++GO:0060716///labyrinthine layer blood vessel development+++GO:0071277///cellular response to calcium ion" 16478 16478 'Jund' mRNA 280 305 123 5.36 5.75 2.5 2.95 3.72 4.14 4.536666667 3.603333333 177 218 241 236 212 0.66275058 -0.146925988 "04010///MAPK signaling pathway+++04380///Osteoclast differentiation+++04657///IL-17 signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0035976///transcription factor AP-1 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002076///osteoblast development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007568///aging+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0009612///response to mechanical stimulus+++GO:0014070///response to organic cyclic compound+++GO:0032496///response to lipopolysaccharide+++GO:0042127///regulation of cell proliferation+++GO:0043032///positive regulation of macrophage activation+++GO:0043434///response to peptide hormone+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0071277///cellular response to calcium ion" 16480 16480 'Jup' mRNA 4956 4787 4830 80.27 76.45 83.28 67.65 64.41 65.5 80 65.85333333 4776 4460 4481 4857.666667 4572.333333 0.135621143 -0.100475893 05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005916///fascia adherens+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014704///intercalated disc+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0032993///protein-DNA complex+++GO:0071665///gamma-catenin-TCF7L2 complex GO:0003713///transcription coactivator activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0035257///nuclear hormone receptor binding+++GO:0044877///protein-containing complex binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0050839///cell adhesion molecule binding+++GO:0106006///microtubule cortical anchor activity GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002159///desmosome assembly+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0042127///regulation of cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043588///skin development+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050982///detection of mechanical stimulus+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0071681///cellular response to indole-3-methanol+++GO:0072659///protein localization to plasma membrane+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential 16485 16485 'Kcna1' mRNA 5072 5104 4526 29.67 29.34 28.08 14.18 11.88 13.1 29.03 13.05333333 2791 2285 2499 4900.666667 2525 1.64E-46 -0.968171316 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0033270///paranode region of axon+++GO:0034705///potassium channel complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0044224///juxtaparanode region of axon+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1905030///voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001964///startle response+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006937///regulation of muscle contraction+++GO:0007405///neuroblast proliferation+++GO:0007420///brain development+++GO:0010644///cell communication by electrical coupling+++GO:0010960///magnesium ion homeostasis+++GO:0019228///neuronal action potential+++GO:0021766///hippocampus development+++GO:0023041///neuronal signal transduction+++GO:0034613///cellular protein localization+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050905///neuromuscular process+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0050976///detection of mechanical stimulus involved in sensory perception of touch+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071286///cellular response to magnesium ion+++GO:0071805///potassium ion transmembrane transport+++GO:0099505///regulation of presynaptic membrane potential+++GO:1903818///positive regulation of voltage-gated potassium channel activity 16490 16490 'Kcna2' mRNA 891 981 917 4.01 4.33 4.38 2.25 1.88 2.15 4.24 2.093333333 581 472 535 929.6666667 529.3333333 5.73E-15 -0.825791839 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031258///lamellipodium membrane+++GO:0032809///neuronal cell body membrane+++GO:0033010///paranodal junction+++GO:0034705///potassium channel complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043194///axon initial segment+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0044224///juxtaparanode region of axon+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015271///outward rectifier potassium channel activity+++GO:0019894///kinesin binding "GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0014059///regulation of dopamine secretion+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0021633///optic nerve structural organization+++GO:0034765///regulation of ion transmembrane transport+++GO:0045188///regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane" 16491 16491 'Kcna3' mRNA 5 4 6 0.14 0.11 0.18 0.18 0.31 0.57 0.143333333 0.353333333 7 12 22 5 13.66666667 0.12266598 1.438189892 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0044305///calyx of Held+++GO:0045121///membrane raft+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015271///outward rectifier potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16492 16492 'Kcna4' mRNA 340 359 361.09 2.31 2.5 2.4 0.51 0.43 0.45 2.403333333 0.463333333 95 79 81 353.3633333 85 3.67E-31 -2.069766847 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032279///asymmetric synapse+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0030955///potassium ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16493 16493 'Kcna5' mRNA 9 12 3 0.16 0.22 0.06 0.21 0.16 0.07 0.146666667 0.146666667 13 10 4 8 9 0.879214745 0.173835075 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0034705///potassium channel complex+++GO:0045121///membrane raft+++GO:0046691///intracellular canaliculus+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015271///outward rectifier potassium channel activity+++GO:0019870///potassium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0051393///alpha-actinin binding+++GO:0086087///voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization+++GO:0086089///voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization+++GO:0086090///voltage-gated potassium channel activity involved in SA node cell action potential repolarization+++GO:0097110///scaffold protein binding GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007219///Notch signaling pathway+++GO:0009612///response to mechanical stimulus+++GO:0010033///response to organic substance+++GO:0019229///regulation of vasoconstriction+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042542///response to hydrogen peroxide+++GO:0043266///regulation of potassium ion transport+++GO:0043267///negative regulation of potassium ion transport+++GO:0051259///protein complex oligomerization+++GO:0051260///protein homooligomerization+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0055093///response to hyperoxia+++GO:0060081///membrane hyperpolarization+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0071805///potassium ion transmembrane transport+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086050///membrane repolarization during bundle of His cell action potential+++GO:0086052///membrane repolarization during SA node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2000288///positive regulation of myoblast proliferation 16494 16494 'Kcna6' mRNA 109 137 124 0.98 1.21 1.18 0.66 0.64 0.51 1.123333333 0.603333333 83 80 66 123.3333333 76.33333333 0.007227896 -0.70468363 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0034705///potassium channel complex+++GO:0043679///axon terminus GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16495 16495 'Kcna7' mRNA 35 23 11 0.54 0.35 0.18 0.07 0.11 0.04 0.356666667 0.073333333 5 8 3 23 5.333333333 0.006768241 -2.10207768 GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16497 16497 'Kcnab1' mRNA 2855 2978 2873 52.88 54.23 56.34 3.95 4.7 3.51 54.48333333 4.053333333 250 291 214 2902 251.6666667 4.58E-277 -3.539069987 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032839///dendrite cytoplasm+++GO:0034705///potassium channel complex+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0044224///juxtaparanode region of axon+++GO:1990635///proximal dendrite GO:0004033///aldo-keto reductase (NADP) activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0016491///oxidoreductase activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0070402///NADPH binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007611///learning or memory+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903817///negative regulation of voltage-gated potassium channel activity 16498 16498 'Kcnab2' mRNA 917.12 915.88 746.09 13.41 12.84 11.58 8.61 8.57 8.85 12.61 8.676666667 658.19 645.87 655.17 859.6966667 653.0766667 8.18E-05 -0.404956441 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031091///platelet alpha granule+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0034705///potassium channel complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043194///axon initial segment+++GO:0043679///axon terminus+++GO:0044224///juxtaparanode region of axon+++GO:0045202///synapse+++GO:1990031///pinceau fiber GO:0004033///aldo-keto reductase (NADP) activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0016491///oxidoreductase activity+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047834///D-threo-aldose 1-dehydrogenase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008015///blood circulation+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0050905///neuromuscular process+++GO:0055085///transmembrane transport+++GO:0070995///NADPH oxidation+++GO:0071805///potassium ion transmembrane transport+++GO:0098900///regulation of action potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:2000008///regulation of protein localization to cell surface 16499 16499 'Kcnab3' mRNA 90 101 84 1.97 2.18 1.95 1.75 1.35 1.02 2.033333333 1.373333333 92 69 52 91.66666667 71 0.250717656 -0.381093031 GO:0005737///cytoplasm+++GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane GO:0004033///aldo-keto reductase (NADP) activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:0047834///D-threo-aldose 1-dehydrogenase activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1901379///regulation of potassium ion transmembrane transport 16500 16500 'Kcnb1' mRNA 577 494 526 2.7 2.27 2.61 0.53 0.39 0.45 2.526666667 0.456666667 130 94 108 532.3333333 110.6666667 5.68E-46 -2.280738959 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0000149///SNARE binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015271///outward rectifier potassium channel activity+++GO:0044325///ion channel binding+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding GO:0001508///action potential+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007215///glutamate receptor signaling pathway+++GO:0010701///positive regulation of norepinephrine secretion+++GO:0031669///cellular response to nutrient levels+++GO:0033605///positive regulation of catecholamine secretion+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042593///glucose homeostasis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0046676///negative regulation of insulin secretion+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071333///cellular response to glucose stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0097623///potassium ion export across plasma membrane+++GO:0098900///regulation of action potential+++GO:1900454///positive regulation of long-term synaptic depression+++GO:2000671///regulation of motor neuron apoptotic process 16502 16502 'Kcnc1' mRNA 10 2 0 0.07 0.02 0 0 0.01 0.02 0.03 0.01 0 2 2 4 1.333333333 0.470054289 -1.556633522 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0032589///neuron projection membrane+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0044325///ion channel binding+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007420///brain development+++GO:0009636///response to toxic substance+++GO:0009642///response to light intensity+++GO:0010996///response to auditory stimulus+++GO:0014075///response to amine+++GO:0021549///cerebellum development+++GO:0021759///globus pallidus development+++GO:0034765///regulation of ion transmembrane transport+++GO:0034767///positive regulation of ion transmembrane transport+++GO:0035690///cellular response to drug+++GO:0035864///response to potassium ion+++GO:0051260///protein homooligomerization+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0071774///response to fibroblast growth factor+++GO:0071805///potassium ion transmembrane transport+++GO:0099505///regulation of presynaptic membrane potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity+++GO:1990089///response to nerve growth factor 16504 16504 'Kcnc3' mRNA 127 130 61 1.28 1.23 0.59 0.42 0.35 0.28 1.033333333 0.35 51 43 34 106 42.66666667 1.40E-04 -1.312182412 05017///Spinocerebellar ataxia GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031594///neuromuscular junction+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0046928///regulation of neurotransmitter secretion+++GO:0051260///protein homooligomerization+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16506 16506 'Kcnd1' mRNA 223 199 196 2.78 2.5 2.79 0.71 0.74 0.7 2.69 0.716666667 68 67 62 206 65.66666667 1.51E-14 -1.660795857 GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005250///A-type (transient outward) potassium channel activity+++GO:0005267///potassium channel activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16508 16508 'Kcnd2' mRNA 180.02 154.62 142.38 0.1 0.09 0.08 0.06 0.04 0.05 0.09 0.05 100.97 75.47 95.39 159.0066667 90.61 3.86E-04 -0.82922983 04726///Serotonergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0032809///neuronal cell body membrane+++GO:0034705///potassium channel complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005250///A-type (transient outward) potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:1905030///voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001508///action potential+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0034765///regulation of ion transmembrane transport+++GO:0045475///locomotor rhythm+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071456///cellular response to hypoxia+++GO:0071805///potassium ion transmembrane transport+++GO:0086001///cardiac muscle cell action potential 16509 16509 'Kcne1' mRNA 5571 5871 5249 100.37 104.07 100.38 53.39 53.66 50.47 101.6066667 52.50666667 3426 3369 3131 5563.666667 3308.666667 9.73E-39 -0.760363693 04261///Adrenergic signaling in cardiomyocytes GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0045121///membrane raft GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0031433///telethonin binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0002070///epithelial cell maturation+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0008584///male gonad development+++GO:0021750///vestibular nucleus development+++GO:0033363///secretory granule organization+++GO:0034765///regulation of ion transmembrane transport+++GO:0060047///heart contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071320///cellular response to cAMP+++GO:0071468///cellular response to acidic pH+++GO:0071482///cellular response to light stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086009///membrane repolarization+++GO:0086011///membrane repolarization during action potential+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1903818///positive regulation of voltage-gated potassium channel activity 16510 16510 'Kcnh1' mRNA 1 2 12 0.01 0.01 0.09 0.03 0.04 0.01 0.036666667 0.026666667 5 6 1 5 4 0.839445158 -0.379773137 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031901///early endosome membrane+++GO:0034705///potassium channel complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098839///postsynaptic density membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0030551///cyclic nucleotide binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0071889///14-3-3 protein binding+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1902936///phosphatidylinositol bisphosphate binding GO:0001964///startle response+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042127///regulation of cell proliferation+++GO:0042391///regulation of membrane potential+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0055085///transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071805///potassium ion transmembrane transport+++GO:0099505///regulation of presynaptic membrane potential+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 16511 16511 'Kcnh2' mRNA 211 210 228 3.29 2.97 3.62 0.82 0.99 1.25 3.293333333 1.02 57 68 85 216.3333333 70 4.12E-13 -1.640641134 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:1902937///inward rectifier potassium channel complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005216///ion channel activity+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:0097110///scaffold protein binding+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization "GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035690///cellular response to drug+++GO:0042391///regulation of membrane potential+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060048///cardiac muscle contraction+++GO:0060306///regulation of membrane repolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086009///membrane repolarization+++GO:0086010///membrane depolarization during action potential+++GO:0086011///membrane repolarization during action potential+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:1990573///potassium ion import across plasma membrane" 16512 16512 'Kcnh3' mRNA 1 12 0 0.02 0.18 0 0.01 0.01 0.03 0.066666667 0.016666667 1 1 2 4.333333333 1.333333333 0.416528164 -1.66814335 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16513 16513 'Kcnj10' mRNA 2139 2168 1924 21.69 21.77 20.53 11.1 11.17 10.57 21.33 10.94666667 1278 1262 1182 2077 1240.666667 3.99E-25 -0.753447132 04971///Gastric acid secretion+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0044297///cell body+++GO:0097449///astrocyte projection+++GO:0097546///ciliary base+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0005102///signaling receptor binding+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007601///visual perception+++GO:0007628///adult walking behavior+++GO:0014003///oligodendrocyte development+++GO:0022010///central nervous system myelination+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0051930///regulation of sensory perception of pain+++GO:0051935///glutamate reuptake+++GO:0051938///L-glutamate import+++GO:0055075///potassium ion homeostasis+++GO:0060075///regulation of resting membrane potential+++GO:0060081///membrane hyperpolarization+++GO:0071805///potassium ion transmembrane transport+++GO:1905515///non-motile cilium assembly+++GO:1990573///potassium ion import across plasma membrane 16514 16514 'Kcnj11' mRNA 100 86 92 1.97 1.74 1.9 0.16 0.22 0.41 1.87 0.263333333 9 12 22 92.66666667 14.33333333 8.62E-12 -2.703434431 04911///Insulin secretion+++04929///GnRH secretion+++04930///Type II diabetes mellitus GO:0001669///acrosomal vesicle+++GO:0005635///nuclear envelope+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008282///inward rectifying potassium channel+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030673///axolemma+++GO:0042383///sarcolemma+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070852///cell body fiber GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0015272///ATP-activated inward rectifier potassium channel activity+++GO:0019829///cation-transporting ATPase activity+++GO:0030506///ankyrin binding+++GO:0030955///potassium ion binding+++GO:0031072///heat shock protein binding+++GO:0044325///ion channel binding GO:0002931///response to ischemia+++GO:0006006///glucose metabolic process+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0009410///response to xenobiotic stimulus+++GO:0032355///response to estradiol+++GO:0033198///response to ATP+++GO:0033574///response to testosterone+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042493///response to drug+++GO:0046676///negative regulation of insulin secretion+++GO:0050796///regulation of insulin secretion+++GO:0050877///nervous system process+++GO:0071316///cellular response to nicotine+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1990573///potassium ion import across plasma membrane+++GO:2001259///positive regulation of cation channel activity 16515 16515 'Kcnj12' mRNA 22 35 25 0.27 0.38 0.34 0.18 0.07 0.12 0.33 0.123333333 19 6 11 27.33333333 12 0.059441527 -1.203440064 04725///Cholinergic synapse+++04921///Oxytocin signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0031224///intrinsic component of membrane+++GO:0043025///neuronal cell body GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0030165///PDZ domain binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051289///protein homotetramerization+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16516 16516 'Kcnj15' mRNA 5 10 2 0.07 0.15 0.03 0.23 0.14 0.14 0.083333333 0.17 19 13 15 5.666666667 15.66666667 0.090766849 1.470435454 04971///Gastric acid secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16517 16517 'Kcnj16' mRNA 2854 2884 2833 42.59 42.34 44.87 16.14 15.38 14.37 43.26666667 15.29666667 1243 1156 1071 2857 1156.666667 4.98E-70 -1.317573516 04971///Gastric acid secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006885///regulation of pH+++GO:0010037///response to carbon dioxide+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16518 16518 'Kcnj2' mRNA 129 150 138 1.26 1.44 1.43 0.73 0.45 0.62 1.376666667 0.6 86 52 71 139 69.66666667 1.12E-04 -1.011694331 04725///Cholinergic synapse+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04971///Gastric acid secretion GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0031224///intrinsic component of membrane+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0097546///ciliary base "GO:0005216///ion channel activity+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0042802///identical protein binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization" GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0014861///regulation of skeletal muscle contraction via regulation of action potential+++GO:0015693///magnesium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0051289///protein homotetramerization+++GO:0055085///transmembrane transport+++GO:0055119///relaxation of cardiac muscle+++GO:0060306///regulation of membrane repolarization+++GO:0071260///cellular response to mechanical stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086001///cardiac muscle cell action potential+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086011///membrane repolarization during action potential+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090076///relaxation of skeletal muscle+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1905515///non-motile cilium assembly+++GO:1990573///potassium ion import across plasma membrane 16519 16519 'Kcnj3' mRNA 69 93 74 0.66 0.88 0.76 0.38 0.34 0.09 0.766666667 0.27 35 30 11 78.66666667 25.33333333 5.92E-05 -1.647005339 04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04929///GnRH secretion+++05032///Morphine addiction GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099056///integral component of presynaptic membrane "GO:0000166///nucleotide binding+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0015272///ATP-activated inward rectifier potassium channel activity+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0030955///potassium ion binding+++GO:0042277///peptide binding" GO:0001822///kidney development+++GO:0001894///tissue homeostasis+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0009791///post-embryonic development+++GO:0010467///gene expression+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0043066///negative regulation of apoptotic process+++GO:0051602///response to electrical stimulus+++GO:0070294///renal sodium ion absorption+++GO:0071286///cellular response to magnesium ion+++GO:0071805///potassium ion transmembrane transport+++GO:0072359///circulatory system development+++GO:1900128///regulation of G-protein activated inward rectifier potassium channel activity+++GO:1990573///potassium ion import across plasma membrane 16520 16520 'Kcnj4' mRNA 9 6 6 0.08 0.16 0.06 0.04 0 0 0.1 0.013333333 6 0 0 7 2 0.237865013 -1.838448822 04725///Cholinergic synapse+++04921///Oxytocin signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0030165///PDZ domain binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16521 16521 'Kcnj5' mRNA 0 8 0 0 0.1 0 0 0 0 0.033333333 0 0 0 0 2.666666667 0 0.246608217 -3.822208332 04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++04929///GnRH secretion+++05032///Morphine addiction GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0086089///voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:1990573///potassium ion import across plasma membrane 16522 16522 'Kcnj6' mRNA 127.98 131.84 75.45 1.12 0.92 0.67 0.12 0.01 0.1 0.903333333 0.076666667 15.08 4.3 10.12 111.7566667 9.833333333 2.08E-16 -3.526829068 04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04929///GnRH secretion+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099056///integral component of presynaptic membrane GO:0001965///G-protein alpha-subunit binding+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0015467///G-protein activated inward rectifier potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042403///thyroid hormone metabolic process+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16523 16523 'Kcnj8' mRNA 189 155 203 4.13 3.33 4.71 2.68 2.37 2.35 4.056666667 2.466666667 141 122 120 182.3333333 127.6666667 0.017860602 -0.532149544 04022///cGMP-PKG signaling pathway GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0008282///inward rectifying potassium channel+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030016///myofibril+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005524///ATP binding+++GO:0015272///ATP-activated inward rectifier potassium channel activity+++GO:0017098///sulfonylurea receptor binding+++GO:0019829///cation-transporting ATPase activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0001822///kidney development+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007507///heart development+++GO:0032496///response to lipopolysaccharide+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1990573///potassium ion import across plasma membrane 16524 16524 'Kcnj9' mRNA 13 18 8 0.18 0.25 0.12 0.1 0.09 0.16 0.183333333 0.116666667 8 7 13 13 9.333333333 0.615350007 -0.476780235 04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04929///GnRH secretion+++05032///Morphine addiction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099056///integral component of presynaptic membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0030165///PDZ domain binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 16525 16525 'Kcnk1' mRNA 2198 2316 2177 52.85 54.97 55.66 36.93 37.58 35.05 54.49333333 36.52 1753 1747 1619 2230.333333 1706.333333 4.49E-08 -0.397991068 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0034705///potassium channel complex+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0055037///recycling endosome+++GO:0097060///synaptic membrane+++GO:1902937///inward rectifier potassium channel complex GO:0005242///inward rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0022841///potassium ion leak channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0035094///response to nicotine+++GO:0035725///sodium ion transmembrane transport+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport 16526 16526 'Kcnk2' mRNA 844 906 746 13.99 14.83 13.33 2.02 2.11 2.38 14.05 2.17 141 143 160 832 148 2.35E-84 -2.49943572 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++04971///Gastric acid secretion GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0044305///calyx of Held+++GO:0097449///astrocyte projection GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015271///outward rectifier potassium channel activity+++GO:0019870///potassium channel inhibitor activity+++GO:0022841///potassium ion leak channel activity GO:0003231///cardiac ventricle development+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007613///memory+++GO:0009612///response to mechanical stimulus+++GO:0010942///positive regulation of cell death+++GO:0030322///stabilization of membrane potential+++GO:0042391///regulation of membrane potential+++GO:0048678///response to axon injury+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0071456///cellular response to hypoxia+++GO:0071805///potassium ion transmembrane transport+++GO:0090102///cochlea development+++GO:1900039///positive regulation of cellular response to hypoxia+++GO:2000279///negative regulation of DNA biosynthetic process 16527 16527 'Kcnk3' mRNA 4 6 5 0.06 0.08 0.08 0.02 0.01 0.05 0.073333333 0.026666667 2 1 4 5 2.333333333 0.471145999 -1.111790366 04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005252///open rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0008022///protein C-terminus binding+++GO:0022841///potassium ion leak channel activity+++GO:0044548///S100 protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007420///brain development+++GO:0009410///response to xenobiotic stimulus+++GO:0030322///stabilization of membrane potential+++GO:0034220///ion transmembrane transport+++GO:0042493///response to drug+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0071294///cellular response to zinc ion+++GO:0071456///cellular response to hypoxia+++GO:0071805///potassium ion transmembrane transport+++GO:0090102///cochlea development 16528 16528 'Kcnk4' mRNA 10 12 6 0.26 0.34 0.19 0.34 0.08 0.22 0.263333333 0.213333333 12 3 8 9.333333333 7.666666667 0.809547651 -0.292914859 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0034705///potassium channel complex+++GO:0036128///CatSper complex+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0003674///molecular_function+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0022841///potassium ion leak channel activity+++GO:0042802///identical protein binding+++GO:0097604///temperature-gated cation channel activity+++GO:0098782///mechanosensitived potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0007613///memory+++GO:0019233///sensory perception of pain+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0030322///stabilization of membrane potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0048240///sperm capacitation+++GO:0050951///sensory perception of temperature stimulus+++GO:0050976///detection of mechanical stimulus involved in sensory perception of touch+++GO:0071260///cellular response to mechanical stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071469///cellular response to alkaline pH+++GO:0071502///cellular response to temperature stimulus+++GO:0071805///potassium ion transmembrane transport 16529 16529 'Kcnk5' mRNA 220 242 232 3.53 3.85 3.98 3.52 3.17 3.45 3.786666667 3.38 250 221 238 231.3333333 236.3333333 0.936144366 0.017872192 04742///Taste transduction+++04974///Protein digestion and absorption GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane+++GO:1990573///potassium ion import across plasma membrane 16530 16530 'Kcnk7' mRNA 5.72 1.3 6.86 0.2 0.04 0.32 0.29 0.13 0.34 0.186666667 0.253333333 8.17 4.81 8.51 4.626666667 7.163333333 0.613174197 0.704012507 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0003073///regulation of systemic arterial blood pressure+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport 16531 16531 'Kcnma1' mRNA 729 694 567 5.61 5.14 4.21 0.47 0.39 0.62 4.986666667 0.493333333 74 52 77 663.3333333 67.66666667 5.78E-86 -3.302026905 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion+++04924///Renin secretion+++04970///Salivary secretion+++04972///Pancreatic secretion GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0008076///voltage-gated potassium channel complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0003779///actin binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0060072///large conductance calcium-activated potassium channel activity+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006970///response to osmotic stress+++GO:0007268///chemical synaptic transmission+++GO:0007605///sensory perception of sound+++GO:0007623///circadian rhythm+++GO:0007628///adult walking behavior+++GO:0009268///response to pH+++GO:0019228///neuronal action potential+++GO:0030007///cellular potassium ion homeostasis+++GO:0031960///response to corticosteroid+++GO:0032344///regulation of aldosterone metabolic process+++GO:0034220///ion transmembrane transport+++GO:0034465///response to carbon monoxide+++GO:0034765///regulation of ion transmembrane transport+++GO:0042311///vasodilation+++GO:0042391///regulation of membrane potential+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045475///locomotor rhythm+++GO:0045794///negative regulation of cell volume+++GO:0046541///saliva secretion+++GO:0048469///cell maturation+++GO:0050885///neuromuscular process controlling balance+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0060073///micturition+++GO:0060082///eye blink reflex+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0060087///relaxation of vascular smooth muscle+++GO:0071805///potassium ion transmembrane transport+++GO:0097746///regulation of blood vessel diameter+++GO:0099505///regulation of presynaptic membrane potential+++GO:1904348///negative regulation of small intestine smooth muscle contraction 16532 16532 'Kcnu1' mRNA 7 7 15 0.11 0.11 0.26 0.07 0.07 0.06 0.16 0.066666667 5 5 4 9.666666667 4.666666667 0.310911528 -1.081120158 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0060072///large conductance calcium-activated potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0022414///reproductive process+++GO:0034765///regulation of ion transmembrane transport+++GO:0050821///protein stabilization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 16533 16533 'Kcnmb1' mRNA 13 3 6 0.17 0.04 0.09 0.14 0.04 0.05 0.1 0.076666667 12 3 4 7.333333333 6.333333333 0.863090843 -0.234034712 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0015459///potassium channel regulator activity GO:0005513///detection of calcium ion+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007568///aging+++GO:0042311///vasodilation+++GO:0051592///response to calcium ion+++GO:0071361///cellular response to ethanol+++GO:0071456///cellular response to hypoxia+++GO:0071805///potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903413///cellular response to bile acid 16534 16534 'Kcnn4' mRNA 482 484 405 13.89 13.82 12.51 25 25.28 26.42 13.40666667 25.56666667 995 981 1019 457 998.3333333 2.14E-29 1.11849379 04911///Insulin secretion+++04929///GnRH secretion+++04970///Salivary secretion+++04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031982///vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0016286///small conductance calcium-activated potassium channel activity+++GO:0019903///protein phosphatase binding+++GO:0022894///Intermediate conductance calcium-activated potassium channel activity GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006816///calcium ion transport+++GO:0006820///anion transport+++GO:0006884///cell volume homeostasis+++GO:0030322///stabilization of membrane potential+++GO:0045332///phospholipid translocation+++GO:0046541///saliva secretion+++GO:0050714///positive regulation of protein secretion+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane 16535 16535 'Kcnq1' mRNA 3372 3519 3015 63.48 65.66 61.48 37.99 39.1 39.55 63.54 38.88 2305 2296 2289 3302 2296.666667 2.05E-17 -0.533039022 04261///Adrenergic signaling in cardiomyocytes+++04725///Cholinergic synapse+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04974///Protein digestion and absorption+++05110///Vibrio cholerae infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030133///transport vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034702///ion channel complex+++GO:0034705///potassium channel complex+++GO:0042383///sarcolemma+++GO:0042589///zymogen granule membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0097546///ciliary base+++GO:1990794///basolateral part of cell "GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008157///protein phosphatase 1 binding+++GO:0015271///outward rectifier potassium channel activity+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:0086089///voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization+++GO:0097110///scaffold protein binding+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization" GO:0001696///gastric acid secretion+++GO:0001698///gastrin-induced gastric acid secretion+++GO:0002027///regulation of heart rate+++GO:0006006///glucose metabolic process+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0007622///rhythmic behavior+++GO:0008217///regulation of blood pressure+++GO:0010460///positive regulation of heart rate+++GO:0010467///gene expression+++GO:0010629///negative regulation of gene expression+++GO:0015705///iodide transport+++GO:0016458///gene silencing+++GO:0030218///erythrocyte differentiation+++GO:0030644///cellular chloride ion homeostasis+++GO:0032409///regulation of transporter activity+++GO:0032868///response to insulin+++GO:0034765///regulation of ion transmembrane transport+++GO:0035094///response to nicotine+++GO:0035176///social behavior+++GO:0035690///cellular response to drug+++GO:0035934///corticosterone secretion+++GO:0042391///regulation of membrane potential+++GO:0042472///inner ear morphogenesis+++GO:0046676///negative regulation of insulin secretion+++GO:0048839///inner ear development+++GO:0050892///intestinal absorption+++GO:0050905///neuromuscular process+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060048///cardiac muscle contraction+++GO:0060117///auditory receptor cell development+++GO:0060306///regulation of membrane repolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0060453///regulation of gastric acid secretion+++GO:0060454///positive regulation of gastric acid secretion+++GO:0061337///cardiac conduction+++GO:0070293///renal absorption+++GO:0070294///renal sodium ion absorption+++GO:0071320///cellular response to cAMP+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0071871///response to epinephrine+++GO:0071872///cellular response to epinephrine stimulus+++GO:0071875///adrenergic receptor signaling pathway+++GO:0072347///response to anesthetic+++GO:0072359///circulatory system development+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086009///membrane repolarization+++GO:0086011///membrane repolarization during action potential+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090102///cochlea development+++GO:0097623///potassium ion export across plasma membrane+++GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1905150///regulation of voltage-gated sodium channel activity+++GO:1905515///non-motile cilium assembly+++GO:1990573///potassium ion import across plasma membrane 16536 16536 'Kcnq2' mRNA 0 0 1 0 0 0.02 0.04 0 0 0.006666667 0.013333333 2 0 0 0.333333333 0.666666667 0.863090843 0.855344965 04725///Cholinergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0033268///node of Ranvier+++GO:0043194///axon initial segment GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0030506///ankyrin binding+++GO:0047485///protein N-terminus binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0019226///transmission of nerve impulse+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0071805///potassium ion transmembrane transport 16538 16538 'Kcns1' mRNA 5 3 10 0.1 0.06 0.22 0.41 0.58 0.35 0.126666667 0.446666667 23 32 19 6 24.66666667 0.005430799 2.014195634 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015459///potassium channel regulator activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1902259///regulation of delayed rectifier potassium channel activity 16541 16541 'Napsa' mRNA 56 84 58 2.24 3.32 2.46 15.76 14.93 13.87 2.673333333 14.85333333 452 418 385 66 418.3333333 1.83E-45 2.654846725 04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0097208///alveolar lamellar body GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0043129///surfactant homeostasis 16542 16542 'Kdr' mRNA 1850 2009 2068 16.66 17.74 19.7 5.04 4.8 4.71 18.03333333 4.85 646 601 583 1975.666667 610 3.79E-77 -1.710205657 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0071944///cell periphery+++GO:0097443///sorting endosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0038085///vascular endothelial growth factor binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001936///regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001945///lymph vessel development+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003157///endocardium development+++GO:0003158///endothelium development+++GO:0003416///endochondral bone growth+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016239///positive regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032008///positive regulation of TOR signaling+++GO:0033674///positive regulation of kinase activity+++GO:0035162///embryonic hemopoiesis+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0042311///vasodilation+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043129///surfactant homeostasis+++GO:0043410///positive regulation of MAPK cascade+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045165///cell fate commitment+++GO:0045446///endothelial cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0048286///lung alveolus development+++GO:0048469///cell maturation+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048812///neuron projection morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0055074///calcium ion homeostasis+++GO:0060837///blood vessel endothelial cell differentiation+++GO:0061042///vascular wound healing+++GO:0061154///endothelial tube morphogenesis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090141///positive regulation of mitochondrial fission+++GO:1901532///regulation of hematopoietic progenitor cell differentiation+++GO:1903010///regulation of bone development+++GO:1904881///cellular response to hydrogen sulfide+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2001214///positive regulation of vasculogenesis 16543 16543 'Mdfic' mRNA 43 30 19 0.68 0.47 0.32 2.31 3.17 3.7 0.49 3.06 166 224 260 30.66666667 216.6666667 4.23E-22 2.819848956 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030332///cyclin binding+++GO:0030957///Tat protein binding "GO:0007257///activation of JUN kinase activity+++GO:0030111///regulation of Wnt signaling pathway+++GO:0042308///negative regulation of protein import into nucleus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046328///regulation of JNK cascade+++GO:0050434///positive regulation of viral transcription" 16548 16548 'Khk' mRNA 625 597 585 27.25 25.44 26.99 23.24 23.56 24.22 26.56 23.67333333 611 600 613 602.3333333 608 0.996468262 0.001909476 00051///Fructose and mannose metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004454///ketohexokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006000///fructose metabolic process+++GO:0009744///response to sucrose+++GO:0009749///response to glucose+++GO:0009750///response to fructose+++GO:0010043///response to zinc ion+++GO:0016310///phosphorylation+++GO:0032868///response to insulin+++GO:0046835///carbohydrate phosphorylation+++GO:0061624///fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate+++GO:0061625///glycolytic process through fructose-1-phosphate+++GO:0070873///regulation of glycogen metabolic process 16549 16549 'Khsrp' mRNA 538 545 254 7.26 7.24 3.64 4.82 4.72 5.01 6.046666667 4.85 411 393 414 445.6666667 406 0.609822222 -0.131135062 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043025///neuronal cell body "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003824///catalytic activity+++GO:0016208///AMP binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0005975///carbohydrate metabolic process+++GO:0005986///sucrose biosynthetic process+++GO:0006000///fructose metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006111///regulation of gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0008152///metabolic process+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0010586///miRNA metabolic process+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016311///dephosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0035690///cellular response to drug+++GO:0043488///regulation of mRNA stability+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045820///negative regulation of glycolytic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0051028///mRNA transport+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0071286///cellular response to magnesium ion+++GO:0071345///cellular response to cytokine stimulus+++GO:2000628///regulation of miRNA metabolic process" 16551 16551 'Kif11' mRNA 22.01 19.71 23 0.24 0.21 0.27 2.84 3.02 2.74 0.24 2.866666667 296.54 307.71 276.95 21.57333333 293.7333333 2.90E-49 3.767606049 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0032991///protein-containing complex+++GO:0072686///mitotic spindle "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0019901///protein kinase binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007100///mitotic centrosome separation+++GO:0046602///regulation of mitotic centrosome separation+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly 16552 16552 'Kif12' mRNA 0 3 0 0 0.07 0 0.04 0 0 0.023333333 0.013333333 2 0 0 1 0.666666667 0.886766534 -0.580494656 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0070062///extracellular exosome GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement 16553 16553 'Kif13a' mRNA 659 735 606 4.98 5.37 4.86 2.63 2.84 3.16 5.07 2.876666667 400 421 465 666.6666667 428.6666667 6.21E-08 -0.645437816 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0032588///trans-Golgi network membrane GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0006886///intracellular protein transport+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0032438///melanosome organization+++GO:0032465///regulation of cytokinesis+++GO:0035459///cargo loading into vesicle+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0051301///cell division+++GO:0072383///plus-end-directed vesicle transport along microtubule 16554 16554 'Kif13b' mRNA 2384 2444 2090 13.85 13.88 12.88 9.79 8.26 8.46 13.53666667 8.836666667 1932 1593 1632 2306 1719 5.82E-08 -0.434717017 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005902///microvillus+++GO:0030424///axon+++GO:0033270///paranode region of axon GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0071889///14-3-3 protein binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0050770///regulation of axonogenesis 16558 16558 'Kif16b' mRNA 1275 1312 1049 12.14 12.46 10.7 6.22 6.32 6.57 11.76666667 6.37 752 744 763 1212 753 6.01E-14 -0.694366999 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0045335///phagocytic vesicle "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0031267///small GTPase binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0001704///formation of primary germ layer+++GO:0001919///regulation of receptor recycling+++GO:0006895///Golgi to endosome transport+++GO:0007018///microtubule-based movement+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007492///endoderm development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0032801///receptor catabolic process+++GO:0045022///early endosome to late endosome transport+++GO:0071346///cellular response to interferon-gamma 16559 16559 'Kif17' mRNA 73 97 53 1.03 1.46 0.78 0.34 0.4 0.31 1.09 0.35 27 30 25 74.33333333 27.33333333 1.16E-04 -1.444584976 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0030425///dendrite+++GO:0030992///intraciliary transport particle B+++GO:0032391///photoreceptor connecting cilium+++GO:0032839///dendrite cytoplasm+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:1990075///periciliary membrane compartment "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007017///microtubule-based process+++GO:0007018///microtubule-based movement+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030030///cell projection organization+++GO:0031503///protein-containing complex localization+++GO:0042073///intraciliary transport+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex 16560 16560 'Kif1a' mRNA 4191 4399 3904 26.62 27.45 26.34 12.43 10.9 11.94 26.80333333 11.75666667 2250 1928 2095 4164.666667 2091 5.01E-55 -1.0053787 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098674///extrinsic component of neuronal dense core vesicle membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098992///neuronal dense core vesicle+++GO:0099012///neuronal dense core vesicle membrane+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0008089///anterograde axonal transport+++GO:0016192///vesicle-mediated transport+++GO:0022027///interkinetic nuclear migration+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0060998///regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0098840///protein transport along microtubule+++GO:0099519///dense core granule cytoskeletal transport+++GO:1990048///anterograde neuronal dense core vesicle transport+++GO:1990049///retrograde neuronal dense core vesicle transport 16561 16561 'Kif1b' mRNA 3702 3814 3349 20.78 21.03 20.23 16.31 14.1 15.32 20.68 15.24333333 3270 2767 2962 3621.666667 2999.666667 3.06E-05 -0.283040469 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0019900///kinase binding+++GO:0097110///scaffold protein binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0008089///anterograde axonal transport+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010628///positive regulation of gene expression+++GO:0010970///transport along microtubule+++GO:0016192///vesicle-mediated transport+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0032418///lysosome localization+++GO:0047497///mitochondrion transport along microtubule+++GO:1904647///response to rotenone+++GO:1990048///anterograde neuronal dense core vesicle transport+++GO:1990049///retrograde neuronal dense core vesicle transport+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990778///protein localization to cell periphery 16562 16562 'Kif1c' mRNA 214 210 191 2.04 1.88 1.94 2.3 2.34 2.33 1.953333333 2.323333333 287 271 278 205 278.6666667 0.008712751 0.432276046 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007018///microtubule-based movement+++GO:0016192///vesicle-mediated transport+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:1990048///anterograde neuronal dense core vesicle transport+++GO:1990049///retrograde neuronal dense core vesicle transport" 16563 16563 'Kif2a' mRNA 430.52 474.71 411.53 6.02 6.62 6.16 5.51 4.53 4.27 6.266666667 4.77 455.57 363.1 338.52 438.92 385.73 0.209343764 -0.198217054 04361///Axon regeneration GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0016604///nuclear body+++GO:0097228///sperm principal piece+++GO:0120103///centriolar subdistal appendage GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0000226///microtubule cytoskeleton organization+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly 16564 16564 'Kif21a' mRNA 3086.26 3218.69 2854.53 25.12 25.62 24.71 8.18 7.8 8.03 25.15 8.003333333 1186.91 1103.99 1134.64 3053.16 1141.846667 3.22E-103 -1.430379564 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0071532///ankyrin repeat binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement 16565 16565 'Kif21b' mRNA 27 22 34 0.16 0.12 0.21 0.6 0.73 0.82 0.163333333 0.716666667 121 142 159 27.66666667 140.6666667 2.16E-14 2.330778328 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement 16568 16568 'Kif3a' mRNA 2789 2868.74 2807 26.77 27.09 28.63 11.76 12.07 12.08 27.49666667 11.97 1396.14 1401 1389.08 2821.58 1395.406667 1.36E-49 -1.027996516 04340///Hedgehog signaling pathway GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0016939///kinesin II complex+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097470///ribbon synapse+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:0019903///protein phosphatase binding+++GO:0030507///spectrin binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0120170///intraciliary transport particle B binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001947///heart looping+++GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0008089///anterograde axonal transport+++GO:0008544///epidermis development+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010457///centriole-centriole cohesion+++GO:0015031///protein transport+++GO:0021542///dentate gyrus development+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021915///neural tube development+++GO:0030030///cell projection organization+++GO:0030900///forebrain development+++GO:0034454///microtubule anchoring at centrosome+++GO:0036334///epidermal stem cell homeostasis+++GO:0044458///motile cilium assembly+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060271///cilium assembly+++GO:0061351///neural precursor cell proliferation+++GO:0090316///positive regulation of intracellular protein transport+++GO:1902414///protein localization to cell junction+++GO:1905128///positive regulation of axo-dendritic protein transport+++GO:1905515///non-motile cilium assembly+++GO:2000771///positive regulation of establishment or maintenance of cell polarity regulating cell shape 16569 16569 'Kif3b' mRNA 425 440 338 4.01 4.08 3.39 4.2 3.97 3.94 3.826666667 4.036666667 512 473 465 401 483.3333333 0.056989357 0.261457341 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0016939///kinesin II complex+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0032839///dendrite cytoplasm+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0031267///small GTPase binding+++GO:0120170///intraciliary transport particle B binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0016192///vesicle-mediated transport+++GO:0032467///positive regulation of cytokinesis+++GO:0036372///opsin transport+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly+++GO:0090307///mitotic spindle assembly+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex 16570 16570 'Kif3c' mRNA 1333 1265 1177 10.28 9.59 9.63 6.28 6.25 6.5 9.833333333 6.343333333 937 911 940 1258.333333 929.3333333 1.23E-07 -0.447790981 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0035371///microtubule plus-end+++GO:0043025///neuronal cell body+++GO:0071598///neuronal ribonucleoprotein granule GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0010976///positive regulation of neuron projection development+++GO:0072384///organelle transport along microtubule 16571 16571 'Kif4' mRNA 4 9 8.26 0.05 0.1 0.1 1.66 1.47 1.33 0.083333333 1.486666667 164.47 142.26 130.79 7.086666667 145.84 4.61E-26 4.362501598 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030496///midbody GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0000281///mitotic cytokinesis+++GO:0007018///microtubule-based movement+++GO:0007052///mitotic spindle organization+++GO:0051256///mitotic spindle midzone assembly 16572 16572 'Kif5a' mRNA 655 654 578 6.36 6.18 5.8 1.16 1.01 0.91 6.113333333 1.026666667 148 128 117 629 131 4.10E-59 -2.274297656 04144///Endocytosis+++04728///Dopaminergic synapse+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05223///Non-small cell lung cancer GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0035253///ciliary rootlet+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0090724///central region of growth cone+++GO:0097440///apical dendrite+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007411///axon guidance+++GO:0016192///vesicle-mediated transport+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0048489///synaptic vesicle transport+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex+++GO:0099641///anterograde axonal protein transport+++GO:1990049///retrograde neuronal dense core vesicle transport 16573 16573 'Kif5b' mRNA 6816.81 7238.02 6823.97 59.98 62.6 63.68 54.29 49.05 53.89 62.08666667 52.41 7104.64 6272.77 6831.74 6959.6 6736.383333 0.399157104 -0.059809109 04144///Endocytosis+++04728///Dopaminergic synapse+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05223///Non-small cell lung cancer GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031982///vesicle+++GO:0032839///dendrite cytoplasm+++GO:0034451///centriolar satellite+++GO:0035253///ciliary rootlet+++GO:0043005///neuron projection+++GO:0043227///membrane-bounded organelle+++GO:0044295///axonal growth cone+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008432///JUN kinase binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:0099609///microtubule lateral binding+++GO:1990939///ATP-dependent microtubule motor activity" "GO:0006839///mitochondrial transport+++GO:0007017///microtubule-based process+++GO:0007018///microtubule-based movement+++GO:0007028///cytoplasm organization+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0021766///hippocampus development+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032418///lysosome localization+++GO:0035617///stress granule disassembly+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042391///regulation of membrane potential+++GO:0043268///positive regulation of potassium ion transport+++GO:0047496///vesicle transport along microtubule+++GO:0048489///synaptic vesicle transport+++GO:0051642///centrosome localization+++GO:0071346///cellular response to interferon-gamma+++GO:0072383///plus-end-directed vesicle transport along microtubule+++GO:0090316///positive regulation of intracellular protein transport+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex+++GO:0099641///anterograde axonal protein transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905152///positive regulation of voltage-gated sodium channel activity+++GO:1990049///retrograde neuronal dense core vesicle transport" 16574 16574 'Kif5c' mRNA 703 611 548 5.41 4.62 4.47 3.63 3.57 3.66 4.833333333 3.62 544 522 531 620.6666667 532.3333333 0.065198843 -0.230712354 04144///Endocytosis+++04728///Dopaminergic synapse+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05223///Non-small cell lung cancer GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0035253///ciliary rootlet+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0150034///distal axon+++GO:1904115///axon cytoplasm "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0034190///apolipoprotein receptor binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0046034///ATP metabolic process+++GO:0048489///synaptic vesicle transport+++GO:0051028///mRNA transport+++GO:0098963///dendritic transport of messenger ribonucleoprotein complex+++GO:0098964///anterograde dendritic transport of messenger ribonucleoprotein complex+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex+++GO:0099641///anterograde axonal protein transport 16576 16576 'Kif7' mRNA 85 129 97 0.99 1.49 1.41 0.98 1.28 0.91 1.296666667 1.056666667 84 112 84 103.6666667 93.33333333 0.655494996 -0.158387168 04340///Hedgehog signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0003279///cardiac septum development+++GO:0007018///microtubule-based movement+++GO:0035904///aorta development+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060976///coronary vasculature development 16578 16578 'Kif9' mRNA 1159 1180 1264 19.77 19.59 22.57 2.8 2.97 3.14 20.64333333 2.97 203 215 210 1201 209.3333333 2.19E-105 -2.534484571 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0031982///vesicle GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0022617///extracellular matrix disassembly+++GO:0071801///regulation of podosome assembly+++GO:1903008///organelle disassembly 16579 16579 'Kifap3' mRNA 1710 1847 1750 23.37 24.82 25.32 10.99 9.51 10.36 24.50333333 10.28666667 924 784 846 1769 851.3333333 8.18E-37 -1.06833793 GO:0000794///condensed nuclear chromosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005871///kinesin complex+++GO:0005876///spindle microtubule+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0016939///kinesin II complex+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:1990075///periciliary membrane compartment GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0019903///protein phosphatase binding+++GO:0120170///intraciliary transport particle B binding GO:0007017///microtubule-based process+++GO:0007018///microtubule-based movement+++GO:0008104///protein localization+++GO:0008285///negative regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0044782///cilium organization+++GO:0046587///positive regulation of calcium-dependent cell-cell adhesion 16580 16580 'Kifc5b' mRNA 15.21 17.05 4.63 0.32 0.35 0.1 0.36 0.32 0.27 0.256666667 0.316666667 19.39 16.89 14.48 12.29666667 16.92 0.609089948 0.451305038 GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0005815///microtubule organizing center+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030139///endocytic vesicle+++GO:0031616///spindle pole centrosome+++GO:0072686///mitotic spindle "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0007080///mitotic metaphase plate congression+++GO:0010826///negative regulation of centrosome duplication+++GO:0047496///vesicle transport along microtubule+++GO:0051301///cell division+++GO:0072382///minus-end-directed vesicle transport along microtubule+++GO:0090307///mitotic spindle assembly 16581 16581 'Kifc2' mRNA 767.24 776.73 757.45 12.77 12.53 13.06 5.33 5.1 5.07 12.78666667 5.166666667 366.33 346.35 348.06 767.14 353.58 3.33E-25 -1.129965238 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030139///endocytic vesicle+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0090307///mitotic spindle assembly 16582 16582 'Kifc3' mRNA 2034 1945 1831 32.49 29.98 30.94 19.29 18.63 17.52 31.13666667 18.48 1379 1294 1218 1936.666667 1297 9.18E-15 -0.589795925 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0042802///identical protein binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007017///microtubule-based process+++GO:0007018///microtubule-based movement+++GO:0007030///Golgi organization+++GO:0045218///zonula adherens maintenance+++GO:0090136///epithelial cell-cell adhesion 16588 16588 'Kin' mRNA 225 222 248 9.76 9.49 11.4 11.92 12.11 12.1 10.21666667 12.04333333 316 313 310 231.6666667 313 0.010493102 0.419665313 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus 16589 16589 'Uhmk1' mRNA 1271 1408 982 8.75 9.25 7.14 5.03 4.92 5.36 8.38 5.103333333 844 813 886 1220.333333 847.6666667 9.26E-07 -0.530882455 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030424///axon+++GO:0030496///midbody+++GO:0032839///dendrite cytoplasm+++GO:0071598///neuronal ribonucleoprotein granule GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1990935///splicing factor binding GO:0006468///protein phosphorylation+++GO:0007050///cell cycle arrest+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031175///neuron projection development+++GO:0045948///positive regulation of translational initiation+++GO:0046777///protein autophosphorylation+++GO:0046825///regulation of protein export from nucleus+++GO:0051726///regulation of cell cycle 16590 16590 'Kit' mRNA 1574 1607 1577 16.24 16.3 17.26 1.6 2.01 1.6 16.6 1.736666667 178 219 173 1586 190 1.83E-165 -3.07272552 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04640///Hematopoietic cell lineage+++04916///Melanogenesis+++05200///Pathways in cancer+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05230///Central carbon metabolism in cancer GO:0001650///fibrillar center+++GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005020///stem cell factor receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019955///cytokine binding+++GO:0042169///SH2 domain binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0000187///activation of MAPK activity+++GO:0001541///ovarian follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002318///myeloid progenitor cell differentiation+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0002327///immature B cell differentiation+++GO:0002551///mast cell chemotaxis+++GO:0002573///myeloid leukocyte differentiation+++GO:0002732///positive regulation of dendritic cell cytokine production+++GO:0006468///protein phosphorylation+++GO:0006687///glycosphingolipid metabolic process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008284///positive regulation of cell proliferation+++GO:0008354///germ cell migration+++GO:0008360///regulation of cell shape+++GO:0008542///visual learning+++GO:0008584///male gonad development+++GO:0009314///response to radiation+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030318///melanocyte differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031532///actin cytoskeleton reorganization+++GO:0032765///positive regulation of mast cell cytokine production+++GO:0033674///positive regulation of kinase activity+++GO:0035019///somatic stem cell population maintenance+++GO:0035162///embryonic hemopoiesis+++GO:0035234///ectopic germ cell programmed cell death+++GO:0035556///intracellular signal transduction+++GO:0035701///hematopoietic stem cell migration+++GO:0035855///megakaryocyte development+++GO:0038093///Fc receptor signaling pathway+++GO:0038109///Kit signaling pathway+++GO:0038162///erythropoietin-mediated signaling pathway+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043069///negative regulation of programmed cell death+++GO:0043303///mast cell degranulation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043473///pigmentation+++GO:0043586///tongue development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046686///response to cadmium ion+++GO:0046777///protein autophosphorylation+++GO:0048066///developmental pigmentation+++GO:0048103///somatic stem cell division+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0048565///digestive tract development+++GO:0048863///stem cell differentiation+++GO:0050673///epithelial cell proliferation+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060326///cell chemotaxis+++GO:0060374///mast cell differentiation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0097324///melanocyte migration+++GO:0097326///melanocyte adhesion+++GO:0120072///positive regulation of pyloric antrum smooth muscle contraction+++GO:1904251///regulation of bile acid metabolic process+++GO:1904343///positive regulation of colon smooth muscle contraction+++GO:1904349///positive regulation of small intestine smooth muscle contraction+++GO:1905065///positive regulation of vascular smooth muscle cell differentiation 16591 16591 'Kl' mRNA 154 190 148 1.64 1.99 1.67 1.2 1 1.06 1.766666667 1.086666667 133 108 113 164 118 0.031750091 -0.485150722 "00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++04211///Longevity regulating pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004566///beta-glucuronidase activity+++GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008422///beta-glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0017134///fibroblast growth factor binding" GO:0002526///acute inflammatory response+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0005975///carbohydrate metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0007568///aging+++GO:0008152///metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0030501///positive regulation of bone mineralization+++GO:0042421///norepinephrine biosynthetic process+++GO:0055074///calcium ion homeostasis+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 16592 16592 'Fabp5' mRNA 93 80 99 6.32 5.38 7.13 195.13 189.97 187.14 6.276666667 190.7466667 3292 3122 3048 90.66666667 3154 0 5.107829402 03320///PPAR signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse GO:0001972///retinoic acid binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0006006///glucose metabolic process+++GO:0006629///lipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0010829///negative regulation of glucose transmembrane transport+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0031392///regulation of prostaglandin biosynthetic process+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0042593///glucose homeostasis+++GO:0051930///regulation of sensory perception of pain+++GO:0099178///regulation of retrograde trans-synaptic signaling by endocanabinoid+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1990379///lipid transport across blood brain barrier 16593 16593 'Klc1' mRNA 2072.51 2098.33 2063.14 44.26 44.54 46.61 44.76 40.64 43.31 45.13666667 42.90333333 2407.11 2136.59 2218.71 2077.993333 2254.136667 0.198244657 0.104061226 05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0035253///ciliary rootlet+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043227///membrane-bounded organelle GO:0005515///protein binding+++GO:0015631///tubulin binding GO:0006886///intracellular protein transport+++GO:0007018///microtubule-based movement+++GO:0008088///axo-dendritic transport+++GO:0035418///protein localization to synapse+++GO:0035617///stress granule disassembly 16594 16594 'Klc2' mRNA 329 357 151 6.16 6.6 3.01 2.4 2.41 2.48 5.256666667 2.43 147 145 147 279 146.3333333 2.18E-04 -0.926215088 05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0035253///ciliary rootlet+++GO:0043005///neuron projection GO:0005515///protein binding+++GO:0019894///kinesin binding GO:0007018///microtubule-based movement+++GO:0008088///axo-dendritic transport+++GO:0032418///lysosome localization 16596 16596 'Klf1' mRNA 32 19 26 1.28 0.75 1.11 0.1 0.32 0.4 1.046666667 0.273333333 3 9 11 25.66666667 7.666666667 0.011178737 -1.751799246 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0033613///activating transcription factor binding+++GO:0046872///metal ion binding" "GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0030218///erythrocyte differentiation+++GO:0035162///embryonic hemopoiesis+++GO:0043249///erythrocyte maturation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048821///erythrocyte development+++GO:0060135///maternal process involved in female pregnancy+++GO:1901653///cellular response to peptide" 16597 16597 'Klf12' mRNA 3062 3236 2830 24.57 25.67 24.24 5.44 4.92 4.94 24.82666667 5.1 811 744 733 3042.666667 762.6666667 9.99E-172 -2.006766462 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 16598 16598 'Klf2' mRNA 147 131 36 4.66 4.09 1.21 3.64 3.65 3.79 3.32 3.693333333 132 129 133 104.6666667 131.3333333 0.42042963 0.33814926 04068///FoxO signaling pathway+++04371///Apelin signaling pathway+++05418///Fluid shear stress and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032715///negative regulation of interleukin-6 production+++GO:0034101///erythrocyte homeostasis+++GO:0034616///response to laminar fluid shear stress+++GO:0035264///multicellular organism growth+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042311///vasodilation+++GO:0043249///erythrocyte maturation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0051247///positive regulation of protein metabolic process+++GO:0060509///type I pneumocyte differentiation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0071409///cellular response to cycloheximide+++GO:0071498///cellular response to fluid shear stress+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0097533///cellular stress response to acid chemical+++GO:1901653///cellular response to peptide+++GO:1903671///negative regulation of sprouting angiogenesis" 16599 16599 'Klf3' mRNA 2384 2267 1371 25.04 23.42 15.29 11.05 10.6 12.44 21.25 11.36333333 1204 1132 1317 2007.333333 1217.666667 0.002193237 -0.721455321 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1901653///cellular response to peptide 16600 16600 'Klf4' mRNA 97 70 73 1.57 1.1 1.26 1.99 1.7 2.25 1.31 1.98 136 113 143 80 130.6666667 0.007947578 0.69622772 04550///Signaling pathways regulating pluripotency of stem cells+++05207///Chemical carcinogenesis - receptor activation GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001010///RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002357///defense response to tumor cell+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0009913///epidermal cell differentiation+++GO:0010033///response to organic substance+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0014740///negative regulation of muscle hyperplasia+++GO:0016525///negative regulation of angiogenesis+++GO:0019827///stem cell population maintenance+++GO:0030154///cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0031077///post-embryonic camera-type eye development+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032526///response to retinoic acid+++GO:0032717///negative regulation of interleukin-8 production+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0035166///post-embryonic hemopoiesis+++GO:0042127///regulation of cell proliferation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045444///fat cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048679///regulation of axon regeneration+++GO:0048730///epidermis morphogenesis+++GO:0051247///positive regulation of protein metabolic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0051973///positive regulation of telomerase activity+++GO:0060070///canonical Wnt signaling pathway+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071409///cellular response to cycloheximide+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1901653///cellular response to peptide+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904798///positive regulation of core promoter binding+++GO:1904998///negative regulation of leukocyte adhesion to arterial endothelial cell+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production" 16601 16601 'Klf9' mRNA 2020 2150 1123 24.2 25.33 14.27 15.38 16.76 17.78 21.26666667 16.64 1478 1573 1655 1764.333333 1568.666667 0.631237795 -0.166370527 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007566///embryo implantation+++GO:0007623///circadian rhythm+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050847///progesterone receptor signaling pathway+++GO:0071387///cellular response to cortisol stimulus+++GO:0097067///cellular response to thyroid hormone stimulus" 16612 16612 'Klk1' mRNA 1 0 0 0.07 0 0 0.06 0.36 0.06 0.023333333 0.16 1 6 1 0.333333333 2.666666667 0.261491881 2.898597855 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 16615 16615 'Klk1b16' mRNA 0 0 1 0 0 0.08 0 0 0.07 0.026666667 0.023333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 16616 16616 'Klk1b21' mRNA 2 2 0 0.14 0.14 0 0.38 0.26 0.2 0.093333333 0.28 6 4 3 1.333333333 4.333333333 0.337895893 1.707284305 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 16617 16617 'Klk1b24' mRNA 0 0 1 0 0 0.08 0 0.2 0.14 0.026666667 0.113333333 0 3 2 0.333333333 1.666666667 0.498653683 2.222470753 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0001669///acrosomal vesicle+++GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 16619 16619 'Klk1b27' mRNA 0 1 1 0 0.07 0.08 0.26 0.2 0.2 0.05 0.22 4 3 3 0.666666667 3.333333333 0.279317611 2.300626996 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0031638///zymogen activation 16621 16621 'Klkb1' mRNA 29 38 26 0.3 0.38 0.28 0 0.06 0 0.32 0.02 0 7 0 31 2.333333333 2.11E-05 -3.727322716 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0031639///plasminogen activation+++GO:0042730///fibrinolysis+++GO:0051919///positive regulation of fibrinolysis 16622 16622 'Klk1b5' mRNA 0 1 0 0 0.08 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0097209///epidermal lamellar body "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0002803///positive regulation of antibacterial peptide production+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0022617///extracellular matrix disassembly+++GO:0031638///zymogen activation+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0097186///amelogenesis 16624 16624 'Klk1b8' mRNA 0 1 0 0 0.08 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04614///Renin-angiotensin system+++04961///Endocrine and other factor-regulated calcium reabsorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0097180///serine protease inhibitor complex "GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0007613///memory+++GO:0008219///cell death+++GO:0009611///response to wounding+++GO:0031638///zymogen activation+++GO:0031642///negative regulation of myelination+++GO:0043616///keratinocyte proliferation+++GO:0048681///negative regulation of axon regeneration+++GO:0048812///neuron projection morphogenesis+++GO:0050807///regulation of synapse organization+++GO:0050808///synapse organization 16625 16625 'Serpina3c' mRNA 0 0.44 0.91 0 0.01 0.03 0.09 0.09 0.03 0.013333333 0.07 2.95 2.96 1 0.45 2.303333333 0.332755229 3.166742631 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 16633 16633 'Klra2' mRNA 37 32 27 1.19 1.02 0.99 5.51 4.57 5.38 1.066666667 5.153333333 196 158 181 32 178.3333333 8.78E-21 2.467894459 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0007155///cell adhesion 16635 16635 'Klra4' mRNA 0 1 0 0 0.07 0 0.21 0.25 0.18 0.023333333 0.213333333 4 5 4 0.333333333 4.333333333 0.082428538 3.5865234 04650///Natural killer cell mediated cytotoxicity+++05144///Malaria GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0007155///cell adhesion 16636 16636 'Klra5' mRNA 2 0 0 0.11 0 0 0.05 0.19 0.19 0.036666667 0.143333333 1 4 2 0.666666667 2.333333333 0.492246407 1.823282864 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0007155///cell adhesion 16638 16638 'Klra7' mRNA 0 1 0 0 0.06 0 0.61 0.63 0.63 0.02 0.623333333 12 12 12 0.333333333 12 0.001273711 5.054265717 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0007155///cell adhesion 16639 16639 'Klra8' mRNA 0 2 0 0 0.1 0 1.65 1.85 2.11 0.033333333 1.87 35.21 38.29 43.76 0.666666667 39.08666667 8.41E-07 5.853418967 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0007155///cell adhesion+++GO:0009615///response to virus 16640 16640 'Klra9' mRNA 1 0 2 0.05 0 0.08 1.59 2.54 1.85 0.043333333 1.993333333 36.13 58.06 40.83 1 45.00666667 3.94E-08 5.46870937 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0007155///cell adhesion 16641 16641 'Klrc1' mRNA 4 10 0 0.12 0.28 0 0.32 0.5 0.92 0.133333333 0.58 13 19.61 35.01 4.666666667 22.54 0.010366295 2.279219349 04612///Antigen processing and presentation+++04650///Natural killer cell mediated cytotoxicity+++05332///Graft-versus-host disease GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0023024///MHC class I protein complex binding+++GO:1990405///protein antigen binding "GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002228///natural killer cell mediated immunity+++GO:0002305///CD8-positive, gamma-delta intraepithelial T cell differentiation+++GO:0002769///natural killer cell inhibitory signaling pathway+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity" 16642 16642 'Klrc2' mRNA 0 0 2 0 0 0.14 0 0.13 0.27 0.046666667 0.133333333 0 1.39 2.99 0.666666667 1.46 0.886537466 0.525102185 GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0023024///MHC class I protein complex binding+++GO:1990405///protein antigen binding GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002228///natural killer cell mediated immunity+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 16643 16643 'Klrd1' mRNA 1 2 5 0.08 0.1 0.37 1.12 2.07 1.46 0.183333333 1.55 19 34 26 2.666666667 26.33333333 6.88E-05 3.284424756 04612///Antigen processing and presentation+++04650///Natural killer cell mediated cytotoxicity+++05332///Graft-versus-host disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex "GO:0004888///transmembrane signaling receptor activity+++GO:0023024///MHC class I protein complex binding+++GO:0023030///MHC class Ib protein binding, via antigen binding groove+++GO:0030246///carbohydrate binding+++GO:1990405///protein antigen binding" GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002228///natural killer cell mediated immunity+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 16644 16644 'Kng1' mRNA 2.03 0 0 0.06 0 0 5.4 4.13 4.97 0.02 4.833333333 193.72 156.97 187.15 0.676666667 179.28 7.55E-14 8.05461904 04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++05142///Chagas disease+++05143///African trypanosomiasis+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0030414///peptidase inhibitor activity GO:0006954///inflammatory response+++GO:0007162///negative regulation of cell adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030195///negative regulation of blood coagulation+++GO:0031640///killing of cells of other organism+++GO:0042311///vasodilation+++GO:0045861///negative regulation of proteolysis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 16646 16646 'Kpna1' mRNA 895 949 974 10.29 11.17 12.31 12.69 11.17 12.78 11.25666667 12.21333333 1226 1062 1176 939.3333333 1154.666667 0.004588085 0.283157051 03013///Nucleocytoplasmic transport+++05132///Salmonella infection+++05164///Influenza A+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0014841///skeletal muscle satellite cell proliferation+++GO:0014901///satellite cell activation involved in skeletal muscle regeneration+++GO:0015031///protein transport+++GO:0042981///regulation of apoptotic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0099527///postsynapse to nucleus signaling pathway 16647 16647 'Kpna2' mRNA 529 596 608.6 14.75 16.37 18 50.51 50.7 50.16 16.37333333 50.45666667 2082.87 2041 2002 577.8666667 2041.956667 6.79E-91 1.807858037 03013///Nucleocytoplasmic transport+++05164///Influenza A+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0043657///host cell+++GO:0098892///extrinsic component of postsynaptic specialization membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0042826///histone deacetylase binding+++GO:0061608///nuclear import signal receptor activity+++GO:0070491///repressing transcription factor binding GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0015031///protein transport+++GO:0046015///regulation of transcription by glucose+++GO:0075506///entry of viral genome into host nucleus through nuclear pore complex via importin+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1903902///positive regulation of viral life cycle 16648 16648 'Kpna3' mRNA 535 585 524 6.92 7.44 7.19 11.46 9.86 10.64 7.183333333 10.65333333 1020 858 918 548 932 1.41E-13 0.754028534 03013///Nucleocytoplasmic transport+++05132///Salmonella infection+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0008022///protein C-terminus binding+++GO:0008139///nuclear localization sequence binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0015031///protein transport 16649 16649 'Kpna4' mRNA 374 389 347 5.44 5.56 5.35 7.25 6.99 6.9 5.45 7.046666667 574 540 529 370 547.6666667 3.43E-06 0.554976418 03013///Nucleocytoplasmic transport+++05132///Salmonella infection+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0015031///protein transport+++GO:0042542///response to hydrogen peroxide 16650 16650 'Kpna6' mRNA 878 908 604 8.17 8.31 5.96 6.74 5.12 6.22 7.48 6.026666667 834 619 745 796.6666667 732.6666667 0.43920397 -0.126910576 03013///Nucleocytoplasmic transport+++05164///Influenza A+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043657///host cell GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0015031///protein transport+++GO:0019079///viral genome replication+++GO:0030682///evasion or tolerance of host defense response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060135///maternal process involved in female pregnancy+++GO:0075506///entry of viral genome into host nucleus through nuclear pore complex via importin+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1903902///positive regulation of viral life cycle 16651 16651 'Sspn' mRNA 366 318 345.07 4.37 3.72 4.31 4.64 4.29 4.76 4.133333333 4.563333333 446.01 402.02 442.01 343.0233333 430.0133333 0.029446878 0.312584688 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0042383///sarcolemma+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane 16653 16653 'Kras' mRNA 668.26 681.83 507.26 7.65 7.68 6.16 6.24 5.86 6.75 7.163333333 6.283333333 627.61 576.43 657.64 619.1166667 620.56 0.988951037 -0.003587216 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04214///Apoptosis - fly+++04218///Cellular senescence+++04320///Dorso-ventral axis formation+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019002///GMP binding+++GO:0019003///GDP binding+++GO:0030275///LRR domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding "GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0021897///forebrain astrocyte development+++GO:0030036///actin cytoskeleton organization+++GO:0031647///regulation of protein stability+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0035900///response to isolation stress+++GO:0038002///endocrine signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051146///striated muscle cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0051385///response to mineralocorticoid+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:2000774///positive regulation of cellular senescence" 16656 16656 'Hivep3' mRNA 189 226 149 1.18 1.35 0.95 2.61 2.78 2.78 1.16 2.723333333 493 499 490 188 494 1.99E-20 1.388160119 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035914///skeletal muscle cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated" 16658 16658 'Mafb' mRNA 133 137 117 2.14 2.17 2 23.61 20.93 21.73 2.103333333 22.09 1690 1463 1506 129 1553 1.15E-211 3.578408942 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007379///segment specification+++GO:0007585///respiratory gaseous exchange+++GO:0021571///rhombomere 5 development+++GO:0021572///rhombomere 6 development+++GO:0021599///abducens nerve formation+++GO:0033077///T cell differentiation in thymus+++GO:0035284///brain segmentation+++GO:0042472///inner ear morphogenesis+++GO:0045637///regulation of myeloid cell differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048538///thymus development" 16661 16661 'Krt10' mRNA 252.05 243 278 5.93 5.61 7.14 3.71 3.24 3.22 6.226666667 3.39 181.07 153.53 142.09 257.6833333 158.8966667 1.30E-04 -0.716235676 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0009986///cell surface+++GO:0045095///keratin filament GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0030280///structural constituent of epidermis+++GO:0046982///protein heterodimerization activity GO:0003334///keratinocyte development+++GO:0008544///epidermis development+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0030855///epithelial cell differentiation+++GO:0045109///intermediate filament organization+++GO:0045684///positive regulation of epidermis development+++GO:0051290///protein heterotetramerization+++GO:0071277///cellular response to calcium ion 16667 16667 'Krt17' mRNA 1 3 2 0.04 0.15 0.1 2.67 2.5 2.79 0.096666667 2.653333333 81 74 82 2 79 3.56E-14 5.292893486 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0045111///intermediate filament cytoskeleton+++GO:0071944///cell periphery GO:0005198///structural molecule activity+++GO:0005515///protein binding GO:0002009///morphogenesis of an epithelium+++GO:0030307///positive regulation of cell growth+++GO:0031069///hair follicle morphogenesis+++GO:0031424///keratinization+++GO:0045109///intermediate filament organization+++GO:0045727///positive regulation of translation+++GO:0051798///positive regulation of hair follicle development 16668 16668 'Krt18' mRNA 4264 4471 4467 181.94 188.24 202.22 553.7 594.27 563.24 190.8 570.4033333 14902 15604 14663 4400.666667 15056.33333 1.29E-182 1.762028139 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0045095///keratin filament+++GO:0071944///cell periphery GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0097110///scaffold protein binding GO:0009750///response to fructose+++GO:0031667///response to nutrient levels+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0043066///negative regulation of apoptotic process+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0070365///hepatocyte differentiation+++GO:0072497///mesenchymal stem cell differentiation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:1902488///cholangiocyte apoptotic process 16669 16669 'Krt19' mRNA 189 169 150 8.47 7.46 7.08 14.82 13.88 14.04 7.67 14.24666667 393 359 360 169.3333333 370.6666667 4.32E-13 1.120233418 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016327///apicolateral plasma membrane+++GO:0030018///Z disc+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0071944///cell periphery+++GO:1990357///terminal web GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0044877///protein-containing complex binding GO:0007219///Notch signaling pathway+++GO:0043627///response to estrogen+++GO:0045214///sarcomere organization+++GO:0060706///cell differentiation involved in embryonic placenta development 16670 16670 'Krt32' mRNA 1 0 1 0.03 0 0.04 0 0.03 0 0.023333333 0.01 0 1 0 0.666666667 0.333333333 0.859375267 -0.929010473 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament GO:0005198///structural molecule activity 16678 16678 'Krt1' mRNA 9 5 2 0.21 0.11 0.05 0.06 0.16 0.1 0.123333333 0.106666667 3 8 5 5.333333333 5.333333333 0.998591786 0.011966081 GO:0001533///cornified envelope+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045095///keratin filament+++GO:0062023///collagen-containing extracellular matrix GO:0030246///carbohydrate binding+++GO:0030280///structural constituent of epidermis+++GO:0046982///protein heterodimerization activity "GO:0001867///complement activation, lectin pathway+++GO:0018149///peptide cross-linking+++GO:0050728///negative regulation of inflammatory response+++GO:0051290///protein heterotetramerization+++GO:0061436///establishment of skin barrier" 16679 16679 'Krt86' mRNA 0 2 1 0 0.06 0.03 0 0 0 0.03 0 0 0 0 1 0 0.607488248 -2.448949589 GO:0005882///intermediate filament+++GO:0045095///keratin filament 16680 16680 'Krt84' mRNA 4 0 0 0.09 0 0 0.04 0 0 0.03 0.013333333 2 0 0 1.333333333 0.666666667 0.806888479 -1.012492175 GO:0005882///intermediate filament+++GO:0045095///keratin filament+++GO:0045111///intermediate filament cytoskeleton GO:0030280///structural constituent of epidermis GO:0045616///regulation of keratinocyte differentiation 16691 16691 'Krt8' mRNA 2330 2619 2492 74.37 82.39 84.39 371.4 405.65 371.12 80.38333333 382.7233333 13373 14257 12932 2480.333333 13520.66667 4.21E-289 2.434834346 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0005911///cell-cell junction+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016327///apicolateral plasma membrane+++GO:0016363///nuclear matrix+++GO:0030018///Z disc+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0045095///keratin filament+++GO:0045111///intermediate filament cytoskeleton+++GO:0071944///cell periphery GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding GO:0000904///cell morphogenesis involved in differentiation+++GO:0007275///multicellular organism development+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045214///sarcomere organization+++GO:0051599///response to hydrostatic pressure+++GO:0051707///response to other organism+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097284///hepatocyte apoptotic process 16706 16706 'Ksr1' mRNA 561.74 616 499 4.47 4.9 4.24 2.82 2.88 2.98 4.536666667 2.893333333 415.26 408 426.38 558.9133333 416.5466667 3.65E-04 -0.43286009 04014///Ras signaling pathway+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0071889///14-3-3 protein binding GO:0000185///activation of MAPKKK activity+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0016310///phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0043405///regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade 16709 16709 'Ktn1' mRNA 1694 1760 1814 20.27 20.7 22.9 16.62 16.32 16.56 21.29 16.5 1601 1537 1537 1756 1558.333333 0.03094218 -0.186189343 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0019894///kinesin binding GO:0007018///microtubule-based movement+++GO:0015031///protein transport 16716 16716 'Ky' mRNA 0 0 1 0 0 0.04 0 0.03 0 0.013333333 0.01 0 2 0 0.333333333 0.666666667 0.863090843 0.906589207 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030018///Z disc GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007517///muscle organ development+++GO:0007528///neuromuscular junction development 16728 16728 'L1cam' mRNA 306 373 327 3.13 3.75 3.54 2.05 1.52 1.17 3.473333333 1.58 231 167 128 335.3333333 175.3333333 1.89E-06 -0.950240055 04360///Axon guidance+++04514///Cell adhesion molecules GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0045121///membrane raft+++GO:0098685///Schaffer collateral - CA1 synapse GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008046///axon guidance receptor activity+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0033691///sialic acid binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0016477///cell migration+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034109///homotypic cell-cell adhesion+++GO:0045773///positive regulation of axon extension+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0061564///axon development+++GO:0070372///regulation of ERK1 and ERK2 cascade 16763 16763 'Lad1' mRNA 322 385 237 5.91 6.96 4.62 3.97 4.38 4.17 5.83 4.173333333 249 268 253 314.6666667 256.6666667 0.118435479 -0.296702391 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0015629///actin cytoskeleton GO:0005198///structural molecule activity 16764 16764 'Aff3' mRNA 330 324 329 2.81 2.69 2.98 1.75 1.71 1.79 2.826666667 1.75 233 229 235 327.6666667 232.3333333 9.18E-04 -0.508615614 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032783///ELL-EAF complex GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010468///regulation of gene expression+++GO:0034612///response to tumor necrosis factor+++GO:0035116///embryonic hindlimb morphogenesis" 16765 16765 'Stmn1' mRNA 4307 4112 4316 256.21 241.79 272.42 248.35 262.94 247.81 256.8066667 253.0333333 4788 4942 4618 4245 4782.666667 0.030097082 0.158907904 04010///MAPK signaling pathway+++05206///MicroRNAs in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0043005///neuron projection GO:0005515///protein binding+++GO:0015631///tubulin binding GO:0000281///mitotic cytokinesis+++GO:0007019///microtubule depolymerization+++GO:0007052///mitotic spindle organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0009615///response to virus+++GO:0030154///cell differentiation+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031175///neuron projection development+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0051272///positive regulation of cellular component movement+++GO:0051497///negative regulation of stress fiber assembly+++GO:0061436///establishment of skin barrier+++GO:0070495///negative regulation of thrombin-activated receptor signaling pathway+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity 16768 16768 'Lag3' mRNA 311 271 280 8.84 7.59 8.44 6.77 6.18 6 8.29 6.316666667 274 244 235 287.3333333 251 0.244766276 -0.20800778 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042289///MHC class II protein binding GO:0002250///adaptive immune response+++GO:0002270///plasmacytoid dendritic cell activation+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0032703///negative regulation of interleukin-2 production+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050776///regulation of immune response+++GO:0050868///negative regulation of T cell activation 16770 16770 'Lalba' mRNA 0 1 0 0 0.1 0 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00052///Galactose metabolism GO:0005576///extracellular region GO:0004461///lactose synthase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0005989///lactose biosynthetic process 16772 16772 'Lama1' mRNA 350 342 327 1.96 1.84 1.9 3.01 3.04 3.06 1.9 3.036666667 616 617 620 339.6666667 617.6666667 2.15E-13 0.851670421 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005606///laminin-1 complex+++GO:0005608///laminin-3 complex+++GO:0005615///extracellular space+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0043256///laminin complex+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0043208///glycosphingolipid binding GO:0002011///morphogenesis of an epithelial sheet+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007411///axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0031175///neuron projection development+++GO:0043010///camera-type eye development+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045995///regulation of embryonic development+++GO:0048514///blood vessel morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0061304///retinal blood vessel morphogenesis 16773 16773 'Lama2' mRNA 2070 2062 1893 11.26 11.02 10.93 7.02 7.25 7.76 11.07 7.343333333 1486 1489 1585 2008.333333 1520 1.96E-08 -0.412208767 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016020///membrane+++GO:0031594///neuromuscular junction+++GO:0042383///sarcolemma+++GO:0043083///synaptic cleft+++GO:0043197///dendritic spine+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent "GO:0007155///cell adhesion+++GO:0007411///axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0014037///Schwann cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0045995///regulation of embryonic development" 16774 16774 'Lama3' mRNA 17 11 11 0.12 0.08 0.07 0.15 0.16 0.23 0.09 0.18 31 23 43 13 32.33333333 0.02233987 1.304475872 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005608///laminin-3 complex+++GO:0005610///laminin-5 complex+++GO:0005783///endoplasmic reticulum+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030056///hemidesmosome+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent GO:0001738///morphogenesis of a polarized epithelium+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007411///axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0031581///hemidesmosome assembly+++GO:0035987///endodermal cell differentiation+++GO:0045995///regulation of embryonic development+++GO:0098609///cell-cell adhesion 16775 16775 'Lama4' mRNA 598 507 494 5.25 4.37 4.6 11.03 10.29 10.74 4.74 10.68666667 1447 1320 1365 533 1377.333333 3.86E-46 1.358433954 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05143///African trypanosomiasis+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016020///membrane+++GO:0031594///neuromuscular junction+++GO:0043083///synaptic cleft+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent GO:0001568///blood vessel development+++GO:0007155///cell adhesion+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0045995///regulation of embryonic development+++GO:0050873///brown fat cell differentiation+++GO:0120163///negative regulation of cold-induced thermogenesis 16776 16776 'Lama5' mRNA 1869 1807 1734 8.53 8.1 8.39 7.04 6.11 6.6 8.34 6.583333333 1776 1512 1617 1803.333333 1635 0.066101905 -0.153990317 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005610///laminin-5 complex+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0043083///synaptic cleft+++GO:0043259///laminin-10 complex+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0001755///neural crest cell migration+++GO:0001822///kidney development+++GO:0001942///hair follicle development+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007411///axon guidance+++GO:0007517///muscle organ development+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0016477///cell migration+++GO:0030155///regulation of cell adhesion+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045995///regulation of embryonic development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0060271///cilium assembly+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0098609///cell-cell adhesion 16777 16777 'Lamb1' mRNA 716 774 779 6.58 6.99 7.61 10.36 9.97 9.86 7.06 10.06333333 1295 1216 1197 756.3333333 1236 7.05E-14 0.694936647 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005606///laminin-1 complex+++GO:0005607///laminin-2 complex+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0043256///laminin complex+++GO:0043257///laminin-8 complex+++GO:0043259///laminin-10 complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0043208///glycosphingolipid binding GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0007566///embryo implantation+++GO:0007611///learning or memory+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0021812///neuronal-glial interaction involved in cerebral cortex radial glia guided migration+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042476///odontogenesis+++GO:0070831///basement membrane assembly 16779 16779 'Lamb2' mRNA 4329 4423 4546 40.93 41.11 45.59 36.5 34.89 34.62 42.54333333 35.33666667 4445 4152 4083 4432.666667 4226.666667 0.288472002 -0.08287011 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005608///laminin-3 complex+++GO:0016020///membrane+++GO:0031594///neuromuscular junction+++GO:0043083///synaptic cleft+++GO:0043256///laminin complex+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent GO:0000904///cell morphogenesis involved in differentiation+++GO:0007155///cell adhesion+++GO:0007411///axon guidance+++GO:0007528///neuromuscular junction development+++GO:0007601///visual perception+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0014002///astrocyte development+++GO:0014044///Schwann cell development+++GO:0016477///cell migration+++GO:0031175///neuron projection development+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0048677///axon extension involved in regeneration+++GO:0050808///synapse organization+++GO:0060041///retina development in camera-type eye+++GO:0070831///basement membrane assembly+++GO:0072249///metanephric glomerular visceral epithelial cell development+++GO:0072274///metanephric glomerular basement membrane development 16780 16780 'Lamb3' mRNA 145 156 118 1.95 2.07 1.67 4.38 4.17 4.3 1.896666667 4.283333333 377 349 357 139.6666667 361 2.67E-17 1.361634109 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005610///laminin-5 complex+++GO:0043256///laminin complex+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0044877///protein-containing complex binding GO:0007155///cell adhesion+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035987///endodermal cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0070831///basement membrane assembly 16782 16782 'Lamc2' mRNA 918 888 915 9.6 9.16 10.15 15.15 13.69 14.38 9.636666667 14.40666667 1668 1463 1528 907 1553 5.39E-19 0.762026267 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005607///laminin-2 complex+++GO:0005610///laminin-5 complex+++GO:0005615///extracellular space+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0007155///cell adhesion+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016358///dendrite development+++GO:0030335///positive regulation of cell migration 16783 16783 'Lamp1' mRNA 17035 17654 8409 430.26 439.13 225.3 396.66 616.03 554.97 364.8966667 522.5533333 18060 27385 24459 14366 23301.33333 0.055453125 0.706589171 04140///Autophagy - animal+++04142///Lysosome+++04145///Phagosome+++05152///Tuberculosis GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005773///vacuole+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0044194///cytolytic granule+++GO:0044754///autolysosome+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0061474///phagolysosome membrane+++GO:0097208///alveolar lamellar body+++GO:0101004///cytolytic granule membrane GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding GO:0007283///spermatogenesis+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0048102///autophagic cell death+++GO:0050821///protein stabilization+++GO:0072594///establishment of protein localization to organelle+++GO:0090160///Golgi to lysosome transport+++GO:1902513///regulation of organelle transport along microtubule 16784 16784 'Lamp2' mRNA 6436 6650 6660 140.26 141.63 151.36 235.48 230.78 230.75 144.4166667 232.3366667 12643 12087 11784 6582 12171.33333 6.28E-53 0.873427393 04140///Autophagy - animal+++04142///Lysosome+++04145///Phagosome+++05152///Tuberculosis GO:0000421///autophagosome membrane+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031088///platelet dense granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0044754///autolysosome+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0061742///chaperone-mediated autophagy translocation complex+++GO:0070062///extracellular exosome+++GO:0097637///integral component of autophagosome membrane+++GO:1990836///lysosomal matrix GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding GO:0006605///protein targeting+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0031333///negative regulation of protein complex assembly+++GO:0031647///regulation of protein stability+++GO:0046716///muscle cell cellular homeostasis+++GO:0050821///protein stabilization+++GO:0061684///chaperone-mediated autophagy+++GO:0061740///protein targeting to lysosome involved in chaperone-mediated autophagy+++GO:0072594///establishment of protein localization to organelle+++GO:0097352///autophagosome maturation+++GO:1905146///lysosomal protein catabolic process 16785 16785 'Rpsa' mRNA 4199 4256 3774 129.52 129.37 123.5 216.29 187.85 217.31 127.4633333 207.15 8060 6833 7837 4076.333333 7576.666667 2.79E-45 0.883153904 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0098978///glutamatergic synapse GO:0003735///structural constituent of ribosome+++GO:0005055///laminin receptor activity+++GO:0043022///ribosome binding+++GO:0043236///laminin binding GO:0000028///ribosomal small subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0007155///cell adhesion+++GO:0030855///epithelial cell differentiation+++GO:0098609///cell-cell adhesion 16790 16790 'Anpep' mRNA 507 542 364 7.23 7.63 5.5 17.04 16.07 16.21 6.786666667 16.44 1374 1267 1265 471 1302 1.66E-39 1.461256624 00480///Glutathione metabolism+++04614///Renin-angiotensin system+++04640///Hematopoietic cell lineage GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0070062///extracellular exosome GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0001525///angiogenesis+++GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0008217///regulation of blood pressure+++GO:0030154///cell differentiation+++GO:0035814///negative regulation of renal sodium excretion+++GO:0043171///peptide catabolic process 16792 16792 'Laptm5' mRNA 909 883 854 21.02 20.11 20.95 260.85 258.82 258.45 20.69333333 259.3733333 12971 12567 12442 882 12660 0 3.831916832 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0140036///ubiquitin-dependent protein binding GO:0002357///defense response to tumor cell+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0006622///protein targeting to lysosome+++GO:0006886///intracellular protein transport+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0012502///induction of programmed cell death+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0043410///positive regulation of MAPK cascade+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050868///negative regulation of T cell activation+++GO:0050869///negative regulation of B cell activation+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061462///protein localization to lysosome+++GO:0090160///Golgi to lysosome transport+++GO:0097214///positive regulation of lysosomal membrane permeability+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1904093///negative regulation of autophagic cell death+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000646///positive regulation of receptor catabolic process 16795 16795 'Large1' mRNA 119 177 146 1.6 2.34 2.22 2.16 1.87 1.87 2.053333333 1.966666667 177 160 156 147.3333333 164.3333333 0.593032778 0.145688795 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0042285///xylosyltransferase activity+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008152///metabolic process+++GO:0009101///glycoprotein biosynthetic process+++GO:0035269///protein O-linked mannosylation+++GO:0043403///skeletal muscle tissue regeneration+++GO:0046716///muscle cell cellular homeostasis+++GO:0060538///skeletal muscle organ development 16796 16796 'Lasp1' mRNA 2590 2512 2540 40.26 38.26 41.52 71.25 67.59 67.02 40.01333333 68.62 5330 4951 4867 2547.333333 5049.333333 1.00E-54 0.973878413 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030864///cortical actin cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0015075///ion transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 16797 16797 'Lat' mRNA 21 12 18 1.01 0.57 0.9 1.26 1.24 1.23 0.826666667 1.243333333 31 28 29 17 29.33333333 0.175948706 0.771194872 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04064///NF-kappa B signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05135///Yersinia infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0001772///immunological synapse+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0008180///COP9 signalosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030159///receptor signaling complex scaffold activity GO:0002250///adaptive immune response+++GO:0002260///lymphocyte homeostasis+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0010467///gene expression+++GO:0019722///calcium-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0043303///mast cell degranulation+++GO:0045860///positive regulation of protein kinase activity+++GO:0048872///homeostasis of number of cells+++GO:0050863///regulation of T cell activation 16798 16798 'Lats1' mRNA 658 691 622 4.81 4.97 4.82 4.18 3.52 3.91 4.866666667 3.87 659 541 596 657 598.6666667 0.241009082 -0.146171398 04214///Apoptosis - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030331///estrogen receptor binding+++GO:0046872///metal ion binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0000819///sister chromatid segregation+++GO:0001827///inner cell mass cell fate commitment+++GO:0001828///inner cell mass cellular morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0009755///hormone-mediated signaling pathway+++GO:0016310///phosphorylation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030216///keratinocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034613///cellular protein localization+++GO:0035329///hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043254///regulation of protein complex assembly+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0046620///regulation of organ growth+++GO:0051220///cytoplasmic sequestering of protein+++GO:0051301///cell division+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900181///negative regulation of protein localization to nucleus+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process 16800 16800 'Arhgef2' mRNA 2906.63 3155.71 2658 28.43 30.93 27.57 26.7 28.08 27.27 28.97666667 27.35 3211.04 3277.24 3167 2906.78 3218.426667 0.050064097 0.138141757 04530///Tight junction+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05418///Fluid shear stress and atherosclerosis "GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0000132///establishment of mitotic spindle orientation+++GO:0000902///cell morphogenesis+++GO:0002376///immune system process+++GO:0007015///actin filament organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0045087///innate immune response+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050768///negative regulation of neurogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051301///cell division+++GO:0055059///asymmetric neuroblast division+++GO:0071225///cellular response to muramyl dipeptide+++GO:0071802///negative regulation of podosome assembly+++GO:2001224///positive regulation of neuron migration 16801 16801 'Arhgef1' mRNA 2066 2121 1570 34.24 34.48 27.72 28.8 37.28 34.98 32.14666667 33.68666667 2001 2552 2364 1919 2305.666667 0.020564904 0.261714977 "04270///Vascular smooth muscle contraction+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04928///Parathyroid hormone synthesis, secretion and action+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060548///negative regulation of cell death 16803 16803 'Lbp' mRNA 460 488 489 10.14 10.59 11.44 67.51 63.01 71.31 10.72333333 67.27666667 3522 3210 3602 479 3444.666667 5.81E-267 2.833326362 04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04936///Alcoholic liver disease+++05152///Tuberculosis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0016020///membrane GO:0001530///lipopolysaccharide binding+++GO:0005102///signaling receptor binding+++GO:0008289///lipid binding+++GO:0070891///lipoteichoic acid binding+++GO:0071723///lipopeptide binding "GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0006869///lipid transport+++GO:0006953///acute-phase response+++GO:0008228///opsonization+++GO:0015920///lipopolysaccharide transport+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032490///detection of molecule of bacterial origin+++GO:0032496///response to lipopolysaccharide+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033036///macromolecule localization+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0043032///positive regulation of macrophage activation+++GO:0045087///innate immune response+++GO:0045919///positive regulation of cytolysis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0060265///positive regulation of respiratory burst involved in inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090559///regulation of membrane permeability" 16814 16814 'Lbx1' mRNA 1 1 0 0.02 0.02 0 0.08 0 0.02 0.013333333 0.033333333 4 0 1 0.666666667 1.666666667 0.682670104 1.314861592 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001947///heart looping+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007517///muscle organ development+++GO:0008285///negative regulation of cell proliferation+++GO:0021522///spinal cord motor neuron differentiation+++GO:0030154///cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0048663///neuron fate commitment+++GO:0048664///neuron fate determination" 16815 16815 'Lbx2' mRNA 5 9 8 0.41 0.74 0.7 0.5 0.67 0.15 0.616666667 0.44 7 9 2 7.333333333 6 0.826718353 -0.302465273 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042692///muscle cell differentiation+++GO:1904105///positive regulation of convergent extension involved in gastrulation+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway 16816 16816 'Lcat' mRNA 505 441 428 22.25 19.18 20.01 21.14 20.3 20.91 20.48 20.78333333 551 516 527 458 531.3333333 0.121612251 0.203140188 00564///Glycerophospholipid metabolism+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034364///high-density lipoprotein particle "GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0004607///phosphatidylcholine-sterol O-acyltransferase activity+++GO:0004623///phospholipase A2 activity+++GO:0004806///triglyceride lipase activity+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0034186///apolipoprotein A-I binding+++GO:0047179///platelet-activating factor acetyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0030301///cholesterol transport+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034435///cholesterol esterification+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046688///response to copper ion+++GO:0051384///response to glucocorticoid+++GO:0090107///regulation of high-density lipoprotein particle assembly 16818 16818 'Lck' mRNA 66 72 78 1.87 2.01 2.34 3.3 3.89 3.67 2.073333333 3.62 136 158 148 72 147.3333333 3.11E-05 1.020186971 04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05135///Yersinia infection+++05166///Human T-cell leukemia virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency "GO:0000242///pericentriolar material+++GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0045121///membrane raft+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component" GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0003823///antigen binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0042169///SH2 domain binding+++GO:0042608///T cell receptor binding+++GO:0042609///CD4 receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding+++GO:0051117///ATPase binding+++GO:1990405///protein antigen binding GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006882///cellular zinc ion homeostasis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0010038///response to metal ion+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030217///T cell differentiation+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042542///response to hydrogen peroxide+++GO:0045087///innate immune response+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0046777///protein autophosphorylation+++GO:0050853///B cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:1903039///positive regulation of leukocyte cell-cell adhesion+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 16819 16819 'Lcn2' mRNA 973 957 1026 76.15 74.19 85.22 1455.67 1256.86 1432.67 78.52 1381.733333 21299 17913 20245 985.3333333 19819 0 4.315069556 04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0060205///cytoplasmic vesicle lumen GO:0002020///protease binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0036094///small molecule binding+++GO:0042802///identical protein binding+++GO:1903981///enterobactin binding GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006915///apoptotic process+++GO:0007614///short-term memory+++GO:0007616///long-term memory+++GO:0009410///response to xenobiotic stimulus+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0009635///response to herbicide+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0015891///siderophore transport+++GO:0031346///positive regulation of cell projection organization+++GO:0042493///response to drug+++GO:0042742///defense response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0055072///iron ion homeostasis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097577///sequestering of iron ion+++GO:0110091///negative regulation of hippocampal neuron apoptotic process+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901216///positive regulation of neuron death+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904440///positive regulation of ferrous iron import across plasma membrane+++GO:1905956///positive regulation of endothelial tube morphogenesis+++GO:2000379///positive regulation of reactive oxygen species metabolic process 16822 16822 'Lcp2' mRNA 83 59 94 1.24 0.87 1.49 12.68 14.16 12.91 1.2 13.25 974 1062 960 78.66666667 998.6666667 1.60E-121 3.651372936 04015///Rap1 signaling pathway+++04380///Osteoclast differentiation+++04611///Platelet activation+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0036398///TCR signalosome+++GO:0044853///plasma membrane raft GO:0005515///protein binding GO:0001816///cytokine production+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0045576///mast cell activation+++GO:0045860///positive regulation of protein kinase activity+++GO:0050852///T cell receptor signaling pathway 16825 16825 'Ldb1' mRNA 705 667 648 17.25 16.67 18.14 19.29 21.55 20.57 17.35333333 20.47 800 872 841 673.3333333 837.6666667 0.003922253 0.304572126 05202///Transcriptional misregulation in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:1990907///beta-catenin-TCF complex GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030274///LIM domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000972///transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0001702///gastrulation with mouth forming second+++GO:0001942///hair follicle development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009948///anterior/posterior axis specification+++GO:0010669///epithelial structure maintenance+++GO:0016055///Wnt signaling pathway+++GO:0021549///cerebellum development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0022607///cellular component assembly+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030334///regulation of cell migration+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0035019///somatic stem cell population maintenance+++GO:0043549///regulation of kinase activity+++GO:0043973///histone H3-K4 acetylation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0048382///mesendoderm development+++GO:0051893///regulation of focal adhesion assembly+++GO:0060319///primitive erythrocyte differentiation+++GO:0060322///head development" 16826 16826 'Ldb2' mRNA 290 239 256 6.53 5.51 6.03 5.63 5.87 5.99 6.023333333 5.83 292 305 301 261.6666667 299.3333333 0.31519719 0.182297844 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0030018///Z disc+++GO:0031143///pseudopodium+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003712///transcription coregulator activity+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0030274///LIM domain binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001942///hair follicle development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0010669///epithelial structure maintenance+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0035019///somatic stem cell population maintenance+++GO:0043549///regulation of kinase activity+++GO:0044089///positive regulation of cellular component biogenesis+++GO:0045214///sarcomere organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061061///muscle structure development 16828 16828 'Ldha' mRNA 11211 11866 11155 403.21 420.62 425.5 954.4 973.83 934.69 416.4433333 954.3066667 30482 30355 28898 11410.66667 29911.66667 1.64E-166 1.378643181 00010///Glycolysis / Gluconeogenesis+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035686///sperm fibrous sheath "GO:0003824///catalytic activity+++GO:0004457///lactate dehydrogenase activity+++GO:0004459///L-lactate dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0051287///NAD binding" GO:0001666///response to hypoxia+++GO:0005975///carbohydrate metabolic process+++GO:0006089///lactate metabolic process+++GO:0007584///response to nutrient+++GO:0009749///response to glucose+++GO:0014070///response to organic cyclic compound+++GO:0019244///lactate biosynthetic process from pyruvate+++GO:0019661///glucose catabolic process to lactate via pyruvate+++GO:0019674///NAD metabolic process+++GO:0019752///carboxylic acid metabolic process+++GO:0031668///cellular response to extracellular stimulus+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043627///response to estrogen+++GO:0048569///post-embryonic animal organ development+++GO:0051591///response to cAMP 16832 16832 'Ldhb' mRNA 30292 32272 30774 1405.45 1478 1514.98 926.21 978.16 945.76 1466.143333 950.0433333 22919 23615 22633 31112.66667 23055.66667 1.42E-16 -0.444145208 00010///Glycolysis / Gluconeogenesis+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045121///membrane raft "GO:0003824///catalytic activity+++GO:0004457///lactate dehydrogenase activity+++GO:0004459///L-lactate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0051287///NAD binding" GO:0005975///carbohydrate metabolic process+++GO:0006089///lactate metabolic process+++GO:0019244///lactate biosynthetic process from pyruvate+++GO:0019674///NAD metabolic process+++GO:0019752///carboxylic acid metabolic process 16833 16833 'Ldhc' mRNA 14 18 13 0.65 0.87 0.67 0.23 0 0.05 0.73 0.093333333 5 0 1 15 2 0.006197746 -2.926393065 00010///Glycolysis / Gluconeogenesis+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00640///Propanoate metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium "GO:0003824///catalytic activity+++GO:0004459///L-lactate dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006090///pyruvate metabolic process+++GO:0006754///ATP biosynthetic process+++GO:0019244///lactate biosynthetic process from pyruvate+++GO:0019516///lactate oxidation+++GO:0019752///carboxylic acid metabolic process+++GO:0030317///flagellated sperm motility 16834 16834 'Cog1' mRNA 1384.1 1486.87 1453.26 23.73 25.09 26.25 20.67 19.35 18.95 25.02333333 19.65666667 1370.11 1251.92 1216.98 1441.41 1279.67 0.041119971 -0.185495436 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport 16835 16835 'Ldlr' mRNA 1327 1426 1408 15.7 16.6 17.67 12.25 11.67 11.98 16.65666667 11.96666667 1192 1109 1129 1387 1143.333333 8.60E-04 -0.292088127 04144///Endocytosis+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++04976///Bile secretion+++04979///Cholesterol metabolism+++05145///Toxoplasmosis+++05160///Hepatitis C+++05417///Lipid and atherosclerosis GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0034362///low-density lipoprotein particle+++GO:0036477///somatodendritic compartment+++GO:0043235///receptor complex+++GO:0045177///apical part of cell+++GO:0055038///recycling endosome membrane+++GO:0097443///sorting endosome+++GO:1990666///PCSK9-LDLR complex GO:0001540///amyloid-beta binding+++GO:0002020///protease binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0030229///very-low-density lipoprotein particle receptor activity+++GO:0042802///identical protein binding+++GO:0071813///lipoprotein particle binding GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006909///phagocytosis+++GO:0007616///long-term memory+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0010899///regulation of phosphatidylcholine catabolic process+++GO:0015914///phospholipid transport+++GO:0030299///intestinal cholesterol absorption+++GO:0030301///cholesterol transport+++GO:0034381///plasma lipoprotein particle clearance+++GO:0034383///low-density lipoprotein particle clearance+++GO:0034384///high-density lipoprotein particle clearance+++GO:0042157///lipoprotein metabolic process+++GO:0042159///lipoprotein catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0048844///artery morphogenesis+++GO:0050729///positive regulation of inflammatory response+++GO:0051246///regulation of protein metabolic process+++GO:0051248///negative regulation of protein metabolic process+++GO:0061771///response to caloric restriction+++GO:0061889///negative regulation of astrocyte activation+++GO:0070508///cholesterol import+++GO:0071398///cellular response to fatty acid+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090118///receptor-mediated endocytosis involved in cholesterol transport+++GO:0090181///regulation of cholesterol metabolic process+++GO:0097242///amyloid-beta clearance+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1903979///negative regulation of microglial cell activation+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:1905907///negative regulation of amyloid fibril formation 16840 16840 'Cnmd' mRNA 3895 4186 4058 158.98 168.44 175.77 184.16 194.25 187.3 167.73 188.57 5185 5336 5104 4046.333333 5208.333333 5.55E-08 0.352026356 GO:0005576///extracellular region+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001886///endothelial cell morphogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0007275///multicellular organism development+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0045778///positive regulation of ossification+++GO:0051216///cartilage development 16841 16841 'Lect2' mRNA 14 9 12 0.5 0.29 0.42 0.37 0.38 0.47 0.403333333 0.406666667 13 13 16 11.66666667 14 0.78719672 0.24938459 GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006935///chemotaxis+++GO:0030178///negative regulation of Wnt signaling pathway 16842 16842 'Lef1' mRNA 890 846 803 13.48 12.62 12.85 9.28 10.88 9.29 12.98333333 9.816666667 706 810 692 846.3333333 736 0.065063828 -0.211313037 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04916///Melanogenesis+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05132///Salmonella infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0032993///protein-DNA complex+++GO:1990907///beta-catenin-TCF complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008301///DNA binding, bending+++GO:0030284///estrogen receptor activity+++GO:0030331///estrogen receptor binding+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0045295///gamma-catenin binding+++GO:0070016///armadillo repeat domain binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001649///osteoblast differentiation+++GO:0001756///somitogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001944///vasculature development+++GO:0002040///sprouting angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016055///Wnt signaling pathway+++GO:0021542///dentate gyrus development+++GO:0021766///hippocampus development+++GO:0021861///forebrain radial glial cell differentiation+++GO:0021873///forebrain neuroblast division+++GO:0021943///formation of radial glial scaffolds+++GO:0022407///regulation of cell-cell adhesion+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030223///neutrophil differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030509///BMP signaling pathway+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0030879///mammary gland development+++GO:0032696///negative regulation of interleukin-13 production+++GO:0032713///negative regulation of interleukin-4 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0033153///T cell receptor V(D)J recombination+++GO:0042100///B cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043586///tongue development+++GO:0043923///positive regulation by host of viral transcription+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045063///T-helper 1 cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046632///alpha-beta T cell differentiation+++GO:0048341///paraxial mesoderm formation+++GO:0048468///cell development+++GO:0050909///sensory perception of taste+++GO:0060033///anatomical structure regression+++GO:0060070///canonical Wnt signaling pathway+++GO:0060325///face morphogenesis+++GO:0060326///cell chemotaxis+++GO:0060561///apoptotic process involved in morphogenesis+++GO:0060710///chorio-allantoic fusion+++GO:0061153///trachea gland development+++GO:0062009///secondary palate development+++GO:0071345///cellular response to cytokine stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0071866///negative regulation of apoptotic process in bone marrow+++GO:0071895///odontoblast differentiation+++GO:0071899///negative regulation of estrogen receptor binding+++GO:0090068///positive regulation of cell cycle process+++GO:0097043///histone H3-K56 acetylation+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1902732///positive regulation of chondrocyte proliferation" 16847 16847 'Lepr' mRNA 40.92 45.43 57.95 0.4 0.47 0.59 0.75 0.58 0.72 0.486666667 0.683333333 85.42 65.43 76.08 48.1 75.64333333 0.062508847 0.650559763 04060///Cytokine-cytokine receptor interaction+++04080///Neuroactive ligand-receptor interaction+++04152///AMPK signaling pathway+++04630///JAK-STAT signaling pathway+++04920///Adipocytokine signaling pathway+++04932///Non-alcoholic fatty liver disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0016500///protein-hormone receptor activity+++GO:0017046///peptide hormone binding+++GO:0019955///cytokine binding+++GO:0038021///leptin receptor activity+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0005977///glycogen metabolic process+++GO:0006909///phagocytosis+++GO:0007165///signal transduction+++GO:0008203///cholesterol metabolic process+++GO:0010507///negative regulation of autophagy+++GO:0014009///glial cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0019953///sexual reproduction+++GO:0030217///T cell differentiation+++GO:0033210///leptin-mediated signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042593///glucose homeostasis+++GO:0042755///eating behavior+++GO:0043410///positive regulation of MAPK cascade+++GO:0044321///response to leptin+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046850///regulation of bone remodeling+++GO:0051049///regulation of transport+++GO:0051346///negative regulation of hydrolase activity+++GO:0060259///regulation of feeding behavior+++GO:0097009///energy homeostasis+++GO:0098868///bone growth+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903999///negative regulation of eating behavior+++GO:1904060///negative regulation of locomotor rhythm 16848 16848 'Lfng' mRNA 1581 1559 648 38.88 37.76 16.91 9.94 6.57 8.9 31.18333333 8.47 465 300 403 1262.666667 389.3333333 5.68E-05 -1.694284963 00514///Other types of O-glycan biosynthesis+++04330///Notch signaling pathway+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0033829///O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity+++GO:0046872///metal ion binding" GO:0001541///ovarian follicle development+++GO:0001756///somitogenesis+++GO:0002315///marginal zone B cell differentiation+++GO:0007275///multicellular organism development+++GO:0007386///compartment pattern specification+++GO:0007389///pattern specification process+++GO:0008593///regulation of Notch signaling pathway+++GO:0014807///regulation of somitogenesis+++GO:0030217///T cell differentiation+++GO:0032092///positive regulation of protein binding+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0051446///positive regulation of meiotic cell cycle+++GO:1902367///negative regulation of Notch signaling pathway involved in somitogenesis 16852 16852 'Lgals1' mRNA 965 954 1077 82.17 80.52 97.32 1040.19 1131.71 1043.09 86.67 1071.663333 13982 14813 13537 998.6666667 14110.66667 0 3.806361815 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0005534///galactose binding+++GO:0030246///carbohydrate binding+++GO:0030395///lactose binding+++GO:0042802///identical protein binding+++GO:0043236///laminin binding GO:0002317///plasma cell differentiation+++GO:0006915///apoptotic process+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010977///negative regulation of neuron projection development+++GO:0031295///T cell costimulation+++GO:0034120///positive regulation of erythrocyte aggregation+++GO:0035900///response to isolation stress+++GO:0042493///response to drug+++GO:0045185///maintenance of protein location+++GO:0045445///myoblast differentiation+++GO:0046598///positive regulation of viral entry into host cell+++GO:0048678///response to axon injury+++GO:0071333///cellular response to glucose stimulus+++GO:0071407///cellular response to organic cyclic compound 16854 16854 'Lgals3' mRNA 404 396 409 17.39 16.74 18.57 705.29 734.69 701.47 17.56666667 713.8166667 18901 19211 18200 403 18770.66667 0 5.529883277 GO:0001772///immunological synapse+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0044216///other organism cell+++GO:0062023///collagen-containing extracellular matrix+++GO:0097386///glial cell projection GO:0005515///protein binding+++GO:0019863///IgE binding+++GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0034988///Fc-gamma receptor I complex binding+++GO:0042056///chemoattractant activity+++GO:0043236///laminin binding+++GO:0048029///monosaccharide binding+++GO:0048030///disaccharide binding+++GO:0050785///advanced glycation end-product receptor activity+++GO:0070492///oligosaccharide binding GO:0001501///skeletal system development+++GO:0002376///immune system process+++GO:0002548///monocyte chemotaxis+++GO:0006397///mRNA processing+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0014064///positive regulation of serotonin secretion+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030593///neutrophil chemotaxis+++GO:0030855///epithelial cell differentiation+++GO:0031334///positive regulation of protein complex assembly+++GO:0031640///killing of cells of other organism+++GO:0042129///regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045185///maintenance of protein location+++GO:0045766///positive regulation of angiogenesis+++GO:0045806///negative regulation of endocytosis+++GO:0048245///eosinophil chemotaxis+++GO:0048246///macrophage chemotaxis+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050918///positive chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070232///regulation of T cell apoptotic process+++GO:0071674///mononuclear cell migration+++GO:0071677///positive regulation of mononuclear cell migration+++GO:0090280///positive regulation of calcium ion import+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903769///negative regulation of cell proliferation in bone marrow+++GO:2000521///negative regulation of immunological synapse formation+++GO:2001189///negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 16855 16855 'Lgals4' mRNA 1967.42 1806.49 2011.72 66.67 61.05 72.5 16.8 18.83 16.75 66.74 17.46 594.23 620 571.97 1928.543333 595.4 5.90E-73 -1.710383241 GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0016936///galactoside binding+++GO:0030246///carbohydrate binding 16858 16858 'Lgals7' mRNA 3 2 4 0.39 0.26 0.42 0.45 0.93 1.08 0.356666667 0.82 4 8 10 3 7.333333333 0.31240168 1.274062135 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016936///galactoside binding+++GO:0030246///carbohydrate binding "GO:0006915///apoptotic process+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0010628///positive regulation of gene expression+++GO:0032689///negative regulation of interferon-gamma production+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation" 16859 16859 'Lgals9' mRNA 1265 1342 1288 49.84 52.18 53.89 154.15 156.57 151.16 51.97 153.96 4479 4442 4250 1298.333333 4390.333333 8.50E-156 1.745714047 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016936///galactoside binding+++GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0048030///disaccharide binding "GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0006935///chemotaxis+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007565///female pregnancy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010819///regulation of T cell chemotaxis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032722///positive regulation of chemokine production+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0032823///regulation of natural killer cell differentiation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0043032///positive regulation of macrophage activation+++GO:0043322///negative regulation of natural killer cell degranulation+++GO:0045089///positive regulation of innate immune response+++GO:0045185///maintenance of protein location+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0098586///cellular response to virus+++GO:1900426///positive regulation of defense response to bacterium+++GO:2000316///regulation of T-helper 17 type immune response+++GO:2000406///positive regulation of T cell migration+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2000679///positive regulation of transcription regulatory region DNA binding" 16865 16865 'Eif2d' mRNA 1274.11 1364.74 1262.03 29.71 30.34 31.83 26.53 27.51 28.37 30.62666667 27.47 1282.57 1230.02 1291.73 1300.293333 1268.106667 0.650730127 -0.047783075 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly+++GO:0075522///IRES-dependent viral translational initiation 16866 16866 'Lhb' mRNA 464 496 398 9.02 8.58 9.27 0.48 0.52 0.61 8.956666667 0.536666667 29 19 37 452.6666667 28.33333333 1.56E-72 -4.006781831 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04917///Prolactin signaling pathway+++04929///GnRH secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005179///hormone activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0035471///luteinizing hormone signaling pathway involved in ovarian follicle development 16867 16867 'Lhcgr' mRNA 20.13 28 14.18 0.21 0.29 0.18 0.18 0.16 0.16 0.226666667 0.166666667 13 12 15.12 20.77 13.37333333 0.366330114 -0.6334193 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04913///Ovarian steroidogenesis+++04917///Prolactin signaling pathway GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031233///intrinsic component of external side of plasma membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0004964///luteinizing hormone receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016500///protein-hormone receptor activity+++GO:0017046///peptide hormone binding+++GO:0035472///choriogonadotropin hormone receptor activity+++GO:0038106///choriogonadotropin hormone binding+++GO:0042802///identical protein binding+++GO:0051117///ATPase binding GO:0001541///ovarian follicle development+++GO:0006622///protein targeting to lysosome+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009755///hormone-mediated signaling pathway+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0022602///ovulation cycle process+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0034699///response to luteinizing hormone+++GO:0042700///luteinizing hormone signaling pathway+++GO:0046544///development of secondary male sexual characteristics+++GO:0046886///positive regulation of hormone biosynthetic process+++GO:0050482///arachidonic acid secretion+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050890///cognition+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060065///uterus development+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0072520///seminiferous tubule development+++GO:0090030///regulation of steroid hormone biosynthetic process 16869 16869 'Lhx1' mRNA 28 15 12 0.36 0.19 0.17 0.17 0.14 0.05 0.24 0.12 15 12 4 18.33333333 10.33333333 0.308542864 -0.833876164 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001702///gastrulation with mouth forming second+++GO:0001705///ectoderm formation+++GO:0001706///endoderm formation+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007492///endoderm development+++GO:0008045///motor neuron axon guidance+++GO:0009653///anatomical structure morphogenesis+++GO:0009791///post-embryonic development+++GO:0009880///embryonic pattern specification+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010468///regulation of gene expression+++GO:0010842///retina layer formation+++GO:0021510///spinal cord development+++GO:0021517///ventral spinal cord development+++GO:0021527///spinal cord association neuron differentiation+++GO:0021537///telencephalon development+++GO:0021549///cerebellum development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021871///forebrain regionalization+++GO:0021937///cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0032525///somite rostral/caudal axis specification+++GO:0035502///metanephric part of ureteric bud development+++GO:0035846///oviduct epithelium development+++GO:0035847///uterine epithelium development+++GO:0035849///nephric duct elongation+++GO:0035852///horizontal cell localization+++GO:0040019///positive regulation of embryonic development+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048382///mesendoderm development+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048793///pronephros development+++GO:0060041///retina development in camera-type eye+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060065///uterus development+++GO:0060066///oviduct development+++GO:0060067///cervix development+++GO:0060068///vagina development+++GO:0060322///head development+++GO:0060429///epithelium development+++GO:0061205///paramesonephric duct development+++GO:0072049///comma-shaped body morphogenesis+++GO:0072050///S-shaped body morphogenesis+++GO:0072077///renal vesicle morphogenesis+++GO:0072164///mesonephric tubule development+++GO:0072177///mesonephric duct development+++GO:0072178///nephric duct morphogenesis+++GO:0072197///ureter morphogenesis+++GO:0072224///metanephric glomerulus development+++GO:0072278///metanephric comma-shaped body morphogenesis+++GO:0072283///metanephric renal vesicle morphogenesis+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0090009///primitive streak formation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0097477///lateral motor column neuron migration+++GO:2000543///positive regulation of gastrulation+++GO:2000744///positive regulation of anterior head development+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation" 16870 16870 'Lhx2' mRNA 1 0 0 0.03 0 0 0.05 0 0.11 0.01 0.053333333 2 0 4 0.333333333 2 0.42363412 2.46375069 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007498///mesoderm development+++GO:0009953///dorsal/ventral pattern formation+++GO:0021537///telencephalon development+++GO:0021772///olfactory bulb development+++GO:0021978///telencephalon regionalization+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048675///axon extension+++GO:0050768///negative regulation of neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000678///negative regulation of transcription regulatory region DNA binding" 16871 16871 'Lhx3' mRNA 1546 1627 1498 40.33 42.31 41.51 4.06 4.53 4.04 41.38333333 4.21 178 195 167 1557 180 4.34E-189 -3.123493168 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0001890///placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008045///motor neuron axon guidance+++GO:0009953///dorsal/ventral pattern formation+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0021521///ventral spinal cord interneuron specification+++GO:0021526///medial motor column neuron differentiation+++GO:0021527///spinal cord association neuron differentiation+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development" 16872 16872 'Lhx4' mRNA 1 3 0 0.01 0.03 0 0 0.02 0 0.013333333 0.006666667 0 2 0 1.333333333 0.666666667 0.800369356 -0.95477495 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001890///placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008045///motor neuron axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0021526///medial motor column neuron differentiation+++GO:0030182///neuron differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 16874 16874 'Lhx6' mRNA 4 5 1 0.07 0.08 0.02 0.12 0.09 0.12 0.056666667 0.11 8 6 8 3.333333333 7.333333333 0.366079887 1.142554763 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021800///cerebral cortex tangential migration+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0021877///forebrain neuron fate commitment+++GO:0021884///forebrain neuron development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0048469///cell maturation" 16876 16876 'Lhx9' mRNA 1 0 0 0.03 0 0 0.01 0 0 0.01 0.003333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0030182///neuron differentiation+++GO:0035262///gonad morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0097380///dorsal spinal cord interneuron anterior axon guidance" 16878 16878 'Lif' mRNA 24 18 28 0.32 0.24 0.39 1.37 1.33 1.22 0.316666667 1.306666667 117 112 102 23.33333333 110.3333333 1.27E-11 2.224393744 04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04668///TNF signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005146///leukemia inhibitory factor receptor binding+++GO:0008083///growth factor activity GO:0001974///blood vessel remodeling+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0007566///embryo implantation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0016525///negative regulation of angiogenesis+++GO:0019827///stem cell population maintenance+++GO:0030324///lung development+++GO:0031100///animal organ regeneration+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043410///positive regulation of MAPK cascade+++GO:0045595///regulation of cell differentiation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046697///decidualization+++GO:0046888///negative regulation of hormone secretion+++GO:0048286///lung alveolus development+++GO:0048644///muscle organ morphogenesis+++GO:0048666///neuron development+++GO:0048708///astrocyte differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048861///leukemia inhibitory factor signaling pathway+++GO:0048863///stem cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051461///positive regulation of corticotropin secretion+++GO:0060041///retina development in camera-type eye+++GO:0060135///maternal process involved in female pregnancy+++GO:0060290///transdifferentiation+++GO:0060426///lung vasculature development+++GO:0060463///lung lobe morphogenesis+++GO:0060707///trophoblast giant cell differentiation+++GO:0060708///spongiotrophoblast differentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0072108///positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901676///positive regulation of histone H3-K27 acetylation+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding 16880 16880 'Lifr' mRNA 2416.22 2390.02 2255.41 16.94 16.93 15.8 19.81 18.84 18.97 16.55666667 19.20666667 2949.53 2729.83 2782.16 2353.883333 2820.506667 1.18E-04 0.249082918 04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004923///leukemia inhibitory factor receptor activity+++GO:0004924///oncostatin-M receptor activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0019955///cytokine binding GO:0008284///positive regulation of cell proliferation+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031100///animal organ regeneration+++GO:0034097///response to cytokine+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0048812///neuron projection morphogenesis+++GO:0048861///leukemia inhibitory factor signaling pathway+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway 16881 16881 'Lig1' mRNA 264.93 242.98 241.46 4.67 4.19 4.49 9.6 9.01 10.03 4.45 9.546666667 628.15 572.74 631 249.79 610.63 1.23E-24 1.281457721 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003909///DNA ligase activity+++GO:0003910///DNA ligase (ATP) activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006266///DNA ligation+++GO:0006273///lagging strand elongation+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0042542///response to hydrogen peroxide+++GO:0051301///cell division+++GO:0071897///DNA biosynthetic process+++GO:1903461///Okazaki fragment processing involved in mitotic DNA replication 16882 16882 'Lig3' mRNA 808.64 760.61 847.61 7.19 6.71 7.99 4.71 5.43 5.26 7.296666667 5.133333333 605.62 683.85 654.88 805.62 648.1166667 0.005851123 -0.327857399 03410///Base excision repair GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0070421///DNA ligase III-XRCC1 complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003909///DNA ligase activity+++GO:0003910///DNA ligase (ATP) activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding "GO:0006260///DNA replication+++GO:0006266///DNA ligation+++GO:0006273///lagging strand elongation+++GO:0006281///DNA repair+++GO:0006288///base-excision repair, DNA ligation+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007005///mitochondrion organization+++GO:0007049///cell cycle+++GO:0043504///mitochondrial DNA repair+++GO:0045910///negative regulation of DNA recombination+++GO:0051301///cell division+++GO:0071897///DNA biosynthetic process+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:0097681///double-strand break repair via alternative nonhomologous end joining" 16885 16885 'Limk1' mRNA 32 37 8 0.54 0.6 0.15 0.68 0.35 0.87 0.43 0.633333333 45 23 56 25.66666667 41.33333333 0.257149149 0.694752085 04360///Axon guidance+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0045773///positive regulation of axon extension+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051496///positive regulation of stress fiber assembly 16886 16886 'Limk2' mRNA 4098 4215 4226 57.08 58.08 62.72 34.67 35.29 32.61 59.29333333 34.19 2903 2894 2668 4179.666667 2821.666667 1.39E-17 -0.579936542 04360///Axon guidance+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005801///cis-Golgi network+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030953///astral microtubule organization+++GO:0051650///establishment of vesicle localization+++GO:0060322///head development+++GO:0061303///cornea development in camera-type eye+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902018///negative regulation of cilium assembly 16889 16889 'Lipa' mRNA 630 647 651 11.66 11.78 12.78 40.87 42.48 41.12 12.07333333 41.49 2541 2580 2476 642.6666667 2532.333333 1.80E-136 1.966087986 00100///Steroid biosynthesis+++04142///Lysosome+++04979///Cholesterol metabolism GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds" GO:0000902///cell morphogenesis+++GO:0001816///cytokine production+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006954///inflammatory response+++GO:0008283///cell proliferation+++GO:0016042///lipid catabolic process+++GO:0016125///sterol metabolic process+++GO:0030324///lung development+++GO:0048771///tissue remodeling+++GO:0048873///homeostasis of number of cells within a tissue 16890 16890 'Lipe' mRNA 543 559 429 10.19 10.19 8.26 9.25 8.18 8.78 9.546666667 8.736666667 547 475 512 510.3333333 511.3333333 0.979686807 -0.005322319 04024///cAMP signaling pathway+++04152///AMPK signaling pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0005515///protein binding+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017171///serine hydrolase activity+++GO:0019901///protein kinase binding+++GO:0033878///hormone-sensitive lipase activity+++GO:0042134///rRNA primary transcript binding+++GO:0047372///acylglycerol lipase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0050253///retinyl-palmitate esterase activity+++GO:0102258///1,3-diacylglycerol acylhydrolase activity+++GO:0102259///1,2-diacylglycerol acylhydrolase activity" GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0042572///retinol metabolic process+++GO:0042758///long-chain fatty acid catabolic process+++GO:0046340///diacylglycerol catabolic process+++GO:0046485///ether lipid metabolic process+++GO:0070417///cellular response to cold 16891 16891 'Lipg' mRNA 13 8 1 0.2 0.11 0.02 0.29 0.22 0.23 0.11 0.246666667 23 17 18 7.333333333 19.33333333 0.089628134 1.405809017 00561///Glycerolipid metabolism+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface GO:0004465///lipoprotein lipase activity+++GO:0004620///phospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0008201///heparin binding+++GO:0008970///phospholipase A1 activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007584///response to nutrient+++GO:0008283///cell proliferation+++GO:0010983///positive regulation of high-density lipoprotein particle clearance+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0032376///positive regulation of cholesterol transport+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0050746///regulation of lipoprotein metabolic process+++GO:0055091///phospholipid homeostasis 16897 16897 'Llgl1' mRNA 1255 1299 1164 15.66 15.97 15.33 11.67 12.27 11.89 15.65333333 11.94333333 1058 1105 1056 1239.333333 1073 0.013178837 -0.217813641 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0030864///cortical actin cytoskeleton+++GO:0031901///early endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0035748///myelin sheath abaxonal region+++GO:0042995///cell projection GO:0005096///GTPase activator activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0045159///myosin II binding GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0008593///regulation of Notch signaling pathway+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032878///regulation of establishment or maintenance of cell polarity+++GO:0035090///maintenance of apical/basal cell polarity+++GO:0050708///regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0051294///establishment of spindle orientation+++GO:0065003///protein-containing complex assembly 16898 16898 'Rps2' mRNA 6060.95 6351.86 5430.5 387.99 402.12 368.86 564.6 642.8 633.29 386.3233333 613.5633333 10111.95 11220.97 10960.71 5947.77 10764.54333 4.50E-41 0.847974024 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0017134///fibroblast growth factor binding+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding GO:0000028///ribosomal small subunit assembly+++GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0071353///cellular response to interleukin-4 16904 16904 'Gzmm' mRNA 28 25 25 1.64 1.36 1.56 1.8 1.79 1.64 1.52 1.743333333 34 35 26 26 31.66666667 0.639410375 0.272879554 GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001913///T cell mediated cytotoxicity+++GO:0006508///proteolysis+++GO:0008219///cell death 16905 16905 'Lmna' mRNA 2544 2444 2562 49.27 48.58 52.73 107.01 106.94 106.89 50.19333333 106.9466667 6402 6296 6130 2516.666667 6276 3.91E-93 1.304920865 04210///Apoptosis+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005638///lamin filament+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0035861///site of double-strand break+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0042802///identical protein binding GO:0006606///protein import into nucleus+++GO:0006997///nucleus organization+++GO:0006998///nuclear envelope organization+++GO:0007517///muscle organ development+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030010///establishment of cell polarity+++GO:0030334///regulation of cell migration+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0031647///regulation of protein stability+++GO:0032204///regulation of telomere maintenance+++GO:0034504///protein localization to nucleus+++GO:0034613///cellular protein localization+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0055015///ventricular cardiac muscle cell development+++GO:0071456///cellular response to hypoxia+++GO:0072201///negative regulation of mesenchymal cell proliferation+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090343///positive regulation of cell aging+++GO:1900114///positive regulation of histone H3-K9 trimethylation+++GO:1900180///regulation of protein localization to nucleus+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress+++GO:1904178///negative regulation of adipose tissue development+++GO:1990683///DNA double-strand break attachment to nuclear envelope+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 16906 16906 'Lmnb1' mRNA 172 153 122 3.34 2.92 2.51 5.65 5.25 6.09 2.923333333 5.663333333 335 304 350 149 329.6666667 2.62E-11 1.137823528 04210///Apoptosis+++04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005638///lamin filament+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0031965///nuclear membrane GO:0003690///double-stranded DNA binding+++GO:0008432///JUN kinase binding+++GO:0043274///phospholipase binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0046330///positive regulation of JNK cascade+++GO:1904609///cellular response to monosodium L-glutamate 16907 16907 'Lmnb2' mRNA 430 523 507 6.95 8.32 8.7 8.91 8.3 9.1 7.99 8.77 634 577 627 486.6666667 612.6666667 0.014119536 0.318345142 04210///Apoptosis+++04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005638///lamin filament+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0042802///identical protein binding 16909 16909 'Lmo2' mRNA 117 107 39 4.43 4.02 1.57 6.69 9.63 9.3 3.34 8.54 199 283 271 87.66666667 251 1.42E-07 1.526803479 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001221///transcription cofactor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0035162///embryonic hemopoiesis+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097067///cellular response to thyroid hormone stimulus 16911 16911 'Lmo4' mRNA 369 376 321 13.46 13.71 12.69 11.66 10.26 11.18 13.28666667 11.03333333 351 310 331 355.3333333 330.6666667 0.497271824 -0.11391858 GO:0005634///nucleus+++GO:0031252///cell leading edge+++GO:0090575///RNA polymerase II transcription factor complex GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding GO:0001843///neural tube closure+++GO:0003281///ventricular septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021514///ventral spinal cord interneuron differentiation+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021527///spinal cord association neuron differentiation+++GO:0030334///regulation of cell migration+++GO:0031333///negative regulation of protein complex assembly+++GO:0033674///positive regulation of kinase activity+++GO:0042659///regulation of cell fate specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048538///thymus development+++GO:0050865///regulation of cell activation 16912 16912 'Psmb9' mRNA 406 399 395 31.99 31.84 32.78 96.52 106.68 105.81 32.20333333 103.0033333 1392 1492 1459 400 1447.666667 2.46E-83 1.844653057 03050///Proteasome "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:1990111///spermatoproteasome complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0070628///proteasome binding GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0009617///response to bacterium+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0019882///antigen processing and presentation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:2000116///regulation of cysteine-type endopeptidase activity 16913 16913 'Psmb8' mRNA 606 675 666 30.32 33.35 35.35 128.82 125.2 128.08 33.00666667 127.3666667 2955 2801 2841 649 2865.666667 7.09E-160 2.129569397 03050///Proteasome "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:1990111///spermatoproteasome complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0019882///antigen processing and presentation+++GO:0030154///cell differentiation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045444///fat cell differentiation+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0052548///regulation of endopeptidase activity 16917 16917 'Lmx1b' mRNA 13 29 15 0.13 0.28 0.16 0.02 0.03 0.01 0.19 0.02 2 3 1 19 2 7.20E-04 -3.249395754 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001764///neuron migration+++GO:0002930///trabecular meshwork development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008283///cell proliferation+++GO:0009953///dorsal/ventral pattern formation+++GO:0010468///regulation of gene expression+++GO:0010506///regulation of autophagy+++GO:0021587///cerebellum morphogenesis+++GO:0021954///central nervous system neuron development+++GO:0030182///neuron differentiation+++GO:0030199///collagen fibril organization+++GO:0030326///embryonic limb morphogenesis+++GO:0030901///midbrain development+++GO:0032386///regulation of intracellular transport+++GO:0035108///limb morphogenesis+++GO:0035265///organ growth+++GO:0042048///olfactory behavior+++GO:0043010///camera-type eye development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050808///synapse organization+++GO:0071542///dopaminergic neuron differentiation" 16918 16918 'Mycl' mRNA 232 263 194 3.79 4.25 3.38 0.93 0.98 1.35 3.806666667 1.086666667 65 67 91 229.6666667 74.33333333 1.20E-13 -1.633424036 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045607///regulation of inner ear auditory receptor cell differentiation" 16922 16922 'Phyh' mRNA 4372 4461 4581 175.74 176.88 195.36 145.09 146.01 145.28 182.66 145.46 4146 4071 4016 4471.333333 4077.666667 0.03833072 -0.14659105 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0097731///9+0 non-motile cilium GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0031406///carboxylic acid binding+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0048244///phytanoyl-CoA dioxygenase activity+++GO:0051213///dioxygenase activity GO:0001561///fatty acid alpha-oxidation+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006720///isoprenoid metabolic process+++GO:0019606///2-oxobutyrate catabolic process+++GO:0097089///methyl-branched fatty acid metabolic process 16923 16923 'Sh2b3' mRNA 649.28 592.4 541.23 8.51 7.67 7.57 12.06 11.26 12.79 7.916666667 12.03666667 1065.77 975.55 1094.43 594.3033333 1045.25 3.10E-16 0.804224753 04722///Neurotrophin signaling pathway GO:0005886///plasma membrane GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0035591///signaling adaptor activity+++GO:0042301///phosphate ion binding+++GO:0044877///protein-containing complex binding+++GO:1990782///protein tyrosine kinase binding GO:0001780///neutrophil homeostasis+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0035162///embryonic hemopoiesis+++GO:0035556///intracellular signal transduction+++GO:0035702///monocyte homeostasis+++GO:0035855///megakaryocyte development+++GO:0036016///cellular response to interleukin-3+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048821///erythrocyte development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:0090331///negative regulation of platelet aggregation+++GO:1900235///negative regulation of Kit signaling pathway+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1990869///cellular response to chemokine 16924 16924 'Lnx1' mRNA 934.3 990.23 927.72 13.13 14.51 14.76 7.14 7 7.74 14.13333333 7.293333333 589.17 546.87 588.71 950.75 574.9166667 1.90E-14 -0.738435024 GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 16939 16939 'Lor' mRNA 10 10 3 0.32 0.32 0.1 0.06 0.09 0.23 0.246666667 0.126666667 2 3 8 7.666666667 4.333333333 0.533901926 -0.811498317 GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane GO:0005200///structural constituent of cytoskeleton+++GO:0030280///structural constituent of epidermis GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization 16948 16948 'Lox' mRNA 210 240 243 2.37 2.72 2.95 38.03 35.36 36.48 2.68 36.62333333 3818 3528 3532 231 3626 0 3.959441457 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix "GO:0004720///protein-lysine 6-oxidase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0016491///oxidoreductase activity+++GO:0016641///oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor+++GO:0046872///metal ion binding" GO:0001568///blood vessel development+++GO:0001649///osteoblast differentiation+++GO:0001932///regulation of protein phosphorylation+++GO:0007507///heart development+++GO:0009725///response to hormone+++GO:0010468///regulation of gene expression+++GO:0016202///regulation of striated muscle tissue development+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0018057///peptidyl-lysine oxidation+++GO:0018158///protein oxidation+++GO:0030199///collagen fibril organization+++GO:0030282///bone mineralization+++GO:0030324///lung development+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0035904///aorta development+++GO:0035905///ascending aorta development+++GO:0035906///descending aorta development+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0046716///muscle cell cellular homeostasis+++GO:0048251///elastic fiber assembly+++GO:0048514///blood vessel morphogenesis+++GO:0048545///response to steroid hormone+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0060326///cell chemotaxis+++GO:0061448///connective tissue development+++GO:0071310///cellular response to organic substance+++GO:0071897///DNA biosynthetic process+++GO:1900120///regulation of receptor binding+++GO:1903010///regulation of bone development+++GO:1990869///cellular response to chemokine+++GO:2000586///regulation of platelet-derived growth factor receptor-beta signaling pathway 16949 16949 'Loxl1' mRNA 1528 1479 1370 24.97 23.78 23.75 31.81 32.33 31.74 24.16666667 31.96 2240 2224 2165 1459 2209.666667 3.54E-17 0.588336582 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix "GO:0004720///protein-lysine 6-oxidase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016641///oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor+++GO:0046872///metal ion binding" GO:0018057///peptidyl-lysine oxidation+++GO:0030199///collagen fibril organization+++GO:0032496///response to lipopolysaccharide+++GO:0035904///aorta development 16950 16950 'Loxl3' mRNA 400.55 386.38 372 5.31 5.04 5.23 7.25 7.09 6.84 5.193333333 7.06 629.81 601.58 575.51 386.31 602.3 6.17E-08 0.628694154 GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix "GO:0001968///fibronectin binding+++GO:0004720///protein-lysine 6-oxidase activity+++GO:0005044///scavenger receptor activity+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0016641///oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor+++GO:0046872///metal ion binding+++GO:0070492///oligosaccharide binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001837///epithelial to mesenchymal transition+++GO:0001935///endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0006325///chromatin organization+++GO:0006464///cellular protein modification process+++GO:0006897///endocytosis+++GO:0006954///inflammatory response+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0018057///peptidyl-lysine oxidation+++GO:0021510///spinal cord development+++GO:0030199///collagen fibril organization+++GO:0030324///lung development+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0043542///endothelial cell migration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046688///response to copper ion+++GO:0060021///roof of mouth development+++GO:0061053///somite development+++GO:0070828///heterochromatin organization+++GO:1902455///negative regulation of stem cell population maintenance+++GO:1905590///fibronectin fibril organization+++GO:2000329///negative regulation of T-helper 17 cell lineage commitment+++GO:2001046///positive regulation of integrin-mediated signaling pathway" 16952 16952 'Anxa1' mRNA 2349 2360 2424 100.65 99.78 110.19 921.3 995.28 914.66 103.54 943.7466667 24692 26024 23712 2377.666667 24809.33333 0 3.370601735 GO:0001533///cornified envelope+++GO:0001891///phagocytic cup+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0031901///early endosome membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042629///mast cell granule+++GO:0042995///cell projection+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0097060///synaptic membrane GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004859///phospholipase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019834///phospholipase A2 inhibitor activity+++GO:0036121///double-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:1990814///DNA/DNA annealing activity "GO:0001780///neutrophil homeostasis+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002548///monocyte chemotaxis+++GO:0002685///regulation of leukocyte migration+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0008360///regulation of cell shape+++GO:0009725///response to hormone+++GO:0010165///response to X-ray+++GO:0014070///response to organic cyclic compound+++GO:0014839///myoblast migration involved in skeletal muscle regeneration+++GO:0018149///peptide cross-linking+++GO:0030073///insulin secretion+++GO:0030216///keratinocyte differentiation+++GO:0030850///prostate gland development+++GO:0031018///endocrine pancreas development+++GO:0031340///positive regulation of vesicle fusion+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0031532///actin cytoskeleton reorganization+++GO:0031960///response to corticosteroid+++GO:0032355///response to estradiol+++GO:0032508///DNA duplex unwinding+++GO:0032652///regulation of interleukin-1 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0042063///gliogenesis+++GO:0042102///positive regulation of T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043434///response to peptide hormone+++GO:0044849///estrous cycle+++GO:0045087///innate immune response+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0045920///negative regulation of exocytosis+++GO:0046632///alpha-beta T cell differentiation+++GO:0046883///regulation of hormone secretion+++GO:0050482///arachidonic acid secretion+++GO:0050709///negative regulation of protein secretion+++GO:0050727///regulation of inflammatory response+++GO:0051384///response to glucocorticoid+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070365///hepatocyte differentiation+++GO:0070459///prolactin secretion+++GO:0070555///response to interleukin-1+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071621///granulocyte chemotaxis+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090303///positive regulation of wound healing+++GO:0097350///neutrophil clearance+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1900138///negative regulation of phospholipase A2 activity" 16956 16956 'Lpl' mRNA 597.61 649.61 545.92 7.96 8.51 7.72 28.32 28.32 26.68 8.063333333 27.77333333 2446.83 2390.2 2232.45 597.7133333 2356.493333 2.67E-132 1.970788379 00561///Glycerolipid metabolism+++03320///PPAR signaling pathway+++04979///Cholesterol metabolism+++05010///Alzheimer disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0042627///chylomicron GO:0004465///lipoprotein lipase activity+++GO:0004620///phospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008970///phospholipase A1 activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0017129///triglyceride binding+++GO:0034185///apolipoprotein binding+++GO:0042803///protein homodimerization activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0071813///lipoprotein particle binding GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0009409///response to cold+++GO:0009617///response to bacterium+++GO:0009749///response to glucose+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010886///positive regulation of cholesterol storage+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0016042///lipid catabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0019433///triglyceride catabolic process+++GO:0031670///cellular response to nutrient+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034371///chylomicron remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0070328///triglyceride homeostasis+++GO:0071398///cellular response to fatty acid+++GO:1900077///negative regulation of cellular response to insulin stimulus+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 16963 16963 'Xcl1' mRNA 1 0 2 0.16 0 0.34 1.12 0.87 0.73 0.166666667 0.906666667 8 6 5 1 6.333333333 0.095222981 2.628510483 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0042379///chemokine receptor binding+++GO:0042803///protein homodimerization activity+++GO:0048020///CCR chemokine receptor binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002548///monocyte chemotaxis+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0002725///negative regulation of T cell cytokine production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0002839///positive regulation of immune response to tumor cell+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0009615///response to virus+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0035782///mature natural killer cell chemotaxis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045089///positive regulation of innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048247///lymphocyte chemotaxis+++GO:0050727///regulation of inflammatory response+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071353///cellular response to interleukin-4+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0071663///positive regulation of granzyme B production+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:2000412///positive regulation of thymocyte migration+++GO:2000503///positive regulation of natural killer cell chemotaxis+++GO:2000513///positive regulation of granzyme A production+++GO:2000518///negative regulation of T-helper 1 cell activation+++GO:2000538///positive regulation of B cell chemotaxis+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:2000556///positive regulation of T-helper 1 cell cytokine production+++GO:2000558///positive regulation of immunoglobulin production in mucosal tissue+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2000566///positive regulation of CD8-positive, alpha-beta T cell proliferation" 16969 16969 'Zbtb7a' mRNA 2004 2044 1422 19.23 19.27 14.48 12.66 13.11 14.73 17.66 13.5 1522 1540 1713 1823.333333 1591.666667 0.080739051 -0.19979228 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016581///NuRD complex+++GO:0035861///site of double-strand break+++GO:0070418///DNA-dependent protein kinase complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0033613///activating transcription factor binding+++GO:0035035///histone acetyltransferase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006110///regulation of glycolytic process+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034504///protein localization to nucleus+++GO:0042981///regulation of apoptotic process+++GO:0043249///erythrocyte maturation+++GO:0045444///fat cell differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051216///cartilage development+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0097680///double-strand break repair via classical nonhomologous end joining+++GO:2000677///regulation of transcription regulatory region DNA binding" 16970 16970 'Lrmp' mRNA 37 58 43 1.01 1.49 1.29 10.91 10.49 10.2 1.263333333 10.53333333 529 498 478 46 501.6666667 2.02E-73 3.436675921 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0002376///immune system process+++GO:0006997///nucleus organization+++GO:0007338///single fertilization 16971 16971 'Lrp1' mRNA 10218 9671 8646 35.68 33.18 32.02 68.86 64.11 67.46 33.62666667 66.81 22716 20669 21563 9511.666667 21649.33333 3.33E-111 1.176359815 04979///Cholesterol metabolism+++05010///Alzheimer disease+++05144///Malaria GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030425///dendrite+++GO:0032593///insulin-responsive compartment+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0044295///axonal growth cone+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0016964///alpha-2 macroglobulin receptor activity+++GO:0032050///clathrin heavy chain binding+++GO:0034185///apolipoprotein binding+++GO:0038024///cargo receptor activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0002265///astrocyte activation involved in immune response+++GO:0003279///cardiac septum development+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006909///phagocytosis+++GO:0007041///lysosomal transport+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0008203///cholesterol metabolic process+++GO:0008283///cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010942///positive regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0021987///cerebral cortex development+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032370///positive regulation of lipid transport+++GO:0032374///regulation of cholesterol transport+++GO:0032429///regulation of phospholipase A2 activity+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0035909///aorta morphogenesis+++GO:0042157///lipoprotein metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043277///apoptotic cell clearance+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044242///cellular lipid catabolic process+++GO:0045773///positive regulation of axon extension+++GO:0045807///positive regulation of endocytosis+++GO:0048691///positive regulation of axon extension involved in regeneration+++GO:0048694///positive regulation of collateral sprouting of injured axon+++GO:0050766///positive regulation of phagocytosis+++GO:0051222///positive regulation of protein transport+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060548///negative regulation of cell death+++GO:0060976///coronary vasculature development+++GO:0061642///chemoattraction of axon+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097242///amyloid-beta clearance+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1900149///positive regulation of Schwann cell migration+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904109///positive regulation of cholesterol import+++GO:1904300///positive regulation of transcytosis+++GO:1904646///cellular response to amyloid-beta+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1905109///regulation of pulmonary blood vessel remodeling+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway 16973 16973 'Lrp5' mRNA 116 122 56 1.2 1.24 0.61 1.01 0.77 1.39 1.016666667 1.056666667 113 84 150 98 115.6666667 0.529762717 0.24041207 "04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05200///Pathways in cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0017147///Wnt-protein binding+++GO:0042813///Wnt-activated receptor activity+++GO:0071936///coreceptor activity involved in Wnt signaling pathway "GO:0001702///gastrulation with mouth forming second+++GO:0001944///vasculature development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002076///osteoblast development+++GO:0006007///glucose catabolic process+++GO:0006897///endocytosis+++GO:0007275///multicellular organism development+++GO:0008203///cholesterol metabolic process+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0009314///response to radiation+++GO:0009952///anterior/posterior pattern specification+++GO:0016055///Wnt signaling pathway+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0035019///somatic stem cell population maintenance+++GO:0035108///limb morphogenesis+++GO:0035426///extracellular matrix-cell signaling+++GO:0042074///cell migration involved in gastrulation+++GO:0042632///cholesterol homeostasis+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046849///bone remodeling+++GO:0048539///bone marrow development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060033///anatomical structure regression+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060070///canonical Wnt signaling pathway+++GO:0060348///bone development+++GO:0060349///bone morphogenesis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060603///mammary gland duct morphogenesis+++GO:0060612///adipose tissue development+++GO:0060764///cell-cell signaling involved in mammary gland development+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0061304///retinal blood vessel morphogenesis+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering" 16974 16974 'Lrp6' mRNA 1422 1483 1354 8.3 8.54 8.52 7.53 6.5 7.18 8.453333333 7.07 1466 1230 1349 1419.666667 1348.333333 0.378936282 -0.086538397 "04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05200///Pathways in cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:1990851///Wnt-Frizzled-LRP5/6 complex+++GO:1990909///Wnt signalosome GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0017147///Wnt-protein binding+++GO:0019210///kinase inhibitor activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0034185///apolipoprotein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042813///Wnt-activated receptor activity+++GO:0071936///coreceptor activity involved in Wnt signaling pathway "GO:0001702///gastrulation with mouth forming second+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001947///heart looping+++GO:0002009///morphogenesis of an epithelium+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003344///pericardium morphogenesis+++GO:0003401///axis elongation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0006897///endocytosis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0009880///embryonic pattern specification+++GO:0009950///dorsal/ventral axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010976///positive regulation of neuron projection development+++GO:0014029///neural crest formation+++GO:0014033///neural crest cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0021587///cerebellum morphogenesis+++GO:0021794///thalamus development+++GO:0021795///cerebral cortex cell migration+++GO:0021861///forebrain radial glial cell differentiation+++GO:0021872///forebrain generation of neurons+++GO:0021874///Wnt signaling pathway involved in forebrain neuroblast division+++GO:0021915///neural tube development+++GO:0021943///formation of radial glial scaffolds+++GO:0021987///cerebral cortex development+++GO:0030278///regulation of ossification+++GO:0030326///embryonic limb morphogenesis+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0030917///midbrain-hindbrain boundary development+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0035108///limb morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035261///external genitalia morphogenesis+++GO:0036342///post-anal tail morphogenesis+++GO:0042074///cell migration involved in gastrulation+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045778///positive regulation of ossification+++GO:0045780///positive regulation of bone resorption+++GO:0045787///positive regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046849///bone remodeling+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048699///generation of neurons+++GO:0048705///skeletal system morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051593///response to folic acid+++GO:0060021///roof of mouth development+++GO:0060026///convergent extension+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060070///canonical Wnt signaling pathway+++GO:0060284///regulation of cell development+++GO:0060325///face morphogenesis+++GO:0060349///bone morphogenesis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060535///trachea cartilage morphogenesis+++GO:0060596///mammary placode formation+++GO:0060603///mammary gland duct morphogenesis+++GO:0061310///canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development+++GO:0061324///canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation+++GO:0071397///cellular response to cholesterol+++GO:0071542///dopaminergic neuron differentiation+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0072659///protein localization to plasma membrane+++GO:0090009///primitive streak formation+++GO:0090118///receptor-mediated endocytosis involved in cholesterol transport+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0090245///axis elongation involved in somitogenesis+++GO:0098609///cell-cell adhesion+++GO:1901998///toxin transport+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway+++GO:2000149///negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis+++GO:2000151///negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis+++GO:2000162///negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis+++GO:2000164///negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis+++GO:2000166///negative regulation of planar cell polarity pathway involved in pericardium morphogenesis+++GO:2000168///negative regulation of planar cell polarity pathway involved in neural tube closure" 16975 16975 'Lrp8' mRNA 292 314 273 2.01 2.1 1.96 0.78 0.67 0.79 2.023333333 0.746666667 129 112 133 293 124.6666667 7.63E-13 -1.243482797 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005875///microtubule associated complex+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex GO:0001540///amyloid-beta binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0019894///kinesin binding+++GO:0030229///very-low-density lipoprotein particle receptor activity+++GO:0034185///apolipoprotein binding+++GO:0038025///reelin receptor activity+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding GO:0006897///endocytosis+++GO:0007268///chemical synaptic transmission+++GO:0021517///ventral spinal cord development+++GO:0021541///ammon gyrus development+++GO:0021766///hippocampus development+++GO:0021819///layer formation in cerebral cortex+++GO:0021987///cerebral cortex development+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0038026///reelin-mediated signaling pathway+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0045088///regulation of innate immune response+++GO:0045860///positive regulation of protein kinase activity+++GO:0048813///dendrite morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0071363///cellular response to growth factor stimulus+++GO:0071397///cellular response to cholesterol+++GO:1900006///positive regulation of dendrite development 16976 16976 'Lrpap1' mRNA 7680 8150 8203 144.49 150.9 163.71 175.6 178.61 169.18 153.0333333 174.4633333 10739 10668 10018 8011 10475 5.09E-09 0.373335388 04979///Cholesterol metabolism GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0005801///cis-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0031904///endosome lumen+++GO:0031982///vesicle+++GO:0048237///rough endoplasmic reticulum lumen GO:0008201///heparin binding+++GO:0035473///lipase binding+++GO:0048018///receptor ligand activity+++GO:0048019///receptor antagonist activity+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0070326///very-low-density lipoprotein particle receptor binding GO:0002091///negative regulation of receptor internalization+++GO:0007165///signal transduction+++GO:0010916///negative regulation of very-low-density lipoprotein particle clearance+++GO:0032091///negative regulation of protein binding+++GO:0048259///regulation of receptor-mediated endocytosis+++GO:0060548///negative regulation of cell death+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:2000272///negative regulation of signaling receptor activity 16977 16977 'Lrrc23' mRNA 206 189 199 8.17 7.34 8.29 1.43 1.31 1.2 7.933333333 1.313333333 44 38 37 198 39.66666667 5.84E-22 -2.333364482 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 16978 16978 'Lrrfip1' mRNA 1299 1239 1234 19.89 18.51 20.08 26.56 26.37 24.64 19.49333333 25.85666667 1933 1901 1755 1257.333333 1863 1.73E-12 0.5550817 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity" 16979 16979 'Lrrn1' mRNA 2512 2604 2587 36.22 36.94 39.57 6.58 6.58 6.8 37.57666667 6.653333333 525 513 526 2567.666667 521.3333333 6.17E-178 -2.313088252 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0051965///positive regulation of synapse assembly 16980 16980 'Lrrn2' mRNA 135 124 111 2.2 1.99 1.92 1.37 1.73 1.37 2.036666667 1.49 97 119 94 123.3333333 103.3333333 0.341299603 -0.263260882 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function 16981 16981 'Lrrn3' mRNA 275 295 299 4.28 4.52 4.94 4.55 5.49 4.57 4.58 4.87 336 396 327 289.6666667 353 0.102456477 0.273373805 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030131///clathrin adaptor complex+++GO:0031012///extracellular matrix GO:0044877///protein-containing complex binding GO:0001934///positive regulation of protein phosphorylation+++GO:0051965///positive regulation of synapse assembly 16985 16985 'Lsp1' mRNA 53 69 65 2.31 2.88 2.83 52.29 54.07 51.45 2.673333333 52.60333333 1397 1422 1342 62.33333333 1387 1.39E-216 4.464629347 04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003779///actin binding GO:0006915///apoptotic process+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0098761///cellular response to interleukin-7 16987 16987 'Lss' mRNA 982 1047 919 8.85 10.21 10.27 5.26 5.2 5.18 9.776666667 5.213333333 491 561 516 982.6666667 522.6666667 2.83E-19 -0.919809806 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000250///lanosterol synthase activity+++GO:0016853///isomerase activity+++GO:0016866///intramolecular transferase activity+++GO:0042300///beta-amyrin synthase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0016104///triterpenoid biosynthetic process+++GO:0016125///sterol metabolic process+++GO:0031647///regulation of protein stability 16988 16988 'Lst1' mRNA 65 65 74 15.22 15.32 18.41 98.54 118.06 114.1 16.31666667 110.2333333 476 552 529 68 519 5.76E-63 2.920305613 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0000902///cell morphogenesis+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0008360///regulation of cell shape+++GO:0016358///dendrite development+++GO:0050672///negative regulation of lymphocyte proliferation 16992 16992 'Lta' mRNA 5 9 4 0.22 0.38 0.18 0.53 0.5 0.78 0.26 0.603333333 14 13 20 6 15.66666667 0.096535398 1.382955241 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04064///NF-kappa B signaling pathway+++04668///TNF signaling pathway+++04940///Type I diabetes mellitus+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding GO:0001666///response to hypoxia+++GO:0002876///positive regulation of chronic inflammatory response to antigenic stimulus+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007584///response to nutrient+++GO:0008284///positive regulation of cell proliferation+++GO:0009987///cellular process+++GO:0032496///response to lipopolysaccharide+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048535///lymph node development+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060252///positive regulation of glial cell proliferation 16993 16993 'Lta4h' mRNA 1333 1399 1251 36.91 38.04 36.72 43.61 45.41 44.95 37.22333333 44.65666667 1818 1846 1811 1327.666667 1825 1.29E-09 0.448857079 00590///Arachidonic acid metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0004301///epoxide hydrolase activity+++GO:0004463///leukotriene-A4 hydrolase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0045148///tripeptide aminopeptidase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0006691///leukotriene metabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0043171///peptide catabolic process+++GO:0044267///cellular protein metabolic process 16994 16994 'Ltb' mRNA 9 14 14 0.51 0.79 0.85 2.69 2.61 1.5 0.716666667 2.266666667 54 51 29 12.33333333 44.66666667 3.61E-04 1.840781656 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++05323///Rheumatoid arthritis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010467///gene expression+++GO:0032735///positive regulation of interleukin-12 production+++GO:0043588///skin development+++GO:0048535///lymph node development 16995 16995 'Ltb4r1' mRNA 8 7 6 0.34 0.3 0.27 4.75 4.75 4.1 0.303333333 4.533333333 127 124 106 7 119 8.34E-22 4.077211694 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0001632///leukotriene B4 receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004974///leukotriene receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0061737///leukotriene signaling pathway 16997 16997 'Ltbp2' mRNA 270 252 238 2.17 1.97 2.02 2.72 2.3 1.96 2.053333333 2.326666667 391 330 272 253.3333333 331 0.033179374 0.373156752 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding+++GO:0050436///microfibril binding GO:0097435///supramolecular fiber organization 16998 16998 'Ltbp3' mRNA 2459 2519 2551 29.29 29.77 32.58 26.65 26.16 26.26 30.54666667 26.35666667 2551.42 2463.34 2458 2509.666667 2490.92 0.808303839 -0.024298906 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding+++GO:0050431///transforming growth factor beta binding+++GO:0050436///microfibril binding GO:0001501///skeletal system development+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0030502///negative regulation of bone mineralization+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0036363///transforming growth factor beta activation+++GO:0045780///positive regulation of bone resorption+++GO:0046849///bone remodeling+++GO:0048251///elastic fiber assembly+++GO:0060349///bone morphogenesis+++GO:0060430///lung saccule development+++GO:0097435///supramolecular fiber organization+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:2000741///positive regulation of mesenchymal stem cell differentiation 17000 17000 'Ltbr' mRNA 1414 1475 1009 37.96 38.95 28.69 58.05 59.12 61.37 35.2 59.51333333 2489 2474 2544 1299.333333 2502.333333 1.86E-22 0.941309591 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04672///Intestinal immune network for IgA production+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade+++GO:0048534///hematopoietic or lymphoid organ development+++GO:0048535///lymph node development+++GO:0071260///cellular response to mechanical stimulus+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 17001 17001 'Ltc4s' mRNA 28 33 17 3.09 3.62 1.98 35.89 39.66 32.1 2.896666667 35.88333333 369 396 317 26 360.6666667 2.94E-55 3.788251227 00590///Arachidonic acid metabolism GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004364///glutathione transferase activity+++GO:0004464///leukotriene-C4 synthase activity+++GO:0004602///glutathione peroxidase activity+++GO:0008047///enzyme activator activity+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0043295///glutathione binding+++GO:0044877///protein-containing complex binding GO:0006629///lipid metabolic process+++GO:0006691///leukotriene metabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0098869///cellular oxidant detoxification 17002 17002 'Ltf' mRNA 25 35 35 0.5 0.69 0.75 2.79 3.25 2.86 0.646666667 2.966666667 159 181 158 31.66666667 166 4.82E-18 2.377939487 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0042581///specific granule+++GO:0055037///recycling endosome GO:0001530///lipopolysaccharide binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005506///iron ion binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0001817///regulation of cytokine production+++GO:0002227///innate immune response in mucosa+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0031640///killing of cells of other organism+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032780///negative regulation of ATPase activity+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044793///negative regulation by host of viral process+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045837///negative regulation of membrane potential+++GO:0048525///negative regulation of viral process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051673///membrane disruption in other organism+++GO:0055072///iron ion homeostasis+++GO:0060349///bone morphogenesis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1900159///positive regulation of bone mineralization involved in bone maturation+++GO:1900229///negative regulation of single-species biofilm formation in or on host organism+++GO:1902732///positive regulation of chondrocyte proliferation+++GO:2000117///negative regulation of cysteine-type endopeptidase activity+++GO:2000308///negative regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:2001205///negative regulation of osteoclast development 17005 17005 'Ltk' mRNA 61 66 76 1.51 1.61 2 0.77 0.83 0.75 1.706666667 0.783333333 35 37 33 67.66666667 35 0.007082263 -0.966970889 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0071300///cellular response to retinoic acid 17022 17022 'Lum' mRNA 1021 1054 1046 27.9 28.38 30.33 99.43 96.93 95.95 28.87 97.43666667 4183 3981 3907 1040.333333 4023.666667 3.67E-179 1.938711818 05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005583///fibrillar collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance GO:0007601///visual perception+++GO:0014070///response to organic cyclic compound+++GO:0030199///collagen fibril organization+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development+++GO:0070848///response to growth factor 17025 17025 'Alad' mRNA 4802 4844 4615 180.56 178.71 189.89 139.48 143.99 142.56 183.0533333 142.01 4043 4097 4009 4753.666667 4049.666667 3.61E-05 -0.24255434 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005615///extracellular space+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004655///porphobilinogen synthase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1904854///proteasome core complex binding GO:0001666///response to hypoxia+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0007584///response to nutrient+++GO:0008152///metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0009635///response to herbicide+++GO:0009636///response to toxic substance+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0010038///response to metal ion+++GO:0010039///response to iron ion+++GO:0010043///response to zinc ion+++GO:0010044///response to aluminum ion+++GO:0010212///response to ionizing radiation+++GO:0010266///response to vitamin B1+++GO:0010269///response to selenium ion+++GO:0010288///response to lead ion+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0031667///response to nutrient levels+++GO:0032025///response to cobalt ion+++GO:0032496///response to lipopolysaccharide+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0033197///response to vitamin E+++GO:0033273///response to vitamin+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0045471///response to ethanol+++GO:0046685///response to arsenic-containing substance+++GO:0046686///response to cadmium ion+++GO:0046689///response to mercury ion+++GO:0051260///protein homooligomerization+++GO:0051384///response to glucocorticoid+++GO:0051597///response to methylmercury+++GO:0070541///response to platinum ion+++GO:0070542///response to fatty acid+++GO:0071284///cellular response to lead ion+++GO:0071353///cellular response to interleukin-4+++GO:1901799///negative regulation of proteasomal protein catabolic process 17035 17035 'Lxn' mRNA 108 125 105 6.19 7.09 6.39 28.45 29.29 31.04 6.556666667 29.59333333 569 571 600 112.6666667 580 2.26E-58 2.354232551 GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004857///enzyme inhibitor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008201///heparin binding+++GO:0030414///peptidase inhibitor activity GO:0006954///inflammatory response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain 170439 170439 'Elovl6' mRNA 1000 999 873 8.92 8.76 8.26 5.27 4.58 4.82 8.646666667 4.89 680 578 603 957.3333333 620.3333333 9.60E-11 -0.636747597 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0009923///fatty acid elongase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity" "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0120162///positive regulation of cold-induced thermogenesis" 170441 170441 'Slc2a10' mRNA 892 862 854 14.14 13.45 14.36 8.25 8.8 9.03 13.98333333 8.693333333 599 624 635 869.3333333 619.3333333 6.77E-07 -0.500686386 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032683///negative regulation of connective tissue growth factor production+++GO:0043588///skin development+++GO:0045454///cell redox homeostasis+++GO:0055085///transmembrane transport+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0060840///artery development+++GO:0070837///dehydroascorbic acid transport+++GO:0072498///embryonic skeletal joint development+++GO:0098708///glucose import across plasma membrane+++GO:1902729///negative regulation of proteoglycan biosynthetic process+++GO:1902730///positive regulation of proteoglycan biosynthetic process+++GO:1903053///regulation of extracellular matrix organization+++GO:1904659///glucose transmembrane transport+++GO:2001045///negative regulation of integrin-mediated signaling pathway 170442 170442 'Bbox1' mRNA 220 187 187 6.1 5.12 4.98 0.56 0.38 0.39 5.4 0.443333333 22 13 15 198 16.66666667 1.55E-32 -3.583701836 00310///Lysine degradation GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0005506///iron ion binding+++GO:0008270///zinc ion binding+++GO:0008336///gamma-butyrobetaine dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0045329///carnitine biosynthetic process 170458 170458 'Gpha2' mRNA 3 9 3 0.39 1.18 0.42 0.12 0.12 0.72 0.663333333 0.32 1 1 6 5 2.666666667 0.593128933 -0.899187807 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031531///thyrotropin-releasing hormone receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0051427///hormone receptor binding GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 170459 170459 'Stard4' mRNA 352 362 257 3.53 3.57 2.74 2.18 1.96 2.22 3.28 2.12 250 220 247 323.6666667 239 0.008716334 -0.443780356 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006869///lipid transport+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010879///cholesterol transport involved in cholesterol storage+++GO:0032367///intracellular cholesterol transport+++GO:0034435///cholesterol esterification+++GO:0070508///cholesterol import+++GO:0070859///positive regulation of bile acid biosynthetic process+++GO:0120009///intermembrane lipid transfer 170460 170460 'Stard5' mRNA 952 997 890 21.93 22.61 21.75 26.52 27.08 29.01 22.09666667 27.53666667 1324 1320 1402 946.3333333 1348.666667 2.30E-09 0.501001594 GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0032052///bile acid binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0070508///cholesterol import+++GO:0120009///intermembrane lipid transfer 170461 170461 'Stard6' mRNA 35 30 29 1.33 1.04 1.22 1.31 1.45 1.44 1.196666667 1.4 38 41 44 31.33333333 41 0.429617446 0.378330625 GO:0008289///lipid binding+++GO:0015485///cholesterol binding GO:0006869///lipid transport+++GO:0008150///biological_process 170472 170472 'Recql5' mRNA 565 500 541 9.23 7.91 9.87 6.79 6.48 6.22 9.003333333 6.496666667 485 459 475 535.3333333 473 0.151681336 -0.192042635 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016591///RNA polymerase II, holoenzyme" GO:0000166///nucleotide binding+++GO:0000993///RNA polymerase II complex binding+++GO:0003676///nucleic acid binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043138///3'-5' DNA helicase activity GO:0000278///mitotic cell cycle+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0035690///cellular response to drug+++GO:0051301///cell division+++GO:0051304///chromosome separation+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0072757///cellular response to camptothecin+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 170483 170483 'Grin3b' mRNA 34 17 22 0.54 0.3 0.41 0.37 0.29 0.27 0.416666667 0.31 25 19 21 24.33333333 21.66666667 0.804603501 -0.180838348 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0016594///glycine binding+++GO:0030594///neurotransmitter receptor activity+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0051205///protein insertion into membrane+++GO:0051924///regulation of calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 170484 170484 'Nphs2' mRNA 0 4 0 0 0.08 0 0.1 0.15 0.05 0.026666667 0.1 4 6 3 1.333333333 4.333333333 0.374343248 1.724038441 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0045121///membrane raft GO:0005515///protein binding GO:0031532///actin cytoskeleton reorganization+++GO:0072249///metanephric glomerular visceral epithelial cell development 17057 17057 'Klrb1a' mRNA 115 124 81 5.52 5.89 4.1 2.95 3.24 3.24 5.17 3.143333333 70.94 76 75 106.6666667 73.98 0.061017107 -0.537680463 05144///Malaria GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0008150///biological_process 170571 170571 'Cntnap4' mRNA 622 728 687 6.8 7.87 8 3.56 3.95 3.98 7.556666667 3.83 374 408 405 679 395.6666667 8.03E-11 -0.790751802 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding "GO:0007155///cell adhesion+++GO:0032225///regulation of synaptic transmission, dopaminergic+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0050807///regulation of synapse organization+++GO:2000821///regulation of grooming behavior" 170574 170574 'Sp7' mRNA 42 61 59 0.77 1.08 1.12 1.23 1.06 1.4 0.99 1.23 77 66 86 54 76.33333333 0.168171232 0.484611805 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0046872///metal ion binding" GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060218///hematopoietic stem cell differentiation+++GO:2000738///positive regulation of stem cell differentiation 17059 17059 'Klrb1c' mRNA 6 10.66 6 0.13 0.22 0.13 0.22 0.31 0.42 0.16 0.316666667 12.06 16.72 21.94 7.553333333 16.90666667 0.149624195 1.15221858 05144///Malaria GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0030101///natural killer cell activation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 17060 17060 'Blnk' mRNA 218 241 219 7.06 7.69 7.52 26.81 27.75 22.9 7.423333333 25.82 952 962 787 226 900.3333333 7.75E-57 1.982961286 04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway+++05169///Epstein-Barr virus infection+++05340///Primary immunodeficiency GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0035591///signaling adaptor activity+++GO:0042169///SH2 domain binding+++GO:0043274///phospholipase binding+++GO:1990782///protein tyrosine kinase binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0035556///intracellular signal transduction+++GO:0042113///B cell activation+++GO:0050853///B cell receptor signaling pathway 170625 170625 'Snx18' mRNA 765 874 283 9.24 10.38 3.62 4.43 6.83 6.79 7.746666667 6.016666667 422 636 627 640.6666667 561.6666667 0.804427428 -0.174780422 05132///Salmonella infection GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030426///growth cone+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome "GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding" GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0006897///endocytosis+++GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0036089///cleavage furrow formation+++GO:0043547///positive regulation of GTPase activity+++GO:0051301///cell division 17063 17063 'Muc13' mRNA 0 1 0 0 0.02 0 0.02 0.07 0.02 0.006666667 0.036666667 1 4 1 0.333333333 2 0.386106785 2.480518094 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0042803///protein homodimerization activity GO:0030277///maintenance of gastrointestinal epithelium 170638 170638 'Hpcal4' mRNA 43 76 75 0.5 0.86 0.92 0.37 0.39 0.57 0.76 0.443333333 37 38 55 64.66666667 43.33333333 0.149434022 -0.592817754 GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0008150///biological_process 170639 170639 'Olfr78' mRNA 1 10 4 0.02 0.17 0.07 0.04 0.02 0.08 0.086666667 0.046666667 2 1 4 5 2.333333333 0.51032349 -1.101061937 04740///Olfactory transduction GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0043229///intracellular organelle GO:0003707///steroid hormone receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0038023///signaling receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0016477///cell migration+++GO:0030318///melanocyte differentiation+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045777///positive regulation of blood pressure+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0071398///cellular response to fatty acid+++GO:0097325///melanocyte proliferation+++GO:1900135///positive regulation of renin secretion into blood stream 17064 17064 'Cd93' mRNA 127 128.38 121.06 1.01 1.01 1.02 10.28 8.6 9.04 1.013333333 9.306666667 1486.16 1214.53 1265.99 125.48 1322.226667 2.87E-165 3.385685186 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0001849///complement component C1q binding+++GO:0005509///calcium ion binding+++GO:0030246///carbohydrate binding GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 170643 170643 'Kirrel' mRNA 711.54 765.58 541.7 3.15 3.47 2.15 3.86 3.02 4.22 2.923333333 3.7 989.24 747.01 966.01 672.94 900.7533333 0.00157362 0.414348838 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031253///cell projection membrane+++GO:0043198///dendritic shaft+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0050839///cell adhesion molecule binding GO:0001933///negative regulation of protein phosphorylation+++GO:0007588///excretion+++GO:0030838///positive regulation of actin filament polymerization+++GO:0098609///cell-cell adhesion 170644 170644 'Ubn1' mRNA 711 732 636 6.2 6.27 6.03 5.6 5.68 5.44 6.166666667 5.573333333 733 721 681 693 711.6666667 0.848903825 0.028524866 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005923///bicellular tight junction+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030054///cell junction+++GO:0034451///centriolar satellite GO:0003677///DNA binding+++GO:0008134///transcription factor binding GO:0006325///chromatin organization+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0030216///keratinocyte differentiation 17067 17067 'Ly6c1' mRNA 1109.23 1109.37 1116.46 86.93 85.45 92.55 151 136.53 147.56 88.31 145.03 2216.86 1959.33 2096.56 1111.686667 2090.916667 4.98E-31 0.897947616 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 170676 170676 'Peg10' mRNA 32 28 24 0.25 0.22 0.2 0.27 0.15 0.22 0.223333333 0.213333333 39 21 31 28 30.33333333 0.863090843 0.102688309 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0001890///placenta development+++GO:0006915///apoptotic process+++GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway 170677 170677 'Cdhr1' mRNA 31 22 38 0.38 0.27 0.5 0.3 0.23 0.28 0.383333333 0.27 28 21 25 30.33333333 24.66666667 0.596918197 -0.321467185 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042622///photoreceptor outer segment membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0008594///photoreceptor cell morphogenesis+++GO:0009987///cellular process+++GO:0035845///photoreceptor cell outer segment organization+++GO:0045494///photoreceptor cell maintenance 17068 17068 'Ly6d' mRNA 0 2 1 0 0.21 0.11 0.64 1.12 1.04 0.106666667 0.933333333 7 12 11 1 10 0.014685675 3.317959558 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0030098///lymphocyte differentiation+++GO:0035634///response to stilbenoid 17069 17069 'Ly6e' mRNA 24063 23981 23331 652.38 639.89 671.64 1566.06 1560.54 1529.09 654.6366667 1551.896667 65957 64100 62366 23791.66667 64141 2.25E-203 1.418524289 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0001701///in utero embryonic development+++GO:0030325///adrenal gland development+++GO:0035265///organ growth+++GO:0042415///norepinephrine metabolic process+++GO:0046597///negative regulation of viral entry into host cell+++GO:0048242///epinephrine secretion+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 170706 170706 'Tmem37' mRNA 1943 2046 1923 121.65 126.66 127.75 214.37 213.2 192.15 125.3533333 206.5733333 3926 3806 3401 1970.666667 3711 1.89E-37 0.901150266 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005262///calcium channel activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport 170707 170707 'Usp48' mRNA 1976.42 1956.55 1858.04 18.12 17.66 18.21 12.55 12.33 13.09 17.99666667 12.65666667 1583.64 1511.81 1591.68 1930.336667 1562.376667 1.13E-05 -0.316988935 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 170711 170711 'Otud7a' mRNA 62.17 74.69 51.14 0.24 0.22 0.14 0.18 0.21 0.2 0.2 0.196666667 54.97 53.57 49.66 62.66666667 52.73333333 0.498709622 -0.267879524 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006508///proteolysis+++GO:0035871///protein K11-linked deubiquitination+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process 170716 170716 'Cyp4f13' mRNA 476 460 485 16.23 15.66 18.12 16.34 15.56 15.03 16.67 15.64333333 527 504 485 473.6666667 505.3333333 0.605754405 0.079757987 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006691///leukotriene metabolic process 170718 170718 'Idh3b' mRNA 3817 3935 3571 148.24 151.16 147.38 122.39 120.15 121.82 148.9266667 121.4533333 3613 3460 3479 3774.333333 3517.333333 0.068768221 -0.112587281 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion "GO:0000287///magnesium ion binding+++GO:0004449///isocitrate dehydrogenase (NAD+) activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0051287///NAD binding" GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006734///NADH metabolic process 170719 170719 'Oxr1' mRNA 3066 3101 2687 36.97 37.55 35.45 18.36 17.63 17.42 36.65666667 17.80333333 1407 1330 1345 2951.333333 1360.666667 1.56E-64 -1.126773404 GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion GO:0016491///oxidoreductase activity "GO:0002376///immune system process+++GO:0006955///immune response+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0006979///response to oxidative stress+++GO:0007628///adult walking behavior+++GO:0019835///cytolysis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0051402///neuron apoptotic process+++GO:0071447///cellular response to hydroperoxide+++GO:1900408///negative regulation of cellular response to oxidative stress+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1903204///negative regulation of oxidative stress-induced neuron death" 170720 170720 'Card14' mRNA 16.2 1.07 10.87 0.21 0.01 0.15 0.48 0.3 0.33 0.123333333 0.37 41.82 26.91 28.78 9.38 32.50333333 0.010938007 1.791260063 04064///NF-kappa B signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome GO:0050700///CARD domain binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 170721 170721 'Papln' mRNA 49.73 59.55 26.06 0.45 0.51 0.2 0.5 0.21 0.22 0.386666667 0.31 62.1 32.58 33.31 45.11333333 42.66333333 0.882290806 -0.081696931 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005201///extracellular matrix structural constituent+++GO:0030414///peptidase inhibitor activity GO:0006508///proteolysis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030198///extracellular matrix organization 170722 170722 'Nxf7' mRNA 143 179 158 3.65 4.49 4.27 1.93 1.43 1.22 4.136666667 1.526666667 87 63 53 160 67.66666667 7.97E-07 -1.255948149 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006406///mRNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 170725 170725 'Capn8' mRNA 3 1 6 0.06 0.02 0.14 0 0 0.05 0.073333333 0.016666667 0 0 4 3.333333333 1.333333333 0.547400585 -1.358357383 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007586///digestion+++GO:1990092///calcium-dependent self proteolysis 170728 170728 'Rtn4ip1' mRNA 329 409 387 6.07 7.42 7.57 7.92 7.81 7.26 7.02 7.663333333 494 476 438 375 469.3333333 0.033013374 0.310499813 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity GO:0007399///nervous system development+++GO:0050773///regulation of dendrite development 170729 170729 'Scrt1' mRNA 7 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 2.333333333 0 0.294225106 -3.649876527 GO:0005634///nucleus+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:2001222///regulation of neuron migration" 170731 170731 'Mfn2' mRNA 1726 1823 1839 20.63 21.41 23.39 19.76 17.89 18.67 21.81 18.77333333 1903 1683 1736 1796 1774 0.773395844 -0.032080126 04137///Mitophagy - animal+++04214///Apoptosis - fly+++04621///NOD-like receptor signaling pathway+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031306///intrinsic component of mitochondrial outer membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043394///proteoglycan binding+++GO:0051020///GTPase binding GO:0001825///blastocyst formation+++GO:0006626///protein targeting to mitochondrion+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0007005///mitochondrion organization+++GO:0007006///mitochondrial membrane organization+++GO:0007275///multicellular organism development+++GO:0008053///mitochondrial fusion+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010729///positive regulation of hydrogen peroxide biosynthetic process+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0034497///protein localization to phagophore assembly site+++GO:0035563///positive regulation of chromatin binding+++GO:0045786///negative regulation of cell cycle+++GO:0045792///negative regulation of cell size+++GO:0046326///positive regulation of glucose import+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0048312///intracellular distribution of mitochondria+++GO:0048593///camera-type eye morphogenesis+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051646///mitochondrion localization+++GO:0051726///regulation of cell cycle+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060299///negative regulation of sarcomere organization+++GO:0060548///negative regulation of cell death+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0070584///mitochondrion morphogenesis+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090258///negative regulation of mitochondrial fission+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901215///negative regulation of neuron death+++GO:1901857///positive regulation of cellular respiration+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:2000386///positive regulation of ovarian follicle development+++GO:2000866///positive regulation of estradiol secretion+++GO:2000872///positive regulation of progesterone secretion 170732 170732 'Trhr2' mRNA 0 1 1 0 0.03 0.03 0.02 0 0 0.02 0.006666667 1 0 0 0.666666667 0.333333333 0.861917436 -0.920429697 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0004930///G protein-coupled receptor activity+++GO:0004997///thyrotropin-releasing hormone receptor activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway 170733 170733 'Klra17' mRNA 2 0 0 0.1 0 0 1.45 0.37 1.16 0.033333333 0.993333333 32 8 25 0.666666667 21.66666667 1.81E-04 5.007587306 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding+++GO:0042288///MHC class I protein binding 170734 170734 'Zscan5b' mRNA 1 0 1 0.03 0 0.04 0.03 0 0 0.023333333 0.01 1 0 0 0.666666667 0.333333333 0.860258084 -0.929065017 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 170735 170735 'Arr3' mRNA 0 2 1 0 0.07 0.04 0.04 0.04 0.04 0.036666667 0.04 1 1 1 1 1 0.998591786 -0.006932134 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0042995///cell projection+++GO:0045202///synapse GO:0001664///G protein-coupled receptor binding+++GO:0002046///opsin binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0051219///phosphoprotein binding GO:0001932///regulation of protein phosphorylation+++GO:0002031///G protein-coupled receptor internalization+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0050896///response to stimulus 170736 170736 'Parvb' mRNA 145 138 85 2.12 1.98 1.32 4.72 4.44 4.15 1.806666667 4.436666667 372 343 317 122.6666667 344 3.79E-15 1.483213259 04510///Focal adhesion GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0031532///actin cytoskeleton reorganization+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0071963///establishment or maintenance of cell polarity regulating cell shape 170737 170737 'Znrf1' mRNA 460 431 357 5.46 4.85 4.79 4.47 4.34 5.26 5.033333333 4.69 408 409 483 416 433.3333333 0.787259291 0.051419808 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007010///cytoskeleton organization+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 170738 170738 'Kcnh7' mRNA 1594.24 1615.95 1387.55 7.13 7.25 5.81 0.9 0.76 0.83 6.73 0.83 381.72 311.53 338.55 1532.58 343.9333333 1.01E-110 -2.168198091 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0086011///membrane repolarization during action potential 170740 170740 'Zfp287' mRNA 348.6 377.2 378.83 5.56 5.56 6.73 4.88 4.66 4.66 5.95 4.733333333 280.49 252.13 255.96 368.21 262.86 7.65E-04 -0.500894901 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0001817///regulation of cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 170741 170741 'Pilrb1' mRNA 4.33 4 4 0.22 0.25 0.26 3.66 2.34 3.82 0.243333333 3.273333333 70.75 44.64 72 4.11 62.46333333 1.87E-11 3.939948219 05168///Herpes simplex virus 1 infection GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0042288///MHC class I protein binding GO:0001773///myeloid dendritic cell activation+++GO:0045671///negative regulation of osteoclast differentiation 170742 170742 'Sertad3' mRNA 400 481 395 19.37 23 20.3 23.84 22.67 23.73 20.89 23.41333333 565 524 544 425.3333333 544.3333333 0.006285434 0.34580628 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated" 170743 170743 'Tlr7' mRNA 417.68 373.2 258.51 4.08 3.6 2.69 8.98 8.02 8.27 3.456666667 8.423333333 955.27 797.71 843.76 349.7966667 865.58 1.48E-21 1.302182394 04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++05162///Measles+++05164///Influenza A+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0043235///receptor complex+++GO:0045335///phagocytic vesicle GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0035197///siRNA binding+++GO:0038187///pattern recognition receptor activity GO:0000165///MAPK cascade+++GO:0001932///regulation of protein phosphorylation+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007252///I-kappaB phosphorylation+++GO:0007254///JNK cascade+++GO:0032722///positive regulation of chemokine production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0071260///cellular response to mechanical stimulus+++GO:0098586///cellular response to virus+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 170744 170744 'Tlr8' mRNA 34 43 38 0.37 0.49 0.48 5.16 4.9 4.57 0.446666667 4.876666667 534 493 450 38.33333333 492.3333333 2.03E-77 3.671156558 04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++05171///Coronavirus disease - COVID-19 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding GO:0001817///regulation of cytokine production+++GO:0001932///regulation of protein phosphorylation+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034158///toll-like receptor 8 signaling pathway+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus+++GO:0071260///cellular response to mechanical stimulus 170745 170745 'Xpnpep2' mRNA 14.17 13.25 13 0.24 0.22 0.23 0.09 0.16 0.09 0.23 0.113333333 6.01 10.99 6.02 13.47333333 7.673333333 0.317756176 -0.871013801 04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0070062///extracellular exosome GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0008150///biological_process 170748 170748 'Smco4' mRNA 13 4 6 0.88 0.25 0.41 0.62 0.69 0.8 0.513333333 0.703333333 11 12 13 7.666666667 12 0.516370406 0.638422606 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 170749 170749 'Mtmr4' mRNA 1180 1125 1072 9.99 9.45 9.87 7.01 7.42 7.39 9.77 7.273333333 932 957 939 1125.666667 942.6666667 0.003146819 -0.266661072 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04140///Autophagy - animal GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019903///protein phosphatase binding+++GO:0046872///metal ion binding+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity" GO:0006470///protein dephosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010506///regulation of autophagy+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0060304///regulation of phosphatidylinositol dephosphorylation 17075 17075 'Epcam' mRNA 13436 13598 13277 369.97 368.84 387.83 369.44 367.7 376.49 375.5466667 371.21 15426 14989 15216 13437 15210.33333 0.001488713 0.166463061 GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction GO:0044877///protein-containing complex binding+++GO:0098641///cadherin binding involved in cell-cell adhesion GO:0001657///ureteric bud development+++GO:0008284///positive regulation of cell proliferation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000147///positive regulation of cell motility+++GO:2000648///positive regulation of stem cell proliferation 170750 170750 'Xpnpep1' mRNA 4402.86 4479.91 4443.41 99.57 99.52 106.49 202.82 203.5 203.57 101.86 203.2966667 9941.52 9749.06 9704.28 4442.06 9798.286667 8.76E-94 1.128841893 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0010815///bradykinin catabolic process 170752 170752 'Bco2' mRNA 11 22 18 0.29 0.61 0.53 1.27 1.15 1.18 0.476666667 1.2 55 51 49 17 51.66666667 4.14E-04 1.591038386 GO:0005739///mitochondrion "GO:0003834///beta-carotene 15,15'-monooxygenase activity+++GO:0010436///carotenoid dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0102076///beta,beta-carotene-9',10'-cleaving oxygenase activity" GO:0016116///carotenoid metabolic process+++GO:0016119///carotene metabolic process+++GO:0016121///carotene catabolic process+++GO:0016122///xanthophyll metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042574///retinal metabolic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:2000377///regulation of reactive oxygen species metabolic process 170753 170753 'Zfp704' mRNA 852 805 752 3.34 3.11 3.13 2.12 1.73 2.06 3.193333333 1.97 621 496 582.99 803 566.6633333 2.88E-06 -0.51584333 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 170755 170755 'Sgk3' mRNA 637.89 609.21 633.48 6.22 5.85 6.56 7.75 6.95 7.62 6.21 7.44 918.02 805.01 875.19 626.86 866.0733333 1.24E-05 0.453654403 04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0015459///potassium channel regulator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035091///phosphatidylinositol binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 170756 170756 'Slc8b1' mRNA 762.54 756.54 714.45 14.9 14.55 14.88 17.89 19.86 18.75 14.77666667 18.83333333 1037.89 1132.76 1062.49 744.51 1077.713333 2.95E-08 0.523373571 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0032592///integral component of mitochondrial membrane+++GO:0042383///sarcolemma GO:0005432///calcium:sodium antiporter activity+++GO:0008324///cation transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0086038///calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0035725///sodium ion transmembrane transport+++GO:0042593///glucose homeostasis+++GO:0050796///regulation of insulin secretion+++GO:0050896///response to stimulus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0099093///calcium export from the mitochondrion+++GO:1901623///regulation of lymphocyte chemotaxis+++GO:2001256///regulation of store-operated calcium entry 170757 170757 'Adgrl4' mRNA 382 318 440 5.02 4.11 6.13 9.43 8.1 8.24 5.086666667 8.59 827 694 700 380 740.3333333 5.30E-11 0.942256483 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0065003///protein-containing complex assembly 170758 170758 'Rac3' mRNA 181 169 110 10.55 9.73 6.8 12.09 10.37 12.88 9.026666667 11.78 238 199 245 153.3333333 227.3333333 0.008251047 0.563389836 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05416///Viral myocarditis+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0048306///calcium-dependent protein binding "GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0014041///regulation of neuron maturation+++GO:0016055///Wnt signaling pathway+++GO:0021894///cerebral cortex GABAergic interneuron development+++GO:0022604///regulation of cell morphogenesis+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030865///cortical cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process+++GO:0051932///synaptic transmission, GABAergic+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading" 170759 170759 'Atp13a1' mRNA 1532 1628 1701 21.08 22.06 24.93 19.34 19.14 17.99 22.69 18.82333333 1615 1563 1456 1620.333333 1544.666667 0.434030321 -0.083551416 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006812///cation transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0015031///protein transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 17076 17076 'Ly75' mRNA 528 515 409 4.06 3.89 3.34 0.73 0.66 0.73 3.763333333 0.706666667 109 97 106 484 104 3.61E-44 -2.226251243 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity GO:0006897///endocytosis 170760 170760 'Acbd3' mRNA 295 288 298 4.62 4.44 4.96 6.73 5.24 6.88 4.673333333 6.283333333 494 376 489 293.6666667 453 4.12E-05 0.610596063 05132///Salmonella infection GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0000062///fatty-acyl-CoA binding+++GO:0034237///protein kinase A regulatory subunit binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process 170761 170761 'Pdzd3' mRNA 24 13 16 0.62 0.33 0.44 0.52 0.32 0.58 0.463333333 0.473333333 23 14 25 17.66666667 20.66666667 0.788695373 0.212460594 GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0043296///apical junction complex+++GO:0045177///apical part of cell GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030251///guanylate cyclase inhibitor activity+++GO:0043495///protein membrane anchor+++GO:1990381///ubiquitin-specific protease binding GO:0006811///ion transport+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0031283///negative regulation of guanylate cyclase activity+++GO:0072659///protein localization to plasma membrane 170762 170762 'Nup155' mRNA 313 323 322 2.59 2.63 2.82 3.09 2.46 2.96 2.68 2.836666667 430 335 399 319.3333333 388 0.08773021 0.26664342 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0044611///nuclear pore inner ring GO:0017056///structural constituent of nuclear pore GO:0000972///transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006998///nuclear envelope organization+++GO:0015031///protein transport+++GO:0036228///protein localization to nuclear inner membrane+++GO:0051028///mRNA transport+++GO:0086014///atrial cardiac muscle cell action potential 170763 170763 'Zfp87' mRNA 376.63 416.3 340 7.69 8.37 7.37 6.59 6.42 6.31 7.81 6.44 371 353 344 377.6433333 356 0.582632108 -0.09329885 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 170765 170765 'Ripply3' mRNA 24.93 18.67 21.21 0.96 0.71 0.87 1.44 1.33 1.08 0.846666667 1.283333333 42.9 38.79 31.05 21.60333333 37.58 0.105067514 0.803076112 GO:0005634///nucleus GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0060037///pharyngeal system development 170767 170767 'Rfxap' mRNA 53 41 58 1.38 1.05 1.61 1.18 1.16 1.06 1.346666667 1.133333333 52 50 45 50.66666667 49 0.884469941 -0.066114393 04612///Antigen processing and presentation+++05152///Tuberculosis+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 170768 170768 'Pfkfb3' mRNA 1072 1168 991 11.84 12.64 11.59 19.41 18.9 19.71 12.02333333 19.34 2031 1918 1997 1077 1982 2.33E-31 0.87001614 00051///Fructose and mannose metabolism+++04066///HIF-1 signaling pathway+++04152///AMPK signaling pathway GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0003873///6-phosphofructo-2-kinase activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity" "GO:0006000///fructose metabolic process+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0007420///brain development+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0046835///carbohydrate phosphorylation" 170770 170770 'Bbc3' mRNA 30 29 18 1.04 0.99 0.71 2.35 2.84 2.45 0.913333333 2.546666667 76 86 76 25.66666667 79.33333333 5.82E-06 1.624307341 01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04390///Hippo signaling pathway+++05016///Huntington disease+++05162///Measles+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum GO:0005515///protein binding+++GO:0051117///ATPase binding GO:0001836///release of cytochrome c from mitochondria+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0030308///negative regulation of cell growth+++GO:0031334///positive regulation of protein complex assembly+++GO:0032464///positive regulation of protein homooligomerization+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045926///negative regulation of growth+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:0071479///cellular response to ionizing radiation+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097194///execution phase of apoptosis+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1901998///toxin transport+++GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 170771 170771 'Khdrbs2' mRNA 1608.64 1642.78 1459.31 3.08 3.42 3.17 1.64 1.44 1.61 3.223333333 1.563333333 1120.53 997.27 1073.5 1570.243333 1063.766667 3.34E-13 -0.57268456 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding+++GO:0017124///SH3 domain binding+++GO:0042169///SH2 domain binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0048024///regulation of mRNA splicing, via spliceosome" 170772 170772 'Glcci1' mRNA 444 407 469.69 4.25 3.84 4.8 2.44 1.83 2.17 4.296666667 2.146666667 293 214 251.3 440.23 252.7666667 1.62E-07 -0.817735123 GO:0005737///cytoplasm GO:0005515///protein binding 170776 170776 'Cd209c' mRNA 278.08 281.83 267.31 10.55 10.54 10.76 9.05 8.08 7.92 10.61666667 8.35 273.03 236.77 231.95 275.74 247.25 0.348776857 -0.171222057 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane GO:0001618///virus receptor activity+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0006955///immune response+++GO:0042102///positive regulation of T cell proliferation+++GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell+++GO:0097323///B cell adhesion+++GO:1903902///positive regulation of viral life cycle 170779 170779 'Cd209d' mRNA 1 0 2 0.1 0 0.16 0.34 0.21 0.09 0.086666667 0.213333333 4 3 1 1 2.666666667 0.555722717 1.371229524 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001819///positive regulation of cytokine production+++GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0042102///positive regulation of T cell proliferation+++GO:0042742///defense response to bacterium+++GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell+++GO:0097323///B cell adhesion+++GO:1903902///positive regulation of viral life cycle 170780 170780 'Cd209e' mRNA 0 0 2 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0042102///positive regulation of T cell proliferation+++GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell+++GO:0097323///B cell adhesion+++GO:1903902///positive regulation of viral life cycle 170786 170786 'Cd209a' mRNA 3 4 4 0.12 0.16 0.17 0.97 1.03 1.29 0.15 1.096666667 28 29 36 3.666666667 31 1.19E-05 3.068199763 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0097367///carbohydrate derivative binding GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0042102///positive regulation of T cell proliferation+++GO:0042129///regulation of T cell proliferation+++GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell+++GO:0097323///B cell adhesion+++GO:1903902///positive regulation of viral life cycle 170787 170787 'Hdac10' mRNA 437 449 462 10.18 10.27 11.42 7.89 7.18 7.93 10.62333333 7.666666667 392 348 380 449.3333333 373.3333333 0.042174702 -0.281338297 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0004407///histone deacetylase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0019899///enzyme binding+++GO:0033558///protein deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0047609///acetylputrescine deacetylase activity+++GO:0047611///acetylspermidine deacetylase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006476///protein deacetylation+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016236///macroautophagy+++GO:0016575///histone deacetylation+++GO:0032425///positive regulation of mismatch repair+++GO:0034983///peptidyl-lysine deacetylation+++GO:0035825///homologous recombination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0106047///polyamine deacetylation+++GO:0106048///spermidine deacetylation" 170788 170788 'Crb1' mRNA 11.14 13.02 11.28 0.06 0.07 0.07 0.05 0.06 0.04 0.066666667 0.05 10.18 13.05 8.61 11.81333333 10.61333333 0.863090843 -0.183592956 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0035003///subapical complex+++GO:0042995///cell projection+++GO:0043296///apical junction complex+++GO:0045177///apical part of cell+++GO:0097386///glial cell projection GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001974///blood vessel remodeling+++GO:0007009///plasma membrane organization+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007601///visual perception+++GO:0010001///glial cell differentiation+++GO:0010467///gene expression+++GO:0010842///retina layer formation+++GO:0034613///cellular protein localization+++GO:0035845///photoreceptor cell outer segment organization+++GO:0042462///eye photoreceptor cell development+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045494///photoreceptor cell maintenance+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060041///retina development in camera-type eye+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060060///post-embryonic retina morphogenesis in camera-type eye+++GO:0061024///membrane organization+++GO:0061159///establishment of bipolar cell polarity involved in cell morphogenesis+++GO:0071482///cellular response to light stimulus 170789 170789 'Acot8' mRNA 471.36 493.29 487.97 23.46 24.03 26.16 29.62 26.81 32.05 24.55 29.49333333 661.65 582.64 686.22 484.2066667 643.5033333 8.70E-04 0.397652262 00120///Primary bile acid biosynthesis+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix GO:0003986///acetyl-CoA hydrolase activity+++GO:0004778///succinyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0044466///glutaryl-CoA hydrolase activity+++GO:0047603///acetoacetyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0047994///hydroxymethylglutaryl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0007031///peroxisome organization+++GO:0009062///fatty acid catabolic process+++GO:0016559///peroxisome fission+++GO:0043649///dicarboxylic acid catabolic process+++GO:0045225///negative regulation of CD4 biosynthetic process 17079 17079 'Cd180' mRNA 4 4 9 0.1 0.09 0.23 2.83 2.99 2.62 0.14 2.813333333 130 134 117 5.666666667 127 5.57E-23 4.470034893 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0002224///toll-like receptor signaling pathway+++GO:0002322///B cell proliferation involved in immune response+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045087///innate immune response+++GO:0071222///cellular response to lipopolysaccharide 170790 170790 'Mlc1' mRNA 1 7 2 0.02 0.17 0.05 0.29 0.21 0.13 0.08 0.21 14 10 6 3.333333333 10 0.169108699 1.582662403 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097450///astrocyte end-foot GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032388///positive regulation of intracellular transport+++GO:0034220///ion transmembrane transport+++GO:0047484///regulation of response to osmotic stress+++GO:0071397///cellular response to cholesterol+++GO:0072584///caveolin-mediated endocytosis 170791 170791 'Rbm39' mRNA 7427 7383 7487 99.46 96.35 105.44 80.18 77.71 81.34 100.4166667 79.74333333 6858 6458 6804 7432.333333 6706.666667 0.009140537 -0.161624 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0050733///RS domain binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome" 170799 170799 'Rtkn2' mRNA 16.74 10.69 13.06 0.14 0.07 0.15 0.36 0.43 0.34 0.12 0.376666667 36.05 41.27 33.02 13.49666667 36.78 0.004583843 1.483933325 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0030097///hemopoiesis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 170812 170812 'Ahsp' mRNA 1 1 0 0.17 0.17 0 0.15 1.11 0.32 0.113333333 0.526666667 1 7 2 0.666666667 3.333333333 0.290334681 2.34465723 GO:0005737///cytoplasm GO:0030492///hemoglobin binding GO:0006457///protein folding+++GO:0030218///erythrocyte differentiation+++GO:0050821///protein stabilization 170813 170813 'Ms4a3' mRNA 23 24 20 1.45 1.5 1.34 0.28 0.11 0.06 1.43 0.15 5 2 1 22.33333333 2.666666667 2.76E-04 -3.080449052 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process+++GO:0051726///regulation of cell cycle 17082 17082 'Il1rl1' mRNA 7.42 5 6 0.08 0.05 0.07 0.1 0.19 0.07 0.066666667 0.12 10 21 6.99 6.14 12.66333333 0.290920621 1.032510372 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix "GO:0002113///interleukin-33 binding+++GO:0002114///interleukin-33 receptor activity+++GO:0003953///NAD+ nucleosidase activity+++GO:0004908///interleukin-1 receptor activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002826///negative regulation of T-helper 1 type immune response+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032722///positive regulation of chemokine production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0038172///interleukin-33-mediated signaling pathway+++GO:0043032///positive regulation of macrophage activation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050729///positive regulation of inflammatory response 170822 170822 'Usp33' mRNA 1336 1413 1344 17.72 18.32 18.85 12.71 13.59 13.18 18.29666667 13.16 1113 1156 1115 1364.333333 1128 8.48E-04 -0.285859352 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006897///endocytosis+++GO:0007411///axon guidance+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009267///cellular response to starvation+++GO:0010506///regulation of autophagy+++GO:0016477///cell migration+++GO:0016579///protein deubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0050821///protein stabilization+++GO:0051298///centrosome duplication+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination 170823 170823 'Glmn' mRNA 190 240.92 194.55 5.27 6.57 5.71 3.65 4.57 3.78 5.85 4 150 183 150 208.49 161 0.072960919 -0.377560249 05131///Shigellosis GO:0005737///cytoplasm+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex GO:0005102///signaling receptor binding+++GO:0005171///hepatocyte growth factor receptor binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0055105///ubiquitin-protein transferase inhibitor activity "GO:0001570///vasculogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001843///neural tube closure+++GO:0007166///cell surface receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032743///positive regulation of interleukin-2 production+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042130///negative regulation of T cell proliferation+++GO:0042327///positive regulation of phosphorylation+++GO:0042692///muscle cell differentiation+++GO:0072359///circulatory system development" 170826 170826 'Ppargc1b' mRNA 300 286.33 237 1.52 1.43 1.27 0.95 0.91 0.98 1.406666667 0.946666667 215 203 215.83 274.4433333 211.2766667 0.023608675 -0.387154762 04931///Insulin resistance GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016592///mediator complex GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0050682///AF-2 domain binding "GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006390///mitochondrial transcription+++GO:0007015///actin filament organization+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0034614///cellular response to reactive oxygen species+++GO:0042327///positive regulation of phosphorylation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP+++GO:0060346///bone trabecula formation+++GO:0120162///positive regulation of cold-induced thermogenesis" 170829 170829 'Tram2' mRNA 156 172 109 6.71 7.3 4.98 5.51 4.69 4.69 6.33 4.963333333 147 122 121 145.6666667 130 0.548478204 -0.169719353 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005515///protein binding "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0015031///protein transport+++GO:0032964///collagen biosynthetic process+++GO:0045048///protein insertion into ER membrane" 17083 17083 'Tmed1' mRNA 1652.95 1654.31 1716.72 63.41 62.69 70.04 64.18 64.29 64.22 65.38 64.23 1921.93 1878.42 1854.42 1674.66 1884.923333 0.062056336 0.157227647 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport 170833 170833 'Hook2' mRNA 866 975 889 16.42 17.9 17.75 12.17 11.74 13.59 17.35666667 12.5 723 678 768 910 723 8.63E-04 -0.343429388 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030897///HOPS complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070695///FHF complex GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0051959///dynein light intermediate chain binding GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0045022///early endosome to late endosome transport+++GO:1905719///protein localization to perinuclear region of cytoplasm 170835 170835 'Inpp5j' mRNA 981 1134 846 15.35 17.47 14.05 5.31 4.33 4.29 15.62333333 4.643333333 390 311 305 987 335.3333333 7.25E-38 -1.566319066 00562///Inositol phosphate metabolism GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0030426///growth cone+++GO:0043198///dendritic shaft "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity" GO:0010977///negative regulation of neuron projection development+++GO:0031115///negative regulation of microtubule polymerization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation 17084 17084 'Ly86' mRNA 160 189 212 10.27 12 14.44 144.37 133.01 134.68 12.23666667 137.3533333 2579.03 2316 2325.02 187 2406.683333 5.65E-256 3.670795359 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045087///innate immune response 17085 17085 'Ly9' mRNA 7 11 7 0.16 0.26 0.17 10.71 9.75 11.94 0.196666667 10.8 548 485 595 8.333333333 542.6666667 5.65E-76 6.014517804 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007155///cell adhesion+++GO:0032740///positive regulation of interleukin-17 production+++GO:0042110///T cell activation+++GO:0045087///innate immune response+++GO:0072540///T-helper 17 cell lineage commitment 17086 17086 'Ncr1' mRNA 6 2 4 0.24 0.08 0.17 0.14 0.11 0.33 0.163333333 0.193333333 4 3 9 4 5.333333333 0.800528149 0.400870217 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0009597///detection of virus+++GO:0051607///defense response to virus 17087 17087 'Ly96' mRNA 68 98 75 8.6 12.34 10.07 45.73 48.71 45.26 10.33666667 46.56666667 412 427 393 80.33333333 410.6666667 2.57E-39 2.344612625 04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04936///Alcoholic liver disease+++05132///Salmonella infection+++05133///Pertussis+++05145///Toxoplasmosis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031226///intrinsic component of plasma membrane+++GO:0046696///lipopolysaccharide receptor complex GO:0001530///lipopolysaccharide binding+++GO:0001875///lipopolysaccharide receptor activity+++GO:0005515///protein binding+++GO:0035662///Toll-like receptor 4 binding GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032497///detection of lipopolysaccharide+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0071222///cellular response to lipopolysaccharide 17089 17089 'Lyar' mRNA 398 434 425 14.96 16.16 17.01 15.64 15.43 17.14 16.04333333 16.07 484 463 508 419 485 0.151734653 0.198377111 GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0042995///cell projection GO:0003677///DNA binding+++GO:0033613///activating transcription factor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002376///immune system process+++GO:0006364///rRNA processing+++GO:0045087///innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0048821///erythrocyte development+++GO:0050766///positive regulation of phagocytosis 170930 170930 'Sumo2' mRNA 4913.72 5051.76 4805.88 314.94 320.22 326.84 405.45 394.13 395.27 320.6666667 398.2833333 7252.49 6871.42 6832.64 4923.786667 6985.516667 2.31E-20 0.492619773 03013///Nucleocytoplasmic transport+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body GO:0005515///protein binding+++GO:0019789///SUMO transferase activity+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046965///retinoid X receptor binding "GO:0016925///protein sumoylation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033235///positive regulation of protein sumoylation+++GO:0034613///cellular protein localization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 170935 170935 'Grid2ip' mRNA 168 177 134 2.19 2.35 1.9 0.16 0.3 0.57 2.146666667 0.343333333 14 25 49 159.6666667 29.33333333 7.91E-13 -2.446870468 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005515///protein binding GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0060292///long-term synaptic depression 170936 170936 'Zfp369' mRNA 2157.25 2115.84 1858.77 5.08 4.94 4.52 3.57 2.84 3.41 4.846666667 3.273333333 1536.64 1323.42 1434.47 2043.953333 1431.51 5.80E-12 -0.524444996 04722///Neurotrophin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0051726///regulation of cell cycle+++GO:1900112///regulation of histone H3-K9 trimethylation" 170938 170938 'Zfp617' mRNA 1117.28 1067.73 1003.56 20.84 19.6 19.86 15.12 14.14 12.39 20.1 13.88333333 932.42 851.57 739.93 1062.856667 841.3066667 7.06E-04 -0.349439885 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 170947 170947 'Myoz3' mRNA 2 3.88 3 0.03 0.06 0.05 0.06 0.03 0.09 0.046666667 0.06 4 2 6 2.96 4 0.749787559 0.56796658 GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031433///telethonin binding+++GO:0051373///FATZ binding 17095 17095 'Lyl1' mRNA 120.05 92.79 115.16 3.65 2.81 3.49 23.95 24.41 24.81 3.316666667 24.39 942.08 923.01 948 109.3333333 937.6966667 4.42E-114 3.091625639 05202///Transcriptional misregulation in cancer GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity" "GO:0001955///blood vessel maturation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030183///B cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060216///definitive hemopoiesis" 170952 170952 'Prima1' mRNA 33 40 34 0.53 0.82 0.56 0.28 0.19 0.25 0.636666667 0.24 20 13 17 35.66666667 16.66666667 0.028837384 -1.110604088 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031226///intrinsic component of plasma membrane+++GO:0045202///synapse GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0043495///protein membrane anchor GO:0042135///neurotransmitter catabolic process+++GO:0051649///establishment of localization in cell 17096 17096 'Lyn' mRNA 355 310 338 5.59 4.67 5.54 36.45 33.83 33.97 5.266666667 34.75 2651 2417 2408 334.3333333 2492 5.46E-226 2.884682892 04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04611///Platelet activation+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04730///Long-term depression+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis+++05417///Lipid and atherosclerosis "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030061///mitochondrial crista+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0034666///integrin alpha2-beta1 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005128///erythropoietin receptor binding+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043015///gamma-tubulin binding+++GO:0043208///glycosphingolipid binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046875///ephrin receptor binding+++GO:0051219///phosphoprotein binding+++GO:0097110///scaffold protein binding+++GO:0140031///phosphorylation-dependent protein binding GO:0001782///B cell homeostasis+++GO:0001817///regulation of cytokine production+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002431///Fc receptor mediated stimulatory signaling pathway+++GO:0002513///tolerance induction to self antigen+++GO:0002553///histamine secretion by mast cell+++GO:0002576///platelet degranulation+++GO:0002762///negative regulation of myeloid leukocyte differentiation+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0002774///Fc receptor mediated inhibitory signaling pathway+++GO:0002902///regulation of B cell apoptotic process+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006991///response to sterol depletion+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009636///response to toxic substance+++GO:0009725///response to hormone+++GO:0009743///response to carbohydrate+++GO:0010976///positive regulation of neuron projection development+++GO:0014003///oligodendrocyte development+++GO:0014070///response to organic cyclic compound+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030889///negative regulation of B cell proliferation+++GO:0031175///neuron projection development+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0032868///response to insulin+++GO:0033003///regulation of mast cell activation+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0034605///cellular response to heat+++GO:0035556///intracellular signal transduction+++GO:0042327///positive regulation of phosphorylation+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042541///hemoglobin biosynthetic process+++GO:0043200///response to amino acid+++GO:0043304///regulation of mast cell degranulation+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043434///response to peptide hormone+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045087///innate immune response+++GO:0045646///regulation of erythrocyte differentiation+++GO:0046777///protein autophosphorylation+++GO:0048678///response to axon injury+++GO:0050727///regulation of inflammatory response+++GO:0050853///B cell receptor signaling pathway+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0051272///positive regulation of cellular component movement+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060369///positive regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0070304///positive regulation of stress-activated protein kinase signaling cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0070667///negative regulation of mast cell proliferation+++GO:0070668///positive regulation of mast cell proliferation+++GO:0071300///cellular response to retinoic acid+++GO:0090025///regulation of monocyte chemotaxis+++GO:0090330///regulation of platelet aggregation+++GO:0097028///dendritic cell differentiation+++GO:1902532///negative regulation of intracellular signal transduction+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:2000670///positive regulation of dendritic cell apoptotic process 17101 17101 'Lyst' mRNA 445 530 440 1.73 2.03 1.81 1.68 1.67 1.74 1.856666667 1.696666667 497 482 500 471.6666667 493 0.748070175 0.054001293 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane GO:0019901///protein kinase binding GO:0002446///neutrophil mediated immunity+++GO:0002456///T cell mediated immunity+++GO:0006644///phospholipid metabolic process+++GO:0006909///phagocytosis+++GO:0007017///microtubule-based process+++GO:0007040///lysosome organization+++GO:0007596///blood coagulation+++GO:0008104///protein localization+++GO:0009410///response to xenobiotic stimulus+++GO:0015031///protein transport+++GO:0030595///leukocyte chemotaxis+++GO:0032438///melanosome organization+++GO:0032510///endosome to lysosome transport via multivesicular body sorting pathway+++GO:0032816///positive regulation of natural killer cell activation+++GO:0033299///secretion of lysosomal enzymes+++GO:0033364///mast cell secretory granule organization+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042493///response to drug+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0043473///pigmentation+++GO:0048753///pigment granule organization+++GO:0051607///defense response to virus+++GO:0055091///phospholipid homeostasis 17105 17105 'Lyz2' mRNA 3633.81 3676 3876.87 216.92 216.91 245.56 7762.73 8050.17 7677.09 226.4633333 7829.996667 149138.43 150774.26 142561.32 3728.893333 147491.3367 0 5.29205536 04970///Salivary secretion GO:0000137///Golgi cis cisterna+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005795///Golgi stack+++GO:0005902///microvillus+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030141///secretory granule+++GO:0048237///rough endoplasmic reticulum lumen "GO:0003796///lysozyme activity+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0042802///identical protein binding" GO:0008152///metabolic process+++GO:0019835///cytolysis+++GO:0031640///killing of cells of other organism+++GO:0042742///defense response to bacterium+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 171095 171095 'Il17rc' mRNA 1242 1090 1155 30.11 25.6 29.74 21.12 21.02 22.58 28.48333333 21.57333333 1009 988 1051 1162.333333 1016 0.038693459 -0.206781707 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway+++04936///Alcoholic liver disease GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030368///interleukin-17 receptor activity GO:0006954///inflammatory response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032755///positive regulation of interleukin-6 production+++GO:0050832///defense response to fungus+++GO:0071621///granulocyte chemotaxis+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 17110 17110 'Lyz1' mRNA 298.19 326 323.13 14.33 15.47 16.48 589.37 577.17 570.14 15.42666667 578.8933333 14075.57 13444.74 13167.68 315.7733333 13562.66333 0 5.412944033 04970///Salivary secretion GO:0000137///Golgi cis cisterna+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005795///Golgi stack+++GO:0005902///microvillus+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030141///secretory granule+++GO:0048237///rough endoplasmic reticulum lumen "GO:0003796///lysozyme activity+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0042802///identical protein binding" GO:0008152///metabolic process+++GO:0019835///cytolysis+++GO:0031640///killing of cells of other organism+++GO:0042742///defense response to bacterium+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 17112 17112 'Tm4sf1' mRNA 3126 3193 3041 132.92 133.72 135.03 434.59 431.11 461.94 133.89 442.5466667 11497 11136 11788 3120 11473.66667 2.30E-270 1.867091025 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001825///blastocyst formation 17113 17113 'M6pr' mRNA 3579 3632 3660 79.24 79.17 85.97 105.57 103.37 101.08 81.46 103.34 5484 5244 5084 3623.666667 5270.666667 2.71E-17 0.52717668 04142///Lysosome+++04145///Phagosome+++05132///Salmonella infection GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:1905394///retromer complex binding GO:0006622///protein targeting to lysosome+++GO:0006886///intracellular protein transport+++GO:0007041///lysosomal transport+++GO:0033299///secretion of lysosomal enzymes 17116 17116 'Mab21l1' mRNA 37 45 22 0.74 0.88 0.46 0.52 0.85 0.68 0.693333333 0.683333333 30 48 38 34.66666667 38.66666667 0.78712742 0.161038954 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0001654///eye development+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0043010///camera-type eye development 171166 171166 'Mcoln3' mRNA 4835 5265 4988 87.98 95.22 96.18 57.78 60.17 58.68 93.12666667 58.87666667 3641 3696 3603 5029.333333 3646.666667 3.29E-14 -0.47565347 04020///Calcium signaling pathway GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0060171///stereocilium membrane GO:0005261///cation channel activity+++GO:0008289///lipid binding+++GO:0072345///NAADP-sensitive calcium-release channel activity GO:0006811///ion transport+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0034220///ion transmembrane transport+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0098655///cation transmembrane transport 171167 171167 'Fut10' mRNA 289 299 231 4.54 5.1 4.19 2.36 3.75 2.9 4.61 3.003333333 157 242 206 273 201.6666667 0.032322202 -0.440366309 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0036065///fucosylation+++GO:0097150///neuronal stem cell population maintenance 171168 171168 'Acer1' mRNA 8.31 7.33 6.81 0.19 0.17 0.17 0.07 0.08 0.16 0.176666667 0.103333333 3.34 3.78 7.84 7.483333333 4.986666667 0.587375182 -0.698485206 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005125///cytokine activity+++GO:0016015///morphogen activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0036122///BMP binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0071633///dihydroceramidase activity+++GO:0102121///ceramidase activity" GO:0001657///ureteric bud development+++GO:0003419///growth plate cartilage chondrocyte proliferation+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0007165///signal transduction+++GO:0007369///gastrulation+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010446///response to alkaline pH+++GO:0019216///regulation of lipid metabolic process+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030148///sphingolipid biosynthetic process+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030282///bone mineralization+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0033561///regulation of water loss via skin+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0042074///cell migration involved in gastrulation+++GO:0046512///sphingosine biosynthetic process+++GO:0046514///ceramide catabolic process+++GO:0048263///determination of dorsal identity+++GO:0048733///sebaceous gland development+++GO:0061371///determination of heart left/right asymmetry+++GO:0071276///cellular response to cadmium ion+++GO:0071277///cellular response to calcium ion+++GO:0071773///cellular response to BMP stimulus+++GO:1900176///negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:2000381///negative regulation of mesoderm development 17117 17117 'Amacr' mRNA 421 471 494 14.45 16.58 17.85 13.93 12.29 13.62 16.29333333 13.28 450 375 437 462 420.6666667 0.346788323 -0.150928444 00120///Primary bile acid biosynthesis+++04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0008111///alpha-methylacyl-CoA racemase activity+++GO:0008410///CoA-transferase activity+++GO:0016853///isomerase activity GO:0006631///fatty acid metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0008206///bile acid metabolic process+++GO:0008300///isoprenoid catabolic process 171170 171170 'Mbnl3' mRNA 28 37 23 0.14 0.2 0.15 0.47 0.36 0.52 0.163333333 0.45 95 71.18 99 29.33333333 88.39333333 4.22E-06 1.582725359 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0046872///metal ion binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0045662///negative regulation of myoblast differentiation" 171171 171171 'Ntng2' mRNA 100 79 41 3.21 2.54 1.42 0.89 0.56 0.71 2.39 0.72 32 19 24 73.33333333 25 2.04E-04 -1.554073678 04360///Axon guidance+++04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0043256///laminin complex+++GO:0045171///intercellular bridge+++GO:0046658///anchored component of plasma membrane+++GO:0090543///Flemming body+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099029///anchored component of presynaptic active zone membrane GO:0003674///molecular_function+++GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0010975///regulation of neuron projection development+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0050804///modulation of chemical synaptic transmission+++GO:0070831///basement membrane assembly+++GO:0098698///postsynaptic specialization assembly+++GO:0099560///synaptic membrane adhesion+++GO:0150011///regulation of neuron projection arborization+++GO:1905606///regulation of presynapse assembly+++GO:2001222///regulation of neuron migration 17118 17118 'Marcks' mRNA 338 337 339 4.35 4.26 4.63 19.3 15.86 19.41 4.413333333 18.19 1727 1386 1682 338 1598.333333 2.29E-100 2.227636486 04666///Fc gamma R-mediated phagocytosis+++05206///MicroRNAs in cancer GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0032059///bleb+++GO:0032432///actin filament bundle+++GO:0033391///chromatoid body+++GO:0042585///germinal vesicle+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0044307///dendritic branch+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099025///anchored component of postsynaptic membrane+++GO:0099026///anchored component of presynaptic membrane+++GO:0099523///presynaptic cytosol+++GO:0099571///postsynaptic cytoskeleton GO:0001786///phosphatidylserine binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0006886///intracellular protein transport+++GO:0007015///actin filament organization+++GO:0007417///central nervous system development+++GO:0010976///positive regulation of neuron projection development+++GO:0031584///activation of phospholipase D activity+++GO:0031589///cell-substrate adhesion+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0051017///actin filament bundle assembly+++GO:0051764///actin crosslink formation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:1900020///positive regulation of protein kinase C activity+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton 171180 171180 'Syt12' mRNA 613.92 634.49 586.16 10.23 10.4 10.36 9.13 9.53 10.21 10.33 9.623333333 630.52 643.02 683 611.5233333 652.18 0.529888445 0.083140151 GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0070382///exocytic vesicle+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048792///spontaneous exocytosis of neurotransmitter+++GO:0060291///long-term synaptic potentiation+++GO:0071277///cellular response to calcium ion 171188 171188 'Vmn1r32' mRNA 0 2 0 0 0.05 0 0 0.04 0 0.016666667 0.013333333 0 2 0 0.666666667 0.666666667 0.998257897 0.050926121 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 17119 17119 'Mxd1' mRNA 492 476 536 5.65 5.37 6.53 5.22 5.14 5.22 5.85 5.193333333 523 504 507 501.3333333 511.3333333 0.936365601 0.01349555 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 171192 171192 'Vmn1r5' mRNA 0 1 1 0 0.06 0.06 0 0 0 0.04 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 171194 171194 'Vmn1r4' mRNA 0 3 1 0 0.15 0.08 0 0 0 0.076666667 0 0 0 0 1.333333333 0 0.484689396 -2.854031813 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 17120 17120 'Mad1l1' mRNA 534.8 513 428 9.42 8.86 8.02 9.77 11.52 10.37 8.766666667 10.55333333 659 700.82 662.4 491.9333333 674.0733333 1.15E-04 0.446538588 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0044615///nuclear pore nuclear basket+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole" GO:0042802///identical protein binding+++GO:0043515///kinetochore binding GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0042130///negative regulation of T cell proliferation+++GO:0048538///thymus development+++GO:0051220///cytoplasmic sequestering of protein+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0090235///regulation of metaphase plate congression+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:1902426///deactivation of mitotic spindle assembly checkpoint 171201 171201 'Vmn1r21' mRNA 1 0 0 0.07 0 0 0.06 0 0 0.023333333 0.02 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 171207 171207 'Arhgap4' mRNA 126 75 102 2.08 1.4 1.91 6 5.26 6.44 1.796666667 5.9 405 355 405 101 388.3333333 5.96E-24 1.928511472 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0030426///growth cone GO:0005096///GTPase activator activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0010764///negative regulation of fibroblast migration+++GO:0030336///negative regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0050790///regulation of catalytic activity 171209 171209 'Asic3' mRNA 14 7 7 0.41 0.21 0.24 0.08 0.03 0.17 0.286666667 0.093333333 3 1 6 9.333333333 3.333333333 0.197058548 -1.493601841 04750///Inflammatory mediator regulation of TRP channels GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0042931///enterobactin transmembrane transporter activity+++GO:0044736///acid-sensing ion channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0009408///response to heat+++GO:0009612///response to mechanical stimulus+++GO:0010447///response to acidic pH+++GO:0034220///ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042930///enterobactin transport+++GO:0050907///detection of chemical stimulus involved in sensory perception+++GO:0050915///sensory perception of sour taste+++GO:0050961///detection of temperature stimulus involved in sensory perception+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0050968///detection of chemical stimulus involved in sensory perception of pain+++GO:0050974///detection of mechanical stimulus involved in sensory perception 17121 17121 'Mxd3' mRNA 5 5 5 0.23 0.23 0.25 3.9 2.96 3.95 0.236666667 3.603333333 96 71 94 5 87 3.69E-16 4.107747729 GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 171210 171210 'Acot2' mRNA 875.54 968.44 815.9 22.44 24.44 22.18 13.9 12.36 12.75 23.02 13.00333333 623.67 541.52 553.7 886.6266667 572.9633333 3.33E-10 -0.641024368 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++04913///Ovarian steroidogenesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001666///response to hypoxia+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0042760///very long-chain fatty acid catabolic process 171211 171211 'Edaradd' mRNA 267 240 213 2.14 1.93 2.18 0.52 0.32 0.47 2.083333333 0.436666667 69 46 67 240 60.66666667 1.74E-19 -1.995056638 04064///NF-kappa B signaling pathway GO:0005737///cytoplasm GO:0005123///death receptor binding+++GO:0005515///protein binding GO:0001942///hair follicle development+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0061153///trachea gland development+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 171212 171212 'Galnt10' mRNA 526 475 343 6.21 5.32 4.14 2.81 2.4 3.07 5.223333333 2.76 273 234 288 448 265 2.49E-06 -0.762954633 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0008150///biological_process+++GO:0016266///O-glycan processing 17122 17122 'Mxd4' mRNA 337 423 147 17.62 21.84 8.15 10.07 13.83 12.82 15.87 12.24 221 296 272 302.3333333 263 0.750387006 -0.189109562 GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 17123 17123 'Madcam1' mRNA 1 1 5 0.06 0.06 0.34 0 0.15 0 0.153333333 0.05 0 4 0 2.333333333 1.333333333 0.755246974 -0.83837955 04514///Cell adhesion molecules+++04672///Intestinal immune network for IgA production GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0098640///integrin binding involved in cell-matrix adhesion GO:0002687///positive regulation of leukocyte migration+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0030216///keratinocyte differentiation+++GO:0034113///heterotypic cell-cell adhesion+++GO:0043113///receptor clustering+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:2000403///positive regulation of lymphocyte migration 171235 171235 'Vmn1r236' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 17125 17125 'Smad1' mRNA 189 177 165 3.45 3.18 3.19 4.49 4.14 5.29 3.273333333 4.64 285 255 324 177 288 6.79E-05 0.691540191 04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0071144///heteromeric SMAD protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070410///co-SMAD binding+++GO:0070411///I-SMAD binding+++GO:0070878///primary miRNA binding" "GO:0000165///MAPK cascade+++GO:0001649///osteoblast differentiation+++GO:0001657///ureteric bud development+++GO:0001710///mesodermal cell fate commitment+++GO:0002051///osteoblast fate commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007183///SMAD protein complex assembly+++GO:0007276///gamete generation+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009653///anatomical structure morphogenesis+++GO:0009880///embryonic pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0042493///response to drug+++GO:0042592///homeostatic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0051216///cartilage development+++GO:0060038///cardiac muscle cell proliferation+++GO:0060348///bone development+++GO:0060395///SMAD protein signal transduction+++GO:0061036///positive regulation of cartilage development+++GO:0071407///cellular response to organic cyclic compound+++GO:0071773///cellular response to BMP stimulus+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903672///positive regulation of sprouting angiogenesis" 171256 171256 'Vmn1r218' mRNA 0 4 0 0 0.29 0 0 0 0 0.096666667 0 0 0 0 1.333333333 0 0.542051645 -2.822701071 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 17126 17126 'Smad2' mRNA 888 913 790 5.22 5.28 4.99 5.04 4.48 5.07 5.163333333 4.863333333 986 846 952 863.6666667 928 0.413094471 0.093049353 04110///Cell cycle+++04144///Endocytosis+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04371///Apelin signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04659///Th17 cell differentiation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05142///Chagas disease+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05321///Inflammatory bowel disease+++05415///Diabetic cardiomyopathy GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032444///activin responsive factor complex+++GO:0032991///protein-containing complex+++GO:0071141///SMAD protein complex+++GO:0071144///heteromeric SMAD protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019902///phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048156///tau protein binding+++GO:0070410///co-SMAD binding+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding+++GO:0097718///disordered domain specific binding" "GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001706///endoderm formation+++GO:0001707///mesoderm formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007183///SMAD protein complex assembly+++GO:0007352///zygotic specification of dorsal/ventral axis+++GO:0007369///gastrulation+++GO:0007389///pattern specification process+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0009749///response to glucose+++GO:0009791///post-embryonic development+++GO:0009880///embryonic pattern specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030073///insulin secretion+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030325///adrenal gland development+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031016///pancreas development+++GO:0032924///activin receptor signaling pathway+++GO:0035265///organ growth+++GO:0035556///intracellular signal transduction+++GO:0038092///nodal signaling pathway+++GO:0042060///wound healing+++GO:0045165///cell fate commitment+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048340///paraxial mesoderm morphogenesis+++GO:0048589///developmental growth+++GO:0048617///embryonic foregut morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0051098///regulation of binding+++GO:0060039///pericardium development+++GO:0060395///SMAD protein signal transduction+++GO:0062009///secondary palate development+++GO:0070723///response to cholesterol+++GO:1900224///positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" 171267 171267 'Vmn1r84' mRNA 0 2 0 0 0.13 0 0 0 0 0.043333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 17127 17127 'Smad3' mRNA 951 966 914 10.56 10.51 10.94 8.57 9.51 8.84 10.67 8.973333333 889 973 933 943.6666667 931.6666667 0.831159379 -0.028951317 04068///FoxO signaling pathway+++04110///Cell cycle+++04144///Endocytosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04350///TGF-beta signaling pathway+++04371///Apelin signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04659///Th17 cell differentiation+++04933///AGE-RAGE signaling pathway in diabetic complications+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05321///Inflammatory bowel disease+++05415///Diabetic cardiomyopathy GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0071141///SMAD protein complex+++GO:0071144///heteromeric SMAD protein complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031962///mineralocorticoid receptor binding+++GO:0032810///sterol response element binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043130///ubiquitin binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070410///co-SMAD binding+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001657///ureteric bud development+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0001756///somitogenesis+++GO:0001889///liver development+++GO:0001947///heart looping+++GO:0002076///osteoblast development+++GO:0002520///immune system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006955///immune response+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007183///SMAD protein complex assembly+++GO:0007254///JNK cascade+++GO:0007369///gastrulation+++GO:0007492///endoderm development+++GO:0008285///negative regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0009880///embryonic pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016202///regulation of striated muscle tissue development+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030878///thyroid gland development+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032909///regulation of transforming growth factor beta2 production+++GO:0032916///positive regulation of transforming growth factor beta3 production+++GO:0032924///activin receptor signaling pathway+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0038092///nodal signaling pathway+++GO:0042110///T cell activation+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045216///cell-cell junction organization+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048340///paraxial mesoderm morphogenesis+++GO:0048589///developmental growth+++GO:0048617///embryonic foregut morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0050776///regulation of immune response+++GO:0050821///protein stabilization+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051098///regulation of binding+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051726///regulation of cell cycle+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060039///pericardium development+++GO:0060290///transdifferentiation+++GO:0060395///SMAD protein signal transduction+++GO:0061045///negative regulation of wound healing+++GO:0061767///negative regulation of lung blood pressure+++GO:0070306///lens fiber cell differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097296///activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0098586///cellular response to virus+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress" 17128 17128 'Smad4' mRNA 611 663 651 4.82 5.41 5.55 5.16 5.12 5.27 5.26 5.183333333 717 683 720 641.6666667 706.6666667 0.302250896 0.126350708 04068///FoxO signaling pathway+++04110///Cell cycle+++04310///Wnt signaling pathway+++04350///TGF-beta signaling pathway+++04371///Apelin signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04659///Th17 cell differentiation+++04933///AGE-RAGE signaling pathway in diabetic complications+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0032444///activin responsive factor complex+++GO:0032991///protein-containing complex+++GO:0071141///SMAD protein complex+++GO:0071144///heteromeric SMAD protein complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0031005///filamin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043199///sulfate binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0001649///osteoblast differentiation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001702///gastrulation with mouth forming second+++GO:0001822///kidney development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003190///atrioventricular valve formation+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003220///left ventricular cardiac muscle tissue morphogenesis+++GO:0003251///positive regulation of cell proliferation involved in heart valve morphogenesis+++GO:0003279///cardiac septum development+++GO:0003360///brainstem development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006879///cellular iron ion homeostasis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007183///SMAD protein complex assembly+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007369///gastrulation+++GO:0007411///axon guidance+++GO:0007492///endoderm development+++GO:0007498///mesoderm development+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009653///anatomical structure morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0014033///neural crest cell differentiation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030509///BMP signaling pathway+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032525///somite rostral/caudal axis specification+++GO:0032909///regulation of transforming growth factor beta2 production+++GO:0033686///positive regulation of luteinizing hormone secretion+++GO:0035556///intracellular signal transduction+++GO:0036302///atrioventricular canal development+++GO:0042060///wound healing+++GO:0042118///endothelial cell activation+++GO:0042127///regulation of cell proliferation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042733///embryonic digit morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048382///mesendoderm development+++GO:0048589///developmental growth+++GO:0048663///neuron fate commitment+++GO:0048729///tissue morphogenesis+++GO:0048733///sebaceous gland development+++GO:0048859///formation of anatomical boundary+++GO:0051098///regulation of binding+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051797///regulation of hair follicle development+++GO:0060065///uterus development+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060956///endocardial cell differentiation+++GO:0061040///female gonad morphogenesis+++GO:0062009///secondary palate development+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071333///cellular response to glucose stimulus+++GO:0071559///response to transforming growth factor beta+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0072134///nephrogenic mesenchyme morphogenesis+++GO:0072520///seminiferous tubule development+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1905305///negative regulation of cardiac myofibril assembly+++GO:2000617///positive regulation of histone H3-K9 acetylation" 171281 171281 'Acot3' mRNA 6.02 1.01 3.01 0.13 0.02 0.07 0.17 0.17 0.15 0.073333333 0.163333333 9.06 9.04 8.04 3.346666667 8.713333333 0.246120803 1.365520802 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++04913///Ovarian steroidogenesis GO:0005777///peroxisome+++GO:0005829///cytosol GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0032788///saturated monocarboxylic acid metabolic process+++GO:0032789///unsaturated monocarboxylic acid metabolic process 171282 171282 'Acot4' mRNA 17 10 17 0.45 0.26 0.48 0.26 0.4 0.5 0.396666667 0.386666667 12 18 22 14.66666667 17.33333333 0.793454649 0.226305082 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++04913///Ovarian steroidogenesis GO:0005777///peroxisome GO:0004778///succinyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0044466///glutaryl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0032788///saturated monocarboxylic acid metabolic process+++GO:0032789///unsaturated monocarboxylic acid metabolic process+++GO:0043648///dicarboxylic acid metabolic process+++GO:0043649///dicarboxylic acid catabolic process+++GO:0046459///short-chain fatty acid metabolic process 171284 171284 'Timd2' mRNA 55 44 37 1.3 1.07 1.01 0.27 0.55 0.47 1.126666667 0.43 17 25 21 45.33333333 21 0.014642626 -1.114687855 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium GO:0001618///virus receptor activity+++GO:0001786///phosphatidylserine binding+++GO:0070287///ferritin receptor activity "GO:0006826///iron ion transport+++GO:0006911///phagocytosis, engulfment+++GO:0033005///positive regulation of mast cell activation+++GO:0046718///viral entry into host cell" 171285 171285 'Havcr2' mRNA 14 14 9 0.28 0.28 0.19 8.81 9.02 8.68 0.25 8.836666667 499 499 476 12.33333333 491.3333333 1.72E-80 5.306778102 GO:0001772///immunological synapse+++GO:0005576///extracellular region+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001819///positive regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0002519///natural killer cell tolerance induction+++GO:0002652///regulation of tolerance induction dependent upon immune response+++GO:0002826///negative regulation of T-helper 1 type immune response+++GO:0002838///negative regulation of immune response to tumor cell+++GO:0002859///negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0006954///inflammatory response+++GO:0010629///negative regulation of gene expression+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032480///negative regulation of type I interferon production+++GO:0032687///negative regulation of interferon-alpha production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032712///negative regulation of interleukin-3 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043032///positive regulation of macrophage activation+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060135///maternal process involved in female pregnancy+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071656///negative regulation of granulocyte colony-stimulating factor production+++GO:1900425///negative regulation of defense response to bacterium+++GO:1900426///positive regulation of defense response to bacterium+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000521///negative regulation of immunological synapse formation+++GO:2001189///negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 171286 171286 'Slc12a8' mRNA 41.79 41.44 42.14 0.88 0.87 0.92 0.75 0.72 0.65 0.89 0.706666667 41.95 39.08 34.25 41.79 38.42666667 0.800059835 -0.13467139 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006884///cell volume homeostasis+++GO:0015698///inorganic anion transport+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 17129 17129 'Smad5' mRNA 1598 1553 1474 12.84 12.25 12.54 13.59 12.92 13.77 12.54333333 13.42666667 1951 1812 1916 1541.666667 1893 1.08E-04 0.284641595 04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0071144///heteromeric SMAD protein complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0070411///I-SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001657///ureteric bud development+++GO:0001880///Mullerian duct regression+++GO:0002051///osteoblast fate commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0009653///anatomical structure morphogenesis+++GO:0009880///embryonic pattern specification+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030509///BMP signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development+++GO:0060048///cardiac muscle contraction+++GO:0060348///bone development+++GO:0060395///SMAD protein signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0071773///cellular response to BMP stimulus+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" 17130 17130 'Smad6' mRNA 73 83 63 1.35 1.51 1.27 0.72 0.89 0.51 1.376666667 0.706666667 44 54 31 73 43 0.032028625 -0.770078227 04350///TGF-beta signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0071144///heteromeric SMAD protein complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070410///co-SMAD binding+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding+++GO:0070698///type I activin receptor binding "GO:0001657///ureteric bud development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003170///heart valve development+++GO:0003180///aortic valve morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003281///ventricular septum development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006955///immune response+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007352///zygotic specification of dorsal/ventral axis+++GO:0008285///negative regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0010991///negative regulation of SMAD protein complex assembly+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031589///cell-substrate adhesion+++GO:0032496///response to lipopolysaccharide+++GO:0034616///response to laminar fluid shear stress+++GO:0035904///aorta development+++GO:0042310///vasoconstriction+++GO:0043066///negative regulation of apoptotic process+++GO:0043627///response to estrogen+++GO:0045444///fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0060948///cardiac vascular smooth muscle cell development+++GO:0060976///coronary vasculature development+++GO:0060977///coronary vasculature morphogenesis+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 17131 17131 'Smad7' mRNA 258 245 212 3.99 3.81 3.63 2.77 2.29 2.48 3.81 2.513333333 200 160 174 238.3333333 178 0.019826267 -0.431764232 04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016342///catenin complex+++GO:0032991///protein-containing complex+++GO:0071144///heteromeric SMAD protein complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008013///beta-catenin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0070411///I-SMAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0002725///negative regulation of T cell cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0009653///anatomical structure morphogenesis+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031503///protein-containing complex localization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032925///regulation of activin receptor signaling pathway+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0034333///adherens junction assembly+++GO:0034616///response to laminar fluid shear stress+++GO:0034629///cellular protein-containing complex localization+++GO:0035556///intracellular signal transduction+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0048844///artery morphogenesis+++GO:0050821///protein stabilization+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1902731///negative regulation of chondrocyte proliferation+++GO:1903043///positive regulation of chondrocyte hypertrophy+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000317///negative regulation of T-helper 17 type immune response+++GO:2000320///negative regulation of T-helper 17 cell differentiation" 17132 17132 'Maf' mRNA 758 798 594 11.29 11.69 9.39 24.52 19.31 22.03 10.79 21.95333333 1894 1457 1648 716.6666667 1666.333333 8.58E-31 1.208442507 04658///Th1 and Th2 cell differentiation+++05202///Transcriptional misregulation in cancer+++05321///Inflammatory bowel disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001816///cytokine production+++GO:0002088///lens development in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0032330///regulation of chondrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0048839///inner ear development+++GO:0070306///lens fiber cell differentiation" 17133 17133 'Maff' mRNA 58 42 34 1.68 1.21 1.07 2.3 2.1 1.73 1.32 2.043333333 89 81 66 44.66666667 78.66666667 0.019516041 0.809085735 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035914///skeletal muscle cell differentiation+++GO:0045604///regulation of epidermal cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 17134 17134 'Mafg' mRNA 1144 1229 1075 10.59 11.34 10.22 13.73 14.34 14.45 10.71666667 14.17333333 1542 1495 1521 1149.333333 1519.333333 5.52E-07 0.392411166 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0030534///adult behavior+++GO:0030641///regulation of cellular pH+++GO:0042127///regulation of cell proliferation+++GO:0045604///regulation of epidermal cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 17135 17135 'Mafk' mRNA 803 810 794 12.53 13.32 13.85 19.73 17.68 18.19 13.23333333 18.53333333 1325 1169 1247 802.3333333 1247 1.52E-12 0.623238766 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0071535///RING-like zinc finger domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development" 17136 17136 'Mag' mRNA 1004 1098 977 22.65 24.4 23.3 18.25 15.93 15.45 23.45 16.54333333 935 792 765 1026.333333 830.6666667 0.001833491 -0.317306725 04514///Cell adhesion molecules GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033270///paranode region of axon+++GO:0035749///myelin sheath adaxonal region+++GO:0043209///myelin sheath+++GO:0043218///compact myelin+++GO:0043220///Schmidt-Lanterman incisure+++GO:0045121///membrane raft+++GO:0097453///mesaxon GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0042803///protein homodimerization activity+++GO:1905576///ganglioside GT1b binding GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0010977///negative regulation of neuron projection development+++GO:0019226///transmission of nerve impulse+++GO:0022010///central nervous system myelination+++GO:0030517///negative regulation of axon extension+++GO:0031103///axon regeneration+++GO:0031643///positive regulation of myelination+++GO:0032289///central nervous system myelin formation+++GO:0042552///myelination+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0071260///cellular response to mechanical stimulus+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 171382 171382 'Trpm8' mRNA 1 1 4 0.03 0.03 0.11 0 0 0.07 0.056666667 0.023333333 0 0 3 2 1 0.721494714 -1.040266379 04750///Inflammatory mediator regulation of TRP channels GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0099604///ligand-gated calcium channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0009266///response to temperature stimulus+++GO:0009409///response to cold+++GO:0016048///detection of temperature stimulus+++GO:0019722///calcium-mediated signaling+++GO:0050896///response to stimulus+++GO:0050951///sensory perception of temperature stimulus+++GO:0050955///thermoception+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:0120162///positive regulation of cold-induced thermogenesis 171388 171388 'Bnipl' mRNA 36.82 24.66 27.75 1.23 0.82 0.98 0.18 0.86 0.73 1.01 0.59 6.3 28 25 29.74333333 19.76666667 0.417790325 -0.561918744 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004309///exopolyphosphatase activity+++GO:0042802///identical protein binding GO:0006798///polyphosphate catabolic process+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0040009///regulation of growth rate 171395 171395 'Pkd1l1' mRNA 65 77 50 0.43 0.5 0.35 0.09 0.09 0.08 0.426666667 0.086666667 15 15 13 64 14.33333333 3.26E-07 -2.163401783 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034704///calcium channel complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0005262///calcium channel activity+++GO:0005515///protein binding GO:0003127///detection of nodal flow+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0050982///detection of mechanical stimulus+++GO:0060972///left/right pattern formation+++GO:0070588///calcium ion transmembrane transport+++GO:0070986///left/right axis specification 171429 171429 'Slc26a6' mRNA 104 87 118 1.72 1.58 2.31 2.26 2.2 2.31 1.87 2.256666667 150 142 148 103 146.6666667 0.046724412 0.492521028 04978///Mineral absorption+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031982///vesicle+++GO:0034707///chloride channel complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097225///sperm midpiece GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0015499///formate transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0015660///formate efflux transmembrane transporter activity+++GO:0019531///oxalate transmembrane transporter activity+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0008272///sulfate transport+++GO:0015701///bicarbonate transport+++GO:0015724///formate transport+++GO:0015797///mannitol transport+++GO:0019532///oxalate transport+++GO:0030321///transepithelial chloride transport+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042045///epithelial fluid transport+++GO:0046724///oxalic acid secretion+++GO:0048240///sperm capacitation+++GO:0050892///intestinal absorption+++GO:0051453///regulation of intracellular pH+++GO:0051454///intracellular pH elevation+++GO:0055085///transmembrane transport+++GO:0070528///protein kinase C signaling+++GO:0070633///transepithelial transport+++GO:0071320///cellular response to cAMP+++GO:0071332///cellular response to fructose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:2001150///positive regulation of dipeptide transmembrane transport 171463 171463 'Il17rd' mRNA 663 629 565 4.24 3.95 3.85 3.16 2.6 3.2 4.013333333 2.986666667 567 458 556 619 527 0.055415294 -0.243248619 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030368///interleukin-17 receptor activity GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway 171469 171469 'Gpr37l1' mRNA 922 882 967 23.02 21.68 25.61 19.62 19.12 16.86 23.43666667 18.53333333 904 860 752 923.6666667 838.6666667 0.204633441 -0.154257845 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0060170///ciliary membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0036505///prosaposin receptor activity+++GO:0042277///peptide binding GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0021940///positive regulation of cerebellar granule cell precursor proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045665///negative regulation of neuron differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048712///negative regulation of astrocyte differentiation+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 17147 17147 'Mageb3' mRNA 5.18 2.05 4.18 0.13 0.05 0.11 0 0 0.09 0.096666667 0.03 0 0 4 3.803333333 1.333333333 0.484651252 -1.472466706 GO:0005634///nucleus GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 171486 171486 'Cd99l2' mRNA 1701 1821 1606 25.74 27.09 25.79 26.89 25.42 26.66 26.20666667 26.32333333 2044 1887 1960 1709.333333 1963.666667 0.010827719 0.189321907 04514///Cell adhesion molecules+++04670///Leukocyte transendothelial migration GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0007155///cell adhesion+++GO:0034109///homotypic cell-cell adhesion+++GO:0050904///diapedesis+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000409///positive regulation of T cell extravasation 17149 17149 'Magoh' mRNA 428 377 387 44.4 38.84 42.61 57.18 51.59 52.31 41.95 53.69333333 630 553 556 397.3333333 579.6666667 1.64E-05 0.531893061 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0007292///female gamete generation+++GO:0008380///RNA splicing+++GO:0051028///mRNA transport" 17150 17150 'Mfap2' mRNA 221 205 189 13.58 12.54 12.41 20.01 21.19 19.85 12.84333333 20.35 372 378 356 205 368.6666667 1.86E-08 0.836674252 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0070051///fibrinogen binding GO:0030220///platelet formation+++GO:0048048///embryonic eye morphogenesis+++GO:0048050///post-embryonic eye morphogenesis+++GO:0120162///positive regulation of cold-induced thermogenesis 171504 171504 'Apobr' mRNA 111 151 118 1.89 2.45 2.18 5 4.24 4.13 2.173333333 4.456666667 346 274.75 276 126.6666667 298.9166667 5.48E-11 1.225872371 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0042627///chylomicron GO:0030228///lipoprotein particle receptor activity+++GO:0030229///very-low-density lipoprotein particle receptor activity GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process 171506 171506 'H1f8' mRNA 0 0 1 0 0 0.06 0 0.1 0.05 0.02 0.05 0 2 1 0.333333333 1 0.726099345 1.486127565 GO:0000786///nucleosome+++GO:0001674///female germ cell nucleus+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0031492///nucleosomal DNA binding GO:0006334///nucleosome assembly+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0044030///regulation of DNA methylation+++GO:0045910///negative regulation of DNA recombination+++GO:0051321///meiotic cell cycle+++GO:2000737///negative regulation of stem cell differentiation 171508 171508 'Creld1' mRNA 1393 1406 1459 34.79 34.58 38.66 21.26 19.35 20.46 36.01 20.35666667 979 870 912 1419.333333 920.3333333 6.46E-13 -0.639403329 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003756///protein disulfide isomerase activity+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0016853///isomerase activity GO:0008150///biological_process 17151 17151 'Ccndbp1' mRNA 1209 1273 1150 45.16 46.87 45.55 39.04 38.83 38.97 45.86 38.94666667 1201 1166 1160 1210.666667 1175.666667 0.608760844 -0.053123526 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle 17152 17152 'Mak' mRNA 283 326 304 4.34 4.85 4.89 0.83 0.59 0.99 4.693333333 0.803333333 62 45 72 304.3333333 59.66666667 1.67E-29 -2.363916596 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030496///midbody+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection+++GO:0072686///mitotic spindle+++GO:0097542///ciliary tip GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042073///intraciliary transport+++GO:0045494///photoreceptor cell maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060271///cilium assembly+++GO:1902856///negative regulation of non-motile cilium assembly" 17153 17153 'Mal' mRNA 4165 4538 4447 82.82 88.82 93.8 60.05 56.78 57.32 88.48 58.05 3474 3208 3211 4383.333333 3297.666667 3.89E-10 -0.424242468 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0120003///hinge region between urothelial plaques of apical plasma membrane GO:0019911///structural constituent of myelin sheath GO:0002175///protein localization to paranode region of axon+++GO:0022010///central nervous system myelination+++GO:0042552///myelination+++GO:0098737///protein insertion into plasma membrane+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 171530 171530 'Ucn2' mRNA 4 1 3 0.26 0.06 0.2 0.89 0.29 0.4 0.173333333 0.526666667 16 5 7 2.666666667 9.333333333 0.135703374 1.779382073 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0051429///corticotropin-releasing hormone receptor binding+++GO:0051431///corticotropin-releasing hormone receptor 2 binding GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007586///digestion+++GO:0008283///cell proliferation+++GO:0009755///hormone-mediated signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0031669///cellular response to nutrient levels+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0046882///negative regulation of follicle-stimulating hormone secretion 171531 171531 'Mlph' mRNA 227.22 205 195.9 2.92 2.65 2.9 2.05 1.68 1.3 2.823333333 1.676666667 158 130 121 209.3733333 136.3333333 0.001639512 -0.628643184 GO:0001725///stress fiber+++GO:0005815///microtubule organizing center+++GO:0015629///actin cytoskeleton+++GO:0016461///unconventional myosin complex+++GO:0030425///dendrite+++GO:0030864///cortical actin cytoskeleton+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding+++GO:0031489///myosin V binding+++GO:0046872///metal ion binding+++GO:0051010///microtubule plus-end binding" GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0030318///melanocyte differentiation+++GO:0032400///melanosome localization+++GO:0043473///pigmentation 171543 171543 'Bmf' mRNA 108 99 115 1.24 1.12 1.39 1.53 1.54 1.44 1.25 1.503333333 153 150 139 107.3333333 147.3333333 0.062875354 0.442214851 05206///MicroRNAs in cancer GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0009267///cellular response to starvation+++GO:0010507///negative regulation of autophagy+++GO:0031334///positive regulation of protein complex assembly+++GO:0034644///cellular response to UV+++GO:0043065///positive regulation of apoptotic process+++GO:0043276///anoikis+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1904093///negative regulation of autophagic cell death+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001235///positive regulation of apoptotic signaling pathway 17155 17155 'Man1a' mRNA 217 235 117 2.32 2.54 1.31 3.97 4.23 4.47 2.056666667 4.223333333 430 449 472 189.6666667 450.3333333 5.30E-11 1.248599199 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0008152///metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0045047///protein targeting to ER+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway 17156 17156 'Man1a2' mRNA 1989 2095 2057 13.18 13.64 14.45 8.5 7.81 8.04 13.75666667 8.116666667 1477 1327 1354 2047 1386 6.36E-14 -0.576054755 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0007585///respiratory gaseous exchange+++GO:0008152///metabolic process+++GO:0009100///glycoprotein metabolic process+++GO:0048286///lung alveolus development 171567 171567 'Nme7' mRNA 372.43 430.75 320.02 12.24 14.09 11.2 9.15 8 9.76 12.51 8.97 318.84 271.21 327.84 374.4 305.9633333 0.059487603 -0.300768636 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005576///extracellular region+++GO:0005813///centrosome+++GO:0036064///ciliary basal body GO:0000166///nucleotide binding+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0003351///epithelial cilium movement+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0009117///nucleotide metabolic process+++GO:0016310///phosphorylation+++GO:0042073///intraciliary transport+++GO:0060830///ciliary receptor clustering involved in smoothened signaling pathway+++GO:0060972///left/right pattern formation+++GO:1990830///cellular response to leukemia inhibitory factor 17158 17158 'Man2a1' mRNA 246 214 162 2.14 1.84 1.5 5.52 5.4 5.43 1.826666667 5.45 729 696 694 207.3333333 706.3333333 1.79E-38 1.761544264 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0004559///alpha-mannosidase activity+++GO:0004572///mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity+++GO:0015923///mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0006517///protein deglycosylation+++GO:0007005///mitochondrion organization+++GO:0007033///vacuole organization+++GO:0007585///respiratory gaseous exchange+++GO:0008152///metabolic process+++GO:0048286///lung alveolus development+++GO:0050769///positive regulation of neurogenesis+++GO:0060042///retina morphogenesis in camera-type eye 171580 171580 'Mical1' mRNA 560 611 606 8.58 9.33 9.84 10.53 10.52 11.29 9.25 10.78 784 764 820 592.3333333 789.3333333 2.22E-04 0.401389247 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:1990026///hippocampal mossy fiber expansion "GO:0003779///actin binding+++GO:0004497///monooxygenase activity+++GO:0005515///protein binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0071949///FAD binding" GO:0001933///negative regulation of protein phosphorylation+++GO:0019417///sulfur oxidation+++GO:0030042///actin filament depolymerization+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1903305///regulation of regulated secretory pathway 17159 17159 'Man2b1' mRNA 1001 1147 1115 13.65 15.29 16.28 65.65 63.36 62.36 15.07333333 63.79 5449 5108 4995 1087.666667 5184 7.77E-207 2.239451639 00511///Other glycan degradation+++04142///Lysosome GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005774///vacuolar membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004559///alpha-mannosidase activity+++GO:0005537///mannose binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0006464///cellular protein modification process+++GO:0007611///learning or memory+++GO:0008152///metabolic process 17160 17160 'Man2b2' mRNA 2050 2118 2038 32.49 33.02 34.26 39.68 38.27 39.02 33.25666667 38.99 2881 2714 2744 2068.666667 2779.666667 3.00E-10 0.413877003 00511///Other glycan degradation GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005774///vacuolar membrane "GO:0003824///catalytic activity+++GO:0004559///alpha-mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0008152///metabolic process 17161 17161 'Maoa' mRNA 469.04 536.8 445.19 6.07 6.84 6.11 8.31 8.73 7.78 6.34 8.273333333 739.17 757.85 670.25 483.6766667 722.4233333 5.36E-07 0.569617568 "00260///Glycine, serine and threonine metabolism+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism" GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008131///primary amine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051378///serotonin binding+++GO:0097621///monoamine oxidase activity GO:0006584///catecholamine metabolic process+++GO:0009967///positive regulation of signal transduction+++GO:0042135///neurotransmitter catabolic process+++GO:0042420///dopamine catabolic process+++GO:0042428///serotonin metabolic process+++GO:0042443///phenylethylamine metabolic process 17164 17164 'Mapkapk2' mRNA 491 528 465 9.42 9.97 9.47 18.72 18.48 18.95 9.62 18.71666667 1122 1082 1100 494.6666667 1101.333333 1.51E-34 1.14425256 04010///MAPK signaling pathway+++04218///Cellular senescence+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04625///C-type lectin receptor signaling pathway+++04722///Neurotrophin signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005813///centrosome+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035091///phosphatidylinositol binding+++GO:0051019///mitogen-activated protein kinase binding GO:0002224///toll-like receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034097///response to cytokine+++GO:0035556///intracellular signal transduction+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038066///p38MAPK cascade+++GO:0044351///macropinocytosis+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048255///mRNA stabilization+++GO:0048839///inner ear development+++GO:0070935///3'-UTR-mediated mRNA stabilization 17165 17165 'Mapkapk5' mRNA 401 411 343 10.23 10.33 9.29 7.95 8.07 7.98 9.95 8 358 355 348 385 353.6666667 0.404096278 -0.131333947 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032156///septin cytoskeleton+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation+++GO:0051973///positive regulation of telomerase activity+++GO:0060999///positive regulation of dendritic spine development+++GO:0090400///stress-induced premature senescence+++GO:1904355///positive regulation of telomere capping 17167 17167 'Marco' mRNA 0 1 0 0 0.03 0 2.66 2.67 2.3 0.01 2.543333333 103 101 86 0.333333333 96.66666667 1.62E-10 8.06370899 04145///Phagosome GO:0005581///collagen trimer+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding+++GO:0001664///G protein-coupled receptor binding+++GO:0005044///scavenger receptor activity+++GO:0038024///cargo receptor activity "GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0043277///apoptotic cell clearance+++GO:0045087///innate immune response+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097242///amyloid-beta clearance" 17168 17168 'Nprl3' mRNA 820.98 770.46 804.29 15.87 14.68 16.44 12.67 12.54 10.74 15.66333333 11.98333333 758.48 733.08 622.64 798.5766667 704.7333333 0.109997093 -0.19364037 04150///mTOR signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:1990130///GATOR1 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0050692///DBD domain binding+++GO:0050693///LBD domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001709///cell fate determination+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0002088///lens development in camera-type eye+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0002194///hepatocyte cell migration+++GO:0003281///ventricular septum development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010595///positive regulation of endothelial cell migration+++GO:0021542///dentate gyrus development+++GO:0021707///cerebellar granule cell differentiation+++GO:0030240///skeletal muscle thin filament assembly+++GO:0030324///lung development+++GO:0031016///pancreas development+++GO:0031667///response to nutrient levels+++GO:0032007///negative regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0035909///aorta morphogenesis+++GO:0038202///TORC1 signaling+++GO:0042752///regulation of circadian rhythm+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045071///negative regulation of viral genome replication+++GO:0045446///endothelial cell differentiation+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046619///optic placode formation involved in camera-type eye formation+++GO:0048511///rhythmic process+++GO:0048738///cardiac muscle tissue development+++GO:0048839///inner ear development+++GO:0048845///venous blood vessel morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0055005///ventricular cardiac myofibril assembly+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060021///roof of mouth development+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060214///endocardium formation+++GO:0060298///positive regulation of sarcomere organization+++GO:0060412///ventricular septum morphogenesis+++GO:0060414///aorta smooth muscle tissue morphogenesis+++GO:0060421///positive regulation of heart growth+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0061114///branching involved in pancreas morphogenesis+++GO:0070309///lens fiber cell morphogenesis+++GO:0070365///hepatocyte differentiation+++GO:0070858///negative regulation of bile acid biosynthetic process+++GO:0072574///hepatocyte proliferation+++GO:0090425///acinar cell differentiation+++GO:0097150///neuronal stem cell population maintenance+++GO:1901978///positive regulation of cell cycle checkpoint+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000785///regulation of autophagosome assembly+++GO:2000979///positive regulation of forebrain neuron differentiation" 17169 17169 'Mark3' mRNA 465 475 436 7.96 8.09 8.13 6.63 7.21 8.62 8.06 7.486666667 451 453 545 458.6666667 483 0.712413939 0.064379226 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032092///positive regulation of protein binding+++GO:0035331///negative regulation of hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0036289///peptidyl-serine autophosphorylation 17171 17171 'Mas1' mRNA 67 74.99 56.96 0.78 0.92 0.75 0.42 0.57 0.29 0.816666667 0.426666667 39 42 26 66.31666667 35.66666667 0.017426387 -0.887936891 04080///Neuroactive ligand-receptor interaction+++04614///Renin-angiotensin system+++05171///Coronavirus disease - COVID-19 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001595///angiotensin receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0042277///peptide binding GO:0001933///negative regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007283///spermatogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0014823///response to activity+++GO:0021766///hippocampus development+++GO:0034698///response to gonadotropin+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042493///response to drug+++GO:0043434///response to peptide hormone+++GO:0045740///positive regulation of DNA replication+++GO:0050727///regulation of inflammatory response+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0070528///protein kinase C signaling+++GO:0071375///cellular response to peptide hormone stimulus 17172 17172 'Ascl1' mRNA 2 1 3 0.04 0.02 0.07 0.04 0.06 0.04 0.043333333 0.046666667 2 3 2 2 2.333333333 0.925378021 0.197698147 GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0003358///noradrenergic neuron development+++GO:0003359///noradrenergic neuron fate commitment+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007400///neuroblast fate determination+++GO:0007405///neuroblast proliferation+++GO:0007423///sensory organ development+++GO:0007507///heart development+++GO:0008593///regulation of Notch signaling pathway+++GO:0010001///glial cell differentiation+++GO:0010226///response to lithium ion+++GO:0010468///regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0021527///spinal cord association neuron differentiation+++GO:0021529///spinal cord oligodendrocyte cell differentiation+++GO:0021530///spinal cord oligodendrocyte cell fate specification+++GO:0021750///vestibular nucleus development+++GO:0021779///oligodendrocyte cell fate commitment+++GO:0021879///forebrain neuron differentiation+++GO:0021892///cerebral cortex GABAergic interneuron differentiation+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0032526///response to retinoic acid+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048484///enteric nervous system development+++GO:0048485///sympathetic nervous system development+++GO:0048486///parasympathetic nervous system development+++GO:0048663///neuron fate commitment+++GO:0048665///neuron fate specification+++GO:0048666///neuron development+++GO:0048699///generation of neurons+++GO:0048709///oligodendrocyte differentiation+++GO:0050767///regulation of neurogenesis+++GO:0050769///positive regulation of neurogenesis+++GO:0050883///musculoskeletal movement, spinal reflex action+++GO:0051593///response to folic acid+++GO:0060163///subpallium neuron fate commitment+++GO:0060165///regulation of timing of subpallium neuron differentiation+++GO:0060166///olfactory pit development+++GO:0060579///ventral spinal cord interneuron fate commitment+++GO:0061100///lung neuroendocrine cell differentiation+++GO:0061102///stomach neuroendocrine cell differentiation+++GO:0061103///carotid body glomus cell differentiation+++GO:0061104///adrenal chromaffin cell differentiation+++GO:0061549///sympathetic ganglion development+++GO:0070849///response to epidermal growth factor+++GO:0071259///cellular response to magnetism+++GO:2000179///positive regulation of neural precursor cell proliferation" 17173 17173 'Ascl2' mRNA 8 8 8 0.29 0.29 0.31 1.2 1.46 1.14 0.296666667 1.266666667 38 45 35 8 39.33333333 3.12E-05 2.287271762 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007423///sensory organ development+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050767///regulation of neurogenesis+++GO:0060708///spongiotrophoblast differentiation+++GO:0060712///spongiotrophoblast layer development 17174 17174 'Masp1' mRNA 425 436 499 5.81 5.86 7.26 3.19 3.12 2.45 6.31 2.92 268 255 198 453.3333333 240.3333333 7.18E-09 -0.932440731 04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0045087///innate immune response+++GO:0045916///negative regulation of complement activation" 17175 17175 'Masp2' mRNA 22.68 24.25 14.99 1 1.18 0.5 0.31 0.42 0.78 0.893333333 0.503333333 8.5 15.01 12.31 20.64 11.94 0.278911206 -0.775706383 04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001855///complement component C4b binding+++GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response" 17178 17178 'Fxyd3' mRNA 1957.15 1951.96 1932.38 307.4 306.27 322.23 248.9 266.93 260.53 311.9666667 258.7866667 1803.54 1877.41 1816.92 1947.163333 1832.623333 0.243279646 -0.099430742 GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017080///sodium channel regulator activity+++GO:0051117///ATPase binding+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0043269///regulation of ion transport+++GO:0050790///regulation of catalytic activity+++GO:2000649///regulation of sodium ion transmembrane transporter activity 17179 17179 'Matk' mRNA 202 186 186 6.18 5.55 6.04 4.92 4.57 3.98 5.923333333 4.49 182 166 144 191.3333333 164 0.281302745 -0.235105597 04722///Neurotrophin signaling pathway GO:0005737///cytoplasm+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation 17180 17180 'Matn1' mRNA 11 5 6 0.31 0.14 0.18 0.22 0.28 0.46 0.21 0.32 9 11 18 7.333333333 12.66666667 0.405539319 0.782036497 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0002062///chondrocyte differentiation+++GO:0003429///growth plate cartilage chondrocyte morphogenesis+++GO:0030500///regulation of bone mineralization 17181 17181 'Matn2' mRNA 812 864 957 12.41 13.02 15.5 23.69 24.42 23.57 13.64333333 23.89333333 1780 1793 1713 877.6666667 1762 4.49E-25 0.99023467 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0001764///neuron migration+++GO:0007411///axon guidance+++GO:0008347///glial cell migration+++GO:0031104///dendrite regeneration+++GO:0031175///neuron projection development+++GO:0048678///response to axon injury 17182 17182 'Matn3' mRNA 0 0 1 0 0 0.02 0.03 0.18 0.03 0.006666667 0.08 2 11 2 0.333333333 5 0.065010109 3.805180099 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding GO:0051216///cartilage development 17183 17183 'Matn4' mRNA 581 569 466 12.9 12.53 11.31 12.13 13.5 14.34 12.24666667 13.32333333 603 656 706 538.6666667 655 0.029596826 0.275108016 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0048678///response to axon injury 17184 17184 'Matr3' mRNA 3937 4244 4284 47.26 50.1 54.55 39.67 36.69 38.98 50.63666667 38.44666667 3804 3437 3620 4155 3620.333333 0.00391216 -0.213168116 05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0035198///miRNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001825///blastocyst formation+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0003170///heart valve development+++GO:0003281///ventricular septum development+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045087///innate immune response 17187 17187 'Max' mRNA 130 110 108 4.01 3.22 3.51 4.55 4.65 3.65 3.58 4.283333333 172 163 128 116 154.3333333 0.098253202 0.400388692 04010///MAPK signaling pathway+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05222///Small cell lung cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0030425///dendrite+++GO:0032993///protein-DNA complex+++GO:0042995///cell projection+++GO:0071339///MLL1 complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009267///cellular response to starvation+++GO:0010243///response to organonitrogen compound+++GO:0010629///negative regulation of gene expression+++GO:0032868///response to insulin+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048678///response to axon injury+++GO:0051402///neuron apoptotic process+++GO:0060041///retina development in camera-type eye+++GO:0065003///protein-containing complex assembly+++GO:0071375///cellular response to peptide hormone stimulus" 17188 17188 'Maz' mRNA 1082 962 560 24.75 21.59 13.81 16 18.02 19.77 20.05 17.93 785 864 935 868 861.3333333 0.987658866 -0.008752309 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006369///termination of RNA polymerase II transcription+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030335///positive regulation of cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051897///positive regulation of protein kinase B signaling+++GO:2001234///negative regulation of apoptotic signaling pathway" 17189 17189 'Mb' mRNA 30 45 31 1.87 2.66 2.19 0.99 0.66 1.08 2.24 0.91 18 12 18 35.33333333 16 0.027639214 -1.152263065 GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0007507///heart development+++GO:0009725///response to hormone+++GO:0015671///oxygen transport+++GO:0031444///slow-twitch skeletal muscle fiber contraction+++GO:0042542///response to hydrogen peroxide+++GO:0043353///enucleate erythrocyte differentiation+++GO:0050873///brown fat cell differentiation 17190 17190 'Mbd1' mRNA 1116 1259 1007 14.88 16 13.85 22.86 19.66 20.79 14.91 21.10333333 2000.01 1716 1799.37 1127.333333 1838.46 1.82E-16 0.695665728 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding GO:0010629///negative regulation of gene expression+++GO:0048712///negative regulation of astrocyte differentiation 17191 17191 'Mbd2' mRNA 300 296 301 9.37 9.2 9.93 9.8 11.18 10.83 9.5 10.60333333 362 403 385 299 383.3333333 0.019735043 0.346900699 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016581///NuRD complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008327///methyl-CpG binding+++GO:0019904///protein domain specific binding+++GO:0035197///siRNA binding+++GO:0070742///C2H2 zinc finger domain binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006346///methylation-dependent chromatin silencing+++GO:0007507///heart development+++GO:0007568///aging+++GO:0009612///response to mechanical stimulus+++GO:0014070///response to organic cyclic compound+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0034622///cellular protein-containing complex assembly+++GO:0035563///positive regulation of chromatin binding+++GO:0042127///regulation of cell proliferation+++GO:0042711///maternal behavior+++GO:0044030///regulation of DNA methylation+++GO:0048568///embryonic organ development+++GO:0071407///cellular response to organic cyclic compound 17192 17192 'Mbd3' mRNA 664 612 411 24.98 22.66 16.45 18.66 22.6 18.95 21.36333333 20.07 567 674 560 562.3333333 600.3333333 0.635788069 0.092699431 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016581///NuRD complex+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008327///methyl-CpG binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006346///methylation-dependent chromatin silencing+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007568///aging+++GO:0009888///tissue development+++GO:0014070///response to organic cyclic compound+++GO:0016573///histone acetylation+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0044030///regulation of DNA methylation+++GO:0048568///embryonic organ development 17193 17193 'Mbd4' mRNA 608.56 618.52 734.47 9.49 9.54 12.41 4.14 4.18 4.11 10.48 4.143333333 304.35 302.46 286.63 653.85 297.8133333 4.59E-17 -1.152753244 03410///Base excision repair GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016592///mediator complex+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008263///pyrimidine-specific mismatch base pair DNA N-glycosylase activity+++GO:0016787///hydrolase activity+++GO:0016922///nuclear receptor binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0050693///LBD domain binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0002088///lens development in camera-type eye+++GO:0002154///thyroid hormone mediated signaling pathway+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003406///retinal pigment epithelium development+++GO:0006281///DNA repair+++GO:0006306///DNA methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006590///thyroid hormone generation+++GO:0006606///protein import into nucleus+++GO:0006702///androgen biosynthetic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009314///response to radiation+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016567///protein ubiquitination+++GO:0030216///keratinocyte differentiation+++GO:0030224///monocyte differentiation+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0031100///animal organ regeneration+++GO:0032355///response to estradiol+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0035050///embryonic heart tube development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035162///embryonic hemopoiesis+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035855///megakaryocyte development+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048821///erythrocyte development+++GO:0048822///enucleate erythrocyte development+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060745///mammary gland branching involved in pregnancy+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation+++GO:0070318///positive regulation of G0 to G1 transition+++GO:0070562///regulation of vitamin D receptor signaling pathway+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2001141///regulation of RNA biosynthetic process" 17194 17194 'Mbl1' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04145///Phagosome+++04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005771///multivesicular body+++GO:0005791///rough endoplasmic reticulum GO:0002020///protease binding+++GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0070492///oligosaccharide binding+++GO:0120153///calcium-dependent carbohydrate binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0043129///surfactant homeostasis+++GO:0045087///innate immune response+++GO:0050766///positive regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051873///killing by host of symbiont cells+++GO:0070207///protein homotrimerization" 17195 17195 'Mbl2' mRNA 1 0 0 0.06 0 0 0 0 0.06 0.02 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04145///Phagosome+++04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005534///galactose binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0048306///calcium-dependent protein binding+++GO:0070273///phosphatidylinositol-4-phosphate binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0048525///negative regulation of viral process+++GO:0050766///positive regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051873///killing by host of symbiont cells" 17196 17196 'Mbp' mRNA 26650 27190 26952 707.18 710.12 758.39 397.16 425.21 382.99 725.23 401.7866667 17605 18318 16637 26930.66667 17520 1.93E-27 -0.632651627 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043218///compact myelin+++GO:0071944///cell periphery GO:0002020///protease binding+++GO:0005516///calmodulin binding+++GO:0019911///structural constituent of myelin sheath GO:0000165///MAPK cascade+++GO:0007605///sensory perception of sound+++GO:0009636///response to toxic substance+++GO:0032570///response to progesterone+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042552///myelination+++GO:0050771///negative regulation of axonogenesis+++GO:0061024///membrane organization+++GO:1904685///positive regulation of metalloendopeptidase activity+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 17199 17199 'Mc1r' mRNA 1 3 2.01 0.01 0.04 0.03 0.24 0.13 0.13 0.026666667 0.166666667 19 10 10 2.003333333 13 0.012114033 2.683941469 04080///Neuroactive ligand-receptor interaction+++04916///Melanogenesis GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004977///melanocortin receptor activity+++GO:0004980///melanocyte-stimulating hormone receptor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042562///hormone binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0019222///regulation of metabolic process+++GO:0019233///sensory perception of pain+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060259///regulation of feeding behavior+++GO:0070914///UV-damage excision repair+++GO:0090037///positive regulation of protein kinase C signaling+++GO:2000253///positive regulation of feeding behavior 17200 17200 'Mc2r' mRNA 2 2 0 0.07 0.07 0 0.22 0.06 0.13 0.046666667 0.136666667 7 2 4 1.333333333 4.333333333 0.347520166 1.702541483 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004977///melanocortin receptor activity+++GO:0004978///corticotropin receptor activity GO:0001890///placenta development+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0019222///regulation of metabolic process 17203 17203 'Mc5r' mRNA 10 3 4 0.14 0.04 0.06 0.24 0.28 0.44 0.08 0.32 20 23 36 5.666666667 26.33333333 0.002138369 2.210853052 04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004977///melanocortin receptor activity+++GO:0042562///hormone binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process 17207 17207 'Mcf2l' mRNA 1897 2063 1972 19.42 20.83 21.38 7.06 5.91 7.02 20.54333333 6.663333333 792 653 771 1977.333333 738.6666667 6.09E-59 -1.434108047 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030027///lamellipodium+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding GO:0007266///Rho protein signal transduction+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity 17210 17210 'Mcl1' mRNA 697 705 607 10.61 10.59 9.86 29.37 26.64 30.16 10.35333333 28.72333333 2192 1937 2184 669.6666667 2104.333333 6.90E-89 1.641570395 04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04630///JAK-STAT signaling pathway+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097136///Bcl-2 family protein complex GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0051400///BH domain binding+++GO:0051434///BH3 domain binding GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008637///apoptotic mitochondrial changes+++GO:0010507///negative regulation of autophagy+++GO:0030154///cell differentiation+++GO:0034097///response to cytokine+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1903378///positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:2000811///negative regulation of anoikis+++GO:2001020///regulation of response to DNA damage stimulus+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 17215 17215 'Mcm3' mRNA 155 132 163 2.91 2.47 3.27 16.4 15.31 15.73 2.883333333 15.81333333 998 919 938 150 951.6666667 4.25E-95 2.650844171 03030///DNA replication+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0042555///MCM complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006270///DNA replication initiation+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:1902975///mitotic DNA replication initiation 17216 17216 'Mcm2' mRNA 211 215 204 3.41 3.42 3.5 10.07 10.24 11.48 3.443333333 10.59666667 717 712 791 210 740 2.19E-48 1.806204945 03030///DNA replication+++04110///Cell cycle GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0042555///MCM complex+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0043138///3'-5' DNA helicase activity+++GO:0046872///metal ion binding GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0006334///nucleosome assembly+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:0071353///cellular response to interleukin-4+++GO:0090102///cochlea development+++GO:1902975///mitotic DNA replication initiation+++GO:1905775///negative regulation of DNA helicase activity 17217 17217 'Mcm4' mRNA 455 505 472 6.88 7.52 7.58 11.46 11.55 11.69 7.326666667 11.56666667 872 858 861 477.3333333 863.6666667 1.96E-16 0.843815617 03030///DNA replication+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0042555///MCM complex+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:1902975///mitotic DNA replication initiation 17218 17218 'Mcm5' mRNA 115 145 151 1.82 2.26 2.53 10.5 10.89 10.08 2.203333333 10.49 763 770 710 137 747.6666667 6.51E-66 2.434463847 03030///DNA replication+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042555///MCM complex+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0043138///3'-5' DNA helicase activity GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006270///DNA replication initiation+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding 17219 17219 'Mcm6' mRNA 315 324 298 5.4 5.59 5.58 23.05 23.16 20.13 5.523333333 22.11333333 1454 1434 1243 312.3333333 1377 1.99E-94 2.129285181 03030///DNA replication+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0042555///MCM complex+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0042802///identical protein binding+++GO:1990518///single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:1902969///mitotic DNA replication 17220 17220 'Mcm7' mRNA 588 557 580 13.01 12.37 14.06 23.38 22.84 20.59 13.14666667 22.27 1173 1122 1002 575 1099 8.71E-20 0.92123692 03030///DNA replication+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0042555///MCM complex+++GO:0071162///CMG complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0032508///DNA duplex unwinding+++GO:0042325///regulation of phosphorylation+++GO:0042493///response to drug+++GO:0071310///cellular response to organic substance+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071466///cellular response to xenobiotic stimulus 17221 17221 'Cd46' mRNA 27 40 23 1.19 1.32 0.89 0.82 1.15 0.53 1.133333333 0.833333333 28 30 15 30 24.33333333 0.632304497 -0.30606191 04610///Complement and coagulation cascades+++05162///Measles GO:0001669///acrosomal vesicle+++GO:0002079///inner acrosomal membrane+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0004175///endopeptidase activity+++GO:0045296///cadherin binding "GO:0002456///T cell mediated immunity+++GO:0006508///proteolysis+++GO:0007338///single fertilization+++GO:0008593///regulation of Notch signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0032733///positive regulation of interleukin-10 production+++GO:0035581///sequestering of extracellular ligand from receptor+++GO:0042102///positive regulation of T cell proliferation+++GO:0043382///positive regulation of memory T cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045862///positive regulation of proteolysis+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0071636///positive regulation of transforming growth factor beta production" 17222 17222 'Anapc1' mRNA 1966 2041 1903 13.58 13.28 13.22 13 12.05 12.59 13.36 12.54666667 2204 1963 2048 1970 2071.666667 0.48450236 0.060447285 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex GO:0005515///protein binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 17227 17227 'Mcpt4' mRNA 1 2 1 0.06 0.13 0.07 0 0 0 0.086666667 0 0 0 0 1.333333333 0 0.437121753 -2.859116386 04614///Renin-angiotensin system+++05415///Diabetic cardiomyopathy GO:0005615///extracellular space+++GO:0005622///intracellular GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0002002///regulation of angiotensin levels in blood+++GO:0006508///proteolysis 17228 17228 'Cma1' mRNA 6 9 5 0.34 0.51 0.3 0.05 0.21 0.31 0.383333333 0.19 1 4 6 6.666666667 3.666666667 0.527819231 -0.858141561 04614///Renin-angiotensin system+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005829///cytosol+++GO:0030141///secretory granule+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0022617///extracellular matrix disassembly+++GO:0030901///midbrain development+++GO:0034769///basement membrane disassembly+++GO:0045766///positive regulation of angiogenesis+++GO:0050727///regulation of inflammatory response+++GO:0071333///cellular response to glucose stimulus 17229 17229 'Tpsb2' mRNA 11 8 18 0.63 0.46 1.1 0.46 0.29 0.36 0.73 0.37 9 5 7 12.33333333 7 0.366833219 -0.848912514 05164///Influenza A GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:0022617///extracellular matrix disassembly 17231 17231 'Mcpt8' mRNA 2 2 3 0.16 0.16 0.25 0.14 0.83 0.48 0.19 0.483333333 2 12 7 2.333333333 7 0.248266243 1.57807471 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 17235 17235 'Smcp' mRNA 2 0 0 0.14 0 0 0.12 0 0 0.046666667 0.04 2 0 0 0.666666667 0.666666667 0.998591786 -0.015958787 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0007341///penetration of zona pellucida+++GO:0030317///flagellated sperm motility 17237 17237 'Mgrn1' mRNA 4101 4101 4037 71.05 70.06 74.3 56.87 54.65 52.76 71.80333333 54.76 3780 3550 3383 4079.666667 3571 0.00189096 -0.205023567 04120///Ubiquitin mediated proteolysis+++04340///Hedgehog signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0008333///endosome to lysosome transport+++GO:0016567///protein ubiquitination+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045879///negative regulation of smoothened signaling pathway 17240 17240 'Mdfi' mRNA 73 76 34 2.75 2.81 1.29 2.13 2.21 2.76 2.283333333 2.366666667 68 68 84 61 73.33333333 0.524016169 0.268217238 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007257///activation of JUN kinase activity+++GO:0007275///multicellular organism development+++GO:0009950///dorsal/ventral axis specification+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0043392///negative regulation of DNA binding+++GO:0046328///regulation of JNK cascade+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0060707///trophoblast giant cell differentiation 17242 17242 'Mdk' mRNA 865 836 797 72.41 68.91 70.86 64.01 65.49 58.45 70.72666667 62.65 875 895 777 832.6666667 849 0.895902596 0.016949742 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0035374///chondroitin sulfate binding+++GO:1904399///heparan sulfate binding "GO:0001662///behavioral fear response+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002286///T cell activation involved in immune response+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0007010///cytoskeleton organization+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007614///short-term memory+++GO:0009611///response to wounding+++GO:0009725///response to hormone+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0010996///response to auditory stimulus+++GO:0016477///cell migration+++GO:0021542///dentate gyrus development+++GO:0021681///cerebellar granular layer development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0030421///defecation+++GO:0032330///regulation of chondrocyte differentiation+++GO:0032735///positive regulation of interleukin-12 production+++GO:0042246///tissue regeneration+++GO:0042493///response to drug+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044849///estrous cycle+++GO:0045582///positive regulation of T cell differentiation+++GO:0045590///negative regulation of regulatory T cell differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046850///regulation of bone remodeling+++GO:0048477///oogenesis+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0050795///regulation of behavior+++GO:0051384///response to glucocorticoid+++GO:0051781///positive regulation of cell division+++GO:0061036///positive regulation of cartilage development+++GO:0071673///positive regulation of smooth muscle cell chemotaxis+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0106015///negative regulation of inflammatory response to wounding+++GO:0106016///positive regulation of inflammatory response to wounding+++GO:0106091///glial cell projection elongation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901215///negative regulation of neuron death+++GO:1903039///positive regulation of leukocyte cell-cell adhesion+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1905555///positive regulation blood vessel branching+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1905653///positive regulation of artery morphogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2001224///positive regulation of neuron migration" 17245 17245 'Mdm1' mRNA 305 343 247 5.18 5.61 4.59 3.61 4.13 3.68 5.126666667 3.806666667 253 272 236 298.3333333 253.6666667 0.186057321 -0.239916917 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0097730///non-motile cilium GO:0008017///microtubule binding GO:0045494///photoreceptor cell maintenance+++GO:0046600///negative regulation of centriole replication+++GO:0060041///retina development in camera-type eye 17246 17246 'Mdm2' mRNA 1538.52 1542.11 1534.13 25 25.03 27.12 28.33 28.96 29.93 25.71666667 29.07333333 2048.15 1974.14 2033.68 1538.253333 2018.656667 2.49E-07 0.379573258 01522///Endocrine resistance+++01524///Platinum drug resistance+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04625///C-type lectin receptor signaling pathway+++04919///Thyroid hormone signaling pathway+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0002039///p53 binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0019789///SUMO transferase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033612///receptor serine/threonine kinase binding+++GO:0042802///identical protein binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0061663///NEDD8 ligase activity+++GO:0097718///disordered domain specific binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001974///blood vessel remodeling+++GO:0002027///regulation of heart rate+++GO:0003170///heart valve development+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0007507///heart development+++GO:0009636///response to toxic substance+++GO:0010039///response to iron ion+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010955///negative regulation of protein processing+++GO:0010977///negative regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0031648///protein destabilization+++GO:0032026///response to magnesium ion+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034504///protein localization to nucleus+++GO:0042176///regulation of protein catabolic process+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043278///response to morphine+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045184///establishment of protein localization+++GO:0045472///response to ether+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046677///response to antibiotic+++GO:0046827///positive regulation of protein export from nucleus+++GO:0048545///response to steroid hormone+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0051726///regulation of cell cycle+++GO:0051865///protein autoubiquitination+++GO:0060411///cardiac septum morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071236///cellular response to antibiotic+++GO:0071301///cellular response to vitamin B1+++GO:0071310///cellular response to organic substance+++GO:0071312///cellular response to alkaloid+++GO:0071363///cellular response to growth factor stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0071480///cellular response to gamma radiation+++GO:0071494///cellular response to UV-C+++GO:0072717///cellular response to actinomycin D+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1904404///response to formaldehyde+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1990000///amyloid fibril formation+++GO:1990785///response to water-immersion restraint stress" 17248 17248 'Mdm4' mRNA 1337 1521 1234 9.78 10.93 9.58 9.45 8.21 8.7 10.09666667 8.786666667 1488 1262 1328 1364 1359.333333 0.895584737 -0.015132513 04115///p53 signaling pathway+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002027///regulation of heart rate+++GO:0003170///heart valve development+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:0065003///protein-containing complex assembly+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071456///cellular response to hypoxia+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator" 17250 17250 'Abcc1' mRNA 727 735 738 5.88 5.96 6.18 6.24 5.17 5.95 6.006666667 5.786666667 857 693 806 733.3333333 785.3333333 0.525780942 0.084622957 01523///Antifolate resistance+++02010///ABC transporters+++04071///Sphingolipid signaling pathway+++04977///Vitamin digestion and absorption+++05206///MicroRNAs in cancer GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane "GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015420///cobalamin-transporting ATPase activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0034040///lipid-transporting ATPase activity+++GO:0034634///glutathione transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042887///amide transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0046943///carboxylic acid transmembrane transporter activity" GO:0006979///response to oxidative stress+++GO:0009235///cobalamin metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0030335///positive regulation of cell migration+++GO:0033700///phospholipid efflux+++GO:0034775///glutathione transmembrane transport+++GO:0042493///response to drug+++GO:0042908///xenobiotic transport+++GO:0045332///phospholipid translocation+++GO:0050729///positive regulation of inflammatory response+++GO:0055085///transmembrane transport+++GO:0060326///cell chemotaxis+++GO:0060548///negative regulation of cell death+++GO:0070633///transepithelial transport+++GO:0071716///leukotriene transport+++GO:0099039///sphingolipid translocation+++GO:0140115///export across plasma membrane+++GO:1901215///negative regulation of neuron death+++GO:1904646///cellular response to amyloid-beta+++GO:1905039///carboxylic acid transmembrane transport+++GO:1990961///drug transmembrane export+++GO:1990962///drug transport across blood-brain barrier 17252 17252 'Rdh11' mRNA 578 577 555 10.86 10.67 11.08 9.82 9.48 9.53 10.87 9.61 601 567 565 570 577.6666667 0.962761947 0.007317877 00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0001917///photoreceptor inner segment+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042622///photoreceptor outer segment membrane GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0033721///aldehyde dehydrogenase (NADP+) activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0102354///11-cis-retinol dehydrogenase activity GO:0001523///retinoid metabolic process+++GO:0007601///visual perception+++GO:0016062///adaptation of rhodopsin mediated signaling+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:0110095///cellular detoxification of aldehyde 17254 17254 'Slc3a2' mRNA 8777.37 8923.23 8983.22 240.97 243.7 262.56 339.9 367.48 353.4 249.0766667 353.5933333 13987.82 14740.94 14143.68 8894.606667 14290.81333 1.85E-29 0.671602654 04150///mTOR signaling pathway+++04216///Ferroptosis+++04974///Protein digestion and absorption GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0044225///apical pole of neuron+++GO:0045202///synapse+++GO:1990184///amino acid transport complex GO:0003725///double-stranded RNA binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0015173///aromatic amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015190///L-leucine transmembrane transporter activity GO:0005975///carbohydrate metabolic process+++GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015820///leucine transport+++GO:0015823///phenylalanine transport+++GO:0015827///tryptophan transport+++GO:0043330///response to exogenous dsRNA+++GO:0046718///viral entry into host cell+++GO:0098713///leucine import across plasma membrane+++GO:1903801///L-leucine import across plasma membrane+++GO:1904273///L-alanine import across plasma membrane 17256 17256 'Mea1' mRNA 1354.04 1391.35 1269.99 105.12 108.09 105.28 109.92 107.54 105.13 106.1633333 107.53 1628.77 1537.14 1487.94 1338.46 1551.283333 0.011887385 0.201653999 GO:0005737///cytoplasm GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 17257 17257 'Mecp2' mRNA 1049 1010 1064 5.23 4.94 5.62 4.34 3.67 4.26 5.263333333 4.09 1005 831 956 1041 930.6666667 0.106177296 -0.176446548 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0010369///chromocenter+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008327///methyl-CpG binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0035197///siRNA binding+++GO:0042826///histone deacetylase binding+++GO:0045322///unmethylated CpG binding+++GO:0047485///protein N-terminus binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001662///behavioral fear response+++GO:0001666///response to hypoxia+++GO:0001964///startle response+++GO:0001976///neurological system process involved in regulation of systemic arterial blood pressure+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006020///inositol metabolic process+++GO:0006342///chromatin silencing+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006541///glutamine metabolic process+++GO:0006576///cellular biogenic amine metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0007052///mitotic spindle organization+++GO:0007268///chemical synaptic transmission+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0007420///brain development+++GO:0007585///respiratory gaseous exchange+++GO:0007612///learning+++GO:0007613///memory+++GO:0007616///long-term memory+++GO:0008104///protein localization+++GO:0008211///glucocorticoid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016358///dendrite development+++GO:0016525///negative regulation of angiogenesis+++GO:0016571///histone methylation+++GO:0016573///histone acetylation+++GO:0019230///proprioception+++GO:0019233///sensory perception of pain+++GO:0021549///cerebellum development+++GO:0021591///ventricular system development+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0031507///heterochromatin assembly+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032048///cardiolipin metabolic process+++GO:0032091///negative regulation of protein binding+++GO:0033555///multicellular organismal response to stress+++GO:0035176///social behavior+++GO:0035865///cellular response to potassium ion+++GO:0040014///regulation of multicellular organism growth+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042220///response to cocaine+++GO:0042551///neuron maturation+++GO:0042593///glucose homeostasis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0044030///regulation of DNA methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046470///phosphatidylcholine metabolic process+++GO:0048167///regulation of synaptic plasticity+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0050795///regulation of behavior+++GO:0050807///regulation of synapse organization+++GO:0050884///neuromuscular process controlling posture+++GO:0050905///neuromuscular process+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:0051570///regulation of histone H3-K9 methylation+++GO:0051707///response to other organism+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0060399///positive regulation of growth hormone receptor signaling pathway+++GO:0060999///positive regulation of dendritic spine development+++GO:0061000///negative regulation of dendritic spine development+++GO:0071317///cellular response to isoquinoline alkaloid+++GO:0090063///positive regulation of microtubule nucleation+++GO:0090327///negative regulation of locomotion involved in locomotory behavior+++GO:0099611///regulation of action potential firing threshold+++GO:1900114///positive regulation of histone H3-K9 trimethylation+++GO:1901953///positive regulation of anterograde dense core granule transport+++GO:1901956///positive regulation of retrograde dense core granule transport+++GO:1903860///negative regulation of dendrite extension+++GO:1903861///positive regulation of dendrite extension+++GO:1903941///negative regulation of respiratory gaseous exchange+++GO:1905492///positive regulation of branching morphogenesis of a nerve+++GO:1905643///positive regulation of DNA methylation+++GO:2000635///negative regulation of primary miRNA processing+++GO:2000820///negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation" 17258 17258 'Mef2a' mRNA 1183 1162 778 11.36 10.97 7.99 12.17 13.86 14.01 10.10666667 13.34666667 1456 1618 1623 1041 1565.666667 7.75E-07 0.586684984 "04013///MAPK signaling pathway - fly+++04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05418///Fluid shear stress and atherosclerosis" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0033613///activating transcription factor binding+++GO:0035035///histone acetyltransferase binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000002///mitochondrial genome maintenance+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0048311///mitochondrion distribution+++GO:0048813///dendrite morphogenesis+++GO:0055005///ventricular cardiac myofibril assembly+++GO:0061337///cardiac conduction+++GO:0070375///ERK5 cascade+++GO:0071277///cellular response to calcium ion" 17259 17259 'Mef2b' mRNA 34.54 19 26.35 1.57 0.85 1.27 0.94 1.19 1.03 1.23 1.053333333 23.85 29.34 25.17 26.63 26.12 0.941837331 -0.04866076 04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0030054///cell junction "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042826///histone deacetylase binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 17260 17260 'Mef2c' mRNA 509.2 533.12 429.04 2.73 2.49 2.24 6.94 6.33 6.73 2.486666667 6.666666667 1271.25 1084.78 1202.59 490.4533333 1186.206667 3.90E-37 1.26424755 "04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway+++04921///Oxytocin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05202///Transcriptional misregulation in cancer+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016528///sarcoplasm+++GO:0016607///nuclear speck+++GO:0030017///sarcomere+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098794///postsynapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0033613///activating transcription factor binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001568///blood vessel development+++GO:0001649///osteoblast differentiation+++GO:0001764///neuron migration+++GO:0001782///B cell homeostasis+++GO:0001947///heart looping+++GO:0001958///endochondral ossification+++GO:0001974///blood vessel remodeling+++GO:0002062///chondrocyte differentiation+++GO:0002467///germinal center formation+++GO:0002634///regulation of germinal center formation+++GO:0003138///primary heart field specification+++GO:0003139///secondary heart field specification+++GO:0003151///outflow tract morphogenesis+++GO:0003185///sinoatrial valve morphogenesis+++GO:0003211///cardiac ventricle formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006959///humoral immune response+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0007521///muscle cell fate determination+++GO:0007611///learning or memory+++GO:0010467///gene expression+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0014033///neural crest cell differentiation+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0014902///myotube differentiation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030220///platelet formation+++GO:0030224///monocyte differentiation+++GO:0030279///negative regulation of ossification+++GO:0030318///melanocyte differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0030890///positive regulation of B cell proliferation+++GO:0035050///embryonic heart tube development+++GO:0035690///cellular response to drug+++GO:0035914///skeletal muscle cell differentiation+++GO:0035984///cellular response to trichostatin A+++GO:0042100///B cell proliferation+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045165///cell fate commitment+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048167///regulation of synaptic plasticity+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0048666///neuron development+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050853///B cell receptor signaling pathway+++GO:0051145///smooth muscle cell differentiation+++GO:0051963///regulation of synapse assembly+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0055007///cardiac muscle cell differentiation+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060021///roof of mouth development+++GO:0060025///regulation of synaptic activity+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060079///excitatory postsynaptic potential+++GO:0060290///transdifferentiation+++GO:0060297///regulation of sarcomere organization+++GO:0060536///cartilage morphogenesis+++GO:0060998///regulation of dendritic spine development+++GO:0061333///renal tubule morphogenesis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071277///cellular response to calcium ion+++GO:0071300///cellular response to retinoic acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071498///cellular response to fluid shear stress+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0072102///glomerulus morphogenesis+++GO:0072160///nephron tubule epithelial cell differentiation+++GO:0097492///sympathetic neuron axon guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:1905563///negative regulation of vascular endothelial cell proliferation+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2000987///positive regulation of behavioral fear response+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis+++GO:2001016///positive regulation of skeletal muscle cell differentiation" 17261 17261 'Mef2d' mRNA 1672 1671 827 16.51 16.16 8.88 10.21 11.61 10.8 13.85 10.87333333 1164 1295 1199 1390 1219.333333 0.643490946 -0.184130987 "04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0033613///activating transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001649///osteoblast differentiation+++GO:0001958///endochondral ossification+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007512///adult heart development+++GO:0030154///cell differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation" 17268 17268 'Meis1' mRNA 897 855 939 17.37 16.04 18.53 8.3 8.04 8.53 17.31333333 8.29 505 479 503 897 495.6666667 7.47E-16 -0.870324576 04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0001525///angiogenesis+++GO:0001654///eye development+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007626///locomotory behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0030097///hemopoiesis+++GO:0035855///megakaryocyte development+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060216///definitive hemopoiesis" 17274 17274 'Rab8a' mRNA 1960 2245 2026 55.43 62.54 60.78 72.61 72.66 72.68 59.58333333 72.65 2952 2884 2860 2077 2898.666667 2.63E-11 0.46951212 04140///Autophagy - animal+++04144///Endocytosis+++04152///AMPK signaling pathway+++04530///Tight junction+++04972///Pancreatic secretion+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0097546///ciliary base+++GO:0097730///non-motile cilium+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0031489///myosin V binding "GO:0006904///vesicle docking involved in exocytosis+++GO:0006914///autophagy+++GO:0007409///axonogenesis+++GO:0009306///protein secretion+++GO:0010506///regulation of autophagy+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0030030///cell projection organization+++GO:0032869///cellular response to insulin stimulus+++GO:0032880///regulation of protein localization+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048210///Golgi vesicle fusion to target membrane+++GO:0051223///regulation of protein transport+++GO:0060271///cilium assembly+++GO:0072659///protein localization to plasma membrane+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0098969///neurotransmitter receptor transport to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse" 17279 17279 'Melk' mRNA 3 0 3 0.07 0 0.06 3.09 3.26 3.19 0.043333333 3.18 176 179 173 2 176 1.91E-23 6.447185831 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030097///hemopoiesis+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0061351///neural precursor cell proliferation 17281 17281 'Fyco1' mRNA 1441.96 1428.48 1338.5 9.71 9.45 9.57 8.36 7.2 8.15 9.576666667 7.903333333 1432.99 1204.43 1350.19 1402.98 1329.203333 0.359868266 -0.090106349 05132///Salmonella infection GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0046872///metal ion binding GO:0072383///plus-end-directed vesicle transport along microtubule+++GO:1901098///positive regulation of autophagosome maturation 17283 17283 'Men1' mRNA 1277 1237 1338 25.44 24.55 28.79 20.72 22.22 20.35 26.26 21.09666667 1193 1230 1123 1284 1182 0.205247044 -0.133315375 04934///Cushing syndrome+++05202///Transcriptional misregulation in cancer "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0035097///histone methyltransferase complex" "GO:0000400///four-way junction DNA binding+++GO:0000403///Y-form DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0043565///sequence-specific DNA binding+++GO:0047485///protein N-terminus binding+++GO:0051219///phosphoprotein binding+++GO:0070412///R-SMAD binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000278///mitotic cell cycle+++GO:0001503///ossification+++GO:0001776///leukocyte homeostasis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002051///osteoblast fate commitment+++GO:0002076///osteoblast development+++GO:0003309///type B pancreatic cell differentiation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007050///cell cycle arrest+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0009411///response to UV+++GO:0009790///embryo development+++GO:0010332///response to gamma radiation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0016571///histone methylation+++GO:0030097///hemopoiesis+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031062///positive regulation of histone methylation+++GO:0032092///positive regulation of protein binding+++GO:0032925///regulation of activin receptor signaling pathway+++GO:0034968///histone lysine methylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045597///positive regulation of cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0046621///negative regulation of organ growth+++GO:0046697///decidualization+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051568///histone H3-K4 methylation+++GO:0051781///positive regulation of cell division+++GO:0051974///negative regulation of telomerase activity+++GO:0060021///roof of mouth development+++GO:0060135///maternal process involved in female pregnancy+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0071333///cellular response to glucose stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071559///response to transforming growth factor beta+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 17285 17285 'Meox1' mRNA 3 1 4 0.08 0.03 0.11 0.42 0.64 0.3 0.073333333 0.453333333 19 28 13 2.666666667 20 0.001211398 2.888293379 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001757///somite specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060218///hematopoietic stem cell differentiation+++GO:0061053///somite development+++GO:0061056///sclerotome development" 17286 17286 'Meox2' mRNA 4 3 1 0.09 0.07 0.03 0.1 0.11 0.06 0.063333333 0.09 5 5 3 2.666666667 4.333333333 0.678833557 0.703715449 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001525///angiogenesis+++GO:0001757///somite specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007519///skeletal muscle tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060021///roof of mouth development+++GO:0060173///limb development+++GO:0061053///somite development+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis" 17287 17287 'Mep1a' mRNA 1 0 3 0.02 0 0.06 0.13 0.1 0.15 0.026666667 0.126666667 8 6 9 1.333333333 7.666666667 0.079521715 2.484755818 04974///Protein digestion and absorption GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017090///meprin A complex GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 17289 17289 'Mertk' mRNA 1832.76 1883.99 1821.54 20.15 20.47 21.32 23.77 21.76 22.58 20.64666667 22.70333333 2468.72 2217.64 2274.52 1846.096667 2320.293333 9.66E-06 0.31717529 GO:0001750///photoreceptor outer segment+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016028///rhabdomere+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001779///natural killer cell differentiation+++GO:0001818///negative regulation of cytokine production+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030168///platelet activation+++GO:0032940///secretion by cell+++GO:0033674///positive regulation of kinase activity+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043277///apoptotic cell clearance+++GO:0043491///protein kinase B signaling+++GO:0050766///positive regulation of phagocytosis+++GO:0051250///negative regulation of lymphocyte activation+++GO:0060041///retina development in camera-type eye+++GO:0060068///vagina development+++GO:0097350///neutrophil clearance+++GO:2000107///negative regulation of leukocyte apoptotic process 17293 17293 'Mesp2' mRNA 62 56 52 1.83 1.63 1.63 1.1 1.29 1.06 1.696666667 1.15 43 49 40 56.66666667 44 0.348405781 -0.374243109 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001707///mesoderm formation+++GO:0001756///somitogenesis+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0008078///mesodermal cell migration+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0032525///somite rostral/caudal axis specification+++GO:0045944///positive regulation of transcription by RNA polymerase II" 17294 17294 'Mest' mRNA 3086.56 3233.46 3009.41 47.12 50.89 51.8 68.77 70.39 71.04 49.93666667 70.06666667 4332.15 4232.15 4201.95 3109.81 4255.416667 2.46E-14 0.441170333 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0016787///hydrolase activity GO:0010883///regulation of lipid storage+++GO:0032526///response to retinoic acid 17295 17295 'Met' mRNA 383 387 326 3.08 3.21 2.78 2.9 2.49 2.52 3.023333333 2.636666667 418 353 351 365.3333333 374 0.895145002 0.023438621 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04360///Axon guidance+++04361///Axon regeneration+++04510///Focal adhesion+++04520///Adherens junction+++05100///Bacterial invasion of epithelial cells+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05144///Malaria+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma+++05218///Melanoma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0036126///sperm flagellum+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005008///hepatocyte growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017154///semaphorin receptor activity+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0001764///neuron migration+++GO:0001886///endothelial cell morphogenesis+++GO:0001889///liver development+++GO:0001890///placenta development+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0010976///positive regulation of neuron projection development+++GO:0014812///muscle cell migration+++GO:0014902///myotube differentiation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0030182///neuron differentiation+++GO:0030317///flagellated sperm motility+++GO:0030534///adult behavior+++GO:0031016///pancreas development+++GO:0031116///positive regulation of microtubule polymerization+++GO:0032675///regulation of interleukin-6 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0042593///glucose homeostasis+++GO:0043410///positive regulation of MAPK cascade+++GO:0045740///positive regulation of DNA replication+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050918///positive chemotaxis+++GO:0051450///myoblast proliferation+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060079///excitatory postsynaptic potential+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0061436///establishment of skin barrier+++GO:0070495///negative regulation of thrombin-activated receptor signaling pathway+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0071635///negative regulation of transforming growth factor beta production+++GO:0072593///reactive oxygen species metabolic process+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity+++GO:2001028///positive regulation of endothelial cell chemotaxis 17299 17299 'Mettl1' mRNA 152 155 130 10.3 10.32 8.48 17.21 16.03 14.83 9.7 16.02333333 301 280 255 145.6666667 278.6666667 9.42E-08 0.926002387 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0043527///tRNA methyltransferase complex GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008176///tRNA (guanine-N7-)-methyltransferase activity+++GO:0016740///transferase activity GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0036265///RNA (guanine-N7)-methylation+++GO:0106004///tRNA (guanine-N7)-methylation 17300 17300 'Foxc1' mRNA 341 356 283 4.61 4.74 4.06 6.16 5.85 6.38 4.47 6.13 524 486 526 326.6666667 512 5.85E-07 0.639759461 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0008301///DNA binding, bending+++GO:0043565///sequence-specific DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001568///blood vessel development+++GO:0001654///eye development+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001822///kidney development+++GO:0001945///lymph vessel development+++GO:0001958///endochondral ossification+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0008354///germ cell migration+++GO:0009653///anatomical structure morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0014031///mesenchymal cell development+++GO:0014032///neural crest cell development+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0021549///cerebellum development+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0030203///glycosaminoglycan metabolic process+++GO:0032808///lacrimal gland development+++GO:0035050///embryonic heart tube development+++GO:0036438///maintenance of lens transparency+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043010///camera-type eye development+++GO:0043388///positive regulation of DNA binding+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046620///regulation of organ growth+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048341///paraxial mesoderm formation+++GO:0048762///mesenchymal cell differentiation+++GO:0048844///artery morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060038///cardiac muscle cell proliferation+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072010///glomerular epithelium development+++GO:0097746///regulation of blood vessel diameter+++GO:1901491///negative regulation of lymphangiogenesis+++GO:1901534///positive regulation of hematopoietic progenitor cell differentiation+++GO:1902038///positive regulation of hematopoietic stem cell differentiation+++GO:1902257///negative regulation of apoptotic process involved in outflow tract morphogenesis+++GO:1904798///positive regulation of core promoter binding+++GO:1990869///cellular response to chemokine" 17301 17301 'Foxd2' mRNA 1 2 2 0.02 0.04 0.04 0.02 0.02 0.06 0.033333333 0.033333333 1 1 3 1.666666667 1.666666667 0.998591786 -0.014213146 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 17304 17304 'Mfge8' mRNA 768 751 711 21.56 20.8 21.2 48.47 48.89 50.72 21.18666667 49.36 1990 1964 2017 743.3333333 1990.333333 9.18E-75 1.409993125 GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0001786///phosphatidylserine binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0008429///phosphatidylethanolamine binding "GO:0001525///angiogenesis+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0043277///apoptotic cell clearance+++GO:0050766///positive regulation of phagocytosis" 17305 17305 'Mfng' mRNA 577 578 512 18.07 17.83 17.02 9.19 7.86 9.28 17.64 8.776666667 334 279 328 555.6666667 313.6666667 2.62E-11 -0.835904811 00514///Other types of O-glycan biosynthesis+++04330///Notch signaling pathway+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0005515///protein binding+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0033829///O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity+++GO:0046872///metal ion binding" GO:0001825///blastocyst formation+++GO:0002315///marginal zone B cell differentiation+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0008593///regulation of Notch signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0045747///positive regulation of Notch signaling pathway 17306 17306 'Sypl2' mRNA 50 54 44 0.84 0.89 0.79 0.07 0.1 0.03 0.84 0.066666667 5 7 2 49.33333333 4.666666667 7.61E-09 -3.409954346 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane GO:0017075///syntaxin-1 binding GO:0006874///cellular calcium ion homeostasis+++GO:0007507///heart development+++GO:0033292///T-tubule organization 17308 17308 'Mgat1' mRNA 1470 1508 1357 29.22 29.62 28.74 37.65 36.43 36.04 29.19333333 36.70666667 2119 2007 1967 1445 2031 1.01E-11 0.480322487 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0003827///alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding" GO:0001701///in utero embryonic development+++GO:0006049///UDP-N-acetylglucosamine catabolic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine 17309 17309 'Mgat3' mRNA 1509.94 1428.65 1443.64 14.2 13.26 14.95 8.25 7.61 8.97 14.13666667 8.276666667 1016.71 907.99 1079.81 1460.743333 1001.503333 6.89E-10 -0.557904649 00510///N-Glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003830///beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006044///N-acetylglucosamine metabolic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0008104///protein localization+++GO:0030334///regulation of cell migration+++GO:0034599///cellular response to oxidative stress+++GO:0050435///amyloid-beta metabolic process+++GO:0050890///cognition+++GO:0060070///canonical Wnt signaling pathway+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1905166///negative regulation of lysosomal protein catabolic process 17311 17311 'Kitl' mRNA 375 407 379 3.68 3.94 3.93 3.35 3.35 3.31 3.85 3.336666667 395 386 378 387 386.3333333 0.936144366 -0.014096136 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04640///Hematopoietic cell lineage+++04916///Melanogenesis+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0042995///cell projection GO:0005125///cytokine activity+++GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001541///ovarian follicle development+++GO:0001755///neural crest cell migration+++GO:0002687///positive regulation of leukocyte migration+++GO:0002763///positive regulation of myeloid leukocyte differentiation+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007281///germ cell development+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0033026///negative regulation of mast cell apoptotic process+++GO:0035162///embryonic hemopoiesis+++GO:0035234///ectopic germ cell programmed cell death+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0070668///positive regulation of mast cell proliferation+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1902035///positive regulation of hematopoietic stem cell proliferation 17312 17312 'Clec10a' mRNA 166.35 167.21 181.66 6.56 6.5 7.6 33.01 33.67 32.27 6.886666667 32.98333333 961.66 957.55 909.89 171.74 943.0333333 2.89E-90 2.446362799 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0002248///connective tissue replacement involved in inflammatory response wound healing+++GO:0044419///interspecies interaction between organisms 17313 17313 'Mgp' mRNA 2322 2336 2374 283.92 284.27 308.12 1915.15 1891.48 1978.43 292.1033333 1928.353333 17875 17162 17799 2344 17612 0 2.896449453 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0048306///calcium-dependent protein binding GO:0001503///ossification+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030500///regulation of bone mineralization+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0051216///cartilage development+++GO:0065003///protein-containing complex assembly 17314 17314 'Mgmt' mRNA 41 52 64 3.31 3.65 5.15 9.72 8.45 12.04 4.036666667 10.07 152 127 171 52.33333333 150 4.30E-08 1.500734224 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0003908///methylated-DNA-[protein]-cysteine S-methyltransferase activity+++GO:0005509///calcium ion binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009636///response to toxic substance+++GO:0014070///response to organic cyclic compound+++GO:0032259///methylation+++GO:0034599///cellular response to oxidative stress+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045471///response to ethanol+++GO:0045739///positive regulation of DNA repair+++GO:0051593///response to folic acid+++GO:0060548///negative regulation of cell death+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0071479///cellular response to ionizing radiation+++GO:2000781///positive regulation of double-strand break repair 17318 17318 'Mid1' mRNA 474 462 349 10.17 9.56 7.49 5.84 5.36 6.69 9.073333333 5.963333333 333 280 341 428.3333333 318 0.004063323 -0.437004401 04120///Ubiquitin mediated proteolysis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding GO:0007026///negative regulation of microtubule depolymerization+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0035372///protein localization to microtubule 17319 17319 'Mif' mRNA 4614 4400 4504 617.09 586.39 639.45 679.97 692.1 692.89 614.31 688.32 5797 5733 5691 4506 5740.333333 3.99E-08 0.336499232 00350///Tyrosine metabolism+++00360///Phenylalanine metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043209///myelin sheath GO:0002020///protease binding+++GO:0004167///dopachrome isomerase activity+++GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0016853///isomerase activity+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0050178///phenylpyruvate tautomerase activity "GO:0001516///prostaglandin biosynthetic process+++GO:0001819///positive regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002035///brain renin-angiotensin system+++GO:0002376///immune system process+++GO:0002675///positive regulation of acute inflammatory response+++GO:0002821///positive regulation of adaptive immune response+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0006954///inflammatory response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007569///cell aging+++GO:0010629///negative regulation of gene expression+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0019752///carboxylic acid metabolic process+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0030336///negative regulation of cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0042327///positive regulation of phosphorylation+++GO:0042756///drinking behavior+++GO:0043066///negative regulation of apoptotic process+++GO:0043268///positive regulation of potassium ion transport+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045087///innate immune response+++GO:0045821///positive regulation of glycolytic process+++GO:0046326///positive regulation of glucose import+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048680///positive regulation of axon regeneration+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050778///positive regulation of immune response+++GO:0050918///positive chemotaxis+++GO:0051726///regulation of cell cycle+++GO:0061078///positive regulation of prostaglandin secretion involved in immune response+++GO:0061081///positive regulation of myeloid leukocyte cytokine production involved in immune response+++GO:0070207///protein homotrimerization+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071157///negative regulation of cell cycle arrest+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0090344///negative regulation of cell aging+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production" 17329 17329 'Cxcl9' mRNA 19 3 10 0.36 0.06 0.2 1.38 1.1 1.41 0.206666667 1.296666667 84 65 83 10.66666667 77.33333333 2.73E-09 2.842867738 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04620///Toll-like receptor signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0045236///CXCR chemokine receptor binding+++GO:0048248///CXCR3 chemokine receptor binding GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0042127///regulation of cell proliferation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051607///defense response to virus+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901741///positive regulation of myoblast fusion 17330 17330 'Minpp1' mRNA 993 1164 1116 21.04 24.28 25.09 22.18 24.77 25.42 23.47 24.12333333 1204 1313 1336 1091 1284.333333 0.034418987 0.223530099 00010///Glycolysis / Gluconeogenesis+++00562///Inositol phosphate metabolism GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0003993///acid phosphatase activity+++GO:0004446///inositol-hexakisphosphate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030351///inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity+++GO:0030352///inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity+++GO:0034417///bisphosphoglycerate 3-phosphatase activity+++GO:0052745///inositol phosphate phosphatase activity+++GO:0052826///inositol hexakisphosphate 2-phosphatase activity" GO:0016311///dephosphorylation 17339 17339 'Mip' mRNA 0 2 1 0 0.05 0.03 0.02 0.02 0.02 0.026666667 0.02 1 1 1 1 1 0.998591786 -0.006932134 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005921///gap junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0046691///intracellular canaliculus "GO:0000268///peroxisome targeting sequence binding+++GO:0004046///aminoacylase activity+++GO:0004096///catalase activity+++GO:0004601///peroxidase activity+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015250///water channel activity+++GO:0015267///channel activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050661///NADP binding" GO:0000302///response to reactive oxygen species+++GO:0001657///ureteric bud development+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0002088///lens development in camera-type eye+++GO:0006641///triglyceride metabolic process+++GO:0006833///water transport+++GO:0006979///response to oxidative stress+++GO:0007154///cell communication+++GO:0007568///aging+++GO:0007601///visual perception+++GO:0008203///cholesterol metabolic process+++GO:0009060///aerobic respiration+++GO:0009314///response to radiation+++GO:0009411///response to UV+++GO:0009636///response to toxic substance+++GO:0009642///response to light intensity+++GO:0009650///UV protection+++GO:0010193///response to ozone+++GO:0010288///response to lead ion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0014854///response to inactivity+++GO:0015722///canalicular bile acid transport+++GO:0020027///hemoglobin metabolic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032355///response to estradiol+++GO:0032868///response to insulin+++GO:0033189///response to vitamin A+++GO:0033197///response to vitamin E+++GO:0033591///response to L-ascorbic acid+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0045785///positive regulation of cell adhesion+++GO:0046686///response to cadmium ion+++GO:0050896///response to stimulus+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051289///protein homotetramerization+++GO:0051781///positive regulation of cell division+++GO:0055085///transmembrane transport+++GO:0055093///response to hyperoxia+++GO:0070542///response to fatty acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0080184///response to phenylpropanoid+++GO:0098869///cellular oxidant detoxification+++GO:1990349///gap junction-mediated intercellular transport 17341 17341 'Bhlha15' mRNA 35 11 25 0.54 0.17 0.41 0.85 0.91 0.6 0.373333333 0.786666667 63 66 43 23.66666667 57.33333333 0.007573224 1.259830213 04950///Maturity onset diabetes of the young GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0007030///Golgi organization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0010832///negative regulation of myotube differentiation+++GO:0019722///calcium-mediated signaling+++GO:0030182///neuron differentiation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0042149///cellular response to glucose starvation+++GO:0042593///glucose homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048312///intracellular distribution of mitochondria+++GO:0048469///cell maturation" 17342 17342 'Mitf' mRNA 541.62 526.01 511.48 5.6 5.23 5.55 6.94 6.14 6.51 5.46 6.53 790.53 676.62 739.23 526.37 735.46 1.48E-05 0.47000553 04137///Mitophagy - animal+++04380///Osteoclast differentiation+++04916///Melanogenesis+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05218///Melanoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030316///osteoclast differentiation+++GO:0030318///melanocyte differentiation+++GO:0030336///negative regulation of cell migration+++GO:0042127///regulation of cell proliferation+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0045165///cell fate commitment+++GO:0045670///regulation of osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046849///bone remodeling+++GO:0065003///protein-containing complex assembly+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:2001141///regulation of RNA biosynthetic process" 17344 17344 'Pias2' mRNA 1127 1142 654 19.77 20.53 10.73 7.99 9.78 10.3 17.01 9.356666667 591 730 730 974.3333333 683.6666667 0.001732657 -0.50885747 04120///Ubiquitin mediated proteolysis+++04630///JAK-STAT signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0016607///nuclear speck GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035259///glucocorticoid receptor binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0061665///SUMO ligase activity "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016925///protein sumoylation+++GO:0030521///androgen receptor signaling pathway+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045667///regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0060766///negative regulation of androgen receptor signaling pathway" 17345 17345 'Mki67' mRNA 21 20 23 0.11 0.11 0.13 3.63 3.26 3.79 0.116666667 3.56 783 677 797 21.33333333 752.3333333 2.55E-120 5.127693039 "GO:0000775///chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division+++GO:0008283///cell proliferation+++GO:0051321///meiotic cell cycle+++GO:0051983///regulation of chromosome segregation+++GO:0072574///hepatocyte proliferation+++GO:1902275///regulation of chromatin organization+++GO:1990705///cholangiocyte proliferation 17346 17346 'Mknk1' mRNA 657 680 672 14.3 14.42 15.36 23.88 24.36 22.88 14.69333333 23.70666667 1269 1257 1169 669.6666667 1231.666667 2.55E-21 0.866655374 04010///MAPK signaling pathway+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0006468///protein phosphorylation+++GO:0009651///response to salt stress+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 17347 17347 'Mknk2' mRNA 848 840 918 13.88 13.54 16.03 22.19 20.62 21.08 14.48333333 21.29666667 1553 1411 1432 868.6666667 1465.333333 1.09E-15 0.739209171 04010///MAPK signaling pathway+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030097///hemopoiesis+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation+++GO:0071243///cellular response to arsenic-containing substance+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 17349 17349 'Mlf1' mRNA 1266 1273 1249 70.72 70.25 73.99 10.13 11.24 12.28 71.65333333 11.21666667 208 225 244 1262.666667 225.6666667 5.56E-116 -2.495787749 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base+++GO:0097730///non-motile cilium GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding "GO:0002318///myeloid progenitor cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0051726///regulation of cell cycle" 17350 17350 'Mlh1' mRNA 568 496 549 11.81 10.1 12.32 9.25 9.07 9.1 11.41 9.14 512 495 490 537.6666667 499 0.400993295 -0.121409236 01524///Platinum drug resistance+++03430///Mismatch repair+++03460///Fanconi anemia pathway+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05226///Gastric cancer GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005712///chiasma+++GO:0005715///late recombination nodule+++GO:0032300///mismatch repair complex+++GO:0032389///MutLalpha complex GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0030983///mismatched DNA binding+++GO:0032137///guanine/thymine mispair binding+++GO:0032407///MutSalpha complex binding GO:0000237///leptotene+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000712///resolution of meiotic recombination intermediates+++GO:0002204///somatic recombination of immunoglobulin genes involved in immune response+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007060///male meiosis chromosome segregation+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009617///response to bacterium+++GO:0016321///female meiosis chromosome segregation+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0043060///meiotic metaphase I plate congression+++GO:0045132///meiotic chromosome segregation+++GO:0045141///meiotic telomere clustering+++GO:0045143///homologous chromosome segregation+++GO:0045190///isotype switching+++GO:0045950///negative regulation of mitotic recombination+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0048477///oogenesis+++GO:0051257///meiotic spindle midzone assembly+++GO:0051321///meiotic cell cycle 17354 17354 'Mllt10' mRNA 647.72 654.27 514.18 6.37 6.13 5.44 4.21 3.76 4.43 5.98 4.133333333 492.36 425.76 505.44 605.39 474.52 0.004594488 -0.360240134 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0045944///positive regulation of transcription by RNA polymerase II 17355 17355 'Aff1' mRNA 1865 1722 1592 11.75 10.65 10.64 12.28 10.81 12.7 11.01333333 11.93 2246 1935 2247 1726.333333 2142.666667 2.48E-04 0.300617055 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0008023///transcription elongation factor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032783///ELL-EAF complex GO:0003700///DNA-binding transcription factor activity "GO:0006351///transcription, DNA-templated+++GO:0010468///regulation of gene expression+++GO:0045893///positive regulation of transcription, DNA-templated" 17356 17356 'Afdn' mRNA 1532 1469 1290 10.67 10.1 9.56 5.65 4.62 5.27 10.11 5.18 932 739 837 1430.333333 836 5.10E-17 -0.785782569 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04520///Adherens junction+++04530///Tight junction+++04670///Leukocyte transendothelial migration GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0036477///somatodendritic compartment+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0045177///apical part of cell+++GO:0046930///pore complex+++GO:0060076///excitatory synapse+++GO:0070160///tight junction GO:0005515///protein binding+++GO:0030274///LIM domain binding+++GO:0031267///small GTPase binding+++GO:0050839///cell adhesion molecule binding+++GO:0051015///actin filament binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0021537///telencephalon development+++GO:0021987///cerebral cortex development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0032880///regulation of protein localization+++GO:0034334///adherens junction maintenance+++GO:0043547///positive regulation of GTPase activity+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0046931///pore complex assembly+++GO:0048854///brain morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0060019///radial glial cell differentiation+++GO:0060563///neuroepithelial cell differentiation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061885///positive regulation of mini excitatory postsynaptic potential+++GO:0061951///establishment of protein localization to plasma membrane+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0070830///bicellular tight junction assembly+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0140059///dendrite arborization+++GO:1902414///protein localization to cell junction+++GO:1903861///positive regulation of dendrite extension+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin 17357 17357 'Marcksl1' mRNA 3145 3250 991 114.98 117.16 38.44 62.69 153.67 126.02 90.19333333 114.1266667 1970 4713 3832 2462 3505 0.490135805 0.5300539 04666///Fc gamma R-mediated phagocytosis+++05140///Leishmaniasis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0099026///anchored component of presynaptic membrane+++GO:0099523///presynaptic cytosol GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0051015///actin filament binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels GO:0007015///actin filament organization+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration 17364 17364 'Trpm1' mRNA 170 192 159 3.12 3.46 3.07 1.87 1.03 0.98 3.216666667 1.293333333 115 65 60 173.6666667 80 1.57E-05 -1.132797456 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0035841///new growing cell tip+++GO:0042995///cell projection GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007601///visual perception+++GO:0016048///detection of temperature stimulus+++GO:0034220///ion transmembrane transport+++GO:0034613///cellular protein localization+++GO:0046548///retinal rod cell development+++GO:0050896///response to stimulus+++GO:0050951///sensory perception of temperature stimulus+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0060402///calcium ion transport into cytosol+++GO:0070588///calcium ion transmembrane transport+++GO:0071482///cellular response to light stimulus+++GO:0098655///cation transmembrane transport 17380 17380 'Mme' mRNA 1185 1256 1200 10.56 11.06 11.47 7.78 7.12 6.97 11.03 7.29 1002 893 870 1213.666667 921.6666667 6.26E-06 -0.410038534 04614///Renin-angiotensin system+++04640///Hematopoietic cell lineage+++04974///Protein digestion and absorption+++05010///Alzheimer disease GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0044306///neuron projection terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098793///presynapse GO:0001786///phosphatidylserine binding+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008238///exopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070012///oligopeptidase activity+++GO:1901612///cardiolipin binding GO:0001822///kidney development+++GO:0001890///placenta development+++GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0007568///aging+++GO:0007611///learning or memory+++GO:0016485///protein processing+++GO:0019233///sensory perception of pain+++GO:0030324///lung development+++GO:0046449///creatinine metabolic process+++GO:0050435///amyloid-beta metabolic process+++GO:0050769///positive regulation of neurogenesis+++GO:0061837///neuropeptide processing+++GO:0071345///cellular response to cytokine stimulus+++GO:0071492///cellular response to UV-A+++GO:0071493///cellular response to UV-B+++GO:0090399///replicative senescence+++GO:0097242///amyloid-beta clearance+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1900273///positive regulation of long-term synaptic potentiation 17381 17381 'Mmp12' mRNA 5 9 10 0.16 0.26 0.34 25.97 23.47 24.18 0.253333333 24.54 976 877 897 8 916.6666667 8.36E-103 6.828133229 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0001046///core promoter sequence-specific DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006606///protein import into nucleus+++GO:0010628///positive regulation of gene expression+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0032727///positive regulation of interferon-alpha production+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0050691///regulation of defense response to virus by host+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0060309///elastin catabolic process+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060435///bronchiole development+++GO:0098586///cellular response to virus+++GO:1901163///regulation of trophoblast cell migration+++GO:1904905///negative regulation of endothelial cell-matrix adhesion via fibronectin" 17385 17385 'Mmp11' mRNA 721 750 585 18.26 18.84 15.85 27.18 26.21 26.36 17.65 26.58333333 1242 1162 1159 685.3333333 1187.666667 9.59E-17 0.785107778 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007275///multicellular organism development+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030574///collagen catabolic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0071711///basement membrane organization 17386 17386 'Mmp13' mRNA 7 9 8 0.14 0.18 0.18 2.41 2.73 2.98 0.166666667 2.706666667 134 148 160 8 147.3333333 1.13E-26 4.1932917 "04657///IL-17 signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0031012///extracellular matrix+++GO:0046581///intercellular canaliculus GO:0001968///fibronectin binding+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0001958///endochondral ossification+++GO:0003417///growth plate cartilage development+++GO:0006508///proteolysis+++GO:0007507///heart development+++GO:0009725///response to hormone+++GO:0022617///extracellular matrix disassembly+++GO:0030198///extracellular matrix organization+++GO:0030282///bone mineralization+++GO:0030574///collagen catabolic process+++GO:0043171///peptide catabolic process+++GO:0044267///cellular protein metabolic process+++GO:0051216///cartilage development+++GO:0060349///bone morphogenesis+++GO:1904244///positive regulation of pancreatic trypsinogen secretion 17387 17387 'Mmp14' mRNA 2079.03 2133.39 997 29.61 29.88 15.06 22.63 32.04 29.04 24.85 27.90333333 1829.16 2530 2273.53 1736.473333 2210.896667 0.398466289 0.356648669 "04668///TNF signaling pathway+++04912///GnRH signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0044354///macropinosome+++GO:0045111///intermediate filament cytoskeleton GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005178///integrin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001666///response to hypoxia+++GO:0001935///endothelial cell proliferation+++GO:0001958///endochondral ossification+++GO:0006508///proteolysis+++GO:0006979///response to oxidative stress+++GO:0008584///male gonad development+++GO:0009612///response to mechanical stimulus+++GO:0009725///response to hormone+++GO:0010831///positive regulation of myotube differentiation+++GO:0010954///positive regulation of protein processing+++GO:0014070///response to organic cyclic compound+++GO:0016477///cell migration+++GO:0030198///extracellular matrix organization+++GO:0030307///positive regulation of cell growth+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0031638///zymogen activation+++GO:0035987///endodermal cell differentiation+++GO:0035988///chondrocyte proliferation+++GO:0043615///astrocyte cell migration+++GO:0043627///response to estrogen+++GO:0045579///positive regulation of B cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048771///tissue remodeling+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0060322///head development+++GO:0060348///bone development+++GO:0097094///craniofacial suture morphogenesis+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1905523///positive regulation of macrophage migration+++GO:1990834///response to odorant 17388 17388 'Mmp15' mRNA 1982 2104 796 24.67 25.76 10.51 8.68 13.08 12.33 20.31333333 11.36333333 803 1182 1104 1627.333333 1029.666667 0.195933894 -0.647734777 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0032355///response to estradiol+++GO:0035987///endodermal cell differentiation 17389 17389 'Mmp16' mRNA 245 240 229 4.04 3.86 3.99 1.24 1.13 1.65 3.963333333 1.34 85 78 110 238 91 8.00E-12 -1.398241425 "04928///Parathyroid hormone synthesis, secretion and action+++05206///MicroRNAs in cancer" GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001958///endochondral ossification+++GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0035988///chondrocyte proliferation+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0060348///bone development+++GO:0097094///craniofacial suture morphogenesis 17390 17390 'Mmp2' mRNA 2016 2219 2089 35.97 38.96 39.54 51.22 53.66 49.39 38.15666667 51.42333333 3304 3380 3084 2108 3256 8.98E-18 0.615463958 01522///Endocrine resistance+++04670///Leukocyte transendothelial migration+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05219///Bladder cancer+++05415///Diabetic cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0031012///extracellular matrix GO:0001968///fibronectin binding+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001666///response to hypoxia+++GO:0001955///blood vessel maturation+++GO:0001957///intramembranous ossification+++GO:0006508///proteolysis+++GO:0006979///response to oxidative stress+++GO:0007162///negative regulation of cell adhesion+++GO:0007507///heart development+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0014012///peripheral nervous system axon regeneration+++GO:0016477///cell migration+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0034614///cellular response to reactive oxygen species+++GO:0035987///endodermal cell differentiation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043627///response to estrogen+++GO:0045089///positive regulation of innate immune response+++GO:0045906///negative regulation of vasoconstriction+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048705///skeletal system morphogenesis+++GO:0048771///tissue remodeling+++GO:0060325///face morphogenesis+++GO:0060346///bone trabecula formation+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071492///cellular response to UV-A+++GO:1904645///response to amyloid-beta+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation 17391 17391 'Mmp24' mRNA 139.47 127.97 104.42 1.74 1.57 1.38 0.27 0.31 0.33 1.563333333 0.303333333 24.9 27.85 29.16 123.9533333 27.30333333 3.33E-13 -2.216147686 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0032588///trans-Golgi network membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0010001///glial cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0097150///neuronal stem cell population maintenance+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 17392 17392 'Mmp3' mRNA 1 0 0 0.03 0 0 2.34 1.97 2.42 0.01 2.243333333 84 69 84 0.333333333 79 1.02E-09 7.771613574 04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05171///Coronavirus disease - COVID-19+++05202///Transcriptional misregulation in cancer+++05215///Prostate cancer+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0044297///cell body GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0030163///protein catabolic process+++GO:0030198///extracellular matrix organization+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0031334///positive regulation of protein complex assembly+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0071492///cellular response to UV-A+++GO:1903209///positive regulation of oxidative stress-induced cell death 17393 17393 'Mmp7' mRNA 9 8 8 0.54 0.47 0.5 9.31 7.91 9.2 0.503333333 8.806666667 181 150 173 8.333333333 168 1.61E-30 4.321216989 04310///Wnt signaling pathway+++05166///Human T-cell leukemia virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002779///antibacterial peptide secretion+++GO:0002780///antibacterial peptide biosynthetic process+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007568///aging+++GO:0009410///response to xenobiotic stimulus+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0031667///response to nutrient levels+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042742///defense response to bacterium+++GO:0044849///estrous cycle+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060135///maternal process involved in female pregnancy+++GO:0071260///cellular response to mechanical stimulus 17394 17394 'Mmp8' mRNA 19 23 13 0.43 0.52 0.31 4.27 4.74 4.19 0.42 4.4 216 234 205 18.33333333 218.3333333 1.90E-35 3.567570001 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035987///endodermal cell differentiation+++GO:0043388///positive regulation of DNA binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0046330///positive regulation of JNK cascade+++GO:0150078///positive regulation of neuroinflammatory response+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903980///positive regulation of microglial cell activation 17395 17395 'Mmp9' mRNA 54 72 52 0.93 1.22 0.95 2.2 2.56 2.74 1.033333333 2.5 147 167 177 59.33333333 163.6666667 3.58E-09 1.457123568 01522///Endocrine resistance+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04915///Estrogen signaling pathway+++04926///Relaxin signaling pathway+++05161///Hepatitis B+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++05219///Bladder cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002687///positive regulation of leukocyte migration+++GO:0006508///proteolysis+++GO:0006979///response to oxidative stress+++GO:0007507///heart development+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0009410///response to xenobiotic stimulus+++GO:0019087///transformation of host cell by virus+++GO:0030198///extracellular matrix organization+++GO:0030335///positive regulation of cell migration+++GO:0030574///collagen catabolic process+++GO:0031915///positive regulation of synaptic plasticity+++GO:0034614///cellular response to reactive oxygen species+++GO:0035987///endodermal cell differentiation+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048771///tissue remodeling+++GO:0050900///leukocyte migration+++GO:0051549///positive regulation of keratinocyte migration+++GO:0071276///cellular response to cadmium ion+++GO:0071460///cellular response to cell-matrix adhesion+++GO:0071492///cellular response to UV-A+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1900122///positive regulation of receptor binding+++GO:1904645///response to amyloid-beta+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000697///negative regulation of epithelial cell differentiation involved in kidney development+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:2001258///negative regulation of cation channel activity+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 17420 17420 'Mnat1' mRNA 513 565 595 18.52 20.23 22.29 16.44 18.88 17.63 20.34666667 17.65 526 566 566 557.6666667 552.6666667 0.867905781 -0.026631838 03022///Basal transcription factors+++03420///Nucleotide excision repair GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005675///transcription factor TFIIH holo complex+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0070516///CAK-ERCC2 complex+++GO:0070985///transcription factor TFIIK complex GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007512///adult heart development+++GO:0021591///ventricular system development+++GO:0043066///negative regulation of apoptotic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051592///response to calcium ion+++GO:1905775///negative regulation of DNA helicase activity" 17423 17423 'Ndst2' mRNA 229 213 216 3.17 2.9 3.17 4.14 3.66 4.58 3.08 4.126666667 344 297 369 219.3333333 336.6666667 1.56E-04 0.605448209 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0008146///sulfotransferase activity+++GO:0015016///[heparan sulfate]-glucosamine N-sulfotransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity "GO:0002002///regulation of angiotensin levels in blood+++GO:0002448///mast cell mediated immunity+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0008152///metabolic process+++GO:0009987///cellular process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0030210///heparin biosynthetic process" 17425 17425 'Foxk1' mRNA 229 261 161 1.62 1.82 1.26 1.36 1 1.29 1.566666667 1.216666667 212 149 193 217 184.6666667 0.320422351 -0.238598318 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0071889///14-3-3 protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001678///cellular glucose homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0008150///biological_process+++GO:0010507///negative regulation of autophagy+++GO:0010906///regulation of glucose metabolic process+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0042594///response to starvation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061621///canonical glycolysis" 17427 17427 'Mns1' mRNA 685.56 733.22 656.02 18.73 20.39 18.69 3.55 3.83 2.36 19.27 3.246666667 147.39 155.44 100.09 691.6 134.3066667 5.60E-55 -2.377890003 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0042802///identical protein binding GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0044782///cilium organization+++GO:0045724///positive regulation of cilium assembly+++GO:0051321///meiotic cell cycle+++GO:0070986///left/right axis specification 17428 17428 'Mnt' mRNA 474 489 284 5.53 5.61 3.51 4.19 4.16 4.83 4.883333333 4.393333333 414 400 462 415.6666667 425.3333333 0.882667669 0.032138542 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007569///cell aging+++GO:0051726///regulation of cell cycle+++GO:2001234///negative regulation of apoptotic signaling pathway" 17433 17433 'Mobp' mRNA 3 8 11 0.09 0.13 0.25 0.3 0.39 0.44 0.156666667 0.376666667 21 22 25 7.333333333 22.66666667 0.024987331 1.606042886 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030864///cortical actin cytoskeleton+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0017022///myosin binding+++GO:0019911///structural constituent of myelin sheath GO:0007399///nervous system development+++GO:0032289///central nervous system myelin formation 17434 17434 'Mocs2' mRNA 1092 1101 990 41.02 40.94 39.71 46.04 44.18 46.04 40.55666667 45.42 1409 1313 1356 1061 1359.333333 1.79E-05 0.346779954 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors+++04122///Sulfur relay system GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0019008///molybdopterin synthase complex GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0030366///molybdopterin synthase activity+++GO:0042802///identical protein binding GO:0006777///Mo-molybdopterin cofactor biosynthetic process 17436 17436 'Me1' mRNA 3455 3487 2984 60.42 60.05 55.61 26.2 24.85 27.22 58.69333333 26.09 1727 1589 1739 3308.666667 1685 1.09E-48 -0.982973973 00620///Pyruvate metabolism+++01200///Carbon metabolism+++03320///PPAR signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004470///malic enzyme activity+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0005515///protein binding+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0016491///oxidoreductase activity+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050661///NADP binding+++GO:0051287///NAD binding GO:0006090///pyruvate metabolic process+++GO:0006108///malate metabolic process+++GO:0009725///response to hormone+++GO:1902031///regulation of NADP metabolic process 17444 17444 'Grap2' mRNA 12 9 6 0.12 0.09 0.06 0.16 0.04 0.15 0.09 0.116666667 19 5 17 9 13.66666667 0.538593357 0.591870566 04660///T cell receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding 17448 17448 'Mdh2' mRNA 6843 7056 6929 323.75 329.55 347.81 335.64 358.64 349.32 333.7033333 347.8666667 8144 8488 8197 6942.666667 8276.333333 7.11E-05 0.241479663 00020///Citrate cycle (TCA cycle)+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0043209///myelin sheath "GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0016615///malate dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0030060///L-malate dehydrogenase activity+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0046554///malate dehydrogenase (NADP+) activity" GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006107///oxaloacetate metabolic process+++GO:0006108///malate metabolic process+++GO:0006734///NADH metabolic process+++GO:0009060///aerobic respiration+++GO:0019752///carboxylic acid metabolic process 17449 17449 'Mdh1' mRNA 11319 11949 11333 329.91 343.13 350.41 254.6 261.61 259.96 341.15 258.7233333 10042 10073 9924 11533.66667 10013 6.92E-05 -0.215716592 00020///Citrate cycle (TCA cycle)+++00270///Cysteine and methionine metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++04964///Proximal tubule bicarbonate reclamation GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0043209///myelin sheath "GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0016615///malate dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0030060///L-malate dehydrogenase activity+++GO:0051287///NAD binding" GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006107///oxaloacetate metabolic process+++GO:0006108///malate metabolic process+++GO:0006734///NADH metabolic process+++GO:0019674///NAD metabolic process+++GO:0019752///carboxylic acid metabolic process 17450 17450 'Morc1' mRNA 3 0 0 0.05 0 0 0.06 0.03 0 0.016666667 0.03 4 2 0 1 2 0.749855753 0.997851254 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0001662///behavioral fear response+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0040029///regulation of gene expression, epigenetic+++GO:0043046///DNA methylation involved in gamete generation+++GO:0044026///DNA hypermethylation+++GO:2000143///negative regulation of DNA-templated transcription, initiation" 17454 17454 'Mov10' mRNA 896 1030 903 13.43 15.15 14.4 20.15 19.85 21.35 14.32666667 20.45 1548 1463 1580 943 1530.333333 4.50E-16 0.687651408 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043186///P granule GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0032574///5'-3' RNA helicase activity "GO:0010526///negative regulation of transposition, RNA-mediated+++GO:0031047///gene silencing by RNA+++GO:0035194///posttranscriptional gene silencing by RNA+++GO:0035195///gene silencing by miRNA+++GO:0035279///mRNA cleavage involved in gene silencing by miRNA+++GO:0051607///defense response to virus+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0150011///regulation of neuron projection arborization" 17463 17463 'Psmd7' mRNA 2295 2403 2295 83.96 86.69 89.08 113.2 112.54 110.45 86.57666667 112.0633333 3555 3449 3356 2331 3453.333333 1.61E-18 0.554964583 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection GO:0000502///proteasome complex+++GO:0005654///nucleoplasm+++GO:0005838///proteasome regulatory particle GO:0008237///metallopeptidase activity+++GO:0042803///protein homodimerization activity+++GO:0070122///isopeptidase activity GO:0006508///proteolysis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 17470 17470 'Cd200' mRNA 862 934 988 20.93 22.26 25.37 27.75 24.96 24.66 22.85333333 25.79 1312 1157 1132 928 1200.333333 6.51E-04 0.355516272 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body GO:0005515///protein binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion GO:0008285///negative regulation of cell proliferation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0034113///heterotypic cell-cell adhesion+++GO:0043031///negative regulation of macrophage activation+++GO:0050776///regulation of immune response+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0098609///cell-cell adhesion+++GO:0150072///positive regulation of arginase activity+++GO:0150074///positive regulation of protein-glutamine gamma-glutamyltransferase activity+++GO:0150077///regulation of neuroinflammatory response+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1904465///negative regulation of matrix metallopeptidase secretion+++GO:1905522///negative regulation of macrophage migration+++GO:2000405///negative regulation of T cell migration 17472 17472 'Gbp4' mRNA 338.47 321.41 306.42 4.04 3.76 3.89 6.8 7.23 6.87 3.896666667 6.966666667 656.26 677.55 637.4 322.1 657.07 2.43E-18 1.018967411 GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032687///negative regulation of interferon-alpha production+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042832///defense response to protozoan+++GO:0050688///regulation of defense response to virus+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071346///cellular response to interferon-gamma 17474 17474 'Clec4d' mRNA 41 25 23 1.85 1.11 1.1 31.29 29.06 28.45 1.353333333 29.6 797 722 701 29.66666667 740 3.63E-119 4.630247253 04625///C-type lectin receptor signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0034987///immunoglobulin receptor binding+++GO:0038187///pattern recognition receptor activity+++GO:0046872///metal ion binding GO:0002250///adaptive immune response+++GO:0002292///T cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0030887///positive regulation of myeloid dendritic cell activation+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0042742///defense response to bacterium+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044419///interspecies interaction between organisms+++GO:0045087///innate immune response+++GO:0061760///antifungal innate immune response 17475 17475 'Mpdz' mRNA 2064 1958 1730 15.26 14.66 14.12 7.17 6.78 7.4 14.68 7.116666667 1098 1034 1087 1917.333333 1073 6.16E-28 -0.847066848 04391///Hippo signaling pathway - fly+++04530///Tight junction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0035003///subapical complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043220///Schmidt-Lanterman incisure+++GO:0045177///apical part of cell+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding GO:0006886///intracellular protein transport+++GO:0007155///cell adhesion+++GO:0016358///dendrite development+++GO:0031023///microtubule organizing center organization+++GO:0042552///myelination+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0120192///tight junction assembly 17476 17476 'Mpeg1' mRNA 245 294 299 3.12 3.69 4.04 34.98 31.22 33.14 3.616666667 33.11333333 3167 2769 2911 279.3333333 2949 1.37E-275 3.385912824 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0002376///immune system process+++GO:0035915///pore formation in membrane of other organism+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 17480 17480 'Mpl' mRNA 2 9 8 0.05 0.23 0.22 0.27 0.28 0.05 0.166666667 0.2 12 12 2 6.333333333 8.666666667 0.749341091 0.432829945 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0004896///cytokine receptor activity+++GO:0038164///thrombopoietin receptor activity GO:0001780///neutrophil homeostasis+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030220///platelet formation+++GO:0032642///regulation of chemokine production+++GO:0035702///monocyte homeostasis+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0048872///homeostasis of number of cells+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0060216///definitive hemopoiesis+++GO:0070527///platelet aggregation+++GO:0071456///cellular response to hypoxia+++GO:0072091///regulation of stem cell proliferation+++GO:1905221///positive regulation of platelet formation+++GO:1990959///eosinophil homeostasis+++GO:1990960///basophil homeostasis+++GO:2000035///regulation of stem cell division 17523 17523 'Mpo' mRNA 12 11 17 0.26 0.24 0.39 0.11 0.21 0.37 0.296666667 0.23 6 11 19 13.33333333 12 0.863090843 -0.168250808 00983///Drug metabolism - other enzymes+++04145///Phagosome+++04613///Neutrophil extracellular trap formation+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0030141///secretory granule+++GO:0042582///azurophil granule+++GO:0043231///intracellular membrane-bounded organelle GO:0004601///peroxidase activity+++GO:0008201///heparin binding+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0001878///response to yeast+++GO:0002149///hypochlorous acid biosynthetic process+++GO:0002679///respiratory burst involved in defense response+++GO:0006952///defense response+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0009612///response to mechanical stimulus+++GO:0019430///removal of superoxide radicals+++GO:0032094///response to food+++GO:0032496///response to lipopolysaccharide+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0042742///defense response to bacterium+++GO:0042744///hydrogen peroxide catabolic process+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0098869///cellular oxidant detoxification+++GO:1990268///response to gold nanoparticle 17524 17524 'Mpp1' mRNA 679 717 752 14.97 15.56 17.59 53.36 55.21 58.28 16.04 55.61666667 2784 2813 2944 716 2847 1.22E-125 1.978130048 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030863///cortical cytoskeleton+++GO:0032420///stereocilium+++GO:0034451///centriolar satellite+++GO:0042995///cell projection GO:0005515///protein binding GO:0090022///regulation of neutrophil chemotaxis 17527 17527 'Mpv17' mRNA 2253.67 2325.04 2361.2 76.15 77.53 84.65 61.88 66.14 63.15 79.44333333 63.72333333 2105.3 2195.92 2077.31 2313.303333 2126.176667 0.108325683 -0.13467756 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015267///channel activity GO:0000002///mitochondrial genome maintenance+++GO:0007605///sensory perception of sound+++GO:0032836///glomerular basement membrane development+++GO:0034614///cellular response to reactive oxygen species+++GO:0042592///homeostatic process+++GO:0048839///inner ear development+++GO:0072593///reactive oxygen species metabolic process+++GO:1901858///regulation of mitochondrial DNA metabolic process+++GO:2000377///regulation of reactive oxygen species metabolic process 17528 17528 'Mpz' mRNA 26562 25375 19535 801.5 754.47 625.33 635.9 571.3 618.97 727.1 608.7233333 24225 21245 22821 23824 22763.66667 0.426535524 -0.072521104 04514///Cell adhesion molecules GO:0005764///lysosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043209///myelin sheath GO:0005515///protein binding GO:0042552///myelination+++GO:0043066///negative regulation of apoptotic process+++GO:0045217///cell-cell junction maintenance+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0098743///cell aggregation 17532 17532 'Mras' mRNA 769 770 602 10.26 10.11 8.53 7.04 7.45 7.49 9.633333333 7.326666667 607 628 628 713.6666667 621 0.085513397 -0.207425264 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04218///Cellular senescence+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05205///Proteoglycans in cancer GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0030742///GTP-dependent protein binding GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:1990830///cellular response to leukemia inhibitory factor 17533 17533 'Mrc1' mRNA 642 651 595 6.43 6.41 6.32 43.2 42.1 43.27 6.386666667 42.85666667 4963 4726 4815 629.3333333 4834.666667 0 2.93062535 04145///Phagosome+++05152///Tuberculosis GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0038024///cargo receptor activity GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0071353///cellular response to interleukin-4 17534 17534 'Mrc2' mRNA 1595 1746 1175 14.59 15.71 11.41 15.02 22.54 19.07 13.90333333 18.87666667 1890 2772 2324 1505.333333 2328.666667 0.007175849 0.629781281 04145///Phagosome+++05152///Tuberculosis GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005518///collagen binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity GO:0006897///endocytosis+++GO:0030574///collagen catabolic process 17535 17535 'Mre11a' mRNA 455.91 420.75 440.56 3.95 3.53 4 3.2 4.06 3.77 3.826666667 3.676666667 421.29 452.43 426.5 439.0733333 433.4066667 0.863090843 -0.029764657 03440///Homologous recombination+++03450///Non-homologous end-joining+++04218///Cellular senescence "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0030870///Mre11 complex+++GO:0035861///site of double-strand break+++GO:0048471///perinuclear region of cytoplasm" GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007062///sister chromatid cohesion+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007129///synapsis+++GO:0008283///cell proliferation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0031860///telomeric 3' overhang formation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0033674///positive regulation of kinase activity+++GO:0042138///meiotic DNA double-strand break formation+++GO:0043066///negative regulation of apoptotic process+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051276///chromosome organization+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0097552///mitochondrial double-strand break repair via homologous recombination+++GO:0110025///DNA strand resection involved in replication fork processing 17536 17536 'Meis2' mRNA 2140 2308 2044 34.49 37.48 36.44 14.9 12.01 13.94 36.13666667 13.61666667 1048 804 919 2164 923.6666667 2.34E-45 -1.240705614 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0009612///response to mechanical stimulus+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0031016///pancreas development+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070848///response to growth factor+++GO:0110024///positive regulation of cardiac muscle myoblast proliferation" 17537 17537 'Meis3' mRNA 729 725 692 22.71 22.38 23.54 14.23 14.67 13.78 22.87666667 14.22666667 518 523 490 715.3333333 510.3333333 2.97E-06 -0.49850052 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0009887///animal organ morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051897///positive regulation of protein kinase B signaling+++GO:2001234///negative regulation of apoptotic signaling pathway" 17540 17540 'Mrvi1' mRNA 50 40 52 0.47 0.35 0.49 0.57 0.84 0.53 0.436666667 0.646666667 69 103 67 47.33333333 79.66666667 0.037187494 0.738595546 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0019934///cGMP-mediated signaling+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0060087///relaxation of vascular smooth muscle 17681 17681 'Msc' mRNA 4 5 5 0.14 0.23 0.17 0.73 0.75 1.28 0.18 0.92 23 25 42 4.666666667 30 1.03E-04 2.673909836 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0014707///branchiomeric skeletal muscle development+++GO:0032502///developmental process+++GO:0060021///roof of mouth development+++GO:0060539///diaphragm development+++GO:1990830///cellular response to leukemia inhibitory factor 17684 17684 'Cited2' mRNA 615 591 351 17.62 16.71 10.67 7.63 7.98 8.81 15 8.14 310 312 344 519 322 7.36E-05 -0.689138378 04137///Mitophagy - animal GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0035035///histone acetyltransferase binding+++GO:0046332///SMAD binding+++GO:0050693///LBD domain binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001829///trophectodermal cell differentiation+++GO:0001841///neural tube formation+++GO:0001843///neural tube closure+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0001944///vasculature development+++GO:0001947///heart looping+++GO:0002009///morphogenesis of an epithelium+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002521///leukocyte differentiation+++GO:0003151///outflow tract morphogenesis+++GO:0003156///regulation of animal organ formation+++GO:0003197///endocardial cushion development+++GO:0003281///ventricular septum development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007417///central nervous system development+++GO:0007422///peripheral nervous system development+++GO:0007507///heart development+++GO:0007530///sex determination+++GO:0007569///cell aging+++GO:0008283///cell proliferation+++GO:0008584///male gonad development+++GO:0009612///response to mechanical stimulus+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0021602///cranial nerve morphogenesis+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030325///adrenal gland development+++GO:0030336///negative regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030851///granulocyte differentiation+++GO:0034405///response to fluid shear stress+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0035802///adrenal cortex formation+++GO:0035914///skeletal muscle cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043627///response to estrogen+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046697///decidualization+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048821///erythrocyte development+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060136///embryonic process involved in female pregnancy+++GO:0060349///bone morphogenesis+++GO:0060411///cardiac septum morphogenesis+++GO:0060412///ventricular septum morphogenesis+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0060972///left/right pattern formation+++GO:0061156///pulmonary artery morphogenesis+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0061371///determination of heart left/right asymmetry+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0070986///left/right axis specification+++GO:0071363///cellular response to growth factor stimulus+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:2000020///positive regulation of male gonad development" 17685 17685 'Msh2' mRNA 897 923 907 15.96 16.16 17.12 9.94 9.28 9.02 16.41333333 9.413333333 643 586 565 909 598 7.27E-10 -0.617272192 01524///Platinum drug resistance+++03430///Mismatch repair+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0032300///mismatch repair complex+++GO:0032301///MutSalpha complex+++GO:0032302///MutSbeta complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000400///four-way junction DNA binding+++GO:0000406///double-strand/single-strand DNA junction binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016887///ATPase activity+++GO:0019237///centromeric DNA binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030983///mismatched DNA binding+++GO:0032137///guanine/thymine mispair binding+++GO:0032139///dinucleotide insertion or deletion binding+++GO:0032142///single guanine insertion binding+++GO:0032143///single thymine insertion binding+++GO:0032181///dinucleotide repeat insertion binding+++GO:0032357///oxidized purine DNA binding+++GO:0032405///MutLalpha complex binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding GO:0001701///in utero embryonic development+++GO:0002204///somatic recombination of immunoglobulin genes involved in immune response+++GO:0006119///oxidative phosphorylation+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006301///postreplication repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007281///germ cell development+++GO:0008340///determination of adult lifespan+++GO:0008584///male gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010165///response to X-ray+++GO:0010224///response to UV-B+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0019724///B cell mediated immunity+++GO:0030183///B cell differentiation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043570///maintenance of DNA repeat elements+++GO:0045190///isotype switching+++GO:0045910///negative regulation of DNA recombination+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0051096///positive regulation of helicase activity+++GO:0051726///regulation of cell cycle+++GO:0071168///protein localization to chromatin 17686 17686 'Msh3' mRNA 444.32 378.47 406.5 6.16 5.16 6 3.17 3.22 3.1 5.773333333 3.163333333 266.3 262.93 254.2 409.7633333 261.1433333 4.47E-06 -0.663823564 01524///Platinum drug resistance+++03430///Mismatch repair+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0005634///nucleus+++GO:0032300///mismatch repair complex+++GO:0032302///MutSbeta complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0019237///centromeric DNA binding+++GO:0019899///enzyme binding+++GO:0030983///mismatched DNA binding+++GO:0032135///DNA insertion or deletion binding+++GO:0032139///dinucleotide insertion or deletion binding+++GO:0032142///single guanine insertion binding+++GO:0032181///dinucleotide repeat insertion binding GO:0000710///meiotic mismatch repair+++GO:0000735///removal of nonhomologous ends+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006312///mitotic recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0043111///replication fork arrest+++GO:0043570///maintenance of DNA repeat elements+++GO:0045910///negative regulation of DNA recombination+++GO:0051096///positive regulation of helicase activity 17687 17687 'Msh5' mRNA 37 51 51 0.75 1.02 1.19 0.55 0.4 1.07 0.986666667 0.673333333 32 20 52 46.33333333 34.66666667 0.399245498 -0.434609017 GO:0000228///nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0030983///mismatched DNA binding GO:0000710///meiotic mismatch repair+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007127///meiosis I+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0007292///female gamete generation+++GO:0051321///meiotic cell cycle 17688 17688 'Msh6' mRNA 588 689 644 7.42 8.55 8.62 9.18 7.74 8.64 8.196666667 8.52 837 690 763 640.3333333 763.3333333 0.046128258 0.239783064 01524///Platinum drug resistance+++03430///Mismatch repair+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0032300///mismatch repair complex+++GO:0032301///MutSalpha complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0019899///enzyme binding+++GO:0030983///mismatched DNA binding+++GO:0032137///guanine/thymine mispair binding+++GO:0032142///single guanine insertion binding+++GO:0032143///single thymine insertion binding+++GO:0032357///oxidized purine DNA binding+++GO:0032405///MutLalpha complex binding+++GO:0035064///methylated histone binding+++GO:0043531///ADP binding GO:0000710///meiotic mismatch repair+++GO:0006281///DNA repair+++GO:0006290///pyrimidine dimer repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009411///response to UV+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0036297///interstrand cross-link repair+++GO:0043570///maintenance of DNA repeat elements+++GO:0045190///isotype switching+++GO:0045910///negative regulation of DNA recombination+++GO:0051096///positive regulation of helicase activity+++GO:0097193///intrinsic apoptotic signaling pathway 17690 17690 'Msi1' mRNA 2493 2039 1839 46.47 37.33 37.56 16.19 15.72 16.99 40.45333333 16.3 988 930 999 2123.666667 972.3333333 1.22E-32 -1.135675435 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0042802///identical protein binding GO:0009725///response to hormone 17691 17691 'Sik1' mRNA 396 419 225 4.72 4.89 2.84 5.23 4.9 6.36 4.15 5.496666667 506 462 598 346.6666667 522 0.00143964 0.590508439 04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008140///cAMP response element binding protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002028///regulation of sodium ion transport+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0010830///regulation of myotube differentiation+++GO:0010868///negative regulation of triglyceride biosynthetic process+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043276///anoikis+++GO:0045595///regulation of cell differentiation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046777///protein autophosphorylation+++GO:0048511///rhythmic process+++GO:0055007///cardiac muscle cell differentiation+++GO:2000210///positive regulation of anoikis 17692 17692 'Msl3' mRNA 722 777 781 10.72 11.07 12.35 11.48 10.85 11.13 11.38 11.15333333 890 814 843 760 849 0.197284964 0.145986692 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0072487///MSL complex GO:0003677///DNA binding+++GO:0035064///methylated histone binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific) "GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016573///histone acetylation+++GO:0016575///histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0043984///histone H4-K16 acetylation" 17698 17698 'Msn' mRNA 1499 1619 1574 21.12 22.44 23.52 110.59 107.38 107.72 22.36 108.5633333 9035 8570 8523 1564 8709.333333 0 2.46454793 04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05162///Measles+++05205///Proteoglycans in cancer GO:0001931///uropod+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030175///filopodium+++GO:0030315///T-tubule+++GO:0030667///secretory granule membrane+++GO:0031143///pseudopodium+++GO:0031527///filopodium membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip+++GO:0071944///cell periphery GO:0003725///double-stranded RNA binding+++GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0050839///cell adhesion molecule binding GO:0001771///immunological synapse formation+++GO:0007159///leukocyte cell-cell adhesion+++GO:0008360///regulation of cell shape+++GO:0008361///regulation of cell size+++GO:0010628///positive regulation of gene expression+++GO:0022612///gland morphogenesis+++GO:0022614///membrane to membrane docking+++GO:0042098///T cell proliferation+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0050900///leukocyte migration+++GO:0061028///establishment of endothelial barrier+++GO:0070489///T cell aggregation+++GO:0071394///cellular response to testosterone stimulus+++GO:0071803///positive regulation of podosome assembly+++GO:0072678///T cell migration+++GO:1902115///regulation of organelle assembly+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:2000401///regulation of lymphocyte migration+++GO:2000643///positive regulation of early endosome to late endosome transport 17700 17700 'Mstn' mRNA 6 10 9 0.12 0.2 0.2 0.12 0.02 0.13 0.173333333 0.09 7 1 7 8.333333333 5 0.536879653 -0.75810477 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0009408///response to heat+++GO:0009629///response to gravity+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0014732///skeletal muscle atrophy+++GO:0014741///negative regulation of muscle hypertrophy+++GO:0014839///myoblast migration involved in skeletal muscle regeneration+++GO:0014850///response to muscle activity+++GO:0022602///ovulation cycle process+++GO:0033574///response to testosterone+++GO:0033673///negative regulation of kinase activity+++GO:0043403///skeletal muscle tissue regeneration+++GO:0043627///response to estrogen+++GO:0045471///response to ethanol+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046716///muscle cell cellular homeostasis+++GO:0048632///negative regulation of skeletal muscle tissue growth+++GO:0051384///response to glucocorticoid+++GO:0051602///response to electrical stimulus+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060395///SMAD protein signal transduction+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation+++GO:1902725///negative regulation of satellite cell differentiation+++GO:2000818///negative regulation of myoblast proliferation" 17701 17701 'Msx1' mRNA 14 11 10 0.41 0.32 0.31 0.36 0.63 0.48 0.346666667 0.49 14 24 18 11.66666667 18.66666667 0.361335506 0.673528496 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0003007///heart morphogenesis+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0008285///negative regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0010463///mesenchymal cell proliferation+++GO:0021983///pituitary gland development+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030308///negative regulation of cell growth+++GO:0030326///embryonic limb morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0034504///protein localization to nucleus+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035880///embryonic nail plate morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042476///odontogenesis+++GO:0042481///regulation of odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048598///embryonic morphogenesis+++GO:0048863///stem cell differentiation+++GO:0050821///protein stabilization+++GO:0051154///negative regulation of striated muscle cell differentiation+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0060349///bone morphogenesis+++GO:0060536///cartilage morphogenesis+++GO:0061180///mammary gland epithelium development+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0071316///cellular response to nicotine+++GO:0090427///activation of meiosis+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2001055///positive regulation of mesenchymal cell apoptotic process" 17702 17702 'Msx2' mRNA 6 10 6 0.16 0.26 0.17 0.2 0.05 0.26 0.196666667 0.17 9 2 11 7.333333333 7.333333333 0.998591786 -0.011069653 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0002063///chondrocyte development+++GO:0002076///osteoblast development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003416///endochondral bone growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0010942///positive regulation of cell death+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030326///embryonic limb morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035880///embryonic nail plate morphogenesis+++GO:0042060///wound healing+++GO:0042476///odontogenesis+++GO:0042640///anagen+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048598///embryonic morphogenesis+++GO:0048863///stem cell differentiation+++GO:0051216///cartilage development+++GO:0051795///positive regulation of timing of catagen+++GO:0060346///bone trabecula formation+++GO:0060349///bone morphogenesis+++GO:0060364///frontal suture morphogenesis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0061180///mammary gland epithelium development+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0070166///enamel mineralization+++GO:0071363///cellular response to growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0090427///activation of meiosis+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2001055///positive regulation of mesenchymal cell apoptotic process" 17703 17703 'Msx3' mRNA 84 111 118 2.06 2.68 3.05 2.93 3.15 3.6 2.596666667 3.226666667 138 144 163 104.3333333 148.3333333 0.051631009 0.492804233 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0035067///negative regulation of histone acetylation+++GO:0048598///embryonic morphogenesis" 17713 17713 'Grpel1' mRNA 1566.98 1467.46 1400.45 25.6 23.59 24.27 27.01 27.26 25.42 24.48666667 26.56333333 1902.59 1875.06 1733.6 1478.296667 1837.083333 1.25E-04 0.302687585 "GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix" GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding GO:0006457///protein folding+++GO:0030150///protein import into mitochondrial matrix+++GO:0050790///regulation of catalytic activity 17714 17714 'Grpel2' mRNA 696 568 670 9.28 7.45 9.48 8.1 7.74 7.73 8.736666667 7.856666667 699 653 646 644.6666667 666 0.860694977 0.031968941 "GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix" GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0042803///protein homodimerization activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0030150///protein import into mitochondrial matrix+++GO:0050790///regulation of catalytic activity 17748 17748 'Mt1' mRNA 1841 1814 2090 271.03 265.9 326.95 485.23 542.1 520.59 287.96 515.9733333 3776 4077 3900 1915 3917.666667 1.20E-31 1.017474724 04212///Longevity regulating pathway - worm+++04978///Mineral absorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol GO:0005507///copper ion binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006875///cellular metal ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0007263///nitric oxide mediated signal transduction+++GO:0010273///detoxification of copper ion+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045926///negative regulation of growth+++GO:0071247///cellular response to chromate+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071294///cellular response to zinc ion 17749 17749 'Polr2k' mRNA 448.7 455.65 507.69 71.75 72.32 85.94 78.5 82.18 74.75 76.67 78.47666667 551.85 557.65 503.82 470.68 537.7733333 0.220599205 0.1773131 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005666///RNA polymerase III complex+++GO:0005736///RNA polymerase I complex" GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 17750 17750 'Mt2' mRNA 400 332 429 57.22 47.38 65.15 124.31 133.68 138.21 56.58333333 132.0666667 990 1034 1060 387 1028 7.93E-30 1.393833175 04212///Longevity regulating pathway - worm+++04978///Mineral absorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0046870///cadmium ion binding+++GO:0046872///metal ion binding GO:0006882///cellular zinc ion homeostasis+++GO:0007263///nitric oxide mediated signal transduction+++GO:0009617///response to bacterium+++GO:0010273///detoxification of copper ion+++GO:0045926///negative regulation of growth+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071294///cellular response to zinc ion 17751 17751 'Mt3' mRNA 1548 1551 1694 233.15 233.2 270.87 160.18 165.53 188.23 245.74 171.3133333 1211 1215 1370 1597.666667 1265.333333 3.65E-04 -0.350855751 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016234///inclusion body+++GO:0030424///axon+++GO:0043197///dendritic spine+++GO:0048471///perinuclear region of cytoplasm+++GO:0097449///astrocyte projection+++GO:0097450///astrocyte end-foot GO:0005507///copper ion binding+++GO:0008270///zinc ion binding+++GO:0030295///protein kinase activator activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046870///cadmium ion binding+++GO:0046872///metal ion binding "GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006112///energy reserve metabolic process+++GO:0006707///cholesterol catabolic process+++GO:0006829///zinc ion transport+++GO:0006875///cellular metal ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0010273///detoxification of copper ion+++GO:0010507///negative regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010940///positive regulation of necrotic cell death+++GO:0010942///positive regulation of cell death+++GO:0014002///astrocyte development+++GO:0016570///histone modification+++GO:0019430///removal of superoxide radicals+++GO:0030308///negative regulation of cell growth+++GO:0030517///negative regulation of axon extension+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032095///regulation of response to food+++GO:0032148///activation of protein kinase B activity+++GO:0033210///leptin-mediated signaling pathway+++GO:0034599///cellular response to oxidative stress+++GO:0036091///positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044242///cellular lipid catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050768///negative regulation of neurogenesis+++GO:0050821///protein stabilization+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0055069///zinc ion homeostasis+++GO:0055073///cadmium ion homeostasis+++GO:0060049///regulation of protein glycosylation+++GO:0060547///negative regulation of necrotic cell death+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071294///cellular response to zinc ion+++GO:0071732///cellular response to nitric oxide+++GO:0097214///positive regulation of lysosomal membrane permeability+++GO:1901215///negative regulation of neuron death+++GO:2000117///negative regulation of cysteine-type endopeptidase activity+++GO:2000296///negative regulation of hydrogen peroxide catabolic process+++GO:2000376///positive regulation of oxygen metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 17752 17752 'Mt4' mRNA 1 0 0 0.26 0 0 0 0 0 0.086666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0046872///metal ion binding GO:0006875///cellular metal ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0010273///detoxification of copper ion+++GO:0046686///response to cadmium ion+++GO:0071276///cellular response to cadmium ion+++GO:0071280///cellular response to copper ion+++GO:0071294///cellular response to zinc ion 17754 17754 'Map1a' mRNA 250 286 237 1.17 1.32 1.18 1.59 1.14 1.42 1.223333333 1.383333333 388 273 334 257.6666667 331.6666667 0.043278279 0.352033486 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0014069///postsynaptic density+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043198///dendritic shaft+++GO:0044307///dendritic branch+++GO:0045202///synapse+++GO:0150001///primary dendrite+++GO:0150034///distal axon+++GO:1901588///dendritic microtubule+++GO:1904115///axon cytoplasm GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0015631///tubulin binding+++GO:0035255///ionotropic glutamate receptor binding GO:0000226///microtubule cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007409///axonogenesis+++GO:0007605///sensory perception of sound+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0016358///dendrite development+++GO:0031114///regulation of microtubule depolymerization+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045494///photoreceptor cell maintenance+++GO:0048167///regulation of synaptic plasticity+++GO:0050882///voluntary musculoskeletal movement+++GO:0070050///neuron cellular homeostasis+++GO:0099641///anterograde axonal protein transport+++GO:0099642///retrograde axonal protein transport+++GO:1902817///negative regulation of protein localization to microtubule+++GO:1903829///positive regulation of cellular protein localization+++GO:1990535///neuron projection maintenance+++GO:2000010///positive regulation of protein localization to cell surface 17755 17755 'Map1b' mRNA 5088 5213 5489 22.39 22.53 25.61 11.13 10.87 10.26 23.51 10.75333333 2917 2785 2605 5263.333333 2769 1.15E-38 -0.941445259 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043196///varicosity+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite+++GO:0097457///hippocampal mossy fiber GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0005543///phospholipid binding+++GO:0008017///microtubule binding+++GO:0044877///protein-containing complex binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007017///microtubule-based process+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007416///synapse assembly+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0009743///response to carbohydrate+++GO:0009987///cellular process+++GO:0010035///response to inorganic substance+++GO:0014012///peripheral nervous system axon regeneration+++GO:0016358///dendrite development+++GO:0017085///response to insecticide+++GO:0021700///developmental maturation+++GO:0031114///regulation of microtubule depolymerization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0032387///negative regulation of intracellular transport+++GO:0033189///response to vitamin A+++GO:0042493///response to drug+++GO:0045666///positive regulation of neuron differentiation+++GO:0045773///positive regulation of axon extension+++GO:0047497///mitochondrion transport along microtubule+++GO:0048666///neuron development+++GO:0048675///axon extension+++GO:0048678///response to axon injury+++GO:0051915///induction of synaptic plasticity by chemical substance+++GO:0061162///establishment of monopolar cell polarity+++GO:0071363///cellular response to growth factor stimulus+++GO:0071375///cellular response to peptide hormone stimulus 17756 17756 'Map2' mRNA 569.28 611.05 532.4 4.75 5.23 4.73 1.96 1.95 1.67 4.903333333 1.86 267.94 248.63 219.2 570.91 245.2566667 2.02E-21 -1.232555025 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032587///ruffle membrane+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0034399///nuclear periphery+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043198///dendritic shaft+++GO:0043203///axon hillock+++GO:0044294///dendritic growth cone+++GO:0044297///cell body+++GO:0044307///dendritic branch+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite+++GO:0097442///CA3 pyramidal cell dendrite+++GO:0150001///primary dendrite+++GO:0150002///distal dendrite+++GO:0150014///apical distal dendrite+++GO:1902737///dendritic filopodium+++GO:1990635///proximal dendrite+++GO:1990769///proximal neuron projection GO:0002162///dystroglycan binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0019901///protein kinase binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007409///axonogenesis+++GO:0016358///dendrite development+++GO:0021954///central nervous system neuron development+++GO:0030010///establishment of cell polarity+++GO:0030517///negative regulation of axon extension+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031175///neuron projection development+++GO:0032880///regulation of protein localization+++GO:0071310///cellular response to organic substance+++GO:1901953///positive regulation of anterograde dense core granule transport+++GO:1902513///regulation of organelle transport along microtubule+++GO:1903744///positive regulation of anterograde synaptic vesicle transport+++GO:1903827///regulation of cellular protein localization+++GO:1904527///negative regulation of microtubule binding+++GO:2000575///negative regulation of microtubule motor activity 17758 17758 'Map4' mRNA 3918.22 3770.84 3905.1 36.63 34.38 38.33 42.06 38.46 40.73 36.44666667 40.41666667 5122.82 4599.71 4801.98 3864.72 4841.503333 2.68E-06 0.310904284 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005930///axoneme+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007052///mitotic spindle organization+++GO:0021954///central nervous system neuron development+++GO:0031175///neuron projection development+++GO:0051012///microtubule sliding+++GO:0051294///establishment of spindle orientation+++GO:0051301///cell division+++GO:1902856///negative regulation of non-motile cilium assembly 17760 17760 'Map6' mRNA 372 398 408 8.3 8.37 9.66 10.56 11.03 10.75 8.776666667 10.78 559 555 552 392.6666667 555.3333333 9.18E-05 0.486762579 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005801///cis-Golgi network+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0099503///secretory vesicle+++GO:1904115///axon cytoplasm GO:0005516///calmodulin binding+++GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0019896///axonal transport of mitochondrion+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0032418///lysosome localization+++GO:0048813///dendrite morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0070507///regulation of microtubule cytoskeleton organization 17761 17761 'Map7' mRNA 971 1014 952 13.43 14.73 14.33 7.14 6.86 6.15 14.16333333 6.716666667 595 530 497 979 540.6666667 5.10E-18 -0.869068961 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0000902///cell morphogenesis+++GO:0001578///microtubule bundle formation+++GO:0006687///glycosphingolipid metabolic process+++GO:0006970///response to osmotic stress+++GO:0006997///nucleus organization+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0008283///cell proliferation+++GO:0009566///fertilization+++GO:0032526///response to retinoic acid+++GO:0033327///Leydig cell differentiation+++GO:0035265///organ growth+++GO:0048872///homeostasis of number of cells+++GO:0060009///Sertoli cell development+++GO:0072659///protein localization to plasma membrane 17762 17762 'Mapt' mRNA 969 907 935 9.81 8.91 9.96 4.47 4.2 4.77 9.56 4.48 530 492 526 937 516 5.36E-18 -0.873731808 04010///MAPK signaling pathway+++05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005930///axoneme+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030673///axolemma+++GO:0034399///nuclear periphery+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0044304///main axon+++GO:0045121///membrane raft+++GO:0045298///tubulin complex+++GO:0097386///glial cell projection+++GO:0097418///neurofibrillary tangle GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031072///heat shock protein binding+++GO:0034185///apolipoprotein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding+++GO:0051721///protein phosphatase 2A binding+++GO:0051879///Hsp90 protein binding+++GO:0071813///lipoprotein particle binding+++GO:0099609///microtubule lateral binding GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0006915///apoptotic process+++GO:0007409///axonogenesis+++GO:0007416///synapse assembly+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0007628///adult walking behavior+++GO:0008088///axo-dendritic transport+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0010033///response to organic substance+++GO:0010288///response to lead ion+++GO:0010506///regulation of autophagy+++GO:0010629///negative regulation of gene expression+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0010976///positive regulation of neuron projection development+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031175///neuron projection development+++GO:0032387///negative regulation of intracellular transport+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033673///negative regulation of kinase activity+++GO:0045773///positive regulation of axon extension+++GO:0046785///microtubule polymerization+++GO:0047497///mitochondrion transport along microtubule+++GO:0048312///intracellular distribution of mitochondria+++GO:0048675///axon extension+++GO:0050808///synapse organization+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051028///mRNA transport+++GO:0051258///protein polymerization+++GO:0051260///protein homooligomerization+++GO:0060632///regulation of microtubule-based movement+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0090258///negative regulation of mitochondrial fission+++GO:0097435///supramolecular fiber organization+++GO:1900034///regulation of cellular response to heat+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1901216///positive regulation of neuron death+++GO:1902474///positive regulation of protein localization to synapse+++GO:1903748///negative regulation of establishment of protein localization to mitochondrion+++GO:1903829///positive regulation of cellular protein localization+++GO:1904428///negative regulation of tubulin deacetylation+++GO:1990000///amyloid fibril formation+++GO:2001020///regulation of response to DNA damage stimulus 17763 17763 'Mtcp1' mRNA 67.18 82.11 73.98 2.4 2.89 2.8 2.09 1.63 2 2.696666667 1.906666667 67.31 51.1 62.39 74.42333333 60.26666667 0.372267058 -0.315719829 04151///PI3K-Akt signaling pathway GO:0005739///mitochondrion+++GO:0032991///protein-containing complex GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity 17764 17764 'Mtf1' mRNA 604.24 551.9 455.65 4.17 3.74 3.34 2.68 2.52 2.68 3.75 2.626666667 447.26 411.14 432.99 537.2633333 430.4633333 0.012595173 -0.327911818 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035035///histone acetyltransferase binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006979///response to oxidative stress+++GO:0007417///central nervous system development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046686///response to cadmium ion+++GO:0071294///cellular response to zinc ion+++GO:1990079///cartilage homeostasis" 17765 17765 'Mtf2' mRNA 1230 1357 1300 16.14 17.36 17.65 13.52 12.52 14.47 17.05 13.50333333 1248 1089 1235 1295.666667 1190.666667 0.178750299 -0.135186766 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0035098///ESC/E(Z) complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0061087///positive regulation of histone H3-K27 methylation+++GO:1990830///cellular response to leukemia inhibitory factor" 17766 17766 'Nudt1' mRNA 127 151 152 8.42 10.08 10.58 11.09 11.33 14.6 9.693333333 12.34 192 189 240 143.3333333 207 0.014957442 0.517046674 GO:0001669///acrosomal vesicle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane "GO:0003723///RNA binding+++GO:0003924///GTPase activity+++GO:0008413///8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity+++GO:0008828///dATP pyrophosphohydrolase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0030515///snoRNA binding+++GO:0035539///8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity+++GO:0036219///GTP diphosphatase activity+++GO:0046872///metal ion binding+++GO:0047693///ATP diphosphatase activity+++GO:0050072///m7G(5')pppN diphosphatase activity" GO:0006152///purine nucleoside catabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0006203///dGTP catabolic process+++GO:0006281///DNA repair+++GO:0007568///aging+++GO:0008584///male gonad development+++GO:0042262///DNA protection+++GO:0046061///dATP catabolic process+++GO:0046686///response to cadmium ion 17768 17768 'Mthfd2' mRNA 275 258 303 7.43 6.89 8.69 10.15 9.61 9.69 7.67 9.816666667 429 395 396 278.6666667 406.6666667 3.92E-04 0.529474848 00670///One carbon pool by folate+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0004486///methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity+++GO:0004487///methylenetetrahydrofolate dehydrogenase (NAD+) activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016787///hydrolase activity+++GO:0042301///phosphate ion binding GO:0006730///one-carbon metabolic process+++GO:0008152///metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0046653///tetrahydrofolate metabolic process 17769 17769 'Mthfr' mRNA 1085 1173 1121 9.52 10.13 10.42 9.55 8.98 9.15 10.02333333 9.226666667 1254 1156 1166 1126.333333 1192 0.517084113 0.069039602 00670///One carbon pool by folate+++01523///Antifolate resistance GO:0005829///cytosol+++GO:0045202///synapse GO:0003824///catalytic activity+++GO:0004489///methylenetetrahydrofolate reductase (NAD(P)H) activity+++GO:0016491///oxidoreductase activity+++GO:0044877///protein-containing complex binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0071949///FAD binding+++GO:0072341///modified amino acid binding GO:0001666///response to hypoxia+++GO:0001843///neural tube closure+++GO:0006555///methionine metabolic process+++GO:0008152///metabolic process+++GO:0009086///methionine biosynthetic process+++GO:0031060///regulation of histone methylation+++GO:0033274///response to vitamin B2+++GO:0035999///tetrahydrofolate interconversion+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0050667///homocysteine metabolic process+++GO:0051593///response to folic acid+++GO:0070555///response to interleukin-1+++GO:0070829///heterochromatin maintenance 17771 17771 'Tesmin' mRNA 2 2 1 0.05 0.05 0.03 0.26 0.2 0.3 0.043333333 0.253333333 12 9 13 1.666666667 11.33333333 0.015307393 2.759070979 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation" 17772 17772 'Mtm1' mRNA 296 309 273 4.76 4.9 4.67 5.76 6.81 5.78 4.776666667 6.116666667 410 475 399 292.6666667 428 1.80E-04 0.539406269 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030175///filopodium+++GO:0031674///I band+++GO:0042995///cell projection "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019215///intermediate filament binding+++GO:0035091///phosphatidylinositol binding+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity" GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016311///dephosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0044088///regulation of vacuole organization+++GO:0045109///intermediate filament organization+++GO:0046716///muscle cell cellular homeostasis+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048311///mitochondrion distribution+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070584///mitochondrion morphogenesis+++GO:1902902///negative regulation of autophagosome assembly 17775 17775 'Laptm4a' mRNA 5865 5590 3974 154.77 145.36 111.36 189.2 183.52 228 137.1633333 200.24 8238 7788 9593 5143 8539.666667 1.83E-05 0.72789268 04142///Lysosome GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane 17776 17776 'Mast2' mRNA 3347 3525 3254 32.39 33.62 33.91 10.95 10.52 10.37 33.30666667 10.61333333 1154 1031 1058 3375.333333 1081 6.16E-131 -1.654663566 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019902///phosphatase binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032655///regulation of interleukin-12 production+++GO:0035556///intracellular signal transduction+++GO:0048515///spermatid differentiation 17777 17777 'Mttp' mRNA 244.31 267.01 271 3.26 3.43 3.79 1.72 1.6 1.5 3.493333333 1.606666667 158 140 126 260.7733333 141.3333333 9.96E-07 -0.897749743 04975///Fat digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016323///basolateral plasma membrane+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0031982///vesicle+++GO:0043235///receptor complex GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005548///phospholipid transporter activity+++GO:0008289///lipid binding+++GO:0034185///apolipoprotein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0120014///intermembrane phospholipid transfer activity+++GO:0120019///intermembrane phosphotidylcholine transfer activity+++GO:0120020///intermembrane cholesterol transfer activity+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:1904121///phosphatidylethanolamine transporter activity GO:0006497///protein lipidation+++GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006869///lipid transport+++GO:0007623///circadian rhythm+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009306///protein secretion+++GO:0015914///phospholipid transport+++GO:0015918///sterol transport+++GO:0034197///triglyceride transport+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034377///plasma lipoprotein particle assembly+++GO:0042157///lipoprotein metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0042953///lipoprotein transport+++GO:0051592///response to calcium ion+++GO:0120009///intermembrane lipid transfer+++GO:1902389///ceramide 1-phosphate transport 17826 17826 'Fam89b' mRNA 1158 1134 1094 58.8 56.94 59.05 99.97 103.32 96.71 58.26333333 100 2259 2275 2111 1128.666667 2215 3.32E-38 0.961285847 GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0001222///transcription corepressor binding+++GO:0005515///protein binding GO:0030010///establishment of cell polarity+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060392///negative regulation of SMAD protein signal transduction 17827 17827 'Mtx1' mRNA 521 510 408 29.59 28.65 24.61 33.06 37.02 35.3 27.61666667 35.12666667 667 727 689 479.6666667 694.3333333 7.94E-06 0.526753108 GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007005///mitochondrion organization+++GO:0007595///lactation+++GO:0015031///protein transport 17828 17828 'Bloc1s5' mRNA 637 650 674 20.78 21.02 23.17 18.39 13.24 15.66 21.65666667 15.76333333 646 455 534 653.6666667 545 0.046078505 -0.278842296 GO:0030133///transport vesicle+++GO:0031083///BLOC-1 complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0008089///anterograde axonal transport+++GO:0010467///gene expression+++GO:0016192///vesicle-mediated transport+++GO:0031175///neuron projection development+++GO:0032402///melanosome transport+++GO:0032474///otolith morphogenesis+++GO:0035646///endosome to melanosome transport+++GO:0048066///developmental pigmentation+++GO:0048490///anterograde synaptic vesicle transport+++GO:0050942///positive regulation of pigment cell differentiation 17829 17829 'Muc1' mRNA 58 48 99 1.45 1.19 2.63 8.57 7.64 6.99 1.756666667 7.733333333 393 342 310 68.33333333 348.3333333 2.62E-22 2.323352103 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003712///transcription coregulator activity "GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0043618///regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0090240///positive regulation of histone H4 acetylation+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator" 17830 17830 'Prol1' mRNA 30 23 12 1.59 1.2 0.67 0.78 0.71 0.81 1.153333333 0.766666667 17 15 17 21.66666667 16.33333333 0.575953016 -0.407448722 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding 17831 17831 'Muc2' mRNA 51 43 43 0.19 0.16 0.17 0.03 0.04 0.04 0.173333333 0.036666667 10 11 12 45.66666667 11 2.48E-05 -2.064012411 05146///Amoebiasis+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0070701///mucus layer+++GO:0070702///inner mucus layer+++GO:0070703///outer mucus layer GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002064///epithelial cell development+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030336///negative regulation of cell migration+++GO:0043065///positive regulation of apoptotic process 17833 17833 'Muc5ac' mRNA 2 2 1 0.01 0.01 0.01 0.01 0 0 0.01 0.003333333 2 0 1 1.666666667 1 0.795568009 -0.750350036 04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0070701///mucus layer GO:0005515///protein binding GO:0036438///maintenance of lens transparency+++GO:0048015///phosphatidylinositol-mediated signaling 17836 17836 'Mug1' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0007566///embryo implantation+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 17841 17841 'Mup2' mRNA 1 0 1 0.09 0 0.09 0.08 0 0 0.06 0.026666667 1 0 0 0.666666667 0.333333333 0.860258084 -0.929065017 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0005009///insulin-activated receptor activity+++GO:0005549///odorant binding+++GO:0005550///pheromone binding+++GO:0036094///small molecule binding "GO:0006112///energy reserve metabolic process+++GO:0008150///biological_process+++GO:0009060///aerobic respiration+++GO:0010628///positive regulation of gene expression+++GO:0010888///negative regulation of lipid storage+++GO:0010907///positive regulation of glucose metabolic process+++GO:0031649///heat generation+++GO:0042593///glucose homeostasis+++GO:0045475///locomotor rhythm+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045834///positive regulation of lipid metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070584///mitochondrion morphogenesis+++GO:0071396///cellular response to lipid" 17844 17844 'Mup5' mRNA 5 4 2 0.38 0.3 0.16 0.07 0.14 0 0.28 0.07 1 2 0 3.666666667 1 0.344451252 -1.868967567 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0005009///insulin-activated receptor activity+++GO:0005549///odorant binding+++GO:0005550///pheromone binding+++GO:0036094///small molecule binding "GO:0006112///energy reserve metabolic process+++GO:0007610///behavior+++GO:0008150///biological_process+++GO:0009060///aerobic respiration+++GO:0010628///positive regulation of gene expression+++GO:0010888///negative regulation of lipid storage+++GO:0010907///positive regulation of glucose metabolic process+++GO:0031649///heat generation+++GO:0042593///glucose homeostasis+++GO:0045475///locomotor rhythm+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045834///positive regulation of lipid metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070584///mitochondrion morphogenesis+++GO:0071396///cellular response to lipid" 17846 17846 'Commd1' mRNA 1072.04 1131.06 1111.75 87.37 91.5 95.73 105 101.69 99.03 91.53333333 101.9066667 1469.31 1398.13 1336.07 1104.95 1401.17 1.34E-04 0.329906387 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0055037///recycling endosome "GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0019871///sodium channel inhibitor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0070300///phosphatidic acid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0006289///nucleotide-excision repair+++GO:0006878///cellular copper ion homeostasis+++GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034383///low-density lipoprotein particle clearance+++GO:0042632///cholesterol homeostasis+++GO:0048227///plasma membrane to endosome transport+++GO:0055070///copper ion homeostasis+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:1902072///negative regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:1902306///negative regulation of sodium ion transmembrane transport+++GO:1904109///positive regulation of cholesterol import+++GO:1905751///positive regulation of endosome to plasma membrane protein transport+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2000010///positive regulation of protein localization to cell surface 17847 17847 'Usp34' mRNA 1305.49 1268.48 1099.16 5.7 5.44 5.05 5.67 4.86 5.49 5.396666667 5.34 1490.35 1256.57 1407.86 1224.376667 1384.926667 0.076579341 0.167200927 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016579///protein deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway 17850 17850 'Mmut' mRNA 2011 2069 1926 29.7 30.04 30.17 23.54 25.79 23.64 29.97 24.32333333 1835 1964 1785 2002 1861.333333 0.169788528 -0.115632422 "00280///Valine, leucine and isoleucine degradation+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003824///catalytic activity+++GO:0003924///GTPase activity+++GO:0004494///methylmalonyl-CoA mutase activity+++GO:0016853///isomerase activity+++GO:0016866///intramolecular transferase activity+++GO:0031419///cobalamin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046906///tetrapyrrole binding+++GO:0072341///modified amino acid binding GO:0009791///post-embryonic development+++GO:0043547///positive regulation of GTPase activity+++GO:0050667///homocysteine metabolic process 17855 17855 'Mvk' mRNA 615 662 638 20.65 21.95 22.87 16.15 18.59 17.22 21.82333333 17.32 549 619 568 638.3333333 578.6666667 0.240285471 -0.152752084 00900///Terpenoid backbone biosynthesis+++04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003729///mRNA binding+++GO:0004496///mevalonate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1990825///sequence-specific mRNA binding "GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0019287///isopentenyl diphosphate biosynthetic process, mevalonate pathway+++GO:0050728///negative regulation of inflammatory response" 17859 17859 'Mxi1' mRNA 1041 1085 1084 24.15 24.88 27.15 16.93 14.28 14.62 25.39333333 15.27666667 825 679 693 1070 732.3333333 3.18E-08 -0.561626091 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001825///blastocyst formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 17863 17863 'Myb' mRNA 2 4 2 0.03 0.06 0.03 0.04 0.14 0.06 0.04 0.08 3 10 4 2.666666667 5.666666667 0.457340331 1.093006059 04151///PI3K-Akt signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0071987///WD40-repeat domain binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006816///calcium ion transport+++GO:0010468///regulation of gene expression+++GO:0017145///stem cell division+++GO:0030099///myeloid cell differentiation+++GO:0030183///B cell differentiation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045624///positive regulation of T-helper cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048566///embryonic digestive tract development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048872///homeostasis of number of cells+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0060252///positive regulation of glial cell proliferation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071300///cellular response to retinoic acid+++GO:0071354///cellular response to interleukin-6+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:1901533///negative regulation of hematopoietic progenitor cell differentiation+++GO:1904899///positive regulation of hepatic stellate cell proliferation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000491///positive regulation of hepatic stellate cell activation+++GO:2000845///positive regulation of testosterone secretion" 17864 17864 'Mybl1' mRNA 33 26.76 33.99 0.33 0.24 0.35 1.01 0.87 0.73 0.306666667 0.87 121.38 97 82 31.25 100.1266667 2.65E-07 1.688438724 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000278///mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990511///piRNA biosynthetic process" 17865 17865 'Mybl2' mRNA 104 116 99 1.52 1.66 1.54 1.4 1.29 1.55 1.573333333 1.413333333 111 99 118 106.3333333 109.3333333 0.925309313 0.029721535 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031523///Myb complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000278///mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090307///mitotic spindle assembly+++GO:1990830///cellular response to leukemia inhibitory factor" 17869 17869 'Myc' mRNA 60 49 46 1.4 1.13 1.14 12.79 15.07 12.59 1.223333333 13.48333333 631 726 601 51.66666667 652.6666667 3.18E-93 3.650201572 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04110///Cell cycle+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04919///Thyroid hormone signaling pathway+++05132///Salmonella infection+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05213///Endometrial cancer+++05216///Thyroid cancer+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0016604///nuclear body+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000320///re-entry into mitotic cell cycle+++GO:0001541///ovarian follicle development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001783///B cell apoptotic process+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002082///regulation of oxidative phosphorylation+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0006006///glucose metabolic process+++GO:0006338///chromatin remodeling+++GO:0006351///transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006848///pyruvate transport+++GO:0006865///amino acid transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009314///response to radiation+++GO:0009611///response to wounding+++GO:0009812///flavonoid metabolic process+++GO:0010332///response to gamma radiation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016055///Wnt signaling pathway+++GO:0016485///protein processing+++GO:0019087///transformation of host cell by virus+++GO:0021854///hypothalamus development+++GO:0030728///ovulation+++GO:0032091///negative regulation of protein binding+++GO:0032204///regulation of telomere maintenance+++GO:0032355///response to estradiol+++GO:0032869///cellular response to insulin stimulus+++GO:0032986///protein-DNA complex disassembly+++GO:0035457///cellular response to interferon-alpha+++GO:0035690///cellular response to drug+++GO:0035914///skeletal muscle cell differentiation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042474///middle ear morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043279///response to alkaloid+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043473///pigmentation+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0044337///canonical Wnt signaling pathway involved in positive regulation of apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0044752///response to human chorionic gonadotropin+++GO:0045023///G0 to G1 transition+++GO:0045471///response to ethanol+++GO:0045656///negative regulation of monocyte differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045821///positive regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046325///negative regulation of glucose import+++GO:0046722///lactic acid secretion+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048705///skeletal system morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0051276///chromosome organization+++GO:0051726///regulation of cell cycle+++GO:0051782///negative regulation of cell division+++GO:0051973///positive regulation of telomerase activity+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060548///negative regulation of cell death+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0071322///cellular response to carbohydrate stimulus+++GO:0071345///cellular response to cytokine stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071378///cellular response to growth hormone stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071409///cellular response to cycloheximide+++GO:0071456///cellular response to hypoxia+++GO:0071464///cellular response to hydrostatic pressure+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071966///fungal-type cell wall polysaccharide metabolic process+++GO:0090096///positive regulation of metanephric cap mesenchymal cell proliferation+++GO:0097421///liver regeneration+++GO:1901857///positive regulation of cellular respiration+++GO:1903841///cellular response to arsenite(3-)+++GO:1903862///positive regulation of oxidative phosphorylation+++GO:1904385///cellular response to angiotensin+++GO:1904586///cellular response to putrescine+++GO:1904620///cellular response to dimethyl sulfoxide+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:1904672///regulation of somatic stem cell population maintenance+++GO:1905643///positive regulation of DNA methylation+++GO:1990646///cellular response to prolactin+++GO:1990858///cellular response to lectin+++GO:1990859///cellular response to endothelin+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:2001171///positive regulation of ATP biosynthetic process+++GO:2001235///positive regulation of apoptotic signaling pathway" 17872 17872 'Ppp1r15a' mRNA 1445 1433 1576 34.72 33.91 40.17 34.01 37.1 34.04 36.26666667 35.05 1628 1734 1577 1484.666667 1646.333333 0.194706231 0.134864555 04141///Protein processing in endoplasmic reticulum GO:0000164///protein phosphatase type 1 complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008157///protein phosphatase 1 binding+++GO:0019888///protein phosphatase regulator activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010955///negative regulation of protein processing+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0036496///regulation of translational initiation by eIF2 alpha dephosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045765///regulation of angiogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0060548///negative regulation of cell death+++GO:0060734///regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0070972///protein localization to endoplasmic reticulum+++GO:1902310///positive regulation of peptidyl-serine dephosphorylation+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:1903917///positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 17873 17873 'Gadd45b' mRNA 395 431 369 18.97 20.43 18.8 50.03 49.02 51.78 19.4 50.27666667 1196 1143 1197 398.3333333 1178.666667 5.74E-59 1.555005443 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0000185///activation of MAPKKK activity+++GO:0000186///activation of MAPKK activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0051726///regulation of cell cycle+++GO:1900745///positive regulation of p38MAPK cascade 17874 17874 'Myd88' mRNA 371 418 338 10.94 12.15 10.58 32.2 35.04 37.94 11.22333333 35.06 1255 1333 1431 375.6666667 1339.666667 1.45E-69 1.826226265 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0032991///protein-containing complex GO:0003953///NAD+ nucleosidase activity+++GO:0005102///signaling receptor binding+++GO:0005121///Toll binding+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0035325///Toll-like receptor binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0070976///TIR domain binding GO:0002238///response to molecule of fungal origin+++GO:0002269///leukocyte activation involved in inflammatory response+++GO:0002283///neutrophil activation involved in immune response+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007254///JNK cascade+++GO:0008063///Toll signaling pathway+++GO:0009615///response to virus+++GO:0009682///induced systemic resistance+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0016064///immunoglobulin mediated immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032481///positive regulation of type I interferon production+++GO:0032494///response to peptidoglycan+++GO:0032496///response to lipopolysaccharide+++GO:0032606///type I interferon production+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032747///positive regulation of interleukin-23 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034158///toll-like receptor 8 signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0070944///neutrophil mediated killing of bacterium+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1902622///regulation of neutrophil migration+++GO:2000338///regulation of chemokine (C-X-C motif) ligand 1 production+++GO:2000341///regulation of chemokine (C-X-C motif) ligand 2 production 17876 17876 'Myef2' mRNA 1440.16 1417.91 1440.27 23.18 22.31 24.09 22.32 18.82 20.51 23.19333333 20.55 1553.81 1252.6 1393.9 1432.78 1400.103333 0.689233014 -0.048228619 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071014///post-mRNA release spliceosomal complex+++GO:1990904///ribonucleoprotein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000815///regulation of mRNA stability involved in response to oxidative stress 17877 17877 'Myf5' mRNA 0 1 1 0 0.03 0.03 0 0 0 0.02 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity" "GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0001756///somitogenesis+++GO:0001952///regulation of cell-matrix adhesion+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0035914///skeletal muscle cell differentiation+++GO:0043010///camera-type eye development+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048644///muscle organ morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0060415///muscle tissue morphogenesis" 17879 17879 'Myh1' mRNA 20.74 17.62 20.01 0.18 0.15 0.19 0.04 0.02 0.02 0.173333333 0.026666667 5.22 2 2 19.45666667 3.073333333 0.001769516 -2.68288554 GO:0005737///cytoplasm+++GO:0005859///muscle myosin complex+++GO:0014704///intercalated disc+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0031672///A band+++GO:0032982///myosin filament+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0006936///muscle contraction 17880 17880 'Myh11' mRNA 54 36 45 0.42 0.31 0.4 0.12 0.25 0.29 0.376666667 0.22 17 31 40 45 29.33333333 0.207983056 -0.626270664 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005859///muscle myosin complex+++GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0030485///smooth muscle contractile fiber+++GO:0032982///myosin filament+++GO:0042470///melanosome GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding GO:0006939///smooth muscle contraction+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0048251///elastic fiber assembly+++GO:0048739///cardiac muscle fiber development+++GO:0055013///cardiac muscle cell development 17882 17882 'Myh2' mRNA 7.21 15.47 8.98 0.06 0.13 0.08 0.14 0.14 0.13 0.09 0.136666667 18.78 18 16 10.55333333 17.59333333 0.305916202 0.788789045 GO:0005794///Golgi apparatus+++GO:0005826///actomyosin contractile ring+++GO:0005859///muscle myosin complex+++GO:0005911///cell-cell junction+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0031672///A band+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0001778///plasma membrane repair+++GO:0006936///muscle contraction+++GO:0014823///response to activity+++GO:0070252///actin-mediated cell contraction 17883 17883 'Myh3' mRNA 10 15 0 0.09 0.13 0 0.02 0 0.05 0.073333333 0.023333333 2 0 6 8.333333333 2.666666667 0.308906753 -1.619721429 GO:0005737///cytoplasm+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0032982///myosin filament+++GO:0043292///contractile fiber GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0046034///ATP metabolic process 17884 17884 'Myh4' mRNA 46.05 35 52.01 0.4 0.3 0.48 0.03 0 0 0.393333333 0.01 4 0 0 44.35333333 1.333333333 2.13E-08 -5.081140972 GO:0005737///cytoplasm+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0032982///myosin filament GO:0000166///nucleotide binding+++GO:0003725///double-stranded RNA binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0014823///response to activity+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0048741///skeletal muscle fiber development+++GO:0060297///regulation of sarcomere organization 17885 17885 'Myh8' mRNA 0 1.01 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.336666667 0 0.863090843 -0.97353728 GO:0005737///cytoplasm+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0032982///myosin filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0030049///muscle filament sliding+++GO:0046034///ATP metabolic process 17886 17886 'Myh9' mRNA 1285 1308 872 9.11 9.12 6.56 18.08 15.81 17.09 8.263333333 16.99333333 2937.07 2509 2689.81 1155 2711.96 2.68E-32 1.226268426 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0001772///immunological synapse+++GO:0001931///uropod+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005826///actomyosin contractile ring+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0008180///COP9 signalosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030863///cortical cytoskeleton+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0042641///actomyosin+++GO:0060473///cortical granule+++GO:0097513///myosin II filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019904///protein domain specific binding+++GO:0030898///actin-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043495///protein membrane anchor+++GO:0043531///ADP binding+++GO:0051015///actin filament binding "GO:0000212///meiotic spindle organization+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001768///establishment of T cell polarity+++GO:0001778///plasma membrane repair+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006911///phagocytosis, engulfment+++GO:0006928///movement of cell or subcellular component+++GO:0007155///cell adhesion+++GO:0007520///myoblast fusion+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0030041///actin filament polymerization+++GO:0030048///actin filament-based movement+++GO:0030220///platelet formation+++GO:0030224///monocyte differentiation+++GO:0031032///actomyosin structure organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032418///lysosome localization+++GO:0032506///cytokinetic process+++GO:0032796///uropod organization+++GO:0043534///blood vessel endothelial cell migration+++GO:0045055///regulated exocytosis+++GO:0051295///establishment of meiotic spindle localization+++GO:0051693///actin filament capping+++GO:0060471///cortical granule exocytosis+++GO:0098609///cell-cell adhesion+++GO:1903919///negative regulation of actin filament severing+++GO:1903923///positive regulation of protein processing in phagocytic vesicle+++GO:1905684///regulation of plasma membrane repair" 17888 17888 'Myh6' mRNA 22 12 13.02 0.19 0.1 0.12 0.04 0.03 0.09 0.136666667 0.053333333 5 4 11 15.67333333 6.666666667 0.144943118 -1.240656788 04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005859///muscle myosin complex+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0032982///myosin filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0030898///actin-dependent ATPase activity+++GO:0030899///calcium-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0001701///in utero embryonic development+++GO:0002026///regulation of the force of heart contraction+++GO:0002027///regulation of heart rate+++GO:0006936///muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007512///adult heart development+++GO:0007522///visceral muscle development+++GO:0008016///regulation of heart contraction+++GO:0008217///regulation of blood pressure+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0030048///actin filament-based movement+++GO:0030049///muscle filament sliding+++GO:0030239///myofibril assembly+++GO:0043462///regulation of ATPase activity+++GO:0045214///sarcomere organization+++GO:0046034///ATP metabolic process+++GO:0048739///cardiac muscle fiber development+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060420///regulation of heart growth 17896 17896 'Myl4' mRNA 242.48 208.95 224.65 1.55 1.99 1.94 2.73 2.26 2.29 1.826666667 2.426666667 234.94 216.49 286.63 225.36 246.02 0.618237419 0.114247554 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway GO:0016459///myosin complex+++GO:0031672///A band GO:0003785///actin monomer binding+++GO:0005509///calcium ion binding+++GO:0051015///actin filament binding GO:0002026///regulation of the force of heart contraction+++GO:0032781///positive regulation of ATPase activity+++GO:0060048///cardiac muscle contraction 17897 17897 'Myl3' mRNA 45 43 37 3.24 3.08 2.83 0.69 0.78 0.46 3.05 0.643333333 11 12 7 41.66666667 10 6.86E-05 -2.067821655 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0016459///myosin complex+++GO:0031672///A band+++GO:0031674///I band GO:0003774///motor activity+++GO:0003785///actin monomer binding+++GO:0005509///calcium ion binding GO:0002026///regulation of the force of heart contraction+++GO:0006942///regulation of striated muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction 17898 17898 'Myl7' mRNA 0 1 2 0 0.13 0.28 0 0.35 0 0.136666667 0.116666667 0 3 0 1 1 0.998591786 -0.020259541 04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection GO:0016459///myosin complex+++GO:0031672///A band+++GO:0043197///dendritic spine GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding 17901 17901 'Myl1' mRNA 5 8 9 0.41 0.66 0.75 0.07 0.2 0.22 0.606666667 0.163333333 1 2 3 7.333333333 2 0.146263911 -1.889438466 GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0043292///contractile fiber GO:0005509///calcium ion binding+++GO:0008307///structural constituent of muscle GO:0006936///muscle contraction+++GO:0060048///cardiac muscle contraction 17904 17904 'Myl6' mRNA 6866 6975 6712 680.81 685.71 707.33 1132.31 1202.71 1137.48 691.2833333 1157.5 12773 13197 12379 6851 12783 8.01E-60 0.888334706 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0016461///unconventional myosin complex GO:0003774///motor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0030898///actin-dependent ATPase activity GO:0006936///muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0030049///muscle filament sliding 17906 17906 'Myl2' mRNA 6 2 7 0.44 0.22 0.58 0.68 0.2 0.8 0.413333333 0.56 8 2 8 5 6 0.868082126 0.229725216 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030016///myofibril+++GO:0031672///A band+++GO:0043292///contractile fiber+++GO:0097512///cardiac myofibril GO:0003785///actin monomer binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0002026///regulation of the force of heart contraction+++GO:0003007///heart morphogenesis+++GO:0007507///heart development+++GO:0009791///post-embryonic development+++GO:0030308///negative regulation of cell growth+++GO:0042694///muscle cell fate specification+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0055003///cardiac myofibril assembly+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060047///heart contraction+++GO:0060048///cardiac muscle contraction+++GO:0098735///positive regulation of the force of heart contraction 17907 17907 'Mylpf' mRNA 29.48 33 45.77 3.04 3.28 5.12 1.63 2.34 1.82 3.813333333 1.93 18.45 24 18.55 36.08333333 20.33333333 0.100515182 -0.853252278 04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection GO:0016459///myosin complex GO:0005509///calcium ion binding+++GO:0008307///structural constituent of muscle+++GO:0046872///metal ion binding GO:0006955///immune response+++GO:0007519///skeletal muscle tissue development 17909 17909 'Myo10' mRNA 2494.63 2278.99 2191.49 19.6 17.51 18.38 12.87 13.19 13.65 18.49666667 13.23666667 1904.83 1855.71 1957.59 2321.703333 1906.043333 6.12E-05 -0.295587525 04666///Fc gamma R-mediated phagocytosis+++05130///Pathogenic Escherichia coli infection GO:0001726///ruffle+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031527///filopodium membrane+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body "GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0030507///spectrin binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding+++GO:0060002///plus-end directed microfilament motor activity" GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0048870///cell motility+++GO:0051489///regulation of filopodium assembly 17910 17910 'Myo15' mRNA 7185 7245 6307 35.74 35.08 33.04 2.5 3.07 2.64 34.62 2.736666667 564 623 561 6912.333333 582.6666667 0 -3.57720271 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0031982///vesicle+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0042995///cell projection+++GO:0098858///actin-based cell projection GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0030050///vesicle transport along actin filament+++GO:0042472///inner ear morphogenesis 17912 17912 'Myo1b' mRNA 370 393 386 3.98 4.15 4.44 4.65 3.77 4.64 4.19 4.353333333 494 392 475 383 453.6666667 0.120028284 0.230219152 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0010008///endosome membrane+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030175///filopodium+++GO:0031982///vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery "GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding" GO:0006892///post-Golgi vesicle-mediated transport+++GO:0007015///actin filament organization+++GO:0030048///actin filament-based movement+++GO:0030050///vesicle transport along actin filament+++GO:0033572///transferrin transport+++GO:0051017///actin filament bundle assembly 17913 17913 'Myo1c' mRNA 1386 1512.99 1361.43 13.94 14.97 14.53 23.54 24.93 23.19 14.48 23.88666667 2692 2786 2569 1420.14 2682.333333 3.41E-36 0.907451213 05130///Pathogenic Escherichia coli infection GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0016459///myosin complex+++GO:0016604///nuclear body+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031941///filamentous actin+++GO:0031982///vesicle+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0045335///phagocytic vesicle+++GO:0060171///stereocilium membrane GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005543///phospholipid binding+++GO:0008022///protein C-terminus binding+++GO:0030898///actin-dependent ATPase activity+++GO:0031267///small GTPase binding+++GO:0051015///actin filament binding GO:0006605///protein targeting+++GO:0006612///protein targeting to membrane+++GO:0007015///actin filament organization+++GO:0015031///protein transport+++GO:0030050///vesicle transport along actin filament+++GO:0030335///positive regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:0051028///mRNA transport+++GO:0071346///cellular response to interferon-gamma+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway+++GO:2000810///regulation of bicellular tight junction assembly 17916 17916 'Myo1f' mRNA 117 109 111 1.65 1.51 1.66 20.57 21.27 20.26 1.606666667 20.7 1677 1694 1600 112.3333333 1657 4.92E-243 3.871543989 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030864///cortical actin cytoskeleton+++GO:0031941///filamentous actin+++GO:0031982///vesicle GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0002446///neutrophil mediated immunity+++GO:0007015///actin filament organization+++GO:0007162///negative regulation of cell adhesion+++GO:0009617///response to bacterium+++GO:0030050///vesicle transport along actin filament+++GO:0030335///positive regulation of cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043312///neutrophil degranulation+++GO:0045088///regulation of innate immune response+++GO:0050830///defense response to Gram-positive bacterium 17918 17918 'Myo5a' mRNA 885.48 940.68 922.95 3.12 3.25 3.41 9.17 8.81 9 3.26 8.993333333 2565.45 2367.21 2425.45 916.37 2452.703333 7.52E-78 1.408292718 05130///Pathogenic Escherichia coli infection "GO:0001726///ruffle+++GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005790///smooth endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0005884///actin filament+++GO:0008021///synaptic vesicle+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0016461///unconventional myosin complex+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0032433///filopodium tip+++GO:0032593///insulin-responsive compartment+++GO:0042470///melanosome+++GO:0042641///actomyosin+++GO:0042642///actomyosin, myosin complex part+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex" GO:0000146///microfilament motor activity+++GO:0000149///SNARE binding+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0017075///syntaxin-1 binding+++GO:0019901///protein kinase binding+++GO:0030898///actin-dependent ATPase activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043008///ATP-dependent protein binding+++GO:0044877///protein-containing complex binding+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding+++GO:0097718///disordered domain specific binding "GO:0006582///melanin metabolic process+++GO:0006887///exocytosis+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0007015///actin filament organization+++GO:0007268///chemical synaptic transmission+++GO:0007601///visual perception+++GO:0014046///dopamine secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0017157///regulation of exocytosis+++GO:0030048///actin filament-based movement+++GO:0030050///vesicle transport along actin filament+++GO:0030073///insulin secretion+++GO:0030318///melanocyte differentiation+++GO:0031585///regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0031987///locomotion involved in locomotory behavior+++GO:0032252///secretory granule localization+++GO:0032400///melanosome localization+++GO:0032402///melanosome transport+++GO:0032869///cellular response to insulin stimulus+++GO:0033602///negative regulation of dopamine secretion+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042417///dopamine metabolic process+++GO:0042438///melanin biosynthetic process+++GO:0042476///odontogenesis+++GO:0042552///myelination+++GO:0042640///anagen+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0048820///hair follicle maturation+++GO:0050808///synapse organization+++GO:0050885///neuromuscular process controlling balance+++GO:0051643///endoplasmic reticulum localization+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0065003///protein-containing complex assembly+++GO:0072659///protein localization to plasma membrane+++GO:0099089///establishment of endoplasmic reticulum localization to postsynapse+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0099640///axo-dendritic protein transport+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1904960///positive regulation of cytochrome-c oxidase activity" 17919 17919 'Myo5b' mRNA 367 366 206 2.89 2.84 1.98 0.86 1.27 1.39 2.57 1.173333333 115 182 203 313 166.6666667 1.80E-04 -0.904797286 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045179///apical cortex+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098944///postsynaptic recycling endosome membrane+++GO:0098978///glutamatergic synapse GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0031267///small GTPase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0051015///actin filament binding "GO:0007015///actin filament organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016197///endosomal transport+++GO:0030050///vesicle transport along actin filament+++GO:0032880///regulation of protein localization+++GO:0045773///positive regulation of axon extension+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060997///dendritic spine morphogenesis+++GO:0099003///vesicle-mediated transport in synapse+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0099639///neurotransmitter receptor transport, endosome to plasma membrane+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903543///positive regulation of exosomal secretion" 17920 17920 'Myo6' mRNA 8961.69 9075.26 8734.49 68.7 70.18 71.84 28.94 25.61 28.2 70.24 27.58333333 4122.6 3539 3930.37 8923.813333 3863.99 5.92E-94 -1.220695081 05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection "GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005905///clathrin-coated pit+++GO:0012506///vesicle membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030136///clathrin-coated vesicle+++GO:0030139///endocytic vesicle+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0031941///filamentous actin+++GO:0031965///nuclear membrane+++GO:0031982///vesicle+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098683///cochlear hair cell ribbon synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098833///presynaptic endocytic zone+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse" GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding "GO:0006605///protein targeting+++GO:0006897///endocytosis+++GO:0007015///actin filament organization+++GO:0007268///chemical synaptic transmission+++GO:0007416///synapse assembly+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0014047///glutamate secretion+++GO:0015031///protein transport+++GO:0016358///dendrite development+++GO:0030050///vesicle transport along actin filament+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0042493///response to drug+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048167///regulation of synaptic plasticity+++GO:0048839///inner ear development+++GO:0051046///regulation of secretion+++GO:0071257///cellular response to electrical stimulus+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:2000300///regulation of synaptic vesicle exocytosis" 17921 17921 'Myo7a' mRNA 2837 2787 2685 20.52 19.82 20.59 4.43 4.43 4.27 20.31 4.376666667 697 680 655 2769.666667 677.3333333 1.31E-168 -2.043556079 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016324///apical plasma membrane+++GO:0016459///myosin complex+++GO:0030054///cell junction+++GO:0031477///myosin VII complex+++GO:0031982///vesicle+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0042470///melanosome+++GO:0045202///synapse+++GO:0120044///stereocilium base+++GO:1990435///upper tip-link density GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0019904///protein domain specific binding+++GO:0030507///spectrin binding+++GO:0030898///actin-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0051015///actin filament binding GO:0001845///phagolysosome assembly+++GO:0006886///intracellular protein transport+++GO:0006909///phagocytosis+++GO:0007015///actin filament organization+++GO:0007040///lysosome organization+++GO:0007423///sensory organ development+++GO:0007600///sensory perception+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0030030///cell projection organization+++GO:0030048///actin filament-based movement+++GO:0030050///vesicle transport along actin filament+++GO:0034613///cellular protein localization+++GO:0042472///inner ear morphogenesis+++GO:0042490///mechanoreceptor differentiation+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0048839///inner ear development+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0051875///pigment granule localization+++GO:0051904///pigment granule transport+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060113///inner ear receptor cell differentiation+++GO:0060122///inner ear receptor cell stereocilium organization 17922 17922 'Myo7b' mRNA 6 8 6 0.05 0.06 0.05 0 0.04 0.01 0.053333333 0.016666667 0 5 2 6.666666667 2.333333333 0.292729918 -1.509331454 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0090651///apical cytoplasm GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007423///sensory organ development+++GO:0007605///sensory perception of sound+++GO:0030050///vesicle transport along actin filament+++GO:0030154///cell differentiation+++GO:1904970///brush border assembly 17925 17925 'Myo9b' mRNA 1045 1041 944 7.56 7.28 7.23 8.69 8.31 8.46 7.356666667 8.486666667 1256 1215 1202 1010 1224.333333 0.001635884 0.267123835 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005938///cell cortex+++GO:0016459///myosin complex+++GO:0030027///lamellipodium+++GO:0032433///filopodium tip+++GO:0048471///perinuclear region of cytoplasm GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005096///GTPase activator activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0031267///small GTPase binding+++GO:0043008///ATP-dependent protein binding+++GO:0043531///ADP binding+++GO:0046872///metal ion binding+++GO:0048495///Roundabout binding+++GO:0051015///actin filament binding GO:0002548///monocyte chemotaxis+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0030010///establishment of cell polarity+++GO:0030048///actin filament-based movement+++GO:0033275///actin-myosin filament sliding+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035385///Roundabout signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048246///macrophage chemotaxis+++GO:0050790///regulation of catalytic activity+++GO:0072673///lamellipodium morphogenesis 17926 17926 'Myoc' mRNA 54 71 55 1.47 1.91 1.59 2.23 2.74 2.91 1.656666667 2.626666667 94 113 119 60 108.6666667 0.002938562 0.849610627 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033268///node of Ranvier+++GO:0035748///myelin sheath abaxonal region+++GO:0042995///cell projection+++GO:0043220///Schmidt-Lanterman incisure+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0097453///mesaxon GO:0001968///fibronectin binding+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0032027///myosin light chain binding+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0001952///regulation of cell-matrix adhesion+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014734///skeletal muscle hypertrophy+++GO:0022011///myelination in peripheral nervous system+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0038133///ERBB2-ERBB3 signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0051492///regulation of stress fiber assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0060348///bone development+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 17928 17928 'Myog' mRNA 1 2 2 0.04 0.08 0.08 0.03 0.04 0 0.066666667 0.023333333 1 1 0 1.666666667 0.666666667 0.643290081 -1.341249535 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0008285///negative regulation of cell proliferation+++GO:0010831///positive regulation of myotube differentiation+++GO:0014737///positive regulation of muscle atrophy+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0014878///response to electrical stimulus involved in regulation of muscle adaptation+++GO:0014891///striated muscle atrophy+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0014902///myotube differentiation+++GO:0030154///cell differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0042692///muscle cell differentiation+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045820///negative regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048741///skeletal muscle fiber development+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071285///cellular response to lithium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:1901739///regulation of myoblast fusion+++GO:1903862///positive regulation of oxidative phosphorylation" 17929 17929 'Myom1' mRNA 81 58 59 1.24 0.97 1.06 0.74 0.76 1.06 1.09 0.853333333 50 63 70 66 61 0.784026243 -0.121469033 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030017///sarcomere+++GO:0031430///M band+++GO:0032982///myosin filament GO:0005200///structural constituent of cytoskeleton+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding GO:0002074///extraocular skeletal muscle development+++GO:0006936///muscle contraction+++GO:0007010///cytoskeleton organization+++GO:0010628///positive regulation of gene expression+++GO:0010737///protein kinase A signaling+++GO:0050714///positive regulation of protein secretion 17930 17930 'Myom2' mRNA 5 2 4 0.05 0.02 0.04 0.05 0.05 0 0.036666667 0.033333333 5 5 0 3.666666667 3.333333333 0.932578938 -0.157838579 GO:0005856///cytoskeleton+++GO:0031430///M band GO:0005200///structural constituent of cytoskeleton+++GO:0019900///kinase binding+++GO:0051015///actin filament binding GO:0002074///extraocular skeletal muscle development+++GO:0006936///muscle contraction+++GO:0045214///sarcomere organization 17931 17931 'Ppp1r12a' mRNA 1668 1740 1357 15.33 15.61 13.21 14.09 12.69 13.56 14.71666667 13.44666667 1767 1558 1650 1588.333333 1658.333333 0.622813857 0.053960876 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04510///Focal adhesion+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05205///Proteoglycans in cancer GO:0000776///kinetochore+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0031672///A band+++GO:0043292///contractile fiber+++GO:0072357///PTW/PP1 phosphatase complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0019208///phosphatase regulator activity+++GO:0019901///protein kinase binding+++GO:0071889///14-3-3 protein binding GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0007098///centrosome cycle+++GO:0007165///signal transduction+++GO:0030155///regulation of cell adhesion+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0035508///positive regulation of myosin-light-chain-phosphatase activity+++GO:0035690///cellular response to drug+++GO:0043086///negative regulation of catalytic activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0071466///cellular response to xenobiotic stimulus 17932 17932 'Myt1' mRNA 150.54 135.38 159 1.3 1.16 1.48 0.21 0.23 0.19 1.313333333 0.21 28 30 23 148.3066667 27 2.05E-17 -2.469886608 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0001678///cellular glucose homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009791///post-embryonic development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0032350///regulation of hormone metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060539///diaphragm development+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus" 17933 17933 'Myt1l' mRNA 58.99 76 71 0.39 0.53 0.5 0.02 0.02 0.05 0.473333333 0.03 4 4 10 68.66333333 6 9.69E-12 -3.521854746 GO:0005634///nucleus+++GO:0005694///chromosome "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0046872///metal ion binding+++GO:0050897///cobalt ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment+++GO:0048665///neuron fate specification+++GO:0048666///neuron development" 17936 17936 'Nab1' mRNA 274 290 258 4.09 4.21 4.03 5.97 5.55 6.44 4.11 5.986666667 459 424 486 274 456.3333333 7.10E-08 0.725227849 GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding "GO:0001958///endochondral ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0014037///Schwann cell differentiation+++GO:0042552///myelination+++GO:0045682///regulation of epidermis development+++GO:0045892///negative regulation of transcription, DNA-templated" 17937 17937 'Nab2' mRNA 604 636 485 13.33 13.82 11.33 14.61 15.46 14.77 12.82666667 14.94666667 764 788 745 575 765.6666667 3.17E-04 0.406281155 GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding "GO:0001958///endochondral ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0014037///Schwann cell differentiation+++GO:0016480///negative regulation of transcription by RNA polymerase III+++GO:0042552///myelination+++GO:0045682///regulation of epidermis development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1902949///positive regulation of tau-protein kinase activity" 17938 17938 'Naca' mRNA 5515.41 5467.7 4838.88 230.07 221.8 218.78 294.71 297.27 286.36 223.55 292.78 6512 6270.46 6078.42 5273.996667 6286.96 1.32E-05 0.243635947 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005854///nascent polypeptide-associated complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0017025///TBP-class protein binding+++GO:0051082///unfolded protein binding "GO:0003231///cardiac ventricle development+++GO:0006612///protein targeting to membrane+++GO:0010664///negative regulation of striated muscle cell apoptotic process+++GO:0015031///protein transport+++GO:0042060///wound healing+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051451///myoblast migration+++GO:0061384///heart trabecula morphogenesis+++GO:1901227///negative regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:1901228///positive regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis" 17939 17939 'Naga' mRNA 1571 1452 1375 47.25 43.01 43.8 33.91 35.18 35.77 44.68666667 34.95333333 1291 1308 1315 1466 1304.666667 0.038048407 -0.178573733 00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++04142///Lysosome GO:0005737///cytoplasm+++GO:0005764///lysosome "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004557///alpha-galactosidase activity+++GO:0008456///alpha-N-acetylgalactosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0042803///protein homodimerization activity" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0016052///carbohydrate catabolic process+++GO:0016139///glycoside catabolic process+++GO:0019377///glycolipid catabolic process+++GO:0046477///glycosylceramide catabolic process 17940 17940 'Naip1' mRNA 61 57.38 45.82 0.65 0.56 0.54 0.04 0.12 0.07 0.583333333 0.076666667 5.12 12.38 7.08 54.73333333 8.193333333 6.43E-08 -2.766785671 04621///NOD-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0072557///IPAF inflammasome complex GO:0000166///nucleotide binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005524///ATP binding+++GO:0030414///peptidase inhibitor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0010466///negative regulation of peptidase activity+++GO:0016045///detection of bacterium+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0070269///pyroptosis+++GO:0071391///cellular response to estrogen stimulus 17948 17948 'Naip2' mRNA 17 13 9.06 0.19 0.14 0.11 2.36 1.73 2.06 0.146666667 2.05 242.93 174.39 205.29 13.02 207.5366667 1.49E-34 3.982343549 04621///NOD-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0072557///IPAF inflammasome complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0016045///detection of bacterium+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0070269///pyroptosis+++GO:0071391///cellular response to estrogen stimulus 17951 17951 'Naip5' mRNA 52.34 48.55 45.46 0.67 0.59 0.58 2.39 2.67 2.67 0.613333333 2.576666667 225.41 232.83 243.62 48.78333333 233.9533333 1.36E-24 2.261347341 04621///NOD-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0072557///IPAF inflammasome complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0016045///detection of bacterium+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035635///entry of bacterium into host cell+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0070269///pyroptosis 17952 17952 'Naip6' mRNA 24 19.62 14.07 0.19 0.15 0.12 0.81 0.49 0.66 0.153333333 0.653333333 117.72 69.36 93.74 19.23 93.60666667 1.29E-09 2.280324178 04621///NOD-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0072557///IPAF inflammasome complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0016045///detection of bacterium+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0070269///pyroptosis+++GO:0071391///cellular response to estrogen stimulus 17954 17954 'Nap1l2' mRNA 49 55 43 1.1 1.22 1.03 1.62 1.32 1.11 1.116666667 1.35 83 66 55 49 68 0.209225283 0.46197373 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0035066///positive regulation of histone acetylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:2000035///regulation of stem cell division+++GO:2000617///positive regulation of histone H3-K9 acetylation 17955 17955 'Nap1l4' mRNA 3722 3880 3858 91.05 93.46 99.82 87.85 80.63 80.94 94.77666667 83.14 4127 3714 3677.7 3820 3839.566667 0.943750036 -0.006629814 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003682///chromatin binding+++GO:0031491///nucleosome binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly 17957 17957 'Napb' mRNA 394 494 422 5.31 6.58 6.11 2.59 2.48 3.19 6 2.753333333 240 218 280 436.6666667 246 4.76E-08 -0.838743943 GO:0005774///vacuolar membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0043209///myelin sheath+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005483///soluble NSF attachment protein activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding "GO:0002090///regulation of receptor internalization+++GO:0006886///intracellular protein transport+++GO:0010807///regulation of synaptic vesicle priming+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032984///protein-containing complex disassembly+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035494///SNARE complex disassembly+++GO:0043462///regulation of ATPase activity+++GO:0048488///synaptic vesicle endocytosis" 17960 17960 'Nat1' mRNA 44 34 44 1.65 1.26 1.75 1.21 1.21 0.84 1.553333333 1.086666667 37 36 25 40.66666667 32.66666667 0.511291465 -0.332430246 00232///Caffeine metabolism+++00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004060///arylamine N-acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" 17961 17961 'Nat2' mRNA 126 96 89 4.62 3.7 3.79 5.54 3.93 4.04 4.036666667 4.503333333 157 118 116 103.6666667 130.3333333 0.252540772 0.318852012 00232///Caffeine metabolism+++00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004060///arylamine N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" 17965 17965 'Nbl1' mRNA 2790 2921 1098 90.8 93.74 37.9 50.86 100.69 82.49 74.14666667 78.01333333 1796 3477 2818 2269.666667 2697 0.696837118 0.264189255 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0016015///morphogen activity+++GO:0036122///BMP binding+++GO:0042802///identical protein binding+++GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0009887///animal organ morphogenesis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0045666///positive regulation of neuron differentiation+++GO:0048263///determination of dorsal identity+++GO:0048812///neuron projection morphogenesis+++GO:0090027///negative regulation of monocyte chemotaxis 17966 17966 'Nbr1' mRNA 3123 3313 3409 36.19 37.83 41.93 26.67 26.73 26.77 38.65 26.72333333 2650 2590 2572 3281.666667 2604 3.03E-06 -0.347751538 04137///Mitophagy - animal GO:0000407///phagophore assembly site+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0031410///cytoplasmic vesicle+++GO:0031430///M band+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding GO:0016236///macroautophagy+++GO:0030500///regulation of bone mineralization+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0045668///negative regulation of osteoblast differentiation 17967 17967 'Ncam1' mRNA 1494 1556 1393 13.19 13.69 12.96 5.99 5.05 5.5 13.28 5.513333333 795 659 706 1481 720 2.26E-33 -1.052267798 04514///Cell adhesion molecules+++05020///Prion disease GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0019902///phosphatase binding+++GO:0030275///LRR domain binding+++GO:0042802///identical protein binding GO:0001928///regulation of exocyst assembly+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007413///axonal fasciculation+++GO:0007568///aging+++GO:0007611///learning or memory+++GO:0009410///response to xenobiotic stimulus+++GO:0010288///response to lead ion+++GO:0021794///thalamus development+++GO:0031175///neuron projection development+++GO:0033555///multicellular organismal response to stress+++GO:0034109///homotypic cell-cell adhesion+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0048666///neuron development+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0051930///regulation of sensory perception of pain+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060548///negative regulation of cell death+++GO:0071679///commissural neuron axon guidance+++GO:2001260///regulation of semaphorin-plexin signaling pathway 17968 17968 'Ncam2' mRNA 38 41 25 0.4 0.42 0.22 0.06 0.02 0.05 0.346666667 0.043333333 7 2 6 34.66666667 5 1.85E-05 -2.800408456 04514///Cell adhesion molecules+++05020///Prion disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007413///axonal fasciculation+++GO:0007608///sensory perception of smell 17969 17969 'Ncf1' mRNA 205 277 255 4.17 5.54 5.5 41.73 44.05 45.71 5.07 43.83 2364 2436 2506 245.6666667 2435.333333 8.17E-223 3.297751176 04062///Chemokine signaling pathway+++04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++05020///Prion disease+++05140///Leishmaniasis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030425///dendrite+++GO:0043020///NADPH oxidase complex+++GO:0043025///neuronal cell body "GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0017124///SH3 domain binding+++GO:0035091///phosphatidylinositol binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0060090///molecular adaptor activity" "GO:0001878///response to yeast+++GO:0001909///leukocyte mediated cytotoxicity+++GO:0002679///respiratory burst involved in defense response+++GO:0006612///protein targeting to membrane+++GO:0006691///leukotriene metabolic process+++GO:0006742///NADP catabolic process+++GO:0006801///superoxide metabolic process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006968///cellular defense response+++GO:0008283///cell proliferation+++GO:0009617///response to bacterium+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0034614///cellular response to reactive oxygen species+++GO:0042554///superoxide anion generation+++GO:0042742///defense response to bacterium+++GO:0045730///respiratory burst+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0046330///positive regulation of JNK cascade+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0060264///regulation of respiratory burst involved in inflammatory response+++GO:0070946///neutrophil mediated killing of gram-positive bacterium+++GO:0070947///neutrophil mediated killing of fungus+++GO:0071276///cellular response to cadmium ion+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1903409///reactive oxygen species biosynthetic process" 17970 17970 'Ncf2' mRNA 286 301 387 6.48 6.73 9.18 25.32 25.03 25.2 7.463333333 25.18333333 1250 1197 1203 324.6666667 1216.666667 1.88E-50 1.887568506 04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04670///Leukocyte transendothelial migration+++05020///Prion disease+++05140///Leishmaniasis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043020///NADPH oxidase complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0031267///small GTPase binding GO:0006742///NADP catabolic process+++GO:0006801///superoxide metabolic process+++GO:0006909///phagocytosis+++GO:0009749///response to glucose+++GO:0014070///response to organic cyclic compound+++GO:0032496///response to lipopolysaccharide+++GO:0032870///cellular response to hormone stimulus+++GO:0042554///superoxide anion generation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045730///respiratory burst+++GO:0045777///positive regulation of blood pressure+++GO:0050790///regulation of catalytic activity 17972 17972 'Ncf4' mRNA 51 53 47 2.28 2.2 2.21 49.92 53.67 52.51 2.23 52.03333333 1277 1354 1299 50.33333333 1310 2.81E-209 4.692128838 04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04670///Leukocyte transendothelial migration+++05020///Prion disease+++05140///Leishmaniasis+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0043020///NADPH oxidase complex GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0060090///molecular adaptor activity GO:0006801///superoxide metabolic process+++GO:0006909///phagocytosis+++GO:0042554///superoxide anion generation+++GO:0045730///respiratory burst+++GO:0050790///regulation of catalytic activity 17973 17973 'Nck1' mRNA 812 812.64 770 18.4 17.83 18.1 19.71 20.62 18.56 18.11 19.63 997.19 1022 913 798.2133333 977.3966667 0.004270876 0.281329206 04012///ErbB signaling pathway+++04360///Axon guidance+++04660///T cell receptor signaling pathway+++05130///Pathogenic Escherichia coli infection GO:0000164///protein phosphatase type 1 complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0012506///vesicle membrane "GO:0004860///protein kinase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0030971///receptor tyrosine kinase binding+++GO:0035591///signaling adaptor activity+++GO:0046875///ephrin receptor binding+++GO:0071074///eukaryotic initiation factor eIF2 binding" "GO:0006417///regulation of translation+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0030032///lamellipodium assembly+++GO:0030334///regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0042102///positive regulation of T cell proliferation+++GO:0042110///T cell activation+++GO:0043086///negative regulation of catalytic activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048013///ephrin receptor signaling pathway+++GO:0051707///response to other organism+++GO:0060548///negative regulation of cell death+++GO:0070262///peptidyl-serine dephosphorylation+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903676///positive regulation of cap-dependent translational initiation+++GO:1903679///positive regulation of cap-independent translational initiation+++GO:1903898///negative regulation of PERK-mediated unfolded protein response+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 17974 17974 'Nck2' mRNA 550 405 491 11.12 7.94 10.66 7.23 4.9 6.58 9.906666667 6.236666667 404 268 364 482 345.3333333 0.004141416 -0.498405736 04012///ErbB signaling pathway+++04360///Axon guidance+++04361///Axon regeneration+++04660///T cell receptor signaling pathway+++05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0012506///vesicle membrane+++GO:0014069///postsynaptic density+++GO:0045202///synapse GO:0001784///phosphotyrosine residue binding+++GO:0003779///actin binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0035591///signaling adaptor activity+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding GO:0001771///immunological synapse formation+++GO:0006417///regulation of translation+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0016477///cell migration+++GO:0030032///lamellipodium assembly+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0042102///positive regulation of T cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048013///ephrin receptor signaling pathway+++GO:0051016///barbed-end actin filament capping+++GO:0051017///actin filament bundle assembly+++GO:0060996///dendritic spine development+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903898///negative regulation of PERK-mediated unfolded protein response+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 17975 17975 'Ncl' mRNA 4247 4447 4182 47.67 49.39 48.37 60.86 59.47 60.7 48.47666667 60.34333333 5670 5324 5491 4292 5495 6.32E-10 0.344493896 05130///Pathogenic Escherichia coli infection GO:0001650///fibrillar center+++GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0009986///cell surface+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0042134///rRNA primary transcript binding+++GO:0042162///telomeric DNA binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0043236///laminin binding+++GO:0043565///sequence-specific DNA binding+++GO:0044547///DNA topoisomerase binding+++GO:0048027///mRNA 5'-UTR binding+++GO:1990631///ErbB-4 class receptor binding "GO:0001525///angiogenesis+++GO:0006897///endocytosis+++GO:0017148///negative regulation of translation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000232///regulation of rRNA processing" 17977 17977 'Ncoa1' mRNA 782 808 843 6.71 6.97 7.8 4.56 4.1 4.22 7.16 4.293333333 613 530 551 811 564.6666667 1.04E-06 -0.537218827 04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway+++05200///Pathways in cancer+++05224///Breast cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016922///nuclear receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0019899///enzyme binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0033142///progesterone receptor binding+++GO:0035257///nuclear hormone receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046965///retinoid X receptor binding+++GO:0046983///protein dimerization activity+++GO:0047485///protein N-terminus binding" "GO:0000435///positive regulation of transcription from RNA polymerase II promoter by galactose+++GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007595///lactation+++GO:0008584///male gonad development+++GO:0009725///response to hormone+++GO:0021549///cerebellum development+++GO:0021766///hippocampus development+++GO:0021854///hypothalamus development+++GO:0021987///cerebral cortex development+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032570///response to progesterone+++GO:0032870///cellular response to hormone stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0044849///estrous cycle+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045925///positive regulation of female receptivity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060179///male mating behavior+++GO:0060713///labyrinthine layer morphogenesis+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:2001038///regulation of cellular response to drug+++GO:2001141///regulation of RNA biosynthetic process" 17978 17978 'Ncoa2' mRNA 1784 1670 1631 13.05 12.06 12.41 6.46 6.49 6.55 12.50666667 6.5 1122 1013 1067 1695 1067.333333 7.89E-18 -0.679430787 04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0048786///presynaptic active zone GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0033142///progesterone receptor binding+++GO:0035257///nuclear hormone receptor binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0046983///protein dimerization activity+++GO:0070182///DNA polymerase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007623///circadian rhythm+++GO:0010468///regulation of gene expression+++GO:0010906///regulation of glucose metabolic process+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0032570///response to progesterone+++GO:0032870///cellular response to hormone stimulus+++GO:0032922///circadian regulation of gene expression+++GO:0045475///locomotor rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045925///positive regulation of female receptivity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway" 17979 17979 'Ncoa3' mRNA 2449 2405 2600 17.13 16.54 19.3 16.57 17.64 17.13 17.65666667 17.11333333 2728 2836 2730 2484.666667 2764.666667 0.104734231 0.140104616 01522///Endocrine resistance+++04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway+++05200///Pathways in cancer+++05224///Breast cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031941///filamentous actin+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000166///nucleotide binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003924///GTPase activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0016922///nuclear receptor binding+++GO:0019901///protein kinase binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035257///nuclear hormone receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0050681///androgen receptor binding+++GO:0097718///disordered domain specific binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0010628///positive regulation of gene expression+++GO:0014041///regulation of neuron maturation+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0016573///histone acetylation+++GO:0021894///cerebral cortex GABAergic interneuron development+++GO:0022604///regulation of cell morphogenesis+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030307///positive regulation of cell growth+++GO:0030865///cortical cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0032870///cellular response to hormone stimulus+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033145///positive regulation of intracellular steroid hormone receptor signaling pathway+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035264///multicellular organism growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043697///cell dedifferentiation+++GO:0045048///protein insertion into ER membrane+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048589///developmental growth+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051932///synaptic transmission, GABAergic+++GO:0060068///vagina development+++GO:0060713///labyrinthine layer morphogenesis+++GO:0060744///mammary gland branching involved in thelarche+++GO:0071392///cellular response to estradiol stimulus+++GO:0072091///regulation of stem cell proliferation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902459///positive regulation of stem cell population maintenance+++GO:2000035///regulation of stem cell division+++GO:2000036///regulation of stem cell population maintenance+++GO:2000737///negative regulation of stem cell differentiation" 17984 17984 'Ndn' mRNA 1127 1145 1119 39.76 39.82 41.88 33.31 30.61 34.27 40.48666667 32.73 1085 973 1080 1130.333333 1046 0.209579575 -0.124629846 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0042995///cell projection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0003016///respiratory system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007409///axonogenesis+++GO:0007413///axonal fasciculation+++GO:0007417///central nervous system development+++GO:0007585///respiratory gaseous exchange+++GO:0008285///negative regulation of cell proliferation+++GO:0008347///glial cell migration+++GO:0009791///post-embryonic development+++GO:0019233///sensory perception of pain+++GO:0030182///neuron differentiation+++GO:0040008///regulation of growth+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048666///neuron development+++GO:0048675///axon extension+++GO:0048871///multicellular organismal homeostasis+++GO:0071514///genetic imprinting+++GO:0090312///positive regulation of protein deacetylation" 17986 17986 'Ndp' mRNA 272 261 288 8.01 7.58 9 3.28 3.62 3.44 8.196666667 3.446666667 128 138 130 273.6666667 132 3.24E-09 -1.065651324 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0042803///protein homodimerization activity "GO:0001890///placenta development+++GO:0016055///Wnt signaling pathway+++GO:0035426///extracellular matrix-cell signaling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0061299///retina vasculature morphogenesis in camera-type eye" 17988 17988 'Ndrg1' mRNA 13269 13548 13403 252.88 254.11 270.96 128.72 128.41 122.85 259.3166667 126.66 7771 7571 7181 13406.66667 7507.666667 1.18E-52 -0.849476732 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0098978///glutamatergic synapse GO:0008017///microtubule binding+++GO:0031267///small GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0045296///cadherin binding "GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0042127///regulation of cell proliferation+++GO:0045576///mast cell activation+++GO:0071456///cellular response to hypoxia+++GO:0099173///postsynapse organization" 17991 17991 'Ndufa2' mRNA 3152 3058 3540 399.69 386.11 476.49 347.57 405.53 395.26 420.7633333 382.7866667 3127 3546 3427 3250 3366.666667 0.778473552 0.03601329 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0001835///blastocyst hatching+++GO:0022900///electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly 17992 17992 'Ndufa4' mRNA 3707 3605 3847 634.62 617.46 699.3 836.68 919.97 866.41 650.46 874.3533333 5556 5926 5534 3719.666667 5672 8.85E-17 0.595309581 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0004129///cytochrome-c oxidase activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:1904960///positive regulation of cytochrome-c oxidase activity 17993 17993 'Ndufs4' mRNA 1258 1223 1214 48.3 46.31 49.45 53.44 57.91 58.52 48.02 56.62333333 1599 1691 1694 1231.666667 1661.333333 2.82E-07 0.420349728 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain "GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H" GO:0001932///regulation of protein phosphorylation+++GO:0003016///respiratory system process+++GO:0006099///tricarboxylic acid cycle+++GO:0006954///inflammatory response+++GO:0007420///brain development+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0007628///adult walking behavior+++GO:0014876///response to injury involved in regulation of muscle adaptation+++GO:0019933///cAMP-mediated signaling+++GO:0022900///electron transport chain+++GO:0022904///respiratory electron transport chain+++GO:0030534///adult behavior+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0036343///psychomotor behavior+++GO:0042417///dopamine metabolic process+++GO:0045087///innate immune response+++GO:0045333///cellular respiration+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050890///cognition+++GO:0051591///response to cAMP+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070997///neuron death+++GO:0071453///cellular response to oxygen levels+++GO:0072593///reactive oxygen species metabolic process 17995 17995 'Ndufv1' mRNA 3846 4064 3807 139.91 145.77 146.92 119.81 124.29 121.93 144.2 122.01 3784 3831 3726 3905.666667 3780.333333 0.426439626 -0.05837524 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070469///respiratory chain "GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0022900///electron transport chain+++GO:0042775///mitochondrial ATP synthesis coupled electron transport" 17996 17996 'Neb' mRNA 11 4 16 0.02 0.01 0.04 0.01 0.02 0 0.023333333 0.01 7 11 2 10.33333333 6.666666667 0.570018232 -0.662275224 GO:0005865///striated muscle thin filament+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0043292///contractile fiber GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0030832///regulation of actin filament length+++GO:0045214///sarcomere organization+++GO:0048747///muscle fiber development+++GO:0071691///cardiac muscle thin filament assembly 17997 17997 'Nedd1' mRNA 315 323 350 4.85 4.89 5.71 6.24 5.94 6.32 5.15 6.166666667 467 434 458 329.3333333 453 0.001297284 0.44533279 "GO:0000242///pericentriolar material+++GO:0000922///spindle pole+++GO:0000924///gamma-tubulin ring complex, centrosomal+++GO:0000931///gamma-tubulin large complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0036064///ciliary basal body+++GO:0045177///apical part of cell" GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0031109///microtubule polymerization or depolymerization+++GO:0051301///cell division+++GO:0070201///regulation of establishment of protein localization+++GO:0071539///protein localization to centrosome 17999 17999 'Nedd4' mRNA 11092 11575 11092 105.84 109 112.81 102.49 94.13 98.62 109.2166667 98.41333333 12162 10930 11393 11253 11495 0.820747739 0.017721204 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04530///Tight junction+++05169///Epstein-Barr virus infection GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016740///transferase activity+++GO:0019871///sodium channel inhibitor activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0043130///ubiquitin binding+++GO:0050815///phosphoserine residue binding+++GO:0050816///phosphothreonine residue binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070063///RNA polymerase binding+++GO:0070064///proline-rich region binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0002250///adaptive immune response+++GO:0003151///outflow tract morphogenesis+++GO:0003197///endocardial cushion development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006622///protein targeting to lysosome+++GO:0007041///lysosomal transport+++GO:0007399///nervous system development+++GO:0007528///neuromuscular junction development+++GO:0010766///negative regulation of sodium ion transport+++GO:0010768///negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016567///protein ubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031175///neuron projection development+++GO:0031623///receptor internalization+++GO:0032801///receptor catabolic process+++GO:0034644///cellular response to UV+++GO:0034765///regulation of ion transmembrane transport+++GO:0042110///T cell activation+++GO:0042391///regulation of membrane potential+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0044111///development involved in symbiotic interaction+++GO:0045732///positive regulation of protein catabolic process+++GO:0046755///viral budding+++GO:0046824///positive regulation of nucleocytoplasmic transport+++GO:0048514///blood vessel morphogenesis+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050807///regulation of synapse organization+++GO:0050847///progesterone receptor signaling pathway+++GO:0070534///protein K63-linked ubiquitination+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity" 18000 18000 'Septin2' mRNA 4354 4348 4615 74.67 73.38 84.05 111.96 96.23 108.24 77.36666667 105.4766667 7508 6284 7026 4439 6939.333333 8.45E-18 0.628780409 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis "GO:0000145///exocyst+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005826///actomyosin contractile ring+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0005938///cell cortex+++GO:0005940///septin ring+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031105///septin complex+++GO:0031514///motile cilium+++GO:0032153///cell division site+++GO:0032154///cleavage furrow+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045171///intercellular bridge+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060170///ciliary membrane+++GO:0097227///sperm annulus+++GO:0097730///non-motile cilium" GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030234///enzyme regulator activity+++GO:0042802///identical protein binding+++GO:0060090///molecular adaptor activity GO:0002036///regulation of L-glutamate import across plasma membrane+++GO:0007049///cell cycle+++GO:0007224///smoothened signaling pathway+++GO:0007283///spermatogenesis+++GO:0017157///regulation of exocytosis+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0032880///regulation of protein localization+++GO:0034613///cellular protein localization+++GO:0050790///regulation of catalytic activity+++GO:0051258///protein polymerization+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0061640///cytoskeleton-dependent cytokinesis 18002 18002 'Nedd8' mRNA 2176 2094 2041 291.79 279.81 290.53 326.12 374.99 342.42 287.3766667 347.8433333 2773 3098 2805 2103.666667 2892 3.73E-09 0.448606698 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008104///protein localization+++GO:0014070///response to organic cyclic compound+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0030162///regulation of proteolysis+++GO:0045116///protein neddylation 18003 18003 'Nedd9' mRNA 1204 1195 1262 14.75 14.37 16.39 11.19 11.34 10.57 15.17 11.03333333 1062 1051 971 1220.333333 1028 0.006911743 -0.261335053 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex GO:0005515///protein binding+++GO:1990782///protein tyrosine kinase binding GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0040008///regulation of growth+++GO:0051301///cell division+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0090527///actin filament reorganization+++GO:0090630///activation of GTPase activity+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 18004 18004 'Nek1' mRNA 1726 1595 1611 20.59 18.66 20.23 11.84 10.09 12.62 19.82666667 11.51666667 1096 979 1118 1644 1064.333333 4.70E-14 -0.640025072 GO:0000242///pericentriolar material+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding "GO:0001822///kidney development+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0010212///response to ionizing radiation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030030///cell projection organization+++GO:0035264///multicellular organism growth+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:2000001///regulation of DNA damage checkpoint" 18005 18005 'Nek2' mRNA 1813 1905 1709 29.89 31.06 29.91 4.71 4.64 5.11 30.28666667 4.82 331 318 346 1809 331.6666667 7.70E-165 -2.457969982 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000794///condensed nuclear chromosome+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0032991///protein-containing complex" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding+++GO:0046872///metal ion binding GO:0000070///mitotic sister chromatid segregation+++GO:0001824///blastocyst development+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0016310///phosphorylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0043392///negative regulation of DNA binding+++GO:0046602///regulation of mitotic centrosome separation+++GO:0046777///protein autophosphorylation+++GO:0051299///centrosome separation+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051973///positive regulation of telomerase activity+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0090307///mitotic spindle assembly+++GO:1903126///negative regulation of centriole-centriole cohesion+++GO:1904355///positive regulation of telomere capping 18007 18007 'Neo1' mRNA 675 738 620 4.87 5.24 4.75 5.11 5.07 4.84 4.953333333 5.006666667 814 789 749 677.6666667 784 0.063957961 0.200595708 04350///TGF-beta signaling pathway+++04360///Axon guidance+++04514///Cell adhesion molecules GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0097708///intracellular vesicle+++GO:0098797///plasma membrane protein complex GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0039706///co-receptor binding+++GO:0045296///cadherin binding+++GO:0070700///BMP receptor binding "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007520///myoblast fusion+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0048679///regulation of axon regeneration+++GO:0048681///negative regulation of axon regeneration+++GO:0050709///negative regulation of protein secretion+++GO:0055072///iron ion homeostasis+++GO:0098609///cell-cell adhesion+++GO:1901215///negative regulation of neuron death+++GO:2001222///regulation of neuron migration" 18008 18008 'Nes' mRNA 811 726 543 7.03 6.22 5.14 8.73 11.09 10.56 6.13 10.12666667 1150 1436 1355 693.3333333 1313.666667 2.19E-13 0.919074529 GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0045111///intermediate filament cytoskeleton GO:0005515///protein binding+++GO:0019215///intermediate filament binding+++GO:0031730///CCR5 chemokine receptor binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0030844///positive regulation of intermediate filament depolymerization+++GO:0031076///embryonic camera-type eye development+++GO:0032091///negative regulation of protein binding+++GO:0043086///negative regulation of catalytic activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048858///cell projection morphogenesis+++GO:0072089///stem cell proliferation+++GO:2000179///positive regulation of neural precursor cell proliferation 18010 18010 'Neu1' mRNA 1318 1236 1280 18.52 17.08 19.08 25.47 25.92 24.36 18.22666667 25.25 2087 2074 1933 1278 2031.333333 1.06E-16 0.655752246 00511///Other glycan degradation+++00600///Sphingolipid metabolism+++04142///Lysosome GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0043202///lysosomal lumen+++GO:0043231///intracellular membrane-bounded organelle "GO:0004308///exo-alpha-sialidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016997///alpha-sialidase activity+++GO:0052794///exo-alpha-(2->3)-sialidase activity+++GO:0052795///exo-alpha-(2->6)-sialidase activity+++GO:0052796///exo-alpha-(2->8)-sialidase activity" GO:0005975///carbohydrate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016042///lipid catabolic process+++GO:2000291///regulation of myoblast proliferation 18011 18011 'Neurl1a' mRNA 183 195 180 2.8 2.97 2.94 2.31 1.91 1.83 2.903333333 2.016666667 173 142 133 186 149.3333333 0.123774463 -0.329719124 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043202///lysosomal lumen+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite "GO:0004308///exo-alpha-sialidase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016997///alpha-sialidase activity+++GO:0045183///translation factor activity, non-nucleic acid binding+++GO:0046872///metal ion binding+++GO:0052794///exo-alpha-(2->3)-sialidase activity+++GO:0052795///exo-alpha-(2->6)-sialidase activity+++GO:0052796///exo-alpha-(2->8)-sialidase activity+++GO:0061630///ubiquitin protein ligase activity" GO:0005975///carbohydrate metabolic process+++GO:0006417///regulation of translation+++GO:0006513///protein monoubiquitination+++GO:0006629///lipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0007219///Notch signaling pathway+++GO:0007288///sperm axoneme assembly+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007519///skeletal muscle tissue development+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0009313///oligosaccharide catabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016042///lipid catabolic process+++GO:0016567///protein ubiquitination+++GO:0030317///flagellated sperm motility+++GO:0043065///positive regulation of apoptotic process+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0051491///positive regulation of filopodium assembly+++GO:0060999///positive regulation of dendritic spine development+++GO:0071230///cellular response to amino acid stimulus+++GO:0090129///positive regulation of synapse maturation+++GO:2000291///regulation of myoblast proliferation 18012 18012 'Neurod1' mRNA 3 0 1 0.07 0 0.02 0.02 0.08 0.06 0.03 0.053333333 1 4 3 1.333333333 2.666666667 0.669993744 0.998894333 04950///Maturity onset diabetes of the young GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003326///pancreatic A cell fate commitment+++GO:0003329///pancreatic PP cell fate commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006913///nucleocytoplasmic transport+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009749///response to glucose+++GO:0009952///anterior/posterior pattern specification+++GO:0021542///dentate gyrus development+++GO:0021549///cerebellum development+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030073///insulin secretion+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030902///hindbrain development+++GO:0031018///endocrine pancreas development+++GO:0035881///amacrine cell differentiation+++GO:0035883///enteroendocrine cell differentiation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0045165///cell fate commitment+++GO:0045597///positive regulation of cell differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048562///embryonic organ morphogenesis+++GO:0048666///neuron development+++GO:0048839///inner ear development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060730///regulation of intestinal epithelial structure maintenance+++GO:0071156///regulation of cell cycle arrest+++GO:0071333///cellular response to glucose stimulus+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process+++GO:2000679///positive regulation of transcription regulatory region DNA binding" 18014 18014 'Neurog1' mRNA 10 6 11 0.34 0.2 0.4 0.09 0.09 0.18 0.313333333 0.12 3 3 6 9 4 0.28474362 -1.18954974 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007356///thorax and anterior abdomen determination+++GO:0007399///nervous system development+++GO:0021559///trigeminal nerve development+++GO:0021650///vestibulocochlear nerve formation+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030432///peristalsis+++GO:0031223///auditory behavior+++GO:0031536///positive regulation of exit from mitosis+++GO:0035112///genitalia morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0045165///cell fate commitment+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048634///regulation of muscle organ development+++GO:0048806///genitalia development+++GO:0048839///inner ear development+++GO:0050885///neuromuscular process controlling balance+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0071626///mastication+++GO:0090102///cochlea development+++GO:0090103///cochlea morphogenesis+++GO:0097094///craniofacial suture morphogenesis+++GO:0098583///learned vocalization behavior+++GO:1901078///negative regulation of relaxation of muscle+++GO:1905747///negative regulation of saliva secretion+++GO:1905748///hard palate morphogenesis" 18015 18015 'Nf1' mRNA 620 608 663 2.27 2.17 2.6 1.82 1.72 1.94 2.346666667 1.826666667 547 494 564 630.3333333 535 0.047195427 -0.251392215 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0098793///presynapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0031210///phosphatidylcholine binding+++GO:0045545///syndecan binding "GO:0000165///MAPK cascade+++GO:0001649///osteoblast differentiation+++GO:0001656///metanephros development+++GO:0001666///response to hypoxia+++GO:0001889///liver development+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001952///regulation of cell-matrix adhesion+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0006469///negative regulation of protein kinase activity+++GO:0007154///cell communication+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007420///brain development+++GO:0007422///peripheral nervous system development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0008285///negative regulation of cell proliferation+++GO:0008542///visual learning+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010468///regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014044///Schwann cell development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016525///negative regulation of angiogenesis+++GO:0021510///spinal cord development+++GO:0021764///amygdala development+++GO:0021897///forebrain astrocyte development+++GO:0021915///neural tube development+++GO:0021987///cerebral cortex development+++GO:0022011///myelination in peripheral nervous system+++GO:0030036///actin cytoskeleton organization+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030325///adrenal gland development+++GO:0030336///negative regulation of cell migration+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0034605///cellular response to heat+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043065///positive regulation of apoptotic process+++GO:0043087///regulation of GTPase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043408///regulation of MAPK cascade+++GO:0043409///negative regulation of MAPK cascade+++GO:0043473///pigmentation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043535///regulation of blood vessel endothelial cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0045124///regulation of bone resorption+++GO:0045664///regulation of neuron differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045685///regulation of glial cell differentiation+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0045765///regulation of angiogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046929///negative regulation of neurotransmitter secretion+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048485///sympathetic nervous system development+++GO:0048593///camera-type eye morphogenesis+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0048745///smooth muscle tissue development+++GO:0048820///hair follicle maturation+++GO:0048844///artery morphogenesis+++GO:0048853///forebrain morphogenesis+++GO:0050890///cognition+++GO:0061534///gamma-aminobutyric acid secretion, neurotransmission+++GO:0061535///glutamate secretion, neurotransmission+++GO:0098597///observational learning+++GO:1900271///regulation of long-term synaptic potentiation+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand" 18016 18016 'Nf2' mRNA 2361 2344 2303 26.95 26.41 27.8 17.03 15.88 16.56 27.05333333 16.49 1707 1550 1610 2336 1622.333333 1.86E-14 -0.538789568 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species+++04530///Tight junction GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030864///cortical actin cytoskeleton+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding GO:0001707///mesoderm formation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007398///ectoderm development+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0014010///Schwann cell proliferation+++GO:0014013///regulation of gliogenesis+++GO:0021766///hippocampus development+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030036///actin cytoskeleton organization+++GO:0030308///negative regulation of cell growth+++GO:0031647///regulation of protein stability+++GO:0035330///regulation of hippo signaling+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042981///regulation of apoptotic process+++GO:0043409///negative regulation of MAPK cascade+++GO:0045216///cell-cell junction organization+++GO:0045597///positive regulation of cell differentiation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0050767///regulation of neurogenesis+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051726///regulation of cell cycle+++GO:0070306///lens fiber cell differentiation+++GO:0072091///regulation of stem cell proliferation+++GO:1900180///regulation of protein localization to nucleus+++GO:2000177///regulation of neural precursor cell proliferation 18018 18018 'Nfatc1' mRNA 1264 1300 1205 15.44 15.54 15.59 12.42 11.8 12.25 15.52333333 12.15666667 1183 1117 1138 1256.333333 1146 0.100416556 -0.143998623 04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04921///Oxytocin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05135///Yersinia infection+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05417///Lipid and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0001225///RNA polymerase II transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001816///cytokine production+++GO:0001837///epithelial to mesenchymal transition+++GO:0001946///lymphangiogenesis+++GO:0002337///B-1a B cell differentiation+++GO:0003170///heart valve development+++GO:0003176///aortic valve development+++GO:0003177///pulmonary valve development+++GO:0003179///heart valve morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003197///endocardial cushion development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006816///calcium ion transport+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0014883///transition between fast and slow fiber+++GO:0030316///osteoclast differentiation+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0035556///intracellular signal transduction+++GO:0042634///regulation of hair cycle+++GO:0044838///cell quiescence+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060412///ventricular septum morphogenesis+++GO:0060854///branching involved in lymph vessel morphogenesis+++GO:0061384///heart trabecula morphogenesis+++GO:1905064///negative regulation of vascular smooth muscle cell differentiation+++GO:1905314///semi-lunar valve development+++GO:2000647///negative regulation of stem cell proliferation" 18019 18019 'Nfatc2' mRNA 326 248 239 2.81 2.13 2.15 3.95 4.77 4.41 2.363333333 4.376666667 568 666 605 271 613 4.01E-16 1.169670299 04022///cGMP-PKG signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04921///Oxytocin signaling pathway+++05135///Yersinia infection+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019902///phosphatase binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001816///cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009410///response to xenobiotic stimulus+++GO:0010628///positive regulation of gene expression+++GO:0014904///myotube cell development+++GO:0016477///cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0042493///response to drug+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050853///B cell receptor signaling pathway+++GO:1901741///positive regulation of myoblast fusion+++GO:1905064///negative regulation of vascular smooth muscle cell differentiation" 18020 18020 'Nfatc2ip' mRNA 47 53 47 0.77 0.85 0.8 0.73 0.83 0.92 0.806666667 0.826666667 52 58 64 49 58 0.576908111 0.233743192 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0001816///cytokine production+++GO:0045944///positive regulation of transcription by RNA polymerase II 18021 18021 'Nfatc3' mRNA 449.04 380.79 303.2 4 3.31 2.87 3.72 2.72 3.67 3.393333333 3.37 482 342.93 461.38 377.6766667 428.77 0.361851123 0.174142138 04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04625///C-type lectin receptor signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04921///Oxytocin signaling pathway+++05135///Yersinia infection+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001816///cytokine production+++GO:0001974///blood vessel remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0014902///myotube differentiation+++GO:0014904///myotube cell development+++GO:0030217///T cell differentiation+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0045333///cellular respiration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048538///thymus development+++GO:0048741///skeletal muscle fiber development+++GO:0051145///smooth muscle cell differentiation+++GO:0055001///muscle cell development+++GO:0071277///cellular response to calcium ion+++GO:0071285///cellular response to lithium ion+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1905064///negative regulation of vascular smooth muscle cell differentiation+++GO:2001256///regulation of store-operated calcium entry" 18022 18022 'Nfe2' mRNA 534 474 483 18.81 16.52 18.1 8.57 9.85 11.82 17.81 10.08 287 318 375 497 326.6666667 2.17E-05 -0.616042708 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0032993///protein-DNA complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0047485///protein N-terminus binding+++GO:0050699///WW domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007267///cell-cell signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0030502///negative regulation of bone mineralization+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:0060716///labyrinthine layer blood vessel development+++GO:2000758///positive regulation of peptidyl-lysine acetylation" 18023 18023 'Nfe2l1' mRNA 3959 4018 3844 49.99 50.31 52.28 46.75 45.05 47.55 50.86 46.45 4251 4017 4207 3940.333333 4158.333333 0.336023703 0.065678722 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:1990841///promoter-specific chromatin binding" "GO:0000089///mitotic metaphase+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006749///glutathione metabolic process+++GO:0007088///regulation of mitotic nuclear division+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010468///regulation of gene expression+++GO:0010906///regulation of glucose metabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019725///cellular homeostasis+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021781///glial cell fate commitment+++GO:0030218///erythrocyte differentiation+++GO:0034599///cellular response to oxidative stress+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0042632///cholesterol homeostasis+++GO:0042883///cysteine transport+++GO:0045454///cell redox homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0055088///lipid homeostasis+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070417///cellular response to cold+++GO:0071280///cellular response to copper ion+++GO:0071397///cellular response to cholesterol+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:1901329///regulation of odontoblast differentiation+++GO:1903353///regulation of nucleus organization+++GO:1905897///regulation of response to endoplasmic reticulum stress" 18024 18024 'Nfe2l2' mRNA 1707 1895 1830 38.09 41.63 43.32 66.78 68.94 67.99 41.01333333 67.90333333 3442 3470 3393 1810.666667 3435 7.85E-38 0.911399974 04141///Protein processing in endoplasmic reticulum+++04212///Longevity regulating pathway - worm+++05012///Parkinson disease+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007568///aging+++GO:0010226///response to lithium ion+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0030194///positive regulation of blood coagulation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034599///cellular response to oxidative stress+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035690///cellular response to drug+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0036091///positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045454///cell redox homeostasis+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045995///regulation of embryonic development+++GO:0046223///aflatoxin catabolic process+++GO:0046326///positive regulation of glucose import+++GO:0060548///negative regulation of cell death+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071280///cellular response to copper ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071456///cellular response to hypoxia+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071498///cellular response to fluid shear stress+++GO:0071499///cellular response to laminar fluid shear stress+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1903788///positive regulation of glutathione biosynthetic process+++GO:1904385///cellular response to angiotensin+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:2000121///regulation of removal of superoxide radicals+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process" 18025 18025 'Nfe2l3' mRNA 40 25 37 0.87 0.54 0.86 1.25 1.05 1.35 0.756666667 1.216666667 66 54 69 34 63 0.02394311 0.872914074 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 18027 18027 'Nfia' mRNA 7491 7423 6458 41.12 40.07 37.83 20.29 20.65 20.51 39.67333333 20.48333333 4255 4230 4161 7124 4215.333333 5.77E-44 -0.766174177 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030054///cell junction "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding" "GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060074///synapse maturation+++GO:0072189///ureter development" 18028 18028 'Nfib' mRNA 4008 3953 4411 23.05 22.43 27.12 17.68 14.53 17.15 24.2 16.45333333 3522 2817 3303 4124 3214 2.73E-05 -0.37705567 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0044300///cerebellar mossy fiber "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002062///chondrocyte differentiation+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0010001///glial cell differentiation+++GO:0021740///principal sensory nucleus of trigeminal nerve development+++GO:0021960///anterior commissure morphogenesis+++GO:0030324///lung development+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0043392///negative regulation of DNA binding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060486///Clara cell differentiation+++GO:0060509///type I pneumocyte differentiation+++GO:0060510///type II pneumocyte differentiation+++GO:0060662///salivary gland cavitation+++GO:0060689///cell differentiation involved in salivary gland development+++GO:0061141///lung ciliated cell differentiation+++GO:0071679///commissural neuron axon guidance+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000791///negative regulation of mesenchymal cell proliferation involved in lung development+++GO:2000795///negative regulation of epithelial cell proliferation involved in lung morphogenesis" 18029 18029 'Nfic' mRNA 7395 7282 6300 62.05 59.99 56.15 60.26 54.47 57.46 59.39666667 57.39666667 8249 7280 7627 6992.333333 7718.666667 0.034969734 0.132510668 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18030 18030 'Nfil3' mRNA 157 190 179 4.45 5.24 5.35 8.76 10.44 10.42 5.013333333 9.873333333 354 413 412 175.3333333 393 9.55E-13 1.153694822 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001779///natural killer cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006955///immune response+++GO:0007623///circadian rhythm+++GO:0010628///positive regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0071353///cellular response to interleukin-4" 18032 18032 'Nfix' mRNA 7505.95 7316.21 4308.84 143.26 140.55 140.7 101.06 101.23 105.85 141.5033333 102.7133333 4013.92 4086.99 4276 6377 4125.636667 0.004973768 -0.627504212 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021549///cerebellum development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021707///cerebellar granule cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048708///astrocyte differentiation" 18033 18033 'Nfkb1' mRNA 496 495 412 6.47 6.36 5.72 7.89 7.75 8.57 6.183333333 8.07 694 667 733 467.6666667 698 3.81E-07 0.569041511 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001225///RNA polymerase II transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042805///actinin binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001818///negative regulation of cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010956///negative regulation of calcidiol 1-monooxygenase activity+++GO:0014070///response to organic cyclic compound+++GO:0032695///negative regulation of interleukin-12 production+++GO:0035994///response to muscle stretch+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048535///lymph node development+++GO:0050728///negative regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071316///cellular response to nicotine+++GO:0071322///cellular response to carbohydrate stimulus+++GO:0071345///cellular response to cytokine stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071359///cellular response to dsRNA+++GO:0071407///cellular response to organic cyclic compound+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0098586///cellular response to virus+++GO:1900127///positive regulation of hyaluronan biosynthetic process+++GO:1901653///cellular response to peptide+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904385///cellular response to angiotensin+++GO:1904630///cellular response to diterpene+++GO:1904632///cellular response to glucoside+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000630///positive regulation of miRNA metabolic process+++GO:2000637///positive regulation of gene silencing by miRNA" 18034 18034 'Nfkb2' mRNA 904.51 850.22 798.46 10.6 10.29 9.68 18.99 17.96 16.23 10.19 17.72666667 1569.67 1507.44 1299 851.0633333 1458.703333 1.79E-16 0.766478488 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++05134///Legionellosis+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05224///Breast cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033257///Bcl3/NF-kappaB2 complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002268///follicular dendritic cell differentiation+++GO:0002467///germinal center formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0030198///extracellular matrix organization+++GO:0032496///response to lipopolysaccharide+++GO:0034097///response to cytokine+++GO:0038061///NIK/NF-kappaB signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048535///lymph node development+++GO:0048536///spleen development" 18035 18035 'Nfkbia' mRNA 2356 2233 2136 87.51 81.78 84.17 126.53 127.08 127 84.48666667 126.87 3914 3836 3801 2241.666667 3850.333333 2.16E-36 0.769281011 04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04931///Insulin resistance+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05208///Chemical carcinogenesis - reactive oxygen species+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051059///NF-kappaB binding "GO:0006606///protein import into nucleus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0010468///regulation of gene expression+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010888///negative regulation of lipid storage+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035994///response to muscle stretch+++GO:0042127///regulation of cell proliferation+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0043330///response to exogenous dsRNA+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050729///positive regulation of inflammatory response+++GO:0070427///nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071216///cellular response to biotic stimulus+++GO:0071345///cellular response to cytokine stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound" 18036 18036 'Nfkbib' mRNA 967.32 968.33 911.85 41.51 40.81 41.46 46.05 45.58 44.31 41.26 45.31333333 1213.84 1180.65 1133.12 949.1666667 1175.87 6.15E-04 0.297763945 04062///Chemokine signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04722///Neurotrophin signaling pathway+++04920///Adipocytokine signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05162///Measles+++05164///Influenza A+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0071222///cellular response to lipopolysaccharide 18037 18037 'Nfkbie' mRNA 251 268 250 5.75 6.04 6.08 13.9 11.65 14.13 5.956666667 13.22666667 698 570 687 256.3333333 651.6666667 2.24E-25 1.333416069 04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04722///Neurotrophin signaling pathway+++04920///Adipocytokine signaling pathway+++05169///Epstein-Barr virus infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding "GO:0042942///D-serine transport+++GO:0045892///negative regulation of transcription, DNA-templated" 18038 18038 'Nfkbil1' mRNA 195 145.42 156.81 8.06 5.92 6.87 9.84 9.77 8.49 6.95 9.366666667 272.53 264.96 228.64 165.7433333 255.3766667 0.001385291 0.611373352 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0071222///cellular response to lipopolysaccharide 18039 18039 'Nefl' mRNA 3912 3961 3721 63.08 62.84 63.64 6.24 4.76 5.38 63.18666667 5.46 445 332 372 3864.666667 383 0 -3.348030927 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005883///neurofilament+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098981///cholinergic synapse+++GO:0099160///postsynaptic intermediate filament cytoskeleton+++GO:0099182///presynaptic intermediate filament cytoskeleton+++GO:1904115///axon cytoplasm "GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0044877///protein-containing complex binding+++GO:0099184///structural constituent of postsynaptic intermediate filament cytoskeleton" GO:0000226///microtubule cytoskeleton organization+++GO:0008089///anterograde axonal transport+++GO:0008090///retrograde axonal transport+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0014012///peripheral nervous system axon regeneration+++GO:0019896///axonal transport of mitochondrion+++GO:0021510///spinal cord development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0031133///regulation of axon diameter+++GO:0033693///neurofilament bundle assembly+++GO:0040011///locomotion+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045105///intermediate filament polymerization or depolymerization+++GO:0045109///intermediate filament organization+++GO:0045110///intermediate filament bundle assembly+++GO:0048812///neuron projection morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0051258///protein polymerization+++GO:0051412///response to corticosterone+++GO:0060052///neurofilament cytoskeleton organization+++GO:0060074///synapse maturation+++GO:0061564///axon development+++GO:0099185///postsynaptic intermediate filament cytoskeleton organization+++GO:1903935///response to sodium arsenite+++GO:1903937///response to acrylamide 18040 18040 'Nefm' mRNA 3630 3404 2954 61.42 56.68 53.02 5.13 5.24 5.42 57.04 5.263333333 349 348 357 3329.333333 351.3333333 0 -3.252969004 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005883///neurofilament+++GO:0014069///postsynaptic density+++GO:0030424///axon+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0045111///intermediate filament cytoskeleton+++GO:0097418///neurofibrillary tangle+++GO:0099160///postsynaptic intermediate filament cytoskeleton+++GO:0099182///presynaptic intermediate filament cytoskeleton GO:0005102///signaling receptor binding+++GO:0005198///structural molecule activity+++GO:0015643///toxic substance binding+++GO:0044877///protein-containing complex binding GO:0000226///microtubule cytoskeleton organization+++GO:0008088///axo-dendritic transport+++GO:0031133///regulation of axon diameter+++GO:0033693///neurofilament bundle assembly+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045105///intermediate filament polymerization or depolymerization+++GO:0045110///intermediate filament bundle assembly+++GO:0060052///neurofilament cytoskeleton organization 18041 18041 'Nfs1' mRNA 1408 1422 1355 39.02 38.81 39.79 33.35 32.78 32.6 39.20666667 32.91 1380 1324 1312 1395 1338.666667 0.44741694 -0.071231918 00730///Thiamine metabolism+++01240///Biosynthesis of cofactors+++04122///Sulfur relay system GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0031071///cysteine desulfurase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0016226///iron-sulfur cluster assembly+++GO:0018283///iron incorporation into metallo-sulfur cluster+++GO:0044571///[2Fe-2S] cluster assembly 18044 18044 'Nfya' mRNA 129 150 75 2.01 2.26 1.2 2.13 1.7 2.76 1.823333333 2.196666667 161 126 202 118 163 0.105415928 0.465386171 04612///Antigen processing and presentation+++05017///Spinocerebellar ataxia+++05152///Tuberculosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016602///CCAAT-binding factor complex+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:2000036///regulation of stem cell population maintenance+++GO:2000648///positive regulation of stem cell proliferation" 18045 18045 'Nfyb' mRNA 782.18 868.4 667.06 17.25 18.77 15.55 13.56 13.1 12.97 17.19 13.21 711.32 669.5 659.47 772.5466667 680.0966667 0.095333234 -0.192438901 04612///Antigen processing and presentation+++05152///Tuberculosis+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016602///CCAAT-binding factor complex+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0070491///repressing transcription factor binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor" 18046 18046 'Nfyc' mRNA 1361.59 1501.59 1540.95 40.77 44.41 48.29 42.59 42.03 41.87 44.49 42.16333333 1632.8 1547.54 1561.35 1468.043333 1580.563333 0.376016935 0.092318762 04612///Antigen processing and presentation+++05152///Tuberculosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016602///CCAAT-binding factor complex+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18049 18049 'Ngf' mRNA 65 53 24 3.36 2.63 1.44 0.87 1.37 1.81 2.476666667 1.35 17 28 35 47.33333333 26.66666667 0.111679387 -0.81983187 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04722///Neurotrophin signaling pathway+++04750///Inflammatory mediator regulation of TRP channels GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0008021///synaptic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031904///endosome lumen+++GO:0044306///neuron projection terminus GO:0004857///enzyme inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005163///nerve growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008289///lipid binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0030414///peptidase inhibitor activity+++GO:0038177///death receptor agonist activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007422///peripheral nervous system development+++GO:0007613///memory+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010466///negative regulation of peptidase activity+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0014042///positive regulation of neuron maturation+++GO:0019233///sensory perception of pain+++GO:0021675///nerve development+++GO:0030307///positive regulation of cell growth+++GO:0031175///neuron projection development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032092///positive regulation of protein binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038180///nerve growth factor signaling pathway+++GO:0043388///positive regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045773///positive regulation of axon extension+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048666///neuron development+++GO:0048672///positive regulation of collateral sprouting+++GO:0048812///neuron projection morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0051402///neuron apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071229///cellular response to acid chemical+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:2000648///positive regulation of stem cell proliferation+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process 18053 18053 'Ngfr' mRNA 37 33 16 0.59 0.52 0.27 2.3 1.61 1.99 0.46 1.966666667 166 113 139 28.66666667 139.3333333 9.09E-13 2.276029879 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04215///Apoptosis - multiple species+++04722///Neurotrophin signaling pathway+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030135///coated vesicle+++GO:0030426///growth cone+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045334///clathrin-coated endocytic vesicle GO:0001540///amyloid-beta binding+++GO:0005035///death receptor activity+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015026///coreceptor activity+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043121///neurotrophin binding+++GO:0044877///protein-containing complex binding+++GO:0048406///nerve growth factor binding+++GO:0070678///preprotein binding "GO:0001678///cellular glucose homeostasis+++GO:0006886///intracellular protein transport+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007623///circadian rhythm+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0010941///regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0016048///detection of temperature stimulus+++GO:0016525///negative regulation of angiogenesis+++GO:0019233///sensory perception of pain+++GO:0021675///nerve development+++GO:0030154///cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0031069///hair follicle morphogenesis+++GO:0031643///positive regulation of myelination+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0032922///circadian regulation of gene expression+++GO:0034599///cellular response to oxidative stress+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035907///dorsal aorta development+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042488///positive regulation of odontogenesis of dentin-containing tooth+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0045666///positive regulation of neuron differentiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048511///rhythmic process+++GO:0051402///neuron apoptotic process+++GO:0051799///negative regulation of hair follicle development+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051902///negative regulation of mitochondrial depolarization+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0061000///negative regulation of dendritic spine development+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901216///positive regulation of neuron death+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1904646///cellular response to amyloid-beta+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2001235///positive regulation of apoptotic signaling pathway" 18054 18054 'Ngp' mRNA 65 59 66 3.46 3.1 3.73 3.2 3.28 2.74 3.43 3.073333333 69 69 57 63.33333333 65 0.957164135 0.02341259 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0006952///defense response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016525///negative regulation of angiogenesis+++GO:1901491///negative regulation of lymphangiogenesis 18071 18071 'Nhlh1' mRNA 69 58 37 1.55 1.28 0.88 0.21 0.3 0.16 1.236666667 0.223333333 11 15 8 54.66666667 11.33333333 3.19E-06 -2.270677862 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009791///post-embryonic development+++GO:0021794///thalamus development+++GO:0030154///cell differentiation+++GO:0030901///midbrain development+++GO:0035264///multicellular organism growth+++GO:0045944///positive regulation of transcription by RNA polymerase II 18073 18073 'Nid1' mRNA 1034 1022 1061 9.07 8.82 9.87 15.97 13.45 14.31 9.253333333 14.57666667 2096 1724 1819 1039 1879.666667 1.87E-21 0.840274348 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071944///cell periphery GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0043236///laminin binding+++GO:0043237///laminin-1 binding+++GO:0043394///proteoglycan binding+++GO:0050840///extracellular matrix binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0032836///glomerular basement membrane development 18074 18074 'Nid2' mRNA 293.72 339.64 296.72 3.22 3.66 3.45 12.69 12 12.3 3.443333333 12.33 1333.72 1233.12 1252.23 310.0266667 1273.023333 2.75E-91 2.029441039 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion 18080 18080 'Nin' mRNA 2025 1985 1505 14.83 14.37 11.75 3.58 3.67 3.93 13.65 3.726666667 640 611 620 1838.333333 623.6666667 8.27E-59 -1.56581549 GO:0000242///pericentriolar material+++GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0044295///axonal growth cone+++GO:0045177///apical part of cell+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0097539///ciliary transition fiber+++GO:0120103///centriolar subdistal appendage GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019900///kinase binding+++GO:0051011///microtubule minus-end binding GO:0007052///mitotic spindle organization+++GO:0008104///protein localization+++GO:0010457///centriole-centriole cohesion+++GO:0021540///corpus callosum morphogenesis+++GO:0021957///corticospinal tract morphogenesis+++GO:0031116///positive regulation of microtubule polymerization+++GO:0034454///microtubule anchoring at centrosome+++GO:0045666///positive regulation of neuron differentiation+++GO:0048668///collateral sprouting+++GO:0050772///positive regulation of axonogenesis+++GO:0051642///centrosome localization+++GO:0090222///centrosome-templated microtubule nucleation+++GO:1904780///negative regulation of protein localization to centrosome 18081 18081 'Ninj1' mRNA 4046 4352 3983 217.95 231.59 227.64 301.55 299.08 302.82 225.7266667 301.15 6423 6212 6236 4127 6290.333333 7.74E-28 0.59674394 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031527///filopodium membrane+++GO:0045202///synapse+++GO:0097060///synaptic membrane GO:0001530///lipopolysaccharide binding+++GO:0098631///cell adhesion mediator activity+++GO:0098632///cell-cell adhesion mediator activity GO:0001525///angiogenesis+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007610///behavior+++GO:0012501///programmed cell death+++GO:0019835///cytolysis+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0042246///tissue regeneration+++GO:0042692///muscle cell differentiation+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0048246///macrophage chemotaxis+++GO:0050729///positive regulation of inflammatory response+++GO:0051260///protein homooligomerization+++GO:0070265///necrotic cell death+++GO:0090025///regulation of monocyte chemotaxis+++GO:1905351///pericyte cell migration+++GO:1990384///hyaloid vascular plexus regression+++GO:2001206///positive regulation of osteoclast development 18082 18082 'Nipsnap1' mRNA 951.47 920.44 999.81 25.97 24.54 29.63 20.67 18.53 19.96 26.71333333 19.72 883.19 767.6 826.89 957.24 825.8933333 0.035176687 -0.228250497 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0097060///synaptic membrane GO:0005515///protein binding+++GO:0042165///neurotransmitter binding GO:0019233///sensory perception of pain 18087 18087 'Nktr' mRNA 2728.31 2574.98 2496.3 17.19 16.23 16.76 14.65 13.51 15.07 16.72666667 14.41 2605.09 2358.08 2605.42 2599.863333 2522.863333 0.522178221 -0.055176077 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 18095 18095 'Nkx3-1' mRNA 61 90 66 1.06 1.55 1.22 0.08 0.12 0.16 1.276666667 0.12 5 8 10 72.33333333 7.666666667 9.92E-12 -3.244312186 05200///Pathways in cancer+++05215///Prostate cancer GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0046930///pore complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0090734///site of DNA damage+++GO:0097136///Bcl-2 family protein complex+++GO:0097144///BAX complex+++GO:0097145///BAK complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008289///lipid binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0015267///channel activity+++GO:0030284///estrogen receptor activity+++GO:0030331///estrogen receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding+++GO:0051400///BH domain binding+++GO:0051434///BH3 domain binding+++GO:0097162///MADS box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001541///ovarian follicle development+++GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001756///somitogenesis+++GO:0001764///neuron migration+++GO:0001776///leukocyte homeostasis+++GO:0001777///T cell homeostatic proliferation+++GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001822///kidney development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001974///blood vessel remodeling+++GO:0002262///myeloid cell homeostasis+++GO:0002352///B cell negative selection+++GO:0002358///B cell homeostatic proliferation+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006687///glycosphingolipid metabolic process+++GO:0006808///regulation of nitrogen utilization+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0007008///outer mitochondrial membrane organization+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0007431///salivary gland development+++GO:0007507///heart development+++GO:0007548///sex differentiation+++GO:0008053///mitochondrial fusion+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0008637///apoptotic mitochondrial changes+++GO:0009566///fertilization+++GO:0009611///response to wounding+++GO:0009636///response to toxic substance+++GO:0009651///response to salt stress+++GO:0009791///post-embryonic development+++GO:0010212///response to ionizing radiation+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010332///response to gamma radiation+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0010942///positive regulation of cell death+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0021854///hypothalamus development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030521///androgen receptor signaling pathway+++GO:0030850///prostate gland development+++GO:0031334///positive regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0032880///regulation of protein localization+++GO:0032976///release of matrix enzymes from mitochondria+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033574///response to testosterone+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0034644///cellular response to UV+++GO:0035108///limb morphogenesis+++GO:0035234///ectopic germ cell programmed cell death+++GO:0035260///internal genitalia morphogenesis+++GO:0035690///cellular response to drug+++GO:0035907///dorsal aorta development+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045136///development of secondary sexual characteristics+++GO:0045333///cellular respiration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046666///retinal cell programmed cell death+++GO:0048087///positive regulation of developmental pigmentation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048515///spermatid differentiation+++GO:0048597///post-embryonic camera-type eye morphogenesis+++GO:0048678///response to axon injury+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048872///homeostasis of number of cells+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060011///Sertoli cell proliferation+++GO:0060037///pharyngeal system development+++GO:0060041///retina development in camera-type eye+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060068///vagina development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070242///thymocyte apoptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:0071310///cellular response to organic substance+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071850///mitotic cell cycle arrest+++GO:0071899///negative regulation of estrogen receptor binding+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097296///activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0097435///supramolecular fiber organization+++GO:0098586///cellular response to virus+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:1902512///positive regulation of apoptotic DNA fragmentation+++GO:1990117///B cell receptor apoptotic signaling pathway+++GO:2000836///positive regulation of androgen secretion+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 18096 18096 'Nkx6-1' mRNA 3 6 3 0.1 0.19 0.1 0.11 0.09 0.11 0.13 0.103333333 4 3 4 4 3.666666667 0.936365601 -0.130025839 04950///Maturity onset diabetes of the young GO:0005634///nucleus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0003309///type B pancreatic cell differentiation+++GO:0003323///type B pancreatic cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0021953///central nervous system neuron differentiation+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030516///regulation of axon extension+++GO:0031018///endocrine pancreas development+++GO:0032024///positive regulation of insulin secretion+++GO:0035094///response to nicotine+++GO:0042493///response to drug+++GO:0044342///type B pancreatic cell proliferation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045686///negative regulation of glial cell differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0050796///regulation of insulin secretion+++GO:0071345///cellular response to cytokine stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:2001222///regulation of neuron migration" 18099 18099 'Nlk' mRNA 366 400 280 4.37 4.69 3.53 3.12 2.61 2.93 4.196666667 2.886666667 301 246 274 348.6666667 273.6666667 0.033240445 -0.356499807 04010///MAPK signaling pathway+++04068///FoxO signaling pathway+++04310///Wnt signaling pathway+++04520///Adherens junction GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042169///SH2 domain binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0042501///serine phosphorylation of STAT protein+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization" 18100 18100 'Mrpl40' mRNA 774.16 695.94 675 45.49 40.18 42.41 50.1 52.55 48.27 42.69333333 50.30666667 974 999.8 905.95 715.0333333 959.9166667 4.09E-05 0.414012889 GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function GO:0008150///biological_process 18101 18101 'Nmbr' mRNA 18 23 12 0.42 0.5 0.29 0.08 0.12 0.12 0.403333333 0.106666667 4 6 6 17.66666667 5.333333333 0.030201739 -1.726371034 04080///Neuroactive ligand-receptor interaction GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004946///bombesin receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0031989///bombesin receptor signaling pathway 18102 18102 'Nme1' mRNA 2336 2255 2401 150.15 143.41 163.95 210.68 224.91 213.31 152.5033333 216.3 3742 3896 3670 2330.666667 3769.333333 1.24E-20 0.680204149 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004536///deoxyribonuclease activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019215///intermediate filament binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding+++GO:0043024///ribosomal small subunit binding+++GO:0046872///metal ion binding GO:0002762///negative regulation of myeloid leukocyte differentiation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006231///dTMP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0006259///DNA metabolic process+++GO:0006897///endocytosis+++GO:0007399///nervous system development+++GO:0007595///lactation+++GO:0009117///nucleotide metabolic process+++GO:0010629///negative regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014075///response to amine+++GO:0016310///phosphorylation+++GO:0021766///hippocampus development+++GO:0030154///cell differentiation+++GO:0030879///mammary gland development+++GO:0033574///response to testosterone+++GO:0035690///cellular response to drug+++GO:0042493///response to drug+++GO:0043388///positive regulation of DNA binding+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051591///response to cAMP+++GO:0071333///cellular response to glucose stimulus+++GO:0071398///cellular response to fatty acid 18103 18103 'Nme2' mRNA 1522 1485 1418 129.86 124.59 126.83 270.54 283.71 282.9 127.0933333 279.05 3607 3664 3679 1475 3650 9.99E-90 1.296293939 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005882///intermediate filament+++GO:0005925///focal adhesion+++GO:0030027///lamellipodium+++GO:0031966///mitochondrial membrane+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0004673///protein histidine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019003///GDP binding+++GO:0019215///intermediate filament binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:1901363///heterocyclic compound binding "GO:0002762///negative regulation of myeloid leukocyte differentiation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006231///dTMP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0009117///nucleotide metabolic process+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018106///peptidyl-histidine phosphorylation+++GO:0034599///cellular response to oxidative stress+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045682///regulation of epidermis development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060416///response to growth hormone+++GO:0071333///cellular response to glucose stimulus+++GO:0071398///cellular response to fatty acid" 18104 18104 'Nqo1' mRNA 632.21 653.02 591.93 23.22 23.69 23.19 22.88 21.32 24.91 23.36666667 23.03666667 720.95 649.85 745.82 625.72 705.54 0.16838937 0.161247866 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003955///NAD(P)H dehydrogenase (quinone) activity+++GO:0004784///superoxide dismutase activity+++GO:0008753///NADPH dehydrogenase (quinone) activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0050136///NADH dehydrogenase (quinone) activity GO:0002931///response to ischemia+++GO:0006116///NADH oxidation+++GO:0006801///superoxide metabolic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0009743///response to carbohydrate+++GO:0010033///response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0014075///response to amine+++GO:0019430///removal of superoxide radicals+++GO:0032355///response to estradiol+++GO:0033574///response to testosterone+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043279///response to alkaloid+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0045471///response to ethanol+++GO:0051602///response to electrical stimulus+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070995///NADPH oxidation+++GO:0071248///cellular response to metal ion+++GO:1901698///response to nitrogen compound+++GO:1904772///response to tetrachloromethane+++GO:1904844///response to L-glutamine+++GO:1904880///response to hydrogen sulfide+++GO:1905395///response to flavonoid 18105 18105 'Nqo2' mRNA 595 601 649 9.24 9.19 10.4 13.8 12.85 11.91 9.61 12.85333333 1022 944 880 615 948.6666667 1.35E-08 0.610317411 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001512///dihydronicotinamide riboside quinone reductase activity+++GO:0003955///NAD(P)H dehydrogenase (quinone) activity+++GO:0008270///zinc ion binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0016661///oxidoreductase activity, acting on other nitrogenous compounds as donors+++GO:0031404///chloride ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0071949///FAD binding+++GO:1904408///melatonin binding+++GO:1905594///resveratrol binding" GO:0007613///memory+++GO:0022900///electron transport chain+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901662///quinone catabolic process+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000379///positive regulation of reactive oxygen species metabolic process 18106 18106 'Cd244a' mRNA 5 6 3 0.07 0.11 0.07 2.6 2.66 2.11 0.083333333 2.456666667 170 169 124 4.666666667 154.3333333 1.58E-26 5.038606298 04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042288///MHC class I protein binding "GO:0001773///myeloid dendritic cell activation+++GO:0002250///adaptive immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0045087///innate immune response+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0071663///positive regulation of granzyme B production+++GO:2000566///positive regulation of CD8-positive, alpha-beta T cell proliferation" 18107 18107 'Nmt1' mRNA 1224 1147 1462 23.34 21.99 31.81 44.1 38.24 40.04 25.71333333 40.79333333 2168 1878 1925 1277.666667 1990.333333 1.35E-08 0.619977338 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane "GO:0004379///glycylpeptide N-tetradecanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019107///myristoyltransferase activity" GO:0001701///in utero embryonic development+++GO:0006499///N-terminal protein myristoylation+++GO:0018008///N-terminal peptidyl-glycine N-myristoylation+++GO:0042180///cellular ketone metabolic process 18108 18108 'Nmt2' mRNA 281.29 186.9 203.59 3.4 2.22 2.62 4.63 4.69 4.58 2.746666667 4.633333333 441.48 436.57 422.36 223.9266667 433.47 1.05E-08 0.944453251 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane "GO:0004379///glycylpeptide N-tetradecanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006499///N-terminal protein myristoylation+++GO:0018008///N-terminal peptidyl-glycine N-myristoylation 18109 18109 'Mycn' mRNA 221 192 193 4.73 4.04 4.38 0.95 1.3 1.42 4.383333333 1.223333333 51 68 74 202 64.33333333 6.74E-13 -1.66004661 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001502///cartilage condensation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0030324///lung development+++GO:0042733///embryonic digit morphogenesis+++GO:0045607///regulation of inner ear auditory receptor cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 18111 18111 'Nnat' mRNA 889 896 777 43.63 43.31 40.31 20.85 20.69 20.82 42.41666667 20.78666667 479 471 472 854 474 1.65E-17 -0.858828858 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0009749///response to glucose+++GO:0032024///positive regulation of insulin secretion+++GO:0032880///regulation of protein localization 18113 18113 'Nnmt' mRNA 3 8 8 0.19 0.5 0.45 3.25 3.05 3.51 0.38 3.27 60 54 65 6.333333333 59.66666667 7.17E-10 3.221079396 00760///Nicotinate and nicotinamide metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008112///nicotinamide N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008170///N-methyltransferase activity+++GO:0016740///transferase activity GO:0006769///nicotinamide metabolic process+++GO:0010243///response to organonitrogen compound+++GO:0010967///regulation of polyamine biosynthetic process+++GO:0031060///regulation of histone methylation+++GO:0031100///animal organ regeneration+++GO:0032259///methylation+++GO:0042493///response to drug+++GO:0045722///positive regulation of gluconeogenesis+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0090312///positive regulation of protein deacetylation 18114 18114 'Rrp1' mRNA 5566 5595 5501 157.66 156.21 165.33 138.66 134.92 136.74 159.7333333 136.7733333 5625 5344 5370 5554 5446.333333 0.571536111 -0.040926247 "GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0030688///preribosome, small subunit precursor" GO:0006364///rRNA processing 18115 18115 'Nnt' mRNA 1557 1496 1498 23.18 21.91 23.65 21.48 20.75 21.61 22.91333333 21.28 1661 1567 1618 1517 1615.333333 0.39077625 0.078062592 00760///Nicotinate and nicotinamide metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008746///NAD(P)+ transhydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0050661///NADP binding+++GO:0051287///NAD binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006740///NADPH regeneration+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0032364///oxygen homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1902600///proton transmembrane transport+++GO:1903285///positive regulation of hydrogen peroxide catabolic process 18117 18117 'Emc8' mRNA 1516.61 1438.75 1554.24 16.52 15.41 17.96 13.45 14.55 13.7 16.63 13.9 1421.84 1502.6 1402.13 1503.2 1442.19 0.503800196 -0.073203205 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 18120 18120 'Mrpl49' mRNA 930 923 975 31.22 30.54 34.72 32.6 32.38 30.91 32.16 31.96333333 1116 1082 1024 942.6666667 1074 0.09110761 0.174240395 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 18121 18121 'Nog' mRNA 2 2 0 0.06 0.06 0 0.05 0.11 0.03 0.04 0.063333333 2 4 1 1.333333333 2.333333333 0.741082698 0.828150057 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0032991///protein-containing complex GO:0019955///cytokine binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001655///urogenital system development+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001706///endoderm formation+++GO:0001707///mesoderm formation+++GO:0001837///epithelial to mesenchymal transition+++GO:0001839///neural plate morphogenesis+++GO:0001843///neural tube closure+++GO:0003149///membranous septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007492///endoderm development+++GO:0007613///memory+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0008542///visual learning+++GO:0009953///dorsal/ventral pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0021510///spinal cord development+++GO:0021533///cell differentiation in hindbrain+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0030510///regulation of BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0042060///wound healing+++GO:0042474///middle ear morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0045596///negative regulation of cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048318///axial mesoderm development+++GO:0048570///notochord morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048762///mesenchymal cell differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060173///limb development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060302///negative regulation of cytokine activity+++GO:0060325///face morphogenesis+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060412///ventricular septum morphogenesis+++GO:0060425///lung morphogenesis+++GO:0060513///prostatic bud formation+++GO:0060676///ureteric bud formation+++GO:0060825///fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation+++GO:0061037///negative regulation of cartilage development+++GO:0061053///somite development+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0061384///heart trabecula morphogenesis+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0071773///cellular response to BMP stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090193///positive regulation of glomerulus development+++GO:1905006///negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:2000313///regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation+++GO:2001234///negative regulation of apoptotic signaling pathway 18124 18124 'Nr4a3' mRNA 7 14 3 0.09 0.18 0.03 0.39 0.39 0.49 0.1 0.423333333 40 41 58 8 46.33333333 7.83E-06 2.538247404 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0035035///histone acetyltransferase binding+++GO:0035259///glucocorticoid receptor binding+++GO:0035497///cAMP response element binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001707///mesoderm formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007369///gastrulation+++GO:0007411///axon guidance+++GO:0009444///pyruvate oxidation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0021766///hippocampus development+++GO:0030522///intracellular receptor signaling pathway+++GO:0030534///adult behavior+++GO:0031100///animal organ regeneration+++GO:0032765///positive regulation of mast cell cytokine production+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0038097///positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway+++GO:0042472///inner ear morphogenesis+++GO:0042542///response to hydrogen peroxide+++GO:0043066///negative regulation of apoptotic process+++GO:0043303///mast cell degranulation+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044320///cellular response to leptin stimulus+++GO:0045333///cellular respiration+++GO:0045444///fat cell differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048752///semicircular canal morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050885///neuromuscular process controlling balance+++GO:0060005///vestibular reflex+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0071870///cellular response to catecholamine stimulus+++GO:0097009///energy homeostasis+++GO:1900625///positive regulation of monocyte aggregation+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:2000108///positive regulation of leukocyte apoptotic process+++GO:2000253///positive regulation of feeding behavior" 18125 18125 'Nos1' mRNA 645.38 704 640.11 3.49 3.74 3.67 0.93 1.02 0.99 3.633333333 0.98 197.45 211.59 204.9 663.1633333 204.6466667 6.38E-42 -1.711028159 00220///Arginine biosynthesis+++00330///Arginine and proline metabolism+++04020///Calcium signaling pathway+++04145///Phagosome+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04730///Long-term depression+++04926///Relaxin signaling pathway+++04970///Salivary secretion+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases "GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0012506///vesicle membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030315///T-tubule+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042383///sarcolemma+++GO:0042582///azurophil granule+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0044305///calyx of Held+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component+++GO:0099092///postsynaptic density, intracellular component" GO:0004517///nitric-oxide synthase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008270///zinc ion binding+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0017080///sodium channel regulator activity+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046870///cadmium ion binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0051117///ATPase binding+++GO:0051219///phosphoprotein binding+++GO:0070402///NADPH binding+++GO:0097110///scaffold protein binding "GO:0001666///response to hypoxia+++GO:0002028///regulation of sodium ion transport+++GO:0006527///arginine catabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0006936///muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007263///nitric oxide mediated signal transduction+++GO:0008016///regulation of heart contraction+++GO:0008285///negative regulation of cell proliferation+++GO:0009408///response to heat+++GO:0009725///response to hormone+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0032496///response to lipopolysaccharide+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033555///multicellular organismal response to stress+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0035066///positive regulation of histone acetylation+++GO:0042178///xenobiotic catabolic process+++GO:0042311///vasodilation+++GO:0042738///exogenous drug catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043267///negative regulation of potassium ion transport+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045184///establishment of protein localization+++GO:0045776///negative regulation of blood pressure+++GO:0045822///negative regulation of heart contraction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045906///negative regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0048148///behavioral response to cocaine+++GO:0050767///regulation of neurogenesis+++GO:0051346///negative regulation of hydrolase activity+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051612///negative regulation of serotonin uptake+++GO:0051926///negative regulation of calcium ion transport+++GO:0051930///regulation of sensory perception of pain+++GO:0061875///negative regulation of hepatic stellate cell contraction+++GO:0071260///cellular response to mechanical stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0071872///cellular response to epinephrine stimulus+++GO:0098735///positive regulation of the force of heart contraction+++GO:0098924///retrograde trans-synaptic signaling by nitric oxide+++GO:0099163///synaptic signaling by nitric oxide+++GO:0140196///positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901216///positive regulation of neuron death+++GO:1902307///positive regulation of sodium ion transmembrane transport" 18126 18126 'Nos2' mRNA 329 319 261 4.62 4.44 3.84 1.45 1.49 1.15 4.3 1.363333333 120 120 92 303 110.6666667 2.48E-15 -1.461327067 00220///Arginine biosynthesis+++00330///Arginine and proline metabolism+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04146///Peroxisome+++04371///Apelin signaling pathway+++04926///Relaxin signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05133///Pertussis+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0030863///cortical cytoskeleton+++GO:0048471///perinuclear region of cytoplasm "GO:0003779///actin binding+++GO:0004517///nitric-oxide synthase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008013///beta-catenin binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0019901///protein kinase binding+++GO:0020037///heme binding+++GO:0034617///tetrahydrobiopterin binding+++GO:0034618///arginine binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0050998///nitric-oxide synthase binding+++GO:0051879///Hsp90 protein binding" GO:0001542///ovulation from ovarian follicle+++GO:0001666///response to hypoxia+++GO:0001974///blood vessel remodeling+++GO:0006527///arginine catabolic process+++GO:0006801///superoxide metabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007623///circadian rhythm+++GO:0008016///regulation of heart contraction+++GO:0008217///regulation of blood pressure+++GO:0009617///response to bacterium+++GO:0009725///response to hormone+++GO:0010629///negative regulation of gene expression+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0019934///cGMP-mediated signaling+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0032310///prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034612///response to tumor necrosis factor+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0042127///regulation of cell proliferation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042742///defense response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0045776///negative regulation of blood pressure+++GO:0050796///regulation of insulin secretion+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071407///cellular response to organic cyclic compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1900015///regulation of cytokine production involved in inflammatory response 18127 18127 'Nos3' mRNA 236.33 230.65 244.25 3.09 2.97 3.39 2.72 3.31 2.91 3.15 2.98 239.71 284.89 248.09 237.0766667 257.5633333 0.620646158 0.106921533 00220///Arginine biosynthesis+++00330///Arginine and proline metabolism+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04066///HIF-1 signaling pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04611///Platelet activation+++04915///Estrogen signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0045121///membrane raft+++GO:0045177///apical part of cell "GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0004517///nitric-oxide synthase activity+++GO:0005516///calmodulin binding+++GO:0008013///beta-catenin binding+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0034617///tetrahydrobiopterin binding+++GO:0034618///arginine binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0050998///nitric-oxide synthase binding+++GO:0051879///Hsp90 protein binding+++GO:0097110///scaffold protein binding" GO:0001525///angiogenesis+++GO:0001542///ovulation from ovarian follicle+++GO:0001701///in utero embryonic development+++GO:0001974///blood vessel remodeling+++GO:0002028///regulation of sodium ion transport+++GO:0003057///regulation of the force of heart contraction by chemical signal+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0006527///arginine catabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0007165///signal transduction+++GO:0007263///nitric oxide mediated signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0010628///positive regulation of gene expression+++GO:0014740///negative regulation of muscle hyperplasia+++GO:0014806///smooth muscle hyperplasia+++GO:0019430///removal of superoxide radicals+++GO:0030324///lung development+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0031644///regulation of neurological system process+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0043065///positive regulation of apoptotic process+++GO:0043267///negative regulation of potassium ion transport+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043542///endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051346///negative regulation of hydrolase activity+++GO:0051926///negative regulation of calcium ion transport+++GO:0060412///ventricular septum morphogenesis+++GO:0070168///negative regulation of biomineral tissue development+++GO:0071260///cellular response to mechanical stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0097746///regulation of blood vessel diameter 18128 18128 'Notch1' mRNA 3336 3397 2282 18.42 18.44 13.37 11.83 11.36 11.8 16.74333333 11.66333333 2468 2315 2384 3005 2389 0.001182726 -0.334717193 01522///Endocrine resistance+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++04361///Axon regeneration+++04658///Th1 and Th2 cell differentiation+++04919///Thyroid hormone signaling pathway+++05020///Prion disease+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05224///Breast cancer GO:0000139///Golgi membrane+++GO:0001669///acrosomal vesicle+++GO:0001726///ruffle+++GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0031410///cytoplasmic vesicle+++GO:0043235///receptor complex+++GO:0071944///cell periphery GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004857///enzyme inhibitor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031490///chromatin DNA binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001837///epithelial to mesenchymal transition+++GO:0001889///liver development+++GO:0001947///heart looping+++GO:0002040///sprouting angiogenesis+++GO:0002051///osteoblast fate commitment+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0003151///outflow tract morphogenesis+++GO:0003157///endocardium development+++GO:0003160///endocardium morphogenesis+++GO:0003162///atrioventricular node development+++GO:0003169///coronary vein morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003182///coronary sinus valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003192///mitral valve formation+++GO:0003197///endocardial cushion development+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003203///endocardial cushion morphogenesis+++GO:0003207///cardiac chamber formation+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003209///cardiac atrium morphogenesis+++GO:0003213///cardiac right atrium morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003219///cardiac right ventricle formation+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003241///growth involved in heart morphogenesis+++GO:0003252///negative regulation of cell proliferation involved in heart valve morphogenesis+++GO:0003256///regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0003264///regulation of cardioblast proliferation+++GO:0003270///Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation+++GO:0003273///cell migration involved in endocardial cushion formation+++GO:0003332///negative regulation of extracellular matrix constituent secretion+++GO:0003344///pericardium morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006959///humoral immune response+++GO:0007219///Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007368///determination of left/right symmetry+++GO:0007386///compartment pattern specification+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007440///foregut morphogenesis+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0008593///regulation of Notch signaling pathway+++GO:0009912///auditory receptor cell fate commitment+++GO:0010001///glial cell differentiation+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010832///negative regulation of myotube differentiation+++GO:0014031///mesenchymal cell development+++GO:0014807///regulation of somitogenesis+++GO:0021515///cell differentiation in spinal cord+++GO:0021915///neural tube development+++GO:0030154///cell differentiation+++GO:0030163///protein catabolic process+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030279///negative regulation of ossification+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0031069///hair follicle morphogenesis+++GO:0031100///animal organ regeneration+++GO:0031960///response to corticosteroid+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0032633///interleukin-4 production+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035148///tube formation+++GO:0035914///skeletal muscle cell differentiation+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0042127///regulation of cell proliferation+++GO:0042246///tissue regeneration+++GO:0042640///anagen+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0045070///positive regulation of viral genome replication+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045607///regulation of inner ear auditory receptor cell differentiation+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0045967///negative regulation of growth rate+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048103///somatic stem cell division+++GO:0048663///neuron fate commitment+++GO:0048708///astrocyte differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048845///venous blood vessel morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050434///positive regulation of viral transcription+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0050793///regulation of developmental process+++GO:0051726///regulation of cell cycle+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060038///cardiac muscle cell proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060271///cilium assembly+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060354///negative regulation of cell adhesion molecule production+++GO:0060411///cardiac septum morphogenesis+++GO:0060412///ventricular septum morphogenesis+++GO:0060528///secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development+++GO:0060548///negative regulation of cell death+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060768///regulation of epithelial cell proliferation involved in prostate gland development+++GO:0060842///arterial endothelial cell differentiation+++GO:0060843///venous endothelial cell differentiation+++GO:0060948///cardiac vascular smooth muscle cell development+++GO:0060956///endocardial cell differentiation+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0061314///Notch signaling involved in heart development+++GO:0061344///regulation of cell adhesion involved in heart morphogenesis+++GO:0061384///heart trabecula morphogenesis+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0062043///positive regulation of cardiac epithelial to mesenchymal transition+++GO:0070168///negative regulation of biomineral tissue development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070986///left/right axis specification+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0072017///distal tubule development+++GO:0072044///collecting duct development+++GO:0072144///glomerular mesangial cell development+++GO:0072538///T-helper 17 type immune response+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097150///neuronal stem cell population maintenance+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901189///positive regulation of ephrin receptor signaling pathway+++GO:1901201///regulation of extracellular matrix assembly+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:1902339///positive regulation of apoptotic process involved in morphogenesis+++GO:1903849///positive regulation of aorta morphogenesis+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000737///negative regulation of stem cell differentiation+++GO:2000811///negative regulation of anoikis+++GO:2000974///negative regulation of pro-B cell differentiation+++GO:2001027///negative regulation of endothelial cell chemotaxis" 18129 18129 'Notch2' mRNA 3380 3117 3148 16.83 15.25 16.62 21.38 20.28 21.88 16.23333333 21.18 4946 4586 4904 3215 4812 2.00E-19 0.56921387 01522///Endocrine resistance+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0043235///receptor complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0038023///signaling receptor activity+++GO:0051059///NF-kappaB binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001701///in utero embryonic development+++GO:0001709///cell fate determination+++GO:0001889///liver development+++GO:0001890///placenta development+++GO:0001947///heart looping+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0002315///marginal zone B cell differentiation+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0003184///pulmonary valve morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0007050///cell cycle arrest+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010629///negative regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032633///interleukin-4 production+++GO:0035264///multicellular organism growth+++GO:0035622///intrahepatic bile duct development+++GO:0042060///wound healing+++GO:0042742///defense response to bacterium+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045967///negative regulation of growth rate+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046849///bone remodeling+++GO:0050793///regulation of developmental process+++GO:0051726///regulation of cell cycle+++GO:0060413///atrial septum morphogenesis+++GO:0060674///placenta blood vessel development+++GO:0061073///ciliary body morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070986///left/right axis specification+++GO:0072014///proximal tubule development+++GO:0072015///glomerular visceral epithelial cell development+++GO:0072104///glomerular capillary formation+++GO:0072574///hepatocyte proliferation+++GO:0072576///liver morphogenesis+++GO:1990705///cholangiocyte proliferation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2001204///regulation of osteoclast development" 18130 18130 'Ints6' mRNA 331 298 299 3.59 3.08 3.31 2.95 2.61 3.09 3.326666667 2.883333333 323 273 321 309.3333333 305.6666667 0.876634027 -0.029852472 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton+++GO:0032039///integrator complex GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing 18131 18131 'Notch3' mRNA 352 387 313 2.3 2.48 2.17 1.4 1.46 1.8 2.316666667 1.553333333 247 251 307 350.6666667 268.3333333 0.015224374 -0.394022893 01522///Endocrine resistance+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++04371///Apelin signaling pathway+++04658///Th1 and Th2 cell differentiation+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0045596///negative regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048663///neuron fate commitment+++GO:0048844///artery morphogenesis+++GO:0050793///regulation of developmental process+++GO:0072104///glomerular capillary formation" 18132 18132 'Notch4' mRNA 87 80 32 0.7 0.63 0.27 0.67 0.61 0.79 0.533333333 0.69 96 85 110 66.33333333 97 0.134883887 0.552090524 01522///Endocrine resistance+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001763///morphogenesis of a branching structure+++GO:0001837///epithelial to mesenchymal transition+++GO:0001886///endothelial cell morphogenesis+++GO:0001944///vasculature development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0008593///regulation of Notch signaling pathway+++GO:0030154///cell differentiation+++GO:0030879///mammary gland development+++GO:0032880///regulation of protein localization+++GO:0045446///endothelial cell differentiation+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0048845///venous blood vessel morphogenesis+++GO:0050793///regulation of developmental process+++GO:0060354///negative regulation of cell adhesion molecule production+++GO:0070613///regulation of protein processing+++GO:1903849///positive regulation of aorta morphogenesis+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin" 18133 18133 'Ccn3' mRNA 34 35 33 0.8 0.81 0.82 2.78 2.53 2 0.81 2.436666667 136 121 95 34 117.3333333 3.59E-09 1.77429627 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005921///gap junction+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0005112///Notch binding+++GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding GO:0001525///angiogenesis+++GO:0002062///chondrocyte differentiation+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0010468///regulation of gene expression+++GO:0010761///fibroblast migration+++GO:0010832///negative regulation of myotube differentiation+++GO:0014909///smooth muscle cell migration+++GO:0030308///negative regulation of cell growth+++GO:0033627///cell adhesion mediated by integrin+++GO:0035767///endothelial cell chemotaxis+++GO:0044342///type B pancreatic cell proliferation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0046676///negative regulation of insulin secretion+++GO:0048659///smooth muscle cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0060326///cell chemotaxis+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0060548///negative regulation of cell death+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0071603///endothelial cell-cell adhesion+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1902731///negative regulation of chondrocyte proliferation+++GO:1904057///negative regulation of sensory perception of pain+++GO:1990523///bone regeneration 18139 18139 'Zfp638' mRNA 1480 1484 1415 14.15 13.78 14.37 10.65 11.13 10.41 14.1 10.73 1318 1272 1239 1459.666667 1276.333333 0.011600768 -0.20534404 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008380///RNA splicing 18140 18140 'Uhrf1' mRNA 64 72 57 1.02 1.09 0.95 8.67 8.02 8.68 1.02 8.456666667 640 580 621 64.33333333 613.6666667 4.07E-89 3.24365624 GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0031410///cytoplasmic vesicle GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0016740///transferase activity+++GO:0031493///nucleosomal histone binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0044729///hemi-methylated DNA-binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010216///maintenance of DNA methylation+++GO:0010390///histone monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0050678///regulation of epithelial cell proliferation+++GO:0051865///protein autoubiquitination 18141 18141 'Nup50' mRNA 1001.74 1137.62 1033.28 9.2 10.53 10.43 11.9 12.34 12.39 10.05333333 12.21 1377.09 1393.02 1345.35 1057.546667 1371.82 2.81E-05 0.364811265 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane+++GO:1990904///ribonucleoprotein complex GO:0005515///protein binding GO:0001841///neural tube formation+++GO:0006606///protein import into nucleus+++GO:0051028///mRNA transport 18142 18142 'Npas1' mRNA 8 12 5 0.24 0.36 0.14 0.08 0.11 0.18 0.246666667 0.123333333 3 4 7 8.333333333 4.666666667 0.480184673 -0.831843994 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001964///startle response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042711///maternal behavior+++GO:0045892///negative regulation of transcription, DNA-templated" 18143 18143 'Npas2' mRNA 164 151 113 2.28 2.1 1.59 0.98 0.97 1.18 1.99 1.043333333 79 76 93 142.6666667 82.66666667 0.001497246 -0.79296447 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990513///CLOCK-BMAL transcription complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0051879///Hsp90 protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007623///circadian rhythm+++GO:0009410///response to xenobiotic stimulus+++GO:0032922///circadian regulation of gene expression+++GO:0042493///response to drug+++GO:0042745///circadian sleep/wake cycle+++GO:0042752///regulation of circadian rhythm+++GO:0045475///locomotor rhythm+++GO:0045739///positive regulation of DNA repair+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0051775///response to redox state+++GO:0060548///negative regulation of cell death+++GO:2000987///positive regulation of behavioral fear response+++GO:2001020///regulation of response to DNA damage stimulus" 18145 18145 'Npc1' mRNA 2319 2328 2218.4 23.77 23.47 24.12 24.27 22.68 23.95 23.78666667 23.63333333 2725.99 2486.93 2605.54 2288.466667 2606.153333 0.010805168 0.175047281 04142///Lysosome+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005635///nuclear envelope+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:1905103///integral component of lysosomal membrane GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0015485///cholesterol binding GO:0006486///protein glycosylation+++GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0007041///lysosomal transport+++GO:0007628///adult walking behavior+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008206///bile acid metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010467///gene expression+++GO:0016242///negative regulation of macroautophagy+++GO:0030301///cholesterol transport+++GO:0031579///membrane raft organization+++GO:0032367///intracellular cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0046686///response to cadmium ion+++GO:0046718///viral entry into host cell+++GO:0060548///negative regulation of cell death+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090150///establishment of protein localization to membrane 18146 18146 'Npdc1' mRNA 3000 3090 2808 109.18 112.04 109.36 111.21 117.88 112.43 110.1933333 113.84 3402 3526 3322 2966 3416.666667 0.003096362 0.193867102 GO:0016020///membrane+++GO:0016021///integral component of membrane 18148 18148 'Npm1' mRNA 2508 2489.11 2435 105.99 103.65 108.9 164.94 158.59 169.53 106.18 164.3533333 4477.28 4186.32 4440 2477.37 4367.866667 1.03E-40 0.805712655 GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015934///large ribosomal subunit+++GO:0015935///small ribosomal subunit+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0031616///spindle pole centrosome+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:1990904///ribonucleoprotein complex "GO:0001046///core promoter sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008134///transcription factor binding+++GO:0019843///rRNA binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030957///Tat protein binding+++GO:0033613///activating transcription factor binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043023///ribosomal large subunit binding+++GO:0043024///ribosomal small subunit binding+++GO:0043422///protein kinase B binding+++GO:0047485///protein N-terminus binding+++GO:0051059///NF-kappaB binding+++GO:0051082///unfolded protein binding" "GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000448///cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001558///regulation of cell growth+++GO:0006281///DNA repair+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006407///rRNA export from nucleus+++GO:0006884///cell volume homeostasis+++GO:0006913///nucleocytoplasmic transport+++GO:0007098///centrosome cycle+++GO:0007569///cell aging+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009303///rRNA transcription+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010824///regulation of centrosome duplication+++GO:0010825///positive regulation of centrosome duplication+++GO:0010826///negative regulation of centrosome duplication+++GO:0019827///stem cell population maintenance+++GO:0031328///positive regulation of cellular biosynthetic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032071///regulation of endodeoxyribonuclease activity+++GO:0034644///cellular response to UV+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042274///ribosomal small subunit biogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045727///positive regulation of translation+++GO:0045740///positive regulation of DNA replication+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046599///regulation of centriole replication+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050821///protein stabilization+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0060699///regulation of endoribonuclease activity+++GO:0060735///regulation of eIF2 alpha phosphorylation by dsRNA+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity+++GO:1902629///regulation of mRNA stability involved in cellular response to UV+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:2000381///negative regulation of mesoderm development" 18150 18150 'Npm3' mRNA 38 30 16 2.93 2.29 1.31 1.89 2.56 3.07 2.176666667 2.506666667 28 37 44 28 36.33333333 0.507020307 0.378724063 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0003674///molecular_function+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009303///rRNA transcription+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process 18155 18155 'Pnoc' mRNA 0 4 3 0 0.11 0.09 0.04 0 0.12 0.066666667 0.053333333 1 0 3 2.333333333 1.333333333 0.754495413 -0.826306591 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse GO:0001515///opioid peptide activity+++GO:0031628///opioid receptor binding GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007600///sensory perception 18158 18158 'Nppb' mRNA 0 0 1 0 0 0.05 2.22 2.1 0.93 0.016666667 1.75 24 23 11 0.333333333 19.33333333 8.64E-05 5.740450352 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04714///Thermogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030133///transport vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0051427///hormone receptor binding GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006182///cGMP biosynthetic process+++GO:0006457///protein folding+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0019934///cGMP-mediated signaling+++GO:0030308///negative regulation of cell growth+++GO:0031640///killing of cells of other organism+++GO:0035810///positive regulation of urine volume+++GO:0035815///positive regulation of renal sodium excretion+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1903816///positive regulation of collecting lymphatic vessel constriction+++GO:1904055///negative regulation of cholangiocyte proliferation 18159 18159 'Nppc' mRNA 7 7 10 0.43 0.42 0.64 0.53 0.92 0.66 0.496666667 0.703333333 10 17 12 8 13 0.448939111 0.685531427 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0051427///hormone receptor binding GO:0001503///ossification+++GO:0001666///response to hypoxia+++GO:0003418///growth plate cartilage chondrocyte differentiation+++GO:0003419///growth plate cartilage chondrocyte proliferation+++GO:0006182///cGMP biosynthetic process+++GO:0006457///protein folding+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0022414///reproductive process+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0040014///regulation of multicellular organism growth+++GO:0042493///response to drug+++GO:0043306///positive regulation of mast cell degranulation+++GO:0045471///response to ethanol+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048513///animal organ development+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:1900194///negative regulation of oocyte maturation+++GO:1900721///positive regulation of uterine smooth muscle relaxation+++GO:2000279///negative regulation of DNA biosynthetic process 18160 18160 'Npr1' mRNA 87 89 77 1.15 1.16 1.08 1.72 1.44 2.14 1.13 1.766666667 149 120 177 84.33333333 148.6666667 0.001134575 0.807361569 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04714///Thermogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0016941///natriuretic peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0042562///hormone binding GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0008217///regulation of blood pressure+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0042417///dopamine metabolic process+++GO:0048662///negative regulation of smooth muscle cell proliferation 18162 18162 'Npr3' mRNA 225.94 179.02 154 1.73 1.45 1.26 1.47 1.37 1.44 1.48 1.426666667 216 202 210.05 186.32 209.35 0.47957087 0.162449071 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0008528///G protein-coupled peptide receptor activity+++GO:0016941///natriuretic peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0031404///chloride ion binding+++GO:0042277///peptide binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0001501///skeletal system development+++GO:0002158///osteoclast proliferation+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0008217///regulation of blood pressure+++GO:0030157///pancreatic juice secretion+++GO:0033688///regulation of osteoblast proliferation+++GO:0035810///positive regulation of urine volume+++GO:0042311///vasodilation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0120163///negative regulation of cold-induced thermogenesis 18163 18163 'Ctnnd2' mRNA 884 945 648 8.88 9.22 6.93 1.16 1.82 1.63 8.343333333 1.536666667 128 203 180 825.6666667 170.3333333 1.52E-43 -2.277976536 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon GO:0008013///beta-catenin binding+++GO:0045296///cadherin binding GO:0001763///morphogenesis of a branching structure+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007612///learning+++GO:0048167///regulation of synaptic plasticity+++GO:0050808///synapse organization+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0060997///dendritic spine morphogenesis+++GO:0098609///cell-cell adhesion 18164 18164 'Nptx1' mRNA 864 808 723 8.72 8.01 7.74 3.18 2.74 3.19 8.156666667 3.036666667 363 305 353 798.3333333 340.3333333 1.63E-27 -1.240575539 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043083///synaptic cleft+++GO:0098978///glutamatergic synapse GO:0046872///metal ion binding GO:0006839///mitochondrial transport+++GO:0035865///cellular response to potassium ion+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0060385///axonogenesis involved in innervation+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 18166 18166 'Npy1r' mRNA 228.02 251.42 315.09 3.78 4.24 5.62 3.42 3 3.02 4.546666667 3.146666667 237.52 207.75 202.85 264.8433333 216.04 0.125012383 -0.317539403 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04923///Regulation of lipolysis in adipocytes GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0001601///peptide YY receptor activity+++GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0003151///outflow tract morphogenesis+++GO:0006006///glucose metabolic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007626///locomotory behavior+++GO:0007631///feeding behavior+++GO:0008217///regulation of blood pressure+++GO:0019233///sensory perception of pain+++GO:0030432///peristalsis+++GO:0040014///regulation of multicellular organism growth+++GO:0045907///positive regulation of vasoconstriction+++GO:0046888///negative regulation of hormone secretion+++GO:0051481///negative regulation of cytosolic calcium ion concentration 18167 18167 'Npy2r' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097730///non-motile cilium GO:0001601///peptide YY receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity "GO:0001662///behavioral fear response+++GO:0002793///positive regulation of peptide secretion+++GO:0003151///outflow tract morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007568///aging+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0031645///negative regulation of neurological system process+++GO:0033603///positive regulation of dopamine secretion+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046903///secretion+++GO:0050805///negative regulation of synaptic transmission+++GO:0051048///negative regulation of secretion+++GO:0051930///regulation of sensory perception of pain+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:2000252///negative regulation of feeding behavior" 18169 18169 'Npy6r' mRNA 0 1 0 0 0.02 0 0 0.04 0 0.006666667 0.013333333 0 2 0 0.333333333 0.666666667 0.863090843 0.906692352 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001601///peptide YY receptor activity+++GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 18171 18171 'Nr1i2' mRNA 9 3 7 0.21 0.07 0.17 0.04 0.09 0 0.15 0.043333333 1 4 0 6.333333333 1.666666667 0.20766518 -1.936466446 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0045111///intermediate filament cytoskeleton "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008144///drug binding+++GO:0008270///zinc ion binding+++GO:0016922///nuclear receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006805///xenobiotic metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0042178///xenobiotic catabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0042908///xenobiotic transport+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18173 18173 'Slc11a1' mRNA 118.17 185.93 163.39 2.37 3.59 3.54 36.48 32.24 35.99 3.166666667 34.90333333 1767.9 1561.75 1702.11 155.83 1677.253333 1.59E-164 3.419171483 04142///Lysosome GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0070821///tertiary granule membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0015086///cadmium ion transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0046873///metal ion transmembrane transporter activity+++GO:0046915///transition metal ion transmembrane transporter activity+++GO:0051139///metal ion:proton antiporter activity GO:0000165///MAPK cascade+++GO:0001818///negative regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0002309///T cell proliferation involved in immune response+++GO:0002369///T cell cytokine production+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006828///manganese ion transport+++GO:0006876///cellular cadmium ion homeostasis+++GO:0006879///cellular iron ion homeostasis+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0007035///vacuolar acidification+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0015707///nitrite transport+++GO:0030001///metal ion transport+++GO:0032147///activation of protein kinase activity+++GO:0032496///response to lipopolysaccharide+++GO:0032623///interleukin-2 production+++GO:0032632///interleukin-3 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0034341///response to interferon-gamma+++GO:0034755///iron ion transmembrane transport+++GO:0042060///wound healing+++GO:0042116///macrophage activation+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0045342///MHC class II biosynthetic process+++GO:0045730///respiratory burst+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048002///antigen processing and presentation of peptide antigen+++GO:0048255///mRNA stabilization+++GO:0050766///positive regulation of phagocytosis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0055072///iron ion homeostasis+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0070574///cadmium ion transmembrane transport+++GO:0070839///divalent metal ion export+++GO:0071421///manganese ion transmembrane transport+++GO:1902023///L-arginine transport+++GO:1903826///arginine transmembrane transport 18174 18174 'Slc11a2' mRNA 913 971 930 15.41 15.96 16.72 18.36 17.46 17.11 16.03 17.64333333 1259 1191 1136 938 1195.333333 1.77E-04 0.337281089 04142///Lysosome+++04216///Ferroptosis+++04978///Mineral absorption+++05010///Alzheimer disease+++05012///Parkinson disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005773///vacuole+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031902///late endosome membrane+++GO:0045177///apical part of cell+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0070826///paraferritin complex+++GO:1903561///extracellular vesicle GO:0005375///copper ion transmembrane transporter activity+++GO:0005381///iron ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0005506///iron ion binding+++GO:0005507///copper ion binding+++GO:0008270///zinc ion binding+++GO:0015078///proton transmembrane transporter activity+++GO:0015086///cadmium ion transmembrane transporter activity+++GO:0015087///cobalt ion transmembrane transporter activity+++GO:0015093///ferrous iron transmembrane transporter activity+++GO:0015094///lead ion transmembrane transporter activity+++GO:0015099///nickel cation transmembrane transporter activity+++GO:0015100///vanadium ion transmembrane transporter activity+++GO:0015295///solute:proton symporter activity+++GO:0016151///nickel cation binding+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0030145///manganese ion binding+++GO:0046870///cadmium ion binding+++GO:0046873///metal ion transmembrane transporter activity+++GO:0046915///transition metal ion transmembrane transporter activity+++GO:0050897///cobalt ion binding+++GO:1905394///retromer complex binding GO:0000041///transition metal ion transport+++GO:0001666///response to hypoxia+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0006811///ion transport+++GO:0006824///cobalt ion transport+++GO:0006825///copper ion transport+++GO:0006826///iron ion transport+++GO:0006828///manganese ion transport+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007611///learning or memory+++GO:0010039///response to iron ion+++GO:0010042///response to manganese ion+++GO:0015675///nickel cation transport+++GO:0015676///vanadium ion transport+++GO:0015692///lead ion transport+++GO:0030001///metal ion transport+++GO:0033212///iron assimilation+++GO:0034599///cellular response to oxidative stress+++GO:0034755///iron ion transmembrane transport+++GO:0035444///nickel cation transmembrane transport+++GO:0048813///dendrite morphogenesis+++GO:0048821///erythrocyte development+++GO:0055072///iron ion homeostasis+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0070574///cadmium ion transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0098705///copper ion import across plasma membrane+++GO:1902600///proton transmembrane transport 18175 18175 'Nrap' mRNA 9 12 7 0.09 0.12 0.07 0.15 0.09 0.11 0.093333333 0.116666667 17 10 12 9.333333333 13 0.613085499 0.469467812 GO:0005916///fascia adherens+++GO:0005927///muscle tendon junction+++GO:0030016///myofibril+++GO:0030018///Z disc GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017166///vinculin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051371///muscle alpha-actinin binding GO:0030036///actin cytoskeleton organization+++GO:0048747///muscle fiber development+++GO:0071691///cardiac muscle thin filament assembly 18176 18176 'Nras' mRNA 1300.05 1268.73 1307.7 15.85 15.18 16.94 25.58 26.24 25.27 15.99 25.69666667 2427.77 2417 2321 1292.16 2388.59 1.25E-31 0.873882943 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding GO:0001932///regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042088///T-helper 1 type immune response+++GO:0042832///defense response to protozoan+++GO:0045766///positive regulation of angiogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0050852///T cell receptor signaling pathway+++GO:0051726///regulation of cell cycle 18181 18181 'Nrf1' mRNA 840.59 940.05 850.98 14.23 15.25 14.41 11.92 12.19 13.68 14.63 12.59666667 818.62 786.79 876.1 877.2066667 827.17 0.415204429 -0.095851914 04371///Apelin signaling pathway+++05016///Huntington disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051602///response to electrical stimulus 18183 18183 'Nrg3' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04012///ErbB signaling pathway+++05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0045499///chemorepellent activity GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0021842///chemorepulsion involved in interneuron migration from the subpallium to the cortex+++GO:0030879///mammary gland development+++GO:0035556///intracellular signal transduction+++GO:0048513///animal organ development+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060596///mammary placode formation+++GO:2001223///negative regulation of neuron migration 18186 18186 'Nrp1' mRNA 1315 1273 1172 13.45 13.12 13.01 47.08 47.02 47.88 13.19333333 47.32666667 5207 5033 5163 1253.333333 5134.333333 2.51E-244 2.023862139 04360///Axon guidance+++05166///Human T-cell leukemia virus 1 infection+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005883///neurofilament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097443///sorting endosome+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0017154///semaphorin receptor activity+++GO:0019838///growth factor binding+++GO:0019901///protein kinase binding+++GO:0038085///vascular endothelial growth factor binding+++GO:0046872///metal ion binding "GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001764///neuron migration+++GO:0002040///sprouting angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0007507///heart development+++GO:0008045///motor neuron axon guidance+++GO:0009611///response to wounding+++GO:0009887///animal organ morphogenesis+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0021612///facial nerve structural organization+++GO:0021636///trigeminal nerve morphogenesis+++GO:0021637///trigeminal nerve structural organization+++GO:0021649///vestibulocochlear nerve structural organization+++GO:0021675///nerve development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0030517///negative regulation of axon extension+++GO:0031290///retinal ganglion cell axon guidance+++GO:0031532///actin cytoskeleton reorganization+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035767///endothelial cell chemotaxis+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036486///ventral trunk neural crest cell migration+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0038189///neuropilin signaling pathway+++GO:0038190///VEGF-activated neuropilin signaling pathway+++GO:0042327///positive regulation of phosphorylation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0046718///viral entry into host cell+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048485///sympathetic nervous system development+++GO:0048666///neuron development+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048844///artery morphogenesis+++GO:0048846///axon extension involved in axon guidance+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0050918///positive chemotaxis+++GO:0051491///positive regulation of filopodium assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060385///axonogenesis involved in innervation+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0060980///cell migration involved in coronary vasculogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0061441///renal artery morphogenesis+++GO:0061549///sympathetic ganglion development+++GO:0061551///trigeminal ganglion development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0071679///commissural neuron axon guidance+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090259///regulation of retinal ganglion cell axon guidance+++GO:0097374///sensory neuron axon guidance+++GO:0097475///motor neuron migration+++GO:0097490///sympathetic neuron projection extension+++GO:0097491///sympathetic neuron projection guidance+++GO:0099173///postsynapse organization+++GO:0150018///basal dendrite development+++GO:0150020///basal dendrite arborization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1901998///toxin transport+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1902336///positive regulation of retinal ganglion cell axon guidance+++GO:1902378///VEGF-activated neuropilin signaling pathway involved in axon guidance+++GO:1902946///protein localization to early endosome+++GO:1903375///facioacoustic ganglion development+++GO:1904835///dorsal root ganglion morphogenesis+++GO:1905040///otic placode development+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 18187 18187 'Nrp2' mRNA 2299 2328 2207 23.41 23.3 24.22 19.87 18.09 18.89 23.64333333 18.95 2237.75 1991 2063 2278 2097.25 0.078258972 -0.131801576 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0017154///semaphorin receptor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001755///neural crest cell migration+++GO:0001764///neuron migration+++GO:0003148///outflow tract septum morphogenesis+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007507///heart development+++GO:0021612///facial nerve structural organization+++GO:0021637///trigeminal nerve structural organization+++GO:0021649///vestibulocochlear nerve structural organization+++GO:0021675///nerve development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0036486///ventral trunk neural crest cell migration+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0061549///sympathetic ganglion development+++GO:0061551///trigeminal ganglion development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097374///sensory neuron axon guidance+++GO:0097490///sympathetic neuron projection extension+++GO:0097491///sympathetic neuron projection guidance+++GO:0099175///regulation of postsynapse organization+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1903375///facioacoustic ganglion development+++GO:1904835///dorsal root ganglion morphogenesis+++GO:1990830///cellular response to leukemia inhibitory factor 18188 18188 'Nrtn' mRNA 453 427 38 27.49 25.62 2.48 1.75 4.13 9.14 18.53 5.006666667 33 76 167 306 92 0.169336039 -1.702866397 GO:0005576///extracellular region+++GO:0030424///axon GO:0008083///growth factor activity+++GO:0030116///glial cell-derived neurotrophic factor receptor binding+++GO:0030971///receptor tyrosine kinase binding GO:0001755///neural crest cell migration+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0021675///nerve development+++GO:0031175///neuron projection development 18189 18189 'Nrxn1' mRNA 29 31 21 0.26 0.28 0.15 0.08 0.14 0.05 0.23 0.09 10 20 7 27 12.33333333 0.076707377 -1.130626739 04514///Cell adhesion molecules GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031965///nuclear membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0060077///inhibitory synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0033130///acetylcholine receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0097109///neuroligin family protein binding "GO:0001525///angiogenesis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007158///neuron cell-cell adhesion+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007416///synapse assembly+++GO:0007612///learning+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0021707///cerebellar granule cell differentiation+++GO:0030534///adult behavior+++GO:0031175///neuron projection development+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035176///social behavior+++GO:0035418///protein localization to synapse+++GO:0042297///vocal learning+++GO:0042551///neuron maturation+++GO:0045184///establishment of protein localization+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0046847///filopodium assembly+++GO:0050885///neuromuscular process controlling balance+++GO:0051490///negative regulation of filopodium assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060134///prepulse inhibition+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071277///cellular response to calcium ion+++GO:0071625///vocalization behavior+++GO:0090126///protein-containing complex assembly involved in synapse maturation+++GO:0090129///positive regulation of synapse maturation+++GO:0097091///synaptic vesicle clustering+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:0097114///NMDA glutamate receptor clustering+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly+++GO:0097117///guanylate kinase-associated protein clustering+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0097120///receptor localization to synapse+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0099054///presynapse assembly+++GO:0099150///regulation of postsynaptic specialization assembly+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099542///trans-synaptic signaling by endocannabinoid+++GO:0099560///synaptic membrane adhesion+++GO:1900020///positive regulation of protein kinase C activity+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905606///regulation of presynapse assembly+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000821///regulation of grooming behavior" 18190 18190 'Nrxn2' mRNA 76 80 50 0.62 0.63 0.43 0.14 0.13 0.17 0.56 0.146666667 20 18 22 68.66666667 20 6.21E-06 -1.783080954 04514///Cell adhesion molecules GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0097109///neuroligin family protein binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007416///synapse assembly+++GO:0030534///adult behavior+++GO:0035176///social behavior+++GO:0042297///vocal learning+++GO:0071625///vocalization behavior+++GO:0097104///postsynaptic membrane assembly+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0097119///postsynaptic density protein 95 clustering 18191 18191 'Nrxn3' mRNA 3514 3604 3264 22.99 23.14 22.59 1.68 1.48 1.53 22.90666667 1.563333333 297 254 265 3460.666667 272 0 -3.68066403 04514///Cell adhesion molecules GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0098982///GABA-ergic synapse GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007416///synapse assembly+++GO:0007612///learning+++GO:0030534///adult behavior+++GO:0035176///social behavior+++GO:0071625///vocalization behavior+++GO:2000300///regulation of synaptic vesicle exocytosis 18193 18193 'Nsd1' mRNA 2693 2658 2340 11 10.67 10.19 8.72 7.86 8.29 10.62 8.29 2442 2153 2253 2563.666667 2282.666667 0.013855399 -0.178020876 00310///Lysine degradation GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035097///histone methyltransferase complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0030331///estrogen receptor binding+++GO:0042054///histone methyltransferase activity+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0042974///retinoic acid receptor binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific)+++GO:0050681///androgen receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000414///regulation of histone H3-K36 methylation+++GO:0001702///gastrulation with mouth forming second+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0010452///histone H3-K36 methylation+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0034770///histone H4-K20 methylation+++GO:0034968///histone lysine methylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding" 18194 18194 'Nsdhl' mRNA 1262 1337 1309 32.05 33.44 35.27 16.89 17.82 17.68 33.58666667 17.46333333 765 788 775 1302.666667 776 1.45E-17 -0.759542621 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000252///C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0047012///sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity+++GO:0102175///3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity+++GO:0103066///4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity+++GO:0103067///4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity" GO:0001942///hair follicle development+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0007224///smoothened signaling pathway+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0060716///labyrinthine layer blood vessel development 18195 18195 'Nsf' mRNA 1626 1719 1803 23.38 24.32 27.5 24.88 25.81 23.7 25.06666667 24.79666667 1991 2018 1837 1716 1948.666667 0.071014306 0.169252034 04721///Synaptic vesicle cycle+++04727///GABAergic synapse+++04962///Vasopressin-regulated water reabsorption GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0043198///dendritic shaft+++GO:0043209///myelin sheath GO:0000149///SNARE binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017075///syntaxin-1 binding+++GO:0019901///protein kinase binding+++GO:0019905///syntaxin binding+++GO:0030165///PDZ domain binding+++GO:0031267///small GTPase binding+++GO:0031748///D1 dopamine receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0043008///ATP-dependent protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001921///positive regulation of receptor recycling+++GO:0002090///regulation of receptor internalization+++GO:0006813///potassium ion transport+++GO:0006886///intracellular protein transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0017157///regulation of exocytosis+++GO:0032984///protein-containing complex disassembly+++GO:0035494///SNARE complex disassembly+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0048211///Golgi vesicle docking 18196 18196 'Nsg1' mRNA 1240.44 1296.26 1276.61 28.61 29.42 31.16 26.31 27.26 26.46 29.73 26.67666667 1309.82 1326.47 1276.26 1271.103333 1304.183333 0.841185907 0.024662628 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032580///Golgi cisterna membrane+++GO:0032585///multivesicular body membrane+++GO:0032588///trans-Golgi network membrane+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0043202///lysosomal lumen+++GO:0045211///postsynaptic membrane+++GO:0055038///recycling endosome membrane+++GO:0098845///postsynaptic endosome+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0032051///clathrin light chain binding "GO:0001881///receptor recycling+++GO:0001921///positive regulation of receptor recycling+++GO:0006915///apoptotic process+++GO:0007212///dopamine receptor signaling pathway+++GO:0016197///endosomal transport+++GO:0042982///amyloid precursor protein metabolic process+++GO:0048268///clathrin coat assembly+++GO:0098814///spontaneous synaptic transmission+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0099627///neurotransmitter receptor cycle+++GO:0099630///postsynaptic neurotransmitter receptor cycle+++GO:1900271///regulation of long-term synaptic potentiation" 18197 18197 'Nsg2' mRNA 488 518 327 11.98 12.67 8.7 0.92 0.99 1.73 11.11666667 1.213333333 41 44 76 444.3333333 53.66666667 3.68E-41 -3.050778538 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032580///Golgi cisterna membrane+++GO:0032585///multivesicular body membrane+++GO:0032588///trans-Golgi network membrane+++GO:0042995///cell projection+++GO:0043202///lysosomal lumen+++GO:1990674///Golgi cis cisterna membrane GO:0032051///clathrin light chain binding GO:0007212///dopamine receptor signaling pathway+++GO:0016197///endosomal transport+++GO:0048268///clathrin coat assembly 18198 18198 'Musk' mRNA 392 375 322 4.98 4.91 3.86 6.4 6.57 6.43 4.583333333 6.466666667 479 474 424 363 459 0.016052792 0.329364234 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0038062///protein tyrosine kinase collagen receptor activity+++GO:0046872///metal ion binding "GO:0001934///positive regulation of protein phosphorylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007528///neuromuscular junction development+++GO:0007613///memory+++GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0033674///positive regulation of kinase activity+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0043113///receptor clustering+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045887///positive regulation of synaptic growth at neuromuscular junction+++GO:0046777///protein autophosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051602///response to electrical stimulus+++GO:0060291///long-term synaptic potentiation+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:2000541///positive regulation of protein geranylgeranylation" 18201 18201 'Nsmaf' mRNA 676 684 394 10.87 10.98 6.77 6.86 5.58 6.44 9.54 6.293333333 449 386 448 584.6666667 427.6666667 0.008230977 -0.45267354 04071///Sphingolipid signaling pathway GO:0005123///death receptor binding+++GO:0016230///sphingomyelin phosphodiesterase activator activity GO:0043065///positive regulation of apoptotic process+++GO:0050790///regulation of catalytic activity 18203 18203 'Ntan1' mRNA 1068 1061.13 1104.16 61.98 60.1 67.54 52.54 57.52 55.05 63.20666667 55.03666667 1074.59 1159 1083.23 1077.763333 1105.606667 0.863090843 0.023928707 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0016787///hydrolase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007613///memory+++GO:0008344///adult locomotory behavior 18205 18205 'Ntf3' mRNA 39 52 55 1.69 2.2 2.62 0.58 0.89 0.77 2.17 0.746666667 15 22 19 48.66666667 18.66666667 0.002073473 -1.395978554 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04722///Neurotrophin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0008021///synaptic vesicle+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle GO:0005102///signaling receptor binding+++GO:0005163///nerve growth factor receptor binding+++GO:0005165///neurotrophin receptor binding+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity+++GO:0048406///nerve growth factor binding GO:0000187///activation of MAPK activity+++GO:0002092///positive regulation of receptor internalization+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007274///neuromuscular synaptic transmission+++GO:0007399///nervous system development+++GO:0007403///glial cell fate determination+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007422///peripheral nervous system development+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0021675///nerve development+++GO:0030335///positive regulation of cell migration+++GO:0032148///activation of protein kinase B activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038180///nerve growth factor signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0042552///myelination+++GO:0042981///regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048484///enteric nervous system development+++GO:0048666///neuron development+++GO:0048699///generation of neurons+++GO:0048812///neuron projection morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050930///induction of positive chemotaxis+++GO:0051145///smooth muscle cell differentiation+++GO:0090630///activation of GTPase activity+++GO:2000251///positive regulation of actin cytoskeleton reorganization 18207 18207 'Nthl1' mRNA 232 278 263 12.51 14.51 14.31 11.08 10.96 11.13 13.77666667 11.05666667 240 230 225 257.6666667 231.6666667 0.394073828 -0.16630049 03410///Base excision repair GO:0005634///nucleus+++GO:0005739///mitochondrion "GO:0000703///oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016829///lyase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity" "GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006285///base-excision repair, AP site formation+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 18208 18208 'Ntn1' mRNA 939 953 755 8.7 8.68 7.42 1.62 1.45 1.37 8.266666667 1.48 202 176 165 882.3333333 181 3.06E-73 -2.29375801 04360///Axon guidance+++04361///Axon regeneration GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071944///cell periphery GO:0005125///cytokine activity+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding "GO:0001764///neuron migration+++GO:0002456///T cell mediated immunity+++GO:0006915///apoptotic process+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007097///nuclear migration+++GO:0007265///Ras protein signal transduction+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016358///dendrite development+++GO:0019724///B cell mediated immunity+++GO:0030334///regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0030879///mammary gland development+++GO:0032488///Cdc42 protein signal transduction+++GO:0033564///anterior/posterior axon guidance+++GO:0042100///B cell proliferation+++GO:0042472///inner ear morphogenesis+++GO:0045773///positive regulation of axon extension+++GO:0051963///regulation of synapse assembly+++GO:0060603///mammary gland duct morphogenesis+++GO:0061643///chemorepulsion of axon+++GO:0098609///cell-cell adhesion+++GO:2000147///positive regulation of cell motility" 18209 18209 'Ntn3' mRNA 210 177 69 2.29 1.89 0.8 0.88 1.05 1.34 1.66 1.09 93 108 137 152 112.6666667 0.243376231 -0.423129567 04360///Axon guidance GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005794///Golgi apparatus GO:0005102///signaling receptor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007409///axonogenesis+++GO:0007520///myoblast fusion+++GO:0008045///motor neuron axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016358///dendrite development" 18211 18211 'Ntrk1' mRNA 5 0 1 0.12 0 0.02 0.05 0.03 0 0.046666667 0.026666667 2 1 0 2 1 0.734053465 -1.012818318 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04722///Neurotrophin signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05216///Thyroid cancer+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005030///neurotrophin receptor activity+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0010465///nerve growth factor receptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043121///neurotrophin binding+++GO:0048406///nerve growth factor binding "GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007568///aging+++GO:0007611///learning or memory+++GO:0007623///circadian rhythm+++GO:0008285///negative regulation of cell proliferation+++GO:0009314///response to radiation+++GO:0009410///response to xenobiotic stimulus+++GO:0010623///programmed cell death involved in cell development+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019233///sensory perception of pain+++GO:0021553///olfactory nerve development+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0031175///neuron projection development+++GO:0031667///response to nutrient levels+++GO:0033674///positive regulation of kinase activity+++GO:0035094///response to nicotine+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0038180///nerve growth factor signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0042493///response to drug+++GO:0043068///positive regulation of programmed cell death+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046777///protein autophosphorylation+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048013///ephrin receptor signaling pathway+++GO:0048485///sympathetic nervous system development+++GO:0048666///neuron development+++GO:0048678///response to axon injury+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051599///response to hydrostatic pressure+++GO:0051602///response to electrical stimulus+++GO:0051896///regulation of protein kinase B signaling+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060009///Sertoli cell development+++GO:0060384///innervation+++GO:0060385///axonogenesis involved in innervation+++GO:0061368///behavioral response to formalin induced pain+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071316///cellular response to nicotine+++GO:0071363///cellular response to growth factor stimulus+++GO:1901215///negative regulation of neuron death+++GO:1990090///cellular response to nerve growth factor stimulus" 18212 18212 'Ntrk2' mRNA 1673 1667 1516 11.83 11.56 11.38 9.69 8.86 9.98 11.59 9.51 1550 1401 1552 1618.666667 1501 0.158589695 -0.119837583 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04722///Neurotrophin signaling pathway+++05034///Alcoholism GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043235///receptor complex+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005030///neurotrophin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0042803///protein homodimerization activity+++GO:0043121///neurotrophin binding+++GO:0048403///brain-derived neurotrophic factor binding+++GO:0060175///brain-derived neurotrophic factor-activated receptor activity "GO:0001570///vasculogenesis+++GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007528///neuromuscular junction development+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0007623///circadian rhythm+++GO:0007631///feeding behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014047///glutamate secretion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019222///regulation of metabolic process+++GO:0019227///neuronal action potential propagation+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0022011///myelination in peripheral nervous system+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0038179///neurotrophin signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0043087///regulation of GTPase activity+++GO:0043408///regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046548///retinal rod cell development+++GO:0046777///protein autophosphorylation+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048709///oligodendrocyte differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0050772///positive regulation of axonogenesis+++GO:0050773///regulation of dendrite development+++GO:0051896///regulation of protein kinase B signaling+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060041///retina development in camera-type eye+++GO:0060291///long-term synaptic potentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071230///cellular response to amino acid stimulus+++GO:0099183///trans-synaptic signaling by BDNF, modulating synaptic transmission+++GO:0099551///trans-synaptic signaling by neuropeptide, modulating synaptic transmission+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway+++GO:2000811///negative regulation of anoikis" 18213 18213 'Ntrk3' mRNA 530.7 576.05 477.78 6.27 6.06 5.7 4.4 4.77 3.79 6.01 4.32 418.18 421.4 364.09 528.1766667 401.2233333 0.00161049 -0.405146852 04020///Calcium signaling pathway+++04722///Neurotrophin signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043235///receptor complex+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0005030///neurotrophin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043121///neurotrophin binding GO:0000187///activation of MAPK activity+++GO:0001764///neuron migration+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019056///modulation by virus of host transcription+++GO:0019227///neuronal action potential propagation+++GO:0022011///myelination in peripheral nervous system+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0032148///activation of protein kinase B activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0038179///neurotrophin signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045471///response to ethanol+++GO:0048013///ephrin receptor signaling pathway+++GO:0048665///neuron fate specification+++GO:0048678///response to axon injury+++GO:0048691///positive regulation of axon extension involved in regeneration+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0050927///positive regulation of positive chemotaxis+++GO:0051412///response to corticosterone+++GO:0051896///regulation of protein kinase B signaling+++GO:0051965///positive regulation of synapse assembly+++GO:0060548///negative regulation of cell death+++GO:0070306///lens fiber cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0090102///cochlea development+++GO:0090630///activation of GTPase activity+++GO:0099151///regulation of postsynaptic density assembly+++GO:1905606///regulation of presynapse assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000251///positive regulation of actin cytoskeleton reorganization 18214 18214 'Ddr2' mRNA 1456 1556 1389 9.08 9.52 9.07 12.22 12.91 12.21 9.223333333 12.44666667 2273 2374 2203 1467 2283.333333 8.09E-18 0.62821714 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005518///collagen binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0038062///protein tyrosine kinase collagen receptor activity GO:0001503///ossification+++GO:0003416///endochondral bone growth+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0010763///positive regulation of fibroblast migration+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030199///collagen fibril organization+++GO:0030500///regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0033674///positive regulation of kinase activity+++GO:0034103///regulation of tissue remodeling+++GO:0035988///chondrocyte proliferation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046777///protein autophosphorylation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0090091///positive regulation of extracellular matrix disassembly 18216 18216 'Ntsr1' mRNA 0 2 0 0 0.03 0 0.02 0 0.02 0.01 0.013333333 2 0 2 0.666666667 1.333333333 0.784738507 1.013263733 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032280///symmetric synapse+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0044309///neuron spine+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0016492///G protein-coupled neurotensin receptor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0001659///temperature homeostasis+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003254///regulation of membrane depolarization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007612///learning+++GO:0008344///adult locomotory behavior+++GO:0014049///positive regulation of glutamate secretion+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0033993///response to lipid+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051930///regulation of sensory perception of pain+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0070779///D-aspartate import across plasma membrane+++GO:0071545///inositol phosphate catabolic process+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0098712///L-glutamate import across plasma membrane+++GO:0098900///regulation of action potential+++GO:2001259///positive regulation of cation channel activity 18217 18217 'Ntsr2' mRNA 18 19 13 0.74 0.79 0.52 0.73 0.5 0.54 0.683333333 0.59 21 14 15 16.66666667 16.66666667 0.998257897 -0.008866889 04080///Neuroactive ligand-receptor interaction GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon GO:0004930///G protein-coupled receptor activity+++GO:0016492///G protein-coupled neurotensin receptor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0042391///regulation of membrane potential+++GO:0043410///positive regulation of MAPK cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 18218 18218 'Dusp8' mRNA 338.86 289.82 305.77 3.82 3.22 3.67 3.69 3.72 3.87 3.57 3.76 375.96 369.99 385 311.4833333 376.9833333 0.083244461 0.264504055 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade 18220 18220 'Nucb1' mRNA 4341 4570 4702 98.83 102.62 113.74 155.94 148.25 147.99 105.0633333 150.7266667 7862 7323 7243 4537.666667 7476 7.63E-27 0.705752609 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0090498///extrinsic component of Golgi membrane+++GO:0098547///lumenal side of Golgi membrane GO:0001965///G-protein alpha-subunit binding+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0072718///response to cisplatin+++GO:1903533///regulation of protein targeting 18221 18221 'Nudc' mRNA 3785 3895 3626 168.95 171.58 171.72 127.39 135.25 131.83 170.75 131.49 3277 3394 3280 3768.666667 3317 0.002148407 -0.194907525 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007080///mitotic metaphase plate congression+++GO:0007097///nuclear migration+++GO:0051301///cell division 18222 18222 'Numb' mRNA 1215.63 1170.35 1190.04 18.04 17.22 18.8 14.65 14.69 13.85 18.02 14.39666667 1122.1 1097.17 1021.71 1192.006667 1080.326667 0.109173119 -0.154758528 04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043197///dendritic spine+++GO:0045177///apical part of cell+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007405///neuroblast proliferation+++GO:0007409///axonogenesis+++GO:0021670///lateral ventricle development+++GO:0021849///neuroblast division in subventricular zone+++GO:0030335///positive regulation of cell migration+++GO:0030862///positive regulation of polarized epithelial cell differentiation+++GO:0030900///forebrain development+++GO:0034332///adherens junction organization+++GO:0045664///regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0050769///positive regulation of neurogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0060487///lung epithelial cell differentiation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0099150///regulation of postsynaptic specialization assembly+++GO:1903077///negative regulation of protein localization to plasma membrane 18223 18223 'Numbl' mRNA 174 175 117 3.6 3.25 2.56 2.87 3.3 3.34 3.136666667 3.17 165 182 183 155.3333333 176.6666667 0.469672384 0.182119164 04330///Notch signaling pathway GO:0005737///cytoplasm GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007405///neuroblast proliferation+++GO:0007409///axonogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019538///protein metabolic process+++GO:0021670///lateral ventricle development+++GO:0021849///neuroblast division in subventricular zone+++GO:0030900///forebrain development+++GO:0034332///adherens junction organization+++GO:0050769///positive regulation of neurogenesis+++GO:0050775///positive regulation of dendrite morphogenesis 18226 18226 'Nup62' mRNA 633 612 612 9.15 8.71 9.39 13.63 13.72 15.04 9.083333333 14.13 1085 1067 1159 619 1103.666667 4.05E-18 0.822392481 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005642///annulate lamellae+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0044613///nuclear pore central transport channel+++GO:0072686///mitotic spindle+++GO:0090543///Flemming body+++GO:1990904///ribonucleoprotein complex GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0017056///structural constituent of nuclear pore+++GO:0019894///kinesin binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030544///Hsp70 protein binding+++GO:0042169///SH2 domain binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0051425///PTB domain binding+++GO:0051879///Hsp90 protein binding "GO:0000278///mitotic cell cycle+++GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0007080///mitotic metaphase plate congression+++GO:0007098///centrosome cycle+++GO:0007100///mitotic centrosome separation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007569///cell aging+++GO:0008219///cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0015031///protein transport+++GO:0016477///cell migration+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042306///regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046601///positive regulation of centriole replication+++GO:0051028///mRNA transport+++GO:0051169///nuclear transport+++GO:0060236///regulation of mitotic spindle organization+++GO:0098534///centriole assembly+++GO:1903438///positive regulation of mitotic cytokinetic process+++GO:1904781///positive regulation of protein localization to centrosome" 18227 18227 'Nr4a2' mRNA 321 295 246 5.27 4.8 4.32 2.85 2.12 2.33 4.796666667 2.433333333 198 143 160 287.3333333 167 1.21E-05 -0.793278211 "04925///Aldosterone synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001764///neuron migration+++GO:0001975///response to amphetamine+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007611///learning or memory+++GO:0008344///adult locomotory behavior+++GO:0009791///post-embryonic development+++GO:0010035///response to inorganic substance+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0017085///response to insecticide+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0021953///central nervous system neuron differentiation+++GO:0021986///habenula development+++GO:0030182///neuron differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0034599///cellular response to oxidative stress+++GO:0042053///regulation of dopamine metabolic process+++GO:0042416///dopamine biosynthetic process+++GO:0042417///dopamine metabolic process+++GO:0042551///neuron maturation+++GO:0043085///positive regulation of catalytic activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051866///general adaptation syndrome+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0071542///dopaminergic neuron differentiation+++GO:2001234///negative regulation of apoptotic signaling pathway" 18230 18230 'Nxn' mRNA 375 423 364 7.6 8.44 7.83 6.61 5.56 6.66 7.956666667 6.276666667 375 308 366 387.3333333 349.6666667 0.323856691 -0.158972584 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004791///thioredoxin-disulfide reductase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0047134///protein-disulfide reductase activity GO:0001701///in utero embryonic development+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031397///negative regulation of protein ubiquitination+++GO:0072359///circulatory system development+++GO:0098869///cellular oxidant detoxification 18231 18231 'Nxph1' mRNA 0 4 1 0 0.06 0 0 0 0.03 0.02 0.01 0 0 2 1.666666667 0.666666667 0.704909614 -1.30798949 GO:0005576///extracellular region GO:0005102///signaling receptor binding 18241 18241 'Gpr143' mRNA 30 32 63 1.06 1.11 2.36 1.9 1.76 1.75 1.51 1.803333333 57 56 55 41.66666667 56 0.398604079 0.398112656 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome GO:0004930///G protein-coupled receptor activity+++GO:0035240///dopamine binding+++GO:0035643///L-DOPA receptor activity+++GO:0072544///L-DOPA binding+++GO:0072545///tyrosine binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0032400///melanosome localization+++GO:0032402///melanosome transport+++GO:0032438///melanosome organization+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050848///regulation of calcium-mediated signaling+++GO:1902908///regulation of melanosome transport+++GO:1903056///regulation of melanosome organization 18242 18242 'Oat' mRNA 8037 8482 8163 210.68 218.99 227 247.89 239.45 241.4 218.89 242.9133333 10874 10255 10250 8227.333333 10459.66667 8.94E-10 0.333607273 00330///Arginine and proline metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003824///catalytic activity+++GO:0004587///ornithine-oxo-acid transaminase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding+++GO:0050155///ornithine(lysine) transaminase activity GO:0010121///arginine catabolic process to proline via ornithine+++GO:0019544///arginine catabolic process to glutamate+++GO:0055129///L-proline biosynthetic process 18245 18245 'Oaz1' mRNA 14451 15577 14866 845.07 900.27 922.37 942.71 989.12 933.28 889.2366667 955.0366667 18491 18915 17695 14964.66667 18367 1.10E-06 0.283544641 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008073///ornithine decarboxylase inhibitor activity+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0043086///negative regulation of catalytic activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0090316///positive regulation of intracellular protein transport+++GO:1902268///negative regulation of polyamine transmembrane transport 18247 18247 'Oaz2' mRNA 9085 9574 8914 283.15 294.05 294.74 233.54 246.03 231.09 290.6466667 236.8866667 8613 8857 8248 9191 8572.666667 0.068258329 -0.111577791 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008073///ornithine decarboxylase inhibitor activity GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0043086///negative regulation of catalytic activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0090316///positive regulation of intracellular protein transport+++GO:1902268///negative regulation of polyamine transmembrane transport 18256 18256 'Oc90' mRNA 373 321 389 11.71 10.01 13.14 1.3 1.36 1.37 11.62 1.343333333 42 47 49 361 46 5.44E-46 -2.987501619 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004623///phospholipase A2 activity+++GO:0005198///structural molecule activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006644///phospholipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0045299///otolith mineralization+++GO:0050482///arachidonic acid secretion 18260 18260 'Ocln' mRNA 1601 1706 1723 24.85 26.51 29.11 21.65 21.39 20.86 26.82333333 21.3 1565 1528 1477 1676.666667 1523.333333 0.090079892 -0.151893894 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0070160///tight junction GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0001933///negative regulation of protein phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010827///regulation of glucose transmembrane transport+++GO:0045216///cell-cell junction organization+++GO:0046326///positive regulation of glucose import+++GO:0070673///response to interleukin-18+++GO:0070830///bicellular tight junction assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0120193///tight junction organization+++GO:1905605///positive regulation of maintenance of permeability of blood-brain barrier 18261 18261 'Ocm' mRNA 1816 1709 1695 168.76 158.2 167.53 12.84 13.78 12.44 164.83 13.02 158 164 147 1740 156.3333333 6.01E-230 -3.488268696 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031982///vesicle+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0032991///protein-containing complex+++GO:0099512///supramolecular fiber GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0009611///response to wounding+++GO:0048691///positive regulation of axon extension involved in regeneration+++GO:0090102///cochlea development+++GO:1902336///positive regulation of retinal ganglion cell axon guidance+++GO:1905593///positive regulation of optical nerve axon regeneration 18263 18263 'Odc1' mRNA 2211 2161 1205 48.26 46.44 27.9 21.58 19.59 22.34 40.86666667 21.17 1138 1008 1140 1859 1095.333333 0.003694329 -0.762642981 00330///Arginine and proline metabolism+++00480///Glutathione metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0003824///catalytic activity+++GO:0004586///ornithine decarboxylase activity+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0042803///protein homodimerization activity GO:0001822///kidney development+++GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009446///putrescine biosynthetic process+++GO:0033387///putrescine biosynthetic process from ornithine+++GO:0042176///regulation of protein catabolic process 18285 18285 'Odf1' mRNA 1 0 1 0.06 0 0.06 0 0 0 0.04 0 0 0 0 0.666666667 0 0.746936975 -1.892661915 GO:0001520///outer dense fiber GO:0019904///protein domain specific binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 18286 18286 'Odf2' mRNA 1079 1034 1079 15.98 15.04 16.75 11.51 11.52 11.97 15.92333333 11.66666667 897 867 916 1064 893.3333333 0.006038592 -0.265413465 GO:0000922///spindle pole+++GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097539///ciliary transition fiber+++GO:0120103///centriolar subdistal appendage GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008104///protein localization+++GO:0010457///centriole-centriole cohesion+++GO:0030154///cell differentiation+++GO:0044782///cilium organization+++GO:1902017///regulation of cilium assembly 18291 18291 'Nobox' mRNA 4 12 10 0.12 0.35 0.3 0 0.05 0 0.256666667 0.016666667 0 2 0 8.666666667 0.666666667 0.021485406 -3.706846229 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" GO:0001541///ovarian follicle development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis 18293 18293 'Ogdh' mRNA 5956.35 6080.52 6139.82 69.46 70.49 75.49 71.57 69.82 69.46 71.81333333 70.28333333 7130.31 6685.68 6688.16 6058.896667 6834.716667 0.011865042 0.160181013 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0031966///mitochondrial membrane+++GO:0045252///oxoglutarate dehydrogenase complex "GO:0004591///oxoglutarate dehydrogenase (succinyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0030976///thiamine pyrophosphate binding+++GO:0031072///heat shock protein binding+++GO:0034602///oxoglutarate dehydrogenase (NAD+) activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding" GO:0006091///generation of precursor metabolites and energy+++GO:0006096///glycolytic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0006734///NADH metabolic process+++GO:0021695///cerebellar cortex development+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021794///thalamus development+++GO:0021860///pyramidal neuron development+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0061034///olfactory bulb mitral cell layer development+++GO:0106077///histone succinylation 18294 18294 'Ogg1' mRNA 146.16 136.36 126.02 4.9 4.44 4.48 4.72 4.38 4.06 4.606666667 4.386666667 160.01 147.12 140.62 136.18 149.25 0.652534402 0.120694026 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex "GO:0000702///oxidized base lesion DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003824///catalytic activity+++GO:0008017///microtubule binding+++GO:0008534///oxidized purine nucleobase lesion DNA N-glycosylase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016829///lyase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0032357///oxidized purine DNA binding+++GO:0034039///8-oxo-7,8-dihydroguanine DNA N-glycosylase activity+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity" "GO:0002526///acute inflammatory response+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006285///base-excision repair, AP site formation+++GO:0006289///nucleotide-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0008152///metabolic process+++GO:0009314///response to radiation+++GO:0009416///response to light stimulus+++GO:0032355///response to estradiol+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0051593///response to folic acid+++GO:0071276///cellular response to cadmium ion+++GO:1901291///negative regulation of double-strand break repair via single-strand annealing" 18295 18295 'Ogn' mRNA 1766 1724 1764 37.77 36.29 40.02 50.47 47.25 49.81 38.02666667 49.17666667 2715 2482 2594 1751.333333 2597 7.42E-15 0.554891814 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0008083///growth factor activity+++GO:0030021///extracellular matrix structural constituent conferring compression resistance GO:0007165///signal transduction+++GO:0048662///negative regulation of smooth muscle cell proliferation 18300 18300 'Oit1' mRNA 71 46 41 3.47 2.15 2.09 1.46 1.89 2 2.57 1.783333333 29 38 43 52.66666667 36.66666667 0.233372384 -0.526552949 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0046676///negative regulation of insulin secretion+++GO:0070093///negative regulation of glucagon secretion 18301 18301 'Fxyd5' mRNA 543 534 471 33.21 32.54 30.71 301.9 329.94 297.26 32.15333333 309.7 5676 6053 5405 516 5711.333333 0 3.459167824 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003779///actin binding+++GO:0017080///sodium channel regulator activity+++GO:0045296///cadherin binding+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0043269///regulation of ion transport+++GO:2000649///regulation of sodium ion transmembrane transporter activity 18302 18302 'Oit3' mRNA 0 0 1 0 0 0.02 0.37 0.4 0.6 0.006666667 0.456666667 21 22 33 0.333333333 25.33333333 1.18E-05 6.133611707 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0009986///cell surface GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:1903118///urate homeostasis 18312 18312 'Olfr15' mRNA 0 0 2 0 0 0.15 0 0 0 0.05 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050907///detection of chemical stimulus involved in sensory perception+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18313 18313 'Olfr16' mRNA 6 11 4 0.36 0.65 0.26 0 0 0.22 0.423333333 0.073333333 0 0 4 7 1.333333333 0.133321899 -2.38320536 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007268///chemical synaptic transmission+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 18315 18315 'Olfr18' mRNA 0 1 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18323 18323 'Olfr25' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18346 18346 'Olfr47' mRNA 1 1 0 0.07 0.07 0 0 0 0 0.046666667 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032154///cleavage furrow+++GO:0055037///recycling endosome+++GO:0090543///Flemming body+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18348 18348 'Olfr49' mRNA 0 1 0 0 0.06 0 0 0 0.11 0.02 0.036666667 0 0 2 0.333333333 0.666666667 0.863090843 0.890650273 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0019840///isoprenoid binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18356 18356 'Olfr56' mRNA 0 0 1 0 0 0.05 0 0.05 0 0.016666667 0.016666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18357 18357 'Olfr57' mRNA 6 3 7 0.35 0.17 0.43 0.1 0.05 0.1 0.316666667 0.083333333 2 1 2 5.333333333 1.666666667 0.261372048 -1.705326184 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18361 18361 'Olfr60' mRNA 0 1 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 18377 18377 'Omg' mRNA 55 68 59 1.39 1.69 1.58 1.01 0.79 0.84 1.553333333 0.88 46 35 37 60.66666667 39.33333333 0.088955992 -0.638117394 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043209///myelin sheath GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0007155///cell adhesion+++GO:0022010///central nervous system myelination+++GO:0031102///neuron projection regeneration+++GO:0048683///regulation of collateral sprouting of intact axon in response to injury 18378 18378 'Omp' mRNA 15 14 11 0.41 0.37 0.32 0.52 0.15 0.34 0.366666667 0.336666667 22 6 14 13.33333333 14 0.955909453 0.054375697 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007608///sensory perception of smell+++GO:0022008///neurogenesis+++GO:0050896///response to stimulus 18383 18383 'Tnfrsf11b' mRNA 1623 1687 1718 31.78 32.51 35.69 122.56 123.56 119.14 33.32666667 121.7533333 7201 7090 6778 1676 7023 1.24E-218 2.05378631 04060///Cytokine-cytokine receptor interaction+++04380///Osteoclast differentiation GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007584///response to nutrient+++GO:0010035///response to inorganic substance+++GO:0030198///extracellular matrix organization+++GO:0032026///response to magnesium ion+++GO:0042489///negative regulation of odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0043627///response to estrogen+++GO:0045779///negative regulation of bone resorption+++GO:0046685///response to arsenic-containing substance 18386 18386 'Oprd1' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031982///vesicle+++GO:0032590///dendrite membrane+++GO:0043005///neuron projection+++GO:0043679///axon terminus+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane+++GO:0097444///spine apparatus+++GO:0098992///neuronal dense core vesicle+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004930///G protein-coupled receptor activity+++GO:0004985///opioid receptor activity+++GO:0005515///protein binding+++GO:0033612///receptor serine/threonine kinase binding+++GO:0038046///enkephalin receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0008344///adult locomotory behavior+++GO:0010629///negative regulation of gene expression+++GO:0031333///negative regulation of protein complex assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038003///opioid receptor signaling pathway+++GO:0042755///eating behavior+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051924///regulation of calcium ion transport+++GO:0051930///regulation of sensory perception of pain+++GO:0071363///cellular response to growth factor stimulus+++GO:0071456///cellular response to hypoxia+++GO:0097237///cellular response to toxic substance+++GO:0098926///postsynaptic signal transduction+++GO:0098928///presynaptic signal transduction 18387 18387 'Oprk1' mRNA 3 0 0 0.04 0 0 0 0 0.02 0.013333333 0.006666667 0 0 2 1 0.666666667 0.888377162 -0.566201992 04080///Neuroactive ligand-receptor interaction GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004985///opioid receptor activity+++GO:0033612///receptor serine/threonine kinase binding+++GO:0038048///dynorphin receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007610///behavior+++GO:0007626///locomotory behavior+++GO:0009314///response to radiation+++GO:0019233///sensory perception of pain+++GO:0031635///adenylate cyclase-inhibiting opioid receptor signaling pathway+++GO:0032868///response to insulin+++GO:0033603///positive regulation of dopamine secretion+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0038003///opioid receptor signaling pathway+++GO:0040017///positive regulation of locomotion+++GO:0042220///response to cocaine+++GO:0042711///maternal behavior+++GO:0042755///eating behavior+++GO:0043278///response to morphine+++GO:0043627///response to estrogen+++GO:0044849///estrous cycle+++GO:0045471///response to ethanol+++GO:0046877///regulation of saliva secretion+++GO:0048148///behavioral response to cocaine+++GO:0050951///sensory perception of temperature stimulus+++GO:0051607///defense response to virus+++GO:0051930///regulation of sensory perception of pain+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071333///cellular response to glucose stimulus+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903937///response to acrylamide+++GO:1904000///positive regulation of eating behavior+++GO:1990708///conditioned place preference 18389 18389 'Oprl1' mRNA 11 2 2 0.22 0.04 0.04 0.09 0.09 0.22 0.1 0.133333333 5 5 13 5 7.666666667 0.655707392 0.619957857 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection GO:0001626///nociceptin receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004985///opioid receptor activity+++GO:0008022///protein C-terminus binding+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007610///behavior+++GO:0019233///sensory perception of pain+++GO:0032355///response to estradiol+++GO:0035810///positive regulation of urine volume+++GO:0038003///opioid receptor signaling pathway+++GO:0042755///eating behavior+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0044849///estrous cycle+++GO:0045776///negative regulation of blood pressure+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051930///regulation of sensory perception of pain+++GO:0060454///positive regulation of gastric acid secretion+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1904058///positive regulation of sensory perception of pain+++GO:1904059///regulation of locomotor rhythm+++GO:1990708///conditioned place preference 18390 18390 'Oprm1' mRNA 0 1 0 0 0.03 0 0.02 0 0.02 0.01 0.013333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873430513 04080///Neuroactive ligand-receptor interaction+++04915///Estrogen signaling pathway+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0032839///dendrite cytoplasm+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0097444///spine apparatus+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0004979///beta-endorphin receptor activity+++GO:0004985///opioid receptor activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0031005///filamin binding+++GO:0031681///G-protein beta-subunit binding+++GO:0038047///morphine receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0007626///locomotory behavior+++GO:0009314///response to radiation+++GO:0019233///sensory perception of pain+++GO:0031635///adenylate cyclase-inhibiting opioid receptor signaling pathway+++GO:0032094///response to food+++GO:0032100///positive regulation of appetite+++GO:0032496///response to lipopolysaccharide+++GO:0035176///social behavior+++GO:0038003///opioid receptor signaling pathway+++GO:0042060///wound healing+++GO:0042220///response to cocaine+++GO:0042755///eating behavior+++GO:0043278///response to morphine+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0044849///estrous cycle+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045471///response to ethanol+++GO:0048149///behavioral response to ethanol+++GO:0050769///positive regulation of neurogenesis+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051930///regulation of sensory perception of pain+++GO:0060079///excitatory postsynaptic potential+++GO:0061358///negative regulation of Wnt protein secretion+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0070848///response to growth factor+++GO:0071315///cellular response to morphine+++GO:0080135///regulation of cellular response to stress+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000310///regulation of NMDA receptor activity 18391 18391 'Sigmar1' mRNA 1109 1135 918 39.57 39.88 34.72 56.69 55.5 54.63 38.05666667 55.60666667 1828 1747 1699 1054 1758 2.30E-19 0.729552049 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane GO:0004985///opioid receptor activity+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0006869///lipid transport+++GO:0007399///nervous system development+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0038003///opioid receptor signaling pathway+++GO:0043523///regulation of neuron apoptotic process+++GO:0070207///protein homotrimerization 18392 18392 'Orc1' mRNA 12 10 12 0.22 0.18 0.23 0.9 0.78 1.14 0.21 0.94 57 48 70 11.33333333 58.33333333 3.06E-07 2.349986565 04110///Cell cycle "GO:0000781///chromosome, telomeric region+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0070318///positive regulation of G0 to G1 transition 18393 18393 'Orc2' mRNA 695 665 635 10.7 10.18 10.28 9.44 8.24 8.37 10.38666667 8.683333333 703 607 610 665 640 0.624001461 -0.067603553 04110///Cell cycle "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0000808///origin recognition complex+++GO:0000939///condensed chromosome inner kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005813///centrosome" GO:0003688///DNA replication origin binding GO:0006260///DNA replication 18399 18399 'Slc22a6' mRNA 42 73 47 0.56 0.96 0.67 0.9 1.14 0.72 0.73 0.92 77 96 60 54 77.66666667 0.166066851 0.519077836 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0032991///protein-containing complex GO:0005452///inorganic anion exchanger activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0031404///chloride ion binding+++GO:0042802///identical protein binding GO:0006820///anion transport+++GO:0015698///inorganic anion transport+++GO:0015711///organic anion transport+++GO:0015742///alpha-ketoglutarate transport+++GO:0031427///response to methotrexate+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport+++GO:0097254///renal tubular secretion+++GO:0098656///anion transmembrane transport 18400 18400 'Slc22a18' mRNA 174 161 144 7.05 6.32 6.13 5.21 6.24 4.86 6.5 5.436666667 146 169 133 159.6666667 149.3333333 0.704438957 -0.105043401 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0031625///ubiquitin protein ligase binding GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0015711///organic anion transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:1990961///drug transmembrane export 18405 18405 'Orm1' mRNA 2 6 3 0.18 0.52 0.28 0.62 0.71 1.2 0.326666667 0.843333333 8 9 15 3.666666667 10.66666667 0.143948701 1.537597128 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0036094///small molecule binding GO:0002682///regulation of immune system process+++GO:0006953///acute-phase response 18406 18406 'Orm2' mRNA 20 23 15 1.78 1.99 1.4 1.93 2.98 2 1.723333333 2.303333333 25 38 25 19.33333333 29.33333333 0.302709072 0.599284809 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0036094///small molecule binding GO:0002682///regulation of immune system process+++GO:0006953///acute-phase response 18407 18407 'Orm3' mRNA 0 0 1 0 0 0.03 0.08 0.29 0 0.01 0.123333333 3 5 0 0.333333333 2.666666667 0.288454041 2.887711424 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0036094///small molecule binding GO:0002682///regulation of immune system process+++GO:0006953///acute-phase response 18408 18408 'Slc25a15' mRNA 266 325 251 4.16 4.97 4.19 2.87 3.93 3.33 4.44 3.376666667 213 284 238 280.6666667 245 0.322372646 -0.201979323 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000064///L-ornithine transmembrane transporter activity GO:1990575///mitochondrial L-ornithine transmembrane transport 18412 18412 'Sqstm1' mRNA 11055.02 11249.98 10589.01 309.49 309.68 313.91 404.73 383.84 405.51 311.0266667 398.0266667 16579.54 15376.87 16064.18 10964.67 16006.86333 1.17E-29 0.533911347 04137///Mitophagy - animal+++04140///Autophagy - animal+++04217///Necroptosis+++04218///Cellular senescence+++04380///Osteoclast differentiation+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05418///Fluid shear stress and atherosclerosis GO:0000407///phagophore assembly site+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016234///inclusion body+++GO:0016235///aggresome+++GO:0016605///PML body+++GO:0030017///sarcomere+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044753///amphisome+++GO:0044754///autolysosome+++GO:0097225///sperm midpiece+++GO:0097413///Lewy body GO:0003712///transcription coregulator activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000423///mitophagy+++GO:0001659///temperature homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006606///protein import into nucleus+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0007032///endosome organization+++GO:0016236///macroautophagy+++GO:0030154///cell differentiation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0035973///aggrephagy+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0061635///regulation of protein complex stability+++GO:0061912///selective autophagy+++GO:0070342///brown fat cell proliferation+++GO:0097009///energy homeostasis+++GO:0098780///response to mitochondrial depolarisation+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905719///protein localization to perinuclear region of cytoplasm 18413 18413 'Osm' mRNA 24 14 22 0.72 0.41 0.7 7.02 6.34 6.88 0.61 6.746666667 269 237 255 20 253.6666667 3.90E-41 3.65062431 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005147///oncostatin-M receptor binding+++GO:0008083///growth factor activity GO:0006955///immune response+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0007422///peripheral nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0009408///response to heat+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0032740///positive regulation of interleukin-17 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0040008///regulation of growth+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043410///positive regulation of MAPK cascade+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046888///negative regulation of hormone secretion+++GO:0048266///behavioral response to pain+++GO:0050729///positive regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:2001235///positive regulation of apoptotic signaling pathway 18414 18414 'Osmr' mRNA 223 241 204 2.45 2.62 2.39 26.14 24.08 25.56 2.486666667 25.26 2722 2449 2578 222.6666667 2583 0 3.525318347 04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway GO:0005887///integral component of plasma membrane+++GO:0005900///oncostatin-M receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004923///leukemia inhibitory factor receptor activity+++GO:0004924///oncostatin-M receptor activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0019838///growth factor binding+++GO:0019955///cytokine binding GO:0007166///cell surface receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0048861///leukemia inhibitory factor signaling pathway 18415 18415 'Hspa4l' mRNA 4903 5039 4599.06 50.88 50.7 49.95 31.66 29.83 30.99 50.51 30.82666667 3649 3375.45 3473.49 4847.02 3499.313333 2.41E-18 -0.481404126 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0006457///protein folding+++GO:0006986///response to unfolded protein 18417 18417 'Cldn11' mRNA 2665 2742 2220 81.66 82.8 72.17 80.8 76.2 79.91 78.87666667 78.97 3031 2790 2901 2542.333333 2907.333333 0.012026584 0.184991372 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005811///lipid droplet+++GO:0005883///neurofilament+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0043209///myelin sheath+++GO:0045178///basal part of cell+++GO:0070160///tight junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007283///spermatogenesis+++GO:0008366///axon ensheathment+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly+++GO:0120192///tight junction assembly 18419 18419 'Otog' mRNA 92165 92992 83400 480.39 476.32 461.08 118.19 112.35 118.39 472.5966667 116.31 26115 24262 25346 89519 25241 0 -1.837006014 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031012///extracellular matrix GO:0005198///structural molecule activity+++GO:0046556///alpha-L-arabinofuranosidase activity GO:0007605///sensory perception of sound+++GO:0008344///adult locomotory behavior+++GO:0046373///L-arabinose metabolic process 18423 18423 'Otx1' mRNA 164 184 167 3.18 3.54 3.46 0.2 0.35 0.39 3.393333333 0.313333333 12 20 22 171.6666667 18 2.64E-26 -3.262761924 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0022037///metencephalon development+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0042472///inner ear morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048852///diencephalon morphogenesis" 18424 18424 'Otx2' mRNA 166 149 160 4.16 3.7 4.24 0.46 0.36 0.13 4.033333333 0.316666667 23 17 7 158.3333333 15.66666667 5.63E-23 -3.353078033 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0030426///growth cone+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001708///cell fate specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007492///endoderm development+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0021978///telencephalon regionalization+++GO:0022037///metencephalon development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0032525///somite rostral/caudal axis specification+++GO:0040019///positive regulation of embryonic development+++GO:0042472///inner ear morphogenesis+++GO:0042706///eye photoreceptor cell fate commitment+++GO:0045165///cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048382///mesendoderm development+++GO:0048663///neuron fate commitment+++GO:0048664///neuron fate determination+++GO:0048709///oligodendrocyte differentiation+++GO:0048852///diencephalon morphogenesis+++GO:0048856///anatomical structure development+++GO:0065003///protein-containing complex assembly+++GO:0071542///dopaminergic neuron differentiation+++GO:0090009///primitive streak formation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000543///positive regulation of gastrulation" 18426 18426 'Ovol1' mRNA 11 4 14 0.25 0.09 0.34 0.1 0.34 0.2 0.226666667 0.213333333 5 19 11 9.666666667 11.66666667 0.831110956 0.252668676 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007498///mesoderm development+++GO:0008544///epidermis development+++GO:0009913///epidermal cell differentiation+++GO:0043588///skin development+++GO:0051729///germline cell cycle switching, mitotic to meiotic cell cycle+++GO:1901994///negative regulation of meiotic cell cycle phase transition+++GO:2000647///negative regulation of stem cell proliferation" 18430 18430 'Oxtr' mRNA 13 16 12 0.14 0.16 0.15 0.05 0 0.01 0.15 0.02 6 0 1 13.66666667 2.333333333 0.018780694 -2.572535663 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04921///Oxytocin signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0004930///G protein-coupled receptor activity+++GO:0004990///oxytocin receptor activity+++GO:0005000///vasopressin receptor activity+++GO:0017046///peptide hormone binding+++GO:0042277///peptide binding "GO:0001967///suckling behavior+++GO:0001975///response to amphetamine+++GO:0001992///regulation of systemic arterial blood pressure by vasopressin+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0007613///memory+++GO:0010701///positive regulation of norepinephrine secretion+++GO:0014070///response to organic cyclic compound+++GO:0021537///telencephalon development+++GO:0030431///sleep+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0034059///response to anoxia+++GO:0034097///response to cytokine+++GO:0035176///social behavior+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0042711///maternal behavior+++GO:0042713///sperm ejaculation+++GO:0042755///eating behavior+++GO:0043434///response to peptide hormone+++GO:0044058///regulation of digestive system process+++GO:0044849///estrous cycle+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0048545///response to steroid hormone+++GO:0048565///digestive tract development+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060137///maternal process involved in parturition+++GO:0060406///positive regulation of penile erection+++GO:0060455///negative regulation of gastric acid secretion+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0120162///positive regulation of cold-induced thermogenesis" 18431 18431 'Oca2' mRNA 41 57 41 0.72 0.98 0.76 0.14 0.12 0.08 0.82 0.113333333 9 8 5 46.33333333 7.333333333 7.50E-07 -2.668257101 GO:0005765///lysosomal membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane GO:0007286///spermatid development+++GO:0008283///cell proliferation+++GO:0030318///melanocyte differentiation+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0055085///transmembrane transport 18432 18432 'Mybbp1a' mRNA 1486 1502 1425.88 18.2 18.09 18.52 18.91 18.5 18.43 18.27 18.61333333 1778 1699 1678 1471.293333 1718.333333 0.005365501 0.212496591 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0042564///NLS-dependent protein nuclear import complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0022904///respiratory electron transport chain+++GO:0032922///circadian regulation of gene expression+++GO:0042149///cellular response to glucose starvation+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:2000210///positive regulation of anoikis" 18436 18436 'P2rx1' mRNA 2 4 7 0.05 0.09 0.17 0.46 0.04 0.04 0.103333333 0.18 23 2 2 4.333333333 9 0.475916762 1.001502685 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04611///Platelet activation GO:0005639///integral component of nuclear inner membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0000166///nucleotide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0043924///suramin binding+++GO:0044877///protein-containing complex binding+++GO:0097159///organic cyclic compound binding "GO:0002554///serotonin secretion by platelet+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0006811///ion transport+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006940///regulation of smooth muscle contraction+++GO:0007320///insemination+++GO:0008217///regulation of blood pressure+++GO:0010033///response to organic substance+++GO:0019228///neuronal action potential+++GO:0019229///regulation of vasoconstriction+++GO:0030168///platelet activation+++GO:0033198///response to ATP+++GO:0034220///ion transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0043270///positive regulation of ion transport+++GO:0046513///ceramide biosynthetic process+++GO:0051924///regulation of calcium ion transport+++GO:0060079///excitatory postsynaptic potential+++GO:0098655///cation transmembrane transport+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:2000300///regulation of synaptic vesicle exocytosis" 18438 18438 'P2rx4' mRNA 1118 1159 1117 23.01 23.52 24.54 55.22 57.64 59.06 23.69 57.30666667 3085 3138 3193 1131.333333 3138.666667 3.52E-97 1.460661053 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005639///integral component of nuclear inner membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044297///cell body+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0000166///nucleotide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005507///copper ion binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0099604///ligand-gated calcium channel activity GO:0002028///regulation of sodium ion transport+++GO:0002931///response to ischemia+++GO:0006809///nitric oxide biosynthetic process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0019722///calcium-mediated signaling+++GO:0033198///response to ATP+++GO:0034220///ion transmembrane transport+++GO:0034405///response to fluid shear stress+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0042311///vasodilation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0048266///behavioral response to pain+++GO:0048678///response to axon injury+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050920///regulation of chemotaxis+++GO:0050975///sensory perception of touch+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051899///membrane depolarization+++GO:0055117///regulation of cardiac muscle contraction+++GO:0055119///relaxation of cardiac muscle+++GO:0060079///excitatory postsynaptic potential+++GO:0070588///calcium ion transmembrane transport+++GO:0071294///cellular response to zinc ion+++GO:0071318///cellular response to ATP+++GO:0097190///apoptotic signaling pathway+++GO:0098655///cation transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:1904141///positive regulation of microglial cell migration+++GO:2001028///positive regulation of endothelial cell chemotaxis 18439 18439 'P2rx7' mRNA 447 353 357 10.33 7.95 8.29 22.04 26.17 23.93 8.856666667 24.04666667 1142 1137 1203 385.6666667 1160.666667 3.06E-47 1.579075941 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04621///NOD-like receptor signaling pathway GO:0005639///integral component of nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031594///neuromuscular junction+++GO:0032059///bleb+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0000287///magnesium ion binding+++GO:0001530///lipopolysaccharide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0015267///channel activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0097110///scaffold protein binding GO:0000187///activation of MAPK activity+++GO:0000902///cell morphogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001845///phagolysosome assembly+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002028///regulation of sodium ion transport+++GO:0006468///protein phosphorylation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006649///phospholipid transfer to membrane+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006884///cell volume homeostasis+++GO:0006900///vesicle budding from membrane+++GO:0006954///inflammatory response+++GO:0007005///mitochondrion organization+++GO:0007009///plasma membrane organization+++GO:0007166///cell surface receptor signaling pathway+++GO:0008219///cell death+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0010033///response to organic substance+++GO:0010043///response to zinc ion+++GO:0010467///gene expression+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010628///positive regulation of gene expression+++GO:0012501///programmed cell death+++GO:0014049///positive regulation of glutamate secretion+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0014070///response to organic cyclic compound+++GO:0016079///synaptic vesicle exocytosis+++GO:0016485///protein processing+++GO:0017121///phospholipid scrambling+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0030163///protein catabolic process+++GO:0030501///positive regulation of bone mineralization+++GO:0031668///cellular response to extracellular stimulus+++GO:0032060///bleb assembly+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032963///collagen metabolic process+++GO:0033198///response to ATP+++GO:0034220///ion transmembrane transport+++GO:0034405///response to fluid shear stress+++GO:0034767///positive regulation of ion transmembrane transport+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0042098///T cell proliferation+++GO:0042493///response to drug+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043132///NAD transport+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0045332///phospholipid translocation+++GO:0045778///positive regulation of ossification+++GO:0045779///negative regulation of bone resorption+++GO:0045794///negative regulation of cell volume+++GO:0045821///positive regulation of glycolytic process+++GO:0046513///ceramide biosynthetic process+++GO:0046931///pore complex assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050714///positive regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051495///positive regulation of cytoskeleton organization+++GO:0051592///response to calcium ion+++GO:0051602///response to electrical stimulus+++GO:0051899///membrane depolarization+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0060079///excitatory postsynaptic potential+++GO:0070230///positive regulation of lymphocyte apoptotic process+++GO:0071359///cellular response to dsRNA+++GO:0071407///cellular response to organic cyclic compound+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072593///reactive oxygen species metabolic process+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0098655///cation transmembrane transport+++GO:0099161///regulation of presynaptic dense core granule exocytosis+++GO:1904172///positive regulation of bleb assembly+++GO:1904669///ATP export 18440 18440 'P2rx6' mRNA 556 636 542 13.43 15.03 13.85 7.13 7.24 7.55 14.10333333 7.306666667 342 339 350 578 343.6666667 3.62E-10 -0.759969951 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005639///integral component of nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043235///receptor complex+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0000166///nucleotide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0005524///ATP binding+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0033198///response to ATP+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0060079///excitatory postsynaptic potential+++GO:0098655///cation transmembrane transport 18441 18441 'P2ry1' mRNA 692 716 694 10.11 10.12 10.73 6.9 7.45 7.62 10.32 7.323333333 545 582 583 700.6666667 570 0.005775066 -0.309109383 04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04611///Platelet activation+++04742///Taste transduction GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0044297///cell body+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0000166///nucleotide binding+++GO:0001621///ADP receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005524///ATP binding+++GO:0031686///A1 adenosine receptor binding+++GO:0043531///ADP binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045031///ATP-activated adenosine receptor activity+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0001973///adenosine receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007568///aging+++GO:0008347///glial cell migration+++GO:0008360///regulation of cell shape+++GO:0009612///response to mechanical stimulus+++GO:0010469///regulation of signaling receptor activity+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0019233///sensory perception of pain+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030168///platelet activation+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0042060///wound healing+++GO:0042755///eating behavior+++GO:0043270///positive regulation of ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046887///positive regulation of hormone secretion+++GO:0051100///negative regulation of binding+++GO:0060406///positive regulation of penile erection+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070848///response to growth factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0071415///cellular response to purine-containing compound+++GO:0072659///protein localization to plasma membrane+++GO:0090075///relaxation of muscle+++GO:0097746///regulation of blood vessel diameter+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 18442 18442 'P2ry2' mRNA 1199 1156 1100 22.13 21.06 21.5 16.81 17.01 16.69 21.56333333 16.83666667 1052 1036 1007 1151.666667 1031.666667 0.061616963 -0.169903261 04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0004930///G protein-coupled receptor activity+++GO:0005524///ATP binding+++GO:0031686///A1 adenosine receptor binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045030///UTP-activated nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010976///positive regulation of neuron projection development+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0019233///sensory perception of pain+++GO:0030279///negative regulation of ossification+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032722///positive regulation of chemokine production+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0060406///positive regulation of penile erection+++GO:0070257///positive regulation of mucus secretion+++GO:0097746///regulation of blood vessel diameter+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 18451 18451 'P4ha1' mRNA 1939 2046 1778 25.88 26.86 25.17 28.27 25.74 27.23 25.97 27.08 2438 2168 2274 1921 2293.333333 6.36E-04 0.244875836 00330///Arginine and proline metabolism GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016222///procollagen-proline 4-dioxygenase complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0019511///peptidyl-proline hydroxylation+++GO:0030199///collagen fibril organization 18452 18452 'P4ha2' mRNA 49 71 85 1.21 1.72 2.22 5.08 5.11 4.45 1.716666667 4.88 237 233 201 68.33333333 223.6666667 1.36E-12 1.692410295 00330///Arginine and proline metabolism GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016222///procollagen-proline 4-dioxygenase complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0019511///peptidyl-proline hydroxylation 18453 18453 'P4hb' mRNA 7650 7778 7877 147.38 147.48 160.98 265.53 251.41 253.91 151.9466667 256.95 15857 14663 14682 7768.333333 15067.33333 1.04E-61 0.941810666 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016222///procollagen-proline 4-dioxygenase complex+++GO:0030027///lamellipodium+++GO:0032991///protein-containing complex+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0042470///melanosome GO:0003756///protein disulfide isomerase activity+++GO:0003779///actin binding+++GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0016972///thiol oxidase activity+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity GO:0006457///protein folding+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045785///positive regulation of cell adhesion+++GO:0046598///positive regulation of viral entry into host cell+++GO:0071456///cellular response to hypoxia+++GO:0098761///cellular response to interleukin-7+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902175///regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 18457 18457 'Bloc1s6' mRNA 1052.01 1156 1012 16.38 17.7 16.71 16.23 15.44 14.78 16.93 15.48333333 1200 1115 1058 1073.336667 1124.333333 0.622474721 0.056007825 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030133///transport vesicle+++GO:0031083///BLOC-1 complex+++GO:0031201///SNARE complex+++GO:0036064///ciliary basal body+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding GO:0001822///kidney development+++GO:0001944///vasculature development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006531///aspartate metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006541///glutamine metabolic process+++GO:0006547///histidine metabolic process+++GO:0006553///lysine metabolic process+++GO:0006558///L-phenylalanine metabolic process+++GO:0006568///tryptophan metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006906///vesicle fusion+++GO:0007010///cytoskeleton organization+++GO:0007032///endosome organization+++GO:0007596///blood coagulation+++GO:0007613///memory+++GO:0008089///anterograde axonal transport+++GO:0009306///protein secretion+++GO:0010467///gene expression+++GO:0016197///endosomal transport+++GO:0021542///dentate gyrus development+++GO:0021854///hypothalamus development+++GO:0030036///actin cytoskeleton organization+++GO:0030318///melanocyte differentiation+++GO:0031175///neuron projection development+++GO:0032402///melanosome transport+++GO:0032816///positive regulation of natural killer cell activation+++GO:0033299///secretion of lysosomal enzymes+++GO:0035641///locomotory exploration behavior+++GO:0035646///endosome to melanosome transport+++GO:0042745///circadian sleep/wake cycle+++GO:0043473///pigmentation+++GO:0046085///adenosine metabolic process+++GO:0046907///intracellular transport+++GO:0048490///anterograde synaptic vesicle transport+++GO:0048813///dendrite morphogenesis+++GO:0050942///positive regulation of pigment cell differentiation+++GO:0055088///lipid homeostasis+++GO:0060155///platelet dense granule organization+++GO:0061025///membrane fusion+++GO:1903441///protein localization to ciliary membrane 18458 18458 'Pabpc1' mRNA 5049 4882 3717 102.17 97.79 80.37 116.66 108.85 113.99 93.44333333 113.1666667 6546 6007 6215 4549.333333 6256 6.65E-09 0.45312184 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0071013///catalytic step 2 spliceosome+++GO:1990124///messenger ribonucleoprotein complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:0045070///positive regulation of viral genome replication+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:2000623///negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 18472 18472 'Pafah1b1' mRNA 877 834 560 8.46 7.91 5.73 7.52 7.38 7.14 7.366666667 7.346666667 897 861 826 757 861.3333333 0.206777169 0.182502935 00565///Ether lipid metabolism GO:0000235///astral microtubule+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005881///cytoplasmic microtubule+++GO:0005938///cell cortex+++GO:0008247///1-alkyl-2-acetylglycerophosphocholine esterase complex+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0031514///motile cilium+++GO:0031965///nuclear membrane+++GO:0031982///vesicle+++GO:0032420///stereocilium+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0090724///central region of growth cone+++GO:0097730///non-motile cilium+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0046982///protein heterodimerization activity+++GO:0051010///microtubule plus-end binding+++GO:0051219///phosphoprotein binding+++GO:0070840///dynein complex binding GO:0000132///establishment of mitotic spindle orientation+++GO:0000226///microtubule cytoskeleton organization+++GO:0001667///ameboidal-type cell migration+++GO:0001675///acrosome assembly+++GO:0001764///neuron migration+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0006629///lipid metabolic process+++GO:0007017///microtubule-based process+++GO:0007049///cell cycle+++GO:0007097///nuclear migration+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007399///nervous system development+++GO:0007405///neuroblast proliferation+++GO:0007420///brain development+++GO:0007611///learning or memory+++GO:0008090///retrograde axonal transport+++GO:0008344///adult locomotory behavior+++GO:0009306///protein secretion+++GO:0010977///negative regulation of neuron projection development+++GO:0016042///lipid catabolic process+++GO:0016477///cell migration+++GO:0017145///stem cell division+++GO:0019226///transmission of nerve impulse+++GO:0021540///corpus callosum morphogenesis+++GO:0021766///hippocampus development+++GO:0021819///layer formation in cerebral cortex+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021987///cerebral cortex development+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0031023///microtubule organizing center organization+++GO:0036035///osteoclast development+++GO:0038026///reelin-mediated signaling pathway+++GO:0040019///positive regulation of embryonic development+++GO:0042249///establishment of planar polarity of embryonic epithelium+++GO:0043087///regulation of GTPase activity+++GO:0043622///cortical microtubule organization+++GO:0045773///positive regulation of axon extension+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046329///negative regulation of JNK cascade+++GO:0047496///vesicle transport along microtubule+++GO:0048854///brain morphogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0051012///microtubule sliding+++GO:0051081///nuclear envelope disassembly+++GO:0051130///positive regulation of cellular component organization+++GO:0051301///cell division+++GO:0051660///establishment of centrosome localization+++GO:0051661///maintenance of centrosome location+++GO:0060117///auditory receptor cell development+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0090102///cochlea development+++GO:0090176///microtubule cytoskeleton organization involved in establishment of planar polarity+++GO:2000574///regulation of microtubule motor activity 18475 18475 'Pafah1b2' mRNA 3530 3645 3768 44.56 45.19 50.47 39.5 39.86 37.52 46.74 38.96 3589 3533 3298 3647.666667 3473.333333 0.316979376 -0.084657902 00565///Ether lipid metabolism GO:0001650///fibrillar center+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008247///1-alkyl-2-acetylglycerophosphocholine esterase complex GO:0003674///molecular_function+++GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0047179///platelet-activating factor acetyltransferase activity GO:0006629///lipid metabolic process+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0008150///biological_process+++GO:0016042///lipid catabolic process+++GO:0016239///positive regulation of macroautophagy 18476 18476 'Pafah1b3' mRNA 996 963 928 71.01 68.41 70.38 43.43 44.72 46.17 69.93333333 44.77333333 704 700 721 962.3333333 708.3333333 1.40E-06 -0.453371547 00565///Ether lipid metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008247///1-alkyl-2-acetylglycerophosphocholine esterase complex GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0047179///platelet-activating factor acetyltransferase activity GO:0006629///lipid metabolic process+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0016042///lipid catabolic process 18477 18477 'Prdx1' mRNA 11834 12317 11790 497.91 511.3 526.29 747.64 755.42 750.22 511.8333333 751.0933333 20407 20117 19808 11980.33333 20110.66667 2.01E-50 0.73526328 04146///Peroxisome+++05146///Amoebiasis GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0051920///peroxiredoxin activity GO:0000302///response to reactive oxygen species+++GO:0006979///response to oxidative stress+++GO:0008283///cell proliferation+++GO:0019430///removal of superoxide radicals+++GO:0030101///natural killer cell activation+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033554///cellular response to stress+++GO:0034101///erythrocyte homeostasis+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042744///hydrogen peroxide catabolic process+++GO:0045321///leukocyte activation+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification+++GO:1901222///regulation of NIK/NF-kappaB signaling 18478 18478 'Pah' mRNA 1 0 0 0.03 0 0 0 0 0.07 0.01 0.023333333 0 0 3 0.333333333 1 0.750011424 1.475773177 "00360///Phenylalanine metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis+++00790///Folate biosynthesis+++01230///Biosynthesis of amino acids" "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0004505///phenylalanine 4-monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016597///amino acid binding+++GO:0016714///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" "GO:0006558///L-phenylalanine metabolic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006571///tyrosine biosynthetic process+++GO:0008152///metabolic process+++GO:0009072///aromatic amino acid family metabolic process+++GO:0018126///protein hydroxylation+++GO:0019293///tyrosine biosynthetic process, by oxidation of phenylalanine" 18479 18479 'Pak1' mRNA 1093 1127 829 18.71 18.97 15.48 14.55 16.04 18.25 17.72 16.28 955 1037 1172 1016.333333 1054.666667 0.751368437 0.048817975 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04360///Axon guidance+++04392///Hippo signaling pathway - multiple species+++04510///Focal adhesion+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05170///Human immunodeficiency virus 1 infection+++05205///Proteoglycans in cancer+++05211///Renal cell carcinoma GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031965///nuclear membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding "GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006338///chromatin remodeling+++GO:0006468///protein phosphorylation+++GO:0006887///exocytosis+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007528///neuromuscular junction development+++GO:0008152///metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010763///positive regulation of fibroblast migration+++GO:0016310///phosphorylation+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0019226///transmission of nerve impulse+++GO:0021549///cerebellum development+++GO:0021764///amygdala development+++GO:0030010///establishment of cell polarity+++GO:0030335///positive regulation of cell migration+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032147///activation of protein kinase activity+++GO:0032869///cellular response to insulin stimulus+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0042060///wound healing+++GO:0043113///receptor clustering+++GO:0043408///regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045773///positive regulation of axon extension+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048812///neuron projection morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:0060996///dendritic spine development+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0061534///gamma-aminobutyric acid secretion, neurotransmission+++GO:0061535///glutamate secretion, neurotransmission+++GO:0071407///cellular response to organic cyclic compound+++GO:0090063///positive regulation of microtubule nucleation+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0098597///observational learning+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration" 18481 18481 'Pak3' mRNA 3548 3615 3553 21.37 21.42 22.7 2.93 2.95 3.03 21.83 2.97 555 545 560 3572 553.3333333 1.32E-286 -2.702994295 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05170///Human immunodeficiency virus 1 infection+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding "GO:0000165///MAPK cascade+++GO:0000902///cell morphogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001841///neural tube formation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003157///endocardium development+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007417///central nervous system development+++GO:0008152///metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010763///positive regulation of fibroblast migration+++GO:0010975///regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0016358///dendrite development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030216///keratinocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032092///positive regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035329///hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0046621///negative regulation of organ growth+++GO:0046777///protein autophosphorylation+++GO:0050770///regulation of axonogenesis+++GO:0050821///protein stabilization+++GO:0051262///protein tetramerization+++GO:0060215///primitive hemopoiesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development+++GO:0060996///dendritic spine development+++GO:0060997///dendritic spine morphogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071407///cellular response to organic cyclic compound+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904237///positive regulation of substrate-dependent cell migration, cell attachment to substrate+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:2000573///positive regulation of DNA biosynthetic process" 18483 18483 'Palm' mRNA 2127 2226 1473 46.31 47.45 34 28.46 37.96 35.34 42.58666667 33.92 1516 1983 1830 1942 1776.333333 0.379861276 -0.129000061 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031527///filopodium membrane+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0044309///neuron spine+++GO:0045202///synapse GO:0031750///D3 dopamine receptor binding GO:0007010///cytoskeleton organization+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0008104///protein localization+++GO:0008360///regulation of cell shape+++GO:0051491///positive regulation of filopodium assembly+++GO:0060074///synapse maturation+++GO:0060160///negative regulation of dopamine receptor signaling pathway+++GO:0060999///positive regulation of dendritic spine development+++GO:0071257///cellular response to electrical stimulus+++GO:0072659///protein localization to plasma membrane 18484 18484 'Pam' mRNA 2841 2685 2010 39.97 37.01 29.99 32.88 36.41 39.14 35.65666667 36.14333333 2700 2917 3123 2512 2913.333333 0.044188568 0.209722086 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0004504///peptidylglycine monooxygenase activity+++GO:0004598///peptidylamidoglycolate lyase activity+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016715///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen+++GO:0016829///lyase activity+++GO:0019901///protein kinase binding+++GO:0031418///L-ascorbic acid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0001519///peptide amidation+++GO:0001666///response to hypoxia+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006518///peptide metabolic process+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0009268///response to pH+++GO:0009404///toxin metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010043///response to zinc ion+++GO:0018032///protein amidation+++GO:0019538///protein metabolic process+++GO:0022602///ovulation cycle process+++GO:0032355///response to estradiol+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042476///odontogenesis+++GO:0042493///response to drug+++GO:0046688///response to copper ion+++GO:0050708///regulation of protein secretion+++GO:0051384///response to glucocorticoid+++GO:0060135///maternal process involved in female pregnancy+++GO:0060173///limb development 18488 18488 'Cntn3' mRNA 107 99 125 1.11 1.03 1.36 0.53 0.42 0.78 1.166666667 0.576666667 59 46 84 110.3333333 63 0.007733204 -0.826235709 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection GO:0007155///cell adhesion+++GO:0007399///nervous system development 18489 18489 'Reg3b' mRNA 49 47 40 4.48 4.26 3.88 0.64 0.74 1.32 4.206666667 0.9 8 9 16 45.33333333 11 5.10E-05 -2.050240486 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0042588///zymogen granule+++GO:0045177///apical part of cell+++GO:0062023///collagen-containing extracellular matrix GO:0019838///growth factor binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0070492///oligosaccharide binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044278///cell wall disruption in other organism+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0060548///negative regulation of cell death+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death 18491 18491 'Pappa' mRNA 15 7 9 0.07 0.03 0.05 0.39 0.22 0.31 0.05 0.306666667 95 52 72 10.33333333 73 1.34E-09 2.804937768 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007565///female pregnancy+++GO:0032354///response to follicle-stimulating hormone+++GO:0051384///response to glucocorticoid 18504 18504 'Pax2' mRNA 349 413 162 4.84 5.64 2.38 1.34 1.71 1.45 4.286666667 1.5 111 139 117 308 122.3333333 3.58E-07 -1.32419031 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005764///lysosome+++GO:0005815///microtubule organizing center+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0034451///centriolar satellite "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001709///cell fate determination+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0001843///neural tube closure+++GO:0002072///optic cup morphogenesis involved in camera-type eye development+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0003406///retinal pigment epithelium development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007501///mesodermal cell fate specification+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0010001///glial cell differentiation+++GO:0021554///optic nerve development+++GO:0021631///optic nerve morphogenesis+++GO:0021633///optic nerve structural organization+++GO:0021650///vestibulocochlear nerve formation+++GO:0030154///cell differentiation+++GO:0031016///pancreas development+++GO:0031667///response to nutrient levels+++GO:0035566///regulation of metanephros size+++GO:0035799///ureter maturation+++GO:0039003///pronephric field specification+++GO:0042472///inner ear morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0043067///regulation of programmed cell death+++GO:0043069///negative regulation of programmed cell death+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048793///pronephros development+++GO:0048854///brain morphogenesis+++GO:0048856///anatomical structure development+++GO:0048863///stem cell differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060231///mesenchymal to epithelial transition+++GO:0061205///paramesonephric duct development+++GO:0061360///optic chiasma development+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071300///cellular response to retinoic acid+++GO:0071333///cellular response to glucose stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071542///dopaminergic neuron differentiation+++GO:0072075///metanephric mesenchyme development+++GO:0072108///positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072164///mesonephric tubule development+++GO:0072172///mesonephric tubule formation+++GO:0072177///mesonephric duct development+++GO:0072179///nephric duct formation+++GO:0072189///ureter development+++GO:0072197///ureter morphogenesis+++GO:0072205///metanephric collecting duct development+++GO:0072207///metanephric epithelium development+++GO:0072221///metanephric distal convoluted tubule development+++GO:0072289///metanephric nephron tubule formation+++GO:0072300///positive regulation of metanephric glomerulus development+++GO:0072305///negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0072593///reactive oxygen species metabolic process+++GO:0090102///cochlea development+++GO:0090103///cochlea morphogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1900212///negative regulation of mesenchymal cell apoptotic process involved in metanephros development+++GO:1900215///negative regulation of apoptotic process involved in metanephric collecting duct development+++GO:1900218///negative regulation of apoptotic process involved in metanephric nephron tubule development+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000594///positive regulation of metanephric DCT cell differentiation+++GO:2000597///positive regulation of optic nerve formation" 18505 18505 'Pax3' mRNA 56 51 36 0.78 0.72 0.53 0.77 0.81 0.79 0.676666667 0.79 62 65 62 47.66666667 63 0.299140156 0.39745915 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001224///RNA polymerase II transcription cofactor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0001843///neural tube closure+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0014807///regulation of somitogenesis+++GO:0016477///cell migration+++GO:0021527///spinal cord association neuron differentiation+++GO:0021915///neural tube development+++GO:0035914///skeletal muscle cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048066///developmental pigmentation+++GO:0048663///neuron fate commitment+++GO:0048856///anatomical structure development+++GO:0055007///cardiac muscle cell differentiation+++GO:0060538///skeletal muscle organ development+++GO:0060594///mammary gland specification" 18507 18507 'Pax5' mRNA 7 1 0 0.04 0.01 0 0 0.01 0 0.016666667 0.003333333 0 1 0 2.666666667 0.333333333 0.305898676 -2.879557062 05202///Transcriptional misregulation in cancer GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0007568///aging+++GO:0009887///animal organ morphogenesis+++GO:0021670///lateral ventricle development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030534///adult behavior+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048856///anatomical structure development+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0071542///dopaminergic neuron differentiation" 18508 18508 'Pax6' mRNA 1.24 3.68 7.19 0.02 0.06 0.12 0.03 0.03 0.09 0.066666667 0.05 2.22 2.12 6.6 4.036666667 3.646666667 0.922565179 -0.174096146 04550///Signaling pathways regulating pluripotency of stem cells+++04950///Maturity onset diabetes of the young GO:0000785///chromatin+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035035///histone acetyltransferase binding+++GO:0043565///sequence-specific DNA binding+++GO:0070410///co-SMAD binding+++GO:0070412///R-SMAD binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000132///establishment of mitotic spindle orientation+++GO:0001568///blood vessel development+++GO:0001709///cell fate determination+++GO:0001755///neural crest cell migration+++GO:0001764///neuron migration+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002064///epithelial cell development+++GO:0002088///lens development in camera-type eye+++GO:0003002///regionalization+++GO:0003309///type B pancreatic cell differentiation+++GO:0003310///pancreatic A cell differentiation+++GO:0003322///pancreatic A cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007435///salivary gland morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009786///regulation of asymmetric cell division+++GO:0009950///dorsal/ventral axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0010975///regulation of neuron projection development+++GO:0021517///ventral spinal cord development+++GO:0021543///pallium development+++GO:0021593///rhombomere morphogenesis+++GO:0021772///olfactory bulb development+++GO:0021778///oligodendrocyte cell fate specification+++GO:0021796///cerebral cortex regionalization+++GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0021905///forebrain-midbrain boundary formation+++GO:0021978///telencephalon regionalization+++GO:0021983///pituitary gland development+++GO:0021986///habenula development+++GO:0022027///interkinetic nuclear migration+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030334///regulation of cell migration+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0032808///lacrimal gland development+++GO:0033365///protein localization to organelle+++GO:0042462///eye photoreceptor cell development+++GO:0042593///glucose homeostasis+++GO:0042660///positive regulation of cell fate specification+++GO:0043010///camera-type eye development+++GO:0045165///cell fate commitment+++GO:0045664///regulation of neuron differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048505///regulation of timing of cell differentiation+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048708///astrocyte differentiation+++GO:0048856///anatomical structure development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:0061034///olfactory bulb mitral cell layer development+++GO:0061072///iris morphogenesis+++GO:0061303///cornea development in camera-type eye+++GO:0061351///neural precursor cell proliferation+++GO:0070094///positive regulation of glucagon secretion+++GO:0098598///learned vocalization behavior or vocal learning+++GO:0120008///positive regulation of glutamatergic neuron differentiation+++GO:1901142///insulin metabolic process+++GO:1904798///positive regulation of core promoter binding+++GO:1904937///sensory neuron migration+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2001224///positive regulation of neuron migration" 18510 18510 'Pax8' mRNA 10 15 12 0.22 0.32 0.28 0.04 0.02 0.08 0.273333333 0.046666667 2 1 4 12.33333333 2.333333333 0.021534822 -2.413273244 04918///Thyroid hormone synthesis+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05216///Thyroid cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0003281///ventricular septum development+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006790///sulfur compound metabolic process+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0009887///animal organ morphogenesis+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0030154///cell differentiation+++GO:0030878///thyroid gland development+++GO:0039003///pronephric field specification+++GO:0042472///inner ear morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048793///pronephros development+++GO:0048856///anatomical structure development+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0071599///otic vesicle development+++GO:0072050///S-shaped body morphogenesis+++GO:0072073///kidney epithelium development+++GO:0072108///positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0072164///mesonephric tubule development+++GO:0072207///metanephric epithelium development+++GO:0072221///metanephric distal convoluted tubule development+++GO:0072278///metanephric comma-shaped body morphogenesis+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0072289///metanephric nephron tubule formation+++GO:0072305///negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1900212///negative regulation of mesenchymal cell apoptotic process involved in metanephros development+++GO:1900215///negative regulation of apoptotic process involved in metanephric collecting duct development+++GO:1900218///negative regulation of apoptotic process involved in metanephric nephron tubule development+++GO:2000594///positive regulation of metanephric DCT cell differentiation+++GO:2000611///positive regulation of thyroid hormone generation+++GO:2000612///regulation of thyroid-stimulating hormone secretion" 18511 18511 'Pax9' mRNA 7.99 4.95 5.96 0.1 0.06 0.08 0.07 0.09 0.04 0.08 0.066666667 6.93 7.94 4 6.3 6.29 0.958024763 0.076182451 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0009887///animal organ morphogenesis+++GO:0042476///odontogenesis+++GO:0042481///regulation of odontogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development+++GO:0060325///face morphogenesis+++GO:0071363///cellular response to growth factor stimulus" 18514 18514 'Pbx1' mRNA 1688 1687 1666 12.95 12.74 13.59 6.89 5.46 5.73 13.09333333 6.026666667 1015 784 826 1680.333333 875 4.30E-24 -0.956010245 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001654///eye development+++GO:0001655///urogenital system development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001779///natural killer cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006694///steroid biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007548///sex differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0009954///proximal/distal pattern formation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0030154///cell differentiation+++GO:0030278///regulation of ossification+++GO:0030325///adrenal gland development+++GO:0030326///embryonic limb morphogenesis+++GO:0035162///embryonic hemopoiesis+++GO:0042127///regulation of cell proliferation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048568///embryonic organ development+++GO:0048666///neuron development+++GO:0048706///embryonic skeletal system development" 18515 18515 'Pbx2' mRNA 146 138 88 2.61 2.42 1.67 2.58 2.21 2.48 2.233333333 2.423333333 166 139 155 124 153.3333333 0.248203341 0.301636919 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0009887///animal organ morphogenesis+++GO:0009954///proximal/distal pattern formation+++GO:0030326///embryonic limb morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048666///neuron development" 18516 18516 'Pbx3' mRNA 261 243 234 5.12 4.69 4.87 4.59 4.62 4.41 4.893333333 4.54 268 264 251 246 261 0.728867167 0.074249941 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0001654///eye development+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007585///respiratory gaseous exchange+++GO:0008344///adult locomotory behavior+++GO:0009887///animal organ morphogenesis+++GO:0021516///dorsal spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048666///neuron development" 18518 18518 'Igbp1' mRNA 552 571 531 21.45 21.88 21.89 23.44 21.08 20.52 21.74 21.68 693 608 587 551.3333333 629.3333333 0.146877221 0.178600756 04136///Autophagy - other+++04140///Autophagy - animal GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0044877///protein-containing complex binding+++GO:0051721///protein phosphatase 2A binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0009966///regulation of signal transduction+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0034612///response to tumor necrosis factor+++GO:0035303///regulation of dephosphorylation+++GO:0035306///positive regulation of dephosphorylation+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0042113///B cell activation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060632///regulation of microtubule-based movement+++GO:0070555///response to interleukin-1+++GO:2001234///negative regulation of apoptotic signaling pathway 18519 18519 'Kat2b' mRNA 753 677 608 9.84 8.8 8.44 10.31 10.36 10.65 9.026666667 10.44 899 884 897 679.3333333 893.3333333 1.60E-04 0.385739212 04330///Notch signaling pathway+++04919///Thyroid hormone signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000123///histone acetyltransferase complex+++GO:0000776///kinetochore+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031672///A band+++GO:0031674///I band+++GO:0032991///protein-containing complex+++GO:0042641///actomyosin "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0004145///diamine N-acetyltransferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0008134///transcription factor binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019901///protein kinase binding+++GO:0035035///histone acetyltransferase binding+++GO:0042826///histone deacetylase binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity" "GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006473///protein acetylation+++GO:0007049///cell cycle+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0010835///regulation of protein ADP-ribosylation+++GO:0010976///positive regulation of neuron projection development+++GO:0016573///histone acetylation+++GO:0018076///N-terminal peptidyl-lysine acetylation+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0018394///peptidyl-lysine acetylation+++GO:0032869///cellular response to insulin stimulus+++GO:0035563///positive regulation of chromatin binding+++GO:0043966///histone H3 acetylation+++GO:0043970///histone H3-K9 acetylation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046600///negative regulation of centriole replication+++GO:0048511///rhythmic process+++GO:0060173///limb development+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:2000233///negative regulation of rRNA processing+++GO:2000617///positive regulation of histone H3-K9 acetylation" 18521 18521 'Pcbp2' mRNA 1408.82 1351.83 1231.33 43.44 40.89 42.22 46.69 44.74 46.83 42.18333333 46.08666667 1722.76 1592.45 1656.41 1330.66 1657.206667 7.39E-05 0.306206546 04216///Ferroptosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:1990829///C-rich single-stranded DNA binding GO:0002376///immune system process+++GO:0010468///regulation of gene expression+++GO:0039694///viral RNA genome replication+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050687///negative regulation of defense response to virus+++GO:0051252///regulation of RNA metabolic process+++GO:0051607///defense response to virus+++GO:0075522///IRES-dependent viral translational initiation 18526 18526 'Pcdh10' mRNA 15 12 12 0.1 0.08 0.11 0.13 0.09 0.11 0.096666667 0.11 18 12 13 13 14.33333333 0.879031168 0.126940488 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 18530 18530 'Pcdh8' mRNA 14 7 5 0.2 0.1 0.08 0.01 0 0 0.126666667 0.003333333 1 0 0 8.666666667 0.333333333 0.007321914 -4.596497531 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005509///calcium ion binding GO:0001756///somitogenesis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007268///chemical synaptic transmission+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0050804///modulation of chemical synaptic transmission+++GO:0099179///regulation of synaptic membrane adhesion 18536 18536 'Pcm1' mRNA 2501 2493 2257 15.44 15.11 14.78 9.38 8.22 8.54 15.11 8.713333333 1753 1498 1545 2417 1598.666667 5.59E-17 -0.607918401 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045177///apical part of cell GO:0005515///protein binding GO:0001764///neuron migration+++GO:0007098///centrosome cycle+++GO:0022027///interkinetic nuclear migration+++GO:0030030///cell projection organization+++GO:0031122///cytoplasmic microtubule organization+++GO:0033365///protein localization to organelle+++GO:0034453///microtubule anchoring+++GO:0034454///microtubule anchoring at centrosome+++GO:0035176///social behavior+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0050768///negative regulation of neurogenesis+++GO:0060271///cilium assembly+++GO:0071539///protein localization to centrosome+++GO:0090316///positive regulation of intracellular protein transport+++GO:0097150///neuronal stem cell population maintenance+++GO:1905515///non-motile cilium assembly 18537 18537 'Pcmt1' mRNA 2256 2309 2289 42.9 43.32 45.56 39.57 40.78 36.9 43.92666667 39.08333333 2366 2359 2113 2284.666667 2279.333333 0.869907916 -0.016107257 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031526///brush border membrane+++GO:0043005///neuron projection+++GO:0043204///perikaryon GO:0004719///protein-L-isoaspartate (D-aspartate) O-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity GO:0006464///cellular protein modification process+++GO:0006479///protein methylation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0032259///methylation+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0046500///S-adenosylmethionine metabolic process 18538 18538 'Pcna' mRNA 663 674 609 32.02 32.13 31.2 68.24 62.02 67.78 31.78333333 66.01333333 1622 1438 1558 648.6666667 1539.333333 1.95E-48 1.235493594 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair+++04110///Cell cycle+++04530///Tight junction+++05161///Hepatitis B GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005813///centrosome+++GO:0016604///nuclear body+++GO:0043596///nuclear replication fork+++GO:0043626///PCNA complex+++GO:0070557///PCNA-p21 complex GO:0000701///purine-specific mismatch base pair DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0030331///estrogen receptor binding+++GO:0030337///DNA polymerase processivity factor activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0032139///dinucleotide insertion or deletion binding+++GO:0032405///MutLalpha complex binding+++GO:0035035///histone acetyltransferase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0070182///DNA polymerase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006272///leading strand elongation+++GO:0006275///regulation of DNA replication+++GO:0006281///DNA repair+++GO:0006287///base-excision repair, gap-filling+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007507///heart development+++GO:0019985///translesion synthesis+++GO:0030855///epithelial cell differentiation+++GO:0031297///replication fork processing+++GO:0032077///positive regulation of deoxyribonuclease activity+++GO:0032355///response to estradiol+++GO:0033993///response to lipid+++GO:0034644///cellular response to UV+++GO:0044849///estrous cycle+++GO:0045739///positive regulation of DNA repair+++GO:0045740///positive regulation of DNA replication+++GO:0046686///response to cadmium ion+++GO:0050790///regulation of catalytic activity+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071548///response to dexamethasone+++GO:0097421///liver regeneration+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity+++GO:1902065///response to L-glutamate+++GO:1902990///mitotic telomere maintenance via semi-conservative replication" 18541 18541 'Pcnt' mRNA 676 667 669 3.64 3.48 3.78 3.15 2.94 3.1 3.633333333 3.063333333 673 620 649 670.6666667 647.3333333 0.636398589 -0.063982001 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005801///cis-Golgi network+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0045171///intercellular bridge GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0060090///molecular adaptor activity GO:0000226///microtubule cytoskeleton organization+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001822///kidney development+++GO:0001944///vasculature development+++GO:0007051///spindle organization+++GO:0007052///mitotic spindle organization+++GO:0007165///signal transduction+++GO:0021696///cerebellar cortex morphogenesis+++GO:0021772///olfactory bulb development+++GO:0035050///embryonic heart tube development+++GO:0035108///limb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0048854///brain morphogenesis+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:0061351///neural precursor cell proliferation+++GO:0090316///positive regulation of intracellular protein transport+++GO:1990403///embryonic brain development 18542 18542 'Pcolce' mRNA 1962 1965 2000 75.04 74.12 81.16 257.7 262.52 257.04 76.77333333 259.0866667 7740 7694 7469 1975.666667 7634.333333 2.57E-220 1.937323739 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0016504///peptidase activator activity GO:0006508///proteolysis+++GO:0010952///positive regulation of peptidase activity+++GO:1990830///cellular response to leukemia inhibitory factor 18545 18545 'Pcp2' mRNA 1.02 0 3.07 0.2 0 0.45 0.12 0.52 0 0.216666667 0.213333333 1.01 3 0 1.363333333 1.336666667 0.995389082 -0.044238716 GO:0043025///neuronal cell body GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030695///GTPase regulator activity GO:0016056///rhodopsin mediated signaling pathway 18546 18546 'Pcp4' mRNA 2211 2176 2314 255.73 250.3 284.08 40.21 41.98 44.75 263.37 42.31333333 397 403 426 2233.666667 408.6666667 1.51E-156 -2.464244972 GO:0005737///cytoplasm+++GO:0005883///neurofilament+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection GO:0003723///RNA binding+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding GO:0006469///negative regulation of protein kinase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0033603///positive regulation of dopamine secretion+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0099004///calmodulin dependent kinase signaling pathway 18548 18548 'Pcsk1' mRNA 85 81 78 0.91 0.85 0.89 0.16 0.09 0.07 0.883333333 0.106666667 17 9 7 81.33333333 11 8.73E-12 -2.901536557 GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005791///rough endoplasmic reticulum+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0034774///secretory granule lumen+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0048471///perinuclear region of cytoplasm GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0016540///protein autoprocessing+++GO:0043043///peptide biosynthetic process+++GO:0050714///positive regulation of protein secretion 18549 18549 'Pcsk2' mRNA 5 14 2 0.06 0.16 0.02 0.02 0.01 0.08 0.08 0.036666667 2 1 8 7 3.666666667 0.537270548 -0.91567442 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0034774///secretory granule lumen+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007399///nervous system development+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0016540///protein autoprocessing+++GO:0030070///insulin processing+++GO:0034230///enkephalin processing+++GO:0034231///islet amyloid polypeptide processing 18550 18550 'Furin' mRNA 525 504 461 6.73 6.39 6.28 9.94 9.17 10.1 6.466666667 9.736666667 886 802 873 496.6666667 853.6666667 3.43E-14 0.770531585 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0012510///trans-Golgi network transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0031985///Golgi cisterna+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0048406///nerve growth factor binding GO:0001825///blastocyst formation+++GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0009966///regulation of signal transduction+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0019058///viral life cycle+++GO:0030335///positive regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031638///zymogen activation+++GO:0032374///regulation of cholesterol transport+++GO:0032804///negative regulation of low-density lipoprotein particle receptor catabolic process+++GO:0032902///nerve growth factor production+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0032940///secretion by cell+++GO:0042176///regulation of protein catabolic process+++GO:0043043///peptide biosynthetic process+++GO:0052548///regulation of endopeptidase activity+++GO:0090472///dibasic protein processing+++GO:0097341///zymogen inhibition+++GO:1901394///positive regulation of transforming growth factor beta1 activation 18551 18551 'Pcsk4' mRNA 304 322 254 6.58 6.82 5.88 2.12 1.84 1.68 6.426666667 1.88 113 94 83 293.3333333 96.66666667 1.43E-17 -1.610751348 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030173///integral component of Golgi membrane+++GO:0031410///cytoplasmic vesicle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007339///binding of sperm to zona pellucida+++GO:0007340///acrosome reaction+++GO:0009566///fertilization+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0022414///reproductive process+++GO:0048240///sperm capacitation 18552 18552 'Pcsk5' mRNA 2069 2061 1668 24.15 23.81 22.1 3.39 2.48 2.94 23.35333333 2.936666667 308 219 270 1932.666667 265.6666667 7.83E-153 -2.872517849 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0030173///integral component of Golgi membrane+++GO:0043204///perikaryon+++GO:1990635///proximal dendrite GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0007566///embryo implantation+++GO:0009952///anterior/posterior pattern specification+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0019058///viral life cycle+++GO:0030323///respiratory tube development+++GO:0033625///positive regulation of integrin activation+++GO:0035108///limb morphogenesis+++GO:0043043///peptide biosynthetic process+++GO:0048566///embryonic digestive tract development+++GO:0048706///embryonic skeletal system development+++GO:0060976///coronary vasculature development+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1905609///positive regulation of smooth muscle cell-matrix adhesion+++GO:2001046///positive regulation of integrin-mediated signaling pathway 18553 18553 'Pcsk6' mRNA 583 580 550 7.31 7.14 7.31 2.39 2.14 2.5 7.253333333 2.343333333 219 192 222 571 211 8.38E-29 -1.448178838 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0048406///nerve growth factor binding "GO:0006508///proteolysis+++GO:0007354///zygotic determination of anterior/posterior axis, embryo+++GO:0007368///determination of left/right symmetry+++GO:0009100///glycoprotein metabolic process+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0032902///nerve growth factor production+++GO:0032940///secretion by cell" 18554 18554 'Pcsk7' mRNA 576.79 600.73 646.96 6.64 6.9 8.23 7.65 7.69 7.77 7.256666667 7.703333333 737.15 683.19 727.77 608.16 716.0366667 0.066909539 0.221930757 GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016485///protein processing 18555 18555 'Cdk16' mRNA 3681 3734 972 64.65 64.52 18.03 20.86 40.97 38.26 49.06666667 33.36333333 1370 2622 2431 2795.666667 2141 0.665161926 -0.364085552 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006887///exocytosis+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0030252///growth hormone secretion+++GO:0031175///neuron projection development+++GO:0051726///regulation of cell cycle+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus 18557 18557 'Cdk18' mRNA 178 165 163 3.21 2.93 3.11 4.27 4.2 4.35 3.083333333 4.273333333 273 262 269 168.6666667 268 1.10E-04 0.656428114 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle 18559 18559 'Pctp' mRNA 173 154 193 3.37 2.94 3.98 3.73 3.85 3.83 3.43 3.803333333 221 222 218 173.3333333 220.3333333 0.106727903 0.330145581 GO:0005737///cytoplasm GO:0008289///lipid binding+++GO:0008525///phosphatidylcholine transporter activity+++GO:0031210///phosphatidylcholine binding GO:0006869///lipid transport+++GO:0008203///cholesterol metabolic process+++GO:0015914///phospholipid transport+++GO:0120163///negative regulation of cold-induced thermogenesis 18563 18563 'Pcx' mRNA 1950 2045 2003 25.33 26.13 27.6 11.7 10.8 11.02 26.35333333 11.17333333 1037 934 945 1999.333333 972 1.40E-40 -1.05383517 00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004736///pyruvate carboxylase activity+++GO:0005524///ATP binding+++GO:0009374///biotin binding+++GO:0016874///ligase activity+++GO:0031406///carboxylic acid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006090///pyruvate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006107///oxaloacetate metabolic process+++GO:0006629///lipid metabolic process+++GO:0008152///metabolic process+++GO:0010629///negative regulation of gene expression+++GO:0019074///viral RNA genome packaging+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0044794///positive regulation by host of viral process+++GO:0071073///positive regulation of phospholipid biosynthetic process 18566 18566 'Pdcd1' mRNA 1 5 4 0.03 0.15 0.13 0.64 0.42 0.69 0.103333333 0.583333333 25 16 26 3.333333333 22.33333333 8.62E-04 2.728057774 04514///Cell adhesion molecules+++04660///T cell receptor signaling pathway+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002644///negative regulation of tolerance induction+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0050776///regulation of immune response+++GO:0050777///negative regulation of immune response+++GO:0070234///positive regulation of T cell apoptotic process 18567 18567 'Pdcd2' mRNA 375.81 387.22 362.14 17.47 18.48 17.7 19.2 19.76 21.83 17.88333333 20.26333333 455.75 439.6 486.03 375.0566667 460.46 0.033047911 0.284842132 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0012501///programmed cell death+++GO:0043065///positive regulation of apoptotic process+++GO:1901532///regulation of hematopoietic progenitor cell differentiation+++GO:1902035///positive regulation of hematopoietic stem cell proliferation 18569 18569 'Pdcd4' mRNA 1788 1529.11 1976.65 38.13 32.33 46.67 27.33 28.33 27.46 39.04333333 27.70666667 1423.34 1426.26 1380.41 1764.586667 1410.003333 0.002316054 -0.34141092 05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0006915///apoptotic process+++GO:0007569///cell aging+++GO:0030509///BMP signaling pathway+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050729///positive regulation of inflammatory response+++GO:0051246///regulation of protein metabolic process+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0071222///cellular response to lipopolysaccharide+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904761///negative regulation of myofibroblast differentiation+++GO:1905064///negative regulation of vascular smooth muscle cell differentiation+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:2000353///positive regulation of endothelial cell apoptotic process" 18570 18570 'Pdcd6' mRNA 2254 2348 2351 113.49 115.36 125.05 121.74 120.5 121.25 117.9666667 121.1633333 2866 2798 2769 2317.666667 2811 2.02E-04 0.26532743 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site "GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0000287///magnesium ion binding+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043495///protein membrane anchor+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006486///protein glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0010595///positive regulation of endothelial cell migration+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development+++GO:0016567///protein ubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0034605///cellular response to heat+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0048208///COPII vesicle coating+++GO:0051592///response to calcium ion+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0097502///mannosylation+++GO:1902527///positive regulation of protein monoubiquitination 18571 18571 'Pdcd6ip' mRNA 2714 2630 2655 24.2 23.06 25.12 32.76 32.79 33.24 24.12666667 32.93 4227 4135 4156 2666.333333 4172.666667 2.18E-24 0.633538517 04144///Endocytosis GO:0001772///immunological synapse+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0042470///melanosome+++GO:0042641///actomyosin+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0070971///endoplasmic reticulum exit site+++GO:0090543///Flemming body GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0031871///proteinase activated receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046983///protein dimerization activity+++GO:0048306///calcium-dependent protein binding GO:0000281///mitotic cytokinesis+++GO:0000915///actomyosin contractile ring assembly+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0039702///viral budding via host ESCRT complex+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0046755///viral budding+++GO:0051260///protein homooligomerization+++GO:0051301///cell division+++GO:0061952///midbody abscission+++GO:0070830///bicellular tight junction assembly+++GO:0090559///regulation of membrane permeability+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:1903543///positive regulation of exosomal secretion+++GO:1903551///regulation of extracellular exosome assembly+++GO:1903553///positive regulation of extracellular exosome assembly 18572 18572 'Pdcd11' mRNA 425 480 487 3.73 4.14 4.53 3.61 3.57 2.85 4.133333333 3.343333333 474 457 362 464 431 0.490407417 -0.120997013 GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032040///small-subunit processome GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008134///transcription factor binding GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0051384///response to glucocorticoid+++GO:0070234///positive regulation of T cell apoptotic process+++GO:2001235///positive regulation of apoptotic signaling pathway 18573 18573 'Pde1a' mRNA 98 130 135 1.73 2.54 2.44 1.96 1.79 2.06 2.236666667 1.936666667 122 116 127 121 121.6666667 0.987839851 -0.007501802 00230///Purine metabolism+++04020///Calcium signaling pathway+++04740///Olfactory transduction+++04742///Taste transduction+++04924///Renin secretion+++05032///Morphine addiction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004117///calmodulin-dependent cyclic-nucleotide phosphodiesterase activity+++GO:0005516///calmodulin binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0048101///calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0034391///regulation of smooth muscle cell apoptotic process+++GO:0046069///cGMP catabolic process+++GO:0048660///regulation of smooth muscle cell proliferation 18574 18574 'Pde1b' mRNA 165 131 145 3.12 2.42 2.92 3.24 3.33 3.68 2.82 3.416666667 204 198 215 147 205.6666667 0.019695006 0.472038408 00230///Purine metabolism+++04020///Calcium signaling pathway+++04740///Olfactory transduction+++04742///Taste transduction+++04924///Renin secretion+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0043025///neuronal cell body "GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004117///calmodulin-dependent cyclic-nucleotide phosphodiesterase activity+++GO:0005516///calmodulin binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0048101///calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity" GO:0001505///regulation of neurotransmitter levels+++GO:0001975///response to amphetamine+++GO:0007165///signal transduction+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0030224///monocyte differentiation+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0042053///regulation of dopamine metabolic process+++GO:0042428///serotonin metabolic process+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus 18575 18575 'Pde1c' mRNA 288 275 311 3.11 2.85 3.78 1.41 1.48 1.65 3.246666667 1.513333333 174 167 190 291.3333333 177 2.20E-05 -0.733749175 00230///Purine metabolism+++04020///Calcium signaling pathway+++04740///Olfactory transduction+++04742///Taste transduction+++04924///Renin secretion+++05032///Morphine addiction GO:0005764///lysosome+++GO:0005929///cilium+++GO:0043025///neuronal cell body "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004117///calmodulin-dependent cyclic-nucleotide phosphodiesterase activity+++GO:0005516///calmodulin binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030552///cAMP binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0048101///calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0007608///sensory perception of smell+++GO:0051592///response to calcium ion+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 18576 18576 'Pde3b' mRNA 21 34 28 0.21 0.34 0.3 0.51 0.83 0.61 0.283333333 0.65 58 93 68 27.66666667 73 3.15E-04 1.392473769 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04371///Apelin signaling pathway+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++05032///Morphine addiction GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032045///guanyl-nucleotide exchange factor complex "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0043422///protein kinase B binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding" GO:0001525///angiogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0016525///negative regulation of angiogenesis+++GO:0031018///endocrine pancreas development+++GO:0032869///cellular response to insulin stimulus+++GO:0042593///glucose homeostasis+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0050796///regulation of insulin secretion+++GO:0050995///negative regulation of lipid catabolic process+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 18577 18577 'Pde4a' mRNA 550 560 489 6.86 6.92 6.47 5.26 5.18 5.52 6.75 5.32 493 467 500 533 486.6666667 0.282896527 -0.141136355 "00230///Purine metabolism+++04024///cAMP signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05032///Morphine addiction" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030552///cAMP binding+++GO:0046872///metal ion binding" GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0007608///sensory perception of smell+++GO:0010738///regulation of protein kinase A signaling+++GO:0035690///cellular response to drug+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0050804///modulation of chemical synaptic transmission+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0106070///regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 18578 18578 'Pde4b' mRNA 3775.47 3925.45 3603.09 43.67 44.66 44.8 24.14 24.43 23.17 44.37666667 23.91333333 2546.51 2396.64 2268.78 3768.003333 2403.976667 6.79E-26 -0.660140435 "00230///Purine metabolism+++04024///cAMP signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05032///Morphine addiction" GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005891///voltage-gated calcium channel complex+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0043197///dendritic spine+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0071944///cell periphery "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030552///cAMP binding+++GO:0043015///gamma-tubulin binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding" GO:0001780///neutrophil homeostasis+++GO:0006198///cAMP catabolic process+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0009408///response to heat+++GO:0030593///neutrophil chemotaxis+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0035690///cellular response to drug+++GO:0050852///T cell receptor signaling pathway+++GO:0050900///leukocyte migration+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071872///cellular response to epinephrine stimulus+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0140199///negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901898///negative regulation of relaxation of cardiac muscle 18582 18582 'Pde6d' mRNA 2133 2146 2074 96.15 99.18 100.24 54.35 56.08 54.32 98.52333333 54.91666667 1348.96 1446 1326 2117.666667 1373.653333 8.71E-17 -0.63602054 00230///Purine metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection "GO:0005095///GTPase inhibitor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0043086///negative regulation of catalytic activity+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus 18583 18583 'Pde7a' mRNA 260.97 249.06 230.05 2.66 2.69 2.43 2.46 1.87 2.8 2.593333333 2.376666667 279.03 209.07 292.11 246.6933333 260.07 0.781781401 0.065797926 00230///Purine metabolism+++05032///Morphine addiction "GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0019933///cAMP-mediated signaling 18584 18584 'Pde8a' mRNA 76 54 53 0.99 0.69 0.74 1.89 1.55 1.78 0.806666667 1.74 166 134 152 61 150.6666667 3.78E-07 1.293397043 00230///Purine metabolism+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++05032///Morphine addiction "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" "GO:0001934///positive regulation of protein phosphorylation+++GO:0006198///cAMP catabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0060548///negative regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death" 18585 18585 'Pde9a' mRNA 36 50 43 1.04 1.44 1.35 1.76 1.28 1.83 1.276666667 1.623333333 71 53 71 43 65 0.117686765 0.582893473 00230///Purine metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0019934///cGMP-mediated signaling+++GO:0046068///cGMP metabolic process+++GO:0046069///cGMP catabolic process 18587 18587 'Pde6b' mRNA 0 5 3 0 0.1 0.06 0.02 0 0 0.053333333 0.006666667 1 0 0 2.666666667 0.333333333 0.285438192 -2.907107338 00230///Purine metabolism+++04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042622///photoreceptor outer segment membrane "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0009583///detection of light stimulus+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:1990009///retinal cell apoptotic process 18588 18588 'Pde6g' mRNA 11 1 8 0.78 0.07 0.6 0.37 0.83 0.14 0.483333333 0.446666667 6 13 3 6.666666667 7.333333333 0.931553089 0.120589921 00230///Purine metabolism+++04744///Phototransduction GO:0005886///plasma membrane+++GO:0042622///photoreceptor outer segment membrane "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0030507///spectrin binding+++GO:0030553///cGMP binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0000187///activation of MAPK activity+++GO:0007601///visual perception+++GO:0043410///positive regulation of MAPK cascade+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus 18590 18590 'Pdgfa' mRNA 1065 1032 838 28.21 27.27 23.6 24.03 25.6 26.94 26.36 25.52333333 1018 1038 1103 978.3333333 1053 0.392991902 0.098859026 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05231///Choline metabolism in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0016020///membrane GO:0005161///platelet-derived growth factor receptor binding+++GO:0005518///collagen binding+++GO:0008083///growth factor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0048407///platelet-derived growth factor binding+++GO:0070851///growth factor receptor binding GO:0001525///angiogenesis+++GO:0001942///hair follicle development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009887///animal organ morphogenesis+++GO:0010512///negative regulation of phosphatidylinositol biosynthetic process+++GO:0010544///negative regulation of platelet activation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014910///regulation of smooth muscle cell migration+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0035793///positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043588///skin development+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048286///lung alveolus development+++GO:0048565///digestive tract development+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050919///negative chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060348///bone development+++GO:0060683///regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072124///regulation of glomerular mesangial cell proliferation+++GO:1990401///embryonic lung development+++GO:2000278///regulation of DNA biosynthetic process 18591 18591 'Pdgfb' mRNA 35 32 46 0.87 0.78 1.29 3.19 2.96 2.96 0.98 3.036666667 142 126 129 37.66666667 132.3333333 3.36E-10 1.794458461 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05231///Choline metabolism in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004558///alpha-1,4-glucosidase activity+++GO:0004564///beta-fructofuranosidase activity+++GO:0004574///oligo-1,6-glucosidase activity+++GO:0005102///signaling receptor binding+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005518///collagen binding+++GO:0008083///growth factor activity+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0048407///platelet-derived growth factor binding+++GO:0070851///growth factor receptor binding" "GO:0001568///blood vessel development+++GO:0001892///embryonic placenta development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002548///monocyte chemotaxis+++GO:0003104///positive regulation of glomerular filtration+++GO:0005975///carbohydrate metabolic process+++GO:0006468///protein phosphorylation+++GO:0006929///substrate-dependent cell migration+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007416///synapse assembly+++GO:0007507///heart development+++GO:0008152///metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0010512///negative regulation of phosphatidylinositol biosynthetic process+++GO:0010544///negative regulation of platelet activation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016322///neuron remodeling+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021782///glial cell development+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030097///hemopoiesis+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0032148///activation of protein kinase B activity+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035655///interleukin-18-mediated signaling pathway+++GO:0035793///positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway+++GO:0038001///paracrine signaling+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0042310///vasoconstriction+++GO:0042462///eye photoreceptor cell development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045740///positive regulation of DNA replication+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0045977///positive regulation of mitotic cell cycle, embryonic+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048514///blood vessel morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0050921///positive regulation of chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0060041///retina development in camera-type eye+++GO:0060326///cell chemotaxis+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061298///retina vasculature development in camera-type eye+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070528///protein kinase C signaling+++GO:0071363///cellular response to growth factor stimulus+++GO:0071506///cellular response to mycophenolic acid+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0072255///metanephric glomerular mesangial cell development+++GO:0072262///metanephric glomerular mesangial cell proliferation involved in metanephros development+++GO:0072264///metanephric glomerular endothelium development+++GO:0072593///reactive oxygen species metabolic process+++GO:0090280///positive regulation of calcium ion import+++GO:1900127///positive regulation of hyaluronan biosynthetic process+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1904899///positive regulation of hepatic stellate cell proliferation+++GO:1905064///negative regulation of vascular smooth muscle cell differentiation+++GO:1905176///positive regulation of vascular smooth muscle cell dedifferentiation+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000491///positive regulation of hepatic stellate cell activation+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000591///positive regulation of metanephric mesenchymal cell migration" 18595 18595 'Pdgfra' mRNA 1694 1804 1817 13.98 14.63 15.94 21.7 20.47 21.12 14.85 21.09666667 3051 2800 2866 1771.666667 2905.666667 9.22E-22 0.699835852 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031226///intrinsic component of plasma membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005018///platelet-derived growth factor alpha-receptor activity+++GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0038085///vascular endothelial growth factor binding+++GO:0042803///protein homodimerization activity+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding+++GO:0048407///platelet-derived growth factor binding GO:0001553///luteinization+++GO:0001701///in utero embryonic development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006468///protein phosphorylation+++GO:0006935///chemotaxis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0008210///estrogen metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008585///female gonad development+++GO:0009653///anatomical structure morphogenesis+++GO:0009887///animal organ morphogenesis+++GO:0010544///negative regulation of platelet activation+++GO:0010863///positive regulation of phospholipase C activity+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030198///extracellular matrix organization+++GO:0030324///lung development+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0030539///male genitalia development+++GO:0033327///Leydig cell differentiation+++GO:0033674///positive regulation of kinase activity+++GO:0034614///cellular response to reactive oxygen species+++GO:0035790///platelet-derived growth factor receptor-alpha signaling pathway+++GO:0038091///positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway+++GO:0042060///wound healing+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050872///white fat cell differentiation+++GO:0050920///regulation of chemotaxis+++GO:0055003///cardiac myofibril assembly+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0060326///cell chemotaxis+++GO:0060437///lung growth+++GO:0061047///positive regulation of branching involved in lung morphogenesis+++GO:0061298///retina vasculature development in camera-type eye+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070527///platelet aggregation+++GO:0071230///cellular response to amino acid stimulus+++GO:0072277///metanephric glomerular capillary formation+++GO:2000739///regulation of mesenchymal stem cell differentiation 18596 18596 'Pdgfrb' mRNA 1183 1329 1383 11.73 13 14.59 18.66 17.48 16.88 13.10666667 17.67333333 2157 1985 1896 1298.333333 2012.666667 1.72E-11 0.617072486 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043202///lysosomal lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005017///platelet-derived growth factor-activated receptor activity+++GO:0005019///platelet-derived growth factor beta-receptor activity+++GO:0005102///signaling receptor binding+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0038085///vascular endothelial growth factor binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0048407///platelet-derived growth factor binding GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001894///tissue homeostasis+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006807///nitrogen compound metabolic process+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009636///response to toxic substance+++GO:0010863///positive regulation of phospholipase C activity+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014070///response to organic cyclic compound+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030097///hemopoiesis+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0032355///response to estradiol+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0032526///response to retinoic acid+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033674///positive regulation of kinase activity+++GO:0033993///response to lipid+++GO:0034405///response to fluid shear stress+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035441///cell migration involved in vasculogenesis+++GO:0035556///intracellular signal transduction+++GO:0035789///metanephric mesenchymal cell migration+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0035793///positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway+++GO:0035909///aorta morphogenesis+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0038091///positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway+++GO:0042060///wound healing+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0043627///response to estrogen+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046777///protein autophosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048568///embryonic organ development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0048839///inner ear development+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050921///positive regulation of chemotaxis+++GO:0055003///cardiac myofibril assembly+++GO:0055093///response to hyperoxia+++GO:0060326///cell chemotaxis+++GO:0060437///lung growth+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0060981///cell migration involved in coronary angiogenesis+++GO:0061298///retina vasculature development in camera-type eye+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071670///smooth muscle cell chemotaxis+++GO:0072075///metanephric mesenchyme development+++GO:0072223///metanephric glomerular mesangium development+++GO:0072262///metanephric glomerular mesangial cell proliferation involved in metanephros development+++GO:0072275///metanephric glomerulus morphogenesis+++GO:0072277///metanephric glomerular capillary formation+++GO:0072278///metanephric comma-shaped body morphogenesis+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0090280///positive regulation of calcium ion import+++GO:0097178///ruffle assembly+++GO:0106096///response to ceramide+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000491///positive regulation of hepatic stellate cell activation+++GO:2000573///positive regulation of DNA biosynthetic process 18597 18597 'Pdha1' mRNA 4109.9 4356.7 4264.57 79.36 82.79 87.35 72.5 70.07 66.06 83.16666667 69.54333333 4319.65 4077.4 3811.14 4243.723333 4069.396667 0.357799862 -0.073726168 00010///Glycolysis / Gluconeogenesis+++00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer+++05415///Diabetic cardiomyopathy GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045254///pyruvate dehydrogenase complex "GO:0004738///pyruvate dehydrogenase activity+++GO:0004739///pyruvate dehydrogenase (acetyl-transferring) activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0034604///pyruvate dehydrogenase (NAD+) activity" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006099///tricarboxylic acid cycle+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate 18599 18599 'Padi1' mRNA 393 462 311 5.67 6.55 4.76 4.4 4.35 4.58 5.66 4.443333333 351 339 354 388.6666667 348 0.341118175 -0.164810869 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004668///protein-arginine deiminase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0018101///protein citrullination+++GO:0036414///histone citrullination 18600 18600 'Padi2' mRNA 12477.3 12271.53 8281.68 140.36 135.73 98.82 55.51 56.01 56.75 124.97 56.09 5681.99 5601.09 5625.69 11010.17 5636.256667 2.41E-25 -0.968948582 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin GO:0004668///protein-arginine deiminase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0030331///estrogen receptor binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0010848///regulation of chromatin disassembly+++GO:0018101///protein citrullination+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0036413///histone H3-R26 citrullination+++GO:0036414///histone citrullination+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:1901624///negative regulation of lymphocyte chemotaxis+++GO:1990830///cellular response to leukemia inhibitory factor" 18602 18602 'Padi4' mRNA 235 195 219 4.94 4.03 4.88 4.94 5.46 5.19 4.616666667 5.196666667 270.23 292 275 216.3333333 279.0766667 0.046200137 0.35453004 04613///Neutrophil extracellular trap formation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0004668///protein-arginine deiminase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0034618///arginine binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0018101///protein citrullination+++GO:0019827///stem cell population maintenance+++GO:0036413///histone H3-R26 citrullination+++GO:0036414///histone citrullination+++GO:0045087///innate immune response 18604 18604 'Pdk2' mRNA 3554 3562 3367 88.22 87.12 88.66 58.47 58.33 56.67 88 57.82333333 2707 2638 2541 3494.333333 2628.666667 4.25E-12 -0.422178553 05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0045254///pyruvate dehydrogenase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0006468///protein phosphorylation+++GO:0006885///regulation of pH+++GO:0008286///insulin receptor signaling pathway+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate+++GO:0010565///regulation of cellular ketone metabolic process+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031670///cellular response to nutrient+++GO:0034614///cellular response to reactive oxygen species+++GO:0042593///glucose homeostasis+++GO:0050848///regulation of calcium-mediated signaling+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 18605 18605 'Enpp1' mRNA 502 550 466 3.92 4.22 3.86 6.99 7.12 6.87 4 6.993333333 1032 1023 983 506 1012.666667 1.47E-24 0.991245316 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00500///Starch and sucrose metabolism+++00740///Riboflavin metabolism+++00760///Nicotinate and nicotinamide metabolism+++00770///Pantothenate and CoA biosynthesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite GO:0003676///nucleic acid binding+++GO:0003824///catalytic activity+++GO:0004527///exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0005044///scavenger receptor activity+++GO:0005158///insulin receptor binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0030247///polysaccharide binding+++GO:0035529///NADH pyrophosphatase activity+++GO:0036218///dTTP diphosphatase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity GO:0006091///generation of precursor metabolites and energy+++GO:0006796///phosphate-containing compound metabolic process+++GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0030279///negative regulation of ossification+++GO:0030308///negative regulation of cell growth+++GO:0030318///melanocyte differentiation+++GO:0030500///regulation of bone mineralization+++GO:0030502///negative regulation of bone mineralization+++GO:0030505///inorganic diphosphate transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0030730///sequestering of triglyceride+++GO:0031214///biomineral tissue development+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0046034///ATP metabolic process+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046849///bone remodeling+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1990787///negative regulation of hh target transcription factor activity 18606 18606 'Enpp2' mRNA 3284 3458 3622 54.57 56.51 63.68 29.3 31.97 30.39 58.25333333 30.55333333 2034 2170 2043 3454.666667 2082.333333 5.61E-21 -0.744070734 00565///Ether lipid metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003824///catalytic activity+++GO:0004528///phosphodiesterase I activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0004622///lysophospholipase activity+++GO:0005044///scavenger receptor activity+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0030247///polysaccharide binding+++GO:0046872///metal ion binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity GO:0001953///negative regulation of cell-matrix adhesion+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006897///endocytosis+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0009395///phospholipid catabolic process+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016042///lipid catabolic process+++GO:0030149///sphingolipid catabolic process+++GO:0030334///regulation of cell migration+++GO:0034638///phosphatidylcholine catabolic process+++GO:0044849///estrous cycle+++GO:0045765///regulation of angiogenesis+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060326///cell chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:2000394///positive regulation of lamellipodium morphogenesis 18607 18607 'Pdpk1' mRNA 1027 1015 874 11.99 11.6 10.56 9.68 7.52 10.05 11.38333333 9.083333333 1050 790 970 972 936.6666667 0.643848614 -0.064649606 01524///Platinum drug resistance+++03320///PPAR signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++04931///Insulin resistance+++04960///Aldosterone-regulated sodium reabsorption+++05145///Toxoplasmosis+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05213///Endometrial cancer+++05215///Prostate cancer+++05223///Non-small cell lung cancer+++05231///Choline metabolism in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045254///pyruvate dehydrogenase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004676///3-phosphoinositide-dependent protein kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0044877///protein-containing complex binding GO:0003323///type B pancreatic cell development+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006972///hyperosmotic response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate+++GO:0010518///positive regulation of phospholipase activity+++GO:0010594///regulation of endothelial cell migration+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032148///activation of protein kinase B activity+++GO:0032869///cellular response to insulin stimulus+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043304///regulation of mast cell degranulation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0048041///focal adhesion assembly+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097411///hypoxia-inducible factor-1alpha signaling pathway+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000352///negative regulation of endothelial cell apoptotic process 18611 18611 'Pea15a' mRNA 5837 6214 6150 130.01 136.26 145.28 145.16 153.92 145.75 137.1833333 148.2766667 7496 7761 7287 6067 7514.666667 5.64E-06 0.296070395 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex GO:0005080///protein kinase C binding GO:0000165///MAPK cascade+++GO:0006915///apoptotic process+++GO:0008643///carbohydrate transport+++GO:0035556///intracellular signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043278///response to morphine+++GO:0046325///negative regulation of glucose import+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 18612 18612 'Etv4' mRNA 101 99 69 2.42 2.28 1.76 3.69 3.07 3.33 2.153333333 3.363333333 173 142 152 89.66666667 155.6666667 9.14E-04 0.788589524 05202///Transcriptional misregulation in cancer GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008045///motor neuron axon guidance+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:0060444///branching involved in mammary gland duct morphogenesis" 18613 18613 'Pecam1' mRNA 414 458 436 6.84 7.54 7.65 9.75 9.97 9.61 7.343333333 9.776666667 679 673 636 436 662.6666667 2.14E-07 0.591857589 04514///Cell adhesion molecules+++04670///Leukocyte transendothelial migration+++05144///Malaria+++05418///Fluid shear stress and atherosclerosis GO:0001726///ruffle+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030485///smooth muscle contractile fiber+++GO:0032991///protein-containing complex+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0071944///cell periphery GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002687///positive regulation of leukocyte migration+++GO:0002693///positive regulation of cellular extravasation+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030837///negative regulation of actin filament polymerization+++GO:0034260///negative regulation of GTPase activity+++GO:0035696///monocyte extravasation+++GO:0042060///wound healing+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043542///endothelial cell migration+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050904///diapedesis+++GO:0061028///establishment of endothelial barrier+++GO:0070830///bicellular tight junction assembly+++GO:0072011///glomerular endothelium development+++GO:0072672///neutrophil extravasation+++GO:0090673///endothelial cell-matrix adhesion+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 18616 18616 'Peg3' mRNA 1499 1548 1376 8.48 9.04 8.27 4.5 3.58 4.69 8.596666667 4.256666667 885 697 865 1474.333333 815.6666667 5.16E-20 -0.865715971 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 18617 18617 'Rhox5' mRNA 1 0 0 0.08 0 0 0 0 0.14 0.026666667 0.046666667 0 0 2 0.333333333 0.666666667 0.863090843 0.890645578 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0035234///ectopic germ cell programmed cell death+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048484///enteric nervous system development" 18618 18618 'Pemt' mRNA 63 41 72 4.29 2.79 5.1 3.7 3.64 4.23 4.06 3.856666667 63 61 70 58.66666667 64.66666667 0.798498426 0.120043334 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0031966///mitochondrial membrane+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle GO:0000773///phosphatidyl-N-methylethanolamine N-methyltransferase activity+++GO:0004608///phosphatidylethanolamine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008429///phosphatidylethanolamine binding+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0080101///phosphatidyl-N-dimethylethanolamine N-methyltransferase activity GO:0001835///blastocyst hatching+++GO:0006629///lipid metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0008654///phospholipid biosynthetic process+++GO:0009410///response to xenobiotic stimulus+++GO:0032259///methylation+++GO:0033273///response to vitamin+++GO:0042493///response to drug+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0050747///positive regulation of lipoprotein metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis 18619 18619 'Penk' mRNA 113 99 59 5.29 4.57 2.93 11.25 11.66 11.84 4.263333333 11.58333333 276 279 281 90.33333333 278.6666667 1.92E-14 1.622543849 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0032280///symmetric synapse+++GO:0034466///chromaffin granule lumen+++GO:0034592///synaptic vesicle lumen+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0070852///cell body fiber+++GO:0099013///neuronal dense core vesicle lumen GO:0001515///opioid peptide activity+++GO:0031628///opioid receptor binding "GO:0001649///osteoblast differentiation+++GO:0001662///behavioral fear response+++GO:0001666///response to hypoxia+++GO:0001964///startle response+++GO:0002118///aggressive behavior+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007568///aging+++GO:0007600///sensory perception+++GO:0007626///locomotory behavior+++GO:0009314///response to radiation+++GO:0009617///response to bacterium+++GO:0009636///response to toxic substance+++GO:0014009///glial cell proliferation+++GO:0019233///sensory perception of pain+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034599///cellular response to oxidative stress+++GO:0035094///response to nicotine+++GO:0035641///locomotory exploration behavior+++GO:0043278///response to morphine+++GO:0045471///response to ethanol+++GO:0051592///response to calcium ion+++GO:0051867///general adaptation syndrome, behavioral process+++GO:0071305///cellular response to vitamin D+++GO:0071320///cellular response to cAMP+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071871///response to epinephrine+++GO:0098586///cellular response to virus+++GO:0099538///synaptic signaling via neuropeptide+++GO:2000987///positive regulation of behavioral fear response" 18624 18624 'Pepd' mRNA 1796 1723 1671 55.67 52.63 54.94 67.25 75.36 71.75 54.41333333 71.45333333 2494 2725 2570 1730 2596.333333 9.95E-15 0.575157589 GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0102009///proline dipeptidase activity GO:0006508///proteolysis+++GO:0030574///collagen catabolic process 18626 18626 'Per1' mRNA 2404 2201 1219 26.47 23.88 14 16.9 15.88 16.52 21.45 16.43333333 1780 1618 1677 1941.333333 1691.666667 0.565603422 -0.197465834 04710///Circadian rhythm+++04713///Circadian entrainment GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019900///kinase binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0070888///E-box binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002028///regulation of sodium ion transport+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0032922///circadian regulation of gene expression+++GO:0042634///regulation of hair cycle+++GO:0042752///regulation of circadian rhythm+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0048511///rhythmic process+++GO:0051591///response to cAMP+++GO:0070932///histone H3 deacetylation+++GO:0097167///circadian regulation of translation+++GO:1900015///regulation of cytokine production involved in inflammatory response+++GO:1900744///regulation of p38MAPK cascade+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway" 18627 18627 'Per2' mRNA 1089 1046 1055 9.92 9.36 10.19 6.41 5.75 6.23 9.823333333 6.13 811 711 764 1063.333333 762 1.53E-07 -0.494024905 04710///Circadian rhythm+++04711///Circadian rhythm - fly+++04713///Circadian entrainment+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019900///kinase binding+++GO:0035257///nuclear hormone receptor binding+++GO:0036002///pre-mRNA binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0070063///RNA polymerase binding+++GO:1990226///histone methyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002931///response to ischemia+++GO:0005978///glycogen biosynthetic process+++GO:0006094///gluconeogenesis+++GO:0006631///fatty acid metabolic process+++GO:0007623///circadian rhythm+++GO:0019229///regulation of vasoconstriction+++GO:0019249///lactate biosynthetic process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0042754///negative regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis+++GO:0050796///regulation of insulin secretion+++GO:0050872///white fat cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0051946///regulation of glutamate uptake involved in transmission of nerve impulse+++GO:0060567///negative regulation of DNA-templated transcription, termination+++GO:0070345///negative regulation of fat cell proliferation+++GO:0070932///histone H3 deacetylation+++GO:0097167///circadian regulation of translation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2000678///negative regulation of transcription regulatory region DNA binding" 18628 18628 'Per3' mRNA 2897 2739 2926 25.6 23.84 27.43 15.65 14.33 14.04 25.62333333 14.67333333 2030 1823 1775 2854 1876 1.92E-15 -0.620159297 04710///Circadian rhythm+++04713///Circadian entrainment GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization" 18631 18631 'Pex11a' mRNA 491 520 480 12.17 12.55 12.68 6.61 9.07 7.22 12.46666667 7.633333333 310 413 327 497 350 4.97E-04 -0.514742674 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0042803///protein homodimerization activity GO:0007031///peroxisome organization+++GO:0007165///signal transduction+++GO:0016557///peroxisome membrane biogenesis+++GO:0016559///peroxisome fission+++GO:0044375///regulation of peroxisome size+++GO:0050873///brown fat cell differentiation 18632 18632 'Pex11b' mRNA 756 800 813 26.54 24.8 28 23.97 24.62 26.95 26.44666667 25.18 827 800 836 789.6666667 821 0.752904861 0.042785331 04146///Peroxisome GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0007031///peroxisome organization+++GO:0007165///signal transduction+++GO:0016559///peroxisome fission+++GO:0044375///regulation of peroxisome size 18633 18633 'Pex16' mRNA 745 804 755 30.01 32.05 32.37 26.1 28.64 25.4 31.47666667 26.71333333 742 796 702 768 746.6666667 0.714533256 -0.051773892 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008022///protein C-terminus binding GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0016557///peroxisome membrane biogenesis+++GO:0016558///protein import into peroxisome matrix+++GO:0022615///protein to membrane docking+++GO:0032581///ER-dependent peroxisome organization+++GO:0045046///protein import into peroxisome membrane+++GO:0106101///ER-dependent peroxisome localization 18634 18634 'Pex7' mRNA 832 836 777 25.19 24.92 24.95 21.12 22.71 23.11 25.02 22.31333333 802 842 849 815 831 0.886419618 0.017739557 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol GO:0005053///peroxisome matrix targeting signal-2 binding+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity GO:0001764///neuron migration+++GO:0001958///endochondral ossification+++GO:0006625///protein targeting to peroxisome+++GO:0006635///fatty acid beta-oxidation+++GO:0007031///peroxisome organization+++GO:0008611///ether lipid biosynthetic process+++GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix 18636 18636 'Cfp' mRNA 129 119 134 4.6 4.19 5.07 125.08 126.7 124.2 4.62 125.3266667 4029 3983 3871 127.3333333 3961 0 4.947275423 05168///Herpes simplex virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule "GO:0002376///immune system process+++GO:0006957///complement activation, alternative pathway+++GO:0045087///innate immune response" 18637 18637 'Pfdn2' mRNA 712.86 766.26 710.06 23.86 25.26 25.2 24.23 24.33 22.45 24.77333333 23.67 832.3 815.64 746.36 729.7266667 798.1 0.31199198 0.117616913 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016272///prefoldin complex GO:0001540///amyloid-beta binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0051495///positive regulation of cytoskeleton organization+++GO:1905907///negative regulation of amyloid fibril formation 18639 18639 'Pfkfb1' mRNA 8 10 8 0.27 0.33 0.26 0.43 0.51 0.71 0.286666667 0.55 15 19 27 8.666666667 20.33333333 0.084333026 1.223501371 00051///Fructose and mannose metabolism+++04152///AMPK signaling pathway+++04922///Glucagon signaling pathway "GO:0005829///cytosol+++GO:0043540///6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex" "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003873///6-phosphofructo-2-kinase activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0070095///fructose-6-phosphate binding" "GO:0006000///fructose metabolic process+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0031100///animal organ regeneration+++GO:0032868///response to insulin+++GO:0033133///positive regulation of glucokinase activity+++GO:0033762///response to glucagon+++GO:0042594///response to starvation+++GO:0046835///carbohydrate phosphorylation+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP" 18640 18640 'Pfkfb2' mRNA 946.76 922.74 970.68 9.73 9.39 10.82 6.51 5.45 5.84 9.98 5.933333333 736.8 596 633.16 946.7266667 655.32 3.78E-07 -0.54561528 00051///Fructose and mannose metabolism+++04152///AMPK signaling pathway+++04919///Thyroid hormone signaling pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003873///6-phosphofructo-2-kinase activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding" "GO:0006000///fructose metabolic process+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0006007///glucose catabolic process+++GO:0006089///lactate metabolic process+++GO:0006090///pyruvate metabolic process+++GO:0006096///glycolytic process+++GO:0008152///metabolic process+++GO:0009749///response to glucose+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0032024///positive regulation of insulin secretion+++GO:0033133///positive regulation of glucokinase activity+++GO:0046835///carbohydrate phosphorylation" 18641 18641 'Pfkl' mRNA 8394 8757 8264 121.9 125.09 127.33 96.26 91.23 93.62 124.7733333 93.70333333 7633 7065 7189 8471.666667 7295.666667 2.14E-05 -0.227882689 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway+++04152///AMPK signaling pathway+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005945///6-phosphofructokinase complex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003872///6-phosphofructokinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding+++GO:0070061///fructose binding+++GO:0070095///fructose-6-phosphate binding "GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0008152///metabolic process+++GO:0009749///response to glucose+++GO:0016310///phosphorylation+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0046676///negative regulation of insulin secretion+++GO:0061615///glycolytic process through fructose-6-phosphate+++GO:0061621///canonical glycolysis" 18642 18642 'Pfkm' mRNA 2927 2954 2759 56.13 55.88 56.3 25.29 23.97 25 56.10333333 24.75333333 1509 1397 1448 2880 1451.333333 1.89E-53 -1.000273051 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway+++04152///AMPK signaling pathway+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005945///6-phosphofructokinase complex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003872///6-phosphofructokinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008443///phosphofructokinase activity+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding+++GO:0070061///fructose binding+++GO:0070095///fructose-6-phosphate binding "GO:0005980///glycogen catabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0032024///positive regulation of insulin secretion+++GO:0042593///glucose homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046716///muscle cell cellular homeostasis+++GO:0046835///carbohydrate phosphorylation+++GO:0061615///glycolytic process through fructose-6-phosphate+++GO:0061621///canonical glycolysis+++GO:0093001///glycolysis from storage polysaccharide through glucose-1-phosphate" 18643 18643 'Pfn1' mRNA 3834.98 3774.41 3488.19 292.57 284.8 282.39 1026.66 1104.22 1068.99 286.5866667 1066.623333 15418.02 16155.44 15506.47 3699.193333 15693.31 0 2.075045619 04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++05014///Amyotrophic lateral sclerosis+++05131///Shigellosis+++05132///Salmonella infection GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0001784///phosphotyrosine residue binding+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0031267///small GTPase binding+++GO:0070064///proline-rich region binding" GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0010033///response to organic substance+++GO:0010634///positive regulation of epithelial cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030833///regulation of actin filament polymerization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032781///positive regulation of ATPase activity+++GO:0042989///sequestering of actin monomers+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050434///positive regulation of viral transcription+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0060074///synapse maturation+++GO:0071363///cellular response to growth factor stimulus+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:1900029///positive regulation of ruffle assembly 18645 18645 'Pfn2' mRNA 1315 1417 1169 37.02 39.3 34.92 33.4 30.48 33.4 37.08 32.42666667 1364 1215 1320 1300.333333 1299.666667 0.927390242 -0.010359717 04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++05014///Amyotrophic lateral sclerosis+++05131///Shigellosis+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0043195///terminal bouton+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0016887///ATPase activity" GO:0010633///negative regulation of epithelial cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030833///regulation of actin filament polymerization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032781///positive regulation of ATPase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0050821///protein stabilization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:1900028///negative regulation of ruffle assembly+++GO:2000300///regulation of synaptic vesicle exocytosis 18646 18646 'Prf1' mRNA 4 5 8 0.11 0.14 0.18 0.36 0.39 0.5 0.143333333 0.416666667 19 19 21 5.666666667 19.66666667 0.018523771 1.774678194 04210///Apoptosis+++04650///Natural killer cell mediated cytotoxicity+++04940///Type I diabetes mellitus+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031904///endosome lumen+++GO:0044194///cytolytic granule GO:0005509///calcium ion binding+++GO:0022829///wide pore channel activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001771///immunological synapse formation+++GO:0001913///T cell mediated cytotoxicity+++GO:0002357///defense response to tumor cell+++GO:0002418///immune response to tumor cell+++GO:0006915///apoptotic process+++GO:0007623///circadian rhythm+++GO:0019835///cytolysis+++GO:0051260///protein homooligomerization+++GO:0051607///defense response to virus+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0055085///transmembrane transport 18647 18647 'Cdk14' mRNA 1092 1199 1070 11.97 12.85 12.36 4.16 4.21 4.07 12.39333333 4.146666667 442 428 413 1120.333333 427.6666667 2.29E-47 -1.400311292 05202///Transcriptional misregulation in cancer GO:0000308///cytoplasmic cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0060828///regulation of canonical Wnt signaling pathway 18648 18648 'Pgam1' mRNA 14361 14994 14047 450.83 463.87 467.82 474.39 457.85 466.12 460.84 466.12 17369 16363 16516 14467.33333 16749.33333 4.90E-05 0.199349618 "00010///Glycolysis / Gluconeogenesis+++00260///Glycine, serine and threonine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0097228///sperm principal piece "GO:0003824///catalytic activity+++GO:0004082///bisphosphoglycerate mutase activity+++GO:0004619///phosphoglycerate mutase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0019901///protein kinase binding" GO:0006096///glycolytic process+++GO:0006110///regulation of glycolytic process+++GO:0043456///regulation of pentose-phosphate shunt+++GO:0045730///respiratory burst 18654 18654 'Pgf' mRNA 27 28 38 1.15 0.99 1.63 2.14 2.19 1.82 1.256666667 2.05 68 66 52 31 62 0.011756756 0.981114724 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane GO:0005172///vascular endothelial growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0031100///animal organ regeneration+++GO:0032870///cellular response to hormone stimulus+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0042493///response to drug+++GO:0045766///positive regulation of angiogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0060688///regulation of morphogenesis of a branching structure+++GO:0060754///positive regulation of mast cell chemotaxis 18655 18655 'Pgk1' mRNA 5625 5615 5604 177.34 174.46 187.44 208.3 202.19 203.03 179.7466667 204.5066667 7594 7195 7163 5614.666667 7317.333333 8.16E-11 0.3690601 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0004618///phosphoglycerate kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043531///ADP binding+++GO:0047134///protein-disulfide reductase activity GO:0005975///carbohydrate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0030855///epithelial cell differentiation+++GO:0031639///plasminogen activation+++GO:0071456///cellular response to hypoxia 18667 18667 'Pgr' mRNA 151.86 102.4 135.01 0.97 0.63 0.94 0.31 0.2 0.35 0.846666667 0.286666667 58.01 33.01 55 129.7566667 48.67333333 2.29E-06 -1.428559079 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0043679///axon terminus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001225///RNA polymerase II transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding" "GO:0001542///ovulation from ovarian follicle+++GO:0002070///epithelial cell maturation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030879///mammary gland development+++GO:0038001///paracrine signaling+++GO:0042220///response to cocaine+++GO:0043066///negative regulation of apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0050678///regulation of epithelial cell proliferation+++GO:0050847///progesterone receptor signaling pathway+++GO:0060180///female mating behavior+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:1904709///negative regulation of granulosa cell apoptotic process" 18669 18669 'Abcb1b' mRNA 22.62 21.59 12.42 0.28 0.26 0.21 2.07 1.69 1.57 0.25 1.776666667 181.6 153.58 141.51 18.87666667 158.8966667 6.18E-23 3.102798461 02010///ABC transporters+++04976///Bile secretion+++05206///MicroRNAs in cancer+++05226///Gastric cancer GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0046581///intercellular canaliculus+++GO:0098591///external side of apical plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity+++GO:0099038///ceramide-translocating ATPase activity" GO:0000086///G2/M transition of mitotic cell cycle+++GO:0009410///response to xenobiotic stimulus+++GO:0014045///establishment of endothelial blood-brain barrier+++GO:0042493///response to drug+++GO:0045332///phospholipid translocation+++GO:0047484///regulation of response to osmotic stress+++GO:0055085///transmembrane transport+++GO:0061843///Sertoli cell barrier remodeling+++GO:0070633///transepithelial transport+++GO:0072089///stem cell proliferation+++GO:0099040///ceramide translocation+++GO:0140115///export across plasma membrane+++GO:1901529///positive regulation of anion channel activity+++GO:1905039///carboxylic acid transmembrane transport+++GO:1990961///drug transmembrane export+++GO:1990962///drug transport across blood-brain barrier+++GO:2001225///regulation of chloride transport 18670 18670 'Abcb4' mRNA 85 80 45 1.19 1.1 0.67 0.61 0.4 0.71 0.986666667 0.573333333 49 33 53 70 45 0.099988292 -0.640233199 02010///ABC transporters+++04976///Bile secretion GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft+++GO:0046581///intercellular canaliculus "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity+++GO:0099038///ceramide-translocating ATPase activity" GO:0006855///drug transmembrane transport+++GO:0006869///lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0032782///bile acid secretion+++GO:0045332///phospholipid translocation+++GO:0055088///lipid homeostasis+++GO:0061092///positive regulation of phospholipid translocation+++GO:1901557///response to fenofibrate+++GO:1903413///cellular response to bile acid+++GO:2001140///positive regulation of phospholipid transport 18671 18671 'Abcb1a' mRNA 404.38 405.41 419.58 4.17 4.11 4.59 3.51 3.03 3.11 4.29 3.216666667 392.4 330.42 336.49 409.79 353.1033333 0.12531125 -0.22956578 02010///ABC transporters+++04976///Bile secretion+++05206///MicroRNAs in cancer+++05226///Gastric cancer GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0046581///intercellular canaliculus "GO:0000121///glycerol-1-phosphatase activity+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0008967///phosphoglycolate phosphatase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0043136///glycerol-3-phosphatase activity+++GO:0046872///metal ion binding+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides+++GO:0099038///ceramide-translocating ATPase activity" GO:0000086///G2/M transition of mitotic cell cycle+++GO:0005975///carbohydrate metabolic process+++GO:0006114///glycerol biosynthetic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006855///drug transmembrane transport+++GO:0006869///lipid transport+++GO:0009914///hormone transport+++GO:0016311///dephosphorylation+++GO:0032376///positive regulation of cholesterol transport+++GO:0032782///bile acid secretion+++GO:0033231///carbohydrate export+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042908///xenobiotic transport+++GO:0043215///daunorubicin transport+++GO:0045332///phospholipid translocation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046865///terpenoid transport+++GO:0047484///regulation of response to osmotic stress+++GO:0050892///intestinal absorption+++GO:0055085///transmembrane transport+++GO:0055088///lipid homeostasis+++GO:0060548///negative regulation of cell death+++GO:0060856///establishment of blood-brain barrier+++GO:0061092///positive regulation of phospholipid translocation+++GO:0070633///transepithelial transport+++GO:0072089///stem cell proliferation+++GO:0099040///ceramide translocation+++GO:0140115///export across plasma membrane+++GO:1901529///positive regulation of anion channel activity+++GO:1901557///response to fenofibrate+++GO:1902396///protein localization to bicellular tight junction+++GO:1903413///cellular response to bile acid+++GO:1904446///positive regulation of establishment of Sertoli cell barrier+++GO:1904478///regulation of intestinal absorption+++GO:1905039///carboxylic acid transmembrane transport+++GO:1990961///drug transmembrane export+++GO:1990962///drug transport across blood-brain barrier+++GO:1990963///establishment of blood-retinal barrier+++GO:2001025///positive regulation of response to drug+++GO:2001140///positive regulation of phospholipid transport+++GO:2001225///regulation of chloride transport 18673 18673 'Phb' mRNA 2531 2505 2464 81.09 79.1 83.75 82.07 87.91 82.01 81.31333333 83.99666667 2944 3078 2847 2500 2956.333333 0.001286496 0.230209258 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030061///mitochondrial crista+++GO:0031315///extrinsic component of mitochondrial outer membrane+++GO:0035632///mitochondrial prohibitin complex+++GO:0043209///myelin sheath+++GO:0098891///extrinsic component of presynaptic active zone membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0001850///complement component C3a binding+++GO:0001851///complement component C3b binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0031871///proteinase activated receptor binding+++GO:0042826///histone deacetylase binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0001552///ovarian follicle atresia+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007005///mitochondrion organization+++GO:0007202///activation of phospholipase C activity+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0016575///histone deacetylation+++GO:0023035///CD40 signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0031100///animal organ regeneration+++GO:0032740///positive regulation of interleukin-17 production+++GO:0034097///response to cytokine+++GO:0035902///response to immobilization stress+++GO:0039529///RIG-I signaling pathway+++GO:0042113///B cell activation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0044830///modulation by host of viral RNA genome replication+++GO:0045471///response to ethanol+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045917///positive regulation of complement activation+++GO:0046718///viral entry into host cell+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050821///protein stabilization+++GO:0050847///progesterone receptor signaling pathway+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071354///cellular response to interleukin-6+++GO:0071897///DNA biosynthetic process+++GO:0072538///T-helper 17 type immune response+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1990051///activation of protein kinase C activity+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway" 18674 18674 'Slc25a3' mRNA 12031 11668 11298 470.42 449.92 468.66 444.95 449.3 453.12 463 449.1233333 13088 12884 12902 11665.66667 12958 0.007707403 0.139935761 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0043209///myelin sheath GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0044877///protein-containing complex binding GO:0035435///phosphate ion transmembrane transport+++GO:1990547///mitochondrial phosphate ion transmembrane transport 18675 18675 'Phex' mRNA 10.3 14.01 2 0.09 0.12 0.02 0.14 0.08 0.11 0.076666667 0.11 19 10 15.02 8.77 14.67333333 0.413104814 0.765902448 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0019637///organophosphate metabolic process+++GO:0030282///bone mineralization+++GO:0030324///lung development+++GO:0031214///biomineral tissue development+++GO:0033280///response to vitamin D+++GO:0042476///odontogenesis+++GO:0060348///bone development+++GO:0060416///response to growth hormone+++GO:0071305///cellular response to vitamin D+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:1904383///response to sodium phosphate+++GO:1990418///response to insulin-like growth factor stimulus 18676 18676 'Phf2' mRNA 512 484 322 5.19 4.82 3.46 3.48 3.12 3.45 4.49 3.35 395 346 380 439.3333333 373.6666667 0.171768029 -0.237886177 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus" GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0035575///histone demethylase activity (H4-K20 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0033169///histone H3-K9 demethylation+++GO:0035574///histone H4-K20 demethylation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0061188///negative regulation of chromatin silencing at rDNA" 18679 18679 'Phka1' mRNA 736 752 764 6.52 6.66 7.25 4.7 4.13 4.19 6.81 4.34 604 526 529 750.6666667 553 3.79E-05 -0.455055252 04020///Calcium signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005886///plasma membrane+++GO:0005964///phosphorylase kinase complex+++GO:0016020///membrane GO:0005516///calmodulin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation 18682 18682 'Phkg1' mRNA 45.14 54.82 49.68 1.08 1.28 1.37 1.21 0.88 1.04 1.243333333 1.043333333 57.59 40.85 48.89 49.88 49.11 0.926028199 -0.043738701 04020///Calcium signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005964///phosphorylase kinase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004689///phosphorylase kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0050321///tau-protein kinase activity GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 18685 18685 'Phtf1' mRNA 570 527 431 12.7 11.41 10.78 6.47 4.89 5.45 11.63 5.603333333 309 224 262 509.3333333 265 1.12E-10 -0.95246269 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008150///biological_process 18693 18693 'Pick1' mRNA 1735 1773 1803 49.9 50.25 55.07 29.08 29.45 29.25 51.74 29.26 1161 1147 1131 1770.333333 1146.333333 1.77E-15 -0.640187692 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032588///trans-Golgi network membrane+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098842///postsynaptic early endosome+++GO:0098843///postsynaptic endocytic zone+++GO:0098978///glutamatergic synapse GO:0001664///G protein-coupled receptor binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005102///signaling receptor binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008022///protein C-terminus binding+++GO:0008092///cytoskeletal protein binding+++GO:0016301///kinase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0071933///Arp2/3 complex binding+++GO:0140090///membrane curvature sensor activity GO:0002092///positive regulation of receptor internalization+++GO:0006468///protein phosphorylation+++GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0010629///negative regulation of gene expression+++GO:0015844///monoamine transport+++GO:0016310///phosphorylation+++GO:0021782///glial cell development+++GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0035556///intracellular signal transduction+++GO:0036294///cellular response to decreased oxygen levels+++GO:0042149///cellular response to glucose starvation+++GO:0043113///receptor clustering+++GO:0050796///regulation of insulin secretion+++GO:0050803///regulation of synapse structure or activity+++GO:0060292///long-term synaptic depression+++GO:0060548///negative regulation of cell death+++GO:0061025///membrane fusion+++GO:0097061///dendritic spine organization+++GO:0097062///dendritic spine maintenance+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization 18700 18700 'Piga' mRNA 137 179 158 1.95 2.47 2.41 2.25 2.35 2.49 2.276666667 2.363333333 180 182 189 158 183.6666667 0.373282757 0.205859419 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity" GO:0006506///GPI anchor biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 18701 18701 'Pigf' mRNA 320.64 335.69 360.92 21.02 21.77 25.11 20.63 21.42 21.98 22.63333333 21.34333333 360.31 365.05 371.29 339.0833333 365.55 0.593548374 0.096762511 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0051377///mannose-ethanolamine phosphotransferase activity" GO:0006506///GPI anchor biosynthetic process 18703 18703 'Pigr' mRNA 1.13 0 1 0.02 0 0.01 0.22 0.06 0.01 0.01 0.096666667 18 5.08 1.03 0.71 8.036666667 0.040830226 3.546170254 04672///Intestinal immune network for IgA production GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0043235///receptor complex+++GO:0055038///recycling endosome membrane+++GO:0071751///secretory IgA immunoglobulin complex GO:0001792///polymeric immunoglobulin receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005154///epidermal growth factor receptor binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0002415///immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0038093///Fc receptor signaling pathway+++GO:0043113///receptor clustering 18704 18704 'Pik3c2a' mRNA 914.44 1036.6 799.85 5.99 6.67 5.57 7.95 6.75 7.37 6.076666667 7.356666667 1402.09 1159.86 1255.46 916.9633333 1272.47 2.70E-06 0.463815493 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0030276///clathrin binding+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0035091///phosphatidylinositol binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity" GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0009267///cellular response to starvation+++GO:0010508///positive regulation of autophagy+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016236///macroautophagy+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0071583///negative regulation of zinc ion transmembrane transport+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1905037///autophagosome organization 18705 18705 'Pik3c2g' mRNA 39 38 36 0.47 0.48 0.5 0.29 0.3 0.33 0.483333333 0.306666667 35 31 30 37.66666667 32 0.636398589 -0.247239622 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++05132///Salmonella infection GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0035091///phosphatidylinositol binding+++GO:0052742///phosphatidylinositol kinase activity GO:0006935///chemotaxis+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0039694///viral RNA genome replication+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling 18706 18706 'Pik3ca' mRNA 631 675.01 697.38 4.77 5.01 5.59 4.24 3.93 4.55 5.123333333 4.24 645.3 584.95 672.02 667.7966667 634.09 0.526928453 -0.089655936 "00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005943///phosphatidylinositol 3-kinase complex, class IA+++GO:0005944///phosphatidylinositol 3-kinase complex, class IB+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0030027///lamellipodium" "GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0030295///protein kinase activator activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0043560///insulin receptor substrate binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity" GO:0001525///angiogenesis+++GO:0001889///liver development+++GO:0001932///regulation of protein phosphorylation+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0032147///activation of protein kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035994///response to muscle stretch+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0040014///regulation of multicellular organism growth+++GO:0043457///regulation of cellular respiration+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044029///hypomethylation of CpG island+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055119///relaxation of cardiac muscle+++GO:0060612///adipose tissue development+++GO:0071333///cellular response to glucose stimulus+++GO:0071464///cellular response to hydrostatic pressure+++GO:0086003///cardiac muscle cell contraction+++GO:0097009///energy homeostasis+++GO:0110053///regulation of actin filament organization+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:2000653///regulation of genetic imprinting+++GO:2000811///negative regulation of anoikis 18707 18707 'Pik3cd' mRNA 132 153 176 1.46 1.7 2.12 8.23 7.72 7.86 1.76 7.936666667 861 798 807 153.6666667 822 9.19E-69 2.40360256 "00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity" GO:0001782///B cell homeostasis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007166///cell surface receptor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:0042113///B cell activation+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048872///homeostasis of number of cells+++GO:0050832///defense response to fungus+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1905278///positive regulation of epithelial tube formation 18708 18708 'Pik3r1' mRNA 2010 2013 1627 15.32 15.09 13.21 10.56 9.51 9.27 14.54 9.78 1594 1404 1360 1883.333333 1452.666667 9.04E-06 -0.383470923 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005943///phosphatidylinositol 3-kinase complex, class IA+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:1990578///perinuclear endoplasmic reticulum membrane" GO:0001784///phosphotyrosine residue binding+++GO:0005102///signaling receptor binding+++GO:0005158///insulin receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0043125///ErbB-3 class receptor binding+++GO:0043559///insulin binding+++GO:0043560///insulin receptor substrate binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity+++GO:0046982///protein heterodimerization activity+++GO:0051117///ATPase binding+++GO:0051219///phosphoprotein binding GO:0001678///cellular glucose homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0006606///protein import into nucleus+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010459///negative regulation of heart rate+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010628///positive regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0015031///protein transport+++GO:0016310///phosphorylation+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030183///B cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0033120///positive regulation of RNA splicing+++GO:0034644///cellular response to UV+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045776///negative regulation of blood pressure+++GO:0045861///negative regulation of proteolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050821///protein stabilization+++GO:0051384///response to glucocorticoid+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051591///response to cAMP+++GO:0051965///positive regulation of synapse assembly+++GO:0060396///growth hormone receptor signaling pathway+++GO:0120183///positive regulation of focal adhesion disassembly+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1903076///regulation of protein localization to plasma membrane 18709 18709 'Pik3r2' mRNA 2274 2179 2223 39.27 37.02 40.7 26.32 26.36 25.33 38.99666667 26.00333333 1756 1717 1636 2225.333333 1703 9.14E-08 -0.398830116 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005942///phosphatidylinositol 3-kinase complex GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019903///protein phosphatase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity+++GO:0046982///protein heterodimerization activity GO:0001678///cellular glucose homeostasis+++GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0010506///regulation of autophagy+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0015031///protein transport+++GO:0030833///regulation of actin filament polymerization+++GO:0032869///cellular response to insulin stimulus+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043409///negative regulation of MAPK cascade+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0051492///regulation of stress fiber assembly+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1903076///regulation of protein localization to plasma membrane 18710 18710 'Pik3r3' mRNA 952 1051 994 9.64 10.45 10.78 6.19 5.92 6.52 10.29 6.21 708 654 718 999 693.3333333 3.05E-08 -0.539382397 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005942///phosphatidylinositol 3-kinase complex GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0001934///positive regulation of protein phosphorylation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0008286///insulin receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0043491///protein kinase B signaling+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0046854///phosphatidylinositol phosphorylation 18711 18711 'Pikfyve' mRNA 429 439 438 1.98 2 2.15 2.64 2.31 2.2 2.043333333 2.383333333 654 564 532 435.3333333 583.3333333 0.001206507 0.408259695 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04145///Phagosome+++04810///Regulation of actin cytoskeleton GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0010008///endosome membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032593///insulin-responsive compartment+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000285///1-phosphatidylinositol-3-phosphate 5-kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0052810///1-phosphatidylinositol-5-kinase activity "GO:0006612///protein targeting to membrane+++GO:0016310///phosphorylation+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030593///neutrophil chemotaxis+++GO:0032288///myelin assembly+++GO:0032438///melanosome organization+++GO:0034504///protein localization to nucleus+++GO:0035556///intracellular signal transduction+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043312///neutrophil degranulation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0090382///phagosome maturation+++GO:0090385///phagosome-lysosome fusion+++GO:1903100///1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1904562///phosphatidylinositol 5-phosphate metabolic process+++GO:2000785///regulation of autophagosome assembly" 18712 18712 'Pim1' mRNA 207 179 206 5.37 4.21 6.06 8.8 7.12 8.85 5.213333333 8.256666667 407 351 394 197.3333333 384 1.22E-09 0.945601492 04630///JAK-STAT signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0043024///ribosomal small subunit binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0022898///regulation of transmembrane transporter activity+++GO:0030212///hyaluronan metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0070561///vitamin D receptor signaling pathway+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:1902033///regulation of hematopoietic stem cell proliferation+++GO:1905062///positive regulation of cardioblast proliferation+++GO:1990748///cellular detoxification" 18715 18715 'Pim2' mRNA 539 475 482 15 13.02 14.23 6.97 8.41 7.83 14.08333333 7.736666667 288 339 313 498.6666667 313.3333333 6.94E-07 -0.680773264 05200///Pathways in cancer+++05221///Acute myeloid leukemia GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0008637///apoptotic mitochondrial changes+++GO:0010508///positive regulation of autophagy+++GO:0016239///positive regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization" 18717 18717 'Pip5k1c' mRNA 1936 1983 1859 24.62 24.87 25.1 17.9 20.43 19.97 24.86333333 19.43333333 1617 1802 1747 1926 1722 0.042863205 -0.171662743 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05231///Choline metabolism in cancer GO:0001891///phagocytic cup+++GO:0001931///uropod+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0098835///presynaptic endocytic zone membrane+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:1990147///talin binding GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0006909///phagocytosis+++GO:0006935///chemotaxis+++GO:0007155///cell adhesion+++GO:0007409///axonogenesis+++GO:0016310///phosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0070527///platelet aggregation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1900242///regulation of synaptic vesicle endocytosis 18718 18718 'Pip4k2a' mRNA 338 284 256 5.34 4.38 4.28 5.31 5.69 5.46 4.666666667 5.486666667 384 402 389 292.6666667 391.6666667 0.006323198 0.411900098 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04810///Regulation of actin cytoskeleton GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016309///1-phosphatidylinositol-5-phosphate 4-kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity "GO:0010506///regulation of autophagy+++GO:0016310///phosphorylation+++GO:0035855///megakaryocyte development+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0061909///autophagosome-lysosome fusion+++GO:0090119///vesicle-mediated cholesterol transport+++GO:0090217///negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:1902635///1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process+++GO:2000786///positive regulation of autophagosome assembly" 18719 18719 'Pip5k1b' mRNA 404 462 443 8.73 9.82 10.15 10.03 8.75 9.19 9.566666667 9.323333333 534 455 474 436.3333333 487.6666667 0.322483223 0.146660593 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05231///Choline metabolism in cancer GO:0001931///uropod+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity GO:0006661///phosphatidylinositol biosynthetic process+++GO:0016310///phosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation 18720 18720 'Pip5k1a' mRNA 547 603 504 8.52 8.91 8.41 7.51 6.82 7.88 8.613333333 7.403333333 541 495 569 551.3333333 535 0.739528664 -0.053112202 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05231///Choline metabolism in cancer GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding GO:0006661///phosphatidylinositol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010761///fibroblast migration+++GO:0016310///phosphorylation+++GO:0031532///actin cytoskeleton reorganization+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048041///focal adhesion assembly+++GO:0060326///cell chemotaxis+++GO:0072659///protein localization to plasma membrane+++GO:0090630///activation of GTPase activity+++GO:0097178///ruffle assembly 18722 18722 'Pira1' mRNA 27.69 29.13 35.82 0.48 0.52 0.66 8.56 8.45 7.63 0.553333333 8.213333333 556.19 543.62 483.69 30.88 527.8333333 1.07E-86 4.106455873 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001540///amyloid-beta binding+++GO:0003674///molecular_function+++GO:0003712///transcription coregulator activity+++GO:0008127///quercetin 2,3-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process+++GO:0030099///myeloid cell differentiation+++GO:0030224///monocyte differentiation" 18725 18725 'Pira2' mRNA 16.26 10.92 20.3 0.26 0.17 0.34 5.19 5.91 4.44 0.256666667 5.18 375.85 418.74 312.18 15.82666667 368.9233333 1.22E-58 4.572280939 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0032998///Fc-epsilon receptor I complex GO:0001791///IgM binding+++GO:0005102///signaling receptor binding+++GO:0008157///protein phosphatase 1 binding+++GO:0015026///coreceptor activity+++GO:0023025///MHC class Ib protein complex binding+++GO:0023029///MHC class Ib protein binding+++GO:0030107///HLA-A specific inhibitory MHC class I receptor activity+++GO:0030109///HLA-B specific inhibitory MHC class I receptor activity+++GO:0032393///MHC class I receptor activity+++GO:0032394///MHC class Ib receptor activity+++GO:0032396///inhibitory MHC class I receptor activity+++GO:0042169///SH2 domain binding+++GO:0042288///MHC class I protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding GO:0019221///cytokine-mediated signaling pathway 18726 18726 'Lilra6' mRNA 7.75 15.69 20.32 0.2 0.4 0.5 4.76 4.31 4.78 0.366666667 4.616666667 222.79 200.72 215.48 14.58666667 212.9966667 1.42E-34 3.906014308 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005886///plasma membrane GO:0032396///inhibitory MHC class I receptor activity GO:0019221///cytokine-mediated signaling pathway 18733 18733 'Pirb' mRNA 222.52 210.74 193.33 4.52 4.21 4.18 37.77 38.75 36.59 4.303333333 37.70333333 2140.97 2143.4 2003.95 208.8633333 2096.106667 3.47E-256 3.319885205 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding+++GO:0001791///IgM binding+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0023025///MHC class Ib protein complex binding+++GO:0023029///MHC class Ib protein binding+++GO:0030107///HLA-A specific inhibitory MHC class I receptor activity+++GO:0030109///HLA-B specific inhibitory MHC class I receptor activity+++GO:0032393///MHC class I receptor activity+++GO:0032394///MHC class Ib receptor activity+++GO:0032396///inhibitory MHC class I receptor activity+++GO:0042169///SH2 domain binding+++GO:0042288///MHC class I protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding GO:0001782///B cell homeostasis+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007611///learning or memory+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019724///B cell mediated immunity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043011///myeloid dendritic cell differentiation+++GO:0051248///negative regulation of protein metabolic process+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1900454///positive regulation of long-term synaptic depression 18736 18736 'Pou1f1' mRNA 2.74 3.25 4 0.08 0.09 0.12 0.07 0.05 0.05 0.096666667 0.056666667 2.89 1.83 2 3.33 2.24 0.664765373 -0.873141256 "04935///Growth hormone synthesis, secretion and action" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0021983///pituitary gland development+++GO:0021984///adenohypophysis development+++GO:0030183///B cell differentiation+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0040018///positive regulation of multicellular organism growth+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060126///somatotropin secreting cell differentiation+++GO:0060133///somatotropin secreting cell development" 18738 18738 'Pitpna' mRNA 2451 2469 2534 36.45 36.05 39.76 14.75 13.38 14.97 37.42 14.36666667 1175 1014 1137 2484.666667 1108.666667 4.41E-49 -1.178616459 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath GO:0000062///fatty-acyl-CoA binding+++GO:0005543///phospholipid binding+++GO:0005548///phospholipid transporter activity+++GO:0008289///lipid binding+++GO:0008525///phosphatidylcholine transporter activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0070540///stearic acid binding+++GO:0120019///intermembrane phosphotidylcholine transfer activity GO:0007409///axonogenesis+++GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer 18739 18739 'Pitpnm1' mRNA 422.51 394.9 408.05 4.89 4.5 5.01 6.02 5.22 5.53 4.8 5.59 603.14 512.96 537.21 408.4866667 551.1033333 8.81E-04 0.418763165 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0032580///Golgi cisterna membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0005548///phospholipid transporter activity+++GO:0008525///phosphatidylcholine transporter activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding+++GO:0070300///phosphatidic acid binding GO:0015031///protein transport+++GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer 18740 18740 'Pitx1' mRNA 3 0 1 0.08 0 0.03 0 0 0.07 0.036666667 0.023333333 0 0 3 1.333333333 1 0.898013594 -0.419870409 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009653///anatomical structure morphogenesis+++GO:0014707///branchiomeric skeletal muscle development+++GO:0021983///pituitary gland development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048625///myoblast fate commitment+++GO:0051216///cartilage development" 18741 18741 'Pitx2' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04350///TGF-beta signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0051219///phosphoprotein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0002074///extraocular skeletal muscle development+++GO:0003171///atrioventricular valve development+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0003350///pulmonary myocardium development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0007520///myoblast fusion+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009653///anatomical structure morphogenesis+++GO:0009725///response to hormone+++GO:0009887///animal organ morphogenesis+++GO:0016055///Wnt signaling pathway+++GO:0021763///subthalamic nucleus development+++GO:0021855///hypothalamus cell migration+++GO:0021983///pituitary gland development+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0030334///regulation of cell migration+++GO:0031076///embryonic camera-type eye development+++GO:0033189///response to vitamin A+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0035993///deltoid tuberosity development+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042476///odontogenesis+++GO:0043010///camera-type eye development+++GO:0043388///positive regulation of DNA binding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048536///spleen development+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048738///cardiac muscle tissue development+++GO:0055007///cardiac muscle cell differentiation+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0055015///ventricular cardiac muscle cell development+++GO:0055123///digestive system development+++GO:0060412///ventricular septum morphogenesis+++GO:0060460///left lung morphogenesis+++GO:0060577///pulmonary vein morphogenesis+++GO:0060578///superior vena cava morphogenesis+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0061031///endodermal digestive tract morphogenesis+++GO:0061072///iris morphogenesis+++GO:0061325///cell proliferation involved in outflow tract morphogenesis+++GO:0070986///left/right axis specification+++GO:2000288///positive regulation of myoblast proliferation" 18742 18742 'Pitx3' mRNA 3 0 2 0.09 0 0.09 0.04 0 0 0.06 0.013333333 1 0 0 1.666666667 0.333333333 0.495630236 -2.242833484 GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0043025///neuronal cell body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001849///complement component C1q binding+++GO:0001872///(1->3)-beta-D-glucan binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046790///virion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001550///ovarian cumulus expansion+++GO:0001878///response to yeast+++GO:0002088///lens development in camera-type eye+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0007626///locomotory behavior+++GO:0008228///opsonization+++GO:0009653///anatomical structure morphogenesis+++GO:0010468///regulation of gene expression+++GO:0014014///negative regulation of gliogenesis+++GO:0030198///extracellular matrix organization+++GO:0030901///midbrain development+++GO:0035902///response to immobilization stress+++GO:0042220///response to cocaine+++GO:0043278///response to morphine+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0044793///negative regulation by host of viral process+++GO:0044869///negative regulation by host of viral exo-alpha-sialidase activity+++GO:0044871///negative regulation by host of viral glycoprotein metabolic process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046597///negative regulation of viral entry into host cell+++GO:0048666///neuron development+++GO:0050766///positive regulation of phagocytosis+++GO:0050768///negative regulation of neurogenesis+++GO:0070306///lens fiber cell differentiation+++GO:0071542///dopaminergic neuron differentiation+++GO:1903016///negative regulation of exo-alpha-sialidase activity+++GO:1903019///negative regulation of glycoprotein metabolic process+++GO:1904313///response to methamphetamine hydrochloride+++GO:1904935///positive regulation of cell proliferation in midbrain+++GO:1990792///cellular response to glial cell derived neurotrophic factor" 18744 18744 'Pja1' mRNA 2538 2548 2784 53.71 52.6 61.66 40.38 44.34 41.32 55.99 42.01333333 2206 2360 2178 2623.333333 2248 0.007648843 -0.237064973 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process 18746 18746 'Pkm' mRNA 27277 28272 27410 689.9 704.24 735.56 670.88 695.09 667.98 709.9 677.9833333 30496 30834 29380 27653 30236.66667 0.039397077 0.116697832 00010///Glycolysis / Gluconeogenesis+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04922///Glucagon signaling pathway+++04930///Type II diabetes mellitus+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++05230///Central carbon metabolism in cancer GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0043209///myelin sheath+++GO:0062023///collagen-containing extracellular matrix+++GO:1902912///pyruvate kinase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003729///mRNA binding+++GO:0003824///catalytic activity+++GO:0004743///pyruvate kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030955///potassium ion binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0046872///metal ion binding+++GO:0070324///thyroid hormone binding GO:0001889///liver development+++GO:0006006///glucose metabolic process+++GO:0006096///glycolytic process+++GO:0006417///regulation of translation+++GO:0006754///ATP biosynthetic process+++GO:0008152///metabolic process+++GO:0012501///programmed cell death+++GO:0016310///phosphorylation+++GO:0031100///animal organ regeneration+++GO:0032869///cellular response to insulin stimulus+++GO:0042866///pyruvate biosynthetic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:2000767///positive regulation of cytoplasmic translation 18747 18747 'Prkaca' mRNA 817 862 736 20.16 20.91 19.53 19.71 17.35 20.29 20.2 19.11666667 911 785 912 805 869.3333333 0.393268077 0.100534492 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04530///Tight junction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04976///Bile secretion+++05012///Parkinson disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05110///Vibrio cholerae infection+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0044853///plasma membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0097225///sperm midpiece+++GO:0097546///ciliary base+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0004691///cAMP-dependent protein kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030145///manganese ion binding+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0044877///protein-containing complex binding "GO:0001707///mesoderm formation+++GO:0001843///neural tube closure+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0010737///protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0034605///cellular response to heat+++GO:0043457///regulation of cellular respiration+++GO:0045667///regulation of osteoblast differentiation+++GO:0046777///protein autophosphorylation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0048240///sperm capacitation+++GO:0048792///spontaneous exocytosis of neurotransmitter+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051447///negative regulation of meiotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070417///cellular response to cold+++GO:0070613///regulation of protein processing+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071333///cellular response to glucose stimulus+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1990044///protein localization to lipid droplet+++GO:2000810///regulation of bicellular tight junction assembly" 18749 18749 'Prkacb' mRNA 1848 2038 1875 23.39 25.24 25.3 26.06 24.33 25.64 24.64333333 25.34333333 2399 2176 2271 1920.333333 2282 0.001393044 0.236786905 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04530///Tight junction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04742///Taste transduction+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04976///Bile secretion+++05012///Parkinson disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05110///Vibrio cholerae infection+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097546///ciliary base GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0004691///cAMP-dependent protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding GO:0001843///neural tube closure+++GO:0006468///protein phosphorylation+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0010737///protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:0070613///regulation of protein processing+++GO:0097338///response to clozapine+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 18750 18750 'Prkca' mRNA 1259 1162 922 7.71 6.98 6.04 3.14 3.81 3.6 6.91 3.516666667 583 704 660 1114.333333 649 1.53E-11 -0.784686173 "01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05032///Morphine addiction+++05110///Vibrio cholerae infection+++05143///African trypanosomiasis+++05146///Amoebiasis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05214///Glioma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0035866///alphav-beta3 integrin-PKCalpha complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044305///calyx of Held+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0099523///presynaptic cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0035403///histone kinase activity (H3-T6 specific)+++GO:0046872///metal ion binding GO:0000302///response to reactive oxygen species+++GO:0001525///angiogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002026///regulation of the force of heart contraction+++GO:0002062///chondrocyte differentiation+++GO:0002159///desmosome assembly+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006874///cellular calcium ion homeostasis+++GO:0006915///apoptotic process+++GO:0006937///regulation of muscle contraction+++GO:0007155///cell adhesion+++GO:0007611///learning or memory+++GO:0008285///negative regulation of cell proliferation+++GO:0010360///negative regulation of anion channel activity+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032355///response to estradiol+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0035408///histone H3-T6 phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045471///response to ethanol+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045780///positive regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0045822///negative regulation of heart contraction+++GO:0045921///positive regulation of exocytosis+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0047484///regulation of response to osmotic stress+++GO:0048259///regulation of receptor-mediated endocytosis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050930///induction of positive chemotaxis+++GO:0051965///positive regulation of synapse assembly+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070555///response to interleukin-1+++GO:0071322///cellular response to carbohydrate stimulus+++GO:0090330///regulation of platelet aggregation+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000707///positive regulation of dense core granule biogenesis 18751 18751 'Prkcb' mRNA 120 106 87 0.85 0.7 0.55 2.26 1.78 2.11 0.7 2.05 437 327 396 104.3333333 386.6666667 6.65E-26 1.879515357 "01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04150///mTOR signaling pathway+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05032///Morphine addiction+++05140///Leishmaniasis+++05143///African trypanosomiasis+++05146///Amoebiasis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05214///Glioma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008091///spectrin+++GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0044305///calyx of Held+++GO:0099523///presynaptic cytosol GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005080///protein kinase C binding+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035403///histone kinase activity (H3-T6 specific)+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding "GO:0001666///response to hypoxia+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006915///apoptotic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010827///regulation of glucose transmembrane transport+++GO:0010829///negative regulation of glucose transmembrane transport+++GO:0014059///regulation of dopamine secretion+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0035408///histone H3-T6 phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042113///B cell activation+++GO:0042493///response to drug+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071322///cellular response to carbohydrate stimulus+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:2000300///regulation of synaptic vesicle exocytosis" 18752 18752 'Prkcg' mRNA 9 4 9 0.16 0.07 0.18 0.26 0.15 0.18 0.136666667 0.196666667 16 9 11 7.333333333 12 0.479855173 0.685435567 "01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04150///mTOR signaling pathway+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05032///Morphine addiction+++05143///African trypanosomiasis+++05146///Amoebiasis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05214///Glioma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007268///chemical synaptic transmission+++GO:0007611///learning or memory+++GO:0007635///chemosensory behavior+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032095///regulation of response to food+++GO:0032425///positive regulation of mismatch repair+++GO:0035556///intracellular signal transduction+++GO:0042177///negative regulation of protein catabolic process+++GO:0042752///regulation of circadian rhythm+++GO:0043278///response to morphine+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0048265///response to pain+++GO:0048511///rhythmic process+++GO:0050764///regulation of phagocytosis+++GO:0060291///long-term synaptic potentiation+++GO:0060384///innervation+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1990911///response to psychosocial stress+++GO:2000300///regulation of synaptic vesicle exocytosis 18753 18753 'Prkcd' mRNA 1866 1875 1927 37.24 36.84 40.82 48.39 46.25 47.02 38.3 47.22 2784 2609 2634 1889.333333 2675.666667 1.02E-11 0.48830601 04062///Chemokine signaling pathway+++04140///Autophagy - animal+++04270///Vascular smooth muscle contraction+++04361///Axon regeneration+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04722///Neurotrophin signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++05020///Prion disease+++05131///Shigellosis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0036019///endolysosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0099524///postsynaptic cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0004699///calcium-independent protein kinase C activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008047///enzyme activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0043560///insulin receptor substrate binding+++GO:0046872///metal ion binding+++GO:0070976///TIR domain binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0007049///cell cycle+++GO:0016064///immunoglobulin mediated immune response+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0023021///termination of signal transduction+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032079///positive regulation of endodeoxyribonuclease activity+++GO:0032147///activation of protein kinase activity+++GO:0032613///interleukin-10 production+++GO:0032615///interleukin-12 production+++GO:0032930///positive regulation of superoxide anion generation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0032963///collagen metabolic process+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0034599///cellular response to oxidative stress+++GO:0034644///cellular response to UV+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042100///B cell proliferation+++GO:0042119///neutrophil activation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042325///regulation of phosphorylation+++GO:0042742///defense response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0046326///positive regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0051490///negative regulation of filopodium assembly+++GO:0060326///cell chemotaxis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070779///D-aspartate import across plasma membrane+++GO:0071447///cellular response to hydroperoxide+++GO:0090331///negative regulation of platelet aggregation+++GO:0090398///cellular senescence+++GO:1900163///positive regulation of phospholipid scramblase activity+++GO:1904385///cellular response to angiotensin+++GO:2000303///regulation of ceramide biosynthetic process+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:2000753///positive regulation of glucosylceramide catabolic process+++GO:2000755///positive regulation of sphingomyelin catabolic process+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:2001235///positive regulation of apoptotic signaling pathway 18754 18754 'Prkce' mRNA 525 529 335 4.92 4.94 3.4 2.08 1.83 1.62 4.42 1.843333333 266 215 208 463 229.6666667 3.26E-09 -1.016006792 04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04750///Inflammatory mediator regulation of TRP channels+++04925///Aldosterone synthesis and secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis+++05206///MicroRNAs in cancer GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031594///neuromuscular junction+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol GO:0000166///nucleotide binding+++GO:0003785///actin monomer binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0004699///calcium-independent protein kinase C activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008047///enzyme activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030546///receptor activator activity+++GO:0035276///ethanol binding+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding "GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007635///chemosensory behavior+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010763///positive regulation of fibroblast migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019216///regulation of lipid metabolic process+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032024///positive regulation of insulin secretion+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032467///positive regulation of cytokinesis+++GO:0035556///intracellular signal transduction+++GO:0035641///locomotory exploration behavior+++GO:0035669///TRAM-dependent toll-like receptor 4 signaling pathway+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043278///response to morphine+++GO:0043410///positive regulation of MAPK cascade+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0050996///positive regulation of lipid catabolic process+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051301///cell division+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070257///positive regulation of mucus secretion+++GO:0071361///cellular response to ethanol+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071456///cellular response to hypoxia+++GO:0090303///positive regulation of wound healing+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2001031///positive regulation of cellular glucuronidation" 18755 18755 'Prkch' mRNA 301 278 141 4.61 4.19 2.29 3.76 6.83 5.86 3.696666667 5.483333333 283 501 426 240 403.3333333 0.08372661 0.757930296 04270///Vascular smooth muscle contraction+++04750///Inflammatory mediator regulation of TRP channels GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0004699///calcium-independent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060252///positive regulation of glial cell proliferation+++GO:0070528///protein kinase C signaling+++GO:2000810///regulation of bicellular tight junction assembly 18759 18759 'Prkci' mRNA 516 531 245 6.21 6.28 3.13 3.83 3.91 4.69 5.206666667 4.143333333 367 363 434 430.6666667 388 0.575953016 -0.146370698 04015///Rap1 signaling pathway+++04144///Endocytosis+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04611///Platelet activation+++04910///Insulin signaling pathway+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031252///cell leading edge+++GO:0043220///Schmidt-Lanterman incisure+++GO:0045171///intercellular bridge+++GO:0045177///apical part of cell+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005543///phospholipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0034613///cellular protein localization+++GO:0035089///establishment of apical/basal cell polarity+++GO:0035556///intracellular signal transduction+++GO:0042462///eye photoreceptor cell development+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045216///cell-cell junction organization+++GO:0046326///positive regulation of glucose import+++GO:0048194///Golgi vesicle budding+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060252///positive regulation of glial cell proliferation+++GO:0070555///response to interleukin-1+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2000353///positive regulation of endothelial cell apoptotic process 18760 18760 'Prkd1' mRNA 223 277 154 4.59 5.37 4.25 1.05 0.86 1.33 4.736666667 1.08 49 44 65 218 52.66666667 2.03E-15 -2.050588981 04015///Rap1 signaling pathway+++04925///Aldosterone synthesis and secretion+++05208///Chemical carcinogenesis - reactive oxygen species GO:0000421///autophagosome membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007030///Golgi organization+++GO:0007265///Ras protein signal transduction+++GO:0007399///nervous system development+++GO:0010508///positive regulation of autophagy+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010837///regulation of keratinocyte proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030154///cell differentiation+++GO:0031647///regulation of protein stability+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034198///cellular response to amino acid starvation+++GO:0034599///cellular response to oxidative stress+++GO:0035556///intracellular signal transduction+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045087///innate immune response+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048193///Golgi vesicle transport+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0060548///negative regulation of cell death+++GO:0071447///cellular response to hydroperoxide+++GO:0089700///protein kinase D signaling+++GO:1901727///positive regulation of histone deacetylase activity+++GO:2001028///positive regulation of endothelial cell chemotaxis 18761 18761 'Prkcq' mRNA 104 105 107 1.73 1.72 1.89 1.16 1 0.91 1.78 1.023333333 80 68 61 105.3333333 69.66666667 0.028494256 -0.610769409 04064///NF-kappa B signaling pathway+++04140///Autophagy - animal+++04270///Vascular smooth muscle contraction+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04920///Adipocytokine signaling pathway+++04931///Insulin resistance+++05131///Shigellosis+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0001772///immunological synapse+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0031594///neuromuscular junction+++GO:0034451///centriolar satellite+++GO:0042383///sarcolemma GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006954///inflammatory response+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0035556///intracellular signal transduction+++GO:0042102///positive regulation of T cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0050870///positive regulation of T cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051491///positive regulation of filopodium assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051973///positive regulation of telomerase activity+++GO:0060326///cell chemotaxis+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0090330///regulation of platelet aggregation+++GO:1904355///positive regulation of telomere capping+++GO:2000318///positive regulation of T-helper 17 type immune response+++GO:2000570///positive regulation of T-helper 2 cell activation" 18762 18762 'Prkcz' mRNA 1330 1465 1306 14.78 16.56 15.33 6.18 6.16 6.74 15.55666667 6.36 632 608 662 1367 634 1.71E-36 -1.119221732 04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04390///Hippo signaling pathway+++04530///Tight junction+++04611///Platelet activation+++04910///Insulin signaling pathway+++04926///Relaxin signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++05165///Human papillomavirus infection+++05415///Diabetic cardiomyopathy+++05418///Fluid shear stress and atherosclerosis GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016363///nuclear matrix+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0031982///vesicle+++GO:0035748///myelin sheath abaxonal region+++GO:0043203///axon hillock+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045179///apical cortex+++GO:0048471///perinuclear region of cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015459///potassium channel regulator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0043274///phospholipase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007616///long-term memory+++GO:0008284///positive regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0031333///negative regulation of protein complex assembly+++GO:0031584///activation of phospholipase D activity+++GO:0032148///activation of protein kinase B activity+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0032869///cellular response to insulin stimulus+++GO:0034613///cellular protein localization+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0047496///vesicle transport along microtubule+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050806///positive regulation of synaptic transmission+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051222///positive regulation of protein transport+++GO:0051346///negative regulation of hydrolase activity+++GO:0051899///membrane depolarization+++GO:0060081///membrane hyperpolarization+++GO:0060291///long-term synaptic potentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070528///protein kinase C signaling+++GO:0072659///protein localization to plasma membrane+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1990138///neuron projection extension+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000553///positive regulation of T-helper 2 cell cytokine production 18763 18763 'Pkd1' mRNA 4817.38 5186.55 2899 17.01 17.97 11.05 7.74 10.5 9.8 15.34333333 9.346666667 2464.01 3331.5 3075.24 4300.976667 2956.916667 0.054928332 -0.53647943 GO:0002133///polycystin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0031514///motile cilium+++GO:0034703///cation channel complex+++GO:0034704///calcium channel complex+++GO:0042995///cell projection+++GO:0070062///extracellular exosome GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0042813///Wnt-activated receptor activity+++GO:0044325///ion channel binding GO:0001502///cartilage condensation+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0006611///protein export from nucleus+++GO:0006807///nitrogen compound metabolic process+++GO:0006816///calcium ion transport+++GO:0007050///cell cycle arrest+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007259///JAK-STAT cascade+++GO:0007507///heart development+++GO:0016055///Wnt signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:0021510///spinal cord development+++GO:0021915///neural tube development+++GO:0030010///establishment of cell polarity+++GO:0030155///regulation of cell adhesion+++GO:0032092///positive regulation of protein binding+++GO:0034405///response to fluid shear stress+++GO:0036303///lymph vessel morphogenesis+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0043588///skin development+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048565///digestive tract development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048806///genitalia development+++GO:0050982///detection of mechanical stimulus+++GO:0051216///cartilage development+++GO:0051290///protein heterotetramerization+++GO:0051726///regulation of cell cycle+++GO:0060236///regulation of mitotic spindle organization+++GO:0060428///lung epithelium development+++GO:0060674///placenta blood vessel development+++GO:0060854///branching involved in lymph vessel morphogenesis+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070588///calcium ion transmembrane transport+++GO:0072164///mesonephric tubule development+++GO:0072177///mesonephric duct development+++GO:0072205///metanephric collecting duct development+++GO:0072218///metanephric ascending thin limb development+++GO:0072237///metanephric proximal tubule development+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0098609///cell-cell adhesion+++GO:0198738///cell-cell signaling by wnt+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 18764 18764 'Pkd2' mRNA 471.5 512 446 4.67 4.95 4.78 5.26 5 5 4.8 5.086666667 601.32 556 569 476.5 575.44 0.028269254 0.261753642 GO:0002133///polycystin complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005929///cilium+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0031941///filamentous actin+++GO:0034703///cation channel complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045180///basal cortex+++GO:0060170///ciliary membrane+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0072686///mitotic spindle+++GO:0097730///non-motile cilium GO:0005102///signaling receptor binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005267///potassium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0015267///channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0022843///voltage-gated cation channel activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042805///actinin binding+++GO:0043398///HLH domain binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0048763///calcium-induced calcium release activity+++GO:0051117///ATPase binding+++GO:0051219///phosphoprotein binding+++GO:0051371///muscle alpha-actinin binding+++GO:0051393///alpha-actinin binding "GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0001947///heart looping+++GO:0003127///detection of nodal flow+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007259///JAK-STAT cascade+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0021510///spinal cord development+++GO:0021915///neural tube development+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0034765///regulation of ion transmembrane transport+++GO:0035502///metanephric part of ureteric bud development+++GO:0035725///sodium ion transmembrane transport+++GO:0035904///aorta development+++GO:0042127///regulation of cell proliferation+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0044782///cilium organization+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050982///detection of mechanical stimulus+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051262///protein tetramerization+++GO:0051289///protein homotetramerization+++GO:0051290///protein heterotetramerization+++GO:0051726///regulation of cell cycle+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060674///placenta blood vessel development+++GO:0061333///renal tubule morphogenesis+++GO:0061441///renal artery morphogenesis+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071320///cellular response to cAMP+++GO:0071464///cellular response to hydrostatic pressure+++GO:0071470///cellular response to osmotic stress+++GO:0071498///cellular response to fluid shear stress+++GO:0071805///potassium ion transmembrane transport+++GO:0071910///determination of liver left/right asymmetry+++GO:0072075///metanephric mesenchyme development+++GO:0072164///mesonephric tubule development+++GO:0072177///mesonephric duct development+++GO:0072208///metanephric smooth muscle tissue development+++GO:0072214///metanephric cortex development+++GO:0072218///metanephric ascending thin limb development+++GO:0072219///metanephric cortical collecting duct development+++GO:0072235///metanephric distal tubule development+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0090279///regulation of calcium ion import+++GO:0098662///inorganic cation transmembrane transport+++GO:0198738///cell-cell signaling by wnt+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 18766 18766 'Pkdrej' mRNA 1 5 3 0.01 0.04 0.02 0.01 0.06 0.11 0.023333333 0.06 1 9 16 3 8.666666667 0.25214676 1.53256009 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0060046///regulation of acrosome reaction+++GO:0070588///calcium ion transmembrane transport 18767 18767 'Pkia' mRNA 420 446 435 5.87 6.25 6.4 4.56 3.4 4.54 6.173333333 4.166666667 364 274 360 433.6666667 332.6666667 0.008527988 -0.396746553 05034///Alcoholism GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0034236///protein kinase A catalytic subunit binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006469///negative regulation of protein kinase activity+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043086///negative regulation of catalytic activity+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 18768 18768 'Pkib' mRNA 63 47 69 2.93 1.75 3.67 19.15 19.69 17.74 2.783333333 18.86 443 461 418 59.66666667 440.6666667 9.11E-52 2.869797866 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0004862///cAMP-dependent protein kinase inhibitor activity GO:0006469///negative regulation of protein kinase activity+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:1904355///positive regulation of telomere capping+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 18769 18769 'Pkig' mRNA 3354 3250 3032 198.86 190.67 191.04 108.45 112.27 105.86 193.5233333 108.86 2099 2111 1977 3212 2062.333333 1.11E-23 -0.649839589 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0004862///cAMP-dependent protein kinase inhibitor activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006469///negative regulation of protein kinase activity+++GO:0007165///signal transduction+++GO:0042308///negative regulation of protein import into nucleus+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 18770 18770 'Pklr' mRNA 0 3 0 0 0.05 0 0 0.02 0 0.016666667 0.006666667 0 1 0 1 0.333333333 0.753543289 -1.448551084 00010///Glycolysis / Gluconeogenesis+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04910///Insulin signaling pathway+++04930///Type II diabetes mellitus+++04932///Non-alcoholic fatty liver disease+++04950///Maturity onset diabetes of the young GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004743///pyruvate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030955///potassium ion binding+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0005975///carbohydrate metabolic process+++GO:0006096///glycolytic process+++GO:0006754///ATP biosynthetic process+++GO:0007584///response to nutrient+++GO:0008152///metabolic process+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0010038///response to metal ion+++GO:0010226///response to lithium ion+++GO:0016310///phosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0033198///response to ATP+++GO:0042866///pyruvate biosynthetic process+++GO:0051591///response to cAMP+++GO:0051707///response to other organism+++GO:0071872///cellular response to epinephrine stimulus 18771 18771 'Pknox1' mRNA 484 521 452 6.06 6.45 6 5.6 5.81 5.1 6.17 5.503333333 511 520 456 485.6666667 495.6666667 0.901363997 0.019470422 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001525///angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030097///hemopoiesis+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18772 18772 'Pkp1' mRNA 344 397 325 3.95 4.48 3.96 2.3 2.34 2.9 4.13 2.513333333 231 229 282 355.3333333 247.3333333 8.88E-04 -0.531450004 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:1990124///messenger ribonucleoprotein complex GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0045296///cadherin binding GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0045110///intermediate filament bundle assembly+++GO:0098609///cell-cell adhesion+++GO:1902373///negative regulation of mRNA catabolic process 18777 18777 'Lypla1' mRNA 1239 1406 1337 27.6 30.85 31.57 35.85 34.08 33.49 30.00666667 34.47333333 1850 1719 1673 1327.333333 1747.333333 5.69E-06 0.383572911 00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0008970///phospholipase A1 activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0016042///lipid catabolic process+++GO:0042997///negative regulation of Golgi to plasma membrane protein transport 18778 18778 'Pla2g1b' mRNA 0 0 1 0 0 0.19 0 0 0.1 0.063333333 0.033333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0030141///secretory granule "GO:0004623///phospholipase A2 activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0032052///bile acid binding+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0002227///innate immune response in mucosa+++GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0019731///antibacterial humoral response+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050482///arachidonic acid secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1904635///positive regulation of glomerular visceral epithelial cell apoptotic process 18779 18779 'Pla2r1' mRNA 25 27 26 0.21 0.2 0.22 0.19 0.25 0.22 0.21 0.22 29 34 30 26 31 0.682374322 0.242973319 04145///Phagosome+++05152///Tuberculosis GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0043274///phospholipase binding "GO:0001819///positive regulation of cytokine production+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0072593///reactive oxygen species metabolic process+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0090399///replicative senescence+++GO:0090403///oxidative stress-induced premature senescence+++GO:1900138///negative regulation of phospholipase A2 activity+++GO:1900139///negative regulation of arachidonic acid secretion+++GO:1904635///positive regulation of glomerular visceral epithelial cell apoptotic process" 18781 18781 'Pla2g2c' mRNA 33 31 28 1.19 1.1 1.07 0.35 0.42 0.29 1.12 0.353333333 11 13 9 30.66666667 11 0.008539934 -1.488223505 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005575///cellular_component+++GO:0005576///extracellular region "GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0050482///arachidonic acid secretion 18782 18782 'Pla2g2d' mRNA 66.03 53.21 48.89 1.72 1.36 1.33 1.05 1.5 0.9 1.47 1.15 48 65.35 39.34 56.04333333 50.89666667 0.767329966 -0.142392166 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" "GO:0002361///CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0002864///regulation of acute inflammatory response to antigenic stimulus+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006954///inflammatory response+++GO:0016042///lipid catabolic process+++GO:0042130///negative regulation of T cell proliferation+++GO:0046337///phosphatidylethanolamine metabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0050482///arachidonic acid secretion+++GO:0050868///negative regulation of T cell activation" 18783 18783 'Pla2g4a' mRNA 93 130 108 1.8 2.47 2.21 9.55 9.59 9.56 2.16 9.566666667 569 558 552 110.3333333 559.6666667 9.01E-52 2.331936864 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04217///Necroptosis+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++05231///Choline metabolism in cancer GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042588///zymogen granule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0008374///O-acyltransferase activity+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0016787///hydrolase activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035035///histone acetyltransferase binding+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:1902387///ceramide 1-phosphate binding" GO:0001516///prostaglandin biosynthetic process+++GO:0001542///ovulation from ovarian follicle+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006071///glycerol metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006640///monoacylglycerol biosynthetic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006663///platelet activating factor biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009395///phospholipid catabolic process+++GO:0010033///response to organic substance+++GO:0010572///positive regulation of platelet activation+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0031340///positive regulation of vesicle fusion+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0034478///phosphatidylglycerol catabolic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0042127///regulation of cell proliferation+++GO:0043032///positive regulation of macrophage activation+++GO:0043065///positive regulation of apoptotic process+++GO:0043129///surfactant homeostasis+++GO:0046456///icosanoid biosynthetic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0046697///decidualization+++GO:0050482///arachidonic acid secretion+++GO:0050729///positive regulation of inflammatory response+++GO:0051592///response to calcium ion+++GO:0071236///cellular response to antibiotic 18784 18784 'Pla2g5' mRNA 2830 3030 2696 81.61 86.09 82.52 26.65 27.7 26.67 83.40666667 27.00666667 1065 1078 1030 2852 1057.666667 8.88E-95 -1.441395224 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0032010///phagolysosome+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome "GO:0004623///phospholipase A2 activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006663///platelet activating factor biosynthetic process+++GO:0006909///phagocytosis+++GO:0009395///phospholipid catabolic process+++GO:0010518///positive regulation of phospholipase activity+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0016042///lipid catabolic process+++GO:0019370///leukotriene biosynthetic process+++GO:0034097///response to cytokine+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034638///phosphatidylcholine catabolic process+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0043030///regulation of macrophage activation+++GO:0050482///arachidonic acid secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0051591///response to cAMP+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090265///positive regulation of immune complex clearance by monocytes and macrophages+++GO:0090385///phagosome-lysosome fusion+++GO:1903028///positive regulation of opsonization+++GO:1905036///positive regulation of antifungal innate immune response+++GO:1905164///positive regulation of phagosome maturation 18786 18786 'Plaa' mRNA 727.97 755.98 760 10.17 10.56 10.89 14.37 13.1 14.7 10.54 14.05666667 1092 1027 1095 747.9833333 1071.333333 7.50E-08 0.506457277 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0070062///extracellular exosome GO:0005515///protein binding+++GO:0016005///phospholipase A2 activator activity+++GO:0043130///ubiquitin binding GO:0006693///prostaglandin metabolic process+++GO:0006954///inflammatory response+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010992///ubiquitin recycling+++GO:0016236///macroautophagy+++GO:0032430///positive regulation of phospholipase A2 activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:1900045///negative regulation of protein K63-linked ubiquitination+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:1903861///positive regulation of dendrite extension+++GO:2001224///positive regulation of neuron migration 18788 18788 'Serpinb2' mRNA 5 0 4 0.14 0 0.12 2.42 1.99 2.43 0.086666667 2.28 97 78 94 3 89.66666667 3.53E-16 4.885395502 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0042060///wound healing+++GO:0043066///negative regulation of apoptotic process 18789 18789 'Papola' mRNA 2375 2485 2273 27.81 28.86 29.24 30.87 30.3 29.87 28.63666667 30.34666667 2955 2815 2789 2377.666667 2853 8.81E-05 0.251704929 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0031440///regulation of mRNA 3'-end processing+++GO:0043631///RNA polyadenylation 18791 18791 'Plat' mRNA 6287 6539 6385 137.86 140.97 148.54 110.69 119.85 110.3 142.4566667 113.6133333 5810 6130 5602 6403.666667 5847.333333 0.037386752 -0.143080244 04371///Apelin signaling pathway+++04610///Complement and coagulation cascades+++05202///Transcriptional misregulation in cancer+++05215///Prostate cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098992///neuronal dense core vesicle+++GO:0099544///perisynaptic space GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0051219///phosphoprotein binding "GO:0001666///response to hypoxia+++GO:0006508///proteolysis+++GO:0014909///smooth muscle cell migration+++GO:0031639///plasminogen activation+++GO:0035249///synaptic transmission, glutamatergic+++GO:0045861///negative regulation of proteolysis+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0060279///positive regulation of ovulation+++GO:0060468///prevention of polyspermy+++GO:0099183///trans-synaptic signaling by BDNF, modulating synaptic transmission" 18792 18792 'Plau' mRNA 12 9 3 0.29 0.21 0.08 9.82 5.92 9.24 0.193333333 8.326666667 472 278 430 8 393.3333333 9.91E-54 5.608929519 04064///NF-kappa B signaling pathway+++04610///Complement and coagulation cascades+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05215///Prostate cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0016020///membrane GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016301///kinase activity+++GO:0016787///hydrolase activity GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006508///proteolysis+++GO:0008284///positive regulation of cell proliferation+++GO:0010469///regulation of signaling receptor activity+++GO:0014909///smooth muscle cell migration+++GO:0014910///regulation of smooth muscle cell migration+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0031639///plasminogen activation+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042730///fibrinolysis+++GO:0043403///skeletal muscle tissue regeneration+++GO:0060279///positive regulation of ovulation+++GO:0070997///neuron death+++GO:2000097///regulation of smooth muscle cell-matrix adhesion+++GO:2000345///regulation of hepatocyte proliferation+++GO:2000379///positive regulation of reactive oxygen species metabolic process 18793 18793 'Plaur' mRNA 51 36 60 2 1.39 2.53 32.59 34.46 33.64 1.973333333 33.56333333 948 979 949 49 958.6666667 1.98E-144 4.276157306 04610///Complement and coagulation cascades+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030377///urokinase plasminogen activator receptor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0030162///regulation of proteolysis+++GO:0034112///positive regulation of homotypic cell-cell adhesion+++GO:0038195///urokinase plasminogen activator signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0048762///mesenchymal cell differentiation+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 18795 18795 'Plcb1' mRNA 350.43 388.53 340.4 2.55 2.75 2.58 1.57 1.37 1.68 2.626666667 1.54 265.84 224 269.61 359.7866667 253.15 5.92E-04 -0.519400992 "00562///Inositol phosphate metabolism+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05142///Chagas disease+++05143///African trypanosomiasis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse "GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005521///lamin binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding" "GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001556///oocyte maturation+++GO:0006397///mRNA processing+++GO:0006629///lipid metabolic process+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007420///brain development+++GO:0007613///memory+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008286///insulin receptor signaling pathway+++GO:0016042///lipid catabolic process+++GO:0021987///cerebral cortex development+++GO:0030218///erythrocyte differentiation+++GO:0030225///macrophage differentiation+++GO:0031161///phosphatidylinositol catabolic process+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032957///inositol trisphosphate metabolic process+++GO:0034284///response to monosaccharide+++GO:0035556///intracellular signal transduction+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0040019///positive regulation of embryonic development+++GO:0043434///response to peptide hormone+++GO:0045444///fat cell differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048639///positive regulation of developmental growth+++GO:0050790///regulation of catalytic activity+++GO:0051726///regulation of cell cycle+++GO:0060466///activation of meiosis involved in egg activation+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0080154///regulation of fertilization+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:0099178///regulation of retrograde trans-synaptic signaling by endocanabinoid+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1902618///cellular response to fluoride+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1904117///cellular response to vasopressin+++GO:1904637///cellular response to ionomycin+++GO:1905631///cellular response to glyceraldehyde+++GO:2000344///positive regulation of acrosome reaction+++GO:2000438///negative regulation of monocyte extravasation+++GO:2000560///positive regulation of CD24 biosynthetic process" 18796 18796 'Plcb2' mRNA 15 32 16 0.28 0.57 0.39 2.64 2.29 2.35 0.413333333 2.426666667 210 165 175 21 183.3333333 1.74E-24 3.11782175 "00562///Inositol phosphate metabolism+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05142///Chagas disease+++05143///African trypanosomiasis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050913///sensory perception of bitter taste 18797 18797 'Plcb3' mRNA 1399 1420 1009 17.68 17.65 13.55 16.51 21.15 20.27 16.29333333 19.31 1501 1880 1788 1276 1723 2.57E-04 0.430900182 "00562///Inositol phosphate metabolism+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05142///Chagas disease+++05143///African trypanosomiasis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0099524///postsynaptic cytosol GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity GO:0003073///regulation of systemic arterial blood pressure+++GO:0006629///lipid metabolic process+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0016042///lipid catabolic process+++GO:0031161///phosphatidylinositol catabolic process+++GO:0032957///inositol trisphosphate metabolic process+++GO:0035556///intracellular signal transduction+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling 18798 18798 'Plcb4' mRNA 1206 1263 1093 11.29 11.83 10.8 5.13 4.63 5.1 11.30666667 4.953333333 617 542 597 1187.333333 585.3333333 2.51E-29 -1.030848376 "00562///Inositol phosphate metabolism+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++04742///Taste transduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05142///Chagas disease+++05143///African trypanosomiasis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005790///smooth endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0043267///negative regulation of potassium ion transport+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050804///modulation of chemical synaptic transmission 18799 18799 'Plcd1' mRNA 1433 1391 1372 29.89 28.56 30.36 30.24 26.81 29.38 29.60333333 28.81 1668 1444 1569 1398.666667 1560.333333 0.100830976 0.144766581 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0045121///membrane raft "GO:0001786///phosphatidylserine binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0032794///GTPase activating protein binding+++GO:0046872///metal ion binding+++GO:0070300///phosphatidic acid binding+++GO:0070679///inositol 1,4,5 trisphosphate binding+++GO:1901981///phosphatidylinositol phosphate binding" GO:0001525///angiogenesis+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010701///positive regulation of norepinephrine secretion+++GO:0016042///lipid catabolic process+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051592///response to calcium ion+++GO:0060716///labyrinthine layer blood vessel development+++GO:1900274///regulation of phospholipase C activity 18802 18802 'Plcd4' mRNA 1254 1311 1213 24.4 25.15 24.99 15.72 14.66 14.2 24.84666667 14.86 918 836 811 1259.333333 855 3.92E-11 -0.57058655 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0001965///G-protein alpha-subunit binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0007340///acrosome reaction+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050790///regulation of catalytic activity 18803 18803 'Plcg1' mRNA 913 859 621 11.06 10.23 7.98 6.45 7.81 7.26 9.756666667 7.173333333 613 725 668 797.6666667 668.6666667 0.065598603 -0.257671844 "00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05131///Shigellosis+++05135///Yersinia infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008180///COP9 signalosome+++GO:0030027///lamellipodium+++GO:0030136///clathrin-coated vesicle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0005158///insulin receptor binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0035254///glutamate receptor binding+++GO:0046872///metal ion binding+++GO:0050429///calcium-dependent phospholipase C activity+++GO:0051219///phosphoprotein binding GO:0001701///in utero embryonic development+++GO:0006629///lipid metabolic process+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0009306///protein secretion+++GO:0009395///phospholipid catabolic process+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016042///lipid catabolic process+++GO:0016477///cell migration+++GO:0019722///calcium-mediated signaling+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0046488///phosphatidylinositol metabolic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050852///T cell receptor signaling pathway+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1901339///regulation of store-operated calcium channel activity+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000353///positive regulation of endothelial cell apoptotic process 18805 18805 'Pld1' mRNA 436 485 436 4.64 5.07 4.94 5.37 5.09 5.69 4.883333333 5.383333333 582 542 600 452.3333333 574.6666667 0.005707161 0.334109594 "00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04912///GnRH signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer" GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030139///endocytic vesicle+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0031985///Golgi cisterna+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098981///cholinergic synapse GO:0003824///catalytic activity+++GO:0004630///phospholipase D activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0035091///phosphatidylinositol binding+++GO:0070290///N-acylphosphatidylethanolamine-specific phospholipase D activity GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0030335///positive regulation of cell migration+++GO:0032534///regulation of microvillus assembly+++GO:0043434///response to peptide hormone+++GO:0045727///positive regulation of translation+++GO:0048017///inositol lipid-mediated signaling+++GO:0048870///cell motility+++GO:0050830///defense response to Gram-positive bacterium+++GO:0098693///regulation of synaptic vesicle cycle 18806 18806 'Pld2' mRNA 707.08 763.57 451.03 10.66 11.12 7.3 5.62 7.3 7.41 9.693333333 6.776666667 418.14 545.98 548.05 640.56 504.0566667 0.051083963 -0.344934158 "00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04912///GnRH signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer" GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0031526///brush border membrane+++GO:0042383///sarcolemma GO:0003824///catalytic activity+++GO:0004630///phospholipase D activity+++GO:0005080///protein kinase C binding+++GO:0016787///hydrolase activity+++GO:0035091///phosphatidylinositol binding+++GO:0070290///N-acylphosphatidylethanolamine-specific phospholipase D activity GO:0001666///response to hypoxia+++GO:0002031///G protein-coupled receptor internalization+++GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0006898///receptor-mediated endocytosis+++GO:0009395///phospholipid catabolic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014070///response to organic cyclic compound+++GO:0016042///lipid catabolic process+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0042542///response to hydrogen peroxide+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043434///response to peptide hormone+++GO:0045785///positive regulation of cell adhesion+++GO:0048017///inositol lipid-mediated signaling+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048870///cell motility 18807 18807 'Pld3' mRNA 4365 4524 4232 106.87 109.27 110.04 178.42 179.79 182.12 108.7266667 180.11 8365 8237 8264 4373.666667 8288.666667 4.00E-70 0.910984 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0043202///lysosomal lumen GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004630///phospholipase D activity+++GO:0016787///hydrolase activity+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity GO:0002376///immune system process+++GO:0006259///DNA metabolic process+++GO:0006954///inflammatory response+++GO:0014902///myotube differentiation+++GO:0045087///innate immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1900015///regulation of cytokine production involved in inflammatory response 18810 18810 'Plec' mRNA 2786 2689 2930 9.69 9.18 10.8 16.55 15.53 15.92 9.89 16 5508 5053 5139 2801.666667 5233.333333 4.94E-36 0.886263279 GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005903///brush border+++GO:0005925///focal adhesion+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016528///sarcoplasm+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0043209///myelin sheath+++GO:0043292///contractile fiber+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0002162///dystroglycan binding+++GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008307///structural constituent of muscle+++GO:0030506///ankyrin binding+++GO:0043621///protein self-association+++GO:0047485///protein N-terminus binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0002522///leukocyte migration involved in immune response+++GO:0003334///keratinocyte development+++GO:0006469///negative regulation of protein kinase activity+++GO:0006997///nucleus organization+++GO:0007005///mitochondrion organization+++GO:0007015///actin filament organization+++GO:0007519///skeletal muscle tissue development+++GO:0007584///response to nutrient+++GO:0010467///gene expression+++GO:0010761///fibroblast migration+++GO:0010818///T cell chemotaxis+++GO:0014866///skeletal myofibril assembly+++GO:0016569///covalent chromatin modification+++GO:0019226///transmission of nerve impulse+++GO:0022011///myelination in peripheral nervous system+++GO:0022904///respiratory electron transport chain+++GO:0030036///actin cytoskeleton organization+++GO:0030216///keratinocyte differentiation+++GO:0031532///actin cytoskeleton reorganization+++GO:0031581///hemidesmosome assembly+++GO:0031668///cellular response to extracellular stimulus+++GO:0032094///response to food+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0034332///adherens junction organization+++GO:0034613///cellular protein localization+++GO:0035264///multicellular organism growth+++GO:0042060///wound healing+++GO:0043114///regulation of vascular permeability+++GO:0043588///skin development+++GO:0043933///protein-containing complex subunit organization+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045109///intermediate filament organization+++GO:0045214///sarcomere organization+++GO:0045445///myoblast differentiation+++GO:0048741///skeletal muscle fiber development+++GO:0048870///cell motility+++GO:0055013///cardiac muscle cell development+++GO:0061436///establishment of skin barrier+++GO:0070584///mitochondrion morphogenesis+++GO:0071260///cellular response to mechanical stimulus+++GO:0071464///cellular response to hydrostatic pressure+++GO:0071498///cellular response to fluid shear stress+++GO:0120193///tight junction organization+++GO:2000689///actomyosin contractile ring assembly actin filament organization+++GO:2000983///regulation of ATP citrate synthase activity 18813 18813 'Pa2g4' mRNA 1646 1694 1461 37.8 38.3 35.59 52.65 50.83 51.35 37.23 51.61 2637 2486 2490 1600.333333 2537.666667 1.53E-22 0.65520573 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0031625///ubiquitin protein ligase binding "GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0043066///negative regulation of apoptotic process+++GO:0045597///positive regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 18815 18815 'Plg' mRNA 13 5 1 0.26 0.1 0.02 0 0 0.02 0.126666667 0.006666667 0 0 1 6.333333333 0.333333333 0.034447659 -4.130033709 04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection+++05164///Influenza A GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0019897///extrinsic component of plasma membrane+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0034358///plasma lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0001968///fibronectin binding+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0034185///apolipoprotein binding+++GO:0051087///chaperone binding+++GO:1990405///protein antigen binding "GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0016525///negative regulation of angiogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0042246///tissue regeneration+++GO:0042730///fibrinolysis+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045445///myoblast differentiation+++GO:0046716///muscle cell cellular homeostasis+++GO:0048771///tissue remodeling+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0051702///interaction with symbiont+++GO:0051918///negative regulation of fibrinolysis+++GO:0051919///positive regulation of fibrinolysis+++GO:0060707///trophoblast giant cell differentiation+++GO:0060716///labyrinthine layer blood vessel development+++GO:0071674///mononuclear cell migration+++GO:0099183///trans-synaptic signaling by BDNF, modulating synaptic transmission" 18817 18817 'Plk1' mRNA 63 81 81 1.6 2.03 2.19 11.44 10.45 9.92 1.94 10.60333333 517 461 434 75 470.6666667 3.60E-51 2.635633602 04068///FoxO signaling pathway+++04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000795///synaptonemal complex+++GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0034451///centriolar satellite+++GO:0051233///spindle midzone+++GO:0097431///mitotic spindle pole" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0010997///anaphase-promoting complex binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000132///establishment of mitotic spindle orientation+++GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0001578///microtubule bundle formation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007098///centrosome cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0016310///phosphorylation+++GO:0016321///female meiosis chromosome segregation+++GO:0016567///protein ubiquitination+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031648///protein destabilization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032465///regulation of cytokinesis+++GO:0033365///protein localization to organelle+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0043066///negative regulation of apoptotic process+++GO:0043393///regulation of protein binding+++GO:0045143///homologous chromosome segregation+++GO:0045184///establishment of protein localization+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045862///positive regulation of proteolysis+++GO:0051081///nuclear envelope disassembly+++GO:0051301///cell division+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0070194///synaptonemal complex disassembly+++GO:0071168///protein localization to chromatin+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0090435///protein localization to nuclear envelope+++GO:1901673///regulation of mitotic spindle assembly+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:1904776///regulation of protein localization to cell cortex 18821 18821 'Pln' mRNA 99 125 129 2.36 2.91 3.19 0.89 0.95 1.07 2.82 0.97 43 45 53 117.6666667 47 3.30E-06 -1.338379876 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031966///mitochondrial membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0090534///calcium ion-transporting ATPase complex GO:0005515///protein binding+++GO:0042030///ATPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0002026///regulation of the force of heart contraction+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007219///Notch signaling pathway+++GO:0008016///regulation of heart contraction+++GO:0010043///response to zinc ion+++GO:0010459///negative regulation of heart rate+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0032780///negative regulation of ATPase activity+++GO:0032868///response to insulin+++GO:0033574///response to testosterone+++GO:0043086///negative regulation of catalytic activity+++GO:0045822///negative regulation of heart contraction+++GO:0048738///cardiac muscle tissue development+++GO:0051924///regulation of calcium ion transport+++GO:0051926///negative regulation of calcium ion transport+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086023///adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:0086092///regulation of the force of heart contraction by cardiac conduction+++GO:0090279///regulation of calcium ion import+++GO:1901020///negative regulation of calcium ion transmembrane transporter activity+++GO:1901077///regulation of relaxation of muscle+++GO:1901877///negative regulation of calcium ion binding+++GO:1901894///regulation of calcium-transporting ATPase activity+++GO:1901895///negative regulation of calcium-transporting ATPase activity+++GO:1902081///negative regulation of calcium ion import into sarcoplasmic reticulum 18822 18822 'Plod1' mRNA 3407 3575 3620 57.24 59.09 64.51 64 65.02 64.43 60.28 64.48333333 4384 4350 4274 3534 4336 3.77E-05 0.281686137 00310///Lysine degradation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:1902494///catalytic complex "GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008475///procollagen-lysine 5-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001666///response to hypoxia+++GO:0008544///epidermis development+++GO:0017185///peptidyl-lysine hydroxylation 18823 18823 'Plp1' mRNA 10053 10936 9783 161.61 173.07 166.75 81.21 80.04 82.5 167.1433333 81.25 5788 5573 5700 10257.33333 5687 1.28E-62 -0.86177759 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034683///integrin alphav-beta3 complex+++GO:0043209///myelin sheath GO:0005515///protein binding+++GO:0019911///structural constituent of myelin sheath+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006954///inflammatory response+++GO:0008366///axon ensheathment+++GO:0010001///glial cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0014002///astrocyte development+++GO:0022010///central nervous system myelination+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0042552///myelination+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0048469///cell maturation+++GO:0061564///axon development+++GO:0098990///AMPA selective glutamate receptor signaling pathway+++GO:1904427///positive regulation of calcium ion transmembrane transport 18824 18824 'Plp2' mRNA 678.4 711.69 710.76 36.28 37.59 40.33 94.48 89.95 89.74 38.06666667 91.39 2027.2 1882.1 1861.76 700.2833333 1923.686667 1.16E-68 1.445665966 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019956///chemokine binding 18826 18826 'Lcp1' mRNA 355 337 376 5.28 4.95 5.96 84.18 87.82 85.88 5.396666667 85.96 6411 6554 6368 356 6444.333333 0 4.16544989 GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0001891///phagocytic cup+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0032432///actin filament bundle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051020///GTPase binding GO:0002286///T cell activation involved in immune response+++GO:0009611///response to wounding+++GO:0010737///protein kinase A signaling+++GO:0016477///cell migration+++GO:0022617///extracellular matrix disassembly+++GO:0031100///animal organ regeneration+++GO:0033157///regulation of intracellular protein transport+++GO:0051017///actin filament bundle assembly+++GO:0051639///actin filament network formation+++GO:0071803///positive regulation of podosome assembly 18828 18828 'Plscr2' mRNA 1882.82 2049.75 1923.8 56.96 61.34 61.73 83.71 90.19 86.57 60.01 86.82333333 3175.59 3349.4 3190.28 1952.123333 3238.423333 8.17E-25 0.71947483 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix "GO:0000287///magnesium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001618///virus receptor activity+++GO:0004518///nuclease activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0017124///SH3 domain binding+++GO:0017128///phospholipid scramblase activity+++GO:0019899///enzyme binding+++GO:0032791///lead ion binding+++GO:0042609///CD4 receptor binding+++GO:0045340///mercury ion binding+++GO:0046872///metal ion binding" GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0010288///response to lead ion+++GO:0010628///positive regulation of gene expression+++GO:0017121///phospholipid scrambling+++GO:0033003///regulation of mast cell activation+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045089///positive regulation of innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046718///viral entry into host cell+++GO:0050765///negative regulation of phagocytosis+++GO:0051607///defense response to virus+++GO:0060368///regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905820///positive regulation of chromosome separation+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 18829 18829 'Ccl21a' mRNA 201.86 203.33 222.16 15.45 15.41 18.04 4.82 4.86 3.74 16.3 4.473333333 72.18 70.89 54.08 209.1166667 65.71666667 5.21E-14 -1.690537553 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001768///establishment of T cell polarity+++GO:0001771///immunological synapse formation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002407///dendritic cell chemotaxis+++GO:0002548///monocyte chemotaxis+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010560///positive regulation of glycoprotein biosynthetic process+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0030593///neutrophil chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031295///T cell costimulation+++GO:0031529///ruffle organization+++GO:0031640///killing of cells of other organism+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0034695///response to prostaglandin E+++GO:0035759///mesangial cell-matrix adhesion+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048469///cell maturation+++GO:0048535///lymph node development+++GO:0050921///positive regulation of chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051491///positive regulation of filopodium assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090630///activation of GTPase activity+++GO:0097026///dendritic cell dendrite assembly+++GO:1903237///negative regulation of leukocyte tethering or rolling+++GO:1990869///cellular response to chemokine+++GO:2000147///positive regulation of cell motility+++GO:2000406///positive regulation of T cell migration+++GO:2000529///positive regulation of myeloid dendritic cell chemotaxis+++GO:2000548///negative regulation of dendritic cell dendrite assembly+++GO:2000669///negative regulation of dendritic cell apoptotic process 18830 18830 'Pltp' mRNA 3567.24 3529.4 3202.32 113.74 110.9 108.32 198.18 191.48 194.76 110.9866667 194.8066667 7142.4 6734.82 6795.56 3432.986667 6890.926667 5.18E-80 0.99457309 03320///PPAR signaling pathway+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0034364///high-density lipoprotein particle GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0008525///phosphatidylcholine transporter activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0019992///diacylglycerol binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0031210///phosphatidylcholine binding+++GO:0034189///very-low-density lipoprotein particle binding+++GO:0070300///phosphatidic acid binding+++GO:0097001///ceramide binding+++GO:0120014///intermembrane phospholipid transfer activity+++GO:0120017///intermembrane ceramide transfer activity+++GO:0120019///intermembrane phosphotidylcholine transfer activity+++GO:0120020///intermembrane cholesterol transfer activity+++GO:1901611///phosphatidylglycerol binding+++GO:1904121///phosphatidylethanolamine transporter activity+++GO:1990050///phosphatidic acid transporter activity GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0010189///vitamin E biosynthetic process+++GO:0010875///positive regulation of cholesterol efflux+++GO:0015914///phospholipid transport+++GO:0015918///sterol transport+++GO:0030317///flagellated sperm motility+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0035627///ceramide transport+++GO:0046836///glycolipid transport+++GO:0120009///intermembrane lipid transfer 18843 18843 'Bpifa1' mRNA 6 7 11 0.34 0.39 0.66 4.24 5.11 3.27 0.463333333 4.206666667 86 101 64 8 83.66666667 2.75E-13 3.370521431 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005902///microvillus GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0002376///immune system process+++GO:0002395///immune response in nasopharyngeal-associated lymphoid tissue+++GO:0019731///antibacterial humoral response+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050828///regulation of liquid surface tension+++GO:0050891///multicellular organismal water homeostasis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1900229///negative regulation of single-species biofilm formation in or on host organism+++GO:1902305///regulation of sodium ion transmembrane transport 18844 18844 'Plxna1' mRNA 1054 1083 926 6.12 6.19 5.71 9.34 8.62 9.27 6.006666667 9.076666667 1852 1670 1779 1021 1767 8.47E-24 0.781242966 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0014910///regulation of smooth muscle cell migration+++GO:0030334///regulation of cell migration+++GO:0043087///regulation of GTPase activity+++GO:0050772///positive regulation of axonogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097485///neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1990138///neuron projection extension 18845 18845 'Plxna2' mRNA 996 974 921 4.91 4.7 4.76 3.52 3.42 3.67 4.79 3.536666667 827 783 838 963.6666667 816 0.008099916 -0.251254303 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity+++GO:0042802///identical protein binding GO:0001756///somitogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0021915///neural tube development+++GO:0021935///cerebellar granule cell precursor tangential migration+++GO:0030334///regulation of cell migration+++GO:0043087///regulation of GTPase activity+++GO:0050772///positive regulation of axonogenesis+++GO:0051642///centrosome localization+++GO:0060037///pharyngeal system development+++GO:0060174///limb bud formation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 18846 18846 'Plxna3' mRNA 568 566 464 4.81 4.71 4.36 1.8 1.68 1.86 4.626666667 1.78 226 201 232 532.6666667 219.6666667 1.88E-21 -1.286615739 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017154///semaphorin receptor activity GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0021612///facial nerve structural organization+++GO:0021637///trigeminal nerve structural organization+++GO:0021766///hippocampus development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021860///pyramidal neuron development+++GO:0030334///regulation of cell migration+++GO:0043087///regulation of GTPase activity+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050772///positive regulation of axonogenesis+++GO:0050919///negative chemotaxis+++GO:0051495///positive regulation of cytoskeleton organization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097485///neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1990138///neuron projection extension 18854 18854 'Pml' mRNA 747 820 800 8.35 8.91 9.7 15.54 13.43 14.37 8.986666667 14.44666667 1591 1351 1405 789 1449 8.23E-21 0.862929412 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0031965///nuclear membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane" GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0032183///SUMO binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050897///cobalt ion binding+++GO:0140037///sumo-dependent protein binding "GO:0001666///response to hypoxia+++GO:0001932///regulation of protein phosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006605///protein targeting+++GO:0006606///protein import into nucleus+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007569///cell aging+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009411///response to UV+++GO:0010332///response to gamma radiation+++GO:0010522///regulation of calcium ion transport into cytosol+++GO:0010761///fibroblast migration+++GO:0016032///viral process+++GO:0016525///negative regulation of angiogenesis+++GO:0030099///myeloid cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030308///negative regulation of cell growth+++GO:0030578///PML body organization+++GO:0031065///positive regulation of histone deacetylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032922///circadian regulation of gene expression+++GO:0032938///negative regulation of translation in response to oxidative stress+++GO:0034097///response to cytokine+++GO:0042752///regulation of circadian rhythm+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045165///cell fate commitment+++GO:0045343///regulation of MHC class I biosynthetic process+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0051457///maintenance of protein location in nucleus+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0051974///negative regulation of telomerase activity+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071353///cellular response to interleukin-4+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090398///cellular senescence+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1902187///negative regulation of viral release from host cell+++GO:1904816///positive regulation of protein localization to chromosome, telomeric region+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000779///regulation of double-strand break repair+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 18857 18857 'Pmp2' mRNA 105 105 144 4.62 4.56 6.72 58.23 63.69 61.39 5.3 61.10333333 1520 1622 1550 118 1564 1.22E-177 3.713251651 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043209///myelin sheath GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding GO:0015908///fatty acid transport+++GO:0061024///membrane organization 18858 18858 'Pmp22' mRNA 32723 33495 31809 1028.34 1037.12 1060.51 697.16 686.62 699.22 1041.99 694.3333333 25540 24533 24798 32675.66667 24957 7.87E-19 -0.400700764 GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043218///compact myelin+++GO:0043256///laminin complex+++GO:0048471///perinuclear region of cytoplasm GO:0003774///motor activity+++GO:0005515///protein binding "GO:0006914///autophagy+++GO:0006955///immune response+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007155///cell adhesion+++GO:0007422///peripheral nervous system development+++GO:0007618///mating+++GO:0007628///adult walking behavior+++GO:0008203///cholesterol metabolic process+++GO:0008219///cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0009617///response to bacterium+++GO:0010259///multicellular organism aging+++GO:0010468///regulation of gene expression+++GO:0010498///proteasomal protein catabolic process+++GO:0010624///regulation of Schwann cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010761///fibroblast migration+++GO:0010977///negative regulation of neuron projection development+++GO:0014037///Schwann cell differentiation+++GO:0014044///Schwann cell development+++GO:0019226///transmission of nerve impulse+++GO:0019227///neuronal action potential propagation+++GO:0019228///neuronal action potential+++GO:0022011///myelination in peripheral nervous system+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030913///paranodal junction assembly+++GO:0031579///membrane raft organization+++GO:0032060///bleb assembly+++GO:0032288///myelin assembly+++GO:0034350///regulation of glial cell apoptotic process+++GO:0034605///cellular response to heat+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035264///multicellular organism growth+++GO:0036135///Schwann cell migration+++GO:0042063///gliogenesis+++GO:0042552///myelination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044255///cellular lipid metabolic process+++GO:0045161///neuronal ion channel clustering+++GO:0048747///muscle fiber development+++GO:0048936///peripheral nervous system neuron axonogenesis+++GO:0050727///regulation of inflammatory response+++GO:0050905///neuromuscular process+++GO:0051146///striated muscle cell differentiation+++GO:0051641///cellular localization+++GO:0051726///regulation of cell cycle+++GO:0055001///muscle cell development+++GO:0060005///vestibular reflex+++GO:0061564///axon development+++GO:0061744///motor behavior+++GO:0070842///aggresome assembly+++GO:0071711///basement membrane organization+++GO:0071900///regulation of protein serine/threonine kinase activity+++GO:0098529///neuromuscular junction development, skeletal muscle fiber+++GO:2001233///regulation of apoptotic signaling pathway" 18861 18861 'Pms2' mRNA 918 869 919 8.96 8.45 9.65 3.37 3.41 3.58 9.02 3.453333333 303 298 303 902 301.3333333 3.45E-46 -1.595192555 03430///Mismatch repair+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032300///mismatch repair complex+++GO:0032389///MutLalpha complex+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0030983///mismatched DNA binding+++GO:0032138///single base insertion or deletion binding+++GO:0032407///MutSalpha complex binding GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0042493///response to drug+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 18933 18933 'Prrx1' mRNA 212 201 172 2.41 2.31 2.12 3.71 3.06 3.37 2.28 3.38 369 305 330 195 334.6666667 1.33E-06 0.768803662 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0071837///HMG box domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030326///embryonic limb morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048664///neuron fate determination+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048844///artery morphogenesis+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0070570///regulation of neuron projection regeneration+++GO:0097150///neuronal stem cell population maintenance+++GO:0100026///positive regulation of DNA repair by transcription from RNA polymerase II promoter" 18938 18938 'Ppp1r14b' mRNA 158 112 90 11.24 7.88 6.79 12.85 17.07 14.2 8.636666667 14.70666667 207 268 221 120 232 3.10E-05 0.947806602 GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0019212///phosphatase inhibitor activity+++GO:0019888///protein phosphatase regulator activity GO:0042325///regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0050790///regulation of catalytic activity 18949 18949 'Pnn' mRNA 2445 2457 2173 38.35 37.92 36.15 31.57 30.42 30.65 37.47333333 30.88 2316 2180 2178 2358.333333 2224.666667 0.204795551 -0.094428647 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0035145///exon-exon junction complex+++GO:0071013///catalytic step 2 spliceosome GO:0003677///DNA binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0098609///cell-cell adhesion 18950 18950 'Pnp' mRNA 841.69 895 896.31 15.74 16.47 17.78 57.44 57.6 55.86 16.66333333 56.96666667 3533.64 3460.79 3326.96 877.6666667 3440.463333 1.99E-155 1.958185397 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001882///nucleoside binding+++GO:0002060///purine nucleobase binding+++GO:0003824///catalytic activity+++GO:0004731///purine-nucleoside phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042301///phosphate ion binding+++GO:0042802///identical protein binding+++GO:0047975///guanosine phosphorylase activity" GO:0000255///allantoin metabolic process+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006148///inosine catabolic process+++GO:0006149///deoxyinosine catabolic process+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process+++GO:0006161///deoxyguanosine catabolic process+++GO:0006166///purine ribonucleoside salvage+++GO:0006183///GTP biosynthetic process+++GO:0006196///AMP catabolic process+++GO:0006202///GMP catabolic process to guanine+++GO:0006204///IMP catabolic process+++GO:0006738///nicotinamide riboside catabolic process+++GO:0006955///immune response+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008637///apoptotic mitochondrial changes+++GO:0009116///nucleoside metabolic process+++GO:0009165///nucleotide biosynthetic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010332///response to gamma radiation+++GO:0032263///GMP salvage+++GO:0032264///IMP salvage+++GO:0032743///positive regulation of interleukin-2 production+++GO:0034418///urate biosynthetic process+++GO:0042102///positive regulation of T cell proliferation+++GO:0042278///purine nucleoside metabolic process+++GO:0042493///response to drug+++GO:0043101///purine-containing compound salvage+++GO:0044209///AMP salvage+++GO:0045579///positive regulation of B cell differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0046038///GMP catabolic process+++GO:0046055///dGMP catabolic process+++GO:0046059///dAMP catabolic process+++GO:0046070///dGTP metabolic process+++GO:0046115///guanosine catabolic process+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0070233///negative regulation of T cell apoptotic process 18951 18951 'Septin5' mRNA 206.54 228.17 114.36 5.49 5.98 3.23 2.88 3.42 2.74 4.9 3.013333333 124.49 144.57 114.69 183.0233333 127.9166667 0.049565723 -0.518447888 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005940///septin ring+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0031105///septin complex+++GO:0032153///cell division site+++GO:0032154///cleavage furrow+++GO:0043195///terminal bouton+++GO:0043679///axon terminus+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019905///syntaxin binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0017157///regulation of exocytosis+++GO:0030534///adult behavior+++GO:0034613///cellular protein localization+++GO:0035176///social behavior+++GO:0045921///positive regulation of exocytosis+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0099148///regulation of synaptic vesicle docking 18952 18952 'Septin4' mRNA 688 648 681 28.5 26.57 30.55 20.48 23.99 20.91 28.54 21.79333333 543 620 537 672.3333333 566.6666667 0.038764135 -0.258712895 04210///Apoptosis+++04215///Apoptosis - multiple species GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005940///septin ring+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0030133///transport vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031105///septin complex+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0032153///cell division site+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0097227///sperm annulus GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0060090///molecular adaptor activity GO:0001764///neuron migration+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007420///brain development+++GO:0008150///biological_process+++GO:0017157///regulation of exocytosis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0030382///sperm mitochondrion organization+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034613///cellular protein localization+++GO:0043065///positive regulation of apoptotic process+++GO:0048240///sperm capacitation+++GO:0048515///spermatid differentiation+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 18968 18968 'Pola1' mRNA 189 218 192 1.88 2.11 2.02 2.67 2.28 2.61 2.003333333 2.52 310 259 293 199.6666667 287.3333333 0.002312215 0.513134444 03030///DNA replication GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005658///alpha DNA polymerase:primase complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0017076///purine nucleotide binding+++GO:0019103///pyrimidine nucleotide binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000731///DNA synthesis involved in DNA repair+++GO:0006260///DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:0006270///DNA replication initiation+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0006272///leading strand elongation+++GO:0006273///lagging strand elongation+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0032479///regulation of type I interferon production+++GO:0071897///DNA biosynthetic process+++GO:1902975///mitotic DNA replication initiation+++GO:1904161///DNA synthesis involved in UV-damage excision repair" 18969 18969 'Pola2' mRNA 282.13 279.26 283.54 6.45 6.28 6.9 12.05 11.07 9.63 6.543333333 10.91666667 605.33 544.26 465.74 281.6433333 538.4433333 2.51E-11 0.921554837 03030///DNA replication GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005658///alpha DNA polymerase:primase complex+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding "GO:0006260///DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:0006270///DNA replication initiation+++GO:0006606///protein import into nucleus+++GO:0071897///DNA biosynthetic process" 18970 18970 'Polb' mRNA 1355.52 1268.22 1326.44 50.12 49.56 52.67 51.16 47.66 50.45 50.78333333 49.75666667 1973.88 1819.87 1858.11 1316.726667 1883.953333 2.10E-10 0.503213424 03410///Base excision repair+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0008017///microtubule binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0034061///DNA polymerase activity+++GO:0046872///metal ion binding "GO:0001701///in utero embryonic development+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006287///base-excision repair, gap-filling+++GO:0006290///pyrimidine dimer repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007435///salivary gland morphogenesis+++GO:0007568///aging+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010332///response to gamma radiation+++GO:0016445///somatic diversification of immunoglobulins+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0045471///response to ethanol+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0048872///homeostasis of number of cells+++GO:0051402///neuron apoptotic process+++GO:0055093///response to hyperoxia+++GO:0071707///immunoglobulin heavy chain V-D-J recombination+++GO:0071897///DNA biosynthetic process" 18971 18971 'Pold1' mRNA 460.02 478.87 438.33 6.82 7.02 6.82 5.98 7.72 7.03 6.886666667 6.91 534.16 666.3 599.36 459.0733333 599.94 0.004092155 0.377897128 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination "GO:0000109///nucleotide-excision repair complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0043625///delta DNA polymerase complex" "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000731///DNA synthesis involved in DNA repair+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006287///base-excision repair, gap-filling+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0034644///cellular response to UV+++GO:0045004///DNA replication proofreading+++GO:0055089///fatty acid homeostasis+++GO:0070987///error-free translesion synthesis+++GO:0071897///DNA biosynthetic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 18972 18972 'Pold2' mRNA 663 734 796 24.08 26.29 30.68 18.72 19.67 19.67 27.01666667 19.35333333 592 607 602 731 600.3333333 0.017100509 -0.299100673 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0042575///DNA polymerase complex+++GO:0043625///delta DNA polymerase complex GO:0003677///DNA binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0071897///DNA biosynthetic process 18973 18973 'Pole' mRNA 614 727 722 4.55 5.29 5.67 1.37 1.37 1.45 5.17 1.396666667 213 208 218 687.6666667 213 5.01E-37 -1.70474089 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0008622///epsilon DNA polymerase complex "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0006260///DNA replication+++GO:0006272///leading strand elongation+++GO:0006281///DNA repair+++GO:0006287///base-excision repair, gap-filling+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045004///DNA replication proofreading+++GO:0048568///embryonic organ development+++GO:0071897///DNA biosynthetic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 18974 18974 'Pole2' mRNA 20 22 17 0.67 0.73 0.61 2.76 2.95 2.73 0.67 2.813333333 94 97 89 19.66666667 93.33333333 1.18E-10 2.238103468 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008622///epsilon DNA polymerase complex+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0042276///error-prone translesion synthesis 18975 18975 'Polg' mRNA 1027.9 1067.01 854.92 13.12 13.22 11.18 8.43 10.99 9.94 12.50666667 9.786666667 862.41 1034.29 1025.91 983.2766667 974.2033333 0.891506457 -0.019193509 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005760///gamma DNA polymerase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0042645///mitochondrial nucleoid+++GO:0043195///terminal bouton GO:0002020///protease binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008408///3'-5' exonuclease activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity "GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006287///base-excision repair, gap-filling+++GO:0007568///aging+++GO:0009416///response to light stimulus+++GO:0010332///response to gamma radiation+++GO:0055093///response to hyperoxia+++GO:0071333///cellular response to glucose stimulus+++GO:0071897///DNA biosynthetic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 18976 18976 'Pomc' mRNA 46 32 33 2.91 2 2.22 2.59 2.27 2.46 2.376666667 2.44 48 40 44 37 44 0.631368257 0.238618579 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04920///Adipocytokine signaling pathway+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005782///peroxisomal matrix+++GO:0030141///secretory granule GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0070996///type 1 melanocortin receptor binding GO:0006091///generation of precursor metabolites and energy+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007267///cell-cell signaling+++GO:0008217///regulation of blood pressure+++GO:0019722///calcium-mediated signaling+++GO:0031640///killing of cells of other organism+++GO:0032098///regulation of appetite+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033059///cellular pigmentation+++GO:0035821///modification of morphology or physiology of other organism+++GO:0042593///glucose homeostasis+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070873///regulation of glycogen metabolic process+++GO:0070965///positive regulation of neutrophil mediated killing of fungus+++GO:1990680///response to melanocyte-stimulating hormone+++GO:2000852///regulation of corticosterone secretion 18983 18983 'Cnot7' mRNA 1502.57 1436.42 1484.81 31.27 29.29 32.82 22.97 23.79 23.92 31.12666667 23.56 1270.5 1284.19 1278.39 1474.6 1277.693333 0.011652354 -0.219287643 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004532///exoribonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0006417///regulation of translation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045070///positive regulation of viral genome replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" 18984 18984 'Por' mRNA 8019 8160 8055 176.72 177.02 188.48 107.77 110.61 108.32 180.74 108.9 5630 5639 5475 8078 5581.333333 4.91E-22 -0.545862322 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003958///NADPH-hemoprotein reductase activity+++GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0008941///nitric oxide dioxygenase activity+++GO:0009055///electron transfer activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0047726///iron-cytochrome-c reductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0007584///response to nutrient+++GO:0009437///carnitine metabolic process+++GO:0009725///response to hormone+++GO:0009812///flavonoid metabolic process+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0019395///fatty acid oxidation+++GO:0022900///electron transport chain+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032770///positive regulation of monooxygenase activity+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043602///nitrate catabolic process+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0046210///nitric oxide catabolic process+++GO:0060192///negative regulation of lipase activity+++GO:0070988///demethylation+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071548///response to dexamethasone+++GO:0090031///positive regulation of steroid hormone biosynthetic process+++GO:0090181///regulation of cholesterol metabolic process+++GO:0090346///cellular organofluorine metabolic process 18985 18985 'Pou2af1' mRNA 56 18 17 1.21 0.38 0.39 0.24 0.15 0.35 0.66 0.246666667 13 8 18 30.33333333 13 0.071384659 -1.225039889 GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding GO:0002314///germinal center B cell differentiation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0098586///cellular response to virus 18986 18986 'Pou2f1' mRNA 3749.81 3656.5 3267.78 5.53 5.34 5.16 3.29 2.72 3.12 5.343333333 3.043333333 2568.06 2060.61 2345.55 3558.03 2324.74 4.76E-17 -0.625492313 05168///Herpes simplex virus 1 infection+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression+++GO:0030910///olfactory placode formation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060235///lens induction in camera-type eye" 18987 18987 'Pou2f2' mRNA 64 57.15 54.98 0.85 0.83 0.8 3.1 3.34 2.87 0.826666667 3.103333333 250 245.92 230 58.71 241.9733333 3.21E-22 2.040005336 05168///Herpes simplex virus 1 infection+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002335///mature B cell differentiation+++GO:0002377///immunoglobulin production+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0098586///cellular response to virus" 18988 18988 'Pou2f3' mRNA 8 15 15 0.18 0.3 0.35 0.33 0.24 0.14 0.276666667 0.236666667 17 12 7 12.66666667 12 0.917128784 -0.098811414 05168///Herpes simplex virus 1 infection+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0042060///wound healing+++GO:0043922///negative regulation by host of viral transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18991 18991 'Pou3f1' mRNA 125 128 121 2.28 2.3 2.34 1.9 1.51 1.9 2.306666667 1.77 120 93 116 124.6666667 109.6666667 0.478173058 -0.197909533 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0008544///epidermis development+++GO:0010001///glial cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0014044///Schwann cell development+++GO:0022011///myelination in peripheral nervous system+++GO:0030216///keratinocyte differentiation+++GO:0030900///forebrain development+++GO:0042552///myelination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 18992 18992 'Pou3f2' mRNA 374 384 352 3.16 3.19 3.15 1.92 1.78 2.02 3.166666667 1.906666667 262 237 267 370 255.3333333 1.53E-04 -0.546411104 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0010629///negative regulation of gene expression+++GO:0014002///astrocyte development+++GO:0014044///Schwann cell development+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021869///forebrain ventricular zone progenitor cell division+++GO:0021979///hypothalamus cell differentiation+++GO:0021985///neurohypophysis development+++GO:0022011///myelination in peripheral nervous system+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0040018///positive regulation of multicellular organism growth+++GO:0045595///regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment+++GO:0048665///neuron fate specification+++GO:0048666///neuron development+++GO:0050770///regulation of axonogenesis+++GO:0071310///cellular response to organic substance" 18993 18993 'Pou3f3' mRNA 689 676 537 8.33 8.04 6.88 7.48 6.67 7.76 7.75 7.303333333 712 621 716 634 683 0.475666329 0.099136514 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0071837///HMG box domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007588///excretion+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021869///forebrain ventricular zone progenitor cell division+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048878///chemical homeostasis+++GO:0072218///metanephric ascending thin limb development+++GO:0072227///metanephric macula densa development+++GO:0072233///metanephric thick ascending limb development+++GO:0072236///metanephric loop of Henle development+++GO:0072240///metanephric DCT cell differentiation" 18994 18994 'Pou3f4' mRNA 879 888 743 9.95 9.89 8.92 12.23 10.13 11.01 9.586666667 11.12333333 1244 1006 1084 836.6666667 1111.333333 6.74E-05 0.399062834 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007605///sensory perception of sound+++GO:0021879///forebrain neuron differentiation+++GO:0048839///inner ear development+++GO:0090103///cochlea morphogenesis+++GO:2001054///negative regulation of mesenchymal cell apoptotic process" 18996 18996 'Pou4f1' mRNA 9 18 9 0.11 0.24 0.11 0.11 0.1 0.06 0.153333333 0.09 9 8 6 12 7.666666667 0.496863394 -0.650107574 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0051020///GTPase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001967///suckling behavior+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0021535///cell migration in hindbrain+++GO:0021559///trigeminal nerve development+++GO:0021953///central nervous system neuron differentiation+++GO:0021986///habenula development+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048665///neuron fate specification+++GO:0048880///sensory system development+++GO:0048934///peripheral nervous system neuron differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0050767///regulation of neurogenesis+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051355///proprioception involved in equilibrioception+++GO:0051726///regulation of cell cycle+++GO:0060384///innervation+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071345///cellular response to cytokine stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2001208///negative regulation of transcription elongation by RNA polymerase I" 18997 18997 'Pou4f2' mRNA 79 89 91 1.35 1.49 1.65 0.03 0.29 0.18 1.496666667 0.166666667 2 19 12 86.33333333 11 2.75E-10 -2.978246634 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0010468///regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032869///cellular response to insulin stimulus+++GO:0043068///positive regulation of programmed cell death+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045596///negative regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0048675///axon extension+++GO:0050885///neuromuscular process controlling balance+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0060041///retina development in camera-type eye+++GO:0071345///cellular response to cytokine stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071453///cellular response to oxygen levels+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090259///regulation of retinal ganglion cell axon guidance+++GO:1902870///negative regulation of amacrine cell differentiation+++GO:1904178///negative regulation of adipose tissue development+++GO:1990791///dorsal root ganglion development+++GO:2000679///positive regulation of transcription regulatory region DNA binding" 18998 18998 'Pou4f3' mRNA 968 1032 753 52.36 55.15 43.22 4.34 3.53 3.75 50.24333333 3.873333333 92 73 77 917.6666667 80.66666667 1.70E-118 -3.514927407 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007605///sensory perception of sound+++GO:0021562///vestibulocochlear nerve development+++GO:0030154///cell differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048675///axon extension+++GO:0048839///inner ear development+++GO:0050885///neuromuscular process controlling balance+++GO:0051402///neuron apoptotic process+++GO:0060113///inner ear receptor cell differentiation" 18999 18999 'Pou5f1' mRNA 1 1 1 0.06 0.06 0.07 0.11 0 0 0.063333333 0.036666667 2 0 0 1 0.666666667 0.863090843 -0.621404203 04550///Signaling pathways regulating pluripotency of stem cells GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019955///cytokine binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035198///miRNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0070974///POU domain binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001710///mesodermal cell fate commitment+++GO:0001711///endodermal cell fate commitment+++GO:0001712///ectodermal cell fate commitment+++GO:0001714///endodermal cell fate specification+++GO:0001824///blastocyst development+++GO:0001827///inner cell mass cell fate commitment+++GO:0001829///trophectodermal cell differentiation+++GO:0001832///blastocyst growth+++GO:0003130///BMP signaling pathway involved in heart induction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009786///regulation of asymmetric cell division+++GO:0010033///response to organic substance+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0030718///germ-line stem cell population maintenance+++GO:0032526///response to retinoic acid+++GO:0034097///response to cytokine+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0048863///stem cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060913///cardiac cell fate determination+++GO:1990830///cellular response to leukemia inhibitory factor" 19009 19009 'Pou6f1' mRNA 518 475 471 7.55 7.19 7.07 4.48 3.94 3.98 7.27 4.133333333 362 317 311 488 330 1.03E-05 -0.577068558 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0045202///synapse "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0098632///cell-cell adhesion mediator activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0035879///plasma membrane lactate transport+++GO:0070593///dendrite self-avoidance" 19011 19011 'Endou' mRNA 131 102 119 3.24 2.57 3.17 2.82 2.77 2.34 2.993333333 2.643333333 125 123 102 117.3333333 116.6666667 0.945906652 -0.022092508 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005044///scavenger receptor activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0030247///polysaccharide binding+++GO:0046872///metal ion binding "GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0007565///female pregnancy+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 19012 19012 'Plpp1' mRNA 1546 1723 1564.77 56.11 61.65 60.25 80.56 80.97 80.02 59.33666667 80.51666667 2549.85 2500.99 2450.58 1611.256667 2500.473333 1.07E-18 0.622518324 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00600///Sphingolipid metabolism+++04072///Phospholipase D signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04975///Fat digestion and absorption+++05231///Choline metabolism in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0045121///membrane raft GO:0000810///diacylglycerol diphosphate phosphatase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0042577///lipid phosphatase activity GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0006670///sphingosine metabolic process+++GO:0006672///ceramide metabolic process+++GO:0007165///signal transduction+++GO:0046839///phospholipid dephosphorylation 19013 19013 'Ppara' mRNA 165 139 146 1.17 0.98 1.1 0.85 0.6 0.78 1.083333333 0.743333333 138 96 122 150 118.6666667 0.156491042 -0.35263073 03320///PPAR signaling pathway+++04024///cAMP signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05160///Hepatitis C+++05207///Chemical carcinogenesis - receptor activation+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008144///drug binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019902///phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0038023///signaling receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051525///NFAT protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0097371///MDM2/MDM4 family protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0006006///glucose metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007507///heart development+++GO:0008544///epidermis development+++GO:0009267///cellular response to starvation+++GO:0009755///hormone-mediated signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010565///regulation of cellular ketone metabolic process+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010876///lipid localization+++GO:0010883///regulation of lipid storage+++GO:0010887///negative regulation of cholesterol storage+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0014070///response to organic cyclic compound+++GO:0019216///regulation of lipid metabolic process+++GO:0019217///regulation of fatty acid metabolic process+++GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0032099///negative regulation of appetite+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0033993///response to lipid+++GO:0035095///behavioral response to nicotine+++GO:0042060///wound healing+++GO:0042157///lipoprotein metabolic process+++GO:0042752///regulation of circadian rhythm+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045070///positive regulation of viral genome replication+++GO:0045471///response to ethanol+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0045820///negative regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045923///positive regulation of fatty acid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048511///rhythmic process+++GO:0050728///negative regulation of inflammatory response+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0070166///enamel mineralization+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903944///negative regulation of hepatocyte apoptotic process+++GO:2000272///negative regulation of signaling receptor activity+++GO:2001171///positive regulation of ATP biosynthetic process" 19014 19014 'Med1' mRNA 1309 1190 1219 16.16 13.88 16.28 16.32 15.48 16.32 15.44 16.04 1490 1354 1422 1239.333333 1422 0.03868399 0.185444138 01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016592///mediator complex+++GO:0032993///protein-DNA complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0050693///LBD domain binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0002088///lens development in camera-type eye+++GO:0002154///thyroid hormone mediated signaling pathway+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003406///retinal pigment epithelium development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006590///thyroid hormone generation+++GO:0006606///protein import into nucleus+++GO:0006702///androgen biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016567///protein ubiquitination+++GO:0030216///keratinocyte differentiation+++GO:0030224///monocyte differentiation+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0031100///animal organ regeneration+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0035050///embryonic heart tube development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035162///embryonic hemopoiesis+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035855///megakaryocyte development+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048821///erythrocyte development+++GO:0048822///enucleate erythrocyte development+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060745///mammary gland branching involved in pregnancy+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation+++GO:0070318///positive regulation of G0 to G1 transition+++GO:0070562///regulation of vitamin D receptor signaling pathway+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2001141///regulation of RNA biosynthetic process" 19015 19015 'Ppard' mRNA 118 95 80 2.06 1.67 1.53 2.63 2.26 2.74 1.753333333 2.543333333 168 141 170 97.66666667 159.6666667 0.002977391 0.700498922 03320///PPAR signaling pathway+++04310///Wnt signaling pathway+++05200///Pathways in cancer+++05221///Acute myeloid leukemia GO:0000785///chromatin+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0008134///transcription factor binding+++GO:0008144///drug binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0016501///prostacyclin receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0070539///linoleic acid binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001890///placenta development+++GO:0006029///proteoglycan metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006776///vitamin A metabolic process+++GO:0006915///apoptotic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0007566///embryo implantation+++GO:0008284///positive regulation of cell proliferation+++GO:0008366///axon ensheathment+++GO:0008544///epidermis development+++GO:0008654///phospholipid biosynthetic process+++GO:0009749///response to glucose+++GO:0009755///hormone-mediated signaling pathway+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0010628///positive regulation of gene expression+++GO:0010887///negative regulation of cholesterol storage+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014823///response to activity+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0015908///fatty acid transport+++GO:0019216///regulation of lipid metabolic process+++GO:0019395///fatty acid oxidation+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030522///intracellular receptor signaling pathway+++GO:0031589///cell-substrate adhesion+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033189///response to vitamin A+++GO:0033993///response to lipid+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042311///vasodilation+++GO:0042640///anagen+++GO:0043066///negative regulation of apoptotic process+++GO:0043415///positive regulation of skeletal muscle tissue regeneration+++GO:0043616///keratinocyte proliferation+++GO:0045598///regulation of fat cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045684///positive regulation of epidermis development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045923///positive regulation of fatty acid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0046697///decidualization+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0050790///regulation of catalytic activity+++GO:0050796///regulation of insulin secretion+++GO:0051546///keratinocyte migration+++GO:0060612///adipose tissue development+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071456///cellular response to hypoxia+++GO:0097190///apoptotic signaling pathway+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:2000288///positive regulation of myoblast proliferation" 19016 19016 'Pparg' mRNA 4 1 2 0.13 0.03 0.07 0.83 1.46 1.07 0.076666667 1.12 34 55 45 2.333333333 44.66666667 1.03E-08 4.252154123 03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04380///Osteoclast differentiation+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05016///Huntington disease+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05216///Thyroid cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0033613///activating transcription factor binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0050544///arachidonic acid binding+++GO:0050692///DBD domain binding+++GO:0050693///LBD domain binding+++GO:0050699///WW domain binding+++GO:0051393///alpha-actinin binding+++GO:0070412///R-SMAD binding+++GO:0070888///E-box binding+++GO:0097677///STAT family protein binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001818///negative regulation of cytokine production+++GO:0001890///placenta development+++GO:0002021///response to dietary excess+++GO:0002024///diet induced thermogenesis+++GO:0002246///wound healing involved in inflammatory response+++GO:0002674///negative regulation of acute inflammatory response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006631///fatty acid metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007507///heart development+++GO:0008217///regulation of blood pressure+++GO:0008285///negative regulation of cell proliferation+++GO:0009409///response to cold+++GO:0009416///response to light stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009755///hormone-mediated signaling pathway+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010742///macrophage derived foam cell differentiation+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0014070///response to organic cyclic compound+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0015909///long-chain fatty acid transport+++GO:0016525///negative regulation of angiogenesis+++GO:0019216///regulation of lipid metabolic process+++GO:0019395///fatty acid oxidation+++GO:0030154///cell differentiation+++GO:0030224///monocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0031000///response to caffeine+++GO:0031100///animal organ regeneration+++GO:0032094///response to food+++GO:0032869///cellular response to insulin stimulus+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033189///response to vitamin A+++GO:0033993///response to lipid+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0035902///response to immobilization stress+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0042594///response to starvation+++GO:0042752///regulation of circadian rhythm+++GO:0042953///lipoprotein transport+++GO:0043065///positive regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043627///response to estrogen+++GO:0045165///cell fate commitment+++GO:0045444///fat cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045923///positive regulation of fatty acid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048469///cell maturation+++GO:0048511///rhythmic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051974///negative regulation of telomerase activity+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060965///negative regulation of gene silencing by miRNA+++GO:0061411///positive regulation of transcription from RNA polymerase II promoter in response to cold+++GO:0071285///cellular response to lithium ion+++GO:0071300///cellular response to retinoic acid+++GO:0071306///cellular response to vitamin E+++GO:0071379///cellular response to prostaglandin stimulus+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071455///cellular response to hyperoxia+++GO:0090258///negative regulation of mitochondrial fission+++GO:0090278///negative regulation of peptide hormone secretion+++GO:0106106///cold-induced thermogenesis+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1900077///negative regulation of cellular response to insulin stimulus+++GO:1901558///response to metformin+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903845///negative regulation of cellular response to transforming growth factor beta stimulus+++GO:1903979///negative regulation of microglial cell activation+++GO:1904179///positive regulation of adipose tissue development+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904893///negative regulation of STAT cascade+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:1905563///negative regulation of vascular endothelial cell proliferation+++GO:1905599///positive regulation of low-density lipoprotein receptor activity+++GO:2000230///negative regulation of pancreatic stellate cell proliferation+++GO:2000272///negative regulation of signaling receptor activity" 19017 19017 'Ppargc1a' mRNA 1273.1 1348.73 1207 10.31 10.71 10.42 7.41 5.64 6.96 10.48 6.67 1048 777 953.04 1276.276667 926.0133333 4.06E-06 -0.475329904 04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04936///Alcoholic liver disease+++05016///Huntington disease GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body+++GO:0022626///cytosolic ribosome+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097440///apical dendrite GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0043014///alpha-tubulin binding+++GO:0043565///sequence-specific DNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000302///response to reactive oxygen species+++GO:0000422///autophagy of mitochondrion+++GO:0001666///response to hypoxia+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002021///response to dietary excess+++GO:0002931///response to ischemia+++GO:0006012///galactose metabolic process+++GO:0006094///gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007005///mitochondrion organization+++GO:0007568///aging+++GO:0008209///androgen metabolic process+++GO:0009409///response to cold+++GO:0009750///response to fructose+++GO:0010628///positive regulation of gene expression+++GO:0010822///positive regulation of mitochondrion organization+++GO:0014070///response to organic cyclic compound+++GO:0014732///skeletal muscle atrophy+++GO:0014823///response to activity+++GO:0014850///response to muscle activity+++GO:0014878///response to electrical stimulus involved in regulation of muscle adaptation+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0019395///fatty acid oxidation+++GO:0021549///cerebellum development+++GO:0022904///respiratory electron transport chain+++GO:0030900///forebrain development+++GO:0031325///positive regulation of cellular metabolic process+++GO:0031667///response to nutrient levels+++GO:0032922///circadian regulation of gene expression+++GO:0034599///cellular response to oxidative stress+++GO:0035865///cellular response to potassium ion+++GO:0042493///response to drug+++GO:0042594///response to starvation+++GO:0042752///regulation of circadian rhythm+++GO:0043201///response to leucine+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045820///negative regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0048511///rhythmic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051552///flavone metabolic process+++GO:0051602///response to electrical stimulus+++GO:0060612///adipose tissue development+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071250///cellular response to nitrite+++GO:0071313///cellular response to caffeine+++GO:0071332///cellular response to fructose stimulus+++GO:0071333///cellular response to glucose stimulus+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071456///cellular response to hypoxia+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071871///response to epinephrine+++GO:0071873///response to norepinephrine+++GO:0090258///negative regulation of mitochondrial fission+++GO:0097009///energy homeostasis+++GO:0097066///response to thyroid hormone+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901215///negative regulation of neuron death+++GO:1901558///response to metformin+++GO:1901857///positive regulation of cellular respiration+++GO:1901860///positive regulation of mitochondrial DNA metabolic process+++GO:1901863///positive regulation of muscle tissue development+++GO:1904635///positive regulation of glomerular visceral epithelial cell apoptotic process+++GO:1904637///cellular response to ionomycin+++GO:1904639///cellular response to resveratrol+++GO:1904640///response to methionine+++GO:1990845///adaptive thermogenesis+++GO:2000184///positive regulation of progesterone biosynthetic process+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000310///regulation of NMDA receptor activity+++GO:2001171///positive regulation of ATP biosynthetic process" 19018 19018 'Scand1' mRNA 419.19 425.59 182.39 38.23 38.5 17.65 19.76 45.61 40.36 31.46 35.24333333 247.84 556.96 488.71 342.39 431.17 0.600324248 0.345567668 GO:0005634///nucleus "GO:0045893///positive regulation of transcription, DNA-templated" 19023 19023 'Ppef2' mRNA 21 17 21 0.36 0.32 0.39 0.2 0.24 0.15 0.356666667 0.196666667 12 15 9 19.66666667 12 0.303255739 -0.726648827 04745///Phototransduction - fly GO:0005634///nucleus+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005506///iron ion binding+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0030544///Hsp70 protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding GO:0006470///protein dephosphorylation+++GO:0007601///visual perception+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0050896///response to stimulus+++GO:0050906///detection of stimulus involved in sensory perception 19024 19024 'Ppfibp2' mRNA 1883.15 1951.02 1920.01 28.96 29.76 31.65 15.07 14.62 13.98 30.12333333 14.55666667 1122.03 1063.07 1020.19 1918.06 1068.43 7.76E-28 -0.857230667 GO:0048786///presynaptic active zone+++GO:0098793///presynapse GO:0042802///identical protein binding GO:0007528///neuromuscular junction development+++GO:0050808///synapse organization 19025 19025 'Ctsa' mRNA 5245.8 5565.55 5265.03 130.89 137.39 140.36 336.75 356.36 345.22 136.2133333 346.11 15328.04 15820.97 15245.33 5358.793333 15464.78 1.23E-171 1.517699376 04142///Lysosome+++04614///Renin-angiotensin system GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004180///carboxypeptidase activity+++GO:0004185///serine-type carboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0031647///regulation of protein stability+++GO:1904715///negative regulation of chaperone-mediated autophagy 19027 19027 'Sypl' mRNA 2163 2278 2140 25.15 26.05 26.4 28.6 27.28 27.92 25.86666667 27.93333333 2832 2639 2678 2193.666667 2716.333333 7.92E-06 0.296263323 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome GO:0017075///syntaxin-1 binding 19035 19035 'Ppib' mRNA 4704.63 4692.33 4623.29 316.56 312.36 330.1 509.75 512.02 511.95 319.6733333 511.24 8683.12 8499.76 8426.18 4673.416667 8536.353333 4.26E-57 0.856869281 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0070063///RNA polymerase binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0030593///neutrophil chemotaxis+++GO:0040018///positive regulation of multicellular organism growth+++GO:0044794///positive regulation by host of viral process+++GO:0044829///positive regulation by host of viral genome replication+++GO:0050821///protein stabilization+++GO:0060348///bone development+++GO:0061077///chaperone-mediated protein folding 19038 19038 'Ppic' mRNA 123 137 147 5.8 6.37 7.35 26.69 26.86 26.62 6.506666667 26.72333333 650 638 627 135.6666667 638.3333333 7.00E-56 2.22059521 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 19039 19039 'Lgals3bp' mRNA 7275 7635 7399 186.26 192.51 200.97 324.54 310.96 312.8 193.2466667 316.1 14575 13636 13599 7436.333333 13936.66667 3.39E-63 0.893275062 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane GO:0005044///scavenger receptor activity+++GO:0005515///protein binding GO:0006897///endocytosis+++GO:0007155///cell adhesion 19041 19041 'Ppl' mRNA 487 466 477 4.11 3.87 4.27 5.81 5.29 5.09 4.083333333 5.396666667 792 705 672 476.6666667 723 2.04E-07 0.587425805 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0005198///structural molecule activity+++GO:0005515///protein binding GO:0009612///response to mechanical stimulus+++GO:0031424///keratinization+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization 19042 19042 'Ppm1a' mRNA 680 719 760 6.86 7.35 8.09 6.08 5.62 6.65 7.433333333 6.116666667 558 543 638 719.6666667 579.6666667 0.008699669 -0.326200845 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030145///manganese ion binding+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0043169///cation binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding "GO:0006470///protein dephosphorylation+++GO:0006499///N-terminal protein myristoylation+++GO:0010991///negative regulation of SMAD protein complex assembly+++GO:0016311///dephosphorylation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046827///positive regulation of protein export from nucleus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1901223///negative regulation of NIK/NF-kappaB signaling" 19043 19043 'Ppm1b' mRNA 708 683 647 13.83 13.19 13.29 11.67 10.17 11.3 13.43666667 11.04666667 689 590 640 679.3333333 639.6666667 0.435222433 -0.098904101 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030145///manganese ion binding+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0006499///N-terminal protein myristoylation+++GO:0016311///dephosphorylation+++GO:0032688///negative regulation of interferon-beta production+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050687///negative regulation of defense response to virus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 19044 19044 'Ppox' mRNA 1070 1138 1047 34.18 35.84 35.54 21.78 21.32 22.97 35.18666667 22.02333333 784 751 802 1085 779 5.20E-08 -0.489257528 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031304///intrinsic component of mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0004729///oxygen-dependent protoporphyrinogen oxidase activity+++GO:0016491///oxidoreductase activity GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0042493///response to drug+++GO:0046501///protoporphyrinogen IX metabolic process 19045 19045 'Ppp1ca' mRNA 3546.67 3689.31 3633.26 156.14 160.28 169.7 253.4 272.69 259.93 162.04 262.0066667 6609.37 6938.55 6557.63 3623.08 6701.85 2.43E-44 0.875333029 03015///mRNA surveillance pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04720///Long-term potentiation+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04921///Oxytocin signaling pathway+++04931///Insulin resistance+++05031///Amphetamine addiction+++05034///Alcoholism+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy "GO:0000164///protein phosphatase type 1 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0042587///glycogen granule+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0098641///cadherin binding involved in cell-cell adhesion GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006417///regulation of translation+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0009987///cellular process+++GO:0010288///response to lead ion+++GO:0016311///dephosphorylation+++GO:0030324///lung development+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0048511///rhythmic process+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0051301///cell division+++GO:0098609///cell-cell adhesion+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 19046 19046 'Ppp1cb' mRNA 3605 3590 3042 48.34 47.36 43.27 28.98 25.7 26.93 46.32333333 27.20333333 2487 2155 2239 3412.333333 2293.666667 4.35E-17 -0.58297346 03015///mRNA surveillance pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04720///Long-term potentiation+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04921///Oxytocin signaling pathway+++04931///Insulin resistance+++05031///Amphetamine addiction+++05034///Alcoholism+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy "GO:0000164///protein phosphatase type 1 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0042587///glycogen granule+++GO:0072357///PTW/PP1 phosphatase complex" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017018///myosin phosphatase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0050115///myosin-light-chain-phosphatase activity GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0030155///regulation of cell adhesion+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0048511///rhythmic process+++GO:0051301///cell division 19047 19047 'Ppp1cc' mRNA 646.98 558.51 479.36 15.16 12.89 11.92 19.2 17.16 19 13.32333333 18.45333333 942.32 822.4 890.86 561.6166667 885.1933333 7.48E-09 0.64799147 03015///mRNA surveillance pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04720///Long-term potentiation+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04921///Oxytocin signaling pathway+++04931///Insulin resistance+++05031///Amphetamine addiction+++05034///Alcoholism+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy "GO:0000164///protein phosphatase type 1 complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0008022///protein C-terminus binding+++GO:0008157///protein phosphatase 1 binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0048511///rhythmic process+++GO:0051301///cell division+++GO:0060252///positive regulation of glial cell proliferation 19049 19049 'Ppp1r1b' mRNA 4774 4848 4558 172.63 170.05 178.41 105.9 106.96 104.61 173.6966667 105.8233333 3344 3313 3154 4726.666667 3270.333333 4.66E-21 -0.542737766 04024///cAMP signaling pathway+++04728///Dopaminergic synapse+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0044326///dendritic spine neck+++GO:0044327///dendritic spine head+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0031748///D1 dopamine receptor binding+++GO:0031749///D2 dopamine receptor binding+++GO:0031750///D3 dopamine receptor binding+++GO:0031751///D4 dopamine receptor binding+++GO:0031752///D5 dopamine receptor binding "GO:0001975///response to amphetamine+++GO:0006351///transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0007613///memory+++GO:0007621///negative regulation of female receptivity+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0035094///response to nicotine+++GO:0035556///intracellular signal transduction+++GO:0042220///response to cocaine+++GO:0043086///negative regulation of catalytic activity+++GO:0043278///response to morphine+++GO:0043987///histone H3-S10 phosphorylation+++GO:0048148///behavioral response to cocaine+++GO:0071314///cellular response to cocaine" 19052 19052 'Ppp2ca' mRNA 475 552 466 14.07 16.11 14.64 20.92 19.21 20.79 14.94 20.30666667 812 728 781 497.6666667 773.6666667 6.82E-09 0.625837838 03015///mRNA surveillance pathway+++04013///MAPK signaling pathway - fly+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04136///Autophagy - other+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++04730///Long-term depression+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection "GO:0000159///protein phosphatase type 2A complex+++GO:0000775///chromosome, centromeric region+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0045121///membrane raft+++GO:0045202///synapse" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0042802///identical protein binding+++GO:0043422///protein kinase B binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0048156///tau protein binding+++GO:0050811///GABA receptor binding+++GO:0051721///protein phosphatase 2A binding+++GO:1990405///protein antigen binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0007498///mesoderm development+++GO:0010288///response to lead ion+++GO:0010469///regulation of signaling receptor activity+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0031952///regulation of protein autophosphorylation+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0042176///regulation of protein catabolic process+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051321///meiotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0071333///cellular response to glucose stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901020///negative regulation of calcium ion transmembrane transporter activity+++GO:1904528///positive regulation of microtubule binding 19053 19053 'Ppp2cb' mRNA 328.35 281.97 296.81 10.93 9.52 10.82 11.38 11.45 10.72 10.42333333 11.18333333 374.83 376.37 351.73 302.3766667 367.6433333 0.080509098 0.270680081 03015///mRNA surveillance pathway+++04013///MAPK signaling pathway - fly+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04136///Autophagy - other+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++04730///Long-term depression+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection "GO:0000159///protein phosphatase type 2A complex+++GO:0000775///chromosome, centromeric region+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0008637///apoptotic mitochondrial changes+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042542///response to hydrogen peroxide+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046677///response to antibiotic+++GO:1904528///positive regulation of microtubule binding 19054 19054 'Ppp2r3d' mRNA 1236.64 1133.13 922.87 26.24 24.21 20.24 12.48 13.02 12.98 23.56333333 12.82666667 620.42 642.3 625.98 1097.546667 629.5666667 1.09E-14 -0.809238715 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0003682///chromatin binding+++GO:0004723///calcium-dependent protein serine/threonine phosphatase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding" GO:0001754///eye photoreceptor cell differentiation+++GO:0006470///protein dephosphorylation+++GO:0007525///somatic muscle development+++GO:0008285///negative regulation of cell proliferation+++GO:0045732///positive regulation of protein catabolic process+++GO:0050790///regulation of catalytic activity+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090249///regulation of cell motility involved in somitogenic axis elongation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 19055 19055 'Ppp3ca' mRNA 1515 1504 1102 17.46 16.96 13.44 12.17 11.15 11.38 15.95333333 11.56666667 1222 1107 1124 1373.666667 1151 0.0137709 -0.261404181 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0036057///slit diaphragm+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004723///calcium-dependent protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0016018///cyclosporin A binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0051117///ATPase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001975///response to amphetamine+++GO:0006470///protein dephosphorylation+++GO:0006606///protein import into nucleus+++GO:0006816///calcium ion transport+++GO:0007420///brain development+++GO:0007568///aging+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014883///transition between fast and slow fiber+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0016311///dephosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0030335///positive regulation of cell migration+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0033555///multicellular organismal response to stress+++GO:0035562///negative regulation of chromatin binding+++GO:0045785///positive regulation of cell adhesion+++GO:0045807///positive regulation of endocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0048741///skeletal muscle fiber development+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051592///response to calcium ion+++GO:0060079///excitatory postsynaptic potential+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0071333///cellular response to glucose stimulus+++GO:0097720///calcineurin-mediated signaling+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:1903244///positive regulation of cardiac muscle hypertrophy in response to stress+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1905205///positive regulation of connective tissue replacement 19056 19056 'Ppp3cb' mRNA 501 519 436 9.91 9.95 9.06 9.03 8.24 9.19 9.64 8.82 551 465 514 485.3333333 510 0.704024236 0.06126229 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004723///calcium-dependent protein serine/threonine phosphatase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030346///protein phosphatase 2B binding+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0001946///lymphangiogenesis+++GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006950///response to stress+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0017156///calcium ion regulated exocytosis+++GO:0030217///T cell differentiation+++GO:0031987///locomotion involved in locomotory behavior+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0034097///response to cytokine+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0043029///T cell homeostasis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050796///regulation of insulin secretion+++GO:0097720///calcineurin-mediated signaling+++GO:1900242///regulation of synaptic vesicle endocytosis 19057 19057 'Ppp3cc' mRNA 220 229 142 5.07 5.02 3 2.74 1.89 2.27 4.363333333 2.3 133 92 117 197 114 6.94E-04 -0.794510697 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005955///calcineurin complex+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0016787///hydrolase activity+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0007420///brain development+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0097720///calcineurin-mediated signaling+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis 19058 19058 'Ppp3r1' mRNA 2076 2156 2083 40.48 41.38 43.09 60.25 59.22 57.43 41.65 58.96666667 3555 3412 3281 2105 3416 4.32E-26 0.686081766 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04720///Long-term potentiation+++04724///Glutamatergic synapse+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004721///phosphoprotein phosphatase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0016018///cyclosporin A binding+++GO:0019899///enzyme binding+++GO:0019902///phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0006470///protein dephosphorylation+++GO:0006606///protein import into nucleus+++GO:0007507///heart development+++GO:0014044///Schwann cell development+++GO:0022011///myelination in peripheral nervous system+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0034504///protein localization to nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0060487///lung epithelial cell differentiation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0099170///postsynaptic modulation of chemical synaptic transmission 19060 19060 'Ppp5c' mRNA 2050 2024 2039 57.84 56.46 60.85 50.8 48.72 47.93 58.38333333 49.15 2053 1933 1889 2037.666667 1958.333333 0.424634732 -0.070430209 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071944///cell periphery+++GO:0101031///chaperone complex+++GO:1990635///proximal dendrite GO:0001965///G-protein alpha-subunit binding+++GO:0003723///RNA binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0010288///response to lead ion+++GO:0016576///histone dephosphorylation+++GO:0043278///response to morphine+++GO:0060548///negative regulation of cell death+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071276///cellular response to cadmium ion+++GO:1901215///negative regulation of neuron death+++GO:1904550///response to arachidonic acid+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway 19062 19062 'Inpp5k' mRNA 1648 1670 1559 34.04 34.15 34.29 28.69 25.39 26.33 34.16 26.80333333 1595 1381 1413 1625.666667 1463 0.050328088 -0.164396331 00562///Inositol phosphate metabolism GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0005000///vasopressin receptor activity+++GO:0005515///protein binding+++GO:0016312///inositol bisphosphate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0034594///phosphatidylinositol trisphosphate phosphatase activity+++GO:0034595///phosphatidylinositol phosphate 5-phosphatase activity+++GO:0046030///inositol trisphosphate phosphatase activity+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity" "GO:0001701///in utero embryonic development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0006469///negative regulation of protein kinase activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010829///negative regulation of glucose transmembrane transport+++GO:0016311///dephosphorylation+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035305///negative regulation of dephosphorylation+++GO:0035810///positive regulation of urine volume+++GO:0042593///glucose homeostasis+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043922///negative regulation by host of viral transcription+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0051926///negative regulation of calcium ion transport+++GO:0071320///cellular response to cAMP+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0097178///ruffle assembly+++GO:2000466///negative regulation of glycogen (starch) synthase activity+++GO:2001153///positive regulation of renal water transport" 19063 19063 'Ppt1' mRNA 5382.26 5697.25 5553 120.31 125.38 131.68 143.39 138.63 141.05 125.79 141.0233333 7378.37 6965.78 7026.58 5544.17 7123.576667 2.40E-09 0.348547449 00062///Fatty acid elongation+++01212///Fatty acid metabolism+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0035727///lysophosphatidic acid binding+++GO:0098599///palmitoyl hydrolase activity+++GO:0120146///sulfatide binding GO:0002084///protein depalmitoylation+++GO:0006898///receptor-mediated endocytosis+++GO:0006907///pinocytosis+++GO:0007040///lysosome organization+++GO:0007042///lysosomal lumen acidification+++GO:0007269///neurotransmitter secretion+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007601///visual perception+++GO:0007625///grooming behavior+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0015031///protein transport+++GO:0016042///lipid catabolic process+++GO:0030308///negative regulation of cell growth+++GO:0031579///membrane raft organization+++GO:0032429///regulation of phospholipase A2 activity+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044257///cellular protein catabolic process+++GO:0044265///cellular macromolecule catabolic process+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048549///positive regulation of pinocytosis 19065 19065 'Npy4r' mRNA 0 0 1 0 0 0.03 0.1 0 0.05 0.01 0.05 4 0 2 0.333333333 2 0.425566073 2.451652925 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001601///peptide YY receptor activity+++GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 19069 19069 'Nup88' mRNA 1485 1496 1494 33.73 33.46 35.99 34.94 32.23 31.66 34.39333333 32.94333333 1769 1593 1552 1491.666667 1638 0.179929007 0.121478751 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm GO:0017056///structural constituent of nuclear pore GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000278///mitotic cell cycle+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051028///mRNA transport 19070 19070 'Mob4' mRNA 1881.16 1898.51 1712.93 36.79 36.52 35.54 33.92 32.31 34.71 36.28333333 33.64666667 1997.34 1856.08 1976.69 1830.866667 1943.37 0.359103966 0.075472544 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0048471///perinuclear region of cytoplasm GO:0019900///kinase binding+++GO:0046872///metal ion binding 19072 19072 'Prep' mRNA 825.99 772 806 10.7 9.59 10.83 13.86 12.85 13.7 10.37333333 13.47 1255 1144 1160 801.33 1186.333333 1.62E-09 0.55311332 04614///Renin-angiotensin system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0070012///oligopeptidase activity GO:0006508///proteolysis+++GO:0019538///protein metabolic process 19073 19073 'Srgn' mRNA 4007 4141 4054 222.25 224.11 236.58 933.77 949.98 963.49 227.6466667 949.08 19357 19167 19307 4067.333333 19277 0 2.232435148 "GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0042588///zymogen granule+++GO:0042629///mast cell granule+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component" GO:0005515///protein binding+++GO:0005518///collagen binding GO:0001818///negative regulation of cytokine production+++GO:0006915///apoptotic process+++GO:0016485///protein processing+++GO:0030502///negative regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0033363///secretory granule organization+++GO:0033364///mast cell secretory granule organization+++GO:0033371///T cell secretory granule organization+++GO:0033373///maintenance of protease location in mast cell secretory granule+++GO:0033382///maintenance of granzyme B location in T cell secretory granule+++GO:0050804///modulation of chemical synaptic transmission+++GO:0099175///regulation of postsynapse organization 19074 19074 'Prg2' mRNA 1 0 1 0.08 0 0.09 0.07 0.07 0.07 0.056666667 0.07 1 1 1 0.666666667 1 0.863357859 0.55598467 05310///Asthma GO:0062023///collagen-containing extracellular matrix GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030246///carbohydrate binding GO:0002215///defense response to nematode+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042742///defense response to bacterium 19075 19075 'Prim1' mRNA 186 197 183 7.15 7.46 7.46 12.21 12 12.03 7.356666667 12.08 365 350 348 188.6666667 354.3333333 2.40E-09 0.89782182 03030///DNA replication GO:0005658///alpha DNA polymerase:primase complex+++GO:1990077///primosome complex GO:0000287///magnesium ion binding+++GO:0003896///DNA primase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0032553///ribonucleotide binding+++GO:0046872///metal ion binding "GO:0006260///DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer" 19076 19076 'Prim2' mRNA 112 125 95 3.22 3.52 2.93 4.64 4.59 5.54 3.223333333 4.923333333 185 175 214 110.6666667 191.3333333 2.19E-04 0.782077311 03030///DNA replication GO:0005658///alpha DNA polymerase:primase complex+++GO:1990077///primosome complex "GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0071667///DNA/RNA hybrid binding" "GO:0006260///DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:1903934///positive regulation of DNA primase activity" 19079 19079 'Prkab1' mRNA 1123 1056 1197 31.04 28.75 35.07 23.47 25.12 25.02 31.62 24.53666667 976 1020 1007 1125.333333 1001 0.095401892 -0.183386949 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0032991///protein-containing complex GO:0004672///protein kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0035878///nail development+++GO:0050790///regulation of catalytic activity+++GO:0080090///regulation of primary metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis 19082 19082 'Prkag1' mRNA 1982 2082 1978 70.31 72.83 74.5 58.85 57.93 64.79 72.54666667 60.52333333 1903 1828 2029 2014 1920 0.361502993 -0.08076306 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0032559///adenyl ribonucleotide binding+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0010628///positive regulation of gene expression+++GO:0042149///cellular response to glucose starvation+++GO:0050790///regulation of catalytic activity+++GO:0051170///import into nucleus+++GO:0071900///regulation of protein serine/threonine kinase activity 19084 19084 'Prkar1a' mRNA 8802 9366 9539 143.6 150.34 165.13 202.17 206.39 196.18 153.0233333 201.58 14272 14210 13413 9235.666667 13965 6.45E-20 0.582643129 04910///Insulin signaling pathway GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0005930///axoneme+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0097224///sperm connecting piece+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0016301///kinase activity+++GO:0019904///protein domain specific binding+++GO:0030552///cAMP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034236///protein kinase A catalytic subunit binding GO:0001707///mesoderm formation+++GO:0001932///regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007143///female meiotic nuclear division+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010738///regulation of protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045214///sarcomere organization+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0045859///regulation of protein kinase activity+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0060038///cardiac muscle cell proliferation+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 19085 19085 'Prkar1b' mRNA 447.5 499.24 429 9.46 10.33 9.55 13.19 11.73 10.96 9.78 11.96 720 626 577.32 458.58 641.1066667 1.09E-04 0.472477819 04910///Insulin signaling pathway GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0016301///kinase activity+++GO:0030552///cAMP binding+++GO:0034236///protein kinase A catalytic subunit binding GO:0001932///regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007611///learning or memory+++GO:0009887///animal organ morphogenesis+++GO:0010738///regulation of protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045859///regulation of protein kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0098693///regulation of synaptic vesicle cycle+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 19087 19087 'Prkar2a' mRNA 800 823 674 8.6 8.7 7.68 6.51 5.6 5.86 8.326666667 5.99 697 586 608 765.6666667 630.3333333 0.009688383 -0.290381008 04910///Insulin signaling pathway GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005930///axoneme+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0032991///protein-containing complex+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0016301///kinase activity+++GO:0019904///protein domain specific binding+++GO:0030552///cAMP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0036094///small molecule binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001932///regulation of protein phosphorylation+++GO:0010738///regulation of protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045859///regulation of protein kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 19088 19088 'Prkar2b' mRNA 393 413 185 6.41 6.65 3.53 3.01 2.71 3.58 5.53 3.1 197 170 222 330.3333333 196.3333333 0.00176868 -0.747237326 04910///Insulin signaling pathway GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0097546///ciliary base+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030552///cAMP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034236///protein kinase A catalytic subunit binding GO:0001932///regulation of protein phosphorylation+++GO:0006631///fatty acid metabolic process+++GO:0007612///learning+++GO:0010738///regulation of protein kinase A signaling+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045859///regulation of protein kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0097332///response to antipsychotic drug+++GO:0097338///response to clozapine+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity 19089 19089 'Prkcsh' mRNA 2745 2897 2698 76.16 78.78 79.21 88.69 82.8 88.63 78.05 86.70666667 3681 3372 3567 2780 3540 6.56E-08 0.336692733 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0017177///glucosidase II complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003723///RNA binding+++GO:0005080///protein kinase C binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0006491///N-glycan processing+++GO:0006807///nitrogen compound metabolic process+++GO:0010977///negative regulation of neuron projection development 19090 19090 'Prkdc' mRNA 575 627 527 2.38 2.61 2.3 1.85 1.79 1.81 2.43 1.816666667 508 487 487 576.3333333 494 0.054143831 -0.232050119 03450///Non-homologous end-joining+++04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005958///DNA-dependent protein kinase-DNA ligase 4 complex+++GO:0032040///small-subunit processome+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0070419///nonhomologous end joining complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004677///DNA-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0034511///U3 snoRNA binding GO:0000460///maturation of 5.8S rRNA+++GO:0000723///telomere maintenance+++GO:0001756///somitogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002218///activation of innate immune response+++GO:0002326///B cell lineage commitment+++GO:0002328///pro-B cell differentiation+++GO:0002360///T cell lineage commitment+++GO:0002376///immune system process+++GO:0002638///negative regulation of immunoglobulin production+++GO:0002684///positive regulation of immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010212///response to ionizing radiation+++GO:0010332///response to gamma radiation+++GO:0014823///response to activity+++GO:0016233///telomere capping+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030098///lymphocyte differentiation+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0031648///protein destabilization+++GO:0032869///cellular response to insulin stimulus+++GO:0033077///T cell differentiation in thymus+++GO:0033151///V(D)J recombination+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0033153///T cell receptor V(D)J recombination+++GO:0034462///small-subunit processome assembly+++GO:0035234///ectopic germ cell programmed cell death+++GO:0042254///ribosome biogenesis+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048511///rhythmic process+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048639///positive regulation of developmental growth+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0050678///regulation of epithelial cell proliferation+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:1905221///positive regulation of platelet formation+++GO:2000773///negative regulation of cellular senescence+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:2001229///negative regulation of response to gamma radiation 19091 19091 'Prkg1' mRNA 377 365 305 2.88 2.73 2.47 0.56 0.44 0.52 2.693333333 0.506666667 84 65 74 349 74.33333333 7.05E-34 -2.240841173 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04730///Long-term depression+++04740///Olfactory transduction+++04923///Regulation of lipolysis in adipocytes+++04970///Salivary secretion GO:0001669///acrosomal vesicle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004692///cGMP-dependent protein kinase activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030553///cGMP binding+++GO:0042802///identical protein binding+++GO:0048273///mitogen-activated protein kinase p38 binding GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008152///metabolic process+++GO:0010920///negative regulation of inositol phosphate biosynthetic process+++GO:0014050///negative regulation of glutamate secretion+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016358///dendrite development+++GO:0019934///cGMP-mediated signaling+++GO:0030900///forebrain development+++GO:0042753///positive regulation of circadian rhythm+++GO:0043087///regulation of GTPase activity+++GO:0045822///negative regulation of heart contraction+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0060087///relaxation of vascular smooth muscle+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0090331///negative regulation of platelet aggregation+++GO:1902608///positive regulation of large conductance calcium-activated potassium channel activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:2000224///regulation of testosterone biosynthetic process 19092 19092 'Prkg2' mRNA 68 55 57 1.07 1.13 1.03 0.64 0.4 0.48 1.076666667 0.506666667 40 31 33 60 34.66666667 0.033067672 -0.8046727 04022///cGMP-PKG signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04730///Long-term depression+++04740///Olfactory transduction+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04970///Salivary secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031965///nuclear membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004692///cGMP-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030553///cGMP binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0007623///circadian rhythm+++GO:0016310///phosphorylation+++GO:0032922///circadian regulation of gene expression+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0045794///negative regulation of cell volume+++GO:0071476///cellular hypotonic response+++GO:0072659///protein localization to plasma membrane+++GO:2001226///negative regulation of chloride transport 19094 19094 'Mapk11' mRNA 31 29 31 0.71 0.65 0.75 2.32 1.91 2.44 0.703333333 2.223333333 117 94 119 30.33333333 110 2.01E-09 1.844645651 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0001649///osteoblast differentiation+++GO:0006468///protein phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0032735///positive regulation of interleukin-12 production+++GO:0035556///intracellular signal transduction+++GO:0051403///stress-activated MAPK cascade+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060348///bone development+++GO:0071347///cellular response to interleukin-1+++GO:0098586///cellular response to virus 19099 19099 'Mapk8ip1' mRNA 2293 2218 1333 40.53 38.77 24.7 12.62 11.9 11.19 34.66666667 11.90333333 797 746 694 1948 745.6666667 3.41E-25 -1.38658406 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0044302///dentate gyrus mossy fiber+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0007258///JUN phosphorylation+++GO:0016192///vesicle-mediated transport+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0046328///regulation of JNK cascade+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:2000564///regulation of CD8-positive, alpha-beta T cell proliferation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 19106 19106 'Eif2ak2' mRNA 649.48 626.43 627.44 6.77 6.43 7.02 10.16 9.29 10.08 6.74 9.843333333 1110.55 1035.46 1103.64 634.45 1083.216667 2.55E-16 0.759575939 04141///Protein processing in endoplasmic reticulum+++04217///Necroptosis+++05010///Alzheimer disease+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0000186///activation of MAPKK activity+++GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0006412///translation+++GO:0006468///protein phosphorylation+++GO:0009615///response to virus+++GO:0009636///response to toxic substance+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032496///response to lipopolysaccharide+++GO:0032722///positive regulation of chemokine production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0033197///response to vitamin E+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0034198///cellular response to amino acid starvation+++GO:0035455///response to interferon-alpha+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0046777///protein autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:1900225///regulation of NLRP3 inflammasome complex assembly+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901532///regulation of hematopoietic progenitor cell differentiation+++GO:1902033///regulation of hematopoietic stem cell proliferation+++GO:1902036///regulation of hematopoietic stem cell differentiation 19108 19108 'Prkx' mRNA 1069 1032 1019 13.5 12.81 13.62 15.19 13.91 13.9 13.31 14.33333333 1387 1238 1233 1040 1286 8.92E-04 0.293438912 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005952///cAMP-dependent protein kinase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004691///cAMP-dependent protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001525///angiogenesis+++GO:0001935///endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0031589///cell-substrate adhesion+++GO:0043542///endothelial cell migration+++GO:0046777///protein autophosphorylation+++GO:0060562///epithelial tube morphogenesis+++GO:0060993///kidney morphogenesis+++GO:2000696///regulation of epithelial cell differentiation involved in kidney development 19109 19109 'Prl' mRNA 2 2 5 0.15 0.15 0.39 0.58 0.13 0.2 0.23 0.303333333 9 2 3 3 4.666666667 0.734053465 0.593257626 04060///Cytokine-cytokine receptor interaction+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule GO:0005148///prolactin receptor binding+++GO:0005179///hormone activity GO:0001937///negative regulation of endothelial cell proliferation+++GO:0007165///signal transduction+++GO:0007565///female pregnancy+++GO:0007567///parturition+++GO:0007584///response to nutrient+++GO:0007595///lactation+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0014070///response to organic cyclic compound+++GO:0030278///regulation of ossification+++GO:0030879///mammary gland development+++GO:0031667///response to nutrient levels+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032870///cellular response to hormone stimulus+++GO:0033555///multicellular organismal response to stress+++GO:0042493///response to drug+++GO:0042698///ovulation cycle+++GO:0042711///maternal behavior+++GO:0045471///response to ethanol+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903489///positive regulation of lactation 19116 19116 'Prlr' mRNA 4.04 2.24 1.99 0.12 0.01 0.01 0.2 0.05 0.16 0.046666667 0.136666667 13 9 8 2.756666667 10 0.065962568 2.094333598 04060///Cytokine-cytokine receptor interaction+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0004923///leukemia inhibitory factor receptor activity+++GO:0004924///oncostatin-M receptor activity+++GO:0004925///prolactin receptor activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005515///protein binding+++GO:0017046///peptide hormone binding+++GO:0019901///protein kinase binding+++GO:0019955///cytokine binding+++GO:0046872///metal ion binding GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007259///JAK-STAT cascade+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030155///regulation of cell adhesion+++GO:0030856///regulation of epithelial cell differentiation+++GO:0038161///prolactin signaling pathway+++GO:0038165///oncostatin-M-mediated signaling pathway+++GO:0042976///activation of Janus kinase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0048861///leukemia inhibitory factor signaling pathway+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060736///prostate gland growth+++GO:0060749///mammary gland alveolus development+++GO:0061180///mammary gland epithelium development+++GO:0120162///positive regulation of cold-induced thermogenesis 19120 19120 'Prm3' mRNA 0 0 1 0 0 0.26 0 0 0 0.086666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0003677///DNA binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030261///chromosome condensation+++GO:0030317///flagellated sperm motility 19122 19122 'Prnp' mRNA 13175.05 13376.13 13080.61 276.18 282.97 297.38 189.12 188.55 190.78 285.51 189.4833333 9940.97 9583.39 9687.15 13210.59667 9737.17 7.11E-19 -0.452714469 04216///Ferroptosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016234///inclusion body+++GO:0030425///dendrite+++GO:0031225///anchored component of membrane+++GO:0031965///nuclear membrane+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft GO:0001540///amyloid-beta binding+++GO:0002020///protease binding+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0005539///glycosaminoglycan binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0043008///ATP-dependent protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:1903135///cupric ion binding+++GO:1903136///cuprous ion binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006878///cellular copper ion homeostasis+++GO:0006979///response to oxidative stress+++GO:0007611///learning or memory+++GO:0010942///positive regulation of cell death+++GO:0010951///negative regulation of endopeptidase activity+++GO:0031648///protein destabilization+++GO:0032147///activation of protein kinase activity+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032880///regulation of protein localization+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035690///cellular response to drug+++GO:0042982///amyloid precursor protein metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0046686///response to cadmium ion+++GO:0046688///response to copper ion+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051260///protein homooligomerization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071280///cellular response to copper ion+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0090647///modulation of age-related behavioral decline+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900449///regulation of glutamate receptor signaling pathway+++GO:1901216///positive regulation of neuron death+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902938///regulation of intracellular calcium activated chloride channel activity+++GO:1902951///negative regulation of dendritic spine maintenance+++GO:1902992///negative regulation of amyloid precursor protein catabolic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904645///response to amyloid-beta+++GO:1904646///cellular response to amyloid-beta+++GO:1905664///regulation of calcium ion import across plasma membrane+++GO:1990535///neuron projection maintenance 19124 19124 'Procr' mRNA 82.42 80 72 3.06 2.96 2.89 10.56 9.25 9.95 2.97 9.92 315 270.03 290 78.14 291.6766667 1.07E-23 1.891417191 04610///Complement and coagulation cascades GO:0005615///extracellular space+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0008022///protein C-terminus binding+++GO:0038023///signaling receptor activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0050819///negative regulation of coagulation 19125 19125 'Prodh' mRNA 843 887 901 20.85 21.59 23.55 12.37 13.51 13.19 21.99666667 13.02333333 577 613 597 877 595.6666667 6.13E-08 -0.570778903 00330///Arginine and proline metabolism GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0004657///proline dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016597///amino acid binding+++GO:0071949///FAD binding GO:0006560///proline metabolic process+++GO:0006562///proline catabolic process+++GO:0010133///proline catabolic process to glutamate+++GO:0010942///positive regulation of cell death 19126 19126 'Prom1' mRNA 563 566 570 8.28 8.12 8.76 5.85 5.41 6.37 8.386666667 5.876666667 461 428 492 566.3333333 460.3333333 0.012253816 -0.311867821 05202///Transcriptional misregulation in cancer GO:0001750///photoreceptor outer segment+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane+++GO:0032420///stereocilium+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0071914///prominosome GO:0015485///cholesterol binding+++GO:0042805///actinin binding+++GO:0045296///cadherin binding GO:0010842///retina layer formation+++GO:0045494///photoreceptor cell maintenance+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060219///camera-type eye photoreceptor cell differentiation+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation 19128 19128 'Pros1' mRNA 1076 1250 1180 17.79 20.34 20.76 51.86 54.81 51.13 19.63 52.6 3609 3726 3446 1168.666667 3593.666667 4.42E-95 1.608595192 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005509///calcium ion binding+++GO:0044877///protein-containing complex binding GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030195///negative regulation of blood coagulation+++GO:0042730///fibrinolysis+++GO:0050766///positive regulation of phagocytosis+++GO:0050819///negative regulation of coagulation 19130 19130 'Prox1' mRNA 410 388 367 2.7 2.53 2.56 0.79 0.83 0.6 2.596666667 0.74 139 141 102 388.3333333 127.3333333 1.12E-21 -1.619832428 04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0050692///DBD domain binding+++GO:0050693///LBD domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001709///cell fate determination+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0002194///hepatocyte cell migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010595///positive regulation of endothelial cell migration+++GO:0021542///dentate gyrus development+++GO:0021707///cerebellar granule cell differentiation+++GO:0030240///skeletal muscle thin filament assembly+++GO:0042752///regulation of circadian rhythm+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045071///negative regulation of viral genome replication+++GO:0045446///endothelial cell differentiation+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046619///optic placode formation involved in camera-type eye formation+++GO:0048511///rhythmic process+++GO:0048839///inner ear development+++GO:0048845///venous blood vessel morphogenesis+++GO:0055005///ventricular cardiac myofibril assembly+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060214///endocardium formation+++GO:0060298///positive regulation of sarcomere organization+++GO:0060412///ventricular septum morphogenesis+++GO:0060414///aorta smooth muscle tissue morphogenesis+++GO:0060421///positive regulation of heart growth+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0061114///branching involved in pancreas morphogenesis+++GO:0070309///lens fiber cell morphogenesis+++GO:0070365///hepatocyte differentiation+++GO:0070858///negative regulation of bile acid biosynthetic process+++GO:0072574///hepatocyte proliferation+++GO:0090425///acinar cell differentiation+++GO:0097150///neuronal stem cell population maintenance+++GO:1901978///positive regulation of cell cycle checkpoint+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000979///positive regulation of forebrain neuron differentiation" 19132 19132 'Prph' mRNA 15 16 6 0.48 0.51 0.22 1 1.52 1.51 0.403333333 1.343333333 36 55 52 12.33333333 47.66666667 1.27E-04 1.954777452 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005883///neurofilament+++GO:0030424///axon+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0044299///C-fiber+++GO:0045098///type III intermediate filament GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0045104///intermediate filament cytoskeleton organization 19133 19133 'Prph2' mRNA 179 202 155 3.75 4.17 3.45 0.58 0.63 0.45 3.79 0.553333333 32 34 24 178.6666667 30 9.37E-22 -2.581861307 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0042803///protein homodimerization activity GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0035845///photoreceptor cell outer segment organization+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0051260///protein homooligomerization+++GO:0051291///protein heterooligomerization+++GO:0060041///retina development in camera-type eye 19134 19134 'Prpf4b' mRNA 1848.03 1679 1644 15.24 13.99 15.27 12.09 11.78 11.52 14.83333333 11.79666667 1687 1578 1611 1723.676667 1625.333333 0.274838259 -0.096449722 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0008380///RNA splicing+++GO:0016310///phosphorylation+++GO:0045292///mRNA cis splicing, via spliceosome" 19139 19139 'Prps1' mRNA 1128.98 1262.82 1208.15 32.59 35.92 37 31.71 33.55 28.71 35.17 31.32333333 1262.92 1304.5 1106.52 1199.983333 1224.646667 0.892335216 0.017022774 00030///Pentose phosphate pathway+++00230///Purine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019003///GDP binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046872///metal ion binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006144///purine nucleobase metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006167///AMP biosynthetic process+++GO:0007399///nervous system development+++GO:0009116///nucleoside metabolic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0019693///ribose phosphate metabolic process+++GO:0034418///urate biosynthetic process+++GO:0044249///cellular biosynthetic process+++GO:0046101///hypoxanthine biosynthetic process 19141 19141 'Lgmn' mRNA 7583 8187 7738 225.77 240.18 244.41 671.8 702.02 666.88 236.7866667 680.2333333 25938 26459 24920 7836 25772.33333 4.55E-214 1.705897643 04142///Lysosome+++04612///Antigen processing and presentation GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0003014///renal system process+++GO:0006508///proteolysis+++GO:0006624///vacuolar protein processing+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008306///associative learning+++GO:0010447///response to acidic pH+++GO:0010629///negative regulation of gene expression+++GO:0032801///receptor catabolic process+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0040015///negative regulation of multicellular organism growth+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071277///cellular response to calcium ion+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0097061///dendritic spine organization+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0097264///self proteolysis+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901185///negative regulation of ERBB signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:2001028///positive regulation of endothelial cell chemotaxis 19142 19142 'Prss12' mRNA 335 371 287 7.13 7.78 6.48 5.65 5.73 6.41 7.13 5.93 305 302 335 331 314 0.663821167 -0.083666923 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0043083///synaptic cleft+++GO:0043195///terminal bouton+++GO:0045202///synapse GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0031638///zymogen activation 19143 19143 'St14' mRNA 2467 2845 2741 40.64 46.42 47.84 41.86 40.97 40 44.96666667 40.94333333 2905 2808 2722 2684.333333 2811.666667 0.587715008 0.053599592 05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0019897///extrinsic component of plasma membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001843///neural tube closure+++GO:0006508///proteolysis+++GO:0016477///cell migration+++GO:0030216///keratinocyte differentiation+++GO:0060672///epithelial cell morphogenesis involved in placental branching 19152 19152 'Prtn3' mRNA 29 28 16 1.92 1.83 1.12 6.82 6.4 6.76 1.623333333 6.66 118 108 113 24.33333333 113 8.09E-12 2.210143918 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0035578///azurophil granule lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006909///phagocytosis+++GO:0030574///collagen catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045217///cell-cell junction maintenance+++GO:0050765///negative regulation of phagocytosis+++GO:0072672///neutrophil extravasation+++GO:0097029///mature conventional dendritic cell differentiation 19153 19153 'Prx' mRNA 4629 4870 4314 51.6 53.4 50.6 38.44 36.83 36.84 51.86666667 37.37 3984 3739 3709 4604.333333 3810.666667 7.55E-07 -0.283630225 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0043209///myelin sheath GO:0005515///protein binding GO:0019226///transmission of nerve impulse+++GO:0019233///sensory perception of pain+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0032290///peripheral nervous system myelin formation+++GO:0043484///regulation of RNA splicing 19155 19155 'Npepps' mRNA 1809 1971 1666 24.99 25.82 25.39 24.45 22.2 24.69 25.4 23.78 1986 1804 2027 1815.333333 1939 0.341365344 0.085144223 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0043171///peptide catabolic process+++GO:0071456///cellular response to hypoxia 19156 19156 'Psap' mRNA 11264 11187 8860 237.67 232.52 198.38 498.05 399.32 506.4 222.8566667 467.9233333 27003 21157 26669 10437 24943 2.54E-54 1.2482188 00600///Sphingolipid metabolism+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0016235///aggresome+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0001664///G protein-coupled receptor binding+++GO:0002020///protease binding+++GO:0004565///beta-galactosidase activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0030882///lipid antigen binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0097110///scaffold protein binding+++GO:1905573///ganglioside GM1 binding+++GO:1905574///ganglioside GM2 binding+++GO:1905575///ganglioside GM3 binding+++GO:1905576///ganglioside GT1b binding+++GO:1905577///ganglioside GP1c binding GO:0001865///NK T cell differentiation+++GO:0003335///corneocyte development+++GO:0006629///lipid metabolic process+++GO:0006643///membrane lipid metabolic process+++GO:0006664///glycolipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006678///glucosylceramide metabolic process+++GO:0006683///galactosylceramide catabolic process+++GO:0006886///intracellular protein transport+++GO:0007041///lysosomal transport+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0009306///protein secretion+++GO:0010467///gene expression+++GO:0019216///regulation of lipid metabolic process+++GO:0019882///antigen processing and presentation+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0042552///myelination+++GO:0043408///regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0048589///developmental growth+++GO:0050877///nervous system process+++GO:0050885///neuromuscular process controlling balance+++GO:0051345///positive regulation of hydrolase activity+++GO:0060073///micturition+++GO:0060736///prostate gland growth+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0070841///inclusion body assembly+++GO:0071310///cellular response to organic substance+++GO:0072001///renal system development+++GO:0090102///cochlea development+++GO:0090659///walking behavior+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1903575///cornified envelope assembly+++GO:1903771///positive regulation of beta-galactosidase activity+++GO:1905146///lysosomal protein catabolic process+++GO:1905572///ganglioside GM1 transport to membrane 19157 19157 'Cyth1' mRNA 1170 1082 961 21.1 19.09 18.5 18.56 20.36 19.67 19.56333333 19.53 1196 1274 1219 1071 1229.666667 0.048559358 0.190710351 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031594///neuromuscular junction+++GO:0098888///extrinsic component of presynaptic membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding GO:0030155///regulation of cell adhesion+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0090162///establishment of epithelial cell polarity+++GO:2000300///regulation of synaptic vesicle exocytosis 191578 191578 'Helq' mRNA 244 269 239 3.79 4.08 4.02 2.97 2.8 2.56 3.963333333 2.776666667 219 200 190 250.6666667 203 0.077592853 -0.315696639 GO:0005634///nucleus+++GO:0017117///single-stranded DNA-dependent ATP-dependent DNA helicase complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:1990518///single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006364///rRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032508///DNA duplex unwinding 19158 19158 'Cyth2' mRNA 1236 1380 1002 35.95 40.64 31.46 24.51 34.31 31.19 36.01666667 30.00333333 958 1283 1152 1206 1131 0.528966503 -0.095683454 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0031083///BLOC-1 complex+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044297///cell body+++GO:0098793///presynapse+++GO:0098892///extrinsic component of postsynaptic specialization membrane "GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0007032///endosome organization+++GO:0030155///regulation of cell adhesion+++GO:0032012///regulation of ARF protein signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:2000171///negative regulation of dendrite development 19159 19159 'Cyth3' mRNA 1165 1162 1181 16.86 16.53 18.16 16.46 14.08 15.27 17.18333333 15.27 1307 1093 1174 1169.333333 1191.333333 0.918150089 0.012548152 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane "GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding" GO:0032012///regulation of ARF protein signal transduction+++GO:0045785///positive regulation of cell adhesion+++GO:0048193///Golgi vesicle transport+++GO:0050790///regulation of catalytic activity+++GO:0090162///establishment of epithelial cell polarity 19164 19164 'Psen1' mRNA 2235 2090 2217 46.01 42.35 48.42 47.28 47.81 46.67 45.59333333 47.25333333 2642 2609 2525 2180.666667 2592 0.002209224 0.235840619 04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04361///Axon regeneration+++04722///Neurotrophin signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0000776///kinetochore+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016235///aggresome+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0031901///early endosome membrane+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0035253///ciliary rootlet+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043227///membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070765///gamma-secretase complex+++GO:0097060///synaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0030165///PDZ domain binding+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0045296///cadherin binding+++GO:0051117///ATPase binding+++GO:0070851///growth factor receptor binding" "GO:0000045///autophagosome assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000186///activation of MAPKK activity+++GO:0001568///blood vessel development+++GO:0001708///cell fate specification+++GO:0001756///somitogenesis+++GO:0001764///neuron migration+++GO:0001921///positive regulation of receptor recycling+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001947///heart looping+++GO:0002038///positive regulation of L-glutamate import across plasma membrane+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002265///astrocyte activation involved in immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002573///myeloid leukocyte differentiation+++GO:0003407///neural retina development+++GO:0006469///negative regulation of protein kinase activity+++GO:0006486///protein glycosylation+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006816///calcium ion transport+++GO:0006839///mitochondrial transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007155///cell adhesion+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010975///regulation of neuron projection development+++GO:0015031///protein transport+++GO:0015871///choline transport+++GO:0016080///synaptic vesicle targeting+++GO:0016485///protein processing+++GO:0021549///cerebellum development+++GO:0021795///cerebral cortex cell migration+++GO:0021870///Cajal-Retzius cell differentiation+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030900///forebrain development+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034205///amyloid-beta formation+++GO:0035282///segmentation+++GO:0035556///intracellular signal transduction+++GO:0040011///locomotion+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042325///regulation of phosphorylation+++GO:0042327///positive regulation of phosphorylation+++GO:0042640///anagen+++GO:0042982///amyloid precursor protein metabolic process+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043393///regulation of protein binding+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043589///skin morphogenesis+++GO:0044267///cellular protein metabolic process+++GO:0045821///positive regulation of glycolytic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048143///astrocyte activation+++GO:0048167///regulation of synaptic plasticity+++GO:0048538///thymus development+++GO:0048666///neuron development+++GO:0048705///skeletal system morphogenesis+++GO:0048854///brain morphogenesis+++GO:0050435///amyloid-beta metabolic process+++GO:0050673///epithelial cell proliferation+++GO:0050771///negative regulation of axonogenesis+++GO:0050808///synapse organization+++GO:0050820///positive regulation of coagulation+++GO:0050852///T cell receptor signaling pathway+++GO:0051208///sequestering of calcium ion+++GO:0051402///neuron apoptotic process+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051563///smooth endoplasmic reticulum calcium ion homeostasis+++GO:0051604///protein maturation+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060075///regulation of resting membrane potential+++GO:0060291///long-term synaptic potentiation+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0060999///positive regulation of dendritic spine development+++GO:0070588///calcium ion transmembrane transport+++GO:0090647///modulation of age-related behavioral decline+++GO:0098609///cell-cell adhesion+++GO:0098712///L-glutamate import across plasma membrane+++GO:1904646///cellular response to amyloid-beta+++GO:1904797///negative regulation of core promoter binding+++GO:1905908///positive regulation of amyloid fibril formation+++GO:1990535///neuron projection maintenance+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2001234///negative regulation of apoptotic signaling pathway" 19165 19165 'Psen2' mRNA 841 847 815 23.97 23.79 24.64 26.95 26.87 26.31 24.13333333 26.71 1087 1058 1027 834.3333333 1057.333333 2.75E-04 0.329928278 04330///Notch signaling pathway+++04722///Neurotrophin signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000139///Golgi membrane+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0035253///ciliary rootlet+++GO:0036064///ciliary basal body+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0070765///gamma-secretase complex+++GO:0097060///synaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016787///hydrolase activity+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001708///cell fate specification+++GO:0001756///somitogenesis+++GO:0001921///positive regulation of receptor recycling+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002286///T cell activation involved in immune response+++GO:0002573///myeloid leukocyte differentiation+++GO:0006486///protein glycosylation+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0006816///calcium ion transport+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0009790///embryo development+++GO:0015031///protein transport+++GO:0016485///protein processing+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0030326///embryonic limb morphogenesis+++GO:0030900///forebrain development+++GO:0031333///negative regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032635///interleukin-6 production+++GO:0032640///tumor necrosis factor production+++GO:0034205///amyloid-beta formation+++GO:0035556///intracellular signal transduction+++GO:0040011///locomotion+++GO:0042640///anagen+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043393///regulation of protein binding+++GO:0043589///skin morphogenesis+++GO:0044267///cellular protein metabolic process+++GO:0048167///regulation of synaptic plasticity+++GO:0048286///lung alveolus development+++GO:0048538///thymus development+++GO:0048854///brain morphogenesis+++GO:0050435///amyloid-beta metabolic process+++GO:0050820///positive regulation of coagulation+++GO:0050852///T cell receptor signaling pathway+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051604///protein maturation+++GO:0060048///cardiac muscle contraction+++GO:0070050///neuron cellular homeostasis+++GO:0097502///mannosylation+++GO:0110097///regulation of calcium import into the mitochondrion+++GO:0150076///neuroinflammatory response+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2001234///negative regulation of apoptotic signaling pathway 19166 19166 'Psma2' mRNA 2992 3244 2882 205.09 220.02 209.62 274.64 292.51 269.52 211.5766667 278.89 4592 4766 4354 3039.333333 4570.666667 1.98E-19 0.578530509 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex" GO:0004175///endopeptidase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009615///response to virus+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19167 19167 'Psma3' mRNA 4327.92 4346.75 4463.33 207.53 205.08 215.46 275.93 279.66 270.25 209.3566667 275.28 6258.56 6108.78 5906.37 4379.333333 6091.236667 1.99E-13 0.462537323 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0045202///synapse" GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0052548///regulation of endopeptidase activity 19170 19170 'Psmb1' mRNA 2855 2705 2744 174.7 163.64 178.16 226.57 225.74 222.94 172.1666667 225.0833333 4246 4124 4038 2768 4136 3.18E-19 0.566749427 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19171 19171 'Psmb10' mRNA 655 671 671 31.34 31.69 34.06 73.81 78.02 74.12 32.36333333 75.31666667 1771 1826 1720 665.6666667 1772.333333 3.88E-61 1.400678957 03050///Proteasome "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:1990111///spermatoproteasome complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0000902///cell morphogenesis+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0042098///T cell proliferation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19172 19172 'Psmb4' mRNA 2376 2479 2401 162.21 167.46 173.94 235.06 218.17 244.21 167.87 232.48 3946 3569 3961 2418.666667 3825.333333 1.18E-22 0.648553769 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:0036064///ciliary basal body" GO:0001530///lipopolysaccharide binding+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19173 19173 'Psmb5' mRNA 2566 2620 2547 195.47 197.64 205.89 284.72 287.22 289.14 199.6666667 287.0266667 4281 4207 4199 2577.666667 4229 1.46E-31 0.702163813 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006979///response to oxidative stress+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19175 19175 'Psmb6' mRNA 4014 4062 3992 245.69 245.94 259.39 309.92 335.2 312 250.34 319.04 5804 6118 5649 4022.666667 5857 4.61E-17 0.530214663 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0003713///transcription coactivator activity+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity GO:0006338///chromatin remodeling+++GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051603///proteolysis involved in cellular protein catabolic process 19177 19177 'Psmb7' mRNA 2259 2321 2051 155.73 158.72 150 183.19 187.27 180.46 154.8166667 183.64 3018 3036 2899 2210.333333 2984.333333 4.37E-11 0.423300006 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0016604///nuclear body+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 19179 19179 'Psmc1' mRNA 2675 2980 2869 105.22 115.61 119.72 131.04 133.81 134.61 113.5166667 133.1533333 3827 3813 3803 2841.333333 3814.333333 2.58E-09 0.412335491 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0016020///membrane+++GO:0022624///proteasome accessory complex" GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0036402///proteasome-activating ATPase activity GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1901215///negative regulation of neuron death+++GO:1901800///positive regulation of proteasomal protein catabolic process 19181 19181 'Psmc2' mRNA 1811 1912 1792 73.77 76.92 77.4 97.5 102.59 97.18 76.03 99.09 2749 2833 2655 1838.333333 2745.666667 2.11E-16 0.567596211 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0022624///proteasome accessory complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043197///dendritic spine" GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016887///ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0036402///proteasome-activating ATPase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:1901800///positive regulation of proteasomal protein catabolic process 19182 19182 'Psmc3' mRNA 3946 3920 3669 140.85 137.96 138.94 152.97 161.61 155.97 139.25 156.85 4924 5077 4858 3845 4953 1.32E-09 0.354718635 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0022624///proteasome accessory complex+++GO:0048471///perinuclear region of cytoplasm" GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0036402///proteasome-activating ATPase activity+++GO:0042802///identical protein binding GO:0001824///blastocyst development+++GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043921///modulation by host of viral transcription+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901800///positive regulation of proteasomal protein catabolic process 19183 19183 'Psmc3ip' mRNA 450.27 476.69 452.88 24.68 25.51 25.73 15.76 13.93 16.14 25.30666667 15.27666667 350.88 287.12 341.76 459.9466667 326.5866667 1.89E-04 -0.507676724 GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035259///glucocorticoid receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0050681///androgen receptor binding+++GO:0050692///DBD domain binding "GO:0000709///meiotic joint molecule formation+++GO:0006310///DNA recombination+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0010774///meiotic strand invasion involved in reciprocal meiotic recombination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051321///meiotic cell cycle" 19184 19184 'Psmc5' mRNA 2883 3060 2923 137.03 143.58 147.4 167.65 170.73 174.6 142.67 170.9933333 4049 4022 4078 2955.333333 4049.666667 1.07E-12 0.442590705 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005675///transcription factor TFIIH holo complex+++GO:0005737///cytoplasm+++GO:0005838///proteasome regulatory particle+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0016234///inclusion body+++GO:0022624///proteasome accessory complex+++GO:0031410///cytoplasmic vesicle+++GO:0031595///nuclear proteasome complex+++GO:0031597///cytosolic proteasome complex+++GO:0098794///postsynapse" GO:0000166///nucleotide binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016887///ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0031531///thyrotropin-releasing hormone receptor binding+++GO:0036402///proteasome-activating ATPase activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0050804///modulation of chemical synaptic transmission+++GO:0090261///positive regulation of inclusion body assembly+++GO:1901800///positive regulation of proteasomal protein catabolic process" 19185 19185 'Psmd4' mRNA 2926 2985 2950 131.76 132.62 140.9 161.12 172.76 172.36 135.0933333 168.7466667 4112 4301 4253 2953.666667 4222 1.32E-14 0.503516488 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0022624///proteasome accessory complex" GO:0008134///transcription factor binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043248///proteasome assembly 19186 19186 'Psme1' mRNA 1890 1899 1801 124.4 123.64 125.78 189.31 186.05 195.79 124.6066667 190.3833333 3297 3158 3295 1863.333333 3250 8.84E-37 0.79104117 03050///Proteasome+++04612///Antigen processing and presentation GO:0000502///proteasome complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008537///proteasome activator complex GO:0005515///protein binding+++GO:0061133///endopeptidase activator activity GO:0010950///positive regulation of endopeptidase activity+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 19188 19188 'Psme2' mRNA 1729.84 1932.02 1737.74 129.38 144.8 138.54 265.37 283.36 262.96 137.5733333 270.5633333 4104.54 4256.08 3949.43 1799.866667 4103.35 5.06E-67 1.178621907 03050///Proteasome+++04612///Antigen processing and presentation GO:0000502///proteasome complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008537///proteasome activator complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0061133///endopeptidase activator activity GO:0010950///positive regulation of endopeptidase activity+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 19192 19192 'Psme3' mRNA 989 978 257 20.53 19.97 5.65 8.38 8.47 11.21 15.38333333 9.353333333 467 460 602 741.3333333 509.6666667 0.454849865 -0.52587906 03050///Proteasome+++04612///Antigen processing and presentation+++05160///Hepatitis C GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008537///proteasome activator complex GO:0002039///p53 binding+++GO:0008233///peptidase activity+++GO:0042802///identical protein binding+++GO:0061133///endopeptidase activator activity+++GO:0097371///MDM2/MDM4 family protein binding GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0010950///positive regulation of endopeptidase activity+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 19193 19193 'Pipox' mRNA 166 227 196 5.43 7.32 6.84 11.38 11.54 10.38 6.53 11.1 400 397 354 196.3333333 383.6666667 3.80E-09 0.954985764 "00260///Glycine, serine and threonine metabolism+++00310///Lysine degradation+++04146///Peroxisome" GO:0005777///peroxisome GO:0008115///sarcosine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050031///L-pipecolate oxidase activity GO:0033514///L-lysine catabolic process to acetyl-CoA via L-pipecolate+++GO:0046653///tetrahydrofolate metabolic process 19194 19194 'Bpifa2' mRNA 2 7 7 0.13 0.47 0.5 0.47 0.24 0.3 0.366666667 0.336666667 8 4 5 5.333333333 5.666666667 0.967990393 0.062643429 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule GO:0001530///lipopolysaccharide binding+++GO:0008289///lipid binding GO:0008150///biological_process+++GO:0042742///defense response to bacterium 19197 19197 'Pspn' mRNA 3 6 4 0.3 0.6 0.43 0.18 0.45 0.27 0.443333333 0.3 2 5 3 4.333333333 3.333333333 0.826670417 -0.38035912 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0008083///growth factor activity+++GO:0030116///glial cell-derived neurotrophic factor receptor binding+++GO:0030971///receptor tyrosine kinase binding GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0007165///signal transduction 19200 19200 'Pstpip1' mRNA 77 67 78 3.07 2.65 3.17 18.14 15.64 15.94 2.963333333 16.57333333 544 462 460 74 488.6666667 2.81E-56 2.708718874 04621///NOD-like receptor signaling pathway GO:0001725///stress fiber+++GO:0001931///uropod+++GO:0005737///cytoplasm+++GO:0005826///actomyosin contractile ring+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0032154///cleavage furrow+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0000910///cytokinesis+++GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0030041///actin filament polymerization+++GO:0045087///innate immune response 19201 19201 'Pstpip2' mRNA 147 96 117 2.58 1.67 2.26 5.72 5.78 5.27 2.17 5.59 377 367 333 120 359 1.33E-17 1.568116759 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0016477///cell migration+++GO:0030041///actin filament polymerization 19204 19204 'Ptafr' mRNA 90 107 95 1.34 1.57 1.5 19.51 19.79 20.19 1.47 19.83 1505 1491 1508 97.33333333 1501.333333 4.12E-228 3.936457098 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++05150///Staphylococcus aureus infection GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001530///lipopolysaccharide binding+++GO:0001875///lipopolysaccharide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004992///platelet activating factor receptor activity+++GO:0005543///phospholipid binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0051019///mitogen-activated protein kinase binding GO:0001816///cytokine production+++GO:0002693///positive regulation of cellular extravasation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007567///parturition+++GO:0009609///response to symbiotic bacterium+++GO:0010863///positive regulation of phospholipase C activity+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0045056///transcytosis+++GO:0045727///positive regulation of translation+++GO:0045776///negative regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046683///response to organophosphorus+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0071258///cellular response to gravity+++GO:0071320///cellular response to cAMP+++GO:0071398///cellular response to fatty acid+++GO:0071548///response to dexamethasone+++GO:1902943///positive regulation of voltage-gated chloride channel activity+++GO:1903039///positive regulation of leukocyte cell-cell adhesion+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1904058///positive regulation of sensory perception of pain+++GO:1904300///positive regulation of transcytosis+++GO:1904303///positive regulation of maternal process involved in parturition+++GO:1904306///positive regulation of gastro-intestinal system smooth muscle contraction+++GO:1904316///response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine+++GO:1904317///cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 19205 19205 'Ptbp1' mRNA 5969.61 6042.18 5791.53 106.75 106.16 109.7 84.56 76.88 85.31 107.5366667 82.25 5450.63 4831.45 5327.46 5934.44 5203.18 9.31E-04 -0.202387065 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0044306///neuron projection terminus GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0001069///regulatory region RNA binding+++GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding+++GO:0043565///sequence-specific DNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006259///DNA metabolic process+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010467///gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0022008///neurogenesis+++GO:0032024///positive regulation of insulin secretion+++GO:0033119///negative regulation of RNA splicing+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0075522///IRES-dependent viral translational initiation+++GO:1904411///positive regulation of secretory granule organization" 19206 19206 'Ptch1' mRNA 598 629 548 4.32 4.46 4.2 2.38 2.29 2.37 4.326666667 2.346666667 379 357 367 591.6666667 367.6666667 1.84E-09 -0.696610038 04024///cAMP signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04360///Axon guidance+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0005113///patched binding+++GO:0005119///smoothened binding+++GO:0005515///protein binding+++GO:0008158///hedgehog receptor activity+++GO:0008201///heparin binding+++GO:0008270///zinc ion binding+++GO:0015485///cholesterol binding+++GO:0030332///cyclin binding+++GO:0044877///protein-containing complex binding+++GO:0097108///hedgehog family protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001709///cell fate determination+++GO:0001841///neural tube formation+++GO:0001843///neural tube closure+++GO:0003007///heart morphogenesis+++GO:0007165///signal transduction+++GO:0007224///smoothened signaling pathway+++GO:0007346///regulation of mitotic cell cycle+++GO:0007389///pattern specification process+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0009612///response to mechanical stimulus+++GO:0009887///animal organ morphogenesis+++GO:0009953///dorsal/ventral pattern formation+++GO:0009957///epidermal cell fate specification+++GO:0010157///response to chlorate+++GO:0010875///positive regulation of cholesterol efflux+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021532///neural tube patterning+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021997///neural plate axis specification+++GO:0030326///embryonic limb morphogenesis+++GO:0030850///prostate gland development+++GO:0030879///mammary gland development+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032880///regulation of protein localization+++GO:0035108///limb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0040008///regulation of growth+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043616///keratinocyte proliferation+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048568///embryonic organ development+++GO:0048745///smooth muscle tissue development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051782///negative regulation of cell division+++GO:0060037///pharyngeal system development+++GO:0060603///mammary gland duct morphogenesis+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0061005///cell differentiation involved in kidney development+++GO:0061053///somite development+++GO:0071397///cellular response to cholesterol+++GO:0071679///commissural neuron axon guidance+++GO:0072203///cell proliferation involved in metanephros development+++GO:0072205///metanephric collecting duct development+++GO:0072659///protein localization to plasma membrane+++GO:0097421///liver regeneration" 19207 19207 'Ptch2' mRNA 15 20 32 0.16 0.21 0.35 0.37 0.23 0.29 0.24 0.296666667 41 25 31 22.33333333 32.33333333 0.395099436 0.505084901 04340///Hedgehog signaling pathway+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005119///smoothened binding+++GO:0008158///hedgehog receptor activity+++GO:0097108///hedgehog family protein binding GO:0001558///regulation of cell growth+++GO:0001709///cell fate determination+++GO:0007224///smoothened signaling pathway+++GO:0008544///epidermis development+++GO:0009957///epidermal cell fate specification+++GO:0042633///hair cycle+++GO:0043588///skin development+++GO:0045606///positive regulation of epidermal cell differentiation 19208 19208 'Ptcra' mRNA 14.28 12.94 14.67 0.67 0.6 0.74 1.21 1.64 1.09 0.67 1.313333333 29.38 38.81 25.6 13.96333333 31.26333333 0.034432571 1.189920219 04330///Notch signaling pathway+++05202///Transcriptional misregulation in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0070244///negative regulation of thymocyte apoptotic process 19210 19210 'Ptdss1' mRNA 1839 1752.98 1757.61 29.25 27.43 29.65 28.34 26.91 28.31 28.77666667 27.85333333 2050.99 1902 1984 1783.196667 1978.996667 0.082572208 0.137813073 00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0008654///phospholipid biosynthetic process 19211 19211 'Pten' mRNA 676.9 550 541 4.35 3.47 3.69 4.21 3.45 4.18 3.836666667 3.946666667 754 604.96 726 589.3 694.9866667 0.093162491 0.226084001 00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04115///p53 signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04361///Axon regeneration+++04510///Focal adhesion+++04931///Insulin resistance+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05222///Small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05230///Central carbon metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016605///PML body+++GO:0035749///myelin sheath adaxonal region+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043220///Schmidt-Lanterman incisure+++GO:0045211///postsynaptic membrane+++GO:0099524///postsynaptic cytosol "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0010997///anaphase-promoting complex binding+++GO:0016314///phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0051717///inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity+++GO:0051800///phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity+++GO:1990381///ubiquitin-specific protease binding+++GO:1990782///protein tyrosine kinase binding" "GO:0001525///angiogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002902///regulation of B cell apoptotic process+++GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0006915///apoptotic process+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0010043///response to zinc ion+++GO:0010628///positive regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010975///regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0016311///dephosphorylation+++GO:0016477///cell migration+++GO:0021542///dentate gyrus development+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030336///negative regulation of cell migration+++GO:0030534///adult behavior+++GO:0031175///neuron projection development+++GO:0031642///negative regulation of myelination+++GO:0031647///regulation of protein stability+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0032286///central nervous system myelin maintenance+++GO:0032355///response to estradiol+++GO:0032535///regulation of cellular component size+++GO:0032869///cellular response to insulin stimulus+++GO:0033032///regulation of myeloid cell apoptotic process+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0033198///response to ATP+++GO:0033555///multicellular organismal response to stress+++GO:0035176///social behavior+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0036294///cellular response to decreased oxygen levels+++GO:0042493///response to drug+++GO:0042711///maternal behavior+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0043542///endothelial cell migration+++GO:0044320///cellular response to leptin stimulus+++GO:0045471///response to ethanol+++GO:0045475///locomotor rhythm+++GO:0045666///positive regulation of neuron differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045792///negative regulation of cell size+++GO:0046621///negative regulation of organ growth+++GO:0046685///response to arsenic-containing substance+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048679///regulation of axon regeneration+++GO:0048681///negative regulation of axon regeneration+++GO:0048738///cardiac muscle tissue development+++GO:0048853///forebrain morphogenesis+++GO:0048854///brain morphogenesis+++GO:0048870///cell motility+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050765///negative regulation of phagocytosis+++GO:0050771///negative regulation of axonogenesis+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051548///negative regulation of keratinocyte migration+++GO:0051726///regulation of cell cycle+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0051896///regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060024///rhythmic synaptic transmission+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060074///synapse maturation+++GO:0060134///prepulse inhibition+++GO:0060179///male mating behavior+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0060341///regulation of cellular localization+++GO:0060736///prostate gland growth+++GO:0060997///dendritic spine morphogenesis+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071257///cellular response to electrical stimulus+++GO:0071361///cellular response to ethanol+++GO:0071456///cellular response to hypoxia+++GO:0090071///negative regulation of ribosome biogenesis+++GO:0090344///negative regulation of cell aging+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0097105///presynaptic membrane assembly+++GO:0097107///postsynaptic density assembly+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:1903984///positive regulation of TRAIL-activated apoptotic signaling pathway+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000808///negative regulation of synaptic vesicle clustering+++GO:2001235///positive regulation of apoptotic signaling pathway" 192113 192113 'Atp12a' mRNA 0 1 0 0 0.01 0 0.01 0 0.01 0.003333333 0.006666667 1 0 1 0.333333333 0.666666667 0.863090843 0.873430513 00190///Oxidative phosphorylation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0000166///nucleotide binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0008900///potassium:proton exchanging ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0006885///regulation of pH+++GO:0010038///response to metal ion+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0014070///response to organic cyclic compound+++GO:0030007///cellular potassium ion homeostasis+++GO:0036376///sodium ion export across plasma membrane+++GO:0055075///potassium ion homeostasis+++GO:1902600///proton transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 192119 192119 'Dicer1' mRNA 706 724 596 3.78 3.81 3.41 2.83 2.61 2.56 3.666666667 2.666666667 605 547 532 675.3333333 561.3333333 0.01647029 -0.276096051 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0016442///RISC complex+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0070578///RISC-loading complex "GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004525///ribonuclease III activity+++GO:0004530///deoxyribonuclease I activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0019904///protein domain specific binding+++GO:0035197///siRNA binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0070883///pre-miRNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000212///meiotic spindle organization+++GO:0001525///angiogenesis+++GO:0001834///trophectodermal cell proliferation+++GO:0001932///regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0006309///apoptotic DNA fragmentation+++GO:0006396///RNA processing+++GO:0007284///spermatogonial cell division+++GO:0008283///cell proliferation+++GO:0008593///regulation of Notch signaling pathway+++GO:0009791///post-embryonic development+++GO:0010070///zygote asymmetric cell division+++GO:0010468///regulation of gene expression+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010660///regulation of muscle cell apoptotic process+++GO:0014040///positive regulation of Schwann cell differentiation+++GO:0014835///myoblast differentiation involved in skeletal muscle regeneration+++GO:0016075///rRNA catabolic process+++GO:0016246///RNA interference+++GO:0019827///stem cell population maintenance+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021675///nerve development+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0021987///cerebral cortex development+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030422///production of siRNA involved in RNA interference+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0031069///hair follicle morphogenesis+++GO:0031508///pericentric heterochromatin assembly+++GO:0031641///regulation of myelination+++GO:0031643///positive regulation of myelination+++GO:0032290///peripheral nervous system myelin formation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033168///conversion of ds siRNA to ss siRNA involved in RNA interference+++GO:0035087///siRNA loading onto RISC involved in RNA interference+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035264///multicellular organism growth+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0036404///conversion of ds siRNA to ss siRNA+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0045069///regulation of viral genome replication+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048255///mRNA stabilization+++GO:0048536///spleen development+++GO:0048565///digestive tract development+++GO:0048608///reproductive structure development+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0048730///epidermis morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048812///neuron projection morphogenesis+++GO:0048856///anatomical structure development+++GO:0050727///regulation of inflammatory response+++GO:0050767///regulation of neurogenesis+++GO:0051216///cartilage development+++GO:0051225///spindle assembly+++GO:0051252///regulation of RNA metabolic process+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0055013///cardiac muscle cell development+++GO:0060119///inner ear receptor cell development+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060576///intestinal epithelial cell development+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0061548///ganglion development+++GO:0070173///regulation of enamel mineralization+++GO:0071335///hair follicle cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:1904899///positive regulation of hepatic stellate cell proliferation+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000628///regulation of miRNA metabolic process+++GO:2000630///positive regulation of miRNA metabolic process+++GO:2000736///regulation of stem cell differentiation" 19212 19212 'Pter' mRNA 143.51 111.91 131.22 2.14 1.62 2.07 1.84 1.57 1.94 1.943333333 1.783333333 141.73 120.25 146.35 128.88 136.11 0.841938349 0.065601211 "GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding" GO:0009056///catabolic process+++GO:0030855///epithelial cell differentiation 192120 192120 'Bspry' mRNA 139 118 110 3.66 3.05 3.07 2.86 3.04 2.88 3.26 2.926666667 123 129 122 122.3333333 124.6666667 0.954227407 0.017970083 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm GO:0005499///vitamin D binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0016567///protein ubiquitination+++GO:1990830///cellular response to leukemia inhibitory factor 192136 192136 'Sugct' mRNA 152 142 118 5.21 4.83 4.27 0.72 0.61 0.54 4.77 0.623333333 24 20 17 137.3333333 20.33333333 8.57E-19 -2.764872788 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008410///CoA-transferase activity+++GO:0016740///transferase activity+++GO:0047369///succinate-hydroxymethylglutarate CoA-transferase activity 19214 19214 'Ptgdr' mRNA 4 14 9 0.07 0.24 0.16 3.49 4.54 3.93 0.156666667 3.986666667 234 297 255 9 262 3.73E-43 4.85556751 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001785///prostaglandin J receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004956///prostaglandin D receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0030238///male sex determination+++GO:0030431///sleep+++GO:0043303///mast cell degranulation+++GO:0046085///adenosine metabolic process+++GO:0071799///cellular response to prostaglandin D stimulus 192140 192140 'Tmc2' mRNA 308.23 316 287.66 5.24 5.29 5.19 0.18 0.32 0.44 5.24 0.313333333 12.44 21 29 303.9633333 20.81333333 8.35E-49 -3.885790494 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032426///stereocilium tip GO:0005245///voltage-gated calcium channel activity+++GO:0005515///protein binding+++GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060005///vestibular reflex+++GO:0070588///calcium ion transmembrane transport+++GO:1903169///regulation of calcium ion transmembrane transport 19215 19215 'Ptgds' mRNA 641390 638300 582996 53104.64 52371.81 51201.3 20864.2 20285.88 20758.02 52225.91667 20636.03333 288882 273735 277568 620895.3333 280061.6667 2.24E-180 -1.159393286 00590///Arachidonic acid metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004667///prostaglandin-D synthase activity+++GO:0005501///retinoid binding+++GO:0005504///fatty acid binding+++GO:0016853///isomerase activity+++GO:0036094///small molecule binding "GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0043303///mast cell degranulation+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0051384///response to glucocorticoid+++GO:2000255///negative regulation of male germ cell proliferation" 192156 192156 'Mvd' mRNA 470 507 459 15.42 16.4 15.98 14.88 15.68 13.01 15.93333333 14.52333333 521 536 441 478.6666667 499.3333333 0.770718701 0.050134866 00900///Terpenoid backbone biosynthesis GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004163///diphosphomevalonate decarboxylase activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030544///Hsp70 protein binding+++GO:0042803///protein homodimerization activity "GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008299///isoprenoid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0019287///isopentenyl diphosphate biosynthetic process, mevalonate pathway" 192157 192157 'Socs7' mRNA 526 450 452 3.91 3.3 3.58 2.97 2.84 3.13 3.596666667 2.98 461 427 469 476 452.3333333 0.595138134 -0.085192368 04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0008286///insulin receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021819///layer formation in cerebral cortex+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0045444///fat cell differentiation+++GO:0046854///phosphatidylinositol phosphorylation 192159 192159 'Prpf8' mRNA 3538 3477 3208 24.93 24.08 23.97 17.73 14.71 16.77 24.32666667 16.40333333 2898 2350 2656 3407.666667 2634.666667 1.69E-07 -0.383438167 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0016607///nuclear speck+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding+++GO:0008237///metallopeptidase activity+++GO:0017070///U6 snRNA binding+++GO:0030619///U1 snRNA binding+++GO:0030620///U2 snRNA binding+++GO:0030623///U5 snRNA binding+++GO:0070122///isopeptidase activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0097157///pre-mRNA intronic binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006508///proteolysis+++GO:0008380///RNA splicing+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor" 19216 19216 'Ptger1' mRNA 87.53 157.56 84.67 0.8 1.47 0.88 1.26 1.42 1.21 1.05 1.296666667 151.56 174.4 147.34 109.92 157.7666667 0.058867405 0.523269502 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004955///prostaglandin receptor activity+++GO:0004957///prostaglandin E receptor activity+++GO:0031748///D1 dopamine receptor binding GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0032496///response to lipopolysaccharide+++GO:0120061///negative regulation of gastric emptying 192160 192160 'Casc3' mRNA 1126 1237 402 16.3 17.62 6.17 5.47 5.92 6.36 13.36333333 5.916666667 435 460 490 921.6666667 461.6666667 0.047873774 -0.985729112 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0035145///exon-exon junction complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0008298///intracellular mRNA localization+++GO:0008380///RNA splicing+++GO:0051028///mRNA transport" 192161 192161 'Pcdha9' mRNA 59.18 58.59 66.07 0.59 0.57 0.7 0 0 0 0.62 0 0 0 0 61.28 0 6.53E-11 -8.388970822 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 192163 192163 'Pcdha3' mRNA 5.35 15.56 2.11 0.05 0.15 0.02 0 0 0 0.073333333 0 0 0 0 7.673333333 0 0.00466907 -5.298773889 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 192164 192164 'Pcdha12' mRNA 111.54 179.23 89.13 1.13 1.79 0.96 0.09 0.15 0.16 1.293333333 0.133333333 10.02 16.83 17.26 126.6333333 14.70333333 2.48E-16 -3.137627469 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 192166 192166 'Sardh' mRNA 300 310 316 3.71 3.64 4.11 3.12 2.96 2.97 3.82 3.016666667 299 273 262 308.6666667 278 0.346802398 -0.164783896 "00260///Glycine, serine and threonine metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0005542///folic acid binding+++GO:0008480///sarcosine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0035999///tetrahydrofolate interconversion+++GO:1901053///sarcosine catabolic process 192167 192167 'Nlgn1' mRNA 131 113 128 0.42 0.36 0.44 0.07 0.05 0.04 0.406666667 0.053333333 24 18 14 124 18.66666667 1.50E-16 -2.747891055 04514///Cell adhesion molecules GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032433///filopodium tip+++GO:0043083///synaptic cleft+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0038023///signaling receptor activity+++GO:0042043///neurexin family protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding+++GO:0097110///scaffold protein binding "GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006605///protein targeting+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007158///neuron cell-cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0010841///positive regulation of circadian sleep/wake cycle, wakefulness+++GO:0016080///synaptic vesicle targeting+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0031175///neuron projection development+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0035418///protein localization to synapse+++GO:0045184///establishment of protein localization+++GO:0045664///regulation of neuron differentiation+++GO:0048488///synaptic vesicle endocytosis+++GO:0048489///synaptic vesicle transport+++GO:0048511///rhythmic process+++GO:0048789///cytoskeletal matrix organization at active zone+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0051491///positive regulation of filopodium assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060080///inhibitory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0060999///positive regulation of dendritic spine development+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0071277///cellular response to calcium ion+++GO:0072553///terminal button organization+++GO:0097091///synaptic vesicle clustering+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0097113///AMPA glutamate receptor clustering+++GO:0097114///NMDA glutamate receptor clustering+++GO:0097115///neurexin clustering involved in presynaptic membrane assembly+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0097120///receptor localization to synapse+++GO:0098698///postsynaptic specialization assembly+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0099174///regulation of presynapse organization+++GO:0099560///synaptic membrane adhesion+++GO:0140058///neuron projection arborization+++GO:1900029///positive regulation of ruffle assembly+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1902474///positive regulation of protein localization to synapse+++GO:1902533///positive regulation of intracellular signal transduction+++GO:1904861///excitatory synapse assembly+++GO:1905520///positive regulation of presynaptic active zone assembly+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000809///positive regulation of synaptic vesicle clustering" 192169 192169 'Ufsp2' mRNA 623 694 717 22.29 25.09 27.47 29.49 35.18 30.16 24.95 31.61 950 1105 931 678 995.3333333 3.62E-06 0.541070973 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0071567///UFM1 hydrolase activity GO:0006508///proteolysis+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway 19217 19217 'Ptger2' mRNA 5 3 2 0.08 0.04 0.03 1.15 1.48 1.79 0.05 1.473333333 90 116 134 3.333333333 113.3333333 1.17E-19 5.081665556 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels+++04924///Renin secretion+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004957///prostaglandin E receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0042127///regulation of cell proliferation+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:1904346///positive regulation of gastric mucosal blood circulation 192170 192170 'Eif4a3' mRNA 1767 1879 1853 71.64 75.15 79.71 94.75 93.81 95.61 75.5 94.72333333 2684 2593.02 2620 1833 2632.34 7.13E-13 0.509243201 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0035145///exon-exon junction complex+++GO:0043025///neuronal cell body+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008143///poly(A) binding+++GO:0016787///hydrolase activity+++GO:0035368///selenocysteine insertion sequence binding+++GO:0035613///RNA stem-loop binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0045182///translation regulator activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0008380///RNA splicing+++GO:0010629///negative regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0051028///mRNA transport+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:1902415///regulation of mRNA binding+++GO:1904570///negative regulation of selenocysteine incorporation+++GO:1904574///negative regulation of selenocysteine insertion sequence binding" 192173 192173 'Mcrip1' mRNA 2842 2883 2253 143.71 144.56 121.27 112.33 139.56 127.5 136.5133333 126.4633333 2540 3073 2786 2659.333333 2799.666667 0.549730988 0.069335735 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0003674///molecular_function GO:0010717///regulation of epithelial to mesenchymal transition 192174 192174 'Rwdd4a' mRNA 692 704 625 12.89 12.91 12.35 12.37 10.54 12.07 12.71666667 11.66 764 636 722 673.6666667 707.3333333 0.672120186 0.059034202 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 192176 192176 'Flna' mRNA 4804 5123 4523 30.23 31.56 30.06 55.17 52.88 54.14 30.61666667 54.06333333 10120 9461 9624 4816.666667 9735 1.41E-87 1.004431718 04010///MAPK signaling pathway+++04510///Focal adhesion+++05132///Salmonella infection+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0030426///growth cone+++GO:0030863///cortical cytoskeleton+++GO:0031523///Myb complex+++GO:0032432///actin filament bundle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0001664///G protein-coupled receptor binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0015459///potassium channel regulator activity+++GO:0019900///kinase binding+++GO:0031267///small GTPase binding+++GO:0031852///mu-type opioid receptor binding+++GO:0034988///Fc-gamma receptor I complex binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046332///SMAD binding+++GO:0051015///actin filament binding+++GO:0051020///GTPase binding "GO:0001525///angiogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0007195///adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:0016479///negative regulation of transcription by RNA polymerase I+++GO:0021943///formation of radial glial scaffolds+++GO:0021987///cerebral cortex development+++GO:0030030///cell projection organization+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0032231///regulation of actin filament bundle assembly+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0034394///protein localization to cell surface+++GO:0042177///negative regulation of protein catabolic process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043066///negative regulation of apoptotic process+++GO:0043113///receptor clustering+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0044319///wound healing, spreading of cells+++GO:0045022///early endosome to late endosome transport+++GO:0045184///establishment of protein localization+++GO:0045216///cell-cell junction organization+++GO:0048680///positive regulation of axon regeneration+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0051220///cytoplasmic sequestering of protein+++GO:0051764///actin crosslink formation+++GO:0060271///cilium assembly+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0090042///tubulin deacetylation+++GO:0090307///mitotic spindle assembly+++GO:0097368///establishment of Sertoli cell barrier+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1902396///protein localization to bicellular tight junction+++GO:1905000///regulation of membrane repolarization during atrial cardiac muscle cell action potential+++GO:1905031///regulation of membrane repolarization during cardiac muscle cell action potential+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2001046///positive regulation of integrin-mediated signaling pathway+++GO:2001224///positive regulation of neuron migration" 19218 19218 'Ptger3' mRNA 22 20 15 0.72 0.53 0.54 0.8 0.57 0.91 0.596666667 0.76 33 20 37 19 30 0.260990504 0.649840491 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04923///Regulation of lipolysis in adipocytes+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0031965///nuclear membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:1990769///proximal neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0004955///prostaglandin receptor activity+++GO:0004957///prostaglandin E receptor activity+++GO:0005515///protein binding "GO:0001660///fever generation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010628///positive regulation of gene expression+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0010840///regulation of circadian sleep/wake cycle, wakefulness+++GO:0014061///regulation of norepinephrine secretion+++GO:0014827///intestine smooth muscle contraction+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0015701///bicarbonate transport+++GO:0031622///positive regulation of fever generation+++GO:0031623///receptor internalization+++GO:0032496///response to lipopolysaccharide+++GO:0035810///positive regulation of urine volume+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045907///positive regulation of vasoconstriction+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046676///negative regulation of insulin secretion+++GO:0060455///negative regulation of gastric acid secretion+++GO:0090331///negative regulation of platelet aggregation+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1903170///negative regulation of calcium ion transmembrane transport+++GO:1903640///negative regulation of gastrin-induced gastric acid secretion+++GO:1904320///positive regulation of smooth muscle contraction involved in micturition+++GO:1904322///cellular response to forskolin+++GO:1904325///positive regulation of inhibitory G protein-coupled receptor phosphorylation+++GO:1904326///negative regulation of circadian sleep/wake cycle, wakefulness+++GO:1904330///positive regulation of myofibroblast contraction+++GO:1904343///positive regulation of colon smooth muscle contraction+++GO:1904346///positive regulation of gastric mucosal blood circulation+++GO:1990767///prostaglandin receptor internalization+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000978///negative regulation of forebrain neuron differentiation" 192185 192185 'Nadk' mRNA 2525 2695 2659 45.85 48.09 51.43 65.64 68.01 62.7 48.45666667 65.45 4146 4178 3833 2626.333333 4052.333333 1.60E-18 0.61288333 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006741///NADP biosynthetic process+++GO:0016310///phosphorylation+++GO:0019674///NAD metabolic process+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus 192187 192187 'Stab1' mRNA 450 488 499 2.96 3.16 3.48 35.14 33.75 35.45 3.2 34.78 6138.83 5767.82 6001.82 479 5969.49 0 3.626239544 GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005509///calcium ion binding+++GO:0005540///hyaluronic acid binding+++GO:0030169///low-density lipoprotein particle binding GO:0006897///endocytosis+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007267///cell-cell signaling+++GO:0016525///negative regulation of angiogenesis+++GO:0042742///defense response to bacterium 192188 192188 'Stab2' mRNA 53 51 31 0.57 0.54 0.37 0.42 0.33 0.27 0.493333333 0.34 44 35 27 45 35.33333333 0.471677959 -0.353932557 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005509///calcium ion binding+++GO:0005540///hyaluronic acid binding+++GO:0030169///low-density lipoprotein particle binding GO:0006897///endocytosis+++GO:0007155///cell adhesion+++GO:0042742///defense response to bacterium+++GO:0050830///defense response to Gram-positive bacterium 19219 19219 'Ptger4' mRNA 78 59 51 1.29 0.97 0.9 3.88 3.79 4.13 1.053333333 3.933333333 271 257 278 62.66666667 268.6666667 1.85E-23 2.091608751 04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels+++04924///Renin secretion+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043025///neuronal cell body+++GO:0044306///neuron projection terminus GO:0004930///G protein-coupled receptor activity+++GO:0004955///prostaglandin receptor activity+++GO:0004957///prostaglandin E receptor activity "GO:0001818///negative regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002792///negative regulation of peptide secretion+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007254///JNK cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0010628///positive regulation of gene expression+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0010840///regulation of circadian sleep/wake cycle, wakefulness+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030278///regulation of ossification+++GO:0032496///response to lipopolysaccharide+++GO:0032690///negative regulation of interleukin-1 alpha production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033624///negative regulation of integrin activation+++GO:0035810///positive regulation of urine volume+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042093///T-helper cell differentiation+++GO:0042322///negative regulation of circadian sleep/wake cycle, REM sleep+++GO:0042466///chemokinesis+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045780///positive regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0050714///positive regulation of protein secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051492///regulation of stress fiber assembly+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:0060348///bone development+++GO:0070257///positive regulation of mucus secretion+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071260///cellular response to mechanical stimulus+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0090303///positive regulation of wound healing+++GO:0097070///ductus arteriosus closure+++GO:1900127///positive regulation of hyaluronan biosynthetic process+++GO:1904336///negative regulation of ductus arteriosus closure+++GO:1904348///negative regulation of small intestine smooth muscle contraction+++GO:1904364///positive regulation of calcitonin secretion+++GO:1904367///positive regulation of chemokinesis+++GO:1904460///positive regulation of substance P secretion+++GO:1904466///positive regulation of matrix metallopeptidase secretion+++GO:1904471///negative regulation of endothelin secretion+++GO:1904496///positive regulation of substance P secretion, neurotransmission+++GO:2000386///positive regulation of ovarian follicle development+++GO:2000388///positive regulation of antral ovarian follicle growth+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000420///negative regulation of eosinophil extravasation" 192190 192190 'Pkhd1l1' mRNA 27 34 11 0.11 0.13 0.05 0.02 0.01 0.01 0.096666667 0.013333333 4 4 2 24 3.333333333 5.15E-04 -2.841302567 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032426///stereocilium tip GO:0003674///molecular_function GO:0007605///sensory perception of sound 192191 192191 'Med9' mRNA 850 856 797 15.49 15.35 15.41 14.07 13.38 13.05 15.41666667 13.5 888 825 798 834.3333333 837 0.958801825 -0.006970191 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex GO:0001223///transcription coactivator binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding+++GO:0046965///retinoid X receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0035563///positive regulation of chromatin binding+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0051726///regulation of cell cycle+++GO:2001178///positive regulation of mediator complex assembly 192192 192192 'Shkbp1' mRNA 418 450 434 9.99 10.57 10.97 13.28 13.97 13.36 10.51 13.53666667 640 657 617 434 638 2.44E-06 0.54400602 GO:0005575///cellular_component+++GO:0005764///lysosome GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0051260///protein homooligomerization 192193 192193 'Edem1' mRNA 351 409 264 3.18 3.65 2.77 7.92 7.8 9.66 3.2 8.46 926 905 1134 341.3333333 988.3333333 2.20E-29 1.529683662 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016235///aggresome+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment "GO:0004559///alpha-mannosidase activity+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0051787///misfolded protein binding" "GO:0005975///carbohydrate metabolic process+++GO:0006986///response to unfolded protein+++GO:0008152///metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0036510///trimming of terminal mannose on C branch+++GO:0045047///protein targeting to ER+++GO:0097466///ubiquitin-dependent glycoprotein ERAD pathway+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway" 192194 192194 'Btnl10' mRNA 2 2 1 0.06 0.06 0.01 0 0 0.11 0.043333333 0.036666667 0 0 3 1.666666667 1 0.815912748 -0.730844622 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 192195 192195 'Ash1l' mRNA 2298.24 2609 2246.74 13.8 14.98 14.17 11.09 9.91 11.57 14.31666667 10.85666667 2165.01 1842.62 2098.29 2384.66 2035.306667 0.003006757 -0.239831317 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0046975///histone methyltransferase activity (H3-K36 specific) GO:0001501///skeletal system development+++GO:0002674///negative regulation of acute inflammatory response+++GO:0006325///chromatin organization+++GO:0007338///single fertilization+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0030317///flagellated sperm motility+++GO:0032259///methylation+++GO:0032635///interleukin-6 production+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043409///negative regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046697///decidualization+++GO:0048733///sebaceous gland development+++GO:0050728///negative regulation of inflammatory response+++GO:0051567///histone H3-K9 methylation+++GO:0051568///histone H3-K4 methylation+++GO:0061038///uterus morphogenesis+++GO:0097676///histone H3-K36 dimethylation+++GO:1903699///tarsal gland development+++GO:1903709///uterine gland development 192196 192196 'Luc7l2' mRNA 2058.44 1957.28 1806.77 14.64 13.55 13.69 14.9 12.8 14.75 13.96 14.15 2321.03 2049.61 2232.58 1940.83 2201.073333 0.026227625 0.170440464 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005685///U1 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome GO:0003729///mRNA binding+++GO:0019899///enzyme binding GO:0006376///mRNA splice site selection 192197 192197 'Bcas3' mRNA 2819 3003 2950 41.01 43.1 45.66 20.43 19.35 21.76 43.25666667 20.51333333 1624 1499 1678 2924 1600.333333 1.00E-32 -0.882756636 GO:0000407///phagophore assembly site+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0031252///cell leading edge+++GO:0035327///transcriptionally active chromatin+++GO:0045111///intermediate filament cytoskeleton+++GO:0071944///cell periphery GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0010698///acetyltransferase activator activity+++GO:0016922///nuclear receptor binding+++GO:0035035///histone acetyltransferase binding+++GO:0035091///phosphatidylinositol binding+++GO:0035257///nuclear hormone receptor binding+++GO:0042393///histone binding+++GO:0048487///beta-tubulin binding GO:0001525///angiogenesis+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0010595///positive regulation of endothelial cell migration+++GO:0031023///microtubule organizing center organization+++GO:0034260///negative regulation of GTPase activity+++GO:0035148///tube formation+++GO:0042594///response to starvation+++GO:0043085///positive regulation of catalytic activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051491///positive regulation of filopodium assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0071391///cellular response to estrogen stimulus+++GO:0090316///positive regulation of intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:2000251///positive regulation of actin cytoskeleton reorganization 192198 192198 'Lrrc4' mRNA 233 231 201 3.49 3.41 3.19 1.65 1.49 1.64 3.363333333 1.593333333 127 112 122 221.6666667 120.3333333 2.58E-06 -0.891534948 04360///Axon guidance+++04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043197///dendritic spine+++GO:0044309///neuron spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0099560///synaptic membrane adhesion+++GO:1904861///excitatory synapse assembly 192199 192199 'Rspo1' mRNA 74 90 52 2.32 2.78 1.73 0.57 0.74 0.65 2.276666667 0.653333333 21 26 23 72 23.33333333 2.24E-05 -1.626674838 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002090///regulation of receptor internalization+++GO:0007140///male meiotic nuclear division+++GO:0010468///regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0050896///response to stimulus+++GO:0060070///canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:2000254///regulation of male germ cell proliferation 19220 19220 'Ptgfr' mRNA 64 66 52 0.78 0.79 0.67 1.06 0.95 1.22 0.746666667 1.076666667 100 88 112 60.66666667 100 0.013791218 0.712463707 04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004955///prostaglandin receptor activity+++GO:0004958///prostaglandin F receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0043066///negative regulation of apoptotic process+++GO:0071799///cellular response to prostaglandin D stimulus 192200 192200 'Wfdc12' mRNA 6 5 10 0.58 0.48 1.03 2.3 3.67 3.08 0.696666667 3.016666667 27 42 35 7 34.66666667 1.69E-04 2.291045597 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0042742///defense response to bacterium+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 192201 192201 'Wfdc15b' mRNA 1 0 5 0.18 0 0.79 0 0 0 0.323333333 0 0 0 0 2 0 0.283462188 -3.510712356 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0042742///defense response to bacterium+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 19221 19221 'Ptgfrn' mRNA 287.95 235.88 225.13 1.97 1.51 1.39 1.33 1.28 1.59 1.623333333 1.4 207.44 204.82 247.46 249.6533333 219.9066667 0.350600508 -0.1925287 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045171///intercellular bridge GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0016567///protein ubiquitination+++GO:0034389///lipid droplet organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060348///bone development" 192212 192212 'Prom2' mRNA 4488 4929 4633 56.64 61.17 62 35.68 35.01 34.31 59.93666667 35 3256 3120 3032 4683.333333 3136 8.18E-21 -0.590952056 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031528///microvillus membrane+++GO:0042995///cell projection+++GO:0044393///microspike+++GO:0045121///membrane raft+++GO:0060170///ciliary membrane+++GO:0071914///prominosome GO:0015485///cholesterol binding GO:0001934///positive regulation of protein phosphorylation+++GO:0031346///positive regulation of cell projection organization+++GO:0043087///regulation of GTPase activity+++GO:0048550///negative regulation of pinocytosis+++GO:2001287///negative regulation of caveolin-mediated endocytosis 192216 192216 'Tmem47' mRNA 2545 2743 2833 33.62 35.64 39.7 31.72 28.38 31.08 36.32 30.39333333 2764 2416 2623 2707 2601 0.457339791 -0.072870868 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005515///protein binding GO:0098609///cell-cell adhesion 19222 19222 'Ptgir' mRNA 9 15 10 0.18 0.24 0.17 0.96 1.28 1.04 0.196666667 1.093333333 59 88 70 11.33333333 72.33333333 1.29E-09 2.669120558 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction+++04611///Platelet activation GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016501///prostacyclin receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0048662///negative regulation of smooth muscle cell proliferation 19223 19223 'Ptgis' mRNA 317 274 287 10.44 9 10.11 4.46 3.97 4.72 9.85 4.383333333 160 141 166 292.6666667 155.6666667 8.09E-08 -0.923662552 00590///Arachidonic acid metabolism GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008116///prostaglandin-I synthase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0001516///prostaglandin biosynthetic process+++GO:0001666///response to hypoxia+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006690///icosanoid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0007566///embryo implantation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0046697///decidualization+++GO:0050728///negative regulation of inflammatory response+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071456///cellular response to hypoxia+++GO:0097190///apoptotic signaling pathway+++GO:1900119///positive regulation of execution phase of apoptosis 192231 192231 'Hexim1' mRNA 370 322 341 5.93 5.07 5.79 6.21 5.77 6.51 5.596666667 6.163333333 446 405 453 344.3333333 434.6666667 0.02291965 0.323159072 GO:0000214///tRNA-intron endonuclease complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005849///mRNA cleavage factor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017069///snRNA binding+++GO:0042802///identical protein binding+++GO:0046404///ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity+++GO:0051731///polynucleotide 5'-hydroxyl-kinase activity+++GO:0051733///polydeoxyribonucleotide kinase activity+++GO:0051734///ATP-dependent polynucleotide kinase activity+++GO:0051736///ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity+++GO:0097322///7SK snRNA binding+++GO:0106140///P-TEFb complex binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006378///mRNA polyadenylation+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0007507///heart development+++GO:0008033///tRNA processing+++GO:0016310///phosphorylation+++GO:0021695///cerebellar cortex development+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031124///mRNA 3'-end processing+++GO:0032897///negative regulation of viral transcription+++GO:0035087///siRNA loading onto RISC involved in RNA interference+++GO:0045087///innate immune response+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901798///positive regulation of signal transduction by p53 class mediator" 192232 192232 'Hps4' mRNA 815 881 798 13.04 14.06 13.71 8.81 7.19 8.38 13.60333333 8.126666667 624 508 583 831.3333333 571.6666667 2.28E-07 -0.55259858 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0031085///BLOC-3 complex+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0042827///platelet dense granule GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0046983///protein dimerization activity GO:0006605///protein targeting+++GO:0006996///organelle organization+++GO:0007040///lysosome organization+++GO:0007596///blood coagulation+++GO:0016192///vesicle-mediated transport+++GO:0030318///melanocyte differentiation+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:1903232///melanosome assembly 192236 192236 'Hps1' mRNA 490.46 505.73 420.18 8 8.58 7.46 9.5 9.33 8.94 8.013333333 9.256666667 611.73 587.8 558.91 472.1233333 586.1466667 0.011552388 0.30228549 GO:0031085///BLOC-3 complex+++GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046983///protein dimerization activity GO:0000902///cell morphogenesis+++GO:0003016///respiratory system process+++GO:0006882///cellular zinc ion homeostasis+++GO:0006954///inflammatory response+++GO:0006996///organelle organization+++GO:0007040///lysosome organization+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007596///blood coagulation+++GO:0009306///protein secretion+++GO:0010467///gene expression+++GO:0016192///vesicle-mediated transport+++GO:0030318///melanocyte differentiation+++GO:0030324///lung development+++GO:0032816///positive regulation of natural killer cell activation+++GO:0033299///secretion of lysosomal enzymes+++GO:0043473///pigmentation+++GO:0048069///eye pigmentation+++GO:0050790///regulation of catalytic activity+++GO:0055088///lipid homeostasis+++GO:0060041///retina development in camera-type eye+++GO:0060425///lung morphogenesis+++GO:1903232///melanosome assembly 19224 19224 'Ptgs1' mRNA 251 253 284 4.81 4.77 5.7 11.14 10.78 11.01 5.093333333 10.97666667 672 636 640 262.6666667 649.3333333 3.57E-24 1.290899166 00590///Arachidonic acid metabolism+++04611///Platelet activation+++04726///Serotonergic synapse+++04923///Regulation of lipolysis in adipocytes GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045277///respiratory chain complex IV+++GO:0070469///respiratory chain "GO:0004129///cytochrome-c oxidase activity+++GO:0004601///peroxidase activity+++GO:0004666///prostaglandin-endoperoxide synthase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001516///prostaglandin biosynthetic process+++GO:0006119///oxidative phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0006954///inflammatory response+++GO:0006979///response to oxidative stress+++GO:0007612///learning+++GO:0007613///memory+++GO:0008217///regulation of blood pressure+++GO:0009060///aerobic respiration+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0019233///sensory perception of pain+++GO:0019371///cyclooxygenase pathway+++GO:0022900///electron transport chain+++GO:0030216///keratinocyte differentiation+++GO:0032811///negative regulation of epinephrine secretion+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042127///regulation of cell proliferation+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0098869///cellular oxidant detoxification+++GO:1902600///proton transmembrane transport 19225 19225 'Ptgs2' mRNA 94 96 86 1.13 1.14 1.1 0.91 1.03 1.14 1.123333333 1.026666667 87 96 106 92 96.33333333 0.863090843 0.05724027 00590///Arachidonic acid metabolism+++04064///NF-kappa B signaling pathway+++04370///VEGF signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05140///Leishmaniasis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05206///MicroRNAs in cancer+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070469///respiratory chain "GO:0004129///cytochrome-c oxidase activity+++GO:0004601///peroxidase activity+++GO:0004666///prostaglandin-endoperoxide synthase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" "GO:0001516///prostaglandin biosynthetic process+++GO:0001525///angiogenesis+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0006954///inflammatory response+++GO:0006979///response to oxidative stress+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0007612///learning+++GO:0007613///memory+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009314///response to radiation+++GO:0009750///response to fructose+++GO:0010033///response to organic substance+++GO:0010042///response to manganese ion+++GO:0010226///response to lithium ion+++GO:0010243///response to organonitrogen compound+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0019233///sensory perception of pain+++GO:0019371///cyclooxygenase pathway+++GO:0022900///electron transport chain+++GO:0030216///keratinocyte differentiation+++GO:0030282///bone mineralization+++GO:0030728///ovulation+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0031622///positive regulation of fever generation+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032227///negative regulation of synaptic transmission, dopaminergic+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033280///response to vitamin D+++GO:0034097///response to cytokine+++GO:0034605///cellular response to heat+++GO:0034612///response to tumor necrosis factor+++GO:0034644///cellular response to UV+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0042127///regulation of cell proliferation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0042633///hair cycle+++GO:0042640///anagen+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045786///negative regulation of cell cycle+++GO:0045907///positive regulation of vasoconstriction+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046697///decidualization+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050873///brown fat cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0051926///negative regulation of calcium ion transport+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070542///response to fatty acid+++GO:0071260///cellular response to mechanical stimulus+++GO:0071284///cellular response to lead ion+++GO:0071318///cellular response to ATP+++GO:0071456///cellular response to hypoxia+++GO:0071471///cellular response to non-ionic osmotic stress+++GO:0071498///cellular response to fluid shear stress+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0090362///positive regulation of platelet-derived growth factor production+++GO:0098869///cellular oxidant detoxification+++GO:0150077///regulation of neuroinflammatory response+++GO:1902219///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:1902600///proton transmembrane transport+++GO:1990776///response to angiotensin" 19226 19226 'Pth' mRNA 5 5 1 0.49 0.49 0.11 0.35 0.53 0.36 0.363333333 0.413333333 4 6 4 3.666666667 4.666666667 0.8347718 0.359898815 "04080///Neuroactive ligand-receptor interaction+++04928///Parathyroid hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++05323///Rheumatoid arthritis" GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0031856///parathyroid hormone receptor binding+++GO:0031857///type 1 parathyroid hormone receptor binding+++GO:0047485///protein N-terminus binding+++GO:0048018///receptor ligand activity+++GO:0051428///peptide hormone receptor binding GO:0006874///cellular calcium ion homeostasis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0007266///Rho protein signal transduction+++GO:0007267///cell-cell signaling+++GO:0009967///positive regulation of signal transduction+++GO:0010288///response to lead ion+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010960///magnesium ion homeostasis+++GO:0030282///bone mineralization+++GO:0030501///positive regulation of bone mineralization+++GO:0031667///response to nutrient levels+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0033280///response to vitamin D+++GO:0034645///cellular macromolecule biosynthetic process+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045778///positive regulation of ossification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0046686///response to cadmium ion+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0055062///phosphate ion homeostasis+++GO:0055074///calcium ion homeostasis+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0071107///response to parathyroid hormone+++GO:0071774///response to fibroblast growth factor+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0071866///negative regulation of apoptotic process in bone marrow+++GO:0090290///positive regulation of osteoclast proliferation+++GO:1900158///negative regulation of bone mineralization involved in bone maturation 19227 19227 'Pthlh' mRNA 19 29 27 0.78 1.18 1.18 1.19 1.8 0.97 1.046666667 1.32 33 49 26 25 36 0.346505618 0.515380833 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0005179///hormone activity+++GO:0051428///peptide hormone receptor binding GO:0001501///skeletal system development+++GO:0001958///endochondral ossification+++GO:0002076///osteoblast development+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007492///endoderm development+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010960///magnesium ion homeostasis+++GO:0016485///protein processing+++GO:0030282///bone mineralization+++GO:0030855///epithelial cell differentiation+++GO:0032330///regulation of chondrocyte differentiation+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0043129///surfactant homeostasis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0048286///lung alveolus development+++GO:0055062///phosphate ion homeostasis+++GO:0055074///calcium ion homeostasis+++GO:0060649///mammary gland bud elongation+++GO:0060659///nipple sheath formation+++GO:0061182///negative regulation of chondrocyte development 19228 19228 'Pth1r' mRNA 58 80 77 1.53 2.06 2.19 1.4 1.94 1.13 1.926666667 1.49 61 82 47 71.66666667 63.33333333 0.658259037 -0.190313881 "04080///Neuroactive ligand-receptor interaction+++04928///Parathyroid hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption" GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004991///parathyroid hormone receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association "GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001701///in utero embryonic development+++GO:0002062///chondrocyte differentiation+++GO:0002076///osteoblast development+++GO:0006874///cellular calcium ion homeostasis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0030282///bone mineralization+++GO:0045453///bone resorption+++GO:0048469///cell maturation+++GO:0060732///positive regulation of inositol phosphate biosynthetic process" 192285 192285 'Phf21a' mRNA 1030.01 1085.29 873.88 11.1 11.09 9.47 7.41 7.16 7.08 10.55333333 7.216666667 793 752.99 740.06 996.3933333 762.0166667 4.33E-05 -0.395533025 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:1990391///DNA repair complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001967///suckling behavior+++GO:0006325///chromatin organization 192287 192287 'Slc25a36' mRNA 3088 3066 3024 35.48 34.93 36.8 24.24 23 25.03 35.73666667 24.09 2482 2282 2437 3059.333333 2400.333333 4.02E-08 -0.362751939 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015218///pyrimidine nucleotide transmembrane transporter activity GO:0000002///mitochondrial genome maintenance+++GO:0006864///pyrimidine nucleotide transport+++GO:0007005///mitochondrion organization+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0055085///transmembrane transport+++GO:1990519///pyrimidine nucleotide import into mitochondrion 192289 192289 'Tmlhe' mRNA 28.99 25 28 0.72 0.61 0.73 1.38 0.68 1.29 0.686666667 1.116666667 63.94 31 58.09 27.33 51.01 0.048095436 0.889827007 00310///Lysine degradation GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0050353///trimethyllysine dioxygenase activity+++GO:0051213///dioxygenase activity" GO:0045329///carnitine biosynthetic process+++GO:0051354///negative regulation of oxidoreductase activity 19229 19229 'Ptk2b' mRNA 566 630 677 7.68 8.42 9.73 20.29 17.25 20.22 8.61 19.25333333 1706 1422 1640 624.3333333 1589.333333 3.29E-37 1.331745298 04020///Calcium signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04670///Leukocyte transendothelial migration+++04912///GnRH signaling pathway+++05135///Yersinia infection+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043423///3-phosphoinositide-dependent protein kinase binding+++GO:0044877///protein-containing complex binding "GO:0000165///MAPK cascade+++GO:0000302///response to reactive oxygen species+++GO:0001525///angiogenesis+++GO:0001556///oocyte maturation+++GO:0001666///response to hypoxia+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002040///sprouting angiogenesis+++GO:0002250///adaptive immune response+++GO:0002315///marginal zone B cell differentiation+++GO:0002376///immune system process+++GO:0002688///regulation of leukocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006968///cellular defense response+++GO:0006970///response to osmotic stress+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007172///signal complex assembly+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007229///integrin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009612///response to mechanical stimulus+++GO:0009725///response to hormone+++GO:0009749///response to glucose+++GO:0010226///response to lithium ion+++GO:0010243///response to organonitrogen compound+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0010752///regulation of cGMP-mediated signaling+++GO:0010758///regulation of macrophage chemotaxis+++GO:0010976///positive regulation of neuron projection development+++GO:0014009///glial cell proliferation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030279///negative regulation of ossification+++GO:0030307///positive regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030500///regulation of bone mineralization+++GO:0030502///negative regulation of bone mineralization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031175///neuron projection development+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032960///regulation of inositol trisphosphate biosynthetic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0035902///response to immobilization stress+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042976///activation of Janus kinase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0043149///stress fiber assembly+++GO:0043267///negative regulation of potassium ion transport+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043534///blood vessel endothelial cell migration+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045087///innate immune response+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045453///bone resorption+++GO:0045471///response to ethanol+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045727///positive regulation of translation+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048041///focal adhesion assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071300///cellular response to retinoic acid+++GO:0071498///cellular response to fluid shear stress+++GO:0086100///endothelin receptor signaling pathway+++GO:0090630///activation of GTPase activity+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000114///regulation of establishment of cell polarity+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000310///regulation of NMDA receptor activity+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000538///positive regulation of B cell chemotaxis+++GO:2000573///positive regulation of DNA biosynthetic process" 192292 192292 'Nrbp1' mRNA 2208 2374 2273 57.72 61.16 63.16 70.29 69.87 70.86 60.68 70.34 3075 2983 3000 2285 3019.333333 5.84E-09 0.389745126 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006468///protein phosphorylation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007254///JNK cascade+++GO:0035556///intracellular signal transduction 19230 19230 'Twf1' mRNA 12351 12238 12609 226.8 220.84 246.32 124.82 120.96 124.44 231.32 123.4066667 7784 7401 7543 12399.33333 7576 1.96E-36 -0.724589937 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril+++GO:0030175///filopodium+++GO:0032587///ruffle membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding" GO:0010591///regulation of lamellipodium assembly+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010976///positive regulation of neuron projection development+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030042///actin filament depolymerization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0042989///sequestering of actin monomers+++GO:0043538///regulation of actin phosphorylation+++GO:0051016///barbed-end actin filament capping 19231 19231 'Ptma' mRNA 9535.73 9727 9232.3 412.03 414.72 423.22 540.89 497.1 552.03 416.6566667 530.0066667 14375 12888.75 14191 9498.343333 13818.25 2.65E-23 0.528466495 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0042393///histone binding GO:0043066///negative regulation of apoptotic process+++GO:0043486///histone exchange+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 19240 19240 'Tmsb10' mRNA 866 824 889 120.25 113.98 131.32 680.3 838.87 725.88 121.85 748.35 5573 6676 5727 859.6666667 5992 1.80E-219 2.789328804 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0003785///actin monomer binding GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0042989///sequestering of actin monomers 19241 19241 'Tmsb4x' mRNA 9473 9591 9152 1024.75 1032.14 1052.27 4308.45 4696.62 4363.56 1036.386667 4456.21 45352 48086 44315 9405.333333 45917.66667 0 2.276486301 04810///Regulation of actin cytoskeleton GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding "GO:0007015///actin filament organization+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030334///regulation of cell migration+++GO:0032717///negative regulation of interleukin-8 production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042989///sequestering of actin monomers+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050727///regulation of inflammatory response+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1905273///positive regulation of proton-transporting ATP synthase activity, rotational mechanism+++GO:2001028///positive regulation of endothelial cell chemotaxis+++GO:2001171///positive regulation of ATP biosynthetic process" 19242 19242 'Ptn' mRNA 17892 18442 17212 668.31 679.52 681.9 638.43 618.68 640 676.5766667 632.37 19655 18578 19052 17848.66667 19095 0.090154938 0.08571284 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0004864///protein phosphatase inhibitor activity+++GO:0005178///integrin binding+++GO:0005539///glycosaminoglycan binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0019901///protein kinase binding+++GO:0035373///chondroitin sulfate proteoglycan binding+++GO:0035374///chondroitin sulfate binding+++GO:0038085///vascular endothelial growth factor binding+++GO:0043394///proteoglycan binding+++GO:0045545///syndecan binding+++GO:1904399///heparan sulfate binding GO:0001503///ossification+++GO:0001889///liver development+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0007165///signal transduction+++GO:0007229///integrin-mediated signaling pathway+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007612///learning+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010594///regulation of endothelial cell migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0010996///response to auditory stimulus+++GO:0014823///response to activity+++GO:0016525///negative regulation of angiogenesis+++GO:0021510///spinal cord development+++GO:0021549///cerebellum development+++GO:0021794///thalamus development+++GO:0030282///bone mineralization+++GO:0030324///lung development+++GO:0030336///negative regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030902///hindbrain development+++GO:0031104///dendrite regeneration+++GO:0031641///regulation of myelination+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0034644///cellular response to UV+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042246///tissue regeneration+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043113///receptor clustering+++GO:0043932///ossification involved in bone remodeling+++GO:0044849///estrous cycle+++GO:0045446///endothelial cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045778///positive regulation of ossification+++GO:0045837///negative regulation of membrane potential+++GO:0046697///decidualization+++GO:0048167///regulation of synaptic plasticity+++GO:0048477///oogenesis+++GO:0048680///positive regulation of axon regeneration+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051781///positive regulation of cell division+++GO:0060041///retina development in camera-type eye+++GO:0060221///retinal rod cell differentiation+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060291///long-term synaptic potentiation+++GO:0071305///cellular response to vitamin D+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0072201///negative regulation of mesenchymal cell proliferation+++GO:0140059///dendrite arborization+++GO:1900006///positive regulation of dendrite development+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1903706///regulation of hemopoiesis+++GO:1904373///response to kainic acid+++GO:1904389///rod bipolar cell differentiation+++GO:1904391///response to ciliary neurotrophic factor+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:1904397///negative regulation of neuromuscular junction development+++GO:1990089///response to nerve growth factor+++GO:2000036///regulation of stem cell population maintenance+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000738///positive regulation of stem cell differentiation 19243 19243 'Ptp4a1' mRNA 3837 4082 3945 50.06 52.38 54.57 54.31 53.71 52.88 52.33666667 53.63333333 4792 4631 4521 3954.666667 4648 5.23E-04 0.220431431 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004727///prenylated protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016311///dephosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0035335///peptidyl-tyrosine dephosphorylation 19244 19244 'Ptp4a2' mRNA 8299 7942 9135 130.6 123 153.13 170.75 158.25 164.6 135.5766667 164.5333333 12466 11236 11637 8458.666667 11779.66667 1.62E-09 0.460756041 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 19245 19245 'Ptp4a3' mRNA 554 522 522.14 18.34 17.3 18.28 20.54 18.86 18.35 17.97333333 19.25 710 628 602.06 532.7133333 646.6866667 0.025517584 0.26673704 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006470///protein dephosphorylation+++GO:0007219///Notch signaling pathway+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043117///positive regulation of vascular permeability+++GO:0043542///endothelial cell migration+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904951///positive regulation of establishment of protein localization+++GO:1990830///cellular response to leukemia inhibitory factor" 19246 19246 'Ptpn1' mRNA 1026 1076 1050 12.85 13.24 14.05 35.58 34.03 36.09 13.38 35.23333333 3228 3021 3177 1050.666667 3142 4.47E-111 1.567816333 04520///Adherens junction+++04910///Insulin signaling pathway+++04931///Insulin resistance+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0097443///sorting endosome+++GO:0098554///cytoplasmic side of endoplasmic reticulum membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005158///insulin receptor binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046875///ephrin receptor binding+++GO:0051721///protein phosphatase 2A binding GO:0006470///protein dephosphorylation+++GO:0007257///activation of JUN kinase activity+++GO:0008286///insulin receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0016311///dephosphorylation+++GO:0030100///regulation of endocytosis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031532///actin cytoskeleton reorganization+++GO:0033157///regulation of intracellular protein transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902202///regulation of hepatocyte growth factor receptor signaling pathway+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903898///negative regulation of PERK-mediated unfolded protein response+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity+++GO:2000646///positive regulation of receptor catabolic process 19247 19247 'Ptpn11' mRNA 1440 1352 995 13.67 12.62 10.01 11.29 10.48 11.12 12.1 10.96333333 1369 1242 1307 1262.333333 1306 0.763426269 0.043210982 04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04360///Axon guidance+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04920///Adipocytokine signaling pathway+++04931///Insulin resistance+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma+++05220///Chronic myeloid leukemia+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043229///intracellular organelle+++GO:0044306///neuron projection terminus+++GO:0044309///neuron spine+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098685///Schaffer collateral - CA1 synapse GO:0000149///SNARE binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017075///syntaxin-1 binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0031748///D1 dopamine receptor binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0043560///insulin receptor substrate binding+++GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0050839///cell adhesion molecule binding+++GO:0051428///peptide hormone receptor binding+++GO:1990782///protein tyrosine kinase binding GO:0000077///DNA damage checkpoint+++GO:0000187///activation of MAPK activity+++GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006897///endocytosis+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0009967///positive regulation of signal transduction+++GO:0016311///dephosphorylation+++GO:0021697///cerebellar cortex formation+++GO:0030220///platelet formation+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032528///microvillus organization+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033277///abortive mitotic cell cycle+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0035264///multicellular organism growth+++GO:0035265///organ growth+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035855///megakaryocyte development+++GO:0036302///atrioventricular canal development+++GO:0038127///ERBB signaling pathway+++GO:0042445///hormone metabolic process+++GO:0042593///glucose homeostasis+++GO:0043254///regulation of protein complex assembly+++GO:0043408///regulation of MAPK cascade+++GO:0045778///positive regulation of ossification+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046326///positive regulation of glucose import+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046676///negative regulation of insulin secretion+++GO:0046825///regulation of protein export from nucleus+++GO:0046887///positive regulation of hormone secretion+++GO:0046888///negative regulation of hormone secretion+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048013///ephrin receptor signaling pathway+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048488///synaptic vesicle endocytosis+++GO:0048609///multicellular organismal reproductive process+++GO:0048659///smooth muscle cell proliferation+++GO:0048806///genitalia development+++GO:0048839///inner ear development+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051463///negative regulation of cortisol secretion+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060020///Bergmann glial cell differentiation+++GO:0060125///negative regulation of growth hormone secretion+++GO:0060325///face morphogenesis+++GO:0061582///intestinal epithelial cell migration+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071260///cellular response to mechanical stimulus+++GO:0071310///cellular response to organic substance+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1904385///cellular response to angiotensin+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000474///regulation of opioid receptor signaling pathway 19248 19248 'Ptpn12' mRNA 162.06 213.36 175.41 2.06 2.78 2.41 5.45 5.23 5.76 2.416666667 5.48 452.21 408.5 464.43 183.61 441.7133333 1.49E-16 1.256650636 GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0042246///tissue regeneration+++GO:0071364///cellular response to epidermal growth factor stimulus 19249 19249 'Ptpn13' mRNA 2770 2734 2288 17.58 17.06 15.4 11.16 11.31 12.66 16.68 11.71 2025 2005 2225 2597.333333 2085 3.19E-05 -0.325003371 04210///Apoptosis GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044297///cell body GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0016311///dephosphorylation+++GO:0031047///gene silencing by RNA+++GO:0035335///peptidyl-tyrosine dephosphorylation 19250 19250 'Ptpn14' mRNA 661 672 608 3.22 3.22 3.14 3.25 2.73 3.39 3.193333333 3.123333333 767 631 778 647 725.3333333 0.220232931 0.153247321 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003712///transcription coregulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030971///receptor tyrosine kinase binding "GO:0001946///lymphangiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006470///protein dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046825///regulation of protein export from nucleus" 19252 19252 'Dusp1' mRNA 904 961 892 26.59 27.85 27.83 34.98 36.83 32.31 27.42333333 34.70666667 1367 1405 1222 919 1331.333333 8.13E-09 0.523570902 04010///MAPK signaling pathway+++04726///Serotonergic synapse+++05012///Parkinson disease+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0019838///growth factor binding+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0001706///endoderm formation+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007162///negative regulation of cell adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0009416///response to light stimulus+++GO:0010033///response to organic substance+++GO:0016311///dephosphorylation+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032870///cellular response to hormone stimulus+++GO:0033574///response to testosterone+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0051384///response to glucocorticoid+++GO:0051447///negative regulation of meiotic cell cycle+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0051726///regulation of cell cycle+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071850///mitotic cell cycle arrest+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1903753///negative regulation of p38MAPK cascade+++GO:1990869///cellular response to chemokine+++GO:2000279///negative regulation of DNA biosynthetic process 19253 19253 'Ptpn18' mRNA 236 248 254 8.87 9.2 10.2 25.78 28.1 26.52 9.423333333 26.8 743 794 744 246 760.3333333 2.37E-40 1.615804714 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0001825///blastocyst formation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 19255 19255 'Ptpn2' mRNA 630 652 656 18.06 18.33 19.72 32.48 29.91 30.97 18.70333333 31.12 1171 1042 1079 646 1097.333333 3.02E-15 0.750741668 04630///JAK-STAT signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0019905///syntaxin binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0097677///STAT family protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006470///protein dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010888///negative regulation of lipid storage+++GO:0016311///dephosphorylation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042593///glucose homeostasis+++GO:0045650///negative regulation of macrophage differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050728///negative regulation of inflammatory response+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050922///negative regulation of chemotaxis+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0070104///negative regulation of interleukin-6-mediated signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902202///regulation of hepatocyte growth factor receptor signaling pathway+++GO:1902206///negative regulation of interleukin-2-mediated signaling pathway+++GO:1902215///negative regulation of interleukin-4-mediated signaling pathway+++GO:1902227///negative regulation of macrophage colony-stimulating factor signaling pathway+++GO:1902233///negative regulation of positive thymic T cell selection+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903899///positive regulation of PERK-mediated unfolded protein response+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway 19258 19258 'Ptpn4' mRNA 813 835 488 6.33 6.07 3.1 2.48 3.27 3.34 5.166666667 3.03 442 498 507 712 482.3333333 4.91E-04 -0.56128154 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0035254///glutamate receptor binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 19259 19259 'Ptpn5' mRNA 54 46 40 0.94 0.79 0.77 0.44 0.42 0.47 0.833333333 0.443333333 28 26 29 46.66666667 27.66666667 0.075323777 -0.762878063 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0097060///synaptic membrane+++GO:1990635///proximal dendrite GO:0001784///phosphotyrosine residue binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0035254///glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0051019///mitogen-activated protein kinase binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002092///positive regulation of receptor internalization+++GO:0006470///protein dephosphorylation+++GO:0010976///positive regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035640///exploration behavior+++GO:0035902///response to immobilization stress+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043407///negative regulation of MAP kinase activity+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1901216///positive regulation of neuron death+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:2001025///positive regulation of response to drug 19260 19260 'Ptpn22' mRNA 571 564 662 11.2 10.77 13.84 4.04 3.69 4.62 11.93666667 4.116666667 235 210 257 599 234 2.53E-21 -1.372875985 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:1990782///protein tyrosine kinase binding "GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002577///regulation of antigen processing and presentation+++GO:0002685///regulation of leukocyte migration+++GO:0006470///protein dephosphorylation+++GO:0006914///autophagy+++GO:0010507///negative regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016311///dephosphorylation+++GO:0030217///T cell differentiation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032481///positive regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032817///regulation of natural killer cell proliferation+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035644///phosphoanandamide dephosphorylation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043508///negative regulation of JUN kinase activity+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050852///T cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070433///negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071225///cellular response to muramyl dipeptide+++GO:0071663///positive regulation of granzyme B production+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1902523///positive regulation of protein K63-linked ubiquitination+++GO:1903169///regulation of calcium ion transmembrane transport+++GO:1903753///negative regulation of p38MAPK cascade+++GO:2000566///positive regulation of CD8-positive, alpha-beta T cell proliferation" 19261 19261 'Sirpa' mRNA 1516 1510 1141 22.7 22.37 18.25 64.75 70.37 71.74 21.10666667 68.95333333 4987 5354 5393.98 1389 5244.993333 7.19E-122 1.911465355 04380///Osteoclast differentiation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019903///protein phosphatase binding+++GO:0030695///GTPase regulator activity+++GO:0045309///protein phosphorylated amino acid binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion+++GO:0098632///cell-cell adhesion mediator activity+++GO:1990405///protein antigen binding+++GO:1990782///protein tyrosine kinase binding "GO:0001933///negative regulation of protein phosphorylation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0006928///movement of cell or subcellular component+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007160///cell-matrix adhesion+++GO:0010468///regulation of gene expression+++GO:0016477///cell migration+++GO:0032649///regulation of interferon-gamma production+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032688///negative regulation of interferon-beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035696///monocyte extravasation+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0046329///negative regulation of JNK cascade+++GO:0050728///negative regulation of inflammatory response+++GO:0050765///negative regulation of phagocytosis+++GO:0050766///positive regulation of phagocytosis+++GO:0050790///regulation of catalytic activity+++GO:0050870///positive regulation of T cell activation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071349///cellular response to interleukin-12+++GO:0071641///negative regulation of macrophage inflammatory protein 1 alpha production+++GO:0071650///negative regulation of chemokine (C-C motif) ligand 5 production+++GO:0097530///granulocyte migration+++GO:0098609///cell-cell adhesion+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1903720///negative regulation of I-kappaB phosphorylation" 19262 19262 'Ptpra' mRNA 1024 978 871 16.18 15.22 14.71 15.13 12.36 16.26 15.37 14.58333333 1095 870 1134 957.6666667 1033 0.448150055 0.098248567 GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034704///calcium channel complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099699///integral component of synaptic membrane GO:0000166///nucleotide binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008160///protein tyrosine phosphatase activator activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0019211///phosphatase activator activity+++GO:0019888///protein phosphatase regulator activity+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051721///protein phosphatase 2A binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0007052///mitotic spindle organization+++GO:0007229///integrin-mediated signaling pathway+++GO:0008286///insulin receptor signaling pathway+++GO:0016311///dephosphorylation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050790///regulation of catalytic activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051893///regulation of focal adhesion assembly 19263 19263 'Ptprb' mRNA 402 369 434 2.01 1.78 2.29 2.2 1.78 1.94 2.026666667 1.973333333 528 395 443 401.6666667 455.3333333 0.341434203 0.163023406 04520///Adherens junction GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030246///carbohydrate binding+++GO:0045296///cadherin binding GO:0001525///angiogenesis+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 19264 19264 'Ptprc' mRNA 145 161 167 1.51 1.72 1.83 17.59 15.92 16.43 1.686666667 16.64666667 1918 1693 1738 157.6666667 1783 5.20E-223 3.485779806 04514///Cell adhesion molecules+++04660///T cell receptor signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++05340///Primary immunodeficiency GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0009897///external side of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032059///bleb+++GO:0045121///membrane raft+++GO:0071944///cell periphery+++GO:0098857///membrane microdomain GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0030506///ankyrin binding+++GO:0030507///spectrin binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0000187///activation of MAPK activity+++GO:0001779///natural killer cell differentiation+++GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002711///positive regulation of T cell mediated immunity+++GO:0002923///regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006469///negative regulation of protein kinase activity+++GO:0006470///protein dephosphorylation+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0007159///leukocyte cell-cell adhesion+++GO:0010332///response to gamma radiation+++GO:0010468///regulation of gene expression+++GO:0016311///dephosphorylation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031668///cellular response to extracellular stimulus+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032677///regulation of interleukin-8 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0042098///T cell proliferation+++GO:0042100///B cell proliferation+++GO:0042102///positive regulation of T cell proliferation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0044770///cell cycle phase transition+++GO:0044855///plasma membrane raft distribution+++GO:0045059///positive thymic T cell selection+++GO:0045060///negative thymic T cell selection+++GO:0045582///positive regulation of T cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0048539///bone marrow development+++GO:0048864///stem cell development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050764///regulation of phagocytosis+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0050857///positive regulation of antigen receptor-mediated signaling pathway+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0061097///regulation of protein tyrosine kinase activity+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1903615///positive regulation of protein tyrosine phosphatase activity+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:2000473///positive regulation of hematopoietic stem cell migration+++GO:2000648///positive regulation of stem cell proliferation+++GO:2001236///regulation of extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 19265 19265 'Ptprcap' mRNA 7 10 10 0.55 0.78 0.84 2.83 1.49 1.07 0.723333333 1.796666667 41 21 15 9 25.66666667 0.028810938 1.489896273 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 192650 192650 'Cabp7' mRNA 189.61 248.71 190.59 3.44 4.44 3.66 0.5 0.42 0.58 3.846666667 0.5 31.48 25.92 35.73 209.6366667 31.04333333 1.18E-26 -2.793727394 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032588///trans-Golgi network membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 192651 192651 'Zfp286' mRNA 309.95 286.87 279.81 10.71 9.2 9.97 5.87 3.54 4.34 9.96 4.583333333 149.76 135.9 178.86 292.21 154.84 1.28E-07 -0.931189386 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 192652 192652 'Wdr81' mRNA 402 467 423 3.07 3.62 3.43 5.77 5.69 5.47 3.373333333 5.643333333 864 835 798 430.6666667 832.3333333 2.85E-18 0.93896732 GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007005///mitochondrion organization+++GO:0010923///negative regulation of phosphatase activity+++GO:0035973///aggrephagy+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045022///early endosome to late endosome transport+++GO:0050821///protein stabilization 192653 192653 'Ttc36' mRNA 5 6 1 0.45 0.54 0.1 0.71 0.49 0.49 0.363333333 0.563333333 9 6 6 4 7 0.538335554 0.812918956 GO:0005575///cellular_component GO:0005515///protein binding GO:0006570///tyrosine metabolic process+++GO:0007613///memory+++GO:0008542///visual learning+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0021954///central nervous system neuron development+++GO:0032091///negative regulation of protein binding+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0060271///cilium assembly+++GO:1902915///negative regulation of protein polyubiquitination 192654 192654 'Pla2g15' mRNA 828 936 835 16.41 18.33 17.76 35.29 35.86 37.4 17.5 36.18333333 2039 2017 2091 866.3333333 2049 3.81E-55 1.231188072 00564///Glycerophospholipid metabolism+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0004806///triglyceride lipase activity+++GO:0008270///zinc ion binding+++GO:0008374///O-acyltransferase activity+++GO:0008970///phospholipase A1 activity+++GO:0016411///acylglycerol O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0006672///ceramide metabolic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0046338///phosphatidylethanolamine catabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process 192656 192656 'Ripk2' mRNA 241 285 205 4.94 5.78 4.45 4.16 5.42 5.27 5.056666667 4.95 234 295 285 243.6666667 271.3333333 0.482367309 0.150586025 04621///NOD-like receptor signaling pathway+++04722///Neurotrophin signaling pathway+++05131///Shigellosis+++05132///Salmonella infection+++05152///Tuberculosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031982///vesicle+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030274///LIM domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0050700///CARD domain binding+++GO:0089720///caspase binding GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007257///activation of JUN kinase activity+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010942///positive regulation of cell death+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0033091///positive regulation of immature T cell proliferation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0042098///T cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050852///T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070427///nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0070555///response to interleukin-1+++GO:0070671///response to interleukin-12+++GO:0070673///response to interleukin-18+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071224///cellular response to peptidoglycan+++GO:0071225///cellular response to muramyl dipeptide+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:1904417///positive regulation of xenophagy 192657 192657 'Ell2' mRNA 399 418 203 5.93 6.11 3.2 3.11 2.93 3.31 5.08 3.116666667 241 222 248 340 237 0.019096896 -0.518684768 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0042795///snRNA transcription by RNA polymerase II 19266 19266 'Ptprd' mRNA 555 545 559 3.1 3.01 3.37 2.12 1.43 1.81 3.16 1.786666667 429 280 360 553 356.3333333 1.22E-05 -0.65040167 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0050839///cell adhesion molecule binding GO:0006470///protein dephosphorylation+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016311///dephosphorylation+++GO:0030182///neuron differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050776///regulation of immune response+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051965///positive regulation of synapse assembly+++GO:0097105///presynaptic membrane assembly+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099545///trans-synaptic signaling by trans-synaptic complex+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 192662 192662 'Arhgdia' mRNA 10112 9675 9760 309.69 291.95 317.17 519.97 510.7 514.23 306.27 514.9666667 19524 18724 18679 9849 18975.66667 4.55E-72 0.933247356 04722///Neurotrophin signaling pathway+++04962///Vasopressin-regulated water reabsorption GO:0001772///immunological synapse+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0045202///synapse GO:0005094///Rho GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0051879///Hsp90 protein binding GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030336///negative regulation of cell migration+++GO:0032880///regulation of protein localization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0071260///cellular response to mechanical stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071461///cellular response to redox state+++GO:0071526///semaphorin-plexin signaling pathway+++GO:2000249///regulation of actin cytoskeleton reorganization 192663 192663 'Abcg4' mRNA 132 182 134 1.93 2.6 2.1 1.1 1.78 1.88 2.21 1.586666667 86 135 142 149.3333333 121 0.29066452 -0.307536172 02010///ABC transporters GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0034041///sterol-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0120020///intermembrane cholesterol transfer activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0010875///positive regulation of cholesterol efflux+++GO:0015918///sterol transport+++GO:0032367///intracellular cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0042632///cholesterol homeostasis+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0055085///transmembrane transport+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0120009///intermembrane lipid transfer+++GO:1990830///cellular response to leukemia inhibitory factor" 19267 19267 'Ptpre' mRNA 1234 1301 678 12.15 12.61 7.11 8.41 9.13 8.89 10.62333333 8.81 940 1015 983 1071 979.3333333 0.73243154 -0.12591603 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042802///identical protein binding GO:0006470///protein dephosphorylation+++GO:0007185///transmembrane receptor protein tyrosine phosphatase signaling pathway+++GO:0016311///dephosphorylation+++GO:0033003///regulation of mast cell activation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046627///negative regulation of insulin receptor signaling pathway 192678 192678 'Rassf3' mRNA 382 411 280 5.88 6.45 4.69 5.45 4.55 5.44 5.673333333 5.146666667 403 320 384 357.6666667 369 0.863090843 0.03842976 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0042981///regulation of apoptotic process 19268 19268 'Ptprf' mRNA 4928 4988 4496 35.2 35.1 34.21 27.24 25.46 26.61 34.83666667 26.43666667 4380 3980 4122 4804 4160.666667 1.41E-04 -0.218424559 04514///Cell adhesion molecules+++04520///Adherens junction+++04910///Insulin signaling pathway+++04931///Insulin resistance GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0060076///excitatory synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0005158///insulin receptor binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0035373///chondroitin sulfate proteoglycan binding+++GO:0042301///phosphate ion binding+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010975///regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0016477///cell migration+++GO:0031102///neuron projection regeneration+++GO:0031345///negative regulation of cell projection organization+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048679///regulation of axon regeneration+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050803///regulation of synapse structure or activity+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0099175///regulation of postsynapse organization+++GO:0099560///synaptic membrane adhesion+++GO:1900121///negative regulation of receptor binding 19270 19270 'Ptprg' mRNA 658 573 547 3.84 3.29 3.3 2.52 2.28 2.51 3.476666667 2.436666667 511 452 488 592.6666667 483.6666667 0.013766519 -0.304361651 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004089///carbonate dehydratase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042802///identical protein binding GO:0006470///protein dephosphorylation+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010977///negative regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:1901998///toxin transport 19271 19271 'Ptprj' mRNA 789 866 695 5.43 5.85 5.06 9.01 7.79 8.63 5.446666667 8.476666667 1503 1276 1397 783.3333333 1392 3.34E-19 0.819688534 04520///Adherens junction+++05208///Chemical carcinogenesis - reactive oxygen species GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0008013///beta-catenin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070097///delta-catenin binding GO:0001570///vasculogenesis+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006470///protein dephosphorylation+++GO:0007507///heart development+++GO:0007596///blood coagulation+++GO:0008285///negative regulation of cell proliferation+++GO:0010572///positive regulation of platelet activation+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0016311///dephosphorylation+++GO:0030155///regulation of cell adhesion+++GO:0030183///B cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042593///glucose homeostasis+++GO:0043116///negative regulation of vascular permeability+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0045785///positive regulation of cell adhesion+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048709///oligodendrocyte differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050918///positive chemotaxis+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity+++GO:2000272///negative regulation of signaling receptor activity 19272 19272 'Ptprk' mRNA 926 968 965 9.66 9.52 10.06 8.09 8.52 8.63 9.746666667 8.413333333 1000 970 984 953 984.6666667 0.787259291 0.034293393 GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031256///leading edge membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008013///beta-catenin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0045295///gamma-catenin binding "GO:0006470///protein dephosphorylation+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016311///dephosphorylation+++GO:0016477///cell migration+++GO:0030217///T cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0031175///neuron projection development+++GO:0034394///protein localization to cell surface+++GO:0034614///cellular response to reactive oxygen species+++GO:0034644///cellular response to UV+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048041///focal adhesion assembly" 19273 19273 'Ptpru' mRNA 2741 2835 2525 27.35 27.91 27.02 10.36 8.02 8.31 27.42666667 8.896666667 1187 908 928 2700.333333 1007.666667 1.19E-59 -1.434726056 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008013///beta-catenin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030695///GTPase regulator activity GO:0006470///protein dephosphorylation+++GO:0007155///cell adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0016311///dephosphorylation+++GO:0030154///cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0031100///animal organ regeneration+++GO:0034109///homotypic cell-cell adhesion+++GO:0034394///protein localization to cell surface+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0051384///response to glucocorticoid+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin 192734 192734 'Lrrc75b' mRNA 534 573.09 368.7 6.33 6.8 4.75 3.11 4.19 2.95 5.96 3.416666667 297 382.52 272.02 491.93 317.18 2.87E-04 -0.634385211 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 19274 19274 'Ptprm' mRNA 3177 3255 2185 30.27 30.48 22.1 3.9 4.59 5.36 27.61666667 4.616666667 471 542 627 2872.333333 546.6666667 1.94E-87 -2.39501737 04514///Cell adhesion molecules+++04520///Adherens junction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0048471///perinuclear region of cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006470///protein dephosphorylation+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0009410///response to xenobiotic stimulus+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010842///retina layer formation+++GO:0016311///dephosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0031175///neuron projection development+++GO:0031290///retinal ganglion cell axon guidance+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042311///vasodilation+++GO:0042493///response to drug 19275 19275 'Ptprn' mRNA 18 23 18 0.28 0.35 0.3 0.85 0.75 0.88 0.31 0.826666667 63 54 63 19.66666667 60 7.37E-05 1.598874684 04940///Type I diabetes mellitus GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030507///spectrin binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0051020///GTPase binding GO:0000302///response to reactive oxygen species+++GO:0001553///luteinization+++GO:0006470///protein dephosphorylation+++GO:0009749///response to glucose+++GO:0016311///dephosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030073///insulin secretion+++GO:0032868///response to insulin+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0043627///response to estrogen+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051591///response to cAMP+++GO:1904692///positive regulation of type B pancreatic cell proliferation+++GO:1990502///dense core granule maturation 19276 19276 'Ptprn2' mRNA 50 68 62 0.57 0.76 0.77 0.04 0.02 0.03 0.7 0.03 4 2 3 60 3 9.60E-12 -4.336439459 04940///Type I diabetes mellitus GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043195///terminal bouton+++GO:0043235///receptor complex+++GO:0045202///synapse GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0007269///neurotransmitter secretion+++GO:0016311///dephosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus 19277 19277 'Ptpro' mRNA 60 75 80 0.76 0.95 1.09 4.8 4.13 4.49 0.933333333 4.473333333 422 353 380 71.66666667 385 3.78E-38 2.410086408 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0043197///dendritic spine+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017147///Wnt-protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding GO:0000902///cell morphogenesis+++GO:0002548///monocyte chemotaxis+++GO:0003093///regulation of glomerular filtration+++GO:0003105///negative regulation of glomerular filtration+++GO:0006470///protein dephosphorylation+++GO:0007411///axon guidance+++GO:0016311///dephosphorylation+++GO:0030032///lamellipodium assembly+++GO:0032835///glomerulus development+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0036060///slit diaphragm assembly+++GO:0050807///regulation of synapse organization+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 192775 192775 'Kcnh6' mRNA 1710.96 1670.11 1641.05 16.38 15.71 16.69 7.99 8.13 8.16 16.26 8.093333333 975.61 969.07 964.9 1674.04 969.86 1.87E-24 -0.799849515 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071805///potassium ion transmembrane transport+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction 192786 192786 'Rapgef6' mRNA 1101 1023 1041 8.02 7.44 8.54 7.12 6.35 6.87 8 6.78 1014 945 1050 1055 1003 0.44083596 -0.085488653 04015///Rap1 signaling pathway+++04530///Tight junction GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030139///endocytic vesicle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding+++GO:0070300///phosphatidic acid binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0030033///microvillus assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0072659///protein localization to plasma membrane 19279 19279 'Ptprr' mRNA 26 15 18 0.42 0.26 0.4 0.21 0.28 0.3 0.36 0.263333333 11 16 16 19.66666667 14.33333333 0.529888445 -0.464698704 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding GO:0001701///in utero embryonic development+++GO:0006470///protein dephosphorylation+++GO:0010633///negative regulation of epithelial cell migration+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0038128///ERBB2 signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 19280 19280 'Ptprs' mRNA 2192.65 2159 1474 18.12 17.88 13.47 12.28 11.11 13.24 16.49 12.21 1641.03 1452.39 1717 1941.883333 1603.473333 0.016148721 -0.280456162 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0035374///chondroitin sulfate binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0006470///protein dephosphorylation+++GO:0007155///cell adhesion+++GO:0010977///negative regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0021510///spinal cord development+++GO:0021549///cerebellum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0022038///corpus callosum development+++GO:0030517///negative regulation of axon extension+++GO:0032687///negative regulation of interferon-alpha production+++GO:0032688///negative regulation of interferon-beta production+++GO:0034164///negative regulation of toll-like receptor 9 signaling pathway+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0048671///negative regulation of collateral sprouting+++GO:0048681///negative regulation of axon regeneration+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0061000///negative regulation of dendritic spine development+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 19281 19281 'Ptprt' mRNA 705 710 631 3.62 3.89 3.68 0.29 0.34 0.22 3.73 0.283333333 53 58 46 682 52.33333333 1.72E-109 -3.71380217 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0008013///beta-catenin binding+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019903///protein phosphatase binding+++GO:0042803///protein homodimerization activity+++GO:0045294///alpha-catenin binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0051393///alpha-actinin binding+++GO:0070097///delta-catenin binding+++GO:0097677///STAT family protein binding GO:0006470///protein dephosphorylation+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016311///dephosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0050807///regulation of synapse organization+++GO:0071354///cellular response to interleukin-6+++GO:1904893///negative regulation of STAT cascade+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 19283 19283 'Ptprz1' mRNA 4015 4422 4120 37.05 40.02 40.37 4.84 5.05 4.83 39.14666667 4.906666667 605 617 595 4185.666667 605.6666667 0 -2.800532403 05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031012///extracellular matrix+++GO:0031226///intrinsic component of plasma membrane+++GO:0032587///ruffle membrane+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0072534///perineuronal net+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017134///fibroblast growth factor binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006470///protein dephosphorylation+++GO:0007409///axonogenesis+++GO:0007413///axonal fasciculation+++GO:0007611///learning or memory+++GO:0008285///negative regulation of cell proliferation+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0031641///regulation of myelination+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048709///oligodendrocyte differentiation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:1900006///positive regulation of dendrite development+++GO:1900149///positive regulation of Schwann cell migration+++GO:1901216///positive regulation of neuron death+++GO:2000171///negative regulation of dendrite development+++GO:2001224///positive regulation of neuron migration 19285 19285 'Cavin1' mRNA 2939 2771 3290 50.06 46.44 59.43 92.79 83.64 94.15 51.97666667 90.19333333 6273 5516 6160 3000 5983 1.17E-30 0.978327378 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0019843///rRNA binding+++GO:0042134///rRNA primary transcript binding+++GO:0042802///identical protein binding "GO:0006353///DNA-templated transcription, termination+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006363///termination of RNA polymerase I transcription+++GO:0009303///rRNA transcription+++GO:0009306///protein secretion+++GO:2000147///positive regulation of cell motility" 192852 192852 'Lrrc3c' mRNA 38 49 38 2.77 3.53 2.94 0.25 0.26 0.26 3.08 0.256666667 4 4 4 41.66666667 4 7.68E-08 -3.389606796 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix 19286 19286 'Pts' mRNA 653.7 767 640.99 36.82 42.89 39.14 46.08 46.21 47.58 39.61666667 46.62333333 934 917 936.15 687.23 929.05 2.12E-05 0.42632661 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003874///6-pyruvoyltetrahydropterin synthase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006729///tetrahydrobiopterin biosynthetic process 19288 19288 'Ptx3' mRNA 75 76 38 2.23 2.23 1.2 2.3 2.7 3.05 1.886666667 2.683333333 89 102 114 63 101.6666667 0.032630421 0.691950713 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0001849///complement component C1q binding+++GO:0001872///(1->3)-beta-D-glucan binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046790///virion binding GO:0001550///ovarian cumulus expansion+++GO:0001878///response to yeast+++GO:0008228///opsonization+++GO:0030198///extracellular matrix organization+++GO:0044793///negative regulation by host of viral process+++GO:0044869///negative regulation by host of viral exo-alpha-sialidase activity+++GO:0044871///negative regulation by host of viral glycoprotein metabolic process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0046597///negative regulation of viral entry into host cell+++GO:0050766///positive regulation of phagocytosis+++GO:1903016///negative regulation of exo-alpha-sialidase activity+++GO:1903019///negative regulation of glycoprotein metabolic process 19289 19289 'Igdcc3' mRNA 401 336 334 4.92 4.07 4.34 2.73 2.44 2.67 4.443333333 2.613333333 256 223 243 357 240.6666667 1.67E-04 -0.580654065 GO:0005575///cellular_component+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0050885///neuromuscular process controlling balance+++GO:0098609///cell-cell adhesion 192897 192897 'Itgb4' mRNA 1040 1157 879 9.87 10.46 8.9 11.89 11.31 11.62 9.743333333 11.60666667 1407 1273 1318 1025.333333 1332.666667 7.44E-05 0.370135397 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005604///basement membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0008305///integrin complex+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0031252///cell leading edge+++GO:0031965///nuclear membrane+++GO:0043235///receptor complex GO:0001664///G protein-coupled receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0031994///insulin-like growth factor I binding+++GO:0038132///neuregulin binding GO:0006914///autophagy+++GO:0007154///cell communication+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0009611///response to wounding+++GO:0016477///cell migration+++GO:0022011///myelination in peripheral nervous system+++GO:0031581///hemidesmosome assembly+++GO:0032290///peripheral nervous system myelin formation+++GO:0033627///cell adhesion mediated by integrin+++GO:0035878///nail development+++GO:0043589///skin morphogenesis+++GO:0046847///filopodium assembly+++GO:0048333///mesodermal cell differentiation+++GO:0048870///cell motility+++GO:0061450///trophoblast cell migration 19290 19290 'Pura' mRNA 1650.45 1650.07 1479.52 7.2 7.06 7.19 7.06 6.7 7.52 7.15 7.093333333 1757.32 1559.11 1732.69 1593.346667 1683.04 0.462613512 0.068155822 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0043025///neuronal cell body+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0032422///purine-rich negative regulatory element binding+++GO:0046332///SMAD binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046651///lymphocyte proliferation+++GO:0050673///epithelial cell proliferation+++GO:0098963///dendritic transport of messenger ribonucleoprotein complex" 19291 19291 'Purb' mRNA 2012 2015 1874 12.47 12.27 12.32 10.28 8.63 10.11 12.35333333 9.673333333 1911 1567 1821 1967 1766.333333 0.051163529 -0.167622819 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0032422///purine-rich negative regulatory element binding+++GO:0046332///SMAD binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 19293 19293 'Pvalb' mRNA 471 462 521 30.96 30 36.29 3.53 5.6 4.39 32.41666667 4.506666667 61 95 74 484.6666667 76.66666667 1.18E-46 -2.673255187 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0010467///gene expression+++GO:0090102///cochlea development+++GO:0098976///excitatory chemical synaptic transmission+++GO:0098977///inhibitory chemical synaptic transmission 19294 19294 'Nectin2' mRNA 1928 1968 1844 43.73 44.7 44.93 49.71 50.35 50.02 44.45333333 50.02666667 2458 2393 2342 1913.333333 2397.666667 2.87E-06 0.314173374 04514///Cell adhesion molecules+++04520///Adherens junction+++05168///Herpes simplex virus 1 infection GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045503///dynein light chain binding+++GO:0050839///cell adhesion molecule binding GO:0001675///acrosome assembly+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0002891///positive regulation of immunoglobulin mediated immune response+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007286///spermatid development+++GO:0007289///spermatid nucleus differentiation+++GO:0009566///fertilization+++GO:0016477///cell migration+++GO:0019062///virion attachment to host cell+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0030382///sperm mitochondrion organization+++GO:0032990///cell part morphogenesis+++GO:0033005///positive regulation of mast cell activation+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0044406///adhesion of symbiont to host+++GO:0044782///cilium organization+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046596///regulation of viral entry into host cell+++GO:0046718///viral entry into host cell+++GO:0046814///coreceptor-mediated virion attachment to host cell+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051654///establishment of mitochondrion localization+++GO:0060370///susceptibility to T cell mediated cytotoxicity+++GO:0098609///cell-cell adhesion 192950 192950 'Nacad' mRNA 137 122 105 1.5 1.31 1.22 0.54 0.19 0.14 1.343333333 0.29 52 20 14 121.3333333 28.66666667 4.21E-08 -2.098728645 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005854///nascent polypeptide-associated complex GO:0051082///unfolded protein binding GO:0006612///protein targeting to membrane+++GO:0015031///protein transport 192970 192970 'Dhrs11' mRNA 277 304 217 11.66 12.61 9.69 10.29 12.86 11.46 11.32 11.53666667 281 342 303 266 308.6666667 0.266909544 0.210191992 00140///Steroid hormone biosynthesis GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0000166///nucleotide binding+++GO:0000253///3-keto sterol reductase activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0072555///17-beta-ketosteroid reductase activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity+++GO:0102176///cycloeucalenone reductase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0008202///steroid metabolic process 192976 192976 'Lrrc75a' mRNA 187 167 145 6.3 5.67 5.21 3.34 2.94 3.05 5.726666667 3.11 113 97 99 166.3333333 103 0.001498385 -0.701182846 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 19298 19298 'Pex19' mRNA 1406 1357 1467 24.63 23.38 27.31 27.1 26.77 25.68 25.10666667 26.51666667 1781 1719 1634 1410 1711.333333 0.002740788 0.265028413 04146///Peroxisome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0033328///peroxisome membrane targeting sequence binding+++GO:0036105///peroxisome membrane class-1 targeting sequence binding+++GO:0047485///protein N-terminus binding+++GO:0051117///ATPase binding GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0016557///peroxisome membrane biogenesis+++GO:0016559///peroxisome fission+++GO:0045046///protein import into peroxisome membrane+++GO:0050821///protein stabilization+++GO:0061077///chaperone-mediated protein folding+++GO:0072321///chaperone-mediated protein transport+++GO:0072663///establishment of protein localization to peroxisome+++GO:1900131///negative regulation of lipid binding 192986 192986 'Cyb5d2' mRNA 805.51 737.34 623.22 18.97 17.1 15.57 8.85 10.16 10.85 17.21333333 9.953333333 432.03 484.27 512.95 722.0233333 476.4166667 7.74E-07 -0.607196415 GO:0005576///extracellular region+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0020037///heme binding GO:0007399///nervous system development+++GO:0045666///positive regulation of neuron differentiation 19299 19299 'Abcd3' mRNA 2219 2382 2080 33.85 35.71 33.61 32.5 29.33 30.42 34.39 30.75 2447 2153 2221 2227 2273.666667 0.860694977 0.018831228 02010///ABC transporters+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0047617///acyl-CoA hydrolase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006699///bile acid biosynthetic process+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0014070///response to organic cyclic compound+++GO:0015721///bile acid and bile salt transport+++GO:0015910///peroxisomal long-chain fatty acid import+++GO:0042493///response to drug+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0055085///transmembrane transport+++GO:1903512///phytanic acid metabolic process 19300 19300 'Abcd4' mRNA 449.35 421.62 448.53 9.72 9.07 10.34 7.99 8.41 8.29 9.71 8.23 423.38 429.15 421.07 439.8333333 424.5333333 0.714677964 -0.063115949 02010///ABC transporters+++04146///Peroxisome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005524///ATP binding+++GO:0015420///cobalamin-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006635///fatty acid beta-oxidation+++GO:0007031///peroxisome organization+++GO:0009235///cobalamin metabolic process+++GO:0015889///cobalamin transport+++GO:0015910///peroxisomal long-chain fatty acid import+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0055085///transmembrane transport+++GO:1990830///cellular response to leukemia inhibitory factor 193003 193003 'Pirt' mRNA 2 6 4 0.04 0.08 0.06 0 0 0 0.06 0 0 0 0 4 0 0.043331342 -4.452153812 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0044325///ion channel binding+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0009408///response to heat+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048266///behavioral response to pain+++GO:2001259///positive regulation of cation channel activity 19301 19301 'Pxmp2' mRNA 403 396 341 24.89 25.11 23.19 20.28 21.02 20.67 24.39666667 20.65666667 348 356 368 380 357.3333333 0.561348178 -0.097544252 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0046942///carboxylic acid transport 19302 19302 'Pex2' mRNA 1560 1577 1682 41.49 41.5 48.17 42.65 45.49 43.64 43.72 43.92666667 1792 1871 1807 1606.333333 1823.333333 0.066356128 0.169088202 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016593///Cdc73/Paf1 complex GO:0046872///metal ion binding GO:0000038///very long-chain fatty acid metabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006635///fatty acid beta-oxidation+++GO:0006699///bile acid biosynthetic process+++GO:0007031///peroxisome organization+++GO:0007399///nervous system development+++GO:0016558///protein import into peroxisome matrix+++GO:0031648///protein destabilization+++GO:0042632///cholesterol homeostasis+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation 19303 19303 'Pxn' mRNA 2182 2410 1842 31.48 34.16 28.2 32.03 33.69 31.96 31.28 32.56 2545 2619 2461 2144.666667 2541.666667 0.004042255 0.23819997 04062///Chemokine signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031252///cell leading edge GO:0003712///transcription coregulator activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0017166///vinculin binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0038191///neuropilin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051435///BH4 domain binding "GO:0000187///activation of MAPK activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006928///movement of cell or subcellular component+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008360///regulation of cell shape+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030032///lamellipodium assembly+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043410///positive regulation of MAPK cascade+++GO:0043542///endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0045860///positive regulation of protein kinase activity+++GO:0048041///focal adhesion assembly+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060396///growth hormone receptor signaling pathway+++GO:1901652///response to peptide" 193034 193034 'Trpv1' mRNA 4 9 4 0.06 0.13 0.06 0.03 0.04 0 0.083333333 0.023333333 2 3 0 5.666666667 1.666666667 0.261870749 -1.76403437 04080///Neuroactive ligand-receptor interaction+++04750///Inflammatory mediator regulation of TRP channels GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0000166///nucleotide binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005231///excitatory extracellular ligand-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008324///cation transmembrane transporter activity+++GO:0015276///ligand-gated ion channel activity+++GO:0015278///calcium-release channel activity+++GO:0017081///chloride channel regulator activity+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding+++GO:0097603///temperature-gated ion channel activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001659///temperature homeostasis+++GO:0001660///fever generation+++GO:0001774///microglial cell activation+++GO:0002024///diet induced thermogenesis+++GO:0002790///peptide secretion+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006629///lipid metabolic process+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006954///inflammatory response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009268///response to pH+++GO:0009408///response to heat+++GO:0010243///response to organonitrogen compound+++GO:0010459///negative regulation of heart rate+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0014047///glutamate secretion+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0034605///cellular response to heat+++GO:0042637///catagen+++GO:0043065///positive regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0050954///sensory perception of mechanical stimulus+++GO:0050955///thermoception+++GO:0050960///detection of temperature stimulus involved in thermoception+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050968///detection of chemical stimulus involved in sensory perception of pain+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051289///protein homotetramerization+++GO:0055085///transmembrane transport+++GO:0060079///excitatory postsynaptic potential+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0060454///positive regulation of gastric acid secretion+++GO:0070588///calcium ion transmembrane transport+++GO:0071312///cellular response to alkaloid+++GO:0071318///cellular response to ATP+++GO:0071345///cellular response to cytokine stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071468///cellular response to acidic pH+++GO:0071502///cellular response to temperature stimulus+++GO:0090212///negative regulation of establishment of blood-brain barrier+++GO:0098703///calcium ion import across plasma membrane+++GO:1901594///response to capsazepine+++GO:1990090///cellular response to nerve growth factor stimulus 193043 193043 'Zfp3' mRNA 351 424 337 11.08 13.19 11.29 7.66 9.57 7.15 11.85333333 8.126666667 279 340 252 370.6666667 290.3333333 0.035356832 -0.359779308 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 19305 19305 'Pex5' mRNA 1068 1184 1167 18.94 20.74 22.01 20.46 19.83 19.12 20.56333333 19.80333333 1327 1247 1185 1139.666667 1253 0.237542904 0.123144018 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0000268///peroxisome targeting sequence binding+++GO:0005052///peroxisome matrix targeting signal-1 binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0033328///peroxisome membrane targeting sequence binding+++GO:0047485///protein N-terminus binding "GO:0000038///very long-chain fatty acid metabolic process+++GO:0001764///neuron migration+++GO:0006625///protein targeting to peroxisome+++GO:0006635///fatty acid beta-oxidation+++GO:0007005///mitochondrion organization+++GO:0007006///mitochondrial membrane organization+++GO:0007029///endoplasmic reticulum organization+++GO:0007031///peroxisome organization+++GO:0008299///isoprenoid biosynthetic process+++GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix+++GO:0016560///protein import into peroxisome matrix, docking+++GO:0016561///protein import into peroxisome matrix, translocation+++GO:0021795///cerebral cortex cell migration+++GO:0021895///cerebral cortex neuron differentiation+++GO:0031333///negative regulation of protein complex assembly+++GO:0040018///positive regulation of multicellular organism growth+++GO:0044255///cellular lipid metabolic process+++GO:0045046///protein import into peroxisome membrane+++GO:0048468///cell development+++GO:0050905///neuromuscular process+++GO:0051262///protein tetramerization" 19309 19309 'Pygm' mRNA 135 153 164 2.59 2.89 3.34 1.29 1.26 1.65 2.94 1.4 77 74 96 150.6666667 82.33333333 3.10E-04 -0.886598294 00500///Starch and sucrose metabolism+++04217///Necroptosis+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance GO:0005737///cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004645///phosphorylase activity+++GO:0008184///glycogen phosphorylase activity+++GO:0016208///AMP binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030170///pyridoxal phosphate binding+++GO:0030246///carbohydrate binding+++GO:0097159///organic cyclic compound binding+++GO:0102250///linear malto-oligosaccharide phosphorylase activity+++GO:0102499///SHG alpha-glucan phosphorylase activity" GO:0001666///response to hypoxia+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0008152///metabolic process+++GO:0010033///response to organic substance+++GO:0051591///response to cAMP 193116 193116 'Slu7' mRNA 1664 1567 1544 24.26 22.43 23.83 21.47 21.93 20.1 23.50666667 21.16666667 1692 1691 1539 1591.666667 1640.666667 0.769837997 0.031992506 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071013///catalytic step 2 spliceosome GO:0000386///second spliceosomal transesterification activity+++GO:0008270///zinc ion binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0046872///metal ion binding "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000389///mRNA 3'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006886///intracellular protein transport+++GO:0008380///RNA splicing+++GO:0034605///cellular response to heat" 19317 19317 'Qk' mRNA 4964 4779 4540 46.29 43.8 45.08 39.15 32.32 38.45 45.05666667 36.64 4668 3784 4455 4761 4302.333333 0.039262973 -0.158900439 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045202///synapse GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0017124///SH3 domain binding "GO:0001570///vasculogenesis+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007286///spermatid development+++GO:0008366///axon ensheathment+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0042552///myelination+++GO:0042692///muscle cell differentiation+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048255///mRNA stabilization+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0051028///mRNA transport+++GO:0061158///3'-UTR-mediated mRNA destabilization" 19324 19324 'Rab1a' mRNA 4861 4916 4593 94.14 93.71 94.36 123.83 122.14 118.27 94.07 121.4133333 7356 7086 6803 4790 7081.666667 3.35E-25 0.552634068 04140///Autophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05134///Legionellosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0000045///autophagosome assembly+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016477///cell migration+++GO:0019068///virion assembly+++GO:0030252///growth hormone secretion+++GO:0032402///melanosome transport+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042742///defense response to bacterium+++GO:0047496///vesicle transport along microtubule+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:1903020///positive regulation of glycoprotein metabolic process 19325 19325 'Rab10' mRNA 1828 2036 754 28.29 31 12.38 19.47 21.38 20.19 23.89 20.34666667 1448 1553 1454 1539.333333 1485 0.939287648 -0.042438548 04144///Endocytosis+++04152///AMPK signaling pathway GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032593///insulin-responsive compartment+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070382///exocytic vesicle+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0031489///myosin V binding+++GO:0051021///GDP-dissociation inhibitor binding GO:0006886///intracellular protein transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007409///axonogenesis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016197///endosomal transport+++GO:0017157///regulation of exocytosis+++GO:0019882///antigen processing and presentation+++GO:0030859///polarized epithelial cell differentiation+++GO:0032869///cellular response to insulin stimulus+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045055///regulated exocytosis+++GO:0045200///establishment of neuroblast polarity+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0072659///protein localization to plasma membrane+++GO:0090150///establishment of protein localization to membrane+++GO:0097051///establishment of protein localization to endoplasmic reticulum membrane+++GO:1903361///protein localization to basolateral plasma membrane 19326 19326 'Rab11b' mRNA 5856.94 5990.37 5797.06 140.54 142.06 146.53 133.47 134.88 132.86 143.0433333 133.7366667 6146.7 5997.15 5925 5881.456667 6022.95 0.772945073 0.022134015 04144///Endocytosis+++04152///AMPK signaling pathway+++04962///Vasopressin-regulated water reabsorption+++05164///Influenza A GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030670///phagocytic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0031489///myosin V binding GO:0001881///receptor recycling+++GO:0006887///exocytosis+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0032402///melanosome transport+++GO:0032456///endocytic recycling+++GO:0033572///transferrin transport+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0044070///regulation of anion transport+++GO:0045054///constitutive secretory pathway+++GO:0045055///regulated exocytosis+++GO:0071468///cellular response to acidic pH+++GO:0090150///establishment of protein localization to membrane+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:2000008///regulation of protein localization to cell surface+++GO:2001135///regulation of endocytic recycling 19328 19328 'Rab12' mRNA 229 224 205 7.44 7.36 7.21 8.34 7.29 7.38 7.336666667 7.67 288 248 249 219.3333333 261.6666667 0.177066656 0.242990029 GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0032593///insulin-responsive compartment+++GO:0045335///phagocytic vesicle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006904///vesicle docking involved in exocytosis+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016239///positive regulation of macroautophagy+++GO:0017157///regulation of exocytosis+++GO:0032482///Rab protein signal transduction+++GO:0032869///cellular response to insulin stimulus+++GO:0044257///cellular protein catabolic process+++GO:0071346///cellular response to interferon-gamma+++GO:0072659///protein localization to plasma membrane 193286 193286 'BC049762' mRNA 11 12 9 0.8 1.05 0.75 0.8 0.95 0.48 0.866666667 0.743333333 15 16 7 10.66666667 12.66666667 0.81278904 0.239972053 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 19329 19329 'Rab17' mRNA 473 562 460 15.68 18.35 16.19 10.25 10.53 11.48 16.74 10.75333333 360 347 381 498.3333333 362.6666667 3.80E-04 -0.467879175 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030139///endocytic vesicle+++GO:0030425///dendrite+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0002415///immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0030100///regulation of endocytosis+++GO:0032401///establishment of melanosome localization+++GO:0032402///melanosome transport+++GO:0032456///endocytic recycling+++GO:0045056///transcytosis+++GO:0046847///filopodium assembly+++GO:0050773///regulation of dendrite development+++GO:0051489///regulation of filopodium assembly+++GO:0051963///regulation of synapse assembly+++GO:0060271///cilium assembly 19330 19330 'Rab18' mRNA 3999 3984 3908 59.09 57.91 61.26 57.87 54.26 58.02 59.42 56.71666667 4507 4128 4376 3963.666667 4337 0.073515857 0.11710159 GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0045202///synapse+++GO:0071782///endoplasmic reticulum tubular network GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0001654///eye development+++GO:0006886///intracellular protein transport+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0034389///lipid droplet organization+++GO:0051170///import into nucleus+++GO:0071786///endoplasmic reticulum tubular network organization 19331 19331 'Rab19' mRNA 537 508 508 20.65 19.06 19.89 12.01 11.45 10.49 19.86666667 11.31666667 366 324 314 517.6666667 334.6666667 4.46E-07 -0.642319063 GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0000045///autophagosome assembly+++GO:0006886///intracellular protein transport 19332 19332 'Rab20' mRNA 957 978 895 39.37 39.91 39.82 46.5 48.75 47.56 39.7 47.60333333 1296 1312 1290 943.3333333 1299.333333 5.08E-08 0.45146106 GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0071346///cellular response to interferon-gamma+++GO:0090383///phagosome acidification+++GO:0090385///phagosome-lysosome fusion 19334 19334 'Rab22a' mRNA 159 177 112 4.77 5.23 3.56 5.16 5.53 5.79 4.52 5.493333333 198 207 215 149.3333333 206.6666667 0.028846451 0.465103162 04144///Endocytosis GO:0001726///ruffle+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0097494///regulation of vesicle size 19335 19335 'Rab23' mRNA 472 581 575 6.51 8.19 8.92 5.59 6.06 6.09 7.873333333 5.913333333 440 463 441 542.6666667 448 0.040458676 -0.290015982 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0000045///autophagosome assembly+++GO:0001843///neural tube closure+++GO:0006886///intracellular protein transport+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0015031///protein transport+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042733///embryonic digit morphogenesis+++GO:0045861///negative regulation of proteolysis+++GO:0046039///GTP metabolic process+++GO:0060271///cilium assembly+++GO:0097094///craniofacial suture morphogenesis 19336 19336 'Rab24' mRNA 1930 1908 246 75.93 74.59 8.92 8.04 15.71 25.52 53.14666667 16.42333333 264 478 712 1361.333333 484.6666667 0.14280777 -1.462496343 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030139///endocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0015031///protein transport 19337 19337 'Rab33a' mRNA 134.08 128.28 127.98 5.69 5.06 5.67 0.95 1.1 1.28 5.473333333 1.11 30.57 29.12 34.06 130.1133333 31.25 4.18E-13 -2.076376436 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0019882///antigen processing and presentation+++GO:0032482///Rab protein signal transduction 19338 19338 'Rab33b' mRNA 1120.02 1201.34 1208.76 17.47 18.43 20 13.17 13.68 14.16 18.63333333 13.67 971.86 985.97 1012.18 1176.706667 990.0033333 0.006400299 -0.262707943 04140///Autophagy - animal GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0016020///membrane+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0000045///autophagosome assembly+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0034067///protein localization to Golgi apparatus+++GO:0048705///skeletal system morphogenesis+++GO:1903358///regulation of Golgi organization+++GO:1903434///negative regulation of constitutive secretory pathway+++GO:2000156///regulation of retrograde vesicle-mediated transport, Golgi to ER" 193385 193385 'Ripor2' mRNA 1636.2 1704.48 1594.17 16.06 16.54 16.52 5.62 4.51 5.1 16.37333333 5.076666667 646.36 519.54 581.01 1644.95 582.3033333 5.33E-63 -1.511625398 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030175///filopodium+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0060171///stereocilium membrane GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0071889///14-3-3 protein binding GO:0006935///chemotaxis+++GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0007517///muscle organ development+++GO:0007605///sensory perception of sound+++GO:0009968///negative regulation of signal transduction+++GO:0030154///cell differentiation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0042130///negative regulation of T cell proliferation+++GO:0045184///establishment of protein localization+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048741///skeletal muscle fiber development+++GO:0051260///protein homooligomerization+++GO:0051491///positive regulation of filopodium assembly+++GO:0051726///regulation of cell cycle+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071260///cellular response to mechanical stimulus+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1901673///regulation of mitotic spindle assembly+++GO:1901741///positive regulation of myoblast fusion+++GO:1903904///negative regulation of establishment of T cell polarity+++GO:1905872///negative regulation of protein localization to cell leading edge+++GO:1990869///cellular response to chemokine+++GO:2000114///regulation of establishment of cell polarity+++GO:2000391///positive regulation of neutrophil extravasation+++GO:2000405///negative regulation of T cell migration+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity 19339 19339 'Rab3a' mRNA 2195 2348 2010 97.45 103.07 94.84 35.06 35.42 34.63 98.45333333 35.03666667 906 893 866 2184.333333 888.3333333 3.41E-68 -1.307635116 04721///Synaptic vesicle cycle+++04911///Insulin secretion GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0043229///intracellular organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0001671///ATPase activator activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding+++GO:0030742///GTP-dependent protein binding+++GO:0031489///myosin V binding+++GO:0051021///GDP-dissociation inhibitor binding+++GO:0051117///ATPase binding GO:0001778///plasma membrane repair+++GO:0003016///respiratory system process+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007005///mitochondrion organization+++GO:0007274///neuromuscular synaptic transmission+++GO:0007409///axonogenesis+++GO:0009306///protein secretion+++GO:0009791///post-embryonic development+++GO:0010807///regulation of synaptic vesicle priming+++GO:0014059///regulation of dopamine secretion+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0016188///synaptic vesicle maturation+++GO:0017156///calcium ion regulated exocytosis+++GO:0017157///regulation of exocytosis+++GO:0030324///lung development+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0032418///lysosome localization+++GO:0036465///synaptic vesicle recycling+++GO:0045055///regulated exocytosis+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048489///synaptic vesicle transport+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0050790///regulation of catalytic activity+++GO:0050975///sensory perception of touch+++GO:0051602///response to electrical stimulus+++GO:0060478///acrosomal vesicle exocytosis+++GO:0061670///evoked neurotransmitter secretion+++GO:0072659///protein localization to plasma membrane+++GO:0097091///synaptic vesicle clustering+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1903307///positive regulation of regulated secretory pathway+++GO:1905684///regulation of plasma membrane repair+++GO:2000300///regulation of synaptic vesicle exocytosis 19340 19340 'Rab3d' mRNA 459 477 469 6.48 6.61 7.01 10.55 11.35 10.51 6.7 10.80333333 859 902 829 468.3333333 863.3333333 1.40E-16 0.870602947 04972///Pancreatic secretion GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0042588///zymogen granule+++GO:0099503///secretory vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030742///GTP-dependent protein binding+++GO:0031489///myosin V binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0018125///peptidyl-cysteine methylation+++GO:0045453///bone resorption+++GO:0072659///protein localization to plasma membrane+++GO:1903307///positive regulation of regulated secretory pathway 19341 19341 'Rab4a' mRNA 1140 1098 1175 47.96 45.54 52.41 33.64 32.11 32.25 48.63666667 32.66666667 920 859 852 1137.666667 877 4.68E-05 -0.389758295 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0031982///vesicle+++GO:0032593///insulin-responsive compartment+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0098837///postsynaptic recycling endosome+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0001671///ATPase activator activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0019905///syntaxin binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0051117///ATPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0019882///antigen processing and presentation+++GO:0030100///regulation of endocytosis+++GO:0032482///Rab protein signal transduction+++GO:0050790///regulation of catalytic activity 19342 19342 'Rab4b' mRNA 1000 1029 952 52.76 53.63 53.29 67.59 77.37 67.77 53.22666667 70.91 1470 1641 1425 993.6666667 1512 2.80E-11 0.595616011 GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0032593///insulin-responsive compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0015031///protein transport+++GO:0030100///regulation of endocytosis+++GO:0032482///Rab protein signal transduction+++GO:0046323///glucose import 19344 19344 'Rab5b' mRNA 2938.73 3116.12 2401.01 49.9 51.94 43.22 31.98 28.96 29.87 48.35333333 30.27 2183.81 1929.89 1980.91 2818.62 2031.536667 1.15E-09 -0.480884031 04014///Ras signaling pathway+++04144///Endocytosis+++04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection+++05146///Amoebiasis+++05152///Tuberculosis GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031901///early endosome membrane+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0030742///GTP-dependent protein binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0019882///antigen processing and presentation+++GO:0030100///regulation of endocytosis+++GO:0048227///plasma membrane to endosome transport 19345 19345 'Rab5c' mRNA 219 261 153 6.52 7.65 4.83 11.84 9.72 11.41 6.333333333 10.99 457 366 426 211 416.3333333 1.75E-08 0.975681765 04014///Ras signaling pathway+++04144///Endocytosis+++04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection+++05146///Amoebiasis+++05152///Tuberculosis GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042470///melanosome+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0030100///regulation of endocytosis+++GO:0048227///plasma membrane to endosome transport 193452 193452 'Zfp184' mRNA 158 177 163 3.15 3.47 3.39 1.18 0.64 1.16 3.336666667 0.993333333 67 38 67 166 57.33333333 2.57E-09 -1.548228502 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 19346 19346 'Rab6a' mRNA 3461 3668 3334 58.88 61.4 60.16 56.77 55.44 57.11 60.14666667 56.44 3840 3663 3741 3487.666667 3748 0.154520789 0.092744758 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0070381///endosome to plasma membrane transport vesicle+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0001671///ATPase activator activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019904///protein domain specific binding+++GO:0031489///myosin V binding+++GO:0047485///protein N-terminus binding+++GO:0051117///ATPase binding "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0018125///peptidyl-cysteine methylation+++GO:0019882///antigen processing and presentation+++GO:0034067///protein localization to Golgi apparatus+++GO:0034498///early endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050790///regulation of catalytic activity" 19347 19347 'Dennd5a' mRNA 1304 1380 1391 14.06 14.63 15.91 15.78 14.28 15.36 14.86666667 15.14 1685 1487 1588 1358.333333 1586.666667 0.018407725 0.210015052 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030904///retromer complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding "GO:0010977///negative regulation of neuron projection development+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050790///regulation of catalytic activity" 19348 19348 'Kif20a' mRNA 8.06 28.3 32.85 0.13 0.44 0.53 5.91 5.92 5.56 0.366666667 5.796666667 435.27 425.83 396.23 23.07 419.11 2.53E-16 4.183955722 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0045171///intercellular bridge GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0000281///mitotic cytokinesis+++GO:0001578///microtubule bundle formation+++GO:0007018///microtubule-based movement+++GO:0015031///protein transport+++GO:0032465///regulation of cytokinesis+++GO:0061952///midbody abscission 19349 19349 'Rab7' mRNA 8265 8681.92 8502.23 216.07 223.41 236.48 257.2 244.64 245.09 225.32 248.9766667 11277.59 10509.83 10442 8483.05 10743.14 9.53E-09 0.327458043 04137///Mitophagy - animal+++04140///Autophagy - animal+++04144///Endocytosis+++04145///Phagosome+++05132///Salmonella infection+++05146///Amoebiasis+++05152///Tuberculosis GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0032419///extrinsic component of lysosome membrane+++GO:0033162///melanosome membrane+++GO:0034045///phagophore assembly site membrane+++GO:0045335///phagocytic vesicle+++GO:0097208///alveolar lamellar body+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0031267///small GTPase binding+++GO:1905394///retromer complex binding "GO:0000045///autophagosome assembly+++GO:0006622///protein targeting to lysosome+++GO:0006629///lipid metabolic process+++GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0007174///epidermal growth factor catabolic process+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016042///lipid catabolic process+++GO:0019076///viral release from host cell+++GO:0022615///protein to membrane docking+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045022///early endosome to late endosome transport+++GO:0045453///bone resorption+++GO:0045732///positive regulation of protein catabolic process+++GO:0048524///positive regulation of viral process+++GO:0051650///establishment of vesicle localization+++GO:0061724///lipophagy+++GO:0090383///phagosome acidification+++GO:0090385///phagosome-lysosome fusion+++GO:0099638///endosome to plasma membrane protein transport+++GO:1903542///negative regulation of exosomal secretion+++GO:1903543///positive regulation of exosomal secretion" 19352 19352 'Rabggtb' mRNA 636 630 557 28.58 28.09 26.47 32.62 29.99 37.65 27.71333333 33.42 832 745 932 607.6666667 836.3333333 6.05E-05 0.450677269 GO:0005968///Rab-protein geranylgeranyltransferase complex GO:0003824///catalytic activity+++GO:0004659///prenyltransferase activity+++GO:0004663///Rab geranylgeranyltransferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008318///protein prenyltransferase activity+++GO:0016740///transferase activity+++GO:0019840///isoprenoid binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0018342///protein prenylation+++GO:0018344///protein geranylgeranylation 19353 19353 'Rac1' mRNA 7118 7127 3677 175.96 173.56 96.45 132.45 234.22 210.63 148.6566667 192.4333333 6160 10636 9480 5974 8758.666667 0.158979943 0.560678618 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04972///Pancreatic secretion+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05100///Bacterial invasion of epithelial cells+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000139///Golgi membrane+++GO:0000242///pericentriolar material+++GO:0001891///phagocytic cup+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032587///ruffle membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane+++GO:0060091///kinocilium+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003924///GTPase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding+++GO:0031996///thioesterase binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding+++GO:0051022///Rho GDP-dissociation inhibitor binding+++GO:0051117///ATPase binding "GO:0001764///neuron migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002093///auditory receptor cell morphogenesis+++GO:0002551///mast cell chemotaxis+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0003382///epithelial cell morphogenesis+++GO:0006897///endocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0006935///chemotaxis+++GO:0006972///hyperosmotic response+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0008283///cell proliferation+++GO:0008360///regulation of cell shape+++GO:0008361///regulation of cell size+++GO:0010591///regulation of lamellipodium assembly+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010762///regulation of fibroblast migration+++GO:0010764///negative regulation of fibroblast migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0014041///regulation of neuron maturation+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0021894///cerebral cortex GABAergic interneuron development+++GO:0022604///regulation of cell morphogenesis+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030334///regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030865///cortical cytoskeleton organization+++GO:0030900///forebrain development+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031529///ruffle organization+++GO:0032707///negative regulation of interleukin-23 production+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0043652///engulfment of apoptotic cell+++GO:0045216///cell-cell junction organization+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0045453///bone resorption+++GO:0045740///positive regulation of DNA replication+++GO:0046425///regulation of JAK-STAT cascade+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048532///anatomical structure arrangement+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0048870///cell motility+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051492///regulation of stress fiber assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051668///localization within membrane+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051932///synaptic transmission, GABAergic+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060263///regulation of respiratory burst+++GO:0060999///positive regulation of dendritic spine development+++GO:0061344///regulation of cell adhesion involved in heart morphogenesis+++GO:0071260///cellular response to mechanical stimulus+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0071542///dopaminergic neuron differentiation+++GO:0072659///protein localization to plasma membrane+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090103///cochlea morphogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0097178///ruffle assembly+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902622///regulation of neutrophil migration+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:2000386///positive regulation of ovarian follicle development" 19354 19354 'Rac2' mRNA 221.76 214.39 206.62 4.01 3.81 3.96 42.52 42.76 43.99 3.926666667 43.09 2706.42 2658.22 2711.27 214.2566667 2691.97 0 3.644117712 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05020///Prion disease+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05416///Viral myocarditis+++05418///Fluid shear stress and atherosclerosis GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding GO:0006935///chemotaxis+++GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010810///regulation of cell-substrate adhesion+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042129///regulation of T cell proliferation+++GO:0043304///regulation of mast cell degranulation+++GO:0043652///engulfment of apoptotic cell+++GO:0045453///bone resorption+++GO:0050790///regulation of catalytic activity+++GO:0060263///regulation of respiratory burst+++GO:0060753///regulation of mast cell chemotaxis+++GO:0071593///lymphocyte aggregation+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:1902622///regulation of neutrophil migration 19355 19355 'Rad1' mRNA 419.08 441.36 408.04 15 15.87 16.27 13.61 11.79 13.54 15.71333333 12.98 415.51 348.83 379.65 422.8266667 381.33 0.270407937 -0.163404002 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0030896///checkpoint clamp complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0008853///exodeoxyribonuclease III activity+++GO:0016787///hydrolase activity GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051598///meiotic recombination checkpoint+++GO:0071479///cellular response to ionizing radiation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 19356 19356 'Rad17' mRNA 413 449 393 8.34 8.92 8.37 6.92 7.5 8.04 8.543333333 7.486666667 396 416 445 418.3333333 419 0.970792633 -0.007237635 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031389///Rad17 RFC-like complex" GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003689///DNA clamp loader activity+++GO:0005524///ATP binding GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0008156///negative regulation of DNA replication+++GO:0031573///intra-S DNA damage checkpoint+++GO:0033314///mitotic DNA replication checkpoint+++GO:0042325///regulation of phosphorylation 19357 19357 'Rad21' mRNA 872 907 763 13.39 13.75 12.47 14.44 12.71 13.39 13.20333333 13.51333333 1077 926 970 847.3333333 991 0.031486281 0.215683034 04110///Cell cycle "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0016363///nuclear matrix+++GO:0034990///nuclear mitotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex" GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007130///synaptonemal complex assembly+++GO:0007275///multicellular organism development+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0045841///negative regulation of mitotic metaphase/anaphase transition+++GO:0045876///positive regulation of sister chromatid cohesion+++GO:0051301///cell division+++GO:0071168///protein localization to chromatin+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange 19358 19358 'Rad23a' mRNA 1726.93 1606.37 1866.14 52.93 48.49 60.75 50.31 47.14 47.07 54.05666667 48.17333333 1868.77 1702.62 1686.66 1733.146667 1752.683333 0.998591786 -5.38E-04 03420///Nucleotide excision repair+++04141///Protein processing in endoplasmic reticulum GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle GO:0003684///damaged DNA binding+++GO:0019900///kinase binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0070628///proteasome binding+++GO:1990381///ubiquitin-specific protease binding GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031648///protein destabilization+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045787///positive regulation of cell cycle 19359 19359 'Rad23b' mRNA 700 705 171 9.94 9.85 2.58 4.13 4.65 5.38 7.456666667 4.72 335 368 422 525.3333333 375 0.529888445 -0.469919985 03420///Nucleotide excision repair+++04141///Protein processing in endoplasmic reticulum GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071942///XPC complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070628///proteasome binding "GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048568///embryonic organ development+++GO:0098761///cellular response to interleukin-7" 19360 19360 'Rad50' mRNA 478 465 443 4.95 4.73 4.87 6.47 5.88 5.33 4.85 5.893333333 719 639 574 462 644 1.12E-04 0.4667609 03440///Homologous recombination+++03450///Non-homologous end-joining+++04218///Cellular senescence "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016234///inclusion body+++GO:0030870///Mre11 complex+++GO:0035861///site of double-strand break+++GO:0045120///pronucleus+++GO:0048471///perinuclear region of cytoplasm" "GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003690///double-stranded DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding" GO:0000019///regulation of mitotic recombination+++GO:0000722///telomere maintenance via recombination+++GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007004///telomere maintenance via telomerase+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0031860///telomeric 3' overhang formation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0033674///positive regulation of kinase activity+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051276///chromosome organization+++GO:0051321///meiotic cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1904354///negative regulation of telomere capping 19361 19361 'Rad51' mRNA 81 70 55 2.14 1.82 1.54 6.56 5.82 4.83 1.833333333 5.736666667 286 248 204 68.66666667 246 1.19E-16 1.831890479 03440///Homologous recombination+++03460///Fanconi anemia pathway+++05200///Pathways in cancer+++05212///Pancreatic cancer "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0035861///site of double-strand break+++GO:0048471///perinuclear region of cytoplasm" GO:0000150///recombinase activity+++GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0070182///DNA polymerase binding GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000730///DNA recombinase assembly+++GO:0001932///regulation of protein phosphorylation+++GO:0006259///DNA metabolic process+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006312///mitotic recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007127///meiosis I+++GO:0007131///reciprocal meiotic recombination+++GO:0009636///response to toxic substance+++GO:0010165///response to X-ray+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0014070///response to organic cyclic compound+++GO:0031297///replication fork processing+++GO:0032200///telomere organization+++GO:0036297///interstrand cross-link repair+++GO:0042148///strand invasion+++GO:0042493///response to drug+++GO:0051106///positive regulation of DNA ligation+++GO:0051321///meiotic cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0071312///cellular response to alkaloid+++GO:0071479///cellular response to ionizing radiation+++GO:0071480///cellular response to gamma radiation+++GO:0072711///cellular response to hydroxyurea+++GO:0072719///cellular response to cisplatin+++GO:0072757///cellular response to camptothecin+++GO:1904631///response to glucoside+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange+++GO:1990426///mitotic recombination-dependent replication fork processing 19362 19362 'Rad51ap1' mRNA 4 14 5 0.12 0.41 0.16 2.32 2.98 2.59 0.23 2.63 87 110 97 7.666666667 98 6.75E-16 3.673602677 "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0032991///protein-containing complex" GO:0000217///DNA secondary structure binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0062037///D-loop DNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010845///positive regulation of reciprocal meiotic recombination+++GO:0036297///interstrand cross-link repair+++GO:0051321///meiotic cell cycle+++GO:0071479///cellular response to ionizing radiation+++GO:1905168///positive regulation of double-strand break repair via homologous recombination 19363 19363 'Rad51b' mRNA 191.92 230.08 182.75 5.74 6.97 5.94 4.81 5.2 4.76 6.216666667 4.923333333 187.37 186.03 177.34 201.5833333 183.58 0.529127799 -0.141624191 03440///Homologous recombination GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0033063///Rad51B-Rad51C-Rad51D-XRCC2 complex GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0001701///in utero embryonic development+++GO:0001832///blastocyst growth+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0061053///somite development 19364 19364 'Rad51d' mRNA 774.44 715.7 820 11.88 10.98 12.85 11.88 10.21 10.7 11.90333333 10.93 750 619 672 770.0466667 680.3333333 0.128644209 -0.194603596 03440///Homologous recombination "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0033063///Rad51B-Rad51C-Rad51D-XRCC2 complex" GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0043015///gamma-tubulin binding GO:0000722///telomere maintenance via recombination+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0036297///interstrand cross-link repair+++GO:0042148///strand invasion+++GO:0051276///chromosome organization+++GO:0051726///regulation of cell cycle 19365 19365 'Rad52' mRNA 342 354 375 10.81 11.23 12.78 8.32 7.89 8.92 11.60666667 8.376666667 298 280 315 357 297.6666667 0.079950618 -0.276380079 03440///Homologous recombination GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding GO:0000724///double-strand break repair via homologous recombination+++GO:0000730///DNA recombinase assembly+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006312///mitotic recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010792///DNA double-strand break processing involved in repair via single-strand annealing+++GO:0034599///cellular response to oxidative stress+++GO:0045002///double-strand break repair via single-strand annealing+++GO:2000819///regulation of nucleotide-excision repair 19366 19366 'Rad54l' mRNA 84.56 46.06 77.01 1.48 0.5 1.03 2.87 2.51 2.68 1.003333333 2.686666667 206.57 174.55 178.68 69.21 186.6 3.51E-08 1.412235492 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0015616///DNA translocase activity+++GO:0016787///hydrolase activity+++GO:0036310///annealing helicase activity+++GO:0046872///metal ion binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0008340///determination of adult lifespan+++GO:0009410///response to xenobiotic stimulus+++GO:0010212///response to ionizing radiation+++GO:0032508///DNA duplex unwinding+++GO:0042493///response to drug+++GO:0045003///double-strand break repair via synthesis-dependent strand annealing+++GO:0051276///chromosome organization 19367 19367 'Rad9a' mRNA 655.33 686.69 622.74 18.19 18.78 18.34 17.3 16.26 18.69 18.43666667 17.41666667 716.63 657.45 749.37 654.92 707.8166667 0.415593868 0.101307759 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030896///checkpoint clamp complex GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008408///3'-5' exonuclease activity+++GO:0008853///exodeoxyribonuclease III activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding GO:0000076///DNA replication checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009314///response to radiation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0071479///cellular response to ionizing radiation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage 193670 193670 'Rnf185' mRNA 1202 1213 1275 20.25 20.12 22.89 21.39 22.24 21 21.08666667 21.54333333 1460 1457 1387 1230 1434.666667 0.024141201 0.208328086 04141///Protein processing in endoplasmic reticulum GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0043130///ubiquitin binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0036503///ERAD pathway+++GO:0051865///protein autoubiquitination+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:1904294///positive regulation of ERAD pathway 19373 19373 'Rag1' mRNA 2 0 0 0.02 0 0 0.01 0.01 0.04 0.006666667 0.02 2 2 5 0.666666667 3 0.357493517 2.176155372 04068///FoxO signaling pathway+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097519///DNA recombinase complex+++GO:1905347///endodeoxyribonuclease complex GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990238///double-stranded DNA endodeoxyribonuclease activity GO:0002250///adaptive immune response+++GO:0002331///pre-B cell allelic exclusion+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0008152///metabolic process+++GO:0008542///visual learning+++GO:0010390///histone monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0030183///B cell differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0033151///V(D)J recombination+++GO:0043029///T cell homeostasis+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045580///regulation of T cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0048538///thymus development+++GO:0051865///protein autoubiquitination+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:2000822///regulation of behavioral fear response 193736 193736 'Zbtb12' mRNA 13 8 6 0.42 0.26 0.21 0.2 0.24 0.21 0.296666667 0.216666667 7 8 7 9 7.333333333 0.799406227 -0.298109828 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 19374 19374 'Rag2' mRNA 1 1 1 0.02 0.02 0.02 0.09 0.09 0.02 0.02 0.066666667 6 6 1 1 4.333333333 0.249909266 2.101448148 04068///FoxO signaling pathway+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097519///DNA recombinase complex "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0035091///phosphatidylinositol binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0002313///mature B cell differentiation involved in immune response+++GO:0002326///B cell lineage commitment+++GO:0002331///pre-B cell allelic exclusion+++GO:0002358///B cell homeostatic proliferation+++GO:0002360///T cell lineage commitment+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0016567///protein ubiquitination+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0033151///V(D)J recombination+++GO:0042742///defense response to bacterium+++GO:0046622///positive regulation of organ growth 193740 193740 'Hspa1a' mRNA 292.6 363.6 316.96 5.77 7.06 6.63 9.58 8.16 7.72 6.486666667 8.486666667 558.42 464.57 435.88 324.3866667 486.29 8.00E-05 0.572590839 03040///Spliceosome+++04010///MAPK signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04144///Endocytosis+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation+++04915///Estrogen signaling pathway+++05020///Prion disease+++05134///Legionellosis+++05145///Toxoplasmosis+++05162///Measles+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0016234///inclusion body+++GO:0016235///aggresome+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0002020///protease binding+++GO:0003714///transcription corepressor activity+++GO:0003725///double-stranded RNA binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0031249///denatured protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042826///histone deacetylase binding+++GO:0044183///protein binding involved in protein folding+++GO:0047485///protein N-terminus binding+++GO:0051059///NF-kappaB binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:0097718///disordered domain specific binding GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006402///mRNA catabolic process+++GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0007041///lysosomal transport+++GO:0008285///negative regulation of cell proliferation+++GO:0009408///response to heat+++GO:0016192///vesicle-mediated transport+++GO:0030308///negative regulation of cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0045666///positive regulation of neuron differentiation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0060548///negative regulation of cell death+++GO:0090063///positive regulation of microtubule nucleation+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:1901673///regulation of mitotic spindle assembly 193742 193742 'Abhd16a' mRNA 3247 3502 3511 94.6 100.43 108.13 63.64 69.36 62.02 101.0533333 65.00666667 2516 2669 2374 3420 2519.666667 6.96E-09 -0.453724453 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004620///phospholipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047372///acylglycerol lipase activity GO:0006629///lipid metabolic process+++GO:0006660///phosphatidylserine catabolic process+++GO:0052651///monoacylglycerol catabolic process+++GO:0098734///macromolecule depalmitoylation+++GO:1905344///prostaglandin catabolic process 19376 19376 'Rab34' mRNA 1737 1768 1702 67.57 69.36 72.84 67.08 71.27 67.94 69.92333333 68.76333333 1914 1958 1877 1735.666667 1916.333333 0.100377391 0.131337853 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0031985///Golgi cisterna+++GO:0042995///cell projection+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019001///guanyl nucleotide binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding GO:0006897///endocytosis+++GO:0007041///lysosomal transport+++GO:0015031///protein transport+++GO:0019882///antigen processing and presentation+++GO:0030030///cell projection organization+++GO:0032418///lysosome localization+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0071333///cellular response to glucose stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0090382///phagosome maturation+++GO:0090385///phagosome-lysosome fusion+++GO:1900426///positive regulation of defense response to bacterium+++GO:1905171///positive regulation of protein localization to phagocytic vesicle 19377 19377 'Rai1' mRNA 2031.2 2100.79 1714.36 10.09 10.25 8.6 6.44 5.76 5.92 9.646666667 6.04 1665.68 1384.49 1475.49 1948.783333 1508.553333 6.74E-06 -0.379314376 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0046872///metal ion binding "GO:0001501///skeletal system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032922///circadian regulation of gene expression+++GO:0040015///negative regulation of multicellular organism growth+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 19378 19378 'Aldh1a2' mRNA 1243 1190 1211 30.86 29.1 31.9 65.1 63.14 65.96 30.62 64.73333333 3015 2855 2957 1214.666667 2942.333333 6.48E-73 1.2636816 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm "GO:0001758///retinal dehydrogenase activity+++GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016918///retinal binding+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0042802///identical protein binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0001523///retinoid metabolic process+++GO:0001568///blood vessel development+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001936///regulation of endothelial cell proliferation+++GO:0001947///heart looping+++GO:0002138///retinoic acid biosynthetic process+++GO:0003007///heart morphogenesis+++GO:0006068///ethanol catabolic process+++GO:0007494///midgut development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009855///determination of bilateral symmetry+++GO:0009952///anterior/posterior pattern specification+++GO:0009954///proximal/distal pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0014032///neural crest cell development+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030392///fructosamine catabolic process+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0031016///pancreas development+++GO:0031076///embryonic camera-type eye development+++GO:0032355///response to estradiol+++GO:0033189///response to vitamin A+++GO:0034097///response to cytokine+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035799///ureter maturation+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042574///retinal metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048566///embryonic digestive tract development+++GO:0048738///cardiac muscle tissue development+++GO:0051289///protein homotetramerization+++GO:0060324///face development+++GO:0071300///cellular response to retinoic acid+++GO:0090242///retinoic acid receptor signaling pathway involved in somitogenesis+++GO:0110095///cellular detoxification of aldehyde 193796 193796 'Kdm4b' mRNA 1790.01 1904 1035.01 17.17 17.9 10.55 5.77 8.06 7 15.20666667 6.943333333 690.04 944.04 809.42 1576.34 814.5 0.001233643 -0.948221005 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0005829///cytosol GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific) GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0033169///histone H3-K9 demethylation+++GO:0070544///histone H3-K36 demethylation+++GO:1900113///negative regulation of histone H3-K9 trimethylation 193813 193813 'Mcfd2' mRNA 2328 2491 2282 69.02 73.13 71.81 94.14 91.25 93.93 71.32 93.10666667 3660 3441 3515 2367 3538.666667 1.39E-20 0.568641926 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0019752///carboxylic acid metabolic process+++GO:0060548///negative regulation of cell death 19383 19383 'Raly' mRNA 176.51 191.04 107.76 4.07 4.31 1.68 2.48 4.41 4.47 3.353333333 3.786666667 124.92 159.25 193.57 158.4366667 159.2466667 0.988147042 0.007674258 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0042632///cholesterol homeostasis+++GO:1903506///regulation of nucleic acid-templated transcription" 193838 193838 'Eme2' mRNA 588 591 554 22.8 22.6 22.79 13.26 13.83 13.4 22.73 13.49666667 393 400 384 577.6666667 392.3333333 1.05E-06 -0.569067489 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0048476///Holliday junction resolvase complex GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0031573///intra-S DNA damage checkpoint+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 19384 19384 'Ran' mRNA 3852 3738 3768 94.55 90.35 98.11 152.55 157.72 155.36 94.33666667 155.21 7148 7216 7047 3786 7137 8.66E-54 0.902304409 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++05166///Human T-cell leukemia virus 1 infection GO:0000785///chromatin+++GO:0001673///male germ cell nucleus+++GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0036126///sperm flagellum+++GO:0042470///melanosome+++GO:0042565///RNA nuclear export complex+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0061676///importin-alpha family protein binding+++GO:0070883///pre-miRNA binding GO:0000054///ribosomal subunit export from nucleus+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000070///mitotic sister chromatid segregation+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007286///spermatid development+++GO:0015031///protein transport+++GO:0021766///hippocampus development+++GO:0030036///actin cytoskeleton organization+++GO:0031503///protein-containing complex localization+++GO:0032092///positive regulation of protein binding+++GO:0034613///cellular protein localization+++GO:0034629///cellular protein-containing complex localization+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043393///regulation of protein binding+++GO:0046039///GTP metabolic process+++GO:0051301///cell division+++GO:0061015///snRNA import into nucleus+++GO:0071389///cellular response to mineralocorticoid stimulus+++GO:1902570///protein localization to nucleolus 19385 19385 'Ranbp1' mRNA 1181 1219 1101 92.58 94.65 91.58 137.24 150.31 144.16 92.93666667 143.9033333 2005 2139 2034 1167 2059.333333 1.21E-26 0.809580712 05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0032838///plasma membrane bounded cell projection cytoplasm+++GO:1904115///axon cytoplasm GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity GO:0007051///spindle organization+++GO:0010976///positive regulation of neuron projection development+++GO:0035690///cellular response to drug+++GO:0043547///positive regulation of GTPase activity+++GO:0046604///positive regulation of mitotic centrosome separation+++GO:0046907///intracellular transport+++GO:0050790///regulation of catalytic activity+++GO:0051592///response to calcium ion+++GO:0072750///cellular response to leptomycin B 19386 19386 'Ranbp2' mRNA 780 784 701 4.31 4.26 4.11 4.16 3.68 4.24 4.226666667 4.026666667 866 748 855 755 823 0.326882446 0.113395283 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005642///annulate lamellae+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0042405///nuclear inclusion body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044614///nuclear pore cytoplasmic filaments+++GO:0044615///nuclear pore nuclear basket+++GO:1990723///cytoplasmic periphery of the nuclear pore complex GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061665///SUMO ligase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001975///response to amphetamine+++GO:0006111///regulation of gluconeogenesis+++GO:0006457///protein folding+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0015031///protein transport+++GO:0016925///protein sumoylation+++GO:0033133///positive regulation of glucokinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0046907///intracellular transport+++GO:0051028///mRNA transport+++GO:0051642///centrosome localization 19387 19387 'Rangap1' mRNA 887 970.02 1012 16.48 17.75 19.95 29.11 31.24 28.21 18.06 29.52 1802.58 1887.15 1692 956.34 1793.91 1.07E-21 0.8935117 03013///Nucleocytoplasmic transport "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016235///aggresome+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044614///nuclear pore cytoplasmic filaments+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle+++GO:1904115///axon cytoplasm+++GO:1990723///cytoplasmic periphery of the nuclear pore complex" GO:0003723///RNA binding+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0046826///negative regulation of protein export from nucleus+++GO:0048678///response to axon injury+++GO:0050790///regulation of catalytic activity+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0090630///activation of GTPase activity+++GO:1904117///cellular response to vasopressin 19395 19395 'Rasgrp2' mRNA 79.33 56.93 39.47 3.79 4.1 1.82 5.76 5.7 6.49 3.236666667 5.983333333 80.28 95.68 104.06 58.57666667 93.34 0.042657663 0.679652502 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04611///Platelet activation+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007264///small GTPase mediated signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0071277///cellular response to calcium ion 19400 19400 'Rapsn' mRNA 263 272 227 9.38 9.61 8.65 8.52 9.7 10.39 9.213333333 9.536666667 274 305 322 254 300.3333333 0.180894549 0.233958028 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0099634///postsynaptic specialization membrane GO:0033130///acetylcholine receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0043495///protein membrane anchor+++GO:0046872///metal ion binding "GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0043525///positive regulation of neuron apoptotic process+++GO:1900075///positive regulation of neuromuscular synaptic transmission+++GO:1901626///regulation of postsynaptic membrane organization+++GO:1903540///establishment of protein localization to postsynaptic membrane" 19401 19401 'Rara' mRNA 1084.04 1042.95 748.97 18.74 17.63 13.64 15.47 13.37 13.4 16.67 14.08 1035.97 886 876.98 958.6533333 932.9833333 0.779049753 -0.045482341 04659///Th17 cell differentiation+++04915///Estrogen signaling pathway+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001972///retinoic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0042826///histone deacetylase binding+++GO:0043422///protein kinase B binding+++GO:0043565///sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0046872///metal ion binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0051018///protein kinase A binding+++GO:0051393///alpha-actinin binding+++GO:1901363///heterocyclic compound binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0001843///neural tube closure+++GO:0001889///liver development+++GO:0002068///glandular epithelial cell development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003417///growth plate cartilage development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009755///hormone-mediated signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0017148///negative regulation of translation+++GO:0021766///hippocampus development+++GO:0030154///cell differentiation+++GO:0030850///prostate gland development+++GO:0030852///regulation of granulocyte differentiation+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0031076///embryonic camera-type eye development+++GO:0031641///regulation of myelination+++GO:0032355///response to estradiol+++GO:0032526///response to retinoic acid+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0033189///response to vitamin A+++GO:0034097///response to cytokine+++GO:0035264///multicellular organism growth+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043277///apoptotic cell clearance+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045471///response to ethanol+++GO:0045596///negative regulation of cell differentiation+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045947///negative regulation of translational initiation+++GO:0048167///regulation of synaptic plasticity+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0051099///positive regulation of binding+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060010///Sertoli cell fate commitment+++GO:0060173///limb development+++GO:0060324///face development+++GO:0060348///bone development+++GO:0060534///trachea cartilage development+++GO:0060591///chondroblast differentiation+++GO:0061037///negative regulation of cartilage development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071391///cellular response to estrogen stimulus" 19411 19411 'Rarg' mRNA 1210 1190 945 23.41 22.43 19.44 23.81 22.68 20.97 21.76 22.48666667 1422 1314 1204 1115 1313.333333 0.024963384 0.228054872 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001843///neural tube closure+++GO:0002063///chondrocyte development+++GO:0002068///glandular epithelial cell development+++GO:0003406///retinal pigment epithelium development+++GO:0003417///growth plate cartilage development+++GO:0003430///growth plate cartilage chondrocyte growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009755///hormone-mediated signaling pathway+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031076///embryonic camera-type eye development+++GO:0031641///regulation of myelination+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032526///response to retinoic acid+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043068///positive regulation of programmed cell death+++GO:0045596///negative regulation of cell differentiation+++GO:0045637///regulation of myeloid cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048048///embryonic eye morphogenesis+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048608///reproductive structure development+++GO:0048732///gland development+++GO:0060041///retina development in camera-type eye+++GO:0060173///limb development+++GO:0060324///face development+++GO:0060348///bone development+++GO:0060349///bone morphogenesis+++GO:0060429///epithelium development+++GO:0060534///trachea cartilage development+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0061037///negative regulation of cartilage development+++GO:0070384///Harderian gland development+++GO:0071300///cellular response to retinoic acid+++GO:1990830///cellular response to leukemia inhibitory factor" 194126 194126 'Mtmr11' mRNA 1983 2059 1878 38.92 39.77 39.1 13.49 12.73 13.34 39.26333333 13.18666667 791 729 757 1973.333333 759 3.91E-74 -1.389734676 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0004438///phosphatidylinositol-3-phosphatase activity GO:0046856///phosphatidylinositol dephosphorylation 19414 19414 'Rasa3' mRNA 255 269 279 3.34 3.46 3.87 10.18 10.31 9.87 3.556666667 10.12 895 886 841 267.6666667 874 2.47E-49 1.694075167 04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane GO:0005096///GTPase activator activity+++GO:0015278///calcium-release channel activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0034605///cellular response to heat+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051209///release of sequestered calcium ion into cytosol 19415 19415 'Rasal1' mRNA 37 43 32 0.66 0.76 0.61 1.28 0.97 1.59 0.676666667 1.28 83 63 99 37.33333333 81.66666667 0.001097677 1.120186839 04014///Ras signaling pathway GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005096///GTPase activator activity+++GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 19416 19416 'Rasd1' mRNA 30 21 14 1.09 0.75 0.54 2.91 2.23 1.7 0.793333333 2.28 92 69 52 21.66666667 71 3.82E-05 1.704942369 04713///Circadian entrainment+++04934///Cushing syndrome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0007165///signal transduction+++GO:0007263///nitric oxide mediated signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated" 19417 19417 'Rasgrf1' mRNA 84 98 94 1.83 2.59 2.85 1.44 0.8 1.31 2.423333333 1.183333333 55 24 33 92 37.33333333 1.64E-04 -1.320090904 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04510///Focal adhesion GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0097440///apical dendrite GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031267///small GTPase binding+++GO:0035254///glutamate receptor binding GO:0007264///small GTPase mediated signal transduction+++GO:0008283///cell proliferation+++GO:0031175///neuron projection development+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035020///regulation of Rac protein signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0046578///regulation of Ras protein signal transduction+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048167///regulation of synaptic plasticity+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity+++GO:2000310///regulation of NMDA receptor activity 19418 19418 'Rasgrf2' mRNA 19 17 9 0.12 0.11 0.06 0.09 0.06 0.09 0.096666667 0.08 14 10 15 15 13 0.823550341 -0.208553155 04010///MAPK signaling pathway+++04014///Ras signaling pathway GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005516///calmodulin binding GO:0007264///small GTPase mediated signal transduction+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035023///regulation of Rho protein signal transduction+++GO:0046578///regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0060291///long-term synaptic potentiation+++GO:2000310///regulation of NMDA receptor activity 19419 19419 'Rasgrp1' mRNA 630 650 657 6.57 6.67 7.27 4.07 3.93 4.31 6.836666667 4.103333333 449 424 461 645.6666667 444.6666667 1.75E-06 -0.551250122 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04611///Platelet activation+++04660///T cell receptor signaling pathway+++05200///Pathways in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0019992///diacylglycerol binding+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001816///cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0007264///small GTPase mediated signal transduction+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0030101///natural killer cell activation+++GO:0030154///cell differentiation+++GO:0032252///secretory granule localization+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0035556///intracellular signal transduction+++GO:0042098///T cell proliferation+++GO:0042100///B cell proliferation+++GO:0042110///T cell activation+++GO:0042113///B cell activation+++GO:0043303///mast cell degranulation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046330///positive regulation of JNK cascade+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0050790///regulation of catalytic activity+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090630///activation of GTPase activity 194219 194219 'Slfnl1' mRNA 1 1 1 0.04 0.04 0.05 0 0 0.12 0.043333333 0.04 0 0 4 1 1.333333333 0.894424787 0.408851779 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 194231 194231 'Cnksr1' mRNA 691 703 700 16.88 17.6 18.66 8.62 8.48 9.02 17.71333333 8.706666667 407 391 407 698 401.6666667 3.01E-13 -0.809915462 GO:0005938///cell cortex "GO:0016301///kinase activity+++GO:0030674///protein binding, bridging" GO:0007265///Ras protein signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0016310///phosphorylation 194237 194237 'Rimkla' mRNA 118 111 115 1.56 1.45 1.62 0.41 0.57 0.51 1.543333333 0.496666667 36 48 43 114.6666667 42.33333333 4.55E-07 -1.448447541 "00250///Alanine, aspartate and glutamate metabolism" GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016879///ligase activity, forming carbon-nitrogen bonds+++GO:0046872///metal ion binding+++GO:0072590///N-acetyl-L-aspartate-L-glutamate ligase activity" GO:0006464///cellular protein modification process 194268 194268 '9930104L06Rik' mRNA 466 442 412 8.75 8.17 8.17 5.56 5.3 5.97 8.363333333 5.61 341 317 358 440 338.6666667 0.003954716 -0.388426688 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 19428 19428 'Rasl2-9' mRNA 6 7 1 0.38 0.44 0.07 0.66 0.62 0.23 0.296666667 0.503333333 12 11 4 4.666666667 9 0.426630792 0.955722898 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++05166///Human T-cell leukemia virus 1 infection GO:0000785///chromatin+++GO:0001673///male germ cell nucleus+++GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0036126///sperm flagellum+++GO:0042470///melanosome+++GO:0042565///RNA nuclear export complex+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0061676///importin-alpha family protein binding+++GO:0070883///pre-miRNA binding GO:0000054///ribosomal subunit export from nucleus+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000070///mitotic sister chromatid segregation+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0030036///actin cytoskeleton organization+++GO:0032092///positive regulation of protein binding+++GO:0034613///cellular protein localization+++GO:0034629///cellular protein-containing complex localization+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043393///regulation of protein binding+++GO:0046039///GTP metabolic process+++GO:0051301///cell division+++GO:0061015///snRNA import into nucleus+++GO:1902570///protein localization to nucleolus 194309 194309 'Vps37d' mRNA 53 48 10 2 1.8 0.4 0.2 0.38 0.51 1.4 0.363333333 5 10 15 37 10 0.006416461 -1.868868754 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006612///protein targeting to membrane+++GO:0006623///protein targeting to vacuole+++GO:0015031///protein transport+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 19434 19434 'Rax' mRNA 1 0 0 0.03 0 0 0.03 0 0 0.01 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007420///brain development+++GO:0021854///hypothalamus development+++GO:0043010///camera-type eye development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060173///limb development" 194388 194388 'Tet3' mRNA 1367 1289 1019 6.42 5.96 5.07 5.38 4.52 5.17 5.816666667 5.023333333 1326 1094 1246 1225 1222 0.932047067 -0.011781225 GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0070579///methylcytosine dioxygenase activity GO:0006211///5-methylcytosine catabolic process+++GO:0006325///chromatin organization+++GO:0006493///protein O-linked glycosylation+++GO:0007275///multicellular organism development+++GO:0035511///oxidative DNA demethylation+++GO:0044727///DNA demethylation of male pronucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070989///oxidative demethylation+++GO:0080111///DNA demethylation+++GO:0080182///histone H3-K4 trimethylation 194401 194401 'Mical3' mRNA 1303 1216 1196 6.94 6.29 6.74 4.25 3.63 4.27 6.656666667 4.05 894 733 859 1238.333333 828.6666667 4.69E-10 -0.592493334 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body "GO:0003779///actin binding+++GO:0004497///monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0031267///small GTPase binding+++GO:0043914///NADPH:sulfur oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0071949///FAD binding" GO:0006887///exocytosis+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0010735///positive regulation of transcription via serum response element binding+++GO:0030042///actin filament depolymerization+++GO:0051301///cell division 194590 194590 'Reps2' mRNA 231 247 175 1.63 1.7 1.3 3.8 3.55 3.59 1.543333333 3.646666667 622 566 569 217.6666667 585.6666667 2.08E-25 1.420644861 GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0016197///endosomal transport 194655 194655 'Klf11' mRNA 217 241 268 2.94 3.21 3.85 2.69 2.71 3.19 3.333333333 2.863333333 228 225 262 242 238.3333333 0.869607221 -0.037336829 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0030097///hemopoiesis+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901653///cellular response to peptide" 194744 194744 'Slc25a43' mRNA 26 31 32 1.06 1.37 1.6 4.21 3.89 3.82 1.343333333 3.973333333 104 94 96 29.66666667 98 7.59E-08 1.709783643 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0055085///transmembrane transport 194856 194856 'Rhox4e' mRNA 0 2.21 3.22 0 0.14 0.32 0.07 0.1 0 0.153333333 0.056666667 1.19 1.13 0 1.81 0.773333333 0.661296467 -1.3596674 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0008150///biological_process 194908 194908 'Pld6' mRNA 83 79 87 2.7 2.54 3.01 0.99 0.96 1.08 2.75 1.01 35 33 37 83 35 1.13E-04 -1.260078939 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004630///phospholipase D activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0035755///cardiolipin hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008053///mitochondrial fusion+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0016042///lipid catabolic process+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 194952 194952 'Jmjd4' mRNA 452.57 393.23 408.63 4.43 3.87 4.23 4.71 4.56 4.6 4.176666667 4.623333333 518.97 493.47 502.53 418.1433333 504.99 0.049211391 0.25971263 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0033749///histone demethylase activity (H4-R3 specific)+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0010629///negative regulation of gene expression+++GO:0018126///protein hydroxylation+++GO:0043985///histone H4-R3 methylation+++GO:0045905///positive regulation of translational termination 194974 194974 'Sun3' mRNA 55.52 43.95 41.46 0.64 0.47 0.48 0.44 0.37 0.39 0.53 0.4 46.43 32.61 39.86 46.97666667 39.63333333 0.585899306 -0.260638607 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex GO:0005515///protein binding+++GO:0043495///protein membrane anchor GO:0006998///nuclear envelope organization 195018 195018 'Zzef1' mRNA 896 872 839 5.02 4.83 5.16 4.97 4.38 5.06 5.003333333 4.803333333 964 865 996 869 941.6666667 0.351936314 0.103901561 GO:0005575///cellular_component+++GO:0009986///cell surface+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0098794///postsynapse GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061659///ubiquitin-like protein ligase activity "GO:0007405///neuroblast proliferation+++GO:0008150///biological_process+++GO:0008542///visual learning+++GO:0016567///protein ubiquitination+++GO:0035249///synaptic transmission, glutamatergic+++GO:0048167///regulation of synaptic plasticity+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation" 195040 195040 'Tmem199' mRNA 851 805 841 38.12 35.59 39.97 37.53 37.15 38.04 37.89333333 37.57333333 962 929 943 832.3333333 944.6666667 0.102393596 0.169548636 GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function GO:0006879///cellular iron ion homeostasis+++GO:0007042///lysosomal lumen acidification+++GO:0036295///cellular response to increased oxygen levels+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:1905146///lysosomal protein catabolic process 195046 195046 'Nlrp1a' mRNA 6.82 4.71 3.1 0.08 0.05 0.04 0.22 0.43 0.32 0.056666667 0.323333333 23.03 44.03 31.96 4.876666667 33.00666667 2.25E-05 2.912899454 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0061702///inflammasome complex+++GO:0072558///NLRP1 inflammasome complex GO:0000166///nucleotide binding+++GO:0003690///double-stranded DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0043621///protein self-association+++GO:0097110///scaffold protein binding GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0012501///programmed cell death+++GO:0032495///response to muramyl dipeptide+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0042742///defense response to bacterium+++GO:0042981///regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051260///protein homooligomerization+++GO:0051402///neuron apoptotic process+++GO:0051607///defense response to virus+++GO:0070269///pyroptosis+++GO:0097264///self proteolysis+++GO:0097300///programmed necrotic cell death+++GO:1904784///NLRP1 inflammasome complex assembly 195208 195208 'Dcdc2a' mRNA 82 74 78 1.02 0.98 1.31 0.29 0.17 0.45 1.103333333 0.303333333 16 11 27 78 18 1.16E-07 -2.128846151 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0034451///centriolar satellite+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0060091///kinocilium+++GO:0072686///mitotic spindle GO:0003674///molecular_function+++GO:0019894///kinesin binding "GO:0001764///neuron migration+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0008542///visual learning+++GO:0019228///neuronal action potential+++GO:0030030///cell projection organization+++GO:0030111///regulation of Wnt signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035556///intracellular signal transduction+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048813///dendrite morphogenesis+++GO:0060271///cilium assembly+++GO:1902017///regulation of cilium assembly" 195209 195209 'Zfp469' mRNA 253 301 234 0.9 0.96 0.76 0.7 0.6 0.61 0.873333333 0.636666667 236 195 196 262.6666667 209 0.063229347 -0.339671596 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 195434 195434 'Utp14b' mRNA 401.32 364.16 184.21 5.89 5.26 2.87 2.32 3.71 3.45 4.673333333 3.16 182.12 284.25 262.18 316.5633333 242.85 0.157129821 -0.37556349 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032040///small-subunit processome GO:0006364///rRNA processing+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0042254///ribosome biogenesis+++GO:0051321///meiotic cell cycle 195522 195522 'Zfp691' mRNA 374 375 388 12.03 12.23 13.67 8.29 8.84 9.53 12.64333333 8.886666667 288 306 313 379 302.3333333 0.023013191 -0.338569693 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 195531 195531 'Zfp982' mRNA 311 342 268 3.98 4.34 3.61 1.9 1.87 1.83 3.976666667 1.866666667 170.11 166 166 307 167.37 7.25E-08 -0.883605939 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 195646 195646 'Hs3st2' mRNA 177.68 188.78 123.91 4.31 4.25 3.36 0.21 0.09 0.34 3.973333333 0.213333333 12.08 3 14.16 163.4566667 9.746666667 4.17E-26 -4.078887592 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0033871///[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity GO:0007623///circadian rhythm 195726 195726 'Scml1' mRNA 2 2 1 0.05 0.06 0.03 0.19 0 0.03 0.046666667 0.073333333 7 0 1 1.666666667 2.666666667 0.790763472 0.654060944 195727 195727 'Nhs' mRNA 465 410 353 2.89 2.65 2.12 1.39 1.39 1.6 2.553333333 1.46 274 250 290 409.3333333 271.3333333 4.94E-05 -0.601853937 GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0030054///cell junction GO:0002088///lens development in camera-type eye+++GO:0030154///cell differentiation 195733 195733 'Grhl1' mRNA 415 422 416 6.53 6.56 6.93 4.24 4.15 4.11 6.673333333 4.166666667 310 298 292 417.6666667 300 3.18E-04 -0.489895397 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002934///desmosome organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008544///epidermis development+++GO:0045616///regulation of keratinocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061436///establishment of skin barrier" 19645 19645 'Rb1' mRNA 853 924 570 9.89 10.46 6.96 4.5 5.3 5.99 9.103333333 5.263333333 450 518 580 782.3333333 516 8.29E-05 -0.600897457 01522///Endocrine resistance+++04110///Cell cycle+++04218///Cellular senescence+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005819///spindle+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0016605///PML body+++GO:0035189///Rb-E2F complex GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061676///importin-alpha family protein binding+++GO:0097718///disordered domain specific binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0001894///tissue homeostasis+++GO:0002062///chondrocyte differentiation+++GO:0003180///aortic valve morphogenesis+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007265///Ras protein signal transduction+++GO:0007346///regulation of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030308///negative regulation of cell growth+++GO:0031134///sister chromatid biorientation+++GO:0031175///neuron projection development+++GO:0032869///cellular response to insulin stimulus+++GO:0034088///maintenance of mitotic sister chromatid cohesion+++GO:0034349///glial cell apoptotic process+++GO:0035914///skeletal muscle cell differentiation+++GO:0042551///neuron maturation+++GO:0043353///enucleate erythrocyte differentiation+++GO:0043550///regulation of lipid kinase activity+++GO:0045445///myoblast differentiation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048565///digestive tract development+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0051146///striated muscle cell differentiation+++GO:0051301///cell division+++GO:0051402///neuron apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0071922///regulation of cohesin loading+++GO:0071930///negative regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0097284///hepatocyte apoptotic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1902948///negative regulation of tau-protein kinase activity+++GO:1903055///positive regulation of extracellular matrix organization+++GO:1903944///negative regulation of hepatocyte apoptotic process+++GO:1904028///positive regulation of collagen fibril organization+++GO:1904761///negative regulation of myofibroblast differentiation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2001234///negative regulation of apoptotic signaling pathway" 19646 19646 'Rbbp4' mRNA 5101.92 4982.97 4656.98 62.19 59.74 60.22 53.56 55.81 55.41 60.71666667 54.92666667 5057.83 5148.69 5068.35 4913.956667 5091.623333 0.570655549 0.040849046 04218///Cellular senescence GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016581///NuRD complex+++GO:0016589///NURF complex+++GO:0032991///protein-containing complex+++GO:0033186///CAF-1 complex+++GO:0035098///ESC/E(Z) complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0031497///chromatin assembly+++GO:0031507///heterochromatin assembly+++GO:0060416///response to growth hormone 19647 19647 'Rbbp6' mRNA 998 999 872 10.71 10.98 10.13 9.49 7.68 8.54 10.60666667 8.57 1051 849 920 956.3333333 940 0.790482439 -0.036109667 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0003676///nucleic acid binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001701///in utero embryonic development+++GO:0006260///DNA replication+++GO:0006275///regulation of DNA replication+++GO:0006397///mRNA processing+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0035264///multicellular organism growth+++GO:0048568///embryonic organ development+++GO:0061053///somite development 19649 19649 'Robo3' mRNA 1 4 0 0.02 0.07 0 0.03 0.23 0.07 0.03 0.11 2 15 4 1.666666667 7 0.179685242 2.102023325 04360///Axon guidance GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0005515///protein binding GO:0001764///neuron migration+++GO:0006935///chemotaxis+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0016199///axon midline choice point recognition+++GO:0030154///cell differentiation+++GO:0061642///chemoattraction of axon+++GO:0061643///chemorepulsion of axon+++GO:0071679///commissural neuron axon guidance 19650 19650 'Rbl1' mRNA 149 165 122 2.37 2.5 1.62 4.1 5.7 4.84 2.163333333 4.88 358 444 414 145.3333333 405.3333333 1.36E-18 1.474390511 04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0043550///regulation of lipid kinase activity+++GO:0051302///regulation of cell division+++GO:0051726///regulation of cell cycle+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000773///negative regulation of cellular senescence 19651 19651 'Rbl2' mRNA 1503.49 1687 1607.73 16.32 18.02 18.51 12.49 12.77 12.32 17.61666667 12.52666667 1323.66 1323.35 1266.05 1599.406667 1304.353333 3.51E-04 -0.306577983 04068///FoxO signaling pathway+++04110///Cell cycle+++04151///PI3K-Akt signaling pathway+++04218///Cellular senescence+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990841///promoter-specific chromatin binding GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0043550///regulation of lipid kinase activity+++GO:0051302///regulation of cell division+++GO:0051726///regulation of cell cycle+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 19652 19652 'Rbm3' mRNA 2589.91 2660.63 2704.3 110.56 111.75 123.61 167.73 154.9 161.1 115.3066667 161.2433333 4422.67 3994.57 4103.03 2651.613333 4173.423333 1.55E-21 0.640442048 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0015934///large ribosomal subunit+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0043023///ribosomal large subunit binding "GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0009409///response to cold+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0045727///positive regulation of translation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 19653 19653 'Rbm4' mRNA 545.7 500.83 479.58 12.33 10.95 11.22 13.85 12.36 12.73 11.5 12.98 710.07 619.39 629.97 508.7033333 653.1433333 0.002495549 0.349567714 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008270///zinc ion binding+++GO:0030332///cyclin binding+++GO:0035198///miRNA binding+++GO:0036002///pre-mRNA binding+++GO:0046872///metal ion binding+++GO:0097157///pre-mRNA intronic binding+++GO:0097158///pre-mRNA intronic pyrimidine-rich binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0002190///cap-independent translational initiation+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0031016///pancreas development+++GO:0031047///gene silencing by RNA+++GO:0032055///negative regulation of translation in response to stress+++GO:0032922///circadian regulation of gene expression+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0035883///enteroendocrine cell differentiation+++GO:0042593///glucose homeostasis+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045727///positive regulation of translation+++GO:0045947///negative regulation of translational initiation+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046685///response to arsenic-containing substance+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0097167///circadian regulation of translation" 19654 19654 'Rbm6' mRNA 1157 1203 1192 17.66 17.51 18.66 15.43 14.91 15.39 17.94333333 15.24333333 1185 1144 1183 1184 1170.666667 0.809491281 -0.029062284 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0008150///biological_process" 19655 19655 'Rbmx' mRNA 1947 1883 1854.93 42.14 40.34 41.75 28.94 28.88 27.38 41.41 28.4 1579 1481.98 1425 1894.976667 1495.326667 3.16E-06 -0.354281981 03040///Spliceosome GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0032991///protein-containing complex+++GO:0044530///supraspliceosomal complex+++GO:0070062///extracellular exosome+++GO:0071013///catalytic step 2 spliceosome GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006366///transcription by RNA polymerase II+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0008380///RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0071347///cellular response to interleukin-1" 19656 19656 'Rbmxl1' mRNA 860 876 772.07 29.02 29.17 27.96 34.69 35.22 34.05 28.71666667 34.65333333 1176 1158.02 1110 836.0233333 1148.006667 3.00E-07 0.44754656 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0032991///protein-containing complex+++GO:0044530///supraspliceosomal complex+++GO:0070062///extracellular exosome+++GO:0071013///catalytic step 2 spliceosome GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006366///transcription by RNA polymerase II+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0008380///RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0051260///protein homooligomerization+++GO:0071347///cellular response to interleukin-1" 19657 19657 'Rbmy' mRNA 0 0 0.11 0 0 0 0 0 0.01 0 0.003333333 0 0 0.29 0.036666667 0.096666667 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 19659 19659 'Rbp1' mRNA 6241 5918 6066 131.76 122.99 135.85 247.27 264.09 242.94 130.2 251.4333333 13473 14052 12816 6075 13447 1.29E-75 1.133902453 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0044297///cell body GO:0005501///retinoid binding+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:1904768///all-trans-retinol binding GO:0002138///retinoic acid biosynthetic process+++GO:0006776///vitamin A metabolic process+++GO:0015908///fatty acid transport+++GO:0030852///regulation of granulocyte differentiation+++GO:0033189///response to vitamin A+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0055088///lipid homeostasis 19660 19660 'Rbp2' mRNA 0 1 1 0 0.11 0.11 0.09 0.1 0 0.073333333 0.063333333 1 1 0 0.666666667 0.666666667 0.998591786 -0.025867048 04977///Vitamin digestion and absorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005501///retinoid binding+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding GO:0001523///retinoid metabolic process+++GO:0015908///fatty acid transport 19662 19662 'Rbp4' mRNA 3594 3905 3534 246.38 265.01 257.26 606.74 638.88 610.67 256.2166667 618.7633333 9986 10242 9715 3677.666667 9981 3.08E-142 1.429794806 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex GO:0005501///retinoid binding+++GO:0005515///protein binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:0034632///retinol transmembrane transporter activity+++GO:0044877///protein-containing complex binding GO:0001654///eye development+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006094///gluconeogenesis+++GO:0007283///spermatogenesis+++GO:0007507///heart development+++GO:0008584///male gonad development+++GO:0009790///embryo development+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030324///lung development+++GO:0032024///positive regulation of insulin secretion+++GO:0032526///response to retinoic acid+++GO:0032868///response to insulin+++GO:0034633///retinol transport+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:0042593///glucose homeostasis+++GO:0045471///response to ethanol+++GO:0048562///embryonic organ morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048738///cardiac muscle tissue development+++GO:0048807///female genitalia morphogenesis+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060041///retina development in camera-type eye+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0060065///uterus development+++GO:0060068///vagina development+++GO:0060157///urinary bladder development+++GO:0060347///heart trabecula formation+++GO:0071939///vitamin A import 19663 19663 'Rbpms' mRNA 953 1020 371 31.67 34.16 10.92 10.8 18.81 20.85 25.58333333 16.82 416 685 737 781.3333333 612.6666667 0.597605073 -0.336482397 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008143///poly(A) binding+++GO:0042803///protein homodimerization activity "GO:0006979///response to oxidative stress+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060391///positive regulation of SMAD protein signal transduction" 19664 19664 'Rbpj' mRNA 1177.08 1197.98 1084.16 10.29 10.3 10.2 16.14 15.15 15.73 10.26333333 15.67333333 2222.96 1954.13 2025.15 1153.073333 2067.413333 4.35E-29 0.831064068 04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05017///Spinocerebellar ataxia+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0047485///protein N-terminus binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001756///somitogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001947///heart looping+++GO:0001974///blood vessel remodeling+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0003139///secondary heart field specification+++GO:0003151///outflow tract morphogenesis+++GO:0003157///endocardium development+++GO:0003160///endocardium morphogenesis+++GO:0003176///aortic valve development+++GO:0003177///pulmonary valve development+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003256///regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0007219///Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009912///auditory receptor cell fate commitment+++GO:0009957///epidermal cell fate specification+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0021983///pituitary gland development+++GO:0030097///hemopoiesis+++GO:0030182///neuron differentiation+++GO:0030183///B cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030279///negative regulation of ossification+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032633///interleukin-4 production+++GO:0035019///somatic stem cell population maintenance+++GO:0035481///positive regulation of Notch signaling pathway involved in heart induction+++GO:0035912///dorsal aorta morphogenesis+++GO:0036302///atrioventricular canal development+++GO:0042127///regulation of cell proliferation+++GO:0042742///defense response to bacterium+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048505///regulation of timing of cell differentiation+++GO:0048733///sebaceous gland development+++GO:0048820///hair follicle maturation+++GO:0048844///artery morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060412///ventricular septum morphogenesis+++GO:0060486///Clara cell differentiation+++GO:0060716///labyrinthine layer blood vessel development+++GO:0060844///arterial endothelial cell fate commitment+++GO:0060853///Notch signaling pathway involved in arterial endothelial cell fate commitment+++GO:0061344///regulation of cell adhesion involved in heart morphogenesis+++GO:0061371///determination of heart left/right asymmetry+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0072554///blood vessel lumenization+++GO:0097101///blood vessel endothelial cell fate specification+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1901186///positive regulation of ERBB signaling pathway+++GO:1901189///positive regulation of ephrin receptor signaling pathway+++GO:1901297///positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis" 19668 19668 'Rbpjl' mRNA 59 42 51 2.47 1.72 2.14 1.37 1.56 1.05 2.11 1.326666667 39 40 30 50.66666667 36.33333333 0.250263496 -0.493461103 04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05017///Spinocerebellar ataxia+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 19671 19671 'Rce1' mRNA 754 752 728 32.38 32.16 33.42 34.1 31.47 31.34 32.65333333 32.30333333 910 816 797 744.6666667 841 0.131942545 0.162860811 00900///Terpenoid backbone biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008238///exopeptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0018342///protein prenylation+++GO:0071586///CAAX-box protein processing 19672 19672 'Rcn1' mRNA 14073 14845 12780 252.01 261.6 242.77 108.37 109.12 108.87 252.1266667 108.7866667 6963 6848 6774 13899.33333 6861.666667 3.06E-96 -1.027858406 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0043010///camera-type eye development 19674 19674 'Rcvrn' mRNA 1 0 0 0.06 0 0 0.05 0 0.05 0.02 0.033333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873439817 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0050896///response to stimulus+++GO:0051924///regulation of calcium ion transport 19679 19679 'Pitpnm2' mRNA 267 210 192 2.03 1.61 1.57 1.33 1.32 1.58 1.736666667 1.41 202 198 227 223 209 0.673646829 -0.101962865 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0044297///cell body GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005548///phospholipid transporter activity+++GO:0008289///lipid binding+++GO:0008525///phosphatidylcholine transporter activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0015914///phospholipid transport+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0120009///intermembrane lipid transfer 19682 19682 'Rdh5' mRNA 580 589 628 25.62 25.12 28.36 17.86 17.01 18.14 26.36666667 17.67 460 429 460 599 449.6666667 4.71E-04 -0.428113853 00830///Retinol metabolism GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044297///cell body "GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0007601///visual perception+++GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0050896///response to stimulus 19683 19683 'Rdh16' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00830///Retinol metabolism GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0047023///androsterone dehydrogenase activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:1900054///positive regulation of retinoic acid biosynthetic process 19684 19684 'Rdx' mRNA 2301 2268 2250 37.34 34.4 37.22 33.09 34.26 33.7 36.32 33.68333333 2414 2377 2352 2273 2381 0.518549226 0.054690549 04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030315///T-tubule+++GO:0030496///midbody+++GO:0030864///cortical actin cytoskeleton+++GO:0032154///cleavage furrow+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045177///apical part of cell+++GO:0051286///cell tip+++GO:0071944///cell periphery GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding+++GO:0050839///cell adhesion molecule binding+++GO:0051117///ATPase binding GO:0008360///regulation of cell shape+++GO:0008361///regulation of cell size+++GO:0010628///positive regulation of gene expression+++GO:0030033///microvillus assembly+++GO:0030335///positive regulation of cell migration+++GO:0032231///regulation of actin filament bundle assembly+++GO:0034111///negative regulation of homotypic cell-cell adhesion+++GO:0034260///negative regulation of GTPase activity+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0043087///regulation of GTPase activity+++GO:0045176///apical protein localization+++GO:0045184///establishment of protein localization+++GO:0045792///negative regulation of cell size+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping+++GO:0061028///establishment of endothelial barrier+++GO:0072659///protein localization to plasma membrane+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:1900027///regulation of ruffle assembly+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1902115///regulation of organelle assembly+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1903392///negative regulation of adherens junction organization+++GO:2000643///positive regulation of early endosome to late endosome transport 19687 19687 'Rfc1' mRNA 993.47 1068.67 1103.97 10.94 11.48 12.82 10.53 10.65 10.15 11.74666667 10.44333333 1117.69 1124.86 1035.05 1055.37 1092.533333 0.787532877 0.036310655 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005663///DNA replication factor C complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031391///Elg1 RFC-like complex+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0003690///double-stranded DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:0061860///DNA clamp unloader activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090618///DNA clamp unloading" 19691 19691 'Recql' mRNA 345.77 462.78 430.09 4.83 6.22 6.1 4.56 5.21 4.27 5.716666667 4.68 379.83 415.14 335.55 412.88 376.84 0.439645892 -0.144345453 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0036310///annealing helicase activity+++GO:0043138///3'-5' DNA helicase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0000733///DNA strand renaturation+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0032508///DNA duplex unwinding 19694 19694 'Reg3a' mRNA 17 11 13 1.36 0.87 1.11 0.14 0.07 0 1.113333333 0.07 2 1 0 13.66666667 1 0.002257611 -3.789045499 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0070492///oligosaccharide binding GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0043434///response to peptide hormone+++GO:0044278///cell wall disruption in other organism+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090303///positive regulation of wound healing 19695 19695 'Reg3g' mRNA 75 56 57 6.69 4.95 5.39 408.32 424.84 421.46 5.676666667 418.2066667 5241 5309 5222 62.66666667 5257.333333 0 6.380231378 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0030141///secretory granule+++GO:0062023///collagen-containing extracellular matrix GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042834///peptidoglycan binding+++GO:0070492///oligosaccharide binding GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0043434///response to peptide hormone+++GO:0044278///cell wall disruption in other organism+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051838///cytolysis by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090303///positive regulation of wound healing 19696 19696 'Rel' mRNA 88 71 67 0.62 0.49 0.5 2.43 2 2.53 0.536666667 2.32 396 318 400 75.33333333 371.3333333 4.16E-34 2.290088011 04014///Ras signaling pathway+++04624///Toll and Imd signaling pathway+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0001816///cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010629///negative regulation of gene expression+++GO:0032688///negative regulation of interferon-beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0033554///cellular response to stress+++GO:0034097///response to cytokine+++GO:0038061///NIK/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901215///negative regulation of neuron death" 19697 19697 'Rela' mRNA 2459 2560 2027 51.61 52.57 45.24 41.89 52.39 49.66 49.80666667 47.98 2299 2799 2634 2348.666667 2577.333333 0.21892113 0.128753262 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04071///Sphingolipid signaling pathway+++04137///Mitophagy - animal+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05030///Cocaine addiction+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05212///Pancreatic cancer+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0035525///NF-kappaB p50/p65 complex+++GO:0045202///synapse+++GO:0071159///NF-kappaB complex+++GO:0098978///glutamatergic synapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0042277///peptide binding+++GO:0042301///phosphate ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042805///actinin binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0051059///NF-kappaB binding+++GO:0071532///ankyrin repeat binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001889///liver development+++GO:0001942///hair follicle development+++GO:0006117///acetaldehyde metabolic process+++GO:0006325///chromatin organization+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0009887///animal organ morphogenesis+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0010224///response to UV-B+++GO:0014040///positive regulation of Schwann cell differentiation+++GO:0014070///response to organic cyclic compound+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032868///response to insulin+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0033234///negative regulation of protein sumoylation+++GO:0033554///cellular response to stress+++GO:0033590///response to cobalamin+++GO:0034097///response to cytokine+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0035994///response to muscle stretch+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042177///negative regulation of protein catabolic process+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043200///response to amino acid+++GO:0043278///response to morphine+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050727///regulation of inflammatory response+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051591///response to cAMP+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1+++GO:0071216///cellular response to biotic stimulus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071224///cellular response to peptidoglycan+++GO:0071316///cellular response to nicotine+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904385///cellular response to angiotensin+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:2000630///positive regulation of miRNA metabolic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 19698 19698 'Relb' mRNA 437.63 459.09 505.66 9.24 9.4 11.25 17.18 16.72 17.61 9.963333333 17.17 851.77 822.2 857.43 467.46 843.8 1.36E-13 0.83781109 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010628///positive regulation of gene expression+++GO:0019882///antigen processing and presentation+++GO:0030098///lymphocyte differentiation+++GO:0032688///negative regulation of interferon-beta production+++GO:0032922///circadian regulation of gene expression+++GO:0033554///cellular response to stress+++GO:0034097///response to cytokine+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042088///T-helper 1 type immune response+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045063///T-helper 1 cell differentiation+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0071470///cellular response to osmotic stress" 19699 19699 'Reln' mRNA 1060 1196 949 4.73 5.24 4.49 1.45 1.41 1.61 4.82 1.49 373 356 403 1068.333333 377.3333333 1.84E-45 -1.509734271 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05017///Spinocerebellar ataxia+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0062023///collagen-containing extracellular matrix GO:0000150///recombinase activity+++GO:0003677///DNA binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070325///lipoprotein particle receptor binding+++GO:0070326///very-low-density lipoprotein particle receptor binding "GO:0000904///cell morphogenesis involved in differentiation+++GO:0001764///neuron migration+++GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0010001///glial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021511///spinal cord patterning+++GO:0021517///ventral spinal cord development+++GO:0021542///dentate gyrus development+++GO:0021766///hippocampus development+++GO:0021800///cerebral cortex tangential migration+++GO:0021819///layer formation in cerebral cortex+++GO:0021987///cerebral cortex development+++GO:0030900///forebrain development+++GO:0032008///positive regulation of TOR signaling+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0035418///protein localization to synapse+++GO:0038026///reelin-mediated signaling pathway+++GO:0042403///thyroid hormone metabolic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0048265///response to pain+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050795///regulation of behavior+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0090129///positive regulation of synapse maturation+++GO:0097107///postsynaptic density assembly+++GO:0097114///NMDA glutamate receptor clustering+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0097120///receptor localization to synapse+++GO:0097477///lateral motor column neuron migration+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1902078///positive regulation of lateral motor column neuron migration+++GO:2000310///regulation of NMDA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000969///positive regulation of AMPA receptor activity" 19700 19700 'Rem1' mRNA 208 190 204 7.59 6.84 7.9 2.29 2.41 1.31 7.443333333 2.003333333 72 74 40 200.6666667 62 8.53E-12 -1.708529716 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:1901842///negative regulation of high voltage-gated calcium channel activity 19701 19701 'Ren1' mRNA 6 1 2 0.25 0.04 0.09 0 0.15 0 0.126666667 0.05 0 4 0 3 1.333333333 0.63284907 -1.157193478 04614///Renin-angiotensin system+++04924///Renin secretion+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0045177///apical part of cell GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0002003///angiotensin maturation+++GO:0002016///regulation of blood volume by renin-angiotensin+++GO:0002018///renin-angiotensin regulation of aldosterone production+++GO:0006508///proteolysis+++GO:0008065///establishment of blood-nerve barrier+++GO:0008217///regulation of blood pressure+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0009755///hormone-mediated signaling pathway+++GO:0010033///response to organic substance+++GO:0032496///response to lipopolysaccharide+++GO:0035690///cellular response to drug+++GO:0035902///response to immobilization stress+++GO:0042493///response to drug+++GO:0042756///drinking behavior+++GO:0043408///regulation of MAPK cascade+++GO:0048469///cell maturation+++GO:0050435///amyloid-beta metabolic process+++GO:0051591///response to cAMP+++GO:0070305///response to cGMP 19703 19703 'Renbp' mRNA 674 746 675 28.54 31.1 30.25 82.57 88.31 82.59 29.96333333 84.49 2243 2337 2174 698.3333333 2251.333333 7.71E-96 1.678231055 00520///Amino sugar and nucleotide sugar metabolism GO:0004857///enzyme inhibitor activity+++GO:0005524///ATP binding+++GO:0016853///isomerase activity+++GO:0017076///purine nucleotide binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0050121///N-acylglucosamine 2-epimerase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006051///N-acetylmannosamine metabolic process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0043086///negative regulation of catalytic activity 19704 19704 'Upf1' mRNA 255 213 211 2.95 2.4 2.59 3.21 2.49 3.13 2.646666667 2.943333333 321 243 302 226.3333333 288.6666667 0.063888445 0.338234844 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0044530///supraspliceosomal complex+++GO:0048471///perinuclear region of cytoplasm" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042162///telomeric DNA binding+++GO:0046872///metal ion binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000294///nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006449///regulation of translational termination+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0032204///regulation of telomere maintenance+++GO:0044770///cell cycle phase transition+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0071044///histone mRNA catabolic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1" 19707 19707 'Reps1' mRNA 278 267 276 5.12 5 5.65 5.25 5.1 4.5 5.256666667 4.95 328 303 262 273.6666667 297.6666667 0.588005822 0.107616652 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0016197///endosomal transport 19708 19708 'Dpf2' mRNA 1894 2078 1835 31.15 33.65 32.02 30.56 30.68 29.54 32.27333333 30.26 2137 2095 2001 1935.666667 2077.666667 0.26528707 0.091536622 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071565///nBAF complex GO:0003712///transcription coregulator activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0062072///H3K9me3 modified histone binding+++GO:0070577///lysine-acetylated histone binding "GO:0006325///chromatin organization+++GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1905454///negative regulation of myeloid progenitor cell differentiation" 19711 19711 'Resp18' mRNA 13 10 14 1.21 0.92 1.38 0.08 0.08 0 1.17 0.053333333 1 1 0 12.33333333 0.666666667 0.002901375 -4.228457877 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0043204///perikaryon+++GO:0048237///rough endoplasmic reticulum lumen GO:0003674///molecular_function GO:0001701///in utero embryonic development 19712 19712 'Rest' mRNA 1171 1196 787 21.54 23.01 13.24 11.3 16.27 16.61 19.26333333 14.72666667 959 1114 1157 1051.333333 1076.666667 0.863090843 0.032922277 04550///Signaling pathways regulating pluripotency of stem cells+++05016///Huntington disease GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001666///response to hypoxia+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002931///response to ischemia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0032348///negative regulation of aldosterone biosynthetic process+++GO:0033554///cellular response to stress+++GO:0035019///somatic stem cell population maintenance+++GO:0035690///cellular response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043922///negative regulation by host of viral transcription+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0046676///negative regulation of insulin secretion+++GO:0050768///negative regulation of neurogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060379///cardiac muscle cell myoblast differentiation+++GO:0070933///histone H4 deacetylation+++GO:0071257///cellular response to electrical stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0097150///neuronal stem cell population maintenance+++GO:0099563///modification of synaptic structure+++GO:1902459///positive regulation of stem cell population maintenance+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903203///regulation of oxidative stress-induced neuron death+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:2000065///negative regulation of cortisol biosynthetic process+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2000706///negative regulation of dense core granule biogenesis+++GO:2000740///negative regulation of mesenchymal stem cell differentiation+++GO:2000798///negative regulation of amniotic stem cell differentiation" 19713 19713 'Ret' mRNA 48 36 33 0.36 0.27 0.25 0.79 0.81 0.88 0.293333333 0.826666667 127 127 133 39 129 9.39E-10 1.717128388 04020///Calcium signaling pathway+++05200///Pathways in cancer+++05216///Thyroid cancer+++05223///Non-small cell lung cancer+++05230///Central carbon metabolism in cancer GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0098797///plasma membrane protein complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001657///ureteric bud development+++GO:0001755///neural crest cell migration+++GO:0001838///embryonic epithelial tube formation+++GO:0006468///protein phosphorylation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007158///neuron cell-cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009653///anatomical structure morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0014042///positive regulation of neuron maturation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030155///regulation of cell adhesion+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0033139///regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0033619///membrane protein proteolysis+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0033674///positive regulation of kinase activity+++GO:0035799///ureter maturation+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0042493///response to drug+++GO:0042551///neuron maturation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045793///positive regulation of cell size+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048265///response to pain+++GO:0048484///enteric nervous system development+++GO:0050770///regulation of axonogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060041///retina development in camera-type eye+++GO:0060384///innervation+++GO:0061146///Peyer's patch morphogenesis+++GO:0071300///cellular response to retinoic acid+++GO:0072300///positive regulation of metanephric glomerulus development+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand" 19714 19714 'Rev3l' mRNA 1173 1291 1019 5.68 6.16 5.24 2.67 2.17 2.42 5.693333333 2.42 630 500 556 1161 562 3.36E-24 -1.056379057 01524///Platinum drug resistance+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016035///zeta DNA polymerase complex "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019985///translesion synthesis+++GO:0042276///error-prone translesion synthesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 19716 19716 'Bex1' mRNA 1253.45 1220.76 1288.6 96.2 92.78 104.94 40.01 41.39 42.82 97.97333333 41.40666667 597.03 601.65 617.2 1254.27 605.2933333 5.01E-29 -1.064568473 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0043014///alpha-tubulin binding GO:0002052///positive regulation of neuroblast proliferation+++GO:0007059///chromosome segregation+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0031103///axon regeneration+++GO:0042127///regulation of cell proliferation+++GO:0045665///negative regulation of neuron differentiation+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0061564///axon development+++GO:1904428///negative regulation of tubulin deacetylation 19718 19718 'Rfc2' mRNA 1038 964 957 40.33 36.94 39.45 44.75 41.32 43.18 38.90666667 43.08333333 1323 1192 1235 986.3333333 1250 1.88E-04 0.329312272 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005663///DNA replication factor C complex+++GO:0031390///Ctf18 RFC-like complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0032508///DNA duplex unwinding+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 19719 19719 'Rfng' mRNA 1618 1683 1505 43.37 44.48 42.81 28.45 26.92 27.81 43.55333333 27.72666667 1220 1127 1154 1602 1167 7.81E-10 -0.467950385 00514///Other types of O-glycan biosynthesis+++04330///Notch signaling pathway+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0033829///O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity+++GO:0046872///metal ion binding" GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0008593///regulation of Notch signaling pathway+++GO:0030154///cell differentiation+++GO:0032092///positive regulation of protein binding+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045747///positive regulation of Notch signaling pathway 19720 19720 'Trim27' mRNA 931.59 913.56 295.36 20.77 20.31 6.78 9.67 22.12 18.61 15.95333333 16.8 499.94 1092.47 916.21 713.5033333 836.2066667 0.759283312 0.247917108 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0030904///retromer complex+++GO:0031965///nuclear membrane GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0002820///negative regulation of adaptive immune response+++GO:0006469///negative regulation of protein kinase activity+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032880///regulation of protein localization+++GO:0032897///negative regulation of viral transcription+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051127///positive regulation of actin nucleation+++GO:0070534///protein K63-linked ubiquitination+++GO:0090281///negative regulation of calcium ion import+++GO:1902187///negative regulation of viral release from host cell" 19724 19724 'Rfx1' mRNA 902.83 960.4 848.83 8.31 8.89 7.63 5.2 5.49 5.07 8.276666667 5.253333333 556 574 533.98 904.02 554.66 4.76E-13 -0.714502587 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 19725 19725 'Rfx2' mRNA 377 428 389 6.26 6.97 6.85 1.45 1.39 1.72 6.693333333 1.52 100 95 115 398 103.3333333 1.44E-31 -1.956837771 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001675///acrosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060271///cilium assembly+++GO:1990830///cellular response to leukemia inhibitory factor" 19726 19726 'Rfx3' mRNA 1488 1563 1414 8 8.22 8.1 2.02 1.73 1.94 8.106666667 1.896666667 460 381 414 1488.333333 418.3333333 2.50E-87 -1.842873184 GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0030154///cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0050796///regulation of insulin secretion+++GO:0060271///cilium assembly+++GO:0060285///cilium-dependent cell motility+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0072560///type B pancreatic cell maturation+++GO:2000078///positive regulation of type B pancreatic cell development" 19727 19727 'Rfxank' mRNA 725.94 669.5 662.86 10.75 9.77 10.42 8.14 8.04 8.46 10.31333333 8.213333333 632.49 609.49 636.61 686.1 626.1966667 0.22759083 -0.143088599 04612///Antigen processing and presentation+++05152///Tuberculosis+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007265///Ras protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 19729 19729 'Slc50a1' mRNA 1172 1115 1203 74.11 70.23 81.9 72.1 72.58 69.37 75.41333333 71.35 1306 1287 1215 1163.333333 1269.333333 0.286540939 0.111832702 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042947///glucoside transmembrane transporter activity+++GO:0051119///sugar transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0034219///carbohydrate transmembrane transport+++GO:0042946///glucoside transport 19730 19730 'Ralgds' mRNA 1083 1071 926 16.28 15.89 14.83 42.68 47.04 46.23 15.66666667 45.31666667 3259 3515 3432 1026.666667 3402 7.22E-120 1.720016912 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005903///brush border GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 19731 19731 'Rgl1' mRNA 1420 1485 1086 16.04 16.78 12.69 9.72 11.2 10.92 15.17 10.61333333 909 1025 1000 1330.333333 978 2.71E-05 -0.448358567 04014///Ras signaling pathway GO:0005085///guanyl-nucleotide exchange factor activity GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 19732 19732 'Rgl2' mRNA 1082 1175 859 19.95 21.41 16.81 16.68 19.35 18.9 19.39 18.31 1031 1166 1130 1038.666667 1109 0.491467009 0.089692053 04014///Ras signaling pathway GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0032485///regulation of Ral protein signal transduction+++GO:0044030///regulation of DNA methylation+++GO:0050790///regulation of catalytic activity+++GO:0097692///histone H3-K4 monomethylation 19733 19733 'Rgn' mRNA 18 14 6 0.67 0.51 0.24 0.58 0.9 0.4 0.473333333 0.626666667 18 27 12 12.66666667 19 0.459693655 0.59051621 00030///Pentose phosphate pathway+++00053///Ascorbate and aldarate metabolism+++01200///Carbon metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004341///gluconolactonase activity+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0030234///enzyme regulator activity+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0001889///liver development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006874///cellular calcium ion homeostasis+++GO:0007283///spermatogenesis+++GO:0007568///aging+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010922///positive regulation of phosphatase activity+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032781///positive regulation of ATPase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0097421///liver regeneration+++GO:1901318///negative regulation of flagellated sperm motility+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:1902679///negative regulation of RNA biosynthetic process+++GO:1903011///negative regulation of bone development+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:1903611///negative regulation of calcium-dependent ATPase activity+++GO:1903625///negative regulation of DNA catabolic process+++GO:1903629///positive regulation of dUTP diphosphatase activity+++GO:1903634///negative regulation of leucine-tRNA ligase activity+++GO:2000279///negative regulation of DNA biosynthetic process 19734 19734 'Rgs16' mRNA 172 189 199 4.13 4.47 5.07 16.89 13.55 14.02 4.556666667 14.82 809 634 650 186.6666667 697.6666667 9.04E-41 1.886074219 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031224///intrinsic component of membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0001965///G-protein alpha-subunit binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0032794///GTPase activating protein binding GO:0000278///mitotic cell cycle+++GO:0006913///nucleocytoplasmic transport+++GO:0006979///response to oxidative stress+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008542///visual learning+++GO:0009968///negative regulation of signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050769///positive regulation of neurogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051301///cell division+++GO:0060291///long-term synaptic potentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 19735 19735 'Rgs2' mRNA 1890 2100 1999 34.5 37.72 38.7 43.57 43.45 40.32 36.97333333 42.44666667 2747 2675 2461 1996.333333 2627.666667 5.79E-07 0.3838104 04022///cGMP-PKG signaling pathway+++04740///Olfactory transduction+++04921///Oxytocin signaling pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0010855///adenylate cyclase inhibitor activity+++GO:0048487///beta-tubulin binding GO:0001975///response to amphetamine+++GO:0006417///regulation of translation+++GO:0007049///cell cycle+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0010519///negative regulation of phospholipase activity+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010976///positive regulation of neuron projection development+++GO:0017148///negative regulation of translation+++GO:0030728///ovulation+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045471///response to ethanol+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0050873///brown fat cell differentiation+++GO:0055119///relaxation of cardiac muscle+++GO:0060087///relaxation of vascular smooth muscle+++GO:0060135///maternal process involved in female pregnancy+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0140194///negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process+++GO:1900924///negative regulation of glycine import across plasma membrane 19736 19736 'Rgs4' mRNA 458 552 497 8.57 10.16 9.86 24.61 22.92 23.1 9.53 23.54333333 1514 1377 1376 502.3333333 1422.333333 5.25E-54 1.48928306 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity GO:0001975///response to amphetamine+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0009968///negative regulation of signal transduction+++GO:0010460///positive regulation of heart rate+++GO:0042220///response to cocaine+++GO:0043278///response to morphine+++GO:0043547///positive regulation of GTPase activity+++GO:0045471///response to ethanol+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0051924///regulation of calcium ion transport+++GO:0060160///negative regulation of dopamine receptor signaling pathway+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0110053///regulation of actin filament organization+++GO:1900924///negative regulation of glycine import across plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1990791///dorsal root ganglion development+++GO:2000463///positive regulation of excitatory postsynaptic potential 19737 19737 'Rgs5' mRNA 2774 2876 3094 37.4 38.88 45.3 31.31 30.95 30.55 40.52666667 30.93666667 2675 2548 2458 2914.666667 2560.333333 0.017243423 -0.202338403 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0050790///regulation of catalytic activity+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation 19739 19739 'Rgs9' mRNA 436 459 395 5.16 5.08 4.84 2.18 1.66 1.97 5.026666667 1.936666667 208 157 204 430 189.6666667 3.74E-15 -1.19207472 04744///Phototransduction+++05030///Cocaine addiction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0001975///response to amphetamine+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0032355///response to estradiol+++GO:0035556///intracellular signal transduction+++GO:0036367///light adaption+++GO:0050790///regulation of catalytic activity+++GO:0050896///response to stimulus+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:1905912///regulation of calcium ion export across plasma membrane+++GO:1990603///dark adaptation 19743 19743 'Rhag' mRNA 5 1 3.98 0.1 0.01 0.05 0.04 0.06 0.04 0.053333333 0.046666667 2 4 4 3.326666667 3.333333333 0.938739053 0.141486845 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008519///ammonium transmembrane transporter activity+++GO:0022840///leak channel activity+++GO:0030506///ankyrin binding GO:0006873///cellular ion homeostasis+++GO:0015670///carbon dioxide transport+++GO:0015696///ammonium transport+++GO:0048821///erythrocyte development+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0072488///ammonium transmembrane transport+++GO:0098662///inorganic cation transmembrane transport 19744 19744 'Rheb' mRNA 1962 2074 1838 76.06 79.3 75.6 66.89 82.7 72.8 76.98666667 74.13 1982 2391 2087 1958 2153.333333 0.19330618 0.128799023 04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05231///Choline metabolism in cancer GO:0000139///Golgi membrane+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0032006///regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0099175///regulation of postsynapse organization+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:2000074///regulation of type B pancreatic cell development 19746 19746 'Rhd' mRNA 0 2 2 0 0.08 0.08 0.31 0.42 0.25 0.053333333 0.326666667 9 12 7 1.333333333 9.333333333 0.032850669 2.791555872 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008519///ammonium transmembrane transporter activity GO:0015696///ammonium transport+++GO:0048821///erythrocyte development+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0072488///ammonium transmembrane transport 19752 19752 'Rnase1' mRNA 6125 6317 6070 406.8 415.03 427.78 184.37 191.97 178.33 416.5366667 184.89 3182 3229 2974 6170.666667 3128.333333 2.15E-60 -0.99192251 GO:0005576///extracellular region GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004522///ribonuclease A activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity "GO:0009617///response to bacterium+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 19762 19762 'Rit2' mRNA 0 1 0 0 0.03 0 0.06 0.09 0.03 0.01 0.06 2 3 1 0.333333333 2 0.381767266 2.471967214 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0097447///dendritic tree GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0030215///semaphorin receptor binding GO:0000165///MAPK cascade+++GO:0001932///regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0030100///regulation of endocytosis+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0032507///maintenance of protein location in cell+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050848///regulation of calcium-mediated signaling+++GO:0070372///regulation of ERK1 and ERK2 cascade 19763 19763 'Ring1' mRNA 929 947 70 25.96 26.07 2.07 2.55 8.54 6.78 18.03333333 5.956666667 105 343 270 648.6666667 239.3333333 0.251790402 -1.403492239 GO:0000151///ubiquitin ligase complex+++GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097027///ubiquitin-protein transferase activator activity "GO:0006325///chromatin organization+++GO:0009952///anterior/posterior pattern specification+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0035518///histone H2A monoubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048593///camera-type eye morphogenesis+++GO:0050790///regulation of catalytic activity" 19765 19765 'Ralbp1' mRNA 2300 2136 1387 33.41 30.76 20.72 18.06 19.85 18.94 28.29666667 18.95 1464 1551 1474 1941 1496.333333 0.003013263 -0.37662677 04014///Ras signaling pathway+++05200///Pathways in cancer+++05212///Pancreatic cancer GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection "GO:0000166///nucleotide binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0031267///small GTPase binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity" GO:0001934///positive regulation of protein phosphorylation+++GO:0006897///endocytosis+++GO:0007052///mitotic spindle organization+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0032489///regulation of Cdc42 protein signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0055085///transmembrane transport+++GO:0090141///positive regulation of mitochondrial fission+++GO:1900753///doxorubicin transport+++GO:1903378///positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1990961///drug transmembrane export 19766 19766 'Ripk1' mRNA 493.21 542.72 233.77 4.56 4.77 2.04 3.57 3.78 4.91 3.79 4.086666667 408.98 433.16 570.95 423.2333333 471.03 0.751368437 0.161281815 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05160///Hepatitis C+++05163///Human cytomegalovirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031264///death-inducing signaling complex+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0097342///ripoptosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0070513///death domain binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007257///activation of JUN kinase activity+++GO:0008219///cell death+++GO:0010940///positive regulation of necrotic cell death+++GO:0010942///positive regulation of cell death+++GO:0012501///programmed cell death+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034612///response to tumor necrosis factor+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0042327///positive regulation of phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043068///positive regulation of programmed cell death+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044257///cellular protein catabolic process+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0050729///positive regulation of inflammatory response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051347///positive regulation of transferase activity+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060545///positive regulation of necroptotic process+++GO:0060546///negative regulation of necroptotic process+++GO:0070105///positive regulation of interleukin-6-mediated signaling pathway+++GO:0070231///T cell apoptotic process+++GO:0070266///necroptotic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070926///regulation of ATP:ADP antiporter activity+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097300///programmed necrotic cell death+++GO:0097343///ripoptosome assembly+++GO:0097527///necroptotic signaling pathway+++GO:1901026///ripoptosome assembly involved in necroptotic process+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1905206///positive regulation of hydrogen peroxide-induced cell death+++GO:1990000///amyloid fibril formation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 19769 19769 'Rit1' mRNA 1082 1115 1126 23.95 24.31 26.48 27.58 24.43 25.62 24.91333333 25.87666667 1433 1238 1288 1107.666667 1319.666667 0.010484356 0.238458591 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction 19771 19771 'Rlbp1' mRNA 4197 4331 4245 119.57 121.19 128.62 28.84 27.87 28.85 123.1266667 28.52 1191 1107 1134 4257.666667 1144 4.03E-180 -1.90895757 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0044297///cell body GO:0005502///11-cis retinal binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:1902936///phosphatidylinositol bisphosphate binding GO:0007601///visual perception+++GO:0050896///response to stimulus 19775 19775 'Xpr1' mRNA 761 811 682 5.24 5.49 4.98 4.43 3.73 4.88 5.236666667 4.346666667 741 609 791 751.3333333 713.6666667 0.5571152 -0.084448818 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031902///late endosome membrane+++GO:0035658///Mon1-Ccz1 complex GO:0000822///inositol hexakisphosphate binding+++GO:0001618///virus receptor activity+++GO:0015114///phosphate ion transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity GO:0006817///phosphate ion transport+++GO:0006914///autophagy+++GO:0009615///response to virus+++GO:0010506///regulation of autophagy+++GO:0016036///cellular response to phosphate starvation+++GO:0030643///cellular phosphate ion homeostasis+++GO:0035435///phosphate ion transmembrane transport+++GO:0046718///viral entry into host cell 19777 19777 'Uri1' mRNA 885 983 366 13.96 15.26 6.59 5.26 6.3 6.07 11.93666667 5.876666667 364 449 425 744.6666667 412.6666667 0.061201658 -0.840889663 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0000993///RNA polymerase II complex binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0019212///phosphatase inhibitor activity+++GO:0051219///phosphoprotein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009615///response to virus+++GO:0010923///negative regulation of phosphatase activity+++GO:0071363///cellular response to growth factor stimulus+++GO:0071383///cellular response to steroid hormone stimulus+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 19819 19819 'Rnaseh1' mRNA 237 259 182 9.66 10.41 7.87 11.74 9.34 10.45 9.313333333 10.51 331 257 285 226 291 0.051167699 0.356704619 03030///DNA replication GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000287///magnesium ion binding+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006264///mitochondrial DNA replication+++GO:0043137///DNA replication, removal of RNA primer+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 19820 19820 'Rlim' mRNA 1306.01 1236 1077 8.75 8.2 7.78 9.9 8.31 9.1 8.243333333 9.103333333 1669.99 1377 1479 1206.336667 1508.663333 6.50E-04 0.311684507 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0060816///random inactivation of X chromosome+++GO:1900095///regulation of dosage compensation by inactivation of X chromosome 19821 19821 'Rnf2' mRNA 1024 1112 1127 17.45 18.66 20.37 17.73 18.28 17.69 18.82666667 17.9 1199 1206 1159 1087.666667 1188 0.28613632 0.113905221 GO:0000151///ubiquitin ligase complex+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex+++GO:0071339///MLL1 complex GO:0003682///chromatin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0071535///RING-like zinc finger domain binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0001702///gastrulation with mouth forming second+++GO:0007281///germ cell development+++GO:0009948///anterior/posterior axis specification+++GO:0010467///gene expression+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0035518///histone H2A monoubiquitination+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0043433///negative regulation of DNA-binding transcription factor activity 19822 19822 'Rnf4' mRNA 1897 2071 2129 34.72 37.42 41.51 46.01 44.86 46.13 37.88333333 45.66666667 2870 2753 2786 2032.333333 2803 8.63E-09 0.449533195 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:1990752///microtubule end GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017025///TBP-class protein binding+++GO:0030331///estrogen receptor binding+++GO:0031491///nucleosome binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032184///SUMO polymer binding+++GO:0033142///progesterone receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046685///response to arsenic-containing substance+++GO:0051865///protein autoubiquitination+++GO:0060548///negative regulation of cell death+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0071394///cellular response to testosterone stimulus+++GO:0071480///cellular response to gamma radiation+++GO:0072711///cellular response to hydroxyurea+++GO:0085020///protein K6-linked ubiquitination+++GO:0090169///regulation of spindle assembly+++GO:0090234///regulation of kinetochore assembly" 19823 19823 'Rnf7' mRNA 3029 3225 2783 150.23 157.94 146.45 155.09 151.97 151.4 151.54 152.82 3589 3430 3388 3012.333333 3469 0.002193253 0.19362403 04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0061663///NEDD8 ligase activity+++GO:0097602///cullin family protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0008637///apoptotic mitochondrial changes+++GO:0016567///protein ubiquitination+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045116///protein neddylation 19824 19824 'Trim10' mRNA 5 5 2 0.13 0.12 0.05 0.04 0 0.05 0.1 0.03 2 0 2 4 1.333333333 0.392523956 -1.588690677 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0030218///erythrocyte differentiation+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell 19826 19826 'Rnps1' mRNA 2428 2459 2323 78.52 79 78.95 76.08 74.28 78.96 78.82333333 76.44 2620 2493 2604 2403.333333 2572.333333 0.238497515 0.086452249 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0061574///ASAP complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 19876 19876 'Robo1' mRNA 1374.38 1310 1152.95 9.44 8.89 8.37 4.4 3.87 4.02 8.9 4.096666667 736 636.09 655 1279.11 675.6966667 3.72E-24 -0.930636438 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030673///axolemma+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0008046///axon guidance receptor activity+++GO:0030275///LRR domain binding+++GO:0042802///identical protein binding GO:0001822///kidney development+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003272///endocardial cushion formation+++GO:0003281///ventricular septum development+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006935///chemotaxis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016199///axon midline choice point recognition+++GO:0021836///chemorepulsion involved in postnatal olfactory bulb interneuron migration+++GO:0021891///olfactory bulb interneuron development+++GO:0030154///cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035385///Roundabout signaling pathway+++GO:0035481///positive regulation of Notch signaling pathway involved in heart induction+++GO:0035904///aorta development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0050925///negative regulation of negative chemotaxis+++GO:0060412///ventricular septum morphogenesis+++GO:0060763///mammary duct terminal end bud growth+++GO:0060976///coronary vasculature development+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway 19877 19877 'Rock1' mRNA 873 927 865 7.42 7.74 7.85 8.95 7.9 8.98 7.67 8.61 1208 1040 1173 888.3333333 1140.333333 1.87E-04 0.347854316 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04270///Vascular smooth muscle contraction+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0000139///Golgi membrane+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0032059///bleb+++GO:0042995///cell projection+++GO:0106003///amyloid-beta complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0072518///Rho-dependent protein serine/threonine kinase activity GO:0000281///mitotic cytokinesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0003383///apical constriction+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007266///Rho protein signal transduction+++GO:0010508///positive regulation of autophagy+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0022614///membrane to membrane docking+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0031175///neuron projection development+++GO:0032060///bleb assembly+++GO:0032091///negative regulation of protein binding+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0032970///regulation of actin filament-based process+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0035556///intracellular signal transduction+++GO:0042326///negative regulation of phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045616///regulation of keratinocyte differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0048598///embryonic morphogenesis+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0051451///myoblast migration+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0061157///mRNA destabilization+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071559///response to transforming growth factor beta+++GO:0072659///protein localization to plasma membrane+++GO:0090521///glomerular visceral epithelial cell migration+++GO:0097746///regulation of blood vessel diameter+++GO:0110061///regulation of angiotensin-activated signaling pathway+++GO:0140058///neuron projection arborization+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1901888///regulation of cell junction assembly+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902992///negative regulation of amyloid precursor protein catabolic process+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1903347///negative regulation of bicellular tight junction assembly+++GO:1905205///positive regulation of connective tissue replacement+++GO:1990776///response to angiotensin 19878 19878 'Rock2' mRNA 617 550 587 4.05 3.59 4.09 5.2 4.81 5.12 3.91 5.043333333 903 824 870 584.6666667 865.6666667 1.33E-07 0.552758728 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04071///Sphingolipid signaling pathway+++04270///Vascular smooth muscle contraction+++04310///Wnt signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031616///spindle pole centrosome+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0072518///Rho-dependent protein serine/threonine kinase activity GO:0000281///mitotic cytokinesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001843///neural tube closure+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007266///Rho protein signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010825///positive regulation of centrosome duplication+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0031644///regulation of neurological system process+++GO:0032723///positive regulation of connective tissue growth factor production+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0035556///intracellular signal transduction+++GO:0039694///viral RNA genome replication+++GO:0042752///regulation of circadian rhythm+++GO:0043410///positive regulation of MAPK cascade+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045616///regulation of keratinocyte differentiation+++GO:0048511///rhythmic process+++GO:0048598///embryonic morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0051246///regulation of protein metabolic process+++GO:0051298///centrosome duplication+++GO:0051496///positive regulation of stress fiber assembly+++GO:0061157///mRNA destabilization+++GO:0071394///cellular response to testosterone stimulus+++GO:0071559///response to transforming growth factor beta+++GO:0072659///protein localization to plasma membrane+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:0097746///regulation of blood vessel diameter+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0110061///regulation of angiotensin-activated signaling pathway+++GO:0150033///negative regulation of protein localization to lysosome+++GO:1900037///regulation of cellular response to hypoxia+++GO:1901888///regulation of cell junction assembly+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1903347///negative regulation of bicellular tight junction assembly+++GO:1905145///cellular response to acetylcholine+++GO:1905205///positive regulation of connective tissue replacement+++GO:1990776///response to angiotensin 19879 19879 'Slc22a8' mRNA 85 80 100 1.33 1.19 1.65 1.16 0.85 0.73 1.39 0.913333333 84 59 52 88.33333333 65 0.167122545 -0.462859296 04976///Bile secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0005080///protein kinase C binding+++GO:0005452///inorganic anion exchanger activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0009636///response to toxic substance+++GO:0015697///quaternary ammonium group transport+++GO:0015698///inorganic anion transport+++GO:0034635///glutathione transport+++GO:0055085///transmembrane transport 19881 19881 'Rom1' mRNA 192 203 196 7.42 7.73 8.03 6.49 7.41 7.26 7.726666667 7.053333333 193 215 209 197 205.6666667 0.844396003 0.051087332 GO:0001750///photoreceptor outer segment+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0042803///protein homodimerization activity GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0010468///regulation of gene expression+++GO:0035845///photoreceptor cell outer segment organization+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0051260///protein homooligomerization+++GO:0051291///protein heterooligomerization+++GO:0060041///retina development in camera-type eye+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060219///camera-type eye photoreceptor cell differentiation+++GO:0061298///retina vasculature development in camera-type eye+++GO:1903546///protein localization to photoreceptor outer segment 19882 19882 'Mst1r' mRNA 32 15 31 0.84 0.41 0.41 0.14 0.26 0.29 0.553333333 0.23 12 20 19 26 17 0.336293654 -0.629684978 04020///Calcium signaling pathway GO:0001725///stress fiber+++GO:0005773///vacuole+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009615///response to virus+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045087///innate immune response+++GO:0051897///positive regulation of protein kinase B signaling 19883 19883 'Rora' mRNA 4114 4065 3511 14.3 15.92 12.2 7.82 6.94 6.41 14.14 7.056666667 2604 2136 2245 3896.666667 2328.333333 3.89E-25 -0.753730034 04659///Th17 cell differentiation+++04710///Circadian rhythm+++05017///Spinocerebellar ataxia+++05321///Inflammatory bowel disease GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008142///oxysterol binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0098531///transcription factor activity, direct ligand regulated sequence-specific DNA binding" "GO:0001525///angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006805///xenobiotic metabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007623///circadian rhythm+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010906///regulation of glucose metabolic process+++GO:0019218///regulation of steroid metabolic process+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021930///cerebellar granule cell precursor proliferation+++GO:0030522///intracellular receptor signaling pathway+++GO:0032922///circadian regulation of gene expression+++GO:0036315///cellular response to sterol+++GO:0042632///cholesterol homeostasis+++GO:0042692///muscle cell differentiation+++GO:0042752///regulation of circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0043030///regulation of macrophage activation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046068///cGMP metabolic process+++GO:0048511///rhythmic process+++GO:0050728///negative regulation of inflammatory response+++GO:0070328///triglyceride homeostasis+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071456///cellular response to hypoxia+++GO:0072539///T-helper 17 cell differentiation" 19885 19885 'Rorc' mRNA 854 821 794 23.27 22.35 22.22 12.91 12.53 14.47 22.61333333 13.30333333 562 513 584 823 553 1.52E-08 -0.585451783 04659///Th17 cell differentiation+++04710///Circadian rhythm+++05321///Inflammatory bowel disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0009897///external side of plasma membrane+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008142///oxysterol binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0098531///transcription factor activity, direct ligand regulated sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006805///xenobiotic metabolic process+++GO:0007275///multicellular organism development+++GO:0007623///circadian rhythm+++GO:0010906///regulation of glucose metabolic process+++GO:0019218///regulation of steroid metabolic process+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0032620///interleukin-17 production+++GO:0032922///circadian regulation of gene expression+++GO:0033077///T cell differentiation in thymus+++GO:0036315///cellular response to sterol+++GO:0042093///T-helper cell differentiation+++GO:0042753///positive regulation of circadian rhythm+++GO:0045586///regulation of gamma-delta T cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046632///alpha-beta T cell differentiation+++GO:0048511///rhythmic process+++GO:0048535///lymph node development+++GO:0048537///mucosal-associated lymphoid tissue development+++GO:0048541///Peyer's patch development+++GO:0060612///adipose tissue development+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0072539///T-helper 17 cell differentiation" 19886 19886 'Ros1' mRNA 61 37 33 0.43 0.24 0.24 0.05 0.01 0.04 0.303333333 0.033333333 10 1 6 43.66666667 5.666666667 3.17E-06 -2.95927056 04013///MAPK signaling pathway - fly GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding GO:0001558///regulation of cell growth+++GO:0002066///columnar/cuboidal epithelial cell development+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010467///gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010966///regulation of phosphate transport+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0032006///regulation of TOR signaling+++GO:0033674///positive regulation of kinase activity+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0070372///regulation of ERK1 and ERK2 cascade 19888 19888 'Rp1' mRNA 5 9 5 0.08 0.13 0.08 0.15 0.22 0.17 0.096666667 0.18 12 17 13 6.333333333 14 0.18577504 1.142048175 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005875///microtubule associated complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection+++GO:0097542///ciliary tip+++GO:0097733///photoreceptor cell cilium GO:0008017///microtubule binding GO:0007026///negative regulation of microtubule depolymerization+++GO:0007601///visual perception+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0035556///intracellular signal transduction+++GO:0035845///photoreceptor cell outer segment organization+++GO:0042461///photoreceptor cell development+++GO:0045494///photoreceptor cell maintenance+++GO:0046548///retinal rod cell development+++GO:0046549///retinal cone cell development+++GO:0046785///microtubule polymerization+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0071482///cellular response to light stimulus+++GO:1902857///positive regulation of non-motile cilium assembly 19889 19889 'Rp2' mRNA 533.13 572 582.78 7.63 7.57 7.47 13.06 9.45 11.74 7.556666667 11.41666667 1054.9 876.01 923.11 562.6366667 951.34 4.88E-12 0.743116451 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:1990075///periciliary membrane compartment GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005096///GTPase activator activity+++GO:0005525///GTP binding GO:0000902///cell morphogenesis+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0007023///post-chaperonin tubulin folding pathway+++GO:0015031///protein transport+++GO:0050790///regulation of catalytic activity 19891 19891 'Rpa2' mRNA 391 374 345 12.66 11.94 11.85 14.68 15.82 16.19 12.15 15.56333333 521 548 556 370 541.6666667 1.11E-05 0.54012168 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination+++03460///Fanconi anemia pathway "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0035861///site of double-strand break" GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0047485///protein N-terminus binding+++GO:0098505///G-rich strand telomeric DNA binding GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006298///mismatch repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0034502///protein localization to chromosome+++GO:2000001///regulation of DNA damage checkpoint 19893 19893 'Rpgr' mRNA 540 606 525 9.96 10.92 10.32 3.12 3.24 2.74 10.4 3.033333333 198 207 160 557 188.3333333 2.10E-28 -1.574569529 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0007601///visual perception+++GO:0030030///cell projection organization+++GO:0042073///intraciliary transport+++GO:0042462///eye photoreceptor cell development+++GO:0050790///regulation of catalytic activity+++GO:0050896///response to stimulus+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060271///cilium assembly+++GO:0071482///cellular response to light stimulus 19894 19894 'Rph3a' mRNA 139 163 106 1.88 2.14 1.5 0.2 0.14 0.23 1.84 0.19 17 12 18 136 15.66666667 5.23E-20 -3.123261243 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098981///cholinergic synapse "GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0008430///selenium binding+++GO:0031267///small GTPase binding+++GO:0042301///phosphate ion binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0046879///hormone secretion+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0097061///dendritic spine organization+++GO:2000310///regulation of NMDA receptor activity 19895 19895 'Rpia' mRNA 17 9 17 0.55 0.29 0.59 0.48 0.41 0.7 0.476666667 0.53 17 14 24 14.33333333 18.33333333 0.683019115 0.335568424 00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0043231///intracellular membrane-bounded organelle GO:0004751///ribose-5-phosphate isomerase activity+++GO:0016853///isomerase activity+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0048029///monosaccharide binding "GO:0006014///D-ribose metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0009052///pentose-phosphate shunt, non-oxidative branch+++GO:0019693///ribose phosphate metabolic process" 19896 19896 'Rpl10a' mRNA 2487 2511 2314 198.29 197.67 195.68 276.53 252.65 275.03 197.2133333 268.07 3992 3549 3818 2437.333333 3786.333333 4.36E-24 0.62386171 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0000470///maturation of LSU-rRNA+++GO:0002181///cytoplasmic translation+++GO:0006412///translation 19899 19899 'Rpl18' mRNA 4067 3959 3777 426.77 412.44 420.68 538.45 549.71 567.42 419.9633333 551.86 5872 5811 5945 3934.333333 5876 6.60E-25 0.56756796 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation 19921 19921 'Rpl19' mRNA 5578.34 5518.12 5345.03 515.35 505.35 524.04 791.41 759.12 816.32 514.9133333 788.95 9801.45 9144.52 9756.79 5480.496667 9567.586667 2.70E-51 0.791595672 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0070180///large ribosomal subunit rRNA binding+++GO:1990932///5.8S rRNA binding GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0097421///liver regeneration 19933 19933 'Rpl21' mRNA 3034.28 2954.53 3000.01 93.88 90.08 98.47 100.37 109.14 106.67 94.14333333 105.3933333 3728.92 3957.99 3835.37 2996.273333 3840.76 5.82E-07 0.346008144 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0006412///translation 19934 19934 'Rpl22' mRNA 1211 1354 1322 31.16 34.42 35.97 33.2 31.92 34.8 33.85 33.30666667 1492 1401 1514 1295.666667 1469 0.074569721 0.167938378 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0045182///translation regulator activity "GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0046632///alpha-beta T cell differentiation+++GO:0099577///regulation of translation at presynapse, modulating synaptic transmission" 19935 19935 'Mrpl23' mRNA 1247 1222 1179 135.54 131.22 137.5 120.57 130.49 130.44 134.7533333 127.1666667 1262 1330 1311 1216 1301 0.380628492 0.086563765 03010///Ribosome GO:0001650///fibrillar center+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 19941 19941 'Rpl26' mRNA 2638 2649 2747 391.58 392.44 432.89 448.75 507.66 494.93 405.6366667 483.78 3443 3782 3656 2678 3627 2.68E-08 0.425096505 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0043195///terminal bouton+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0048027///mRNA 5'-UTR binding "GO:0002181///cytoplasmic translation+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0034644///cellular response to UV+++GO:0042273///ribosomal large subunit biogenesis+++GO:0045727///positive regulation of translation+++GO:0071479///cellular response to ionizing radiation+++GO:0071480///cellular response to gamma radiation+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1904803///regulation of translation involved in cellular response to UV" 19942 19942 'Rpl27' mRNA 2520 2205 2446 240.97 209.23 248.22 245.99 250.5 269.02 232.8066667 255.17 2942 2916 3105 2390.333333 2987.666667 1.95E-04 0.308072088 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:1990904///ribonucleoprotein complex GO:0003735///structural constituent of ribosome GO:0006364///rRNA processing+++GO:0006412///translation+++GO:1904044///response to aldosterone 19943 19943 'Rpl28' mRNA 1625 1551 1546 279.12 266.56 281.97 292.98 327.75 310.26 275.8833333 310.33 1939 2104 1975 1574 2006 2.42E-05 0.338658739 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0030425///dendrite+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0044297///cell body GO:0003735///structural constituent of ribosome GO:0006412///translation 19944 19944 'Rpl29' mRNA 1627.35 1589.8 1479.7 141.83 138.19 137.29 230.04 224.79 244.75 139.1033333 233.1933333 2994.99 2868.73 3100.92 1565.616667 2988.213333 1.87E-43 0.921897038 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0019898///extrinsic component of membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0008201///heparin binding GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0008283///cell proliferation+++GO:0031589///cell-substrate adhesion+++GO:0035264///multicellular organism growth 19946 19946 'Rpl30' mRNA 1480.14 1368.82 1530.82 231.16 212.91 251.74 287.25 295.86 304.67 231.9366667 295.9266667 2115.47 2138.1 2159.78 1459.926667 2137.783333 2.82E-10 0.536283819 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0035368///selenocysteine insertion sequence binding GO:0002181///cytoplasmic translation+++GO:0031640///killing of cells of other organism+++GO:0050829///defense response to Gram-negative bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0097421///liver regeneration+++GO:1904571///positive regulation of selenocysteine incorporation 19951 19951 'Rpl32' mRNA 3068 2954 3060.99 513.26 494.22 543.72 621.7 694.78 675.15 517.0666667 663.8766667 4225.99 4582 4415 3027.663333 4407.663333 9.48E-14 0.529618508 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0097421///liver regeneration 19981 19981 'Rpl37a' mRNA 3212 3161 3943 421.89 413.61 549.77 381.69 373.24 435.71 461.7566667 396.88 3314 3149 3645 3438.666667 3369.333333 0.737431661 -0.047986665 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003735///structural constituent of ribosome+++GO:0046872///metal ion binding+++GO:0070180///large ribosomal subunit rRNA binding GO:0006412///translation 19982 19982 'Rpl36a' mRNA 1195 1132 1395 210.18 199.29 260.53 233.08 241.61 262.65 223.3333333 245.78 1505.99 1514 1632 1240.666667 1550.663333 0.00671335 0.304497666 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome GO:0003674///molecular_function+++GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0008150///biological_process 19988 19988 'Rpl6' mRNA 4933.2 4959.98 4926.72 240.16 238.46 254.41 356.18 346.83 358.52 244.3433333 353.8433333 8393.41 7974.07 8170.17 4939.966667 8179.216667 1.14E-38 0.714734606 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0031672///A band+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:1990932///5.8S rRNA binding GO:0000027///ribosomal large subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0006412///translation 19989 19989 'Rpl7' mRNA 5718 5730 5369 398.33 395 396.88 443.27 427.14 451.32 396.7366667 440.5766667 7292 6847 7173 5605.666667 7104 1.78E-10 0.330262438 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0031672///A band+++GO:0042788///polysomal ribosome+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0042802///identical protein binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis" 20005 20005 'Rpl9' mRNA 5429.6 5276.78 5127.58 528.04 509.34 529.24 623.36 581.38 598.57 522.2066667 601.1033333 7329.45 6652.84 6791.38 5277.986667 6924.556667 1.08E-11 0.379256279 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0002181///cytoplasmic translation+++GO:0006412///translation 20014 20014 'Rpn2' mRNA 7351.73 7304.07 7676.21 160.94 158.2 178.77 173.54 169.5 169.38 165.97 170.8066667 9203.35 8817.26 8744.36 7444.003333 8921.656667 1.27E-04 0.246925034 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0000421///autophagosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0043022///ribosome binding GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0007568///aging+++GO:0042493///response to drug 20016 20016 'Polr1c' mRNA 670 757 668 31.04 34.62 32.83 28.57 30.82 28.04 32.83 29.14333333 708 745 672 698.3333333 708.3333333 0.943804483 0.010262352 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex GO:0001054///RNA polymerase I activity+++GO:0001056///RNA polymerase III activity+++GO:0001179///RNA polymerase I transcription factor binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity "GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006351///transcription, DNA-templated+++GO:0006360///transcription by RNA polymerase I+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006383///transcription by RNA polymerase III+++GO:0008150///biological_process+++GO:0042790///nucleolar large rRNA transcription by RNA polymerase I" 20017 20017 'Polr1b' mRNA 378.46 358.84 375.94 5.04 4.7 5.36 4.35 3.92 3.95 5.033333333 4.073333333 377.67 329.63 329.95 371.08 345.75 0.492297238 -0.116291287 03020///RNA polymerase GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0032549///ribonucleoside binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0007566///embryo implantation+++GO:0009303///rRNA transcription+++GO:0009790///embryo development+++GO:0014029///neural crest formation+++GO:0017126///nucleologenesis" 20018 20018 'Polr1d' mRNA 1142 1081 1035 77.59 72.21 75.46 92.9 97.85 90.73 75.08666667 93.82666667 1538 1580 1436 1086 1518 1.65E-08 0.472300562 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex+++GO:0005736///RNA polymerase I complex GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity "GO:0006351///transcription, DNA-templated" 20019 20019 'Polr1a' mRNA 969 921 805 8.65 8.19 7.41 5.45 5.04 5.7 8.083333333 5.396666667 723 653 733 898.3333333 703 3.56E-04 -0.363424885 03020///RNA polymerase GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex GO:0001054///RNA polymerase I activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006360///transcription by RNA polymerase I+++GO:0009303///rRNA transcription+++GO:1904750///negative regulation of protein localization to nucleolus" 20020 20020 'Polr2a' mRNA 2334 2141 1627 18.32 16.52 13.54 17.44 15.5 14.7 16.12666667 15.88 2559 2222 2090 2034 2290.333333 0.142505086 0.164276258 03020///RNA polymerase+++05016///Huntington disease "GO:0000791///euchromatin+++GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm" GO:0001046///core promoter sequence-specific DNA binding+++GO:0001055///RNA polymerase II activity+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding "GO:0006351///transcription, DNA-templated+++GO:0006353///DNA-templated transcription, termination+++GO:0006366///transcription by RNA polymerase II+++GO:0014070///response to organic cyclic compound+++GO:0033120///positive regulation of RNA splicing+++GO:0071453///cellular response to oxygen levels" 20021 20021 'Polr2c' mRNA 1535.8 1592.24 1525.53 57 58.27 60.07 61.03 63.5 63.46 58.44666667 62.66333333 1889.33 1918.22 1900.56 1551.19 1902.703333 1.68E-04 0.283336476 03020///RNA polymerase+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol" GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 20022 20022 'Polr2j' mRNA 601 670 697 79.35 88.13 97.68 87.06 108.06 87.84 88.38666667 94.32 752 907 731 656 796.6666667 0.047129533 0.267488408 03020///RNA polymerase+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005730///nucleolus" GO:0001055///RNA polymerase II activity+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030275///LRR domain binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity "GO:0001193///maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006379///mRNA cleavage" 20024 20024 'Sub1' mRNA 2771 2740 2781 45.52 44.28 48.45 42.96 45.92 42.91 46.08333333 43.93 3010 3143 2912 2764 3021.666667 0.142362743 0.116127772 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0033613///activating transcription factor binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032508///DNA duplex unwinding+++GO:0051053///negative regulation of DNA metabolic process+++GO:0051260///protein homooligomerization+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060395///SMAD protein signal transduction" 20042 20042 'Rps12' mRNA 833.99 846 902.85 132.49 134.89 152.48 216.24 210.62 241.16 139.9533333 222.6733333 1543.14 1460.7 1658.3 860.9466667 1554.046667 2.40E-19 0.838583672 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0043231///intracellular membrane-bounded organelle GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 20044 20044 'Rps14' mRNA 4662 4587 4716 598.56 586.5 642.73 686.48 764.84 696.73 609.2633333 716.0166667 6099 6604 5965 4655 6222.666667 6.03E-09 0.406278575 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0070181///small ribosomal subunit rRNA binding "GO:0000028///ribosomal small subunit assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0030218///erythrocyte differentiation+++GO:0030490///maturation of SSU-rRNA" 20054 20054 'Rps15' mRNA 2411 2318 2319 378.34 363.64 386.9 486.47 507.13 490.42 376.2933333 494.6733333 3516 3570 3421 2349.333333 3502.333333 7.86E-18 0.564058255 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0000028///ribosomal small subunit assembly+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0042274///ribosomal small subunit biogenesis+++GO:0097421///liver regeneration+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity 20055 20055 'Rps16' mRNA 2527 2495 2349 310.47 305.09 306.34 432.25 455.73 465.1 307.3 451.0266667 4015 4115 4164 2457 4098 1.17E-32 0.727413414 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0042274///ribosomal small subunit biogenesis+++GO:0097421///liver regeneration+++GO:1990830///cellular response to leukemia inhibitory factor" 20068 20068 'Rps17' mRNA 2023 2025 2211 375.05 376.16 435.29 479.83 537.71 533.95 395.5 517.1633333 2939 3193 3144 2086.333333 3092 3.78E-11 0.5537273 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0034101///erythrocyte homeostasis+++GO:0042274///ribosomal small subunit biogenesis 20084 20084 'Rps18' mRNA 2235 2048 2032.01 326.1 298.15 314.75 414.75 455.98 423.28 313 431.3366667 3238 3457 3182 2105.003333 3292.333333 1.65E-18 0.634330457 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0019843///rRNA binding+++GO:0019901///protein kinase binding GO:0006412///translation 20085 20085 'Rps19' mRNA 3925.58 3773.88 4010.83 557.52 534.2 604.68 778.61 936.91 829.68 565.4666667 848.4 6258.9 7319.42 6427.94 3903.43 6668.753333 1.41E-21 0.760470063 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0017134///fibroblast growth factor binding+++GO:0019901///protein kinase binding+++GO:0031369///translation initiation factor binding+++GO:0042802///identical protein binding "GO:0000028///ribosomal small subunit assembly+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002548///monocyte chemotaxis+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0007000///nucleolus organization+++GO:0007219///Notch signaling pathway+++GO:0030218///erythrocyte differentiation+++GO:0030490///maturation of SSU-rRNA+++GO:0031640///killing of cells of other organism+++GO:0042274///ribosomal small subunit biogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0060265///positive regulation of respiratory burst involved in inflammatory response+++GO:0060266///negative regulation of respiratory burst involved in inflammatory response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide" 20088 20088 'Rps24' mRNA 1746.93 1772.95 2068.11 104.79 102.12 134.54 188.92 197.64 193.26 113.8166667 193.2733333 2997.95 3196.96 3091.9 1862.663333 3095.603333 1.38E-14 0.71696716 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0031369///translation initiation factor binding GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0034101///erythrocyte homeostasis+++GO:0042274///ribosomal small subunit biogenesis 20090 20090 'Rps29' mRNA 1356 1348 1834 359.48 360.83 516.94 391.68 379.48 467.95 412.4166667 413.0366667 1667 1562 1910 1512.666667 1713 0.29574415 0.158480649 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane GO:0003735///structural constituent of ribosome+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0043065///positive regulation of apoptotic process 20091 20091 'Rps3a1' mRNA 5067 4870 4604 348.72 331.63 336.22 460.77 424.41 461.3 338.8566667 448.8266667 7673 6887 7422 4847 7327.333333 9.34E-26 0.584447572 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0031369///translation initiation factor binding+++GO:0048027///mRNA 5'-UTR binding GO:0006412///translation+++GO:0030154///cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045727///positive regulation of translation+++GO:0048146///positive regulation of fibroblast proliferation 20102 20102 'Rps4x' mRNA 4178 4185 4272 275.8 273.64 299.9 382.17 348.65 374.04 283.1133333 368.2866667 6620 5886 6264 4211.666667 6256.666667 1.45E-18 0.556831151 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0006412///translation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0045727///positive regulation of translation 20103 20103 'Rps5' mRNA 2628 2697 2395 248.18 252.87 240.08 344.96 321.41 321.11 247.0433333 329.16 4180 3790 3760 2573.333333 3910 5.35E-22 0.592597499 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0006450///regulation of translational fidelity 20104 20104 'Rps6' mRNA 7893 7660 7634.99 338.48 324.12 347.37 398 389.47 399.34 336.6566667 395.6033333 10658 10175 10343.86 7729.33 10392.28667 5.76E-15 0.414465886 01521///EGFR tyrosine kinase inhibitor resistance+++03010///Ribosome+++04066///HIF-1 signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++04910///Insulin signaling pathway+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0001890///placenta development+++GO:0002309///T cell proliferation involved in immune response+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0006924///activation-induced cell death of T cells+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007369///gastrulation+++GO:0008284///positive regulation of cell proliferation+++GO:0022605///mammalian oogenesis stage+++GO:0031929///TOR signaling+++GO:0033077///T cell differentiation in thymus+++GO:0042274///ribosomal small subunit biogenesis+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0048821///erythrocyte development 20111 20111 'Rps6ka1' mRNA 764 725 431 13.72 12.79 8.36 15.16 14.24 15.4 11.62333333 14.93333333 957 880 944 640 927 3.74E-04 0.533070638 04010///MAPK signaling pathway+++04114///Oocyte meiosis+++04150///mTOR signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04931///Insulin resistance+++05135///Yersinia infection+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005840///ribosome GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process "GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072574///hepatocyte proliferation+++GO:2000491///positive regulation of hepatic stellate cell activation" 20112 20112 'Rps6ka2' mRNA 731 881 428 7.2 8.53 4.58 2.9 3.96 4.53 6.77 3.796666667 331 449 513 680 431 0.079720328 -0.651336111 04010///MAPK signaling pathway+++04114///Oocyte meiosis+++04150///mTOR signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04931///Insulin resistance+++05135///Yersinia infection+++05207///Chemical carcinogenesis - receptor activation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005840///ribosome+++GO:0072687///meiotic spindle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001556///oocyte maturation+++GO:0002035///brain renin-angiotensin system+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0045786///negative regulation of cell cycle+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0060047///heart contraction+++GO:0070613///regulation of protein processing+++GO:0071322///cellular response to carbohydrate stimulus 20115 20115 'Rps7' mRNA 3029 2804 2714 203.55 186.41 193.52 244.3 246.41 253.63 194.4933333 248.1133333 4167 4096 4180 2849 4147.666667 9.27E-18 0.530728556 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005856///cytoskeleton+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0032040///small-subunit processome+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003730///mRNA 3'-UTR binding+++GO:0003735///structural constituent of ribosome+++GO:0008266///poly(U) RNA binding+++GO:0019901///protein kinase binding+++GO:0048027///mRNA 5'-UTR binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0001843///neural tube closure+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0042274///ribosomal small subunit biogenesis+++GO:0050821///protein stabilization+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 20116 20116 'Rps8' mRNA 2617.17 2553.73 2454.53 247.49 239.62 246.34 335.56 346.64 339.94 244.4833333 340.7133333 4058.52 4080.74 3967.96 2541.81 4035.74 1.51E-27 0.655714838 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:1990904///ribonucleoprotein complex GO:0003735///structural constituent of ribosome "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006412///translation" 20128 20128 'Trim30a' mRNA 175.04 219.49 220.67 2.5 3.08 3.36 19.69 17.6 20.18 2.98 19.15666667 1582.81 1380.01 1570.92 205.0666667 1511.246667 9.21E-137 2.869689829 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990462///omegasome "GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000209///protein polyubiquitination+++GO:0002218///activation of innate immune response+++GO:0006914///autophagy+++GO:0009617///response to bacterium+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032880///regulation of protein localization+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1902187///negative regulation of viral release from host cell+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 20130 20130 'Rras' mRNA 119 109 85 8.18 7.17 6.34 14.36 15.95 16.93 7.23 15.74666667 252 269 274 104.3333333 265 2.10E-12 1.338181129 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04218///Cellular senescence+++04360///Axon guidance+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05132///Salmonella infection+++05205///Proteoglycans in cancer GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding GO:0002521///leukocyte differentiation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0030336///negative regulation of cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0051896///regulation of protein kinase B signaling+++GO:0060325///face morphogenesis+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin+++GO:2001214///positive regulation of vasculogenesis 20132 20132 'Rrh' mRNA 4 6 2 0.1 0.16 0.09 0 0.08 0.14 0.116666667 0.073333333 0 2 4 4 2 0.602996324 -0.984837803 GO:0001750///photoreceptor outer segment+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009584///detection of visible light+++GO:0018298///protein-chromophore linkage+++GO:0050896///response to stimulus+++GO:0071482///cellular response to light stimulus 20133 20133 'Rrm1' mRNA 681 765 703 9.2 10.16 10.07 16.18 14.71 16.57 9.81 15.82 1379 1225 1368 716.3333333 1324 8.66E-22 0.873987956 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00480///Glutathione metabolism+++00983///Drug metabolism - other enzymes GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005971///ribonucleoside-diphosphate reductase complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004748///ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016491///oxidoreductase activity+++GO:0017076///purine nucleotide binding+++GO:0042802///identical protein binding+++GO:0061731///ribonucleoside-diphosphate reductase activity+++GO:0097718///disordered domain specific binding" GO:0000278///mitotic cell cycle+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006260///DNA replication+++GO:0008152///metabolic process+++GO:0008584///male gonad development+++GO:0009263///deoxyribonucleotide biosynthetic process+++GO:0010212///response to ionizing radiation+++GO:0021846///cell proliferation in forebrain+++GO:0051290///protein heterotetramerization+++GO:0060041///retina development in camera-type eye 20135 20135 'Rrm2' mRNA 21 34 24 0.54 0.87 0.66 11.32 13.72 12.49 0.69 12.51 503 595 537 26.33333333 545 2.95E-87 4.36322531 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00480///Glutathione metabolism+++00983///Drug metabolism - other enzymes+++04115///p53 signaling pathway GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005971///ribonucleoside-diphosphate reductase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004748///ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor+++GO:0005515///protein binding+++GO:0008199///ferric iron binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" GO:0001824///blastocyst development+++GO:0006260///DNA replication+++GO:0008284///positive regulation of cell proliferation+++GO:0009262///deoxyribonucleotide metabolic process+++GO:0009263///deoxyribonucleotide biosynthetic process+++GO:0051290///protein heterotetramerization 20147 20147 'Rs1' mRNA 8 5 14 0.05 0.03 0.1 0.02 0.01 0.03 0.06 0.02 3 1 5 9 3 0.172055787 -1.619607686 GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0098984///neuron to neuron synapse "GO:0001786///phosphatidylserine binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0031210///phosphatidylcholine binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0010842///retina layer formation+++GO:0016062///adaptation of rhodopsin mediated signaling+++GO:0050896///response to stimulus+++GO:0051260///protein homooligomerization 20148 20148 'Dhrs3' mRNA 5130.09 4906 4924.46 125.69 119.12 128.83 133.62 137.35 132.87 124.5466667 134.6133333 6371.68 6262.53 6011 4986.85 6215.07 3.26E-07 0.305121993 00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0052650///NADP-retinol dehydrogenase activity" GO:0001523///retinoid metabolic process+++GO:0003151///outflow tract morphogenesis+++GO:0030278///regulation of ossification+++GO:0042572///retinol metabolic process+++GO:0048385///regulation of retinoic acid receptor signaling pathway+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0060021///roof of mouth development+++GO:0060349///bone morphogenesis+++GO:0060411///cardiac septum morphogenesis 20163 20163 'Rsu1' mRNA 1069 1123 1048 39.37 40.78 40.96 53.02 54.08 51.13 40.37 52.74333333 1654 1646 1543 1080 1614.333333 7.15E-13 0.568559624 GO:0005925///focal adhesion GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0043547///positive regulation of GTPase activity+++GO:2000179///positive regulation of neural precursor cell proliferation 20166 20166 'Rtkn' mRNA 2377 2239 2171 51.77 48.3 50.6 62.55 64.02 60.79 50.22333333 62.45333333 3160 3125 2932 2262.333333 3072.333333 1.64E-10 0.43009192 GO:0005826///actomyosin contractile ring+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005095///GTPase inhibitor activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031267///small GTPase binding GO:0000281///mitotic cytokinesis+++GO:0000915///actomyosin contractile ring assembly+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0031106///septin ring organization+++GO:0032185///septin cytoskeleton organization+++GO:0042981///regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity 20167 20167 'Rtn2' mRNA 141 134 144 6.35 6.46 7.3 3.6 3.91 3.89 6.703333333 3.8 74 78 77 139.6666667 76.33333333 2.48E-04 -0.884703181 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014802///terminal cisterna+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042383///sarcolemma GO:0003674///molecular_function GO:0010467///gene expression+++GO:0015031///protein transport+++GO:0046324///regulation of glucose import+++GO:0065002///intracellular protein transmembrane transport+++GO:1902430///negative regulation of amyloid-beta formation 20168 20168 'Rtn3' mRNA 8510 8654 8175 162.41 162.66 165.53 165.99 162.61 160.62 163.5333333 163.0733333 9973 9547 9344 8446.333333 9621.333333 7.41E-04 0.176112962 05010///Alzheimer disease GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0016192///vesicle-mediated transport+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:1902430///negative regulation of amyloid-beta formation 20170 20170 'Hps6' mRNA 241 252 259 4.95 5.09 5.64 7.14 7.55 6.6 5.226666667 7.096666667 400 413 358 250.6666667 390.3333333 2.68E-05 0.625930344 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031084///BLOC-2 complex+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding GO:0006996///organelle organization+++GO:0007596///blood coagulation+++GO:0009306///protein secretion+++GO:0030318///melanocyte differentiation+++GO:0032418///lysosome localization+++GO:0043473///pigmentation+++GO:0055088///lipid homeostasis+++GO:0072657///protein localization to membrane 20174 20174 'Ruvbl2' mRNA 995.56 1024.06 976.42 34.3 34.63 35.71 32.32 36.89 34.93 34.88 34.71333333 1074.11 1196.87 1130.47 998.68 1133.816667 0.084905132 0.172390929 GO:0000791///euchromatin+++GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031011///Ino80 complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0071339///MLL1 complex+++GO:0097255///R2TP complex+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0003678///DNA helicase activity+++GO:0003714///transcription corepressor activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0016787///hydrolase activity+++GO:0017025///TBP-class protein binding+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043139///5'-3' DNA helicase activity+++GO:0043531///ADP binding+++GO:0051117///ATPase binding "GO:0000492///box C/D snoRNP assembly+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016573///histone acetylation+++GO:0032508///DNA duplex unwinding+++GO:0034644///cellular response to UV+++GO:0035066///positive regulation of histone acetylation+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071169///establishment of protein localization to chromatin+++GO:0071392///cellular response to estradiol stimulus+++GO:0071733///transcriptional activation by promoter-enhancer looping+++GO:0071899///negative regulation of estrogen receptor binding+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 20181 20181 'Rxra' mRNA 1024 1096 1054 11.44 12.07 12.55 6.78 7.22 6.57 12.02 6.856666667 697 728 654 1058 693 1.37E-10 -0.622305421 "03320///PPAR signaling pathway+++04151///PI3K-Akt signaling pathway+++04659///Th17 cell differentiation+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04932///Non-alcoholic fatty liver disease+++04976///Bile secretion+++05160///Hepatitis C+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05207///Chemical carcinogenesis - receptor activation+++05216///Thyroid cancer+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05226///Gastric cancer+++05417///Lipid and atherosclerosis" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030424///axon+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001972///retinoic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0050692///DBD domain binding+++GO:0050693///LBD domain binding+++GO:0070644///vitamin D response element binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0001893///maternal placenta development+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0007566///embryo implantation+++GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0030154///cell differentiation+++GO:0031641///regulation of myelination+++GO:0032526///response to retinoic acid+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045994///positive regulation of translational initiation by iron+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048856///anatomical structure development+++GO:0051384///response to glucocorticoid+++GO:0055007///cardiac muscle cell differentiation+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060038///cardiac muscle cell proliferation+++GO:0060485///mesenchyme development+++GO:0060528///secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development+++GO:0060687///regulation of branching involved in prostate gland morphogenesis+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0061032///visceral serous pericardium development+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" 20182 20182 'Rxrb' mRNA 451 445 391 10.74 10.41 9.85 10.15 10.08 10.67 10.33333333 10.3 491 475 498 429 488 0.188301211 0.176182307 "03320///PPAR signaling pathway+++04659///Th17 cell differentiation+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05207///Chemical carcinogenesis - receptor activation+++05216///Thyroid cancer+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05226///Gastric cancer+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0042802///identical protein binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046966///thyroid hormone receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0001893///maternal placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0031641///regulation of myelination+++GO:0032526///response to retinoic acid+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048856///anatomical structure development+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060038///cardiac muscle cell proliferation+++GO:0071300///cellular response to retinoic acid" 20183 20183 'Rxrg' mRNA 42 48 41 1.11 1.4 1.17 0.55 0.67 0.39 1.226666667 0.536666667 23 24 13 43.66666667 20 0.015366252 -1.137049228 "03320///PPAR signaling pathway+++04659///Th17 cell differentiation+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05207///Chemical carcinogenesis - receptor activation+++05216///Thyroid cancer+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05226///Gastric cancer+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0031641///regulation of myelination+++GO:0032526///response to retinoic acid+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048856///anatomical structure development+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus" 20184 20184 'Uimc1' mRNA 811.36 721.31 777.14 17.81 15.66 17.95 15.35 14.95 13.2 17.14 14.5 800.99 740.7 653.46 769.9366667 731.7166667 0.526764221 -0.08847529 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0070531///BRCA1-A complex GO:0003677///DNA binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding "GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010212///response to ionizing radiation+++GO:0045739///positive regulation of DNA repair+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint" 20185 20185 'Ncor1' mRNA 1848.52 1986.62 1733.2 12.97 13.38 12.76 12.07 9.8 11.37 13.03666667 11.08 1988.35 1591.56 1821.6 1856.113333 1800.503333 0.603737775 -0.055727185 01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway+++05202///Transcriptional misregulation in cancer GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016580///Sin3 complex+++GO:0017053///transcriptional repressor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0035033///histone deacetylase regulator activity+++GO:0035257///nuclear hormone receptor binding+++GO:0042826///histone deacetylase binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0002361///CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0021794///thalamus development+++GO:0031065///positive regulation of histone deacetylation+++GO:0032922///circadian regulation of gene expression+++GO:0040014///regulation of multicellular organism growth+++GO:0042632///cholesterol homeostasis+++GO:0045475///locomotor rhythm+++GO:0045820///negative regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045922///negative regulation of fatty acid metabolic process+++GO:0046329///negative regulation of JNK cascade+++GO:0048511///rhythmic process+++GO:0051225///spindle assembly+++GO:0060318///definitive erythrocyte differentiation+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1904017///cellular response to Thyroglobulin triiodothyronine" 20186 20186 'Nr1h4' mRNA 5 7 3 0.14 0.19 0.1 0.43 0.2 0.08 0.143333333 0.236666667 18 8 3 5 9.666666667 0.419593725 0.940639174 04976///Bile secretion GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0043235///receptor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0032052///bile acid binding+++GO:0038181///bile acid receptor activity+++GO:0042277///peptide binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:1902122///chenodeoxycholic acid binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001080///nitrogen catabolite activation of transcription from RNA polymerase II promoter+++GO:0001678///cellular glucose homeostasis+++GO:0002376///immune system process+++GO:0006109///regulation of carbohydrate metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0007043///cell-cell junction assembly+++GO:0007219///Notch signaling pathway+++GO:0008206///bile acid metabolic process+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010868///negative regulation of triglyceride biosynthetic process+++GO:0010903///negative regulation of very-low-density lipoprotein particle remodeling+++GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0015721///bile acid and bile salt transport+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0034255///regulation of urea metabolic process+++GO:0034971///histone H3-R17 methylation+++GO:0035356///cellular triglyceride homeostasis+++GO:0035690///cellular response to drug+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0038183///bile acid signaling pathway+++GO:0038185///intracellular bile acid receptor signaling pathway+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0050728///negative regulation of inflammatory response+++GO:0055089///fatty acid homeostasis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070328///triglyceride homeostasis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071398///cellular response to fatty acid+++GO:0071417///cellular response to organonitrogen compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0071873///response to norepinephrine+++GO:1903413///cellular response to bile acid+++GO:1904179///positive regulation of adipose tissue development+++GO:1905695///positive regulation of phosphatidic acid biosynthetic process+++GO:2000213///positive regulation of glutamate metabolic process+++GO:2001250///positive regulation of ammonia assimilation cycle" 20187 20187 'Ryk' mRNA 401 403 365 6.71 6.69 6.51 6.21 5.63 6.46 6.636666667 6.1 427 376 430 389.6666667 411 0.704562229 0.065805683 04310///Wnt signaling pathway+++04360///Axon guidance GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017147///Wnt-protein binding+++GO:0042813///Wnt-activated receptor activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0022038///corpus callosum development+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0033674///positive regulation of kinase activity+++GO:0036518///chemorepulsion of dopaminergic neuron axon+++GO:0043410///positive regulation of MAPK cascade+++GO:0048705///skeletal system morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0061643///chemorepulsion of axon+++GO:0071679///commissural neuron axon guidance+++GO:1904938///planar cell polarity pathway involved in axon guidance+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1904953///Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 20190 20190 'Ryr1' mRNA 1 1 4 0 0 0.01 0.06 0.06 0.04 0.003333333 0.053333333 21 19 14 2 18 0.001216737 3.141324108 04020///Calcium signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014802///terminal cisterna+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030314///junctional membrane complex+++GO:0030315///T-tubule+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031301///integral component of organelle membrane+++GO:0031674///I band+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034704///calcium channel complex+++GO:0042383///sarcolemma+++GO:1990425///ryanodine receptor complex GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0005216///ion channel activity+++GO:0005219///ryanodine-sensitive calcium-release channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0048763///calcium-induced calcium release activity GO:0001666///response to hypoxia+++GO:0003151///outflow tract morphogenesis+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0007275///multicellular organism development+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0031000///response to caffeine+++GO:0043588///skin development+++GO:0043931///ossification involved in bone maturation+++GO:0048741///skeletal muscle fiber development+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051289///protein homotetramerization+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071313///cellular response to caffeine+++GO:0071318///cellular response to ATP 20191 20191 'Ryr2' mRNA 160 151 133 0.66 0.57 0.62 0.03 0.06 0 0.616666667 0.03 6 14 1 148 7 1.42E-24 -4.409054981 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04911///Insulin secretion+++04921///Oxytocin signaling pathway+++04972///Pancreatic secretion+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031672///A band+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034704///calcium channel complex+++GO:0042383///sarcolemma+++GO:0043005///neuron projection GO:0005216///ion channel activity+++GO:0005219///ryanodine-sensitive calcium-release channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015278///calcium-release channel activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0043924///suramin binding+++GO:0048763///calcium-induced calcium release activity+++GO:0097110///scaffold protein binding+++GO:0097159///organic cyclic compound binding GO:0001666///response to hypoxia+++GO:0002027///regulation of heart rate+++GO:0003143///embryonic heart tube morphogenesis+++GO:0003220///left ventricular cardiac muscle tissue morphogenesis+++GO:0003300///cardiac muscle hypertrophy+++GO:0005513///detection of calcium ion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007275///multicellular organism development+++GO:0010460///positive regulation of heart rate+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014850///response to muscle activity+++GO:0019722///calcium-mediated signaling+++GO:0031000///response to caffeine+++GO:0032026///response to magnesium ion+++GO:0034220///ion transmembrane transport+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035994///response to muscle stretch+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051592///response to calcium ion+++GO:0051775///response to redox state+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060048///cardiac muscle contraction+++GO:0060401///cytosolic calcium ion transport+++GO:0060402///calcium ion transport into cytosol+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071313///cellular response to caffeine+++GO:0071421///manganese ion transmembrane transport+++GO:0071872///cellular response to epinephrine stimulus+++GO:0072599///establishment of protein localization to endoplasmic reticulum+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086029///Purkinje myocyte to ventricular cardiac muscle cell signaling+++GO:0097050///type B pancreatic cell apoptotic process+++GO:0098735///positive regulation of the force of heart contraction+++GO:0098904///regulation of AV node cell action potential+++GO:0098907///regulation of SA node cell action potential+++GO:0098910///regulation of atrial cardiac muscle cell action potential+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:1901896///positive regulation of calcium-transporting ATPase activity 20192 20192 'Ryr3' mRNA 103 108 90 0.34 0.35 0.32 0.38 0.46 0.49 0.336666667 0.443333333 132 154 163 100.3333333 149.6666667 0.015812412 0.569420065 04020///Calcium signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04921///Oxytocin signaling pathway+++04970///Salivary secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030314///junctional membrane complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034704///calcium channel complex+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005216///ion channel activity+++GO:0005219///ryanodine-sensitive calcium-release channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0015278///calcium-release channel activity+++GO:0048763///calcium-induced calcium release activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006941///striated muscle contraction+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051289///protein homotetramerization+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071286///cellular response to magnesium ion+++GO:0071313///cellular response to caffeine+++GO:0071318///cellular response to ATP 20193 20193 'S100a1' mRNA 32975 31691 32815 4051.29 3875.16 4279.44 2096.02 2204.9 2142.86 4068.63 2147.926667 19469 19909 19185 32493.66667 19521 1.41E-39 -0.748177288 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0031672///A band+++GO:0031674///I band+++GO:0043005///neuron projection GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0051117///ATPase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008016///regulation of heart contraction+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1903672///positive regulation of sprouting angiogenesis 20194 20194 'S100a10' mRNA 1889 1791 1828 214.14 201.87 219.95 685.61 798.68 716.15 211.9866667 733.48 6907 7825 6957 1836 7229.666667 2.87E-157 1.966074082 05132///Salmonella infection GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0045121///membrane raft+++GO:0062023///collagen-containing extracellular matrix+++GO:1990665///AnxA2-p11 complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0048306///calcium-dependent protein binding GO:0001765///membrane raft assembly+++GO:0006900///vesicle budding from membrane+++GO:0042493///response to drug+++GO:0043547///positive regulation of GTPase activity+++GO:0051099///positive regulation of binding+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0071229///cellular response to acid chemical+++GO:0072659///protein localization to plasma membrane+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 20195 20195 'S100a11' mRNA 3502.52 3183.09 3401.45 585.95 532.55 604.2 1306.53 1526.96 1388.53 574.2333333 1407.34 8881.14 10070.06 9080 3362.353333 9343.733333 1.03E-85 1.462547261 GO:0001726///ruffle+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0042379///chemokine receptor binding+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0032496///response to lipopolysaccharide+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042742///defense response to bacterium+++GO:0071624///positive regulation of granulocyte chemotaxis+++GO:0090026///positive regulation of monocyte chemotaxis 20196 20196 'S100a13' mRNA 973 878 979 94.77 85.34 100.78 75.8 87.97 84.41 93.63 82.72666667 881 1001 949 943.3333333 943.6666667 0.932088724 -0.012413113 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0017134///fibroblast growth factor binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050786///RAGE receptor binding GO:0001819///positive regulation of cytokine production+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046688///response to copper ion+++GO:0051602///response to electrical stimulus 20197 20197 'S100a3' mRNA 11 16 16 0.46 0.87 0.76 2.81 2.43 1.01 0.696666667 2.083333333 58 49 23 14.33333333 43.33333333 0.003070153 1.578620006 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding+++GO:0048306///calcium-dependent protein binding 20198 20198 'S100a4' mRNA 196 191 227 33.24 32.49 40.6 238.58 289.55 272.35 35.44333333 266.8266667 1595 1879 1752 204.6666667 1742 3.04E-149 3.076490299 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050786///RAGE receptor binding GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling 20200 20200 'S100a6' mRNA 530 534 552 52.14 52.14 57.63 182.22 200.33 199.01 53.97 193.8533333 2118 2266 2232 538.6666667 2205.333333 4.49E-119 2.021497099 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005523///tropomyosin binding+++GO:0008270///zinc ion binding+++GO:0015075///ion transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0034220///ion transmembrane transport 20201 20201 'S100a8' mRNA 406 408 457 106.55 108.09 127.51 126.51 151.96 132.88 114.05 137.1166667 544 632 548 423.6666667 574.6666667 0.002009526 0.426106288 04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045111///intermediate filament cytoskeleton GO:0005509///calcium ion binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0016209///antioxidant activity+++GO:0035662///Toll-like receptor 4 binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050544///arachidonic acid binding+++GO:0050786///RAGE receptor binding GO:0002376///immune system process+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002793///positive regulation of peptide secretion+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0014002///astrocyte development+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0030593///neutrophil chemotaxis+++GO:0032496///response to lipopolysaccharide+++GO:0035425///autocrine signaling+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0070488///neutrophil aggregation+++GO:0098869///cellular oxidant detoxification+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 20202 20202 'S100a9' mRNA 351 382 361 55.23 59.98 60.35 71.04 70.02 71.8 58.52 70.95333333 514 492 500 364.6666667 502 3.52E-04 0.449111644 04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction GO:0005509///calcium ion binding+++GO:0016209///antioxidant activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0002376///immune system process+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0002793///positive regulation of peptide secretion+++GO:0006417///regulation of translation+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0010976///positive regulation of neuron projection development+++GO:0014002///astrocyte development+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0030194///positive regulation of blood coagulation+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0031532///actin cytoskeleton reorganization+++GO:0032496///response to lipopolysaccharide+++GO:0035425///autocrine signaling+++GO:0035606///peptidyl-cysteine S-trans-nitrosylation+++GO:0035821///modification of morphology or physiology of other organism+++GO:0045087///innate immune response+++GO:0045113///regulation of integrin biosynthetic process+++GO:0050729///positive regulation of inflammatory response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070488///neutrophil aggregation+++GO:0098869///cellular oxidant detoxification+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 20203 20203 'S100b' mRNA 26736 27097 29463 937.38 936.62 1095.89 484.14 499.04 500.37 989.9633333 494.5166667 15867 15962 15868 27765.33333 15899 2.07E-34 -0.819399875 GO:0001726///ruffle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding+++GO:0046872///metal ion binding+++GO:0048156///tau protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0050786///RAGE receptor binding GO:0001817///regulation of cytokine production+++GO:0006112///energy reserve metabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0031643///positive regulation of myelination+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048708///astrocyte differentiation+++GO:0050806///positive regulation of synaptic transmission+++GO:0051384///response to glucocorticoid+++GO:0051597///response to methylmercury+++GO:0060291///long-term synaptic potentiation+++GO:0071456///cellular response to hypoxia+++GO:2001015///negative regulation of skeletal muscle cell differentiation 20204 20204 'Prrx2' mRNA 30 49 15 1.65 2.59 0.88 3.94 2.99 3.56 1.706666667 3.496666667 82 62 73 31.33333333 72.33333333 0.003463703 1.209408217 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030326///embryonic limb morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048844///artery morphogenesis+++GO:0051216///cartilage development" 20208 20208 'Saa1' mRNA 0 1 4 0 0.12 0.53 6.4 6.17 5.85 0.216666667 6.14 60 56 52 1.666666667 56 1.83E-10 5.049989308 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005881///cytoplasmic microtubule+++GO:0034364///high-density lipoprotein particle GO:0001664///G protein-coupled receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0006953///acute-phase response+++GO:0008203///cholesterol metabolic process+++GO:0009617///response to bacterium 20209 20209 'Saa2' mRNA 0 1 1 0 0.13 0.13 3.96 3.03 3.31 0.086666667 3.433333333 36 27 29 0.666666667 30.66666667 5.83E-06 5.508427307 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005881///cytoplasmic microtubule+++GO:0034364///high-density lipoprotein particle GO:0001664///G protein-coupled receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0001819///positive regulation of cytokine production+++GO:0006953///acute-phase response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008203///cholesterol metabolic process+++GO:0009617///response to bacterium+++GO:0035634///response to stilbenoid+++GO:0045785///positive regulation of cell adhesion+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis 20210 20210 'Saa3' mRNA 135 135 182 20.76 20.73 29.71 180.46 190.21 190.71 23.73333333 187.1266667 1336 1367 1359 150.6666667 1354 2.54E-131 3.151684591 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034364///high-density lipoprotein particle GO:0035662///Toll-like receptor 4 binding+++GO:0042056///chemoattractant activity GO:0006953///acute-phase response+++GO:0007252///I-kappaB phosphorylation+++GO:0009617///response to bacterium+++GO:0035634///response to stilbenoid+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0071347///cellular response to interleukin-1 20215 20215 'Sag' mRNA 37 23 18 1.25 0.58 0.56 0.49 0.13 0.22 0.796666667 0.28 12 6 11 26 9.666666667 0.027893394 -1.434785991 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0016020///membrane+++GO:0042995///cell projection GO:0001664///G protein-coupled receptor binding+++GO:0002046///opsin binding+++GO:0030507///spectrin binding+++GO:0051219///phosphoprotein binding GO:0002031///G protein-coupled receptor internalization+++GO:0007165///signal transduction 20216 20216 'Acsm3' mRNA 0 0 1.45 0 0 0.03 0.02 0.05 0 0.01 0.023333333 1.5 2.96 0 0.483333333 1.486666667 0.728867167 1.474605776 00650///Butanoate metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004321///fatty-acyl-CoA synthase activity+++GO:0005524///ATP binding+++GO:0015645///fatty acid ligase activity+++GO:0016874///ligase activity+++GO:0018729///propionate CoA-transferase activity+++GO:0031956///medium-chain fatty acid-CoA ligase activity+++GO:0043759///branched-chain acyl-CoA synthetase (ADP-forming) activity+++GO:0046872///metal ion binding+++GO:0047760///butyrate-CoA ligase activity+++GO:0050218///propionate-CoA ligase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006637///acyl-CoA metabolic process 20218 20218 'Khdrbs1' mRNA 1487 1465 474 21.48 20.82 7.26 7.14 11.64 10.65 16.52 9.81 569 906 822 1142 765.6666667 0.371859602 -0.560708158 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0070618///Grb2-Sos complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding+++GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding+++GO:0035591///signaling adaptor activity+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:1990782///protein tyrosine kinase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0007166///cell surface receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0045948///positive regulation of translational initiation+++GO:0046831///regulation of RNA export from nucleus+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0050852///T cell receptor signaling pathway" 20220 20220 'Sap18' mRNA 1243.6 1192.44 1272.95 19.57 18.46 21.25 15.08 14.92 15.49 19.76 15.16333333 1102.56 1065.95 1097.16 1236.33 1088.556667 0.039053467 -0.197416692 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0061574///ASAP complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 20222 20222 'Sf3a2' mRNA 902 908 490 31.35 31.11 18.07 19.29 18.13 15.78 26.84333333 17.73333333 638 585 505 766.6666667 576 0.020336211 -0.412550145 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010976///positive regulation of neuron projection development+++GO:1903241///U2-type prespliceosome assembly" 20224 20224 'Sar1a' mRNA 3521 3644 3475 73.7 74.93 77.15 89.6 87.24 87.3 75.26 88.04666667 4926 4684 4649 3546.666667 4753 1.13E-12 0.410221744 04141///Protein processing in endoplasmic reticulum+++05134///Legionellosis GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016529///sarcoplasmic reticulum+++GO:0030127///COPII vesicle coat+++GO:0070971///endoplasmic reticulum exit site GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0003400///regulation of COPII vesicle coating+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016050///vesicle organization+++GO:0016192///vesicle-mediated transport+++GO:0061024///membrane organization+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:1901301///regulation of cargo loading into COPII-coated vesicle+++GO:1901303///negative regulation of cargo loading into COPII-coated vesicle 20226 20226 'Sars' mRNA 2016 2019 2025 30.09 29.64 32.04 33.78 31.31 33.48 30.59 32.85666667 2605 2360 2502 2020 2489 6.72E-05 0.287862569 00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004828///serine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006434///seryl-tRNA aminoacylation+++GO:0016525///negative regulation of angiogenesis+++GO:0097056///selenocysteinyl-tRNA(Sec) biosynthetic process+++GO:1904046///negative regulation of vascular endothelial growth factor production 20227 20227 'Sart1' mRNA 909 786 306 9.53 8.1 3.4 2.91 3.19 3.85 7.01 3.316666667 319 342 410 667 357 0.070972761 -0.891780775 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005794///Golgi apparatus+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome "GO:0000398///mRNA splicing, via spliceosome+++GO:0000481///maturation of 5S rRNA+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0045585///positive regulation of cytotoxic T cell differentiation" 20229 20229 'Sat1' mRNA 6245 6140 6010 322.45 312.91 329.39 587.36 611.03 599.17 321.5833333 599.1866667 12930 13083 12748 6131.666667 12920.33333 4.57E-92 1.063536391 00330///Arginine and proline metabolism+++04216///Ferroptosis GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004145///diamine N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019809///spermidine binding+++GO:0042802///identical protein binding" GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0006598///polyamine catabolic process+++GO:0009447///putrescine catabolic process+++GO:0032918///spermidine acetylation+++GO:0042127///regulation of cell proliferation+++GO:0046208///spermine catabolic process 20230 20230 'Satb1' mRNA 360 334 309 3.68 3.37 3.42 1.82 1.52 1.69 3.49 1.676666667 193 160 171 334.3333333 174.6666667 2.48E-09 -0.948169644 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0016605///PML body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008544///epidermis development+++GO:0016571///histone methylation+++GO:0042110///T cell activation+++GO:0043367///CD4-positive, alpha-beta T cell differentiation+++GO:0043374///CD8-positive, alpha-beta T cell differentiation+++GO:0050798///activated T cell proliferation+++GO:0060004///reflex" 20238 20238 'Atxn1' mRNA 3570 3617 3080 14.8 14.95 13.67 7.09 6.1 6.22 14.47333333 6.47 1962 1644 1718 3422.333333 1774.666667 2.34E-40 -0.957850767 04330///Notch signaling pathway+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0042405///nuclear inclusion body+++GO:0098794///postsynapse GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008266///poly(U) RNA binding+++GO:0034046///poly(G) binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007612///learning+++GO:0007613///memory+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0035176///social behavior+++GO:0042326///negative regulation of phosphorylation+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048856///anatomical structure development+++GO:0051168///nuclear export+++GO:0060079///excitatory postsynaptic potential+++GO:0060252///positive regulation of glial cell proliferation" 20239 20239 'Atxn2' mRNA 1121.72 1034.6 868.77 12.7 11.12 9.87 10.07 9.12 10.34 11.23 9.843333333 1071.23 966.45 1050.58 1008.363333 1029.42 0.863090843 0.021526515 04711///Circadian rhythm - fly+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0008022///protein C-terminus binding+++GO:0050692///DBD domain binding GO:0002091///negative regulation of receptor internalization+++GO:0010603///regulation of cytoplasmic mRNA processing body assembly+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly+++GO:0040015///negative regulation of multicellular organism growth+++GO:0048812///neuron projection morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050905///neuromuscular process 20249 20249 'Scd1' mRNA 3141.63 3365.2 3324.31 34.75 36.6 39 49.2 45.35 44.84 36.78333333 46.46333333 5120.7 4611.39 4520.61 3277.046667 4750.9 2.74E-14 0.521795016 01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04212///Longevity regulating pathway - worm+++04936///Alcoholic liver disease GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0032896///palmitoyl-CoA 9-desaturase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0006641///triglyceride metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0009617///response to bacterium+++GO:0010873///positive regulation of cholesterol esterification+++GO:0033561///regulation of water loss via skin+++GO:0034434///sterol esterification+++GO:0034435///cholesterol esterification+++GO:0048733///sebaceous gland development+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0055088///lipid homeostasis+++GO:0070542///response to fatty acid+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903699///tarsal gland development+++GO:1903966///monounsaturated fatty acid biosynthetic process 20250 20250 'Scd2' mRNA 25240.08 24971.26 25342.02 246.44 239.72 262.46 191.74 165.35 177.98 249.54 178.3566667 22608.87 19049.91 20329.31 25184.45333 20662.69667 1.87E-06 -0.300287984 01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04212///Longevity regulating pathway - worm+++04936///Alcoholic liver disease GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0032896///palmitoyl-CoA 9-desaturase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0070542///response to fatty acid+++GO:1903966///monounsaturated fatty acid biosynthetic process 20254 20254 'Scg2' mRNA 7 2 7 0.15 0.04 0.16 0.3 0.09 0.13 0.116666667 0.173333333 16 5 7 5.333333333 9.333333333 0.511591187 0.773402932 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule+++GO:0031045///dense core granule+++GO:0098992///neuronal dense core vesicle GO:0005125///cytokine activity+++GO:0042056///chemoattractant activity GO:0000165///MAPK cascade+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0035556///intracellular signal transduction+++GO:0048245///eosinophil chemotaxis+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 20255 20255 'Scg3' mRNA 675 579 633 17.2 14.57 17.12 1.44 1.94 1.54 16.29666667 1.64 65 85 70 629 73.33333333 1.31E-77 -3.112656618 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0033366///protein localization to secretory granule 20256 20256 'Clec11a' mRNA 183 161 140 5.34 4.63 4.33 3.12 2.34 3.04 4.766666667 2.833333333 123 90 116 161.3333333 109.6666667 0.014685675 -0.567420021 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0008083///growth factor activity+++GO:0030246///carbohydrate binding GO:0001503///ossification+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation 20257 20257 'Stmn2' mRNA 10 7 10 0.3 0.21 0.32 0.18 0.54 0.22 0.276666667 0.313333333 7 20 8 9 11.66666667 0.735576964 0.365993952 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0048306///calcium-dependent protein binding GO:0007019///microtubule depolymerization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0031175///neuron projection development+++GO:1990090///cellular response to nerve growth factor stimulus 20259 20259 'Scin' mRNA 338 423 430 6.19 7.67 8.41 7.74 6.8 7.23 7.423333333 7.256666667 481 415 440 397 445.3333333 0.379089419 0.149975352 04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05203///Viral carcinogenesis GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding" GO:0007417///central nervous system development+++GO:0008154///actin polymerization or depolymerization+++GO:0008285///negative regulation of cell proliferation+++GO:0030031///cell projection assembly+++GO:0032330///regulation of chondrocyte differentiation+++GO:0042989///sequestering of actin monomers+++GO:0043065///positive regulation of apoptotic process+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051127///positive regulation of actin nucleation+++GO:0051693///actin filament capping 20262 20262 'Stmn3' mRNA 446 463 413 24.38 25.01 23.96 6.72 5.96 5.91 24.45 6.196666667 141 122 120 440.6666667 127.6666667 3.56E-32 -1.798564787 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0015631///tubulin binding+++GO:0019904///protein domain specific binding GO:0001835///blastocyst hatching+++GO:0007019///microtubule depolymerization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031175///neuron projection development+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0051493///regulation of cytoskeleton organization 20264 20264 'Scn10a' mRNA 0 2 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0044299///C-fiber+++GO:0071439///clathrin complex+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0044325///ion channel binding GO:0002027///regulation of heart rate+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0061337///cardiac conduction+++GO:0086010///membrane depolarization during action potential+++GO:0086016///AV node cell action potential+++GO:0086043///bundle of His cell action potential+++GO:0098655///cation transmembrane transport 20265 20265 'Scn1a' mRNA 1 0 3 0.01 0 0.02 0.01 0.01 0.01 0.01 0.01 2 2 2 1.333333333 2 0.846191721 0.536112273 04728///Dopaminergic synapse GO:0001518///voltage-gated sodium channel complex+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0033268///node of Ranvier+++GO:0034706///sodium channel complex+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0031402///sodium ion binding GO:0001508///action potential+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007628///adult walking behavior+++GO:0019227///neuronal action potential propagation+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050884///neuromuscular process controlling posture+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0055085///transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 20266 20266 'Scn1b' mRNA 161 144 163 5.92 5.24 6.4 10.24 12.08 12.97 5.853333333 11.76333333 319 365 390 156 358 2.75E-12 1.186198972 04261///Adrenergic signaling in cardiomyocytes GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0033268///node of Ranvier+++GO:0034706///sodium channel complex+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0017080///sodium channel regulator activity+++GO:0019871///sodium channel inhibitor activity+++GO:0044325///ion channel binding+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential+++GO:0086062///voltage-gated sodium channel activity involved in Purkinje myocyte action potential GO:0002028///regulation of sodium ion transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007411///axon guidance+++GO:0010765///positive regulation of sodium ion transport+++GO:0010976///positive regulation of neuron projection development+++GO:0019227///neuronal action potential propagation+++GO:0021966///corticospinal neuron axon guidance+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0040011///locomotion+++GO:0046684///response to pyrethroid+++GO:0051899///membrane depolarization+++GO:0060048///cardiac muscle contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0061337///cardiac conduction+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086047///membrane depolarization during Purkinje myocyte cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1905150///regulation of voltage-gated sodium channel activity+++GO:2000649///regulation of sodium ion transmembrane transporter activity 20269 20269 'Scn3a' mRNA 0 2 0 0 0.01 0 0.01 0.01 0.01 0.003333333 0.01 1 1 1 0.666666667 1 0.863090843 0.609088544 04742///Taste transduction GO:0001518///voltage-gated sodium channel complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005516///calmodulin binding+++GO:0031402///sodium ion binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0046684///response to pyrethroid+++GO:0055085///transmembrane transport+++GO:0071236///cellular response to antibiotic+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 20271 20271 'Scn5a' mRNA 13 6 4 0.08 0.04 0.03 0.05 0.07 0.05 0.05 0.056666667 9 12 8 7.666666667 9.666666667 0.770731413 0.335984565 04261///Adrenergic signaling in cardiomyocytes GO:0001518///voltage-gated sodium channel complex+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0034706///sodium channel complex+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0017134///fibroblast growth factor binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030506///ankyrin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044325///ion channel binding+++GO:0050998///nitric-oxide synthase binding+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential+++GO:0086060///voltage-gated sodium channel activity involved in AV node cell action potential+++GO:0086061///voltage-gated sodium channel activity involved in bundle of His cell action potential+++GO:0086062///voltage-gated sodium channel activity involved in Purkinje myocyte action potential+++GO:0086063///voltage-gated sodium channel activity involved in SA node cell action potential+++GO:0097110///scaffold protein binding GO:0002027///regulation of heart rate+++GO:0003231///cardiac ventricle development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0010460///positive regulation of heart rate+++GO:0010765///positive regulation of sodium ion transport+++GO:0014070///response to organic cyclic compound+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0045760///positive regulation of action potential+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051899///membrane depolarization+++GO:0055074///calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060048///cardiac muscle contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0071277///cellular response to calcium ion+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086010///membrane depolarization during action potential+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086015///SA node cell action potential+++GO:0086016///AV node cell action potential+++GO:0086043///bundle of His cell action potential+++GO:0086045///membrane depolarization during AV node cell action potential+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0086047///membrane depolarization during Purkinje myocyte cell action potential+++GO:0086048///membrane depolarization during bundle of His cell action potential+++GO:0086065///cell communication involved in cardiac conduction+++GO:0086067///AV node cell to bundle of His cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098655///cation transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:0098912///membrane depolarization during atrial cardiac muscle cell action potential+++GO:1902305///regulation of sodium ion transmembrane transport 20272 20272 'Scn7a' mRNA 287 338 259 2.06 2.39 1.98 3.75 3.39 3.62 2.143333333 3.586666667 601 531 562 294.6666667 564.6666667 5.36E-13 0.929145949 04261///Adrenergic signaling in cardiomyocytes GO:0001518///voltage-gated sodium channel complex+++GO:0005614///interstitial matrix+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031012///extracellular matrix+++GO:0097386///glial cell projection GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0043138///3'-5' DNA helicase activity GO:0003025///regulation of systemic arterial blood pressure by baroreceptor feedback+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006936///muscle contraction+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0007608///sensory perception of smell+++GO:0007626///locomotory behavior+++GO:0009617///response to bacterium+++GO:0019228///neuronal action potential+++GO:0021554///optic nerve development+++GO:0021563///glossopharyngeal nerve development+++GO:0021564///vagus nerve development+++GO:0021695///cerebellar cortex development+++GO:0022008///neurogenesis+++GO:0032508///DNA duplex unwinding+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055078///sodium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0086010///membrane depolarization during action potential 20273 20273 'Scn8a' mRNA 186 213 135 0.86 0.94 0.66 0.27 0.21 0.24 0.82 0.24 68 49 57 178 58 9.39E-11 -1.623598705 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0033268///node of Ranvier+++GO:0034706///sodium channel complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0031402///sodium ion binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007517///muscle organ development+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008344///adult locomotory behavior+++GO:0009636///response to toxic substance+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0050905///neuromuscular process+++GO:0055085///transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 20274 20274 'Scn9a' mRNA 34 36 31 0.18 0.19 0.18 1.25 1.18 1.27 0.183333333 1.233333333 271 250 268 33.66666667 263 1.12E-37 2.955067229 04742///Taste transduction GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0031402///sodium ion binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006954///inflammatory response+++GO:0009636///response to toxic substance+++GO:0009791///post-embryonic development+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0048266///behavioral response to pain+++GO:0055085///transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 20276 20276 'Scnn1a' mRNA 1080 1053 679 17.37 16.44 11.32 12.46 11.32 11.3 15.04333333 11.69333333 911 789 799 937.3333333 833 0.249018016 -0.174078397 04742///Taste transduction+++04960///Aldosterone-regulated sodium reabsorption GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0034706///sodium channel complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0070062///extracellular exosome+++GO:0097228///sperm principal piece+++GO:0098797///plasma membrane protein complex GO:0003779///actin binding+++GO:0005272///sodium channel activity+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0050699///WW domain binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0035725///sodium ion transmembrane transport+++GO:0050878///regulation of body fluid levels+++GO:0050891///multicellular organismal water homeostasis+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0055078///sodium ion homeostasis+++GO:1904045///cellular response to aldosterone 20277 20277 'Scnn1b' mRNA 336 308 357 6.9 6.23 7.78 9.43 10.57 9.17 6.97 9.723333333 528 578 497 333.6666667 534.3333333 1.62E-06 0.6652569 04742///Taste transduction+++04960///Aldosterone-regulated sodium reabsorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034706///sodium channel complex+++GO:0070062///extracellular exosome+++GO:0098797///plasma membrane protein complex GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0050699///WW domain binding "GO:0002028///regulation of sodium ion transport+++GO:0002269///leukocyte activation involved in inflammatory response+++GO:0002283///neutrophil activation involved in immune response+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0009410///response to xenobiotic stimulus+++GO:0010467///gene expression+++GO:0014824///artery smooth muscle contraction+++GO:0032094///response to food+++GO:0032341///aldosterone metabolic process+++GO:0034101///erythrocyte homeostasis+++GO:0035264///multicellular organism growth+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035725///sodium ion transmembrane transport+++GO:0042045///epithelial fluid transport+++GO:0042493///response to drug+++GO:0050891///multicellular organismal water homeostasis+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0055075///potassium ion homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0070254///mucus secretion+++GO:0070944///neutrophil mediated killing of bacterium+++GO:0097274///urea homeostasis+++GO:1904045///cellular response to aldosterone" 20278 20278 'Scnn1g' mRNA 16 15 5 0.29 0.27 0.11 0.51 0.29 0.41 0.223333333 0.403333333 32 18 25 12 25 0.114124177 1.058298332 04742///Taste transduction+++04960///Aldosterone-regulated sodium reabsorption GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0034706///sodium channel complex+++GO:0070062///extracellular exosome+++GO:0098797///plasma membrane protein complex GO:0005216///ion channel activity+++GO:0005272///sodium channel activity+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0050699///WW domain binding "GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035725///sodium ion transmembrane transport+++GO:0050891///multicellular organismal water homeostasis+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0055078///sodium ion homeostasis+++GO:1904045///cellular response to aldosterone" 20280 20280 'Scp2' mRNA 3521 3802 3588 73.25 77.86 79.18 83.72 83.39 84.71 76.76333333 83.94 4629 4503 4535 3637 4555.666667 2.96E-07 0.312909005 00120///Primary bile acid biosynthesis+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031315///extrinsic component of mitochondrial outer membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000062///fatty-acyl-CoA binding+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0015485///cholesterol binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0032934///sterol binding+++GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0050633///acetyl-CoA C-myristoyltransferase activity+++GO:0070538///oleic acid binding+++GO:0120019///intermembrane phosphotidylcholine transfer activity+++GO:0120020///intermembrane cholesterol transfer activity+++GO:1904121///phosphatidylethanolamine transporter activity" GO:0006635///fatty acid beta-oxidation+++GO:0006637///acyl-CoA metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006701///progesterone biosynthetic process+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0007568///aging+++GO:0008206///bile acid metabolic process+++GO:0010893///positive regulation of steroid biosynthetic process+++GO:0015914///phospholipid transport+++GO:0032367///intracellular cholesterol transport+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0043065///positive regulation of apoptotic process+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045940///positive regulation of steroid metabolic process+++GO:0071071///regulation of phospholipid biosynthetic process+++GO:0072659///protein localization to plasma membrane+++GO:1901373///lipid hydroperoxide transport+++GO:1904109///positive regulation of cholesterol import 20284 20284 'Scrg1' mRNA 808 774 819 79.76 75.03 85.35 30.88 32.78 33.42 80.04666667 32.36 354 364 373 800.3333333 363.6666667 2.30E-24 -1.151103766 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0044306///neuron projection terminus GO:0097168///mesenchymal stem cell proliferation 20286 20286 'Zc3h7b' mRNA 1395.57 1258.25 838.01 11.88 10.48 7.13 6.08 4.75 5.53 9.83 5.453333333 863 651 740 1163.943333 751.3333333 7.08E-06 -0.636043396 GO:0005575///cellular_component GO:0035198///miRNA binding+++GO:0046872///metal ion binding GO:0010608///posttranscriptional regulation of gene expression+++GO:0035196///production of miRNAs involved in gene silencing by miRNA 20287 20287 'Sct' mRNA 6 1 6 0.97 0.16 1.03 1.12 0.88 0.14 0.72 0.713333333 8 6 1 4.333333333 5 0.913559456 0.173534485 04080///Neuroactive ligand-receptor interaction+++04972///Pancreatic secretion+++04976///Bile secretion GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0046659///digestive hormone activity+++GO:0047485///protein N-terminus binding GO:0002024///diet induced thermogenesis+++GO:0007165///signal transduction+++GO:0007420///brain development+++GO:0008542///visual learning+++GO:0009992///cellular water homeostasis+++GO:0021542///dentate gyrus development+++GO:0021766///hippocampus development+++GO:0031667///response to nutrient levels+++GO:0032098///regulation of appetite+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0048167///regulation of synaptic plasticity+++GO:0048566///embryonic digestive tract development+++GO:0050996///positive regulation of lipid catabolic process+++GO:0090187///positive regulation of pancreatic juice secretion+++GO:0090274///positive regulation of somatostatin secretion+++GO:0097150///neuronal stem cell population maintenance+++GO:1903640///negative regulation of gastrin-induced gastric acid secretion 20288 20288 'Msr1' mRNA 84 92 87 1.54 1.95 1.99 53.91 52.78 52.71 1.826666667 53.13333333 3064 2788 2851 87.66666667 2901 0 5.036642539 04145///Phagosome GO:0005581///collagen trimer+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034362///low-density lipoprotein particle GO:0001540///amyloid-beta binding+++GO:0005044///scavenger receptor activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0038024///cargo receptor activity "GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0010629///negative regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010886///positive regulation of cholesterol storage+++GO:0030301///cholesterol transport+++GO:0034381///plasma lipoprotein particle clearance+++GO:0042953///lipoprotein transport+++GO:0097242///amyloid-beta clearance" 20289 20289 'Scx' mRNA 60 69 44 3.27 3.71 2.54 2.08 1.06 1.77 3.173333333 1.636666667 44 22 36 57.66666667 34 0.064811193 -0.770840636 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0001707///mesoderm formation+++GO:0001894///tissue homeostasis+++GO:0001958///endochondral ossification+++GO:0002062///chondrocyte differentiation+++GO:0003179///heart valve morphogenesis+++GO:0003188///heart valve formation+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0030509///BMP signaling pathway+++GO:0032502///developmental process+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035914///skeletal muscle cell differentiation+++GO:0035989///tendon development+++GO:0035990///tendon cell differentiation+++GO:0035992///tendon formation+++GO:0035993///deltoid tuberosity development+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048706///embryonic skeletal system development+++GO:0051216///cartilage development+++GO:0060008///Sertoli cell differentiation+++GO:0060325///face morphogenesis+++GO:0061035///regulation of cartilage development+++GO:0061036///positive regulation of cartilage development+++GO:0061056///sclerotome development+++GO:0071260///cellular response to mechanical stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:2000543///positive regulation of gastrulation" 20290 20290 'Ccl1' mRNA 0 1 1 0 0.17 0.18 0.59 0.15 0.3 0.116666667 0.346666667 4 1 2 0.666666667 2.333333333 0.481132622 1.776424459 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0032740///positive regulation of interleukin-17 production+++GO:0043547///positive regulation of GTPase activity+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050729///positive regulation of inflammatory response+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090026///positive regulation of monocyte chemotaxis 20292 20292 'Ccl11' mRNA 37 46 43 2.17 2.66 2.67 6.13 5.56 4.86 2.5 5.516666667 120 106 92 42 106 8.68E-06 1.322074829 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04657///IL-17 signaling pathway+++05310///Asthma GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031728///CCR3 chemokine receptor binding+++GO:0046983///protein dimerization activity+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002544///chronic inflammatory response+++GO:0002548///monocyte chemotaxis+++GO:0002551///mast cell chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007611///learning or memory+++GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031640///killing of cells of other organism+++GO:0035962///response to interleukin-13+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050768///negative regulation of neurogenesis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060763///mammary duct terminal end bud growth+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070670///response to interleukin-4+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090647///modulation of age-related behavioral decline 20293 20293 'Ccl12' mRNA 235 235 222 35.6 35.55 35.71 242.04 275.48 256.68 35.62 258.0666667 1819 2010 1857 230.6666667 1895.333333 6.89E-198 3.028613482 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05135///Yersinia infection+++05142///Chagas disease+++05144///Malaria+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004672///protein kinase activity+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0016004///phospholipase activator activity+++GO:0031727///CCR2 chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0000165///MAPK cascade+++GO:0001525///angiogenesis+++GO:0002548///monocyte chemotaxis+++GO:0002687///positive regulation of leukocyte migration+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006887///exocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0008360///regulation of cell shape+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0043615///astrocyte cell migration+++GO:0044828///negative regulation by host of viral genome replication+++GO:0048245///eosinophil chemotaxis+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070664///negative regulation of leukocyte proliferation+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0090280///positive regulation of calcium ion import+++GO:1905563///negative regulation of vascular endothelial cell proliferation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000502///negative regulation of natural killer cell chemotaxis 20295 20295 'Ccl17' mRNA 12 7 7 1.94 1.13 1.2 7.82 7.92 5.62 1.423333333 7.12 60 54 39 8.666666667 51 7.10E-07 2.546358894 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031729///CCR4 chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0043547///positive regulation of GTPase activity+++GO:0045662///negative regulation of myoblast differentiation+++GO:0048247///lymphocyte chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 20296 20296 'Ccl2' mRNA 32 19 30 2.7 1.59 2.68 215.89 231.3 215.21 2.323333333 220.8 2931 3058 2821 27 2936.666667 0 6.754079215 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05135///Yersinia infection+++05142///Chagas disease+++05144///Malaria+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0030139///endocytic vesicle+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0044299///C-fiber+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0031727///CCR2 chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding "GO:0000165///MAPK cascade+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001912///positive regulation of leukocyte mediated cytotoxicity+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0002548///monocyte chemotaxis+++GO:0002687///positive regulation of leukocyte migration+++GO:0002693///positive regulation of cellular extravasation+++GO:0006874///cellular calcium ion homeostasis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007568///aging+++GO:0008347///glial cell migration+++GO:0008360///regulation of cell shape+++GO:0009408///response to heat+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0009617///response to bacterium+++GO:0010332///response to gamma radiation+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0014823///response to activity+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019233///sensory perception of pain+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030593///neutrophil chemotaxis+++GO:0031100///animal organ regeneration+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032869///cellular response to insulin stimulus+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033552///response to vitamin B3+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0034612///response to tumor necrosis factor+++GO:0035684///helper T cell extravasation+++GO:0035690///cellular response to drug+++GO:0035702///monocyte homeostasis+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0043615///astrocyte cell migration+++GO:0045471///response to ethanol+++GO:0045785///positive regulation of cell adhesion+++GO:0046677///response to antibiotic+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048245///eosinophil chemotaxis+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050806///positive regulation of synaptic transmission+++GO:0050870///positive regulation of T cell activation+++GO:0051384///response to glucocorticoid+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060135///maternal process involved in female pregnancy+++GO:0060137///maternal process involved in parturition+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071300///cellular response to retinoic acid+++GO:0071318///cellular response to ATP+++GO:0071333///cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071392///cellular response to estradiol stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071402///cellular response to lipoprotein particle stimulus+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090265///positive regulation of immune complex clearance by monocytes and macrophages+++GO:0090280///positive regulation of calcium ion import+++GO:0090303///positive regulation of wound healing+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:1905237///response to cyclosporin A+++GO:1905563///negative regulation of vascular endothelial cell proliferation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000427///positive regulation of apoptotic cell clearance+++GO:2000502///negative regulation of natural killer cell chemotaxis" 20299 20299 'Ccl22' mRNA 2 0 1 0.06 0 0.03 2.49 1.87 2.26 0.03 2.206666667 90 66 79 1 78.33333333 1.71E-11 6.27768777 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04625///C-type lectin receptor signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0043547///positive regulation of GTPase activity+++GO:0048247///lymphocyte chemotaxis+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 20300 20300 'Ccl25' mRNA 97 148 111 4.26 5.51 5.01 4.51 4.82 4.48 4.926666667 4.603333333 111 115 111 118.6666667 112.3333333 0.795012257 -0.08788733 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04672///Intestinal immune network for IgA production GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0031735///CCR10 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0043547///positive regulation of GTPase activity+++GO:0048247///lymphocyte chemotaxis+++GO:0050900///leukocyte migration+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:1903237///negative regulation of leukocyte tethering or rolling 20301 20301 'Ccl27a' mRNA 379.8 343.3 310.86 45.94 43.15 42.64 26.73 28.54 26.47 43.91 27.24666667 238.64 235.31 233.27 344.6533333 235.74 2.39E-04 -0.557249917 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0031728///CCR3 chemokine receptor binding GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071677///positive regulation of mononuclear cell migration+++GO:2000251///positive regulation of actin cytoskeleton reorganization 20302 20302 'Ccl3' mRNA 25 32 31 2.16 2.75 2.85 102.97 107 107.29 2.586666667 105.7533333 1361 1377 1369 29.33333333 1369 1.56E-205 5.53358776 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04620///Toll-like receptor signaling pathway+++05142///Chagas disease+++05163///Human cytomegalovirus infection+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004672///protein kinase activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0031726///CCR1 chemokine receptor binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0048020///CCR chemokine receptor binding GO:0000165///MAPK cascade+++GO:0001649///osteoblast differentiation+++GO:0001775///cell activation+++GO:0002548///monocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006887///exocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0008360///regulation of cell shape+++GO:0009636///response to toxic substance+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010818///T cell chemotaxis+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0019722///calcium-mediated signaling+++GO:0023052///signaling+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042493///response to drug+++GO:0043308///eosinophil degranulation+++GO:0043491///protein kinase B signaling+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0043615///astrocyte cell migration+++GO:0043922///negative regulation by host of viral transcription+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048245///eosinophil chemotaxis+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050729///positive regulation of inflammatory response+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050918///positive chemotaxis+++GO:0051928///positive regulation of calcium ion transport+++GO:0051930///regulation of sensory perception of pain+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070723///response to cholesterol+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0071621///granulocyte chemotaxis+++GO:2000503///positive regulation of natural killer cell chemotaxis 20303 20303 'Ccl4' mRNA 62 69 56 6.88 7.61 6.59 89.62 95.34 83.77 7.026666667 89.57666667 923 955 832 62.33333333 903.3333333 5.64E-137 3.847588934 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05163///Human cytomegalovirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0031726///CCR1 chemokine receptor binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0042802///identical protein binding+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009636///response to toxic substance+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035690///cellular response to drug+++GO:0043117///positive regulation of vascular permeability+++GO:0043547///positive regulation of GTPase activity+++GO:0043922///negative regulation by host of viral transcription+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0051928///positive regulation of calcium ion transport+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071466///cellular response to xenobiotic stimulus+++GO:2000503///positive regulation of natural killer cell chemotaxis 20304 20304 'Ccl5' mRNA 27 32 25 4.14 4.9 4.07 27.74 25.66 27.7 4.37 27.03333333 206 185 198 28 196.3333333 6.23E-27 2.799634065 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04668///TNF signaling pathway+++05020///Prion disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05131///Shigellosis+++05142///Chagas disease+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004672///protein kinase activity+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0016004///phospholipase activator activity+++GO:0030298///receptor signaling protein tyrosine kinase activator activity+++GO:0031726///CCR1 chemokine receptor binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0042056///chemoattractant activity+++GO:0042379///chemokine receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0046817///chemokine receptor antagonist activity+++GO:0048020///CCR chemokine receptor binding GO:0000165///MAPK cascade+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002548///monocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006887///exocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0009636///response to toxic substance+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0031269///pseudopodium assembly+++GO:0031328///positive regulation of cellular biosynthetic process+++GO:0031584///activation of phospholipase D activity+++GO:0031622///positive regulation of fever generation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0034097///response to cytokine+++GO:0034112///positive regulation of homotypic cell-cell adhesion+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:0035688///T-helper 1 cell diapedesis+++GO:0042102///positive regulation of T cell proliferation+++GO:0042119///neutrophil activation+++GO:0042327///positive regulation of phosphorylation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043491///protein kinase B signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0043922///negative regulation by host of viral transcription+++GO:0045071///negative regulation of viral genome replication+++GO:0045666///positive regulation of neuron differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045785///positive regulation of cell adhesion+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050796///regulation of insulin secretion+++GO:0050863///regulation of T cell activation+++GO:0050918///positive chemotaxis+++GO:0051928///positive regulation of calcium ion transport+++GO:0060326///cell chemotaxis+++GO:0060548///negative regulation of cell death+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0070234///positive regulation of T cell apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death+++GO:2000110///negative regulation of macrophage apoptotic process+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000406///positive regulation of T cell migration+++GO:2000503///positive regulation of natural killer cell chemotaxis 20305 20305 'Ccl6' mRNA 184 157 231 7.62 6.42 10.15 621.6 629.34 621.37 8.063333333 624.1033333 17232 17022 16663 190.6666667 16972.33333 1.55E-221 6.455844739 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031726///CCR1 chemokine receptor binding+++GO:0042056///chemoattractant activity+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0043547///positive regulation of GTPase activity+++GO:0048247///lymphocyte chemotaxis+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 20306 20306 'Ccl7' mRNA 50 52 57 4.25 4.38 5.14 241.08 255.59 230.32 4.59 242.33 3246 3351 2994 53 3197 0 5.903352273 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0031727///CCR2 chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0010332///response to gamma radiation+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0043547///positive regulation of GTPase activity+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071361///cellular response to ethanol+++GO:2000503///positive regulation of natural killer cell chemotaxis 20307 20307 'Ccl8' mRNA 348 349 343 56.92 57.07 59.57 834.57 969.14 889.5 57.85333333 897.7366667 5804 6540 5952 346.6666667 6098.666667 0 4.126563122 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004672///protein kinase activity+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0016004///phospholipase activator activity+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006468///protein phosphorylation+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006887///exocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0043547///positive regulation of GTPase activity+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901741///positive regulation of myoblast fusion 20308 20308 'Ccl9' mRNA 82.11 79.64 107.6 1.5 1.43 2.08 108.8 102.64 107.95 1.67 106.4633333 6856.58 6317.5 6587.57 89.78333333 6587.216667 0 6.19094414 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031726///CCR1 chemokine receptor binding+++GO:0042056///chemoattractant activity+++GO:0048020///CCR chemokine receptor binding GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0043547///positive regulation of GTPase activity+++GO:0045662///negative regulation of myoblast differentiation+++GO:0048247///lymphocyte chemotaxis+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor 20309 20309 'Cxcl15' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04060///Cytokine-cytokine receptor interaction+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0045236///CXCR chemokine receptor binding GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0030097///hemopoiesis+++GO:0030593///neutrophil chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide 20310 20310 'Cxcl2' mRNA 40 45 52 2.32 2.58 3.2 9.24 9.48 9.56 2.7 9.426666667 183 183 183 45.66666667 183 4.15E-16 1.988016356 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05134///Legionellosis+++05146///Amoebiasis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0045236///CXCR chemokine receptor binding GO:0001975///response to amphetamine+++GO:0002237///response to molecule of bacterial origin+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009408///response to heat+++GO:0010332///response to gamma radiation+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0032355///response to estradiol+++GO:0042060///wound healing+++GO:0051384///response to glucocorticoid+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070997///neuron death+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1 20311 20311 'Cxcl5' mRNA 3 3 1 0.11 0.1 0.04 0.83 0.38 0.32 0.083333333 0.51 27 12 10 2.333333333 16.33333333 0.004698245 2.797044215 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05133///Pertussis+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0042802///identical protein binding+++GO:0045236///CXCR chemokine receptor binding GO:0001776///leukocyte homeostasis+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0010976///positive regulation of neuron projection development+++GO:0030593///neutrophil chemotaxis+++GO:0031100///animal organ regeneration+++GO:0032496///response to lipopolysaccharide+++GO:0032642///regulation of chemokine production+++GO:0042119///neutrophil activation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070951///regulation of neutrophil mediated killing of gram-negative bacterium+++GO:0071222///cellular response to lipopolysaccharide 20312 20312 'Cx3cl1' mRNA 1296 1221 1249 22.57 20.92 23.07 41.95 45.23 39.59 22.18666667 42.25666667 2772 2919 2533 1255.333333 2741.333333 1.98E-43 1.114706415 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04668///TNF signaling pathway+++05163///Human cytomegalovirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0005125///cytokine activity+++GO:0005178///integrin binding+++GO:0008009///chemokine activity+++GO:0031737///CX3C chemokine receptor binding+++GO:0042056///chemoattractant activity+++GO:0045237///CXCR1 chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001774///microglial cell activation+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002548///monocyte chemotaxis+++GO:0002931///response to ischemia+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010976///positive regulation of neuron projection development+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030168///platelet activation+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032690///negative regulation of interleukin-1 alpha production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0033622///integrin activation+++GO:0035425///autocrine signaling+++GO:0042060///wound healing+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0045785///positive regulation of cell adhesion+++GO:0045906///negative regulation of vasoconstriction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048245///eosinophil chemotaxis+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050902///leukocyte adhesive activation+++GO:0050918///positive chemotaxis+++GO:0051041///positive regulation of calcium-independent cell-cell adhesion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060055///angiogenesis involved in wound healing+++GO:0060080///inhibitory postsynaptic potential+++GO:0060326///cell chemotaxis+++GO:0061518///microglial cell proliferation+++GO:0070050///neuron cellular homeostasis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0098609///cell-cell adhesion+++GO:0110091///negative regulation of hippocampal neuron apoptotic process+++GO:1900450///negative regulation of glutamate receptor signaling pathway+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1903979///negative regulation of microglial cell activation+++GO:1904141///positive regulation of microglial cell migration+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 20315 20315 'Cxcl12' mRNA 2074 2246 2127 55.61 59.68 61.9 133.38 131.5 134.07 59.06333333 132.9833333 5410 5184 5267 2149 5287 6.90E-100 1.286631116 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04360///Axon guidance+++04670///Leukocyte transendothelial migration+++04672///Intestinal immune network for IgA production+++04810///Regulation of actin cytoskeleton+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0005178///integrin binding+++GO:0008009///chemokine activity+++GO:0008083///growth factor activity+++GO:0042379///chemokine receptor binding+++GO:0045236///CXCR chemokine receptor binding GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001667///ameboidal-type cell migration+++GO:0001764///neuron migration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006955///immune response+++GO:0007281///germ cell development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0008045///motor neuron axon guidance+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0008354///germ cell migration+++GO:0009314///response to radiation+++GO:0009408///response to heat+++GO:0009612///response to mechanical stimulus+++GO:0010818///T cell chemotaxis+++GO:0022029///telencephalon cell migration+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0031100///animal organ regeneration+++GO:0031640///killing of cells of other organism+++GO:0033603///positive regulation of dopamine secretion+++GO:0033622///integrin activation+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0042098///T cell proliferation+++GO:0043434///response to peptide hormone+++GO:0045666///positive regulation of neuron differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0050921///positive regulation of chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051924///regulation of calcium ion transport+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071542///dopaminergic neuron differentiation+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090280///positive regulation of calcium ion import+++GO:0098609///cell-cell adhesion+++GO:1901741///positive regulation of myoblast fusion+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1903237///negative regulation of leukocyte tethering or rolling+++GO:1990478///response to ultrasound+++GO:1990869///cellular response to chemokine+++GO:2000406///positive regulation of T cell migration+++GO:2000669///negative regulation of dendritic cell apoptotic process 20316 20316 'Sdf2' mRNA 2124 2122 2112 101.86 100.61 107.67 111.14 110.4 107.87 103.38 109.8033333 2656 2572 2494 2119.333333 2574 1.39E-04 0.267728129 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0101031///chaperone complex GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0051787///misfolded protein binding GO:0035269///protein O-linked mannosylation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071712///ER-associated misfolded protein catabolic process 20317 20317 'Serpinf1' mRNA 908 889 808 35.94 34.7 33.93 88.24 93.57 88.89 34.85666667 90.23333333 2561 2650 2496 868.3333333 2569 2.35E-97 1.555016134 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0043203///axon hillock+++GO:0048471///perinuclear region of cytoplasm GO:0004867///serine-type endopeptidase inhibitor activity GO:0001822///kidney development+++GO:0007568///aging+++GO:0007614///short-term memory+++GO:0010447///response to acidic pH+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0014070///response to organic cyclic compound+++GO:0016525///negative regulation of angiogenesis+++GO:0042698///ovulation cycle+++GO:0046685///response to arsenic-containing substance+++GO:0050728///negative regulation of inflammatory response+++GO:0050769///positive regulation of neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0071279///cellular response to cobalt ion+++GO:0071300///cellular response to retinoic acid+++GO:0071333///cellular response to glucose stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1901215///negative regulation of neuron death+++GO:1901652///response to peptide 20318 20318 'Sdf4' mRNA 7129 7141 7036 118.22 120.66 126.51 124.4 137.44 136.67 121.7966667 132.8366667 7881 7744 7954 7102 7859.666667 0.022510357 0.13392348 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0009650///UV protection+++GO:0017156///calcium ion regulated exocytosis+++GO:0021549///cerebellum development+++GO:0045444///fat cell differentiation+++GO:0045471///response to ethanol+++GO:0070625///zymogen granule exocytosis+++GO:0099558///maintenance of synapse structure 20319 20319 'Sfrp2' mRNA 538 505 467 15.31 14.15 14.1 6.81 6.95 5.93 14.52 6.563333333 275 274 232 503.3333333 260.3333333 9.00E-13 -0.961643839 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0017147///Wnt-protein binding+++GO:0048018///receptor ligand activity+++GO:0061133///endopeptidase activator activity "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0002063///chondrocyte development+++GO:0003151///outflow tract morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007584///response to nutrient+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0010629///negative regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010950///positive regulation of endopeptidase activity+++GO:0010975///regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0021915///neural tube development+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030199///collagen fibril organization+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031668///cellular response to extracellular stimulus+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0042733///embryonic digit morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046546///development of primary male sexual characteristics+++GO:0048546///digestive tract morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0051216///cartilage development+++GO:0060028///convergent extension involved in axis elongation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060349///bone morphogenesis+++GO:0061056///sclerotome development+++GO:0061185///negative regulation of dermatome development+++GO:0071425///hematopoietic stem cell proliferation+++GO:0071481///cellular response to X-ray+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090175///regulation of establishment of planar polarity+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904956///regulation of midbrain dopaminergic neuron differentiation+++GO:2000035///regulation of stem cell division+++GO:2000041///negative regulation of planar cell polarity pathway involved in axis elongation" 20320 20320 'Nptn' mRNA 4234 4117 3914 116.23 110.03 112.85 102.45 89.32 100.67 113.0366667 97.48 4311 3672 4079 4088.333333 4020.666667 0.67373063 -0.036532806 GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0060077///inhibitory synapse+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0050839///cell adhesion molecule binding+++GO:0098632///cell-cell adhesion mediator activity "GO:0001818///negative regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008542///visual learning+++GO:0010976///positive regulation of neuron projection development+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0060291///long-term synaptic potentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070593///dendrite self-avoidance+++GO:0099557///trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1902683///regulation of receptor localization to synapse+++GO:1903829///positive regulation of cellular protein localization+++GO:1904861///excitatory synapse assembly" 20321 20321 'Frrs1' mRNA 233 270 256 5.2 5.92 6.06 16.54 17.33 15.92 5.726666667 16.59666667 858 880 799 253 845.6666667 5.42E-48 1.729107488 GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0046872///metal ion binding" GO:0006879///cellular iron ion homeostasis 20322 20322 'Sord' mRNA 950 988 912 23.65 24.22 24.08 29.89 31.37 30.41 23.98333333 30.55666667 1381 1415 1360 950 1385.333333 8.94E-11 0.533530577 00040///Pentose and glucuronate interconversions+++00051///Fructose and mannose metabolism GO:0005739///mitochondrion+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0031966///mitochondrial membrane+++GO:0042995///cell projection+++GO:0070062///extracellular exosome GO:0003939///L-iditol 2-dehydrogenase activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046526///D-xylulose reductase activity+++GO:0046872///metal ion binding+++GO:0051287///NAD binding GO:0006060///sorbitol metabolic process+++GO:0006062///sorbitol catabolic process+++GO:0006970///response to osmotic stress+++GO:0009725///response to hormone+++GO:0030317///flagellated sperm motility+++GO:0031667///response to nutrient levels+++GO:0042493///response to drug+++GO:0046370///fructose biosynthetic process+++GO:0046686///response to cadmium ion+++GO:0046688///response to copper ion+++GO:0051160///L-xylitol catabolic process+++GO:0051164///L-xylitol metabolic process 20324 20324 'Cavin2' mRNA 1344 1391 1263 24.13 24.58 24.06 17.23 18.33 17.02 24.25666667 17.52666667 1104 1147 1056 1332.666667 1102.333333 8.79E-04 -0.284058707 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0045121///membrane raft GO:0001786///phosphatidylserine binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008289///lipid binding GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097320///plasma membrane tubulation 20333 20333 'Sec22b' mRNA 1758 1911 1725 55.77 59.74 58.05 68.2 66.73 68.45 57.85333333 67.79333333 2471 2360 2400 1798 2410.333333 1.49E-09 0.411704226 04130///SNARE interactions in vesicular transport+++04145///Phagosome+++05134///Legionellosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030137///COPI-coated vesicle+++GO:0031201///SNARE complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042470///melanosome GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0061025///membrane fusion+++GO:1902902///negative regulation of autophagosome assembly" 20334 20334 'Sec23a' mRNA 1203 1312 1266 15.79 16.93 17.62 17.41 15.42 16.97 16.78 16.6 1527 1321 1442 1260.333333 1430 0.071014306 0.168706411 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030127///COPII vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0072659///protein localization to plasma membrane+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding 20335 20335 'Sec61g' mRNA 1253 1328 1628 115.37 121.3 159.11 154.88 178.94 182.29 131.9266667 172.0366667 1927 2165 2187 1403 2093 1.38E-06 0.559930606 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05110///Vibrio cholerae infection GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071261///Ssh1 translocon complex GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity "GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0031204///posttranslational protein targeting to membrane, translocation" 20336 20336 'Exoc4' mRNA 1312 1323 1127 15.7 15.88 14.21 11.45 11.34 11.2 15.26333333 11.33 1084 1051 1047 1254 1060.666667 0.00372925 -0.250785802 05132///Salmonella infection GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0032584///growth cone membrane+++GO:0032991///protein-containing complex+++GO:0035748///myelin sheath abaxonal region+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043209///myelin sheath+++GO:0045202///synapse+++GO:0090543///Flemming body GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0006612///protein targeting to membrane+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0015031///protein transport+++GO:0030010///establishment of cell polarity+++GO:0044091///membrane biogenesis+++GO:0048341///paraxial mesoderm formation+++GO:0048709///oligodendrocyte differentiation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0051223///regulation of protein transport+++GO:0055108///Golgi to transport vesicle transport+++GO:0060271///cilium assembly+++GO:0090522///vesicle tethering involved in exocytosis+++GO:1903441///protein localization to ciliary membrane 20338 20338 'Sel1l' mRNA 3428 3578 3570 28.86 29.62 31.89 27.09 26.66 26.91 30.12333333 26.88666667 3702 3558 3561 3525.333333 3607 0.836368634 0.019801503 04141///Protein processing in endoplasmic reticulum GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036513///Derlin-1 retrotranslocation complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding "GO:0006641///triglyceride metabolic process+++GO:0007219///Notch signaling pathway+++GO:0009306///protein secretion+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036503///ERAD pathway" 20339 20339 'Sele' mRNA 21 17 10 0.28 0.26 0.14 0.35 0.21 0.44 0.226666667 0.333333333 30 18 37 16 28.33333333 0.182526531 0.819917527 04514///Cell adhesion molecules+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05143///African trypanosomiasis+++05144///Malaria+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030863///cortical cytoskeleton+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0043274///phospholipase binding+++GO:0046872///metal ion binding+++GO:0070492///oligosaccharide binding GO:0002092///positive regulation of receptor internalization+++GO:0002687///positive regulation of leukocyte migration+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007202///activation of phospholipase C activity+++GO:0030029///actin filament-based process+++GO:0034097///response to cytokine+++GO:0050901///leukocyte tethering or rolling+++GO:0070555///response to interleukin-1+++GO:1903238///positive regulation of leukocyte tethering or rolling 20340 20340 'Glg1' mRNA 4005 3695.98 3065 25.88 23.48 21.02 20.45 19.73 20.8 23.46 20.32666667 3644 3435 3590 3588.66 3556.333333 0.854104166 -0.020747315 04514///Cell adhesion molecules GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0017134///fibroblast growth factor binding+++GO:0030246///carbohydrate binding GO:0010955///negative regulation of protein processing+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032330///regulation of chondrocyte differentiation+++GO:0060349///bone morphogenesis 20341 20341 'Selenbp1' mRNA 637.86 703.74 701.85 22 23.93 25.68 29.17 27.99 28.17 23.87 28.44333333 971.74 909.96 908.18 681.15 929.96 2.04E-05 0.43634284 00920///Sulfur metabolism GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity+++GO:0018549///methanethiol oxidase activity GO:0015031///protein transport+++GO:0050873///brown fat cell differentiation 20342 20342 'Selenbp2' mRNA 48.14 73.26 50.15 1.65 2.47 1.82 2.3 2.54 2.12 1.98 2.32 77.26 83.04 68.82 57.18333333 76.37333333 0.249764048 0.408035216 00920///Sulfur metabolism GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008430///selenium binding GO:0015031///protein transport 20343 20343 'Sell' mRNA 18 15 19 0.43 0.36 0.49 3.27 3.72 3.24 0.426666667 3.41 148 173 149 17.33333333 156.6666667 8.27E-24 3.164234492 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002020///protease binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0051861///glycolipid binding+++GO:0070492///oligosaccharide binding GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0033198///response to ATP+++GO:0042981///regulation of apoptotic process+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0090023///positive regulation of neutrophil chemotaxis 20344 20344 'Selp' mRNA 24 50 44 0.38 0.78 0.74 0.83 0.76 0.6 0.633333333 0.73 60 54 42 39.33333333 52 0.412622832 0.387157801 04514///Cell adhesion molecules+++04613///Neutrophil extracellular trap formation+++05144///Malaria+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031092///platelet alpha granule membrane GO:0001530///lipopolysaccharide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0042806///fucose binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0070492///oligosaccharide binding GO:0002687///positive regulation of leukocyte migration+++GO:0002691///regulation of cellular extravasation+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0010572///positive regulation of platelet activation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0033623///regulation of integrin activation+++GO:0034097///response to cytokine+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0045785///positive regulation of cell adhesion+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0071354///cellular response to interleukin-6+++GO:0098609///cell-cell adhesion+++GO:1903238///positive regulation of leukocyte tethering or rolling 20345 20345 'Selplg' mRNA 93 91 85 2.78 2.8 2.71 31.8 32 30.83 2.763333333 31.54333333 1225 1188 1149 89.66666667 1187.333333 8.16E-182 3.716110407 04514///Cell adhesion molecules+++04613///Neutrophil extracellular trap formation+++05150///Staphylococcus aureus infection GO:0001931///uropod+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0007155///cell adhesion+++GO:0030097///hemopoiesis+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0050902///leukocyte adhesive activation 20346 20346 'Sema3a' mRNA 375 385 328 3.3 3.43 2.94 0.78 0.66 0.63 3.223333333 0.69 97 80 77 362.6666667 84.66666667 5.64E-33 -2.109248973 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0001764///neuron migration+++GO:0002027///regulation of heart rate+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0008045///motor neuron axon guidance+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010977///negative regulation of neuron projection development+++GO:0021612///facial nerve structural organization+++GO:0021637///trigeminal nerve structural organization+++GO:0021675///nerve development+++GO:0021772///olfactory bulb development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0036486///ventral trunk neural crest cell migration+++GO:0048813///dendrite morphogenesis+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0060385///axonogenesis involved in innervation+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0061549///sympathetic ganglion development+++GO:0061551///trigeminal ganglion development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097490///sympathetic neuron projection extension+++GO:0097491///sympathetic neuron projection guidance+++GO:0150020///basal dendrite arborization+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1903045///neural crest cell migration involved in sympathetic nervous system development+++GO:1903375///facioacoustic ganglion development+++GO:2000020///positive regulation of male gonad development+++GO:2001224///positive regulation of neuron migration 20347 20347 'Sema3b' mRNA 3862.92 4038.92 3933.96 69.73 70.71 74.54 43.69 44.78 40.18 71.66 42.88333333 2821 2764.96 2497.98 3945.266667 2694.646667 3.37E-16 -0.562766351 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20348 20348 'Sema3c' mRNA 819 806 798 8.83 8.55 9.13 4.84 4.52 5.06 8.836666667 4.806666667 517 471 523 807.6666667 503.6666667 2.79E-11 -0.693907923 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0001756///somitogenesis+++GO:0001974///blood vessel remodeling+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003350///pulmonary myocardium development+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007507///heart development+++GO:0009791///post-embryonic development+++GO:0021915///neural tube development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0060174///limb bud formation+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0140074///cardiac endothelial to mesenchymal transition+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis 20349 20349 'Sema3e' mRNA 1196.99 1210 1072 9.22 9.16 8.76 6.84 5.61 5.79 9.046666667 6.08 1023 819.04 839 1159.663333 893.68 8.84E-05 -0.387354394 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001755///neural crest cell migration+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002040///sprouting angiogenesis+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050808///synapse organization+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:2000249///regulation of actin cytoskeleton reorganization 20350 20350 'Sema3f' mRNA 203 197 203 3.35 3.13 3.53 4.37 3.79 4.07 3.336666667 4.076666667 308 256 283 201 282.3333333 0.004971881 0.476206862 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0021612///facial nerve structural organization+++GO:0021637///trigeminal nerve structural organization+++GO:0021675///nerve development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0030335///positive regulation of cell migration+++GO:0036486///ventral trunk neural crest cell migration+++GO:0040011///locomotion+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0061549///sympathetic ganglion development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097490///sympathetic neuron projection extension+++GO:0097491///sympathetic neuron projection guidance+++GO:0099175///regulation of postsynapse organization+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 20351 20351 'Sema4a' mRNA 206 202 179 3.63 3.52 3.38 10.96 11.98 10.53 3.51 11.15666667 708 761 668 195.6666667 712.3333333 1.07E-47 1.854842414 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001525///angiogenesis+++GO:0001755///neural crest cell migration+++GO:0002250///adaptive immune response+++GO:0002292///T cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0010594///regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0045063///T-helper 1 cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1904891///positive regulation of excitatory synapse assembly+++GO:1905704///positive regulation of inhibitory synapse assembly 20352 20352 'Sema4b' mRNA 780 682 697 10.66 9.24 10.1 6.6 6.25 7.28 10 6.71 554 514 591 719.6666667 553 6.93E-04 -0.392149828 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20353 20353 'Sema4c' mRNA 929 921.71 397.6 11.69 11.1 5.24 3.52 3.8 3.93 9.343333333 3.75 306.11 342.25 346.94 749.4366667 331.7666667 0.002196871 -1.169043435 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0001843///neural tube closure+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0021535///cell migration in hindbrain+++GO:0021549///cerebellum development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0042692///muscle cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20354 20354 'Sema4d' mRNA 984.53 1110.47 1021.86 12.71 14.29 14.12 15.82 14.77 16.36 13.70666667 15.65 1423.06 1286.09 1416.33 1038.953333 1375.16 8.27E-06 0.392984888 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0045499///chemorepellent activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031344///regulation of cell projection organization+++GO:0043547///positive regulation of GTPase activity+++GO:0043931///ossification involved in bone maturation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0048672///positive regulation of collateral sprouting+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0050919///negative chemotaxis+++GO:0070486///leukocyte aggregation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:1905704///positive regulation of inhibitory synapse assembly 20355 20355 'Sema4f' mRNA 1389 1425 922 18.34 18.56 13.09 2.89 4.07 3.74 16.66333333 3.566666667 248 343 313 1245.333333 301.3333333 3.96E-44 -2.046902057 04360///Axon guidance GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0031290///retinal ganglion cell axon guidance+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20356 20356 'Sema5a' mRNA 1474 1541 1363 7.15 7.35 7.02 5.94 5.21 5.38 7.173333333 5.51 1414 1211 1240 1459.333333 1288.333333 0.028555711 -0.191235197 04360///Axon guidance GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008046///axon guidance receptor activity+++GO:0030215///semaphorin receptor binding+++GO:0035373///chondroitin sulfate proteoglycan binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0045499///chemorepellent activity+++GO:0045545///syndecan binding GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001755///neural crest cell migration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0021536///diencephalon development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0045766///positive regulation of angiogenesis+++GO:0048675///axon extension+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0050918///positive chemotaxis+++GO:0050919///negative chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097485///neuron projection guidance+++GO:1990138///neuron projection extension+++GO:1990256///signal clustering+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2001028///positive regulation of endothelial cell chemotaxis 20357 20357 'Sema5b' mRNA 24 16 19 0.27 0.19 0.24 0.13 0.06 0.1 0.233333333 0.096666667 13 6 9 19.66666667 9.333333333 0.129049127 -1.092826996 04360///Axon guidance GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048675///axon extension+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097485///neuron projection guidance+++GO:1990138///neuron projection extension 20358 20358 'Sema6a' mRNA 1362 1354 1287 6.72 6.71 6.84 4.82 4.39 4.55 6.756666667 4.586666667 1090 950 997 1334.333333 1012.333333 1.15E-06 -0.410804689 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0042802///identical protein binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0001764///neuron migration+++GO:0006915///apoptotic process+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0051642///centrosome localization+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0106089///negative regulation of cell adhesion involved in sprouting angiogenesis+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:2001224///positive regulation of neuron migration 20359 20359 'Sema6b' mRNA 138 134 61 1.91 1.87 0.92 0.62 0.55 0.77 1.566666667 0.646666667 51 44 61 111 52 0.001315224 -1.091108261 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0021766///hippocampus development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20360 20360 'Sema6c' mRNA 293 298 83 4.01 4.2 1.25 0.75 1.11 1.52 3.153333333 1.126666667 61 88 118 224.6666667 89 0.042643875 -1.318768166 04360///Axon guidance GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 20361 20361 'Sema7a' mRNA 51 51 44 1.08 1.07 0.88 2.01 2.04 1.75 1.01 1.933333333 114 114 98 48.66666667 108.6666667 4.57E-05 1.14916945 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0005178///integrin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0021988///olfactory lobe development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031175///neuron projection development+++GO:0045773///positive regulation of axon extension+++GO:0048675///axon extension+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050727///regulation of inflammatory response+++GO:0050919///negative chemotaxis+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071526///semaphorin-plexin signaling pathway 20362 20362 'Septin8' mRNA 1305 1411 1321 17.12 18.53 18.51 20.2 19.5 20.34 18.05333333 20.01333333 1840 1704 1771 1345.666667 1771.666667 5.23E-07 0.384643192 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031105///septin complex+++GO:0031410///cytoplasmic vesicle+++GO:0032153///cell division site+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045202///synapse+++GO:0098793///presynapse GO:0000149///SNARE binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0060090///molecular adaptor activity GO:0031647///regulation of protein stability+++GO:0033157///regulation of intracellular protein transport+++GO:0034613///cellular protein localization+++GO:0035542///regulation of SNARE complex assembly+++GO:0061640///cytoskeleton-dependent cytokinesis 20363 20363 'Selenop' mRNA 9097.25 9544.22 9316.32 254.44 262.99 276.45 776.72 755.47 765.05 264.6266667 765.7466667 31930.1 30321.66 30446.04 9319.263333 30899.26667 2.15E-247 1.716346178 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0008430///selenium binding GO:0001887///selenium compound metabolic process+++GO:0007420///brain development+++GO:0007626///locomotory behavior+++GO:0009791///post-embryonic development+++GO:0019953///sexual reproduction+++GO:0040008///regulation of growth 20364 20364 'Selenow' mRNA 10784 10550 10397 1090.08 1058.89 1115.41 850.65 955.44 886.82 1088.126667 897.6366667 9620 10514 9676 10577 9936.666667 0.146062781 -0.101332922 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity GO:0010269///response to selenium ion+++GO:0098869///cellular oxidant detoxification 20365 20365 'Serf1' mRNA 442 392 422 57.91 51.16 58.69 24.47 25.06 25.87 55.92 25.13333333 213 212 217 418.6666667 214 1.56E-11 -0.98120414 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0031648///protein destabilization+++GO:1990000///amyloid fibril formation 20370 20370 'Sez6' mRNA 19 13 14 0.3 0.18 0.25 0.53 0.23 0.36 0.243333333 0.373333333 42 20 28 15.33333333 30 0.104747244 0.951440932 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite GO:0003674///molecular_function GO:0008344///adult locomotory behavior+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0050773///regulation of dendrite development+++GO:0060074///synapse maturation+++GO:0060079///excitatory postsynaptic potential+++GO:0090036///regulation of protein kinase C signaling+++GO:1900006///positive regulation of dendrite development+++GO:2000171///negative regulation of dendrite development 20371 20371 'Foxp3' mRNA 0 2.15 3.22 0 0.03 0.05 0.04 0.03 0.04 0.026666667 0.036666667 3.14 2.13 3.18 1.79 2.816666667 0.778026136 0.644077319 04659///Th17 cell differentiation+++05321///Inflammatory bowel disease GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0035035///histone acetyltransferase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051525///NFAT protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001782///B cell homeostasis+++GO:0001816///cytokine production+++GO:0001818///negative regulation of cytokine production+++GO:0002262///myeloid cell homeostasis+++GO:0002362///CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment+++GO:0002456///T cell mediated immunity+++GO:0002507///tolerance induction+++GO:0002513///tolerance induction to self antigen+++GO:0002637///regulation of immunoglobulin production+++GO:0002666///positive regulation of T cell tolerance induction+++GO:0002667///regulation of T cell anergy+++GO:0002669///positive regulation of T cell anergy+++GO:0002677///negative regulation of chronic inflammatory response+++GO:0002725///negative regulation of T cell cytokine production+++GO:0002851///positive regulation of peripheral T cell tolerance induction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0009314///response to radiation+++GO:0009615///response to virus+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014045///establishment of endothelial blood-brain barrier+++GO:0031064///negative regulation of histone deacetylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032496///response to lipopolysaccharide+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032713///negative regulation of interleukin-4 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0032831///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0033092///positive regulation of immature T cell proliferation in thymus+++GO:0035066///positive regulation of histone acetylation+++GO:0035067///negative regulation of histone acetylation+++GO:0042110///T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048294///negative regulation of isotype switching to IgE isotypes+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:0050687///negative regulation of defense response to virus+++GO:0050728///negative regulation of inflammatory response+++GO:0050777///negative regulation of immune response+++GO:0050852///T cell receptor signaling pathway+++GO:1901355///response to rapamycin+++GO:2000320///negative regulation of T-helper 17 cell differentiation" 20375 20375 'Spi1' mRNA 139 170 139 5.67 6.99 6.02 56.77 92.15 91.73 6.226666667 80.21666667 1588 2512 2488 149.3333333 2196 1.98E-51 3.873732529 04380///Osteoclast differentiation+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0051525///NFAT protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0097677///STAT family protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001944///vasculature development+++GO:0002314///germinal center B cell differentiation+++GO:0002316///follicular B cell differentiation+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0002327///immature B cell differentiation+++GO:0002357///defense response to tumor cell+++GO:0002572///pro-T cell differentiation+++GO:0002573///myeloid leukocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030098///lymphocyte differentiation+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030225///macrophage differentiation+++GO:0030851///granulocyte differentiation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034401///chromatin organization involved in regulation of transcription+++GO:0035019///somatic stem cell population maintenance+++GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0043966///histone H3 acetylation+++GO:0044027///hypermethylation of CpG island+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0045646///regulation of erythrocyte differentiation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0060033///anatomical structure regression+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071361///cellular response to ethanol+++GO:0090241///negative regulation of histone H4 acetylation+++GO:0090402///oncogene-induced cell senescence+++GO:0098508///endothelial to hematopoietic transition+++GO:0120186///negative regulation of protein localization to chromatin+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901674///regulation of histone H3-K27 acetylation+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904151///positive regulation of microglial cell mediated cytotoxicity+++GO:1904178///negative regulation of adipose tissue development+++GO:1904238///pericyte cell differentiation+++GO:1905036///positive regulation of antifungal innate immune response+++GO:1905453///regulation of myeloid progenitor cell differentiation+++GO:2000529///positive regulation of myeloid dendritic cell chemotaxis" 20377 20377 'Sfrp1' mRNA 7003 7168 4208 86.06 86.62 54.85 22.3 19.33 24.2 75.84333333 21.94333333 2091 1772 2196 6126.333333 2019.666667 1.09E-13 -1.601924863 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0062023///collagen-containing extracellular matrix GO:0004197///cysteine-type endopeptidase activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0017147///Wnt-protein binding+++GO:0042802///identical protein binding "GO:0001649///osteoblast differentiation+++GO:0001657///ureteric bud development+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006508///proteolysis+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009267///cellular response to starvation+++GO:0009410///response to xenobiotic stimulus+++GO:0009950///dorsal/ventral axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010564///regulation of cell cycle process+++GO:0010629///negative regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010975///regulation of neuron projection development+++GO:0014034///neural crest cell fate commitment+++GO:0014070///response to organic cyclic compound+++GO:0016055///Wnt signaling pathway+++GO:0021915///neural tube development+++GO:0030036///actin cytoskeleton organization+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030278///regulation of ossification+++GO:0030279///negative regulation of ossification+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035019///somatic stem cell population maintenance+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0044345///stromal-epithelial cell signaling involved in prostate gland development+++GO:0045578///negative regulation of B cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046546///development of primary male sexual characteristics+++GO:0046676///negative regulation of insulin secretion+++GO:0046851///negative regulation of bone remodeling+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048546///digestive tract morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060346///bone trabecula formation+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0060687///regulation of branching involved in prostate gland morphogenesis+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0071305///cellular response to vitamin D+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071481///cellular response to X-ray+++GO:0071504///cellular response to heparin+++GO:0071542///dopaminergic neuron differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071773///cellular response to BMP stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090175///regulation of establishment of planar polarity+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0090246///convergent extension involved in somitogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904956///regulation of midbrain dopaminergic neuron differentiation+++GO:2000041///negative regulation of planar cell polarity pathway involved in axis elongation+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:2000054///negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification+++GO:2000080///negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 20378 20378 'Frzb' mRNA 1918 2038 1913 36.15 37.8 38.25 27.77 26.94 26.73 37.4 27.14666667 1695 1606 1580 1956.333333 1627 1.73E-04 -0.277948074 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0017147///Wnt-protein binding GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0010721///negative regulation of cell development+++GO:0014033///neural crest cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0042472///inner ear morphogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0060029///convergent extension involved in organogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0061037///negative regulation of cartilage development+++GO:0061053///somite development+++GO:0070367///negative regulation of hepatocyte differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090103///cochlea morphogenesis 20379 20379 'Sfrp4' mRNA 4185 4241 4347 137.43 137.27 151.44 782.76 815.44 784.58 142.0466667 794.26 27394 27854 26571 4257.666667 27273 0 2.666200968 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0009986///cell surface GO:0017147///Wnt-protein binding GO:0002092///positive regulation of receptor internalization+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030510///regulation of BMP signaling pathway+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0046329///negative regulation of JNK cascade+++GO:0055062///phosphate ion homeostasis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060349///bone morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902174///positive regulation of keratinocyte apoptotic process+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway+++GO:2000119///negative regulation of sodium-dependent phosphate transport 20382 20382 'Srsf2' mRNA 3154.91 3036.98 1608.72 68.81 67.79 38.92 32.76 34.2 42.1 58.50666667 36.35333333 1559.87 1588.86 1992.93 2600.203333 1713.886667 0.052433422 -0.598062348 03040///Spliceosome+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0035061///interchromatin granule GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding "GO:0000278///mitotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0033197///response to vitamin E" 20383 20383 'Srsf3' mRNA 3970 3938 3964 85.32 83.32 90.38 89.65 81.95 87.6 86.34 86.4 4798 4283 4539 3957.333333 4540 0.005547032 0.184502531 03040///Spliceosome+++05014///Amyotrophic lateral sclerosis+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043274///phospholipase binding+++GO:1990825///sequence-specific mRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008286///insulin receptor signaling pathway+++GO:0008380///RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0051028///mRNA transport+++GO:1990830///cellular response to leukemia inhibitory factor" 20384 20384 'Srsf5' mRNA 9818 9632 9453 366.89 355.55 375.45 238.94 233.93 236.69 365.9633333 236.52 7279 6945 6975 9634.333333 7066.333333 9.20E-19 -0.459642898 03040///Spliceosome+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0043422///protein kinase B binding+++GO:0050733///RS domain binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0001889///liver development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0009611///response to wounding+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0033120///positive regulation of RNA splicing+++GO:0051726///regulation of cell cycle+++GO:0097421///liver regeneration" 20387 20387 'Sftpa1' mRNA 29 38 35 0.58 0.74 0.74 0.47 0.74 0.63 0.686666667 0.613333333 27 42 35 34 34.66666667 0.978447072 0.018984289 04145///Phagosome+++05133///Pertussis GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005771///multivesicular body+++GO:0005791///rough endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0007585///respiratory gaseous exchange+++GO:0007623///circadian rhythm+++GO:0008228///opsonization+++GO:0009725///response to hormone+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0033189///response to vitamin A+++GO:0050766///positive regulation of phagocytosis+++GO:0051384///response to glucocorticoid+++GO:0055093///response to hyperoxia+++GO:0070741///response to interleukin-6+++GO:0070849///response to epidermal growth factor+++GO:0071260///cellular response to mechanical stimulus+++GO:0071732///cellular response to nitric oxide 20388 20388 'Sftpb' mRNA 37 44 34 1.39 1.66 1.37 1.03 1.65 1.03 1.473333333 1.236666667 31 49 30 38.33333333 36.66666667 0.897257951 -0.069080604 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005771///multivesicular body+++GO:0062023///collagen-containing extracellular matrix+++GO:0097208///alveolar lamellar body GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0007585///respiratory gaseous exchange 20389 20389 'Sftpc' mRNA 0 1 0 0 0.08 0 0 0 0.08 0.026666667 0.026666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097208///alveolar lamellar body GO:0042802///identical protein binding GO:0007585///respiratory gaseous exchange 20390 20390 'Sftpd' mRNA 25 12 28 1.14 0.54 1.35 7.09 7.1 6.8 1.01 6.996666667 179 175 166 21.66666667 173.3333333 2.52E-22 2.981722713 04145///Phagosome GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005791///rough endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0062023///collagen-containing extracellular matrix GO:0001530///lipopolysaccharide binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0048029///monosaccharide binding GO:0002376///immune system process+++GO:0007585///respiratory gaseous exchange+++GO:0008228///opsonization+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0043129///surfactant homeostasis+++GO:0043152///induction of bacterial agglutination+++GO:0045087///innate immune response+++GO:0048286///lung alveolus development+++GO:0050765///negative regulation of phagocytosis+++GO:0050766///positive regulation of phagocytosis+++GO:0050828///regulation of liquid surface tension+++GO:0052403///negative regulation by host of symbiont catalytic activity+++GO:0052405///negative regulation by host of symbiont molecular function+++GO:1905226///regulation of adhesion of symbiont to host epithelial cell 20391 20391 'Sgca' mRNA 1 0 2 0.04 0 0.09 0.04 0 0.04 0.043333333 0.026666667 1 0 1 1 0.666666667 0.863090843 -0.640706422 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016011///dystroglycan complex+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma+++GO:0045121///membrane raft GO:0005509///calcium ion binding GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0043403///skeletal muscle tissue regeneration+++GO:0061024///membrane organization 20392 20392 'Sgce' mRNA 1049 1018 942 35.69 34.19 33.95 24.38 23.08 21.82 34.61 23.09333333 817 758 706 1003 760.3333333 1.68E-05 -0.410866486 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection GO:0005515///protein binding 20393 20393 'Sgk1' mRNA 4713 5040 4977 106.29 111.95 119.09 165.05 162.63 164.22 112.4433333 163.9666667 8404 8083 8088 4910 8191.666667 5.16E-34 0.725192361 04068///FoxO signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04960///Aldosterone-regulated sodium reabsorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015459///potassium channel regulator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043423///3-phosphoinositide-dependent protein kinase binding+++GO:0048156///tau protein binding GO:0006468///protein phosphorylation+++GO:0006883///cellular sodium ion homeostasis+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007019///microtubule depolymerization+++GO:0007616///long-term memory+++GO:0008542///visual learning+++GO:0010765///positive regulation of sodium ion transport+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0031115///negative regulation of microtubule polymerization+++GO:0032869///cellular response to insulin stimulus+++GO:0032880///regulation of protein localization+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0043402///glucocorticoid mediated signaling pathway+++GO:0048812///neuron projection morphogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051726///regulation of cell cycle+++GO:1904045///cellular response to aldosterone 20394 20394 'Scg5' mRNA 2270 2371 2331 112.91 116.43 122.75 16.72 19.42 17.08 117.3633333 17.74 385 438 383 2324 402 6.27E-171 -2.5432057 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0030141///secretory granule GO:0004857///enzyme inhibitor activity+++GO:0030234///enzyme regulator activity+++GO:0051082///unfolded protein binding GO:0006886///intracellular protein transport+++GO:0007218///neuropeptide signaling pathway+++GO:0016486///peptide hormone processing+++GO:0043086///negative regulation of catalytic activity+++GO:0046883///regulation of hormone secretion+++GO:0050790///regulation of catalytic activity 20397 20397 'Sgpl1' mRNA 1827 1893 1788 24.17 24.63 25.19 58.46 55.26 55.18 24.66333333 56.3 5078 4705 4660 1836 4814.333333 1.99E-114 1.378633242 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0008117///sphinganine-1-phosphate aldolase activity+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding GO:0001553///luteinization+++GO:0001570///vasculogenesis+++GO:0001667///ameboidal-type cell migration+++GO:0001822///kidney development+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006807///nitrogen compound metabolic process+++GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0010761///fibroblast migration+++GO:0019752///carboxylic acid metabolic process+++GO:0030097///hemopoiesis+++GO:0030149///sphingolipid catabolic process+++GO:0033327///Leydig cell differentiation+++GO:0040014///regulation of multicellular organism growth+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0097190///apoptotic signaling pathway 20399 20399 'Sh2b1' mRNA 1774 1854 1376 30.28 31.09 25.11 18.19 20.36 18.11 28.82666667 18.88666667 1224 1305 1184 1668 1237.666667 6.43E-06 -0.435953934 04722///Neurotrophin signaling pathway GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding+++GO:0035591///signaling adaptor activity GO:0006928///movement of cell or subcellular component+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0035556///intracellular signal transduction+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:2000278///regulation of DNA biosynthetic process 20400 20400 'Sh2d1a' mRNA 0 1 0 0 0.12 0 0.31 0.14 0.22 0.04 0.223333333 4 2 2 0.333333333 2.666666667 0.249764048 2.877086014 04650///Natural killer cell mediated cytotoxicity GO:0005737///cytoplasm GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006959///humoral immune response+++GO:0006968///cellular defense response+++GO:0007267///cell-cell signaling+++GO:0045087///innate immune response+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050776///regulation of immune response+++GO:0050860///negative regulation of T cell receptor signaling pathway 20401 20401 'Sh3bp1' mRNA 392 448 367 8.81 9.83 8.68 18.79 19.06 16.79 9.106666667 18.21333333 964 956 840 402.3333333 920 4.38E-27 1.183745558 GO:0000145///exocyst+++GO:0001891///phagocytic cup+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0042995///cell projection GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding+++GO:0030215///semaphorin receptor binding "GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0016477///cell migration+++GO:0030834///regulation of actin filament depolymerization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034329///cell junction assembly+++GO:0035020///regulation of Rac protein signal transduction+++GO:0043535///regulation of blood vessel endothelial cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0046847///filopodium assembly+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097178///ruffle assembly" 20402 20402 'Zfp106' mRNA 3944 3750 3321 29.86 28.42 29 18.45 18.23 17.79 29.09333333 18.15666667 2731 2656 2602 3671.666667 2663 1.48E-13 -0.472868781 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0001515///opioid peptide activity+++GO:0003723///RNA binding+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding GO:0008286///insulin receptor signaling pathway 20403 20403 'Itsn2' mRNA 1721.95 1747.83 1230.79 23.19 23.33 14.29 13.96 20.08 18.3 20.27 17.44666667 1486 1707.94 1679.87 1566.856667 1624.603333 0.740213982 0.049465399 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0042734///presynaptic membrane+++GO:0097708///intracellular vesicle+++GO:0098793///presynapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0060090///molecular adaptor activity GO:0006897///endocytosis+++GO:0016197///endosomal transport+++GO:0030154///cell differentiation+++GO:0050790///regulation of catalytic activity+++GO:0150007///clathrin-dependent synaptic vesicle endocytosis+++GO:1903861///positive regulation of dendrite extension 20404 20404 'Sh3gl2' mRNA 1632 1714 1671 33.22 34.1 35.87 11.55 9.6 9.81 34.39666667 10.32 659 528 539 1672.333333 575.3333333 4.92E-60 -1.553692537 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097441///basal dendrite+++GO:0098684///photoreceptor ribbon synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding GO:0001933///negative regulation of protein phosphorylation+++GO:0002090///regulation of receptor internalization+++GO:0006897///endocytosis+++GO:0010629///negative regulation of gene expression+++GO:0016191///synaptic vesicle uncoating+++GO:0031175///neuron projection development+++GO:0048488///synaptic vesicle endocytosis+++GO:0060988///lipid tube assembly+++GO:0097484///dendrite extension+++GO:0097749///membrane tubulation+++GO:0097753///membrane bending+++GO:0099050///vesicle scission+++GO:1903527///positive regulation of membrane tubulation+++GO:1905604///negative regulation of maintenance of permeability of blood-brain barrier+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000369///regulation of clathrin-dependent endocytosis 20405 20405 'Sh3gl1' mRNA 1634 1683 1572 44.61 45.31 45.58 59.5 65.42 58.87 45.16666667 61.26333333 2503 2687 2397 1629.666667 2529 7.18E-17 0.623423249 04144///Endocytosis "GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0017124///SH3 domain binding+++GO:0019902///phosphatase binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0051020///GTPase binding GO:0006897///endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis 20408 20408 'Sh3gl3' mRNA 28 27 29 0.85 0.87 1.04 0.55 0.29 0.49 0.92 0.443333333 16 8 17 28 13.66666667 0.075752268 -1.051744955 04144///Endocytosis "GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098845///postsynaptic endosome+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0006897///endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0045666///positive regulation of neuron differentiation+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:2000369///regulation of clathrin-dependent endocytosis 20409 20409 'Ostf1' mRNA 2355.1 2567.74 2444.32 79.69 85.64 87.74 130.11 128.43 127.66 84.35666667 128.7333333 4419 4257.15 4195.69 2455.72 4290.613333 1.14E-35 0.792773407 GO:0005737///cytoplasm GO:0017124///SH3 domain binding GO:0007165///signal transduction 20410 20410 'Sorbs3' mRNA 5538 5452 5048 102.99 100.4 98.86 96.74 97.82 97.86 100.75 97.47333333 5884 5822 5762 5346 5822.666667 0.050138836 0.112594058 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017166///vinculin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0031589///cell-substrate adhesion+++GO:0043410///positive regulation of MAPK cascade+++GO:0051496///positive regulation of stress fiber assembly 20411 20411 'Sorbs1' mRNA 6161 6405 5948 54.12 55.43 55.44 21.32 23.25 21.72 54.99666667 22.09666667 2649 2823 2634 6171.333333 2702 1.93E-87 -1.202146767 03320///PPAR signaling pathway+++04520///Adherens junction+++04910///Insulin signaling pathway GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005899///insulin receptor complex+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0016600///flotillin complex+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031625///ubiquitin protein ligase binding GO:0008286///insulin receptor signaling pathway+++GO:0031589///cell-substrate adhesion+++GO:0032869///cellular response to insulin stimulus+++GO:0043149///stress fiber assembly+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0046326///positive regulation of glucose import+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048041///focal adhesion assembly+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904393///regulation of skeletal muscle acetylcholine-gated channel clustering 20415 20415 'Shbg' mRNA 24 23 19 0.76 0.71 0.63 0.47 1.02 1 0.7 0.83 23 32 31 22 28.66666667 0.528445222 0.376259381 GO:0005576///extracellular region GO:0005496///steroid binding+++GO:0008289///lipid binding GO:0007285///primary spermatocyte growth 20416 20416 'Shc1' mRNA 2145 2280 2161 35.08 36.94 37.67 58.08 57.24 56.35 36.56333333 57.22333333 4070 3942 3879 2195.333333 3963.666667 6.40E-42 0.840397885 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05100///Bacterial invasion of epithelial cells+++05206///MicroRNAs in cancer+++05214///Glioma+++05220///Chronic myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0070435///Shc-EGFR complex GO:0001784///phosphotyrosine residue binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005158///insulin receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046875///ephrin receptor binding+++GO:0048408///epidermal growth factor binding+++GO:0051219///phosphoprotein binding+++GO:0051721///protein phosphatase 2A binding "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007507///heart development+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0016525///negative regulation of angiogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042127///regulation of cell proliferation+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0090322///regulation of superoxide metabolic process+++GO:0098609///cell-cell adhesion+++GO:1990839///response to endothelin" 20418 20418 'Shc3' mRNA 180 174 138 0.8 0.75 0.65 0.29 0.17 0.2 0.733333333 0.22 76 43 49 164 56 3.06E-09 -1.561574442 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05100///Bacterial invasion of epithelial cells+++05214///Glioma+++05220///Chronic myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005886///plasma membrane+++GO:0045202///synapse GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding "GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007417///central nervous system development+++GO:0007611///learning or memory+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035556///intracellular signal transduction" 20419 20419 'Shcbp1' mRNA 6 6 2 0.16 0.15 0.06 4.01 4.31 3.79 0.123333333 4.036666667 177 186 162 4.666666667 175 6.13E-30 5.221635014 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0005515///protein binding+++GO:0042169///SH2 domain binding GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:2000177///regulation of neural precursor cell proliferation 20420 20420 'Shd' mRNA 162 213 154 6.21 8.02 6.27 4.31 3.52 4.62 6.833333333 4.15 129 104 135 176.3333333 122.6666667 0.019322991 -0.532155923 GO:0005575///cellular_component GO:0001784///phosphotyrosine residue binding 20422 20422 'Sem1' mRNA 1635 1486 1743 285.61 259.8 323.31 449.43 496.98 470.99 289.5733333 472.4666667 2924 3136 2947 1621.333333 3002.333333 9.40E-23 0.8740309 03050///Proteasome+++03440///Homologous recombination+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0032039///integrator complex+++GO:0032991///protein-containing complex" GO:0005515///protein binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006406///mRNA export from nucleus+++GO:0043248///proteasome assembly 20425 20425 'Shmt1' mRNA 12.25 26 22.12 0.25 0.62 0.57 2.65 2.52 2.6 0.48 2.59 128.62 112 116.7 20.12333333 119.1066667 5.51E-14 2.555282316 "00260///Glycine, serine and threonine metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00670///One carbon pool by folate+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors+++01523///Antifolate resistance" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003824///catalytic activity+++GO:0004372///glycine hydroxymethyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008732///L-allo-threonine aldolase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0036094///small molecule binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0050897///cobalt ion binding+++GO:0070905///serine binding" GO:0006231///dTMP biosynthetic process+++GO:0006544///glycine metabolic process+++GO:0006545///glycine biosynthetic process+++GO:0006563///L-serine metabolic process+++GO:0006565///L-serine catabolic process+++GO:0006730///one-carbon metabolic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0017148///negative regulation of translation+++GO:0019264///glycine biosynthetic process from serine+++GO:0035999///tetrahydrofolate interconversion+++GO:0046653///tetrahydrofolate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0051289///protein homotetramerization+++GO:1904482///cellular response to tetrahydrofolate+++GO:1990830///cellular response to leukemia inhibitory factor 20429 20429 'Shox2' mRNA 12 7 9 0.24 0.23 0.37 0.2 0.18 0.12 0.28 0.166666667 10 7 6 9.333333333 7.666666667 0.792924276 -0.299819729 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0002027///regulation of heart rate+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0002063///chondrocyte development+++GO:0003163///sinoatrial node development+++GO:0003170///heart valve development+++GO:0003172///sinoatrial valve development+++GO:0003209///cardiac atrium morphogenesis+++GO:0003213///cardiac right atrium morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030326///embryonic limb morphogenesis+++GO:0032330///regulation of chondrocyte differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0050772///positive regulation of axonogenesis+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0060415///muscle tissue morphogenesis+++GO:0060920///cardiac pacemaker cell differentiation+++GO:0060931///sinoatrial node cell development+++GO:2000172///regulation of branching morphogenesis of a nerve" 20430 20430 'Cyfip1' mRNA 2700.64 2835.53 2778.23 33.04 34.03 36.06 54.2 49.54 48.23 34.37666667 50.65666667 5120.11 4550.7 4393.14 2771.466667 4687.983333 2.56E-27 0.744679418 04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005831///steroid hormone aporeceptor complex+++GO:0005845///mRNA cap binding complex+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0031252///cell leading edge+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0045171///intercellular bridge+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0090724///central region of growth cone+++GO:0090725///peripheral region of growth cone+++GO:0098794///postsynapse+++GO:1990904///ribonucleoprotein complex GO:0000340///RNA 7-methylguanosine cap binding+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031267///small GTPase binding+++GO:0045182///translation regulator activity+++GO:0051015///actin filament binding "GO:0000902///cell morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0030154///cell differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:0031175///neuron projection development+++GO:0031529///ruffle organization+++GO:0031641///regulation of myelination+++GO:0032869///cellular response to insulin stimulus+++GO:0042981///regulation of apoptotic process+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048675///axon extension+++GO:0050772///positive regulation of axonogenesis+++GO:0050890///cognition+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0051602///response to electrical stimulus+++GO:0071391///cellular response to estrogen stimulus+++GO:0097484///dendrite extension+++GO:0099563///modification of synaptic structure+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:1900006///positive regulation of dendrite development+++GO:1900029///positive regulation of ruffle assembly+++GO:1903422///negative regulation of synaptic vesicle recycling+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation" 20431 20431 'Pmel' mRNA 797.29 812.89 839 20.87 20.89 23.5 13.02 13.65 12.35 21.75333333 13.00666667 571.2 578.11 526.1 816.3933333 558.47 2.09E-07 -0.560821073 GO:0005576///extracellular region+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032585///multivesicular body membrane+++GO:0042470///melanosome GO:0042802///identical protein binding GO:0032438///melanosome organization+++GO:0042438///melanin biosynthetic process+++GO:0048023///positive regulation of melanin biosynthetic process 20437 20437 'Siah1a' mRNA 319.08 343.9 259.56 5.75 5.42 4.44 4.12 3.34 3.47 5.203333333 3.643333333 264.65 214.7 228.15 307.5133333 235.8333333 0.020521774 -0.392246452 04013///MAPK signaling pathway - fly+++04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030877///beta-catenin destruction complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097718///disordered domain specific binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007141///male meiosis I+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009791///post-embryonic development+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0030163///protein catabolic process+++GO:0031648///protein destabilization+++GO:0040014///regulation of multicellular organism growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051402///neuron apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 20438 20438 'Siah1b' mRNA 138.09 142 125 4.07 4.08 3.81 3.49 3.69 3.88 3.986666667 3.686666667 139.96 136 137.52 135.03 137.8266667 0.960903326 0.014669204 04013///MAPK signaling pathway - fly+++04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030877///beta-catenin destruction complex GO:0004842///ubiquitin-protein transferase activity+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031648///protein destabilization+++GO:0043065///positive regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051402///neuron apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 20439 20439 'Siah2' mRNA 95 72 57 2.13 1.59 1.35 2.2 2.47 2.33 1.69 2.333333333 113 124 116 74.66666667 117.6666667 0.019695006 0.650950468 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0031396///regulation of protein ubiquitination+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044257///cellular protein catabolic process+++GO:0048511///rhythmic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 20440 20440 'St6gal1' mRNA 2330 2330 2309 28.42 28.16 30.2 27.8 29.06 27.26 28.92666667 28.04 2646 2693 2511 2323 2616.666667 0.033174174 0.159549776 00510///N-Glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003835///beta-galactoside alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042803///protein homodimerization activity" GO:0006054///N-acetylneuraminate metabolic process+++GO:0006486///protein glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0032946///positive regulation of mononuclear cell proliferation+++GO:0050922///negative regulation of chemotaxis+++GO:0097503///sialylation+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1990743///protein sialylation+++GO:2000110///negative regulation of macrophage apoptotic process 20441 20441 'St3gal3' mRNA 132 99 98 3.32 2.37 2.55 2.05 1.65 1.97 2.746666667 1.89 96 79 90 109.6666667 88.33333333 0.267372796 -0.323247458 00513///Various types of N-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0008118///N-acetyllactosaminide alpha-2,3-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0010706///ganglioside biosynthetic process via lactosylceramide+++GO:0097503///sialylation 20442 20442 'St3gal1' mRNA 319 315.04 248 2.92 2.83 2.41 2.19 1.88 1.96 2.72 2.01 277 232 239 294.0133333 249.3333333 0.163056572 -0.246554758 00512///Mucin type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00604///Glycosphingolipid biosynthesis - ganglio series GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0032588///trans-Golgi network membrane+++GO:1990675///Golgi medial cisterna membrane+++GO:1990676///Golgi trans cisterna membrane "GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047288///monosialoganglioside sialyltransferase activity" "GO:0002319///memory B cell differentiation+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0006468///protein phosphorylation+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006629///lipid metabolic process+++GO:0010706///ganglioside biosynthetic process via lactosylceramide+++GO:0097503///sialylation+++GO:1905403///negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process+++GO:1990743///protein sialylation" 20443 20443 'St3gal4' mRNA 2564.42 2578.74 2696.01 50.85 50.89 60.73 46.05 44.91 45.19 54.15666667 45.38333333 2831.95 2628.74 2647.88 2613.056667 2702.856667 0.737100838 0.034117764 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0004513///neolactotetraosylceramide alpha-2,3-sialyltransferase activity+++GO:0008118///N-acetyllactosaminide alpha-2,3-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047288///monosialoganglioside sialyltransferase activity" GO:0006486///protein glycosylation+++GO:0006629///lipid metabolic process+++GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0030194///positive regulation of blood coagulation+++GO:0030259///lipid glycosylation+++GO:0050890///cognition+++GO:0097503///sialylation+++GO:1903238///positive regulation of leukocyte tethering or rolling+++GO:1990743///protein sialylation 20444 20444 'St3gal2' mRNA 322.24 318.51 346.4 3.09 2.97 3.53 4.88 5.34 5.32 3.196666667 5.18 587.1 627.09 619.67 329.05 611.2866667 2.37E-12 0.881405534 00512///Mucin type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042803///protein homodimerization activity+++GO:0047288///monosialoganglioside sialyltransferase activity" GO:0006486///protein glycosylation+++GO:0006629///lipid metabolic process+++GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0010706///ganglioside biosynthetic process via lactosylceramide+++GO:0010707///globoside biosynthetic process via lactosylceramide+++GO:0030259///lipid glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation 20445 20445 'St6galnac1' mRNA 3 3 2 0.07 0.07 0.05 0.08 0.04 0.02 0.063333333 0.046666667 4 2 1 2.666666667 2.333333333 0.917322082 -0.205099574 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0009312///oligosaccharide biosynthetic process+++GO:0097503///sialylation 20446 20446 'St6galnac2' mRNA 732 733 643 20.46 20.19 19.07 21.45 21.02 20.35 19.90666667 20.94 882 844 810 702.6666667 845.3333333 0.011124445 0.256624944 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation 20447 20447 'St6galnac3' mRNA 391.96 387.73 346.33 4.85 4.66 3.99 0.99 0.66 1.02 4.5 0.89 123.3 91.91 107.22 375.34 107.4766667 5.31E-27 -1.819725699 00512///Mucin type O-glycan biosynthesis+++00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047290///(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006677///glycosylceramide metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0009100///glycoprotein metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation 20448 20448 'St6galnac4' mRNA 354 323 417 5.08 4.53 6.37 15.81 16.61 15.98 5.326666667 16.13333333 1262 1298 1241 364.6666667 1267 2.59E-51 1.780238344 00512///Mucin type O-glycan biosynthesis+++00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047290///(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation 20449 20449 'St8sia1' mRNA 360.45 335.49 257.04 1.29 1.22 1.01 0.95 0.89 0.84 1.173333333 0.893333333 265.01 233.5 221.51 317.66 240.0066667 0.016152934 -0.412500434 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009311///oligosaccharide metabolic process+++GO:0034605///cellular response to heat+++GO:0097503///sialylation 20450 20450 'St8sia2' mRNA 6613 6812 6636 65.53 66.37 69.75 11.13 10.22 10.16 67.21666667 10.50333333 1293 1160 1143 6687 1198.666667 0 -2.493188558 GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0005515///protein binding+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0009311///oligosaccharide metabolic process+++GO:0051965///positive regulation of synapse assembly+++GO:0097503///sialylation+++GO:1901216///positive regulation of neuron death+++GO:1990138///neuron projection extension 20451 20451 'St8sia3' mRNA 172 192 182 1.52 1.67 1.71 0.08 0.14 0.06 1.633333333 0.093333333 10 18 7 182 11.66666667 6.42E-31 -3.974183518 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042802///identical protein binding" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0009100///glycoprotein metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation+++GO:1990743///protein sialylation 20452 20452 'St8sia4' mRNA 1713.41 1630.73 1298.06 9.38 8.71 7.58 6.29 5.5 5.91 8.556666667 5.9 1126.4 888.53 995.35 1547.4 1003.426667 3.86E-10 -0.63399823 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation 20454 20454 'St3gal5' mRNA 4944 5148 2851 121.8 124.83 74.33 30.98 36 34.56 106.9866667 33.84666667 1430 1632 1560 4314.333333 1540.666667 1.65E-10 -1.482842585 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047291///lactosylceramide alpha-2,3-sialyltransferase activity" GO:0006486///protein glycosylation+++GO:0097503///sialylation 20459 20459 'Ptk6' mRNA 1 2 1 0.02 0.05 0.03 0.17 0.09 0.18 0.033333333 0.146666667 8 4 8 1.333333333 6.666666667 0.108142129 2.312112208 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0045087///innate immune response+++GO:0045926///negative regulation of growth+++GO:0046777///protein autophosphorylation+++GO:0060575///intestinal epithelial cell differentiation+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0071300///cellular response to retinoic acid 20460 20460 'Stil' mRNA 1 2 4 0.01 0.02 0.05 0.96 0.54 0.83 0.026666667 0.776666667 110 60 93 2.333333333 87.66666667 5.73E-15 5.211333375 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0000578///embryonic axis specification+++GO:0001701///in utero embryonic development+++GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0007052///mitotic spindle organization+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0021915///neural tube development+++GO:0030900///forebrain development+++GO:0030903///notochord development+++GO:0033504///floor plate development+++GO:0035264///multicellular organism growth+++GO:0043066///negative regulation of apoptotic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0046599///regulation of centriole replication+++GO:0051298///centrosome duplication+++GO:0071174///mitotic spindle checkpoint+++GO:0071539///protein localization to centrosome+++GO:1905515///non-motile cilium assembly 20462 20462 'Tra2b' mRNA 3328 3581 3087 64.66 68.88 64 68.56 64.43 66.86 65.84666667 66.61666667 4012 3727 3799 3332 3846 0.001574244 0.19668552 03040///Spliceosome+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0036002///pre-mRNA binding+++GO:0042802///identical protein binding+++GO:0070717///poly-purine tract binding "GO:0000302///response to reactive oxygen species+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0021796///cerebral cortex regionalization+++GO:0043484///regulation of RNA splicing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0071333///cellular response to glucose stimulus+++GO:1990403///embryonic brain development" 20463 20463 'Cox7a2l' mRNA 2473 2474 2313 143.73 142.16 142.66 126.34 121.67 132.2 142.85 126.7366667 2493 2341 2521 2420 2451.666667 0.933678125 0.007441041 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004129///cytochrome-c oxidase activity+++GO:0009055///electron transfer activity "GO:0002082///regulation of oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0097250///mitochondrial respiratory chain supercomplex assembly" 20466 20466 'Sin3a' mRNA 1043 1133 1058 10.99 11.75 11.82 7.88 7.77 8.26 11.52 7.97 867 827 879 1078 857.6666667 2.02E-04 -0.34166548 04919///Thyroid hormone signaling pathway+++05016///Huntington disease+++05169///Epstein-Barr virus infection+++05202///Transcriptional misregulation in cancer GO:0000118///histone deacetylase complex+++GO:0000776///kinetochore+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0016580///Sin3 complex+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0044877///protein-containing complex binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006476///protein deacetylation+++GO:0007568///aging+++GO:0010243///response to organonitrogen compound+++GO:0010817///regulation of hormone levels+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016575///histone deacetylation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030516///regulation of axon extension+++GO:0031937///positive regulation of chromatin silencing+++GO:0034613///cellular protein localization+++GO:0042754///negative regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0045666///positive regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0051595///response to methylglyoxal+++GO:0071333///cellular response to glucose stimulus+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1901675///negative regulation of histone H3-K27 acetylation+++GO:1903351///cellular response to dopamine+++GO:2000678///negative regulation of transcription regulatory region DNA binding" 20467 20467 'Sin3b' mRNA 1296 1309 1148 51.55 50.76 51.46 101.94 99.3 94.86 51.25666667 98.7 2258 2101 2019 1251 2126 1.10E-24 0.754679464 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0000805///X chromosome+++GO:0000806///Y chromosome+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016580///Sin3 complex+++GO:0030849///autosome GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007519///skeletal muscle tissue development+++GO:0016575///histone deacetylation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048738///cardiac muscle tissue development" 20469 20469 'Sipa1' mRNA 297 349 369 4.38 5.04 5.76 14.88 13.63 14.32 5.06 14.27666667 1166 1045 1082 338.3333333 1097.666667 1.05E-48 1.682579502 04015///Rap1 signaling pathway+++04670///Leukocyte transendothelial migration GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005096///GTPase activator activity+++GO:0008022///protein C-terminus binding GO:0042631///cellular response to water deprivation+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0051726///regulation of cell cycle+++GO:0090630///activation of GTPase activity 20471 20471 'Six1' mRNA 3315 3275 3162 64.15 62.38 64.91 31.71 31.66 32.42 63.81333333 31.93 1885 1838 1866 3250.666667 1863 2.66E-38 -0.814865053 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001759///organ induction+++GO:0001822///kidney development+++GO:0003151///outflow tract morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007382///specification of segmental identity, maxillary segment+++GO:0007389///pattern specification process+++GO:0007519///skeletal muscle tissue development+++GO:0007605///sensory perception of sound+++GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0014033///neural crest cell differentiation+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0014857///regulation of skeletal muscle cell proliferation+++GO:0021610///facial nerve morphogenesis+++GO:0022008///neurogenesis+++GO:0030855///epithelial cell differentiation+++GO:0030878///thyroid gland development+++GO:0030910///olfactory placode formation+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0035909///aorta morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043586///tongue development+++GO:0045664///regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048538///thymus development+++GO:0048665///neuron fate specification+++GO:0048699///generation of neurons+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048741///skeletal muscle fiber development+++GO:0048839///inner ear development+++GO:0048856///anatomical structure development+++GO:0050678///regulation of epithelial cell proliferation+++GO:0051451///myoblast migration+++GO:0060037///pharyngeal system development+++GO:0061055///myotome development+++GO:0061197///fungiform papilla morphogenesis+++GO:0061551///trigeminal ganglion development+++GO:0071599///otic vesicle development+++GO:0072075///metanephric mesenchyme development+++GO:0072095///regulation of branch elongation involved in ureteric bud branching+++GO:0072107///positive regulation of ureteric bud formation+++GO:0072172///mesonephric tubule formation+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0072513///positive regulation of secondary heart field cardioblast proliferation+++GO:0086100///endothelin receptor signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:1905243///cellular response to 3,3',5-triiodo-L-thyronine+++GO:2000729///positive regulation of mesenchymal cell proliferation involved in ureter development+++GO:2001014///regulation of skeletal muscle cell differentiation" 20472 20472 'Six2' mRNA 733 664 681 20.44 18.9 20.74 11.81 12.13 12.02 20.02666667 11.98666667 481 483 468 692.6666667 477.3333333 8.92E-07 -0.54928687 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001656///metanephros development+++GO:0001822///kidney development+++GO:0002062///chondrocyte differentiation+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0007275///multicellular organism development+++GO:0007501///mesodermal cell fate specification+++GO:0008283///cell proliferation+++GO:0009948///anterior/posterior axis specification+++GO:0016477///cell migration+++GO:0030278///regulation of ossification+++GO:0032330///regulation of chondrocyte differentiation+++GO:0042474///middle ear morphogenesis+++GO:0045596///negative regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0072006///nephron development+++GO:0072028///nephron morphogenesis+++GO:0072038///mesenchymal stem cell maintenance involved in nephron morphogenesis+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0072161///mesenchymal cell differentiation involved in kidney development+++GO:0090189///regulation of branching involved in ureteric bud morphogenesis+++GO:0097168///mesenchymal stem cell proliferation+++GO:1902732///positive regulation of chondrocyte proliferation" 20474 20474 'Six4' mRNA 1139 1238 770 10.46 11.21 7.07 3.46 3.47 3.73 9.58 3.553333333 463 435 467 1049 455 7.02E-20 -1.207759286 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007519///skeletal muscle tissue development+++GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0008584///male gonad development+++GO:0010468///regulation of gene expression+++GO:0030238///male sex determination+++GO:0030910///olfactory placode formation+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0042472///inner ear morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043586///tongue development+++GO:0045214///sarcomere organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046661///male sex differentiation+++GO:0048538///thymus development+++GO:0048699///generation of neurons+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048856///anatomical structure development+++GO:0050678///regulation of epithelial cell proliferation+++GO:0051451///myoblast migration+++GO:0060037///pharyngeal system development+++GO:0061055///myotome development+++GO:0061197///fungiform papilla morphogenesis+++GO:0061551///trigeminal ganglion development+++GO:0072075///metanephric mesenchyme development+++GO:0072095///regulation of branch elongation involved in ureteric bud branching+++GO:0072107///positive regulation of ureteric bud formation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0098528///skeletal muscle fiber differentiation+++GO:1902725///negative regulation of satellite cell differentiation" 20475 20475 'Six5' mRNA 754.88 689.76 583.94 14.52 13.05 11.91 5.08 4.98 5.01 13.16 5.023333333 303.63 290.86 290 676.1933333 294.83 8.74E-23 -1.206532593 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding" "GO:0002088///lens development in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007286///spermatid development+++GO:0008285///negative regulation of cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation" 20476 20476 'Six6' mRNA 2 0 0 0.03 0 0 0 0.01 0.01 0.01 0.006666667 0 1 1 0.666666667 0.666666667 0.998591786 0.024030876 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development" 20479 20479 'Vps4b' mRNA 1281 1432 1397 21.38 23.52 24.73 23.54 24.87 23.95 23.21 24.12 1623 1675 1599 1370 1632.333333 0.00710804 0.240234195 04144///Endocytosis+++04217///Necroptosis GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0090543///Flemming body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0006813///potassium ion transport+++GO:0006997///nucleus organization+++GO:0007032///endosome organization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0019076///viral release from host cell+++GO:0030301///cholesterol transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0032510///endosome to lysosome transport via multivesicular body sorting pathway+++GO:0033993///response to lipid+++GO:0036258///multivesicular body assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0046761///viral budding from plasma membrane+++GO:0048524///positive regulation of viral process+++GO:0050792///regulation of viral process+++GO:0051013///microtubule severing+++GO:0051261///protein depolymerization+++GO:0051301///cell division+++GO:0060548///negative regulation of cell death+++GO:0061738///late endosomal microautophagy+++GO:0061952///midbody abscission+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902188///positive regulation of viral release from host cell+++GO:1903542///negative regulation of exosomal secretion+++GO:1903543///positive regulation of exosomal secretion+++GO:1903724///positive regulation of centriole elongation+++GO:1903902///positive regulation of viral life cycle+++GO:1904903///ESCRT III complex disassembly 20480 20480 'Clpb' mRNA 1709.61 1759.17 1672 20.55 20.86 21.36 15.7 15.88 15.68 20.92333333 15.75333333 1514.18 1485.99 1444.02 1713.593333 1481.396667 0.003935125 -0.221948942 04213///Longevity regulating pathway - multiple species GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0034605///cellular response to heat+++GO:0039529///RIG-I signaling pathway 20481 20481 'Ski' mRNA 842 808 737 8.33 7.84 7.74 10.59 9.7 10.4 7.97 10.23 1233 1111 1180 795.6666667 1174.666667 3.98E-10 0.551122693 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0046811///histone deacetylase inhibitor activity+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001843///neural tube closure+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006351///transcription, DNA-templated+++GO:0008285///negative regulation of cell proliferation+++GO:0009948///anterior/posterior axis specification+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0014902///myotube differentiation+++GO:0021772///olfactory bulb development+++GO:0022011///myelination in peripheral nervous system+++GO:0030326///embryonic limb morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031064///negative regulation of histone deacetylation+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0043010///camera-type eye development+++GO:0043388///positive regulation of DNA binding+++GO:0043585///nose morphogenesis+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048593///camera-type eye morphogenesis+++GO:0048741///skeletal muscle fiber development+++GO:0060021///roof of mouth development+++GO:0060041///retina development in camera-type eye+++GO:0060325///face morphogenesis+++GO:0060349///bone morphogenesis+++GO:0060395///SMAD protein signal transduction+++GO:0070208///protein heterotrimerization" 20482 20482 'Skil' mRNA 739 784 757 5.61 5.91 6.24 7.98 7.46 7.76 5.92 7.733333333 1197 1104 1132 760 1144.333333 1.30E-10 0.577781939 04550///Signaling pathways regulating pluripotency of stem cells GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046332///SMAD binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001825///blastocyst formation+++GO:0002260///lymphocyte homeostasis+++GO:0007050///cell cycle arrest+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007519///skeletal muscle tissue development+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0034097///response to cytokine+++GO:0045596///negative regulation of cell differentiation+++GO:0050772///positive regulation of axonogenesis+++GO:0051726///regulation of cell cycle+++GO:0070306///lens fiber cell differentiation+++GO:0070848///response to growth factor+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage 20491 20491 'Sla' mRNA 100 107 79 1.86 1.83 1.49 19.77 19.89 20.58 1.726666667 20.08 1273 1235 1279 95.33333333 1262.333333 2.92E-187 3.718092773 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005925///focal adhesion+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0043197///dendritic spine GO:0004713///protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0030154///cell differentiation+++GO:0045087///innate immune response 20492 20492 'Slbp' mRNA 797 769 814 23.96 22.79 25.97 34.93 40.16 35.63 24.24 36.90666667 1334 1497 1316 793.3333333 1382.333333 7.62E-16 0.788737438 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding+++GO:0071207///histone pre-mRNA stem-loop binding GO:0006397///mRNA processing+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0051028///mRNA transport 20493 20493 'Slc10a1' mRNA 8 10 7.97 0.29 0.36 0.32 0.47 0.41 0.26 0.323333333 0.38 15 12 7.92 8.656666667 11.64 0.670431482 0.433533334 04976///Bile secretion+++05161///Hepatitis B GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008508///bile acid:sodium symporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0010468///regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0015721///bile acid and bile salt transport+++GO:0031667///response to nutrient levels+++GO:0035690///cellular response to drug+++GO:0038183///bile acid signaling pathway+++GO:0045471///response to ethanol+++GO:0055085///transmembrane transport+++GO:0120188///regulation of bile acid secretion+++GO:1904486///response to 17alpha-ethynylestradiol 20494 20494 'Slc10a2' mRNA 1 1 0 0.01 0.01 0 0 0.02 0 0.006666667 0.006666667 0 1.99 0 0.666666667 0.663333333 0.863090843 -0.875251456 04976///Bile secretion GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0008508///bile acid:sodium symporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0009617///response to bacterium+++GO:0015721///bile acid and bile salt transport+++GO:0055085///transmembrane transport 20496 20496 'Slc12a2' mRNA 7764 7936 7266 63.01 63.3 62.54 50.5 43.81 48.07 62.95 47.46 7166 6074 6608 7655.333333 6616 2.55E-04 -0.222632274 04970///Salivary secretion+++04972///Pancreatic secretion+++05110///Vibrio cholerae infection GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0071944///cell periphery GO:0005515///protein binding+++GO:0008511///sodium:potassium:chloride symporter activity+++GO:0008519///ammonium transmembrane transporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006821///chloride transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0006884///cell volume homeostasis+++GO:0006972///hyperosmotic response+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007568///aging+++GO:0010818///T cell chemotaxis+++GO:0015696///ammonium transport+++GO:0015698///inorganic anion transport+++GO:0030001///metal ion transport+++GO:0030007///cellular potassium ion homeostasis+++GO:0030321///transepithelial chloride transport+++GO:0030644///cellular chloride ion homeostasis+++GO:0035264///multicellular organism growth+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0035725///sodium ion transmembrane transport+++GO:0035865///cellular response to potassium ion+++GO:0045795///positive regulation of cell volume+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060763///mammary duct terminal end bud growth+++GO:0061044///negative regulation of vascular wound healing+++GO:0070634///transepithelial ammonium transport+++GO:0071805///potassium ion transmembrane transport+++GO:0072488///ammonium transmembrane transport+++GO:0098658///inorganic anion import across plasma membrane+++GO:0098659///inorganic cation import across plasma membrane+++GO:0098719///sodium ion import across plasma membrane+++GO:0150003///regulation of spontaneous synaptic transmission+++GO:1902476///chloride transmembrane transport+++GO:1904450///positive regulation of aspartate secretion+++GO:1904464///regulation of matrix metallopeptidase secretion+++GO:1990573///potassium ion import across plasma membrane+++GO:1990869///cellular response to chemokine 20498 20498 'Slc12a4' mRNA 1528 1524 1646 21.61 21.2 24.7 29.48 29.22 27.21 22.50333333 28.63666667 2399 2323 2145 1566 2289 2.31E-10 0.532867666 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006884///cell volume homeostasis+++GO:0007268///chemical synaptic transmission+++GO:0015698///inorganic anion transport+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 20499 20499 'Slc12a7' mRNA 1701 1697 1690 17.75 17.52 18.82 19.5 16.77 17.75 18.03 18.00666667 2143 1801 1895 1696 1946.333333 0.030201739 0.184656345 04966///Collecting duct acid secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0008519///ammonium transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006884///cell volume homeostasis+++GO:0007268///chemical synaptic transmission+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0140157///ammonium import across plasma membrane+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 20500 20500 'Slc13a2' mRNA 1 0 0 0.04 0 0 0.1 0.1 0.14 0.013333333 0.113333333 3 3 4 0.333333333 3.333333333 0.157919443 3.206896272 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015141///succinate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0098656///anion transmembrane transport 20501 20501 'Slc16a1' mRNA 1077 1077 1099 13.06 12.84 14.13 10.29 10.91 9.48 13.34333333 10.22666667 977 1012 872 1084.333333 953.6666667 0.05878018 -0.198090596 GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0097159///organic cyclic compound binding GO:0006629///lipid metabolic process+++GO:0007098///centrosome cycle+++GO:0015718///monocarboxylic acid transport+++GO:0032094///response to food+++GO:0035873///lactate transmembrane transport+++GO:0035879///plasma membrane lactate transport+++GO:0042593///glucose homeostasis+++GO:0050796///regulation of insulin secretion+++GO:0051780///behavioral response to nutrient+++GO:0055085///transmembrane transport+++GO:0071407///cellular response to organic cyclic compound+++GO:1905039///carboxylic acid transmembrane transport 20502 20502 'Slc16a2' mRNA 1940 2036 1863 25.08 25.9 25.59 38.62 38.97 36.73 25.52333333 38.10666667 3432 3384 3163 1946.333333 3326.333333 6.88E-32 0.762141282 04919///Thyroid hormone signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006520///cellular amino acid metabolic process+++GO:0006590///thyroid hormone generation+++GO:0009914///hormone transport+++GO:0042403///thyroid hormone metabolic process+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:0070460///thyroid-stimulating hormone secretion+++GO:0089718///amino acid import across plasma membrane+++GO:2000178///negative regulation of neural precursor cell proliferation 20503 20503 'Slc16a7' mRNA 139 151 167.08 1.65 1.96 2.95 4.42 3.55 3.67 2.186666667 3.88 303 227 243 152.36 257.6666667 1.31E-04 0.740746119 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0050833///pyruvate transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0035873///lactate transmembrane transport+++GO:0035879///plasma membrane lactate transport+++GO:0055085///transmembrane transport+++GO:1901475///pyruvate transmembrane transport 20505 20505 'Slc34a1' mRNA 0 2 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 "04928///Parathyroid hormone synthesis, secretion and action+++04978///Mineral absorption" GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016607///nuclear speck+++GO:0031226///intrinsic component of plasma membrane+++GO:0031526///brush border membrane+++GO:0031982///vesicle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle GO:0005436///sodium:phosphate symporter activity+++GO:0005515///protein binding+++GO:0015136///sialic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0001503///ossification+++GO:0001822///kidney development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0006820///anion transport+++GO:0007584///response to nutrient+++GO:0009100///glycoprotein metabolic process+++GO:0010288///response to lead ion+++GO:0015739///sialic acid transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0032026///response to magnesium ion+++GO:0032355///response to estradiol+++GO:0033189///response to vitamin A+++GO:0035435///phosphate ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0035864///response to potassium ion+++GO:0042431///indole metabolic process+++GO:0042493///response to drug+++GO:0043434///response to peptide hormone+++GO:0044341///sodium-dependent phosphate transport+++GO:0045838///positive regulation of membrane potential+++GO:0046686///response to cadmium ion+++GO:0046689///response to mercury ion+++GO:0046849///bone remodeling+++GO:0055062///phosphate ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060416///response to growth hormone+++GO:0071107///response to parathyroid hormone+++GO:0071248///cellular response to metal ion+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0072350///tricarboxylic acid metabolic process+++GO:0072734///cellular response to staurosporine+++GO:0097066///response to thyroid hormone+++GO:0097187///dentinogenesis+++GO:0098719///sodium ion import across plasma membrane+++GO:1901128///gentamycin metabolic process+++GO:1901652///response to peptide+++GO:1901684///arsenate ion transmembrane transport+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:2000187///positive regulation of phosphate transmembrane transport 20509 20509 'Slc19a1' mRNA 951 1013 927 22.96 24.19 24.03 24.32 24.88 23.57 23.72666667 24.25666667 1159 1146 1094 963.6666667 1133 0.01400947 0.222474251 01523///Antifolate resistance+++04977///Vitamin digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005542///folic acid binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0008517///folic acid transmembrane transporter activity+++GO:0008518///folate:anion antiporter activity+++GO:0015297///antiporter activity+++GO:0015350///methotrexate transmembrane transporter activity+++GO:0061507///cyclic-GMP-AMP binding+++GO:0090482///vitamin transmembrane transporter activity GO:0007565///female pregnancy+++GO:0015711///organic anion transport+++GO:0015884///folic acid transport+++GO:0035461///vitamin transmembrane transport+++GO:0051180///vitamin transport+++GO:0051503///adenine nucleotide transport+++GO:0051958///methotrexate transport+++GO:0055085///transmembrane transport+++GO:0098838///folate transmembrane transport+++GO:1903790///guanine nucleotide transmembrane transport+++GO:1904447///folate import across plasma membrane 20510 20510 'Slc1a1' mRNA 32 26 23 0.46 0.37 0.35 0.71 0.89 0.77 0.393333333 0.79 56 69 59 27 61.33333333 0.002326907 1.176742488 04721///Synaptic vesicle cycle+++04724///Glutamatergic synapse+++04974///Protein digestion and absorption GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0032279///asymmetric synapse+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0071944///cell periphery+++GO:0097386///glial cell projection+++GO:0097440///apical dendrite+++GO:0098793///presynapse+++GO:0099544///perisynaptic space+++GO:0150002///distal dendrite+++GO:1990635///proximal dendrite GO:0005253///anion channel activity+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005314///high-affinity glutamate transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015108///chloride transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015501///glutamate:sodium symporter activity+++GO:0016595///glutamate binding+++GO:0033229///cysteine transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0140010///D-aspartate transmembrane transporter activity GO:0001662///behavioral fear response+++GO:0001816///cytokine production+++GO:0001932///regulation of protein phosphorylation+++GO:0001975///response to amphetamine+++GO:0002027///regulation of heart rate+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006801///superoxide metabolic process+++GO:0006865///amino acid transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007212///dopamine receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007420///brain development+++GO:0007611///learning or memory+++GO:0007613///memory+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0010460///positive regulation of heart rate+++GO:0010467///gene expression+++GO:0010842///retina layer formation+++GO:0015813///L-glutamate transmembrane transport+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0022008///neurogenesis+++GO:0030534///adult behavior+++GO:0032148///activation of protein kinase B activity+++GO:0034599///cellular response to oxidative stress+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0036293///response to decreased oxygen levels+++GO:0036475///neuron death in response to oxidative stress+++GO:0042417///dopamine metabolic process+++GO:0042493///response to drug+++GO:0042883///cysteine transport+++GO:0043278///response to morphine+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045184///establishment of protein localization+++GO:0048514///blood vessel morphogenesis+++GO:0048678///response to axon injury+++GO:0050808///synapse organization+++GO:0051938///L-glutamate import+++GO:0055085///transmembrane transport+++GO:0060013///righting reflex+++GO:0060041///retina development in camera-type eye+++GO:0060047///heart contraction+++GO:0060291///long-term synaptic potentiation+++GO:0061744///motor behavior+++GO:0070777///D-aspartate transport+++GO:0070778///L-aspartate transmembrane transport+++GO:0070779///D-aspartate import across plasma membrane+++GO:0070997///neuron death+++GO:0071242///cellular response to ammonium ion+++GO:0071288///cellular response to mercury ion+++GO:0071314///cellular response to cocaine+++GO:0071407///cellular response to organic cyclic compound+++GO:0071577///zinc ion transmembrane transport+++GO:0072347///response to anesthetic+++GO:0090313///regulation of protein targeting to membrane+++GO:0090461///glutamate homeostasis+++GO:0097049///motor neuron apoptotic process+++GO:0098712///L-glutamate import across plasma membrane+++GO:0098877///neurotransmitter receptor transport to plasma membrane+++GO:0140009///L-aspartate import across plasma membrane+++GO:1902476///chloride transmembrane transport+++GO:1903712///cysteine transmembrane transport+++GO:1903926///cellular response to bisphenol A+++GO:1990708///conditioned place preference 20511 20511 'Slc1a2' mRNA 901 900 806 6.44 5.78 6.18 7.14 6.94 8.16 6.133333333 7.413333333 1188 1077 1194 869 1153 8.00E-06 0.39732157 04721///Synaptic vesicle cycle+++04724///Glutamatergic synapse+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030673///axolemma+++GO:0031982///vesicle+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044297///cell body+++GO:0044306///neuron projection terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0097449///astrocyte projection+++GO:0098796///membrane protein complex+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005314///high-affinity glutamate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015501///glutamate:sodium symporter activity+++GO:0033229///cysteine transmembrane transporter activity+++GO:0046872///metal ion binding GO:0006750///glutathione biosynthetic process+++GO:0006865///amino acid transport+++GO:0007399///nervous system development+++GO:0007632///visual behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0009416///response to light stimulus+++GO:0009611///response to wounding+++GO:0010259///multicellular organism aging+++GO:0015813///L-glutamate transmembrane transport+++GO:0021537///telencephalon development+++GO:0030534///adult behavior+++GO:0031668///cellular response to extracellular stimulus+++GO:0035264///multicellular organism growth+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0046326///positive regulation of glucose import+++GO:0055085///transmembrane transport+++GO:0070207///protein homotrimerization+++GO:0070778///L-aspartate transmembrane transport+++GO:0070779///D-aspartate import across plasma membrane+++GO:0071314///cellular response to cocaine+++GO:0098656///anion transmembrane transport+++GO:0098712///L-glutamate import across plasma membrane+++GO:0098810///neurotransmitter reuptake+++GO:1903712///cysteine transmembrane transport 20512 20512 'Slc1a3' mRNA 16065 17153 16698 203.88 213.95 224.71 122.41 116.79 116.36 214.18 118.52 11096 10324 10205 16638.66667 10541.66667 4.38E-33 -0.67182792 04721///Synaptic vesicle cycle+++04724///Glutamatergic synapse+++05016///Huntington disease GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0071944///cell periphery+++GO:0098796///membrane protein complex GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005314///high-affinity glutamate transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015172///acidic amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015501///glutamate:sodium symporter activity+++GO:0016595///glutamate binding+++GO:0016597///amino acid binding+++GO:0046872///metal ion binding GO:0006865///amino acid transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0007605///sensory perception of sound+++GO:0009410///response to xenobiotic stimulus+++GO:0009416///response to light stimulus+++GO:0009449///gamma-aminobutyric acid biosynthetic process+++GO:0009611///response to wounding+++GO:0010035///response to inorganic substance+++GO:0015813///L-glutamate transmembrane transport+++GO:0021545///cranial nerve development+++GO:0031223///auditory behavior+++GO:0042493///response to drug+++GO:0043200///response to amino acid+++GO:0043490///malate-aspartate shuttle+++GO:0046677///response to antibiotic+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050806///positive regulation of synaptic transmission+++GO:0050885///neuromuscular process controlling balance+++GO:0051938///L-glutamate import+++GO:0055085///transmembrane transport+++GO:0070779///D-aspartate import across plasma membrane+++GO:0071314///cellular response to cocaine+++GO:0071805///potassium ion transmembrane transport+++GO:0098712///L-glutamate import across plasma membrane+++GO:0140009///L-aspartate import across plasma membrane+++GO:1902476///chloride transmembrane transport 20513 20513 'Slc1a6' mRNA 175.03 178.24 166.43 1.83 1.82 1.83 1.19 1.11 1.09 1.826666667 1.13 132.81 117.65 114.68 173.2333333 121.7133333 0.012275578 -0.527774375 04721///Synaptic vesicle cycle+++04724///Glutamatergic synapse+++05017///Spinocerebellar ataxia GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098796///membrane protein complex+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005314///high-affinity glutamate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015501///glutamate:sodium symporter activity+++GO:0046872///metal ion binding GO:0001504///neurotransmitter uptake+++GO:0006865///amino acid transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0098712///L-glutamate import across plasma membrane 20514 20514 'Slc1a5' mRNA 1392 1511 1375 27.91 29.85 29.26 16.48 16.14 15.85 29.00666667 16.15666667 945 903 881 1426 909.6666667 1.05E-15 -0.659955597 04974///Protein digestion and absorption+++05230///Central carbon metabolism in cancer GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042470///melanosome+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0046872///metal ion binding GO:0001504///neurotransmitter uptake+++GO:0006865///amino acid transport+++GO:0006868///glutamine transport+++GO:0010585///glutamine secretion+++GO:0015813///L-glutamate transmembrane transport+++GO:0015825///L-serine transport+++GO:0055085///transmembrane transport+++GO:0070207///protein homotrimerization+++GO:0098656///anion transmembrane transport+++GO:0098810///neurotransmitter reuptake+++GO:0140009///L-aspartate import across plasma membrane+++GO:1903803///L-glutamine import across plasma membrane 20515 20515 'Slc20a1' mRNA 280 320 311 5.97 6.68 6.9 9.88 9.63 9.61 6.516666667 9.706666667 537 526 535 303.6666667 532.6666667 5.47E-10 0.798106863 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0005316///high-affinity inorganic phosphate:sodium symporter activity+++GO:0015293///symporter activity GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0031214///biomineral tissue development+++GO:0035435///phosphate ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport 20516 20516 'Slc20a2' mRNA 1469.22 1656 1383 22.61 24.81 23.31 20.01 19.8 19.73 23.57666667 19.84666667 1456.26 1425 1386 1502.74 1422.42 0.345934984 -0.088802117 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0016032///viral process+++GO:0035435///phosphate ion transmembrane transport+++GO:0055085///transmembrane transport 20517 20517 'Slc22a1' mRNA 0 3 1 0 0.08 0.03 0.03 0.08 0 0.036666667 0.036666667 1.01 3.04 0 1.333333333 1.35 0.998591786 0.01073292 04976///Bile secretion+++05231///Choline metabolism in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098793///presynapse GO:0005277///acetylcholine transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0005330///dopamine:sodium symporter activity+++GO:0005334///norepinephrine:sodium symporter activity+++GO:0008504///monoamine transmembrane transporter activity+++GO:0008513///secondary active organic cation transmembrane transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015214///pyrimidine nucleoside transmembrane transporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0042910///xenobiotic transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006836///neurotransmitter transport+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0015695///organic cation transport+++GO:0015697///quaternary ammonium group transport+++GO:0015844///monoamine transport+++GO:0015872///dopamine transport+++GO:0015874///norepinephrine transport+++GO:0042908///xenobiotic transport+++GO:0048241///epinephrine transport+++GO:0051610///serotonin uptake+++GO:0051620///norepinephrine uptake+++GO:0055085///transmembrane transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:0090494///dopamine uptake+++GO:0098655///cation transmembrane transport+++GO:1901374///acetate ester transport+++GO:1901998///toxin transport+++GO:1990962///drug transport across blood-brain barrier 20518 20518 'Slc22a2' mRNA 179 188 185 4.73 4.89 5.22 10.51 10.24 10.89 4.946666667 10.54666667 455.99 432.96 458 184 448.9833333 3.15E-19 1.272532447 05231///Choline metabolism in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098793///presynapse GO:0005275///amine transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0005496///steroid binding+++GO:0008504///monoamine transmembrane transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015214///pyrimidine nucleoside transmembrane transporter activity+++GO:0015220///choline transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006836///neurotransmitter transport+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0015695///organic cation transport+++GO:0015697///quaternary ammonium group transport+++GO:0015837///amine transport+++GO:0015871///choline transport+++GO:0042908///xenobiotic transport+++GO:0051608///histamine transport+++GO:0051610///serotonin uptake+++GO:0051615///histamine uptake+++GO:0051620///norepinephrine uptake+++GO:0055085///transmembrane transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:0090494///dopamine uptake+++GO:0097638///L-arginine import across plasma membrane+++GO:0140115///export across plasma membrane+++GO:1901998///toxin transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1990962///drug transport across blood-brain barrier 20519 20519 'Slc22a3' mRNA 1759 1937 1733 27.32 29.6 28.55 2.59 2.46 2.82 28.49 2.623333333 192 178 202 1809.666667 190.6666667 7.26E-223 -3.257657478 05231///Choline metabolism in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0098793///presynapse GO:0005326///neurotransmitter transporter activity+++GO:0005330///dopamine:sodium symporter activity+++GO:0008504///monoamine transmembrane transporter activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006836///neurotransmitter transport+++GO:0006837///serotonin transport+++GO:0015695///organic cation transport+++GO:0015697///quaternary ammonium group transport+++GO:0015711///organic anion transport+++GO:0015718///monocarboxylic acid transport+++GO:0015844///monoamine transport+++GO:0015850///organic hydroxy compound transport+++GO:0015872///dopamine transport+++GO:0032098///regulation of appetite+++GO:0042908///xenobiotic transport+++GO:0051608///histamine transport+++GO:0051610///serotonin uptake+++GO:0051615///histamine uptake+++GO:0051620///norepinephrine uptake+++GO:0051625///epinephrine uptake+++GO:0055085///transmembrane transport+++GO:0090494///dopamine uptake+++GO:1901998///toxin transport 20520 20520 'Slc22a5' mRNA 812.44 797.89 758.08 14.39 13.86 14.43 14.02 14.84 15.44 14.22666667 14.76666667 892.24 943.25 969.24 789.47 934.91 0.020552642 0.233934723 05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015226///carnitine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding+++GO:1901235///(R)-carnitine transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007005///mitochondrion organization+++GO:0007512///adult heart development+++GO:0007626///locomotory behavior+++GO:0009437///carnitine metabolic process+++GO:0009609///response to symbiotic bacterium+++GO:0015697///quaternary ammonium group transport+++GO:0015879///carnitine transport+++GO:0048608///reproductive structure development+++GO:0055085///transmembrane transport+++GO:0060731///positive regulation of intestinal epithelial structure maintenance+++GO:0070715///sodium-dependent organic cation transport+++GO:1902270///(R)-carnitine transmembrane transport 20521 20521 'Slc22a12' mRNA 3 1 0 0.07 0.02 0 0.02 0.04 0.07 0.03 0.043333333 1 2 3 1.333333333 2 0.824676248 0.603002456 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005515///protein binding+++GO:0015143///urate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding GO:0006811///ion transport+++GO:0009410///response to xenobiotic stimulus+++GO:0015711///organic anion transport+++GO:0015747///urate transport+++GO:0042493///response to drug+++GO:0046415///urate metabolic process+++GO:0055085///transmembrane transport 20522 20522 'Slc23a1' mRNA 12.41 14.59 12 0.23 0.26 0.23 0.19 0.12 0.16 0.24 0.156666667 11.88 7.21 9.93 13 9.673333333 0.580448874 -0.506368936 04977///Vitamin digestion and absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043229///intracellular organelle GO:0005215///transporter activity+++GO:0008520///L-ascorbate:sodium symporter activity+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007420///brain development+++GO:0009636///response to toxic substance+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0030324///lung development+++GO:0055085///transmembrane transport+++GO:0070837///dehydroascorbic acid transport+++GO:0070904///transepithelial L-ascorbic acid transport 20523 20523 'Slc25a14' mRNA 612 682 620 25.16 27.62 27.02 13.16 13.11 14.12 26.6 13.46333333 367 365 381 638 371 8.07E-12 -0.793219959 GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0015116///sulfate transmembrane transporter activity+++GO:0015117///thiosulfate transmembrane transporter activity+++GO:0015131///oxaloacetate transmembrane transporter activity+++GO:0015140///malate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015297///antiporter activity GO:0006839///mitochondrial transport+++GO:0008272///sulfate transport+++GO:0015709///thiosulfate transport+++GO:0015729///oxaloacetate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0071423///malate transmembrane transport+++GO:1902356///oxaloacetate(2-) transmembrane transport+++GO:1902358///sulfate transmembrane transport 20524 20524 'Slc25a17' mRNA 1137 1129 1082 39.7 38.86 40.08 44.49 43.75 45.6 39.54666667 44.61333333 1464 1405 1452 1116 1440.333333 7.72E-06 0.356437806 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0015228///coenzyme A transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity+++GO:0044610///FMN transmembrane transporter activity+++GO:0051087///chaperone binding+++GO:0051724///NAD transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity GO:0006635///fatty acid beta-oxidation+++GO:0015866///ADP transport+++GO:0015867///ATP transport+++GO:0015908///fatty acid transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0035350///FAD transmembrane transport+++GO:0035352///NAD transmembrane transport+++GO:0043132///NAD transport+++GO:0055085///transmembrane transport+++GO:0080121///AMP transport 20525 20525 'Slc2a1' mRNA 7550 7723 7854 163.09 164.46 180.34 132.33 128.26 132.98 169.2966667 131.19 7042 6654 6852 7709 6849.333333 0.003438021 -0.18436802 04066///HIF-1 signaling pathway+++04911///Insulin secretion+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04976///Bile secretion+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05415///Diabetic cardiomyopathy GO:0001917///photoreceptor inner segment+++GO:0001939///female pronucleus+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005911///cell-cell junction+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0030496///midbody+++GO:0030864///cortical actin cytoskeleton+++GO:0031982///vesicle+++GO:0042383///sarcolemma+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005324///long-chain fatty acid transporter activity+++GO:0005355///glucose transmembrane transporter activity+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0043621///protein self-association+++GO:0055056///D-glucose transmembrane transporter activity GO:0001666///response to hypoxia+++GO:0006970///response to osmotic stress+++GO:0007417///central nervous system development+++GO:0007565///female pregnancy+++GO:0008643///carbohydrate transport+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0021987///cerebral cortex development+++GO:0032868///response to insulin+++GO:0042149///cellular response to glucose starvation+++GO:0042908///xenobiotic transport+++GO:0045494///photoreceptor cell maintenance+++GO:0055085///transmembrane transport+++GO:0065003///protein-containing complex assembly+++GO:0070837///dehydroascorbic acid transport+++GO:0071260///cellular response to mechanical stimulus+++GO:0071474///cellular hyperosmotic response+++GO:0098708///glucose import across plasma membrane+++GO:1904016///response to Thyroglobulin triiodothyronine+++GO:1904659///glucose transmembrane transport 20526 20526 'Slc2a2' mRNA 5 3 6 0.11 0.06 0.14 0 0.04 0.08 0.103333333 0.04 0 2 4 4.666666667 2 0.468741095 -1.236372529 04911///Insulin secretion+++04917///Prolactin signaling pathway+++04922///Glucagon signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04950///Maturity onset diabetes of the young+++04973///Carbohydrate digestion and absorption+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005158///insulin receptor binding+++GO:0005353///fructose transmembrane transporter activity+++GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0009758///carbohydrate utilization+++GO:0015755///fructose transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070837///dehydroascorbic acid transport+++GO:1904659///glucose transmembrane transport 20527 20527 'Slc2a3' mRNA 92 88 115 1.24 1.16 1.66 2.33 1.98 1.98 1.353333333 2.096666667 201 164 163 98.33333333 176 4.14E-04 0.820633657 GO:0002080///acrosomal membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0098978///glutamatergic synapse+++GO:0099699///integral component of synaptic membrane GO:0005355///glucose transmembrane transporter activity+++GO:0005536///glucose binding+++GO:0015145///monosaccharide transmembrane transporter activity+++GO:0016936///galactoside binding+++GO:0019900///kinase binding+++GO:0022857///transmembrane transporter activity+++GO:0033222///xylose binding+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport+++GO:0070837///dehydroascorbic acid transport+++GO:0098708///glucose import across plasma membrane+++GO:1904659///glucose transmembrane transport 20528 20528 'Slc2a4' mRNA 282 263 299 5.9 5.21 6.54 3.99 3.48 5.01 5.883333333 4.16 216 194 269 281.3333333 226.3333333 0.089943939 -0.328742728 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030136///clathrin-coated vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030315///T-tubule+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031982///vesicle+++GO:0032593///insulin-responsive compartment+++GO:0042383///sarcolemma+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0098793///presynapse GO:0005355///glucose transmembrane transporter activity+++GO:0005360///insulin-responsive glucose:proton symporter activity+++GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0007611///learning or memory+++GO:0007614///short-term memory+++GO:0007616///long-term memory+++GO:0008643///carbohydrate transport+++GO:0010021///amylopectin biosynthetic process+++GO:0031550///positive regulation of brain-derived neurotrophic factor receptor signaling pathway+++GO:0032869///cellular response to insulin stimulus+++GO:0042593///glucose homeostasis+++GO:0044381///glucose import in response to insulin stimulus+++GO:0045471///response to ethanol+++GO:0046323///glucose import+++GO:0050873///brown fat cell differentiation+++GO:0055085///transmembrane transport+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071456///cellular response to hypoxia+++GO:0071470///cellular response to osmotic stress+++GO:0098694///regulation of synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:1904659///glucose transmembrane transport 20529 20529 'Slc31a1' mRNA 1693 1771 1813 24.5 25.21 27.83 40.85 41.97 38.36 25.84666667 40.39333333 3249 3261 2955 1759 3155 2.47E-27 0.829347402 01524///Platinum drug resistance+++04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome GO:0005375///copper ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0015677///copper ion import+++GO:0035434///copper ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0072719///cellular response to cisplatin+++GO:0098705///copper ion import across plasma membrane 20530 20530 'Slc31a2' mRNA 1038 1126 1008 32.41 34.64 33.39 100.58 93.71 94.49 33.48 96.26 3703 3366 3365 1057.333333 3478 3.49E-136 1.706333362 GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0005375///copper ion transmembrane transporter activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0035434///copper ion transmembrane transport+++GO:1902311///regulation of copper ion transmembrane transport 20531 20531 'Slc34a2' mRNA 937 918 1006 12.09 11.65 13.77 4 4.38 4.77 12.50333333 4.383333333 357 382 412 953.6666667 383.6666667 1.95E-30 -1.327476441 "04928///Parathyroid hormone synthesis, secretion and action+++04978///Mineral absorption" GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0031982///vesicle GO:0005436///sodium:phosphate symporter activity+++GO:0015293///symporter activity+++GO:0019904///protein domain specific binding+++GO:0031402///sodium ion binding+++GO:0042301///phosphate ion binding GO:0001701///in utero embryonic development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0035725///sodium ion transmembrane transport+++GO:0043627///response to estrogen+++GO:0044341///sodium-dependent phosphate transport+++GO:0055085///transmembrane transport 20532 20532 'Slc3a1' mRNA 12.72 8.99 3.74 0.31 0.22 0.1 0.03 0 0.03 0.21 0.02 1.27 0 1.22 8.483333333 0.83 0.032260186 -3.520981992 04974///Protein digestion and absorption GO:0005743///mitochondrial inner membrane+++GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity GO:0005975///carbohydrate metabolic process+++GO:0006865///amino acid transport+++GO:0010467///gene expression+++GO:0015810///aspartate transmembrane transport+++GO:0015811///L-cystine transport+++GO:0015813///L-glutamate transmembrane transport 20533 20533 'Slc4a1' mRNA 5 3 0 0.06 0.03 0 0.03 0 0.06 0.03 0.03 3 0 6 2.666666667 3 0.935175452 0.182761371 04966///Collecting duct acid secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030018///Z disc+++GO:0030863///cortical cytoskeleton GO:0003779///actin binding+++GO:0005452///inorganic anion exchanger activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019899///enzyme binding+++GO:0022857///transmembrane transporter activity+++GO:0030492///hemoglobin binding+++GO:0030506///ankyrin binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0007596///blood coagulation+++GO:0010037///response to carbon dioxide+++GO:0014823///response to activity+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0017121///phospholipid scrambling+++GO:0035811///negative regulation of urine volume+++GO:0042102///positive regulation of T cell proliferation+++GO:0042542///response to hydrogen peroxide+++GO:0045852///pH elevation+++GO:0046685///response to arsenic-containing substance+++GO:0048821///erythrocyte development+++GO:0050801///ion homeostasis+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0098656///anion transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:1904539///negative regulation of glycolytic process through fructose-6-phosphate 20534 20534 'Slc4a1ap' mRNA 833.22 750.23 722.71 14.14 12.45 12.69 11.54 12.55 11.58 13.09333333 11.89 713.41 698.69 703.91 768.72 705.3366667 0.237264952 -0.135624202 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0008150///biological_process 20535 20535 'Slc4a2' mRNA 1398 1454 1310 18.5 18.74 18.17 15.63 16.05 15.62 18.47 15.76666667 1363 1376 1316 1387.333333 1351.666667 0.637402758 -0.047935744 04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019899///enzyme binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0007283///spermatogenesis+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0048565///digestive tract development+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0070175///positive regulation of enamel mineralization+++GO:0097186///amelogenesis+++GO:0098656///anion transmembrane transport+++GO:1902476///chloride transmembrane transport 20536 20536 'Slc4a3' mRNA 737 738 578 8.72 8.82 7.48 5.3 5.85 5.67 8.34 5.606666667 510 549 525 684.3333333 528 0.001427525 -0.380674781 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019899///enzyme binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0061337///cardiac conduction+++GO:0098656///anion transmembrane transport 20537 20537 'Slc5a1' mRNA 48 54 42 0.66 0.73 0.61 1.15 0.79 1.06 0.666666667 1 96 65 86 48 82.33333333 0.019282871 0.767301148 04973///Carbohydrate digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0043229///intracellular organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005355///glucose transmembrane transporter activity+++GO:0005372///water transmembrane transporter activity+++GO:0005412///glucose:sodium symporter activity+++GO:0015151///alpha-glucoside transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0000017///alpha-glucoside transport+++GO:0001656///metanephros development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008643///carbohydrate transport+++GO:0010035///response to inorganic substance+++GO:0032409///regulation of transporter activity+++GO:0035377///transepithelial water transport+++GO:0050892///intestinal absorption+++GO:0055085///transmembrane transport+++GO:0098708///glucose import across plasma membrane+++GO:0098719///sodium ion import across plasma membrane+++GO:1904659///glucose transmembrane transport 20538 20538 'Slc6a2' mRNA 2 2.12 1.99 0.02 0.02 0.02 0 0 0 0.02 0 0 0 0 2.036666667 0 0.330935189 -3.178038812 04721///Synaptic vesicle cycle GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031045///dense core granule+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0098690///glycinergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0003779///actin binding+++GO:0005326///neurotransmitter transporter activity+++GO:0005328///neurotransmitter:sodium symporter activity+++GO:0005330///dopamine:sodium symporter activity+++GO:0005334///norepinephrine:sodium symporter activity+++GO:0008504///monoamine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015375///glycine:sodium symporter activity+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding "GO:0001504///neurotransmitter uptake+++GO:0006836///neurotransmitter transport+++GO:0015816///glycine transport+++GO:0015844///monoamine transport+++GO:0015874///norepinephrine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042493///response to drug+++GO:0048265///response to pain+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0051620///norepinephrine uptake+++GO:0055085///transmembrane transport+++GO:0060012///synaptic transmission, glycinergic+++GO:0098810///neurotransmitter reuptake+++GO:1903804///glycine import across plasma membrane" 20539 20539 'Slc7a5' mRNA 1036 987 520 16.03 15.03 8.54 7.37 8.7 7.87 13.2 7.98 548 632 567 847.6666667 582.3333333 0.092843487 -0.537574371 04150///mTOR signaling pathway+++05230///Central carbon metabolism in cancer GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098591///external side of apical plasma membrane+++GO:1990184///amino acid transport complex GO:0015171///amino acid transmembrane transporter activity+++GO:0015173///aromatic amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015190///L-leucine transmembrane transporter activity+++GO:0015196///L-tryptophan transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0010629///negative regulation of gene expression+++GO:0015807///L-amino acid transport+++GO:0015823///phenylalanine transport+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:0089718///amino acid import across plasma membrane+++GO:0098713///leucine import across plasma membrane+++GO:1903801///L-leucine import across plasma membrane+++GO:1904556///L-tryptophan transmembrane transport 20540 20540 'Slc7a7' mRNA 96.31 126 109.35 2.48 3.3 3.17 18.48 17.78 18.62 2.983333333 18.29333333 733.78 673.99 738.86 110.5533333 715.5433333 2.22E-78 2.683930637 04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0000821///regulation of arginine metabolic process+++GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015807///L-amino acid transport+++GO:0055085///transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1990822///basic amino acid transmembrane transport 20541 20541 'Slc8a1' mRNA 148 134 130 0.78 0.44 0.54 1.57 1.24 1.3 0.586666667 1.37 225 178 188 137.3333333 197 0.013123673 0.507628697 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04740///Olfactory transduction+++04961///Endocrine and other factor-regulated calcium reabsorption+++04974///Protein digestion and absorption+++04978///Mineral absorption+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0071944///cell periphery+++GO:0098794///postsynapse+++GO:0099055///integral component of postsynaptic membrane GO:0005432///calcium:sodium antiporter activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008092///cytoskeletal protein binding+++GO:0015297///antiporter activity+++GO:0015491///cation:cation antiporter activity+++GO:0030506///ankyrin binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0086038///calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential+++GO:0099580///ion antiporter activity involved in regulation of postsynaptic membrane potential+++GO:1905060///calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration GO:0001666///response to hypoxia+++GO:0001892///embryonic placenta development+++GO:0002026///regulation of the force of heart contraction+++GO:0002027///regulation of heart rate+++GO:0002028///regulation of sodium ion transport+++GO:0003007///heart morphogenesis+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006883///cellular sodium ion homeostasis+++GO:0007154///cell communication+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007584///response to nutrient+++GO:0008217///regulation of blood pressure+++GO:0009749///response to glucose+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0010763///positive regulation of fibroblast migration+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0014829///vascular smooth muscle contraction+++GO:0021537///telencephalon development+++GO:0030001///metal ion transport+++GO:0030501///positive regulation of bone mineralization+++GO:0033198///response to ATP+++GO:0034614///cellular response to reactive oxygen species+++GO:0035050///embryonic heart tube development+++GO:0035725///sodium ion transmembrane transport+++GO:0035902///response to immobilization stress+++GO:0035994///response to muscle stretch+++GO:0036376///sodium ion export across plasma membrane+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0044557///relaxation of smooth muscle+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051924///regulation of calcium ion transport+++GO:0055001///muscle cell development+++GO:0055013///cardiac muscle cell development+++GO:0055074///calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060048///cardiac muscle contraction+++GO:0060402///calcium ion transport into cytosol+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0071313///cellular response to caffeine+++GO:0071320///cellular response to cAMP+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0098703///calcium ion import across plasma membrane+++GO:0098719///sodium ion import across plasma membrane+++GO:0098735///positive regulation of the force of heart contraction+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:1901660///calcium ion export+++GO:1903416///response to glycoside 20544 20544 'Slc9a1' mRNA 1020 1030 1118 13.24 12.77 15.12 12.17 12.05 12.86 13.71 12.36 1096 1038 1102 1056 1078.666667 0.900095552 0.015849838 04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04810///Regulation of actin cytoskeleton+++04919///Thyroid hormone signaling pathway+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05205///Proteoglycans in cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030315///T-tubule+++GO:0042383///sarcolemma+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0090533///cation-transporting ATPase complex GO:0005516///calmodulin binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity+++GO:0030346///protein phosphatase 2B binding+++GO:0048306///calcium-dependent protein binding GO:0002026///regulation of the force of heart contraction+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0006885///regulation of pH+++GO:0009790///embryo development+++GO:0010447///response to acidic pH+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0014070///response to organic cyclic compound+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0032869///cellular response to insulin stimulus+++GO:0035725///sodium ion transmembrane transport+++GO:0035794///positive regulation of mitochondrial membrane permeability+++GO:0035994///response to muscle stretch+++GO:0036376///sodium ion export across plasma membrane+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045760///positive regulation of action potential+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051259///protein complex oligomerization+++GO:0051453///regulation of intracellular pH+++GO:0051930///regulation of sensory perception of pain+++GO:0055007///cardiac muscle cell differentiation+++GO:0055085///transmembrane transport+++GO:0070417///cellular response to cold+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0070997///neuron death+++GO:0071236///cellular response to antibiotic+++GO:0071257///cellular response to electrical stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0071468///cellular response to acidic pH+++GO:0071805///potassium ion transmembrane transport+++GO:0071872///cellular response to epinephrine stimulus+++GO:0086003///cardiac muscle cell contraction+++GO:0086092///regulation of the force of heart contraction by cardiac conduction+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:0098735///positive regulation of the force of heart contraction+++GO:1902533///positive regulation of intracellular signal transduction+++GO:1902600///proton transmembrane transport+++GO:1903281///positive regulation of calcium:sodium antiporter activity 20555 20555 'Slfn1' mRNA 39 21 44 1.18 0.63 1.41 19.09 19.61 17.9 1.073333333 18.86666667 725 727 658 34.66666667 703.3333333 4.81E-105 4.327310432 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0051726///regulation of cell cycle+++GO:1900477///negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 20556 20556 'Slfn2' mRNA 224 244 265 7.84 8.42 9.84 75.91 85.89 80.12 8.7 80.64 2492.85 2752.99 2546 244.3333333 2597.28 3.32E-246 3.397210791 GO:0008285///negative regulation of cell proliferation+++GO:0009617///response to bacterium 20557 20557 'Slfn3' mRNA 9 3 9 0.29 0.09 0.3 0.97 0.45 0.86 0.226666667 0.76 35.34 16.01 30.1 7 27.15 0.005784959 1.921291829 GO:0008285///negative regulation of cell proliferation 20558 20558 'Slfn4' mRNA 70 77 91 0.96 1.04 1.38 21.99 19.3 19.79 1.126666667 20.36 1793.81 1541 1548.9 79.33333333 1627.903333 3.64E-229 4.343794591 GO:0005575///cellular_component GO:0003674///molecular_function GO:0009617///response to bacterium 20562 20562 'Slit1' mRNA 4 2 3 0.03 0.02 0.02 0.13 0 0.16 0.023333333 0.096666667 16 0 21 3 12.33333333 0.108837441 2.016493542 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048495///Roundabout binding GO:0007097///nuclear migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0021772///olfactory bulb development+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0022029///telencephalon cell migration+++GO:0030154///cell differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0033563///dorsal/ventral axon guidance+++GO:0048812///neuron projection morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0051964///negative regulation of synapse assembly 20563 20563 'Slit2' mRNA 491 575 408 2.57 2.95 2.27 2.47 2.13 2.25 2.596666667 2.283333333 541 455 479 491.3333333 491.6666667 0.974713239 -0.006711514 04360///Axon guidance+++04361///Axon regeneration GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0062023///collagen-containing extracellular matrix GO:0005095///GTPase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043237///laminin-1 binding+++GO:0043394///proteoglycan binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0045499///chemorepellent activity+++GO:0048495///Roundabout binding GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002689///negative regulation of leukocyte chemotaxis+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0006935///chemotaxis+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0008285///negative regulation of cell proliferation+++GO:0010593///negative regulation of lamellipodium assembly+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0021772///olfactory bulb development+++GO:0021836///chemorepulsion involved in postnatal olfactory bulb interneuron migration+++GO:0021972///corticospinal neuron axon guidance through spinal cord+++GO:0022029///telencephalon cell migration+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0030837///negative regulation of actin filament polymerization+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032870///cellular response to hormone stimulus+++GO:0033563///dorsal/ventral axon guidance+++GO:0035385///Roundabout signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043116///negative regulation of vascular permeability+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048812///neuron projection morphogenesis+++GO:0048846///axon extension involved in axon guidance+++GO:0050728///negative regulation of inflammatory response+++GO:0050919///negative chemotaxis+++GO:0050929///induction of negative chemotaxis+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0051414///response to cortisol+++GO:0060412///ventricular septum morphogenesis+++GO:0060603///mammary gland duct morphogenesis+++GO:0060763///mammary duct terminal end bud growth+++GO:0061364///apoptotic process involved in luteolysis+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:0071504///cellular response to heparin+++GO:0071672///negative regulation of smooth muscle cell chemotaxis+++GO:0071676///negative regulation of mononuclear cell migration+++GO:0090024///negative regulation of neutrophil chemotaxis+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0090288///negative regulation of cellular response to growth factor stimulus+++GO:0098609///cell-cell adhesion 20564 20564 'Slit3' mRNA 498 550 309 5.33 5.78 3.51 1.11 1.14 1.34 4.873333333 1.196666667 119 120 140 452.3333333 126.3333333 1.31E-21 -1.840252035 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048495///Roundabout binding GO:0003180///aortic valve morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0007097///nuclear migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010629///negative regulation of gene expression+++GO:0021772///olfactory bulb development+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0022029///telencephalon cell migration+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032870///cellular response to hormone stimulus+++GO:0033563///dorsal/ventral axon guidance+++GO:0035385///Roundabout signaling pathway+++GO:0048812///neuron projection morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0051414///response to cortisol+++GO:0051964///negative regulation of synapse assembly+++GO:0060412///ventricular septum morphogenesis+++GO:0061364///apoptotic process involved in luteolysis+++GO:0070100///negative regulation of chemokine-mediated signaling pathway 20568 20568 'Slpi' mRNA 138 124 150 10.36 9.28 12.04 120.34 126.92 119.47 10.56 122.2433333 1823 1874 1750 137.3333333 1815.666667 7.13E-233 3.71176468 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus GO:0003677///DNA binding+++GO:0003729///mRNA binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0019899///enzyme binding+++GO:0030414///peptidase inhibitor activity GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006955///immune response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0032091///negative regulation of protein binding+++GO:0032496///response to lipopolysaccharide+++GO:0035821///modification of morphology or physiology of other organism+++GO:0042742///defense response to bacterium+++GO:0043086///negative regulation of catalytic activity+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 20583 20583 'Snai2' mRNA 45 47 34 1.26 1.3 1.01 1.44 0.95 0.96 1.19 1.116666667 59 38 38 42 45 0.863090843 0.089194657 04390///Hippo signaling pathway+++04520///Adherens junction GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001837///epithelial to mesenchymal transition+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003273///cell migration involved in endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006929///substrate-dependent cell migration+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0009314///response to radiation+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0010957///negative regulation of vitamin D biosynthetic process+++GO:0014032///neural crest cell development+++GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032642///regulation of chemokine production+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0035066///positive regulation of histone acetylation+++GO:0035921///desmosome disassembly+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0044319///wound healing, spreading of cells+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0050872///white fat cell differentiation+++GO:0060021///roof of mouth development+++GO:0060429///epithelium development+++GO:0060536///cartilage morphogenesis+++GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0070563///negative regulation of vitamin D receptor signaling pathway+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071479///cellular response to ionizing radiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000647///negative regulation of stem cell proliferation+++GO:2000810///regulation of bicellular tight junction assembly+++GO:2000811///negative regulation of anoikis+++GO:2001028///positive regulation of endothelial cell chemotaxis+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 20585 20585 'Hltf' mRNA 656.21 633.85 649.85 7.19 6.94 7.57 8.08 7.27 7 7.233333333 7.45 863.3 773.75 737.93 646.6366667 791.66 0.011844849 0.278438356 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070615///nucleosome-dependent ATPase activity" GO:0006325///chromatin organization+++GO:0008152///metabolic process+++GO:0016567///protein ubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II 20586 20586 'Smarca4' mRNA 2189 2217 2026 20.89 20.87 20.59 25.84 23.15 24.66 20.78333333 24.55 3077 2699 2858 2144 2878 4.81E-10 0.41312102 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0000166///nucleotide binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0030957///Tat protein binding+++GO:0042393///histone binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0050681///androgen receptor binding+++GO:0070182///DNA polymerase binding+++GO:0070577///lysine-acetylated histone binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001832///blastocyst growth+++GO:0001835///blastocyst hatching+++GO:0001889///liver development+++GO:0003151///outflow tract morphogenesis+++GO:0003281///ventricular septum development+++GO:0003407///neural retina development+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006346///methylation-dependent chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0007403///glial cell fate determination+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0010424///DNA methylation on cytosine within a CG sequence+++GO:0010467///gene expression+++GO:0019827///stem cell population maintenance+++GO:0022008///neurogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030198///extracellular matrix organization+++GO:0030216///keratinocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0030900///forebrain development+++GO:0030902///hindbrain development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035887///aortic smooth muscle cell differentiation+++GO:0035904///aorta development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043066///negative regulation of apoptotic process+++GO:0043388///positive regulation of DNA binding+++GO:0043923///positive regulation by host of viral transcription+++GO:0043966///histone H3 acetylation+++GO:0045597///positive regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048562///embryonic organ morphogenesis+++GO:0048730///epidermis morphogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060318///definitive erythrocyte differentiation+++GO:0060347///heart trabecula formation+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0060976///coronary vasculature development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0070307///lens fiber cell development+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902661///positive regulation of glucose mediated signaling pathway+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 20587 20587 'Smarcb1' mRNA 1955 1854 1971 69.13 64.63 73.95 73.83 73.25 70.47 69.23666667 72.51666667 2391 2315 2208 1926.666667 2304.666667 0.002250648 0.244593449 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0001650///fibrillar center+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016514///SWI/SNF complex+++GO:0035060///brahma complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0030957///Tat protein binding GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0001824///blastocyst development+++GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0039692///single stranded viral RNA replication via double stranded DNA intermediate+++GO:0043923///positive regulation by host of viral transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0090240///positive regulation of histone H4 acetylation+++GO:1900110///negative regulation of histone H3-K9 dimethylation+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902661///positive regulation of glucose mediated signaling pathway+++GO:2000617///positive regulation of histone H3-K9 acetylation 20588 20588 'Smarcc1' mRNA 806 871 400 7.55 8.03 3.98 4.42 4.3 4.95 6.52 4.556666667 543 516 589 692.3333333 549.3333333 0.38658287 -0.32928825 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0001741///XY body+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0047485///protein N-terminus binding "GO:0006323///DNA packaging+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0007399///nervous system development+++GO:0008286///insulin receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0030850///prostate gland development+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 20589 20589 'Ighmbp2' mRNA 304 326 252 4.76 4.57 3.96 3.5 3.03 3.12 4.43 3.216666667 274 232 236 294 247.3333333 0.138006353 -0.258295244 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008134///transcription factor binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0032574///5'-3' RNA helicase activity+++GO:0042802///identical protein binding+++GO:0043022///ribosome binding+++GO:0043139///5'-3' DNA helicase activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:1990955///G-rich single-stranded DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0021522///spinal cord motor neuron differentiation+++GO:0032508///DNA duplex unwinding+++GO:0050905///neuromuscular process 20591 20591 'Kdm5c' mRNA 1681 1705 1361 10.02 10.38 8.26 9.79 8.7 8.6 9.553333333 9.03 1728 1529 1501 1582.333333 1586 0.966682746 -0.005362278 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0009636///response to toxic substance+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0042752///regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 20592 20592 'Kdm5d' mRNA 239 259 222 2.64 3.17 2.83 2.65 2.33 2.47 2.88 2.483333333 269 237 241 240 249 0.861161129 0.042336376 GO:0001650///fibrillar center+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051213///dioxygenase activity "GO:0002457///T cell antigen processing and presentation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0060765///regulation of androgen receptor signaling pathway" 20595 20595 'Smn1' mRNA 580.75 543.02 501.47 27.56 25.42 25.12 24.75 23.2 24.45 26.03333333 24.13333333 594.73 539.02 564 541.7466667 565.9166667 0.731744501 0.052557657 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0030018///Z disc+++GO:0030137///COPI-coated vesicle+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0097504///Gemini of coiled bodies GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0017134///fibroblast growth factor binding+++GO:0042802///identical protein binding "GO:0000387///spliceosomal snRNP assembly+++GO:0006353///DNA-templated transcription, termination+++GO:0006397///mRNA processing+++GO:0007019///microtubule depolymerization+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0008380///RNA splicing+++GO:0010975///regulation of neuron projection development+++GO:0033120///positive regulation of RNA splicing" 20597 20597 'Smpd1' mRNA 3403 3537 3402 78.85 80.7 83.62 61.31 63.32 59.91 81.05666667 61.51333333 3043 3069 2879 3447.333333 2997 0.00146199 -0.213904185 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++04142///Lysosome+++04217///Necroptosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036019///endolysosome+++GO:0042599///lamellar body "GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding+++GO:0061750///acid sphingomyelin phosphodiesterase activity" GO:0001778///plasma membrane repair+++GO:0006672///ceramide metabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0008152///metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009615///response to virus+++GO:0010212///response to ionizing radiation+++GO:0023021///termination of signal transduction+++GO:0034340///response to type I interferon+++GO:0034612///response to tumor necrosis factor+++GO:0034644///cellular response to UV+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0042060///wound healing+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045807///positive regulation of endocytosis+++GO:0046513///ceramide biosynthetic process+++GO:0046718///viral entry into host cell+++GO:0070555///response to interleukin-1+++GO:0071277///cellular response to calcium ion 20598 20598 'Smpd2' mRNA 1330 1398 1283 45.52 46.76 46.71 35.91 36.43 36.47 46.33 36.27 1181 1158 1166 1337 1168.333333 0.013791218 -0.205564475 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery GO:0003824///catalytic activity+++GO:0004620///phospholipase activity+++GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006684///sphingomyelin metabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0009612///response to mechanical stimulus+++GO:0030149///sphingolipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0046513///ceramide biosynthetic process 20599 20599 'Smr3a' mRNA 0 3 0 0 0.34 0 0.1 0 0 0.113333333 0.033333333 1 0 0 1 0.333333333 0.754495413 -1.44848948 GO:0005576///extracellular region GO:0004866///endopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0051930///regulation of sensory perception of pain 20602 20602 'Ncor2' mRNA 2438.94 2431.57 1477.56 13.92 13.64 8.86 10.86 10.5 10.9 12.14 10.75333333 2202.08 2041.83 2127.73 2116.023333 2123.88 0.994874091 0.004234354 04330///Notch signaling pathway+++05169///Epstein-Barr virus infection GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0035257///nuclear hormone receptor binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042826///histone deacetylase binding+++GO:0042974///retinoic acid receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046965///retinoid X receptor binding+++GO:0047485///protein N-terminus binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0003007///heart morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007595///lactation+++GO:0010243///response to organonitrogen compound+++GO:0010565///regulation of cellular ketone metabolic process+++GO:0021537///telencephalon development+++GO:0021846///cell proliferation in forebrain+++GO:0030900///forebrain development+++GO:0032355///response to estradiol+++GO:0042593///glucose homeostasis+++GO:0044849///estrous cycle+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050872///white fat cell differentiation+++GO:0060509///type I pneumocyte differentiation+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0090312///positive regulation of protein deacetylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA" 20603 20603 'Sms' mRNA 796 789 840 11.59 11.3 12.98 11.48 11.8 11.51 11.95666667 11.59666667 907 911 881 808.3333333 899.6666667 0.212059995 0.140763717 00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism+++00480///Glutathione metabolism GO:0016740///transferase activity+++GO:0016768///spermine synthase activity GO:0006596///polyamine biosynthetic process+++GO:0006597///spermine biosynthetic process+++GO:0008215///spermine metabolic process 20605 20605 'Sstr1' mRNA 7 1 5 0.1 0.01 0.07 0.06 0.04 0.09 0.06 0.063333333 5 3 7 4.333333333 5 0.902848273 0.18398045 "04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0004994///somatostatin receptor activity+++GO:0005515///protein binding+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007283///spermatogenesis+++GO:0021549///cerebellum development+++GO:0030900///forebrain development+++GO:0038170///somatostatin signaling pathway+++GO:0042594///response to starvation+++GO:0071392///cellular response to estradiol stimulus+++GO:1990830///cellular response to leukemia inhibitory factor 20606 20606 'Sstr2' mRNA 6 8 5 0.16 0.21 0.14 0.55 0.28 0.45 0.17 0.426666667 22 12 19 6.333333333 17.66666667 0.059395962 1.469541349 "04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action+++04971///Gastric acid secretion" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0004994///somatostatin receptor activity+++GO:0030165///PDZ domain binding+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0006937///regulation of muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007283///spermatogenesis+++GO:0021549///cerebellum development+++GO:0030432///peristalsis+++GO:0030900///forebrain development+++GO:0038170///somatostatin signaling pathway+++GO:0042594///response to starvation+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071392///cellular response to estradiol stimulus 20607 20607 'Sstr3' mRNA 10 9 6 0.14 0.11 0.09 0.05 0.09 0.04 0.113333333 0.06 4 8 3 8.333333333 5 0.530591093 -0.736179254 "04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0004930///G protein-coupled receptor activity+++GO:0004994///somatostatin receptor activity+++GO:0005102///signaling receptor binding+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007283///spermatogenesis+++GO:0021549///cerebellum development+++GO:0030900///forebrain development+++GO:0038170///somatostatin signaling pathway+++GO:0042594///response to starvation+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071392///cellular response to estradiol stimulus 20608 20608 'Sstr4' mRNA 4 1 1 0.17 0.04 0.05 0.23 0.12 0.31 0.086666667 0.22 6 3 8 2 5.666666667 0.322034445 1.496490581 04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0004994///somatostatin receptor activity+++GO:0005515///protein binding+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0016477///cell migration+++GO:0030900///forebrain development+++GO:0038170///somatostatin signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 20610 20610 'Sumo3' mRNA 3914 4077 3923 82.42 84.51 87.66 98.82 97.16 101.73 84.86333333 99.23666667 5397 5186 5387 3971.333333 5323.333333 1.25E-12 0.41048289 03013///Nucleocytoplasmic transport+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0106068///SUMO ligase complex GO:0019789///SUMO transferase activity+++GO:0031386///protein tag+++GO:0044389///ubiquitin-like protein ligase binding GO:0016925///protein sumoylation+++GO:0034504///protein localization to nucleus+++GO:0043392///negative regulation of DNA binding+++GO:1900180///regulation of protein localization to nucleus+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 20612 20612 'Siglec1' mRNA 245 247 232 2.04 2.03 2.07 34.02 31.3 36.22 2.046666667 33.84666667 4659 4182 4799 241.3333333 4546.666667 0 4.224202713 04514///Cell adhesion molecules GO:0005576///extracellular region+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0046790///virion binding GO:0006897///endocytosis+++GO:0007155///cell adhesion+++GO:0070234///positive regulation of T cell apoptotic process+++GO:0075512///clathrin-dependent endocytosis of virus by host cell+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 20613 20613 'Snai1' mRNA 44 57 54 1.59 2.03 2.06 8.09 8.1 7.68 1.893333333 7.956666667 258 252 237 51.66666667 249 3.18E-25 2.256370211 04520///Adherens junction GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0001707///mesoderm formation+++GO:0001837///epithelial to mesenchymal transition+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007498///mesoderm development+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010957///negative regulation of vitamin D biosynthetic process+++GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0031069///hair follicle morphogenesis+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060021///roof of mouth development+++GO:0060536///cartilage morphogenesis+++GO:0060707///trophoblast giant cell differentiation+++GO:0060806///negative regulation of cell differentiation involved in embryonic placenta development+++GO:0060972///left/right pattern formation+++GO:0061314///Notch signaling involved in heart development+++GO:0070828///heterochromatin organization+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000810///regulation of bicellular tight junction assembly" 20614 20614 'Snap25' mRNA 886 888 870 23.54 23.32 24.52 2.81 2.46 2.94 23.79333333 2.736666667 121 104 123 881.3333333 116 1.08E-110 -2.938305501 04721///Synaptic vesicle cycle+++04911///Insulin secretion GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0008076///voltage-gated potassium channel complex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031083///BLOC-1 complex+++GO:0031201///SNARE complex+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031982///vesicle+++GO:0036477///somatodendritic compartment+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043229///intracellular organelle+++GO:0044295///axonal growth cone+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0070032///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex+++GO:0070033///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099026///anchored component of presynaptic membrane GO:0000149///SNARE binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0017075///syntaxin-1 binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0044325///ion channel binding+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0007269///neurotransmitter secretion+++GO:0007616///long-term memory+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0010975///regulation of neuron projection development+++GO:0016079///synaptic vesicle exocytosis+++GO:0016082///synaptic vesicle priming+++GO:0016197///endosomal transport+++GO:0030431///sleep+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0031915///positive regulation of synaptic plasticity+++GO:0035493///SNARE complex assembly+++GO:0046887///positive regulation of hormone secretion+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0060291///long-term synaptic potentiation+++GO:0070201///regulation of establishment of protein localization+++GO:0071805///potassium ion transmembrane transport+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099590///neurotransmitter receptor internalization+++GO:1990926///short-term synaptic potentiation 20615 20615 'Snapin' mRNA 2739.95 2750.33 2747.88 81.81 80.92 87.04 67.43 61.34 63.77 83.25666667 64.18 2596.1 2305.33 2376.09 2746.053333 2425.84 0.008744191 -0.192228727 GO:0000139///Golgi membrane+++GO:0001669///acrosomal vesicle+++GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030672///synaptic vesicle membrane+++GO:0031083///BLOC-1 complex+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0099078///BORC complex+++GO:1904115///axon cytoplasm GO:0000149///SNARE binding+++GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0007040///lysosome organization+++GO:0007042///lysosomal lumen acidification+++GO:0007268///chemical synaptic transmission+++GO:0008089///anterograde axonal transport+++GO:0008090///retrograde axonal transport+++GO:0008333///endosome to lysosome transport+++GO:0010977///negative regulation of neuron projection development+++GO:0016079///synaptic vesicle exocytosis+++GO:0016188///synaptic vesicle maturation+++GO:0017156///calcium ion regulated exocytosis+++GO:0031175///neuron projection development+++GO:0031503///protein-containing complex localization+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0032418///lysosome localization+++GO:0034629///cellular protein-containing complex localization+++GO:0043393///regulation of protein binding+++GO:0048489///synaptic vesicle transport+++GO:0048490///anterograde synaptic vesicle transport+++GO:0051604///protein maturation+++GO:0072553///terminal button organization+++GO:0097352///autophagosome maturation+++GO:1902774///late endosome to lysosome transport+++GO:2000300///regulation of synaptic vesicle exocytosis 20616 20616 'Snap91' mRNA 892 962 812 11.88 12.89 11.62 2.28 1.83 2.26 12.13 2.123333333 181 142 185 888.6666667 169.3333333 7.06E-80 -2.402171811 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0031313///extrinsic component of endosome membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045211///postsynaptic membrane+++GO:0048787///presynaptic active zone membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098830///presynaptic endosome+++GO:0098833///presynaptic endocytic zone+++GO:0098894///extrinsic component of presynaptic endocytic zone membrane "GO:0000149///SNARE binding+++GO:0000822///inositol hexakisphosphate binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0032050///clathrin heavy chain binding+++GO:0035615///clathrin adaptor activity+++GO:0042169///SH2 domain binding+++GO:0043274///phospholipase binding" GO:0006900///vesicle budding from membrane+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007409///axonogenesis+++GO:0015031///protein transport+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0030100///regulation of endocytosis+++GO:0048268///clathrin coat assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0048666///neuron development+++GO:0050772///positive regulation of axonogenesis+++GO:0051223///regulation of protein transport+++GO:0072583///clathrin-dependent endocytosis+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1900275///negative regulation of phospholipase C activity+++GO:1904006///negative regulation of phospholipase D activity+++GO:1905445///positive regulation of clathrin coat assembly+++GO:2000331///regulation of terminal button organization+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:2000809///positive regulation of synaptic vesicle clustering 20617 20617 'Snca' mRNA 121 111 142 5.91 5.45 7.47 5.88 5.79 5.79 6.276666667 5.82 138 134 133 124.6666667 135 0.749855753 0.097854522 05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0008021///synaptic vesicle+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016234///inclusion body+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031092///platelet alpha granule membrane+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0099512///supramolecular fiber GO:0000149///SNARE binding+++GO:0000287///magnesium ion binding+++GO:0003779///actin binding+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008017///microtubule binding+++GO:0008198///ferrous iron binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0019894///kinesin binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030544///Hsp70 protein binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0043274///phospholipase binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0048156///tau protein binding+++GO:0048487///beta-tubulin binding+++GO:0050544///arachidonic acid binding+++GO:0051219///phosphoprotein binding+++GO:0070840///dynein complex binding+++GO:1903136///cuprous ion binding "GO:0001774///microglial cell activation+++GO:0001921///positive regulation of receptor recycling+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0001963///synaptic transmission, dopaminergic+++GO:0006631///fatty acid metabolic process+++GO:0006638///neutral lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007006///mitochondrial membrane organization+++GO:0007268///chemical synaptic transmission+++GO:0007568///aging+++GO:0008344///adult locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0010040///response to iron(II) ion+++GO:0010517///regulation of phospholipase activity+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0014048///regulation of glutamate secretion+++GO:0014059///regulation of dopamine secretion+++GO:0016079///synaptic vesicle exocytosis+++GO:0016082///synaptic vesicle priming+++GO:0022898///regulation of transmembrane transporter activity+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031623///receptor internalization+++GO:0031648///protein destabilization+++GO:0032026///response to magnesium ion+++GO:0032410///negative regulation of transporter activity+++GO:0032496///response to lipopolysaccharide+++GO:0032769///negative regulation of monooxygenase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034341///response to interferon-gamma+++GO:0034599///cellular response to oxidative stress+++GO:0035067///negative regulation of histone acetylation+++GO:0035493///SNARE complex assembly+++GO:0035543///positive regulation of SNARE complex assembly+++GO:0040012///regulation of locomotion+++GO:0042220///response to cocaine+++GO:0042416///dopamine biosynthetic process+++GO:0042417///dopamine metabolic process+++GO:0042493///response to drug+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0043030///regulation of macrophage activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045807///positive regulation of endocytosis+++GO:0045920///negative regulation of exocytosis+++GO:0045921///positive regulation of exocytosis+++GO:0045963///negative regulation of dopamine metabolic process+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048148///behavioral response to cocaine+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048488///synaptic vesicle endocytosis+++GO:0048489///synaptic vesicle transport+++GO:0050729///positive regulation of inflammatory response+++GO:0050806///positive regulation of synaptic transmission+++GO:0050808///synapse organization+++GO:0050812///regulation of acyl-CoA biosynthetic process+++GO:0051259///protein complex oligomerization+++GO:0051262///protein tetramerization+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051585///negative regulation of dopamine uptake involved in synaptic transmission+++GO:0051612///negative regulation of serotonin uptake+++GO:0051621///regulation of norepinephrine uptake+++GO:0051622///negative regulation of norepinephrine uptake+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0061024///membrane organization+++GO:0070495///negative regulation of thrombin-activated receptor signaling pathway+++GO:0070555///response to interleukin-1+++GO:0071280///cellular response to copper ion+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1903284///positive regulation of glutathione peroxidase activity+++GO:1903285///positive regulation of hydrogen peroxide catabolic process+++GO:1904307///response to desipramine+++GO:1904715///negative regulation of chaperone-mediated autophagy+++GO:1905606///regulation of presynapse assembly+++GO:2000377///regulation of reactive oxygen species metabolic process" 20618 20618 'Sncg' mRNA 790 739 755 75.82 70.39 76.91 57.74 52.69 57.75 74.37333333 56.06 688 611 664 761.3333333 654.3333333 0.0357901 -0.231665789 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding+++GO:1903136///cuprous ion binding GO:0007268///chemical synaptic transmission+++GO:0008344///adult locomotory behavior+++GO:0009306///protein secretion+++GO:0014059///regulation of dopamine secretion+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048488///synaptic vesicle endocytosis+++GO:0050808///synapse organization+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death 20619 20619 'Snap23' mRNA 861.03 769.01 859.24 20.75 18.45 22.18 40.37 39.15 37.99 20.46 39.17 1882 1804.79 1709.03 829.76 1798.606667 1.79E-34 1.101759414 04130///SNARE interactions in vesicular transport+++04611///Platelet activation GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0042581///specific granule+++GO:0042582///azurophil granule+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding GO:0002553///histamine secretion by mast cell+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016082///synaptic vesicle priming+++GO:0016192///vesicle-mediated transport+++GO:0017157///regulation of exocytosis+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0061025///membrane fusion+++GO:0065003///protein-containing complex assembly+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse 20620 20620 'Plk2' mRNA 304 350 321 5.99 6.79 6.71 31.48 33.44 28.72 6.496666667 31.21333333 1838 1907 1624 325 1789.666667 4.15E-128 2.449985953 04068///FoxO signaling pathway GO:0000785///chromatin+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043008///ATP-dependent protein binding+++GO:0044877///protein-containing complex binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007052///mitotic spindle organization+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0007613///memory+++GO:0010508///positive regulation of autophagy+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032465///regulation of cytokinesis+++GO:0032486///Rap protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0046599///regulation of centriole replication+++GO:0048167///regulation of synaptic plasticity+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0061000///negative regulation of dendritic spine development+++GO:0071866///negative regulation of apoptotic process in bone marrow+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:2000773///negative regulation of cellular senescence 20621 20621 'Snn' mRNA 836 897 336 15.85 16.74 6.76 6.69 5.74 6.42 13.11666667 6.283333333 406 340 377 689.6666667 374.3333333 0.046200137 -0.874756858 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding GO:0008150///biological_process 20623 20623 'Snrk' mRNA 1468 1576 1576 16.06 17.05 18.32 14.57 13.24 13.74 17.14333333 13.85 1550 1352 1397 1540 1433 0.225516603 -0.118229603 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 20624 20624 'Eftud2' mRNA 1668 1667 1765 27.31 26.86 30.67 27.78 26.61 27.31 28.28 27.23333333 1952 1826 1858 1700 1878.666667 0.146561875 0.129764275 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030623///U5 snRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006414///translational elongation+++GO:0008380///RNA splicing+++GO:0035690///cellular response to drug+++GO:0042220///response to cocaine" 20630 20630 'Snrpc' mRNA 889 784 855 80.88 70.74 82.61 90.9 103.05 94.1 78.07666667 96.01666667 1145 1262 1142 842.6666667 1183 3.09E-06 0.476969106 03040///Spliceosome GO:0000243///commitment complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005685///U1 snRNP+++GO:0015030///Cajal body+++GO:0071004///U2-type prespliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0030619///U1 snRNA binding+++GO:0030627///pre-mRNA 5'-splice site binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000395///mRNA 5'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome" 20637 20637 'Snrnp70' mRNA 3887 3796 2409 78.45 71.37 55.62 64.91 60.81 60.68 68.48 62.13333333 2992 2618 2629 3364 2746.333333 0.152454433 -0.295424059 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005685///U1 snRNP+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0017069///snRNA binding+++GO:0030619///U1 snRNA binding+++GO:1990446///U1 snRNP binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0043484///regulation of RNA splicing+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 20638 20638 'Snrpb' mRNA 4913 4954 4737 271.29 271.06 277.9 291.51 306.88 299.85 273.4166667 299.4133333 6043 6204 6009 4868 6085.333333 5.32E-08 0.310737218 03040///Spliceosome+++05322///Systemic lupus erythematosus GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005683///U7 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034709///methylosome+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071204///histone pre-mRNA 3'end processing complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0070034///telomerase RNA binding+++GO:0071208///histone pre-mRNA DCP binding+++GO:1990446///U1 snRNP binding+++GO:1990447///U2 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006479///protein methylation+++GO:0007420///brain development+++GO:0008380///RNA splicing" 20639 20639 'Snrpb2' mRNA 558 503 551 27.73 24.68 29.05 41 43.46 42.89 27.15333333 42.45 947 979 958 537.3333333 961.3333333 2.57E-15 0.826226596 03040///Spliceosome GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030619///U1 snRNA binding+++GO:0070990///snRNP binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 20641 20641 'Snrpd1' mRNA 728 658 733 58.4 52.3 62.4 82.68 82.87 83.44 57.7 82.99666667 1180 1152 1150 706.3333333 1160.666667 6.30E-13 0.702532456 03040///Spliceosome+++05322///Systemic lupus erythematosus GO:0000243///commitment complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0097526///spliceosomal tri-snRNP complex GO:0003723///RNA binding+++GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 20643 20643 'Snrpe' mRNA 709 716 818 123.43 124.75 151.22 183.05 216.36 197.65 133.1333333 199.02 1195 1370 1241 747.6666667 1268.666667 1.26E-11 0.748466957 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005683///U7 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding+++GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0042633///hair cycle" 20646 20646 'Snrpn' mRNA 942.62 963.64 928.43 26.46 26.67 27.68 15.31 16.83 15.65 26.93666667 15.93 626.06 670.99 619.56 944.8966667 638.87 4.69E-09 -0.576272328 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005682///U5 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005737///cytoplasm+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071004///U2-type prespliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0009725///response to hormone" 20648 20648 'Snta1' mRNA 1497 1578 340 40.06 41.59 9.65 8.05 11.37 16.81 30.43333333 12.07666667 346 477 699 1138.333333 507.3333333 0.135073354 -1.145333224 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0017080///sodium channel regulator activity+++GO:0030165///PDZ domain binding+++GO:0044325///ion channel binding+++GO:0050998///nitric-oxide synthase binding+++GO:0051117///ATPase binding GO:0002027///regulation of heart rate+++GO:0003117///regulation of vasoconstriction by circulating norepinephrine+++GO:0007528///neuromuscular junction development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1902305///regulation of sodium ion transmembrane transport 20649 20649 'Sntb1' mRNA 1145 1088 1080 13.84 14.35 14.38 4.95 5.37 5.38 14.19 5.233333333 478 487 502 1104.333333 489 9.17E-35 -1.18691689 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0030165///PDZ domain binding 20650 20650 'Sntb2' mRNA 533 522 253 6.4 6.16 3.23 4.62 3.9 5.18 5.263333333 4.566666667 443 365 481 436 429.6666667 0.945211227 -0.019213965 GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding 20652 20652 'Soat1' mRNA 1311.6 1319.32 1192.29 14.69 14.52 14.2 41.7 40.82 41.5 14.47 41.34 4287.85 4099.17 4132.57 1274.403333 4173.196667 4.07E-169 1.700994533 00100///Steroid biosynthesis+++04979///Cholesterol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0004772///sterol O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0034736///cholesterol O-acyltransferase activity+++GO:0042802///identical protein binding" GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010742///macrophage derived foam cell differentiation+++GO:0010878///cholesterol storage+++GO:0033344///cholesterol efflux+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0034435///cholesterol esterification+++GO:0042632///cholesterol homeostasis+++GO:0042986///positive regulation of amyloid precursor protein biosynthetic process 20655 20655 'Sod1' mRNA 10960.34 10729.31 10903.37 1279.22 1245.51 1350.74 983.33 1012.55 1044.84 1291.823333 1013.573333 9619.39 9631.57 9854.54 10864.34 9701.833333 0.003395922 -0.176058719 04146///Peroxisome+++04213///Longevity regulating pathway - multiple species+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030141///secretory granule+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:1904115///axon cytoplasm GO:0004784///superoxide dismutase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0030346///protein phosphatase 2B binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0000187///activation of MAPK activity+++GO:0000302///response to reactive oxygen species+++GO:0000303///response to superoxide+++GO:0001541///ovarian follicle development+++GO:0001819///positive regulation of cytokine production+++GO:0001895///retina homeostasis+++GO:0001975///response to amphetamine+++GO:0002262///myeloid cell homeostasis+++GO:0006749///glutathione metabolic process+++GO:0006801///superoxide metabolic process+++GO:0006879///cellular iron ion homeostasis+++GO:0006979///response to oxidative stress+++GO:0007283///spermatogenesis+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0007569///cell aging+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0008089///anterograde axonal transport+++GO:0008090///retrograde axonal transport+++GO:0008217///regulation of blood pressure+++GO:0009408///response to heat+++GO:0009410///response to xenobiotic stimulus+++GO:0010033///response to organic substance+++GO:0019226///transmission of nerve impulse+++GO:0019430///removal of superoxide radicals+++GO:0031667///response to nutrient levels+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034465///response to carbon monoxide+++GO:0034599///cellular response to oxidative stress+++GO:0035865///cellular response to potassium ion+++GO:0040014///regulation of multicellular organism growth+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042554///superoxide anion generation+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043087///regulation of GTPase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045471///response to ethanol+++GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0045859///regulation of protein kinase activity+++GO:0046677///response to antibiotic+++GO:0046688///response to copper ion+++GO:0046716///muscle cell cellular homeostasis+++GO:0048678///response to axon injury+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0050728///negative regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060047///heart contraction+++GO:0060052///neurofilament cytoskeleton organization+++GO:0060087///relaxation of vascular smooth muscle+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0071276///cellular response to cadmium ion+++GO:0071318///cellular response to ATP+++GO:0072593///reactive oxygen species metabolic process+++GO:0097332///response to antipsychotic drug+++GO:1902177///positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 20656 20656 'Sod2' mRNA 3719.74 3656.67 3849.85 52.63 50.9 57.78 55.14 52.07 55.59 53.77 54.26666667 4485.12 4137.01 4379.41 3742.086667 4333.846667 0.005639225 0.197658435 04013///MAPK signaling pathway - fly+++04068///FoxO signaling pathway+++04146///Peroxisome+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++05016///Huntington disease+++05208///Chemical carcinogenesis - reactive oxygen species+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath GO:0003677///DNA binding+++GO:0004784///superoxide dismutase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0019825///oxygen binding+++GO:0019899///enzyme binding+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000302///response to reactive oxygen species+++GO:0000303///response to superoxide+++GO:0001306///age-dependent response to oxidative stress+++GO:0001315///age-dependent response to reactive oxygen species+++GO:0001666///response to hypoxia+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001889///liver development+++GO:0003032///detection of oxygen+++GO:0003069///acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006749///glutathione metabolic process+++GO:0006801///superoxide metabolic process+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0007507///heart development+++GO:0007568///aging+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0008217///regulation of blood pressure+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0008637///apoptotic mitochondrial changes+++GO:0009314///response to radiation+++GO:0009409///response to cold+++GO:0009410///response to xenobiotic stimulus+++GO:0009791///post-embryonic development+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0010269///response to selenium ion+++GO:0010332///response to gamma radiation+++GO:0010729///positive regulation of hydrogen peroxide biosynthetic process+++GO:0014823///response to activity+++GO:0019430///removal of superoxide radicals+++GO:0022904///respiratory electron transport chain+++GO:0030097///hemopoiesis+++GO:0030335///positive regulation of cell migration+++GO:0031667///response to nutrient levels+++GO:0032364///oxygen homeostasis+++GO:0032496///response to lipopolysaccharide+++GO:0033591///response to L-ascorbic acid+++GO:0034021///response to silicon dioxide+++GO:0035900///response to isolation stress+++GO:0035902///response to immobilization stress+++GO:0042311///vasodilation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042554///superoxide anion generation+++GO:0042743///hydrogen peroxide metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0046686///response to cadmium ion+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048666///neuron development+++GO:0048678///response to axon injury+++GO:0048773///erythrophore differentiation+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0051289///protein homotetramerization+++GO:0051602///response to electrical stimulus+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0055072///iron ion homeostasis+++GO:0055093///response to hyperoxia+++GO:0071000///response to magnetism+++GO:0071361///cellular response to ethanol+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1902631///negative regulation of membrane hyperpolarization+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:1905932///positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching 20657 20657 'Sod3' mRNA 4335 4215 4046 120.4 115.32 119.21 73.05 73.24 71.05 118.31 72.44666667 3024 2960 2847 4198.666667 2943.666667 1.30E-18 -0.523883395 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0062023///collagen-containing extracellular matrix GO:0004784///superoxide dismutase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0006801///superoxide metabolic process+++GO:0006979///response to oxidative stress+++GO:0019430///removal of superoxide radicals+++GO:0046688///response to copper ion+++GO:0097746///regulation of blood vessel diameter 20658 20658 'Son' mRNA 8117.96 8392 9397 50.94 51.67 62.86 34.69 33.62 34.82 55.15666667 34.37666667 6355 6004.95 6179.95 8635.653333 6179.966667 1.39E-10 -0.499398748 GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0050733///RS domain binding "GO:0000226///microtubule cytoskeleton organization+++GO:0000281///mitotic cytokinesis+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0043066///negative regulation of apoptotic process+++GO:0043484///regulation of RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0051726///regulation of cell cycle" 20660 20660 'Sorl1' mRNA 7386 7510 7183 36.04 36.02 37.14 19.11 17.88 19.39 36.4 18.79333333 4459 4115 4392 7359.666667 4322 5.51E-47 -0.780218086 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005641///nuclear envelope lumen+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031985///Golgi cisterna+++GO:0032585///multivesicular body membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0097356///perinucleolar compartment GO:0001540///amyloid-beta binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0031267///small GTPase binding+++GO:0042923///neuropeptide binding GO:0002024///diet induced thermogenesis+++GO:0006605///protein targeting+++GO:0006622///protein targeting to lysosome+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007218///neuropeptide signaling pathway+++GO:0007275///multicellular organism development+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0014910///regulation of smooth muscle cell migration+++GO:0016477///cell migration+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031333///negative regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0034067///protein localization to Golgi apparatus+++GO:0038020///insulin receptor recycling+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045053///protein retention in Golgi apparatus+++GO:0045732///positive regulation of protein catabolic process+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0050768///negative regulation of neurogenesis+++GO:0051604///protein maturation+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:1900168///positive regulation of glial cell-derived neurotrophic factor secretion+++GO:1901215///negative regulation of neuron death+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902771///positive regulation of choline O-acetyltransferase activity+++GO:1902948///negative regulation of tau-protein kinase activity+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport+++GO:1902955///positive regulation of early endosome to recycling endosome transport+++GO:1902960///negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1902963///negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1902997///negative regulation of neurofibrillary tangle assembly+++GO:1904179///positive regulation of adipose tissue development+++GO:1990845///adaptive thermogenesis+++GO:2001137///positive regulation of endocytic recycling 20661 20661 'Sort1' mRNA 1930 1714 1677 15.14 13.17 13.97 10.87 8.9 9.87 14.09333333 9.88 1597 1276 1410 1773.666667 1427.666667 3.93E-04 -0.326012668 04142///Lysosome+++04722///Neurotrophin signaling pathway+++04979///Cholesterol metabolism GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0032580///Golgi cisterna membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0005515///protein binding+++GO:0010465///nerve growth factor receptor activity+++GO:0019899///enzyme binding+++GO:0030379///neurotensin receptor activity, non-G protein-coupled+++GO:0048406///nerve growth factor binding+++GO:1905394///retromer complex binding" GO:0001503///ossification+++GO:0006622///protein targeting to lysosome+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0006895///Golgi to endosome transport+++GO:0006897///endocytosis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007275///multicellular organism development+++GO:0008333///endosome to lysosome transport+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010468///regulation of gene expression+++GO:0014902///myotube differentiation+++GO:0016050///vesicle organization+++GO:0030154///cell differentiation+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0032868///response to insulin+++GO:0038180///nerve growth factor signaling pathway+++GO:0045599///negative regulation of fat cell differentiation+++GO:0046323///glucose import+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048227///plasma membrane to endosome transport+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0090160///Golgi to lysosome transport+++GO:1904037///positive regulation of epithelial cell apoptotic process 20662 20662 'Sos1' mRNA 514 489 492 3.62 3.42 3.63 3.37 3.05 3.05 3.556666667 3.156666667 549 476 480 498.3333333 501.6666667 0.988201161 -0.003692192 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04320///Dorso-ventral axis formation+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05231///Choline metabolism in cancer" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0046982///protein heterodimerization activity GO:0001782///B cell homeostasis+++GO:0001942///hair follicle development+++GO:0002260///lymphocyte homeostasis+++GO:0003007///heart morphogenesis+++GO:0003209///cardiac atrium morphogenesis+++GO:0003344///pericardium morphogenesis+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007296///vitellogenesis+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0035264///multicellular organism growth+++GO:0042129///regulation of T cell proliferation+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0060021///roof of mouth development+++GO:0061029///eyelid development in camera-type eye+++GO:0061384///heart trabecula morphogenesis+++GO:1904693///midbrain morphogenesis+++GO:2000973///regulation of pro-B cell differentiation 20663 20663 'Sos2' mRNA 495 518 487 4.88 5.02 5.1 3.86 3.46 3.96 5 3.76 450 393 449 500 430.6666667 0.083727325 -0.227595948 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04072///Phospholipase D signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04320///Dorso-ventral axis formation+++04510///Focal adhesion+++04540///Gap junction+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05231///Choline metabolism in cancer" GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0001782///B cell homeostasis+++GO:0002260///lymphocyte homeostasis+++GO:0007264///small GTPase mediated signal transduction+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0042129///regulation of T cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:2000973///regulation of pro-B cell differentiation 20664 20664 'Sox1' mRNA 139 150 118 1.86 1.97 1.67 0.49 0.57 0.61 1.833333333 0.556666667 42 48 51 135.6666667 47 6.69E-09 -1.536196031 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0009653///anatomical structure morphogenesis+++GO:0021521///ventral spinal cord interneuron specification+++GO:0021879///forebrain neuron differentiation+++GO:0021884///forebrain neuron development+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:1904936///interneuron migration+++GO:1990830///cellular response to leukemia inhibitory factor" 20665 20665 'Sox10' mRNA 5250 4981 2757 107.09 100.01 59.66 29.05 30.38 31.57 88.92 30.33333333 1638 1673 1724 4329.333333 1678.333333 2.05E-07 -1.364809994 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0031315///extrinsic component of mitochondrial outer membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001755///neural crest cell migration+++GO:0001942///hair follicle development+++GO:0002009///morphogenesis of an epithelium+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0007422///peripheral nervous system development+++GO:0009653///anatomical structure morphogenesis+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0014015///positive regulation of gliogenesis+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0030318///melanocyte differentiation+++GO:0031643///positive regulation of myelination+++GO:0032808///lacrimal gland development+++GO:0035690///cellular response to drug+++GO:0042633///hair cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0043588///skin development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048484///enteric nervous system development+++GO:0048546///digestive tract morphogenesis+++GO:0048589///developmental growth+++GO:0048709///oligodendrocyte differentiation+++GO:0048863///stem cell differentiation+++GO:0061138///morphogenesis of a branching epithelium+++GO:0071393///cellular response to progesterone stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 20666 20666 'Sox11' mRNA 120 93 114 0.75 0.57 0.75 0.78 0.62 0.64 0.69 0.68 145 112 114 109 123.6666667 0.589925807 0.165428782 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001822///kidney development+++GO:0001841///neural tube formation+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0003151///outflow tract morphogenesis+++GO:0003211///cardiac ventricle formation+++GO:0003357///noradrenergic neuron differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0014009///glial cell proliferation+++GO:0014032///neural crest cell development+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0021510///spinal cord development+++GO:0021782///glial cell development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0035332///positive regulation of hippo signaling+++GO:0035914///skeletal muscle cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046887///positive regulation of hormone secretion+++GO:0048485///sympathetic nervous system development+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0060022///hard palate development+++GO:0060023///soft palate development+++GO:0060174///limb bud formation+++GO:0060253///negative regulation of glial cell proliferation+++GO:0060412///ventricular septum morphogenesis+++GO:0060425///lung morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060563///neuroepithelial cell differentiation+++GO:0061029///eyelid development in camera-type eye+++GO:0061053///somite development+++GO:0061303///cornea development in camera-type eye+++GO:0061386///closure of optic fissure+++GO:0072395///signal transduction involved in cell cycle checkpoint+++GO:2000648///positive regulation of stem cell proliferation+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2001111///positive regulation of lens epithelial cell proliferation" 20667 20667 'Sox12' mRNA 193 207 215 2.34 2.46 2.76 1.67 1.6 2.02 2.52 1.763333333 159 149 186 205 164.6666667 0.114429908 -0.329855848 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0021510///spinal cord development+++GO:0030154///cell differentiation+++GO:0045165///cell fate commitment+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 20668 20668 'Sox13' mRNA 1133 1131 1089 18.86 18.47 19.15 8.9 8.63 7.76 18.82666667 8.43 615 583 519 1117.666667 572.3333333 5.64E-24 -0.977821728 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021529///spinal cord oligodendrocyte cell differentiation+++GO:0030154///cell differentiation+++GO:0042492///gamma-delta T cell differentiation+++GO:0045165///cell fate commitment+++GO:0045586///regulation of gamma-delta T cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090336///positive regulation of brown fat cell differentiation" 20670 20670 'Sox15' mRNA 16 8 17 0.87 0.43 0.98 0.48 0.44 0.34 0.76 0.42 10 9 7 13.66666667 8.666666667 0.443632161 -0.680150126 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis+++GO:0014718///positive regulation of satellite cell activation involved in skeletal muscle regeneration+++GO:0030154///cell differentiation+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048627///myoblast development+++GO:0060707///trophoblast giant cell differentiation+++GO:0070318///positive regulation of G0 to G1 transition+++GO:2000288///positive regulation of myoblast proliferation" 20671 20671 'Sox17' mRNA 229 267 232 4.23 4.97 4.82 3.35 3.42 3.26 4.673333333 3.343333333 230 216 194 242.6666667 213.3333333 0.313733413 -0.197070324 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding" "GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001656///metanephros development+++GO:0001706///endoderm formation+++GO:0001714///endodermal cell fate specification+++GO:0001828///inner cell mass cellular morphogenesis+++GO:0001947///heart looping+++GO:0003142///cardiogenic plate morphogenesis+++GO:0003143///embryonic heart tube morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003308///negative regulation of Wnt signaling pathway involved in heart development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007369///gastrulation+++GO:0007492///endoderm development+++GO:0007493///endodermal cell fate determination+++GO:0007507///heart development+++GO:0009653///anatomical structure morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0021903///rostrocaudal neural tube patterning+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0031648///protein destabilization+++GO:0035050///embryonic heart tube development+++GO:0042074///cell migration involved in gastrulation+++GO:0045595///regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045995///regulation of embryonic development+++GO:0048568///embryonic organ development+++GO:0048617///embryonic foregut morphogenesis+++GO:0048863///stem cell differentiation+++GO:0048866///stem cell fate specification+++GO:0050821///protein stabilization+++GO:0060214///endocardium formation+++GO:0060913///cardiac cell fate determination+++GO:0060956///endocardial cell differentiation+++GO:0061009///common bile duct development+++GO:0061010///gall bladder development+++GO:0061031///endodermal digestive tract morphogenesis+++GO:0072091///regulation of stem cell proliferation+++GO:0072189///ureter development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000035///regulation of stem cell division+++GO:2000043///regulation of cardiac cell fate specification" 20672 20672 'Sox18' mRNA 156 131 150 5.63 4.66 5.74 8.39 9.08 8.25 5.343333333 8.573333333 267 282 254 145.6666667 267.6666667 1.81E-06 0.864715024 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001942///hair follicle development+++GO:0001944///vasculature development+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007507///heart development+++GO:0009653///anatomical structure morphogenesis+++GO:0022405///hair cycle process+++GO:0030154///cell differentiation+++GO:0035050///embryonic heart tube development+++GO:0043534///blood vessel endothelial cell migration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0048866///stem cell fate specification+++GO:0060214///endocardium formation+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060956///endocardial cell differentiation+++GO:0061028///establishment of endothelial barrier+++GO:0072091///regulation of stem cell proliferation" 20674 20674 'Sox2' mRNA 386 384 293 8.73 8.55 7.03 2.69 1.37 1.52 8.103333333 1.86 137 68 75 354.3333333 93.33333333 3.57E-18 -1.936802964 04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031490///chromatin DNA binding+++GO:0035198///miRNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0001654///eye development+++GO:0001708///cell fate specification+++GO:0001714///endodermal cell fate specification+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007050///cell cycle arrest+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0009611///response to wounding+++GO:0009653///anatomical structure morphogenesis+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0021879///forebrain neuron differentiation+++GO:0021983///pituitary gland development+++GO:0021984///adenohypophysis development+++GO:0021987///cerebral cortex development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030539///male genitalia development+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0030900///forebrain development+++GO:0030910///olfactory placode formation+++GO:0032526///response to retinoic acid+++GO:0035019///somatic stem cell population maintenance+++GO:0042246///tissue regeneration+++GO:0042472///inner ear morphogenesis+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043586///tongue development+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045597///positive regulation of cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046148///pigment biosynthetic process+++GO:0048286///lung alveolus development+++GO:0048568///embryonic organ development+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048663///neuron fate commitment+++GO:0048839///inner ear development+++GO:0048852///diencephalon morphogenesis+++GO:0048863///stem cell differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0050973///detection of mechanical stimulus involved in equilibrioception+++GO:0051726///regulation of cell cycle+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060235///lens induction in camera-type eye+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0070848///response to growth factor+++GO:0071276///cellular response to cadmium ion+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097150///neuronal stem cell population maintenance" 20677 20677 'Sox4' mRNA 449 467 347 5.03 5.14 4.12 5.38 4.96 6 4.763333333 5.446666667 553 498 598 421 549.6666667 0.005695235 0.377721993 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0035198///miRNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0001666///response to hypoxia+++GO:0001841///neural tube formation+++GO:0002328///pro-B cell differentiation+++GO:0003183///mitral valve morphogenesis+++GO:0003211///cardiac ventricle formation+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003289///atrial septum primum morphogenesis+++GO:0003357///noradrenergic neuron differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0014009///glial cell proliferation+++GO:0021510///spinal cord development+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021782///glial cell development+++GO:0030154///cell differentiation+++GO:0030217///T cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032024///positive regulation of insulin secretion+++GO:0035019///somatic stem cell population maintenance+++GO:0035910///ascending aorta morphogenesis+++GO:0042593///glucose homeostasis+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0043065///positive regulation of apoptotic process+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045727///positive regulation of translation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048485///sympathetic nervous system development+++GO:0050821///protein stabilization+++GO:0060174///limb bud formation+++GO:0060412///ventricular septum morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060563///neuroepithelial cell differentiation+++GO:0060993///kidney morphogenesis+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0071333///cellular response to glucose stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000761///positive regulation of N-terminal peptidyl-lysine acetylation" 20678 20678 'Sox5' mRNA 1363.91 1439.27 1201.01 6.83 7.13 6.38 3.29 2.68 2.75 6.78 2.906666667 807.84 642.6 666.73 1334.73 705.7233333 1.03E-21 -0.931210899 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0001502///cartilage condensation+++GO:0001701///in utero embryonic development+++GO:0002062///chondrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021953///central nervous system neuron differentiation+++GO:0030154///cell differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0045165///cell fate commitment+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048709///oligodendrocyte differentiation+++GO:0051216///cartilage development+++GO:0055059///asymmetric neuroblast division+++GO:0060164///regulation of timing of neuron differentiation+++GO:0061036///positive regulation of cartilage development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2000741///positive regulation of mesenchymal stem cell differentiation" 20679 20679 'Sox6' mRNA 1790.12 1907.7 1519.3 15.24 16.95 13.61 5.53 6.08 5.66 15.26666667 5.756666667 913.47 852.31 813.96 1739.04 859.9133333 4.92E-33 -1.025155328 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001502///cartilage condensation+++GO:0001701///in utero embryonic development+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0016458///gene silencing+++GO:0021529///spinal cord oligodendrocyte cell differentiation+++GO:0021778///oligodendrocyte cell fate specification+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0042692///muscle cell differentiation+++GO:0045165///cell fate commitment+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048708///astrocyte differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0048821///erythrocyte development+++GO:0051216///cartilage development+++GO:0055007///cardiac muscle cell differentiation+++GO:0061036///positive regulation of cartilage development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:2000741///positive regulation of mesenchymal stem cell differentiation" 20680 20680 'Sox7' mRNA 50 52 62 0.84 0.86 1.1 1.6 1.53 1.44 0.933333333 1.523333333 110 103 96 54.66666667 103 0.001938153 0.897538951 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001706///endoderm formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060828///regulation of canonical Wnt signaling pathway" 20681 20681 'Sox8' mRNA 3677 3560 3422 67.22 64.03 66.3 32.7 32.08 33.67 65.85 32.81666667 2060 1973 2051 3553 2028 3.20E-40 -0.820577763 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001755///neural crest cell migration+++GO:0002009///morphogenesis of an epithelium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0007422///peripheral nervous system development+++GO:0008584///male gonad development+++GO:0010628///positive regulation of gene expression+++GO:0010817///regulation of hormone levels+++GO:0014015///positive regulation of gliogenesis+++GO:0014032///neural crest cell development+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0035914///skeletal muscle cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045165///cell fate commitment+++GO:0045444///fat cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0048469///cell maturation+++GO:0048484///enteric nervous system development+++GO:0048709///oligodendrocyte differentiation+++GO:0060009///Sertoli cell development+++GO:0060018///astrocyte fate commitment+++GO:0060041///retina development in camera-type eye+++GO:0060221///retinal rod cell differentiation+++GO:0060612///adipose tissue development+++GO:0061138///morphogenesis of a branching epithelium+++GO:0072034///renal vesicle induction+++GO:0072197///ureter morphogenesis+++GO:0072289///metanephric nephron tubule formation+++GO:0090184///positive regulation of kidney development+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis" 20682 20682 'Sox9' mRNA 9011 9037 8470 117.11 115.51 116.76 65.41 62.24 62.37 116.46 63.34 5793 5385 5350 8839.333333 5509.333333 2.48E-42 -0.693811553 04024///cAMP signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0097157///pre-mRNA intronic binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001708///cell fate specification+++GO:0001837///epithelial to mesenchymal transition+++GO:0001894///tissue homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0002009///morphogenesis of an epithelium+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002062///chondrocyte differentiation+++GO:0002063///chondrocyte development+++GO:0002683///negative regulation of immune system process+++GO:0003170///heart valve development+++GO:0003179///heart valve morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003188///heart valve formation+++GO:0003203///endocardial cushion morphogenesis+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0003415///chondrocyte hypertrophy+++GO:0003430///growth plate cartilage chondrocyte growth+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0007283///spermatogenesis+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0010468///regulation of gene expression+++GO:0010564///regulation of cell cycle process+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0014032///neural crest cell development+++GO:0014036///neural crest cell fate specification+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0019100///male germ-line sex determination+++GO:0019933///cAMP-mediated signaling+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030238///male sex determination+++GO:0030279///negative regulation of ossification+++GO:0030502///negative regulation of bone mineralization+++GO:0030850///prostate gland development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0030879///mammary gland development+++GO:0030903///notochord development+++GO:0030916///otic vesicle formation+++GO:0031018///endocrine pancreas development+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032808///lacrimal gland development+++GO:0034504///protein localization to nucleus+++GO:0035019///somatic stem cell population maintenance+++GO:0035622///intrahepatic bile duct development+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0045165///cell fate commitment+++GO:0045595///regulation of cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051216///cartilage development+++GO:0060008///Sertoli cell differentiation+++GO:0060009///Sertoli cell development+++GO:0060018///astrocyte fate commitment+++GO:0060041///retina development in camera-type eye+++GO:0060174///limb bud formation+++GO:0060221///retinal rod cell differentiation+++GO:0060350///endochondral bone morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060487///lung epithelial cell differentiation+++GO:0060512///prostate gland morphogenesis+++GO:0060517///epithelial cell proliferation involved in prostatic bud elongation+++GO:0060532///bronchus cartilage development+++GO:0060534///trachea cartilage development+++GO:0060729///intestinal epithelial structure maintenance+++GO:0060784///regulation of cell proliferation involved in tissue homeostasis+++GO:0061036///positive regulation of cartilage development+++GO:0061046///regulation of branching involved in lung morphogenesis+++GO:0061138///morphogenesis of a branching epithelium+++GO:0061145///lung smooth muscle development+++GO:0065003///protein-containing complex assembly+++GO:0070168///negative regulation of biomineral tissue development+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070384///Harderian gland development+++GO:0070542///response to fatty acid+++GO:0071260///cellular response to mechanical stimulus+++GO:0071300///cellular response to retinoic acid+++GO:0071347///cellular response to interleukin-1+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071504///cellular response to heparin+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071599///otic vesicle development+++GO:0071773///cellular response to BMP stimulus+++GO:0072034///renal vesicle induction+++GO:0072170///metanephric tubule development+++GO:0072189///ureter development+++GO:0072190///ureter urothelium development+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0072197///ureter morphogenesis+++GO:0072289///metanephric nephron tubule formation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0090184///positive regulation of kidney development+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0097065///anterior head development+++GO:0098609///cell-cell adhesion+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:1902732///positive regulation of chondrocyte proliferation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904864///negative regulation of beta-catenin-TCF complex assembly+++GO:2000020///positive regulation of male gonad development+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis+++GO:2000741///positive regulation of mesenchymal stem cell differentiation+++GO:2000794///regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:2001054///negative regulation of mesenchymal cell apoptotic process" 20683 20683 'Sp1' mRNA 531 532 544 3.58 3.52 3.89 4.72 3.92 4.21 3.663333333 4.283333333 807 655 698 535.6666667 720 4.21E-04 0.411999735 "01522///Endocrine resistance+++04137///Mitophagy - animal+++04350///TGF-beta signaling pathway+++04915///Estrogen signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05224///Breast cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy" GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0035035///histone acetyltransferase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001503///ossification+++GO:0001701///in utero embryonic development+++GO:0001829///trophectodermal cell differentiation+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0016032///viral process+++GO:0030219///megakaryocyte differentiation+++GO:0030324///lung development+++GO:0032869///cellular response to insulin stimulus+++GO:0033194///response to hydroperoxide+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043353///enucleate erythrocyte differentiation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043923///positive regulation by host of viral transcription+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0060136///embryonic process involved in female pregnancy+++GO:0060216///definitive hemopoiesis+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1904828///positive regulation of hydrogen sulfide biosynthetic process+++GO:1905564///positive regulation of vascular endothelial cell proliferation" 20684 20684 'Sp100' mRNA 431.38 493.7 450.8 10.08 11.5 11.2 36.05 37.6 38.32 10.92666667 37.32333333 1813.68 1818.06 1826.03 458.6266667 1819.256667 6.49E-112 1.978625092 05168///Herpes simplex virus 1 infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030870///Mre11 complex+++GO:0034399///nuclear periphery "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0070087///chromo shadow domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000723///telomere maintenance+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0010596///negative regulation of endothelial cell migration+++GO:0032526///response to retinoic acid+++GO:0032897///negative regulation of viral transcription+++GO:0034097///response to cytokine+++GO:0034340///response to type I interferon+++GO:0034341///response to interferon-gamma+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045185///maintenance of protein location+++GO:0045765///regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046826///negative regulation of protein export from nucleus+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051271///negative regulation of cellular component movement+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902044///regulation of Fas signaling pathway" 20686 20686 'Spa17' mRNA 274 253 257 27.95 25.28 27.55 9.2 8.57 6.49 26.92666667 8.086666667 101 93 72 261.3333333 88.66666667 2.43E-15 -1.572610126 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0097228///sperm principal piece GO:0005516///calmodulin binding GO:0007339///binding of sperm to zona pellucida 20687 20687 'Sp3' mRNA 1008 1053 942 13.13 13.55 12.98 14.93 14.29 13.73 13.22 14.31666667 1312 1228 1172 1001 1237.333333 6.94E-04 0.294812838 GO:0005634///nucleus+++GO:0016605///PML body+++GO:0017053///transcriptional repressor complex+++GO:0032993///protein-DNA complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001701///in utero embryonic development+++GO:0001779///natural killer cell differentiation+++GO:0001829///trophectodermal cell differentiation+++GO:0001889///liver development+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030224///monocyte differentiation+++GO:0030324///lung development+++GO:0030851///granulocyte differentiation+++GO:0043353///enucleate erythrocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0060136///embryonic process involved in female pregnancy+++GO:0060216///definitive hemopoiesis" 20688 20688 'Sp4' mRNA 763 885 784 4.91 5.54 5.38 2.17 2.05 1.87 5.276666667 2.03 396 348 325 810.6666667 356.3333333 5.36E-25 -1.197978998 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008016///regulation of heart contraction 20689 20689 'Sall3' mRNA 467 449 471 3.4 3.21 3.75 0.76 0.68 0.74 3.453333333 0.726666667 122 109 115 462.3333333 115.3333333 1.58E-38 -2.017061406 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021891///olfactory bulb interneuron development+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0045879///negative regulation of smoothened signaling pathway 20692 20692 'Sparc' mRNA 30957 32087 30470 650.22 663.44 678.91 935.07 943.64 943.59 664.19 940.7666667 51209 50467 50032 31171.33333 50569.33333 1.27E-50 0.686240074 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0031012///extracellular matrix+++GO:0031091///platelet alpha granule+++GO:0031092///platelet alpha granule membrane+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0098978///glutamatergic synapse GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding GO:0001503///ossification+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0007507///heart development+++GO:0009629///response to gravity+++GO:0010288///response to lead ion+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0022604///regulation of cell morphogenesis+++GO:0030324///lung development+++GO:0032496///response to lipopolysaccharide+++GO:0033591///response to L-ascorbic acid+++GO:0034097///response to cytokine+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0043473///pigmentation+++GO:0045471///response to ethanol+++GO:0046686///response to cadmium ion+++GO:0048839///inner ear development+++GO:0048856///anatomical structure development+++GO:0050807///regulation of synapse organization+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0060348///bone development+++GO:0071363///cellular response to growth factor stimulus 20698 20698 'Sphk1' mRNA 400 451 435 9.23 10.26 10.45 21.66 19.49 21.64 9.98 20.93 951 835 899 428.6666667 895 1.97E-22 1.048677284 00600///Sphingolipid metabolism+++04020///Calcium signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05152///Tuberculosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0031901///early endosome membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001727///lipid kinase activity+++GO:0003677///DNA binding+++GO:0003951///NAD+ kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0008481///sphinganine kinase activity+++GO:0016301///kinase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0017050///D-erythro-sphingosine kinase activity+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0051721///protein phosphatase 2A binding GO:0001568///blood vessel development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006473///protein acetylation+++GO:0006665///sphingolipid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0006954///inflammatory response+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0019371///cyclooxygenase pathway+++GO:0019722///calcium-mediated signaling+++GO:0030100///regulation of endocytosis+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0034612///response to tumor necrosis factor+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046512///sphingosine biosynthetic process+++GO:0046834///lipid phosphorylation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050764///regulation of phagocytosis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071363///cellular response to growth factor stimulus+++GO:0071897///DNA biosynthetic process+++GO:0090520///sphingolipid mediated signaling pathway+++GO:0150077///regulation of neuroinflammatory response+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903978///regulation of microglial cell activation+++GO:1905364///regulation of endosomal vesicle fusion 20700 20700 'Serpina1a' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006487///protein N-linked glycosylation+++GO:0006953///acute-phase response+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 20701 20701 'Serpina1b' mRNA 6 6.77 7 0.25 0.28 0.31 0.22 0.15 0.21 0.28 0.193333333 6 4.01 5.62 6.59 5.21 0.792992206 -0.359272358 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding GO:0001701///in utero embryonic development+++GO:0006487///protein N-linked glycosylation+++GO:0006953///acute-phase response+++GO:0010288///response to lead ion+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033986///response to methanol+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone+++GO:0046687///response to chromate+++GO:1900004///negative regulation of serine-type endopeptidase activity 20703 20703 'Serpina1d' mRNA 0 2.23 0 0 0.09 0 0 0.04 0 0.03 0.013333333 0 1 0 0.743333333 0.333333333 0.863090843 -0.864760308 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding GO:0006487///protein N-linked glycosylation+++GO:0006953///acute-phase response+++GO:0010288///response to lead ion+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033986///response to methanol+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone+++GO:0046687///response to chromate+++GO:1900004///negative regulation of serine-type endopeptidase activity 20706 20706 'Serpinb9b' mRNA 1 1 0 0.03 0.03 0 0.99 0.49 0.76 0.02 0.746666667 39 19 29 0.666666667 29 1.15E-05 5.431327884 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0001913///T cell mediated cytotoxicity+++GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033668///negative regulation by symbiont of host apoptotic process+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 20707 20707 'Serpinb9c' mRNA 1 0 2 0.03 0 0.06 0 0.08 0 0.03 0.026666667 0 3 0 1 1 0.998591786 -0.025841413 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033668///negative regulation by symbiont of host apoptotic process+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 20708 20708 'Serpinb6b' mRNA 62 67 67 1.64 1.9 1.95 3.75 3.73 3.6 1.83 3.693333333 155 149 142 65.33333333 148.6666667 1.03E-06 1.173317028 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0097180///serine protease inhibitor complex GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity GO:0007605///sensory perception of sound+++GO:0008406///gonad development+++GO:0010951///negative regulation of endopeptidase activity+++GO:0071470///cellular response to osmotic stress 20709 20709 'Serpinb9f' mRNA 5 1 5 0.15 0.03 0.16 0 0 0 0.113333333 0 0 0 0 3.666666667 0 0.059543789 -4.346117316 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033668///negative regulation by symbiont of host apoptotic process+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 20713 20713 'Serpini1' mRNA 125 154 134 2.16 2.61 2.45 1.53 1.61 1.47 2.406666667 1.536666667 102 105 95 137.6666667 100.6666667 0.057506377 -0.46238107 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle+++GO:0034774///secretory granule lumen+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0060205///cytoplasmic vesicle lumen GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0030155///regulation of cell adhesion 20715 20715 'Serpina3g' mRNA 69.69 90.03 98.03 2.31 2.85 3.74 7.89 8.39 7.33 2.966666667 7.87 274 280.05 245.77 85.91666667 266.6066667 3.51E-15 1.621238594 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 20716 20716 'Serpina3n' mRNA 374.04 421.99 389.1 10.13 11.27 11.19 45.72 46.4 46.79 10.86333333 46.30333333 1939.15 1922.85 1925.4 395.0433333 1929.133333 1.86E-148 2.277611243 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0006953///acute-phase response+++GO:0009617///response to bacterium+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 207165 207165 'Bptf' mRNA 2051 2052 1842 10.05 9.89 9.55 7.56 7.07 7.48 9.83 7.37 1790 1630 1719 1981.666667 1713 0.002420195 -0.220930908 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016589///NURF complex+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001892///embryonic placenta development+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007492///endoderm development+++GO:0009611///response to wounding+++GO:0009952///anterior/posterior pattern specification+++GO:0042766///nucleosome mobilization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990090///cellular response to nerve growth factor stimulus 20717 20717 'Serpina3m' mRNA 1 1 6.88 0.04 0.04 0.26 0.68 0.59 0.36 0.113333333 0.543333333 18.79 16.91 9.54 2.96 15.08 0.021001692 2.38568119 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 207175 207175 'Cetn4' mRNA 203.35 193.47 225.03 12.11 11.39 14.22 5.49 4.47 5.95 12.57333333 5.303333333 105.79 83.87 110.76 207.2833333 100.14 5.23E-07 -1.076060976 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body GO:0005509///calcium ion binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0032795///heterotrimeric G-protein binding GO:0000278///mitotic cell cycle+++GO:0007099///centriole replication 207181 207181 'Rbms3' mRNA 1882.85 1920.17 1849.45 12.23 12.28 12.7 7.39 6.35 7.09 12.40333333 6.943333333 1307.77 1098.24 1215.84 1884.156667 1207.283333 2.25E-16 -0.655696217 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding GO:0002357///defense response to tumor cell+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0045727///positive regulation of translation+++GO:0090090///negative regulation of canonical Wnt signaling pathway 207182 207182 'Ggt7' mRNA 419 554 500 8.87 11.57 11.22 5.04 5.49 4.99 10.55333333 5.173333333 274 291 262 491 275.6666667 1.11E-08 -0.844701959 00430///Taurine and hypotaurine metabolism+++00480///Glutathione metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000048///peptidyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0036374///glutathione hydrolase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0103068///leukotriene C4 gamma-glutamyl transferase activity" GO:0006412///translation+++GO:0006508///proteolysis+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006751///glutathione catabolic process+++GO:0007283///spermatogenesis+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034612///response to tumor necrosis factor+++GO:1902883///negative regulation of response to oxidative stress 20719 20719 'Serpinb6a' mRNA 2491.03 2343.14 2422.38 100.54 93.06 103.17 111.3 107.45 105.7 98.92333333 108.15 3150.53 2973.27 2883.38 2418.85 3002.393333 3.05E-05 0.298350905 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0062023///collagen-containing extracellular matrix+++GO:0097180///serine protease inhibitor complex GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity GO:0007605///sensory perception of sound+++GO:0008406///gonad development+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0071470///cellular response to osmotic stress 20720 20720 'Serpine2' mRNA 5710 6158 6057 156.55 166.75 176.35 272.05 296 282.17 166.55 283.4066667 11377 12081 11423 5975 11627 2.12E-50 0.948161089 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031091///platelet alpha granule+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding+++GO:0030414///peptidase inhibitor activity "GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007596///blood coagulation+++GO:0008285///negative regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0010466///negative regulation of peptidase activity+++GO:0010544///negative regulation of platelet activation+++GO:0010757///negative regulation of plasminogen activation+++GO:0010766///negative regulation of sodium ion transport+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010955///negative regulation of protein processing+++GO:0010976///positive regulation of neuron projection development+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0021683///cerebellar granular layer morphogenesis+++GO:0030154///cell differentiation+++GO:0030195///negative regulation of blood coagulation+++GO:0030308///negative regulation of cell growth+++GO:0032940///secretion by cell+++GO:0033363///secretory granule organization+++GO:0042177///negative regulation of protein catabolic process+++GO:0042628///mating plug formation+++GO:0045861///negative regulation of proteolysis+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048505///regulation of timing of cell differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0050974///detection of mechanical stimulus involved in sensory perception+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0060384///innervation+++GO:0061108///seminal vesicle epithelium development+++GO:0061110///dense core granule biogenesis+++GO:0090331///negative regulation of platelet aggregation" 207209 207209 'Ccdc154' mRNA 0 1 4.07 0 0.02 0.18 0.08 0 0.04 0.066666667 0.04 4 0 1 1.69 1.666666667 0.984375857 -0.075475992 GO:0005575///cellular_component+++GO:0005768///endosome+++GO:0005769///early endosome GO:0003674///molecular_function GO:0008150///biological_process+++GO:0035630///bone mineralization involved in bone maturation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0044691///tooth eruption+++GO:0045453///bone resorption 207212 207212 'Arhgef17' mRNA 1730 1879 1372 8.83 9.43 7.43 5.31 4.04 4.43 8.563333333 4.593333333 1199 890 969 1660.333333 1019.333333 7.66E-11 -0.712427676 GO:0005085///guanyl-nucleotide exchange factor activity GO:0030036///actin cytoskeleton organization+++GO:0050790///regulation of catalytic activity 207214 207214 'Larp4' mRNA 518 426 562 4.19 3.38 4.79 7.66 6.11 7.93 4.12 7.233333333 1093 851 1093 502 1012.333333 2.14E-13 0.992905655 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:0022627///cytosolic small ribosomal subunit GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding GO:0006412///translation+++GO:0007010///cytoskeleton organization+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0022604///regulation of cell morphogenesis+++GO:0045727///positive regulation of translation 207215 207215 'Fbxo40' mRNA 3 1 0 0.03 0.01 0 0.05 0.08 0.06 0.013333333 0.063333333 6 9 6 1.333333333 7 0.102128716 2.401297904 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0042692///muscle cell differentiation 207227 207227 'Stxbp5l' mRNA 111 96 129 0.48 0.41 0.59 0.04 0.02 0.03 0.493333333 0.03 11 4 9 112 8 4.69E-19 -3.828607793 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0031594///neuromuscular junction+++GO:0098992///neuronal dense core vesicle GO:0005096///GTPase activator activity+++GO:0019905///syntaxin binding+++GO:0045159///myosin II binding GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0042593///glucose homeostasis+++GO:0046676///negative regulation of insulin secretion+++GO:0050708///regulation of protein secretion+++GO:0050714///positive regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:2000300///regulation of synaptic vesicle exocytosis 20723 20723 'Serpinb9' mRNA 439 541 458 8.73 10.81 10.21 13.57 12.81 11.13 9.916666667 12.50333333 755 703 619 479.3333333 692.3333333 2.70E-05 0.51922893 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0001913///T cell mediated cytotoxicity+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033668///negative regulation by symbiont of host apoptotic process+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0070233///negative regulation of T cell apoptotic process 20724 20724 'Serpinb5' mRNA 12 8 10 0.26 0.17 0.23 1.54 1.48 1.42 0.22 1.48 82 77 74 10 77.66666667 5.33E-12 2.944642512 04115///p53 signaling pathway+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004867///serine-type endopeptidase inhibitor activity GO:0002009///morphogenesis of an epithelium+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030198///extracellular matrix organization+++GO:0050678///regulation of epithelial cell proliferation+++GO:0060512///prostate gland morphogenesis 20725 20725 'Serpinb8' mRNA 30 47 17 0.58 0.99 0.32 6.15 5.65 6.76 0.63 6.186666667 316 296 321 31.33333333 311 4.50E-40 3.308434384 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0090136///epithelial cell-cell adhesion 207259 207259 'Zbtb7c' mRNA 57 42 60 0.65 0.48 0.74 0.46 0.4 0.53 0.623333333 0.463333333 44 38 51 53 44.33333333 0.540580091 -0.275427362 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding 20726 20726 'Serpinb9d' mRNA 2 0 3 0.06 0 0.1 0 0.05 0 0.053333333 0.016666667 0 2 0 1.666666667 0.666666667 0.686236216 -1.34708957 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010951///negative regulation of endopeptidase activity+++GO:0033668///negative regulation by symbiont of host apoptotic process+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 207278 207278 'Fchsd2' mRNA 576 596 544 7.15 7.26 7.15 8.13 8.17 8.89 7.186666667 8.396666667 755 740 799 572 764.6666667 9.11E-05 0.408196845 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0120043///stereocilium shaft "GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0006897///endocytosis+++GO:0007274///neuromuscular synaptic transmission+++GO:0015031///protein transport+++GO:0030833///regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0044803///multi-organism membrane organization+++GO:0072583///clathrin-dependent endocytosis+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 20728 20728 'Spic' mRNA 2 2 1 0.1 0.09 0.05 0.08 0.39 0.3 0.08 0.256666667 2 9 7 1.666666667 6 0.212830255 1.855586933 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001824///blastocyst development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 20729 20729 'Spin1' mRNA 2166.97 2382.19 2137.79 19.86 21.21 20.16 18.77 17.44 18.95 20.41 18.38666667 2162.6 1927.41 2120.11 2228.983333 2070.04 0.141670717 -0.118169764 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031965///nuclear membrane GO:0003677///DNA binding+++GO:0035064///methylated histone binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007143///female meiotic nuclear division+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0009303///rRNA transcription+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051321///meiotic cell cycle" 207304 207304 'Hectd1' mRNA 2427.81 2433.13 2237.91 14.16 13.97 13.84 12.49 10.59 11.61 13.99 11.56333333 2467.68 2046.15 2223.98 2366.283333 2245.936667 0.308493149 -0.087525662 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001779///natural killer cell differentiation+++GO:0001843///neural tube closure+++GO:0001892///embryonic placenta development+++GO:0003170///heart valve development+++GO:0003281///ventricular septum development+++GO:0016567///protein ubiquitination+++GO:0035904///aorta development+++GO:0048856///anatomical structure development+++GO:0051865///protein autoubiquitination+++GO:0060707///trophoblast giant cell differentiation+++GO:0060708///spongiotrophoblast differentiation+++GO:0070534///protein K63-linked ubiquitination+++GO:1903077///negative regulation of protein localization to plasma membrane 20731 20731 'Spink4' mRNA 1 0 0 0.26 0 0 0 0 0 0.086666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 20732 20732 'Spint1' mRNA 2432 2483 2435 58.98 59.33 62.85 52.85 53.14 52.65 60.38666667 52.88 2485 2458 2409 2450 2450.666667 0.892638561 -0.0119098 05202///Transcriptional misregulation in cancer+++05215///Prostate cancer GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0001843///neural tube closure+++GO:0001892///embryonic placenta development+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030198///extracellular matrix organization+++GO:0045687///positive regulation of glial cell differentiation+++GO:0046718///viral entry into host cell+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060674///placenta blood vessel development+++GO:0071773///cellular response to BMP stimulus+++GO:2000178///negative regulation of neural precursor cell proliferation 20733 20733 'Spint2' mRNA 16866 16772 16149 781.06 766.78 793.21 617.18 607.58 609.09 780.35 611.2833333 15262 14664 14573 16595.66667 14833 4.38E-04 -0.174029805 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0001843///neural tube closure+++GO:0007163///establishment or maintenance of cell polarity+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0060672///epithelial cell morphogenesis involved in placental branching+++GO:0071711///basement membrane organization+++GO:0071773///cellular response to BMP stimulus+++GO:2000146///negative regulation of cell motility+++GO:2000178///negative regulation of neural precursor cell proliferation 207352 207352 'Sec23ip' mRNA 905 749 958.03 10.7 8.99 11.98 15.38 14.43 15.54 10.55666667 15.11666667 1495.38 1371.05 1462.47 870.6766667 1442.966667 1.11E-10 0.711287501 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site+++GO:0097038///perinuclear endoplasmic reticulum GO:0004620///phospholipase activity+++GO:0046872///metal ion binding GO:0001675///acrosome assembly+++GO:0007286///spermatid development+++GO:0007338///single fertilization 20737 20737 'Spn' mRNA 7 1 2 0.24 0.04 0.04 0.65 0.6 0.78 0.106666667 0.676666667 40 28 37 3.333333333 35 3.46E-06 3.381767629 04514///Cell adhesion molecules GO:0001931///uropod+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body+++GO:0032154///cleavage furrow+++GO:0042995///cell projection GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding GO:0001562///response to protozoan+++GO:0001808///negative regulation of type IV hypersensitivity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0007162///negative regulation of cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0010468///regulation of gene expression+++GO:0031295///T cell costimulation+++GO:0032609///interferon-gamma production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0042742///defense response to bacterium+++GO:0045060///negative thymic T cell selection+++GO:0050688///regulation of defense response to virus+++GO:0050776///regulation of immune response+++GO:0050852///T cell receptor signaling pathway+++GO:0050863///regulation of T cell activation+++GO:0050868///negative regulation of T cell activation+++GO:0050901///leukocyte tethering or rolling+++GO:0071594///thymocyte aggregation+++GO:0097190///apoptotic signaling pathway+++GO:2000404///regulation of T cell migration+++GO:2000406///positive regulation of T cell migration 207375 207375 'Fam120c' mRNA 642 620 469 4.64 4.48 3.51 2.99 2.55 2.81 4.21 2.783333333 484 414 440 577 446 0.004603202 -0.378945286 GO:0005634///nucleus GO:0008150///biological_process 20739 20739 'Spta1' mRNA 0 1 0 0 0.01 0 0 0.02 0.01 0.003333333 0.01 0 3 1 0.333333333 1.333333333 0.606866237 1.902873344 04210///Apoptosis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0008091///spectrin+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014731///spectrin-associated cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0032437///cuticular plate+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0002260///lymphocyte homeostasis+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0007009///plasma membrane organization+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0030097///hemopoiesis+++GO:0032092///positive regulation of protein binding+++GO:0042102///positive regulation of T cell proliferation+++GO:0051693///actin filament capping 207393 207393 'Elfn2' mRNA 138 91 44 0.94 0.63 0.33 0.02 0.06 0.06 0.633333333 0.046666667 4 9 9 91 7.333333333 2.04E-12 -3.62501166 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0004864///protein phosphatase inhibitor activity GO:0010923///negative regulation of phosphatase activity+++GO:0043086///negative regulation of catalytic activity 20740 20740 'Sptan1' mRNA 2982 3063 2630 19.72 19.92 18.45 16.35 16.47 16.86 19.36333333 16.56 2850 2809 2851 2891.666667 2836.666667 0.658822443 -0.036948585 04210///Apoptosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005916///fascia adherens+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0032437///cuticular plate+++GO:0032991///protein-containing complex+++GO:0033010///paranodal junction+++GO:0033270///paranode region of axon+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0019905///syntaxin binding+++GO:0030507///spectrin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0030036///actin cytoskeleton organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0051693///actin filament capping 20741 20741 'Sptb' mRNA 779 816 711 3.92 4.04 3.8 1.45 1.06 1.3 3.92 1.27 332 237 288 768.6666667 285.6666667 2.44E-30 -1.440117248 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0008091///spectrin+++GO:0009986///cell surface+++GO:0014731///spectrin-associated cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0030506///ankyrin binding+++GO:0051015///actin filament binding GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0007009///plasma membrane organization+++GO:0007010///cytoskeleton organization+++GO:0030036///actin cytoskeleton organization+++GO:0030097///hemopoiesis+++GO:0051693///actin filament capping 20742 20742 'Sptbn1' mRNA 7967 7824 6601 48.94 47.42 43.28 35.89 33.31 35.86 46.54666667 35.02 6641 6055 6468 7464 6388 1.53E-04 -0.233589478 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008091///spectrin+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030673///axolemma+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0031430///M band+++GO:0032437///cuticular plate+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0030506///ankyrin binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0051020///GTPase binding GO:0000281///mitotic cytokinesis+++GO:0007009///plasma membrane organization+++GO:0007010///cytoskeleton organization+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0032743///positive regulation of interleukin-2 production+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0051693///actin filament capping+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0071709///membrane assembly+++GO:0072659///protein localization to plasma membrane+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903078///positive regulation of protein localization to plasma membrane 207425 207425 'Wdr11' mRNA 1150 1167 1128 13.56 13.54 14.11 10.91 10.07 10.29 13.73666667 10.42333333 1064 959 972 1148.333333 998.3333333 0.018392391 -0.214605905 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0007507///heart development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035264///multicellular organism growth+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:0099041///vesicle tethering to Golgi 20743 20743 'Sptbn2' mRNA 452 443 430 2.4 2.31 2.42 0.97 1.02 0.93 2.376666667 0.973333333 211 217 196 441.6666667 208 4.53E-15 -1.097902489 05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000139///Golgi membrane+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0008091///spectrin+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0033010///paranodal junction+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099189///postsynaptic spectrin-associated cytoskeleton GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005543///phospholipid binding+++GO:0051015///actin filament binding+++GO:0098918///structural constituent of synapse GO:0007010///cytoskeleton organization+++GO:0007416///synapse assembly+++GO:0016079///synaptic vesicle exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0021692///cerebellar Purkinje cell layer morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030534///adult behavior+++GO:0035264///multicellular organism growth+++GO:0051693///actin filament capping+++GO:0099173///postsynapse organization 20744 20744 'Strbp' mRNA 7214.36 7480.13 7054.09 26.6 29.03 30.23 11.88 9.23 11.44 28.62 10.85 3246.73 2590.03 2903.71 7249.526667 2913.49 1.04E-83 -1.328878753 GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding GO:0006928///movement of cell or subcellular component+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007638///mechanosensory behavior+++GO:0030154///cell differentiation 20745 20745 'Spock1' mRNA 3866 3724 3390 50.18 48.42 44.82 5.83 6.64 6.38 47.80666667 6.283333333 500 521 464 3660 495 0 -2.89625312 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016528///sarcoplasm+++GO:0031594///neuromuscular junction+++GO:0033268///node of Ranvier GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0008191///metalloendopeptidase inhibitor activity GO:0001764///neuron migration+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010977///negative regulation of neuron projection development+++GO:0021953///central nervous system neuron differentiation+++GO:0022008///neurogenesis 20747 20747 'Spop' mRNA 4882 4972 4909 87.08 87.22 92.94 84.3 86.26 82.28 89.08 84.28 5440 5432 5139 4921 5337 0.12091148 0.104556057 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0016607///nuclear speck+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0045171///intercellular bridge GO:0001085///RNA polymerase II transcription factor binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016422///mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0099122///RNA polymerase II C-terminal domain binding+++GO:1904047///S-adenosyl-L-methionine binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0017148///negative regulation of translation+++GO:0030162///regulation of proteolysis+++GO:0032259///methylation+++GO:0042593///glucose homeostasis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045727///positive regulation of translation+++GO:0080009///mRNA methylation+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process 207474 207474 'Kctd12b' mRNA 229 264 251 2.55 2.89 2.96 2.15 1.84 2.12 2.8 2.036666667 222 186 212 248 206.6666667 0.140806445 -0.276572702 GO:0043235///receptor complex GO:0042802///identical protein binding GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0051260///protein homooligomerization 207495 207495 'Baiap2l2' mRNA 85 65 39 2.3 1.73 1.1 0.29 0.1 0.36 1.71 0.25 9 4 13 63 8.666666667 3.05E-08 -2.86369747 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044291///cell-cell contact zone+++GO:0071439///clathrin complex GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0007009///plasma membrane organization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051017///actin filament bundle assembly+++GO:0051764///actin crosslink formation+++GO:0061024///membrane organization+++GO:2000251///positive regulation of actin cytoskeleton reorganization 20750 20750 'Spp1' mRNA 143594 149008 140611 6000 6142.18 6232.43 10441.91 10856.17 10512.32 6124.87 10603.46667 286645 290750 279157 144404.3333 285517.3333 2.84E-96 0.972053015 04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04620///Toll-like receptor signaling pathway+++04929///GnRH secretion+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0005125///cytokine activity+++GO:0005178///integrin binding+++GO:0050840///extracellular matrix binding "GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0006710///androgen catabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0006883///cellular sodium ion homeostasis+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0010033///response to organic substance+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030593///neutrophil chemotaxis+++GO:0030643///cellular phosphate ion homeostasis+++GO:0030644///cellular chloride ion homeostasis+++GO:0031214///biomineral tissue development+++GO:0033280///response to vitamin D+++GO:0034418///urate biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045780///positive regulation of bone resorption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048545///response to steroid hormone+++GO:0071394///cellular response to testosterone stimulus+++GO:0071498///cellular response to fluid shear stress+++GO:0072044///collecting duct development+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000866///positive regulation of estradiol secretion" 20751 20751 'Spr' mRNA 935 991 733 46.64 48.82 38.8 54.46 48.76 51.56 44.75333333 51.59333333 1253 1094 1147 886.3333333 1164.666667 1.70E-04 0.38647969 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004757///sepiapterin reductase activity+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity GO:0006558///L-phenylalanine metabolic process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0010033///response to organic substance+++GO:0019889///pteridine metabolic process+++GO:0040014///regulation of multicellular organism growth+++GO:0042415///norepinephrine metabolic process+++GO:0042417///dopamine metabolic process+++GO:0042428///serotonin metabolic process+++GO:0046146///tetrahydrobiopterin metabolic process+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050882///voluntary musculoskeletal movement 207521 207521 'Dtx4' mRNA 347 382 414 3.8 4.05 4.82 10.91 10.35 10.16 4.223333333 10.47333333 1147 1072 1042 381 1087 1.34E-41 1.497331869 04330///Notch signaling pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination 20753 20753 'Sprr1a' mRNA 8 17 18 0.69 1.46 1.65 57.27 52.29 56.27 1.266666667 55.27666667 757 673 718 14.33333333 716 5.32E-108 5.629698793 GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0071944///cell periphery GO:0030280///structural constituent of epidermis GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization 20755 20755 'Sprr2a1' mRNA 0.5 0 4.5 0.01 0 0.07 0.06 0.09 0.08 0.026666667 0.076666667 4.5 6.5 6 1.666666667 5.666666667 0.268697535 1.944043279 GO:0001533///cornified envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005200///structural constituent of cytoskeleton GO:0008360///regulation of cell shape+++GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 20756 20756 'Sprr2b' mRNA 1 0 0 0.1 0 0 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0001533///cornified envelope+++GO:0005737///cytoplasm GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 207565 207565 'Camkk2' mRNA 285 340 259 4.33 5.31 3.71 5.83 5.68 5.41 4.45 5.64 477 448 448 294.6666667 457.6666667 5.02E-06 0.626606849 04140///Autophagy - animal+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04936///Alcoholic liver disease+++05034///Alcoholism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0046777///protein autophosphorylation+++GO:0061762///CAMKK-AMPK signaling cascade 20759 20759 'Sprr2e' mRNA 1 0 0 0.11 0 0 0 0.51 0 0.036666667 0.17 0 5 0 0.333333333 1.666666667 0.544188322 2.229773786 GO:0001533///cornified envelope+++GO:0005737///cytoplasm GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 207592 207592 'Tbc1d16' mRNA 315 321 258 2.37 2.38 2.07 1.56 1.63 1.54 2.273333333 1.576666667 239 242 227 298 236 0.036830757 -0.344486282 GO:0005769///early endosome+++GO:0005829///cytosol GO:0005096///GTPase activator activity GO:0001919///regulation of receptor recycling+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 207596 207596 'Thsd4' mRNA 2212 2244 1730 13.35 13.41 11.79 6.2 5.25 5.46 12.85 5.636666667 1076 929 945 2062 983.3333333 3.42E-33 -1.076177103 04350///TGF-beta signaling pathway GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0002064///epithelial cell development+++GO:0006915///apoptotic process+++GO:0030198///extracellular matrix organization+++GO:0043065///positive regulation of apoptotic process+++GO:0048251///elastic fiber assembly 20760 20760 'Sprr2f' mRNA 1 2 0 0.12 0.25 0 0 0 0 0.123333333 0 0 0 0 1 0 0.616323562 -2.415498512 GO:0001533///cornified envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008544///epidermis development+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032355///response to estradiol 207607 207607 'Ccdc40' mRNA 2083 2184 2291 23.62 24.64 27.32 2.18 1.9 1.8 25.19333333 1.96 197 191 173 2186 187 2.78E-242 -3.56187865 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0001947///heart looping+++GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007368///determination of left/right symmetry+++GO:0030317///flagellated sperm motility+++GO:0030324///lung development+++GO:0035082///axoneme assembly+++GO:0035469///determination of pancreatic left/right asymmetry+++GO:0036159///inner dynein arm assembly+++GO:0044458///motile cilium assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0061512///protein localization to cilium+++GO:0070286///axonemal dynein complex assembly+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0071910///determination of liver left/right asymmetry 207615 207615 'Wdr37' mRNA 694 710 610 8.67 8.81 8.25 8.35 7.46 8.35 8.576666667 8.053333333 742 659 728 671.3333333 709.6666667 0.594522269 0.069963065 "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030687///preribosome, large subunit precursor" GO:0003674///molecular_function 207618 207618 'Zfp804b' mRNA 2 2 0 0.03 0.03 0 0 0.02 0 0.02 0.006666667 0 2 0 1.333333333 0.666666667 0.797199703 -0.959602344 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 207667 207667 'Skor1' mRNA 537 516 276 7.92 7.41 4.27 0.42 0.32 0.38 6.533333333 0.373333333 32 24 30 443 28.66666667 1.37E-52 -3.949621636 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0030425///dendrite+++GO:0043025///neuronal cell body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated" 20768 20768 'Sephs2' mRNA 1176 1251 1170 30.42 31.87 32.11 33.32 35.69 32.26 31.46666667 33.75666667 1481 1549 1388 1199 1472.666667 0.001025638 0.285475507 00450///Selenocompound metabolism GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0004756///selenide, water dikinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding" GO:0001887///selenium compound metabolic process+++GO:0016260///selenocysteine biosynthetic process+++GO:0016310///phosphorylation 207683 207683 'Igsf11' mRNA 668 662 643 10.66 10.43 10.88 6.72 7.49 7.37 10.65666667 7.193333333 485 528 515 657.6666667 509.3333333 8.65E-04 -0.379684942 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0060076///excitatory synapse GO:0035255///ionotropic glutamate receptor binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0040008///regulation of growth+++GO:0045185///maintenance of protein location+++GO:0048167///regulation of synaptic plasticity+++GO:0061885///positive regulation of mini excitatory postsynaptic potential+++GO:1900273///positive regulation of long-term synaptic potentiation 207686 207686 'Cfap69' mRNA 1219 1209 1281 16.87 16.24 19.13 1.73 1.37 1.5 17.41333333 1.533333333 134 122 116 1236.333333 124 1.55E-156 -3.332247201 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097225///sperm midpiece+++GO:0097730///non-motile cilium+++GO:1990718///axonemal central pair projection GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0007608///sensory perception of smell+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0042048///olfactory behavior+++GO:0050896///response to stimulus+++GO:1902093///positive regulation of flagellated sperm motility+++GO:1905516///positive regulation of fertilization+++GO:1990834///response to odorant 207704 207704 'Gtpbp10' mRNA 333 326 338 6.14 5.91 6.6 5.46 5.36 5.03 6.216666667 5.283333333 341 327 305 332.3333333 324.3333333 0.808596247 -0.048512686 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008150///biological_process+++GO:0042254///ribosome biogenesis 207728 207728 'Pde2a' mRNA 236 295 282 3.13 3.82 3.96 6.98 7.14 6.78 3.636666667 6.966666667 607 607 571 271 595 4.02E-17 1.121747274 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04740///Olfactory transduction+++04925///Aldosterone synthesis and secretion+++05032///Morphine addiction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane+++GO:0097457///hippocampal mossy fiber "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004118///cGMP-stimulated cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0030552///cAMP binding+++GO:0030553///cGMP binding+++GO:0030911///TPR domain binding+++GO:0036004///GAF domain binding+++GO:0042301///phosphate ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003170///heart valve development+++GO:0003279///cardiac septum development+++GO:0003281///ventricular septum development+++GO:0007165///signal transduction+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0010749///regulation of nitric oxide mediated signal transduction+++GO:0010752///regulation of cGMP-mediated signaling+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0010821///regulation of mitochondrion organization+++GO:0019933///cAMP-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0035904///aorta development+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0043116///negative regulation of vascular permeability+++GO:0043117///positive regulation of vascular permeability+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0046069///cGMP catabolic process+++GO:0050729///positive regulation of inflammatory response+++GO:0060548///negative regulation of cell death+++GO:0060976///coronary vasculature development+++GO:0061028///establishment of endothelial barrier+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071320///cellular response to cAMP+++GO:0071321///cellular response to cGMP+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:1904613///cellular response to 2,3,7,8-tetrachlorodibenzodioxine" 20773 20773 'Sptlc2' mRNA 1428 1612 1499 11.25 12.49 12.53 20.71 19.74 19.4 12.09 19.95 3026 2819 2746 1513 2863.666667 1.93E-35 0.907990969 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex "GO:0003824///catalytic activity+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding" GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0009058///biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0060612///adipose tissue development+++GO:1904504///positive regulation of lipophagy 207740 207740 'Ubald1' mRNA 1053 1146 961 38.06 40.44 37.74 31.24 30.78 28.67 38.74666667 30.23 966 895 864 1053.333333 908.3333333 0.019769838 -0.223605539 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 207742 207742 'Rnf43' mRNA 824 818 779 10.39 10.04 10.31 4.9 4.72 4.7 10.24666667 4.773333333 452 421 416 807 429.6666667 6.61E-19 -0.921214161 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0038018///Wnt receptor catabolic process+++GO:0072089///stem cell proliferation 20775 20775 'Sqle' mRNA 2980 2987 3065 59.95 59.15 65.41 23.21 22.24 23.14 61.50333333 22.86333333 1327 1242 1281 3010.666667 1283.333333 7.81E-66 -1.243951934 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004497///monooxygenase activity+++GO:0004506///squalene monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding GO:0006725///cellular aromatic compound metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010033///response to organic substance+++GO:0016126///sterol biosynthetic process+++GO:0042127///regulation of cell proliferation+++GO:0140042///lipid droplet formation 20776 20776 'Tmie' mRNA 1810 1831 1593 51.07 51.35 49.52 12.44 11.75 11.98 50.64666667 12.05666667 588 519 520 1744.666667 542.3333333 1.03E-87 -1.696083492 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007605///sensory perception of sound+++GO:0042472///inner ear morphogenesis 207777 207777 'Tspoap1' mRNA 461 540 521 3.87 4.48 4.87 1.07 0.91 1.14 4.406666667 1.04 149 115 146 507.3333333 136.6666667 5.31E-34 -1.906720386 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0044305///calyx of Held+++GO:0098978///glutamatergic synapse GO:0030156///benzodiazepine receptor binding+++GO:0099626///voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels GO:0007274///neuromuscular synaptic transmission+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration 20778 20778 'Scarb1' mRNA 1018 1051 1077 23.47 23.99 26.61 28.32 26.84 29.39 24.69 28.18333333 1443 1334 1450 1048.666667 1409 3.02E-06 0.412399939 04145///Phagosome+++04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++04975///Fat digestion and absorption+++04976///Bile secretion+++04977///Vitamin digestion and absorption+++04979///Cholesterol metabolism+++05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031528///microvillus membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001530///lipopolysaccharide binding+++GO:0001540///amyloid-beta binding+++GO:0001786///phosphatidylserine binding+++GO:0001875///lipopolysaccharide receptor activity+++GO:0005044///scavenger receptor activity+++GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0034185///apolipoprotein binding+++GO:0034186///apolipoprotein A-I binding+++GO:0042802///identical protein binding+++GO:0070506///high-density lipoprotein particle receptor activity "GO:0001935///endothelial cell proliferation+++GO:0006702///androgen biosynthetic process+++GO:0006707///cholesterol catabolic process+++GO:0006869///lipid transport+++GO:0006910///phagocytosis, recognition+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010886///positive regulation of cholesterol storage+++GO:0010899///regulation of phosphatidylcholine catabolic process+++GO:0015914///phospholipid transport+++GO:0015920///lipopolysaccharide transport+++GO:0030301///cholesterol transport+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032497///detection of lipopolysaccharide+++GO:0033344///cholesterol efflux+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034381///plasma lipoprotein particle clearance+++GO:0034383///low-density lipoprotein particle clearance+++GO:0034384///high-density lipoprotein particle clearance+++GO:0035461///vitamin transmembrane transport+++GO:0042632///cholesterol homeostasis+++GO:0043534///blood vessel endothelial cell migration+++GO:0043654///recognition of apoptotic cell+++GO:0043691///reverse cholesterol transport+++GO:0044406///adhesion of symbiont to host+++GO:0050764///regulation of phagocytosis+++GO:0050892///intestinal absorption+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0070328///triglyceride homeostasis+++GO:0070508///cholesterol import" 207781 207781 'C2cd2' mRNA 249.51 220 248.82 1.98 1.69 2.07 2.36 2.16 2.21 1.913333333 2.243333333 340.08 306.03 313.27 239.4433333 319.7933333 0.012877857 0.404978412 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 207785 207785 'Csrnp2' mRNA 313 378 195 4.05 4.83 2.67 2.63 3.14 2.83 3.85 2.866666667 236 273 242 295.3333333 250.3333333 0.308116072 -0.236949608 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019902///phosphatase binding+++GO:0043565///sequence-specific DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II 20779 20779 'Src' mRNA 462 458 222 6.5 6.35 3.33 4.69 4.29 5.14 5.393333333 4.706666667 381 340 405 380.6666667 375.3333333 0.948628687 -0.018173913 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04137///Mitophagy - animal+++04144///Endocytosis+++04360///Axon guidance+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04540///Gap junction+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04625///C-type lectin receptor signaling pathway+++04727///GABAergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++05100///Bacterial invasion of epithelial cells+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05135///Yersinia infection+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05219///Bladder cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis "GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032587///ruffle membrane+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005080///protein kinase C binding+++GO:0005102///signaling receptor binding+++GO:0005158///insulin receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016004///phospholipase activator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0020037///heme binding+++GO:0030331///estrogen receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042169///SH2 domain binding+++GO:0043274///phospholipase binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046875///ephrin receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0051219///phosphoprotein binding+++GO:0070700///BMP receptor binding+++GO:0070851///growth factor receptor binding+++GO:0071253///connexin binding+++GO:0097110///scaffold protein binding "GO:0001545///primary ovarian follicle growth+++GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008283///cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009615///response to virus+++GO:0010447///response to acidic pH+++GO:0010628///positive regulation of gene expression+++GO:0010632///regulation of epithelial cell migration+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010641///positive regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010954///positive regulation of protein processing+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0022407///regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0031333///negative regulation of protein complex assembly+++GO:0031648///protein destabilization+++GO:0031667///response to nutrient levels+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032148///activation of protein kinase B activity+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032869///cellular response to insulin stimulus+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034332///adherens junction organization+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0034614///cellular response to reactive oxygen species+++GO:0035306///positive regulation of dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0036035///osteoclast development+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042476///odontogenesis+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043149///stress fiber assembly+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043393///regulation of protein binding+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045056///transcytosis+++GO:0045087///innate immune response+++GO:0045453///bone resorption+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045785///positive regulation of cell adhesion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0048041///focal adhesion assembly+++GO:0048477///oogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050847///progesterone receptor signaling pathway+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051222///positive regulation of protein transport+++GO:0051385///response to mineralocorticoid+++GO:0051602///response to electrical stimulus+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051902///negative regulation of mitochondrial depolarization+++GO:0051974///negative regulation of telomerase activity+++GO:0060065///uterus development+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060491///regulation of cell projection assembly+++GO:0060576///intestinal epithelial cell development+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070542///response to fatty acid+++GO:0070555///response to interleukin-1+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071393///cellular response to progesterone stimulus+++GO:0071398///cellular response to fatty acid+++GO:0071456///cellular response to hypoxia+++GO:0071498///cellular response to fluid shear stress+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071803///positive regulation of podosome assembly+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0086098///angiotensin-activated signaling pathway involved in heart process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902533///positive regulation of intracellular signal transduction+++GO:2000386///positive regulation of ovarian follicle development+++GO:2000394///positive regulation of lamellipodium morphogenesis+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:2000641///regulation of early endosome to late endosome transport+++GO:2000811///negative regulation of anoikis+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:2001286///regulation of caveolin-mediated endocytosis" 207792 207792 'BC034090' mRNA 217.04 185 185.03 2.55 2.13 2.45 1.76 2 1.87 2.376666667 1.876666667 164 190 177.01 195.69 177.0033333 0.502500339 -0.154512767 GO:0005634///nucleus+++GO:0005938///cell cortex+++GO:0016324///apical plasma membrane GO:0005080///protein kinase C binding GO:0007098///centrosome cycle+++GO:0007163///establishment or maintenance of cell polarity+++GO:0060341///regulation of cellular localization 207798 207798 'Gramd1c' mRNA 1182 1282 1347 17.53 18.78 21.25 4.72 3.91 3.57 19.18666667 4.066666667 363 290 266 1270.333333 306.3333333 3.86E-65 -2.068763478 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0071397///cellular response to cholesterol+++GO:0120009///intermembrane lipid transfer 207806 207806 'Usf3' mRNA 451 481 439 1.86 1.95 1.92 1.94 1.63 1.86 1.91 1.81 542 444 503 457 496.3333333 0.476017462 0.106729606 GO:0046983///protein dimerization activity GO:0010719///negative regulation of epithelial to mesenchymal transition 207818 207818 'Smagp' mRNA 91 106 70 5.56 6.39 4.58 14.88 14.89 14.15 5.51 14.64 280 270 255 89 268.3333333 5.75E-16 1.585610877 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle 207819 207819 'Bnip5' mRNA 17.13 10.58 12 0.19 0.12 0.15 0.24 0.3 0.2 0.153333333 0.246666667 24.43 28.99 19.02 13.23666667 24.14666667 0.185733738 0.85389591 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 207839 207839 'Galnt6' mRNA 25 22 19 0.23 0.2 0.19 4.08 3.72 3.68 0.206666667 3.826666667 504 448 440 22 464 4.17E-80 4.387524722 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation 207854 207854 'Fmr1nb' mRNA 1 0 2 0.1 0 0.21 0 0.09 0 0.103333333 0.03 0 1 0 1 0.333333333 0.715918166 -1.529809401 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 20787 20787 'Srebf1' mRNA 12079 12197 11086 151.33 150.36 147.36 82.58 84.88 76.86 149.6833333 81.44 7597 7632 6849 11787.33333 7359.333333 1.84E-34 -0.690034897 04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0032810///sterol response element binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003062///regulation of heart rate by chemical signal+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0007568///aging+++GO:0007623///circadian rhythm+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0008610///lipid biosynthetic process+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010876///lipid localization+++GO:0010883///regulation of lipid storage+++GO:0019217///regulation of fatty acid metabolic process+++GO:0030324///lung development+++GO:0031065///positive regulation of histone deacetylation+++GO:0031647///regulation of protein stability+++GO:0032094///response to food+++GO:0032526///response to retinoic acid+++GO:0032570///response to progesterone+++GO:0032933///SREBP signaling pathway+++GO:0033762///response to glucagon+++GO:0042493///response to drug+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0045089///positive regulation of innate immune response+++GO:0045444///fat cell differentiation+++GO:0045471///response to ethanol+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0050796///regulation of insulin secretion+++GO:0051591///response to cAMP+++GO:0071398///cellular response to fatty acid+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903214///regulation of protein targeting to mitochondrion" 20788 20788 'Srebf2' mRNA 12152 12670 9918 137.23 140.68 118.49 43.2 44.78 44.32 132.1333333 44.1 4416 4427 4372 11580 4405 1.04E-106 -1.401205007 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0032937///SREBP-SCAP-Insig complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008593///regulation of Notch signaling pathway+++GO:0009267///cellular response to starvation+++GO:0009725///response to hormone+++GO:0010886///positive regulation of cholesterol storage+++GO:0032933///SREBP signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0090370///negative regulation of cholesterol efflux+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 207911 207911 'Mchr1' mRNA 23 16 18 0.59 0.41 0.49 1.46 0.8 0.65 0.496666667 0.97 65 35 28 19 42.66666667 0.025743667 1.148537034 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0004930///G protein-coupled receptor activity+++GO:0005102///signaling receptor binding+++GO:0008022///protein C-terminus binding+++GO:0030273///melanin-concentrating hormone receptor activity+++GO:0042277///peptide binding+++GO:0042562///hormone binding+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0051928///positive regulation of calcium ion transport+++GO:0060259///regulation of feeding behavior 207920 207920 'Esrp1' mRNA 784 838 670 11.26 11.7 10.17 8.54 7.44 8.87 11.04333333 8.283333333 690 586 685 764 653.6666667 0.043747496 -0.234172035 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0042669///regulation of inner ear auditory receptor cell fate specification+++GO:0043484///regulation of RNA splicing+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis" 207921 207921 'Fam228b' mRNA 30 37.74 33.49 0.97 1.11 1.36 0.84 0.97 0.63 1.146666667 0.813333333 29.78 36 26.67 33.74333333 30.81666667 0.809491281 -0.146076834 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 207932 207932 'Urb1' mRNA 492 452 433 3.52 3.18 3.29 2.72 2.68 3.11 3.33 2.836666667 438 420 484 459 447.3333333 0.782456974 -0.047933866 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 207952 207952 'Klhl25' mRNA 457 459 399 7.62 7.48 6.94 6.28 6.77 7.05 7.346666667 6.7 434 459 456 438.3333333 449.6666667 0.863090843 0.027894994 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0003674///molecular_function GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 207958 207958 'Alg11' mRNA 861 807 799 9.24 8.55 9.12 7.07 5.33 5.95 8.97 6.116666667 755 551 612 822.3333333 639.3333333 0.001828274 -0.377651694 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004377///GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0097502///mannosylation 207965 207965 'Vcpkmt' mRNA 447 473 420 10.81 11.54 10.83 10.85 11.21 11.09 11.06 11.05 469 458 456 446.6666667 461 0.840575106 0.035133196 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0051117///ATPase binding GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation+++GO:0032780///negative regulation of ATPase activity 208043 208043 'Setd1b' mRNA 647 589 457 3.85 3.45 2.9 2.29 1.95 2.37 3.4 2.203333333 442 367 445 564.3333333 418 0.00181135 -0.44043375 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0035097///histone methyltransferase complex+++GO:0048188///Set1C/COMPASS complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific) GO:0006325///chromatin organization+++GO:0032259///methylation+++GO:0044648///histone H3-K4 dimethylation+++GO:0051568///histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0097692///histone H3-K4 monomethylation 20807 20807 'Srf' mRNA 185 151 212 2.66 2.13 3.2 2.34 2.19 2.81 2.663333333 2.446666667 188 175 218 182.6666667 193.6666667 0.824047303 0.06605093 04010///MAPK signaling pathway+++04022///cGMP-PKG signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0010736///serum response element binding+++GO:0031490///chromatin DNA binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070878///primary miRNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0001764///neuron migration+++GO:0001829///trophectodermal cell differentiation+++GO:0001947///heart looping+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002521///leukocyte differentiation+++GO:0003257///positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007015///actin filament organization+++GO:0007160///cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0007507///heart development+++GO:0007616///long-term memory+++GO:0008285///negative regulation of cell proliferation+++GO:0008306///associative learning+++GO:0009725///response to hormone+++GO:0010669///epithelial structure maintenance+++GO:0010735///positive regulation of transcription via serum response element binding+++GO:0021766///hippocampus development+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0030036///actin cytoskeleton organization+++GO:0030038///contractile actin filament bundle assembly+++GO:0030155///regulation of cell adhesion+++GO:0030168///platelet activation+++GO:0030220///platelet formation+++GO:0030336///negative regulation of cell migration+++GO:0030878///thyroid gland development+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0033561///regulation of water loss via skin+++GO:0034097///response to cytokine+++GO:0035855///megakaryocyte development+++GO:0035912///dorsal aorta morphogenesis+++GO:0043149///stress fiber assembly+++GO:0043589///skin morphogenesis+++GO:0045059///positive thymic T cell selection+++GO:0045214///sarcomere organization+++GO:0045597///positive regulation of cell differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046016///positive regulation of transcription by glucose+++GO:0046716///muscle cell cellular homeostasis+++GO:0048538///thymus development+++GO:0048589///developmental growth+++GO:0048821///erythrocyte development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051491///positive regulation of filopodium assembly+++GO:0055003///cardiac myofibril assembly+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060292///long-term synaptic depression+++GO:0060324///face development+++GO:0060347///heart trabecula formation+++GO:0060425///lung morphogenesis+++GO:0060532///bronchus cartilage development+++GO:0060534///trachea cartilage development+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0061029///eyelid development in camera-type eye+++GO:0061145///lung smooth muscle development+++GO:0070830///bicellular tight junction assembly+++GO:0071333///cellular response to glucose stimulus+++GO:0090009///primitive streak formation+++GO:0090136///epithelial cell-cell adhesion+++GO:0090398///cellular senescence+++GO:0098609///cell-cell adhesion+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 208076 208076 'Pknox2' mRNA 1085 1091 1006 16.78 16.5 16.51 7.21 6.87 6.56 16.59666667 6.88 542 500 481 1060.666667 507.6666667 9.99E-30 -1.074415429 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003785///actin monomer binding+++GO:0043565///sequence-specific DNA binding+++GO:0051015///actin filament binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 208080 208080 'Ubap1l' mRNA 74.04 64.63 73 0.5 0.44 0.51 0.52 0.35 0.54 0.483333333 0.47 87.97 67.85 94.23 70.55666667 83.35 0.543755842 0.2178799 GO:0000813///ESCRT I complex GO:0043130///ubiquitin binding GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 208084 208084 'Pif1' mRNA 1 3 1 0.03 0.06 0.02 1.78 1.36 0.83 0.036666667 1.323333333 106 83.03 54 1.666666667 81.01 3.20E-13 5.591257467 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005739///mitochondrion" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0010521///telomerase inhibitor activity+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0033678///5'-3' DNA/RNA helicase activity+++GO:0042162///telomeric DNA binding+++GO:0043139///5'-3' DNA helicase activity+++GO:0051880///G-quadruplex DNA binding GO:0000002///mitochondrial genome maintenance+++GO:0000723///telomere maintenance+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032204///regulation of telomere maintenance+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032508///DNA duplex unwinding+++GO:0051974///negative regulation of telomerase activity 208092 208092 'Chmp6' mRNA 841 803 795 31.59 29.77 31.71 35.03 37.45 35.92 31.02333333 36.13333333 1072 1119 1061 813 1084 1.39E-05 0.403656791 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0031902///late endosome membrane GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0006900///vesicle budding from membrane+++GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0015031///protein transport+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0042176///regulation of protein catabolic process+++GO:0061952///midbody abscission 208098 208098 'Panx3' mRNA 2 7 5 0.04 0.15 0.12 0.56 0.37 0.32 0.103333333 0.416666667 29 19 16 4.666666667 21.33333333 0.005469875 2.176712084 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0015267///channel activity+++GO:0022829///wide pore channel activity+++GO:0055077///gap junction hemi-channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007267///cell-cell signaling+++GO:0032732///positive regulation of interleukin-1 production+++GO:0055085///transmembrane transport 20810 20810 'Srm' mRNA 636 586 400 28.87 26.25 19.26 30.64 48.91 42.88 24.79333333 40.81 775 1207 1049 540.6666667 1010.333333 0.001241411 0.903804855 00270///Cysteine and methionine metabolism+++00330///Arginine and proline metabolism+++00480///Glutathione metabolism GO:0003824///catalytic activity+++GO:0004766///spermidine synthase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0008295///spermidine biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 208104 208104 'Mlxip' mRNA 3257.02 3426 1945 55 57.04 27.99 19.99 33.81 29.06 46.67666667 27.62 1637 2400 2112.01 2876.006667 2049.67 0.111794529 -0.484016954 04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006913///nucleocytoplasmic transport+++GO:0045944///positive regulation of transcription by RNA polymerase II" 20811 20811 'Srms' mRNA 31 24 17 0.68 0.52 0.39 1.78 1.64 1.89 0.53 1.77 94 84.14 96.34 24 91.49333333 3.09E-08 1.9216703 GO:0005737///cytoplasm+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0045087///innate immune response 208111 208111 'Zfp976' mRNA 251.46 256.37 266.59 2.59 2.59 2.94 1.65 1.43 1.6 2.706666667 1.56 181.09 151.66 173.98 258.14 168.91 4.07E-04 -0.628746326 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034605///cellular response to heat" 208117 208117 'Aph1b' mRNA 1486.77 1505.62 1492.02 16 15.77 16.95 11.85 10.38 10.79 16.24 11.00666667 1258.18 1086.01 1124.94 1494.803333 1156.376667 6.67E-06 -0.384032168 04330///Notch signaling pathway+++05010///Alzheimer disease GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0045202///synapse+++GO:0070765///gamma-secretase complex "GO:0030674///protein binding, bridging+++GO:0061133///endopeptidase activator activity" "GO:0001656///metanephros development+++GO:0001963///synaptic transmission, dopaminergic+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007614///short-term memory+++GO:0007626///locomotory behavior+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0034205///amyloid-beta formation+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0060134///prepulse inhibition" 20813 20813 'Srp14' mRNA 3568 3701 3542 308.94 317.7 325.47 336.83 340.96 328.83 317.37 335.54 4452 4388 4196 3603.666667 4345.333333 2.73E-05 0.258020655 03060///Protein export "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0048500///signal recognition particle" GO:0003723///RNA binding+++GO:0008312///7S RNA binding+++GO:0030942///endoplasmic reticulum signal peptide binding GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0045047///protein targeting to ER 208144 208144 'Dhx37' mRNA 615.03 511.68 558.01 7.46 6.08 7.04 4.01 4.04 3.78 6.86 3.943333333 385.72 384.35 361.3 561.5733333 377.1233333 5.70E-06 -0.588459182 GO:0005622///intracellular+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0034511///U3 snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0007420///brain development+++GO:0042254///ribosome biogenesis+++GO:0042255///ribosome assembly+++GO:2000020///positive regulation of male gonad development" 208146 208146 'Yeats2' mRNA 1950.7 1970.97 1934.91 18.97 18.94 20.07 9 8.03 8.1 19.32666667 8.376666667 1077.99 961.55 998.43 1952.193333 1012.656667 1.85E-35 -0.960337142 GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0072686///mitotic spindle GO:0017025///TBP-class protein binding+++GO:0042393///histone binding+++GO:0140030///modification-dependent protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043966///histone H3 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated" 20815 20815 'Srpk1' mRNA 516 540 495 11.23 11.61 11.45 13.68 12.46 13.71 11.43 13.28333333 717 638 696 517 683.6666667 3.49E-04 0.391475016 05168///Herpes simplex virus 1 infection GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000245///spliceosomal complex assembly+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0007059///chromosome segregation+++GO:0008380///RNA splicing+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0045070///positive regulation of viral genome replication+++GO:0045071///negative regulation of viral genome replication+++GO:0050684///regulation of mRNA processing 208151 208151 'Tmem132b' mRNA 0 3 2 0 0.02 0.01 0 0.01 0.01 0.01 0.006666667 0 1 1 1.666666667 0.666666667 0.671660644 -1.324734001 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 208154 208154 'Btla' mRNA 4 10 3 0.07 0.18 0.05 0.48 0.56 0.47 0.1 0.503333333 32 34 31 5.666666667 32.33333333 1.15E-04 2.51246548 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0030889///negative regulation of B cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0046642///negative regulation of alpha-beta T cell proliferation 208158 208158 'Map6d1' mRNA 37 49 31 0.62 0.8 0.55 0.36 0.31 0.42 0.656666667 0.363333333 25 21 28 39 24.66666667 0.170107749 -0.666598741 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005801///cis-Golgi network+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005516///calmodulin binding+++GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0018009///N-terminal peptidyl-L-cysteine N-palmitoylation+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0070507///regulation of microtubule cytoskeleton organization 208164 208164 'Fam180a' mRNA 467 487 404 17.97 18.48 16.49 133.65 128.96 128.27 17.64666667 130.2933333 3990 3757 3705 452.6666667 3817.333333 0 3.066214763 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 208166 208166 'Gm609' mRNA 2.07 1 4 0.09 0.07 0.16 0.25 0.26 0.13 0.106666667 0.213333333 4 4 2 2.356666667 3.333333333 0.809260148 0.48039547 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 20817 20817 'Srpk2' mRNA 2183.45 2108.19 2224.46 24.45 23.62 26.69 18.8 17.95 19.21 24.92 18.65333333 1913.25 1733.08 1877.64 2172.033333 1841.323333 0.001777479 -0.252577817 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0071889///14-3-3 protein binding GO:0000245///spliceosomal complex assembly+++GO:0001525///angiogenesis+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0035063///nuclear speck organization+++GO:0035556///intracellular signal transduction+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045071///negative regulation of viral genome replication+++GO:0045787///positive regulation of cell cycle+++GO:0050684///regulation of mRNA processing 208171 208171 'Tmprss7' mRNA 151 126 133 2.93 2.58 2.8 0.19 0.54 0.32 2.77 0.35 13 33 24 136.6666667 23.33333333 1.18E-14 -2.557622073 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 208177 208177 'Phldb2' mRNA 1244 1225 1146 10.56 10.32 10.21 18.86 17.5 17.66 10.36333333 18.00666667 2491 2225 2269 1205 2328.333333 4.16E-39 0.93844713 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0031252///cell leading edge+++GO:0045111///intermediate filament cytoskeleton+++GO:0045180///basal cortex "GO:0000226///microtubule cytoskeleton organization+++GO:0010470///regulation of gastrulation+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0045184///establishment of protein localization+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis" 20818 20818 'Srprb' mRNA 1755 1926 1933 32.24 34.82 37.67 36.59 34.95 37 34.91 36.18 2292 2138 2244 1871.333333 2224.666667 0.004223474 0.235593835 03060///Protein export GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005785///signal recognition particle receptor complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding GO:0045047///protein targeting to ER 208194 208194 'Exog' mRNA 205 195 213 3.14 3.22 3.62 3.61 3.3 3.47 3.326666667 3.46 248 235 237 204.3333333 240 0.258470549 0.21804577 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006309///apoptotic DNA fragmentation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 208198 208198 'Btbd2' mRNA 520 592 403 11.87 13.31 9.75 9.41 8.28 9.51 11.64333333 9.066666667 475 407 464 505 448.6666667 0.261148742 -0.176830405 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0022008///neurogenesis 20821 20821 'Trim21' mRNA 382 440 508 7.56 8.62 10.67 10.06 9.48 9.68 8.95 9.74 585 538 545 443.3333333 556 0.039397788 0.308985923 05322///Systemic lupus erythematosus GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031410///cytoplasmic vesicle GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032092///positive regulation of protein binding+++GO:0032880///regulation of protein localization+++GO:0032897///negative regulation of viral transcription+++GO:0034341///response to interferon-gamma+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045787///positive regulation of cell cycle+++GO:0045824///negative regulation of innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0090086///negative regulation of protein deubiquitination+++GO:1902187///negative regulation of viral release from host cell" 208211 208211 'Alg1' mRNA 714.41 670.02 634.36 23.29 21.57 22.01 22.59 24.29 25.78 22.29 24.22 791.88 830.09 873.6 672.93 831.8566667 0.005430799 0.29548058 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0004578///chitobiosyldiphosphodolichol beta-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0097502///mannosylation 208213 208213 'Tmem132c' mRNA 556 556 551 5.8 5.71 6.1 2.09 1.76 1.93 5.87 1.926666667 231 190 206 554.3333333 209 1.88E-26 -1.420851858 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0010923///negative regulation of phosphatase activity 20822 20822 'Ro60' mRNA 1825 1912 1852 16.33 17.18 17.11 9.77 9.26 8.65 16.87333333 9.226666667 1441 1240 1277 1863 1319.333333 1.79E-10 -0.511320537 05322///Systemic lupus erythematosus GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding+++GO:0034336///misfolded RNA binding+++GO:0046872///metal ion binding GO:0002520///immune system development+++GO:0007224///smoothened signaling pathway+++GO:0009411///response to UV+++GO:0010468///regulation of gene expression+++GO:0030030///cell projection organization+++GO:0035457///cellular response to interferon-alpha+++GO:0060271///cilium assembly 208228 208228 'Mob3a' mRNA 454 443 478 9.51 9.14 10.63 19.98 19.96 18.27 9.76 19.40333333 1097 1070 971 458.3333333 1046 7.37E-29 1.176459541 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0008150///biological_process 20823 20823 'Ssb' mRNA 2060.26 2068.38 1957.98 56.72 56.08 57.13 68.8 70.36 66.96 56.64333333 68.70666667 2873.95 2870.33 2707.49 2028.873333 2817.256667 2.46E-12 0.462411643 05322///Systemic lupus erythematosus GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000049///tRNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008266///poly(U) RNA binding+++GO:1990825///sequence-specific mRNA binding GO:0001682///tRNA 5'-leader removal+++GO:0006396///RNA processing+++GO:0006409///tRNA export from nucleus+++GO:0008033///tRNA processing+++GO:0042780///tRNA 3'-end processing+++GO:0071045///nuclear histone mRNA catabolic process+++GO:0075522///IRES-dependent viral translational initiation+++GO:1903608///protein localization to cytoplasmic stress granule 20826 20826 'Snu13' mRNA 2596 2731.78 2689.63 125.72 130.61 138.2 113.15 119.17 118.97 131.51 117.0966667 2682 2755.01 2727 2672.47 2721.336667 0.877270766 0.014105147 03008///Ribosome biogenesis in eukaryotes+++03040///Spliceosome GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005690///U4atac snRNP+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0031428///box C/D snoRNP complex+++GO:0032040///small-subunit processome+++GO:0032991///protein-containing complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0030515///snoRNA binding+++GO:0030621///U4 snRNA binding+++GO:0030622///U4atac snRNA binding+++GO:0034511///U3 snoRNA binding+++GO:0034512///box C/D snoRNA binding+++GO:0051117///ATPase binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0000470///maturation of LSU-rRNA+++GO:0000492///box C/D snoRNP assembly+++GO:0006397///mRNA processing+++GO:0007338///single fertilization+++GO:0008380///RNA splicing+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis" 208263 208263 'Tor1aip1' mRNA 1308.01 1439.38 1410.25 22.8 25.13 26.97 28 26.39 25.57 24.96666667 26.65333333 1813.07 1662.89 1575.22 1385.88 1683.726667 0.00267968 0.26699997 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051117///ATPase binding GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061024///membrane organization+++GO:0071763///nuclear membrane organization+++GO:0090435///protein localization to nuclear envelope 208266 208266 'Dot1l' mRNA 763 734 520 5.29 5.04 3.96 4.48 3.86 4.14 4.763333333 4.16 704 604 633 672.3333333 647 0.726131866 -0.061404858 00310///Lysine degradation+++05202///Transcriptional misregulation in cancer "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle" GO:0008134///transcription factor binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0031151///histone methyltransferase activity (H3-K79 specific)+++GO:0042054///histone methyltransferase activity GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006348///chromatin silencing at telomere+++GO:0008284///positive regulation of cell proliferation+++GO:0010467///gene expression+++GO:0031509///telomeric heterochromatin assembly+++GO:0032259///methylation+++GO:0034729///histone H3-K79 methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046425///regulation of JAK-STAT cascade+++GO:0051726///regulation of cell cycle+++GO:2000677///regulation of transcription regulatory region DNA binding 208285 208285 'Cyp4f17' mRNA 1315.46 1256.65 1478.5 24.95 23.55 29.75 13.41 14.66 15.6 26.08333333 14.55666667 810.96 850.42 904.16 1350.203333 855.18 3.97E-10 -0.674750668 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" 208292 208292 'Zfp871' mRNA 2332 2369 2130 11.23 11.21 10.88 7.55 6.05 7.23 11.10666667 6.943333333 1805 1413 1677 2277 1631.666667 3.82E-09 -0.492915644 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 20832 20832 'Ssr4' mRNA 1937 1967 1777 161.5 162.4 156.88 219.47 226.95 225.08 160.26 223.8333333 3002 3022 2974 1893.666667 2999.333333 6.22E-25 0.653282688 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 20833 20833 'Ssrp1' mRNA 2610 2670 2050 51.82 51.93 43.26 47.67 44.95 45.46 49.00333333 46.02666667 2757 2535 2551 2443.333333 2614.333333 0.332091072 0.090254688 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0035101///FACT complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0031491///nucleosome binding+++GO:0042393///histone binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:1902275///regulation of chromatin organization 208366 208366 'Rpp40' mRNA 71 70.11 97 3.33 3.24 5.21 4.77 5.96 5.28 3.926666667 5.336666667 114 134 114 79.37 120.6666667 0.037876068 0.58732783 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030677///ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex GO:0000171///ribonuclease MRP activity+++GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0008033///tRNA processing+++GO:1905267///endonucleolytic cleavage involved in tRNA processing" 20840 20840 'Stac' mRNA 951.42 895.34 890.93 18.96 18.13 19.59 8.97 9.31 8.82 18.89333333 9.033333333 499.99 500.05 481.1 912.5633333 493.7133333 3.88E-19 -0.898303206 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042383///sarcolemma GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0034605///cellular response to heat+++GO:0035556///intracellular signal transduction+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2001259///positive regulation of cation channel activity 20841 20841 'Zfp143' mRNA 416 496 431 7.59 8.97 8.36 7.38 7.5 6.79 8.306666667 7.223333333 466 462 415 447.6666667 447.6666667 0.951838943 -0.010867522 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0031519///PcG protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:1905382///positive regulation of snRNA transcription by RNA polymerase II 20842 20842 'Stag1' mRNA 984 1035.23 904.53 6.36 6.59 6.43 6.12 6.02 5.93 6.46 6.023333333 997.44 943.24 939.07 974.5866667 959.9166667 0.792212428 -0.032206044 04110///Cell cycle GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0008278///cohesin complex+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0097431///mitotic spindle pole GO:0003682///chromatin binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly 208426 208426 'Iqcj' mRNA 7 3 2.26 0.26 0.11 0.09 0 0 0.2 0.153333333 0.066666667 0 0 6 4.086666667 2 0.641550165 -0.992565443 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 20843 20843 'Stag2' mRNA 1328 1425 1281 11.99 12.65 12.28 9.37 8.36 7.87 12.30666667 8.533333333 1194 1041 975 1344.666667 1070 2.13E-04 -0.341677974 04110///Cell cycle "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0008278///cohesin complex+++GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole" GO:0003682///chromatin binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0019827///stem cell population maintenance+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly 208431 208431 'Shroom4' mRNA 125 113 65 0.8 0.71 0.44 0.77 0.45 0.61 0.65 0.61 139 79 106 101 108 0.828065242 0.091196765 GO:0001725///stress fiber+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016324///apical plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043296///apical junction complex GO:0003779///actin binding+++GO:0045159///myosin II binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0050890///cognition 208439 208439 'Klhl29' mRNA 39 30 32 0.29 0.22 0.25 0.31 0.18 0.17 0.253333333 0.22 48 27 25 33.66666667 33.33333333 0.960771365 -0.031456713 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 20844 20844 'Stam' mRNA 924 940 913 13.53 13.54 14.19 14.76 12.63 13.32 13.75333333 13.57 1160 970 1014 925.6666667 1048 0.108753851 0.165598971 04144///Endocytosis+++04630///JAK-STAT signaling pathway GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0033565///ESCRT-0 complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding+++GO:0044389///ubiquitin-like protein ligase binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:1903543///positive regulation of exosomal secretion+++GO:1903551///regulation of extracellular exosome assembly 208440 208440 'Dip2c' mRNA 202 218 160 1.31 1.39 1.1 1.35 1.36 1.27 1.266666667 1.326666667 239 235 218 193.3333333 230.6666667 0.211861053 0.247721387 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 208449 208449 'Sgms1' mRNA 1954 1975 1524 31.78 32.27 24.55 30.82 28.08 28.58 29.53333333 29.16 2255 1967 2012 1817.666667 2078 0.043791854 0.185169565 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0002950///ceramide phosphoethanolamine synthase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033188///sphingomyelin synthase activity+++GO:0047493///ceramide cholinephosphotransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0010628///positive regulation of gene expression+++GO:0016310///phosphorylation+++GO:0046513///ceramide biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 20845 20845 'Star' mRNA 143 130 124 1.91 1.7 1.75 0.96 1.03 1.16 1.786666667 1.05 83 87 97 132.3333333 89 0.017837045 -0.582311004 04913///Ovarian steroidogenesis+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++04979///Cholesterol metabolism GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0030061///mitochondrial crista+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0120020///intermembrane cholesterol transfer activity "GO:0006082///organic acid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0006869///lipid transport+++GO:0007420///brain development+++GO:0007584///response to nutrient+++GO:0007623///circadian rhythm+++GO:0008203///cholesterol metabolic process+++GO:0008211///glucocorticoid metabolic process+++GO:0008584///male gonad development+++GO:0009635///response to herbicide+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0010288///response to lead ion+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0015918///sterol transport+++GO:0016101///diterpenoid metabolic process+++GO:0017085///response to insecticide+++GO:0017143///insecticide metabolic process+++GO:0018879///biphenyl metabolic process+++GO:0018894///dibenzo-p-dioxin metabolic process+++GO:0018958///phenol-containing compound metabolic process+++GO:0018963///phthalate metabolic process+++GO:0031667///response to nutrient levels+++GO:0032367///intracellular cholesterol transport+++GO:0032869///cellular response to insulin stimulus+++GO:0034698///response to gonadotropin+++GO:0035094///response to nicotine+++GO:0035457///cellular response to interferon-alpha+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0042747///circadian sleep/wake cycle, REM sleep+++GO:0043434///response to peptide hormone+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0044255///cellular lipid metabolic process+++GO:0044321///response to leptin+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045471///response to ethanol+++GO:0046677///response to antibiotic+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048545///response to steroid hormone+++GO:0050769///positive regulation of neurogenesis+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051412///response to corticosterone+++GO:0060992///response to fungicide+++GO:0061370///testosterone biosynthetic process+++GO:0070859///positive regulation of bile acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071236///cellular response to antibiotic+++GO:0071248///cellular response to metal ion+++GO:0071276///cellular response to cadmium ion+++GO:0071312///cellular response to alkaloid+++GO:0071320///cellular response to cAMP+++GO:0071333///cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071378///cellular response to growth hormone stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071872///cellular response to epinephrine stimulus+++GO:0120009///intermembrane lipid transfer" 20846 20846 'Stat1' mRNA 4718.61 4833.12 4544 75.56 75.75 75.63 88.79 95.41 92.61 75.64666667 92.27 6391 6666 6397.02 4698.576667 6484.673333 1.90E-15 0.454038953 "04062///Chemokine signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05212///Pancreatic cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0035035///histone acetyltransferase binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0003340///negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0008015///blood circulation+++GO:0009617///response to bacterium+++GO:0010742///macrophage derived foam cell differentiation+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032869///cellular response to insulin stimulus+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0034240///negative regulation of macrophage fusion+++GO:0034340///response to type I interferon+++GO:0035456///response to interferon-beta+++GO:0035458///cellular response to interferon-beta+++GO:0042127///regulation of cell proliferation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0043434///response to peptide hormone+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046725///negative regulation by virus of viral protein levels in host cell+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051591///response to cAMP+++GO:0051607///defense response to virus+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060337///type I interferon signaling pathway+++GO:0061326///renal tubule development+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0071407///cellular response to organic cyclic compound+++GO:0072136///metanephric mesenchymal cell proliferation involved in metanephros development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072308///negative regulation of metanephric nephron tubule epithelial cell differentiation" 20847 20847 'Stat2' mRNA 1521.74 1585.5 1603.5 18.25 18.7 20.4 29.76 27.44 27.97 19.11666667 28.39 2856.37 2572.68 2599.96 1570.246667 2676.336667 3.47E-24 0.755405545 04062///Chemokine signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044389///ubiquitin-like protein ligase binding" "GO:0001932///regulation of protein phosphorylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0090140///regulation of mitochondrial fission" 20848 20848 'Stat3' mRNA 3510 3639 3471 41.71 42.52 43.75 73.93 72.87 72.53 42.66 73.11 7162 6892 6803 3540 6952.333333 1.32E-69 0.961698001 "01521///EGFR tyrosine kinase inhibitor resistance+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04217///Necroptosis+++04550///Signaling pathways regulating pluripotency of stem cells+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05212///Pancreatic cancer+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05417///Lipid and atherosclerosis" GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0031490///chromatin DNA binding+++GO:0031730///CCR5 chemokine receptor binding+++GO:0035259///glucocorticoid receptor binding+++GO:0035591///signaling adaptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070878///primary miRNA binding" "GO:0001659///temperature homeostasis+++GO:0001754///eye photoreceptor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006952///defense response+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0007568///aging+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010507///negative regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0014070///response to organic cyclic compound+++GO:0016310///phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019827///stem cell population maintenance+++GO:0019953///sexual reproduction+++GO:0030335///positive regulation of cell migration+++GO:0030522///intracellular receptor signaling pathway+++GO:0032355///response to estradiol+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032870///cellular response to hormone stimulus+++GO:0033210///leptin-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0040014///regulation of multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0042755///eating behavior+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043434///response to peptide hormone+++GO:0044320///cellular response to leptin stimulus+++GO:0044321///response to leptin+++GO:0045471///response to ethanol+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045820///negative regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048708///astrocyte differentiation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0055091///phospholipid homeostasis+++GO:0060019///radial glial cell differentiation+++GO:0060259///regulation of feeding behavior+++GO:0060396///growth hormone receptor signaling pathway+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0060548///negative regulation of cell death+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071345///cellular response to cytokine stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0072538///T-helper 17 type immune response+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0097009///energy homeostasis+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1902728///positive regulation of growth factor dependent skeletal muscle satellite cell proliferation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904685///positive regulation of metalloendopeptidase activity+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1905618///positive regulation of miRNA mediated inhibition of translation+++GO:2000635///negative regulation of primary miRNA processing+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:2000737///negative regulation of stem cell differentiation+++GO:2001171///positive regulation of ATP biosynthetic process+++GO:2001223///negative regulation of neuron migration" 20849 20849 'Stat4' mRNA 13 3 5 0.28 0.06 0.11 0.62 0.79 0.93 0.15 0.78 35 43 51 7 43 1.19E-05 2.612789255 04217///Necroptosis+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++05161///Hepatitis B+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0008283///cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0071310///cellular response to organic substance" 20850 20850 'Stat5a' mRNA 668.71 633.86 626.11 9.5 8.76 9.38 11.07 12.2 12.19 9.213333333 11.82 897.01 964.8 962.5 642.8933333 941.4366667 7.15E-08 0.539970622 "04012///ErbB signaling pathway+++04217///Necroptosis+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04917///Prolactin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042301///phosphate ion binding+++GO:0043565///sequence-specific DNA binding" "GO:0001553///luteinization+++GO:0001779///natural killer cell differentiation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019218///regulation of steroid metabolic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019530///taurine metabolic process+++GO:0019915///lipid storage+++GO:0030155///regulation of cell adhesion+++GO:0030856///regulation of epithelial cell differentiation+++GO:0030879///mammary gland development+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0033026///negative regulation of mast cell apoptotic process+++GO:0033077///T cell differentiation in thymus+++GO:0038026///reelin-mediated signaling pathway+++GO:0040014///regulation of multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045579///positive regulation of B cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046543///development of secondary female sexual characteristics+++GO:0046544///development of secondary male sexual characteristics+++GO:0048541///Peyer's patch development+++GO:0050729///positive regulation of inflammatory response+++GO:0060056///mammary gland involution+++GO:0060376///positive regulation of mast cell differentiation+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0061030///epithelial cell differentiation involved in mammary gland alveolus development+++GO:0061180///mammary gland epithelium development+++GO:0070668///positive regulation of mast cell proliferation+++GO:0071345///cellular response to cytokine stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus" 208501 208501 'Ndufaf8' mRNA 583 615 709 100.81 106.42 130.18 72.87 102.73 90.16 112.47 88.58666667 479 655 570 635.6666667 568 0.302524973 -0.176103272 04714///Thermogenesis GO:0005739///mitochondrion GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 20851 20851 'Stat5b' mRNA 2595.29 2531.9 2263.89 25.27 24.55 22.67 14.67 15.33 16.28 24.16333333 15.42666667 1765.47 1791.2 1879.5 2463.693333 1812.056667 1.61E-10 -0.452494873 "04012///ErbB signaling pathway+++04062///Chemokine signaling pathway+++04217///Necroptosis+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04917///Prolactin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity" "GO:0001553///luteinization+++GO:0001779///natural killer cell differentiation+++GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006952///defense response+++GO:0006953///acute-phase response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0007548///sex differentiation+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0008284///positive regulation of cell proliferation+++GO:0019218///regulation of steroid metabolic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019530///taurine metabolic process+++GO:0019915///lipid storage+++GO:0030155///regulation of cell adhesion+++GO:0030856///regulation of epithelial cell differentiation+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0032870///cellular response to hormone stimulus+++GO:0033077///T cell differentiation in thymus+++GO:0040014///regulation of multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0042448///progesterone metabolic process+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045579///positive regulation of B cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046543///development of secondary female sexual characteristics+++GO:0046544///development of secondary male sexual characteristics+++GO:0048541///Peyer's patch development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0051272///positive regulation of cellular component movement+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0070669///response to interleukin-2+++GO:0070670///response to interleukin-4+++GO:0070672///response to interleukin-15+++GO:0071363///cellular response to growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0097531///mast cell migration" 208518 208518 'Cep78' mRNA 249 267 141 5.32 5.63 3.23 3.03 4.42 3.61 4.726666667 3.686666667 161 227 186 219 191.3333333 0.49639351 -0.191467247 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0044782///cilium organization 20852 20852 'Stat6' mRNA 2110 2268 2208 30.01 31.73 33.32 40.49 41.41 37.24 31.68666667 39.71333333 3276 3273 2918 2195.333333 3155.666667 1.01E-11 0.510805734 04217///Necroptosis+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05161///Hepatitis B+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045121///membrane raft "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0002829///negative regulation of type 2 immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0007259///JAK-STAT cascade+++GO:0019221///cytokine-mediated signaling pathway+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0034097///response to cytokine+++GO:0035771///interleukin-4-mediated signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048295///positive regulation of isotype switching to IgE isotypes+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0060443///mammary gland morphogenesis+++GO:0070301///cellular response to hydrogen peroxide+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1902170///cellular response to reactive nitrogen species" 20853 20853 'Stau1' mRNA 1882 1936 1924 28.38 28.76 30.77 25.36 25.8 25.35 29.30333333 25.50333333 1935 1921 1870 1914 1908.666667 0.863090843 -0.016663466 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044297///cell body+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding GO:0008298///intracellular mRNA localization+++GO:0034599///cellular response to oxidative stress+++GO:0045070///positive regulation of viral genome replication+++GO:0046726///positive regulation by virus of viral protein levels in host cell+++GO:0050804///modulation of chemical synaptic transmission+++GO:0098963///dendritic transport of messenger ribonucleoprotein complex+++GO:0099010///modification of postsynaptic structure+++GO:1900273///positive regulation of long-term synaptic potentiation 20855 20855 'Stc1' mRNA 83 77 77 1.2 1.1 1.18 4.2 4.47 4.7 1.16 4.456666667 334 347 362 79 347.6666667 2.35E-32 2.126958725 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane GO:0005179///hormone activity+++GO:0042802///identical protein binding GO:0001503///ossification+++GO:0001886///endothelial cell morphogenesis+++GO:0003421///growth plate cartilage axis specification+++GO:0006874///cellular calcium ion homeostasis+++GO:0007165///signal transduction+++GO:0007566///embryo implantation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0014070///response to organic cyclic compound+++GO:0030320///cellular monovalent inorganic anion homeostasis+++GO:0030336///negative regulation of cell migration+++GO:0033280///response to vitamin D+++GO:0035988///chondrocyte proliferation+++GO:0044070///regulation of anion transport+++GO:0046697///decidualization+++GO:0051926///negative regulation of calcium ion transport+++GO:0060348///bone development+++GO:0071320///cellular response to cAMP+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071456///cellular response to hypoxia+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0090280///positive regulation of calcium ion import+++GO:1903403///negative regulation of renal phosphate excretion 20856 20856 'Stc2' mRNA 23 16 9 0.74 0.51 0.31 0.06 0.52 0 0.52 0.193333333 2 18 0 16 6.666666667 0.273331817 -1.244721347 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0042803///protein homodimerization activity GO:0006874///cellular calcium ion homeostasis+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007566///embryo implantation+++GO:0010629///negative regulation of gene expression+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0033280///response to vitamin D+++GO:0034976///response to endoplasmic reticulum stress+++GO:0040015///negative regulation of multicellular organism growth+++GO:0043434///response to peptide hormone+++GO:0046697///decidualization+++GO:0046885///regulation of hormone biosynthetic process+++GO:0055074///calcium ion homeostasis+++GO:0071456///cellular response to hypoxia+++GO:2000118///regulation of sodium-dependent phosphate transport+++GO:2001256///regulation of store-operated calcium entry 208583 208583 'Nek11' mRNA 424.23 463.36 379.2 9.17 9.66 8.6 1.39 1.3 1.2 9.143333333 1.296666667 73 68.09 60.15 422.2633333 67.08 5.71E-51 -2.664309229 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0035556///intracellular signal transduction+++GO:1901990///regulation of mitotic cell cycle phase transition 208595 208595 'Mterf1b' mRNA 90.97 93.53 96.38 1.44 1.59 1.69 1.28 1.39 1.33 1.573333333 1.333333333 89.76 70.35 87.84 93.62666667 82.65 0.551291057 -0.196323673 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0043565///sequence-specific DNA binding "GO:0006353///DNA-templated transcription, termination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006391///transcription initiation from mitochondrial promoter+++GO:0006393///termination of mitochondrial transcription+++GO:0032392///DNA geometric change" 20860 20860 'Sult1e1' mRNA 2 1 4 0.1 0.05 0.2 3.2 2.93 2.83 0.116666667 2.986666667 76 68 65 2.333333333 69.66666667 4.20E-13 4.882797786 00140///Steroid hormone biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0004062///aryl sulfotransferase activity+++GO:0004304///estrone sulfotransferase activity+++GO:0005496///steroid binding+++GO:0008146///sulfotransferase activity+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0047894///flavonol 3-sulfotransferase activity+++GO:0050294///steroid sulfotransferase activity GO:0006068///ethanol catabolic process+++GO:0006711///estrogen catabolic process+++GO:0007565///female pregnancy+++GO:0008210///estrogen metabolic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0051923///sulfation 208606 208606 'Rsrc2' mRNA 1234 1395 1328 31.23 34.77 35.48 30.36 29.31 29.27 33.82666667 29.64666667 1374 1287 1282 1319 1314.333333 0.872036916 -0.018020879 GO:0005575///cellular_component GO:0008150///biological_process 20861 20861 'Stfa1' mRNA 0 0 1.12 0 0 0.28 0 0.42 0.21 0.093333333 0.21 0 2 1 0.373333333 1 0.726099345 1.486127565 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 208613 208613 'Tmem212' mRNA 6 2 4 0.59 0.26 0.42 0 0 0.36 0.423333333 0.12 0 0 4 4 1.333333333 0.431911133 -1.595545449 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 208618 208618 'Etl4' mRNA 1904 1946 1527 15.3 15.86 13.36 7.8 6.26 7.89 14.84 7.316666667 1063 868 1053 1792.333333 994.6666667 1.65E-19 -0.858017766 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0030234///enzyme regulator activity GO:0007275///multicellular organism development+++GO:0048706///embryonic skeletal system development 20862 20862 'Stfa2' mRNA 3 1 4 0.68 0.23 0.96 0.2 0.41 0.63 0.623333333 0.413333333 1 2 3 2.666666667 2 0.847786727 -0.439687049 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 208624 208624 'Alg3' mRNA 516 478 517 21.57 19.91 23.06 27.14 28.15 28.25 21.51333333 27.84666667 733 744 741 503.6666667 739.3333333 1.24E-06 0.540638892 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity" GO:0006486///protein glycosylation 208628 208628 'Kntc1' mRNA 6 8 3 0.06 0.09 0.03 0.54 0.64 0.46 0.06 0.546666667 61 71 49 5.666666667 60.33333333 2.50E-10 3.409245964 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005828///kinetochore microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:1990423///RZZ complex" GO:0003674///molecular_function+++GO:0031267///small GTPase binding GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0051301///cell division+++GO:1903394///protein localization to kinetochore involved in kinetochore assembly 20863 20863 'Stfa3' mRNA 3 1 1 0.72 0.24 0.25 0.42 0 0 0.403333333 0.14 2 0 0 1.666666667 0.666666667 0.66764194 -1.346587537 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 208634 208634 'Tspan10' mRNA 160 144 133 4.4 3.9 3.88 2.8 2.67 2.74 4.06 2.736666667 117 109 111 145.6666667 112.3333333 0.09973801 -0.385290274 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019899///enzyme binding GO:0051604///protein maturation+++GO:0072594///establishment of protein localization to organelle 208638 208638 'Slc25a38' mRNA 783.98 838 728.07 25.3 25.91 24.03 16.59 21.86 20.81 25.08 19.75333333 607 776.95 712.02 783.35 698.6566667 0.191951193 -0.172685437 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015187///glycine transmembrane transporter activity GO:0030218///erythrocyte differentiation+++GO:1904983///glycine import into mitochondrion 208643 208643 'Eif4g1' mRNA 3453 3482 2410 33.87 33.54 25.26 33.87 38.88 36.87 30.89 36.54 3953 4442 4169 3115 4188 1.98E-05 0.424442163 05416///Viral myocarditis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:0016281///eukaryotic translation initiation factor 4F complex+++GO:0098794///postsynapse "GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008135///translation factor activity, RNA binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0042802///identical protein binding" GO:0001662///behavioral fear response+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0010507///negative regulation of autophagy+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010942///positive regulation of cell death+++GO:0030307///positive regulation of cell growth+++GO:0031669///cellular response to nutrient levels+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034645///cellular macromolecule biosynthetic process+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0045666///positive regulation of neuron differentiation+++GO:0097009///energy homeostasis+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1905537///positive regulation of eukaryotic translation initiation factor 4F complex assembly+++GO:1905606///regulation of presynapse assembly+++GO:1905612///positive regulation of mRNA cap binding+++GO:1905618///positive regulation of miRNA mediated inhibition of translation+++GO:1905696///regulation of polysome binding 208647 208647 'Creb3l2' mRNA 1486 1396 1199 24.44 22.59 20.91 21.79 19.25 22.8 22.64666667 21.28 1525 1316 1545 1360.333333 1462 0.376016935 0.094456261 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0000139///Golgi membrane+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097038///perinuclear endoplasmic reticulum "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding" "GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006986///response to unfolded protein+++GO:0007275///multicellular organism development+++GO:0009611///response to wounding+++GO:0010628///positive regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development" 208650 208650 'Cblb' mRNA 444 477 385 3.3 3.36 3.04 3.72 3.15 2.94 3.233333333 3.27 583 489 450 435.3333333 507.3333333 0.148218406 0.210602742 04012///ErbB signaling pathway+++04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++04910///Insulin signaling pathway+++05162///Measles GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0045121///membrane raft GO:0001784///phosphotyrosine residue binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding+++GO:0047690///aspartyltransferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0002669///positive regulation of T cell anergy+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0016567///protein ubiquitination+++GO:0018193///peptidyl-amino acid modification+++GO:0023051///regulation of signaling+++GO:0030155///regulation of cell adhesion+++GO:0031398///positive regulation of protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0042110///T cell activation+++GO:0043087///regulation of GTPase activity+++GO:0043393///regulation of protein binding+++GO:0045732///positive regulation of protein catabolic process+++GO:0046642///negative regulation of alpha-beta T cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:2000583///regulation of platelet-derived growth factor receptor-alpha signaling pathway 208659 208659 'Fam20a' mRNA 1240 1229 1164 27.54 26.7 27.25 35.78 37.21 39.13 27.16333333 37.37333333 1865 1894 1975 1211 1911.333333 9.42E-18 0.647587941 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus "GO:0004674///protein serine/threonine kinase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0043539///protein serine/threonine kinase activator activity" GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0009617///response to bacterium+++GO:0031214///biomineral tissue development+++GO:0044691///tooth eruption+++GO:0055074///calcium ion homeostasis+++GO:0070166///enamel mineralization+++GO:0071902///positive regulation of protein serine/threonine kinase activity 20866 20866 'Stim1' mRNA 1374 1537.01 1346 18.1 19.88 18.88 16.45 16.1 15.7 18.95333333 16.08333333 1433 1373 1331 1419.003333 1379 0.615078002 -0.052004839 04020///Calcium signaling pathway+++04611///Platelet activation GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030426///growth cone+++GO:0032541///cortical endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0044853///plasma membrane raft GO:0002020///protease binding+++GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015279///store-operated calcium channel activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051010///microtubule plus-end binding GO:0002115///store-operated calcium entry+++GO:0005513///detection of calcium ion+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0014902///myotube differentiation+++GO:0032237///activation of store-operated calcium channel activity+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0051924///regulation of calcium ion transport+++GO:0070166///enamel mineralization+++GO:0070588///calcium ion transmembrane transport+++GO:2001256///regulation of store-operated calcium entry 208666 208666 'Diras1' mRNA 34 32 35 0.64 0.59 0.68 0.59 0.72 0.71 0.636666667 0.673333333 36 44 42 33.66666667 40.66666667 0.606835011 0.260696421 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0007165///signal transduction 20867 20867 'Stip1' mRNA 3020 3189 2988 78.44 81.58 82.33 74.7 74.1 67.95 80.78333333 72.25 3307 3203 2912 3065.666667 3140.666667 0.814905037 0.022937253 05020///Prion disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0101031///chaperone complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030544///Hsp70 protein binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0098761///cellular response to interleukin-7 208677 208677 'Creb3l3' mRNA 3 4 0 0.09 0.12 0 0.34 0.32 0.21 0.07 0.29 13 12 8 2.333333333 11 0.049266453 2.246099875 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 20868 20868 'Stk10' mRNA 342 382 383 3.58 3.91 4.25 5.3 4.24 5.03 3.913333333 4.856666667 582 457 533 369 524 3.74E-04 0.49080592 04914///Progesterone-mediated oocyte maturation GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0071593///lymphocyte aggregation+++GO:2000401///regulation of lymphocyte migration 20869 20869 'Stk11' mRNA 705.99 705.12 507.71 18.26 17.37 14.56 14.41 16.95 15.49 16.73 15.61666667 675.91 760.5 723 639.6066667 719.8033333 0.237544719 0.166670471 04068///FoxO signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04530///Tight junction+++04920///Adipocytokine signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0036398///TCR signalosome GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030275///LRR domain binding+++GO:0030295///protein kinase activator activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001558///regulation of cell growth+++GO:0001894///tissue homeostasis+++GO:0001944///vasculature development+++GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007409///axonogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0010212///response to ionizing radiation+++GO:0010508///positive regulation of autophagy+++GO:0016310///phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0032147///activation of protein kinase activity+++GO:0033993///response to lipid+++GO:0036399///TCR signalosome assembly+++GO:0042593///glucose homeostasis+++GO:0043276///anoikis+++GO:0045059///positive thymic T cell selection+++GO:0045722///positive regulation of gluconeogenesis+++GO:0046777///protein autophosphorylation+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0050852///T cell receptor signaling pathway+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051645///Golgi localization+++GO:0051726///regulation of cell cycle+++GO:0051896///regulation of protein kinase B signaling+++GO:0060070///canonical Wnt signaling pathway+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0071493///cellular response to UV-B+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097484///dendrite extension+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901610///positive regulation of vesicle transport along microtubule+++GO:1904262///negative regulation of TORC1 signaling 208691 208691 'Eif5a2' mRNA 864 922 845 9.18 9.63 9.53 12.66 11.74 12.93 9.446666667 12.44333333 1371 1243 1357 877 1323.666667 7.04E-12 0.582250601 GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0003746///translation elongation factor activity+++GO:0043022///ribosome binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0008284///positive regulation of cell proliferation+++GO:0015031///protein transport+++GO:0045901///positive regulation of translational elongation+++GO:0045905///positive regulation of translational termination+++GO:0051028///mRNA transport 20871 20871 'Aurkc' mRNA 4 0 1 0.22 0 0.06 0 0.05 0.11 0.093333333 0.053333333 0 1 3 1.666666667 1.333333333 0.909870718 -0.318783719 "GO:0000775///chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0030496///midbody+++GO:0031616///spindle pole centrosome+++GO:0032133///chromosome passenger complex+++GO:0051233///spindle midzone+++GO:1990385///meiotic spindle midzone" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035174///histone serine kinase activity GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0032465///regulation of cytokinesis+++GO:0035404///histone-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0048599///oocyte development+++GO:0051255///spindle midzone assembly+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle 208715 208715 'Hmgcs1' mRNA 3541 3653 3453 54.92 55.82 57.04 30.63 29.7 29.67 55.92666667 30 2268 2144 2124 3549 2178.666667 1.96E-31 -0.715948252 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism+++00900///Terpenoid backbone biosynthesis+++03320///PPAR signaling pathway" GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004421///hydroxymethylglutaryl-CoA synthase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016853///isomerase activity+++GO:0036094///small molecule binding+++GO:0042803///protein homodimerization activity+++GO:0043177///organic acid binding" "GO:0001889///liver development+++GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0007420///brain development+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0008584///male gonad development+++GO:0009645///response to low light intensity stimulus+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010142///farnesyl diphosphate biosynthetic process, mevalonate pathway+++GO:0014070///response to organic cyclic compound+++GO:0014074///response to purine-containing compound+++GO:0016126///sterol biosynthetic process+++GO:0033197///response to vitamin E+++GO:0034698///response to gonadotropin+++GO:0042493///response to drug+++GO:0046690///response to tellurium ion+++GO:0070723///response to cholesterol+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071397///cellular response to cholesterol+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071407///cellular response to organic cyclic compound" 208718 208718 'Dis3l2' mRNA 810 825 796 13.2 13.13 13.31 7.57 6.65 7.19 13.21333333 7.136666667 532 469 496 810.3333333 499 5.30E-12 -0.712179398 GO:0000178///exosome (RNase complex)+++GO:0000932///P-body+++GO:0005737///cytoplasm GO:0000175///3'-5'-exoribonuclease activity+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005515///protein binding+++GO:0008266///poly(U) RNA binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000278///mitotic cell cycle+++GO:0000291///nuclear-transcribed mRNA catabolic process, exonucleolytic+++GO:0006402///mRNA catabolic process+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010587///miRNA catabolic process+++GO:0019827///stem cell population maintenance+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0051301///cell division+++GO:0051306///mitotic sister chromatid separation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:1990074///polyuridylation-dependent mRNA catabolic process" 20872 20872 'Stk16' mRNA 1372.24 1413.79 1404.54 49.7 50.25 54.19 37.43 38.08 37.82 51.38 37.77666667 1155.04 1149.9 1148.14 1396.856667 1151.026667 5.93E-04 -0.29171867 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0071560///cellular response to transforming growth factor beta stimulus 208727 208727 'Hdac4' mRNA 2016.15 1886.31 1862.11 12.03 11.1 11.88 7.5 6.69 7.38 11.67 7.19 1451.05 1263.63 1392.26 1921.523333 1368.98 1.60E-10 -0.502021234 04371///Apelin signaling pathway+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0017053///transcriptional repressor complex+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0031672///A band+++GO:0032991///protein-containing complex+++GO:0042641///actomyosin GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019789///SUMO transferase activity+++GO:0019901///protein kinase binding+++GO:0030955///potassium ion binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0033613///activating transcription factor binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0002076///osteoblast development+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006476///protein deacetylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010832///negative regulation of myotube differentiation+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016575///histone deacetylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0034983///peptidyl-lysine deacetylation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045820///negative regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0070555///response to interleukin-1+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071260///cellular response to mechanical stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:1902437///positive regulation of male mating behavior+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process" 20873 20873 'Plk4' mRNA 95 74 81 1.47 1.12 1.34 3.2 2.76 3.14 1.31 3.033333333 239 202 225 83.33333333 222 1.79E-11 1.400457694 04068///FoxO signaling pathway GO:0000922///spindle pole+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0032154///cleavage furrow+++GO:0098536///deuterosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007099///centriole replication+++GO:0016310///phosphorylation+++GO:0032465///regulation of cytokinesis+++GO:0046601///positive regulation of centriole replication+++GO:0060271///cilium assembly+++GO:0060707///trophoblast giant cell differentiation+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation 20874 20874 'Slk' mRNA 1680 1767 1619 12.77 13.2 13.05 5.5 4.81 5.42 13.00666667 5.243333333 833 712 794 1688.666667 779.6666667 3.82E-42 -1.126959755 04114///Oocyte meiosis GO:0005737///cytoplasm+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0030334///regulation of cell migration+++GO:0031122///cytoplasmic microtubule organization+++GO:0033129///positive regulation of histone phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0051893///regulation of focal adhesion assembly 208748 208748 'Prrg3' mRNA 1575 1627 1504 13.98 14.21 14.19 7.25 7.26 7.36 14.12666667 7.29 938 915 923 1568.666667 925.3333333 3.23E-23 -0.772598328 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 208768 208768 'Sde2' mRNA 964 1001 1069 16.54 16.9 19.45 16.56 16.64 17.07 17.63 16.75666667 1111 1090 1109 1011.333333 1103.333333 0.320852481 0.111245079 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003684///damaged DNA binding GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0016485///protein processing+++GO:0016567///protein ubiquitination+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0034644///cellular response to UV+++GO:0051301///cell division+++GO:0071156///regulation of cell cycle arrest 20877 20877 'Aurkb' mRNA 3 16 7 0.09 0.46 0.22 10.56 11.08 9.97 0.256666667 10.53666667 421 429 384 8.666666667 411.3333333 8.04E-63 5.559789715 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0010369///chromocenter+++GO:0030496///midbody+++GO:0031616///spindle pole centrosome+++GO:0032133///chromosome passenger complex+++GO:0051233///spindle midzone+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0035174///histone serine kinase activity+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002903///negative regulation of B cell apoptotic process+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007052///mitotic spindle organization+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007568///aging+++GO:0008283///cell proliferation+++GO:0009838///abscission+++GO:0016310///phosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032465///regulation of cytokinesis+++GO:0032466///negative regulation of cytokinesis+++GO:0032467///positive regulation of cytokinesis+++GO:0034501///protein localization to kinetochore+++GO:0034644///cellular response to UV+++GO:0036089///cleavage furrow formation+++GO:0043988///histone H3-S28 phosphorylation+++GO:0044878///mitotic cytokinesis checkpoint+++GO:0051256///mitotic spindle midzone assembly+++GO:0051301///cell division+++GO:0051973///positive regulation of telomerase activity+++GO:1904355///positive regulation of telomere capping+++GO:1905116///positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore 208777 208777 'Sned1' mRNA 2557 2632 2198 14.71 14.91 13.42 40.21 37.11 39.73 14.34666667 39.01666667 8040 7248 7693 2462.333333 7660.333333 2.37E-166 1.627856671 GO:0005576///extracellular region GO:0005112///Notch binding+++GO:0005509///calcium ion binding GO:0007160///cell-matrix adhesion+++GO:0008150///biological_process 20878 20878 'Aurka' mRNA 55.13 27 41 1.64 0.78 1.27 8.69 9.05 9.43 1.23 9.056666667 334 338.13 350 41.04333333 340.71 3.11E-41 3.042153332 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0032133///chromosome passenger complex+++GO:0042585///germinal vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043203///axon hillock+++GO:0045120///pronucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle+++GO:0072687///meiotic spindle+++GO:0097431///mitotic spindle pole GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035174///histone serine kinase activity+++GO:0046982///protein heterodimerization activity GO:0000212///meiotic spindle organization+++GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007052///mitotic spindle organization+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0007098///centrosome cycle+++GO:0007100///mitotic centrosome separation+++GO:0009611///response to wounding+++GO:0009948///anterior/posterior axis specification+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030030///cell projection organization+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032465///regulation of cytokinesis+++GO:0035404///histone-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051642///centrosome localization+++GO:0071539///protein localization to centrosome+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090233///negative regulation of spindle checkpoint+++GO:0097421///liver regeneration+++GO:1900195///positive regulation of oocyte maturation+++GO:1990138///neuron projection extension 208795 208795 'Tmem63a' mRNA 1430 1650 1451 21.63 25.44 24.23 25.92 26.47 26.52 23.76666667 26.30333333 1838 1837 1853.01 1510.333333 1842.67 6.03E-04 0.27636031 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0005227///calcium activated cation channel activity+++GO:0008381///mechanosensitive ion channel activity+++GO:1990760///osmolarity-sensing cation channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 208820 208820 'Triqk' mRNA 217 246 252 8.55 9.56 10.53 3.91 3.34 4.54 9.546666667 3.93 114 95 128 238.3333333 112.3333333 4.52E-08 -1.100030163 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 208836 208836 'Fanci' mRNA 28.1 22.99 17.08 0.35 0.27 0.22 1.09 0.89 1.06 0.28 1.013333333 103.59 83.71 101.09 22.72333333 96.13 1.39E-09 2.090218565 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043240///Fanconi anaemia nuclear complex GO:0070182///DNA polymerase binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031398///positive regulation of protein ubiquitination 208846 208846 'Daam1' mRNA 663 614 551 5.86 5.39 5.18 3.4 3.27 3.47 5.476666667 3.38 438 415 437 609.3333333 430 1.07E-05 -0.512683197 04310///Wnt signaling pathway GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0016043///cellular component organization+++GO:0016055///Wnt signaling pathway+++GO:0030036///actin cytoskeleton organization 208869 208869 'Dock3' mRNA 223 271 185 1.29 1.56 1.16 0.37 0.33 0.45 1.336666667 0.383333333 71 64 85 226.3333333 73.33333333 1.73E-13 -1.631655814 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 20887 20887 'Sult1a1' mRNA 1459.99 1399.95 1361.59 67.62 64.24 66.76 40.72 41.86 39.23 66.20666667 40.60333333 1001.4 1006.03 935.09 1407.176667 980.84 2.06E-10 -0.53163469 05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004062///aryl sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0017067///tyrosine-ester sulfotransferase activity+++GO:0042802///identical protein binding+++GO:0043199///sulfate binding+++GO:0047685///amine sulfotransferase activity+++GO:0047894///flavonol 3-sulfotransferase activity+++GO:0050294///steroid sulfotransferase activity+++GO:0050656///3'-phosphoadenosine 5'-phosphosulfate binding GO:0006584///catecholamine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008217///regulation of blood pressure+++GO:0014823///response to activity+++GO:0017085///response to insecticide+++GO:0017144///drug metabolic process+++GO:0018960///4-nitrophenol metabolic process+++GO:0042403///thyroid hormone metabolic process+++GO:0051384///response to glucocorticoid+++GO:0051923///sulfation 208884 208884 'Zdhhc9' mRNA 317 321 43 5.75 5.78 0.84 1.63 1.53 1.38 4.123333333 1.513333333 103 94 84 227 93.66666667 0.157289764 -1.257756485 04391///Hippo signaling pathway - fly GO:0000139///Golgi membrane+++GO:0002178///palmitoyltransferase complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031228///intrinsic component of Golgi membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0043849///Ras palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation 208890 208890 'Slc26a7' mRNA 316 304 270 3.37 3.01 3.15 0.41 0.31 0.27 3.176666667 0.33 42 35 28 296.6666667 35 1.14E-42 -3.094169335 04971///Gastric acid secretion GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0055038///recycling endosome membrane GO:0005253///anion channel activity+++GO:0005254///chloride channel activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity GO:0001696///gastric acid secretion+++GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0008272///sulfate transport+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 208898 208898 'Unc13c' mRNA 95 121 95 0.55 0.7 0.6 0.2 0.16 0.22 0.616666667 0.193333333 38 31 43 103.6666667 37.33333333 1.28E-06 -1.483138765 04721///Synaptic vesicle cycle GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098831///presynaptic active zone cytoplasmic component GO:0001566///non-kinase phorbol ester receptor activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0019992///diacylglycerol binding+++GO:0046872///metal ion binding "GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0031914///negative regulation of synaptic plasticity+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035556///intracellular signal transduction+++GO:0061789///dense core granule priming+++GO:0099525///presynaptic dense core vesicle exocytosis" 20890 20890 'Wnt8a' mRNA 10 10 1 0.39 0.38 0.04 0.2 0 0.03 0.27 0.076666667 6 0 1 7 2.333333333 0.317666062 -1.586416374 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity GO:0000902///cell morphogenesis+++GO:0003002///regionalization+++GO:0007275///multicellular organism development+++GO:0007492///endoderm development+++GO:0009949///polarity specification of anterior/posterior axis+++GO:0010085///polarity specification of proximal/distal axis+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0032880///regulation of protein localization+++GO:0045165///cell fate commitment+++GO:0048561///establishment of animal organ orientation+++GO:0060070///canonical Wnt signaling pathway+++GO:0062009///secondary palate development 208908 208908 'Ccdc62' mRNA 199 186 183 7.11 6.24 5.63 2.55 2.85 2.01 6.326666667 2.47 81 99 66 189.3333333 82 8.56E-08 -1.21771816 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity GO:0001835///blastocyst hatching+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus 20892 20892 'Cenpx' mRNA 928 926 869 96.87 95.43 96.94 112.47 127.77 115.56 96.41333333 118.6 1181 1286 1162 907.6666667 1209.666667 1.00E-05 0.404096173 03460///Fanconi anemia pathway "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0043240///Fanconi anaemia nuclear complex+++GO:0071821///FANCM-MHF complex" GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding GO:0000712///resolution of meiotic recombination intermediates+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031297///replication fork processing+++GO:0051301///cell division+++GO:0051382///kinetochore assembly 208922 208922 'Cpeb3' mRNA 817 809 712 7.15 6.9 6.6 2.66 2.59 2.7 6.883333333 2.65 352 331 346 779.3333333 343 4.21E-28 -1.193970065 04114///Oocyte meiosis+++04320///Dorso-ventral axis formation+++04914///Progesterone-mediated oocyte maturation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0030014///CCR4-NOT complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0097440///apical dendrite+++GO:0098794///postsynapse+++GO:1990124///messenger ribonucleoprotein complex "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0043022///ribosome binding+++GO:0045182///translation regulator activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0007616///long-term memory+++GO:0017148///negative regulation of translation+++GO:0045727///positive regulation of translation+++GO:0048167///regulation of synaptic plasticity+++GO:0050955///thermoception+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0060998///regulation of dendritic spine development+++GO:0060999///positive regulation of dendritic spine development+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0071230///cellular response to amino acid stimulus+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1900248///negative regulation of cytoplasmic translational elongation+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1900365///positive regulation of mRNA polyadenylation+++GO:2000766///negative regulation of cytoplasmic translation" 20893 20893 'Bhlhe40' mRNA 1566 1721 1688 27.56 29.81 31.51 34.88 35.74 36.57 29.62666667 35.73 2280 2282 2315 1658.333333 2292.333333 4.08E-09 0.454397528 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0043426///MRF binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0009416///response to light stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis" 208936 208936 'Adamts18' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001654///eye development+++GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0090331///negative regulation of platelet aggregation 208943 208943 'Myo5c' mRNA 574 607 491 4.52 4.75 4.14 4.5 4.01 4.49 4.47 4.333333333 648 569 629 557.3333333 615.3333333 0.304949394 0.133556556 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030141///secretory granule+++GO:0031982///vesicle GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0030050///vesicle transport along actin filament+++GO:0032254///establishment of secretory granule localization 208967 208967 'Thnsl1' mRNA 541 516.14 537 5.96 5.81 6.48 3.68 3.72 2.55 6.083333333 3.316666667 354.19 330 253.64 531.38 312.61 7.13E-08 -0.780680775 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 208968 208968 'Zfp280c' mRNA 316 338 303 3.96 4.11 4.07 2.53 2.47 2.82 4.046666667 2.606666667 234 226 252 319 237.3333333 0.005056595 -0.437222426 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 20897 20897 'Stra6' mRNA 1197 1260 1174 22.03 23.35 23.16 3.49 3.02 3.41 22.84666667 3.306666667 207 178 199 1210.333333 194.6666667 1.54E-129 -2.648442918 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:0034632///retinol transmembrane transporter activity+++GO:0038023///signaling receptor activity GO:0001568///blood vessel development+++GO:0001822///kidney development+++GO:0003184///pulmonary valve morphogenesis+++GO:0003281///ventricular septum development+++GO:0007507///heart development+++GO:0007612///learning+++GO:0007631///feeding behavior+++GO:0030324///lung development+++GO:0030325///adrenal gland development+++GO:0030540///female genitalia development+++GO:0034633///retinol transport+++GO:0042297///vocal learning+++GO:0043010///camera-type eye development+++GO:0043583///ear development+++GO:0043585///nose morphogenesis+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0048286///lung alveolus development+++GO:0048520///positive regulation of behavior+++GO:0048546///digestive tract morphogenesis+++GO:0048566///embryonic digestive tract development+++GO:0048589///developmental growth+++GO:0048745///smooth muscle tissue development+++GO:0048844///artery morphogenesis+++GO:0050890///cognition+++GO:0050905///neuromuscular process+++GO:0060322///head development+++GO:0060323///head morphogenesis+++GO:0060325///face morphogenesis+++GO:0060426///lung vasculature development+++GO:0060539///diaphragm development+++GO:0060900///embryonic camera-type eye formation+++GO:0061029///eyelid development in camera-type eye+++GO:0061038///uterus morphogenesis+++GO:0061143///alveolar primary septum development+++GO:0061156///pulmonary artery morphogenesis+++GO:0061205///paramesonephric duct development+++GO:0071939///vitamin A import+++GO:0097070///ductus arteriosus closure 208982 208982 'Hmgcll1' mRNA 364.91 381.74 310.5 2.14 2.48 2.19 1.19 0.95 1.17 2.27 1.103333333 201.74 171.34 212.53 352.3833333 195.2033333 4.67E-08 -0.862373299 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism+++04146///Peroxisome" GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003824///catalytic activity+++GO:0004419///hydroxymethylglutaryl-CoA lyase activity+++GO:0016829///lyase activity+++GO:0016833///oxo-acid-lyase activity+++GO:0046872///metal ion binding GO:0006552///leucine catabolic process+++GO:0006629///lipid metabolic process+++GO:0046951///ketone body biosynthetic process 208990 208990 'Npb' mRNA 20 13 11 3.02 1.96 1.8 2.34 2.31 2.02 2.26 2.223333333 18 17 15 14.66666667 16.66666667 0.843314991 0.17765797 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001664///G protein-coupled receptor binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007631///feeding behavior 208994 208994 'Fam83b' mRNA 136 130 161 1.2 1.07 1.44 0.82 0.69 0.69 1.236666667 0.733333333 107 93 88 142.3333333 96 0.018298432 -0.586218062 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005154///epidermal growth factor receptor binding+++GO:0019901///protein kinase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0036313///phosphatidylinositol 3-kinase catalytic subunit binding GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008283///cell proliferation 209003 209003 'Rbmx2' mRNA 159 179 180 5.28 5.86 6.34 5.03 6.9 5.79 5.826666667 5.906666667 174 233 194 172.6666667 200.3333333 0.388017784 0.203457186 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 209005 209005 'Fsip2l' mRNA 3 1 4 0.08 0.02 0.11 0 0.05 0 0.07 0.016666667 0 2 0 2.666666667 0.666666667 0.416454525 -2.01673236 GO:0003674///molecular_function GO:0008150///biological_process 20901 20901 'Strap' mRNA 1821 1789 1776 38.19 36.94 39.51 48.85 47.35 45.37 38.21333333 47.19 2679 2536 2409 1795.333333 2541.333333 6.41E-12 0.488601983 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:1990447///U2 snRNP binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0016310///phosphorylation+++GO:0022618///ribonucleoprotein complex assembly+++GO:0030182///neuron differentiation+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0048856///anatomical structure development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation" 209011 209011 'Sirt7' mRNA 1056 1122 1015 34.78 36.52 35.49 36.17 36.59 34.48 35.59666667 35.74666667 1251 1233 1156 1064.333333 1213.333333 0.048834371 0.178150726 00760///Nicotinate and nicotinamide metabolism GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005731///nucleolus organizer region+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0035861///site of double-strand break GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019213///deacetylase activity+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0036055///protein-succinyllysine desuccinylase activity+++GO:0046872///metal ion binding+++GO:0061697///protein-glutaryllysine deglutarylase activity+++GO:0070403///NAD+ binding+++GO:0097372///NAD-dependent histone deacetylase activity (H3-K18 specific) GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0006111///regulation of gluconeogenesis+++GO:0006281///DNA repair+++GO:0006282///regulation of DNA repair+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007072///positive regulation of transcription involved in exit from mitosis+++GO:0007129///synapsis+++GO:0009303///rRNA transcription+++GO:0010529///negative regulation of transposition+++GO:0010821///regulation of mitochondrion organization+++GO:0016570///histone modification+++GO:0031397///negative regulation of protein ubiquitination+++GO:0036049///peptidyl-lysine desuccinylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046825///regulation of protein export from nucleus+++GO:0061698///protein deglutarylation+++GO:0061699///peptidyl-lysine deglutarylation+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:1901836///regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1990258///histone glutamine methylation+++GO:2000234///positive regulation of rRNA processing+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 209012 209012 'Ulk4' mRNA 598 662 601 7.66 8.43 8.28 1.28 0.9 1.54 8.123333333 1.24 115 79 134 620.3333333 109.3333333 5.34E-53 -2.516959482 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000226///microtubule cytoskeleton organization+++GO:0003351///epithelial cilium movement+++GO:0006468///protein phosphorylation+++GO:0007420///brain development+++GO:0010467///gene expression+++GO:0010975///regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0021591///ventricular system development+++GO:0022008///neurogenesis+++GO:0022010///central nervous system myelination+++GO:0022038///corpus callosum development+++GO:0030534///adult behavior+++GO:0032053///ciliary basal body organization+++GO:0035082///axoneme assembly+++GO:0035176///social behavior+++GO:0036445///neuronal stem cell division+++GO:0043408///regulation of MAPK cascade+++GO:0044458///motile cilium assembly+++GO:0046328///regulation of JNK cascade+++GO:0090036///regulation of protein kinase C signaling+++GO:0090660///cerebrospinal fluid circulation+++GO:0097154///GABAergic neuron differentiation+++GO:0150076///neuroinflammatory response+++GO:1900744///regulation of p38MAPK cascade+++GO:2001222///regulation of neuron migration 209018 209018 'Vps8' mRNA 505 534 554 5.17 5.38 6.01 5.73 5.94 5.19 5.52 5.62 639 647 563 531 616.3333333 0.127575973 0.201273073 GO:0005769///early endosome+++GO:0033263///CORVET complex GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0034058///endosomal vesicle fusion 209027 209027 'Pycr1' mRNA 65 78 70 1.66 2.2 1.9 1.58 2.28 2.3 1.92 2.053333333 63 94 97 71 84.66666667 0.499262306 0.246094704 00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion GO:0004735///pyrroline-5-carboxylate reductase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding GO:0006561///proline biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0034599///cellular response to oxidative stress+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0055129///L-proline biosynthetic process+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 209032 209032 'Zc3hav1l' mRNA 122 111 104 0.99 0.88 0.89 0.54 0.56 0.4 0.92 0.5 77 78 55 112.3333333 70 0.012651424 -0.69304292 GO:0005829///cytosol GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 209039 209039 'Tns2' mRNA 2576 2751 2143 29.49 30.94 25.9 25.28 23.5 25.45 28.77666667 24.74333333 2565 2321 2487 2490 2457.666667 0.802709994 -0.026873816 GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005102///signaling receptor binding+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0008285///negative regulation of cell proliferation+++GO:0014850///response to muscle activity+++GO:0019725///cellular homeostasis+++GO:0032963///collagen metabolic process+++GO:0035264///multicellular organism growth+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048871///multicellular organismal homeostasis 209047 209047 'Gipc3' mRNA 631 557 405 10.71 8.69 7.18 1.11 0.79 1.38 8.86 1.093333333 74 54 81 531 69.66666667 1.56E-52 -2.93576616 GO:0008150///biological_process 20905 20905 'Sts' mRNA 3 3 0 0.11 0.11 0 0 0.03 0.07 0.073333333 0.033333333 0 1 2 2 1 0.740077658 -0.969257464 00140///Steroid hormone biosynthesis GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0004773///steryl-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007565///female pregnancy+++GO:0007611///learning or memory+++GO:0008202///steroid metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0009268///response to pH+++GO:0014070///response to organic cyclic compound+++GO:0043434///response to peptide hormone+++GO:0043627///response to estrogen 20907 20907 'Stx1a' mRNA 89 77 92 2.34 1.99 2.56 3.51 2.68 2.26 2.296666667 2.816666667 153 115 96 86 121.3333333 0.09516042 0.478607389 04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle+++04911///Insulin secretion+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0008076///voltage-gated potassium channel complex+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0042641///actomyosin+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0045202///synapse+++GO:0048787///presynaptic active zone membrane+++GO:0070032///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex+++GO:0070033///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane "GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0019855///calcium channel inhibitor activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0032028///myosin head/neck binding+++GO:0042802///identical protein binding+++GO:0043008///ATP-dependent protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding" GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0009629///response to gravity+++GO:0010701///positive regulation of norepinephrine secretion+++GO:0010807///regulation of synaptic vesicle priming+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016192///vesicle-mediated transport+++GO:0016925///protein sumoylation+++GO:0017156///calcium ion regulated exocytosis+++GO:0017157///regulation of exocytosis+++GO:0030073///insulin secretion+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0032940///secretion by cell+++GO:0033605///positive regulation of catecholamine secretion+++GO:0035493///SNARE complex assembly+++GO:0045055///regulated exocytosis+++GO:0045921///positive regulation of exocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0046879///hormone secretion+++GO:0048278///vesicle docking+++GO:0048488///synaptic vesicle endocytosis+++GO:0061025///membrane fusion+++GO:0072657///protein localization to membrane+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:2000463///positive regulation of excitatory postsynaptic potential 20908 20908 'Stx3' mRNA 438 391 308 7.38 6.47 5.48 6.95 7.35 6.82 6.443333333 7.04 477 499 457 379 477.6666667 0.025368117 0.327511664 04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030141///secretory granule+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031201///SNARE complex+++GO:0042470///melanosome+++GO:0042581///specific granule+++GO:0042582///azurophil granule+++GO:0042589///zymogen granule membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0048787///presynaptic active zone membrane+++GO:0097470///ribbon synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:1990796///photoreceptor cell terminal bouton GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0050544///arachidonic acid binding GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0008284///positive regulation of cell proliferation+++GO:0016081///synaptic vesicle docking+++GO:0016192///vesicle-mediated transport+++GO:0031175///neuron projection development+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0045785///positive regulation of cell adhesion+++GO:0048278///vesicle docking+++GO:0050921///positive regulation of chemotaxis+++GO:0060291///long-term synaptic potentiation+++GO:0061025///membrane fusion+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2000010///positive regulation of protein localization to cell surface 209086 209086 'Samd9l' mRNA 1332 1280 1280 13.33 12.61 13.6 14.97 14.16 14.22 13.18 14.45 1722 1592 1585 1297.333333 1633 6.44E-05 0.319196426 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome GO:0005515///protein binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0017145///stem cell division+++GO:0034058///endosomal vesicle fusion+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0042176///regulation of protein catabolic process+++GO:0048536///spleen development 20909 20909 'Stx4a' mRNA 432 390 376 15.77 13.69 14.19 17.32 16.32 19.7 14.55 17.78 534 497 581 399.3333333 537.3333333 0.001160336 0.417216615 04130///SNARE interactions in vesicular transport+++04962///Vasopressin-regulated water reabsorption GO:0000322///storage vacuole+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0031201///SNARE complex+++GO:0032589///neuron projection membrane+++GO:0035749///myelin sheath adaxonal region+++GO:0036477///somatodendritic compartment+++GO:0042383///sarcolemma+++GO:0042581///specific granule+++GO:0043197///dendritic spine+++GO:0043219///lateral loop+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0016230///sphingomyelin phosphodiesterase activator activity+++GO:0030507///spectrin binding+++GO:0031267///small GTPase binding GO:0002639///positive regulation of immunoglobulin production+++GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0008284///positive regulation of cell proliferation+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016192///vesicle-mediated transport+++GO:0017157///regulation of exocytosis+++GO:0030335///positive regulation of cell migration+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0034394///protein localization to cell surface+++GO:0034599///cellular response to oxidative stress+++GO:0035493///SNARE complex assembly+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0043085///positive regulation of catalytic activity+++GO:0043311///positive regulation of eosinophil degranulation+++GO:0045785///positive regulation of cell adhesion+++GO:0048278///vesicle docking+++GO:0048284///organelle fusion+++GO:0050921///positive regulation of chemotaxis+++GO:0060291///long-term synaptic potentiation+++GO:0061025///membrane fusion+++GO:0065003///protein-containing complex assembly+++GO:0071346///cellular response to interferon-gamma+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903575///cornified envelope assembly+++GO:2000010///positive regulation of protein localization to cell surface 20910 20910 'Stxbp1' mRNA 1084 995 645 15.12 13.64 9.53 8.28 10.03 9.32 12.76333333 9.21 683 809 748 908 746.6666667 0.069302595 -0.282600972 04721///Synaptic vesicle cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0031091///platelet alpha granule+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098891///extrinsic component of presynaptic active zone membrane+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0047485///protein N-terminus binding "GO:0002576///platelet degranulation+++GO:0003006///developmental process involved in reproduction+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0007274///neuromuscular synaptic transmission+++GO:0007412///axon target recognition+++GO:0010807///regulation of synaptic vesicle priming+++GO:0015031///protein transport+++GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0016192///vesicle-mediated transport+++GO:0031333///negative regulation of protein complex assembly+++GO:0031338///regulation of vesicle fusion+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032355///response to estradiol+++GO:0035493///SNARE complex assembly+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045921///positive regulation of exocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0050821///protein stabilization+++GO:0060292///long-term synaptic depression+++GO:0070527///platelet aggregation+++GO:0071346///cellular response to interferon-gamma+++GO:0072659///protein localization to plasma membrane+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:0106022///positive regulation of vesicle docking+++GO:1903296///positive regulation of glutamate secretion, neurotransmission+++GO:2000367///regulation of acrosomal vesicle exocytosis" 20911 20911 'Stxbp2' mRNA 1909.83 1986.15 2102.87 44.09 45.04 52.33 51.9 50.97 52.63 47.15333333 51.83333333 2417.28 2318.69 2375.27 1999.616667 2370.413333 0.005391116 0.231038213 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030141///secretory granule+++GO:0032991///protein-containing complex+++GO:0042581///specific granule+++GO:0042582///azurophil granule+++GO:0042589///zymogen granule membrane+++GO:0044194///cytolytic granule+++GO:0045335///phagocytic vesicle+++GO:0070820///tertiary granule+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0030348///syntaxin-3 binding GO:0001909///leukocyte mediated cytotoxicity+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043304///regulation of mast cell degranulation+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043312///neutrophil degranulation+++GO:0071346///cellular response to interferon-gamma 20912 20912 'Stxbp3' mRNA 1452 1412 1452 33.74 32.3 35.79 31.68 30.87 27.92 33.94333333 30.15666667 1568 1492 1338 1438.666667 1466 0.905938796 0.013572613 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule+++GO:0031091///platelet alpha granule+++GO:0042581///specific granule+++GO:0045335///phagocytic vesicle+++GO:0070820///tertiary granule+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0044877///protein-containing complex binding GO:0001678///cellular glucose homeostasis+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0022615///protein to membrane docking+++GO:0030073///insulin secretion+++GO:0032868///response to insulin+++GO:0043312///neutrophil degranulation+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0046325///negative regulation of glucose import+++GO:0070527///platelet aggregation+++GO:0071346///cellular response to interferon-gamma 20913 20913 'Stxbp4' mRNA 2897.51 2875.26 2694.74 28.69 27.7 28.52 15.41 15.48 14.55 28.30333333 15.14666667 1640.84 1507.78 1621.03 2822.503333 1589.883333 2.50E-37 -0.83980697 GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0005515///protein binding+++GO:0019905///syntaxin binding GO:0006605///protein targeting+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008286///insulin receptor signaling pathway+++GO:0010827///regulation of glucose transmembrane transport+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0050821///protein stabilization+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:1902808///positive regulation of cell cycle G1/S phase transition 209131 209131 'Snx30' mRNA 326.63 261.47 141.5 2.24 1.73 1.06 2.2 2.21 2.25 1.676666667 2.22 367.81 361.26 374.46 243.2 367.8433333 0.006656717 0.599639439 GO:0005737///cytoplasm GO:0035091///phosphatidylinositol binding GO:0015031///protein transport 20916 20916 'Sucla2' mRNA 2421 2413 2605 65.16 63.92 74.35 64.09 66.38 65.44 67.81 65.30333333 2742 2753 2688 2479.666667 2727.666667 0.156671796 0.123142673 00020///Citrate cycle (TCA cycle)+++00640///Propanoate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0042709///succinate-CoA ligase complex+++GO:0043209///myelin sheath GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004774///succinate-CoA ligase activity+++GO:0004775///succinate-CoA ligase (ADP-forming) activity+++GO:0004776///succinate-CoA ligase (GDP-forming) activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006099///tricarboxylic acid cycle+++GO:0006104///succinyl-CoA metabolic process+++GO:0006105///succinate metabolic process 20917 20917 'Suclg2' mRNA 1127 1182 1114 23.24 24.05 24.38 22.88 22.71 21.78 23.89 22.45666667 1250 1207 1169 1141 1208.666667 0.482568569 0.071324091 00020///Citrate cycle (TCA cycle)+++00640///Propanoate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0042709///succinate-CoA ligase complex+++GO:0045244///succinate-CoA ligase complex (GDP-forming) GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004775///succinate-CoA ligase (ADP-forming) activity+++GO:0004776///succinate-CoA ligase (GDP-forming) activity+++GO:0004777///succinate-semialdehyde dehydrogenase (NAD+) activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016874///ligase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006099///tricarboxylic acid cycle+++GO:0006104///succinyl-CoA metabolic process+++GO:0006105///succinate metabolic process 20918 20918 'Eif1' mRNA 18317.67 17143.13 14182.16 883.75 816.56 725.95 647.86 662.12 647.44 808.7533333 652.4733333 15414.24 15365.47 14896.72 16547.65333 15225.47667 0.074035327 -0.127418235 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016282///eukaryotic 43S preinitiation complex GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0009048///dosage compensation by inactivation of X chromosome 209186 209186 'Acnat2' mRNA 22.01 13.3 20.84 0.65 0.38 0.65 0.31 0.55 0.32 0.56 0.393333333 12.29 22.14 12.3 18.71666667 15.57666667 0.748435514 -0.269977342 00120///Primary bile acid biosynthesis+++00430///Taurine and hypotaurine metabolism+++01040///Biosynthesis of unsaturated fatty acids+++04146///Peroxisome+++04976///Bile secretion GO:0005777///peroxisome "GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process 209195 209195 'Clic6' mRNA 365 436 342 5.28 6.21 5.25 1.97 2.28 2.19 5.58 2.146666667 157 177 169 381 167.6666667 6.25E-14 -1.191733837 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0008022///protein C-terminus binding+++GO:0031749///D2 dopamine receptor binding+++GO:0031750///D3 dopamine receptor binding+++GO:0031751///D4 dopamine receptor binding+++GO:0042802///identical protein binding GO:0006749///glutathione metabolic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport 209200 209200 'Dtx3l' mRNA 567.35 552.94 505.8 5.84 5.6 5.52 11.08 11.79 11.12 5.653333333 11.33 1239.13 1287.51 1204.81 542.03 1243.816667 2.79E-38 1.189658701 04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex GO:0004842///ubiquitin-protein transferase activity+++GO:0004857///enzyme inhibitor activity+++GO:0008047///enzyme activator activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097677///STAT family protein binding "GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007219///Notch signaling pathway+++GO:0008333///endosome to lysosome transport+++GO:0010390///histone monoubiquitination+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0032092///positive regulation of protein binding+++GO:0033522///histone H2A ubiquitination+++GO:0033523///histone H2B ubiquitination+++GO:0035563///positive regulation of chromatin binding+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051607///defense response to virus+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901666///positive regulation of NAD+ ADP-ribosyltransferase activity+++GO:1902966///positive regulation of protein localization to early endosome+++GO:2000646///positive regulation of receptor catabolic process+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining" 209212 209212 'Osgin2' mRNA 334 338 312 4.9 5 5.05 4.72 5.44 5.4 4.983333333 5.186666667 361 410 394 328 388.3333333 0.121673337 0.233990448 GO:0005575///cellular_component GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0030308///negative regulation of cell growth 20922 20922 'Supt4a' mRNA 1336.36 1367.15 1341.01 132.16 134.34 140.68 119.43 129.78 116.18 135.7266667 121.7966667 1379.86 1459.69 1295.48 1348.173333 1378.343333 0.863090843 0.019571719 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032044///DSIF complex GO:0000993///RNA polymerase II complex binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006397///mRNA processing+++GO:0032785///negative regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II" 209224 209224 'Enox2' mRNA 368 333 348 6.68 5.68 6.68 3.88 3.08 3.79 6.346666667 3.583333333 242 191 238 349.6666667 223.6666667 3.60E-05 -0.658685599 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity GO:0007624///ultradian rhythm+++GO:0022900///electron transport chain+++GO:0040008///regulation of growth+++GO:0048511///rhythmic process 209225 209225 'Zfp710' mRNA 794 811 648 8.87 8.77 7.96 10.11 9.06 10.32 8.533333333 9.83 1027 889 1002 751 972.6666667 4.08E-04 0.364288521 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 209239 209239 'Gan' mRNA 61 44 42 0.96 0.68 0.7 0.44 0.32 0.48 0.78 0.413333333 32 23 34 49 29.66666667 0.090842622 -0.734421677 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0007010///cytoskeleton organization+++GO:0016567///protein ubiquitination 20924 20924 'Supt5' mRNA 3390 3417 2983 52.39 51.93 48.88 40.91 41.08 37.53 51.06666667 39.84 3047 2993 2709 3263.333333 2916.333333 0.016350965 -0.171907815 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032044///DSIF complex GO:0003682///chromatin binding+++GO:0003729///mRNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016239///positive regulation of macroautophagy+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032785///negative regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1900364///negative regulation of mRNA polyadenylation" 20926 20926 'Supt6' mRNA 2065 2011 1962 17.71 16.94 17.81 13.66 13.06 13.45 17.48666667 13.39 1837 1714 1750 2012.666667 1767 0.006675151 -0.200043505 GO:0005634///nucleus+++GO:0008023///transcription elongation factor complex+++GO:0035327///transcriptionally active chromatin GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0042393///histone binding GO:0001825///blastocyst formation+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010793///regulation of mRNA export from nucleus+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034728///nucleosome organization+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0045191///regulation of isotype switching+++GO:0050684///regulation of mRNA processing+++GO:0051028///mRNA transport+++GO:0051147///regulation of muscle cell differentiation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0070827///chromatin maintenance 209268 209268 'Igsf1' mRNA 12 7 7 0.29 0.18 0.11 0.31 0.17 0.06 0.193333333 0.18 14 9 2 8.666666667 8.333333333 0.95505854 -0.071334092 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015026///coreceptor activity+++GO:0034711///inhibin binding+++GO:0038102///activin receptor antagonist activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity" 20927 20927 'Abcc8' mRNA 108 119 101 1.17 1.27 1.16 0.3 0.23 0.14 1.2 0.223333333 32 24 14 109.3333333 23.33333333 4.95E-11 -2.24062713 02010///ABC transporters+++04911///Insulin secretion+++04930///Type II diabetes mellitus GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0008282///inward rectifying potassium channel+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane+++GO:0042383///sarcolemma "GO:0000166///nucleotide binding+++GO:0005267///potassium channel activity+++GO:0005524///ATP binding+++GO:0008281///sulfonylurea receptor activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0044325///ion channel binding" GO:0001678///cellular glucose homeostasis+++GO:0006813///potassium ion transport+++GO:0007565///female pregnancy+++GO:0007613///memory+++GO:0008542///visual learning+++GO:0009268///response to pH+++GO:0010043///response to zinc ion+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016525///negative regulation of angiogenesis+++GO:0032496///response to lipopolysaccharide+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0034220///ion transmembrane transport+++GO:0042493///response to drug+++GO:0043268///positive regulation of potassium ion transport+++GO:0046676///negative regulation of insulin secretion+++GO:0050768///negative regulation of neurogenesis+++GO:0055085///transmembrane transport+++GO:0060253///negative regulation of glial cell proliferation+++GO:0061045///negative regulation of wound healing+++GO:0061855///negative regulation of neuroblast migration+++GO:0071310///cellular response to organic substance+++GO:0071805///potassium ion transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:1900721///positive regulation of uterine smooth muscle relaxation+++GO:1903818///positive regulation of voltage-gated potassium channel activity+++GO:1905075///positive regulation of tight junction disassembly+++GO:1905604///negative regulation of maintenance of permeability of blood-brain barrier 20928 20928 'Abcc9' mRNA 130.52 149.7 121.54 0.93 1.05 0.92 0.48 0.42 0.45 0.966666667 0.45 77.88 65.48 69.45 133.92 70.93666667 1.70E-04 -0.932919061 02010///ABC transporters GO:0001669///acrosomal vesicle+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0008282///inward rectifying potassium channel+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030017///sarcomere+++GO:0030315///T-tubule+++GO:0042383///sarcolemma "GO:0000166///nucleotide binding+++GO:0005261///cation channel activity+++GO:0005267///potassium channel activity+++GO:0005524///ATP binding+++GO:0008281///sulfonylurea receptor activity+++GO:0015459///potassium channel regulator activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0019905///syntaxin binding+++GO:0022857///transmembrane transporter activity+++GO:0036094///small molecule binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:1901363///heterocyclic compound binding" GO:0006813///potassium ion transport+++GO:0033198///response to ATP+++GO:0051607///defense response to virus+++GO:0055085///transmembrane transport+++GO:0061337///cardiac conduction+++GO:0071805///potassium ion transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 209294 209294 'Csta1' mRNA 0 7 4 0 0.14 0.09 0 0.07 0.02 0.076666667 0.03 0 4 1 3.666666667 1.666666667 0.610437478 -1.13079352 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 20930 20930 'Surf1' mRNA 1148.97 1230.87 1226.92 66.44 71.18 76.65 56.43 54.46 55.66 71.42333333 55.51666667 1112.91 1052.92 1069 1202.253333 1078.276667 0.076299194 -0.170100213 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004129///cytochrome-c oxidase activity GO:0006119///oxidative phosphorylation+++GO:0022900///electron transport chain+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:1902600///proton transmembrane transport 20931 20931 'Surf2' mRNA 348.21 340.98 332.73 18.59 17.82 18.64 21.98 21.35 20.39 18.35 21.24 476.49 451.49 428.07 340.64 452.0166667 0.002662083 0.397601088 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0008150///biological_process 209318 209318 'Gps1' mRNA 2806 2931 2854 85.05 88.04 92.32 78.85 78.43 84.73 88.47 80.67 2979 2890 3094 2863.666667 2987.666667 0.569653187 0.048799186 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008180///COP9 signalosome GO:0005515///protein binding GO:0000338///protein deneddylation 20932 20932 'Surf4' mRNA 5448.82 5929.15 5625.34 119.57 129.1 128.81 215.67 239.47 226.54 125.8266667 227.2266667 11132.59 11697.6 11005.93 5667.77 11278.70667 9.73E-60 0.981199063 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0005515///protein binding GO:0007030///Golgi organization+++GO:0010638///positive regulation of organelle organization 20933 20933 'Med22' mRNA 1041 1071 785 18.56 18.96 16.02 16.62 17.65 17.55 17.84666667 17.27333333 1104 1057 1085 965.6666667 1082 0.163885201 0.157934395 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity GO:0006357///regulation of transcription by RNA polymerase II 209334 209334 'Gen1' mRNA 51.56 38.6 25.88 0.57 0.41 0.3 0.62 0.72 0.74 0.426666667 0.693333333 67.08 76.29 77.79 38.68 73.72 0.009661321 0.946449952 GO:0005634///nucleus+++GO:0005813///centrosome GO:0000287///magnesium ion binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0017108///5'-flap endonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010824///regulation of centrosome duplication+++GO:0031297///replication fork processing+++GO:0071139///resolution of recombination intermediates+++GO:0071140///resolution of mitotic recombination intermediates+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 20935 20935 'Surf6' mRNA 559 591 558 10.25 10.66 10.85 9.99 8.48 8.77 10.58666667 9.08 627 520 533 569.3333333 560 0.822791725 -0.037043558 GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0003723///RNA binding GO:0042254///ribosome biogenesis+++GO:0042255///ribosome assembly+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042274///ribosomal small subunit biogenesis 209351 209351 'Wfdc6a' mRNA 2 1 5 0.17 0.08 0.45 0.07 0.15 0.16 0.233333333 0.126666667 1 2 2 2.666666667 1.666666667 0.748070175 -0.713875511 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0032991///protein-containing complex GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0042742///defense response to bacterium+++GO:0090281///negative regulation of calcium ion import+++GO:1901318///negative regulation of flagellated sperm motility 209354 209354 'Eif2b1' mRNA 726 698.04 661 20.53 19.45 19.83 22.09 21.16 21.73 19.93666667 21.66 897.99 839.9 855.15 695.0133333 864.3466667 0.002114517 0.302072438 05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0014003///oligodendrocyte development+++GO:0043434///response to peptide hormone+++GO:0044237///cellular metabolic process+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity+++GO:1990928///response to amino acid starvation 209357 209357 'Gtf2h3' mRNA 360 355 423 7.49 7.27 9.34 8.25 7.52 8.72 8.033333333 8.163333333 456 406 467 379.3333333 443 0.20001688 0.206909522 03022///Basal transcription factors+++03420///Nucleotide excision repair+++05203///Viral carcinogenesis GO:0000438///core TFIIH complex portion of holo TFIIH complex+++GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0097550///transcriptional preinitiation complex GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding "GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain" 209361 209361 'Taf3' mRNA 832 822 815 9.27 9 9.63 7.28 6.23 6.84 9.3 6.783333333 752 629 685 823 688.6666667 0.011659468 -0.270622452 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0031965///nuclear membrane GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0051457///maintenance of protein location in nucleus 20937 20937 'Suv39h1' mRNA 342 312 271 6.39 5.48 5.22 6.35 6.74 6.04 5.696666667 6.376666667 411 410 371 308.3333333 397.3333333 0.015031498 0.356900036 00310///Lysine degradation "GO:0000775///chromosome, centromeric region+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005694///chromosome+++GO:0033553///rDNA heterochromatin" GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008276///protein methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0047485///protein N-terminus binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000183///chromatin silencing at rDNA+++GO:0001835///blastocyst hatching+++GO:0006282///regulation of DNA repair+++GO:0006323///DNA packaging+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006364///rRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008340///determination of adult lifespan+++GO:0030154///cell differentiation+++GO:0030500///regulation of bone mineralization+++GO:0031507///heterochromatin assembly+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0036123///histone H3-K9 dimethylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0040014///regulation of multicellular organism growth+++GO:0042754///negative regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051567///histone H3-K9 methylation+++GO:0071456///cellular response to hypoxia+++GO:1900114///positive regulation of histone H3-K9 trimethylation+++GO:2000772///regulation of cellular senescence" 209378 209378 'Itih5' mRNA 10435 11195 10366 69.27 73.04 72.99 100.78 95.73 98.65 71.76666667 98.38666667 17484 16229 16580 10665.33333 16764.33333 7.69E-38 0.640438853 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0008150///biological_process+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030212///hyaluronan metabolic process 209387 209387 'Trim30d' mRNA 82.96 60.51 90.33 1.25 1.23 1.57 4.81 5.58 5.32 1.35 5.236666667 373.19 314.99 359.08 77.93333333 349.0866667 1.42E-27 2.154856716 05170///Human immunodeficiency virus 1 infection GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990462///omegasome "GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000209///protein polyubiquitination+++GO:0002218///activation of innate immune response+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070534///protein K63-linked ubiquitination+++GO:1902187///negative regulation of viral release from host cell" 209416 209416 'Gpkow' mRNA 1061 1121 1246 16.12 16.75 20.08 16.08 16.04 16.51 17.65 16.21 1218 1187 1211 1142.666667 1205.333333 0.640888539 0.061328758 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 209446 209446 'Tfe3' mRNA 1133 1367 1220 19.58 23.65 22.69 32.55 31.3 29.73 21.97333333 31.19333333 2115 1981 1869 1240 1988.333333 8.32E-15 0.669159517 04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0045670///regulation of osteoclast differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0120163///negative regulation of cold-induced thermogenesis" 209456 209456 'Trp53bp2' mRNA 1850 1977 1849 22.75 23.91 24.12 15.92 14.49 15.48 23.59333333 15.29666667 1490 1325 1403 1892 1406 6.17E-09 -0.440737585 04390///Hippo signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm GO:0002039///p53 binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0051059///NF-kappaB binding GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010212///response to ionizing radiation+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1901216///positive regulation of neuron death 209462 209462 'Hace1' mRNA 269 232 196 3.87 3.35 3.05 2.17 2.96 2.76 3.423333333 2.63 171 229 211 232.3333333 203.6666667 0.386928419 -0.195159854 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0032580///Golgi cisterna membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0030334///regulation of cell migration+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0061025///membrane fusion+++GO:0070936///protein K48-linked ubiquitination 20947 20947 'Swap70' mRNA 831 840 806 11.08 11 11.37 15.65 16.54 15.24 11.15 15.81 1349 1394 1275 825.6666667 1339.333333 2.72E-15 0.686578911 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0016444///somatic cell DNA recombination+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032880///regulation of protein localization+++GO:0033633///negative regulation of cell-cell adhesion mediated by integrin+++GO:0045190///isotype switching+++GO:0051017///actin filament bundle assembly+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:1902309///negative regulation of peptidyl-serine dephosphorylation 209478 209478 'Tbc1d12' mRNA 114 104 98 1.62 1.49 1.49 1.14 1.52 1.35 1.533333333 1.336666667 90 116 102 105.3333333 102.6666667 0.886537466 -0.045397303 GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0055037///recycling endosome GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:2000785///regulation of autophagosome assembly 209488 209488 'Hsh2d' mRNA 8 6 2 0.4 0.3 0.11 0.48 0.45 0.4 0.27 0.443333333 11 10 9 5.333333333 10 0.390976876 0.90989529 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0030674///protein binding, bridging" GO:0002903///negative regulation of B cell apoptotic process+++GO:0007165///signal transduction+++GO:0042110///T cell activation+++GO:0051902///negative regulation of mitochondrial depolarization 209497 209497 'Tmem164' mRNA 2168 2114 1624 25 24.2 20.71 12.48 17.47 14.44 23.30333333 14.79666667 1290 1725 1413 1968.666667 1476 3.53E-04 -0.418808774 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 209540 209540 'Rtl9' mRNA 21 11 20 0.19 0.1 0.19 0.02 0.03 0.06 0.16 0.036666667 2 4 8 17.33333333 4.666666667 0.026099884 -1.90842969 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 20955 20955 'Vamp7' mRNA 817 810 854 17.67 17.22 19.57 19.9 20.67 19.93 18.15333333 20.16666667 1060 1074 1028 827 1054 6.11E-04 0.336553148 04130///SNARE interactions in vesicular transport GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030175///filopodium+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031091///platelet alpha granule+++GO:0031143///pseudopodium+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0035577///azurophil granule membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098686///hippocampal mossy fiber to CA3 synapse GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding "GO:0006887///exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006906///vesicle fusion+++GO:0006911///phagocytosis, engulfment+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0034197///triglyceride transport+++GO:0035493///SNARE complex assembly+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0043308///eosinophil degranulation+++GO:0043312///neutrophil degranulation+++GO:0043320///natural killer cell degranulation+++GO:0047496///vesicle transport along microtubule+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:1900483///regulation of protein targeting to vacuolar membrane+++GO:1903595///positive regulation of histamine secretion by mast cell" 209550 209550 'Rad51ap2' mRNA 24 33 19 0.41 0.56 0.34 0.11 0.03 0.03 0.436666667 0.056666667 4 2 2 25.33333333 2.666666667 6.09E-05 -3.253957561 GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0008150///biological_process 209558 209558 'Enpp3' mRNA 57 65 78 1.12 1.25 1.62 2.18 2.84 2.38 1.33 2.466666667 128 163 135 66.66666667 142 4.76E-05 1.07624016 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00500///Starch and sucrose metabolism+++00740///Riboflavin metabolism+++00760///Nicotinate and nicotinamide metabolism+++00770///Pantothenate and CoA biosynthesis GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003824///catalytic activity+++GO:0004528///phosphodiesterase I activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0036218///dTTP diphosphatase activity+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity GO:0002276///basophil activation involved in immune response+++GO:0006220///pyrimidine nucleotide metabolic process+++GO:0006796///phosphate-containing compound metabolic process+++GO:0008152///metabolic process+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0033007///negative regulation of mast cell activation involved in immune response+++GO:0046034///ATP metabolic process+++GO:0050728///negative regulation of inflammatory response+++GO:0070667///negative regulation of mast cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 20957 20957 'Sycp1' mRNA 3 5 5 0.05 0.08 0.08 0.04 0.01 0.07 0.07 0.04 2 1 5 4.333333333 2.666666667 0.675662818 -0.716641558 "GO:0000775///chromosome, centromeric region+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0000801///central element+++GO:0000802///transverse filament+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding GO:0000711///meiotic DNA repair synthesis+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0007283///spermatogenesis+++GO:0032880///regulation of protein localization+++GO:0035092///sperm chromatin condensation+++GO:0051026///chiasma assembly+++GO:0051289///protein homotetramerization+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051878///lateral element assembly 209584 209584 'Tyw3' mRNA 200.77 223.26 169.99 2.46 2.69 2.21 1.36 1.51 1.45 2.453333333 1.44 127.35 138.61 131.61 198.0066667 132.5233333 0.003805461 -0.586866447 GO:0005737///cytoplasm GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016740///transferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 209586 209586 'Nudcd3' mRNA 2943 3089 3014 40.13 41.42 43.62 30.06 30.48 30.69 41.72333333 30.41 2538 2514 2509 3015.333333 2520.333333 6.77E-05 -0.271114246 GO:0005737///cytoplasm+++GO:0005868///cytoplasmic dynein complex GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0060271///cilium assembly+++GO:1905793///protein localization to pericentriolar material 209588 209588 'Sectm1a' mRNA 3 3 2 0.12 0.11 0.08 0.85 1.12 0.59 0.103333333 0.853333333 27 34 18 2.666666667 26.33333333 4.35E-05 3.297457184 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity GO:0006955///immune response+++GO:0007165///signal transduction 209590 209590 'Il23r' mRNA 14 6 15 0.31 0.13 0.36 0.14 0.14 0.08 0.266666667 0.12 7 7 4 11.66666667 6 0.313898538 -0.983818236 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++05200///Pathways in cancer+++05321///Inflammatory bowel disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0072536///interleukin-23 receptor complex GO:0004896///cytokine receptor activity+++GO:0005143///interleukin-12 receptor binding+++GO:0019955///cytokine binding+++GO:0042019///interleukin-23 binding+++GO:0042020///interleukin-23 receptor activity GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002443///leukocyte mediated immunity+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006954///inflammatory response+++GO:0007259///JAK-STAT cascade+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0034341///response to interferon-gamma+++GO:0038155///interleukin-23-mediated signaling pathway+++GO:0045087///innate immune response 209601 209601 'Erich3' mRNA 459 462 409 13 12.89 12.29 1.33 1.26 1.07 12.72666667 1.22 54 50 42 443.3333333 48.66666667 1.47E-65 -3.197818379 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 20962 20962 'Sycp3' mRNA 19 18 19 1.05 0.99 1.12 1.02 0.84 1.35 1.053333333 1.07 21 17 27 18.66666667 21.66666667 0.786212496 0.201493553 03440///Homologous recombination "GO:0000775///chromosome, centromeric region+++GO:0000779///condensed chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0000802///transverse filament+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0003677///DNA binding+++GO:0005515///protein binding "GO:0000278///mitotic cell cycle+++GO:0000711///meiotic DNA repair synthesis+++GO:0007049///cell cycle+++GO:0007066///female meiosis sister chromatid cohesion+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0016321///female meiosis chromosome segregation+++GO:0035092///sperm chromatin condensation+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0051026///chiasma assembly+++GO:0051301///cell division+++GO:0051309///female meiosis chromosome separation+++GO:0051321///meiotic cell cycle+++GO:0051878///lateral element assembly+++GO:1990830///cellular response to leukemia inhibitory factor" 20963 20963 'Syk' mRNA 55.65 93.27 51.34 0.54 0.88 0.54 6.14 6.96 6.74 0.653333333 6.613333333 693.78 757.87 733.99 66.75333333 728.5466667 3.18E-87 3.450200208 04064///NF-kappa B signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04380///Osteoclast differentiation+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05152///Tuberculosis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019815///B cell receptor complex+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0032991///protein-containing complex+++GO:0042101///T cell receptor complex+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016170///interleukin-15 receptor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035325///Toll-like receptor binding+++GO:0042169///SH2 domain binding+++GO:0043274///phospholipase binding+++GO:0097110///scaffold protein binding GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001775///cell activation+++GO:0001819///positive regulation of cytokine production+++GO:0001820///serotonin secretion+++GO:0001945///lymph vessel development+++GO:0002092///positive regulation of receptor internalization+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0002283///neutrophil activation involved in immune response+++GO:0002366///leukocyte activation involved in immune response+++GO:0002376///immune system process+++GO:0002554///serotonin secretion by platelet+++GO:0006468///protein phosphorylation+++GO:0006606///protein import into nucleus+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0010543///regulation of platelet activation+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019370///leukotriene biosynthetic process+++GO:0030154///cell differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0031334///positive regulation of protein complex assembly+++GO:0031623///receptor internalization+++GO:0032481///positive regulation of type I interferon production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032752///positive regulation of interleukin-3 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032928///regulation of superoxide anion generation+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035556///intracellular signal transduction+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0038156///interleukin-3-mediated signaling pathway+++GO:0042742///defense response to bacterium+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043313///regulation of neutrophil degranulation+++GO:0043366///beta selection+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045579///positive regulation of B cell differentiation+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0046777///protein autophosphorylation+++GO:0048514///blood vessel morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050764///regulation of phagocytosis+++GO:0050776///regulation of immune response+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050853///B cell receptor signaling pathway+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0071226///cellular response to molecule of fungal origin+++GO:0071396///cellular response to lipid+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0090237///regulation of arachidonic acid secretion+++GO:0090330///regulation of platelet aggregation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:1990858///cellular response to lectin 209630 209630 'Frmd4a' mRNA 1386.58 1460.41 1277.02 8.25 8.54 8.86 8.06 6.94 7.44 8.55 7.48 1335.79 1168.59 1219.37 1374.67 1241.25 0.071829803 -0.15859967 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction "GO:0030674///protein binding, bridging" GO:0050709///negative regulation of protein secretion+++GO:0050714///positive regulation of protein secretion+++GO:0090162///establishment of epithelial cell polarity 20964 20964 'Syn1' mRNA 277 244 192 4.75 4.11 3.48 0.64 0.86 0.69 4.113333333 0.73 43 57 45 237.6666667 48.33333333 1.06E-22 -2.302577029 GO:0000795///synaptonemal complex+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0043209///myelin sheath+++GO:0043229///intracellular organelle+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098993///anchored component of synaptic vesicle membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding GO:0007269///neurotransmitter secretion+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048666///neuron development+++GO:0050808///synapse organization+++GO:0097091///synaptic vesicle clustering+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0099504///synaptic vesicle cycle 209645 209645 'Bend7' mRNA 183 181 122 2.59 2.51 1.86 0.81 0.83 0.91 2.32 0.85 65 66 72 162 67.66666667 2.97E-07 -1.263315693 GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 20965 20965 'Syn2' mRNA 9 13 13 0.15 0.19 0.23 0.13 0.1 0.13 0.19 0.12 9 7 9 11.66666667 8.333333333 0.602930859 -0.501755146 GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0043209///myelin sheath+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding GO:0007269///neurotransmitter secretion+++GO:0017156///calcium ion regulated exocytosis+++GO:0097091///synaptic vesicle clustering+++GO:0099504///synaptic vesicle cycle 209683 209683 'Ttc28' mRNA 488.58 584.31 439 1.78 2.19 1.83 1.08 1.24 1.18 1.933333333 1.166666667 333.13 368.74 350.7 503.9633333 350.8566667 1.13E-04 -0.530416941 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone GO:0019900///kinase binding GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0051301///cell division 20969 20969 'Sdc1' mRNA 233 239 252 4.29 4.23 4.97 13.97 13.2 13.26 4.496666667 13.47666667 859 792 812 241.3333333 821 2.86E-50 1.752652118 04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++05144///Malaria+++05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding GO:0001657///ureteric bud development+++GO:0006954///inflammatory response+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0016477///cell migration+++GO:0042060///wound healing+++GO:0042476///odontogenesis+++GO:0042542///response to hydrogen peroxide+++GO:0048627///myoblast development+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0055002///striated muscle cell development+++GO:0060009///Sertoli cell development+++GO:0060070///canonical Wnt signaling pathway+++GO:1903543///positive regulation of exosomal secretion+++GO:1903553///positive regulation of extracellular exosome assembly 209692 209692 'Dhtkd1' mRNA 440.38 447.47 379.12 4.83 4.73 4.14 2.23 2.3 2.04 4.566666667 2.19 263.07 236.22 218.27 422.3233333 239.1866667 4.96E-09 -0.830236973 00310///Lysine degradation+++00380///Tryptophan metabolism GO:0005739///mitochondrion "GO:0004591///oxoglutarate dehydrogenase (succinyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0030976///thiamine pyrophosphate binding" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006091///generation of precursor metabolites and energy+++GO:0006096///glycolytic process+++GO:0006099///tricarboxylic acid cycle 20970 20970 'Sdc3' mRNA 4091 4476 2621 45.24 48.64 30.9 36.9 36.12 37.98 41.59333333 37 3823 3657 3818 3729.333333 3766 0.963278392 0.013537317 04514///Cell adhesion molecules GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0044393///microspike GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0030334///regulation of cell migration 209707 209707 'Lcorl' mRNA 516.17 568.1 530.56 5.86 5.94 5.77 5.88 5.08 5.4 5.856666667 5.453333333 585.03 505.58 525.15 538.2766667 538.5866667 0.940102711 -0.011909357 GO:0005634///nucleus GO:0003677///DNA binding+++GO:1990226///histone methyltransferase binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II 20971 20971 'Sdc4' mRNA 29853 28605 30040 675.36 636.51 721.11 616.79 563.76 602.55 677.66 594.3666667 31352 27976 29660 29499.33333 29662.66667 0.935175452 -0.006735445 04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++05205///Proteoglycans in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043034///costamere+++GO:0045121///membrane raft GO:0001968///fibronectin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0070053///thrombospondin receptor activity GO:0001657///ureteric bud development+++GO:0001843///neural tube closure+++GO:0010762///regulation of fibroblast migration+++GO:0016477///cell migration+++GO:0042060///wound healing+++GO:0042130///negative regulation of T cell proliferation+++GO:0045860///positive regulation of protein kinase activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:1903543///positive regulation of exosomal secretion+++GO:1903553///positive regulation of extracellular exosome assembly 20972 20972 'Syngr1' mRNA 2732 2634 2126 111.44 108.92 96.1 177.01 210.75 187.17 105.4866667 191.6433333 2989 3361 3024 2497.333333 3124.666667 2.27E-04 0.317268536 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0042470///melanosome+++GO:0045202///synapse GO:0006605///protein targeting+++GO:0045055///regulated exocytosis+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048499///synaptic vesicle membrane organization+++GO:1990830///cellular response to leukemia inhibitory factor 20973 20973 'Syngr2' mRNA 1103 1063 1054 42.78 40.79 43.34 91.53 93.61 96.68 42.30333333 93.94 2711 2704 2766 1073.333333 2727 2.15E-78 1.333527126 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0045202///synapse GO:0005515///protein binding GO:0006605///protein targeting+++GO:0045055///regulated exocytosis+++GO:0048499///synaptic vesicle membrane organization 209737 209737 'Kif15' mRNA 8 10 10 0.09 0.11 0.12 1.23 0.92 1.23 0.106666667 1.126666667 128 93 124 9.333333333 115 1.66E-19 3.6088231 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:1901673///regulation of mitotic spindle assembly 20974 20974 'Syngr3' mRNA 58 101 106 1.69 2.9 3.28 2 2 1.96 2.623333333 1.986666667 79 77 75 88.33333333 77 0.575937352 -0.215915831 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0045202///synapse GO:0005515///protein binding+++GO:0042169///SH2 domain binding+++GO:0047485///protein N-terminus binding GO:0001504///neurotransmitter uptake+++GO:0032411///positive regulation of transporter activity+++GO:0045055///regulated exocytosis 209743 209743 'Minar1' mRNA 26 18 30 0.19 0.14 0.32 0.12 0.02 0.08 0.216666667 0.073333333 13 4 9 24.66666667 8.666666667 0.024810742 -1.536373752 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001525///angiogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0016525///negative regulation of angiogenesis+++GO:0030308///negative regulation of cell growth+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032007///negative regulation of TOR signaling 20975 20975 'Synj2' mRNA 1198.73 1172.41 1062.04 9.27 9.04 8.88 5.03 4.81 4.47 9.063333333 4.77 759.72 710.2 653.48 1144.393333 707.8 2.18E-14 -0.704414386 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031315///extrinsic component of mitochondrial outer membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043679///axon terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse "GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0030165///PDZ domain binding+++GO:0034595///phosphatidylinositol phosphate 5-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0052744///phosphatidylinositol monophosphate phosphatase activity" GO:0007420///brain development+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048312///intracellular distribution of mitochondria+++GO:0048488///synaptic vesicle endocytosis 209760 209760 'Tmc7' mRNA 61 60 59 0.73 0.7 0.75 0.72 0.84 0.85 0.726666667 0.803333333 69 79 79 60 75.66666667 0.346181611 0.324168157 GO:0005575///cellular_component+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 20977 20977 'Syp' mRNA 1138 975 972 25.56 21.56 23.16 3.96 3.34 3.79 23.42666667 3.696666667 203 167 188 1028.333333 186 1.14E-91 -2.479185242 GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043229///intracellular organelle+++GO:0044306///neuron projection terminus+++GO:0044309///neuron spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098685///Schaffer collateral - CA1 synapse GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0017075///syntaxin-1 binding+++GO:0019904///protein domain specific binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006897///endocytosis+++GO:0007268///chemical synaptic transmission+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048488///synaptic vesicle endocytosis+++GO:0071310///cellular response to organic substance+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000474///regulation of opioid receptor signaling pathway 209773 209773 'Dennd2a' mRNA 225 251 248 2.82 3.05 3.32 3.89 2.97 3.01 3.063333333 3.29 358 270 270 241.3333333 299.3333333 0.108976953 0.295132956 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton GO:0005085///guanyl-nucleotide exchange factor activity "GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050790///regulation of catalytic activity" 209776 209776 'Gpr139' mRNA 29 37 37 0.32 0.41 0.44 0.1 0.02 0.01 0.39 0.043333333 10 2 1 34.33333333 4.333333333 2.92E-05 -3.011027307 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 20979 20979 'Syt1' mRNA 492 560 473 5.67 6.4 5.9 0.85 0.69 0.76 5.99 0.766666667 84 69 75 508.3333333 76 1.71E-62 -2.752420645 04721///Synaptic vesicle cycle GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030658///transport vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0042584///chromaffin granule membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0070382///exocytic vesicle+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0030348///syntaxin-3 binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0048306///calcium-dependent protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0061891///calcium ion sensor activity" "GO:0005513///detection of calcium ion+++GO:0007269///neurotransmitter secretion+++GO:0007420///brain development+++GO:0014059///regulation of dopamine secretion+++GO:0016079///synaptic vesicle exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0030154///cell differentiation+++GO:0031340///positive regulation of vesicle fusion+++GO:0033603///positive regulation of dopamine secretion+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0048278///vesicle docking+++GO:0048488///synaptic vesicle endocytosis+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0050806///positive regulation of synaptic transmission+++GO:0051291///protein heterooligomerization+++GO:0051592///response to calcium ion+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0071277///cellular response to calcium ion+++GO:0071911///synchronous neurotransmitter secretion+++GO:0098746///fast, calcium ion-dependent exocytosis of neurotransmitter+++GO:0099502///calcium-dependent activation of synaptic vesicle fusion+++GO:1903235///positive regulation of calcium ion-dependent exocytosis of neurotransmitter+++GO:1903305///regulation of regulated secretory pathway+++GO:1903861///positive regulation of dendrite extension+++GO:2000300///regulation of synaptic vesicle exocytosis" 20980 20980 'Syt2' mRNA 520 585 443 3.83 4.24 3.43 0.36 0.5 0.44 3.833333333 0.433333333 57 77 66 516 66.66666667 2.19E-62 -2.958036898 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0042584///chromaffin granule membrane+++GO:0045202///synapse+++GO:0070382///exocytic vesicle "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0043533///inositol 1,3,4,5 tetrakisphosphate binding+++GO:0046872///metal ion binding" GO:0007269///neurotransmitter secretion+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0030154///cell differentiation+++GO:0048488///synaptic vesicle endocytosis+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0071277///cellular response to calcium ion+++GO:0099502///calcium-dependent activation of synaptic vesicle fusion+++GO:1903861///positive regulation of dendrite extension 20981 20981 'Syt3' mRNA 174 185 148 3.61 3.61 3.36 1.52 1.47 1.52 3.526666667 1.503333333 88 77 79 169 81.33333333 1.73E-06 -1.064212029 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0070382///exocytic vesicle+++GO:0099699///integral component of synaptic membrane "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0006887///exocytosis+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0030154///cell differentiation+++GO:0031340///positive regulation of vesicle fusion+++GO:0051592///response to calcium ion+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 209815 209815 'Tbc1d25' mRNA 321 293 311 7.54 6.75 7.77 7.01 6.77 7.2 7.353333333 6.993333333 340 322 339 308.3333333 333.6666667 0.578189515 0.100796421 GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0090630///activation of GTPase activity+++GO:1901096///regulation of autophagosome maturation 20983 20983 'Syt4' mRNA 515 568 525 7.12 7.7 7.65 21.53 20.39 23.62 7.49 21.84666667 1801 1666 1915 536 1794 1.60E-82 1.731214219 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030667///secretory granule membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0036477///somatodendritic compartment+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0070382///exocytic vesicle+++GO:0097449///astrocyte projection+++GO:0098675///intrinsic component of neuronal dense core vesicle membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098992///neuronal dense core vesicle+++GO:0099012///neuronal dense core vesicle membrane+++GO:0099066///integral component of neuronal dense core vesicle membrane+++GO:1990742///microvesicle GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0030348///syntaxin-3 binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity "GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0007269///neurotransmitter secretion+++GO:0007420///brain development+++GO:0007613///memory+++GO:0014049///positive regulation of glutamate secretion+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0030100///regulation of endocytosis+++GO:0030154///cell differentiation+++GO:0031338///regulation of vesicle fusion+++GO:0031339///negative regulation of vesicle fusion+++GO:0033604///negative regulation of catecholamine secretion+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0046929///negative regulation of neurotransmitter secretion+++GO:0048174///negative regulation of short-term neuronal synaptic plasticity+++GO:0048489///synaptic vesicle transport+++GO:0050709///negative regulation of protein secretion+++GO:0061782///vesicle fusion with vesicle+++GO:0061792///secretory granule maturation+++GO:0071277///cellular response to calcium ion+++GO:0099161///regulation of presynaptic dense core granule exocytosis+++GO:0099183///trans-synaptic signaling by BDNF, modulating synaptic transmission+++GO:0099519///dense core granule cytoskeletal transport+++GO:1903861///positive regulation of dendrite extension+++GO:1905414///negative regulation of dense core granule exocytosis+++GO:1905415///positive regulation of dense core granule exocytosis+++GO:1905433///negative regulation of retrograde trans-synaptic signaling by neuropeptide+++GO:2000301///negative regulation of synaptic vesicle exocytosis" 209837 209837 'Slc38a5' mRNA 112 116 139 3.44 3.51 4.53 5.26 5.09 6.38 3.826666667 5.576666667 197 186 231 122.3333333 204.6666667 7.13E-04 0.726287911 04727///GABAergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005290///L-histidine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015182///L-asparagine transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0022858///alanine transmembrane transporter activity+++GO:0022889///serine transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006867///asparagine transport+++GO:0006868///glutamine transport+++GO:0015804///neutral amino acid transport+++GO:0015816///glycine transport+++GO:0015825///L-serine transport+++GO:0032329///serine transport+++GO:0089709///L-histidine transmembrane transport+++GO:1903713///asparagine transmembrane transport+++GO:1904557///L-alanine transmembrane transport 209966 209966 'Pgbd5' mRNA 60 75 59 1.13 1.42 1.22 2.63 2.33 2.86 1.256666667 2.606666667 157 135 164 64.66666667 152 5.52E-07 1.222929746 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004803///transposase activity+++GO:0016787///hydrolase activity "GO:0032196///transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0098038///non-replicative transposition, DNA-mediated" 210004 210004 'B3gntl1' mRNA 434.1 399.42 341 7.45 6.72 6.17 6.26 5.01 5.42 6.78 5.563333333 430.63 338.51 367.29 391.5066667 378.81 0.75620721 -0.059169526 GO:0005575///cellular_component "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0008150///biological_process 210009 210009 'Mtrr' mRNA 427 411 338 6.8 6.47 5.61 4.96 5.16 5.49 6.293333333 5.203333333 367 373 386 392 375.3333333 0.695398624 -0.07046134 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton "GO:0003958///NADPH-hemoprotein reductase activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0016723///oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor+++GO:0030586///[methionine synthase] reductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0070402///NADPH binding+++GO:0071949///FAD binding" GO:0006306///DNA methylation+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0033353///S-adenosylmethionine cycle+++GO:0043418///homocysteine catabolic process+++GO:0046655///folic acid metabolic process+++GO:0050667///homocysteine metabolic process+++GO:0050821///protein stabilization+++GO:1904042///negative regulation of cystathionine beta-synthase activity 210027 210027 'Slc35f3' mRNA 2 8.01 3.29 0.04 0.12 0.05 0.04 0 0.1 0.07 0.046666667 3 0 7.01 4.433333333 3.336666667 0.852711834 -0.380483563 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0015888///thiamine transport 210029 210029 'Metrnl' mRNA 258 249 181 5.83 5.54 4.34 7.9 8.27 9.92 5.236666667 8.696666667 402 411 489 229.3333333 434 9.31E-09 0.915069861 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0009409///response to cold+++GO:0014850///response to muscle activity+++GO:0045444///fat cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050873///brown fat cell differentiation+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0097009///energy homeostasis 210035 210035 'Nemp1' mRNA 219 221 218 2.42 2.3 2.18 2.14 1.94 2.24 2.3 2.106666667 189 161 190 219.3333333 180 0.125093984 -0.298196265 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0071763///nuclear membrane organization 210044 210044 'Adcy2' mRNA 266 304 218 3.4 3.82 2.96 0.42 0.58 0.67 3.393333333 0.556666667 38 51 58 262.6666667 49 4.03E-26 -2.426607851 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004016///adenylate cyclase activity+++GO:0005524///ATP binding+++GO:0008179///adenylate cyclase binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0030145///manganese ion binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046872///metal ion binding GO:0006171///cAMP biosynthetic process+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:1904322///cellular response to forskolin 210094 210094 'Iglon5' mRNA 2 0 1 0.04 0 0.02 0.14 0.04 0.11 0.02 0.096666667 8 2 6 1 5.333333333 0.166217984 2.390532251 GO:0005576///extracellular region GO:0003674///molecular_function 210104 210104 'Zfp658' mRNA 92 93 98 1.47 1.46 1.63 1.43 1.33 1.59 1.52 1.45 103 93 110 94.33333333 102 0.769735648 0.098881638 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 210105 210105 'Zfp719' mRNA 746 768 696 7.95 8.19 7.9 4.55 4.41 4.13 8.013333333 4.363333333 482 462 421 736.6666667 455 6.02E-11 -0.706130332 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 210106 210106 'Tent4a' mRNA 213 227 189 2.88 3.02 2.71 3.06 2.69 3.13 2.87 2.96 261 225 258 209.6666667 248 0.215150416 0.232192007 03018///RNA degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0031499///TRAMP complex+++GO:0031965///nuclear membrane GO:0000166///nucleotide binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0070568///guanylyltransferase activity GO:0006397///mRNA processing+++GO:0009410///response to xenobiotic stimulus+++GO:0031123///RNA 3'-end processing+++GO:0042493///response to drug+++GO:0043631///RNA polyadenylation+++GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0071076///RNA 3' uridylation+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization 210108 210108 'D130043K22Rik' mRNA 207 178 193 2.15 1.81 2.12 0.09 0.17 0.28 2.026666667 0.18 10 18 30 192.6666667 19.33333333 5.17E-26 -3.327353765 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010996///response to auditory stimulus+++GO:0022008///neurogenesis+++GO:0030517///negative regulation of axon extension+++GO:0033555///multicellular organismal response to stress+++GO:0048692///negative regulation of axon extension involved in regeneration+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:2000171///negative regulation of dendrite development 210126 210126 'Lpp' mRNA 1724.05 1869.01 1545.8 5.72 6.09 5.37 5.71 4.95 6.3 5.726666667 5.653333333 2011 1693 2137 1712.953333 1947 0.072729789 0.175202813 04391///Hippo signaling pathway - fly GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 210135 210135 'Zfp180' mRNA 686 772 730 9.45 10.41 10.63 7.49 6.6 6.41 10.16333333 6.833333333 627 539 519 729.3333333 561.6666667 7.97E-04 -0.390436913 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 210145 210145 'Irgc1' mRNA 0 1 2 0 0.04 0.08 0.03 0.03 0.03 0.04 0.03 1 1 1 1 1 0.997318234 -0.038667294 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 210146 210146 'Irgq' mRNA 1933.43 2010.49 1215.07 16.74 17.11 11.16 6.03 7.73 7.19 15.00333333 6.983333333 802.47 1004.98 925.84 1719.663333 911.0966667 7.51E-05 -0.915761771 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005525///GTP binding GO:0008150///biological_process 210148 210148 'Slc30a6' mRNA 501 593 542 14.31 15.75 16.4 14.87 17.3 13.6 15.48666667 15.25666667 631 725 550 545.3333333 635.3333333 0.15210574 0.209585318 GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0006895///Golgi to endosome transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport 210162 210162 'Zkscan2' mRNA 618.74 658.67 583.23 3.14 3.25 3.16 1.31 1.17 1.26 3.183333333 1.246666667 298.84 254.47 277.82 620.2133333 277.0433333 3.63E-22 -1.176414986 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 210172 210172 'Zfp526' mRNA 247.04 200.58 139.85 2.17 1.84 1.3 1.26 1.28 1.42 1.77 1.32 159.6 151.52 169.67 195.8233333 160.2633333 0.22822383 -0.294421534 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 210274 210274 'Shank2' mRNA 3291 3272 2315 14.44 14.1 10.54 1.4 1.07 1.18 13.02666667 1.216666667 377 279 308 2959.333333 321.3333333 4.92E-172 -3.209635372 04724///Glutamatergic synapse GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005883///neurofilament+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0031526///brush border membrane+++GO:0032279///asymmetric synapse+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048786///presynaptic active zone+++GO:0060170///ciliary membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0008022///protein C-terminus binding+++GO:0017124///SH3 domain binding+++GO:0030160///GKAP/Homer scaffold activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0098919///structural constituent of postsynaptic density "GO:0007416///synapse assembly+++GO:0007420///brain development+++GO:0007584///response to nutrient+++GO:0007612///learning+++GO:0007613///memory+++GO:0008284///positive regulation of cell proliferation+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0030534///adult behavior+++GO:0035176///social behavior+++GO:0035331///negative regulation of hippo signaling+++GO:0035640///exploration behavior+++GO:0048854///brain morphogenesis+++GO:0050807///regulation of synapse organization+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0060997///dendritic spine morphogenesis+++GO:0060999///positive regulation of dendritic spine development+++GO:0071625///vocalization behavior+++GO:0097107///postsynaptic density assembly+++GO:0099562///maintenance of postsynaptic density structure+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential" 210293 210293 'Dock10' mRNA 1086 1123 922 7.75 7.79 6.94 4.86 4.58 4.65 7.493333333 4.696666667 792 727 738 1043.666667 752.3333333 3.00E-07 -0.481285321 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding GO:0001782///B cell homeostasis+++GO:0002315///marginal zone B cell differentiation+++GO:0007264///small GTPase mediated signal transduction+++GO:0030334///regulation of cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060997///dendritic spine morphogenesis 210297 210297 'Lrch2' mRNA 64 78 67 0.7 0.82 0.76 0.49 0.32 0.4 0.76 0.403333333 54 33 41 69.66666667 42.66666667 0.044182921 -0.721519862 GO:0003674///molecular_function 210321 210321 'BC048679' mRNA 74 81 102 8.15 8.97 11.88 0.57 0.19 0.49 9.666666667 0.416666667 6 2 5 85.66666667 4.333333333 8.57E-16 -4.326617202 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 210356 210356 'Nckap5' mRNA 1218.47 1214.87 1048.24 5.39 5.35 4.8 1.41 1.08 0.92 5.18 1.136666667 413.17 312.15 308.08 1160.526667 344.4666667 4.97E-54 -1.763723423 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035371///microtubule plus-end GO:0003674///molecular_function GO:0001578///microtubule bundle formation+++GO:0007019///microtubule depolymerization 210376 210376 'Mtmr9' mRNA 926 877 829 9.28 9.24 8.99 10.69 9.36 9.66 9.17 9.903333333 1121 986 987 877.3333333 1031.333333 0.023330186 0.221418341 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0030234///enzyme regulator activity GO:0006897///endocytosis+++GO:0010507///negative regulation of autophagy+++GO:0010922///positive regulation of phosphatase activity+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0050821///protein stabilization+++GO:0060304///regulation of phosphatidylinositol dephosphorylation 210417 210417 'Thsd7b' mRNA 853 860 790 7.32 7.33 7.18 0.54 0.49 0.5 7.276666667 0.51 73 65 66 834.3333333 68 1.91E-132 -3.62823247 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0031532///actin cytoskeleton reorganization 210503 210503 'Zfp677' mRNA 177 174 152 3.33 3.2 3.04 3.02 2.93 2.44 3.19 2.796666667 185 175 145 167.6666667 168.3333333 0.993407146 -0.004519325 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 210510 210510 'Tdrd6' mRNA 38 13 17 0.28 0.1 0.12 0.07 0.08 0.08 0.166666667 0.076666667 12 14 14 22.66666667 13.33333333 0.279948201 -0.771591708 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:1990904///ribonucleoprotein complex GO:0005515///protein binding GO:0000387///spliceosomal snRNP assembly+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0034587///piRNA metabolic process+++GO:0048477///oogenesis 210529 210529 'Mettl14' mRNA 381 408 372 8.05 8.49 8.34 7.41 6.59 8.07 8.293333333 7.356666667 403 350 425 387 392.6666667 0.961780758 0.009298392 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0016422///mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity+++GO:1904047///S-adenosyl-L-methionine binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0001510///RNA methylation+++GO:0006402///mRNA catabolic process+++GO:0007283///spermatogenesis+++GO:0019827///stem cell population maintenance+++GO:0021861///forebrain radial glial cell differentiation+++GO:0030154///cell differentiation+++GO:0042063///gliogenesis+++GO:0045727///positive regulation of translation+++GO:0061157///mRNA destabilization+++GO:0080009///mRNA methylation+++GO:1901533///negative regulation of hematopoietic progenitor cell differentiation" 210530 210530 'P3h2' mRNA 65 61 36 1.07 0.99 0.63 0.3 0.67 0.72 0.896666667 0.563333333 21 46 49 54 38.66666667 0.327024089 -0.477169082 GO:0005604///basement membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016529///sarcoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0008285///negative regulation of cell proliferation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0032963///collagen metabolic process 210544 210544 'Tbc1d31' mRNA 217 249 191 3.5 3.94 3.24 3.32 3.52 3.92 3.56 3.586666667 238 249 272 219 253 0.303489541 0.200922694 GO:0005813///centrosome GO:0003674///molecular_function GO:0008150///biological_process 210554 210554 'Hus1b' mRNA 0 1 3 0 0.05 0.17 0 0 0.05 0.073333333 0.016666667 0 0 1 1.333333333 0.333333333 0.593573285 -1.948783805 GO:0005730///nucleolus+++GO:0030896///checkpoint clamp complex+++GO:0035861///site of double-strand break GO:0003674///molecular_function GO:0000077///DNA damage checkpoint+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006289///nucleotide-excision repair+++GO:0031573///intra-S DNA damage checkpoint+++GO:0033314///mitotic DNA replication checkpoint+++GO:0044778///meiotic DNA integrity checkpoint 210573 210573 'Tmem151b' mRNA 464.18 471.88 375.01 5.04 5.06 4.36 1.26 0.99 1.23 4.82 1.16 133.85 101.41 125.44 437.0233333 120.2333333 1.01E-30 -1.876623731 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 210582 210582 'Coq10a' mRNA 331 374 324 13.01 14.69 13.99 9.22 8.72 9.06 13.89666667 9 268 241 251 343 253.3333333 0.002940805 -0.44816457 GO:0005739///mitochondrion GO:0048039///ubiquinone binding GO:0006744///ubiquinone biosynthetic process+++GO:0045333///cellular respiration 210583 210583 'Gm4767' mRNA 61.61 119.65 117.27 0.78 1.48 1.57 0.91 1.36 1.16 1.276666667 1.143333333 83.04 121.24 102.65 99.51 102.31 0.943946813 0.029458031 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 210622 210622 'Pamr1' mRNA 62 35 45 1.23 0.69 0.92 2.75 3.08 2.93 0.946666667 2.92 164 178 169 47.33333333 170.3333333 3.13E-12 1.836229322 GO:0005576///extracellular region GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding GO:0006508///proteolysis 210673 210673 'Prrt3' mRNA 1493 1527 1619 21.31 21.41 24.52 4.93 4.93 4.67 22.41333333 4.843333333 398 387 363 1546.333333 382.6666667 5.34E-91 -2.029260733 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 210710 210710 'Gab3' mRNA 52 62 50 1.38 1.62 1.41 4.62 5.42 5.35 1.47 5.13 200 229 224 54.66666667 217.6666667 8.13E-19 1.985201216 GO:0005575///cellular_component GO:0005515///protein binding GO:0030225///macrophage differentiation 210711 210711 'Mcmbp' mRNA 889 938 834 11.48 11.91 11.42 12.58 12.28 12.45 11.60333333 12.43666667 1121 1069 1075 887 1088.333333 0.001363831 0.284483421 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0042555///MCM complex GO:0003682///chromatin binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0007049///cell cycle+++GO:0007062///sister chromatid cohesion+++GO:0051301///cell division 210719 210719 'Mkx' mRNA 114 144 154 1.95 2.42 2.79 2.51 2.4 2.45 2.386666667 2.453333333 169 158 160 137.3333333 162.3333333 0.372677466 0.225301862 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002932///tendon sheath development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0030199///collagen fibril organization+++GO:0030279///negative regulation of ossification+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035990///tendon cell differentiation+++GO:0035992///tendon formation+++GO:0036077///intratendonous ossification+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0071260///cellular response to mechanical stimulus" 210741 210741 'Kcnk12' mRNA 15 9 3 0.3 0.2 0.09 0.08 0.05 0 0.196666667 0.043333333 3 3 0 9 2 0.101393135 -2.16328386 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0030322///stabilization of membrane potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport 210757 210757 'Themis' mRNA 1 3 3 0.02 0.07 0.05 0.28 0.41 0.38 0.046666667 0.356666667 30 43 40 2.333333333 37.66666667 1.50E-07 4.002765863 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0008180///COP9 signalosome GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007275///multicellular organism development+++GO:0043368///positive T cell selection+++GO:0043383///negative T cell selection+++GO:0050852///T cell receptor signaling pathway 210762 210762 'Ppp1r36' mRNA 98 120 96 4.01 4.85 4.16 1.61 1.2 1.42 4.34 1.41 45 33 38 104.6666667 38.66666667 1.46E-06 -1.447692284 GO:0005575///cellular_component GO:0004864///protein phosphatase inhibitor activity+++GO:0019902///phosphatase binding GO:0010923///negative regulation of phosphatase activity 210766 210766 'Brcc3' mRNA 966 942 874 40.93 40.06 39.02 38.33 40.5 40.2 40.00333333 39.67666667 932 997 959 927.3333333 962.6666667 0.727544503 0.044000141 03440///Homologous recombination+++04621///NOD-like receptor signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0000152///nuclear ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0070531///BRCA1-A complex+++GO:0070552///BRISC complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0030234///enzyme regulator activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010165///response to X-ray+++GO:0010212///response to ionizing radiation+++GO:0045739///positive regulation of DNA repair+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0070536///protein K63-linked deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint 210789 210789 'Tbc1d4' mRNA 701.67 696.98 642.81 7.93 7.73 7.35 7.58 7.35 8 7.67 7.643333333 859.15 781.3 850.95 680.4866667 830.4666667 0.006158882 0.277072328 04919///Thyroid hormone signaling pathway+++04931///Insulin resistance+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031982///vesicle GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0031339///negative regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 210801 210801 'Unc5d' mRNA 9 3 8 0.05 0.02 0.05 0.01 0.03 0.01 0.04 0.016666667 2 5 2 6.666666667 3 0.385425111 -1.16773423 04360///Axon guidance GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005042///netrin receptor activity+++GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0021859///pyramidal neuron differentiation+++GO:0038007///netrin-activated signaling pathway+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:2001222///regulation of neuron migration 210808 210808 'Lacc1' mRNA 121 119 131 2.9 2.76 3.24 4.46 4.28 5.5 2.966666667 4.746666667 218 203 248 123.6666667 223 2.46E-05 0.836561391 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum "GO:0004000///adenosine deaminase activity+++GO:0004731///purine-nucleoside phosphorylase activity+++GO:0005507///copper ion binding+++GO:0016682///oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0017061///S-methyl-5-thioadenosine phosphorylase activity+++GO:0046872///metal ion binding+++GO:0047975///guanosine phosphorylase activity" GO:0002221///pattern recognition receptor signaling pathway+++GO:0002376///immune system process+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0006954///inflammatory response+++GO:0030641///regulation of cellular pH+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:1900542///regulation of purine nucleotide metabolic process 210853 210853 'Zfp947' mRNA 49 39.95 29.23 1.02 0.82 0.64 0.56 0.41 0.8 0.826666667 0.59 31.02 22 43.02 39.39333333 32.01333333 0.601066626 -0.291357152 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 210925 210925 'Ints9' mRNA 547 573 559 12.55 12.82 13.5 13.59 15.18 12.91 12.95666667 13.89333333 682 743 627 559.6666667 684 0.022109947 0.277806227 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing 210933 210933 'Adgrb3' mRNA 4 0 1 0.05 0 0.01 0.01 0.02 0 0.02 0.01 1 2 0 1.666666667 1 0.81658754 -0.738560769 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043083///synaptic cleft+++GO:0098794///postsynapse GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007520///myoblast fusion+++GO:0016322///neuron remodeling+++GO:0016525///negative regulation of angiogenesis+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051965///positive regulation of synapse assembly+++GO:0061743///motor learning+++GO:0099558///maintenance of synapse structure 210940 210940 '4931408C20Rik' mRNA 1 0 0 0.01 0 0 0 0.03 0 0.003333333 0.01 0 3 0 0.333333333 1 0.748737812 1.492222257 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 210973 210973 'Kbtbd2' mRNA 757.16 758.61 780.5 11.28 11.17 12.36 11.38 9.97 10.82 11.60333333 10.72333333 875.03 751.44 803.91 765.4233333 810.1266667 0.607260342 0.067590645 GO:0006006///glucose metabolic process+++GO:0006629///lipid metabolic process+++GO:0008152///metabolic process+++GO:0010467///gene expression+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0032868///response to insulin 210982 210982 'Bicral' mRNA 1076.15 1151.87 902.99 5.31 6.06 5.36 3.3 2.29 2.7 5.576666667 2.763333333 688.19 525.4 622.69 1043.67 612.0933333 1.67E-12 -0.779472251 GO:0016514///SWI/SNF complex "GO:0045893///positive regulation of transcription, DNA-templated" 210992 210992 'Lpcat1' mRNA 596 591 357 9.23 8.67 6.14 7.89 8.38 8.12 8.013333333 8.13 565 598 576 514.6666667 579.6666667 0.341470089 0.170594314 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding+++GO:0047159///1-alkenylglycerophosphocholine O-acyltransferase activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047191///1-alkylglycerophosphocholine O-acyltransferase activity+++GO:0047192///1-alkylglycerophosphocholine O-acetyltransferase activity+++GO:0050200///plasmalogen synthase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0043129///surfactant homeostasis+++GO:0045732///positive regulation of protein catabolic process+++GO:0060041///retina development in camera-type eye+++GO:2001246///negative regulation of phosphatidylcholine biosynthetic process 210998 210998 'Fam91a1' mRNA 587 705 572 5.83 6.89 6.05 6.9 5.84 6.41 6.256666667 6.383333333 795 654 718 621.3333333 722.3333333 0.096034479 0.206485188 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0099041///vesicle tethering to Golgi 211006 211006 'Sepsecs' mRNA 479 519 505 5.24 5.5 5.81 4.51 3.41 3.97 5.516666667 3.963333333 487 372 425 501 428 0.090842622 -0.241802205 00450///Selenocompound metabolism+++00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016785///transferase activity, transferring selenium-containing groups+++GO:0098621///phosphoseryl-selenocysteinyl-tRNA selenium transferase activity" GO:0001514///selenocysteine incorporation+++GO:0006412///translation+++GO:0097056///selenocysteinyl-tRNA(Sec) biosynthetic process 211007 211007 'Trim41' mRNA 310 352 277 7.74 8.69 7.57 6.82 6.17 6.88 8 6.623333333 317 272 307 313 298.6666667 0.700665707 -0.076968872 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071225///cellular response to muramyl dipeptide 211064 211064 'Alkbh1' mRNA 385.76 384.23 373 11.3 11.09 11.59 10.1 9.81 10.67 11.32666667 10.19333333 396.47 375.77 405.19 380.9966667 392.4766667 0.863090843 0.030392055 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum "GO:0000049///tRNA binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0016829///lyase activity+++GO:0035515///oxidative RNA demethylase activity+++GO:0035516///oxidative DNA demethylase activity+++GO:0042056///chemoattractant activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0070579///methylcytosine dioxygenase activity+++GO:0103053///1-ethyladenine demethylase activity+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:1990984///tRNA demethylase activity" GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001890///placenta development+++GO:0002101///tRNA wobble cytosine modification+++GO:0006281///DNA repair+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0006448///regulation of translational elongation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0035513///oxidative RNA demethylation+++GO:0035552///oxidative single-stranded DNA demethylation+++GO:0042245///RNA repair+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048589///developmental growth+++GO:0050918///positive chemotaxis+++GO:0070129///regulation of mitochondrial translation+++GO:0070989///oxidative demethylation+++GO:0080111///DNA demethylation+++GO:1990983///tRNA demethylation 211134 211134 'Lzts1' mRNA 274 240 278 2.93 2.51 3.15 2.52 1.73 1.99 2.863333333 2.08 273 183 208 264 221.3333333 0.190245382 -0.272396401 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0016242///negative regulation of macroautophagy+++GO:0044772///mitotic cell cycle phase transition+++GO:0048167///regulation of synaptic plasticity+++GO:0048814///regulation of dendrite morphogenesis 211135 211135 'D130040H23Rik' mRNA 57 72.24 64 1.82 2.2 2.2 1.95 1.72 1.26 2.073333333 1.643333333 70 61 44 64.41333333 58.33333333 0.727824312 -0.154583411 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 211147 211147 'Marchf11' mRNA 41 27 2 1.64 1.03 0.09 0 0 0.08 0.92 0.026666667 0 0 2 23.33333333 0.666666667 3.16E-04 -5.107311065 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination 211151 211151 'Churc1' mRNA 2159.58 2223.32 2075.83 231.52 236.83 236.2 250.36 249.14 242.07 234.85 247.19 2668.32 2583.1 2488.5 2152.91 2579.973333 2.02E-04 0.249827222 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0007498///mesoderm development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 211187 211187 'Lrtm2' mRNA 9958 10095 9765 155.57 155.61 162.37 14.14 12.86 14.1 157.85 13.7 1034 932 1004 9939.333333 990 0 -3.340318203 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008201///heparin binding+++GO:0048495///Roundabout binding GO:0007411///axon guidance+++GO:0050919///negative chemotaxis+++GO:0051965///positive regulation of synapse assembly 211223 211223 'Vmn2r15' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 211228 211228 'Lrrc25' mRNA 70 84 69 3.34 3.9 3.49 33.82 29.23 31.27 3.576666667 31.44 816 688 730 74.33333333 744.6666667 7.98E-104 3.313023275 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 211232 211232 'Cpne9' mRNA 630 634 553 15.6 14.52 13.8 1.92 1.83 1.77 14.64 1.84 94 86 80 605.6666667 86.66666667 4.57E-77 -2.815074095 GO:0005886///plasma membrane GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0030154///cell differentiation+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 211253 211253 'Mtrf1' mRNA 159.61 177.51 180.3 4.57 5.04 5.52 5.48 5.33 5.2 5.043333333 5.336666667 220.39 209.31 202.25 172.4733333 210.65 0.172880858 0.27644746 GO:0005739///mitochondrion GO:0003747///translation release factor activity GO:0006412///translation+++GO:0006415///translational termination+++GO:0070126///mitochondrial translational termination 211255 211255 'Kbtbd7' mRNA 668.52 740.75 696.99 7.92 8.63 8.76 5.78 5.95 5.77 8.436666667 5.833333333 561.38 565.12 543.22 702.0866667 556.5733333 0.001808917 -0.345954244 GO:0031463///Cul3-RING ubiquitin ligase complex GO:0035020///regulation of Rac protein signal transduction+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 211286 211286 'Cln5' mRNA 602 654 538 13.73 14.69 13.02 23.6 22.95 20.63 13.81333333 22.39333333 1190 1130 1007 598 1109 1.01E-18 0.881452499 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005775///vacuolar lumen+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0005515///protein binding+++GO:0005537///mannose binding+++GO:0016798///hydrolase activity, acting on glycosyl bonds" "GO:0006465///signal peptide processing+++GO:0007040///lysosome organization+++GO:0007042///lysosomal lumen acidification+++GO:0007420///brain development+++GO:0007601///visual perception+++GO:0022008///neurogenesis+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0070085///glycosylation+++GO:1904426///positive regulation of GTP binding" 211323 211323 'Nrg1' mRNA 156 172 162 1.5 2.04 2.08 3.06 2.08 2.45 1.873333333 2.53 230 170 169 163.3333333 189.6666667 0.393367945 0.201052141 01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031594///neuromuscular junction+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0003712///transcription coregulator activity+++GO:0005102///signaling receptor binding+++GO:0005176///ErbB-2 class receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0030296///protein tyrosine kinase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0043125///ErbB-3 class receptor binding+++GO:0045499///chemorepellent activity "GO:0000165///MAPK cascade+++GO:0000902///cell morphogenesis+++GO:0001964///startle response+++GO:0003161///cardiac conduction system development+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0007420///brain development+++GO:0007422///peripheral nervous system development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008366///axon ensheathment+++GO:0010001///glial cell differentiation+++GO:0010625///positive regulation of Schwann cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016477///cell migration+++GO:0021781///glial cell fate commitment+++GO:0021842///chemorepulsion involved in interneuron migration from the subpallium to the cortex+++GO:0022008///neurogenesis+++GO:0022011///myelination in peripheral nervous system+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0031334///positive regulation of protein complex assembly+++GO:0031643///positive regulation of myelination+++GO:0032148///activation of protein kinase B activity+++GO:0035556///intracellular signal transduction+++GO:0038127///ERBB signaling pathway+++GO:0038129///ERBB3 signaling pathway+++GO:0038130///ERBB4 signaling pathway+++GO:0042060///wound healing+++GO:0042177///negative regulation of protein catabolic process+++GO:0043624///cellular protein complex disassembly+++GO:0045213///neurotransmitter receptor metabolic process+++GO:0045595///regulation of cell differentiation+++GO:0045773///positive regulation of axon extension+++GO:0045785///positive regulation of cell adhesion+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048513///animal organ development+++GO:0048663///neuron fate commitment+++GO:0048680///positive regulation of axon regeneration+++GO:0048709///oligodendrocyte differentiation+++GO:0048738///cardiac muscle tissue development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051048///negative regulation of secretion+++GO:0051155///positive regulation of striated muscle cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055007///cardiac muscle cell differentiation+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060379///cardiac muscle cell myoblast differentiation+++GO:0060956///endocardial cell differentiation+++GO:0060999///positive regulation of dendritic spine development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:0099560///synaptic membrane adhesion+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2000853///negative regulation of corticosterone secretion+++GO:2001223///negative regulation of neuron migration+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 211329 211329 'Ncoa7' mRNA 230.01 275 173 3.23 3.67 2.69 5.98 6.07 5.83 3.196666667 5.96 411.18 389 368 226.0033333 389.3933333 1.96E-06 0.779665137 04142///Lysosome GO:0005634///nucleus GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035257///nuclear hormone receptor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006979///response to oxidative stress+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1900408///negative regulation of cellular response to oxidative stress+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1903204///negative regulation of oxidative stress-induced neuron death 211347 211347 'Pank3' mRNA 772 710 703 5.53 5 5.34 4.82 3.86 4.44 5.29 4.373333333 775 607 692 728.3333333 691.3333333 0.521660753 -0.088704062 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004594///pantothenate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019842///vitamin binding+++GO:0042803///protein homodimerization activity+++GO:1905502///acetyl-CoA binding GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation 211378 211378 '6720489N17Rik' mRNA 112.03 124.7 99.53 1.9 2.25 1.77 1.46 1.35 1.83 1.973333333 1.546666667 89.42 84 112.9 112.0866667 95.44 0.415511414 -0.241481943 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 211383 211383 'Amer3' mRNA 157 136 125 1.94 1.65 1.64 0.21 0.1 0.2 1.743333333 0.17 20 9 18 139.3333333 15.66666667 1.19E-20 -3.164948807 GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008013///beta-catenin binding+++GO:0008289///lipid binding" GO:0016055///Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway 211389 211389 'Suox' mRNA 884 940 1026 21.08 22.08 25.96 17.96 18.86 17.14 23.04 17.98666667 866 888 800 950 851.3333333 0.151806304 -0.17324861 00920///Sulfur metabolism GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol GO:0008482///sulfite oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0030151///molybdenum ion binding+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding GO:0006790///sulfur compound metabolic process+++GO:0007584///response to nutrient 211401 211401 'Mtss1' mRNA 1571 1484 1338 17.68 17.01 16.66 14.34 13.33 16.16 17.11666667 14.61 1508 1274 1577 1464.333333 1453 0.863090843 -0.021914419 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0001701///in utero embryonic development+++GO:0007009///plasma membrane organization+++GO:0007015///actin filament organization+++GO:0007399///nervous system development+++GO:0007517///muscle organ development+++GO:0010960///magnesium ion homeostasis+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030282///bone mineralization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0034334///adherens junction maintenance+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0061333///renal tubule morphogenesis+++GO:0071498///cellular response to fluid shear stress+++GO:0072102///glomerulus morphogenesis+++GO:0072160///nephron tubule epithelial cell differentiation+++GO:0072170///metanephric tubule development+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis 211429 211429 'Pla2g4b' mRNA 205.37 170.51 181.19 2.88 2.35 2.69 1.8 1.58 1.63 2.64 1.67 147.81 126.64 129.75 185.69 134.7333333 0.022351717 -0.481248883 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04217///Necroptosis+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0031966///mitochondrial membrane "GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008970///phospholipase A1 activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0046475///glycerophospholipid catabolic process 211446 211446 'Exoc3' mRNA 1578 1797 1609 18.05 20.25 19.47 19.83 18.06 18.16 19.25666667 18.68333333 1998 1792 1778 1661.333333 1856 0.087302744 0.147831399 GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0030667///secretory granule membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0000149///SNARE binding GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0051601///exocyst localization 211468 211468 'Kcnh8' mRNA 441 487 394 4.72 5.09 4.51 0.53 0.52 0.68 4.773333333 0.576666667 57 57 67 440.6666667 60.33333333 3.09E-57 -2.877034435 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043066///negative regulation of apoptotic process+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 211480 211480 'Kcnj14' mRNA 9 19 17 0.19 0.37 0.36 0.2 0.3 0.3 0.306666667 0.266666667 11 17.1 16 15 14.7 0.962760552 -0.043523673 04725///Cholinergic synapse+++04921///Oxytocin signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 211482 211482 'Efhb' mRNA 272 363 320 5.53 7.33 6.96 0.75 0.5 0.54 6.606666667 0.596666667 42 28 29 318.3333333 33 9.54E-44 -3.284007021 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0061891///calcium ion sensor activity GO:0032091///negative regulation of protein binding+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:2001256///regulation of store-operated calcium entry 211484 211484 'Tsga10' mRNA 118.93 122.81 102.95 1.51 1.73 1.65 1.07 1.06 1.47 1.63 1.2 82.69 87.31 111 114.8966667 93.66666667 0.302388725 -0.29647018 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0043005///neuron projection+++GO:0097228///sperm principal piece GO:0005198///structural molecule activity+++GO:0005515///protein binding GO:0007283///spermatogenesis+++GO:0030031///cell projection assembly 211488 211488 'Ado' mRNA 1693.08 1805.65 1819.69 20.45 21.45 23.32 20.02 18.15 18.98 21.74 19.05 1907.58 1689.79 1751.2 1772.806667 1782.856667 0.957926008 -0.006212933 00430///Taurine and hypotaurine metabolism GO:0005739///mitochondrion "GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0047800///cysteamine dioxygenase activity+++GO:0051213///dioxygenase activity" 211499 211499 'Tmem87a' mRNA 1156.74 1201.14 1160.72 22.79 22.57 23.36 20.56 20.29 20.43 22.90666667 20.42666667 1246.3 1190.04 1205.74 1172.866667 1214.026667 0.740213982 0.037719776 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0003674///molecular_function "GO:0006810///transport+++GO:0042147///retrograde transport, endosome to Golgi" 211535 211535 'Ccdc114' mRNA 982 1033 921 22.12 21.87 21.27 3.8 3.78 2.84 21.75333333 3.473333333 183 196 148 978.6666667 175.6666667 1.50E-89 -2.488202835 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0036157///outer dynein arm+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0036158///outer dynein arm assembly 211548 211548 'Nomo1' mRNA 1394 1398 958 17.61 17.37 12.84 10.37 13 11.73 15.94 11.7 945 1157 1035 1250 1045.666667 0.049408806 -0.259378773 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0030246///carbohydrate binding+++GO:0043022///ribosome binding GO:0008150///biological_process 211550 211550 'Tifa' mRNA 733 733 653 17.38 17.71 16.92 23.83 23.33 22.89 17.33666667 23.35 1075 1043 1019 706.3333333 1045.666667 7.67E-10 0.555798398 05131///Shigellosis GO:0005737///cytoplasm GO:0005515///protein binding GO:0002376///immune system process+++GO:0002753///cytoplasmic pattern recognition receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0051260///protein homooligomerization 211556 211556 'Ap1ar' mRNA 1020 1185 776 23.51 26.79 19.22 6.33 6.82 6.96 23.17333333 6.703333333 313 327 332 993.6666667 324 5.19E-36 -1.620255868 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030133///transport vesicle GO:0019894///kinesin binding+++GO:0035650///AP-1 adaptor complex binding+++GO:0071933///Arp2/3 complex binding "GO:0001920///negative regulation of receptor recycling+++GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation+++GO:0034613///cellular protein localization+++GO:0048203///vesicle targeting, trans-Golgi to endosome+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:2000146///negative regulation of cell motility" 211577 211577 'Mrgprf' mRNA 59 50 38 1.68 1.42 1.14 7.5 5.77 6.89 1.413333333 6.72 304 226 269 49 266.3333333 5.10E-27 2.432678219 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 211578 211578 'Mrgprd' mRNA 3 3 3 0.05 0.05 0.06 0.11 0 0 0.053333333 0.036666667 7 0 0 3 2.333333333 0.863090843 -0.401862083 04614///Renin-angiotensin system GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 211586 211586 'Tfdp2' mRNA 1141 1215 1086 8.24 8.63 8.34 5.15 5.53 4.83 8.403333333 5.17 821 861 750 1147.333333 810.6666667 4.59E-08 -0.511300349 04110///Cell cycle GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0072686///mitotic spindle+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007507///heart development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle" 211612 211612 'Ptchd1' mRNA 9 6 1 0.08 0.05 0.01 0.12 0.27 0.16 0.046666667 0.183333333 17 37 22 5.333333333 25.33333333 0.003351879 2.26043627 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007614///short-term memory+++GO:0007616///long-term memory+++GO:0021794///thalamus development+++GO:0035176///social behavior+++GO:0050890///cognition+++GO:0098976///excitatory chemical synaptic transmission+++GO:0098977///inhibitory chemical synaptic transmission 211623 211623 'Plac9a' mRNA 89 79 74 17.99 16.03 15.89 24.6 27.04 22.63 16.63666667 24.75666667 138 147 122 80.66666667 135.6666667 0.002685844 0.740216141 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 211651 211651 'Fancd2' mRNA 108 77.93 112.92 1.12 0.76 1.19 0.86 0.81 0.92 1.023333333 0.863333333 97 90 100.8 99.61666667 95.93333333 0.863090843 -0.067186867 03460///Fanconi anemia pathway GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0070182///DNA polymerase binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0010332///response to gamma radiation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0034599///cellular response to oxidative stress+++GO:0036297///interstrand cross-link repair+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0048854///brain morphogenesis+++GO:0050727///regulation of inflammatory response+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0097150///neuronal stem cell population maintenance+++GO:1990918///double-strand break repair involved in meiotic recombination+++GO:2000348///regulation of CD40 signaling pathway 211652 211652 'Wwc1' mRNA 1241 1167 1185 16.36 15.1 16.6 8.05 7.2 7.22 16.02 7.49 702 610 611 1197.666667 641 4.56E-22 -0.915365592 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm "GO:0003713///transcription coactivator activity+++GO:0019900///kinase binding+++GO:0030674///protein binding, bridging+++GO:0060090///molecular adaptor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016477///cell migration+++GO:0035330///regulation of hippo signaling+++GO:0035331///negative regulation of hippo signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046621///negative regulation of organ growth" 211660 211660 'Cspp1' mRNA 411.04 461 489.01 5.44 6.26 6.88 4.25 3.88 3.75 6.193333333 3.96 368.02 342 325 453.6833333 345.0066667 0.004722753 -0.410479852 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005515///protein binding GO:0032467///positive regulation of cytokinesis+++GO:0051781///positive regulation of cell division 211666 211666 'Mgst2' mRNA 6 10 4 0.58 0.84 0.44 0.5 0.5 0.74 0.62 0.58 5 6 10 6.666666667 7 0.955045675 0.074125311 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004364///glutathione transferase activity+++GO:0004464///leukotriene-C4 synthase activity+++GO:0004602///glutathione peroxidase activity+++GO:0008047///enzyme activator activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0043295///glutathione binding GO:0006629///lipid metabolic process+++GO:0006691///leukotriene metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0019370///leukotriene biosynthetic process+++GO:0046466///membrane lipid catabolic process+++GO:0050790///regulation of catalytic activity+++GO:0098869///cellular oxidant detoxification 211673 211673 'Arfgef1' mRNA 1481 1404 1385 11.1 10.35 11.01 6.42 5.24 5.79 10.82 5.816666667 986 787 862 1423.333333 878.3333333 1.55E-14 -0.710057404 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0034237///protein kinase A regulatory subunit binding GO:0007030///Golgi organization+++GO:0010256///endomembrane system organization+++GO:0015031///protein transport+++GO:0030837///negative regulation of actin filament polymerization+++GO:0031175///neuron projection development+++GO:0032012///regulation of ARF protein signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0090284///positive regulation of protein glycosylation in Golgi+++GO:0090303///positive regulation of wound healing+++GO:2000114///regulation of establishment of cell polarity 211712 211712 'Pcdh9' mRNA 1079 1126 1049.73 9.34 9.61 9.7 6.45 6.2 5.66 9.55 6.103333333 839 797 719 1084.91 785 3.73E-07 -0.478314438 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0044291///cell-cell contact zone GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0030900///forebrain development 211739 211739 'Vstm2a' mRNA 22 12 21 0.34 0.18 0.33 0.2 0.28 0.41 0.283333333 0.296666667 15 21 30 18.33333333 22 0.749855753 0.248190065 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0010628///positive regulation of gene expression+++GO:0010884///positive regulation of lipid storage+++GO:0030154///cell differentiation+++GO:0070352///positive regulation of white fat cell proliferation+++GO:0071773///cellular response to BMP stimulus+++GO:0090336///positive regulation of brown fat cell differentiation 211770 211770 'Trib1' mRNA 668 701 584 8.95 9.24 8.3 12.49 12.12 11.61 8.83 12.07333333 1073 1017 966 651 1018.666667 2.42E-11 0.636457393 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004672///protein kinase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0055106///ubiquitin-protein transferase regulator activity GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007254///JNK cascade+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032496///response to lipopolysaccharide+++GO:0043405///regulation of MAP kinase activity+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity 211798 211798 'Mfsd9' mRNA 128 93 116 2.22 1.59 2.14 2.16 2.52 1.73 1.983333333 2.136666667 143 163 111 112.3333333 139 0.302591254 0.293705597 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 211896 211896 'Depdc7' mRNA 423 504 402 13.72 16.11 13.83 10.89 10.72 10.26 14.55333333 10.62333333 386 371 352 443 369.6666667 0.056383913 -0.27031051 GO:0005575///cellular_component GO:0003674///molecular_function GO:0035556///intracellular signal transduction 211914 211914 'Asap2' mRNA 862.77 835.56 411.65 7.23 6.94 3.55 2.41 2.32 2.86 5.906666667 2.53 337.39 312.48 387.38 703.3266667 345.75 0.002191315 -1.021158795 04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0043547///positive regulation of GTPase activity 211922 211922 'Dennd6a' mRNA 827.06 836.36 336.09 13.18 12.98 4.21 5.35 5.15 6.89 10.12333333 5.796666667 480.13 447.72 576.35 666.5033333 501.4 0.400659388 -0.403973397 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin 211924 211924 'Dsg1c' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 05150///Staphylococcus aureus infection GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0005509///calcium ion binding+++GO:0045295///gamma-catenin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0050821///protein stabilization+++GO:0098609///cell-cell adhesion 211936 211936 'Ccdc73' mRNA 16 18 28 0.22 0.24 0.41 0.1 0.06 0.17 0.29 0.11 8 5 14 20.66666667 9 0.09650579 -1.224147258 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 211945 211945 'Plekhh1' mRNA 438.9 442.98 238.24 3.7 3.58 2.13 1.1 1.02 1.27 3.136666667 1.13 149.44 138.75 167.74 373.3733333 151.9766667 3.72E-10 -1.299577957 GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 211948 211948 'Pde12' mRNA 443 420 442 6.82 6.36 7.22 9.53 9.3 8.79 6.8 9.206666667 712 679 636 435 675.6666667 6.66E-08 0.621886073 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000175///3'-5'-exoribonuclease activity+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0000958///mitochondrial mRNA catabolic process+++GO:0006397///mRNA processing+++GO:0035457///cellular response to interferon-alpha+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0045070///positive regulation of viral genome replication+++GO:0060548///negative regulation of cell death+++GO:0071346///cellular response to interferon-gamma+++GO:0071359///cellular response to dsRNA+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 211949 211949 'Spsb4' mRNA 258 274 213 6.51 6.81 5.7 3.97 3.98 4.58 6.34 4.176666667 181 177 202 248.3333333 186.6666667 0.021676234 -0.419286591 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex "GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0042752///regulation of circadian rhythm+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048511///rhythmic process+++GO:1902916///positive regulation of protein polyubiquitination 211961 211961 'Asxl3' mRNA 113 125 86 0.52 0.56 0.44 0.31 0.31 0.46 0.506666667 0.36 76 76 112 108 88 0.344990976 -0.299974787 GO:0005634///nucleus+++GO:0035517///PR-DUB complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009887///animal organ morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051055///negative regulation of lipid biosynthetic process" 211978 211978 'Zfyve26' mRNA 627 610 542 3.49 3.35 3.22 3.3 2.87 3.37 3.353333333 3.18 677 578 673 593 642.6666667 0.428575221 0.105328329 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0046872///metal ion binding GO:0000281///mitotic cytokinesis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division 211986 211986 'Tmem18' mRNA 772 886 782 14.35 16.21 15.42 13.91 13.1 14.08 15.32666667 13.69666667 861 792 844 813.3333333 832.3333333 0.863090843 0.022031799 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0016477///cell migration 212032 212032 'Hk3' mRNA 64 47 75 1.14 0.82 1.42 18.49 17.01 17.64 1.126666667 17.71333333 1220 1089 1121 62 1143.333333 8.66E-165 4.189325722 "00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++00524///Neomycin, kanamycin and gentamicin biosynthesis+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++04930///Type II diabetes mellitus+++04973///Carbohydrate digestion and absorption+++05131///Shigellosis+++05230///Central carbon metabolism in cancer" GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004340///glucokinase activity+++GO:0004396///hexokinase activity+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008865///fructokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019158///mannokinase activity+++GO:0019899///enzyme binding+++GO:0042562///hormone binding" GO:0001678///cellular glucose homeostasis+++GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0019318///hexose metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0051156///glucose 6-phosphate metabolic process+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death 212073 212073 'Syne3' mRNA 68 79 76 0.68 0.78 0.81 0.75 0.54 0.75 0.756666667 0.68 87 61 84 74.33333333 77.33333333 0.91165321 0.042214675 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0007097///nuclear migration+++GO:0008360///regulation of cell shape+++GO:0090150///establishment of protein localization to membrane 212090 212090 'Tmem60' mRNA 873 823 810 65.15 60.81 64.14 52.9 46.81 47.14 63.36666667 48.95 812 700 699 835.3333333 737 0.076835381 -0.193602418 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 212108 212108 'Rln3' mRNA 8 5 2 1.48 0.93 0.39 0 0.34 0.17 0.933333333 0.17 0 2 1 5 1 0.191655475 -2.305285812 04080///Neuroactive ligand-receptor interaction+++04926///Relaxin signaling pathway GO:0005576///extracellular region GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity GO:0007165///signal transduction 212111 212111 'Inpp5a' mRNA 140.76 138.91 106.92 2.83 2.74 2.3 2.33 2.14 2.52 2.623333333 2.33 133 118 138.68 128.8633333 129.8933333 0.975153954 0.010978956 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04910///Insulin signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0042995///cell projection "GO:0003824///catalytic activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042731///PH domain binding+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity" GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:1901215///negative regulation of neuron death 212114 212114 'Nhlrc3' mRNA 88 84 111 3.31 3.12 4.43 5.61 6.01 5.49 3.62 5.703333333 171 179 162 94.33333333 170.6666667 3.21E-04 0.838254934 GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 212123 212123 'Dcaf15' mRNA 137 172 129 3.21 3.95 3.16 3.62 3.78 4.28 3.44 3.893333333 176 181 202 146 186.3333333 0.114415684 0.344385277 GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0036094///small molecule binding+++GO:0046872///metal ion binding GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0016567///protein ubiquitination+++GO:0032814///regulation of natural killer cell activation 212124 212124 'Cfap46' mRNA 2346.99 2466 2197 17.57 18.25 17.48 1.1 1.08 1.33 17.76666667 1.17 180 172 215 2336.663333 189 1.75E-291 -3.638082447 GO:0003674///molecular_function GO:0035082///axoneme assembly+++GO:0060294///cilium movement involved in cell motility 212127 212127 'Proser1' mRNA 474 546 328 5.87 6.65 4.31 3.91 6.42 4.75 5.61 5.026666667 364 583 428 449.3333333 458.3333333 0.899897199 0.030839844 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 212139 212139 'Cc2d1a' mRNA 789 788 619 12.42 12.25 10.37 9.29 10.28 8.22 11.68 9.263333333 677 731 580 732 662.6666667 0.281028014 -0.150266106 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1905381///negative regulation of snRNA transcription by RNA polymerase II 212153 212153 'Ccdc191' mRNA 876 867 836 13.77 13.56 13.78 6.53 6.18 6.7 13.70333333 6.47 463 429 469 859.6666667 453.6666667 5.81E-20 -0.934109282 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 212163 212163 '8030462N17Rik' mRNA 715 707 766 7.71 7.46 8.77 5.71 5.83 5.98 7.98 5.84 615 608 615 729.3333333 612.6666667 0.021879946 -0.265646924 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process 212167 212167 'Gsap' mRNA 328.42 359.46 268.72 3.88 4.25 3.37 7.52 7.74 7.28 3.833333333 7.513333333 658.53 645.65 603.62 318.8666667 635.9333333 1.61E-15 0.989447806 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network GO:0001540///amyloid-beta binding GO:0030162///regulation of proteolysis+++GO:1902004///positive regulation of amyloid-beta formation 212168 212168 'Zswim4' mRNA 183 189 168 2.26 2.3 2.2 1.97 1.52 1.77 2.253333333 1.753333333 183 138 160 180 160.3333333 0.44226547 -0.179150116 GO:0031462///Cul2-RING ubiquitin ligase complex GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:1902667///regulation of axon guidance 212190 212190 'Ubxn10' mRNA 665 659 739 12.39 12.1 14.56 1.29 1.03 1.23 13.01666667 1.183333333 80 62 73 687.6666667 71.66666667 5.08E-89 -3.278862534 GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 212198 212198 'Wdr25' mRNA 274 293 298 5.97 5.97 6.3 4.05 3.67 4.6 6.08 4.106666667 213 205 210 288.3333333 209.3333333 0.004150616 -0.475406608 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 212276 212276 'Zfp748' mRNA 469 438 427 5.45 5 5.26 3.28 2.93 3.06 5.236666667 3.09 325 284 294 444.6666667 301 1.76E-05 -0.575279591 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 212281 212281 'Zfp729a' mRNA 428.35 494.16 422.22 3.39 3.8 3.46 3.57 2.91 3.23 3.55 3.236666667 507.3 401.46 443.19 448.2433333 450.65 0.986285049 -0.004467848 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 212285 212285 'Arap2' mRNA 629 630 502 4.63 4.52 3.79 3.38 2.79 3.3 4.313333333 3.156666667 546 443 518 587 502.3333333 0.07876152 -0.233775429 04144///Endocytosis GO:0005737///cytoplasm "GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0046872///metal ion binding" GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity 212307 212307 'Mapre2' mRNA 2375 2550 2574 31.89 33.65 36.71 27.75 28.56 28.22 34.08333333 28.17666667 2387 2394 2349 2499.666667 2376.666667 0.330953908 -0.086159408 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005925///focal adhesion+++GO:0015630///microtubule cytoskeleton+++GO:0035371///microtubule plus-end+++GO:0051233///spindle midzone GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0051010///microtubule plus-end binding GO:0007049///cell cycle+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0032014///positive regulation of ARF protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0051549///positive regulation of keratinocyte migration+++GO:0120183///positive regulation of focal adhesion disassembly+++GO:1904825///protein localization to microtubule plus-end 212326 212326 'Fam149a' mRNA 1605 1556 1254 23.31 21.42 17.98 3.69 6.45 5.79 20.90333333 5.31 318 507 455 1471.666667 426.6666667 9.76E-38 -1.789269278 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 212377 212377 'Mms22l' mRNA 22 26 20 0.29 0.32 0.28 0.76 1.28 1.02 0.296666667 1.02 69 120 92 22.66666667 93.66666667 2.50E-08 2.043046869 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0035101///FACT complex+++GO:0042555///MCM complex+++GO:0043596///nuclear replication fork GO:0003674///molecular_function GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing 212390 212390 'Klhl32' mRNA 642.98 661.96 603.78 6.07 6.4 5.79 2.19 2.41 2.29 6.086666667 2.296666667 247.28 239.6 253.92 636.24 246.9333333 3.75E-30 -1.377680783 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 212391 212391 'Lcor' mRNA 720 776 734 4.17 4.32 4.5 2.35 2.99 2.6 4.33 2.646666667 550 602 556 743.3333333 569.3333333 3.38E-04 -0.395799367 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding+++GO:0042826///histone deacetylase binding+++GO:1990226///histone methyltransferase binding+++GO:1990381///ubiquitin-specific protease binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus+++GO:1902466///positive regulation of histone H3-K27 trimethylation 212392 212392 'Ccdc110' mRNA 1 2 4 0.01 0.03 0.06 0 0 0 0.033333333 0 0 0 0 2.333333333 0 0.181200299 -3.701525005 GO:0005634///nucleus+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 212398 212398 'Frat2' mRNA 53 33 45 1.39 0.85 1.25 0.59 0.42 0.63 1.163333333 0.546666667 26 18 27 43.66666667 23.66666667 0.05496293 -0.900374545 04310///Wnt signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05200///Pathways in cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm GO:0003674///molecular_function GO:0016055///Wnt signaling pathway 212427 212427 'A730008H23Rik' mRNA 103.71 102.16 111.15 2.64 2.56 3 2.66 2.72 2.4 2.733333333 2.593333333 120.16 119.8 104.96 105.6733333 114.9733333 0.748435514 0.104120952 "GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion" GO:0003677///DNA binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0043254///regulation of protein complex assembly+++GO:0051101///regulation of DNA binding 212439 212439 'AA986860' mRNA 113 125 107 2.21 2.36 2.23 1.97 1.58 1.67 2.266666667 1.74 112 92 92 115 98.66666667 0.411265491 -0.23250108 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 212442 212442 'Lactb2' mRNA 423 372 414 12.72 10.94 13.13 15.19 15.32 13.88 12.26333333 14.79666667 582 575 520 403 559 4.11E-04 0.458294055 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 212448 212448 '9330159F19Rik' mRNA 529.22 446 472 5.18 4.31 4.96 1.87 2.1 2.23 4.816666667 2.066666667 224 241 254 482.4066667 239.6666667 8.45E-13 -1.020533227 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 212483 212483 'Fam193b' mRNA 1027 994 877 18.12 17.42 18.39 13.31 12.93 11.6 17.97666667 12.61333333 756 721 689 966 722 6.69E-06 -0.429920558 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0008150///biological_process 212503 212503 'Paox' mRNA 827.81 791.13 746.03 11.57 10.8 11.81 30.88 33.94 34.18 11.39333333 33 1519.03 1597.25 1623.82 788.3233333 1580.033333 6.24E-32 0.993222576 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix "GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity+++GO:0052899///N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity+++GO:0052901///spermine:oxygen oxidoreductase (spermidine-forming) activity+++GO:0052902///spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity+++GO:0052903///N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity+++GO:0052904///N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity" GO:0006598///polyamine catabolic process+++GO:0009446///putrescine biosynthetic process+++GO:0009447///putrescine catabolic process+++GO:0046203///spermidine catabolic process+++GO:0046208///spermine catabolic process+++GO:1901307///positive regulation of spermidine biosynthetic process 212508 212508 'Mtg1' mRNA 587 525 537 23.53 21.16 23.47 15.08 16.81 16.17 22.72 16.02 431 465 450 549.6666667 448.6666667 0.017025959 -0.304209105 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005761///mitochondrial ribosome+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006417///regulation of translation+++GO:0044065///regulation of respiratory system process+++GO:0070129///regulation of mitochondrial translation 212514 212514 'Spice1' mRNA 408 415 410 5.2 5.1 5.56 2.87 2.6 3.02 5.286666667 2.83 259 228 263 411 250 2.44E-07 -0.730202322 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0046599///regulation of centriole replication+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0090307///mitotic spindle assembly 212516 212516 'Efcab12' mRNA 386 403 405 8.42 8.65 9.37 2.29 2.39 2.11 8.813333333 2.263333333 121 123 108 398 117.3333333 6.62E-28 -1.775187812 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 212517 212517 'Cfap44' mRNA 901 959 900 7 7.33 7.41 0.65 0.61 0.66 7.246666667 0.64 95 86 96 920 92.33333333 2.20E-132 -3.328730642 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0008233///peptidase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006508///proteolysis+++GO:0007288///sperm axoneme assembly+++GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0060285///cilium-dependent cell motility 212518 212518 'Sprn' mRNA 44 32 39 0.76 0.55 0.72 0.6 0.65 0.64 0.676666667 0.63 40 42 41 38.33333333 41 0.865506706 0.0838742 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031982///vesicle GO:0003676///nucleic acid binding GO:0006606///protein import into nucleus 212528 212528 'Trmt1' mRNA 826 757 730 20.06 18.1 18.98 18.22 17.66 18.66 19.04666667 18.18 836 801 842 771 826.3333333 0.449579341 0.08888041 GO:0005634///nucleus GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0004809///tRNA (guanine-N2-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0002940///tRNA N2-guanine methylation+++GO:0008033///tRNA processing+++GO:0032259///methylation 212531 212531 'Sh3bgrl2' mRNA 133 132 116 2.07 2.02 1.91 4.75 4.89 5.27 2 4.97 352 354 378 127 361.3333333 1.75E-20 1.498980392 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0008150///biological_process 212539 212539 'Gm266' mRNA 2344 2370 1875 118.2 118.02 100.32 25.79 27.39 28.49 112.18 27.22333333 587 608 627 2196.333333 607.3333333 1.42E-97 -1.861289444 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0007165///signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0032486///Rap protein signal transduction 212541 212541 'Rho' mRNA 34 41 30 0.33 0.39 0.25 0.29 0.11 0.23 0.323333333 0.21 36 14 28 35 26 0.436816338 -0.442174643 04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0042622///photoreceptor outer segment membrane+++GO:0042995///cell projection+++GO:0060342///photoreceptor inner segment membrane+++GO:0097225///sperm midpiece+++GO:0097381///photoreceptor disc membrane+++GO:1990913///sperm head plasma membrane GO:0004930///G protein-coupled receptor activity+++GO:0005502///11-cis retinal binding+++GO:0005515///protein binding+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity+++GO:0016918///retinal binding+++GO:0030507///spectrin binding+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009416///response to light stimulus+++GO:0009583///detection of light stimulus+++GO:0009585///red, far-red light phototransduction+++GO:0016038///absorption of visible light+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0018298///protein-chromophore linkage+++GO:0043052///thermotaxis+++GO:0045494///photoreceptor cell maintenance+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus+++GO:0050960///detection of temperature stimulus involved in thermoception+++GO:0060041///retina development in camera-type eye+++GO:0071482///cellular response to light stimulus" 212547 212547 'Nepro' mRNA 556.21 584.96 561.88 5.55 5.74 5.91 4.24 4.27 3.85 5.733333333 4.12 475.71 474.87 431.48 567.6833333 460.6866667 0.01002478 -0.313746711 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0045665///negative regulation of neuron differentiation+++GO:0045747///positive regulation of Notch signaling pathway 212555 212555 'Slc66a1' mRNA 512.47 469.42 527.21 6.09 5.62 7.14 19.39 18.63 19.61 6.283333333 19.21 924.34 864.6 915.98 503.0333333 901.64 1.63E-14 0.827459613 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006865///amino acid transport+++GO:0015809///arginine transport+++GO:0015819///lysine transport+++GO:0080144///amino acid homeostasis+++GO:1903401///L-lysine transmembrane transport+++GO:1903826///arginine transmembrane transport+++GO:1990822///basic amino acid transmembrane transport 212569 212569 'Zfp273' mRNA 118.24 108.24 131.73 2.86 2.58 3.38 1.5 1.87 1.24 2.94 1.536666667 71.46 86.95 57.35 119.4033333 71.92 0.00752206 -0.753283656 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 212627 212627 'Prpsap2' mRNA 594 681 618 18.79 21.32 20.62 14.43 16.71 14.17 20.24333333 15.10333333 524 589 505 631 539.3333333 0.064911755 -0.236927544 GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0042802///identical protein binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0009165///nucleotide biosynthetic process+++GO:0060348///bone development 212632 212632 'Iffo2' mRNA 400.55 372 307.17 3.7 3.27 2.88 2.08 1.93 2.08 3.283333333 2.03 265.06 241.39 257.39 359.9066667 254.6133333 8.38E-04 -0.508393414 GO:0005575///cellular_component+++GO:0005882///intermediate filament GO:0003674///molecular_function GO:0008150///biological_process 212647 212647 'Aldh4a1' mRNA 1039 1108.02 1075 16.87 17.7 18.51 14.29 12.77 12.5 17.69333333 13.18666667 1012 884 859.07 1074.006667 918.3566667 0.017003146 -0.239510085 "00250///Alanine, aspartate and glutamate metabolism+++00330///Arginine and proline metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol "GO:0003842///1-pyrroline-5-carboxylate dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004777///succinate-semialdehyde dehydrogenase (NAD+) activity+++GO:0009013///succinate-semialdehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0031406///carboxylic acid binding+++GO:0042802///identical protein binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity+++GO:0051287///NAD binding" GO:0006105///succinate metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006560///proline metabolic process+++GO:0007417///central nervous system development+++GO:0009448///gamma-aminobutyric acid metabolic process+++GO:0009450///gamma-aminobutyric acid catabolic process+++GO:0009791///post-embryonic development+++GO:0010133///proline catabolic process to glutamate+++GO:0042135///neurotransmitter catabolic process 212670 212670 'Catsper2' mRNA 247.93 235.22 183.62 4.67 4.53 3.44 1.43 1.25 1.58 4.213333333 1.42 80.04 80.16 87.2 222.2566667 82.46666667 5.78E-12 -1.435424823 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0036128///CatSper complex+++GO:0042995///cell projection GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005262///calcium channel activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0048240///sperm capacitation+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 212679 212679 'Mars2' mRNA 155 152 94 2.96 2.86 1.91 3.29 3.08 3.23 2.576666667 3.2 198 181 188 133.6666667 189 0.029111746 0.495934151 00450///Selenocompound metabolism+++00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004825///methionine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006431///methionyl-tRNA aminoacylation 212706 212706 'N4bp3' mRNA 164 172 149 3.81 4.02 3.77 5.8 5.61 5.55 3.866666667 5.653333333 278 262 267 161.6666667 269 1.87E-05 0.724352994 GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008150///biological_process 212712 212712 'Satb2' mRNA 7 14 9 0.07 0.14 0.1 0.07 0.17 0.06 0.103333333 0.1 9 19 7 10 11.66666667 0.846109779 0.220744266 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016363///nuclear matrix "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0002076///osteoblast development+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009880///embryonic pattern specification+++GO:0010468///regulation of gene expression+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0051216///cartilage development+++GO:0060021///roof of mouth development+++GO:0071310///cellular response to organic substance 212728 212728 'Tarbp1' mRNA 90 62 42 0.95 0.64 0.47 0.39 0.26 0.57 0.686666667 0.406666667 43 28 60 64.66666667 43.66666667 0.197035827 -0.569771299 GO:0003723///RNA binding+++GO:0008173///RNA methyltransferase activity+++GO:0016423///tRNA (guanine) methyltransferase activity GO:0006396///RNA processing+++GO:0030488///tRNA methylation 212733 212733 'Bicdl2' mRNA 182 205 203 5.35 5.94 6.32 5.89 6.34 5.37 5.87 5.866666667 231 242 204 196.6666667 225.6666667 0.377446957 0.185655871 GO:0005737///cytoplasm GO:0031267///small GTPase binding GO:0047496///vesicle transport along microtubule+++GO:0055107///Golgi to secretory granule transport 212772 212772 'Arl14ep' mRNA 1154 1092 1262 19.05 17.73 22.17 15.63 16.35 15.85 19.65 15.94333333 1090 1118 1070 1169.333333 1092.666667 0.34177867 -0.113117608 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 212862 212862 'Chpt1' mRNA 4218.29 4365.16 3740.12 90.51 88.75 80.54 65.27 56.74 64.38 86.6 62.13 3814 3138.23 3631.4 4107.856667 3527.876667 0.001795915 -0.230333014 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++05231///Choline metabolism in cancer GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0006663///platelet activating factor biosynthetic process+++GO:0008654///phospholipid biosynthetic process 212880 212880 'Ddx46' mRNA 1623 1698 1597 15.09 15.52 15.75 12.54 13.31 13.26 15.45333333 13.03666667 1553 1611 1591 1639.333333 1585 0.530186199 -0.059661572 03040///Spliceosome GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0015030///Cajal body+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 212892 212892 'Rsph4a' mRNA 695 736 794 10.33 10.76 12.52 0.8 1 1.03 11.20333333 0.943333333 62 76 77 741.6666667 71.66666667 2.24E-96 -3.385464961 GO:0001534///radial spoke+++GO:0001535///radial spoke head+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection GO:0003674///molecular_function+++GO:0005515///protein binding GO:0003341///cilium movement+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility 212898 212898 'Dse' mRNA 883 842 788 12.08 11.39 11.69 19.29 18.77 21.92 11.72 19.99333333 1522 1513 1662 837.6666667 1565.666667 1.13E-25 0.892000204 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0016853///isomerase activity+++GO:0046872///metal ion binding+++GO:0047757///chondroitin-glucuronate 5-epimerase activity GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030204///chondroitin sulfate metabolic process+++GO:0030205///dermatan sulfate metabolic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0030208///dermatan sulfate biosynthetic process 212919 212919 'Kctd7' mRNA 539 466 439.8 7.43 6.14 6.33 3.98 3.48 2.64 6.633333333 3.366666667 336.07 282 213 481.6 277.0233333 7.03E-07 -0.809264713 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0042802///identical protein binding GO:0030007///cellular potassium ion homeostasis+++GO:0032411///positive regulation of transporter activity+++GO:0051260///protein homooligomerization+++GO:0060081///membrane hyperpolarization+++GO:0090461///glutamate homeostasis 212933 212933 'Pm20d1' mRNA 126 135 112 2.08 2.04 1.99 2.54 3.05 2.67 2.036666667 2.753333333 185 218 187 124.3333333 196.6666667 0.001457183 0.65371687 GO:0005576///extracellular region+++GO:0005615///extracellular space "GO:0004046///aminoacylase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0016829///lyase activity+++GO:0046872///metal ion binding" GO:0006508///proteolysis+++GO:0006520///cellular amino acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006807///nitrogen compound metabolic process+++GO:0022904///respiratory electron transport chain+++GO:0043604///amide biosynthetic process+++GO:0043605///cellular amide catabolic process+++GO:0044255///cellular lipid metabolic process+++GO:0097009///energy homeostasis+++GO:1901215///negative regulation of neuron death+++GO:1990845///adaptive thermogenesis+++GO:2000275///regulation of oxidative phosphorylation uncoupler activity 212937 212937 'Tifab' mRNA 65 87 66 0.97 1.29 1.05 9.34 10.14 9.95 1.103333333 9.81 742 773 761 72.66666667 758.6666667 5.28E-107 3.375072442 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007356///thorax and anterior abdomen determination+++GO:0021559///trigeminal nerve development+++GO:0021650///vestibulocochlear nerve formation+++GO:0030432///peristalsis+++GO:0031223///auditory behavior+++GO:0035112///genitalia morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0048634///regulation of muscle organ development+++GO:0048806///genitalia development+++GO:0048839///inner ear development+++GO:0050885///neuromuscular process controlling balance+++GO:0071626///mastication+++GO:0090102///cochlea development+++GO:0090103///cochlea morphogenesis+++GO:0097094///craniofacial suture morphogenesis+++GO:0098583///learned vocalization behavior+++GO:1901078///negative regulation of relaxation of muscle+++GO:1905747///negative regulation of saliva secretion+++GO:1905748///hard palate morphogenesis 212943 212943 'Tent5a' mRNA 373 383 369 3.63 3.68 3.82 8.54 7.18 8.07 3.71 7.93 1007 828 923 375 919.3333333 7.40E-32 1.280474897 GO:0005575///cellular_component GO:1990817///RNA adenylyltransferase activity GO:0009617///response to bacterium+++GO:0048255///mRNA stabilization 212974 212974 'Pgghg' mRNA 734 684 694 12.82 11.88 12.86 14.53 13.61 15.35 12.52 14.49666667 957 876 974 704 935.6666667 6.76E-05 0.397811442 GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0047402///protein-glucosylgalactosylhydroxylysine glucosidase activity" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process 212980 212980 'Slc45a3' mRNA 164 207 211 2.75 3.41 3.78 4.43 3.92 3.77 3.313333333 4.04 305 263 250 194 272.6666667 0.011632048 0.475187127 05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008506///sucrose:proton symporter activity+++GO:0022857///transmembrane transporter activity GO:0010907///positive regulation of glucose metabolic process+++GO:0015770///sucrose transport+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0055085///transmembrane transport 212986 212986 'Scfd2' mRNA 189 248 243 3.44 4.57 4.41 4.96 3.7 5.04 4.14 4.566666667 329 246 344 226.6666667 306.3333333 0.032196013 0.418654425 GO:0005886///plasma membrane+++GO:0030141///secretory granule GO:0019905///syntaxin binding GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 212989 212989 'Best2' mRNA 1 0 3 0.03 0 0.1 0 0 0.06 0.043333333 0.02 0 0 2 1.333333333 0.666666667 0.773801597 -1.050957329 04970///Salivary secretion GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005254///chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007608///sensory perception of smell+++GO:0051899///membrane depolarization+++GO:1902476///chloride transmembrane transport 212996 212996 'Galnt17' mRNA 58 66 70 0.78 0.89 1.01 0.45 0.56 0.61 0.893333333 0.54 39 47 49 64.66666667 45 0.145309577 -0.536128588 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008150///biological_process 212998 212998 'BC016579' mRNA 54 86 48 1.37 2.17 1.31 1.58 1.26 1.48 1.616666667 1.44 71 57 64 62.66666667 64 0.957154037 0.025199545 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 212999 212999 'Tnpo2' mRNA 1047 958 713 11.45 10.25 8.22 11.33 10.07 10.34 9.973333333 10.58 1190 1035 1051 906 1092 0.029416765 0.262836514 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0031267///small GTPase binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0051148///negative regulation of muscle cell differentiation 213002 213002 'Ifitm6' mRNA 13 13 18 1.94 1.94 2.85 13.5 12.29 11.57 2.243333333 12.45333333 103 91 85 14.66666667 93 1.99E-12 2.647649377 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 213006 213006 'Mfsd4a' mRNA 2082.62 1906.23 1714.67 29.38 26.61 24.6 16.97 17.44 17.43 26.86333333 17.28 1713.5 1645.83 1729.63 1901.173333 1696.32 0.034475698 -0.174186352 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 213011 213011 'Zfp583' mRNA 263.53 223.66 243.09 2.15 1.67 2.21 2.22 2.13 2.05 2.01 2.133333333 414.68 386.11 377.77 243.4266667 392.8533333 4.46E-06 0.677850264 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 213012 213012 'Abhd10' mRNA 517 554 458 14.86 14.71 13.66 12.6 14.01 14.13 14.41 13.58 448 510 485 509.6666667 481 0.555574003 -0.091233902 GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0102390///mycophenolic acid acyl-glucuronide esterase activity" GO:0002084///protein depalmitoylation+++GO:0019391///glucuronoside catabolic process 213019 213019 'Pdlim2' mRNA 629 677 666 24.54 25.76 26.63 42.53 40.57 40.89 25.64333333 41.33 1276 1191 1206 657.3333333 1224.333333 3.69E-22 0.884272539 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0030018///Z disc+++GO:0030864///cortical actin cytoskeleton+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0031005///filamin binding+++GO:0032036///myosin heavy chain binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding+++GO:0051393///alpha-actinin binding GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0061061///muscle structure development 213027 213027 'Evi5l' mRNA 925 914 864 13.28 12.95 13.28 8.7 9.06 9.44 13.17 9.066666667 701 710 739 901 716.6666667 4.55E-04 -0.341053841 GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity+++GO:1902018///negative regulation of cilium assembly 213043 213043 'Aox2' mRNA 15 17 31 0.19 0.2 0.41 0.08 0.08 0.13 0.266666667 0.096666667 7 7 11 21 8.333333333 0.061010725 -1.360659473 "00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00380///Tryptophan metabolism+++00750///Vitamin B6 metabolism+++00760///Nicotinate and nicotinamide metabolism+++00830///Retinol metabolism+++00982///Drug metabolism - cytochrome P450+++04630///JAK-STAT signaling pathway" GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004031///aldehyde oxidase activity+++GO:0005506///iron ion binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050250///retinal oxidase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0071949///FAD binding+++GO:0102797///geranial:oxygen oxidoreductase activity+++GO:0102798///heptaldehyde:oxygen oxidoreductase activity" GO:0017144///drug metabolic process 213053 213053 'Slc39a14' mRNA 283 284 258 2.19 2.13 2 4.36 3.8 4.31 2.106666667 4.156666667 591 532 610 275 577.6666667 2.21E-17 1.059829421 04216///Ferroptosis+++05010///Alzheimer disease+++05012///Parkinson disease GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0005385///zinc ion transmembrane transporter activity+++GO:0015086///cadmium ion transmembrane transporter activity+++GO:0015093///ferrous iron transmembrane transporter activity+++GO:0015296///anion:cation symporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0002062///chondrocyte differentiation+++GO:0006094///gluconeogenesis+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0008286///insulin receptor signaling pathway+++GO:0010817///regulation of hormone levels+++GO:0015698///inorganic anion transport+++GO:0030001///metal ion transport+++GO:0032869///cellular response to insulin stimulus+++GO:0033212///iron assimilation+++GO:0034755///iron ion transmembrane transport+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0055071///manganese ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070574///cadmium ion transmembrane transport+++GO:0071333///cellular response to glucose stimulus+++GO:0071421///manganese ion transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0071578///zinc ion import across plasma membrane+++GO:0098739///import across plasma membrane 213054 213054 'Gabpb2' mRNA 1077.31 1107.65 1006.72 7.91 7.87 8.04 6.36 5.91 6.14 7.94 6.136666667 1018.34 920.95 945.6 1063.893333 961.63 0.095068159 -0.157327859 GO:0005634///nucleus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0042802///identical protein binding GO:0045944///positive regulation of transcription by RNA polymerase II 213056 213056 'Fam126b' mRNA 774 855 758 5.4 5.87 5.51 3.73 3.02 3.13 5.593333333 3.293333333 628 501 532 795.6666667 553.6666667 1.49E-06 -0.535580245 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 213068 213068 'Tmem71' mRNA 34 22 32 0.64 0.41 0.64 2.22 2.14 2.28 0.563333333 2.213333333 136 128 135 29.33333333 133 2.91E-13 2.165906809 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 213081 213081 'Wdr19' mRNA 745 787 726 8.55 8.95 8.71 2.62 2.52 2.43 8.736666667 2.523333333 251 244 235 752.6666667 243.3333333 3.21E-45 -1.640435845 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030991///intraciliary transport particle A+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection+++GO:0097730///non-motile cilium GO:0003674///molecular_function GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0007224///smoothened signaling pathway+++GO:0008406///gonad development+++GO:0030030///cell projection organization+++GO:0030326///embryonic limb morphogenesis+++GO:0031076///embryonic camera-type eye development+++GO:0035721///intraciliary retrograde transport+++GO:0042471///ear morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0050877///nervous system process+++GO:0055123///digestive system development+++GO:0060271///cilium assembly+++GO:0060830///ciliary receptor clustering involved in smoothened signaling pathway+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0061055///myotome development+++GO:0061512///protein localization to cilium+++GO:0065003///protein-containing complex assembly+++GO:1903441///protein localization to ciliary membrane 213084 213084 'Cdkl3' mRNA 337 332 312 5.42 5.29 5.29 3.27 2.32 2.51 5.333333333 2.7 191 136 158 327 161.6666667 1.09E-09 -1.029682412 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030517///negative regulation of axon extension+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051726///regulation of cell cycle+++GO:0097484///dendrite extension 213109 213109 'Phf3' mRNA 896 849 683 6.4 5.99 5.47 5.21 4.29 4.98 5.953333333 4.826666667 843 665 773 809.3333333 760.3333333 0.477818196 -0.099208241 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0008150///biological_process" 213119 213119 'Itga10' mRNA 97 116 93 1.03 1.21 1.05 1.61 1.25 1.93 1.096666667 1.596666667 175 133 203 102 170.3333333 0.002247778 0.729314663 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0008305///integrin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034680///integrin alpha10-beta1 complex GO:0046872///metal ion binding+++GO:0098639///collagen binding involved in cell-matrix adhesion GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway 213121 213121 'Ankrd35' mRNA 63 70 84 0.88 0.97 1.28 1.51 1.33 1.39 1.043333333 1.41 121 105 106 72.33333333 110.6666667 0.034625458 0.595628112 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 213171 213171 'Prss27' mRNA 8 1 1 0.43 0.05 0.06 0.05 0.34 0.73 0.18 0.373333333 1 7 15 3.333333333 7.666666667 0.409731815 1.214599309 GO:0005576///extracellular region+++GO:0005886///plasma membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 213208 213208 'Il20rb' mRNA 25 25 22 0.56 0.55 0.53 1.92 1.82 1.52 0.546666667 1.753333333 98 91 75 24 88 6.23E-08 1.863497572 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04630///JAK-STAT signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0042015///interleukin-20 binding GO:0001808///negative regulation of type IV hypersensitivity+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0002765///immune response-inhibiting signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050863///regulation of T cell activation 213211 213211 'Rnf26' mRNA 443 416 203 10.96 10.14 5.33 6.54 6.3 8.25 8.81 7.03 304 286 371 354 320.3333333 0.612251631 -0.141005672 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007032///endosome organization+++GO:0016567///protein ubiquitination+++GO:0032479///regulation of type I interferon production+++GO:0050687///negative regulation of defense response to virus+++GO:0070979///protein K11-linked ubiquitination+++GO:1905719///protein localization to perinuclear region of cytoplasm 213233 213233 'Tapbpl' mRNA 886.75 796.76 860.3 24.09 21.3 24.77 28.38 29.25 29.76 23.38666667 29.13 1203.15 1209.62 1222.24 847.9366667 1211.67 9.79E-08 0.502570923 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0023024///MHC class I protein complex binding GO:0002376///immune system process+++GO:0002502///peptide antigen assembly with MHC class I protein complex+++GO:0002590///negative regulation of antigen processing and presentation of peptide antigen via MHC class I 213234 213234 'Zbbx' mRNA 218.14 246.78 260.59 4.86 5.4 6.11 0.44 0.58 0.58 5.456666667 0.533333333 21.39 30.04 25.4 241.8366667 25.61 1.76E-35 -3.265490401 GO:0031514///motile cilium GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0003341///cilium movement 213236 213236 'Dnd1' mRNA 15 26 20 0.61 1.03 0.86 1.34 1.33 1.02 0.833333333 1.23 38 37 28 20.33333333 34.33333333 0.158626287 0.744740738 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0035198///miRNA binding GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0048255///mRNA stabilization+++GO:0060965///negative regulation of gene silencing by miRNA+++GO:0061158///3'-UTR-mediated mRNA destabilization 213248 213248 'Wdr49' mRNA 10 12 3 0.12 0.18 0.04 0.03 0.03 0.03 0.113333333 0.03 2 2 2 8.333333333 2 0.105840002 -2.048945337 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 213262 213262 'Fstl5' mRNA 0 0 2 0 0 0.03 0 0 0 0.01 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005576///extracellular region GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0030154///cell differentiation 213272 213272 'Txndc2' mRNA 4 3 0 0.13 0.1 0 0.03 0.02 0.08 0.076666667 0.043333333 1 1 3 2.333333333 1.666666667 0.863090843 -0.464626127 GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0036126///sperm flagellum GO:0003756///protein disulfide isomerase activity+++GO:0004791///thioredoxin-disulfide reductase activity GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0034614///cellular response to reactive oxygen species+++GO:0098869///cellular oxidant detoxification 21331 21331 'T2' mRNA 2 0 1 0.02 0 0.03 0.01 0.03 0 0.016666667 0.013333333 1 1 0 1 0.666666667 0.863090843 -0.605501595 GO:0005575///cellular_component GO:0003674///molecular_function GO:0014028///notochord formation 213311 213311 'Fbxl21' mRNA 103 87 76 2.33 2.31 2.2 2.56 3.15 2.19 2.28 2.633333333 72 85 78 88.66666667 78.33333333 0.591836354 -0.185821978 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle 213326 213326 'Scyl2' mRNA 409 405 411 5.55 4.94 5.41 4.69 4.61 4.76 5.3 4.686666667 453 432 457 408.3333333 447.3333333 0.427695243 0.11883649 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle GO:0004672///protein kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0002092///positive regulation of receptor internalization+++GO:0006468///protein phosphorylation+++GO:0007420///brain development+++GO:0008333///endosome to lysosome transport+++GO:0021860///pyramidal neuron development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:2000370///positive regulation of clathrin-dependent endocytosis 213332 213332 'Mfsd4b4' mRNA 251 249.99 170 3.4 3.42 2.64 1.96 2.52 1.96 3.153333333 2.146666667 154 198 159.98 223.6633333 170.66 0.071829803 -0.39326375 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 21334 21334 'Tac2' mRNA 1 0 1 0.11 0 0.11 0 0.19 0 0.073333333 0.063333333 0 2 0 0.666666667 0.666666667 0.998591786 -0.011426751 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0031836///neuromedin K receptor binding+++GO:0031837///substance K receptor binding GO:0007217///tachykinin receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0045777///positive regulation of blood pressure+++GO:1902093///positive regulation of flagellated sperm motility 21335 21335 'Tacc3' mRNA 159.54 164.37 127.5 3.63 3.8 3.07 14.23 13.22 14.4 3.5 13.95 666.41 617 673.62 150.47 652.3433333 1.12E-54 2.111234143 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0000226///microtubule cytoskeleton organization+++GO:0001666///response to hypoxia+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0022027///interkinetic nuclear migration+++GO:0030097///hemopoiesis+++GO:0030953///astral microtubule organization+++GO:0032886///regulation of microtubule-based process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0060236///regulation of mitotic spindle organization+++GO:1902850///microtubule cytoskeleton organization involved in mitosis 213350 213350 'Gatd1' mRNA 1329 1405 1288 52.57 54.86 54.1 41.96 40.34 42.3 53.84333333 41.53333333 1216 1142 1187 1340.666667 1181.666667 0.021370705 -0.193495656 GO:0005576///extracellular region 21336 21336 'Tacr1' mRNA 1 4.99 9 0.01 0.05 0.1 0.02 0.03 0 0.053333333 0.016666667 2 3 0 4.996666667 1.666666667 0.394227551 -1.525935432 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0036126///sperm flagellum+++GO:0044297///cell body+++GO:0061827///sperm head+++GO:0071944///cell periphery+++GO:0097225///sperm midpiece GO:0004757///sepiapterin reductase activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004995///tachykinin receptor activity+++GO:0016491///oxidoreductase activity+++GO:0016496///substance P receptor activity+++GO:0042803///protein homodimerization activity "GO:0002118///aggressive behavior+++GO:0002687///positive regulation of leukocyte migration+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0006558///L-phenylalanine metabolic process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007217///tachykinin receptor signaling pathway+++GO:0007611///learning or memory+++GO:0007616///long-term memory+++GO:0008217///regulation of blood pressure+++GO:0008306///associative learning+++GO:0009408///response to heat+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010193///response to ozone+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010996///response to auditory stimulus+++GO:0014070///response to organic cyclic compound+++GO:0014910///regulation of smooth muscle cell migration+++GO:0019233///sensory perception of pain+++GO:0019889///pteridine metabolic process+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0035094///response to nicotine+++GO:0035106///operant conditioning+++GO:0035815///positive regulation of renal sodium excretion+++GO:0040014///regulation of multicellular organism growth+++GO:0042415///norepinephrine metabolic process+++GO:0042417///dopamine metabolic process+++GO:0042428///serotonin metabolic process+++GO:0042713///sperm ejaculation+++GO:0042755///eating behavior+++GO:0043117///positive regulation of vascular permeability+++GO:0045471///response to ethanol+++GO:0045760///positive regulation of action potential+++GO:0045777///positive regulation of blood pressure+++GO:0045778///positive regulation of ossification+++GO:0045907///positive regulation of vasoconstriction+++GO:0046146///tetrahydrobiopterin metabolic process+++GO:0046878///positive regulation of saliva secretion+++GO:0046887///positive regulation of hormone secretion+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050882///voluntary musculoskeletal movement+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0070472///regulation of uterine smooth muscle contraction+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility" 21337 21337 'Tacr2' mRNA 3 0 1 0.07 0 0.03 0.06 0.07 0.02 0.033333333 0.05 3 3 1 1.333333333 2.333333333 0.749890709 0.794970157 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036126///sperm flagellum+++GO:0061827///sperm head+++GO:0097225///sperm midpiece GO:0004930///G protein-coupled receptor activity+++GO:0004995///tachykinin receptor activity+++GO:0016497///substance K receptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007217///tachykinin receptor signaling pathway+++GO:0014057///positive regulation of acetylcholine secretion, neurotransmission+++GO:0014827///intestine smooth muscle contraction+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0035106///operant conditioning+++GO:0043117///positive regulation of vascular permeability+++GO:0043270///positive regulation of ion transport+++GO:0051602///response to electrical stimulus+++GO:0070459///prolactin secretion+++GO:0070472///regulation of uterine smooth muscle contraction+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility" 21338 21338 'Tacr3' mRNA 724 723 689 10.42 10.23 10.52 9.85 8.52 9.23 10.39 9.2 788 666 715 712 723 0.946902141 0.009453174 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0097225///sperm midpiece GO:0004930///G protein-coupled receptor activity+++GO:0004995///tachykinin receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007217///tachykinin receptor signaling pathway+++GO:0007568///aging+++GO:0010460///positive regulation of heart rate+++GO:0032355///response to estradiol+++GO:0042053///regulation of dopamine metabolic process+++GO:0042220///response to cocaine+++GO:0042538///hyperosmotic salinity response+++GO:0043278///response to morphine+++GO:0045777///positive regulation of blood pressure+++GO:0060259///regulation of feeding behavior+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility 213389 213389 'Prdm9' mRNA 119.66 127 145 1.63 1.75 2.15 1.06 1.04 1.28 1.843333333 1.126666667 98 81 105 130.5533333 94.66666667 0.067303262 -0.478109951 00310///Lysine degradation GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0010844///recombination hotspot binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0006311///meiotic gene conversion+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0007292///female gamete generation+++GO:0010468///regulation of gene expression+++GO:0010845///positive regulation of reciprocal meiotic recombination+++GO:0016571///histone methylation+++GO:0016584///nucleosome positioning+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0043066///negative regulation of apoptotic process+++GO:0044648///histone H3-K4 dimethylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048232///male gamete generation+++GO:0051321///meiotic cell cycle+++GO:0051567///histone H3-K9 methylation+++GO:0051568///histone H3-K4 methylation+++GO:0060903///positive regulation of meiosis I+++GO:0080182///histone H3-K4 trimethylation+++GO:0097198///histone H3-K36 trimethylation+++GO:0097676///histone H3-K36 dimethylation+++GO:0097692///histone H3-K4 monomethylation+++GO:1905437///positive regulation of histone H3-K4 trimethylation+++GO:1905516///positive regulation of fertilization+++GO:1990918///double-strand break repair involved in meiotic recombination+++GO:2001255///positive regulation of histone H3-K36 trimethylation" 21339 21339 'Taf1a' mRNA 319 280 271 7.49 6.41 6.72 4.6 4.44 4.45 6.873333333 4.496666667 226 213 211 290 216.6666667 0.008921341 -0.431681035 GO:0000120///RNA polymerase I transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton GO:0003677///DNA binding+++GO:0005515///protein binding GO:0006360///transcription by RNA polymerase I 213391 213391 'Rassf4' mRNA 1613 1596 1478 13.45 13.09 13.08 21.16 21.77 20.2 13.20666667 21.04333333 2922 2937 2700 1562.333333 2853 9.01E-36 0.858109447 04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005575///cellular_component GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007165///signal transduction 213393 213393 'Depp1' mRNA 67 64 66 3.07 2.9 3.21 2.08 2.99 2.86 3.06 2.643333333 52 73 69 65.66666667 64.66666667 0.939806305 -0.03195137 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0010506///regulation of autophagy 21340 21340 'Taf1b' mRNA 505 526 455 14.24 14.63 13.61 9.86 11.94 9.83 14.16 10.54333333 402 473 387 495.3333333 420.6666667 0.086071797 -0.244100586 GO:0000120///RNA polymerase I transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005668///RNA polymerase transcription factor SL1 complex+++GO:0005730///nucleolus+++GO:0070860///RNA polymerase I core factor complex GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006360///transcription by RNA polymerase I+++GO:0042790///nucleolar large rRNA transcription by RNA polymerase I 213402 213402 'Armc2' mRNA 415 399 416 4.64 4.38 5.05 0.71 0.89 0.68 4.69 0.76 69 91 69 410 76.33333333 3.98E-41 -2.437056998 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0030154///cell differentiation+++GO:0044782///cilium organization 213409 213409 'Lemd1' mRNA 697 684 693 32.3 31.3 33.46 19.83 21.48 20.54 32.35333333 20.61666667 500 483 464 691.3333333 482.3333333 1.36E-06 -0.532220579 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21341 21341 'Taf1c' mRNA 253.17 276.77 229.17 4.21 4.55 4.04 4.85 4.65 4.92 4.266666667 4.806666667 335.78 312.74 330.68 253.0366667 326.4 0.021649008 0.356516107 GO:0000120///RNA polymerase I transcription factor complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006360///transcription by RNA polymerase I 213417 213417 'Klhdc8a' mRNA 291 267 106 7.65 6.8 2.84 1.27 1.78 1.99 5.763333333 1.68 58 76 85 221.3333333 73 2.35E-07 -1.590915249 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21343 21343 'Taf6' mRNA 1270.89 1223.79 1336.54 30.21 28.31 33.56 24.55 22.59 22.75 30.69333333 23.29666667 1189.63 1067.42 1071.79 1277.073333 1109.613333 0.028313058 -0.218006344 03022///Basal transcription factors GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0033276///transcription factor TFTC complex+++GO:0046695///SLIK (SAGA-like) complex+++GO:0071339///MLL1 complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046982///protein heterodimerization activity "GO:0006352///DNA-templated transcription, initiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0008285///negative regulation of cell proliferation+++GO:0016573///histone acetylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045786///negative regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 213435 213435 'Mylk3' mRNA 261 261 297 4.68 4.47 5.54 2.18 1.38 2.06 4.896666667 1.873333333 145 89 129 273 121 7.22E-09 -1.192740438 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0004687///myosin light chain kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0002528///regulation of vascular permeability involved in acute inflammatory response+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0045214///sarcomere organization+++GO:0048769///sarcomerogenesis+++GO:0055003///cardiac myofibril assembly+++GO:0060298///positive regulation of sarcomere organization+++GO:0071347///cellular response to interleukin-1 213438 213438 'P2ry10b' mRNA 7 1.97 2 0.13 0.04 0.04 1.43 2.33 1.84 0.07 1.866666667 91 145 112.87 3.656666667 116.29 2.62E-19 5.116034322 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 213439 213439 'Gpr174' mRNA 0 1 0 0 0.01 0 0.01 0.04 0.01 0.003333333 0.02 1 4 1 0.333333333 2 0.386106785 2.480518094 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045125///bioactive lipid receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0043029///T cell homeostasis+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 21345 21345 'Tagln' mRNA 158.18 130.42 184.73 5.85 4.75 7.24 8.33 7.72 7.29 5.946666667 7.78 258.98 234.21 219.24 157.7766667 237.4766667 0.005852731 0.571950157 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0030855///epithelial cell differentiation 213452 213452 'Dstyk' mRNA 1392 1575 1224 11.73 12.99 10.77 7.72 7.2 7.75 11.83 7.556666667 1056 966 1024 1397 1015.333333 2.00E-07 -0.468758543 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 213454 213454 'Gm378' mRNA 2 3 4 0.18 0.27 0.39 0 0.17 0.17 0.28 0.113333333 0 2 2 3 1.333333333 0.577538 -1.181213179 21346 21346 'Tagln2' mRNA 684 681 612 29.63 29.11 28.13 219.88 198.9 221.13 28.95666667 213.3033333 5829 5144 5670 659 5547.666667 0 3.062399508 GO:0005856///cytoskeleton GO:0030855///epithelial cell differentiation 213464 213464 'Rbbp5' mRNA 785.37 837.54 817.93 10.58 11.05 12.03 10.74 10.72 11.73 11.22 11.06333333 883.13 863.81 927.78 813.6133333 891.5733333 0.284744131 0.119826293 04934///Cushing syndrome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex+++GO:0071339///MLL1 complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific) GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043627///response to estrogen+++GO:0051568///histone H3-K4 methylation 213469 213469 'Lgi3' mRNA 6 7 9 0.1 0.12 0.16 0.61 0.54 0.48 0.126666667 0.543333333 41 35 31 7.333333333 35.66666667 9.63E-05 2.264306561 GO:0005576///extracellular region+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0003824///catalytic activity+++GO:0005515///protein binding GO:0006887///exocytosis+++GO:0017157///regulation of exocytosis 213484 213484 'Nudt18' mRNA 581 617 587 8.15 8.51 8.74 8.31 8.57 8.53 8.466666667 8.47 683 687 678 595 682.6666667 0.103210625 0.186670225 GO:0005575///cellular_component GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0044715///8-oxo-dGDP phosphatase activity+++GO:0044716///8-oxo-GDP phosphatase activity+++GO:0044717///8-hydroxy-dADP phosphatase activity+++GO:0046872///metal ion binding GO:0009117///nucleotide metabolic process+++GO:0046057///dADP catabolic process+++GO:0046067///dGDP catabolic process+++GO:0046712///GDP catabolic process 21349 21349 'Tal1' mRNA 17 8 3 0.23 0.1 0.04 0.1 0.13 0.2 0.123333333 0.143333333 9 11 17 9.333333333 12.33333333 0.705007912 0.410660969 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex+++GO:0033193///Lsd1/2 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0042826///histone deacetylase binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007275///multicellular organism development+++GO:0007626///locomotory behavior+++GO:0021527///spinal cord association neuron differentiation+++GO:0030097///hemopoiesis+++GO:0030099///myeloid cell differentiation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030220///platelet formation+++GO:0030221///basophil differentiation+++GO:0031334///positive regulation of protein complex assembly+++GO:0035162///embryonic hemopoiesis+++GO:0035855///megakaryocyte development+++GO:0042127///regulation of cell proliferation+++GO:0043249///erythrocyte maturation+++GO:0045165///cell fate commitment+++GO:0045637///regulation of myeloid cell differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045799///positive regulation of chromatin assembly or disassembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048699///generation of neurons+++GO:0051781///positive regulation of cell division+++GO:0060018///astrocyte fate commitment+++GO:0060216///definitive hemopoiesis+++GO:0060217///hemangioblast cell differentiation+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060375///regulation of mast cell differentiation+++GO:2000036///regulation of stem cell population maintenance" 213491 213491 'Szrd1' mRNA 836.51 758.01 746.38 13.22 11.88 12.58 19.87 17.37 17.72 12.56 18.32 1427.64 1193 1227 780.3 1282.546667 1.11E-13 0.704324689 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 213498 213498 'Arhgef11' mRNA 338.43 256.28 329.47 2.64 1.97 2.91 4.02 2.11 3.55 2.506666667 3.226666667 539.2 297.26 505.2 308.06 447.22 0.012921272 0.518529332 "04270///Vascular smooth muscle contraction+++04928///Parathyroid hormone synthesis, secretion and action+++05130///Pathogenic Escherichia coli infection+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer" GO:0005737///cytoplasm+++GO:0016020///membrane GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding "GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050790///regulation of catalytic activity" 213499 213499 'Fbxo42' mRNA 1148 1189 1142 10.37 10.59 10.87 9.56 9.67 8.96 10.61 9.396666667 1220 1199 1113 1159.666667 1177.333333 0.933133791 0.009763056 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21350 21350 'Tal2' mRNA 0 1 3 0 0.02 0.06 0.22 0.16 0.28 0.026666667 0.22 14 10 17 1.333333333 13.66666667 0.004487668 3.327034113 "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009791///post-embryonic development+++GO:0021794///thalamus development+++GO:0030901///midbrain development+++GO:0035264///multicellular organism growth 21351 21351 'Taldo1' mRNA 4721 4876 4695 224.6 229.01 236.98 244.64 257.44 252.11 230.1966667 251.3966667 5903 6059 5883 4764 5948.333333 1.71E-07 0.308658548 00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004801///sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity+++GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0048029///monosaccharide binding "GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0009052///pentose-phosphate shunt, non-oxidative branch+++GO:0019682///glyceraldehyde-3-phosphate metabolic process" 213522 213522 'Plekhg6' mRNA 174 212 188 3.14 3.78 3.61 3.86 3.41 3.3 3.51 3.523333333 244 211 203 191.3333333 219.3333333 0.385059695 0.184485681 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0030054///cell junction+++GO:0032154///cleavage furrow+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0008150///biological_process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 213527 213527 'Pth2r' mRNA 14.15 14 4 0.21 0.25 0.07 0.05 0 0.02 0.176666667 0.023333333 3 0 3 10.71666667 2 0.048131083 -2.412691213 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004991///parathyroid hormone receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis 21353 21353 'Tank' mRNA 705 688 684 19.57 18.88 20.16 27.9 26.71 28.69 19.53666667 27.76666667 1167 1086 1147 692.3333333 1133.333333 9.16E-15 0.698585975 04140///Autophagy - animal+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071479///cellular response to ionizing radiation+++GO:1903003///positive regulation of protein deubiquitination+++GO:2000158///positive regulation of ubiquitin-specific protease activity 213539 213539 'Bag2' mRNA 1114 1109 982 35.34 34.67 33.05 8.25 9.22 10.38 34.35333333 9.283333333 299 326 364 1068.333333 329.6666667 6.35E-55 -1.705103556 04141///Protein processing in endoplasmic reticulum GO:0005874///microtubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0101031///chaperone complex+++GO:1901588///dendritic microtubule GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0048156///tau protein binding+++GO:0051087///chaperone binding GO:0010954///positive regulation of protein processing+++GO:0019538///protein metabolic process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0050821///protein stabilization+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1904667///negative regulation of ubiquitin protein ligase activity 21354 21354 'Tap1' mRNA 832 856 858 15.54 15.7 16.97 31.08 33.81 30.72 16.07 31.87 1917 2038 1836 848.6666667 1930.333333 2.79E-43 1.173492276 02010///ABC transporters+++04145///Phagosome+++04612///Antigen processing and presentation+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05340///Primary immunodeficiency GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0034451///centriolar satellite+++GO:0042824///MHC class I peptide loading complex+++GO:0042825///TAP complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015433///peptide antigen-transporting ATPase activity+++GO:0015440///peptide-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0023029///MHC class Ib protein binding+++GO:0042287///MHC protein binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0046980///tapasin binding+++GO:1904680///peptide transmembrane transporter activity" "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0006952///defense response+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0046967///cytosol to ER transport+++GO:0055085///transmembrane transport" 213541 213541 'Ythdf2' mRNA 1532 1578 1651 20.26 20.52 23.16 23.49 22.47 23.07 21.31333333 23.01 2045 1911 1945 1587 1967 3.50E-04 0.295318676 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0034451///centriolar satellite+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:1990247///N6-methyladenosine-containing RNA binding GO:0001556///oocyte maturation+++GO:0002376///immune system process+++GO:0006402///mRNA catabolic process+++GO:0007049///cell cycle+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0007284///spermatogonial cell division+++GO:0030154///cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0034063///stress granule assembly+++GO:0043488///regulation of mRNA stability+++GO:0045087///innate immune response+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045948///positive regulation of translational initiation+++GO:0048477///oogenesis+++GO:0048598///embryonic morphogenesis+++GO:0050767///regulation of neurogenesis+++GO:0051301///cell division+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061157///mRNA destabilization+++GO:0070925///organelle assembly+++GO:0071425///hematopoietic stem cell proliferation+++GO:0098508///endothelial to hematopoietic transition+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:1903538///regulation of meiotic cell cycle process involved in oocyte maturation+++GO:1903679///positive regulation of cap-independent translational initiation+++GO:2000232///regulation of rRNA processing+++GO:2000737///negative regulation of stem cell differentiation 21355 21355 'Tap2' mRNA 1438 1513 1306 32.19 33.34 31.01 55.87 52.13 48.06 32.18 52.02 2871 2616 2391 1419 2626 6.68E-30 0.877327001 02010///ABC transporters+++04145///Phagosome+++04612///Antigen processing and presentation+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05340///Primary immunodeficiency GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0042824///MHC class I peptide loading complex+++GO:0042825///TAP complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015433///peptide antigen-transporting ATPase activity+++GO:0015440///peptide-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0023029///MHC class Ib protein binding+++GO:0042287///MHC protein binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0046980///tapasin binding+++GO:1904680///peptide transmembrane transporter activity" "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002237///response to molecule of bacterial origin+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002481///antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent+++GO:0002485///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent+++GO:0002489///antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent+++GO:0002591///positive regulation of antigen processing and presentation of peptide antigen via MHC class I+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0046967///cytosol to ER transport+++GO:0046968///peptide antigen transport+++GO:0055085///transmembrane transport+++GO:0065003///protein-containing complex assembly" 213550 213550 'Dis3l' mRNA 585 553 590 9.59 8.83 10.09 8.23 7.03 6.75 9.503333333 7.336666667 573 481 455 576 503 0.125490696 -0.21067488 03018///RNA degradation GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000175///3'-5'-exoribonuclease activity+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding "GO:0016075///rRNA catabolic process+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 213556 213556 'Plekhh2' mRNA 287 342 251 2.26 2.58 2.05 2.73 2.46 2.45 2.296666667 2.546666667 413 353 358 293.3333333 374.6666667 0.028399933 0.344431261 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030027///lamellipodium+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding GO:0030835///negative regulation of actin filament depolymerization 21356 21356 'Tapbp' mRNA 9039.05 9223.4 9112.3 181.8 182.6 194.42 222.44 227.91 226.37 186.2733333 225.5733333 12721.52 12729.51 12535.08 9124.916667 12662.03667 1.84E-17 0.460135818 04612///Antigen processing and presentation+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0042824///MHC class I peptide loading complex GO:0005515///protein binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0062061///TAP complex binding "GO:0002397///MHC class I protein complex assembly+++GO:0002398///MHC class Ib protein complex assembly+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0006952///defense response+++GO:0010468///regulation of gene expression+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0050823///peptide antigen stabilization+++GO:0061635///regulation of protein complex stability+++GO:0065003///protein-containing complex assembly" 21357 21357 'Tarbp2' mRNA 806 772 815 27.46 26.01 29.64 24.22 23.55 23.43 27.70333333 23.73333333 799 774 748 797.6666667 773.6666667 0.665196662 -0.05761858 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016442///RISC complex+++GO:0016604///nuclear body+++GO:0048471///perinuclear region of cytoplasm+++GO:0070578///RISC-loading complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0035197///siRNA binding+++GO:0035198///miRNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0070883///pre-miRNA binding GO:0006417///regulation of translation+++GO:0007286///spermatid development+++GO:0007338///single fertilization+++GO:0030422///production of siRNA involved in RNA interference+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035087///siRNA loading onto RISC involved in RNA interference+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035264///multicellular organism growth+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045070///positive regulation of viral genome replication+++GO:0045727///positive regulation of translation+++GO:0046782///regulation of viral transcription+++GO:0050689///negative regulation of defense response to virus by host+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0061351///neural precursor cell proliferation+++GO:0090065///regulation of production of siRNA involved in RNA interference+++GO:1903798///regulation of production of miRNAs involved in gene silencing by miRNA 213573 213573 'Cracr2b' mRNA 433.06 472.44 349.9 14.03 15.06 12.12 12.8 14.48 13.45 13.73666667 13.57666667 446.76 494.62 456.29 418.4666667 465.89 0.34149682 0.148915552 GO:0000139///Golgi membrane+++GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0033093///Weibel-Palade body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0002115///store-operated calcium entry+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0016197///endosomal transport+++GO:0032237///activation of store-operated calcium channel activity+++GO:0034613///cellular protein localization+++GO:0034776///response to histamine+++GO:0045063///T-helper 1 cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0051928///positive regulation of calcium ion transport+++GO:2001256///regulation of store-operated calcium entry 213575 213575 'Dync2li1' mRNA 1229 1278 1188 54.48 55.91 55.87 31.5 34.07 32.41 55.42 32.66 816 861 812 1231.666667 829.6666667 2.98E-11 -0.580712639 04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045177///apical part of cell GO:0045504///dynein heavy chain binding GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0030030///cell projection organization+++GO:0035721///intraciliary retrograde transport+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0060271///cilium assembly+++GO:1902017///regulation of cilium assembly 213582 213582 'Map9' mRNA 1161 1203 1174 9.9 10.08 10.62 2.16 1.92 2.1 10.2 2.06 292 253 275 1179.333333 273.3333333 2.91E-91 -2.122387978 GO:0000235///astral microtubule+++GO:0005737///cytoplasm+++GO:0005818///aster+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle+++GO:1990023///mitotic spindle midzone GO:0008017///microtubule binding GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0046602///regulation of mitotic centrosome separation+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0090307///mitotic spindle assembly+++GO:1902412///regulation of mitotic cytokinesis 213603 213603 'Slc44a3' mRNA 3711 3605 3594 80.6 77.08 82.81 31.4 31.42 32.77 80.16333333 31.86333333 1663 1625 1680 3636.666667 1656 7.09E-69 -1.147268066 05231///Choline metabolism in cancer GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 213649 213649 'Arhgef19' mRNA 409 417 304 6.1 6.29 4.86 4.38 3.88 4.24 5.75 4.166666667 342 289 319 376.6666667 316.6666667 0.11337732 -0.257512458 GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0032956///regulation of actin cytoskeleton organization+++GO:0042060///wound healing+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity 21366 21366 'Slc6a6' mRNA 3274 3361 2930 28.1 28.35 26.71 42.04 38.04 41.53 27.72 40.53666667 5640 4989 5400 3188.333333 5343 3.24E-35 0.73429622 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0031528///microvillus membrane+++GO:0043025///neuronal cell body+++GO:0098797///plasma membrane protein complex+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0001761///beta-alanine transmembrane transporter activity+++GO:0005368///taurine transmembrane transporter activity+++GO:0005369///taurine:sodium symporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015185///gamma-aminobutyric acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022858///alanine transmembrane transporter activity+++GO:0030977///taurine binding GO:0001762///beta-alanine transport+++GO:0006836///neurotransmitter transport+++GO:0010940///positive regulation of necrotic cell death+++GO:0015734///taurine transport+++GO:0032328///alanine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0045597///positive regulation of cell differentiation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051939///gamma-aminobutyric acid import+++GO:0055085///transmembrane transport+++GO:0071705///nitrogen compound transport+++GO:0089718///amino acid import across plasma membrane+++GO:0098739///import across plasma membrane 21367 21367 'Cntn2' mRNA 22.54 10.09 16.39 0.12 0.05 0.1 0.07 0.08 0.05 0.09 0.066666667 15.5 15.75 9.64 16.34 13.63 0.725758017 -0.314776197 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0033268///node of Ranvier+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043209///myelin sheath+++GO:0044224///juxtaparanode region of axon+++GO:0045202///synapse+++GO:0099025///anchored component of postsynaptic membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0043621///protein self-association+++GO:0098632///cell-cell adhesion mediator activity GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0002021///response to dietary excess+++GO:0002023///reduction of food intake in response to dietary excess+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0007420///brain development+++GO:0007612///learning+++GO:0007628///adult walking behavior+++GO:0010769///regulation of cell morphogenesis involved in differentiation+++GO:0010954///positive regulation of protein processing+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0022010///central nervous system myelination+++GO:0031133///regulation of axon diameter+++GO:0031175///neuron projection development+++GO:0031623///receptor internalization+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0045444///fat cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048710///regulation of astrocyte differentiation+++GO:0060168///positive regulation of adenosine receptor signaling pathway+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0071206///establishment of protein localization to juxtaparanode region of axon+++GO:0097090///presynaptic membrane organization+++GO:0098609///cell-cell adhesion 213673 213673 '9530068E07Rik' mRNA 5150 5477 5430 116.44 121.92 130.24 124.2 119.5 119.37 122.8666667 121.0233333 6318 5936 5879 5352.333333 6044.333333 0.014860443 0.161813226 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 213696 213696 'Duoxa1' mRNA 3 4 0 0.12 0.15 0 0 0.04 0.14 0.09 0.06 0 1 4 2.333333333 1.666666667 0.863090843 -0.454479545 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031252///cell leading edge GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0008104///protein localization+++GO:0010729///positive regulation of hydrogen peroxide biosynthetic process+++GO:0015031///protein transport+++GO:0034613///cellular protein localization+++GO:0042743///hydrogen peroxide metabolic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0050727///regulation of inflammatory response+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000609///regulation of thyroid hormone generation 21371 21371 'Tbca' mRNA 699 693 727 101.7 100.6 112.29 153.39 156.77 160.23 104.8633333 156.7966667 1201 1192 1208 706.3333333 1200.333333 4.90E-16 0.751811448 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0015631///tubulin binding+++GO:0048487///beta-tubulin binding GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007023///post-chaperonin tubulin folding pathway 21372 21372 'Tbl1x' mRNA 2045 2062 2029 30.29 30.58 32.81 25.69 27.44 26.2 31.22666667 26.44333333 2012 2080 1968 2045.333333 2020 0.765318131 -0.029885606 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:0072686///mitotic spindle GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0007605///sensory perception of sound+++GO:0016575///histone deacetylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043627///response to estrogen+++GO:0045444///fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048545///response to steroid hormone+++GO:0050821///protein stabilization+++GO:0090263///positive regulation of canonical Wnt signaling pathway" 21374 21374 'Tbp' mRNA 570 628.97 634 17.79 19.34 20.99 19.22 16.52 18.29 19.37333333 18.01 708 594 652 610.99 651.3333333 0.596918197 0.07821921 03022///Basal transcription factors+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000120///RNA polymerase I transcription factor complex+++GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005672///transcription factor TFIIA complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0045120///pronucleus+++GO:0097550///transcriptional preinitiation complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001091///RNA polymerase II basal transcription factor binding+++GO:0001093///TFIIB-class transcription factor binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0019899///enzyme binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:0140223///general transcription initiation factor activity "GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006383///transcription by RNA polymerase III+++GO:0007283///spermatogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051123///RNA polymerase II preinitiation complex assembly" 21375 21375 'Tbr1' mRNA 2 2 1 0.02 0.02 0.01 0 0 0 0.016666667 0 0 0 0 1.666666667 0 0.330935189 -3.178038812 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding" "GO:0001661///conditioned taste aversion+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010092///specification of animal organ identity+++GO:0010468///regulation of gene expression+++GO:0010975///regulation of neuron projection development+++GO:0021764///amygdala development+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0021987///cerebral cortex development+++GO:0030182///neuron differentiation+++GO:0030902///hindbrain development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902667///regulation of axon guidance" 213753 213753 'Zfp598' mRNA 363 318 251 6.52 5.71 4.88 6.23 5.61 5.35 5.703333333 5.73 392 345 326 310.6666667 354.3333333 0.313098276 0.181936968 GO:0005829///cytosol GO:0016740///transferase activity+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006417///regulation of translation+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0072344///rescue of stalled ribosome+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process 21376 21376 'Tbrg1' mRNA 1273 1399 1305 47.77 51.77 51.95 64.63 59.67 58.26 50.49666667 60.85333333 1979 1783 1726 1325.666667 1829.333333 2.55E-08 0.451923461 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:1990173///protein localization to nucleoplasm 213760 213760 'Prepl' mRNA 1435.28 1475.01 1550.26 21.21 21.25 24.03 10.8 11.06 10.7 22.16333333 10.85333333 853.73 857 827.78 1486.85 846.17 6.08E-20 -0.827874425 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0006508///proteolysis+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043001///Golgi to plasma membrane protein transport+++GO:2000300///regulation of synaptic vesicle exocytosis" 213773 213773 'Tbl3' mRNA 846 899 847 18.73 19.6 19.89 23.06 19.95 20.06 19.40666667 21.02333333 1198 1012 1009 864 1073 0.002590503 0.299373335 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030686///90S preribosome+++GO:0032040///small-subunit processome GO:0034511///U3 snoRNA binding "GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing" 213783 213783 'Plekhg1' mRNA 718 694 533 4.09 3.69 2.93 2.4 2.27 2.82 3.57 2.496666667 499 482 555 648.3333333 512 0.007336042 -0.346976185 GO:0005654///nucleoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 213788 213788 'Chrm5' mRNA 12 2 5 0.3 0.07 0.1 0.17 0.06 0.15 0.156666667 0.126666667 6 3 7 6.333333333 5.333333333 0.863090843 -0.261372259 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++04810///Regulation of actin cytoskeleton+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0030594///neurotransmitter receptor activity "GO:0001696///gastric acid secretion+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0015872///dopamine transport+++GO:0019226///transmission of nerve impulse+++GO:0060079///excitatory postsynaptic potential+++GO:0060304///regulation of phosphatidylinositol dephosphorylation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 21379 21379 'Tbrg4' mRNA 229.08 240.82 202.6 4.59 4.87 4.42 7.19 7.08 8.25 4.626666667 7.506666667 398.25 398.67 454.47 224.1666667 417.13 9.73E-10 0.888657462 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0003723///RNA binding GO:0000963///mitochondrial RNA processing+++GO:0016071///mRNA metabolic process+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0090615///mitochondrial mRNA processing 21380 21380 'Tbx1' mRNA 551 620 108 15.04 16.72 3.22 3.52 8.86 9.09 11.66 7.156666667 140 346 359 426.3333333 281.6666667 0.578110582 -0.570884449 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001708///cell fate specification+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001945///lymph vessel development+++GO:0001974///blood vessel remodeling+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007389///pattern specification process+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0007605///sensory perception of sound+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0021644///vagus nerve morphogenesis+++GO:0030855///epithelial cell differentiation+++GO:0030878///thyroid gland development+++GO:0035176///social behavior+++GO:0035909///aorta morphogenesis+++GO:0042471///ear morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0042473///outer ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042693///muscle cell fate commitment+++GO:0043410///positive regulation of MAPK cascade+++GO:0043587///tongue morphogenesis+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045596///negative regulation of cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0048538///thymus development+++GO:0048644///muscle organ morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048752///semicircular canal morphogenesis+++GO:0048844///artery morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060017///parathyroid gland development+++GO:0060022///hard palate development+++GO:0060023///soft palate development+++GO:0060037///pharyngeal system development+++GO:0060325///face morphogenesis+++GO:0060415///muscle tissue morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0070166///enamel mineralization+++GO:0071300///cellular response to retinoic acid+++GO:0071600///otic vesicle morphogenesis+++GO:0072513///positive regulation of secondary heart field cardioblast proliferation+++GO:0090103///cochlea morphogenesis+++GO:0097152///mesenchymal cell apoptotic process+++GO:2000027///regulation of animal organ morphogenesis+++GO:2001037///positive regulation of tongue muscle cell differentiation+++GO:2001054///negative regulation of mesenchymal cell apoptotic process" 213819 213819 'Casd1' mRNA 757 638 594 12.86 10.7 10.49 6.55 6.24 6.61 11.35 6.466666667 432 395 416 663 414.3333333 1.26E-08 -0.688291717 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047186///N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity" GO:0005975///carbohydrate metabolic process 213827 213827 'Arcn1' mRNA 3037 3460 3519 47.83 53.61 58.78 58.92 60.8 57.4 53.40666667 59.04 4306 4340 4062 3338.666667 4236 5.34E-05 0.329176216 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0008344///adult locomotory behavior+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0021691///cerebellar Purkinje cell layer maturation+++GO:0043473///pigmentation+++GO:0048193///Golgi vesicle transport+++GO:0051645///Golgi localization" 21384 21384 'Tbx15' mRNA 76 57 48 1.16 0.85 0.82 0.82 0.99 0.93 0.943333333 0.913333333 59 69 68 60.33333333 65.33333333 0.806988594 0.109384449 GO:0005634///nucleus+++GO:0090571///RNA polymerase II transcription repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis" 21385 21385 'Tbx2' mRNA 1911 1831 932 29.15 27.47 15.08 8.12 9.81 11.21 23.9 9.713333333 613 723 819 1558 718.3333333 8.98E-04 -1.111358055 04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003256///regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0003272///endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007521///muscle cell fate determination+++GO:0007569///cell aging+++GO:0008016///regulation of heart contraction+++GO:0008284///positive regulation of cell proliferation+++GO:0035050///embryonic heart tube development+++GO:0035909///aorta morphogenesis+++GO:0036302///atrioventricular canal development+++GO:0042733///embryonic digit morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048738///cardiac muscle tissue development+++GO:0051145///smooth muscle cell differentiation+++GO:0060021///roof of mouth development+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060465///pharynx development+++GO:0060560///developmental growth involved in morphogenesis+++GO:0060596///mammary placode formation+++GO:0072105///ureteric peristalsis+++GO:0090398///cellular senescence+++GO:1901208///negative regulation of heart looping+++GO:1901211///negative regulation of cardiac chamber formation+++GO:1905072///cardiac jelly development+++GO:1905222///atrioventricular canal morphogenesis" 21386 21386 'Tbx3' mRNA 1463 1321 1343 16.03 14.3 15.85 9.4 8.36 9.18 15.39333333 8.98 975 843 926 1375.666667 914.6666667 2.10E-11 -0.601899758 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0003007///heart morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003167///atrioventricular bundle cell differentiation+++GO:0003205///cardiac chamber development+++GO:0003272///endocardial cushion formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007569///cell aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0009887///animal organ morphogenesis+++GO:0010159///specification of animal organ position+++GO:0019827///stem cell population maintenance+++GO:0021761///limbic system development+++GO:0030539///male genitalia development+++GO:0030540///female genitalia development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030879///mammary gland development+++GO:0032275///luteinizing hormone secretion+++GO:0035050///embryonic heart tube development+++GO:0035108///limb morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035136///forelimb morphogenesis+++GO:0036302///atrioventricular canal development+++GO:0042127///regulation of cell proliferation+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046884///follicle-stimulating hormone secretion+++GO:0048332///mesoderm morphogenesis+++GO:0051145///smooth muscle cell differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:0060021///roof of mouth development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060412///ventricular septum morphogenesis+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060596///mammary placode formation+++GO:0060923///cardiac muscle cell fate commitment+++GO:0060931///sinoatrial node cell development+++GO:0072105///ureteric peristalsis+++GO:0090398///cellular senescence+++GO:1905072///cardiac jelly development+++GO:1905222///atrioventricular canal morphogenesis+++GO:2000137///negative regulation of cell proliferation involved in heart morphogenesis+++GO:2000648///positive regulation of stem cell proliferation" 21387 21387 'Tbx4' mRNA 1 1 5 0.02 0.02 0.1 0 0 0.03 0.046666667 0.01 0 0 2 2.333333333 0.666666667 0.488530428 -1.853934073 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0001525///angiogenesis+++GO:0001708///cell fate specification+++GO:0002009///morphogenesis of an epithelium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0035108///limb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:1990401///embryonic lung development" 21389 21389 'Tbx6' mRNA 38 30 19 1.28 1 0.68 0.35 0.39 0.46 0.986666667 0.4 12 13 15 29 13.33333333 0.055764785 -1.122042665 GO:0000785///chromatin+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001707///mesoderm formation+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0003205///cardiac chamber development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0014043///negative regulation of neuron maturation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0032525///somite rostral/caudal axis specification+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045944///positive regulation of transcription by RNA polymerase II" 213895 213895 'Bms1' mRNA 628 606 532 7.81 7.38 7.05 7.73 7.64 8.05 7.413333333 7.806666667 717 690 725 588.6666667 710.6666667 0.016726001 0.262153249 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030686///90S preribosome GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0034511///U3 snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0042254///ribosome biogenesis" 21390 21390 'Tbxa2r' mRNA 73 105 94 2.34 3.28 3.18 2.58 2.2 1.84 2.933333333 2.206666667 93 79 64 90.66666667 78.66666667 0.535803904 -0.219222034 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04611///Platelet activation GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0004930///G protein-coupled receptor activity+++GO:0004960///thromboxane receptor activity+++GO:0004961///thromboxane A2 receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007584///response to nutrient+++GO:0019229///regulation of vasoconstriction+++GO:0019932///second-messenger-mediated signaling+++GO:0030194///positive regulation of blood coagulation+++GO:0032496///response to lipopolysaccharide+++GO:0033574///response to testosterone+++GO:0038193///thromboxane A2 signaling pathway+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0045766///positive regulation of angiogenesis+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis 21391 21391 'Tbxas1' mRNA 944.4 992.77 878.03 3.11 4.28 3.17 32.08 34.8 32.72 3.52 33.2 2304.09 2229.03 2153.9 938.4 2229.006667 2.81E-64 1.238044061 00590///Arachidonic acid metabolism+++04611///Platelet activation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0004796///thromboxane-A synthase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0036134///12-hydroxyheptadecatrienoic acid synthase activity+++GO:0046872///metal ion binding" GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006690///icosanoid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0030644///cellular chloride ion homeostasis+++GO:0045471///response to ethanol+++GO:0045907///positive regulation of vasoconstriction+++GO:0070542///response to fatty acid 21393 21393 'Tcap' mRNA 41 67 48 2.8 4.53 3.48 0.12 0.43 0.49 3.603333333 0.346666667 2 7 8 52 5.666666667 2.54E-08 -3.201936098 GO:0005737///cytoplasm+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0031674///I band "GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0030674///protein binding, bridging+++GO:0031432///titin binding+++GO:0036122///BMP binding+++GO:0044325///ion channel binding+++GO:0051373///FATZ binding+++GO:0070080///titin Z domain binding" GO:0001756///somitogenesis+++GO:0003009///skeletal muscle contraction+++GO:0003300///cardiac muscle hypertrophy+++GO:0007512///adult heart development+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0030240///skeletal muscle thin filament assembly+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0030916///otic vesicle formation+++GO:0035995///detection of muscle stretch+++GO:0045214///sarcomere organization+++GO:0048739///cardiac muscle fiber development+++GO:0048769///sarcomerogenesis+++GO:0055003///cardiac myofibril assembly+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction 213945 213945 'Col28a1' mRNA 34 23 53 0.38 0.25 0.62 1.64 1.13 1.51 0.416666667 1.426666667 174 118 154 36.66666667 148.6666667 5.68E-10 1.991681698 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0030414///peptidase inhibitor activity GO:0007155///cell adhesion+++GO:0010466///negative regulation of peptidase activity+++GO:0030198///extracellular matrix organization 213948 213948 'Atg9b' mRNA 129.67 125.35 104.75 1.8 1.71 1.54 0.74 0.42 0.65 1.683333333 0.603333333 61.29 34.11 51.91 119.9233333 49.10333333 7.28E-06 -1.305825412 04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal GO:0000407///phagophore assembly site+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0044805///late nucleophagy 213956 213956 'Fam83f' mRNA 781 719 659 14.18 12.97 12.72 6.58 7.12 7.67 13.29 7.123333333 410 432 470 719.6666667 437.3333333 2.66E-10 -0.727780561 GO:0005575///cellular_component GO:0019901///protein kinase binding GO:0007165///signal transduction 213980 213980 'Fbxw10' mRNA 104 139 118 1.74 2.35 2.14 0.68 0.52 0.88 2.076666667 0.693333333 47 34 57 120.3333333 46 2.12E-06 -1.39955177 GO:0005575///cellular_component GO:0008150///biological_process 213988 213988 'Tnrc6b' mRNA 2814 2686 2542 8.43 7.91 8.08 5.73 4.53 5.22 8.14 5.16 2202 1702 1943 2680.666667 1949 1.29E-08 -0.472962272 GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0006417///regulation of translation+++GO:0031047///gene silencing by RNA+++GO:0035195///gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1905618///positive regulation of miRNA mediated inhibition of translation" 213989 213989 'Tmem82' mRNA 85.61 67.64 64.59 2.35 1.83 1.88 2.83 3.67 2.7 2.02 3.066666667 118.51 149.98 109.3 72.61333333 125.93 0.003675929 0.791845207 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 21399 21399 'Tcea1' mRNA 1948.34 2080.02 2008.94 40.45 42.5 44.23 40.29 39.9 41.39 42.39333333 40.52666667 2233.48 2159.91 2220.4 2012.433333 2204.596667 0.131840634 0.11908774 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003746///translation elongation factor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006414///translational elongation+++GO:0030218///erythrocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901919///positive regulation of exoribonuclease activity" 213990 213990 'Agap3' mRNA 463 446 350 9.73 9.19 7.92 9.11 9.17 9.46 8.946666667 9.246666667 488 476 493 419.6666667 485.6666667 0.151732911 0.203489516 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016605///PML body+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005525///GTP binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0030578///PML body organization+++GO:0034614///cellular response to reactive oxygen species+++GO:0034644///cellular response to UV+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 213993 213993 'Ccdc186' mRNA 1457 1611 1437 11.97 13.02 12.54 8.87 8.2 8.02 12.51 8.363333333 1242 1124 1086 1501.666667 1150.666667 2.63E-06 -0.395732792 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network GO:0031267///small GTPase binding GO:0009617///response to bacterium+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0042593///glucose homeostasis+++GO:0099518///vesicle cytoskeletal trafficking 21400 21400 'Tcea2' mRNA 330 311 309 14.69 13.97 14.92 8.38 8.18 7.49 14.52666667 8.016666667 216 219 185 316.6666667 206.6666667 9.68E-05 -0.627564197 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003746///translation elongation factor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006414///translational elongation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 21401 21401 'Tcea3' mRNA 467 396 412 22.35 18.81 21.1 16.15 14.77 14.28 20.75333333 15.06666667 387 345 331 425 354.3333333 0.06167678 -0.275299319 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated" 21402 21402 'Skp1' mRNA 48211.66 49518.7 43768.9 1967.32 1993.05 1895.13 1142.98 1073.06 1108.23 1951.833333 1108.09 32174.44 29474.59 30186.46 47166.42 30611.83 1.29E-45 -0.634257552 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway+++04710///Circadian rhythm+++05131///Shigellosis+++05132///Salmonella infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0031519///PcG protein complex "GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019904///protein domain specific binding+++GO:0097602///cullin family protein binding+++GO:1990444///F-box domain binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0035518///histone H2A monoubiquitination+++GO:0051457///maintenance of protein location in nucleus+++GO:0070936///protein K48-linked ubiquitination+++GO:1904668///positive regulation of ubiquitin protein ligase activity 214048 214048 'Larp1b' mRNA 266.27 268.48 278.18 3.43 3.56 3.82 3.26 3.22 3.12 3.603333333 3.2 279.72 268.1 265.25 270.9766667 271.0233333 0.949920065 -0.013423118 GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule GO:0003674///molecular_function+++GO:0003723///RNA binding GO:0008150///biological_process+++GO:0045727///positive regulation of translation 21405 21405 'Hnf1a' mRNA 19 15 10 0.39 0.28 0.2 0.18 0.16 0.13 0.29 0.156666667 10 9 7 14.66666667 8.666666667 0.361830858 -0.763245498 04950///Maturity onset diabetes of the young GO:0000785///chromatin+++GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0045120///pronucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001824///blastocyst development+++GO:0001889///liver development+++GO:0001890///placenta development+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006633///fatty acid biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0008104///protein localization+++GO:0008203///cholesterol metabolic process+++GO:0009749///response to glucose+++GO:0015721///bile acid and bile salt transport+++GO:0015908///fatty acid transport+++GO:0016573///histone acetylation+++GO:0030073///insulin secretion+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030326///embryonic limb morphogenesis+++GO:0031016///pancreas development+++GO:0031018///endocrine pancreas development+++GO:0035623///renal glucose absorption+++GO:0042593///glucose homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0045453///bone resorption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046323///glucose import+++GO:0046883///regulation of hormone secretion+++GO:0048341///paraxial mesoderm formation+++GO:0048608///reproductive structure development+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060395///SMAD protein signal transduction" 214058 214058 'Megf11' mRNA 485 442.26 430.4 4 3.72 3.67 1.79 2.22 1.85 3.796666667 1.953333333 305.03 350.7 285.71 452.5533333 313.8133333 1.52E-04 -0.539828613 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0003674///molecular_function GO:0010842///retina layer formation+++GO:0034109///homotypic cell-cell adhesion 21406 21406 'Tcf12' mRNA 911 966 704 10.55 10.94 9.15 13.13 13.76 13.57 10.21333333 13.48666667 1189 1235.01 1225 860.3333333 1216.336667 1.31E-06 0.493977981 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035497///cAMP response element binding+++GO:0043425///bHLH transcription factor binding+++GO:0046332///SMAD binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:0071837///HMG box domain binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 214063 214063 'Dnajc16' mRNA 627 629 572 7.32 6.98 7.2 5.93 5.63 6.1 7.166666667 5.886666667 579 528 585 609.3333333 564 0.332654079 -0.122452136 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008150///biological_process 21408 21408 'Zfp354a' mRNA 189.14 144.99 153.64 2.52 1.9 2.18 1.05 0.92 0.86 2.2 0.943333333 91.5 79.18 72.78 162.59 81.15333333 1.79E-05 -1.018638645 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007576///nucleolar fragmentation+++GO:0051593///response to folic acid" 214084 214084 'Slc18a2' mRNA 395 385 403 5.62 5.39 6.08 2.99 2.6 2.89 5.696666667 2.826666667 242 205 226 394.3333333 224.3333333 1.84E-08 -0.828129511 04721///Synaptic vesicle cycle+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0044297///cell body+++GO:0098691///dopaminergic synapse+++GO:0098794///postsynapse+++GO:0098992///neuronal dense core vesicle+++GO:0099066///integral component of neuronal dense core vesicle membrane GO:0005275///amine transmembrane transporter activity+++GO:0005335///serotonin:sodium symporter activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0022857///transmembrane transporter activity+++GO:0031072///heat shock protein binding+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:1901363///heterocyclic compound binding GO:0001975///response to amphetamine+++GO:0006836///neurotransmitter transport+++GO:0007568///aging+++GO:0007626///locomotory behavior+++GO:0009636///response to toxic substance+++GO:0009791///post-embryonic development+++GO:0015842///aminergic neurotransmitter loading into synaptic vesicle+++GO:0015844///monoamine transport+++GO:0030073///insulin secretion+++GO:0035690///cellular response to drug+++GO:0042593///glucose homeostasis+++GO:0042908///xenobiotic transport+++GO:0051589///negative regulation of neurotransmitter transport+++GO:0051610///serotonin uptake+++GO:0055085///transmembrane transport+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0098700///neurotransmitter loading into synaptic vesicle 21410 21410 'Hnf1b' mRNA 1 0 0 0.03 0 0 0.05 0 0.06 0.01 0.036666667 2 0 3 0.333333333 1.666666667 0.509095757 2.198366096 04950///Maturity onset diabetes of the young GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001706///endoderm formation+++GO:0001714///endodermal cell fate specification+++GO:0001822///kidney development+++GO:0001826///inner cell mass cell differentiation+++GO:0001889///liver development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007492///endoderm development+++GO:0009743///response to carbohydrate+++GO:0009749///response to glucose+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0030073///insulin secretion+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030902///hindbrain development+++GO:0031016///pancreas development+++GO:0031018///endocrine pancreas development+++GO:0032922///circadian regulation of gene expression+++GO:0035565///regulation of pronephros size+++GO:0039020///pronephric nephron tubule development+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048793///pronephros development+++GO:0048806///genitalia development+++GO:0050673///epithelial cell proliferation+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060429///epithelium development+++GO:0060677///ureteric bud elongation+++GO:0060993///kidney morphogenesis+++GO:0061017///hepatoblast differentiation+++GO:0061296///negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis+++GO:0065004///protein-DNA complex assembly+++GO:0070365///hepatocyte differentiation+++GO:0072095///regulation of branch elongation involved in ureteric bud branching+++GO:0072164///mesonephric tubule development+++GO:0072176///nephric duct development+++GO:0072177///mesonephric duct development+++GO:0072179///nephric duct formation+++GO:0072181///mesonephric duct formation+++GO:1900212///negative regulation of mesenchymal cell apoptotic process involved in metanephros development" 214105 214105 'Sox30' mRNA 4 8 4 0.08 0.15 0.08 0.05 0.08 0.05 0.103333333 0.06 3 5 3 5.333333333 3.666666667 0.725652483 -0.539661445 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010369///chromocenter "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008013///beta-catenin binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007286///spermatid development+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031960///response to corticosteroid+++GO:0045944///positive regulation of transcription by RNA polymerase II 214106 214106 '4933430I17Rik' mRNA 28 19 14 0.7 0.37 0.28 0.51 0.62 0.38 0.45 0.503333333 27 29 22 20.33333333 26 0.593899688 0.350721875 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21411 21411 'Tcf20' mRNA 975.95 885.2 867.76 6.59 5.86 6.22 4.48 3.81 4.53 6.223333333 4.273333333 763.08 634.95 754.51 909.6366667 717.5133333 9.25E-04 -0.354752368 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 214111 214111 'Slc24a1' mRNA 10 8 2 0.11 0.09 0.02 0.07 0.06 0 0.073333333 0.043333333 8 6 0 6.666666667 4.666666667 0.75009672 -0.510373768 04744///Phototransduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane "GO:0005262///calcium channel activity+++GO:0008273///calcium, potassium:sodium antiporter activity+++GO:0015297///antiporter activity" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007601///visual perception+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0070588///calcium ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport 214112 214112 'Nipal4' mRNA 198 179 208 3.28 2.92 3.66 2.38 2.46 2.04 3.286666667 2.293333333 165 167 137 195 156.3333333 0.12282169 -0.333852176 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0015095///magnesium ion transmembrane transporter activity GO:0006811///ion transport+++GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 21413 21413 'Tcf4' mRNA 8846.86 8938.94 8472 42.69 42.75 42.84 22.93 20.96 22.2 42.76 22.03 5454 4991 5182.21 8752.6 5209.07 1.95E-49 -0.760764137 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016021///integral component of membrane+++GO:0070369///beta-catenin-TCF7L2 complex+++GO:1990907///beta-catenin-TCF complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001093///TFIIB-class transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0043621///protein self-association+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010629///negative regulation of gene expression+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0042118///endothelial cell activation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0065004///protein-DNA complex assembly+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway" 214133 214133 'Tet2' mRNA 839 819 801 4.79 4.59 4.85 3.81 3.48 3.74 4.743333333 3.676666667 769 687 733 819.6666667 729.6666667 0.088905786 -0.180330347 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0070579///methylcytosine dioxygenase activity GO:0001822///kidney development+++GO:0002318///myeloid progenitor cell differentiation+++GO:0006211///5-methylcytosine catabolic process+++GO:0006325///chromatin organization+++GO:0006493///protein O-linked glycosylation+++GO:0007049///cell cycle+++GO:0009791///post-embryonic development+++GO:0019857///5-methylcytosine metabolic process+++GO:0019858///cytosine metabolic process+++GO:0020027///hemoglobin metabolic process+++GO:0030097///hemopoiesis+++GO:0030099///myeloid cell differentiation+++GO:0035511///oxidative DNA demethylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048536///spleen development+++GO:0048872///homeostasis of number of cells+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0070989///oxidative demethylation+++GO:0072576///liver morphogenesis+++GO:0080111///DNA demethylation+++GO:0080182///histone H3-K4 trimethylation 214137 214137 'Arhgap29' mRNA 2186 2351 2200 21.42 22.69 23.06 26.77 28.21 27.05 22.39 27.34333333 3148 3240 3064 2245.666667 3150.666667 1.60E-12 0.477226231 GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 21414 21414 'Tcf7' mRNA 621.53 590.3 506.1 3.63 3.38 3.17 3.51 2.91 3.85 3.393333333 3.423333333 406.56 330.42 408.54 572.6433333 381.84 4.01E-06 -0.595779569 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05132///Salmonella infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:1990907///beta-catenin-TCF complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016055///Wnt signaling pathway+++GO:0021915///neural tube development+++GO:0030538///embryonic genitalia morphogenesis+++GO:0033153///T cell receptor V(D)J recombination+++GO:0042127///regulation of cell proliferation+++GO:0042492///gamma-delta T cell differentiation+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0045586///regulation of gamma-delta T cell differentiation+++GO:0046632///alpha-beta T cell differentiation+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048619///embryonic hindgut morphogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0071353///cellular response to interleukin-4" 21415 21415 'Tcf7l1' mRNA 365.5 410.49 346.04 5.93 6.68 6.19 3.68 4.5 4.89 6.266666667 4.356666667 286.96 311.54 363 374.01 320.5 0.159677514 -0.232179914 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04916///Melanogenesis+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05132///Salmonella infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:1990907///beta-catenin-TCF complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0030165///PDZ domain binding+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070644///vitamin D response element binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001779///natural killer cell differentiation+++GO:0002326///B cell lineage commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007369///gastrulation+++GO:0007399///nervous system development+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030098///lymphocyte differentiation+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0032496///response to lipopolysaccharide+++GO:0033077///T cell differentiation in thymus+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0035019///somatic stem cell population maintenance+++GO:0042493///response to drug+++GO:0043588///skin development+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048319///axial mesoderm morphogenesis+++GO:0048468///cell development+++GO:0048541///Peyer's patch development+++GO:0048863///stem cell differentiation+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060070///canonical Wnt signaling pathway+++GO:2000036///regulation of stem cell population maintenance+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 214150 214150 'Ago3' mRNA 788.5 765.59 702.04 4.23 4.2 4.08 4.1 3.78 3.92 4.17 3.933333333 821.22 670.59 772.59 752.0433333 754.8 0.965174505 -0.006711136 04361///Axon regeneration GO:0000794///condensed nuclear chromosome+++GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016442///RISC complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070578///RISC-loading complex "GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0090624///endoribonuclease activity, cleaving miRNA-paired mRNA" "GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0010501///RNA secondary structure unwinding+++GO:0010628///positive regulation of gene expression+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035279///mRNA cleavage involved in gene silencing by miRNA+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0072091///regulation of stem cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0098586///cellular response to virus+++GO:1901224///positive regulation of NIK/NF-kappaB signaling" 214158 214158 'Trim38' mRNA 1 2 1 0.04 0.08 0.04 0.05 0 0 0.053333333 0.016666667 2 0 0 1.333333333 0.666666667 0.763915354 -1.02501986 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032648///regulation of interferon-beta production+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045070///positive regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:0050687///negative regulation of defense response to virus+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070936///protein K48-linked ubiquitination" 21416 21416 'Tcf7l2' mRNA 817 770 768 10.6 9.9 10.67 10.72 9.65 11.25 10.39 10.54 952 839 962 785 917.6666667 0.043081641 0.212622992 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04520///Adherens junction+++04916///Melanogenesis+++04934///Cushing syndrome+++04936///Alcoholic liver disease+++05132///Salmonella infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body+++GO:0032993///protein-DNA complex+++GO:0070369///beta-catenin-TCF7L2 complex+++GO:0071664///catenin-TCF7L2 complex+++GO:1990907///beta-catenin-TCF complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001093///TFIIB-class transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0045295///gamma-catenin binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070016///armadillo repeat domain binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001678///cellular glucose homeostasis+++GO:0001701///in utero embryonic development+++GO:0005977///glycogen metabolic process+++GO:0006006///glucose metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0009791///post-embryonic development+++GO:0010629///negative regulation of gene expression+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010909///positive regulation of heparan sulfate proteoglycan biosynthetic process+++GO:0014003///oligodendrocyte development+++GO:0016055///Wnt signaling pathway+++GO:0016525///negative regulation of angiogenesis+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030538///embryonic genitalia morphogenesis+++GO:0031641///regulation of myelination+++GO:0032024///positive regulation of insulin secretion+++GO:0032092///positive regulation of protein binding+++GO:0032252///secretory granule localization+++GO:0032350///regulation of hormone metabolic process+++GO:0035019///somatic stem cell population maintenance+++GO:0035264///multicellular organism growth+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042118///endothelial cell activation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043570///maintenance of DNA repeat elements+++GO:0043588///skin development+++GO:0044334///canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition+++GO:0045444///fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046621///negative regulation of organ growth+++GO:0046827///positive regulation of protein export from nucleus+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048619///embryonic hindgut morphogenesis+++GO:0048625///myoblast fate commitment+++GO:0048641///regulation of skeletal muscle tissue development+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060070///canonical Wnt signaling pathway+++GO:0060325///face morphogenesis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0065004///protein-DNA complex assembly+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway+++GO:1901142///insulin metabolic process" 214162 214162 'Kmt2a' mRNA 1882 1787 1630 5.94 5.53 5.53 5.05 4.35 5 5.666666667 4.8 1848 1560 1758 1766.333333 1722 0.64706288 -0.047946809 00310///Lysine degradation+++04934///Cushing syndrome+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0035097///histone methyltransferase complex+++GO:0071339///MLL1 complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding+++GO:0070577///lysine-acetylated histone binding "GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008285///negative regulation of cell proliferation+++GO:0008542///visual learning+++GO:0009416///response to light stimulus+++GO:0009791///post-embryonic development+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0016571///histone methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0032259///methylation+++GO:0032411///positive regulation of transporter activity+++GO:0032922///circadian regulation of gene expression+++GO:0034968///histone lysine methylation+++GO:0035162///embryonic hemopoiesis+++GO:0035640///exploration behavior+++GO:0035864///response to potassium ion+++GO:0043984///histone H4-K16 acetylation+++GO:0044648///histone H3-K4 dimethylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048511///rhythmic process+++GO:0048536///spleen development+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050890///cognition+++GO:0051568///histone H3-K4 methylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0051899///membrane depolarization+++GO:0060216///definitive hemopoiesis+++GO:0065003///protein-containing complex assembly+++GO:0071440///regulation of histone H3-K14 acetylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0097692///histone H3-K4 monomethylation+++GO:1901674///regulation of histone H3-K27 acetylation+++GO:1905642///negative regulation of DNA methylation+++GO:2000615///regulation of histone H3-K9 acetylation" 21417 21417 'Zeb1' mRNA 1276.42 1302.18 1143.68 4.76 4.63 4.18 3.79 3 3.1 4.523333333 3.296666667 1212.95 962.47 1046.01 1240.76 1073.81 0.025640801 -0.220317147 05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer+++05215///Prostate cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010464///regulation of mesenchymal cell proliferation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030154///cell differentiation+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048513///animal organ development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048598///embryonic morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048752///semicircular canal morphogenesis+++GO:0048856///anatomical structure development+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:0051216///cartilage development+++GO:0071230///cellular response to amino acid stimulus+++GO:0090103///cochlea morphogenesis" 21418 21418 'Tfap2a' mRNA 16 13 7 0.25 0.19 0.1 0.14 0.11 0.16 0.18 0.136666667 10 8 12 12 10 0.796795434 -0.26399656 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005905///clathrin-coated pit "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0003151///outflow tract morphogenesis+++GO:0003334///keratinocyte development+++GO:0003404///optic vesicle morphogenesis+++GO:0003409///optic cup structural organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007423///sensory organ development+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0010172///embryonic body morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0014032///neural crest cell development+++GO:0021506///anterior neuropore closure+++GO:0021559///trigeminal nerve development+++GO:0021623///oculomotor nerve formation+++GO:0021884///forebrain neuron development+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0032496///response to lipopolysaccharide+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035136///forelimb morphogenesis+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042472///inner ear morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0045595///regulation of cell differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048485///sympathetic nervous system development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048730///epidermis morphogenesis+++GO:0048856///anatomical structure development+++GO:0060021///roof of mouth development+++GO:0060235///lens induction in camera-type eye+++GO:0060325///face morphogenesis+++GO:0060349///bone morphogenesis+++GO:0061029///eyelid development in camera-type eye+++GO:0061303///cornea development in camera-type eye+++GO:0070172///positive regulation of tooth mineralization+++GO:0071281///cellular response to iron ion+++GO:0071711///basement membrane organization+++GO:0072210///metanephric nephron development+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 214189 214189 'Scgn' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0045202///synapse GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1900271///regulation of long-term synaptic potentiation 21419 21419 'Tfap2b' mRNA 3 1 0 0.03 0.02 0 0.1 0.02 0.13 0.016666667 0.083333333 9 2 9 1.333333333 6.666666667 0.136981427 2.320926991 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0003091///renal water homeostasis+++GO:0006006///glucose metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007423///sensory organ development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010467///gene expression+++GO:0010842///retina layer formation+++GO:0010960///magnesium ion homeostasis+++GO:0030510///regulation of BMP signaling pathway+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0035810///positive regulation of urine volume+++GO:0035909///aorta morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043588///skin development+++GO:0045444///fat cell differentiation+++GO:0045595///regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048485///sympathetic nervous system development+++GO:0048745///smooth muscle tissue development+++GO:0048856///anatomical structure development+++GO:0050796///regulation of insulin secretion+++GO:0055062///phosphate ion homeostasis+++GO:0055074///calcium ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0072017///distal tubule development+++GO:0072044///collecting duct development+++GO:0072210///metanephric nephron development+++GO:0097070///ductus arteriosus closure+++GO:0097275///cellular ammonia homeostasis+++GO:0097276///cellular creatinine homeostasis+++GO:0097277///cellular urea homeostasis" 214191 214191 'Ttc24' mRNA 1192 1144 1170 29.79 28.15 31.01 2.59 2.85 2.51 29.65 2.65 119 128 112 1168.666667 119.6666667 2.26E-154 -3.300383119 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21420 21420 'Tfap2c' mRNA 0 2 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001829///trophectodermal cell differentiation+++GO:0001942///hair follicle development+++GO:0003334///keratinocyte development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008584///male gonad development+++GO:0019827///stem cell population maintenance+++GO:0021877///forebrain neuron fate commitment+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030718///germ-line stem cell population maintenance+++GO:0035019///somatic stem cell population maintenance+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042127///regulation of cell proliferation+++GO:0043588///skin development+++GO:0045682///regulation of epidermis development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048733///sebaceous gland development+++GO:0048856///anatomical structure development+++GO:0060598///dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation" 21422 21422 'Tfcp2' mRNA 756.12 818.03 812.01 12.65 13.19 14.09 7.88 7.75 8.32 13.31 7.983333333 558.01 521.33 558.15 795.3866667 545.83 2.04E-07 -0.556870314 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 21423 21423 'Tcf3' mRNA 1059 1011 320 19.96 18.76 6.61 7.05 10.05 10.6 15.11 9.233333333 418 587 619 796.6666667 541.3333333 0.393909688 -0.542077292 04550///Signaling pathways regulating pluripotency of stem cells+++05166///Human T-cell leukemia virus 1 infection+++05202///Transcriptional misregulation in cancer GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030165///PDZ domain binding+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:0070644///vitamin D response element binding+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001779///natural killer cell differentiation+++GO:0002326///B cell lineage commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007369///gastrulation+++GO:0007399///nervous system development+++GO:0009410///response to xenobiotic stimulus+++GO:0010628///positive regulation of gene expression+++GO:0030098///lymphocyte differentiation+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0032496///response to lipopolysaccharide+++GO:0033077///T cell differentiation in thymus+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0042493///response to drug+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0048541///Peyer's patch development+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 214230 214230 'Pak6' mRNA 28 34 39 0.35 0.41 0.53 0.47 0.64 0.57 0.43 0.56 42 55 50 33.66666667 49 0.229333802 0.52741422 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05170///Human immunodeficiency virus 1 infection+++05211///Renal cell carcinoma GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007612///learning+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0140058///neuron projection arborization+++GO:1990138///neuron projection extension 214239 214239 'Ccdc9b' mRNA 358 362 274 4.07 4.03 3.37 3.45 3.39 3.59 3.823333333 3.476666667 343 331 347 331.3333333 340.3333333 0.86431988 0.031718191 GO:0005575///cellular_component GO:0008150///biological_process 214240 214240 'Disp2' mRNA 353 425 404 2.83 3.36 3.43 0.63 0.68 0.57 3.206666667 0.626666667 91 94 79 394 88 1.80E-34 -2.175514796 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 21425 21425 'Tfeb' mRNA 479.36 540.94 468.61 11.03 12.41 11.55 12.4 13.22 12.88 11.66333333 12.83333333 645.89 673.06 635.82 496.3033333 651.59 8.19E-04 0.383429489 04137///Mitophagy - animal GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001892///embryonic placenta development+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006914///autophagy+++GO:0006959///humoral immune response+++GO:0007040///lysosome organization+++GO:0009267///cellular response to starvation+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0032418///lysosome localization+++GO:0034198///cellular response to amino acid starvation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050829///defense response to Gram-negative bacterium" 214253 214253 'Etnk2' mRNA 225 191 178 5.54 4.63 4.65 2.94 2.96 3.14 4.94 3.013333333 137 135 142 198 138 0.008533972 -0.530417024 00564///Glycerophospholipid metabolism GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004103///choline kinase activity+++GO:0004305///ethanolamine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0009791///post-embryonic development+++GO:0016310///phosphorylation+++GO:0035264///multicellular organism growth 214254 214254 'Nudt15' mRNA 152 171 139 2.61 2.89 2.54 2.66 2.85 3.67 2.68 3.06 178 186 238 154 200.6666667 0.084985192 0.373916212 GO:0005829///cytosol "GO:0004551///nucleotide diphosphatase activity+++GO:0008413///8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0035539///8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity+++GO:0036218///dTTP diphosphatase activity+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity" GO:0000278///mitotic cell cycle+++GO:0000302///response to reactive oxygen species+++GO:0006195///purine nucleotide catabolic process+++GO:0006203///dGTP catabolic process+++GO:0009217///purine deoxyribonucleoside triphosphate catabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0042262///DNA protection+++GO:0042738///exogenous drug catabolic process+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:1901292///nucleoside phosphate catabolic process 21426 21426 'Tfec' mRNA 35 37 41 0.49 0.5 0.83 5.8 5.34 6.21 0.606666667 5.783333333 211 198 228 37.66666667 212.3333333 1.13E-24 2.481485639 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034605///cellular response to heat+++GO:0045944///positive regulation of transcription by RNA polymerase II" 21427 21427 'Vps72' mRNA 1610.68 1591.7 1501.71 66.73 65.06 66.01 53.75 54.71 52.24 65.93333333 53.56666667 1489.94 1479.85 1400.95 1568.03 1456.913333 0.166110597 -0.117448242 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0042393///histone binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035019///somatic stem cell population maintenance+++GO:0043486///histone exchange" 21428 21428 'Mlx' mRNA 963.18 993.32 870.7 29.34 29.94 28.07 35.55 35.41 36.19 29.11666667 35.71666667 1328.77 1285.72 1298.28 942.4 1304.256667 2.36E-08 0.458751975 04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006913///nucleocytoplasmic transport+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 21429 21429 'Ubtf' mRNA 1934.97 1958.05 1861.17 28.52 28.44 28.16 23.21 21.59 25.19 28.37333333 23.33 1792.01 1662.95 1881.43 1918.063333 1778.796667 0.149045112 -0.120623272 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0001165///RNA polymerase I upstream control element sequence-specific DNA binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0097110///scaffold protein binding GO:0000183///chromatin silencing at rDNA+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006360///transcription by RNA polymerase I+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:1990830///cellular response to leukemia inhibitory factor 214290 214290 'Tut7' mRNA 1329 1346 1199 12.19 12.09 11.71 14.54 13.3 12.79 11.99666667 13.54333333 1848 1651 1571 1291.333333 1690 4.08E-06 0.377018593 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0050265///RNA uridylyltransferase activity+++GO:0070569///uridylyltransferase activity "GO:0001556///oocyte maturation+++GO:0010526///negative regulation of transposition, RNA-mediated+++GO:0010586///miRNA metabolic process+++GO:0031054///pre-miRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0071044///histone mRNA catabolic process+++GO:0071076///RNA 3' uridylation+++GO:1990074///polyuridylation-dependent mRNA catabolic process" 214292 214292 'Syna' mRNA 35 47 42 0.54 0.67 0.68 0.38 0.37 0.42 0.63 0.39 30 28 31 41.33333333 29.66666667 0.294938631 -0.490793818 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000768///syncytium formation by plasma membrane fusion+++GO:0007275///multicellular organism development+++GO:0007520///myoblast fusion+++GO:0060711///labyrinthine layer development 214301 214301 'Crygn' mRNA 7 16 20 0.87 1.99 2.65 3.06 2.25 1.81 1.836666667 2.373333333 28 20 16 14.33333333 21.33333333 0.464679244 0.547644078 GO:0005575///cellular_component GO:0005212///structural constituent of eye lens GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 214305 214305 'Hhipl1' mRNA 6 6 1 0.13 0.13 0.02 0.19 0.32 0.4 0.093333333 0.303333333 10 17 21 4.333333333 16 0.036198589 1.895820226 GO:0005576///extracellular region+++GO:0016020///membrane GO:0003824///catalytic activity+++GO:0005044///scavenger receptor activity GO:0006897///endocytosis+++GO:0008150///biological_process 214321 214321 'Gm4787' mRNA 10.72 13 16.27 0.24 0.29 0.39 0.33 0.22 0.3 0.306666667 0.283333333 17 11 15 13.33 14.33333333 0.887535875 0.119414617 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990913///sperm head plasma membrane GO:0003674///molecular_function+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0008584///male gonad development 214345 214345 'Lrrc1' mRNA 264 266 284 4.68 4.41 5.51 2.62 2.2 2.75 4.866666667 2.523333333 173 145 176 271.3333333 164.6666667 3.44E-05 -0.735458598 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane 214359 214359 'Tmem51' mRNA 1227 1283 1255 36.99 38.08 40.25 42.2 43.78 45.42 38.44 43.8 1601 1620 1666 1255 1629 7.37E-06 0.364280278 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 214384 214384 'Myocd' mRNA 5 3 1 0.05 0.03 0.01 0.01 0.02 0 0.03 0.01 2 3 0 3 1.666666667 0.707735688 -0.838850996 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0070514///SRF-myogenin-E12 complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0035035///histone acetyltransferase binding+++GO:0042826///histone deacetylase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070412///R-SMAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001560///regulation of cell growth by extracellular stimulus+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0003231///cardiac ventricle development+++GO:0003257///positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010832///negative regulation of myotube differentiation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0035065///regulation of histone acetylation+++GO:0035733///hepatic stellate cell activation+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0042692///muscle cell differentiation+++GO:0043388///positive regulation of DNA binding+++GO:0043954///cellular component maintenance+++GO:0045661///regulation of myoblast differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0048286///lung alveolus development+++GO:0048565///digestive tract development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051145///smooth muscle cell differentiation+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060065///uterus development+++GO:0060157///urinary bladder development+++GO:0060354///negative regulation of cell adhesion molecule production+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0097070///ductus arteriosus closure+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1900239///regulation of phenotypic switching+++GO:1901228///positive regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:2000721///positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation+++GO:2000724///positive regulation of cardiac vascular smooth muscle cell differentiation+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2001015///negative regulation of skeletal muscle cell differentiation" 214403 214403 'Gm4788' mRNA 6.02 9.04 5.06 0.12 0.18 0.11 0.78 0.55 0.39 0.136666667 0.573333333 43.73 31.15 22.15 6.706666667 32.34333333 3.72E-04 2.25332115 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0001851///complement component C3b binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0006956///complement activation+++GO:0008150///biological_process+++GO:0030449///regulation of complement activation 214424 214424 'Parp16' mRNA 423 386 428 9.66 8.68 10.35 6.03 6.04 7.23 9.563333333 6.433333333 304 296 351 412.3333333 317 0.009215028 -0.393109954 GO:0005622///intracellular+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019900///kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:1990404///protein ADP-ribosylase activity" GO:0006471///protein ADP-ribosylation+++GO:0006986///response to unfolded protein+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0060548///negative regulation of cell death+++GO:0070213///protein auto-ADP-ribosylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1990830///cellular response to leukemia inhibitory factor 214425 214425 'Cilp' mRNA 1 1 1 0.01 0.01 0.01 0 0.05 0.01 0.01 0.02 0 4 1 1 1.666666667 0.802477147 0.742835059 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0003674///molecular_function GO:0010629///negative regulation of gene expression+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0071560///cellular response to transforming growth factor beta stimulus 214444 214444 'Cdk5rap2' mRNA 2777 2919 2780 12.26 12.66 13.01 4.48 4.32 4.2 12.64333333 4.333333333 1171 1102 1061 2825.333333 1111.333333 4.45E-81 -1.35854393 GO:0000242///pericentriolar material+++GO:0000922///spindle pole+++GO:0000931///gamma-tubulin large complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0008274///gamma-tubulin ring complex+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0035371///microtubule plus-end+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097431///mitotic spindle pole GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0015631///tubulin binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0071889///14-3-3 protein binding "GO:0000132///establishment of mitotic spindle orientation+++GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007059///chromosome segregation+++GO:0007098///centrosome cycle+++GO:0007099///centriole replication+++GO:0007420///brain development+++GO:0022008///neurogenesis+++GO:0031023///microtubule organizing center organization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0045665///negative regulation of neuron differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046600///negative regulation of centriole replication+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint" 214459 214459 'Fnbp1l' mRNA 679 673 630 6.91 6.73 6.79 5.49 5.01 5.78 6.81 5.426666667 616 550 629 660.6666667 598.3333333 0.19868573 -0.154524783 05131///Shigellosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0008289///lipid binding+++GO:0051020///GTPase binding GO:0006897///endocytosis+++GO:0006900///vesicle budding from membrane+++GO:0006914///autophagy+++GO:0007165///signal transduction+++GO:0010324///membrane invagination+++GO:0016050///vesicle organization+++GO:0030050///vesicle transport along actin filament+++GO:0051491///positive regulation of filopodium assembly+++GO:0060271///cilium assembly+++GO:0072583///clathrin-dependent endocytosis+++GO:0097320///plasma membrane tubulation 214469 214469 'Fam168b' mRNA 1092 1154 1037 11.6 12.04 11.69 11.72 11.03 11.11 11.77666667 11.28666667 1274 1167 1167 1094.333333 1202.666667 0.179710737 0.124926852 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 214489 214489 'BC003965' mRNA 561 619 670 10.19 11.06 12.91 9.71 11.52 9.67 11.38666667 10.3 615 713 593 616.6666667 640.3333333 0.829720997 0.040301074 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 214498 214498 'Cdc73' mRNA 532.2 549.36 514.46 4.34 4.33 4.47 3.56 2.66 3.61 4.38 3.276666667 504.38 363.56 490.03 532.0066667 452.6566667 0.095617931 -0.246648959 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016593///Cdc73/Paf1 complex GO:0000993///RNA polymerase II complex binding+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0001711///endodermal cell fate commitment+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006378///mRNA polyadenylation+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010390///histone monoubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0016570///histone modification+++GO:0019827///stem cell population maintenance+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0031648///protein destabilization+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033523///histone H2B ubiquitination+++GO:0034402///recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex+++GO:0043066///negative regulation of apoptotic process+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0071222///cellular response to lipopolysaccharide+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 214505 214505 'Gnptg' mRNA 2596.45 2705.76 2326.87 109.55 111.62 104.87 100.68 97.2 95.39 108.68 97.75666667 2696.78 2505.2 2397.45 2543.026667 2533.143333 0.863090843 -0.015617069 04142///Lysosome GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003976///UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity+++GO:0042803///protein homodimerization activity GO:0046835///carbohydrate phosphorylation 21452 21452 'Tcn2' mRNA 5863 6021 5846 167.24 168.98 176.45 176.7 178 169.56 170.89 174.7533333 7120 6990 6605 5910 6905 3.68E-04 0.212107631 04977///Vitamin digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0031419///cobalamin binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006824///cobalt ion transport+++GO:0015889///cobalamin transport 214523 214523 'Tmprss4' mRNA 2 1 1 0.05 0.03 0.03 0.51 0.1 0.39 0.036666667 0.333333333 23 4 17 1.333333333 14.66666667 0.003788498 3.439873271 05164///Influenza A GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0016485///protein processing+++GO:0045967///negative regulation of growth rate+++GO:0046598///positive regulation of viral entry into host cell 21453 21453 'Tcof1' mRNA 592 529 580 7 6.14 7.28 7.5 7.98 7.77 6.806666667 7.75 731 762 735 567 742.6666667 0.001008769 0.376362341 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0030674///protein binding, bridging+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding" GO:0006417///regulation of translation+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development+++GO:0042790///nucleolar large rRNA transcription by RNA polymerase I 214531 214531 'Tmprss13' mRNA 37 19 33 0.62 0.31 0.59 0.13 0.21 0.08 0.506666667 0.14 9 14 5 29.66666667 9.333333333 0.008595429 -1.684237479 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0061436///establishment of skin barrier 21454 21454 'Tcp1' mRNA 2636.93 2763.46 2783.82 58.88 60.73 65.93 68.51 66.94 66.1 61.84666667 67.18333333 3524.93 3364.28 3293.58 2728.07 3394.263333 1.73E-05 0.301760042 GO:0000242///pericentriolar material+++GO:0000792///heterochromatin+++GO:0001669///acrosomal vesicle+++GO:0002199///zona pellucida receptor complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0044053///translocation of peptides or proteins into host cell cytoplasm+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:0090666///scaRNA localization to Cajal body+++GO:1901998///toxin transport+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:2000109///regulation of macrophage apoptotic process 214547 214547 'She' mRNA 80 84 37 0.74 0.76 0.36 0.38 0.57 0.27 0.62 0.406666667 47 69 33 67 49.66666667 0.355218327 -0.425923016 GO:0005575///cellular_component GO:0001784///phosphotyrosine residue binding 214552 214552 'Cep164' mRNA 546 556 605 5.23 5.19 6.08 4.7 5.12 5.25 5.5 5.023333333 595 614 636 569 615 0.499879975 0.098164442 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0045177///apical part of cell+++GO:0097539///ciliary transition fiber+++GO:0097729///9+2 motile cilium GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0030030///cell projection organization+++GO:0051301///cell division+++GO:0060271///cilium assembly 214572 214572 'Prmt7' mRNA 637 674 693 16.31 16.78 18.66 17.32 18.82 17.9 17.25 18.01333333 792 834 786 668 804 0.023923416 0.254355188 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016277///[myelin basic protein]-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0035241///protein-arginine omega-N monomethyltransferase activity+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0044020///histone methyltransferase activity (H4-R3 specific) "GO:0000387///spliceosomal snRNP assembly+++GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006479///protein methylation+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0030154///cell differentiation+++GO:0032259///methylation+++GO:0034969///histone arginine methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0035247///peptidyl-arginine omega-N-methylation+++GO:0043046///DNA methylation involved in gamete generation+++GO:0043985///histone H4-R3 methylation" 214575 214575 'Tdrd5' mRNA 14 12 6 0.24 0.14 0.1 0.25 0.33 0.44 0.16 0.34 19 25 33 10.66666667 25.66666667 0.049488016 1.268776806 GO:0005737///cytoplasm+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0071546///pi-body GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation 214579 214579 'Aldh5a1' mRNA 463 424 307 4.65 4.2 3.12 2.17 2.39 3.2 3.99 2.586666667 265 278 380 398 307.6666667 0.048712829 -0.374841719 "00250///Alanine, aspartate and glutamate metabolism+++00650///Butanoate metabolism" GO:0005739///mitochondrion "GO:0004777///succinate-semialdehyde dehydrogenase (NAD+) activity+++GO:0009013///succinate-semialdehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0031406///carboxylic acid binding+++GO:0042802///identical protein binding+++GO:0051287///NAD binding" GO:0006105///succinate metabolic process+++GO:0006536///glutamate metabolic process+++GO:0007417///central nervous system development+++GO:0009448///gamma-aminobutyric acid metabolic process+++GO:0009450///gamma-aminobutyric acid catabolic process+++GO:0009791///post-embryonic development+++GO:0042135///neurotransmitter catabolic process 214580 214580 'Pstk' mRNA 189.73 180.62 171.33 10.3 9.7 9.84 9.41 8.81 9.38 9.946666667 9.2 197.52 183.07 190.73 180.56 190.44 0.789023606 0.066625628 00450///Selenocompound metabolism+++00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043915///L-seryl-tRNA(Sec) kinase activity GO:0001514///selenocysteine incorporation+++GO:0006412///translation+++GO:0016310///phosphorylation+++GO:0097056///selenocysteinyl-tRNA(Sec) biosynthetic process 214585 214585 'Spg11' mRNA 619.47 632.78 579.44 4.19 4.2 4.15 3.17 2.83 3 4.18 3 537.83 467.65 493.15 610.5633333 499.5433333 0.009163578 -0.301494116 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse GO:0003674///molecular_function GO:0006606///protein import into nucleus+++GO:0007040///lysosome organization+++GO:0007268///chemical synaptic transmission+++GO:0007409///axonogenesis+++GO:0007528///neuromuscular junction development+++GO:0007613///memory+++GO:0008088///axo-dendritic transport+++GO:0021957///corticospinal tract morphogenesis+++GO:0033344///cholesterol efflux+++GO:0048167///regulation of synaptic plasticity+++GO:0048489///synaptic vesicle transport+++GO:0048675///axon extension+++GO:0048741///skeletal muscle fiber development+++GO:0051402///neuron apoptotic process+++GO:0061744///motor behavior+++GO:0090389///phagosome-lysosome fusion involved in apoptotic cell clearance+++GO:0090659///walking behavior+++GO:0097049///motor neuron apoptotic process+++GO:2001256///regulation of store-operated calcium entry 214593 214593 'Duox2' mRNA 0 1 1 0 0.01 0.01 0.02 0 0.02 0.006666667 0.013333333 2 0 3 0.666666667 1.666666667 0.681808723 1.293013728 04013///MAPK signaling pathway - fly+++04624///Toll and Imd signaling pathway+++04918///Thyroid hormone synthesis GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0031252///cell leading edge+++GO:0043020///NADPH oxidase complex+++GO:0045177///apical part of cell GO:0004601///peroxidase activity+++GO:0005509///calcium ion binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0020037///heme binding GO:0006590///thyroid hormone generation+++GO:0006952///defense response+++GO:0006979///response to oxidative stress+++GO:0009566///fertilization+++GO:0009615///response to virus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030282///bone mineralization+++GO:0030878///thyroid gland development+++GO:0035264///multicellular organism growth+++GO:0042403///thyroid hormone metabolic process+++GO:0042445///hormone metabolic process+++GO:0042446///hormone biosynthetic process+++GO:0042554///superoxide anion generation+++GO:0048839///inner ear development+++GO:0048855///adenohypophysis morphogenesis+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0051591///response to cAMP+++GO:0090303///positive regulation of wound healing+++GO:2000147///positive regulation of cell motility 214597 214597 'Sidt2' mRNA 1150 1401 1059 14.09 16.91 13.73 21.37 18.26 20.33 14.91 19.98666667 1970 1658 1824 1203.333333 1817.333333 4.19E-10 0.58568812 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035650///AP-1 adaptor complex binding+++GO:0051032///nucleic acid transmembrane transporter activity+++GO:0051033///RNA transmembrane transporter activity GO:0000902///cell morphogenesis+++GO:0003323///type B pancreatic cell development+++GO:0006401///RNA catabolic process+++GO:0009749///response to glucose+++GO:0042593///glucose homeostasis+++GO:0044342///type B pancreatic cell proliferation+++GO:0050658///RNA transport+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus 214601 214601 'Slc10a3' mRNA 368.28 405.98 344.97 10.59 11.3 10.42 15.08 15.02 15.19 10.77 15.09666667 608 590.65 593.82 373.0766667 597.49 8.57E-09 0.671244599 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008508///bile acid:sodium symporter activity+++GO:0015293///symporter activity GO:0010033///response to organic substance+++GO:0015721///bile acid and bile salt transport+++GO:0032526///response to retinoic acid+++GO:0055085///transmembrane transport 21461 21461 'Tcp10a' mRNA 0 2.73 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.91 0 0.750387006 -1.824848553 GO:0005634///nucleus+++GO:0005814///centriole GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association "GO:0045892///negative regulation of transcription, DNA-templated" 214616 214616 'Spata5l1' mRNA 48 54 6 1.16 1.28 0.15 0.42 0.97 0.71 0.863333333 0.7 20 45 33 36 32.66666667 0.881666752 -0.115037822 GO:0005737///cytoplasm+++GO:0005819///spindle GO:0003674///molecular_function+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0008150///biological_process 21462 21462 'Tcp10b' mRNA 5.3 8.92 12.9 0.15 0.24 0.39 0.24 0.1 0.25 0.26 0.196666667 10 3.77 9.91 9.04 7.893333333 0.863090843 -0.216060038 GO:0005634///nucleus+++GO:0005814///centriole GO:0003714///transcription corepressor activity "GO:0045892///negative regulation of transcription, DNA-templated" 214627 214627 'Tent4b' mRNA 378 351 326 4.41 4.05 4.12 3.53 3.38 2.96 4.193333333 3.29 343 325 282 351.6666667 316.6666667 0.334125461 -0.162173682 03018///RNA degradation GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031499///TRAMP complex GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0070568///guanylyltransferase activity GO:0006364///rRNA processing+++GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0010587///miRNA catabolic process+++GO:0031123///RNA 3'-end processing+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0033500///carbohydrate homeostasis+++GO:0043629///ncRNA polyadenylation+++GO:0043630///ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process+++GO:0043631///RNA polyadenylation+++GO:0051301///cell division+++GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0071044///histone mRNA catabolic process+++GO:0071050///snoRNA polyadenylation+++GO:0071076///RNA 3' uridylation+++GO:0071897///DNA biosynthetic process+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization 21463 21463 'Tcp11' mRNA 585 512 458 18.11 15.54 15.32 1.81 1.63 1.63 16.32333333 1.69 66 59 58 518.3333333 61 7.29E-70 -3.096532645 GO:0001669///acrosomal vesicle+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097225///sperm midpiece GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010737///protein kinase A signaling+++GO:0030154///cell differentiation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045920///negative regulation of exocytosis+++GO:1902490///regulation of sperm capacitation 214639 214639 '4930486L24Rik' mRNA 3 7 6 0.13 0.3 0.28 0.76 0.74 0.63 0.236666667 0.71 20 19 16 5.333333333 18.33333333 0.024199067 1.767461791 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0001968///fibronectin binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005518///collagen binding+++GO:0008234///cysteine-type peptidase activity+++GO:0042393///histone binding+++GO:0043394///proteoglycan binding+++GO:0097655///serpin family protein binding GO:0006508///proteolysis+++GO:0006955///immune response+++GO:0016540///protein autoprocessing+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0030574///collagen catabolic process+++GO:0031638///zymogen activation+++GO:0039654///fusion of virus membrane with host endosome membrane+++GO:0046718///viral entry into host cell+++GO:0051603///proteolysis involved in cellular protein catabolic process 214642 214642 'Cped1' mRNA 1707 1663 1602 18.16 17.18 17.74 19.11 18.46 18.89 17.69333333 18.82 2109 2003 1992 1657.333333 2034.666667 7.34E-05 0.284117468 GO:0005783///endoplasmic reticulum GO:0003674///molecular_function GO:0008150///biological_process 214663 214663 'Slc25a29' mRNA 968 964 1058 28.12 27.59 32.6 22.16 22.26 22.35 29.43666667 22.25666667 877 860 856 996.6666667 864.3333333 0.040291492 -0.220270975 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005289///high-affinity arginine transmembrane transporter activity+++GO:0005292///high-affinity lysine transmembrane transporter activity+++GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015227///acyl carnitine transmembrane transporter activity GO:0006844///acyl carnitine transport+++GO:0006865///amino acid transport+++GO:0015822///ornithine transport+++GO:0015879///carnitine transport+++GO:0055085///transmembrane transport+++GO:0089709///L-histidine transmembrane transport+++GO:1902616///acyl carnitine transmembrane transport+++GO:1903400///L-arginine transmembrane transport+++GO:1903401///L-lysine transmembrane transport+++GO:1903826///arginine transmembrane transport+++GO:1990575///mitochondrial L-ornithine transmembrane transport 214669 214669 'L3mbtl2' mRNA 626 678 627 9.77 10.41 10.38 7.37 8.21 8.22 10.18666667 7.933333333 544 591.6 587 643.6666667 574.2 0.152063744 -0.17577545 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007398///ectoderm development+++GO:0010629///negative regulation of gene expression+++GO:0031062///positive regulation of histone methylation+++GO:0035067///negative regulation of histone acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation+++GO:0072089///stem cell proliferation" 214685 214685 'Chadl' mRNA 1282.41 1169.16 639.63 24.66 22.38 12.74 8.1 8.33 9.19 19.92666667 8.54 488.97 488.55 528.42 1030.4 501.98 3.33E-04 -1.036301461 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0098633///collagen fibril binding GO:0032331///negative regulation of chondrocyte differentiation+++GO:1904027///negative regulation of collagen fibril organization 214704 214704 'Iqub' mRNA 576 589 552 8.63 8.72 8.88 0.93 0.66 0.48 8.743333333 0.69 71 50 32 572.3333333 51 7.12E-73 -3.502145646 GO:0001669///acrosomal vesicle+++GO:0031514///motile cilium GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly 214742 214742 'Rcor3' mRNA 811 867 798 12.97 13.37 14.23 11.59 10.99 11.78 13.52333333 11.45333333 858 789 842 825.3333333 829.6666667 0.979619109 -0.004101005 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated" 214763 214763 'Cgas' mRNA 22 23 20 0.29 0.3 0.28 1.74 1.47 1.49 0.29 1.566666667 152 125.02 126 21.66666667 134.34 1.68E-17 2.620360457 04623///Cytosolic DNA-sensing pathway+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0035861///site of double-strand break "GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0061501///cyclic-GMP-AMP synthase activity" GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002637///regulation of immunoglobulin production+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0032479///regulation of type I interferon production+++GO:0032481///positive regulation of type I interferon production+++GO:0038001///paracrine signaling+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045087///innate immune response+++GO:0050776///regulation of immune response+++GO:0050863///regulation of T cell activation+++GO:0051607///defense response to virus+++GO:0071360///cellular response to exogenous dsRNA+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2000774///positive regulation of cellular senescence 214764 214764 'Edrf1' mRNA 420 451 506 4.48 4.75 5.7 3.95 3.67 3.58 4.976666667 3.733333333 427 380 366 459 391 0.107014823 -0.2481569 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function "GO:0045893///positive regulation of transcription, DNA-templated" 214766 214766 'Mmp21' mRNA 2 6 7 0.06 0.18 0.23 0.05 0.11 0.03 0.156666667 0.063333333 2 4 1 5 2.333333333 0.480317379 -1.118329877 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006508///proteolysis+++GO:0007368///determination of left/right symmetry+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0060976///coronary vasculature development+++GO:0061371///determination of heart left/right asymmetry 214779 214779 'Zfp879' mRNA 136 135.95 171 1.8 1.74 2.21 0.88 0.79 0.7 1.916666667 0.79 63 50 55 147.65 56 7.13E-08 -1.41509984 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 214791 214791 'Sertad4' mRNA 40 36 29 0.69 0.63 0.55 0.74 0.82 0.97 0.623333333 0.843333333 49 52 61 35 54 0.124302187 0.61891404 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 214804 214804 'Syde2' mRNA 223 253 257 2.28 2.49 2.77 1.96 1.6 1.36 2.513333333 1.64 210 174 145 244.3333333 176.3333333 0.01492436 -0.486424258 GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0016477///cell migration 214812 214812 'Zfp609' mRNA 332 312 208 2.78 2.58 1.92 1.58 1.76 1.7 2.426666667 1.68 250 217 240 284 235.6666667 0.17206169 -0.273725862 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000291///regulation of myoblast proliferation+++GO:2001224///positive regulation of neuron migration 214854 214854 'Neurl3' mRNA 53 61 40 1.12 1.27 0.91 10.57 9.71 10.7 1.1 10.32666667 578 513 560 51.33333333 550.3333333 3.05E-81 3.413664784 GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 214855 214855 'Arid5a' mRNA 772 784 722 7.23 7.24 7.18 9.54 10.05 9.36 7.216666667 9.65 1175 1208 1116 759.3333333 1166.333333 8.72E-12 0.608649843 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030331///estrogen receptor binding+++GO:0035613///RNA stem-loop binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0050681///androgen receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002062///chondrocyte differentiation+++GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035066///positive regulation of histone acetylation+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071391///cellular response to estrogen stimulus+++GO:2000318///positive regulation of T-helper 17 type immune response+++GO:2000556///positive regulation of T-helper 1 cell cytokine production 214895 214895 'Lman2l' mRNA 2321.87 2415.51 2306.8 46.46 46.94 47.4 38.11 39.15 36.46 46.93333333 37.90666667 2165.75 2150.03 1999.61 2348.06 2105.13 0.023921942 -0.169350912 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0015031///protein transport 214897 214897 'Csnk1g1' mRNA 596 636 630 4.46 4.81 5.03 3.67 3.19 4.16 4.766666667 3.673333333 568 493 564 620.6666667 541.6666667 0.092829487 -0.210055475 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 214899 214899 'Kdm5a' mRNA 2212.73 2255.53 2226.68 12.2 12.64 13.09 10.52 9.67 10.17 12.64333333 10.12 2147.13 1881.19 1972.68 2231.646667 2000.333333 0.028485519 -0.171220509 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032993///protein-DNA complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0034648///histone demethylase activity (H3-dimethyl-K4 specific)+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0032922///circadian regulation of gene expression+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:1901726///negative regulation of histone deacetylase activity" 214901 214901 'Chtf18' mRNA 43 54.22 52.64 0.75 0.94 0.98 2.65 2.91 2.14 0.89 2.566666667 173.24 186.66 135.5 49.95333333 165.1333333 3.52E-11 1.716771369 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031390///Ctf18 RFC-like complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0007140///male meiotic nuclear division+++GO:0032508///DNA duplex unwinding+++GO:0048468///cell development+++GO:0051985///negative regulation of chromosome segregation+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 214917 214917 'Antkmt' mRNA 1860 1779 1735 138.22 126.81 134.7 115.92 121.99 125.97 133.2433333 121.2933333 1794 1853 1904 1791.333333 1850.333333 0.731443548 0.035677531 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity "GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation+++GO:1905273///positive regulation of proton-transporting ATP synthase activity, rotational mechanism+++GO:1905706///regulation of mitochondrial ATP synthesis coupled proton transport" 214922 214922 'Slc39a2' mRNA 20 39 32 0.55 0.99 0.82 1.33 1.34 1.1 0.786666667 1.256666667 63 58 45 30.33333333 55.33333333 0.044769786 0.853866884 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006829///zinc ion transport+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport 214931 214931 'Fbxl16' mRNA 392 429 287 6.12 6.59 4.76 1.91 2.46 2.31 5.823333333 2.226666667 141 177 165 369.3333333 161 1.55E-11 -1.200412583 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 214932 214932 'Hdhd5' mRNA 414 400 353 11.83 11.25 10.56 12.43 12.59 11.64 11.21333333 12.22 497 487 450 389 478 0.02925259 0.287440459 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0046474///glycerophospholipid biosynthetic process 214944 214944 'Mob3b' mRNA 2594 2734.58 2586 23.08 23.95 24.33 9 9.64 10.69 23.78666667 9.776666667 1160.01 1219 1330 2638.193333 1236.336667 4.37E-45 -1.104386318 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0035330///regulation of hippo signaling 214951 214951 'Rhbdl1' mRNA 443 400 132 16.89 15.04 5.34 2.59 3.95 4.25 12.42333333 3.596666667 78 116 124 325 106 0.004696169 -1.601260577 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 214952 214952 'Rhot2' mRNA 864 942 744 16.63 17.85 15.19 15.06 14.05 14.64 16.55666667 14.58333333 900 820 847 850 855.6666667 0.998591786 8.60E-04 04137///Mitophagy - animal GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0007005///mitochondrion organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0010821///regulation of mitochondrion organization+++GO:0019725///cellular homeostasis+++GO:0047497///mitochondrion transport along microtubule+++GO:0097345///mitochondrial outer membrane permeabilization 214968 214968 'Sema6d' mRNA 2189 2334 1749 17.68 18.3 15.38 7.13 7.42 7.15 17.12 7.233333333 983 1014 961 2090.666667 986 1.19E-34 -1.09035247 04360///Axon guidance GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0021591///ventricular system development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 214987 214987 'Chtf8' mRNA 351.41 366.36 164.08 6.6 6.77 3.27 3.57 2.48 4.07 5.546666667 3.373333333 218.92 148.33 241.79 293.95 203.0133333 0.043512558 -0.535686772 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031390///Ctf18 RFC-like complex GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0032508///DNA duplex unwinding+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 215001 215001 'Wfikkn1' mRNA 80 54 57 1.76 1.17 1.33 0.71 1.11 0.73 1.42 0.85 37 57 37 63.66666667 43.66666667 0.168336297 -0.55105761 GO:0005576///extracellular region GO:0004857///enzyme inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0048019///receptor antagonist activity+++GO:0050431///transforming growth factor beta binding GO:0001501///skeletal system development+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0043392///negative regulation of DNA binding+++GO:0045861///negative regulation of proteolysis+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0060021///roof of mouth development+++GO:2000272///negative regulation of signaling receptor activity 215008 215008 'Vezt' mRNA 767 831 769 3.31 3.52 3.62 2.98 3.04 3.16 3.483333333 3.06 787 788 807 789 794 0.994543387 -0.00206667 GO:0001669///acrosomal vesicle+++GO:0002142///stereocilia ankle link complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0060171///stereocilium membrane GO:0005515///protein binding+++GO:0017022///myosin binding GO:0007275///multicellular organism development+++GO:0043009///chordate embryonic development+++GO:0098609///cell-cell adhesion 215015 215015 'Fam20b' mRNA 948 821 754 11.61 9.96 9.84 10.02 9.61 9.91 10.47 9.846666667 924 873 896 841 897.6666667 0.493035609 0.084266493 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0046872///metal ion binding" GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030166///proteoglycan biosynthetic process 215031 215031 'Vgll2' mRNA 1 2 2 0.04 0.07 0.08 0 0.03 0.03 0.063333333 0.02 0 1 1 1.666666667 0.666666667 0.646159787 -1.328759756 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II" 215051 215051 'Bud13' mRNA 388 360 400 9.9 9.05 10.83 8.9 9.09 7.8 9.926666667 8.596666667 401 400 340 382.6666667 380.3333333 0.900494927 -0.023170751 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0070274///RES complex+++GO:0071005///U2-type precatalytic spliceosome "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 215061 215061 'Trim50' mRNA 4 9 4 0.12 0.27 0.17 0 0.05 0.07 0.186666667 0.04 0 2 2 5.666666667 1.333333333 0.193016783 -2.078044999 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0070201///regulation of establishment of protein localization 215085 215085 'Slc35f1' mRNA 93 107 87 1 1.13 0.99 0.53 0.51 0.6 1.04 0.546666667 57 53 62 95.66666667 57.33333333 0.010222762 -0.747931328 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0008150///biological_process+++GO:0055085///transmembrane transport 215090 215090 'Maneal' mRNA 196 190 153 4.8 4.67 4.07 0.72 0.88 0.54 4.513333333 0.713333333 33 36 22 179.6666667 30.33333333 4.27E-21 -2.573861222 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004559///alpha-mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0008150///biological_process 215113 215113 'Slc43a2' mRNA 702 691 581 5.87 5.9 5.27 10.92 9.56 9.52 5.68 10 1565 1267 1326 658 1386 1.12E-27 1.064146679 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0051956///negative regulation of amino acid transport+++GO:0055085///transmembrane transport+++GO:0060358///negative regulation of leucine import+++GO:1902475///L-alpha-amino acid transmembrane transport 215114 215114 'Hip1' mRNA 3301.97 3430.51 3181.18 18.13 18.91 19.08 12.49 11.38 11.7 18.70666667 11.85666667 2578.01 2266.76 2339.52 3304.553333 2394.763333 1.82E-13 -0.476820707 05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0098978///glutamatergic synapse "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0030276///clathrin binding+++GO:0032051///clathrin light chain binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0042803///protein homodimerization activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007015///actin filament organization+++GO:0030154///cell differentiation+++GO:0042981///regulation of apoptotic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048268///clathrin coat assembly+++GO:0050821///protein stabilization+++GO:0072583///clathrin-dependent endocytosis+++GO:0097190///apoptotic signaling pathway+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway 215160 215160 'Rhbdd2' mRNA 2776.72 2994.59 2782.12 35.6 37.79 37.83 21.2 20.8 18.95 37.07333333 20.31666667 1901.28 1822 1646.59 2851.143333 1789.956667 9.36E-21 -0.683639982 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004252///serine-type endopeptidase activity GO:0006508///proteolysis 215193 215193 'Utp25' mRNA 156 130 113.48 2.15 1.88 1.72 2.1 0.97 1.43 1.916666667 1.5 159 86 126 133.16 123.6666667 0.73660925 -0.117688779 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome GO:0019843///rRNA binding+++GO:0034511///U3 snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0007275///multicellular organism development+++GO:0030163///protein catabolic process+++GO:0031648///protein destabilization+++GO:0040019///positive regulation of embryonic development+++GO:0048568///embryonic organ development+++GO:1902570///protein localization to nucleolus" 215194 215194 'Kri1' mRNA 523.39 496.19 525.67 11.19 10.44 11.92 10.61 9.77 10.77 11.18333333 10.38333333 571.12 513.49 561.02 515.0833333 548.5433333 0.606866237 0.077554249 GO:0005730///nucleolus+++GO:0030686///90S preribosome "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 215201 215201 'Trmt2b' mRNA 666 774 666 12.3 13.98 12.51 9.96 9.42 11.47 12.93 10.28333333 606 561 699 702 622 0.156875958 -0.184942307 GO:0005739///mitochondrion GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0030697///S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity GO:0001510///RNA methylation+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:0008150///biological_process+++GO:0030488///tRNA methylation+++GO:0032259///methylation 215210 215210 'Tmem120a' mRNA 358 317 363 17 14.86 18.29 28.42 30.79 29.9 16.71666667 29.70333333 687 726 699 346 704 1.42E-16 1.011333374 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0045444///fat cell differentiation+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051260///protein homooligomerization+++GO:0051291///protein heterooligomerization 215243 215243 'Traf3ip3' mRNA 25.52 26.63 20.8 0.68 0.7 0.59 2.5 3.32 2.66 0.656666667 2.826666667 107.65 139.81 111.02 24.31666667 119.4933333 4.05E-13 2.32381641 GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 215257 215257 'Il1f9' mRNA 88.02 73.45 76.3 3.12 2.56 2.87 2.85 1.96 2.98 2.85 2.596666667 92.53 62 93.56 79.25666667 82.69666667 0.90303828 0.045552511 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045087///innate immune response+++GO:0045662///negative regulation of myoblast differentiation+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901740///negative regulation of myoblast fusion 215280 215280 'Wipf1' mRNA 308 347 231 3.42 3.87 2.61 6.3 5.67 5.95 3.3 5.973333333 638 553 594 295.3333333 595 3.43E-13 1.004184238 04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0008154///actin polymerization or depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030048///actin filament-based movement+++GO:0046827///positive regulation of protein export from nucleus+++GO:0051707///response to other organism 215303 215303 'Camk1g' mRNA 252 262 245 5.71 5.8 5.89 2.05 2.38 2.22 5.8 2.216666667 105 119 110 253 111.3333333 1.04E-10 -1.194681023 04020///Calcium signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++05214///Glioma GO:0000139///Golgi membrane+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005954///calcium- and calmodulin-dependent protein kinase complex+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0043005///neuron projection GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation 215332 215332 'Slc36a3' mRNA 4 2 2 0.22 0.11 0.12 0 0 0.04 0.15 0.013333333 0 0 1 2.666666667 0.333333333 0.24336858 -2.902148968 04974///Protein digestion and absorption GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005280///amino acid:proton symporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0015808///L-alanine transport+++GO:0015816///glycine transport+++GO:0035524///proline transmembrane transport+++GO:1902600///proton transmembrane transport 215335 215335 'Slc36a1' mRNA 143.13 193 146.04 1.45 1.92 1.57 2.71 2.13 2.41 1.646666667 2.416666667 308.12 237.29 265.42 160.7233333 270.2766667 9.01E-05 0.738043514 04974///Protein digestion and absorption GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005280///amino acid:proton symporter activity+++GO:0005302///L-tyrosine transmembrane transporter activity+++GO:0005368///taurine transmembrane transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022858///alanine transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015734///taurine transport+++GO:0015804///neutral amino acid transport+++GO:0015808///L-alanine transport+++GO:0015816///glycine transport+++GO:0015824///proline transport+++GO:0015828///tyrosine transport+++GO:0032328///alanine transport+++GO:0035524///proline transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:1902600///proton transmembrane transport 215351 215351 'Senp6' mRNA 672 634 602 7.3 6.71 6.92 6.79 5.48 5.89 6.976666667 6.053333333 722 567 615 636 634.6666667 0.917128784 -0.015894419 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0016925///protein sumoylation+++GO:0016926///protein desumoylation+++GO:0070646///protein modification by small protein removal+++GO:0090169///regulation of spindle assembly+++GO:0090234///regulation of kinetochore assembly 215378 215378 'Brinp3' mRNA 1 2 3 0.02 0.04 0.06 0 0.02 0 0.04 0.006666667 0 1 0 2 0.333333333 0.370649537 -2.508800057 GO:0005576///extracellular region+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007399///nervous system development+++GO:0045666///positive regulation of neuron differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0071300///cellular response to retinoic acid 215384 215384 'Fcgbp' mRNA 147.77 130 136.77 0.98 0.85 0.96 0.36 0.29 0.29 0.93 0.313333333 63.01 48.62 48 138.18 53.21 9.19E-08 -1.391543875 GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005515///protein binding GO:0008150///biological_process 215387 215387 'Ncaph' mRNA 14 13 33 0.29 0.26 0.72 4.79 5.03 4.52 0.423333333 4.78 268 275 245 20 262.6666667 3.87E-36 3.69315518 GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0044547///DNA topoisomerase binding+++GO:0072587///DNA topoisomerase (ATP-hydrolyzing) activator activity GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0007143///female meiotic nuclear division+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0045132///meiotic chromosome segregation+++GO:0051301///cell division+++GO:0051309///female meiosis chromosome separation 215418 215418 'Csrnp1' mRNA 157 126 93 2.81 2.22 1.79 3.89 3.81 4.66 2.273333333 4.12 246 236 282 125.3333333 254.6666667 7.88E-07 1.01778108 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0009791///post-embryonic development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis" 215436 215436 'Slc35e3' mRNA 396 352 396 6.18 5.41 6.56 6.15 5.24 6.12 6.05 5.836666667 453 377 437 381.3333333 422.3333333 0.42796645 0.132080318 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005338///nucleotide-sugar transmembrane transporter activity+++GO:0015297///antiporter activity GO:0015931///nucleobase-containing compound transport+++GO:0055085///transmembrane transport+++GO:1901264///carbohydrate derivative transport 215445 215445 'Rab11fip3' mRNA 1623 1506 1607 19.13 16.6 20.74 8.52 6.54 7.27 18.82333333 7.443333333 732 573 603 1578.666667 636 9.22E-40 -1.327252999 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051959///dynein light intermediate chain binding GO:0007049///cell cycle+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division+++GO:0061512///protein localization to cilium+++GO:0070164///negative regulation of adiponectin secretion 215446 215446 'Entpd3' mRNA 994 1001 1028 17.35 17.39 19.07 17.83 19.21 18.01 17.93666667 18.35 1159 1225 1123 1007.666667 1169 0.041864 0.201609762 00230///Purine metabolism+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005524///ATP binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0045134///uridine-diphosphatase activity+++GO:0102485///dATP phosphohydrolase activity+++GO:0102486///dCTP phosphohydrolase activity+++GO:0102487///dUTP phosphohydrolase activity+++GO:0102488///dTTP phosphohydrolase activity+++GO:0102489///GTP phosphohydrolase activity+++GO:0102490///8-oxo-dGTP phosphohydrolase activity+++GO:0102491///dGTP phosphohydrolase activity GO:0009134///nucleoside diphosphate catabolic process+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0016311///dephosphorylation 215449 215449 'Rap1b' mRNA 849 854 540 25.04 24.82 16.9 42.95 39.51 46.24 22.25333333 42.9 1674 1503 1744 747.6666667 1640.333333 1.31E-20 1.130295402 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04934///Cushing syndrome+++04972///Pancreatic secretion+++05211///Renal cell carcinoma+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0008283///cell proliferation+++GO:0009743///response to carbohydrate+++GO:0032486///Rap protein signal transduction+++GO:0033625///positive regulation of integrin activation+++GO:0035690///cellular response to drug+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0061028///establishment of endothelial barrier+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0071407///cellular response to organic cyclic compound+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:1901888///regulation of cell junction assembly+++GO:2000114///regulation of establishment of cell polarity+++GO:2000301///negative regulation of synaptic vesicle exocytosis 215456 215456 'Gpat2' mRNA 21 15 14 0.42 0.3 0.29 0.15 0.15 0.11 0.336666667 0.136666667 9 8 6 16.66666667 7.666666667 0.144440444 -1.129890271 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0004366///glycerol-3-phosphate O-acyltransferase activity+++GO:0005515///protein binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0102420///sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity" GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0044255///cellular lipid metabolic process+++GO:1990511///piRNA biosynthetic process 215467 215467 'Gm4791' mRNA 242.77 251.01 266 15.13 15.46 17.58 3.08 4.24 2.81 16.05666667 3.376666667 56.69 76 50 253.26 60.89666667 1.26E-20 -2.072792457 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 215474 215474 'Sec22c' mRNA 633 695 439 5.9 6.39 4.36 2.83 2.99 2.82 5.55 2.88 348 359 340 589 349 2.96E-07 -0.757847571 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 215476 215476 'Prr14l' mRNA 1022 1085 986 5.4 5.65 5.45 5.58 5.04 5.49 5.5 5.37 1250 1024 1179 1031 1151 0.154540741 0.146531323 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 215493 215493 'A3galt2' mRNA 6 13 7 0.1 0.21 0.12 0.03 0.07 0.26 0.143333333 0.12 2 5 18 8.666666667 8.333333333 0.970280639 -0.053846527 00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0032580///Golgi cisterna membrane "GO:0001962///alpha-1,3-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0046872///metal ion binding+++GO:0047276///N-acetyllactosaminide 3-alpha-galactosyltransferase activity" GO:0005975///carbohydrate metabolic process+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0030259///lipid glycosylation+++GO:0071287///cellular response to manganese ion 215494 215494 'Pomgnt2' mRNA 1613 1758 1603 37.87 40.68 39.89 19.64 17.77 17.22 39.48 18.21 963 851 816 1658 876.6666667 7.14E-28 -0.931603755 00515///Mannose type O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0097363///protein O-GlcNAc transferase activity" GO:0001764///neuron migration+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0035269///protein O-linked mannosylation 215512 215512 'Fam117a' mRNA 244 318 217 5.35 6.67 5.27 3.69 3.54 3.31 5.763333333 3.513333333 197 174 180 259.6666667 183.6666667 0.007313823 -0.506642792 GO:0003674///molecular_function GO:0008150///biological_process 215615 215615 'Rnpep' mRNA 1588 1678 1604 38.92 40.58 41.73 61.3 59.29 60.15 40.41 60.24666667 2857 2709 2723 1623.333333 2763 3.31E-29 0.755004342 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0030141///secretory granule+++GO:0043005///neuron projection GO:0004177///aminopeptidase activity+++GO:0005507///copper ion binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0050897///cobalt ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0045776///negative regulation of blood pressure 215627 215627 'Zbtb8b' mRNA 360 374 344 4.36 4.47 4.46 7.36 6.61 7.61 4.43 7.193333333 700 611 702 359.3333333 671 1.62E-14 0.889264077 GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 215632 215632 'Psd4' mRNA 32 58 61 0.3 0.56 0.66 3.8 2.93 3.16 0.506666667 3.296666667 436 331 349 50.33333333 372 3.50E-37 2.86755231 04144///Endocytosis+++04361///Axon regeneration GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity 215653 215653 'Rassf2' mRNA 425 395 354 4.82 4.41 4.2 11.93 11.5 12.85 4.476666667 12.09333333 1214 1136 1275 391.3333333 1208.333333 1.40E-58 1.616613119 04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex" GO:0004672///protein kinase activity+++GO:0005515///protein binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0038168///epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0045667///regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0046849///bone remodeling+++GO:0048872///homeostasis of number of cells+++GO:0050821///protein stabilization+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 215690 215690 'Nav1' mRNA 913.82 899.06 812.8 3.48 3.38 3.31 3.39 3.04 3.83 3.39 3.42 1039.14 901.29 1123.11 875.2266667 1021.18 0.049135023 0.212351845 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0043194///axon initial segment GO:0001578///microtubule bundle formation+++GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation 215693 215693 'Zmat1' mRNA 398 434 398 6.18 6.63 6.55 2.54 2.57 3.16 6.453333333 2.756666667 188 186 227 410 200.3333333 4.61E-12 -1.044101807 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding 215705 215705 'Arrdc1' mRNA 2164 2108 1992 73.88 70.72 71.89 57.54 57.01 53.46 72.16333333 56.00333333 1922 1852 1748 2088 1840.666667 0.009447729 -0.193273578 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:1903561///extracellular vesicle "GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination+++GO:1990763///arrestin family protein binding" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006858///extracellular transport+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0140112///extracellular vesicle biogenesis 215707 215707 'Ccdc92' mRNA 1114 1113 674 27.78 27.33 18.25 7.61 12.68 11.44 24.45333333 10.57666667 351 571 511 967 477.6666667 0.001421638 -1.013110119 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding GO:0008150///biological_process 215708 215708 'Miga1' mRNA 595 686 358 5.55 5.97 3.24 2.35 2.15 2.2 4.92 2.233333333 304 273.57 276 546.3333333 284.5233333 1.41E-07 -0.942336866 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0008053///mitochondrial fusion 215723 215723 'Mfsd6l' mRNA 317 337 295 8.73 9.15 8.62 3.95 3.34 3.22 8.833333333 3.503333333 165 136 130 316.3333333 143.6666667 8.06E-12 -1.150315713 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 215748 215748 'Cnksr3' mRNA 240 244 137 3.91 3.79 2.43 2.2 1.92 2.5 3.376666667 2.206666667 146 125 165 207 145.3333333 0.034385963 -0.511579551 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051393///alpha-actinin binding+++GO:0060090///molecular adaptor activity GO:0007165///signal transduction+++GO:0009966///regulation of signal transduction+++GO:0010765///positive regulation of sodium ion transport+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 215751 215751 'Ginm1' mRNA 1301 1329 1305 49.01 49.37 52.15 70.33 68.84 68.05 50.17666667 69.07333333 2145 2049 2008 1311.666667 2067.333333 1.81E-18 0.643811736 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 215772 215772 'Adgb' mRNA 195 171 187 1.93 1.67 1.97 0.4 0.44 0.42 1.856666667 0.42 46 49 47 184.3333333 47.33333333 1.90E-16 -1.974408601 GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding GO:0006508///proteolysis 215789 215789 'Phactr2' mRNA 2888 2791 2939 18.07 17.19 19.58 10.71 11.37 11.66 18.28 11.24666667 1975 2047 2085 2872.666667 2035.666667 1.59E-11 -0.509990541 GO:0005575///cellular_component GO:0003779///actin binding+++GO:0004864///protein phosphatase inhibitor activity GO:0030036///actin cytoskeleton organization+++GO:0043086///negative regulation of catalytic activity 215798 215798 'Adgrg6' mRNA 2458 2473 2035 19.27 19.21 17.13 11.47 9.11 10.85 18.53666667 10.47666667 1682 1320 1550 2322 1517.333333 9.42E-13 -0.623782235 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0043236///laminin binding+++GO:0050840///extracellular matrix binding GO:0007005///mitochondrion organization+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0014037///Schwann cell differentiation+++GO:0019933///cAMP-mediated signaling+++GO:0022011///myelination in peripheral nervous system+++GO:0042552///myelination+++GO:0060347///heart trabecula formation 215814 215814 'Ccdc28a' mRNA 348 350 291 16.5 15.87 14.22 11.76 9.44 11.77 15.53 10.99 279 229 269 329.6666667 259 0.025032261 -0.357925134 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 215819 215819 'Nhsl1' mRNA 2195.69 2185.81 1970.04 12.32 12.28 11.83 15.44 13.43 14.18 12.14333333 14.35 2960.38 2553.08 2612.16 2117.18 2708.54 1.23E-06 0.344143267 GO:0003674///molecular_function GO:0030154///cell differentiation 215821 215821 'Arfgef3' mRNA 455 408 356 2.91 2.57 2.42 0.81 0.71 0.95 2.633333333 0.823333333 146 124 165 406.3333333 145 8.47E-20 -1.495827967 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity GO:0010923///negative regulation of phosphatase activity+++GO:0030036///actin cytoskeleton organization+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity 215854 215854 'Taar5' mRNA 0 2 1 0 0.12 0.07 0 0 0 0.063333333 0 0 0 0 1 0 0.607488248 -2.448949589 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001594///trace-amine receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008227///G protein-coupled amine receptor activity+++GO:1990081///trimethylamine receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007606///sensory perception of chemical stimulus+++GO:0007610///behavior+++GO:0007617///mating behavior+++GO:0035176///social behavior 215900 215900 'Calhm6' mRNA 39 35 40 2.26 2.01 2.46 10.72 9.39 9.84 2.243333333 9.983333333 212 181 188 38 193.6666667 2.98E-21 2.335194622 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005261///cation channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 215928 215928 'Mfsd4b5' mRNA 4 11.01 4 0.07 0.2 0.08 0.16 0.15 0.09 0.116666667 0.133333333 10 9 6.02 6.336666667 8.34 0.749855753 0.395714887 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005355///glucose transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:1904659///glucose transmembrane transport 215929 215929 'Mfsd4b1' mRNA 18 28 27 0.37 0.57 0.59 0.21 0.09 0.32 0.51 0.206666667 11 5 17 24.33333333 11 0.087482612 -1.162684761 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005355///glucose transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 215951 215951 'Afg1l' mRNA 274 278 258 6.15 6.17 6.1 5.19 4.88 5.47 6.14 5.18 266 246 272 270 261.3333333 0.781216872 -0.058352351 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity "GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0007005///mitochondrion organization+++GO:0035694///mitochondrial protein catabolic process" 215999 215999 'Mcu' mRNA 578 544 367 11.07 10.26 7.44 6.12 4.62 6.03 9.59 5.59 367 272 352 496.3333333 330.3333333 4.10E-04 -0.592899427 04020///Calcium signaling pathway+++04218///Cellular senescence+++04621///NOD-like receptor signaling pathway+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0034704///calcium channel complex+++GO:1990246///uniplex complex GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015292///uniporter activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0019722///calcium-mediated signaling+++GO:0032024///positive regulation of insulin secretion+++GO:0036444///calcium import into the mitochondrion+++GO:0042593///glucose homeostasis+++GO:0051259///protein complex oligomerization+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0070588///calcium ion transmembrane transport+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090527///actin filament reorganization 216001 216001 'Micu1' mRNA 2064 2138 2022 47.53 48.15 49.39 43.06 43.49 41.38 48.35666667 42.64333333 2158 2103 1989 2074.666667 2083.333333 0.953668173 -0.005773824 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0034704///calcium channel complex+++GO:1990246///uniplex complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051260///protein homooligomerization+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0070509///calcium ion import+++GO:1900069///regulation of cellular hyperosmotic salinity response 216011 216011 'Lrrc20' mRNA 353.01 342 295 7 6.64 6.01 2.74 3.63 3.37 6.55 3.246666667 166 214 202 330.0033333 194 4.27E-06 -0.773344023 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 216019 216019 'Hkdc1' mRNA 2 5 6 0.04 0.09 0.1 0.32 0.24 0.09 0.076666667 0.216666667 20 14 6 4.333333333 13.33333333 0.102249114 1.595964182 "00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++00524///Neomycin, kanamycin and gentamicin biosynthesis+++01200///Carbon metabolism+++01250///Biosynthesis of nucleotide sugars+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++04930///Type II diabetes mellitus+++04973///Carbohydrate digestion and absorption+++05131///Shigellosis+++05230///Central carbon metabolism in cancer" GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane "GO:0000166///nucleotide binding+++GO:0004340///glucokinase activity+++GO:0004396///hexokinase activity+++GO:0005524///ATP binding+++GO:0005536///glucose binding+++GO:0008865///fructokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019158///mannokinase activity" GO:0001678///cellular glucose homeostasis+++GO:0005975///carbohydrate metabolic process+++GO:0006096///glycolytic process+++GO:0016310///phosphorylation+++GO:0019318///hexose metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0051156///glucose 6-phosphate metabolic process 216021 216021 'Stox1' mRNA 839 812 607 16.66 15.6 12.29 2.6 4.66 3.53 14.85 3.596666667 173 257 172 752.6666667 200.6666667 1.23E-31 -1.909802309 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010821///regulation of mitochondrion organization+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051301///cell division+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0071500///cellular response to nitrosative stress+++GO:1901858///regulation of mitochondrial DNA metabolic process+++GO:1902882///regulation of response to oxidative stress+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:1904120///positive regulation of otic vesicle morphogenesis 216028 216028 'Lrrtm3' mRNA 17 21 13 0.24 0.29 0.19 0.22 0.15 0.28 0.24 0.216666667 18 12 22 17 17.33333333 0.984360794 0.021701536 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0051965///positive regulation of synapse assembly+++GO:0099054///presynapse assembly+++GO:1902004///positive regulation of amyloid-beta formation 216033 216033 'Ctnna3' mRNA 173 127 175 2.05 1.48 2.14 0.34 0.29 0.42 1.89 0.35 37 31 40 158.3333333 36 2.08E-14 -2.154736861 04390///Hippo signaling pathway+++04520///Adherens junction+++04670///Leukocyte transendothelial migration+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++05226///Gastric cancer+++05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005916///fascia adherens+++GO:0030027///lamellipodium GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0045296///cadherin binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090136///epithelial cell-cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential 216036 216036 'Gm4796' mRNA 0 0 2.01 0 0 0.25 0 0 0.23 0.083333333 0.076666667 0 0 2.14 0.67 0.713333333 0.994751757 -0.070497437 216049 216049 'Zfp365' mRNA 212 161 138 2.68 2 1.85 1.22 0.92 1.04 2.176666667 1.06 111 82 92 170.3333333 95 4.05E-04 -0.851595515 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0000281///mitotic cytokinesis+++GO:0000723///telomere maintenance+++GO:0007399///nervous system development+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010975///regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0021687///cerebellar molecular layer morphogenesis+++GO:0033566///gamma-tubulin complex localization+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0060997///dendritic spine morphogenesis+++GO:0110026///regulation of DNA strand resection involved in replication fork processing+++GO:0140059///dendrite arborization 216080 216080 'Ube2d1' mRNA 590 521 438 24.54 21.47 19.82 20.34 19.26 20.19 21.94333333 19.93 561 520 541 516.3333333 540.6666667 0.730679631 0.058097181 04013///MAPK signaling pathway - fly+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:1902916///positive regulation of protein polyubiquitination 216119 216119 'Ybey' mRNA 150.75 158.53 173.05 1.79 1.85 2.18 1.45 1.17 1.35 1.94 1.323333333 140.25 111.25 126.79 160.7766667 126.0966667 0.115012085 -0.367895653 GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0004222///metalloendopeptidase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006364///rRNA processing+++GO:0006508///proteolysis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 216131 216131 'Trappc10' mRNA 320.94 288.85 227.77 3.22 2.91 2.41 2.6 2.77 2.4 2.846666667 2.59 302.46 333.18 287.09 279.1866667 307.5766667 0.488522293 0.13697169 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030008///TRAPP complex+++GO:1990071///TRAPPII protein complex GO:0003674///molecular_function GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport+++GO:0048193///Golgi vesicle transport 216134 216134 'Pdxk' mRNA 3440.55 3477.01 3316 36.06 35.83 36.86 45.76 40.95 42.8 36.25 43.17 5027 4395 4554 3411.186667 4658.666667 1.45E-12 0.43695818 00750///Vitamin B6 metabolism+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0008478///pyridoxal kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0030955///potassium ion binding+++GO:0031402///sodium ion binding+++GO:0031403///lithium ion binding+++GO:0036094///small molecule binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070280///pyridoxal binding+++GO:0097159///organic cyclic compound binding GO:0009443///pyridoxal 5'-phosphate salvage+++GO:0016310///phosphorylation+++GO:0042823///pyridoxal phosphate biosynthetic process+++GO:0043066///negative regulation of apoptotic process 216136 216136 'Ilvbl' mRNA 1212 1255 1207 29.57 30.33 31.14 29 28.78 28.78 30.34666667 28.85333333 1353 1310 1302 1224.666667 1321.666667 0.292926237 0.097910302 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005948///acetolactate synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0003984///acetolactate synthase activity+++GO:0016829///lyase activity+++GO:0030976///thiamine pyrophosphate binding+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding GO:0001561///fatty acid alpha-oxidation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009097///isoleucine biosynthetic process+++GO:0009099///valine biosynthetic process 216148 216148 'Shc2' mRNA 54 60 23 0.74 0.8 0.33 0.52 0.45 0.72 0.623333333 0.563333333 44 37 59 45.66666667 46.66666667 0.951371097 0.03524613 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05100///Bacterial invasion of epithelial cells+++05214///Glioma+++05220///Chronic myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005886///plasma membrane GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding GO:0000187///activation of MAPK activity+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade 216150 216150 'Cdc34' mRNA 519 465 490 29.38 25.9 29.37 33.74 36.9 37.73 28.21666667 36.12333333 682 728 741 491.3333333 717 3.54E-06 0.533472701 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0035458///cellular response to interferon-beta+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0070936///protein K48-linked ubiquitination+++GO:0090261///positive regulation of inclusion body assembly 216151 216151 'Polrmt' mRNA 559 572 526 8.03 8.07 8.01 7.55 6.75 6.3 8.036666667 6.866666667 604 529 488 552.3333333 540.3333333 0.788386183 -0.043794607 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0032991///protein-containing complex+++GO:0034245///mitochondrial DNA-directed RNA polymerase complex+++GO:0042645///mitochondrial nucleoid GO:0001018///mitochondrial promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0043565///sequence-specific DNA binding "GO:0006351///transcription, DNA-templated+++GO:0006390///mitochondrial transcription" 216152 216152 'Plppr3' mRNA 579.39 647.82 470.47 10.57 11.65 8.99 13.17 10.48 13.19 10.40333333 12.28 804.37 618.55 772.54 565.8933333 731.82 0.006048259 0.363125888 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030246///carbohydrate binding+++GO:0042577///lipid phosphatase activity GO:0002215///defense response to nematode+++GO:0002376///immune system process+++GO:0006644///phospholipid metabolic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0016311///dephosphorylation+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042742///defense response to bacterium+++GO:0046839///phospholipid dephosphorylation 216154 216154 'Med16' mRNA 1399.78 1397.38 801.38 24.68 24.36 14.97 8.75 11.07 10.1 21.33666667 9.973333333 560.76 702.33 637.8 1199.513333 633.63 5.02E-04 -0.918574292 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003713///transcription coactivator activity+++GO:0003824///catalytic activity+++GO:0046966///thyroid hormone receptor binding "GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 216156 216156 'Wdr18' mRNA 816 900 874 15.19 16.47 17.24 20.67 20.48 19.19 16.3 20.11333333 1279 1237 1150 863.3333333 1222 1.71E-07 0.488346533 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005656///nuclear pre-replicative complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0097344///Rix1 complex GO:0003674///molecular_function GO:0006364///rRNA processing+++GO:0007275///multicellular organism development+++GO:0030174///regulation of DNA-dependent DNA replication initiation 216157 216157 'Tmem259' mRNA 455 462 474 11.77 11.82 13.11 12.7 13.17 13.96 12.23333333 13.27666667 564 568 596 463.6666667 576 0.01492436 0.300258996 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0034976///response to endoplasmic reticulum stress+++GO:1901215///negative regulation of neuron death+++GO:1904294///positive regulation of ERAD pathway 216161 216161 'Sbno2' mRNA 997 1007 1022 14.13 14.24 14.93 41.85 38.01 40.57 14.43333333 40.14333333 3619 3311 3475 1008.666667 3468.333333 2.50E-137 1.768463507 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0042393///histone binding "GO:0001503///ossification+++GO:0002281///macrophage activation involved in immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030316///osteoclast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0061430///bone trabecula morphogenesis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071348///cellular response to interleukin-11+++GO:0071354///cellular response to interleukin-6+++GO:0072674///multinuclear osteoclast differentiation+++GO:0072675///osteoclast fusion+++GO:1990830///cellular response to leukemia inhibitory factor" 216166 216166 'Plk5' mRNA 380 365 343 10.41 9.94 9.71 2.6 3.22 2.6 10.02 2.806666667 111 132 104 362.6666667 115.6666667 1.50E-22 -1.65849866 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0002357///defense response to tumor cell+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0032465///regulation of cytokinesis+++GO:0042981///regulation of apoptotic process+++GO:0044819///mitotic G1/S transition checkpoint+++GO:0051301///cell division+++GO:0071363///cellular response to growth factor stimulus+++GO:0090166///Golgi disassembly+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 216169 216169 'Abhd17a' mRNA 221 244.01 206 8.68 9.34 8.29 9.48 7.64 10.44 8.77 9.186666667 282 220 297 223.67 266.3333333 0.214076027 0.240860585 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055038///recycling endosome membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099031///anchored component of postsynaptic density membrane+++GO:0099033///anchored component of postsynaptic recycling endosome membrane GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity GO:0002084///protein depalmitoylation+++GO:0072657///protein localization to membrane+++GO:0099175///regulation of postsynapse organization+++GO:1902817///negative regulation of protein localization to microtubule+++GO:1905668///positive regulation of protein localization to endosome 216177 216177 'AU041133' mRNA 317 266 375 6.3 5.34 7.84 3.81 3.07 3.38 6.493333333 3.42 218 174 185 319.3333333 192.3333333 8.35E-05 -0.752485413 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 216188 216188 'Aldh1l2' mRNA 148.02 148.99 150.72 0.9 0.92 1.02 1.3 1.15 1.34 0.946666667 1.263333333 196 182.98 205 149.2433333 194.66 0.065911653 0.373647673 00670///One carbon pool by folate GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0003824///catalytic activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016155///formyltetrahydrofolate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016742///hydroxymethyl-, formyl- and related transferase activity" GO:0006730///one-carbon metabolic process+++GO:0009058///biosynthetic process+++GO:0009258///10-formyltetrahydrofolate catabolic process 216190 216190 'Appl2' mRNA 2046.53 2127.65 2182.56 37.33 38.45 42.25 19.45 19.9 19.76 39.34333333 19.70333333 1231.18 1226.46 1197.41 2118.913333 1218.35 2.77E-24 -0.811982062 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031982///vesicle+++GO:0032009///early phagosome+++GO:0032587///ruffle membrane+++GO:0036186///early phagosome membrane+++GO:0042995///cell projection+++GO:0044354///macropinosome+++GO:0045335///phagocytic vesicle GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding "GO:0002024///diet induced thermogenesis+++GO:0006606///protein import into nucleus+++GO:0007049///cell cycle+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0009631///cold acclimation+++GO:0010762///regulation of fibroblast migration+++GO:0023052///signaling+++GO:0033211///adiponectin-activated signaling pathway+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042593///glucose homeostasis+++GO:0045088///regulation of innate immune response+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0046325///negative regulation of glucose import+++GO:0050768///negative regulation of neurogenesis+++GO:0051289///protein homotetramerization+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900077///negative regulation of cellular response to insulin stimulus+++GO:1905303///positive regulation of macropinocytosis+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:2000178///negative regulation of neural precursor cell proliferation" 216197 216197 'Ckap4' mRNA 361 377 286 6.82 7.01 5.73 11.16 9.01 11.42 6.52 10.53 680 536 674 341.3333333 630 6.48E-11 0.875408606 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm GO:0008150///biological_process 216198 216198 'Tcp11l2' mRNA 1463 1508 1328 34.08 34.59 32.82 23.7 25.39 24.15 33.83 24.41333333 1170 1224 1154 1433 1182.666667 5.48E-04 -0.286480249 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007165///signal transduction 216225 216225 'Slc5a8' mRNA 7 0 3 0.07 0 0.03 0.04 0.03 0.14 0.033333333 0.07 5 3 16 3.333333333 8 0.38156525 1.249486076 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005343///organic acid:sodium symporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015552///propionate transmembrane transporter activity+++GO:0015636///short-chain fatty acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0140161///monocarboxylate:sodium symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006915///apoptotic process+++GO:0015718///monocarboxylic acid transport+++GO:0015730///propanoate transport+++GO:0015913///short-chain fatty acid import+++GO:0035873///lactate transmembrane transport+++GO:0055085///transmembrane transport+++GO:1903825///organic acid transmembrane transport 216227 216227 'Slc17a8' mRNA 543 594 492 6.58 7.05 6.32 0.79 0.57 0.44 6.65 0.6 75 53 40 543 56 5.74E-69 -3.288743409 04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++05033///Nicotine addiction GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite+++GO:0097451///glial limiting end-foot+++GO:1990030///pericellular basket GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity "GO:0003407///neural retina development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0006836///neurotransmitter transport+++GO:0007420///brain development+++GO:0007605///sensory perception of sound+++GO:0015813///L-glutamate transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050803///regulation of synapse structure or activity+++GO:0055085///transmembrane transport+++GO:0090102///cochlea development+++GO:0098700///neurotransmitter loading into synaptic vesicle" 216233 216233 'Socs2' mRNA 5236 5293 5073 148.69 147.59 150.99 117.33 121.05 115.11 149.09 117.83 4378 4564 4322 5200.666667 4421.333333 5.99E-05 -0.245482561 "04630///JAK-STAT signaling pathway+++04910///Insulin signaling pathway+++04917///Prolactin signaling pathway+++04930///Type II diabetes mellitus+++04935///Growth hormone synthesis, secretion and action" GO:0005737///cytoplasm+++GO:0005942///phosphatidylinositol 3-kinase complex GO:0005131///growth hormone receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0008269///JAK pathway signal transduction adaptor activity+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0001558///regulation of cell growth+++GO:0007595///lactation+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0032355///response to estradiol+++GO:0032870///cellular response to hormone stimulus+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0040014///regulation of multicellular organism growth+++GO:0040015///negative regulation of multicellular organism growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0060396///growth hormone receptor signaling pathway+++GO:0060749///mammary gland alveolus development 216238 216238 'Eea1' mRNA 914 910 739 6.1 5.97 5.22 5.96 6.38 6.79 5.763333333 6.376666667 1026 1072 1133 854.3333333 1077 0.001183315 0.326865399 04144///Endocytosis+++04145///Phagosome+++05152///Tuberculosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005969///serine-pyruvate aminotransferase complex+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0044308///axonal spine+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0030742///GTP-dependent protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0006906///vesicle fusion+++GO:0039694///viral RNA genome replication 216274 216274 'Cep290' mRNA 855.21 891.83 840.85 5.17 5.39 5.6 2.86 2.35 2.98 5.386666667 2.73 517.75 425.28 536.69 862.63 493.24 1.34E-13 -0.819716913 GO:0000930///gamma-tubulin complex+++GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0032391///photoreceptor connecting cilium+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0051011///microtubule minus-end binding "GO:0000226///microtubule cytoskeleton organization+++GO:0001822///kidney development+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0030902///hindbrain development+++GO:0030916///otic vesicle formation+++GO:0042462///eye photoreceptor cell development+++GO:0043010///camera-type eye development+++GO:0045494///photoreceptor cell maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048793///pronephros development+++GO:0060041///retina development in camera-type eye+++GO:0060271///cilium assembly+++GO:0070201///regulation of establishment of protein localization+++GO:0090316///positive regulation of intracellular protein transport+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:1905349///ciliary transition zone assembly+++GO:1905515///non-motile cilium assembly" 216285 216285 'Alx1' mRNA 18 9 19 0.4 0.2 0.43 0.43 0.24 0.28 0.343333333 0.316666667 22 12 14 15.33333333 16 0.971641995 0.034986432 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0001843///neural tube closure+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0014031///mesenchymal cell development+++GO:0030326///embryonic limb morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0060021///roof of mouth development" 216292 216292 'Mettl25' mRNA 232 271 196 5.77 6.92 5.28 4.22 3.93 4.71 5.99 4.286666667 189 172 190 233 183.6666667 0.068773933 -0.350557081 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0008150///biological_process+++GO:0032259///methylation 216343 216343 'Tph2' mRNA 1 0 2 0.02 0 0.04 0.02 0.04 0.04 0.02 0.033333333 1 2 2 1 1.666666667 0.80953939 0.700874231 00380///Tryptophan metabolism+++00790///Folate biosynthesis+++04361///Axon regeneration+++04726///Serotonergic synapse GO:0043005///neuron projection "GO:0004497///monooxygenase activity+++GO:0004510///tryptophan 5-monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016714///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen+++GO:0046872///metal ion binding" GO:0006587///serotonin biosynthetic process from tryptophan+++GO:0007623///circadian rhythm+++GO:0009072///aromatic amino acid family metabolic process+++GO:0014823///response to activity+++GO:0031667///response to nutrient levels+++GO:0042427///serotonin biosynthetic process+++GO:0043627///response to estrogen+++GO:0051384///response to glucocorticoid+++GO:0051592///response to calcium ion+++GO:0071285///cellular response to lithium ion 216344 216344 'Rab21' mRNA 168 142 140 5.4 4.41 4.69 6.29 6.72 5.87 4.833333333 6.293333333 229 236 207 150 224 0.003051954 0.567944034 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032154///cleavage furrow+++GO:0032580///Golgi cisterna membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098559///cytoplasmic side of early endosome membrane+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0030516///regulation of axon extension+++GO:0032482///Rab protein signal transduction+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050821///protein stabilization+++GO:2000643///positive regulation of early endosome to late endosome transport 216345 216345 'Zfc3h1' mRNA 967 905 579 7.22 6.65 5.07 5.91 4.94 5.19 6.313333333 5.346666667 836 739 757 817 777.3333333 0.686091078 -0.074989732 GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus GO:0006396///RNA processing+++GO:0008150///biological_process 216350 216350 'Tspan8' mRNA 1545 1478 1484 66.3 63.86 68.93 53.63 53.43 50.36 66.36333333 52.47333333 1392 1339 1270 1502.333333 1333.666667 0.032037225 -0.184405809 GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005178///integrin binding GO:0007283///spermatogenesis+++GO:0010468///regulation of gene expression+++GO:0030195///negative regulation of blood coagulation 216363 216363 'Rab3ip' mRNA 3895 3878 3878 74.99 73.55 79.27 15.75 13.81 13.99 75.93666667 14.51666667 941 805 808 3883.666667 851.3333333 1.23E-189 -2.203569144 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0070319///Golgi to plasma membrane transport vesicle+++GO:1990635///proximal dendrite GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding+++GO:0051020///GTPase binding GO:0006612///protein targeting to membrane+++GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0033365///protein localization to organelle+++GO:0050790///regulation of catalytic activity+++GO:0051490///negative regulation of filopodium assembly+++GO:0060271///cilium assembly 216393 216393 'D930020B18Rik' mRNA 15 21 18 0.22 0.46 0.28 0 0.19 0.06 0.32 0.083333333 0 8 5 18 4.333333333 0.023569837 -2.054312772 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 216395 216395 'Rxylt1' mRNA 603 619 695 20.14 20.05 24.59 22.44 23.14 22.01 21.59333333 22.53 783 777 731 639 763.6666667 0.049648029 0.241714111 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity" GO:0035269///protein O-linked mannosylation 216438 216438 'Marchf9' mRNA 28 56 17 0.8 1.57 0.51 0.64 0.63 0.79 0.96 0.686666667 26 25 31 33.66666667 27.33333333 0.653863948 -0.293914524 GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination 216439 216439 'Agap2' mRNA 3 5 4 0.05 0.07 0.06 0.09 0.13 0.14 0.06 0.12 8 10 12 4 10 0.206459778 1.313404962 04068///FoxO signaling pathway+++04144///Endocytosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0090543///Flemming body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0046872///metal ion binding GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016197///endosomal transport+++GO:0030036///actin cytoskeleton organization+++GO:0032147///activation of protein kinase activity+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0050790///regulation of catalytic activity+++GO:0060749///mammary gland alveolus development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 216440 216440 'Os9' mRNA 4413 4449 4263 59.82 59.16 61.25 61.67 57.85 61.63 60.07666667 60.38333333 5219 4795 5053 4375 5022.333333 0.001493155 0.186794373 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006605///protein targeting+++GO:0006621///protein retention in ER lumen+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034976///response to endoplasmic reticulum stress+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 216441 216441 'Slc26a10' mRNA 37.97 31.6 50.76 0.66 0.58 0.98 1.13 0.8 0.92 0.74 0.95 73.34 49.91 57.64 40.11 60.29666667 0.161157543 0.577118095 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity GO:0008272///sulfate transport+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 216443 216443 'Mars1' mRNA 1462.43 1575 1618.98 26.96 28.62 31.32 23.95 28.01 21.28 28.96666667 24.41333333 1507 1715.51 1300.6 1552.136667 1507.703333 0.707270059 -0.054897858 00450///Selenocompound metabolism+++00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004825///methionine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006431///methionyl-tRNA aminoacylation+++GO:0009267///cellular response to starvation+++GO:0009303///rRNA transcription+++GO:0032869///cellular response to insulin stimulus+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 216445 216445 'Arhgap9' mRNA 34 40 70 1.01 1.16 2.16 19.12 18.19 18.14 1.443333333 18.48333333 738 687 678 48 701 2.96E-86 3.848254256 GO:0005737///cytoplasm "GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding" GO:0007165///signal transduction+++GO:0043087///regulation of GTPase activity 21645 21645 'Tcte1' mRNA 723.82 736.12 685.99 12.91 12.92 12.98 0.61 0.87 0.91 12.93666667 0.796666667 39.15 54.59 56.56 715.31 50.1 5.12E-113 -3.85688675 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0005515///protein binding GO:0030317///flagellated sperm motility 216454 216454 'Rdh16f2' mRNA 1 0 1 0.05 0 0.05 0.08 0.04 0.04 0.033333333 0.053333333 2 1 1 0.666666667 1.333333333 0.763426269 0.965318243 00830///Retinol metabolism GO:0005789///endoplasmic reticulum membrane+++GO:0031301///integral component of organelle membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0016491///oxidoreductase activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:1900054///positive regulation of retinoic acid biosynthetic process 216456 216456 'Gls2' mRNA 41 34 23 0.93 0.76 0.55 0.3 0.14 0.24 0.746666667 0.226666667 15 7 12 32.66666667 11.33333333 0.007919259 -1.534682855 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00470///D-Amino acid metabolism+++04724///Glutamatergic synapse+++04727///GABAergic synapse+++04964///Proximal tubule bicarbonate reclamation+++05206///MicroRNAs in cancer+++05230///Central carbon metabolism in cancer" GO:0005739///mitochondrion GO:0004359///glutaminase activity+++GO:0016787///hydrolase activity GO:0006537///glutamate biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0006543///glutamine catabolic process+++GO:0042981///regulation of apoptotic process+++GO:0072593///reactive oxygen species metabolic process 216459 216459 'Myl6b' mRNA 7 8 5 0.43 0.49 0.33 0.32 0.33 0.28 0.416666667 0.31 6 6 5 6.666666667 5.666666667 0.863090843 -0.239065206 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway GO:0016459///myosin complex+++GO:0016461///unconventional myosin complex GO:0003774///motor activity+++GO:0005509///calcium ion binding+++GO:0008307///structural constituent of muscle GO:0006936///muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0030049///muscle filament sliding 21646 21646 'Tcte2' mRNA 146 162 105 5.86 6.63 4.61 2.72 2.41 1.65 5.7 2.26 75 65 45 137.6666667 61.66666667 3.03E-05 -1.164428677 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21647 21647 'Tcte3' mRNA 331.76 291.32 268 6.57 5.53 5.33 5.28 4.56 4.45 5.81 4.763333333 306.22 270 258.23 297.0266667 278.15 0.594610834 -0.104563344 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0019898///extrinsic component of membrane+++GO:0036126///sperm flagellum GO:0005515///protein binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement 21648 21648 'Dynlt1b' mRNA 408.12 466.18 377.23 36.51 41.36 35.81 83.61 87.04 92.01 37.89333333 87.55333333 1069.45 1083.94 1136.09 417.1766667 1096.493333 3.03E-42 1.385406241 05132///Salmonella infection GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005868///cytoplasmic dynein complex+++GO:0005881///cytoplasmic microtubule+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0044297///cell body+++GO:0099503///secretory vesicle GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030742///GTP-dependent protein binding+++GO:0031681///G-protein beta-subunit binding+++GO:0042802///identical protein binding+++GO:0045505///dynein intermediate chain binding GO:0000132///establishment of mitotic spindle orientation+++GO:0007018///microtubule-based movement+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0016358///dendrite development+++GO:0019060///intracellular transport of viral protein in host cell+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0043087///regulation of GTPase activity+++GO:0048812///neuron projection morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0051301///cell division+++GO:0051493///regulation of cytoskeleton organization+++GO:0060548///negative regulation of cell death+++GO:0061564///axon development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 216505 216505 'Pik3ip1' mRNA 2661 2832 2824 66.75 69.96 75.15 43 46.69 45.75 70.62 45.14666667 1971 2090 2030 2772.333333 2030.333333 1.22E-09 -0.461872683 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0036313///phosphatidylinositol 3-kinase catalytic subunit binding GO:0006508///proteolysis+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity 216516 216516 'Ccdc157' mRNA 1671.25 1861.12 1657.19 19.86 22.01 20.94 8.19 6.85 7.24 20.93666667 7.426666667 778.16 666.22 670.11 1729.853333 704.83 4.30E-51 -1.307504102 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21652 21652 'Phf1' mRNA 1559 1632 1386 35.56 36.65 33.54 17.23 17.25 16.76 35.25 17.08 869 849 818 1525.666667 845.3333333 4.81E-26 -0.861238519 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0035098///ESC/E(Z) complex+++GO:0035861///site of double-strand break" GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0035575///histone demethylase activity (H4-K20 specific)+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:1990226///histone methyltransferase binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031060///regulation of histone methylation+++GO:0033169///histone H3-K9 demethylation+++GO:0035574///histone H4-K20 demethylation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0061087///positive regulation of histone H3-K27 methylation+++GO:0061188///negative regulation of chromatin silencing at rDNA" 216527 216527 'Ccm2' mRNA 428.54 504.23 344.82 12.97 15.11 10.86 15.9 18.24 16.64 12.98 16.92666667 599 667.79 612.16 425.8633333 626.3166667 4.11E-05 0.552977479 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex GO:0005515///protein binding GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001885///endothelial cell development+++GO:0001944///vasculature development+++GO:0007507///heart development+++GO:0035264///multicellular organism growth+++GO:0045216///cell-cell junction organization+++GO:0048839///inner ear development+++GO:0048845///venous blood vessel morphogenesis+++GO:0060039///pericardium development+++GO:0060837///blood vessel endothelial cell differentiation+++GO:0061154///endothelial tube morphogenesis 216543 216543 'Cep68' mRNA 680 673 653 7.57 7.36 7.71 5.86 6.34 5.94 7.546666667 6.046666667 606 641 595 668.6666667 614 0.270996722 -0.134258404 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0034451///centriolar satellite GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding GO:0007098///centrosome cycle+++GO:0010457///centriole-centriole cohesion+++GO:0033365///protein localization to organelle 216549 216549 'Aftph' mRNA 2536 2509 2294 33.98 33.07 32.67 16.95 16.95 15.58 33.24 16.49333333 1439 1405 1282 2446.333333 1375.333333 1.13E-31 -0.841535771 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030121///AP-1 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0030276///clathrin binding GO:0015031///protein transport+++GO:0046907///intracellular transport 216551 216551 'Lgalsl' mRNA 784 812 656 11.84 12.08 10.49 6.06 7.77 7.09 11.47 6.973333333 459 576 518 750.6666667 517.6666667 1.17E-05 -0.542154286 GO:0062023///collagen-containing extracellular matrix GO:0003674///molecular_function+++GO:0030246///carbohydrate binding GO:0008150///biological_process 216558 216558 'Ugp2' mRNA 1816 1901 1563 37.11 38.24 33.97 32.35 29.41 30.13 36.44 30.63 1837 1627 1659 1760 1707.666667 0.596725171 -0.053054332 00040///Pentose and glucuronate interconversions+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm GO:0003983///UTP:glucose-1-phosphate uridylyltransferase activity+++GO:0005536///glucose binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0032557///pyrimidine ribonucleotide binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070569///uridylyltransferase activity GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006011///UDP-glucose metabolic process+++GO:0007420///brain development+++GO:0019255///glucose 1-phosphate metabolic process 216560 216560 'Wdpcp' mRNA 648 736 744 14.56 16.49 17.82 5.19 4.76 5.71 16.29 5.22 270 238 284 709.3333333 264 1.52E-28 -1.440451157 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0097541///axonemal basal plate GO:0005515///protein binding GO:0001822///kidney development+++GO:0002093///auditory receptor cell morphogenesis+++GO:0007224///smoothened signaling pathway+++GO:0007399///nervous system development+++GO:0010762///regulation of fibroblast migration+++GO:0016476///regulation of embryonic cell shape+++GO:0030030///cell projection organization+++GO:0032185///septin cytoskeleton organization+++GO:0032880///regulation of protein localization+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0043587///tongue morphogenesis+++GO:0044782///cilium organization+++GO:0045184///establishment of protein localization+++GO:0048568///embryonic organ development+++GO:0051893///regulation of focal adhesion assembly+++GO:0055123///digestive system development+++GO:0060021///roof of mouth development+++GO:0060271///cilium assembly+++GO:0060541///respiratory system development+++GO:0072359///circulatory system development+++GO:0090521///glomerular visceral epithelial cell migration+++GO:1900027///regulation of ruffle assembly+++GO:2000114///regulation of establishment of cell polarity 216565 216565 'Ehbp1' mRNA 808.64 726.58 573.12 4.06 3.75 2.8 2.35 1.74 2.25 3.536666667 2.113333333 567.99 446.33 523.89 702.78 512.7366667 4.60E-04 -0.464216686 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031941///filamentous actin GO:0005515///protein binding GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0030036///actin cytoskeleton organization 216578 216578 'Papolg' mRNA 392 382 401 4.89 4.54 5.43 4.64 4.03 4.11 4.953333333 4.26 404 342 343 391.6666667 363 0.454918622 -0.124317974 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0043631///RNA polyadenylation 216613 216613 'Ccdc85a' mRNA 720 781 719 4.31 4.65 4.75 1.59 1.39 1.58 4.57 1.52 339 290 332 740 320.3333333 2.97E-26 -1.220161748 GO:0005912///adherens junction+++GO:0030054///cell junction GO:0003674///molecular_function GO:0008150///biological_process 216616 216616 'Efemp1' mRNA 469 496 512 13.1 13.64 15.17 109.05 105.8 109.17 13.97 108.0066667 4478 4240 4341 492.3333333 4353 0 3.131168631 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005006///epidermal growth factor-activated receptor activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0008083///growth factor activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0031346///positive regulation of cell projection organization+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0043010///camera-type eye development+++GO:0048048///embryonic eye morphogenesis+++GO:0048050///post-embryonic eye morphogenesis+++GO:1903975///regulation of glial cell migration" 216618 216618 'Cfap36' mRNA 1488.16 1444.91 1477.44 53.97 52.01 56.17 34.34 35.68 32.31 54.05 34.11 1072.95 1099.16 996.69 1470.17 1056.266667 1.84E-08 -0.490009349 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0005515///protein binding+++GO:0047485///protein N-terminus binding GO:0008150///biological_process 216622 216622 'Fem1al' mRNA 25.98 9 19.04 0.43 0.15 0.34 0.17 0.19 0.16 0.306666667 0.173333333 12.03 13.03 11 18.00666667 12.02 0.472863479 -0.574940005 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0031867///EP4 subtype prostaglandin E2 receptor binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0050728///negative regulation of inflammatory response+++GO:0051438///regulation of ubiquitin-protein transferase activity 216635 216635 'Hbq1a' mRNA 1 1 0 0.13 0.13 0 0 0.23 0 0.086666667 0.076666667 0 2 0 0.666666667 0.666666667 0.998591786 0.039804152 GO:0005833///hemoglobin complex+++GO:0031838///haptoglobin-hemoglobin complex GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0031720///haptoglobin binding+++GO:0043177///organic acid binding+++GO:0046872///metal ion binding GO:0015671///oxygen transport+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification 21664 21664 'Phlda1' mRNA 1342 1402 694 39.23 40.38 21.52 32.65 36.39 30.71 33.71 33.25 1284 1397 1169 1146 1283.333333 0.672964012 0.167396618 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0045210///FasL biosynthetic process 216643 216643 'Gabrp' mRNA 0 0 1 0 0 0.02 0.06 0.08 0.03 0.006666667 0.056666667 4 5 2 0.333333333 3.666666667 0.129250069 3.344669207 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0030594///neurotransmitter receptor activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:1902476///chloride transmembrane transport 21665 21665 'Tdg' mRNA 733.87 691.15 840.96 12.71 11.98 15.52 12.34 13.08 12.69 13.40333333 12.70333333 823.83 835.75 809.97 755.3266667 823.1833333 0.449971199 0.107437508 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016605///PML body GO:0000287///magnesium ion binding+++GO:0000700///mismatch base pair DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0004844///uracil DNA N-glycosylase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008263///pyrimidine-specific mismatch base pair DNA N-glycosylase activity+++GO:0016787///hydrolase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0019904///protein domain specific binding+++GO:0030983///mismatched DNA binding+++GO:0031402///sodium ion binding+++GO:0031404///chloride ion binding+++GO:0032183///SUMO binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0043739///G/U mismatch-specific uracil-DNA glycosylase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006285///base-excision repair, AP site formation+++GO:0006298///mismatch repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032091///negative regulation of protein binding+++GO:0035562///negative regulation of chromatin binding+++GO:0040029///regulation of gene expression, epigenetic+++GO:0045995///regulation of embryonic development+++GO:0080111///DNA demethylation+++GO:1902544///regulation of DNA N-glycosylase activity" 21667 21667 'Tdgf1' mRNA 0 0 4 0 0 0.16 0.03 0 0 0.053333333 0.01 1 0 0 1.333333333 0.333333333 0.619014514 -1.978202577 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0015026///coreceptor activity+++GO:0017147///Wnt-protein binding+++GO:0038100///nodal binding+++GO:0070697///activin receptor binding+++GO:0070698///type I activin receptor binding "GO:0000187///activation of MAPK activity+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001763///morphogenesis of a branching structure+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007369///gastrulation+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0009948///anterior/posterior axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0009966///regulation of signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0038092///nodal signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048856///anatomical structure development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0055007///cardiac muscle cell differentiation+++GO:0071346///cellular response to interferon-gamma+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus" 216705 216705 'Clint1' mRNA 455 510 494 7.27 8.03 8.39 9.85 9.49 10.66 7.896666667 10 706 662 738 486.3333333 702 6.61E-06 0.516755754 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030125///clathrin vesicle coat+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0030276///clathrin binding GO:0006897///endocytosis+++GO:0016192///vesicle-mediated transport+++GO:0048268///clathrin coat assembly 21672 21672 'Prdx2' mRNA 6170 6356 6223 251.88 255.9 269.57 263.93 285.83 276.25 259.1166667 275.3366667 7443 7871 7535 6249.666667 7616.333333 1.01E-05 0.273523816 04214///Apoptosis - fly GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043209///myelin sheath GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0008430///selenium binding+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0051920///peroxiredoxin activity GO:0000187///activation of MAPK activity+++GO:0002357///defense response to tumor cell+++GO:0002536///respiratory burst involved in inflammatory response+++GO:0006979///response to oxidative stress+++GO:0010310///regulation of hydrogen peroxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030194///positive regulation of blood coagulation+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032496///response to lipopolysaccharide+++GO:0033554///cellular response to stress+++GO:0034599///cellular response to oxidative stress+++GO:0042098///T cell proliferation+++GO:0042743///hydrogen peroxide metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0042981///regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045321///leukocyte activation+++GO:0045454///cell redox homeostasis+++GO:0045581///negative regulation of T cell differentiation+++GO:0048538///thymus development+++GO:0048872///homeostasis of number of cells+++GO:0098869///cellular oxidant detoxification+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 216724 216724 'Rufy1' mRNA 937.69 1049.61 748.46 18.46 20.57 15.68 7.83 11.15 9.5 18.23666667 9.493333333 457.02 626.14 540 911.92 541.0533333 2.89E-08 -0.755086992 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0017124///SH3 domain binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0030100///regulation of endocytosis 216725 216725 'Adamts2' mRNA 131.95 112 41 0.96 0.8 0.32 0.49 0.62 0.81 0.693333333 0.64 78.02 95.77 125.02 94.98333333 99.60333333 0.863090843 0.079001234 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0016485///protein processing+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030324///lung development+++GO:0030574///collagen catabolic process+++GO:0043588///skin development 21673 21673 'Dntt' mRNA 0 1 0 0 0.03 0 0.07 0 0.02 0.01 0.03 3 0 1 0.333333333 1.333333333 0.617564164 1.863947205 03450///Non-homologous end-joining+++04640///Hematopoietic cell lineage GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003912///DNA nucleotidylexotransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0034061///DNA polymerase activity+++GO:0046872///metal ion binding GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006304///DNA modification+++GO:0033198///response to ATP+++GO:0071897///DNA biosynthetic process 216739 216739 'Acsl6' mRNA 360 380 323 6.4 6.82 6.42 0.72 1.02 1.1 6.546666667 0.946666667 51 63 63 354.3333333 59 9.30E-42 -2.594507122 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome+++04216///Ferroptosis+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0047676///arachidonate-CoA ligase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007405///neuroblast proliferation+++GO:0008610///lipid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010747///positive regulation of plasma membrane long-chain fatty acid transport+++GO:0010976///positive regulation of neuron projection development+++GO:0015908///fatty acid transport+++GO:0019432///triglyceride biosynthetic process+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process 216742 216742 'Fnip1' mRNA 570 547 516 4.79 4.52 4.61 5.54 4.88 5.14 4.64 5.186666667 766 658 686 544.3333333 703.3333333 0.001217434 0.357659578 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042030///ATPase inhibitor activity+++GO:0051087///chaperone binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002327///immature B cell differentiation+++GO:0002904///positive regulation of B cell apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0009267///cellular response to starvation+++GO:0031334///positive regulation of protein complex assembly+++GO:0031929///TOR signaling+++GO:0032007///negative regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2000973///regulation of pro-B cell differentiation 21676 21676 'Tead1' mRNA 767 723 709 4.08 3.78 4.01 4.55 4.09 4.59 3.956666667 4.41 984 867 962 733 937.6666667 5.33E-04 0.342910787 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003143///embryonic heart tube morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0014883///transition between fast and slow fiber+++GO:0030903///notochord development+++GO:0035329///hippo signaling+++GO:0042127///regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048339///paraxial mesoderm development+++GO:0048368///lateral mesoderm development+++GO:0048568///embryonic organ development+++GO:0065003///protein-containing complex assembly+++GO:0071300///cellular response to retinoic acid+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1902459///positive regulation of stem cell population maintenance+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 216760 216760 'Mfap3' mRNA 714 605 686 7.92 6.6 8.05 10.22 9.89 10.58 7.523333333 10.23 1063 1005 1065 668.3333333 1044.333333 1.66E-09 0.629892759 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 216766 216766 'Gemin5' mRNA 745 851 761 6.37 7.16 6.89 4.11 3.97 3.95 6.806666667 4.01 553 523 515 785.6666667 530.3333333 4.51E-08 -0.578462447 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0034718///SMN-Gemin2 complex+++GO:0034719///SMN-Sm protein complex+++GO:0097504///Gemini of coiled bodies GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0017069///snRNA binding+++GO:0030619///U1 snRNA binding+++GO:0030621///U4 snRNA binding+++GO:0030622///U4atac snRNA binding+++GO:0043022///ribosome binding GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0008380///RNA splicing 216767 216767 'Mrpl22' mRNA 419 381 394 39.59 36.16 39.73 43.15 57.33 50.1 38.49333333 50.19333333 522 673 580 398 591.6666667 5.18E-05 0.561957168 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0042255///ribosome assembly 21677 21677 'Tead2' mRNA 678 703 440 19.91 20.28 13.77 16.02 16.23 15.33 17.98666667 15.86 624 619 578 607 607 0.995898276 -0.002693578 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001570///vasculogenesis+++GO:0001843///neural tube closure+++GO:0003143///embryonic heart tube morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030903///notochord development+++GO:0035329///hippo signaling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048339///paraxial mesoderm development+++GO:0048368///lateral mesoderm development+++GO:0048568///embryonic organ development+++GO:0060548///negative regulation of cell death+++GO:0065003///protein-containing complex assembly+++GO:0071300///cellular response to retinoic acid+++GO:2000736///regulation of stem cell differentiation" 21678 21678 'Tead3' mRNA 238 248 133 5.35 5.36 3.14 3.62 4.32 3.8 4.616666667 3.913333333 191 220 192 206.3333333 201 0.896925082 -0.036650209 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035329///hippo signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0055059///asymmetric neuroblast division+++GO:1902459///positive regulation of stem cell population maintenance" 216783 216783 'Olfr320' mRNA 1 0 0 0.07 0 0 0 0 0.06 0.023333333 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 21679 21679 'Tead4' mRNA 138 144 121 2.5 2.58 2.32 1.69 1.27 1.6 2.466666667 1.52 108 80 99 134.3333333 95.66666667 0.043512558 -0.500790979 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0032993///protein-DNA complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001825///blastocyst formation+++GO:0001830///trophectodermal cell fate commitment+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007566///embryo implantation+++GO:0035329///hippo signaling+++GO:0045165///cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:1902459///positive regulation of stem cell population maintenance" 216792 216792 'Iba57' mRNA 91 82 66 1.22 1.08 0.96 1.09 1.14 1.33 1.086666667 1.186666667 94 96 111 79.66666667 100.3333333 0.280037651 0.325870618 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0016740///transferase activity GO:0006783///heme biosynthetic process+++GO:0016226///iron-sulfur cluster assembly 216795 216795 'Wnt9a' mRNA 317 379 311 5.17 6.11 5.36 3 2.66 3.69 5.546666667 3.116666667 210 182 251 335.6666667 214.3333333 1.20E-04 -0.657039868 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045165///cell fate commitment+++GO:0045597///positive regulation of cell differentiation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048856///anatomical structure development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060548///negative regulation of cell death+++GO:0061037///negative regulation of cartilage development 216797 216797 'Prss38' mRNA 4 4 5 0.2 0.19 0.22 0.04 0.07 0.04 0.203333333 0.05 1 3 1 4.333333333 1.666666667 0.405930009 -1.389477278 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 216799 216799 'Nlrp3' mRNA 18 9 7 0.25 0.12 0.11 1.21 0.7 0.88 0.16 0.93 102 58 71 11.33333333 77 1.41E-09 2.753638016 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05164///Influenza A+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0061702///inflammasome complex+++GO:0072559///NLRP3 inflammasome complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding GO:0002376///immune system process+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002526///acute inflammatory response+++GO:0002674///negative regulation of acute inflammatory response+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002830///positive regulation of type 2 immune response+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0014070///response to organic cyclic compound+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032611///interleukin-1 beta production+++GO:0032612///interleukin-1 production+++GO:0032621///interleukin-18 production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044546///NLRP3 inflammasome complex assembly+++GO:0045087///innate immune response+++GO:0045471///response to ethanol+++GO:0045630///positive regulation of T-helper 2 cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071224///cellular response to peptidoglycan+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:2000321///positive regulation of T-helper 17 cell differentiation+++GO:2000553///positive regulation of T-helper 2 cell cytokine production 216805 216805 'Flcn' mRNA 2553.3 2531.09 2492.01 43.87 43.08 45.57 35.81 35.61 34.65 44.17333333 35.35666667 2396.09 2324.54 2243 2525.466667 2321.21 0.066943108 -0.134108952 04150///mTOR signaling pathway+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0044291///cell-cell contact zone+++GO:0072686///mitotic spindle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007043///cell-cell junction assembly+++GO:0008285///negative regulation of cell proliferation+++GO:0009267///cellular response to starvation+++GO:0010508///positive regulation of autophagy+++GO:0010629///negative regulation of gene expression+++GO:0010823///negative regulation of mitochondrion organization+++GO:0016525///negative regulation of angiogenesis+++GO:0030097///hemopoiesis+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031929///TOR signaling+++GO:0032006///regulation of TOR signaling+++GO:0032007///negative regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0032418///lysosome localization+++GO:0032465///regulation of cytokinesis+++GO:0034198///cellular response to amino acid starvation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035065///regulation of histone acetylation+++GO:0043547///positive regulation of GTPase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046578///regulation of Ras protein signal transduction+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0097009///energy homeostasis+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1901723///negative regulation of cell proliferation involved in kidney development+++GO:1901856///negative regulation of cellular respiration+++GO:1901859///negative regulation of mitochondrial DNA metabolic process+++GO:1901862///negative regulation of muscle tissue development+++GO:1901874///negative regulation of post-translational protein modification+++GO:1903444///negative regulation of brown fat cell differentiation+++GO:1904263///positive regulation of TORC1 signaling+++GO:2000973///regulation of pro-B cell differentiation+++GO:2001170///negative regulation of ATP biosynthetic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 21681 21681 'Alyref' mRNA 76 84 57 4.17 4.56 3.32 6.75 6.92 6.29 4.016666667 6.653333333 141 141 127 72.33333333 136.3333333 3.07E-04 0.90832925 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome+++05014///Amyotrophic lateral sclerosis+++05168///Herpes simplex virus 1 infection "GO:0000346///transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0071013///catalytic step 2 spliceosome" GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000018///regulation of DNA recombination+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport" 216810 216810 'Tom1l2' mRNA 5393.75 5806.66 5774.78 69.47 73.7 78.27 38.33 36.53 34.61 73.81333333 36.49 3449.04 3167.52 3002.92 5658.396667 3206.493333 4.49E-33 -0.83362435 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0032810///sterol response element binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003062///regulation of heart rate by chemical signal+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0007623///circadian rhythm+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0008610///lipid biosynthetic process+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010876///lipid localization+++GO:0010883///regulation of lipid storage+++GO:0014070///response to organic cyclic compound+++GO:0015031///protein transport+++GO:0019217///regulation of fatty acid metabolic process+++GO:0030324///lung development+++GO:0030522///intracellular receptor signaling pathway+++GO:0031065///positive regulation of histone deacetylation+++GO:0031647///regulation of protein stability+++GO:0032094///response to food+++GO:0032526///response to retinoic acid+++GO:0032570///response to progesterone+++GO:0032869///cellular response to insulin stimulus+++GO:0032933///SREBP signaling pathway+++GO:0033762///response to glucagon+++GO:0033993///response to lipid+++GO:0042493///response to drug+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043434///response to peptide hormone+++GO:0045089///positive regulation of innate immune response+++GO:0045444///fat cell differentiation+++GO:0045471///response to ethanol+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0050796///regulation of insulin secretion+++GO:0051591///response to cAMP+++GO:0070542///response to fatty acid+++GO:0071398///cellular response to fatty acid+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903214///regulation of protein targeting to mitochondrion" 21682 21682 'Tec' mRNA 533 529 737 11.24 10.98 16.37 26.92 22.64 24.95 12.86333333 24.83666667 1472 1187 1322 599.6666667 1327 3.54E-16 1.123221053 04013///MAPK signaling pathway - fly+++04380///Osteoclast differentiation+++04660///T cell receptor signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007229///integrin-mediated signaling pathway+++GO:0010543///regulation of platelet activation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042246///tissue regeneration+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway 216820 216820 'Dhrs7b' mRNA 792.94 826.41 796.08 28.46 29.71 30.34 33.14 35.87 35.64 29.50333333 34.88333333 1039.87 1081.28 1096.13 805.1433333 1072.426667 1.67E-05 0.402450323 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000140///acylglycerone-phosphate reductase activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006954///inflammatory response+++GO:0008611///ether lipid biosynthetic process+++GO:0010468///regulation of gene expression+++GO:0030223///neutrophil differentiation+++GO:0032091///negative regulation of protein binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050873///brown fat cell differentiation+++GO:0060612///adipose tissue development+++GO:0120161///regulation of cold-induced thermogenesis" 216821 216821 'Tmem11' mRNA 674 648 643 32.91 31.61 33.26 34.18 37.59 32.92 32.59333333 34.89666667 801 869 766 655 812 0.00633122 0.298715115 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0003674///molecular_function GO:0007005///mitochondrion organization+++GO:0007007///inner mitochondrial membrane organization 216825 216825 'Usp22' mRNA 2919 3172 3502 35.29 37.71 44.91 32.42 28.98 32.59 39.30333333 31.33 3087 2696 3006 3197.666667 2929.666667 0.155926743 -0.14345648 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0070461///SAGA-type complex GO:0003713///transcription coactivator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0016574///histone ubiquitination+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle" 216829 216829 'Mmgt2' mRNA 834 833 844 29.17 28.63 31.06 23.48 21.43 23.79 29.62 22.9 797 696 767 837 753.3333333 0.13419885 -0.165611528 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031901///early endosome membrane+++GO:0072546///ER membrane protein complex GO:0005375///copper ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0015087///cobalt ion transmembrane transporter activity+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0015099///nickel cation transmembrane transporter activity+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0032977///membrane insertase activity GO:0006812///cation transport+++GO:0006824///cobalt ion transport+++GO:0006825///copper ion transport+++GO:0006828///manganese ion transport+++GO:0015675///nickel cation transport+++GO:0015693///magnesium ion transport+++GO:0035434///copper ion transmembrane transport+++GO:0035444///nickel cation transmembrane transport+++GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071421///manganese ion transmembrane transport+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1903830///magnesium ion transmembrane transport 21683 21683 'Tecta' mRNA 14823 14921 14151 106.64 105.39 107.87 33.77 34.39 33.03 106.6333333 33.73 5429 5399 5143 14631.66667 5323.666667 1.61E-187 -1.470094546 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding GO:0007160///cell-matrix adhesion+++GO:0007605///sensory perception of sound 216831 216831 'Arhgap44' mRNA 613 691 719 8.94 10.01 11.19 3.81 4.38 3.92 10.04666667 4.036666667 307 334 300 674.3333333 313.6666667 7.90E-18 -1.118152814 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031256///leading edge membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0055037///recycling endosome+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity+++GO:0005543///phospholipid binding+++GO:0031267///small GTPase binding "GO:0007165///signal transduction+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035020///regulation of Rac protein signal transduction+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0051490///negative regulation of filopodium assembly+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0098886///modification of dendritic spine+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099010///modification of postsynaptic structure+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane" 216835 216835 'Usp43' mRNA 73 91 62 0.97 1.28 0.91 0.46 0.46 0.43 1.053333333 0.45 36 34 33 75.33333333 34.33333333 9.40E-04 -1.140053667 GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 21684 21684 'Tectb' mRNA 8649 8862 8944 175.27 177.8 190.79 17.98 16.86 17.49 181.2866667 17.44333333 1039 937 976 8818.333333 984 0 -3.177755369 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding GO:0007605///sensory perception of sound 216846 216846 'Cntrob' mRNA 417 417 428 5.48 5.41 6.05 3.82 3.92 3.73 5.646666667 3.823333333 330 334 312 420.6666667 325.3333333 0.00579094 -0.383657452 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0019904///protein domain specific binding GO:0007049///cell cycle+++GO:0007099///centriole replication+++GO:0051299///centrosome separation+++GO:0051301///cell division+++GO:1902017///regulation of cilium assembly+++GO:1902410///mitotic cytokinetic process 216848 216848 'Chd3' mRNA 1035 1037 839 7.45 7.36 6.44 7.71 7.49 6.84 7.083333333 7.346666667 1229 1169 1060 970.3333333 1152.666667 0.017161902 0.239960973 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0016581///NuRD complex+++GO:0016605///PML body+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0036121///double-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0046872///metal ion binding+++GO:0070615///nucleosome-dependent ATPase activity+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003226///right ventricular compact myocardium morphogenesis+++GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing+++GO:0007051///spindle organization+++GO:0007098///centrosome cycle+++GO:0007417///central nervous system development+++GO:0007512///adult heart development+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008015///blood circulation+++GO:0009617///response to bacterium+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0021545///cranial nerve development+++GO:0021553///olfactory nerve development+++GO:0021772///olfactory bulb development+++GO:0030217///T cell differentiation+++GO:0030540///female genitalia development+++GO:0032508///DNA duplex unwinding+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035904///aorta development+++GO:0035909///aorta morphogenesis+++GO:0036302///atrioventricular canal development+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042048///olfactory behavior+++GO:0042471///ear morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0043010///camera-type eye development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043584///nose development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048752///semicircular canal morphogenesis+++GO:0048771///tissue remodeling+++GO:0048806///genitalia development+++GO:0048844///artery morphogenesis+++GO:0050767///regulation of neurogenesis+++GO:0050890///cognition+++GO:0060021///roof of mouth development+++GO:0060041///retina development in camera-type eye+++GO:0060123///regulation of growth hormone secretion+++GO:0060173///limb development+++GO:0060324///face development+++GO:0060384///innervation+++GO:0060411///cardiac septum morphogenesis+++GO:0060429///epithelium development+++GO:0062009///secondary palate development 21685 21685 'Tef' mRNA 3261 3556 2922 39.71 42.83 38.12 17.22 17.87 18.83 40.22 17.97333333 1603 1628 1696 3246.333333 1642.333333 7.02E-45 -0.991364611 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process" 216850 216850 'Kdm6b' mRNA 2035 1933 2060 15.75 14.7 16.9 9.58 9.13 10.32 15.78333333 9.676666667 1425 1327 1487 2009.333333 1413 3.97E-10 -0.521972406 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044666///MLL3/4 complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0071558///histone demethylase activity (H3-K27 specific) GO:0002437///inflammatory response to antigenic stimulus+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006954///inflammatory response+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0014823///response to activity+++GO:0016577///histone demethylation+++GO:0021766///hippocampus development+++GO:0045165///cell fate commitment+++GO:0045446///endothelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048333///mesodermal cell differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:0060992///response to fungicide+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071557///histone H3-K27 demethylation+++GO:0120162///positive regulation of cold-induced thermogenesis 216853 216853 'Wrap53' mRNA 314 342 327 9.77 10.5 10.76 9.29 8.64 8.32 10.34333333 8.75 344 311 296 327.6666667 317 0.753790448 -0.060707908 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0035861///site of double-strand break" GO:0003723///RNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding+++GO:0070034///telomerase RNA binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007004///telomere maintenance via telomerase+++GO:0030576///Cajal body organization+++GO:0032203///telomere formation via telomerase+++GO:0034337///RNA folding+++GO:0045739///positive regulation of DNA repair+++GO:0051973///positive regulation of telomerase activity+++GO:0090666///scaRNA localization to Cajal body+++GO:0090671///telomerase RNA localization to Cajal body+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:1904867///protein localization to Cajal body+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2000781///positive regulation of double-strand break repair+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 216856 216856 'Nlgn2' mRNA 524 519 449 5.44 5.36 5.02 5.22 4.89 5.16 5.273333333 5.09 567 524 545 497.3333333 545.3333333 0.356384365 0.123065859 04514///Cell adhesion molecules GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0060077///inhibitory synapse+++GO:0097470///ribbon synapse+++GO:0098690///glycinergic synapse+++GO:0098691///dopaminergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042043///neurexin family protein binding+++GO:0042802///identical protein binding+++GO:0050839///cell adhesion molecule binding "GO:0001966///thigmotaxis+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0007155///cell adhesion+++GO:0007158///neuron cell-cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007416///synapse assembly+++GO:0007630///jump response+++GO:0008284///positive regulation of cell proliferation+++GO:0019233///sensory perception of pain+++GO:0032024///positive regulation of insulin secretion+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0034394///protein localization to cell surface+++GO:0035176///social behavior+++GO:0035418///protein localization to synapse+++GO:0035641///locomotory exploration behavior+++GO:0048488///synaptic vesicle endocytosis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0050885///neuromuscular process controlling balance+++GO:0051932///synaptic transmission, GABAergic+++GO:0051965///positive regulation of synapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060999///positive regulation of dendritic spine development+++GO:0072553///terminal button organization+++GO:0072578///neurotransmitter-gated ion channel clustering+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0098698///postsynaptic specialization assembly+++GO:1901142///insulin metabolic process+++GO:1902474///positive regulation of protein localization to synapse+++GO:1904034///positive regulation of t-SNARE clustering+++GO:1904862///inhibitory synapse assembly+++GO:1905606///regulation of presynapse assembly+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000809///positive regulation of synaptic vesicle clustering" 216858 216858 'Kctd11' mRNA 416 387 356 8.46 7.74 7.68 9.89 9.25 9.96 7.96 9.7 560 511 546 386.3333333 539 1.21E-04 0.469737836 GO:0005737///cytoplasm GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0040008///regulation of growth+++GO:0042127///regulation of cell proliferation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0051260///protein homooligomerization 216859 216859 'Acap1' mRNA 14 6 16 0.31 0.13 0.38 1.29 1.42 1.27 0.273333333 1.326666667 66 71 62 12 66.33333333 6.37E-08 2.447389551 04144///Endocytosis GO:0005768///endosome+++GO:0016020///membrane+++GO:0055038///recycling endosome membrane GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0016042///lipid catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 216860 216860 'Neurl4' mRNA 580 551 575 8.36 7.74 8.65 5.78 6.36 5.86 8.25 6 466 488 448 568.6666667 467.3333333 0.017935472 -0.295728713 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 216864 216864 'Mgl2' mRNA 62.77 80.79 53.34 2.51 3.24 2.31 5.74 6.21 6.3 2.686666667 6.083333333 172.34 172.45 173.11 65.63333333 172.6333333 2.77E-09 1.400191396 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0044419///interspecies interaction between organisms 216867 216867 'Slc16a11' mRNA 1174 1359 1012 43.91 49.83 40.44 32.83 40.01 36.54 44.72666667 36.46 1005 1179 1072 1181.666667 1085.333333 0.29700558 -0.128059224 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0050833///pyruvate transmembrane transporter activity GO:0006629///lipid metabolic process+++GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport+++GO:1901475///pyruvate transmembrane transport 216869 216869 'Arrb2' mRNA 231 313 143 6.72 9.55 4.41 25.51 28.28 25.47 6.893333333 26.42 979 1060 962 229 1000.333333 6.83E-37 2.128739789 "04010///MAPK signaling pathway+++04062///Chemokine signaling pathway+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++05032///Morphine addiction+++05207///Chemical carcinogenesis - receptor activation" GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0001664///G protein-coupled receptor binding+++GO:0002046///opsin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031691///alpha-1A adrenergic receptor binding+++GO:0031692///alpha-1B adrenergic receptor binding+++GO:0031701///angiotensin receptor binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0031748///D1 dopamine receptor binding+++GO:0031762///follicle-stimulating hormone receptor binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0031859///platelet activating factor receptor binding+++GO:0042802///identical protein binding+++GO:0043422///protein kinase B binding+++GO:0044877///protein-containing complex binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0051219///phosphoprotein binding+++GO:0071889///14-3-3 protein binding+++GO:1990763///arrestin family protein binding "GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002031///G protein-coupled receptor internalization+++GO:0002032///desensitization of G protein-coupled receptor signaling pathway by arrestin+++GO:0002092///positive regulation of receptor internalization+++GO:0006366///transcription by RNA polymerase II+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0007601///visual perception+++GO:0007628///adult walking behavior+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031623///receptor internalization+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032226///positive regulation of synaptic transmission, dopaminergic+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050896///response to stimulus+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051928///positive regulation of calcium ion transport+++GO:0060326///cell chemotaxis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:1904037///positive regulation of epithelial cell apoptotic process+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000727///positive regulation of cardiac muscle cell differentiation" 21687 21687 'Tek' mRNA 360 371 398 4.09 4.15 4.81 4.38 4.63 4 4.35 4.336666667 443 458 392 376.3333333 431 0.249161698 0.181636112 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++05323///Rheumatoid arthritis GO:0001725///stress fiber+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0034451///centriolar satellite+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0001936///regulation of endothelial cell proliferation+++GO:0001958///endochondral ossification+++GO:0002040///sprouting angiogenesis+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0006468///protein phosphorylation+++GO:0007160///cell-matrix adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0010033///response to organic substance+++GO:0010595///positive regulation of endothelial cell migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030097///hemopoiesis+++GO:0030334///regulation of cell migration+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0032526///response to retinoic acid+++GO:0032878///regulation of establishment or maintenance of cell polarity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043434///response to peptide hormone+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0043627///response to estrogen+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0045785///positive regulation of cell adhesion+++GO:0046777///protein autophosphorylation+++GO:0048014///Tie signaling pathway+++GO:0051591///response to cAMP+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060347///heart trabecula formation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072012///glomerulus vasculature development+++GO:0098609///cell-cell adhesion+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1902533///positive regulation of intracellular signal transduction+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2000352///negative regulation of endothelial cell apoptotic process 216871 216871 'Gltpd2' mRNA 7 6 11 0.36 0.3 0.6 0.22 0.32 0.23 0.42 0.256666667 5 7 5 8 5.666666667 0.665933987 -0.519512665 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0120013///intermembrane lipid transfer activity+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0035627///ceramide transport+++GO:0120009///intermembrane lipid transfer+++GO:1902389///ceramide 1-phosphate transport 216873 216873 'Spag7' mRNA 2121 2335 2136 113.38 123.01 121.29 119.95 124.74 117.04 119.2266667 120.5766667 2583 2615 2436 2197.333333 2544.666667 0.007075397 0.200560967 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0008150///biological_process 216874 216874 'Camta2' mRNA 1586 1559 1372 18.13 17.67 16.79 12.74 14.07 12.11 17.53 12.97333333 1270 1371 1178 1505.666667 1273 0.005860341 -0.251071274 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0045944///positive regulation of transcription by RNA polymerase II 216877 216877 'Dhx33' mRNA 516 522 612 5.32 5.29 6.69 4.05 3.81 3.55 5.766666667 3.803333333 450 416 384 550 416.6666667 0.003146819 -0.417749472 04621///NOD-like receptor signaling pathway GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0061702///inflammasome complex+++GO:0072559///NLRP3 inflammasome complex GO:0000166///nucleotide binding+++GO:0000182///rDNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0033613///activating transcription factor binding+++GO:0043023///ribosomal large subunit binding GO:0006413///translational initiation+++GO:0032481///positive regulation of type I interferon production+++GO:0043410///positive regulation of MAPK cascade+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly 216881 216881 'Wscd1' mRNA 530 584 509 10.71 11.57 10.98 11.59 10.32 10.7 11.08666667 10.87 677 580 595 541 617.3333333 0.150640403 0.178928861 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0008146///sulfotransferase activity GO:0008150///biological_process 21689 21689 'Tekt1' mRNA 2151 2162 2098 92.17 91.52 95.13 10.47 12.07 11.63 92.94 11.39 275 315 301 2137 297 5.46E-207 -2.858217768 GO:0005874///microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility 216892 216892 'Spns2' mRNA 174 143 130.12 3.2 2.55 2.58 1.69 2.08 2.08 2.776666667 1.95 110 128 125 149.04 121 0.215216125 -0.307880363 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity+++GO:0046624///sphingolipid transporter activity GO:0001782///B cell homeostasis+++GO:0002260///lymphocyte homeostasis+++GO:0002920///regulation of humoral immune response+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006665///sphingolipid metabolic process+++GO:0006869///lipid transport+++GO:0043029///T cell homeostasis+++GO:0048073///regulation of eye pigmentation+++GO:0048535///lymph node development+++GO:0055085///transmembrane transport+++GO:0060348///bone development+++GO:0072676///lymphocyte migration 216961 216961 'Coro6' mRNA 89 84 75 2.02 1.84 1.8 4.35 3.53 4.23 1.886666667 4.036666667 220 172 204 82.66666667 198.6666667 5.01E-09 1.253398928 GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0016477///cell migration 216963 216963 'Git1' mRNA 751 828 775 10.97 11.91 11.93 12.04 11.84 11.15 11.60333333 11.67666667 946 915 854 784.6666667 905 0.06503732 0.193766374 04144///Endocytosis+++04810///Regulation of actin cytoskeleton+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0097431///mitotic spindle pole+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0098879///structural constituent of postsynaptic specialization GO:0001771///immunological synapse formation+++GO:0001957///intramembranous ossification+++GO:0007420///brain development+++GO:0007626///locomotory behavior+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032013///negative regulation of ARF protein signal transduction+++GO:0032465///regulation of cytokinesis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0045454///cell redox homeostasis+++GO:0045820///negative regulation of glycolytic process+++GO:0048013///ephrin receptor signaling pathway+++GO:0048666///neuron development+++GO:0050790///regulation of catalytic activity+++GO:0060996///dendritic spine development+++GO:0061743///motor learning+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0090063///positive regulation of microtubule nucleation+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0106015///negative regulation of inflammatory response to wounding+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000646///positive regulation of receptor catabolic process 216964 216964 'Trp53i13' mRNA 1043 998 948 44.56 41.69 42.98 33.89 35.09 33.07 43.07666667 34.01666667 920 924 862 996.3333333 902 0.121006833 -0.154458535 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009411///response to UV+++GO:0014070///response to organic cyclic compound+++GO:0042493///response to drug+++GO:0045786///negative regulation of cell cycle 216965 216965 'Taok1' mRNA 1704 1656 1672 7.4 7.08 7.74 8.18 7.04 7.33 7.406666667 7.516666667 2155 1819 1894 1677.333333 1956 0.014294768 0.207690529 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0031489///myosin V binding+++GO:0043014///alpha-tubulin binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0048487///beta-tubulin binding GO:0000165///MAPK cascade+++GO:0000226///microtubule cytoskeleton organization+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048812///neuron projection morphogenesis+++GO:0051493///regulation of cytoskeleton organization+++GO:0070050///neuron cellular homeostasis+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0097194///execution phase of apoptosis+++GO:1901985///positive regulation of protein acetylation 216971 216971 'Fam222b' mRNA 1410 1464 1401 19.76 20.18 20.84 12.57 11.29 11.57 20.26 11.81 1027 900 918 1425 948.3333333 1.11E-12 -0.600401288 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 216974 216974 'Proca1' mRNA 73.4 60.42 87.05 2.87 2.32 3.57 2.8 2.6 2.29 2.92 2.563333333 81.2 81.99 68.65 73.62333333 77.28 0.907497403 0.045266245 GO:0005575///cellular_component+++GO:0005739///mitochondrion GO:0004623///phospholipase A2 activity+++GO:0030332///cyclin binding "GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0006644///phospholipid metabolic process+++GO:0007005///mitochondrion organization+++GO:0008150///biological_process+++GO:0035694///mitochondrial protein catabolic process+++GO:0050482///arachidonic acid secretion" 216976 216976 'Rskr' mRNA 2 8 9 0.04 0.14 0.17 0.13 0.1 0.17 0.116666667 0.133333333 8 6 10 6.333333333 8 0.812151505 0.313629145 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 216984 216984 'Evi2b' mRNA 32.35 87 50.86 0.5 1.32 0.83 5.28 3.54 3.95 0.883333333 4.256666667 394.83 258.64 285.96 56.73666667 313.1433333 7.78E-20 2.460222541 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0030854///positive regulation of granulocyte differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045660///positive regulation of neutrophil differentiation+++GO:0051726///regulation of cell cycle+++GO:0061515///myeloid cell development+++GO:0071157///negative regulation of cell cycle arrest+++GO:2000035///regulation of stem cell division 216987 216987 'Utp6' mRNA 1142 1138 883 15.95 15.64 13.08 14.9 13.13 14.89 14.89 14.30666667 1228 1057 1188 1054.333333 1157.666667 0.261491881 0.12692741 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome GO:0030515///snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0006396///RNA processing" 216991 216991 'Adap2' mRNA 362.26 324.49 326.23 7.92 6.71 7.51 28.11 24.84 23.95 7.38 25.63333333 1517.23 1317.78 1332.49 337.66 1389.166667 2.07E-90 2.028734347 GO:0005737///cytoplasm+++GO:0005740///mitochondrial envelope+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005096///GTPase activator activity+++GO:0005545///1-phosphatidylinositol binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0043533///inositol 1,3,4,5 tetrakisphosphate binding+++GO:0046872///metal ion binding+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0007507///heart development+++GO:0043547///positive regulation of GTPase activity+++GO:0048017///inositol lipid-mediated signaling+++GO:0050790///regulation of catalytic activity 217011 217011 'Nle1' mRNA 175 181 111 5.64 5.76 3.83 4.72 4.61 4.42 5.076666667 4.583333333 167 160 152 155.6666667 159.6666667 0.906701399 0.033198475 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0000027///ribosomal large subunit assembly+++GO:0001756///somitogenesis+++GO:0001822///kidney development+++GO:0001826///inner cell mass cell differentiation+++GO:0007219///Notch signaling pathway+++GO:0042273///ribosomal large subunit biogenesis+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0048705///skeletal system morphogenesis+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 217012 217012 'Unc45b' mRNA 36 32 47 0.55 0.48 0.76 0.78 0.8 0.96 0.596666667 0.846666667 59 59 70 38.33333333 62.66666667 0.07192958 0.690632374 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0051879///Hsp90 protein binding GO:0002088///lens development in camera-type eye+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0030154///cell differentiation+++GO:0061077///chaperone-mediated protein folding 217026 217026 'Heatr6' mRNA 730.87 683 728.14 6.73 6.22 7.13 5.73 5.06 6.23 6.693333333 5.673333333 715.78 614 754 714.0033333 694.5933333 0.731121666 -0.053845769 GO:0005575///cellular_component GO:0008150///biological_process 217030 217030 'Synrg' mRNA 513.47 516.29 537.08 3.75 3.74 4.18 4.76 3.63 4.26 3.89 4.216666667 715.81 543.2 608.25 522.28 622.42 0.079871807 0.237147302 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0006897///endocytosis+++GO:0008150///biological_process+++GO:0015031///protein transport 217031 217031 'Tada2a' mRNA 602 576 671 17.46 16.5 20.43 12.7 11.32 11.85 18.13 11.95666667 506 446 470 616.3333333 474 0.002393296 -0.395472222 GO:0000124///SAGA complex+++GO:0000125///PCAF complex+++GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005694///chromosome+++GO:0070461///SAGA-type complex+++GO:0072686///mitotic spindle GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity "GO:0000278///mitotic cell cycle+++GO:0001932///regulation of protein phosphorylation+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031063///regulation of histone deacetylation+++GO:0031647///regulation of protein stability+++GO:0035065///regulation of histone acetylation+++GO:0035066///positive regulation of histone acetylation+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation" 217038 217038 'Mrm1' mRNA 188 202 166 4.23 4.48 3.96 6.65 7.12 6.93 4.223333333 6.9 340 355 343 185.3333333 346 7.52E-09 0.892045328 GO:0005739///mitochondrion GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0070039///rRNA (guanosine-2'-O-)-methyltransferase activity GO:0000451///rRNA 2'-O-methylation+++GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0032259///methylation 217039 217039 'Ggnbp2' mRNA 2014 1995 1447 36.72 36.02 28.25 29.5 36.13 34.02 33.66333333 33.21666667 1832 2220 2065 1818.666667 2039 0.17603531 0.16204059 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0033140///negative regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0060711///labyrinthine layer development+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061099///negative regulation of protein tyrosine kinase activity 217057 217057 'Ptrh2' mRNA 447 503 478 8.31 9.21 9.45 8.45 8.41 8.53 8.99 8.463333333 522 507 511 476 513.3333333 0.511411657 0.096628292 GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004045///aminoacyl-tRNA hydrolase activity+++GO:0016787///hydrolase activity GO:0010629///negative regulation of gene expression+++GO:2000210///positive regulation of anoikis+++GO:2000811///negative regulation of anoikis 217066 217066 'Elobl' mRNA 7 7 8 0.71 0.7 0.86 0.98 1.09 1.74 0.756666667 1.27 12 15 20 7.333333333 15.66666667 0.178260831 1.083248487 GO:0030891///VCB complex+++GO:0070449///elongin complex GO:0006368///transcription elongation from RNA polymerase II promoter 217069 217069 'Trim25' mRNA 920 918 801 8.82 8.73 8.19 14.57 12.22 14.14 8.58 13.64333333 1751 1437 1641 879.6666667 1609.666667 1.58E-22 0.860687308 04064///NF-kappa B signaling pathway+++04622///RIG-I-like receptor signaling pathway+++05164///Influenza A GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016604///nuclear body GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0039552///RIG-I binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032880///regulation of protein localization+++GO:0033280///response to vitamin D+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043627///response to estrogen+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:1902186///regulation of viral release from host cell+++GO:1902187///negative regulation of viral release from host cell+++GO:1990830///cellular response to leukemia inhibitory factor" 217071 217071 'Gm525' mRNA 1752 1730 1724 260.2 257.35 273.25 141.19 159.11 148.61 263.6 149.6366667 1104 1185 1113 1735.333333 1134 1.87E-14 -0.625527305 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 217082 217082 'Hlf' mRNA 1130 1114 973 11.64 11.37 10.67 10.84 10.21 11.1 11.22666667 10.71666667 1200 1107 1203 1072.333333 1170 0.233458825 0.115873496 04711///Circadian rhythm - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035914///skeletal muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process" 217109 217109 'Utp18' mRNA 360 370 134 7.65 7.74 3.02 4.91 8.77 6.98 6.136666667 6.886666667 266 464 366 288 365.3333333 0.567981277 0.357673446 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031965///nuclear membrane+++GO:0032040///small-subunit processome+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome GO:0006364///rRNA processing 217116 217116 'Spata20' mRNA 3 2 2 0.06 0.04 0.05 0 0.02 0.04 0.05 0.02 0 1 2 2.333333333 1 0.614313191 -1.222675381 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0005975///carbohydrate metabolic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 217119 217119 'Xylt2' mRNA 737 670 184 11.72 10.48 3.1 3.57 7.27 7.28 8.433333333 6.04 258 514 510 530.3333333 427.3333333 0.747865658 -0.291036943 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000287///magnesium ion binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030158///protein xylosyltransferase activity+++GO:0046872///metal ion binding" GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0030210///heparin biosynthetic process+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process 217124 217124 'Ppp1r9b' mRNA 608 620 373 7.55 7.57 4.91 10.22 10.98 10.86 6.676666667 10.68666667 947 994 975 533.6666667 972 4.12E-10 0.86375877 GO:0001931///uropod+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005912///adherens junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044326///dendritic spine neck+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:1990780///cytoplasmic side of dendritic spine plasma membrane GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0031749///D2 dopamine receptor binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0001562///response to protozoan+++GO:0001808///negative regulation of type IV hypersensitivity+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001975///response to amphetamine+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0003006///developmental process involved in reproduction+++GO:0006468///protein phosphorylation+++GO:0007015///actin filament organization+++GO:0007162///negative regulation of cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007568///aging+++GO:0007612///learning+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0019722///calcium-mediated signaling+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030036///actin cytoskeleton organization+++GO:0030042///actin filament depolymerization+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0031175///neuron projection development+++GO:0031295///T cell costimulation+++GO:0032355///response to estradiol+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034695///response to prostaglandin E+++GO:0035094///response to nicotine+++GO:0035690///cellular response to drug+++GO:0035902///response to immobilization stress+++GO:0042102///positive regulation of T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0042493///response to drug+++GO:0042742///defense response to bacterium+++GO:0043200///response to amino acid+++GO:0045060///negative thymic T cell selection+++GO:0046847///filopodium assembly+++GO:0048545///response to steroid hormone+++GO:0050688///regulation of defense response to virus+++GO:0050776///regulation of immune response+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050863///regulation of T cell activation+++GO:0050868///negative regulation of T cell activation+++GO:0050901///leukocyte tethering or rolling+++GO:0060179///male mating behavior+++GO:0061458///reproductive system development+++GO:0071315///cellular response to morphine+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0097190///apoptotic signaling pathway+++GO:0097338///response to clozapine+++GO:1901653///cellular response to peptide+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903119///protein localization to actin cytoskeleton+++GO:1903829///positive regulation of cellular protein localization+++GO:1904372///positive regulation of protein localization to actin cortical patch+++GO:1904373///response to kainic acid+++GO:1904386///response to L-phenylalanine derivative+++GO:1990778///protein localization to cell periphery+++GO:2000404///regulation of T cell migration+++GO:2000406///positive regulation of T cell migration+++GO:2000474///regulation of opioid receptor signaling pathway 217125 217125 'Samd14' mRNA 394 420 322 6.37 6.64 5.49 4.8 4.17 3.85 6.166666667 4.273333333 347 286 273 378.6666667 302 0.034358628 -0.335435961 GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030425///dendrite GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0019722///calcium-mediated signaling+++GO:0031175///neuron projection development 217127 217127 'Kat7' mRNA 1586 1706 1705 24.74 26.39 28.46 19.74 20.64 18.71 26.53 19.69666667 1445 1476 1333 1665.666667 1418 0.00628842 -0.245325557 "GO:0000123///histone acetyltransferase complex+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0036409///histone H3-K14 acetyltransferase complex+++GO:0090734///site of DNA damage" "GO:0003688///DNA replication origin binding+++GO:0003712///transcription coregulator activity+++GO:0004402///histone acetyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding+++GO:0046872///metal ion binding" "GO:0001779///natural killer cell differentiation+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016573///histone acetylation+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0030174///regulation of DNA-dependent DNA replication initiation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072708///response to sorbitol+++GO:0072710///response to hydroxyurea+++GO:0072716///response to actinomycin D+++GO:0072720///response to dithiothreitol+++GO:0072739///response to anisomycin+++GO:0090240///positive regulation of histone H4 acetylation+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902035///positive regulation of hematopoietic stem cell proliferation+++GO:2000819///regulation of nucleotide-excision repair" 217138 217138 'Prr15l' mRNA 1627 1671 1599 60.97 61.1 62.94 37.36 38.53 36.9 61.67 37.59666667 1144 1146 1096 1632.333333 1128.666667 2.95E-12 -0.544019882 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 217140 217140 'Scrn2' mRNA 481 577 531 18.69 22.13 21.89 12.86 12.9 11.54 20.90333333 12.43333333 380 372 330 529.6666667 360.6666667 2.09E-05 -0.566774489 GO:0003674///molecular_function+++GO:0016805///dipeptidase activity+++GO:0070004///cysteine-type exopeptidase activity GO:0006508///proteolysis 217143 217143 'Gpr179' mRNA 208 262 228 1.31 1.64 1.55 0.72 0.59 0.69 1.5 0.666666667 130 105 122 232.6666667 119 5.98E-07 -0.979768745 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044292///dendrite terminus GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0072659///protein localization to plasma membrane 217149 217149 'Cisd3' mRNA 679 732 691 61.53 65.82 66.13 48.73 53.79 49.71 64.49333333 50.74333333 615 662 605 700.6666667 627.3333333 0.151859265 -0.170651477 GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle "GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0106034///protein maturation by [2Fe-2S] cluster transfer 217151 217151 'Arl5c' mRNA 17 20 21 0.64 0.74 0.84 2.63 2.49 3.26 0.74 2.793333333 80 73 96 19.33333333 83 1.50E-08 2.088574461 GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:1903292///protein localization to Golgi membrane 217154 217154 'Stac2' mRNA 6 10 4 0.11 0.18 0.08 0.78 0.72 0.57 0.123333333 0.69 50 45 35 6.666666667 43.33333333 2.17E-06 2.695717202 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042383///sarcolemma GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0003009///skeletal muscle contraction+++GO:0035556///intracellular signal transduction+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1903078///positive regulation of protein localization to plasma membrane 217166 217166 'Nr1d1' mRNA 2491.19 2395.81 2138.33 49.79 47.13 45.34 11.85 11.82 12.26 47.42 11.97666667 682.01 664.26 682.86 2341.776667 676.3766667 8.88E-121 -1.801941656 04710///Circadian rhythm GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0020037///heme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001678///cellular glucose homeostasis+++GO:0005978///glycogen biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007623///circadian rhythm+++GO:0009755///hormone-mediated signaling pathway+++GO:0010498///proteasomal protein catabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0031648///protein destabilization+++GO:0032922///circadian regulation of gene expression+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0042749///regulation of circadian sleep/wake cycle+++GO:0042752///regulation of circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044321///response to leptin+++GO:0045598///regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050728///negative regulation of inflammatory response+++GO:0060086///circadian temperature homeostasis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0061889///negative regulation of astrocyte activation+++GO:0070859///positive regulation of bile acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1903979///negative regulation of microglial cell activation+++GO:2000489///regulation of hepatic stellate cell activation" 217169 217169 'Tns4' mRNA 68 75 57 0.77 0.83 0.68 0.74 0.74 0.62 0.76 0.7 76 74 61 66.66666667 70.33333333 0.863090843 0.069112909 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0003779///actin binding GO:0006915///apoptotic process+++GO:0008104///protein localization 217194 217194 'Klhl11' mRNA 321 290 252 7.36 6.55 6.13 3.57 2.94 3.36 6.68 3.29 179 144 163 287.6666667 162 1.35E-06 -0.838532355 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 217198 217198 'Plekhh3' mRNA 396 332 77 7.13 5.91 1.46 1.12 2.58 2.17 4.833333333 1.956666667 71 161 134 268.3333333 122 0.177203893 -1.113735593 GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008150///biological_process 217201 217201 'Rundc1' mRNA 1347.44 1491.35 1388.88 22.89 24.93 25.03 18.74 15.8 15.44 24.28333333 16.66 1269.05 1045.19 1012.21 1409.223333 1108.816667 2.47E-04 -0.359175385 GO:0005096///GTPase activator activity GO:0001701///in utero embryonic development+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 217203 217203 'Tmem106a' mRNA 311 336 318 7.29 7.89 7.96 62.73 56.8 59.01 7.713333333 59.51333333 3087 2749 2814 321.6666667 2883.333333 2.51E-300 3.151706634 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035780///CD80 biosynthetic process+++GO:0035781///CD86 biosynthetic process+++GO:0042116///macrophage activation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0045087///innate immune response+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:1904407///positive regulation of nitric oxide metabolic process 217207 217207 'Dhx8' mRNA 642 649 646 7.99 7.95 8.53 8.41 8.13 7.96 8.156666667 8.166666667 778 734 713 645.6666667 741.6666667 0.09361263 0.187136327 03040///Spliceosome GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0000390///spliceosomal complex disassembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 217216 217216 'Hrob' mRNA 97 129 115 4.11 5.2 5.23 3.24 2.9 2.44 4.846666667 2.86 150 104 90 113.6666667 114.6666667 0.998591786 -0.003185233 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0090734///site of DNA damage GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding GO:0000725///recombinational repair+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007292///female gamete generation+++GO:0036297///interstrand cross-link repair+++GO:0048232///male gamete generation+++GO:0071897///DNA biosynthetic process 217217 217217 'Asb16' mRNA 12 14 12 0.23 0.27 0.25 0.05 0.1 0.19 0.25 0.113333333 3 6 11 12.66666667 6.666666667 0.321038798 -0.931404354 GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 217218 217218 'Atxn7l3' mRNA 352 330 282 5.4 5.09 4.62 4.69 4.76 4.39 5.036666667 4.613333333 355.1 350 322 321.3333333 342.3666667 0.658936642 0.082440359 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0071819///DUBm complex GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010390///histone monoubiquitination+++GO:0016578///histone deubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated" 217219 217219 'Fam171a2' mRNA 50 46 16 0.88 0.8 0.3 0.38 0.28 0.67 0.66 0.443333333 25 18 42 37.33333333 28.33333333 0.540679497 -0.391538716 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 217232 217232 'Cdc27' mRNA 761.75 707.59 698.78 7.1 6.44 6.86 7.33 7.03 7.22 6.8 7.193333333 875.6 824.83 805.87 722.7066667 835.4333333 0.061404183 0.197175128 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle GO:0019903///protein phosphatase binding GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 217246 217246 'Ace3' mRNA 4 1 0 0.08 0.02 0 0.02 0 0 0.033333333 0.006666667 1 0 0 1.666666667 0.333333333 0.51539789 -2.20073408 04614///Renin-angiotensin system+++04924///Renin secretion+++05142///Chagas disease+++05171///Coronavirus disease - COVID-19+++05410///Hypertrophic cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0008237///metallopeptidase activity+++GO:0008241///peptidyl-dipeptidase activity GO:0003081///regulation of systemic arterial blood pressure by renin-angiotensin+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006508///proteolysis 217258 217258 'Abca8a' mRNA 226 243 223 2.07 2.24 2.2 1.23 0.7 0.65 2.17 0.86 152 84 76 230.6666667 104 1.55E-06 -1.166230737 02010///ABC transporters GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006686///sphingomyelin biosynthetic process+++GO:0006869///lipid transport+++GO:0010874///regulation of cholesterol efflux+++GO:0010875///positive regulation of cholesterol efflux+++GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport 217262 217262 'Abca9' mRNA 358 369 358 2.62 2.66 2.82 6.28 5.48 5.81 2.7 5.856666667 988 841 882 361.6666667 903.6666667 8.89E-34 1.307972835 02010///ABC transporters GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0055085///transmembrane transport 217265 217265 'Abca5' mRNA 1386 1344 1203 8.86 8.44 8.16 3 2.67 2.65 8.486666667 2.773333333 539 469 463 1311 490.3333333 3.12E-52 -1.429699165 02010///ABC transporters GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0008203///cholesterol metabolic process+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010874///regulation of cholesterol efflux+++GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0042632///cholesterol homeostasis+++GO:0043691///reverse cholesterol transport+++GO:0055085///transmembrane transport+++GO:1903064///positive regulation of reverse cholesterol transport 217302 217302 'Gpr142' mRNA 4 4 1 0.24 0.24 0.06 0.32 0.22 0.11 0.18 0.216666667 6 4 2 3 4 0.821717602 0.416813438 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 217303 217303 'Cd300a' mRNA 35.22 45 38 1.04 1.3 1.16 19.24 19.46 17.76 1.166666667 18.82 751.15 740.2 669.32 39.40666667 720.2233333 5.04E-118 4.183389855 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001786///phosphatidylserine binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0019902///phosphatase binding+++GO:0038023///signaling receptor activity "GO:0002376///immune system process+++GO:0002552///serotonin secretion by mast cell+++GO:0006898///receptor-mediated endocytosis+++GO:0014063///negative regulation of serotonin secretion+++GO:0030889///negative regulation of B cell proliferation+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0033007///negative regulation of mast cell activation involved in immune response+++GO:0034125///negative regulation of MyD88-dependent toll-like receptor signaling pathway+++GO:0043305///negative regulation of mast cell degranulation+++GO:0043407///negative regulation of MAP kinase activity+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050859///negative regulation of B cell receptor signaling pathway+++GO:0051134///negative regulation of NK T cell activation+++GO:0060101///negative regulation of phagocytosis, engulfment+++GO:1902564///negative regulation of neutrophil activation+++GO:1902567///negative regulation of eosinophil activation+++GO:1902569///negative regulation of activation of Janus kinase activity+++GO:2000417///negative regulation of eosinophil migration" 217304 217304 'Cd300lb' mRNA 5 6 7 0.1 0.12 0.14 6.8 6.81 6.77 0.12 6.793333333 392 383 374 6 383 6.76E-56 5.984753019 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0002446///neutrophil mediated immunity+++GO:0033005///positive regulation of mast cell activation+++GO:0071222///cellular response to lipopolysaccharide 217305 217305 'Cd300ld' mRNA 10 25 23 0.23 0.56 0.56 15.57 14.79 16.38 0.45 15.58 782.64 726 797.33 19.33333333 768.6566667 4.00E-119 5.300430698 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0002376///immune system process+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0046718///viral entry into host cell 217306 217306 'Cd300e' mRNA 0 1 0 0 0.03 0 0.25 0.39 0.19 0.01 0.276666667 11 16 8 0.333333333 11.66666667 0.00161049 5.016376069 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity GO:0002376///immune system process+++GO:0008150///biological_process 217310 217310 'Hid1' mRNA 3198 3307 3170 51.1 52.48 54.33 33.04 35.31 34.61 52.63666667 34.32 2342 2445 2378 3225 2388.333333 2.05E-11 -0.444697353 GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0090498///extrinsic component of Golgi membrane GO:0003674///molecular_function 217316 217316 'Slc16a5' mRNA 18 7 5 0.45 0.16 0.15 0.37 0.16 0.3 0.253333333 0.276666667 20 9 15 10 14.66666667 0.563353238 0.546397037 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport 217325 217325 'Llgl2' mRNA 2597 2606 2392 39.78 39.3 38.93 17.86 17.53 18.16 39.33666667 17.85 1340 1286 1319 2531.666667 1315 1.59E-46 -0.955849824 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle GO:0005096///GTPase activator activity+++GO:0030165///PDZ domain binding+++GO:0045159///myosin II binding GO:0001890///placenta development+++GO:0006887///exocytosis+++GO:0007049///cell cycle+++GO:0008593///regulation of Notch signaling pathway+++GO:0009791///post-embryonic development+++GO:0015820///leucine transport+++GO:0016332///establishment or maintenance of polarity of embryonic epithelium+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032878///regulation of establishment or maintenance of cell polarity+++GO:0035264///multicellular organism growth+++GO:0050708///regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0051294///establishment of spindle orientation+++GO:0051301///cell division+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060716///labyrinthine layer blood vessel development 217328 217328 'Myo15b' mRNA 7514 7373 3636 39.69 38.27 25.15 2.44 2.99 2.9 34.37 2.776666667 529 630 610 6174.333333 589.6666667 2.88E-27 -3.382330081 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0016459///myosin complex GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding GO:0008150///biological_process 217331 217331 'Unk' mRNA 1346.48 1347.5 1314.51 19.58 19.24 20.22 12.77 11.5 12.05 19.68 12.10666667 1014 885.06 927 1336.163333 942.02 1.56E-09 -0.516767416 GO:0005737///cytoplasm+++GO:0005844///polysome GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:1905538///polysome binding+++GO:1990715///mRNA CDS binding GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0006417///regulation of translation+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:2000766///negative regulation of cytoplasmic translation 217333 217333 'Trim47' mRNA 230 223 116 5.92 5.65 3.16 9.46 18.37 13.77 4.91 13.86666667 423 802 596 189.6666667 607 3.53E-05 1.686944601 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination 217335 217335 'Fbf1' mRNA 978 934 893 9.4 8.82 9.25 5 4.8 4.62 9.156666667 4.806666667 594 555 536 935 561.6666667 1.72E-14 -0.746925189 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0036064///ciliary basal body+++GO:0043296///apical junction complex+++GO:0045095///keratin filament+++GO:0097539///ciliary transition fiber GO:0005515///protein binding GO:0030030///cell projection organization+++GO:0043297///apical junction assembly+++GO:0060271///cilium assembly+++GO:0090162///establishment of epithelial cell polarity 217337 217337 'Srp68' mRNA 1888 1996 1747 41.61 43.3 40.84 33.87 33.55 31.68 41.91666667 33.03333333 1768 1710 1601 1877 1693 0.043737905 -0.159135631 03060///Protein export "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0048500///signal recognition particle" GO:0003723///RNA binding+++GO:0005047///signal recognition particle binding+++GO:0008312///7S RNA binding+++GO:0019904///protein domain specific binding+++GO:0030942///endoplasmic reticulum signal peptide binding+++GO:0043022///ribosome binding GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0009410///response to xenobiotic stimulus+++GO:0042493///response to drug 217340 217340 'Rnf157' mRNA 629 637 603 7.18 7.17 7.33 1.2 1.12 1.3 7.226666667 1.206666667 120 111 126 623 119 1.49E-65 -2.399950027 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0044297///cell body GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008333///endosome to lysosome transport+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0051865///protein autoubiquitination+++GO:1903861///positive regulation of dendrite extension 217341 217341 'Qrich2' mRNA 5 2 0 0.11 0.05 0 0.09 0.02 0.02 0.053333333 0.043333333 4 1 3 2.333333333 2.666666667 0.927322679 0.199143384 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0031965///nuclear membrane+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030031///cell projection assembly+++GO:0030317///flagellated sperm motility+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 217342 217342 'Ube2o' mRNA 335 387 328 4.68 5.2 4.95 4.3 4.41 3.6 4.943333333 4.103333333 347 351 285 350 327.6666667 0.573678376 -0.105246992 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity "GO:0006513///protein monoubiquitination+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016567///protein ubiquitination+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043066///negative regulation of apoptotic process+++GO:0070534///protein K63-linked ubiquitination" 217344 217344 'Rhbdf2' mRNA 413 414 390 6.2 6.11 6.21 10.28 11.23 11.4 6.173333333 10.97 791 841 846 405.6666667 826 2.11E-21 1.015483349 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding GO:0006508///proteolysis+++GO:0015031///protein transport+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0050708///regulation of protein secretion+++GO:0050709///negative regulation of protein secretion 217351 217351 'Tnrc6c' mRNA 1562 1479 1411 9.62 8.98 9.25 6.35 5.17 5.88 9.283333333 5.8 1181 943 1062 1484 1062 4.26E-08 -0.495496569 GO:0000932///P-body+++GO:0005654///nucleoplasm GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0001706///endoderm formation+++GO:0006417///regulation of translation+++GO:0007492///endoderm development+++GO:0031047///gene silencing by RNA+++GO:0035162///embryonic hemopoiesis+++GO:0035195///gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0048568///embryonic organ development+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0060964///regulation of gene silencing by miRNA+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" 217353 217353 'Tmc6' mRNA 1326 1402 1273 25.39 26.28 25.92 22.93 21.13 22.51 25.86333333 22.19 1359 1247 1297 1333.666667 1301 0.647371644 -0.047156049 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 217356 217356 'Tmc8' mRNA 15 18 14 0.3 0.35 0.3 1.47 1.32 1.29 0.316666667 1.36 85 74 72 15.66666667 77 3.43E-09 2.286642825 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0008381///mechanosensitive ion channel activity+++GO:0043120///tumor necrosis factor binding GO:0001558///regulation of cell growth+++GO:0006811///ion transport+++GO:0031333///negative regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0034220///ion transmembrane transport+++GO:0055069///zinc ion homeostasis+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors 217364 217364 'Engase' mRNA 185 206 150 2.5 2.8 2.26 1.97 2.43 2.23 2.52 2.21 165 199 175 180.3333333 179.6666667 0.972425651 -0.010513153 00511///Other glycan degradation GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0033925///mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity" GO:0006517///protein deglycosylation+++GO:0008152///metabolic process 217365 217365 'Nploc4' mRNA 426 484 490 5.58 6.13 6.73 7.39 7.51 7.51 6.146666667 7.47 656 637 644 466.6666667 645.6666667 1.66E-04 0.454665551 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0036501///UFD1-NPL4 complex+++GO:0042175///nuclear outer membrane-endoplasmic reticulum membrane network GO:0031625///ubiquitin protein ligase binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007030///Golgi organization+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0032480///negative regulation of type I interferon production+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process" 217366 217366 'Lrrc45' mRNA 1236 1269 1247 27.98 28.29 29.95 17.4 18.4 17.18 28.74 17.66 884 913 845 1250.666667 880.6666667 5.67E-09 -0.518117008 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 217369 217369 'Uts2r' mRNA 1 2 0 0.03 0.07 0 0.09 0.03 0.03 0.033333333 0.05 3 1 1 1 1.666666667 0.800369356 0.744215152 04080///Neuroactive ligand-receptor interaction GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0001604///urotensin II receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity "GO:0003105///negative regulation of glomerular filtration+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0008217///regulation of blood pressure+++GO:0010841///positive regulation of circadian sleep/wake cycle, wakefulness+++GO:0030307///positive regulation of cell growth+++GO:0035811///negative regulation of urine volume+++GO:0035814///negative regulation of renal sodium excretion+++GO:0045766///positive regulation of angiogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0046005///positive regulation of circadian sleep/wake cycle, REM sleep+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0097746///regulation of blood vessel diameter" 217370 217370 'Cybc1' mRNA 646 766 685 15.23 17.94 16.96 23.29 22.06 24.16 16.71 23.17 1136 1050 1130 699 1105.333333 2.09E-11 0.649393692 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0045728///respiratory burst after phagocytosis 217371 217371 'Rab40b' mRNA 108 152 104 3.31 4.6 3.4 2.36 2.84 2.49 3.77 2.563333333 89 104 90 121.3333333 94.33333333 0.189003947 -0.368690046 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0072659///protein localization to plasma membrane+++GO:1901998///toxin transport 217378 217378 'Dnajc27' mRNA 510 471 521 5.96 5.32 6.32 2.59 2.53 3.1 5.866666667 2.74 248 239 278 500.6666667 255 1.84E-12 -0.987424251 GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0043410///positive regulation of MAPK cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071701///regulation of MAPK export from nucleus 217379 217379 'Ubxn2a' mRNA 2264.96 2415 1696.11 25.46 26.7 20.23 15.92 17.81 17.4 24.13 17.04333333 1630 1782 1726.04 2125.356667 1712.68 0.001917562 -0.315011565 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol GO:0033130///acetylcholine receptor binding+++GO:0043130///ubiquitin binding GO:0000045///autophagosome assembly+++GO:0007030///Golgi organization+++GO:0010468///regulation of gene expression+++GO:0031396///regulation of protein ubiquitination+++GO:0031468///nuclear envelope reassembly+++GO:0042176///regulation of protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0061025///membrane fusion+++GO:1990830///cellular response to leukemia inhibitory factor 217410 217410 'Trib2' mRNA 797 876 852 10.52 11.5 12.51 8.15 7.72 6.87 11.51 7.58 661 614 578 841.6666667 617.6666667 1.59E-05 -0.459753244 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0055106///ubiquitin-protein transferase regulator activity GO:0006468///protein phosphorylation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032693///negative regulation of interleukin-10 production+++GO:0043086///negative regulation of catalytic activity+++GO:0043405///regulation of MAP kinase activity+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045599///negative regulation of fat cell differentiation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity 21743 21743 'Inmt' mRNA 144 202 173 8.95 12.41 11.41 26.45 23.3 23.89 10.92333333 24.54666667 488 419 426 173 444.3333333 2.39E-17 1.34818595 00380///Tryptophan metabolism+++00450///Selenocompound metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004790///thioether S-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008170///N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0030748///amine N-methyltransferase activity+++GO:0098615///dimethyl selenide methyltransferase activity+++GO:0102707///S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity GO:0009308///amine metabolic process+++GO:0009636///response to toxic substance+++GO:0032259///methylation 217430 217430 'Pqlc3' mRNA 179 162 157 5.3 4.69 4.92 18.78 17.29 17.51 4.97 17.86 732 657 660 166 683 7.98E-55 2.028935406 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 217431 217431 'Nol10' mRNA 440.36 440.82 428.33 7.99 7.87 8.23 7.92 8.16 8.09 8.03 8.056666667 501.84 506.4 498.61 436.5033333 502.2833333 0.145413553 0.190814935 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 21744 21744 'Adad1' mRNA 4 3 0 0.12 0.09 0 0 0.03 0.03 0.07 0.02 0 1 1 2.333333333 0.666666667 0.511703938 -1.776499891 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity GO:0006382///adenosine to inosine editing+++GO:0006396///RNA processing+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation 217449 217449 'Trappc12' mRNA 1308 1210 1197 22.71 20.62 22.11 14.19 14.43 13.6 21.81333333 14.07333333 942 944 878 1238.333333 921.3333333 8.75E-07 -0.438226305 GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0030008///TRAPP complex+++GO:0048471///perinuclear region of cytoplasm GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0016192///vesicle-mediated transport+++GO:0051310///metaphase plate congression+++GO:0090234///regulation of kinetochore assembly+++GO:1905342///positive regulation of protein localization to kinetochore 21745 21745 'Tep1' mRNA 413 421 378 2.76 2.84 2.75 5.57 5.58 5.67 2.783333333 5.606666667 987 968 962 404 972.3333333 5.95E-37 1.256714974 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:1990904///ribonucleoprotein complex" GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0003720///telomerase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0019899///enzyme binding+++GO:0070034///telomerase RNA binding GO:0000722///telomere maintenance via recombination+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0007004///telomere maintenance via telomerase 217463 217463 'Snx13' mRNA 1457 1483 1453 11.91 11.93 12.68 10.41 11.23 10.78 12.17333333 10.80666667 1445 1517 1438 1464.333333 1466.666667 0.931787921 -0.009406931 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding GO:0006886///intracellular protein transport+++GO:0009968///negative regulation of signal transduction+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity 217473 217473 'Ankmy2' mRNA 819 764 785 18.68 17.17 19 13.27 12.73 13.36 18.28333333 13.12 669 627 652 789.3333333 649.3333333 0.005332412 -0.294541933 GO:0005575///cellular_component+++GO:0005929///cilium+++GO:0042995///cell projection GO:0019899///enzyme binding+++GO:0046872///metal ion binding 217480 217480 'Dgkb' mRNA 11 13 25 0.09 0.1 0.22 0.02 0 0.09 0.136666667 0.036666667 3 0 12 16.33333333 5 0.089751025 -1.739562753 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046339///diacylglycerol metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0099175///regulation of postsynapse organization 21749 21749 'Terf1' mRNA 466.22 476.31 393.09 11.6 11.67 10.39 8.07 7.15 8.44 11.22 7.886666667 372.94 322.7 377.99 445.2066667 357.8766667 0.018443192 -0.327252685 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0070187///shelterin complex" "GO:0003677///DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003720///telomerase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0008301///DNA binding, bending+++GO:0042162///telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0071532///ankyrin repeat binding+++GO:0098505///G-rich strand telomeric DNA binding" GO:0000237///leptotene+++GO:0000723///telomere maintenance+++GO:0007004///telomere maintenance via telomerase+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0031627///telomeric loop formation+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0042493///response to drug+++GO:0045141///meiotic telomere clustering+++GO:0051301///cell division+++GO:0051974///negative regulation of telomerase activity+++GO:0061820///telomeric D-loop disassembly+++GO:1904792///positive regulation of shelterin complex assembly+++GO:1904850///negative regulation of establishment of protein localization to telomere+++GO:1904911///negative regulation of establishment of RNA localization to telomere+++GO:1905778///negative regulation of exonuclease activity+++GO:1905839///negative regulation of telomeric D-loop disassembly 21750 21750 'Terf2' mRNA 260 280 247 6.64 6.94 6.61 6.58 5.86 5.89 6.73 6.11 296 260 267 262.3333333 274.3333333 0.803806485 0.053221094 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0030870///Mre11 complex+++GO:0070187///shelterin complex+++GO:1904115///axon cytoplasm" GO:0003677///DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003720///telomerase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0042162///telomeric DNA binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0098505///G-rich strand telomeric DNA binding "GO:0000723///telomere maintenance+++GO:0001701///in utero embryonic development+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0007049///cell cycle+++GO:0008089///anterograde axonal transport+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016233///telomere capping+++GO:0031627///telomeric loop formation+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0032204///regulation of telomere maintenance+++GO:0032205///negative regulation of telomere maintenance+++GO:0032206///positive regulation of telomere maintenance+++GO:0032208///negative regulation of telomere maintenance via recombination+++GO:0032210///regulation of telomere maintenance via telomerase+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0061820///telomeric D-loop disassembly+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0099087///anterograde axonal transport of messenger ribonucleoprotein complex+++GO:1903770///negative regulation of beta-galactosidase activity+++GO:1904354///negative regulation of telomere capping+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1904430///negative regulation of t-circle formation+++GO:1905778///negative regulation of exonuclease activity+++GO:1905839///negative regulation of telomeric D-loop disassembly+++GO:2000773///negative regulation of cellular senescence" 217517 217517 'Stxbp6' mRNA 1561 1560 1552 19.34 19.08 20.46 11.63 10.93 10.26 19.62666667 10.94 1080 992 926 1557.666667 999.3333333 1.75E-14 -0.653631609 GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding" GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0016192///vesicle-mediated transport+++GO:0035493///SNARE complex assembly+++GO:0035542///regulation of SNARE complex assembly 21752 21752 'Tert' mRNA 95 86 78 1.18 1.12 1.03 0.71 0.67 0.92 1.11 0.766666667 66 58 82 86.33333333 68.66666667 0.30007037 -0.340157702 05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer "GO:0000333///telomerase catalytic core complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0031379///RNA-directed RNA polymerase complex+++GO:0042645///mitochondrial nucleoid+++GO:1990572///TERT-RMRP complex" GO:0000049///tRNA binding+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003720///telomerase activity+++GO:0003721///telomerase RNA reverse transcriptase activity+++GO:0003723///RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003968///RNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042162///telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051087///chaperone binding+++GO:0070034///telomerase RNA binding+++GO:0098680///template-free RNA nucleotidyltransferase "GO:0001172///transcription, RNA-templated+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0007004///telomere maintenance via telomerase+++GO:0007005///mitochondrion organization+++GO:0010629///negative regulation of gene expression+++GO:0022616///DNA strand elongation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031647///regulation of protein stability+++GO:0032092///positive regulation of protein binding+++GO:0042635///positive regulation of hair cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0046326///positive regulation of glucose import+++GO:0046686///response to cadmium ion+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0060253///negative regulation of glial cell proliferation+++GO:0070200///establishment of protein localization to telomere+++GO:0071456///cellular response to hypoxia+++GO:0071897///DNA biosynthetic process+++GO:0090399///replicative senescence+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903620///positive regulation of transdifferentiation+++GO:1903704///negative regulation of production of siRNA involved in RNA interference+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2000648///positive regulation of stem cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 21753 21753 'Tes' mRNA 747 792 736 17.08 17.83 17.85 34.25 32.45 31.68 17.58666667 32.79333333 1723 1594 1543 758.3333333 1620 3.10E-39 1.083141193 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008285///negative regulation of cell proliferation+++GO:0042127///regulation of cell proliferation 21754 21754 'Tesk1' mRNA 238.08 268.02 228.92 3.57 3.95 3.64 4.7 4.35 4.62 3.72 4.556666667 361.08 326.28 343.49 245.0066667 343.6166667 0.001516551 0.478167874 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032880///regulation of protein localization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042326///negative regulation of phosphorylation+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051650///establishment of vesicle localization+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0090521///glomerular visceral epithelial cell migration+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902018///negative regulation of cilium assembly 217558 217558 'G2e3' mRNA 274 271 262 2.2 2.14 2.26 2.15 2.45 2.04 2.2 2.213333333 310 343 284 269 312.3333333 0.240346488 0.204616851 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0001824///blastocyst development+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 217578 217578 'Baz1a' mRNA 120 98 96 1.15 0.92 0.93 3.24 2.84 3.02 1 3.033333333 388 332 352 104.6666667 357.3333333 2.30E-24 1.759816669 GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0008623///CHRAC GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006261///DNA-dependent DNA replication+++GO:0006338///chromatin remodeling 217588 217588 'Mbip' mRNA 298 320 313 12.16 12.94 13.18 9.67 11.72 10.44 12.76 10.61 282 332 286 310.3333333 300 0.775037542 -0.060021703 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0010628///positive regulation of gene expression+++GO:0043086///negative regulation of catalytic activity+++GO:0043966///histone H3 acetylation+++GO:0046330///positive regulation of JNK cascade 217593 217593 'Slc25a21' mRNA 28 27 20 0.6 0.57 0.45 0.26 0.08 0.1 0.54 0.146666667 14 4 5 25 7.666666667 0.013653027 -1.719993918 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015139///alpha-ketoglutarate transmembrane transporter activity GO:1990550///mitochondrial alpha-ketoglutarate transmembrane transport 21761 21761 'Morf4l1' mRNA 3903.17 4079.45 2937.52 119.72 123.21 95.47 121.29 126.26 127.63 112.8 125.06 4556.54 4624.59 4641.66 3640.046667 4607.596667 7.30E-05 0.335240978 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0016580///Sin3 complex+++GO:0016607///nuclear speck+++GO:0035267///NuA4 histone acetyltransferase complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006342///chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0016573///histone acetylation+++GO:0016575///histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation" 21762 21762 'Psmd2' mRNA 4127 4251 4369 76.61 77.68 86.06 102.5 97.94 96.8 80.11666667 99.08 6352 5928 5808 4249 6029.333333 7.87E-14 0.490570184 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005838///proteasome regulatory particle+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0022624///proteasome accessory complex+++GO:0034515///proteasome storage granule" GO:0005515///protein binding+++GO:0030234///enzyme regulator activity GO:0042176///regulation of protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity 21763 21763 'Tex2' mRNA 1343 1266 1289 14.75 13.56 15.01 13.08 11.83 12.02 14.44 12.31 1382 1209 1221 1299.333333 1270.666667 0.693507542 -0.045777611 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process 217648 217648 'Gm527' mRNA 7 4 11 0.28 0.16 0.47 0.88 0.36 0.4 0.303333333 0.546666667 25 10 11 7.333333333 15.33333333 0.247433013 1.028047981 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 217653 217653 'Mis18bp1' mRNA 4 4 6 0.06 0.05 0.12 1.61 1.51 1.33 0.076666667 1.483333333 138 126 110 4.666666667 124.6666667 1.05E-22 4.725290058 "GO:0000775///chromosome, centromeric region+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0003677///DNA binding+++GO:0005515///protein binding GO:0007049///cell cycle+++GO:0051301///cell division 21766 21766 'Tex261' mRNA 2845 2919 2771 89.91 92.27 87.91 93.35 102.64 92.78 90.03 96.25666667 3412 3539 3255 2845 3402 2.68E-04 0.246717827 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0097020///COPII adaptor activity GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043065///positive regulation of apoptotic process 217664 217664 'Mgat2' mRNA 1165 1335 345 24.72 27.88 7.76 13.87 39.27 28.75 20.12 27.29666667 752 2079 1509 948.3333333 1446.666667 0.450921198 0.632969988 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008455///alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0009312///oligosaccharide biosynthetic process+++GO:0018279///protein N-linked glycosylation via asparagine 217666 217666 'L2hgdh' mRNA 472 421 465 7.71 6.77 8.06 7.44 7.22 6.95 7.513333333 7.203333333 524 497 474 452.6666667 498.3333333 0.405296034 0.124594453 00650///Butanoate metabolism GO:0005739///mitochondrion+++GO:0016021///integral component of membrane GO:0003973///(S)-2-hydroxy-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0047545///2-hydroxyglutarate dehydrogenase activity GO:0044267///cellular protein metabolic process 21767 21767 'Tex264' mRNA 2135 2164 2027 83.21 83.09 83.45 77.33 77.27 79.8 83.25 78.13333333 2273 2230 2265 2108.666667 2256 0.255786596 0.086277439 GO:0000421///autophagosome membrane+++GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0038023///signaling receptor activity GO:0006281///DNA repair+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:0061709///reticulophagy 217674 217674 'Gphb5' mRNA 5 1 0 0.2 0.04 0 0 0.04 0.11 0.08 0.05 0 1 3 2 1.333333333 0.858069997 -0.560563369 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005179///hormone activity+++GO:0031531///thyrotropin-releasing hormone receptor binding+++GO:0046982///protein heterodimerization activity GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway 217682 217682 'Plekhd1' mRNA 51 50 42 0.79 0.71 0.76 0.56 0.53 0.48 0.753333333 0.523333333 36 38 33 47.66666667 35.66666667 0.323098357 -0.42683578 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 217684 217684 'Susd6' mRNA 1958 2068 1579 20.97 21.7 17.93 20.92 26.26 24.45 20.2 23.87666667 2246 2758 2550 1868.333333 2518 1.48E-05 0.426006845 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death 21769 21769 'Zfand3' mRNA 650 699 421 12.71 13.26 8.32 11.3 10.63 12.06 11.43 11.33 652 605 680 590 645.6666667 0.468123812 0.127706366 GO:0005575///cellular_component GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 217692 217692 'Sipa1l1' mRNA 3183 3264 2809 22.47 22.7 20.7 12.11 10.39 10.82 21.95666667 11.10666667 2002 1636 1699 3085.333333 1779 1.69E-26 -0.805426541 04015///Rap1 signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0046875///ephrin receptor binding+++GO:0051015///actin filament binding GO:0031532///actin cytoskeleton reorganization+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0048167///regulation of synaptic plasticity+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0090630///activation of GTPase activity+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0099151///regulation of postsynaptic density assembly 217695 217695 'Zfyve1' mRNA 666.16 481.69 794.16 8.54 6.07 10.76 11.58 8.55 10.92 8.456666667 10.35 1041.44 751.03 956.77 647.3366667 916.4133333 0.121146212 0.475948906 04140///Autophagy - animal+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097629///extrinsic component of omegasome membrane+++GO:1990462///omegasome "GO:0005545///1-phosphatidylinositol binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046872///metal ion binding" GO:0009267///cellular response to starvation+++GO:0010923///negative regulation of phosphatase activity+++GO:0016236///macroautophagy+++GO:0140042///lipid droplet formation 217698 217698 'Acot5' mRNA 77.14 61.5 62.31 3.29 2.59 2.82 1.37 1.49 1.04 2.9 1.3 36.24 39.15 27.06 66.98333333 34.15 0.007560434 -0.982123928 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++04913///Ovarian steroidogenesis GO:0005777///peroxisome+++GO:0005829///cytosol GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0032788///saturated monocarboxylic acid metabolic process+++GO:0032789///unsaturated monocarboxylic acid metabolic process 21770 21770 'Ppp2r5d' mRNA 1407.96 1461.65 792.01 26.44 27.04 15.8 12.69 16.54 16.31 23.09333333 15.18 777.27 988.89 967.06 1220.54 911.0733333 0.183133275 -0.417620011 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0072542///protein phosphatase activator activity GO:0001932///regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010976///positive regulation of neuron projection development+++GO:0031952///regulation of protein autophosphorylation+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0071363///cellular response to growth factor stimulus 217700 217700 'Acot6' mRNA 133 96.14 108 2.7 1.88 2.31 1.73 1.45 1.86 2.296666667 1.68 104.15 78 101 112.38 94.38333333 0.380045345 -0.265873494 GO:0005777///peroxisome+++GO:0005829///cytosol GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process 217705 217705 'Fam161b' mRNA 334.68 363.62 330.25 5.89 6.59 6.6 1.97 1.79 2.43 6.36 2.063333333 121.87 113.32 148.21 342.85 127.8 4.98E-17 -1.437777854 GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton GO:0003674///molecular_function GO:0044782///cilium organization 217707 217707 'Coq6' mRNA 299 373 319 10.92 13.43 12.36 15.38 13.94 14.62 12.23666667 14.64666667 484 428 445 330.3333333 452.3333333 0.00160275 0.441858231 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0042995///cell projection "GO:0004497///monooxygenase activity+++GO:0008681///2-octaprenyl-6-methoxyphenol hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0006744///ubiquinone biosynthetic process 217708 217708 'Lin52' mRNA 859 869 864 22.88 22.64 24.38 15.63 15.76 16.08 23.3 15.82333333 693 671 671 864 678.3333333 2.75E-04 -0.361635813 04218///Cellular senescence GO:0005575///cellular_component+++GO:0070176///DRM complex GO:0003674///molecular_function "GO:0006351///transcription, DNA-templated+++GO:0008150///biological_process" 21771 21771 'Utp4' mRNA 672 637 613 16.81 15.69 16.27 16.66 19.14 18.04 16.25666667 17.94666667 766 859 803 640.6666667 809.3333333 0.002650579 0.327073396 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030686///90S preribosome+++GO:0032040///small-subunit processome+++GO:0034455///t-UTP complex "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006364///rRNA processing+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis" 217715 217715 'Eif2b2' mRNA 1001 1067 926 36.49 38.35 35.81 37.44 37.29 35.61 36.88333333 36.78 1180 1147 1086 998 1137.666667 0.053447058 0.178831337 05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0030424///axon GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding GO:0001541///ovarian follicle development+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0007417///central nervous system development+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0014003///oligodendrocyte development+++GO:0042552///myelination+++GO:0043434///response to peptide hormone+++GO:0044237///cellular metabolic process+++GO:0045773///positive regulation of axon extension+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway 217716 217716 'Mlh3' mRNA 622 635 587 5.94 5.97 5.95 3.61 2.91 3.52 5.953333333 3.346666667 435 343 412 614.6666667 396.6666667 1.29E-07 -0.644366088 03430///Mismatch repair GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0001673///male germ cell nucleus+++GO:0005654///nucleoplasm+++GO:0005712///chiasma+++GO:0032300///mismatch repair complex GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019237///centromeric DNA binding+++GO:0030983///mismatched DNA binding GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007130///synaptonemal complex assembly+++GO:0007140///male meiotic nuclear division+++GO:0007144///female meiosis I+++GO:0008104///protein localization 217718 217718 'Nek9' mRNA 871 966 792 8.69 9.48 8.55 8.51 8.3 8.9 8.906666667 8.57 969 922 982 876.3333333 957.6666667 0.267937736 0.118877932 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0051301///cell division 217721 217721 'Flvcr2' mRNA 116 104 101 1.96 1.62 1.7 1.64 1.61 1.44 1.76 1.563333333 119 114 101 107 111.3333333 0.879502333 0.045869757 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0022857///transmembrane transporter activity GO:0015886///heme transport+++GO:0055085///transmembrane transport+++GO:0097037///heme export 217732 217732 'Cipc' mRNA 2093 2287 2075 27.18 29.14 28.59 20.71 20.34 18.73 28.30333333 19.92666667 1834 1761 1618 2151.666667 1737.666667 3.03E-05 -0.319792374 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding "GO:0042754///negative regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 217733 217733 'Tmem63c' mRNA 62.2 54.47 48.18 0.51 0.4 0.42 0.2 0.19 0.13 0.443333333 0.173333333 29.82 26.39 18.83 54.95 25.01333333 0.004376892 -1.177990688 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005227///calcium activated cation channel activity+++GO:1990760///osmolarity-sensing cation channel activity GO:0003094///glomerular filtration+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 217734 217734 'Pomt2' mRNA 755.06 849.4 770.01 7.95 8.76 8.58 5.76 6.2 6.08 8.43 6.013333333 629.32 662.71 644.41 791.49 645.48 0.004353087 -0.305684143 00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0035269///protein O-linked mannosylation+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0097502///mannosylation+++GO:1904100///positive regulation of protein O-linked glycosylation 217737 217737 'Ahsa1' mRNA 2147.97 2208.98 2099 97.36 98.47 100.62 99 94.67 105.45 98.81666667 99.70666667 2516.96 2349 2587 2151.983333 2484.32 0.006784657 0.195505277 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0006457///protein folding+++GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity 217738 217738 'Ism2' mRNA 13 7 25 0.29 0.15 0.58 0.21 0.33 0.26 0.34 0.266666667 11 17 13 15 13.66666667 0.863090843 -0.165702258 GO:0003674///molecular_function GO:0008150///biological_process 217779 217779 'Lysmd1' mRNA 484 512 454 11.27 11.74 11.22 8.46 9.27 8.37 11.41 8.7 418 447 400 483.3333333 421.6666667 0.126670009 -0.206703189 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 21778 21778 'Tex9' mRNA 933.48 984.78 1007.02 10.33 10.61 11.51 4.2 3.96 3.81 10.81666667 3.99 433.68 403.56 383.91 975.0933333 407.05 1.58E-32 -1.276437898 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 21780 21780 'Tfam' mRNA 539 509 532 7.44 6.91 7.78 6.87 6.73 7.25 7.376666667 6.95 573 549 586 526.6666667 569.3333333 0.47752002 0.099382709 04371///Apelin signaling pathway+++05016///Huntington disease GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0032991///protein-containing complex+++GO:0042645///mitochondrial nucleoid "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001018///mitochondrial promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008301///DNA binding, bending+++GO:0031072///heat shock protein binding+++GO:0034246///mitochondrial sequence-specific DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006390///mitochondrial transcription+++GO:0006391///transcription initiation from mitochondrial promoter+++GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0045893///positive regulation of transcription, DNA-templated" 21781 21781 'Tfdp1' mRNA 517 507 380 11.33 10.93 8.88 14.19 11.39 13.97 10.38 13.18333333 743 585 711 468 679.6666667 5.91E-05 0.530304268 04110///Cell cycle+++04350///TGF-beta signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0008544///epidermis development+++GO:0043276///anoikis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0070345///negative regulation of fat cell proliferation+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2000278///regulation of DNA biosynthetic process" 217826 217826 'Kcnk13' mRNA 29 30 25 0.48 0.49 0.36 4.83 5.32 4.96 0.443333333 5.036666667 354 361 328 28 347.6666667 3.79E-57 3.624474362 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport 217827 217827 'Nrde2' mRNA 387 430 425 5.62 6.14 6.53 5.07 4.57 4.1 6.096666667 4.58 402 357 318 414 359 0.16060484 -0.219917842 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0000278///mitotic cell cycle+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0016246///RNA interference+++GO:0031048///chromatin silencing by small RNA+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0051301///cell division+++GO:1902369///negative regulation of RNA catabolic process 217830 217830 'Dglucy' mRNA 191 221 191 3.22 3.66 3.37 6.62 6.21 6.77 3.416666667 6.533333333 436 405 442 201 427.6666667 5.25E-14 1.078518833 00470///D-Amino acid metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0016829///lyase activity+++GO:0047820///D-glutamate cyclase activity GO:0006536///glutamate metabolic process 217835 217835 'Rin3' mRNA 221 248 143 2.76 3.06 1.9 4.67 4.19 4.98 2.573333333 4.613333333 415 369 424 204 402.6666667 2.25E-08 0.977779352 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0043025///neuronal cell body GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0002091///negative regulation of receptor internalization+++GO:0007165///signal transduction+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060755///negative regulation of mast cell chemotaxis+++GO:0097494///regulation of vesicle size 217837 217837 'Itpk1' mRNA 3036 3054 3025 58.6 58.02 61.94 32.78 33.57 33.09 59.52 33.14666667 1954 1954 1910 3038.333333 1939.333333 4.71E-23 -0.660091285 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000825///inositol tetrakisphosphate 6-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding+++GO:0047325///inositol tetrakisphosphate 1-kinase activity+++GO:0052725///inositol-1,3,4-trisphosphate 6-kinase activity+++GO:0052726///inositol-1,3,4-trisphosphate 5-kinase activity" GO:0016310///phosphorylation+++GO:0021915///neural tube development+++GO:0032957///inositol trisphosphate metabolic process+++GO:0052746///inositol phosphorylation+++GO:0070266///necroptotic process 217843 217843 'Unc79' mRNA 103.11 107.74 94.37 0.29 0.34 0.34 0.08 0.05 0.04 0.323333333 0.056666667 34.32 26.7 15.4 101.74 25.47333333 3.99E-09 -2.031782706 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0030534///adult behavior+++GO:0035264///multicellular organism growth+++GO:0048149///behavioral response to ethanol 217845 217845 'Ifi27l2b' mRNA 67 58 50 3.84 3.28 3.04 5.29 5.48 5.32 3.386666667 5.363333333 106 107 103 58.33333333 105.3333333 0.002560579 0.844100312 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0097190///apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway 217847 217847 'Serpina10' mRNA 0 3 0 0 0.12 0 0.04 0 0.03 0.04 0.023333333 1 0 1 1 0.666666667 0.880820218 -0.565049143 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008201///heparin binding+++GO:0030414///peptidase inhibitor activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 21785 21785 'Tff2' mRNA 1 0 0 0.14 0 0 0.12 0.12 0 0.046666667 0.08 1 1 0 0.333333333 0.666666667 0.863090843 0.881254164 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0031723///CXCR4 chemokine receptor binding GO:0008284///positive regulation of cell proliferation+++GO:0019722///calcium-mediated signaling+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030334///regulation of cell migration+++GO:0043031///negative regulation of macrophage activation+++GO:0050728///negative regulation of inflammatory response+++GO:0060455///negative regulation of gastric acid secretion+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 21786 21786 'Tff3' mRNA 27 28 41 5.31 5.53 8.57 4.16 3.76 2.35 6.47 3.423333333 24 21 13 32 19.33333333 0.182514268 -0.75040442 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0030141///secretory granule GO:0042802///identical protein binding GO:0010906///regulation of glucose metabolic process+++GO:0030277///maintenance of gastrointestinal epithelium 217864 217864 'Rcor1' mRNA 484 388 384 4.54 3.58 3.82 4.72 4.45 4.81 3.98 4.66 579 534 572 418.6666667 561.6666667 0.001632365 0.413035249 05016///Huntington disease GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:1990391///DNA repair complex GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression+++GO:0016575///histone deacetylation+++GO:0030218///erythrocyte differentiation+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation" 217866 217866 'Cdc42bpb' mRNA 1391.56 1309.06 1215.38 9.55 8.98 9.06 7.55 7.04 6.76 9.196666667 7.116666667 1209.24 1092.78 1051.06 1305.333333 1117.693333 0.008903064 -0.235265687 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0042641///actomyosin+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction 217869 217869 'Eif5' mRNA 4075 4299 4249 55.52 57.59 61.4 57.23 55.15 55.99 58.17 56.12333333 4835 4551 4580 4207.666667 4655.333333 0.05129585 0.132527835 04214///Apoptosis - fly GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005525///GTP binding+++GO:0071074///eukaryotic initiation factor eIF2 binding GO:0001731///formation of translation preinitiation complex+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0090630///activation of GTPase activity 21787 21787 'Tfg' mRNA 1793 1869.63 1761 52.23 53.73 54.35 54.75 54.58 56.12 53.43666667 55.15 2163 2101 2138 1807.876667 2134 0.001363831 0.227834859 05200///Pathways in cancer+++05216///Thyroid cancer GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048208///COPII vesicle coating 21788 21788 'Tfpi' mRNA 370 361 425 12.35 12.54 15.9 19.98 19.17 19.08 13.59666667 19.41 697 638 621 385.3333333 652 7.25E-09 0.742279032 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005901///caveola+++GO:0009986///cell surface GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030195///negative regulation of blood coagulation 217882 217882 'Cep170b' mRNA 1009 989 947 8.25 8.02 8.21 8.28 8.54 8.25 8.16 8.356666667 1164 1160 1117 981.6666667 1147 0.017594924 0.213254596 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0003674///molecular_function GO:0008150///biological_process 217887 217887 'Clba1' mRNA 517 531 528 15.45 15.63 16.73 11.05 11.47 9.16 15.93666667 10.56 425 431 341 525.3333333 399 0.002823673 -0.409637906 GO:0030121///AP-1 adaptor complex+++GO:0032588///trans-Golgi network membrane GO:0030276///clathrin binding GO:0046907///intracellular transport 21789 21789 'Tfpi2' mRNA 1 1 1 0.04 0.04 0.04 2 1.71 1.35 0.04 1.686666667 60 50 39 1 49.66666667 8.66E-09 5.621039919 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0071498///cellular response to fluid shear stress 217893 217893 'Pacs2' mRNA 953 1061 744 9.19 10.06 7.64 7.18 7.64 7.22 8.963333333 7.346666667 855 890 837 919.3333333 860.6666667 0.456722267 -0.100179978 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum GO:0044325///ion channel binding GO:0000045///autophagosome assembly+++GO:0006915///apoptotic process+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0034497///protein localization to phagophore assembly site+++GO:0072659///protein localization to plasma membrane+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering 217935 217935 'Wdr60' mRNA 1229 1058 1118 17.4 14.78 16.87 7.04 7.77 7.43 16.35 7.413333333 579 613 581 1135 591 6.40E-21 -0.953475215 GO:0000242///pericentriolar material+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005929///cilium+++GO:0031021///interphase microtubule organizing center+++GO:0042995///cell projection+++GO:0097014///ciliary plasm+++GO:0097546///ciliary base GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0007018///microtubule-based movement+++GO:0030030///cell projection organization+++GO:0035721///intraciliary retrograde transport+++GO:0042073///intraciliary transport+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0060271///cilium assembly 217944 217944 'Rapgef5' mRNA 1589 1584 1313 13.74 13.22 11.96 13.23 12.66 13.07 12.97333333 12.98666667 1779 1664 1707 1495.333333 1716.666667 0.021151566 0.190331244 04014///Ras signaling pathway+++04015///Rap1 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030742///GTP-dependent protein binding GO:0007264///small GTPase mediated signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 217946 217946 'Cdca7l' mRNA 260.35 296.82 264.01 5.44 5.86 5.85 7.97 8.05 6.9 5.716666667 7.64 451.92 440.44 375.41 273.7266667 422.59 2.14E-05 0.615244135 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation" 217951 217951 'Tmem196' mRNA 9 13 9 0.14 0.17 0.14 0.13 0.04 0.09 0.15 0.086666667 10 3 7 10.33333333 6.666666667 0.539908902 -0.646725943 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 217980 217980 'Larp4b' mRNA 1553.09 1620.91 1370.35 10.23 10.02 9.1 11.14 9.49 10.36 9.783333333 10.33 1978.31 1602.1 1800.74 1514.783333 1793.716667 0.008266658 0.233166969 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0042788///polysomal ribosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding GO:0006417///regulation of translation+++GO:0045727///positive regulation of translation+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization 217995 217995 'Heatr1' mRNA 244 300 247 1.9 2.3 2.04 3.99 3.7 3.59 2.08 3.76 589 534 514 263.6666667 545.6666667 5.58E-15 1.038557838 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030686///90S preribosome+++GO:0032040///small-subunit processome+++GO:0034455///t-UTP complex GO:0030515///snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:2000234///positive regulation of rRNA processing" 21802 21802 'Tgfa' mRNA 1893 2106 1586 22.51 24.7 19.82 9.25 11.07 9.87 22.34333333 10.06333333 896 1030 934 1861.666667 953.3333333 4.44E-24 -0.971034403 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04915///Estrogen signaling pathway+++05200///Pathways in cancer+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0042060///wound healing+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0048523///negative regulation of cellular process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051781///positive regulation of cell division+++GO:0060749///mammary gland alveolus development+++GO:0072574///hepatocyte proliferation 21803 21803 'Tgfb1' mRNA 3 5 1 0.08 0.13 0.03 0.47 0.46 0.86 0.08 0.596666667 21 20 37 3 26 1.16E-04 3.117170994 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04380///Osteoclast differentiation+++04390///Hippo signaling pathway+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++05140///Leishmaniasis+++05142///Chagas disease+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0031012///extracellular matrix+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix+++GO:0072562///blood microparticle GO:0003823///antigen binding+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019899///enzyme binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0034714///type III transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000902///cell morphogenesis+++GO:0001501///skeletal system development+++GO:0001570///vasculogenesis+++GO:0001657///ureteric bud development+++GO:0001666///response to hypoxia+++GO:0001763///morphogenesis of a branching structure+++GO:0001775///cell activation+++GO:0001837///epithelial to mesenchymal transition+++GO:0001843///neural tube closure+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002028///regulation of sodium ion transport+++GO:0002062///chondrocyte differentiation+++GO:0002069///columnar/cuboidal epithelial cell maturation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002362///CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment+++GO:0002460///adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains+++GO:0002513///tolerance induction to self antigen+++GO:0003179///heart valve morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0006468///protein phosphorylation+++GO:0006611///protein export from nucleus+++GO:0006754///ATP biosynthetic process+++GO:0006796///phosphate-containing compound metabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0007050///cell cycle arrest+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007183///SMAD protein complex assembly+++GO:0007219///Notch signaling pathway+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007435///salivary gland morphogenesis+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008354///germ cell migration+++GO:0009314///response to radiation+++GO:0009611///response to wounding+++GO:0009749///response to glucose+++GO:0009887///animal organ morphogenesis+++GO:0010033///response to organic substance+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010763///positive regulation of fibroblast migration+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010936///negative regulation of macrophage cytokine production+++GO:0014003///oligodendrocyte development+++GO:0014008///positive regulation of microglia differentiation+++GO:0014070///response to organic cyclic compound+++GO:0016202///regulation of striated muscle tissue development+++GO:0016477///cell migration+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0021915///neural tube development+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030214///hyaluronan catabolic process+++GO:0030217///T cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030308///negative regulation of cell growth+++GO:0030316///osteoclast differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030879///mammary gland development+++GO:0031065///positive regulation of histone deacetylation+++GO:0031100///animal organ regeneration+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0031334///positive regulation of protein complex assembly+++GO:0031536///positive regulation of exit from mitosis+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0032667///regulation of interleukin-23 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032801///receptor catabolic process+++GO:0032829///regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0032930///positive regulation of superoxide anion generation+++GO:0032943///mononuclear cell proliferation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033280///response to vitamin D+++GO:0034616///response to laminar fluid shear stress+++GO:0035066///positive regulation of histone acetylation+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035902///response to immobilization stress+++GO:0042060///wound healing+++GO:0042110///T cell activation+++GO:0042127///regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0042306///regulation of protein import into nucleus+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042482///positive regulation of odontogenesis+++GO:0042493///response to drug+++GO:0042552///myelination+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043117///positive regulation of vascular permeability+++GO:0043129///surfactant homeostasis+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043491///protein kinase B signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0043932///ossification involved in bone remodeling+++GO:0045066///regulatory T cell differentiation+++GO:0045216///cell-cell junction organization+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045918///negative regulation of cytolysis+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046716///muscle cell cellular homeostasis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048286///lung alveolus development+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0048535///lymph node development+++GO:0048565///digestive tract development+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048839///inner ear development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050765///negative regulation of phagocytosis+++GO:0050777///negative regulation of immune response+++GO:0050832///defense response to fungus+++GO:0050868///negative regulation of T cell activation+++GO:0050921///positive regulation of chemotaxis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051098///regulation of binding+++GO:0051101///regulation of DNA binding+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0055091///phospholipid homeostasis+++GO:0060325///face morphogenesis+++GO:0060364///frontal suture morphogenesis+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0060435///bronchiole development+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060751///branch elongation involved in mammary gland duct branching+++GO:0060762///regulation of branching involved in mammary gland duct morphogenesis+++GO:0060965///negative regulation of gene silencing by miRNA+++GO:0061035///regulation of cartilage development+++GO:0061448///connective tissue development+++GO:0070166///enamel mineralization+++GO:0070168///negative regulation of biomineral tissue development+++GO:0070306///lens fiber cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070723///response to cholesterol+++GO:0071260///cellular response to mechanical stimulus+++GO:0071363///cellular response to growth factor stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071479///cellular response to ionizing radiation+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071677///positive regulation of mononuclear cell migration+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0085029///extracellular matrix assembly+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097421///liver regeneration+++GO:0098586///cellular response to virus+++GO:1900126///negative regulation of hyaluronan biosynthetic process+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901666///positive regulation of NAD+ ADP-ribosyltransferase activity+++GO:1902074///response to salt+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1903911///positive regulation of receptor clustering+++GO:1904894///positive regulation of STAT cascade+++GO:1905005///regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905313///transforming growth factor beta receptor signaling pathway involved in heart development+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:1990402///embryonic liver development+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2000727///positive regulation of cardiac muscle cell differentiation" 218030 218030 'Pou6f2' mRNA 343 414 386 7.07 7.93 8.02 0.5 0.59 0.83 7.673333333 0.64 29 27 44 381 33.33333333 2.77E-55 -3.527074519 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development" 218035 218035 'Vps41' mRNA 2333 2377 2380 37.19 37.39 40.49 33.22 33.26 33.25 38.35666667 33.24333333 2369 2289 2283 2363.333333 2313.666667 0.631744214 -0.043623446 05132///Salmonella infection GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030897///HOPS complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0071439///clathrin complex+++GO:1902501///lysosomal HOPS complex GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding GO:0006623///protein targeting to vacuole+++GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0009267///cellular response to starvation+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0034058///endosomal vesicle fusion+++GO:0045055///regulated exocytosis+++GO:0046907///intracellular transport+++GO:0048193///Golgi vesicle transport+++GO:1902774///late endosome to lysosome transport 218038 218038 'Amph' mRNA 1237 1308 1310 20.06 21.1 22.81 4.98 3.73 3.99 21.32333333 4.233333333 347 252 268 1285 289 3.08E-77 -2.168272545 04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031256///leading edge membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0098793///presynapse+++GO:0098833///presynaptic endocytic zone+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008022///protein C-terminus binding+++GO:0044877///protein-containing complex binding GO:0007612///learning+++GO:0043547///positive regulation of GTPase activity+++GO:0045807///positive regulation of endocytosis+++GO:0048488///synaptic vesicle endocytosis 21804 21804 'Tgfb1i1' mRNA 239 234 224 4.89 4.59 4.92 9.07 9.58 11.18 4.8 9.943333333 350 362 422 232.3333333 378 5.98E-06 0.69168987 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016363///nuclear matrix+++GO:0030054///cell junction GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0048495///Roundabout binding+++GO:0050681///androgen receptor binding+++GO:0070411///I-SMAD binding "GO:0009408///response to heat+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016055///Wnt signaling pathway+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0030154///cell differentiation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0045165///cell fate commitment+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated" 21807 21807 'Tsc22d1' mRNA 2930 3081 2676 76.46 82.22 77.84 108.65 85.96 88.28 78.84 94.29666667 4150 3315 3451 2895.666667 3638.666667 5.20E-05 0.317644761 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II 21808 21808 'Tgfb2' mRNA 3637 3829 3489 35.65 37.03 36.55 21.63 22.45 21.88 36.41 21.98666667 2495 2505 2448 3651.666667 2482.666667 6.78E-21 -0.567382083 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04380///Osteoclast differentiation+++04390///Hippo signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05140///Leishmaniasis+++05142///Chagas disease+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0031012///extracellular matrix+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0034714///type III transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding GO:0000902///cell morphogenesis+++GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0001568///blood vessel development+++GO:0001654///eye development+++GO:0001666///response to hypoxia+++GO:0001822///kidney development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0003149///membranous septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003179///heart valve morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003274///endocardial cushion fusion+++GO:0003289///atrial septum primum morphogenesis+++GO:0003407///neural retina development+++GO:0006468///protein phosphorylation+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007411///axon guidance+++GO:0007435///salivary gland morphogenesis+++GO:0007507///heart development+++GO:0008219///cell death+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0008347///glial cell migration+++GO:0008584///male gonad development+++GO:0009410///response to xenobiotic stimulus+++GO:0009611///response to wounding+++GO:0010002///cardioblast differentiation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010936///negative regulation of macrophage cytokine production+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030097///hemopoiesis+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0030326///embryonic limb morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030509///BMP signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0031069///hair follicle morphogenesis+++GO:0032147///activation of protein kinase activity+++GO:0032570///response to progesterone+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032909///regulation of transforming growth factor beta2 production+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035910///ascending aorta morphogenesis+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042416///dopamine biosynthetic process+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0045216///cell-cell junction organization+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045726///positive regulation of integrin biosynthetic process+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045778///positive regulation of ossification+++GO:0045787///positive regulation of cell cycle+++GO:0045823///positive regulation of heart contraction+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048103///somatic stem cell division+++GO:0048566///embryonic digestive tract development+++GO:0048663///neuron fate commitment+++GO:0048666///neuron development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048839///inner ear development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050777///negative regulation of immune response+++GO:0050778///positive regulation of immune response+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051794///regulation of timing of catagen+++GO:0051795///positive regulation of timing of catagen+++GO:0051891///positive regulation of cardioblast differentiation+++GO:0060038///cardiac muscle cell proliferation+++GO:0060065///uterus development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060325///face morphogenesis+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0060413///atrial septum morphogenesis+++GO:0061037///negative regulation of cartilage development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0062009///secondary palate development+++GO:0070237///positive regulation of activation-induced cell death of T cells+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902256///regulation of apoptotic process involved in outflow tract morphogenesis+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903053///regulation of extracellular matrix organization+++GO:1903701///substantia propria of cornea development+++GO:1904238///pericyte cell differentiation+++GO:1904426///positive regulation of GTP binding+++GO:1904888///cranial skeletal system development+++GO:1905006///negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 21809 21809 'Tgfb3' mRNA 1585 1668 1665 25.52 26.42 28.43 26.68 30.33 26.93 26.79 27.98 1907 2118 1864 1639.333333 1963 0.005771349 0.247916074 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04110///Cell cycle+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05140///Leishmaniasis+++05142///Chagas disease+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0030315///T-tubule+++GO:0031012///extracellular matrix+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0034714///type III transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0050431///transforming growth factor beta binding "GO:0000187///activation of MAPK activity+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007435///salivary gland morphogenesis+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009790///embryo development+++GO:0009887///animal organ morphogenesis+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010936///negative regulation of macrophage cytokine production+++GO:0030501///positive regulation of bone mineralization+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030879///mammary gland development+++GO:0032570///response to progesterone+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0034616///response to laminar fluid shear stress+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043627///response to estrogen+++GO:0043932///ossification involved in bone remodeling+++GO:0045216///cell-cell junction organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0048565///digestive tract development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048839///inner ear development+++GO:0050714///positive regulation of protein secretion+++GO:0051491///positive regulation of filopodium assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051781///positive regulation of cell division+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0060364///frontal suture morphogenesis+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0062009///secondary palate development+++GO:0070483///detection of hypoxia+++GO:0071363///cellular response to growth factor stimulus+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905005///regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905075///positive regulation of tight junction disassembly" 21810 21810 'Tgfbi' mRNA 787 879 858 16.04 17.64 18.55 194.31 183.55 190.57 17.41 189.4766667 10967 10117 10414 841.3333333 10499.33333 0 3.628450873 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005802///trans-Golgi network+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005518///collagen binding+++GO:0042802///identical protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0050840///extracellular matrix binding GO:0001525///angiogenesis+++GO:0002062///chondrocyte differentiation+++GO:0007155///cell adhesion+++GO:0008283///cell proliferation+++GO:0030198///extracellular matrix organization 218100 218100 'Zfp322a' mRNA 535 640.01 563 5.8 6.79 6.48 5.84 5.52 5.67 6.356666667 5.676666667 621 573 588 579.3366667 594 0.867126887 0.024517123 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1902459///positive regulation of stem cell population maintenance" 218103 218103 'Slc17a2' mRNA 68 52 58 1.34 0.79 1.26 0.04 0.07 0.1 1.13 0.07 2 3 6 59.33333333 3.666666667 2.54E-11 -4.027592158 GO:0005764///lysosome+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015136///sialic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0015739///sialic acid transport+++GO:0055085///transmembrane transport 21812 21812 'Tgfbr1' mRNA 513.77 496.98 529 4.79 4.55 5.23 11.37 10.83 11.88 4.856666667 11.36 1408.02 1309 1424.74 513.25 1380.586667 1.12E-50 1.415291742 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04144///Endocytosis+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04390///Hippo signaling pathway+++04520///Adherens junction+++04659///Th17 cell differentiation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05142///Chagas disease+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0048179///activin receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005102///signaling receptor binding+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016361///activin receptor activity, type I+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding+++GO:0070411///I-SMAD binding" "GO:0000186///activation of MAPKK activity+++GO:0001501///skeletal system development+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001824///blastocyst development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002088///lens development in camera-type eye+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003342///proepicardium development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0008354///germ cell migration+++GO:0008584///male gonad development+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0009952///anterior/posterior pattern specification+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030154///cell differentiation+++GO:0030199///collagen fibril organization+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0031396///regulation of protein ubiquitination+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032924///activin receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042118///endothelial cell activation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043393///regulation of protein binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0043542///endothelial cell migration+++GO:0043627///response to estrogen+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0048538///thymus development+++GO:0048663///neuron fate commitment+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0048762///mesenchymal cell differentiation+++GO:0048844///artery morphogenesis+++GO:0048870///cell motility+++GO:0051272///positive regulation of cellular component movement+++GO:0051491///positive regulation of filopodium assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060017///parathyroid gland development+++GO:0060021///roof of mouth development+++GO:0060037///pharyngeal system development+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060412///ventricular septum morphogenesis+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0070723///response to cholesterol+++GO:0071363///cellular response to growth factor stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905075///positive regulation of tight junction disassembly+++GO:1905223///epicardium morphogenesis+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 218121 218121 'Mboat1' mRNA 1023 1029 1009 19.56 19.37 20.47 29.55 29.97 30.78 19.8 30.1 1778 1761 1793 1020.333333 1777.333333 1.33E-24 0.788767187 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010975///regulation of neuron projection development+++GO:0030258///lipid modification+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling 21813 21813 'Tgfbr2' mRNA 3015 3129 3080 34.04 34.76 36.93 52.22 52.93 54.78 35.24333333 53.31 5329 5276 5409 3074.666667 5338 4.15E-38 0.783443773 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04068///FoxO signaling pathway+++04144///Endocytosis+++04218///Cellular senescence+++04350///TGF-beta signaling pathway+++04380///Osteoclast differentiation+++04390///Hippo signaling pathway+++04520///Adherens junction+++04659///Th17 cell differentiation+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05142///Chagas disease+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0045121///membrane raft "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005026///transforming growth factor beta receptor activity, type II+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005539///glycosaminoglycan binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017002///activin-activated receptor activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0034714///type III transforming growth factor beta receptor binding+++GO:0038023///signaling receptor activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding" "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001947///heart looping+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002088///lens development in camera-type eye+++GO:0002651///positive regulation of tolerance induction to self antigen+++GO:0002663///positive regulation of B cell tolerance induction+++GO:0002666///positive regulation of T cell tolerance induction+++GO:0003148///outflow tract septum morphogenesis+++GO:0003149///membranous septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003186///tricuspid valve morphogenesis+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003274///endocardial cushion fusion+++GO:0003417///growth plate cartilage development+++GO:0003430///growth plate cartilage chondrocyte growth+++GO:0006468///protein phosphorylation+++GO:0006898///receptor-mediated endocytosis+++GO:0006915///apoptotic process+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007219///Notch signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007369///gastrulation+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007566///embryo implantation+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0008285///negative regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009749///response to glucose+++GO:0009887///animal organ morphogenesis+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0014070///response to organic cyclic compound+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0031100///animal organ regeneration+++GO:0032147///activation of protein kinase activity+++GO:0032924///activin receptor signaling pathway+++GO:0035162///embryonic hemopoiesis+++GO:0040008///regulation of growth+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043415///positive regulation of skeletal muscle tissue regeneration+++GO:0043627///response to estrogen+++GO:0045766///positive regulation of angiogenesis+++GO:0048545///response to steroid hormone+++GO:0048565///digestive tract development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0051138///positive regulation of NK T cell differentiation+++GO:0051216///cartilage development+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060412///ventricular septum morphogenesis+++GO:0060425///lung morphogenesis+++GO:0060433///bronchus development+++GO:0060434///bronchus morphogenesis+++GO:0060439///trachea morphogenesis+++GO:0060440///trachea formation+++GO:0060443///mammary gland morphogenesis+++GO:0060463///lung lobe morphogenesis+++GO:0062009///secondary palate development+++GO:0070723///response to cholesterol+++GO:0071363///cellular response to growth factor stimulus+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:1905315///cell proliferation involved in endocardial cushion morphogenesis+++GO:1905316///superior endocardial cushion morphogenesis+++GO:1905317///inferior endocardial cushion morphogenesis+++GO:1990086///lens fiber cell apoptotic process+++GO:1990428///miRNA transport+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation" 218138 218138 'Gmds' mRNA 408 435 396 15.98 16.8 16.47 15.82 16.85 16.06 16.41666667 16.24333333 464 482 456 413 467.3333333 0.226960782 0.167781272 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm "GO:0008446///GDP-mannose 4,6-dehydratase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0070401///NADP+ binding" GO:0007219///Notch signaling pathway+++GO:0019673///GDP-mannose metabolic process+++GO:0042351///'de novo' GDP-L-fucose biosynthetic process 21814 21814 'Tgfbr3' mRNA 2650 2599 2606 23.08 22.25 24.07 20.63 19.34 19.67 23.13333333 19.88 2728 2498 2520 2618.333333 2582 0.721771382 -0.033380061 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0034673///inhibin-betaglycan-ActRII complex+++GO:0043235///receptor complex "GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding+++GO:0015026///coreceptor activity+++GO:0017134///fibroblast growth factor binding+++GO:0030165///PDZ domain binding+++GO:0046332///SMAD binding+++GO:0048185///activin binding+++GO:0050431///transforming growth factor beta binding+++GO:0070123///transforming growth factor beta receptor activity, type III" GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001649///osteoblast differentiation+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001824///blastocyst development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001889///liver development+++GO:0001974///blood vessel remodeling+++GO:0003150///muscular septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003347///epicardial cell to mesenchymal cell transition+++GO:0006955///immune response+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007181///transforming growth factor beta receptor complex assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0016477///cell migration+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030509///BMP signaling pathway+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031100///animal organ regeneration+++GO:0032354///response to follicle-stimulating hormone+++GO:0032963///collagen metabolic process+++GO:0034695///response to prostaglandin E+++GO:0034699///response to luteinizing hormone+++GO:0035556///intracellular signal transduction+++GO:0043393///regulation of protein binding+++GO:0046328///regulation of JNK cascade+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051271///negative regulation of cellular component movement+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060021///roof of mouth development+++GO:0060038///cardiac muscle cell proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060216///definitive hemopoiesis+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060318///definitive erythrocyte differentiation+++GO:0060347///heart trabecula formation+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060412///ventricular septum morphogenesis+++GO:0060939///epicardium-derived cardiac fibroblast cell development+++GO:0060976///coronary vasculature development+++GO:0060977///coronary vasculature morphogenesis+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0061032///visceral serous pericardium development+++GO:0061384///heart trabecula morphogenesis+++GO:0062009///secondary palate development+++GO:0065003///protein-containing complex assembly+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0097746///regulation of blood vessel diameter+++GO:1902338///negative regulation of apoptotic process involved in morphogenesis 21815 21815 'Tgif1' mRNA 914 1005 975 32.35 35.25 36.65 43.83 51.03 48.35 34.75 47.73666667 1432 1586 1505 964.6666667 1507.666667 4.65E-12 0.632721683 04350///TGF-beta signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0070410///co-SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001843///neural tube closure+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007368///determination of left/right symmetry+++GO:0008285///negative regulation of cell proliferation+++GO:0009953///dorsal/ventral pattern formation+++GO:0010470///regulation of gastrulation+++GO:0010629///negative regulation of gene expression+++GO:0038092///nodal signaling pathway+++GO:0042493///response to drug+++GO:0045666///positive regulation of neuron differentiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0060041///retina development in camera-type eye+++GO:0071363///cellular response to growth factor stimulus" 21816 21816 'Tgm1' mRNA 23 28 12 0.46 0.56 0.25 2.09 1.61 1.96 0.423333333 1.886666667 120 91 109 21 106.6666667 2.71E-11 2.340452178 GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0031224///intrinsic component of membrane "GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0009887///animal organ morphogenesis+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0018149///peptide cross-linking+++GO:0019538///protein metabolic process+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0045787///positive regulation of cell cycle 218165 218165 'Ofcc1' mRNA 580 637 589 11.15 12.19 12.04 0.49 0.72 0.69 11.79333333 0.633333333 30 41 39 602 36.66666667 1.53E-99 -4.047878502 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 21817 21817 'Tgm2' mRNA 1282 1401 1269 19.63 21.1 20.61 71 70.09 73.15 20.44666667 71.41333333 5337 5146 5325 1317.333333 5269.333333 1.24E-227 1.988931007 05016///Huntington disease GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031226///intrinsic component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix "GO:0000166///nucleotide binding+++GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0008233///peptidase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050568///protein-glutamine glutaminase activity" GO:0001974///blood vessel remodeling+++GO:0006508///proteolysis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0018149///peptide cross-linking+++GO:0018153///isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine+++GO:0018277///protein deamination+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043277///apoptotic cell clearance+++GO:0043547///positive regulation of GTPase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050769///positive regulation of neurogenesis+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051260///protein homooligomerization+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0060348///bone development+++GO:0060445///branching involved in salivary gland morphogenesis+++GO:0060662///salivary gland cavitation+++GO:0071314///cellular response to cocaine+++GO:1903351///cellular response to dopamine+++GO:1904015///cellular response to serotonin+++GO:2000425///regulation of apoptotic cell clearance 21818 21818 'Tgm3' mRNA 2 3 1 0.04 0.04 0.02 0.02 0.06 0 0.033333333 0.026666667 1 3 0 2 1.333333333 0.835977722 -0.571935247 GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix "GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0003824///catalytic activity+++GO:0005198///structural molecule activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0008544///epidermis development+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0035315///hair cell differentiation+++GO:0043163///cell envelope organization+++GO:0043588///skin development 21819 21819 'Tg' mRNA 40 30 34 0.25 0.18 0.22 0.04 0.09 0.07 0.216666667 0.066666667 8 17 13 34.66666667 12.66666667 0.0079859 -1.460564348 04918///Thyroid hormone synthesis+++05320///Autoimmune thyroid disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0042802///identical protein binding+++GO:0043168///anion binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding GO:0006590///thyroid hormone generation+++GO:0007165///signal transduction+++GO:0009268///response to pH+++GO:0015705///iodide transport+++GO:0030878///thyroid gland development+++GO:0031641///regulation of myelination+++GO:0042403///thyroid hormone metabolic process+++GO:0042446///hormone biosynthetic process+++GO:0045056///transcytosis 218194 218194 'Phactr1' mRNA 857.53 891.76 823.8 7.34 7.8 7.4 7.73 8.34 8.64 7.513333333 8.236666667 1443.2 1516.32 1543.16 857.6966667 1500.893333 1.91E-21 0.797899086 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0045202///synapse GO:0003779///actin binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019888///protein phosphatase regulator activity GO:0021987///cerebral cortex development+++GO:0030036///actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0042325///regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0043149///stress fiber assembly+++GO:0048870///cell motility+++GO:0050790///regulation of catalytic activity+++GO:0140059///dendrite arborization+++GO:2001222///regulation of neuron migration 218203 218203 'Mylip' mRNA 1461 1593 1548 25.84 27.9 29.25 31.13 28.07 29.06 27.66333333 29.42 2052 1811 1870 1534 1911 2.13E-04 0.303385083 04979///Cholesterol metabolism GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007399///nervous system development+++GO:0010977///negative regulation of neuron projection development+++GO:0010989///negative regulation of low-density lipoprotein particle clearance+++GO:0016567///protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032803///regulation of low-density lipoprotein particle receptor catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0045732///positive regulation of protein catabolic process+++GO:0071404///cellular response to low-density lipoprotein particle stimulus 21821 21821 'Ift88' mRNA 667 644 548 12.04 11.54 10.55 5.97 5.59 5.09 11.37666667 5.55 371 348 318 619.6666667 345.6666667 2.36E-12 -0.85142974 GO:0002080///acrosomal membrane+++GO:0002081///outer acrosomal membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0060091///kinocilium+++GO:0097541///axonemal basal plate+++GO:0097542///ciliary tip+++GO:0097546///ciliary base+++GO:0097730///non-motile cilium GO:0005515///protein binding+++GO:0019894///kinesin binding GO:0001654///eye development+++GO:0001822///kidney development+++GO:0001886///endothelial cell morphogenesis+++GO:0001889///liver development+++GO:0003341///cilium movement+++GO:0007219///Notch signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007288///sperm axoneme assembly+++GO:0007290///spermatid nucleus elongation+++GO:0007368///determination of left/right symmetry+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008104///protein localization+++GO:0008544///epidermis development+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021537///telencephalon development+++GO:0030030///cell projection organization+++GO:0030324///lung development+++GO:0030900///forebrain development+++GO:0031016///pancreas development+++GO:0031122///cytoplasmic microtubule organization+++GO:0034405///response to fluid shear stress+++GO:0036334///epidermal stem cell homeostasis+++GO:0042073///intraciliary transport+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045598///regulation of fat cell differentiation+++GO:0048853///forebrain morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0055007///cardiac muscle cell differentiation+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060173///limb development+++GO:0060259///regulation of feeding behavior+++GO:0060271///cilium assembly+++GO:0060411///cardiac septum morphogenesis+++GO:0060426///lung vasculature development+++GO:0060914///heart formation+++GO:0061351///neural precursor cell proliferation+++GO:0070613///regulation of protein processing+++GO:0090102///cochlea development+++GO:1902017///regulation of cilium assembly+++GO:1903929///primary palate development+++GO:1905515///non-motile cilium assembly+++GO:2000785///regulation of autophagosome assembly 218210 218210 'Nup153' mRNA 755 845 726 7.13 7.88 7.55 5.1 5.44 5.11 7.52 5.216666667 582 593 572 775.3333333 582.3333333 5.58E-05 -0.422774634 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005642///annulate lamellae+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0034399///nuclear periphery+++GO:0042405///nuclear inclusion body+++GO:0044615///nuclear pore nuclear basket+++GO:1990875///nucleoplasmic side of nuclear pore GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0008270///zinc ion binding+++GO:0017056///structural constituent of nuclear pore+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043495///protein membrane anchor+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0051292///nuclear pore complex assembly 218214 218214 'Kdm1b' mRNA 344.1 374.31 337.08 3.96 4.22 3.98 4.53 4.28 4.42 4.053333333 4.41 465.65 449.15 437.83 351.83 450.8766667 0.008843881 0.345727342 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0034648///histone demethylase activity (H3-dimethyl-K4 specific)+++GO:0034649///histone demethylase activity (H3-monomethyl-K4 specific)+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0007275///multicellular organism development+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0043046///DNA methylation involved in gamete generation+++GO:0044030///regulation of DNA methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 218215 218215 'Rnf144b' mRNA 135 138 125 1.58 1.59 1.56 1.34 1.38 1.4 1.576666667 1.373333333 131 132 133 132.6666667 132 0.952426891 -0.017578903 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process 21822 21822 'Tgtp1' mRNA 422.75 470.4 356.34 8.31 9.1 7.43 6.54 6.22 5.25 8.28 6.003333333 383.03 355.69 297.57 416.4966667 345.43 0.076952698 -0.278230225 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0002376///immune system process+++GO:0006952///defense response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0045087///innate immune response 218232 218232 'Ptpdc1' mRNA 669 628 604 8.27 7.63 7.94 8.77 7.71 7.8 7.946666667 8.093333333 815 701 704 633.6666667 740 0.063578532 0.21141854 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007224///smoothened signaling pathway+++GO:0016311///dephosphorylation+++GO:0030030///cell projection organization+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0060271///cilium assembly 218236 218236 'Fam120a' mRNA 1873 1859 1754 19.4 18.94 19.27 22.2 20.23 22.33 19.20333333 21.58666667 2467 2197 2404 1828.666667 2356 5.19E-07 0.353608497 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003723///RNA binding 21824 21824 'Thbd' mRNA 202 184 179 2.94 2.64 2.77 11.56 9.36 10.02 2.783333333 10.31333333 913 722 766 188.3333333 800.3333333 3.95E-57 2.074219701 04610///Complement and coagulation cascades+++04933///AGE-RAGE signaling pathway in diabetic complications+++05418///Fluid shear stress and atherosclerosis GO:0005615///extracellular space+++GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016327///apicolateral plasma membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding GO:0007565///female pregnancy+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0009790///embryo development+++GO:0010165///response to X-ray+++GO:0030195///negative regulation of blood coagulation+++GO:0032496///response to lipopolysaccharide+++GO:0050819///negative regulation of coagulation+++GO:0051591///response to cAMP 21825 21825 'Thbs1' mRNA 1357 1315 1349 12.32 11.74 13 42.37 39.15 41.45 12.35333333 40.99 5371 4849 5090 1340.333333 5103.333333 6.35E-185 1.915371836 04015///Rap1 signaling pathway+++04115///p53 signaling pathway+++04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04350///TGF-beta signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05144///Malaria+++05165///Human papillomavirus infection+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05219///Bladder cancer GO:0005576///extracellular region+++GO:0005577///fibrinogen complex+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016529///sarcoplasmic reticulum+++GO:0030141///secretory granule+++GO:0031012///extracellular matrix+++GO:0031091///platelet alpha granule+++GO:0062023///collagen-containing extracellular matrix GO:0001786///phosphatidylserine binding+++GO:0001968///fibronectin binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0017134///fibroblast growth factor binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0043236///laminin binding+++GO:0050431///transforming growth factor beta binding+++GO:0050840///extracellular matrix binding+++GO:0070051///fibrinogen binding+++GO:0070052///collagen V binding GO:0000187///activation of MAPK activity+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0002040///sprouting angiogenesis+++GO:0002544///chronic inflammatory response+++GO:0002581///negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002605///negative regulation of dendritic cell antigen processing and presentation+++GO:0003151///outflow tract morphogenesis+++GO:0003197///endocardial cushion development+++GO:0003417///growth plate cartilage development+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006986///response to unfolded protein+++GO:0007050///cell cycle arrest+++GO:0007155///cell adhesion+++GO:0008284///positive regulation of cell proliferation+++GO:0009612///response to mechanical stimulus+++GO:0009749///response to glucose+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010748///negative regulation of plasma membrane long-chain fatty acid transport+++GO:0010751///negative regulation of nitric oxide mediated signal transduction+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0010757///negative regulation of plasminogen activation+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010763///positive regulation of fibroblast migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0016477///cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0018149///peptide cross-linking+++GO:0030194///positive regulation of blood coagulation+++GO:0030335///positive regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0032026///response to magnesium ion+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033574///response to testosterone+++GO:0034976///response to endoplasmic reticulum stress+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042327///positive regulation of phosphorylation+++GO:0042493///response to drug+++GO:0043032///positive regulation of macrophage activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0043652///engulfment of apoptotic cell+++GO:0045727///positive regulation of translation+++GO:0045766///positive regulation of angiogenesis+++GO:0048266///behavioral response to pain+++GO:0048514///blood vessel morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050921///positive regulation of chemotaxis+++GO:0051592///response to calcium ion+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051918///negative regulation of fibrinolysis+++GO:0070487///monocyte aggregation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0071732///cellular response to nitric oxide+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2001027///negative regulation of endothelial cell chemotaxis 21826 21826 'Thbs2' mRNA 92 86 95 0.82 0.76 0.9 3.65 3.44 3.48 0.826666667 3.523333333 469 432 433 91 444.6666667 6.45E-44 2.275274711 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05144///Malaria+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0031012///extracellular matrix+++GO:0031091///platelet alpha granule+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0007155///cell adhesion+++GO:0016525///negative regulation of angiogenesis+++GO:0051965///positive regulation of synapse assembly 21827 21827 'Thbs3' mRNA 32 27 40 0.55 0.45 0.73 1.98 2.24 2.18 0.576666667 2.133333333 133 147 142 33 140.6666667 5.32E-13 2.075846394 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05144///Malaria+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0008201///heparin binding GO:0003417///growth plate cartilage development+++GO:0007155///cell adhesion+++GO:0043931///ossification involved in bone maturation+++GO:0060346///bone trabecula formation 218271 218271 'B4galt7' mRNA 492.44 499.11 515.64 12.77 12.67 14.18 15.69 15.77 16.06 13.20666667 15.84 696.07 690.25 696.15 502.3966667 694.1566667 4.70E-05 0.454215237 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0046525///xylosylprotein 4-beta-galactosyltransferase activity+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006029///proteoglycan metabolic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0030166///proteoglycan biosynthetic process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0070085///glycosylation+++GO:0097435///supramolecular fiber organization 21828 21828 'Thbs4' mRNA 16 6 6 0.27 0.1 0.11 0 0.09 0.09 0.16 0.06 0 6 6 9.333333333 4 0.336216871 -1.213676981 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05144///Malaria+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0016529///sarcoplasmic reticulum+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0042802///identical protein binding+++GO:0043237///laminin-1 binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006986///response to unfolded protein+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0016525///negative regulation of angiogenesis+++GO:0034103///regulation of tissue remodeling+++GO:0034976///response to endoplasmic reticulum stress+++GO:0048266///behavioral response to pain+++GO:0048771///tissue remodeling+++GO:0048812///neuron projection morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051451///myoblast migration+++GO:0051781///positive regulation of cell division+++GO:0071603///endothelial cell-cell adhesion+++GO:0090023///positive regulation of neutrophil chemotaxis 218294 218294 'Cdc14b' mRNA 365.42 382.17 271 3.63 3.54 2.7 2.51 3.09 2.7 3.29 2.766666667 297 320 296.91 339.53 304.6366667 0.372992226 -0.16205253 04110///Cell cycle GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0072686///mitotic spindle GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006281///DNA repair+++GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007096///regulation of exit from mitosis+++GO:0016311///dephosphorylation+++GO:0032467///positive regulation of cytokinesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0060271///cilium assembly+++GO:0071850///mitotic cell cycle arrest+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:1904668///positive regulation of ubiquitin protein ligase activity 218311 218311 'Zfp455' mRNA 79.58 110.17 88.63 1.62 2.21 1.92 1.31 1.33 1.31 1.916666667 1.316666667 74 72.99 71.48 92.79333333 72.82333333 0.245010417 -0.3623046 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 218314 218314 'Zfp595' mRNA 117.62 119.42 117.19 1.6 1.6 1.7 1.68 1.41 1.4 1.633333333 1.496666667 142.05 116.58 116.98 118.0766667 125.2033333 0.829035313 0.069589299 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 21832 21832 'Thpo' mRNA 40 47 60 1 1.18 1.64 1.01 1.37 1.28 1.273333333 1.22 44 56 59 49 53 0.858756148 0.096560768 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004447///iodide peroxidase activity+++GO:0004601///peroxidase activity+++GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005179///hormone activity+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006590///thyroid hormone generation+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0030099///myeloid cell differentiation+++GO:0035162///embryonic hemopoiesis+++GO:0035855///megakaryocyte development+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0042446///hormone biosynthetic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0097696///STAT cascade+++GO:0098869///cellular oxidant detoxification+++GO:1902035///positive regulation of hematopoietic stem cell proliferation 21833 21833 'Thra' mRNA 1063.81 1027.19 781.67 22.92 21.9 18.33 10.3 9.49 11.27 21.05 10.35333333 546.99 496.74 573.14 957.5566667 538.9566667 2.59E-13 -0.836582183 04080///Neuroactive ligand-receptor interaction+++04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001161///intronic transcription regulatory region sequence-specific DNA binding+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003727///single-stranded RNA binding+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0017025///TBP-class protein binding+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0070324///thyroid hormone binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001502///cartilage condensation+++GO:0001503///ossification+++GO:0002154///thyroid hormone mediated signaling pathway+++GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007611///learning or memory+++GO:0008016///regulation of heart contraction+++GO:0008050///female courtship behavior+++GO:0009409///response to cold+++GO:0009755///hormone-mediated signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010831///positive regulation of myotube differentiation+++GO:0017055///negative regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0030878///thyroid gland development+++GO:0033032///regulation of myeloid cell apoptotic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045925///positive regulation of female receptivity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050994///regulation of lipid catabolic process+++GO:0060509///type I pneumocyte differentiation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2000143///negative regulation of DNA-templated transcription, initiation" 218333 218333 'Ice1' mRNA 396 394 416 2.69 2.62 2.99 2.63 2.41 2.01 2.766666667 2.35 444 399 339 402 394 0.831110956 -0.043872875 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0035327///transcriptionally active chromatin+++GO:0035363///histone locus body "GO:0030674///protein binding, bridging" GO:0031334///positive regulation of protein complex assembly+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0090316///positive regulation of intracellular protein transport 218335 218335 'Clptm1l' mRNA 1604 1674 567 37.75 38.79 14.15 22.16 24.79 28.51 30.23 25.15333333 1083 1183 1349 1281.666667 1205 0.898626932 -0.077250529 GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process 21834 21834 'Thrb' mRNA 360.87 337.74 413.76 2.76 2.63 3.65 1.34 1.18 1.18 3.013333333 1.233333333 199.81 173.81 165.45 370.79 179.69 2.86E-10 -1.065534448 04080///Neuroactive ligand-receptor interaction+++04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0016604///nuclear body GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001225///RNA polymerase II transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070324///thyroid hormone binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002154///thyroid hormone mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007605///sensory perception of sound+++GO:0007621///negative regulation of female receptivity+++GO:0008016///regulation of heart contraction+++GO:0008050///female courtship behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0009755///hormone-mediated signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0019216///regulation of lipid metabolic process+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0045778///positive regulation of ossification+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046549///retinal cone cell development+++GO:0060509///type I pneumocyte differentiation+++GO:0090181///regulation of cholesterol metabolic process+++GO:0090207///regulation of triglyceride metabolic process+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0097474///retinal cone cell apoptotic process" 218341 218341 'Rfesd' mRNA 384 382 325 8.67 8.44 7.78 5.91 5.4 5.73 8.296666667 5.68 303 270 284 363.6666667 285.6666667 0.014985284 -0.358086662 GO:0005575///cellular_component "GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0008150///biological_process 218343 218343 'Ttc37' mRNA 453 426 431 3.7 3.49 3.84 3.95 4.68 3.8 3.676666667 4.143333333 553 612 502 436.6666667 555.6666667 0.011485863 0.336255141 03018///RNA degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035327///transcriptionally active chromatin+++GO:0055087///Ski complex GO:0003674///molecular_function "GO:0006401///RNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'" 21835 21835 'Thrsp' mRNA 714 724 666 40.5 40.58 40.08 36.44 34.59 34.17 40.38666667 35.06666667 737 682 668 701.3333333 695.6666667 0.863090843 -0.023077923 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006629///lipid metabolic process+++GO:0009617///response to bacterium+++GO:0010866///regulation of triglyceride biosynthetic process+++GO:0046890///regulation of lipid biosynthetic process 21838 21838 'Thy1' mRNA 13 8 7 0.43 0.26 0.25 11.82 12.5 11.49 0.313333333 11.93666667 407 420 383 9.333333333 403.3333333 6.95E-65 5.423922648 04670///Leukocyte transendothelial migration GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030673///axolemma+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0005096///GTPase activator activity+++GO:0005178///integrin binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0034235///GPI anchor binding GO:0001525///angiogenesis+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002693///positive regulation of cellular extravasation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007267///cell-cell signaling+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0043113///receptor clustering+++GO:0043547///positive regulation of GTPase activity+++GO:0046549///retinal cone cell development+++GO:0046777///protein autophosphorylation+++GO:0048041///focal adhesion assembly+++GO:0050771///negative regulation of axonogenesis+++GO:0050852///T cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0070571///negative regulation of neuron projection regeneration+++GO:0098609///cell-cell adhesion+++GO:2000298///regulation of Rho-dependent protein serine/threonine kinase activity 218397 218397 'Rasa1' mRNA 559.86 508.24 447.34 6.19 5.52 5.23 5.95 4.72 5.29 5.646666667 5.32 624.14 483.28 542.72 505.1466667 550.0466667 0.467546661 0.112189922 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04360///Axon guidance GO:0001726///ruffle+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0001784///phosphotyrosine residue binding+++GO:0005096///GTPase activator activity+++GO:0005102///signaling receptor binding+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019900///kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0043422///protein kinase B binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding+++GO:1990782///protein tyrosine kinase binding GO:0001570///vasculogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0009410///response to xenobiotic stimulus+++GO:0030833///regulation of actin filament polymerization+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043087///regulation of GTPase activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0046326///positive regulation of glucose import+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048514///blood vessel morphogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0090630///activation of GTPase activity 21841 21841 'Tia1' mRNA 1637.14 1634.65 1495.94 19.28 19.02 18.39 15.75 14.69 14.39 18.89666667 14.94333333 1469.27 1360.93 1369 1589.243333 1399.733333 0.013378751 -0.194166647 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0097165///nuclear stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding "GO:0001818///negative regulation of cytokine production+++GO:0006915///apoptotic process+++GO:0017148///negative regulation of translation+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:1904037///positive regulation of epithelial cell apoptotic process" 21843 21843 'Tial1' mRNA 990 937 923 12.61 11.79 12.64 10.29 9.67 9.45 12.34666667 9.803333333 941 860 839 950 880 0.2476132 -0.122877777 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:1903231///mRNA binding involved in posttranscriptional gene silencing GO:0006915///apoptotic process+++GO:0007281///germ cell development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0016441///posttranscriptional gene silencing+++GO:0017145///stem cell division+++GO:0035332///positive regulation of hippo signaling+++GO:2000637///positive regulation of gene silencing by miRNA 21844 21844 'Tiam1' mRNA 705 634 529 5.31 4.75 3.98 3.2 2.59 2.89 4.68 2.893333333 493 390 425 622.6666667 436 6.21E-05 -0.523681738 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05205///Proteoglycans in cancer GO:0000242///pericentriolar material+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032587///ruffle membrane+++GO:0036477///somatodendritic compartment+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044291///cell-cell contact zone+++GO:0044295///axonal growth cone+++GO:0044304///main axon+++GO:0045202///synapse+++GO:0060091///kinocilium+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0019900///kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046875///ephrin receptor binding GO:0003300///cardiac muscle hypertrophy+++GO:0006915///apoptotic process+++GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0030335///positive regulation of cell migration+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0034622///cellular protein-containing complex assembly+++GO:0035556///intracellular signal transduction+++GO:0042220///response to cocaine+++GO:0043087///regulation of GTPase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0050772///positive regulation of axonogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0072657///protein localization to membrane+++GO:0090630///activation of GTPase activity+++GO:0098989///NMDA selective glutamate receptor signaling pathway+++GO:1904268///positive regulation of Schwann cell chemotaxis+++GO:1904338///regulation of dopaminergic neuron differentiation+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:1990138///neuron projection extension+++GO:2000050///regulation of non-canonical Wnt signaling pathway 218440 218440 'Ankrd34b' mRNA 8 9 11 0.11 0.12 0.15 0.05 0.05 0.07 0.126666667 0.056666667 4 4 6 9.333333333 4.666666667 0.337895893 -1.017002734 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 218441 218441 'Zfyve16' mRNA 744 734 680 7.27 7.05 7.05 5.01 4.98 5.22 7.123333333 5.07 591 574 596 719.3333333 587 0.003966501 -0.304058787 04144///Endocytosis+++04350///TGF-beta signaling pathway GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005545///1-phosphatidylinositol binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0046872///metal ion binding" GO:0006622///protein targeting to lysosome+++GO:0016197///endosomal transport 218442 218442 'Serinc5' mRNA 1456 1574 1439 14.59 15.51 15.29 13.48 12.67 13.08 15.13 13.07666667 1549 1422 1456 1489.666667 1475.666667 0.817765339 -0.025365492 GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0002376///immune system process+++GO:0006629///lipid metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009597///detection of virus+++GO:0042552///myelination+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:1904219///positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:1904222///positive regulation of serine C-palmitoyltransferase activity 218454 218454 'Lhfpl2' mRNA 1281 1424 1255 16.04 17.5 16.68 19.8 19.35 20.56 16.74 19.90333333 1821 1741 1829 1320 1797 1.33E-08 0.434361938 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007338///single fertilization+++GO:0046545///development of primary female sexual characteristics+++GO:0046546///development of primary male sexual characteristics+++GO:1905516///positive regulation of fertilization 21846 21846 'Tie1' mRNA 220 235 193 3.07 3.22 2.85 5.07 5.19 4.88 3.046666667 5.046666667 419 419 390 216 409.3333333 1.79E-10 0.913221919 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001936///regulation of endothelial cell proliferation+++GO:0003180///aortic valve morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0016310///phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0032526///response to retinoic acid+++GO:0033674///positive regulation of kinase activity+++GO:0045026///plasma membrane fusion+++GO:0045766///positive regulation of angiogenesis+++GO:0048771///tissue remodeling+++GO:0060836///lymphatic endothelial cell differentiation+++GO:0060854///branching involved in lymph vessel morphogenesis+++GO:1901201///regulation of extracellular matrix assembly 218460 218460 'Wdr41' mRNA 727.06 782.45 717.84 12.52 13.29 12.95 14.84 15.96 14.52 12.92 15.10666667 977.88 1030.28 918.25 742.45 975.47 1.11E-04 0.383291264 04140///Autophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:1990316///Atg1/ULK1 kinase complex GO:0005085///guanyl-nucleotide exchange factor activity GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0050790///regulation of catalytic activity 218461 218461 'Pde8b' mRNA 61.85 64.41 56.13 0.82 0.8 0.81 0.62 0.79 0.81 0.81 0.74 54.01 68.63 67.72 60.79666667 63.45333333 0.892638561 0.054384 00230///Purine metabolism+++04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++05032///Morphine addiction GO:0005575///cellular_component "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0001662///behavioral fear response+++GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0008542///visual learning+++GO:0035106///operant conditioning+++GO:0046676///negative regulation of insulin secretion+++GO:0050885///neuromuscular process controlling balance+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0090032///negative regulation of steroid hormone biosynthetic process 21847 21847 'Klf10' mRNA 809 859 753 14.5 15.17 14.33 25.54 24.69 23.86 14.66666667 24.69666667 1635 1545 1481 807 1553.666667 3.55E-30 0.934431735 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0009267///cellular response to starvation+++GO:0030282///bone mineralization+++GO:0035019///somatic stem cell population maintenance+++GO:0042752///regulation of circadian rhythm+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:1901653///cellular response to peptide" 218476 218476 'Gcnt4' mRNA 93 102 100 0.93 1.04 1.11 0.24 0.26 0.51 1.026666667 0.336666667 27 29 56 98.33333333 37.33333333 4.65E-05 -1.408321444 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003829///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0002121///inter-male aggressive behavior+++GO:0006486///protein glycosylation+++GO:0042403///thyroid hormone metabolic process+++GO:0048729///tissue morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0060993///kidney morphogenesis 21848 21848 'Trim24' mRNA 236 205 244 2.26 1.92 2.61 2.1 1.47 1.53 2.263333333 1.7 247 160 173 228.3333333 193.3333333 0.262029022 -0.259227186 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004672///protein kinase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016922///nuclear receptor binding+++GO:0034056///estrogen response element binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070577///lysine-acetylated histone binding "GO:0006468///protein phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0042981///regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0055074///calcium ion homeostasis+++GO:0070562///regulation of vitamin D receptor signaling pathway+++GO:0071391///cellular response to estrogen stimulus+++GO:1901796///regulation of signal transduction by p53 class mediator" 21849 21849 'Trim28' mRNA 1650.99 1604 861 27.83 26.6 15.39 15.58 19.94 20.37 23.27333333 18.63 1064 1330 1347 1371.996667 1247 0.747865658 -0.132651969 GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0035851///Krueppel-associated box domain binding+++GO:0046872///metal ion binding+++GO:0070087///chromo shadow domain binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0007566///embryo implantation+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043045///DNA methylation involved in embryo development+++GO:0043388///positive regulation of DNA binding+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045739///positive regulation of DNA repair+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060028///convergent extension involved in axis elongation+++GO:0060669///embryonic placenta morphogenesis+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:1901536///negative regulation of DNA demethylation+++GO:1902187///negative regulation of viral release from host cell+++GO:2000653///regulation of genetic imprinting" 218490 218490 'Btf3' mRNA 2376 2248 2144 176.5 165.37 169.04 245.65 240.34 251.07 170.3033333 245.6866667 3791 3615 3745 2256 3717 7.50E-31 0.709140526 04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005854///nascent polypeptide-associated complex+++GO:0042788///polysomal ribosome GO:0001701///in utero embryonic development+++GO:0015031///protein transport 218503 218503 'Fcho2' mRNA 908 930 804 9.49 9.55 8.92 9.31 9.57 9.59 9.32 9.49 1028 1032 1022 880.6666667 1027.333333 0.023402728 0.212847139 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0098835///presynaptic endocytic zone membrane "GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding" GO:0006897///endocytosis+++GO:0010324///membrane invagination+++GO:0048268///clathrin coat assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0072583///clathrin-dependent endocytosis+++GO:0072659///protein localization to plasma membrane 218506 218506 'Mrps27' mRNA 391 479 423 12.18 14.74 13.95 16.15 11.82 14.58 13.62333333 14.18333333 598 426 524 431 516 0.115254104 0.24571512 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0019843///rRNA binding+++GO:0097177///mitochondrial ribosome binding GO:0006417///regulation of translation+++GO:0008283///cell proliferation+++GO:0070131///positive regulation of mitochondrial translation 218518 218518 'Marveld2' mRNA 440 433 387 7.77 7.51 7.28 5.25 6.3 5.82 7.52 5.79 335 397 364 420 365.3333333 0.165050729 -0.209637202 04530///Tight junction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0033010///paranodal junction+++GO:0043220///Schmidt-Lanterman incisure+++GO:0061689///tricellular tight junction GO:0003674///molecular_function GO:0007605///sensory perception of sound+++GO:0045216///cell-cell junction organization+++GO:0061028///establishment of endothelial barrier+++GO:0070830///bicellular tight junction assembly 21853 21853 'Timeless' mRNA 91 123.07 134.09 1.04 1.37 1.63 6.11 5.28 5.58 1.346666667 5.656666667 587.13 495.04 522.99 116.0533333 535.0533333 5.11E-39 2.18770435 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0031298///replication fork protection complex+++GO:0035861///site of double-strand break GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000076///DNA replication checkpoint+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0002009///morphogenesis of an epithelium+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007623///circadian rhythm+++GO:0009790///embryo development+++GO:0030324///lung development+++GO:0042752///regulation of circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0043111///replication fork arrest+++GO:0044770///cell cycle phase transition+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048478///replication fork protection+++GO:0048511///rhythmic process+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0051301///cell division+++GO:0072711///cellular response to hydroxyurea+++GO:0072719///cellular response to cisplatin+++GO:1904976///cellular response to bleomycin+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2000781///positive regulation of double-strand break repair" 21854 21854 'Timm17a' mRNA 1457 1542 1475 103.89 108.83 111.6 112.53 128.59 119.95 108.1066667 120.3566667 1809 2015 1863 1491.333333 1895.666667 6.73E-05 0.335184478 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0008320///protein transmembrane transporter activity+++GO:0019899///enzyme binding GO:0010954///positive regulation of protein processing+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix 218543 218543 'Srek1' mRNA 1987 1823 1891 23.9 21.26 24.3 18.53 18.63 18.07 23.15333333 18.41 1760.98 1709 1667 1900.333333 1712.326667 0.049449518 -0.163449134 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000395///mRNA 5'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing" 218544 218544 'Sgtb' mRNA 97 109 101 1.67 1.85 1.85 1.32 1.21 1.41 1.79 1.313333333 88 79 91 102.3333333 86 0.37339334 -0.262995699 GO:0016020///membrane+++GO:0072380///TRC complex GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0060090///molecular adaptor activity GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1903646///positive regulation of chaperone-mediated protein folding 21855 21855 'Timm17b' mRNA 994.34 942.03 945.48 33.91 31.65 34.19 31.87 33.99 31.86 33.25 32.57333333 1074.69 1118.57 1039.58 960.6166667 1077.613333 0.125768227 0.153696645 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0008320///protein transmembrane transporter activity GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix 21856 21856 'Timm44' mRNA 898 950 992 29.08 30.32 34.08 31.9 30.25 31.88 31.16 31.34333333 1132 1048 1095 946.6666667 1091.666667 0.064263414 0.191144223 GO:0001650///fibrillar center+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019899///enzyme binding+++GO:0051087///chaperone binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix 21857 21857 'Timp1' mRNA 37 36 42 3.03 2.71 3.31 420.3 405.59 401.69 3.016666667 409.1933333 6432 6066 5941 38.33333333 6146.333333 0 7.313342803 04066///HIF-1 signaling pathway GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0004857///enzyme inhibitor activity+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008270///zinc ion binding+++GO:0030414///peptidase inhibitor activity+++GO:0046872///metal ion binding GO:0001775///cell activation+++GO:0002248///connective tissue replacement involved in inflammatory response wound healing+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0042060///wound healing+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043434///response to peptide hormone+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0051216///cartilage development+++GO:0071492///cellular response to UV-A+++GO:1901164///negative regulation of trophoblast cell migration+++GO:1905049///negative regulation of metallopeptidase activity+++GO:2001044///regulation of integrin-mediated signaling pathway 21858 21858 'Timp2' mRNA 2473 2431 2205 37.06 35.84 35.05 54.51 50.66 54.77 35.98333333 53.31333333 4187 3801 4074 2369.666667 4020.666667 2.98E-35 0.751890289 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0030426///growth cone+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0002020///protease binding+++GO:0004857///enzyme inhibitor activity+++GO:0005178///integrin binding+++GO:0008047///enzyme activator activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008270///zinc ion binding+++GO:0030414///peptidase inhibitor activity+++GO:0046872///metal ion binding GO:0007417///central nervous system development+++GO:0007568///aging+++GO:0008285///negative regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0032487///regulation of Rap protein signal transduction+++GO:0034097///response to cytokine+++GO:0042493///response to drug+++GO:0043408///regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0045861///negative regulation of proteolysis+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0071310///cellular response to organic substance+++GO:1905049///negative regulation of metallopeptidase activity 218581 218581 'Depdc1b' mRNA 2 1 3 0.04 0.02 0.08 0.91 0.59 0.84 0.046666667 0.78 48 31 43 2 40.66666667 3.65E-08 4.3262804 GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0016477///cell migration+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 21859 21859 'Timp3' mRNA 10887 11963 11631 124.6 134.64 141.2 119.48 114.56 113.13 133.48 115.7233333 12018 11257 11022 11493.66667 11432.33333 0.808596247 -0.021280843 05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0004857///enzyme inhibitor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0008270///zinc ion binding+++GO:0030414///peptidase inhibitor activity+++GO:0046872///metal ion binding GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0045861///negative regulation of proteolysis+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071310///cellular response to organic substance+++GO:1903984///positive regulation of TRAIL-activated apoptotic signaling pathway+++GO:1904684///negative regulation of metalloendopeptidase activity 218613 218613 'Mier3' mRNA 610 651 688 6.16 6.46 7.36 6.09 5.22 6.32 6.66 5.876666667 694 582 698 649.6666667 658 0.992518353 0.002928243 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003714///transcription corepressor activity+++GO:0042826///histone deacetylase binding GO:0000122///negative regulation of transcription by RNA polymerase II 218624 218624 'Il31ra' mRNA 15.34 10.14 15.83 0.16 0.11 0.19 0.19 0.1 0.09 0.153333333 0.126666667 20.28 10.57 9.03 13.77 13.29333333 0.94959695 -0.06039593 04060///Cytokine-cytokine receptor interaction GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding+++GO:0051916///granulocyte colony-stimulating factor binding GO:0002067///glandular epithelial cell differentiation+++GO:0002376///immune system process+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0007259///JAK-STAT cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030224///monocyte differentiation+++GO:0035745///T-helper 2 cell cytokine production+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0098542///defense response to other organism 218629 218629 'Dhx29' mRNA 519 489 510 6.25 5.79 6.52 5.62 5.25 4.91 6.186666667 5.26 537 490 454 506 493.6666667 0.767353314 -0.049345347 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0022627///cytosolic small ribosomal subunit "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003743///translation initiation factor activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008494///translation activator activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0017111///nucleoside-triphosphatase activity+++GO:0043024///ribosomal small subunit binding" GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0042255///ribosome assembly+++GO:0045948///positive regulation of translational initiation 218630 218630 'Ccno' mRNA 32 32 22 0.98 0.96 0.71 0.51 0.3 0.41 0.883333333 0.406666667 19 11 15 28.66666667 15 0.102220405 -0.942867383 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0097124///cyclin A2-CDK2 complex GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0030030///cell projection organization+++GO:0042493///response to drug+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:1903251///multi-ciliated epithelial cell differentiation 218639 218639 'Arl15' mRNA 1330.1 1175.9 1451.1 19.07 16.47 21.81 20.9 16.4 20.51 19.11666667 19.27 1719.8 1273.25 1637.25 1319.033333 1543.433333 0.113208145 0.207427496 GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008150///biological_process 21869 21869 'Nkx2-1' mRNA 7.45 16.85 8 0.15 0.34 0.16 0.09 0.06 0.07 0.216666667 0.073333333 4.81 3 4 10.76666667 3.936666667 0.154168943 -1.498642199 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001161///intronic transcription regulatory region sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017025///TBP-class protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0002016///regulation of blood volume by renin-angiotensin+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006644///phospholipid metabolic process+++GO:0007389///pattern specification process+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007492///endoderm development+++GO:0007626///locomotory behavior+++GO:0007631///feeding behavior+++GO:0009725///response to hormone+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0021537///telencephalon development+++GO:0021759///globus pallidus development+++GO:0021766///hippocampus development+++GO:0021795///cerebral cortex cell migration+++GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0021877///forebrain neuron fate commitment+++GO:0021879///forebrain neuron differentiation+++GO:0021892///cerebral cortex GABAergic interneuron differentiation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021983///pituitary gland development+++GO:0022029///telencephalon cell migration+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030336///negative regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030878///thyroid gland development+++GO:0030900///forebrain development+++GO:0031128///developmental induction+++GO:0032496///response to lipopolysaccharide+++GO:0033327///Leydig cell differentiation+++GO:0042538///hyperosmotic salinity response+++GO:0042696///menarche+++GO:0042753///positive regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048663///neuron fate commitment+++GO:0048709///oligodendrocyte differentiation+++GO:0060430///lung saccule development+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060486///Clara cell differentiation+++GO:0060510///type II pneumocyte differentiation" 218693 218693 'Paip1' mRNA 1875 1782 1834 22.55 21.08 23.43 14.73 13.89 14.84 22.35333333 14.48666667 1409 1297 1375 1830.333333 1360.333333 2.18E-08 -0.441486471 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008494///translation activator activity GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation 218695 218695 'Gm10044' mRNA 420 340 341 4.43 3.53 3.83 0.8 0.64 0.74 3.93 0.726666667 87 68 77 367 77.33333333 6.55E-34 -2.258773573 218699 218699 'Pxk' mRNA 1221 1201 1042 24.08 23.27 21.62 22.92 27.32 24.5 22.99 24.91333333 1348 1525 1382 1154.666667 1418.333333 0.001915133 0.288673822 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0035091///phosphatidylinositol binding GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0032780///negative regulation of ATPase activity+++GO:0042391///regulation of membrane potential+++GO:0043271///negative regulation of ion transport+++GO:0050804///modulation of chemical synaptic transmission 21871 21871 'Atp6v0a2' mRNA 1411 1476 1468 14.07 14.47 15.52 25.27 23.69 24.91 14.68666667 24.62333333 2918 2673 2787 1451.666667 2792.666667 6.11E-39 0.930581197 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0001669///acrosomal vesicle+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0043229///intracellular organelle+++GO:0048471///perinuclear region of cytoplasm" "GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007035///vacuolar acidification+++GO:0036295///cellular response to increased oxygen levels+++GO:1902600///proton transmembrane transport 21872 21872 'Tjp1' mRNA 3376 3333 3112 25.52 24.92 25.09 22.33 20.82 22.13 25.17666667 21.76 3378 3080 3242 3273.666667 3233.333333 0.724686011 -0.029422741 04520///Adherens junction+++04530///Tight junction+++04540///Gap junction+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005921///gap junction+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0031674///I band+++GO:0032991///protein-containing complex+++GO:0043296///apical junction complex+++GO:0045177///apical part of cell+++GO:0046581///intercellular canaliculus+++GO:0070160///tight junction GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0050839///cell adhesion molecule binding+++GO:0071253///connexin binding GO:0001825///blastocyst formation+++GO:0007605///sensory perception of sound+++GO:0008284///positive regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0031032///actomyosin structure organization+++GO:0032496///response to lipopolysaccharide+++GO:0034334///adherens junction maintenance+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043116///negative regulation of vascular permeability+++GO:0045216///cell-cell junction organization+++GO:0045471///response to ethanol+++GO:0051493///regulation of cytoskeleton organization+++GO:0051497///negative regulation of stress fiber assembly+++GO:0071000///response to magnetism+++GO:0071333///cellular response to glucose stimulus+++GO:0071896///protein localization to adherens junction+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0098609///cell-cell adhesion+++GO:1901888///regulation of cell junction assembly+++GO:1902396///protein localization to bicellular tight junction+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1905605///positive regulation of maintenance of permeability of blood-brain barrier+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:2000250///negative regulation of actin cytoskeleton reorganization+++GO:2000810///regulation of bicellular tight junction assembly 21873 21873 'Tjp2' mRNA 2361 2400 2363 27.03 27.03 28.65 18.35 17.07 18.43 27.57 17.95 1863 1694 1801 2374.666667 1786 2.48E-09 -0.42401292 04530///Tight junction+++05110///Vibrio cholerae infection GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005921///gap junction+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0044291///cell-cell contact zone+++GO:0070160///tight junction "GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0050839///cell adhesion molecule binding+++GO:1990782///protein tyrosine kinase binding" GO:0010033///response to organic substance+++GO:0034109///homotypic cell-cell adhesion+++GO:0045216///cell-cell junction organization+++GO:0050892///intestinal absorption+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0090559///regulation of membrane permeability+++GO:0098609///cell-cell adhesion+++GO:1905605///positive regulation of maintenance of permeability of blood-brain barrier+++GO:2001205///negative regulation of osteoclast development 218734 218734 '3830406C13Rik' mRNA 1190.39 1220.06 1217.86 28.82 29.68 30.77 21.6 21.05 19.75 29.75666667 20.8 1003.96 941.79 879.07 1209.436667 941.6066667 4.60E-05 -0.374857047 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 218756 218756 'Slc4a7' mRNA 278 340 259 2 2.38 1.97 2.75 2.02 2.75 2.116666667 2.506666667 441 317 428 292.3333333 395.3333333 0.011537222 0.425069091 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005452///inorganic anion exchanger activity+++GO:0005515///protein binding+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0007601///visual perception+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0021747///cochlear nucleus development+++GO:0035725///sodium ion transmembrane transport+++GO:0046666///retinal cell programmed cell death+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0060117///auditory receptor cell development+++GO:0060219///camera-type eye photoreceptor cell differentiation+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0098656///anion transmembrane transport 218763 218763 'Lrrc3b' mRNA 22 34 17 0.72 1.18 0.6 0.15 0.21 0.04 0.833333333 0.133333333 5 6 2 24.33333333 4.333333333 9.95E-04 -2.489864276 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0008150///biological_process 21877 21877 'Tk1' mRNA 23.15 25.11 25.67 1.02 1.06 1.15 16.07 16.25 16 1.076666667 16.10666667 420.96 416.97 407.86 24.64333333 415.2633333 5.07E-72 4.078402781 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004797///thymidine kinase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0009157///deoxyribonucleoside monophosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046104///thymidine metabolic process+++GO:0051289///protein homotetramerization+++GO:0071897///DNA biosynthetic process 218772 218772 'Rarb' mRNA 2084 1944 2191 38 34.8 42.4 10.65 10.8 11.19 38.4 10.88 673 668 681 2073 674 2.85E-70 -1.635860728 05200///Pathways in cancer+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:1901363///heterocyclic compound binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0002068///glandular epithelial cell development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003406///retinal pigment epithelium development+++GO:0003417///growth plate cartilage development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009755///hormone-mediated signaling pathway+++GO:0021756///striatum development+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0031641///regulation of myelination+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043068///positive regulation of programmed cell death+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048048///embryonic eye morphogenesis+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048566///embryonic digestive tract development+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:0060041///retina development in camera-type eye+++GO:0060348///bone development+++GO:0061037///negative regulation of cartilage development+++GO:0061351///neural precursor cell proliferation" 218793 218793 'Ube2e2' mRNA 983 986 837 39.51 39.01 35.58 14.46 15.42 13.76 38.03333333 14.54666667 418 430 384 935.3333333 410.6666667 4.35E-30 -1.196281947 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0042296///ISG15 transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0032020///ISG15-protein conjugation+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 21881 21881 'Tkt' mRNA 4495 4768 4439 76.14 79.46 79.76 86.41 84.73 87.52 78.45333333 86.22 5870 5622 5758 4567.333333 5750 7.58E-09 0.320553747 00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005654///nucleoplasm+++GO:0005777///peroxisome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016604///nuclear body+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004802///transketolase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0030976///thiamine pyrophosphate binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding "GO:0006098///pentose-phosphate shunt+++GO:0009052///pentose-phosphate shunt, non-oxidative branch+++GO:0040008///regulation of growth+++GO:0046166///glyceraldehyde-3-phosphate biosynthetic process+++GO:0046390///ribose phosphate biosynthetic process" 218811 218811 'Sec24c' mRNA 3042 3278 3402 36.43 38.61 43.41 38.29 35.65 35.93 39.48333333 36.62333333 3675 3350 3327 3240.666667 3450.666667 0.416564064 0.075391407 04141///Protein processing in endoplasmic reticulum+++05130///Pathogenic Escherichia coli infection GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0070971///endoplasmic reticulum exit site GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding GO:0001701///in utero embryonic development+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0090110///cargo loading into COPII-coated vesicle 218820 218820 'Zfp503' mRNA 48 36 36 0.61 0.45 0.49 0.68 0.59 0.62 0.516666667 0.63 61 52 54 40 55.66666667 0.246486992 0.46546171 GO:0005634///nucleus GO:0046872///metal ion binding+++GO:0070491///repressing transcription factor binding "GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0061351///neural precursor cell proliferation+++GO:0070315///G1 to G0 transition involved in cell differentiation" 218832 218832 'Polr3a' mRNA 443 447 400 5.05 5.07 4.84 4.96 4.61 3.99 4.986666667 4.52 500 450 390 430 446.6666667 0.815135811 0.043557031 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity "GO:0006351///transcription, DNA-templated+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response" 21885 21885 'Tle1' mRNA 806 827 704 6.56 6.38 5.04 8.33 7.6 7.18 5.993333333 7.703333333 1204 1138 1147 779 1163 8.33E-11 0.568495829 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway+++04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990907///beta-catenin-TCF complex GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0070491///repressing transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000811///negative regulation of anoikis" 218850 218850 'Tasor' mRNA 1154.96 1277.74 860.6 8.12 8.79 6.35 3.86 4.51 4.35 7.753333333 4.24 637.34 728.9 695.64 1097.766667 687.2933333 1.99E-08 -0.67883562 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003682///chromatin binding+++GO:0005515///protein binding "GO:0001701///in utero embryonic development+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0060809///mesodermal to mesenchymal transition involved in gastrulation+++GO:0090307///mitotic spindle assembly+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0097355///protein localization to heterochromatin" 21886 21886 'Tle2' mRNA 875 893 756 16.08 16.25 14.83 12.15 11.83 11.3 15.72 11.76 765 724 677 841.3333333 722 0.028283067 -0.230233059 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway+++04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005925///focal adhesion+++GO:0016604///nuclear body GO:0003714///transcription corepressor activity+++GO:0070491///repressing transcription factor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 218865 218865 'Chdh' mRNA 989.34 988.63 854.84 9.31 9.18 8.53 9.94 7.14 8.92 9.006666667 8.666666667 1216.83 853.72 1052.02 944.27 1040.856667 0.333758184 0.128527251 "00260///Glycine, serine and threonine metabolism" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane "GO:0008812///choline dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016614///oxidoreductase activity, acting on CH-OH group of donors+++GO:0050660///flavin adenine dinucleotide binding" GO:0019285///glycine betaine biosynthetic process from choline 21887 21887 'Tle3' mRNA 1661 1545 901 17.11 15.64 9.85 6.81 7.5 8 14.2 7.436666667 761 818 868 1369 815.6666667 0.004485489 -0.745264189 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway+++04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:1990907///beta-catenin-TCF complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0070491///repressing transcription factor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis" 218877 218877 'Sema3g' mRNA 83 59 41 1.03 0.72 0.54 0.89 0.7 0.74 0.763333333 0.776666667 84 64 65 61 71 0.614788136 0.213469432 04360///Axon guidance GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane GO:0005102///signaling receptor binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 21888 21888 'Tle4' mRNA 570 599 521 7.2 7.4 7.06 5.64 4.7 5.43 7.22 5.256666667 521 415 460 563.3333333 465.3333333 0.023878409 -0.287275701 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway+++04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990907///beta-catenin-TCF complex "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1990830///cellular response to leukemia inhibitory factor" 218885 218885 'Oxnad1' mRNA 420.85 497.35 418.75 11.44 13.46 12.12 7.77 5.99 7.95 12.34 7.236666667 327.26 247.67 322.67 445.65 299.2 8.66E-05 -0.586970626 GO:0005739///mitochondrion GO:0016491///oxidoreductase activity 218914 218914 'Wapl' mRNA 1056 949 1206 8.83 7.81 10.69 10.07 9.47 10.04 9.11 9.86 1388 1275 1340 1070.333333 1334.333333 0.009827164 0.299915744 GO:0000785///chromatin+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0009636///response to toxic substance+++GO:0035562///negative regulation of chromatin binding+++GO:0045875///negative regulation of sister chromatid cohesion+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051301///cell division+++GO:0051983///regulation of chromosome segregation+++GO:0060623///regulation of chromosome condensation+++GO:0071168///protein localization to chromatin+++GO:0071922///regulation of cohesin loading 21892 21892 'Tll1' mRNA 436 495 291 4.38 4.91 3.01 0.34 0.32 0.24 4.1 0.3 38 36 29 407.3333333 34.33333333 1.51E-52 -3.5707115 GO:0005576///extracellular region GO:0004222///metalloendopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation 21894 21894 'Tln1' mRNA 2427 2390 2143 15.09 14.6 14.12 23.53 23.69 24.68 14.60333333 23.96666667 4352 4303 4448 2320 4367.666667 7.36E-52 0.902911477 04015///Rap1 signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++05131///Shigellosis+++05166///Human T-cell leukemia virus 1 infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0001786///phosphatidylserine binding+++GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0017166///vinculin binding+++GO:0030274///LIM domain binding+++GO:0030276///clathrin binding+++GO:0035091///phosphatidylinositol binding+++GO:0051015///actin filament binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007044///cell-substrate junction assembly+++GO:0007155///cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0030866///cortical actin cytoskeleton organization+++GO:0033622///integrin activation+++GO:0098609///cell-cell adhesion 218952 218952 'Fermt2' mRNA 1489 1601 1558 25.06 26.52 27.79 27.06 27 25.4 26.45666667 26.48666667 1850 1804 1682 1549.333333 1778.666667 0.02836591 0.186376111 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0031674///I band+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0046332///SMAD binding+++GO:0051015///actin filament binding" "GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016055///Wnt signaling pathway+++GO:0022604///regulation of cell morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0033622///integrin activation+++GO:0033625///positive regulation of integrin activation+++GO:0034334///adherens junction maintenance+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035505///positive regulation of myosin light chain kinase activity+++GO:0043116///negative regulation of vascular permeability+++GO:0043547///positive regulation of GTPase activity+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048041///focal adhesion assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060173///limb development+++GO:0060548///negative regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072657///protein localization to membrane+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902414///protein localization to cell junction+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:1903691///positive regulation of wound healing, spreading of epidermal cells" 21897 21897 'Tlr1' mRNA 52.47 59.94 71.85 0.99 1.21 1.48 9.06 7.62 7.74 1.226666667 8.14 547.66 453.22 459.57 61.42 486.8166667 4.92E-59 2.986494787 04620///Toll-like receptor signaling pathway+++05152///Tuberculosis GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0035354///Toll-like receptor 1-Toll-like receptor 2 protein complex+++GO:0045121///membrane raft+++GO:0045335///phagocytic vesicle "GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0016787///hydrolase activity+++GO:0035663///Toll-like receptor 2 binding+++GO:0038023///signaling receptor activity+++GO:0042497///triacyl lipopeptide binding+++GO:0042802///identical protein binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating+++GO:0071723///lipopeptide binding" GO:0001774///microglial cell activation+++GO:0001775///cell activation+++GO:0001817///regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0032493///response to bacterial lipoprotein+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034130///toll-like receptor 1 signaling pathway+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0042116///macrophage activation+++GO:0042495///detection of triacyl bacterial lipopeptide+++GO:0045087///innate immune response+++GO:0071221///cellular response to bacterial lipopeptide+++GO:0071727///cellular response to triacyl bacterial lipopeptide 218973 218973 'Wdhd1' mRNA 42 48 37 0.54 0.63 0.5 1.58 1.57 1.61 0.556666667 1.586666667 145 141 142 42.33333333 142.6666667 2.79E-11 1.743979508 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043596///nuclear replication fork" GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0070063///RNA polymerase binding GO:0000278///mitotic cell cycle+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006396///RNA processing+++GO:0033044///regulation of chromosome organization+++GO:0070829///heterochromatin maintenance 218975 218975 'Mapk1ip1l' mRNA 1304 1333 1304 14.99 15.06 15.9 21.04 18.76 19.46 15.31666667 19.75333333 2106 1834 1889 1313.666667 1943 1.60E-12 0.551334817 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 218977 218977 'Dlgap5' mRNA 9 5 5 0.17 0.09 0.1 3.06 2.1 2.26 0.12 2.473333333 183.27 122 136 6.333333333 147.09 1.45E-25 4.523210146 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0034451///centriolar satellite GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007059///chromosome segregation+++GO:0007346///regulation of mitotic cell cycle+++GO:0023052///signaling+++GO:0051382///kinetochore assembly+++GO:0051642///centrosome localization 21898 21898 'Tlr4' mRNA 303 268 193 2.01 1.75 1.36 5.41 4.95 5.4 1.706666667 5.253333333 942 839 911 254.6666667 897.3333333 1.41E-43 1.810618981 04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0001726///ruffle+++GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0046696///lipopolysaccharide receptor complex+++GO:0048471///perinuclear region of cytoplasm "GO:0001530///lipopolysaccharide binding+++GO:0001875///lipopolysaccharide receptor activity+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0046982///protein heterodimerization activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0000187///activation of MAPK activity+++GO:0001774///microglial cell activation+++GO:0002218///activation of innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0002246///wound healing involved in inflammatory response+++GO:0002322///B cell proliferation involved in immune response+++GO:0002376///immune system process+++GO:0002537///nitric oxide production involved in inflammatory response+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0002758///innate immune response-activating signal transduction+++GO:0006691///leukotriene metabolic process+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007252///I-kappaB phosphorylation+++GO:0009617///response to bacterium+++GO:0010572///positive regulation of platelet activation+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0014002///astrocyte development+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030890///positive regulation of B cell proliferation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0032497///detection of lipopolysaccharide+++GO:0032609///interferon-gamma production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032707///negative regulation of interleukin-23 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042116///macrophage activation+++GO:0042742///defense response to bacterium+++GO:0043032///positive regulation of macrophage activation+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043388///positive regulation of DNA binding+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045087///innate immune response+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045471///response to ethanol+++GO:0045576///mast cell activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051930///regulation of sensory perception of pain+++GO:0060729///intestinal epithelial structure maintenance+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070430///positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0070542///response to fatty acid+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071260///cellular response to mechanical stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903974///positive regulation of cellular response to macrophage colony-stimulating factor stimulus+++GO:1904466///positive regulation of matrix metallopeptidase secretion+++GO:1904646///cellular response to amyloid-beta+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 218989 218989 'Tmem260' mRNA 772 877 484 8.2 9.93 5.4 3.28 4.28 4.01 7.843333333 3.856666667 372 458 424 711 418 4.87E-06 -0.764450876 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 21899 21899 'Tlr6' mRNA 54.53 57.06 43.15 1.01 0.85 0.67 3.69 3.87 3.87 0.843333333 3.81 259.34 244.78 254.43 51.58 252.85 8.54E-27 2.288713163 04145///Phagosome+++04620///Toll-like receptor signaling pathway+++05132///Salmonella infection+++05142///Chagas disease+++05152///Tuberculosis+++05417///Lipid and atherosclerosis GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft "GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0035663///Toll-like receptor 2 binding+++GO:0038023///signaling receptor activity+++GO:0042498///diacyl lipopeptide binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating+++GO:0071723///lipopeptide binding" GO:0001774///microglial cell activation+++GO:0001775///cell activation+++GO:0001817///regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0032493///response to bacterial lipoprotein+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0034150///toll-like receptor 6 signaling pathway+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0043032///positive regulation of macrophage activation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0046209///nitric oxide metabolic process+++GO:0050729///positive regulation of inflammatory response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071221///cellular response to bacterial lipopeptide+++GO:0071726///cellular response to diacyl bacterial lipopeptide+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904646///cellular response to amyloid-beta 219022 219022 'Ttc5' mRNA 1403.23 1430.54 1407.04 41.3 41.6 44.09 34.79 35.15 34.75 42.33 34.89666667 1344.85 1331.01 1308.12 1413.603333 1327.993333 0.262725077 -0.102495986 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II 219024 219024 'Pip4p1' mRNA 1047 1156 302 38.31 41.83 11.76 13.76 16.8 20.5 30.63333333 17.02 423 516 621 835 520 0.317756176 -0.666661412 04070///Phosphatidylinositol signaling system GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane "GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0034597///phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity" GO:0006991///response to sterol depletion+++GO:0008203///cholesterol metabolic process+++GO:0032418///lysosome localization+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0070070///proton-transporting V-type ATPase complex assembly+++GO:1904263///positive regulation of TORC1 signaling 219026 219026 'Eddm3b' mRNA 15 12 9 0.64 0.51 0.41 0.07 0 0 0.52 0.023333333 2 0 0 12 0.666666667 0.004125881 -4.183357649 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 219033 219033 'Ang4' mRNA 0 2 4 0 0.2 0.44 0.92 0.97 0.97 0.213333333 0.953333333 10.16 10.5 10.41 2 10.35666667 0.057450404 2.291328562 05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0015629///actin cytoskeleton+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle GO:0003676///nucleic acid binding+++GO:0003779///actin binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005102///signaling receptor binding+++GO:0005507///copper ion binding+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001878///response to yeast+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006401///RNA catabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0007202///activation of phospholipase C activity+++GO:0008284///positive regulation of cell proliferation+++GO:0009303///rRNA transcription+++GO:0009617///response to bacterium+++GO:0009725///response to hormone+++GO:0016477///cell migration+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0032148///activation of protein kinase B activity+++GO:0032431///activation of phospholipase A2 activity+++GO:0042327///positive regulation of phosphorylation+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 21906 21906 'Otop1' mRNA 1522 1617 1305 26.45 27.65 24.06 11.1 12.63 11.07 26.05333333 11.6 735 817 710 1481.333333 754 2.05E-25 -0.981542745 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015252///proton channel activity GO:0006811///ion transport+++GO:0009590///detection of gravity+++GO:0031214///biomineral tissue development+++GO:0032869///cellular response to insulin stimulus+++GO:0042472///inner ear morphogenesis+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:1902600///proton transmembrane transport 21907 21907 'Nr2e1' mRNA 0 3 1 0 0.03 0.01 0.02 0 0 0.013333333 0.006666667 2 0 0 1.333333333 0.666666667 0.784273251 -1.021665453 04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001662///behavioral fear response+++GO:0002118///aggressive behavior+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007601///visual perception+++GO:0008284///positive regulation of cell proliferation+++GO:0008347///glial cell migration+++GO:0021542///dentate gyrus development+++GO:0021764///amygdala development+++GO:0021772///olfactory bulb development+++GO:0021819///layer formation in cerebral cortex+++GO:0021872///forebrain generation of neurons+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021960///anterior commissure morphogenesis+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030522///intracellular receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035176///social behavior+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0045165///cell fate commitment+++GO:0045665///negative regulation of neuron differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048856///anatomical structure development+++GO:0051128///regulation of cellular component organization+++GO:0060041///retina development in camera-type eye+++GO:0060164///regulation of timing of neuron differentiation+++GO:0060291///long-term synaptic potentiation+++GO:0090049///regulation of cell migration involved in sprouting angiogenesis+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000648///positive regulation of stem cell proliferation" 219072 219072 'Haus4' mRNA 185 236 233 6.77 8.45 9.07 9.59 10.72 11.39 8.096666667 10.56666667 300 330 343 218 324.3333333 0.001251318 0.560400892 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function+++GO:0051011///microtubule minus-end binding GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 219094 219094 'Khnyn' mRNA 1259.2 1269.94 1360.59 11.33 11.23 12.98 7.56 7.86 6.96 11.84666667 7.46 967.51 982.69 862.45 1296.576667 937.55 1.13E-06 -0.482282305 GO:0005634///nucleus+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004521///endoribonuclease activity "GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 219103 219103 'Cenpj' mRNA 129 126 136 1.43 1.35 1.64 1.85 1.38 1.97 1.473333333 1.733333333 194 141 192 130.3333333 175.6666667 0.070968789 0.414861406 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0036064///ciliary basal body GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding "GO:0007099///centriole replication+++GO:0007224///smoothened signaling pathway+++GO:0030954///astral microtubule nucleation+++GO:0044458///motile cilium assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046599///regulation of centriole replication+++GO:0046785///microtubule polymerization+++GO:0051298///centrosome duplication+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0061511///centriole elongation+++GO:0098534///centriole assembly+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1903724///positive regulation of centriole elongation+++GO:1904951///positive regulation of establishment of protein localization+++GO:1905515///non-motile cilium assembly" 219105 219105 'Zmym5' mRNA 1191.15 1247.9 1108.75 11.52 11.98 11.46 7.52 8.12 7.82 11.65333333 7.82 918.22 953.26 913.05 1182.6 928.1766667 3.96E-05 -0.35889862 GO:0005634///nucleus GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II 219114 219114 'Ska3' mRNA 6 8 15 0.15 0.2 0.41 2.09 2.55 1.65 0.253333333 2.096666667 96 115 74 9.666666667 95 6.98E-14 3.277536215 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0072686///mitotic spindle" GO:0003674///molecular_function GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0051301///cell division 21912 21912 'Tspan7' mRNA 5459 5858 5187 177.04 187.29 178.66 121.16 123.02 118.99 180.9966667 121.0566667 4292 4246 4071 5501.333333 4203 2.19E-12 -0.398723962 05202///Transcriptional misregulation in cancer GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 219131 219131 'Phf11a' mRNA 21.08 28.65 25.12 1.05 1.32 1.23 8.37 9.04 9.48 1.2 8.963333333 213.53 225.08 230.54 24.95 223.05 1.52E-33 3.163704777 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0050776///regulation of immune response 219132 219132 'Phf11d' mRNA 150.07 144.19 112.28 3.09 2.93 2.46 11.58 10.25 10.89 2.826666667 10.90666667 646.15 558.32 588.27 135.5133333 597.58 1.15E-49 2.132861371 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 219134 219134 'Shisa2' mRNA 423 413 359 7.36 7.07 6.63 3.31 2.82 2.78 7.02 2.97 219 182 178 398.3333333 193 2.06E-12 -1.05609982 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007275///multicellular organism development+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway 219135 219135 'Mtmr6' mRNA 1583 1748 1561 22.3 24.15 23.31 25.44 22.54 24.25 23.25333333 24.07666667 2077 1799 1919 1630.666667 1931.666667 0.003608661 0.232488473 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity+++GO:0052866///phosphatidylinositol phosphate phosphatase activity+++GO:0106018///phosphatidylinositol-3,5-bisphosphate phosphatase activity" GO:0006629///lipid metabolic process+++GO:0006897///endocytosis+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation 219140 219140 'Spata13' mRNA 2864.87 3079.74 2574 20.48 21.63 19.49 10.76 9.12 9.66 20.53333333 9.846666667 1745.67 1447 1517.35 2839.536667 1570.006667 6.49E-30 -0.86549637 04810///Regulation of actin cytoskeleton GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding GO:0016477///cell migration+++GO:0030032///lamellipodium assembly+++GO:0030334///regulation of cell migration+++GO:0035556///intracellular signal transduction+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 219144 219144 'Arl11' mRNA 24 20 15 0.96 0.75 0.64 20.55 22.63 21.25 0.783333333 21.47666667 591 635 591 19.66666667 605.6666667 1.14E-100 4.936080378 GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport 219148 219148 'Fam167a' mRNA 121 116 64 1.58 1.47 0.87 0.19 0.51 0.33 1.306666667 0.343333333 17 44 27 100.3333333 29.33333333 5.39E-06 -1.767445705 GO:0008150///biological_process 219149 219149 'Xkr6' mRNA 466 400 360 1.29 0.83 0.66 0.11 0.2 0.09 0.926666667 0.133333333 73 78 64 408.6666667 71.66666667 1.62E-43 -2.520276282 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0043652///engulfment of apoptotic cell+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:1902742///apoptotic process involved in development 21915 21915 'Dtymk' mRNA 675 705 675 49.74 51.89 53.32 59.72 65.55 55.26 51.65 60.17666667 869 904 765 685 846 0.007859128 0.292909401 00240///Pyrimidine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0004798///thymidylate kinase activity+++GO:0005524///ATP binding+++GO:0009041///uridylate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006227///dUDP biosynthetic process+++GO:0006233///dTDP biosynthetic process+++GO:0006235///dTTP biosynthetic process+++GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0043627///response to estrogen+++GO:0045445///myoblast differentiation+++GO:0046686///response to cadmium ion+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0071363///cellular response to growth factor stimulus 219150 219150 'Hmbox1' mRNA 659 630 534 6.61 6.93 5.98 5.16 4.69 4.64 6.506666667 4.83 547 453 526 607.6666667 508.6666667 0.034652434 -0.266390965 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0016605///PML body" GO:0003677///DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035563///positive regulation of chromatin binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051972///regulation of telomerase activity+++GO:0051973///positive regulation of telomerase activity" 219151 219151 'Scara3' mRNA 2255 2332 2447 36.24 36.84 41.7 48.47 45.91 47.52 38.26 47.3 3471 3213 3302 2344.666667 3328.666667 3.04E-11 0.490871038 GO:0000139///Golgi membrane+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent GO:0030198///extracellular matrix organization 219158 219158 'Ccar2' mRNA 1201 1143 1135 17.53 16.41 17.56 11.91 12.07 11.98 17.16666667 11.98666667 937 930 916 1159.666667 927.6666667 1.67E-04 -0.333931608 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0044609///DBIRD complex GO:0000993///RNA polymerase II complex binding+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0009411///response to UV+++GO:0016055///Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0031647///regulation of protein stability+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090311///regulation of protein deacetylation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000003///positive regulation of DNA damage checkpoint" 21916 21916 'Tmod1' mRNA 23335.16 23448.45 22310.85 448.51 443.62 455.2 140.94 137.88 139.96 449.11 139.5933333 8437.72 8057.88 8105.07 23031.48667 8200.223333 6.39E-235 -1.50180921 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0005884///actin filament+++GO:0008180///COP9 signalosome+++GO:0016020///membrane+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0030863///cortical cytoskeleton GO:0003779///actin binding+++GO:0005523///tropomyosin binding+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0008344///adult locomotory behavior+++GO:0030239///myofibril assembly+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0051694///pointed-end actin filament capping+++GO:0070307///lens fiber cell development 21917 21917 'Tmpo' mRNA 566 600 492 8.91 9.22 8.19 9.48 8.98 10.54 8.773333333 9.666666667 687 638 741 552.6666667 688.6666667 0.008099916 0.308466369 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated" 219170 219170 'Fam216b' mRNA 81 95 110 2.04 2.35 2.93 0.11 0.02 0.09 2.44 0.073333333 5 1 4 95.33333333 3.333333333 2.50E-17 -4.857906862 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 219181 219181 'Akap11' mRNA 1468 1516 1174 8.27 8.34 7 6.26 5.9 6.38 7.87 6.18 1281 1185 1270 1386 1245.333333 0.097363746 -0.161925542 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019207///kinase regulator activity+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034237///protein kinase A regulatory subunit binding GO:0001934///positive regulation of protein phosphorylation+++GO:0003091///renal water homeostasis+++GO:0030866///cortical actin cytoskeleton organization+++GO:0034613///cellular protein localization+++GO:0036010///protein localization to endosome+++GO:0050790///regulation of catalytic activity+++GO:1903142///positive regulation of establishment of endothelial barrier 219189 219189 'Vwa8' mRNA 1060 1075 995 8.76 8.65 8.54 6.29 6.15 5.65 8.65 6.03 749 729 693 1043.333333 723.6666667 2.62E-09 -0.538916939 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0008150///biological_process 21922 21922 'Clec3b' mRNA 13 13 11 0.84 0.83 0.75 1.01 0.69 0.82 0.806666667 0.84 18 12 14 12.33333333 14.66666667 0.791470652 0.237740753 GO:0001652///granular component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0030246///carbohydrate binding+++GO:0036143///kringle domain binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0010756///positive regulation of plasminogen activation+++GO:0030282///bone mineralization+++GO:0071310///cellular response to organic substance+++GO:0071560///cellular response to transforming growth factor beta stimulus 219228 219228 'Pcdh17' mRNA 107 126 106 0.56 0.65 0.57 0.32 0.31 0.31 0.593333333 0.313333333 72 67 66 113 68.33333333 0.005552885 -0.736127113 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0030534///adult behavior+++GO:0050805///negative regulation of synaptic transmission+++GO:0099560///synaptic membrane adhesion+++GO:1904071///presynaptic active zone assembly+++GO:2000807///regulation of synaptic vesicle clustering 21923 21923 'Tnc' mRNA 1147 1153 1235 10.44 10.2 11.86 3.69 3.48 3.68 10.83333333 3.616666667 531 461 492 1178.333333 494.6666667 6.92E-35 -1.267531358 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0098966///perisynaptic extracellular matrix GO:0001968///fibronectin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0045545///syndecan binding GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0007528///neuromuscular junction development+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0010628///positive regulation of gene expression+++GO:0014012///peripheral nervous system axon regeneration+++GO:0031175///neuron projection development+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045471///response to ethanol+++GO:0060447///bud outgrowth involved in lung branching+++GO:0060739///mesenchymal-epithelial cell signaling involved in prostate gland development+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0071300///cellular response to retinoic acid+++GO:0071305///cellular response to vitamin D+++GO:0071774///response to fibroblast growth factor+++GO:0071799///cellular response to prostaglandin D stimulus 21924 21924 'Tnnc1' mRNA 6 8 3 0.59 0.78 0.31 1.8 2.11 1.78 0.56 1.896666667 21 24 20 5.666666667 21.66666667 0.008131098 1.935249022 04020///Calcium signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005861///troponin complex+++GO:0043292///contractile fiber+++GO:1990584///cardiac Troponin complex GO:0005509///calcium ion binding+++GO:0031013///troponin I binding+++GO:0031014///troponin T binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding GO:0002086///diaphragm contraction+++GO:0003009///skeletal muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0010038///response to metal ion+++GO:0014883///transition between fast and slow fiber+++GO:0032972///regulation of muscle filament sliding speed+++GO:0043462///regulation of ATPase activity+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction 219249 219249 'Tdrd3' mRNA 837.16 816.89 892.56 10.21 8.83 12.1 6.87 6.32 6.57 10.38 6.586666667 726.58 691.89 715.55 848.87 711.34 0.013980507 -0.270058299 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0035064///methylated histone binding "GO:0006325///chromatin organization+++GO:0006397///mRNA processing+++GO:0045893///positive regulation of transcription, DNA-templated" 21925 21925 'Tnnc2' mRNA 5 10 4 0.52 1.03 0.44 0.54 0.74 0.66 0.663333333 0.646666667 6 8 7 6.333333333 7 0.90356188 0.147375331 04020///Calcium signaling pathway GO:0005861///troponin complex GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0006937///regulation of muscle contraction 219257 219257 'Pcdh20' mRNA 8833 8980 9466 97.79 97.67 110.61 8.58 8.01 7.49 102.0233333 8.026666667 899 818 757 9093 824.6666667 0 -3.478161604 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 21926 21926 'Tnf' mRNA 8 9 13 0.29 0.32 0.5 5.86 5.07 5.2 0.37 5.376666667 191 161 164 10 172 1.98E-30 4.088528937 01523///Antifolate resistance+++04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04064///NF-kappa B signaling pathway+++04071///Sphingolipid signaling pathway+++04150///mTOR signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04350///TGF-beta signaling pathway+++04380///Osteoclast differentiation+++04612///Antigen processing and presentation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04640///Hematopoietic cell lineage+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++04940///Type I diabetes mellitus+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05310///Asthma+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0001891///phagocytic cup+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0045121///membrane raft+++GO:0055037///recycling endosome GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0002020///protease binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000185///activation of MAPKKK activity+++GO:0000187///activation of MAPK activity+++GO:0001774///microglial cell activation+++GO:0001819///positive regulation of cytokine production+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002269///leukocyte activation involved in inflammatory response+++GO:0002439///chronic inflammatory response to antigenic stimulus+++GO:0002637///regulation of immunoglobulin production+++GO:0002719///negative regulation of cytokine production involved in immune response+++GO:0002876///positive regulation of chronic inflammatory response to antigenic stimulus+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006006///glucose metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009615///response to virus+++GO:0009887///animal organ morphogenesis+++GO:0010033///response to organic substance+++GO:0010573///vascular endothelial growth factor production+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0030198///extracellular matrix organization+++GO:0030316///osteoclast differentiation+++GO:0030730///sequestering of triglyceride+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031622///positive regulation of fever generation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0042127///regulation of cell proliferation+++GO:0042742///defense response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0043068///positive regulation of programmed cell death+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043242///negative regulation of protein complex disassembly+++GO:0043243///positive regulation of protein complex disassembly+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043491///protein kinase B signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045071///negative regulation of viral genome replication+++GO:0045123///cellular extravasation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045785///positive regulation of cell adhesion+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045994///positive regulation of translational initiation by iron+++GO:0046325///negative regulation of glucose import+++GO:0046330///positive regulation of JNK cascade+++GO:0048566///embryonic digestive tract development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050708///regulation of protein secretion+++GO:0050727///regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050796///regulation of insulin secretion+++GO:0050806///positive regulation of synaptic transmission+++GO:0050807///regulation of synapse organization+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050900///leukocyte migration+++GO:0050901///leukocyte tethering or rolling+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051173///positive regulation of nitrogen compound metabolic process+++GO:0051222///positive regulation of protein transport+++GO:0051384///response to glucocorticoid+++GO:0051798///positive regulation of hair follicle development+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060557///positive regulation of vitamin D biosynthetic process+++GO:0060559///positive regulation of calcidiol 1-monooxygenase activity+++GO:0060664///epithelial cell proliferation involved in salivary gland morphogenesis+++GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0061044///negative regulation of vascular wound healing+++GO:0061048///negative regulation of branching involved in lung morphogenesis+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071316///cellular response to nicotine+++GO:0071407///cellular response to organic cyclic compound+++GO:0071803///positive regulation of podosome assembly+++GO:0072577///endothelial cell apoptotic process+++GO:0072659///protein localization to plasma membrane+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097527///necroptotic signaling pathway+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901647///positive regulation of synoviocyte proliferation+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1903347///negative regulation of bicellular tight junction assembly+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:1904999///positive regulation of leukocyte adhesion to arterial endothelial cell+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000272///negative regulation of signaling receptor activity+++GO:2000334///positive regulation of blood microparticle formation+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000351///regulation of endothelial cell apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand" 21927 21927 'Tnfaip1' mRNA 3069 3383 3345 44.94 48.72 51.97 38.84 38.9 39.51 48.54333333 39.08333333 3051 2988 3006 3265.666667 3015 0.103788471 -0.128535577 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0030332///cyclin binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0006955///immune response+++GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043149///stress fiber assembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045740///positive regulation of DNA replication+++GO:0051260///protein homooligomerization 21928 21928 'Tnfaip2' mRNA 1705 2041 1434 26.27 31.06 23.47 6.77 7.2 7.32 26.93333333 7.096666667 510 524 532 1726.666667 522 3.50E-61 -1.731169185 GO:0000145///exocyst GO:0000149///SNARE binding GO:0001525///angiogenesis+++GO:0006887///exocytosis+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0051601///exocyst localization 21929 21929 'Tnfaip3' mRNA 171 147 165 2.08 1.76 2.14 5.28 4.09 4.63 1.993333333 4.666666667 499 378 422 161 433 1.81E-18 1.411700777 04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05162///Measles+++05169///Epstein-Barr virus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome GO:0002020///protease binding+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0001922///B-1 B cell homeostasis+++GO:0002237///response to molecule of bacterial origin+++GO:0002315///marginal zone B cell differentiation+++GO:0002632///negative regulation of granuloma formation+++GO:0002634///regulation of germinal center formation+++GO:0002637///regulation of immunoglobulin production+++GO:0002677///negative regulation of chronic inflammatory response+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007010///cytoskeleton organization+++GO:0008152///metabolic process+++GO:0009611///response to wounding+++GO:0010507///negative regulation of autophagy+++GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0016579///protein deubiquitination+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032495///response to muramyl dipeptide+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0034140///negative regulation of toll-like receptor 3 signaling pathway+++GO:0034148///negative regulation of toll-like receptor 5 signaling pathway+++GO:0035523///protein K29-linked deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045088///regulation of innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045824///negative regulation of innate immune response+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0050869///negative regulation of B cell activation+++GO:0060548///negative regulation of cell death+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070429///negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070433///negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0070536///protein K63-linked deubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:0072573///tolerance induction to lipopolysaccharide+++GO:0072666///establishment of protein localization to vacuole+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1990168///protein K33-linked deubiquitination+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000349///negative regulation of CD40 signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process 21930 21930 'Tnfaip6' mRNA 71.01 64.23 64 2.6 2.32 2.48 3.91 3.88 3.52 2.466666667 3.77 123 119 107 66.41333333 116.3333333 0.00247611 0.798632519 GO:0005615///extracellular space GO:0005540///hyaluronic acid binding GO:0007155///cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:0030728///ovulation+++GO:0050728///negative regulation of inflammatory response 21933 21933 'Tnfrsf10b' mRNA 178.47 173.53 148.48 3.09 2.97 2.73 5.65 4.52 5.49 2.93 5.22 375.05 293.7 353.65 166.8266667 340.8 5.85E-10 1.021954836 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04115///p53 signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04650///Natural killer cell mediated cytotoxicity+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05164///Influenza A+++05417///Lipid and atherosclerosis GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0008134///transcription factor binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0036463///TRAIL receptor activity+++GO:0042802///identical protein binding+++GO:0045569///TRAIL binding GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0097191///extrinsic apoptotic signaling pathway 21934 21934 'Tnfrsf11a' mRNA 69.87 75 72 0.71 0.77 0.77 4.46 3 5.18 0.75 4.213333333 489 335 557 72.29 460.3333333 6.59E-39 2.662612476 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04917///Prolactin signaling pathway+++05323///Rheumatoid arthritis GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0002250///adaptive immune response+++GO:0007275///multicellular organism development+++GO:0009314///response to radiation+++GO:0030316///osteoclast differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034097///response to cytokine+++GO:0034612///response to tumor necrosis factor+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045780///positive regulation of bone resorption+++GO:0048535///lymph node development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060086///circadian temperature homeostasis+++GO:0060749///mammary gland alveolus development+++GO:0070555///response to interleukin-1+++GO:0071812///positive regulation of fever generation by positive regulation of prostaglandin secretion+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0071848///positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling+++GO:0072674///multinuclear osteoclast differentiation 21935 21935 'Tnfrsf17' mRNA 0 1 5 0 0.08 0.43 0.58 0.67 0.3 0.17 0.516666667 8 9 4 2 7 0.230883957 1.759427184 04060///Cytokine-cytokine receptor interaction+++04672///Intestinal immune network for IgA production GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0002250///adaptive immune response+++GO:0002260///lymphocyte homeostasis+++GO:0002376///immune system process+++GO:0033209///tumor necrosis factor-mediated signaling pathway 21936 21936 'Tnfrsf18' mRNA 34 28 28 2.26 1.71 1.89 4.57 4.41 5.74 1.953333333 4.906666667 85 80 100 30 88.33333333 3.11E-06 1.54728921 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding GO:0002687///positive regulation of leukocyte migration+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043066///negative regulation of apoptotic process+++GO:0045785///positive regulation of cell adhesion 21937 21937 'Tnfrsf1a' mRNA 1904 1926 1744 49.91 49.73 48.5 124.68 123.99 127.58 49.38 125.4166667 5469 5310 5417 1858 5398.666667 1.86E-160 1.528368868 04010///MAPK signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04064///NF-kappa B signaling pathway+++04071///Sphingolipid signaling pathway+++04150///mTOR signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04380///Osteoclast differentiation+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0002020///protease binding+++GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043120///tumor necrosis factor binding+++GO:0044877///protein-containing complex binding GO:0003176///aortic valve development+++GO:0003177///pulmonary valve development+++GO:0003332///negative regulation of extracellular matrix constituent secretion+++GO:0006693///prostaglandin metabolic process+++GO:0006915///apoptotic process+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042742///defense response to bacterium+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050728///negative regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0071260///cellular response to mechanical stimulus+++GO:0072659///protein localization to plasma membrane+++GO:1902339///positive regulation of apoptotic process involved in morphogenesis+++GO:1903140///regulation of establishment of endothelial barrier 21938 21938 'Tnfrsf1b' mRNA 242 242 272 2.89 2.89 3.8 16.57 15.91 15.15 3.193333333 15.87666667 1635 1475 1376 252 1495.333333 6.85E-119 2.55390787 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043196///varicosity+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043120///tumor necrosis factor binding GO:0002718///regulation of cytokine production involved in immune response+++GO:0002724///regulation of T cell cytokine production+++GO:0003176///aortic valve development+++GO:0003177///pulmonary valve development+++GO:0003332///negative regulation of extracellular matrix constituent secretion+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007568///aging+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0031641///regulation of myelination+++GO:0031643///positive regulation of myelination+++GO:0032496///response to lipopolysaccharide+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042129///regulation of T cell proliferation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050779///RNA destabilization+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0060548///negative regulation of cell death+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0150077///regulation of neuroinflammatory response+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1902339///positive regulation of apoptotic process involved in morphogenesis+++GO:2001141///regulation of RNA biosynthetic process 21939 21939 'Cd40' mRNA 15 34 26 0.52 1.16 0.96 8.2 6.77 5.4 0.88 6.79 272 217 173 25 220.6666667 3.50E-26 3.127896561 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04514///Cell adhesion molecules+++04620///Toll-like receptor signaling pathway+++04672///Intestinal immune network for IgA production+++05144///Malaria+++05145///Toxoplasmosis+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05202///Transcriptional misregulation in cancer+++05310///Asthma+++05320///Autoimmune thyroid disease+++05322///Systemic lupus erythematosus+++05330///Allograft rejection+++05340///Primary immunodeficiency+++05416///Viral myocarditis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035631///CD40 receptor complex+++GO:0043025///neuronal cell body+++GO:0043196///varicosity+++GO:0043231///intracellular membrane-bounded organelle GO:0003823///antigen binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0038023///signaling receptor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0002377///immunoglobulin production+++GO:0002637///regulation of immunoglobulin production+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0006874///cellular calcium ion homeostasis+++GO:0006954///inflammatory response+++GO:0009617///response to bacterium+++GO:0019724///B cell mediated immunity+++GO:0023035///CD40 signaling pathway+++GO:0030890///positive regulation of B cell proliferation+++GO:0031667///response to nutrient levels+++GO:0032735///positive regulation of interleukin-12 production+++GO:0033590///response to cobalamin+++GO:0034341///response to interferon-gamma+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0036018///cellular response to erythropoietin+++GO:0042113///B cell activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042832///defense response to protozoan+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043491///protein kinase B signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0050776///regulation of immune response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090037///positive regulation of protein kinase C signaling+++GO:1901652///response to peptide+++GO:2000353///positive regulation of endothelial cell apoptotic process 21940 21940 'Cd27' mRNA 48 33 31 1.8 1.23 1.29 1.97 0.92 1.46 1.44 1.45 58 27 40 37.33333333 41.66666667 0.808645921 0.144261901 04060///Cytokine-cytokine receptor interaction GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0002639///positive regulation of immunoglobulin production+++GO:0006915///apoptotic process+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042100///B cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045471///response to ethanol+++GO:0045579///positive regulation of B cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway 21941 21941 'Tnfrsf8' mRNA 4 3 2 0.06 0.05 0.03 0.19 0.31 0.3 0.046666667 0.266666667 14 22 21 3 19 0.001934876 2.660847451 04060///Cytokine-cytokine receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity GO:0007165///signal transduction+++GO:0032759///positive regulation of TRAIL production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0043065///positive regulation of apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 21942 21942 'Tnfrsf9' mRNA 4 9 13 0.11 0.25 0.38 1.16 0.61 0.64 0.246666667 0.803333333 49 25 25 8.666666667 33 0.002944059 1.898858215 04060///Cytokine-cytokine receptor interaction GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019955///cytokine binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0042127///regulation of cell proliferation 21944 21944 'Tnfsf12' mRNA 479.64 424.85 314.15 16.45 14.36 11.43 11.59 11.51 13.33 14.08 12.14333333 388.32 376.48 432.45 406.2133333 399.0833333 0.877853303 -0.030159578 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0048018///receptor ligand activity GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 21945 21945 'Dedd' mRNA 1198.86 1206.84 1088.06 19.45 19.22 19.03 15.29 15.07 17.4 19.23333333 15.92 990.28 953.5 1044.09 1164.586667 995.9566667 0.008687918 -0.235658793 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0042177///negative regulation of protein catabolic process+++GO:0042981///regulation of apoptotic process+++GO:0046697///decidualization+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I 21946 21946 'Pglyrp1' mRNA 74 65 72 7.85 6.85 8.11 14.21 12.6 10.78 7.603333333 12.53 153 132 112 70.33333333 132.3333333 5.31E-04 0.897092287 04624///Toll and Imd signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005125///cytokine activity+++GO:0008270///zinc ion binding+++GO:0008745///N-acetylmuramoyl-L-alanine amidase activity+++GO:0016019///peptidoglycan receptor activity+++GO:0042834///peptidoglycan binding GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0009253///peptidoglycan catabolic process+++GO:0009617///response to bacterium+++GO:0016045///detection of bacterium+++GO:0031640///killing of cells of other organism+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032827///negative regulation of natural killer cell differentiation involved in immune response+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050728///negative regulation of inflammatory response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051701///interaction with host+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 21948 21948 'Cd70' mRNA 1 0 1 0.08 0 0.08 0.28 0.07 0 0.053333333 0.116666667 4 1 0 0.666666667 1.666666667 0.691544474 1.275083481 04060///Cytokine-cytokine receptor interaction GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002020///protease binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding GO:0002456///T cell mediated immunity+++GO:0006955///immune response+++GO:0019724///B cell mediated immunity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042100///B cell proliferation+++GO:0097191///extrinsic apoptotic signaling pathway 21949 21949 'Tnfsf8' mRNA 6 7 7 0.1 0.17 0.13 7.28 7.85 7.28 0.133333333 7.47 448 442 441 6.666666667 443.6666667 1.37E-63 6.045468439 04060///Cytokine-cytokine receptor interaction GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding "GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0043374///CD8-positive, alpha-beta T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050830///defense response to Gram-positive bacterium" 21950 21950 'Tnfsf9' mRNA 53 54 44 3.08 2.99 2.61 6.65 5.25 5.2 2.893333333 5.7 150 116 112 50.33333333 126 1.55E-06 1.312636019 04060///Cytokine-cytokine receptor interaction GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0032813///tumor necrosis factor receptor superfamily binding GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045585///positive regulation of cytotoxic T cell differentiation 21951 21951 'Tnks' mRNA 283 285 277 2.32 2.3 2.41 2.38 2.02 2.12 2.343333333 2.173333333 333 276 288 281.6666667 299 0.722401076 0.072852488 "GO:0000139///Golgi membrane+++GO:0000781///chromosome, telomeric region+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031965///nuclear membrane+++GO:0097431///mitotic spindle pole" "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0000209///protein polyubiquitination+++GO:0006471///protein ADP-ribosylation+++GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031670///cellular response to nutrient+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051028///mRNA transport+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0051973///positive regulation of telomerase activity+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904355///positive regulation of telomere capping+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1904743///negative regulation of telomeric DNA binding+++GO:1904908///negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric" 21952 21952 'Tnni1' mRNA 43 58 43 2.44 3.14 2.72 3.09 2.89 3.86 2.766666667 3.28 62 59 74 48 65 0.252576668 0.429180602 GO:0005861///troponin complex GO:0003779///actin binding+++GO:0046872///metal ion binding GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0014883///transition between fast and slow fiber+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction 21953 21953 'Tnni2' mRNA 5 2 5 0.49 0.19 0.52 2.39 2.1 2.47 0.4 2.32 28 24 28 4 26.66666667 1.79E-04 2.718801411 GO:0005634///nucleus+++GO:0005861///troponin complex GO:0003779///actin binding+++GO:0031014///troponin T binding+++GO:0046872///metal ion binding "GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060048///cardiac muscle contraction" 21954 21954 'Tnni3' mRNA 79.25 78.32 52.97 4.25 4.15 3.14 1.25 1.73 1.2 3.846666667 1.393333333 23 31.58 24.31 70.18 26.29666667 1.73E-04 -1.424124641 04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005861///troponin complex+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0043292///contractile fiber+++GO:0097512///cardiac myofibril+++GO:1990584///cardiac Troponin complex GO:0003779///actin binding+++GO:0019855///calcium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030172///troponin C binding+++GO:0031014///troponin T binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding GO:0001570///vasculogenesis+++GO:0001980///regulation of systemic arterial blood pressure by ischemic conditions+++GO:0003009///skeletal muscle contraction+++GO:0006874///cellular calcium ion homeostasis+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007507///heart development+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0032780///negative regulation of ATPase activity+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060047///heart contraction+++GO:0060048///cardiac muscle contraction 21955 21955 'Tnnt1' mRNA 61 68 51 3.11 3.54 2.69 1.51 1.33 1.84 3.113333333 1.56 32 26 34 60 30.66666667 0.010378961 -0.976507478 GO:0005861///troponin complex GO:0005523///tropomyosin binding+++GO:0031014///troponin T binding GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0014883///transition between fast and slow fiber+++GO:0031444///slow-twitch skeletal muscle fiber contraction+++GO:0045214///sarcomere organization+++GO:0045932///negative regulation of muscle contraction 21956 21956 'Tnnt2' mRNA 163 189 145 8.36 9.56 7.88 6.76 5.45 6.51 8.6 6.24 152 120 142 165.6666667 138 0.243279646 -0.273176537 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005861///troponin complex+++GO:0005865///striated muscle thin filament+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0097512///cardiac myofibril+++GO:1990584///cardiac Troponin complex "GO:0000146///microfilament motor activity+++GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005523///tropomyosin binding+++GO:0030172///troponin C binding+++GO:0030674///protein binding, bridging+++GO:0031013///troponin I binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding" GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0007507///heart development+++GO:0008016///regulation of heart contraction+++GO:0009617///response to bacterium+++GO:0030049///muscle filament sliding+++GO:0032780///negative regulation of ATPase activity+++GO:0032781///positive regulation of ATPase activity+++GO:0032972///regulation of muscle filament sliding speed+++GO:0045214///sarcomere organization+++GO:0051592///response to calcium ion+++GO:0051764///actin crosslink formation+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction 21957 21957 'Tnnt3' mRNA 57 66 70 3.45 3.88 4.41 0.15 0.7 0.34 3.913333333 0.396666667 3 13 6 64.33333333 7.333333333 1.11E-09 -3.142640671 GO:0005861///troponin complex GO:0003779///actin binding+++GO:0005523///tropomyosin binding+++GO:0030172///troponin C binding+++GO:0031013///troponin I binding+++GO:0048306///calcium-dependent protein binding GO:0003009///skeletal muscle contraction+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0006942///regulation of striated muscle contraction+++GO:0043462///regulation of ATPase activity+++GO:0045214///sarcomere organization+++GO:1903612///positive regulation of calcium-dependent ATPase activity 21958 21958 'Tnp1' mRNA 2 0 0 0.45 0 0 0 0 0 0.15 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0000786///nucleosome+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding "GO:0000012///single strand break repair+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006342///chromatin silencing+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007290///spermatid nucleus elongation+++GO:0010954///positive regulation of protein processing+++GO:0019953///sexual reproduction+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0045892///negative regulation of transcription, DNA-templated" 21959 21959 'Tnp2' mRNA 0 0 1 0 0 0.15 0 0.13 0 0.05 0.043333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0000786///nucleosome+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007339///binding of sperm to zona pellucida+++GO:0007340///acrosome reaction+++GO:0007341///penetration of zona pellucida+++GO:0010954///positive regulation of protein processing+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0035093///spermatogenesis, exchange of chromosomal proteins" 21960 21960 'Tnr' mRNA 141 141 139 0.54 0.44 0.52 0.05 0.05 0.1 0.5 0.066666667 14 15 28 140.3333333 19 9.81E-19 -2.895978366 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0045121///membrane raft+++GO:0062023///collagen-containing extracellular matrix+++GO:0072534///perineuronal net+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098966///perisynaptic extracellular matrix+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0046625///sphingolipid binding "GO:0007155///cell adhesion+++GO:0007158///neuron cell-cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0008306///associative learning+++GO:0010977///negative regulation of neuron projection development+++GO:0022029///telencephalon cell migration+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030517///negative regulation of axon extension+++GO:0035641///locomotory exploration behavior+++GO:0048692///negative regulation of axon extension involved in regeneration+++GO:0050767///regulation of neurogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050805///negative regulation of synaptic transmission+++GO:0050808///synapse organization+++GO:0050885///neuromuscular process controlling balance+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0060291///long-term synaptic potentiation" 21961 21961 'Tns1' mRNA 7929 7927 6774 43.06 42.22 39.38 37.26 34.13 35.18 41.55333333 35.52333333 7762 7033 7188 7543.333333 7327.666667 0.459731585 -0.051516038 GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction GO:0003779///actin binding GO:0007044///cell-substrate junction assembly+++GO:0010761///fibroblast migration+++GO:0035556///intracellular signal transduction 21968 21968 'Tom1' mRNA 2621 2909 2834 64.53 70.69 74.01 41.92 44.38 46.02 69.74333333 44.10666667 1939 2016 2081 2788 2012 6.08E-10 -0.482952204 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding+++GO:0030276///clathrin binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0015031///protein transport 21969 21969 'Top1' mRNA 1315 1405 1292 18.49 19.43 19.27 20.83 20.87 22.4 19.06333333 21.36666667 1705 1669 1776 1337.333333 1716.666667 6.82E-06 0.349187613 GO:0000228///nuclear chromosome+++GO:0000932///P-body+++GO:0001650///fibrillar center+++GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032993///protein-DNA complex+++GO:0043204///perikaryon GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003916///DNA topoisomerase activity+++GO:0003917///DNA topoisomerase type I activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016853///isomerase activity+++GO:0019904///protein domain specific binding+++GO:0031490///chromatin DNA binding+++GO:0044877///protein-containing complex binding+++GO:0097100///supercoiled DNA binding GO:0006260///DNA replication+++GO:0006265///DNA topological change+++GO:0006338///chromatin remodeling+++GO:0007059///chromosome segregation+++GO:0007623///circadian rhythm+++GO:0009303///rRNA transcription+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032922///circadian regulation of gene expression+++GO:0040016///embryonic cleavage+++GO:0042493///response to drug+++GO:0048511///rhythmic process 21973 21973 'Top2a' mRNA 13 22 10 0.13 0.22 0.11 7.41 7.18 7.12 0.153333333 7.236666667 835 790 777 15 800.6666667 6.91E-119 5.728797646 01524///Platinum drug resistance "GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0009330///DNA topoisomerase complex (ATP-hydrolyzing)+++GO:0032991///protein-containing complex+++GO:1990904///ribonucleoprotein complex" "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003916///DNA topoisomerase activity+++GO:0003918///DNA topoisomerase type II (ATP-hydrolyzing) activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008301///DNA binding, bending+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043130///ubiquitin binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0000712///resolution of meiotic recombination intermediates+++GO:0000819///sister chromatid segregation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006259///DNA metabolic process+++GO:0006265///DNA topological change+++GO:0006266///DNA ligation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007059///chromosome segregation+++GO:0007143///female meiotic nuclear division+++GO:0030261///chromosome condensation+++GO:0030263///apoptotic chromosome condensation+++GO:0040016///embryonic cleavage+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0045870///positive regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0051309///female meiosis chromosome separation+++GO:1905463///negative regulation of DNA duplex unwinding 21974 21974 'Top2b' mRNA 1410 1439 684 13.31 13.36 6.85 6.66 8.29 8.87 11.17333333 7.94 812 988 1048 1177.666667 949.3333333 0.457340331 -0.304176362 01524///Platinum drug resistance GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003916///DNA topoisomerase activity+++GO:0003918///DNA topoisomerase type II (ATP-hydrolyzing) activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding+++GO:0042826///histone deacetylase binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0000819///sister chromatid segregation+++GO:0001764///neuron migration+++GO:0006259///DNA metabolic process+++GO:0006265///DNA topological change+++GO:0007409///axonogenesis+++GO:0007569///cell aging+++GO:0030900///forebrain development+++GO:0045870///positive regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071318///cellular response to ATP+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 21975 21975 'Top3a' mRNA 252 290 299 2.4 2.71 3.05 2.46 2.29 2.38 2.72 2.376666667 295 267 279 280.3333333 280.3333333 0.945744261 -0.014822999 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016605///PML body GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003916///DNA topoisomerase activity+++GO:0003917///DNA topoisomerase type I activity+++GO:0008270///zinc ion binding+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0006265///DNA topological change+++GO:0032042///mitochondrial DNA metabolic process+++GO:0051304///chromosome separation 21976 21976 'Top3b' mRNA 1052 1065 1058 18.69 18.48 19.7 15.59 15.35 15.36 18.95666667 15.43333333 996 972 959 1058.333333 975.6666667 0.190589007 -0.129880605 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0000793///condensed chromosome+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003916///DNA topoisomerase activity+++GO:0003917///DNA topoisomerase type I activity+++GO:0016853///isomerase activity GO:0006265///DNA topological change+++GO:0007059///chromosome segregation 21981 21981 'Ppp1r13b' mRNA 666 687 500 8.23 8.35 6.57 4.3 4.43 4.94 7.716666667 4.556666667 402 404 445 617.6666667 417 1.22E-05 -0.572240098 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm GO:0002039///p53 binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0051059///NF-kappaB binding GO:0006915///apoptotic process+++GO:0045786///negative regulation of cell cycle+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1901216///positive regulation of neuron death 21982 21982 'Tmem165' mRNA 350 295 229 10.57 8.78 7.34 12.59 10.42 12.27 8.896666667 11.76 479 387 452 291.3333333 439.3333333 2.47E-04 0.585049998 GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005384///manganese ion transmembrane transporter activity+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006487///protein N-linked glycosylation+++GO:0006874///cellular calcium ion homeostasis+++GO:0032468///Golgi calcium ion homeostasis+++GO:0032472///Golgi calcium ion transport+++GO:0035751///regulation of lysosomal lumen pH+++GO:0070588///calcium ion transmembrane transport+++GO:0071421///manganese ion transmembrane transport 21983 21983 'Tpbg' mRNA 537 595 122 8.28 9.03 2.01 4.14 6.07 7.09 6.44 5.766666667 312 445 513 418 423.3333333 0.969519197 0.039192443 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043679///axon terminus "GO:0008285///negative regulation of cell proliferation+++GO:0008355///olfactory learning+++GO:0050921///positive regulation of chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051932///synaptic transmission, GABAergic+++GO:0051965///positive regulation of synapse assembly+++GO:0060326///cell chemotaxis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090497///mesenchymal cell migration+++GO:0140059///dendrite arborization" 21985 21985 'Tpd52' mRNA 2966 3117 2870 66.5 68.71 68.7 73.95 75.11 74.01 67.97 74.35666667 3771 3702 3614 2984.333333 3695.666667 8.62E-07 0.297276372 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0008284///positive regulation of cell proliferation+++GO:0030183///B cell differentiation 21987 21987 'Tpd52l1' mRNA 428 475 490 21.49 23.45 26.04 26.42 26.57 27.14 23.66 26.71 605 594 603 464.3333333 600.6666667 0.004205411 0.357536166 GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:2001235///positive regulation of apoptotic signaling pathway 21990 21990 'Tph1' mRNA 79 72 64 1.25 0.9 0.86 0.09 0.08 0.11 1.003333333 0.093333333 8 7 10 71.66666667 8.333333333 7.78E-12 -3.113721291 00380///Tryptophan metabolism+++00790///Folate biosynthesis+++04361///Axon regeneration+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0043005///neuron projection "GO:0004497///monooxygenase activity+++GO:0004510///tryptophan 5-monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016714///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen+++GO:0046872///metal ion binding" GO:0002576///platelet degranulation+++GO:0007623///circadian rhythm+++GO:0009072///aromatic amino acid family metabolic process+++GO:0030279///negative regulation of ossification+++GO:0035902///response to immobilization stress+++GO:0042427///serotonin biosynthetic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0046849///bone remodeling+++GO:0060749///mammary gland alveolus development+++GO:1900046///regulation of hemostasis 21991 21991 'Tpi1' mRNA 10347 10255 10009 417.55 408.22 428.51 439.13 427.38 440.94 418.0933333 435.8166667 12499 11869 12141 10203.66667 12169.66667 2.19E-06 0.241820019 00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism+++00562///Inositol phosphate metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004807///triose-phosphate isomerase activity+++GO:0005515///protein binding+++GO:0008929///methylglyoxal synthase activity+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0019242///methylglyoxal biosynthetic process+++GO:0019563///glycerol catabolic process+++GO:0019682///glyceraldehyde-3-phosphate metabolic process+++GO:0046166///glyceraldehyde-3-phosphate biosynthetic process 22003 22003 'Tpm1' mRNA 2450 2400 2420 76.17 73.7 80.55 114.88 116.97 117.15 76.80666667 116.3333333 3979 3939 3924 2423.333333 3947.333333 8.80E-28 0.691365062 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05206///MicroRNAs in cancer+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005862///muscle thin filament tropomyosin+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril+++GO:0032059///bleb+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0051015///actin filament binding+++GO:0097718///disordered domain specific binding GO:0001701///in utero embryonic development+++GO:0003065///positive regulation of heart rate by epinephrine+++GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0008360///regulation of cell shape+++GO:0009790///embryo development+++GO:0030049///muscle filament sliding+++GO:0030336///negative regulation of cell migration+++GO:0031529///ruffle organization+++GO:0032781///positive regulation of ATPase activity+++GO:0042060///wound healing+++GO:0043462///regulation of ATPase activity+++GO:0045214///sarcomere organization+++GO:0045785///positive regulation of cell adhesion+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051693///actin filament capping+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0060048///cardiac muscle contraction+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration 22004 22004 'Tpm2' mRNA 92 94 96 3 2.56 2.82 7.15 7.07 8.94 2.793333333 7.72 252 245 295 94 264 2.22E-14 1.477550656 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005862///muscle thin filament tropomyosin+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0043462///regulation of ATPase activity 22017 22017 'Tpmt' mRNA 145.94 163.99 156.73 3.17 3.33 3.69 7.07 6.3 7.13 3.396666667 6.833333333 357.46 316.07 352.08 155.5533333 341.87 2.27E-12 1.130582875 00983///Drug metabolism - other enzymes GO:0005737///cytoplasm GO:0008119///thiopurine S-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:1904047///S-adenosyl-L-methionine binding GO:0006805///xenobiotic metabolic process+++GO:0017144///drug metabolic process+++GO:0032259///methylation 22018 22018 'Tpo' mRNA 152 160 178 2.49 2.56 3.1 0.33 0.31 0.31 2.716666667 0.316666667 23 21 21 163.3333333 21.66666667 2.72E-23 -2.930272496 00350///Tyrosine metabolism+++04918///Thyroid hormone synthesis+++05320///Autoimmune thyroid disease GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004447///iodide peroxidase activity+++GO:0004601///peroxidase activity+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0006590///thyroid hormone generation+++GO:0006979///response to oxidative stress+++GO:0035162///embryonic hemopoiesis+++GO:0042446///hormone biosynthetic process+++GO:0042744///hydrogen peroxide catabolic process 22019 22019 'Tpp2' mRNA 578 677 710 6.65 7.66 8.66 12.28 10.36 11.19 7.656666667 11.27666667 1231 1013 1085 655 1109.666667 7.56E-11 0.743943454 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0004177///aminopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008240///tripeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0042802///identical protein binding GO:0006508///proteolysis 22021 22021 'Tpst1' mRNA 401 399 236 11.75 11.3 7.22 6.66 11.99 10.04 10.09 9.563333333 261 463 384 345.3333333 369.3333333 0.730938008 0.101383129 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0008146///sulfotransferase activity+++GO:0008476///protein-tyrosine sulfotransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity GO:0006478///peptidyl-tyrosine sulfation 22022 22022 'Tpst2' mRNA 1169 1229 1178 38.46 39.93 41.45 50.27 49.75 43.78 39.94666667 47.93333333 1753 1684 1476 1192 1637.666667 3.85E-07 0.445743875 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008476///protein-tyrosine sulfotransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity GO:0006478///peptidyl-tyrosine sulfation+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0060468///prevention of polyspermy 22025 22025 'Nr2c1' mRNA 635 670 668 8.11 8.41 9.1 6.31 5.87 6.72 8.54 6.3 558 503 575 657.6666667 545.3333333 0.016723039 -0.283580132 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0048856///anatomical structure development" 22026 22026 'Nr2c2' mRNA 555.65 508.65 505.07 4.57 4.32 4.36 2.72 2.37 2.26 4.416666667 2.45 352.61 289.37 286.68 523.1233333 309.5533333 5.89E-09 -0.771561309 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0021549///cerebellum development+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0038066///p38MAPK cascade+++GO:0040019///positive regulation of embryonic development+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048520///positive regulation of behavior+++GO:0048856///anatomical structure development+++GO:0051321///meiotic cell cycle" 22027 22027 'Hsp90b1' mRNA 15008 15627 14929 300.65 308.13 317.25 318.57 311.05 316.45 308.6766667 315.3566667 18295 17445 17596 15188 17778.66667 1.91E-05 0.214906383 04141///Protein processing in endoplasmic reticulum+++04151///PI3K-Akt signaling pathway+++04657///IL-17 signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++05132///Salmonella infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019903///protein phosphatase binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0051082///unfolded protein binding "GO:0001666///response to hypoxia+++GO:0006457///protein folding+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0031247///actin rod assembly+++GO:0043066///negative regulation of apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0071318///cellular response to ATP" 22029 22029 'Traf1' mRNA 400 391 397 10.09 9.5 10.83 6.63 5.15 6.64 10.14 6.14 296 224 275 396 265 8.37E-05 -0.594019468 04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04668///TNF signaling pathway+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer GO:0005737///cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0098802///plasma membrane receptor complex GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070534///protein K63-linked ubiquitination+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 22030 22030 'Traf2' mRNA 639 552 639 11.45 9.74 12.17 12.58 12.96 12.89 11.12 12.81 810 813 800 610 807.6666667 7.11E-04 0.390661267 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04071///Sphingolipid signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04217///Necroptosis+++04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05160///Hepatitis C+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer+++05417///Lipid and atherosclerosis GO:0000151///ubiquitin ligase complex+++GO:0002947///tumor necrosis factor receptor superfamily complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0012506///vesicle membrane+++GO:0032991///protein-containing complex+++GO:0035631///CD40 receptor complex+++GO:0045121///membrane raft+++GO:0097057///TRAF2-GSTP1 complex+++GO:0098802///plasma membrane receptor complex+++GO:1990604///IRE1-TRAF2-ASK1 complex "GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005174///CD40 receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030674///protein binding, bridging+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0042802///identical protein binding+++GO:0043120///tumor necrosis factor binding+++GO:0044877///protein-containing complex binding+++GO:0046625///sphingolipid binding+++GO:0046872///metal ion binding" GO:0002637///regulation of immunoglobulin production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0016567///protein ubiquitination+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030163///protein catabolic process+++GO:0032743///positive regulation of interleukin-2 production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0034622///cellular protein-containing complex assembly+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046328///regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0048255///mRNA stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0071732///cellular response to nitric oxide+++GO:0097300///programmed necrotic cell death+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 22031 22031 'Traf3' mRNA 870 833 810 6.44 6.09 6.39 4.4 4.09 4.34 6.306666667 4.276666667 690 619 661 837.6666667 656.6666667 3.02E-04 -0.363425959 04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0035631///CD40 receptor complex+++GO:0098802///plasma membrane receptor complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001817///regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008063///Toll signaling pathway+++GO:0030162///regulation of proteolysis+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032648///regulation of interferon-beta production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0050688///regulation of defense response to virus+++GO:0070534///protein K63-linked ubiquitination 22032 22032 'Traf4' mRNA 888 846 516 16.12 15.14 9.94 8.71 12.94 10.94 13.73333333 10.86333333 551 801 670 750 674 0.686004242 -0.150812441 04214///Apoptosis - fly+++04657///IL-17 signaling pathway+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0098802///plasma membrane receptor complex GO:0005164///tumor necrosis factor receptor binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050699///WW domain binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007275///multicellular organism development+++GO:0007585///respiratory gaseous exchange+++GO:0030323///respiratory tube development+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070534///protein K63-linked ubiquitination 22033 22033 'Traf5' mRNA 72 66 55 1.8 1.63 1.46 2.94 2.52 2.55 1.63 2.67 135 113 114 64.33333333 120.6666667 6.70E-04 0.897475478 04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0035631///CD40 receptor complex+++GO:0098802///plasma membrane receptor complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade+++GO:0048255///mRNA stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0097400///interleukin-17-mediated signaling pathway 22034 22034 'Traf6' mRNA 618 657 628 5.33 5.61 5.78 5.51 5.36 5.78 5.573333333 5.55 730 692 742 634.3333333 721.3333333 0.126681872 0.173317762 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal+++04144///Endocytosis+++04214///Apoptosis - fly+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04722///Neurotrophin signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05222///Small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0032991///protein-containing complex+++GO:0035631///CD40 receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0098802///plasma membrane receptor complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031996///thioesterase binding+++GO:0032813///tumor necrosis factor receptor superfamily binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043422///protein kinase B binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0001503///ossification+++GO:0001701///in utero embryonic development+++GO:0001843///neural tube closure+++GO:0002376///immune system process+++GO:0002637///regulation of immunoglobulin production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006955///immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007254///JNK cascade+++GO:0009887///animal organ morphogenesis+++GO:0016567///protein ubiquitination+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030316///osteoclast differentiation+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032147///activation of protein kinase activity+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042088///T-helper 1 type immune response+++GO:0042102///positive regulation of T cell proliferation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042981///regulation of apoptotic process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045453///bone resorption+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046849///bone remodeling+++GO:0048468///cell development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070534///protein K63-linked ubiquitination+++GO:0070555///response to interleukin-1+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:2000679///positive regulation of transcription regulatory region DNA binding" 22035 22035 'Tnfsf10' mRNA 101.38 108.54 90.56 1.1 1.15 1.04 1.39 1.43 1.55 1.096666667 1.456666667 147.88 148.49 160 100.16 152.1233333 0.008703001 0.596791261 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04068///FoxO signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04650///Natural killer cell mediated cytotoxicity+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05164///Influenza A+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0008270///zinc ion binding+++GO:0032813///tumor necrosis factor receptor superfamily binding+++GO:0042802///identical protein binding+++GO:0045569///TRAIL binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008584///male gonad development+++GO:0032868///response to insulin+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 22036 22036 'Traip' mRNA 70 52 69 2.01 1.4 1.64 3.11 2.29 3.87 1.683333333 3.09 130 109 164 63.66666667 134.3333333 1.40E-04 1.061355353 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0090734///site of DNA damage GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016567///protein ubiquitination+++GO:0031297///replication fork processing+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032688///negative regulation of interferon-beta production 22037 22037 'Trap1a' mRNA 0 1 0 0 0.05 0 0 0 0.05 0.016666667 0.016666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus 22038 22038 'Plscr1' mRNA 345.18 353.25 377.2 11.22 10.8 12.68 29.12 27.56 28.09 11.56666667 28.25666667 1070.41 983.6 981.72 358.5433333 1011.91 1.73E-43 1.482606001 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix "GO:0000287///magnesium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001618///virus receptor activity+++GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0017128///phospholipid scramblase activity+++GO:0019899///enzyme binding+++GO:0032791///lead ion binding+++GO:0042609///CD4 receptor binding+++GO:0045340///mercury ion binding" GO:0006659///phosphatidylserine biosynthetic process+++GO:0006915///apoptotic process+++GO:0006953///acute-phase response+++GO:0006955///immune response+++GO:0010288///response to lead ion+++GO:0010628///positive regulation of gene expression+++GO:0017121///phospholipid scrambling+++GO:0030099///myeloid cell differentiation+++GO:0032091///negative regulation of protein binding+++GO:0033003///regulation of mast cell activation+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0043065///positive regulation of apoptotic process+++GO:0045071///negative regulation of viral genome replication+++GO:0045089///positive regulation of innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046718///viral entry into host cell+++GO:0050765///negative regulation of phagocytosis+++GO:0051607///defense response to virus+++GO:0060368///regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071345///cellular response to cytokine stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1905820///positive regulation of chromosome separation+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity 22040 22040 'Trex1' mRNA 499 511 469 29.6 29.98 29.51 96.46 96.18 94.17 29.69666667 95.60333333 1862 1809 1756 493 1809 5.58E-111 1.864601103 04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0032993///protein-DNA complex+++GO:0043596///nuclear replication fork "GO:0000287///magnesium ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008301///DNA binding, bending+++GO:0008408///3'-5' exonuclease activity+++GO:0008853///exodeoxyribonuclease III activity+++GO:0016787///hydrolase activity+++GO:0032405///MutLalpha complex binding+++GO:0032407///MutSalpha complex binding+++GO:0032558///adenyl deoxyribonucleotide binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050699///WW domain binding" "GO:0000077///DNA damage checkpoint+++GO:0000738///DNA catabolic process, exonucleolytic+++GO:0001568///blood vessel development+++GO:0001822///kidney development+++GO:0002250///adaptive immune response+++GO:0002251///organ or tissue specific immune response+++GO:0002253///activation of immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002383///immune response in brain or nervous system+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0002457///T cell antigen processing and presentation+++GO:0002637///regulation of immunoglobulin production+++GO:0003007///heart morphogenesis+++GO:0003015///heart process+++GO:0003228///atrial cardiac muscle tissue development+++GO:0006091///generation of precursor metabolites and energy+++GO:0006110///regulation of glycolytic process+++GO:0006259///DNA metabolic process+++GO:0006260///DNA replication+++GO:0006304///DNA modification+++GO:0006308///DNA catabolic process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0009411///response to UV+++GO:0010468///regulation of gene expression+++GO:0019217///regulation of fatty acid metabolic process+++GO:0031323///regulation of cellular metabolic process+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032197///transposition, RNA-mediated+++GO:0032479///regulation of type I interferon production+++GO:0032508///DNA duplex unwinding+++GO:0032607///interferon-alpha production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0034599///cellular response to oxidative stress+++GO:0034614///cellular response to reactive oxygen species+++GO:0034644///cellular response to UV+++GO:0035458///cellular response to interferon-beta+++GO:0035781///CD86 biosynthetic process+++GO:0043277///apoptotic cell clearance+++GO:0043457///regulation of cellular respiration+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045184///establishment of protein localization+++GO:0046890///regulation of lipid biosynthetic process+++GO:0050727///regulation of inflammatory response+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0050863///regulation of T cell activation+++GO:0051319///G2 phase+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061635///regulation of protein complex stability+++GO:0071310///cellular response to organic substance+++GO:0071357///cellular response to type I interferon+++GO:0071480///cellular response to gamma radiation+++GO:0072711///cellular response to hydroxyurea+++GO:0097281///immune complex formation+++GO:1904161///DNA synthesis involved in UV-damage excision repair+++GO:1905671///regulation of lysosome organization" 22041 22041 'Trf' mRNA 60488 63613 63765 1454.12 1505.85 1626.12 3280.55 3364.29 3181.75 1528.696667 3275.53 156942 157153 147355 62622 153816.6667 5.59E-113 1.283084945 04066///HIF-1 signaling pathway+++04216///Ferroptosis+++04978///Mineral absorption GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030120///vesicle coat+++GO:0030139///endocytic vesicle+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip+++GO:0055037///recycling endosome+++GO:0097433///dense body+++GO:1990712///HFE-transferrin receptor complex GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0034986///iron chaperone activity+++GO:0046872///metal ion binding+++GO:1990459///transferrin receptor binding "GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007015///actin filament organization+++GO:0007257///activation of JUN kinase activity+++GO:0009617///response to bacterium+++GO:0019731///antibacterial humoral response+++GO:0030316///osteoclast differentiation+++GO:0031643///positive regulation of myelination+++GO:0034756///regulation of iron ion transport+++GO:0042327///positive regulation of phosphorylation+++GO:0045780///positive regulation of bone resorption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0055072///iron ion homeostasis+++GO:0060395///SMAD protein signal transduction+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0071281///cellular response to iron ion+++GO:2000147///positive regulation of cell motility" 22042 22042 'Tfrc' mRNA 911 965 880 9.9 10.31 10.16 7.53 7.6 8.34 10.12333333 7.823333333 797 786 855 918.6666667 812.6666667 0.065063533 -0.187600582 04066///HIF-1 signaling pathway+++04144///Endocytosis+++04145///Phagosome+++04216///Ferroptosis+++04640///Hematopoietic cell lineage GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:1990712///HFE-transferrin receptor complex GO:0003725///double-stranded RNA binding+++GO:0004998///transferrin receptor activity+++GO:0005381///iron ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006508///proteolysis+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0010628///positive regulation of gene expression+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0030316///osteoclast differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031334///positive regulation of protein complex assembly+++GO:0031623///receptor internalization+++GO:0031668///cellular response to extracellular stimulus+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033572///transferrin transport+++GO:0034755///iron ion transmembrane transport+++GO:0035556///intracellular signal transduction+++GO:0035690///cellular response to drug+++GO:0042102///positive regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045780///positive regulation of bone resorption+++GO:0045830///positive regulation of isotype switching+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071281///cellular response to iron ion+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1990830///cellular response to leukemia inhibitory factor 22044 22044 'Trh' mRNA 0 1 1 0 0.04 0.05 0.26 0.12 0.04 0.03 0.14 7 3 1 0.666666667 3.666666667 0.254321175 2.429104202 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030120///vesicle coat+++GO:0030139///endocytic vesicle+++GO:0030141///secretory granule+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip+++GO:0055037///recycling endosome+++GO:0097433///dense body+++GO:1990712///HFE-transferrin receptor complex GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008199///ferric iron binding+++GO:0008437///thyrotropin-releasing hormone activity+++GO:0034986///iron chaperone activity+++GO:0046872///metal ion binding+++GO:1990459///transferrin receptor binding "GO:0001666///response to hypoxia+++GO:0001692///histamine metabolic process+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007015///actin filament organization+++GO:0007628///adult walking behavior+++GO:0009409///response to cold+++GO:0009617///response to bacterium+++GO:0009749///response to glucose+++GO:0009755///hormone-mediated signaling pathway+++GO:0014050///negative regulation of glutamate secretion+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0014070///response to organic cyclic compound+++GO:0019731///antibacterial humoral response+++GO:0030316///osteoclast differentiation+++GO:0031643///positive regulation of myelination+++GO:0032024///positive regulation of insulin secretion+++GO:0034756///regulation of iron ion transport+++GO:0042327///positive regulation of phosphorylation+++GO:0042755///eating behavior+++GO:0045471///response to ethanol+++GO:0045780///positive regulation of bone resorption+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0051412///response to corticosterone+++GO:0055072///iron ion homeostasis+++GO:0060395///SMAD protein signal transduction+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0071281///cellular response to iron ion+++GO:2000147///positive regulation of cell motility+++GO:2000252///negative regulation of feeding behavior" 22051 22051 'Trip6' mRNA 1261 1242 1233 41.41 40.2 42.96 37.69 37.82 36.23 41.52333333 37.24666667 1319 1292 1227 1245.333333 1279.333333 0.823271691 0.026494929 04621///NOD-like receptor signaling pathway GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0030335///positive regulation of cell migration+++GO:0043009///chordate embryonic development+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 22057 22057 'Tob1' mRNA 2488 2725 2145 61.1 65.91 55.97 34.31 37.01 37.22 60.99333333 36.18 1604 1692 1685 2452.666667 1660.333333 5.04E-13 -0.569934367 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046332///SMAD binding "GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0060390///regulation of SMAD protein signal transduction+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" 22059 22059 'Trp53' mRNA 1380 1571 1479 43.34 48.92 49.87 72.63 74.55 70.95 47.37666667 72.71 2614 2615 2471 1476.666667 2566.666667 1.06E-24 0.785412159 01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04071///Sphingolipid signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04137///Mitophagy - animal+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04216///Ferroptosis+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04722///Neurotrophin signaling pathway+++04919///Thyroid hormone signaling pathway+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05131///Shigellosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005667///transcription factor complex+++GO:0005669///transcription factor TFIID complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0035861///site of double-strand break+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002020///protease binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035033///histone deacetylase regulator activity+++GO:0035035///histone acetyltransferase binding+++GO:0036310///annealing helicase activity+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0051087///chaperone binding+++GO:0051721///protein phosphatase 2A binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0097718///disordered domain specific binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000733///DNA strand renaturation+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001836///release of cytochrome c from mitochondria+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002309///T cell proliferation involved in immune response+++GO:0002326///B cell lineage commitment+++GO:0002360///T cell lineage commitment+++GO:0002687///positive regulation of leukocyte migration+++GO:0002931///response to ischemia+++GO:0006289///nucleotide-excision repair+++GO:0006302///double-strand break repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0006979///response to oxidative stress+++GO:0006983///ER overload response+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007346///regulation of mitotic cell cycle+++GO:0007369///gastrulation+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007568///aging+++GO:0007569///cell aging+++GO:0007623///circadian rhythm+++GO:0008104///protein localization+++GO:0008156///negative regulation of DNA replication+++GO:0008285///negative regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0009299///mRNA transcription+++GO:0009303///rRNA transcription+++GO:0009410///response to xenobiotic stimulus+++GO:0009411///response to UV+++GO:0009651///response to salt stress+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010035///response to inorganic substance+++GO:0010038///response to metal ion+++GO:0010165///response to X-ray+++GO:0010224///response to UV-B+++GO:0010243///response to organonitrogen compound+++GO:0010332///response to gamma radiation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0012501///programmed cell death+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process+++GO:0021549///cerebellum development+++GO:0030308///negative regulation of cell growth+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031000///response to caffeine+++GO:0031065///positive regulation of histone deacetylation+++GO:0031497///chromatin assembly+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032526///response to retinoic acid+++GO:0033077///T cell differentiation in thymus+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0033552///response to vitamin B3+++GO:0033554///cellular response to stress+++GO:0034097///response to cytokine+++GO:0034103///regulation of tissue remodeling+++GO:0034605///cellular response to heat+++GO:0034613///cellular protein localization+++GO:0034614///cellular response to reactive oxygen species+++GO:0034644///cellular response to UV+++GO:0035264///multicellular organism growth+++GO:0035690///cellular response to drug+++GO:0035794///positive regulation of mitochondrial membrane permeability+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043200///response to amino acid+++GO:0043504///mitochondrial DNA repair+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043523///regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045471///response to ethanol+++GO:0045787///positive regulation of cell cycle+++GO:0045861///negative regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046677///response to antibiotic+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048511///rhythmic process+++GO:0048512///circadian behavior+++GO:0048539///bone marrow development+++GO:0048568///embryonic organ development+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0051262///protein tetramerization+++GO:0051276///chromosome organization+++GO:0051402///neuron apoptotic process+++GO:0051453///regulation of intracellular pH+++GO:0051726///regulation of cell cycle+++GO:0051974///negative regulation of telomerase activity+++GO:0055093///response to hyperoxia+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060411///cardiac septum morphogenesis+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0065003///protein-containing complex assembly+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070243///regulation of thymocyte apoptotic process+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0070266///necroptotic process+++GO:0071417///cellular response to organonitrogen compound+++GO:0071456///cellular response to hypoxia+++GO:0071479///cellular response to ionizing radiation+++GO:0071480///cellular response to gamma radiation+++GO:0071494///cellular response to UV-C+++GO:0072331///signal transduction by p53 class mediator+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0072717///cellular response to actinomycin D+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090343///positive regulation of cell aging+++GO:0090399///replicative senescence+++GO:0090403///oxidative stress-induced premature senescence+++GO:0097252///oligodendrocyte apoptotic process+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1901525///negative regulation of mitophagy+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902253///regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903205///regulation of hydrogen peroxide-induced cell death+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1904024///negative regulation of glucose catabolic process to lactate via pyruvate+++GO:1905856///negative regulation of pentose-phosphate shunt+++GO:1990144///intrinsic apoptotic signaling pathway in response to hypoxia+++GO:1990248///regulation of transcription from RNA polymerase II promoter in response to DNA damage+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:2000269///regulation of fibroblast apoptotic process+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000772///regulation of cellular senescence+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 22061 22061 'Trp63' mRNA 6 9 12 0.1 0.15 0.15 0.18 0.14 0.07 0.133333333 0.13 15 14 5 9 11.33333333 0.777050912 0.308940512 04214///Apoptosis - fly+++04391///Hippo signaling pathway - fly+++05206///MicroRNAs in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0050699///WW domain binding+++GO:0097371///MDM2/MDM4 family protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001736///establishment of planar polarity+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0001942///hair follicle development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002064///epithelial cell development+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007389///pattern specification process+++GO:0007499///ectoderm and mesoderm interaction+++GO:0007568///aging+++GO:0007569///cell aging+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0009887///animal organ morphogenesis+++GO:0009913///epidermal cell differentiation+++GO:0009954///proximal/distal pattern formation+++GO:0010259///multicellular organism aging+++GO:0010481///epidermal cell division+++GO:0010482///regulation of epidermal cell division+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030850///prostate gland development+++GO:0030855///epithelial cell differentiation+++GO:0030859///polarized epithelial cell differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0032502///developmental process+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0036342///post-anal tail morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043066///negative regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043589///skin morphogenesis+++GO:0043616///keratinocyte proliferation+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048485///sympathetic nervous system development+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0048807///female genitalia morphogenesis+++GO:0051262///protein tetramerization+++GO:0051402///neuron apoptotic process+++GO:0060157///urinary bladder development+++GO:0060197///cloacal septation+++GO:0060513///prostatic bud formation+++GO:0060529///squamous basal epithelial stem cell differentiation involved in prostate gland acinus development+++GO:0061436///establishment of skin barrier+++GO:0098773///skin epidermis development+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:1904674///positive regulation of somatic stem cell population maintenance+++GO:1904888///cranial skeletal system development+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:2000381///negative regulation of mesoderm development+++GO:2000773///negative regulation of cellular senescence+++GO:2001235///positive regulation of apoptotic signaling pathway" 22062 22062 'Trp73' mRNA 4 1 2 0.05 0.01 0.03 0 0 0.02 0.03 0.006666667 0 0 2 2.333333333 0.666666667 0.493427714 -1.814353534 04115///p53 signaling pathway+++04390///Hippo signaling pathway+++04722///Neurotrophin signaling pathway+++05162///Measles GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0097371///MDM2/MDM4 family protein binding" "GO:0000187///activation of MAPK activity+++GO:0001822///kidney development+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007346///regulation of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010243///response to organonitrogen compound+++GO:0010468///regulation of gene expression+++GO:0021766///hippocampus development+++GO:0030900///forebrain development+++GO:0033326///cerebrospinal fluid secretion+++GO:0042493///response to drug+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043508///negative regulation of JUN kinase activity+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045665///negative regulation of neuron differentiation+++GO:0045793///positive regulation of cell size+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048546///digestive tract morphogenesis+++GO:0048666///neuron development+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0051262///protein tetramerization+++GO:0051726///regulation of cell cycle+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0071158///positive regulation of cell cycle arrest+++GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2001235///positive regulation of apoptotic signaling pathway" 22063 22063 'Trpc1' mRNA 128 132 117 1.89 1.93 1.93 1.51 1.16 1.42 1.916666667 1.363333333 115 81 99 125.6666667 98.33333333 0.164450404 -0.366425977 04360///Axon guidance+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04929///GnRH secretion+++04972///Pancreatic secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030017///sarcomere+++GO:0032991///protein-containing complex+++GO:0034703///cation channel complex+++GO:0043034///costamere+++GO:0043235///receptor complex+++GO:0045121///membrane raft "GO:0005102///signaling receptor binding+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015279///store-operated calcium channel activity+++GO:0044325///ion channel binding+++GO:0051117///ATPase binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0042438///melanin biosynthetic process+++GO:0046541///saliva secretion+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport 22065 22065 'Trpc3' mRNA 34 31 29 0.5 0.45 0.45 0.23 0.2 0.12 0.466666667 0.183333333 18 15 9 31.33333333 14 0.035002254 -1.174781548 04360///Axon guidance+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034703///cation channel complex "GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005262///calcium channel activity+++GO:0015279///store-operated calcium channel activity+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0007338///single fertilization+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0033198///response to ATP+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:1903244///positive regulation of cardiac muscle hypertrophy in response to stress 22066 22066 'Trpc4' mRNA 10 10 8 0.16 0.15 0.14 0 0 0.02 0.15 0.006666667 0 0 1 9.333333333 0.333333333 0.004433196 -4.710855975 04360///Axon guidance+++04745///Phototransduction - fly+++04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030863///cortical cytoskeleton+++GO:0032991///protein-containing complex+++GO:0034703///cation channel complex+++GO:0034704///calcium channel complex+++GO:0045121///membrane raft "GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0015279///store-operated calcium channel activity+++GO:0045296///cadherin binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0014051///gamma-aminobutyric acid secretion+++GO:0048709///oligodendrocyte differentiation+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051924///regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0099605///regulation of action potential firing rate 22067 22067 'Trpc5' mRNA 11.32 2 6.99 0.07 0.01 0.05 0.02 0.02 0.02 0.043333333 0.02 3.1 4.11 4.25 6.77 3.82 0.569420399 -0.801035713 04360///Axon guidance+++04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0034703///cation channel complex+++GO:0034704///calcium channel complex+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft "GO:0003779///actin binding+++GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015279///store-operated calcium channel activity+++GO:0030276///clathrin binding+++GO:0042805///actinin binding+++GO:0051117///ATPase binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0030182///neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045773///positive regulation of axon extension+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0051402///neuron apoptotic process+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:1902630///regulation of membrane hyperpolarization 22068 22068 'Trpc6' mRNA 23.03 12.22 4.78 0.39 0.2 0.09 0 0.02 0.03 0.226666667 0.016666667 0 1 2 13.34333333 1 0.005515256 -3.685912104 04022///cGMP-PKG signaling pathway+++04360///Axon guidance GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034703///cation channel complex+++GO:0036057///slit diaphragm "GO:0003779///actin binding+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015279///store-operated calcium channel activity+++GO:0030276///clathrin binding+++GO:0042803///protein homodimerization activity+++GO:0042805///actinin binding+++GO:0051117///ATPase binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007338///single fertilization+++GO:0007568///aging+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0030182///neuron differentiation+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051928///positive regulation of calcium ion transport+++GO:0055085///transmembrane transport+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070588///calcium ion transmembrane transport+++GO:0071456///cellular response to hypoxia 22070 22070 'Tpt1' mRNA 5468 5362 5404 402.52 390.83 422.21 592.91 561.65 596.35 405.1866667 583.6366667 9224 8514 8961 5411.333333 8899.666667 7.07E-36 0.704485374 GO:0000922///spindle pole+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding GO:0007283///spermatogenesis+++GO:0019827///stem cell population maintenance+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000384///negative regulation of ectoderm development 22072 22072 'Prss2' mRNA 1 0 0 0.08 0 0 0.36 0.07 0.15 0.026666667 0.193333333 5 1 2 0.333333333 2.666666667 0.259975879 2.870505452 04080///Neuroactive ligand-receptor interaction+++04972///Pancreatic secretion+++04974///Protein digestion and absorption+++05164///Influenza A GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007584///response to nutrient+++GO:0007586///digestion+++GO:0010033///response to organic substance+++GO:0030574///collagen catabolic process+++GO:0031000///response to caffeine+++GO:0035094///response to nicotine 22083 22083 'Ctr9' mRNA 1199 1248 1379 15 15.35 18.3 16.26 16.84 15.98 16.21666667 16.36 1496 1514 1424 1275.333333 1478 0.056254229 0.197542802 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016593///Cdc73/Paf1 complex+++GO:0016607///nuclear speck+++GO:0035327///transcriptionally active chromatin GO:0000993///RNA polymerase II complex binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001711///endodermal cell fate commitment+++GO:0001826///inner cell mass cell differentiation+++GO:0001829///trophectodermal cell differentiation+++GO:0001832///blastocyst growth+++GO:0001835///blastocyst hatching+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0007259///JAK-STAT cascade+++GO:0010390///histone monoubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0016570///histone modification+++GO:0019827///stem cell population maintenance+++GO:0033523///histone H2B ubiquitination+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0080182///histone H3-K4 trimethylation+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:2000653///regulation of genetic imprinting+++GO:2001162///positive regulation of histone H3-K79 methylation+++GO:2001168///positive regulation of histone H2B ubiquitination" 22084 22084 'Tsc2' mRNA 2208.62 2104.45 2128 20.64 19.69 21.13 13.68 12.27 13.6 20.48666667 13.18333333 1675.99 1476.5 1616.76 2147.023333 1589.75 4.63E-09 -0.447316298 04072///Phospholipase D signaling pathway+++04115///p53 signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005901///caveola+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0033596///TSC1-TSC2 complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0051879///Hsp90 protein binding+++GO:0071889///14-3-3 protein binding GO:0001666///response to hypoxia+++GO:0001843///neural tube closure+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0007507///heart development+++GO:0007568///aging+++GO:0008104///protein localization+++GO:0008285///negative regulation of cell proliferation+++GO:0010508///positive regulation of autophagy+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010763///positive regulation of fibroblast migration+++GO:0010976///positive regulation of neuron projection development+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016239///positive regulation of macroautophagy+++GO:0016242///negative regulation of macroautophagy+++GO:0030010///establishment of cell polarity+++GO:0030030///cell projection organization+++GO:0030100///regulation of endocytosis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0032869///cellular response to insulin stimulus+++GO:0034394///protein localization to cell surface+++GO:0035176///social behavior+++GO:0043276///anoikis+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043491///protein kinase B signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0044861///protein transport into plasma membrane raft+++GO:0045184///establishment of protein localization+++GO:0045785///positive regulation of cell adhesion+++GO:0045792///negative regulation of cell size+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046323///glucose import+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048550///negative regulation of pinocytosis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050771///negative regulation of axonogenesis+++GO:0050918///positive chemotaxis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0051726///regulation of cell cycle+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060999///positive regulation of dendritic spine development+++GO:0098976///excitatory chemical synaptic transmission+++GO:0098977///inhibitory chemical synaptic transmission+++GO:0099175///regulation of postsynapse organization+++GO:1904262///negative regulation of TORC1 signaling+++GO:1905563///negative regulation of vascular endothelial cell proliferation 22088 22088 'Tsg101' mRNA 1727 1872 1788 51.68 55.17 57.2 60.44 60.07 60.4 54.68333333 60.30333333 2347 2258 2256 1795.666667 2287 3.59E-06 0.336565058 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0070062///extracellular exosome+++GO:0090543///Flemming body GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding+++GO:0046790///virion binding+++GO:0048306///calcium-dependent protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0006464///cellular protein modification process+++GO:0006513///protein monoubiquitination+++GO:0006858///extracellular transport+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0008285///negative regulation of cell proliferation+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016032///viral process+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0040008///regulation of growth+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0043405///regulation of MAP kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046755///viral budding+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:1902188///positive regulation of viral release from host cell+++GO:1903543///positive regulation of exosomal secretion+++GO:1903551///regulation of extracellular exosome assembly+++GO:1903774///positive regulation of viral budding via host ESCRT complex+++GO:1990182///exosomal secretion+++GO:2000397///positive regulation of ubiquitin-dependent endocytosis" 22092 22092 'Rsph1' mRNA 1025 942 945 58.07 52.79 56.87 9.57 9.82 9.8 55.91 9.73 194 194 192 970.6666667 193.3333333 4.96E-90 -2.339799175 GO:0000794///condensed nuclear chromosome+++GO:0001520///outer dense fiber+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0072687///meiotic spindle GO:0005515///protein binding GO:0007286///spermatid development+++GO:0035082///axoneme assembly+++GO:0051321///meiotic cell cycle 22094 22094 'Tshb' mRNA 11 5 3 0.28 0.12 0.13 0.05 0 0 0.176666667 0.016666667 2 0 0 6.333333333 0.666666667 0.069374711 -3.258552031 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04918///Thyroid hormone synthesis+++04923///Regulation of lipolysis in adipocytes+++05320///Autoimmune thyroid disease GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0033189///response to vitamin A+++GO:0043627///response to estrogen+++GO:0051592///response to calcium ion 22095 22095 'Tshr' mRNA 0 1 0 0 0.01 0 0 0.01 0 0.003333333 0.003333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04918///Thyroid hormone synthesis+++04923///Regulation of lipolysis in adipocytes+++05320///Autoimmune thyroid disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043235///receptor complex+++GO:0045121///membrane raft GO:0004930///G protein-coupled receptor activity+++GO:0004996///thyroid-stimulating hormone receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016500///protein-hormone receptor activity+++GO:0038023///signaling receptor activity+++GO:0044877///protein-containing complex binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0008284///positive regulation of cell proliferation+++GO:0008344///adult locomotory behavior+++GO:0009755///hormone-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0038194///thyroid-stimulating hormone signaling pathway+++GO:0040012///regulation of locomotion+++GO:0040018///positive regulation of multicellular organism growth+++GO:0060119///inner ear receptor cell development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0071542///dopaminergic neuron differentiation+++GO:0090103///cochlea morphogenesis+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1904588///cellular response to glycoprotein+++GO:1905229///cellular response to thyrotropin-releasing hormone 22099 22099 'Tsn' mRNA 2861 2901 2897 47.96 47.85 51.5 47.78 49.21 47.14 49.10333333 48.04333333 3280 3299 3134 2886.333333 3237.666667 0.032828098 0.153107887 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding GO:0016070///RNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 22110 22110 'Tspyl1' mRNA 3187 3236 3115 65.45 65.42 67.86 51.01 51.99 50.98 66.24333333 51.32666667 2857 2843.99 2764.98 3179.333333 2821.99 0.004968469 -0.184145308 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003682///chromatin binding+++GO:0019899///enzyme binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly 22113 22113 'Phlda2' mRNA 0 5 0 0 0.38 0 0.16 0.6 0.47 0.126666667 0.41 3 7 9 1.666666667 6.333333333 0.238123683 1.95343837 GO:0005737///cytoplasm+++GO:0016020///membrane GO:1901981///phosphatidylinositol phosphate binding GO:0001890///placenta development+++GO:0009887///animal organ morphogenesis+++GO:0010468///regulation of gene expression+++GO:0030334///regulation of cell migration+++GO:0043065///positive regulation of apoptotic process+++GO:0045995///regulation of embryonic development+++GO:0060721///regulation of spongiotrophoblast cell proliferation+++GO:0070873///regulation of glycogen metabolic process+++GO:1903547///regulation of growth hormone activity 22114 22114 'Tssk1' mRNA 1 5 2 0.04 0.2 0.09 0.18 0.15 0.11 0.11 0.146666667 5 4 3 2.666666667 4 0.748901072 0.580969947 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0010467///gene expression+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0043588///skin development 22115 22115 'Tssk2' mRNA 0 1 0 0 0.04 0 0.04 0 0.04 0.013333333 0.026666667 1 0 1 0.333333333 0.666666667 0.863090843 0.873430513 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation 22116 22116 'Tsks' mRNA 41 33 25 1.27 1 0.84 0.74 0.83 0.59 1.036666667 0.72 28 30 21 33 26.33333333 0.562126778 -0.330911657 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle GO:0016301///kinase activity+++GO:0019901///protein kinase binding GO:0010923///negative regulation of phosphatase activity+++GO:0016310///phosphorylation 22117 22117 'Tst' mRNA 910 920 922 51.62 51.57 55.49 43.71 46.1 45.48 52.89333333 45.09666667 884 909 889 917.3333333 894 0.6953238 -0.049423794 00270///Cysteine and methionine metabolism+++00920///Sulfur metabolism+++04122///Sulfur relay system GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix GO:0003723///RNA binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0008097///5S rRNA binding+++GO:0016740///transferase activity+++GO:0016783///sulfurtransferase activity GO:0019346///transsulfuration+++GO:0030855///epithelial cell differentiation+++GO:0035928///rRNA import into mitochondrion+++GO:0051029///rRNA transport 22121 22121 'Rpl13a' mRNA 5991 5827 5458 371.01 356.79 358.64 433.19 452.38 441.01 362.1466667 442.1933333 8021 8165 7892 5758.666667 8026 1.94E-18 0.468406145 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0097452///GAIT complex+++GO:1990904///ribonucleoprotein complex GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0032496///response to lipopolysaccharide+++GO:0042592///homeostatic process+++GO:0048246///macrophage chemotaxis+++GO:0060425///lung morphogenesis+++GO:0071346///cellular response to interferon-gamma+++GO:1901194///negative regulation of formation of translation preinitiation complex 22122 22122 'Gfus' mRNA 630 611 643 28.35 27.29 30.89 34.2 35.2 36.19 28.84333333 35.19666667 869 872 888 628 876.3333333 5.35E-06 0.467707189 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars "GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0047918///GDP-mannose 3,5-epimerase activity+++GO:0050577///GDP-L-fucose synthase activity" GO:0001913///T cell mediated cytotoxicity+++GO:0008152///metabolic process+++GO:0009226///nucleotide-sugar biosynthetic process+++GO:0010595///positive regulation of endothelial cell migration+++GO:0019673///GDP-mannose metabolic process+++GO:0042351///'de novo' GDP-L-fucose biosynthetic process+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin 22123 22123 'Psmd3' mRNA 2256 2298 2273 59.38 59.57 63.47 67.18 63.63 66.95 60.80666667 65.92 2935 2714 2831 2275.666667 2826.666667 1.11E-05 0.299806877 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005838///proteasome regulatory particle+++GO:0005886///plasma membrane+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0022624///proteasome accessory complex+++GO:0030054///cell junction+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0045202///synapse" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0030234///enzyme regulator activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032011///ARF protein signal transduction+++GO:0032012///regulation of ARF protein signal transduction+++GO:0042176///regulation of protein catabolic process+++GO:0050790///regulation of catalytic activity 22127 22127 'Tsx' mRNA 16 11 15 1.32 0.87 1.16 0.46 0.5 0.55 1.116666667 0.503333333 7 7 7 14 7 0.228304338 -1.015615625 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0030534///adult behavior 22129 22129 'Ttc3' mRNA 5167.63 5126.92 4730.98 39.42 38.32 38.23 25.61 25.43 24.12 38.65666667 25.05333333 3881.42 3733.79 3535.04 5008.51 3716.75 1.97E-14 -0.441270255 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005773///vacuole+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010771///negative regulation of cell morphogenesis involved in differentiation+++GO:0016567///protein ubiquitination+++GO:0045665///negative regulation of neuron differentiation+++GO:0070936///protein K48-linked ubiquitination 22130 22130 'Ttf1' mRNA 605.41 549.9 598.13 7.83 6.99 8.2 7.21 6.68 7.04 7.673333333 6.976666667 644.03 585.72 610.33 584.48 613.36 0.719979919 0.055750379 04918///Thyroid hormone synthesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding "GO:0006338///chromatin remodeling+++GO:0006353///DNA-templated transcription, termination+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006363///termination of RNA polymerase I transcription+++GO:0008156///negative regulation of DNA replication" 22134 22134 'Tgoln1' mRNA 5152 5332 5622 54.76 55.73 63.39 54.66 51.95 51.48 57.96 52.69666667 5920 5497 5401 5368.666667 5606 0.605362619 0.04725471 GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030140///trans-Golgi network transport vesicle 22137 22137 'Ttk' mRNA 8 4 3 0.15 0.07 0.06 1.76 1.63 1.29 0.093333333 1.56 107 95 76 5 92.66666667 8.81E-17 4.202682495 04110///Cell cycle GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043515///kinetochore binding GO:0006468///protein phosphorylation+++GO:0007059///chromosome segregation+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0016310///phosphorylation+++GO:0016321///female meiosis chromosome segregation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033316///meiotic spindle assembly checkpoint+++GO:0034501///protein localization to kinetochore+++GO:0034502///protein localization to chromosome+++GO:0046777///protein autophosphorylation+++GO:0051304///chromosome separation+++GO:0098768///meiotic prometaphase I+++GO:1903096///protein localization to meiotic spindle midzone 22138 22138 'Ttn' mRNA 107 138.98 106 0.1 0.11 0.08 0.02 0.04 0.03 0.096666667 0.03 41 44.01 38.91 117.3266667 41.30666667 1.16E-07 -1.521038297 05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005859///muscle myosin complex+++GO:0005865///striated muscle thin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0031672///A band+++GO:0031674///I band GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008307///structural constituent of muscle+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030506///ankyrin binding+++GO:0031433///telethonin binding+++GO:0042802///identical protein binding+++GO:0042805///actinin binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051371///muscle alpha-actinin binding+++GO:0097493///structural molecule activity conferring elasticity GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0003007///heart morphogenesis+++GO:0003300///cardiac muscle hypertrophy+++GO:0006468///protein phosphorylation+++GO:0006936///muscle contraction+++GO:0007507///heart development+++GO:0007512///adult heart development+++GO:0010628///positive regulation of gene expression+++GO:0010737///protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021591///ventricular system development+++GO:0030240///skeletal muscle thin filament assembly+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0035995///detection of muscle stretch+++GO:0043056///forward locomotion+++GO:0045214///sarcomere organization+++GO:0045859///regulation of protein kinase activity+++GO:0048739///cardiac muscle fiber development+++GO:0048769///sarcomerogenesis+++GO:0050714///positive regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0051592///response to calcium ion+++GO:0055002///striated muscle cell development+++GO:0055003///cardiac myofibril assembly+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060419///heart growth+++GO:1901897///regulation of relaxation of cardiac muscle 22139 22139 'Ttr' mRNA 1988 1990 1935 160.55 159.95 165.44 18.01 20.56 17.74 161.98 18.77 262 281 245 1971 262.6666667 3.15E-206 -2.91934783 04918///Thyroid hormone synthesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0070324///thyroid hormone binding GO:0006144///purine nucleobase metabolic process+++GO:0007165///signal transduction+++GO:0042572///retinol metabolic process+++GO:0070327///thyroid hormone transport 22141 22141 'Tub' mRNA 33.07 25.3 14.24 0.3 0.22 0.13 0 0.02 0.06 0.216666667 0.026666667 0 2 8 24.20333333 3.333333333 0.00133427 -2.840611814 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane GO:0001664///G protein-coupled receptor binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0120160///intraciliary transport particle A binding "GO:0006909///phagocytosis+++GO:0006910///phagocytosis, recognition+++GO:0007605///sensory perception of sound+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009725///response to hormone+++GO:0042073///intraciliary transport+++GO:0045494///photoreceptor cell maintenance+++GO:0050766///positive regulation of phagocytosis+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:0061512///protein localization to cilium+++GO:0097500///receptor localization to non-motile cilium+++GO:1903441///protein localization to ciliary membrane+++GO:1903546///protein localization to photoreceptor outer segment" 22142 22142 'Tuba1a' mRNA 21464.59 22428 21652.73 790.36 814.33 845.84 783.44 789.56 790.93 816.8433333 787.9766667 24445.18 24041.44 23877.36 21848.44 24121.32667 0.01530028 0.130457513 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0031594///neuromuscular junction+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0050807///regulation of synapse organization 22143 22143 'Tuba1b' mRNA 21443.81 21885.83 21914.13 805.2 810.4 872.97 956.69 950.93 932.14 829.5233333 946.5866667 29270.89 28391.59 27592.94 21747.92333 28418.47333 5.60E-12 0.372652051 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0043209///myelin sheath+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0003725///double-stranded RNA binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0071353///cellular response to interleukin-4 22144 22144 'Tuba3a' mRNA 0 2 0 0 0.07 0 0 0.03 0 0.023333333 0.01 0 1 0 0.666666667 0.333333333 0.863090843 -0.864760308 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0036064///ciliary basal body GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0008150///biological_process 22145 22145 'Tuba4a' mRNA 1398.76 1206.21 1355.46 37.26 31.65 38.45 43.5 42.39 43.53 35.78666667 43.14 1864.96 1775.65 1805.78 1320.143333 1815.463333 5.50E-07 0.445277944 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process 22146 22146 'Tuba1c' mRNA 4371.19 4519.09 4408.02 126.04 128.38 134.84 214.61 197.93 210.06 129.7533333 207.5333333 8556.31 7703.53 8105.69 4432.766667 8121.843333 2.14E-51 0.860347397 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process 22147 22147 'Tuba3b' mRNA 3 1 0 0.11 0.04 0 0 0 0 0.05 0 0 0 0 1.333333333 0 0.489543081 -2.838520661 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0036064///ciliary basal body GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0008150///biological_process 22151 22151 'Tubb2a' mRNA 3806.23 3801.29 3494.6 138.56 136.45 134.96 128.73 126.56 134.98 136.6566667 130.09 4062.82 3898.16 4121.96 3700.706667 4027.646667 0.076749995 0.111306962 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0001764///neuron migration+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process 22152 22152 'Tubb3' mRNA 11 7 8 0.37 0.23 0.28 3.97 4.87 4.51 0.293333333 4.45 137 163.99 150.73 8.666666667 150.5733333 8.62E-27 4.104202128 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042277///peptide binding+++GO:1990890///netrin receptor binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0007411///axon guidance+++GO:0030182///neuron differentiation+++GO:0038007///netrin-activated signaling pathway+++GO:1990791///dorsal root ganglion development 22153 22153 'Tubb4a' mRNA 656 590 568 18.16 16.09 16.68 9.66 12.11 13.46 16.97666667 11.74333333 401 491 541 604.6666667 477.6666667 0.014529031 -0.348757257 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0030030///cell projection organization+++GO:0031115///negative regulation of microtubule polymerization 22154 22154 'Tubb5' mRNA 4067 4164 4101 85.27 85.94 91.21 281 276.68 284.41 87.47333333 280.6966667 15418 14825 15109 4110.666667 15117.33333 1.46E-276 1.866104341 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0045298///tubulin complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032794///GTPase activating protein binding+++GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0009987///cellular process+++GO:0050807///regulation of synapse organization+++GO:0051225///spindle assembly 22156 22156 'Tuft1' mRNA 2174 2173 1995 46.72 46.03 45.53 13.41 13.63 12.64 46.09333333 13.22666667 725 711 658 2114 698 7.37E-95 -1.609488452 GO:0005576///extracellular region+++GO:0005622///intracellular+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0031214///biomineral tissue development+++GO:0035556///intracellular signal transduction 22157 22157 'Tulp1' mRNA 14 8 11 0.38 0.21 0.32 0.35 0.07 0.15 0.303333333 0.19 15 3 6 11 8 0.660306665 -0.485389748 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043679///axon terminus+++GO:0045202///synapse "GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding" "GO:0001895///retina homeostasis+++GO:0006909///phagocytosis+++GO:0006910///phagocytosis, recognition+++GO:0007601///visual perception+++GO:0016192///vesicle-mediated transport+++GO:0016358///dendrite development+++GO:0042462///eye photoreceptor cell development+++GO:0045494///photoreceptor cell maintenance+++GO:0050766///positive regulation of phagocytosis+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060041///retina development in camera-type eye+++GO:0061512///protein localization to cilium+++GO:1903546///protein localization to photoreceptor outer segment" 22158 22158 'Tulp3' mRNA 1496 1519 1084 24.17 24.14 18.58 11.83 11.61 10.58 22.29666667 11.34 843 808 730 1366.333333 793.6666667 3.94E-13 -0.78914509 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0097546///ciliary base+++GO:0097731///9+0 non-motile cilium GO:0001664///G protein-coupled receptor binding+++GO:0019899///enzyme binding+++GO:0035091///phosphatidylinositol binding+++GO:0044877///protein-containing complex binding+++GO:0120160///intraciliary transport particle A binding GO:0001841///neural tube formation+++GO:0001843///neural tube closure+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009952///anterior/posterior pattern specification+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0021915///neural tube development+++GO:0021953///central nervous system neuron differentiation+++GO:0031076///embryonic camera-type eye development+++GO:0042733///embryonic digit morphogenesis+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0060173///limb development+++GO:0060348///bone development+++GO:0060434///bronchus morphogenesis+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0061512///protein localization to cilium+++GO:0061548///ganglion development+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 22160 22160 'Twist1' mRNA 25 29 25 0.9 1.02 0.95 1.47 1.95 1.58 0.956666667 1.666666667 47 61 49 26.33333333 52.33333333 0.017291555 0.982558908 05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001843///neural tube closure+++GO:0003180///aortic valve morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0003253///cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0030500///regulation of bone mineralization+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0032502///developmental process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033128///negative regulation of histone phosphorylation+++GO:0035067///negative regulation of histone acetylation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0042476///odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0044092///negative regulation of molecular function+++GO:0045596///negative regulation of cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060348///bone development+++GO:0060363///cranial suture morphogenesis+++GO:0060900///embryonic camera-type eye formation+++GO:0061029///eyelid development in camera-type eye+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0071363///cellular response to growth factor stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:2000147///positive regulation of cell motility+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2000773///negative regulation of cellular senescence+++GO:2000780///negative regulation of double-strand break repair+++GO:2000793///cell proliferation involved in heart valve development+++GO:2000802///positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation" 22163 22163 'Tnfrsf4' mRNA 27 9 14 1.42 0.45 0.77 0.93 0.87 0.58 0.88 0.793333333 20 19 13 16.66666667 17.33333333 0.96029257 0.045161411 04060///Cytokine-cytokine receptor interaction GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding "GO:0001818///negative regulation of cytokine production+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006954///inflammatory response+++GO:0006968///cellular defense response+++GO:0030890///positive regulation of B cell proliferation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042098///T cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045859///regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070236///negative regulation of activation-induced cell death of T cells+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 22165 22165 'Txk' mRNA 23 29 35 0.58 0.71 0.94 1.16 1.58 1.29 0.743333333 1.343333333 52 71 59 29 60.66666667 0.008566102 1.050202984 04670///Leukocyte transendothelial migration GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001819///positive regulation of cytokine production+++GO:0001865///NK T cell differentiation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007202///activation of phospholipase C activity+++GO:0007229///integrin-mediated signaling pathway+++GO:0010468///regulation of gene expression+++GO:0010543///regulation of platelet activation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032609///interferon-gamma production+++GO:0032633///interleukin-4 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042246///tissue regeneration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0050852///T cell receptor signaling pathway+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway 22166 22166 'Txn1' mRNA 1647 1543 1611 99.01 91.69 102.76 184.72 192.5 185.64 97.82 187.62 3524 3580 3423 1600.333333 3509 1.80E-56 1.120003859 04621///NOD-like receptor signaling pathway+++05012///Parkinson disease+++05132///Salmonella infection+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0047134///protein-disulfide reductase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006662///glycerol ether metabolic process+++GO:0009314///response to radiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0045454///cell redox homeostasis+++GO:0046826///negative regulation of protein export from nucleus+++GO:0071731///response to nitric oxide+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:2000170///positive regulation of peptidyl-cysteine S-nitrosylation 22169 22169 'Cmpk2' mRNA 374 446 481 6.42 7.53 8.75 14.1 14.41 13.53 7.566666667 14.01333333 946 944 879 433.6666667 923 1.25E-18 1.074293176 00240///Pyrimidine metabolism+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0004127///cytidylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0004798///thymidylate kinase activity+++GO:0005524///ATP binding+++GO:0009041///uridylate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033862///UMP kinase activity+++GO:0036430///CMP kinase activity+++GO:0036431///dCMP kinase activity+++GO:0050145///nucleoside monophosphate kinase activity GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006227///dUDP biosynthetic process+++GO:0006233///dTDP biosynthetic process+++GO:0006235///dTTP biosynthetic process+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0071222///cellular response to lipopolysaccharide 22171 22171 'Tyms' mRNA 545.75 591.15 549.2 6.17 6.7 6.65 8.05 8.27 7.9 6.506666667 8.073333333 748.04 753.88 714.93 562.0333333 738.95 3.37E-04 0.383227577 00240///Pyrimidine metabolism+++00670///One carbon pool by folate+++01523///Antifolate resistance GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003729///mRNA binding+++GO:0004799///thymidylate synthase activity+++GO:0005542///folic acid binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0016741///transferase activity, transferring one-carbon groups+++GO:0042803///protein homodimerization activity+++GO:1901363///heterocyclic compound binding+++GO:1990825///sequence-specific mRNA binding" GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006231///dTMP biosynthetic process+++GO:0006235///dTTP biosynthetic process+++GO:0006417///regulation of translation+++GO:0007568///aging+++GO:0007623///circadian rhythm+++GO:0009165///nucleotide biosynthetic process+++GO:0009636///response to toxic substance+++GO:0014070///response to organic cyclic compound+++GO:0017148///negative regulation of translation+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0019860///uracil metabolic process+++GO:0032259///methylation+++GO:0032570///response to progesterone+++GO:0033189///response to vitamin A+++GO:0034097///response to cytokine+++GO:0035999///tetrahydrofolate interconversion+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0046653///tetrahydrofolate metabolic process+++GO:0048589///developmental growth+++GO:0051216///cartilage development+++GO:0051384///response to glucocorticoid+++GO:0051593///response to folic acid+++GO:0060574///intestinal epithelial cell maturation+++GO:0097421///liver regeneration 22173 22173 'Tyr' mRNA 765.93 823.22 747.18 7.8 8.44 7.62 9.48 7.99 8.3 7.953333333 8.59 1058.84 950.06 980.38 778.7766667 996.4266667 2.51E-04 0.344043632 00350///Tyrosine metabolism+++04916///Melanogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004497///monooxygenase activity+++GO:0004503///monophenol monooxygenase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0008283///cell proliferation+++GO:0009411///response to UV+++GO:0009637///response to blue light+++GO:0033280///response to vitamin D+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0048538///thymus development+++GO:0051591///response to cAMP 22174 22174 'Tyro3' mRNA 1357 1400 1244 19.56 19.81 19.04 14.23 13.77 14.58 19.47 14.19333333 1134 1072 1132 1333.666667 1112.666667 9.49E-04 -0.271784805 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0001618///virus receptor activity+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043548///phosphatidylinositol 3-kinase binding GO:0001779///natural killer cell differentiation+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021885///forebrain cell migration+++GO:0030168///platelet activation+++GO:0032940///secretion by cell+++GO:0033674///positive regulation of kinase activity+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042698///ovulation cycle+++GO:0043277///apoptotic cell clearance+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045824///negative regulation of innate immune response+++GO:0046718///viral entry into host cell+++GO:0046777///protein autophosphorylation+++GO:0050728///negative regulation of inflammatory response+++GO:0051250///negative regulation of lymphocyte activation+++GO:0060068///vagina development+++GO:0070050///neuron cellular homeostasis+++GO:0070527///platelet aggregation+++GO:1903902///positive regulation of viral life cycle 22177 22177 'Tyrobp' mRNA 532 508 478 72.28 68.79 68.94 1021.61 1145.27 1061.25 70.00333333 1076.043333 8572 9336 8578 506 8828.666667 0 4.115218761 04380///Osteoclast differentiation+++04650///Natural killer cell mediated cytotoxicity GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0002222///stimulatory killer cell immunoglobulin-like receptor signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002274///myeloid leukocyte activation+++GO:0002281///macrophage activation involved in immune response+++GO:0002282///microglial cell activation involved in immune response+++GO:0002283///neutrophil activation involved in immune response+++GO:0002376///immune system process+++GO:0007229///integrin-mediated signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0030036///actin cytoskeleton organization+++GO:0030316///osteoclast differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0030900///forebrain development+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034241///positive regulation of macrophage fusion+++GO:0043277///apoptotic cell clearance+++GO:0048678///response to axon injury+++GO:0050821///protein stabilization+++GO:0097190///apoptotic signaling pathway+++GO:0110090///positive regulation of hippocampal neuron apoptotic process+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1901216///positive regulation of neuron death+++GO:1902685///positive regulation of receptor localization to synapse+++GO:1904151///positive regulation of microglial cell mediated cytotoxicity+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2001204///regulation of osteoclast development+++GO:2001206///positive regulation of osteoclast development 22178 22178 'Tyrp1' mRNA 189 201 229 3.81 3.98 4.9 9.03 9.7 10.15 4.23 9.626666667 516 541 561 206.3333333 539.3333333 2.17E-21 1.371737569 00350///Tyrosine metabolism+++04916///Melanogenesis GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030669///clathrin-coated endocytic vesicle membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0097708///intracellular vesicle GO:0004497///monooxygenase activity+++GO:0004503///monophenol monooxygenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006582///melanin metabolic process+++GO:0006583///melanin biosynthetic process from tyrosine+++GO:0030318///melanocyte differentiation+++GO:0032438///melanosome organization+++GO:0042438///melanin biosynthetic process+++GO:0043438///acetoacetic acid metabolic process+++GO:0043473///pigmentation+++GO:0048023///positive regulation of melanin biosynthetic process 22183 22183 'Zrsr1' mRNA 633.96 689.94 471.25 7.58 8.11 5.97 5.77 5.82 6 7.22 5.863333333 555.69 547.87 559.93 598.3833333 554.4966667 0.455630462 -0.115220522 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0089701///U2AF GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 22184 22184 'Zrsr2' mRNA 407 389 418 5.79 5.37 6.19 6.39 5.72 6.12 5.783333333 6.076666667 514 440 486.01 404.6666667 480.0033333 0.098208516 0.231654867 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0089701///U2AF GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 22185 22185 'U2af2' mRNA 1215 1274 729 30.38 31.03 19.03 22.63 18.79 19.91 26.81333333 20.44333333 1055 853 897 1072.666667 935 0.222273888 -0.200445786 03040///Spliceosome GO:0000243///commitment complex+++GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome+++GO:0089701///U2AF GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008187///poly-pyrimidine tract binding+++GO:0019899///enzyme binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0070742///C2H2 zinc finger domain binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033120///positive regulation of RNA splicing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 22186 22186 'Uba52' mRNA 3320.12 3108 3345.04 482.06 451.14 520.58 579.68 634.07 640.23 484.5933333 617.9933333 4507.83 4799.82 4814.13 3257.72 4707.26 2.30E-12 0.517800989 03010///Ribosome+++04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05171///Coronavirus disease - COVID-19 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding GO:0006412///translation+++GO:0016567///protein ubiquitination+++GO:0017085///response to insecticide+++GO:0019941///modification-dependent protein catabolic process 22187 22187 'Ubb' mRNA 51152.11 53226.93 50395.64 2441.04 2507.65 2547.41 2438.35 2674.23 2486.18 2498.7 2532.92 58838.15 63057.18 58107.31 51591.56 60000.88 3.26E-04 0.206866837 04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0021888///hypothalamus gonadotrophin-releasing hormone neuron development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0047497///mitochondrion transport along microtubule+++GO:0048812///neuron projection morphogenesis+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060612///adipose tissue development+++GO:0060613///fat pad development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072520///seminiferous tubule development+++GO:0097009///energy homeostasis+++GO:1901214///regulation of neuron death+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1902527///positive regulation of protein monoubiquitination 22190 22190 'Ubc' mRNA 30490.77 31305.07 30128.32 707.79 715.52 741.9 626.91 656.51 614.82 721.7366667 632.7466667 31061.02 31762 29490.56 30641.38667 30771.19333 0.938641229 -0.005706098 03320///PPAR signaling pathway+++04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043209///myelin sheath GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process 22192 22192 'Ube2m' mRNA 116 118 102 6.93 7.06 6.36 13.05 12.99 12.15 6.783333333 12.73 246 240 227 112 237.6666667 8.54E-09 1.075551139 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0019788///NEDD8 transferase activity GO:0006464///cellular protein modification process+++GO:0016567///protein ubiquitination+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045116///protein neddylation 22193 22193 'Ube2e3' mRNA 1835 1907 1135 67.37 69.8 44.3 40.45 46.09 43.82 60.49 43.45333333 1276 1402 1334 1625.666667 1337.333333 0.042622367 -0.281498347 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0040008///regulation of growth+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 22194 22194 'Ube2e1' mRNA 1497.76 1479.77 1235.29 64.66 63.04 56.58 58.1 57.98 59.5 61.42666667 58.52666667 1545.37 1504.48 1530.83 1404.273333 1526.893333 0.215623083 0.112334767 04120///Ubiquitin mediated proteolysis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0042296///ISG15 transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0010390///histone monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0032020///ISG15-protein conjugation+++GO:0033523///histone H2B ubiquitination+++GO:0070936///protein K48-linked ubiquitination 22195 22195 'Ube2l3' mRNA 3100.53 3072.15 3068.69 66.02 64.36 69.29 90.14 86.77 89.44 66.55666667 88.78333333 4871.85 4579 4679.86 3080.456667 4710.236667 1.51E-23 0.599776753 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0097027///ubiquitin-protein transferase activator activity "GO:0000209///protein polyubiquitination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0008283///cell proliferation+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0044770///cell cycle phase transition+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0070979///protein K11-linked ubiquitination+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071385///cellular response to glucocorticoid stimulus" 22196 22196 'Ube2i' mRNA 3424 3453 3322 74.19 73.86 77.02 95.13 96.72 92.71 75.02333333 94.85333333 5024 4991 4759 3399.666667 4924.666667 3.86E-19 0.522862573 03013///Nucleocytoplasmic transport+++04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++05206///MicroRNAs in cancer GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:1990234///transferase complex+++GO:1990356///sumoylated E2 ligase complex GO:0000166///nucleotide binding+++GO:0001221///transcription cofactor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019899///enzyme binding+++GO:0043398///HLH domain binding+++GO:0043425///bHLH transcription factor binding+++GO:0044388///small protein activating enzyme binding+++GO:0061656///SUMO conjugating enzyme activity+++GO:0071535///RING-like zinc finger domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006464///cellular protein modification process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:0016032///viral process+++GO:0016925///protein sumoylation+++GO:0033145///positive regulation of intracellular steroid hormone receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051301///cell division+++GO:1903755///positive regulation of SUMO transferase activity" 22200 22200 'Uba3' mRNA 1064 1062 1102 28.59 27.49 30.66 30.66 30.85 26.82 28.91333333 29.44333333 1337 1291 1192 1076 1273.333333 0.016069639 0.22923183 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity+++GO:0016922///nuclear receptor binding+++GO:0019781///NEDD8 activating enzyme activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity "GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007113///endomitotic cell cycle+++GO:0032446///protein modification by small protein conjugation+++GO:0045116///protein neddylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle" 22201 22201 'Uba1' mRNA 6728 6481 6816 88.84 84.2 95.52 86.22 82.93 80.33 89.52 83.16 7505.97 7049.01 6772 6675 7108.993333 0.316909822 0.076486192 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005765///lysosomal membrane+++GO:0010008///endosome membrane+++GO:0030057///desmosome+++GO:0030867///rough endoplasmic reticulum membrane GO:0000166///nucleotide binding+++GO:0004839///ubiquitin activating enzyme activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity GO:0006464///cellular protein modification process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0032446///protein modification by small protein conjugation 22202 22202 'Uba1y' mRNA 1 1 0 0.02 0.02 0 0.1 0.08 0.04 0.013333333 0.073333333 7 6 3 0.666666667 5.333333333 0.097303703 3.001381231 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004839///ubiquitin activating enzyme activity+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity GO:0006464///cellular protein modification process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0032446///protein modification by small protein conjugation 22209 22209 'Ube2a' mRNA 681 741 711 22.77 24.42 25.22 39.22 42.09 40.59 24.13666667 40.63333333 1348 1412 1350 711 1370 2.12E-25 0.934660214 04120///Ubiquitin mediated proteolysis GO:0000785///chromatin+++GO:0001741///XY body+++GO:0033503///HULC complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0001701///in utero embryonic development+++GO:0001835///blastocyst hatching+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0033522///histone H2A ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0060135///maternal process involved in female pregnancy+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 22210 22210 'Ube2b' mRNA 2997 3177 2951 90.39 95.67 95.63 85.3 89.47 87.35 93.89666667 87.37333333 3215 3305 3199 3041.666667 3239.666667 0.279633507 0.079997436 04120///Ubiquitin mediated proteolysis GO:0000785///chromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0033503///HULC complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0000237///leptotene+++GO:0001701///in utero embryonic development+++GO:0006281///DNA repair+++GO:0006301///postreplication repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0009410///response to xenobiotic stimulus+++GO:0009411///response to UV+++GO:0010845///positive regulation of reciprocal meiotic recombination+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0031056///regulation of histone modification+++GO:0033128///negative regulation of histone phosphorylation+++GO:0033522///histone H2A ubiquitination+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045141///meiotic telomere clustering+++GO:0050821///protein stabilization+++GO:0051026///chiasma assembly+++GO:0051865///protein autoubiquitination+++GO:0070076///histone lysine demethylation+++GO:0070193///synaptonemal complex organization+++GO:0070534///protein K63-linked ubiquitination+++GO:0070829///heterochromatin maintenance+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway 22213 22213 'Ube2g2' mRNA 1565 1542 1393 45 43.68 42.49 62.58 59.34 58.17 43.72333333 60.03 2502 2316 2251 1500 2356.333333 7.08E-20 0.640749504 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0061631///ubiquitin conjugating enzyme activity "GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0035458///cellular response to interferon-beta+++GO:0044257///cellular protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 22214 22214 'Ube2h' mRNA 1154 1185 1336 14.94 15.14 18.33 16.24 16.68 15.32 16.13666667 16.08 1447 1447 1323 1225 1405.666667 0.09516042 0.18265463 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 22215 22215 'Ube3a' mRNA 2231 2311 1328 17.09 17.59 8.83 7.88 10.13 9.99 14.50333333 9.333333333 1391 1524 1593.85 1956.666667 1502.95 0.141809261 -0.379235682 04120///Ubiquitin mediated proteolysis+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001541///ovarian follicle development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016567///protein ubiquitination+++GO:0030521///androgen receptor signaling pathway+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032570///response to progesterone+++GO:0035037///sperm entry+++GO:0035641///locomotory exploration behavior+++GO:0042220///response to cocaine+++GO:0042542///response to hydrogen peroxide+++GO:0042752///regulation of circadian rhythm+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050847///progesterone receptor signaling pathway+++GO:0051865///protein autoubiquitination+++GO:0060736///prostate gland growth+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0061743///motor learning+++GO:0070936///protein K48-linked ubiquitination+++GO:1905528///positive regulation of Golgi lumen acidification+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process 22217 22217 'Usp12' mRNA 301 300 263 3.89 3.86 3.7 3.35 3.21 3.87 3.816666667 3.476666667 293 281 330 288 301.3333333 0.788695373 0.05571956 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0101005///ubiquitinyl hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0050862///positive regulation of T cell receptor signaling pathway 22218 22218 'Sumo1' mRNA 2772 2923 3008 139.78 145.56 160.93 172.19 175.88 168.08 148.7566667 172.05 3919 3904 3699 2901 3840.666667 8.43E-08 0.390950586 03013///Nucleocytoplasmic transport+++05418///Fluid shear stress and atherosclerosis GO:0000792///heterochromatin+++GO:0001650///fibrillar center+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0045202///synapse+++GO:0097165///nuclear stress granule GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0015459///potassium channel regulator activity+++GO:0019899///enzyme binding+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding+++GO:0044388///small protein activating enzyme binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:1990381///ubiquitin-specific protease binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0010621///negative regulation of transcription by transcription factor localization+++GO:0016925///protein sumoylation+++GO:0030578///PML body organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031647///regulation of protein stability+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034605///cellular response to heat+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045759///negative regulation of action potential+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050821///protein stabilization+++GO:0060021///roof of mouth development+++GO:0071276///cellular response to cadmium ion+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0090204///protein localization to nuclear pore+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903169///regulation of calcium ion transmembrane transport" 22221 22221 'Ubp1' mRNA 600.03 626.03 556.04 9.45 9.64 9.35 9.4 8.65 8.73 9.48 8.926666667 677.37 612.36 622.19 594.0333333 637.3066667 0.486988988 0.089832311 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001525///angiogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032897///negative regulation of viral transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II 22222 22222 'Ubr1' mRNA 1134 1096 1069 7.72 7.34 7.7 6.39 5.21 6.3 7.586666667 5.966666667 1078 865 1034 1099.666667 992.3333333 0.132517626 -0.161426159 GO:0000151///ubiquitin ligase complex+++GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070728///leucine binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0032007///negative regulation of TOR signaling+++GO:0071233///cellular response to leucine+++GO:0071596///ubiquitin-dependent protein catabolic process via the N-end rule pathway 22223 22223 'Uchl1' mRNA 68 100 71 3.67 5.34 4.07 17.33 17.1 20.26 4.36 18.23 368 354 416 79.66666667 379.3333333 8.19E-33 2.243049868 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0044306///neuron projection terminus+++GO:1904115///axon cytoplasm GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008242///omega peptidase activity+++GO:0016787///hydrolase activity+++GO:0016874///ligase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0043130///ubiquitin binding GO:0002931///response to ischemia+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007409///axonogenesis+++GO:0007412///axon target recognition+++GO:0007628///adult walking behavior+++GO:0008283///cell proliferation+++GO:0016579///protein deubiquitination+++GO:0019233///sensory perception of pain+++GO:0019896///axonal transport of mitochondrion+++GO:0035690///cellular response to drug+++GO:0042755///eating behavior+++GO:0043407///negative regulation of MAP kinase activity+++GO:0048747///muscle fiber development+++GO:0050905///neuromuscular process+++GO:0055001///muscle cell development+++GO:0071466///cellular response to xenobiotic stimulus 22224 22224 'Usp10' mRNA 1513 1616 1549 21.98 23.5 24.02 19.37 19.45 18.13 23.16666667 18.98333333 1523 1500 1377 1559.333333 1466.666667 0.284425031 -0.10069559 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0045111///intermediate filament cytoskeleton GO:0002039///p53 binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0044325///ion channel binding "GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010506///regulation of autophagy+++GO:0016579///protein deubiquitination+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0071347///cellular response to interleukin-1" 22225 22225 'Usp5' mRNA 2254 2452 2253 39.18 41.98 41.57 44.83 45.73 44.26 40.91 44.94 2967 2955 2837 2319.666667 2919.666667 1.94E-06 0.320621456 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0071108///protein K48-linked deubiquitination 22227 22227 'Ucp1' mRNA 2 2 2 0.07 0.07 0.08 0.12 0.03 0.1 0.073333333 0.083333333 4 1 3 2 2.666666667 0.863090843 0.394750616 03320///PPAR signaling pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++05016///Huntington disease GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0017077///oxidative phosphorylation uncoupler activity+++GO:0019003///GDP binding+++GO:0022857///transmembrane transporter activity+++GO:0032555///purine ribonucleotide binding+++GO:0036041///long-chain fatty acid binding+++GO:1901612///cardiolipin binding GO:0002024///diet induced thermogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006811///ion transport+++GO:0006839///mitochondrial transport+++GO:0009266///response to temperature stimulus+++GO:0009409///response to cold+++GO:0031667///response to nutrient levels+++GO:0032870///cellular response to hormone stimulus+++GO:0034614///cellular response to reactive oxygen species+++GO:0050873///brown fat cell differentiation+++GO:0070417///cellular response to cold+++GO:0071398///cellular response to fatty acid+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1902600///proton transmembrane transport+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1990542///mitochondrial transmembrane transport+++GO:1990845///adaptive thermogenesis 22228 22228 'Ucp2' mRNA 6268 6106 6026 232.53 223.87 237.43 561.02 524.16 551.17 231.2766667 545.45 17377 15835 16503 6133.333333 16571.66667 5.68E-166 1.421102706 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0017077///oxidative phosphorylation uncoupler activity GO:0000303///response to superoxide+++GO:0001666///response to hypoxia+++GO:0006839///mitochondrial transport+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0009409///response to cold+++GO:0009749///response to glucose+++GO:0010942///positive regulation of cell death+++GO:0032869///cellular response to insulin stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0034198///cellular response to amino acid starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070542///response to fatty acid+++GO:0071333///cellular response to glucose stimulus+++GO:0097421///liver regeneration+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1902600///proton transmembrane transport+++GO:1990542///mitochondrial transmembrane transport+++GO:1990845///adaptive thermogenesis 22229 22229 'Ucp3' mRNA 116 80 79 2.64 1.8 1.91 0.2 0.3 0.53 2.116666667 0.343333333 10 15 26 91.66666667 17 1.34E-09 -2.436945231 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0017077///oxidative phosphorylation uncoupler activity GO:0000303///response to superoxide+++GO:0001666///response to hypoxia+++GO:0006631///fatty acid metabolic process+++GO:0006839///mitochondrial transport+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009409///response to cold+++GO:0014823///response to activity+++GO:0032868///response to insulin+++GO:0032870///cellular response to hormone stimulus+++GO:0048545///response to steroid hormone+++GO:0051384///response to glucocorticoid+++GO:1902600///proton transmembrane transport+++GO:1990542///mitochondrial transmembrane transport+++GO:1990845///adaptive thermogenesis 22230 22230 'Ufd1' mRNA 1567 1641 1497 44.06 45.36 44.66 38.1 36.52 37.21 44.69333333 37.27666667 1552 1452 1470 1568.333333 1491.333333 0.334125461 -0.083917184 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0036501///UFD1-NPL4 complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0044877///protein-containing complex binding+++GO:0051117///ATPase binding "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0032480///negative regulation of type I interferon production+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0071712///ER-associated misfolded protein catabolic process" 22232 22232 'Slc35a2' mRNA 824 885 691 23.57 25.2 21.31 22.34 21.19 21.7 23.36 21.74333333 870 805 797 800 824 0.809903856 0.034306837 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0005459///UDP-galactose transmembrane transporter activity+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0008643///carbohydrate transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport 22234 22234 'Ugcg' mRNA 449 433 399 6.54 6.2 6.17 8.86 7.43 8.01 6.303333333 8.1 700 573 613 427 628.6666667 4.41E-06 0.546012166 00600///Sphingolipid metabolism GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008120///ceramide glucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0102769///dihydroceramide glucosyltransferase activity" GO:0006497///protein lipidation+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006679///glucosylceramide biosynthetic process+++GO:0009966///regulation of signal transduction+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0033210///leptin-mediated signaling pathway+++GO:0048666///neuron development+++GO:0061436///establishment of skin barrier+++GO:0098856///intestinal lipid absorption+++GO:1903575///cornified envelope assembly 22235 22235 'Ugdh' mRNA 3570 3894 3450 82.99 88.75 85.17 36.85 35.14 37.55 85.63666667 36.51333333 1822 1683 1788 3638 1764.333333 6.26E-61 -1.054981414 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0003979///UDP-glucose 6-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042802///identical protein binding+++GO:0051287///NAD binding" GO:0001702///gastrulation with mouth forming second+++GO:0005975///carbohydrate metabolic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006065///UDP-glucuronate biosynthetic process+++GO:0008152///metabolic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0034214///protein hexamerization+++GO:0048666///neuron development 22238 22238 'Ugt2b5' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++00860///Porphyrin metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005640///nuclear outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008210///estrogen metabolic process+++GO:0052695///cellular glucuronidation 22239 22239 'Ugt8a' mRNA 1396 1341 1350 18.58 17.19 18.84 12.18 10.5 11.81 18.20333333 11.49666667 1053 889 969 1362.333333 970.3333333 1.52E-08 -0.503176043 00565///Ether lipid metabolism+++00600///Sphingolipid metabolism GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003851///2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity+++GO:0008120///ceramide glucosyltransferase activity+++GO:0008194///UDP-glycosyltransferase activity+++GO:0008489///UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047263///N-acylsphingosine galactosyltransferase activity" GO:0002175///protein localization to paranode region of axon+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006682///galactosylceramide biosynthetic process+++GO:0007010///cytoskeleton organization+++GO:0009247///glycolipid biosynthetic process+++GO:0030913///paranodal junction assembly+++GO:0042552///myelination+++GO:0048812///neuron projection morphogenesis 22240 22240 'Dpysl3' mRNA 845 886 691 8.28 8.53 7.2 15.76 14.59 16.08 8.003333333 15.47666667 1847 1671 1824 807.3333333 1780.666667 3.28E-39 1.132873327 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0070382///exocytic vesicle "GO:0004157///dihydropyrimidinase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0017124///SH3 domain binding+++GO:0031005///filamin binding+++GO:0035374///chondroitin sulfate binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding" GO:0006208///pyrimidine nucleobase catabolic process+++GO:0007399///nervous system development+++GO:0010975///regulation of neuron projection development+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0048666///neuron development+++GO:0048678///response to axon injury+++GO:0051017///actin filament bundle assembly+++GO:0051491///positive regulation of filopodium assembly+++GO:0051764///actin crosslink formation+++GO:0071345///cellular response to cytokine stimulus 22241 22241 'Ulk1' mRNA 787 755 764 9.22 8.75 9.64 8.75 7.65 9.32 9.203333333 8.573333333 844 730 881 768.6666667 818.3333333 0.561348178 0.077124168 04137///Mitophagy - animal+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0034045///phagophore assembly site membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097629///extrinsic component of omegasome membrane+++GO:0097632///extrinsic component of phagophore assembly site membrane+++GO:0097635///extrinsic component of autophagosome membrane+++GO:1990316///Atg1/ULK1 kinase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding+++GO:0051879///Hsp90 protein binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0000423///mitophagy+++GO:0006468///protein phosphorylation+++GO:0006914///autophagy+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007409///axonogenesis+++GO:0008104///protein localization+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010941///regulation of cell death+++GO:0016236///macroautophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021707///cerebellar granule cell differentiation+++GO:0021933///radial glia guided migration of cerebellar granule cell+++GO:0031102///neuron projection regeneration+++GO:0031175///neuron projection development+++GO:0031333///negative regulation of protein complex assembly+++GO:0031623///receptor internalization+++GO:0031669///cellular response to nutrient levels+++GO:0034198///cellular response to amino acid starvation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0042594///response to starvation+++GO:0044805///late nucleophagy+++GO:0046777///protein autophosphorylation+++GO:0048671///negative regulation of collateral sprouting+++GO:0048675///axon extension+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0061709///reticulophagy+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:0098780///response to mitochondrial depolarisation+++GO:2000786///positive regulation of autophagosome assembly 22242 22242 'Umod' mRNA 1 0 0 0.02 0 0 0 0.02 0 0.006666667 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0000922///spindle pole+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0060170///ciliary membrane GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019864///IgG binding GO:0000255///allantoin metabolic process+++GO:0001822///kidney development+++GO:0002251///organ or tissue specific immune response+++GO:0003091///renal water homeostasis+++GO:0003094///glomerular filtration+++GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0006883///cellular sodium ion homeostasis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006986///response to unfolded protein+++GO:0007029///endoplasmic reticulum organization+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007588///excretion+++GO:0008217///regulation of blood pressure+++GO:0008380///RNA splicing+++GO:0009410///response to xenobiotic stimulus+++GO:0009414///response to water deprivation+++GO:0010467///gene expression+++GO:0015747///urate transport+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019628///urate catabolic process+++GO:0030104///water homeostasis+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030643///cellular phosphate ion homeostasis+++GO:0030644///cellular chloride ion homeostasis+++GO:0032496///response to lipopolysaccharide+++GO:0032602///chemokine production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0033554///cellular response to stress+++GO:0033555///multicellular organismal response to stress+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035809///regulation of urine volume+++GO:0036270///response to diuretic+++GO:0042493///response to drug+++GO:0044861///protein transport into plasma membrane raft+++GO:0046720///citric acid secretion+++GO:0048871///multicellular organismal homeostasis+++GO:0048878///chemical homeostasis+++GO:0050801///ion homeostasis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051223///regulation of protein transport+++GO:0055062///phosphate ion homeostasis+++GO:0055064///chloride ion homeostasis+++GO:0055074///calcium ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0060073///micturition+++GO:0061077///chaperone-mediated protein folding+++GO:0070294///renal sodium ion absorption+++GO:0072044///collecting duct development+++GO:0072051///juxtaglomerular apparatus development+++GO:0072070///loop of Henle development+++GO:0072218///metanephric ascending thin limb development+++GO:0072221///metanephric distal convoluted tubule development+++GO:0072233///metanephric thick ascending limb development+++GO:0072665///protein localization to vacuole+++GO:0097190///apoptotic signaling pathway+++GO:0097273///creatinine homeostasis+++GO:0097709///connective tissue replacement+++GO:0097744///urate salt excretion+++GO:1990266///neutrophil migration 22245 22245 'Uck1' mRNA 1898 1935 1938 55.51 55.78 60.13 48.07 50.61 47.37 57.14 48.68333333 1891 1942 1802 1923.666667 1878.333333 0.641401553 -0.046938452 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004849///uridine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019206///nucleoside kinase activity GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0044206///UMP salvage+++GO:0044211///CTP salvage 22247 22247 'Umps' mRNA 318 333 276 4.97 5.13 4.57 7.99 8.15 9.08 4.89 8.406666667 588 586 646 309 606.6666667 4.32E-15 0.964604319 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0003824///catalytic activity+++GO:0004588///orotate phosphoribosyltransferase activity+++GO:0004590///orotidine-5'-phosphate decarboxylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0042802///identical protein binding" GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006222///UMP biosynthetic process+++GO:0006225///UDP biosynthetic process+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0009116///nucleoside metabolic process+++GO:0019856///pyrimidine nucleobase biosynthetic process+++GO:0035690///cellular response to drug+++GO:0044205///'de novo' UMP biosynthetic process 22248 22248 'Unc119' mRNA 109 97 60 6.15 5.52 3.63 4.13 4.29 5.11 5.1 4.51 84 82 99 88.66666667 88.33333333 0.991284858 -0.007532418 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0045171///intercellular bridge+++GO:0051233///spindle midzone GO:0005515///protein binding+++GO:0008289///lipid binding GO:0000281///mitotic cytokinesis+++GO:0006897///endocytosis+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0015031///protein transport+++GO:0042953///lipoprotein transport+++GO:0050896///response to stimulus+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:2001287///negative regulation of caveolin-mediated endocytosis 22249 22249 'Unc13b' mRNA 866.29 894.74 705.48 6.33 6.5 5.35 3.54 3.86 3.87 6.06 3.756666667 603.06 608.34 612.44 822.17 607.9466667 3.34E-05 -0.442651201 04721///Synaptic vesicle cycle GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0032009///early phagosome+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0097470///ribbon synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0001566///non-kinase phorbol ester receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0017075///syntaxin-1 binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0019992///diacylglycerol binding+++GO:0030507///spectrin binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding "GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007528///neuromuscular junction development+++GO:0010807///regulation of synaptic vesicle priming+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0030154///cell differentiation+++GO:0031914///negative regulation of synaptic plasticity+++GO:0031915///positive regulation of synaptic plasticity+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0045921///positive regulation of exocytosis+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050435///amyloid-beta metabolic process+++GO:0050714///positive regulation of protein secretion+++GO:0060291///long-term synaptic potentiation+++GO:0060384///innervation+++GO:0060478///acrosomal vesicle exocytosis+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0061789///dense core granule priming+++GO:0061790///dense core granule docking+++GO:0071333///cellular response to glucose stimulus+++GO:0090382///phagosome maturation+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0099011///neuronal dense core vesicle exocytosis+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:1900426///positive regulation of defense response to bacterium+++GO:1900451///positive regulation of glutamate receptor signaling pathway+++GO:1902991///regulation of amyloid precursor protein catabolic process+++GO:1903861///positive regulation of dendrite extension" 22253 22253 'Unc5c' mRNA 182.43 195.39 154.93 1.02 1.08 0.92 0.65 0.74 0.8 1.006666667 0.73 131.84 148 159.2 177.5833333 146.3466667 0.2060273 -0.284584527 04360///Axon guidance GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0005042///netrin receptor activity+++GO:0005043///netrin receptor activity involved in chemorepulsion+++GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0019901///protein kinase binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0030334///regulation of cell migration+++GO:0033564///anterior/posterior axon guidance+++GO:0038007///netrin-activated signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0061643///chemorepulsion of axon+++GO:1990791///dorsal root ganglion development 22255 22255 'Uncx' mRNA 4 6 0 0.11 0.16 0 0.02 0 0.02 0.09 0.013333333 1 0 1 3.333333333 0.666666667 0.328149453 -2.304615816 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001502///cartilage condensation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0021516///dorsal spinal cord development+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0030154///cell differentiation+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0045595///regulation of cell differentiation" 22256 22256 'Ung' mRNA 184 189 193.75 5.53 5.62 6.18 10 9.99 10.31 5.776666667 10.1 382 373.17 381 188.9166667 378.7233333 3.03E-11 0.99233067 03410///Base excision repair+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0003684///damaged DNA binding+++GO:0004844///uracil DNA N-glycosylase activity+++GO:0016787///hydrolase activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0043024///ribosomal small subunit binding+++GO:0045437///uridine nucleosidase activity" "GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0043066///negative regulation of apoptotic process+++GO:0045190///isotype switching+++GO:0097510///base-excision repair, AP site formation via deaminated base removal" 22258 22258 'Usp4' mRNA 2359.01 2488.07 2498.96 34.39 35.85 39.05 33.69 34.12 31.63 36.43 33.14666667 2638 2612 2388 2448.68 2546 0.670096613 0.04307167 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031685///adenosine receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0034394///protein localization to cell surface 22259 22259 'Nr1h3' mRNA 258 244 259 8.6 7.88 9.13 14.45 15.42 17.48 8.536666667 15.78333333 512 527 591 253.6666667 543.3333333 1.05E-15 1.086591643 03320///PPAR signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++05160///Hepatitis C GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0032810///sterol response element binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0032570///response to progesterone+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0042632///cholesterol homeostasis+++GO:0043031///negative regulation of macrophage activation+++GO:0043277///apoptotic cell clearance+++GO:0044255///cellular lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045861///negative regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048550///negative regulation of pinocytosis+++GO:0050728///negative regulation of inflammatory response+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0055088///lipid homeostasis+++GO:0055092///sterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1903573///negative regulation of response to endoplasmic reticulum stress" 22260 22260 'Nr1h2' mRNA 3138.41 3265.06 2996.34 86.92 89.22 88.32 67.54 69.18 65.51 88.15333333 67.41 2787.98 2780.63 2622.93 3133.27 2730.513333 0.001320393 -0.209734842 04931///Insulin resistance GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0051117///ATPase binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010884///positive regulation of lipid storage+++GO:0010887///negative regulation of cholesterol storage+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0031667///response to nutrient levels+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0042632///cholesterol homeostasis+++GO:0044255///cellular lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045861///negative regulation of proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048550///negative regulation of pinocytosis+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0055088///lipid homeostasis+++GO:0090108///positive regulation of high-density lipoprotein particle assembly+++GO:0090187///positive regulation of pancreatic juice secretion+++GO:0090340///positive regulation of secretion of lysosomal enzymes+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1903573///negative regulation of response to endoplasmic reticulum stress" 22268 22268 'Upk1b' mRNA 17 6 1 0.56 0.19 0.03 0.34 0.32 0.76 0.26 0.473333333 12 11 26 8 16.33333333 0.288526528 1.042160691 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0120001///apical plasma membrane urothelial plaque GO:0009617///response to bacterium+++GO:0030855///epithelial cell differentiation 22269 22269 'Upk2' mRNA 7 4 4 0.53 0.3 0.32 1.26 1.22 1.58 0.383333333 1.353333333 19 18 23 5 20 0.008920631 1.991512516 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0120001///apical plasma membrane urothelial plaque GO:0030855///epithelial cell differentiation 22270 22270 'Upk3a' mRNA 2 3 3 0.11 0.17 0.18 0.34 0.15 0.15 0.153333333 0.213333333 7 3 3 2.666666667 4.333333333 0.689442381 0.67781499 05219///Bladder cancer GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0120001///apical plasma membrane urothelial plaque GO:0000902///cell morphogenesis+++GO:0001822///kidney development+++GO:0006833///water transport+++GO:0015840///urea transport+++GO:0030855///epithelial cell differentiation+++GO:0055075///potassium ion homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0060157///urinary bladder development 22271 22271 'Upp1' mRNA 362 431 400 17.56 20.58 20.56 18.7 17.59 16.21 19.56666667 17.5 443 407 372 397.6666667 407.3333333 0.903667124 0.021677018 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0004850///uridine phosphorylase activity+++GO:0009032///thymidine phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042802///identical protein binding+++GO:0047847///deoxyuridine phosphorylase activity" GO:0006218///uridine catabolic process+++GO:0006220///pyrimidine nucleotide metabolic process+++GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0009116///nucleoside metabolic process+++GO:0009166///nucleotide catabolic process+++GO:0042149///cellular response to glucose starvation+++GO:0044206///UMP salvage+++GO:0046050///UMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process+++GO:0046108///uridine metabolic process 22272 22272 'Uqcrq' mRNA 1596 1552 1765 61.79 59.32 72.48 80.43 95.92 86.53 64.53 87.62666667 2386 2776 2483 1637.666667 2548.333333 9.46E-11 0.623831751 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0005515///protein binding+++GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0044877///protein-containing complex binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0021539///subthalamus development+++GO:0021548///pons development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021766///hippocampus development+++GO:0021794///thalamus development+++GO:0021854///hypothalamus development+++GO:0021860///pyramidal neuron development+++GO:0030901///midbrain development" 22273 22273 'Uqcrc1' mRNA 6850 6953 6770 240.99 241.16 252.68 246.25 267.7 245.45 244.9433333 253.1333333 8043 8533 7757 6857.666667 8111 2.87E-04 0.230560627 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0014823///response to activity+++GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0043279///response to alkaloid" 22275 22275 'Urod' mRNA 1576.12 1634.52 1562.03 64.3 65.61 67.44 60.36 56.87 57.13 65.78333333 58.12 1690.97 1560 1535.33 1590.89 1595.433333 0.934509941 -0.008539747 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004853///uroporphyrinogen decarboxylase activity+++GO:0008198///ferrous iron binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0042168///heme metabolic process+++GO:0046502///uroporphyrinogen III metabolic process 22276 22276 'Uros' mRNA 991.93 1016.44 1003.8 28.55 30.2 32.12 23.29 22.92 23.99 30.29 23.4 908.64 847.99 921.08 1004.056667 892.57 0.065794193 -0.1824122 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004852///uroporphyrinogen-III synthase activity+++GO:0005542///folic acid binding+++GO:0016829///lyase activity GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006780///uroporphyrinogen III biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0046677///response to antibiotic+++GO:0070541///response to platinum ion+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071418///cellular response to amine stimulus 22278 22278 'Usf1' mRNA 1201 1309 1095 38.43 41.27 37.42 39.37 38.05 37.14 39.04 38.18666667 1407 1331 1290 1201.666667 1342.666667 0.095613437 0.150355768 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000432///positive regulation of transcription from RNA polymerase II promoter by glucose+++GO:0001666///response to hypoxia+++GO:0006006///glucose metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009411///response to UV+++GO:0019086///late viral transcription+++GO:0032869///cellular response to insulin stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055088///lipid homeostasis" 22282 22282 'Usf2' mRNA 685 670 640 15.87 15.24 15.76 13.08 11.6 12.51 15.62333333 12.39666667 644 558 589 665 597 0.154129909 -0.167956158 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000432///positive regulation of transcription from RNA polymerase II promoter by glucose+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007595///lactation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055088///lipid homeostasis" 22283 22283 'Ush2a' mRNA 2603 2752 2426 8.63 8.98 8.52 0.87 0.66 0.91 8.71 0.813333333 305 226 308 2593.666667 279.6666667 2.53E-237 -3.224720744 GO:0001917///photoreceptor inner segment+++GO:0002141///stereocilia ankle link+++GO:0002142///stereocilia ankle link complex+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0060171///stereocilium membrane+++GO:1990075///periciliary membrane compartment+++GO:1990696///USH2 complex GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0017022///myosin binding+++GO:0042802///identical protein binding GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035315///hair cell differentiation+++GO:0045184///establishment of protein localization+++GO:0045494///photoreceptor cell maintenance+++GO:0048496///maintenance of animal organ identity+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus+++GO:0060113///inner ear receptor cell differentiation 22284 22284 'Usp9x' mRNA 2339 2461 2434 10.02 10.39 11.16 9.41 7.82 9.04 10.52333333 8.756666667 2500 2036 2332 2411.333333 2289.333333 0.351072426 -0.089399883 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0045177///apical part of cell GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0070410///co-SMAD binding+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0009791///post-embryonic development+++GO:0016477///cell migration+++GO:0016579///protein deubiquitination+++GO:0021698///cerebellar cortex structural organization+++GO:0021766///hippocampus development+++GO:0030509///BMP signaling pathway+++GO:0042752///regulation of circadian rhythm+++GO:0048511///rhythmic process+++GO:0048675///axon extension+++GO:0050821///protein stabilization+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0051301///cell division+++GO:0071108///protein K48-linked deubiquitination+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:1901537///positive regulation of DNA demethylation+++GO:1990138///neuron projection extension 22288 22288 'Utrn' mRNA 5347 5628 4852 21.7 22.3 21.05 14.16 12.19 13.85 21.68333333 13.4 3996 3405 3813 5275.666667 3738 1.73E-15 -0.507808202 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031527///filopodium membrane+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0070938///contractile ring GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0017166///vinculin binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0001954///positive regulation of cell-matrix adhesion+++GO:0007527///adult somatic muscle development+++GO:0007528///neuromuscular junction development+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0030036///actin cytoskeleton organization+++GO:2000649///regulation of sodium ion transmembrane transporter activity 22289 22289 'Kdm6a' mRNA 775 749 783 6.68 6.44 7.27 5.1 4.85 4.63 6.796666667 4.86 673 617 587 769 625.6666667 0.004943131 -0.31157867 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0071558///histone demethylase activity (H3-K27 specific) GO:0001701///in utero embryonic development+++GO:0001843///neural tube closure+++GO:0003007///heart morphogenesis+++GO:0003016///respiratory system process+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0021915///neural tube development+++GO:0032525///somite rostral/caudal axis specification+++GO:0035264///multicellular organism growth+++GO:0048333///mesodermal cell differentiation+++GO:0048568///embryonic organ development+++GO:0048570///notochord morphogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0071557///histone H3-K27 demethylation+++GO:0072359///circulatory system development 22290 22290 'Uty' mRNA 420.72 440.65 410.51 4.43 4.56 4.62 3.59 3.39 3.48 4.536666667 3.486666667 393.77 355.84 367.22 423.96 372.2766667 0.156558144 -0.199744549 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0044666///MLL3/4 complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)+++GO:0071558///histone demethylase activity (H3-K27 specific) GO:0001701///in utero embryonic development+++GO:0003007///heart morphogenesis+++GO:0006325///chromatin organization+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0031507///heterochromatin assembly+++GO:0031935///regulation of chromatin silencing+++GO:0045184///establishment of protein localization+++GO:0048568///embryonic organ development+++GO:0060070///canonical Wnt signaling pathway+++GO:0070544///histone H3-K36 demethylation+++GO:0071557///histone H3-K27 demethylation+++GO:0086003///cardiac muscle cell contraction 22293 22293 'Slc45a2' mRNA 772 787 790 14.22 14.27 15.44 23.15 22.26 20.95 14.64333333 22.12 1446 1358 1267 783 1357 4.02E-18 0.780085075 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane GO:0008506///sucrose:proton symporter activity+++GO:0022857///transmembrane transporter activity GO:0007601///visual perception+++GO:0015770///sucrose transport+++GO:0042438///melanin biosynthetic process+++GO:0048066///developmental pigmentation+++GO:0050896///response to stimulus+++GO:0055085///transmembrane transport 22294 22294 'Uxt' mRNA 338 296 323 30.49 26.99 30.98 31.28 31.19 32.57 29.48666667 31.68 391 394 398 319 394.3333333 0.048851434 0.292988658 GO:0000785///chromatin+++GO:0000922///spindle pole+++GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0048487///beta-tubulin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000226///microtubule cytoskeleton organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007098///centrosome cycle 22295 22295 'Cdh23' mRNA 1186 1114 1048 6.71 6.36 6.29 0.52 0.42 0.73 6.453333333 0.556666667 103 95 117 1116 105 2.30E-155 -3.420697808 GO:0001917///photoreceptor inner segment+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0060091///kinocilium+++GO:0098683///cochlear hair cell ribbon synapse+++GO:0098684///photoreceptor ribbon synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0006816///calcium ion transport+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0008344///adult locomotory behavior+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0048839///inner ear development+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060013///righting reflex+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 22297 22297 'Vmn1r45' mRNA 2 0 0 0.03 0 0 0 0.01 0 0.01 0.003333333 0 1 0 0.666666667 0.333333333 0.863090843 -0.883181564 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 22306 22306 'Vmn2r30' mRNA 3.64 4 4 0.05 0.06 0.06 0.02 0 0.01 0.056666667 0.01 1.83 0 1 3.88 0.943333333 0.224406081 -2.480248054 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 22307 22307 'Vmn2r10' mRNA 0 0 1 0 0 0.01 0.01 0.01 0 0.003333333 0.006666667 1 1 0 0.333333333 0.666666667 0.863090843 0.881266102 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 22310 22310 'Vmn2r42' mRNA 0 0 1 0 0 0.02 0 0.01 0 0.006666667 0.003333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 22317 22317 'Vamp1' mRNA 1294 1255 1160 22.51 21.55 21.36 13.22 12.53 12.94 21.80666667 12.89666667 868 805 831 1236.333333 834.6666667 8.68E-12 -0.577791953 04130///SNARE interactions in vesicular transport GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0035579///specific granule membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0070821///tertiary granule membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding GO:0006906///vesicle fusion+++GO:0016082///synaptic vesicle priming+++GO:0016192///vesicle-mediated transport+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0035493///SNARE complex assembly 22318 22318 'Vamp2' mRNA 6428 6413 5382 167.73 164.81 148.98 76.22 76.51 71.81 160.5066667 74.84666667 3359 3292 3063 6074.333333 3238 9.82E-48 -0.916203905 04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle+++04911///Insulin secretion+++04962///Vasopressin-regulated water reabsorption+++04970///Salivary secretion GO:0000322///storage vacuole+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0042589///zymogen granule membrane+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044306///neuron projection terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0070032///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex+++GO:0070033///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0008022///protein C-terminus binding+++GO:0017022///myosin binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0048306///calcium-dependent protein binding GO:0006906///vesicle fusion+++GO:0009749///response to glucose+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017157///regulation of exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0032869///cellular response to insulin stimulus+++GO:0035493///SNARE complex assembly+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0043308///eosinophil degranulation+++GO:0045055///regulated exocytosis+++GO:0046879///hormone secretion+++GO:0048488///synaptic vesicle endocytosis+++GO:0060291///long-term synaptic potentiation+++GO:0060627///regulation of vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0065003///protein-containing complex assembly+++GO:0090316///positive regulation of intracellular protein transport+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:1903421///regulation of synaptic vesicle recycling 22319 22319 'Vamp3' mRNA 1413.92 1471 1552 37.84 38.77 44.06 62.09 59.83 61.65 40.22333333 61.19 2668 2510 2564 1478.973333 2580.666667 8.27E-24 0.78889293 04130///SNARE interactions in vesicular transport+++04145///Phagosome GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097708///intracellular vesicle GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding "GO:0001921///positive regulation of receptor recycling+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035493///SNARE complex assembly+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0065003///protein-containing complex assembly+++GO:0071346///cellular response to interferon-gamma+++GO:1903531///negative regulation of secretion by cell" 22320 22320 'Vamp8' mRNA 4357 4349 4392 379.82 375.88 406.32 470.08 505.95 468.47 387.34 481.5 6171 6467 5937 4366 6191.666667 3.94E-14 0.491570384 04130///SNARE interactions in vesicular transport+++04140///Autophagy - animal+++04611///Platelet activation GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030141///secretory granule+++GO:0030496///midbody+++GO:0030667///secretory granule membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0035577///azurophil granule membrane+++GO:0042588///zymogen granule+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0098594///mucin granule GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019869///chloride channel inhibitor activity+++GO:0019905///syntaxin binding GO:0006906///vesicle fusion+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016240///autophagosome membrane docking+++GO:0030100///regulation of endocytosis+++GO:0035493///SNARE complex assembly+++GO:0046718///viral entry into host cell+++GO:0051607///defense response to virus+++GO:0061025///membrane fusion+++GO:0065003///protein-containing complex assembly+++GO:0070254///mucus secretion+++GO:0070625///zymogen granule exocytosis+++GO:0071346///cellular response to interferon-gamma+++GO:0097352///autophagosome maturation+++GO:1902278///positive regulation of pancreatic amylase secretion+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903531///negative regulation of secretion by cell+++GO:1903595///positive regulation of histamine secretion by mast cell 22321 22321 'Vars' mRNA 1421.53 1501.87 1430.2 18.48 19.26 19.64 20.28 20.7 22.02 19.12666667 21 1794.83 1789.58 1883.58 1451.2 1822.663333 4.63E-05 0.317193258 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004832///valine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006438///valyl-tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 223227 223227 'Sox21' mRNA 572 552 176 8.15 7.74 2.66 0.98 0.79 1.1 6.183333333 0.956666667 79 62 86 433.3333333 75.66666667 1.65E-06 -2.50802389 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0001942///hair follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0042633///hair cycle+++GO:0043588///skin development+++GO:0045665///negative regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation" 22323 22323 'Vasp' mRNA 514 476 266 12.84 11.71 7.05 22.18 20.73 23.68 10.53333333 22.19666667 1021 932 1055 418.6666667 1002.666667 1.18E-15 1.259555173 04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031258///lamellipodium membrane+++GO:0031527///filopodium membrane+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0017124///SH3 domain binding GO:0001843///neural tube closure+++GO:0007411///axon guidance+++GO:0008154///actin polymerization or depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051289///protein homotetramerization 22324 22324 'Vav1' mRNA 93.03 89.01 113.02 1.2 1.14 1.55 13.8 13.63 13.23 1.296666667 13.55333333 1226.83 1185.39 1139.01 98.35333333 1183.743333 1.92E-159 3.574699636 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis GO:0005829///cytosol+++GO:0005911///cell-cell junction GO:0001784///phosphotyrosine residue binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0140031///phosphorylation-dependent protein binding GO:0006909///phagocytosis+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0030217///T cell differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0035556///intracellular signal transduction+++GO:0042110///T cell activation+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050790///regulation of catalytic activity+++GO:0072593///reactive oxygen species metabolic process 22325 22325 'Vav2' mRNA 399 440 463 4.27 4.76 5.29 4.6 4.68 5.59 4.773333333 4.956666667 493 491 576 434 520 0.09257831 0.246877762 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0001784///phosphotyrosine residue binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0016477///cell migration+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0050790///regulation of catalytic activity 223254 223254 'Farp1' mRNA 712 742 631 8 8.23 7.54 5.04 5.28 5.16 7.923333333 5.16 515 529 510 695 518 6.64E-05 -0.433084197 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0098978///glutamatergic synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0031267///small GTPase binding GO:0007275///multicellular organism development+++GO:0007416///synapse assembly+++GO:0010923///negative regulation of phosphatase activity+++GO:0048813///dendrite morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1905606///regulation of presynapse assembly 223255 223255 'Stk24' mRNA 1159 1096 750 14.07 13.43 9.36 8.2 7.18 7.9 12.28666667 7.76 790 674 736 1001.666667 733.3333333 4.56E-04 -0.454662339 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009267///cellular response to starvation+++GO:0016310///phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0042542///response to hydrogen peroxide+++GO:0046777///protein autophosphorylation+++GO:0048679///regulation of axon regeneration+++GO:0048680///positive regulation of axon regeneration+++GO:0097194///execution phase of apoptosis 22326 22326 'Vax1' mRNA 1 4 0 0.02 0.07 0 0.05 0.05 0.02 0.03 0.04 3 3 1 1.666666667 2.333333333 0.847786727 0.505803997 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0043010///camera-type eye development+++GO:0060021///roof of mouth development" 223262 223262 'Timm8a2' mRNA 7 8 10 0.15 0.14 0.14 0.02 0.07 0.01 0.143333333 0.033333333 2 4 1 8.333333333 2.333333333 0.127802407 -1.851614352 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0072321///chaperone-mediated protein transport 223267 223267 'Ggact' mRNA 1480 1494 1266 89.08 89.07 80.84 84.08 77.15 86.77 86.33 82.66666667 1579 1391 1539 1413.333333 1503 0.418424855 0.078964719 GO:0005829///cytosol GO:0016829///lyase activity+++GO:0061929///gamma-glutamylaminecyclotransferase activity GO:0042219///cellular modified amino acid catabolic process 22327 22327 'Vbp1' mRNA 1585 1757 1625 57.95 63.34 63.03 59.89 55.11 53.71 61.44 56.23666667 1882 1690 1633 1655.666667 1735 0.595907085 0.054906363 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0016272///prefoldin complex+++GO:0043231///intracellular membrane-bounded organelle GO:0001540///amyloid-beta binding+++GO:0015631///tubulin binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007017///microtubule-based process+++GO:0007021///tubulin complex assembly+++GO:1905907///negative regulation of amyloid fibril formation 223272 223272 'Itgbl1' mRNA 1901.05 2088.12 1887.51 41.76 44.58 43.6 14.69 14.37 13.16 43.31333333 14.07333333 794.03 737.48 686.42 1958.893333 739.31 1.00E-65 -1.417919434 GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009986///cell surface GO:0005178///integrin binding GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0016477///cell migration+++GO:0033627///cell adhesion mediated by integrin 22329 22329 'Vcam1' mRNA 902 1032 1090 14.46 16.28 18.54 27.46 26.79 26.73 16.42666667 26.99333333 1971 1878 1858 1008 1902.333333 1.27E-21 0.900962061 04064///NF-kappa B signaling pathway+++04514///Cell adhesion molecules+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04933///AGE-RAGE signaling pathway in diabetic complications+++05143///African trypanosomiasis+++05144///Malaria+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0002102///podosome+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0042383///sarcolemma+++GO:0045177///apical part of cell+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0071944///cell periphery GO:0005178///integrin binding+++GO:0008131///primary amine oxidase activity+++GO:0050839///cell adhesion molecule binding GO:0001666///response to hypoxia+++GO:0002526///acute inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007507///heart development+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009308///amine metabolic process+++GO:0010043///response to zinc ion+++GO:0010212///response to ionizing radiation+++GO:0016032///viral process+++GO:0022614///membrane to membrane docking+++GO:0032496///response to lipopolysaccharide+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035094///response to nicotine+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0042102///positive regulation of T cell proliferation+++GO:0045471///response to ethanol+++GO:0050901///leukocyte tethering or rolling+++GO:0060326///cell chemotaxis+++GO:0060384///innervation+++GO:0060669///embryonic placenta morphogenesis+++GO:0060710///chorio-allantoic fusion+++GO:0060945///cardiac neuron differentiation+++GO:0061032///visceral serous pericardium development+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0098609///cell-cell adhesion+++GO:0140039///cell-cell adhesion in response to extracellular stimulus+++GO:1904646///cellular response to amyloid-beta 22330 22330 'Vcl' mRNA 3862 4041 4050 39.08 40.2 43.46 18.67 16.17 17.73 40.91333333 17.52333333 2124 1799 1954 3984.333333 1959 3.07E-46 -1.038764264 04510///Focal adhesion+++04520///Adherens junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05146///Amoebiasis GO:0001725///stress fiber+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0005916///fascia adherens+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0090636///outer dense plaque of desmosome+++GO:0090637///inner dense plaque of desmosome+++GO:1990357///terminal web GO:0002162///dystroglycan binding+++GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0045294///alpha-catenin binding+++GO:0051015///actin filament binding GO:0002009///morphogenesis of an epithelium+++GO:0007155///cell adhesion+++GO:0030032///lamellipodium assembly+++GO:0030334///regulation of cell migration+++GO:0034333///adherens junction assembly+++GO:0034394///protein localization to cell surface+++GO:0043297///apical junction assembly+++GO:0048675///axon extension+++GO:0051893///regulation of focal adhesion assembly+++GO:0090136///epithelial cell-cell adhesion+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1904702///regulation of protein localization to cell-cell adherens junction 22333 22333 'Vdac1' mRNA 2859 2969 2216 79.95 81.82 65.79 85.05 69.06 80.71 75.85333333 78.27333333 3494 2771 3210 2681.333333 3158.333333 0.01732011 0.228287832 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04979///Cholesterol metabolism+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0046930///pore complex GO:0000166///nucleotide binding+++GO:0005253///anion channel activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0008308///voltage-gated anion channel activity+++GO:0015288///porin activity+++GO:0015485///cholesterol binding+++GO:0019901///protein kinase binding+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0097001///ceramide binding GO:0001662///behavioral fear response+++GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0006915///apoptotic process+++GO:0007268///chemical synaptic transmission+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007612///learning+++GO:0015698///inorganic anion transport+++GO:0030855///epithelial cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0110099///negative regulation of calcium import into the mitochondrion+++GO:1901526///positive regulation of mitophagy+++GO:1903146///regulation of autophagy of mitochondrion+++GO:2000378///negative regulation of reactive oxygen species metabolic process 223332 223332 'Ranbp3l' mRNA 1001.85 1149.29 1166.08 13.48 14.63 16.03 9.96 9.53 9.19 14.71333333 9.56 842.13 813 801.99 1105.74 819.04 1.59E-05 -0.447482668 GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm GO:0005096///GTPase activator activity+++GO:0046332///SMAD binding GO:0006611///protein export from nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0046907///intracellular transport+++GO:0050790///regulation of catalytic activity+++GO:1901706///mesenchymal cell differentiation involved in bone development 22334 22334 'Vdac2' mRNA 3323 3417 3329 116.43 118.03 123.74 134.77 129.31 136.23 119.4 133.4366667 4420 4139 4323 3356.333333 4294 1.70E-08 0.342786092 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04216///Ferroptosis+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04979///Cholesterol metabolism+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05166///Human T-cell leukemia virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0001669///acrosomal vesicle+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0046930///pore complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0008308///voltage-gated anion channel activity+++GO:0015288///porin activity+++GO:0015485///cholesterol binding+++GO:0031210///phosphatidylcholine binding+++GO:0097001///ceramide binding GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0007339///binding of sperm to zona pellucida+++GO:0015698///inorganic anion transport+++GO:0032272///negative regulation of protein polymerization+++GO:0055085///transmembrane transport+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:0098656///anion transmembrane transport+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 22335 22335 'Vdac3' mRNA 3569 3540 3441 149.68 146.46 153.11 161.32 163.77 168.27 149.75 164.4533333 4415 4373 4455 3516.666667 4414.333333 9.73E-08 0.316230068 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04216///Ferroptosis+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++04979///Cholesterol metabolism+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0046930///pore complex GO:0000166///nucleotide binding+++GO:0008308///voltage-gated anion channel activity+++GO:0015288///porin activity GO:0001662///behavioral fear response+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007612///learning+++GO:0015698///inorganic anion transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902017///regulation of cilium assembly 22337 22337 'Vdr' mRNA 238 228 266 2.94 2.77 3.48 4.02 3.52 3.78 3.063333333 3.773333333 375 321 341 244 345.6666667 0.002665635 0.486070257 "04928///Parathyroid hormone synthesis, secretion and action+++04961///Endocrine and other factor-regulated calcium reabsorption+++04978///Mineral absorption+++05152///Tuberculosis+++05207///Chemical carcinogenesis - receptor activation" GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0016363///nuclear matrix+++GO:0030315///T-tubule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005499///vitamin D binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0038186///lithocholic acid receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0070644///vitamin D response element binding+++GO:1902098///calcitriol binding+++GO:1902121///lithocholic acid binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007275///multicellular organism development+++GO:0007595///lactation+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0010980///positive regulation of vitamin D 24-hydroxylase activity+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0038183///bile acid signaling pathway+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050892///intestinal absorption+++GO:0051924///regulation of calcium ion transport+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060558///regulation of calcidiol 1-monooxygenase activity+++GO:0060745///mammary gland branching involved in pregnancy+++GO:0070561///vitamin D receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:1900155///negative regulation of bone trabecula formation+++GO:2000830///positive regulation of parathyroid hormone secretion" 22339 22339 'Vegfa' mRNA 182 132 131 3.09 2.22 2.41 1.98 1.73 2.17 2.573333333 1.96 118 115 128 148.3333333 120.3333333 0.22173864 -0.31130905 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04066///HIF-1 signaling pathway+++04151///PI3K-Akt signaling pathway+++04370///VEGF signaling pathway+++04510///Focal adhesion+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05219///Bladder cancer+++05323///Rheumatoid arthritis+++05418///Fluid shear stress and atherosclerosis GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031982///vesicle GO:0001968///fibronectin binding+++GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0019838///growth factor binding+++GO:0038191///neuropilin binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0043183///vascular endothelial growth factor receptor 1 binding+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0048018///receptor ligand activity+++GO:0050840///extracellular matrix binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001568///blood vessel development+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001666///response to hypoxia+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001944///vasculature development+++GO:0001946///lymphangiogenesis+++GO:0001974///blood vessel remodeling+++GO:0002040///sprouting angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002092///positive regulation of receptor internalization+++GO:0002575///basophil chemotaxis+++GO:0003007///heart morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003169///coronary vein morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007498///mesoderm development+++GO:0007595///lactation+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009967///positive regulation of signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010749///regulation of nitric oxide mediated signal transduction+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016477///cell migration+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030224///monocyte differentiation+++GO:0030225///macrophage differentiation+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030855///epithelial cell differentiation+++GO:0031077///post-embryonic camera-type eye development+++GO:0031334///positive regulation of protein complex assembly+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035148///tube formation+++GO:0035767///endothelial cell chemotaxis+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036303///lymph vessel morphogenesis+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:0038091///positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway+++GO:0038190///VEGF-activated neuropilin signaling pathway+++GO:0040008///regulation of growth+++GO:0042088///T-helper 1 type immune response+++GO:0042311///vasodilation+++GO:0042327///positive regulation of phosphorylation+++GO:0042462///eye photoreceptor cell development+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043117///positive regulation of vascular permeability+++GO:0043129///surfactant homeostasis+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0043542///endothelial cell migration+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045601///regulation of endothelial cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045779///negative regulation of bone resorption+++GO:0045785///positive regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048255///mRNA stabilization+++GO:0048286///lung alveolus development+++GO:0048469///cell maturation+++GO:0048514///blood vessel morphogenesis+++GO:0048593///camera-type eye morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048666///neuron development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0048844///artery morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0050927///positive regulation of positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051272///positive regulation of cellular component movement+++GO:0051781///positive regulation of cell division+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055013///cardiac muscle cell development+++GO:0060319///primitive erythrocyte differentiation+++GO:0060326///cell chemotaxis+++GO:0060346///bone trabecula formation+++GO:0060426///lung vasculature development+++GO:0060749///mammary gland alveolus development+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0060948///cardiac vascular smooth muscle cell development+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0061042///vascular wound healing+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0061430///bone trabecula morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071456///cellular response to hypoxia+++GO:0071542///dopaminergic neuron differentiation+++GO:0071679///commissural neuron axon guidance+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090259///regulation of retinal ganglion cell axon guidance+++GO:0097475///motor neuron migration+++GO:0097533///cellular stress response to acid chemical+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901165///positive regulation of trophoblast cell migration+++GO:1901215///negative regulation of neuron death+++GO:1901492///positive regulation of lymphangiogenesis+++GO:1901532///regulation of hematopoietic progenitor cell differentiation+++GO:1901727///positive regulation of histone deacetylase activity+++GO:1902336///positive regulation of retinal ganglion cell axon guidance+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1903141///negative regulation of establishment of endothelial barrier+++GO:1903392///negative regulation of adherens junction organization+++GO:1903572///positive regulation of protein kinase D signaling+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1905278///positive regulation of epithelial tube formation+++GO:1905604///negative regulation of maintenance of permeability of blood-brain barrier+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 22340 22340 'Vegfb' mRNA 330 353 254 16.14 17.07 13.16 11.47 11.94 11.1 15.45666667 11.50333333 268 273 250 312.3333333 263.6666667 0.152100827 -0.250373172 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular+++GO:0016020///membrane GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding+++GO:0042056///chemoattractant activity+++GO:0042802///identical protein binding+++GO:0043183///vascular endothelial growth factor receptor 1 binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0006493///protein O-linked glycosylation+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0035470///positive regulation of vascular wound healing+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060048///cardiac muscle contraction+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0060976///coronary vasculature development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 22341 22341 'Vegfc' mRNA 34.82 34.64 40.63 1.06 1.04 1.31 1.37 1.75 2.18 1.136666667 1.766666667 51.74 64.51 79.57 36.69666667 65.27333333 0.029254866 0.832147613 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04668///TNF signaling pathway+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane GO:0005172///vascular endothelial growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity+++GO:0043185///vascular endothelial growth factor receptor 3 binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002040///sprouting angiogenesis+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0042493///response to drug+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0045860///positive regulation of protein kinase activity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050714///positive regulation of protein secretion+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050918///positive chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:1901492///positive regulation of lymphangiogenesis+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:1990830///cellular response to leukemia inhibitory factor 22342 22342 'Lin7b' mRNA 43 53 47 4.25 5.21 4.94 1.99 1.51 0.63 4.8 1.376666667 23 17 7 47.66666667 15.66666667 0.001135819 -1.620499429 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030658///transport vesicle membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0098793///presynapse+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0097016///L27 domain binding GO:0006887///exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0015031///protein transport+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1903361///protein localization to basolateral plasma membrane 22343 22343 'Lin7c' mRNA 2234 2313 2312 29.1 29.63 31.94 26.59 23.76 26.03 30.22333333 25.46 2350 2051 2228 2286.333333 2209.666667 0.495556771 -0.06315773 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030658///transport vesicle membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0098793///presynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0097016///L27 domain binding GO:0002011///morphogenesis of an epithelial sheet+++GO:0006887///exocytosis+++GO:0007269///neurotransmitter secretion+++GO:0015031///protein transport+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1903361///protein localization to basolateral plasma membrane 223433 223433 'Otulinl' mRNA 133 119 63 2.44 2.15 1.23 10.11 19.44 14.75 1.94 14.76666667 632 1188 893 105 904.3333333 1.17E-14 3.114776882 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane GO:0003674///molecular_function+++GO:0019783///ubiquitin-like protein-specific protease activity+++GO:0043130///ubiquitin binding GO:0006508///proteolysis+++GO:0008150///biological_process+++GO:0016579///protein deubiquitination 223435 223435 'Trio' mRNA 948.19 920.45 709.87 3.16 3 2.56 2.15 2.04 2.3 2.906666667 2.163333333 864.98 718 819.59 859.5033333 800.8566667 0.408876167 -0.109960299 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0019898///extrinsic component of membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding GO:0006468///protein phosphorylation+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0016310///phosphorylation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0050790///regulation of catalytic activity 22344 22344 'Vezf1' mRNA 2502 2388 2192 27.49 26.05 26.01 18.23 15.61 17.16 26.51666667 17 1892 1558 1695 2360.666667 1715 1.08E-09 -0.47277636 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific" GO:0001525///angiogenesis+++GO:0001885///endothelial cell development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 223453 223453 'Dap' mRNA 1235 1217 1113 49.37 47.99 47.21 56.07 61.14 57.96 48.19 58.39 1611 1714 1611 1188.333333 1645.333333 9.27E-09 0.459667364 GO:0005575///cellular_component GO:0070513///death domain binding "GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0010507///negative regulation of autophagy+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034198///cellular response to amino acid starvation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0097190///apoptotic signaling pathway" 223455 223455 'Marchf6' mRNA 1988 1932 1684 16.85 16.11 15.15 17.86 16.78 16.89 16.03666667 17.17666667 2421 2224 2221 1868 2288.666667 9.80E-05 0.283081092 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990381///ubiquitin-specific protease binding GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 22346 22346 'Vhl' mRNA 1144 1337 1266 22.93 26.37 26.91 23.06 24.58 23.84 25.40333333 23.82666667 1324 1378 1325 1249 1342.333333 0.400891025 0.091873262 04066///HIF-1 signaling pathway+++04120///Ubiquitin mediated proteolysis+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030891///VCB complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0003309///type B pancreatic cell differentiation+++GO:0003310///pancreatic A cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006582///melanin metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010498///proteasomal protein catabolic process+++GO:0010629///negative regulation of gene expression+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0030182///neuron differentiation+++GO:0030198///extracellular matrix organization+++GO:0032880///regulation of protein localization+++GO:0042069///regulation of catecholamine metabolic process+++GO:0043534///blood vessel endothelial cell migration+++GO:0045471///response to ethanol+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0048069///eye pigmentation+++GO:0048593///camera-type eye morphogenesis+++GO:0048877///homeostasis of number of retina cells+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0061072///iris morphogenesis+++GO:0061073///ciliary body morphogenesis+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0070243///regulation of thymocyte apoptotic process+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0099175///regulation of postsynapse organization+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1902072///negative regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:1903827///regulation of cellular protein localization+++GO:2001233///regulation of apoptotic signaling pathway" 223473 223473 'Nipal2' mRNA 665.35 635.54 515.34 7.1 6.79 5.91 4.35 3.85 3.88 6.6 4.026666667 448 399.05 392.84 605.41 413.2966667 6.29E-06 -0.559370131 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0015095///magnesium ion transmembrane transporter activity GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 22348 22348 'Slc32a1' mRNA 1 0 1 0.01 0 0.01 0.02 0 0.02 0.006666667 0.013333333 1 0 1 0.666666667 0.666666667 0.998591786 -0.04083861 04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0044292///dendrite terminus+++GO:0044306///neuron projection terminus+++GO:0044316///cone cell pedicle+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0051286///cell tip+++GO:0060077///inhibitory synapse+++GO:0098982///GABA-ergic synapse GO:0015187///glycine transmembrane transporter activity+++GO:0015495///gamma-aminobutyric acid:proton symporter activity GO:0006836///neurotransmitter transport+++GO:0007568///aging+++GO:0015812///gamma-aminobutyric acid transport+++GO:0015816///glycine transport+++GO:0021766///hippocampus development+++GO:0098700///neurotransmitter loading into synaptic vesicle 22349 22349 'Vil1' mRNA 24 7 18 0.42 0.12 0.34 0.49 0.41 0.41 0.293333333 0.436666667 32 26 26 16.33333333 28 0.236994279 0.757748273 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0032432///actin filament bundle+++GO:0032433///filopodium tip+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0035727///lysophosphatidic acid binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding" GO:0001951///intestinal D-glucose absorption+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008154///actin polymerization or depolymerization+++GO:0008360///regulation of cell shape+++GO:0009617///response to bacterium+++GO:0010634///positive regulation of epithelial cell migration+++GO:0030033///microvillus assembly+++GO:0030041///actin filament polymerization+++GO:0030042///actin filament depolymerization+++GO:0030335///positive regulation of cell migration+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030855///epithelial cell differentiation+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0032532///regulation of microvillus length+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0040018///positive regulation of multicellular organism growth+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045010///actin nucleation+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051125///regulation of actin nucleation+++GO:0051693///actin filament capping+++GO:0060327///cytoplasmic actin-based contraction involved in cell motility+++GO:0061041///regulation of wound healing+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1902896///terminal web assembly+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:2000394///positive regulation of lamellipodium morphogenesis 223499 223499 'Dcaf13' mRNA 620 595 678 23.81 22.47 27.53 36.24 33.76 35.75 24.60333333 35.25 1088 989 1037 631 1038 2.54E-11 0.70243997 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0032040///small-subunit processome+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0030331///estrogen receptor binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0016567///protein ubiquitination+++GO:0042254///ribosome biogenesis" 22350 22350 'Ezr' mRNA 3751 3985 3934 67.01 70.05 74.55 66.53 61.2 63.59 70.53666667 63.77333333 4285 3850 3966 3890 4033.666667 0.663012966 0.038506396 04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04971///Gastric acid secretion+++05130///Pathogenic Escherichia coli infection+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer GO:0001650///fibrillar center+++GO:0001726///ruffle+++GO:0001772///immunological synapse+++GO:0001931///uropod+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0030175///filopodium+++GO:0030315///T-tubule+++GO:0031528///microvillus membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0044297///cell body+++GO:0044393///microspike+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip+++GO:0071944///cell periphery+++GO:0097449///astrocyte projection+++GO:0097454///Schwann cell microvillus+++GO:0098592///cytoplasmic side of apical plasma membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042802///identical protein binding+++GO:0044548///S100 protein binding+++GO:0044877///protein-containing complex binding+++GO:0050839///cell adhesion molecule binding+++GO:0051015///actin filament binding+++GO:0051018///protein kinase A binding+++GO:0051117///ATPase binding+++GO:0097718///disordered domain specific binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001951///intestinal D-glucose absorption+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007159///leukocyte cell-cell adhesion+++GO:0008360///regulation of cell shape+++GO:0010628///positive regulation of gene expression+++GO:0010737///protein kinase A signaling+++GO:0022614///membrane to membrane docking+++GO:0030033///microvillus assembly+++GO:0030855///epithelial cell differentiation+++GO:0030953///astral microtubule organization+++GO:0031503///protein-containing complex localization+++GO:0031532///actin cytoskeleton reorganization+++GO:0031623///receptor internalization+++GO:0032532///regulation of microvillus length+++GO:0032703///negative regulation of interleukin-2 production+++GO:0034629///cellular protein-containing complex localization+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0040018///positive regulation of multicellular organism growth+++GO:0043622///cortical microtubule organization+++GO:0046847///filopodium assembly+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050714///positive regulation of protein secretion+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051017///actin filament bundle assembly+++GO:0051660///establishment of centrosome localization+++GO:0061028///establishment of endothelial barrier+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0072659///protein localization to plasma membrane+++GO:0072697///protein localization to cell cortex+++GO:1902115///regulation of organelle assembly+++GO:1902896///terminal web assembly+++GO:1902966///positive regulation of protein localization to early endosome+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1903753///negative regulation of p38MAPK cascade+++GO:2000643///positive regulation of early endosome to late endosome transport 22351 22351 'Vill' mRNA 164 239 203 3.37 4.79 4.51 8.01 7.56 7.47 4.223333333 7.68 382 347 351 202 360 1.14E-06 0.821411784 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0032433///filopodium tip+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding" GO:0007010///cytoskeleton organization+++GO:0008154///actin polymerization or depolymerization+++GO:0045010///actin nucleation+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping 223513 223513 'Abra' mRNA 1 0 1 0.03 0 0.03 0.09 0 0.03 0.02 0.04 3 0 1 0.666666667 1.333333333 0.785089919 0.951473788 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril+++GO:0030017///sarcomere GO:0003779///actin binding "GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity" 22352 22352 'Vim' mRNA 1664 1765 1592 52.17 54.54 52.95 287.68 247.92 281.68 53.22 272.4266667 10546 8871 9993 1673.666667 9803.333333 0 2.538183134 05169///Epstein-Barr virus infection+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030424///axon+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045098///type III intermediate filament+++GO:0045111///intermediate filament cytoskeleton+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0051721///protein phosphatase 2A binding+++GO:0097110///scaffold protein binding+++GO:1990254///keratin filament binding GO:0007010///cytoskeleton organization+++GO:0010628///positive regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0014002///astrocyte development+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0045103///intermediate filament-based process+++GO:0045109///intermediate filament organization+++GO:0045727///positive regulation of translation+++GO:0050770///regulation of axonogenesis+++GO:0060020///Bergmann glial cell differentiation+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060395///SMAD protein signal transduction+++GO:0070307///lens fiber cell development+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071225///cellular response to muramyl dipeptide+++GO:0071346///cellular response to interferon-gamma+++GO:1900147///regulation of Schwann cell migration 223527 223527 'Eny2' mRNA 944.56 851.54 850.76 20.73 18.24 19.87 24.06 25.01 23.9 19.61333333 24.32333333 1253.58 1274.36 1209 882.2866667 1245.646667 6.19E-08 0.486868067 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0044615///nuclear pore nuclear basket+++GO:0070390///transcription export complex 2+++GO:0071819///DUBm complex GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006406///mRNA export from nucleus+++GO:0015031///protein transport+++GO:0016578///histone deubiquitination+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051028///mRNA transport+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus" 22353 22353 'Vip' mRNA 4 2 0 0.15 0.08 0 0.03 0 0 0.076666667 0.01 1 0 0 2 0.333333333 0.425801777 -2.461127191 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0051428///peptide hormone receptor binding GO:0001878///response to yeast+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007611///learning or memory+++GO:0009966///regulation of signal transduction+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0032812///positive regulation of epinephrine secretion+++GO:0032880///regulation of protein localization+++GO:0043066///negative regulation of apoptotic process+++GO:0043267///negative regulation of potassium ion transport+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0048242///epinephrine secretion+++GO:0048255///mRNA stabilization+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051930///regulation of sensory perception of pain+++GO:0060406///positive regulation of penile erection+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070459///prolactin secretion 22354 22354 'Vipr1' mRNA 74 118 70 0.81 1.27 0.81 0.31 0.19 0.22 0.963333333 0.24 33 20 22 87.33333333 25 1.09E-06 -1.812236271 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004999///vasoactive intestinal polypeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding "GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway" 22355 22355 'Vipr2' mRNA 4 10 6 0.07 0.16 0.1 0.07 0.04 0.01 0.11 0.04 8 3 1 6.666666667 4 0.59486514 -0.754525327 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004999///vasoactive intestinal polypeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0048662///negative regulation of smooth muscle cell proliferation 22359 22359 'Vldlr' mRNA 288 347.51 264 1.87 2.23 1.85 0.69 0.56 0.59 1.983333333 0.613333333 120 95 102 299.8366667 105.6666667 2.72E-16 -1.513279465 05017///Spinocerebellar ataxia+++05417///Lipid and atherosclerosis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0043235///receptor complex+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030229///very-low-density lipoprotein particle receptor activity+++GO:0034185///apolipoprotein binding+++GO:0034189///very-low-density lipoprotein particle binding+++GO:0038024///cargo receptor activity+++GO:0038025///reelin receptor activity+++GO:0048306///calcium-dependent protein binding GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0021517///ventral spinal cord development+++GO:0034436///glycoprotein transport+++GO:0034447///very-low-density lipoprotein particle clearance+++GO:0038026///reelin-mediated signaling pathway+++GO:0045860///positive regulation of protein kinase activity+++GO:0048813///dendrite morphogenesis+++GO:0071456///cellular response to hypoxia+++GO:1900006///positive regulation of dendrite development 223593 223593 'Washc5' mRNA 777 906 830 10.34 11.86 11.72 16.29 16.39 15.95 11.30666667 16.21 1408 1384 1336 837.6666667 1376 3.98E-15 0.704261397 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0071203///WASH complex GO:0042802///identical protein binding GO:0001556///oocyte maturation+++GO:0006887///exocytosis+++GO:0006909///phagocytosis+++GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0030041///actin filament polymerization+++GO:0031503///protein-containing complex localization+++GO:0034629///cellular protein-containing complex localization+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0042632///cholesterol homeostasis+++GO:0043933///protein-containing complex subunit organization+++GO:0051125///regulation of actin nucleation+++GO:0090306///spindle assembly involved in meiosis+++GO:0097494///regulation of vesicle size 22360 22360 'Nrsn1' mRNA 280 355 296 7.39 9.23 8.31 0.32 0.31 0.52 8.31 0.383333333 14 13 22 310.3333333 16.33333333 2.22E-52 -4.258040207 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0007399///nervous system development 223601 223601 'Cyrib' mRNA 387.04 440 307 6.97 7.84 5.09 16.89 27.92 24.52 6.633333333 23.11 909.39 1393.36 1234 378.0133333 1178.916667 1.34E-27 1.639373033 GO:0005739///mitochondrion+++GO:0005929///cilium+++GO:0016020///membrane "GO:0005515///protein binding+++GO:0023030///MHC class Ib protein binding, via antigen binding groove+++GO:0031267///small GTPase binding" GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0030334///regulation of cell migration+++GO:0030833///regulation of actin filament polymerization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032729///positive regulation of interferon-gamma production+++GO:0050870///positive regulation of T cell activation+++GO:0050920///regulation of chemotaxis+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0090140///regulation of mitochondrial fission+++GO:2000114///regulation of establishment of cell polarity+++GO:2000568///positive regulation of memory T cell activation 223604 223604 'Kcnk9' mRNA 3 0 0 0.02 0 0 0.01 0 0 0.006666667 0.003333333 1 0 0 1 0.333333333 0.750798057 -1.467430888 04925///Aldosterone synthesis and secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0071805///potassium ion transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 22361 22361 'Vnn1' mRNA 171 186 179 3.96 4.31 4.39 2.6 2.59 1.87 4.22 2.353333333 124 126 90 178.6666667 113.3333333 0.002748407 -0.669314037 00770///Pantothenate and CoA biosynthesis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane "GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0017159///pantetheine hydrolase activity+++GO:0034235///GPI anchor binding" GO:0002526///acute inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0006807///nitrogen compound metabolic process+++GO:0006954///inflammatory response+++GO:0015939///pantothenate metabolic process+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0045087///innate immune response+++GO:0098609///cell-cell adhesion+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 22362 22362 'Vpreb1' mRNA 2 3 1 0.18 0.27 0.1 0.71 0.78 0.9 0.183333333 0.796666667 9 9.62 11 2 9.873333333 0.05065939 2.272597167 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0000902///cell morphogenesis+++GO:0002377///immunoglobulin production+++GO:0006955///immune response+++GO:0008361///regulation of cell size+++GO:0030097///hemopoiesis+++GO:0042100///B cell proliferation+++GO:0048872///homeostasis of number of cells 223626 223626 'Them6' mRNA 29 22 11 1.15 0.86 0.46 0.69 0.82 0.82 0.823333333 0.776666667 20 23 23 20.66666667 22 0.896451793 0.092679817 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 22363 22363 'Vpreb2' mRNA 1 1 0 0.06 0.06 0 0 0.11 0.05 0.04 0.053333333 0 2.38 1 0.666666667 1.126666667 0.863090843 0.617167445 GO:0005615///extracellular space GO:0000902///cell morphogenesis+++GO:0002377///immunoglobulin production+++GO:0006955///immune response+++GO:0008361///regulation of cell size+++GO:0042100///B cell proliferation+++GO:0048872///homeostasis of number of cells 22364 22364 'Vpreb3' mRNA 24 24 28 2.58 2.2 2.87 3.45 4.61 2.91 2.55 3.656666667 37 53 31 25.33333333 40.33333333 0.181694039 0.658339147 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum GO:0003674///molecular_function GO:0002377///immunoglobulin production+++GO:0002638///negative regulation of immunoglobulin production+++GO:0006955///immune response 223642 223642 'Zc3h3' mRNA 767 744 537 13.72 12.4 9.65 7.42 6.52 6.55 11.92333333 6.83 515 428 439 682.6666667 460.6666667 1.72E-05 -0.574150956 GO:0005634///nucleus+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding GO:0031124///mRNA 3'-end processing+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0051028///mRNA transport+++GO:1900363///regulation of mRNA polyadenylation 223645 223645 'Mroh6' mRNA 12 14 9 0.14 0.15 0.11 0.25 0.33 0.17 0.133333333 0.25 24 33 16 11.66666667 24.33333333 0.104748282 1.057157393 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 223646 223646 'Naprt' mRNA 682 701 605 22.95 23.41 21.66 32.05 35.1 34.71 22.67333333 33.95333333 1079 1147 1139 662.6666667 1121.666667 7.61E-16 0.750442259 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0004516///nicotinate phosphoribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006979///response to oxidative stress+++GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0034355///NAD salvage 223648 223648 'Ccdc166' mRNA 305 232 269 7.08 5.29 6.62 3.72 4.02 2.97 6.33 3.57 184 195 143 268.6666667 174 0.001164674 -0.64003148 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 223649 223649 'Nrbp2' mRNA 4407 4394 3824 73.89 72.49 68.01 42.44 40.25 42.27 71.46333333 41.65333333 2913 2698 2809 4208.333333 2806.666667 2.33E-23 -0.59421883 GO:0005737///cytoplasm+++GO:0012505///endomembrane system GO:0003674///molecular_function+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007399///nervous system development+++GO:0016242///negative regulation of macroautophagy+++GO:0030182///neuron differentiation+++GO:0035556///intracellular signal transduction+++GO:0043524///negative regulation of neuron apoptotic process 22365 22365 'Vps45' mRNA 695 674 706 14.16 13.63 15.07 10.78 11.78 10.04 14.28666667 10.86666667 593 640 540 691.6666667 591 0.052993034 -0.239700899 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 223650 223650 'Eppk1' mRNA 1080.86 1129.91 854.84 2.59 2.66 2.18 2.62 2.66 2.82 2.476666667 2.7 1256.77 1247.55 1312 1021.87 1272.106667 0.001533547 0.310169588 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0042995///cell projection+++GO:0045095///keratin filament+++GO:0045178///basal part of cell+++GO:0071944///cell periphery+++GO:0097356///perinucleolar compartment GO:0005198///structural molecule activity+++GO:0019215///intermediate filament binding+++GO:1990254///keratin filament binding GO:0007010///cytoskeleton organization+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0030336///negative regulation of cell migration+++GO:0030856///regulation of epithelial cell differentiation+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045109///intermediate filament organization+++GO:0045110///intermediate filament bundle assembly+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051548///negative regulation of keratinocyte migration+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0061045///negative regulation of wound healing+++GO:1905041///regulation of epithelium regeneration 223658 223658 'Mroh1' mRNA 1646 1699 1605 16.71 16.82 17.13 17.58 16.1 15.32 16.88666667 16.33333333 1982.72 1787.4 1685.94 1650 1818.686667 0.144691975 0.127346446 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 223664 223664 'Lrrc14' mRNA 700 803 718 16.94 18.91 18.42 15.98 17.09 18.28 18.09 17.11666667 767 796 831 740.3333333 798 0.431415539 0.097731559 GO:0005737///cytoplasm GO:0019900///kinase binding GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034122///negative regulation of toll-like receptor signaling pathway 223665 223665 'C030006K11Rik' mRNA 353 351 280 11.55 11.33 9.74 8.93 9.49 8.65 10.87333333 9.023333333 313 326 295 328 311.3333333 0.668405626 -0.082684629 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 223666 223666 'Arhgap39' mRNA 1288.64 1319.92 912.06 9.44 9.63 5.97 3.89 3.62 3.95 8.346666667 3.82 695.88 626.59 680.5 1173.54 667.6566667 8.38E-13 -0.819488428 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0099173///postsynapse organization 223669 223669 'Zfp7' mRNA 252 249 297 4.81 4.49 5.93 4.22 4.05 4.12 5.076666667 4.13 253 240 240 266 244.3333333 0.500901273 -0.139167222 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22367 22367 'Vrk1' mRNA 335 396 377 4.58 5.38 5.54 6.55 7.44 7.49 5.166666667 7.16 547 606 597 369.3333333 583.3333333 5.89E-07 0.647937647 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031493///nucleosomal histone binding+++GO:0035175///histone kinase activity (H3-S10 specific)+++GO:0072354///histone kinase activity (H3-T3 specific) GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043987///histone H3-S10 phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0051301///cell division+++GO:0072355///histone H3-T3 phosphorylation+++GO:0090166///Golgi disassembly 223672 223672 'Apol9a' mRNA 13.53 11.09 8.28 0.54 0.44 0.35 2.81 1.77 2.72 0.443333333 2.433333333 81.31 49.3 77.12 10.96666667 69.24333333 3.21E-09 2.682741048 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 22368 22368 'Trpv2' mRNA 48 52 66 0.97 1.06 1.46 13.86 14.39 13.81 1.163333333 14.02 771 786 758 55.33333333 771.6666667 3.58E-116 3.78801937 04621///NOD-like receptor signaling pathway+++04750///Inflammatory mediator regulation of TRP channels GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0032584///growth cone membrane+++GO:0042470///melanosome+++GO:0044295///axonal growth cone+++GO:0044297///cell body GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0009266///response to temperature stimulus+++GO:0009408///response to heat+++GO:0045773///positive regulation of axon extension+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0090280///positive regulation of calcium ion import+++GO:0098703///calcium ion import across plasma membrane+++GO:0120162///positive regulation of cold-induced thermogenesis 223690 223690 'Ankrd54' mRNA 1129 1240 1206 34.44 37.15 38.89 25.89 24.98 26.53 36.82666667 25.8 979 923 973 1191.666667 958.3333333 3.97E-04 -0.327350978 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030496///midbody GO:0005515///protein binding+++GO:0019887///protein kinase regulator activity+++GO:0044877///protein-containing complex binding GO:0006913///nucleocytoplasmic transport+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045859///regulation of protein kinase activity+++GO:1902531///regulation of intracellular signal transduction 223691 223691 'Eif3l' mRNA 1967 1991 2083 59.53 59.37 66.88 67.85 65.22 67.27 61.92666667 66.78 2577 2418 2473 2013.666667 2489.333333 1.48E-04 0.291711459 GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex GO:0003743///translation initiation factor activity+++GO:0005515///protein binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0075525///viral translational termination-reinitiation 223693 223693 'Tmem184b' mRNA 2302.03 2311.77 2292 37.03 36.4 38.96 46.33 41.56 43.44 37.46333333 43.77666667 3236 2878 2993 2301.933333 3035.666667 1.64E-08 0.385957516 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity GO:0006810///transport 223696 223696 'Tomm22' mRNA 1150 1081 1114 71.39 66.35 73.38 83.21 82.42 84.14 70.37333333 83.25666667 1537 1484 1502 1115 1507.666667 3.21E-07 0.422506648 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0043065///positive regulation of apoptotic process+++GO:0045040///protein import into mitochondrial outer membrane+++GO:0051204///protein insertion into mitochondrial membrane+++GO:0071806///protein transmembrane transport 223697 223697 'Sun2' mRNA 255 249 216 4.06 4.08 3.26 3.39 2.83 4.07 3.8 3.43 257 200 296 240 251 0.83530643 0.054220794 "GO:0000781///chromosome, telomeric region+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex" GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0042802///identical protein binding+++GO:0043495///protein membrane anchor GO:0006998///nuclear envelope organization+++GO:0021817///nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration+++GO:0030335///positive regulation of cell migration+++GO:0031022///nuclear migration along microfilament+++GO:0051321///meiotic cell cycle+++GO:0051642///centrosome localization+++GO:0090292///nuclear matrix anchoring at nuclear membrane 22370 22370 'Vtn' mRNA 743 740 714 24.64 24.19 25.12 21.61 24.21 25.88 24.65 23.9 749 819 868 732.3333333 812 0.247973424 0.13842066 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04610///Complement and coagulation cascades+++05165///Human papillomavirus infection+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005796///Golgi lumen+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048237///rough endoplasmic reticulum lumen+++GO:0062023///collagen-containing extracellular matrix GO:0005044///scavenger receptor activity+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0030247///polysaccharide binding+++GO:0042802///identical protein binding+++GO:0050840///extracellular matrix binding GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010951///negative regulation of endopeptidase activity+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016477///cell migration+++GO:0030198///extracellular matrix organization+++GO:0032092///positive regulation of protein binding+++GO:0033627///cell adhesion mediated by integrin+++GO:0035987///endodermal cell differentiation+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048709///oligodendrocyte differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051258///protein polymerization+++GO:0061302///smooth muscle cell-matrix adhesion+++GO:0097421///liver regeneration 223701 223701 'Mrtfa' mRNA 530 445 425 6.59 5.42 5.59 9.3 8.85 9.29 5.866666667 9.146666667 855 801 830 466.6666667 828.6666667 1.01E-13 0.81791306 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft+++GO:0120003///hinge region between urothelial plaques of apical plasma membrane GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0019911///structural constituent of myelin sheath+++GO:0043522///leucine zipper domain binding "GO:0001764///neuron migration+++GO:0002175///protein localization to paranode region of axon+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010735///positive regulation of transcription via serum response element binding+++GO:0030036///actin cytoskeleton organization+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0042552///myelination+++GO:0043086///negative regulation of catalytic activity+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044319///wound healing, spreading of cells+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051145///smooth muscle cell differentiation+++GO:0098737///protein insertion into plasma membrane+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:2001234///negative regulation of apoptotic signaling pathway" 22371 22371 'Vwf' mRNA 782 784 733 4.65 4.58 4.62 3.73 3.44 3.68 4.616666667 3.616666667 723 652 692 766.3333333 689 0.126810551 -0.16515642 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04610///Complement and coagulation cascades+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++05165///Human papillomavirus infection+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0009897///external side of plasma membrane+++GO:0031012///extracellular matrix+++GO:0033093///Weibel-Palade body+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0019865///immunoglobulin binding+++GO:0042802///identical protein binding+++GO:0047485///protein N-terminus binding+++GO:0051087///chaperone binding GO:0001889///liver development+++GO:0001890///placenta development+++GO:0007155///cell adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030168///platelet activation+++GO:0031589///cell-substrate adhesion+++GO:1902533///positive regulation of intracellular signal transduction 223722 223722 'Mcat' mRNA 159 125 84 4.87 3.73 2.7 3.4 2.45 3.1 3.766666667 2.983333333 129 91 114 122.6666667 111.3333333 0.678581764 -0.145194081 00061///Fatty acid biosynthesis+++01212///Fatty acid metabolism GO:0005739///mitochondrion GO:0004312///fatty acid synthase activity+++GO:0004314///[acyl-carrier-protein] S-malonyltransferase activity+++GO:0016419///S-malonyltransferase activity+++GO:0016740///transferase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process 223723 223723 'Ttll12' mRNA 979 883 866 14.06 12.48 13.19 13.13 11.92 13.09 13.24333333 12.71333333 1052 933 1016 909.3333333 1000.333333 0.240386461 0.125592262 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:1990889///H4K20me3 modified histone binding GO:0002376///immune system process+++GO:0006464///cellular protein modification process+++GO:0007346///regulation of mitotic cell cycle+++GO:0045087///innate immune response+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway 223726 223726 'Mpped1' mRNA 2 0 0 0.03 0 0 0.01 0 0.05 0.01 0.02 1 0 3 0.666666667 1.333333333 0.78758696 1.006623743 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0008150///biological_process 223732 223732 'Rtl6' mRNA 846 965 1012 10.27 11.52 13.03 4.06 3.32 4.23 11.60666667 3.87 385 308 389 941 360.6666667 1.89E-28 -1.399890186 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 223739 223739 '5031439G07Rik' mRNA 2488 2571 2411 19.94 20.21 20.26 21.36 20.58 20.68 20.13666667 20.87333333 3105 2929 2922 2490 2985.333333 9.11E-05 0.249965107 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 22375 22375 'Wars' mRNA 1747 1817 1885 34.88 35.67 39.42 33.91 35.07 32.29 36.65666667 33.75666667 1939 1952 1760 1816.333333 1883.666667 0.740504164 0.038649878 00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0019210///kinase inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity GO:0001525///angiogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0010628///positive regulation of gene expression+++GO:0010835///regulation of protein ADP-ribosylation+++GO:0031334///positive regulation of protein complex assembly+++GO:0045765///regulation of angiogenesis 223752 223752 'Gramd4' mRNA 384 430 363 4.48 4.66 4.32 2.65 2.63 2.79 4.486666667 2.69 278 289 300 392.3333333 289 0.001632365 -0.450178224 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0034164///negative regulation of toll-like receptor 9 signaling pathway+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 223753 223753 'Cerk' mRNA 448 568 382 5.96 7.56 5.47 10.42 10.94 11.89 6.33 11.08333333 890 906 979 466 925 1.03E-15 0.983862339 00600///Sphingolipid metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001727///lipid kinase activity+++GO:0001729///ceramide kinase activity+++GO:0003951///NAD+ kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0102773///dihydroceramide kinase activity GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0016310///phosphorylation+++GO:0046834///lipid phosphorylation 223754 223754 'Tbc1d22a' mRNA 1724.66 1652.44 1795.87 20.3 19.81 23 27.22 27.26 25.92 21.03666667 26.8 2627.38 2591.41 2414.43 1724.323333 2544.406667 9.58E-12 0.547285242 GO:0005096///GTPase activator activity+++GO:0042803///protein homodimerization activity+++GO:0071889///14-3-3 protein binding GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 22376 22376 'Was' mRNA 44 64 34 1.19 1.71 0.98 13.34 13.28 13.13 1.293333333 13.25 567 551 540 47.33333333 552.6666667 3.88E-79 3.53887574 04062///Chemokine signaling pathway+++04520///Adherens junction+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++05135///Yersinia infection+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0012506///vesicle membrane+++GO:0035861///site of double-strand break+++GO:0045335///phagocytic vesicle GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding GO:0002625///regulation of T cell antigen processing and presentation+++GO:0006955///immune response+++GO:0007015///actin filament organization+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0008154///actin polymerization or depolymerization+++GO:0010591///regulation of lamellipodium assembly+++GO:0016197///endosomal transport+++GO:0030041///actin filament polymerization+++GO:0030048///actin filament-based movement+++GO:0032488///Cdc42 protein signal transduction+++GO:0042110///T cell activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051492///regulation of stress fiber assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0071346///cellular response to interferon-gamma+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2000146///negative regulation of cell motility+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 22377 22377 'Wbp1' mRNA 3168 3188 2413 145.47 144.17 117.45 55.69 57.66 59.19 135.6966667 57.51333333 1379 1391 1420 2923 1396.666667 4.35E-37 -1.071244262 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0050699///WW domain binding GO:0008150///biological_process 223770 223770 'Brd1' mRNA 596 560 628 6.43 5.97 7.25 6.53 5.57 6.54 6.55 6.213333333 695 587 676 594.6666667 652.6666667 0.403133079 0.118571799 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0036409///histone H3-K14 acetyltransferase complex+++GO:0043204///perikaryon+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0006325///chromatin organization+++GO:0035902///response to immobilization stress+++GO:0043249///erythrocyte maturation+++GO:0043966///histone H3 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0051602///response to electrical stimulus 223773 223773 'Zbed4' mRNA 223.48 242.85 260.79 1.65 1.77 1.97 1.88 1.72 2.02 1.796666667 1.873333333 285.23 262.11 316.23 242.3733333 287.8566667 0.204179944 0.236606277 GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity GO:0045944///positive regulation of transcription by RNA polymerase II 223774 223774 'Alg12' mRNA 519 453 394 13.87 11.87 11.21 10.37 10.73 10.28 12.31666667 10.46 446 456 430 455.3333333 444 0.807712871 -0.044598275 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000009///alpha-1,6-mannosyltransferase activity+++GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0052917///dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0097502///mannosylation 223775 223775 'Pim3' mRNA 2907.94 3026.97 2901 67.17 68.84 71.08 44.7 45.12 46.99 69.03 45.60333333 2225.99 2193.98 2264.96 2945.303333 2228.31 2.94E-10 -0.414672812 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 223776 223776 'Selenoo' mRNA 898.56 884.72 231.21 20.67 20.04 5.64 4.66 11.94 10.38 15.45 8.993333333 232.98 582.72 502.32 671.4966667 439.34 0.488687341 -0.590308593 GO:0005694///chromosome+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0070733///protein adenylyltransferase activity GO:0018117///protein adenylylation 22378 22378 'Wbp2' mRNA 9887 10089 8973 311.26 313.08 299.9 202.51 203.23 193.63 308.08 199.79 7385 7239 6842 9649.666667 7155.333333 2.06E-17 -0.441611484 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding+++GO:0031490///chromatin DNA binding "GO:0032570///response to progesterone+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0043627///response to estrogen+++GO:0045184///establishment of protein localization+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050847///progesterone receptor signaling pathway+++GO:0071391///cellular response to estrogen stimulus+++GO:0071442///positive regulation of histone H3-K14 acetylation" 223780 223780 'Adm2' mRNA 3 4 8 0.14 0.18 0.4 0.16 0.17 0.17 0.24 0.166666667 4 4 4 5 4 0.826670417 -0.351863698 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005576///extracellular region GO:0005179///hormone activity+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0006468///protein phosphorylation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007586///digestion+++GO:0007631///feeding behavior+++GO:0010628///positive regulation of gene expression+++GO:0045766///positive regulation of angiogenesis+++GO:0045776///negative regulation of blood pressure 22379 22379 'Fmnl3' mRNA 323 308 226 3.95 3.69 2.94 3.33 3.81 4.1 3.526666667 3.746666667 308 345 365 285.6666667 339.3333333 0.175865041 0.243897354 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0032794///GTPase activating protein binding+++GO:0051015///actin filament binding GO:0001525///angiogenesis+++GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0008360///regulation of cell shape+++GO:0016043///cellular component organization+++GO:0016477///cell migration+++GO:0022604///regulation of cell morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization 22380 22380 'Wbp4' mRNA 804.95 837.01 871.04 12.69 12.98 14.57 13.71 12.54 12.48 13.41333333 12.91 1001 894 882.08 837.6666667 925.6933333 0.261667063 0.129970542 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0070064///proline-rich region binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome" 22381 22381 'Tceal9' mRNA 2606 2820 2648 162.96 174.37 175.7 263.63 301.12 268.94 171.01 277.8966667 4834 5382 4766 2691.333333 4994 2.66E-34 0.881142467 GO:0005634///nucleus GO:0050699///WW domain binding 223827 223827 'Gxylt1' mRNA 379 410 304 3.03 3.25 2.61 3.55 2.75 3.17 2.963333333 3.156666667 507 384 438 364.3333333 443 0.080427111 0.27302946 00514///Other types of O-glycan biosynthesis GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035252///UDP-xylosyltransferase activity" GO:0016266///O-glycan processing 223828 223828 'Pphln1' mRNA 443.09 541.6 351.41 6.25 7.45 5.28 6.95 6.2 6.9 6.326666667 6.683333333 580.12 507.93 563.91 445.3666667 550.6533333 0.043678554 0.300000865 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol "GO:0031424///keratinization+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0097355///protein localization to heterochromatin" 223838 223838 'Adamts20' mRNA 107 119 89 0.93 0.98 0.7 1.28 1.22 1.16 0.87 1.22 202 167 188 105 185.6666667 1.29E-04 0.813353411 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0009967///positive regulation of signal transduction+++GO:0030198///extracellular matrix organization+++GO:0043066///negative regulation of apoptotic process+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0048070///regulation of developmental pigmentation 22384 22384 'Eif4h' mRNA 8175 8742 8069 185.05 194.86 193.72 160.17 158.57 154.67 191.21 157.8033333 8128 7862 7596 8328.666667 7862 0.1114337 -0.09477679 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0033592///RNA strand annealing activity+++GO:0034057///RNA strand-exchange activity+++GO:0043024///ribosomal small subunit binding GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0019953///sexual reproduction+++GO:0048589///developmental growth+++GO:0097010///eukaryotic translation initiation factor 4F complex assembly 223843 223843 'Dbx2' mRNA 68 74 65 1.99 2.04 1.97 1.03 0.69 0.85 2 0.856666667 37 29 31 69 32.33333333 0.001742685 -1.10553218 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22385 22385 'Baz1b' mRNA 2353 2274 2027 18.53 17.74 16.94 26.96 26.2 25.79 17.73666667 26.31666667 3855 3648 3563 2218 3688.666667 1.18E-30 0.723704931 GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin+++GO:0016604///nuclear body+++GO:0043596///nuclear replication fork GO:0000166///nucleotide binding+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035173///histone kinase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0006333///chromatin assembly or disassembly+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation 223864 223864 'Rapgef3' mRNA 3552 3695 3424 52.99 53.34 54.86 35.49 32.33 33.07 53.73 33.63 2749 2550 2509 3557 2602.666667 5.36E-14 -0.462458029 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04670///Leukocyte transendothelial migration+++04720///Long-term potentiation+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031090///organelle membrane+++GO:0031526///brush border membrane+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0097470///ribbon synapse+++GO:1990794///basolateral part of cell+++GO:1990795///rod bipolar cell terminal bouton+++GO:1990796///photoreceptor cell terminal bouton GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030552///cAMP binding+++GO:0044325///ion channel binding GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0008306///associative learning+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0032486///Rap protein signal transduction+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0045793///positive regulation of cell size+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046827///positive regulation of protein export from nucleus+++GO:0050790///regulation of catalytic activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion+++GO:0061028///establishment of endothelial barrier+++GO:0071320///cellular response to cAMP+++GO:1901985///positive regulation of protein acetylation+++GO:1904426///positive regulation of GTP binding+++GO:1904427///positive regulation of calcium ion transmembrane transport+++GO:1904453///positive regulation of potassium:proton exchanging ATPase activity+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000251///positive regulation of actin cytoskeleton reorganization 223870 223870 'Senp1' mRNA 691 634 477 5.39 4.84 4.01 3.63 3.64 3.77 4.746666667 3.68 526 520 533 600.6666667 526.3333333 0.169994983 -0.196219383 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016929///SUMO-specific protease activity+++GO:0070139///SUMO-specific endopeptidase activity+++GO:0070140///SUMO-specific isopeptidase activity GO:0006508///proteolysis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007275///multicellular organism development+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0016926///protein desumoylation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097190///apoptotic signaling pathway 22388 22388 'Wdr1' mRNA 5960 6291 5954 109.54 113.79 116.08 130.91 137.17 134.35 113.1366667 134.1433333 8195 8386 8143 6068.333333 8241.333333 1.52E-14 0.430116971 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0043209///myelin sheath GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0002446///neutrophil mediated immunity+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0030042///actin filament depolymerization+++GO:0030043///actin filament fragmentation+++GO:0030220///platelet formation+++GO:0030834///regulation of actin filament depolymerization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030865///cortical cytoskeleton organization+++GO:0040011///locomotion+++GO:0042247///establishment of planar polarity of follicular epithelium+++GO:0043297///apical junction assembly+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0045214///sarcomere organization+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1990266///neutrophil migration 223881 223881 'Rnd1' mRNA 173.01 146.6 146 4.43 3.69 3.96 3.07 3.42 3.52 4.026666667 3.336666667 138 150 153 155.2033333 147 0.752913831 -0.08662187 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005102///signaling receptor binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007162///negative regulation of cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016322///neuron remodeling+++GO:0016477///cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization 22390 22390 'Wee1' mRNA 227 270 203 3.63 4.23 3.44 3.43 4.16 3.94 3.766666667 3.843333333 248 292 276 233.3333333 272 0.264718922 0.214953278 04110///Cell cycle+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0048812///neuron projection morphogenesis+++GO:0051301///cell division 223917 223917 'Krt79' mRNA 0 3 0 0 0.08 0 0 0 0 0.026666667 0 0 0 0 1 0 0.659075281 -2.407827175 GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0019899///enzyme binding 223918 223918 'Spryd3' mRNA 2584 2588 2086 59.19 58.37 50.7 25.14 25.4 25.54 56.08666667 25.36 1262 1246 1242 2419.333333 1250 2.96E-35 -0.960266192 GO:0005737///cytoplasm GO:0007010///cytoskeleton organization+++GO:0007166///cell surface receptor signaling pathway 223920 223920 'Soat2' mRNA 42.76 38.38 34.26 1.14 1.01 0.97 1.58 1.59 1.38 1.04 1.516666667 68.29 66.9 57.62 38.46666667 64.27 0.042975489 0.73459342 00100///Steroid biosynthesis+++04979///Cholesterol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0004772///sterol O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0034736///cholesterol O-acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0033344///cholesterol efflux+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0034435///cholesterol esterification+++GO:0042632///cholesterol homeostasis 223921 223921 'Aaas' mRNA 398 462 449 12.62 14.43 15.1 21.27 19.58 18.84 14.05 19.89666667 771 693 661 436.3333333 708.3333333 9.22E-09 0.685115822 03013///Nucleocytoplasmic transport GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031965///nuclear membrane+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0001578///microtubule bundle formation+++GO:0006913///nucleocytoplasmic transport+++GO:0007612///learning+++GO:0009566///fertilization+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0090307///mitotic spindle assembly 223922 223922 'Atf7' mRNA 1704 1689 1499 15.75 16.01 15.48 13.49 11.03 14.13 15.74666667 12.88333333 1860 1378 1747 1630.666667 1661.666667 0.905938796 0.015115688 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0034399///nuclear periphery" "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0035497///cAMP response element binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0038066///p38MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097284///hepatocyte apoptotic process" 22393 22393 'Wfs1' mRNA 2134 2119 2073 32.53 31.77 33.52 22.99 19.66 20.76 32.60666667 21.13666667 1736 1450 1518 2108.666667 1568 2.38E-08 -0.440986705 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle GO:0005516///calmodulin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0048306///calcium-dependent protein binding+++GO:0051117///ATPase binding+++GO:0070628///proteasome binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0003091///renal water homeostasis+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031016///pancreas development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042048///olfactory behavior+++GO:0042593///glucose homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045927///positive regulation of growth+++GO:0050821///protein stabilization+++GO:0050877///nervous system process+++GO:0051247///positive regulation of protein metabolic process+++GO:0051726///regulation of cell cycle+++GO:0051928///positive regulation of calcium ion transport+++GO:0055074///calcium ion homeostasis+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1903892///negative regulation of ATF6-mediated unfolded protein response+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process 223970 223970 'Rmi2' mRNA 29.95 22.48 22.96 0.43 0.32 0.35 0.56 0.69 0.6 0.366666667 0.616666667 44.38 53.74 46.11 25.13 48.07666667 0.026426416 0.961369765 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0033045///regulation of sister chromatid segregation+++GO:0043007///maintenance of rDNA+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 223978 223978 'Cpped1' mRNA 727 688 638 15.02 13.99 14.12 14.12 13.42 14.42 14.37666667 13.98666667 783 726 778 684.3333333 762.3333333 0.195919566 0.144909437 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0008150///biological_process 223989 223989 'Marf1' mRNA 1186 997 774 8.05 6.66 5.57 6.25 4.02 5.07 6.76 5.113333333 1061 667 833 985.6666667 853.6666667 0.193487621 -0.216859764 GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:1903231///mRNA binding involved in posttranscriptional gene silencing+++GO:1905762///CCR4-NOT complex binding GO:0006302///double-strand break repair+++GO:0007143///female meiotic nuclear division+++GO:0010468///regulation of gene expression+++GO:0010923///negative regulation of phosphatase activity+++GO:0016441///posttranscriptional gene silencing+++GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle 224008 224008 'Spidr' mRNA 255.47 282.99 264.59 4.32 4.67 4.74 7.48 6.53 6.96 4.576666667 6.99 515.38 438.76 465.34 267.6833333 473.16 1.93E-09 0.811068581 GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0031334///positive regulation of protein complex assembly+++GO:0070202///regulation of establishment of protein localization to chromosome+++GO:0071479///cellular response to ionizing radiation+++GO:0072711///cellular response to hydroxyurea+++GO:0072757///cellular response to camptothecin+++GO:2000781///positive regulation of double-strand break repair 22401 22401 'Zmat3' mRNA 748.99 782.84 632.71 4.98 5.14 4.46 3.65 3.09 3.04 4.86 3.26 631.03 521.52 510.01 721.5133333 554.1866667 0.001033791 -0.389346553 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0015031///protein transport+++GO:0030308///negative regulation of cell growth+++GO:0040008///regulation of growth+++GO:0043065///positive regulation of apoptotic process 224014 224014 'Fgd4' mRNA 667 652 564 4.2 4.04 3.77 4.44 4.35 4.93 4.003333333 4.573333333 811 777 874 627.6666667 820.6666667 3.52E-04 0.37756694 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0007257///activation of JUN kinase activity+++GO:0008360///regulation of cell shape+++GO:0030032///lamellipodium assembly+++GO:0030035///microspike assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 224019 224019 'Tmem191c' mRNA 921 893 811 39.04 37.35 36.47 10 11.8 9.23 37.62 10.34333333 271 312 242 875 275 7.26E-44 -1.679139592 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 22402 22402 'Ccn4' mRNA 353 437 380 3.74 4.55 4.27 3.69 3.86 3.2 4.186666667 3.583333333 402 410 337 390 383 0.863090843 -0.037173764 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031012///extracellular matrix GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008201///heparin binding GO:0001649///osteoblast differentiation+++GO:0001817///regulation of cytokine production+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0042593///glucose homeostasis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0060348///bone development+++GO:0060548///negative regulation of cell death+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0090303///positive regulation of wound healing 224020 224020 'Pi4ka' mRNA 854 961 886 7.7 8.62 8.53 7.6 7.08 7.35 8.283333333 7.343333333 963 889 921 900.3333333 924.3333333 0.855144756 0.025829254 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019034///viral replication complex+++GO:0030660///Golgi-associated vesicle membrane GO:0000166///nucleotide binding+++GO:0004430///1-phosphatidylinositol 4-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0052742///phosphatidylinositol kinase activity GO:0016310///phosphorylation+++GO:0039694///viral RNA genome replication+++GO:0044803///multi-organism membrane organization+++GO:0046786///viral replication complex formation and maintenance+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling 224022 224022 'Slc7a4' mRNA 1706 1903 1818 38.58 42.22 43.55 15.61 15.44 13.14 41.45 14.73 782 733 650 1809 721.6666667 3.59E-48 -1.339008618 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport 224023 224023 'Klhl22' mRNA 1107.45 1094.67 1112.08 21.97 21.43 23.31 18.96 19.89 19.74 22.23666667 19.53 1079.86 1108.31 1090.5 1104.733333 1092.89 0.824532051 -0.028166986 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005827///polar microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0071889///14-3-3 protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0006513///protein monoubiquitination+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010507///negative regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0030307///positive regulation of cell growth+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051301///cell division+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:1904263///positive regulation of TORC1 signaling 224024 224024 'Scarf2' mRNA 78 92 31 1.26 1.46 0.53 0.82 0.85 1.08 1.083333333 0.916666667 57 58 73 67 62.66666667 0.863090843 -0.089148573 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005044///scavenger receptor activity GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 22403 22403 'Ccn5' mRNA 10 15 11 0.33 0.48 0.38 3.09 2.7 1.84 0.396666667 2.543333333 109 93 59 12 87 1.81E-11 2.846101506 GO:0002102///podosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding GO:0001558///regulation of cell growth+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0060548///negative regulation of cell death 22404 22404 'Wiz' mRNA 961 920 725 9.74 8.7 7.52 4.65 4.65 5.68 8.653333333 4.993333333 528 530 648 868.6666667 568.6666667 4.96E-07 -0.617418612 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030496///midbody "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0070984///SET domain binding+++GO:1990226///histone methyltransferase binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0050821///protein stabilization 224044 224044 'Cyp2ab1' mRNA 0 0 1 0 0 0.03 0.02 0 0 0.01 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0042738///exogenous drug catabolic process 224045 224045 'Eif2b5' mRNA 1153 1097 438 25.09 23.5 10.11 10.88 14.45 12.8 19.56666667 12.71 575 746 655 896 658.6666667 0.389628636 -0.433331519 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005851///eukaryotic translation initiation factor 2B complex GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031369///translation initiation factor binding GO:0001541///ovarian follicle development+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0007568///aging+++GO:0009408///response to heat+++GO:0009749///response to glucose+++GO:0010226///response to lithium ion+++GO:0014002///astrocyte development+++GO:0014003///oligodendrocyte development+++GO:0021766///hippocampus development+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042552///myelination+++GO:0043065///positive regulation of apoptotic process+++GO:0043434///response to peptide hormone+++GO:0045727///positive regulation of translation+++GO:0045948///positive regulation of translational initiation+++GO:0048708///astrocyte differentiation+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway 224065 224065 'Uts2b' mRNA 3 4 3 0.24 0.32 0.26 0.42 0.22 0.07 0.273333333 0.236666667 6 3 1 3.333333333 3.333333333 0.998591786 -0.017120283 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0097746///regulation of blood vessel diameter 224079 224079 'Atp13a4' mRNA 109 139 159 1.5 1.87 2.72 1.81 1.84 1.83 2.03 1.826666667 146 139 138 135.6666667 141 0.898191653 0.038013958 GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006812///cation transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 224088 224088 'Atp13a3' mRNA 441 483 369 3.18 3.42 2.82 3.88 3.7 3.79 3.14 3.79 616 574 583 431 591 2.37E-04 0.447368429 GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015594///putrescine-importing ATPase activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006812///cation transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0015847///putrescine transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 22409 22409 'Wnt10a' mRNA 15 29 18 0.44 0.83 0.56 0.13 0.13 0.21 0.61 0.156666667 5 5 8 20.66666667 6 0.016457293 -1.789647093 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0048018///receptor ligand activity GO:0001942///hair follicle development+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0014033///neural crest cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0042476///odontogenesis+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0043586///tongue development+++GO:0043588///skin development+++GO:0045165///cell fate commitment+++GO:0048730///epidermis morphogenesis+++GO:0048733///sebaceous gland development+++GO:0060070///canonical Wnt signaling pathway+++GO:0071560///cellular response to transforming growth factor beta stimulus 224090 224090 'Tmem44' mRNA 230 219 277 3.69 3.19 4.76 2.97 2.94 2.46 3.88 2.79 222 206 189 242 205.6666667 0.226101595 -0.252824829 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 224092 224092 'Lsg1' mRNA 575 604 543 14.02 14.5 14.03 14.51 15.25 14.38 14.18333333 14.71333333 685 703 657 574 681.6666667 0.033926536 0.23772127 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0000054///ribosomal subunit export from nucleus+++GO:0015031///protein transport+++GO:0051168///nuclear export 224093 224093 'Fam43a' mRNA 1808 1755 1504 32.24 30.8 28.45 24.81 24.63 26.79 30.49666667 25.41 1601 1552 1674 1689 1609 0.402172777 -0.078819642 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 224098 224098 'Gm536' mRNA 1 2.02 1 0.09 0.19 0.1 0.57 0.08 0.25 0.126666667 0.3 7 1 3 1.34 3.666666667 0.453326517 1.441263477 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 22410 22410 'Wnt10b' mRNA 1 1 1 0.03 0.02 0.03 0.02 0.02 0.05 0.026666667 0.03 1 1 2 1 1.333333333 0.880628352 0.404396795 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002062///chondrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0007224///smoothened signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0014835///myoblast differentiation involved in skeletal muscle regeneration+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045165///cell fate commitment+++GO:0045598///regulation of fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048641///regulation of skeletal muscle tissue development+++GO:0048741///skeletal muscle fiber development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050821///protein stabilization+++GO:0050909///sensory perception of taste+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051246///regulation of protein metabolic process+++GO:0051726///regulation of cell cycle+++GO:0051885///positive regulation of timing of anagen+++GO:0060070///canonical Wnt signaling pathway+++GO:0060346///bone trabecula formation+++GO:0061196///fungiform papilla development+++GO:0071310///cellular response to organic substance+++GO:0071320///cellular response to cAMP+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071425///hematopoietic stem cell proliferation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis 224105 224105 'Pak2' mRNA 1832 1942 1862 16.96 17.67 18.28 21.85 19.09 21.23 17.63666667 20.72333333 2718 2320 2558 1878.666667 2532 2.69E-08 0.417253206 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05170///Human immunodeficiency virus 1 infection+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0034333///adherens junction assembly+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0046777///protein autophosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050770///regulation of axonogenesis+++GO:0051493///regulation of cytoskeleton organization+++GO:0051497///negative regulation of stress fiber assembly+++GO:0060996///dendritic spine development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070830///bicellular tight junction assembly+++GO:0071407///cellular response to organic cyclic compound+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001271///negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 224109 224109 'Nrros' mRNA 3592.72 3620.03 3425.5 55.25 54.75 55.92 71.92 71.81 74.09 55.30666667 72.60666667 5330.29 5183.39 5311.24 3546.083333 5274.973333 1.10E-24 0.561602963 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0050431///transforming growth factor beta binding GO:0006801///superoxide metabolic process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0014005///microglia development+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0035583///sequestering of TGFbeta in extracellular matrix+++GO:0036364///transforming growth factor beta1 activation+++GO:0045087///innate immune response 22411 22411 'Wnt11' mRNA 21 20 22 0.61 0.53 0.66 0.3 0.16 0.27 0.6 0.243333333 10 6 10 21 8.666666667 0.059317297 -1.293455824 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0005096///GTPase activator activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity "GO:0001649///osteoblast differentiation+++GO:0001822///kidney development+++GO:0001837///epithelial to mesenchymal transition+++GO:0003138///primary heart field specification+++GO:0003139///secondary heart field specification+++GO:0003151///outflow tract morphogenesis+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0003402///planar cell polarity pathway involved in axis elongation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030282///bone mineralization+++GO:0030308///negative regulation of cell growth+++GO:0030325///adrenal gland development+++GO:0030335///positive regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0031667///response to nutrient levels+++GO:0032147///activation of protein kinase activity+++GO:0032915///positive regulation of transforming growth factor beta2 production+++GO:0034394///protein localization to cell surface+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045165///cell fate commitment+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048341///paraxial mesoderm formation+++GO:0048570///notochord morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048844///artery morphogenesis+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060021///roof of mouth development+++GO:0060028///convergent extension involved in axis elongation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060197///cloacal septation+++GO:0060412///ventricular septum morphogenesis+++GO:0060484///lung-associated mesenchyme development+++GO:0060548///negative regulation of cell death+++GO:0060675///ureteric bud morphogenesis+++GO:0060775///planar cell polarity pathway involved in gastrula mediolateral intercalation+++GO:0061053///somite development+++GO:0061101///neuroendocrine cell differentiation+++GO:0062009///secondary palate development+++GO:0070830///bicellular tight junction assembly+++GO:0071260///cellular response to mechanical stimulus+++GO:0072177///mesonephric duct development+++GO:0072201///negative regulation of mesenchymal cell proliferation+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090082///positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090272///negative regulation of fibroblast growth factor production" 224111 224111 'Ubxn7' mRNA 324 312.02 341 4.92 4.67 5.03 5.55 4.87 5.58 4.873333333 5.333333333 432.94 391.11 414.05 325.6733333 412.7 0.02439181 0.325853607 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding GO:0008150///biological_process 22412 22412 'Wnt9b' mRNA 8 5.02 4 0.08 0.05 0.04 0.01 0.02 0.01 0.056666667 0.013333333 1 2 1 5.673333333 1.333333333 0.17100502 -2.088318126 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:1990851///Wnt-Frizzled-LRP5/6 complex GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0039706///co-receptor binding+++GO:0048018///receptor ligand activity "GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0001932///regulation of protein phosphorylation+++GO:0003339///regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009267///cellular response to starvation+++GO:0009786///regulation of asymmetric cell division+++GO:0009887///animal organ morphogenesis+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0030539///male genitalia development+++GO:0035150///regulation of tube size+++GO:0043085///positive regulation of catalytic activity+++GO:0045165///cell fate commitment+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0060021///roof of mouth development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060993///kidney morphogenesis+++GO:0061038///uterus morphogenesis+++GO:0072003///kidney rudiment formation+++GO:0072038///mesenchymal stem cell maintenance involved in nephron morphogenesis+++GO:0072044///collecting duct development+++GO:0072046///establishment of planar polarity involved in nephron morphogenesis+++GO:0072078///nephron tubule morphogenesis+++GO:0072164///mesonephric tubule development+++GO:0072170///metanephric tubule development+++GO:0072174///metanephric tubule formation+++GO:0072181///mesonephric duct formation+++GO:1902455///negative regulation of stem cell population maintenance+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1905438///non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation" 224129 224129 'Adcy5' mRNA 76 117 94 0.84 1.25 1.04 1.2 1.25 1.29 1.043333333 1.246666667 126 135 134 95.66666667 131.6666667 0.089967551 0.450923899 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05012///Parkinson disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0045111///intermediate filament cytoskeleton+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008179///adenylate cyclase binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding GO:0001973///adenosine receptor signaling pathway+++GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007195///adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007626///locomotory behavior+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0050885///neuromuscular process controlling balance+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:1904322///cellular response to forskolin 22413 22413 'Wnt2' mRNA 8 14 5 0.26 0.45 0.17 0.88 0.53 0.59 0.293333333 0.666666667 33 20 21 9 24.66666667 0.031836418 1.450701633 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0048018///receptor ligand activity GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0033278///cell proliferation in midbrain+++GO:0045165///cell fate commitment+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0055009///atrial cardiac muscle tissue morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060070///canonical Wnt signaling pathway+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060492///lung induction+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061180///mammary gland epithelium development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1904954///canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 224132 224132 'Slc49a4' mRNA 227 253 214 2.24 2.45 2.24 2.51 2.18 2.26 2.31 2.316666667 294 249 256 231.3333333 266.3333333 0.30007037 0.192203278 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle 224139 224139 'Golgb1' mRNA 3588 3595 3514 16.91 16.66 17.56 12.7 12.77 12.71 17.04333333 12.72666667 3099 3044 3002 3565.666667 3048.333333 1.56E-04 -0.238312223 GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0035988///chondrocyte proliferation+++GO:1905793///protein localization to pericentriolar material 22414 22414 'Wnt2b' mRNA 817 726 761 12.42 10.86 12.27 10.83 9.6 11.54 11.85 10.65666667 820 710 846 768 792 0.846632005 0.031015256 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding GO:0002062///chondrocyte differentiation+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0008584///male gonad development+++GO:0009267///cellular response to starvation+++GO:0009887///animal organ morphogenesis+++GO:0016055///Wnt signaling pathway+++GO:0021871///forebrain regionalization+++GO:0030182///neuron differentiation+++GO:0045165///cell fate commitment+++GO:0060070///canonical Wnt signaling pathway+++GO:0060492///lung induction+++GO:0060638///mesenchymal-epithelial cell signaling+++GO:0071425///hematopoietic stem cell proliferation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis 224143 224143 'Poglut1' mRNA 1368 1499 1374 26.19 28.27 27.87 21.28 21.03 23.94 27.44333333 22.08333333 1278 1226 1391 1413.666667 1298.333333 0.160069467 -0.134047818 00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0012505///endomembrane system "GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity+++GO:0046527///glucosyltransferase activity" GO:0001756///somitogenesis+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0008593///regulation of Notch signaling pathway+++GO:0010470///regulation of gastrulation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0048318///axial mesoderm development+++GO:0048339///paraxial mesoderm development+++GO:0060537///muscle tissue development+++GO:0072359///circulatory system development 22415 22415 'Wnt3' mRNA 125 155.98 155 2.83 3.3 3.19 0.45 0.58 0.54 3.106666667 0.523333333 19 33 34 145.3266667 28.66666667 1.44E-14 -2.349806312 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0031012///extracellular matrix GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0048018///receptor ligand activity GO:0000902///cell morphogenesis+++GO:0001707///mesoderm formation+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007411///axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009948///anterior/posterior axis specification+++GO:0009950///dorsal/ventral axis specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0044338///canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation+++GO:0044339///canonical Wnt signaling pathway involved in osteoblast differentiation+++GO:0045165///cell fate commitment+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0048697///positive regulation of collateral sprouting in absence of injury+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050767///regulation of neurogenesis+++GO:0060064///Spemann organizer formation at the anterior end of the primitive streak+++GO:0060070///canonical Wnt signaling pathway+++GO:0060173///limb development+++GO:0060174///limb bud formation+++GO:0060323///head morphogenesis+++GO:0061180///mammary gland epithelium development+++GO:0072089///stem cell proliferation+++GO:1904954///canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation+++GO:1905474///canonical Wnt signaling pathway involved in stem cell proliferation 22416 22416 'Wnt3a' mRNA 1 2 2 0.02 0.04 0.04 0 0 0 0.033333333 0 0 0 0 1.666666667 0 0.324592415 -3.197419472 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0009986///cell surface+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:1990851///Wnt-Frizzled-LRP5/6 complex+++GO:1990909///Wnt signalosome GO:0003713///transcription coactivator activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0039706///co-receptor binding+++GO:0048018///receptor ligand activity "GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001947///heart looping+++GO:0002092///positive regulation of receptor internalization+++GO:0003136///negative regulation of heart induction by canonical Wnt signaling pathway+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007498///mesoderm development+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010387///COP9 signalosome assembly+++GO:0010628///positive regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0021527///spinal cord association neuron differentiation+++GO:0021766///hippocampus development+++GO:0021846///cell proliferation in forebrain+++GO:0021874///Wnt signaling pathway involved in forebrain neuroblast division+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0022008///neurogenesis+++GO:0030097///hemopoiesis+++GO:0030168///platelet activation+++GO:0030182///neuron differentiation+++GO:0030198///extracellular matrix organization+++GO:0030509///BMP signaling pathway+++GO:0030879///mammary gland development+++GO:0030890///positive regulation of B cell proliferation+++GO:0030901///midbrain development+++GO:0032092///positive regulation of protein binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033278///cell proliferation in midbrain+++GO:0034613///cellular protein localization+++GO:0035914///skeletal muscle cell differentiation+++GO:0036342///post-anal tail morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045165///cell fate commitment+++GO:0045595///regulation of cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048103///somatic stem cell division+++GO:0048337///positive regulation of mesodermal cell fate specification+++GO:0048343///paraxial mesodermal cell fate commitment+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0048697///positive regulation of collateral sprouting in absence of injury+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050768///negative regulation of neurogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050807///regulation of synapse organization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060070///canonical Wnt signaling pathway+++GO:0060923///cardiac muscle cell fate commitment+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061184///positive regulation of dermatome development+++GO:0061317///canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment+++GO:0062009///secondary palate development+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0070527///platelet aggregation+++GO:0071542///dopaminergic neuron differentiation+++GO:0090245///axis elongation involved in somitogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090676///calcium ion transmembrane transport via low voltage-gated calcium channel+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1901215///negative regulation of neuron death+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904339///negative regulation of dopaminergic neuron differentiation+++GO:1905606///regulation of presynapse assembly+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:2000081///positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2001141///regulation of RNA biosynthetic process" 22417 22417 'Wnt4' mRNA 94.9 116.53 127.09 1.34 1.62 1.91 0.89 0.72 1.05 1.623333333 0.886666667 72 57.11 82.59 112.84 70.56666667 0.016934549 -0.692759355 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04919///Thyroid hormone signaling pathway+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0003714///transcription corepressor activity+++GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity "GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001838///embryonic epithelial tube formation+++GO:0001889///liver development+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007548///sex differentiation+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009267///cellular response to starvation+++GO:0010629///negative regulation of gene expression+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0016055///Wnt signaling pathway+++GO:0022407///regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030237///female sex determination+++GO:0030325///adrenal gland development+++GO:0030336///negative regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0032349///positive regulation of aldosterone biosynthetic process+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033077///T cell differentiation in thymus+++GO:0033080///immature T cell proliferation in thymus+++GO:0035239///tube morphogenesis+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0038030///non-canonical Wnt signaling pathway via MAPK cascade+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042445///hormone metabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045165///cell fate commitment+++GO:0045596///negative regulation of cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048599///oocyte development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048856///anatomical structure development+++GO:0051145///smooth muscle cell differentiation+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0060070///canonical Wnt signaling pathway+++GO:0060126///somatotropin secreting cell differentiation+++GO:0060129///thyroid-stimulating hormone-secreting cell differentiation+++GO:0060231///mesenchymal to epithelial transition+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0060993///kidney morphogenesis+++GO:0061045///negative regulation of wound healing+++GO:0061180///mammary gland epithelium development+++GO:0061184///positive regulation of dermatome development+++GO:0061205///paramesonephric duct development+++GO:0061369///negative regulation of testicular blood vessel morphogenesis+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0072006///nephron development+++GO:0072033///renal vesicle formation+++GO:0072034///renal vesicle induction+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072164///mesonephric tubule development+++GO:0072174///metanephric tubule formation+++GO:0072210///metanephric nephron development+++GO:0072273///metanephric nephron morphogenesis+++GO:2000019///negative regulation of male gonad development+++GO:2000066///positive regulation of cortisol biosynthetic process+++GO:2000180///negative regulation of androgen biosynthetic process+++GO:2000225///negative regulation of testosterone biosynthetic process+++GO:2001234///negative regulation of apoptotic signaling pathway" 224170 224170 'Dzip3' mRNA 590 576 491 5.46 5.16 4.75 3.88 3.89 3.78 5.123333333 3.85 481 465 447 552.3333333 464.3333333 0.035876769 -0.259539882 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0019902///phosphatase binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination 224171 224171 'Cip2a' mRNA 28 44 34 0.38 0.59 0.49 2.05 1.45 1.3 0.486666667 1.6 173 120 105 35.33333333 132.6666667 9.72E-10 1.894626705 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042803///protein homodimerization activity GO:0007283///spermatogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation 22418 22418 'Wnt5a' mRNA 5989 5889 5613 57.41 56.37 57.21 83.04 77.24 82.08 56.99666667 80.78666667 9788 8746 9318 5830.333333 9284 4.54E-35 0.658924132 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005115///receptor tyrosine kinase-like orphan receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:1902379///chemoattractant activity involved in axon guidance "GO:0000187///activation of MAPK activity+++GO:0001667///ameboidal-type cell migration+++GO:0001736///establishment of planar polarity+++GO:0001756///somitogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0001822///kidney development+++GO:0001837///epithelial to mesenchymal transition+++GO:0001843///neural tube closure+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001947///heart looping+++GO:0002009///morphogenesis of an epithelium+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0003138///primary heart field specification+++GO:0003139///secondary heart field specification+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0003323///type B pancreatic cell development+++GO:0003344///pericardium morphogenesis+++GO:0003401///axis elongation+++GO:0003402///planar cell polarity pathway involved in axis elongation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0007442///hindgut morphogenesis+++GO:0007494///midgut development+++GO:0008284///positive regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0009790///embryo development+++GO:0009887///animal organ morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010033///response to organic substance+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0021891///olfactory bulb interneuron development+++GO:0021915///neural tube development+++GO:0022008///neurogenesis+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030324///lung development+++GO:0030326///embryonic limb morphogenesis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030901///midbrain development+++GO:0032092///positive regulation of protein binding+++GO:0032148///activation of protein kinase B activity+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032880///regulation of protein localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034613///cellular protein localization+++GO:0035108///limb morphogenesis+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0036517///chemoattraction of serotonergic neuron axon+++GO:0036518///chemorepulsion of dopaminergic neuron axon+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042060///wound healing+++GO:0042472///inner ear morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043032///positive regulation of macrophage activation+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045165///cell fate commitment+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045778///positive regulation of ossification+++GO:0045807///positive regulation of endocytosis+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046546///development of primary male sexual characteristics+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048341///paraxial mesoderm formation+++GO:0048546///digestive tract morphogenesis+++GO:0048570///notochord morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0048806///genitalia development+++GO:0048812///neuron projection morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048850///hypophysis morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050729///positive regulation of inflammatory response+++GO:0050807///regulation of synapse organization+++GO:0050919///negative chemotaxis+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051216///cartilage development+++GO:0051885///positive regulation of timing of anagen+++GO:0051964///negative regulation of synapse assembly+++GO:0060026///convergent extension+++GO:0060028///convergent extension involved in axis elongation+++GO:0060029///convergent extension involved in organogenesis+++GO:0060065///uterus development+++GO:0060067///cervix development+++GO:0060068///vagina development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060157///urinary bladder development+++GO:0060324///face development+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060599///lateral sprouting involved in mammary gland duct morphogenesis+++GO:0060606///tube closure+++GO:0060638///mesenchymal-epithelial cell signaling+++GO:0060686///negative regulation of prostatic bud formation+++GO:0060744///mammary gland branching involved in thelarche+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0060762///regulation of branching involved in mammary gland duct morphogenesis+++GO:0060775///planar cell polarity pathway involved in gastrula mediolateral intercalation+++GO:0060809///mesodermal to mesenchymal transition involved in gastrulation+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061036///positive regulation of cartilage development+++GO:0061053///somite development+++GO:0061347///planar cell polarity pathway involved in outflow tract morphogenesis+++GO:0061348///planar cell polarity pathway involved in ventricular septum morphogenesis+++GO:0061349///planar cell polarity pathway involved in cardiac right atrium morphogenesis+++GO:0061350///planar cell polarity pathway involved in cardiac muscle tissue morphogenesis+++GO:0061354///planar cell polarity pathway involved in pericardium morphogenesis+++GO:0062009///secondary palate development+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071277///cellular response to calcium ion+++GO:0071346///cellular response to interferon-gamma+++GO:0071425///hematopoietic stem cell proliferation+++GO:0071542///dopaminergic neuron differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0072201///negative regulation of mesenchymal cell proliferation+++GO:0090009///primitive streak formation+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090082///positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090630///activation of GTPase activity+++GO:0097325///melanocyte proliferation+++GO:0099175///regulation of postsynapse organization+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0150012///positive regulation of neuron projection arborization+++GO:1900020///positive regulation of protein kinase C activity+++GO:1901216///positive regulation of neuron death+++GO:1903827///regulation of cellular protein localization+++GO:1904934///negative regulation of cell proliferation in midbrain+++GO:1904938///planar cell polarity pathway involved in axon guidance+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:1904953///Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway" 22419 22419 'Wnt5b' mRNA 113 96 59 2.95 2.51 1.65 2.56 2.34 2.34 2.37 2.413333333 112 99 97.77 89.33333333 102.9233333 0.571683846 0.197503381 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04360///Axon guidance+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding GO:0002062///chondrocyte differentiation+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0042060///wound healing+++GO:0042692///muscle cell differentiation+++GO:0045165///cell fate commitment+++GO:0045600///positive regulation of fat cell differentiation+++GO:0060070///canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904105///positive regulation of convergent extension involved in gastrulation+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway 22420 22420 'Wnt6' mRNA 390 417 376 10.99 11.38 10.94 16.37 16.45 16.73 11.10333333 16.51666667 686 673 669 394.3333333 676 3.65E-12 0.766847638 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0009986///cell surface+++GO:0031012///extracellular matrix GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding "GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009798///axis specification+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045165///cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060070///canonical Wnt signaling pathway+++GO:0060684///epithelial-mesenchymal cell signaling+++GO:0070172///positive regulation of tooth mineralization+++GO:0072079///nephron tubule formation+++GO:0072080///nephron tubule development" 22421 22421 'Wnt7a' mRNA 1132 1259 1223 20.55 22.14 23.64 7.21 5.9 7.21 22.11 6.773333333 461 367 449 1204.666667 425.6666667 1.84E-44 -1.515116646 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity "GO:0000578///embryonic axis specification+++GO:0001502///cartilage condensation+++GO:0001525///angiogenesis+++GO:0002062///chondrocyte differentiation+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007269///neurotransmitter secretion+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009953///dorsal/ventral pattern formation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0014719///skeletal muscle satellite cell activation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0016055///Wnt signaling pathway+++GO:0021707///cerebellar granule cell differentiation+++GO:0021846///cell proliferation in forebrain+++GO:0022009///central nervous system vasculogenesis+++GO:0030010///establishment of cell polarity+++GO:0030182///neuron differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0031133///regulation of axon diameter+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032355///response to estradiol+++GO:0035019///somatic stem cell population maintenance+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043589///skin morphogenesis+++GO:0043627///response to estrogen+++GO:0045165///cell fate commitment+++GO:0045167///asymmetric protein localization involved in cell fate determination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0048103///somatic stem cell division+++GO:0048608///reproductive structure development+++GO:0048705///skeletal system morphogenesis+++GO:0048864///stem cell development+++GO:0050768///negative regulation of neurogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050808///synapse organization+++GO:0051216///cartilage development+++GO:0051965///positive regulation of synapse assembly+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0060065///uterus development+++GO:0060066///oviduct development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060173///limb development+++GO:0060997///dendritic spine morphogenesis+++GO:0061038///uterus morphogenesis+++GO:0062009///secondary palate development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0099175///regulation of postsynapse organization+++GO:1904891///positive regulation of excitatory synapse assembly+++GO:1905606///regulation of presynapse assembly+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential" 22422 22422 'Wnt7b' mRNA 1792 1962 886 28.76 30.99 14.87 12.1 17.84 17.25 24.87333333 15.73 873 1249 1199 1546.666667 1107 0.262043356 -0.47354816 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity+++GO:1902379///chemoattractant activity involved in axon guidance GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0001944///vasculature development+++GO:0003338///metanephros morphogenesis+++GO:0007257///activation of JUN kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0016332///establishment or maintenance of polarity of embryonic epithelium+++GO:0021846///cell proliferation in forebrain+++GO:0021871///forebrain regionalization+++GO:0022009///central nervous system vasculogenesis+++GO:0030182///neuron differentiation+++GO:0030324///lung development+++GO:0031175///neuron projection development+++GO:0032364///oxygen homeostasis+++GO:0032536///regulation of cell projection size+++GO:0036516///chemoattraction of dopaminergic neuron axon+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042592///homeostatic process+++GO:0044237///cellular metabolic process+++GO:0045165///cell fate commitment+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0046330///positive regulation of JNK cascade+++GO:0048144///fibroblast proliferation+++GO:0048568///embryonic organ development+++GO:0048812///neuron projection morphogenesis+++GO:0048864///stem cell development+++GO:0050768///negative regulation of neurogenesis+++GO:0050808///synapse organization+++GO:0051145///smooth muscle cell differentiation+++GO:0060033///anatomical structure regression+++GO:0060070///canonical Wnt signaling pathway+++GO:0060425///lung morphogenesis+++GO:0060428///lung epithelium development+++GO:0060482///lobar bronchus development+++GO:0060484///lung-associated mesenchyme development+++GO:0060535///trachea cartilage morphogenesis+++GO:0060560///developmental growth involved in morphogenesis+++GO:0060669///embryonic placenta morphogenesis+++GO:0060710///chorio-allantoic fusion+++GO:0061180///mammary gland epithelium development+++GO:0071300///cellular response to retinoic acid+++GO:0072053///renal inner medulla development+++GO:0072054///renal outer medulla development+++GO:0072060///outer medullary collecting duct development+++GO:0072061///inner medullary collecting duct development+++GO:0072089///stem cell proliferation+++GO:0072205///metanephric collecting duct development+++GO:0072207///metanephric epithelium development+++GO:0072236///metanephric loop of Henle development+++GO:1902262///apoptotic process involved in blood vessel morphogenesis+++GO:1904938///planar cell polarity pathway involved in axon guidance 224224 224224 'Impg2' mRNA 761.1 710.87 552.08 3.16 2.92 2.41 1.32 0.92 1.09 2.83 1.11 369.46 253.53 297 674.6833333 306.6633333 2.81E-15 -1.147648256 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0033165///interphotoreceptor matrix+++GO:0042995///cell projection+++GO:0043235///receptor complex GO:0005201///extracellular matrix structural constituent+++GO:0005540///hyaluronic acid binding+++GO:0008201///heparin binding GO:0007601///visual perception+++GO:0008104///protein localization+++GO:0008150///biological_process+++GO:0030198///extracellular matrix organization+++GO:0060042///retina morphogenesis in camera-type eye 22423 22423 'Wnt8b' mRNA 1 1 0 0.02 0.02 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity+++GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0045165///cell fate commitment+++GO:0060070///canonical Wnt signaling pathway 224250 224250 'Cldnd1' mRNA 1617 1638 1698 41.76 41.63 46.44 38.05 40 39.22 43.27666667 39.09 1696 1740 1688 1651 1708 0.749787559 0.035772271 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 22427 22427 'Wrn' mRNA 283 256 226 2.34 2.09 1.98 2.39 2.17 2.35 2.136666667 2.303333333 332 295 316 255 314.3333333 0.074407785 0.291857164 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0016607///nuclear speck+++GO:0043005///neuron projection" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000400///four-way junction DNA binding+++GO:0000403///Y-form DNA binding+++GO:0000405///bubble DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0003824///catalytic activity+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008408///3'-5' exonuclease activity+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0030145///manganese ion binding+++GO:0032405///MutLalpha complex binding+++GO:0042803///protein homodimerization activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0061749///forked DNA-dependent helicase activity+++GO:0061821///telomeric D-loop binding+++GO:0070337///3'-flap-structured DNA binding+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006259///DNA metabolic process+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0007569///cell aging+++GO:0008152///metabolic process+++GO:0009267///cellular response to starvation+++GO:0010225///response to UV-C+++GO:0010259///multicellular organism aging+++GO:0031297///replication fork processing+++GO:0032508///DNA duplex unwinding+++GO:0040009///regulation of growth rate+++GO:0042981///regulation of apoptotic process+++GO:0044237///cellular metabolic process+++GO:0044806///G-quadruplex DNA unwinding+++GO:0051345///positive regulation of hydrolase activity+++GO:0061820///telomeric D-loop disassembly+++GO:0071480///cellular response to gamma radiation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090399///replicative senescence+++GO:0098530///positive regulation of strand invasion+++GO:1902570///protein localization to nucleolus 224273 224273 'Crybg3' mRNA 473.65 412.09 341.72 2.41 2.06 1.85 2.34 1.75 1.81 2.106666667 1.966666667 526.85 385.48 396.54 409.1533333 436.29 0.686252067 0.082057087 GO:0032991///protein-containing complex GO:0005212///structural constituent of eye lens+++GO:0030246///carbohydrate binding+++GO:0051018///protein kinase A binding GO:0002088///lens development in camera-type eye+++GO:0007601///visual perception 22428 22428 'Dctn6' mRNA 1286 1341 1202 66.82 71.31 68.65 67.7 72.6 71.09 68.92666667 70.46333333 1437 1492 1452 1276.333333 1460.333333 0.027781 0.184332768 04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex" GO:0003824///catalytic activity+++GO:0070840///dynein complex binding GO:0007005///mitochondrion organization+++GO:0007052///mitotic spindle organization+++GO:0008610///lipid biosynthetic process 224291 224291 'Csnka2ip' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus GO:0005515///protein binding GO:0008150///biological_process 22431 22431 'Wt1' mRNA 30 43 27 0.53 0.75 0.51 0.22 0.25 0.25 0.596666667 0.24 14 16 16 33.33333333 15.33333333 0.034969734 -1.124384891 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0044729///hemi-methylated DNA-binding+++GO:0046872///metal ion binding+++GO:0070742///C2H2 zinc finger domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001570///vasculogenesis+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001823///mesonephros development+++GO:0003156///regulation of animal organ formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007356///thorax and anterior abdomen determination+++GO:0007507///heart development+++GO:0007530///sex determination+++GO:0008285///negative regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0008406///gonad development+++GO:0008584///male gonad development+++GO:0009888///tissue development+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030308///negative regulation of cell growth+++GO:0030317///flagellated sperm motility+++GO:0030325///adrenal gland development+++GO:0030539///male genitalia development+++GO:0030855///epithelial cell differentiation+++GO:0032835///glomerulus development+++GO:0032836///glomerular basement membrane development+++GO:0035802///adrenal cortex formation+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060009///Sertoli cell development+++GO:0060231///mesenchymal to epithelial transition+++GO:0060421///positive regulation of heart growth+++GO:0060539///diaphragm development+++GO:0060923///cardiac muscle cell fate commitment+++GO:0060976///coronary vasculature development+++GO:0061032///visceral serous pericardium development+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0072015///glomerular visceral epithelial cell development+++GO:0072075///metanephric mesenchyme development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0072166///posterior mesonephric tubule development+++GO:0072278///metanephric comma-shaped body morphogenesis+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0072302///negative regulation of metanephric glomerular mesangial cell proliferation+++GO:0072520///seminiferous tubule development+++GO:1900212///negative regulation of mesenchymal cell apoptotic process involved in metanephros development+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1905643///positive regulation of DNA methylation+++GO:2000020///positive regulation of male gonad development+++GO:2000195///negative regulation of female gonad development+++GO:2001076///positive regulation of metanephric ureteric bud development" 22433 22433 'Xbp1' mRNA 7304 7775 7432 182.96 191.85 197.5 346.24 355.47 341.32 190.77 347.6766667 15892 15930 15165 7503.666667 15662.33333 2.55E-83 1.049562178 04141///Protein processing in endoplasmic reticulum+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0098793///presynapse "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0002020///protease binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001558///regulation of cell growth+++GO:0001889///liver development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001935///endothelial cell proliferation+++GO:0002070///epithelial cell maturation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006629///lipid metabolic process+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0008284///positive regulation of cell proliferation+++GO:0009410///response to xenobiotic stimulus+++GO:0010506///regulation of autophagy+++GO:0010508///positive regulation of autophagy+++GO:0010832///negative regulation of myotube differentiation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031017///exocrine pancreas development+++GO:0031062///positive regulation of histone methylation+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0031670///cellular response to nutrient+++GO:0032008///positive regulation of TOR signaling+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032869///cellular response to insulin stimulus+++GO:0034599///cellular response to oxidative stress+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035356///cellular triglyceride homeostasis+++GO:0035470///positive regulation of vascular wound healing+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0042149///cellular response to glucose starvation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045579///positive regulation of B cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048666///neuron development+++GO:0051602///response to electrical stimulus+++GO:0055089///fatty acid homeostasis+++GO:0055092///sterol homeostasis+++GO:0060096///serotonin secretion, neurotransmission+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060612///adipose tissue development+++GO:0060691///epithelial cell maturation involved in salivary gland development+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071230///cellular response to amino acid stimulus+++GO:0071332///cellular response to fructose stimulus+++GO:0071333///cellular response to glucose stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071498///cellular response to fluid shear stress+++GO:0071499///cellular response to laminar fluid shear stress+++GO:1900100///positive regulation of plasma cell differentiation+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1901985///positive regulation of protein acetylation+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903489///positive regulation of lactation+++GO:1990418///response to insulin-like growth factor stimulus+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2000353///positive regulation of endothelial cell apoptotic process" 224344 224344 'Rbm11' mRNA 36 34.38 30.45 0.99 0.84 0.66 0.78 1.15 0.71 0.83 0.88 43.99 30.81 35.53 33.61 36.77666667 0.863090843 0.09885168 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0042803///protein homodimerization activity "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0034599///cellular response to oxidative stress" 22436 22436 'Xdh' mRNA 186 180 187 2.16 2.06 2.45 11.79 11.63 11.15 2.223333333 11.52333333 1123 1087 1038 184.3333333 1082.666667 3.40E-110 2.541761799 00230///Purine metabolism+++00232///Caffeine metabolism+++00983///Drug metabolism - other enzymes+++04146///Peroxisome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0016529///sarcoplasmic reticulum "GO:0004854///xanthine dehydrogenase activity+++GO:0004855///xanthine oxidase activity+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0030151///molybdenum ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050421///nitrite reductase (NO-forming) activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0070674///hypoxanthine dehydrogenase activity+++GO:0070675///hypoxanthine oxidase activity+++GO:0071949///FAD binding" GO:0000255///allantoin metabolic process+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006147///guanine catabolic process+++GO:0006148///inosine catabolic process+++GO:0006149///deoxyinosine catabolic process+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process+++GO:0006161///deoxyguanosine catabolic process+++GO:0006196///AMP catabolic process+++GO:0006204///IMP catabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007595///lactation+++GO:0009114///hypoxanthine catabolic process+++GO:0009115///xanthine catabolic process+++GO:0010044///response to aluminum ion+++GO:0010629///negative regulation of gene expression+++GO:0016226///iron-sulfur cluster assembly+++GO:0030856///regulation of epithelial cell differentiation+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0046038///GMP catabolic process+++GO:0046055///dGMP catabolic process+++GO:0046059///dAMP catabolic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2001213///negative regulation of vasculogenesis 22437 22437 'Xirp1' mRNA 1 1 3 0.01 0.01 0.03 0.05 0.02 0.09 0.016666667 0.053333333 6 3 12 1.666666667 7 0.150680963 2.039766176 GO:0001725///stress fiber+++GO:0005912///adherens junction+++GO:0005916///fascia adherens+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0030054///cell junction GO:0003779///actin binding+++GO:0031005///filamin binding+++GO:0051015///actin filament binding GO:0003007///heart morphogenesis+++GO:0007015///actin filament organization+++GO:0007219///Notch signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0030036///actin cytoskeleton organization+++GO:0032091///negative regulation of protein binding+++GO:0042391///regulation of membrane potential+++GO:0045214///sarcomere organization+++GO:0055013///cardiac muscle cell development 22439 22439 'Xk' mRNA 155 198 144 1.64 2.06 1.62 1.09 0.99 1.06 1.773333333 1.046666667 119 105 112 165.6666667 112 0.010967031 -0.573053265 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006865///amino acid transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0008361///regulation of cell size+++GO:0010961///cellular magnesium ion homeostasis+++GO:0031133///regulation of axon diameter+++GO:0042552///myelination+++GO:0048741///skeletal muscle fiber development 224405 224405 'Cyyr1' mRNA 71 61 74 0.64 0.54 0.71 1.21 0.84 0.79 0.63 0.946666667 154 104 97 68.66666667 118.3333333 0.008442806 0.766209394 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 22441 22441 'Xlr' mRNA 41.62 24.98 39.42 2.58 1.53 2.8 4.08 3.03 4.13 2.303333333 3.746666667 77.07 47.38 72.04 35.34 65.49666667 0.026183524 0.893690971 GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus GO:0003674///molecular_function "GO:0007286///spermatid development+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0051321///meiotic cell cycle" 224419 224419 'Map3k7cl' mRNA 4 3 6 0.22 0.1 0.23 0.18 0.13 0.06 0.183333333 0.123333333 6 3 2 4.333333333 3.666666667 0.863090843 -0.27274269 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 224432 224432 'Scaf4' mRNA 1265.66 1219.69 786.63 13.1 12.41 7.89 5.89 8.35 7.6 11.13333333 7.28 702.61 878.43 809.46 1090.66 796.8333333 0.001797706 -0.452844345 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008022///protein C-terminus binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding "GO:0006397///mRNA processing+++GO:2000805///negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled" 224440 224440 'Setd4' mRNA 145 140 145 3.45 3.57 3.78 1.91 2.17 2.58 3.6 2.22 88 84 104 143.3333333 92 0.006249583 -0.652423423 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0042800///histone methyltransferase activity (H3-K4 specific) GO:0006954///inflammatory response+++GO:0018023///peptidyl-lysine trimethylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0032259///methylation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034773///histone H4-K20 trimethylation+++GO:0044648///histone H3-K4 dimethylation+++GO:0050729///positive regulation of inflammatory response+++GO:0071863///regulation of cell proliferation in bone marrow+++GO:0097692///histone H3-K4 monomethylation 22445 22445 'Xlr3a' mRNA 75.27 90.66 78.46 2.7 3.16 3.15 2.22 1.35 2.05 3.003333333 1.873333333 70.92 41.24 63.83 81.46333333 58.66333333 0.147190623 -0.495980201 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 224454 224454 'Zdhhc14' mRNA 121.7 125.95 132.67 1.95 2.36 2.7 2.34 1.91 2.29 2.336666667 2.18 136.03 126.11 120.41 126.7733333 127.5166667 0.998591786 8.55E-04 04391///Hippo signaling pathway - fly GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation 22446 22446 'Xlr3c' mRNA 23.97 14.04 16.81 0.88 0.51 0.66 0.34 0.21 0.17 0.683333333 0.24 10.63 6.55 5.23 18.27333333 7.47 0.081238406 -1.35070415 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis 224480 224480 'Nox3' mRNA 917 952 962 29.51 30.19 32.84 5.43 3.99 5.27 30.84666667 4.896666667 194 139 182 943.6666667 171.6666667 3.42E-80 -2.473689703 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043020///NADPH oxidase complex GO:0005515///protein binding+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016491///oxidoreductase activity GO:0001659///temperature homeostasis+++GO:0006952///defense response+++GO:0009590///detection of gravity+++GO:0009629///response to gravity+++GO:0042554///superoxide anion generation+++GO:0048840///otolith development 224481 224481 'Tfb1m' mRNA 208.66 216.75 234.76 7.89 7.84 9.14 6.37 5.47 6.22 8.29 6.02 192.12 159.32 191.37 220.0566667 180.9366667 0.145335751 -0.295387926 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid "GO:0000179///rRNA (adenine-N6,N6-)-dimethyltransferase activity+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0034246///mitochondrial sequence-specific DNA-binding transcription factor activity" GO:0000154///rRNA modification+++GO:0006364///rRNA processing+++GO:0006391///transcription initiation from mitochondrial promoter+++GO:0031167///rRNA methylation+++GO:0032259///methylation 224530 224530 'Acat3' mRNA 66.63 66.33 71.21 1.78 1.79 2.01 3.13 3.21 3.11 1.86 3.15 130 130.98 125.13 68.05666667 128.7033333 3.20E-04 0.90997783 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00650///Butanoate metabolism+++00900///Terpenoid backbone biosynthesis+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++04975///Fat digestion and absorption" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006635///fatty acid beta-oxidation 224585 224585 'Zfp160' mRNA 282 366 300 4.02 5.13 4.54 4.24 3.75 3.91 4.563333333 3.966666667 342 296 306 316 314.6666667 0.933598677 -0.01725942 05168///Herpes simplex virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004252///serine-type endopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070009///serine-type aminopeptidase activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030193///regulation of blood coagulation+++GO:0031639///plasminogen activation+++GO:0051919///positive regulation of fibrinolysis" 224598 224598 'Zfp758' mRNA 419 429.82 425 7.28 7.21 7.65 4.37 3.9 4.25 7.38 4.173333333 297 259 282 424.6066667 279.3333333 7.39E-06 -0.616513022 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 224613 224613 'Flywch1' mRNA 3429.3 3563.58 3133.8 50 51.58 48.76 32.16 30.39 29.99 50.11333333 30.84666667 2503.21 2332.05 2313.83 3375.56 2383.03 7.41E-17 -0.512787329 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 224617 224617 'Tbc1d24' mRNA 269.53 336.12 284.63 1.89 2.31 2.08 2.25 2 2.13 2.093333333 2.126666667 369.9 322.64 337.24 296.76 343.26 0.239579781 0.198120526 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0005096///GTPase activator activity GO:0007274///neuromuscular synaptic transmission+++GO:0016358///dendrite development+++GO:0031175///neuron projection development+++GO:0036466///synaptic vesicle recycling via endosome+++GO:0036475///neuron death in response to oxidative stress+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0061564///axon development+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2001224///positive regulation of neuron migration 224619 224619 'Traf7' mRNA 1644 1623 1541 33.76 32.86 33.56 33.67 32.19 34.83 33.39333333 33.56333333 1878 1756 1883 1602.666667 1839 0.014274273 0.186865735 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000027///ribosomal large subunit assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000185///activation of MAPKKK activity+++GO:0006915///apoptotic process+++GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0033235///positive regulation of protein sumoylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0071354///cellular response to interleukin-6+++GO:2001235///positive regulation of apoptotic signaling pathway 224624 224624 'Rab40c' mRNA 229 271 208 5.18 6.04 4.99 4.76 4.81 5.83 5.403333333 5.133333333 242 239 287 236 256 0.615038667 0.109634042 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0072659///protein localization to plasma membrane 224630 224630 'Bnip1' mRNA 307 220 276 16.62 11.72 15.9 17.98 18.54 20.74 14.74666667 19.08666667 368 369 406 267.6666667 381 0.003327663 0.495376142 04130///SNARE interactions in vesicular transport GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030137///COPI-coated vesicle+++GO:0031201///SNARE complex+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005484///SNAP receptor activity "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006915///apoptotic process+++GO:0007029///endoplasmic reticulum organization+++GO:0014823///response to activity+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0042594///response to starvation+++GO:0061025///membrane fusion+++GO:0090649///response to oxygen-glucose deprivation" 224640 224640 'Lemd2' mRNA 381 401 380 8.15 8.45 8.62 7.48 7.01 6.72 8.406666667 7.07 402 368 350 387.3333333 373.3333333 0.714659907 -0.065520693 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0031490///chromatin DNA binding GO:0006998///nuclear envelope organization+++GO:0022008///neurogenesis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035914///skeletal muscle cell differentiation+++GO:0043409///negative regulation of MAPK cascade+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060914///heart formation+++GO:0071168///protein localization to chromatin+++GO:1902531///regulation of intracellular signal transduction 224647 224647 'Ilrun' mRNA 958 1112 942 14.2 16.31 14.92 15.68 14.98 14.76 15.14333333 15.14 1216 1138 1111 1004 1155 0.047270365 0.191618671 GO:0000407///phagophore assembly site+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0043130///ubiquitin binding GO:0002376///immune system process+++GO:0016236///macroautophagy+++GO:0032480///negative regulation of type I interferon production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0043392///negative regulation of DNA binding+++GO:0045087///innate immune response+++GO:0050687///negative regulation of defense response to virus+++GO:1900181///negative regulation of protein localization to nucleus 224648 224648 'Uhrf1bp1' mRNA 582 503 438 3.57 3.03 2.85 2.23 2.02 2.32 3.15 2.19 418 371 423 507.6666667 404 0.014305959 -0.33853254 GO:0005575///cellular_component GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding GO:0008150///biological_process 224650 224650 'Anks1' mRNA 3187.74 3092.35 3048 33.96 32.46 35.95 20.6 20.19 20.75 34.12333333 20.51333333 2137.86 2057 2138 3109.363333 2110.953333 1.03E-18 -0.570913043 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0000287///magnesium ion binding+++GO:0000298///endopolyphosphatase activity+++GO:0008486///diphosphoinositol-polyphosphate diphosphatase activity+++GO:0034431///bis(5'-adenosyl)-hexaphosphatase activity+++GO:0034432///bis(5'-adenosyl)-pentaphosphatase activity+++GO:0046875///ephrin receptor binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0052840///inositol diphosphate tetrakisphosphate diphosphatase activity+++GO:0052842///inositol diphosphate pentakisphosphate diphosphatase activity GO:0006929///substrate-dependent cell migration+++GO:0016322///neuron remodeling+++GO:0048013///ephrin receptor signaling pathway+++GO:0071543///diphosphoinositol polyphosphate metabolic process+++GO:0071544///diphosphoinositol polyphosphate catabolic process+++GO:1901187///regulation of ephrin receptor signaling pathway+++GO:1901907///diadenosine pentaphosphate catabolic process+++GO:1901909///diadenosine hexaphosphate catabolic process+++GO:1901911///adenosine 5'-(hexahydrogen pentaphosphate) catabolic process+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 224656 224656 'Zfp523' mRNA 1299 1381 1062 23.81 24.79 20.93 8.65 8.24 9.55 23.17666667 8.813333333 538 505 571 1247.333333 538 1.41E-33 -1.220423115 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development+++GO:0045944///positive regulation of transcription by RNA polymerase II 224661 224661 'Slc26a8' mRNA 51 47 42 0.87 0.65 0.61 0.2 0.38 0.3 0.71 0.293333333 17 28 25 46.66666667 23.33333333 0.023979466 -1.00596394 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005254///chloride channel activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008272///sulfate transport+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0048240///sperm capacitation+++GO:0051321///meiotic cell cycle+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 224671 224671 'Btbd9' mRNA 2989.58 2969.15 2663.46 21.48 21.34 19.77 10.05 9.32 10.32 20.86333333 9.896666667 1633.96 1507.35 1689.8 2874.063333 1610.37 4.80E-35 -0.84649539 "GO:0007616///long-term memory+++GO:0008344///adult locomotory behavior+++GO:0042428///serotonin metabolic process+++GO:0042748///circadian sleep/wake cycle, non-REM sleep+++GO:0048512///circadian behavior+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050951///sensory perception of temperature stimulus+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:1900242///regulation of synaptic vesicle endocytosis" 224674 224674 'Slc37a1' mRNA 359.21 348.41 317.86 5.74 5.44 5.37 3.93 4.33 4.89 5.516666667 4.383333333 277.1 295.76 340.56 341.8266667 304.4733333 0.304800485 -0.17637699 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity GO:0008643///carbohydrate transport+++GO:0015760///glucose-6-phosphate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0055085///transmembrane transport 224691 224691 'Zfp472' mRNA 135 171 155 3.24 4.04 3.94 4.59 5.02 4.93 3.74 4.846666667 220 235 229 153.6666667 228 0.003715438 0.558005802 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 224694 224694 'Zfp81' mRNA 262 288 257 3.18 3.41 2.97 2.46 2.23 2.26 3.186666667 2.316666667 229 177 198 269 201.3333333 0.014244653 -0.43061761 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 224697 224697 'Adamts10' mRNA 1034 962 995 13.98 12.74 13.99 20.31 18.84 19.29 13.57 19.48 1755 1620 1588 997 1654.333333 6.03E-18 0.717316928 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization 224703 224703 'Marchf2' mRNA 518 533 291 20.81 20.98 11.4 14.18 12.93 14.97 17.73 14.02666667 411 359 410 447.3333333 393.3333333 0.37331432 -0.186246387 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006897///endocytosis+++GO:0016567///protein ubiquitination 224705 224705 'Vps52' mRNA 1801 1932 1766 28.97 30.55 30.12 23.25 23.93 24.57 29.88 23.91666667 1661 1667 1700 1833 1676 0.077906413 -0.140026518 GO:0000938///GARP complex+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:1990745///EARP complex GO:0019905///syntaxin binding "GO:0006896///Golgi to vacuole transport+++GO:0007041///lysosomal transport+++GO:0010668///ectodermal cell differentiation+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048611///embryonic ectodermal digestive tract development" 224727 224727 'Bag6' mRNA 1011 898 640 14.74 12.79 9.77 10.4 9.97 10.44 12.43333333 10.27 828 769 803 849.6666667 800 0.569326204 -0.091464249 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0071818///BAT3 complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030544///Hsp70 protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043022///ribosome binding+++GO:0051787///misfolded protein binding+++GO:0070628///proteasome binding+++GO:1990381///ubiquitin-specific protease binding GO:0001822///kidney development+++GO:0002376///immune system process+++GO:0002429///immune response-activating cell surface receptor signaling pathway+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0007130///synaptonemal complex assembly+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0010498///proteasomal protein catabolic process+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0030101///natural killer cell activation+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0042127///regulation of cell proliferation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045861///negative regulation of proteolysis+++GO:0045995///regulation of embryonic development+++GO:0050821///protein stabilization+++GO:0061857///endoplasmic reticulum stress-induced pre-emptive quality control+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1904294///positive regulation of ERAD pathway+++GO:1904378///maintenance of unfolded protein involved in ERAD pathway 224742 224742 'Abcf1' mRNA 1418 1555 1463 24.64 26.59 26.97 30.31 28.22 29.98 26.06666667 29.50333333 2007 1825 1922 1478.666667 1918 2.63E-06 0.362762083 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0042788///polysomal ribosome "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008494///translation activator activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0043022///ribosome binding" GO:0006413///translational initiation+++GO:0042254///ribosome biogenesis+++GO:0045727///positive regulation of translation 224753 224753 'H2-M10.4' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 224792 224792 'Adgrf5' mRNA 283 323 337 2.14 2.39 2.96 2.34 2.1 2.12 2.496666667 2.186666667 352 312 309 314.3333333 324.3333333 0.879432593 0.029791502 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045177///apical part of cell GO:0003674///molecular_function+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0003094///glomerular filtration+++GO:0006112///energy reserve metabolic process+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019216///regulation of lipid metabolic process+++GO:0042593///glucose homeostasis+++GO:0043031///negative regulation of macrophage activation+++GO:0043129///surfactant homeostasis+++GO:0045444///fat cell differentiation+++GO:0048821///erythrocyte development+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0071073///positive regulation of phospholipid biosynthetic process 224794 224794 'Enpp4' mRNA 1524 1587 1496 18.03 18.46 18.79 10.1 8.92 10.19 18.42666667 9.736666667 983 848 958 1535.666667 929.6666667 1.47E-18 -0.736575776 00230///Purine metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047710///bis(5'-adenosyl)-triphosphatase activity GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030194///positive regulation of blood coagulation+++GO:0046130///purine ribonucleoside catabolic process 224796 224796 'Clic5' mRNA 1834 1893 1772 16.59 16.84 17 3.56 3.47 3.37 16.81 3.466666667 453 431 416 1833 433.3333333 1.17E-132 -2.092346898 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0034707///chloride channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity GO:0002021///response to dietary excess+++GO:0002024///diet induced thermogenesis+++GO:0006749///glutathione metabolic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0008104///protein localization+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0050885///neuromuscular process controlling balance+++GO:0050896///response to stimulus+++GO:0060088///auditory receptor cell stereocilium organization 224805 224805 'Aars2' mRNA 521 462 455 8.68 7.6 7.82 4.7 4.5 3.92 8.033333333 4.373333333 329 298 265 479.3333333 297.3333333 3.54E-07 -0.701095591 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016597///amino acid binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006400///tRNA modification+++GO:0006412///translation+++GO:0006419///alanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0070143///mitochondrial alanyl-tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 224807 224807 'Tmem63b' mRNA 2159 2131 1843 36.41 35.22 32.84 18.81 16.62 18.33 34.82333333 17.92 1282 1106 1210 2044.333333 1199.333333 8.64E-24 -0.77957468 GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005227///calcium activated cation channel activity+++GO:0008381///mechanosensitive ion channel activity+++GO:1990760///osmolarity-sensing cation channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 224813 224813 'Lrrc73' mRNA 528 468 121 22.83 19.97 5.55 0.9 2.05 1.67 16.11666667 1.54 24 53 43 372.3333333 40 4.76E-06 -3.196996614 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 224814 224814 'Abcc10' mRNA 1294.8 1268.47 1158.28 16.57 15.85 15.91 11.14 9.99 10.62 16.11 10.58333333 1012.25 883.75 929.33 1240.516667 941.7766667 2.31E-06 -0.408909371 02010///ABC transporters GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006691///leukotriene metabolic process+++GO:0055085///transmembrane transport+++GO:0071716///leukotriene transport 224823 224823 'Rrp36' mRNA 560.05 648.88 654.99 13.04 14.88 16.12 14.83 16.17 15.08 14.68 15.36 735.12 782.56 722.65 621.3066667 746.7766667 0.040750904 0.252729294 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030686///90S preribosome "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000469///cleavage involved in rRNA processing+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0042274///ribosomal small subunit biogenesis" 224824 224824 'Pex6' mRNA 830 788 429 14.24 13.3 7.81 8.24 7.55 8.62 11.78333333 8.136666667 553 495 560 682.3333333 536 0.058974519 -0.347752624 04146///Peroxisome GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0097733///photoreceptor cell cilium GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding "GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0016558///protein import into peroxisome matrix+++GO:0016561///protein import into peroxisome matrix, translocation+++GO:0050821///protein stabilization" 224826 224826 'Ubr2' mRNA 1570 1586 960 10.85 10.86 7.73 7.2 7.29 7.78 9.813333333 7.423333333 1090 1123 1183 1372 1132 0.04828311 -0.277958744 GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070728///leucine binding GO:0006342///chromatin silencing+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007131///reciprocal meiotic recombination+++GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031507///heterochromatin assembly+++GO:0032007///negative regulation of TOR signaling+++GO:0033522///histone H2A ubiquitination+++GO:0071233///cellular response to leucine+++GO:0071596///ubiquitin-dependent protein catabolic process via the N-end rule pathway 224829 224829 'Trerf1' mRNA 451 365 350 3.24 2.55 2.66 1.4 1.1 1.29 2.816666667 1.263333333 226 173 202 388.6666667 200.3333333 2.37E-09 -0.967777371 GO:0000118///histone deacetylase complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol GO:0001223///transcription coactivator binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0008134///transcription factor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0033142///progesterone receptor binding+++GO:0046872///metal ion binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050847///progesterone receptor signaling pathway+++GO:0071393///cellular response to progesterone stimulus" 224833 224833 'AI661453' mRNA 102 133.72 85.83 1.08 1.4 0.97 0.91 0.63 0.86 1.15 0.8 98.72 67 89.84 107.1833333 85.18666667 0.272321896 -0.340788229 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 224836 224836 'Usp49' mRNA 269 296 117 1.71 1.85 0.79 0.53 0.76 0.73 1.45 0.673333333 96 135 128 227.3333333 119.6666667 0.001386816 -0.916723025 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006325///chromatin organization+++GO:0006397///mRNA processing+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0008380///RNA splicing+++GO:0016579///protein deubiquitination+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination" 224840 224840 'Treml4' mRNA 1 7 10 0.03 0.22 0.36 0.76 0.71 1.09 0.203333333 0.853333333 26 24 37 6 29 0.00167919 2.248300794 GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity "GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002457///T cell antigen processing and presentation+++GO:0006911///phagocytosis, engulfment+++GO:0008104///protein localization+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0034181///positive regulation of toll-like receptor 13 signaling pathway+++GO:0045087///innate immune response+++GO:0051607///defense response to virus" 224860 224860 'Plcl2' mRNA 38 33 36 0.5 0.43 0.51 1.65 1.57 2.01 0.48 1.743333333 143 133 169 35.66666667 148.3333333 9.51E-14 2.043872287 GO:0005737///cytoplasm "GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0050811///GABA receptor binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" "GO:0002322///B cell proliferation involved in immune response+++GO:0002337///B-1a B cell differentiation+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050859///negative regulation of B cell receptor signaling pathway+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900122///positive regulation of receptor binding" 224893 224893 'Zfp959' mRNA 246.97 277.51 292.59 5.65 6.19 7.35 4.88 5.12 5.86 6.396666667 5.286666667 237.24 233.96 250.39 272.3566667 240.53 0.312535346 -0.193196815 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 224897 224897 'Dpp9' mRNA 819 820 728 11.61 11.62 11.29 13.43 13.42 14.83 11.50666667 13.89333333 1022 1020 1117 789 1053 1.64E-05 0.406809511 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0031252///cell leading edge GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis 224902 224902 'Safb2' mRNA 2066.3 2087.11 1979.92 29.94 29.48 30.38 24.76 21.9 23.56 29.93333333 23.40666667 1901.09 1634.13 1844.85 2044.443333 1793.356667 0.010574973 -0.201508661 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0050684///regulation of mRNA processing+++GO:0060008///Sertoli cell differentiation+++GO:0060765///regulation of androgen receptor signaling pathway" 224903 224903 'Safb' mRNA 2129.7 2194.89 2216.08 36.6 37.11 40.39 29.56 29.09 29.47 38.03333333 29.37333333 1979.91 1902.87 1911.15 2180.223333 1931.31 0.015423399 -0.188342332 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030496///midbody GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0040008///regulation of growth+++GO:0042445///hormone metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050684///regulation of mRNA processing" 224904 224904 'Micos13' mRNA 1584 1526 1591 145.76 139.3 155.37 136.59 149.9 142.85 146.81 143.1133333 1698 1814 1714 1567 1742 0.125460104 0.140210744 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044284///mitochondrial crista junction+++GO:0061617///MICOS complex GO:0003674///molecular_function GO:0042407///cristae formation 224907 224907 'Dus3l' mRNA 1091 1078 1093 24.99 24.17 26.51 19.38 17.91 17.29 25.22333333 18.19333333 947 870 826 1087.333333 881 9.38E-04 -0.317098805 GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0017150///tRNA dihydrouridine synthase activity+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding GO:0002943///tRNA dihydrouridine synthesis+++GO:0008033///tRNA processing 224912 224912 'Crb3' mRNA 480 480 420 31.28 31.27 29.25 29.97 30.04 30.41 30.6 30.14 506 485 479 460 490 0.586587905 0.081215504 04530///Tight junction+++05165///Human papillomavirus infection GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0035003///subapical complex+++GO:0045177///apical part of cell GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045216///cell-cell junction organization+++GO:0072659///protein localization to plasma membrane+++GO:1901890///positive regulation of cell junction assembly 224938 224938 'Pja2' mRNA 3373 3735 3601 39.21 42.8 44.42 33.54 34.56 34.05 42.14333333 34.05 3334 3358 3278 3569.666667 3323.333333 0.13210432 -0.115657513 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045111///intermediate filament cytoskeleton+++GO:0045202///synapse GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006954///inflammatory response+++GO:0007616///long-term memory+++GO:0010738///regulation of protein kinase A signaling+++GO:0016567///protein ubiquitination+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0035329///hippo signaling+++GO:0043030///regulation of macrophage activation+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:1900745///positive regulation of p38MAPK cascade 224997 224997 'Dlgap1' mRNA 995.06 938.04 763.07 8.43 8.24 7.11 2.16 2.47 2.61 7.926666667 2.413333333 249 268 287 898.7233333 268 5.48E-47 -1.752190127 04724///Glutamatergic synapse "GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099572///postsynaptic specialization" GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity+++GO:0098919///structural constituent of postsynaptic density GO:0007268///chemical synaptic transmission+++GO:0023052///signaling+++GO:0035418///protein localization to synapse+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070842///aggresome assembly+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099562///maintenance of postsynaptic density structure 225010 225010 'Lclat1' mRNA 624 671 603 7.51 7.92 7.69 5.52 5.4 5.49 7.706666667 5.47 529 506 511 632.6666667 515.3333333 0.006230281 -0.306887046 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006629///lipid metabolic process+++GO:0007275///multicellular organism development+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0036149///phosphatidylinositol acyl-chain remodeling 225020 225020 'Fez2' mRNA 909 973 969 26.08 27.48 29.48 40.2 39.83 37.86 27.68 39.29666667 1598 1549 1459 950.3333333 1535.333333 3.73E-15 0.678873165 GO:0005737///cytoplasm+++GO:0030424///axon GO:0005515///protein binding GO:1902902///negative regulation of autophagosome assembly 225027 225027 'Srsf7' mRNA 3317 3409 3491 74.02 75.39 83.21 68.28 70.7 64.1 77.54 67.69333333 3463 3501 3146 3405.666667 3370 0.780148441 -0.028702017 03040///Spliceosome+++05014///Amyotrophic lateral sclerosis+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0051028///mRNA transport+++GO:1990830///cellular response to leukemia inhibitory factor" 225028 225028 'Map4k3' mRNA 943.7 936.26 1000.49 11.57 11.27 13.02 9.89 9.04 8.75 11.95333333 9.226666667 916.69 818.31 781.86 960.15 838.9533333 0.056736916 -0.210101303 04010///MAPK signaling pathway GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0009411///response to UV+++GO:0016310///phosphorylation+++GO:0034612///response to tumor necrosis factor+++GO:0035556///intracellular signal transduction 225030 225030 'Kcng3' mRNA 102.97 86.67 77.93 0.34 0.29 0.28 0.45 0.46 0.44 0.303333333 0.45 150.41 153.43 147.88 89.19 150.5733333 0.001223721 0.755131789 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 225049 225049 'Ttc7' mRNA 4265 4283 3014 61.7 61.01 46.36 11.04 11.19 11.8 56.35666667 11.34333333 1030 1018 1071 3854 1039.666667 1.95E-88 -1.894301741 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0006879///cellular iron ion homeostasis+++GO:0030097///hemopoiesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 225055 225055 'Fbxo11' mRNA 878 844 891 11.92 11.25 12.78 8.55 8.61 8.35 11.98333333 8.503333333 724 716 681 871 707 0.002628256 -0.314429178 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0046872///metal ion binding GO:0006464///cellular protein modification process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007605///sensory perception of sound+++GO:0016567///protein ubiquitination+++GO:0035246///peptidyl-arginine N-methylation+++GO:0042981///regulation of apoptotic process 225115 225115 'Svil' mRNA 968 1066 970 7.32 7.94 7.82 6.76 5.99 7.05 7.693333333 6.6 1020 889 1028 1001.333333 979 0.73171997 -0.044525393 GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0036449///microtubule minus-end+++GO:0042995///cell projection+++GO:0043034///costamere "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding" GO:0007010///cytoskeleton organization+++GO:0007519///skeletal muscle tissue development+++GO:0008154///actin polymerization or depolymerization+++GO:0032467///positive regulation of cytokinesis+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping 225131 225131 'Wac' mRNA 1473 1287 1175 15.58 13.34 13.31 10.23 9.59 10.32 14.07666667 10.04666667 1112 1016 1082 1311.666667 1070 0.001250153 -0.303725361 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck GO:0000993///RNA polymerase II complex binding+++GO:0003682///chromatin binding "GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010390///histone monoubiquitination+++GO:0010506///regulation of autophagy+++GO:0016239///positive regulation of macroautophagy+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0044783///G1 DNA damage checkpoint+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0071894///histone H2B conserved C-terminal lysine ubiquitination+++GO:1904263///positive regulation of TORC1 signaling" 225152 225152 'Gjd4' mRNA 0 2 1 0 0.04 0.02 0 0 0.02 0.02 0.006666667 0 0 1 1 0.333333333 0.727961753 -1.487412958 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005243///gap junction channel activity GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0014717///regulation of satellite cell activation involved in skeletal muscle regeneration+++GO:0055085///transmembrane transport 225160 225160 'Thoc1' mRNA 507.31 568.04 473.82 12.17 13.48 12.36 13.89 14.12 15.21 12.67 14.40666667 634.5 660.93 668.58 516.39 654.67 0.003888675 0.333028483 03013///Nucleocytoplasmic transport+++03040///Spliceosome "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck" GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000018///regulation of DNA recombination+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0042981///regulation of apoptotic process+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0048297///negative regulation of isotype switching to IgA isotypes+++GO:0051028///mRNA transport+++GO:2000002///negative regulation of DNA damage checkpoint" 225164 225164 'Mib1' mRNA 1349 1425 1146 7.05 7.33 6.3 7.12 5.22 6.44 6.893333333 6.26 1580 1132 1391 1306.666667 1367.666667 0.703094826 0.055080529 05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001841///neural tube formation+++GO:0001947///heart looping+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006897///endocytosis+++GO:0007219///Notch signaling pathway+++GO:0007507///heart development+++GO:0016567///protein ubiquitination+++GO:0045665///negative regulation of neuron differentiation+++GO:0045807///positive regulation of endocytosis 225182 225182 'Rbbp8' mRNA 866 843 872 13.4 12.79 14.24 12.94 12.83 12.87 13.47666667 12.88 966 939 929 860.3333333 944.6666667 0.258452552 0.1217943 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0017053///transcriptional repressor complex+++GO:0035861///site of double-strand break+++GO:0043231///intracellular membrane-bounded organelle GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0000403///Y-form DNA binding+++GO:0000406///double-strand/single-strand DNA junction binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070336///flap-structured DNA binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001835///blastocyst hatching+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010792///DNA double-strand break processing involved in repair via single-strand annealing+++GO:0032355///response to estradiol+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 225187 225187 'Ankrd29' mRNA 62 60 48 1.1 0.96 0.8 0.41 0.45 0.42 0.953333333 0.426666667 29 30 28 56.66666667 29 0.012189322 -0.973837029 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 225207 225207 'Zfp521' mRNA 1609 1719 1648 5.97 6.53 6.87 2.77 2.63 2.8 6.456666667 2.733333333 901 752 910 1658.666667 854.3333333 7.71E-27 -0.970458243 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment 225215 225215 'Rsl24d1' mRNA 894 856 814 34.63 32.71 33.45 35.85 35.08 39.81 33.59666667 36.91333333 1063 1015 1142 854.6666667 1073.333333 8.09E-04 0.317621087 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0022625///cytosolic large ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:1902626///assembly of large subunit precursor of preribosome 225266 225266 'Klhl14' mRNA 176.4 161 161 2.27 1.99 2.13 0.24 0.33 0.28 2.13 0.283333333 23 29 25 166.1333333 25.66666667 3.90E-22 -2.70398802 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0005515///protein binding 225280 225280 'Ino80c' mRNA 563 544 649 13.36 12.71 16.34 17.41 16.25 15.58 14.13666667 16.41333333 844 769 731 585.3333333 781.3333333 0.001415131 0.399495295 GO:0005634///nucleus+++GO:0031011///Ino80 complex+++GO:0071339///MLL1 complex GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus 225283 225283 'Rprd1a' mRNA 903 865 787 12.25 10.83 10.85 8.5 7.58 8.49 11.31 8.19 698 662 681 851.6666667 680.3333333 7.07E-04 -0.334426184 "GO:0016591///RNA polymerase II, holoenzyme" GO:0000993///RNA polymerase II complex binding+++GO:0042802///identical protein binding GO:0031124///mRNA 3'-end processing+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain 225288 225288 'Fhod3' mRNA 124 86 89 1.1 0.78 0.85 0.38 0.39 0.42 0.91 0.396666667 50 48 51 99.66666667 49.66666667 8.06E-04 -1.015001997 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0030017///sarcomere+++GO:0030018///Z disc GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0030837///negative regulation of actin filament polymerization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0045214///sarcomere organization+++GO:0051639///actin filament network formation+++GO:0055003///cardiac myofibril assembly 225289 225289 'AW554918' mRNA 381.01 404.33 367.35 4.27 3.91 4.25 2.47 1.99 1.87 4.143333333 2.11 272.15 191.35 184.57 384.23 216.0233333 4.11E-07 -0.846377251 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 225326 225326 'Pik3c3' mRNA 2606.49 2468.35 2503.26 21.63 20.04 21.97 23.43 25.01 23.78 21.21333333 24.07333333 3329.2 3468.38 3241.64 2526.033333 3346.406667 1.81E-08 0.393753106 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04136///Autophagy - other+++04140///Autophagy - animal+++04145///Phagosome+++04371///Apelin signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05132///Salmonella infection+++05152///Tuberculosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0034271///phosphatidylinositol 3-kinase complex, class III, type I+++GO:0034272///phosphatidylinositol 3-kinase complex, class III, type II+++GO:0035032///phosphatidylinositol 3-kinase complex, class III+++GO:0044754///autolysosome+++GO:0045335///phagocytic vesicle" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity GO:0000045///autophagosome assembly+++GO:0006468///protein phosphorylation+++GO:0006497///protein lipidation+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0007032///endosome organization+++GO:0007049///cell cycle+++GO:0009267///cellular response to starvation+++GO:0016236///macroautophagy+++GO:0016310///phosphorylation+++GO:0016485///protein processing+++GO:0030242///autophagy of peroxisome+++GO:0032465///regulation of cytokinesis+++GO:0034497///protein localization to phagophore assembly site+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0042149///cellular response to glucose starvation+++GO:0043201///response to leucine+++GO:0045022///early endosome to late endosome transport+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050708///regulation of protein secretion+++GO:0051301///cell division 225339 225339 'Ammecr1l' mRNA 1207 1277 1161 13.61 14.28 14 15.06 14.43 14.31 13.96333333 14.6 1526 1437 1423 1215 1462 0.001479614 0.255712865 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 225341 225341 'Lims2' mRNA 286 302 284 9.61 9.93 10.16 11.91 13.06 14.3 9.9 13.09 413 437 473 290.6666667 441 2.01E-05 0.590769419 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0043066///negative regulation of apoptotic process+++GO:0045216///cell-cell junction organization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0098609///cell-cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:2001046///positive regulation of integrin-mediated signaling pathway 225348 225348 'Wdr36' mRNA 515 537 600 8.93 9.06 10.99 11.53 9.85 10.89 9.66 10.75666667 770 655 717 550.6666667 714 0.004258724 0.358171089 03008///Ribosome biogenesis in eukaryotes GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome GO:0001895///retina homeostasis+++GO:0006364///rRNA processing+++GO:0030516///regulation of axon extension 225358 225358 'Fam13b' mRNA 1165.59 1217.86 1247.23 12.69 13.52 14.45 11.79 10.77 11.8 13.55333333 11.45333333 1259.72 1095.44 1205.38 1210.226667 1186.846667 0.736152927 -0.042589907 GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 225362 225362 'Reep2' mRNA 261 243 260 7.75 7.11 8.19 6.61 7.36 6.84 7.683333333 6.936666667 256 278 256 254.6666667 263.3333333 0.863090843 0.035771547 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0008017///microtubule binding+++GO:0031883///taste receptor binding GO:0032386///regulation of intracellular transport+++GO:0032596///protein transport into membrane raft+++GO:0050913///sensory perception of bitter taste+++GO:0050916///sensory perception of sweet taste+++GO:0071786///endoplasmic reticulum tubular network organization 225363 225363 'Etf1' mRNA 839 829 845 12.27 11.91 13.1 22.69 21.6 22.37 12.42666667 22.22 1787 1661 1706 837.6666667 1718 2.18E-36 1.023130256 03015///mRNA surveillance pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0018444///translation release factor complex "GO:0003747///translation release factor activity+++GO:0008079///translation termination factor activity+++GO:0016149///translation release factor activity, codon specific+++GO:1990825///sequence-specific mRNA binding" "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0002184///cytoplasmic translational termination+++GO:0006412///translation+++GO:0006415///translational termination+++GO:0006449///regulation of translational termination+++GO:0006479///protein methylation+++GO:0016032///viral process" 225372 225372 'Apbb3' mRNA 1141 1109 1006.49 33.99 31.98 31.95 15.63 14.54 14.79 32.64 14.98666667 598.13 561.14 570.65 1085.496667 576.64 7.61E-24 -0.923688285 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0001540///amyloid-beta binding+++GO:0008134///transcription factor binding+++GO:0050750///low-density lipoprotein particle receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043066///negative regulation of apoptotic process+++GO:0050714///positive regulation of protein secretion+++GO:1901988///negative regulation of cell cycle phase transition" 225392 225392 'Rell2' mRNA 107.62 90.24 16.16 3.33 2.8 0.46 0.33 0.16 0.25 2.196666667 0.246666667 11.67 7.25 10.59 71.34 9.836666667 1.00E-06 -2.913796722 GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0005518///collagen binding GO:0010811///positive regulation of cell-substrate adhesion+++GO:1900745///positive regulation of p38MAPK cascade 225432 225432 'Rbm27' mRNA 952 903 846 7.84 7.34 7.39 6.98 6.1 7 7.523333333 6.693333333 968 827 947 900.3333333 914 0.939079083 0.010070907 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing 225467 225467 'Pggt1b' mRNA 745 810 729 8.39 8.52 8.23 9.21 7.19 8.17 8.38 8.19 943 775 830 761.3333333 849.3333333 0.204841584 0.14539837 GO:0005953///CAAX-protein geranylgeranyltransferase complex GO:0003824///catalytic activity+++GO:0004659///prenyltransferase activity+++GO:0004661///protein geranylgeranyltransferase activity+++GO:0004662///CAAX-protein geranylgeranyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008318///protein prenyltransferase activity+++GO:0016740///transferase activity+++GO:0036094///small molecule binding+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:1901363///heterocyclic compound binding GO:0008284///positive regulation of cell proliferation+++GO:0018342///protein prenylation+++GO:0018344///protein geranylgeranylation+++GO:0034097///response to cytokine+++GO:0045787///positive regulation of cell cycle+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process 225471 225471 'Ticam2' mRNA 23 23 28 0.38 0.39 0.5 4.08 5.3 4.87 0.423333333 4.75 279 353 324 24.66666667 318.6666667 3.75E-49 3.680398483 04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04620///Toll-like receptor signaling pathway+++05133///Pertussis+++05161///Hepatitis B+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0042995///cell projection+++GO:0045323///interleukin-1 receptor complex GO:0003953///NAD+ nucleosidase activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0046982///protein heterodimerization activity GO:0001817///regulation of cytokine production+++GO:0002376///immune system process+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0007030///Golgi organization+++GO:0007165///signal transduction+++GO:0032648///regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0035669///TRAM-dependent toll-like receptor 4 signaling pathway+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0070671///response to interleukin-12+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071650///negative regulation of chemokine (C-C motif) ligand 5 production+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:2000494///positive regulation of interleukin-18-mediated signaling pathway 225518 225518 'Prdm6' mRNA 0 3 0 0 0.08 0 0 0 0.04 0.026666667 0.013333333 0 0 2 1 0.666666667 0.892724276 -0.547772576 00310///Lysine degradation GO:0005634///nucleus GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0010468///regulation of gene expression+++GO:0016571///histone methylation+++GO:0022008///neurogenesis+++GO:0032259///methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051151///negative regulation of smooth muscle cell differentiation" 225523 225523 'Cep120' mRNA 829 805 928 9.63 9.2 11.43 7.84 6.15 7.18 10.08666667 7.056666667 777 595 689 854 687 0.009286206 -0.331903553 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0008022///protein C-terminus binding GO:0000226///microtubule cytoskeleton organization+++GO:0007098///centrosome cycle+++GO:0008283///cell proliferation+++GO:0010825///positive regulation of centrosome duplication+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0022027///interkinetic nuclear migration+++GO:0030953///astral microtubule organization+++GO:0032880///regulation of protein localization+++GO:0032886///regulation of microtubule-based process+++GO:0045724///positive regulation of cilium assembly+++GO:1903724///positive regulation of centriole elongation+++GO:1904951///positive regulation of establishment of protein localization 225579 225579 'Slc27a6' mRNA 15 9 17 0.32 0.19 0.39 0.54 0.53 0.56 0.3 0.543333333 29 28 29 13.66666667 28.66666667 0.07263778 1.04897634 03320///PPAR signaling pathway+++04931///Insulin resistance GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047676///arachidonate-CoA ligase activity+++GO:1901480///oleate transmembrane transporter activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006869///lipid transport+++GO:0015711///organic anion transport+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport 225583 225583 'Minar2' mRNA 3249 3345 3275 99.96 100.91 106.6 22.31 22.99 23.9 102.49 23.06666667 834 835 862 3289.666667 843.6666667 4.30E-164 -1.975467746 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 225594 225594 'Gm4841' mRNA 101.98 97.61 84.98 1.98 1.87 1.75 2.16 1.81 1.99 1.866666667 1.986666667 127.6 104.55 113.8 94.85666667 115.3166667 0.32124156 0.275990273 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 225600 225600 'Pde6a' mRNA 0 4.67 1 0 0.04 0.01 0 0.03 0.09 0.016666667 0.04 0 3 10.17 1.89 4.39 0.504128854 1.394571955 00230///Purine metabolism+++04744///Phototransduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042622///photoreceptor outer segment membrane "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0045494///photoreceptor cell maintenance+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye 225608 225608 'Sh3tc2' mRNA 634 610 669 7.46 7.1 8.59 7.22 6.96 6.44 7.716666667 6.873333333 706 660 609 637.6666667 658.3333333 0.857706554 0.031100991 GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome GO:0005515///protein binding GO:0022011///myelination in peripheral nervous system+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0033157///regulation of intracellular protein transport+++GO:1901184///regulation of ERBB signaling pathway 225609 225609 'Gm9949' mRNA 5 2 2 0.27 0.13 0.07 0.61 1.02 0.63 0.156666667 0.753333333 18 20 14 3 17.33333333 0.004577707 2.523943013 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 225631 225631 'Onecut2' mRNA 10 14 6 0.04 0.05 0.02 0.02 0.01 0.01 0.036666667 0.013333333 5 3 3 10 3.666666667 0.1741165 -1.449301547 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001889///liver development+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002064///epithelial cell development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031016///pancreas development+++GO:0031018///endocrine pancreas development+++GO:0045165///cell fate commitment+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048935///peripheral nervous system neuron development+++GO:0060271///cilium assembly 225638 225638 'Alpk2' mRNA 3 1 0 0.02 0.01 0 0.01 0.03 0.04 0.01 0.026666667 1 4 6 1.333333333 3.666666667 0.462928622 1.478635419 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0003007///heart morphogenesis+++GO:0003308///negative regulation of Wnt signaling pathway involved in heart development+++GO:0006468///protein phosphorylation+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0042981///regulation of apoptotic process+++GO:0055013///cardiac muscle cell development+++GO:1905223///epicardium morphogenesis 225642 225642 'Grp' mRNA 30 35 20 2.07 2.35 1.44 0.45 0.26 0.13 1.953333333 0.28 7 5 2 28.33333333 4.666666667 2.26E-04 -2.606995349 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle+++GO:0034774///secretory granule lumen GO:0005184///neuropeptide hormone activity GO:0007218///neuropeptide signaling pathway+++GO:0035176///social behavior+++GO:0036343///psychomotor behavior+++GO:0043207///response to external biotic stimulus+++GO:0090277///positive regulation of peptide hormone secretion+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 225651 225651 'Mppe1' mRNA 919.86 916.2 769.06 22.28 22.12 19.84 11.99 16.5 14.8 21.41333333 14.43 569.35 769.2 685.25 868.3733333 674.6 0.004194615 -0.369938943 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005654///nucleoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0070971///endoplasmic reticulum exit site GO:0003674///molecular_function+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0034235///GPI anchor binding+++GO:0046872///metal ion binding+++GO:0062050///GPI-mannose ethanolamine phosphate phosphodiesterase activity GO:0006506///GPI anchor biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport 225655 225655 'Prelid3a' mRNA 110 125 133 2.33 2.96 3.37 2.5 2.9 2.66 2.886666667 2.686666667 124 133 121 122.6666667 126 0.9361027 0.024641626 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:1990050///phosphatidic acid transporter activity GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer 225659 225659 'Cep76' mRNA 229 230 235 2.78 2.74 3.02 3.13 3.55 2.77 2.846666667 3.15 297 329 255 231.3333333 293.6666667 0.063539564 0.331992879 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0046599///regulation of centriole replication 225724 225724 'Mapk4' mRNA 313 350 284 3.56 3.9 3.4 1.6 1.63 1.5 3.62 1.576666667 161 160 147 315.6666667 156 4.10E-10 -1.025776457 04657///IL-17 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 225742 225742 'St8sia5' mRNA 184 166 193 6.38 4.84 6.41 3.84 3.54 3.02 5.876666667 3.466666667 142 132 111 181 128.3333333 0.019773036 -0.511839977 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation 225743 225743 'Rnf165' mRNA 35 31 26 0.25 0.22 0.2 0.05 0.1 0.08 0.223333333 0.076666667 8 17 12 30.66666667 12.33333333 0.022651744 -1.317185869 GO:0005634///nucleus+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0007409///axonogenesis+++GO:0008045///motor neuron axon guidance+++GO:0010259///multicellular organism aging+++GO:0030163///protein catabolic process+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0035136///forelimb morphogenesis+++GO:0060173///limb development+++GO:0060384///innervation+++GO:0061061///muscle structure development 225745 225745 'Haus1' mRNA 243.69 219.04 252.99 10.03 9.31 11.21 16.75 16.05 15.43 10.18333333 16.07666667 450.01 415.64 400.23 238.5733333 421.96 3.51E-08 0.810159919 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 225791 225791 'Zadh2' mRNA 926 975 813 14.53 15.2 13.89 12.45 13.13 13.89 14.54 13.15666667 897 932 964 904.6666667 931 0.804205262 0.033012197 GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0036132///13-prostaglandin reductase activity+++GO:0047522///15-oxoprostaglandin 13-oxidase activity GO:0006693///prostaglandin metabolic process+++GO:0045599///negative regulation of fat cell differentiation 225825 225825 'Cd226' mRNA 4 4 3 0.05 0.05 0.04 0.12 0.26 0.12 0.046666667 0.166666667 7 15 9 3.666666667 10.33333333 0.15373154 1.493300779 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0050839///cell adhesion molecule binding GO:0001816///cytokine production+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0002891///positive regulation of immunoglobulin mediated immune response+++GO:0007155///cell adhesion+++GO:0032729///positive regulation of interferon-gamma production+++GO:0033005///positive regulation of mast cell activation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0060369///positive regulation of Fc receptor mediated stimulatory signaling pathway 225845 225845 'Plaat3' mRNA 2691 2699 2514 91.58 88.96 89.29 81.3 84.87 85.9 89.94333333 84.02333333 2492 2416 2418 2634.666667 2442 0.07705825 -0.120662453 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04923///Regulation of lipolysis in adipocytes GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0008970///phospholipase A1 activity+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0007031///peroxisome organization+++GO:0008654///phospholipid biosynthetic process+++GO:0009617///response to bacterium+++GO:0016042///lipid catabolic process+++GO:0030397///membrane disassembly+++GO:0045786///negative regulation of cell cycle+++GO:0046485///ether lipid metabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process+++GO:0070306///lens fiber cell differentiation+++GO:1903008///organelle disassembly+++GO:1904177///regulation of adipose tissue development 225849 225849 'Ppp2r5b' mRNA 1550 1637 1483 31.38 32.79 31.96 17.45 15.75 18.49 32.04333333 17.23 987 869 1020 1556.666667 958.6666667 5.12E-17 -0.710781964 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019888///protein phosphatase regulator activity+++GO:0072542///protein phosphatase activator activity GO:0001932///regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010976///positive regulation of neuron projection development+++GO:0031334///positive regulation of protein complex assembly+++GO:0031952///regulation of protein autophosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0051726///regulation of cell cycle+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071363///cellular response to growth factor stimulus 225861 225861 'Snx32' mRNA 945 902 888 28.21 26.77 28.55 14.34 14.2 14.98 27.84333333 14.50666667 541 520 549 911.6666667 536.6666667 3.33E-15 -0.77637036 04144///Endocytosis GO:0005768///endosome+++GO:0005829///cytosol GO:0035091///phosphatidylinositol binding "GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi" 225870 225870 'Rin1' mRNA 82.62 48.79 50.9 1.09 0.64 0.71 3.74 3.77 3.35 0.813333333 3.62 322.19 312.45 283.4 60.77 306.0133333 6.37E-27 2.339353727 04014///Ras signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0016192///vesicle-mediated transport+++GO:0031914///negative regulation of synaptic plasticity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 225872 225872 'Npas4' mRNA 11.81 8.04 6.16 0.05 0.05 0.03 0.01 0.04 0.07 0.043333333 0.04 3.07 12.86 11.48 8.67 9.136666667 0.961269638 0.060901582 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0098794///postsynapse "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007612///learning+++GO:0007614///short-term memory+++GO:0007616///long-term memory+++GO:0030154///cell differentiation+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0033554///cellular response to stress+++GO:0035176///social behavior+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048167///regulation of synaptic plasticity+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0071229///cellular response to acid chemical+++GO:0071386///cellular response to corticosterone stimulus+++GO:1904862///inhibitory synapse assembly" 225875 225875 'Lrfn4' mRNA 71 76 44 1.34 1.39 0.88 1.39 1.39 1.56 1.203333333 1.446666667 87 83 94 63.66666667 88 0.156048053 0.464111796 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0099151///regulation of postsynaptic density assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 225876 225876 'Kdm2a' mRNA 1498.57 1593.51 1415.93 13.99 14.53 14.01 12.86 10.76 11.96 14.17666667 11.86 1589 1290.83 1419.6 1502.67 1433.143333 0.436131772 -0.080227334 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific) GO:0001701///in utero embryonic development+++GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0030182///neuron differentiation+++GO:0032922///circadian regulation of gene expression+++GO:0033184///positive regulation of histone ubiquitination+++GO:0035264///multicellular organism growth+++GO:0042752///regulation of circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0048511///rhythmic process+++GO:0060563///neuroepithelial cell differentiation+++GO:0070544///histone H3-K36 demethylation 225884 225884 'Gstp3' mRNA 0 1 1 0 0.1 0.11 0.35 0.13 0.61 0.07 0.363333333 4 2 7 0.666666667 4.333333333 0.171171346 2.680592579 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005829///cytosol GO:0004364///glutathione transferase activity GO:0006749///glutathione metabolic process 225887 225887 'Ndufs8' mRNA 2668 2611 2412 227.56 221.19 218.39 229.07 239.1 226.11 222.38 231.4266667 3109 3132 2947 2563.666667 3062.666667 1.86E-04 0.246122427 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain "GO:0003954///NADH dehydrogenase activity+++GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0006979///response to oxidative stress+++GO:0009060///aerobic respiration+++GO:0032981///mitochondrial respiratory chain complex I assembly" 225888 225888 'Kmt5b' mRNA 1396.4 1488.66 1126.09 14.91 15.62 13.1 8.23 8.04 8.18 14.54333333 8.15 879.13 834.45 850.28 1337.05 854.62 3.84E-12 -0.652853279 00310///Lysine degradation "GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0046872///metal ion binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0007517///muscle organ development+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0034772///histone H4-K20 dimethylation+++GO:0034773///histone H4-K20 trimethylation+++GO:0045830///positive regulation of isotype switching+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 22589 22589 'Atrx' mRNA 3440 3620 3342 17.57 18.17 18.11 15.61 14.93 14.93 17.95 15.15666667 3519 3290 3261 3467.333333 3356.666667 0.423095393 -0.0584992 "GO:0000228///nuclear chromosome+++GO:0000779///condensed chromosome, centromeric region+++GO:0000781///chromosome, telomeric region+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0099115///chromosome, subtelomeric region" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015616///DNA translocase activity+++GO:0016787///hydrolase activity+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0070087///chromo shadow domain binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000212///meiotic spindle organization+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0030900///forebrain development+++GO:0031297///replication fork processing+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0035128///post-embryonic forelimb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060009///Sertoli cell development+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0072520///seminiferous tubule development+++GO:0072711///cellular response to hydroxyurea+++GO:1900112///regulation of histone H3-K9 trimethylation+++GO:1901581///negative regulation of telomeric RNA transcription from RNA pol II promoter+++GO:1901582///positive regulation of telomeric RNA transcription from RNA pol II promoter+++GO:1904908///negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric" 225895 225895 'Taf6l' mRNA 432 480 461 10.99 12.05 12.5 10.52 12.8 11.37 11.84666667 11.56333333 474 562 497 457.6666667 511 0.328064759 0.148145114 03022///Basal transcription factors GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0030914///STAGA complex+++GO:0046695///SLIK (SAGA-like) complex GO:0003713///transcription coactivator activity+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046982///protein heterodimerization activity "GO:0006352///DNA-templated transcription, initiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:1904672///regulation of somatic stem cell population maintenance" 225896 225896 'Ubxn1' mRNA 2067 2005 1976 117.24 112.22 119.08 124.6 120.66 115.51 116.18 120.2566667 2501 2375 2227 2016 2367.666667 0.00332247 0.219489847 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0043025///neuronal cell body GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0051117///ATPase binding+++GO:0071796///K6-linked polyubiquitin modification-dependent protein binding+++GO:1904855///proteasome regulatory particle binding GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1903094///negative regulation of protein K48-linked deubiquitination+++GO:1904293///negative regulation of ERAD pathway+++GO:2000157///negative regulation of ubiquitin-specific protease activity 225898 225898 'Eml3' mRNA 1160 1217 1037 20.38 21.18 19.49 18.29 18.48 18.19 20.35 18.32 1193 1177 1145 1138 1171.666667 0.776367474 0.032634561 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0072686///mitotic spindle+++GO:1990498///mitotic spindle microtubule GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0051301///cell division+++GO:1901673///regulation of mitotic spindle assembly 22590 22590 'Xpa' mRNA 416 388 366 28.18 26 26.3 17.2 19.22 20.18 26.82666667 18.86666667 291 317 330 390 312.6666667 0.025483407 -0.32857126 01524///Platinum drug resistance+++03420///Nucleotide excision repair GO:0000110///nucleotide-excision repair factor 1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009411///response to UV+++GO:0009636///response to toxic substance+++GO:0009650///UV protection+++GO:0010506///regulation of autophagy+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0034504///protein localization to nucleus+++GO:0035264///multicellular organism growth+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0070914///UV-damage excision repair+++GO:1901255///nucleotide-excision repair involved in interstrand cross-link repair" 225908 225908 'Myrf' mRNA 14 13 10 0.14 0.13 0.11 0.08 0.05 0.13 0.126666667 0.086666667 9 6 14 12.33333333 9.666666667 0.720256801 -0.359114224 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0014003///oligodendrocyte development+++GO:0016540///protein autoprocessing+++GO:0022010///central nervous system myelination+++GO:0030154///cell differentiation+++GO:0031643///positive regulation of myelination+++GO:0032286///central nervous system myelin maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048709///oligodendrocyte differentiation" 22591 22591 'Xpc' mRNA 736 805 696 10.99 11.82 11.02 7.68 8.81 8.29 11.27666667 8.26 592 663 619 745.6666667 624.6666667 0.019260046 -0.264402516 03420///Nucleotide excision repair GO:0000109///nucleotide-excision repair complex+++GO:0000111///nucleotide-excision repair factor 2 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071942///XPC complex+++GO:0090734///site of DNA damage GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0000720///pyrimidine dimer repair by nucleotide-excision repair+++GO:0006111///regulation of gluconeogenesis+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010224///response to UV-B+++GO:0010996///response to auditory stimulus+++GO:0031573///intra-S DNA damage checkpoint+++GO:0042493///response to drug+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070914///UV-damage excision repair+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:1990731///UV-damage excision repair, DNA incision" 225912 225912 'Cyb561a3' mRNA 856.88 868.75 879.91 19.27 18.59 19.72 24.09 25.56 23 19.19333333 24.21666667 1225.33 1274.56 1139.13 868.5133333 1213.006667 5.79E-07 0.470435828 GO:0005730///nucleolus+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006879///cellular iron ion homeostasis+++GO:0055085///transmembrane transport 225913 225913 'Tkfc' mRNA 255 271 189 5.94 6.14 4.6 4.73 5.15 4.56 5.56 4.813333333 247 256 221 238.3333333 241.3333333 0.959881911 0.012677186 00051///Fructose and mannose metabolism+++00561///Glycerolipid metabolism+++01200///Carbon metabolism+++04622///RIG-I-like receptor signaling pathway GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004371///glycerone kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0034012///FAD-AMP lyase (cyclizing) activity+++GO:0046872///metal ion binding+++GO:0050354///triokinase activity GO:0006071///glycerol metabolic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0019563///glycerol catabolic process+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0044262///cellular carbohydrate metabolic process+++GO:0045088///regulation of innate immune response+++GO:0046835///carbohydrate phosphorylation+++GO:0061624///fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate+++GO:0061625///glycolytic process through fructose-1-phosphate 22592 22592 'Ercc5' mRNA 566 573 548 7.29 7.25 7.53 6.69 6.21 5.78 7.356666667 6.226666667 591 528 491 562.3333333 536.6666667 0.587090607 -0.080038596 03420///Nucleotide excision repair GO:0000109///nucleotide-excision repair complex+++GO:0005634///nucleus+++GO:0005662///DNA replication factor A complex+++GO:0005694///chromosome+++GO:0032991///protein-containing complex "GO:0000405///bubble DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0008047///enzyme activator activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding" "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006285///base-excision repair, AP site formation+++GO:0006289///nucleotide-excision repair+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0009411///response to UV+++GO:0009650///UV protection+++GO:0010225///response to UV-C+++GO:0035264///multicellular organism growth+++GO:0043066///negative regulation of apoptotic process+++GO:0050790///regulation of catalytic activity+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 225922 225922 'Oosp2' mRNA 112 104 104 12.08 11.15 11.91 0.85 1.16 0.69 11.71333333 0.9 9 12 7 106.6666667 9.333333333 1.59E-18 -3.525804628 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 225929 225929 'Patl1' mRNA 486 504 335 6.17 6.26 4.48 4.82 4.54 5.34 5.636666667 4.9 438 402 468 441.6666667 436 0.904839814 -0.023056594 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0030014///CCR4-NOT complex+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0002151///G-quadruplex RNA binding+++GO:0003723///RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0030371///translation repressor activity+++GO:0034046///poly(G) binding GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0017148///negative regulation of translation+++GO:0033962///cytoplasmic mRNA processing body assembly 22594 22594 'Xrcc1' mRNA 2643 2657 2545 60.54 59.94 61.7 29.14 28.34 27.82 60.72666667 28.43333333 1469 1393 1355 2615 1405.666667 1.57E-40 -0.907616892 03410///Base excision repair "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0070522///ERCC4-ERCC1 complex" GO:0003684///damaged DNA binding+++GO:0019899///enzyme binding+++GO:0032356///oxidized DNA binding+++GO:1990599///3' overhang single-stranded DNA endodeoxyribonuclease activity GO:0000012///single strand break repair+++GO:0001666///response to hypoxia+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010033///response to organic substance+++GO:0010836///negative regulation of protein ADP-ribosylation+++GO:0021587///cerebellum morphogenesis+++GO:0021766///hippocampus development+++GO:0033194///response to hydroperoxide+++GO:0042493///response to drug+++GO:0050882///voluntary musculoskeletal movement+++GO:0061819///telomeric DNA-containing double minutes formation+++GO:1903518///positive regulation of single strand break repair+++GO:1904877///positive regulation of DNA ligase activity+++GO:1905765///negative regulation of protection from non-homologous end joining at telomere+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange 22596 22596 'Xrcc5' mRNA 1439 1554 1434 30.85 32.75 32.69 12.94 15.01 13.12 32.09666667 13.69 688 779 675 1475.666667 714 5.32E-30 -1.057756616 03450///Non-homologous end-joining "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0032040///small-subunit processome+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex+++GO:0043564///Ku70:Ku80 complex+++GO:0070419///nonhomologous end joining complex+++GO:0090734///site of DNA damage+++GO:1990904///ribonucleoprotein complex" GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0034511///U3 snoRNA binding+++GO:0042162///telomeric DNA binding+++GO:0044877///protein-containing complex binding+++GO:0045027///DNA end binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity "GO:0000237///leptotene+++GO:0000723///telomere maintenance+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007420///brain development+++GO:0008283///cell proliferation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032508///DNA duplex unwinding+++GO:0034462///small-subunit processome assembly+++GO:0042254///ribosome biogenesis+++GO:0042493///response to drug+++GO:0045087///innate immune response+++GO:0045860///positive regulation of protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0060218///hematopoietic stem cell differentiation+++GO:0071398///cellular response to fatty acid+++GO:0071475///cellular hyperosmotic salinity response+++GO:0071480///cellular response to gamma radiation+++GO:0071481///cellular response to X-ray+++GO:1904430///negative regulation of t-circle formation+++GO:1990830///cellular response to leukemia inhibitory factor" 22598 22598 'Slc6a18' mRNA 4.64 2 0 0.06 0.02 0 0.02 0.02 0.02 0.026666667 0.02 1.99 1.95 2.09 2.213333333 2.01 0.839303607 -0.566811603 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005515///protein binding+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006810///transport+++GO:0006836///neurotransmitter transport+++GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport 22599 22599 'Slc6a20b' mRNA 13 7 14 0.25 0.12 0.25 0.16 0.22 0.15 0.206666667 0.176666667 11 15 10 11.33333333 12 0.94871856 0.063883301 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005298///proline:sodium symporter activity+++GO:0005515///protein binding+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015199///amino-acid betaine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0019900///kinase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006810///transport+++GO:0006865///amino acid transport+++GO:0007165///signal transduction+++GO:0015816///glycine transport+++GO:0015824///proline transport+++GO:0015838///amino-acid betaine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0043029///T cell homeostasis+++GO:0050863///regulation of T cell activation+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:1904271///L-proline import across plasma membrane+++GO:1905647///proline import across plasma membrane 225994 225994 'Nmrk1' mRNA 651.9 681.15 617.24 23.4 23.99 23.47 18.96 19.2 19.22 23.62 19.12666667 610.25 603.98 599.49 650.0966667 604.5733333 0.340417133 -0.115809175 00760///Nicotinate and nicotinamide metabolism GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0050262///ribosylnicotinamide kinase activity+++GO:0061769///ribosylnicotinate kinase activity GO:0009435///NAD biosynthetic process+++GO:0016310///phosphorylation+++GO:0019363///pyridine nucleotide biosynthetic process 225995 225995 'D030056L22Rik' mRNA 366 387 81 13.07 13.63 3.07 2.33 5.83 6.33 9.923333333 4.83 75 183 197 278 151.6666667 0.343893384 -0.849264236 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 225997 225997 'Trpm6' mRNA 51 36 35 0.42 0.29 0.3 0.72 0.45 0.47 0.336666667 0.546666667 57 63 66 40.66666667 62 0.113590768 0.600354004 04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0030001///metal ion transport+++GO:0034220///ion transmembrane transport+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 225998 225998 'Rorb' mRNA 95 96 67 0.52 0.52 0.4 0.16 0.31 0.37 0.48 0.28 34 62 71 86 55.66666667 0.084601058 -0.6275934 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0008502///melatonin receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007601///visual perception+++GO:0030522///intracellular receptor signaling pathway+++GO:0035881///amacrine cell differentiation+++GO:0042462///eye photoreceptor cell development+++GO:0042752///regulation of circadian rhythm+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046548///retinal rod cell development+++GO:0046549///retinal cone cell development+++GO:0048511///rhythmic process+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:0071300///cellular response to retinoic acid" 22601 22601 'Yap1' mRNA 1046 994 849 13.58 12.65 11.69 11.24 9.95 10.87 12.64 10.68666667 998 863 936 963 932.3333333 0.654870453 -0.056412494 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0001674///female germ cell nucleus+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0070064///proline-rich region binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001570///vasculogenesis+++GO:0001824///blastocyst development+++GO:0001829///trophectodermal cell differentiation+++GO:0001894///tissue homeostasis+++GO:0003015///heart process+++GO:0003143///embryonic heart tube morphogenesis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010837///regulation of keratinocyte proliferation+++GO:0030216///keratinocyte differentiation+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030903///notochord development+++GO:0032570///response to progesterone+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035329///hippo signaling+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046622///positive regulation of organ growth+++GO:0048339///paraxial mesoderm development+++GO:0048368///lateral mesoderm development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0050847///progesterone receptor signaling pathway+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060242///contact inhibition+++GO:0060449///bud elongation involved in lung branching+++GO:0060487///lung epithelial cell differentiation+++GO:0060576///intestinal epithelial cell development+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061026///cardiac muscle tissue regeneration+++GO:0065003///protein-containing complex assembly+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071300///cellular response to retinoic acid+++GO:0071480///cellular response to gamma radiation+++GO:0072091///regulation of stem cell proliferation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902018///negative regulation of cilium assembly+++GO:1902459///positive regulation of stem cell population maintenance+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:2000737///negative regulation of stem cell differentiation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 226016 226016 'Abhd17b' mRNA 418 434 351 9.42 9.61 8.39 8.6 6.06 7.08 9.14 7.246666667 439 302 350 401 363.6666667 0.398164099 -0.15226756 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055038///recycling endosome membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099031///anchored component of postsynaptic density membrane+++GO:0099033///anchored component of postsynaptic recycling endosome membrane GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity GO:0002084///protein depalmitoylation+++GO:0099175///regulation of postsynapse organization+++GO:1902473///regulation of protein localization to synapse+++GO:1902817///negative regulation of protein localization to microtubule+++GO:1902950///regulation of dendritic spine maintenance+++GO:1905668///positive regulation of protein localization to endosome 226025 226025 'Trpm3' mRNA 10929 10987 10227 96.08 98.2 91.13 49.89 44.74 50.85 95.13666667 48.49333333 6158 5408 5829 10714.33333 5798.333333 3.73E-64 -0.897845001 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005261///cation channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0016048///detection of temperature stimulus+++GO:0034220///ion transmembrane transport+++GO:0050951///sensory perception of temperature stimulus+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 226026 226026 'Smc5' mRNA 672 670 632 6.2 6.07 6.18 6.67 6.57 6.36 6.15 6.533333333 833 801 767 658 800.3333333 0.00821617 0.271059988 "GO:0000775///chromosome, centromeric region+++GO:0000781///chromosome, telomeric region+++GO:0000803///sex chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030915///Smc5-Smc6 complex+++GO:0035061///interchromatin granule+++GO:0035861///site of double-strand break" GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding+++GO:0016887///ATPase activity "GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0019827///stem cell population maintenance+++GO:0030261///chromosome condensation+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0044772///mitotic cell cycle phase transition+++GO:0051301///cell division+++GO:0051984///positive regulation of chromosome segregation+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0090398///cellular senescence" 226040 226040 'Tmem252' mRNA 299.68 345.61 275.39 6.79 7.71 6.62 15.02 13.91 15.62 7.04 14.85 762.17 689.55 767.47 306.8933333 739.73 7.68E-27 1.261616861 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 226041 226041 'Pgm5' mRNA 824.32 775.39 710.61 5.43 5.02 4.97 2.4 1.87 2.21 5.14 2.16 419.83 319.45 373.53 770.1066667 370.9366667 2.20E-19 -1.067383037 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005914///spot adherens junction+++GO:0005925///focal adhesion+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014704///intercalated disc+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0042383///sarcolemma+++GO:0043034///costamere "GO:0000287///magnesium ion binding+++GO:0004614///phosphoglucomutase activity+++GO:0005515///protein binding+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0007155///cell adhesion+++GO:0014706///striated muscle tissue development+++GO:0030239///myofibril assembly+++GO:0071704///organic substance metabolic process 226043 226043 'Cbwd1' mRNA 147 183 188 4.29 5.26 5.77 5.17 4.01 4.05 5.106666667 4.41 204 154 155 172.6666667 171 0.90945006 -0.031239466 GO:0005737///cytoplasm+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 226075 226075 'Glis3' mRNA 278 262 218 2.14 2.21 1.75 0.57 0.9 0.78 2.033333333 0.75 91 132 103 252.6666667 108.6666667 2.49E-09 -1.222663716 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 22608 22608 'Ybx1' mRNA 4268 4587 748.93 109.1 115.38 20.21 34.67 46.76 58.26 81.56333333 46.56333333 1569.06 2060.92 2542.95 3201.31 2057.643333 0.507005417 -0.615222757 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:1990124///messenger ribonucleoprotein complex+++GO:1990904///ribonucleoprotein complex GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035198///miRNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0051020///GTPase binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0008544///epidermis development+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048255///mRNA stabilization+++GO:0048598///embryonic morphogenesis+++GO:0050658///RNA transport+++GO:0051031///tRNA transport+++GO:0051154///negative regulation of striated muscle cell differentiation+++GO:0051781///positive regulation of cell division+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0098761///cellular response to interleukin-7+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:1990428///miRNA transport+++GO:2000773///negative regulation of cellular senescence" 226089 226089 'Ric1' mRNA 358 327 327 2.75 2.47 2.65 2.37 2.11 2.26 2.623333333 2.246666667 357 309 329 337.3333333 331.6666667 0.861610143 -0.037141978 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding "GO:0003330///regulation of extracellular matrix constituent secretion+++GO:0006886///intracellular protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043547///positive regulation of GTPase activity+++GO:1903363///negative regulation of cellular protein catabolic process+++GO:1904888///cranial skeletal system development" 226090 226090 'Ermp1' mRNA 1057 1237 837 10.43 12.01 8.76 7.07 8.58 7.32 10.4 7.656666667 825 978 827 1043.666667 876.6666667 0.051928835 -0.254796099 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001541///ovarian follicle development+++GO:0006508///proteolysis+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034599///cellular response to oxidative stress 226098 226098 'Hectd2' mRNA 53 47 26 0.41 0.36 0.24 0.26 0.28 0.46 0.336666667 0.333333333 39 43 62 42 48 0.722107328 0.193603458 GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity GO:0016567///protein ubiquitination 226101 226101 'Myof' mRNA 807 764 661 6.03 5.6 5.24 11.06 11.2 10.21 5.623333333 10.82333333 1708 1695 1527 744 1643.333333 1.02E-37 1.134089821 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0001778///plasma membrane repair+++GO:0006071///glycerol metabolic process+++GO:0007009///plasma membrane organization+++GO:0007520///myoblast fusion+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0033292///T-tubule organization+++GO:0034605///cellular response to heat+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0061025///membrane fusion 226105 226105 'Cyp2c70' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 226115 226115 'Opalin' mRNA 0 1 0 0 0.02 0 0 0.02 0 0.006666667 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044291///cell-cell contact zone GO:0003674///molecular_function GO:0048713///regulation of oligodendrocyte differentiation 22612 22612 'Yes1' mRNA 392.94 501.3 388.05 5.11 6.49 5.25 4.47 4.77 3.87 5.616666667 4.37 404.84 422.52 344.88 427.43 390.7466667 0.421922139 -0.139254129 04520///Adherens junction "GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0099091///postsynaptic specialization, intracellular component" GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0044325///ion channel binding GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0010827///regulation of glucose transmembrane transport+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0071300///cellular response to retinoic acid+++GO:0071560///cellular response to transforming growth factor beta stimulus 226122 226122 'Ubtd1' mRNA 1505 1480 1391 60.72 59.4 58.8 37.72 34.6 34.56 59.64 35.62666667 1067 968 958 1458.666667 997.6666667 4.74E-12 -0.559800995 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 226123 226123 'Morn4' mRNA 1476 1580 1400 46.78 49.37 47.07 21.96 23.43 22.4 47.74 22.59666667 796 829 786 1485.333333 803.6666667 5.18E-27 -0.896095551 GO:0005737///cytoplasm+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0032433///filopodium tip+++GO:0042995///cell projection GO:0005515///protein binding GO:0048678///response to axon injury 226139 226139 'Cox15' mRNA 319.68 344.5 360.02 3.57 3.78 4.26 4.78 3.93 4.61 3.87 4.44 492.94 395.85 460.42 341.4 449.7366667 0.00935496 0.381382597 00190///Oxidative phosphorylation+++00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors+++04714///Thermogenesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0070069///cytochrome complex "GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016653///oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor+++GO:0060090///molecular adaptor activity" GO:0006784///heme a biosynthetic process+++GO:0008535///respiratory chain complex IV assembly+++GO:1902600///proton transmembrane transport 226143 226143 'Cyp2c23' mRNA 0 1 0 0 0.04 0 0.03 0 0.08 0.013333333 0.036666667 1 0 3 0.333333333 1.333333333 0.612923478 1.881840792 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0046456///icosanoid biosynthetic process 226144 226144 'Erlin1' mRNA 266 305 273 4.52 5.14 4.95 8.43 8.31 7.88 4.87 8.206666667 565 544 513 281.3333333 540.6666667 2.98E-13 0.931108144 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0031625///ubiquitin protein ligase binding GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032933///SREBP signaling pathway+++GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0045717///negative regulation of fatty acid biosynthetic process 226151 226151 'Slf2' mRNA 1116 1060 948 11.58 10.6 10.17 9.76 8.4 9.33 10.78333333 9.163333333 1065 952 1048 1041.333333 1021.666667 0.755811568 -0.037854102 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break+++GO:0043231///intracellular membrane-bounded organelle GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031334///positive regulation of protein complex assembly+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:1990166///protein localization to site of double-strand break+++GO:2000781///positive regulation of double-strand break repair 226153 226153 'Twnk' mRNA 618.52 570.33 552.58 10.67 9.96 10.31 8.62 9.01 8.1 10.31333333 8.576666667 557.19 551.77 506.83 580.4766667 538.5966667 0.370292081 -0.119684519 05017///Spinocerebellar ataxia GO:0005739///mitochondrion+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0003678///DNA helicase activity+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043139///5'-3' DNA helicase activity GO:0006260///DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006390///mitochondrial transcription+++GO:0032508///DNA duplex unwinding+++GO:0034214///protein hexamerization+++GO:0071333///cellular response to glucose stimulus 226154 226154 'Lzts2' mRNA 2348.39 2309.45 2017.04 46.51 45.17 42.34 31.12 32.98 34.85 44.67333333 32.98333333 1807.67 1870.83 1959.86 2224.96 1879.453333 9.73E-04 -0.252615119 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0030496///midbody+++GO:0031982///vesicle GO:0000281///mitotic cytokinesis+++GO:0001822///kidney development+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0051013///microtubule severing+++GO:0051168///nuclear export+++GO:0051255///spindle midzone assembly+++GO:0051301///cell division+++GO:0060682///primary ureteric bud growth+++GO:0072197///ureter morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900181///negative regulation of protein localization to nucleus 226162 226162 'Dpcd' mRNA 1084 1130 1133 62.39 61.7 68.25 44.65 44.43 44.62 64.11333333 44.56666667 885 879 878 1115.666667 880.6666667 1.36E-04 -0.35409493 GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0005515///protein binding GO:0003351///epithelial cilium movement+++GO:0007283///spermatogenesis+++GO:0007368///determination of left/right symmetry+++GO:0021591///ventricular system development+++GO:0021670///lateral ventricle development+++GO:0021678///third ventricle development+++GO:0030317///flagellated sperm motility+++GO:0060972///left/right pattern formation 226169 226169 'Pprc1' mRNA 269 218 254 2.73 2.2 2.72 5.62 5.53 5.92 2.55 5.69 627 611 654 247 630.6666667 5.99E-24 1.338891886 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0008134///transcription factor binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity" 226178 226178 'Wbp1l' mRNA 1438 1560 1307 19.97 21.3 19.27 25.4 22.89 22.93 20.18 23.74 2116 1859 1848 1435 1941 8.16E-08 0.425356476 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0031625///ubiquitin protein ligase binding GO:0008150///biological_process+++GO:0030097///hemopoiesis+++GO:0031398///positive regulation of protein ubiquitination+++GO:0038160///CXCL12-activated CXCR4 signaling pathway 226180 226180 'Ina' mRNA 134.2 142.52 49 2.25 2.35 0.87 0.09 0.19 0.24 1.823333333 0.173333333 6 13 16 108.5733333 11.66666667 4.14E-12 -3.202830492 GO:0005882///intermediate filament+++GO:0005883///neurofilament+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043209///myelin sheath+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099160///postsynaptic intermediate filament cytoskeleton GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0098973///structural constituent of postsynaptic actin cytoskeleton+++GO:0099184///structural constituent of postsynaptic intermediate filament cytoskeleton GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0060052///neurofilament cytoskeleton organization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0099185///postsynaptic intermediate filament cytoskeleton organization+++GO:1990830///cellular response to leukemia inhibitory factor 226182 226182 'Taf5' mRNA 35 59 52 0.59 0.97 0.92 0.82 0.54 0.77 0.826666667 0.71 56 36 51 48.66666667 47.66666667 0.927393136 -0.046107198 03022///Basal transcription factors GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0015629///actin cytoskeleton+++GO:0033276///transcription factor TFTC complex GO:0003677///DNA binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0042802///identical protein binding+++GO:1990841///promoter-specific chromatin binding "GO:0006352///DNA-templated transcription, initiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0043966///histone H3 acetylation" 22619 22619 'Siae' mRNA 580 737 661 9.3 11.62 11.24 11.63 10.32 10.17 10.72 10.70666667 835 724 707 659.3333333 755.3333333 0.164288534 0.182879134 GO:0005737///cytoplasm+++GO:0005764///lysosome GO:0001681///sialate O-acetylesterase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0002682///regulation of immune system process+++GO:0005975///carbohydrate metabolic process 226245 226245 'Plekhs1' mRNA 186 160 221 4.38 3.67 5.47 12.17 13.04 11.45 4.506666667 12.22 594 627 547 189 589.3333333 1.70E-25 1.623606146 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 22625 22625 'Map3k19' mRNA 45.34 36.18 20.87 0.45 0.33 0.21 0.45 0.19 0.36 0.33 0.333333333 56.93 23.16 46.71 34.13 42.26666667 0.608596619 0.301290523 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 226250 226250 'Afap1l2' mRNA 999 1158 914 13.74 15.7 13.69 12.33 13.82 12.93 14.37666667 13.02666667 1017 1124 1032 1023.666667 1057.666667 0.769474424 0.039739693 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0035591///signaling adaptor activity+++GO:0042169///SH2 domain binding "GO:0006954///inflammatory response+++GO:0007346///regulation of mitotic cell cycle+++GO:0009966///regulation of signal transduction+++GO:0032675///regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061098///positive regulation of protein tyrosine kinase activity" 226251 226251 'Ablim1' mRNA 1961 2013 1820 16.69 16.91 16.5 17.2 14.93 17.35 16.7 16.49333333 2327 1970 2263 1931.333333 2186.666667 0.037869797 0.167484941 04360///Axon guidance GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0007411///axon guidance+++GO:0030032///lamellipodium assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060271///cilium assembly 226252 226252 'Fam160b1' mRNA 868 899 504 8.18 8.32 5.02 4.04 3.1 3.65 7.173333333 3.596666667 492 371 431 757 431.3333333 1.10E-06 -0.813720411 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 226255 226255 'Atrnl1' mRNA 281 229 204 2.28 1.81 1.74 1.73 1.49 1.71 1.943333333 1.643333333 241 207 236 238 228 0.764034651 -0.071326509 GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading 22626 22626 'Slc23a3' mRNA 29 21 22 0.68 0.44 0.58 0.3 0.37 0.28 0.566666667 0.316666667 15 16 17 24 16 0.344228515 -0.594956544 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity GO:0008150///biological_process+++GO:0055085///transmembrane transport 226265 226265 'Eno4' mRNA 793.46 732.44 753.63 13.27 12.5 14.23 1.28 1.21 1.19 13.33333333 1.226666667 130.48 110 118 759.8433333 119.4933333 1.58E-85 -2.683170815 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway GO:0000015///phosphopyruvate hydratase complex+++GO:0097228///sperm principal piece GO:0000287///magnesium ion binding+++GO:0004634///phosphopyruvate hydratase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity "GO:0006096///glycolytic process+++GO:0030317///flagellated sperm motility+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0044782///cilium organization" 22627 22627 'Ywhae' mRNA 9624 9489 8664 261.36 253.79 249.59 261.23 244.92 259.31 254.9133333 255.1533333 11019 10104 10601 9259 10574.66667 4.45E-04 0.180711286 04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04621///NOD-like receptor signaling pathway+++04722///Neurotrophin signaling pathway+++05160///Hepatitis C+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005871///kinesin complex+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0042470///melanosome+++GO:0045202///synapse+++GO:0090724///central region of growth cone+++GO:0098978///glutamatergic synapse GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0050815///phosphoserine residue binding+++GO:0051219///phosphoprotein binding+++GO:0097110///scaffold protein binding GO:0000165///MAPK cascade+++GO:0001764///neuron migration+++GO:0006605///protein targeting+++GO:0007165///signal transduction+++GO:0007346///regulation of mitotic cell cycle+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0034504///protein localization to nucleus+++GO:0034605///cellular response to heat+++GO:0034613///cellular protein localization+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060306///regulation of membrane repolarization+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:1901020///negative regulation of calcium ion transmembrane transporter activity+++GO:1902309///negative regulation of peptidyl-serine dephosphorylation+++GO:1905913///negative regulation of calcium ion export across plasma membrane 22628 22628 'Ywhag' mRNA 1927 1895 1493 29.13 28.18 23.94 45.26 40.69 45.14 27.08333333 43.69666667 3446 3026 3328 1771.666667 3266.666667 1.18E-28 0.874705856 04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04390///Hippo signaling pathway+++05160///Hepatitis C+++05203///Viral carcinogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0043209///myelin sheath+++GO:0045202///synapse+++GO:0098793///presynapse GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding GO:0006605///protein targeting+++GO:0007165///signal transduction+++GO:0032869///cellular response to insulin stimulus+++GO:0034613///cellular protein localization+++GO:0045664///regulation of neuron differentiation+++GO:0048167///regulation of synaptic plasticity 22629 22629 'Ywhah' mRNA 2227 2435 1841 72.95 78.61 63.97 108.99 126.73 127.14 71.84333333 120.9533333 3824 4340 4317 2167.666667 4160.333333 7.86E-29 0.935325146 04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04390///Hippo signaling pathway+++05160///Hepatitis C+++05203///Viral carcinogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017080///sodium channel regulator activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046982///protein heterodimerization activity "GO:0002028///regulation of sodium ion transport+++GO:0006713///glucocorticoid catabolic process+++GO:0006886///intracellular protein transport+++GO:0007010///cytoskeleton organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0007165///signal transduction+++GO:0034613///cellular protein localization+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0086010///membrane depolarization during action potential+++GO:2000649///regulation of sodium ion transmembrane transporter activity" 22630 22630 'Ywhaq' mRNA 5476.78 5820.34 5649.59 146.94 153.82 160.8 155.53 174 163.83 153.8533333 164.4533333 6665.49 7280.02 6795.9 5648.903333 6913.803333 3.87E-05 0.279988147 04013///MAPK signaling pathway - fly+++04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04212///Longevity regulating pathway - worm+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++05160///Hepatitis C+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0004497///monooxygenase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0047485///protein N-terminus binding+++GO:0071889///14-3-3 protein binding "GO:0006605///protein targeting+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0034613///cellular protein localization+++GO:0034766///negative regulation of ion transmembrane transport+++GO:0045892///negative regulation of transcription, DNA-templated" 22631 22631 'Ywhaz' mRNA 10051 9914 9792 166.63 161.91 172.28 201.95 180.18 194.49 166.94 192.2066667 14035 12161 13064 9919 13086.66667 2.06E-11 0.386264836 04013///MAPK signaling pathway - fly+++04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04212///Longevity regulating pathway - worm+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++05160///Hepatitis C+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0002553///histamine secretion by mast cell+++GO:0003016///respiratory system process+++GO:0006468///protein phosphorylation+++GO:0006605///protein targeting+++GO:0006626///protein targeting to mitochondrion+++GO:0007165///signal transduction+++GO:0008039///synaptic target recognition+++GO:0009410///response to xenobiotic stimulus+++GO:0010941///regulation of cell death+++GO:0030324///lung development+++GO:0034613///cellular protein localization+++GO:0035148///tube formation+++GO:0042493///response to drug+++GO:0051683///establishment of Golgi localization+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0090128///regulation of synapse maturation+++GO:0090168///Golgi reassembly 22632 22632 'Yy1' mRNA 558 520 477 5.06 4.63 4.59 4.68 3.92 4.6 4.76 4.4 594 486 565 518.3333333 548.3333333 0.656946667 0.069731058 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005677///chromatin silencing complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0031011///Ino80 complex+++GO:0031519///PcG protein complex "GO:0000400///four-way junction DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006403///RNA localization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0010225///response to UV-C+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0032688///negative regulation of interferon-beta production+++GO:0034644///cellular response to UV+++GO:0034696///response to prostaglandin F+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0048593///camera-type eye morphogenesis+++GO:0051276///chromosome organization+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0071347///cellular response to interleukin-1+++GO:0071707///immunoglobulin heavy chain V-D-J recombination+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II" 22634 22634 'Plagl1' mRNA 169 125 162 1.79 1.32 1.81 1.9 1.48 1.7 1.64 1.693333333 208 157 176 152 180.3333333 0.360238665 0.22900478 GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0035914///skeletal muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 22635 22635 'Zan' mRNA 13.63 13.6 14.09 0.05 0.05 0.05 0.05 0.03 0.02 0.05 0.033333333 14.64 8.77 6.88 13.77333333 10.09666667 0.557445117 -0.533994025 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0050840///extracellular matrix binding GO:0007155///cell adhesion+++GO:0007339///binding of sperm to zona pellucida+++GO:2000359///regulation of binding of sperm to zona pellucida 226351 226351 'Tmem185b' mRNA 394 456 451 7.68 8.75 9.33 12.03 11.48 12.48 8.586666667 11.99666667 710 662 713 433.6666667 695 1.63E-08 0.666865439 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 226352 226352 'Epb41l5' mRNA 2304 2323 2382 21.76 22.9 25.2 14.97 14.24 13.18 23.28666667 14.13 1466 1365 1264 2336.333333 1365 6.12E-23 -0.789436087 GO:0001917///photoreceptor inner segment+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0032587///ruffle membrane GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0019904///protein domain specific binding "GO:0000904///cell morphogenesis involved in differentiation+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001839///neural plate morphogenesis+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0003382///epithelial cell morphogenesis+++GO:0003383///apical constriction+++GO:0006931///substrate-dependent cell migration, cell attachment to substrate+++GO:0007398///ectoderm development+++GO:0007492///endoderm development+++GO:0007498///mesoderm development+++GO:0007509///mesoderm migration involved in gastrulation+++GO:0009826///unidimensional cell growth+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030036///actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032525///somite rostral/caudal axis specification+++GO:0048318///axial mesoderm development+++GO:0048319///axial mesoderm morphogenesis+++GO:0048339///paraxial mesoderm development+++GO:0048617///embryonic foregut morphogenesis+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0070201///regulation of establishment of protein localization+++GO:0070986///left/right axis specification+++GO:0071560///cellular response to transforming growth factor beta stimulus" 226356 226356 'Cfap221' mRNA 37 31 38 0.73 0.65 0.77 0.02 0.09 0.09 0.716666667 0.066666667 1 4 5 35.33333333 3.333333333 1.28E-06 -3.417830213 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0005516///calmodulin binding GO:0003341///cilium movement+++GO:0030030///cell projection organization+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:0090660///cerebrospinal fluid circulation 226359 226359 'C1ql2' mRNA 2 1 0 0.06 0.03 0 0.22 0.13 0.05 0.03 0.133333333 9 5 2 1 5.333333333 0.164359739 2.413336294 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0042802///identical protein binding 22637 22637 'Zap70' mRNA 7 9 8 0.31 0.22 0.21 0.78 0.6 0.6 0.246666667 0.66 29 20 22 8 23.66666667 0.018953405 1.550171774 04014///Ras signaling pathway+++04064///NF-kappa B signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++05135///Yersinia infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05340///Primary immunodeficiency GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042101///T cell receptor complex+++GO:0045121///membrane raft GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006955///immune response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0043366///beta selection+++GO:0045059///positive thymic T cell selection+++GO:0045060///negative thymic T cell selection+++GO:0045061///thymic T cell selection+++GO:0045087///innate immune response+++GO:0045582///positive regulation of T cell differentiation+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0046777///protein autophosphorylation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050852///T cell receptor signaling pathway 22640 22640 'Zfp1' mRNA 373 427 394 9.02 10.18 9.71 8.18 7.46 8.09 9.636666667 7.91 374 309 352 398 345 0.152733657 -0.219194374 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 226407 226407 'Rab3gap1' mRNA 1476 1636 1545 18.78 20.51 20.9 15 16.84 15.67 20.06333333 15.83666667 1351 1481 1373 1552.333333 1401.666667 0.093791381 -0.158502616 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0032991///protein-containing complex+++GO:0060076///excitatory synapse+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098794///postsynapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0007420///brain development+++GO:0010628///positive regulation of gene expression+++GO:0010807///regulation of synaptic vesicle priming+++GO:0021854///hypothalamus development+++GO:0032483///regulation of Rab protein signal transduction+++GO:0034389///lipid droplet organization+++GO:0043010///camera-type eye development+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048489///synaptic vesicle transport+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0060079///excitatory postsynaptic potential+++GO:0060325///face morphogenesis+++GO:0061646///positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization+++GO:0097051///establishment of protein localization to endoplasmic reticulum membrane+++GO:1903061///positive regulation of protein lipidation+++GO:1903233///regulation of calcium ion-dependent exocytosis of neurotransmitter+++GO:1903373///positive regulation of endoplasmic reticulum tubular network organization+++GO:2000786///positive regulation of autophagosome assembly 226409 226409 'Zranb3' mRNA 245.92 248.03 191.69 2.33 2.3 1.99 3.47 3.97 4.56 2.206666667 4 377.34 402.37 468.47 228.5466667 416.06 3.52E-08 0.860121857 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0043596///nuclear replication fork GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003678///DNA helicase activity+++GO:0003824///catalytic activity+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0036310///annealing helicase activity+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0009411///response to UV+++GO:0031297///replication fork processing+++GO:0032508///DNA duplex unwinding+++GO:0036292///DNA rewinding+++GO:0045910///negative regulation of DNA recombination+++GO:0048478///replication fork protection+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 226412 226412 'R3hdm1' mRNA 840 773 843 9.81 8.87 10.46 9.85 8.33 8.42 9.713333333 8.866666667 970 807 806 818.6666667 861 0.69452573 0.057230312 GO:0005575///cellular_component GO:0003676///nucleic acid binding GO:0008150///biological_process 226413 226413 'Lct' mRNA 21 20 25 0.18 0.17 0.23 0.07 0.07 0.06 0.193333333 0.066666667 9 9 8 22 8.666666667 0.041371073 -1.36107094 00052///Galactose metabolism+++04973///Carbohydrate digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000016///lactase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008422///beta-glucosidase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0001666///response to hypoxia+++GO:0005975///carbohydrate metabolic process+++GO:0007584///response to nutrient+++GO:0008152///metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010033///response to organic substance+++GO:0010040///response to iron(II) ion+++GO:0010045///response to nickel cation+++GO:0010288///response to lead ion+++GO:0042493///response to drug+++GO:0045471///response to ethanol 226414 226414 'Dars' mRNA 1392 1467 1518 35.36 36.44 40.75 41.53 45.87 41.74 37.51666667 43.04666667 1874 2027 1837 1459 1912.666667 2.25E-05 0.377504309 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004815///aspartate-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006422///aspartyl-tRNA aminoacylation 226418 226418 'Yod1' mRNA 303.64 306.32 287.08 4.27 4.24 4.29 3.11 3.03 2.94 4.266666667 3.026666667 254.19 242 233.12 299.0133333 243.1033333 0.055143024 -0.309073788 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity "GO:0006508///proteolysis+++GO:0006986///response to unfolded protein+++GO:0016236///macroautophagy+++GO:0016579///protein deubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0035523///protein K29-linked deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol+++GO:1990167///protein K27-linked deubiquitination+++GO:1990168///protein K33-linked deubiquitination" 226419 226419 'Dyrk3' mRNA 317 259 130 8.68 6.98 3.78 1.48 3.37 2.07 6.48 2.306666667 62 138 84 235.3333333 94.66666667 3.45E-05 -1.303512728 GO:0000242///pericentriolar material+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030218///erythrocyte differentiation+++GO:0035063///nuclear speck organization+++GO:0035617///stress granule disassembly+++GO:0043066///negative regulation of apoptotic process+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0051301///cell division+++GO:0080135///regulation of cellular response to stress+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:1903008///organelle disassembly+++GO:1903432///regulation of TORC1 signaling" 22642 22642 'Zbtb17' mRNA 524.5 574.97 574.78 10.43 11.04 11.98 8.45 8.56 10.04 11.15 9.016666667 490.71 495.92 565.95 558.0833333 517.5266667 0.40895239 -0.122025534 04110///Cell cycle+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding" "GO:0001702///gastrulation with mouth forming second+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007398///ectoderm development+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest" 226421 226421 'Rab7b' mRNA 57 101 117 0.73 1.31 1.84 10.38 10.94 9.53 1.293333333 10.28333333 925 863 853 91.66666667 880.3333333 2.89E-76 3.245439492 04137///Mitophagy - animal+++04140///Autophagy - animal+++04145///Phagosome+++05132///Salmonella infection+++05146///Amoebiasis GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0034164///negative regulation of toll-like receptor 9 signaling pathway+++GO:0034499///late endosome to Golgi transport+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071346///cellular response to interferon-gamma+++GO:0090385///phagosome-lysosome fusion 226422 226422 'Rab29' mRNA 311 319 329 16.09 16.3 18.06 47.21 46.89 49.2 16.81666667 47.76666667 1047 1014 1055 319.6666667 1038.666667 6.88E-58 1.687231926 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005773///vacuole+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0020003///symbiont-containing vacuole+++GO:0031982///vesicle+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097708///intracellular vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0019894///kinesin binding+++GO:0031267///small GTPase binding+++GO:0070840///dynein complex binding "GO:0001921///positive regulation of receptor recycling+++GO:0006886///intracellular protein transport+++GO:0007005///mitochondrion organization+++GO:0007030///Golgi organization+++GO:0007416///synapse assembly+++GO:0009617///response to bacterium+++GO:0010977///negative regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030154///cell differentiation+++GO:0032438///melanosome organization+++GO:0039694///viral RNA genome replication+++GO:0042110///T cell activation+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0060271///cilium assembly+++GO:0072657///protein localization to membrane+++GO:0090316///positive regulation of intracellular protein transport+++GO:1901214///regulation of neuron death+++GO:1901998///toxin transport+++GO:1903441///protein localization to ciliary membrane+++GO:1905279///regulation of retrograde transport, endosome to Golgi" 22643 22643 'Zfp101' mRNA 208 212 192 4.21 4.2 4.13 3.2 2.91 3.83 4.18 3.313333333 182 162 212 204 185.3333333 0.511849483 -0.149219777 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 226432 226432 'Ipo9' mRNA 1255 1166 1132 13.46 11.89 12.9 16.82 14.24 15.55 12.75 15.53666667 1815 1542 1607 1184.333333 1654.666667 2.28E-08 0.469836803 03013///Nucleocytoplasmic transport GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0042393///histone binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0007010///cytoskeleton organization+++GO:0007166///cell surface receptor signaling pathway+++GO:0015031///protein transport+++GO:0042254///ribosome biogenesis+++GO:0050821///protein stabilization+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902993///positive regulation of amyloid precursor protein catabolic process 22644 22644 'Rnf103' mRNA 421 404 320 6.99 6.61 5.64 6.05 5.57 5.59 6.413333333 5.736666667 419 375 376 381.6666667 390 0.89764152 0.022927687 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway 226442 226442 'Zfp281' mRNA 699 749 684 7.07 7.45 7.34 7.61 8.06 7.76 7.286666667 7.81 866 896 856 710.6666667 872.6666667 0.004395322 0.285624331 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010172///embryonic body morphogenesis+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation" 22646 22646 'Zfp105' mRNA 351 331 343 9.27 8.12 9.22 3.49 4 4.19 8.87 3.893333333 153 165 168 341.6666667 162 1.11E-11 -1.088687216 GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0071300///cellular response to retinoic acid 226470 226470 'Zbtb41' mRNA 319 294 257 2.32 1.99 1.69 1.74 1.93 2.13 2 1.933333333 322 348 321 290 330.3333333 0.290848898 0.179489323 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 22648 22648 'Zfp11' mRNA 206.61 229.16 237.62 2.85 3.11 3.48 2.04 1.72 2.28 3.146666667 2.013333333 170.5 140.14 184.18 224.4633333 164.94 0.022169383 -0.458968089 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 226499 226499 'Odr4' mRNA 970.33 969.33 969.15 16.38 16.14 17.38 13.03 13.33 14.58 16.63333333 13.64666667 883.8 884.76 958.35 969.6033333 908.97 0.338769091 -0.105939778 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008104///protein localization 226517 226517 'Smg7' mRNA 1863 1735 1399 16.81 15.35 13.3 9.81 7.7 8.56 15.15333333 8.69 1248 961 1065 1665.666667 1091.333333 1.85E-09 -0.619234645 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton GO:0042162///telomeric DNA binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070034///telomerase RNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 226518 226518 'Nmnat2' mRNA 566 538 457 6.74 6.4 5.88 5.57 5.78 5.4 6.34 5.583333333 528 544 507 520.3333333 526.3333333 0.961780758 0.00815985 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0000309///nicotinamide-nucleotide adenylyltransferase activity+++GO:0003824///catalytic activity+++GO:0004515///nicotinate-nucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0009058///biosynthetic process+++GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process 226519 226519 'Lamc1' mRNA 1849 1870 1660 12.78 12.7 12.17 14.25 13.95 14.94 12.55 14.38 2375 2272 2411 1793 2352.666667 2.04E-08 0.381813619 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05020///Prion disease+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005606///laminin-1 complex+++GO:0005608///laminin-3 complex+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0043083///synaptic cleft+++GO:0043256///laminin complex+++GO:0043259///laminin-10 complex+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0043208///glycosphingolipid binding GO:0000904///cell morphogenesis involved in differentiation+++GO:0007155///cell adhesion+++GO:0007411///axon guidance+++GO:0007528///neuromuscular junction development+++GO:0007601///visual perception+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0014002///astrocyte development+++GO:0014044///Schwann cell development+++GO:0016477///cell migration+++GO:0022617///extracellular matrix disassembly+++GO:0031175///neuron projection development+++GO:0031581///hemidesmosome assembly+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0048677///axon extension involved in regeneration+++GO:0050808///synapse organization+++GO:0060041///retina development in camera-type eye+++GO:0065003///protein-containing complex assembly+++GO:0070831///basement membrane assembly+++GO:0072249///metanephric glomerular visceral epithelial cell development+++GO:0072274///metanephric glomerular basement membrane development 22652 22652 'Mkrn3' mRNA 95 58 78 2.06 1.24 1.8 0.72 0.66 0.96 1.7 0.78 38 34 49 77 40.33333333 0.008609056 -0.947281881 GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 226525 226525 'Rasal2' mRNA 3117.4 3081.73 2753.25 16.6 16.25 15.46 7.44 7.23 7.65 16.10333333 7.44 1658.63 1537.03 1615.13 2984.126667 1603.596667 2.49E-44 -0.906355437 04014///Ras signaling pathway GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity 226527 226527 'Cryzl2' mRNA 1086.4 1200.15 1043.28 38.51 41.31 38.46 28.76 31.32 29.82 39.42666667 29.96666667 937.35 990.02 895.95 1109.943333 941.1066667 0.009822173 -0.248075731 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity 226539 226539 'Dars2' mRNA 289 292 287 4.34 4.31 4.56 4.61 5.38 4.37 4.403333333 4.786666667 354 403 325 289.3333333 360.6666667 0.055959631 0.306801832 00970///Aminoacyl-tRNA biosynthesis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004815///aspartate-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042803///protein homodimerization activity+++GO:0050560///aspartate-tRNA(Asn) ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006422///aspartyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0070145///mitochondrial asparaginyl-tRNA aminoacylation 22654 22654 'Zfp13' mRNA 332 309 301 7.37 6.51 7.33 4.15 5.06 4.8 7.07 4.67 210 252 222 314 228 0.004173275 -0.47159194 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005739///mitochondrion "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010729///positive regulation of hydrogen peroxide biosynthetic process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway" 226541 226541 'Klhl20' mRNA 362 314 294 4.84 4.13 4.16 4.37 3.89 3.67 4.376666667 3.976666667 377 328 306 323.3333333 337 0.81785723 0.04848346 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0019964///interferon-gamma binding GO:0006895///Golgi to endosome transport+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1990390///protein K33-linked ubiquitination 226548 226548 'Aph1a' mRNA 1406.38 1386.59 1022.78 24.8 24.21 19.27 25.88 20.43 23.4 22.76 23.23666667 1686.27 1303.59 1472.37 1271.916667 1487.41 0.062069716 0.218314818 04330///Notch signaling pathway+++05010///Alzheimer disease GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0070765///gamma-secretase complex+++GO:0097060///synaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0019899///enzyme binding+++GO:0030674///protein binding, bridging+++GO:0061133///endopeptidase activator activity" GO:0001656///metanephros development+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0042982///amyloid precursor protein metabolic process+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043085///positive regulation of catalytic activity 226551 226551 'Suco' mRNA 1047 1049 895 9.43 9.25 8.48 8.38 7.11 7.88 9.053333333 7.79 1073 889 967 997 976.3333333 0.750936661 -0.040731291 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030867///rough endoplasmic reticulum membrane GO:0003674///molecular_function GO:0001503///ossification+++GO:0007275///multicellular organism development+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046850///regulation of bone remodeling 226562 226562 'Prrc2c' mRNA 3044 2902.11 3074 18.91 18.27 19.21 17.34 16.06 17.08 18.79666667 16.82666667 3286 3023 3130 3006.703333 3146.333333 0.571240782 0.051239724 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule GO:0008022///protein C-terminus binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0030154///cell differentiation+++GO:0034063///stress granule assembly 226564 226564 'Fmo4' mRNA 1 1 2 0.03 0.02 0.06 0 0.03 0 0.036666667 0.01 0 1 0 1.333333333 0.333333333 0.5678623 -1.924954074 00982///Drug metabolism - cytochrome P450 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0042178///xenobiotic catabolic process+++GO:0042737///drug catabolic process 22658 22658 'Pcgf2' mRNA 254 216 146 4.37 3.55 2.1 2.32 2.15 2.66 3.34 2.376666667 148 133 159 205.3333333 146.6666667 0.033067672 -0.48906269 04550///Signaling pathways regulating pluripotency of stem cells GO:0000785///chromatin+++GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006342///chromatin silencing+++GO:0009952///anterior/posterior pattern specification+++GO:0016573///histone acetylation+++GO:0031507///heterochromatin assembly+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048706///embryonic skeletal system development+++GO:0050790///regulation of catalytic activity+++GO:0070301///cellular response to hydrogen peroxide+++GO:2001234///negative regulation of apoptotic signaling pathway 226591 226591 'Tiprl' mRNA 1152 1213 1085 32.35 33.9 32.69 32.48 37.47 34.86 32.98 34.93666667 1333 1485 1351 1150 1389.666667 0.003595655 0.263695736 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0000077///DNA damage checkpoint+++GO:0031929///TOR signaling+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0043666///regulation of phosphoprotein phosphatase activity 226594 226594 'Rcsd1' mRNA 335 380 356 7.02 7.87 7.93 13.38 14.23 14.59 7.606666667 14.06666667 736 771 784 357 763.6666667 1.97E-21 1.085823291 GO:0005575///cellular_component GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0071474///cellular hyperosmotic response 22661 22661 'Zfp148' mRNA 1437.24 1385.14 1229.54 11.76 10.44 10.53 9.14 8.33 8.83 10.91 8.766666667 1307.26 1089.89 1194.24 1350.64 1197.13 0.047450222 -0.185258772 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007276///gamete generation+++GO:0010629///negative regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0065003///protein-containing complex assembly" 226610 226610 'Fam78b' mRNA 42 36 33 0.36 0.32 0.29 0.29 0.18 0.23 0.323333333 0.233333333 36 22 27 37 28.33333333 0.441214855 -0.398109645 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 226641 226641 'Atf6' mRNA 1167 1196 1033 8.15 8.19 7.67 6.95 5.99 6.92 8.003333333 6.62 1137 962 1099 1132 1066 0.360152398 -0.097272045 04141///Protein processing in endoplasmic reticulum+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05417///Lipid and atherosclerosis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0007601///visual perception+++GO:0010508///positive regulation of autophagy+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903893///positive regulation of ATF6-mediated unfolded protein response+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 226646 226646 'Ndufs2' mRNA 3735 3649 3650 134.41 129.43 139.19 135.21 137.78 135.99 134.3433333 136.3266667 4324 4299 4209 3678 4277.333333 0.001224322 0.205406144 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain "GO:0003954///NADH dehydrogenase activity+++GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0019826///oxygen sensor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0048038///quinone binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0006979///response to oxidative stress+++GO:0022008///neurogenesis+++GO:0022900///electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0042063///gliogenesis+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0061351///neural precursor cell proliferation+++GO:0071453///cellular response to oxygen levels" 226652 226652 'Arhgap30' mRNA 97 75 91 1.16 0.88 1.15 12.97 11.65 12.26 1.063333333 12.29333333 1248 1095 1143 87.66666667 1162 3.62E-164 3.714951684 GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 226654 226654 'Tstd1' mRNA 270 202 196 39.17 29.24 30.19 8.79 8.66 8.2 32.86666667 8.55 69 66 62 222.6666667 65.66666667 2.25E-15 -1.77136067 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003674///molecular_function+++GO:0050337///thiosulfate-thiol sulfurtransferase activity "GO:0008150///biological_process+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase" 22666 22666 'Zbtb14' mRNA 716 747 610 10.44 10.71 9.5 7.81 6.58 7 10.21666667 7.13 615 516 532 691 554.3333333 0.004776554 -0.327784083 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016235///aggresome "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0003170///heart valve development+++GO:0003279///cardiac septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060976///coronary vasculature development" 22668 22668 'Sf1' mRNA 3313 3388 2707 58.14 58.61 52.48 48.51 46.77 49.74 56.41 48.34 3105 2878 3019 3136 3000.666667 0.397294816 -0.071679194 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0045131///pre-mRNA branch point binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0030238///male sex determination+++GO:0030575///nuclear body organization+++GO:0033327///Leydig cell differentiation+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050810///regulation of steroid biosynthetic process" 226691 226691 'Ifi207' mRNA 118.04 132.76 89 1.82 2.02 1.45 21.15 19.91 21.68 1.763333333 20.91333333 1580.84 1452.76 1569.51 113.2666667 1534.37 2.37E-210 3.754146745 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002218///activation of innate immune response+++GO:0030224///monocyte differentiation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0040029///regulation of gene expression, epigenetic+++GO:0042149///cellular response to glucose starvation+++GO:0043392///negative regulation of DNA binding+++GO:0045071///negative regulation of viral genome replication+++GO:0045824///negative regulation of innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0071479///cellular response to ionizing radiation+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:2000117///negative regulation of cysteine-type endopeptidase activity" 226695 226695 'Ifi205' mRNA 3.28 7.5 2.85 0.12 0.22 0.11 10.16 10.43 10.49 0.15 10.36 341.45 343.23 341.97 4.543333333 342.2166667 8.57E-45 6.407638341 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009617///response to bacterium+++GO:0030889///negative regulation of B cell proliferation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway 22670 22670 'Trim26' mRNA 1535 1676 1500 26.24 28.2 27.16 27.99 28.13 29.52 27.2 28.54666667 1884 1851 1925 1570.333333 1886.666667 7.90E-04 0.254116555 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0002376///immune system process+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1902187///negative regulation of viral release from host cell 22671 22671 'Rnf112' mRNA 12 10 4 0.22 0.18 0.08 0.27 0.08 0.29 0.16 0.213333333 17 5 18 8.666666667 13.33333333 0.533249015 0.618501938 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0019898///extrinsic component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0044297///cell body+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016740///transferase activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007029///endoplasmic reticulum organization+++GO:0007050///cell cycle arrest+++GO:0007399///nervous system development+++GO:0016567///protein ubiquitination+++GO:0030182///neuron differentiation+++GO:0033194///response to hydroperoxide+++GO:0036473///cell death in response to oxidative stress+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0045666///positive regulation of neuron differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0051260///protein homooligomerization+++GO:0051726///regulation of cell cycle+++GO:0051865///protein autoubiquitination+++GO:0070315///G1 to G0 transition involved in cell differentiation+++GO:0071158///positive regulation of cell cycle arrest+++GO:1990403///embryonic brain development 22673 22673 'Zfp185' mRNA 1733 1740 1772 26.49 26.2 28.75 13.06 15.12 14.19 27.14666667 14.12333333 985 1112 1034 1748.333333 1043.666667 1.00E-17 -0.756303872 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction GO:0046872///metal ion binding+++GO:0051015///actin filament binding 226744 226744 'Cnst' mRNA 1253 1238 1093 14.67 14.32 13.62 8.41 6.59 6.87 14.20333333 7.29 823 632 652 1194.666667 702.3333333 5.04E-14 -0.778325279 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0071253///connexin binding GO:0010923///negative regulation of phosphatase activity+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport 226747 226747 'Ahctf1' mRNA 778 782 450 4.62 4.57 2.84 2.92 2.95 2.94 4.01 2.936666667 566 558 552 670 558.6666667 0.125051027 -0.262630194 03013///Nucleocytoplasmic transport "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0031080///nuclear pore outer ring+++GO:0031965///nuclear membrane" GO:0003677///DNA binding GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0015031///protein transport+++GO:0030097///hemopoiesis+++GO:0032465///regulation of cytokinesis+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0051301///cell division 226751 226751 'Cdc42bpa' mRNA 1702.64 1667.22 1621.59 9.46 9.02 9.52 4.98 3.95 4.44 9.333333333 4.456666667 1037.88 792.87 895.18 1663.816667 908.6433333 1.29E-21 -0.887286424 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0042641///actomyosin+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0007097///nuclear migration+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction 226757 226757 'Wdr26' mRNA 1291 1298 1174 11.2 11.22 10.83 16.28 14.79 15.82 11.08333333 15.63 2159 1876 2015 1254.333333 2016.666667 2.09E-19 0.673638573 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0034657///GID complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 226777 226777 'C130074G19Rik' mRNA 205 196 195 3.96 3.73 4 4.03 4.73 3.97 3.896666667 4.243333333 240 275 229 198.6666667 248 0.099998054 0.30914907 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097731///9+0 non-motile cilium GO:0003674///molecular_function GO:0008150///biological_process 226778 226778 'Mark1' mRNA 172 186 128 2.18 2.4 1.95 0.97 1.15 1.38 2.176666667 1.166666667 84 99 113 162 98.66666667 0.00280567 -0.718923198 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001786///phosphatidylserine binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0050321///tau-protein kinase activity+++GO:0070300///phosphatidic acid binding" GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0010975///regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0050773///regulation of dendrite development+++GO:0051654///establishment of mitochondrion localization 22678 22678 'Zfp2' mRNA 688.43 683 633 10.88 10.66 10.45 4.23 3.47 3.89 10.66333333 3.863333333 302 259 270 668.1433333 277 2.92E-27 -1.281768623 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 226781 226781 'Slc30a10' mRNA 231 210 195 2.1 1.88 1.88 2.36 1.93 1.76 1.953333333 2.016666667 298 238 216 212 250.6666667 0.256697442 0.229332462 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0005385///zinc ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006828///manganese ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0010312///detoxification of zinc ion+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0055085///transmembrane transport+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071421///manganese ion transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0071579///regulation of zinc ion transport+++GO:0098655///cation transmembrane transport+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1904385///cellular response to angiotensin+++GO:1905802///regulation of cellular response to manganese ion+++GO:2000773///negative regulation of cellular senescence 226791 226791 'Lyplal1' mRNA 375 305 362 13.95 11.19 14.28 14.8 15.46 15.16 13.14 15.14 457 466 453 347.3333333 458.6666667 0.007999176 0.387080123 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0002084///protein depalmitoylation+++GO:0042997///negative regulation of Golgi to plasma membrane protein transport 22680 22680 'Zfp207' mRNA 3466 3433 3348 90.64 89.06 92.73 93.92 88.32 90.52 90.81 90.92 4041 3719 3769 3415.666667 3843 0.014014694 0.157462072 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:1990047///spindle matrix" GO:0008017///microtubule binding+++GO:0008201///heparin binding+++GO:0046872///metal ion binding GO:0000070///mitotic sister chromatid segregation+++GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0046785///microtubule polymerization+++GO:0050821///protein stabilization+++GO:0051301///cell division+++GO:0051983///regulation of chromosome segregation+++GO:0090307///mitotic spindle assembly 22682 22682 'Zfand5' mRNA 3884.73 4001.13 1007.31 74.76 75.89 19.66 20.84 43.72 39.83 56.77 34.79666667 1257.71 2538.7 2320.16 2964.39 2038.856667 0.524976764 -0.518469575 GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0001944///vasculature development+++GO:0003016///respiratory system process+++GO:0010761///fibroblast migration+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0060324///face development 226823 226823 'Kctd3' mRNA 739 829 330 11.39 12.79 5.77 4.08 3.98 4.25 9.983333333 4.103333333 283 271 293 632.6666667 282.3333333 0.002821821 -1.157077639 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding GO:0008150///biological_process+++GO:0051260///protein homooligomerization 226830 226830 'Smyd2' mRNA 1130 1174 995 41.11 42.47 38.42 35.7 36.13 35.52 40.66666667 35.78333333 1125 1108 1089 1099.666667 1107.333333 0.998591786 7.82E-04 00310///Lysine degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000993///RNA polymerase II complex binding+++GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0010452///histone H3-K36 methylation+++GO:0016571///histone methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator" 226841 226841 'Vash2' mRNA 222 265 226 3 3.55 3.26 0.6 0.65 0.74 3.27 0.663333333 52 54 62 237.6666667 56 4.80E-22 -2.095298616 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0000768///syncytium formation by plasma membrane fusion+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006508///proteolysis+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0060674///placenta blood vessel development+++GO:0060711///labyrinthine layer development+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061564///axon development+++GO:0140253///cell-cell fusion 226844 226844 'Flvcr1' mRNA 179 182 153 2.44 2.5 2.23 2.75 2.05 2.21 2.39 2.336666667 232 165 174 171.3333333 190.3333333 0.575274776 0.139794431 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0022857///transmembrane transporter activity GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0006839///mitochondrial transport+++GO:0015886///heme transport+++GO:0030218///erythrocyte differentiation+++GO:0035108///limb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0042733///embryonic digit morphogenesis+++GO:0043249///erythrocyte maturation+++GO:0046620///regulation of organ growth+++GO:0048536///spleen development+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0055085///transmembrane transport+++GO:0060323///head morphogenesis+++GO:0097037///heme export 226849 226849 'Ppp2r5a' mRNA 335.98 355 303 5.98 6.21 5.72 9.52 9.48 9.85 5.97 9.616666667 616 599.02 617.02 331.3266667 610.68 8.00E-14 0.873852923 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection "GO:0000159///protein phosphatase type 2A complex+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0031430///M band" GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0019900///kinase binding+++GO:0072542///protein phosphatase activator activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0031952///regulation of protein autophosphorylation+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0090219///negative regulation of lipid kinase activity+++GO:1903077///negative regulation of protein localization to plasma membrane 22685 22685 'Zfp239' mRNA 246 260 247 3.79 3.97 4.06 1.62 1.77 1.92 3.94 1.77 123 127 133 251 127.6666667 4.63E-08 -0.98666672 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 226856 226856 'Lpgat1' mRNA 2173 2180 1899 17.21 16.76 15.91 7.59 6.44 6.97 16.62666667 7 1111 929 1005 2084 1015 6.14E-40 -1.048637898 00564///Glycerophospholipid metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0071617///lysophospholipid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0045723///positive regulation of fatty acid biosynthetic process 226861 226861 'Hhat' mRNA 84 126 97 1.67 2.41 2 2.52 2.61 2.88 2.026666667 2.67 149 151 164 102.3333333 154.6666667 0.015358822 0.586680076 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0018009///N-terminal peptidyl-L-cysteine N-palmitoylation+++GO:0018345///protein palmitoylation 226866 226866 'Sbspon' mRNA 1701 1533 1484 34.22 30.36 31.67 18.17 19.05 19.25 32.08333333 18.82333333 1039 1064 1066 1572.666667 1056.333333 2.49E-12 -0.584717839 GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 22687 22687 'Zpr1' mRNA 942 955 958 17.35 17.31 18.71 17.22 17.49 16.5 17.79 17.07 1076 1067 998 951.6666667 1047 0.228778209 0.125014479 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0097504///Gemini of coiled bodies GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031369///translation initiation factor binding+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0001833///inner cell mass cell proliferation+++GO:0001834///trophectodermal cell proliferation+++GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0021510///spinal cord development+++GO:0030154///cell differentiation+++GO:0030576///Cajal body organization+++GO:0031641///regulation of myelination+++GO:0033120///positive regulation of RNA splicing+++GO:0042023///DNA endoreduplication+++GO:0042307///positive regulation of protein import into nucleus+++GO:0045927///positive regulation of growth+++GO:0061564///axon development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071931///positive regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:1902742///apoptotic process involved in development+++GO:1990261///pre-mRNA catabolic process+++GO:2000672///negative regulation of motor neuron apoptotic process 22688 22688 'Zfp26' mRNA 731 777 603 5.58 5.77 4.79 3.97 3.13 3.98 5.38 3.693333333 608 480 594 703.6666667 560.6666667 0.007548789 -0.336716433 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 22689 22689 'Zfp27' mRNA 348 372 321 5.19 5.5 5.14 3.88 3.97 2.99 5.276666667 3.613333333 295 298 219 347 270.6666667 0.029562435 -0.368539018 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 226896 226896 'Tfap2d' mRNA 593.04 600.99 487.29 3.33 3.32 2.91 2 1.55 1.98 3.186666667 1.843333333 410.66 310.32 394.62 560.44 371.8666667 8.68E-06 -0.60256478 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development+++GO:0061379///inferior colliculus development" 22690 22690 'Zfp28' mRNA 332 342 355 4.31 4.37 4.89 2.59 2.13 1.88 4.523333333 2.2 229 184 161 343 191.3333333 4.76E-07 -0.857888136 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22691 22691 'Zscan2' mRNA 220.88 184.75 184.06 0.85 0.68 0.67 1 1.06 1 0.733333333 1.02 315.06 322.4 321.71 196.5633333 319.7233333 1.71E-05 0.693608314 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 226922 226922 'Kcnq5' mRNA 5.43 7.84 1 0.02 0.03 0 0.01 0.01 0.01 0.016666667 0.01 1 2.76 2 4.756666667 1.92 0.436284536 -1.359850453 04725///Cholinergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030118///clathrin coat GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 22693 22693 'Zfp30' mRNA 355 382 328 5.37 5.64 5.29 3.65 3.5 3.56 5.433333333 3.57 275 260 262 355 265.6666667 0.003411827 -0.428317398 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22694 22694 'Zfp35' mRNA 654 641 654 14.77 14.18 15.81 12.57 11.33 11.95 14.92 11.95 641 572 587 649.6666667 600 0.306653202 -0.128308264 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0002437///inflammatory response to antigenic stimulus+++GO:0002829///negative regulation of type 2 immune response+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 22695 22695 'Zfp36' mRNA 945 988 928 30.93 31.88 32.23 60.33 66.07 59.31 31.68 61.90333333 2118 2264 2015 953.6666667 2132.333333 8.39E-46 1.150074833 05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0000178///exosome (RNase complex)+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030014///CCR4-NOT complex+++GO:0070578///RISC-loading complex+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019957///C-C chemokine binding+++GO:0031072///heat shock protein binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0070063///RNA polymerase binding+++GO:0071889///14-3-3 protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006402///mRNA catabolic process+++GO:0007275///multicellular organism development+++GO:0009611///response to wounding+++GO:0010837///regulation of keratinocyte proliferation+++GO:0031086///nuclear-transcribed mRNA catabolic process, deadenylation-independent decay+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032897///negative regulation of viral transcription+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035556///intracellular signal transduction+++GO:0038066///p38MAPK cascade+++GO:0042594///response to starvation+++GO:0043488///regulation of mRNA stability+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045616///regulation of keratinocyte differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0050779///RNA destabilization+++GO:0051028///mRNA transport+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901835///positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA+++GO:1902172///regulation of keratinocyte apoptotic process+++GO:1904246///negative regulation of polynucleotide adenylyltransferase activity+++GO:1904582///positive regulation of intracellular mRNA localization+++GO:2000637///positive regulation of gene silencing by miRNA" 22696 22696 'Zfp37' mRNA 378.99 348.02 388.01 5.74 5.11 6.26 3.82 3.59 4.12 5.703333333 3.843333333 298 272.78 302.95 371.6733333 291.2433333 0.01604337 -0.367960297 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation" 22697 22697 'Zscan21' mRNA 911 948 814 22.43 23 21.21 19.19 17.52 16.78 22.21333333 17.83 893 804 762 891 819.6666667 0.235726387 -0.130832821 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007141///male meiosis I+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle" 226970 226970 'Arhgef4' mRNA 162 195 177 2.91 2.84 2.73 1.45 2.16 1.93 2.826666667 1.846666667 116 146 151 178 137.6666667 0.095425075 -0.380344579 04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019904///protein domain specific binding GO:0030032///lamellipodium assembly+++GO:0035556///intracellular signal transduction+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 226971 226971 'Plekhb2' mRNA 3391.85 3344 3427 55.71 54.05 59.72 54.63 52.41 53.19 56.49333333 53.41 3826.18 3579.8 3608.64 3387.616667 3671.54 0.163950335 0.102378065 GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055038///recycling endosome membrane "GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding" GO:0045595///regulation of cell differentiation 226976 226976 'Kansl3' mRNA 1779 1951 1883 20.16 21.77 22.65 19.52 17.69 19.09 21.52666667 18.76666667 1978 1750 1871.85 1871 1866.616667 0.866831518 -0.017059336 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044545///NSL complex GO:0006325///chromatin organization+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II 226977 226977 'Actr1b' mRNA 2155 2229 2182 46.68 48.26 50.64 52.56 55.02 53.35 48.52666667 53.64333333 2746 2784 2713 2188.666667 2747.666667 5.24E-06 0.316045155 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0000166///nucleotide binding+++GO:0005524///ATP binding 22698 22698 'Zfp39' mRNA 463.4 379 419 6.44 5.18 6.18 3.19 3.68 3.89 5.933333333 3.586666667 264 298 312 420.4666667 291.3333333 4.13E-04 -0.540615934 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation" 226982 226982 'Eif5b' mRNA 1439.05 1354.55 1387.19 12.45 11.53 12.57 14.33 14.11 13.97 12.18333333 14.13666667 1864.89 1797.42 1766.51 1393.596667 1809.606667 3.39E-06 0.363882843 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation 226999 226999 'Slc9a2' mRNA 278 316 304 4.33 4.84 5.02 3.21 3.23 3.4 4.73 3.28 237 233 243 299.3333333 237.6666667 0.036830757 -0.345310867 GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0008104///protein localization+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 22700 22700 'Zfp40' mRNA 418 440 414 3.39 3.69 3.63 2.56 3.08 2.78 3.57 2.806666667 337 389 332 424 352.6666667 0.059149426 -0.276168852 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 22701 22701 'Zfp41' mRNA 219 223 179 3.04 3.19 2.66 1.81 1.89 2.48 2.963333333 2.06 156 149 200 207 168.3333333 0.156642936 -0.305930143 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 22702 22702 'Zfp42' mRNA 0 1 1 0 0.03 0.03 0.06 0.03 0.03 0.02 0.04 2 1 1 0.666666667 1.333333333 0.761668857 0.972143207 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0031519///PcG protein complex+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001701///in utero embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007286///spermatid development+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000653///regulation of genetic imprinting 22704 22704 'Zfp46' mRNA 324 332 376 3.7 3.64 4.48 3.61 3.96 3 3.94 3.523333333 367 400 294 344 353.6666667 0.907423123 0.024789748 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227058 227058 'Dnah7b' mRNA 175.94 179.11 195.23 0.97 1.03 1.1 0.62 0.38 0.43 1.033333333 0.476666667 127.29 72.56 82.96 183.4266667 94.27 6.01E-05 -0.985708115 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0036159///inner dynein arm assembly 227059 227059 'Slc39a10' mRNA 1239 1264 1177 11.82 11.8 11.72 10.35 10.04 9.4 11.78 9.93 1223 1143 1083 1226.666667 1149.666667 0.274264819 -0.105216592 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0002903///negative regulation of B cell apoptotic process+++GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0030890///positive regulation of B cell proliferation+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0055085///transmembrane transport+++GO:0071578///zinc ion import across plasma membrane+++GO:1903615///positive regulation of protein tyrosine phosphatase activity 22709 22709 'Zfp51' mRNA 326 333 375 7.02 7.03 8.5 5.77 5.59 6.06 7.516666667 5.806666667 308 292 313.9 344.6666667 304.6333333 0.253735323 -0.19501231 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 227094 227094 'Nemp2' mRNA 210 183 226 3.37 2.89 3.85 3.07 2.68 2.1 3.37 2.616666667 220 188 146 206.3333333 184.6666667 0.477691415 -0.178066466 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 227095 227095 'Hibch' mRNA 331 333 366 10.35 10.26 12.14 9.52 9.26 10.32 10.91666667 9.7 350 332 367 343.3333333 349.6666667 0.953808861 0.011730533 "00280///Valine, leucine and isoleucine degradation+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005739///mitochondrion GO:0003860///3-hydroxyisobutyryl-CoA hydrolase activity+++GO:0016787///hydrolase activity GO:0006574///valine catabolic process+++GO:0009083///branched-chain amino acid catabolic process 227099 227099 'Pms1' mRNA 138 173 129 2.22 2.67 2.24 1.59 1.96 1.91 2.376666667 1.82 116 137 132 146.6666667 128.3333333 0.451091164 -0.199078472 GO:0005634///nucleus+++GO:0032300///mismatch repair complex GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding+++GO:0030983///mismatched DNA binding GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0042493///response to drug 22710 22710 'Zfp52' mRNA 66 94 97 1.12 1.58 1.74 3.48 3.48 3.63 1.48 3.53 237 231 237 85.66666667 235 1.62E-11 1.440915785 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 227102 227102 'Ormdl1' mRNA 725 733 714 22.57 22.48 23.58 22.07 21.22 20.54 22.87666667 21.27666667 815 765 734 724 771.3333333 0.5220282 0.078886966 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035339///SPOTS complex GO:0003674///molecular_function GO:0006672///ceramide metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0042552///myelination+++GO:0061744///motor behavior+++GO:0090153///regulation of sphingolipid biosynthetic process+++GO:0090155///negative regulation of sphingolipid biosynthetic process+++GO:0090156///cellular sphingolipid homeostasis+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:2000303///regulation of ceramide biosynthetic process 22712 22712 'Zfp54' mRNA 147 123 133 3.6 3.1 3.56 2.81 2.76 3.51 3.42 3.026666667 126 122 159 134.3333333 135.6666667 0.998591786 0.002083612 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227120 227120 'Plcl1' mRNA 98 100 55 0.79 0.79 0.47 0.38 0.33 0.36 0.683333333 0.356666667 54 46 50 84.33333333 50 0.026237769 -0.756067422 04727///GABAergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane "GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0050811///GABA receptor binding+++GO:0070679///inositol 1,4,5 trisphosphate binding" "GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1900122///positive regulation of receptor binding" 22715 22715 'Zfp57' mRNA 52.69 71.31 44.83 0.47 0.94 0.87 2.1 1.74 1.62 0.76 1.82 102.26 94.16 78.14 56.27666667 91.52 0.025274589 0.708032761 05168///Herpes simplex virus 1 infection GO:0000792///heterochromatin+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0010216///maintenance of DNA methylation+++GO:0043045///DNA methylation involved in embryo development+++GO:0071514///genetic imprinting+++GO:0071517///maintenance of imprinting at mating-type locus+++GO:2000653///regulation of genetic imprinting" 227154 227154 'Stradb' mRNA 498 479 386 11.78 11.16 9.68 11.66 12.64 12.49 10.87333333 12.26333333 567 600 588 454.3333333 585 0.004414395 0.357588984 04150///mTOR signaling pathway+++04152///AMPK signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding GO:0000902///cell morphogenesis+++GO:0006468///protein phosphorylation+++GO:0006611///protein export from nucleus+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007254///JNK cascade+++GO:0032147///activation of protein kinase activity+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 227157 227157 'Mpp4' mRNA 26 35.33 38.36 0.62 0.68 0.79 0.27 0.29 0.55 0.696666667 0.37 16.56 17.4 33.52 33.23 22.49333333 0.297068094 -0.599752389 04530///Tight junction GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0016328///lateral plasma membrane+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0044316///cone cell pedicle+++GO:0044317///rod spherule+++GO:0045178///basal part of cell GO:0005102///signaling receptor binding GO:0035418///protein localization to synapse 22717 22717 'Zfp59' mRNA 261.56 196.45 150.33 3.73 2.67 2.22 1.69 1.77 2.03 2.873333333 1.83 137 143.11 162 202.78 147.37 0.048995161 -0.461516146 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22718 22718 'Zfp60' mRNA 1040.44 1119.55 1058.53 14.36 15.21 15.43 11.92 10.19 9.75 15 10.62 988.86 822 781 1072.84 863.9533333 0.001929573 -0.325887467 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 22719 22719 'Zfp61' mRNA 473 568 505 11.08 13.16 12.64 5.98 7.25 5.57 12.29333333 6.266666667 291 343 263 515.3333333 299 4.61E-08 -0.79551753 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227195 227195 'Ino80d' mRNA 967 956 823 7.08 5.91 5.6 5.66 5.03 4.85 6.196666667 5.18 893 776 785 915.3333333 818 0.102178244 -0.172500991 GO:0005634///nucleus GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008150///biological_process 227197 227197 'Ndufs1' mRNA 2381 2575 2715 48.63 51.13 58.75 45.23 45.89 44.84 52.83666667 45.32 2558 2535 2456 2557 2516.333333 0.739263611 -0.037877178 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain "GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0008637///apoptotic mitochondrial changes+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0042773///ATP synthesis coupled electron transport+++GO:0045333///cellular respiration+++GO:0046034///ATP metabolic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0072593///reactive oxygen species metabolic process" 22720 22720 'Zfp62' mRNA 1106.24 1132 1052 13.56 13.65 13.34 9.29 8.46 10.09 13.51666667 9.28 891 801.17 926 1096.746667 872.7233333 2.52E-04 -0.341205594 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 227210 227210 'Ccnyl1' mRNA 87 66 69 1.65 1.23 1.38 2.66 2.06 2.37 1.42 2.363333333 163 121 139 74 141 3.10E-04 0.91672122 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001932///regulation of protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0030317///flagellated sperm motility+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045859///regulation of protein kinase activity+++GO:0060828///regulation of canonical Wnt signaling pathway 22722 22722 'Zfp64' mRNA 513 566 508 10.26 11.16 10.8 9.05 7.92 8.36 10.74 8.443333333 520 444 465 529 476.3333333 0.223221752 -0.163358983 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 227231 227231 'Cps1' mRNA 30 16 22 0.29 0.15 0.23 0.03 0.03 0.04 0.223333333 0.033333333 4 4 5 22.66666667 4.333333333 0.001484736 -2.400109346 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00910///Nitrogen metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids" GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0032991///protein-containing complex+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004087///carbamoyl-phosphate synthase (ammonia) activity+++GO:0004088///carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity+++GO:0004175///endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005543///phospholipid binding+++GO:0016595///glutamate binding+++GO:0016874///ligase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0072341///modified amino acid binding GO:0000050///urea cycle+++GO:0001889///liver development+++GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006508///proteolysis+++GO:0006541///glutamine metabolic process+++GO:0006807///nitrogen compound metabolic process+++GO:0007494///midgut development+++GO:0008152///metabolic process+++GO:0009636///response to toxic substance+++GO:0010043///response to zinc ion+++GO:0014075///response to amine+++GO:0019433///triglyceride catabolic process+++GO:0032094///response to food+++GO:0032496///response to lipopolysaccharide+++GO:0033762///response to glucagon+++GO:0034201///response to oleic acid+++GO:0042311///vasodilation+++GO:0042493///response to drug+++GO:0042594///response to starvation+++GO:0043200///response to amino acid+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0046209///nitric oxide metabolic process+++GO:0048545///response to steroid hormone+++GO:0050667///homocysteine metabolic process+++GO:0051384///response to glucocorticoid+++GO:0051591///response to cAMP+++GO:0055081///anion homeostasis+++GO:0060416///response to growth hormone+++GO:0070365///hepatocyte differentiation+++GO:0070409///carbamoyl phosphate biosynthetic process+++GO:0071242///cellular response to ammonium ion+++GO:0071320///cellular response to cAMP+++GO:0071377///cellular response to glucagon stimulus+++GO:0071400///cellular response to oleic acid+++GO:0071548///response to dexamethasone 22724 22724 'Zbtb7b' mRNA 577 606 380 8.45 8.64 5.88 8.46 7.87 7.52 7.656666667 7.95 663 604 572 521 613 0.144165389 0.230799663 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001865///NK T cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007595///lactation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031065///positive regulation of histone deacetylation+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032868///response to insulin+++GO:0043370///regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0043376///regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0043377///negative regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0051141///negative regulation of NK T cell proliferation+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1990845///adaptive thermogenesis+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000640///positive regulation of SREBP signaling pathway" 227288 227288 'Cxcr1' mRNA 0 4 0 0 0.27 0 0.68 1.14 1.05 0.09 0.956666667 14 23 20 1.333333333 19 5.06E-04 3.842931807 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004918///interleukin-8 receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0019959///interleukin-8 binding GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0030593///neutrophil chemotaxis+++GO:0031623///receptor internalization+++GO:0038112///interleukin-8-mediated signaling pathway+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 227289 227289 'Gpbar1' mRNA 3 2 0 0.19 0.13 0 0.06 0 0.12 0.106666667 0.06 1 0 2 1.666666667 1 0.81918928 -0.722702714 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0038181///bile acid receptor activity+++GO:0038182///G protein-coupled bile acid receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0038184///cell surface bile acid receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1903413///cellular response to bile acid+++GO:1904056///positive regulation of cholangiocyte proliferation+++GO:2000810///regulation of bicellular tight junction assembly 227290 227290 'Aamp' mRNA 5811 6062 6066 183.95 189.12 203.75 185.37 198.32 181.96 192.2733333 188.55 6730 7027 6395 5979.666667 6717.333333 0.029294955 0.155085329 GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge GO:0008201///heparin binding GO:0014909///smooth muscle cell migration 227292 227292 'Ctdsp1' mRNA 1685 1800 1482.95 32.82 34.49 30.75 36.18 39 38.66 32.68666667 37.94666667 2115.71 2225.91 2189.5 1655.983333 2177.04 4.28E-07 0.386423739 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006470///protein dephosphorylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0050768///negative regulation of neurogenesis+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 227298 227298 'Retreg2' mRNA 1657 1871 871 38.08 42.49 22.05 19.9 21.01 20.79 34.20666667 20.56666667 962 995 974 1466.333333 977 0.07744513 -0.581044192 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 227325 227325 'Dner' mRNA 2566.91 2816 2838.93 38.35 41.39 44.99 3.35 3.08 3.14 41.57666667 3.19 258 231.91 234 2740.613333 241.3033333 3.95E-282 -3.521521425 GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005112///Notch binding+++GO:0005509///calcium ion binding GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0010001///glial cell differentiation+++GO:0030154///cell differentiation+++GO:0048741///skeletal muscle fiber development 227326 227326 'Gpr55' mRNA 3 7 0 0.04 0.1 0 0.07 0.04 0.06 0.046666667 0.056666667 5 2 3 3.333333333 3.333333333 0.998591786 0.015462458 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004949///cannabinoid receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0038171///cannabinoid signaling pathway+++GO:0045453///bone resorption+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0050881///musculoskeletal movement+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 227327 227327 'B3gnt7' mRNA 670 584 519 14.34 12.3 11.78 14.25 13.28 14.36 12.80666667 13.96333333 766 697 747 591 736.6666667 0.007757534 0.308362716 00533///Glycosaminoglycan biosynthesis - keratan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 227331 227331 'Gigyf2' mRNA 817 877 752 7.58 8.01 7.46 8.78 6.58 7.97 7.683333333 7.776666667 1090 794 957 815.3333333 947 0.094458743 0.203762144 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0043204///perikaryon+++GO:1990635///proximal dendrite GO:0005515///protein binding+++GO:0070064///proline-rich region binding GO:0007631///feeding behavior+++GO:0008344///adult locomotory behavior+++GO:0009791///post-embryonic development+++GO:0016441///posttranscriptional gene silencing+++GO:0017148///negative regulation of translation+++GO:0021522///spinal cord motor neuron differentiation+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0035264///multicellular organism growth+++GO:0044267///cellular protein metabolic process+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050881///musculoskeletal movement+++GO:0050885///neuromuscular process controlling balance+++GO:0061157///mRNA destabilization 227333 227333 'Dgkd' mRNA 1229 1132 1157 9.29 7.93 9.18 8.63 7.72 7.78 8.8 8.043333333 1390 1175.73 1177 1172.666667 1247.576667 0.51166273 0.07517441 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity GO:0006654///phosphatidic acid biosynthetic process+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0010033///response to organic substance+++GO:0015031///protein transport+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation+++GO:0090038///negative regulation of protein kinase C signaling+++GO:2000370///positive regulation of clathrin-dependent endocytosis 227334 227334 'Usp40' mRNA 501 509 527 5.56 5.38 5.81 5.39 4.65 5.29 5.583333333 5.11 579 505 560 512.3333333 548 0.582048336 0.08289656 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability 227357 227357 'Espnl' mRNA 1652 1839 1462 16.16 17.69 15.17 1.22 1.22 1.36 16.34 1.266666667 144 140 155 1651 146.3333333 7.72E-210 -3.5041493 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0007605///sensory perception of sound+++GO:0051017///actin filament bundle assembly 227358 227358 'Erfe' mRNA 5 3 2.21 0.1 0.06 0.05 0.66 0.44 0.62 0.07 0.573333333 38.53 25.37 35.17 3.403333333 33.02333333 4.74E-06 3.283334687 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0042802///identical protein binding GO:0006879///cellular iron ion homeostasis+++GO:0007165///signal transduction+++GO:0019217///regulation of fatty acid metabolic process+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046326///positive regulation of glucose import+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:2000193///positive regulation of fatty acid transport 227377 227377 'Farp2' mRNA 611.2 660.09 606.87 8.44 8.97 8.89 2.59 2.68 2.47 8.766666667 2.58 215.94 217.76 199.04 626.0533333 210.9133333 8.51E-36 -1.583943583 04015///Rap1 signaling pathway+++04520///Adherens junction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding GO:0007155///cell adhesion+++GO:0016322///neuron remodeling+++GO:0016601///Rac protein signal transduction+++GO:0022405///hair cycle process+++GO:0030316///osteoclast differentiation+++GO:0031532///actin cytoskeleton reorganization+++GO:0033623///regulation of integrin activation+++GO:0050790///regulation of catalytic activity+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0071800///podosome assembly 227394 227394 'Slco4c1' mRNA 12 25 15 0.28 0.58 0.37 0.04 0.04 0.04 0.41 0.04 2 2 2 17.33333333 2 0.001285757 -3.121150471 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0015711///organic anion transport+++GO:0030154///cell differentiation+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport 227399 227399 'Ppip5k2' mRNA 516 534 502 4.94 5.06 5.12 4.73 4.41 4.54 5.04 4.56 566 512 524 517.3333333 534 0.837930448 0.033671772 04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033857///diphosphoinositol-pentakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0102092///5-diphosphoinositol pentakisphosphate 3-kinase activity" GO:0006020///inositol metabolic process+++GO:0007605///sensory perception of sound+++GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process 227446 227446 'Relch' mRNA 906 961 869 9.15 9.35 9.34 6.82 5.98 6.3 9.28 6.366666667 795 676 711 912 727.3333333 6.79E-04 -0.338400147 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0055037///recycling endosome GO:0005515///protein binding GO:0006869///lipid transport+++GO:0032367///intracellular cholesterol transport 227449 227449 'Zcchc2' mRNA 353 376 271 2.73 2.88 2.21 3.41 3.02 2.99 2.606666667 3.14 506 439 430 333.3333333 458.3333333 0.001832325 0.45189258 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0008150///biological_process 22746 22746 'Zfp85' mRNA 217.69 194.21 193.5 3.95 3.48 4.26 2.91 2.7 2.98 3.896666667 2.863333333 182.89 161.78 167.34 201.8 170.67 0.211156854 -0.256306725 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227485 227485 'Cdh19' mRNA 607.35 719.55 602 5.66 6.95 5.67 3.91 3.64 3.82 6.093333333 3.79 522.06 416.3 463.39 642.9666667 467.25 1.37E-04 -0.472212341 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 22750 22750 'Zfp9' mRNA 250.12 237.32 239.38 3.37 3.12 3.37 2.67 2.37 2.73 3.286666667 2.59 227.81 202.69 229.71 242.2733333 220.07 0.435456256 -0.154635457 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22751 22751 'Zfp90' mRNA 355 461 383 6.38 8.16 6.94 6.54 5.97 6.73 7.16 6.413333333 418 372 415 399.6666667 401.6666667 0.990823096 -0.003814011 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0043392///negative regulation of DNA binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 227522 227522 'Rpp38' mRNA 1403.71 1222.1 1576.41 29.46 25.66 35.55 27.95 26.23 25.72 30.22333333 26.63333333 1492.52 1360.43 1301.64 1400.74 1384.863333 0.827486163 -0.035313078 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 227525 227525 'Dclre1c' mRNA 648.16 637.14 623.74 9.21 9.09 9.59 15.69 16.15 16.46 9.296666667 16.1 1228.77 1227.68 1242.82 636.3466667 1233.09 1.91E-26 0.942750319 03450///Non-homologous end-joining+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0070419///nonhomologous end joining complex GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0003684///damaged DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0035312///5'-3' exodeoxyribonuclease activity GO:0000723///telomere maintenance+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0030183///B cell differentiation+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0033151///V(D)J recombination+++GO:0036297///interstrand cross-link repair+++GO:0051276///chromosome organization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 227526 227526 'Cdnf' mRNA 42 55 54 0.77 0.99 1.04 0.49 0.37 0.52 0.933333333 0.46 31 23 31.96 50.33333333 28.65333333 0.045123194 -0.844681937 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum GO:0003674///molecular_function+++GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0031175///neuron projection development+++GO:0071542///dopaminergic neuron differentiation 22754 22754 'Zfp92' mRNA 6 1 1 0.08 0.01 0.01 0 0.02 0.02 0.033333333 0.013333333 0 2 2 2.666666667 1.333333333 0.682271078 -0.985483407 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227541 227541 'Camk1d' mRNA 144 136 110 1.13 1.1 0.89 3.33 2.82 2.95 1.04 3.033333333 482 400 430 130 437.3333333 3.34E-28 1.740412367 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007399///nervous system development+++GO:0008152///metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0050766///positive regulation of phagocytosis+++GO:0050773///regulation of dendrite development+++GO:0060267///positive regulation of respiratory burst+++GO:0071622///regulation of granulocyte chemotaxis+++GO:0090023///positive regulation of neutrophil chemotaxis 227545 227545 'Proser2' mRNA 1679 1710 1660 25.54 25.75 26.72 13.56 14.67 13.81 26.00333333 14.01333333 1025 1090 1011 1683 1042 5.69E-18 -0.703180289 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 22755 22755 'Zfp93' mRNA 366.67 310.67 358 5.18 4.29 5.62 2.33 3.12 2.39 5.03 2.613333333 182 242 189.54 345.1133333 204.5133333 1.62E-05 -0.766461304 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22756 22756 'Zfp94' mRNA 257 253 190 5.42 5.25 4.25 1.8 1.79 2.01 4.973333333 1.866666667 98 95 106 233.3333333 99.66666667 7.32E-10 -1.233479626 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22757 22757 'Zkscan5' mRNA 383 366 436 5.87 5.2 6.65 4.32 4.69 4.34 5.906666667 4.45 323 337 309 395 323 0.055016514 -0.306072025 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22758 22758 'Zscan12' mRNA 268 272 325 3.16 3.14 4.03 2.39 2.57 1.97 3.443333333 2.31 235 243 186 288.3333333 221.3333333 0.038771124 -0.398388074 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 227580 227580 'C1ql3' mRNA 6.49 11.09 3.78 0.11 0.19 0.07 0.12 0.09 0.07 0.123333333 0.093333333 8.27 5.75 4.65 7.12 6.223333333 0.863090843 -0.232289244 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0050807///regulation of synapse organization 22759 22759 'Zfp97' mRNA 332.22 344.23 232.62 6.56 6.66 4.86 4.17 3.41 3.54 6.026666667 3.706666667 241.76 193.72 201.14 303.0233333 212.2066667 0.00430067 -0.522201598 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22761 22761 'Zfpm1' mRNA 70 104 51 0.94 1.62 0.79 0.73 0.59 0.77 1.116666667 0.696666667 62 49 64 75 58.33333333 0.347723522 -0.364455475 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003151///outflow tract morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003192///mitral valve formation+++GO:0003195///tricuspid valve formation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0030154///cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030220///platelet formation+++GO:0030851///granulocyte differentiation+++GO:0032091///negative regulation of protein binding+++GO:0032642///regulation of chemokine production+++GO:0032713///negative regulation of interleukin-4 production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0035162///embryonic hemopoiesis+++GO:0035855///megakaryocyte development+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048872///homeostasis of number of cells+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060318///definitive erythrocyte differentiation+++GO:0060319///primitive erythrocyte differentiation+++GO:0060377///negative regulation of mast cell differentiation+++GO:0060412///ventricular septum morphogenesis+++GO:0060413///atrial septum morphogenesis 227612 227612 'Tor4a' mRNA 911.95 1018.47 1026.28 14.52 15.92 17.29 21.1 20.73 20.19 15.91 20.67333333 1528.32 1466.43 1416.83 985.5666667 1470.526667 7.03E-10 0.563712203 GO:0005635///nuclear envelope+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0008150///biological_process 227613 227613 'Tubb4b' mRNA 17149 17778 17330 627.4 641.33 672.64 451.85 447.42 447 647.1233333 448.7566667 14190 13712 13582 17419 13828 2.80E-11 -0.345778448 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0045298///tubulin complex GO:0000166///nucleotide binding+++GO:0003725///double-stranded RNA binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process 227615 227615 'Tmem203' mRNA 267 298 229 19.12 21.12 17.4 21.25 22.26 23.16 19.21333333 22.22333333 340 347 358 264.6666667 348.3333333 0.011858278 0.388768988 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006874///cellular calcium ion homeostasis+++GO:0007283///spermatogenesis 227618 227618 'Lrrc26' mRNA 23 16 22 1.17 0.8 1.19 3.9 5.13 3.48 1.053333333 4.17 88 113 76 20.33333333 92.33333333 3.23E-09 2.170564455 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:0099104///potassium channel activator activity GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity 227619 227619 'Man1b1' mRNA 1239 1284 787 17.94 18.3 12.08 13.47 12.91 13.34 16.10666667 13.24 1069 1003 1027 1103.333333 1033 0.545292962 -0.097251972 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044322///endoplasmic reticulum quality control compartment "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding" "GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0008152///metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0036508///protein alpha-1,2-demannosylation+++GO:0036509///trimming of terminal mannose on B branch+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway" 22762 22762 'Zfpm2' mRNA 29 35 24 0.32 0.37 0.27 0.25 0.2 0.23 0.32 0.226666667 26 21 24 29.33333333 23.66666667 0.594522269 -0.317272245 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003192///mitral valve formation+++GO:0003195///tricuspid valve formation+++GO:0003221///right ventricular cardiac muscle tissue morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048738///cardiac muscle tissue development+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060412///ventricular septum morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:2000020///positive regulation of male gonad development+++GO:2000195///negative regulation of female gonad development" 227620 227620 'Uap1l1' mRNA 741 857 857 24.83 28.3 30.46 83.96 89.88 86.38 27.86333333 86.74 2880 3009 2867 818.3333333 2918.666667 1.01E-100 1.821589575 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0003977///UDP-N-acetylglucosamine diphosphorylase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0070569///uridylyltransferase activity GO:0006048///UDP-N-acetylglucosamine biosynthetic process 227622 227622 'Paxx' mRNA 971 1005 958 50.44 52.91 51.12 50.73 50.79 53.79 51.49 51.77 1078 1032 1078 978 1062.666667 0.279928858 0.107942478 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break+++GO:0043564///Ku70:Ku80 complex+++GO:0070419///nonhomologous end joining complex GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0060090///molecular adaptor activity+++GO:0070182///DNA polymerase binding GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus 227624 227624 'Rabl6' mRNA 1479 1453 904 25.35 24.51 16.44 15.37 19.34 18.03 22.1 17.58 1032 1268 1172 1278.666667 1157.333333 0.380129704 -0.143207525 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding 227627 227627 'Obp2a' mRNA 0 5 1 0 0.49 0.12 0.52 0.27 0.72 0.203333333 0.503333333 6 4.33 9 2 6.443333333 0.274890299 1.66808383 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0036094///small molecule binding GO:0008286///insulin receptor signaling pathway+++GO:0010906///regulation of glucose metabolic process+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0042593///glucose homeostasis+++GO:0045721///negative regulation of gluconeogenesis+++GO:0051055///negative regulation of lipid biosynthetic process 22763 22763 'Zfr' mRNA 3488 3556 3170 40.68 40.96 39.22 33.03 31.64 31.95 40.28666667 32.20666667 3263 3048 3039 3404.666667 3116.666667 0.030188084 -0.138124486 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008270///zinc ion binding GO:0007275///multicellular organism development 227632 227632 'Kcnt1' mRNA 49 37 17 0.39 0.28 0.17 0.14 0.05 0.07 0.28 0.086666667 18 8 9 34.33333333 11.66666667 0.010986007 -1.559518525 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005228///intracellular sodium activated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015271///outward rectifier potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport 227634 227634 'Camsap1' mRNA 569.99 595.94 458.07 4.01 4.19 3.48 2.54 2.71 2.89 3.893333333 2.713333333 395.62 419.32 446.09 541.3333333 420.3433333 0.005142594 -0.370785599 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0036449///microtubule minus-end GO:0005516///calmodulin binding+++GO:0008017///microtubule binding+++GO:0030507///spectrin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0022604///regulation of cell morphogenesis+++GO:0031113///regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031175///neuron projection development 227638 227638 'Qsox2' mRNA 1107 1170 1041 17.57 17.87 17.22 9.75 10.67 10.28 17.55333333 10.23333333 733 767 755 1106 751.6666667 3.17E-10 -0.567048029 GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0003756///protein disulfide isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0016972///thiol oxidase activity GO:0006457///protein folding 22764 22764 'Zfx' mRNA 621 629 564 7.94 6.53 6.18 7.88 7.01 8.17 6.883333333 7.686666667 831 699 779 604.6666667 769.6666667 0.001739298 0.336625627 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0043035///chromatin insulator sequence binding+++GO:0046872///metal ion binding "GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0035264///multicellular organism growth+++GO:0048599///oocyte development+++GO:0048872///homeostasis of number of cells+++GO:0060746///parental behavior" 227644 227644 'Snapc4' mRNA 537 529 519 6.09 5.85 6.16 4 3.61 3.09 6.033333333 3.566666667 408 354 304 528.3333333 355.3333333 1.58E-05 -0.585746443 GO:0005634///nucleus+++GO:0019185///snRNA-activating protein complex GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0003677///DNA binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III 227648 227648 'Sec16a' mRNA 1785 1781 1541 10.69 10.5 9.8 10.4 9.58 10.02 10.33 10 1999 1795 1864 1702.333333 1886 0.086030948 0.137703733 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site GO:0005515///protein binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0048208///COPII vesicle coating+++GO:0050821///protein stabilization+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0072659///protein localization to plasma membrane 227656 227656 'Rexo4' mRNA 830 868 885 20.46 21.1 23.14 20.9 21.73 20.75 21.56666667 21.12666667 973 986 938 861 965.6666667 0.155993484 0.152417539 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity "GO:0000726///non-recombinational repair+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0000738///DNA catabolic process, exonucleolytic+++GO:0006281///DNA repair+++GO:0006364///rRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 227659 227659 'Slc2a6' mRNA 24 30 41 0.64 0.86 1.2 10.01 8.91 10.21 0.9 9.71 431 378 428 31.66666667 412.3333333 3.19E-62 3.686489958 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006110///regulation of glycolytic process+++GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 227671 227671 'Gbgt1' mRNA 51 39 36 1 0.76 0.81 1.07 1.04 1.18 0.856666667 1.096666667 62 56 63 42 60.33333333 0.179056254 0.513181089 00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0046872///metal ion binding+++GO:0047277///globoside alpha-N-acetylgalactosaminyltransferase activity" GO:0001575///globoside metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0030259///lipid glycosylation 227674 227674 'Ddx31' mRNA 256 251 255 4.46 4.4 4.56 4.6 4.35 4.33 4.473333333 4.426666667 306 288 277 254 290.3333333 0.307568882 0.179898641 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0042254///ribosome biogenesis 227682 227682 'Trub2' mRNA 395.9 454.43 426.38 8.29 8.52 9.03 8.71 8.25 7.94 8.613333333 8.3 507.33 469.01 483.17 425.57 486.5033333 0.191135853 0.18190198 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity GO:0001522///pseudouridine synthesis+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0070131///positive regulation of mitochondrial translation+++GO:1990481///mRNA pseudouridine synthesis 227683 227683 'Coq4' mRNA 1115.22 1011.47 1049.02 26.75 23.38 26.6 11.2 12.9 11.98 25.57666667 12.02666667 534.04 560.45 542.24 1058.57 545.5766667 3.09E-22 -0.968685571 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0006744///ubiquinone biosynthetic process 227693 227693 'Zer1' mRNA 485 488 320 6.19 6.14 4.35 3.67 3.67 3.62 5.56 3.653333333 332 329 320 431 327 0.013465703 -0.401969589 GO:0031462///Cul2-RING ubiquitin ligase complex GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 227695 227695 'Spout1' mRNA 1220.48 1159.27 1119.71 38.17 35.73 37.15 27.28 29.06 24.18 37.01666667 26.84 1002.33 1042.43 859.83 1166.486667 968.1966667 0.005870375 -0.280164492 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0072686///mitotic spindle" GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0035198///miRNA binding GO:0007049///cell cycle+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0032259///methylation+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0051301///cell division+++GO:0051661///maintenance of centrosome location 227696 227696 'Phyhd1' mRNA 718 681 645 33.05 31.04 31.68 41.39 42.73 39.38 31.92333333 41.16666667 1059 1058 962 681.3333333 1026.333333 1.23E-09 0.580164876 GO:0005575///cellular_component "GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" 227697 227697 'Dolk' mRNA 1221 1241 1146 32.49 32.52 32.35 26.1 27.3 26.39 32.45333333 26.59666667 1128 1152 1104 1202.666667 1128 0.278669602 -0.103081698 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0004168///dolichol kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0016310///phosphorylation+++GO:0043048///dolichyl monophosphate biosynthetic process 227699 227699 'Nup188' mRNA 568 603 553 5.3 5.54 5.46 5.78 5.41 5.56 5.433333333 5.583333333 714 655 666 574.6666667 678.3333333 0.041298785 0.227629603 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0044611///nuclear pore inner ring GO:0017056///structural constituent of nuclear pore GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051028///mRNA transport 22770 22770 'Zhx1' mRNA 1854 1897 1797 19.25 19.33 19.78 15.96 15.62 14.83 19.45333333 15.47 1771 1690 1592 1849.333333 1684.333333 0.066545751 -0.146765539 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 227700 227700 'Sh3glb2' mRNA 1670 1573 1471 46.1 42.78 43.25 26.38 27.09 27.77 44.04333333 27.08 1056 1041 1087 1571.333333 1061.333333 4.91E-13 -0.576551973 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0042802///identical protein binding GO:0061024///membrane organization 227707 227707 'BC005624' mRNA 1813 1884 1919 82.1 84.06 92.15 71.29 77.37 69.18 86.10333333 72.61333333 1814 1917 1700 1872 1810.333333 0.566320484 -0.061275789 GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0048024///regulation of mRNA splicing, via spliceosome" 22771 22771 'Zic1' mRNA 64 86 58 0.61 0.8 0.6 0.84 0.97 0.97 0.67 0.926666667 101 113 111 69.33333333 108.3333333 0.024192183 0.638281873 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001501///skeletal system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0007628///adult walking behavior+++GO:0008589///regulation of smoothened signaling pathway+++GO:0021510///spinal cord development+++GO:0030154///cell differentiation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042472///inner ear morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 227715 227715 'Exosc2' mRNA 681.65 644.22 646.22 23.29 21.74 23.43 23.14 22.73 21.71 22.82 22.52666667 777.6 751.56 708.5 657.3633333 745.8866667 0.134613551 0.169663371 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0030307///positive regulation of cell growth+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0071034///CUT catabolic process+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071049///nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing" 227717 227717 'Qrfp' mRNA 0 3.15 1.4 0 0.06 0.03 0.1 0.13 0 0.03 0.076666667 6.08 7.48 0 1.516666667 4.52 0.403992017 1.699300916 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0005184///neuropeptide hormone activity+++GO:0031854///orexigenic neuropeptide QRFP receptor binding GO:0007218///neuropeptide signaling pathway+++GO:0007610///behavior+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0045777///positive regulation of blood pressure+++GO:0060259///regulation of feeding behavior 22772 22772 'Zic2' mRNA 153 148 79 2.83 2.7 1.55 2.03 1.8 2.44 2.36 2.09 126 109 147 126.6666667 127.3333333 0.990823096 0.007159511 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding" "GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0007601///visual perception+++GO:0030154///cell differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0044782///cilium organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048066///developmental pigmentation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1900224///positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry" 227720 227720 'Nup214' mRNA 794 773 759 5.72 5.43 5.7 5.68 4.77 5.24 5.616666667 5.23 920 760 819 775.3333333 833 0.464613664 0.090133225 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:1990876///cytoplasmic side of nuclear pore GO:0005049///nuclear export signal receptor activity+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore GO:0000278///mitotic cell cycle+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0015031///protein transport+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0051028///mRNA transport+++GO:0051726///regulation of cell cycle 227721 227721 'Plpp7' mRNA 383 399 445 11.24 11.54 13.84 6.73 7.25 5.92 12.20666667 6.633333333 265 277 224 409 255.3333333 1.02E-05 -0.69503219 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0042577///lipid phosphatase activity GO:0010832///negative regulation of myotube differentiation+++GO:0016311///dephosphorylation 227723 227723 'Prrc2b' mRNA 3352 3361 2793 19.33 18.96 16.85 12.31 12.51 13.34 18.38 12.72 2463 2430 2591 3168.666667 2494.666667 5.53E-07 -0.353138422 GO:0005575///cellular_component GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0030154///cell differentiation 22773 22773 'Zic3' mRNA 40 26 36 0.53 0.34 0.51 0.63 0.7 0.66 0.46 0.663333333 54 59 55 34 56 0.078987261 0.705797172 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001947///heart looping+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0009952///anterior/posterior pattern specification+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0035469///determination of pancreatic left/right asymmetry+++GO:0035545///determination of left/right asymmetry in nervous system+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0071910///determination of liver left/right asymmetry" 227731 227731 'Slc25a25' mRNA 4607.24 4960.38 4650.95 76.24 80 82.11 27.29 27 28.5 79.45 27.59666667 1950.42 1851.29 1924.42 4739.523333 1908.71 1.11E-101 -1.324304297 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0002021///response to dietary excess+++GO:0014823///response to activity+++GO:0015867///ATP transport+++GO:0032094///response to food+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development+++GO:0045333///cellular respiration+++GO:0046034///ATP metabolic process+++GO:0055085///transmembrane transport+++GO:0060612///adipose tissue development+++GO:0070588///calcium ion transmembrane transport 227733 227733 'Pip5kl1' mRNA 3 4 1 0.1 0.1 0.04 0.08 0.14 0.04 0.08 0.086666667 3 5 1 2.666666667 3 0.925724822 0.180504709 00562///Inositol phosphate metabolism+++04144///Endocytosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity GO:0001933///negative regulation of protein phosphorylation+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0016310///phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0043065///positive regulation of apoptotic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation 227736 227736 'Cfap157' mRNA 164.6 165.19 148 5.72 5.66 5.45 0.94 0.81 0.95 5.61 0.9 31.14 26 30.29 159.2633333 29.14333333 1.47E-19 -2.4658334 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0030154///cell differentiation 227737 227737 'Niban2' mRNA 3706 3743 2848 54.4 54.05 44.35 50.91 56.8 56.7 50.93333333 54.80333333 3991 4350 4305 3432.333333 4215.333333 5.45E-04 0.291368783 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0003713///transcription coactivator activity "GO:0008285///negative regulation of cell proliferation+++GO:0032274///gonadotropin secretion+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:2000679///positive regulation of transcription regulatory region DNA binding" 227738 227738 'Lrsam1' mRNA 524 588 612 6.94 7.63 8.63 5.95 5.77 5.67 7.733333333 5.796666667 514 493 475 574.6666667 494 0.082426765 -0.232898792 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0045806///negative regulation of endocytosis+++GO:0046755///viral budding+++GO:0051865///protein autoubiquitination+++GO:0070086///ubiquitin-dependent endocytosis+++GO:1904417///positive regulation of xenophagy+++GO:2000786///positive regulation of autophagosome assembly 22774 22774 'Zic4' mRNA 141 131 120 1.73 1.32 1.53 2.15 2.24 1.96 1.526666667 2.116666667 214 213 184 130.6666667 203.6666667 0.001517598 0.630051475 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development 227743 227743 'Mapkap1' mRNA 939 1006 310 15.48 16.16 5.54 6.22 7.77 8.84 12.39333333 7.61 427 526 594 751.6666667 515.6666667 0.381530071 -0.529391943 04150///mTOR signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031932///TORC2 complex "GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0070300///phosphatidic acid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0006412///translation+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038203///TORC2 signaling+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1900407///regulation of cellular response to oxidative stress 227746 227746 'Rabepk' mRNA 478.54 500.22 494.4 14.58 15.06 15.48 17.23 17.64 15.43 15.04 16.76666667 665.24 673.48 583.69 491.0533333 640.8033333 0.002025115 0.37156859 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane 22775 22775 'Zik1' mRNA 128 153 135 1.64 1.93 1.84 0.9 1.11 0.9 1.803333333 0.97 81 97 78 138.6666667 85.33333333 0.003951686 -0.710281492 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 227753 227753 'Gsn' mRNA 47263 49351 48607 985.06 1012.58 1074.77 525.09 551.81 514.36 1024.136667 530.42 28941 29692 27428 48407 28687 3.27E-42 -0.767408518 04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05203///Viral carcinogenesis GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016528///sarcoplasm+++GO:0030027///lamellipodium+++GO:0030478///actin cap+++GO:0030864///cortical actin cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm "GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0036313///phosphatidylinositol 3-kinase catalytic subunit binding+++GO:0045159///myosin II binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding" "GO:0006911///phagocytosis, engulfment+++GO:0006915///apoptotic process+++GO:0007417///central nervous system development+++GO:0007568///aging+++GO:0008154///actin polymerization or depolymerization+++GO:0010628///positive regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0014891///striated muscle atrophy+++GO:0016192///vesicle-mediated transport+++GO:0030030///cell projection organization+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030042///actin filament depolymerization+++GO:0030155///regulation of cell adhesion+++GO:0031648///protein destabilization+++GO:0035994///response to muscle stretch+++GO:0042060///wound healing+++GO:0042246///tissue regeneration+++GO:0042989///sequestering of actin monomers+++GO:0045010///actin nucleation+++GO:0045471///response to ethanol+++GO:0046597///negative regulation of viral entry into host cell+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0051014///actin filament severing+++GO:0051016///barbed-end actin filament capping+++GO:0051127///positive regulation of actin nucleation+++GO:0051593///response to folic acid+++GO:0051693///actin filament capping+++GO:0055119///relaxation of cardiac muscle+++GO:0060271///cilium assembly+++GO:0071276///cellular response to cadmium ion+++GO:0071346///cellular response to interferon-gamma+++GO:0071801///regulation of podosome assembly+++GO:0086003///cardiac muscle cell contraction+++GO:0090527///actin filament reorganization+++GO:0097017///renal protein absorption+++GO:0097284///hepatocyte apoptotic process+++GO:1902174///positive regulation of keratinocyte apoptotic process+++GO:1903903///regulation of establishment of T cell polarity+++GO:1903906///regulation of plasma membrane raft polarization+++GO:1903909///regulation of receptor clustering+++GO:1903923///positive regulation of protein processing in phagocytic vesicle+++GO:1990000///amyloid fibril formation+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" 22776 22776 'Zim1' mRNA 0 1 1 0 0.02 0.01 0.03 0.01 0.01 0.01 0.016666667 3 1 1 0.666666667 1.666666667 0.662566835 1.290266599 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 22778 22778 'Ikzf1' mRNA 41 29 27 0.44 0.3 0.29 2.7 3.08 3.07 0.343333333 2.95 290 327 324 32.33333333 313.6666667 2.71E-45 3.270065853 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0032993///protein-DNA complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008187///poly-pyrimidine tract binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001779///natural killer cell differentiation+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0010628///positive regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0030098///lymphocyte differentiation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0030900///forebrain development+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0035881///amacrine cell differentiation+++GO:0040018///positive regulation of multicellular organism growth+++GO:0045184///establishment of protein localization+++GO:0045660///positive regulation of neutrophil differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048535///lymph node development+++GO:0048538///thymus development+++GO:0048541///Peyer's patch development+++GO:0048732///gland development+++GO:0051138///positive regulation of NK T cell differentiation+++GO:0060040///retinal bipolar neuron differentiation+++GO:0060041///retina development in camera-type eye" 22779 22779 'Ikzf2' mRNA 369 399 338 2.07 2.19 2.01 1.44 1.15 1.41 2.09 1.333333333 298 231 282 368.6666667 270.3333333 0.002772877 -0.458730282 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 22780 22780 'Ikzf3' mRNA 2 0 2 0.02 0 0.01 0.13 0.05 0.14 0.01 0.106666667 12 6 10 1.333333333 9.333333333 0.034457468 2.779375714 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009617///response to bacterium+++GO:0030888///regulation of B cell proliferation+++GO:0042113///B cell activation+++GO:0042981///regulation of apoptotic process+++GO:0045577///regulation of B cell differentiation+++GO:0045619///regulation of lymphocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 227800 227800 'Rabgap1' mRNA 2368.02 2040.01 2337.93 13.55 12.27 15.01 11.87 10.04 10.51 13.61 10.80666667 1563.81 1365.04 1515.5 2248.653333 1481.45 1.11E-11 -0.617929319 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0007049///cell cycle+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity 227801 227801 'Dennd1a' mRNA 429 416 374 5.34 5.12 4.97 5.18 4.08 5.26 5.143333333 4.84 473 368 468 406.3333333 436.3333333 0.600613626 0.091200919 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030425///dendrite+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0017124///SH3 domain binding+++GO:0031267///small GTPase binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0032483///regulation of Rab protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0050790///regulation of catalytic activity 22781 22781 'Ikzf4' mRNA 271 262 236 2.5 2.36 2.32 1.72 1.28 1.51 2.393333333 1.503333333 210 155 176 256.3333333 180.3333333 0.004279113 -0.51956902 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051260///protein homooligomerization" 22782 22782 'Slc30a1' mRNA 93 97 91 0.95 0.97 0.98 1.73 1.4 1.47 0.966666667 1.533333333 195 154 161 93.66666667 170 1.32E-04 0.846665341 04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity+++GO:0019855///calcium channel inhibitor activity GO:0001701///in utero embryonic development+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0010312///detoxification of zinc ion+++GO:0046929///negative regulation of neurotransmitter secretion+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070574///cadmium ion transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0071584///negative regulation of zinc ion transmembrane import+++GO:0071585///detoxification of cadmium ion+++GO:0090281///negative regulation of calcium ion import+++GO:0098655///cation transmembrane transport 227835 227835 'Gtdc1' mRNA 315.05 311.79 251.66 10.14 9.87 8.69 4.86 4.45 5.03 9.566666667 4.78 167.48 148.32 169.76 292.8333333 161.8533333 3.39E-07 -0.866032185 GO:0005575///cellular_component "GO:0003674///molecular_function+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0008150///biological_process 22784 22784 'Slc30a3' mRNA 30 58 33 0.85 1.63 1 9.97 10.49 10.41 1.16 10.29 403 414 407 40.33333333 408 4.10E-54 3.33164382 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0097457///hippocampal mossy fiber+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0005385///zinc ion transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0010043///response to zinc ion+++GO:0010312///detoxification of zinc ion+++GO:0032119///sequestering of zinc ion+++GO:0051050///positive regulation of transport+++GO:0055085///transmembrane transport+++GO:0061088///regulation of sequestering of zinc ion+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:0099180///zinc ion import into synaptic vesicle 22785 22785 'Slc30a4' mRNA 308 323 259 3.03 3.15 2.74 2.85 2.58 2.45 2.973333333 2.626666667 330 292 274 296.6666667 298.6666667 0.99871387 3.37E-04 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0009636///response to toxic substance+++GO:0010043///response to zinc ion+++GO:0055069///zinc ion homeostasis+++GO:0055085///transmembrane transport+++GO:0061088///regulation of sequestering of zinc ion+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport 22786 22786 'Zp1' mRNA 1 6 0 0.03 0.18 0 0.03 0.03 0 0.07 0.02 1 1 0 2.333333333 0.666666667 0.523671925 -1.780712432 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035805///egg coat+++GO:0062023///collagen-containing extracellular matrix GO:0035804///structural constituent of egg coat GO:0007338///single fertilization 227867 227867 'Epc2' mRNA 264 267 230 3.22 3.19 2.95 2.35 2.24 2.68 3.12 2.423333333 222 206 245 253.6666667 224.3333333 0.327498603 -0.186864665 GO:0005634///nucleus+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0035267///NuA4 histone acetyltransferase complex GO:0004402///histone acetyltransferase activity GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016573///histone acetylation 22788 22788 'Zp3' mRNA 1 3 7 0.05 0.14 0.34 0.12 0.08 0.12 0.176666667 0.106666667 3 2 3 3.666666667 2.666666667 0.79166586 -0.500833007 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0031965///nuclear membrane+++GO:0035805///egg coat+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0032190///acrosin binding+++GO:0035804///structural constituent of egg coat+++GO:0042802///identical protein binding+++GO:0048018///receptor ligand activity "GO:0001809///positive regulation of type IV hypersensitivity+++GO:0001825///blastocyst formation+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0002687///positive regulation of leukocyte migration+++GO:0002922///positive regulation of humoral immune response+++GO:0007165///signal transduction+++GO:0007339///binding of sperm to zona pellucida+++GO:0010469///regulation of signaling receptor activity+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0035803///egg coat formation+++GO:0042102///positive regulation of T cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0048599///oocyte development+++GO:0050729///positive regulation of inflammatory response+++GO:2000344///positive regulation of acrosome reaction+++GO:2000360///negative regulation of binding of sperm to zona pellucida+++GO:2000368///positive regulation of acrosomal vesicle exocytosis+++GO:2000386///positive regulation of ovarian follicle development+++GO:2000388///positive regulation of antral ovarian follicle growth" 22791 22791 'Dnajc2' mRNA 283 355 285 7.88 9.74 8.43 14.27 14.46 14.08 8.683333333 14.27 589 583 563 307.6666667 578.3333333 1.95E-12 0.901042141 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0030544///Hsp70 protein binding+++GO:0042393///histone binding+++GO:0043022///ribosome binding+++GO:0061649///ubiquitin modification-dependent histone binding "GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0006450///regulation of translational fidelity+++GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051083///'de novo' cotranslational protein folding+++GO:2000279///negative regulation of DNA biosynthetic process" 227929 227929 'Cytip' mRNA 11 6 3 0.26 0.14 0.05 2.41 2.01 2.53 0.15 2.316666667 134 111 134 6.666666667 126.3333333 2.17E-22 4.236666713 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005938///cell cortex GO:0030155///regulation of cell adhesion 22793 22793 'Zyx' mRNA 4347.09 4581.88 3508.33 111.05 115.02 95.56 82.74 80.8 85.57 107.21 83.03666667 3688.84 3546.42 3734 4145.766667 3656.42 0.014748322 -0.188009706 04510///Focal adhesion GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0045335///phagocytic vesicle GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0043149///stress fiber assembly+++GO:0050727///regulation of inflammatory response+++GO:0071346///cellular response to interferon-gamma 227933 227933 'Ccdc148' mRNA 562.75 568.94 524.75 4.79 5.14 4.78 0.97 1.1 0.9 4.903333333 0.99 123.1 131 124.74 552.1466667 126.28 8.67E-51 -2.139962307 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 227937 227937 'Pkp4' mRNA 2467 2334 2243 30.71 28.49 29.49 14.32 12.69 13.76 29.56333333 13.59 1333 1139 1242 2348 1238 1.86E-35 -0.935770277 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0030496///midbody+++GO:0044291///cell-cell contact zone+++GO:0048471///perinuclear region of cytoplasm+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle GO:0045296///cadherin binding GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0032467///positive regulation of cytokinesis+++GO:0043547///positive regulation of GTPase activity+++GO:0098609///cell-cell adhesion 227960 227960 'Gca' mRNA 557 608 626 9.25 9.93 11.03 10.3 10.55 8.75 10.07 9.866666667 714 714 587 597 671.6666667 0.269344406 0.155852363 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity 228003 228003 'Klhl41' mRNA 35.85 18.73 22.87 0.79 0.4 0.53 0.56 0.36 0.35 0.573333333 0.423333333 29.53 18.67 17.6 25.81666667 21.93333333 0.73886472 -0.243732274 GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031143///pseudopodium+++GO:0031430///M band+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042995///cell projection GO:0016567///protein ubiquitination+++GO:0030239///myofibril assembly+++GO:0031275///regulation of lateral pseudopodium assembly+++GO:0035914///skeletal muscle cell differentiation+++GO:0045214///sarcomere organization+++GO:0045661///regulation of myoblast differentiation+++GO:0048741///skeletal muscle fiber development+++GO:2000291///regulation of myoblast proliferation+++GO:2001014///regulation of skeletal muscle cell differentiation 228005 228005 'Ppig' mRNA 1185 1132 1121 10.15 9.55 10.21 9.84 9.29 9.28 9.97 9.47 1322 1219 1207 1146 1249.333333 0.242019186 0.112012151 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 228012 228012 'Tlk1' mRNA 722 675 644 9.85 9.07 9.46 6.99 6.78 7.21 9.46 6.993333333 595 555 607 680.3333333 585.6666667 0.044781618 -0.227367851 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001672///regulation of chromatin assembly or disassembly+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006886///intracellular protein transport+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 228019 228019 'Mettl8' mRNA 180.75 193.13 180.58 3.77 4.28 3.92 3.98 4.19 3.61 3.99 3.926666667 208.57 216 185.39 184.82 203.32 0.574413617 0.127923537 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004402///histone acetyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008174///mRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0052735///tRNA (cytosine-3-)-methyltransferase activity GO:0007519///skeletal muscle tissue development+++GO:0016573///histone acetylation+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0045444///fat cell differentiation+++GO:0080009///mRNA methylation 228026 228026 'Pdk1' mRNA 1654.04 1654 1644 17 16.72 17.91 8.86 8.41 8.79 17.21 8.686666667 991 920 953 1650.68 954.6666667 8.00E-24 -0.802882467 04066///HIF-1 signaling pathway+++05230///Central carbon metabolism in cancer GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0045254///pyruvate dehydrogenase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0007166///cell surface receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0097411///hypoxia-inducible factor-1alpha signaling pathway 228033 228033 'Atp5g3' mRNA 2277 2007 2046 224.78 196.61 214.75 239.74 247.97 237.59 212.0466667 241.7666667 2776 2801 2665 2110 2747.333333 9.23E-07 0.369016759 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0033177///proton-transporting two-sector ATPase complex, proton-transporting domain+++GO:0034703///cation channel complex+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" GO:0008289///lipid binding+++GO:0015078///proton transmembrane transporter activity+++GO:0022834///ligand-gated channel activity GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0046931///pore complex assembly+++GO:1902600///proton transmembrane transport 228061 228061 'Agps' mRNA 418 459 425 3 3.23 3.23 4.19 3.81 4.17 3.153333333 4.056666667 674 599 649 434 640.6666667 1.58E-06 0.549663161 00565///Ether lipid metabolism+++04146///Peroxisome GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0016020///membrane GO:0003824///catalytic activity+++GO:0008609///alkylglycerone-phosphate synthase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding GO:0006629///lipid metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0008611///ether lipid biosynthetic process 228071 228071 'Sestd1' mRNA 1789 1760 1778 10.46 10.09 10.98 6.73 5.83 7.09 10.51 6.55 1332 1133 1353 1775.666667 1272.666667 1.25E-08 -0.494246349 GO:0034704///calcium channel complex+++GO:0045111///intermediate filament cytoskeleton "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0070300///phosphatidic acid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:1904878///negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 228094 228094 'Cerkl' mRNA 9 18.45 10 0.3 0.6 0.35 0.56 0.56 0.27 0.416666667 0.463333333 19.44 19.17 9 12.48333333 15.87 0.710332898 0.33933261 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0001727///lipid kinase activity+++GO:0001729///ceramide kinase activity+++GO:0003951///NAD+ kinase activity+++GO:0016301///kinase activity+++GO:0046625///sphingolipid binding GO:0006665///sphingolipid metabolic process+++GO:0016310///phosphorylation+++GO:0030148///sphingolipid biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0046834///lipid phosphorylation 228136 228136 'Zdhhc5' mRNA 915.01 926.62 723.88 10.34 10.29 8.67 11.37 10.02 10.41 9.766666667 10.6 1158.9 997.53 1027.65 855.17 1061.36 0.003498192 0.303008807 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0045335///phagocytic vesicle "GO:0005515///protein binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0018345///protein palmitoylation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905171///positive regulation of protein localization to phagocytic vesicle 228139 228139 'P2rx3' mRNA 38 29 32 0.42 0.32 0.38 0.11 0.16 0.2 0.373333333 0.156666667 12 17 24 33 17.66666667 0.09516042 -0.910686675 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04742///Taste transduction GO:0005639///integral component of nuclear inner membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098794///postsynapse+++GO:0099056///integral component of presynaptic membrane GO:0000166///nucleotide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0001666///response to hypoxia+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007268///chemical synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0009266///response to temperature stimulus+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0009612///response to mechanical stimulus+++GO:0009743///response to carbohydrate+++GO:0010033///response to organic substance+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0019228///neuronal action potential+++GO:0030432///peristalsis+++GO:0033198///response to ATP+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0048167///regulation of synaptic plasticity+++GO:0048266///behavioral response to pain+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050909///sensory perception of taste+++GO:0060079///excitatory postsynaptic potential+++GO:0061368///behavioral response to formalin induced pain+++GO:0070207///protein homotrimerization+++GO:0071318///cellular response to ATP+++GO:0098655///cation transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:1904058///positive regulation of sensory perception of pain 228140 228140 'Tnks1bp1' mRNA 662 722 602 6.12 6.57 5.88 7.27 6.19 7 6.19 6.82 905 748 840 662 831 0.00343336 0.317370522 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0030014///CCR4-NOT complex GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0071532///ankyrin repeat binding GO:0006302///double-strand break repair+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071479///cellular response to ionizing radiation 228151 228151 'Fads2b' mRNA 1 0 0 0.03 0 0 0.03 0 0 0.01 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process 228355 228355 'Madd' mRNA 1257 1258 925 11.1 10.88 8.64 4.48 4.72 5.37 10.20666667 4.856666667 583 600 675 1146.666667 619.3333333 3.43E-15 -0.89355956 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:1904115///axon cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0000187///activation of MAPK activity+++GO:0006915///apoptotic process+++GO:0032483///regulation of Rab protein signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0048490///anterograde synaptic vesicle transport+++GO:0050790///regulation of catalytic activity+++GO:0051726///regulation of cell cycle+++GO:0060125///negative regulation of growth hormone secretion+++GO:0097194///execution phase of apoptosis+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902277///negative regulation of pancreatic amylase secretion+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 228356 228356 '1110051M20Rik' mRNA 1418.52 1426.03 1390.46 41.83 40.57 41.86 23.31 22.65 23.37 41.42 23.11 913.64 865.21 901.7 1411.67 893.5166667 2.37E-16 -0.67260119 GO:0003674///molecular_function GO:0008150///biological_process 228357 228357 'Lrp4' mRNA 461 443.98 389.95 3.5 3.36 3.04 3.17 3.29 3.66 3.3 3.373333333 468.03 494 526.05 431.6433333 496.0266667 0.160414943 0.19397976 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0044853///plasma membrane raft+++GO:0097060///synaptic membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0034185///apolipoprotein binding+++GO:0042803///protein homodimerization activity+++GO:0097110///scaffold protein binding GO:0001822///kidney development+++GO:0001932///regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0006897///endocytosis+++GO:0007275///multicellular organism development+++GO:0008104///protein localization+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030326///embryonic limb morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043113///receptor clustering+++GO:0048699///generation of neurons+++GO:0048813///dendrite morphogenesis+++GO:0048856///anatomical structure development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050771///negative regulation of axonogenesis+++GO:0050808///synapse organization+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0060173///limb development+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1901631///positive regulation of presynaptic membrane organization+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering 228359 228359 'Arhgap1' mRNA 1823.01 1836.95 1895.5 33.94 33.71 37.51 42.02 40.17 37.01 35.05333333 39.73333333 2584.01 2416.01 2211.2 1851.82 2403.74 8.62E-06 0.362488751 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm+++GO:0097443///sorting endosome GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0031267///small GTPase binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0016197///endosomal transport+++GO:0033572///transferrin transport+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:2001136///negative regulation of endocytic recycling 228361 228361 'Ambra1' mRNA 1244 1128 1016 12.98 11.64 11.39 9.45 7.96 8.64 12.00333333 8.683333333 1040 852 921 1129.333333 937.6666667 0.00616813 -0.279313479 04137///Mitophagy - animal+++04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051020///GTPase binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0000423///mitophagy+++GO:0006914///autophagy+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0009267///cellular response to starvation+++GO:0009790///embryo development+++GO:0010508///positive regulation of autophagy+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0021915///neural tube development+++GO:0030154///cell differentiation+++GO:0031667///response to nutrient levels+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0098780///response to mitochondrial depolarisation 228366 228366 'Large2' mRNA 726 684 656 16.67 15.39 15.93 12.59 13.54 12.36 15.99666667 12.83 627 663 600 688.6666667 630 0.253184887 -0.13907539 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0002162///dystroglycan binding+++GO:0003824///catalytic activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042285///xylosyltransferase activity+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008152///metabolic process+++GO:0035269///protein O-linked mannosylation 228368 228368 'Slc35c1' mRNA 412 376 277 7.99 7.12 5.47 13.01 10.93 11.25 6.86 11.73 756 627 650 355 677.6666667 8.78E-12 0.925443859 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005457///GDP-fucose transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008643///carbohydrate transport+++GO:0030259///lipid glycosylation+++GO:0036066///protein O-linked fucosylation+++GO:0036085///GDP-fucose import into Golgi lumen+++GO:0045746///negative regulation of Notch signaling pathway 228410 228410 'Cstf3' mRNA 898 990 909 29.08 32.28 30.21 27.33 25.01 28.92 30.52333333 27.08666667 998 891 987 932.3333333 958.6666667 0.836000484 0.028133997 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003729///mRNA binding GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0031123///RNA 3'-end processing 228413 228413 'Prrg4' mRNA 341 362 303 4.48 4.38 4.14 7.42 6.66 7 4.333333333 7.026666667 739 624.03 668.68 335.3333333 677.2366667 1.64E-17 1.002943881 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0005509///calcium ion binding+++GO:0050699///WW domain binding GO:0008150///biological_process 228421 228421 'Kif18a' mRNA 56 76 86 0.91 1.21 1.48 1.26 1.37 1.55 1.2 1.393333333 89 95 107 72.66666667 97 0.213846137 0.400461489 GO:0000776///kinetochore+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005828///kinetochore microtubule+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005901///caveola+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection+++GO:0061673///mitotic spindle astral microtubule+++GO:1990023///mitotic spindle midzone "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0051010///microtubule plus-end binding+++GO:0070463///tubulin-dependent ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0000070///mitotic sister chromatid segregation+++GO:0007018///microtubule-based movement+++GO:0007019///microtubule depolymerization+++GO:0007080///mitotic metaphase plate congression+++GO:0007140///male meiotic nuclear division+++GO:0015031///protein transport+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0072520///seminiferous tubule development 228432 228432 'Ano3' mRNA 1368 1496.94 1456 16.58 17.12 17.12 1.18 1.55 1.7 16.94 1.476666667 107 110 143 1440.313333 120 2.95E-176 -3.597354251 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity+++GO:0046983///protein dimerization activity GO:0006869///lipid transport+++GO:0016048///detection of temperature stimulus+++GO:0050982///detection of mechanical stimulus+++GO:0055085///transmembrane transport+++GO:0061588///calcium activated phospholipid scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:1902476///chloride transmembrane transport 228482 228482 'Arhgap11a' mRNA 21 21 41 0.22 0.22 0.46 2.88 2.92 2.66 0.3 2.82 311 308 279 27.66666667 299.3333333 6.03E-40 3.415464026 GO:0005634///nucleus+++GO:0005759///mitochondrial matrix GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity 228491 228491 'Zfp770' mRNA 90 119 89 1.13 1.48 1.19 1.09 1.03 1.18 1.266666667 1.1 100 92 105 99.33333333 99 0.972341361 -0.013519916 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 228536 228536 'Bahd1' mRNA 150 143 103 1.82 1.74 1.35 2.42 2.35 2.43 1.636666667 2.4 227 215 220 132 220.6666667 2.07E-04 0.735032014 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005694///chromosome GO:0003682///chromatin binding "GO:0006325///chromatin organization+++GO:0031507///heterochromatin assembly+++GO:0045892///negative regulation of transcription, DNA-templated" 228543 228543 'Rhov' mRNA 61 74 54 2.14 2.56 2.01 2.23 2.45 3.13 2.236666667 2.603333333 73 78 99 63 83.33333333 0.236361545 0.3972345 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0030031///cell projection assembly+++GO:0032488///Cdc42 protein signal transduction 228545 228545 'Vps18' mRNA 759 740 813 10.1 9.68 11.47 13.92 12.35 12.85 10.41666667 13.04 1195 1041 1077 770.6666667 1104.333333 7.33E-07 0.503472902 05132///Salmonella infection GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030897///HOPS complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0033263///CORVET complex+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019905///syntaxin binding+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006914///autophagy+++GO:0007032///endosome organization+++GO:0007033///vacuole organization+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016567///protein ubiquitination+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035542///regulation of SNARE complex assembly+++GO:0046718///viral entry into host cell+++GO:0048284///organelle fusion+++GO:2000300///regulation of synaptic vesicle exocytosis 228550 228550 'Itpka' mRNA 12 15 6 0.38 0.47 0.2 0.06 0.23 0.11 0.35 0.133333333 2 8 4 11 4.666666667 0.243107421 -1.225199928 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043197///dendritic spine "GO:0000166///nucleotide binding+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding" GO:0006020///inositol metabolic process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0032958///inositol phosphate biosynthetic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048167///regulation of synaptic plasticity+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0097062///dendritic spine maintenance 228564 228564 'Frmd5' mRNA 133 128 92 2.26 1.41 1.29 0.3 0.5 0.17 1.653333333 0.323333333 19 30 17 117.6666667 22 7.99E-13 -2.421929333 GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005178///integrin binding+++GO:0008092///cytoskeletal protein binding+++GO:0019901///protein kinase binding GO:0030334///regulation of cell migration+++GO:0031032///actomyosin structure organization+++GO:0045785///positive regulation of cell adhesion+++GO:2000146///negative regulation of cell motility 228576 228576 'Mall' mRNA 598 632 465 17.34 18.06 14.3 19.83 21.39 18.61 16.56666667 19.94333333 786 828 714 565 776 1.82E-04 0.451778218 GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft GO:0019911///structural constituent of myelin sheath GO:0042552///myelination 228592 228592 'F830045P16Rik' mRNA 1 0 1 0.03 0 0.03 0.03 0.05 0.1 0.02 0.06 1 2 6 0.666666667 3 0.347739005 2.150981003 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 228598 228598 'Ebf4' mRNA 95 83 51 2.45 1.99 1.29 0.91 0.91 0.69 1.91 0.836666667 45 44 32 76.33333333 40.33333333 0.011384485 -0.922765406 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 228602 228602 '4930402H24Rik' mRNA 1975.01 2055.99 1909 15.48 15.79 15.85 12.09 10.37 11.51 15.70666667 11.32333333 1751 1476.99 1621 1980 1616.33 9.31E-05 -0.305344543 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 228607 228607 'Mavs' mRNA 1596 1634 1504 30.22 30.51 30.16 26.67 28.14 29.15 30.29666667 27.98666667 1633 1652 1712 1578 1665.666667 0.457326402 0.067490349 04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0035591///signaling adaptor activity+++GO:0050700///CARD domain binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0007165///signal transduction+++GO:0032481///positive regulation of type I interferon production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0039529///RIG-I signaling pathway+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042742///defense response to bacterium+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0071360///cellular response to exogenous dsRNA+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:0071660///positive regulation of IP-10 production+++GO:1900063///regulation of peroxisome organization 228608 228608 'Smox' mRNA 1673 1733 1603 46.66 46.96 47.28 43.09 48.52 45.61 46.96666667 45.74 1757 1908 1817 1669.666667 1827.333333 0.163383885 0.119988791 00330///Arginine and proline metabolism+++00410///beta-Alanine metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity+++GO:0052894///norspermine:oxygen oxidoreductase activity+++GO:0052895///N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity+++GO:0052901///spermine:oxygen oxidoreductase (spermidine-forming) activity GO:0006598///polyamine catabolic process+++GO:0046208///spermine catabolic process 228662 228662 'Btbd3' mRNA 910 860 843 9.51 8.93 9.46 7.28 7.42 6.8 9.3 7.166666667 803 796 719 871 772.6666667 0.083743676 -0.18455471 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0042802///identical protein binding GO:0007399///nervous system development+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0048813///dendrite morphogenesis 228677 228677 'Sptlc3' mRNA 122 138 120 3.08 3.43 3.21 0.82 0.72 0.68 3.24 0.74 37 31 30 126.6666667 32.66666667 6.58E-12 -1.966670436 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex "GO:0003824///catalytic activity+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding" GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0009058///biosynthetic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0046520///sphingoid biosynthetic process 228714 228714 'Kat14' mRNA 397 418.77 431 5.74 5.97 6.83 6.38 5.13 5.09 6.18 5.533333333 482 390 382 415.59 418 0.978276716 -0.006272315 GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0009790///embryo development+++GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation 228715 228715 'Smim26' mRNA 229 213 276 44.71 41.71 57.23 38.2 40.13 45.66 47.88333333 41.33 222 226 255 239.3333333 234.3333333 0.863090843 -0.04763316 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 228730 228730 'Kiz' mRNA 1333 1339 1277 34.21 33.81 34.97 14.92 14.39 14.45 34.33 14.58666667 680 648 641 1316.333333 656.3333333 2.02E-32 -1.015845737 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0019901///protein kinase binding GO:0007051///spindle organization 228756 228756 'Cstl1' mRNA 0 1 1 0 0.12 0.13 0.11 0 0.11 0.083333333 0.073333333 1 0 1 0.666666667 0.666666667 0.998591786 -0.032941419 GO:0005576///extracellular region GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 228765 228765 'Sdcbp2' mRNA 6 5 11 0.26 0.21 0.5 1.71 1.08 1.58 0.323333333 1.456666667 46 30 42 7.333333333 39.33333333 3.84E-05 2.39786634 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" GO:0008283///cell proliferation 228767 228767 'Tmem74bos' mRNA 0 2 4 0 0.06 0.13 0 0 0 0.063333333 0 0 0 0 2 0 0.282926929 -3.488173787 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 228769 228769 'Psmf1' mRNA 1574.93 1629.77 1532.8 27.43 27.8 28.76 17.15 17.63 16.79 27.99666667 17.19 1123.64 1123.63 1059.33 1579.166667 1102.2 1.67E-11 -0.530126319 03050///Proteasome GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0004866///endopeptidase inhibitor activity+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0070628///proteasome binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1901799///negative regulation of proteasomal protein catabolic process 228770 228770 'Rspo4' mRNA 0 0 2 0 0 0.09 0 0 0 0.03 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04310///Wnt signaling pathway GO:0005576///extracellular region GO:0008201///heparin binding GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0035878///nail development+++GO:0050896///response to stimulus 228775 228775 'Trib3' mRNA 211 242 244 5.84 6.6 7.17 5.42 6.91 5.52 6.536666667 5.95 225 280 222 232.3333333 242.3333333 0.857029762 0.048859803 04931///Insulin resistance GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0055106///ubiquitin-protein transferase regulator activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0010506///regulation of autophagy+++GO:0010827///regulation of glucose transmembrane transport+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043405///regulation of MAP kinase activity+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" 228777 228777 'Nrsn2' mRNA 1 0 0 0.05 0 0 0.08 0 0.13 0.016666667 0.07 2 0 3 0.333333333 1.666666667 0.509095757 2.198366096 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0007399///nervous system development 228778 228778 '6820408C15Rik' mRNA 80 96 79 2.82 3.21 3.16 0.45 0.62 0.37 3.063333333 0.48 17 19 13 85 16.33333333 2.02E-10 -2.388971428 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 228785 228785 'Mylk2' mRNA 52 49 41 0.97 0.9 0.81 0.13 0.1 0.15 0.893333333 0.126666667 8 6 9 47.33333333 7.666666667 4.54E-07 -2.635255979 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004687///myosin light chain kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0032027///myosin light chain binding GO:0006468///protein phosphorylation+++GO:0006833///water transport+++GO:0006937///regulation of muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007274///neuromuscular synaptic transmission+++GO:0010628///positive regulation of gene expression+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031448///positive regulation of fast-twitch skeletal muscle fiber contraction+++GO:0032971///regulation of muscle filament sliding+++GO:0035914///skeletal muscle cell differentiation+++GO:0043408///regulation of MAPK cascade+++GO:0046777///protein autophosphorylation+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048489///synaptic vesicle transport+++GO:0051726///regulation of cell cycle+++GO:0055007///cardiac muscle cell differentiation+++GO:0055008///cardiac muscle tissue morphogenesis 228787 228787 'Xkr7' mRNA 36 30 45 0.29 0.22 0.36 0.02 0.08 0.06 0.29 0.053333333 3 11 9 37 7.666666667 1.61E-04 -2.285233812 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0043652///engulfment of apoptotic cell+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:1902742///apoptotic process involved in development 228788 228788 'Ccm2l' mRNA 14 9 15 0.35 0.22 0.39 0.42 0.57 0.39 0.32 0.46 19 25 17 12.66666667 20.33333333 0.347203853 0.666469622 GO:0005575///cellular_component GO:0005515///protein binding GO:0003007///heart morphogenesis+++GO:0003209///cardiac atrium morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0032091///negative regulation of protein binding+++GO:0034111///negative regulation of homotypic cell-cell adhesion+++GO:0042060///wound healing+++GO:0055017///cardiac muscle tissue growth+++GO:0090271///positive regulation of fibroblast growth factor production 228790 228790 'Asxl1' mRNA 658 660 632 5.34 5.32 5.51 5.22 5.24 5.49 5.39 5.316666667 734 719 743 650 732 0.150262304 0.159922215 GO:0005634///nucleus+++GO:0035517///PR-DUB complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046872///metal ion binding "GO:0000902///cell morphogenesis+++GO:0003007///heart morphogenesis+++GO:0006325///chromatin organization+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009887///animal organ morphogenesis+++GO:0010888///negative regulation of lipid storage+++GO:0030097///hemopoiesis+++GO:0032526///response to retinoic acid+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0035564///regulation of kidney size+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0048534///hematopoietic or lymphoid organ development+++GO:0048538///thymus development+++GO:0048539///bone marrow development+++GO:0048872///homeostasis of number of cells+++GO:0060348///bone development+++GO:0060430///lung saccule development+++GO:0072015///glomerular visceral epithelial cell development" 228796 228796 'Bpifb6' mRNA 0 0 2 0 0 0.08 0 0.24 0.03 0.026666667 0.09 0 7 1 0.666666667 2.666666667 0.482869597 1.958738881 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0008289///lipid binding GO:0008150///biological_process 228801 228801 'Bpifb1' mRNA 1 5 2 0.04 0.18 0.08 0.09 0.03 0 0.1 0.04 3 1 0 2.666666667 1.333333333 0.669092149 -1.012687222 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0008289///lipid binding GO:0002227///innate immune response in mucosa+++GO:0002376///immune system process+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response 228802 228802 'Bpifb5' mRNA 31 23 40 1.15 0.87 1.51 0.12 0.27 0.31 1.176666667 0.233333333 4 8 9 31.33333333 7 6.15E-04 -2.18128145 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0008150///biological_process 228807 228807 'Zfp341' mRNA 80 57 72 1.36 0.95 1.29 0.88 1.04 1.03 1.2 0.983333333 60 69 68 69.66666667 65.66666667 0.821312874 -0.098342848 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0003674///molecular_function+++GO:0003677///DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045893///positive regulation of transcription, DNA-templated" 228812 228812 'Pigu' mRNA 773 780 766 27.91 27.72 29.32 33.18 31.69 31.19 28.31666667 32.02 1056 985 960 773 1000.333333 1.42E-04 0.359285984 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042765///GPI-anchor transamidase complex GO:0034235///GPI anchor binding GO:0006506///GPI anchor biosynthetic process+++GO:0016255///attachment of GPI anchor to protein+++GO:0034394///protein localization to cell surface+++GO:0046425///regulation of JAK-STAT cascade 228829 228829 'Phf20' mRNA 1956 2137 1992 18.24 19.57 19.67 17.11 16.86 17.21 19.16 17.06 2115 2038 2058 2028.333333 2070.333333 0.863090843 0.017716392 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0044545///NSL complex+++GO:0071339///MLL1 complex GO:0003677///DNA binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation" 228836 228836 'Dlgap4' mRNA 2772.73 2621.76 2511.62 37.19 35 36.89 24.74 25.34 26.09 36.36 25.39 2204.35 2141.01 2224.63 2635.37 2189.996667 4.08E-05 -0.278067471 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0098981///cholinergic synapse+++GO:0099572///postsynaptic specialization GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0060090///molecular adaptor activity GO:0023052///signaling+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity 228839 228839 'Tgif2' mRNA 469 503 404 8.79 9.5 8.2 7.58 7.35 7.19 8.83 7.373333333 446 426 413 458.6666667 428.3333333 0.478173058 -0.107447624 04350///TGF-beta signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010470///regulation of gastrulation+++GO:0038092///nodal signaling pathway+++GO:0045666///positive regulation of neuron differentiation+++GO:0060041///retina development in camera-type eye" 228846 228846 'D630003M21Rik' mRNA 318 385 348 4.38 5.22 5.08 6.26 5.41 5.65 4.893333333 5.773333333 522 441 456 350.3333333 473 0.002560218 0.420082301 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 228850 228850 'Ralgapb' mRNA 596 558 481 4.06 3.63 3.59 3.81 3.23 3.47 3.76 3.503333333 643 536 565 545 581.3333333 0.579436716 0.082831284 GO:0005829///cytosol GO:0005096///GTPase activator activity+++GO:0046982///protein heterodimerization activity GO:0032484///Ral protein signal transduction+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0060178///regulation of exocyst localization+++GO:0090630///activation of GTPase activity 228852 228852 'Ppp1r16b' mRNA 430.58 289.56 424.45 3.59 2.36 3.75 4.01 4.6 4.16 3.233333333 4.256666667 554.98 622.95 559.09 381.53 579.0066667 4.17E-04 0.585621968 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0008157///protein phosphatase 1 binding+++GO:0017020///myosin phosphatase regulator activity+++GO:0019888///protein phosphatase regulator activity GO:0001938///positive regulation of endothelial cell proliferation+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0035304///regulation of protein dephosphorylation+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0051489///regulation of filopodium assembly+++GO:0061028///establishment of endothelial barrier+++GO:1902309///negative regulation of peptidyl-serine dephosphorylation+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1903670///regulation of sprouting angiogenesis 228858 228858 'Gdap1l1' mRNA 194 176 205 4.25 3.81 4.85 0.83 0.5 0.77 4.303333333 0.7 42 25 40 191.6666667 35.66666667 2.44E-20 -2.443589888 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006749///glutathione metabolic process 228859 228859 'Fitm2' mRNA 251 255 264 8.91 8.92 9.94 7.91 7.91 6.42 9.256666667 7.413333333 256 250 201.21 256.6666667 235.7366667 0.51328338 -0.136956778 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0010945///CoA pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0017129///triglyceride binding+++GO:0019992///diacylglycerol binding GO:0006629///lipid metabolic process+++GO:0007010///cytoskeleton organization+++GO:0008654///phospholipid biosynthetic process+++GO:0010866///regulation of triglyceride biosynthetic process+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0019915///lipid storage+++GO:0022604///regulation of cell morphogenesis+++GO:0030730///sequestering of triglyceride+++GO:0034389///lipid droplet organization+++GO:0035356///cellular triglyceride homeostasis+++GO:0036115///fatty-acyl-CoA catabolic process+++GO:0055088///lipid homeostasis+++GO:0140042///lipid droplet formation 228866 228866 'Pcif1' mRNA 1757 1713 1669 30.2 29.19 30.44 18.12 19.49 19.12 29.94333333 18.91 1226 1254 1228 1713 1236 3.75E-10 -0.48228875 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge GO:0008168///methyltransferase activity+++GO:0016422///mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0099122///RNA polymerase II C-terminal domain binding+++GO:1904047///S-adenosyl-L-methionine binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding GO:0010923///negative regulation of phosphatase activity+++GO:0017148///negative regulation of translation+++GO:0032259///methylation+++GO:0045727///positive regulation of translation+++GO:0080009///mRNA methylation 228869 228869 'Ncoa5' mRNA 542 549 345 8.96 8.87 5.98 5.45 5.12 5.26 7.936666667 5.276666667 385 343 351 478.6666667 359.6666667 0.011195854 -0.415900374 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton GO:0003682///chromatin binding GO:0042593///glucose homeostasis+++GO:0046627///negative regulation of insulin receptor signaling pathway 228875 228875 'Slc35c2' mRNA 1014 1069 1023 28.98 30.21 31.26 34.94 32.82 34.42 30.15 34.06 1394 1294 1322 1035.333333 1336.666667 2.20E-05 0.356135473 GO:0005654///nucleoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0015297///antiporter activity GO:0010629///negative regulation of gene expression+++GO:0015786///UDP-glucose transmembrane transport+++GO:0036065///fucosylation+++GO:0036066///protein O-linked fucosylation+++GO:0045747///positive regulation of Notch signaling pathway 228876 228876 'Zfp334' mRNA 320 326 221 2.13 2.31 1.52 0.99 1.17 1.21 1.986666667 1.123333333 174 198 200 289 190.6666667 0.001186638 -0.603197896 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 228880 228880 'Zmynd8' mRNA 1996.23 1920.05 2040.04 24.94 22.98 26.91 24 24.7 24.64 24.94333333 24.44666667 2003.04 2014.59 1979.99 1985.44 1999.206667 0.97548262 -0.003882902 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft GO:0003714///transcription corepressor activity+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0019904///protein domain specific binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0070577///lysine-acetylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0016310///phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051491///positive regulation of filopodium assembly+++GO:0060999///positive regulation of dendritic spine development+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:1902952///positive regulation of dendritic spine maintenance" 228889 228889 'Ddx27' mRNA 770 656 663 16.5 13.84 15.07 15.11 17.26 14.84 15.13666667 15.73666667 811 905 771 696.3333333 829 0.045389507 0.241138437 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 228911 228911 'Tshz2' mRNA 5110 5141 4710 51.1 50.58 50.01 23.55 22.49 23.22 50.56333333 23.08666667 2732 2539 2607 4987 2626 9.80E-64 -0.936415317 04391///Hippo signaling pathway - fly GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression 228913 228913 'Zfp217' mRNA 318 287 196 2.81 2.43 1.74 2.73 2.58 2.72 2.326666667 2.676666667 374 333 348 267 351.6666667 0.027150483 0.392427161 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0016607///nuclear speck "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007569///cell aging+++GO:0045892///negative regulation of transcription, DNA-templated" 228942 228942 'Cbln4' mRNA 533 583 553 10.51 11.32 11.57 0.21 0.33 0.39 11.13333333 0.31 12 19 22 556.3333333 17.66666667 7.33E-93 -4.988178217 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding GO:0009306///protein secretion+++GO:0099558///maintenance of synapse structure+++GO:1904862///inhibitory synapse assembly 228960 228960 'Stx16' mRNA 630 631 569 9.22 9.11 8.91 10.33 8.34 9.34 9.08 9.336666667 808 641 712 610 720.3333333 0.054381345 0.227769694 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031985///Golgi cisterna+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding "GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048278///vesicle docking+++GO:0061025///membrane fusion+++GO:0090161///Golgi ribbon formation" 228961 228961 'Npepl1' mRNA 740 738 593 19.99 19.64 16.98 15.13 17.58 18.76 18.87 17.15666667 644 731 773 690.3333333 716 0.772358308 0.046419244 GO:0005737///cytoplasm GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0008150///biological_process+++GO:0019538///protein metabolic process 228966 228966 'Ppp1r3d' mRNA 20.1 40.76 21.03 0.34 0.67 0.37 1.05 0.51 0.9 0.46 0.82 72.03 34.5 59.61 27.29666667 55.38 0.028721858 1.017165658 04910///Insulin signaling pathway+++04931///Insulin resistance GO:0000164///protein phosphatase type 1 complex+++GO:0042587///glycogen granule+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019899///enzyme binding+++GO:2001069///glycogen binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006470///protein dephosphorylation 228980 228980 'Taf4' mRNA 156 145 151 1.89 1.72 1.93 2.2 1.62 2.11 1.846666667 1.976666667 209 151 195 150.6666667 185 0.21665258 0.28131223 03022///Basal transcription factors+++05016///Huntington disease GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0033276///transcription factor TFTC complex+++GO:0071339///MLL1 complex GO:0001046///core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046982///protein heterodimerization activity "GO:0001541///ovarian follicle development+++GO:0006351///transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter" 228983 228983 'Osbpl2' mRNA 1431 1556 1272 27.98 29.99 26.45 19.76 22.39 20.23 28.14 20.79333333 1165 1289 1150 1419.666667 1201.333333 0.008199213 -0.248636771 GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0120020///intermembrane cholesterol transfer activity" GO:0006869///lipid transport+++GO:0007009///plasma membrane organization+++GO:0015914///phospholipid transport+++GO:0030301///cholesterol transport+++GO:0032367///intracellular cholesterol transport+++GO:0051289///protein homotetramerization+++GO:0120009///intermembrane lipid transfer 228993 228993 'Slc17a9' mRNA 25 17 18 0.64 0.45 0.49 1.7 1.95 2.39 0.526666667 2.013333333 76 83 103 20 87.33333333 8.20E-09 2.117509925 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0042584///chromaffin granule membrane GO:0001409///guanine nucleotide transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006887///exocytosis+++GO:0015866///ADP transport+++GO:0015867///ATP transport+++GO:0055085///transmembrane transport+++GO:1903790///guanine nucleotide transmembrane transport+++GO:1904669///ATP export 228994 228994 'Ythdf1' mRNA 414 401 353 7.14 6.81 6.46 8.2 6.83 7.93 6.803333333 7.653333333 547 445 512 389.3333333 501.3333333 0.00770427 0.353749256 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0043022///ribosome binding+++GO:1990247///N6-methyladenosine-containing RNA binding GO:0002376///immune system process+++GO:0002577///regulation of antigen processing and presentation+++GO:0007612///learning+++GO:0007613///memory+++GO:0034063///stress granule assembly+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation+++GO:0045948///positive regulation of translational initiation+++GO:0061157///mRNA destabilization+++GO:0070925///organelle assembly+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1902667///regulation of axon guidance 228998 228998 'Arfgap1' mRNA 1168 1224 1147 23.54 24.04 24.74 26.04 25.37 26.2 24.10666667 25.87 1471 1404 1445 1179.666667 1440 6.10E-04 0.27605818 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0014069///postsynaptic density+++GO:0045202///synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030100///regulation of endocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0043547///positive regulation of GTPase activity 229003 229003 'Helz2' mRNA 422 418 331 2.18 2.13 1.82 3.15 3.05 3.5 2.043333333 3.233333333 701 663 757 390.3333333 707 9.60E-13 0.849216445 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0004540///ribonuclease activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090501///RNA phosphodiester bond hydrolysis" 229004 229004 'Gmeb2' mRNA 817.56 798.84 669.97 8.99 8.49 8.59 14.61 15.88 13.75 8.69 14.74666667 1347.6 1430.98 1236.01 762.1233333 1338.196667 3.89E-17 0.805042728 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 229007 229007 'Zgpat' mRNA 1380.33 1417.07 1341 37.53 37.99 38.57 26.16 26.4 26.86 38.03 26.47333333 1104.06 1100.4 1098.07 1379.466667 1100.843333 3.40E-05 -0.336984484 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0045892///negative regulation of transcription, DNA-templated" 229011 229011 'Samd10' mRNA 842 810 869 21.52 20.48 23.71 16.65 15.35 16.61 21.90333333 16.20333333 747 670 721 840.3333333 712.6666667 0.021131429 -0.252230501 GO:0009898///cytoplasmic side of plasma membrane GO:0003674///molecular_function GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway 229055 229055 'Zbtb10' mRNA 257 240 236 1.82 1.67 1.77 1.83 1.36 1.71 1.753333333 1.633333333 297 217 270 244.3333333 261.3333333 0.716186228 0.083285974 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 229096 229096 'Ythdf3' mRNA 1427 1537 1456 15.53 16.26 16.87 16.54 15.37 15.84 16.22 15.91666667 1769 1595 1645 1473.333333 1669.666667 0.044220374 0.167787189 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0043022///ribosome binding+++GO:1990247///N6-methyladenosine-containing RNA binding GO:0034063///stress granule assembly+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation+++GO:0045948///positive regulation of translational initiation+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061157///mRNA destabilization+++GO:0070925///organelle assembly+++GO:1901163///regulation of trophoblast cell migration 229211 229211 'Acad9' mRNA 797.11 884.91 795.41 12.31 13.71 13.29 13.26 13.94 14.04 13.10333333 13.74666667 925.53 885.46 933.71 825.81 914.9 0.194024722 0.13665071 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031966///mitochondrial membrane "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004466///long-chain-acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0070991///medium-chain-acyl-CoA dehydrogenase activity" GO:0001676///long-chain fatty acid metabolic process+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0051791///medium-chain fatty acid metabolic process 229214 229214 'Qrfpr' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097730///non-motile cilium GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 229227 229227 '4932438A13Rik' mRNA 2147 2215 1871 7 7.1 6.48 5.17 4.46 4.84 6.86 4.823333333 1822 1535 1652 2077.666667 1669.666667 3.71E-05 -0.325725115 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098793///presynapse GO:0003674///molecular_function GO:0001558///regulation of cell growth+++GO:0006113///fermentation+++GO:0006629///lipid metabolic process+++GO:0006909///phagocytosis+++GO:0007283///spermatogenesis+++GO:0016197///endosomal transport+++GO:0019915///lipid storage+++GO:0032456///endocytic recycling+++GO:0045444///fat cell differentiation+++GO:0048488///synaptic vesicle endocytosis+++GO:0051647///nucleus localization+++GO:0060612///adipose tissue development 229228 229228 'Nudt6' mRNA 101.37 88.32 82.73 3.65 4.11 3.64 4.72 6.1 5.26 3.8 5.36 120.53 149.73 120.51 90.80666667 130.2566667 0.046948407 0.513272874 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0047631///ADP-ribose diphosphatase activity+++GO:0051287///NAD binding GO:0008285///negative regulation of cell proliferation+++GO:0045786///negative regulation of cell cycle 229277 229277 'Stoml3' mRNA 0 4 2 0 0.1 0.06 0.05 0.05 0.05 0.053333333 0.05 2 2.07 2 2 2.023333333 0.998591786 -0.006805038 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0005515///protein binding GO:0007165///signal transduction 229279 229279 'Hnrnpa3' mRNA 4487 4309 3649 62.11 57.77 52.32 57.77 47.86 55.62 57.4 53.75 5348 4499 5046 4148.333333 4964.333333 7.14E-04 0.249378289 03040///Spliceosome+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0035770///ribonucleoprotein granule+++GO:0043005///neuron projection+++GO:0071013///catalytic step 2 spliceosome+++GO:1990124///messenger ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0051033///RNA transmembrane transporter activity GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0051028///mRNA transport 229285 229285 'Spg20' mRNA 2644 2803 2542 37.55 39.46 38.96 23.59 25.07 25.11 38.65666667 24.59 1888 1963 1952 2663 1934.333333 4.12E-12 -0.471506507 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030496///midbody+++GO:0045202///synapse GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0000910///cytokinesis+++GO:0009838///abscission+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0034389///lipid droplet organization+++GO:0048698///negative regulation of collateral sprouting in absence of injury+++GO:0050905///neuromuscular process+++GO:0051301///cell division+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060612///adipose tissue development 229302 229302 'Tm4sf4' mRNA 0 3 0 0 0.13 0 0.3 0.15 0.15 0.043333333 0.2 8 4 4 1 5.333333333 0.177235328 2.422913951 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0042246///tissue regeneration 229317 229317 'Eif2a' mRNA 441 521 390 10.7 12.27 10.04 11.93 10.12 12.09 11.00333333 11.38 569 471 553 450.6666667 531 0.10913213 0.227850005 GO:0005737///cytoplasm+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0022627///cytosolic small ribosomal subunit GO:0000049///tRNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0009967///positive regulation of signal transduction+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032933///SREBP signaling pathway+++GO:0042255///ribosome assembly+++GO:1990928///response to amino acid starvation 229320 229320 'Clrn1' mRNA 1225 1203 1121 22.17 21.45 21.57 1.8 2.19 2.36 21.73 2.116666667 114 136 145 1183 131.6666667 1.51E-147 -3.177337629 GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030140///trans-Golgi network transport vesicle+++GO:0032420///stereocilium+++GO:0045178///basal part of cell GO:0007015///actin filament organization+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0045494///photoreceptor cell maintenance+++GO:0048870///cell motility+++GO:0050885///neuromuscular process controlling balance+++GO:0050896///response to stimulus+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060117///auditory receptor cell development 229323 229323 'Gpr171' mRNA 86 99 92 2.18 2.47 2.47 3.74 2.28 2.61 2.373333333 2.876666667 170 101 115 92.33333333 128.6666667 0.102610948 0.462186542 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0045638///negative regulation of myeloid cell differentiation 229357 229357 'Gpr149' mRNA 9 9 1 0.13 0.12 0.01 0.01 0 0.08 0.086666667 0.03 1 0 6 6.333333333 2.333333333 0.389119635 -1.422099911 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0004930///G protein-coupled receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding GO:0001546///preantral ovarian follicle growth+++GO:0001547///antral ovarian follicle growth+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0060206///estrous cycle phase+++GO:0060280///negative regulation of ovulation 229363 229363 'Gmps' mRNA 1644.94 1563.51 1589.32 14.51 13.79 15.5 16.86 15.54 14.61 14.6 15.67 1982.98 1766.57 1690.54 1599.256667 1813.363333 0.057591596 0.167595872 00230///Purine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003921///GMP synthase activity+++GO:0003922///GMP synthase (glutamine-hydrolyzing) activity+++GO:0005524///ATP binding+++GO:0016462///pyrophosphatase activity+++GO:0016874///ligase activity GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0032263///GMP salvage 229389 229389 'Otol1' mRNA 5334 5353 5034 139.39 137.78 139.56 139.68 138.85 135.57 138.91 138.0333333 6146 5965 5774 5240.333333 5961.666667 0.001799366 0.174634202 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0030198///extracellular matrix organization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0045299///otolith mineralization+++GO:0051260///protein homooligomerization 229445 229445 'Ctso' mRNA 1479 1549 1519 23.21 23.91 25.28 27.42 26.85 28.1 24.13333333 27.45666667 2011 1924 1996 1515.666667 1977 8.10E-07 0.370726891 04142///Lysosome+++04210///Apoptosis GO:0005615///extracellular space+++GO:0005764///lysosome GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0051603///proteolysis involved in cellular protein catabolic process 229473 229473 'Tmem131l' mRNA 361 395 349 3.91 4.18 4.04 4.32 3.94 3.87 4.043333333 4.043333333 463 411 400 368.3333333 424.6666667 0.182637691 0.193825867 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0016055///Wnt signaling pathway+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:0090090///negative regulation of canonical Wnt signaling pathway 229474 229474 'Fhdc1' mRNA 322 299 188 2.88 2.63 1.79 1.52 1.71 1.32 2.433333333 1.516666667 196 216 165 269.6666667 192.3333333 0.022700148 -0.489174236 GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0030030///cell projection organization+++GO:0043149///stress fiber assembly+++GO:0060271///cilium assembly+++GO:0090161///Golgi ribbon formation 229487 229487 'Gatb' mRNA 305 312 330 6.55 6.45 7.18 6.83 6.61 7.55 6.726666667 6.996666667 354 325 379 315.6666667 352.6666667 0.399156757 0.145842429 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0030956///glutamyl-tRNA(Gln) amidotransferase complex "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016884///carbon-nitrogen ligase activity, with glutamine as amido-N-donor+++GO:0050567///glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity" GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0070681///glutaminyl-tRNAGln biosynthesis via transamidation 229488 229488 'Fam160a1' mRNA 1327 1476 1342 16.25 17.78 17.43 9.62 9.94 9.48 17.15333333 9.68 904 913 863 1381.666667 893.3333333 8.89E-14 -0.640262828 GO:0005575///cellular_component GO:0003674///molecular_function GO:1905719///protein localization to perinuclear region of cytoplasm 229499 229499 'Fcrl1' mRNA 0 2 1 0 0.07 0.04 0.68 1.07 0.72 0.036666667 0.823333333 25 37 28 1 30 3.21E-06 4.900659348 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0015026///coreceptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0042113///B cell activation 229503 229503 'Rrnad1' mRNA 625.24 678.06 637.64 13.73 14.42 13.83 8.94 9.65 8.71 13.99333333 9.1 470.62 499.27 453.49 646.98 474.46 6.98E-05 -0.4594051 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 229504 229504 'Isg20l2' mRNA 683.93 648.86 285.01 12.76 11.95 5.66 7.39 9.58 9.36 10.12333333 8.776666667 448.06 569.02 552 539.2666667 523.0266667 0.949663497 -0.033881246 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity "GO:0042254///ribosome biogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 229512 229512 'Smg5' mRNA 2048 2144 2049 23.66 24.41 25.06 17.11 16.3 16.04 24.37666667 16.48333333 1705 1595 1563 2080.333333 1621 3.37E-07 -0.372382073 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm GO:0031625///ubiquitin protein ligase binding+++GO:0042162///telomeric DNA binding+++GO:0042826///histone deacetylase binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070034///telomerase RNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0032204///regulation of telomere maintenance+++GO:0035303///regulation of dephosphorylation" 229517 229517 'Slc25a44' mRNA 1188 1264 1160 18.14 19.08 18.88 16.75 16.43 16.95 18.7 16.71 1261 1205 1232 1204 1232.666667 0.851396872 0.02263967 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0015658///branched-chain amino acid transmembrane transporter activity GO:0006865///amino acid transport+++GO:0009083///branched-chain amino acid catabolic process+++GO:0015803///branched-chain amino acid transport+++GO:0055085///transmembrane transport+++GO:0120161///regulation of cold-induced thermogenesis 229521 229521 'Syt11' mRNA 1821.58 1902.02 1831.81 20.79 21.37 22.24 20.28 21.36 19.17 21.46666667 20.27 2031.64 2094.07 1857.21 1851.803333 1994.306667 0.294590179 0.095251252 GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032009///early phagosome+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0060076///excitatory synapse+++GO:0060077///inhibitory synapse+++GO:0070382///exocytic vesicle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0030276///clathrin binding+++GO:0031369///translation initiation factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding GO:0001778///plasma membrane repair+++GO:0001818///negative regulation of cytokine production+++GO:0006906///vesicle fusion+++GO:0006914///autophagy+++GO:0007612///learning+++GO:0007613///memory+++GO:0009611///response to wounding+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033602///negative regulation of dopamine secretion+++GO:0045806///negative regulation of endocytosis+++GO:0050765///negative regulation of phagocytosis+++GO:0051650///establishment of vesicle localization+++GO:0071277///cellular response to calcium ion+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:1900243///negative regulation of synaptic vesicle endocytosis+++GO:1900424///regulation of defense response to bacterium+++GO:1903979///negative regulation of microglial cell activation+++GO:1905154///negative regulation of membrane invagination+++GO:1905162///regulation of phagosome maturation+++GO:1905171///positive regulation of protein localization to phagocytic vesicle+++GO:1905469///negative regulation of clathrin-coated pit assembly+++GO:1990927///calcium ion regulated lysosome exocytosis 229524 229524 'Msto1' mRNA 609.95 592.24 676.72 19.23 18.4 22.63 24.61 24.38 24.36 20.08666667 24.45 897.04 867.57 859.48 626.3033333 874.6966667 2.71E-05 0.467410236 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003674///molecular_function GO:0007005///mitochondrion organization+++GO:0048311///mitochondrion distribution 229534 229534 'Pbxip1' mRNA 4731 4864 4410 56.22 56.79 55.48 51.49 49.07 49.94 56.16333333 50.16666667 4977 4636 4672 4668.333333 4761.666667 0.82482207 0.017471482 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding" "GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0007155///cell adhesion+++GO:0010467///gene expression+++GO:0016477///cell migration+++GO:0022617///extracellular matrix disassembly+++GO:0030154///cell differentiation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061975///articular cartilage development+++GO:0097043///histone H3-K56 acetylation+++GO:1901148///gene expression involved in extracellular matrix organization+++GO:1902732///positive regulation of chondrocyte proliferation+++GO:2001106///regulation of Rho guanyl-nucleotide exchange factor activity" 229541 229541 'Dennd4b' mRNA 479 528 481 4.88 5.1 5.41 5.61 5.25 4.81 5.13 5.223333333 647 601 543 496 597 0.040678367 0.255460848 GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity GO:0032483///regulation of Rab protein signal transduction+++GO:0050790///regulation of catalytic activity 229542 229542 'Gatad2b' mRNA 613.01 593.05 498.73 4.26 4.01 3.68 4.38 3.3 4.59 3.983333333 4.09 729.11 538 744.62 568.2633333 670.5766667 0.113219416 0.228596428 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016581///NuRD complex+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated" 229543 229543 'Ints3' mRNA 911 910 849 11.02 10.83 10.91 8.59 9.44 9.16 10.92 9.063333333 819 877 844 890 846.6666667 0.475192716 -0.082269439 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032039///integrator complex+++GO:0035861///site of double-strand break+++GO:0070876///SOSS complex GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0016180///snRNA processing+++GO:0044818///mitotic G2/M transition checkpoint 229584 229584 'Pogz' mRNA 895 840 818 7.21 6.65 6.97 4.99 4.71 5.15 6.943333333 4.95 714 658 709 851 693.6666667 0.002346499 -0.306738716 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0051382///kinetochore assembly 229588 229588 'Gm128' mRNA 13.18 13.34 9.25 0.53 0.53 0.39 1.04 0.76 0.83 0.483333333 0.876666667 29.7 21 23 11.92333333 24.56666667 0.093005989 1.051750614 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0042127///regulation of cell proliferation 229589 229589 'Prune1' mRNA 796.43 893.61 747.58 12.85 14.51 13.26 10.2 10.96 9.13 13.54 10.09666667 748.95 756.95 632.98 812.54 712.96 0.092324595 -0.199138347 00230///Purine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0004309///exopolyphosphatase activity+++GO:0004427///inorganic diphosphatase activity+++GO:0015631///tubulin binding+++GO:0016462///pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0006798///polyphosphate catabolic process+++GO:0016311///dephosphorylation+++GO:0031113///regulation of microtubule polymerization+++GO:0050767///regulation of neurogenesis 229593 229593 'Golph3l' mRNA 975 1023 988 18.96 19.63 20.36 18.9 19.26 18.61 19.65 18.92333333 1113 1111 1057 995.3333333 1093.666667 0.214405656 0.123874522 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031985///Golgi cisterna+++GO:0032580///Golgi cisterna membrane GO:0008289///lipid binding+++GO:0070273///phosphatidylinositol-4-phosphate binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0048194///Golgi vesicle budding+++GO:0050714///positive regulation of protein secretion" 229595 229595 'Adamtsl4' mRNA 232 246 233 3.17 3.29 3.36 10.72 11.8 9.9 3.273333333 10.80666667 901 973 805 237 893 1.19E-54 1.902835169 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0004222///metalloendopeptidase activity+++GO:0042802///identical protein binding GO:0002064///epithelial cell development+++GO:0006915///apoptotic process+++GO:0030198///extracellular matrix organization+++GO:0043065///positive regulation of apoptotic process 229599 229599 'Ciart' mRNA 305 370 360 11.56 13.48 14.24 5.8 7.71 6.82 13.09333333 6.776666667 183 227 201 345 203.6666667 5.81E-06 -0.772096751 GO:0005634///nucleus+++GO:0016605///PML body GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0070888///E-box binding "GO:0032922///circadian regulation of gene expression+++GO:0045475///locomotor rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 229600 229600 'BC028528' mRNA 227.45 192.75 191.43 16 14.57 14.63 61.79 63.41 59.39 15.06666667 61.53 887.26 874.32 827.75 203.8766667 863.11 2.16E-66 2.073984424 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 229603 229603 'Otud7b' mRNA 1635 1588 1559.99 10.68 10.2 10.87 7.85 6.48 7.3 10.58333333 7.21 1377 1123 1247 1594.33 1249 2.78E-05 -0.365395859 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:1990380///Lys48-specific deubiquitinase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002385///mucosal immune response+++GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0032717///negative regulation of interleukin-8 production+++GO:0035871///protein K11-linked deubiquitination+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:1900181///negative regulation of protein localization to nucleus 229615 229615 'Pias3' mRNA 1138.63 1036.74 1069 23.17 21.31 23.41 18.08 18.72 17.18 22.63 17.99333333 999 1002 933 1081.456667 978 0.124261828 -0.156862145 04120///Ubiquitin mediated proteolysis+++04630///JAK-STAT signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0045202///synapse GO:0001085///RNA polymerase II transcription factor binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0015459///potassium channel regulator activity+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0061665///SUMO ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009725///response to hormone+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016925///protein sumoylation+++GO:0033234///negative regulation of protein sumoylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045838///positive regulation of membrane potential+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071847///TNFSF11-mediated signaling pathway" 229644 229644 'Trim45' mRNA 368 369 259 4.34 4.42 3.31 0.91 1 1.21 4.023333333 1.04 91 89 110 332 96.66666667 1.29E-20 -1.784643556 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060348///bone development" 229658 229658 'Vangl1' mRNA 1129.03 997 968 11.62 9.76 10.27 8.5 9.5 9.06 10.55 9.02 997 1056 1006 1031.343333 1019.666667 0.849874678 -0.026626209 04310///Wnt signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0043473///pigmentation 229663 229663 'Csde1' mRNA 6602 7087 6892 85.95 90.63 95.3 81.02 73.15 76.32 90.62666667 76.83 7156 6313 6524 6860.333333 6664.333333 0.474552338 -0.05563881 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070937///CRD-mediated mRNA stability complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0035613///RNA stem-loop binding "GO:0034063///stress granule assembly+++GO:0070966///nuclear-transcribed mRNA catabolic process, no-go decay+++GO:0075522///IRES-dependent viral translational initiation" 229672 229672 'Bcl2l15' mRNA 253.47 265.4 221.08 3.9 3.91 3.66 3.96 5.99 5.81 3.823333333 5.253333333 266.24 304.41 287.99 246.65 286.2133333 0.251790402 0.20588771 GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process+++GO:0042981///regulation of apoptotic process 229675 229675 'Rsbn1' mRNA 871 905 876 9.46 9.32 9.77 5.79 5.89 6.33 9.516666667 6.003333333 662 589 657 884 636 1.16E-06 -0.487783569 GO:0005634///nucleus GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0006325///chromatin organization+++GO:0008150///biological_process 229681 229681 'St7l' mRNA 712 764 794 6.66 7.06 7.9 5 5.07 5.51 7.206666667 5.193333333 611 607 650 756.6666667 622.6666667 0.011030097 -0.294975503 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0030308///negative regulation of cell growth 229687 229687 'Chil5' mRNA 35 43 33 1.34 1.24 1.09 0.01 0.17 0.1 1.223333333 0.093333333 1 6 3 37 3.333333333 7.28E-07 -3.475434475 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0008061///chitin binding+++GO:0019900///kinase binding GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0032722///positive regulation of chemokine production 229688 229688 'Chil6' mRNA 1 3 2 0.03 0.1 0.07 0.03 0 0 0.066666667 0.01 1 0 0 2 0.333333333 0.377275234 -2.490402891 00520///Amino sugar and nucleotide sugar metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004568///chitinase activity+++GO:0008061///chitin binding+++GO:0019900///kinase binding GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0032722///positive regulation of chemokine production 229697 229697 'Cym' mRNA 13 1 0 0.64 0.05 0 0 0.09 0.18 0.23 0.09 0 2 4 4.666666667 2 0.575257941 -1.196489711 GO:0005575///cellular_component GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 229699 229699 'Slc16a4' mRNA 127 161 143 3.29 4.07 3.85 3.8 3.48 3.2 3.736666667 3.493333333 171 155 140 143.6666667 155.3333333 0.726099345 0.100113806 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport 229700 229700 'Rbm15' mRNA 147 107 110 2.46 1.76 1.95 2.45 2.51 2.29 2.056666667 2.416666667 169 169 153 121.3333333 163.6666667 0.072403764 0.421356448 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001510///RNA methylation+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0048536///spleen development+++GO:0060412///ventricular septum morphogenesis+++GO:0060674///placenta blood vessel development" 229706 229706 'Slc6a17' mRNA 316 352 197 2.7 2.93 1.79 1.89 1.89 1.86 2.473333333 1.88 248 248 243 288.3333333 246.3333333 0.295710168 -0.228168997 GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031224///intrinsic component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0015293///symporter activity GO:0006836///neurotransmitter transport+++GO:0007420///brain development+++GO:0015804///neutral amino acid transport+++GO:0015816///glycine transport+++GO:0015820///leucine transport+++GO:0015824///proline transport+++GO:0032328///alanine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport 229707 229707 'Strip1' mRNA 1175 1319 1204 19.88 21.95 21.6 20.87 20.68 20.21 21.14333333 20.58666667 1420 1374 1331 1232.666667 1375 0.108980531 0.146045384 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis+++GO:0030866///cortical actin cytoskeleton organization 229709 229709 'Ahcyl1' mRNA 1277 1382 1312 18.1 19.36 19.89 25.21 24.25 25.49 19.11666667 24.98333333 2026 1888 1989 1323.666667 1967.666667 1.13E-13 0.559582374 00270///Cysteine and methionine metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044233///Mitochondria-associated ER Membrane GO:0003723///RNA binding+++GO:0004013///adenosylhomocysteinase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006378///mRNA polyadenylation+++GO:0006611///protein export from nucleus+++GO:0006730///one-carbon metabolic process+++GO:0006915///apoptotic process+++GO:0010765///positive regulation of sodium ion transport+++GO:0031440///regulation of mRNA 3'-end processing+++GO:0032412///regulation of ion transmembrane transporter activity+++GO:0033353///S-adenosylmethionine cycle+++GO:0038166///angiotensin-activated signaling pathway+++GO:0042045///epithelial fluid transport+++GO:0044070///regulation of anion transport+++GO:0051592///response to calcium ion+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering 229714 229714 'Gpr61' mRNA 10 11 15 0.18 0.19 0.29 0 0.03 0.03 0.22 0.02 0 2 2 12 1.333333333 0.007947578 -3.184336255 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:1990763///arrestin family protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043950///positive regulation of cAMP-mediated signaling 229715 229715 'Amigo1' mRNA 666 757 550 6.36 7.1 5.6 2.48 2.71 2.39 6.353333333 2.526666667 290 319 275 657.6666667 294.6666667 1.59E-18 -1.163978639 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:1990030///pericellular basket GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007413///axonal fasciculation+++GO:0007420///brain development+++GO:0010976///positive regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0042552///myelination+++GO:0050772///positive regulation of axonogenesis+++GO:0051965///positive regulation of synapse assembly+++GO:0106030///neuron projection fasciculation+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity+++GO:1905232///cellular response to L-glutamate 229722 229722 'Elapor1' mRNA 85 87 97 0.77 0.78 0.92 0.26 0.43 0.31 0.823333333 0.333333333 33 55 38 89.66666667 42 8.87E-04 -1.105852145 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0044090///positive regulation of vacuole organization+++GO:2000786///positive regulation of autophagosome assembly 229725 229725 'Clcc1' mRNA 1507.76 1558.39 1579.83 39.26 40 43.54 29.47 30.03 28.03 40.93333333 29.17666667 1295.81 1284.01 1192.96 1548.66 1257.593333 2.93E-04 -0.313700652 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0034707///chloride channel complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044233///Mitochondria-associated ER Membrane GO:0005254///chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport 229731 229731 'Slc25a24' mRNA 176 183 200 2.84 2.9 3.42 8.59 9.21 8.98 3.053333333 8.926666667 614 643 621 186.3333333 626 1.00E-37 1.734958519 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0006839///mitochondrial transport+++GO:0010941///regulation of cell death+++GO:0015867///ATP transport+++GO:0034599///cellular response to oxidative stress+++GO:0055085///transmembrane transport+++GO:0071277///cellular response to calcium ion 229759 229759 'Olfm3' mRNA 9 12 12 0.1 0.14 0.16 0 0 0 0.133333333 0 0 0 0 11 0 2.19E-04 -5.917079315 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse GO:0005515///protein binding GO:0042462///eye photoreceptor cell development 229776 229776 'Cdc14a' mRNA 2923 3101 2911 35.07 36.68 37.34 10.85 10.82 10.52 36.36333333 10.73 1039 1006 976 2978.333333 1007 4.46E-112 -1.576313489 04110///Cell cycle GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0060091///kinocilium+++GO:0072686///mitotic spindle+++GO:1902636///kinociliary basal body GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0007096///regulation of exit from mitosis+++GO:0007605///sensory perception of sound+++GO:0016311///dephosphorylation+++GO:0032467///positive regulation of cytokinesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0071850///mitotic cell cycle arrest 229780 229780 'Trmt13' mRNA 378.76 383.11 360.72 5.88 5.7 5.56 4.86 4.6 4.6 5.713333333 4.686666667 326.27 281.44 287.89 374.1966667 298.5333333 0.020004943 -0.338772057 GO:0005575///cellular_component GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0106050///tRNA 2'-O-methyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 229782 229782 'Slc35a3' mRNA 657 738.81 378 7.83 9.35 4.12 4.72 4.86 5.3 7.1 4.96 525 492.45 561 591.27 526.15 0.415677696 -0.167016989 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0005459///UDP-galactose transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:1990569///UDP-N-acetylglucosamine transmembrane transport 229791 229791 'Plppr4' mRNA 955.28 995 891 8.92 9.14 8.83 1.4 1.56 1.87 8.963333333 1.61 172 188 223 947.0933333 194.3333333 3.36E-77 -2.294311596 GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042577///lipid phosphatase activity+++GO:0052642///lysophosphatidic acid phosphatase activity GO:0006644///phospholipid metabolic process+++GO:0007165///signal transduction+++GO:0007409///axonogenesis+++GO:0046839///phospholipid dephosphorylation+++GO:0048839///inner ear development 229801 229801 'Tram1l1' mRNA 47 51 46 1.19 1.27 1.24 0.92 0.5 0.73 1.233333333 0.716666667 42 22 32 48 32 0.176197894 -0.600261641 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003674///molecular_function "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0015031///protein transport+++GO:0045048///protein insertion into ER membrane" 229841 229841 'Cenpe' mRNA 28 34 33 0.19 0.23 0.24 2.02 2.34 2.1 0.22 2.153333333 346 391 347 31.66666667 361.3333333 5.56E-56 3.501663362 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005828///kinetochore microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:1990023///mitotic spindle midzone" "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0019901///protein kinase binding+++GO:0043515///kinetochore binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0000278///mitotic cell cycle+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0007059///chromosome segregation+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007080///mitotic metaphase plate congression+++GO:0007088///regulation of mitotic nuclear division+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007275///multicellular organism development+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031647///regulation of protein stability+++GO:0045184///establishment of protein localization+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0045860///positive regulation of protein kinase activity+++GO:0050793///regulation of developmental process+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051382///kinetochore assembly+++GO:0051984///positive regulation of chromosome segregation+++GO:0051987///positive regulation of attachment of spindle microtubules to kinetochore+++GO:0099606///microtubule plus-end directed mitotic chromosome migration+++GO:0099607///lateral attachment of mitotic spindle microtubules to kinetochore 229877 229877 'Rap1gds1' mRNA 919 951 735 13.79 14.29 12.05 16.71 16.88 18.62 13.37666667 17.40333333 1269 1244 1366 868.3333333 1293 3.16E-09 0.567343764 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0014829///vascular smooth muscle contraction+++GO:0031034///myosin filament assembly+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0043547///positive regulation of GTPase activity+++GO:0051561///positive regulation of mitochondrial calcium ion concentration 229898 229898 'Gbp5' mRNA 48 42 52 0.87 0.75 1 2.18 1.57 2.32 0.873333333 2.023333333 138 97 142 47.33333333 125.6666667 1.35E-06 1.391429071 04621///NOD-like receptor signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0009617///response to bacterium+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032741///positive regulation of interleukin-18 production+++GO:0034067///protein localization to Golgi apparatus+++GO:0045089///positive regulation of innate immune response+++GO:0051289///protein homotetramerization+++GO:0071346///cellular response to interferon-gamma+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly 229900 229900 'Gbp7' mRNA 1147.3 1274.11 1312.25 10.89 11.89 13.21 17.62 16.73 16.85 11.99666667 17.06666667 2137.84 1982.9 1979.58 1244.553333 2033.44 1.00E-15 0.693263852 04621///NOD-like receptor signaling pathway GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071346///cellular response to interferon-gamma 229905 229905 'Kyat3' mRNA 168 157 156 4.78 4.33 4.51 5.01 4.54 5.23 4.54 4.926666667 207 177 200 160.3333333 194.6666667 0.200754828 0.267267097 00270///Cysteine and methionine metabolism+++00380///Tryptophan metabolism+++00450///Selenocompound metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0036137///kynurenine aminotransferase activity+++GO:0042803///protein homodimerization activity+++GO:0047315///kynurenine-glyoxylate transaminase activity+++GO:0047804///cysteine-S-conjugate beta-lyase activity GO:0006103///2-oxoglutarate metabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0009058///biosynthetic process+++GO:0070189///kynurenine metabolic process+++GO:0097052///L-kynurenine metabolic process+++GO:0097053///L-kynurenine catabolic process 229906 229906 'Gtf2b' mRNA 1026 1023 902 49.88 49.1 46.52 48.66 46.76 48.17 48.5 47.86333333 1149 1077 1100 983.6666667 1108.666667 0.078509262 0.162413343 03022///Basal transcription factors+++05017///Spinocerebellar ataxia+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0032993///protein-DNA complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0097550///transcriptional preinitiation complex "GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0003677///DNA binding+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0017025///TBP-class protein binding+++GO:0046872///metal ion binding+++GO:0046966///thyroid hormone receptor binding+++GO:1990841///promoter-specific chromatin binding" "GO:0001174///transcriptional start site selection at RNA polymerase II promoter+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006473///protein acetylation+++GO:0016573///histone acetylation+++GO:0019083///viral transcription+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0070897///transcription preinitiation complex assembly+++GO:1904798///positive regulation of core promoter binding+++GO:1990114///RNA polymerase II core complex assembly" 229927 229927 'Clca3b' mRNA 1 0 2 0.02 0 0.04 0 0.03 0 0.02 0.01 0 2 0 1 0.666666667 0.866964852 -0.613114947 04924///Renin secretion+++04972///Pancreatic secretion GO:0005887///integral component of plasma membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006821///chloride transport 229933 229933 'Clca2' mRNA 102 110 117 1.42 1.44 1.66 1.24 1.23 0.93 1.506666667 1.133333333 107 103 76 109.6666667 95.33333333 0.485032646 -0.217184062 04924///Renin secretion+++04972///Pancreatic secretion GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031965///nuclear membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0015276///ligand-gated ion channel activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007155///cell adhesion 229937 229937 'Znhit6' mRNA 875 943 844 21.41 23.7 23.8 35.5 36.79 35.6 22.97 35.96333333 1649 1592 1539 887.3333333 1593.333333 1.46E-25 0.833615298 GO:0005634///nucleus+++GO:0070761///pre-snoRNP complex GO:0001094///TFIID-class transcription factor complex binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000492///box C/D snoRNP assembly+++GO:0042254///ribosome biogenesis+++GO:0048254///snoRNA localization+++GO:0051259///protein complex oligomerization" 229949 229949 'Ak5' mRNA 133 100 75 2.18 1.7 1.31 1.17 1.48 1.41 1.73 1.353333333 82 95 94 102.6666667 90.33333333 0.589519909 -0.187829451 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019205///nucleobase-containing compound kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046034///ATP metabolic process+++GO:0046940///nucleoside monophosphate phosphorylation 230027 230027 'Coq3' mRNA 415.22 419.94 463.09 7 6.99 8.34 6.7 8.6 6.15 7.443333333 7.15 433.89 511.77 382.38 432.75 442.68 0.927779591 0.018202375 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane "GO:0004395///hexaprenyldihydroxybenzoate methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0008425///2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity+++GO:0008689///3-demethylubiquinone-9 3-O-methyltransferase activity+++GO:0010420///polyprenyldihydroxybenzoate methyltransferase activity+++GO:0016740///transferase activity+++GO:0061542///3-demethylubiquinone-n 3-O-methyltransferase activity" GO:0006071///glycerol metabolic process+++GO:0006744///ubiquinone biosynthetic process+++GO:0010795///regulation of ubiquinone biosynthetic process+++GO:0032259///methylation 230073 230073 'Ddx58' mRNA 1023 1035 1126 11.09 11.05 12.92 21.01 20.3 20.4 11.68666667 20.57 2233 2108 2098 1061.333333 2146.333333 1.79E-32 1.001072522 04064///NF-kappa B signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0009597///detection of virus+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0030334///regulation of cell migration+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0039529///RIG-I signaling pathway+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051607///defense response to virus+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0071360///cellular response to exogenous dsRNA 230075 230075 'Ndufb6' mRNA 1592 1626 1604 176.96 179.65 189.23 203.77 236.02 213.72 181.9466667 217.8366667 2094 2359 2118 1607.333333 2190.333333 1.66E-07 0.435200665 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0042775///mitochondrial ATP synthesis coupled electron transport" 230082 230082 'Nol6' mRNA 857 963 853 10.26 11.34 10.83 11.16 10.22 10.08 10.81 10.48666667 1073 960 939 891 990.6666667 0.181983828 0.141287636 03008///Ribosome biogenesis in eukaryotes GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005916///fascia adherens+++GO:0005927///muscle tendon junction+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0032040///small-subunit processome+++GO:0032545///CURI complex+++GO:0034456///UTP-C complex GO:0003723///RNA binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017166///vinculin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051371///muscle alpha-actinin binding GO:0006364///rRNA processing+++GO:0006409///tRNA export from nucleus+++GO:0030036///actin cytoskeleton organization+++GO:0071691///cardiac muscle thin filament assembly 230085 230085 'Phf24' mRNA 24.05 23.75 13.77 0.12 0.12 0.08 0.12 0.1 0.06 0.106666667 0.093333333 25.34 18.83 13.9 20.52333333 19.35666667 0.886854997 -0.104765438 GO:0005575///cellular_component GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain" 230088 230088 'Fam214b' mRNA 459 530 420 8.24 9.29 8.05 12.13 10.95 10.46 8.526666667 11.18 777 686 652 469.6666667 705 9.50E-07 0.576180084 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 230098 230098 'Arhgef39' mRNA 6 7 6 0.16 0.16 0.15 1.62 2.28 1.95 0.156666667 1.95 77 107 90.36 6.333333333 91.45333333 2.44E-16 3.842635258 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity GO:0030335///positive regulation of cell migration+++GO:0050790///regulation of catalytic activity 230099 230099 'Car9' mRNA 9 9 14 0.27 0.26 0.43 2.53 2.62 2.44 0.32 2.53 100 101 91.64 10.66666667 97.54666667 2.06E-15 3.173600796 00910///Nitrogen metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0002009///morphogenesis of an epithelium+++GO:0006730///one-carbon metabolic process+++GO:0033574///response to testosterone+++GO:0042493///response to drug+++GO:0046903///secretion 230101 230101 'Gba2' mRNA 653.16 703 385 10.04 10.63 6.28 5.57 5.77 6.59 8.983333333 5.976666667 417.14 422 478 580.3866667 439.0466667 0.024023217 -0.401970713 00511///Other glycan degradation+++00600///Sphingolipid metabolism GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0090498///extrinsic component of Golgi membrane "GO:0004348///glucosylceramidase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008422///beta-glucosidase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046527///glucosyltransferase activity+++GO:0050295///steryl-beta-glucosidase activity" GO:0005975///carbohydrate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006680///glucosylceramide catabolic process+++GO:0007417///central nervous system development+++GO:0008152///metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008206///bile acid metabolic process+++GO:0016139///glycoside catabolic process+++GO:0021954///central nervous system neuron development+++GO:0030259///lipid glycosylation+++GO:0030833///regulation of actin filament polymerization+++GO:0031113///regulation of microtubule polymerization+++GO:0097035///regulation of membrane lipid distribution 230103 230103 'Npr2' mRNA 451 475 441 7.52 7.68 7.81 6.78 6.54 6.3 7.67 6.54 452 428 412 455.6666667 430.6666667 0.538940319 -0.093062728 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04921///Oxytocin signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0016941///natriuretic peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0042562///hormone binding+++GO:0042802///identical protein binding GO:0001503///ossification+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0022414///reproductive process+++GO:0035556///intracellular signal transduction+++GO:0051447///negative regulation of meiotic cell cycle+++GO:0060348///bone development+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:1900194///negative regulation of oocyte maturation 230119 230119 'Zbtb5' mRNA 596 680 616 6.61 7.35 7.47 5.63 5.1 5.41 7.143333333 5.38 581 515 540 630.6666667 545.3333333 0.06543479 -0.221908594 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 230125 230125 'Slc25a51' mRNA 1768.07 1810.38 1537.56 21.37 21.53 19.72 19.29 18.41 18.54 20.87333333 18.74666667 1835.69 1710.82 1708.48 1705.336667 1751.663333 0.777776881 0.02878681 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0051724///NAD transmembrane transporter activity GO:0019646///aerobic electron transport chain+++GO:0035352///NAD transmembrane transport+++GO:1990549///mitochondrial NAD transmembrane transport 230126 230126 'Shb' mRNA 47 45 40 0.95 0.89 0.86 1.61 1.63 1.37 0.9 1.536666667 92 91 76 44 86.33333333 0.002124724 0.962310016 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0042100///B cell proliferation+++GO:0045624///positive regulation of T-helper cell differentiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0048514///blood vessel morphogenesis+++GO:0050852///T cell receptor signaling pathway+++GO:0071425///hematopoietic stem cell proliferation+++GO:1900194///negative regulation of oocyte maturation 230145 230145 'Galnt12' mRNA 16 19 8 0.4 0.47 0.21 0.52 0.47 0.58 0.36 0.523333333 24 21 26 14.33333333 23.66666667 0.268711504 0.723698929 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008150///biological_process 230157 230157 'Tmeff1' mRNA 58 58 37 1.29 1.25 0.89 1.2 0.75 1.05 1.143333333 1 61 40 52 51 51 0.995813519 -0.006842104 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007275///multicellular organism development+++GO:0007528///neuromuscular junction development+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0043113///receptor clustering 230161 230161 'Acnat1' mRNA 18.52 8.06 5.6 0.17 0.08 0.06 0.03 0.08 0.08 0.103333333 0.063333333 3.38 8.6 8.12 10.72666667 6.7 0.530861574 -0.697949905 00120///Primary bile acid biosynthesis+++00430///Taurine and hypotaurine metabolism+++01040///Biosynthesis of unsaturated fatty acids+++04146///Peroxisome+++04976///Bile secretion GO:0005777///peroxisome "GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process 230162 230162 'Zfp189' mRNA 149 185 168 2.7 3.3 3.21 2.8 3.11 2.75 3.07 2.886666667 177 194 170 167.3333333 180.3333333 0.71428263 0.096763093 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 230233 230233 'Elp1' mRNA 937.79 988.67 884.53 7.94 8.24 7.91 6.64 5.79 5.6 8.03 6.01 923.15 788.79 756.8 936.9966667 822.9133333 0.062259519 -0.199226862 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033588///Elongator holoenzyme complex GO:0000049///tRNA binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0002098///tRNA wobble uridine modification+++GO:0002926///tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation+++GO:0007252///I-kappaB phosphorylation+++GO:0008033///tRNA processing 230234 230234 'Abitram' mRNA 485 514 465 6.42 6.59 6.44 5.43 4.73 4.69 6.483333333 4.95 499.15 406 408 488 437.7166667 0.237599867 -0.169557145 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0051015///actin filament binding GO:0030833///regulation of actin filament polymerization+++GO:0048813///dendrite morphogenesis+++GO:0051489///regulation of filopodium assembly 230235 230235 'Frrs1l' mRNA 32 46 40 0.45 0.63 0.6 0.18 0.12 0.2 0.56 0.166666667 15 10 16 39.33333333 13.66666667 0.002525881 -1.538903905 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0003674///molecular_function GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:1900449///regulation of glutamate receptor signaling pathway 230249 230249 'Ecpas' mRNA 1483 1422 1323 8.9 8.34 8.42 7.88 6.56 7.94 8.553333333 7.46 1509 1231 1472 1409.333333 1404 0.879627135 -0.017458516 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle GO:0060090///molecular adaptor activity+++GO:0070628///proteasome binding GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043248///proteasome assembly 230257 230257 'Ptbp3' mRNA 1495 1369 1143 11.51 10.37 9.34 19.33 16.13 18.65 10.40666667 18.03666667 2872 2343 2691 1335.666667 2635.333333 4.08E-28 0.971012914 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0033119///negative regulation of RNA splicing+++GO:0043249///erythrocyte maturation+++GO:0043484///regulation of RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 230259 230259 'E130308A19Rik' mRNA 1773 1842 1070 19.55 19.39 9.69 7.6 8.91 8.98 16.21 8.496666667 990 972 1062 1561.666667 1008 3.52E-06 -0.631764664 GO:0008150///biological_process 230279 230279 'Tmem268' mRNA 349 348 366 4.37 4.32 5.02 7.72 7.44 6.93 4.57 7.363333333 641 602 555 354.3333333 599.3333333 1.86E-09 0.744314556 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 230316 230316 'Megf9' mRNA 1791 1840 1471 32.08 32.44 27.95 20.77 21.77 21.61 30.82333333 21.38333333 1334 1366 1344 1700.666667 1348 4.67E-05 -0.342641365 GO:0005604///basement membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading 230376 230376 'Haus6' mRNA 176 191 190 1.85 1.83 2.26 2.35 2.21 2.04 1.98 2.2 246 238 213 185.6666667 232.3333333 0.104061971 0.310303859 GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0034451///centriolar satellite+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly 230379 230379 'Acer2' mRNA 667.58 677.79 708.05 12.84 11.89 13.07 10.95 11.69 10.62 12.6 11.08666667 768.9 839.77 744.15 684.4733333 784.2733333 0.128513581 0.183401941 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0046872///metal ion binding+++GO:0071633///dihydroceramidase activity+++GO:0102121///ceramidase activity" "GO:0001953///negative regulation of cell-matrix adhesion+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0010506///regulation of autophagy+++GO:0010942///positive regulation of cell death+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0032526///response to retinoic acid+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0035690///cellular response to drug+++GO:0042981///regulation of apoptotic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046514///ceramide catabolic process+++GO:0090285///negative regulation of protein glycosylation in Golgi" 230393 230393 'Focad' mRNA 347.68 388.8 320.31 3.08 3.33 2.92 2.32 2.32 2.25 3.11 2.296666667 305.91 299.49 287.3 352.2633333 297.5666667 0.099230992 -0.253088455 GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function GO:0008150///biological_process 230459 230459 'Cyp2j13' mRNA 3 1 3 0.04 0.01 0.04 0.03 0.01 0.01 0.03 0.016666667 3 1 1 2.333333333 1.666666667 0.828592257 -0.518168832 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 230484 230484 'Usp1' mRNA 419 469 210 6.42 7.09 3.48 5.5 4.45 6.45 5.663333333 5.466666667 406 321 459 366 395.3333333 0.692383976 0.113650548 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001501///skeletal system development+++GO:0006281///DNA repair+++GO:0006282///regulation of DNA repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0016579///protein deubiquitination+++GO:0035520///monoubiquitinated protein deubiquitination 230500 230500 'Efcab7' mRNA 222 225 218 5.62 5.6 5.8 3.32 3.49 3.25 5.673333333 3.353333333 146 150 138 221.6666667 144.6666667 7.54E-04 -0.627325995 04340///Hedgehog signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0098797///plasma membrane protein complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0042307///positive regulation of protein import into nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903569///positive regulation of protein localization to ciliary membrane 230514 230514 'Leprot' mRNA 1945 2045 2103 61.14 63.29 69.96 92.54 86.82 92.64 64.79666667 90.66666667 3388 3096 3281 2031 3255 9.21E-20 0.666127866 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0060400///negative regulation of growth hormone receptor signaling pathway+++GO:2000009///negative regulation of protein localization to cell surface 230576 230576 'Ttc22' mRNA 80 99 75 2.09 2.59 2.14 1.6 1.48 1.94 2.273333333 1.673333333 73 72 88 84.66666667 77.66666667 0.725919533 -0.132302759 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 230577 230577 'Pars2' mRNA 198 199 166 4.72 4.76 4.19 3.28 3.5 3.79 4.556666667 3.523333333 158 161 182 187.6666667 167 0.435257739 -0.176559852 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004827///proline-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006433///prolyl-tRNA aminoacylation 230579 230579 'Fam151a' mRNA 0 1.61 0 0 0.05 0 0.04 0 0 0.016666667 0.013333333 1.47 0 0 0.536666667 0.49 0.998591786 -0.011756601 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 230582 230582 'Cyb5rl' mRNA 186 196 176 3.76 3.86 3.73 3.57 4.15 3.85 3.783333333 3.856666667 177 196 194 186 189 0.958547891 0.013513942 00520///Amino sugar and nucleotide sugar metabolism GO:0005654///nucleoplasm "GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0016491///oxidoreductase activity" 230584 230584 'Yipf1' mRNA 914 981 915 41.76 44.28 44.38 45.58 50.32 48.61 43.47333333 48.17 1146 1234 1177 936.6666667 1185.666667 3.48E-04 0.329372694 GO:0000138///Golgi trans cisterna+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031902///late endosome membrane GO:0031267///small GTPase binding GO:0016192///vesicle-mediated transport 230587 230587 'Glis1' mRNA 178 132 121 3.51 2.62 2.54 0.29 0.31 0.3 2.89 0.3 17 18 17 143.6666667 17.33333333 9.91E-21 -3.05895421 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010454///negative regulation of cell fate commitment+++GO:0030154///cell differentiation+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 230590 230590 'Zyg11a' mRNA 2 1 1 0.03 0.01 0.02 0 0.01 0 0.02 0.003333333 0 1 0 1.333333333 0.333333333 0.574922392 -1.902275385 GO:0031462///Cul2-RING ubiquitin ligase complex 230594 230594 'Tut4' mRNA 674.32 701.25 665.24 5.78 5.96 6.14 4.5 3.83 4.26 5.96 4.196666667 594.52 498.54 546.83 680.27 546.63 0.003625516 -0.329520491 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0050265///RNA uridylyltransferase activity+++GO:0070569///uridylyltransferase activity "GO:0001556///oocyte maturation+++GO:0001816///cytokine production+++GO:0010526///negative regulation of transposition, RNA-mediated+++GO:0010586///miRNA metabolic process+++GO:0010587///miRNA catabolic process+++GO:0019827///stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0071044///histone mRNA catabolic process+++GO:0071076///RNA 3' uridylation+++GO:1990074///polyuridylation-dependent mRNA catabolic process" 230596 230596 'Prpf38a' mRNA 738 817 777 28.65 31.29 32.01 28.29 27.78 29.1 30.65 28.39 837 802 833 777.3333333 824 0.56368142 0.071800626 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 230597 230597 'Zfyve9' mRNA 1122.95 1054 999.31 7.35 6.77 6.8 4.24 4.13 4.25 6.973333333 4.206666667 782.58 743.47 770.13 1058.753333 765.3933333 1.25E-07 -0.479323988 04144///Endocytosis+++04350///TGF-beta signaling pathway GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0019904///protein domain specific binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016197///endosomal transport+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway 230598 230598 'Nrd1' mRNA 2566.78 2484.24 2487.04 32 30.41 32.81 30.78 29.5 31.84 31.74 30.70666667 2849.14 2664.9 2853.04 2512.686667 2789.026667 0.058721195 0.13784962 GO:0005739///mitochondrion GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0052548///regulation of endopeptidase activity+++GO:0120163///negative regulation of cold-induced thermogenesis 230603 230603 'Ttc39a' mRNA 47 47 50 1.13 1.11 1.29 3.79 4.49 3.84 1.176666667 4.04 178 206 176 48 186.6666667 6.11E-16 1.947775514 GO:0005813///centrosome GO:0003674///molecular_function GO:0008150///biological_process 230612 230612 'Slc5a9' mRNA 1 0 0 0.01 0 0 0.08 0 0.01 0.003333333 0.03 4 0 1 0.333333333 1.666666667 0.519353894 2.183811756 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005412///glucose:sodium symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 230648 230648 'Efcab14' mRNA 2264.04 2293.16 2408.93 25.63 25.82 28.96 22.37 21.5 22.55 26.80333333 22.14 2258.91 2166.21 2171.63 2322.043333 2198.916667 0.293668852 -0.092956273 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 230649 230649 'Atpaf1' mRNA 493 507 398 15.96 16.32 13.95 12.88 13.49 12.18 15.41 12.85 448 462 415 466 441.6666667 0.604570125 -0.084760571 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0065003///protein-containing complex assembly 230654 230654 'Lrrc41' mRNA 1678.44 1788.94 1705.99 30.02 31.22 32.15 34.01 36.51 34.18 31.13 34.9 2187.43 2291.45 2122.32 1724.456667 2200.4 8.38E-06 0.340512314 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination 230657 230657 'Tmem69' mRNA 410.17 318.12 388.88 11.77 7.98 10.53 9.43 11.42 11.21 10.09333333 10.68666667 450.76 507.86 476.57 372.39 478.3966667 0.024198854 0.347262265 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 230661 230661 'Tesk2' mRNA 2064.41 2120.31 2060.24 37.39 37.79 39.58 17.53 16.81 19.01 38.25333333 17.78333333 1115.12 1041.66 1166.91 2081.653333 1107.896667 7.59E-33 -0.922844112 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0048041///focal adhesion assembly 230673 230673 'Ipo13' mRNA 3848 4129 4320 58.36 61.63 69.54 28.82 28.88 26.92 63.17666667 28.20666667 2185 2136 1977 4099 2099.333333 7.52E-36 -0.980199191 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0031267///small GTPase binding+++GO:0035259///glucocorticoid receptor binding GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport 230674 230674 'Kdm4a' mRNA 916 1002 816 13.98 14.97 13.55 9.46 9.63 10.43 14.16666667 9.84 706 702 749 911.3333333 719 5.25E-04 -0.350466075 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific) "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0010507///negative regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0016577///histone demethylation+++GO:0031667///response to nutrient levels+++GO:0033169///histone H3-K9 demethylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0060548///negative regulation of cell death+++GO:0070544///histone H3-K36 demethylation+++GO:1900113///negative regulation of histone H3-K9 trimethylation" 230676 230676 'Szt2' mRNA 633 536 539 2.98 2.47 2.68 2.01 1.68 2.16 2.71 1.95 491 399 516 569.3333333 468.6666667 0.036491618 -0.293119949 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0061700///GATOR2 complex+++GO:0140007///KICSTOR complex+++GO:1990130///GATOR1 complex GO:0007417///central nervous system development+++GO:0009791///post-embryonic development+++GO:0021540///corpus callosum morphogenesis+++GO:0031667///response to nutrient levels+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0043473///pigmentation+++GO:0061462///protein localization to lysosome+++GO:1901668///regulation of superoxide dismutase activity+++GO:1904262///negative regulation of TORC1 signaling 230678 230678 'Tmem125' mRNA 257 254 238 7.5 7.12 7.48 5.05 5.15 4.17 7.366666667 4.79 202 192 155 249.6666667 183 0.012386145 -0.459843713 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 230696 230696 'AU022252' mRNA 775.38 797.74 805.45 10.77 10.35 10.54 9.64 9.77 9.62 10.55333333 9.676666667 733.97 734.69 714.97 792.8566667 727.8766667 0.230399154 -0.136969539 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 230700 230700 'Foxj3' mRNA 1313.14 1226.63 1214.59 12.94 11.89 12.85 9.93 8.13 10.26 12.56 9.44 1147.23 932.87 1139.71 1251.453333 1073.27 0.020902664 -0.23503482 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051321///meiotic cell cycle" 230709 230709 'Zmpste24' mRNA 1734 1767 1733 27.76 27.84 29.44 37.97 35.97 34.96 28.34666667 36.3 2730 2524 2435 1744.666667 2563 2.90E-14 0.541914212 00900///Terpenoid backbone biosynthesis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032991///protein-containing complex GO:0003690///double-stranded DNA binding+++GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0001889///liver development+++GO:0001942///hair follicle development+++GO:0003007///heart morphogenesis+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0003231///cardiac ventricle development+++GO:0003417///growth plate cartilage development+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006508///proteolysis+++GO:0006925///inflammatory cell apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006997///nucleus organization+++GO:0006998///nuclear envelope organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0007628///adult walking behavior+++GO:0008016///regulation of heart contraction+++GO:0008340///determination of adult lifespan+++GO:0008360///regulation of cell shape+++GO:0008544///epidermis development+++GO:0010506///regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010906///regulation of glucose metabolic process+++GO:0016485///protein processing+++GO:0019216///regulation of lipid metabolic process+++GO:0030282///bone mineralization+++GO:0030327///prenylated protein catabolic process+++GO:0030500///regulation of bone mineralization+++GO:0032006///regulation of TOR signaling+++GO:0032350///regulation of hormone metabolic process+++GO:0035264///multicellular organism growth+++GO:0040014///regulation of multicellular organism growth+++GO:0043007///maintenance of rDNA+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043969///histone H2B acetylation+++GO:0043979///histone H2B-K5 acetylation+++GO:0044029///hypomethylation of CpG island+++GO:0044030///regulation of DNA methylation+++GO:0044255///cellular lipid metabolic process+++GO:0048145///regulation of fibroblast proliferation+++GO:0048538///thymus development+++GO:0048739///cardiac muscle fiber development+++GO:0050688///regulation of defense response to virus+++GO:0050905///neuromuscular process+++GO:0051276///chromosome organization+++GO:0055013///cardiac muscle cell development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060993///kidney morphogenesis+++GO:0061337///cardiac conduction+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0070302///regulation of stress-activated protein kinase signaling cascade+++GO:0071480///cellular response to gamma radiation+++GO:0071586///CAAX-box protein processing+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0090239///regulation of histone H4 acetylation+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1903463///regulation of mitotic cell cycle DNA replication+++GO:1903522///regulation of blood circulation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:1990164///histone H2A phosphorylation+++GO:2000618///regulation of histone H4-K16 acetylation+++GO:2000730///regulation of termination of RNA polymerase I transcription+++GO:2000772///regulation of cellular senescence" 230718 230718 'Nt5c1a' mRNA 15 15 13 0.57 0.57 0.53 0.5 0.17 0.48 0.556666667 0.383333333 15 5 14 14.33333333 11.33333333 0.706410296 -0.354077166 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0050483///IMP 5'-nucleotidase activity GO:0000255///allantoin metabolic process+++GO:0006196///AMP catabolic process+++GO:0006204///IMP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0009128///purine nucleoside monophosphate catabolic process+++GO:0016311///dephosphorylation+++GO:0046055///dGMP catabolic process+++GO:0046059///dAMP catabolic process+++GO:0046085///adenosine metabolic process 230721 230721 'Pabpc4' mRNA 187 219 163 2.77 3.38 2.84 3.87 3.75 3.99 2.996666667 3.87 263 250 264 189.6666667 259 0.013131227 0.441634146 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding+++GO:0017130///poly(C) RNA binding GO:0043488///regulation of mRNA stability+++GO:0061515///myeloid cell development 230726 230726 'Rhbdl2' mRNA 11 24.34 10.06 0.4 0.94 0.45 1.55 1.35 2.1 0.596666667 1.666666667 39.49 32.17 45 15.13333333 38.88666667 0.010696791 1.364082112 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 230734 230734 'Yrdc' mRNA 309 345 63 11.69 12.87 2.53 3.95 3.75 7.08 9.03 4.926666667 120 111 208 239 146.3333333 0.437685035 -0.688785771 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane GO:0000049///tRNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0016779///nucleotidyltransferase activity GO:0006450///regulation of translational fidelity+++GO:0051051///negative regulation of transport 230735 230735 'Epha10' mRNA 123.49 110.72 106.93 2.57 2.25 2.3 2.38 2.15 2.02 2.373333333 2.183333333 130.95 115.85 107.06 113.7133333 117.9533333 0.886398437 0.042430593 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0048013///ephrin receptor signaling pathway 230737 230737 'Gnl2' mRNA 1340 1419 1290 31.88 33.23 32.64 22.19 26.72 21.64 32.58333333 23.51666667 1071 1261 1013 1349.666667 1115 0.006008097 -0.285042355 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0042254///ribosome biogenesis 230738 230738 'Zc3h12a' mRNA 72.53 73 43 1.43 1.41 0.9 2.34 1.68 2.24 1.246666667 2.086666667 136.94 95.93 126.53 62.84333333 119.8 0.001626611 0.919596226 GO:0000932///P-body+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0042588///zymogen granule+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004532///exoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0016787///hydrolase activity+++GO:0019902///phosphatase binding+++GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0035198///miRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding+++GO:0070492///oligosaccharide binding "GO:0000294///nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002757///immune response-activating signal transduction+++GO:0003309///type B pancreatic cell differentiation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007494///midgut development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010656///negative regulation of muscle cell apoptotic process+++GO:0010884///positive regulation of lipid storage+++GO:0010942///positive regulation of cell death+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0014070///response to organic cyclic compound+++GO:0016579///protein deubiquitination+++GO:0030154///cell differentiation+++GO:0031667///response to nutrient levels+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034599///cellular response to oxidative stress+++GO:0042060///wound healing+++GO:0042149///cellular response to glucose starvation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043434///response to peptide hormone+++GO:0044278///cell wall disruption in other organism+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050852///T cell receptor signaling pathway+++GO:0051259///protein complex oligomerization+++GO:0055074///calcium ion homeostasis+++GO:0055118///negative regulation of cardiac muscle contraction+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0097421///liver regeneration+++GO:0098586///cellular response to virus+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1903003///positive regulation of protein deubiquitination+++GO:1903492///response to acetylsalicylate+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:1903861///positive regulation of dendrite extension+++GO:1903936///cellular response to sodium arsenite+++GO:1904637///cellular response to ionomycin+++GO:1904692///positive regulation of type B pancreatic cell proliferation+++GO:1904699///positive regulation of acinar cell proliferation+++GO:1990785///response to water-immersion restraint stress+++GO:1990798///pancreas regeneration+++GO:1990864///response to growth hormone-releasing hormone+++GO:1990867///response to gastrin+++GO:1990869///cellular response to chemokine+++GO:1990878///cellular response to gastrin+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000627///positive regulation of miRNA catabolic process" 230751 230751 'Oscp1' mRNA 1538 1579 1460 16.37 16.51 16.47 3.17 3.22 3.65 16.45 3.346666667 343 341 383 1525.666667 355.6666667 5.15E-111 -2.111635595 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:1990961///drug transmembrane export 230752 230752 'Eva1b' mRNA 177 196 196 7.41 8 8.19 18.08 17.6 17 7.866666667 17.56 511 475 463 189.6666667 483 3.45E-21 1.335182446 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding 230753 230753 'Thrap3' mRNA 2140 2284 1782 26.18 27.44 23.11 22.62 21.84 22.08 25.57666667 22.18 2138 2011 2022 2068.666667 2057 0.873686914 -0.016022077 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016592///mediator complex+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046966///thyroid hormone receptor binding+++GO:0051219///phosphoprotein binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006366///transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0042753///positive regulation of circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0048255///mRNA stabilization+++GO:0048511///rhythmic process+++GO:0051028///mRNA transport" 230757 230757 '5730409E04Rik' mRNA 239 256 228 4.62 4.87 4.67 2.96 2.75 2.97 4.72 2.893333333 176 160 171 241 169 0.003135783 -0.523048902 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 230761 230761 'Zfp362' mRNA 1335 1398 1306 25.46 26.28 26.42 20.84 22.92 21.19 26.05333333 21.65 1257 1351 1238 1346.333333 1282 0.421160348 -0.081338402 04361///Axon regeneration GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity GO:0006357///regulation of transcription by RNA polymerase II 230766 230766 'Fam167b' mRNA 25 29 24 1.72 1.97 1.75 8.52 9.11 7.63 1.813333333 8.42 142 148 123 26 137.6666667 4.82E-16 2.394870025 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 230767 230767 'Iqcc' mRNA 526 530 476 13.07 13.45 12.44 9.36 10.18 9.72 12.98666667 9.753333333 417 447 403 510.6666667 422.3333333 0.026623412 -0.283668792 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 230770 230770 'Tmem39b' mRNA 320.49 338.02 305.17 6.92 7.19 6.45 10.77 10.15 10.95 6.853333333 10.62333333 521.73 484.33 512.39 321.2266667 506.15 2.30E-07 0.644545503 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 230775 230775 'Adgrb2' mRNA 156 164 141 1.61 1.68 1.57 0.42 0.49 0.57 1.62 0.493333333 46 53 60 153.6666667 53 6.11E-10 -1.544138495 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007422///peripheral nervous system development+++GO:0016525///negative regulation of angiogenesis+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0051965///positive regulation of synapse assembly 230779 230779 'Serinc2' mRNA 1458.37 1453.54 1416.97 43.2 42.41 44.72 45.75 45.36 41.84 43.44333333 44.31666667 1769.53 1705.21 1551.55 1442.96 1675.43 0.016194142 0.203423846 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006658///phosphatidylserine metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:1904219///positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:1904222///positive regulation of serine C-palmitoyltransferase activity 230784 230784 'Sesn2' mRNA 194 192 176 4.05 3.94 3.89 8.7 8.65 8.93 3.96 8.76 480 466 477 187.3333333 474.3333333 3.74E-22 1.329691387 04115///p53 signaling pathway+++04150///mTOR signaling pathway+++04211///Longevity regulating pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0031932///TORC2 complex+++GO:0061700///GATOR2 complex+++GO:1990316///Atg1/ULK1 kinase complex "GO:0005092///GDP-dissociation inhibitor activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0032542///sulfiredoxin activity+++GO:0044877///protein-containing complex binding+++GO:0051920///peroxiredoxin activity+++GO:0070728///leucine binding" "GO:0001932///regulation of protein phosphorylation+++GO:0006111///regulation of gluconeogenesis+++GO:0006635///fatty acid beta-oxidation+++GO:0007005///mitochondrion organization+++GO:0009749///response to glucose+++GO:0016239///positive regulation of macroautophagy+++GO:0030308///negative regulation of cell growth+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0032042///mitochondrial DNA metabolic process+++GO:0032868///response to insulin+++GO:0034198///cellular response to amino acid starvation+++GO:0034599///cellular response to oxidative stress+++GO:0036091///positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0042149///cellular response to glucose starvation+++GO:0042593///glucose homeostasis+++GO:0043491///protein kinase B signaling+++GO:0046323///glucose import+++GO:0070328///triglyceride homeostasis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:0072593///reactive oxygen species metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901031///regulation of response to reactive oxygen species+++GO:1902010///negative regulation of translation in response to endoplasmic reticulum stress+++GO:1904262///negative regulation of TORC1 signaling+++GO:1904504///positive regulation of lipophagy+++GO:1990253///cellular response to leucine starvation+++GO:2000479///regulation of cAMP-dependent protein kinase activity" 230787 230787 'Themis2' mRNA 147 133 167 2.54 2.05 3.04 18.81 20.67 19.04 2.543333333 19.50666667 1258 1337 1213 149 1269.333333 6.16E-134 3.07675794 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0050852///T cell receptor signaling pathway+++GO:0050864///regulation of B cell activation 230789 230789 'Fam76a' mRNA 1568 1583 1497 28.36 28.25 28.76 24.64 25.34 23.58 28.45666667 24.52 1558 1568 1444 1549.333333 1523.333333 0.739263611 -0.035717419 GO:0005654///nucleoplasm 230793 230793 'Ahdc1' mRNA 639 645 386 5 4.82 3.25 3.75 3.27 3.6 4.356666667 3.54 550 464 515 556.6666667 509.6666667 0.497394612 -0.130026332 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 230796 230796 'Wdtc1' mRNA 1012 1142 656 13.6 15.09 9.49 7.5 9.06 8.55 12.72666667 8.37 643 750 709 936.6666667 700.6666667 0.006001429 -0.418083595 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0004857///enzyme inhibitor activity+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006006///glucose metabolic process+++GO:0008361///regulation of cell size+++GO:0016567///protein ubiquitination+++GO:0032869///cellular response to insulin stimulus+++GO:0035264///multicellular organism growth+++GO:0043086///negative regulation of catalytic activity+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0055082///cellular chemical homeostasis 230801 230801 'Pigv' mRNA 864.81 826.06 912.01 17.07 16.01 18.58 13.84 13.16 11.44 17.22 12.81333333 786.21 723.73 634.05 867.6266667 714.6633333 0.0128847 -0.295485969 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031501///mannosyltransferase complex "GO:0000009///alpha-1,6-mannosyltransferase activity+++GO:0000030///mannosyltransferase activity+++GO:0004376///glycolipid mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006506///GPI anchor biosynthetic process+++GO:0097502///mannosylation 230806 230806 'Crybg2' mRNA 5 4 10 0.06 0.04 0.12 0.11 0.22 0.26 0.073333333 0.196666667 11 22 25 6.333333333 19.33333333 0.045648159 1.588980939 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0030246///carbohydrate binding GO:0008150///biological_process 230809 230809 'Pdik1l' mRNA 416 444 384 4.93 5.18 4.83 4.27 4.38 4.49 4.98 4.38 414 415 421 414.6666667 416.6666667 0.994139137 -0.002756281 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051321///meiotic cell cycle 230810 230810 'Slc30a2' mRNA 46 73 46 0.81 1.2 0.8 0.9 1.24 0.95 0.936666667 1.03 60 82 64 55 68.66666667 0.427746739 0.316756389 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005385///zinc ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008324///cation transmembrane transporter activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0010043///response to zinc ion+++GO:0055085///transmembrane transport+++GO:0061088///regulation of sequestering of zinc ion+++GO:0061090///positive regulation of sequestering of zinc ion+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport 230815 230815 'Man1c1' mRNA 274 277 276 3.86 4.07 4.25 8.99 7.44 8.93 4.06 8.453333333 705 572 687 275.6666667 654.6666667 3.32E-22 1.234162625 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0006491///N-glycan processing+++GO:0008152///metabolic process+++GO:0030166///proteoglycan biosynthetic process 230822 230822 'Ncmap' mRNA 6473 6634 6105 236.75 238.57 235.79 112.09 111.07 102.96 237.0366667 108.7066667 3501 3437 3146 6404 3361.333333 2.85E-58 -0.941040056 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033270///paranode region of axon+++GO:0043220///Schmidt-Lanterman incisure GO:0019911///structural constituent of myelin sheath GO:0031641///regulation of myelination+++GO:0031643///positive regulation of myelination+++GO:0032290///peripheral nervous system myelin formation 230824 230824 'Grhl3' mRNA 6 4 5 0.12 0.08 0.1 0.1 0.07 0.12 0.1 0.096666667 6 4 7 5 5.666666667 0.900957194 0.16542426 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016581///NuRD complex+++GO:0016607///nuclear speck+++GO:0043529///GET complex "GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0031490///chromatin DNA binding+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061628///H3K27me3 modified histone binding+++GO:0070615///nucleosome-dependent ATPase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001736///establishment of planar polarity+++GO:0001843///neural tube closure+++GO:0001964///startle response+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0007283///spermatogenesis+++GO:0007389///pattern specification process+++GO:0007398///ectoderm development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0008544///epidermis development+++GO:0010628///positive regulation of gene expression+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030154///cell differentiation+++GO:0032508///DNA duplex unwinding+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0042060///wound healing+++GO:0043547///positive regulation of GTPase activity+++GO:0043967///histone H4 acetylation+++GO:0045048///protein insertion into ER membrane+++GO:0045595///regulation of cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0061029///eyelid development in camera-type eye+++GO:0061436///establishment of skin barrier+++GO:0071599///otic vesicle development+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0098532///histone H3-K27 trimethylation+++GO:1901798///positive regulation of signal transduction by p53 class mediator" 230828 230828 'Il22ra1' mRNA 12 12 7 0.11 0.11 0.07 0.02 0.01 0.05 0.096666667 0.026666667 2 1 6 10.33333333 3 0.109628611 -1.785547114 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04630///JAK-STAT signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0042015///interleukin-20 binding GO:0019221///cytokine-mediated signaling pathway+++GO:0050829///defense response to Gram-negative bacterium 230837 230837 'Asap3' mRNA 1332.02 1402.99 1491 12.62 13.06 15.01 13.06 12.35 11.69 13.56333333 12.36666667 1587.03 1463 1371 1408.67 1473.676667 0.689061634 0.050033069 04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0043231///intracellular membrane-bounded organelle GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0016477///cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0051492///regulation of stress fiber assembly 230848 230848 'Zbtb40' mRNA 393 329 383 2.85 2.33 2.94 1.37 1.31 1.4 2.706666667 1.36 218 204 215 368.3333333 212.3333333 2.88E-07 -0.809390845 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus 230857 230857 'Ece1' mRNA 2533 2456 2465 28.91 27.62 29.91 21.62 20.87 20.86 28.81333333 21.11666667 2177 2049 2034 2484.666667 2086.666667 1.88E-04 -0.264738068 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0033093///Weibel-Palade body+++GO:0048471///perinuclear region of cytoplasm GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001666///response to hypoxia+++GO:0001921///positive regulation of receptor recycling+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007507///heart development+++GO:0008217///regulation of blood pressure+++GO:0010467///gene expression+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010814///substance P catabolic process+++GO:0010815///bradykinin catabolic process+++GO:0010816///calcitonin catabolic process+++GO:0016485///protein processing+++GO:0016486///peptide hormone processing+++GO:0031175///neuron projection development+++GO:0034959///endothelin maturation+++GO:0035050///embryonic heart tube development+++GO:0042447///hormone catabolic process+++GO:0042733///embryonic digit morphogenesis+++GO:0043583///ear development+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0060037///pharyngeal system development+++GO:0060385///axonogenesis involved in innervation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0097492///sympathetic neuron axon guidance+++GO:0097746///regulation of blood vessel diameter+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 230861 230861 'Eif4g3' mRNA 1350 1465 1020 11.38 12.01 9.01 8.2 8.23 9.1 10.8 8.51 1136 1109 1206 1278.333333 1150.333333 0.182121412 -0.157072263 05416///Viral myocarditis GO:0016281///eukaryotic translation initiation factor 4F complex GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0007283///spermatogenesis+++GO:0045727///positive regulation of translation+++GO:0060903///positive regulation of meiosis I 230863 230863 'Sh2d5' mRNA 29 34 34 0.51 0.58 0.63 0.53 0.62 0.47 0.573333333 0.54 35 40 30 32.33333333 35 0.863090843 0.101726873 GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005515///protein binding GO:0008150///biological_process 230866 230866 'Emc1' mRNA 2970.01 2950.01 3079.24 25.26 24.67 27.78 22.44 20.27 20.39 25.90333333 21.03333333 3036.02 2680.74 2673.02 2999.753333 2796.593333 0.166629141 -0.116121185 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 230868 230868 'Igsf21' mRNA 283 311 338 8.07 8.76 10.23 0.82 0.99 0.51 9.02 0.773333333 33 39 20 310.6666667 30.66666667 3.17E-42 -3.355911955 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse GO:0005515///protein binding GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0060074///synapse maturation 230872 230872 'Crocc' mRNA 148 140 93 1.21 1.11 0.82 0.43 0.44 0.52 1.046666667 0.463333333 62 60 70 127 64 2.85E-04 -0.992266979 GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0015629///actin cytoskeleton+++GO:0035253///ciliary rootlet+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019894///kinesin binding GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0008104///protein localization+++GO:0010457///centriole-centriole cohesion+++GO:0010669///epithelial structure maintenance+++GO:0030030///cell projection organization+++GO:0032053///ciliary basal body organization+++GO:0033365///protein localization to organelle+++GO:0045494///photoreceptor cell maintenance+++GO:0045724///positive regulation of cilium assembly+++GO:0051656///establishment of organelle localization+++GO:1903566///positive regulation of protein localization to cilium 230895 230895 'Vps13d' mRNA 870 927 867 2.87 3.02 3.04 3.03 2.62 3.07 2.976666667 2.906666667 1056 889 1038 888 994.3333333 0.162349111 0.150520168 GO:0019898///extrinsic component of membrane GO:0003674///molecular_function GO:0006623///protein targeting to vacuole+++GO:0007005///mitochondrion organization+++GO:0045053///protein retention in Golgi apparatus+++GO:1901526///positive regulation of mitophagy 230899 230899 'Nppa' mRNA 3 1 2 0.23 0.08 0.16 0.07 0.07 0.14 0.156666667 0.093333333 1 1 2 2 1.333333333 0.813136065 -0.59863572 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04270///Vascular smooth muscle contraction+++04714///Thermogenesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++05143///African trypanosomiasis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0032991///protein-containing complex+++GO:0042629///mast cell granule+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0051427///hormone receptor binding+++GO:0071855///neuropeptide receptor binding GO:0001666///response to hypoxia+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006182///cGMP biosynthetic process+++GO:0006457///protein folding+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007565///female pregnancy+++GO:0008217///regulation of blood pressure+++GO:0010460///positive regulation of heart rate+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0019934///cGMP-mediated signaling+++GO:0030308///negative regulation of cell growth+++GO:0032868///response to insulin+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042311///vasodilation+++GO:0043508///negative regulation of JUN kinase activity+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0071260///cellular response to mechanical stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:1903595///positive regulation of histamine secretion by mast cell+++GO:1903766///positive regulation of potassium ion export across plasma membrane+++GO:1903815///negative regulation of collecting lymphatic vessel constriction 230903 230903 'Fbxo44' mRNA 2833 2886 2761 100.21 102.03 103.95 80.08 81.42 82.47 102.0633333 81.32333333 2549 2524 2573 2826.666667 2548.666667 0.01738698 -0.160973824 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006516///glycoprotein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 230904 230904 'Fbxo2' mRNA 28684 28913 19989 1417.26 1411.17 1048.51 518.85 907.07 785.79 1292.313333 737.2366667 12054 20541 17639 25862 16744.66667 0.033067672 -0.625084533 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006516///glycoprotein catabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031396///regulation of protein ubiquitination 230908 230908 'Tardbp' mRNA 2275.32 2253.75 2117.01 16.31 15.95 16.19 15.99 15.9 16.76 16.15 16.21666667 2560.5 2478.99 2593.69 2215.36 2544.393333 0.005478894 0.188497121 03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005726///perichromatin fibrils+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0035061///interchromatin granule GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0097157///pre-mRNA intronic binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0031647///regulation of protein stability+++GO:0032024///positive regulation of insulin secretion+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042752///regulation of circadian rhythm+++GO:0042981///regulation of apoptotic process+++GO:0043922///negative regulation by host of viral transcription+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0071765///nuclear inner membrane organization 230909 230909 'Gm572' mRNA 1 0 0 0.04 0 0 0 0.02 0 0.013333333 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007368///determination of left/right symmetry+++GO:0007507///heart development 230917 230917 'Tmem201' mRNA 1612 1634 1558 23.89 23.86 24.52 12.4 10.82 12.34 24.09 11.85333333 960 815 928 1601.333333 901 1.06E-23 -0.842344003 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031616///spindle pole centrosome+++GO:0031965///nuclear membrane+++GO:0032541///cortical endoplasmic reticulum GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0051015///actin filament binding GO:0006998///nuclear envelope organization+++GO:0007097///nuclear migration+++GO:0010761///fibroblast migration+++GO:0030473///nuclear migration along microtubule+++GO:0051642///centrosome localization+++GO:0090435///protein localization to nuclear envelope 230935 230935 'Dnajc11' mRNA 1146 1233 1135 21.02 22.15 22.15 19.16 20.35 19.46 21.77333333 19.65666667 1192 1241 1171 1171.333333 1201.333333 0.836000484 0.025665656 GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0061617///MICOS complex GO:0042407///cristae formation 230936 230936 'Phf13' mRNA 777 733 389 13.61 12.63 7.23 6.82 10.11 9 11.15666667 8.643333333 448 649 573 633 556.6666667 0.687194161 -0.179039931 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003682///chromatin binding+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0051301///cell division 230959 230959 'Ajap1' mRNA 13 17 13 0.28 0.35 0.3 0.1 0.16 0.08 0.31 0.113333333 5 8 4 14.33333333 5.666666667 0.116577565 -1.344722841 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0044214///spanning component of plasma membrane+++GO:0044291///cell-cell contact zone GO:0008013///beta-catenin binding+++GO:0044877///protein-containing complex binding GO:0001953///negative regulation of cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0030860///regulation of polarized epithelial cell differentiation+++GO:0061045///negative regulation of wound healing 230967 230967 'Cep104' mRNA 1266 1358 1165 14.74 15.5 14.05 6.91 6.73 7.48 14.76333333 7.04 696 646 683 1263 675 1.28E-25 -0.913964273 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0016596///thienylcyclohexylpiperidine binding GO:0008150///biological_process 230971 230971 'Megf6' mRNA 166 216 213 1.29 1.65 1.78 0.33 0.52 0.59 1.573333333 0.48 49 74 82 198.3333333 68.33333333 7.60E-10 -1.548499157 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding GO:0008150///biological_process 230972 230972 'Arhgef16' mRNA 458 446 419 9.03 8.8 8.76 7.83 7.76 8.48 8.863333333 8.023333333 450 438 473 441 453.6666667 0.863090843 0.030014707 GO:0005737///cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031267///small GTPase binding GO:0060326///cell chemotaxis+++GO:0090630///activation of GTPase activity+++GO:1903078///positive regulation of protein localization to plasma membrane 230979 230979 'Tnfrsf14' mRNA 473.4 428.73 410.25 5.39 4.78 4.96 11.5 10.52 10.7 5.043333333 10.90666667 1169.25 1037.01 1048.48 437.46 1084.913333 1.82E-38 1.299826506 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++05168///Herpes simplex virus 1 infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0031625///ubiquitin protein ligase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0016032///viral process+++GO:0031295///T cell costimulation+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0046642///negative regulation of alpha-beta T cell proliferation+++GO:0046718///viral entry into host cell+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:1905675///negative regulation of adaptive immune memory response+++GO:2000406///positive regulation of T cell migration 230991 230991 'Fndc10' mRNA 212 209 140 5.68 5.56 4 4.24 3.93 5.32 5.08 4.496666667 180 162 220 187 187.3333333 0.998591786 -0.001731216 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 230996 230996 '9430015G10Rik' mRNA 262 261 288 5.77 5.57 6.73 4.32 4.29 4.38 6.023333333 4.33 228 220 224 270.3333333 224 0.10937316 -0.285905294 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 231002 231002 'Plekhn1' mRNA 276 290 246 7.15 7.37 6.74 5.47 5.46 5.04 7.086666667 5.323333333 243 238 217 270.6666667 232.6666667 0.197871558 -0.227862195 GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0070300///phosphatidic acid binding+++GO:1901612///cardiolipin binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0001666///response to hypoxia+++GO:0043065///positive regulation of apoptotic process+++GO:0061158///3'-UTR-mediated mRNA destabilization 231003 231003 'Klhl17' mRNA 257 288 216 4.68 5.16 4.17 3.59 2.72 3.56 4.67 3.29 227 168 218 253.6666667 204.3333333 0.100563502 -0.321170681 GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0032839///dendrite cytoplasm+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0003779///actin binding+++GO:0031208///POZ domain binding+++GO:0051015///actin filament binding+++GO:0060090///molecular adaptor activity GO:0007420///brain development+++GO:0016567///protein ubiquitination+++GO:0030036///actin cytoskeleton organization 231004 231004 'Samd11' mRNA 588.56 562.58 560.2 12.32 11.08 11.98 2.26 2.16 1.59 11.79333333 2.003333333 124.28 117.41 85.85 570.4466667 109.18 2.72E-52 -2.404004769 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0032093///SAM domain binding+++GO:0042393///histone binding+++GO:0042731///PH domain binding+++GO:0043621///protein self-association "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 231014 231014 'Elapor2' mRNA 10 14 16 0.07 0.13 0.16 0.11 0.15 0.14 0.12 0.133333333 10 17 12 13.33333333 13 0.958517969 -0.050123742 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0070700///BMP receptor binding GO:0030513///positive regulation of BMP signaling pathway+++GO:0045684///positive regulation of epidermis development+++GO:0051961///negative regulation of nervous system development 231042 231042 'Nupl2' mRNA 295 388 298 5.42 6.88 5.8 4.67 3.91 4.1 6.033333333 4.226666667 291 237 247 327 258.3333333 0.042318513 -0.350408768 03013///Nucleocytoplasmic transport GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0005049///nuclear export signal receptor activity+++GO:0046872///metal ion binding GO:0006611///protein export from nucleus+++GO:0015031///protein transport+++GO:0051028///mRNA transport 231050 231050 'Galnt11' mRNA 1185 1295 1214 25.88 27.82 28.28 19.77 19.03 19.13 27.32666667 19.31 1031 985 975 1231.333333 997 3.14E-04 -0.316634453 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0005112///Notch binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007368///determination of left/right symmetry+++GO:0008593///regulation of Notch signaling pathway+++GO:0018243///protein O-linked glycosylation via threonine+++GO:0060271///cilium assembly+++GO:0061314///Notch signaling involved in heart development 231051 231051 'Kmt2c' mRNA 2776 2936 2244 9.06 9.36 7.48 4.26 4.17 4.98 8.633333333 4.47 1582 1490 1731 2652 1601 8.82E-18 -0.734889735 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex "GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042393///histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding" "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007338///single fertilization+++GO:0010468///regulation of gene expression+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0035264///multicellular organism growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051568///histone H3-K4 methylation+++GO:0061029///eyelid development in camera-type eye+++GO:0097692///histone H3-K4 monomethylation" 231070 231070 'Insig1' mRNA 2905 2846 2955 60.83 58.66 65.64 29.02 28.15 27.86 61.71 28.34333333 1594 1510 1482 2902 1528.666667 4.64E-38 -0.938614547 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032937///SREBP-SCAP-Insig complex GO:0005515///protein binding+++GO:0008142///oxysterol binding+++GO:0008289///lipid binding GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006991///response to sterol depletion+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0032869///cellular response to insulin stimulus+++GO:0032933///SREBP signaling pathway+++GO:0036315///cellular response to sterol+++GO:0036316///SREBP-SCAP complex retention in endoplasmic reticulum+++GO:0042472///inner ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042632///cholesterol homeostasis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0060021///roof of mouth development+++GO:0060363///cranial suture morphogenesis+++GO:0070862///negative regulation of protein exit from endoplasmic reticulum+++GO:1901303///negative regulation of cargo loading into COPII-coated vesicle 231086 231086 'Hadhb' mRNA 4950 5161 5237 137.27 140.94 154.13 132.37 138.54 131.85 144.1133333 134.2533333 5496 5597 5287 5116 5460 0.299225668 0.08062208 "00062///Fatty acid elongation+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++01212///Fatty acid metabolism" GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016507///mitochondrial fatty acid beta-oxidation multienzyme complex+++GO:0042645///mitochondrial nucleoid "GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0044877///protein-containing complex binding+++GO:0050633///acetyl-CoA C-myristoyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation 231093 231093 'Agbl5' mRNA 483.61 468.49 308.32 8.04 7.66 5.49 3.76 3.46 3.84 7.063333333 3.686666667 261.27 232.21 260.2 420.14 251.2266667 8.09E-06 -0.745543728 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0035608///protein deglutamylation+++GO:0035610///protein side chain deglutamylation+++GO:0035611///protein branching point deglutamylation+++GO:0051607///defense response to virus 231103 231103 'Gckr' mRNA 13 14 13 0.34 0.36 0.34 0.16 0.11 0.14 0.346666667 0.136666667 7 5 6 13.33333333 6 0.178003696 -1.165456224 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004857///enzyme inhibitor activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0070095///fructose-6-phosphate binding+++GO:0097367///carbohydrate derivative binding GO:0001678///cellular glucose homeostasis+++GO:0005975///carbohydrate metabolic process+++GO:0006606///protein import into nucleus+++GO:0009750///response to fructose+++GO:0033132///negative regulation of glucokinase activity+++GO:0033133///positive regulation of glucokinase activity+++GO:0034504///protein localization to nucleus+++GO:0042593///glucose homeostasis+++GO:0046415///urate metabolic process+++GO:0070328///triglyceride homeostasis+++GO:1901135///carbohydrate derivative metabolic process+++GO:1903300///negative regulation of hexokinase activity 231123 231123 'Haus3' mRNA 409 498 441 11.95 14.33 13.67 20.33 18.38 20.35 13.31666667 19.68666667 800 706 775 449.3333333 760.3333333 6.66E-11 0.746768289 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge+++GO:0070652///HAUS complex+++GO:0072686///mitotic spindle+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 231125 231125 'Zfyve28' mRNA 270.62 226.11 157.93 3.8 3.15 2.55 1.91 2.23 2.25 3.166666667 2.13 152.6 154.54 155.2 218.22 154.1133333 0.021330518 -0.505681394 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031901///early endosome membrane GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0046872///metal ion binding GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway 231128 231128 'Fam193a' mRNA 520 510 494 4.99 4.82 5.03 4.34 3.93 4.7 4.946666667 4.323333333 520 460 546 508 508.6666667 0.950866287 -0.010294577 GO:0003674///molecular_function GO:0008150///biological_process 231130 231130 'Tnip2' mRNA 356 305 330 10.33 8.72 10.16 15.4 14.92 14.92 9.736666667 15.08 610 577 572 330.3333333 586.3333333 6.64E-11 0.814740646 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0023035///CD40 signaling pathway+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0043032///positive regulation of macrophage activation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0050871///positive regulation of B cell activation+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:2000352///negative regulation of endothelial cell apoptotic process 231134 231134 'Dok7' mRNA 507 555 530 9.83 10.55 10.8 4.83 4.96 5.07 10.39333333 4.953333333 281 285 290 530.6666667 285.3333333 1.20E-12 -0.907092681 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0035091///phosphatidylinositol binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007528///neuromuscular junction development+++GO:0043113///receptor clustering+++GO:0061098///positive regulation of protein tyrosine kinase activity 231147 231147 'Sh3tc1' mRNA 74 110 96 0.97 1.42 1.42 3.02 3.23 3.29 1.27 3.18 281 280 283 93.33333333 281.3333333 9.25E-16 1.580043531 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 231148 231148 'Ablim2' mRNA 1310 1339 1302 19.96 20.24 20.99 2.62 1.84 2.24 20.39666667 2.233333333 196 130 163 1317 163 1.48E-134 -3.028740865 04360///Axon guidance GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril GO:0003779///actin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding "GO:0006351///transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0045944///positive regulation of transcription by RNA polymerase II" 231151 231151 'Tada2b' mRNA 151.02 193.54 146.55 2.18 2.79 2.29 1.95 2.11 2.21 2.42 2.09 154.41 160.94 168.4 163.7033333 161.25 0.904055975 -0.03153721 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0030914///STAGA complex+++GO:0070461///SAGA-type complex GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035065///regulation of histone acetylation+++GO:0035066///positive regulation of histone acetylation+++GO:0045893///positive regulation of transcription, DNA-templated" 231162 231162 'Cytl1' mRNA 36 37 29 2.38 2.42 2.03 1.84 3.02 3.04 2.276666667 2.633333333 32 51 51 34 44.66666667 0.416704324 0.389779492 GO:0005575///cellular_component GO:0002062///chondrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1990079///cartilage homeostasis 231201 231201 'AF366264' mRNA 15.73 17.09 12.17 0.26 0.27 0.21 0.17 0.09 0.24 0.246666667 0.166666667 12.15 6.01 16.58 14.99666667 11.58 0.674676831 -0.380917618 03013///Nucleocytoplasmic transport+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005829///cytosol GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016929///SUMO-specific protease activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization 231207 231207 'Cpeb2' mRNA 935 1001 811 7 7.34 6.43 5.4 4.98 5.32 6.923333333 5.233333333 826 747 794 915.6666667 789 0.028513486 -0.223906534 04114///Oocyte meiosis+++04320///Dorso-ventral axis formation+++04914///Progesterone-mediated oocyte maturation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:1990124///messenger ribonucleoprotein complex "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005095///GTPase inhibitor activity+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding+++GO:0008187///poly-pyrimidine tract binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0043022///ribosome binding+++GO:0043023///ribosomal large subunit binding+++GO:0043024///ribosomal small subunit binding+++GO:0045182///translation regulator activity" GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0032869///cellular response to insulin stimulus+++GO:0034260///negative regulation of GTPase activity+++GO:0034599///cellular response to oxidative stress+++GO:0045900///negative regulation of translational elongation+++GO:0071243///cellular response to arsenic-containing substance+++GO:0071456///cellular response to hypoxia+++GO:1900248///negative regulation of cytoplasmic translational elongation+++GO:2000766///negative regulation of cytoplasmic translation 231214 231214 'Cc2d2a' mRNA 546 554 547 5.36 5.38 5.71 3.4 2.99 3.41 5.483333333 3.266666667 392 342 379 549 371 2.34E-06 -0.578531089 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection GO:0005515///protein binding GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0043010///camera-type eye development+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:1904491///protein localization to ciliary transition zone+++GO:1905515///non-motile cilium assembly+++GO:1990403///embryonic brain development 231225 231225 'Tapt1' mRNA 325 403 355 5.05 6.15 5.85 4.69 4.6 5.28 5.683333333 4.856666667 348 333 379 361 353.3333333 0.841473424 -0.042232702 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0001503///ossification+++GO:0007275///multicellular organism development+++GO:0014032///neural crest cell development+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0035437///maintenance of protein localization in endoplasmic reticulum+++GO:0045724///positive regulation of cilium assembly+++GO:0048706///embryonic skeletal system development+++GO:0048856///anatomical structure development+++GO:0051216///cartilage development+++GO:0061036///positive regulation of cartilage development+++GO:1903012///positive regulation of bone development 231238 231238 'Sel1l3' mRNA 2065 2112 2023 24.56 24.7 25.52 20.66 20.67 20.98 24.92666667 20.77 2000 1954 1967 2066.666667 1973.666667 0.332648747 -0.07823398 GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 231252 231252 'Chrna9' mRNA 1990 2112 2054 58.13 60.84 63.45 4.25 4.94 5.53 60.80666667 4.906666667 172 183 208 2052 187.6666667 3.98E-240 -3.462852491 04080///Neuroactive ligand-receptor interaction+++05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098981///cholinergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007605///sensory perception of sound+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042472///inner ear morphogenesis+++GO:0050877///nervous system process+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 231279 231279 'Guf1' mRNA 1412 1536 531 15.3 16.39 6.48 3.01 4.1 4.1 12.72333333 3.736666667 295 422 405 1159.666667 374 8.36E-04 -1.618909009 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0043022///ribosome binding+++GO:0097177///mitochondrial ribosome binding GO:0006412///translation+++GO:0045727///positive regulation of translation 231290 231290 'Slc10a4' mRNA 10 16 16 0.27 0.43 0.46 0.31 0.31 0.2 0.386666667 0.273333333 13 13 8 14 11.33333333 0.731796867 -0.321144229 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0098691///dopaminergic synapse+++GO:0098981///cholinergic synapse+++GO:0099154///serotonergic synapse GO:0008508///bile acid:sodium symporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0009410///response to xenobiotic stimulus+++GO:0015721///bile acid and bile salt transport+++GO:0030534///adult behavior+++GO:0042493///response to drug+++GO:0055085///transmembrane transport+++GO:0099162///regulation of neurotransmitter loading into synaptic vesicle 231293 231293 'Cwh43' mRNA 14 16 23 0.31 0.32 0.52 0.08 0.14 0.17 0.383333333 0.13 4 7 8 17.66666667 6.333333333 0.056359143 -1.498514196 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006506///GPI anchor biosynthetic process 231296 231296 'Lrrc66' mRNA 0 0 1 0 0 0.02 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0016020///membrane+++GO:0016021///integral component of membrane 231326 231326 'Aasdh' mRNA 367 372 400 3.98 3.92 4.66 2.65 2.43 2.29 4.186666667 2.456666667 270 237 238 379.6666667 248.3333333 2.99E-05 -0.627668827 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016878///acid-thiol ligase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0019482///beta-alanine metabolic process+++GO:0043041///amino acid activation for nonribosomal peptide biosynthetic process 231327 231327 'Ppat' mRNA 407 438.8 383 5.48 5.81 5.47 4.45 4.81 3.97 5.586666667 4.41 380.28 401.45 329 409.6 370.2433333 0.327049982 -0.155622712 "00230///Purine metabolism+++00250///Alanine, aspartate and glutamate metabolism" GO:0004044///amidophosphoribosyltransferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001822///kidney development+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006543///glutamine catabolic process+++GO:0007595///lactation+++GO:0009113///purine nucleobase biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0019693///ribose phosphate metabolic process+++GO:0031100///animal organ regeneration+++GO:0032869///cellular response to insulin stimulus+++GO:0035690///cellular response to drug+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0060135///maternal process involved in female pregnancy+++GO:0097294///'de novo' XMP biosynthetic process 231329 231329 'Polr2b' mRNA 1884 1866 1943 26.75 26.06 29.26 21.62 22.87 20.7 27.35666667 21.73 1753 1811 1625 1897.666667 1729.666667 0.105594661 -0.146995959 03020///RNA polymerase+++05016///Huntington disease "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex" GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0032549///ribonucleoside binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 231380 231380 'Uba6' mRNA 278 249 265 2.91 2.56 2.94 3.05 2.69 2.68 2.803333333 2.806666667 335 289 285 264 303 0.301080118 0.184742454 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004839///ubiquitin activating enzyme activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity+++GO:0019780///FAT10 activating enzyme activity GO:0006464///cellular protein modification process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007612///learning+++GO:0007626///locomotory behavior+++GO:0016567///protein ubiquitination+++GO:0021764///amygdala development+++GO:0021766///hippocampus development+++GO:0032446///protein modification by small protein conjugation+++GO:0060996///dendritic spine development 231386 231386 'Ythdc1' mRNA 1001.07 1093.13 563.59 16.2 17.54 9.77 8.08 9.37 9.9 14.50333333 9.116666667 559.96 651 676 885.93 628.9866667 0.111241566 -0.490344339 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0016607///nuclear speck GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:1990247///N6-methyladenosine-containing RNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0007283///spermatogenesis+++GO:0008380///RNA splicing+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0048160///primary follicle stage+++GO:0110104///mRNA alternative polyadenylation" 231413 231413 'Grsf1' mRNA 1498 1524 782 33 32.73 19.04 14.54 15.83 17.34 28.25666667 15.90333333 732 789 871 1268 797.3333333 0.031341828 -0.665260171 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0000962///positive regulation of mitochondrial RNA catabolic process+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0009952///anterior/posterior pattern specification+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0043484///regulation of RNA splicing 231430 231430 'Cox18' mRNA 383.04 439.94 417.02 16.27 18.83 19.24 24.04 22.94 22.79 18.11333333 23.25666667 635.51 600.13 573.03 413.3333333 602.89 1.11E-05 0.532457731 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0032977///membrane insertase activity GO:0008535///respiratory chain complex IV assembly+++GO:0032979///protein insertion into mitochondrial inner membrane from matrix side+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0051204///protein insertion into mitochondrial membrane+++GO:0051205///protein insertion into membrane+++GO:0090150///establishment of protein localization to membrane 231440 231440 'Parm1' mRNA 345 384 316 9.31 10.2 9.04 9.24 8.7 7.34 9.516666667 8.426666667 394 362 303 348.3333333 353 0.966783975 0.009072982 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0051973///positive regulation of telomerase activity 231452 231452 'Sdad1' mRNA 358 347 299 3.81 3.63 3.37 4.29 3.87 4.29 3.603333333 4.15 464 409 450 334.6666667 441 0.004246388 0.388071064 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0000055///ribosomal large subunit export from nucleus+++GO:0015031///protein transport+++GO:0030036///actin cytoskeleton organization+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:1990830///cellular response to leukemia inhibitory factor 231464 231464 'Cnot6l' mRNA 752 803 725 4.55 4.77 4.68 3.92 3.46 4.42 4.666666667 3.933333333 743 641 813 760 732.3333333 0.65292602 -0.064935905 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030014///CCR4-NOT complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0008284///positive regulation of cell proliferation+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0031047///gene silencing by RNA+++GO:0061157///mRNA destabilization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 231470 231470 'Fras1' mRNA 732 721 609 2.29 2.27 2.09 0.81 0.69 0.76 2.216666667 0.753333333 296 241 260 687.3333333 265.6666667 4.43E-29 -1.381463301 04512///ECM-receptor interaction GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0002009///morphogenesis of an epithelium+++GO:0003338///metanephros morphogenesis+++GO:0007154///cell communication+++GO:0015031///protein transport+++GO:0030326///embryonic limb morphogenesis+++GO:0043588///skin development+++GO:0060021///roof of mouth development 231474 231474 'Paqr3' mRNA 356.12 407.01 416.92 8.36 8.49 9.97 9.08 9.56 10.35 8.94 9.663333333 449.08 470.32 507.64 393.35 475.68 0.076083103 0.261182418 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0001933///negative regulation of protein phosphorylation+++GO:0010977///negative regulation of neuron projection development+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0034067///protein localization to Golgi apparatus+++GO:0043407///negative regulation of MAP kinase activity 231503 231503 'Tmem150c' mRNA 230 236 117 4.5 4.57 2.41 0.82 0.91 0.9 3.826666667 0.876666667 48 52 51 194.3333333 50.33333333 2.54E-12 -1.946361075 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008381///mechanosensitive ion channel activity GO:0010506///regulation of autophagy+++GO:0019230///proprioception+++GO:0034220///ion transmembrane transport+++GO:0071260///cellular response to mechanical stimulus 231506 231506 'Lin54' mRNA 282 270 206 3.4 3.19 2.73 1.91 2.66 2.28 3.106666667 2.283333333 175 242 206 252.6666667 207.6666667 0.173377816 -0.286623862 04218///Cellular senescence GO:0005634///nucleus GO:0001067///regulatory region nucleic acid binding+++GO:0003677///DNA binding+++GO:0003680///AT DNA binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle" 231507 231507 'Plac8' mRNA 41 47 35 4.06 4.34 3.66 107.33 114.78 108.97 4.02 110.36 1229 1281 1208 41 1239.333333 1.05E-197 4.908553759 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0008284///positive regulation of cell proliferation+++GO:0009409///response to cold+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050873///brown fat cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis 231510 231510 'Gpat3' mRNA 40 45 57 0.77 0.85 1.16 4.53 3.44 3.21 0.926666667 3.726666667 273 202 187 47.33333333 220.6666667 2.08E-18 2.201096151 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0004366///glycerol-3-phosphate O-acyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0102420///sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity" GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0032006///regulation of TOR signaling 231532 231532 'Arhgap24' mRNA 925 957 932 14.24 14.52 15.04 8.03 7.48 8.62 14.6 8.043333333 599 554 615 938 589.3333333 4.34E-12 -0.683048437 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0005096///GTPase activator activity "GO:0001525///angiogenesis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity+++GO:1900028///negative regulation of ruffle assembly" 231549 231549 'Lrrc8d' mRNA 2242 2302 1844 30.5 30.73 26.88 23.68 23.15 23.06 29.37 23.29666667 1995 1872 1871 2129.333333 1912.666667 0.046084555 -0.163013709 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034702///ion channel complex GO:0005225///volume-sensitive anion channel activity GO:0001678///cellular glucose homeostasis+++GO:0006811///ion transport+++GO:0015698///inorganic anion transport+++GO:0015734///taurine transport+++GO:0015810///aspartate transmembrane transport+++GO:0034214///protein hexamerization+++GO:0071470///cellular response to osmotic stress+++GO:0098656///anion transmembrane transport 231571 231571 'Rpap2' mRNA 446 464 428.45 10.4 10.78 10.58 6.53 6.96 6.73 10.58666667 6.74 316 336 320 446.15 324 3.67E-04 -0.471518602 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016591///RNA polymerase II, holoenzyme" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0043175///RNA polymerase core enzyme binding+++GO:0046872///metal ion binding GO:0009301///snRNA transcription+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain 231580 231580 'Gak' mRNA 1940 2051 2159 23.05 23.93 27.1 26.38 24.97 25.43 24.69333333 25.59333333 2501 2295 2322 2050 2372.666667 0.022839828 0.195779996 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030276///clathrin binding+++GO:0030332///cyclin binding GO:0006468///protein phosphorylation+++GO:0006898///receptor-mediated endocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0009913///epidermal cell differentiation+++GO:0010977///negative regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0034067///protein localization to Golgi apparatus+++GO:0035622///intrahepatic bile duct development+++GO:0048468///cell development+++GO:0048853///forebrain morphogenesis+++GO:0061436///establishment of skin barrier+++GO:0072318///clathrin coat disassembly+++GO:0072583///clathrin-dependent endocytosis+++GO:0072659///protein localization to plasma membrane+++GO:0090160///Golgi to lysosome transport+++GO:1905224///clathrin-coated pit assembly+++GO:2000179///positive regulation of neural precursor cell proliferation 231583 231583 'Slc26a1' mRNA 34.87 50.05 26.02 0.52 0.7 0.39 0.39 0.44 0.7 0.536666667 0.51 34 35.06 53.09 36.98 40.71666667 0.800369356 0.148553142 05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane "GO:0004145///diamine N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019531///oxalate transmembrane transporter activity+++GO:0019809///spermidine binding+++GO:0042802///identical protein binding" GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0006598///polyamine catabolic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0008272///sulfate transport+++GO:0009447///putrescine catabolic process+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0032918///spermidine acetylation+++GO:0042127///regulation of cell proliferation+++GO:0046208///spermine catabolic process+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 231600 231600 'Chfr' mRNA 640 548 596 11.02 9.31 10.94 12.23 11.97 12.63 10.42333333 12.27666667 817 780 819 594.6666667 805.3333333 1.20E-04 0.424385508 GO:0005634///nucleus+++GO:0016605///PML body GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0000278///mitotic cell cycle+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0044779///meiotic spindle checkpoint+++GO:0044818///mitotic G2/M transition checkpoint+++GO:0051301///cell division 231602 231602 'P2rx2' mRNA 7653 7483 7459 237.54 227.01 244.27 222.36 237.05 223.76 236.2733333 227.7233333 8293 8591 8127 7531.666667 8337 0.032810651 0.134534299 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04742///Taste transduction GO:0005622///intracellular+++GO:0005639///integral component of nuclear inner membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0042734///presynaptic membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043235///receptor complex+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane "GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0005507///copper ion binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0015276///ligand-gated ion channel activity+++GO:0016151///nickel cation binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0043924///suramin binding+++GO:0044877///protein-containing complex binding+++GO:0045340///mercury ion binding+++GO:0046870///cadmium ion binding+++GO:0050897///cobalt ion binding" GO:0001666///response to hypoxia+++GO:0002931///response to ischemia+++GO:0003029///detection of hypoxic conditions in blood by carotid body chemoreceptor signaling+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0007605///sensory perception of sound+++GO:0009743///response to carbohydrate+++GO:0010033///response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0019228///neuronal action potential+++GO:0030432///peristalsis+++GO:0033198///response to ATP+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048266///behavioral response to pain+++GO:0048741///skeletal muscle fiber development+++GO:0050909///sensory perception of taste+++GO:0060079///excitatory postsynaptic potential+++GO:0098655///cation transmembrane transport+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 231605 231605 'Galnt9' mRNA 59 68 14 1.35 1.27 0.52 0.88 0.97 1.22 1.046666667 1.023333333 27 30 38 47 31.66666667 0.345011498 -0.555102005 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0030246///carbohydrate binding GO:0006486///protein glycosylation+++GO:0008150///biological_process 231630 231630 'Ficd' mRNA 672 647 636 11.64 10.99 11.67 8.26 8.15 8.03 11.43333333 8.146666667 549 529 517 651.6666667 531.6666667 0.006248431 -0.305625008 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0030544///Hsp70 protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044603///protein adenylylhydrolase activity+++GO:0051087///chaperone binding+++GO:0070733///protein adenylyltransferase activity GO:0006986///response to unfolded protein+++GO:0018117///protein adenylylation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0044602///protein deadenylylation+++GO:1903894///regulation of IRE1-mediated unfolded protein response 231633 231633 'Tmem119' mRNA 282 289 221 7.46 7.59 6.23 18.95 20.18 17.25 7.093333333 18.79333333 818 852 723 264 797.6666667 8.07E-37 1.587953287 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001958///endochondral ossification+++GO:0007283///spermatogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010832///negative regulation of myotube differentiation+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045779///negative regulation of bone resorption+++GO:0048515///spermatid differentiation+++GO:1903012///positive regulation of bone development 231637 231637 'Ssh1' mRNA 723 691 740 4.55 4.28 4.95 4.83 4.13 4.72 4.593333333 4.56 882 737 836 718 818.3333333 0.144890655 0.173763954 04360///Axon guidance+++04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0031252///cell leading edge+++GO:0032154///cleavage furrow+++GO:0042995///cell projection+++GO:0045202///synapse GO:0003779///actin binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0000902///cell morphogenesis+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032268///regulation of cellular protein metabolic process+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0071318///cellular response to ATP+++GO:0098976///excitatory chemical synaptic transmission+++GO:1901216///positive regulation of neuron death+++GO:1904719///positive regulation of AMPA glutamate receptor clustering+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:2000463///positive regulation of excitatory postsynaptic potential 231642 231642 'Alkbh2' mRNA 120 155 176.25 8.38 10.51 12.62 11.07 15.1 11.69 10.50333333 12.62 188 247.83 198 150.4166667 211.2766667 0.042657663 0.474150831 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0035516///oxidative DNA demethylase activity+++GO:0043734///DNA-N1-methyladenine dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051747///cytosine C-5 DNA demethylase activity+++GO:0103053///1-ethyladenine demethylase activity" GO:0006281///DNA repair+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0035511///oxidative DNA demethylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 231646 231646 'Myo1h' mRNA 1403.83 1458.1 1333.62 16.79 17.1 17.12 2.15 1.52 1.58 17.00333333 1.75 183.4 130.02 131.79 1398.516667 148.4033333 1.90E-160 -3.252572239 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0031982///vesicle GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0030050///vesicle transport along actin filament 231655 231655 'Oasl1' mRNA 101 96 114 2.61 2.42 3.39 26.78 26.95 25.79 2.806666667 26.50666667 1161 1159 1105 103.6666667 1141.666667 2.72E-155 3.447900052 05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0016779///nucleotidyltransferase activity GO:0002376///immune system process+++GO:0009615///response to virus+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060700///regulation of ribonuclease activity+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:1900246///positive regulation of RIG-I signaling pathway 231659 231659 'Gcn1' mRNA 1154 1187 1079 7.09 7.17 7.03 6.68 6.04 6.48 7.096666667 6.4 1252 1105 1176 1140 1177.666667 0.754095254 0.035385246 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome GO:0005515///protein binding+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0043022///ribosome binding GO:0006417///regulation of translation+++GO:0033674///positive regulation of kinase activity+++GO:0034198///cellular response to amino acid starvation+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:1990253///cellular response to leucine starvation 231668 231668 'Vsig10' mRNA 570 491 364 7.58 6.43 5.14 4.61 5.85 6.06 6.383333333 5.506666667 399 494 508 475 467 0.89548485 -0.027032806 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0003674///molecular_function GO:0008150///biological_process 231670 231670 'Fbxo21' mRNA 2318 2386 2328 32.11 32.52 34.21 20.05 17.07 17.8 32.94666667 18.30666667 1666 1385 1432 2344 1494.333333 4.66E-17 -0.663408257 GO:0005575///cellular_component GO:0003677///DNA binding GO:0008150///biological_process 231672 231672 'Fbxw8' mRNA 676 665 675 7.26 7.02 7.69 6.35 6.83 6.5 7.323333333 6.56 681 716 675 672 690.6666667 0.863090843 0.027384874 04120///Ubiquitin mediated proteolysis "GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030687///preribosome, large subunit precursor+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:1990393///3M complex" GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007030///Golgi organization+++GO:0008283///cell proliferation+++GO:0016567///protein ubiquitination+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0060712///spongiotrophoblast layer development+++GO:0060716///labyrinthine layer blood vessel development+++GO:1901485///positive regulation of transcription factor catabolic process 231691 231691 'Sds' mRNA 0 1 0 0 0.05 0 0 0.05 0 0.016666667 0.016666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++00290///Valine, leucine and isoleucine biosynthesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003941///L-serine ammonia-lyase activity+++GO:0004794///L-threonine ammonia-lyase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042803///protein homodimerization activity GO:0006094///gluconeogenesis+++GO:0006520///cellular amino acid metabolic process+++GO:0006565///L-serine catabolic process+++GO:0006567///threonine catabolic process+++GO:0009097///isoleucine biosynthetic process+++GO:0042866///pyruvate biosynthetic process+++GO:0065003///protein-containing complex assembly 231699 231699 'Oas1e' mRNA 2 0 0 0.08 0 0 0.06 0.15 0 0.026666667 0.07 2 5 0 0.666666667 2.333333333 0.529127799 1.822280999 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0016779///nucleotidyltransferase activity GO:0006006///glucose metabolic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 231712 231712 'Trafd1' mRNA 1685 1687 1605 37.75 37.19 38.34 57.39 55.85 58.71 37.76 57.31666667 2936 2791 2922 1659 2883 5.65E-34 0.785643684 GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0045824///negative regulation of innate immune response 231713 231713 'Naa25' mRNA 916 829 799 9.04 8.05 8.37 7.26 7.86 8.09 8.486666667 7.736666667 848 895 914 848 885.6666667 0.689939438 0.05253528 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0031416///NatB complex GO:0004596///peptide alpha-N-acetyltransferase activity GO:0017196///N-terminal peptidyl-methionine acetylation 231717 231717 'Pheta1' mRNA 495 514 524 11.82 12.03 13.24 8.65 6.97 7.23 12.36333333 7.616666667 418 330 336 511 361.3333333 1.68E-04 -0.515276583 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome GO:0042803///protein homodimerization activity "GO:0001881///receptor recycling+++GO:0007032///endosome organization+++GO:0042147///retrograde transport, endosome to Golgi" 231724 231724 'Rad9b' mRNA 198.65 236.73 264.51 4.05 4.77 5.32 2.09 1.75 1.72 4.713333333 1.853333333 121.04 93.73 93.52 233.2966667 102.7633333 2.25E-08 -1.203844621 04218///Cellular senescence GO:0005634///nucleus+++GO:0030896///checkpoint clamp complex GO:0008408///3'-5' exonuclease activity GO:0000076///DNA replication checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0031573///intra-S DNA damage checkpoint+++GO:0071479///cellular response to ionizing radiation 231727 231727 'B3gnt4' mRNA 192.2 165.68 180.96 5.26 4.7 5.45 1 1.41 1.22 5.136666667 1.21 41.28 50.58 40.39 179.6133333 44.08333333 2.38E-16 -2.047512351 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008457///beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 231760 231760 'Rimbp2' mRNA 407 381 250 3.39 3.25 2.3 0.3 0.37 0.3 2.98 0.323333333 39 47 38 346 41.33333333 2.39E-40 -3.067317947 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098831///presynaptic active zone cytoplasmic component GO:0007274///neuromuscular synaptic transmission+++GO:0010923///negative regulation of phosphatase activity 231769 231769 'Sfswap' mRNA 1305 1243 628 14.17 13.14 8.59 6.86 7.34 7.95 11.96666667 7.383333333 588 647 683 1058.666667 639.3333333 0.028699217 -0.722781933 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000395///mRNA 5'-splice site recognition+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 231798 231798 'Lrch4' mRNA 6973 6877 6030 124.96 121.08 114.46 72.65 74.03 67.16 120.1666667 71.28 4345 4324 3854 6626.666667 4174.333333 1.04E-26 -0.676206388 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body GO:0005515///protein binding "GO:0045892///negative regulation of transcription, DNA-templated" 231801 231801 'Agfg2' mRNA 1568 1626 1550 29.45 30.03 30.86 23.49 22.84 23.2 30.11333333 23.17666667 1436 1365 1375 1581.333333 1392 0.013860017 -0.196035954 GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 231803 231803 'Mepce' mRNA 502 444 441 8.68 7.55 8.09 5.75 5.89 5.62 8.106666667 5.753333333 383 383 362 462.3333333 376 0.021816401 -0.309483231 GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0017069///snRNA binding+++GO:0097322///7SK snRNA binding+++GO:1990276///RNA 5'-methyltransferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001510///RNA methylation+++GO:0016073///snRNA metabolic process+++GO:0032259///methylation+++GO:0035562///negative regulation of chromatin binding+++GO:0040031///snRNA modification+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1905382///positive regulation of snRNA transcription by RNA polymerase II 231805 231805 'Pilra' mRNA 19.96 20.62 12.97 0.43 0.44 0.3 8.34 8.73 9.65 0.39 8.906666667 446.66 457.02 500.47 17.85 468.05 4.03E-79 4.773872429 05168///Herpes simplex virus 1 infection GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0042288///MHC class I protein binding GO:0007165///signal transduction 231807 231807 'Map11' mRNA 121 108 37 2.64 2.32 0.86 1.54 2.26 2.28 1.94 2.026666667 81 116 116 88.66666667 104.3333333 0.582145645 0.245891634 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030496///midbody+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072686///mitotic spindle+++GO:1990071///TRAPPII protein complex GO:0043014///alpha-tubulin binding GO:0030030///cell projection organization+++GO:0042127///regulation of cell proliferation+++GO:0060271///cilium assembly 231821 231821 'Adap1' mRNA 143 144 139 3.33 3.3 3.44 3.47 3.32 3.22 3.356666667 3.336666667 171 160 154 142 161.6666667 0.466525661 0.174958082 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity 231830 231830 'Micall2' mRNA 82 116 72 1.34 1.86 1.25 1.67 1.74 1.56 1.483333333 1.656666667 114 117 103 90 111.3333333 0.31554991 0.30185898 04530///Tight junction GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032432///actin filament bundle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0031267///small GTPase binding+++GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0030041///actin filament polymerization+++GO:0031175///neuron projection development+++GO:0031532///actin cytoskeleton reorganization+++GO:0032456///endocytic recycling+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0070830///bicellular tight junction assembly 231832 231832 'Tmem184a' mRNA 1494 1447 1523 42.39 40.24 45.87 23.02 24.48 26.98 42.83333333 24.82666667 927 944 1032 1488 967.6666667 4.12E-12 -0.633860619 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005215///transporter activity+++GO:0008201///heparin binding GO:0006810///transport+++GO:0018992///germ-line sex determination+++GO:0032880///regulation of protein localization+++GO:0051046///regulation of secretion 231834 231834 'Snx8' mRNA 570.4 541 551 11.67 10.96 11.94 24.22 24.55 26.09 11.52333333 24.95333333 1360 1336.98 1409.29 554.1333333 1368.756667 3.51E-46 1.292350604 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding "GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0034498///early endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi" 231841 231841 'Brat1' mRNA 638 709 633 10.3 11.26 10.87 10.21 11.06 10.61 10.81 10.62666667 729 771 736 660 745.3333333 0.150255044 0.16519438 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0001934///positive regulation of protein phosphorylation+++GO:0006006///glucose metabolic process+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0010212///response to ionizing radiation+++GO:0016477///cell migration+++GO:0030307///positive regulation of cell growth+++GO:0051646///mitochondrion localization 231842 231842 'Amz1' mRNA 108 104 116 2.23 2.11 2.54 4.34 4.68 4.91 2.293333333 4.643333333 242 255 265 109.3333333 254 2.04E-10 1.202974529 GO:0005575///cellular_component GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 231855 231855 'Ap5z1' mRNA 440.36 458.26 443.78 5.88 5.95 6.27 6.07 6.38 7.07 6.033333333 6.506666667 518 533.75 591.13 447.4666667 547.6266667 0.029399327 0.280768681 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0044599///AP-5 adaptor complex GO:0003674///molecular_function GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0015031///protein transport+++GO:0016197///endosomal transport 231858 231858 'Radil' mRNA 777 788 755 11.53 11.44 11.87 3.39 3.72 3.52 11.61333333 3.543333333 266 285 268 773.3333333 273 1.09E-39 -1.513385001 GO:0005874///microtubule+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0051020///GTPase binding GO:0001755///neural crest cell migration+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0034446///substrate adhesion-dependent cell spreading 231861 231861 'Tnrc18' mRNA 1555 1531 1065.98 7.16 7.39 5.23 5.02 4.58 5.09 6.593333333 4.896666667 1232 1083.99 1222 1383.993333 1179.33 0.047714231 -0.235941814 GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0003682///chromatin binding GO:0008150///biological_process 231863 231863 'Fbxl18' mRNA 320.97 283.66 217.1 3.1 2.68 2.64 3.24 2.97 3.49 2.806666667 3.233333333 311.38 264.05 314.78 273.91 296.7366667 0.607707351 0.109468726 GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 231866 231866 'Zfp12' mRNA 421.64 431.45 270.79 4.83 4.71 3.38 2.49 2.32 2.86 4.306666667 2.556666667 252.42 231.9 288.64 374.6266667 257.6533333 0.002705063 -0.544092383 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 231868 231868 'E130309D02Rik' mRNA 337 363 136 8.06 8.6 3.46 4.4 8.29 7.3 6.706666667 6.663333333 210 388 336 278.6666667 311.3333333 0.800528149 0.174271232 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 231871 231871 'Daglb' mRNA 1034 1060 1085 17.86 17.68 19.44 24.27 23.69 22.48 18.32666667 23.48 1646 1562 1484 1059.666667 1564 1.46E-10 0.547953667 04723///Retrograde endocannabinoid signaling+++04745///Phototransduction - fly+++04925///Aldosterone synthesis and secretion GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane GO:0004806///triglyceride lipase activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007405///neuroblast proliferation+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0022008///neurogenesis+++GO:0042136///neurotransmitter biosynthetic process+++GO:0050727///regulation of inflammatory response+++GO:0071926///endocannabinoid signaling pathway+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid 231872 231872 'Aimp2' mRNA 500 539 501 26.6 28.33 28.45 35.89 36.74 35.84 27.79333333 36.15666667 774 761 734 513.3333333 756.3333333 1.79E-07 0.547657562 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0005515///protein binding+++GO:0060090///molecular adaptor activity GO:0006412///translation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0060510///type II pneumocyte differentiation+++GO:0065003///protein-containing complex assembly+++GO:1901216///positive regulation of neuron death+++GO:1903632///positive regulation of aminoacyl-tRNA ligase activity 231874 231874 'Ccz1' mRNA 308 300 233 9.96 9.52 8.02 10.36 10.52 9.58 9.166666667 10.15333333 368 364 330 280.3333333 354 0.038081887 0.329263474 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0035658///Mon1-Ccz1 complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005085///guanyl-nucleotide exchange factor activity GO:0016192///vesicle-mediated transport+++GO:0050790///regulation of catalytic activity 231876 231876 'Lmtk2' mRNA 386 391 344 2.48 2.47 2.34 2.31 1.8 2.55 2.43 2.22 414 315 444 373.6666667 391 0.795197175 0.054060472 GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0070853///myosin VI binding GO:0001881///receptor recycling+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032456///endocytic recycling+++GO:0033572///transferrin transport+++GO:0033674///positive regulation of kinase activity+++GO:0043086///negative regulation of catalytic activity+++GO:0045022///early endosome to late endosome transport+++GO:0046777///protein autophosphorylation+++GO:0048011///neurotrophin TRK receptor signaling pathway 231887 231887 'Pdap1' mRNA 491 466 359 12.98 12.13 10.07 14.2 12.43 13.96 11.72666667 13.53 618 528 588 438.6666667 578 0.003228709 0.390123143 GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0048407///platelet-derived growth factor binding GO:0048008///platelet-derived growth factor receptor signaling pathway 231889 231889 'Bud31' mRNA 741.53 810.64 800.96 57.81 62.73 66.27 86.85 87.44 87.85 62.27 87.38 1275.37 1250.85 1244.48 784.3766667 1256.9 1.86E-13 0.668045435 03040///Spliceosome GO:0000785///chromatin+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome GO:0003674///molecular_function+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035257///nuclear hormone receptor binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000825///positive regulation of androgen receptor activity" 231912 231912 'Katnal1' mRNA 597 501 453 5.04 4.13 4.06 2.4 2.29 2.54 4.41 2.41 324 305 338 517 322.3333333 3.91E-07 -0.690670188 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0007283///spermatogenesis+++GO:0031122///cytoplasmic microtubule organization+++GO:0051013///microtubule severing 231915 231915 'Uspl1' mRNA 873 868 880 13.89 13.24 14.66 11.14 10.75 10.61 13.93 10.83333333 827 785 752 873.6666667 788 0.130214976 -0.162057694 GO:0005634///nucleus+++GO:0015030///Cajal body GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0032183///SUMO binding+++GO:0070140///SUMO-specific isopeptidase activity GO:0001825///blastocyst formation+++GO:0006508///proteolysis+++GO:0008283///cell proliferation+++GO:0009301///snRNA transcription+++GO:0016926///protein desumoylation+++GO:0030576///Cajal body organization 231931 231931 'Gimap6' mRNA 127 189 142 4.61 6.76 5.46 14.84 16.43 13.61 5.61 14.96 470 508 417 152.6666667 465 2.05E-21 1.598223318 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0008150///biological_process 231932 231932 'Gimap7' mRNA 2 0 1 0.1 0 0.05 0.46 0.6 0.56 0.05 0.54 11 14 13 1 12.66666667 0.003843951 3.651690514 GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0046039///GTP metabolic process 231946 231946 'Fam221a' mRNA 27 20 27 0.96 0.7 1.17 1.12 1.2 1.85 0.943333333 1.39 38 32 51 24.66666667 40.33333333 0.156323866 0.693508917 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 231986 231986 'Jazf1' mRNA 221 254 248 4.16 4.76 5.02 1.89 1.82 1.56 4.646666667 1.756666667 108 104 93 241 101.6666667 1.07E-10 -1.258644997 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process 231991 231991 'Creb5' mRNA 148 119 122 2.35 1.73 2.18 2.54 2.47 2.97 2.086666667 2.66 212 204 232 129.6666667 216 2.52E-04 0.725186622 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050872///white fat cell differentiation+++GO:0060612///adipose tissue development" 231997 231997 'Fkbp14' mRNA 924 1001 936 19.01 20.28 20.43 20.39 21.72 19.46 19.90666667 20.52333333 1140 1186 1053 953.6666667 1126.333333 0.019339754 0.228748463 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005509///calcium ion binding+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0000413///protein peptidyl-prolyl isomerization 231999 231999 'Plekha8' mRNA 172 180 195 1.38 1.39 1.66 1.66 1.35 1.42 1.476666667 1.476666667 240 191 200 182.3333333 210.3333333 0.389941226 0.189816502 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008289///lipid binding+++GO:0017089///glycolipid transporter activity+++GO:0051861///glycolipid binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0097001///ceramide binding+++GO:0120013///intermembrane lipid transfer activity+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0006869///lipid transport+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0046836///glycolipid transport+++GO:0120009///intermembrane lipid transfer+++GO:1902389///ceramide 1-phosphate transport 232016 232016 'Itprid1' mRNA 3 2 6 0.05 0.03 0.11 0.16 0.16 0.14 0.063333333 0.153333333 12 12 11 3.666666667 11.66666667 0.10005601 1.642432802 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005102///signaling receptor binding GO:0008150///biological_process 232023 232023 'Vopp1' mRNA 783 821 726 14.74 15.4 14.87 14.84 13.86 14.65 15.00333333 14.45 895 842 860 776.6666667 865.6666667 0.157588545 0.145949955 GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031301///integral component of organelle membrane+++GO:0031410///cytoplasmic vesicle 232035 232035 'Ccser1' mRNA 999.45 1036.14 836.98 7.31 7.85 5.92 1.7 1.58 1.62 7.026666667 1.633333333 266.89 215.88 231.63 957.5233333 238.1333333 2.41E-66 -2.020969677 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 232078 232078 'Thnsl2' mRNA 246 241 226 6.92 6.67 6.74 6.92 6.69 5.07 6.776666667 6.226666667 283 267 201 237.6666667 250.3333333 0.797251951 0.063028741 GO:0004795///threonine synthase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0070905///serine binding GO:0009071///serine family amino acid catabolic process+++GO:0009088///threonine biosynthetic process+++GO:0016311///dephosphorylation+++GO:0046360///2-oxobutyrate biosynthetic process 232086 232086 'Tmem150a' mRNA 245 234 117 9.58 9.02 4.85 10.18 14.65 12.7 7.816666667 12.51 299 420 361 198.6666667 360 1.39E-04 0.862598006 GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009056///catabolic process+++GO:0010506///regulation of autophagy+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 232087 232087 'Mat2a' mRNA 7808 8139 8109 143.55 147.15 157.89 154.95 148.4 150.27 149.53 151.2066667 9660 9013 9018 8018.666667 9230.333333 0.001906962 0.189373877 00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids+++01240///Biosynthesis of cofactors GO:0005829///cytosol+++GO:0048269///methionine adenosyltransferase complex GO:0000166///nucleotide binding+++GO:0004478///methionine adenosyltransferase activity+++GO:0005524///ATP binding+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006556///S-adenosylmethionine biosynthetic process+++GO:0006730///one-carbon metabolic process+++GO:0007623///circadian rhythm+++GO:0009410///response to xenobiotic stimulus+++GO:0009725///response to hormone+++GO:0034214///protein hexamerization+++GO:0042493///response to drug+++GO:0051291///protein heterooligomerization+++GO:0051591///response to cAMP+++GO:1990830///cellular response to leukemia inhibitory factor 232089 232089 'Elmod3' mRNA 834 955 872 21.06 23.51 23.09 16.74 18.48 16.18 22.55333333 17.13333333 773 825 716 887 771.3333333 0.058306267 -0.212635516 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0060091///kinocilium GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0008150///biological_process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 232146 232146 'Eva1a' mRNA 262 314 281 8.5 10.41 9.73 8.8 7.87 9.28 9.546666667 8.65 310 271 317 285.6666667 299.3333333 0.796598969 0.055325023 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0008150///biological_process 232156 232156 'Slc4a5' mRNA 32 17 15 0.33 0.17 0.17 0.06 0.11 0.17 0.223333333 0.113333333 7 12 18 21.33333333 12.33333333 0.282936538 -0.790896062 04976///Bile secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0022857///transmembrane transporter activity GO:0002064///epithelial cell development+++GO:0003014///renal system process+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0010468///regulation of gene expression+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0033326///cerebrospinal fluid secretion+++GO:0035725///sodium ion transmembrane transport+++GO:0048311///mitochondrion distribution+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0060041///retina development in camera-type eye+++GO:0098656///anion transmembrane transport 232157 232157 'Mob1a' mRNA 964 1048 994 17.65 18.27 18.57 36.7 29.29 31.08 18.16333333 32.35666667 2337 1860 1935 1002 2044 3.11E-29 1.014347294 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0035329///hippo signaling 232164 232164 'Paip2b' mRNA 393 461 422 6.45 7.44 7.34 4.69 4.22 4.33 7.076666667 4.413333333 329 289 294 425.3333333 304 4.21E-04 -0.497244318 GO:0005737///cytoplasm "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0008143///poly(A) binding+++GO:0030371///translation repressor activity" GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0045947///negative regulation of translational initiation 232174 232174 'Cyp26b1' mRNA 367 376 258 3.68 3.66 2.82 1.46 1.39 1.13 3.386666667 1.326666667 180 169 147 333.6666667 165.3333333 9.63E-09 -1.01834154 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0001972///retinoic acid binding+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0001709///cell fate determination+++GO:0001768///establishment of T cell polarity+++GO:0001822///kidney development+++GO:0006805///xenobiotic metabolic process+++GO:0006954///inflammatory response+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0009954///proximal/distal pattern formation+++GO:0010628///positive regulation of gene expression+++GO:0016125///sterol metabolic process+++GO:0030326///embryonic limb morphogenesis+++GO:0032526///response to retinoic acid+++GO:0033189///response to vitamin A+++GO:0034653///retinoic acid catabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0043587///tongue morphogenesis+++GO:0045580///regulation of T cell differentiation+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048385///regulation of retinoic acid receptor signaling pathway+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0060349///bone morphogenesis+++GO:0061436///establishment of skin barrier+++GO:0070268///cornification+++GO:0071300///cellular response to retinoic acid+++GO:2001037///positive regulation of tongue muscle cell differentiation 232187 232187 'Smyd5' mRNA 595 594 608 13.3 13.07 14.42 11.76 10.95 9.98 13.59666667 10.89666667 605 550 497 599 550.6666667 0.323423558 -0.135336369 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0046872///metal ion binding "GO:0010529///negative regulation of transposition+++GO:0032259///methylation+++GO:0034773///histone H4-K20 trimethylation+++GO:0034968///histone lysine methylation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:2000035///regulation of stem cell division+++GO:2000736///regulation of stem cell differentiation" 232196 232196 'C87436' mRNA 918.34 860.04 899.98 17.18 15.85 17.66 9.91 9.89 9.54 16.89666667 9.78 627.85 610.47 572.08 892.7866667 603.4666667 1.77E-08 -0.57864909 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 232201 232201 'Arhgap25' mRNA 56 51 63 1.09 0.91 1.26 11.14 10.49 9.62 1.086666667 10.41666667 674 606 574 56.66666667 618 9.03E-89 3.432608025 GO:0001891///phagocytic cup GO:0005096///GTPase activator activity "GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity" 232210 232210 'Hmces' mRNA 510 475 477 21.62 19.87 21.45 14.76 16.42 17.82 20.98 16.33333333 400 434 467 487.3333333 433.6666667 0.213153356 -0.179298899 GO:0005657///replication fork+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0018142///protein-DNA covalent cross-linking+++GO:0045830///positive regulation of isotype switching+++GO:0097681///double-strand break repair via alternative nonhomologous end joining 232223 232223 'Txnrd3' mRNA 308 301 290 5.99 5.76 5.98 4.23 3.91 4.1 5.91 4.08 250 226 235 299.6666667 237 0.028657913 -0.350570047 00450///Selenocompound metabolism+++05200///Pathways in cancer+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0097573///glutathione oxidoreductase activity" GO:0001825///blastocyst formation+++GO:0006749///glutathione metabolic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification 232227 232227 'Iqsec1' mRNA 1120.17 1167.83 819.25 10.87 11.11 8.72 6.89 6.46 7.64 10.23333333 6.996666667 877.55 774.05 875.01 1035.75 842.2033333 0.010005258 -0.303917172 04144///Endocytosis "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding GO:0030036///actin cytoskeleton organization+++GO:0032012///regulation of ARF protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0051549///positive regulation of keratinocyte migration+++GO:0060996///dendritic spine development+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0120183///positive regulation of focal adhesion disassembly 232232 232232 'Hdac11' mRNA 784 900 627 17.78 20.18 15.17 9.91 9.51 10.52 17.71 9.98 495 475 511 770.3333333 493.6666667 1.11E-07 -0.647577213 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific) GO:0006325///chromatin organization+++GO:0014003///oligodendrocyte development+++GO:0016575///histone deacetylation+++GO:0070932///histone H3 deacetylation 232236 232236 'Ccdc174' mRNA 285 331 407 9.28 10.54 14.05 11.11 10.32 10.09 11.29 10.50666667 392 355 344 341 363.6666667 0.749855753 0.073165813 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 232237 232237 'Fgd5' mRNA 93 107 101 0.82 0.93 0.95 1.01 0.76 0.94 0.9 0.903333333 132 97 119 100.3333333 116 0.514125782 0.195008347 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding GO:0050790///regulation of catalytic activity 232286 232286 'Tmf1' mRNA 2563 2411 2299 19.94 18.43 18.99 9.21 8.47 9.22 19.12 8.966666667 1365 1224 1325 2424.333333 1304.666667 3.75E-36 -0.905576471 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0050681///androgen receptor binding GO:0001675///acrosome assembly+++GO:0001819///positive regulation of cytokine production+++GO:0007286///spermatid development+++GO:0007289///spermatid nucleus differentiation+++GO:0008584///male gonad development+++GO:0010629///negative regulation of gene expression+++GO:0030317///flagellated sperm motility+++GO:0030521///androgen receptor signaling pathway+++GO:0032275///luteinizing hormone secretion+++GO:0033327///Leydig cell differentiation+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0071407///cellular response to organic cyclic compound+++GO:2000845///positive regulation of testosterone secretion 232288 232288 'Frmd4b' mRNA 3949 4043 3949 48.64 49.35 52.46 16.25 17.36 17.84 50.15 17.15 1608 1647 1704 3980.333333 1653 8.46E-82 -1.279709002 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction GO:0005515///protein binding GO:0090162///establishment of epithelial cell polarity 232313 232313 'Gxylt2' mRNA 209.78 192.14 211.4 1.58 1.44 1.78 1.08 1.12 0.93 1.6 1.043333333 160.97 156.37 139.49 204.44 152.2766667 0.027557475 -0.441728855 00514///Other types of O-glycan biosynthesis GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035252///UDP-xylosyltransferase activity" GO:0016266///O-glycan processing 232314 232314 'Ppp4r2' mRNA 598 590.57 580 7.29 7.04 7.64 7.57 6.18 8.16 7.323333333 7.303333333 662.54 542 684 589.5233333 629.5133333 0.588015157 0.081559115 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030289///protein phosphatase 4 complex "GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0006470///protein dephosphorylation+++GO:0008380///RNA splicing+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0050790///regulation of catalytic activity 232333 232333 'Slc6a1' mRNA 854 986 789 10.45 11.87 10.28 9.65 8.76 9.46 10.86666667 9.29 897 796 851 876.3333333 848 0.66379506 -0.056953204 04721///Synaptic vesicle cycle+++04727///GABAergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005332///gamma-aminobutyric acid:sodium symporter activity+++GO:0015185///gamma-aminobutyric acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015378///sodium:chloride symporter activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006836///neurotransmitter transport+++GO:0007612///learning+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0009636///response to toxic substance+++GO:0009744///response to sucrose+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0010243///response to organonitrogen compound+++GO:0010288///response to lead ion+++GO:0014054///positive regulation of gamma-aminobutyric acid secretion+++GO:0014070///response to organic cyclic compound+++GO:0014074///response to purine-containing compound+++GO:0015812///gamma-aminobutyric acid transport+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0032355///response to estradiol+++GO:0035725///sodium ion transmembrane transport+++GO:0042220///response to cocaine+++GO:0050808///synapse organization+++GO:0051592///response to calcium ion+++GO:0051939///gamma-aminobutyric acid import+++GO:0055085///transmembrane transport+++GO:0098658///inorganic anion import across plasma membrane+++GO:0098719///sodium ion import across plasma membrane+++GO:0098810///neurotransmitter reuptake+++GO:1902476///chloride transmembrane transport" 232334 232334 'Vgll4' mRNA 2023.58 1948.49 1737.35 27.6 26.4 24.66 24.14 20.47 22.49 26.22 22.36666667 1899.77 1562 1689.77 1903.14 1717.18 0.068605164 -0.159661678 GO:0005634///nucleus GO:0001223///transcription coactivator binding+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0035331///negative regulation of hippo signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:1903364///positive regulation of cellular protein catabolic process" 232337 232337 'Zfp637' mRNA 1348 1368 1311 69.38 69.45 71.17 67.3 69.39 70.23 70 68.97333333 1495 1508 1501 1342.333333 1501.333333 0.073613892 0.150068834 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 232339 232339 'Ankrd26' mRNA 751 806 753 7.41 8.02 7.89 3.81 3.95 3.51 7.773333333 3.756666667 429 432 370 770 410.3333333 2.93E-16 -0.919738133 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0005515///protein binding GO:0019216///regulation of lipid metabolic process+++GO:0019217///regulation of fatty acid metabolic process+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042593///glucose homeostasis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0046621///negative regulation of organ growth+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0060259///regulation of feeding behavior+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 232341 232341 'Wnk1' mRNA 1677 1595 1226 8.44 7.85 6.59 9.02 8.13 9.26 7.626666667 8.803333333 2053 1814 2047 1499.333333 1971.333333 4.48E-05 0.387843635 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019870///potassium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0030295///protein kinase activator activity GO:0002028///regulation of sodium ion transport+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006468///protein phosphorylation+++GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0010766///negative regulation of sodium ion transport+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0010923///negative regulation of phosphatase activity+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0033633///negative regulation of cell-cell adhesion mediated by integrin+++GO:0033673///negative regulation of kinase activity+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0034260///negative regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0050794///regulation of cellular process+++GO:0050801///ion homeostasis+++GO:0050852///T cell receptor signaling pathway+++GO:0071277///cellular response to calcium ion+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097022///lymphocyte migration into lymph node+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:1903288///positive regulation of potassium ion import+++GO:1904062///regulation of cation transmembrane transport+++GO:1990869///cellular response to chemokine+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 232345 232345 'A2m' mRNA 785 810 829 9 9.14 10.09 10.29 9.77 9.54 9.41 9.866666667 1033 958 927 808 972.6666667 0.012898695 0.253717996 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0019899///enzyme binding+++GO:0019959///interleukin-8 binding+++GO:0019966///interleukin-1 binding+++GO:0030414///peptidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0043120///tumor necrosis factor binding+++GO:0048306///calcium-dependent protein binding+++GO:0048403///brain-derived neurotrophic factor binding+++GO:0048406///nerve growth factor binding "GO:0001869///negative regulation of complement activation, lectin pathway+++GO:0007565///female pregnancy+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0048863///stem cell differentiation" 232370 232370 'Clstn3' mRNA 790 711 678 10.91 9.6 9.69 1.76 1.49 1.75 10.06666667 1.666666667 141 124 139 726.3333333 134.6666667 1.82E-73 -2.442427274 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding "GO:0001558///regulation of cell growth+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0035249///synaptic transmission, glutamatergic+++GO:0050806///positive regulation of synaptic transmission+++GO:0051932///synaptic transmission, GABAergic+++GO:0051965///positive regulation of synapse assembly+++GO:1902474///positive regulation of protein localization to synapse+++GO:1905606///regulation of presynapse assembly" 232371 232371 'C1rl' mRNA 148 152 127 2.7 2.73 2.46 2.79 3.07 3.1 2.63 2.986666667 176 189 189 142.3333333 184.6666667 0.078258972 0.367379604 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0072562///blood microparticle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0031638///zymogen activation+++GO:0045087///innate immune response" 232400 232400 'A2ml1' mRNA 80 88 51 0.91 0.99 0.62 0.1 0.08 0.05 0.84 0.076666667 10 8 5 73 7.666666667 1.25E-11 -3.254469742 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 232406 232406 'BC035044' mRNA 24 18 19 0.51 0.38 0.43 0.67 0.51 0.73 0.44 0.636666667 36 27 38 20.33333333 33.66666667 0.17279273 0.714773905 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 232408 232408 'Klrb1f' mRNA 5 1 3 0.1 0.01 0.11 0.09 0.19 0.06 0.073333333 0.113333333 4 7 2 3 4.333333333 0.766965774 0.518915391 05144///Malaria GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity 232409 232409 'Clec2e' mRNA 3 0 5 0.07 0 0.13 0.04 0 0.09 0.066666667 0.043333333 2 0 4 2.666666667 2 0.862557547 -0.464292395 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding+++GO:0046703///natural killer cell lectin-like receptor binding GO:0008150///biological_process 232413 232413 'Clec12a' mRNA 89 67 95 2.26 1.67 2.55 30.22 29.6 28.23 2.16 29.35 1371 1311 1240 83.66666667 1307.333333 7.06E-181 3.951541864 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0030545///receptor regulator activity GO:0050776///regulation of immune response 232414 232414 'Clec9a' mRNA 7 2 2 0.13 0.04 0.04 0.16 0.3 0.41 0.07 0.29 11 18 25 3.666666667 18 0.00993789 2.295596153 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0001819///positive regulation of cytokine production+++GO:0006898///receptor-mediated endocytosis 232430 232430 'Crebl2' mRNA 1364 1380.96 1254 17.32 16.91 17.01 10.16 11.4 11.44 17.08 11 868 941.72 936 1332.986667 915.24 1.85E-10 -0.552098357 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046326///positive regulation of glucose import+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0050821///protein stabilization" 232431 232431 'Gprc5a' mRNA 72 64 57 1.97 1.73 1.66 5.79 4.95 6.54 1.786666667 5.76 243 203 266 64.33333333 237.3333333 5.48E-18 1.872880342 GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0070062///extracellular exosome GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity GO:0007165///signal transduction+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032147///activation of protein kinase activity 232440 232440 'H2aj' mRNA 1006 1026 1106 31.68 31.84 36.95 44.71 55.35 49.88 33.49 49.98 1632 1972 1762 1046 1788.666667 8.13E-14 0.7613419 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 232441 232441 'Rerg' mRNA 112 98 91 2.79 2.42 2.41 4.6 4.6 4.17 2.54 4.456666667 212 207 186 100.3333333 201.6666667 1.16E-06 0.996928396 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0030308///negative regulation of cell growth 232449 232449 'Dera' mRNA 505 590 578 17.29 19.68 20.88 17.19 19.02 18.29 19.28333333 18.16666667 582 626 598 557.6666667 602 0.510941208 0.097867324 00030///Pentose phosphate pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004139///deoxyribose-phosphate aldolase activity+++GO:0016829///lyase activity GO:0009264///deoxyribonucleotide catabolic process+++GO:0016052///carbohydrate catabolic process+++GO:0046121///deoxyribonucleoside catabolic process+++GO:0046386///deoxyribose phosphate catabolic process 232491 232491 'Pyroxd1' mRNA 522.95 531.32 487.74 11 10.7 11.52 8.16 7.97 8.17 11.07333333 8.1 423.35 404.2 416.63 514.0033333 414.7266667 0.008951256 -0.320043608 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030017///sarcomere GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0034599///cellular response to oxidative stress 232533 232533 'Stk38l' mRNA 873 814 845 10.52 9.67 10.75 8.45 7.69 7.81 10.31333333 7.983333333 809 720 727 844 752 0.101019854 -0.180181719 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007399///nervous system development+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0051128///regulation of cellular component organization 232536 232536 'Mrps35' mRNA 566 518 566 33.2 29.94 35.48 32.49 30.31 31.39 32.87333333 31.39666667 622 569 593 550 594.6666667 0.486939432 0.098424877 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0008150///biological_process+++GO:0032543///mitochondrial translation 232539 232539 'Klhl42' mRNA 725 655 670 5.37 4.82 5.37 4.42 3.63 3.87 5.186666667 3.973333333 665 534 576 683.3333333 591.6666667 0.074083507 -0.221731528 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0003674///molecular_function+++GO:0004842///ubiquitin-protein transferase activity GO:0000209///protein polyubiquitination+++GO:0007049///cell cycle+++GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0032886///regulation of microtubule-based process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051301///cell division 232560 232560 'Caprin2' mRNA 267 290 233 4.17 4.14 3.7 1.98 1.93 2.11 4.003333333 2.006666667 139 143 149 263.3333333 143.6666667 5.66E-07 -0.882215521 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043235///receptor complex GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0046872///metal ion binding GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0032092///positive regulation of protein binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0040008///regulation of growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway 232566 232566 'Amn1' mRNA 327 329 324 18.65 17.89 19.03 13.02 16.1 17.22 18.52333333 15.44666667 269 321 334 326.6666667 308 0.629348412 -0.095298533 GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 232664 232664 'Ccdc136' mRNA 372 386 323 4.33 4.35 3.84 3.21 2.74 3.07 4.173333333 3.006666667 316 294.75 277 360.3333333 295.9166667 0.049697759 -0.294980192 GO:0002080///acrosomal membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0001675///acrosome assembly+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0030154///cell differentiation 232670 232670 'Tspan33' mRNA 26 38 27 0.74 1.07 0.82 0.3 0.36 0.38 0.876666667 0.346666667 12 14 15 30.33333333 13.66666667 0.038676152 -1.156711746 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0046930///pore complex+++GO:0097197///tetraspanin-enriched microdomain GO:0019899///enzyme binding GO:0046931///pore complex assembly+++GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane 232679 232679 'Zc3hc1' mRNA 447 437 516 14.13 13.64 17.33 13.45 12.58 14.94 15.03333333 13.65666667 488 446 525 466.6666667 486.3333333 0.827079752 0.043081603 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 232680 232680 'Cpa2' mRNA 41 25 28 2.37 1.44 1.81 0.79 1.2 1.1 1.873333333 1.03 15 22 20 31.33333333 19 0.191531282 -0.729294283 04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 232714 232714 'Mgam' mRNA 0 2 0 0 0.02 0 0 0.01 0.01 0.006666667 0.006666667 0 2 2 0.666666667 1.333333333 0.777560031 1.038459353 00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++04973///Carbohydrate digestion and absorption GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0004339///glucan 1,4-alpha-glucosidase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004558///alpha-1,4-glucosidase activity+++GO:0016160///amylase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0032450///maltose alpha-glucosidase activity+++GO:0090599///alpha-glucosidase activity" GO:0000023///maltose metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process 232748 232748 'Tcaf2' mRNA 205 240 177 2.68 3.09 2.5 2.84 3.01 3.07 2.756666667 2.973333333 245 260 262 207.3333333 255.6666667 0.112134364 0.295608349 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction GO:0044325///ion channel binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0010359///regulation of anion channel activity+++GO:0010360///negative regulation of anion channel activity+++GO:0030335///positive regulation of cell migration+++GO:0090314///positive regulation of protein targeting to membrane 232784 232784 'Zfp212' mRNA 556 570 514 11.36 11.46 11.14 8.44 8.17 8.73 11.32 8.446666667 475 449 476 546.6666667 466.6666667 0.048950261 -0.238946712 05168///Herpes simplex virus 1 infection GO:0005654///nucleoplasm GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 232790 232790 'Oscar' mRNA 3 1 1 0.09 0.03 0.03 0.11 0.06 0.06 0.05 0.076666667 4 2 2 1.666666667 2.666666667 0.758641051 0.667420915 04380///Osteoclast differentiation GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038064///collagen receptor activity GO:0030316///osteoclast differentiation+++GO:0032623///interleukin-2 production+++GO:0038065///collagen-activated signaling pathway+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0045780///positive regulation of bone resorption+++GO:0072674///multinuclear osteoclast differentiation 232791 232791 'Cnot3' mRNA 1801.6 1825.44 1607.51 21.38 20.34 18.65 16.98 16.96 14.93 20.12333333 16.29 1565.52 1478.31 1363.61 1744.85 1469.146667 0.00130056 -0.258524954 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex GO:0005515///protein binding "GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0001829///trophectodermal cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0031047///gene silencing by RNA+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:2000036///regulation of stem cell population maintenance" 232798 232798 'Leng8' mRNA 9775 9455 7864 107.76 103.06 92.78 51.41 45.52 48.64 101.2 48.52333333 5207 4551 4816 9031.333333 4858 2.28E-44 -0.903541392 GO:0005634///nucleus GO:0008150///biological_process 232801 232801 'Lilra5' mRNA 46 32 35 1.2 0.81 0.97 2.06 2.36 2.04 0.993333333 2.153333333 90 101 86 37.66666667 92.33333333 6.02E-05 1.283394781 04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0032396///inhibitory MHC class I receptor activity GO:0019221///cytokine-mediated signaling pathway+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032696///negative regulation of interleukin-13 production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0043410///positive regulation of MAPK cascade+++GO:0050729///positive regulation of inflammatory response+++GO:0050867///positive regulation of cell activation+++GO:0051928///positive regulation of calcium ion transport+++GO:0061098///positive regulation of protein tyrosine kinase activity 232807 232807 'Ppp1r12c' mRNA 308 296 314 5.7 5.41 6.25 8.25 7.5 7.92 5.786666667 7.89 508 450 474 306 477.3333333 2.33E-06 0.627415602 04270///Vascular smooth muscle contraction+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0004857///enzyme inhibitor activity+++GO:0019208///phosphatase regulator activity+++GO:0019901///protein kinase binding GO:0007165///signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 232811 232811 'Kmt5c' mRNA 1467 1385 1327 31.35 29.85 33.47 21.83 24.18 22.04 31.55666667 22.68333333 1044 1171 1053 1393 1089.333333 6.06E-05 -0.364815772 00310///Lysine degradation "GO:0000779///condensed chromosome, centromeric region+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin" GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0042393///histone binding+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0046872///metal ion binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0034772///histone H4-K20 dimethylation+++GO:0034773///histone H4-K20 trimethylation+++GO:0045830///positive regulation of isotype switching+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 232813 232813 'Shisa7' mRNA 122 118 88 1.09 1.03 0.83 0.64 0.46 0.75 0.983333333 0.616666667 82 58 93 109.3333333 77.66666667 0.092132259 -0.5011878 "GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0032591///dendritic spine membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0098985///asymmetric, glutamatergic, excitatory synapse+++GO:0099060///integral component of postsynaptic specialization membrane" GO:0005515///protein binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0050811///GABA receptor binding GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007613///memory+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0106040///regulation of GABA-A receptor activity+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1904717///regulation of AMPA glutamate receptor clustering+++GO:2000311///regulation of AMPA receptor activity 232816 232816 'Zfp628' mRNA 92 100 58 1.42 1.55 0.97 0.9 1.46 1.26 1.313333333 1.206666667 67 106 90 83.33333333 87.66666667 0.863090843 0.074775889 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II" 232821 232821 'Ccdc106' mRNA 126 146 136 4.89 5.35 5.28 4.49 4.24 4.2 5.173333333 4.31 127 117 122 136 122 0.527313859 -0.169168006 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 232827 232827 'Nlrp2' mRNA 7 3 1 0.11 0.05 0.02 0 0.01 0.01 0.06 0.006666667 0 1 1 3.666666667 0.666666667 0.251242236 -2.441943112 "GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle" GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0019966///interleukin-1 binding+++GO:0032090///Pyrin domain binding+++GO:0042802///identical protein binding+++GO:0089720///caspase binding GO:0010951///negative regulation of endopeptidase activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 232853 232853 'Zfp954' mRNA 307 282 304 8.56 7.75 9 9.2 7.9 7.62 8.436666667 8.24 379 318 304 297.6666667 333.6666667 0.406941291 0.149778322 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 232854 232854 'Zfp418' mRNA 97 102 110 1.99 2.06 2.39 1.84 1.2 1.49 2.146666667 1.51 103 66 81 103 83.33333333 0.296136084 -0.323517621 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0001933///negative regulation of protein phosphorylation+++GO:0003300///cardiac muscle hypertrophy+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development" 232855 232855 'Zfp772' mRNA 228 197 251 4.54 3.86 5.31 3.26 2.54 3.29 4.57 3.03 188 143 184 225.3333333 171.6666667 0.052228539 -0.41092495 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 232875 232875 'Zscan18' mRNA 280 266 249 4.1 3.79 3.84 0.87 0.97 0.78 3.91 0.873333333 68 75 59 265 67.33333333 7.31E-23 -1.986865979 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 232878 232878 'Zscan22' mRNA 601 606 642 10.99 10.84 12.45 6.5 6.15 5.74 11.42666667 6.13 415 383 362 616.3333333 386.6666667 2.05E-08 -0.687226626 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 232879 232879 'Zbtb45' mRNA 491.81 477.49 320.89 10.08 9.63 6.32 8.34 7.42 8.6 8.676666667 8.12 492.29 422.61 470.64 430.0633333 461.8466667 0.604529298 0.098733203 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development 232889 232889 'Pla2g4c' mRNA 12 21 19 0.18 0.33 0.31 0.42 0.39 0.38 0.273333333 0.396666667 41 30 27 17.33333333 32.66666667 0.102128716 0.897594049 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04217///Necroptosis+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0031966///mitochondrial membrane "GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006663///platelet activating factor biosynthetic process+++GO:0009395///phospholipid catabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0046475///glycerophospholipid catabolic process+++GO:0140042///lipid droplet formation 232906 232906 'Arhgap35' mRNA 2237 2147 1694 14.01 13.28 11.26 8.01 6.97 7.92 12.85 7.633333333 1470 1246 1408 2026 1374.666667 4.85E-10 -0.567491334 04510///Focal adhesion+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005525///GTP binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0032794///GTPase activating protein binding+++GO:0044877///protein-containing complex binding "GO:0001843///neural tube closure+++GO:0007165///signal transduction+++GO:0007229///integrin-mediated signaling pathway+++GO:0007411///axon guidance+++GO:0007413///axonal fasciculation+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0008360///regulation of cell shape+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030879///mammary gland development+++GO:0030900///forebrain development+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0031668///cellular response to extracellular stimulus+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043010///camera-type eye development+++GO:0043116///negative regulation of vascular permeability+++GO:0043547///positive regulation of GTPase activity+++GO:0044319///wound healing, spreading of cells+++GO:0045724///positive regulation of cilium assembly+++GO:0050770///regulation of axonogenesis+++GO:0050790///regulation of catalytic activity+++GO:0097485///neuron projection guidance" 232910 232910 'Ap2s1' mRNA 1369 1375 1335 116.96 116.44 121.04 253.49 255.04 271.06 118.1466667 259.8633333 3396 3327 3506 1359.666667 3409.666667 5.11E-87 1.314662053 04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030122///AP-2 adaptor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0072583///clathrin-dependent endocytosis 232933 232933 'Ccdc61' mRNA 379 396 354 10.8 11.24 10.75 8.18 7.42 8.6 10.93 8.066666667 330 290 331 376.3333333 317 0.08016054 -0.25863417 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0120103///centriolar subdistal appendage GO:0008017///microtubule binding+++GO:0042802///identical protein binding GO:0030030///cell projection organization+++GO:0090307///mitotic spindle assembly+++GO:0098534///centriole assembly 232934 232934 'Mypop' mRNA 116 102 40 3.01 2.61 1.1 1.53 2.01 1.68 2.24 1.74 68 87 72 86 75.66666667 0.707798435 -0.176878203 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 232943 232943 'Klc3' mRNA 2153.72 2207.15 2029.66 66.92 67.35 66.72 34.12 34.23 37.3 66.99666667 35.21666667 1261.14 1240.22 1341.5 2130.176667 1280.953333 1.46E-24 -0.744434727 05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0031514///motile cilium+++GO:0035253///ciliary rootlet+++GO:0043005///neuron projection GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019894///kinesin binding GO:0008088///axo-dendritic transport+++GO:0042073///intraciliary transport 232944 232944 'Mark4' mRNA 224 249 187 3.4 3.67 3.01 3.16 3.69 3.26 3.36 3.37 242 274 241 220 252.3333333 0.33609818 0.1914819 GO:0000930///gamma-tubulin complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030425///dendrite+++GO:0030496///midbody+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043015///gamma-tubulin binding+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0016310///phosphorylation+++GO:0030030///cell projection organization+++GO:0035556///intracellular signal transduction+++GO:0044782///cilium organization+++GO:0045724///positive regulation of cilium assembly+++GO:0046605///regulation of centrosome cycle+++GO:0051301///cell division+++GO:1904781///positive regulation of protein localization to centrosome 232946 232946 'Bloc1s3' mRNA 186.9 183.69 77.88 5.7 5.54 2.5 2.82 5.52 5.67 4.58 4.67 105.73 202.89 207.01 149.49 171.8766667 0.583675133 0.215837728 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0031083///BLOC-1 complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity GO:0001654///eye development+++GO:0007596///blood coagulation+++GO:0008089///anterograde axonal transport+++GO:0009410///response to xenobiotic stimulus+++GO:0030168///platelet activation+++GO:0031175///neuron projection development+++GO:0032402///melanosome transport+++GO:0032438///melanosome organization+++GO:0032816///positive regulation of natural killer cell activation+++GO:0033299///secretion of lysosomal enzymes+++GO:0035646///endosome to melanosome transport+++GO:0042493///response to drug+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0048490///anterograde synaptic vesicle transport+++GO:0060155///platelet dense granule organization+++GO:0071806///protein transmembrane transport 232947 232947 'Ppp1r37' mRNA 396 379 256 7.33 6.9 5.02 4.95 5.27 4.5 6.416666667 4.906666667 308 320 271 343.6666667 299.6666667 0.298664716 -0.201382976 GO:0005575///cellular_component GO:0004864///protein phosphatase inhibitor activity GO:0010923///negative regulation of phosphatase activity+++GO:0043086///negative regulation of catalytic activity 232966 232966 'Zfp114' mRNA 87.8 52.82 64 1.56 0.96 1.25 0.23 0.68 0.6 1.256666667 0.503333333 14.22 42.13 36.19 68.20666667 30.84666667 0.01018215 -1.14648891 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0046328///regulation of JNK cascade+++GO:0051402///neuron apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1900112///regulation of histone H3-K9 trimethylation+++GO:1990009///retinal cell apoptotic process" 232969 232969 'Zfp428' mRNA 428 381 315 13.79 10.72 11.27 10.71 10.67 11.24 11.92666667 10.87333333 311 326 332 374.6666667 323 0.173512288 -0.221073456 GO:0046872///metal ion binding GO:0008150///biological_process 232970 232970 'Phldb3' mRNA 13 9 14 0.26 0.2 0.37 0.24 0.26 0.4 0.276666667 0.3 11 13 19 12 14.33333333 0.797480756 0.240434402 GO:0005575///cellular_component GO:0019899///enzyme binding GO:0008150///biological_process 232974 232974 'Erfl' mRNA 1 1 0 0.03 0.03 0 0.03 0 0.07 0.02 0.033333333 1 0 3 0.666666667 1.333333333 0.769474424 1.012963863 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0030154///cell differentiation" 232975 232975 'Atp1a3' mRNA 40 21 26 0.6 0.31 0.41 9.56 9.04 8.78 0.44 9.126666667 730 674 649 29 684.3333333 2.95E-110 4.549103976 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031090///organelle membrane+++GO:0042383///sarcolemma+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0044305///calyx of Held+++GO:0044326///dendritic spine neck+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:0098984///neuron to neuron synapse+++GO:0099056///integral component of presynaptic membrane GO:0000166///nucleotide binding+++GO:0001540///amyloid-beta binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0031748///D1 dopamine receptor binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0086037///sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential+++GO:0099520///ion antiporter activity involved in regulation of presynaptic membrane potential GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0007613///memory+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0009410///response to xenobiotic stimulus+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0021987///cerebral cortex development+++GO:0030007///cellular potassium ion homeostasis+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0036376///sodium ion export across plasma membrane+++GO:0042493///response to drug+++GO:0060048///cardiac muscle contraction+++GO:0071300///cellular response to retinoic acid+++GO:0071805///potassium ion transmembrane transport+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:1902600///proton transmembrane transport+++GO:1904646///cellular response to amyloid-beta+++GO:1990535///neuron projection maintenance+++GO:1990573///potassium ion import across plasma membrane 232976 232976 'Zfp574' mRNA 1210 1150 1020 19.04 17.33 17.15 15.1 14.19 14.28 17.84 14.52333333 1080 1017 1018 1126.666667 1038.333333 0.18899841 -0.127688805 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 232983 232983 'Cxcl17' mRNA 6 7 3 0.55 0.63 0.29 0.72 1.31 0.91 0.49 0.98 9 16 11 5.333333333 12 0.217886658 1.174289958 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0008009///chemokine activity GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0006935///chemotaxis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0030154///cell differentiation+++GO:0048246///macrophage chemotaxis+++GO:0050728///negative regulation of inflammatory response+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090026///positive regulation of monocyte chemotaxis 232984 232984 'B3gnt8' mRNA 24 25 20 0.84 0.87 0.65 8.22 7.43 7.43 0.786666667 7.693333333 264 233 245 23 247.3333333 4.69E-40 3.416279453 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016262///protein N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 232987 232987 'B9d2' mRNA 572 554 508 36.62 35.06 34.5 24.18 26.58 27.02 35.39333333 25.92666667 433 464 468 544.6666667 455 0.031179339 -0.26911302 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0036038///MKS complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding GO:0030030///cell projection organization+++GO:0060271///cilium assembly 232989 232989 'Hnrnpul1' mRNA 1554 1330 693 23.14 19.96 11.22 12.72 12.11 13.56 18.10666667 12.79666667 940 883 986 1192.333333 936.3333333 0.364600645 -0.34538146 05164///Influenza A GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003723///RNA binding+++GO:0019899///enzyme binding GO:0006396///RNA processing+++GO:0009615///response to virus 233011 233011 'Itpkc' mRNA 104.53 135.5 95.33 1.76 2.25 1.71 2.13 1.89 2.47 1.906666667 2.163333333 145 126.03 162.88 111.7866667 144.6366667 0.149422089 0.366863805 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000166///nucleotide binding+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity" GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0046854///phosphatidylinositol phosphorylation 233016 233016 'Blvrb' mRNA 687 677 649 52.8 51.53 52.93 91.87 90.98 93.11 52.42 91.98666667 1369 1318 1340 671 1342.333333 1.90E-31 0.988846338 00740///Riboflavin metabolism+++00860///Porphyrin metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle GO:0004074///biliverdin reductase activity+++GO:0016491///oxidoreductase activity+++GO:0042602///riboflavin reductase (NADPH) activity GO:0042167///heme catabolic process 233020 233020 'Hipk4' mRNA 17 8 13 0.42 0.2 0.33 0.27 0.46 0.23 0.316666667 0.32 11 18 9 12.66666667 12.66666667 0.997389888 -0.011533338 04218///Cellular senescence GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:1901796///regulation of signal transduction by p53 class mediator 233033 233033 'Samd4b' mRNA 735 679 605 8.99 8.17 7.85 8.31 8.25 8.06 8.336666667 8.206666667 782 758 734 673 758 0.155304991 0.161971884 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0030371///translation repressor activity GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0017148///negative regulation of translation+++GO:0043488///regulation of mRNA stability+++GO:0098749///cerebellar neuron development 233038 233038 'Nccrp1' mRNA 7 9 6 0.34 0.39 0.28 2.7 3.52 2.55 0.336666667 2.923333333 70 90 64 7.333333333 74.66666667 1.76E-12 3.341561253 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0061630///ubiquitin protein ligase activity GO:0006516///glycoprotein catabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 233040 233040 'Fbxo27' mRNA 366 433 391 10.09 11.73 11.63 5.79 7.28 6.51 11.15 6.526666667 249 290 265 396.6666667 268 1.30E-04 -0.575943189 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006516///glycoprotein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 233046 233046 'Rasgrp4' mRNA 172.78 158.57 139.85 2.01 1.82 1.72 1.96 1.56 1.8 1.85 1.773333333 193.68 150.87 167.32 157.0666667 170.6233333 0.675436133 0.109820959 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++05200///Pathways in cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding GO:0007264///small GTPase mediated signal transduction+++GO:0008283///cell proliferation+++GO:0009991///response to extracellular stimulus+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity 233056 233056 'Zfp790' mRNA 669.81 651.65 544.7 7.25 6.93 6.25 4.76 4.83 4.71 6.81 4.766666667 510.09 506.4 485.13 622.0533333 500.54 0.006396084 -0.320953507 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 233057 233057 'Zfp940' mRNA 215.06 200.32 222.07 3.31 3.09 3.65 2.75 2.4 2.79 3.35 2.646666667 208.95 177.75 203.77 212.4833333 196.8233333 0.563087299 -0.130495566 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 233058 233058 'Zfp420' mRNA 508.41 590.37 494.57 6.62 7.7 7.26 2.96 2.96 2.89 7.193333333 2.936666667 280 252.3 254.61 531.1166667 262.3033333 3.09E-15 -1.02870699 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0001835///blastocyst hatching+++GO:0006357///regulation of transcription by RNA polymerase II 233060 233060 'Zfp382' mRNA 188 165 199.99 1.24 1.08 1.41 1.41 1 1.24 1.243333333 1.216666667 245 171 208.47 184.33 208.1566667 0.51745047 0.158662345 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045892///negative regulation of transcription, DNA-templated" 233064 233064 'Wdr62' mRNA 28 30 30 0.3 0.31 0.33 1.87 1.65 1.88 0.313333333 1.8 197 170 189 29.33333333 185.3333333 6.17E-24 2.646551276 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0002052///positive regulation of neuroblast proliferation+++GO:0007052///mitotic spindle organization+++GO:0007099///centriole replication+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0045664///regulation of neuron differentiation+++GO:0046605///regulation of centrosome cycle+++GO:0097150///neuronal stem cell population maintenance+++GO:2001224///positive regulation of neuron migration 233065 233065 'Alkbh6' mRNA 959 967 1005 65.82 65.67 73.2 42.34 41.3 44.44 68.23 42.69333333 707 672 717 977 698.6666667 5.39E-07 -0.497435677 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion "GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0008150///biological_process 233066 233066 'Syne4' mRNA 2826 2684 2729 127.36 119.81 130.09 67.46 62.68 59.41 125.7533333 63.18333333 1725 1566 1452 2746.333333 1581 9.14E-26 -0.810284311 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031309///integral component of nuclear outer membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex GO:0005515///protein binding GO:0045198///establishment of epithelial cell apical/basal polarity 233067 233067 'Lrfn3' mRNA 105 123 99 2.02 2.33 2.02 1.37 1.95 1.56 2.123333333 1.626666667 82 114 90 109 95.33333333 0.527313859 -0.199732859 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0007155///cell adhesion+++GO:0099179///regulation of synaptic membrane adhesion+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 233071 233071 'Arhgap33' mRNA 732 696 539 9.01 8.42 6.98 3.3 3.45 3.21 8.136666667 3.32 308 314 290 655.6666667 304 6.27E-18 -1.115271872 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0035091///phosphatidylinositol binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0009636///response to toxic substance+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061001///regulation of dendritic spine morphogenesis 233073 233073 'U2af1l4' mRNA 826 791 772 63.58 60.3 63.06 42.75 46.92 48.5 62.31333333 46.05666667 636 680 697 796.3333333 671 0.017118929 -0.257874543 03040///Spliceosome+++05131///Shigellosis GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0089701///U2AF GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0048511///rhythmic process" 233079 233079 'Ffar2' mRNA 0 3 0 0 0.09 0 0.12 0.07 0 0.03 0.063333333 5 3 0 1 2.666666667 0.601224171 1.429183565 04024///cAMP signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0004930///G protein-coupled receptor activity+++GO:0008289///lipid binding GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002376///immune system process+++GO:0002385///mucosal immune response+++GO:0002673///regulation of acute inflammatory response+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002752///cell surface pattern recognition receptor signaling pathway+++GO:0002879///positive regulation of acute inflammatory response to non-antigenic stimulus+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019915///lipid storage+++GO:0032722///positive regulation of chemokine production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0042593///glucose homeostasis+++GO:0045444///fat cell differentiation+++GO:0071398///cellular response to fatty acid+++GO:0090276///regulation of peptide hormone secretion 233103 233103 'Garre1' mRNA 970 1094 1040 8.25 9.14 9.38 9.88 9.28 9.29 8.923333333 9.483333333 1340 1227 1219 1034.666667 1262 0.003306018 0.273504758 GO:0000932///P-body GO:0031267///small GTPase binding+++GO:1905762///CCR4-NOT complex binding GO:0016601///Rac protein signal transduction 233107 233107 'Kctd15' mRNA 184.78 210.48 170.11 4.12 4.8 4.06 1.92 2.41 1.87 4.326666667 2.066666667 95 118 90 188.4566667 101 3.38E-05 -0.903833481 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0051260///protein homooligomerization 233115 233115 'Dpy19l3' mRNA 391 430 404 2.68 2.91 2.94 2.26 1.9 2.19 2.843333333 2.116666667 377 310 356 408.3333333 347.6666667 0.098210254 -0.245175658 GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan 233147 233147 'Zfp939' mRNA 252.53 194.04 234.86 3.87 3.24 4.13 2.25 1.79 1.79 3.746666667 1.943333333 168.68 129.17 138.63 227.1433333 145.4933333 0.001254203 -0.660951077 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component 233164 233164 'Gm4884' mRNA 1 0 2 0.02 0 0.04 0 0 0.02 0.02 0.006666667 0 0 1 1 0.333333333 0.716186228 -1.529828329 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 233168 233168 'AI987944' mRNA 647.36 654.31 591.69 11.9 11.83 11.63 10.28 11.1 11.24 11.78666667 10.87333333 638.78 660.63 674.97 631.12 658.1266667 0.727961753 0.049860386 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 233186 233186 'Siglecf' mRNA 1 3 2 0.02 0.07 0.05 1.73 1.8 2.3 0.046666667 1.943333333 90 91 115 2 98.66666667 2.28E-16 5.614870431 GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0048029///monosaccharide binding GO:0007155///cell adhesion+++GO:0030100///regulation of endocytosis 233189 233189 'Ctu1' mRNA 182 179 195 4.13 4.01 4.69 4.37 3.76 3.95 4.276666667 4.026666667 221 186 194 185.3333333 200.3333333 0.691711048 0.096945826 04122///Sulfur relay system GO:0002144///cytosolic tRNA wobble base thiouridylase complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0002098///tRNA wobble uridine modification+++GO:0002143///tRNA wobble position uridine thiolation+++GO:0008033///tRNA processing+++GO:0032447///protein urmylation+++GO:0034227///tRNA thio-modification 233199 233199 'Mybpc2' mRNA 33 46.32 32 0.49 0.68 0.51 6.97 7.79 7.79 0.56 7.516666667 535.77 584.94 579.93 37.10666667 566.88 2.33E-90 3.927049279 GO:0005856///cytoskeleton+++GO:0032982///myosin filament GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton GO:0006936///muscle contraction+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion 233204 233204 'Tbc1d17' mRNA 2137 2078 2045 45.62 43.67 46.31 27.3 27.65 27.91 45.2 27.62 1471 1455 1456 2086.666667 1460.666667 2.33E-13 -0.52650199 04137///Mitophagy - animal GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity "GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0090630///activation of GTPase activity" 233208 233208 'Scaf1' mRNA 1530 1460 878 19.2 18.17 11.75 11.29 10.46 11.24 16.37333333 10.99666667 1036 938 989 1289.333333 987.6666667 0.00742089 -0.385916192 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0019904///protein domain specific binding+++GO:0099122///RNA polymerase II C-terminal domain binding GO:0006366///transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 233210 233210 'Prr12' mRNA 829 761 472 5.96 5.38 3.6 3.07 3.1 3.43 4.98 3.2 492 485 532 687.3333333 503 0.005189824 -0.451560737 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 233231 233231 'Mrgprb1' mRNA 2.31 1 1.63 0.03 0.01 0.02 0.02 0.01 0 0.02 0.01 1.87 1 0 1.646666667 0.956666667 0.751149362 -1.008936296 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0043303///mast cell degranulation+++GO:0045576///mast cell activation 233246 233246 'Ano5' mRNA 23 27 27 0.16 0.19 0.21 0.07 0.07 0.06 0.186666667 0.066666667 10 12 8 25.66666667 10 0.02635835 -1.37275272 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity+++GO:0046983///protein dimerization activity GO:0006821///chloride transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport 233271 233271 'Luzp2' mRNA 425 489 458 4.29 4.85 4.9 1.35 1.08 1.32 4.68 1.25 154 121 146 457.3333333 140.3333333 2.75E-28 -1.717933065 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 233274 233274 'Siglech' mRNA 56 56 74 1.88 1.41 2.59 0.59 1.05 0.78 1.96 0.806666667 24 31 24 62 26.33333333 0.001543388 -1.252661836 04640///Hematopoietic cell lineage GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0033691///sialic acid binding+++GO:0038024///cargo receptor activity GO:0006898///receptor-mediated endocytosis+++GO:0007155///cell adhesion 233276 233276 'Tubgcp5' mRNA 894 905 859 13.55 13.72 13.92 9.81 9.91 10.2 13.73 9.973333333 738 711 744 886 731 0.002897204 -0.288964879 GO:0000922///spindle pole+++GO:0000923///equatorial microtubule organizing center+++GO:0000930///gamma-tubulin complex+++GO:0000931///gamma-tubulin large complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0008274///gamma-tubulin ring complex GO:0008017///microtubule binding+++GO:0043015///gamma-tubulin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007020///microtubule nucleation+++GO:0031122///cytoplasmic microtubule organization+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle 233280 233280 'Nipa1' mRNA 75 66 64 2.24 1.95 2.03 1.38 1.47 1.43 2.073333333 1.426666667 53 55 53 68.33333333 53.66666667 0.314936201 -0.358975405 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015095///magnesium ion transmembrane transporter activity GO:0006811///ion transport+++GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 233315 233315 'Mtmr10' mRNA 1290 1351 1260 13.13 13.62 13.73 10.48 10.46 10.91 13.49333333 10.61666667 1170 1145 1176 1300.333333 1163.666667 0.046724412 -0.171521165 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0004438///phosphatidylinositol-3-phosphatase activity GO:0046856///phosphatidylinositol dephosphorylation 233328 233328 'Lrrk1' mRNA 1089 1050 954 7.72 7.33 7.18 5.53 5.06 5.61 7.41 5.4 899 805 882 1031 862 0.004232692 -0.269064915 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0036035///osteoclast development+++GO:0045453///bone resorption+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902533///positive regulation of intracellular signal transduction 233332 233332 'Adamts17' mRNA 108 111 95 0.96 0.98 0.89 0.46 0.53 0.58 0.943333333 0.523333333 59 66 70 104.6666667 65 0.012177142 -0.695621572 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization 233335 233335 'Synm' mRNA 1291 1311 1120 9.27 9.4 8.6 8.31 7.69 8.84 9.09 8.28 1327 1199 1371 1240.666667 1299 0.606974614 0.056610951 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0045111///intermediate filament cytoskeleton+++GO:0060053///neurofilament cytoskeleton "GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0017166///vinculin binding+++GO:0019215///intermediate filament binding+++GO:0030674///protein binding, bridging" GO:0031443///fast-twitch skeletal muscle fiber contraction+++GO:0045104///intermediate filament cytoskeleton organization 233405 233405 'Vps33b' mRNA 638.5 614.95 598.64 13.82 13.1 13.74 10.72 10.5 9.48 13.55333333 10.23333333 570 545.1 488.03 617.3633333 534.3766667 0.073173655 -0.218824724 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005773///vacuole+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031091///platelet alpha granule+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0033263///CORVET complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0006886///intracellular protein transport+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0030199///collagen fibril organization+++GO:0032400///melanosome localization+++GO:0032418///lysosome localization+++GO:0032963///collagen metabolic process+++GO:0035855///megakaryocyte development+++GO:0061025///membrane fusion+++GO:0070889///platelet alpha granule organization+++GO:0090330///regulation of platelet aggregation 233406 233406 'Prc1' mRNA 34 15 31 0.7 0.3 0.64 9.41 7.67 7.49 0.546666667 8.19 586 468 456 26.66666667 503.3333333 2.18E-73 4.221688039 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0070938///contractile ring+++GO:1990023///mitotic spindle midzone GO:0008017///microtubule binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0000910///cytokinesis+++GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0032465///regulation of cytokinesis+++GO:0051256///mitotic spindle midzone assembly+++GO:0051301///cell division 233410 233410 'Zfp592' mRNA 873 957 855 6.31 6.8 6.56 6.44 6.13 6.1 6.556666667 6.223333333 1026 954 941 895 973.6666667 0.294590179 0.110255216 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process 233424 233424 'Tmc3' mRNA 99 94 75 0.77 0.77 0.61 1.1 1.36 1.24 0.716666667 1.233333333 159 163 169 89.33333333 163.6666667 1.15E-04 0.866058876 GO:0005575///cellular_component+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 233489 233489 'Picalm' mRNA 617 606 718 8.34 8.36 10.12 18.79 16.37 17.31 8.94 17.49 1564 1320 1403 647 1429 1.38E-25 1.125508709 GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030132///clathrin coat of coated pit+++GO:0030136///clathrin-coated vesicle+++GO:0031224///intrinsic component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0070381///endosome to plasma membrane transport vesicle+++GO:0097418///neurofibrillary tangle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098794///postsynapse+++GO:0098894///extrinsic component of presynaptic endocytic zone membrane "GO:0000149///SNARE binding+++GO:0005543///phospholipid binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0017124///SH3 domain binding+++GO:0030276///clathrin binding+++GO:0031267///small GTPase binding+++GO:0032050///clathrin heavy chain binding+++GO:0042802///identical protein binding+++GO:0048156///tau protein binding+++GO:0050750///low-density lipoprotein particle receptor binding" "GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006900///vesicle budding from membrane+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0007611///learning or memory+++GO:0010629///negative regulation of gene expression+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0016188///synaptic vesicle maturation+++GO:0016192///vesicle-mediated transport+++GO:0016197///endosomal transport+++GO:0030097///hemopoiesis+++GO:0030100///regulation of endocytosis+++GO:0031623///receptor internalization+++GO:0032880///regulation of protein localization+++GO:0035459///cargo loading into vesicle+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0048268///clathrin coat assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0048813///dendrite morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0051223///regulation of protein transport+++GO:0055072///iron ion homeostasis+++GO:0072583///clathrin-dependent endocytosis+++GO:0090647///modulation of age-related behavioral decline+++GO:0097494///regulation of vesicle size+++GO:0097753///membrane bending+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1901216///positive regulation of neuron death+++GO:1902003///regulation of amyloid-beta formation+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1902803///regulation of synaptic vesicle transport+++GO:1902959///regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1902963///negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:1903861///positive regulation of dendrite extension+++GO:1905224///clathrin-coated pit assembly+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2000331///regulation of terminal button organization+++GO:2000809///positive regulation of synaptic vesicle clustering" 233490 233490 'Crebzf' mRNA 399 388 314 4.19 4.11 3.65 3.3 3.34 3.46 3.983333333 3.366666667 355 344 351 367 350 0.673649522 -0.076430757 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009615///response to virus+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051090///regulation of DNA-binding transcription factor activity" 233529 233529 'Kctd14' mRNA 426.01 430.03 450 10.52 10.48 11.76 10.02 8.73 9.28 10.92 9.343333333 465 399 419.43 435.3466667 427.81 0.828376865 -0.040279937 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0051260///protein homooligomerization 233532 233532 'Rsf1' mRNA 1158 1193 1045 5.44 5.5 5.2 4.07 3.4 4.27 5.38 3.913333333 998 816 1015 1132 943 0.007303929 -0.274585507 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031213///RSF complex GO:0003712///transcription coregulator activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006352///DNA-templated transcription, initiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016584///nucleosome positioning+++GO:0043392///negative regulation of DNA binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050434///positive regulation of viral transcription" 233537 233537 'Gdpd4' mRNA 5 1 1 0.09 0.02 0.02 0.03 0.02 0 0.043333333 0.016666667 2 1 0 2.333333333 1 0.627045727 -1.22993869 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0008150///biological_process 233545 233545 'Emsy' mRNA 1012.25 1167.74 1165.58 7.28 8.08 8.71 6.48 6.55 6.21 8.023333333 6.413333333 1033.44 985.97 947.86 1115.19 989.09 0.082609698 -0.187687224 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus" 233549 233549 'Mogat2' mRNA 1 2 1 0.03 0.06 0.03 0.03 0.17 0.12 0.04 0.106666667 1 6 4 1.333333333 3.666666667 0.438484477 1.466721135 00561///Glycerolipid metabolism+++04975///Fat digestion and absorption GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:1990578///perinuclear endoplasmic reticulum membrane "GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006071///glycerol metabolic process+++GO:0006629///lipid metabolic process+++GO:0006640///monoacylglycerol biosynthetic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0046462///monoacylglycerol metabolic process+++GO:0050892///intestinal absorption 233552 233552 'Gdpd5' mRNA 3714 3981 3853 43.61 46 48.04 22.47 21.56 21.83 45.88333333 21.95333333 2204 2083 2077 3849.333333 2121.333333 2.70E-40 -0.872556052 GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008889///glycerophosphodiester phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0047389///glycerophosphocholine phosphodiesterase activity GO:0006629///lipid metabolic process+++GO:0007399///nervous system development+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0031175///neuron projection development+++GO:0045666///positive regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045787///positive regulation of cell cycle+++GO:0048505///regulation of timing of cell differentiation 233571 233571 'P2ry6' mRNA 189 235 152 5.62 6.91 4.81 65.59 63.12 62.2 5.78 63.63666667 2529 2376 2320 192 2408.333333 6.76E-262 3.641208681 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0001621///ADP receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0019103///pyrimidine nucleotide binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045029///UDP-activated nucleotide receptor activity+++GO:0045030///UTP-activated nucleotide receptor activity "GO:0006909///phagocytosis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030321///transepithelial chloride transport+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071415///cellular response to purine-containing compound+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1905835///cellular response to pyrimidine ribonucleotide" 233575 233575 'Pgap2' mRNA 529.04 615.12 621.05 13.84 15.53 17.06 22.39 22.63 21.32 15.47666667 22.11333333 969 937 894 588.4033333 933.3333333 2.54E-09 0.65166668 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006506///GPI anchor biosynthetic process+++GO:0072659///protein localization to plasma membrane 233649 233649 'Cnga4' mRNA 9 3 4 0.13 0.07 0.06 0.03 0.05 0.03 0.086666667 0.036666667 2 4 2 5.333333333 2.666666667 0.505490771 -1.003134094 04024///cAMP signaling pathway+++04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017071///intracellular cyclic nucleotide activated cation channel complex+++GO:0043204///perikaryon GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005221///intracellular cyclic nucleotide activated cation channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0030552///cAMP binding+++GO:0030553///cGMP binding+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0007608///sensory perception of smell+++GO:0034220///ion transmembrane transport+++GO:0050896///response to stimulus+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 233651 233651 'Dchs1' mRNA 502 429 460 2.46 2.07 2.4 2.28 2.07 2.38 2.31 2.243333333 536 477 540 463.6666667 517.6666667 0.317756176 0.145643488 04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0045177///apical part of cell GO:0005509///calcium ion binding+++GO:0045296///cadherin binding GO:0000902///cell morphogenesis+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0003007///heart morphogenesis+++GO:0003183///mitral valve morphogenesis+++GO:0003192///mitral valve formation+++GO:0003273///cell migration involved in endocardial cushion formation+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0009653///anatomical structure morphogenesis+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016477///cell migration+++GO:0021915///neural tube development+++GO:0022008///neurogenesis+++GO:0034332///adherens junction organization+++GO:0035329///hippo signaling+++GO:0036342///post-anal tail morphogenesis+++GO:0043931///ossification involved in bone maturation+++GO:0048565///digestive tract development+++GO:0072006///nephron development+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0072659///protein localization to plasma membrane+++GO:0090102///cochlea development+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 233724 233724 'Tmem41b' mRNA 1614 1829 1726 23.37 25.89 26.47 18 16.94 16.94 25.24333333 17.29333333 1425 1312 1300 1723 1345.666667 1.09E-05 -0.369559731 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044233///Mitochondria-associated ER Membrane GO:0003674///molecular_function GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0007399///nervous system development 233726 233726 'Ipo7' mRNA 1057 1033 852 11.99 11.52 10.25 11.94 9.53 9.52 11.25333333 10.33 1212 945 936 980.6666667 1031 0.669690071 0.061744353 03013///Nucleocytoplasmic transport+++04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042393///histone binding+++GO:0046332///SMAD binding GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0045087///innate immune response 233733 233733 'Galnt18' mRNA 261 229 208 5.73 4.95 4.84 2.46 2.48 2.29 5.173333333 2.41 129 127 116 232.6666667 124 1.35E-06 -0.917492973 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation 233744 233744 'Spon1' mRNA 621 535 566 5.34 4.52 5.16 4.05 4.2 3.65 5.006666667 3.966666667 543 549 474 574 522 0.291717114 -0.149518387 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0050693///LBD domain binding GO:0007155///cell adhesion+++GO:0010954///positive regulation of protein processing+++GO:0032092///positive regulation of protein binding+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902993///positive regulation of amyloid precursor protein catabolic process 233752 233752 'Insc' mRNA 1145 1249 1131 27.48 29.4 28.66 8.46 8.49 8.51 28.51333333 8.486666667 401 393 389 1175 394.3333333 1.29E-60 -1.586261558 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0045179///apical cortex "GO:0008093///cytoskeletal adaptor activity+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging" GO:0000132///establishment of mitotic spindle orientation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008356///asymmetric cell division+++GO:0009786///regulation of asymmetric cell division+++GO:0030154///cell differentiation+++GO:0031647///regulation of protein stability+++GO:0045176///apical protein localization+++GO:0060487///lung epithelial cell differentiation 233765 233765 'Plekha7' mRNA 1618 1699 1560 17.27 18.01 17.74 10.38 10.79 10.4 17.67333333 10.52333333 1099 1120 1048 1625.666667 1089 6.45E-14 -0.588856783 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0046930///pore complex GO:0005515///protein binding+++GO:0070097///delta-catenin binding GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0045218///zonula adherens maintenance+++GO:0046931///pore complex assembly+++GO:0090136///epithelial cell-cell adhesion 233781 233781 'Xylt1' mRNA 11 24 19 0.2 0.42 0.36 0.22 0.41 0.18 0.326666667 0.27 14 26 11 18 17 0.913263459 -0.089942739 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030158///protein xylosyltransferase activity+++GO:0046872///metal ion binding" GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0034605///cellular response to heat+++GO:0043931///ossification involved in bone maturation+++GO:0048681///negative regulation of axon regeneration+++GO:0048706///embryonic skeletal system development+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process 233789 233789 'Smg1' mRNA 1182 1116 1191 3.94 3.66 4.21 3.88 3.2 3.62 3.936666667 3.566666667 1340 1079 1212 1163 1210.333333 0.750387006 0.04219292 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0031932///TORC2 complex GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042162///telomeric DNA binding+++GO:0046872///metal ion binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016242///negative regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032204///regulation of telomere maintenance+++GO:0038202///TORC1 signaling+++GO:0046777///protein autophosphorylation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:2001020///regulation of response to DNA damage stimulus" 233802 233802 'Thumpd1' mRNA 1196 1272 1331 22.77 23.83 26.88 20.2 20.72 21.87 24.49333333 20.93 1221 1223 1280 1266.333333 1241.333333 0.739263611 -0.042685047 GO:0005575///cellular_component GO:0003723///RNA binding GO:0006400///tRNA modification 233805 233805 'Dcun1d3' mRNA 269 308 235 2.53 2.85 2.36 2.39 2.4 2.53 2.58 2.44 292 284 301 270.6666667 292.3333333 0.598799647 0.103235064 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032182///ubiquitin-like protein binding+++GO:0097602///cullin family protein binding GO:0010225///response to UV-C+++GO:0010332///response to gamma radiation+++GO:0010564///regulation of cell cycle process+++GO:0030308///negative regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045116///protein neddylation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:2000434///regulation of protein neddylation+++GO:2000435///negative regulation of protein neddylation+++GO:2000436///positive regulation of protein neddylation 233806 233806 'Tmem159' mRNA 1140 1078 1100 47.49 44.18 48.5 36.91 38.26 41.24 46.72333333 38.80333333 1011 1025 1104 1106 1046.666667 0.403398691 -0.091626735 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0140042///lipid droplet formation 233810 233810 'Abca16' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 02010///ABC transporters GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0055085///transmembrane transport 233812 233812 'Mosmo' mRNA 371 325 290 6.11 5.7 5.17 4.48 4.04 4.66 5.66 4.393333333 288 256 292 328.6666667 278.6666667 0.136135022 -0.247742233 04340///Hedgehog signaling pathway GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0003674///molecular_function GO:0030154///cell differentiation+++GO:0031647///regulation of protein stability+++GO:0045664///regulation of neuron differentiation+++GO:0045879///negative regulation of smoothened signaling pathway 233813 233813 'Vwa3a' mRNA 1145 1161 1030 14.21 14.16 13.47 0.57 0.62 0.58 13.94666667 0.59 52 56 52 1112 53.33333333 5.55E-186 -4.391847696 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 233824 233824 'Cog7' mRNA 1908 2035 2024 36.51 38.34 41.11 30.51 28.49 27.52 38.65333333 28.84 1836 1675 1606 1989 1705.666667 0.00501434 -0.235638696 GO:0000139///Golgi membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0017119///Golgi transport complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function "GO:0006486///protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0033365///protein localization to organelle+++GO:0034067///protein localization to Golgi apparatus+++GO:0050821///protein stabilization" 233826 233826 'Palb2' mRNA 36 41 44 0.7 0.6 0.94 1.01 0.97 0.97 0.746666667 0.983333333 73 73 72 40.33333333 72.66666667 0.014244653 0.835116642 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001833///inner cell mass cell proliferation+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007498///mesoderm development+++GO:0009887///animal organ morphogenesis+++GO:0035264///multicellular organism growth+++GO:0036342///post-anal tail morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0048568///embryonic organ development 233833 233833 'Tnrc6a' mRNA 1201 1290 1249 7.76 8.12 8.4 5.85 5.17 5.76 8.093333333 5.593333333 1037 911 1009 1246.666667 985.6666667 1.14E-04 -0.352152281 GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016442///RISC complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0060090///molecular adaptor activity "GO:0006417///regulation of translation+++GO:0009267///cellular response to starvation+++GO:0031047///gene silencing by RNA+++GO:0032507///maintenance of protein location in cell+++GO:0035195///gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" 233836 233836 'Slc5a11' mRNA 176 161 185 3.99 3.36 4.4 1.1 1.88 1.6 3.916666667 1.526666667 59 85 74 174 72.66666667 1.34E-07 -1.272049546 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005412///glucose:sodium symporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006915///apoptotic process+++GO:0008643///carbohydrate transport+++GO:0032409///regulation of transporter activity+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 233863 233863 'Gtf3c1' mRNA 2329 2387 2437 17.91 18.05 19.88 14.67 14 13.72 18.61333333 14.13 2196 2048 1990 2384.333333 2078 0.006854824 -0.212370056 GO:0000127///transcription factor TFIIIC complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0042791///5S class rRNA transcription by RNA polymerase III 233865 233865 'Katnip' mRNA 568 649 553 4.49 4.84 4.46 2.5 2.04 2.62 4.596666667 2.386666667 371 296 381 590 349.3333333 4.70E-09 -0.767368767 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0003674///molecular_function GO:0090660///cerebrospinal fluid circulation 233870 233870 'Tufm' mRNA 1461 1413 1412 50.23 47.86 51.44 54.31 51.92 52.04 49.84333333 52.75666667 1816 1690 1681 1428.666667 1729 8.54E-04 0.262500889 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0042645///mitochondrial nucleoid+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0045471///response to ethanol+++GO:0070125///mitochondrial translational elongation 233871 233871 'Atxn2l' mRNA 3087.56 3075.9 1548.95 40.65 39.62 21.26 20.88 27.62 26.24 33.84333333 24.91333333 1801.63 2280 2177 2570.803333 2086.21 0.439760404 -0.294925679 04711///Circadian rhythm - fly+++05014///Amyotrophic lateral sclerosis+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0003723///RNA binding GO:0010603///regulation of cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly 233875 233875 'Ino80e' mRNA 677 721.27 670 23.82 24.75 24.58 29.29 31 28.81 24.38333333 29.7 923 918 849 689.4233333 896.6666667 2.07E-04 0.367985571 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031011///Ino80 complex GO:0003674///molecular_function GO:0006338///chromatin remodeling+++GO:0008150///biological_process 233876 233876 'Hirip3' mRNA 208 221 209 5.21 5.47 5.5 3.04 3.25 3.49 5.393333333 3.26 144 147 160 212.6666667 150.3333333 0.007459282 -0.511683908 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 233877 233877 'Kctd13' mRNA 453 491 369 15.96 17.05 13.79 12.54 11.81 13.69 15.6 12.68 409 376 432 437.6666667 405.6666667 0.473907788 -0.116915199 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043149///stress fiber assembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045740///positive regulation of DNA replication+++GO:0050806///positive regulation of synaptic transmission+++GO:0051260///protein homooligomerization+++GO:0061351///neural precursor cell proliferation 233878 233878 'Sez6l2' mRNA 56 57 33 0.78 0.76 0.47 0.16 0.29 0.25 0.67 0.233333333 13.03 22.05 19 48.66666667 18.02666667 0.002230666 -1.433013647 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0008344///adult locomotory behavior+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0060074///synapse maturation+++GO:0090036///regulation of protein kinase C signaling 233879 233879 'Asphd1' mRNA 11 6 2 0.55 0.3 0.12 0.09 0.09 0.09 0.323333333 0.09 2 1 1 6.333333333 1.333333333 0.139727297 -2.243852362 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity GO:0008150///biological_process+++GO:0018193///peptidyl-amino acid modification 233887 233887 'Zfp553' mRNA 670 750 720.92 10.85 11.95 12.38 8.39 7.93 7.78 11.72666667 8.033333333 597 551 535 713.64 561 0.001459571 -0.359711799 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 233890 233890 'Zfp768' mRNA 444 428 353 11.12 10.55 9.38 8.8 8.12 9.13 10.35 8.683333333 404 364 406 408.3333333 391.3333333 0.691714189 -0.070100174 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II" 233893 233893 'Zfp764' mRNA 208.18 260.97 232.02 4.63 5.71 5.48 4.58 3.15 4.29 5.273333333 4.006666667 237.24 159.25 215 233.7233333 203.83 0.347928221 -0.210644299 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 233895 233895 'Prr14' mRNA 2935.59 2985.56 2984.97 33.85 37.88 36.22 30.57 32.11 29.67 35.98333333 30.78333333 2791.28 2838.63 2784.68 2968.706667 2804.863333 0.222408461 -0.094328552 GO:0005634///nucleus+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003674///molecular_function GO:0007517///muscle organ development+++GO:0008150///biological_process 233899 233899 'Ccdc189' mRNA 1104.14 1103.76 973.66 37.83 37.16 37.64 10.72 10.45 10.23 37.54333333 10.46666667 375.18 391.07 358.34 1060.52 374.8633333 9.27E-51 -1.509841149 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 233900 233900 'Rnf40' mRNA 1495 1588 1515 19.45 20.27 20.87 17.08 15.14 16.97 20.19666667 16.39666667 1515 1311 1460 1532.666667 1428.666667 0.218762657 -0.114358093 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0032991///protein-containing complex+++GO:0033503///HULC complex+++GO:0043005///neuron projection+++GO:0043679///axon terminus GO:0003730///mRNA 3'-UTR binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010390///histone monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0033523///histone H2B ubiquitination+++GO:0043434///response to peptide hormone+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1902916///positive regulation of protein polyubiquitination+++GO:2001168///positive regulation of histone H2B ubiquitination 233902 233902 'Fbxl19' mRNA 67 86 57 0.97 1.18 0.87 0.83 0.71 0.86 1.006666667 0.8 74 60 69 70 67.66666667 0.884948855 -0.056192314 GO:0019005///SCF ubiquitin ligase complex GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0032452///histone demethylase activity+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0016577///histone demethylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 233904 233904 'Setd1a' mRNA 597 548 377 5.34 4.82 3.58 3.99 3.67 4.16 4.58 3.94 513 461 519 507.3333333 497.6666667 0.863328977 -0.032218056 00310///Lysine degradation GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0035097///histone methyltransferase complex+++GO:0048188///Set1C/COMPASS complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific) "GO:0006325///chromatin organization+++GO:0007420///brain development+++GO:0010628///positive regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0032259///methylation+++GO:0044648///histone H3-K4 dimethylation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0051568///histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0097692///histone H3-K4 monomethylation+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:1902275///regulation of chromatin organization+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000648///positive regulation of stem cell proliferation" 233905 233905 'Zfp646' mRNA 407.99 400.3 428.69 3.43 3.29 3.81 2.99 2.78 2.92 3.51 2.896666667 410.54 373.54 389.29 412.3266667 391.1233333 0.593128933 -0.089901556 GO:0005634///nucleus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0046872///metal ion binding GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 233908 233908 'Fus' mRNA 3892 4049 2034 119.58 122.93 65.82 65.16 67.66 71.83 102.7766667 68.21666667 2450 2474 2595 3325 2506.333333 0.208113237 -0.404131199 03015///mRNA surveillance pathway+++03040///Spliceosome+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0044327///dendritic spine head+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding+++GO:0031489///myosin V binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008380///RNA splicing+++GO:0010467///gene expression+++GO:0043484///regulation of RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048255///mRNA stabilization+++GO:0051260///protein homooligomerization+++GO:0071277///cellular response to calcium ion+++GO:1905168///positive regulation of double-strand break repair via homologous recombination" 233912 233912 'Armc5' mRNA 922.23 926.27 870.01 13.08 12.94 13.06 12.6 12.7 12.41 13.02666667 12.57 1025.62 1005.61 975.16 906.17 1002.13 0.174445303 0.133590238 04934///Cushing syndrome GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0016020///membrane GO:0003674///molecular_function "GO:0001701///in utero embryonic development+++GO:0001707///mesoderm formation+++GO:0007369///gastrulation+++GO:0035801///adrenal cortex development+++GO:0042098///T cell proliferation+++GO:0043367///CD4-positive, alpha-beta T cell differentiation+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051607///defense response to virus" 233913 233913 'Rusf1' mRNA 1052.17 1122.61 1053.42 23.24 24.8 25.46 15.06 18.65 19.03 24.5 17.58 752.85 948 963 1076.066667 887.95 0.016041911 -0.286415402 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 233919 233919 'Gpr26' mRNA 1 1 4 0.02 0.02 0.08 0 0 0 0.04 0 0 0 0 2 0 0.243478455 -3.490445993 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 233977 233977 'Ppfia1' mRNA 522 561 595 5.71 6.01 6.95 5.65 5.74 5.95 6.223333333 5.78 606 578 599 559.3333333 594.3333333 0.633537466 0.072991137 GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0048786///presynaptic active zone GO:0005515///protein binding GO:0050808///synapse organization+++GO:0051497///negative regulation of stress fiber assembly+++GO:1903077///negative regulation of protein localization to plasma membrane 233979 233979 'Tpcn2' mRNA 150 150 133 2.8 2.72 2.44 7.32 5.83 7.52 2.653333333 6.89 460 365 467 144.3333333 430.6666667 9.03E-23 1.565670291 04020///Calcium signaling pathway+++04972///Pancreatic secretion GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036020///endolysosome membrane "GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0072345///NAADP-sensitive calcium-release channel activity+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0097682///intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006939///smooth muscle contraction+++GO:0007040///lysosome organization+++GO:0010506///regulation of autophagy+++GO:0017157///regulation of exocytosis+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0019722///calcium-mediated signaling+++GO:0033280///response to vitamin D+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0075509///endocytosis involved in viral entry into host cell+++GO:0090117///endosome to lysosome transport of low-density lipoprotein particle+++GO:0098655///cation transmembrane transport 233987 233987 'Zfp958' mRNA 352 351 359 4.01 3.93 4.34 3.97 3.49 3.07 4.093333333 3.51 401 345 300 354 348.6666667 0.863090843 -0.036425421 05168///Herpes simplex virus 1 infection GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 234023 234023 'Arglu1' mRNA 4055 3358 4303 133.55 108.26 148.98 83.2 84.61 85.82 130.2633333 84.54333333 2918 2873 2917 3905.333333 2902.666667 5.76E-06 -0.445425449 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane 234069 234069 'Pcid2' mRNA 960.75 887.85 1012.52 15.86 14.18 16.97 14.96 13.3 14.68 15.67 14.31333333 979.88 897.91 972.96 953.7066667 950.25 0.875409689 -0.021022447 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0044615///nuclear pore nuclear basket+++GO:0070390///transcription export complex 2 GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding "GO:0000973///posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0043488///regulation of mRNA stability+++GO:0045579///positive regulation of B cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048536///spleen development+++GO:0071033///nuclear retention of pre-mRNA at the site of transcription+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:2000117///negative regulation of cysteine-type endopeptidase activity" 234072 234072 'Adprhl1' mRNA 162 157 169 6.91 6.63 7.64 1.12 1.44 1.44 7.06 1.333333333 30 38 39 162.6666667 35.66666667 1.29E-16 -2.20180429 GO:0000287///magnesium ion binding+++GO:0003875///ADP-ribosylarginine hydrolase activity+++GO:0005096///GTPase activator activity+++GO:0016787///hydrolase activity GO:0006886///intracellular protein transport+++GO:0051725///protein de-ADP-ribosylation+++GO:0090630///activation of GTPase activity 234076 234076 'Tmco3' mRNA 2335.3 2438.49 2286.1 27.26 28.25 28.47 15.1 14.72 15.23 27.99333333 15.01666667 1502.06 1406.64 1464.64 2353.296667 1457.78 1.29E-24 -0.703011587 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0008150///biological_process+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 234086 234086 'Erich1' mRNA 217.77 227.98 237.42 7.41 7.85 9.03 6.96 8.25 7.36 8.096666667 7.523333333 235.98 259.92 239.29 227.7233333 245.0633333 0.673276919 0.093398353 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234094 234094 'Arhgef10' mRNA 2371 2340 2132 16.75 15.66 15.25 8.8 8.96 8.66 15.88666667 8.806666667 1396 1415 1342 2281 1384.333333 2.36E-25 -0.73064695 GO:0005813///centrosome+++GO:0005829///cytosol GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019894///kinesin binding GO:0022011///myelination in peripheral nervous system+++GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051298///centrosome duplication+++GO:0051496///positive regulation of stress fiber assembly+++GO:0090307///mitotic spindle assembly+++GO:0090630///activation of GTPase activity 234135 234135 'Nsd3' mRNA 1467 1439 1326 19.26 18.47 18.02 18.07 19.37 18.51 18.58333333 18.65 1602 1665 1622 1410.666667 1629.666667 0.0138463 0.198133608 00310///Lysine degradation GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific)+++GO:0046976///histone methyltransferase activity (H3-K27 specific) "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010452///histone H3-K36 methylation+++GO:0016571///histone methylation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051568///histone H3-K4 methylation+++GO:0070734///histone H3-K27 methylation+++GO:2001255///positive regulation of histone H3-K36 trimethylation" 234138 234138 'Tti2' mRNA 352.37 378.73 391.08 6.94 7.61 8.52 6.36 7.16 6.04 7.69 6.52 354.22 382.21 328.64 374.06 355.0233333 0.632875832 -0.088494526 GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0070209///ASTRA complex GO:0003674///molecular_function GO:0008150///biological_process 234155 234155 'Mboat4' mRNA 1 1 1 0.03 0.03 0.03 0.03 0.18 0.18 0.03 0.13 1 6 6 1 4.333333333 0.246086267 2.114709441 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0016412///serine O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0018191///peptidyl-serine octanoylation+++GO:0030258///lipid modification 234199 234199 'Fgl1' mRNA 2 2 5 0.11 0.11 0.3 0.93 1.74 1.32 0.173333333 1.33 19 35 27 3 27 6.61E-05 3.153125034 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0008203///cholesterol metabolic process+++GO:0010906///regulation of glucose metabolic process+++GO:0035634///response to stilbenoid+++GO:0050776///regulation of immune response+++GO:0050868///negative regulation of T cell activation+++GO:0060612///adipose tissue development+++GO:0072574///hepatocyte proliferation 234214 234214 'Sorbs2' mRNA 10472 11091 10893 115.13 119.18 127.33 45.39 43.37 43.34 120.5466667 44.03333333 4699 4408 4396 10818.66667 4501 2.93E-108 -1.278597003 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding GO:0007015///actin filament organization+++GO:0007219///Notch signaling pathway+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1904393///regulation of skeletal muscle acetylcholine-gated channel clustering 234219 234219 'Helt' mRNA 1 3 2 0.04 0.11 0.08 1.97 2.19 2.54 0.076666667 2.233333333 55 61 68 2 61.33333333 1.15E-11 4.929625329 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001967///suckling behavior+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0009791///post-embryonic development+++GO:0009952///anterior/posterior pattern specification+++GO:0010259///multicellular organism aging+++GO:0010467///gene expression+++GO:0021858///GABAergic neuron differentiation in basal ganglia+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0035264///multicellular organism growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050767///regulation of neurogenesis" 234258 234258 'Neil3' mRNA 4 6 2 0.1 0.15 0.05 1.26 1.27 2.02 0.1 1.516666667 58 57 90 4 68.33333333 2.27E-12 4.090544871 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome "GO:0000405///bubble DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016829///lyase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0046872///metal ion binding+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:1904931///MCM complex binding" GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0036297///interstrand cross-link repair 234267 234267 'Gpm6a' mRNA 4199 4408 4276 77.76 80.39 84.07 58.77 56.58 61.56 80.74 58.97 3649 3434 3701 4294.333333 3594.666667 2.77E-05 -0.269233817 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044295///axonal growth cone+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0005262///calcium channel activity GO:0001764///neuron migration+++GO:0003407///neural retina development+++GO:0007399///nervous system development+++GO:0007416///synapse assembly+++GO:0009617///response to bacterium+++GO:0031175///neuron projection development+++GO:0048812///neuron projection morphogenesis+++GO:0048863///stem cell differentiation+++GO:0050807///regulation of synapse organization+++GO:0051491///positive regulation of filopodium assembly+++GO:0070588///calcium ion transmembrane transport 234290 234290 'BC030500' mRNA 3 0 0 0.11 0 0 0 0 0 0.036666667 0 0 0 0 1 0 0.653555534 -2.427804616 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234309 234309 'Cbr4' mRNA 218 248 219 12.19 13.7 12.99 16.18 13.4 15.63 12.96 15.07 332 268 310 228.3333333 303.3333333 0.017128959 0.397532208 00061///Fatty acid biosynthesis+++01212///Fatty acid metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:1990204///oxidoreductase complex "GO:0003955///NAD(P)H dehydrogenase (quinone) activity+++GO:0004316///3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity+++GO:0008753///NADPH dehydrogenase (quinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0047025///3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity+++GO:0048038///quinone binding+++GO:0070402///NADPH binding+++GO:0102131///3-oxo-glutaryl-[acp] methyl ester reductase activity+++GO:0102132///3-oxo-pimeloyl-[acp] methyl ester reductase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0051289///protein homotetramerization+++GO:0051290///protein heterotetramerization 234311 234311 'Ddx60' mRNA 551 587 481 6.2 6.41 5.77 7.23 7.83 7.47 6.126666667 7.51 759 794 730 539.6666667 761 6.83E-06 0.487455609 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0009615///response to virus+++GO:0051607///defense response to virus+++GO:1900245///positive regulation of MDA-5 signaling pathway+++GO:1900246///positive regulation of RIG-I signaling pathway 234344 234344 'Naf1' mRNA 96 96 44 1.85 1.77 0.86 0.65 0.54 0.96 1.493333333 0.716666667 41 33 58 78.66666667 44 0.03468463 -0.83578261 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0043489///RNA stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:0090669///telomerase RNA stabilization+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1905323///telomerase holoenzyme complex assembly 234353 234353 'Psd3' mRNA 638 608 532 4.02 3.87 3.76 3.51 3.37 3.33 3.883333333 3.403333333 571 540 569 592.6666667 560 0.500483686 -0.091328051 04144///Endocytosis+++04361///Axon regeneration GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005543///phospholipid binding GO:0032011///ARF protein signal transduction+++GO:0032012///regulation of ARF protein signal transduction 234356 234356 'Csgalnact1' mRNA 227 251 255 3.06 3.3 3.62 1.57 1.37 1.18 3.326666667 1.373333333 135 116 102 244.3333333 117.6666667 3.99E-08 -1.069220341 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008955///peptidoglycan glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0047237///glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity "GO:0001958///endochondral ossification+++GO:0019276///UDP-N-acetylgalactosamine metabolic process+++GO:0030198///extracellular matrix organization+++GO:0030204///chondroitin sulfate metabolic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0046398///UDP-glucuronate metabolic process+++GO:0050653///chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0051216///cartilage development" 234358 234358 'Zfp930' mRNA 586.21 584.36 524.36 10.59 10.36 10.08 5.43 5.21 5.5 10.34333333 5.38 344 327 341.1 564.9766667 337.3666667 2.20E-10 -0.753564928 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 234362 234362 'Zfp868' mRNA 1115.57 1052.46 1245.99 25.2 23.49 30.21 15.91 16.34 16.75 26.3 16.33333333 805.73 813.24 829.7 1138.006667 816.2233333 5.58E-06 -0.495549273 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 234365 234365 'Yjefn3' mRNA 79 65 69 6.81 5.55 6.31 6.47 6.18 6.55 6.223333333 6.4 86 80 84 71 83.33333333 0.523388691 0.218708741 GO:0005739///mitochondrion GO:0052856///NADHX epimerase activity+++GO:0052857///NADPHX epimerase activity GO:0002040///sprouting angiogenesis+++GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0008593///regulation of Notch signaling pathway+++GO:0010874///regulation of cholesterol efflux+++GO:0016525///negative regulation of angiogenesis+++GO:0031580///membrane raft distribution+++GO:0071425///hematopoietic stem cell proliferation 234366 234366 'Gatad2a' mRNA 894 904 833 12.43 12.46 12.06 16.85 16.05 16.25 12.31666667 16.38333333 1325 1253 1263 877 1280.333333 9.28E-11 0.534740154 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016581///NuRD complex+++GO:0016607///nuclear speck "GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001842///neural fold formation+++GO:0010172///embryonic body morphogenesis+++GO:0012501///programmed cell death+++GO:0021506///anterior neuropore closure+++GO:0045892///negative regulation of transcription, DNA-templated" 234371 234371 'Tmem161a' mRNA 1989 2065 1971 50.67 51.15 52.83 40.51 42.62 40.91 51.55 41.34666667 1847 1871 1791 2008.333333 1836.333333 0.070833932 -0.140785792 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032526///response to retinoic acid+++GO:0034599///cellular response to oxidative stress+++GO:0034644///cellular response to UV+++GO:0045739///positive regulation of DNA repair+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 234373 234373 'Sugp2' mRNA 799.07 845.05 736.7 9.81 9.84 9.24 6.34 7.06 5.94 9.63 6.446666667 617.86 692.73 565.42 793.6066667 625.3366667 0.002013096 -0.353878954 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 234374 234374 'Ddx49' mRNA 700.21 707.92 712.35 18.89 18.81 20.38 20.39 19.76 18.9 19.36 19.68333333 869.17 822.42 779.88 706.8266667 823.8233333 0.053925786 0.207978235 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0030307///positive regulation of cell growth+++GO:0044357///regulation of rRNA stability 234378 234378 'Klhl26' mRNA 875 835 871 15.15 14.23 16.03 11.18 11.83 12.11 15.13666667 11.70666667 730 763 775 860.3333333 756 0.068018219 -0.19899159 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234384 234384 'Mpv17l2' mRNA 1184 1067 1166 78.86 69.82 82.34 93.19 100.26 94.21 77.00666667 95.88666667 1609 1686 1569 1139 1621.333333 3.85E-08 0.496239834 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0061668///mitochondrial ribosome assembly+++GO:0070131///positive regulation of mitochondrial translation 234388 234388 'Ccdc124' mRNA 1103 1097 1038 78.97 78.01 79.13 98.79 102.87 97.84 78.70333333 99.83333333 1577 1597 1508 1079.333333 1560.666667 4.51E-11 0.520982429 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030496///midbody GO:0003713///transcription coactivator activity GO:0006366///transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0008150///biological_process+++GO:0051301///cell division 234395 234395 'Ushbp1' mRNA 181 178 143 3.75 3.74 3.02 5.14 5.04 6.48 3.503333333 5.553333333 272 270 338 167.3333333 293.3333333 7.45E-06 0.802389164 GO:0005575///cellular_component GO:0030165///PDZ domain binding GO:0008150///biological_process 234396 234396 'Ankle1' mRNA 19.82 16.65 25.91 0.13 0.13 0.25 2.6 2.45 2.2 0.17 2.416666667 170.28 157.1 136.65 20.79333333 154.6766667 3.73E-21 2.930793282 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity GO:0006281///DNA repair+++GO:0006611///protein export from nucleus+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008340///determination of adult lifespan+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0043249///erythrocyte maturation+++GO:0045577///regulation of B cell differentiation+++GO:0045950///negative regulation of mitotic recombination+++GO:0046637///regulation of alpha-beta T cell differentiation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905453///regulation of myeloid progenitor cell differentiation+++GO:1905456///regulation of lymphoid progenitor cell differentiation+++GO:2001020///regulation of response to DNA damage stimulus+++GO:2001022///positive regulation of response to DNA damage stimulus 234404 234404 'Nxnl1' mRNA 34 56 61 0.68 1.1 1.29 0.81 0.71 0.64 1.023333333 0.72 47 40 36 50.33333333 41 0.506154635 -0.315442054 GO:0001750///photoreceptor outer segment+++GO:0005739///mitochondrion+++GO:0042995///cell projection GO:0005515///protein binding GO:0045494///photoreceptor cell maintenance 234407 234407 'Colgalt1' mRNA 1358 1367 1174 23.64 23.44 21.69 32.75 31.78 31.44 22.92333333 31.99 2165 2048 2015 1299.666667 2076 4.92E-20 0.665968623 00310///Lysine degradation+++00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0050211///procollagen galactosyltransferase activity" GO:1904028///positive regulation of collagen fibril organization 234413 234413 'Zfp961' mRNA 290 314 281 5.9 6.29 6.07 5.22 5.27 5.45 6.086666667 5.313333333 295 291 298 295 294.6666667 0.951947453 -0.012240654 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 234421 234421 'Cib3' mRNA 7275 7257 6986 696.75 682.46 709.78 44.89 48.71 46.67 696.33 46.75666667 547 572 533 7172.666667 550.6666667 0 -3.714825532 GO:0005575///cellular_component GO:0000287///magnesium ion binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 234463 234463 'Tmem184c' mRNA 1280 1330 1374 26.99 27.79 31.34 17.93 17.46 18.89 28.70666667 18.09333333 963 922 991 1328 958.6666667 1.18E-07 -0.483950417 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity GO:0006810///transport 234515 234515 'Inpp4b' mRNA 152 120 123 1.47 1.32 1.48 1.45 0.94 1.47 1.423333333 1.286666667 162 100 153.64 131.6666667 138.5466667 0.863090843 0.057026582 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008289///lipid binding+++GO:0016316///phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0017161///inositol-1,3,4-trisphosphate 4-phosphatase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0034594///phosphatidylinositol trisphosphate phosphatase activity+++GO:0034597///phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity+++GO:0052828///inositol-3,4-bisphosphate 4-phosphatase activity" GO:0006874///cellular calcium ion homeostasis+++GO:0016311///dephosphorylation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0046850///regulation of bone remodeling+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0051896///regulation of protein kinase B signaling 234542 234542 'Rtbdn' mRNA 70.92 54.03 67.25 0.92 0.65 1.14 0.15 0.16 0.22 0.903333333 0.176666667 15.16 14.64 20.32 64.06666667 16.70666667 2.11E-06 -1.977592989 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0033165///interphotoreceptor matrix GO:0032217///riboflavin transmembrane transporter activity+++GO:0038023///signaling receptor activity+++GO:1902444///riboflavin binding GO:0032218///riboflavin transport 234549 234549 'Heatr3' mRNA 692 651 720 12.04 11.15 13.29 11.6 12.71 10.9 12.16 11.73666667 767 821 698 687.6666667 762 0.314446685 0.134283511 GO:0051082///unfolded protein binding GO:0006606///protein import into nucleus+++GO:0042273///ribosomal large subunit biogenesis 234577 234577 'Cpne2' mRNA 67 58 37 1.63 1.39 0.96 4.13 5.67 5.74 1.326666667 5.18 195 261 262 54 239.3333333 2.07E-18 2.146472548 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045334///clathrin-coated endocytic vesicle GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0071277///cellular response to calcium ion 234582 234582 'Ccdc102a' mRNA 328 385 348 7.91 9.17 8.92 10.09 10.82 10.79 8.666666667 10.56666667 479 502 495 353.6666667 492 4.15E-04 0.465414378 GO:0005575///cellular_component+++GO:0016459///myosin complex GO:0003674///molecular_function GO:0008150///biological_process 234593 234593 'Ndrg4' mRNA 518 533 567 10.42 10.56 12.11 7.81 7.7 8.57 11.03 8.026666667 448 431 475 539.3333333 451.3333333 0.040540111 -0.271097866 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016323///basolateral plasma membrane+++GO:0031253///cell projection membrane GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007420///brain development+++GO:0008542///visual learning+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0048278///vesicle docking+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0060973///cell migration involved in heart development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2001135///regulation of endocytic recycling 234594 234594 'Cnot1' mRNA 1732.08 1637.61 1457.43 10.52 9.82 9.31 9.24 8.2 9.11 9.883333333 8.85 1742.51 1515.8 1674.63 1609.04 1644.313333 0.863090843 0.0206058 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0060090///molecular adaptor activity+++GO:0070016///armadillo repeat domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0001829///trophectodermal cell differentiation+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035195///gene silencing by miRNA+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:2000036///regulation of stem cell population maintenance" 234595 234595 'Slc38a7' mRNA 558 512 482 9.4 8.35 8.55 13.89 12.66 12.46 8.766666667 13.00333333 944 855 826 517.3333333 875 5.76E-13 0.74681834 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0005290///L-histidine transmembrane transporter activity+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015182///L-asparagine transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015190///L-leucine transmembrane transporter activity+++GO:0015191///L-methionine transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport+++GO:0006867///asparagine transport+++GO:0006868///glutamine transport+++GO:0015711///organic anion transport+++GO:0015803///branched-chain amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0015808///L-alanine transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0015821///methionine transport+++GO:0015825///L-serine transport+++GO:0070778///L-aspartate transmembrane transport+++GO:0089709///L-histidine transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport 234663 234663 'Dync1li2' mRNA 2309 2196 1990 27.23 25.35 25.12 23.17 21.54 22.91 25.9 22.54 2302 2083.92 2189 2165 2191.64 0.943804483 0.006819312 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0045504///dynein heavy chain binding GO:0000226///microtubule cytoskeleton organization+++GO:0007018///microtubule-based movement+++GO:0051642///centrosome localization+++GO:1990090///cellular response to nerve growth factor stimulus 234664 234664 'Nae1' mRNA 1062 1086 1068 33.92 34.22 36.25 26.71 25.18 28.44 34.79666667 26.77666667 958 879 984 1072 940.3333333 0.037829371 -0.2017877 05010///Alzheimer disease GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0019781///NEDD8 activating enzyme activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046982///protein heterodimerization activity GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0032446///protein modification by small protein conjugation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0042981///regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0045116///protein neddylation+++GO:0051402///neuron apoptotic process 234669 234669 'Ces2b' mRNA 406.36 419.51 382.28 6.53 6.62 6.52 1.79 1.77 1.51 6.556666667 1.69 128.17 123.86 104.85 402.7166667 118.96 1.61E-28 -1.776728984 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process 234671 234671 'Ces2c' mRNA 228.07 220.08 217.78 6.6 6.28 6.69 0.4 0.26 0.55 6.523333333 0.403333333 16 10.03 21.07 221.9766667 15.7 1.16E-37 -3.835472894 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0047619///acylcarnitine hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity" GO:0001101///response to acid chemical+++GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process+++GO:0042572///retinol metabolic process 234673 234673 'Ces2e' mRNA 10.28 10.59 16.49 0.29 0.3 0.5 0.35 0.73 0.64 0.363333333 0.573333333 14 29 26 12.45333333 23 0.178200214 0.923026499 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle "GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0047376///all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102209///trans-permethrin hydrolase activity" GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process+++GO:0042572///retinol metabolic process 234678 234678 'D230025D16Rik' mRNA 714.05 694.16 739.98 13.65 13.07 15.01 14.59 14.17 15.48 13.91 14.74666667 876.92 831.2 900.19 716.0633333 869.4366667 0.012847802 0.266302347 GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane GO:0030165///PDZ domain binding+++GO:0035254///glutamate receptor binding GO:0043001///Golgi to plasma membrane protein transport 234683 234683 'Elmo3' mRNA 1284 1402 1329 27.53 29 30.42 16.59 15.64 15.16 28.98333333 15.79666667 909 824 792 1338.333333 841.6666667 2.60E-14 -0.682042131 05100///Bacterial invasion of epithelial cells GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0007015///actin filament organization+++GO:0016477///cell migration+++GO:0048870///cell motility 234684 234684 'Lrrc29' mRNA 79 102 130 1.93 2.59 3.54 2.28 2.41 1.9 2.686666667 2.196666667 99 107 85 103.6666667 97 0.757973002 -0.115629082 GO:0019005///SCF ubiquitin ligase complex GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 234686 234686 'Fhod1' mRNA 88 95 71 1.24 1.39 1.06 2.47 1.96 2.03 1.23 2.153333333 190 151 154 84.66666667 165 3.55E-05 0.953107421 05132///Salmonella infection GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0014704///intercalated disc+++GO:0032059///bleb+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0051015///actin filament binding GO:0007097///nuclear migration+++GO:0030866///cortical actin cytoskeleton organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051492///regulation of stress fiber assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051639///actin filament network formation+++GO:0051660///establishment of centrosome localization 234695 234695 'Carmil2' mRNA 58 63 22 0.73 0.77 0.29 0.06 0.19 0.08 0.596666667 0.11 5 17 7 47.66666667 9.666666667 1.23E-04 -2.287342622 GO:0001726///ruffle+++GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008290///F-actin capping protein complex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0044354///macropinosome+++GO:0045111///intermediate filament cytoskeleton GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0044877///protein-containing complex binding "GO:0007163///establishment or maintenance of cell polarity+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016477///cell migration+++GO:0030011///maintenance of cell polarity+++GO:0030335///positive regulation of cell migration+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0044319///wound healing, spreading of cells+++GO:0045184///establishment of protein localization+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0048538///thymus development+++GO:0048872///homeostasis of number of cells+++GO:0050852///T cell receptor signaling pathway+++GO:0051639///actin filament network formation+++GO:0061339///establishment or maintenance of monopolar cell polarity+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1900029///positive regulation of ruffle assembly+++GO:1902745///positive regulation of lamellipodium organization+++GO:2000813///negative regulation of barbed-end actin filament capping" 234699 234699 'Edc4' mRNA 1582 1550 1486 17.73 17.09 17.66 13.05 12.52 13.6 17.49333333 13.05666667 1341 1256 1354 1539.333333 1317 0.00316558 -0.236762804 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005515///protein binding GO:0031087///deadenylation-independent decapping of nuclear-transcribed mRNA 234700 234700 'Nrn1l' mRNA 14 9 11 1.72 1.1 1.44 1.5 1.77 1.34 1.42 1.536666667 14 16 12 11.33333333 14 0.749855753 0.293144538 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007399///nervous system development+++GO:1990138///neuron projection extension 234723 234723 'Txnl4b' mRNA 465 512 468 14.1 15.3 15.05 10.92 11.73 10.57 14.81666667 11.07333333 414 434 388 481.6666667 412 0.080376791 -0.236286842 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005829///cytosol+++GO:0046540///U4/U6 x U5 tri-snRNP complex GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing" 234724 234724 'Tat' mRNA 4 3 2 0.09 0.07 0.05 0 0.02 0.02 0.07 0.013333333 0 1 1 3 0.666666667 0.330491751 -2.163729127 "00130///Ubiquinone and other terpenoid-quinone biosynthesis+++00270///Cysteine and methionine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis" GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0004838///L-tyrosine:2-oxoglutarate aminotransferase activity+++GO:0008483///transaminase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding GO:0006103///2-oxoglutarate metabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006572///tyrosine catabolic process+++GO:0006979///response to oxidative stress+++GO:0009058///biosynthetic process+++GO:0009072///aromatic amino acid family metabolic process+++GO:0009074///aromatic amino acid family catabolic process+++GO:0014070///response to organic cyclic compound+++GO:0046689///response to mercury ion+++GO:0051384///response to glucocorticoid 234725 234725 'Zfp612' mRNA 1865 1957 1913 19.36 20.03 21.29 8.41 7.88 8.1 20.22666667 8.13 950 856 866 1911.666667 890.6666667 7.26E-44 -1.115158562 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 234728 234728 'Cmtr2' mRNA 197 197 189 2.99 2.91 3.01 2.24 1.94 1.87 2.97 2.016666667 170 144 138 194.3333333 150.6666667 0.062126271 -0.38010111 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004483///mRNA (nucleoside-2'-O-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0032259///methylation+++GO:0097309///cap1 mRNA methylation+++GO:0097310///cap2 mRNA methylation 234729 234729 'Vac14' mRNA 213 201 154 3.76 3.51 2.89 4.13 3.95 5.39 3.386666667 4.49 269 251 340 189.3333333 286.6666667 0.001807184 0.591987283 05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0000306///extrinsic component of vacuolar membrane+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070772///PAS complex GO:0019209///kinase activator activity+++GO:0042802///identical protein binding GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006970///response to osmotic stress+++GO:0033674///positive regulation of kinase activity 234730 234730 'Fcsk' mRNA 370 315 379 5.34 4.65 5.97 4.03 4.26 4.41 5.32 4.233333333 305 303 344 354.6666667 317.3333333 0.328305037 -0.175347787 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005575///cellular_component "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0050201///fucokinase activity" GO:0016310///phosphorylation+++GO:0042352///GDP-L-fucose salvage+++GO:0046835///carbohydrate phosphorylation+++GO:1903350///response to dopamine 234733 234733 'Ddx19b' mRNA 377.62 384.56 343.1 3.02 3.02 2.91 2.81 2.62 2.85 2.983333333 2.76 404.65 368.32 398.23 368.4266667 390.4 0.669398365 0.073033343 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0010494///cytoplasmic stress granule GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0016973///poly(A)+ mRNA export from nucleus 234734 234734 'Aars' mRNA 1860.06 1903.3 1934.95 26.87 26.96 29.53 29.55 31.24 29.64 27.78666667 30.14333333 2359.86 2429.66 2290.37 1899.436667 2359.963333 1.01E-04 0.300310881 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0002196///Ser-tRNA(Ala) hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016597///amino acid binding+++GO:0016874///ligase activity+++GO:0045182///translation regulator activity+++GO:0046872///metal ion binding GO:0006400///tRNA modification+++GO:0006412///translation+++GO:0006419///alanyl-tRNA aminoacylation+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0043039///tRNA aminoacylation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity+++GO:0140018///regulation of cytoplasmic translational fidelity 234736 234736 'Rfwd3' mRNA 1046 1076 1159 12.64 12.79 14.86 10.89 10.87 10.8 13.43 10.85333333 1037 1011 996 1093.666667 1014.666667 0.269517011 -0.122847121 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0035861///site of double-strand break+++GO:0090734///site of DNA damage GO:0002039///p53 binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097371///MDM2/MDM4 family protein binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0016567///protein ubiquitination+++GO:0031052///chromosome breakage+++GO:0031297///replication fork processing+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0036297///interstrand cross-link repair+++GO:2000001///regulation of DNA damage checkpoint 234740 234740 'Tmem231' mRNA 1244 1092 1220 23.15 20.04 24.13 7.14 7.58 7.37 22.44 7.363333333 439 455 436 1185.333333 443.3333333 1.88E-41 -1.43259701 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0001944///vasculature development+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0032880///regulation of protein localization+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0060271///cilium assembly+++GO:0060563///neuroepithelial cell differentiation 234776 234776 'Atmin' mRNA 534 592 481 5.97 6.5 5.71 4.69 3.72 4.52 6.06 4.31 482 374 450 535.6666667 435.3333333 0.02252116 -0.30973101 GO:0005634///nucleus+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0070840///dynein complex binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010628///positive regulation of gene expression+++GO:0044458///motile cilium assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902857///positive regulation of non-motile cilium assembly" 234779 234779 'Plcg2' mRNA 75 104 73 0.93 1.28 0.97 7.7 6.41 7.25 1.06 7.12 711 578 648 84 645.6666667 7.42E-74 2.932179873 "00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04020///Calcium signaling pathway+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04066///HIF-1 signaling pathway+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05214///Glioma+++05223///Non-small cell lung cancer+++05225///Hepatocellular carcinoma" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097708///intracellular vesicle GO:0001784///phosphotyrosine residue binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0097110///scaffold protein binding+++GO:0140031///phosphorylation-dependent protein binding+++GO:1990782///protein tyrosine kinase binding "GO:0001775///cell activation+++GO:0001878///response to yeast+++GO:0002092///positive regulation of receptor internalization+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002224///toll-like receptor signaling pathway+++GO:0002281///macrophage activation involved in immune response+++GO:0002316///follicular B cell differentiation+++GO:0002732///positive regulation of dendritic cell cytokine production+++GO:0006629///lipid metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009395///phospholipid catabolic process+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016042///lipid catabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0019722///calcium-mediated signaling+++GO:0030183///B cell differentiation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032026///response to magnesium ion+++GO:0032237///activation of store-operated calcium channel activity+++GO:0032481///positive regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032747///positive regulation of interleukin-23 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0033198///response to ATP+++GO:0035556///intracellular signal transduction+++GO:0043069///negative regulation of programmed cell death+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0048678///response to axon injury+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061760///antifungal innate immune response+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0071277///cellular response to calcium ion+++GO:0071396///cellular response to lipid+++GO:0150078///positive regulation of neuroinflammatory response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1990858///cellular response to lectin" 234796 234796 'Klhl36' mRNA 394 419 425 10.4 10.89 11.9 10.76 10.15 11.85 11.06333333 10.92 469 432 500 412.6666667 467 0.265476503 0.164966857 GO:0097602///cullin family protein binding GO:0016567///protein ubiquitination 234797 234797 '6430548M08Rik' mRNA 505 553 280 4.85 5.23 2.86 2.73 3.14 3.66 4.313333333 3.176666667 311 357 424 446 364 0.189724006 -0.289633349 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234814 234814 'Mthfsd' mRNA 914.57 882.87 957.53 16.65 15.56 18.64 14.77 15.35 15.29 16.95 15.13666667 853.01 837.93 837.97 918.3233333 842.97 0.222634964 -0.137690253 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding 234825 234825 'Klhdc4' mRNA 346 363 356 10.14 10.11 11.07 13.61 14.89 17.04 10.44 15.18 570 574 632 355 592 3.22E-09 0.725945425 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234836 234836 'Il17c' mRNA 12 5 4 0.44 0.26 0.14 0.31 0.2 0.12 0.28 0.21 11 7 4 7 7.333333333 0.965493435 0.059774515 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0030223///neutrophil differentiation+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 234839 234839 'Piezo1' mRNA 713.98 667.39 427.77 5.28 5.34 4.2 8.94 8.28 8.25 4.94 8.49 1069.75 952.12 1005.08 603.0466667 1008.983333 4.57E-08 0.740417406 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042995///cell projection GO:0005261///cation channel activity+++GO:0005515///protein binding+++GO:0008381///mechanosensitive ion channel activity+++GO:0042802///identical protein binding+++GO:0140135///mechanosensitive cation channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0010831///positive regulation of myotube differentiation+++GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050982///detection of mechanical stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0098655///cation transmembrane transport 234847 234847 'Spg7' mRNA 353 385 194 7.66 8.22 4.47 6.76 7.06 6.96 6.783333333 6.926666667 359 366 357 310.6666667 360.6666667 0.333185359 0.216702652 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005745///m-AAA complex+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007005///mitochondrion organization+++GO:0007155///cell adhesion+++GO:0008053///mitochondrial fusion+++GO:0008089///anterograde axonal transport+++GO:0030155///regulation of cell adhesion+++GO:0034982///mitochondrial protein processing+++GO:0042407///cristae formation+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0065003///protein-containing complex assembly+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death 234852 234852 'Chmp1a' mRNA 2769 2774 2808 72 71.04 77.45 83.73 82.24 81.76 73.49666667 82.57666667 3703 3551 3500 2783.666667 3584.666667 9.79E-08 0.351629814 04144///Endocytosis+++04217///Necroptosis GO:0000794///condensed nuclear chromosome+++GO:0000815///ESCRT III complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005771///multivesicular body+++GO:0005815///microtubule organizing center+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016363///nuclear matrix GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016458///gene silencing+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0045324///late endosome to vacuole transport+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0061952///midbody abscission+++GO:1901673///regulation of mitotic spindle assembly" 234854 234854 'Cdk10' mRNA 839 830 825 29.98 29.32 31.26 21.29 18.61 19.33 30.18666667 19.74333333 687 587 604 831.3333333 626 5.20E-05 -0.422790298 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0097472///cyclin-dependent protein kinase activity GO:0006468///protein phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030030///cell projection organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043410///positive regulation of MAPK cascade+++GO:1902018///negative regulation of cilium assembly 234857 234857 'Spire2' mRNA 205 212 169 4.93 5.02 4.31 2.38 3.42 2.31 4.753333333 2.703333333 114 160 107 195.3333333 127 0.005811646 -0.626459905 04320///Dorso-ventral axis formation GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow GO:0003674///molecular_function+++GO:0003779///actin binding GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0036089///cleavage furrow formation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0045010///actin nucleation+++GO:0046907///intracellular transport+++GO:0048193///Golgi vesicle transport+++GO:0051295///establishment of meiotic spindle localization+++GO:0051639///actin filament network formation+++GO:0070649///formin-nucleated actin cable assembly+++GO:2000781///positive regulation of double-strand break repair 234865 234865 'Nup133' mRNA 599 593 564 5.48 5.33 5.47 5.6 4.95 5.76 5.426666667 5.436666667 705 609 703 585.3333333 672.3333333 0.114042153 0.187754959 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005694///chromosome+++GO:0031080///nuclear pore outer ring+++GO:0031965///nuclear membrane" GO:0017056///structural constituent of nuclear pore GO:0000972///transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006999///nuclear pore organization+++GO:0015031///protein transport+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0021915///neural tube development+++GO:0022008///neurogenesis+++GO:0048339///paraxial mesoderm development+++GO:0051028///mRNA transport+++GO:0061053///somite development+++GO:0072006///nephron development 234875 234875 'Ttc13' mRNA 440 409 424 7.97 7.4 8.35 11.63 11.36 11.61 7.906666667 11.53333333 739 706 712 424.3333333 719 1.09E-11 0.748078964 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 234878 234878 'Map3k21' mRNA 130 156 101 1.31 1.49 1.11 0.95 1.1 1.31 1.303333333 1.12 98 116 129 129 114.3333333 0.560045685 -0.17718484 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation 234889 234889 'Gucy1a2' mRNA 68 41 30 0.39 0.24 0.12 0.09 0.18 0.17 0.25 0.146666667 27 19 29 46.33333333 25 0.064619712 -0.894269401 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04970///Salivary secretion GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004383///guanylate cyclase activity+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0020037///heme binding+++GO:0044877///protein-containing complex binding GO:0006182///cGMP biosynthetic process+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010750///positive regulation of nitric oxide mediated signal transduction+++GO:0035556///intracellular signal transduction 234911 234911 'Mmp27' mRNA 0 1 0 0 0.03 0 2.86 3.02 2.53 0.01 2.803333333 124 128 106 0.333333333 119.3333333 2.27E-11 8.368091985 GO:0031012///extracellular matrix+++GO:0042406///extrinsic component of endoplasmic reticulum membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process 234912 234912 'Cfap300' mRNA 358 371 359 12.96 13.18 13.7 5.99 5.8 5.21 13.28 5.666666667 191 178 160 362.6666667 176.3333333 9.30E-12 -1.053041686 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 234915 234915 'Cep126' mRNA 581.05 601 452 2.85 2.81 2.82 0.86 0.84 0.63 2.826666667 0.776666667 162 149 145.46 544.6833333 152.1533333 2.62E-36 -1.8484021 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0003674///molecular_function GO:0007052///mitotic spindle organization+++GO:0031122///cytoplasmic microtubule organization+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 234959 234959 'Med17' mRNA 707.51 735.51 681.51 9.13 9.2 9.27 8.3 9.84 8.86 9.2 9 716.72 834.08 736.67 708.1766667 762.49 0.460770217 0.096965375 04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 234964 234964 'Deup1' mRNA 2 3 1 0.05 0.07 0.04 0.28 0.18 0.17 0.053333333 0.21 16 9 10 2 11.66666667 0.021224757 2.537366665 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0098536///deuterosome GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007099///centriole replication+++GO:0030030///cell projection organization+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation+++GO:1903251///multi-ciliated epithelial cell differentiation 234967 234967 'Slc36a4' mRNA 434 499 457 4.15 4.7 4.64 4.97 5.14 4.89 4.496666667 5 597 605 569 463.3333333 590.3333333 0.005446001 0.338072495 04974///Protein digestion and absorption GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015196///L-tryptophan transmembrane transporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015808///L-alanine transport+++GO:0015824///proline transport+++GO:0015827///tryptophan transport+++GO:0035524///proline transmembrane transport 234988 234988 'Mbd3l2' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 235028 235028 'Zfp426' mRNA 618 660 563 9.61 10.12 9.25 6.66 6.3 6.3 9.66 6.42 494 453 453 613.6666667 466.6666667 3.87E-04 -0.405257744 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 235036 235036 'Ppan' mRNA 342 285 337 11.91 9.78 12.45 12.52 13.48 14.19 11.38 13.39666667 413 434 453 321.3333333 433.3333333 0.005360856 0.417660579 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor" GO:0019843///rRNA binding GO:0000027///ribosomal large subunit assembly+++GO:0001560///regulation of cell growth by extracellular stimulus+++GO:0006364///rRNA processing 235040 235040 'Atg4d' mRNA 894.61 952.81 916.33 22.67 23.13 24.51 17.38 17.82 17 23.43666667 17.4 826.88 786.51 738.98 921.25 784.1233333 0.015409182 -0.24564266 04136///Autophagy - other+++04140///Autophagy - animal GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0015031///protein transport 235041 235041 'Kank2' mRNA 503 597 427 5.54 6.47 4.99 8.37 7.18 8.41 5.666666667 7.986666667 874 733 851 509 819.3333333 1.57E-08 0.678926787 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043069///negative regulation of programmed cell death+++GO:0051497///negative regulation of stress fiber assembly+++GO:0070563///negative regulation of vitamin D receptor signaling pathway+++GO:0072073///kidney epithelium development+++GO:0090521///glomerular visceral epithelial cell migration+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 235043 235043 'Tmem205' mRNA 1339 1322 1262 109.41 110.39 112.17 109.71 115.57 114.17 110.6566667 113.15 1524 1572 1520 1307.666667 1538.666667 0.005916997 0.223715505 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 235044 235044 'Plppr2' mRNA 462 567 406 7.89 9.77 7.42 7.39 7.96 7.72 8.36 7.69 460 465 462 478.3333333 462.3333333 0.754495413 -0.055646316 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042577///lipid phosphatase activity GO:0006644///phospholipid metabolic process+++GO:0007165///signal transduction+++GO:0016311///dephosphorylation+++GO:0046839///phospholipid dephosphorylation 235047 235047 'Zfp809' mRNA 535 495 497 20.2 18.2 19.65 20.91 18.6 20.37 19.35 19.96 641 557 592 509 596.6666667 0.079568898 0.216364166 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045087///innate immune response+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate" 235048 235048 'Zfp599' mRNA 47 60 44 0.7 0.9 0.7 0.81 1.1 1.07 0.766666667 0.993333333 62 83 79 50.33333333 74.66666667 0.104730084 0.563613738 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 235050 235050 'Zfp810' mRNA 472 524 465 7.4 8 7.75 5.83 5.98 5.92 7.716666667 5.91 451 456 439 487 448.6666667 0.360732122 -0.128788882 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 235072 235072 'Septin7' mRNA 2602 2634 2817 57.67 57.42 66.17 86.22 85.28 85.67 60.42 85.72333333 4483 4323 4308 2684.333333 4371.333333 5.28E-22 0.688860002 05131///Shigellosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0005938///cell cortex+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030496///midbody+++GO:0031105///septin complex+++GO:0031514///motile cilium+++GO:0032153///cell division site+++GO:0032154///cleavage furrow+++GO:0032156///septin cytoskeleton+++GO:0032160///septin filament array+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0043679///axon terminus+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0097227///sperm annulus+++GO:0097730///non-motile cilium+++GO:0098978///glutamatergic synapse" GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0060090///molecular adaptor activity GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0016476///regulation of embryonic cell shape+++GO:0030154///cell differentiation+++GO:0030865///cortical cytoskeleton organization+++GO:0031270///pseudopodium retraction+++GO:0034613///cellular protein localization+++GO:0048668///collateral sprouting+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0099173///postsynapse organization+++GO:1902857///positive regulation of non-motile cilium assembly 235086 235086 'Igsf9b' mRNA 959 998 549 6.15 6.25 1.87 1.5 2.55 2.34 4.756666667 2.13 504 605 603 835.3333333 570.6666667 0.001162453 -0.547161956 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098982///GABA-ergic synapse+++GO:0099629///postsynaptic specialization of symmetric synapse GO:0019900///kinase binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0099560///synaptic membrane adhesion 235106 235106 'Ntm' mRNA 320 284 241.9 5.38 4.7 4.35 0.68 0.47 0.66 4.81 0.603333333 47 33 44 281.9666667 41.33333333 6.78E-35 -2.778046496 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse GO:0007155///cell adhesion+++GO:0010977///negative regulation of neuron projection development 235130 235130 'Adamts15' mRNA 49 63 53 0.44 0.61 0.5 0.28 0.3 0.18 0.516666667 0.253333333 33 33 22 55 29.33333333 0.02388072 -0.917974926 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding GO:0006508///proteolysis+++GO:0007520///myoblast fusion+++GO:0022617///extracellular matrix disassembly+++GO:0030198///extracellular matrix organization 235132 235132 'Zbtb44' mRNA 699.2 702.27 385.98 4.22 4.16 2.43 2.82 2.43 3.27 3.603333333 2.84 542.37 455.02 607.56 595.8166667 534.9833333 0.465592776 -0.155321449 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 235134 235134 'Nfrkb' mRNA 666 582 649 6.69 5.82 6.96 4.03 4.22 4.22 6.49 4.156666667 461 471 468 632.3333333 466.6666667 2.28E-04 -0.451787707 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex GO:0002020///protease binding+++GO:0003677///DNA binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008150///biological_process 235135 235135 'Tmem45b' mRNA 649.53 596.43 468.74 13.58 12.33 10.44 6.36 5.69 6.4 12.11666667 6.15 348.67 298.61 335.74 571.5666667 327.6733333 2.04E-09 -0.811775221 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 235169 235169 'Foxred1' mRNA 714 855 741 16 19.11 17.78 16.26 17.2 16.54 17.63 16.66666667 805 827 786 770 806 0.688295718 0.055534789 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0016491///oxidoreductase activity GO:0032981///mitochondrial respiratory chain complex I assembly 235180 235180 'Fez1' mRNA 894 985 859 29.68 32.39 30.94 22.74 23.02 22.94 31.00333333 22.9 782 769 761 912.6666667 770.6666667 0.009431435 -0.254255663 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0047485///protein N-terminus binding GO:0010976///positive regulation of neuron projection development+++GO:0021766///hippocampus development+++GO:0030010///establishment of cell polarity+++GO:0045666///positive regulation of neuron differentiation+++GO:0051654///establishment of mitochondrion localization+++GO:0061881///positive regulation of anterograde axonal transport of mitochondrion+++GO:0070584///mitochondrion morphogenesis+++GO:0071363///cellular response to growth factor stimulus+++GO:1902902///negative regulation of autophagosome assembly 235184 235184 'Msantd2' mRNA 1622.76 1475.36 1430.46 5.88 4.84 5.29 4.05 3.66 3.84 5.336666667 3.85 1464.92 1213.44 1258.42 1509.526667 1312.26 0.021444932 -0.214884147 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 235281 235281 'Scn3b' mRNA 911 919 872 11.98 11.87 12.29 1.72 1.6 1.88 12.04666667 1.733333333 154 139 159 900.6666667 150.6666667 2.46E-99 -2.591475899 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc GO:0005244///voltage-gated ion channel activity+++GO:0005272///sodium channel activity+++GO:0017080///sodium channel regulator activity+++GO:0019871///sodium channel inhibitor activity+++GO:0044325///ion channel binding+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007399///nervous system development+++GO:0010460///positive regulation of heart rate+++GO:0010765///positive regulation of sodium ion transport+++GO:0019233///sensory perception of pain+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051899///membrane depolarization+++GO:0060048///cardiac muscle contraction+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0061337///cardiac conduction+++GO:0072659///protein localization to plasma membrane+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086010///membrane depolarization during action potential+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086015///SA node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:2000649///regulation of sodium ion transmembrane transporter activity 235283 235283 'Gramd1b' mRNA 1221.01 1195.8 1082.24 9.04 9.31 9.43 10.34 8.02 8.67 9.26 9.01 1374.56 1028.13 1146.46 1166.35 1183.05 0.956791226 0.007817474 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001786///phosphatidylserine binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0070300///phosphatidic acid binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0042632///cholesterol homeostasis+++GO:0071397///cellular response to cholesterol+++GO:0120009///intermembrane lipid transfer 235293 235293 'Sc5d' mRNA 1732 1617 1455 35.07 32.11 31.4 24.91 27.37 25.28 32.86 25.85333333 1351 1378 1297 1601.333333 1342 0.00154086 -0.264271742 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000248///C-5 sterol desaturase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0050046///lathosterol oxidase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0033490///cholesterol biosynthetic process via lathosterol 235300 235300 'Tlcd5' mRNA 147.02 166.53 151.32 1.99 2.3 2.27 1.95 1.94 1.94 2.186666667 1.943333333 165.05 161.67 151.08 154.9566667 159.2666667 0.912891136 0.028382217 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 235312 235312 'C1qtnf5' mRNA 68.44 81.97 15.99 2.95 3.35 0.69 3.27 12.11 9.11 2.33 8.163333333 87.3 303.3 227.35 55.46666667 205.9833333 0.026921698 1.939585129 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030133///transport vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0042802///identical protein binding GO:0007601///visual perception+++GO:0009306///protein secretion+++GO:0042462///eye photoreceptor cell development+++GO:0048839///inner ear development+++GO:0060041///retina development in camera-type eye 235315 235315 'Rnf214' mRNA 2133.26 2197.62 2082.96 15.64 15.56 15.85 11.62 10.83 11.25 15.68333333 11.23333333 1839.13 1614.41 1633.55 2137.946667 1695.696667 2.97E-06 -0.346936293 GO:0005575///cellular_component GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination 235320 235320 'Zbtb16' mRNA 936 945 759 6.47 6.42 5.56 8.1 6.05 6.89 6.15 7.013333333 1351 985 1113 880 1149.666667 0.001125491 0.375106529 05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001823///mesonephros development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0009880///embryonic pattern specification+++GO:0009952///anterior/posterior pattern specification+++GO:0030097///hemopoiesis+++GO:0030326///embryonic limb morphogenesis+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0034504///protein localization to nucleus+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0043931///ossification involved in bone maturation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0045778///positive regulation of ossification+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048133///male germ-line stem cell asymmetric division+++GO:0051138///positive regulation of NK T cell differentiation+++GO:0051216///cartilage development+++GO:0061036///positive regulation of cartilage development" 235323 235323 'Usp28' mRNA 338 412 429 4.3 5.16 5.8 4.04 3.55 4 5.086666667 3.863333333 365 313 351 393 343 0.213280474 -0.212406246 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007265///Ras protein signal transduction+++GO:0008283///cell proliferation+++GO:0010212///response to ionizing radiation+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability+++GO:0034644///cellular response to UV+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 235330 235330 'Ttc12' mRNA 320 344 323 7.4 8.01 7.94 6.93 6.35 6.78 7.783333333 6.686666667 327 293 318 329 312.6666667 0.640356316 -0.085725878 GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0003674///molecular_function GO:0007288///sperm axoneme assembly+++GO:0030030///cell projection organization+++GO:0070286///axonemal dynein complex assembly 235339 235339 'Dlat' mRNA 1635 1658 1569 21.86 21.81 22.25 19.38 18.59 18.9 21.97333333 18.95666667 1668 1563 1576 1620.666667 1602.333333 0.780148441 -0.02825374 00010///Glycolysis / Gluconeogenesis+++00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045254///pyruvate dehydrogenase complex "GO:0004742///dihydrolipoyllysine-residue acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030523///dihydrolipoamide S-acyltransferase activity+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0042802///identical protein binding" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006090///pyruvate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0030431///sleep+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate 235344 235344 'Sik2' mRNA 1287.02 1306.35 942.26 12.12 12.14 9.22 7.03 5.78 5.87 11.16 6.226666667 852.45 755.14 717.59 1178.543333 775.06 3.99E-08 -0.61152564 04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0008286///insulin receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046777///protein autophosphorylation 235345 235345 'Hoatz' mRNA 0 1 4 0 0.09 0.21 0 0 0.11 0.1 0.036666667 0 0 2 1.666666667 0.666666667 0.683099624 -1.374957038 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0035082///axoneme assembly+++GO:0060271///cilium assembly 235379 235379 'Gldn' mRNA 2163 2201 2140 24.93 24.95 26.17 14.96 12.88 13.68 25.35 13.84 1494 1257 1323 2168 1358 8.31E-19 -0.688414263 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0032528///microvillus organization+++GO:0034113///heterotypic cell-cell adhesion+++GO:0045162///clustering of voltage-gated sodium channels 235380 235380 'Dmxl2' mRNA 1674 1703 1064 8.23 8.2 5.55 3.94 4.61 4.56 7.326666667 4.37 921 1056 1036 1480.333333 1004.333333 1.98E-05 -0.559989955 04142///Lysosome GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043291///RAVE complex+++GO:0045202///synapse+++GO:0098992///neuronal dense core vesicle GO:0031267///small GTPase binding GO:0007035///vacuolar acidification+++GO:0007268///chemical synaptic transmission+++GO:0007283///spermatogenesis+++GO:0007608///sensory perception of smell+++GO:0042593///glucose homeostasis 235386 235386 'Hykk' mRNA 127.03 123.93 123.51 1.33 1.27 1.37 1.12 1.22 1.23 1.323333333 1.19 123.58 131.01 131.29 124.8233333 128.6266667 0.903678305 0.034266793 00310///Lysine degradation GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019202///amino acid kinase activity+++GO:0047992///hydroxylysine kinase activity GO:0016310///phosphorylation 235402 235402 'Lingo1' mRNA 8 6 3 0.1 0.08 0.05 0.05 0.02 0.05 0.076666667 0.04 3 1 3 5.666666667 2.333333333 0.380224621 -1.282896941 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding GO:0021954///central nervous system neuron development+++GO:0031175///neuron projection development+++GO:0043491///protein kinase B signaling+++GO:0048715///negative regulation of oligodendrocyte differentiation 235406 235406 'Snx33' mRNA 1196 1261 1214 14.06 14.57 15.15 8.93 8.8 7.54 14.59333333 8.423333333 875 841 713 1223.666667 809.6666667 6.12E-10 -0.608548493 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007032///endosome organization+++GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0017038///protein import+++GO:0036089///cleavage furrow formation+++GO:0044351///macropinocytosis+++GO:0045806///negative regulation of endocytosis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051301///cell division+++GO:0097320///plasma membrane tubulation+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2000010///positive regulation of protein localization to cell surface 235415 235415 'Cplx3' mRNA 0 0 1 0 0 0.02 0.02 0 0.02 0.006666667 0.013333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873488313 04721///Synaptic vesicle cycle GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031201///SNARE complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0098993///anchored component of synaptic vesicle membrane+++GO:0099029///anchored component of presynaptic active zone membrane GO:0000149///SNARE binding+++GO:0005326///neurotransmitter transporter activity+++GO:0005537///mannose binding+++GO:0019905///syntaxin binding+++GO:0030246///carbohydrate binding GO:0006836///neurotransmitter transport+++GO:0006887///exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007601///visual perception+++GO:0016079///synaptic vesicle exocytosis+++GO:0030073///insulin secretion+++GO:0031630///regulation of synaptic vesicle fusion to presynaptic active zone membrane+++GO:0046928///regulation of neurotransmitter secretion+++GO:0050896///response to stimulus 235416 235416 'Lman1l' mRNA 0 1 0 0 0.03 0 0 0.03 0 0.01 0.01 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0005537///mannose binding+++GO:0030246///carbohydrate binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization 235431 235431 'Coro2b' mRNA 232 260 188 3.81 4.11 3.22 2.02 2.25 2.07 3.713333333 2.113333333 142 154 146 226.6666667 147.3333333 0.001168586 -0.627311488 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0016020///membrane GO:0003779///actin binding+++GO:0017166///vinculin binding+++GO:0051015///actin filament binding+++GO:1990147///talin binding GO:0003093///regulation of glomerular filtration+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0030036///actin cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0048041///focal adhesion assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0080135///regulation of cellular response to stress+++GO:1904950///negative regulation of establishment of protein localization+++GO:1904951///positive regulation of establishment of protein localization 235435 235435 'Lctl' mRNA 38.96 36.66 46.64 1.01 0.96 1.29 0.89 0.65 0.52 1.086666667 0.686666667 39.36 27.41 22.35 40.75333333 29.70666667 0.351001174 -0.468421944 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008422///beta-glucosidase activity" GO:0002089///lens morphogenesis in camera-type eye+++GO:0005975///carbohydrate metabolic process+++GO:0007601///visual perception+++GO:0050896///response to stimulus 235439 235439 'Herc1' mRNA 2102.15 2171.99 2014.36 7.16 7.29 7.31 8.36 7.1 7.42 7.253333333 7.626666667 2826.33 2339.33 2435.52 2096.166667 2533.726667 8.04E-04 0.260793763 04120///Ubiquitin mediated proteolysis GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004842///ubiquitin-protein transferase activity GO:0010507///negative regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0031175///neuron projection development+++GO:0050885///neuromuscular process controlling balance 235441 235441 'Usp3' mRNA 1428 1319.22 1348.37 12.5 11.15 12.47 10.33 10.65 9.87 12.04 10.28333333 1391.14 1360.66 1351.11 1365.196667 1367.636667 0.928752297 -0.009954378 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0090543///Flemming body GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability 235442 235442 'Rab8b' mRNA 919 964 1001 10.35 10.68 11.96 24.05 22.92 25.35 10.99666667 24.10666667 2458 2291 2510 961.3333333 2419.666667 1.47E-58 1.317745595 04530///Tight junction GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005778///peroxisomal membrane+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0030911///TPR domain binding GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0019882///antigen processing and presentation+++GO:0031346///positive regulation of cell projection organization+++GO:0032869///cellular response to insulin stimulus+++GO:0045046///protein import into peroxisome membrane+++GO:0048210///Golgi vesicle fusion to target membrane+++GO:0051461///positive regulation of corticotropin secretion+++GO:0072659///protein localization to plasma membrane 235459 235459 'Gtf2a2' mRNA 803 778 816 57.91 56.26 63.2 64.72 66.19 61.1 59.12333333 64.00333333 1013 1013 933 799 986.3333333 0.004195721 0.29061447 03022///Basal transcription factors+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005672///transcription factor TFIIA complex+++GO:0030054///cell junction GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly 235461 235461 'Mindy2' mRNA 886.09 921.44 759 7.57 7.1 6.46 6.58 6.71 7.14 7.043333333 6.81 1041.18 993.07 1096 855.51 1043.416667 0.004176834 0.277919558 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016807///cysteine-type carboxypeptidase activity+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0071795///K11-linked polyubiquitin modification-dependent protein binding+++GO:0071796///K6-linked polyubiquitin modification-dependent protein binding+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0071108///protein K48-linked deubiquitination 235469 235469 'Zfp280d' mRNA 646 677 613 7.91 8.12 7.92 5.71 5.58 4.98 7.983333333 5.423333333 537 514 454 645.3333333 501.6666667 0.001257637 -0.374499924 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 235472 235472 'Prtg' mRNA 292 301 293 1.75 1.77 1.86 0.54 0.53 0.62 1.793333333 0.563333333 104 100 115 295.3333333 106.3333333 6.56E-17 -1.485874683 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0050768///negative regulation of neurogenesis+++GO:0070593///dendrite self-avoidance 235493 235493 'Fam214a' mRNA 900 965 906 11.58 12.25 12.59 6.57 6.05 6.12 12.14 6.246666667 581 527 533 923.6666667 547 6.59E-15 -0.768192935 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 235497 235497 'Leo1' mRNA 672.89 627.87 688.4 16.73 15.4 18.1 16.89 16.49 16.07 16.74333333 16.48333333 818.91 784.67 760.34 663.0533333 787.9733333 0.038626657 0.235180802 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016593///Cdc73/Paf1 complex GO:0005515///protein binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding GO:0001711///endodermal cell fate commitment+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006378///mRNA polyadenylation+++GO:0010390///histone monoubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0016570///histone modification+++GO:0019827///stem cell population maintenance+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033523///histone H2B ubiquitination+++GO:0045638///negative regulation of myeloid cell differentiation 235504 235504 'Slc17a5' mRNA 589.92 558.66 600.85 9.7 9.09 10.49 11.53 11.63 11.64 9.76 11.6 795.63 787.92 782.93 583.1433333 788.8266667 9.00E-05 0.422888824 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0015136///sialic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006820///anion transport+++GO:0006865///amino acid transport+++GO:0009617///response to bacterium+++GO:0015739///sialic acid transport+++GO:0055085///transmembrane transport 235505 235505 'Cd109' mRNA 10 9 3 0.09 0.08 0.03 2.11 1.84 1.86 0.066666667 1.936666667 269 229 229 7.333333333 242.3333333 2.74E-41 5.037855641 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0050431///transforming growth factor beta binding GO:0001933///negative regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0010466///negative regulation of peptidase activity+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0045616///regulation of keratinocyte differentiation+++GO:0061045///negative regulation of wound healing+++GO:0072675///osteoclast fusion 235527 235527 'Plscr4' mRNA 183 168 183 3.07 2.77 3.27 2.42 2.86 2.62 3.036666667 2.633333333 166 191 172 178 176.3333333 0.919225401 -0.025885082 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017128///phospholipid scramblase activity+++GO:0019899///enzyme binding+++GO:0042609///CD4 receptor binding GO:0017121///phospholipid scrambling+++GO:0071222///cellular response to lipopolysaccharide 235533 235533 'Gk5' mRNA 321 280 267 3.32 2.79 2.93 1.87 1.86 1.57 3.013333333 1.766666667 219 205 179 289.3333333 201 0.001660811 -0.536591159 GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0016310///phosphorylation+++GO:0019563///glycerol catabolic process+++GO:0046167///glycerol-3-phosphate biosynthetic process 235534 235534 'Pxylp1' mRNA 749 769 818 13.79 13.91 15.99 7.36 8.48 7.23 14.56333333 7.69 458 520 438 778.6666667 472 1.03E-09 -0.735530849 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006024///glycosaminoglycan biosynthetic process+++GO:0010909///positive regulation of heparan sulfate proteoglycan biosynthetic process+++GO:0016311///dephosphorylation+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process 235542 235542 'Ppp2r3a' mRNA 883 856 811 6.86 6.33 6.68 3.24 3.07 3.04 6.623333333 3.116666667 488.16 462 455.73 850 468.63 5.92E-18 -0.871359878 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex "GO:0005509///calcium ion binding+++GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging" GO:0001754///eye photoreceptor cell differentiation+++GO:0006470///protein dephosphorylation+++GO:0007525///somatic muscle development+++GO:0045732///positive regulation of protein catabolic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090249///regulation of cell motility involved in somitogenic axis elongation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 235559 235559 'Topbp1' mRNA 147 119 87 1.53 1.22 0.96 2.27 2.04 2.49 1.236666667 2.266666667 250 222 266 117.6666667 246 3.54E-07 1.058188132 03440///Homologous recombination GO:0000794///condensed nuclear chromosome+++GO:0000922///spindle pole+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0042802///identical protein binding GO:0006270///DNA replication initiation+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007131///reciprocal meiotic recombination+++GO:0010212///response to ionizing radiation+++GO:0033314///mitotic DNA replication checkpoint 235567 235567 'Dnajc13' mRNA 544 531 481 4.61 4.32 4.52 7.01 6.27 6.96 4.483333333 6.746666667 881 804 895 518.6666667 860 1.40E-12 0.718870858 GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071203///WASH complex GO:0003674///molecular_function GO:0006898///receptor-mediated endocytosis+++GO:0007032///endosome organization+++GO:1902954///regulation of early endosome to recycling endosome transport+++GO:2000641///regulation of early endosome to late endosome transport 235574 235574 'Atp2c1' mRNA 2205 2494 2372 25.06 27.3 27.89 21.19 22.69 22.08 26.75 21.98666667 2128 2248 2189 2357 2188.333333 0.177235328 -0.118951982 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030173///integral component of Golgi membrane+++GO:0032580///Golgi cisterna membrane+++GO:0033106///cis-Golgi network membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015410///manganese-transporting ATPase activity+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0016887///ATPase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0008544///epidermis development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030026///cellular manganese ion homeostasis+++GO:0031532///actin cytoskeleton reorganization+++GO:0032468///Golgi calcium ion homeostasis+++GO:0032472///Golgi calcium ion transport+++GO:0034220///ion transmembrane transport+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0070588///calcium ion transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0098629///trans-Golgi network membrane organization 235582 235582 'Glyctk' mRNA 116 101 116 1.48 1.28 1.6 0.51 0.51 0.54 1.453333333 0.52 45 43 46 111 44.66666667 3.23E-06 -1.327781131 "00030///Pentose phosphate pathway+++00260///Glycine, serine and threonine metabolism+++00561///Glycerolipid metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008887///glycerate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 235584 235584 'Dusp7' mRNA 220 238 216 3.74 3.99 3.9 4.75 4.78 5.59 3.876666667 5.04 321 316 366 224.6666667 334.3333333 3.36E-04 0.562885418 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade 235587 235587 'Parp3' mRNA 343 346 313 7.61 7.55 7.38 18.34 18.5 19.12 7.513333333 18.65333333 973 939 951 334 954.3333333 1.03E-48 1.504074183 03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0035861///site of double-strand break+++GO:0045171///intercellular bridge "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity" GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006471///protein ADP-ribosylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030592///DNA ADP-ribosylation+++GO:0045829///negative regulation of isotype switching+++GO:0051106///positive regulation of DNA ligation+++GO:0060236///regulation of mitotic spindle organization+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:1905662///negative regulation of telomerase RNA reverse transcriptase activity+++GO:1990166///protein localization to site of double-strand break+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 235599 235599 '6430571L13Rik' mRNA 104 108 92 2.27 2.32 2.13 0.59 0.89 0.55 2.24 0.676666667 31 46 28 101.3333333 35 1.40E-06 -1.540630477 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 235604 235604 'Camkv' mRNA 19 13 11 0.34 0.23 0.21 0.22 0.06 0.13 0.26 0.136666667 14 4 8 14.33333333 8.666666667 0.407762769 -0.74032668 GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004672///protein kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0099159///regulation of modification of postsynaptic structure 235606 235606 'Apeh' mRNA 1439 1605 1483 33.68 36.99 36.84 33.91 31.43 33.58 35.83666667 32.97333333 1667 1509 1598 1509 1591.333333 0.515169877 0.0643377 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008242///omega peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0050435///amyloid-beta metabolic process 235610 235610 'Atrip' mRNA 390 412 388 8.43 8.76 8.89 8.25 8.33 7.96 8.693333333 8.18 439 433 410 396.6666667 427.3333333 0.541743127 0.095812014 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus 235611 235611 'Plxnb1' mRNA 2816 2820 2677 18.16 18.01 19.12 10.31 9.93 10.2 18.43 10.14666667 1852 1688 1793 2771 1777.666667 2.36E-23 -0.652423174 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity+++GO:0032794///GTPase activating protein binding GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030334///regulation of cell migration+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043931///ossification involved in bone maturation+++GO:0048812///neuron projection morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0051493///regulation of cytoskeleton organization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:1904862///inhibitory synapse assembly 235623 235623 'Scap' mRNA 1855 1804 1394 23.82 22.76 18.99 13.69 13.46 13.84 21.85666667 13.66333333 1227 1174 1193 1684.333333 1198 5.09E-08 -0.498249418 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0044877///protein-containing complex binding GO:0001666///response to hypoxia+++GO:0006629///lipid metabolic process+++GO:0006955///immune response+++GO:0007568///aging+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0019217///regulation of fatty acid metabolic process+++GO:0032868///response to insulin+++GO:0032933///SREBP signaling pathway+++GO:0042304///regulation of fatty acid biosynthetic process+++GO:0044255///cellular lipid metabolic process+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0090110///cargo loading into COPII-coated vesicle 235626 235626 'Setd2' mRNA 1334 1339 1230 8.37 8.24 8.19 6.95 5.97 7.27 8.266666667 6.73 1274 1075 1301 1301 1216.666667 0.297482578 -0.10837546 00310///Lysine degradation GO:0005634///nucleus+++GO:0005694///chromosome GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001763///morphogenesis of a branching structure+++GO:0001843///neural tube closure+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0010452///histone H3-K36 methylation+++GO:0010468///regulation of gene expression+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010793///regulation of mRNA export from nucleus+++GO:0018023///peptidyl-lysine trimethylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0032259///methylation+++GO:0032465///regulation of cytokinesis+++GO:0032727///positive regulation of interferon-alpha production+++GO:0034340///response to type I interferon+++GO:0034728///nucleosome organization+++GO:0034968///histone lysine methylation+++GO:0035441///cell migration involved in vasculogenesis+++GO:0035987///endodermal cell differentiation+++GO:0045087///innate immune response+++GO:0048332///mesoderm morphogenesis+++GO:0048568///embryonic organ development+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048863///stem cell differentiation+++GO:0048864///stem cell development+++GO:0051607///defense response to virus+++GO:0060039///pericardium development+++GO:0060669///embryonic placenta morphogenesis+++GO:0060977///coronary vasculature morphogenesis+++GO:0097198///histone H3-K36 trimethylation+++GO:0097676///histone H3-K36 dimethylation+++GO:1902850///microtubule cytoskeleton organization involved in mitosis+++GO:1905634///regulation of protein localization to chromatin" 235627 235627 'Nbeal2' mRNA 482 546 494 2.87 3.2 3.12 3.6 2.9 3.12 3.063333333 3.206666667 695 547 584 507.3333333 608.6666667 0.056628579 0.249457787 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane GO:0019901///protein kinase binding GO:0007596///blood coagulation+++GO:0008104///protein localization+++GO:0030220///platelet formation+++GO:0035855///megakaryocyte development+++GO:0042060///wound healing+++GO:0070889///platelet alpha granule organization 235628 235628 'Prss42' mRNA 2 3 4 0.08 0.11 0.16 0 0 0 0.116666667 0 0 0 0 3 0 0.098203731 -4.050968426 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 235631 235631 'Prss50' mRNA 449 483 438 18.61 19.88 19.4 6.19 4.92 4.7 19.29666667 5.27 172 133 128 456.6666667 144.3333333 3.83E-27 -1.674626666 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 235633 235633 'Als2cl' mRNA 791 735 684 8.81 8.1 8.17 6.97 6.86 6.79 8.36 6.873333333 711 683 667 736.6666667 687 0.346900561 -0.111314486 GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0007032///endosome organization+++GO:0008104///protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 235634 235634 'Fam240a' mRNA 0 0 2 0 0 0.2 0 0 0 0.066666667 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 235636 235636 'Rtp3' mRNA 11 5 3 0.25 0.11 0.07 0.32 0.17 0.23 0.143333333 0.24 16 9 12 6.333333333 12.33333333 0.323017495 0.956957012 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031849///olfactory receptor binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006612///protein targeting to membrane+++GO:0051205///protein insertion into membrane 235661 235661 'Dync1li1' mRNA 1215 1205.13 1195 33.73 32.95 35.19 23.44 23.49 24.62 33.95666667 23.85 971 950 987 1205.043333 969.3333333 1.97E-04 -0.326206549 04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex" GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding+++GO:0045504///dynein heavy chain binding GO:0000226///microtubule cytoskeleton organization+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0046605///regulation of centrosome cycle+++GO:0051301///cell division+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1990090///cellular response to nerve growth factor stimulus 235674 235674 'Acaa1b' mRNA 94.65 128.38 108.66 3.71 4.98 4.52 4.14 4.38 4.26 4.403333333 4.26 121.44 126.42 121.01 110.5633333 122.9566667 0.626279592 0.146714318 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00592///alpha-Linolenic acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome" GO:0005739///mitochondrion+++GO:0005777///peroxisome "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0008775///acetate CoA-transferase activity+++GO:0016401///palmitoyl-CoA oxidase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0050633///acetyl-CoA C-myristoyltransferase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0008206///bile acid metabolic process+++GO:0010124///phenylacetate catabolic process 235682 235682 'Zfp445' mRNA 2045.78 2143.95 1867.97 16.74 17.32 16.15 13.2 12.09 11.7 16.73666667 12.33 1863.22 1663.06 1622.81 2019.233333 1716.363333 0.001466388 -0.244932012 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010216///maintenance of DNA methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071517///maintenance of imprinting at mating-type locus+++GO:2000653///regulation of genetic imprinting" 235712 235712 'Mrgpra2b' mRNA 9.63 11.4 7 0.46 0.54 0.36 0.17 0.3 0.61 0.453333333 0.36 4 7 14.1 9.343333333 8.366666667 0.92238237 -0.111087853 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway 235779 235779 'Nlrp4g' mRNA 0 0 3 0 0 0.05 0.03 0 0 0.016666667 0.01 2 0 0 1 0.666666667 0.863090843 -0.691052305 GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 235907 235907 'Zfp65' mRNA 305.05 297.28 300.74 4.09 3.82 4.27 3.01 2.71 2.97 4.06 2.896666667 263.37 234.55 251.49 301.0233333 249.8033333 0.084216479 -0.283224825 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 235956 235956 'Zfp825' mRNA 640.62 692.62 697.37 11.11 11.89 12.9 8.89 8.59 8.49 11.96666667 8.656666667 586.82 553.55 543.39 676.87 561.2533333 0.014832447 -0.284296319 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 236082 236082 'Dhrsx' mRNA 189 208 57 5.96 6.94 2.07 1.99 2.37 1.9 4.99 2.086666667 69 80 62 151.3333333 70.33333333 0.003075105 -1.093048967 GO:0005576///extracellular region GO:0016491///oxidoreductase activity GO:0010508///positive regulation of autophagy 236193 236193 'Zfp709' mRNA 161 193 191 2.19 2.58 2.75 1.97 2.4 2.36 2.506666667 2.243333333 167 199 194 181.6666667 186.6666667 0.916235181 0.027262127 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003700///DNA-binding transcription factor activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0034605///cellular response to heat+++GO:0045165///cell fate commitment+++GO:0048869///cellular developmental process+++GO:0071222///cellular response to lipopolysaccharide" 236266 236266 'Alms1' mRNA 451 411 420 2.3 2.06 2.28 1.92 1.32 1.69 2.213333333 1.643333333 434 299 371 427.3333333 368 0.16303448 -0.230771861 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0036064///ciliary basal body GO:0008017///microtubule binding+++GO:0051393///alpha-actinin binding GO:0001678///cellular glucose homeostasis+++GO:0001736///establishment of planar polarity+++GO:0006629///lipid metabolic process+++GO:0007286///spermatid development+++GO:0007605///sensory perception of sound+++GO:0016197///endosomal transport+++GO:0019722///calcium-mediated signaling+++GO:0030728///ovulation+++GO:0040015///negative regulation of multicellular organism growth+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045598///regulation of fat cell differentiation+++GO:0046548///retinal rod cell development+++GO:0046599///regulation of centriole replication+++GO:0050673///epithelial cell proliferation+++GO:0051492///regulation of stress fiber assembly+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060271///cilium assembly+++GO:0120162///positive regulation of cold-induced thermogenesis 236285 236285 'Lancl3' mRNA 53 61 50 0.73 0.83 0.73 0.24 0.38 0.51 0.763333333 0.376666667 20 31 41 54.66666667 30.66666667 0.048150148 -0.839611433 GO:0005886///plasma membrane GO:0003674///molecular_function GO:0005975///carbohydrate metabolic process 236312 236312 'Ifi209' mRNA 59.45 36.58 48 0.92 0.56 0.79 11.69 10.76 12.37 0.756666667 11.60666667 864.87 777.97 886.5 48.01 843.1133333 1.69E-127 4.130754961 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0035458///cellular response to interferon-beta 236366 236366 '5730507C01Rik' mRNA 35.38 24.92 19.75 0.87 0.64 0.51 0.77 0.73 0.46 0.673333333 0.653333333 36.04 32.48 18.17 26.68333333 28.89666667 0.8580564 0.133629894 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 236451 236451 'Phf11b' mRNA 67.43 90.35 94.67 3.3 4.27 4.97 39.6 38.45 39.79 4.18 39.28 951.75 914.38 919.43 84.15 928.52 4.30E-125 3.457981483 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 236511 236511 'Ago1' mRNA 573.5 547.41 503.96 4.17 3.91 3.88 3.3 2.53 2.74 3.986666667 2.856666667 524.78 390.41 421.41 541.6233333 445.5333333 0.033054443 -0.294594599 04361///Axon regeneration GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0016442///RISC complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070578///RISC-loading complex+++GO:1990904///ribonucleoprotein complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0035198///miRNA binding GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0010501///RNA secondary structure unwinding+++GO:0010586///miRNA metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0016525///negative regulation of angiogenesis+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 236539 236539 'Phgdh' mRNA 5500 5644 5637 168.64 170.53 183.36 198.96 198.96 203.77 174.1766667 200.5633333 7459 7281 7393 5593.666667 7377.666667 3.59E-11 0.386403427 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids" GO:0043209///myelin sheath "GO:0004617///phosphoglycerate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0051287///NAD binding" GO:0006541///glutamine metabolic process+++GO:0006544///glycine metabolic process+++GO:0006563///L-serine metabolic process+++GO:0006564///L-serine biosynthetic process+++GO:0006566///threonine metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009448///gamma-aminobutyric acid metabolic process+++GO:0010468///regulation of gene expression+++GO:0019530///taurine metabolic process+++GO:0021510///spinal cord development+++GO:0021782///glial cell development+++GO:0021915///neural tube development+++GO:0022008///neurogenesis+++GO:0031175///neuron projection development+++GO:0070314///G1 to G0 transition 236573 236573 'Gbp9' mRNA 724.65 783.6 788.61 7.82 7.93 8.66 12.74 11.07 11.76 8.136666667 11.85666667 1445.36 1231.55 1308.82 765.62 1328.576667 1.80E-16 0.781211913 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071346///cellular response to interferon-gamma 236574 236574 'Smok2b' mRNA 32.78 33.34 29.76 0.8 0.8 0.77 0.38 0.37 0.28 0.79 0.343333333 17.78 16.86 12.79 31.96 15.81 0.04659781 -1.073525426 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 236576 236576 'Spry3' mRNA 5 4 6 0.06 0.05 0.08 0.26 0.14 0.28 0.063333333 0.226666667 26 14 27 5 22.33333333 0.004193391 2.139008092 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009966///regulation of signal transduction+++GO:0043409///negative regulation of MAPK cascade+++GO:0061564///axon development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0150013///negative regulation of neuron projection arborization 236643 236643 'Sytl5' mRNA 72 84 69 0.38 0.41 0.39 0.07 0.09 0.07 0.393333333 0.076666667 12 13 17 75 14 1.44E-09 -2.430042337 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070382///exocytic vesicle GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0031267///small GTPase binding+++GO:0042043///neurexin family protein binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis 236690 236690 'Nyx' mRNA 5 11 15 0.03 0.09 0.09 0.21 0.16 0.15 0.07 0.173333333 40 27 30 10.33333333 32.33333333 0.007184391 1.620151694 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0007601///visual perception+++GO:0050896///response to stimulus 236727 236727 'Slc9a7' mRNA 628 686 567 4.11 4.44 3.96 3.11 2.87 2.34 4.17 2.773333333 501.28 443 394 627 446.0933333 5.13E-05 -0.501661235 04260///Cardiac muscle contraction GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport+++GO:1905526///regulation of Golgi lumen acidification 236732 236732 'Rbm10' mRNA 1452.24 1617.44 1461.39 24.42 26.55 26.13 18.84 18.4 18.03 25.7 18.42333333 1277.24 1214.1 1196.25 1510.356667 1229.196667 1.70E-04 -0.308524958 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0035198///miRNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008285///negative regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0034391///regulation of smooth muscle cell apoptotic process+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0070935///3'-UTR-mediated mRNA stabilization" 236733 236733 'Usp11' mRNA 1926 1979 1998 30.34 30.67 33.33 12.56 11.11 12.44 31.44666667 12.03666667 919 795 881 1967.666667 865 1.59E-46 -1.199806857 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 236781 236781 'Gpr119' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04024///cAMP signaling pathway+++04911///Insulin secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0008289///lipid binding+++GO:0031210///phosphatidylcholine binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0030073///insulin secretion 236790 236790 'Ints6l' mRNA 624 612 608 8.8 8.74 9.2 10.1 10.61 9.97 8.913333333 10.22666667 823 792 754 614.6666667 789.6666667 8.04E-04 0.34903621 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0034472///snRNA 3'-end processing 236792 236792 'Mmgt1' mRNA 633 730 661 8.3 9.42 9.2 8.5 8.72 8.31 8.973333333 8.51 746 747 706 674.6666667 733 0.384911783 0.108314875 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031901///early endosome membrane+++GO:0072546///ER membrane protein complex GO:0015087///cobalt ion transmembrane transporter activity+++GO:0015093///ferrous iron transmembrane transporter activity+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0032977///membrane insertase activity GO:0006812///cation transport+++GO:0006824///cobalt ion transport+++GO:0006825///copper ion transport+++GO:0006826///iron ion transport+++GO:0015693///magnesium ion transport+++GO:0034755///iron ion transmembrane transport+++GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1903830///magnesium ion transmembrane transport 236794 236794 'Slc9a6' mRNA 689 834 638 7.91 9.29 7.54 5.82 5.65 6.01 8.246666667 5.826666667 587 548 589 720.3333333 574.6666667 0.004559164 -0.334302946 04260///Cardiac muscle contraction GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0044308///axonal spine+++GO:0045202///synapse+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0050808///synapse organization+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0060996///dendritic spine development+++GO:0071805///potassium ion transmembrane transport+++GO:0097484///dendrite extension+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 236848 236848 'Tmem185a' mRNA 867 898 815 19.23 19.61 19.16 19.26 18 17.3 19.33333333 18.18666667 996 909 866 860 923.6666667 0.412949374 0.091575577 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 236899 236899 'Pcyt1b' mRNA 801 825 759 8.8 8.91 8.84 3.81 3.98 3.79 8.85 3.86 398 405 383 795 395.3333333 5.33E-22 -1.018636645 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0003824///catalytic activity+++GO:0004105///choline-phosphate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding GO:0001541///ovarian follicle development+++GO:0006629///lipid metabolic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0007283///spermatogenesis+++GO:0008654///phospholipid biosynthetic process+++GO:0009058///biosynthetic process 236900 236900 'Pdk3' mRNA 1751 1890 1665 30.66 32.07 31.66 22.99 23.91 25.59 31.46333333 24.16333333 1150 1128 1237 1768.666667 1171.666667 1.91E-14 -0.604223721 05415///Diabetic cardiomyopathy GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0071333///cellular response to glucose stimulus+++GO:0071398///cellular response to fatty acid+++GO:0097411///hypoxia-inducible factor-1alpha signaling pathway+++GO:2000377///regulation of reactive oxygen species metabolic process 236904 236904 'Klhl15' mRNA 291 246 212 2.86 2.24 2.08 2.72 2.15 2.59 2.393333333 2.486666667 299 229 247 249.6666667 258.3333333 0.863090843 0.038965921 GO:0005634///nucleus+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0071630///nuclear protein quality control by the ubiquitin-proteasome system+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 236915 236915 'Arhgef9' mRNA 458 398 413 4.44 3.89 4.25 2.26 1.91 2.37 4.193333333 2.18 271 225 277 423 257.6666667 7.65E-07 -0.728313077 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098690///glycinergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099572///postsynaptic specialization GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0043113///receptor clustering+++GO:0050790///regulation of catalytic activity+++GO:0099150///regulation of postsynaptic specialization assembly 236920 236920 'Stard8' mRNA 1017 1127 1089 11.07 11.93 12.42 17.61 16.46 16.79 11.80666667 16.95333333 1853 1705 1714 1077.666667 1757.333333 3.73E-17 0.692303193 GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0005096///GTPase activator activity+++GO:0008289///lipid binding GO:0007165///signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity 236930 236930 'Ercc6l' mRNA 6 12 15 0.08 0.15 0.2 0.87 0.87 0.98 0.143333333 0.906666667 78 76 85 11 79.66666667 3.80E-11 2.839356168 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0015616///DNA translocase activity+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0007049///cell cycle+++GO:0032508///DNA duplex unwinding+++GO:0051301///cell division 237010 237010 'Klhl4' mRNA 14 15 11 0.2 0.21 0.16 0.45 0.36 0.31 0.19 0.373333333 37 29 25 13.33333333 30.33333333 0.036179807 1.175943342 GO:0005575///cellular_component+++GO:0015630///microtubule cytoskeleton+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0008150///biological_process 237052 237052 'Tceal1' mRNA 618 605 526 31.66 30.62 28.62 13.35 13.25 14.69 30.3 13.76333333 299 289 318 583 302 5.32E-15 -0.958232717 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0050699///WW domain binding 237073 237073 'Rbm41' mRNA 99 89.72 116.59 1.14 0.85 1.22 1.46 1.18 1.22 1.07 1.286666667 137.52 101.78 116.07 101.77 118.4566667 0.518011257 0.200167722 GO:0005689///U12-type spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0030626///U12 snRNA binding+++GO:0097157///pre-mRNA intronic binding "GO:0000398///mRNA splicing, via spliceosome" 237082 237082 'Nxt2' mRNA 590 660 684 13.24 14.57 16.23 14.92 14.51 15.68 14.68 15.03666667 767 732 783 644.6666667 760.6666667 0.062884333 0.224376248 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0044613///nuclear pore central transport channel+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051028///mRNA transport 237091 237091 'Lhfpl1' mRNA 70 58 59 2.27 1.82 2.06 1.84 2.26 2.14 2.05 2.08 65 78 73 62.33333333 72 0.60453774 0.19835338 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 237107 237107 'Gnl3l' mRNA 2184.95 2277.72 2345.98 23.97 24.56 27.3 20.98 19.7 20.75 25.27666667 20.47666667 2201.66 2019.63 2111.47 2269.55 2110.92 0.168163274 -0.118715101 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding "GO:0031334///positive regulation of protein complex assembly+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0033234///negative regulation of protein sumoylation+++GO:0042254///ribosome biogenesis+++GO:1904816///positive regulation of protein localization to chromosome, telomeric region" 237175 237175 'Adgrg2' mRNA 70 77 65 0.81 0.87 0.79 1.21 0.96 1.07 0.823333333 1.08 122 94 104 70.66666667 106.6666667 0.036082073 0.582299331 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 237211 237211 'Fancb' mRNA 29 45 68 0.54 0.82 1.49 0.82 0.81 0.87 0.95 0.833333333 51 49 52 47.33333333 50.66666667 0.887154404 0.072501139 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0043240///Fanconi anaemia nuclear complex GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0035690///cellular response to drug+++GO:0036297///interstrand cross-link repair+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0072757///cellular response to camptothecin+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 237221 237221 'Gemin8' mRNA 300.27 297.31 332.06 10.2 10.11 11.91 7.69 7.64 6.5 10.74 7.276666667 261.02 257.22 208.46 309.88 242.2333333 0.035082245 -0.371041473 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0097504///Gemini of coiled bodies GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 237222 237222 'Ofd1' mRNA 378.19 390.77 263.64 4.01 3.89 2.77 2.1 1.89 1.85 3.556666667 1.946666667 242.01 199.5 200.59 344.2 214.0333333 7.10E-05 -0.69163106 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0043015///gamma-tubulin binding GO:0000278///mitotic cell cycle+++GO:0007099///centriole replication+++GO:0010172///embryonic body morphogenesis+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0060271///cilium assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0090307///mitotic spindle assembly+++GO:2000314///negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation 237253 237253 'Lrp11' mRNA 832 846 181 15.57 15.72 3.49 1.39 2.44 2.77 11.59333333 2.2 89 148 167 619.6666667 134.6666667 0.002392905 -2.180270009 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0051219///phosphoprotein binding GO:0006897///endocytosis+++GO:0009408///response to heat+++GO:0009409///response to cold+++GO:0009414///response to water deprivation+++GO:0009612///response to mechanical stimulus+++GO:0033555///multicellular organismal response to stress+++GO:0035902///response to immobilization stress+++GO:0042594///response to starvation 237256 237256 'Zc3h12d' mRNA 5 3 8 0.07 0.04 0.11 0.69 0.67 0.63 0.073333333 0.663333333 60 57 52 5.333333333 56.33333333 8.49E-10 3.381334692 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006402///mRNA catabolic process+++GO:0030308///negative regulation of cell growth+++GO:0042130///negative regulation of T cell proliferation+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 237300 237300 'Gm4922' mRNA 27 38 29 0.64 0.89 0.73 0.17 0.25 0.13 0.753333333 0.183333333 8 12 6 31.33333333 8.666666667 0.001870092 -1.861069306 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 237313 237313 'Il20ra' mRNA 2 0 3 0.07 0 0.11 0.18 0.07 0.29 0.06 0.18 6 3 9 1.666666667 6 0.240868497 1.812190636 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04630///JAK-STAT signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004896///cytokine receptor activity+++GO:0042015///interleukin-20 binding GO:0019221///cytokine-mediated signaling pathway+++GO:0045124///regulation of bone resorption+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 237320 237320 'Aldh8a1' mRNA 1 1 5 0.03 0.02 0.13 0 0.07 0 0.06 0.023333333 0 3 0 2.333333333 1 0.64073739 -1.255080847 00380///Tryptophan metabolism GO:0005737///cytoplasm "GO:0001758///retinal dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0047102///aminomuconate-semialdehyde dehydrogenase activity" GO:0042573///retinoic acid metabolic process+++GO:0042574///retinal metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0097053///L-kynurenine catabolic process 237336 237336 'Tbpl1' mRNA 841 910 833 16.12 17.12 16.93 11.9 13.51 13.44 16.72333333 12.95 717 793 785 861.3333333 765 0.099998054 -0.18122705 03022///Basal transcription factors+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005672///transcription factor TFIIA complex+++GO:0005737///cytoplasm GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0140223///general transcription initiation factor activity "GO:0001675///acrosome assembly+++GO:0006235///dTTP biosynthetic process+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007289///spermatid nucleus differentiation" 237339 237339 'L3mbtl3' mRNA 455 461 414 5.41 5.21 5.14 4.03 4.11 5.09 5.253333333 4.41 403 395 478 443.3333333 425.3333333 0.691360852 -0.069687439 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030099///myeloid cell differentiation+++GO:0030225///macrophage differentiation+++GO:0030851///granulocyte differentiation+++GO:0043249///erythrocyte maturation+++GO:0045892///negative regulation of transcription, DNA-templated" 237353 237353 'Sh3rf3' mRNA 12 8 12 0.11 0.08 0.13 0.04 0.02 0.02 0.106666667 0.026666667 5 2 2 10.66666667 3 0.080480263 -1.854184211 GO:0005575///cellular_component GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0046328///regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0051865///protein autoubiquitination 237360 237360 'Adamts14' mRNA 45 47 56 0.46 0.48 0.61 0.37 0.6 0.42 0.516666667 0.463333333 41 65 45 49.33333333 50.33333333 0.979105169 0.016045569 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization 237362 237362 'Npffr1' mRNA 3.46 8.01 6.02 0.04 0.08 0.07 0.1 0.08 0.08 0.063333333 0.086666667 11.11 7.73 8.1 5.83 8.98 0.607184513 0.597605654 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 237387 237387 'Lrrc3' mRNA 61.05 81.09 62.97 0.76 1 0.84 1.11 0.78 0.75 0.866666667 0.88 101.99 69.68 66.75 68.37 79.47333333 0.610386464 0.197796493 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 237397 237397 'C2cd4c' mRNA 8 2 1 0.06 0.02 0.01 0 0.01 0.01 0.03 0.006666667 0 2 1 3.666666667 1 0.371994915 -1.855036158 GO:0005829///cytosol GO:0008150///biological_process 237400 237400 'Mex3d' mRNA 42 36 37 0.7 0.61 0.67 1.02 0.85 0.77 0.66 0.88 69 57 51 38.33333333 59 0.112537576 0.608620976 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0046872///metal ion binding GO:0006402///mRNA catabolic process+++GO:0050779///RNA destabilization+++GO:0061157///mRNA destabilization 237403 237403 'Lingo3' mRNA 165 146 82 2.61 2.27 1.36 0.3 0.15 0.23 2.08 0.226666667 22 11 16 131 16.33333333 5.26E-16 -3.006618539 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0008150///biological_process 237411 237411 'Zfp938' mRNA 365 381 415 9.91 10.21 11.88 6.53 6.95 6.58 10.66666667 6.686666667 279 292 272 387 281 0.001662523 -0.476130403 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 237412 237412 'Gm4924' mRNA 249 274 297 3.82 4.13 4.91 1.31 1.5 1.51 4.286666667 1.44 98 109 104 273.3333333 103.6666667 1.86E-13 -1.41311802 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 237422 237422 'Ric8b' mRNA 633 629 658 9.24 8.9 9.76 5.55 6.32 5.02 9.3 5.63 444 488 396 640 442.6666667 1.70E-05 -0.544770293 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex GO:0001965///G-protein alpha-subunit binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050790///regulation of catalytic activity 237433 237433 'Gm4925' mRNA 52 63 60 1.96 2.34 2.4 1.05 1.14 0.74 2.233333333 0.976666667 32 34 22 58.33333333 29.33333333 0.01116746 -1.004706476 03010///Ribosome+++05171///Coronavirus disease - COVID-19 237436 237436 'Gas2l3' mRNA 870.05 779.81 839.29 6.82 5.99 7.03 12.6 10.17 12.14 6.613333333 11.63666667 1850.42 1439.89 1718.47 829.7166667 1669.593333 3.77E-23 0.993703783 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0003779///actin binding+++GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0009617///response to bacterium+++GO:0030036///actin cytoskeleton organization+++GO:0051764///actin crosslink formation 237459 237459 'Cdk17' mRNA 348 289 266.11 4.95 3.94 4.02 4.32 3.77 4.32 4.303333333 4.136666667 343 291 330 301.0366667 321.3333333 0.679218748 0.083968537 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle 237465 237465 'Ccdc38' mRNA 9.04 12.05 11.06 0.14 0.18 0.18 0.26 0.19 0.11 0.166666667 0.186666667 19.1 14.04 8.05 10.71666667 13.73 0.722832259 0.341162369 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 237500 237500 'Tmtc3' mRNA 662 574 618 5.71 4.89 5.87 4.68 4.89 4.84 5.49 4.803333333 616.43 607.02 620 618 614.4833333 0.883686608 -0.021410283 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity GO:0006486///protein glycosylation+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035269///protein O-linked mannosylation+++GO:0048286///lung alveolus development+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0060447///bud outgrowth involved in lung branching+++GO:1901800///positive regulation of proteasomal protein catabolic process 237504 237504 'Rassf9' mRNA 512 532 534 7.6 8.06 8.83 2.76 2.53 2.84 8.163333333 2.71 208 151 189 526 182.6666667 1.14E-25 -1.540827907 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0012510///trans-Golgi network transport vesicle membrane+++GO:0055037///recycling endosome GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding GO:0007165///signal transduction+++GO:0016197///endosomal transport+++GO:0046907///intracellular transport 237523 237523 'Ptprq' mRNA 11423 11562 10627 63.25 62.36 62.23 5.39 4.28 5.02 62.61333333 4.896666667 1145 883 1031 11204 1019.666667 0 -3.470425734 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032421///stereocilium bundle+++GO:0043235///receptor complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0045598///regulation of fat cell differentiation+++GO:0050885///neuromuscular process controlling balance+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060116///vestibular receptor cell morphogenesis+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 237542 237542 'Osbpl8' mRNA 667.48 703.77 506.73 4.93 5.11 3.97 8.57 8.43 8.82 4.67 8.606666667 1332.81 1281.35 1330.14 625.9933333 1314.766667 4.65E-26 1.065384054 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0032541///cortical endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding GO:0006869///lipid transport+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0015914///phospholipid transport+++GO:0015918///sterol transport+++GO:0030336///negative regulation of cell migration+++GO:0032148///activation of protein kinase B activity+++GO:0045444///fat cell differentiation+++GO:0046326///positive regulation of glucose import+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0090204///protein localization to nuclear pore+++GO:0120009///intermembrane lipid transfer 237553 237553 'Trhde' mRNA 51 46 42 0.41 0.36 0.35 0.04 0.01 0.06 0.373333333 0.036666667 6 2 8 46.33333333 5.333333333 9.18E-08 -3.130905887 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0043171///peptide catabolic process 237558 237558 'Myrfl' mRNA 17 11 7 0.3 0.19 0.13 0.08 0.05 0.08 0.206666667 0.07 5 3 5 11.66666667 4.333333333 0.145309577 -1.432053957 GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0016540///protein autoprocessing+++GO:0045893///positive regulation of transcription, DNA-templated" 237560 237560 'Lrrc10' mRNA 2 0 0 0.08 0 0 0 0 0 0.026666667 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0030016///myofibril+++GO:0030017///sarcomere GO:0003779///actin binding+++GO:0051393///alpha-actinin binding GO:0055013///cardiac muscle cell development 237611 237611 'Stac3' mRNA 15 14 9 0.56 0.48 0.36 0.32 0.36 0.47 0.466666667 0.383333333 10 12 14 12.66666667 12 0.931060177 -0.079988552 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042383///sarcolemma+++GO:0045202///synapse GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0003009///skeletal muscle contraction+++GO:0007274///neuromuscular synaptic transmission+++GO:0035556///intracellular signal transduction+++GO:0048741///skeletal muscle fiber development+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1903078///positive regulation of protein localization to plasma membrane 237615 237615 'Ankrd52' mRNA 626 560 421 5.01 4.4 3.57 5.61 4.31 5.85 4.326666667 5.256666667 808 607 816 535.6666667 743.6666667 0.001388156 0.46593678 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 237625 237625 'Pla2g3' mRNA 403 401 397 8.7 8.53 9.02 0.76 1.1 0.89 8.75 0.916666667 41 54 47 400.3333333 47.33333333 2.27E-56 -3.091452288 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0055037///recycling endosome "GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0001675///acrosome assembly+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0007288///sperm axoneme assembly+++GO:0010629///negative regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010976///positive regulation of neuron projection development+++GO:0019372///lipoxygenase pathway+++GO:0030030///cell projection organization+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0042116///macrophage activation+++GO:0043303///mast cell degranulation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046337///phosphatidylethanolamine metabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048468///cell development+++GO:0048469///cell maturation+++GO:0050482///arachidonic acid secretion+++GO:0060271///cilium assembly+++GO:0060376///positive regulation of mast cell differentiation+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:1903595///positive regulation of histamine secretion by mast cell+++GO:2001135///regulation of endocytic recycling 237636 237636 'Npc1l1' mRNA 18 9 15 0.21 0.1 0.19 0.03 0.08 0.05 0.166666667 0.053333333 3 8 5 14 5.333333333 0.119131222 -1.40314615 04975///Fat digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0044214///spanning component of plasma membrane GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0031489///myosin V binding+++GO:1901363///heterocyclic compound binding GO:0006629///lipid metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006869///lipid transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0014850///response to muscle activity+++GO:0030299///intestinal cholesterol absorption+++GO:0030301///cholesterol transport+++GO:0042157///lipoprotein metabolic process+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0071501///cellular response to sterol depletion 237711 237711 'Eml6' mRNA 138.93 119.71 83.57 0.9 0.77 0.57 0.48 0.43 0.57 0.746666667 0.493333333 85.53 75.22 98.45 114.07 86.4 0.174998119 -0.402687389 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0008017///microtubule binding GO:0008150///biological_process 237716 237716 'Gpr75' mRNA 91.71 87.42 88 1.33 1.07 1.53 0.84 0.91 0.63 1.31 0.793333333 69 65.06 48.86 89.04333333 60.97333333 0.07185139 -0.560728637 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016493///C-C chemokine receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0070098///chemokine-mediated signaling pathway+++GO:1901214///regulation of neuron death 237754 237754 'Btnl9' mRNA 3 0 0 0.07 0 0 0.02 0.04 0.08 0.023333333 0.046666667 1 2 4 1 2.333333333 0.643208249 1.236196121 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 237758 237758 'Zfp454' mRNA 104 93 78 3 2.54 2.3 1.54 1.41 1.84 2.613333333 1.596666667 65 57 74 91.66666667 65.33333333 0.104039282 -0.497005285 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 237759 237759 'Col23a1' mRNA 150 130 126 1.41 1.2 1.25 0.77 0.58 0.91 1.286666667 0.753333333 94 69 108 135.3333333 90.33333333 0.022626413 -0.595233847 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0042802///identical protein binding GO:0030198///extracellular matrix organization 237761 237761 'Sowaha' mRNA 443 454 456 6.65 6.7 7.26 3.79 4 3.71 6.87 3.833333333 291 300 276 451 289 1.25E-06 -0.654596254 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 237775 237775 'Zfp867' mRNA 480.95 476.88 505.43 8.42 8.22 9.16 6.64 6.28 5.78 8.6 6.233333333 442.71 409.54 363.98 487.7533333 405.41 0.044514295 -0.281754509 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 237781 237781 'Mief2' mRNA 312 321 295 6.89 6.98 6.91 7.08 6.76 6.8 6.926666667 6.88 369 344 343 309.3333333 352 0.26450065 0.175077877 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0007005///mitochondrion organization+++GO:0010821///regulation of mitochondrion organization+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090314///positive regulation of protein targeting to membrane 237782 237782 'Smcr8' mRNA 283.75 252 231.88 2.34 1.95 1.79 3.26 2.47 3.22 2.026666667 2.983333333 483.38 370 455.3 255.8766667 436.2266667 3.72E-07 0.760279907 04140///Autophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:1990316///Atg1/ULK1 kinase complex GO:0004860///protein kinase inhibitor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0006469///negative regulation of protein kinase activity+++GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0010629///negative regulation of gene expression+++GO:0016242///negative regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:1901098///positive regulation of autophagosome maturation+++GO:1902902///negative regulation of autophagosome assembly+++GO:1903432///regulation of TORC1 signaling 237806 237806 'Dnah9' mRNA 672 719 639 3.25 3.27 3.17 0.36 0.34 0.27 3.23 0.323333333 91 80 53 676.6666667 74.66666667 7.71E-83 -3.191569318 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036157///outer dynein arm+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium+++GO:0120135///distal portion of axoneme "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0043015///gamma-tubulin binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0090660///cerebrospinal fluid circulation 237823 237823 'Pfas' mRNA 1213.29 1236.02 1444.46 10.09 10.1 12.74 6.96 6.89 7.79 10.97666667 7.213333333 963.89 931.81 1045.24 1297.923333 980.3133333 1.57E-04 -0.422243086 00230///Purine metabolism GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004642///phosphoribosylformylglycinamidine synthase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0042493///response to drug+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0097065///anterior head development+++GO:0097294///'de novo' XMP biosynthetic process 237831 237831 'Slc13a5' mRNA 67 78 59 1.19 1.3 1.06 2.4 1.97 2.61 1.183333333 2.326666667 160 123 163 68 148.6666667 7.24E-06 1.11870448 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005343///organic acid:sodium symporter activity+++GO:0015137///citrate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015142///tricarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0017153///sodium:dicarboxylate symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006842///tricarboxylic acid transport+++GO:0015729///oxaloacetate transport+++GO:0015741///fumarate transport+++GO:0015742///alpha-ketoglutarate transport+++GO:0015744///succinate transport+++GO:0015746///citrate transport+++GO:0035674///tricarboxylic acid transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071285///cellular response to lithium ion+++GO:0071422///succinate transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1903825///organic acid transmembrane transport 237847 237847 'Rtn4rl1' mRNA 265 207 220 4.41 3.38 3.85 1.52 1.46 1.55 3.88 1.51 106 96 104 230.6666667 102 3.20E-09 -1.189472335 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0008201///heparin binding+++GO:0035374///chondroitin sulfate binding+++GO:0038023///signaling receptor activity+++GO:0048495///Roundabout binding GO:0007411///axon guidance+++GO:0010977///negative regulation of neuron projection development+++GO:0022038///corpus callosum development+++GO:0048681///negative regulation of axon regeneration+++GO:0050919///negative chemotaxis 237858 237858 'Trarg1' mRNA 74 75 72 1.25 1.25 1.29 0.43 0.54 0.29 1.263333333 0.42 29 36 19 73.66666667 28 1.46E-04 -1.406369417 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0032869///cellular response to insulin stimulus+++GO:0044381///glucose import in response to insulin stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0099500///vesicle fusion to plasma membrane+++GO:0099638///endosome to plasma membrane protein transport 237859 237859 'Nsrp1' mRNA 675.48 685 769 11.88 11.85 14.34 10.38 11.05 11.9 12.69 11.11 679 706.36 754.01 709.8266667 713.1233333 0.96271297 -0.00795452 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0032502///developmental process" 237860 237860 'Ssh2' mRNA 725 728.12 605 3.33 3.09 2.97 7.84 7.45 7.53 3.13 7.606666667 1742 1556.89 1583.02 686.04 1627.303333 5.56E-47 1.236269346 04360///Axon guidance+++04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0003779///actin binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030335///positive regulation of cell migration+++GO:0030837///negative regulation of actin filament polymerization+++GO:0035335///peptidyl-tyrosine dephosphorylation 237868 237868 'Sarm1' mRNA 140 112 146 1.48 1.16 1.63 0.41 0.36 0.47 1.423333333 0.413333333 45 38 50 132.6666667 44.33333333 1.35E-08 -1.598568445 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031315///extrinsic component of mitochondrial outer membrane+++GO:0042995///cell projection+++GO:0045202///synapse "GO:0003953///NAD+ nucleosidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0035591///signaling adaptor activity+++GO:0042802///identical protein binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0009749///response to glucose+++GO:0019677///NAD catabolic process+++GO:0030154///cell differentiation+++GO:0034128///negative regulation of MyD88-independent toll-like receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0048678///response to axon injury+++GO:0048814///regulation of dendrite morphogenesis+++GO:1901214///regulation of neuron death+++GO:1901216///positive regulation of neuron death 237877 237877 'Atad5' mRNA 147 144 127 1.19 1.25 1.08 1.16 1.24 1.21 1.173333333 1.203333333 167 158 170 139.3333333 165 0.305916025 0.233999603 GO:0005634///nucleus+++GO:0031391///Elg1 RFC-like complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0061860///DNA clamp unloader activity GO:0002377///immunoglobulin production+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0030890///positive regulation of B cell proliferation+++GO:0033260///nuclear DNA replication+++GO:0042770///signal transduction in response to DNA damage+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0045190///isotype switching+++GO:0045740///positive regulation of DNA replication+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090618///DNA clamp unloading+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1902751///positive regulation of cell cycle G2/M phase transition 237886 237886 'Slfn9' mRNA 232.82 205.73 226.12 1.48 1.5 1.73 4.8 5.83 5.37 1.57 5.333333333 648.82 716.61 703.82 221.5566667 689.75 8.35E-36 1.62852938 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0090734///site of DNA damage GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0016075///rRNA catabolic process+++GO:0016078///tRNA catabolic process+++GO:0051607///defense response to virus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 23789 23789 'Coro1b' mRNA 2246 2325 2144 69.02 70.4 69.89 109.51 112.46 108.2 69.77 110.0566667 4102 4100 3914 2238.333333 4038.666667 4.96E-44 0.840546971 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0071933///Arp2/3 complex binding GO:0007015///actin filament organization+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0031529///ruffle organization+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0035767///endothelial cell chemotaxis+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042060///wound healing+++GO:0051017///actin filament bundle assembly+++GO:0070528///protein kinase C signaling+++GO:0071672///negative regulation of smooth muscle cell chemotaxis+++GO:0090135///actin filament branching+++GO:1902463///protein localization to cell leading edge+++GO:2000393///negative regulation of lamellipodium morphogenesis+++GO:2000394///positive regulation of lamellipodium morphogenesis 237890 237890 'Slfn14' mRNA 3 0 2 0.04 0 0.03 0 0.02 0 0.023333333 0.006666667 0 1 0 1.666666667 0.333333333 0.494453423 -2.242820423 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0043022///ribosome binding "GO:0006402///mRNA catabolic process+++GO:0016075///rRNA catabolic process+++GO:0036345///platelet maturation+++GO:0071286///cellular response to magnesium ion+++GO:0071287///cellular response to manganese ion+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 237891 237891 'Gas2l2' mRNA 324 287 262 6.06 5.28 5.19 0.41 0.47 0.55 5.51 0.476666667 25 28 33 291 28.66666667 7.99E-45 -3.35248286 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0035371///microtubule plus-end+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0051764///actin crosslink formation+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:1904825///protein localization to microtubule plus-end 237898 237898 'Usp32' mRNA 532 617 485 4.06 4.63 3.93 3.82 3.35 3.42 4.206666667 3.53 576 494 500 544.6666667 523.3333333 0.673852203 -0.067317146 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0055037///recycling endosome GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 23790 23790 'Coro1c' mRNA 802 786 804 12.71 12.25 13.51 44.28 40.41 42.23 12.82333333 42.30666667 3216 2867 2970 797.3333333 3017.666667 2.41E-141 1.906680378 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0031982///vesicle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0031267///small GTPase binding+++GO:0051015///actin filament binding GO:0000147///actin cortical patch assembly+++GO:0001755///neural crest cell migration+++GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006909///phagocytosis+++GO:0007015///actin filament organization+++GO:0010632///regulation of epithelial cell migration+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010762///regulation of fibroblast migration+++GO:0016197///endosomal transport+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045184///establishment of protein localization+++GO:0051893///regulation of focal adhesion assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0090148///membrane fission+++GO:0090630///activation of GTPase activity+++GO:0097750///endosome membrane tubulation+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1900027///regulation of ruffle assembly+++GO:2000394///positive regulation of lamellipodium morphogenesis 237911 237911 'Brip1' mRNA 1252.31 1310.25 1242.46 9.55 9.82 10.05 3.45 2.88 3.25 9.806666667 3.193333333 520.21 425.26 474.83 1268.34 473.4333333 1.25E-49 -1.435732746 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane "GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0043139///5'-3' DNA helicase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000117///regulation of transcription involved in G2/M transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0007284///spermatogonial cell division+++GO:0007286///spermatid development+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009636///response to toxic substance+++GO:0010629///negative regulation of gene expression+++GO:0010705///meiotic DNA double-strand break processing involved in reciprocal meiotic recombination+++GO:0032508///DNA duplex unwinding+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051026///chiasma assembly+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0071295///cellular response to vitamin+++GO:0071456///cellular response to hypoxia+++GO:0072520///seminiferous tubule development+++GO:1904385///cellular response to angiotensin+++GO:1990918///double-strand break repair involved in meiotic recombination" 23792 23792 'Adam23' mRNA 87 83 46 0.74 0.68 0.41 0.2 0.34 0.22 0.61 0.253333333 28 45 29 72 34 0.006050944 -1.079405639 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:1990830///cellular response to leukemia inhibitory factor 237926 237926 'Rsad1' mRNA 189 252 212 2.4 3.15 2.84 1.73 1.81 1.94 2.796666667 1.826666667 156 160 169 217.6666667 161.6666667 0.028578901 -0.439424038 GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0003824///catalytic activity+++GO:0004109///coproporphyrinogen oxidase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006779///porphyrin-containing compound biosynthetic process 237928 237928 'Phospho1' mRNA 7.88 18.64 7.81 0.24 0.55 0.25 0.17 0.17 0.17 0.346666667 0.17 6.37 6.28 6.15 11.44333333 6.266666667 0.421945962 -0.828337712 00564///Glycerophospholipid metabolism GO:0031012///extracellular matrix+++GO:0065010///extracellular membrane-bounded organelle GO:0016462///pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0052731///phosphocholine phosphatase activity+++GO:0052732///phosphoethanolamine phosphatase activity GO:0001958///endochondral ossification+++GO:0016311///dephosphorylation+++GO:0030500///regulation of bone mineralization+++GO:0035630///bone mineralization involved in bone maturation 237930 237930 'Ttll6' mRNA 141 154 128 1.81 1.79 1.64 1.39 1.05 1.32 1.746666667 1.253333333 123 96 124 141 114.3333333 0.21027512 -0.31309258 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097731///9+0 non-motile cilium GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070739///protein-glutamic acid ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0003353///positive regulation of cilium movement+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation+++GO:0051013///microtubule severing 237934 237934 'Krt39' mRNA 4 1 0 0.07 0.02 0 0 0 0 0.03 0 0 0 0 1.666666667 0 0.388125747 -3.161307148 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 23794 23794 'Adamts5' mRNA 489 555 551 3.24 3.54 3.79 1.54 1.61 1.91 3.523333333 1.686666667 270 244 315 531.6666667 276.3333333 2.05E-11 -0.957783041 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding GO:0006508///proteolysis+++GO:0007520///myoblast fusion+++GO:0022617///extracellular matrix disassembly+++GO:0030198///extracellular matrix organization+++GO:0042742///defense response to bacterium+++GO:0044691///tooth eruption+++GO:0120163///negative regulation of cold-induced thermogenesis 237940 237940 'Aoc2' mRNA 55.92 48.11 40.67 1.11 0.93 0.83 0.9 0.84 0.64 0.956666667 0.793333333 50.57 45.01 39.01 48.23333333 44.86333333 0.845973442 -0.102686254 "00260///Glycine, serine and threonine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism" GO:0005886///plasma membrane GO:0005507///copper ion binding+++GO:0008131///primary amine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0048038///quinone binding+++GO:0052593///tryptamine:oxygen oxidoreductase (deaminating) activity+++GO:0052594///aminoacetone:oxygen oxidoreductase(deaminating) activity+++GO:0052595///aliphatic-amine oxidase activity+++GO:0052596///phenethylamine:oxygen oxidoreductase (deaminating) activity GO:0006584///catecholamine metabolic process+++GO:0007601///visual perception+++GO:0009308///amine metabolic process 237943 237943 'Gpatch8' mRNA 2526.73 2442.12 2116.41 13.92 13.49 13.25 11.46 10.08 10.12 13.55333333 10.55333333 2257.02 1876.27 1940.83 2361.753333 2024.706667 0.004812281 -0.232787215 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process 23795 23795 'Agr2' mRNA 27 20 22 2.46 1.81 2.13 0.96 1.8 0.91 2.133333333 1.223333333 12 22 11 23 15 0.354668686 -0.624355166 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum GO:0002162///dystroglycan binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0042802///identical protein binding GO:0010628///positive regulation of gene expression+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0048546///digestive tract morphogenesis+++GO:0048639///positive regulation of developmental growth+++GO:0060480///lung goblet cell differentiation+++GO:0060548///negative regulation of cell death+++GO:0070254///mucus secretion+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:1903899///positive regulation of PERK-mediated unfolded protein response 23796 23796 'Aplnr' mRNA 56 67 49 0.85 1 0.79 2.79 2.09 2.6 0.88 2.493333333 211 154 190 57.33333333 185 2.65E-12 1.679729743 04080///Neuroactive ligand-receptor interaction+++04371///Apelin signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0060182///apelin receptor activity GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001944///vasculature development+++GO:0001947///heart looping+++GO:0003171///atrioventricular valve development+++GO:0003272///endocardial cushion formation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0007507///heart development+++GO:0007512///adult heart development+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0031065///positive regulation of histone deacetylation+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0035904///aorta development+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045766///positive regulation of angiogenesis+++GO:0050878///regulation of body fluid levels+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060183///apelin receptor signaling pathway+++GO:0060412///ventricular septum morphogenesis+++GO:0060841///venous blood vessel development+++GO:0060976///coronary vasculature development+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1903596///regulation of gap junction assembly+++GO:1904325///positive regulation of inhibitory G protein-coupled receptor phosphorylation 23797 23797 'Akt3' mRNA 655.87 658.74 637.74 4.84 4.84 5.17 2.94 2.29 2.71 4.95 2.646666667 441.91 338.12 398.39 650.7833333 392.8066667 1.27E-09 -0.742072464 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000002///mitochondrial genome maintenance+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0010765///positive regulation of sodium ion transport+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032008///positive regulation of TOR signaling+++GO:0032869///cellular response to insulin stimulus+++GO:0035556///intracellular signal transduction+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0045793///positive regulation of cell size+++GO:0048854///brain morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1905653///positive regulation of artery morphogenesis+++GO:2000773///negative regulation of cellular senescence 237979 237979 'Sdk2' mRNA 138.15 132.57 104 0.67 0.64 0.54 0.55 0.6 0.57 0.616666667 0.573333333 128 137.97 132.51 124.9066667 132.8266667 0.795197175 0.079337214 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0010842///retina layer formation+++GO:0060219///camera-type eye photoreceptor cell differentiation 237987 237987 'Otop2' mRNA 0 1 0 0 0.02 0 0.11 0 0.04 0.006666667 0.05 5 0 2 0.333333333 2.333333333 0.358259765 2.672138403 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015252///proton channel activity GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 237988 237988 'Cdr2l' mRNA 230 262 260 3.34 3.74 4.03 4.75 3.61 3.83 3.703333333 4.063333333 375 278 294 250.6666667 315.6666667 0.077924721 0.31674668 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 23801 23801 'Aloxe3' mRNA 82 76 58 1.73 1.51 1.3 1.03 1.06 0.81 1.513333333 0.966666667 59 60 46 72 55 0.269517011 -0.395244185 GO:0005737///cytoplasm "GO:0003824///catalytic activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding+++GO:0050486///intramolecular transferase activity, transferring hydroxy groups+++GO:0051120///hepoxilin A3 synthase activity+++GO:0051213///dioxygenase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008544///epidermis development+++GO:0019233///sensory perception of pain+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0043651///linoleic acid metabolic process+++GO:0045444///fat cell differentiation+++GO:0046513///ceramide biosynthetic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0061436///establishment of skin barrier+++GO:0070830///bicellular tight junction assembly 23802 23802 'Amfr' mRNA 4620 4848 2604 70.12 72.07 42.84 31.57 37.64 40.38 61.67666667 36.53 2332 2732 2902 4024 2655.333333 0.029692178 -0.595876352 04141///Protein processing in endoplasmic reticulum GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030674///protein binding, bridging+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1904288///BAT3 complex binding+++GO:1990381///ubiquitin-specific protease binding" GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007568///aging+++GO:0007611///learning or memory+++GO:0009987///cellular process+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032092///positive regulation of protein binding+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000638///regulation of SREBP signaling pathway 238021 238021 'Fscn2' mRNA 2257 2304 2222 70.28 70.8 73.74 5.5 7.18 7.71 71.60666667 6.796666667 202 254 271 2261 242.3333333 6.99E-210 -3.232363569 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0032420///stereocilium+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0030674///protein binding, bridging+++GO:0051015///actin filament binding" GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0042462///eye photoreceptor cell development+++GO:0051017///actin filament bundle assembly 238023 238023 'Hexdc' mRNA 957.68 973.32 842.17 17.22 17.41 16.1 10.89 10.71 10.91 16.91 10.83666667 697.9 664.67 664.36 924.39 675.6433333 1.06E-06 -0.462791939 00511///Other glycan degradation+++00513///Various types of N-glycan biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1903561///extracellular vesicle "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0015929///hexosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process 238024 238024 'Fn3krp' mRNA 376 300 290 9.4 7.27 7.23 5.03 5.39 5.15 7.966666667 5.19 237 248 235 322 240 0.009413325 -0.433480197 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0102193///protein-ribulosamine 3-kinase activity GO:0016310///phosphorylation 238037 238037 'Wdcp' mRNA 719.62 614.78 729.9 9.2 7.64 9.5 9.88 8.85 8.19 8.78 8.973333333 933.16 836.55 748.72 688.1 839.4766667 0.035372069 0.271296796 GO:0005575///cellular_component GO:0019900///kinase binding GO:0051259///protein complex oligomerization 23805 23805 'Apc2' mRNA 725 766 661 4.13 4.29 3.97 2.7 2.64 2.26 4.13 2.533333333 546 521 443 717.3333333 503.3333333 6.06E-06 -0.521426931 04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04810///Regulation of actin cytoskeleton+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005884///actin filament+++GO:0015630///microtubule cytoskeleton+++GO:0016342///catenin complex+++GO:0030496///midbody+++GO:0030877///beta-catenin destruction complex+++GO:0031258///lamellipodium membrane+++GO:0031941///filamentous actin+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0008013///beta-catenin binding+++GO:0008017///microtubule binding+++GO:0045295///gamma-catenin binding GO:0000226///microtubule cytoskeleton organization+++GO:0001708///cell fate specification+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0045595///regulation of cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090630///activation of GTPase activity 238055 238055 'Apob' mRNA 0 3 2 0 0.01 0.01 0.02 0.03 0.01 0.006666667 0.02 7 8 4 1.666666667 6.333333333 0.197885332 1.913591184 04975///Fat digestion and absorption+++04977///Vitamin digestion and absorption+++04979///Cholesterol metabolism+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0012506///vesicle membrane+++GO:0031983///vesicle lumen+++GO:0034359///mature chylomicron+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034363///intermediate-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0042627///chylomicron+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0005319///lipid transporter activity+++GO:0005543///phospholipid binding+++GO:0008201///heparin binding+++GO:0035473///lipase binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0001701///in utero embryonic development+++GO:0006629///lipid metabolic process+++GO:0006642///triglyceride mobilization+++GO:0006869///lipid transport+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009566///fertilization+++GO:0009615///response to virus+++GO:0009743///response to carbohydrate+++GO:0009791///post-embryonic development+++GO:0010033///response to organic substance+++GO:0010269///response to selenium ion+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010884///positive regulation of lipid storage+++GO:0010886///positive regulation of cholesterol storage+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0030301///cholesterol transport+++GO:0030317///flagellated sperm motility+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0033344///cholesterol efflux+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034383///low-density lipoprotein particle clearance+++GO:0042157///lipoprotein metabolic process+++GO:0042158///lipoprotein biosynthetic process+++GO:0042159///lipoprotein catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0042953///lipoprotein transport+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0048844///artery morphogenesis+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071379///cellular response to prostaglandin stimulus+++GO:0120009///intermembrane lipid transfer 23806 23806 'Arih1' mRNA 480 473 456 2.65 2.58 2.48 3.43 2.78 3.09 2.57 3.1 706 583 653 469.6666667 647.3333333 1.14E-04 0.4499641 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0097413///Lewy body GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 23807 23807 'Arih2' mRNA 1580.58 1622.94 1707.86 20.66 20.95 23.84 17.72 15.29 16.59 21.81666667 16.53333333 1543.5 1292.47 1409.24 1637.126667 1415.07 0.017656619 -0.225554668 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031466///Cul5-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0048588///developmental cell growth+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0071425///hematopoietic stem cell proliferation 238076 238076 'Kcns3' mRNA 466 521 414 10.82 12.4 10.13 1.9 2.46 2.15 11.11666667 2.17 86 112 99 467 99 2.51E-41 -2.244576855 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 23808 23808 'Ash2l' mRNA 942.01 1086.3 258.03 18.24 20.8 4.72 5.9 9.73 10.24 14.58666667 8.623333333 394.76 570.04 603.01 762.1133333 522.6033333 0.482854192 -0.525585068 04934///Cushing syndrome GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex+++GO:0071339///MLL1 complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0043627///response to estrogen+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0051568///histone H3-K4 methylation" 238123 238123 'Cog5' mRNA 685.51 669.16 683.45 8.29 8.17 8.63 5.44 5.13 5.72 8.363333333 5.43 536.56 495.84 526 679.3733333 519.4666667 3.14E-04 -0.400856291 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0003674///molecular_function GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0048219///inter-Golgi cisterna vesicle-mediated transport 238130 238130 'Dock4' mRNA 414 427 390 2.62 2.68 2.64 1.95 1.71 2.05 2.646666667 1.903333333 358 312 370 410.3333333 346.6666667 0.077158891 -0.254694217 04015///Rap1 signaling pathway GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding+++GO:0030165///PDZ domain binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031267///small GTPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060326///cell chemotaxis+++GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration 238161 238161 'Akap6' mRNA 1238 1069.01 975.54 5.33 4.66 4.58 0.51 0.5 0.58 4.856666667 0.53 124.13 122.96 136.13 1094.183333 127.74 4.21E-127 -3.112065499 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005901///caveola+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0014704///intercalated disc+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0034704///calcium channel complex+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008179///adenylate cyclase binding+++GO:0016301///kinase activity+++GO:0019899///enzyme binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0043495///protein membrane anchor+++GO:0044325///ion channel binding+++GO:0051018///protein kinase A binding+++GO:0051721///protein phosphatase 2A binding+++GO:0060090///molecular adaptor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0010738///regulation of protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0031503///protein-containing complex localization+++GO:0034629///cellular protein-containing complex localization+++GO:0045727///positive regulation of translation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060306///regulation of membrane repolarization+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0071320///cellular response to cAMP+++GO:0071345///cellular response to cytokine stimulus+++GO:0071872///cellular response to epinephrine stimulus+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1901897///regulation of relaxation of cardiac muscle+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity 238205 238205 'Lrfn5' mRNA 105 113 86 1.22 1.32 1.06 0.75 0.65 0.82 1.2 0.74 74 64 77 101.3333333 71.66666667 0.075142935 -0.507827787 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0043031///negative regulation of macrophage activation+++GO:0050728///negative regulation of inflammatory response+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 23821 23821 'Bace1' mRNA 1889.77 1915.22 1758.35 23.02 23.02 22.71 10.99 9.54 11.78 22.91666667 10.77 1032.74 860.18 1081.43 1854.446667 991.45 2.93E-25 -0.915438831 05010///Alzheimer disease GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045121///membrane raft+++GO:0055037///recycling endosome+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse GO:0001540///amyloid-beta binding+++GO:0004175///endopeptidase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007613///memory+++GO:0009314///response to radiation+++GO:0010288///response to lead ion+++GO:0016485///protein processing+++GO:0034205///amyloid-beta formation+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048167///regulation of synaptic plasticity+++GO:0050435///amyloid-beta metabolic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain+++GO:0060134///prepulse inhibition+++GO:0071280///cellular response to copper ion+++GO:0071287///cellular response to manganese ion+++GO:1904646///cellular response to amyloid-beta+++GO:2000300///regulation of synaptic vesicle exocytosis 238217 238217 'Rpl10l' mRNA 1 0 2 0.06 0 0.13 0 0 0 0.063333333 0 0 0 0 1 0 0.59486514 -2.49405383 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0022625///cytosolic large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation+++GO:0007283///spermatogenesis 238247 238247 'Arid4a' mRNA 1004 985 972 9.29 8.95 9.55 8.48 8.37 8.87 9.263333333 8.573333333 1054 1020 1073 987 1049 0.480972652 0.075831379 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0017053///transcriptional repressor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding "GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0034773///histone H4-K20 trimethylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048821///erythrocyte development+++GO:0080182///histone H3-K4 trimethylation+++GO:0097368///establishment of Sertoli cell barrier" 23825 23825 'Banf1' mRNA 1602 1504 1551 127.03 118.39 131.82 166.07 167.1 163.88 125.7466667 165.6833333 2421 2386 2271 1552.333333 2359.333333 1.99E-15 0.591170339 GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0097726///LEM domain binding GO:0007059///chromosome segregation+++GO:0015074///DNA integration+++GO:0030261///chromosome condensation+++GO:0045071///negative regulation of viral genome replication+++GO:0075713///establishment of integrated proviral latency 238257 238257 'Tmem30b' mRNA 2995 3267 3224 49.82 53.48 56.89 23.83 23.7 23.86 53.39666667 23.79666667 1648 1601 1598 3162 1615.666667 2.01E-41 -0.981995526 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015247///aminophospholipid transmembrane transporter activity GO:0006869///lipid transport+++GO:0015917///aminophospholipid transport+++GO:0045332///phospholipid translocation+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum 238266 238266 'Syt16' mRNA 79 94 85 1.44 1.7 1.61 0.16 0.1 0.01 1.583333333 0.09 12 5 1 86 6 2.75E-14 -3.858213245 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0042802///identical protein binding GO:0006887///exocytosis 23827 23827 'Bpnt1' mRNA 1073.02 1149.42 1037.88 27.13 28.67 28.03 20.07 20.17 20.93 27.94333333 20.39 898.25 878.22 905.68 1086.773333 894.05 0.001103264 -0.292431345 00920///Sulfur metabolism "GO:0000287///magnesium ion binding+++GO:0004441///inositol-1,4-bisphosphate 1-phosphatase activity+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0046854///phosphatidylinositol phosphorylation+++GO:0046855///inositol phosphate dephosphorylation 238271 238271 'Kcnh5' mRNA 11 13 15 0.15 0.17 0.21 0.01 0.04 0.03 0.176666667 0.026666667 1 4 5 13 3.333333333 0.043806838 -1.974566588 GO:0005622///intracellular+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 238276 238276 'Akap5' mRNA 50 54 36 0.4 0.42 0.3 0.38 0.13 0.28 0.373333333 0.263333333 54.86 19 39 46.66666667 37.62 0.530795999 -0.333761119 "GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031527///filopodium membrane+++GO:0032279///asymmetric synapse+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0098837///postsynaptic recycling endosome+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0001664///G protein-coupled receptor binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008179///adenylate cyclase binding+++GO:0017124///SH3 domain binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030346///protein phosphatase 2B binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0035254///glutamate receptor binding+++GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0050811///GABA receptor binding+++GO:0060090///molecular adaptor activity+++GO:0097110///scaffold protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010738///regulation of protein kinase A signaling+++GO:0036394///amylase secretion+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043113///receptor clustering+++GO:0043267///negative regulation of potassium ion transport+++GO:0043271///negative regulation of ion transport+++GO:0043624///cellular protein complex disassembly+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0070073///clustering of voltage-gated calcium channels+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905751///positive regulation of endosome to plasma membrane protein transport 23828 23828 'Bves' mRNA 156 177 138 1.88 2.09 1.71 0.15 0.16 0.13 1.893333333 0.146666667 14 15 12 157 13.66666667 1.28E-26 -3.529957656 04530///Tight junction GO:0000172///ribonuclease MRP complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030681///multimeric ribonuclease P complex+++GO:0031253///cell projection membrane+++GO:0042383///sarcolemma GO:0000166///nucleotide binding+++GO:0004526///ribonuclease P activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0001921///positive regulation of receptor recycling+++GO:0002027///regulation of heart rate+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002931///response to ischemia+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0008033///tRNA processing+++GO:0008360///regulation of cell shape+++GO:0016078///tRNA catabolic process+++GO:0016192///vesicle-mediated transport+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0040017///positive regulation of locomotion+++GO:0042391///regulation of membrane potential+++GO:0043087///regulation of GTPase activity+++GO:0048278///vesicle docking+++GO:0051146///striated muscle cell differentiation+++GO:0060931///sinoatrial node cell development+++GO:0060973///cell migration involved in heart development+++GO:0090136///epithelial cell-cell adhesion+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:2001135///regulation of endocytic recycling" 23829 23829 'C1ql1' mRNA 17 15 4 0.67 0.58 0.17 0.31 0.28 0.25 0.473333333 0.28 9 8 7 12 8 0.572080699 -0.577333463 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0043083///synaptic cleft+++GO:0044301///climbing fiber+++GO:0098793///presynapse GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0016322///neuron remodeling+++GO:0061743///motor learning+++GO:0099558///maintenance of synapse structure 23830 23830 'Capn10' mRNA 840 856 811 16.09 16.13 16.47 7.61 8.88 7.2 16.23 7.896666667 457 521 419 835.6666667 465.6666667 6.03E-14 -0.854202753 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0043231///intracellular membrane-bounded organelle GO:0000149///SNARE binding+++GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000422///autophagy of mitochondrion+++GO:0006508///proteolysis+++GO:0007005///mitochondrion organization+++GO:0007568///aging+++GO:0007586///digestion+++GO:0031532///actin cytoskeleton reorganization+++GO:0031667///response to nutrient levels+++GO:0032024///positive regulation of insulin secretion+++GO:0032388///positive regulation of intracellular transport+++GO:0032869///cellular response to insulin stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0046326///positive regulation of glucose import+++GO:0097050///type B pancreatic cell apoptotic process+++GO:1990092///calcium-dependent self proteolysis+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process 23831 23831 'Car14' mRNA 5272.62 5606.41 5064.22 196.94 204.65 197.82 144.68 149.52 141.23 199.8033333 145.1433333 4429.73 4503.41 4211.63 5314.416667 4381.59 1.18E-06 -0.289077314 00910///Nitrogen metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0006885///regulation of pH+++GO:0015670///carbon dioxide transport 238317 238317 'Mideas' mRNA 1296.36 1268.38 951.15 9.94 9.62 7.74 8.12 7.37 8.43 9.1 7.973333333 1221.2 1072.8 1233.85 1171.963333 1175.95 0.994543387 -0.002218826 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex GO:0003714///transcription corepressor activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated" 23832 23832 'Xcr1' mRNA 8.02 12.37 8.74 0.1 0.15 0.11 0.48 0.31 0.28 0.12 0.356666667 46.02 28.87 25.69 9.71 33.52666667 0.002189215 1.809098241 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0034097///response to cytokine+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 238323 238323 'Rps6kl1' mRNA 154 164 160 3.11 3.35 3.46 0.54 0.47 0.72 3.306666667 0.576666667 32 27 41 159.3333333 33.33333333 8.37E-17 -2.269831398 GO:0005840///ribosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 238328 238328 'Vash1' mRNA 104.35 116.09 69.14 0.87 0.91 0.6 1.55 1.37 1.75 0.793333333 1.556666667 219.51 187.32 239.68 96.52666667 215.5033333 2.17E-07 1.153748063 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0045177///apical part of cell GO:0003779///actin binding+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0001525///angiogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006508///proteolysis+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0009611///response to wounding+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0016525///negative regulation of angiogenesis+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045765///regulation of angiogenesis+++GO:0051726///regulation of cell cycle+++GO:0060674///placenta blood vessel development+++GO:0060716///labyrinthine layer blood vessel development+++GO:1901491///negative regulation of lymphangiogenesis+++GO:2000772///regulation of cellular senescence 23833 23833 'Cd52' mRNA 89 81 85 14.94 13.6 15.15 178.6 209.19 198.54 14.56333333 195.4433333 1210 1375 1294 85 1293 3.28E-182 3.916904781 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0097225///sperm midpiece GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009617///response to bacterium 238330 238330 'Irf2bpl' mRNA 2010 2015 1754 26.35 25.98 24.39 25.27 22.13 24.62 25.57333333 24.00666667 2219 1898 2094 1926.333333 2070.333333 0.280721359 0.09340506 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003714///transcription corepressor activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0016567///protein ubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046543///development of secondary female sexual characteristics 238331 238331 'Zdhhc22' mRNA 21 32 34 0.31 0.44 0.54 0.21 0.18 0.12 0.43 0.17 15.18 13 9 29 12.39333333 0.03432986 -1.252202359 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0072659///protein localization to plasma membrane 238333 238333 'Samd15' mRNA 42 49 47 1.16 1.33 1.37 0.29 0.15 0.32 1.286666667 0.253333333 12 6 13 46 10.33333333 1.94E-05 -2.169728363 GO:0003674///molecular_function 23834 23834 'Cdc6' mRNA 50 48 35 0.58 0.55 0.43 1.89 2.33 2.02 0.52 2.08 187 226 194 44.33333333 202.3333333 3.01E-19 2.184688884 04110///Cell cycle+++05207///Chemical carcinogenesis - receptor activation GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0019900///kinase binding GO:0000278///mitotic cell cycle+++GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0007049///cell cycle+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0032467///positive regulation of cytokinesis+++GO:0033314///mitotic DNA replication checkpoint+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051301///cell division+++GO:0051984///positive regulation of chromosome segregation+++GO:1904117///cellular response to vasopressin+++GO:1904385///cellular response to angiotensin 23836 23836 'Cdh20' mRNA 26 24 16 0.35 0.32 0.23 0.23 0.3 0.25 0.3 0.26 20 25 21 22 22 0.998591786 -0.002628475 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 23837 23837 'Cfdp1' mRNA 1976 1992 1940 35.76 35.48 37.25 31.22 30.71 31.16 36.16333333 31.03 1985 1906 1918 1969.333333 1936.333333 0.698542562 -0.036612375 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005604///basement membrane+++GO:0005694///chromosome" GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0008360///regulation of cell shape+++GO:0042127///regulation of cell proliferation+++GO:2000270///negative regulation of fibroblast apoptotic process 238377 238377 'Gpr68' mRNA 24.95 36.9 26.21 0.43 0.65 0.48 0.82 1.28 1.04 0.52 1.046666667 55.44 82.12 66.45 29.35333333 68.00333333 0.001344273 1.23387784 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032024///positive regulation of insulin secretion+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045656///negative regulation of monocyte differentiation+++GO:0071467///cellular response to pH+++GO:2001206///positive regulation of osteoclast development 238384 238384 'Slc24a4' mRNA 3 1 1 0.05 0.02 0.02 0 0 0 0.03 0 0 0 0 1.666666667 0 0.334169217 -3.181769893 04740///Olfactory transduction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031982///vesicle "GO:0005262///calcium channel activity+++GO:0005432///calcium:sodium antiporter activity+++GO:0005516///calmodulin binding+++GO:0008273///calcium, potassium:sodium antiporter activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity+++GO:0048306///calcium-dependent protein binding" GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007602///phototransduction+++GO:0007608///sensory perception of smell+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0010628///positive regulation of gene expression+++GO:0021630///olfactory nerve maturation+++GO:0035725///sodium ion transmembrane transport+++GO:0036368///cone photoresponse recovery+++GO:0042756///drinking behavior+++GO:0050849///negative regulation of calcium-mediated signaling+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0055074///calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071486///cellular response to high light intensity+++GO:0071805///potassium ion transmembrane transport+++GO:0086009///membrane repolarization+++GO:0097186///amelogenesis+++GO:0098656///anion transmembrane transport+++GO:0098703///calcium ion import across plasma membrane+++GO:1903998///regulation of eating behavior+++GO:1990034///calcium ion export across plasma membrane+++GO:1990680///response to melanocyte-stimulating hormone+++GO:1990834///response to odorant 238386 238386 'Btbd7' mRNA 769 734 717 5.02 4.82 5.01 3.83 3.32 4.08 4.95 3.743333333 670 560 698 740 642.6666667 0.07293748 -0.216073379 GO:0005634///nucleus GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0061138///morphogenesis of a branching epithelium 238393 238393 'Serpina3f' mRNA 30.66 27.26 36.38 0.85 0.75 1.04 2.09 2.25 2.39 0.88 2.243333333 87.09 94.29 97.74 31.43333333 93.04 1.70E-06 1.564577858 GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0009617///response to bacterium+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 23845 23845 'Clec5a' mRNA 37 34 32 0.53 0.48 0.49 12.24 11.8 12.71 0.5 12.25 984 925 989 34.33333333 966 9.76E-161 4.803479593 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0001819///positive regulation of cytokine production+++GO:0002076///osteoblast development+++GO:0002376///immune system process+++GO:0030099///myeloid cell differentiation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0046718///viral entry into host cell 238455 238455 'Macc1' mRNA 92 99 80 1.22 1.28 1.09 2.49 2.04 2.57 1.196666667 2.366666667 223 178 223 90.33333333 208 1.31E-08 1.192956435 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0045944///positive regulation of transcription by RNA polymerase II 23849 23849 'Klf6' mRNA 1287 1172 1358 16.43 14.72 18.39 37.14 35.68 39.16 16.51333333 37.32666667 3349 3143 3420 1272.333333 3304 8.23E-59 1.361286006 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1905205///positive regulation of connective tissue replacement 23850 23850 'Pappa2' mRNA 1 0 1 0.01 0 0.01 0.01 0.02 0.02 0.006666667 0.016666667 1 4 5 0.666666667 3.333333333 0.289630323 2.306907001 GO:0005829///cytosol+++GO:0016324///apical plasma membrane GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding GO:0006508///proteolysis+++GO:0009651///response to salt stress+++GO:0060349///bone morphogenesis 238505 238505 'Mtr' mRNA 481 434 382 3.39 3.14 3.2 3.91 3.43 3.52 3.243333333 3.62 537 449 456 432.3333333 480.6666667 0.347739005 0.142390761 00270///Cysteine and methionine metabolism+++00450///Selenocompound metabolism+++00670///One carbon pool by folate+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005542///folic acid binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008705///methionine synthase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0031419///cobalamin binding+++GO:0046872///metal ion binding GO:0006479///protein methylation+++GO:0006555///methionine metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0009235///cobalamin metabolic process+++GO:0031103///axon regeneration+++GO:0032259///methylation+++GO:0042558///pteridine-containing compound metabolic process+++GO:0044237///cellular metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0048678///response to axon injury+++GO:0050667///homocysteine metabolic process+++GO:0071732///cellular response to nitric oxide 23853 23853 'Def6' mRNA 184 235 224 4.54 5.71 5.86 8.56 8.09 8.22 5.37 8.29 399 368 371 214.3333333 379.3333333 2.40E-07 0.810008866 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030175///filopodium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding 23854 23854 'Def8' mRNA 1229.14 1341.01 1240.9 18.67 18.96 20 15.9 16.48 14.46 19.21 15.61333333 1183.01 1264 1073.03 1270.35 1173.346667 0.235479453 -0.125212158 GO:0005575///cellular_component GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0032418///lysosome localization+++GO:0035556///intracellular signal transduction+++GO:0045780///positive regulation of bone resorption+++GO:1900029///positive regulation of ruffle assembly 238555 238555 'Btn2a2' mRNA 258 268 292 5.14 6.16 6.5 0.64 0.29 0.57 5.933333333 0.5 33 17 32 272.6666667 27.33333333 1.20E-38 -3.335709426 GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0001818///negative regulation of cytokine production+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0031324///negative regulation of cellular metabolic process+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 23856 23856 'Dido1' mRNA 2358.5 2322.48 2230.31 15.54 15.48 16.09 12.63 11.27 12.5 15.70333333 12.13333333 2026.42 1839.57 2017.23 2303.763333 1961.073333 6.59E-04 -0.244472817 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway" 238564 238564 'Mylk4' mRNA 140.39 112.28 133.97 1.13 0.89 1.14 0.21 0.14 0.12 1.053333333 0.156666667 30 19.94 16 128.88 21.98 3.57E-15 -2.583995422 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04971///Gastric acid secretion GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004687///myosin light chain kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 23857 23857 'Dmtf1' mRNA 1096.7 1131.25 1083.66 15.53 15.87 16.37 12.78 10.74 11.11 15.92333333 11.54333333 1005.08 824.72 857.18 1103.87 895.66 0.001338947 -0.314870216 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031012///extracellular matrix "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0030544///Hsp70 protein binding+++GO:0050840///extracellular matrix binding" "GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0031214///biomineral tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070173///regulation of enamel mineralization" 23859 23859 'Dlg2' mRNA 967.06 1014.04 798 5.23 5.85 4.57 0.39 0.4 0.51 5.216666667 0.433333333 80.07 93 111 926.3666667 94.69 1.81E-113 -3.297070205 04390///Hippo signaling pathway+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043204///perikaryon+++GO:0044224///juxtaparanode region of axon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099031///anchored component of postsynaptic density membrane+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019900///kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030165///PDZ domain binding+++GO:0044877///protein-containing complex binding+++GO:0098919///structural constituent of postsynaptic density GO:0007268///chemical synaptic transmission+++GO:0009790///embryo development+++GO:0010923///negative regulation of phosphatase activity+++GO:0019233///sensory perception of pain+++GO:0035865///cellular response to potassium ion+++GO:0043113///receptor clustering+++GO:0045161///neuronal ion channel clustering+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0099641///anterograde axonal protein transport+++GO:0099642///retrograde axonal protein transport+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 23863 23863 'Dand5' mRNA 403 369 372 14.91 13.47 14.61 6.83 6.54 6.76 14.33 6.71 212 198 203 381.3333333 204.3333333 5.45E-10 -0.912450325 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0016015///morphogen activity GO:0003140///determination of left/right asymmetry in lateral mesoderm+++GO:0003281///ventricular septum development+++GO:0003283///atrial septum development+++GO:0007368///determination of left/right symmetry+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0038101///sequestering of nodal from receptor via nodal binding+++GO:0061371///determination of heart left/right asymmetry+++GO:1900108///negative regulation of nodal signaling pathway+++GO:1900146///negative regulation of nodal signaling pathway involved in determination of left/right asymmetry+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:1900176///negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry 238662 238662 'Spata31d1b' mRNA 0.01 9 0 0 0.11 0 0 0 0.03 0.036666667 0.01 0 0 2.5 3.003333333 0.833333333 0.472838893 -2.130381828 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 238663 238663 'Spata31d1d' mRNA 6 7 9 0.08 0.1 0.13 0.01 0.06 0.01 0.103333333 0.026666667 1 5 1 7.333333333 2.333333333 0.208716763 -1.662634014 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 238673 238673 'Zfp367' mRNA 437 393 460 7.36 6.49 8.2 11.63 10.19 10.6 7.35 10.80666667 810 685 709 430 734.6666667 8.09E-10 0.756391491 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 238680 238680 'Cntnap3' mRNA 15 13 12 0.22 0.19 0.15 0.07 0.08 0.06 0.186666667 0.07 7 6 4 13.33333333 5.666666667 0.155381812 -1.245839198 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043204///perikaryon GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0008150///biological_process 238690 238690 'Zfp458' mRNA 301.38 298.58 290.88 2.78 2.81 2.94 2.55 2.69 2.6 2.843333333 2.613333333 303.99 302.44 320.88 296.9466667 309.1033333 0.824691356 0.045769291 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 238692 238692 'Zfp874a' mRNA 266.77 280.12 284.74 4.5 4.65 5.09 2.94 3.5 2.85 4.746666667 3.096666667 200.78 232.92 188.38 277.21 207.36 0.015137779 -0.432966416 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 238693 238693 'Zfp58' mRNA 230 244 229 5.46 5.7 5.77 4.19 3.85 4.07 5.643333333 4.036666667 203 182 191 234.3333333 192 0.103434819 -0.299665599 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 23871 23871 'Ets1' mRNA 279 276 254 2.95 2.87 2.99 4.71 5.22 5.49 2.936666667 5.14 498 544 577 269.6666667 539.6666667 5.31E-14 0.991404142 04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04218///Cellular senescence+++04320///Dorso-ventral axis formation+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035035///histone acetyltransferase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001666///response to hypoxia+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0021854///hypothalamus development+++GO:0021983///pituitary gland development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030578///PML body organization+++GO:0032355///response to estradiol+++GO:0034616///response to laminar fluid shear stress+++GO:0042981///regulation of apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0044849///estrous cycle+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045765///regulation of angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0045786///negative regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046677///response to antibiotic+++GO:0048870///cell motility+++GO:0050728///negative regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051272///positive regulation of cellular component movement+++GO:0060055///angiogenesis involved in wound healing+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070555///response to interleukin-1+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell" 23872 23872 'Ets2' mRNA 1067 1042 1102 16.3 15.66 17.86 16.65 16.28 17.01 16.60666667 16.64666667 1254 1198 1241 1070.333333 1231 0.048881846 0.187997849 04014///Ras signaling pathway+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019904///protein domain specific binding+++GO:0035259///glucocorticoid receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001712///ectodermal cell fate commitment+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007498///mesoderm development+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090009///primitive streak formation" 238722 238722 'Zfp72' mRNA 173 167 183 2.25 2.13 2.52 1.41 1.34 1.55 2.3 1.433333333 125 116 133 174.3333333 124.6666667 0.020844615 -0.49810527 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0044794///positive regulation by host of viral process" 238725 238725 'Gpr150' mRNA 7 5 9 0.18 0.13 0.25 0.23 0.45 0.69 0.186666667 0.456666667 10 19 29 7 19.33333333 0.064683294 1.451193406 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 238726 238726 'Fam81b' mRNA 318 370 329 11.66 13.38 12.8 0.96 1.08 0.76 12.61333333 0.933333333 30 33 23 339 28.66666667 4.50E-54 -3.574877203 GO:0003674///molecular_function GO:0008150///biological_process 23873 23873 'Faim' mRNA 404 462 484 25.06 28.33 31.85 36.1 36.36 33.28 28.41333333 35.24666667 662 650 590 450 634 1.96E-04 0.479811157 GO:0005737///cytoplasm GO:0006915///apoptotic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0043066///negative regulation of apoptotic process+++GO:0050769///positive regulation of neurogenesis+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 23874 23874 'Farsb' mRNA 1256.84 1334.05 1310.93 31.2 32.53 34.57 35.81 37.56 35 32.76666667 36.12333333 1633.63 1701.81 1559.56 1300.606667 1631.666667 2.32E-04 0.31502233 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009328///phenylalanine-tRNA ligase complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004826///phenylalanine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0051290///protein heterotetramerization 23876 23876 'Fbln5' mRNA 1877 1980 1940 37.57 39.48 41.5 19.36 20.52 19.99 39.51666667 19.95666667 1115 1121 1110 1932.333333 1115.333333 4.87E-25 -0.805291394 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0042803///protein homodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0007155///cell adhesion+++GO:0016525///negative regulation of angiogenesis+++GO:0030198///extracellular matrix organization+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034394///protein localization to cell surface+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046903///secretion+++GO:0048251///elastic fiber assembly+++GO:0098867///intramembranous bone growth+++GO:2000121///regulation of removal of superoxide radicals 23877 23877 'Fiz1' mRNA 838 952 935 17.91 20.24 21.3 16.02 14.17 14.37 19.81666667 14.85333333 857 741 744 908.3333333 780.6666667 0.038326424 -0.232961701 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0001934///positive regulation of protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II 23879 23879 'Fxr2' mRNA 611 602 591 11.18 10.9 11.52 9.68 10.78 10.45 11.2 10.30333333 608 659 638 601.3333333 635 0.633850997 0.067491264 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044326///dendritic spine neck+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:1902737///dendritic filopodium GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0045182///translation regulator activity+++GO:0046982///protein heterodimerization activity "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation+++GO:0051489///regulation of filopodium assembly+++GO:2001022///positive regulation of response to DNA damage stimulus" 238799 238799 'Tnpo1' mRNA 722 757 556.87 7.39 7.67 6.11 9.77 8.69 10.05 7.056666667 9.503333333 1050 917 1059 678.6233333 1008.666667 2.64E-07 0.565255025 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0031267///small GTPase binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport 23880 23880 'Fyb' mRNA 230 257 263 3.38 3.57 4.09 23.45 21.93 21.42 3.68 22.26666667 1815 1601 1592 250 1669.333333 3.90E-151 2.725214056 04015///Rap1 signaling pathway+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0044877///protein-containing complex binding GO:0006955///immune response+++GO:0007229///integrin-mediated signaling pathway+++GO:0045576///mast cell activation+++GO:0050852///T cell receptor signaling pathway+++GO:0072659///protein localization to plasma membrane 238803 238803 'Zfp366' mRNA 11 22 25 0.22 0.43 0.53 0.82 0.5 0.47 0.393333333 0.596666667 47 28 26 19.33333333 33.66666667 0.180840133 0.775527237 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0030331///estrogen receptor binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0043627///response to estrogen 23881 23881 'G3bp2' mRNA 4497.23 4571.72 4429.28 56.81 56.85 59.41 49.49 48.85 50.37 57.69 49.57 4507.33 4341.76 4434.75 4499.41 4427.946667 0.63926766 -0.035376305 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0002376///immune system process+++GO:0007264///small GTPase mediated signal transduction+++GO:0034063///stress granule assembly+++GO:0045087///innate immune response+++GO:0051028///mRNA transport+++GO:0051260///protein homooligomerization+++GO:0062029///positive regulation of stress granule assembly 23882 23882 'Gadd45g' mRNA 477 488 548 27.7 28.01 33.77 25.82 24.04 24.41 29.82666667 24.75666667 510 463 466 504.3333333 479.6666667 0.590917742 -0.088406957 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0000185///activation of MAPKKK activity+++GO:0000186///activation of MAPKK activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0032609///interferon-gamma production+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045063///T-helper 1 cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0051726///regulation of cell cycle+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1900745///positive regulation of p38MAPK cascade 238831 238831 'Ppwd1' mRNA 272.44 285.54 258.65 5.41 5.58 5.37 4.28 3.65 4.66 5.453333333 4.196666667 234.52 200.98 248.38 272.21 227.96 0.131796577 -0.268461092 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016604///nuclear body+++GO:0071013///catalytic step 2 spliceosome GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 23885 23885 'Gmcl1' mRNA 432 542 178 8.05 9.96 3.52 3.23 2.96 3.97 7.176666667 3.386666667 200 178 237 384 205 0.069147489 -0.895878361 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016363///nuclear matrix GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation" 23886 23886 'Gdf15' mRNA 98 86 80 4.16 3.64 3.63 8.96 7.67 9.29 3.81 8.64 243 204 243 88 230 1.02E-11 1.374934556 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0042803///protein homodimerization activity+++GO:0070700///BMP receptor binding GO:0000187///activation of MAPK activity+++GO:0002023///reduction of food intake in response to dietary excess+++GO:0007165///signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0040015///negative regulation of multicellular organism growth+++GO:0043410///positive regulation of MAPK cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060395///SMAD protein signal transduction+++GO:0060400///negative regulation of growth hormone receptor signaling pathway+++GO:1901741///positive regulation of myoblast fusion 23887 23887 'Ggt5' mRNA 40 43 49 0.98 0.76 0.94 3.04 2.82 3.39 0.893333333 3.083333333 177 186 180 44 181 1.63E-16 2.026745035 00430///Taurine and hypotaurine metabolism+++00480///Glutathione metabolism+++00590///Arachidonic acid metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane "GO:0000048///peptidyltransferase activity+++GO:0002951///leukotriene-C(4) hydrolase+++GO:0008233///peptidase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0036374///glutathione hydrolase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0103068///leukotriene C4 gamma-glutamyl transferase activity" GO:0006412///translation+++GO:0006508///proteolysis+++GO:0006520///cellular amino acid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006751///glutathione catabolic process+++GO:0006954///inflammatory response+++GO:0007283///spermatogenesis+++GO:0019370///leukotriene biosynthetic process+++GO:0032355///response to estradiol+++GO:0032496///response to lipopolysaccharide+++GO:0034612///response to tumor necrosis factor+++GO:1901750///leukotriene D4 biosynthetic process 238871 238871 'Pde4d' mRNA 1160.49 1184.05 1204.19 4.95 5.21 5.86 3.02 2.6 2.71 5.34 2.776666667 720.5 595.58 634.01 1182.91 650.03 3.80E-19 -0.878927372 "00230///Purine metabolism+++04024///cAMP signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05032///Morphine addiction" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030016///myofibril+++GO:0032991///protein-containing complex+++GO:0034704///calcium channel complex+++GO:0034705///potassium channel complex+++GO:0048471///perinuclear region of cytoplasm "GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030552///cAMP binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding+++GO:0097110///scaffold protein binding+++GO:1901363///heterocyclic compound binding" GO:0001934///positive regulation of protein phosphorylation+++GO:0002027///regulation of heart rate+++GO:0006198///cAMP catabolic process+++GO:0006939///smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007568///aging+++GO:0007613///memory+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030593///neutrophil chemotaxis+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0034622///cellular protein-containing complex assembly+++GO:0035264///multicellular organism growth+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045822///negative regulation of heart contraction+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0050900///leukocyte migration+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0061028///establishment of endothelial barrier+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071320///cellular response to cAMP+++GO:0071872///cellular response to epinephrine stimulus+++GO:0071875///adrenergic receptor signaling pathway+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:1901898///negative regulation of relaxation of cardiac muscle 238875 238875 'Gapt' mRNA 1 4 0 0.03 0.11 0 1.64 2.42 1.38 0.046666667 1.813333333 68 97 55 1.666666667 73.33333333 2.52E-12 5.458339537 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001782///B cell homeostasis+++GO:0002322///B cell proliferation involved in immune response+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0042113///B cell activation 23888 23888 'Gpc6' mRNA 1158.04 1245.9 1106 7.82 8.35 8.11 1.36 1.33 1.36 8.093333333 1.35 246.03 224 231 1169.98 233.6766667 7.66E-109 -2.334547313 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0098978///glutamatergic synapse GO:0009966///regulation of signal transduction+++GO:0016477///cell migration+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0099560///synaptic membrane adhesion+++GO:1905475///regulation of protein localization to membrane+++GO:1905606///regulation of presynapse assembly 238880 238880 'Actbl2' mRNA 4 1 4 0.08 0.02 0.09 0 0 0.05 0.063333333 0.016666667 0 0 3 3 1 0.491892501 -1.606965456 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0030424///axon+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0098973///structural constituent of postsynaptic actin cytoskeleton GO:0007409///axonogenesis+++GO:0048870///cell motility+++GO:0098974///postsynaptic actin cytoskeleton organization 238896 238896 'Cdc20b' mRNA 1 0 0 0.04 0 0 0 0 0.03 0.013333333 0.01 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005680///anaphase-promoting complex GO:0010997///anaphase-promoting complex binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990757///ubiquitin ligase activator activity GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:1905786///positive regulation of anaphase-promoting complex-dependent catabolic process 23890 23890 'Gpr34' mRNA 52 52 53 1.34 1.37 1.63 11.51 9.79 10.31 1.446666667 10.53666667 463 380 391 52.33333333 411.3333333 1.90E-54 2.960918216 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway 23892 23892 'Grem1' mRNA 4 10 7 0.14 0.35 0.26 0.37 0.13 0.13 0.25 0.21 12 4 4 7 6.666666667 0.945253894 -0.090655762 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface GO:0005125///cytokine activity+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0036122///BMP binding+++GO:0042803///protein homodimerization activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048018///receptor ligand activity "GO:0000902///cell morphogenesis+++GO:0001525///angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002092///positive regulation of receptor internalization+++GO:0002689///negative regulation of leukocyte chemotaxis+++GO:0003257///positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007267///cell-cell signaling+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0009954///proximal/distal pattern formation+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0030199///collagen fibril organization+++GO:0030308///negative regulation of cell growth+++GO:0030326///embryonic limb morphogenesis+++GO:0030502///negative regulation of bone mineralization+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0043066///negative regulation of apoptotic process+++GO:0043542///endothelial cell migration+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046851///negative regulation of bone remodeling+++GO:0048263///determination of dorsal identity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051893///regulation of focal adhesion assembly+++GO:0051973///positive regulation of telomerase activity+++GO:0060173///limb development+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060676///ureteric bud formation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0072331///signal transduction by p53 class mediator+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0090291///negative regulation of osteoclast proliferation+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:1900155///negative regulation of bone trabecula formation+++GO:1900158///negative regulation of bone mineralization involved in bone maturation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000727///positive regulation of cardiac muscle cell differentiation" 23893 23893 'Grem2' mRNA 11 5 13 0.16 0.07 0.2 0.03 0 0 0.143333333 0.01 2 0 0 9.666666667 0.666666667 0.012534414 -3.895198857 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008201///heparin binding+++GO:0036122///BMP binding+++GO:0042802///identical protein binding+++GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0009887///animal organ morphogenesis+++GO:0010172///embryonic body morphogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0048263///determination of dorsal identity+++GO:0060300///regulation of cytokine activity 23894 23894 'Gtf2h2' mRNA 310 379 324 11.38 13.82 12.56 15.73 14.02 13.98 12.58666667 14.57666667 496 435 430 337.6666667 453.6666667 0.003112255 0.414365695 03022///Basal transcription factors+++03420///Nucleotide excision repair+++05203///Viral carcinogenesis GO:0000438///core TFIIH complex portion of holo TFIIH complex+++GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0016607///nuclear speck GO:0008270///zinc ion binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding "GO:0002031///G protein-coupled receptor internalization+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:1905776///positive regulation of DNA helicase activity" 23897 23897 'Hax1' mRNA 1385 1438 1353 74.85 76.34 77.14 90.84 95.74 96.42 76.11 94.33333333 1928 1982 1959 1392 1956.333333 7.81E-11 0.479973441 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030027///lamellipodium+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0019966///interleukin-1 binding+++GO:0047485///protein N-terminus binding GO:0007166///cell surface receptor signaling pathway+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030833///regulation of actin filament polymerization+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071345///cellular response to cytokine stimulus+++GO:2000251///positive regulation of actin cytoskeleton reorganization 238988 238988 'Erc2' mRNA 351 409 353 3.35 3.62 3.61 0.79 0.7 0.72 3.526666667 0.736666667 102 83 94 371 93 4.70E-31 -2.007650846 GO:0005737///cytoplasm+++GO:0005798///Golgi-associated vesicle+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0044877///protein-containing complex binding+++GO:0098882///structural constituent of presynaptic active zone GO:0007274///neuromuscular synaptic transmission+++GO:0016082///synaptic vesicle priming+++GO:0048167///regulation of synaptic plasticity+++GO:0048790///maintenance of presynaptic active zone structure 23900 23900 'Hcst' mRNA 4 6 3 0.84 1.26 0.67 9.61 9.92 12.51 0.923333333 10.68 52 52 65 4.333333333 56.33333333 1.74E-10 3.694104718 04650///Natural killer cell mediated cytotoxicity GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding GO:0006468///protein phosphorylation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0050776///regulation of immune response 239017 239017 'Ogdhl' mRNA 2796 2660 2560 41.68 42.29 41.06 17.42 17.2 15.63 41.67666667 16.75 1367 1319 1197 2672 1294.333333 1.10E-46 -1.057404651 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0045252///oxoglutarate dehydrogenase complex "GO:0004591///oxoglutarate dehydrogenase (succinyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0030976///thiamine pyrophosphate binding" GO:0006099///tricarboxylic acid cycle+++GO:0006103///2-oxoglutarate metabolic process 239027 239027 'Arhgap22' mRNA 45 54 50 0.98 1.16 1.37 6.86 7.13 6.58 1.17 6.856666667 370 382 355 49.66666667 369 3.40E-49 2.882177456 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse GO:0005096///GTPase activator activity GO:0001525///angiogenesis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity+++GO:0099175///regulation of postsynapse organization 23908 23908 'Hs2st1' mRNA 996.17 1023.7 931.37 3.24 3.39 3.27 3.68 3.02 3.4 3.3 3.366666667 1128.66 936.77 1056.85 983.7466667 1040.76 0.553894268 0.068839378 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004394///heparan sulfate 2-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity "GO:0010467///gene expression+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification+++GO:0030202///heparin metabolic process+++GO:0060676///ureteric bud formation" 239081 239081 'Tlr11' mRNA 2 0 0 0.03 0 0 0.04 0.06 0.05 0.01 0.05 3 4 3 0.666666667 3.333333333 0.297482578 2.327479338 05145///Toxoplasmosis GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0038023///signaling receptor activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0009617///response to bacterium+++GO:0045087///innate immune response 239083 239083 'Ccnb1ip1' mRNA 8 8 6 0.31 0.31 0.25 0.31 0.17 0.32 0.29 0.266666667 9 5 9 7.333333333 7.666666667 0.966599171 0.05391138 GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001825///blastocyst formation+++GO:0007131///reciprocal meiotic recombination+++GO:0007286///spermatid development+++GO:0016567///protein ubiquitination+++GO:0051026///chiasma assembly+++GO:0051321///meiotic cell cycle 239096 239096 'Cdh24' mRNA 203 176 116 3.91 3.57 2.68 1.96 2.13 2.53 3.386666667 2.206666667 112 119 132 165 121 0.075675896 -0.449555066 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0008013///beta-catenin binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0070097///delta-catenin binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 239099 239099 'Homez' mRNA 798.23 794.51 856.96 11.96 11.62 13.61 16.61 16.26 16.35 12.39666667 16.40666667 1213.99 1170.89 1172.91 816.5666667 1185.93 3.53E-08 0.523985998 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 239102 239102 'Zfhx2' mRNA 917 885 802 5.02 4.69 4.67 4.71 4.1 4.36 4.793333333 4.39 1006 845 892 868 914.3333333 0.607496395 0.063561304 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0030534///adult behavior+++GO:0045664///regulation of neuron differentiation+++GO:0051930///regulation of sensory perception of pain" 239114 239114 'Il17d' mRNA 18 29 21 0.9 1.43 1.12 0.61 0.49 0.41 1.15 0.503333333 14 11 9 22.66666667 11.33333333 0.123734774 -1.010877227 04060///Cytokine-cytokine receptor interaction+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0042803///protein homodimerization activity+++GO:0048018///receptor ligand activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1903707///negative regulation of hemopoiesis 23912 23912 'Rhof' mRNA 1367 1267 1027 10.63 9.42 8.46 4.49 4.27 4.77 9.503333333 4.51 697 638 720 1220.333333 685 1.92E-16 -0.84069315 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization 239122 239122 'Setdb2' mRNA 109.59 146 203 2.04 2.64 3.99 3.42 3.04 3.24 2.89 3.233333333 213.51 185.07 195.24 152.8633333 197.94 0.194887642 0.348621928 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific) "GO:0000278///mitotic cell cycle+++GO:0001947///heart looping+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007275///multicellular organism development+++GO:0010629///negative regulation of gene expression+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0051567///histone H3-K9 methylation+++GO:0070828///heterochromatin organization+++GO:0070986///left/right axis specification+++GO:0090309///positive regulation of methylation-dependent chromatin silencing" 239126 239126 'C1qtnf9' mRNA 7 10 3 0.22 0.3 0.1 0.16 0.4 0.43 0.206666667 0.33 6 15 16 6.666666667 12.33333333 0.361538628 0.899150661 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0019395///fatty acid oxidation+++GO:0045792///negative regulation of cell size+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0097009///energy homeostasis+++GO:1900078///positive regulation of cellular response to insulin stimulus 239133 239133 'Dleu7' mRNA 6 11 6 0.27 0.49 0.29 0 0 0.04 0.35 0.013333333 0 0 1 7.666666667 0.333333333 0.011524366 -4.422421207 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 239157 239157 'Pnma2' mRNA 16 7 10 0.18 0.08 0.13 0.07 0.25 0.15 0.13 0.156666667 7 24 14 11 15 0.640356316 0.444917798 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 239167 239167 'Synb' mRNA 4 3 0 0.08 0.06 0 0 0 0 0.046666667 0 0 0 0 2.333333333 0 0.236361545 -3.642213188 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0000768///syncytium formation by plasma membrane fusion+++GO:0006949///syncytium formation+++GO:0007275///multicellular organism development+++GO:0007519///skeletal muscle tissue development+++GO:0007520///myoblast fusion+++GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0060716///labyrinthine layer blood vessel development 23917 23917 'Impdh1' mRNA 444 450 364 9.99 10.05 8.84 12.61 12.24 11.44 9.626666667 12.09666667 641 613 572 419.3333333 608.6666667 9.71E-06 0.528891204 00230///Purine metabolism+++00983///Drug metabolism - other enzymes GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0003938///IMP dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006183///GTP biosynthetic process+++GO:0032263///GMP salvage+++GO:0046651///lymphocyte proliferation+++GO:0097294///'de novo' XMP biosynthetic process 239170 239170 'Fam160b2' mRNA 929.69 1002.13 836.98 12.68 13.35 12.09 7.9 8.21 8.7 12.70666667 8.27 671.15 678.61 713.23 922.9333333 687.6633333 1.14E-05 -0.433073311 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 23918 23918 'Impdh2' mRNA 859 875 783 29.14 29.23 28.15 36.52 36.07 37.77 28.84 36.78666667 1233 1192 1238 839 1221 3.28E-10 0.531002417 00230///Purine metabolism+++00983///Drug metabolism - other enzymes GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0003938///IMP dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006183///GTP biosynthetic process+++GO:0007623///circadian rhythm+++GO:0032263///GMP salvage+++GO:0046651///lymphocyte proliferation+++GO:0060041///retina development in camera-type eye+++GO:0071353///cellular response to interleukin-4+++GO:0097294///'de novo' XMP biosynthetic process 239188 239188 'Enox1' mRNA 157 153 161 2.24 2.21 2.51 0.19 0.19 0.23 2.32 0.203333333 16 15 17 157 16 1.17E-25 -3.308337384 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003756///protein disulfide isomerase activity+++GO:0003954///NADH dehydrogenase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity GO:0007624///ultradian rhythm+++GO:0008150///biological_process+++GO:0048511///rhythmic process 23919 23919 'Insl5' mRNA 12 16 13 1.04 1.57 1 0.37 0.25 0.15 1.203333333 0.256666667 4 5 2 13.66666667 3.666666667 0.039182639 -1.907526123 04080///Neuroactive ligand-receptor interaction+++04926///Relaxin signaling pathway GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity GO:0007165///signal transduction+++GO:2000253///positive regulation of feeding behavior 23920 23920 'Insrr' mRNA 9 3 2 0.1 0.03 0.03 0.09 0.02 0.07 0.053333333 0.06 9 2 7 4.666666667 6 0.823271691 0.35534413 04810///Regulation of actin cytoskeleton+++05215///Prostate cancer GO:0005887///integral component of plasma membrane+++GO:0005899///insulin receptor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005009///insulin-activated receptor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043560///insulin receptor substrate binding GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0008286///insulin receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030238///male sex determination+++GO:0031532///actin cytoskeleton reorganization+++GO:0033674///positive regulation of kinase activity+++GO:0046777///protein autophosphorylation+++GO:0071469///cellular response to alkaline pH 23921 23921 'Sh2b2' mRNA 48 27 32 1.06 0.58 0.72 2.06 2.01 1.95 0.786666667 2.006666667 113 110 101 35.66666667 108 4.71E-07 1.58733165 04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding+++GO:0035591///signaling adaptor activity+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding GO:0001922///B-1 B cell homeostasis+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008286///insulin receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0030036///actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0042593///glucose homeostasis+++GO:0046325///negative regulation of glucose import+++GO:0046578///regulation of Ras protein signal transduction+++GO:0050776///regulation of immune response+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0050873///brown fat cell differentiation 239217 239217 'Kctd12' mRNA 387 401 369 3.39 3.45 3.43 8.47 7.82 8.82 3.423333333 8.37 1114 1005 1123 385.6666667 1080.666667 3.29E-49 1.47503302 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0051260///protein homooligomerization 23922 23922 'Jtb' mRNA 1564 1599 1486 88.62 89.53 89.34 95.09 94.53 91.62 89.16333333 93.74666667 1925 1866 1793 1549.666667 1861.333333 6.33E-04 0.253099468 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody GO:0019901///protein kinase binding GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008637///apoptotic mitochondrial changes+++GO:0042127///regulation of cell proliferation+++GO:0045860///positive regulation of protein kinase activity+++GO:0051301///cell division 23923 23923 'Aadat' mRNA 6 6 7 0.19 0.19 0.24 0.03 0.09 0.12 0.206666667 0.08 1 3 4 6.333333333 2.666666667 0.352835705 -1.257783217 00300///Lysine biosynthesis+++00310///Lysine degradation+++00380///Tryptophan metabolism+++01210///2-Oxocarboxylic acid metabolism GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042803///protein homodimerization activity+++GO:0047536///2-aminoadipate transaminase activity GO:0006103///2-oxoglutarate metabolic process+++GO:0006536///glutamate metabolic process+++GO:0009058///biosynthetic process+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0070189///kynurenine metabolic process+++GO:0097052///L-kynurenine metabolic process+++GO:1901605///alpha-amino acid metabolic process 23924 23924 'Katna1' mRNA 872 941 902 28.03 29.74 30.78 25.67 27.13 25.09 29.51666667 25.96333333 921 945 866 905 910.6666667 0.988499515 -0.002928648 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0043025///neuronal cell body+++GO:0097431///mitotic spindle pole GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0046982///protein heterodimerization activity+++GO:0070840///dynein complex binding GO:0001578///microtubule bundle formation+++GO:0001764///neuron migration+++GO:0007049///cell cycle+++GO:0008104///protein localization+++GO:0010977///negative regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0031122///cytoplasmic microtubule organization+++GO:0051013///microtubule severing+++GO:0051301///cell division 239250 239250 'Slitrk6' mRNA 2642 2689 2565 33.04 33.13 33.95 6.19 6.05 5.03 33.37333333 5.756666667 565 548 448 2632 520.3333333 6.60E-156 -2.350874829 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery GO:0003674///molecular_function GO:0001964///startle response+++GO:0002088///lens development in camera-type eye+++GO:0002093///auditory receptor cell morphogenesis+++GO:0007409///axonogenesis+++GO:0007416///synapse assembly+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0008344///adult locomotory behavior+++GO:0021562///vestibulocochlear nerve development+++GO:0031223///auditory behavior+++GO:0035264///multicellular organism growth+++GO:0042472///inner ear morphogenesis+++GO:0043010///camera-type eye development+++GO:0048812///neuron projection morphogenesis+++GO:0050896///response to stimulus+++GO:0051965///positive regulation of synapse assembly+++GO:0060005///vestibular reflex+++GO:0060007///linear vestibuloocular reflex+++GO:0060384///innervation+++GO:0090102///cochlea development+++GO:1905606///regulation of presynapse assembly 239273 239273 'Abcc4' mRNA 834.68 882.45 824.81 7.74 8.04 8.11 5.93 5.65 5.96 7.963333333 5.846666667 735.35 685.88 717.3 847.3133333 712.8433333 0.009101583 -0.261058919 01523///Antifolate resistance+++02010///ABC transporters+++04024///cAMP signaling pathway+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031088///platelet dense granule membrane+++GO:0098591///external side of apical plasma membrane "GO:0000166///nucleotide binding+++GO:0001409///guanine nucleotide transmembrane transporter activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015132///prostaglandin transmembrane transporter activity+++GO:0015143///urate transmembrane transporter activity+++GO:0015216///purine nucleotide transmembrane transporter activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0015432///bile acid-exporting ATPase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0034634///glutathione transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity" GO:0006855///drug transmembrane transport+++GO:0010033///response to organic substance+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0015721///bile acid and bile salt transport+++GO:0015732///prostaglandin transport+++GO:0015747///urate transport+++GO:0032310///prostaglandin secretion+++GO:0034775///glutathione transmembrane transport+++GO:0038183///bile acid signaling pathway+++GO:0042493///response to drug+++GO:0042908///xenobiotic transport+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0055085///transmembrane transport+++GO:0060271///cilium assembly+++GO:0070730///cAMP transport+++GO:0071716///leukotriene transport+++GO:0140115///export across plasma membrane+++GO:1903790///guanine nucleotide transmembrane transport 23928 23928 'Lamc3' mRNA 408.52 463.94 452.01 2.53 2.83 2.97 0.72 0.72 0.72 2.776666667 0.72 133.67 130.34 129.23 441.49 131.08 6.92E-30 -1.76802868 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05145///Toxoplasmosis+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016020///membrane GO:0000904///cell morphogenesis involved in differentiation+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0014002///astrocyte development+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0060041///retina development in camera-type eye 239318 239318 'Plcxd3' mRNA 80 85 90 2.42 2.53 2.88 3.31 2.56 3.26 2.61 3.043333333 126 95 120 85 113.6666667 0.148360669 0.403528385 GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0016042///lipid catabolic process 239319 239319 'Card6' mRNA 354 326 391 3.66 3.38 4.47 3.49 3.25 3.2 3.836666667 3.313333333 391 348 354 357 364.3333333 0.950946368 0.012622369 04621///NOD-like receptor signaling pathway GO:0005737///cytoplasm GO:0003674///molecular_function GO:0042981///regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling 239336 239336 'Rxfp3' mRNA 62 44 38 0.78 0.55 0.51 0.82 1.08 0.91 0.613333333 0.936666667 75 96 80 48 83.66666667 0.017594924 0.796520909 04080///Neuroactive ligand-receptor interaction+++04926///Relaxin signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 239337 239337 'Adamts12' mRNA 52 63 49 0.32 0.38 0.32 0.29 0.35 0.37 0.34 0.336666667 55 65 67 54.66666667 62.33333333 0.664694708 0.182253746 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001503///ossification+++GO:0002062///chondrocyte differentiation+++GO:0006029///proteoglycan metabolic process+++GO:0006508///proteolysis+++GO:0007160///cell-matrix adhesion+++GO:0016477///cell migration+++GO:0030167///proteoglycan catabolic process+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0043931///ossification involved in bone maturation+++GO:0050727///regulation of inflammatory response+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071773///cellular response to BMP stimulus+++GO:1901509///regulation of endothelial tube morphogenesis+++GO:1902203///negative regulation of hepatocyte growth factor receptor signaling pathway+++GO:1902548///negative regulation of cellular response to vascular endothelial growth factor stimulus+++GO:2001113///negative regulation of cellular response to hepatocyte growth factor stimulus 23934 23934 'Ly6h' mRNA 183 176 122 11.99 11.35 9.12 0.58 1.12 1.63 10.82 1.11 12 18 30 160.3333333 20 1.18E-19 -3.00468051 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 23936 23936 'Lynx1' mRNA 534 532 484 7.3 7.15 7.02 8.37 7.21 8.08 7.156666667 7.886666667 705 593 659 516.6666667 652.3333333 0.004784224 0.324733034 04080///Neuroactive ligand-receptor interaction GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031225///anchored component of membrane+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008200///ion channel inhibitor activity+++GO:0030548///acetylcholine receptor regulator activity+++GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding "GO:0007271///synaptic transmission, cholinergic+++GO:0099601///regulation of neurotransmitter receptor activity+++GO:2000272///negative regulation of signaling receptor activity" 239364 239364 'Tspyl5' mRNA 375 364 147 5.05 4.82 2.1 0.73 1.09 0.69 3.99 0.836666667 62 91 57 295.3333333 70 1.45E-12 -2.067584794 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0040008///regulation of growth+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071480///cellular response to gamma radiation 239368 239368 'Erich5' mRNA 136 154 103.03 3.2 3.57 2.57 0.49 0.5 0.47 3.113333333 0.486666667 24 24 22.07 131.01 23.35666667 1.12E-15 -2.493961594 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 23937 23937 'Mab21l2' mRNA 128 107 118 3.23 2.66 3.15 2.87 2.38 2.01 3.013333333 2.42 131 106 89 117.6666667 108.6666667 0.690584221 -0.12999595 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001654///eye development+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0010172///embryonic body morphogenesis+++GO:0043010///camera-type eye development 23938 23938 'Map2k5' mRNA 1139.85 1193.07 1009.86 23.6 24 21.83 15.46 15.78 15.15 23.14333333 15.46333333 880.56 876.97 865.64 1114.26 874.39 5.69E-05 -0.359295989 04010///MAPK signaling pathway+++04540///Gap junction+++04722///Neurotrophin signaling pathway+++04921///Oxytocin signaling pathway+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032717///negative regulation of interleukin-8 production+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051247///positive regulation of protein metabolic process+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070375///ERK5 cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 23939 23939 'Mapk7' mRNA 376 395 321 6.67 6.86 6 10.72 9.5 10.88 6.51 10.36666667 696 602 687 364 661.6666667 6.15E-13 0.85260556 04010///MAPK signaling pathway+++04540///Gap junction+++04657///IL-17 signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++05206///MicroRNAs in cancer+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0043066///negative regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045765///regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0051247///positive regulation of protein metabolic process+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070375///ERK5 cascade+++GO:0070377///negative regulation of ERK5 cascade+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071363///cellular response to growth factor stimulus+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 239393 239393 'Lrp12' mRNA 248 267 224 3.1 3.27 2.96 6.91 5.69 6.86 3.11 6.486666667 636 512 613 246.3333333 587 8.62E-21 1.241788491 GO:0005887///integral component of plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001764///neuron migration+++GO:0006897///endocytosis+++GO:0031175///neuron projection development 239405 239405 'Rspo2' mRNA 331 336 257 5.09 5.1 4.34 1.67 1.88 1.88 4.843333333 1.81 127 135 143 308 135 7.61E-12 -1.196192813 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0009986///cell surface GO:0005102///signaling receptor binding+++GO:0008201///heparin binding GO:0001649///osteoblast differentiation+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030282///bone mineralization+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0042489///negative regulation of odontogenesis of dentin-containing tooth+++GO:0050896///response to stimulus+++GO:0060173///limb development+++GO:0060437///lung growth+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060535///trachea cartilage morphogenesis+++GO:0071542///dopaminergic neuron differentiation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 239408 239408 'Tmem74' mRNA 0 1 0 0 0.01 0 0.04 0 0.12 0.003333333 0.053333333 1 0 5 0.333333333 2 0.429247014 2.469780566 GO:0000421///autophagosome membrane+++GO:0005575///cellular_component+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0016236///macroautophagy 23942 23942 'Mta2' mRNA 2009 1996 2018 35.59 34.79 37.9 42.17 42.31 41.41 36.09333333 41.96333333 2736 2678 2599 2007.666667 2671 1.23E-08 0.39898663 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016581///NuRD complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006306///DNA methylation+++GO:0006323///DNA packaging+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010762///regulation of fibroblast migration+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 239420 239420 'Csmd3' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0050773///regulation of dendrite development 23943 23943 'Esyt1' mRNA 822 871 463 12.09 12.6 7.22 21.71 29.8 29.45 10.63666667 26.98666667 1699 2278 2232 718.6666667 2069.666667 1.97E-07 1.531035327 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0061817///endoplasmic reticulum-plasma membrane tethering 239435 239435 'Aard' mRNA 69 63 33 3.08 2.77 1.56 4.97 4.7 5.94 2.47 5.203333333 128 118 148 55 131.3333333 1.90E-05 1.254594933 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030324///lung development 23945 23945 'Mgll' mRNA 3562 3633 3432 60.76 60.45 61.17 40.41 37.88 37.52 60.79333333 38.60333333 2784 2520 2547 3542.333333 2617 4.66E-13 -0.449052285 00561///Glycerolipid metabolism+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04923///Regulation of lipolysis in adipocytes GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030424///axon+++GO:0043196///varicosity+++GO:0045202///synapse GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0009966///regulation of signal transduction+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019433///triglyceride catabolic process+++GO:0030516///regulation of axon extension+++GO:0045907///positive regulation of vasoconstriction+++GO:0046464///acylglycerol catabolic process+++GO:0050727///regulation of inflammatory response+++GO:0051930///regulation of sensory perception of pain+++GO:0052651///monoacylglycerol catabolic process+++GO:0060292///long-term synaptic depression+++GO:2000124///regulation of endocannabinoid signaling pathway 239463 239463 'Fam83a' mRNA 11.64 13.76 16 0.31 0.37 0.46 0.55 0.42 0.47 0.38 0.48 23.13 17.19 19.1 13.8 19.80666667 0.451377477 0.540912409 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0019901///protein kinase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008283///cell proliferation 23947 23947 'Mid2' mRNA 197 133 157 1.69 1.13 1.45 1.06 0.86 1.08 1.423333333 1 140 115 139 162.3333333 131.3333333 0.20534496 -0.31946487 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0003713///transcription coactivator activity+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding "GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032897///negative regulation of viral transcription+++GO:0035372///protein localization to microtubule+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1902187///negative regulation of viral release from host cell" 23948 23948 'Mmp17' mRNA 25 25 19 0.3 0.29 0.24 0.27 0.33 0.33 0.276666667 0.31 26 31 31 23 29.33333333 0.55806083 0.345287622 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0042756///drinking behavior 23950 23950 'Dnajb6' mRNA 2462 2619 2583 74.55 77.3 82.8 72.37 76.58 71.24 78.21666667 73.39666667 2730 2790 2616 2554.666667 2712 0.395314613 0.073626008 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0048471///perinuclear region of cytoplasm GO:0001671///ATPase activator activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding "GO:0006457///protein folding+++GO:0030036///actin cytoskeleton organization+++GO:0030198///extracellular matrix organization+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045109///intermediate filament organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060710///chorio-allantoic fusion+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0060717///chorion development+++GO:0061077///chaperone-mediated protein folding+++GO:0090084///negative regulation of inclusion body assembly" 239510 239510 'Phf20l1' mRNA 1679 1854 1003 16.7 17.61 8.92 7.06 9.21 9.25 14.41 8.506666667 960 1192 1163 1512 1105 0.124539892 -0.448696262 GO:0005634///nucleus+++GO:0044545///NSL complex GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation" 239528 239528 'Ago2' mRNA 523 504 410 3.43 3.24 2.85 3.98 3.32 4.08 3.173333333 3.793333333 700 570 695 479 655 4.52E-04 0.44225161 04361///Axon regeneration GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005845///mRNA cap binding complex+++GO:0016442///RISC complex+++GO:0030425///dendrite+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070062///extracellular exosome+++GO:0070578///RISC-loading complex+++GO:1990904///ribonucleoprotein complex "GO:0000340///RNA 7-methylguanosine cap binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0035197///siRNA binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0070551///endoribonuclease activity, cleaving siRNA-paired mRNA+++GO:0090624///endoribonuclease activity, cleaving miRNA-paired mRNA+++GO:0098808///mRNA cap binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0009791///post-embryonic development+++GO:0010501///RNA secondary structure unwinding+++GO:0010586///miRNA metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035087///siRNA loading onto RISC involved in RNA interference+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035279///mRNA cleavage involved in gene silencing by miRNA+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045947///negative regulation of translational initiation+++GO:0045975///positive regulation of translation, ncRNA-mediated+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090625///mRNA cleavage involved in gene silencing by siRNA+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901165///positive regulation of trophoblast cell migration+++GO:1905618///positive regulation of miRNA mediated inhibition of translation" 239530 239530 'Gpr20' mRNA 6 12 3.93 0.11 0.29 0.03 0.05 0.03 0.1 0.143333333 0.06 5 6.01 16.67 7.31 9.226666667 0.76697852 0.373514742 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 23954 23954 'Nek3' mRNA 131 147 123 3.67 4.02 3.6 2.92 2.3 2.57 3.763333333 2.596666667 121 93 102 133.6666667 105.3333333 0.158998154 -0.355168385 GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0048812///neuron projection morphogenesis+++GO:0051301///cell division+++GO:0090043///regulation of tubulin deacetylation 239546 239546 'Zfp647' mRNA 126 106 109 3.12 2.59 2.92 1.95 2.09 2.13 2.876666667 2.056666667 98 101 103 113.6666667 100.6666667 0.52572268 -0.186383451 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 23955 23955 'Nek4' mRNA 1025.29 963.25 938.56 13.23 12.36 13.04 7.53 6.98 6.83 12.87666667 7.113333333 666.48 600.43 585.05 975.7 617.32 4.92E-12 -0.672896459 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0035253///ciliary rootlet+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097014///ciliary plasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding "GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:2000772///regulation of cellular senescence+++GO:2001020///regulation of response to DNA damage stimulus" 239552 239552 'Apol8' mRNA 0 4 0 0 0.08 0 0.02 0.06 0.14 0.026666667 0.073333333 1 4 8 1.333333333 4.333333333 0.393367945 1.731115377 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 239554 239554 'Foxred2' mRNA 348.01 386 358 3.64 3.85 3.96 2.58 2.68 2.52 3.816666667 2.593333333 282.31 285.23 264.3 364.0033333 277.28 0.006044529 -0.405579735 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0030433///ubiquitin-dependent ERAD pathway 239555 239555 'Mief1' mRNA 650 592 663 6.82 6.1 7.36 6.39 6 6.53 6.76 6.306666667 702 646 699 635 682.3333333 0.524896009 0.089051521 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005759///mitochondrial matrix+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding GO:0000266///mitochondrial fission+++GO:0070131///positive regulation of mitochondrial translation+++GO:0071456///cellular response to hypoxia+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090314///positive regulation of protein targeting to membrane 239556 239556 'Cacna1i' mRNA 0 2 1 0 0.01 0.01 0 0 0 0.006666667 0 0 0 0 1 0 0.607488248 -2.448949589 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04713///Circadian entrainment+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04934///Cushing syndrome GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0008332///low voltage-gated calcium channel activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0019228///neuronal action potential+++GO:0030317///flagellated sperm motility+++GO:0030431///sleep+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0055085///transmembrane transport+++GO:0060402///calcium ion transport into cytosol+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 239559 239559 'A4galt' mRNA 239 253 232 6.45 6.67 6.64 11.4 10.26 10.31 6.586666667 10.65666667 479 426 429 241.3333333 444.6666667 1.76E-10 0.869793056 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008378///galactosyltransferase activity+++GO:0015643///toxic substance binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0050512///lactosylceramide 4-alpha-galactosyltransferase activity" GO:0001576///globoside biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0007009///plasma membrane organization 23956 23956 'Neu2' mRNA 0 1 0 0 0.04 0 0 0.03 0.07 0.013333333 0.033333333 0 1 2 0.333333333 1 0.729606046 1.480883484 00511///Other glycan degradation+++00600///Sphingolipid metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:1902494///catalytic complex "GO:0004308///exo-alpha-sialidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0052794///exo-alpha-(2->3)-sialidase activity+++GO:0052795///exo-alpha-(2->6)-sialidase activity+++GO:0052796///exo-alpha-(2->8)-sialidase activity" GO:0005975///carbohydrate metabolic process+++GO:0006516///glycoprotein catabolic process+++GO:0006629///lipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process+++GO:0010831///positive regulation of myotube differentiation+++GO:0016042///lipid catabolic process+++GO:0045663///positive regulation of myoblast differentiation+++GO:0051692///cellular oligosaccharide catabolic process 23957 23957 'Nr0b2' mRNA 39 43 33 1.85 2.01 1.66 1.28 1.52 1.41 1.84 1.403333333 31 36 33 38.33333333 33.33333333 0.698542562 -0.208257224 04976///Bile secretion GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007623///circadian rhythm+++GO:0009749///response to glucose+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0015721///bile acid and bile salt transport+++GO:0031100///animal organ regeneration+++GO:0032024///positive regulation of insulin secretion+++GO:0032922///circadian regulation of gene expression+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045471///response to ethanol+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 239570 239570 'Ttc38' mRNA 403.38 412 410 5.83 6.03 6.45 5.47 5.32 5.22 6.103333333 5.336666667 416 406 404 408.46 408.6666667 0.948628687 -0.011356169 GO:0003674///molecular_function GO:0008150///biological_process 23958 23958 'Nr2e3' mRNA 23 14 23 0.75 0.44 0.76 0.86 0.85 0.52 0.65 0.743333333 29 31 20 20 26.66666667 0.537909847 0.397156165 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0042462///eye photoreceptor cell development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development+++GO:0060041///retina development in camera-type eye" 23959 23959 'Nt5e' mRNA 207 244 276 3.14 3.64 4.44 7.47 7.92 7.34 3.74 7.576666667 567 587 539 242.3333333 564.3333333 2.76E-16 1.203791593 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0097060///synaptic membrane "GO:0000166///nucleotide binding+++GO:0008198///ferrous iron binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding" GO:0006196///AMP catabolic process+++GO:0007159///leukocyte cell-cell adhesion+++GO:0009166///nucleotide catabolic process+++GO:0016311///dephosphorylation+++GO:0046032///ADP catabolic process+++GO:0046085///adenosine metabolic process+++GO:0046086///adenosine biosynthetic process+++GO:0050728///negative regulation of inflammatory response 239591 239591 'Ttll8' mRNA 51 76 96 0.71 1.09 1.38 0.23 0.09 0.19 1.06 0.17 14 5 13 74.33333333 10.66666667 2.52E-09 -2.826881923 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0070735///protein-glycine ligase activity+++GO:0070736///protein-glycine ligase activity, initiating" GO:0006464///cellular protein modification process+++GO:0018094///protein polyglycylation+++GO:0060271///cilium assembly 23960 23960 'Oas1g' mRNA 213.3 263.29 236.67 6.05 7.35 7.12 23.6 22.04 25.23 6.84 23.62333333 957.32 872.76 990.46 237.7533333 940.18 1.15E-61 1.973349267 04621///NOD-like receptor signaling pathway+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0048525///negative regulation of viral process+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 239606 239606 'Slc2a13' mRNA 262 290 254 2.12 2.31 2.18 0.58 0.65 0.47 2.203333333 0.566666667 83 90 65 268.6666667 79.33333333 8.09E-19 -1.769990051 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0031090///organelle membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0071944///cell periphery+++GO:0097450///astrocyte end-foot GO:0002020///protease binding+++GO:0005365///myo-inositol transmembrane transporter activity+++GO:0005366///myo-inositol:proton symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0051117///ATPase binding GO:0008643///carbohydrate transport+++GO:0015798///myo-inositol transport+++GO:0055085///transmembrane transport+++GO:1902004///positive regulation of amyloid-beta formation 239618 239618 'Pdzrn4' mRNA 109 144 137 1.52 1.96 2.03 0.18 0.3 0.25 1.836666667 0.243333333 15 24 20 130 19.66666667 1.19E-16 -2.736079705 GO:0005575///cellular_component GO:0046872///metal ion binding 23962 23962 'Oasl2' mRNA 3712 3840 3783 76.18 77.7 81.92 93.51 88.92 88.75 78.6 90.39333333 5245 4861 4805 3778.333333 4970.333333 7.51E-10 0.38232668 05165///Human papillomavirus infection GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009615///response to virus+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060700///regulation of ribonuclease activity+++GO:0070106///interleukin-27-mediated signaling pathway 23963 23963 'Tenm1' mRNA 12 8 2 0.06 0.03 0.01 0.05 0.01 0.03 0.033333333 0.03 14 1 9 7.333333333 8 0.929872398 0.122362231 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0006359///regulation of transcription by RNA polymerase III+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0048666///neuron development+++GO:0051491///positive regulation of filopodium assembly+++GO:0090316///positive regulation of intracellular protein transport 23964 23964 'Tenm2' mRNA 122 155 106 0.42 0.54 0.45 0.4 0.32 0.24 0.47 0.32 115 85 83 127.6666667 94.33333333 0.102167333 -0.445346417 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0007411///axon guidance+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0048666///neuron development+++GO:0051491///positive regulation of filopodium assembly+++GO:0098609///cell-cell adhesion+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex 239647 239647 'Pced1b' mRNA 83 88.16 67.01 1.95 2.15 1.69 1.77 2.22 1.89 1.93 1.96 91.08 112.09 98.85 79.39 100.6733333 0.268432748 0.333021753 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 23965 23965 'Tenm3' mRNA 1196.34 1258.37 1057.58 3.65 3.85 3.57 1.46 1.19 1.28 3.69 1.31 606.46 503.07 489.92 1170.763333 533.15 7.85E-30 -1.146218929 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0048593///camera-type eye morphogenesis+++GO:0048666///neuron development+++GO:1903385///regulation of homophilic cell adhesion 239650 239650 'Ccdc184' mRNA 85 97 74 2.05 2.3 1.89 1.88 2.62 1.88 2.08 2.126666667 90 122 87 85.33333333 99.66666667 0.511009369 0.218474978 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 239652 239652 'Zfp641' mRNA 200 165 179 1.87 1.64 2.02 0.88 1.02 0.82 1.843333333 0.906666667 106 118 89 181.3333333 104.3333333 2.75E-04 -0.809517618 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 239659 239659 'C1ql4' mRNA 1 1 1 0.01 0.1 0.01 0 0 0.03 0.04 0.01 0 0 2 1 0.666666667 0.863328977 -0.591946279 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0045599///negative regulation of fat cell differentiation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 23966 23966 'Tenm4' mRNA 4384 4230 3380 16.69 15.86 13.66 5.15 5.2 4.98 15.40333333 5.11 1558 1526 1460 3998 1514.666667 7.89E-75 -1.40737097 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0001702///gastrulation with mouth forming second+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0031641///regulation of myelination+++GO:0031643///positive regulation of myelination+++GO:0032289///central nervous system myelin formation+++GO:0048666///neuron development+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0060038///cardiac muscle cell proliferation+++GO:0060912///cardiac cell fate specification+++GO:2000543///positive regulation of gastrulation 239667 239667 'Dip2b' mRNA 1443 1464 1052 8.37 8.36 6.55 7.4 6.65 7.26 7.76 7.103333333 1454 1294.6 1386.84 1319.666667 1378.48 0.674221909 0.056320774 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0043014///alpha-tubulin binding GO:0007399///nervous system development+++GO:0030517///negative regulation of axon extension+++GO:2000758///positive regulation of peptidyl-lysine acetylation 23967 23967 'Osr1' mRNA 67 91 78 1.9 2.54 2.34 2.8 2.62 2.31 2.26 2.576666667 113 104 91 78.66666667 102.6666667 0.211388066 0.372017372 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001655///urogenital system development+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001823///mesonephros development+++GO:0002062///chondrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0008406///gonad development+++GO:0009790///embryo development+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0042476///odontogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048389///intermediate mesoderm development+++GO:0048793///pronephros development+++GO:0048863///stem cell differentiation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0071300///cellular response to retinoic acid+++GO:0072075///metanephric mesenchyme development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0072143///mesangial cell development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072166///posterior mesonephric tubule development+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072180///mesonephric duct morphogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0072190///ureter urothelium development+++GO:0072207///metanephric epithelium development+++GO:0072208///metanephric smooth muscle tissue development+++GO:0072234///metanephric nephron tubule development+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072259///metanephric interstitial fibroblast development+++GO:0072268///pattern specification involved in metanephros development+++GO:0072498///embryonic skeletal joint development+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:2000543///positive regulation of gastrulation+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 239673 239673 'Krt90' mRNA 23 17 22 0.51 0.37 0.51 0.06 0.04 0.02 0.463333333 0.04 3 2 1 20.66666667 2 2.16E-04 -3.3873623 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 23968 23968 'Nlrp5' mRNA 1 2 0 0.02 0.03 0 0.01 0.04 0 0.016666667 0.016666667 1 3 0 1 1.333333333 0.883686608 0.444513812 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0045179///apical cortex+++GO:0060473///cortical granule GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding GO:0001701///in utero embryonic development+++GO:0006887///exocytosis+++GO:0007015///actin filament organization+++GO:0007566///embryo implantation+++GO:0009566///fertilization+++GO:0009887///animal organ morphogenesis+++GO:0031647///regulation of protein stability+++GO:0032879///regulation of localization+++GO:0034613///cellular protein localization+++GO:0034622///cellular protein-containing complex assembly+++GO:0040019///positive regulation of embryonic development+++GO:0043487///regulation of RNA stability+++GO:0051293///establishment of spindle localization+++GO:0051302///regulation of cell division+++GO:0051656///establishment of organelle localization+++GO:0060471///cortical granule exocytosis 23969 23969 'Pacsin1' mRNA 799 930 806 10.23 11.73 10.96 2.54 2.93 2.86 10.97333333 2.776666667 227 257 248 845 244 1.99E-50 -1.801624121 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030137///COPI-coated vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098684///photoreceptor ribbon synapse+++GO:0098833///presynaptic endocytic zone+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008092///cytoskeletal protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0045806///negative regulation of endocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048666///neuron development+++GO:0048812///neuron projection morphogenesis+++GO:0072657///protein localization to membrane+++GO:0072659///protein localization to plasma membrane+++GO:0097320///plasma membrane tubulation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1900006///positive regulation of dendrite development 239691 239691 'AU021092' mRNA 119 77 69 5.24 3.42 3.32 4.62 3.99 6.42 3.993333333 5.01 121 101 159 88.33333333 127 0.089764079 0.516673503 GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0016020///membrane GO:0042803///protein homodimerization activity GO:0008150///biological_process 23970 23970 'Pacsin2' mRNA 2909.27 3005 2350 48.77 49.67 42.39 42.04 48.95 47.31 46.94333333 46.1 2876 3268 3139 2754.756667 3094.333333 0.073613892 0.162138515 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005911///cell-cell junction+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0019898///extrinsic component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008092///cytoskeletal protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0070300///phosphatidic acid binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0030100///regulation of endocytosis+++GO:0036010///protein localization to endosome+++GO:0045806///negative regulation of endocytosis+++GO:0048858///cell projection morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0070836///caveola assembly+++GO:0072584///caveolin-mediated endocytosis+++GO:0097320///plasma membrane tubulation 239706 239706 'Mettl22' mRNA 272 215 262 12.68 9.91 12.9 8.23 8.95 9.89 11.83 9.023333333 203 217 236 249.6666667 218.6666667 0.326015132 -0.20514008 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0031072///heat shock protein binding GO:0006479///protein methylation+++GO:0032259///methylation 23971 23971 'Papss1' mRNA 3202 3240 3128 68.13 67.92 70.67 49.58 49.48 50.53 68.90666667 49.86333333 2692 2616 2649 3190 2652.333333 1.04E-05 -0.278278468 00230///Purine metabolism+++00261///Monobactam biosynthesis+++00450///Selenocompound metabolism+++00920///Sulfur metabolism GO:0009336///sulfate adenylyltransferase complex (ATP) GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004020///adenylylsulfate kinase activity+++GO:0004781///sulfate adenylyltransferase (ATP) activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042803///protein homodimerization activity GO:0000103///sulfate assimilation+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0050428///3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 239719 239719 'Mrtfb' mRNA 1213.44 1201.95 1153.98 7.99 7.77 8.13 7.31 7.5 7.58 7.963333333 7.463333333 1276.03 1290.14 1224.39 1189.79 1263.52 0.442479379 0.07613312 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0005515///protein binding "GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001889///liver development+++GO:0003007///heart morphogenesis+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007517///muscle organ development+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0031175///neuron projection development+++GO:0045844///positive regulation of striated muscle tissue development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048514///blood vessel morphogenesis+++GO:0048568///embryonic organ development+++GO:0048738///cardiac muscle tissue development+++GO:0051145///smooth muscle cell differentiation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 23972 23972 'Papss2' mRNA 1847 1966 1880 27.86 29.17 30.07 15.52 15.88 15.59 29.03333333 15.66333333 1184 1184 1152 1897.666667 1173.333333 2.68E-20 -0.705604019 00230///Purine metabolism+++00261///Monobactam biosynthesis+++00450///Selenocompound metabolism+++00920///Sulfur metabolism GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004020///adenylylsulfate kinase activity+++GO:0004781///sulfate adenylyltransferase (ATP) activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0000103///sulfate assimilation+++GO:0007596///blood coagulation+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0050428///3'-phosphoadenosine 5'-phosphosulfate biosynthetic process+++GO:0060348///bone development 239731 239731 'Rimbp3' mRNA 12 11 3 0.11 0.1 0.03 0.22 0.15 0.13 0.08 0.166666667 28 19 16 8.666666667 21 0.086302876 1.277877233 GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0045202///synapse GO:0005515///protein binding+++GO:0030156///benzodiazepine receptor binding GO:0007274///neuromuscular synaptic transmission+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0030154///cell differentiation 239739 239739 'Lamp3' mRNA 0 2 1 0 0.03 0.02 0.03 0 0 0.016666667 0.01 2 0 0 1 0.666666667 0.867877377 -0.61693386 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097233///alveolar lamellar body membrane GO:0003674///molecular_function GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0010506///regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0035455///response to interferon-alpha+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0072594///establishment of protein localization to organelle+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1903900///regulation of viral life cycle 239743 239743 'Klhl6' mRNA 83 77 62 1.96 1.76 1.57 14.21 16.5 15.19 1.763333333 15.3 705 795 723 74 741 4.94E-100 3.31614413 GO:0002467///germinal center formation+++GO:0009617///response to bacterium+++GO:0050853///B cell receptor signaling pathway 239759 239759 'Liph' mRNA 2773 2964 2928.14 39.56 41.6 44.28 5.69 5.99 6.07 41.81333333 5.916666667 458 472 473 2888.38 467.6666667 4.19E-218 -2.639414231 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004465///lipoprotein lipase activity+++GO:0004620///phospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0008201///heparin binding+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process 239766 239766 'Rtp1' mRNA 211 212 193 3.7 3.66 3.59 0.23 0.17 0.17 3.65 0.19 15 11 11 205.3333333 12.33333333 3.25E-37 -4.06887254 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031849///olfactory receptor binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006612///protein targeting to membrane+++GO:0051205///protein insertion into membrane 239790 239790 'Ostn' mRNA 3 8 2 0.2 0.52 0.14 0 0 0.06 0.286666667 0.02 0 0 1 4.333333333 0.333333333 0.090233349 -3.586419868 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005102///signaling receptor binding+++GO:0005179///hormone activity GO:0001503///ossification+++GO:0003416///endochondral bone growth+++GO:0006486///protein glycosylation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0009755///hormone-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0030500///regulation of bone mineralization+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0046325///negative regulation of glucose import+++GO:1903860///negative regulation of dendrite extension 239796 239796 'Mb21d2' mRNA 552 559 526 9.82 9.85 9.93 7.69 7.1 7.58 9.866666667 7.456666667 497 448 473 545.6666667 472.6666667 0.075128647 -0.219092775 GO:0044877///protein-containing complex binding 23980 23980 'Pebp1' mRNA 19467 19688 18770 1014.56 1013.44 1037.9 1033.57 1046.3 1035.01 1021.966667 1038.293333 22758 22467 22035 19308.33333 22420 2.42E-05 0.203892614 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043679///axon terminus+++GO:0045177///apical part of cell GO:0000166///nucleotide binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0030414///peptidase inhibitor activity+++GO:0033612///receptor serine/threonine kinase binding+++GO:0051019///mitogen-activated protein kinase binding GO:0000165///MAPK cascade+++GO:0001505///regulation of neurotransmitter levels+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002026///regulation of the force of heart contraction+++GO:0006979///response to oxidative stress+++GO:0007286///spermatid development+++GO:0007568///aging+++GO:0009408///response to heat+++GO:0009611///response to wounding+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010243///response to organonitrogen compound+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0014070///response to organic cyclic compound+++GO:0014823///response to activity+++GO:0021766///hippocampus development+++GO:0042493///response to drug+++GO:0042755///eating behavior+++GO:0043409///negative regulation of MAPK cascade+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045471///response to ethanol+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0048240///sperm capacitation+++GO:0051412///response to corticosterone+++GO:0051591///response to cAMP+++GO:0051592///response to calcium ion+++GO:0051602///response to electrical stimulus+++GO:0060409///positive regulation of acetylcholine metabolic process 239827 239827 'Pigz' mRNA 279 337 318 7.04 8.39 8.36 10.19 8.91 10.04 7.93 9.713333333 463 392 440 311.3333333 431.6666667 0.001677126 0.457772299 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000026///alpha-1,2-mannosyltransferase activity+++GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006506///GPI anchor biosynthetic process+++GO:0097502///mannosylation 23983 23983 'Pcbp1' mRNA 4499 4611 2051 152.63 154.2 73.82 90.81 101.06 111.29 126.8833333 101.0533333 3076 3341 3648 3720.333333 3355 0.76691529 -0.142097717 03040///Spliceosome+++04216///Ferroptosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0008494///translation activator activity+++GO:0098847///sequence-specific single stranded DNA binding" GO:0006397///mRNA processing+++GO:0010468///regulation of gene expression+++GO:0039694///viral RNA genome replication+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051252///regulation of RNA metabolic process 239833 239833 'Lmln' mRNA 493 395 200 5.8 4.67 2.17 1.46 1.59 1.76 4.213333333 1.603333333 171 152 180 362.6666667 167.6666667 3.55E-06 -1.110231112 GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0016020///membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0051301///cell division 239839 239839 'Ccdc14' mRNA 115 111 119 1.6 1.59 1.66 0.85 0.89 1.24 1.616666667 0.993333333 74 73 99 115 82 0.07059047 -0.500990782 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0071539///protein localization to centrosome 23984 23984 'Pde10a' mRNA 1308.71 1364.33 936.27 5.48 5.67 4.19 2.06 1.62 2.03 5.113333333 1.903333333 586.18 447.35 557.73 1203.103333 530.42 2.32E-21 -1.188301327 00230///Purine metabolism+++04024///cAMP signaling pathway+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004118///cGMP-stimulated cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030552///cAMP binding+++GO:0030553///cGMP binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0008152///metabolic process+++GO:0010738///regulation of protein kinase A signaling+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0046069///cGMP catabolic process+++GO:0106070///regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 239845 239845 'Gpr156' mRNA 1332 1215 1179 17.03 16.43 16.26 2.37 2.17 1.92 16.57333333 2.153333333 196 169 164 1242 176.3333333 9.70E-136 -2.828333212 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004965///G protein-coupled GABA receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007214///gamma-aminobutyric acid signaling pathway 239849 239849 'Cd200r4' mRNA 2 0 4 0.07 0 0.14 4.26 5.42 3.91 0.07 4.53 151.33 191 140.5 2 160.9433333 7.36E-22 6.315408809 05167///Kaposi sarcoma-associated herpesvirus infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0150077///regulation of neuroinflammatory response 23985 23985 'Slc26a4' mRNA 3647 3930 3866 64.43 68.45 72.52 37.64 39.36 38.77 68.46666667 38.59 2420 2456 2406 3814.333333 2427.333333 3.92E-22 -0.664770972 04918///Thyroid hormone synthesis GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0070062///extracellular exosome GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015111///iodide transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity GO:0006885///regulation of pH+++GO:0008272///sulfate transport+++GO:0009887///animal organ morphogenesis+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0015705///iodide transport+++GO:0019532///oxalate transport+++GO:0032880///regulation of protein localization+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 239852 239852 'Zpld1' mRNA 656 715 685 11.8 12.77 13.61 12.6 12.88 13.2 12.72666667 12.89333333 817 812 795 685.3333333 808 0.034614478 0.22544575 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005201///extracellular matrix structural constituent GO:0008150///biological_process+++GO:0060005///vestibular reflex 239857 239857 'Cadm2' mRNA 37 33 36 0.2 0.18 0.21 0.09 0.07 0.04 0.196666667 0.066666667 20 14 8 35.33333333 14 0.012676959 -1.352841772 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005515///protein binding GO:0007155///cell adhesion 23986 23986 'Eci2' mRNA 1944.97 1943.1 1786.95 69.04 68.52 67.48 77.03 69.86 74.65 68.34666667 73.84666667 2479.08 2205.44 2317.91 1891.673333 2334.143333 2.77E-05 0.291924108 00071///Fatty acid degradation+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0043231///intracellular membrane-bounded organelle "GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity+++GO:0016853///isomerase activity+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds" GO:0006635///fatty acid beta-oxidation+++GO:0009062///fatty acid catabolic process 23988 23988 'Pin1' mRNA 1601 1758 1643 110.08 119.75 119.74 111.03 115.1 108.81 116.5233333 111.6466667 1846 1868 1747 1667.333333 1820.333333 0.187080427 0.115033827 04622///RIG-I-like receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030496///midbody+++GO:0036064///ciliary basal body+++GO:0043005///neuron projection+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0003774///motor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0016853///isomerase activity+++GO:0016859///cis-trans isomerase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0032794///GTPase activating protein binding+++GO:0050815///phosphoserine residue binding+++GO:0050816///phosphothreonine residue binding+++GO:0051219///phosphoprotein binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001666///response to hypoxia+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0030182///neuron differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032465///regulation of cytokinesis+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0042177///negative regulation of protein catabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0060393///regulation of pathway-restricted SMAD protein phosphorylation+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900180///regulation of protein localization to nucleus+++GO:1902430///negative regulation of amyloid-beta formation+++GO:2000146///negative regulation of cell motility 23989 23989 'Med24' mRNA 931 1025 953 14.96 16.19 16.23 12.51 12.57 13.32 15.79333333 12.8 895 878 923 969.6666667 898.6666667 0.251271731 -0.121259059 04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0044877///protein-containing complex binding+++GO:0046966///thyroid hormone receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006366///transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0016573///histone acetylation+++GO:0019827///stem cell population maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 23991 23991 'Cib1' mRNA 1291 1265 1235 79.24 76.99 80.7 102.62 108.64 102.26 78.97666667 104.5066667 1899 1965 1838 1263.666667 1900.666667 5.02E-14 0.577479766 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0032587///ruffle membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0031267///small GTPase binding+++GO:0043495///protein membrane anchor+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002931///response to ischemia+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007113///endomitotic cell cycle+++GO:0007155///cell adhesion+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010977///negative regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0030220///platelet formation+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0031122///cytoplasmic microtubule organization+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043086///negative regulation of catalytic activity+++GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051301///cell division+++GO:0051302///regulation of cell division+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071363///cellular response to growth factor stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000256///positive regulation of male germ cell proliferation 23992 23992 'Prkra' mRNA 616 645 581 21.25 21.76 21.23 18.33 17.66 17.58 21.41333333 17.85666667 605 565 558 614 576 0.418171977 -0.103235991 GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0070578///RISC-loading complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0070883///pre-miRNA binding GO:0006468///protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0034599///cellular response to oxidative stress+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0042473///outer ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0043583///ear development+++GO:0048705///skeletal system morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 239931 239931 'Cldn17' mRNA 1 0 0 0.05 0 0 0 0.05 0.14 0.016666667 0.063333333 0 1 3 0.333333333 1.333333333 0.608596619 1.894773281 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034707///chloride channel complex GO:0003674///molecular_function+++GO:0005198///structural molecule activity+++GO:0005254///chloride channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 23994 23994 'Dazap2' mRNA 6804 7116 6862 214.42 221.1 229.61 270.11 256.61 261.66 221.71 262.7933333 9853 9127 9233 6927.333333 9404.333333 3.73E-15 0.428175463 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0050699///WW domain binding GO:0071902///positive regulation of protein serine/threonine kinase activity 23996 23996 'Psmc4' mRNA 2197 2170 2228 91.02 88.69 97.93 110.92 121.97 118.29 92.54666667 117.06 3075 3299 3172 2198.333333 3182 1.26E-12 0.521205502 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0016234///inclusion body+++GO:0022624///proteasome accessory complex+++GO:0031597///cytosolic proteasome complex+++GO:0045202///synapse" GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0036402///proteasome-activating ATPase activity GO:0001824///blastocyst development+++GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:1901800///positive regulation of proteasomal protein catabolic process 23997 23997 'Psmd13' mRNA 1694 1794 1788 63.65 66.48 71.28 91.48 92.85 91.08 67.13666667 91.80333333 2797 2770 2694 1758.666667 2753.666667 1.21E-18 0.633936437 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex" GO:0004175///endopeptidase activity+++GO:0005198///structural molecule activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007127///meiosis I+++GO:0043248///proteasome assembly 239985 239985 'Arid1b' mRNA 978 1051 1017 7.16 7.54 7.76 4.53 4.13 4.79 7.486666667 4.483333333 717 648 743 1015.333333 702.6666667 3.58E-08 -0.5439126 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016514///SWI/SNF complex+++GO:0035060///brahma complex+++GO:0045202///synapse+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071565///nBAF complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007399///nervous system development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060996///dendritic spine development+++GO:0097026///dendritic cell dendrite assembly" 23999 23999 'Twf2' mRNA 3034 2962 2874 111.48 107.31 112.03 47.97 47.78 48.36 110.2733333 48.03666667 1500 1458 1463 2956.666667 1473.666667 8.44E-54 -1.016387674 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0030016///myofibril+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm "GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005080///protein kinase C binding+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0051015///actin filament binding" GO:0007275///multicellular organism development+++GO:0010591///regulation of lamellipodium assembly+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010976///positive regulation of neuron projection development+++GO:0030030///cell projection organization+++GO:0030042///actin filament depolymerization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032532///regulation of microvillus length+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0042989///sequestering of actin monomers+++GO:0045773///positive regulation of axon extension+++GO:0051016///barbed-end actin filament capping+++GO:0071300///cellular response to retinoic acid+++GO:0071363///cellular response to growth factor stimulus 24000 24000 'Ptpn21' mRNA 400 434 430 3.82 4.04 4.32 2.82 2.63 2.61 4.06 2.686666667 343 315 309 421.3333333 322.3333333 0.004234913 -0.399948893 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 24001 24001 'Tiam2' mRNA 599.34 682.25 652.24 6.44 7.41 6.92 3.1 2.62 2.46 6.923333333 2.726666667 355.88 289.68 270.63 644.61 305.3966667 1.42E-16 -1.095048636 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050772///positive regulation of axonogenesis+++GO:0090630///activation of GTPase activity 240023 240023 'Pnldc1' mRNA 16 17 18 0.32 0.36 0.4 0.38 0.27 0.27 0.36 0.306666667 17 14.73 14 17 15.24333333 0.815449164 -0.196025501 03018///RNA degradation GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0001825///blastocyst formation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 240025 240025 'Dact2' mRNA 132 109 32 2.6 2.13 0.67 1.11 2.03 1.85 1.8 1.663333333 64 116 105 91 95 0.878540591 0.077941346 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0051018///protein kinase A binding+++GO:0070097///delta-catenin binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003382///epithelial cell morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0030111///regulation of Wnt signaling pathway+++GO:0043588///skin development+++GO:0072061///inner medullary collecting duct development+++GO:1900108///negative regulation of nodal signaling pathway 240028 240028 'Lnpep' mRNA 308 268 232 4.13 3.35 3.4 4.01 3.94 4.36 3.626666667 4.103333333 390 365 379 269.3333333 378 0.001373541 0.480095322 04614///Renin-angiotensin system GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004177///aminopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0030163///protein catabolic process+++GO:0043171///peptide catabolic process+++GO:0060395///SMAD protein signal transduction+++GO:0120163///negative regulation of cold-induced thermogenesis 240034 240034 'Zfp760' mRNA 346 380 394 3.76 4.04 4.71 3.66 3.69 3.06 4.17 3.47 368 373 328 373.3333333 356.3333333 0.665933987 -0.081208918 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 240038 240038 'Zfp994' mRNA 187.59 183.11 155.78 2.43 2.36 2.14 2.15 2.16 2.23 2.31 2.18 187.76 181 190.29 175.4933333 186.35 0.750319743 0.078963588 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 24004 24004 'Rai2' mRNA 335 377 334 8.46 9.39 8.97 6.96 8.22 7.17 8.94 7.45 315 365 315 348.6666667 331.6666667 0.669394892 -0.081649328 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 240041 240041 'Zfp945' mRNA 431 435 410 3.55 3.49 3.55 2.73 2.55 2.32 3.53 2.533333333 386 352 317 425.3333333 351.6666667 0.043136416 -0.286535069 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 240047 240047 'Mmp25' mRNA 1 2 10 0.02 0.03 0.16 0.36 0.11 0.23 0.07 0.233333333 29 8 17 4.333333333 18 0.03943572 1.998651009 "04928///Parathyroid hormone synthesis, secretion and action" GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016504///peptidase activator activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010952///positive regulation of peptidase activity+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0060022///hard palate development 240055 240055 'Neurl1b' mRNA 41 45 36 0.35 0.37 0.32 0.38 0.21 0.27 0.346666667 0.286666667 52 28 36 40.66666667 38.66666667 0.867000631 -0.086138458 GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination+++GO:0070086///ubiquitin-dependent endocytosis 240057 240057 'Syngap1' mRNA 192 195 104 1.74 1.61 0.94 0.64 0.55 0.75 1.43 0.646666667 88 74 94 163.6666667 85.33333333 4.39E-04 -0.940160909 04014///Ras signaling pathway "GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007389///pattern specification process+++GO:0008542///visual learning+++GO:0016358///dendrite development+++GO:0043087///regulation of GTPase activity+++GO:0043113///receptor clustering+++GO:0043408///regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048167///regulation of synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0050771///negative regulation of axonogenesis+++GO:0050803///regulation of synapse structure or activity+++GO:0098880///maintenance of postsynaptic specialization structure 240058 240058 'Cpne5' mRNA 23 45 25 0.58 0.97 0.67 0.36 0.47 0.17 0.74 0.333333333 17 23 9 31 16.33333333 0.126645101 -0.926736003 GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0030154///cell differentiation+++GO:0071277///cellular response to calcium ion+++GO:1903861///positive regulation of dendrite extension 240063 240063 'Zfp811' mRNA 95.44 58 78 1.44 0.83 1.26 0.42 0.45 0.6 1.176666667 0.49 32 34 44 77.14666667 36.66666667 0.00276228 -1.08375434 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 240064 240064 'Zfp799' mRNA 827.17 781.84 806.71 7.72 7.24 7.57 4.22 3.89 5.02 7.51 4.376666667 554.83 529.42 588.23 805.24 557.4933333 3.54E-07 -0.543519188 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 240066 240066 'Zfp870' mRNA 347 360 380 3.46 3.55 4.04 2.97 2.79 2.8 3.683333333 2.853333333 340 315 312 362.3333333 322.3333333 0.256845836 -0.183217937 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 240067 240067 'Zfp952' mRNA 530 523 473 9.62 9.35 9.12 6.4 6.51 6.61 9.363333333 6.506666667 405 409 411 508.6666667 408.3333333 0.008360462 -0.326969654 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 240068 240068 'Zfp563' mRNA 527.98 532.19 467.39 1.94 2.09 1.89 1.35 1.29 1.11 1.973333333 1.25 370.61 364.35 338.38 509.1866667 357.78 3.00E-05 -0.519364204 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 240069 240069 'Morc2b' mRNA 2 0 4 0.02 0 0.06 0.04 0.04 0.01 0.026666667 0.03 3 3 1 2 2.333333333 0.939175627 0.176027341 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007129///synapsis+++GO:0007276///gamete generation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:1990918///double-strand break repair involved in meiotic recombination" 240084 240084 'Cchcr1' mRNA 230 232 244 4.67 4.61 5.23 4.41 3.87 3.72 4.836666667 4 248 215 202 235.3333333 221.6666667 0.650223068 -0.101140608 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006611///protein export from nucleus+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation 240087 240087 'Mdc1' mRNA 505.67 560.76 398.07 3.75 4.09 3.13 4.09 2.96 3.27 3.656666667 3.44 635.77 454.14 490.63 488.1666667 526.8466667 0.583890971 0.1011847 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005925///focal adhesion+++GO:0016604///nuclear body GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070975///FHA domain binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle 240095 240095 'H2-M5' mRNA 0 0 2 0 0 0.05 0.02 0.05 0 0.016666667 0.023333333 1 1 0 0.666666667 0.666666667 0.992437553 -0.07674363 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0032398///MHC class Ib protein complex+++GO:0033106///cis-Golgi network membrane+++GO:0042612///MHC class I protein complex GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042288///MHC class I protein binding+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042610///CD8 receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0046978///TAP1 binding+++GO:0046979///TAP2 binding+++GO:0071889///14-3-3 protein binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 24010 24010 'Ik' mRNA 2374 2329 2406 67.73 65.46 72.82 65.54 67.31 69.66 68.67 67.50333333 2641 2648 2717 2369.666667 2668.666667 0.03966722 0.158459094 GO:0000228///nuclear chromosome+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0097431///mitotic spindle pole GO:0042802///identical protein binding "GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0008380///RNA splicing+++GO:0034501///protein localization to kinetochore" 240119 240119 'St6gal2' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00510///N-Glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003824///catalytic activity+++GO:0003835///beta-galactoside alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0005975///carbohydrate metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0006486///protein glycosylation+++GO:0009311///oligosaccharide metabolic process+++GO:0097503///sialylation 24012 24012 'Rgs7' mRNA 1 2 1 0.03 0.05 0.03 0 0 0 0.036666667 0 0 0 0 1.333333333 0 0.437121753 -2.859116386 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0044292///dendrite terminus+++GO:0045121///membrane raft+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031681///G-protein beta-subunit binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0060078///regulation of postsynaptic membrane potential+++GO:1901381///positive regulation of potassium ion transmembrane transport 240120 240120 'Zfp119b' mRNA 264.38 262.5 307.58 7.2 7.3 9.54 5.92 6.5 5.13 8.013333333 5.85 242.4 256.54 205.86 278.1533333 234.9333333 0.181030671 -0.260571558 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 240121 240121 'Fsd1' mRNA 55 60 63 1.82 1.96 2.21 1.01 1.09 1.34 1.996666667 1.146666667 35 37 45 59.33333333 39 0.10458399 -0.618615376 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0032154///cleavage furrow GO:0008017///microtubule binding+++GO:0042802///identical protein binding GO:0007049///cell cycle+++GO:0031122///cytoplasmic microtubule organization+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division+++GO:0051302///regulation of cell division+++GO:0060236///regulation of mitotic spindle organization 24013 24013 'Grk1' mRNA 94.82 80.94 69.34 0.67 0.56 0.52 0.1 0.11 0.14 0.583333333 0.116666667 16.34 18.05 21.25 81.7 18.54666667 8.71E-09 -2.150568976 04062///Chemokine signaling pathway+++04144///Endocytosis+++04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0050254///rhodopsin kinase activity GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0008594///photoreceptor cell morphogenesis+++GO:0009416///response to light stimulus+++GO:0009966///regulation of signal transduction+++GO:0016310///phosphorylation+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0042327///positive regulation of phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0050896///response to stimulus+++GO:0060060///post-embryonic retina morphogenesis in camera-type eye 240131 240131 'Lrrc30' mRNA 109 90 85 3.58 2.91 2.96 0.23 0.21 0.21 3.15 0.216666667 8 7 7 94.66666667 7.333333333 4.20E-17 -3.700509657 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0004722///protein serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction 24014 24014 'Rnasel' mRNA 40 44.98 33 0.5 0.56 0.44 4.98 5.11 5.43 0.5 5.173333333 412.12 419.31 421.48 39.32666667 417.6366667 3.96E-65 3.410937101 04621///NOD-like receptor signaling pathway+++05160///Hepatitis C+++05164///Influenza A+++05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0043488///regulation of mRNA stability+++GO:0045071///negative regulation of viral genome replication+++GO:0045444///fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0051607///defense response to virus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 24015 24015 'Abce1' mRNA 1038 1098 1109 14.73 15.33 16.7 20.96 20.35 20.61 15.58666667 20.64 1700 1612 1619 1081.666667 1643.666667 1.05E-12 0.590170183 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0005506///iron ion binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0043024///ribosomal small subunit binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0060698///endoribonuclease inhibitor activity" GO:0000054///ribosomal subunit export from nucleus+++GO:0006413///translational initiation+++GO:0006415///translational termination+++GO:0006417///regulation of translation+++GO:0060702///negative regulation of endoribonuclease activity 240168 240168 'Rasgrp3' mRNA 333 340 340 3.87 3.86 4.19 7.15 6.79 7.44 3.973333333 7.126666667 707 659 709 337.6666667 691.6666667 4.61E-19 1.02177194 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04662///B cell receptor signaling pathway+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding+++GO:0019900///kinase binding+++GO:0031267///small GTPase binding GO:0007264///small GTPase mediated signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity 24017 24017 'Rnf13' mRNA 4433 4551 4465 157.72 162.21 168.78 150.65 167.94 156.83 162.9033333 158.4733333 4631 5002 4577 4483 4736.666667 0.40275056 0.067726846 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0008432///JUN kinase binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070304///positive regulation of stress-activated protein kinase signaling cascade 240174 240174 'Thada' mRNA 890 844.77 806 4.72 4.48 4.36 3.23 2.92 3.22 4.52 3.123333333 701 611.02 653.93 846.9233333 655.3166667 1.58E-04 -0.382308943 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0003674///molecular_function GO:0030488///tRNA methylation+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0055088///lipid homeostasis 24018 24018 'Rngtt' mRNA 637.76 722.22 681.14 6.82 7.37 7.71 7.58 7.99 8.6 7.3 8.056666667 731.75 706.91 749.93 680.3733333 729.53 0.498632657 0.087539581 03015///mRNA surveillance pathway GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004484///mRNA guanylyltransferase activity+++GO:0004651///polynucleotide 5'-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008192///RNA guanylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0050355///triphosphatase activity GO:0006370///7-methylguanosine mRNA capping+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006470///protein dephosphorylation+++GO:0008152///metabolic process+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0098507///polynucleotide 5' dephosphorylation 240185 240185 'Jcad' mRNA 1870 2151 1772 14.69 16.6 14.76 12.94 13.67 12.66 15.35 13.09 1899 1960 1798 1931 1885.666667 0.686252067 -0.043177618 GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0043410///positive regulation of MAPK cascade+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1903672///positive regulation of sprouting angiogenesis 240186 240186 'Zfp438' mRNA 267 276 208 4.55 4.64 3.78 2.78 1.88 2.25 4.323333333 2.303333333 188 125 144 250.3333333 152.3333333 2.75E-04 -0.726495066 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 240215 240215 'Slc4a9' mRNA 0 0 1 0 0 0.02 0.02 0 0 0.006666667 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0045177///apical part of cell GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport 240216 240216 'E230025N22Rik' mRNA 2485 2626 2602 73.87 76.96 82.35 5.84 6.57 6.38 77.72666667 6.263333333 224 252 239 2571 238.3333333 1.02E-280 -3.44365149 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 240239 240239 'Gpr151' mRNA 6 1 2 0.2 0.03 0.07 0.48 0.29 0.47 0.1 0.413333333 17 10 16 3 14.33333333 0.022862717 2.244753755 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010447///response to acidic pH 240255 240255 'Ythdc2' mRNA 167 147 152 1.43 1.23 1.47 1.07 1.05 1 1.376666667 1.04 143 134 127 155.3333333 134.6666667 0.364600645 -0.21856764 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0035770///ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0034458///3'-5' RNA helicase activity+++GO:0070063///RNA polymerase binding+++GO:1990247///N6-methyladenosine-containing RNA binding "GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0034612///response to tumor necrosis factor+++GO:0044829///positive regulation by host of viral genome replication+++GO:0048477///oogenesis+++GO:0048599///oocyte development+++GO:0051321///meiotic cell cycle+++GO:0051729///germline cell cycle switching, mitotic to meiotic cell cycle+++GO:0070555///response to interleukin-1" 240261 240261 'Ccdc112' mRNA 50 60 47 0.99 1.18 1.01 0.6 0.79 0.74 1.06 0.71 35 45 42 52.33333333 40.66666667 0.380946423 -0.370550748 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 240263 240263 'Fem1c' mRNA 270 242 172 5.19 4.58 3.51 3.59 4.74 3.75 4.426666667 4.026666667 215 277 217 228 236.3333333 0.863090843 0.049333097 GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 240283 240283 'Dmxl1' mRNA 569 483 484 2.55 2.11 2.27 2.46 1.93 2.24 2.31 2.21 643 500 571 512 571.3333333 0.327223746 0.145053319 04142///Lysosome GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043291///RAVE complex GO:0003674///molecular_function GO:0007035///vacuolar acidification 24030 24030 'Mrps12' mRNA 1011 987 998 98.03 93.52 100.92 106.98 132.89 122.1 97.49 120.6566667 1293 1521 1407 998.6666667 1407 6.33E-07 0.48359028 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 240322 240322 'Adamts19' mRNA 260 263 155.05 2.8 2.68 1.73 0.32 0.38 0.31 2.403333333 0.336666667 34.05 35.51 32.99 226.0166667 34.18333333 6.28E-25 -2.748115629 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0030198///extracellular matrix organization 240327 240327 'Gm4951' mRNA 285.13 302.98 286.02 4.81 5.02 5.29 7.54 8.49 8.18 5.04 8.07 503 558 533 291.3766667 531.3333333 3.27E-11 0.858032217 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 240328 240328 'F830016B08Rik' mRNA 4836.97 4812.29 4427.72 39.41 38.54 38.26 21.72 19.2 21.43 38.73666667 20.78333333 3070.23 2651.53 2934.05 4692.326667 2885.27 9.09E-31 -0.713218367 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 240332 240332 'Slc6a7' mRNA 66 90 64 0.74 1.04 0.78 0.42 0.3 0.44 0.853333333 0.386666667 39 25 39 73.33333333 34.33333333 0.002285707 -1.104515822 04721///Synaptic vesicle cycle GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0015193///L-proline transmembrane transporter activity+++GO:0015293///symporter activity GO:0006836///neurotransmitter transport+++GO:0006865///amino acid transport+++GO:0015824///proline transport+++GO:0035524///proline transmembrane transport+++GO:0035725///sodium ion transmembrane transport 240334 240334 'Pcyox1l' mRNA 620 592 634 17 15.92 18.52 9.99 9.9 10.59 17.14666667 10.16 423 405 429 615.3333333 419 1.96E-06 -0.568202051 GO:0005576///extracellular region "GO:0001735///prenylcysteine oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016670///oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor" GO:0030327///prenylated protein catabolic process+++GO:0030328///prenylcysteine catabolic process 240354 240354 'Malt1' mRNA 264.4 297.13 229.5 2.87 4.11 3.15 4 4.53 3.8 3.376666667 4.11 382.65 396.61 388.4 263.6766667 389.22 1.48E-04 0.554016755 04064///NF-kappa B signaling pathway+++04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++05131///Shigellosis+++05152///Tuberculosis GO:0001650///fibrillar center+++GO:0002096///polkadots+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032449///CBM complex+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0019209///kinase activator activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association GO:0001923///B-1 B cell differentiation+++GO:0002376///immune system process+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0009620///response to fungus+++GO:0016567///protein ubiquitination+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042098///T cell proliferation+++GO:0042113///B cell activation+++GO:0042981///regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0050852///T cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050870///positive regulation of T cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051168///nuclear export+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:2000321///positive regulation of T-helper 17 cell differentiation 240396 240396 'Mex3c' mRNA 346.83 403.25 243.24 3.98 4.55 2.91 3.93 3.23 3.88 3.813333333 3.68 393.26 315.1 367 331.1066667 358.4533333 0.606135662 0.111356661 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0003415///chondrocyte hypertrophy+++GO:0016567///protein ubiquitination+++GO:0045598///regulation of fat cell differentiation+++GO:0097009///energy homeostasis 240411 240411 'Loxhd1' mRNA 2778 2704 2602 19.08 18.23 18.85 1.86 1.89 1.94 18.72 1.896666667 311 309 315 2694.666667 311.6666667 2.87E-301 -3.123541089 GO:0032420///stereocilium+++GO:0042995///cell projection GO:0004096///catalase activity+++GO:0020037///heme binding GO:0007605///sensory perception of sound 240427 240427 'Setbp1' mRNA 676 691 531 3.21 3.22 2.67 1.17 1.22 1.17 3.033333333 1.186666667 285 290 274 632.6666667 283 4.27E-20 -1.167426811 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 24044 24044 'Scamp2' mRNA 2039 2069 1918 48.78 48.72 48.65 77.41 74.57 76.2 48.71666667 76.06 3722 3500 3546 2008.666667 3589.333333 3.53E-43 0.826123021 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane GO:0015031///protein transport 240442 240442 'Adnp2' mRNA 319 305 247 3.5 3.32 2.91 2.8 3.19 2.7 3.243333333 2.896666667 309 329 281 290.3333333 306.3333333 0.741096307 0.070021933 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0010468///regulation of gene expression+++GO:0030182///neuron differentiation+++GO:0030307///positive regulation of cell growth+++GO:0034599///cellular response to oxidative stress+++GO:0060548///negative regulation of cell death+++GO:0071300///cellular response to retinoic acid 240444 240444 'Kcng2' mRNA 7 8 8 0.15 0.16 0.18 0.07 0 0.04 0.163333333 0.036666667 4 0 2 7.666666667 2 0.142222287 -1.963703945 GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 24045 24045 'Scamp3' mRNA 1445.34 1482.62 1369.61 53.75 54.37 54.04 76.1 80.53 75.08 54.05333333 77.23666667 2349.39 2425.85 2243.34 1432.523333 2339.526667 2.48E-22 0.697250399 GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032588///trans-Golgi network membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane GO:0031625///ubiquitin protein ligase binding GO:0006886///intracellular protein transport+++GO:0010033///response to organic substance+++GO:0015031///protein transport+++GO:0032526///response to retinoic acid 24046 24046 'Scn11a' mRNA 0 2 1 0 0.02 0.01 0.01 0 0.01 0.01 0.006666667 1 0 1 1 0.666666667 0.863090843 -0.601024929 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0044299///C-fiber+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0019228///neuronal action potential+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051930///regulation of sensory perception of pain+++GO:0055085///transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098655///cation transmembrane transport 24047 24047 'Ccl19' mRNA 55.74 58.48 47.57 7.74 8.09 7.01 4.25 4.78 4 7.613333333 4.343333333 34.91 38.12 31.67 53.93 34.9 0.106416943 -0.643259015 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031732///CCR7 chemokine receptor binding+++GO:0031735///CCR10 chemokine receptor binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0001768///establishment of T cell polarity+++GO:0001771///immunological synapse formation+++GO:0002407///dendritic cell chemotaxis+++GO:0002408///myeloid dendritic cell chemotaxis+++GO:0002548///monocyte chemotaxis+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0010560///positive regulation of glycoprotein biosynthetic process+++GO:0030593///neutrophil chemotaxis+++GO:0031295///T cell costimulation+++GO:0031640///killing of cells of other organism+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034695///response to prostaglandin E+++GO:0042102///positive regulation of T cell proliferation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0045807///positive regulation of endocytosis+++GO:0045860///positive regulation of protein kinase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0048247///lymphocyte chemotaxis+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048469///cell maturation+++GO:0050921///positive regulation of chemotaxis+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0060491///regulation of cell projection assembly+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071731///response to nitric oxide+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0097029///mature conventional dendritic cell differentiation+++GO:0098586///cellular response to virus+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000147///positive regulation of cell motility+++GO:2000549///positive regulation of dendritic cell dendrite assembly+++GO:2000669///negative regulation of dendritic cell apoptotic process 240476 240476 'Zfp407' mRNA 534.16 568 515.7 2.03 2.26 2.22 1.99 1.63 1.89 2.17 1.836666667 536.15 422 484.16 539.2866667 480.77 0.194093587 -0.177819418 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 240479 240479 'Dipk1c' mRNA 274 255 167 3.76 3.48 2.11 0.65 0.65 0.7 3.116666667 0.666666667 46 57 52 232 51.66666667 4.56E-19 -2.168324503 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 24050 24050 'Septin3' mRNA 645 651 628 5.57 5.74 5.75 2.13 1.89 1.81 5.686666667 1.943333333 271 237 215 641.3333333 241 4.42E-29 -1.425009875 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0031105///septin complex+++GO:0032153///cell division site+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0099569///presynaptic cytoskeleton GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0034613///cellular protein localization+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis 240505 240505 'Cdc42bpg' mRNA 111 99 104 0.98 0.86 1.01 0.86 0.69 0.82 0.95 0.79 112 84 104 104.6666667 100 0.819224656 -0.080181567 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031252///cell leading edge+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031032///actomyosin structure organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction 24051 24051 'Sgcb' mRNA 870 964 912 12.63 13.76 14.04 16.34 15.89 13.95 13.47666667 15.39333333 1296 1231 1071 915.3333333 1199.333333 1.70E-04 0.37710988 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016011///dystroglycan complex+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0005515///protein binding GO:0007517///muscle organ development+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0055013///cardiac muscle cell development+++GO:0061024///membrane organization+++GO:0097084///vascular smooth muscle cell development 240514 240514 'Ccdc85b' mRNA 954 963.76 944.98 11.66 11.58 12.25 10.71 10.91 11.45 11.83 11.02333333 1008.96 1004.63 1045.27 954.2466667 1019.62 0.438166653 0.083697062 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0070097///delta-catenin binding "GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0040008///regulation of growth+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 240518 240518 'Peli3' mRNA 569 558 544 9.5 9.99 9.72 2.96 2.87 2.7 9.736666667 2.843333333 186 202 184 557 190.6666667 2.54E-31 -1.557893439 GO:0005575///cellular_component GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0008063///Toll signaling pathway+++GO:0008592///regulation of Toll signaling pathway+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016567///protein ubiquitination+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032480///negative regulation of type I interferon production+++GO:0045751///negative regulation of Toll signaling pathway+++GO:0050829///defense response to Gram-negative bacterium+++GO:0070428///regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0070534///protein K63-linked ubiquitination+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 24052 24052 'Sgcd' mRNA 219 215 219 1.15 1.1 1.3 0.46 0.42 0.5 1.183333333 0.46 95 90 106 217.6666667 97 3.68E-09 -1.178824321 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016011///dystroglycan complex+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0042383///sarcolemma GO:0005515///protein binding GO:0003015///heart process+++GO:0019722///calcium-mediated signaling+++GO:0031503///protein-containing complex localization+++GO:0034629///cellular protein-containing complex localization+++GO:0048738///cardiac muscle tissue development+++GO:0048739///cardiac muscle fiber development+++GO:0055013///cardiac muscle cell development+++GO:0055074///calcium ion homeostasis+++GO:0060047///heart contraction+++GO:0060048///cardiac muscle contraction+++GO:0060977///coronary vasculature morphogenesis+++GO:0061024///membrane organization+++GO:0086003///cardiac muscle cell contraction 24053 24053 'Sgcg' mRNA 0 6 4 0 0.09 0.07 0.03 0.01 0 0.053333333 0.013333333 2 1 0 3.333333333 1 0.437864513 -1.759692736 05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05416///Viral myocarditis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016011///dystroglycan complex+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0005515///protein binding GO:0048738///cardiac muscle tissue development+++GO:0060047///heart contraction+++GO:0061024///membrane organization 240549 240549 'Gm4952' mRNA 2 0 0 0.08 0 0 0.03 0 0 0.026666667 0.01 1 0 0 0.666666667 0.333333333 0.863090843 -0.883128046 00360///Phenylalanine metabolism GO:0005739///mitochondrion "GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047961///glycine N-acyltransferase activity+++GO:0047962///glycine N-benzoyltransferase activity" GO:0006544///glycine metabolic process 24055 24055 'Sh3bp2' mRNA 132 124 95 2.45 2.21 1.85 16.94 16.53 15.97 2.17 16.48 1065 1013 972 117 1016.666667 2.81E-127 3.110552921 04650///Natural killer cell mediated cytotoxicity GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0007165///signal transduction 24056 24056 'Sh3bp5' mRNA 1886.47 2066.14 1925.8 30.66 32.69 33.22 22.07 20.73 21.57 32.19 21.45666667 1555.08 1432.42 1481.64 1959.47 1489.713333 6.34E-08 -0.407710384 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0004860///protein kinase inhibitor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017124///SH3 domain binding GO:0006469///negative regulation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0061099///negative regulation of protein tyrosine kinase activity 24057 24057 'Sh3yl1' mRNA 372 444 362 12.32 14.49 12.72 5.16 6.05 5.84 13.17666667 5.683333333 179 205 196 392.6666667 193.3333333 2.34E-11 -1.030436546 GO:0032587///ruffle membrane GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0035091///phosphatidylinositol binding GO:0006661///phosphatidylinositol biosynthetic process+++GO:1900027///regulation of ruffle assembly 24058 24058 'Sigirr' mRNA 272 263 293 9.77 9.7 11.15 9.77 10.95 8.91 10.20666667 9.876666667 295 347 281 276 307.6666667 0.468356604 0.143464596 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003953///NAD+ nucleosidase activity GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0006953///acute-phase response+++GO:0007165///signal transduction+++GO:0032682///negative regulation of chemokine production+++GO:0043433///negative regulation of DNA-binding transcription factor activity 24059 24059 'Slco2a1' mRNA 617 745 763 7.44 8.84 9.76 10.98 9.73 9.86 8.68 10.19 1048 907 911 708.3333333 955.3333333 4.68E-04 0.41560181 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015132///prostaglandin transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015732///prostaglandin transport+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport 24060 24060 'Slc35a1' mRNA 1071.93 1176.92 1097.12 28.97 31.22 31.65 38.07 33.46 36.59 30.61333333 36.04 1606.14 1370 1497.12 1115.323333 1491.086667 2.78E-06 0.406767499 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0005456///CMP-N-acetylneuraminate transmembrane transporter activity+++GO:0005459///UDP-galactose transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008643///carbohydrate transport+++GO:0015782///CMP-N-acetylneuraminate transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport 24061 24061 'Smc1a' mRNA 1898 1951 1768 27.34 26.29 26.15 27.06 26.26 26.3 26.59333333 26.54 2227 2101 2125 1872.333333 2151 0.006961872 0.18924366 04110///Cell cycle+++04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0016363///nuclear matrix+++GO:0030893///meiotic cohesin complex+++GO:0097431///mitotic spindle pole" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0036033///mediator complex binding+++GO:0046982///protein heterodimerization activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0009314///response to radiation+++GO:0019827///stem cell population maintenance+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0090307///mitotic spindle assembly 240613 240613 '9930021J03Rik' mRNA 921.95 923.38 877.1 3.12 3.12 3.25 2.32 2.17 2.17 3.163333333 2.22 790.77 682.58 718.26 907.4766667 730.5366667 9.53E-04 -0.325678848 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 240614 240614 'Ranbp6' mRNA 570 603 682 6.26 6.52 7.95 5.34 4.83 5.42 6.91 5.196666667 559 494 550 618.3333333 534.3333333 0.100790959 -0.227374494 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008139///nuclear localization sequence binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0015031///protein transport 24063 24063 'Spry1' mRNA 283 278 254 7.25 6.97 6.95 4.88 4.9 5.33 7.056666667 5.036666667 218 215 231 271.6666667 221.3333333 0.072370044 -0.305872437 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding GO:0000132///establishment of mitotic spindle orientation+++GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001759///organ induction+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0009966///regulation of signal transduction+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048513///animal organ development+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0060449///bud elongation involved in lung branching+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902747///negative regulation of lens fiber cell differentiation 240638 240638 'Slc16a12' mRNA 5 11 12 0.07 0.14 0.18 0.07 0.09 0.03 0.13 0.063333333 6 7 2 9.333333333 5 0.413746963 -0.920446481 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005308///creatine transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0015881///creatine transmembrane transport+++GO:0055085///transmembrane transport 24064 24064 'Spry2' mRNA 778 700 859 20.86 18.38 24.43 20.62 19.26 20.84 21.22333333 20.24 886 805 866 779 852.3333333 0.419352004 0.112694383 04013///MAPK signaling pathway - fly+++05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:1990752///microtubule end GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0000132///establishment of mitotic spindle orientation+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0009966///regulation of signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0016525///negative regulation of angiogenesis+++GO:0030324///lung development+++GO:0030335///positive regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031345///negative regulation of cell projection organization+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042472///inner ear morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045165///cell fate commitment+++GO:0045595///regulation of cell differentiation+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048513///animal organ development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060425///lung morphogenesis+++GO:0060437///lung growth+++GO:0060449///bud elongation involved in lung branching+++GO:0060541///respiratory system development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1902747///negative regulation of lens fiber cell differentiation+++GO:1990830///cellular response to leukemia inhibitory factor 240641 240641 'Kif20b' mRNA 63 56 56 0.61 0.53 0.58 2.42 1.83 2.7 0.573333333 2.316666667 287 210 307 58.33333333 268 8.40E-23 2.18670042 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0042995///cell projection+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0051233///spindle midzone+++GO:0070938///contractile ring+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0042803///protein homodimerization activity+++GO:0050699///WW domain binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0001843///neural tube closure+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division+++GO:0008284///positive regulation of cell proliferation+++GO:0032467///positive regulation of cytokinesis+++GO:0035372///protein localization to microtubule+++GO:0048812///neuron projection morphogenesis+++GO:0051301///cell division+++GO:0070201///regulation of establishment of protein localization+++GO:0090316///positive regulation of intracellular protein transport+++GO:1903438///positive regulation of mitotic cytokinetic process+++GO:2000114///regulation of establishment of cell polarity+++GO:2001222///regulation of neuron migration+++GO:2001224///positive regulation of neuron migration 24066 24066 'Spry4' mRNA 135 150 197 1.44 1.67 2.35 2.29 1.39 1.85 1.82 1.843333333 231 138 188 160.6666667 185.6666667 0.532728002 0.184541325 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048513///animal organ development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1990830///cellular response to leukemia inhibitory factor 240660 240660 'Slc35g1' mRNA 51.87 65.01 45.13 0.81 1 0.75 2.05 2.06 2.1 0.853333333 2.07 150.58 148.03 148.96 54.00333333 149.19 6.65E-09 1.462617715 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0051480///regulation of cytosolic calcium ion concentration+++GO:1990034///calcium ion export across plasma membrane 240665 240665 'Ccnj' mRNA 160 165 127 2.31 2.34 1.94 1.47 1.35 1.52 2.196666667 1.446666667 118 107 116 150.6666667 113.6666667 0.074165949 -0.414437415 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0044772///mitotic cell cycle phase transition 240667 240667 'Sec31b' mRNA 62 74 83 0.85 1 1.21 0.43 0.5 0.41 1.02 0.446666667 36 41 33 73 36.66666667 0.004213043 -1.009129216 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030120///vesicle coat+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0070971///endoplasmic reticulum exit site GO:0005198///structural molecule activity GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0090110///cargo loading into COPII-coated vesicle 24067 24067 'Srp54a' mRNA 362.52 425.03 310.59 4.94 5.7 4.53 3.5 3.12 4.62 5.056666667 3.746666667 289.76 262.34 376.41 366.0466667 309.5033333 0.184101059 -0.249570367 03060///Protein export "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0048500///signal recognition particle" GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008312///7S RNA binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0030942///endoplasmic reticulum signal peptide binding+++GO:0043021///ribonucleoprotein complex binding "GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0030593///neutrophil chemotaxis+++GO:0030851///granulocyte differentiation+++GO:0031017///exocrine pancreas development" 240672 240672 'Dusp5' mRNA 85 104 16 2.7 3.25 0.54 2.37 2.86 3.68 2.163333333 2.97 86 101 129 68.33333333 105.3333333 0.469161897 0.645288483 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding "GO:0000188///inactivation of MAPK activity+++GO:0001706///endoderm formation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045906///negative regulation of vasoconstriction" 240675 240675 'Vwa2' mRNA 13 13 13 0.2 0.2 0.19 0.17 0 0.16 0.196666667 0.11 14 0 13 13 9 0.629589418 -0.554216403 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0042802///identical protein binding GO:0007161///calcium-independent cell-matrix adhesion+++GO:0046626///regulation of insulin receptor signaling pathway 24068 24068 'Sra1' mRNA 1250 1301 1219 83.17 85.63 86.18 101.53 108.68 99.94 84.99333333 103.3833333 1750 1825 1664 1256.666667 1746.333333 5.38E-09 0.463753127 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005831///steroid hormone aporeceptor complex+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0031209///SCAR complex+++GO:0031252///cell leading edge+++GO:0045171///intercellular bridge+++GO:1990904///ribonucleoprotein complex GO:0002153///steroid receptor RNA activator RNA binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007346///regulation of mitotic cell cycle+++GO:0030154///cell differentiation+++GO:0042981///regulation of apoptotic process+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071391///cellular response to estrogen stimulus 24069 24069 'Sufu' mRNA 861 750 721 10.21 8.75 9.07 7.56 8.56 7.63 9.343333333 7.916666667 734 811 717 777.3333333 754 0.718455535 -0.053588516 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++05200///Pathways in cancer+++05217///Basal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0003281///ventricular septum development+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021775///smoothened signaling pathway involved in ventral spinal cord interneuron specification+++GO:0021776///smoothened signaling pathway involved in spinal cord motor neuron cell fate specification+++GO:0035904///aorta development+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0043588///skin development+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0060976///coronary vasculature development+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 240690 240690 'St18' mRNA 1 0 0 0.01 0 0 0.12 0.14 0.07 0.003333333 0.11 16 18 8 0.333333333 14 6.18E-04 5.276524815 GO:0005634///nucleus+++GO:0032993///protein-DNA complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" 240697 240697 'Mcmdc2' mRNA 157.29 121.44 95.99 3.43 2.6 2.22 1.5 1.12 1.54 2.75 1.386666667 79.04 57.9 78.67 124.9066667 71.87 0.004280243 -0.808902851 GO:0005634///nucleus+++GO:0042555///MCM complex GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding GO:0000727///double-strand break repair via break-induced replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007130///synaptonemal complex assembly+++GO:0007146///meiotic recombination nodule assembly+++GO:0007283///spermatogenesis+++GO:0032508///DNA duplex unwinding+++GO:0042140///late meiotic recombination nodule assembly+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:1902975///mitotic DNA replication initiation+++GO:1990918///double-strand break repair involved in meiotic recombination 24070 24070 'Mpdu1' mRNA 1481 1513 1417 67.12 67.71 68.17 77.01 82.48 79.94 67.66666667 79.81 1949 2042 1955 1470.333333 1982 1.51E-08 0.420135312 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process 24071 24071 'Synj2bp' mRNA 1905.13 1835.81 1920.35 14.29 14.69 14.62 12.37 14.06 14.02 14.53333333 13.48333333 2020.69 1847.17 1922.02 1887.096667 1929.96 0.863090843 0.018533265 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0009986///cell surface+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0070699///type II activin receptor binding GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002090///regulation of receptor internalization+++GO:0002092///positive regulation of receptor internalization+++GO:0006605///protein targeting+++GO:0006897///endocytosis+++GO:0007028///cytoplasm organization+++GO:0007266///Rho protein signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0008593///regulation of Notch signaling pathway+++GO:0009790///embryo development+++GO:0010596///negative regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030100///regulation of endocytosis+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0043113///receptor clustering+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0048312///intracellular distribution of mitochondria+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:2000010///positive regulation of protein localization to cell surface 240725 240725 'Sulf1' mRNA 3200 3234 3165 34.85 34.53 36.5 28.37 27.56 26.53 35.29333333 27.48666667 2976 2812 2708 3199.666667 2832 0.005566311 -0.188818577 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0045121///membrane raft GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0005509///calcium ion binding+++GO:0005539///glycosaminoglycan binding+++GO:0008449///N-acetylglucosamine-6-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001502///cartilage condensation+++GO:0001822///kidney development+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002063///chondrocyte development+++GO:0003094///glomerular filtration+++GO:0006790///sulfur compound metabolic process+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0014846///esophagus smooth muscle contraction+++GO:0016525///negative regulation of angiogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030201///heparan sulfate proteoglycan metabolic process+++GO:0030336///negative regulation of cell migration+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0032836///glomerular basement membrane development+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0036022///limb joint morphogenesis+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048706///embryonic skeletal system development+++GO:0051216///cartilage development+++GO:0060348///bone development+++GO:0060384///innervation+++GO:0060686///negative regulation of prostatic bud formation 240726 240726 'Slco5a1' mRNA 9 6 15 0.06 0.04 0.1 0.13 0.1 0.06 0.066666667 0.096666667 24 19 11 10 18 0.306896545 0.81742892 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport 24074 24074 'Taf7' mRNA 337 332 300 5.57 5.4 5.26 5.76 5.41 5.31 5.41 5.493333333 401 368 358 323 375.6666667 0.168655951 0.207019127 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm+++GO:0033276///transcription factor TFTC complex+++GO:0071339///MLL1 complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001097///TFIIH-class transcription factor complex binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0035035///histone acetyltransferase binding+++GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0061628///H3K27me3 modified histone binding+++GO:0106140///P-TEFb complex binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006352///DNA-templated transcription, initiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006469///negative regulation of protein kinase activity+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0035067///negative regulation of histone acetylation+++GO:0045344///negative regulation of MHC class I biosynthetic process+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0090241///negative regulation of histone H4 acetylation" 24075 24075 'Taf10' mRNA 88 75 63 8.11 6.82 6.13 12.82 10.29 13.37 7.02 12.16 160 125 161 75.33333333 148.6666667 8.66E-05 0.971136738 03022///Basal transcription factors GO:0000124///SAGA complex+++GO:0000125///PCAF complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0048471///perinuclear region of cytoplasm GO:0003677///DNA binding+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0019899///enzyme binding+++GO:0030331///estrogen receptor binding+++GO:0042802///identical protein binding+++GO:0070063///RNA polymerase binding+++GO:1990841///promoter-specific chromatin binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001889///liver development+++GO:0006352///DNA-templated transcription, initiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0009790///embryo development+++GO:0010468///regulation of gene expression+++GO:0016573///histone acetylation+++GO:0016578///histone deubiquitination+++GO:0034622///cellular protein-containing complex assembly+++GO:0035264///multicellular organism growth+++GO:0043966///histone H3 acetylation+++GO:0051101///regulation of DNA binding+++GO:0070365///hepatocyte differentiation" 240752 240752 'Pik3c2b' mRNA 379.91 342.23 314.28 2.53 2.23 2.2 1.25 1.39 1.37 2.32 1.336666667 218.34 235 227.25 345.4733333 226.8633333 6.20E-05 -0.615181192 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++05132///Salmonella infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0001727///lipid kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0035091///phosphatidylinositol binding+++GO:0052742///phosphatidylinositol kinase activity GO:0009267///cellular response to starvation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016236///macroautophagy+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0043491///protein kinase B signaling+++GO:0046834///lipid phosphorylation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:1905037///autophagosome organization 240753 240753 'Plekha6' mRNA 994 860 810 7.19 6.14 6.26 3.32 3.31 3.12 6.53 3.25 523 517 479 888 506.3333333 2.67E-14 -0.820570789 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 240754 240754 'Lax1' mRNA 10 8 9 0.25 0.19 0.2 0.37 0.29 0.34 0.213333333 0.333333333 18 14 16 9 16 0.297261425 0.815584429 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding GO:0000188///inactivation of MAPK activity+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002377///immunoglobulin production+++GO:0006955///immune response+++GO:0035556///intracellular signal transduction+++GO:0042113///B cell activation+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046649///lymphocyte activation+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0050868///negative regulation of T cell activation+++GO:0051249///regulation of lymphocyte activation 240755 240755 'Mgat4f' mRNA 7 4 8 0.18 0.1 0.28 0.04 0.03 0.05 0.186666667 0.04 2 1 2 6.333333333 1.666666667 0.165864657 -1.951338755 GO:0008375///acetylglucosaminyltransferase activity GO:0006487///protein N-linked glycosylation 240756 240756 'Klhl12' mRNA 939 1030 1088 15.62 16.83 19.15 11.6 9.86 10.71 17.2 10.72333333 805 668 724 1019 732.3333333 8.70E-06 -0.492819482 GO:0030127///COPII vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding GO:0006513///protein monoubiquitination+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development+++GO:0016055///Wnt signaling pathway+++GO:0016192///vesicle-mediated transport+++GO:0016567///protein ubiquitination+++GO:0048208///COPII vesicle coating 240776 240776 'Kcnt2' mRNA 14 2 13 0.11 0.04 0.13 0.12 0.11 0.16 0.093333333 0.13 11 9 16 9.666666667 12 0.804059152 0.285133904 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005228///intracellular sodium activated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0070089///chloride-activated potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane 240816 240816 'Rgsl1' mRNA 7 14 8 0.06 0.14 0.08 0.06 0.08 0.03 0.093333333 0.056666667 5 6 3 9.666666667 4.666666667 0.323358237 -1.054796956 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 240817 240817 'Teddm2' mRNA 3 4 0 0.11 0.14 0 0 0.03 0.03 0.083333333 0.02 0 1 1 2.333333333 0.666666667 0.512668052 -1.77386877 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 240819 240819 'Teddm1a' mRNA 1 3 2 0.04 0.12 0.09 0.04 0.04 0.11 0.083333333 0.063333333 0.97 1 3 2 1.656666667 0.830367682 -0.585789778 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 24083 24083 'Natd1' mRNA 997 955 881 12.91 12.17 12.1 11.56 11.37 12.06 12.39333333 11.66333333 1027 987 1038 944.3333333 1017.333333 0.349174496 0.096919704 GO:0005575///cellular_component 240832 240832 'Tor1aip2' mRNA 1623 1861.61 1791.15 29.46 33.21 34.74 54.85 46.44 46.14 32.47 49.14333333 3406.5 2855.49 2829.78 1758.586667 3030.59 1.30E-19 0.770442198 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0051117///ATPase binding GO:0007029///endoplasmic reticulum organization+++GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061024///membrane organization+++GO:0090435///protein localization to nuclear envelope 24084 24084 'Tekt2' mRNA 1124 1173 970 42.2 43.22 38.35 4.22 3.28 5.1 41.25666667 4.2 130 99 150 1089 126.3333333 5.45E-119 -3.117114278 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0036159///inner dynein arm assembly+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility 240843 240843 'Brinp2' mRNA 24 28 24 0.3 0.36 0.33 0.05 0.04 0.09 0.33 0.06 4 3 8 25.33333333 5 9.25E-04 -2.351161256 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0045666///positive regulation of neuron differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0071300///cellular response to retinoic acid 24086 24086 'Tlk2' mRNA 544 495 417 6.55 6.17 5.46 5.38 4.81 4.57 6.06 4.92 523 455 460 485.3333333 479.3333333 0.867188599 -0.027218616 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0001672///regulation of chromatin assembly or disassembly+++GO:0006325///chromatin organization+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035556///intracellular signal transduction+++GO:0071480///cellular response to gamma radiation 240869 240869 'Zbtb37' mRNA 771.53 736.6 647.12 5.03 4.64 4.45 2.6 2.39 2.63 4.706666667 2.54 516.01 430.63 475.79 718.4166667 474.1433333 5.44E-08 -0.610705136 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 24087 24087 'Tll2' mRNA 22 10 14 0.19 0.1 0.13 0.07 0.05 0.03 0.14 0.05 10 7 4.99 15.33333333 7.33 0.178003696 -1.147020878 GO:0005576///extracellular region GO:0004222///metalloendopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0048632///negative regulation of skeletal muscle tissue growth 240873 240873 'Tnfsf18' mRNA 1 0 1 0.03 0 0.03 0.14 0.37 0.12 0.02 0.21 6 15 5 0.666666667 8.666666667 0.0198788 3.688938415 04060///Cytokine-cytokine receptor interaction GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0032813///tumor necrosis factor receptor superfamily binding+++GO:0042802///identical protein binding "GO:0002250///adaptive immune response+++GO:0002309///T cell proliferation involved in immune response+++GO:0002376///immune system process+++GO:0002687///positive regulation of leukocyte migration+++GO:0006955///immune response+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0032649///regulation of interferon-gamma production+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0035741///activated CD4-positive, alpha-beta T cell proliferation+++GO:0042129///regulation of T cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043254///regulation of protein complex assembly+++GO:0045785///positive regulation of cell adhesion+++GO:0050729///positive regulation of inflammatory response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071637///regulation of monocyte chemotactic protein-1 production+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:2000329///negative regulation of T-helper 17 cell lineage commitment+++GO:2000348///regulation of CD40 signaling pathway+++GO:2000508///regulation of dendritic cell chemotaxis" 240879 240879 'Mettl11b' mRNA 68 53 57 2.41 1.84 1.96 0.58 0.53 0.49 2.07 0.533333333 23 16 14 59.33333333 17.66666667 2.98E-05 -1.762520522 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0071885///N-terminal protein N-methyltransferase activity GO:0006480///N-terminal protein amino acid methylation+++GO:0032259///methylation 24088 24088 'Tlr2' mRNA 505 581 449 9.72 11.02 9.16 31.97 31.12 29.72 9.966666667 30.93666667 1906 1812 1716 511.6666667 1811.333333 1.93E-88 1.814976195 04145///Phagosome+++04151///PI3K-Akt signaling pathway+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++05132///Salmonella infection+++05134///Legionellosis+++05140///Leishmaniasis+++05142///Chagas disease+++05144///Malaria+++05145///Toxoplasmosis+++05146///Amoebiasis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0035354///Toll-like receptor 1-Toll-like receptor 2 protein complex+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0042995///cell projection+++GO:0044297///cell body+++GO:0045121///membrane raft "GO:0001530///lipopolysaccharide binding+++GO:0001540///amyloid-beta binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0035325///Toll-like receptor binding+++GO:0038023///signaling receptor activity+++GO:0038187///pattern recognition receptor activity+++GO:0042497///triacyl lipopeptide binding+++GO:0042498///diacyl lipopeptide binding+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating+++GO:0070891///lipoteichoic acid binding+++GO:0071723///lipopeptide binding" GO:0001666///response to hypoxia+++GO:0001774///microglial cell activation+++GO:0001775///cell activation+++GO:0001817///regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002237///response to molecule of bacterial origin+++GO:0002238///response to molecule of fungal origin+++GO:0002376///immune system process+++GO:0002687///positive regulation of leukocyte migration+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0002752///cell surface pattern recognition receptor signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006691///leukotriene metabolic process+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007252///I-kappaB phosphorylation+++GO:0007612///learning+++GO:0008285///negative regulation of cell proliferation+++GO:0009617///response to bacterium+++GO:0009636///response to toxic substance+++GO:0010628///positive regulation of gene expression+++GO:0014005///microglia development+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032289///central nervous system myelin formation+++GO:0032493///response to bacterial lipoprotein+++GO:0032494///response to peptidoglycan+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032722///positive regulation of chemokine production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032741///positive regulation of interleukin-18 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0042495///detection of triacyl bacterial lipopeptide+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046209///nitric oxide metabolic process+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0050765///negative regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051964///negative regulation of synapse assembly+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070542///response to fatty acid+++GO:0071221///cellular response to bacterial lipopeptide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071224///cellular response to peptidoglycan+++GO:0071346///cellular response to interferon-gamma+++GO:0071726///cellular response to diacyl bacterial lipopeptide+++GO:0071727///cellular response to triacyl bacterial lipopeptide+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903974///positive regulation of cellular response to macrophage colony-stimulating factor stimulus+++GO:1904417///positive regulation of xenophagy+++GO:1904466///positive regulation of matrix metallopeptidase secretion 240880 240880 'Scyl3' mRNA 493.25 452.91 424.15 5.13 4.81 4.89 3.69 4.89 5 4.943333333 4.526666667 381.25 491.65 499.48 456.77 457.46 0.981773838 -0.005768866 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0021522///spinal cord motor neuron differentiation+++GO:0034613///cellular protein localization+++GO:0048666///neuron development 240888 240888 'Gpr161' mRNA 58.19 55.85 58.97 0.42 0.4 0.45 0.29 0.31 0.27 0.423333333 0.29 46.97 47.91 42.02 57.67 45.63333333 0.372116056 -0.353979512 04340///Hedgehog signaling pathway GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0060170///ciliary membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 240892 240892 'Dusp27' mRNA 16 26 15 0.21 0.34 0.21 0.03 0.07 0.02 0.253333333 0.04 3 6 2 19 3.666666667 0.004812281 -2.373869094 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0030017///sarcomere GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0033549///MAP kinase phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0043409///negative regulation of MAPK cascade 240899 240899 'Lrrc52' mRNA 0 2 0 0 0.11 0 0 0 0 0.036666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0044325///ion channel binding+++GO:0099104///potassium channel activator activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0022414///reproductive process+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity 240913 240913 'Adamts4' mRNA 28.69 28.35 17.12 0.24 0.23 0.15 2 1.98 1.88 0.206666667 1.953333333 273.97 265.28 249.8 24.72 263.0166667 3.23E-41 3.423071233 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016607///nuclear speck+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0042742///defense response to bacterium 240916 240916 'Vsig8' mRNA 6 4 5 0.19 0.13 0.17 0.11 0.34 0.23 0.163333333 0.226666667 4 12 8 5 8 0.58043879 0.672975573 GO:0005622///intracellular+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008150///biological_process 240960 240960 'Dnah14' mRNA 0 1 1 0 0 0 0.01 0 0 0 0.003333333 3 0 1 0.666666667 1.333333333 0.783277493 0.958742855 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0007018///microtubule-based movement+++GO:0060285///cilium-dependent cell motility 24099 24099 'Tnfsf13b' mRNA 9 16 17 0.31 0.54 0.62 1.56 1.73 1.41 0.49 1.566666667 53 57 46 14 52 5.43E-05 1.877724835 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04672///Intestinal immune network for IgA production+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0048018///receptor ligand activity GO:0001782///B cell homeostasis+++GO:0002377///immunoglobulin production+++GO:0002636///positive regulation of germinal center formation+++GO:0006955///immune response+++GO:0030183///B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031295///T cell costimulation+++GO:0031296///B cell costimulation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0050776///regulation of immune response 24100 24100 'Tpra1' mRNA 2281 2416 2354 63.04 64.38 68.75 67.8 63.92 65.01 65.39 65.57666667 2665 2461 2501 2350.333333 2542.333333 0.203388995 0.1002055 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0040016///embryonic cleavage+++GO:1901991///negative regulation of mitotic cell cycle phase transition 24102 24102 'Trex2' mRNA 1 0 0 0.06 0 0 0 0.06 0 0.02 0.02 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000287///magnesium ion binding+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0008853///exodeoxyribonuclease III activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0000738///DNA catabolic process, exonucleolytic+++GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 24105 24105 'Rbck1' mRNA 2459 2410 2441 58.02 55.77 61.29 50.45 45.8 43.32 58.36 46.52333333 2452 2168 2041 2436.666667 2220.333333 0.084166214 -0.148201423 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0071797///LUBAC complex GO:0003690///double-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding GO:0000209///protein polyubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050852///T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051220///cytoplasmic sequestering of protein+++GO:0060546///negative regulation of necroptotic process+++GO:0097039///protein linear polyubiquitination+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 241062 241062 'Pgap1' mRNA 149 121 131 0.74 0.59 0.69 1.1 0.82 0.93 0.673333333 0.95 257 186 210 133.6666667 217.6666667 8.68E-04 0.688531663 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0050185///phosphatidylinositol deacylase activity" GO:0006505///GPI anchor metabolic process+++GO:0006506///GPI anchor biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007605///sensory perception of sound+++GO:0009880///embryonic pattern specification+++GO:0009948///anterior/posterior axis specification+++GO:0015031///protein transport+++GO:0021871///forebrain regionalization+++GO:0060322///head development+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport 241066 241066 'Carf' mRNA 501.97 566.01 549.3 4.86 5.27 5.6 2.45 2.2 2.66 5.243333333 2.436666667 289.05 254.81 305.51 539.0933333 283.1233333 2.14E-12 -0.943715585 GO:0001652///granular component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035865///cellular response to potassium ion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0061400///positive regulation of transcription from RNA polymerase II promoter in response to calcium ion+++GO:0071277///cellular response to calcium ion 241070 241070 'Gpr1' mRNA 0 1 1 0 0.03 0.03 0.03 0.06 0.09 0.02 0.06 1 2 3 0.666666667 2 0.557456194 1.570384984 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle GO:0004930///G protein-coupled receptor activity+++GO:0042277///peptide binding+++GO:0042923///neuropeptide binding+++GO:0097003///adipokinetic hormone receptor activity+++GO:0097004///adipokinetic hormone binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0042593///glucose homeostasis 241073 241073 'Dytn' mRNA 538 567 530 12.38 12.85 12.94 0.86 0.88 0.79 12.72333333 0.843333333 43 43 38 545 41.33333333 3.47E-90 -3.732514952 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0099536///synaptic signaling 241075 241075 'Plekhm3' mRNA 951 895 624 5.81 5.38 4.06 3.43 3.24 3.83 5.083333333 3.5 642 591 694 823.3333333 642.3333333 0.007950314 -0.362457562 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0045445///myoblast differentiation 24108 24108 'Ubd' mRNA 8 5 4 0.56 0.34 0.29 4.84 4.97 5.08 0.396666667 4.963333333 80 80 81 5.666666667 80.33333333 8.42E-15 3.817192656 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016235///aggresome GO:0005515///protein binding+++GO:0070628///proteasome binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032446///protein modification by small protein conjugation+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0070842///aggresome assembly+++GO:1901990///regulation of mitotic cell cycle phase transition 24109 24109 'Ubl3' mRNA 4875 4805 3950 126.36 123.92 110.73 56.39 58.87 59.75 120.3366667 58.33666667 2376 2513 2506 4543.333333 2465 2.23E-36 -0.889232335 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 24110 24110 'Usp18' mRNA 996 1045 1075 32.48 33.59 37.19 56.21 60.64 59.81 34.42 58.88666667 1981 2086 2040 1038.666667 2035.666667 2.49E-30 0.957933702 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019785///ISG15-specific protease activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009617///response to bacterium+++GO:0016579///protein deubiquitination+++GO:0035634///response to stilbenoid+++GO:0050727///regulation of inflammatory response+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway 24111 24111 'Uts2' mRNA 1 0 0 0.15 0 0 0 0 0 0.05 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0051429///corticotropin-releasing hormone receptor binding+++GO:0051431///corticotropin-releasing hormone receptor 2 binding "GO:0001666///response to hypoxia+++GO:0003105///negative regulation of glomerular filtration+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007586///digestion+++GO:0008217///regulation of blood pressure+++GO:0008283///cell proliferation+++GO:0009755///hormone-mediated signaling pathway+++GO:0010459///negative regulation of heart rate+++GO:0010460///positive regulation of heart rate+++GO:0010629///negative regulation of gene expression+++GO:0010763///positive regulation of fibroblast migration+++GO:0010841///positive regulation of circadian sleep/wake cycle, wakefulness+++GO:0031669///cellular response to nutrient levels+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0033574///response to testosterone+++GO:0033685///negative regulation of luteinizing hormone secretion+++GO:0035811///negative regulation of urine volume+++GO:0035814///negative regulation of renal sodium excretion+++GO:0042493///response to drug+++GO:0045597///positive regulation of cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045776///negative regulation of blood pressure+++GO:0045777///positive regulation of blood pressure+++GO:0046005///positive regulation of circadian sleep/wake cycle, REM sleep+++GO:0046676///negative regulation of insulin secretion+++GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0097746///regulation of blood vessel diameter" 241112 241112 'Catip' mRNA 104 87 96 3.02 2.43 2.86 2.5 1.12 1.36 2.77 1.66 97 47 51 95.66666667 65 0.096156436 -0.5773951 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0030041///actin filament polymerization+++GO:0044782///cilium organization 241113 241113 'Prkag3' mRNA 11 9.12 4 0.21 0.17 0.08 0.17 0.15 0.05 0.153333333 0.123333333 11 9 3 8.04 7.666666667 0.961780758 -0.062484079 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04371///Apelin signaling pathway+++04530///Tight junction+++04710///Circadian rhythm+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05410///Hypertrophic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031588///nucleotide-activated protein kinase complex GO:0000166///nucleotide binding+++GO:0004679///AMP-activated protein kinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0032559///adenyl ribonucleotide binding GO:0005978///glycogen biosynthetic process+++GO:0006096///glycolytic process+++GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0042149///cellular response to glucose starvation+++GO:0050790///regulation of catalytic activity+++GO:0071900///regulation of protein serine/threonine kinase activity 241116 241116 'Cfap65' mRNA 1996 2070 1839 18.52 18.99 18.12 1.39 1.42 1.18 18.54333333 1.33 173 173 143 1968.333333 163 1.14E-262 -3.60440488 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097225///sperm midpiece GO:0007288///sperm axoneme assembly+++GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility 241118 241118 'Asic4' mRNA 31 9 5 0.61 0.19 0.11 0 0.02 0.08 0.303333333 0.033333333 0 1 4 15 1.666666667 0.008799338 -3.157365969 04750///Inflammatory mediator regulation of TRP channels GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005272///sodium channel activity+++GO:0015280///ligand-gated sodium channel activity GO:0001662///behavioral fear response+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0035725///sodium ion transmembrane transport 241128 241128 'Fam124b' mRNA 1 4 7 0.03 0.08 0.14 0.07 0.21 0.23 0.083333333 0.17 4 12 12 4 9.333333333 0.313098276 1.199914125 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 241134 241134 'Nyap2' mRNA 1 0 1 0.01 0 0.01 0.02 0 0.01 0.006666667 0.01 4 0 1 0.666666667 1.666666667 0.692487645 1.271876127 GO:0005515///protein binding GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0048812///neuron projection morphogenesis 24115 24115 'Best1' mRNA 506 549 429 13.78 14.72 12.39 7.39 7.74 7.1 13.63 7.41 312 319 290 494.6666667 307 1.64E-07 -0.695884975 GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0034707///chloride channel complex GO:0005254///chloride channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0030321///transepithelial chloride transport+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0051924///regulation of calcium ion transport+++GO:1902476///chloride transmembrane transport 241158 241158 'Ankmy1' mRNA 30.19 26.68 18.31 0.34 0.3 0.24 0.15 0.18 0.12 0.293333333 0.15 13.48 16.01 10.38 25.06 13.29 0.140312748 -0.927131631 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 24116 24116 'Nelfa' mRNA 935 1011 919 21.38 22.76 22.24 19.8 18.08 18.13 22.12666667 18.67 997 889 883 955 923 0.606283645 -0.061116434 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032021///NELF complex GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051571///positive regulation of histone H3-K4 methylation 24117 24117 'Wif1' mRNA 1861 1936 1681 46.71 47.85 44.76 63.38 67.19 67.77 46.44 66.11333333 2904 3006 3006 1826 2972 3.14E-25 0.693576458 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0009986///cell surface GO:0005102///signaling receptor binding+++GO:0017147///Wnt-protein binding GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0048856///anatomical structure development 241175 241175 'Cntnap5b' mRNA 6.04 9.01 17.08 0.03 0.06 0.1 0 0.01 0 0.063333333 0.003333333 0 1 0 10.71 0.333333333 0.002540792 -4.928562501 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007155///cell adhesion 241197 241197 'Serpinb10' mRNA 1 0 1 0.02 0 0.03 0.16 0.04 0.04 0.016666667 0.08 6 3 3 0.666666667 4 0.200723525 2.554930811 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 241201 241201 'Cdh7' mRNA 8 7.38 10.17 0.05 0.07 0.09 0.07 0.02 0.03 0.07 0.04 8 3 2.96 8.516666667 4.653333333 0.410923977 -0.971871064 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 241226 241226 'Itga8' mRNA 278 243 231 2.53 2.19 2.22 2.39 2.68 2.45 2.313333333 2.506666667 301 331 302 250.6666667 311.3333333 0.069357156 0.303208083 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032591///dendritic spine membrane+++GO:0043204///perikaryon+++GO:0045177///apical part of cell GO:0046872///metal ion binding GO:0001656///metanephros development+++GO:0001822///kidney development+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007613///memory+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0042472///inner ear morphogenesis+++GO:0045184///establishment of protein localization+++GO:0048745///smooth muscle tissue development+++GO:2000721///positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation 241230 241230 'St8sia6' mRNA 10 9 6 0.17 0.15 0.11 0.21 0.39 0.36 0.143333333 0.32 14 25 23 8.333333333 20.66666667 0.065962568 1.310052286 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003828///alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0001835///blastocyst hatching+++GO:0006486///protein glycosylation+++GO:0006491///N-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0009100///glycoprotein metabolic process+++GO:0009247///glycolipid biosynthetic process+++GO:0009311///oligosaccharide metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0097503///sialylation 241263 241263 'Gpr158' mRNA 102 95 81 0.75 0.69 0.63 0.08 0.05 0.08 0.69 0.07 12 7 12 92.66666667 10.33333333 6.23E-15 -3.174871838 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0072659///protein localization to plasma membrane 24127 24127 'Xrn1' mRNA 1143.8 1094.39 1046.38 6.17 5.8 6 4.78 4.31 5.09 5.99 4.726666667 1004.32 889.14 1072.6 1094.856667 988.6866667 0.129246521 -0.158713911 03008///Ribosome biogenesis in eukaryotes+++03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0002151///G-quadruplex RNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004534///5'-3' exoribonuclease activity+++GO:0005515///protein binding+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0051880///G-quadruplex DNA binding "GO:0000723///telomere maintenance+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006396///RNA processing+++GO:0007569///cell aging+++GO:0016075///rRNA catabolic process+++GO:0017148///negative regulation of translation+++GO:0033574///response to testosterone+++GO:0051321///meiotic cell cycle+++GO:0071028///nuclear mRNA surveillance+++GO:0071044///histone mRNA catabolic process+++GO:0071409///cellular response to cycloheximide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:1905795///cellular response to puromycin" 241274 241274 'Pnpla7' mRNA 292 290 250 3.07 3.05 2.91 7.71 7.63 7.29 3.01 7.543333333 775 772 733 277.3333333 760 1.56E-36 1.444885141 00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102545///phosphatidyl phospholipase B activity GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0034638///phosphatidylcholine catabolic process 241275 241275 'Noxa1' mRNA 2 5 6 0.07 0.17 0.22 0.18 0 0.06 0.153333333 0.08 6 0 2 4.333333333 2.666666667 0.692487645 -0.740847186 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043020///NADPH oxidase complex GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0017124///SH3 domain binding+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0006801///superoxide metabolic process+++GO:0010310///regulation of hydrogen peroxide metabolic process+++GO:0042554///superoxide anion generation+++GO:0050790///regulation of catalytic activity+++GO:0060263///regulation of respiratory burst 24128 24128 'Xrn2' mRNA 1069 1173 1160 15.93 17.29 18.24 23.48 21.98 22.76 17.15333333 22.74 1801 1642 1697 1134 1713.333333 3.68E-12 0.581707122 03008///Ribosome biogenesis in eukaryotes+++03018///RNA degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016235///aggresome GO:0000175///3'-5'-exoribonuclease activity+++GO:0001147///transcription termination site sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004534///5'-3' exoribonuclease activity+++GO:0005515///protein binding+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0000738///DNA catabolic process, exonucleolytic+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006353///DNA-templated transcription, termination+++GO:0006397///mRNA processing+++GO:0007017///microtubule-based process+++GO:0007283///spermatogenesis+++GO:0016070///RNA metabolic process+++GO:0021766///hippocampus development+++GO:0030182///neuron differentiation+++GO:0060041///retina development in camera-type eye+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 241289 241289 'Ppp1r26' mRNA 316 356 323 3.06 3.37 3.3 1.4 1.37 1.34 3.243333333 1.37 168 161 157 331.6666667 162 5.16E-11 -1.045284239 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0004864///protein phosphatase inhibitor activity GO:0010923///negative regulation of phosphatase activity 241296 241296 'Lrrc8a' mRNA 3678 3468 3053 46.53 43.15 40.97 46.74 49.07 47.2 43.55 47.67 4253 4362 4160 3399.666667 4258.333333 1.91E-06 0.31612515 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034702///ion channel complex+++GO:1905103///integral component of lysosomal membrane GO:0005225///volume-sensitive anion channel activity+++GO:0005253///anion channel activity+++GO:0042802///identical protein binding GO:0001678///cellular glucose homeostasis+++GO:0002329///pre-B cell differentiation+++GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006884///cell volume homeostasis+++GO:0006970///response to osmotic stress+++GO:0007283///spermatogenesis+++GO:0015734///taurine transport+++GO:0015810///aspartate transmembrane transport+++GO:0030154///cell differentiation+++GO:0032024///positive regulation of insulin secretion+++GO:0034214///protein hexamerization+++GO:0045663///positive regulation of myoblast differentiation+++GO:0098656///anion transmembrane transport+++GO:1902476///chloride transmembrane transport 241303 241303 'Fam78a' mRNA 143 145 72 2 1.99 1.03 2.29 2.02 1.83 1.673333333 2.046666667 194 166 148 120 169.3333333 0.068168449 0.495929092 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 241308 241308 'Ralgps1' mRNA 436 500 431 3.76 4.27 3.97 2.02 2.05 2 4 2.023333333 268 267 258 455.6666667 264.3333333 3.57E-09 -0.795883315 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0032485///regulation of Ral protein signal transduction+++GO:0050790///regulation of catalytic activity 24131 24131 'Ldb3' mRNA 1248 1228 1161 17.45 16.77 16.02 1.1 1.35 1.46 16.74666667 1.303333333 107 112 124 1212.333333 114.3333333 2.38E-171 -3.417358003 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0030018///Z disc+++GO:0031143///pseudopodium+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0045214///sarcomere organization+++GO:0061061///muscle structure development 241311 241311 'Zbtb34' mRNA 147 120 114 1.2 0.96 0.99 1.02 1.18 1.3 1.05 1.166666667 144 162 177 127 161 0.16269544 0.333789144 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 24132 24132 'Zfp53' mRNA 431.28 340.6 367.59 5.05 4.05 4.96 5.86 5.27 5.71 4.686666667 5.613333333 494.5 439.37 455.17 379.8233333 463.0133333 0.062612522 0.273551175 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 241322 241322 'Zbtb6' mRNA 181.48 197 170 2.15 2.29 2.13 2.05 1.62 2.16 2.19 1.943333333 199.11 153.57 204 182.8266667 185.56 0.975527512 0.009416756 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 241324 241324 'Crb2' mRNA 184 195 167 1.53 1.59 1.47 1.77 2.02 2.03 1.53 1.94 245 274 273 182 264 0.00246584 0.528043635 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0035003///subapical complex+++GO:0045177///apical part of cell GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0044877///protein-containing complex binding GO:0001707///mesoderm formation+++GO:0001756///somitogenesis+++GO:0001895///retina homeostasis+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0010470///regulation of gastrulation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010951///negative regulation of endopeptidase activity+++GO:0014028///notochord formation+++GO:0030010///establishment of cell polarity+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0045494///photoreceptor cell maintenance+++GO:0046549///retinal cone cell development+++GO:0055111///ingression involved in gastrulation with mouth forming second+++GO:0072359///circulatory system development 241327 241327 'Olfml2a' mRNA 649 676 620 15.06 15.44 15.26 13.68 14.13 13.86 15.25333333 13.89 678 684 665 648.3333333 675.6666667 0.727489395 0.048843602 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0042802///identical protein binding+++GO:0050840///extracellular matrix binding GO:0030198///extracellular matrix organization 24135 24135 'Zfp68' mRNA 1523 1543 1577 17.35 17.3 19.1 11.16 11.58 10.52 17.91666667 11.08666667 1127 1144 1028 1547.666667 1099.666667 7.62E-09 -0.5061982 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 24136 24136 'Zeb2' mRNA 804 744 689 4.59 4.18 4.19 9.34 8.03 8.8 4.32 8.723333333 1873 1583 1722 745.6666667 1726 1.65E-43 1.199268433 05206///MicroRNAs in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001755///neural crest cell migration+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development+++GO:0021540///corpus callosum morphogenesis+++GO:0021766///hippocampus development+++GO:0021846///cell proliferation in forebrain+++GO:0021957///corticospinal tract morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0048066///developmental pigmentation+++GO:0048598///embryonic morphogenesis+++GO:0048668///collateral sprouting+++GO:0048856///anatomical structure development+++GO:0050772///positive regulation of axonogenesis+++GO:0061373///mammillary axonal complex development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097324///melanocyte migration+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:1903056///regulation of melanosome organization 241391 241391 'Galnt5' mRNA 2 0 0 0.03 0 0 0.01 0 0.02 0.01 0.01 1 0 1 0.666666667 0.666666667 0.999865452 5.07E-04 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation 241431 241431 'Xirp2' mRNA 2960 2973 2937 12.91 12.74 13.58 0.99 0.92 0.92 13.07666667 0.943333333 262 238 235 2956.666667 245 0 -3.606115008 GO:0001725///stress fiber+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030018///Z disc+++GO:0030054///cell junction GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding+++GO:0051393///alpha-actinin binding GO:0003281///ventricular septum development+++GO:0007015///actin filament organization+++GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0045216///cell-cell junction organization+++GO:0055008///cardiac muscle tissue morphogenesis 241447 241447 'Cers6' mRNA 1314 1225 1077 9.22 8.22 7.77 6.89 5.91 6.32 8.403333333 6.373333333 1180 976 1050 1205.333333 1068.666667 0.06900502 -0.184236361 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006954///inflammatory response+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process 241452 241452 'Dhrs9' mRNA 8 0 1 0.16 0 0.02 0.8 0.77 1 0.06 0.856666667 47 44 57 3 49.33333333 1.42E-08 4.033845106 00830///Retinol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity" GO:0002138///retinoic acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008209///androgen metabolic process+++GO:0042448///progesterone metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process 241489 241489 'Pde11a' mRNA 28 31 29 0.19 0.2 0.19 0.16 0.1 0.09 0.193333333 0.116666667 29 18 17 29.33333333 21.33333333 0.414072737 -0.47536292 00230///Purine metabolism+++04934///Cushing syndrome+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043204///perikaryon "GO:0003824///catalytic activity+++GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004118///cGMP-stimulated cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030553///cGMP binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0007165///signal transduction+++GO:0008152///metabolic process+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0043951///negative regulation of cAMP-mediated signaling 241490 241490 'Rbm45' mRNA 246 264 211 7.42 7.85 6.75 8.9 9.33 9.44 7.34 9.223333333 339 347 348 240.3333333 344.6666667 7.42E-04 0.512051761 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008150///biological_process+++GO:0030154///cell differentiation 241494 241494 'Zfp385b' mRNA 273.24 251.04 203.39 2.05 1.93 1.73 0.65 0.6 0.73 1.903333333 0.66 121.66 92.99 130.62 242.5566667 115.09 7.19E-08 -1.092369692 GO:0005634///nucleus GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 241514 241514 'Zfp804a' mRNA 0 1 0 0 0.01 0 0.06 0.05 0.02 0.003333333 0.043333333 6 4 2 0.333333333 4 0.107533593 3.463334965 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:1901588///dendritic microtubule GO:0046872///metal ion binding GO:0010628///positive regulation of gene expression+++GO:0010975///regulation of neuron projection development+++GO:0010976///positive regulation of neuron projection development+++GO:1902952///positive regulation of dendritic spine maintenance 241520 241520 'Fam171b' mRNA 391 494 455 3.66 4.56 4.52 2.16 1.97 1.97 4.246666667 2.033333333 266 237 235 446.6666667 246 3.63E-09 -0.873923991 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 241525 241525 'Ypel4' mRNA 234 263 217 4.86 4.98 4.43 4.48 4.52 4.25 4.756666667 4.416666667 257 259 265 238 260.3333333 0.542838758 0.120330198 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 241528 241528 'Lrrc55' mRNA 2 1 13 0.02 0.01 0.12 0.07 0.13 0.1 0.05 0.1 8 16 12 5.333333333 12 0.324155423 1.121040864 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0099104///potassium channel activator activity GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity 241547 241547 'Harbi1' mRNA 562.01 630.85 563.2 10.81 12.37 10.94 8.3 8.15 8.24 11.37333333 8.23 555.81 538.06 553.44 585.3533333 549.1033333 0.437521696 -0.103476656 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0034451///centriolar satellite GO:0003674///molecular_function+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process 241556 241556 'Tspan18' mRNA 89 126 120 1.28 1.82 1.84 1.89 1.96 1.54 1.646666667 1.796666667 151 155 120 111.6666667 142 0.218612788 0.332809845 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 241568 241568 'Lrrc4c' mRNA 587.01 593.92 567.93 5.38 5.41 6.09 1.78 2.24 1.66 5.626666667 1.893333333 258.92 288.18 248 582.9533333 265.0333333 2.37E-19 -1.1485368 04360///Axon guidance+++04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0098632///cell-cell adhesion mediator activity GO:0050770///regulation of axonogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0099560///synaptic membrane adhesion 241576 241576 'Ldlrad3' mRNA 1856 1769 1744 25.72 24.13 25.65 15.18 14.08 14.29 25.16666667 14.51666667 1260 1142 1149 1789.666667 1183.666667 3.71E-15 -0.609033539 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding GO:0006898///receptor-mediated endocytosis+++GO:0070613///regulation of protein processing 241589 241589 'D430041D05Rik' mRNA 3248 3414 1832 13.31 13.37 8.26 3.59 3.3 4.11 11.64666667 3.666666667 973 947 1164 2831.333333 1028 5.69E-08 -1.459435127 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 241593 241593 'Pin1rt1' mRNA 1 11 4 0.07 0.74 0.29 0.3 0.06 0.37 0.366666667 0.243333333 5 1 6 5.333333333 4 0.809103629 -0.41997736 04622///RIG-I-like receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0036064///ciliary basal body+++GO:0043005///neuron projection+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0008013///beta-catenin binding+++GO:0016853///isomerase activity+++GO:0016859///cis-trans isomerase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0032794///GTPase activating protein binding+++GO:0050815///phosphoserine residue binding+++GO:0050816///phosphothreonine residue binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001666///response to hypoxia+++GO:0001932///regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010468///regulation of gene expression+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0042177///negative regulation of protein catabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0060393///regulation of pathway-restricted SMAD protein phosphorylation+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900180///regulation of protein localization to nucleus+++GO:1902430///negative regulation of amyloid-beta formation+++GO:2000146///negative regulation of cell motility 241612 241612 'Slc5a12' mRNA 24 20 29 0.25 0.29 0.32 0.08 0 0.04 0.286666667 0.04 7 0 2 24.33333333 3 3.82E-04 -3.051343463 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0035873///lactate transmembrane transport+++GO:0055085///transmembrane transport 241624 241624 'Exd1' mRNA 171.69 185.11 207.01 1.84 2.17 2.56 1.62 1.49 1.43 2.19 1.513333333 145.04 134.07 126.44 187.9366667 135.1833333 0.021742027 -0.491467332 GO:0005737///cytoplasm+++GO:0043186///P granule+++GO:1990923///PET complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004527///exonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0042803///protein homodimerization activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 241627 241627 'Wdr76' mRNA 91 95 83 1.15 1.21 1.12 1.69 1.46 1.86 1.16 1.67 151 128 159 89.66666667 146 0.003313795 0.69247371 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0090734///site of DNA damage GO:0003677///DNA binding+++GO:0019899///enzyme binding GO:0006974///cellular response to DNA damage stimulus+++GO:2000001///regulation of DNA damage checkpoint 241633 241633 'Atp8b4' mRNA 26 21 11 0.29 0.2 0.15 2.38 2.75 1.81 0.213333333 2.313333333 273 273 194 19.33333333 246.6666667 1.73E-35 3.667770894 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0007030///Golgi organization+++GO:0015914///phospholipid transport+++GO:0045332///phospholipid translocation 241634 241634 'Spdye4c' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0005575///cellular_component GO:0019901///protein kinase binding 241636 241636 'Tgm6' mRNA 3 2 0 0.06 0.04 0 0.02 0.03 0.02 0.033333333 0.023333333 1 2 1 1.666666667 1.333333333 0.908016792 -0.299968277 GO:0005737///cytoplasm "GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0018149///peptide cross-linking 241638 241638 'Lzts3' mRNA 168 97 216 2.08 1.15 2.85 2.52 1.44 1.79 2.026666667 1.916666667 229.83 127 161.99 160.3333333 172.94 0.863090843 0.072054231 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0030165///PDZ domain binding+++GO:0043621///protein self-association GO:0051260///protein homooligomerization+++GO:0061001///regulation of dendritic spine morphogenesis 241639 241639 'Fermt1' mRNA 87 70 78 0.88 0.7 0.85 1.09 0.83 0.91 0.81 0.943333333 124 92 100 78.33333333 105.3333333 0.158961886 0.412084647 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0071944///cell periphery GO:0005178///integrin binding+++GO:0051015///actin filament binding "GO:0001954///positive regulation of cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0033625///positive regulation of integrin activation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043616///keratinocyte proliferation+++GO:0051546///keratinocyte migration+++GO:0051886///negative regulation of timing of anagen+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0071711///basement membrane organization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090162///establishment of epithelial cell polarity+++GO:1903691///positive regulation of wound healing, spreading of epidermal cells+++GO:2000647///negative regulation of stem cell proliferation" 241656 241656 'Pak5' mRNA 44 54 42 0.55 0.66 0.56 0.13 0.15 0.06 0.59 0.113333333 12 13 5 46.66666667 10 1.59E-05 -2.231306929 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05170///Human immunodeficiency virus 1 infection+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007612///learning+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 241688 241688 'Dzank1' mRNA 990 1009 923 7.73 7.73 7.64 2.1 1.51 1.77 7.7 1.793333333 309 217 252 974 259.3333333 6.66E-57 -1.922231869 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0042462///eye photoreceptor cell development 241694 241694 'Ralgapa2' mRNA 681 671 547.27 3.72 3.66 3.2 2.25 1.98 2.28 3.526666667 2.17 465 408 468 633.09 447 2.10E-05 -0.510641147 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0032484///Ral protein signal transduction+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0060178///regulation of exocyst localization+++GO:0090630///activation of GTPase activity 241727 241727 'Snph' mRNA 111 133 143 1.3 1.53 1.78 0.31 0.36 0.63 1.536666667 0.433333333 31 34 60 129 41.66666667 1.64E-07 -1.644598454 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031966///mitochondrial membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0008017///microtubule binding+++GO:0017075///syntaxin-1 binding GO:0006906///vesicle fusion+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:0045806///negative regulation of endocytosis 241732 241732 'Tspyl3' mRNA 337 297 319 6.02 5.22 6.04 5.45 5.58 5.38 5.76 5.47 351 351 336 317.6666667 346 0.533819199 0.110459153 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0008150///biological_process 241764 241764 'L3mbtl1' mRNA 46.67 55.52 49.7 0.4 0.45 0.45 0.35 0.29 0.36 0.433333333 0.333333333 49.68 43.14 48.96 50.63 47.26 0.820630504 -0.111524602 GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0031491///nucleosome binding+++GO:0031493///nucleosomal histone binding+++GO:0032093///SAM domain binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007088///regulation of mitotic nuclear division+++GO:0030097///hemopoiesis+++GO:0040029///regulation of gene expression, epigenetic+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 241769 241769 'Kcnk15' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0071805///potassium ion transmembrane transport 241770 241770 'Rims4' mRNA 5 13 7 0.05 0.13 0.08 0.01 0.01 0.03 0.086666667 0.016666667 1 1 3 8.333333333 1.666666667 0.074263445 -2.324580409 GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse GO:0031267///small GTPase binding+++GO:0044325///ion channel binding GO:0006836///neurotransmitter transport+++GO:0006887///exocytosis+++GO:0042391///regulation of membrane potential+++GO:0050807///regulation of synapse organization+++GO:2000300///regulation of synaptic vesicle exocytosis 241794 241794 'Kcng1' mRNA 16 16 18 0.22 0.21 0.26 0.02 0.02 0.09 0.23 0.043333333 2 2 7 16.66666667 3.666666667 0.013109404 -2.197820001 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1902259///regulation of delayed rectifier potassium channel activity 241846 241846 'Lsm14b' mRNA 107 99 68 2.34 2.11 1.55 1.56 1.11 1.69 2 1.453333333 82 57 86 91.33333333 75 0.400825291 -0.29066968 GO:0003729///mRNA binding GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0008150///biological_process 241850 241850 'Abhd16b' mRNA 3 1 4 0.1 0.03 0.14 0.06 0.09 0.06 0.09 0.07 2 3 2 2.666666667 2.333333333 0.910577202 -0.219005706 GO:0005654///nucleoplasm+++GO:0016020///membrane GO:0004620///phospholipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047372///acylglycerol lipase activity GO:0006660///phosphatidylserine catabolic process+++GO:0052651///monoacylglycerol catabolic process+++GO:0098734///macromolecule depalmitoylation 241877 241877 'Slc10a5' mRNA 1 2 2 0.01 0.03 0.03 0.04 0 0.01 0.023333333 0.016666667 3 0 1 1.666666667 1.333333333 0.888990488 -0.35585177 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008508///bile acid:sodium symporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0015721///bile acid and bile salt transport+++GO:0055085///transmembrane transport 241915 241915 'Phc3' mRNA 1009 889 825 6.89 5.97 5.27 5.67 4.88 5.98 6.043333333 5.51 995 864 972 907.6666667 943.6666667 0.741082698 0.045356948 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0045892///negative regulation of transcription, DNA-templated" 241919 241919 'Slc7a14' mRNA 458.26 501.7 492.22 2.73 2.94 3.11 0.91 0.98 0.82 2.926666667 0.903333333 174.78 184.78 153.02 484.06 170.86 8.83E-25 -1.518313548 GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015171///amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0010923///negative regulation of phosphatase activity+++GO:0055085///transmembrane transport 241943 241943 'Ccdc144b' mRNA 7.64 3.31 1 0.17 0.07 0.02 0.08 0.08 0.1 0.086666667 0.086666667 4 4 5 3.983333333 4.333333333 0.875458715 0.247994006 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 241944 241944 'Zfp267' mRNA 546 547.18 548.13 4.36 4.29 4.64 2.35 2.51 2.63 4.43 2.496666667 339.31 354.24 366.98 547.1033333 353.51 2.02E-07 -0.643867163 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 241950 241950 'Bbs12' mRNA 280 322 257 3.89 4.72 3.93 2.12 2.34 2.25 4.18 2.236666667 161 158 173 286.3333333 164 1.72E-06 -0.812559717 GO:0005929///cilium+++GO:0042995///cell projection GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0042073///intraciliary transport+++GO:0042755///eating behavior+++GO:0045494///photoreceptor cell maintenance+++GO:0045599///negative regulation of fat cell differentiation+++GO:0051131///chaperone-mediated protein complex assembly 241989 241989 'Pabpc4l' mRNA 61 78 66 0.61 0.78 0.7 0.66 0.65 0.6 0.696666667 0.636666667 76 74 67 68.33333333 72.33333333 0.863090843 0.071159245 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding GO:0008150///biological_process 242022 242022 'Frem2' mRNA 310.04 220.44 251.92 1.24 0.87 1.07 0.49 0.38 0.53 1.06 0.466666667 142.98 112.33 149.05 260.8 134.7866667 1.90E-06 -0.968190324 04512///ECM-receptor interaction GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001654///eye development+++GO:0001822///kidney development+++GO:0002009///morphogenesis of an epithelium+++GO:0007154///cell communication+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0042733///embryonic digit morphogenesis+++GO:0048839///inner ear development 242037 242037 'Ankub1' mRNA 1 4 1 0.03 0.13 0.03 0.29 0.35 0.15 0.063333333 0.263333333 10 12 5 2 9 0.080720754 2.172347448 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242050 242050 'Igsf10' mRNA 129 167.28 118.23 0.49 0.67 0.48 1.51 1.3 1.45 0.546666667 1.42 359.72 295.36 332.2 138.17 329.0933333 1.54E-12 1.243034598 GO:0005576///extracellular region GO:0003674///molecular_function GO:0001503///ossification+++GO:0042246///tissue regeneration+++GO:2001222///regulation of neuron migration 242083 242083 'Ppm1l' mRNA 2601 2656 2213 26.89 26.83 22.92 8.76 9.3 10.44 25.54666667 9.5 1060 1026 1175 2490 1087 2.36E-51 -1.204158343 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0006470///protein dephosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway 242109 242109 'Zfp697' mRNA 1076.11 1018.62 876.56 3.87 3.57 3.45 1.85 1.95 2.08 3.63 1.96 529.2 540.29 554 990.43 541.1633333 1.85E-18 -0.880209152 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 242122 242122 'Vtcn1' mRNA 17 8 13 0.36 0.3 0.39 0.43 0.77 0.53 0.35 0.576666667 17 22 25 12.66666667 21.33333333 0.289400668 0.739903629 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0005102///signaling receptor binding GO:0001562///response to protozoan+++GO:0001817///regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0032609///interferon-gamma production+++GO:0032633///interleukin-4 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0050852///T cell receptor signaling pathway+++GO:0050868///negative regulation of T cell activation 242125 242125 'Mab21l3' mRNA 17 10 8 0.31 0.16 0.13 0.32 0.13 0.07 0.2 0.173333333 21 8 5 11.66666667 11.33333333 0.960100778 -0.056547387 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242126 242126 'Slc22a15' mRNA 90 84 76.99 0.72 0.66 0.65 0.75 0.64 0.69 0.676666667 0.693333333 109 91 97 83.66333333 99 0.437864513 0.237329892 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0055085///transmembrane transport 242151 242151 'Kcna10' mRNA 9775 10021 10198 308 311.17 340.88 28.98 30.3 31.41 320.0166667 30.23 1057 1079 1109 9998 1081.666667 0 -3.221584224 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 242202 242202 'Pde5a' mRNA 701.03 668 589.01 5.8 5.37 4.95 3.5 3 3.14 5.373333333 3.213333333 494.41 424 446 652.68 454.8033333 3.52E-06 -0.53204251 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030553///cGMP binding+++GO:0046872///metal ion binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0002026///regulation of the force of heart contraction+++GO:0002678///positive regulation of chronic inflammatory response+++GO:0007165///signal transduction+++GO:0007614///short-term memory+++GO:0008152///metabolic process+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010749///regulation of nitric oxide mediated signal transduction+++GO:0042130///negative regulation of T cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045907///positive regulation of vasoconstriction+++GO:0046068///cGMP metabolic process+++GO:0046069///cGMP catabolic process+++GO:0055118///negative regulation of cardiac muscle contraction+++GO:0055119///relaxation of cardiac muscle+++GO:0060282///positive regulation of oocyte development 242235 242235 'Lrit3' mRNA 1 0 0 0.01 0 0 0 0.01 0.01 0.003333333 0.006666667 0 1 1 0.333333333 0.666666667 0.863090843 0.898150344 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0003674///molecular_function GO:0007601///visual perception+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0050896///response to stimulus 242248 242248 'Bank1' mRNA 7 13 12 0.14 0.3 0.21 0.49 0.39 0.46 0.216666667 0.446666667 28 26 28 10.66666667 27.33333333 0.026647055 1.343288884 GO:0005575///cellular_component+++GO:0048471///perinuclear region of cytoplasm GO:0002020///protease binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0035591///signaling adaptor activity+++GO:0043274///phospholipase binding+++GO:1990782///protein tyrosine kinase binding GO:0007165///signal transduction+++GO:0009617///response to bacterium+++GO:0032715///negative regulation of interleukin-6 production+++GO:0042113///B cell activation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045947///negative regulation of translational initiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050869///negative regulation of B cell activation+++GO:0051898///negative regulation of protein kinase B signaling 242253 242253 'Wdr63' mRNA 1056 1194 1117 19.21 21.39 21.54 2.18 1.72 1.59 20.71333333 1.83 138 106 97 1122.333333 113.6666667 1.61E-134 -3.317383595 GO:0005737///cytoplasm+++GO:0005858///axonemal dynein complex+++GO:0036156///inner dynein arm GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding+++GO:0071933///Arp2/3 complex binding GO:0007018///microtubule-based movement+++GO:0030336///negative regulation of cell migration+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0036159///inner dynein arm assembly+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0060294///cilium movement involved in cell motility 242259 242259 'Slc44a5' mRNA 10 10 13 0.12 0.09 0.12 0.03 0 0 0.11 0.01 3 0 0 11 1 0.01025355 -3.490951469 05231///Choline metabolism in cancer GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 242274 242274 'Lrrc7' mRNA 745.85 751.08 606.28 1.12 1.12 0.95 0.51 0.53 0.57 1.063333333 0.536666667 396.61 408.83 417.15 701.07 407.53 5.79E-12 -0.79119602 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0043005///neuron projection+++GO:0043194///axon initial segment+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0008022///protein C-terminus binding GO:0009790///embryo development+++GO:0010976///positive regulation of neuron projection development+++GO:0043113///receptor clustering+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion 242285 242285 'Sdr16c5' mRNA 50 74 65 2.17 3.17 2.99 5.94 4.77 4.73 2.776666667 5.146666667 157 123 121 63 133.6666667 7.01E-05 1.070809273 00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017053///transcriptional repressor complex "GO:0003714///transcription corepressor activity+++GO:0004745///retinol dehydrogenase activity+++GO:0008134///transcription factor binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0033613///activating transcription factor binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031065///positive regulation of histone deacetylation+++GO:0035067///negative regulation of histone acetylation+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:0043616///keratinocyte proliferation 242291 242291 'Bpnt2' mRNA 1553 1518 883 12.66 12.16 7.63 8.37 7.51 8.58 10.81666667 8.153333333 1182 1037 1174 1318 1131 0.43392793 -0.221325918 00920///Sulfur metabolism+++04070///Phosphatidylinositol signaling system GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0032588///trans-Golgi network membrane "GO:0008254///3'-nucleotidase activity+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0097657///3',5'-nucleotide bisphosphate phosphatase activity" GO:0001501///skeletal system development+++GO:0001958///endochondral ossification+++GO:0002063///chondrocyte development+++GO:0009791///post-embryonic development+++GO:0030204///chondroitin sulfate metabolic process+++GO:0042733///embryonic digit morphogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046855///inositol phosphate dephosphorylation 242297 242297 'Fam110b' mRNA 478 540 474 8.33 9.37 8.64 3.8 3.89 4.47 8.78 4.053333333 255 253 284 497.3333333 264 4.51E-12 -0.923980114 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 242316 242316 'Gdf6' mRNA 3 0 0 0.05 0 0 0.01 0 0.03 0.016666667 0.013333333 1 0 2 1 1 0.998696207 0.006328759 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0042802///identical protein binding+++GO:0048018///receptor ligand activity "GO:0001656///metanephros development+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0010631///epithelial cell migration+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030509///BMP signaling pathway+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0032924///activin receptor signaling pathway+++GO:0035788///cell migration involved in metanephros development+++GO:0045444///fat cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction+++GO:0072170///metanephric tubule development+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1990009///retinal cell apoptotic process" 242341 242341 'Atp6v0d2' mRNA 5 6 10 0.1 0.13 0.24 25.95 23.64 26.3 0.156666667 25.29666667 1342 1197 1318 7 1285.666667 4.25E-113 7.508744065 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++05323///Rheumatoid arthritis "GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0033181///plasma membrane proton-transporting V-type ATPase complex" "GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0007034///vacuolar transport+++GO:0007035///vacuolar acidification+++GO:1902600///proton transmembrane transport 242362 242362 'Manea' mRNA 630 663 663 7.19 7.42 8.02 6.87 5.74 6.11 7.543333333 6.24 689 567 594 652 616.6666667 0.496584731 -0.094890354 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004559///alpha-mannosidase activity+++GO:0004569///glycoprotein endo-alpha-1,2-mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" 242377 242377 'Pm20d2' mRNA 564 470 289 5.37 4.39 2.92 1.18 1.81 1.8 4.226666667 1.596666667 143 214 212 441 189.6666667 1.86E-08 -1.213941839 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0042802///identical protein binding+++GO:0071713///para-aminobenzoyl-glutamate hydrolase activity GO:0006508///proteolysis+++GO:0032268///regulation of cellular protein metabolic process+++GO:0046657///folic acid catabolic process 242384 242384 'Lingo2' mRNA 123 111 85 1.78 1.55 1.18 0.21 0.15 0.23 1.503333333 0.196666667 17 15 17 106.3333333 16.33333333 1.90E-14 -2.709188859 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0051965///positive regulation of synapse assembly 242406 242406 'Rgp1' mRNA 623.61 672.43 664.53 5.64 5.98 6.38 5.75 5 5.89 6 5.546666667 731.94 622.19 726.18 653.5233333 693.4366667 0.614783931 0.071936094 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding "GO:0042147///retrograde transport, endosome to Golgi+++GO:0043547///positive regulation of GTPase activity+++GO:1903363///negative regulation of cellular protein catabolic process" 242408 242408 'Fam221b' mRNA 28 39 33 0.92 1.26 1.15 0.06 0.09 0.03 1.11 0.06 2 3 1 33.33333333 2 5.84E-07 -4.069393386 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242409 242409 'Tmem8b' mRNA 273.38 280 262 2.99 2.89 3.01 1.62 1.57 1.36 2.963333333 1.516666667 171.87 169.65 138.83 271.7933333 160.1166667 8.24E-06 -0.781355204 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0040008///regulation of growth 242418 242418 'Dcaf10' mRNA 432.83 362.54 379.2 2.96 2.51 2.85 2.56 2.28 2.49 2.773333333 2.443333333 419.15 369.08 392.89 391.5233333 393.7066667 0.988052445 -0.004257546 GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 242425 242425 'Gabbr2' mRNA 2 0 0 0.02 0 0 0.05 0.05 0.08 0.006666667 0.06 6 6 9 0.666666667 7 0.045699708 3.392397104 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04727///GABAergic synapse+++04742///Taste transduction+++04915///Estrogen signaling pathway+++04929///GnRH secretion+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:1902710///GABA receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007214///gamma-aminobutyric acid signaling pathway 242443 242443 'Grin3a' mRNA 14 5 8 0.13 0.03 0.07 0.04 0.04 0.02 0.076666667 0.033333333 7 5 3 9 5 0.447246095 -0.863422927 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05034///Alcoholism GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0004970///ionotropic glutamate receptor activity+++GO:0004972///NMDA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0016594///glycine binding+++GO:0038023///signaling receptor activity+++GO:0042165///neurotransmitter binding+++GO:0042802///identical protein binding+++GO:0051721///protein phosphatase 2A binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0016358///dendrite development+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0045471///response to ethanol+++GO:0048511///rhythmic process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060134///prepulse inhibition+++GO:0061000///negative regulation of dendritic spine development+++GO:0070588///calcium ion transmembrane transport+++GO:2000300///regulation of synaptic vesicle exocytosis 242466 242466 'Zfp462' mRNA 1724.25 1597.99 1278.87 5.61 5.34 4.4 3.01 2.42 3.19 5.116666667 2.873333333 1077.48 821.53 1041.55 1533.703333 980.1866667 2.47E-09 -0.654694193 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0006325///chromatin organization+++GO:0010468///regulation of gene expression+++GO:0043392///negative regulation of DNA binding+++GO:0045944///positive regulation of transcription by RNA polymerase II 242474 242474 'Tmem245' mRNA 2159.95 2207.72 1916.31 7.59 7.6 6.72 6.01 5.08 5.9 7.303333333 5.663333333 2050.64 1664.09 1938.5 2094.66 1884.41 0.060712879 -0.163521426 GO:0016020///membrane+++GO:0016021///integral component of membrane 242484 242484 'D630039A03Rik' mRNA 325 310 295 6.18 5.8 5.95 2.84 2.96 2.2 5.976666667 2.666666667 172 175 129 310 158.6666667 2.37E-08 -0.977559184 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242505 242505 'Rasef' mRNA 849 896 810 8.26 8.57 8.42 4.44 4.37 4.68 8.416666667 4.496666667 523 505 533 851.6666667 520.3333333 4.02E-13 -0.721625987 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding 242506 242506 'Frmd3' mRNA 283 326 254 5.03 5.18 4.53 4.42 4.4 4.05 4.913333333 4.29 282 265 256 287.6666667 267.6666667 0.560419405 -0.112729716 GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008092///cytoskeletal protein binding GO:0031032///actomyosin structure organization 242509 242509 'Bnc2' mRNA 87 89 55 0.81 0.79 0.48 0.63 0.58 0.52 0.693333333 0.576666667 72 66 64 77 67.33333333 0.605516244 -0.197531195 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0003416///endochondral bone growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042981///regulation of apoptotic process+++GO:0043586///tongue development+++GO:0060021///roof of mouth development+++GO:0060485///mesenchyme development" 242521 242521 'Klhl9' mRNA 2503 2547 2572 31.95 31.98 34.83 32.93 33.43 32.1 32.92 32.82 2969 2945 2803 2540.666667 2905.666667 0.014253707 0.180625622 04120///Ubiquitin mediated proteolysis GO:0030496///midbody+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0097602///cullin family protein binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division 242523 242523 'Dmrta1' mRNA 336 364 369 4.45 4.74 5.18 1.98 2.12 1.96 4.79 2.02 172 180 165 356.3333333 172.3333333 2.11E-11 -1.061170627 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007281///germ cell development+++GO:0007548///sex differentiation+++GO:0060179///male mating behavior" 242546 242546 'Cyp2j12' mRNA 0 5 0 0 0.14 0 0.06 0.13 0.03 0.046666667 0.073333333 2 5 1 1.666666667 2.666666667 0.782456974 0.712370837 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 242553 242553 'Kank4' mRNA 588 618 372 6.34 6.42 4.35 3.99 4.62 4.15 5.703333333 4.253333333 418 476 425 526 439.6666667 0.137985301 -0.259283031 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0003674///molecular_function GO:0030837///negative regulation of actin filament polymerization+++GO:0051497///negative regulation of stress fiber assembly 242557 242557 'Atg4c' mRNA 666.36 657 678.98 11.73 11.58 12.84 7.58 8.39 9.15 12.05 8.373333333 500.11 551 579 667.4466667 543.37 0.011738912 -0.307859914 04136///Autophagy - other+++04140///Autophagy - animal GO:0005737///cytoplasm GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006914///autophagy+++GO:0015031///protein transport 242570 242570 'Raver2' mRNA 541.06 490.95 522.59 7.32 6.53 7.5 2.03 1.55 1.78 7.116666667 1.786666667 172.96 128.82 146.48 518.2 149.42 4.88E-33 -1.815029959 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome" 242574 242574 'C130073F10Rik' mRNA 2 1 0 0.14 0.07 0 0.19 0.32 0.06 0.07 0.19 3 5 1 1 3 0.468663623 1.598672721 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 242584 242584 'Wdr78' mRNA 715 838 703 10.93 12.38 11.24 1.75 2.18 1.83 11.51666667 1.92 135 148 141 752 141.3333333 1.38E-72 -2.420878605 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0070286///axonemal dynein complex assembly 242585 242585 'Slc35d1' mRNA 258.24 273.9 244.36 2.42 2.43 2.21 2.55 2.35 2.88 2.353333333 2.593333333 299 262.93 323.88 258.8333333 295.27 0.322368749 0.178790919 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005461///UDP-glucuronic acid transmembrane transporter activity+++GO:0005462///UDP-N-acetylglucosamine transmembrane transporter activity+++GO:0005463///UDP-N-acetylgalactosamine transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008643///carbohydrate transport+++GO:0015787///UDP-glucuronic acid transmembrane transport+++GO:0015789///UDP-N-acetylgalactosamine transmembrane transport+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0048706///embryonic skeletal system development+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:1990569///UDP-N-acetylglucosamine transmembrane transport 242594 242594 'Fyb2' mRNA 33 37 30 0.6 0.66 0.58 0.16 0.05 0.09 0.613333333 0.1 10 3 4 33.33333333 5.666666667 6.71E-05 -2.571766323 GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045121///membrane raft GO:0003674///molecular_function GO:0007229///integrin-mediated signaling pathway+++GO:0033627///cell adhesion mediated by integrin+++GO:0050852///T cell receptor signaling pathway+++GO:0072659///protein localization to plasma membrane 242602 242602 'Lexm' mRNA 1 1 1 0.03 0.03 0.03 0 0 0 0.03 0 0 0 0 1 0 0.568344116 -2.455252046 GO:0005739///mitochondrion GO:0005515///protein binding+++GO:0097177///mitochondrial ribosome binding GO:0008284///positive regulation of cell proliferation+++GO:1903862///positive regulation of oxidative phosphorylation 242603 242603 'Cdcp2' mRNA 2274 2268 2129 35.15 34.56 34.87 2.98 1.96 2.18 34.86 2.373333333 223 143 158 2223.666667 174.6666667 1.66E-231 -3.684005844 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 242607 242607 'Slc1a7' mRNA 0 1 1 0 0.02 0.02 0.04 0 0.02 0.013333333 0.02 2 0 1 0.666666667 1 0.875025628 0.546587239 04721///Synaptic vesicle cycle+++04724///Glutamatergic synapse GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015501///glutamate:sodium symporter activity GO:0001504///neurotransmitter uptake+++GO:0015813///L-glutamate transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098810///neurotransmitter reuptake 242608 242608 'Podn' mRNA 3 4 6 0.07 0.07 0.12 0.17 0.05 0.08 0.086666667 0.1 11 3 5 4.333333333 6.333333333 0.725064452 0.514287282 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005518///collagen binding GO:0008285///negative regulation of cell proliferation+++GO:0030336///negative regulation of cell migration 242620 242620 'Dmrta2' mRNA 6 8 2 0.12 0.16 0.04 0.02 0.02 0.04 0.106666667 0.026666667 1 1 2 5.333333333 1.333333333 0.213946259 -1.989335788 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007548///sex differentiation+++GO:0021796///cerebral cortex regionalization+++GO:0035914///skeletal muscle cell differentiation+++GO:0048665///neuron fate specification+++GO:0071542///dopaminergic neuron differentiation" 242627 242627 'Skint5' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 242642 242642 'Hpdl' mRNA 542 466 433 19.8 16.79 16.78 16.12 16.85 15.68 17.79 16.21666667 507 517 477 480.3333333 500.3333333 0.772358308 0.04932699 GO:0005575///cellular_component+++GO:0005739///mitochondrion "GO:0003868///4-hydroxyphenylpyruvate dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016701///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0009072///aromatic amino acid family metabolic process 242646 242646 'Tctex1d4' mRNA 1 3 0 0.07 0.2 0 0.71 0.92 0.32 0.09 0.65 12 15 6 1.333333333 11 0.016459167 3.053112586 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0008157///protein phosphatase 1 binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement 242653 242653 'Cldn19' mRNA 1135 1093 1032 46.42 46.26 47.08 35.94 34.54 34.76 46.58666667 35.08 1040 893 925 1086.666667 952.6666667 0.035410378 -0.202010095 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0048471///perinuclear region of cytoplasm GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0019227///neuronal action potential propagation+++GO:0030336///negative regulation of cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0043297///apical junction assembly+++GO:0061045///negative regulation of wound healing+++GO:0070830///bicellular tight junction assembly+++GO:0120193///tight junction organization+++GO:1901890///positive regulation of cell junction assembly 242662 242662 'Rims3' mRNA 261 235 183 2.14 1.88 1.62 0.33 0.34 0.27 1.88 0.313333333 47 46 36 226.3333333 43 1.18E-23 -2.402710369 GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0031267///small GTPase binding+++GO:0044325///ion channel binding GO:0006836///neurotransmitter transport+++GO:0006887///exocytosis+++GO:0017156///calcium ion regulated exocytosis+++GO:0042391///regulation of membrane potential+++GO:0048167///regulation of synaptic plasticity+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0050806///positive regulation of synaptic transmission+++GO:0050807///regulation of synapse organization+++GO:2000300///regulation of synaptic vesicle exocytosis 242667 242667 'Dlgap3' mRNA 6 6 7 0.08 0.11 0.14 0.04 0.08 0.06 0.11 0.06 3 5 3 6.333333333 3.666666667 0.5447461 -0.800874044 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0098981///cholinergic synapse+++GO:0099572///postsynaptic specialization GO:0001540///amyloid-beta binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0060090///molecular adaptor activity+++GO:0097110///scaffold protein binding GO:0023052///signaling+++GO:0065003///protein-containing complex assembly+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099563///modification of synaptic structure 242669 242669 'Azin2' mRNA 122 102 61 3.66 2.91 2.02 2.44 2.32 1.88 2.863333333 2.213333333 90 82 59 95 77 0.402414183 -0.30551813 00330///Arginine and proline metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:1990005///granular vesicle GO:0003824///catalytic activity+++GO:0004586///ornithine decarboxylase activity+++GO:0005515///protein binding+++GO:0008792///arginine decarboxylase activity+++GO:0042978///ornithine decarboxylase activator activity GO:0000278///mitotic cell cycle+++GO:0006591///ornithine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0033387///putrescine biosynthetic process from ornithine+++GO:0042110///T cell activation+++GO:0042177///negative regulation of protein catabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0044565///dendritic cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0097028///dendritic cell differentiation+++GO:0098629///trans-Golgi network membrane organization+++GO:1902269///positive regulation of polyamine transmembrane transport 242681 242681 'Rab42' mRNA 114.67 145.13 94.03 6.25 8.23 5.51 4.27 4.26 5.84 6.663333333 4.79 98.95 89.44 110.62 117.9433333 99.67 0.387468193 -0.254675905 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding 242687 242687 'Wasf2' mRNA 2471 2504 1668 26.65 26.78 18.3 29.16 26.61 27.5 23.91 27.75666667 3179 2897 2986 2214.333333 3020.666667 1.66E-05 0.44401583 04520///Adherens junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05135///Yersinia infection+++05231///Choline metabolism in cancer GO:0001726///ruffle+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0031209///SCAR complex+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051018///protein kinase A binding+++GO:0071933///Arp2/3 complex binding GO:0001525///angiogenesis+++GO:0001667///ameboidal-type cell migration+++GO:0006897///endocytosis+++GO:0006928///movement of cell or subcellular component+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016601///Rac protein signal transduction+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030048///actin filament-based movement+++GO:0035855///megakaryocyte development+++GO:0051497///negative regulation of stress fiber assembly+++GO:0072673///lamellipodium morphogenesis+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 242691 242691 'Gpatch3' mRNA 141 138 51 4.01 3.86 1.54 2.55 4.99 3.78 3.136666667 3.773333333 103 197 148 110 149.3333333 0.224373817 0.45356801 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0003676///nucleic acid binding "GO:0032480///negative regulation of type I interferon production+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated" 242700 242700 'Ifnlr1' mRNA 482 454 340 6.48 6.01 4.85 3.51 4.07 4.07 5.78 3.883333333 300 340 337 425.3333333 325.6666667 0.012786425 -0.38982065 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032002///interleukin-28 receptor complex GO:0004896///cytokine receptor activity GO:0002385///mucosal immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034342///response to type III interferon+++GO:0050691///regulation of defense response to virus by host+++GO:0051607///defense response to virus+++GO:1901857///positive regulation of cellular respiration 242702 242702 'Myom3' mRNA 19 14 18 0.25 0.18 0.25 0.16 0.12 0.08 0.226666667 0.12 14 10 7 17 10.33333333 0.340993653 -0.736785422 GO:0005737///cytoplasm+++GO:0031430///M band GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding GO:0006936///muscle contraction 242705 242705 'E2f2' mRNA 46 71 50 0.59 0.91 0.72 1.3 0.92 1.49 0.74 1.236666667 120 83 130 55.66666667 111 0.00130056 0.98541414 01522///Endocrine resistance+++04110///Cell cycle+++04218///Cellular senescence+++04934///Cushing syndrome+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1990086///lens fiber cell apoptotic process" 242707 242707 'Lactbl1' mRNA 0 0 2 0 0 0.02 0.01 0.01 0 0.006666667 0.006666667 1 1 0 0.666666667 0.666666667 0.992437553 -0.07674363 GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 242721 242721 'Klhdc7a' mRNA 854 789 562 7.75 7.04 5.41 7.56 6.95 7.09 6.733333333 7.2 959 862 872 735 897.6666667 0.029281535 0.282997533 GO:0016020///membrane+++GO:0016021///integral component of membrane 242726 242726 'Padi6' mRNA 1 0 0 0.02 0 0 0.02 0 0 0.006666667 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0045111///intermediate filament cytoskeleton+++GO:0060473///cortical granule GO:0004668///protein-arginine deiminase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity GO:0007010///cytoskeleton organization+++GO:0007028///cytoplasm organization+++GO:0018101///protein citrullination+++GO:0034613///cellular protein localization+++GO:0036414///histone citrullination+++GO:0040016///embryonic cleavage+++GO:0043143///regulation of translation by machinery localization 242735 242735 'Lrrc38' mRNA 30 20 23 0.72 0.47 0.59 0.27 0.3 0.17 0.593333333 0.246666667 13 14 8 24.33333333 11.66666667 0.092575729 -1.072518986 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0099104///potassium channel activator activity GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity 242736 242736 'Pramel12' mRNA 657 756 714 9.15 10.42 10.65 7.05 7.75 6.67 10.07333333 7.156666667 579 620 530 709 576.3333333 0.010543617 -0.310753715 GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 242747 242747 'Zfp933' mRNA 357.55 327.13 352.95 3.82 3.35 4.01 3.05 2.64 2.49 3.726666667 2.726666667 341.18 274.57 263.06 345.8766667 292.9366667 0.134212985 -0.254099778 05168///Herpes simplex virus 1 infection GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 242748 242748 'Disp3' mRNA 34 28 41 0.21 0.17 0.28 0.04 0.02 0.03 0.22 0.03 6 4 2 34.33333333 4 4.62E-06 -3.124203575 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane GO:0003674///molecular_function GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0030154///cell differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045834///positive regulation of lipid metabolic process+++GO:2000179///positive regulation of neural precursor cell proliferation 242773 242773 'Slc45a1' mRNA 1 0 0 0.02 0 0 0.03 0.01 0.11 0.006666667 0.05 2 1 8 0.333333333 3.666666667 0.14501886 3.345215561 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005355///glucose transmembrane transporter activity+++GO:0008506///sucrose:proton symporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0015770///sucrose transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 242785 242785 'Klhl21' mRNA 1346 1710 1574 18.68 23.34 23.17 16.84 15.22 15.92 21.73 15.99333333 1397 1233 1279 1543.333333 1303 0.013168446 -0.257884231 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005827///polar microtubule+++GO:0005856///cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0097602///cullin family protein binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0032465///regulation of cytokinesis+++GO:0035853///chromosome passenger complex localization to spindle midzone+++GO:0051301///cell division 242800 242800 'Ttc34' mRNA 533 632 208 6.02 7.05 2.52 0.23 0.33 0.35 5.196666667 0.303333333 24 33 35 457.6666667 30.66666667 8.90E-15 -3.886366384 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242805 242805 'Ankrd65' mRNA 2.98 2 4.06 0.12 0.08 0.18 0.11 0.26 0.06 0.126666667 0.143333333 2.94 6 1.48 3.013333333 3.473333333 0.938641229 0.151323656 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242819 242819 'Rundc3b' mRNA 19 20 21 0.26 0.29 0.34 0.17 0.22 0.1 0.296666667 0.163333333 13 17 7 20 12.33333333 0.323525529 -0.710062147 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 242838 242838 'Lrrd1' mRNA 3 1 1 0.06 0.02 0.02 0.03 0.03 0.02 0.033333333 0.026666667 2 2 1 1.666666667 1.666666667 0.998591786 -0.004711887 GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0046579///positive regulation of Ras protein signal transduction 242860 242860 'Rsbn1l' mRNA 358 407 338 3.43 3.83 3.43 2.75 2.61 3.01 3.563333333 2.79 330 306 350 367.6666667 328.6666667 0.285438192 -0.171481095 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0008150///biological_process 242864 242864 'Napepld' mRNA 198 172 182 2.78 2.38 2.71 3.47 2.96 3.23 2.623333333 3.22 285 237 254 184 258.6666667 0.007651776 0.477630193 04723///Retrograde endocannabinoid signaling GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043227///membrane-bounded organelle GO:0004620///phospholipase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0032052///bile acid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070290///N-acylphosphatidylethanolamine-specific phospholipase D activity+++GO:0102200///N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity GO:0001659///temperature homeostasis+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0007568///aging+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0035900///response to isolation stress+++GO:0048874///host-mediated regulation of intestinal microbiota composition+++GO:0050729///positive regulation of inflammatory response+++GO:0070291///N-acylethanolamine metabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:1903999///negative regulation of eating behavior 242891 242891 'Cct8l1' mRNA 3 0 0 0.09 0 0 0.08 0 0.1 0.03 0.06 3 0 4 1 2.333333333 0.674221909 1.222634998 GO:0005832///chaperonin-containing T-complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0051082///unfolded protein binding GO:0006457///protein folding 242894 242894 'Actr3b' mRNA 419 420 376 11.36 11.29 10.86 6.87 5.55 5.91 11.17 6.11 289 228 239 405 252 1.61E-06 -0.696430018 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0008150///biological_process 242915 242915 'Garem2' mRNA 2 7 2 0.03 0.1 0.03 0.01 0.05 0.05 0.053333333 0.036666667 1 4 4 3.666666667 3 0.874344538 -0.2754536 GO:0003674///molecular_function GO:0008150///biological_process 242939 242939 'Cpz' mRNA 70 71 89 1.82 1.82 2.45 3.7 3.63 3.85 2.03 3.726666667 164 157 165 76.66666667 162 7.57E-06 1.062627884 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016485///protein processing 242960 242960 'Fbxl5' mRNA 2229 2498 2456 41.15 45.18 47.72 38.8 35.62 38.28 44.68333333 37.56666667 2402 2160 2310 2394.333333 2290.666667 0.409678779 -0.077873428 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm GO:0005506///iron ion binding+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0055072///iron ion homeostasis+++GO:1903364///positive regulation of cellular protein catabolic process 243025 243025 'Tmem156' mRNA 6 5 12 0.1 0.08 0.39 0.8 0.86 0.39 0.19 0.683333333 46 53 26 7.666666667 41.66666667 4.49E-05 2.418325315 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0030414///peptidase inhibitor activity GO:0007155///cell adhesion+++GO:0008150///biological_process+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030198///extracellular matrix organization 243043 243043 'Kctd8' mRNA 8 2 5 0.15 0.04 0.1 0 0 0 0.096666667 0 0 0 0 5 0 0.019459748 -4.78098625 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0003674///molecular_function GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0051260///protein homooligomerization 243078 243078 'Tecrl' mRNA 4 4 0 0.09 0.09 0 0.02 0.08 0.23 0.06 0.11 1 4 11 2.666666667 5.333333333 0.555722717 1.025576359 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors" GO:0006629///lipid metabolic process+++GO:0042761///very long-chain fatty acid biosynthetic process 243197 243197 'Mfsd7a' mRNA 96 108 94 1.67 1.56 1.81 1.95 2.15 1.91 1.68 2.003333333 127 122 122 99.33333333 123.6666667 0.240779294 0.305507195 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 243219 243219 '2900026A02Rik' mRNA 1606 1616 1518 11.92 11.77 12.57 8.99 7.19 8.01 12.08666667 8.063333333 1344 1083 1179 1580 1202 2.81E-06 -0.407443498 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 243262 243262 'Oas1f' mRNA 1 0 0 0.04 0 0 0 0.04 0 0.013333333 0.013333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0016779///nucleotidyltransferase activity GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 243270 243270 'Hcar1' mRNA 3 10 4 0.05 0.16 0.07 0.15 0.06 0.14 0.093333333 0.116666667 10 4 9 5.666666667 7.666666667 0.748070175 0.430158709 04024///cAMP signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043229///intracellular organelle GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050995///negative regulation of lipid catabolic process 243272 243272 'Sbno1' mRNA 2044 1993 2015 11.13 10.5 11.59 10.43 10.3 10.57 11.07333333 10.43333333 2174 2093 2151 2017.333333 2139.333333 0.398932495 0.071954006 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0031490///chromatin DNA binding+++GO:0042393///histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 243277 243277 'Adgrd1' mRNA 1246 1290 1258 13.13 13.37 14.06 0.64 0.95 0.83 13.52 0.806666667 70 101 88 1264.666667 86.33333333 9.48E-177 -3.883683232 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 243300 243300 'Nyap1' mRNA 136 122 108 2.1 1.86 1.81 1.96 1.37 1.64 1.923333333 1.656666667 145 99 118 122 120.6666667 0.930111544 -0.027880548 GO:0005515///protein binding GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0048812///neuron projection morphogenesis 243302 243302 'Gm4963' mRNA 0.98 2.22 0 0.18 0.41 0 0.34 0 0 0.196666667 0.113333333 2.09 0 0 1.066666667 0.696666667 0.999712891 0.001695352 243308 243308 'A430033K04Rik' mRNA 566.44 586.28 591.87 9.83 10.01 10.9 5.71 5.07 5.76 10.24666667 5.513333333 378.38 328.08 369.47 581.53 358.6433333 7.45E-09 -0.711063906 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 243312 243312 'Elfn1' mRNA 1526 1598 783 21.01 21.6 11.4 1.1 1.39 1.45 18.00333333 1.313333333 93 113 117 1302.333333 107.6666667 3.39E-29 -3.590762542 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0042995///cell projection+++GO:0060076///excitatory synapse GO:0004864///protein phosphatase inhibitor activity GO:0010923///negative regulation of phosphatase activity+++GO:0043086///negative regulation of catalytic activity+++GO:0050808///synapse organization 243328 243328 'Slc29a4' mRNA 30 18 17 0.6 0.36 0.37 0.36 0.32 0.13 0.443333333 0.27 20 18 7 21.66666667 15 0.467488175 -0.539901267 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098793///presynapse GO:0005326///neurotransmitter transporter activity+++GO:0005337///nucleoside transmembrane transporter activity+++GO:0005342///organic acid transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity+++GO:0008504///monoamine transmembrane transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity GO:0006836///neurotransmitter transport+++GO:0015695///organic cation transport+++GO:0015844///monoamine transport+++GO:0042908///xenobiotic transport+++GO:0051610///serotonin uptake+++GO:0051615///histamine uptake+++GO:0051620///norepinephrine uptake+++GO:0051625///epinephrine uptake+++GO:0055085///transmembrane transport+++GO:0090494///dopamine uptake+++GO:0098655///cation transmembrane transport+++GO:0140115///export across plasma membrane+++GO:1901642///nucleoside transmembrane transport+++GO:1901998///toxin transport+++GO:1903825///organic acid transmembrane transport 243339 243339 'Tmem130' mRNA 694 661 606 14.04 13.16 13 0.98 1.19 1.09 13.4 1.086666667 56 66 60 653.6666667 60.66666667 4.54E-99 -3.439195496 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 243362 243362 'Stard13' mRNA 1439.02 1300 1512 7.87 6.94 9.07 6.64 6.39 6.87 7.96 6.633333333 1374.73 1179 1328 1417.006667 1293.91 0.187072474 -0.147891928 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008289///lipid binding GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043542///endothelial cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060055///angiogenesis involved in wound healing+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0097498///endothelial tube lumen extension+++GO:1903671///negative regulation of sprouting angiogenesis 243369 243369 'Sspo' mRNA 23 41 34 0.07 0.13 0.13 0.06 0.07 0.06 0.11 0.063333333 24 24 23 32.66666667 23.66666667 0.388089417 -0.477073086 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030414///peptidase inhibitor activity GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0008150///biological_process+++GO:0030154///cell differentiation+++GO:0043086///negative regulation of catalytic activity+++GO:0052547///regulation of peptidase activity 243371 243371 'Lrrc61' mRNA 807.93 875.92 864.01 15.68 16.74 17.73 10.21 8.55 8.81 16.71666667 9.19 599.46 491.35 505.64 849.2866667 532.15 5.82E-10 -0.689274707 GO:0005737///cytoplasm+++GO:0005829///cytosol 243372 243372 'Zfp775' mRNA 292 356 346 6.45 7.74 8.08 3.87 3.36 3.59 7.423333333 3.606666667 202 171 181 331.3333333 184.6666667 2.90E-07 -0.857978919 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 243374 243374 'Gimap8' mRNA 33.15 33.61 29.81 0.5 0.57 0.51 0.49 0.54 0.67 0.526666667 0.566666667 37.82 36.36 50.36 32.19 41.51333333 0.457835686 0.363434415 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0070232///regulation of T cell apoptotic process 243382 243382 'Ppm1k' mRNA 533.83 563.3 455.13 5.07 5.26 4.58 4.1 3.73 4.12 4.97 3.983333333 497.68 442.14 485.12 517.42 474.98 0.343893384 -0.132361606 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation 243385 243385 'Gprin3' mRNA 1018.21 1057.9 932.51 10.16 10.19 10.39 7.34 5.54 6.43 10.24666667 6.436666667 942.22 656.82 811.07 1002.873333 803.37 0.005354657 -0.33280524 GO:0005886///plasma membrane GO:0003674///molecular_function GO:0031175///neuron projection development 243407 243407 'Qrfprl' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 243499 243499 'Lrrtm4' mRNA 367.38 412.6 314.59 3.81 4.39 3.6 1.94 1.59 1.93 3.933333333 1.82 207.72 165.38 195.52 364.8566667 189.54 2.19E-09 -0.955776558 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0043395///heparan sulfate proteoglycan binding GO:0050808///synapse organization+++GO:0051963///regulation of synapse assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0072578///neurotransmitter-gated ion channel clustering+++GO:0097113///AMPA glutamate receptor clustering+++GO:1901629///regulation of presynaptic membrane organization 243510 243510 'Ccdc142' mRNA 230 232 231 4.03 4 4.29 2.59 2.4 2.81 4.106666667 2.6 170 154 179 231 167.6666667 0.009973505 -0.475085693 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 243529 243529 'H1f10' mRNA 23 9 6 1.37 0.53 0.38 0.21 0.37 0.48 0.76 0.353333333 4 7 9 12.66666667 6.666666667 0.354668686 -0.919859348 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0031492///nucleosomal DNA binding GO:0006334///nucleosome assembly+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination 243537 243537 'Uroc1' mRNA 0 3 2 0 0.05 0.04 0 0 0.04 0.03 0.013333333 0 0 1 1.666666667 0.333333333 0.498459769 -2.231852623 00340///Histidine metabolism GO:0005829///cytosol GO:0016153///urocanate hydratase activity+++GO:0016829///lyase activity GO:0006547///histidine metabolic process+++GO:0006548///histidine catabolic process+++GO:0019556///histidine catabolic process to glutamate and formamide+++GO:0019557///histidine catabolic process to glutamate and formate 243538 243538 'Cfap100' mRNA 114 102 78 2.03 1.92 1.32 1.46 1.51 1.48 1.756666667 1.483333333 102 93 82 98 92.33333333 0.79630152 -0.093214099 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097545///axonemal outer doublet GO:0003674///molecular_function+++GO:0070840///dynein complex binding GO:0003341///cilium movement+++GO:0008150///biological_process+++GO:0036159///inner dynein arm assembly+++GO:2000574///regulation of microtubule motor activity 243547 243547 'Grip2' mRNA 2 5 6 0.02 0.05 0.07 0.05 0.05 0.02 0.046666667 0.04 6 5 2 4.333333333 4.333333333 0.994417885 -0.02516123 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043198///dendritic shaft+++GO:0044309///neuron spine+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0035254///glutamate receptor binding "GO:0007219///Notch signaling pathway+++GO:0014042///positive regulation of neuron maturation+++GO:0014824///artery smooth muscle contraction+++GO:0015031///protein transport+++GO:0045777///positive regulation of blood pressure+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:1904719///positive regulation of AMPA glutamate receptor clustering+++GO:2000463///positive regulation of excitatory postsynaptic potential" 243548 243548 'Prickle2' mRNA 1162 1114 1103 7.38 6.94 7.4 2.62 2.79 2.5 7.24 2.636666667 474 487 440 1126.333333 467 3.30E-39 -1.281977626 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0001825///blastocyst formation+++GO:0001830///trophectodermal cell fate commitment+++GO:0030010///establishment of cell polarity+++GO:0031175///neuron projection development+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity 243574 243574 'Kbtbd8' mRNA 84 115 88 0.96 1.32 1.06 0.86 0.69 0.54 1.113333333 0.696666667 86 66 53 95.66666667 68.33333333 0.118823024 -0.497063255 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0006417///regulation of translation+++GO:0006513///protein monoubiquitination+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development 243612 243612 'Ssu2' mRNA 1 1 1 0.05 0.05 0.04 0.05 0.12 0 0.046666667 0.056666667 1 3 0 1 1.333333333 0.885604162 0.411653052 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0031072///heat shock protein binding+++GO:0051082///unfolded protein binding GO:0042476///odontogenesis 243616 243616 'Slc6a11' mRNA 4 8 5 0.05 0.1 0.07 0.01 0.12 0.04 0.073333333 0.056666667 1 10 3 5.666666667 4.666666667 0.863090843 -0.2728596 04721///Synaptic vesicle cycle+++04727///GABAergic synapse GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005332///gamma-aminobutyric acid:sodium symporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0042165///neurotransmitter binding GO:0001504///neurotransmitter uptake+++GO:0006836///neurotransmitter transport+++GO:0007420///brain development+++GO:0015718///monocarboxylic acid transport+++GO:0015812///gamma-aminobutyric acid transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042493///response to drug+++GO:0055085///transmembrane transport+++GO:0098810///neurotransmitter reuptake 243621 243621 'Iqsec3' mRNA 4 2 5 0.03 0.02 0.03 0.03 0.01 0 0.026666667 0.013333333 4 1 0 3.666666667 1.666666667 0.54901389 -1.178254576 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0098690///glycinergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099629///postsynaptic specialization of symmetric synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0030036///actin cytoskeleton organization+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0050808///synapse organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity 243634 243634 'Ano2' mRNA 162 158 121 2.34 2.24 1.87 0.14 0.01 0.1 2.15 0.083333333 11 1 8 147 6.666666667 3.02E-25 -4.472822318 04740///Olfactory transduction GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex+++GO:0097730///non-motile cilium GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0017128///phospholipid scramblase activity+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport 243653 243653 'Clec1a' mRNA 22 9 12 0.37 0.15 0.21 0.54 0.61 0.53 0.243333333 0.56 37 41 35 14.33333333 37.66666667 0.009607376 1.384791248 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0008150///biological_process 243655 243655 'Klre1' mRNA 1 1 1 0.05 0.07 0.06 0.58 0.41 0.42 0.06 0.47 10 6 7 1 7.666666667 0.042100018 2.922574833 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002859///negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0030101///natural killer cell activation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 243659 243659 'Styk1' mRNA 2 5 0 0.04 0.09 0 0.15 0.09 0.15 0.043333333 0.13 10 6 10 2.333333333 8.666666667 0.136766095 1.904391443 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0045087///innate immune response 243725 243725 'Ppp1r9a' mRNA 1806.84 1778.79 1484.05 8.9 8.65 7.79 4.24 3.66 4.09 8.446666667 3.996666667 1007.13 861.65 933.01 1689.893333 933.93 6.00E-24 -0.864928674 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031594///neuromuscular junction+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044326///dendritic spine neck+++GO:0045202///synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:1990761///growth cone lamellipodium GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0051020///GTPase binding GO:0007015///actin filament organization+++GO:0007399///nervous system development+++GO:0010976///positive regulation of neuron projection development+++GO:0019722///calcium-mediated signaling+++GO:0030833///regulation of actin filament polymerization+++GO:0031175///neuron projection development+++GO:0045860///positive regulation of protein kinase activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051489///regulation of filopodium assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051823///regulation of synapse structural plasticity+++GO:0051963///regulation of synapse assembly+++GO:0060079///excitatory postsynaptic potential+++GO:0060999///positive regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0097237///cellular response to toxic substance+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1904049///negative regulation of spontaneous neurotransmitter secretion 243743 243743 'Plxna4' mRNA 2334 2331 2121 9.66 9.48 9.31 1.39 1.18 1.38 9.483333333 1.316666667 387 322 372 2262 360.3333333 2.60E-205 -2.661543326 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0008045///motor neuron axon guidance+++GO:0008360///regulation of cell shape+++GO:0021602///cranial nerve morphogenesis+++GO:0021610///facial nerve morphogenesis+++GO:0021612///facial nerve structural organization+++GO:0021615///glossopharyngeal nerve morphogenesis+++GO:0021636///trigeminal nerve morphogenesis+++GO:0021637///trigeminal nerve structural organization+++GO:0021644///vagus nerve morphogenesis+++GO:0021784///postganglionic parasympathetic fiber development+++GO:0021785///branchiomotor neuron axon guidance+++GO:0021793///chemorepulsion of branchiomotor axon+++GO:0021960///anterior commissure morphogenesis+++GO:0030334///regulation of cell migration+++GO:0035050///embryonic heart tube development+++GO:0043087///regulation of GTPase activity+++GO:0048485///sympathetic nervous system development+++GO:0048812///neuron projection morphogenesis+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0050772///positive regulation of axonogenesis+++GO:0050923///regulation of negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0097492///sympathetic neuron axon guidance+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 243753 243753 'Slc23a4' mRNA 16 15 15 0.38 0.31 0.34 0.13 0.16 0.28 0.343333333 0.19 6 7 15 15.33333333 9.333333333 0.386928419 -0.725654751 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity GO:0008150///biological_process+++GO:0055085///transmembrane transport 243755 243755 'Slc13a4' mRNA 4091 4281 4431 65.02 66.94 74.71 94.26 93.24 93.36 68.89 93.62 6825 6594 6546 4267.666667 6655 1.83E-21 0.626766419 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport 243764 243764 'Chrm2' mRNA 6 2 1 0.14 0.05 0.01 0.04 0.05 0.1 0.066666667 0.063333333 5 3 4 3 4 0.823550341 0.414872009 04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04725///Cholinergic synapse+++04810///Regulation of actin cytoskeleton GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0032280///symmetric synapse+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098981///cholinergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:1990763///arrestin family protein binding "GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0008016///regulation of heart contraction+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:2000300///regulation of synaptic vesicle exocytosis" 243771 243771 'Parp12' mRNA 679 712 275 11.49 11.86 4.94 7.93 8.69 11.8 9.43 9.473333333 539 577 777 555.3333333 631 0.74668072 0.193846178 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:1990404///protein ADP-ribosylase activity GO:0006471///protein ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation 243780 243780 'Dennd11' mRNA 699.67 681.77 332.8 5.49 5.25 2.77 2.01 2.07 2.03 4.503333333 2.036666667 294.47 296.33 288.73 571.4133333 293.1766667 1.42E-06 -0.960053719 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 243813 243813 'Leng9' mRNA 214 206 212 7.36 6.98 7.73 5.92 6.84 7.57 7.356666667 6.776666667 198 223 245 210.6666667 222 0.794855205 0.064252317 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding 243816 243816 'Gp6' mRNA 5.81 5.6 6.97 0.04 0.04 0.1 0.01 0.07 0.05 0.06 0.043333333 2.19 10.07 6.77 6.126666667 6.343333333 0.903250008 0.164328256 04512///ECM-receptor interaction+++04611///Platelet activation GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0097197///tetraspanin-enriched microdomain GO:0005518///collagen binding+++GO:0038064///collagen receptor activity+++GO:1990782///protein tyrosine kinase binding GO:0001944///vasculature development+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0038065///collagen-activated signaling pathway 243819 243819 'Ppp6r1' mRNA 75 80 86 1.07 1.12 1.3 1.98 1.43 1.81 1.163333333 1.74 160 113 141 80.33333333 138 0.002724258 0.763886622 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019888///protein phosphatase regulator activity+++GO:0019903///protein phosphatase binding+++GO:0031267///small GTPase binding GO:0043666///regulation of phosphoprotein phosphatase activity 243833 243833 'Zfp128' mRNA 184 208 189 2.6 2.89 2.83 1.53 1.59 1.49 2.773333333 1.536666667 125 127 118 193.6666667 123.3333333 9.71E-04 -0.662204439 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030509///BMP signaling pathway" 243834 243834 'Zfp324' mRNA 425 415 407 5.34 5.09 5.4 3.19 2.66 2.19 5.276666667 2.68 295 241 196 415.6666667 244 1.07E-06 -0.782652222 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 243842 243842 'Bicra' mRNA 1253 1198 899 7.56 7.74 5.45 6.45 6.75 6.36 6.916666667 6.52 1299 1326 1239 1116.666667 1288 0.07051267 0.20036632 GO:0005634///nucleus+++GO:0016514///SWI/SNF complex "GO:0045893///positive regulation of transcription, DNA-templated" 243846 243846 'Ccdc9' mRNA 122.11 97.24 106.49 2.77 2.24 3.02 3.36 2.59 3.58 2.676666667 3.176666667 144.81 103.74 147.03 108.6133333 131.86 0.351936314 0.263388544 GO:0005575///cellular_component GO:0008150///biological_process 243853 243853 'Fkrp' mRNA 692 732 618 13.58 14.1 12.86 12.83 12.67 12.85 13.51333333 12.78333333 753 727 730 680.6666667 736.6666667 0.37600983 0.104580023 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0002162///dystroglycan binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006486///protein glycosylation+++GO:0009101///glycoprotein biosynthetic process+++GO:0016485///protein processing+++GO:0035269///protein O-linked mannosylation 243862 243862 'Psg22' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0045545///syndecan binding GO:0001525///angiogenesis+++GO:0001819///positive regulation of cytokine production+++GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0045766///positive regulation of angiogenesis+++GO:0071636///positive regulation of transforming growth factor beta production 243864 243864 'Mill2' mRNA 118.07 87.18 92.77 2.42 1.7 1.91 2.73 2.12 1.72 2.01 2.19 124.37 86.04 95.39 99.34 101.9333333 0.946310148 0.024273703 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding GO:0002429///immune response-activating cell surface receptor signaling pathway+++GO:0006955///immune response+++GO:0006979///response to oxidative stress+++GO:0009408///response to heat+++GO:0032526///response to retinoic acid+++GO:0046629///gamma-delta T cell activation+++GO:0050689///negative regulation of defense response to virus by host 243866 243866 'Meiosin' mRNA 5.12 5.24 5.06 0.08 0.11 0.11 0.23 0.18 0.35 0.1 0.253333333 14.37 10.14 20 5.14 14.83666667 0.075300849 1.53959463 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:0071300///cellular response to retinoic acid+++GO:0090427///activation of meiosis 243867 243867 'Fbxo46' mRNA 720 711 705 13.3 12.91 13.85 7.37 6.77 7.38 13.35333333 7.173333333 459 410 444 712 437.6666667 6.55E-11 -0.71492908 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 243874 243874 'Nlrp9b' mRNA 0 1 0 0 0.02 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005737///cytoplasm+++GO:0061702///inflammasome complex GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0032741///positive regulation of interleukin-18 production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0070269///pyroptosis 243881 243881 'Cyp2b23' mRNA 0 2 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00830///Retinol metabolism+++05207///Chemical carcinogenesis - receptor activation GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process+++GO:0017144///drug metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042178///xenobiotic catabolic process+++GO:0042180///cellular ketone metabolic process+++GO:0042738///exogenous drug catabolic process 243897 243897 'Ggn' mRNA 29 18 13 0.73 0.39 0.36 0.66 0.7 0.57 0.493333333 0.643333333 29 33 27 20 29.66666667 0.338041179 0.56632456 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding GO:0006302///double-strand break repair+++GO:0007275///multicellular organism development+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0007566///embryo implantation+++GO:0008104///protein localization+++GO:0030154///cell differentiation+++GO:0065003///protein-containing complex assembly 243905 243905 'Zfp568' mRNA 150 118 136 1.1 0.85 1.06 1.4 1.45 1.18 1.003333333 1.343333333 220 222 179 134.6666667 207 0.003852147 0.606812646 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0010646///regulation of cell communication+++GO:0022007///convergent extension involved in neural plate elongation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060028///convergent extension involved in axis elongation+++GO:0060669///embryonic placenta morphogenesis" 243906 243906 'Zfp14' mRNA 396.63 381.71 377.56 4.48 4.61 4.93 2.26 2.16 2.17 4.673333333 2.196666667 261.33 245.66 251.69 385.3 252.8933333 1.17E-05 -0.620544814 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0001835///blastocyst hatching+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 243910 243910 'Nfkbid' mRNA 50 36 40 1.39 0.98 1.2 2.88 2.44 3.24 1.19 2.853333333 118 98 129 42 115 9.70E-07 1.440644345 GO:0005634///nucleus GO:0005515///protein binding+++GO:0051059///NF-kappaB binding GO:0006954///inflammatory response+++GO:0010468///regulation of gene expression+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:2000321///positive regulation of T-helper 17 cell differentiation 243912 243912 'Hspb6' mRNA 656 670 668 29.13 29.56 31.62 27.25 26.4 29.22 30.10333333 27.62333333 702 660 728 664.6666667 696.6666667 0.695622188 0.055090414 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0005212///structural constituent of eye lens+++GO:0042803///protein homodimerization activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006937///regulation of muscle contraction+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0061077///chaperone-mediated protein folding 243914 243914 'Lgi4' mRNA 1009.85 1038.04 958.62 15.71 16.33 16.16 8.99 7.63 7.67 16.06666667 8.096666667 665.46 583.59 563.08 1002.17 604.0433333 2.25E-14 -0.742658272 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding GO:0008344///adult locomotory behavior+++GO:0014009///glial cell proliferation+++GO:0014044///Schwann cell development+++GO:0021782///glial cell development+++GO:0022011///myelination in peripheral nervous system+++GO:0031641///regulation of myelination+++GO:0042063///gliogenesis+++GO:0042551///neuron maturation+++GO:0042552///myelination 243923 243923 'Rgs9bp' mRNA 3 2 9 0.02 0.02 0.08 0.01 0.04 0 0.04 0.016666667 1 5 0 4.666666667 2 0.488679036 -1.255528043 GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0009968///negative regulation of signal transduction+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception 243931 243931 'Tshz3' mRNA 340.74 335.91 337.85 1.28 1.3 1.37 0.52 0.55 0.62 1.316666667 0.563333333 237.48 207.76 263.62 338.1666667 236.2866667 8.84E-04 -0.530426373 04391///Hippo signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0030426///growth cone+++GO:0042995///cell projection "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0001701///in utero embryonic development+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030324///lung development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048745///smooth muscle tissue development+++GO:0050881///musculoskeletal movement+++GO:0050975///sensory perception of touch+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0060993///kidney morphogenesis+++GO:0072105///ureteric peristalsis+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0072195///kidney smooth muscle cell differentiation" 243937 243937 'Zfp536' mRNA 869 1045 851 8.49 10.27 8.94 5.25 5.2 4.83 9.233333333 5.093333333 633 604 531 921.6666667 589.3333333 2.60E-09 -0.65502108 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045665///negative regulation of neuron differentiation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway" 243961 243961 'Shank1' mRNA 159 149 137 1.14 0.99 1.02 0.45 0.28 0.36 1.05 0.363333333 72 42 58 148.3333333 57.33333333 1.17E-07 -1.384931805 04724///Glutamatergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0017124///SH3 domain binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030160///GKAP/Homer scaffold activity+++GO:0031877///somatostatin receptor binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0071532///ankyrin repeat binding+++GO:0097110///scaffold protein binding+++GO:0098919///structural constituent of postsynaptic density "GO:0007399///nervous system development+++GO:0007616///long-term memory+++GO:0008306///associative learning+++GO:0030154///cell differentiation+++GO:0030534///adult behavior+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0035176///social behavior+++GO:0035418///protein localization to synapse+++GO:0042048///olfactory behavior+++GO:0046959///habituation+++GO:0048854///brain morphogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0050894///determination of affect+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060013///righting reflex+++GO:0060074///synapse maturation+++GO:0060291///long-term synaptic potentiation+++GO:0060997///dendritic spine morphogenesis+++GO:0060999///positive regulation of dendritic spine development+++GO:0065003///protein-containing complex assembly+++GO:0071625///vocalization behavior+++GO:0097107///postsynaptic density assembly+++GO:0099173///postsynapse organization+++GO:0099562///maintenance of postsynaptic density structure+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential" 243963 243963 'Zfp473' mRNA 11 27 11 0.16 0.37 0.18 0.21 0.24 0.04 0.236666667 0.163333333 16 19 3 16.33333333 12.66666667 0.721170071 -0.365502217 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015030///Cajal body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0045944///positive regulation of transcription by RNA polymerase II" 243967 243967 'Ntn5' mRNA 61 74.11 60 1.87 2.1 1.84 1.46 1.56 2.38 1.936666667 1.8 58 59.54 89 65.03666667 68.84666667 0.863090843 0.070878912 GO:0005576///extracellular region+++GO:0005604///basement membrane GO:0005102///signaling receptor binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008045///motor neuron axon guidance+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016358///dendrite development+++GO:0022008///neurogenesis 243978 243978 'Mrgprx2' mRNA 2 0 2 0.02 0 0.02 0 0 0 0.013333333 0 0 0 0 1.333333333 0 0.468848267 -2.893033412 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding+++GO:1990595///mast cell secretagogue receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0043303///mast cell degranulation+++GO:0045576///mast cell activation 243979 243979 'Mrgprb2' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0043303///mast cell degranulation+++GO:0045576///mast cell activation+++GO:1902349///response to chloroquine 243983 243983 'Zdhhc13' mRNA 768 788 849 17.86 18.12 20.96 10.1 11.84 9.84 18.98 10.59333333 500 571 471 801.6666667 514 7.95E-08 -0.654832426 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0031410///cytoplasmic vesicle "GO:0005515///protein binding+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0018345///protein palmitoylation+++GO:1903830///magnesium ion transmembrane transport 243996 243996 '4933405O20Rik' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004449///isocitrate dehydrogenase (NAD+) activity+++GO:0005524///ATP binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0046872///metal ion binding" GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process 244049 244049 'Mctp2' mRNA 92 95 72 0.84 0.83 0.68 2.27 2.39 2.3 0.783333333 2.32 263 276 279 86.33333333 272.6666667 5.66E-18 1.65193287 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0046928///regulation of neurotransmitter secretion 244058 244058 'Rgma' mRNA 1171 1078 380 17.89 16.22 6.12 5.76 6.04 5.95 13.41 5.916666667 431 447 434 876.3333333 437.3333333 0.046637067 -0.992232818 04350///TGF-beta signaling pathway+++04360///Axon guidance GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:1990459///transferrin receptor binding GO:0001843///neural tube closure+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010975///regulation of neuron projection development+++GO:0010976///positive regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0030509///BMP signaling pathway+++GO:0030510///regulation of BMP signaling pathway+++GO:0031175///neuron projection development+++GO:0043547///positive regulation of GTPase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048671///negative regulation of collateral sprouting+++GO:0048681///negative regulation of axon regeneration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:1900121///negative regulation of receptor binding 244059 244059 'Chd2' mRNA 1279 1459 1286 7.4 8.29 7.89 4.48 4.42 4.93 7.86 4.61 892 861 952 1341.333333 901.6666667 7.08E-11 -0.583694465 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007517///muscle organ development+++GO:0032508///DNA duplex unwinding+++GO:0060218///hematopoietic stem cell differentiation 244071 244071 'Agbl1' mRNA 48 34 32 0.73 0.51 0.53 0.01 0.01 0 0.59 0.006666667 1 1 0 38 0.666666667 8.82E-07 -5.84161647 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0035609///C-terminal protein deglutamylation+++GO:0035610///protein side chain deglutamylation 244091 244091 'Fsd2' mRNA 18 21 32 0.33 0.38 0.63 1.17 1.17 1.56 0.446666667 1.3 73 71 94 23.66666667 79.33333333 6.19E-06 1.725071865 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0008150///biological_process 244141 244141 'Nars2' mRNA 664.86 644.95 552.2 6.06 6.07 5.92 4.77 4.51 4.37 6.016666667 4.55 554.11 480.21 498.53 620.67 510.95 0.01480481 -0.289921732 00970///Aminoacyl-tRNA biosynthesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004816///asparagine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006421///asparaginyl-tRNA aminoacylation 244144 244144 'Usp35' mRNA 210 238 151 2.68 3.13 2.12 2.17 2.09 2.37 2.643333333 2.21 181 175 188 199.6666667 181.3333333 0.561534298 -0.143060544 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 244152 244152 'Tsku' mRNA 142 135 130 3.06 2.85 2.97 2.87 2.69 2.97 2.96 2.843333333 158 141 163 135.6666667 154 0.49284354 0.171121367 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0031012///extracellular matrix GO:0005515///protein binding+++GO:0050431///transforming growth factor beta binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008203///cholesterol metabolic process+++GO:0010468///regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0021540///corpus callosum morphogenesis+++GO:0021670///lateral ventricle development+++GO:0021766///hippocampus development+++GO:0021960///anterior commissure morphogenesis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032911///negative regulation of transforming growth factor beta1 production+++GO:0033344///cholesterol efflux+++GO:0042060///wound healing+++GO:0042632///cholesterol homeostasis+++GO:0042635///positive regulation of hair cycle+++GO:0043010///camera-type eye development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0061073///ciliary body morphogenesis+++GO:0097009///energy homeostasis+++GO:1904761///negative regulation of myofibroblast differentiation 244183 244183 'Trim30b' mRNA 1.88 5.18 7.05 0.04 0.1 0.15 0.29 0.28 0.19 0.096666667 0.253333333 16.46 15.73 10.54 4.703333333 14.24333333 0.089205793 1.630633711 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 244189 244189 'Gm4972' mRNA 0 1.89 0 0 0.1 0 0 0 0 0.033333333 0 0 0 0 0.63 0 0.863090843 -0.97353728 244198 244198 'Olfml1' mRNA 1077 1073 1047 31.2 30.62 32.17 25.78 26.71 24.78 31.33 25.75666667 1023 1035 952 1065.666667 1003.333333 0.345011498 -0.098785375 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 244202 244202 'Nlrp10' mRNA 7 5 19 0.08 0.06 0.24 0.06 0.03 0.08 0.126666667 0.056666667 6 3 7 10.33333333 5.333333333 0.362436134 -0.998057599 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0045087///innate immune response+++GO:0050729///positive regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050832///defense response to fungus+++GO:1900426///positive regulation of defense response to bacterium+++GO:2000318///positive regulation of T-helper 17 type immune response 244209 244209 'Cyp2r1' mRNA 6 4 5 0.23 0.14 0.19 0.66 0.75 0.55 0.186666667 0.653333333 15 22 14 5 17 0.030648614 1.755852614 00100///Steroid biosynthesis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:1902271///D3 vitamins binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0010038///response to metal ion+++GO:0010164///response to cesium ion+++GO:0010212///response to ionizing radiation+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0042359///vitamin D metabolic process+++GO:0042368///vitamin D biosynthetic process+++GO:0042738///exogenous drug catabolic process 244216 244216 'Zfp771' mRNA 483.74 548.15 473.2 21.58 23.79 21.99 22.9 22.84 21.65 22.45333333 22.46333333 592.11 569.9 536.09 501.6966667 566.0333333 0.207084092 0.163594052 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 244218 244218 'Ctf2' mRNA 14 7 4 1.07 0.51 0.31 0.13 0.11 0 0.63 0.08 2 1 0 8.333333333 1 0.037646468 -3.061676049 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005146///leukemia inhibitory factor receptor binding+++GO:0005515///protein binding GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein 244219 244219 'Zfp668' mRNA 445.3 472.67 412.82 2.97 3.09 2.92 2.5 2.31 2.61 2.993333333 2.473333333 431.16 387.6 434.04 443.5966667 417.6 0.531168032 -0.096694281 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 244233 244233 'Cd163l1' mRNA 9 1 2 0.14 0.02 0.03 0.13 0.1 0.21 0.063333333 0.146666667 10 7 15 4 10.66666667 0.213585328 1.410597033 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005044///scavenger receptor activity GO:0006897///endocytosis+++GO:0008150///biological_process 244234 244234 '5830411N06Rik' mRNA 0 0 2 0 0 0.04 0.02 0 0.02 0.013333333 0.013333333 1 0 1 0.666666667 0.666666667 0.990920981 -0.084165033 GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005044///scavenger receptor activity GO:0002365///gamma-delta T cell lineage commitment+++GO:0006897///endocytosis+++GO:0032620///interleukin-17 production 244237 244237 'Tnfrsf26' mRNA 10 15 4 0.18 0.27 0.08 2.54 2.45 2.51 0.176666667 2.5 158 151 152 9.666666667 153.6666667 2.16E-26 3.986541754 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process 244238 244238 'Mrgpre' mRNA 131 205 175 1.93 3.28 2.8 2.26 2.35 2.53 2.67 2.38 172 176 181 170.3333333 176.3333333 0.888377162 0.038269692 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 244281 244281 'Myo16' mRNA 177 169 129 1.29 1.2 0.99 0.15 0.2 0.18 1.16 0.176666667 24 31 27 158.3333333 27.33333333 5.62E-19 -2.539274545 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019903///protein phosphatase binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0008285///negative regulation of cell proliferation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0021549///cerebellum development+++GO:0048812///neuron projection morphogenesis+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 244310 244310 'Dlgap2' mRNA 38 32 34 0.25 0.22 0.17 0.02 0 0 0.213333333 0.006666667 2 0 1 34.66666667 1 5.19E-07 -5.13110708 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099572///postsynaptic specialization GO:0019904///protein domain specific binding+++GO:0060090///molecular adaptor activity GO:0007270///neuron-neuron synaptic transmission+++GO:0023052///signaling+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity 244329 244329 'Mcph1' mRNA 238 232 198 2.18 2.32 2.05 3.12 2.94 3.15 2.183333333 3.07 358.84 323 334 222.6666667 338.6133333 9.58E-05 0.593727027 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0042802///identical protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000132///establishment of mitotic spindle orientation+++GO:0000278///mitotic cell cycle+++GO:0010468///regulation of gene expression+++GO:0021987///cerebral cortex development+++GO:0043549///regulation of kinase activity+++GO:0046605///regulation of centrosome cycle+++GO:0050727///regulation of inflammatory response+++GO:0060348///bone development+++GO:0060623///regulation of chromosome condensation+++GO:0071539///protein localization to centrosome+++GO:0071850///mitotic cell cycle arrest+++GO:0097150///neuronal stem cell population maintenance 244349 244349 'Kat6a' mRNA 1921 1878 1565 11.04 10.61 9.53 8.87 7.78 8.97 10.39333333 8.54 1779 1523 1743 1788 1681.666667 0.317330662 -0.097740386 04550///Signaling pathways regulating pluripotency of stem cells GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0070776///MOZ/MORF histone acetyltransferase complex "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding+++GO:0046872///metal ion binding" "GO:0003007///heart morphogenesis+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006473///protein acetylation+++GO:0010628///positive regulation of gene expression+++GO:0016573///histone acetylation+++GO:0030099///myeloid cell differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0035162///embryonic hemopoiesis+++GO:0035909///aorta morphogenesis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043966///histone H3 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048513///animal organ development+++GO:0060325///face morphogenesis+++GO:0090398///cellular senescence" 244373 244373 'Erlin2' mRNA 3001 3112 3024 40.88 41.62 43.68 29.09 28.05 27.54 42.06 28.22666667 2451 2303 2245 3045.666667 2333 2.86E-09 -0.397366483 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0031625///ubiquitin protein ligase binding GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032933///SREBP signaling pathway+++GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0045717///negative regulation of fatty acid biosynthetic process 244416 244416 'Ppp1r3b' mRNA 585 579 581 7.42 7.15 7.75 10.36 10.79 11.74 7.44 10.96333333 944 958 1034 581.6666667 978.6666667 1.60E-13 0.738741592 04910///Insulin signaling pathway+++04931///Insulin resistance GO:0000164///protein phosphatase type 1 complex+++GO:0042587///glycogen granule+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019888///protein phosphatase regulator activity+++GO:0019899///enzyme binding+++GO:0050196///[phosphorylase] phosphatase activity+++GO:2001069///glycogen binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006470///protein dephosphorylation+++GO:0050790///regulation of catalytic activity 244418 244418 'Prag1' mRNA 196 166 174 2.19 1.83 2.07 2.79 2.5 2.09 2.03 2.46 287 251 208 178.6666667 248.6666667 0.017392555 0.463371595 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0008360///regulation of cell shape+++GO:0008593///regulation of Notch signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:0016477///cell migration+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:2000145///regulation of cell motility 244421 244421 'Lonrf1' mRNA 229 213 162 3.28 3.01 2.46 1.87 1.42 1.98 2.916666667 1.756666667 150 111 154 201.3333333 138.3333333 0.011983994 -0.549353881 GO:0046872///metal ion binding 244431 244431 'Sgcz' mRNA 1 0 1 0.04 0 0.04 0 0 0 0.026666667 0 0 0 0 0.666666667 0 0.746936975 -1.892661915 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016012///sarcoglycan complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0005515///protein binding GO:0048738///cardiac muscle tissue development+++GO:0060047///heart contraction+++GO:0061024///membrane organization 244484 244484 'Wdr17' mRNA 82 88 83 0.91 1.01 1.02 0.25 0.46 0.44 0.98 0.383333333 25 45 42 84.33333333 37.33333333 5.92E-04 -1.183296133 GO:0003674///molecular_function GO:0008150///biological_process 244548 244548 'Elmod2' mRNA 515 499 552 6.31 5.98 7.08 5.01 4.66 4.78 6.456666667 4.816666667 472 435 439 522 448.6666667 0.084769237 -0.233458036 GO:0005096///GTPase activator activity GO:0043547///positive regulation of GTPase activity+++GO:0050688///regulation of defense response to virus 244550 244550 'Podnl1' mRNA 7 8 6 0.24 0.27 0.18 0.18 0.17 0.09 0.23 0.146666667 6 6 3 7 5 0.705586133 -0.493932061 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix 244551 244551 'Nanos3' mRNA 17 7 2 1.5 0.42 0.22 0.17 0.52 0.43 0.713333333 0.373333333 3 7 6 8.666666667 5.333333333 0.594945199 -0.684506029 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0051726///regulation of cell cycle+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:2001234///negative regulation of apoptotic signaling pathway" 244556 244556 'Zfp791' mRNA 26.74 38.28 34.39 0.37 0.58 0.67 0.57 0.55 0.46 0.54 0.526666667 52.47 50.03 41.03 33.13666667 47.84333333 0.227528389 0.532089917 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 244562 244562 'Abcc12' mRNA 1 1 0 0.02 0.01 0 0.07 0.06 0.14 0.01 0.09 7 4 10 0.666666667 7 0.041748249 3.392466035 02010///ABC transporters GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0055085///transmembrane transport 244579 244579 'Tox3' mRNA 1068.74 1001.99 1028.67 5.34 4.75 5.16 1.5 1.38 1.05 5.083333333 1.31 434.77 347.74 386.37 1033.133333 389.6266667 1.67E-39 -1.422286159 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0042803///protein homodimerization activity+++GO:0051219///phosphoprotein binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0019722///calcium-mediated signaling+++GO:0042981///regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 244585 244585 'Rpgrip1l' mRNA 462 512 468 4.58 5.22 4.58 1.84 1.48 1.93 4.793333333 1.75 227 159 203 480.6666667 196.3333333 5.71E-18 -1.305374668 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005879///axonemal microtubule+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030054///cell junction+++GO:0032391///photoreceptor connecting cilium+++GO:0035253///ciliary rootlet+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0031870///thromboxane A2 receptor binding GO:0001701///in utero embryonic development+++GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0001889///liver development+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0021532///neural tube patterning+++GO:0021537///telencephalon development+++GO:0021549///cerebellum development+++GO:0021670///lateral ventricle development+++GO:0021772///olfactory bulb development+++GO:0022038///corpus callosum development+++GO:0032502///developmental process+++GO:0035108///limb morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0043010///camera-type eye development+++GO:0043584///nose development+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0046548///retinal rod cell development+++GO:0060039///pericardium development+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:0090102///cochlea development+++GO:1905515///non-motile cilium assembly 244608 244608 'Ccdc113' mRNA 61 66 41 2.95 3.21 2.15 0.46 0.51 0.39 2.77 0.453333333 10 11 9 56 10 1.84E-07 -2.488208805 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 244631 244631 'Pskh1' mRNA 810 840 781 13.63 13.91 13.95 12.43 11.98 10.89 13.83 11.76666667 850 800 721 810.3333333 790.3333333 0.727489395 -0.04786688 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0016310///phosphorylation 244646 244646 'Pkd1l3' mRNA 59.59 66.56 41.45 0.32 0.35 0.24 0.22 0.27 0.17 0.303333333 0.22 45.26 54.86 34.46 55.86666667 44.86 0.46566128 -0.32249202 04742///Taste transduction GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034703///cation channel complex+++GO:0043235///receptor complex GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008324///cation transmembrane transporter activity+++GO:0030246///carbohydrate binding+++GO:0033040///sour taste receptor activity GO:0001581///detection of chemical stimulus involved in sensory perception of sour taste+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0034220///ion transmembrane transport+++GO:0050915///sensory perception of sour taste+++GO:0050982///detection of mechanical stimulus+++GO:0070588///calcium ion transmembrane transport+++GO:0071468///cellular response to acidic pH+++GO:0098655///cation transmembrane transport 244650 244650 'Phlpp2' mRNA 230 242 238 1.95 2.09 2.08 1.26 1.75 1.51 2.04 1.506666667 203 196 187 236.6666667 195.3333333 0.117318576 -0.28960258 04151///PI3K-Akt signaling pathway GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042622///photoreceptor outer segment membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0016311///dephosphorylation+++GO:0021766///hippocampus development 244653 244653 'Hydin' mRNA 1516 1486 1204 5.03 4.86 4.25 0.46 0.3 0.37 4.713333333 0.376666667 158 103 124 1402 128.3333333 1.02E-154 -3.459271575 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:1990716///axonemal central apparatus+++GO:1990718///axonemal central pair projection GO:0003674///molecular_function GO:0002064///epithelial cell development+++GO:0003341///cilium movement+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0021591///ventricular system development+++GO:0060438///trachea development+++GO:1904158///axonemal central apparatus assembly 244654 244654 'Mtss2' mRNA 920.03 1005.33 760.8 10 11.05 8.9 5.53 5.31 5.44 9.983333333 5.426666667 580.82 533.76 544.46 895.3866667 553.0133333 4.66E-11 -0.703970705 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030864///cortical actin cytoskeleton+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005096///GTPase activator activity+++GO:0005543///phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0031267///small GTPase binding" GO:0007009///plasma membrane organization+++GO:0030031///cell projection assembly+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0061024///membrane organization+++GO:0090630///activation of GTPase activity+++GO:0097178///ruffle assembly+++GO:0097581///lamellipodium organization 244666 244666 'Sprtn' mRNA 386 363 387 4.77 4.42 5.06 5.01 4.52 5.36 4.75 4.963333333 473 416 484 378.6666667 457.6666667 0.067883951 0.259415921 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0016540///protein autoprocessing+++GO:0019985///translesion synthesis+++GO:0031398///positive regulation of protein ubiquitination 244667 244667 'Disc1' mRNA 92 103.26 99 0.72 0.74 1.22 1.18 0.99 0.72 0.893333333 0.963333333 116 118 115 98.08666667 116.3333333 0.399089235 0.235360296 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030286///dynein complex+++GO:0030424///axon+++GO:0036064///ciliary basal body+++GO:0044297///cell body+++GO:0045111///intermediate filament cytoskeleton+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0090724///central region of growth cone+++GO:0097546///ciliary base GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity "GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008104///protein localization+++GO:0010975///regulation of neuron projection development+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021846///cell proliferation in forebrain+++GO:0021852///pyramidal neuron migration+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0031929///TOR signaling+++GO:0032091///negative regulation of protein binding+++GO:0034613///cellular protein localization+++GO:0045773///positive regulation of axon extension+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051602///response to electrical stimulus+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060070///canonical Wnt signaling pathway+++GO:0060271///cilium assembly+++GO:0060998///regulation of dendritic spine development+++GO:0071539///protein localization to centrosome+++GO:0090128///regulation of synapse maturation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1905515///non-motile cilium assembly+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process" 244668 244668 'Sipa1l2' mRNA 253 268 237 2 2.08 1.98 1.55 1.52 1.6 2.02 1.556666667 226 217 226 252.6666667 223 0.30114113 -0.190614074 04015///Rap1 signaling pathway GO:0005737///cytoplasm GO:0005096///GTPase activator activity GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity 244672 244672 'Cwf19l2' mRNA 614.22 656.5 659.26 8.04 8.45 9.2 7.34 7.02 7.73 8.563333333 7.363333333 639.31 597.13 653.36 643.3266667 629.9333333 0.772485999 -0.043603634 GO:0071014///post-mRNA release spliceosomal complex GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome" 244682 244682 'Cntn5' mRNA 967.04 1037.17 1060.14 6.94 7.32 8.1 5.5 4.6 4.92 7.453333333 5.006666667 888.37 726.94 766.07 1021.45 793.7933333 3.93E-04 -0.379861057 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0098982///GABA-ergic synapse+++GO:0099026///anchored component of presynaptic membrane GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0007605///sensory perception of sound+++GO:0070593///dendrite self-avoidance+++GO:0099054///presynapse assembly 244694 244694 'Kdm4d' mRNA 33 27 28 0.69 0.54 0.57 0.09 0.2 0.11 0.6 0.133333333 5 11 6 29.33333333 7.333333333 0.001463267 -2.00737518 GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin+++GO:0035861///site of double-strand break GO:0003684///damaged DNA binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0001932///regulation of protein phosphorylation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0033169///histone H3-K9 demethylation+++GO:0035563///positive regulation of chromatin binding+++GO:0071479///cellular response to ionizing radiation+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 244698 244698 'Hephl1' mRNA 1 0 2 0.01 0 0.02 0 0.03 0 0.01 0.01 0 3 0 1 1 0.998591786 -0.025841413 00860///Porphyrin metabolism+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004322///ferroxidase activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0055072///iron ion homeostasis 244713 244713 'Zfp317' mRNA 884 934 842 10.98 11.56 11.23 7.39 7.42 7.73 11.25666667 7.513333333 683 670 689 886.6666667 680.6666667 4.52E-05 -0.392072561 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 244721 244721 'Zfp846' mRNA 366.38 361.36 349.01 3.89 3.89 4.39 3.1 2.9 2.19 4.056666667 2.73 322.34 281.58 250.67 358.9166667 284.8633333 0.025597098 -0.348014778 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 244723 244723 'Olfm2' mRNA 99 125 110 3.08 3.69 3.47 6.48 6.04 5.77 3.413333333 6.096666667 251 235 224 111.3333333 236.6666667 2.41E-08 1.07614671 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099243///extrinsic component of synaptic membrane GO:0005515///protein binding GO:0007601///visual perception+++GO:0007626///locomotory behavior+++GO:0009306///protein secretion+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:1905174///regulation of vascular smooth muscle cell dedifferentiation 244745 244745 'Dpy19l1' mRNA 253 301 269 3.43 3.89 3.82 5.45 4.51 5.72 3.713333333 5.226666667 465 394 486 274.3333333 448.3333333 1.53E-06 0.696458342 GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan 244757 244757 'Glb1l2' mRNA 173 171 197 2.54 2.47 3.07 1.26 1.52 1.07 2.693333333 1.283333333 99 116 81 180.3333333 98.66666667 1.31E-04 -0.884805389 GO:0005576///extracellular region+++GO:0005773///vacuole "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004565///beta-galactosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process 244813 244813 'Bsx' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007626///locomotory behavior+++GO:0042755///eating behavior+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060056///mammary gland involution" 244853 244853 'Nxpe4' mRNA 89 117 104.86 1.44 1.88 1.83 1.19 0.98 1.05 1.716666667 1.073333333 86 72 73.19 103.62 77.06333333 0.130264633 -0.437595784 GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 244859 244859 'Ankk1' mRNA 6 5 2 0.13 0.1 0.05 0.09 0.02 0.17 0.093333333 0.093333333 5 1 9 4.333333333 5 0.892724276 0.206131299 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0010564///regulation of cell cycle process+++GO:0016310///phosphorylation 244864 244864 'Layn' mRNA 271.55 239.17 279.37 4.09 3.55 4.46 15.93 18.3 17.38 4.033333333 17.20333333 1214.33 1362.91 1283.53 263.3633333 1286.923333 1.24E-87 2.277378635 GO:0001726///ruffle+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005540///hyaluronic acid binding+++GO:0030246///carbohydrate binding 244867 244867 'Arhgap20' mRNA 315 328 189 2.38 2.32 1.35 1.38 1.67 1.21 2.016666667 1.42 226 263 204 277.3333333 231 0.247433013 -0.263777404 GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity 244871 244871 'Zc3h12c' mRNA 658 590 537 4.03 3.56 3.48 2.73 2.55 2.67 3.69 2.65 512 470 485 595 489 0.015586367 -0.29321573 GO:0005634///nucleus+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 244879 244879 'Npat' mRNA 528 493 435 4.39 4.07 3.82 3.83 3.62 4.36 4.093333333 3.936666667 529 481 575 485.3333333 528.3333333 0.447786885 0.112859415 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0097504///Gemini of coiled bodies GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0008022///protein C-terminus binding "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0001701///in utero embryonic development+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 244882 244882 'Tnfaip8l3' mRNA 0 2 0 0 0.05 0 0.02 0.11 0.02 0.016666667 0.05 1 5 1 0.666666667 2.333333333 0.496584731 1.839067514 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0008526///phosphatidylinositol transporter activity+++GO:0035091///phosphatidylinositol binding GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0019216///regulation of lipid metabolic process+++GO:0042981///regulation of apoptotic process+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0048017///inositol lipid-mediated signaling+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0120009///intermembrane lipid transfer 244885 244885 'Sh2d7' mRNA 0 2.01 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.67 0 0.750387006 -1.824848553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 244886 244886 'Tmem266' mRNA 73 89 65 1.65 1.97 1.7 0.39 0.37 0.27 1.773333333 0.343333333 16 14 11 75.66666667 13.66666667 9.37E-10 -2.477155096 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0005216///ion channel activity+++GO:0015267///channel activity+++GO:0022832///voltage-gated channel activity+++GO:0042803///protein homodimerization activity GO:0006811///ion transport+++GO:0055085///transmembrane transport 244891 244891 'Scaper' mRNA 955 982 789 9.78 9.84 8.48 4.89 4.04 4.79 9.366666667 4.573333333 551 447 523 908.6666667 507 7.87E-15 -0.851031299 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding GO:0008150///biological_process 244895 244895 'Peak1' mRNA 1664 1706 1347 7.93 7.99 6.81 6.35 5.46 5.87 7.576666667 5.893333333 1536 1289 1374 1572.333333 1399.666667 0.067463739 -0.176667346 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction GO:0004672///protein kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0046777///protein autophosphorylation+++GO:0048041///focal adhesion assembly+++GO:0051893///regulation of focal adhesion assembly 244911 244911 'C2cd4a' mRNA 10 5 2 0.44 0.22 0.09 0.08 0.2 0.12 0.25 0.133333333 2 5 3 5.666666667 3.333333333 0.618010634 -0.753371688 GO:0005634///nucleus GO:0002528///regulation of vascular permeability involved in acute inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0030155///regulation of cell adhesion 244923 244923 'Klhl31' mRNA 26 21 40 0.22 0.17 0.36 0.25 0.36 0.36 0.25 0.323333333 34 48 48 29 43.33333333 0.265476503 0.558426742 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001933///negative regulation of protein phosphorylation+++GO:0046329///negative regulation of JNK cascade 244954 244954 'Prss35' mRNA 891.89 900.85 947.18 16.88 17.12 19.81 4.67 5.27 4.55 17.93666667 4.83 267.03 303.75 261.04 913.3066667 277.2733333 1.23E-47 -1.733301668 GO:0005576///extracellular region+++GO:0005739///mitochondrion GO:0004252///serine-type endopeptidase activity GO:0006508///proteolysis 244958 244958 'Mrap2' mRNA 346 374 230 9.5 9.99 6.66 10 7.9 7.91 8.716666667 8.603333333 435 331 332 316.6666667 366 0.315116496 0.20341032 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030545///receptor regulator activity+++GO:0031780///corticotropin hormone receptor binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0031783///type 5 melanocortin receptor binding+++GO:0042802///identical protein binding+++GO:0070996///type 1 melanocortin receptor binding GO:0006112///energy reserve metabolic process+++GO:0007631///feeding behavior+++GO:0072659///protein localization to plasma membrane+++GO:0097009///energy homeostasis+++GO:0106070///regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0106071///positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1903077///negative regulation of protein localization to plasma membrane 244962 244962 'Snx14' mRNA 1332 1392 1362 23.65 24.33 26.13 17.74 16.81 17.35 24.70333333 17.3 1138 1063 1087 1362 1096 1.13E-04 -0.326324667 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle "GO:0035091///phosphatidylinositol binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0015031///protein transport+++GO:0097352///autophagosome maturation 245000 245000 'Atr' mRNA 218 230 192 1.39 1.5 1.29 1.57 1.47 1.36 1.393333333 1.466666667 279 257 239 213.3333333 258.3333333 0.140060965 0.266218837 03460///Fanconi anemia pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++04214///Apoptosis - fly+++04218///Cellular senescence+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05170///Human immunodeficiency virus 1 infection GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0016605///PML body GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0032405///MutLalpha complex binding+++GO:0032407///MutSalpha complex binding "GO:0000077///DNA damage checkpoint+++GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007566///embryo implantation+++GO:0008156///negative regulation of DNA replication+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031297///replication fork processing+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0034644///cellular response to UV+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0046777///protein autophosphorylation+++GO:0051276///chromosome organization+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0071480///cellular response to gamma radiation+++GO:0090399///replicative senescence+++GO:0097694///establishment of RNA localization to telomere+++GO:1904884///positive regulation of telomerase catalytic core complex assembly" 245007 245007 'Zbtb38' mRNA 4353 4375 4396 28.71 28.46 31.05 22.38 20.36 21.09 29.40666667 21.27666667 3958 3561 3658 4374.666667 3725.666667 1.86E-04 -0.245422327 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0008327///methyl-CpG binding+++GO:0042803///protein homodimerization activity" "GO:0006275///regulation of DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 245020 245020 'Slc35g2' mRNA 443.31 471.29 489.74 15.13 15.83 17.92 13.73 13.71 14.07 16.29333333 13.83666667 442.77 438.59 450.97 468.1133333 444.11 0.569674205 -0.090719943 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 245026 245026 'Col6a6' mRNA 36 29 29 0.27 0.21 0.24 0.62 0.6 0.68 0.24 0.633333333 96 90.05 99.98 31.33333333 95.34333333 5.59E-07 1.5893299 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization 245038 245038 'Dclk3' mRNA 828 911 819 12.87 13.93 13.51 5.19 4.29 4.65 13.43666667 4.71 384 310 333 852.6666667 342.3333333 3.34E-32 -1.329001505 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:1900181///negative regulation of protein localization to nucleus 245049 245049 'Myrip' mRNA 74 46 67 0.87 0.49 0.8 0.32 0.23 0.31 0.72 0.286666667 34 25 33 62.33333333 30.66666667 0.008581171 -1.04139285 GO:0000145///exocyst+++GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0016324///apical plasma membrane+++GO:0030133///transport vesicle+++GO:0030667///secretory granule membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0051018///protein kinase A binding GO:0006886///intracellular protein transport+++GO:0030050///vesicle transport along actin filament+++GO:0032024///positive regulation of insulin secretion 245050 245050 'Gask1a' mRNA 641.78 694 621 10.18 10.92 10.61 3.91 3.78 3.11 10.57 3.6 272 253.03 208.99 652.26 244.6733333 6.27E-28 -1.427533635 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 245126 245126 'Tarm1' mRNA 4 5 7 0.24 0.3 0.39 1.18 1.81 0.99 0.31 1.326666667 29 45 29 5.333333333 34.33333333 3.04E-05 2.673085182 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0034987///immunoglobulin receptor binding "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:2000515///negative regulation of CD4-positive, alpha-beta T cell activation+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation" 245128 245128 'AU018091' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000064///L-ornithine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:0097638///L-arginine import across plasma membrane+++GO:1903352///L-ornithine transmembrane transport+++GO:1903401///L-lysine transmembrane transport 245174 245174 'Zfp937' mRNA 366.64 407.3 328.5 2.73 2.99 2.62 1.89 1.45 1.55 2.78 1.63 287.38 216.24 235.74 367.48 246.4533333 1.85E-04 -0.587956956 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 245195 245195 'Retnlg' mRNA 48 52 47 6 6.47 6.23 9.09 5.63 7.27 6.233333333 7.33 83 50 64 49 65.66666667 0.288910844 0.407560281 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity GO:0002408///myeloid dendritic cell chemotaxis+++GO:0007165///signal transduction 245240 245240 '9930111J21Rik2' mRNA 24.67 11.3 7.21 0.57 0.26 0.18 2 1.77 1.83 0.336666667 1.866666667 98.62 85.28 87.71 14.39333333 90.53666667 1.09E-10 2.680125936 GO:0005575///cellular_component+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0008150///biological_process+++GO:0035458///cellular response to interferon-beta 245263 245263 'Gm4981' mRNA 0 1 0 0 0.03 0 0.03 0 0 0.01 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 245269 245269 'Nim1k' mRNA 80 102 68 1.05 1.32 0.95 0.94 1.02 1 1.106666667 0.986666667 82 87 85 83.33333333 84.66666667 0.965123042 0.017524376 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation 245305 245305 'B230307C23Rik' mRNA 502.5 483.01 465.47 14.94 13.86 14.82 10.86 11.19 11.38 14.54 11.14333333 447.84 420.51 438.33 483.66 435.56 0.224723646 -0.163640387 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 245308 245308 'Zdhhc19' mRNA 0 2 2 0 0.13 0.14 0.06 0 0 0.09 0.02 1 0 0 1.333333333 0.333333333 0.599151493 -1.921064777 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097356///perinucleolar compartment "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation 245347 245347 'Gm4984' mRNA 0 4 1 0 0.54 0.14 0 0.12 0 0.226666667 0.04 0 1 0 1.666666667 0.333333333 0.511591187 -2.208930847 05415///Diabetic cardiomyopathy 245350 245350 'AA414768' mRNA 93 88 64 3.24 3.03 2.37 3.28 2.36 3.17 2.88 2.936666667 108 76 101 81.66666667 95 0.538593357 0.209962049 04120///Ubiquitin mediated proteolysis 245368 245368 'Zfp300' mRNA 143.22 179.46 175.96 1.27 1.57 1.66 1.01 0.85 1 1.5 0.953333333 130.96 106.76 122.59 166.2133333 120.1033333 0.033263214 -0.488267439 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 245381 245381 'Sowahd' mRNA 0 0 1 0 0 0.04 0 0 0.03 0.013333333 0.01 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 245386 245386 'Tmem255a' mRNA 348.88 421.15 363.69 7.06 8.34 7.34 3.47 2.55 2.92 7.58 2.98 183.52 131.91 148.09 377.9066667 154.5066667 7.80E-15 -1.30597208 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009617///response to bacterium 245403 245403 'Dcaf12l2' mRNA 0 1 0 0 0.02 0 0.03 0.03 0 0.006666667 0.02 2 2 0 0.333333333 1.333333333 0.609822222 1.881135788 GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process 245404 245404 'Dcaf12l1' mRNA 314 279 277 4.87 4.26 4.56 2.41 2.04 2.38 4.563333333 2.276666667 179 148 171 290 166 1.49E-06 -0.817370822 GO:0005575///cellular_component+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process 245446 245446 'Slitrk4' mRNA 1 4 6 0.01 0.02 0.04 0.03 0.02 0.06 0.023333333 0.036666667 5.07 3 11 3.666666667 6.356666667 0.60428608 0.76001349 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding GO:0007409///axonogenesis+++GO:0050807///regulation of synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:1905606///regulation of presynapse assembly 245450 245450 'Slitrk2' mRNA 9 14 9 0.06 0.09 0.06 0.06 0.02 0.05 0.07 0.043333333 11 3 8 10.66666667 7.333333333 0.602923333 -0.554258067 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005515///protein binding GO:0007409///axonogenesis+++GO:0050807///regulation of synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 245468 245468 'Pnma3' mRNA 13.59 7 4 0.22 0.11 0.07 0.08 0.07 0.01 0.133333333 0.053333333 6 5 1 8.196666667 4 0.429102669 -1.001668072 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 245469 245469 'Pdzd4' mRNA 65 66 46 1.01 1.05 0.76 0.39 0.52 0.48 0.94 0.463333333 29 36 33 59 32.66666667 0.026842368 -0.856555917 GO:0005737///cytoplasm+++GO:0005938///cell cortex 245474 245474 'Dkc1' mRNA 762.35 853.16 792 18.51 20.37 19.01 15.74 15.39 19.66 19.29666667 16.93 775.79 752 859.53 802.5033333 795.7733333 0.863090843 -0.024217638 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0015030///Cajal body+++GO:0031429///box H/ACA snoRNP complex+++GO:0090661///box H/ACA telomerase RNP complex GO:0003720///telomerase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:0034513///box H/ACA snoRNA binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0000495///box H/ACA snoRNA 3'-end processing+++GO:0001522///pseudouridine synthesis+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0007004///telomere maintenance via telomerase+++GO:0008284///positive regulation of cell proliferation+++GO:0009451///RNA modification+++GO:0031118///rRNA pseudouridine synthesis+++GO:0031120///snRNA pseudouridine synthesis+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0033979///box H/ACA snoRNA metabolic process+++GO:0042254///ribosome biogenesis+++GO:0051973///positive regulation of telomerase activity+++GO:0090666///scaRNA localization to Cajal body+++GO:0090669///telomerase RNA stabilization+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:1904872///regulation of telomerase RNA localization to Cajal body+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1990481///mRNA pseudouridine synthesis 245522 245522 'Zc4h2' mRNA 195 200 223 4.94 4.98 5.99 3.44 3.18 3.84 5.303333333 3.486666667 156 141 169 206 155.3333333 0.039262973 -0.422683707 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0003358///noradrenergic neuron development+++GO:0006513///protein monoubiquitination+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007528///neuromuscular junction development+++GO:0021522///spinal cord motor neuron differentiation+++GO:0030154///cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:2000677///regulation of transcription regulatory region DNA binding 245525 245525 'Hsf3' mRNA 3 1 1 0.05 0.02 0.02 0.04 0.02 0.04 0.03 0.033333333 3 1 2 1.666666667 2 0.912034314 0.251744262 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034605///cellular response to heat+++GO:0045944///positive regulation of transcription by RNA polymerase II" 245527 245527 'Eda2r' mRNA 55 50 59 0.96 0.79 1.17 4.71 4.53 4.91 0.973333333 4.716666667 320 288 301 54.66666667 303 6.16E-34 2.456335057 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0038023///signaling receptor activity GO:0007275///multicellular organism development+++GO:0012501///programmed cell death+++GO:0030154///cell differentiation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 245532 245532 'Awat2' mRNA 68 48 83 1.88 1.25 2.42 0.38 0.4 0.7 1.85 0.493333333 13 17 28 66.33333333 19.33333333 4.60E-05 -1.798446568 00830///Retinol metabolism+++04977///Vitamin digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0047196///long-chain-alcohol O-fatty-acyltransferase activity+++GO:0050252///retinol O-fatty-acyltransferase activity+++GO:0102966///arachidoyl-CoA:1-dodecanol O-acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006640///monoacylglycerol biosynthetic process+++GO:0010025///wax biosynthetic process+++GO:0042572///retinol metabolic process 245537 245537 'Nlgn3' mRNA 298 304 269 4.15 4.16 3.97 2.48 2.63 2.59 4.093333333 2.566666667 205 212 207 290.3333333 208 0.002356295 -0.490796187 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0060077///inhibitory synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0038023///signaling receptor activity+++GO:0042043///neurexin family protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0097110///scaffold protein binding "GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006898///receptor-mediated endocytosis+++GO:0007155///cell adhesion+++GO:0007158///neuron cell-cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007416///synapse assembly+++GO:0007612///learning+++GO:0008542///visual learning+++GO:0030534///adult behavior+++GO:0035176///social behavior+++GO:0042745///circadian sleep/wake cycle+++GO:0048488///synaptic vesicle endocytosis+++GO:0048675///axon extension+++GO:0048709///oligodendrocyte differentiation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060024///rhythmic synaptic transmission+++GO:0060079///excitatory postsynaptic potential+++GO:0060080///inhibitory postsynaptic potential+++GO:0060134///prepulse inhibition+++GO:0060291///long-term synaptic potentiation+++GO:0060999///positive regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0071625///vocalization behavior+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0098698///postsynaptic specialization assembly+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1902474///positive regulation of protein localization to synapse+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity+++GO:2000331///regulation of terminal button organization+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:2000969///positive regulation of AMPA receptor activity" 245545 245545 'Pabpc1l2a' mRNA 21.05 18.48 15.04 0.43 0.37 0.32 0.4 0.29 0.14 0.373333333 0.276666667 22.98 16.29 7.76 18.19 15.67666667 0.749787559 -0.275053933 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 245555 245555 'Nexmif' mRNA 10 7 0 0.05 0.04 0 0.03 0.04 0.02 0.03 0.03 8 10 4 5.666666667 7.333333333 0.797324406 0.391021723 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0072686///mitotic spindle GO:0001953///negative regulation of cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2001223///negative regulation of neuron migration 245572 245572 'Tbx22' mRNA 0 2 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 245578 245578 'Pcdh11x' mRNA 109 98 85 0.71 0.65 0.65 0.08 0.17 0.09 0.67 0.113333333 11 22 11 97.33333333 14.66666667 1.23E-12 -2.735693649 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0061827///sperm head+++GO:0097225///sperm midpiece GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0010923///negative regulation of phosphatase activity 245595 245595 'Zfp711' mRNA 37 28 52 0.48 0.37 0.69 0.29 0.47 0.29 0.513333333 0.35 26 40 24 39 30 0.468813497 -0.399374772 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 245596 245596 'Hdx' mRNA 57.67 46.48 57.33 0.72 0.57 0.76 0.5 0.58 0.55 0.683333333 0.543333333 46.44 51.83 48.66 53.82666667 48.97666667 0.740059118 -0.156151186 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 245607 245607 'Gprasp2' mRNA 2460.68 2470.76 2280.39 34.89 34.5 34.49 12.49 13.01 12.04 34.62666667 12.51333333 1010.43 1028.71 944.07 2403.943333 994.4033333 4.55E-69 -1.28437938 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001540///amyloid-beta binding+++GO:0001664///G protein-coupled receptor binding GO:0061484///hematopoietic stem cell homeostasis 245610 245610 'Nxf3' mRNA 11 14 7 0.18 0.22 0.12 0.02 0 0.02 0.173333333 0.013333333 1 0 1 10.66666667 0.666666667 0.006780475 -4.003327379 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0042272///nuclear RNA export factor complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0006406///mRNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 245622 245622 'Fam199x' mRNA 458 349 368 2.9 2.17 2.47 1.97 1.85 2.02 2.513333333 1.946666667 359 328 355 391.6666667 347.3333333 0.271246279 -0.185117804 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 245631 245631 'Pwwp3b' mRNA 96 96 112 1.14 1.14 1.42 1.03 1.02 1.09 1.233333333 1.046666667 99 96 102 101.3333333 99 0.877936448 -0.049204134 GO:0003674///molecular_function GO:0008150///biological_process 245638 245638 'Tbc1d8b' mRNA 158 199 166 1.42 1.76 1.58 2.06 1.74 2.1 1.586666667 1.966666667 263 218 261 174.3333333 247.3333333 0.008433405 0.493193259 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding GO:0003094///glomerular filtration+++GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 245643 245643 'Frmpd3' mRNA 1 5 0 0.01 0.04 0 0.01 0 0 0.016666667 0.003333333 1 0 0 2 0.333333333 0.43631411 -2.451421821 GO:0005575///cellular_component+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008150///biological_process 245650 245650 'Gucy2f' mRNA 235 266 216 1.3 1.43 1.25 0.45 0.46 0.48 1.326666667 0.463333333 99 89 97 239 95 4.26E-12 -1.340479074 00230///Purine metabolism+++04744///Phototransduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0007601///visual perception+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0019934///cGMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception 245666 245666 'Iqsec2' mRNA 166 159 95 1.51 1.48 0.93 1.59 1.59 1.45 1.306666667 1.543333333 197 185 163 140 181.6666667 0.129877759 0.372927832 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0098684///photoreceptor ribbon synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding "GO:0030036///actin cytoskeleton organization+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1900454///positive regulation of long-term synaptic depression" 245670 245670 'Rragb' mRNA 131 128 128 2.47 2.3 2.35 1.02 1.8 1.55 2.373333333 1.456666667 60 107 88 129 85 0.031610863 -0.609636927 04140///Autophagy - animal+++04150///mTOR signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0071986///Ragulator complex+++GO:1990131///Gtr1-Gtr2 GTPase complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0032561///guanyl ribonucleotide binding+++GO:0051020///GTPase binding GO:0009267///cellular response to starvation+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0034613///cellular protein localization+++GO:0071230///cellular response to amino acid stimulus+++GO:1904263///positive regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 245671 245671 'Klf8' mRNA 33 24 17 0.24 0.17 0.13 0.2 0.05 0.09 0.18 0.113333333 29 7 14 24.66666667 16.66666667 0.428100094 -0.579337138 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 245683 245683 'Klhl34' mRNA 155 149 142 3.28 3.1 3.18 0.81 0.87 0.85 3.186666667 0.843333333 44 46 45 148.6666667 45 8.77E-12 -1.73489701 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 245684 245684 'Cnksr2' mRNA 418 355 335 4.09 3.37 3.36 0.72 0.94 0.7 3.606666667 0.786666667 86 109 79 369.3333333 91.33333333 9.78E-28 -2.024241876 04013///MAPK signaling pathway - fly GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0009966///regulation of signal transduction+++GO:0016310///phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0099173///postsynapse organization+++GO:0120162///positive regulation of cold-induced thermogenesis 245688 245688 'Rbbp7' mRNA 3469.78 3654.62 3452.62 85.82 90.02 91.14 114.55 119.27 112 88.99333333 115.2733333 5261.73 5278.97 4912.94 3525.673333 5151.213333 1.53E-18 0.535369811 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016581///NuRD complex+++GO:0035098///ESC/E(Z) complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0010468///regulation of gene expression+++GO:0030308///negative regulation of cell growth+++GO:0031507///heterochromatin assembly+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048545///response to steroid hormone+++GO:0070370///cellular heat acclimation" 245695 245695 'Tceanc' mRNA 308 319 305 2.81 2.82 2.93 1.71 2.03 1.64 2.853333333 1.793333333 216 261 223 310.6666667 233.3333333 0.010965016 -0.423251613 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function "GO:0006351///transcription, DNA-templated" 245827 245827 'Fat2' mRNA 481 501 444 1.4 1.47 1.48 0.86 0.63 0.89 1.45 0.793333333 323 238 338 475.3333333 299.6666667 5.26E-06 -0.677477495 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0010631///epithelial cell migration+++GO:0031589///cell-substrate adhesion+++GO:0098609///cell-cell adhesion 245828 245828 'Trappc1' mRNA 860 946 861 80.58 87.94 85.62 105.1 107.14 101.01 84.71333333 104.4166667 1283 1273 1190 889 1248.666667 5.40E-08 0.478943297 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030008///TRAPP complex GO:0005515///protein binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport 245841 245841 'Polr2h' mRNA 460 514 488 39.17 43.86 43.98 55.23 50.36 53.76 42.33666667 53.11666667 734 652 698 487.3333333 694.6666667 9.60E-06 0.498496301 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005666///RNA polymerase III complex+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex+++GO:0032993///protein-DNA complex" GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 245847 245847 'Amdhd2' mRNA 553 628 542 22.38 25.06 23.27 60.46 62.13 59.46 23.57 60.68333333 1717 1724 1633 574.3333333 1691.333333 1.12E-71 1.548025811 00520///Amino sugar and nucleotide sugar metabolism "GO:0008448///N-acetylglucosamine-6-phosphate deacetylase activity+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0046872///metal ion binding+++GO:0047419///N-acetylgalactosamine-6-phosphate deacetylase activity" GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006046///N-acetylglucosamine catabolic process+++GO:0019262///N-acetylneuraminate catabolic process 245857 245857 'Ssh3' mRNA 1052 1164 855 20.85 22.72 17.97 23.08 20.95 22.01 20.51333333 22.01333333 1339 1187 1236 1023.666667 1254 0.004896562 0.285324838 04360///Axon guidance+++04810///Regulation of actin cytoskeleton GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030837///negative regulation of actin filament polymerization+++GO:0035335///peptidyl-tyrosine dephosphorylation 245860 245860 'Atg9a' mRNA 1473 1477 1458 20.53 20.26 21.58 17.52 16.61 16.3 20.79 16.81 1442 1336 1306 1469.333333 1361.333333 0.168336297 -0.123037506 04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal GO:0000407///phagophore assembly site+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0031667///response to nutrient levels+++GO:0032688///negative regulation of interferon-beta production+++GO:0034067///protein localization to Golgi apparatus+++GO:0034497///protein localization to phagophore assembly site+++GO:0044805///late nucleophagy+++GO:0045087///innate immune response 245865 245865 'Spag4' mRNA 33 54 60 1.3 2.09 2.5 1.64 1.58 1.8 1.963333333 1.673333333 48 45 51 49 48 0.923521518 -0.048201223 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0042995///cell projection GO:0042802///identical protein binding+++GO:0043495///protein membrane anchor GO:0006998///nuclear envelope organization+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 245866 245866 'Ift52' mRNA 1371 1341 1328 34.1 32.67 34.93 28.33 27.42 26.7 33.9 27.48333333 1312 1239 1193 1346.666667 1248 0.182739789 -0.122368604 GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0044292///dendrite terminus+++GO:0097542///ciliary tip+++GO:0097546///ciliary base+++GO:0097733///photoreceptor cell cilium GO:0005515///protein binding GO:0001841///neural tube formation+++GO:0001947///heart looping+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0009953///dorsal/ventral pattern formation+++GO:0030030///cell projection organization+++GO:0035720///intraciliary anterograde transport+++GO:0042073///intraciliary transport+++GO:0042733///embryonic digit morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060271///cilium assembly+++GO:0070613///regulation of protein processing+++GO:1905515///non-motile cilium assembly 245867 245867 'Pcmtd2' mRNA 2067 2070 2160 30.13 29.56 33.76 16.98 15.74 16.4 31.15 16.37333333 1308 1175 1226 2099 1236.333333 3.24E-22 -0.778127275 GO:0005737///cytoplasm GO:0004719///protein-L-isoaspartate (D-aspartate) O-methyltransferase activity GO:0006464///cellular protein modification process+++GO:0006479///protein methylation 245877 245877 'Map7d1' mRNA 1015 1082 390 16.89 17.92 7.12 13.49 24.21 20.57 13.97666667 19.42333333 904 1599 1340 829 1281 0.256544356 0.642845095 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0000226///microtubule cytoskeleton organization 245880 245880 'Wasf3' mRNA 677.62 672.95 457.51 6.81 6.17 4.77 3.14 2.52 3.04 5.916666667 2.9 371.56 283.14 362.34 602.6933333 339.0133333 3.91E-08 -0.835620924 04520///Adherens junction+++04666///Fc gamma R-mediated phagocytosis+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0031209///SCAR complex+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0071933///Arp2/3 complex binding GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0014003///oligodendrocyte development+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0031643///positive regulation of myelination+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 245884 245884 'Fam71f2' mRNA 12 15 18 0.63 0.57 0.73 0.66 0.34 0.4 0.643333333 0.466666667 19 7 14 15 13.33333333 0.842322248 -0.194585377 GO:0003674///molecular_function GO:0008150///biological_process 245886 245886 'Ankrd27' mRNA 528 581 583 8.37 9.4 9.62 7.57 8.26 8 9.13 7.943333333 581 596 563 564 580 0.863090843 0.027347843 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0043005///neuron projection+++GO:0097422///tubular endosome GO:0000149///SNARE binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0035544///negative regulation of SNARE complex assembly+++GO:0035646///endosome to melanosome transport+++GO:0043547///positive regulation of GTPase activity+++GO:0045022///early endosome to late endosome transport+++GO:0048812///neuron projection morphogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050790///regulation of catalytic activity 245902 245902 'Ccdc15' mRNA 387.7 335.79 376.04 1.59 1.42 1.77 0.76 0.6 0.64 1.593333333 0.666666667 207.93 170.87 178.27 366.51 185.69 5.00E-10 -0.999644772 GO:0005813///centrosome GO:0003674///molecular_function GO:0008150///biological_process 245944 245944 'Vps54' mRNA 342 330 339 4.72 4.49 4.97 4.55 4.38 4.53 4.726666667 4.486666667 388 365 370 337 374.3333333 0.385994443 0.13856603 GO:0000938///GARP complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0019905///syntaxin binding "GO:0006896///Golgi to vacuole transport+++GO:0007041///lysosomal transport+++GO:0015031///protein transport+++GO:0040008///regulation of growth+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050881///musculoskeletal movement+++GO:0060052///neurofilament cytoskeleton organization" 245945 245945 'Rbm47' mRNA 1211 1183 1207 12.68 12.18 13.44 17.41 15.93 16.41 12.76666667 16.58333333 1909 1699 1731 1200.333333 1779.666667 5.66E-12 0.554467142 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0016554///cytidine to uridine editing 246049 246049 'Slc36a2' mRNA 1460.87 1435 1476.96 33.76 32.69 36.16 19.2 20.59 20.74 34.20333333 20.17666667 955.88 1002.71 998.58 1457.61 985.7233333 3.35E-11 -0.577331915 04974///Protein digestion and absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005280///amino acid:proton symporter activity+++GO:0005302///L-tyrosine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0010155///regulation of proton transport+++GO:0015808///L-alanine transport+++GO:0015816///glycine transport+++GO:0015824///proline transport+++GO:0015828///tyrosine transport+++GO:0032973///amino acid export across plasma membrane+++GO:0035524///proline transmembrane transport+++GO:0070881///regulation of proline transport+++GO:1900925///positive regulation of glycine import across plasma membrane+++GO:1902600///proton transmembrane transport 246086 246086 'Onecut3' mRNA 0 1 1 0 0.01 0.01 0.01 0 0 0.006666667 0.003333333 1 0 0 0.666666667 0.333333333 0.861917436 -0.920429697 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 246102 246102 'Rttn' mRNA 247 229 202.19 2.08 1.85 1.75 1.68 1.36 1.54 1.893333333 1.526666667 228 203.09 217 226.0633333 216.03 0.745429612 -0.075329934 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016021///integral component of membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0007099///centriole replication+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0010457///centriole-centriole cohesion+++GO:0032053///ciliary basal body organization+++GO:0044782///cilium organization 246103 246103 'Atxn7' mRNA 536 512 450 4.14 3.89 3.72 2.47 2.52 2.74 3.916666667 2.576666667 373 362 401 499.3333333 378.6666667 0.001474482 -0.408369794 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016363///nuclear matrix GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0016578///histone deubiquitination+++GO:0042326///negative regulation of phosphorylation+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II 246104 246104 'Rhbdl3' mRNA 131 127 117 1.78 1.78 1.71 1.07 1.18 1.27 1.756666667 1.173333333 89 99 101 125 96.33333333 0.131238135 -0.385283008 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 246133 246133 'Kcne2' mRNA 73 74 84 2.5 2.5 3.06 0.19 0.15 0.39 2.686666667 0.243333333 6 5 12 77 7.666666667 1.05E-12 -3.343646162 04971///Gastric acid secretion GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007568///aging+++GO:0015705///iodide transport+++GO:0015798///myo-inositol transport+++GO:0033555///multicellular organismal response to stress+++GO:0034613///cellular protein localization+++GO:0034765///regulation of ion transmembrane transport+++GO:0035690///cellular response to drug+++GO:0043586///tongue development+++GO:0060306///regulation of membrane repolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086009///membrane repolarization+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1902159///regulation of cyclic nucleotide-gated ion channel activity+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1990573///potassium ion import across plasma membrane 246154 246154 'Vasn' mRNA 1882 1785 1849 32.28 30.13 33.64 25.13 24.36 26.6 32.01666667 25.36333333 1686 1596 1728 1838.666667 1670 0.074588944 -0.151971347 GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0070062///extracellular exosome GO:0005515///protein binding+++GO:0050431///transforming growth factor beta binding GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0071461///cellular response to redox state 246177 246177 'Myo1g' mRNA 23 22 32 0.38 0.36 0.56 7.74 8.59 7.62 0.433333333 7.983333333 539 584 514 25.66666667 545.6666667 1.96E-89 4.396963586 05130///Pathogenic Escherichia coli infection GO:0001891///phagocytic cup+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031256///leading edge membrane+++GO:0031982///vesicle+++GO:0042995///cell projection "GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0030898///actin-dependent ATPase activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0051015///actin filament binding" GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002456///T cell mediated immunity+++GO:0006887///exocytosis+++GO:0006909///phagocytosis+++GO:0007015///actin filament organization+++GO:0030050///vesicle transport along actin filament+++GO:0031589///cell-substrate adhesion+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0071976///cell gliding+++GO:0120117///T cell meandering migration 246179 246179 'Fktn' mRNA 1145 1149.76 1133.89 9.91 9.9 10.57 6.92 6.52 7.15 10.12666667 6.863333333 903.98 837.42 910.61 1142.883333 884.0033333 1.96E-05 -0.383558092 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0016740///transferase activity GO:0001764///neuron migration+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0008285///negative regulation of cell proliferation+++GO:0035269///protein O-linked mannosylation+++GO:0046329///negative regulation of JNK cascade+++GO:0060049///regulation of protein glycosylation 246190 246190 'Otoa' mRNA 16603 17570 17805 243.09 253.38 276.8 108.13 101.8 97.09 257.7566667 102.34 8506 7822 7403 17326 7910.333333 2.10E-70 -1.145784555 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane GO:0003674///molecular_function GO:0007160///cell-matrix adhesion+++GO:0007605///sensory perception of sound+++GO:0019226///transmission of nerve impulse 246196 246196 'Zfp277' mRNA 696.31 691.7 718.66 18.13 17.6 20.02 12.72 12.02 13.48 18.58333333 12.74 564.99 521.6 580.39 702.2233333 555.66 0.001944465 -0.351939602 GO:0005575///cellular_component GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding GO:0070301///cellular response to hydrogen peroxide+++GO:2000772///regulation of cellular senescence 246198 246198 'Mllt6' mRNA 1132 1273 967 8.2 9.06 7.43 4.82 4.71 4.7 8.23 4.743333333 763 730 723 1124 738.6666667 4.12E-10 -0.613227587 GO:0005634///nucleus GO:0031491///nucleosome binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0003014///renal system process+++GO:0007588///excretion+++GO:0010765///positive regulation of sodium ion transport+++GO:0035811///negative regulation of urine volume+++GO:0035812///renal sodium excretion+++GO:0036359///renal potassium excretion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001161///negative regulation of histone H3-K79 methylation 246221 246221 'Mpst' mRNA 30 31 33 1.3 1.39 1.56 1.76 1.02 1.82 1.416666667 1.533333333 46 26 44 31.33333333 38.66666667 0.597214093 0.286030669 00270///Cysteine and methionine metabolism+++00920///Sulfur metabolism+++04122///Sulfur relay system GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0004792///thiosulfate sulfurtransferase activity+++GO:0016740///transferase activity+++GO:0016783///sulfurtransferase activity+++GO:0016784///3-mercaptopyruvate sulfurtransferase activity+++GO:0042802///identical protein binding GO:0001822///kidney development+++GO:0001889///liver development+++GO:0019346///transsulfuration+++GO:0021510///spinal cord development+++GO:0070814///hydrogen sulfide biosynthetic process 246228 246228 'Vwa1' mRNA 1174 1325 1300 25.58 28.87 30.08 35.16 31.93 34.1 28.17666667 33.73 1818 1642 1732 1266.333333 1730.666667 4.24E-07 0.436832155 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0030198///extracellular matrix organization+++GO:0048266///behavioral response to pain 246229 246229 'Bivm' mRNA 281 266 227 4.56 4.25 3.84 4.15 3.96 4.22 4.216666667 4.11 295 276 287 258 286 0.44987747 0.139444304 GO:0005634///nucleus+++GO:0005737///cytoplasm 246256 246256 'Fcgr4' mRNA 66 76 87 3.22 3.66 4.5 29.13 29.13 33.47 3.793333333 30.57666667 686 669 762 76.33333333 705.6666667 5.34E-89 3.19485377 04145///Phagosome+++04380///Osteoclast differentiation+++04613///Neutrophil extracellular trap formation+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++05140///Leishmaniasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05322///Systemic lupus erythematosus GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0019767///IgE receptor activity+++GO:0019770///IgG receptor activity+++GO:0019863///IgE binding+++GO:0019864///IgG binding GO:0007166///cell surface receptor signaling pathway+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0042060///wound healing+++GO:0042119///neutrophil activation+++GO:0045780///positive regulation of bone resorption+++GO:0050776///regulation of immune response+++GO:0051930///regulation of sensory perception of pain+++GO:0071222///cellular response to lipopolysaccharide 246257 246257 'Ovca2' mRNA 493.31 649.31 558.9 10.36 13.42 12.45 9.14 9.39 9.4 12.07666667 9.31 500.89 502.38 498.66 567.1733333 500.6433333 0.178750299 -0.191581527 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0032526///response to retinoic acid 246277 246277 'Csad' mRNA 2443.28 2631.94 2127.52 54.28 56.37 48.97 40.32 46.1 46.8 53.20666667 44.40666667 2126.62 2343.56 2360.47 2400.913333 2276.883333 0.381463652 -0.083565603 00410///beta-Alanine metabolism+++00430///Taurine and hypotaurine metabolism+++00770///Pantothenate and CoA biosynthesis GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004068///aspartate 1-decarboxylase activity+++GO:0004782///sulfinoalanine decarboxylase activity+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding GO:0019449///L-cysteine catabolic process to hypotaurine+++GO:0019452///L-cysteine catabolic process to taurine+++GO:0019530///taurine metabolic process+++GO:0019752///carboxylic acid metabolic process+++GO:0042412///taurine biosynthetic process 246293 246293 'Klhl8' mRNA 595 579 353 10.12 9.75 6.4 2.88 3.61 3.73 8.756666667 3.406666667 195 238 243 509 225.3333333 5.31E-11 -1.175068848 GO:0005654///nucleoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 246313 246313 'Prokr2' mRNA 101 107 71 1.18 1.24 0.87 0.36 0.29 0.15 1.096666667 0.266666667 35 28 14 93 25.66666667 5.28E-07 -1.864176247 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007623///circadian rhythm 246316 246316 'Lgi2' mRNA 2 3 0 0.02 0.02 0 0.13 0.05 0.05 0.013333333 0.076666667 18 7 6 1.666666667 10.33333333 0.0374749 2.630876967 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005515///protein binding GO:1904862///inhibitory synapse assembly 246317 246317 'Neto1' mRNA 175.54 178.34 145.37 0.39 0.38 0.33 0.18 0.16 0.16 0.366666667 0.166666667 94.79 85.13 83.27 166.4166667 87.73 2.42E-05 -0.935611093 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0035255///ionotropic glutamate receptor binding GO:0007613///memory+++GO:0008542///visual learning+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0097120///receptor localization to synapse+++GO:2000312///regulation of kainate selective glutamate receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential 246691 246691 'Prok1' mRNA 23.27 15.11 34.85 0.32 0.2 0.51 0.16 0.16 0.08 0.343333333 0.133333333 13.54 12.93 6.13 24.41 10.86666667 0.070265087 -1.244889778 GO:0005576///extracellular region GO:0001664///G protein-coupled receptor binding+++GO:0008083///growth factor activity GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045765///regulation of angiogenesis+++GO:0051781///positive regulation of cell division 246694 246694 'Hps5' mRNA 645 662 584 7.35 7.55 7.27 7.05 6.4 7.04 7.39 6.83 707 610 679 630.3333333 665.3333333 0.623243903 0.066998732 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031084///BLOC-2 complex GO:0005515///protein binding GO:0006996///organelle organization+++GO:0007596///blood coagulation+++GO:0043473///pigmentation 246696 246696 'Slc25a28' mRNA 166 178 175 7.97 8.55 8.9 7.63 6.59 7.58 8.473333333 7.266666667 178 152 171 173 167 0.810419359 -0.064436578 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0015093///ferrous iron transmembrane transporter activity GO:0006811///ion transport+++GO:0048250///iron import into the mitochondrion+++GO:0055072///iron ion homeostasis 246703 246703 'Naxe' mRNA 2397 2312 2180 175.82 167.74 169.11 135.67 142.87 143.91 170.89 140.8166667 2122 2173 2173 2296.333333 2156 0.188840484 -0.10150066 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0044297///cell body GO:0000166///nucleotide binding+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0052856///NADHX epimerase activity+++GO:0052857///NADPHX epimerase activity GO:0002040///sprouting angiogenesis+++GO:0006869///lipid transport+++GO:0010874///regulation of cholesterol efflux+++GO:0016525///negative regulation of angiogenesis+++GO:0031580///membrane raft distribution+++GO:0046496///nicotinamide nucleotide metabolic process 246707 246707 'Emilin2' mRNA 1157 1226 937 15.79 16.45 13.56 19.99 23.42 20.57 15.26666667 21.32666667 1687 1930 1681 1106.666667 1766 4.17E-12 0.668571479 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0062023///collagen-containing extracellular matrix GO:0030023///extracellular matrix constituent conferring elasticity GO:0007155///cell adhesion 246709 246709 'Rgs13' mRNA 9 13 12 0.36 0.51 0.33 0.07 0 0.04 0.4 0.036666667 2 0 2 11.33333333 1.333333333 0.010902422 -3.106220459 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway 246710 246710 'Rhobtb2' mRNA 833 821.77 384.06 8.26 8.06 4.05 5.1 5.87 5.57 6.79 5.513333333 593 661.25 624.01 679.61 626.0866667 0.812031099 -0.112027755 04120///Ubiquitin mediated proteolysis GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043652///engulfment of apoptotic cell 246727 246727 'Oas3' mRNA 70.12 58.93 54.86 0.8 0.66 0.66 7.13 6.98 6.69 0.706666667 6.933333333 723.13 689.49 657.04 61.30333333 689.8866667 8.28E-104 3.496426898 04621///NOD-like receptor signaling pathway+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035395///negative regulation of chemokine (C-X-C motif) ligand 9 production+++GO:0039529///RIG-I signaling pathway+++GO:0039530///MDA-5 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071650///negative regulation of chemokine (C-C motif) ligand 5 production+++GO:0071659///negative regulation of IP-10 production+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 246728 246728 'Oas2' mRNA 132 116 111 2.13 1.96 1.64 14.13 13.9 13.16 1.91 13.73 1104 990 962 119.6666667 1018.666667 1.56E-127 3.078046969 04621///NOD-like receptor signaling pathway+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006401///RNA catabolic process+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042742///defense response to bacterium+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:1903487///regulation of lactation 246729 246729 'Oas1h' mRNA 1 0 0 0.05 0 0 0 0.03 0.09 0.016666667 0.04 0 1 3 0.333333333 1.333333333 0.608596619 1.894773281 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0016779///nucleotidyltransferase activity GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 246730 246730 'Oas1a' mRNA 771.7 842.71 755.33 27.05 29.27 28.62 92.06 85.17 86.82 28.31333333 88.01666667 3105.68 2772.24 2852.54 789.9133333 2910.153333 9.37E-142 1.870468814 04621///NOD-like receptor signaling pathway+++05160///Hepatitis C+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006006///glucose metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009615///response to virus+++GO:0032728///positive regulation of interferon-beta production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0035457///cellular response to interferon-alpha+++GO:0035458///cellular response to interferon-beta+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043129///surfactant homeostasis+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0048525///negative regulation of viral process+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060700///regulation of ribonuclease activity+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071659///negative regulation of IP-10 production+++GO:1901857///positive regulation of cellular respiration+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production 246735 246735 'AY074887' mRNA 3.05 1.09 0 0.31 0.11 0 0.09 0.18 0.25 0.14 0.173333333 1.09 2 2.78 1.38 1.956666667 0.894577642 0.340314837 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0097190///apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 246738 246738 'Dnajc28' mRNA 316 292 291 5.02 4.56 4.92 2.41 1.71 1.76 4.833333333 1.96 171 119 122 299.6666667 137.3333333 5.86E-10 -1.140406987 GO:0017119///Golgi transport complex GO:0003674///molecular_function "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0048213///Golgi vesicle prefusion complex stabilization" 246746 246746 'Cd300lf' mRNA 82 73 81 2.62 2.3 2.64 33.87 33.84 34.24 2.52 33.98333333 1222.36 1203 1196.67 78.66666667 1207.343333 2.97E-188 3.92767539 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0001786///phosphatidylserine binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005136///interleukin-4 receptor binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0097001///ceramide binding GO:0002376///immune system process+++GO:0030316///osteoclast differentiation+++GO:0033004///negative regulation of mast cell activation+++GO:0034125///negative regulation of MyD88-dependent toll-like receptor signaling pathway+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0035772///interleukin-13-mediated signaling pathway+++GO:0046718///viral entry into host cell+++GO:1902216///positive regulation of interleukin-4-mediated signaling pathway+++GO:2000426///negative regulation of apoptotic cell clearance+++GO:2000427///positive regulation of apoptotic cell clearance 246747 246747 'Adig' mRNA 41 33 37 4.84 3.88 4.64 1.14 1.38 0.64 4.453333333 1.053333333 11 13 6 37 10 5.68E-04 -1.900356898 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0045444///fat cell differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation 246779 246779 'Il27' mRNA 4 2 1 0.24 0.16 0.06 0.43 0.85 0.9 0.153333333 0.726666667 8 17 14 2.333333333 13 0.017898745 2.482304907 04060///Cytokine-cytokine receptor interaction+++04659///Th17 cell differentiation GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005829///cytosol GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0045523///interleukin-27 receptor binding GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0009617///response to bacterium+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042129///regulation of T cell proliferation+++GO:0045087///innate immune response+++GO:0045625///regulation of T-helper 1 cell differentiation 246782 246782 'Atpaf2' mRNA 935 931 797 30.06 28.55 28.48 22.23 25.42 26.54 29.03 24.73 780.6 833.18 892.84 887.6666667 835.54 0.426268683 -0.096410744 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0043461///proton-transporting ATP synthase complex assembly 246787 246787 'Slc5a2' mRNA 5.83 3.39 4.58 0.14 0.08 0.12 0.02 0 0 0.113333333 0.006666667 1.15 0 0 4.6 0.383333333 0.099597336 -3.494953098 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0005412///glucose:sodium symporter activity+++GO:0005515///protein binding+++GO:0015151///alpha-glucoside transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity GO:0000017///alpha-glucoside transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008643///carbohydrate transport+++GO:0035811///negative regulation of urine volume+++GO:0036359///renal potassium excretion+++GO:0055085///transmembrane transport+++GO:0098708///glucose import across plasma membrane+++GO:0098719///sodium ion import across plasma membrane+++GO:1904659///glucose transmembrane transport 246788 246788 'Trpv3' mRNA 14 21 12 0.13 0.19 0.12 0.13 0.07 0.09 0.146666667 0.096666667 16 9 11 15.66666667 12 0.646488144 -0.392863898 04750///Inflammatory mediator regulation of TRP channels GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0009266///response to temperature stimulus+++GO:0009408///response to heat+++GO:0034220///ion transmembrane transport+++GO:0042636///negative regulation of hair cycle+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0090280///positive regulation of calcium ion import+++GO:0098703///calcium ion import across plasma membrane 252830 252830 'Obox6' mRNA 2 0 2 0.09 0 0.1 0.08 0.04 0 0.063333333 0.04 2 1 0 1.333333333 1 0.878540591 -0.457512695 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 252837 252837 'Ackr4' mRNA 486 464 409 12.86 12.08 11.39 5.47 5.48 6.01 12.11 5.653333333 237 234 251 453 240.6666667 1.43E-11 -0.921754534 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005044///scavenger receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0019956///chemokine binding+++GO:0019957///C-C chemokine binding GO:0006897///endocytosis+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 252838 252838 'Tox' mRNA 2017 2050 2124 32.44 32.33 36.33 7.32 7.3 7.2 33.7 7.273333333 517 499 505 2063.666667 507 3.24E-119 -2.039025083 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding "GO:0001779///natural killer cell differentiation+++GO:0002362///CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment+++GO:0002364///NK T cell lineage commitment+++GO:0002521///leukocyte differentiation+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0010976///positive regulation of neuron projection development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030098///lymphocyte differentiation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0043373///CD4-positive, alpha-beta T cell lineage commitment+++GO:0043375///CD8-positive, alpha-beta T cell lineage commitment+++GO:0048535///lymph node development+++GO:0048541///Peyer's patch development+++GO:1901537///positive regulation of DNA demethylation+++GO:1902232///regulation of positive thymic T cell selection+++GO:2000179///positive regulation of neural precursor cell proliferation" 252864 252864 'Dusp15' mRNA 1246 1205 920 32.51 28.73 23.67 14.64 17.3 15.15 28.30333333 15.69666667 670 710 702 1123.666667 694 5.38E-11 -0.700752496 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006470///protein dephosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0046330///positive regulation of JNK cascade+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 252870 252870 'Usp7' mRNA 762 773 752 8.47 8.46 9.1 9 8.98 9.46 8.676666667 9.146666667 916 898 910 762.3333333 908 0.014321745 0.240335798 04068///FoxO signaling pathway+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0032991///protein-containing complex GO:0002039///p53 binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity "GO:0006111///regulation of gluconeogenesis+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0010216///maintenance of DNA methylation+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1901537///positive regulation of DNA demethylation+++GO:1905279///regulation of retrograde transport, endosome to Golgi" 252875 252875 'Mios' mRNA 404.77 478 438 5.28 6.08 5.98 4.97 4.78 4.63 5.78 4.793333333 444 395 386 440.2566667 408.3333333 0.448040775 -0.120557902 04150///mTOR signaling pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0061700///GATOR2 complex GO:0003674///molecular_function GO:0031503///protein-containing complex localization+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0034629///cellular protein-containing complex localization 252876 252876 'Gin1' mRNA 1127.93 1121.17 1016.62 14.47 14.15 14.12 10.55 9.94 10.63 14.24666667 10.37333333 936.84 851.33 939.02 1088.573333 909.0633333 0.00294735 -0.27066904 GO:0003676///nucleic acid binding GO:0015074///DNA integration 252903 252903 'Ap1s3' mRNA 41.53 30.1 20.13 0.8 0.57 0.41 0.64 0.76 0.67 0.593333333 0.69 38.45 44.69 38.85 30.58666667 40.66333333 0.438626142 0.397195515 04142///Lysosome+++05170///Human immunodeficiency virus 1 infection GO:0005794///Golgi apparatus+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030121///AP-1 adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function+++GO:0035615///clathrin adaptor activity GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 252906 252906 'Vmn1r189' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005550///pheromone binding+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 252966 252966 'Cables2' mRNA 151 144 134 2.87 2.69 2.7 2.11 1.96 2 2.753333333 2.023333333 128 117 118 143 121 0.301104693 -0.252179068 GO:0005575///cellular_component GO:0005515///protein binding GO:0007049///cell cycle+++GO:0008150///biological_process+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle 252967 252967 'Ropn1l' mRNA 54 51 49 3.89 3.64 3.74 4.65 3.74 4.49 3.756666667 4.293333333 74 58 69 51.33333333 67 0.30785832 0.371545305 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001932///regulation of protein phosphorylation+++GO:0003341///cilium movement+++GO:0030317///flagellated sperm motility+++GO:0048240///sperm capacitation 252972 252972 'Tpcn1' mRNA 1122 1193 809 12.92 13.5 9.88 9.35 11.71 10.95 12.1 10.67 935 1145 1061 1041.333333 1047 0.977670024 0.0057197 04020///Calcium signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0036019///endolysosome+++GO:0055038///recycling endosome membrane "GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005262///calcium channel activity+++GO:0015280///ligand-gated sodium channel activity+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0072345///NAADP-sensitive calcium-release channel activity+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0097682///intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0010508///positive regulation of autophagy+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0075509///endocytosis involved in viral entry into host cell 252973 252973 'Grhl2' mRNA 1163 1139 1148 14.75 13.7 14.51 7.17 6.93 6.65 14.32 6.916666667 681 632 600 1150 637.6666667 3.44E-20 -0.863968303 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005911///cell-cell junction+++GO:0016020///membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001161///intronic transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:0043565///sequence-specific DNA binding" "GO:0001701///in utero embryonic development+++GO:0001843///neural tube closure+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003382///epithelial cell morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007155///cell adhesion+++GO:0007420///brain development+++GO:0008283///cell proliferation+++GO:0008544///epidermis development+++GO:0010468///regulation of gene expression+++GO:0021915///neural tube development+++GO:0030323///respiratory tube development+++GO:0034329///cell junction assembly+++GO:0035264///multicellular organism growth+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0044030///regulation of DNA methylation+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0051973///positive regulation of telomerase activity+++GO:0060324///face development+++GO:0060463///lung lobe morphogenesis+++GO:0060487///lung epithelial cell differentiation+++GO:0060672///epithelial cell morphogenesis involved in placental branching+++GO:0061713///anterior neural tube closure+++GO:0070830///bicellular tight junction assembly+++GO:0090132///epithelium migration" 252974 252974 'Tspear' mRNA 5 10 6 0.12 0.24 0.16 0.05 0.21 0.34 0.173333333 0.2 2 9 15 7 8.666666667 0.815553581 0.311051973 GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0007219///Notch signaling pathway+++GO:0007605///sensory perception of sound+++GO:0008593///regulation of Notch signaling pathway+++GO:0022405///hair cycle process+++GO:0034505///tooth mineralization 257632 257632 'Nod2' mRNA 186 177 197 2.6 2.28 2.68 0.84 0.74 0.62 2.52 0.733333333 76 67 54 186.6666667 65.66666667 5.88E-11 -1.52302698 04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++05152///Tuberculosis+++05321///Inflammatory bowel disease GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0045335///phagocytic vesicle+++GO:0046658///anchored component of plasma membrane "GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0032500///muramyl dipeptide binding+++GO:0038187///pattern recognition receptor activity+++GO:0042834///peptidoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0050700///CARD domain binding+++GO:0051879///Hsp90 protein binding" GO:0002221///pattern recognition receptor signaling pathway+++GO:0002227///innate immune response in mucosa+++GO:0002253///activation of immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0002710///negative regulation of T cell mediated immunity+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002732///positive regulation of dendritic cell cytokine production+++GO:0002830///positive regulation of type 2 immune response+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006963///positive regulation of antibacterial peptide biosynthetic process+++GO:0006965///positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria+++GO:0007165///signal transduction+++GO:0007584///response to nutrient+++GO:0008284///positive regulation of cell proliferation+++GO:0009595///detection of biotic stimulus+++GO:0016045///detection of bacterium+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032494///response to peptidoglycan+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0032498///detection of muramyl dipeptide+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032701///negative regulation of interleukin-18 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0042742///defense response to bacterium+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050727///regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050766///positive regulation of phagocytosis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050871///positive regulation of B cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0060585///positive regulation of prostaglandin-endoperoxide synthase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071224///cellular response to peptidoglycan+++GO:0071225///cellular response to muramyl dipeptide+++GO:0071407///cellular response to organic cyclic compound+++GO:0071608///macrophage inflammatory protein-1 alpha production+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0090022///regulation of neutrophil chemotaxis+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902523///positive regulation of protein K63-linked ubiquitination+++GO:1904417///positive regulation of xenophagy+++GO:2000110///negative regulation of macrophage apoptotic process+++GO:2000363///positive regulation of prostaglandin-E synthase activity 257633 257633 'Acsf3' mRNA 663 634 515 16.7 15.68 13.97 8.73 9.85 9.8 15.45 9.46 393 431 426 604 416.6666667 1.54E-05 -0.542392212 "00061///Fatty acid biosynthesis+++00280///Valine, leucine and isoleucine degradation+++01212///Fatty acid metabolism" GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016405///CoA-ligase activity+++GO:0016874///ligase activity+++GO:0016878///acid-thiol ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0090409///malonyl-CoA synthetase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0090410///malonate catabolic process 257635 257635 'Sdsl' mRNA 125 110 117 5.6 4.82 5.57 3.88 3.41 3.74 5.33 3.676666667 97 84 89 117.3333333 90 0.134193493 -0.396234585 "00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++00290///Valine, leucine and isoleucine biosynthesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids" GO:0005739///mitochondrion GO:0003941///L-serine ammonia-lyase activity+++GO:0004794///L-threonine ammonia-lyase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding GO:0006567///threonine catabolic process+++GO:0009097///isoleucine biosynthetic process 257882 257882 'Olfr1344' mRNA 0 10 3 0 0.66 0.21 0 0 0 0.29 0 0 0 0 4.333333333 0 0.058181498 -4.551869682 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257890 257890 'Olfr12' mRNA 16 11 19 0.89 0.6 1.12 0.44 0.4 0.3 0.87 0.38 9 8 6 15.33333333 7.666666667 0.209586462 -1.022380303 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257917 257917 'Olfr314' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257926 257926 'Olfr544' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257931 257931 'Olfr317' mRNA 4 1 1 0.22 0.05 0.06 0 0 0 0.11 0 0 0 0 2 0 0.256867881 -3.442125442 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257938 257938 'Olfr1419' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257947 257947 'Olfr543' mRNA 2 8 4 0.11 0.43 0.23 0.1 0 0.05 0.256666667 0.05 2 0 1 4.666666667 1 0.217855452 -2.236776729 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 257961 257961 'Olfr1432' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258008 258008 'Olfr1513' mRNA 31.41 41.26 33.06 2.16 2.81 2.42 0.66 0.43 0.44 2.463333333 0.51 11 7 7.01 35.24333333 8.336666667 2.64E-04 -2.08300973 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258019 258019 'Olfr212' mRNA 1 0 4 0.02 0 0.09 0.02 0.02 0.02 0.036666667 0.02 1 1 1 1.666666667 1 0.785043935 -0.795024822 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258020 258020 'Olfr213' mRNA 0 2 0 0 0.13 0 0 0 0 0.043333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258060 258060 'Olfr1181' mRNA 0 2 0 0 0.14 0 0 0 0 0.046666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258064 258064 'Olfr316' mRNA 6 4 4 0.16 0.11 0.15 0 0 0.02 0.14 0.006666667 0 0 1 4.666666667 0.333333333 0.065287389 -3.712189512 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258117 258117 'Olfr1437' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050907///detection of chemical stimulus involved in sensory perception+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258198 258198 'Olfr224' mRNA 0 1 1 0 0.03 0.03 0 0 0 0.02 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258224 258224 'Olfr1358' mRNA 2 5 2 0.12 0.18 0.12 0.1 0.05 0.06 0.14 0.07 2 1 2 3 1.666666667 0.678843993 -0.850534362 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258259 258259 'Olfr1338' mRNA 9 18 12 0.37 0.83 0.66 0 0.04 0 0.62 0.013333333 0 1 0 13 0.333333333 8.46E-04 -5.189053406 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258268 258268 'Olfr1511' mRNA 37.53 26.13 19.38 2.54 1.75 1.39 0.09 0.16 0.21 1.893333333 0.153333333 1.48 2.67 3.4 27.68 2.516666667 1.25E-05 -3.773662334 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258278 258278 'Olfr284' mRNA 0 1 0 0 0.07 0 0 0 0.06 0.023333333 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258306 258306 'Olfr1337' mRNA 2 0 4 0.14 0 0.29 0 0 0 0.143333333 0 0 0 0 2 0 0.281002357 -3.494412377 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258334 258334 'Olfr1396' mRNA 0 1 0 0 0.06 0 0.06 0.06 0 0.02 0.04 1 1 0 0.333333333 0.666666667 0.863090843 0.881251873 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258335 258335 'Olfr374' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258352 258352 'Olfr692' mRNA 0 1 0 0 0.06 0 0 0.12 0 0.02 0.04 0 2 0 0.333333333 0.666666667 0.863090843 0.906692352 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258358 258358 'Olfr557' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258364 258364 'Olfr976' mRNA 18.31 20.89 18 0.35 0.39 0.36 0.12 0.14 0.14 0.366666667 0.133333333 7.21 8.02 8 19.06666667 7.743333333 0.073274598 -1.293793093 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258380 258380 'Olfr461' mRNA 7 11 9 0.48 0.75 0.66 0.18 0.19 0 0.63 0.123333333 3 3 0 9 2 0.080376791 -2.183139807 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258381 258381 'Olfr460' mRNA 5 4 2 0.27 0.21 0.07 0.03 0 0.06 0.183333333 0.03 1 0 1 3.666666667 0.666666667 0.233291261 -2.463583575 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258405 258405 'Olfr1420' mRNA 2 3 3 0.14 0.21 0.22 0.06 0.31 0.19 0.19 0.186666667 1 5 3 2.666666667 3 0.931060177 0.165182468 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258410 258410 'Olfr291' mRNA 0 1 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258412 258412 'Olfr877' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258423 258423 'Olfr1510' mRNA 76.47 97.87 70.62 4.66 5.9 4.57 0.45 0.56 0.31 5.043333333 0.44 8.52 10.33 5.6 81.65333333 8.15 1.03E-13 -3.407874706 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258424 258424 'Olfr1512' mRNA 121.59 118.74 129.94 8.38 8.1 9.5 1.5 0.8 0.5 8.66 0.933333333 25 13 7.99 123.4233333 15.33 4.76E-16 -3.051116005 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258436 258436 'Olfr458' mRNA 0 1 5 0 0.07 0.37 0.06 0.12 0.06 0.146666667 0.08 1 2 1 2 1.333333333 0.815602368 -0.638682078 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258448 258448 'Olfr92' mRNA 0 1 0 0 0.07 0 0 0 0.06 0.023333333 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258463 258463 'Olfr1393' mRNA 32.92 36.78 31.62 0.48 0.55 0.49 0.37 0.62 0.44 0.506666667 0.476666667 23.75 35.97 27.55 33.77333333 29.09 0.701700136 -0.226984293 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258464 258464 'Olfr1384' mRNA 1.03 0.98 1.93 0.06 0.06 0.13 0.06 0.26 0.16 0.083333333 0.16 1.21 4.82 2.96 1.313333333 2.996666667 0.474914412 1.791736651 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258482 258482 'Olfr266' mRNA 3 0 5 0.2 0 0.36 0 0 0 0.186666667 0 0 0 0 2.666666667 0 0.16897837 -3.9055387 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258502 258502 'Olfr279' mRNA 0 0 1 0 0 0.02 0.08 0.06 0.07 0.006666667 0.07 4 2 3 0.333333333 3 0.198438234 3.048520838 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258508 258508 'Olfr99' mRNA 1 1 1 0.07 0.07 0.08 0.19 0 0 0.073333333 0.063333333 3 0 0 1 1 0.998101967 -0.038412754 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258513 258513 'Olfr536' mRNA 1 0 0 0.01 0 0 0.01 0 0 0.003333333 0.003333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258522 258522 'Olfr1183' mRNA 0 2 2 0 0.14 0.15 0 0 0 0.096666667 0 0 0 0 1.333333333 0 0.47194918 -2.883616158 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258523 258523 'Olfr1186' mRNA 1 1 2 0.06 0.06 0.12 0 0 0 0.08 0 0 0 0 1.333333333 0 0.427695243 -2.887820817 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258531 258531 'Olfr315' mRNA 23 15 13 1.47 0.95 0.88 0 0.06 0.12 1.1 0.06 0 1 2 17 1 5.31E-04 -4.089661557 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258571 258571 'Olfr1033' mRNA 42 49 46 0.89 1.04 1.03 1.64 1.39 1.84 0.986666667 1.623333333 90 73 96.68 45.66666667 86.56 0.004213512 0.905682899 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258608 258608 'Olfr986' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258636 258636 'Olfr1155' mRNA 0 1 0 0 0.07 0 0 0.12 0.06 0.023333333 0.06 0 2 1 0.333333333 1 0.72821651 1.486186695 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258676 258676 'Olfr1424' mRNA 0 0 2 0 0 0.15 0 0 0 0.05 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258678 258678 'Olfr1441' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258708 258708 'Olfr1342' mRNA 0 1 0 0 0.07 0 0 0.12 0.03 0.023333333 0.05 0 2 1 0.333333333 1 0.72821651 1.486186695 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258712 258712 'Olfr433' mRNA 0 4 0 0 0.25 0 0.22 0.11 0.46 0.083333333 0.263333333 4 2 8 1.333333333 4.666666667 0.341118175 1.826533423 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258745 258745 'Olfr689' mRNA 2 1 0 0.13 0.07 0 0 0.06 0 0.066666667 0.02 0 1 0 1 0.333333333 0.734312035 -1.462250413 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258755 258755 'Olfr672' mRNA 0 1 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258756 258756 'Olfr414' mRNA 0 1 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258758 258758 'Olfr1406' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258768 258768 'Olfr1189' mRNA 1 0 0 0.07 0 0 0 0.06 0 0.023333333 0.02 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258775 258775 'Olfr196' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258778 258778 'Olfr921' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258783 258783 'Olfr920' mRNA 3 1 5 0.09 0.03 0.15 0.38 0.34 0.26 0.09 0.326666667 15 13 10 3 12.66666667 0.042500207 2.048560264 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258809 258809 'Olfr651' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258814 258814 'Olfr1156' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258817 258817 'Olfr655' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258837 258837 'Olfr545' mRNA 0 1 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258883 258883 'Olfr876' mRNA 0 0 1 0 0 0.06 0.32 0.27 0.05 0.02 0.213333333 6 5 1 0.333333333 4 0.113435575 3.46467523 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258912 258912 'Olfr1378' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258913 258913 'Olfr1377' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258920 258920 'Olfr1180' mRNA 0 0 2 0 0 0.13 0 0 0 0.043333333 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258921 258921 'Olfr1188' mRNA 2 0 0 0.13 0 0 0 0 0 0.043333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258922 258922 'Olfr267' mRNA 4 0 0 0.28 0 0 0.06 0.06 0.06 0.093333333 0.06 1 1 1 1.333333333 1 0.896242496 -0.403564375 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258989 258989 'Olfr457' mRNA 5.24 1 1 0.36 0.07 0.07 0 0 0 0.166666667 0 0 0 0 2.413333333 0 0.198124232 -3.662571932 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 258998 258998 'Olfr177' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259003 259003 'Olfr172' mRNA 1 0 0 0.06 0 0 0.05 0 0 0.02 0.016666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259042 259042 'Olfr1351' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259044 259044 'Olfr1353' mRNA 0 1 0 0 0.05 0 0.04 0 0 0.016666667 0.013333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259051 259051 'Olfr658' mRNA 2 1 2 0.04 0.02 0.04 0 0.03 0 0.033333333 0.01 0 2 0 1.666666667 0.666666667 0.667131447 -1.325796378 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259055 259055 'Olfr582' mRNA 0 0 2 0 0 0.14 0 0 0 0.046666667 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259056 259056 'Olfr584' mRNA 0 6 0 0 0.4 0 0 0 0 0.133333333 0 0 0 0 2 0 0.364889809 -3.407394727 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259063 259063 'Olfr691' mRNA 2 3 7 0.13 0.2 0.49 0 0.12 0.06 0.273333333 0.06 0 2 1 4 1 0.290490852 -2.025794747 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259066 259066 'Olfr520' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 259097 259097 'Olfr558' mRNA 3 4 2 0.06 0.07 0.04 0 0.07 0.1 0.056666667 0.056666667 0 4 6 3 3.333333333 0.933539926 0.162842682 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259104 259104 'Olfr613' mRNA 50.26 41.73 33.36 0.52 0.43 0.37 0.15 0.18 0.24 0.44 0.19 16.15 18.95 26.12 41.78333333 20.40666667 0.029279422 -1.052246349 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259122 259122 'Olfr635' mRNA 0 3 0 0 0.2 0 0 0 0.03 0.066666667 0.01 0 0 0.5 1 0.166666667 0.659075281 -2.407827175 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259144 259144 'Olfr456' mRNA 19.76 16 11 1.19 0.95 0.7 0.05 0.16 0.05 0.946666667 0.086666667 1 3 1 15.58666667 1.666666667 0.002314502 -3.201087595 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 259172 259172 'Mfrp' mRNA 7.56 8.03 2.01 0.1 0.1 0.03 0.05 0.03 0.05 0.076666667 0.043333333 4.7 2.7 4.65 5.866666667 4.016666667 0.608596619 -0.760251829 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030133///transport vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0042802///identical protein binding GO:0007601///visual perception+++GO:0009306///protein secretion+++GO:0042462///eye photoreceptor cell development+++GO:0048839///inner ear development+++GO:0060041///retina development in camera-type eye 259277 259277 'Klk8' mRNA 84 104 100 5.43 6.68 6.99 7.68 6.96 6.82 6.366666667 7.153333333 133 113 122 96 122.6666667 0.205675872 0.339495308 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0030141///secretory granule+++GO:0097180///serine protease inhibitor complex GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007613///memory+++GO:0008219///cell death+++GO:0009611///response to wounding+++GO:0031642///negative regulation of myelination+++GO:0043616///keratinocyte proliferation+++GO:0048681///negative regulation of axon regeneration+++GO:0048812///neuron projection morphogenesis+++GO:0050807///regulation of synapse organization+++GO:0050808///synapse organization 259279 259279 'Tubgcp3' mRNA 991 961 975 14.78 14.21 15.48 10.33 10.02 10.48 14.82333333 10.27666667 794 752 774 975.6666667 773.3333333 2.65E-04 -0.348156993 GO:0000922///spindle pole+++GO:0000923///equatorial microtubule organizing center+++GO:0000930///gamma-tubulin complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005827///polar microtubule+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0008275///gamma-tubulin small complex GO:0043015///gamma-tubulin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007020///microtubule nucleation+++GO:0031122///cytoplasmic microtubule organization+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle 259300 259300 'Ehd2' mRNA 547 548 473 8.74 8.32 7.91 22.73 22.1 21.89 8.323333333 22.24 1658 1572 1544 522.6666667 1591.333333 5.28E-77 1.596330213 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030139///endocytic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0016197///endosomal transport+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032456///endocytic recycling+++GO:0060271///cilium assembly+++GO:0072659///protein localization to plasma membrane+++GO:0097320///plasma membrane tubulation+++GO:1901741///positive regulation of myoblast fusion+++GO:2001137///positive regulation of endocytic recycling 259301 259301 'Leap2' mRNA 0 0 1 0 0 0.18 0.15 0 0.16 0.06 0.103333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873488313 GO:0005576///extracellular region GO:0042742///defense response to bacterium+++GO:0050832///defense response to fungus+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 259302 259302 'Srgap3' mRNA 1210 1365 1205 7.18 7.96 7.57 3.88 3.56 4.35 7.57 3.93 752 674 816 1260 747.3333333 2.78E-15 -0.764708629 04360///Axon guidance GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 260297 260297 'Prrt1' mRNA 238 160 105 8.23 5.78 4.12 3.08 3.96 3.14 6.043333333 3.393333333 103 128 96 167.6666667 109 0.03334706 -0.620234131 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0045202///synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0030545///receptor regulator activity+++GO:0042802///identical protein binding GO:0006468///protein phosphorylation+++GO:0007611///learning or memory+++GO:0008104///protein localization+++GO:0034394///protein localization to cell surface+++GO:0050808///synapse organization+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:2000311///regulation of AMPA receptor activity 260299 260299 'Cadm4' mRNA 367 343 163 9.62 8.86 4.53 4.9 5.09 4.62 7.67 4.87 215 218 196 291 209.6666667 0.057338353 -0.469528727 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031252///cell leading edge+++GO:0044291///cell-cell contact zone GO:0019903///protein phosphatase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0043183///vascular endothelial growth factor receptor 1 binding+++GO:0043184///vascular endothelial growth factor receptor 2 binding GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0035020///regulation of Rac protein signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0061041///regulation of wound healing+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:2000145///regulation of cell motility 260301 260301 'Otos' mRNA 33102 32426 36274 3691.32 3594.08 4292.95 1876.73 2298.69 2040.24 3859.45 2071.886667 19234 22908 20167 33934 20769.66667 2.85E-18 -0.722132688 GO:0005576///extracellular region GO:0007605///sensory perception of sound 260302 260302 'Gga3' mRNA 889 902 645 13.69 13.61 10.64 9.86 8.56 9.01 12.64666667 9.143333333 709 629 636 812 658 0.012265065 -0.309653244 04142///Lysosome GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0031267///small GTPase binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding GO:0006622///protein targeting to lysosome+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032456///endocytic recycling+++GO:0034394///protein localization to cell surface+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0061462///protein localization to lysosome+++GO:1902430///negative regulation of amyloid-beta formation 260305 260305 'Nphp4' mRNA 605 582 534 5.73 5.24 5.44 1.59 1.35 1.39 5.47 1.443333333 184 150 162 573.6666667 165.3333333 8.74E-40 -1.806390526 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0005929///cilium+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097470///ribbon synapse+++GO:0097546///ciliary base+++GO:0097730///non-motile cilium GO:0005515///protein binding GO:0030317///flagellated sperm motility+++GO:0035845///photoreceptor cell outer segment organization+++GO:0045494///photoreceptor cell maintenance+++GO:0060041///retina development in camera-type eye+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:1904491///protein localization to ciliary transition zone 260315 260315 'Nav3' mRNA 241.02 247.57 200.28 0.66 0.74 0.71 0.97 0.98 0.88 0.703333333 0.943333333 267.5 260.14 261.41 229.6233333 263.0166667 0.310261135 0.187313997 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0016020///membrane+++GO:1990752///microtubule end GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity GO:0007026///negative regulation of microtubule depolymerization+++GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0030336///negative regulation of cell migration+++GO:0031116///positive regulation of microtubule polymerization+++GO:0032703///negative regulation of interleukin-2 production 260408 260408 'Prss45' mRNA 3 1 3 0.15 0.05 0.16 0.09 0 0.09 0.12 0.06 2 0 2 2.333333333 1.333333333 0.735526825 -0.840248694 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity GO:0006508///proteolysis 260409 260409 'Cdc42ep3' mRNA 982 994 896 24.32 24.35 23.58 19.19 19.06 17.82 24.08333333 18.69 891 860 801 957.3333333 850.6666667 0.067034463 -0.181075303 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0005515///protein binding GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly 260423 260423 'H3c7' mRNA 6 4 5.38 0.44 0.29 0.42 0.19 0.42 0.28 0.383333333 0.296666667 3.01 6.45 4.26 5.126666667 4.573333333 0.878691203 -0.214910916 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 263406 263406 'Plekhg3' mRNA 405 489 360 4.49 5.29 4.19 4.08 4.34 4.39 4.656666667 4.27 442 442 449 418 444.3333333 0.639492603 0.080959128 GO:0005575///cellular_component GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 26356 26356 'Ing1' mRNA 926 937 870 26.43 26.78 26.76 15.91 16.52 16.64 26.65666667 16.35666667 624 639 630 911 631 1.60E-08 -0.540462474 GO:0005634///nucleus GO:0035064///methylated histone binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006606///protein import into nucleus+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010941///regulation of cell death+++GO:0045893///positive regulation of transcription, DNA-templated" 26357 26357 'Abcg2' mRNA 753 805 727 19.16 19.9 19.59 23.07 22.54 23.22 19.55 22.94333333 1064 1026 1040 761.6666667 1043.333333 8.74E-07 0.443048347 01523///Antifolate resistance+++02010///ABC transporters+++04976///Bile secretion GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0031966///mitochondrial membrane+++GO:0045121///membrane raft+++GO:0098591///external side of apical plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015143///urate transmembrane transporter activity+++GO:0015225///biotin transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0032217///riboflavin transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042887///amide transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity" "GO:0007568///aging+++GO:0010039///response to iron ion+++GO:0015711///organic anion transport+++GO:0015747///urate transport+++GO:0015878///biotin transport+++GO:0019389///glucuronoside metabolic process+++GO:0032218///riboflavin transport+++GO:0032496///response to lipopolysaccharide+++GO:0032868///response to insulin+++GO:0042886///amide transport+++GO:0042908///xenobiotic transport+++GO:0043278///response to morphine+++GO:0046415///urate metabolic process+++GO:0051593///response to folic acid+++GO:0055085///transmembrane transport+++GO:0060136///embryonic process involved in female pregnancy+++GO:0065003///protein-containing complex assembly+++GO:0070633///transepithelial transport+++GO:0071392///cellular response to estradiol stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0097744///urate salt excretion+++GO:0140115///export across plasma membrane+++GO:1904479///negative regulation of intestinal absorption+++GO:1904612///response to 2,3,7,8-tetrachlorodibenzodioxine+++GO:1990748///cellular detoxification+++GO:1990961///drug transmembrane export+++GO:1990962///drug transport across blood-brain barrier" 26358 26358 'Aldh1a7' mRNA 32 33 35 0.88 0.9 1.02 0.38 0.54 0.89 0.933333333 0.603333333 16 22 36 33.33333333 24.66666667 0.438514802 -0.445122685 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0042802///identical protein binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0006068///ethanol catabolic process+++GO:0030392///fructosamine catabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0110095///cellular detoxification of aldehyde 26360 26360 'Angptl2' mRNA 387 425 436 6.12 6.6 7.3 14.79 14.18 13.39 6.673333333 14.12 1079 1009 945 416 1011 1.32E-31 1.267000613 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding GO:0001525///angiogenesis 26362 26362 'Axl' mRNA 1540 1643 1418 19.93 20.51 19.39 53.9 60.1 54.04 19.94333333 56.01333333 4804 5176 4616 1533.666667 4865.333333 4.21E-124 1.656543912 01521///EGFR tyrosine kinase inhibitor resistance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0044228///host cell surface GO:0000166///nucleotide binding+++GO:0001618///virus receptor activity+++GO:0001786///phosphatidylserine binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0032036///myosin heavy chain binding+++GO:0043548///phosphatidylinositol 3-kinase binding GO:0001764///neuron migration+++GO:0001779///natural killer cell differentiation+++GO:0001818///negative regulation of cytokine production+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0001974///blood vessel remodeling+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021885///forebrain cell migration+++GO:0030154///cell differentiation+++GO:0030168///platelet activation+++GO:0031100///animal organ regeneration+++GO:0031668///cellular response to extracellular stimulus+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0032940///secretion by cell+++GO:0033674///positive regulation of kinase activity+++GO:0034101///erythrocyte homeostasis+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035457///cellular response to interferon-alpha+++GO:0042698///ovulation cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0043277///apoptotic cell clearance+++GO:0043491///protein kinase B signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0046718///viral entry into host cell+++GO:0048469///cell maturation+++GO:0048549///positive regulation of pinocytosis+++GO:0051250///negative regulation of lymphocyte activation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060068///vagina development+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0097028///dendritic cell differentiation+++GO:0097350///neutrophil clearance+++GO:1903902///positive regulation of viral life cycle+++GO:2000669///negative regulation of dendritic cell apoptotic process 26363 26363 'Btd' mRNA 1732 1635 1542 51.48 47.46 48.11 46.82 45.09 46.54 49.01666667 46.15 1830 1711 1761 1636.333333 1767.333333 0.230890166 0.099937239 00780///Biotin metabolism+++04977///Vitamin digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005730///nucleolus+++GO:0043204///perikaryon+++GO:0045177///apical part of cell "GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0047708///biotinidase activity" GO:0006768///biotin metabolic process+++GO:0006807///nitrogen compound metabolic process 26364 26364 'Adgre5' mRNA 370 418 371 6.65 7.34 7.03 20.02 18.94 18.46 7.006666667 19.14 1281 1182 1149 386.3333333 1204 3.51E-61 1.628458009 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031256///leading edge membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding+++GO:0035374///chondroitin sulfate binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0051965///positive regulation of synapse assembly 26365 26365 'Ceacam1' mRNA 678.67 649.59 759.94 14.26 12.97 15.2 6.23 6.82 5.75 14.14333333 6.266666667 404.83 406.84 338 696.0666667 383.2233333 3.59E-11 -0.877804228 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0031225///anchored component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0042101///T cell receptor complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0071575///integral component of external side of plasma membrane GO:0001618///virus receptor activity+++GO:0003779///actin binding+++GO:0005130///granulocyte colony-stimulating factor receptor binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015125///bile acid transmembrane transporter activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0031005///filamin binding+++GO:0034235///GPI anchor binding+++GO:0035325///Toll-like receptor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046790///virion binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990782///protein tyrosine kinase binding "GO:0001558///regulation of cell growth+++GO:0001568///blood vessel development+++GO:0001818///negative regulation of cytokine production+++GO:0001915///negative regulation of T cell mediated cytotoxicity+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002859///negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0006469///negative regulation of protein kinase activity+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0010594///regulation of endothelial cell migration+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0015721///bile acid and bile salt transport+++GO:0016032///viral process+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032703///negative regulation of interleukin-2 production+++GO:0032869///cellular response to insulin stimulus+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0038016///insulin receptor internalization+++GO:0038158///granulocyte colony-stimulating factor signaling pathway+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043116///negative regulation of vascular permeability+++GO:0043318///negative regulation of cytotoxic T cell degranulation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0044319///wound healing, spreading of cells+++GO:0044793///negative regulation by host of viral process+++GO:0044794///positive regulation by host of viral process+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045216///cell-cell junction organization+++GO:0045601///regulation of endothelial cell differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0045779///negative regulation of bone resorption+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0046718///viral entry into host cell+++GO:0048541///Peyer's patch development+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0060312///regulation of blood vessel remodeling+++GO:0070237///positive regulation of activation-induced cell death of T cells+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0090331///negative regulation of platelet aggregation+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:1901143///insulin catabolic process+++GO:1903385///regulation of homophilic cell adhesion+++GO:1903387///positive regulation of homophilic cell adhesion+++GO:1903670///regulation of sprouting angiogenesis+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:2000516///positive regulation of CD4-positive, alpha-beta T cell activation+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2001187///positive regulation of CD8-positive, alpha-beta T cell activation+++GO:2001214///positive regulation of vasculogenesis" 26366 26366 'Ceacam10' mRNA 45 38 27 3.21 2.45 1.91 9.32 7.81 8.5 2.523333333 8.543333333 166 134 140.39 36.66666667 146.7966667 8.52E-13 1.991906779 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0030317///flagellated sperm motility 26367 26367 'Ceacam2' mRNA 12.33 13.41 5.06 0.21 0.22 0.09 0.02 0.02 0.07 0.173333333 0.036666667 1.17 1.16 4.61 10.26666667 2.313333333 0.054007838 -2.314950033 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0042101///T cell receptor complex+++GO:0071575///integral component of external side of plasma membrane GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0015125///bile acid transmembrane transporter activity+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0031005///filamin binding+++GO:0034235///GPI anchor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990782///protein tyrosine kinase binding GO:0001558///regulation of cell growth+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0015721///bile acid and bile salt transport+++GO:0016032///viral process+++GO:0032869///cellular response to insulin stimulus+++GO:0038016///insulin receptor internalization+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0070348///negative regulation of brown fat cell proliferation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0097009///energy homeostasis+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:1901143///insulin catabolic process+++GO:1903385///regulation of homophilic cell adhesion+++GO:1903387///positive regulation of homophilic cell adhesion+++GO:2000252///negative regulation of feeding behavior+++GO:2000346///negative regulation of hepatocyte proliferation 26370 26370 'Cetn2' mRNA 2160 2317 2114 112.12 118.78 116.42 58.08 62.75 63.9 115.7733333 61.57666667 1284 1353 1366 2197 1334.333333 1.36E-22 -0.729814698 03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0044615///nuclear pore nuclear basket+++GO:0045177///apical part of cell+++GO:0070390///transcription export complex 2+++GO:0071942///XPC complex+++GO:0097729///9+2 motile cilium GO:0005509///calcium ion binding+++GO:0008017///microtubule binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0032795///heterotrimeric G-protein binding+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007099///centriole replication+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0032465///regulation of cytokinesis+++GO:0051028///mRNA transport+++GO:0051301///cell division 26371 26371 'Ciao1' mRNA 1129 1204 1187 20.13 21.13 22.45 18.02 18.58 18.66 21.23666667 18.42 1163 1171 1166 1173.333333 1166.666667 0.863090843 -0.020730352 GO:0005737///cytoplasm+++GO:0071817///MMXD complex+++GO:0097361///CIA complex GO:0003700///DNA-binding transcription factor activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007059///chromosome segregation+++GO:0016226///iron-sulfur cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer 26372 26372 'Clcn6' mRNA 722 606 540 7.43 6.14 5.9 4.88 4.91 4.91 6.49 4.9 546 536 532 622.6666667 538 0.094433801 -0.219469324 GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005247///voltage-gated chloride channel activity+++GO:0005524///ATP binding+++GO:0015108///chloride transmembrane transporter activity+++GO:0015297///antiporter activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0009612///response to mechanical stimulus+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport 26373 26373 'Clcn7' mRNA 1354 1362 1420 17.94 17.75 19.96 21.27 19.83 21.36 18.55 20.82 1835 1680 1795 1378.666667 1770 3.07E-05 0.346360754 GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005247///voltage-gated chloride channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015108///chloride transmembrane transporter activity+++GO:0015297///antiporter activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0009268///response to pH+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport 26374 26374 'Cop1' mRNA 407.77 374.49 313 1.71 1.55 1.42 1.51 1.52 1.49 1.56 1.506666667 415.89 406.07 391.55 365.0866667 404.5033333 0.382854388 0.139469941 04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010212///response to ionizing radiation+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 263764 263764 'Creg2' mRNA 510 541 487 4.67 4.87 4.73 1.56 1.79 1.8 4.756666667 1.716666667 196 220 219 512.6666667 211.6666667 2.58E-21 -1.285925829 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus GO:0003674///molecular_function GO:0008150///biological_process 26377 26377 'Dapp1' mRNA 64 73 54 1.14 1.28 1.02 4.53 4.19 4.2 1.146666667 4.306666667 293 265 263 63.66666667 273.6666667 2.57E-25 2.094740271 04662///B cell receptor signaling pathway GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" 26378 26378 'Decr2' mRNA 909 991.27 1002.98 25.01 26.87 29.29 25.93 25.81 25.7 27.05666667 25.81333333 1082.78 1053.97 1038.99 967.75 1058.58 0.29434355 0.115197097 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008670///2,4-dienoyl-CoA reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0019166///trans-2-enoyl-CoA reductase (NADPH) activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0009062///fatty acid catabolic process 26379 26379 'Esrra' mRNA 166 164 132 4.51 4.25 3.73 4.04 4.77 5.64 4.163333333 4.816666667 173 195 234 154 200.6666667 0.084853332 0.375473588 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030278///regulation of ossification+++GO:0030522///intracellular receptor signaling pathway+++GO:0032355///response to estradiol+++GO:0042127///regulation of cell proliferation+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045667///regulation of osteoblast differentiation+++GO:0045670///regulation of osteoclast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development+++GO:1900078///positive regulation of cellular response to insulin stimulus" 26380 26380 'Esrrb' mRNA 1889 1899 1185 26.34 26.02 17.61 17.06 15.28 15.27 23.32333333 15.87 1378 1204 1195 1657.666667 1259 0.00184651 -0.399894653 04550///Signaling pathways regulating pluripotency of stem cells GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032039///integrator complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001701///in utero embryonic development+++GO:0001831///trophectodermal cellular morphogenesis+++GO:0001834///trophectodermal cell proliferation+++GO:0001892///embryonic placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0017145///stem cell division+++GO:0019827///stem cell population maintenance+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043697///cell dedifferentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0045821///positive regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048839///inner ear development+++GO:0071931///positive regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0090282///positive regulation of transcription involved in G2/M transition of mitotic cell cycle+++GO:1902459///positive regulation of stem cell population maintenance+++GO:2000035///regulation of stem cell division+++GO:2000737///negative regulation of stem cell differentiation" 263803 263803 'Pkn3' mRNA 42 49 91 0.7 0.79 1.59 2.33 1.96 1.7 1.026666667 1.996666667 157 131 112 60.66666667 133.3333333 7.21E-04 1.10621562 04151///PI3K-Akt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0010631///epithelial cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 26381 26381 'Esrrg' mRNA 127 128 129 1.23 1.19 1.29 0.3 0.23 0.23 1.236666667 0.253333333 37 28 28 128 31 1.30E-12 -2.060327474 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis" 26382 26382 'Fgd2' mRNA 596 632 523 12.42 12.99 11.51 17.11 19.25 17.25 12.30666667 17.87 1001 1090 968 583.6666667 1019.666667 4.04E-15 0.796703547 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0007010///cytoskeleton organization+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 26383 26383 'Fto' mRNA 2593 2843 2667 40.42 43.64 43.87 25.39 24.57 24.13 42.64333333 24.69666667 1857 1782 1727 2701 1788.666667 6.39E-18 -0.606823325 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0035515///oxidative RNA demethylase activity+++GO:0035516///oxidative DNA demethylase activity+++GO:0043734///DNA-N1-methyladenine dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:1990931///RNA N6-methyladenosine dioxygenase activity+++GO:1990984///tRNA demethylase activity GO:0001659///temperature homeostasis+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0010883///regulation of lipid storage+++GO:0035552///oxidative single-stranded DNA demethylation+++GO:0035553///oxidative single-stranded RNA demethylation+++GO:0040014///regulation of multicellular organism growth+++GO:0042245///RNA repair+++GO:0044065///regulation of respiratory system process+++GO:0060612///adipose tissue development+++GO:0061157///mRNA destabilization+++GO:0070350///regulation of white fat cell proliferation+++GO:0070989///oxidative demethylation+++GO:0080111///DNA demethylation+++GO:0090335///regulation of brown fat cell differentiation 26384 26384 'Gnpda1' mRNA 694 798 684 15.87 18.33 16.98 62.66 60.71 64.55 17.06 62.64 3009 2851 3026 725.3333333 2962 8.54E-158 2.019401722 00520///Amino sugar and nucleotide sugar metabolism GO:0005737///cytoplasm GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006041///glucosamine metabolic process+++GO:0006043///glucosamine catabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006046///N-acetylglucosamine catabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0007340///acrosome reaction+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0046370///fructose biosynthetic process 26385 26385 'Grk6' mRNA 418 472 357 7.38 8.11 6.79 6.25 5.68 6.45 7.426666667 6.126666667 400 355 401 415.6666667 385.3333333 0.476379558 -0.117472336 04062///Chemokine signaling pathway+++04144///Endocytosis+++04341///Hedgehog signaling pathway - fly+++05032///Morphine addiction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0047696///beta-adrenergic receptor kinase activity GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0009966///regulation of signal transduction+++GO:0010360///negative regulation of anion channel activity+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation 26386 26386 'Hsf4' mRNA 44 49 29 1.47 1.63 1.05 1.38 1.69 1.54 1.383333333 1.536666667 47 57 49 40.66666667 51 0.468850676 0.324806241 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007601///visual perception+++GO:0008284///positive regulation of cell proliferation+++GO:0033169///histone H3-K9 demethylation+++GO:0043010///camera-type eye development+++GO:0045597///positive regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0070306///lens fiber cell differentiation" 263876 263876 'Spata2' mRNA 596 566 491 8.41 7.77 7.33 6.92 7.01 7.63 7.836666667 7.186666667 570 567 609.99 551 582.33 0.633705294 0.070129244 04217///Necroptosis GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0030159///receptor signaling complex scaffold activity+++GO:0044877///protein-containing complex binding+++GO:1990381///ubiquitin-specific protease binding GO:0007283///spermatogenesis+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0012501///programmed cell death+++GO:0050727///regulation of inflammatory response+++GO:0060544///regulation of necroptotic process+++GO:0070266///necroptotic process+++GO:0070536///protein K63-linked deubiquitination+++GO:0072520///seminiferous tubule development+++GO:1990108///protein linear deubiquitination 26388 26388 'Ifi202b' mRNA 47 56 47 1.51 1.77 1.6 17.8 17.56 15.45 1.626666667 16.93666667 637 613 535 50 595 4.09E-89 3.562069575 04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0009617///response to bacterium+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0045824///negative regulation of innate immune response 26390 26390 'Mapkbp1' mRNA 615 641 609 4.65 4.76 4.87 3.18 2.21 2.73 4.76 2.706666667 484 328 402 621.6666667 404.6666667 3.71E-06 -0.634212455 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0097431///mitotic spindle pole GO:0005515///protein binding GO:0007256///activation of JNKK activity+++GO:0032717///negative regulation of interleukin-8 production+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade+++GO:1900425///negative regulation of defense response to bacterium 26394 26394 'Lypla2' mRNA 1818 1882 1664 66.74 68.1 64.81 69.82 70.4 66.2 66.55 68.80666667 2183 2149 2004 1788 2112 0.001772757 0.230069208 00564///Glycerophospholipid metabolism GO:0005737///cytoplasm+++GO:0005795///Golgi stack GO:0004622///lysophospholipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0046464///acylglycerol catabolic process+++GO:1905344///prostaglandin catabolic process 26395 26395 'Map2k1' mRNA 4027 4131 4155 93.08 94.14 101.97 81.05 76.47 79.22 96.39666667 78.91333333 4026 3710 3811 4104.333333 3849 0.138006846 -0.106359778 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04320///Dorso-ventral axis formation+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05132///Salmonella infection+++05135///Yersinia infection+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0031267///small GTPase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0097110///scaffold protein binding "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0000278///mitotic cell cycle+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0006468///protein phosphorylation+++GO:0006979///response to oxidative stress+++GO:0007050///cell cycle arrest+++GO:0007507///heart development+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021697///cerebellar cortex formation+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030878///thyroid gland development+++GO:0032147///activation of protein kinase activity+++GO:0032402///melanosome transport+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034111///negative regulation of homotypic cell-cell adhesion+++GO:0042593///glucose homeostasis+++GO:0043410///positive regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0045597///positive regulation of cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045933///positive regulation of muscle contraction+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0048313///Golgi inheritance+++GO:0048538///thymus development+++GO:0048678///response to axon injury+++GO:0048679///regulation of axon regeneration+++GO:0048812///neuron projection morphogenesis+++GO:0048870///cell motility+++GO:0050772///positive regulation of axonogenesis+++GO:0051384///response to glucocorticoid+++GO:0051726///regulation of cell cycle+++GO:0060020///Bergmann glial cell differentiation+++GO:0060324///face development+++GO:0060425///lung morphogenesis+++GO:0060440///trachea formation+++GO:0060502///epithelial cell proliferation involved in lung morphogenesis+++GO:0060674///placenta blood vessel development+++GO:0060711///labyrinthine layer development+++GO:0070328///triglyceride homeostasis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090170///regulation of Golgi inheritance+++GO:0090398///cellular senescence+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:2000641///regulation of early endosome to late endosome transport+++GO:2001171///positive regulation of ATP biosynthetic process" 26396 26396 'Map2k2' mRNA 3549 3417 3360 83.54 79.12 83.99 77.83 75.91 78.06 82.21666667 77.26666667 3816 3637 3707 3442 3720 0.137304139 0.099885704 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04218///Cellular senescence+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05135///Yersinia infection+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030165///PDZ domain binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046872///metal ion binding+++GO:0060090///molecular adaptor activity+++GO:0097110///scaffold protein binding "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030878///thyroid gland development+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048538///thymus development+++GO:0048679///regulation of axon regeneration+++GO:0050772///positive regulation of axonogenesis+++GO:0060324///face development+++GO:0060425///lung morphogenesis+++GO:0060440///trachea formation+++GO:0060502///epithelial cell proliferation involved in lung morphogenesis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090170///regulation of Golgi inheritance+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:2000147///positive regulation of cell motility+++GO:2000641///regulation of early endosome to late endosome transport" 26397 26397 'Map2k3' mRNA 1176 1251 1122 30.48 31.94 30.85 64.72 65.11 62.79 31.09 64.20666667 2871 2820 2696 1183 2795.666667 1.30E-71 1.230057971 "04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04218///Cellular senescence+++04620///Toll-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04714///Thermogenesis+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05135///Yersinia infection+++05145///Toxoplasmosis+++05161///Hepatitis B+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001817///regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035331///negative regulation of hippo signaling+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038066///p38MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0060048///cardiac muscle contraction+++GO:0071222///cellular response to lipopolysaccharide" 26398 26398 'Map2k4' mRNA 1143 1106 698 16.5 15.74 10.69 9.31 12.41 9.98 14.31 10.56666667 744 963 772 982.3333333 826.3333333 0.129049127 -0.248861609 "04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04361///Axon regeneration+++04620///Toll-like receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04912///GnRH signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0032839///dendrite cytoplasm+++GO:0043204///perikaryon GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008545///JUN kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0009611///response to wounding+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045740///positive regulation of DNA replication+++GO:0046330///positive regulation of JNK cascade+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0071260///cellular response to mechanical stimulus+++GO:0072709///cellular response to sorbitol+++GO:2000672///negative regulation of motor neuron apoptotic process 26399 26399 'Map2k6' mRNA 3385 3481 3481 67.05 67.61 75.72 54.18 54.14 53.3 70.12666667 53.87333333 2976 2872 2853 3449 2900.333333 9.02E-05 -0.263092371 "04010///MAPK signaling pathway+++04015///Rap1 signaling pathway+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05135///Yersinia infection+++05145///Toxoplasmosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019211///phosphatase activator activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001649///osteoblast differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0022602///ovulation cycle process+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity+++GO:0051403///stress-activated MAPK cascade+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0060048///cardiac muscle contraction+++GO:0060348///bone development+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0072709///cellular response to sorbitol+++GO:0120163///negative regulation of cold-induced thermogenesis 26400 26400 'Map2k7' mRNA 2044 2138 1585 33.81 34.34 27.51 22.49 20.11 20.14 31.88666667 20.91333333 1579 1358 1344 1922.333333 1427 4.30E-06 -0.437282195 04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04141///Protein processing in endoplasmic reticulum+++04214///Apoptosis - fly+++04361///Axon regeneration+++04380///Osteoclast differentiation+++04530///Tight junction+++04620///Toll-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++04926///Relaxin signaling pathway+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05135///Yersinia infection+++05161///Hepatitis B+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008545///JUN kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0046872///metal ion binding "GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006970///response to osmotic stress+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0009408///response to heat+++GO:0009411///response to UV+++GO:0009611///response to wounding+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0034612///response to tumor necrosis factor+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade+++GO:0051403///stress-activated MAPK cascade+++GO:0051973///positive regulation of telomerase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:1904355///positive regulation of telomere capping+++GO:2000671///regulation of motor neuron apoptotic process" 26401 26401 'Map3k1' mRNA 1599 1433 1630 13.02 11.56 14.11 15.7 13.71 15.18 12.89666667 14.86333333 2233 1912 2094 1554 2079.666667 9.73E-06 0.40439273 "04010///MAPK signaling pathway+++04120///Ubiquitin mediated proteolysis+++04530///Tight junction+++04622///RIG-I-like receptor signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05161///Hepatitis B+++05166///Human T-cell leukemia virus 1 infection" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031941///filamentous actin GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0008270///zinc ion binding+++GO:0008432///JUN kinase binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0044877///protein-containing complex binding+++GO:0046625///sphingolipid binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding GO:0000165///MAPK cascade+++GO:0000209///protein polyubiquitination+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0003382///epithelial cell morphogenesis+++GO:0006468///protein phosphorylation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006970///response to osmotic stress+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0008637///apoptotic mitochondrial changes+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030334///regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0042060///wound healing+++GO:0043010///camera-type eye development+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0050434///positive regulation of viral transcription+++GO:0061029///eyelid development in camera-type eye+++GO:0071260///cellular response to mechanical stimulus 26403 26403 'Map3k11' mRNA 1351.52 1316.49 1243.08 21.07 20.66 21.14 22.72 21.69 21.22 20.95666667 21.87666667 1616.53 1489.04 1452.64 1303.696667 1519.403333 0.010950066 0.209198666 04010///MAPK signaling pathway+++04932///Non-alcoholic fatty liver disease GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0007017///microtubule-based process+++GO:0007254///JNK cascade+++GO:0007256///activation of JNKK activity+++GO:0007257///activation of JUN kinase activity+++GO:0008219///cell death+++GO:0016310///phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0044843///cell cycle G1/S phase transition+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation 26404 26404 'Map3k12' mRNA 1109.18 1130.17 1177.67 13.83 13.42 15.49 7.17 7.2 6.59 14.24666667 6.986666667 727.24 690.55 642.59 1139.006667 686.7933333 2.95E-14 -0.74457144 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030426///growth cone GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity "GO:0006468///protein phosphorylation+++GO:0007254///JNK cascade+++GO:0007256///activation of JNKK activity+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000672///negative regulation of motor neuron apoptotic process" 26405 26405 'Map3k2' mRNA 731 729 521 3.54 3.47 2.68 2.76 2.6 2.78 3.23 2.713333333 657 603 641 660.3333333 633.6666667 0.689376793 -0.065271984 04010///MAPK signaling pathway+++04540///Gap junction+++04912///GnRH signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding "GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0071260///cellular response to mechanical stimulus" 26406 26406 'Map3k3' mRNA 423.6 403.93 349.82 3.85 3.6 3.31 5.84 5.38 5.35 3.586666667 5.523333333 712.45 635.52 646.92 392.45 664.9633333 5.69E-11 0.752195865 04010///MAPK signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++05166///Human T-cell leukemia virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0001568///blood vessel development+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046777///protein autophosphorylation+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1900745///positive regulation of p38MAPK cascade+++GO:2000773///negative regulation of cellular senescence 264064 264064 'Cdk8' mRNA 398 403 406 7.86 7.87 8.77 6.84 6.71 7.18 8.166666667 6.91 383 363 402 402.3333333 382.6666667 0.613085499 -0.085086974 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016592///mediator complex+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0051726///regulation of cell cycle+++GO:0090209///negative regulation of triglyceride metabolic process 26407 26407 'Map3k4' mRNA 1286 1247 1285 12.96 12.35 13.74 10.82 10.45 9.78 13.01666667 10.35 1235 1165 1083 1272.666667 1161 0.136705667 -0.146046 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04624///Toll and Imd signaling pathway+++04912///GnRH signaling pathway GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0001890///placenta development+++GO:0006468///protein phosphorylation+++GO:0010225///response to UV-C+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0019100///male germ-line sex determination+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035556///intracellular signal transduction+++GO:0043507///positive regulation of JUN kinase activity+++GO:0048263///determination of dorsal identity+++GO:0051973///positive regulation of telomerase activity+++GO:0060718///chorionic trophoblast cell differentiation+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1904355///positive regulation of telomere capping 26408 26408 'Map3k5' mRNA 285 280 253 2.82 2.72 2.65 1.62 1.27 1.53 2.73 1.473333333 188 145 172 272.6666667 168.3333333 4.75E-05 -0.707662885 01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04071///Sphingolipid signaling pathway+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04214///Apoptosis - fly+++04530///Tight junction+++04668///TNF signaling pathway+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0009897///external side of plasma membrane+++GO:0032991///protein-containing complex+++GO:1902911///protein kinase complex+++GO:1990604///IRE1-TRAF2-ASK1 complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0000187///activation of MAPK activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007254///JNK cascade+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010941///regulation of cell death+++GO:0016310///phosphorylation+++GO:0033554///cellular response to stress+++GO:0034198///cellular response to amino acid starvation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0038066///p38MAPK cascade+++GO:0042060///wound healing+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade+++GO:0051403///stress-activated MAPK cascade+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072577///endothelial cell apoptotic process+++GO:0097300///programmed necrotic cell death+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901216///positive regulation of neuron death+++GO:1902170///cellular response to reactive nitrogen species+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation" 26409 26409 'Map3k7' mRNA 262 304 291 2.58 2.97 3.01 3.78 2.77 2.99 2.853333333 3.18 440 318 339 285.6666667 365.6666667 0.046345581 0.340652965 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04064///NF-kappa B signaling pathway+++04140///Autophagy - animal+++04152///AMPK signaling pathway+++04214///Apoptosis - fly+++04310///Wnt signaling pathway+++04380///Osteoclast differentiation+++04520///Adherens junction+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04657///IL-17 signaling pathway+++04660///T cell receptor signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008385///IkappaB kinase complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019211///phosphatase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001649///osteoblast differentiation+++GO:0001841///neural tube formation+++GO:0002726///positive regulation of T cell cytokine production+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007252///I-kappaB phosphorylation+++GO:0007254///JNK cascade+++GO:0016239///positive regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032743///positive regulation of interleukin-2 production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043276///anoikis+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043966///histone H3 acetylation+++GO:0046330///positive regulation of JNK cascade+++GO:0051403///stress-activated MAPK cascade+++GO:0060348///bone development+++GO:0060546///negative regulation of necroptotic process+++GO:1902443///negative regulation of ripoptosome assembly involved in necroptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2001234///negative regulation of apoptotic signaling pathway 26410 26410 'Map3k8' mRNA 105 93 94 2.35 2.05 2.21 4.16 5.27 3.6 2.203333333 4.343333333 214 266 182 97.33333333 220.6666667 9.38E-08 1.170942884 04010///MAPK signaling pathway+++04620///Toll-like receptor signaling pathway+++04660///T cell receptor signaling pathway+++04668///TNF signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0016310///phosphorylation 26411 26411 'Map4k1' mRNA 29 10 19 0.47 0.16 0.36 4.05 4.3 3.86 0.33 4.07 232 242 216 19.33333333 230 2.46E-33 3.560203457 04010///MAPK signaling pathway GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0008283///cell proliferation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate 26412 26412 'Map4k2' mRNA 953 860 779 11.05 9.83 9.63 5.7 5.52 6.46 10.17 5.893333333 563 537 624 864 574.6666667 3.96E-08 -0.597756543 04010///MAPK signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding GO:0000165///MAPK cascade+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0006903///vesicle targeting+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade 26413 26413 'Mapk1' mRNA 4126 4239 1843 74.52 74.87 23.6 26.52 53.38 48.01 57.66333333 42.63666667 2486 3758 3237 3402.666667 3160.333333 0.863090843 -0.096091292 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04320///Dorso-ventral axis formation+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04520///Adherens junction+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031143///pseudopodium+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0043204///perikaryon+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0003690///double-stranded DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0042802///identical protein binding "GO:0000165///MAPK cascade+++GO:0006351///transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007507///heart development+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0009636///response to toxic substance+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0014032///neural crest cell development+++GO:0015966///diadenosine tetraphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019233///sensory perception of pain+++GO:0019858///cytosine metabolic process+++GO:0030278///regulation of ossification+++GO:0030335///positive regulation of cell migration+++GO:0030641///regulation of cellular pH+++GO:0030878///thyroid gland development+++GO:0031647///regulation of protein stability+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032496///response to lipopolysaccharide+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0034198///cellular response to amino acid starvation+++GO:0034614///cellular response to reactive oxygen species+++GO:0035094///response to nicotine+++GO:0035556///intracellular signal transduction+++GO:0038127///ERBB signaling pathway+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042473///outer ear morphogenesis+++GO:0043330///response to exogenous dsRNA+++GO:0043627///response to estrogen+++GO:0045596///negative regulation of cell differentiation+++GO:0045727///positive regulation of translation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046697///decidualization+++GO:0048538///thymus development+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051403///stress-activated MAPK cascade+++GO:0051493///regulation of cytoskeleton organization+++GO:0051973///positive regulation of telomerase activity+++GO:0060020///Bergmann glial cell differentiation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060291///long-term synaptic potentiation+++GO:0060324///face development+++GO:0060425///lung morphogenesis+++GO:0060440///trachea formation+++GO:0060716///labyrinthine layer blood vessel development+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070849///response to epidermal growth factor+++GO:0071276///cellular response to cadmium ion+++GO:0071310///cellular response to organic substance+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072584///caveolin-mediated endocytosis+++GO:0090170///regulation of Golgi inheritance+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0120041///positive regulation of macrophage proliferation+++GO:1903351///cellular response to dopamine+++GO:1904355///positive regulation of telomere capping+++GO:2000641///regulation of early endosome to late endosome transport" 264134 264134 'Ttc26' mRNA 457.39 536.64 586 5.93 6.83 8.07 2.82 2.9 3.03 6.943333333 2.916666667 251.98 250.69 260 526.6766667 254.2233333 5.85E-13 -1.069016064 GO:0005813///centrosome+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0005515///protein binding+++GO:0120170///intraciliary transport particle B binding GO:0007224///smoothened signaling pathway+++GO:0007286///spermatid development+++GO:0008594///photoreceptor cell morphogenesis+++GO:0015031///protein transport+++GO:0035082///axoneme assembly+++GO:0035720///intraciliary anterograde transport+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0046530///photoreceptor cell differentiation+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1905198///manchette assembly 26414 26414 'Mapk10' mRNA 798 867 849 6.4 6.84 7.23 0.84 0.69 0.81 6.823333333 0.78 122 99 113 838 111.3333333 1.11E-100 -2.925893336 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04212///Longevity regulating pathway - worm+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04380///Osteoclast differentiation+++04391///Hippo signaling pathway - fly+++04510///Focal adhesion+++04530///Tight junction+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004705///JUN kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007254///JNK cascade+++GO:0007258///JUN phosphorylation+++GO:0009414///response to water deprivation+++GO:0009416///response to light stimulus+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0042752///regulation of circadian rhythm+++GO:0045475///locomotor rhythm+++GO:0048511///rhythmic process+++GO:0071474///cellular hyperosmotic response+++GO:0098969///neurotransmitter receptor transport to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse 26415 26415 'Mapk13' mRNA 756 763 716 32.3 32.21 32.47 31.88 35.39 32.92 32.32666667 33.39666667 852 926 851 745 876.3333333 0.032196013 0.223862054 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0006970///response to osmotic stress+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034644///cellular response to UV+++GO:0035556///intracellular signal transduction+++GO:0051403///stress-activated MAPK cascade+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071347///cellular response to interleukin-1+++GO:0072709///cellular response to sorbitol+++GO:0072740///cellular response to anisomycin+++GO:1903936///cellular response to sodium arsenite 26416 26416 'Mapk14' mRNA 687 742 438 11.66 12.47 8.08 10.74 10.12 11.52 10.73666667 10.79333333 719 654 742 622.3333333 705 0.288582685 0.177836263 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0051525///NFAT protein binding "GO:0000077///DNA damage checkpoint+++GO:0000165///MAPK cascade+++GO:0000902///cell morphogenesis+++GO:0001502///cartilage condensation+++GO:0001525///angiogenesis+++GO:0001649///osteoblast differentiation+++GO:0001890///placenta development+++GO:0002021///response to dietary excess+++GO:0002062///chondrocyte differentiation+++GO:0006006///glucose metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007519///skeletal muscle tissue development+++GO:0010628///positive regulation of gene expression+++GO:0010831///positive regulation of myotube differentiation+++GO:0014835///myoblast differentiation involved in skeletal muscle regeneration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019395///fatty acid oxidation+++GO:0030278///regulation of ossification+++GO:0030316///osteoclast differentiation+++GO:0031281///positive regulation of cyclase activity+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0032640///tumor necrosis factor production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032868///response to insulin+++GO:0035331///negative regulation of hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0035994///response to muscle stretch+++GO:0038066///p38MAPK cascade+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042770///signal transduction in response to DNA damage+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0046777///protein autophosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0051146///striated muscle cell differentiation+++GO:0051403///stress-activated MAPK cascade+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060348///bone development+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071479///cellular response to ionizing radiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0090400///stress-induced premature senescence+++GO:0098586///cellular response to virus+++GO:0099179///regulation of synaptic membrane adhesion+++GO:1900015///regulation of cytokine production involved in inflammatory response+++GO:1901741///positive regulation of myoblast fusion+++GO:2000379///positive regulation of reactive oxygen species metabolic process" 26417 26417 'Mapk3' mRNA 1189 1120 989 38.75 35.97 34.19 45.96 50.2 49.49 36.30333333 48.55 1621 1728 1689 1099.333333 1679.333333 5.21E-13 0.602692727 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04210///Apoptosis+++04214///Apoptosis - fly+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04320///Dorso-ventral axis formation+++04350///TGF-beta signaling pathway+++04360///Axon guidance+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04520///Adherens junction+++04540///Gap junction+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05034///Alcoholism+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05160///Hepatitis C+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05216///Thyroid cancer+++05218///Melanoma+++05219///Bladder cancer+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031143///pseudopodium+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0001784///phosphotyrosine residue binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019902///phosphatase binding+++GO:0042802///identical protein binding+++GO:0097110///scaffold protein binding "GO:0000165///MAPK cascade+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006351///transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007568///aging+++GO:0009636///response to toxic substance+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0014032///neural crest cell development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0019233///sensory perception of pain+++GO:0019369///arachidonic acid metabolic process+++GO:0030278///regulation of ossification+++GO:0030509///BMP signaling pathway+++GO:0030641///regulation of cellular pH+++GO:0030878///thyroid gland development+++GO:0031281///positive regulation of cyclase activity+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032496///response to lipopolysaccharide+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033129///positive regulation of histone phosphorylation+++GO:0034198///cellular response to amino acid starvation+++GO:0034614///cellular response to reactive oxygen species+++GO:0035066///positive regulation of histone acetylation+++GO:0035556///intracellular signal transduction+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0042473///outer ear morphogenesis+++GO:0043330///response to exogenous dsRNA+++GO:0045727///positive regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046697///decidualization+++GO:0048538///thymus development+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051216///cartilage development+++GO:0051403///stress-activated MAPK cascade+++GO:0051493///regulation of cytoskeleton organization+++GO:0051973///positive regulation of telomerase activity+++GO:0060020///Bergmann glial cell differentiation+++GO:0060324///face development+++GO:0060425///lung morphogenesis+++GO:0060440///trachea formation+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0065003///protein-containing complex assembly+++GO:0070371///ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070849///response to epidermal growth factor+++GO:0071260///cellular response to mechanical stimulus+++GO:0071276///cellular response to cadmium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072584///caveolin-mediated endocytosis+++GO:0090170///regulation of Golgi inheritance+++GO:0120041///positive regulation of macrophage proliferation+++GO:1903351///cellular response to dopamine+++GO:1904355///positive regulation of telomere capping+++GO:1904417///positive regulation of xenophagy+++GO:2000641///regulation of early endosome to late endosome transport+++GO:2000657///negative regulation of apolipoprotein binding" 26419 26419 'Mapk8' mRNA 184 167 175 1.76 1.57 1.78 1.54 1.65 1.58 1.703333333 1.59 189 192 184 175.3333333 188.3333333 0.716186228 0.090849441 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04212///Longevity regulating pathway - worm+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04380///Osteoclast differentiation+++04391///Hippo signaling pathway - fly+++04510///Focal adhesion+++04530///Tight junction+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031982///vesicle+++GO:0032839///dendrite cytoplasm+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0097441///basal dendrite GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004705///JUN kinase activity+++GO:0004707///MAP kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019894///kinesin binding+++GO:0019899///enzyme binding+++GO:0035033///histone deacetylase regulator activity+++GO:0042826///histone deacetylase binding "GO:0000165///MAPK cascade+++GO:0001503///ossification+++GO:0001764///neuron migration+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0006970///response to osmotic stress+++GO:0006979///response to oxidative stress+++GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0007258///JUN phosphorylation+++GO:0009408///response to heat+++GO:0009411///response to UV+++GO:0009612///response to mechanical stimulus+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0031063///regulation of histone deacetylation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031175///neuron projection development+++GO:0031281///positive regulation of cyclase activity+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0032880///regulation of protein localization+++GO:0034198///cellular response to amino acid starvation+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0034614///cellular response to reactive oxygen species+++GO:0035556///intracellular signal transduction+++GO:0042542///response to hydrogen peroxide+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0045740///positive regulation of DNA replication+++GO:0046605///regulation of centrosome cycle+++GO:0046686///response to cadmium ion+++GO:0048263///determination of dorsal identity+++GO:0048511///rhythmic process+++GO:0048813///dendrite morphogenesis+++GO:0051247///positive regulation of protein metabolic process+++GO:0051403///stress-activated MAPK cascade+++GO:0061833///protein localization to tricellular tight junction+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071216///cellular response to biotic stimulus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071260///cellular response to mechanical stimulus+++GO:0071276///cellular response to cadmium ion+++GO:0071732///cellular response to nitric oxide+++GO:0071803///positive regulation of podosome assembly+++GO:0090045///positive regulation of deacetylase activity+++GO:0097050///type B pancreatic cell apoptotic process+++GO:0097150///neuronal stem cell population maintenance+++GO:0097300///programmed necrotic cell death+++GO:1901485///positive regulation of transcription factor catabolic process+++GO:1902595///regulation of DNA replication origin binding+++GO:1904809///regulation of dense core granule transport+++GO:2000017///positive regulation of determination of dorsal identity+++GO:2001224///positive regulation of neuron migration+++GO:2001235///positive regulation of apoptotic signaling pathway" 26420 26420 'Mapk9' mRNA 754 900 462 8.59 10.07 5.57 6.82 8.3 7.8 8.076666667 7.64 691 822 766 705.3333333 759.6666667 0.601764247 0.109921654 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04212///Longevity regulating pathway - worm+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++04217///Necroptosis+++04310///Wnt signaling pathway+++04361///Axon regeneration+++04380///Osteoclast differentiation+++04391///Hippo signaling pathway - fly+++04510///Focal adhesion+++04530///Tight junction+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04920///Adipocytokine signaling pathway+++04926///Relaxin signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05231///Choline metabolism in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043204///perikaryon GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004705///JUN kinase activity+++GO:0004707///MAP kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031435///mitogen-activated protein kinase kinase kinase binding "GO:0000165///MAPK cascade+++GO:0001836///release of cytochrome c from mitochondria+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007254///JNK cascade+++GO:0007258///JUN phosphorylation+++GO:0009410///response to xenobiotic stimulus+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010770///positive regulation of cell morphogenesis involved in differentiation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031175///neuron projection development+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0031396///regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032722///positive regulation of chemokine production+++GO:0034614///cellular response to reactive oxygen species+++GO:0034644///cellular response to UV+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046328///regulation of JNK cascade+++GO:0046686///response to cadmium ion+++GO:0048511///rhythmic process+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0061833///protein localization to tricellular tight junction+++GO:0071276///cellular response to cadmium ion+++GO:0071803///positive regulation of podosome assembly+++GO:1901485///positive regulation of transcription factor catabolic process+++GO:2001235///positive regulation of apoptotic signaling pathway" 26422 26422 'Nbea' mRNA 1754.24 1654.84 1491.37 9.56 8.86 8.77 4.43 3.72 4.04 9.063333333 4.063333333 1034.42 796.94 907.08 1633.483333 912.8133333 1.00E-19 -0.851644548 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0019901///protein kinase binding+++GO:0051018///protein kinase A binding GO:0006605///protein targeting+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0008104///protein localization+++GO:0061484///hematopoietic stem cell homeostasis 26423 26423 'Nr5a1' mRNA 0 2 1 0 0.04 0.02 0.03 0 0.07 0.02 0.033333333 2 0 4 1 2 0.736236787 0.987709283 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001553///luteinization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007530///sex determination+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009755///hormone-mediated signaling pathway+++GO:0009888///tissue development+++GO:0010259///multicellular organism aging+++GO:0010628///positive regulation of gene expression+++GO:0022414///reproductive process+++GO:0030154///cell differentiation+++GO:0030238///male sex determination+++GO:0030325///adrenal gland development+++GO:0030522///intracellular receptor signaling pathway+++GO:0042445///hormone metabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051457///maintenance of protein location in nucleus+++GO:0097210///response to gonadotropin-releasing hormone+++GO:0097720///calcineurin-mediated signaling+++GO:2000020///positive regulation of male gonad development+++GO:2000195///negative regulation of female gonad development" 26424 26424 'Nr5a2' mRNA 6 16 5 0.07 0.18 0.08 0.18 0.13 0.09 0.11 0.133333333 18 13 9 9 13.33333333 0.558726913 0.566975613 04950///Maturity onset diabetes of the young GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005543///phospholipid binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008206///bile acid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0009888///tissue development+++GO:0030522///intracellular receptor signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0042632///cholesterol homeostasis+++GO:0045070///positive regulation of viral genome replication+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061113///pancreas morphogenesis+++GO:0097720///calcineurin-mediated signaling+++GO:1990830///cellular response to leukemia inhibitory factor" 26425 26425 'Nubp1' mRNA 487.78 578.22 442.47 12.95 15.11 12.46 16.64 19.7 19.92 13.50666667 18.75333333 721.13 833.48 835.48 502.8233333 796.6966667 5.14E-08 0.658312622 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0001558///regulation of cell growth+++GO:0006879///cellular iron ion homeostasis+++GO:0010826///negative regulation of centrosome duplication+++GO:0016226///iron-sulfur cluster assembly+++GO:0030030///cell projection organization+++GO:0051642///centrosome localization+++GO:0072697///protein localization to cell cortex 26426 26426 'Nubp2' mRNA 1159 1098 1125 48.36 45.03 49.95 61.76 60.64 58.4 47.78 60.26666667 1695 1627 1542 1127.333333 1621.333333 5.53E-10 0.511342304 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031616///spindle pole centrosome+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0016226///iron-sulfur cluster assembly+++GO:0030030///cell projection organization 26427 26427 'Creb3l1' mRNA 87 94 71 2.15 2.29 1.86 8.09 8.11 8.67 2.1 8.29 376 368 390 84 378 1.88E-35 2.16171384 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0000139///Golgi membrane+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0046332///SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001649///osteoblast differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0007275///multicellular organism development+++GO:0010629///negative regulation of gene expression+++GO:0030278///regulation of ossification+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070278///extracellular matrix constituent secretion+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress" 26428 26428 'Orc4' mRNA 623.53 673.41 638.96 8.82 9.56 9.84 10.86 10.86 10.58 9.406666667 10.76666667 860.2 833.27 799.8 645.3 831.09 5.48E-04 0.353637741 04110///Cell cycle "GO:0000781///chromosome, telomeric region+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005730///nucleolus+++GO:0005829///cytosol" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding GO:0006260///DNA replication+++GO:0006270///DNA replication initiation 26429 26429 'Orc5' mRNA 591 587 567 16.24 15.86 16.53 12.01 13.76 11.88 16.21 12.55 503 561 480 581.6666667 514.6666667 0.152733657 -0.187365441 04110///Cell cycle GO:0000785///chromatin+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0006275///regulation of DNA replication 26430 26430 'Parg' mRNA 918 1036 784 12.01 13.1 10.35 8.66 10 11.65 11.82 10.10333333 813 881 952 912.6666667 882 0.706470371 -0.055443718 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0003682///chromatin binding+++GO:0004649///poly(ADP-ribose) glycohydrolase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0047658///alpha-amino-acid esterase activity" GO:0005975///carbohydrate metabolic process+++GO:0006282///regulation of DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0009225///nucleotide-sugar metabolic process+++GO:0016045///detection of bacterium+++GO:0031056///regulation of histone modification+++GO:0045739///positive regulation of DNA repair+++GO:1990966///ATP generation from poly-ADP-D-ribose 26431 26431 'Git2' mRNA 1358.12 1384.95 1259.94 14.48 14.49 14.3 15.28 15.51 15.06 14.42333333 15.28333333 1659 1646.13 1581 1334.336667 1628.71 3.02E-04 0.277727311 04144///Endocytosis+++05135///Yersinia infection GO:0005654///nucleoplasm+++GO:0044305///calyx of Held GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0016310///phosphorylation+++GO:0043547///positive regulation of GTPase activity+++GO:0048266///behavioral response to pain+++GO:0050790///regulation of catalytic activity+++GO:0099171///presynaptic modulation of chemical synaptic transmission+++GO:2000300///regulation of synaptic vesicle exocytosis 26432 26432 'Plod2' mRNA 1444 1479 897 19.62 19.5 12.62 14.77 19.86 18.59 17.24666667 17.74 1194 1551 1459 1273.333333 1401.333333 0.655860993 0.140256946 00310///Lysine degradation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030867///rough endoplasmic reticulum membrane "GO:0005506///iron ion binding+++GO:0008475///procollagen-lysine 5-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001666///response to hypoxia+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0046947///hydroxylysine biosynthetic process 26433 26433 'Plod3' mRNA 1398.35 1310.49 1368.26 23.29 21.48 24.18 35.9 34.26 34.96 22.98333333 35.04 2479.74 2311.54 2338.86 1359.033333 2376.713333 2.51E-26 0.792919403 00310///Lysine degradation+++00514///Other types of O-glycan biosynthesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix "GO:0003824///catalytic activity+++GO:0005506///iron ion binding+++GO:0008475///procollagen-lysine 5-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0031418///L-ascorbic acid binding+++GO:0033823///procollagen glucosyltransferase activity+++GO:0046872///metal ion binding+++GO:0050211///procollagen galactosyltransferase activity+++GO:0051213///dioxygenase activity" GO:0001701///in utero embryonic development+++GO:0001886///endothelial cell morphogenesis+++GO:0006493///protein O-linked glycosylation+++GO:0008104///protein localization+++GO:0008152///metabolic process+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0021915///neural tube development+++GO:0030199///collagen fibril organization+++GO:0032870///cellular response to hormone stimulus+++GO:0032963///collagen metabolic process+++GO:0042311///vasodilation+++GO:0046947///hydroxylysine biosynthetic process+++GO:0048730///epidermis morphogenesis+++GO:0060425///lung morphogenesis+++GO:0070831///basement membrane assembly 26434 26434 'Prnd' mRNA 2 3 3 0.06 0.09 0.09 0.91 0.97 1.28 0.08 1.053333333 45 43 64 2.666666667 50.66666667 7.00E-10 4.236574458 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006878///cellular copper ion homeostasis+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0007340///acrosome reaction+++GO:0051260///protein homooligomerization 26436 26436 'Psg16' mRNA 799.07 824.82 671.04 9.66 9.67 8.48 7.69 7.59 8.26 9.27 7.846666667 731.99 713.11 761.54 764.9766667 735.5466667 0.616702882 -0.065371051 GO:0009986///cell surface GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0008150///biological_process 26437 26437 'Psg17' mRNA 1 0 4 0.03 0 0.12 0 0.07 0.15 0.05 0.073333333 0 3 6 1.666666667 3 0.747133847 0.804256821 GO:0005515///protein binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0006909///phagocytosis+++GO:0006955///immune response+++GO:0007565///female pregnancy 26439 26439 'Psg19' mRNA 0 1 0 0 0.02 0 0.04 0.02 0 0.006666667 0.02 2 1 0 0.333333333 1 0.735918097 1.457602817 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0008150///biological_process 26440 26440 'Psma1' mRNA 2979 3248 3070 144.54 155.59 158.04 195.58 199.18 194.25 152.7233333 196.3366667 4627 4596 4444 3099 4555.666667 5.02E-18 0.543873889 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex" GO:0001530///lipopolysaccharide binding+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway+++GO:0007584///response to nutrient+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:2000427///positive regulation of apoptotic cell clearance" 26441 26441 'Psma4' mRNA 1597.95 1566.91 1505 90.31 87.81 90.16 140.5 139.23 134.82 89.42666667 138.1833333 2845.91 2744 2644.97 1556.62 2744.96 2.05E-33 0.806900104 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0000932///P-body+++GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0043231///intracellular membrane-bounded organelle" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity "GO:0001906///cell killing+++GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006955///immune response+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0007596///blood coagulation+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0019835///cytolysis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0051260///protein homooligomerization+++GO:0051603///proteolysis involved in cellular protein catabolic process" 26442 26442 'Psma5' mRNA 1913 1885 1715 96.28 93.68 91.58 138.88 142.89 133.96 93.84666667 138.5766667 3167 3178 2954 1837.666667 3099.666667 2.57E-29 0.743994545 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex" GO:0004175///endopeptidase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 26443 26443 'Psma6' mRNA 1796 1690 1710 115.26 107.26 116.44 166.43 162.3 166.41 112.9866667 165.0466667 2973 2826 2873 1732 2890.666667 1.12E-26 0.726398684 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0005844///polysome+++GO:0016363///nuclear matrix+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0030016///myofibril+++GO:0030017///sarcomere" GO:0003723///RNA binding+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0051059///NF-kappaB binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007519///skeletal muscle tissue development+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051603///proteolysis involved in cellular protein catabolic process 26444 26444 'Psma7' mRNA 3288 3361 3401 221.82 224.25 244.93 291.57 300.63 289.6 230.3333333 293.9333333 4924 4956 4729 3350 4869.666667 4.38E-16 0.526653386 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0098794///postsynapse" GO:0004175///endopeptidase activity+++GO:0042802///identical protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 26445 26445 'Psmb2' mRNA 2663 2672 2622 210.73 209.29 220.11 292.26 293.68 285.08 213.3766667 290.34 4230 4142 3986 2652.333333 4119.333333 4.30E-24 0.6228526 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity GO:0010243///response to organonitrogen compound+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0014070///response to organic cyclic compound+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 26446 26446 'Psmb3' mRNA 2871 2866 2878 276.07 273.5 293.71 361.9 381.34 350.89 281.0933333 364.71 4304 4414 4027 2871.666667 4248.333333 2.52E-16 0.552521353 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0030163///protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 26447 26447 'Poli' mRNA 396 448.22 411.01 6.36 6.94 7.23 4.02 4.42 3.92 6.843333333 4.12 242.04 289.08 240 418.41 257.04 1.71E-06 -0.713108078 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019985///translesion synthesis+++GO:0071494///cellular response to UV-C+++GO:0071897///DNA biosynthetic process 26448 26448 'Mok' mRNA 512.8 548.08 500.39 18.32 18.89 19.35 5.59 4.55 4.85 18.85333333 4.996666667 192.35 152.55 145.92 520.4233333 163.6066667 7.74E-31 -1.686464237 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0051726///regulation of cell cycle 26450 26450 'Rbbp9' mRNA 1262 1300 1258 33 33.48 34.89 23.19 20.54 22.81 33.79 22.18 1020 882 971 1273.333333 957.6666667 1.53E-06 -0.424054064 GO:0005654///nucleoplasm GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0042127///regulation of cell proliferation 26451 26451 'Rpl27a' mRNA 2360.59 2160.43 2156 132.44 119.77 128.35 159.83 158.67 173.81 126.8533333 164.1033333 3267.99 3163.39 3435.53 2225.673333 3288.97 2.43E-15 0.551601534 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 26456 26456 'Sema4g' mRNA 173 175 157 2.11 2.13 2.02 1.23 1.63 1.73 2.086666667 1.53 114 150 155 168.3333333 139.6666667 0.249477193 -0.277108929 04360///Axon guidance GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity GO:0001755///neural crest cell migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway 26457 26457 'Slc27a1' mRNA 6010.72 5994.49 6035.19 96.44 95.07 103.6 74.43 76.7 76.49 98.37 75.87333333 5251.1 5289.75 5223.41 6013.466667 5254.753333 8.47E-04 -0.207239959 03320///PPAR signaling pathway+++04931///Insulin resistance+++04975///Fat digestion and absorption GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009925///basal plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005515///protein binding+++GO:0015225///biotin transmembrane transporter activity+++GO:0015245///fatty acid transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0042802///identical protein binding+++GO:0047676///arachidonate-CoA ligase activity+++GO:0090434///oleoyl-CoA ligase activity+++GO:1901480///oleate transmembrane transporter activity GO:0001579///medium-chain fatty acid transport+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006869///lipid transport+++GO:0009409///response to cold+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0015878///biotin transport+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0031652///positive regulation of heat generation+++GO:0032049///cardiolipin biosynthetic process+++GO:0032868///response to insulin+++GO:0033211///adiponectin-activated signaling pathway+++GO:0044381///glucose import in response to insulin stimulus+++GO:0044539///long-chain fatty acid import+++GO:0071072///negative regulation of phospholipid biosynthetic process+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0140115///export across plasma membrane+++GO:1905135///biotin import across plasma membrane+++GO:1990379///lipid transport across blood brain barrier 26458 26458 'Slc27a2' mRNA 324 357 395 7.9 8.58 10.22 4.73 5.08 4.34 8.9 4.716666667 223 234 198 358.6666667 218.3333333 1.04E-05 -0.731583117 03320///PPAR signaling pathway+++04146///Peroxisome+++04931///Insulin resistance GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005524///ATP binding+++GO:0015245///fatty acid transmembrane transporter activity+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047676///arachidonate-CoA ligase activity+++GO:0047747///cholate-CoA ligase activity+++GO:0050197///phytanate-CoA ligase activity+++GO:0070251///pristanate-CoA ligase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001561///fatty acid alpha-oxidation+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006699///bile acid biosynthetic process+++GO:0015908///fatty acid transport+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0044539///long-chain fatty acid import+++GO:0097089///methyl-branched fatty acid metabolic process 26459 26459 'Slc27a5' mRNA 2 1 4 0.05 0.02 0.1 0.06 0.02 0.04 0.056666667 0.04 3 1 2 2.333333333 2 0.898735771 -0.264344399 00120///Primary bile acid biosynthesis+++03320///PPAR signaling pathway+++04931///Insulin resistance+++04976///Bile secretion GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005524///ATP binding+++GO:0015245///fatty acid transmembrane transporter activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0044877///protein-containing complex binding+++GO:0047747///cholate-CoA ligase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006642///triglyceride mobilization+++GO:0006699///bile acid biosynthetic process+++GO:0008206///bile acid metabolic process+++GO:0015908///fatty acid transport+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0046951///ketone body biosynthetic process 26462 26462 'Txnrd2' mRNA 545.18 560.17 562 16.38 16.6 17.94 14.95 16.14 13.24 16.97333333 14.77666667 569.14 601.28 489.12 555.7833333 553.18 0.903710798 -0.019457398 00450///Selenocompound metabolism+++05200///Pathways in cancer+++05225///Hepatocellular carcinoma GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0000305///response to oxygen radical+++GO:0007507///heart development+++GO:0030097///hemopoiesis+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification 26464 26464 'Vnn3' mRNA 6 8 5 0.19 0.25 0.17 0.11 0.23 0.09 0.203333333 0.143333333 4 8 3 6.333333333 5 0.810975795 -0.341200411 00770///Pantothenate and CoA biosynthesis GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane "GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0017159///pantetheine hydrolase activity" GO:0006807///nitrogen compound metabolic process+++GO:0015939///pantothenate metabolic process 26465 26465 'Zfp146' mRNA 99 73 62 1.93 1.4 1.28 1.43 0.95 1.47 1.536666667 1.283333333 85 55 84 78 74.66666667 0.863090843 -0.072478928 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 26466 26466 'Zfp260' mRNA 1347 1420 1568 19.67 20.4 24.33 19.01 18.16 17.96 21.46666667 18.37666667 1497 1396 1369 1445 1420.666667 0.755049309 -0.040661933 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development 264895 264895 'Acsf2' mRNA 768 681 451 13.72 11.98 8.55 7 6.41 6.54 11.41666667 6.65 451 403 408 633.3333333 420.6666667 1.41E-04 -0.59374699 GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0031956///medium-chain fatty acid-CoA ligase activity+++GO:0047760///butyrate-CoA ligase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process 26549 26549 'Itgb1bp2' mRNA 205.53 179.58 252.03 0.89 0.77 1.32 0.75 0.8 0.8 0.993333333 0.783333333 235.82 198.53 205.65 212.38 213.3333333 0.954184132 -0.015994685 GO:0030018///Z disc GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding 26554 26554 'Cul3' mRNA 782 746 763 10.25 9.6 10.6 8.94 9 9.69 10.15 9.21 781 765 802 763.6666667 782.6666667 0.863090843 0.022954225 04120///Ubiquitin mediated proteolysis+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005827///polar microtubule+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0072686///mitotic spindle GO:0004842///ubiquitin-protein transferase activity+++GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0030332///cyclin binding+++GO:0031208///POZ domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0000278///mitotic cell cycle+++GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001831///trophectodermal cellular morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0007229///integrin-mediated signaling pathway+++GO:0007369///gastrulation+++GO:0016055///Wnt signaling pathway+++GO:0016192///vesicle-mediated transport+++GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0017145///stem cell division+++GO:0030030///cell projection organization+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032467///positive regulation of cytokinesis+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0040016///embryonic cleavage+++GO:0043149///stress fiber assembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044346///fibroblast apoptotic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0048208///COPII vesicle coating+++GO:0051301///cell division+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0071630///nuclear protein quality control by the ubiquitin-proteasome system+++GO:0072576///liver morphogenesis+++GO:1901992///positive regulation of mitotic cell cycle phase transition 26556 26556 'Homer1' mRNA 349 393 356 2.42 2.63 2.73 1.41 1.34 1.64 2.593333333 1.463333333 214 201 217 366 210.6666667 5.64E-08 -0.808356094 04068///FoxO signaling pathway+++04724///Glutamatergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043034///costamere+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044309///neuron spine+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0035256///G protein-coupled glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity+++GO:0097110///scaffold protein binding+++GO:0099186///structural constituent of postsynapse "GO:0003009///skeletal muscle contraction+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0035418///protein localization to synapse+++GO:0048148///behavioral response to cocaine+++GO:0048741///skeletal muscle fiber development+++GO:0048875///chemical homeostasis within a tissue+++GO:0051262///protein tetramerization+++GO:0051592///response to calcium ion+++GO:0051928///positive regulation of calcium ion transport+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0090279///regulation of calcium ion import+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099173///postsynapse organization+++GO:1902950///regulation of dendritic spine maintenance+++GO:2001256///regulation of store-operated calcium entry+++GO:2001257///regulation of cation channel activity" 26557 26557 'Homer2' mRNA 423 457 270 2.01 2.14 1.36 0.52 0.43 0.52 1.836666667 0.49 126 102 123 383.3333333 117 1.36E-18 -1.714941195 04068///FoxO signaling pathway+++04724///Glutamatergic synapse GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043229///intracellular organelle+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0030160///GKAP/Homer scaffold activity+++GO:0035254///glutamate receptor binding+++GO:0035256///G protein-coupled glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032703///negative regulation of interleukin-2 production+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0048148///behavioral response to cocaine+++GO:0048875///chemical homeostasis within a tissue+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:2001256///regulation of store-operated calcium entry 26558 26558 'Homer3' mRNA 274.79 282.08 153.65 6.26 6.32 3.72 6.22 9.32 7.85 5.433333333 7.796666667 315.83 458.58 384.12 236.84 386.1766667 7.81E-04 0.710002845 04068///FoxO signaling pathway+++04724///Glutamatergic synapse GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0045178///basal part of cell+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0035256///G protein-coupled glutamate receptor binding+++GO:0042802///identical protein binding GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0032703///negative regulation of interleukin-2 production+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:2001256///regulation of store-operated calcium entry 26559 26559 'Hunk' mRNA 357 357 287 3.74 3.7 3.19 1.37 1.2 1.2 3.543333333 1.256666667 152 130 126 333.6666667 136 9.30E-15 -1.3037862 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 26561 26561 'Mmp23' mRNA 106 103 94 4.31 4.12 4.06 12.24 10.5 9.96 4.163333333 10.9 342 289 267 101 299.3333333 2.87E-17 1.555362276 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000003///reproduction+++GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process 26562 26562 'Ncdn' mRNA 2548.04 2614.89 2532 39.15 39.81 41.84 21.88 21.02 21.99 40.26666667 21.63 1634.71 1509 1588.16 2564.976667 1577.29 2.43E-25 -0.714170104 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0005515///protein binding GO:0031175///neuron projection development+++GO:0045453///bone resorption+++GO:0048168///regulation of neuronal synaptic plasticity 26563 26563 'Ror1' mRNA 1391 1392 1249 17.79 16.78 14.78 11.4 12.4 12.95 16.45 12.25 1115 1111 1190 1344 1138.666667 0.003502373 -0.24905164 04310///Wnt signaling pathway GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0043679///axon terminus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0017147///Wnt-protein binding+++GO:0042813///Wnt-activated receptor activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0010976///positive regulation of neuron projection development+++GO:0014002///astrocyte development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016055///Wnt signaling pathway+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0048839///inner ear development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 26564 26564 'Ror2' mRNA 122 138 42 1.65 1.84 0.6 0.18 0.36 0.47 1.363333333 0.336666667 15 30 39 100.6666667 28 3.92E-05 -1.831019743 04310///Wnt signaling pathway GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017147///Wnt-protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0046872///metal ion binding "GO:0001501///skeletal system development+++GO:0001502///cartilage condensation+++GO:0001756///somitogenesis+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0007224///smoothened signaling pathway+++GO:0007254///JNK cascade+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0014002///astrocyte development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0030335///positive regulation of cell migration+++GO:0030509///BMP signaling pathway+++GO:0030538///embryonic genitalia morphogenesis+++GO:0030539///male genitalia development+++GO:0033674///positive regulation of kinase activity+++GO:0042472///inner ear morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045165///cell fate commitment+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900020///positive regulation of protein kinase C activity+++GO:1905517///macrophage migration" 26565 26565 'Pla2g10' mRNA 5 4 1 0.35 0.25 0.07 0.06 0.13 0 0.223333333 0.063333333 1 2 0 3.333333333 1 0.413685822 -1.722982519 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle "GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0001516///prostaglandin biosynthetic process+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0007411///axon guidance+++GO:0009566///fertilization+++GO:0010884///positive regulation of lipid storage+++GO:0016042///lipid catabolic process+++GO:0031069///hair follicle morphogenesis+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034638///phosphatidylcholine catabolic process+++GO:0036335///intestinal stem cell homeostasis+++GO:0042116///macrophage activation+++GO:0042632///cholesterol homeostasis+++GO:0043030///regulation of macrophage activation+++GO:0043249///erythrocyte maturation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0046337///phosphatidylethanolamine metabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0050482///arachidonic acid secretion+++GO:0050728///negative regulation of inflammatory response+++GO:0051607///defense response to virus+++GO:0051977///lysophospholipid transport+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0090370///negative regulation of cholesterol efflux+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000344///positive regulation of acrosome reaction 26568 26568 'Slc27a3' mRNA 83 71 40 1.65 1.44 0.85 1.44 2.02 2.2 1.313333333 1.886666667 76 99 109 64.66666667 94.66666667 0.10989327 0.551663822 04931///Insulin resistance GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0004321///fatty-acyl-CoA synthase activity+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047676///arachidonate-CoA ligase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport 26569 26569 'Slc27a4' mRNA 567 580 335 7.54 7.59 4.73 5.21 7.37 6.62 6.62 6.4 451 623 555 494 543 0.524878086 0.13895052 03320///PPAR signaling pathway+++04931///Insulin resistance+++04975///Fat digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047676///arachidonate-CoA ligase activity+++GO:0090433///palmitoyl-CoA ligase activity+++GO:0090434///oleoyl-CoA ligase activity+++GO:1901480///oleate transmembrane transporter activity "GO:0000038///very long-chain fatty acid metabolic process+++GO:0001579///medium-chain fatty acid transport+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006869///lipid transport+++GO:0007584///response to nutrient+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043588///skin development+++GO:0044381///glucose import in response to insulin stimulus+++GO:0044539///long-chain fatty acid import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0062003///negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity+++GO:0090630///activation of GTPase activity+++GO:1990379///lipid transport across blood brain barrier" 26570 26570 'Slc7a11' mRNA 3153.4 3074.08 2875.12 17.92 17.18 17.34 27.17 23.83 25.62 17.48 25.54 5502.62 4716.43 5029.01 3034.2 5082.686667 7.79E-32 0.732135084 04216///Ferroptosis GO:0005791///rough endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0097449///astrocyte projection GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006749///glutathione metabolic process+++GO:0006865///amino acid transport+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0008542///visual learning+++GO:0009636///response to toxic substance+++GO:0014070///response to organic cyclic compound+++GO:0021591///ventricular system development+++GO:0021756///striatum development+++GO:0030534///adult behavior+++GO:0033029///regulation of neutrophil apoptotic process+++GO:0033554///cellular response to stress+++GO:0034599///cellular response to oxidative stress+++GO:0034775///glutathione transmembrane transport+++GO:0035094///response to nicotine+++GO:0042127///regulation of cell proliferation+++GO:0048021///regulation of melanin biosynthetic process+++GO:0048286///lung alveolus development+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050807///regulation of synapse organization+++GO:0051223///regulation of protein transport+++GO:0051775///response to redox state+++GO:0055085///transmembrane transport+++GO:0060173///limb development+++GO:0070306///lens fiber cell differentiation+++GO:0070527///platelet aggregation+++GO:0071702///organic substance transport+++GO:0090461///glutamate homeostasis+++GO:0098712///L-glutamate import across plasma membrane+++GO:0140206///dipeptide import across plasma membrane+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1901494///regulation of cysteine metabolic process+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903786///regulation of glutathione biosynthetic process+++GO:1904717///regulation of AMPA glutamate receptor clustering+++GO:2000211///regulation of glutamate metabolic process 26572 26572 'Cops3' mRNA 1377.01 1493.03 1506.01 50.62 54 58.79 50.07 51.41 53.46 54.47 51.64666667 1558.01 1562 1608.01 1458.683333 1576.006667 0.323017495 0.098401808 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008180///COP9 signalosome GO:0003674///molecular_function+++GO:0005515///protein binding GO:0000338///protein deneddylation+++GO:0001701///in utero embryonic development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007595///lactation+++GO:0050821///protein stabilization 26611 26611 'Rcn2' mRNA 6527 6704 6677 182.57 184.3 197.93 151.98 148.44 147.49 188.2666667 149.3033333 6251 5957 5876 6636 6028 0.015097637 -0.151901867 GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding 266614 266614 'Ly6g5b' mRNA 57.8 63.78 73.37 0.72 0.78 0.97 1.16 1.32 1.17 0.823333333 1.216666667 102.01 100.36 104.63 64.98333333 102.3333333 0.024357316 0.649153973 GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0032991///protein-containing complex GO:0042802///identical protein binding 266632 266632 'Irak4' mRNA 461 448 491 9.16 8.86 10.41 17.83 15.98 16.57 9.476666667 16.79333333 1036 911 931 466.6666667 959.3333333 1.46E-21 1.024572046 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04722///Neurotrophin signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding GO:0001816///cytokine production+++GO:0002376///immune system process+++GO:0002446///neutrophil mediated immunity+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0016310///phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:1990266///neutrophil migration 266645 266645 'Acmsd' mRNA 9.09 6.99 6.96 0.22 0.17 0.18 0.09 0.13 0.06 0.19 0.093333333 4.23 5.88 2.87 7.68 4.326666667 0.457340331 -0.941187035 00380///Tryptophan metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001760///aminocarboxymuconate-semialdehyde decarboxylase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0046872///metal ion binding GO:0006569///tryptophan catabolic process+++GO:0007568///aging+++GO:0019748///secondary metabolic process+++GO:0046874///quinolinate metabolic process+++GO:1904985///negative regulation of quinolinate biosynthetic process 266690 266690 'Cyb5r4' mRNA 601 591 463 14.11 13.35 11.15 17.46 22.43 19.71 12.87 19.86666667 882 1092 944 551.6666667 972.6666667 1.25E-11 0.813043254 00520///Amino sugar and nucleotide sugar metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0003958///NADPH-hemoprotein reductase activity+++GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0005515///protein binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016653///oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0006091///generation of precursor metabolites and energy+++GO:0006739///NADP metabolic process+++GO:0006801///superoxide metabolic process+++GO:0030073///insulin secretion+++GO:0042168///heme metabolic process+++GO:0042593///glucose homeostasis+++GO:0046677///response to antibiotic+++GO:0048468///cell development+++GO:0072593///reactive oxygen species metabolic process 266692 266692 'Cpne1' mRNA 1121.97 1096.46 1005.51 17.55 16.83 16.64 19.47 18.9 17.83 17.00666667 18.73333333 1434.63 1359.33 1272.53 1074.646667 1355.496667 1.37E-04 0.324373876 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0001786///phosphatidylserine binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004175///endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding GO:0006508///proteolysis+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043392///negative regulation of DNA binding+++GO:0045666///positive regulation of neuron differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071277///cellular response to calcium ion+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1990138///neuron projection extension 266781 266781 'Snx17' mRNA 2038 2032 2019 59.7 58.47 62.62 72.11 66.21 69.9 60.26333333 69.40666667 2830 2538 2654 2029.666667 2674 3.40E-08 0.384532015 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0006886///intracellular protein transport+++GO:0006898///receptor-mediated endocytosis+++GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0035904///aorta development+++GO:0060976///coronary vasculature development 266815 266815 'Mill1' mRNA 15 16 18 0.34 0.49 0.44 0.06 0.07 0.13 0.423333333 0.086666667 3 3 6 16.33333333 4 0.016444089 -2.044440271 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane GO:0005515///protein binding GO:0006955///immune response 267019 267019 'Rps15a' mRNA 1368.51 1323.01 1415.7 14.22 13.52 15.6 20.61 20.95 22.35 14.44666667 21.30333333 2283.39 2268.23 2398.91 1369.073333 2316.843333 9.92E-21 0.745515743 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008284///positive regulation of cell proliferation+++GO:0009615///response to virus+++GO:0045787///positive regulation of cell cycle 26754 26754 'Cops5' mRNA 924.96 994 880.99 30.95 33.42 31.27 39.55 39.99 39.59 31.88 39.71 1317.98 1326 1306 933.3166667 1316.66 5.29E-09 0.486888781 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0008180///COP9 signalosome+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003713///transcription coactivator activity+++GO:0004222///metalloendopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0019784///NEDD8-specific protease activity+++GO:0019899///enzyme binding+++GO:0035718///macrophage migration inhibitory factor binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity "GO:0000338///protein deneddylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046328///regulation of JNK cascade+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:1903894///regulation of IRE1-mediated unfolded protein response+++GO:1990182///exosomal secretion" 26757 26757 'Dpysl4' mRNA 275 318 237 5.71 6.55 5.23 1.94 1.83 2.07 5.83 1.946666667 107 99 112 276.6666667 106 8.20E-14 -1.39157453 GO:0005737///cytoplasm "GO:0004157///dihydropyrimidinase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding+++GO:0051219///phosphoprotein binding" GO:0006208///pyrimidine nucleobase catabolic process+++GO:0070997///neuron death+++GO:0097485///neuron projection guidance 268281 268281 'Shprh' mRNA 952.58 997.74 923.27 6.49 6.69 6.69 4.77 5.14 4.89 6.623333333 4.933333333 793.87 829.41 795.11 957.8633333 806.13 0.007208183 -0.25953371 GO:0000786///nucleosome+++GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006334///nucleosome assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination 268288 268288 'Samd3' mRNA 0 4 1 0 0.09 0.03 0.13 0.05 0.22 0.04 0.133333333 5 2 9 1.666666667 5.333333333 0.320575642 1.679109283 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 268291 268291 'Rnf217' mRNA 46 35 41 0.89 0.66 0.84 1.16 0.84 1.11 0.796666667 1.036666667 69 49 64 40.66666667 60.66666667 0.146452127 0.561551791 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 268294 268294 'Zbtb24' mRNA 572.24 575.95 453.09 11.16 11.05 9.36 8.79 7.62 8.6 10.52333333 8.336666667 514.01 435.01 487.93 533.76 478.9833333 0.242672069 -0.164629197 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 268297 268297 'Scml4' mRNA 197 210 204 2.37 2.44 2.58 2.08 2.05 1.99 2.463333333 2.04 188 200 179 203.6666667 189 0.599526631 -0.119601622 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding "GO:0045892///negative regulation of transcription, DNA-templated" 268301 268301 'Sowahc' mRNA 375 352 334 4.46 4.12 4.21 5.38 5.62 5.25 4.263333333 5.416666667 521 532 492 353.6666667 515 2.25E-05 0.531562128 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 268345 268345 'Kcnc2' mRNA 101 103 96 1.1 1.09 1.12 0.05 0.18 0.08 1.103333333 0.103333333 5 16 9 100 10 1.31E-15 -3.328849591 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031982///vesicle+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0001508///action potential+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0009636///response to toxic substance+++GO:0009642///response to light intensity+++GO:0014070///response to organic cyclic compound+++GO:0014075///response to amine+++GO:0021759///globus pallidus development+++GO:0032026///response to magnesium ion+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0038060///nitric oxide-cGMP-mediated signaling pathway+++GO:0045471///response to ethanol+++GO:0051260///protein homooligomerization+++GO:0051291///protein heterooligomerization+++GO:0055085///transmembrane transport+++GO:0071242///cellular response to ammonium ion+++GO:0071732///cellular response to nitric oxide+++GO:0071805///potassium ion transmembrane transport+++GO:0097237///cellular response to toxic substance+++GO:0099505///regulation of presynaptic membrane potential+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity+++GO:1990089///response to nerve growth factor 268354 268354 'Tafa2' mRNA 154.78 195.98 166.39 1.61 1.93 1.86 0.41 0.22 0.18 1.8 0.27 55.77 36.15 26.35 172.3833333 39.42333333 2.24E-14 -2.152466906 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0007613///memory+++GO:0008542///visual learning 268373 268373 'Ppia' mRNA 20879.64 21415.59 20237.57 1952.88 1987.23 2008.81 3121.03 3348.5 3240.13 1982.973333 3236.553333 38168.59 39860.64 38243.04 20844.26667 38757.42333 1.17E-69 0.883856389 04217///Necroptosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:1904399///heparan sulfate binding GO:0000187///activation of MAPK activity+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006457///protein folding+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0030168///platelet activation+++GO:0030182///neuron differentiation+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0032148///activation of protein kinase B activity+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0034389///lipid droplet organization+++GO:0034599///cellular response to oxidative stress+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0042118///endothelial cell activation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045069///regulation of viral genome replication+++GO:0045070///positive regulation of viral genome replication+++GO:0050714///positive regulation of protein secretion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060352///cell adhesion molecule production+++GO:0061944///negative regulation of protein K48-linked ubiquitination+++GO:0070527///platelet aggregation+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903901///negative regulation of viral life cycle+++GO:2001233///regulation of apoptotic signaling pathway 268379 268379 'Abca13' mRNA 1892 1859 1733 6.62 6.36 6.46 1.51 1.09 1.24 6.48 1.28 502 350 395 1828 415.6666667 1.33E-93 -2.150341383 02010///ABC transporters GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097708///intracellular vesicle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0035627///ceramide transport+++GO:0055085///transmembrane transport+++GO:1900244///positive regulation of synaptic vesicle endocytosis 268390 268390 'Ahsa2' mRNA 1067.51 1142.52 1104.84 26.71 28.22 28.31 23.52 20.91 21.87 27.74666667 22.1 1148.65 1048.43 1106.14 1104.956667 1101.073333 0.876412369 -0.017678608 GO:0005829///cytosol GO:0001671///ATPase activator activity+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0006457///protein folding+++GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity 268395 268395 'Mpg' mRNA 338.02 350.54 310.71 11.21 11.46 10.93 13.34 14.57 12.68 11.2 13.53 462.52 492.92 425.36 333.09 460.2666667 7.10E-04 0.456810505 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0042645///mitochondrial nucleoid GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0003905///alkylbase DNA N-glycosylase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0008725///DNA-3-methyladenine glycosylase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043916///DNA-7-methylguanine glycosylase activity+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding+++GO:0052821///DNA-7-methyladenine glycosylase activity+++GO:0052822///DNA-3-methylguanine glycosylase activity GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0035372///protein localization to microtubule 268396 268396 'Sh3pxd2b' mRNA 582 584 492 4.14 4.09 3.71 7.08 7.28 7.12 3.98 7.16 1146 1151 1116 552.6666667 1137.666667 2.15E-28 1.03271462 GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042995///cell projection "GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0042169///SH2 domain binding+++GO:0060090///molecular adaptor activity+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0001501///skeletal system development+++GO:0001654///eye development+++GO:0002051///osteoblast fate commitment+++GO:0006801///superoxide metabolic process+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0022617///extracellular matrix disassembly+++GO:0030154///cell differentiation+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042554///superoxide anion generation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0048705///skeletal system morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060348///bone development+++GO:0060378///regulation of brood size+++GO:0060612///adipose tissue development+++GO:0071800///podosome assembly+++GO:0072657///protein localization to membrane+++GO:1904179///positive regulation of adipose tissue development+++GO:1904888///cranial skeletal system development 268417 268417 'Zkscan17' mRNA 792 753 696 11.23 10.49 11.26 7.86 7.52 7.4 10.99333333 7.593333333 617 574 571 747 587.3333333 6.40E-04 -0.357822793 GO:0005634///nucleus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 268420 268420 'Alkbh5' mRNA 3975.44 3924.96 4136.47 35.01 33.98 38.64 29.62 29.07 29.57 35.87666667 29.42 3873.4 3713.69 3745.45 4012.29 3777.513333 0.18986917 -0.101132338 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0004622///lysophospholipase activity+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0035515///oxidative RNA demethylase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:1990931///RNA N6-methyladenosine dioxygenase activity" GO:0001666///response to hypoxia+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0035553///oxidative single-stranded RNA demethylation+++GO:0043488///regulation of mRNA stability 268445 268445 'Ankrd13b' mRNA 226 259 227 3.25 3.8 3.52 2.47 2.16 2.23 3.523333333 2.286666667 189 163 167 237.3333333 173 0.010291724 -0.467865275 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0140036///ubiquitin-dependent protein binding GO:0002091///negative regulation of receptor internalization 268448 268448 'Phf12' mRNA 479 459 399 6.2 5.87 5.51 4.93 4.99 5.45 5.86 5.123333333 440 427 466 445.6666667 444.3333333 0.936365601 -0.013478872 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016580///Sin3 complex+++GO:0017053///transcriptional repressor complex+++GO:0070822///Sin3-type complex GO:0001222///transcription corepressor binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated" 268449 268449 'Rpl23a' mRNA 2228.99 2119.08 2049.65 315.37 299 307.85 412.91 452.04 433.28 307.4066667 432.7433333 3325.6 3536.2 3360.78 2132.573333 3407.526667 1.01E-22 0.665634079 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0019843///rRNA binding+++GO:0070180///large ribosomal subunit rRNA binding+++GO:1904841///TORC2 complex binding GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation+++GO:0008150///biological_process 268451 268451 'Rab11fip4' mRNA 2327 2357 1856 17.98 17.71 15.1 7.7 6.7 7.01 16.93 7.136666667 1155 986 1023 2180 1054.666667 1.55E-34 -1.055963829 04144///Endocytosis GO:0005768///endosome+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane GO:0005509///calcium ion binding+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0003407///neural retina development+++GO:0007049///cell cycle+++GO:0032456///endocytic recycling+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division+++GO:1903452///positive regulation of G1 to G0 transition 268465 268465 'Eme1' mRNA 1.06 8.4 3.12 0.04 0.34 0.09 1.06 1.25 1.12 0.156666667 1.143333333 48.98 56.42 50.19 4.193333333 51.86333333 4.05E-09 3.677488407 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0048476///Holliday junction resolvase complex GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000712///resolution of meiotic recombination intermediates+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0031573///intra-S DNA damage checkpoint+++GO:0072429///response to intra-S DNA damage checkpoint signaling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 268469 268469 'Zfp652' mRNA 96 82 68 1.99 1.68 1.5 1.77 1.7 1.9 1.723333333 1.79 98 92 102 82 97.33333333 0.44757702 0.239447721 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 268470 268470 'Ube2z' mRNA 630 620 565 8.56 8.29 8.14 12.17 10.98 10.91 8.33 11.35333333 1031 909 895 605 945 1.38E-10 0.631921784 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016567///protein ubiquitination+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process 268480 268480 'Rapgefl1' mRNA 424 432 273 5.76 5.77 3.96 1.09 0.93 0.9 5.163333333 0.973333333 91 76 75 376.3333333 80.66666667 8.13E-29 -2.225875722 GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 268481 268481 'Krt222' mRNA 343 319 315 5.9 5.37 5.72 0.47 0.28 0.23 5.663333333 0.326666667 32 18 15 325.6666667 21.66666667 1.14E-52 -3.924123405 GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 268490 268490 'Lsm12' mRNA 561 553 478 20.93 20.83 19.46 28.57 29.36 27.92 20.40666667 28.61666667 886 826 801 530.6666667 837.6666667 2.09E-10 0.64863914 04711///Circadian rhythm - fly GO:0005575///cellular_component GO:0003674///molecular_function 268491 268491 'Meioc' mRNA 8 2 5 0.09 0.04 0.06 0.03 0.03 0.03 0.063333333 0.03 2 2 3 5 2.333333333 0.473780066 -1.114613319 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding "GO:0006302///double-strand break repair+++GO:0007130///synaptonemal complex assembly+++GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0048255///mRNA stabilization+++GO:0048599///oocyte development+++GO:0051310///metaphase plate congression+++GO:0051321///meiotic cell cycle+++GO:0051729///germline cell cycle switching, mitotic to meiotic cell cycle+++GO:0070192///chromosome organization involved in meiotic cell cycle" 268510 268510 'Mgat5b' mRNA 266 250 259 3.79 3.49 3.87 0.59 0.29 0.26 3.716666667 0.38 48 23 20 258.3333333 30.33333333 6.88E-31 -3.10802171 00510///N-Glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030144///alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0018242///protein O-linked glycosylation via serine 268512 268512 'Slc26a11' mRNA 257 260 252 5.21 5.14 5.46 9.91 9.31 8.64 5.27 9.286666667 551 520 474 256.3333333 515 4.02E-14 0.994257272 GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity GO:0006811///ion transport+++GO:0008272///sulfate transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport 268515 268515 'Bahcc1' mRNA 294 303 218 1.42 1.44 1.13 0.79 0.67 0.84 1.33 0.766666667 187 155 193 271.6666667 178.3333333 8.73E-04 -0.614057551 GO:0003682///chromatin binding 268527 268527 'Greb1' mRNA 30 29 25 0.2 0.19 0.18 0.9 0.75 0.72 0.19 0.79 137 124 123 28 128 9.84E-14 2.182193809 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007275///multicellular organism development 268534 268534 'Sntg2' mRNA 7 6 3 0.17 0.14 0.08 0.13 0.08 0.22 0.13 0.143333333 6 4 10 5.333333333 6.666666667 0.820100759 0.321204581 GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0016020///membrane+++GO:0042383///sarcolemma GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0097109///neuroligin family protein binding 268564 268564 'Zbtb1' mRNA 751.02 868 741.01 8.48 9.42 7.92 10.25 9.15 9.96 8.606666667 9.786666667 988.54 842.95 935.7 786.6766667 922.3966667 0.04242095 0.217228896 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016604///nuclear body+++GO:0031965///nuclear membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002376///immune system process+++GO:0002711///positive regulation of T cell mediated immunity+++GO:0006281///DNA repair+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019985///translesion synthesis+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0034644///cellular response to UV+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0045087///innate immune response+++GO:0045582///positive regulation of T cell differentiation+++GO:0048538///thymus development+++GO:0051260///protein homooligomerization+++GO:2000176///positive regulation of pro-T cell differentiation 268566 268566 'Gphn' mRNA 1633.03 1699.35 1420.42 16.7 17.34 14.49 6.13 7.71 7.11 16.17666667 6.983333333 690.01 807.51 775.36 1584.266667 757.6266667 1.74E-30 -1.071860098 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors+++04727///GABAergic synapse "GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse+++GO:0097060///synaptic membrane+++GO:0098690///glycinergic synapse+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse+++GO:0099091///postsynaptic specialization, intracellular component+++GO:0099144///anchored component of synaptic membrane+++GO:0099572///postsynaptic specialization+++GO:0099634///postsynaptic specialization membrane" GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0008940///nitrate reductase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0060090///molecular adaptor activity+++GO:0061598///molybdopterin adenylyltransferase activity+++GO:0061599///molybdopterin molybdotransferase activity+++GO:0098879///structural constituent of postsynaptic specialization GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0008152///metabolic process+++GO:0010038///response to metal ion+++GO:0018315///molybdenum incorporation into molybdenum-molybdopterin complex+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0045184///establishment of protein localization+++GO:0072579///glycine receptor clustering+++GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 268567 268567 'Tmem229b' mRNA 918 1007 954 13.29 14.43 14.67 13.23 10.83 12.24 14.13 12.1 1049 839 928 959.6666667 938.6666667 0.742730112 -0.045788775 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009617///response to bacterium 268591 268591 'Serpina5' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04610///Complement and coagulation cascades GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031091///platelet alpha granule+++GO:0031094///platelet dense tubular network+++GO:0032991///protein-containing complex+++GO:0036024///protein C inhibitor-TMPRSS7 complex+++GO:0036025///protein C inhibitor-TMPRSS11E complex+++GO:0036026///protein C inhibitor-PLAT complex+++GO:0036027///protein C inhibitor-PLAU complex+++GO:0036028///protein C inhibitor-thrombin complex+++GO:0036029///protein C inhibitor-KLK3 complex+++GO:0036030///protein C inhibitor-plasma kallikrein complex+++GO:0070062///extracellular exosome+++GO:0097181///protein C inhibitor-coagulation factor V complex+++GO:0097182///protein C inhibitor-coagulation factor Xa complex+++GO:0097183///protein C inhibitor-coagulation factor XI complex GO:0001972///retinoic acid binding+++GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity+++GO:0031210///phosphatidylcholine binding+++GO:0032190///acrosin binding GO:0007283///spermatogenesis+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0045861///negative regulation of proteolysis+++GO:0051346///negative regulation of hydrolase activity 268595 268595 'D430019H16Rik' mRNA 61 72 56 0.56 0.65 0.55 0.22 0.12 0.13 0.586666667 0.156666667 27 15 16 63 19.33333333 3.09E-05 -1.716618665 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 268656 268656 'Sptlc1' mRNA 1335 1371 1390 29.18 29.49 32.37 29.42 28.99 28.8 30.34666667 29.07 1549 1491 1464 1365.333333 1501.333333 0.176238534 0.123673177 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex+++GO:0035339///SPOTS complex "GO:0003824///catalytic activity+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding" GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0009058///biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:1904504///positive regulation of lipophagy+++GO:1904649///regulation of fat cell apoptotic process 268663 268663 'Cdhr2' mRNA 1 1 2 0.01 0.01 0.03 0.05 0.02 0 0.016666667 0.023333333 4 2 0 1.333333333 2 0.845963899 0.54772054 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection+++GO:0044214///spanning component of plasma membrane GO:0005509///calcium ion binding+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0030154///cell differentiation+++GO:0030855///epithelial cell differentiation+++GO:0032532///regulation of microvillus length+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0060243///negative regulation of cell growth involved in contact inhibition+++GO:0090675///intermicrovillar adhesion+++GO:0098609///cell-cell adhesion 268670 268670 'Zfp759' mRNA 184.5 173 186.99 2.71 2.51 3.02 1.24 1.93 2.14 2.746666667 1.77 97 152 157.14 181.4966667 135.38 0.085076541 -0.429221794 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 268697 268697 'Ccnb1' mRNA 61.61 56.75 55.19 1.49 1.35 1.42 12.9 12.84 12.84 1.42 12.86 612.39 595.33 589.97 57.85 599.23 2.30E-91 3.373223043 04068///FoxO signaling pathway+++04110///Cell cycle+++04114///Oocyte meiosis+++04115///p53 signaling pathway+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++05170///Human immunodeficiency virus 1 infection GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0097125///cyclin B1-CDK1 complex GO:0005113///patched binding+++GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle+++GO:0001556///oocyte maturation+++GO:0001701///in utero embryonic development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007080///mitotic metaphase plate congression+++GO:0007283///spermatogenesis+++GO:0009612///response to mechanical stimulus+++GO:0009636///response to toxic substance+++GO:0010629///negative regulation of gene expression+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0033129///positive regulation of histone phosphorylation+++GO:0042246///tissue regeneration+++GO:0042493///response to drug+++GO:0044772///mitotic cell cycle phase transition+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045787///positive regulation of cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046680///response to DDT+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048565///digestive tract development+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0051987///positive regulation of attachment of spindle microtubules to kinetochore+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060623///regulation of chromosome condensation+++GO:0065003///protein-containing complex assembly+++GO:0071283///cellular response to iron(III) ion+++GO:0071398///cellular response to fatty acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0071456///cellular response to hypoxia+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport+++GO:2000775///histone H3-S10 phosphorylation involved in chromosome condensation 268706 268706 'Slc38a9' mRNA 563 578 535 4.15 4.34 4.12 3.37 3.62 3.33 4.203333333 3.44 530 538 491 558.6666667 519.6666667 0.388807212 -0.115291033 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0071986///Ragulator complex+++GO:1905103///integral component of lysosomal membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0015190///L-leucine transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:0061459///L-arginine transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015711///organic anion transport+++GO:0015803///branched-chain amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0098655///cation transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1903400///L-arginine transmembrane transport 268709 268709 'Fam107a' mRNA 12797 13251 12141 234.54 238.84 235.85 138.94 132.63 138.59 236.41 136.72 8778 8199 8469 12729.66667 8482 7.88E-37 -0.597051624 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005515///protein binding GO:0001558///regulation of cell growth+++GO:0007049///cell cycle+++GO:0030041///actin filament polymerization+++GO:0030335///positive regulation of cell migration+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0031669///cellular response to nutrient levels+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0040008///regulation of growth+++GO:0050890///cognition+++GO:0051017///actin filament bundle assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:1900272///negative regulation of long-term synaptic potentiation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 268721 268721 'Zswim8' mRNA 949.71 865.13 888.48 12.1 10.3 12.11 10.1 8.72 9.66 11.50333333 9.493333333 931.11 796.97 885.35 901.1066667 871.1433333 0.626991186 -0.062288476 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031463///Cul3-RING ubiquitin ligase complex "GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1902667///regulation of axon guidance+++GO:2000627///positive regulation of miRNA catabolic process 268739 268739 'Arhgef40' mRNA 1795.2 1842.1 1811.38 14.89 15.1 16.13 15.22 14.12 13.89 15.37333333 14.41 2005.57 1832.55 1774.74 1816.226667 1870.953333 0.78153161 0.029312642 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 26874 26874 'Abcd2' mRNA 142.4 181.14 152.13 1.32 1.65 1.49 1.99 1.85 1.81 1.486666667 1.883333333 247.05 225.36 218 158.5566667 230.1366667 0.005528504 0.527432525 02010///ABC transporters+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0047617///acyl-CoA hydrolase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0007031///peroxisome organization+++GO:0009617///response to bacterium+++GO:0015910///peroxisomal long-chain fatty acid import+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0042760///very long-chain fatty acid catabolic process+++GO:0043217///myelin maintenance+++GO:0055085///transmembrane transport+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1990535///neuron projection maintenance+++GO:2001280///positive regulation of unsaturated fatty acid biosynthetic process 268741 268741 'Tox4' mRNA 1546.88 1545.77 1595.71 18.63 18.31 20.39 18.29 19.09 18.69 19.11 18.69 1748.01 1782.01 1730.19 1562.786667 1753.403333 0.076707377 0.153702603 "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0072357///PTW/PP1 phosphatase complex" GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding GO:0006357///regulation of transcription by RNA polymerase II 268747 268747 'Carmil3' mRNA 58 60 37 0.7 0.71 0.55 0.26 0.17 0.12 0.653333333 0.183333333 17 14 12 51.66666667 14.33333333 5.79E-05 -1.854188547 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 268749 268749 'Rnf31' mRNA 1218 1232 1173 19.32 19.23 19.74 14.46 13.58 13.52 19.43 13.85333333 1049 962 950 1207.666667 987 4.77E-04 -0.303291352 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0035631///CD40 receptor complex+++GO:0071797///LUBAC complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:1990450///linear polyubiquitin binding GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0023035///CD40 signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060546///negative regulation of necroptotic process+++GO:0097039///protein linear polyubiquitination 26875 26875 'Pclo' mRNA 402.27 375.92 341 1.18 1.1 1.07 0.11 0.14 0.14 1.116666667 0.13 43 56 52.92 373.0633333 50.64 4.83E-49 -2.896909854 04911///Insulin secretion GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0044316///cone cell pedicle+++GO:0044317///rod spherule+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0060077///inhibitory synapse+++GO:0097470///ribbon synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0001222///transcription corepressor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding+++GO:0098882///structural constituent of presynaptic active zone GO:0007010///cytoskeleton organization+++GO:0007416///synapse assembly+++GO:0016080///synaptic vesicle targeting+++GO:0017157///regulation of exocytosis+++GO:0019933///cAMP-mediated signaling+++GO:0030073///insulin secretion+++GO:0035418///protein localization to synapse+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0050808///synapse organization+++GO:0051036///regulation of endosome size+++GO:0097091///synaptic vesicle clustering+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0099526///presynapse to nucleus signaling pathway+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:1904071///presynaptic active zone assembly+++GO:1904666///regulation of ubiquitin protein ligase activity 268752 268752 'Wdfy2' mRNA 810.86 857.21 693.71 7.94 8.24 8.25 10.38 10.17 10.81 8.143333333 10.45333333 1235.8 1166.73 1214.43 787.26 1205.653333 1.18E-11 0.606444948 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0045600///positive regulation of fat cell differentiation 268756 268756 'Gulo' mRNA 3 10 3 0.07 0.24 0.08 0.2 0.2 0.16 0.13 0.186666667 9 9 7 5.333333333 8.333333333 0.594133513 0.647128033 00053///Ascorbate and aldarate metabolism+++01240///Biosynthesis of cofactors GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003885///D-arabinono-1,4-lactone oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016899///oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor+++GO:0050105///L-gulonolactone oxidase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0019853///L-ascorbic acid biosynthetic process 268759 268759 '9930012K11Rik' mRNA 72 88 79 2.07 2.49 2.41 4.55 4.68 3.9 2.323333333 4.376666667 182 183 151 79.66666667 172 1.53E-06 1.098760345 GO:0003674///molecular_function GO:0008150///biological_process 26877 26877 'B3galt1' mRNA 36 50 42 0.32 0.47 0.43 0.15 0.16 0.2 0.406666667 0.17 18 19 25 42.66666667 20.66666667 0.023401956 -1.055865593 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047275///glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006682///galactosylceramide biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0030259///lipid glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 26878 26878 'B3galt2' mRNA 157.8 180.64 190.54 1.85 2.08 2.37 0.68 0.6 0.64 2.1 0.64 66.62 57.44 60.97 176.3266667 61.67666667 7.54E-11 -1.541742589 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047275///glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006682///galactosylceramide biosynthetic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 268780 268780 'Egflam' mRNA 643.4 671.31 695.09 5.51 5.9 6.47 3.35 2.99 3.27 5.96 3.203333333 452.34 392.29 435.93 669.9333333 426.8533333 1.81E-08 -0.666059313 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0042995///cell projection+++GO:0043083///synaptic cleft+++GO:0045202///synapse+++GO:0048786///presynaptic active zone GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005539///glycosaminoglycan binding GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0030198///extracellular matrix organization 268783 268783 'Mtmr12' mRNA 805 822 808 9.44 9.52 10.05 9.41 9.7 9.82 9.67 9.643333333 922 927 935 811.6666667 928 0.073173655 0.181235437 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030017///sarcomere GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0019208///phosphatase regulator activity GO:0046856///phosphatidylinositol dephosphorylation+++GO:0050790///regulation of catalytic activity+++GO:1901998///toxin transport 26879 26879 'B3galnt1' mRNA 800.1 936 906 18.85 22.19 23.22 20.19 19.52 19.28 21.42 19.66333333 981 920.04 915 880.7 938.68 0.534932833 0.078497648 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047273///galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0009312///oligosaccharide biosynthetic process+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 268807 268807 'Klhl38' mRNA 30.06 32.99 32 0.39 0.43 0.54 0.33 0.66 0.66 0.453333333 0.55 26.19 47.94 40 31.68333333 38.04333333 0.64509722 0.257536485 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 268816 268816 'Mroh5' mRNA 0 0 2 0 0 0.05 0 0 0.02 0.016666667 0.006666667 0 0 1 0.666666667 0.333333333 0.863090843 -0.975320503 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 268822 268822 'Adck5' mRNA 499 565 513 13.93 15.54 15.2 9.74 9.45 8.88 14.89 9.356666667 401 380 354 525.6666667 378.3333333 1.17E-04 -0.486284896 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0008150///biological_process+++GO:0016310///phosphorylation 26885 26885 'Casp8ap2' mRNA 495 498 473 3.92 3.91 4.02 4.22 3.97 4.39 3.95 4.193333333 612 561 614 488.6666667 595.6666667 0.019844461 0.273853575 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016605///PML body GO:0002020///protease binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0032184///SUMO polymer binding+++GO:0042802///identical protein binding "GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0036337///Fas signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0097190///apoptotic signaling pathway" 268857 268857 'Nlrc3' mRNA 127.75 109.05 160.37 1.5 1.22 2.08 6.51 6.66 5.96 1.6 6.376666667 595.85 594.86 534.51 132.39 575.0733333 3.52E-37 2.103191328 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0031396///regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032496///response to lipopolysaccharide+++GO:0032687///negative regulation of interferon-alpha production+++GO:0032688///negative regulation of interferon-beta production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction+++GO:0042110///T cell activation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045824///negative regulation of innate immune response+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 268859 268859 'Rbfox1' mRNA 8 12 4 0.1 0.14 0.04 0.01 0.03 0.01 0.093333333 0.016666667 1 3 1 8 1.666666667 0.090001822 -2.251534053 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0010494///cytoplasmic stress granule+++GO:0097165///nuclear stress granule GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008022///protein C-terminus binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0050885///neuromuscular process controlling balance+++GO:2001014///regulation of skeletal muscle cell differentiation" 26886 26886 'Cenph' mRNA 7 10 4 0.37 0.46 0.23 3.13 2.96 2.9 0.353333333 2.996666667 72 69 64 7 68.33333333 1.66E-11 3.282181602 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus" GO:0005515///protein binding+++GO:0043515///kinetochore binding GO:0000278///mitotic cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007059///chromosome segregation+++GO:0051382///kinetochore assembly+++GO:0051383///kinetochore organization 268860 268860 'Abat' mRNA 1285 1269 1207 14.91 14.44 14.89 9.91 9.83 9.76 14.74666667 9.833333333 985 956 938 1253.666667 959.6666667 2.03E-06 -0.397011031 "00250///Alanine, aspartate and glutamate metabolism+++00280///Valine, leucine and isoleucine degradation+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++00650///Butanoate metabolism+++04727///GABAergic synapse" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0032144///4-aminobutyrate transaminase complex+++GO:0043005///neuron projection GO:0003824///catalytic activity+++GO:0003867///4-aminobutyrate transaminase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0032145///succinate-semialdehyde dehydrogenase binding+++GO:0034386///4-aminobutyrate:2-oxoglutarate transaminase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047298///(S)-3-amino-2-methylpropionate transaminase activity+++GO:0051536///iron-sulfur cluster binding GO:0001666///response to hypoxia+++GO:0007568///aging+++GO:0007620///copulation+++GO:0007626///locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0009448///gamma-aminobutyric acid metabolic process+++GO:0009449///gamma-aminobutyric acid biosynthetic process+++GO:0009450///gamma-aminobutyric acid catabolic process+++GO:0010039///response to iron ion+++GO:0014053///negative regulation of gamma-aminobutyric acid secretion+++GO:0021549///cerebellum development+++GO:0031652///positive regulation of heat generation+++GO:0032024///positive regulation of insulin secretion+++GO:0033602///negative regulation of dopamine secretion+++GO:0035094///response to nicotine+++GO:0035640///exploration behavior+++GO:0042135///neurotransmitter catabolic process+++GO:0042220///response to cocaine+++GO:0042493///response to drug+++GO:0045471///response to ethanol+++GO:0045776///negative regulation of blood pressure+++GO:0045964///positive regulation of dopamine metabolic process+++GO:0048148///behavioral response to cocaine+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0090331///negative regulation of platelet aggregation+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:1902722///positive regulation of prolactin secretion+++GO:1904450///positive regulation of aspartate secretion 26887 26887 'Chst4' mRNA 205 216 182 5.94 6.13 5.58 0.7 0.71 0.55 5.883333333 0.653333333 28 27 21 201 25.33333333 1.96E-29 -2.997679136 00533///Glycosaminoglycan biosynthesis - keratan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006477///protein sulfation+++GO:0006790///sulfur compound metabolic process+++GO:0006954///inflammatory response+++GO:0050901///leukocyte tethering or rolling+++GO:1903238///positive regulation of leukocyte tethering or rolling 268878 268878 'Atp13a5' mRNA 665 621 650 7.47 6.93 7.81 8.53 7.69 7.31 7.403333333 7.843333333 854 751 702 645.3333333 769 0.042878043 0.238767155 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006812///cation transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0098655///cation transmembrane transport 26888 26888 'Clec4a2' mRNA 73.46 112.43 91.45 3.96 5.8 4.97 28.92 28.95 28.91 4.91 28.92666667 637.82 672.75 660.68 92.44666667 657.0833333 4.38E-71 2.824651953 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding "GO:0001818///negative regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002470///plasmacytoid dendritic cell antigen processing and presentation+++GO:0006955///immune response+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0044419///interspecies interaction between organisms+++GO:0045087///innate immune response+++GO:0061760///antifungal innate immune response" 268880 268880 'Xxylt1' mRNA 257 214 190 4.95 4.04 3.92 4.84 3.63 4.78 4.303333333 4.416666667 288 211 275 220.3333333 258 0.30007037 0.21700776 00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0046872///metal ion binding" GO:0016266///O-glycan processing 268882 268882 'Fbxo45' mRNA 167 205 187 2.23 2.69 2.64 2.14 2.05 2.33 2.52 2.173333333 185 173 195 186.3333333 184.3333333 0.910420806 -0.027695113 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol+++GO:0099524///postsynaptic cytosol GO:0005515///protein binding GO:0001764///neuron migration+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0016567///protein ubiquitination+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021800///cerebral cortex tangential migration+++GO:0021957///corticospinal tract morphogenesis+++GO:0021960///anterior commissure morphogenesis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0060384///innervation+++GO:0060386///synapse assembly involved in innervation 268885 268885 'Stfa2l1' mRNA 6 2 4 1.42 0.48 1 1.04 1.08 1.09 0.966666667 1.07 5 5 5 4 5 0.854885182 0.307277477 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 26889 26889 'Cln8' mRNA 949 960.81 831 17.91 17.47 16.28 25.87 22.89 24.43 17.22 24.39666667 1654.15 1424 1465.01 913.6033333 1514.386667 2.12E-17 0.718710718 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0098793///presynapse GO:0005515///protein binding+++GO:0097001///ceramide binding GO:0001306///age-dependent response to oxidative stress+++GO:0006644///phospholipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0007006///mitochondrial membrane organization+++GO:0007040///lysosome organization+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0007628///adult walking behavior+++GO:0008203///cholesterol metabolic process+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0008361///regulation of cell size+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021523///somatic motor neuron differentiation+++GO:0035176///social behavior+++GO:0043066///negative regulation of apoptotic process+++GO:0044257///cellular protein catabolic process+++GO:0044265///cellular macromolecule catabolic process+++GO:0044267///cellular protein metabolic process+++GO:0045494///photoreceptor cell maintenance+++GO:0050881///musculoskeletal movement+++GO:0050884///neuromuscular process controlling posture+++GO:0050885///neuromuscular process controlling balance+++GO:0051348///negative regulation of transferase activity+++GO:0051935///glutamate reuptake+++GO:0055088///lipid homeostasis+++GO:0060041///retina development in camera-type eye+++GO:0060052///neurofilament cytoskeleton organization 268890 268890 'Lsamp' mRNA 808 867 732 4.74 5 4.56 0.34 0.39 0.37 4.766666667 0.366666667 66 75 70 802.3333333 70.33333333 2.09E-121 -3.52075996 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane GO:0007155///cell adhesion+++GO:0035641///locomotory exploration behavior 268902 268902 'Robo2' mRNA 64.99 101 54.21 0.33 0.54 0.29 0.24 0.21 0.18 0.386666667 0.21 53.94 45.89 38 73.4 45.94333333 0.063661175 -0.691287225 04360///Axon guidance+++04361///Axon regeneration GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030673///axolemma GO:0008046///axon guidance receptor activity+++GO:0042802///identical protein binding GO:0001656///metanephros development+++GO:0001657///ureteric bud development+++GO:0003148///outflow tract septum morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003272///endocardial cushion formation+++GO:0006935///chemotaxis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0016199///axon midline choice point recognition+++GO:0021510///spinal cord development+++GO:0021891///olfactory bulb interneuron development+++GO:0030154///cell differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0032870///cellular response to hormone stimulus+++GO:0035385///Roundabout signaling pathway+++GO:0035481///positive regulation of Notch signaling pathway involved in heart induction+++GO:0035904///aorta development+++GO:0050772///positive regulation of axonogenesis+++GO:0050925///negative regulation of negative chemotaxis+++GO:0060412///ventricular septum morphogenesis+++GO:0061364///apoptotic process involved in luteolysis 268903 268903 'Nrip1' mRNA 1093 1062 911 3.97 3.79 3.24 3.88 3.15 4.14 3.666666667 3.723333333 1269 1025 1295 1022 1196.333333 0.045800614 0.216979591 GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0030331///estrogen receptor binding+++GO:0035257///nuclear hormone receptor binding+++GO:0035259///glucocorticoid receptor binding+++GO:0042826///histone deacetylase binding+++GO:0042974///retinoic acid receptor binding+++GO:0046965///retinoid X receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001543///ovarian follicle rupture+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0019915///lipid storage+++GO:0030728///ovulation+++GO:0032922///circadian regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0071392///cellular response to estradiol stimulus 26891 26891 'Cops4' mRNA 1911 1929 2027 61.97 61.72 70.38 61.16 63.05 62.55 64.69 62.25333333 2137 2157 2136.14 1955.666667 2143.38 0.177973557 0.118547276 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0008180///COP9 signalosome+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0005515///protein binding GO:0000338///protein deneddylation 26893 26893 'Cops6' mRNA 2736 2824 2557 156.59 159.72 155.27 190.19 200.29 186.01 157.1933333 192.1633333 3812 3914 3604 2705.666667 3776.666667 1.14E-13 0.470854689 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome GO:0005515///protein binding+++GO:0008237///metallopeptidase activity+++GO:0070122///isopeptidase activity GO:0000338///protein deneddylation 268930 268930 'Pkmyt1' mRNA 180.61 165.91 173.05 5.04 4.52 5.17 8.58 10.52 8.04 4.91 9.046666667 343.38 421.49 315.8 173.19 360.2233333 1.31E-09 1.047747554 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding" "GO:0001678///cellular glucose homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0009791///post-embryonic development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010923///negative regulation of phosphatase activity+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0032350///regulation of hormone metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051321///meiotic cell cycle+++GO:0060539///diaphragm development+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus" 268932 268932 'Caskin1' mRNA 726 752 553 7.12 7.22 5.96 2.76 2.85 2.97 6.766666667 2.86 312 315 329 677 318.6666667 9.27E-18 -1.092868945 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding GO:0007165///signal transduction 268933 268933 'Wdr24' mRNA 734 709 640 12.98 12.34 12.01 10.17 8.78 9.6 12.44333333 9.516666667 662 558 605 694.3333333 608.3333333 0.081206771 -0.202010457 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0061700///GATOR2 complex GO:0003674///molecular_function GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation 268934 268934 'Grm4' mRNA 16 30 24 0.3 0.42 0.43 0.06 0.2 0.12 0.383333333 0.126666667 4 12 8 23.33333333 8 0.028656957 -1.5495371 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043198///dendritic shaft+++GO:0048787///presynaptic active zone membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0001642///group III metabotropic glutamate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005516///calmodulin binding+++GO:0008066///glutamate receptor activity+++GO:0048306///calcium-dependent protein binding "GO:0000187///activation of MAPK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007612///learning+++GO:0043410///positive regulation of MAPK cascade+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:2000300///regulation of synaptic vesicle exocytosis" 268935 268935 'Scube3' mRNA 235 255 145 1.98 2.02 1.27 0.65 0.67 0.64 1.756666667 0.653333333 89 83 90 211.6666667 87.33333333 4.32E-08 -1.27873746 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface GO:0005509///calcium ion binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0045880///positive regulation of smoothened signaling pathway 268936 268936 'Brpf3' mRNA 155 172 174 1.5 1.96 1.98 2.28 1.76 1.94 1.813333333 1.993333333 229 169 192 167 196.6666667 0.332749564 0.220117806 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0006325///chromatin organization+++GO:0043966///histone H3 acetylation+++GO:0043972///histone H3-K23 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045740///positive regulation of DNA replication 26894 26894 'Cops7a' mRNA 2640.14 2469.08 2495.64 88.33 82.05 89.66 84.66 80.14 80.38 86.68 81.72666667 2886.11 2687.4 2677.14 2534.953333 2750.216667 0.173061622 0.104797405 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008180///COP9 signalosome GO:0003674///molecular_function GO:0000338///protein deneddylation+++GO:0010387///COP9 signalosome assembly 268949 268949 'Mucl3' mRNA 3 1 0 0.06 0.02 0 0.02 0.04 0.04 0.026666667 0.033333333 1 2 2 1.333333333 1.666666667 0.894577642 0.340314837 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 26895 26895 'Cops7b' mRNA 781 848 702 18.08 19.08 17.96 13.27 14.47 12.51 18.37333333 13.41666667 639.04 679 563 777 627.0133333 0.005851123 -0.318057929 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome GO:0003674///molecular_function GO:0000338///protein deneddylation+++GO:0010387///COP9 signalosome assembly 268958 268958 'Capn11' mRNA 12 8 4 0.28 0.24 0.13 0.11 0.04 0.06 0.216666667 0.07 4 2 3 8 3 0.244590207 -1.41655733 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 26896 26896 'Med14' mRNA 779 735 392 6.45 5.86 3.38 4.3 4.19 4.9 5.23 4.463333333 617 579 678 635.3333333 624.6666667 0.922484347 -0.02296089 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 26897 26897 'Acot1' mRNA 534.3 597.91 624.79 20.14 22.22 24.98 20.27 18.47 17.37 22.44666667 18.70333333 617.88 549.3 512.2 585.6666667 559.7933333 0.618707035 -0.080341783 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++04913///Ovarian steroidogenesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process 268970 268970 'Arhgap28' mRNA 505.1 582.98 493.89 5.27 5.68 5.28 5.53 5.02 4.84 5.41 5.13 636.04 574 551.86 527.3233333 587.3 0.272957789 0.145610173 GO:0005737///cytoplasm GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0030833///regulation of actin filament polymerization+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0051497///negative regulation of stress fiber assembly+++GO:1904425///negative regulation of GTP binding 268973 268973 'Nlrc4' mRNA 8 11 12 0.11 0.15 0.18 1.04 1.13 0.62 0.146666667 0.93 86 90 50 10.33333333 75.33333333 3.76E-10 2.851314062 04621///NOD-like receptor signaling pathway+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0061702///inflammasome complex+++GO:0072557///IPAF inflammasome complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0061133///endopeptidase activator activity+++GO:0089720///caspase binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0010954///positive regulation of protein processing+++GO:0016045///detection of bacterium+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0042742///defense response to bacterium+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization+++GO:0070269///pyroptosis+++GO:0097202///activation of cysteine-type endopeptidase activity 268977 268977 'Ltbp1' mRNA 5168 5411 5330 49.58 50.95 54.09 17.32 14.67 16.44 51.54 16.14333333 2091 1732 1937 5303 1920 1.66E-96 -1.479984855 04350///TGF-beta signaling pathway GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0038045///large latent transforming growth factor-beta complex+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0019838///growth factor binding+++GO:0050431///transforming growth factor beta binding+++GO:0050436///microfibril binding GO:0003281///ventricular septum development+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035583///sequestering of TGFbeta in extracellular matrix+++GO:0035904///aorta development+++GO:0060976///coronary vasculature development+++GO:1901388///regulation of transforming growth factor beta activation 268980 268980 'Strn' mRNA 717 655 802 4.8 4.25 5.68 5.73 5.07 5.27 4.91 5.356666667 994 854 888 724.6666667 912 0.010879262 0.313884917 04013///MAPK signaling pathway - fly GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0090443///FAR/SIN/STRIPAK complex GO:0005516///calmodulin binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0044877///protein-containing complex binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070016///armadillo repeat domain binding GO:0007626///locomotory behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0016358///dendrite development 268996 268996 'Ss18' mRNA 2121 2074 2113 38.18 37.02 40.7 35.43 34.71 31.98 38.63333333 34.04 2240 2142 1959 2102.666667 2113.666667 0.958468389 -0.00583978 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0015630///microtubule cytoskeleton+++GO:0016514///SWI/SNF complex+++GO:0071564///npBAF complex GO:0003713///transcription coactivator activity+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0000226///microtubule cytoskeleton organization+++GO:0000902///cell morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0009410///response to xenobiotic stimulus+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048013///ephrin receptor signaling pathway+++GO:0097150///neuronal stem cell population maintenance" 26900 26900 'Ddx3y' mRNA 1114 1265 1168 12.86 14.31 14.28 14.03 12.63 13.02 13.81666667 13.22666667 1403 1232 1260 1182.333333 1298.333333 0.223706441 0.122212895 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043186///P granule GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0007276///gamete generation+++GO:0030154///cell differentiation 269003 269003 'Sap130' mRNA 1067.7 1009.49 983.98 11.18 10.25 11.24 9.25 8.25 10.13 10.89 9.21 987.69 869.56 1038.77 1020.39 965.34 0.425281926 -0.092116706 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0070822///Sin3-type complex GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated" 26901 26901 'Ss18l2' mRNA 1086 1094 1097 174.3 175.47 186.94 162.64 177.19 165.5 178.9033333 168.4433333 1153 1219 1129 1092.333333 1167 0.44080322 0.083295768 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003713///transcription coactivator activity "GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050775///positive regulation of dendrite morphogenesis" 269016 269016 'Sh3rf2' mRNA 115 132 94 1.74 1.84 1.58 2.22 1.38 1.98 1.72 1.86 160 111 154 113.6666667 141.6666667 0.249371746 0.308703971 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0008157///protein phosphatase 1 binding+++GO:0016740///transferase activity+++GO:0019902///phosphatase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010923///negative regulation of phosphatase activity+++GO:0016567///protein ubiquitination+++GO:0030335///positive regulation of cell migration+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0046328///regulation of JNK cascade+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0051865///protein autoubiquitination 269019 269019 'Stk32a' mRNA 50 62 38 0.72 0.88 0.58 0.3 0.26 0.28 0.726666667 0.28 24 20 22 50 22 0.006008792 -1.189425703 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 269023 269023 'Zfp608' mRNA 491 461 476 4.28 3.95 4.41 2.78 2.08 2.93 4.213333333 2.596666667 367 269 374 476 336.6666667 6.32E-04 -0.514295641 GO:0005634///nucleus GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0033085///negative regulation of T cell differentiation in thymus 26903 26903 'Dysf' mRNA 187 193 177 1.47 1.48 1.45 0.99 1.29 1.19 1.466666667 1.156666667 149 187 174 185.6666667 170 0.575937352 -0.13607779 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030139///endocytic vesicle+++GO:0030315///T-tubule+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034451///centriolar satellite+++GO:0042383///sarcolemma+++GO:0098857///membrane microdomain GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001778///plasma membrane repair+++GO:0001816///cytokine production+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002280///monocyte activation involved in immune response+++GO:0002281///macrophage activation involved in immune response+++GO:0006071///glycerol metabolic process+++GO:0006906///vesicle fusion+++GO:0007009///plasma membrane organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007519///skeletal muscle tissue development+++GO:0010629///negative regulation of gene expression+++GO:0014902///myotube differentiation+++GO:0019915///lipid storage+++GO:0032091///negative regulation of protein binding+++GO:0033292///T-tubule organization+++GO:0042177///negative regulation of protein catabolic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045444///fat cell differentiation+++GO:0045785///positive regulation of cell adhesion+++GO:0048747///muscle fiber development+++GO:0050765///negative regulation of phagocytosis+++GO:0055001///muscle cell development+++GO:0061025///membrane fusion+++GO:0071470///cellular response to osmotic stress+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090279///regulation of calcium ion import+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:1902915///negative regulation of protein polyubiquitination+++GO:1904428///negative regulation of tubulin deacetylation 269033 269033 '4930503L19Rik' mRNA 147 183 172 3.29 3.74 3.85 6.77 6.56 7.8 3.626666667 7.043333333 379 352 407 167.3333333 379.3333333 4.00E-13 1.168087442 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016604///nuclear body+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004819///glutamine-tRNA ligase activity+++GO:0004823///leucine-tRNA ligase activity+++GO:0005096///GTPase activator activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006425///glutaminyl-tRNA aminoacylation+++GO:0006429///leucyl-tRNA aminoacylation+++GO:0008285///negative regulation of cell proliferation+++GO:0008361///regulation of cell size+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0043547///positive regulation of GTPase activity+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity+++GO:1904263///positive regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 269037 269037 'Ctif' mRNA 275 264 210 2.37 2.24 1.92 1.63 1.31 1.17 2.176666667 1.37 218 171 151 249.6666667 180 0.01467117 -0.481695075 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0008494///translation activator activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation" 26904 26904 'Sh2d1b1' mRNA 15 11 9 0.33 0.24 0.21 0.8 0.66 1.37 0.26 0.943333333 42 34 70 11.66666667 48.66666667 6.73E-05 2.053398293 04650///Natural killer cell mediated cytotoxicity GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0035591///signaling adaptor activity GO:0002250///adaptive immune response+++GO:0002366///leukocyte activation involved in immune response+++GO:0002376///immune system process+++GO:0002717///positive regulation of natural killer cell mediated immunity+++GO:0002769///natural killer cell inhibitory signaling pathway+++GO:0009967///positive regulation of signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation 26905 26905 'Eif2s3x' mRNA 1940 1919 1933 29.37 28.58 31.04 30.03 27.7 28.85 29.66333333 28.86 2283 2057 2124 1930.666667 2154.666667 0.067034463 0.14490733 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005850///eukaryotic translation initiation factor 2 complex "GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008135///translation factor activity, RNA binding+++GO:0016787///hydrolase activity" GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0045903///positive regulation of translational fidelity 269053 269053 'Gpr152' mRNA 590 619 640 8.12 8.38 9.35 0.57 0.56 0.68 8.616666667 0.603333333 48 46 55 616.3333333 49.66666667 2.23E-94 -3.647269961 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 269060 269060 'Dagla' mRNA 729 745 564 6.86 6.9 5.64 2.25 2.35 2.59 6.466666667 2.396666667 275 282 307 679.3333333 288 3.29E-22 -1.244130551 04723///Retrograde endocannabinoid signaling+++04745///Phototransduction - fly+++04925///Aldosterone synthesis and secretion GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031901///early endosome membrane+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043196///varicosity+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0099055///integral component of postsynaptic membrane GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0007405///neuroblast proliferation+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0022008///neurogenesis+++GO:0042136///neurotransmitter biosynthetic process+++GO:0046340///diacylglycerol catabolic process+++GO:0071926///endocannabinoid signaling pathway+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0150077///regulation of neuroinflammatory response 269061 269061 'Cpsf7' mRNA 1270 1254 971 19.25 18.62 15.53 13.96 13.17 13.85 17.8 13.66 1066 982 1017 1165 1021.666667 0.058066722 -0.196742272 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005849///mRNA cleavage factor complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006397///mRNA processing+++GO:0051262///protein tetramerization+++GO:0051290///protein heterotetramerization+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:0110104///mRNA alternative polyadenylation+++GO:1990120///messenger ribonucleoprotein complex assembly 26908 26908 'Eif2s3y' mRNA 1163.83 1306.7 1208.21 28.23 32.36 30.9 27.43 26.24 26.24 30.49666667 26.63666667 1269.61 1144.18 1126.62 1226.246667 1180.136667 0.53847688 -0.067772911 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005850///eukaryotic translation initiation factor 2 complex "GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008135///translation factor activity, RNA binding+++GO:0016787///hydrolase activity" GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0045903///positive regulation of translational fidelity 26909 26909 'Exo1' mRNA 5 0 6 0.1 0 0.12 1.13 1.85 1.42 0.073333333 1.466666667 78 118 89 3.666666667 95 1.91E-16 4.681006877 03430///Mismatch repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016604///nuclear body "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017108///5'-flap endonuclease activity+++GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0048256///flap endonuclease activity+++GO:0051908///double-stranded DNA 5'-3' exodeoxyribonuclease activity" GO:0002376///immune system process+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0045190///isotype switching+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 269109 269109 'Dpp10' mRNA 205 189 195 2.36 2.13 2.39 0.11 0.09 0.08 2.293333333 0.093333333 11 9 8 196.3333333 9.333333333 6.15E-36 -4.408102561 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding GO:0006508///proteolysis+++GO:0072659///protein localization to plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1903078///positive regulation of protein localization to plasma membrane 269113 269113 'Nup54' mRNA 372 424 334 8.94 9.97 8.53 9.45 9.81 11.04 9.146666667 10.1 450 457 511 376.6666667 472.6666667 0.022087179 0.319635471 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0044613///nuclear pore central transport channel GO:0017056///structural constituent of nuclear pore+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006605///protein targeting+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006999///nuclear pore organization+++GO:0015031///protein transport+++GO:0036228///protein localization to nuclear inner membrane+++GO:0042306///regulation of protein import into nucleus+++GO:0051028///mRNA transport 269116 269116 'Nfasc' mRNA 2386.92 2318 2167 12.83 12.36 11.95 7.06 6.85 6.38 12.38 6.763333333 1573 1453 1392.36 2290.64 1472.786667 1.37E-19 -0.648616871 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005918///septate junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0033010///paranodal junction+++GO:0033268///node of Ranvier+++GO:0033270///paranode region of axon+++GO:0043194///axon initial segment+++GO:0043209///myelin sheath+++GO:0097454///Schwann cell microvillus GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion+++GO:0098632///cell-cell adhesion mediator activity GO:0002175///protein localization to paranode region of axon+++GO:0007155///cell adhesion+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007422///peripheral nervous system development+++GO:0019226///transmission of nerve impulse+++GO:0030913///paranodal junction assembly+++GO:0034113///heterotypic cell-cell adhesion+++GO:0042552///myelination+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0050808///synapse organization+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0072659///protein localization to plasma membrane+++GO:0098609///cell-cell adhesion 26912 26912 'Gcat' mRNA 1219 1188 1174 28.75 27.59 29.46 16.08 18.62 16.31 28.6 17.00333333 784 883 770 1193.666667 812.3333333 4.29E-09 -0.566355898 "00260///Glycine, serine and threonine metabolism" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016607///nuclear speck "GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0008890///glycine C-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0030170///pyridoxal phosphate binding" GO:0006567///threonine catabolic process+++GO:0008150///biological_process+++GO:0009058///biosynthetic process+++GO:0019518///L-threonine catabolic process to glycine 269120 269120 'Optc' mRNA 2 3 8 0.11 0.11 0.41 0.33 0.24 0.24 0.21 0.27 8 5 5 4.333333333 6 0.772074606 0.429119751 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0016525///negative regulation of angiogenesis+++GO:0030199///collagen fibril organization 26913 26913 'Gprin1' mRNA 4 7 0 0.05 0.09 0 0 0 0.01 0.046666667 0.003333333 0 0 1 3.666666667 0.333333333 0.172193573 -3.329021481 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0051219///phosphoprotein binding GO:0031175///neuron projection development 269132 269132 'Colgalt2' mRNA 2335 2470 2267 31.05 32.31 31.98 17.86 17.09 17.07 31.78 17.34 1546 1445 1431 2357.333333 1474 1.58E-23 -0.688995881 00310///Lysine degradation+++00514///Other types of O-glycan biosynthesis GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0050211///procollagen galactosyltransferase activity" 26914 26914 'Macroh2a1' mRNA 969 917 935 21.9 20.08 21.54 28.09 23.92 28.14 21.17333333 26.71666667 1323 1129 1301 940.3333333 1251 2.29E-05 0.398309656 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000793///condensed chromosome+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005730///nucleolus+++GO:0005813///centrosome GO:0000182///rDNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0019899///enzyme binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0007549///dosage compensation+++GO:0019216///regulation of lipid metabolic process+++GO:0031507///heterochromatin assembly+++GO:0033128///negative regulation of histone phosphorylation+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0040029///regulation of gene expression, epigenetic+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0071169///establishment of protein localization to chromatin+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902750///negative regulation of cell cycle G2/M phase transition+++GO:1902882///regulation of response to oxidative stress+++GO:1902883///negative regulation of response to oxidative stress+++GO:1902884///positive regulation of response to oxidative stress+++GO:1903226///positive regulation of endodermal cell differentiation+++GO:1904815///negative regulation of protein localization to chromosome, telomeric region" 269152 269152 'Kif26b' mRNA 94 107 70.03 0.42 0.5 0.32 0.17 0.14 0.11 0.413333333 0.14 34.63 27 23 90.34333333 28.21 7.33E-07 -1.696176109 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0007275///multicellular organism development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030010///establishment of cell polarity+++GO:0072092///ureteric bud invasion 26918 26918 'Ern2' mRNA 2 2 1 0.05 0.05 0.03 0 0 0 0.043333333 0 0 0 0 1.666666667 0 0.330935189 -3.178038812 GO:0005637///nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:1990597///AIP1-IRE1 complex+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:1990630///IRE1-RACK1-PP2A complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030544///Hsp70 protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051879///Hsp90 protein binding "GO:0001935///endothelial cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006379///mRNA cleavage+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0007050///cell cycle arrest+++GO:0007257///activation of JUN kinase activity+++GO:0008152///metabolic process+++GO:0016075///rRNA catabolic process+++GO:0016310///phosphorylation+++GO:0030263///apoptotic chromosome condensation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0033120///positive regulation of RNA splicing+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0051726///regulation of cell cycle+++GO:0070054///mRNA splicing, via endonucleolytic cleavage and ligation+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071333///cellular response to glucose stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0098787///mRNA cleavage involved in mRNA processing+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1901142///insulin metabolic process+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1990579///peptidyl-serine trans-autophosphorylation" 269180 269180 'Inpp4a' mRNA 1116 1005 1058 10.33 9.1 10.43 7.39 7.1 7.04 9.953333333 7.176666667 914 848 855 1059.666667 872.3333333 0.002604744 -0.293998803 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031901///early endosome membrane+++GO:0031965///nuclear membrane+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane "GO:0016316///phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0017161///inositol-1,3,4-trisphosphate 4-phosphatase activity+++GO:0034597///phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity+++GO:0052828///inositol-3,4-bisphosphate 4-phosphatase activity" GO:0006798///polyphosphate catabolic process+++GO:0016311///dephosphorylation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process 269181 269181 'Mgat4a' mRNA 284 259 240 2.07 1.86 1.85 3.68 3.39 3.37 1.926666667 3.48 581 523 516 261 540 8.64E-16 1.037851754 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008454///alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation 26919 26919 'Zfp346' mRNA 618 643 684 9.34 9.75 11.08 8 6.99 7.27 10.05666667 7.42 600 513 525 648.3333333 546 0.036501596 -0.263387294 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding GO:0043065///positive regulation of apoptotic process 269198 269198 'Nbeal1' mRNA 1522 1497 1350 5.17 4.9 4.87 3.26 2.61 3.1 4.98 2.99 1088 874 1011 1456.333333 991 2.63E-10 -0.567049084 GO:0005829///cytosol+++GO:0016020///membrane GO:0019901///protein kinase binding GO:0008104///protein localization 26920 26920 'Cntrl' mRNA 623 589 572 4.64 4.06 4.4 4.72 4.76 4.69 4.366666667 4.723333333 723 694 701 594.6666667 706 0.031044813 0.236037873 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0072687///meiotic spindle+++GO:0090543///Flemming body+++GO:0090619///meiotic spindle pole+++GO:0097431///mitotic spindle pole+++GO:0120103///centriolar subdistal appendage GO:0003674///molecular_function+++GO:0008092///cytoskeletal protein binding GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0003281///ventricular septum development+++GO:0007049///cell cycle+++GO:0035904///aorta development+++GO:0048132///female germ-line stem cell asymmetric division+++GO:0051301///cell division+++GO:0051493///regulation of cytoskeleton organization+++GO:0060976///coronary vasculature development 269209 269209 'Stk36' mRNA 775 780 766 7.86 7.78 8.24 2.1 2.6 1.92 7.96 2.206666667 239 288 211 773.6666667 246 2.08E-36 -1.664169939 04341///Hedgehog signaling pathway - fly GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0003351///epithelial cilium movement+++GO:0006468///protein phosphorylation+++GO:0007224///smoothened signaling pathway+++GO:0007228///positive regulation of hh target transcription factor activity+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0009791///post-embryonic development+++GO:0016310///phosphorylation+++GO:0030030///cell projection organization+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0060271///cilium assembly 26921 26921 'Map4k4' mRNA 748 670 636 6.59 5.85 5.99 5.92 5.01 5.63 6.143333333 5.52 758 624 699 684.6666667 693.6666667 0.965918071 0.006947081 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0005925///focal adhesion GO:0000166///nucleotide binding+++GO:0004111///creatine kinase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0010977///negative regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032014///positive regulation of ARF protein signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0046328///regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0048812///neuron projection morphogenesis+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070571///negative regulation of neuron projection regeneration+++GO:0120183///positive regulation of focal adhesion disassembly 26922 26922 'Mecr' mRNA 888 932 922 37.83 39 41.41 34.32 33.34 34.78 39.41333333 34.14666667 915 860 889 914 888 0.656946667 -0.054614735 00061///Fatty acid biosynthesis+++00062///Fatty acid elongation+++01212///Fatty acid metabolism GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0005102///signaling receptor binding+++GO:0016491///oxidoreductase activity+++GO:0016922///nuclear receptor binding+++GO:0019166///trans-2-enoyl-CoA reductase (NADPH) activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process 269224 269224 'Pask' mRNA 156 151 165 1.63 1.55 1.83 1.32 1.16 1.35 1.67 1.276666667 146 123 143 157.3333333 137.3333333 0.387570608 -0.211168076 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035091///phosphatidylinositol binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0046777///protein autophosphorylation+++GO:0070092///regulation of glucagon secretion+++GO:0097009///energy homeostasis 269233 269233 'Fam171a1' mRNA 402 458 420 5.46 6.18 6.14 8.43 9.18 8.96 5.926666667 8.856666667 712 756 726 426.6666667 731.3333333 9.81E-12 0.766578769 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008360///regulation of cell shape+++GO:0043149///stress fiber assembly 269252 269252 'Gtf3c4' mRNA 810 782 447 6.09 5.77 3.59 2.09 2.09 2.42 5.15 2.2 319 313 359 679.6666667 330.3333333 1.03E-09 -1.040524802 GO:0000127///transcription factor TFIIIC complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0004402///histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0008150///biological_process+++GO:0016573///histone acetylation 269254 269254 'Setx' mRNA 708 794 701 3.37 3.72 3.54 3.34 3.03 3.25 3.543333333 3.206666667 808 716 760 734.3333333 761.3333333 0.767803997 0.040612999 05014///Amyotrophic lateral sclerosis "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0045171///intercellular bridge" GO:0000166///nucleotide binding+++GO:0001147///transcription termination site sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0000165///MAPK cascade+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006353///DNA-templated transcription, termination+++GO:0006369///termination of RNA polymerase II transcription+++GO:0006376///mRNA splice site selection+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0007623///circadian rhythm+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010976///positive regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0033120///positive regulation of RNA splicing+++GO:0034599///cellular response to oxidative stress+++GO:0043066///negative regulation of apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0060566///positive regulation of DNA-templated transcription, termination+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071300///cellular response to retinoic acid+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:2000806///positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled" 26926 26926 'Aifm1' mRNA 1036 1061 1015 26.07 26.29 27.09 23.13 25.61 24.61 26.48333333 24.45 1057 1143 1089 1037.333333 1096.333333 0.538214631 0.0689022 04210///Apoptosis+++04214///Apoptosis - fly+++04217///Necroptosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0003677///DNA binding+++GO:0003954///NADH dehydrogenase activity+++GO:0004174///electron-transferring-flavoprotein dehydrogenase activity+++GO:0005515///protein binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0046983///protein dimerization activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0002931///response to ischemia+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006979///response to oxidative stress+++GO:0008637///apoptotic mitochondrial changes+++GO:0009636///response to toxic substance+++GO:0010942///positive regulation of cell death+++GO:0012501///programmed cell death+++GO:0022904///respiratory electron transport chain+++GO:0030182///neuron differentiation+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045041///protein import into mitochondrial intermembrane space+++GO:0051402///neuron apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071392///cellular response to estradiol stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:1902065///response to L-glutamate+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:1904045///cellular response to aldosterone 269261 269261 'Rpl12' mRNA 933.98 899.87 959.25 108.76 104.22 118.56 188.22 200.86 195.05 110.5133333 194.71 1845.46 1915 1843.85 931.0333333 1868.103333 9.25E-32 0.992349272 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0070180///large ribosomal subunit rRNA binding GO:0006412///translation 26927 26927 'Foxl2' mRNA 10 4 8 0.22 0.09 0.19 0.12 0.06 0.18 0.166666667 0.12 6 3 9 7.333333333 6 0.820389325 -0.309197081 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090543///Flemming body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0043028///cysteine-type endopeptidase regulator activity involved in apoptotic process+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0001555///oocyte growth+++GO:0002074///extraocular skeletal muscle development+++GO:0006309///apoptotic DNA fragmentation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007338///single fertilization+++GO:0008585///female gonad development+++GO:0009653///anatomical structure morphogenesis+++GO:0019101///female somatic sex determination+++GO:0030154///cell differentiation+++GO:0033686///positive regulation of luteinizing hormone secretion+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048048///embryonic eye morphogenesis+++GO:0060014///granulosa cell differentiation+++GO:0060065///uterus development" 269275 269275 'Acvr1c' mRNA 1 4 4 0.01 0.02 0.02 0.01 0.01 0 0.016666667 0.006666667 1 2 0 3 1 0.463886189 -1.601720559 04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0048179///activin receptor complex "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016361///activin receptor activity, type I+++GO:0016740///transferase activity+++GO:0019838///growth factor binding+++GO:0038100///nodal binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0048185///activin binding+++GO:0070700///BMP receptor binding" GO:0001701///in utero embryonic development+++GO:0001834///trophectodermal cell proliferation+++GO:0002021///response to dietary excess+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0007181///transforming growth factor beta receptor complex assembly+++GO:0007368///determination of left/right symmetry+++GO:0007399///nervous system development+++GO:0009749///response to glucose+++GO:0016310///phosphorylation+++GO:0019915///lipid storage+++GO:0030154///cell differentiation+++GO:0030262///apoptotic nuclear changes+++GO:0032868///response to insulin+++GO:0032924///activin receptor signaling pathway+++GO:0038092///nodal signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0046676///negative regulation of insulin secretion+++GO:0071363///cellular response to growth factor stimulus+++GO:1901164///negative regulation of trophoblast cell migration+++GO:1901383///negative regulation of chorionic trophoblast cell proliferation 269295 269295 'Rtn4rl2' mRNA 923 872 109 28.28 26.22 3.45 0.68 0.69 1.11 19.31666667 0.826666667 27 26 43 634.6666667 32 1.05E-06 -4.287658828 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0038023///signaling receptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:0022038///corpus callosum development+++GO:0031103///axon regeneration 26931 26931 'Ppp2r5c' mRNA 1571 1620 1574 25.71 26.24 28.04 34.16 31.86 32.6 26.66333333 32.87333333 2293 2077 2049 1588.333333 2139.666667 2.21E-08 0.416880135 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection "GO:0000159///protein phosphatase type 2A complex+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol" GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0072542///protein phosphatase activator activity "GO:0006470///protein dephosphorylation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0031952///regulation of protein autophosphorylation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity" 26932 26932 'Ppp2r5e' mRNA 819 847 426 6.89 6.98 3.78 3.54 4.56 4.28 5.883333333 4.126666667 489 611 569 697.3333333 556.3333333 0.375614744 -0.320484574 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019888///protein phosphatase regulator activity+++GO:0072542///protein phosphatase activator activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0031952///regulation of protein autophosphorylation+++GO:0050790///regulation of catalytic activity 269328 269328 'Muc15' mRNA 2659 2744 2568 44.36 45.03 45.46 21.06 21.1 20.13 44.95 20.76333333 1453 1423 1345 2657 1407 3.92E-42 -0.92867209 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 269336 269336 'Ccdc32' mRNA 578 547 568 21.16 19.96 21.52 16.68 17.46 18.19 20.88 17.44333333 521 533 548 564.3333333 534 0.517607907 -0.09211623 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0044782///cilium organization+++GO:0060322///head development 269338 269338 'Vps39' mRNA 1147 1192 1082 14.48 14.71 14.72 10.62 10.55 10.66 14.63666667 10.61 984 932 929 1140.333333 948.3333333 0.001434589 -0.277018586 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030897///HOPS complex+++GO:0031902///late endosome membrane+++GO:1902501///lysosomal HOPS complex GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling+++GO:0034058///endosomal vesicle fusion+++GO:0061909///autophagosome-lysosome fusion+++GO:1902774///late endosome to lysosome transport 26934 26934 'Racgap1' mRNA 393 375 376 7.4 6.92 7.46 9.67 10.3 9.97 7.26 9.98 596 621 598 381.3333333 605 2.77E-08 0.654344222 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle+++GO:0090543///Flemming body+++GO:0097149///centralspindlin complex "GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0043014///alpha-tubulin binding+++GO:0043015///gamma-tubulin binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding" GO:0000281///mitotic cytokinesis+++GO:0000915///actomyosin contractile ring assembly+++GO:0006811///ion transport+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007405///neuroblast proliferation+++GO:0008272///sulfate transport+++GO:0030154///cell differentiation+++GO:0032467///positive regulation of cytokinesis+++GO:0035556///intracellular signal transduction+++GO:0045995///regulation of embryonic development+++GO:0050790///regulation of catalytic activity+++GO:0051256///mitotic spindle midzone assembly+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore 269344 269344 'Ell3' mRNA 163 158 135 5.66 5.41 4.98 4.93 5.64 3.88 5.35 4.816666667 163 182 124 152 156.3333333 0.909921546 0.032129184 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex+++GO:0016607///nuclear speck+++GO:0030054///cell junction GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding "GO:0006354///DNA-templated transcription, elongation+++GO:0006366///transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:0050769///positive regulation of neurogenesis+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000179///positive regulation of neural precursor cell proliferation" 269346 269346 'Slc28a2' mRNA 12.7 7.93 6.39 0.28 0.17 0.13 7.47 7.68 7.14 0.193333333 7.43 464.5 464.8 427.06 9.006666667 452.12 2.20E-68 5.750382112 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030135///coated vesicle+++GO:0031526///brush border membrane GO:0005326///neurotransmitter transporter activity+++GO:0005337///nucleoside transmembrane transporter activity+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0015211///purine nucleoside transmembrane transporter activity+++GO:0015213///uridine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015389///pyrimidine- and adenine-specific:sodium symporter activity GO:0001895///retina homeostasis+++GO:0006836///neurotransmitter transport+++GO:0015855///pyrimidine nucleobase transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0015862///uridine transport+++GO:0032238///adenosine transport+++GO:0034394///protein localization to cell surface+++GO:0035340///inosine transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1901642///nucleoside transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport 269356 269356 'Slc4a11' mRNA 277 279 283 4.83 4.69 5.25 23.16 24.2 23.39 4.923333333 23.58333333 1551 1546 1495 279.6666667 1530.666667 1.30E-138 2.440296696 GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0005272///sodium channel activity+++GO:0005372///water transmembrane transporter activity+++GO:0005452///inorganic anion exchanger activity+++GO:0015078///proton transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015252///proton channel activity+++GO:0015293///symporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0046715///active borate transmembrane transporter activity+++GO:0046983///protein dimerization activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0006833///water transport+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0030003///cellular cation homeostasis+++GO:0034599///cellular response to oxidative stress+++GO:0035445///borate transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042044///fluid transport+++GO:0046713///borate transport+++GO:0050801///ion homeostasis+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0055085///transmembrane transport+++GO:0071476///cellular hypotonic response+++GO:0098656///anion transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:2000739///regulation of mesenchymal stem cell differentiation 26936 26936 'Mprip' mRNA 3380.62 3473.58 3156.78 17.28 17.59 17.16 12.29 12.08 13 17.34333333 12.45666667 2763.65 2564.51 2820.01 3336.993333 2716.056667 1.28E-06 -0.307910739 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007015///actin filament organization+++GO:0032507///maintenance of protein location in cell+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity 269378 269378 'Ahcy' mRNA 339.12 325.19 296.81 7.42 7 6.89 7.08 6.33 7.04 7.103333333 6.816666667 372.37 324.85 358.62 320.3733333 351.9466667 0.462610831 0.123722733 00270///Cysteine and methionine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042470///melanosome+++GO:0043005///neuron projection GO:0004013///adenosylhomocysteinase activity+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0030554///adenyl nucleotide binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0051287///NAD binding GO:0002439///chronic inflammatory response to antigenic stimulus+++GO:0006730///one-carbon metabolic process+++GO:0007584///response to nutrient+++GO:0019510///S-adenosylhomocysteine catabolic process+++GO:0033353///S-adenosylmethionine cycle+++GO:0042745///circadian sleep/wake cycle 26938 26938 'St6galnac5' mRNA 6 2 7 0.12 0.04 0.14 0 0.02 0.09 0.1 0.036666667 0 1 5 5 2 0.43679591 -1.343105321 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0009311///oligosaccharide metabolic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0097503///sialylation 269389 269389 'Tox2' mRNA 783 688 520 14.99 13.08 10.71 4.44 4.75 4.78 12.92666667 4.656666667 267 278 277 663.6666667 274 1.29E-19 -1.281094022 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 26939 26939 'Polr3e' mRNA 869 902 982 13.42 13.47 16.34 10.82 11.76 10.99 14.41 11.19 754 770 722 917.6666667 748.6666667 0.005651893 -0.308334707 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0002376///immune system process+++GO:0006351///transcription, DNA-templated+++GO:0045087///innate immune response+++GO:0051607///defense response to virus" 269397 269397 'Ss18l1' mRNA 302 370 244 3.73 4.55 3.35 2 2.32 1.79 3.876666667 2.036666667 181 202 156 305.3333333 179.6666667 3.88E-05 -0.769316155 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0071565///nBAF complex" GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016358///dendrite development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050773///regulation of dendrite development+++GO:0050775///positive regulation of dendrite morphogenesis" 26940 26940 'Ecsit' mRNA 923 1008 976 32.99 35.52 36.29 26.6 28.18 29.68 34.93333333 28.15333333 859 872 920 969 883.6666667 0.178611705 -0.145096093 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding GO:0001707///mesoderm formation+++GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030509///BMP signaling pathway+++GO:0045087///innate immune response+++GO:0051341///regulation of oxidoreductase activity+++GO:0061635///regulation of protein complex stability 269400 269400 'Rtel1' mRNA 389 385 346 4.77 4.63 4.49 3.21 2.84 2.71 4.63 2.92 298 261 246 373.3333333 268.3333333 8.94E-04 -0.48768636 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus" "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0070182///DNA polymerase binding" GO:0000723///telomere maintenance+++GO:0000732///strand displacement+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0031297///replication fork processing+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0043247///telomere maintenance in response to DNA damage+++GO:0045910///negative regulation of DNA recombination+++GO:0061820///telomeric D-loop disassembly+++GO:0090657///telomeric loop disassembly+++GO:1902990///mitotic telomere maintenance via semi-conservative replication+++GO:1904355///positive regulation of telomere capping+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1904430///negative regulation of t-circle formation+++GO:1904506///negative regulation of telomere maintenance in response to DNA damage+++GO:1904535///positive regulation of telomeric loop disassembly 269401 269401 'Zfp512b' mRNA 1015 995 1001 10.46 10.01 10.73 7.62 6.7 7.55 10.4 7.29 865 749 831 1003.666667 815 0.001359547 -0.313861048 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 26941 26941 'Slc9a3r1' mRNA 2172 2151 2043 64.84 63.14 64.61 78.64 72.68 73.52 64.19666667 74.94666667 3030 2732 2740 2122 2834 1.08E-09 0.405239499 "04530///Tight junction+++04928///Parathyroid hormone synthesis, secretion and action+++05130///Pathogenic Escherichia coli infection+++05165///Human papillomavirus infection" GO:0001726///ruffle+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030175///filopodium+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0097225///sperm midpiece+++GO:0098797///plasma membrane protein complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0015185///gamma-aminobutyric acid transmembrane transporter activity+++GO:0017081///chloride channel regulator activity+++GO:0019902///phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0031799///type 2 metabotropic glutamate receptor binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0043495///protein membrane anchor+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding+++GO:0045159///myosin II binding+++GO:0047485///protein N-terminus binding+++GO:0050780///dopamine receptor binding+++GO:0060090///molecular adaptor activity+++GO:0070851///growth factor receptor binding GO:0003096///renal sodium ion transport+++GO:0007009///plasma membrane organization+++GO:0007097///nuclear migration+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0008361///regulation of cell size+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010766///negative regulation of sodium ion transport+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016055///Wnt signaling pathway+++GO:0019933///cAMP-mediated signaling+++GO:0022612///gland morphogenesis+++GO:0030033///microvillus assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030336///negative regulation of cell migration+++GO:0030643///cellular phosphate ion homeostasis+++GO:0032416///negative regulation of sodium:proton antiporter activity+++GO:0032782///bile acid secretion+++GO:0034613///cellular protein localization+++GO:0034635///glutathione transport+++GO:0034767///positive regulation of ion transmembrane transport+++GO:0044062///regulation of excretion+++GO:0044782///cilium organization+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0045859///regulation of protein kinase activity+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051683///establishment of Golgi localization+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0051939///gamma-aminobutyric acid import+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0070293///renal absorption+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090660///cerebrospinal fluid circulation+++GO:0097291///renal phosphate ion absorption+++GO:0098739///import across plasma membrane+++GO:2000146///negative regulation of cell motility+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 26942 26942 'Spag1' mRNA 216.82 236.35 191.29 2.7 2.96 2.55 1.24 1.51 1.99 2.736666667 1.58 118.56 136.6 181.2 214.82 145.4533333 0.00879671 -0.57051818 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0007338///single fertilization+++GO:0070286///axonemal dynein complex assembly 269423 269423 'Abhd18' mRNA 394 409 436 5.11 5.27 5.99 2.53 2.9 3 5.456666667 2.81 223.13 253 257 413 244.3766667 3.19E-07 -0.770392462 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 269424 269424 'Jade1' mRNA 1387 1462 1310 13.36 13.8 13.35 9.47 8.74 8.79 13.50333333 9 1129 1020 1016 1386.333333 1055 8.40E-07 -0.405330571 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003713///transcription coactivator activity+++GO:0046872///metal ion binding "GO:0006915///apoptotic process+++GO:0043966///histone H3 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 26943 26943 'Serinc3' mRNA 10516 9840 11937 232.19 213.1 279.65 564.31 468.99 516.06 241.6466667 516.4533333 29330 23729 25936 10764.33333 26331.66667 5.83E-18 1.270979567 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002376///immune system process+++GO:0006658///phosphatidylserine metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0009597///detection of virus+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 269437 269437 'Plch1' mRNA 955 962 872 7.46 7.44 7.27 2.01 2.28 2.21 7.39 2.166666667 296 326 311 929.6666667 311 2.40E-49 -1.589469055 00562///Inositol phosphate metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050429///calcium-dependent phospholipase C activity GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0048015///phosphatidylinositol-mediated signaling 26944 26944 'Tinag' mRNA 2 6 7 0.07 0.21 0.28 0.53 0.58 0.4 0.186666667 0.503333333 18 19 13 5 16.66666667 0.041609189 1.717225493 GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008234///cysteine-type peptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion 26945 26945 'Tpsg1' mRNA 1 0 0.45 0.08 0 0.04 0 0 0.15 0.04 0.05 0 0 2 0.483333333 0.666666667 0.863090843 0.890645578 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 26946 26946 'Trpc7' mRNA 10 13 3 0.16 0.2 0.05 0 0 0.01 0.136666667 0.003333333 0 0 1 8.666666667 0.333333333 0.008219814 -4.584506155 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005801///cis-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034703///cation channel complex+++GO:0048471///perinuclear region of cytoplasm "GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0015279///store-operated calcium channel activity+++GO:0070679///inositol 1,4,5 trisphosphate binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0007338///single fertilization+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport 269470 269470 'Wdr3' mRNA 500 498 567 7.94 7.78 9.55 9.87 10.47 10.99 8.423333333 10.44333333 716 741 771 521.6666667 742.6666667 4.26E-05 0.494857063 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031965///nuclear membrane+++GO:0032040///small-subunit processome+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome GO:0030515///snoRNA binding GO:0030490///maturation of SSU-rRNA 269473 269473 'Lrig2' mRNA 1493 1386 1411 12.67 11.31 12.17 6.56 5.09 6.49 12.05 6.046666667 922 719 853 1430 831.3333333 2.73E-16 -0.796749696 04360///Axon guidance GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097708///intracellular vesicle GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0007605///sensory perception of sound+++GO:0010640///regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:0048679///regulation of axon regeneration+++GO:0048681///negative regulation of axon regeneration+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0060384///innervation+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2001222///regulation of neuron migration 26949 26949 'Vat1' mRNA 2570 2618 550 52.03 52.17 11.81 24.96 39.9 35.53 38.67 33.46333333 1418 2214 1955 1912.666667 1862.333333 0.992070455 -0.017048514 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity GO:0010637///negative regulation of mitochondrial fusion 26950 26950 'Vsnl1' mRNA 19 12 6 0.62 0.37 0.22 0.06 0.06 0.03 0.403333333 0.05 2 2 1 12.33333333 1.666666667 0.011466419 -2.884696577 GO:0005829///cytosol+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045921///positive regulation of exocytosis+++GO:0046676///negative regulation of insulin secretion 26951 26951 'Zw10' mRNA 692 748 714 13.15 13.98 14.38 12.46 11.48 12.58 13.83666667 12.17333333 755 679 738 718 724 0.998591786 -6.87E-04 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005819///spindle+++GO:0005828///kinetochore microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0070939///Dsl1/NZR complex+++GO:1990423///RZZ complex" GO:0000070///mitotic sister chromatid segregation+++GO:0000132///establishment of mitotic spindle orientation+++GO:0000278///mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007096///regulation of exit from mitosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division+++GO:0065003///protein-containing complex assembly+++GO:0072413///signal transduction involved in mitotic cell cycle checkpoint 269513 269513 'Nkain3' mRNA 46.98 35 48.07 0.45 0.38 0.5 0.08 0.04 0.1 0.443333333 0.073333333 8.99 5 12.01 43.35 8.666666667 1.40E-05 -2.385696297 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002028///regulation of sodium ion transport 269514 269514 'Fbxl4' mRNA 1186 1142 1123 26.05 24.65 26.14 12.53 13.04 14.04 25.61333333 13.20333333 656 667 713 1150.333333 678.6666667 7.43E-17 -0.772729019 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0016607///nuclear speck+++GO:0019005///SCF ubiquitin ligase complex GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 269523 269523 'Vcp' mRNA 7489 8117 8046 123.27 131.46 140.48 151.52 152.55 154.01 131.7366667 152.6933333 10593 10417 10427 7884 10479 1.11E-10 0.397198303 04141///Protein processing in endoplasmic reticulum+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05134///Legionellosis GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0032991///protein-containing complex+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0035861///site of double-strand break+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:1904949///ATPase complex+++GO:1990730///VCP-NSFL1C complex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0042288///MHC class I protein binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:1904288///BAT3 complex binding+++GO:1990381///ubiquitin-specific protease binding "GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006734///NADH metabolic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010498///proteasomal protein catabolic process+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0016236///macroautophagy+++GO:0016567///protein ubiquitination+++GO:0019079///viral genome replication+++GO:0019985///translesion synthesis+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0031334///positive regulation of protein complex assembly+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032510///endosome to lysosome transport via multivesicular body sorting pathway+++GO:0034605///cellular response to heat+++GO:0035617///stress granule disassembly+++GO:0036297///interstrand cross-link repair+++GO:0036503///ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0046034///ATP metabolic process+++GO:0050807///regulation of synapse organization+++GO:0051228///mitotic spindle disassembly+++GO:0061857///endoplasmic reticulum stress-induced pre-emptive quality control+++GO:0070842///aggresome assembly+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0072389///flavin adenine dinucleotide catabolic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097352///autophagosome maturation+++GO:1903006///positive regulation of protein K63-linked deubiquitination+++GO:1903007///positive regulation of Lys63-specific deubiquitinase activity+++GO:1903715///regulation of aerobic respiration+++GO:1903843///cellular response to arsenite ion+++GO:1903862///positive regulation of oxidative phosphorylation+++GO:1905634///regulation of protein localization to chromatin+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000158///positive regulation of ubiquitin-specific protease activity+++GO:2001171///positive regulation of ATP biosynthetic process" 269529 269529 'Fbxo10' mRNA 756 796 762 8.89 9.09 9.41 7.25 5.37 6.24 9.13 6.286666667 715 522 596 771.3333333 611 0.004279507 -0.350775849 GO:0005737///cytoplasm GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0042981///regulation of apoptotic process 269536 269536 'Tex10' mRNA 497.89 509.53 413.24 9.13 9.27 7.95 10.16 10.16 8.78 8.783333333 9.7 648.16 637.26 546.63 473.5533333 610.6833333 0.004200227 0.359159038 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0071339///MLL1 complex 269582 269582 'Clspn' mRNA 4 9 7 0.04 0.1 0.08 0.76 0.89 0.79 0.073333333 0.813333333 84 96 85 6.666666667 88.33333333 1.07E-15 3.718090969 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus GO:0000217///DNA secondary structure binding+++GO:0003677///DNA binding+++GO:0010997///anaphase-promoting complex binding GO:0000076///DNA replication checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0033314///mitotic DNA replication checkpoint 269585 269585 'Zscan20' mRNA 210.43 259.11 189.14 1.59 2.04 1.6 1.05 0.82 0.98 1.743333333 0.95 158.25 127.92 137.9 219.56 141.3566667 0.001129893 -0.649701905 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 269587 269587 'Epb41' mRNA 2262.26 2338.81 2270.64 21.6 21.89 23.22 12.93 12.6 11.91 22.23666667 12.48 1548.86 1459.53 1387.73 2290.57 1465.373333 2.87E-19 -0.657513967 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0030863///cortical cytoskeleton+++GO:0032991///protein-containing complex+++GO:0033588///Elongator holoenzyme complex+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle+++GO:0099738///cell cortex region GO:0000049///tRNA binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0008022///protein C-terminus binding+++GO:0008092///cytoskeletal protein binding+++GO:0030507///spectrin binding+++GO:0047485///protein N-terminus binding+++GO:0051219///phosphoprotein binding GO:0001558///regulation of cell growth+++GO:0002098///tRNA wobble uridine modification+++GO:0002926///tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007252///I-kappaB phosphorylation+++GO:0008033///tRNA processing+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031032///actomyosin structure organization+++GO:0032092///positive regulation of protein binding+++GO:0051301///cell division+++GO:0051924///regulation of calcium ion transport+++GO:0065003///protein-containing complex assembly+++GO:1904478///regulation of intestinal absorption+++GO:1904778///positive regulation of protein localization to cell cortex 269589 269589 'Sytl1' mRNA 111 142 141 3.3 4.2 4.46 3.38 2.66 3.19 3.986666667 3.076666667 131 99 119 131.3333333 116.3333333 0.508887167 -0.191027403 GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0042470///melanosome+++GO:0070382///exocytic vesicle GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042043///neurexin family protein binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0016192///vesicle-mediated transport 269593 269593 'Luzp1' mRNA 1030.93 1076.32 1045.35 7.41 7.69 8.04 10.34 10.38 11.12 7.713333333 10.61333333 1662.39 1631.27 1726.88 1050.866667 1673.513333 1.60E-16 0.659559902 GO:0005634///nucleus GO:0003674///molecular_function GO:0003281///ventricular septum development+++GO:0021503///neural fold bending+++GO:0060840///artery development 269604 269604 'Gpr157' mRNA 208.97 194.69 279.12 2.43 2.23 3.51 3.83 2.96 3.35 2.723333333 3.38 382.69 291.59 329.57 227.5933333 334.6166667 0.00655052 0.534541688 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0048512///circadian behavior+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060019///radial glial cell differentiation 269608 269608 'Plekhg5' mRNA 934 980 847 12.84 13.32 12.53 7.88 7.5 8.47 12.89666667 7.95 661 612 685 920.3333333 652.6666667 2.19E-07 -0.505803524 05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding "GO:0007266///Rho protein signal transduction+++GO:0035767///endothelial cell chemotaxis+++GO:0043542///endothelial cell migration+++GO:0050790///regulation of catalytic activity+++GO:0099575///regulation of protein catabolic process at presynapse, modulating synaptic transmission" 26961 26961 'Rpl8' mRNA 3916 4076 3624 302.35 311.67 296.92 384.46 377.93 406.09 303.6466667 389.4933333 5703 5461 5818 3872 5660.666667 2.59E-22 0.537583564 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0019843///rRNA binding GO:0002181///cytoplasmic translation+++GO:0006412///translation 269610 269610 'Chd5' mRNA 207 248 246 1.18 1.39 1.45 0.19 0.25 0.2 1.34 0.213333333 40 50 39 233.6666667 43 2.94E-25 -2.454859591 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016581///NuRD complex+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0061628///H3K27me3 modified histone binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030154///cell differentiation+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0043967///histone H4 acetylation+++GO:0045595///regulation of cell differentiation+++GO:0098532///histone H3-K27 trimethylation+++GO:1901798///positive regulation of signal transduction by p53 class mediator" 269614 269614 'Pank4' mRNA 813 794 935 17.54 16.85 21.39 15.36 12.65 14.38 18.59333333 14.13 820 659 743 847.3333333 740.6666667 0.107526255 -0.212236164 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004594///pantothenate kinase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation 269615 269615 'Plch2' mRNA 443 512 453 4.36 4.94 4.73 0.65 0.66 0.52 4.676666667 0.61 79 76 59 469.3333333 71.33333333 5.19E-55 -2.729414069 00562///Inositol phosphate metabolism GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0046488///phosphatidylinositol metabolic process+++GO:0048015///phosphatidylinositol-mediated signaling 269623 269623 'Rbm48' mRNA 386.74 410.91 408.62 9.18 9.51 10.26 6.15 5.92 5.89 9.65 5.986666667 298.49 270.84 275.92 402.09 281.75 1.88E-04 -0.527731382 GO:0005654///nucleoplasm GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0008150///biological_process 269629 269629 'Lhfpl3' mRNA 5 8 3 0.09 0.14 0.06 0 0.03 0 0.096666667 0.01 0 2 0 5.333333333 0.666666667 0.111599357 -2.984243826 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007605///sensory perception of sound 269633 269633 'Wdr86' mRNA 983 1005 926 27.3 27.49 27.44 41.5 41.93 42.06 27.41 41.83 1689 1674 1666 971.3333333 1676.333333 2.58E-24 0.776491793 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 269637 269637 'Cnpy1' mRNA 2 0 2 0.04 0 0.04 0.02 0 0 0.026666667 0.006666667 1 0 0 1.333333333 0.333333333 0.596502362 -1.930061185 GO:0005783///endoplasmic reticulum GO:0003674///molecular_function 269639 269639 'Zfp512' mRNA 1037 1119 1051 17.32 18.33 18.8 11.58 11.13 10.41 18.15 11.04 802 750 695 1069 749 3.32E-08 -0.525594023 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 269642 269642 'Nat8l' mRNA 25 25 20 0.2 0.2 0.17 0.27 0.36 0.3 0.19 0.31 39 50 41 23.33333333 43.33333333 0.050067419 0.886829155 "00250///Alanine, aspartate and glutamate metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0017188///aspartate N-acetyltransferase activity" GO:0051586///positive regulation of dopamine uptake involved in synaptic transmission 269643 269643 'Ppp2r2c' mRNA 769 720 601 10.34 9.43 8.66 4.88 5.16 5.33 9.476666667 5.123333333 415 426 439 696.6666667 426.6666667 8.76E-10 -0.715008559 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005829///cytosol GO:0019888///protein phosphatase regulator activity GO:0050790///regulation of catalytic activity+++GO:0070262///peptidyl-serine dephosphorylation 26965 26965 'Cul1' mRNA 2043 2079 1845 35.79 35.72 34.35 28.85 30.8 28.73 35.28666667 29.46 1905 1980 1828 1989 1904.333333 0.405809715 -0.072369289 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway+++04710///Circadian rhythm+++05131///Shigellosis+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:1990452///Parkin-FBXW7-Cul1 ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006915///apoptotic process+++GO:0008283///cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0016032///viral process+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 26968 26968 'Islr' mRNA 1544 1525 1665 40.4 39.14 45.67 42.29 42 43.91 41.73666667 42.73333333 1860 1794 1858 1578 1837.333333 0.022770248 0.204804289 GO:0005576///extracellular region+++GO:0005615///extracellular space 269682 269682 'Golga3' mRNA 751 868 742 4.9 5.59 5.15 5.8 5.06 4.69 5.213333333 5.183333333 1023 872 805 787 900 0.12822025 0.181789207 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0017119///Golgi transport complex+++GO:0032580///Golgi cisterna membrane+++GO:0090498///extrinsic component of Golgi membrane GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 269693 269693 'Ccdc60' mRNA 373 300 322.08 8.34 6.6 7.65 0.49 0.92 0.6 7.53 0.67 23 42 27.97 331.6933333 30.99 7.19E-46 -3.444853325 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 269695 269695 'Rnft2' mRNA 146.64 165.36 148.93 1.22 1.2 1.04 0.89 0.96 1.05 1.153333333 0.966666667 145.62 149.2 141.31 153.6433333 145.3766667 0.748901072 -0.088226393 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:1904294///positive regulation of ERAD pathway 26970 26970 'Pla2g2e' mRNA 23 25 8 1.81 1.94 0.67 3.98 3.1 2.77 1.473333333 3.283333333 58 44 39 18.66666667 47 0.007442898 1.333151273 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005737///cytoplasm "GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006954///inflammatory response+++GO:0016042///lipid catabolic process+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0050482///arachidonic acid secretion 269700 269700 'Hectd4' mRNA 1155 1163 1151 3.9 3.85 4.15 2.71 2.38 2.59 3.966666667 2.56 932 792 857 1156.333333 860.3333333 2.02E-06 -0.440158511 GO:0004842///ubiquitin-protein transferase activity GO:0006006///glucose metabolic process+++GO:0016567///protein ubiquitination+++GO:0042593///glucose homeostasis 269701 269701 'Wdr66' mRNA 446 487 388 4.86 5.2 4.44 0.55 0.38 0.42 4.833333333 0.45 57 39 43 440.3333333 46.33333333 1.10E-62 -3.25834605 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030317///flagellated sperm motility 269702 269702 'Mphosph9' mRNA 507 493 509 3.92 4.42 4.14 2.42 1.84 2.29 4.16 2.183333333 335 256 333 503 308 2.97E-07 -0.72231165 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 269704 269704 'Zfp664' mRNA 2539 2722 2155 33.57 35.4 30.23 21.86 17.62 20.88 33.06666667 20.12 1903 1498 1760 2472 1720.333333 1.38E-09 -0.532521147 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 26971 26971 'Pla2g2f' mRNA 4 10 1 0.11 0.33 0.03 0.19 0 0.1 0.156666667 0.096666667 4 0 1 5 1.666666667 0.381314498 -1.58282104 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0002376///immune system process+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0042130///negative regulation of T cell proliferation+++GO:0045087///innate immune response+++GO:0050482///arachidonic acid secretion 269713 269713 'Clip2' mRNA 365.73 394 189.47 3.95 4.17 2.18 1.82 1.67 1.95 3.433333333 1.813333333 194.89 173.67 203.5 316.4 190.6866667 0.001122672 -0.732072152 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0035371///microtubule plus-end+++GO:0042599///lamellar body+++GO:0042995///cell projection+++GO:0044354///macropinosome+++GO:1901588///dendritic microtubule GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051010///microtubule plus-end binding GO:0001578///microtubule bundle formation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0044861///protein transport into plasma membrane raft+++GO:1900006///positive regulation of dendrite development 269717 269717 'Orai2' mRNA 675 741 684 8.92 9.62 9.77 4.75 4.79 3.7 9.436666667 4.413333333 414 396 310 700 373.3333333 6.25E-13 -0.91913823 04020///Calcium signaling pathway GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone GO:0015279///store-operated calcium channel activity GO:0002115///store-operated calcium entry+++GO:0070588///calcium ion transmembrane transport 26972 26972 'Spo11' mRNA 13 15 11 0.26 0.32 0.36 0.17 0.34 0.2 0.313333333 0.236666667 7 17 11 13 11.66666667 0.863090843 -0.156896549 "GO:0000228///nuclear chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" "GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0003918///DNA topoisomerase type II (ATP-hydrolyzing) activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0016889///endodeoxyribonuclease activity, producing 3'-phosphomonoesters+++GO:0046872///metal ion binding" GO:0000237///leptotene+++GO:0000706///meiotic DNA double-strand break processing+++GO:0001541///ovarian follicle development+++GO:0006259///DNA metabolic process+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0007141///male meiosis I+++GO:0007286///spermatid development+++GO:0034502///protein localization to chromosome+++GO:0042138///meiotic DNA double-strand break formation+++GO:0045141///meiotic telomere clustering+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:1990918///double-strand break repair involved in meiotic recombination 269774 269774 'Aak1' mRNA 1850 1928 1509 10.08 10.34 8.6 5.21 4.47 5.06 9.673333333 4.913333333 1147 958 1081 1762.333333 1062 2.08E-16 -0.739271098 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0045202///synapse+++GO:0071439///clathrin complex+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005112///Notch binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035612///AP-2 adaptor complex binding GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0016310///phosphorylation+++GO:0032880///regulation of protein localization+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:2000369///regulation of clathrin-dependent endocytosis 269784 269784 'Cntn4' mRNA 416 393 372 4.93 4.51 4.35 1.16 0.93 1.23 4.596666667 1.106666667 122 98 109 393.6666667 109.6666667 6.91E-30 -1.855956362 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0031175///neuron projection development+++GO:0045665///negative regulation of neuron differentiation 269788 269788 'Lhfpl4' mRNA 702 708 571 7.89 7.82 6.8 0.94 0.63 1.12 7.503333333 0.896666667 96 63 111 660.3333333 90 3.06E-65 -2.884414991 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060077///inhibitory synapse GO:0005515///protein binding+++GO:0050811///GABA receptor binding GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:1905702///regulation of inhibitory synapse assembly 269799 269799 'Clec4a1' mRNA 124 133 127 4.68 4.95 5.08 23.34 24.15 22.67 4.903333333 23.38666667 711 718 668 128 699 2.74E-72 2.437771612 GO:0005575///cellular_component+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding "GO:0001818///negative regulation of cytokine production+++GO:0002470///plasmacytoid dendritic cell antigen processing and presentation+++GO:0006955///immune response+++GO:0008150///biological_process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0044419///interspecies interaction between organisms+++GO:0061760///antifungal innate immune response" 269800 269800 'Zfp384' mRNA 351 264 320 5.91 4.37 5.91 8.13 5.48 9.38 5.396666667 7.663333333 547 360 607 311.6666667 504.6666667 2.88E-04 0.678378088 04361///Axon regeneration GO:0005634///nucleus+++GO:0005925///focal adhesion "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0017124///SH3 domain binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006913///nucleocytoplasmic transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050714///positive regulation of protein secretion 269823 269823 'Pon3' mRNA 264.33 257.15 229.69 2.21 2.13 2.06 9.58 9.65 8.99 2.133333333 9.406666667 977.09 871.94 867 250.39 905.3433333 2.32E-60 1.845022042 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle "GO:0004063///aryldialkylphosphatase activity+++GO:0004064///arylesterase activity+++GO:0016787///hydrolase activity+++GO:0018733///3,4-dihydrocoumarin hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0102007///acyl-L-homoserine-lactone lactonohydrolase activity" GO:0003096///renal sodium ion transport+++GO:0009636///response to toxic substance+++GO:0010124///phenylacetate catabolic process+++GO:0016311///dephosphorylation+++GO:0019439///aromatic compound catabolic process+++GO:0032929///negative regulation of superoxide anion generation+++GO:0046226///coumarin catabolic process+++GO:0046395///carboxylic acid catabolic process+++GO:0051649///establishment of localization in cell 269831 269831 'Tspan12' mRNA 4617 4552 4554 105.22 101.84 110.06 34.67 34.92 34.99 105.7066667 34.86 1758 1716 1699 4574.333333 1724.333333 2.32E-111 -1.420231739 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042813///Wnt-activated receptor activity GO:0001525///angiogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0010842///retina layer formation+++GO:0016055///Wnt signaling pathway+++GO:0045765///regulation of angiogenesis+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway 269854 269854 'Nat14' mRNA 941 1035 906 40.91 45.74 42.77 15.15 15.39 15.45 43.14 15.33 384 385 380 960.6666667 383 3.66E-39 -1.336899664 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003677///DNA binding+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0008150///biological_process 269855 269855 'Ssc5d' mRNA 61 65 54 0.76 0.8 0.71 1.56 1.15 1.34 0.756666667 1.35 144 104 120 60 122.6666667 1.45E-04 1.019845031 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0043236///laminin binding+++GO:0050840///extracellular matrix binding GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0006952///defense response+++GO:0007275///multicellular organism development+++GO:0032677///regulation of interleukin-8 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0042494///detection of bacterial lipoprotein+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 26987 26987 'Eif4e2' mRNA 778.1 780.87 748 15.2 15.26 15.19 29.5 30.88 34.91 15.21666667 31.76333333 1204.65 1272.02 1323 768.99 1266.556667 4.18E-15 0.709470085 01521///EGFR tyrosine kinase inhibitor resistance+++04066///HIF-1 signaling pathway+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04211///Longevity regulating pathway+++04910///Insulin signaling pathway GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005845///mRNA cap binding complex+++GO:0016281///eukaryotic translation initiation factor 4F complex GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0001701///in utero embryonic development+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA+++GO:1905618///positive regulation of miRNA mediated inhibition of translation 269870 269870 'Zfp446' mRNA 834 800 869.1 12.08 11.14 13.07 3.97 3.78 4.29 12.09666667 4.013333333 325 290 330.01 834.3666667 315.0033333 1.32E-33 -1.420030076 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 269878 269878 'Megf8' mRNA 3071 3003 2488 16.01 15.39 13.76 7.89 6.95 7.54 15.05333333 7.46 1744 1501 1614 2854 1619.666667 2.31E-27 -0.826443546 04340///Hedgehog signaling pathway GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0003143///embryonic heart tube morphogenesis+++GO:0007368///determination of left/right symmetry+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0010468///regulation of gene expression+++GO:0030326///embryonic limb morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0035108///limb morphogenesis+++GO:0042074///cell migration involved in gastrulation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048842///positive regulation of axon extension involved in axon guidance+++GO:0055113///epiboly involved in gastrulation with mouth forming second+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0060972///left/right pattern formation+++GO:0060976///coronary vasculature development+++GO:0061371///determination of heart left/right asymmetry+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0097094///craniofacial suture morphogenesis+++GO:0097155///fasciculation of sensory neuron axon+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry 269881 269881 'Map3k10' mRNA 36 57 22 0.51 0.8 0.34 0.59 0.53 0.55 0.55 0.556666667 47 42 42 38.33333333 43.66666667 0.740213982 0.189634102 05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003714///transcription corepressor activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043425///bHLH transcription factor binding "GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007224///smoothened signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0008219///cell death+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade" 269902 269902 'Vmn2r57' mRNA 5 8 7 0.11 0.17 0.16 0.09 0.04 0.08 0.146666667 0.07 5 2 4 6.666666667 3.666666667 0.49766456 -0.880396539 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 26992 26992 'Brd7' mRNA 558 514 593 10.07 8.96 11.52 11.05 11.69 10.48 10.18333333 11.07333333 712 714 650 555 692 0.015304356 0.303306411 05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0070603///SWI/SNF superfamily-type complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042393///histone binding+++GO:0070577///lysine-acetylated histone binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0035066///positive regulation of histone acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 269941 269941 'Chsy1' mRNA 473 506 592 6.88 7.23 9.18 9.7 8.7 9.34 7.763333333 9.246666667 763 670 715 523.6666667 716 9.74E-04 0.433589873 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0050510///N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity" GO:0002063///chondrocyte development+++GO:0009954///proximal/distal pattern formation+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0030279///negative regulation of ossification+++GO:0031667///response to nutrient levels+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051216///cartilage development+++GO:0051923///sulfation+++GO:0060349///bone morphogenesis 269951 269951 'Idh2' mRNA 2996 2970 2769 100.54 98.31 98.94 116.72 120.88 114.5 99.26333333 117.3666667 3968 4005 3773 2911.666667 3915.333333 8.14E-12 0.41654311 00020///Citrate cycle (TCA cycle)+++00480///Glutathione metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids+++04146///Peroxisome+++05230///Central carbon metabolism in cancer GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0005829///cytosol "GO:0000287///magnesium ion binding+++GO:0004448///isocitrate dehydrogenase activity+++GO:0004450///isocitrate dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0046872///metal ion binding+++GO:0051287///NAD binding" GO:0006097///glyoxylate cycle+++GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006739///NADP metabolic process+++GO:0006741///NADP biosynthetic process+++GO:0060253///negative regulation of glial cell proliferation+++GO:1903976///negative regulation of glial cell migration+++GO:1904465///negative regulation of matrix metallopeptidase secretion 269952 269952 'Gdpgp1' mRNA 266.98 256.01 261.9 4.12 3.89 4.29 3.6 3.38 3.73 4.1 3.57 268 245.82 269.08 261.63 260.9666667 0.944927237 -0.014763799 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0080048///GDP-D-glucose phosphorylase activity GO:0006006///glucose metabolic process+++GO:0050790///regulation of catalytic activity 269954 269954 'Ttll13' mRNA 96 111 82 1.67 1.91 1.49 0.36 0.47 0.3 1.69 0.376666667 25 31 19 96.33333333 25 9.82E-09 -1.952183376 GO:0005874///microtubule+++GO:0005929///cilium GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation 269955 269955 'Rccd1' mRNA 197 163 198 4.58 3.75 4.9 3.66 3.23 3.33 4.41 3.406666667 178 155 165 186 166 0.445743958 -0.180074637 GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0006325///chromatin organization+++GO:0008150///biological_process 269959 269959 'Adamtsl3' mRNA 21 28 22 0.15 0.19 0.17 0.23 0.31 0.27 0.17 0.27 36 49 42 23.66666667 42.33333333 0.072202662 0.832030049 GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0004222///metalloendopeptidase activity GO:0030198///extracellular matrix organization 269966 269966 'Nup98' mRNA 1122.7 1104.19 1305.26 10 9.85 12.11 13.14 11.18 12.14 10.65333333 12.15333333 1747.48 1421.31 1565.33 1177.383333 1578.04 2.09E-04 0.404247812 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031080///nuclear pore outer ring+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery+++GO:0042405///nuclear inclusion body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044615///nuclear pore nuclear basket+++GO:1990904///ribonucleoprotein complex GO:0003713///transcription coactivator activity+++GO:0003729///mRNA binding+++GO:0008139///nuclear localization sequence binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017056///structural constituent of nuclear pore+++GO:0042277///peptide binding+++GO:1990841///promoter-specific chromatin binding "GO:0006508///proteolysis+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly" 269994 269994 'Gsg1l' mRNA 21 25 7 0.31 0.36 0.11 0.05 0.04 0.01 0.26 0.033333333 4 3 1 17.66666667 2.666666667 0.004447043 -2.721482241 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032279///asymmetric synapse+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0003674///molecular_function GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:2000311///regulation of AMPA receptor activity 269997 269997 'Zfp747' mRNA 314.19 326.36 276.57 6.48 6.63 6.05 5 4.85 4.48 6.386666667 4.776666667 278.75 264.24 241.98 305.7066667 261.6566667 0.156760602 -0.236085969 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 269999 269999 'Orai3' mRNA 964 1008 972 27.5 28.33 29.42 31.94 29.92 30.18 28.41666667 30.68 1287 1177 1177 981.3333333 1213.666667 9.09E-04 0.293845903 04020///Calcium signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015279///store-operated calcium channel activity GO:0002115///store-operated calcium entry+++GO:0070588///calcium ion transmembrane transport 270004 270004 'Foxi2' mRNA 0 4 0 0 0.08 0 0.04 0 0 0.026666667 0.013333333 2 0 0 1.333333333 0.666666667 0.811660001 -0.993661767 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation" 270028 270028 'Fam155a' mRNA 4.06 5.56 9.03 0.01 0.02 0.06 0.05 0.07 0.04 0.03 0.053333333 8 8.95 5.92 6.216666667 7.623333333 0.872700717 0.195257049 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0015275///stretch-activated, cation-selective, calcium channel activity" GO:0098703///calcium ion import across plasma membrane 270035 270035 'Letm2' mRNA 529 513 428 10.47 10.62 9.43 4.9 5.62 5.14 10.17333333 5.22 274 304 274 490 284 4.27E-09 -0.794434006 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0043022///ribosome binding GO:0006875///cellular metal ion homeostasis 270049 270049 'Galntl6' mRNA 4 6 5.21 0.03 0.04 0.05 0.02 0.02 0.04 0.04 0.026666667 2 3 5 5.07 3.333333333 0.704984002 -0.592754613 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0018243///protein O-linked glycosylation via threonine 270058 270058 'Map1s' mRNA 1037 1009 907 17.11 16.31 15.97 19.74 19.48 20.12 16.46333333 19.78 1378 1326 1357 984.3333333 1353.666667 3.76E-08 0.449509685 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0042802///identical protein binding+++GO:0048487///beta-tubulin binding+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0010848///regulation of chromatin disassembly+++GO:0016358///dendrite development+++GO:0031114///regulation of microtubule depolymerization+++GO:0048812///neuron projection morphogenesis 270066 270066 'Slc35e1' mRNA 466.01 482 482.13 3.53 3.58 3.84 3.86 3.82 4.45 3.65 4.043333333 589.01 569.58 659 476.7133333 605.8633333 0.007271152 0.333025899 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity GO:0055085///transmembrane transport 27007 27007 'Klrk1' mRNA 40 36 47 0.92 0.65 1.05 1.89 2.54 1.67 0.873333333 2.033333333 111 90 82 41 94.33333333 1.93E-04 1.183774745 04650///Natural killer cell mediated cytotoxicity+++05144///Malaria GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0030246///carbohydrate binding+++GO:0032394///MHC class Ib receptor activity+++GO:0038023///signaling receptor activity+++GO:0042288///MHC class I protein binding+++GO:0042802///identical protein binding GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0030101///natural killer cell activation+++GO:0030154///cell differentiation+++GO:0030887///positive regulation of myeloid dendritic cell activation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071222///cellular response to lipopolysaccharide 270076 270076 'Gcdh' mRNA 1104.79 1079.92 1067.61 27.46 26.31 28.31 21.13 19.41 17.8 27.36 19.44666667 946.09 848.6 780.63 1084.106667 858.44 3.83E-04 -0.349618208 00071///Fatty acid degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0000062///fatty-acyl-CoA binding+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004361///glutaryl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding" GO:0006568///tryptophan metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0019395///fatty acid oxidation+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0046949///fatty-acyl-CoA biosynthetic process 27008 27008 'Micall1' mRNA 971.66 972.22 880.63 7.63 7.49 7.34 6.8 7.54 7.55 7.486666667 7.296666667 993.37 1078.56 1069.92 941.5033333 1047.283333 0.157433176 0.144117128 GO:0005768///endosome+++GO:0005770///late endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031902///late endosome membrane+++GO:0055038///recycling endosome membrane GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070300///phosphatidic acid binding GO:0006612///protein targeting to membrane+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0031175///neuron projection development+++GO:0032456///endocytic recycling+++GO:0032458///slow endocytic recycling+++GO:0036010///protein localization to endosome+++GO:0097320///plasma membrane tubulation+++GO:1990090///cellular response to nerve growth factor stimulus 270084 270084 'Lpcat2' mRNA 1085 1088 1104 21.31 21.04 22.97 23.99 28.19 25.55 21.77333333 25.91 1405 1614 1448 1092.333333 1489 4.05E-06 0.435365432 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding+++GO:0047159///1-alkenylglycerophosphocholine O-acyltransferase activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047192///1-alkylglycerophosphocholine O-acetyltransferase activity+++GO:0050200///plasmalogen synthase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006663///platelet activating factor biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0061024///membrane organization 270086 270086 'Ogfod1' mRNA 765 667 544 7.68 6.58 5.79 4.95 4.62 4.72 6.683333333 4.763333333 568 518 524 658.6666667 536.6666667 0.01931502 -0.30321225 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule "GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0031418///L-ascorbic acid binding+++GO:0031543///peptidyl-proline dioxygenase activity+++GO:0031544///peptidyl-proline 3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006449///regulation of translational termination+++GO:0008283///cell proliferation+++GO:0018126///protein hydroxylation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0034063///stress granule assembly 270091 270091 'Lrrc36' mRNA 11 12 15 0.25 0.3 0.37 0.19 0.3 0.27 0.306666667 0.253333333 7 12 11 12.66666667 10 0.715065126 -0.354836006 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 270096 270096 'Mon1b' mRNA 879 977 951 9.41 10.25 10.75 8.89 8.02 8.34 10.13666667 8.416666667 958 843 871 935.6666667 890.6666667 0.480942705 -0.084877458 GO:0005737///cytoplasm+++GO:0035658///Mon1-Ccz1 complex GO:0003674///molecular_function GO:0006623///protein targeting to vacuole+++GO:0016192///vesicle-mediated transport+++GO:0019085///early viral transcription+++GO:0019086///late viral transcription 270097 270097 'Vat1l' mRNA 167 139 193 2.48 2 3 1.68 1.4 1.75 2.493333333 1.61 132 106 132 166.3333333 123.3333333 0.065666475 -0.451170562 GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity 270106 270106 'Rpl13' mRNA 8582.71 8558.05 7978.58 755.91 747.36 745.73 922.81 927.61 925.88 749.6666667 925.4333333 11989.86 11734.37 11613 8373.113333 11779.07667 3.61E-24 0.481398479 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0001824///blastocyst development+++GO:0006412///translation+++GO:0060348///bone development 270109 270109 'Pcnx2' mRNA 188 186 186 2.14 2.1 2.26 0.05 0.14 0.07 2.166666667 0.086666667 5 14 7 186.6666667 8.666666667 4.49E-33 -4.439138891 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 270110 270110 'Irf2bp2' mRNA 953 938 802 10.02 9.69 8.94 11 9.2 11.69 9.55 10.63 1205 985 1240 897.6666667 1143.333333 0.00130231 0.338803958 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002327///immature B cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II 270118 270118 'Maml2' mRNA 5086.19 4953.11 4378.87 22.84 22.34 21.4 14.4 12.76 13.57 22.19333333 13.57666667 3775.21 3165.93 3388 4806.056667 3443.046667 1.64E-13 -0.492170624 04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0003713///transcription coactivator activity GO:0007219///Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0045944///positive regulation of transcription by RNA polymerase II 270120 270120 'Fat3' mRNA 4 11 7 0.02 0.03 0.02 0.03 0.04 0.02 0.023333333 0.03 7 11 9 7.333333333 9 0.809260148 0.290602388 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite GO:0005509///calcium ion binding GO:0000904///cell morphogenesis involved in differentiation+++GO:0001764///neuron migration+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0010842///retina layer formation+++GO:0098609///cell-cell adhesion+++GO:2000171///negative regulation of dendrite development 27015 27015 'Polk' mRNA 487 417 480 6.11 5.21 6.33 6.08 5.39 5.18 5.883333333 5.55 563 484 456 461.3333333 501 0.538335554 0.103243408 03460///Fanconi anemia pathway+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0090734///site of DNA damage GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding "GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0034644///cellular response to UV+++GO:0042276///error-prone translesion synthesis+++GO:0071897///DNA biosynthetic process" 270150 270150 'Ccdc153' mRNA 0 1 0 0 0.1 0 0 0.09 0.17 0.033333333 0.086666667 0 1 2 0.333333333 1 0.729606046 1.480883484 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 270151 270151 'Nlrx1' mRNA 400 408 291 6.03 6.03 4.68 4.86 5.92 5.15 5.58 5.31 370 439 382 366.3333333 397 0.555722717 0.1119522 04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++05164///Influenza A GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0002376///immune system process+++GO:0016032///viral process+++GO:0032688///negative regulation of interferon-beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0035556///intracellular signal transduction+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0050728///negative regulation of inflammatory response 270152 270152 'Jaml' mRNA 52 57 83 1.3 1.28 1.98 4.96 5.59 5.64 1.52 5.396666667 251 278 272 64 267 1.90E-19 2.042481517 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005178///integrin binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0002376///immune system process+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030593///neutrophil chemotaxis+++GO:0035696///monocyte extravasation+++GO:0046629///gamma-delta T cell activation+++GO:0050900///leukocyte migration+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0072672///neutrophil extravasation 270156 270156 'Nkapd1' mRNA 409 418 349.73 6.22 6.19 6.07 4.64 5.16 4.57 6.16 4.79 326 357 324 392.2433333 335.6666667 0.121998937 -0.231907756 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 270160 270160 'Rab39' mRNA 13 16 10 0.24 0.29 0.2 0.64 0.51 0.83 0.243333333 0.66 40 31 50 13 40.33333333 0.001524238 1.626599539 GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0090383///phagosome acidification+++GO:0090385///phagosome-lysosome fusion 270162 270162 'Elmod1' mRNA 731 750 728 15.14 15.21 15.76 0.85 0.8 1.06 15.37 0.903333333 49 45 56 736.3333333 50 4.81E-120 -3.892682614 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005096///GTPase activator activity GO:0043547///positive regulation of GTPase activity 270163 270163 'Myo9a' mRNA 1574 1623 1265 6.8 6.87 5.83 4.73 3.97 4.34 6.5 4.346666667 1257 1033 1116 1487.333333 1135.333333 3.27E-05 -0.398349881 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016459///myosin complex+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0044295///axonal growth cone+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005096///GTPase activator activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0034329///cell junction assembly+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0150011///regulation of neuron projection arborization 270166 270166 'Clpx' mRNA 1383 1398 1342 26.45 26.32 27.24 23.38 24.65 25.33 26.67 24.45333333 1405 1448 1474 1374.333333 1442.333333 0.561119339 0.058469366 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0009368///endopeptidase Clp complex+++GO:0009841///mitochondrial endopeptidase Clp complex+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016504///peptidase activator activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0006508///proteolysis+++GO:0010952///positive regulation of peptidase activity+++GO:0030163///protein catabolic process+++GO:0046034///ATP metabolic process+++GO:0051603///proteolysis involved in cellular protein catabolic process 270190 270190 'Ephb1' mRNA 838 922 263 9.66 10.62 3.21 0.77 1.06 1.26 7.83 1.03 76 103 122 674.3333333 100.3333333 1.15E-06 -2.732456314 04360///Axon guidance+++04361///Axon regeneration GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031901///early endosome membrane+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005003///ephrin receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008046///axon guidance receptor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0001771///immunological synapse formation+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0014719///skeletal muscle satellite cell activation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021545///cranial nerve development+++GO:0021631///optic nerve morphogenesis+++GO:0021934///hindbrain tangential cell migration+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0022008///neurogenesis+++GO:0030010///establishment of cell polarity+++GO:0031290///retinal ganglion cell axon guidance+++GO:0031589///cell-substrate adhesion+++GO:0033674///positive regulation of kinase activity+++GO:0046328///regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0048593///camera-type eye morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051965///positive regulation of synapse assembly+++GO:0060326///cell chemotaxis+++GO:0060996///dendritic spine development+++GO:0060997///dendritic spine morphogenesis+++GO:0061351///neural precursor cell proliferation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1901214///regulation of neuron death+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation+++GO:1902725///negative regulation of satellite cell differentiation 270192 270192 'Rab6b' mRNA 354 391 199 4.85 4.79 2.68 0.82 1.24 1.09 4.106666667 1.05 77 86 83 314.6666667 82 3.66E-17 -1.937918117 GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031489///myosin V binding "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi" 270198 270198 'Pfkfb4' mRNA 622 627.87 567 10.18 10.07 9.87 7.09 7.03 7.04 10.04 7.053333333 501.03 495.01 493.57 605.6233333 496.5366667 0.00920734 -0.296773654 00051///Fructose and mannose metabolism+++04152///AMPK signaling pathway GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003873///6-phosphofructo-2-kinase activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity" "GO:0006000///fructose metabolic process+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0046835///carbohydrate phosphorylation" 270201 270201 'Klhl18' mRNA 408 498 427 5.27 6.22 5.7 5.89 5.53 5.53 5.73 5.65 537 489 487 444.3333333 504.3333333 0.226245923 0.171403597 GO:0005515///protein binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:1901992///positive regulation of mitotic cell cycle phase transition 270210 270210 'Zfp651' mRNA 1591 1540 1553 17.03 16.21 17.64 9.86 8.57 9.46 16.96 9.296666667 1057 896 985 1561.333333 979.3333333 1.11E-15 -0.686619168 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 27027 27027 'Tspan32' mRNA 7 7 11 0.27 0.25 0.41 7.47 8.05 8.67 0.31 8.063333333 241 253 271 8.333333333 255 3.57E-44 4.922988918 GO:0005622///intracellular+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070442///integrin alphaIIb-beta3 complex GO:0003674///molecular_function GO:0007010///cytoskeleton organization+++GO:0007229///integrin-mediated signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008285///negative regulation of cell proliferation+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0042832///defense response to protozoan+++GO:0050688///regulation of defense response to virus+++GO:0051604///protein maturation+++GO:0070527///platelet aggregation+++GO:0072659///protein localization to plasma membrane 27028 27028 'Ermap' mRNA 7.02 9.23 4.63 0.08 0.1 0.06 0.25 0.2 0.12 0.08 0.19 24.15 19.01 11 6.96 18.05333333 0.070504995 1.428366496 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 27029 27029 'Sgsh' mRNA 566.8 525.93 577.13 7.05 6.43 7.61 11.69 11.13 10.85 7.03 11.22333333 1082.18 1006.09 973.22 556.62 1020.496667 5.34E-17 0.861498129 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005764///lysosome GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0005539///glycosaminoglycan binding+++GO:0008449///N-acetylglucosamine-6-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016250///N-sulfoglucosamine sulfohydrolase activity+++GO:0016787///hydrolase activity GO:0006027///glycosaminoglycan catabolic process+++GO:0030200///heparan sulfate proteoglycan catabolic process+++GO:0030201///heparan sulfate proteoglycan metabolic process 27041 27041 'G3bp1' mRNA 2507 2652 2656 51.35 53.56 57.66 69.26 70.57 66.98 54.19 68.93666667 3875 3860 3625 2605 3786.666667 4.41E-14 0.526470027 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0043204///perikaryon+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003729///mRNA binding+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0033677///DNA/RNA helicase activity GO:0002376///immune system process+++GO:0032481///positive regulation of type I interferon production+++GO:0032508///DNA duplex unwinding+++GO:0034063///stress granule assembly+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0062029///positive regulation of stress granule assembly+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 27045 27045 'Nit1' mRNA 906.84 957.5 874.08 32.95 34.86 33.41 32.37 31.15 32.9 33.74 32.14 988.82 893.68 970.37 912.8066667 950.9566667 0.696837118 0.047345129 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0050406///[acetyl-CoA carboxylase]-phosphatase activity+++GO:0110050///deaminated glutathione amidase activity GO:0006470///protein dephosphorylation+++GO:0006807///nitrogen compound metabolic process+++GO:0043605///cellular amide catabolic process 27047 27047 'Omd' mRNA 130.22 150.4 130.65 3.68 4.16 3.89 6.03 6.25 6.83 3.91 6.37 245.87 250.01 269.95 137.09 255.2766667 8.56E-07 0.887970284 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0007155///cell adhesion+++GO:0030500///regulation of bone mineralization 27049 27049 'Etv3' mRNA 500.1 454 360 5.19 4.63 3.96 5.05 4.57 5.03 4.593333333 4.883333333 560 495 541 438.0333333 532 0.049931509 0.272729405 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090571///RNA polymerase II transcription repressor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus" 27050 27050 'Rps3' mRNA 6842 6578 6268 208.79 197.8 202.91 253.69 232.83 243.75 203.1666667 243.4233333 9556 8561 8886 6562.666667 9001 2.29E-16 0.443721739 03010///Ribosome+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0032587///ruffle membrane+++GO:0045202///synapse+++GO:0071159///NF-kappaB complex+++GO:0072686///mitotic spindle+++GO:1990904///ribonucleoprotein complex GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008134///transcription factor binding+++GO:0015631///tubulin binding+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0032357///oxidized purine DNA binding+++GO:0032358///oxidized pyrimidine DNA binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0051018///protein kinase A binding+++GO:0051879///Hsp90 protein binding+++GO:0070181///small ribosomal subunit rRNA binding+++GO:0097100///supercoiled DNA binding+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity "GO:0006281///DNA repair+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0010628///positive regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032079///positive regulation of endodeoxyribonuclease activity+++GO:0032743///positive regulation of interleukin-2 production+++GO:0034614///cellular response to reactive oxygen species+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045738///negative regulation of DNA repair+++GO:0045739///positive regulation of DNA repair+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0061481///response to TNF agonist+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1902546///positive regulation of DNA N-glycosylase activity+++GO:1905053///positive regulation of base-excision repair+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001272///positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis" 27052 27052 'Aoah' mRNA 37 47 27 0.84 1.05 0.54 12.65 10.31 12.38 0.81 11.78 609 482 597 37 562.6666667 6.92E-84 3.917767276 GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle "GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding+++GO:0050528///acyloxyacyl hydrolase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0008653///lipopolysaccharide metabolic process+++GO:0009104///lipopolysaccharide catabolic process+++GO:0050728///negative regulation of inflammatory response 27053 27053 'Asns' mRNA 571 592 634 16.62 16.98 19.58 14.24 14.37 13.41 17.72666667 14.00666667 561 550 512 599 541 0.231282527 -0.161452625 "00250///Alanine, aspartate and glutamate metabolism+++01230///Biosynthesis of amino acids" GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004066///asparagine synthase (glutamine-hydrolyzing) activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0001889///liver development+++GO:0006520///cellular amino acid metabolic process+++GO:0006529///asparagine biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009416///response to light stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009636///response to toxic substance+++GO:0031427///response to methotrexate+++GO:0031667///response to nutrient levels+++GO:0032354///response to follicle-stimulating hormone+++GO:0032870///cellular response to hormone stimulus+++GO:0042149///cellular response to glucose starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0043200///response to amino acid+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0070981///L-asparagine biosynthetic process 27054 27054 'Sec23b' mRNA 2011 2111 2122 39.54 40.91 44.3 44.94 44.39 43.96 41.58333333 44.43 2630 2542 2491 2081.333333 2554.333333 1.45E-04 0.282079989 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding 27055 27055 'Fkbp9' mRNA 7925 8183 7779 144.54 146.87 150.5 126.56 123.09 126.74 147.3033333 125.4633333 7984 7584 7742 7962.333333 7770 0.454658801 -0.047348492 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005509///calcium ion binding+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 27056 27056 'Irf5' mRNA 141.48 127.75 133.65 2.92 2.67 2.93 34.24 36.35 33.77 2.84 34.78666667 1564.81 1625.09 1508.25 134.2933333 1566.05 6.06E-210 3.538858818 04620///Toll-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032481///positive regulation of type I interferon production+++GO:0032494///response to peptidoglycan+++GO:0032495///response to muramyl dipeptide+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus" 27057 27057 'Ncoa4' mRNA 2709 2957 2772 42.84 46 46.44 74.05 71.57 69.88 45.09333333 71.83333333 5385 5081 4911 2812.666667 5125.666667 1.03E-42 0.853463964 04216///Ferroptosis+++05200///Pathways in cancer+++05216///Thyroid cancer GO:0005739///mitochondrion+++GO:0044754///autolysosome GO:0003674///molecular_function+++GO:0003713///transcription coactivator activity "GO:0006622///protein targeting to lysosome+++GO:0006879///cellular iron ion homeostasis+++GO:0009725///response to hormone+++GO:0045893///positive regulation of transcription, DNA-templated" 27058 27058 'Srp9' mRNA 1726 1776 1692 74.39 75.53 77.37 91.95 94.64 89.98 75.76333333 92.19 2450 2460 2319 1731.333333 2409.666667 2.71E-11 0.465376071 03060///Protein export "GO:0005737///cytoplasm+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0048500///signal recognition particle" GO:0003723///RNA binding+++GO:0008312///7S RNA binding GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0045900///negative regulation of translational elongation 27059 27059 'Sh3d19' mRNA 743 723 539 8.8 8.93 5.09 9.21 9.95 9.8 7.606666667 9.653333333 1053 1009 1015 668.3333333 1025.666667 1.26E-08 0.611542542 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0070064///proline-rich region binding GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis 270599 270599 'Gm648' mRNA 1 0 1 0.07 0 0.08 0 0 0 0.05 0 0 0 0 0.666666667 0 0.746936975 -1.892661915 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 27060 27060 'Tcirg1' mRNA 1022 956 1003 20.87 19.31 21.83 75.6 72.51 78.02 20.67 75.37666667 4262 3975 4242 993.6666667 4159.666667 3.66E-185 2.052465007 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030667///secretory granule membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0045335///phagocytic vesicle" "GO:0005515///protein binding+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0000045///autophagosome assembly+++GO:0001503///ossification+++GO:0002158///osteoclast proliferation+++GO:0002377///immunoglobulin production+++GO:0006811///ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007035///vacuolar acidification+++GO:0007039///protein catabolic process in the vacuole+++GO:0010155///regulation of proton transport+++GO:0010272///response to silver ion+++GO:0010467///gene expression+++GO:0010468///regulation of gene expression+++GO:0016064///immunoglobulin mediated immune response+++GO:0016236///macroautophagy+++GO:0021554///optic nerve development+++GO:0030010///establishment of cell polarity+++GO:0030099///myeloid cell differentiation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0030316///osteoclast differentiation+++GO:0031529///ruffle organization+++GO:0032609///interferon-gamma production+++GO:0033365///protein localization to organelle+++GO:0035709///memory T cell activation+++GO:0035711///T-helper 1 cell activation+++GO:0042476///odontogenesis+++GO:0043029///T cell homeostasis+++GO:0044691///tooth eruption+++GO:0045453///bone resorption+++GO:0045667///regulation of osteoblast differentiation+++GO:0045851///pH reduction+++GO:0048872///homeostasis of number of cells+++GO:0050796///regulation of insulin secretion+++GO:0051452///intracellular pH reduction+++GO:0051650///establishment of vesicle localization+++GO:0060041///retina development in camera-type eye+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0070166///enamel mineralization+++GO:0071345///cellular response to cytokine stimulus+++GO:0090383///phagosome acidification+++GO:0097188///dentin mineralization+++GO:1902600///proton transmembrane transport 27061 27061 'Bcap31' mRNA 3708.04 3810.1 3896 180.24 182.79 200.73 229.58 240.93 238.89 187.92 236.4666667 5402.2 5540 5443.06 3804.713333 5461.753333 1.16E-14 0.508481416 04141///Protein processing in endoplasmic reticulum+++05165///Human papillomavirus infection GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0097038///perinuclear endoplasmic reticulum GO:0005515///protein binding+++GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding "GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 27062 27062 'Cadps' mRNA 14 10 11 0.13 0.1 0.11 0.01 0 0 0.113333333 0.003333333 1 0 0 11.66666667 0.333333333 0.001418027 -5.036839269 GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0098674///extrinsic component of neuronal dense core vesicle membrane+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099012///neuronal dense core vesicle membrane "GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding" GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0016050///vesicle organization+++GO:0016079///synaptic vesicle exocytosis+++GO:0016082///synaptic vesicle priming+++GO:0045921///positive regulation of exocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0050432///catecholamine secretion+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:1990504///dense core granule exocytosis 270624 270624 'Spin4' mRNA 55 58 80 0.71 0.74 1.09 0.77 0.64 0.76 0.846666667 0.723333333 69 56 66 64.33333333 63.66666667 0.933666469 -0.036272019 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 270627 270627 'Taf1' mRNA 1089.13 1102.7 990.89 7.83 7.83 7.55 5.48 5.28 5.79 7.736666667 5.516666667 875.26 823.62 891.91 1060.906667 863.5966667 6.70E-04 -0.307577047 03022///Basal transcription factors GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005669///transcription factor TFIID complex+++GO:0005730///nucleolus+++GO:0045120///pronucleus+++GO:0071339///MLL1 complex "GO:0000166///nucleotide binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0004402///histone acetyltransferase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016922///nuclear receptor binding+++GO:0017025///TBP-class protein binding+++GO:0035257///nuclear hormone receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0061628///H3K27me3 modified histone binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0070577///lysine-acetylated histone binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0006352///DNA-templated transcription, initiation+++GO:0006360///transcription by RNA polymerase I+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006468///protein phosphorylation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0016573///histone acetylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030901///midbrain development+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034644///cellular response to UV+++GO:0036369///transcription factor catabolic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0071318///cellular response to ATP+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1905524///negative regulation of protein autoubiquitination+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000825///positive regulation of androgen receptor activity" 270669 270669 'Mbtps2' mRNA 554 497 368 6.18 5.45 4.35 4.38 4.1 4.57 5.326666667 4.35 452 414 457 473 441 0.547668264 -0.106806722 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031519///PcG protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070977///bone maturation+++GO:1905897///regulation of response to endoplasmic reticulum stress+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 270672 270672 'Map3k15' mRNA 2.1 6.3 9.43 0.02 0.07 0.12 0.31 0.12 0.19 0.07 0.206666667 30.35 11.6 17.86 5.943333333 19.93666667 0.037550714 1.736455301 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0033554///cellular response to stress 270685 270685 'Mthfd1l' mRNA 131 140 103 3.16 3.45 2.47 4.93 4.09 4.7 3.026666667 4.573333333 309 265 314 124.6666667 296 4.94E-12 1.239371855 00670///One carbon pool by folate+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042803///protein homodimerization activity GO:0001843///neural tube closure+++GO:0006730///one-carbon metabolic process+++GO:0006760///folic acid-containing compound metabolic process+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0015942///formate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis 270757 270757 'Bpifc' mRNA 19 35 25 0.46 0.83 0.64 0.48 0.34 0.43 0.643333333 0.416666667 23 16 20 26.33333333 19.66666667 0.49484972 -0.432691169 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0008289///lipid binding GO:0008150///biological_process 27078 27078 'B9d1' mRNA 749 717 594 62.39 58.82 52.09 34.78 35.95 33.24 57.76666667 34.65666667 475 480 445 686.6666667 466.6666667 9.43E-07 -0.565231456 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0008158///hedgehog receptor activity GO:0001701///in utero embryonic development+++GO:0001944///vasculature development+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0032880///regulation of protein localization+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0060271///cilium assembly+++GO:0060563///neuroepithelial cell differentiation 270802 270802 'BC048403' mRNA 89 73 54 1.58 1.26 1.01 1.62 1.56 1.6 1.283333333 1.593333333 106 99 101 72 102 0.094320289 0.496600074 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0045171///intercellular bridge+++GO:0140007///KICSTOR complex GO:0003674///molecular_function GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0061462///protein localization to lysosome+++GO:1904262///negative regulation of TORC1 signaling 27081 27081 'Zfp275' mRNA 475 476 458 4 3.95 4.1 3.65 3.21 3.69 4.016666667 3.516666667 497 429 487 469.6666667 471 0.961585389 -0.008428055 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 27083 27083 'Xlr4b' mRNA 10.25 15.65 16.29 0.52 0.76 0.83 2.35 2.7 1.87 0.703333333 2.306666667 54.98 62.17 41.28 14.06333333 52.81 4.03E-05 1.922784173 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis 27084 27084 'Xlr5c' mRNA 0 0 1 0 0 0.16 0 0 0 0.053333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 270893 270893 'Tmem132e' mRNA 6 2 0 0.07 0.02 0 0.01 0 0.05 0.03 0.02 1 0 5 2.666666667 2 0.865996977 -0.397591681 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0044297///cell body GO:0003674///molecular_function GO:0035677///posterior lateral line neuromast hair cell development 270906 270906 'Prr11' mRNA 68.06 80.62 66.59 0.96 1.12 1 2.47 2.13 1.8 1.026666667 2.133333333 200.93 169.75 142.15 71.75666667 170.9433333 1.78E-07 1.24410788 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007050///cell cycle arrest+++GO:0051726///regulation of cell cycle 27096 27096 'Trappc3' mRNA 2194 2104 2033 106.35 100.69 104.56 108.53 106.64 106.11 103.8666667 107.0933333 2570 2463 2430 2110.333333 2487.666667 0.001036751 0.225621944 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030008///TRAPP complex+++GO:0033106///cis-Golgi network membrane GO:0005515///protein binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048193///Golgi vesicle transport 271005 271005 'Klhdc1' mRNA 443 496 516 9.84 11.07 12.57 3.23 3.2 3.34 11.16 3.256666667 173 171 174 485 172.6666667 5.22E-24 -1.504414556 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031466///Cul5-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0008150///biological_process+++GO:0016567///protein ubiquitination 27103 27103 'Eif2ak4' mRNA 496 562 508 5.04 5.65 5.5 4.89 5.23 4.83 5.396666667 4.983333333 554 575 527 522 552 0.646301219 0.06973567 04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++05160///Hepatitis C+++05162///Measles+++05168///Herpes simplex virus 1 infection GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0022626///cytosolic ribosome GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0071074///eukaryotic initiation factor eIF2 binding GO:0000077///DNA damage checkpoint+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002821///positive regulation of adaptive immune response+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007399///nervous system development+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0009267///cellular response to starvation+++GO:0010628///positive regulation of gene expression+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0019081///viral translation+++GO:0030154///cell differentiation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032057///negative regulation of translational initiation in response to stress+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0034198///cellular response to amino acid starvation+++GO:0034644///cellular response to UV+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036492///eiF2alpha phosphorylation in response to endoplasmic reticulum stress+++GO:0039520///induction by virus of host autophagy+++GO:0043558///regulation of translational initiation in response to stress+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045665///negative regulation of neuron differentiation+++GO:0045947///negative regulation of translational initiation+++GO:0046777///protein autophosphorylation+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0060259///regulation of feeding behavior+++GO:0070417///cellular response to cold+++GO:0071264///positive regulation of translational initiation in response to starvation+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1990138///neuron projection extension+++GO:1990253///cellular response to leucine starvation 271047 271047 'Serpina3b' mRNA 0 0 2 0 0 0.09 0 0 0 0.03 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 271127 271127 'Adamts16' mRNA 13 10 20 0.15 0.11 0.23 0.06 0.11 0.06 0.163333333 0.076666667 6 11 3 14.33333333 6.666666667 0.212304924 -1.126738786 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization+++GO:0048232///male gamete generation+++GO:1902017///regulation of cilium assembly 271144 271144 'Ankdd1b' mRNA 6.06 6.49 7.87 0.1 0.11 0.14 0.13 0.12 0.04 0.116666667 0.096666667 9.32 7.92 2 6.806666667 6.413333333 0.942475093 -0.097838462 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008150///biological_process 271221 271221 'Rubcnl' mRNA 52 46 44 1.25 1.22 1.09 2.42 2.21 2.32 1.186666667 2.316666667 120 109 113 47.33333333 114 5.49E-06 1.256894776 GO:0000421///autophagosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0006629///lipid metabolic process+++GO:0006914///autophagy+++GO:0019216///regulation of lipid metabolic process+++GO:0061909///autophagosome-lysosome fusion+++GO:0061910///autophagosome-endosome fusion+++GO:0070873///regulation of glycogen metabolic process+++GO:0097352///autophagosome maturation 271278 271278 'BC024139' mRNA 20.14 13.09 19.16 0.42 0.27 0.43 0.22 0.35 0.38 0.373333333 0.316666667 12.23 18.45 20 17.46333333 16.89333333 0.931252587 -0.069528954 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005882///intermediate filament+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0005198///structural molecule activity+++GO:0008017///microtubule binding GO:0032886///regulation of microtubule-based process+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0051893///regulation of focal adhesion assembly 271305 271305 'Phf21b' mRNA 58 44 48 0.99 0.7 0.82 1 0.55 0.69 0.836666667 0.746666667 66 37 47 50 50 0.978250253 -0.016504154 GO:0046872///metal ion binding 271377 271377 'Zbtb11' mRNA 948 982 769 8.4 8.39 8 5.07 5.98 6.48 8.263333333 5.843333333 604 735 756 899.6666667 698.3333333 0.002560218 -0.370702073 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated" 27140 27140 'Tlx3' mRNA 1 3 0 0.01 0.03 0 0 0 0 0.013333333 0 0 0 0 1.333333333 0 0.492448657 -2.82872934 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001708///cell fate specification+++GO:0001764///neuron migration+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0007585///respiratory gaseous exchange+++GO:0030182///neuron differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0048513///animal organ development+++GO:0048665///neuron fate specification" 271424 271424 'Ip6k3' mRNA 38 36 35 0.93 0.86 0.9 1.82 1.71 1.66 0.896666667 1.73 86 79 76 36.33333333 80.33333333 5.25E-04 1.132738016 04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0000831///inositol hexakisphosphate 6-kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity" GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0040011///locomotion+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation 271457 271457 'Rab5a' mRNA 1123.56 1305.51 435.62 26.61 30.45 10.94 17.52 19.8 23.65 22.66666667 20.32333333 850.67 938.59 1111.65 954.8966667 966.97 0.964732391 0.029845262 04014///Ras signaling pathway+++04144///Endocytosis+++04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection+++05146///Amoebiasis+++05152///Tuberculosis GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032009///early phagosome+++GO:0032991///protein-containing complex+++GO:0036477///somatodendritic compartment+++GO:0042470///melanosome+++GO:0042589///zymogen granule membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0045121///membrane raft+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0098559///cytoplasmic side of early endosome membrane+++GO:0098842///postsynaptic early endosome+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019001///guanyl nucleotide binding+++GO:0019003///GDP binding+++GO:0051021///GDP-dissociation inhibitor binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006909///phagocytosis+++GO:0007032///endosome organization+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0015031///protein transport+++GO:0030100///regulation of endocytosis+++GO:0036465///synaptic vesicle recycling+++GO:0039694///viral RNA genome replication+++GO:0045022///early endosome to late endosome transport+++GO:0045921///positive regulation of exocytosis+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051036///regulation of endosome size+++GO:0051489///regulation of filopodium assembly+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:2000300///regulation of synaptic vesicle exocytosis 271508 271508 'Brd8dc' mRNA 25 21 26 0.59 0.5 0.68 0.33 0.23 0.32 0.59 0.293333333 15 11 14 24 13.33333333 0.164394518 -0.865336 GO:0035267///NuA4 histone acetyltransferase complex GO:0003674///molecular_function GO:0016573///histone acetylation 271564 271564 'Vps13a' mRNA 594 514 503 2.71 2.36 2.5 2.64 2.15 2.48 2.523333333 2.423333333 653 526 603 537 594 0.349863462 0.133126569 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0097225///sperm midpiece+++GO:0098992///neuronal dense core vesicle+++GO:0099013///neuronal dense core vesicle lumen GO:0003674///molecular_function GO:0006623///protein targeting to vacuole+++GO:0006914///autophagy+++GO:0007399///nervous system development+++GO:0007626///locomotory behavior+++GO:0015031///protein transport+++GO:0030317///flagellated sperm motility+++GO:0030382///sperm mitochondrion organization+++GO:0035176///social behavior+++GO:0045053///protein retention in Golgi apparatus+++GO:1905146///lysosomal protein catabolic process 271639 271639 'Adcy10' mRNA 22 18 13 0.13 0.12 0.08 0.09 0.06 0.05 0.11 0.066666667 17 10 8 17.66666667 11.66666667 0.435235137 -0.608307932 "00230///Purine metabolism+++04024///cAMP signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04714///Thermogenesis+++04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell+++GO:0045178///basal part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004016///adenylate cyclase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding+++GO:0071890///bicarbonate binding GO:0003351///epithelial cilium movement+++GO:0006171///cAMP biosynthetic process+++GO:0007283///spermatogenesis+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0071241///cellular response to inorganic substance 271697 271697 'Cdk15' mRNA 388 404 343 14.53 14.71 13.32 3.09 3.03 3.87 14.18666667 3.33 97 93 118 378.3333333 102.6666667 1.55E-28 -1.890743288 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0046872///metal ion binding GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle 271711 271711 'Tmem169' mRNA 14 22 28 0.26 0.41 0.53 0.07 0.07 0.07 0.4 0.07 4 4 4 21.33333333 4 0.001928559 -2.437068484 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 27176 27176 'Rpl7a' mRNA 2741.73 2652.1 2381.25 208.96 200.6 193.29 304.24 279.92 315.96 200.95 300.04 4569.17 4093.94 4574.2 2591.693333 4412.436667 2.27E-32 0.757215075 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0000470///maturation of LSU-rRNA+++GO:0042254///ribosome biogenesis 271786 271786 'Galnt13' mRNA 78 92 57 1.12 1.28 0.67 0.03 0.02 0.13 1.023333333 0.06 4 4 14 75.66666667 7.333333333 2.32E-11 -3.368829868 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine 271813 271813 'Agbl2' mRNA 441 481 433 6.82 7.46 7.18 1.3 1.85 1.96 7.153333333 1.703333333 98 134 138 451.6666667 123.3333333 2.56E-29 -1.881290639 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0035610///protein side chain deglutamylation 271842 271842 'Rpusd2' mRNA 119 130 79 1.24 1.33 0.87 0.97 0.76 0.86 1.146666667 0.863333333 108 82 92 109.3333333 94 0.485662493 -0.223259941 GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0009451///RNA modification+++GO:1990481///mRNA pseudouridine synthesis 271844 271844 'Pla2g4f' mRNA 0 2 2 0 0.03 0.04 0.14 0.06 0.02 0.023333333 0.073333333 9 3 1 1.333333333 4.333333333 0.379519187 1.665154511 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04217///Necroptosis+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0032587///ruffle membrane "GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0015908///fatty acid transport+++GO:0016042///lipid catabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0050482///arachidonic acid secretion+++GO:0071236///cellular response to antibiotic+++GO:0071407///cellular response to organic cyclic compound 271849 271849 'Shc4' mRNA 955 1020 706 11.55 12.25 9.78 6.64 8.39 7.5 11.19333333 7.51 548 735 634 893.6666667 639 5.23E-04 -0.485794253 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04722///Neurotrophin signaling pathway+++04910///Insulin signaling pathway+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05034///Alcoholism+++05100///Bacterial invasion of epithelial cells+++05206///MicroRNAs in cancer+++05214///Glioma+++05220///Chronic myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer" GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030971///receptor tyrosine kinase binding GO:0006915///apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0035556///intracellular signal transduction+++GO:0048863///stem cell differentiation 271887 271887 'Rbbp8nl' mRNA 126 143 99 2.35 2.46 1.84 0.61 0.79 1.1 2.216666667 0.833333333 40 51 69 122.6666667 53.33333333 4.39E-05 -1.204789291 GO:0003674///molecular_function GO:0008150///biological_process 271944 271944 'C2cd4d' mRNA 20 24 4 0.92 1.09 0.19 0.28 0.16 0.17 0.733333333 0.203333333 7 4 4 16 5 0.073274598 -1.667977536 GO:0008150///biological_process 271970 271970 'Arsj' mRNA 29 34 39 0.43 0.49 0.61 0.09 0.09 0.32 0.51 0.166666667 7 7 24 34 12.66666667 0.020004943 -1.439320705 GO:0005576///extracellular region+++GO:0015629///actin cytoskeleton GO:0003824///catalytic activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding 271981 271981 'Tbck' mRNA 1180.54 1138.02 1111.72 9.64 9.13 9.68 9.1 8.66 8.35 9.483333333 8.703333333 1274.62 1198.74 1143.19 1143.426667 1205.516667 0.546801296 0.064008192 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0072686///mitotic spindle GO:0004672///protein kinase activity+++GO:0005096///GTPase activator activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0006886///intracellular protein transport+++GO:0008283///cell proliferation+++GO:0030036///actin cytoskeleton organization+++GO:0032006///regulation of TOR signaling+++GO:0090630///activation of GTPase activity 272009 272009 'Srsf12' mRNA 90 100 110 1.73 1.9 2.24 0.97 0.88 1.22 1.956666667 1.023333333 58 51 71 100 60 0.011646965 -0.752643371 GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0003723///RNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000395///mRNA 5'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 272027 272027 'Tstd2' mRNA 591.98 597.74 533.62 8.47 8.41 8.12 8.1 7.43 8.85 8.333333333 8.126666667 651.05 580.14 687.31 574.4466667 639.5 0.250717656 0.145703122 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 272031 272031 'Plppr1' mRNA 6 4 1 0.09 0.03 0.02 0 0 0 0.046666667 0 0 0 0 3.666666667 0 0.064832041 -4.305254212 GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008195///phosphatidate phosphatase activity+++GO:0042577///lipid phosphatase activity GO:0006644///phospholipid metabolic process+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0046839///phospholipid dephosphorylation 27204 27204 'Syn3' mRNA 1945.16 2020.49 1745.89 6.49 7.01 6.51 2.57 1.93 2.1 6.67 2.2 941.97 742.63 806.73 1903.846667 830.4433333 2.08E-43 -1.209306744 GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005524///ATP binding GO:0007269///neurotransmitter secretion+++GO:0097091///synaptic vesicle clustering+++GO:0099504///synaptic vesicle cycle 27205 27205 'Podxl' mRNA 1436 1353 1072 14.36 13.3 11.37 14.84 15.35 16 13.01 15.39666667 1709 1727 1785 1287 1740.333333 2.89E-06 0.428815351 05132///Salmonella infection GO:0001726///ruffle+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031528///microvillus membrane+++GO:0034451///centriolar satellite+++GO:0036057///slit diaphragm+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0016477///cell migration+++GO:0022407///regulation of cell-cell adhesion+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:0032534///regulation of microvillus assembly+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0050900///leukocyte migration+++GO:0072015///glomerular visceral epithelial cell development+++GO:0072175///epithelial tube formation 27207 27207 'Rps11' mRNA 2842.11 3017 2827 360.39 380.93 380.52 588.77 611.61 642.2 373.9466667 614.1933333 5297 5348 5568 2895.37 5404.333333 6.83E-49 0.8891963 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0006412///translation 27214 27214 'Dbf4' mRNA 27 21 13 0.62 0.47 0.32 1.83 2.24 2.38 0.47 2.15 92 110 116 20.33333333 106 1.17E-11 2.379371392 04110///Cell cycle GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031431///Dbf4-dependent protein kinase complex GO:0003676///nucleic acid binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008270///zinc ion binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901987///regulation of cell cycle phase transition 27215 27215 'Azi2' mRNA 1383.48 1435.26 1385.36 23.16 24.98 25.43 26.15 25.64 27.27 24.52333333 26.35333333 1663.73 1507.76 1576.03 1401.366667 1582.506667 0.051222758 0.16258566 04622///RIG-I-like receptor signaling pathway GO:0005737///cytoplasm GO:0005515///protein binding GO:0000278///mitotic cell cycle+++GO:0001816///cytokine production+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0032607///interferon-alpha production+++GO:0032609///interferon-gamma production+++GO:0032635///interleukin-6 production+++GO:0032640///tumor necrosis factor production+++GO:0042110///T cell activation+++GO:0044565///dendritic cell proliferation+++GO:0097028///dendritic cell differentiation 272158 272158 'Poln' mRNA 68 53 47 1.26 0.98 0.94 1.06 1.1 1.18 1.06 1.113333333 66 67 70 56 67.66666667 0.488376604 0.265138622 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0030332///cyclin binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019985///translesion synthesis+++GO:0036297///interstrand cross-link repair+++GO:0071897///DNA biosynthetic process 27218 27218 'Slamf1' mRNA 1 2 4 0.05 0.1 0.14 0.62 0.29 0.23 0.096666667 0.38 15 12 9 2.333333333 12 0.028667948 2.334676398 05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045335///phagocytic vesicle GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding GO:0001779///natural killer cell differentiation+++GO:0001787///natural killer cell proliferation+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002250///adaptive immune response+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002725///negative regulation of T cell cytokine production+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0031338///regulation of vesicle fusion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0046649///lymphocyte activation+++GO:0050790///regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000349///negative regulation of CD40 signaling pathway+++GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:2000556///positive regulation of T-helper 1 cell cytokine production 27219 27219 'Sgk2' mRNA 2 0 0 0.05 0 0 0.02 0.04 0.02 0.016666667 0.026666667 1 2 1 0.666666667 1.333333333 0.766483962 1.013145471 04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0015459///potassium channel regulator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 27220 27220 'Cartpt' mRNA 84 91 69 6.63 7.16 5.72 0.2 0.5 0.64 6.503333333 0.446666667 3 7 9 81.33333333 6.333333333 2.30E-14 -3.687277257 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule+++GO:0045202///synapse GO:0005184///neuropeptide hormone activity GO:0000186///activation of MAPKK activity+++GO:0001678///cellular glucose homeostasis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0008343///adult feeding behavior+++GO:0009267///cellular response to starvation+++GO:0032099///negative regulation of appetite+++GO:0032812///positive regulation of epinephrine secretion+++GO:0032922///circadian regulation of gene expression+++GO:0043410///positive regulation of MAPK cascade+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045777///positive regulation of blood pressure+++GO:0045779///negative regulation of bone resorption+++GO:0045860///positive regulation of protein kinase activity+++GO:0046850///regulation of bone remodeling+++GO:0050796///regulation of insulin secretion+++GO:0051971///positive regulation of transmission of nerve impulse+++GO:0070093///negative regulation of glucagon secretion+++GO:0070253///somatostatin secretion 27221 27221 'Chaf1a' mRNA 73.15 56.61 59.09 1.21 0.92 1.03 4.73 4.19 4.79 1.053333333 4.57 330.18 285.81 323.66 62.95 313.2166667 2.44E-31 2.306794804 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0033186///CAF-1 complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0070087///chromo shadow domain binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031497///chromatin assembly 27222 27222 'Atp1a4' mRNA 9 14 9 0.2 0.21 0.21 0.16 0.15 0.06 0.206666667 0.123333333 12 7.91 3 10.66666667 7.636666667 0.606577914 -0.553141465 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097225///sperm midpiece+++GO:0097733///photoreceptor cell cilium GO:0000166///nucleotide binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0030007///cellular potassium ion homeostasis+++GO:0030317///flagellated sperm motility+++GO:0030641///regulation of cellular pH+++GO:0035725///sodium ion transmembrane transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0042391///regulation of membrane potential+++GO:0071805///potassium ion transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 27223 27223 'Trp53bp1' mRNA 1387.78 1556.66 1355.85 9.13 9.96 9.18 5.34 4.67 5.99 9.423333333 5.333333333 885.98 763.58 926.55 1433.43 858.7033333 6.26E-16 -0.750754813 04621///NOD-like receptor signaling pathway "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0035861///site of double-strand break+++GO:1990391///DNA repair complex" GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0035064///methylated histone binding+++GO:0042162///telomeric DNA binding+++GO:0042393///histone binding+++GO:0043565///sequence-specific DNA binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061649///ubiquitin modification-dependent histone binding "GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045830///positive regulation of isotype switching+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051260///protein homooligomerization+++GO:0071481///cellular response to X-ray+++GO:2000042///negative regulation of double-strand break repair via homologous recombination" 27224 27224 'Eloa' mRNA 1466 1603 1544 17.12 18.41 19.12 26.75 24.32 25.74 18.21666667 25.60333333 2637 2342 2458 1537.666667 2479 1.87E-19 0.675676274 GO:0005634///nucleus+++GO:0008023///transcription elongation factor complex+++GO:0070449///elongin complex+++GO:0090734///site of DNA damage GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter 27225 27225 'Ddx24' mRNA 2695 2849 2821 51.06 53.03 56.84 50.73 51.87 50.66 53.64333333 51.08666667 3084 3077 2978 2788.333333 3046.333333 0.133475093 0.114855255 GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 27226 27226 'Pla2g7' mRNA 15445 15855 15582 459.19 464.35 492.29 380.8 410.05 382.77 471.9433333 391.2066667 14719 15452 14300 15627.33333 14823.66667 0.183964721 -0.088238581 00565///Ether lipid metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0034362///low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0005543///phospholipid binding+++GO:0016787///hydrolase activity+++GO:0047499///calcium-independent phospholipase A2 activity GO:0006629///lipid metabolic process+++GO:0006954///inflammatory response+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0034440///lipid oxidation+++GO:0034441///plasma lipoprotein particle oxidation+++GO:0034638///phosphatidylcholine catabolic process+++GO:0046469///platelet activating factor metabolic process+++GO:0090026///positive regulation of monocyte chemotaxis 272322 272322 'Arntl2' mRNA 117 89 98 2.61 1.93 2.19 1.27 1.83 1.48 2.243333333 1.526666667 67 97 76 101.3333333 80 0.267372796 -0.350327054 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0034751///aryl hydrocarbon receptor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0042753///positive regulation of circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process" 272347 272347 'Zfp398' mRNA 941.73 1031.64 892.05 7.99 8.76 7.94 5.38 5 5.25 8.23 5.21 756.8 657.96 687.81 955.14 700.8566667 2.37E-06 -0.458702189 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 272359 272359 'Irf2bp1' mRNA 384 352 332 7.86 7.09 7.2 5.69 6.37 6.08 7.383333333 6.046666667 320 350 331 356 333.6666667 0.556033338 -0.103170537 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003714///transcription corepressor activity+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0006357///regulation of transcription by RNA polymerase II 272381 272381 'Lrrc4b' mRNA 24 29 26 0.49 0.58 0.56 0.21 0.31 0.16 0.543333333 0.226666667 12 17 9 26.33333333 12.66666667 0.079309195 -1.065346344 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0044300///cerebellar mossy fiber+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0051965///positive regulation of synapse assembly+++GO:0099151///regulation of postsynaptic density assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 272382 272382 'Spib' mRNA 5 1 0 0.08 0.02 0 0.27 0.25 0.65 0.033333333 0.39 15.51 14 37.99 2 22.5 5.03E-04 3.463536055 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002327///immature B cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030225///macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 272396 272396 'Tarsl2' mRNA 281 287 92 4.81 4.84 1.67 0.83 1.49 2.41 3.773333333 1.576666667 56 98 157 220 103.6666667 0.133269526 -1.068616962 00970///Aminoacyl-tRNA biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004829///threonine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006435///threonyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation 272411 272411 'B3gnt6' mRNA 1 2 5 0.02 0.05 0.13 0.02 0 0.11 0.066666667 0.043333333 1 0 5 2.666666667 2 0.859557176 -0.454022374 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047224///acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 272465 272465 'Tmem255b' mRNA 6167.8 6136.01 5839.78 170.3 168.08 173.39 24.02 21.98 25.39 170.59 23.79666667 918.97 783.02 900.01 6047.863333 867.3333333 0 -2.814574483 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 272538 272538 'Tango6' mRNA 718 699 677 8.75 8.38 8.75 3.55 3.58 3.68 8.626666667 3.603333333 335 330 337 698 334 1.13E-21 -1.074938905 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009306///protein secretion 272551 272551 'Gins2' mRNA 52 56 56 3.17 3.38 3.63 13.41 14.2 10.78 3.393333333 12.79666667 252 260 195.77 54.66666667 235.9233333 2.42E-20 2.095600668 GO:0000811///GINS complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0071162///CMG complex GO:0000727///double-strand break repair via break-induced replication+++GO:0006260///DNA replication 272589 272589 'Tbcel' mRNA 455 450 432 5.01 4.87 5.04 3.7 3.32 3.36 4.973333333 3.46 387 338 340 445.6666667 355 0.011063832 -0.340666833 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0043014///alpha-tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007023///post-chaperonin tubulin folding pathway 27260 27260 'Plek2' mRNA 17 11 11 0.64 0.41 0.44 1.55 1.42 1.64 0.496666667 1.536666667 47 42 48 13 45.66666667 1.80E-04 1.802689373 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection "GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0030036///actin cytoskeleton organization+++GO:0031346///positive regulation of cell projection organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction+++GO:0120034///positive regulation of plasma membrane bounded cell projection assembly 27261 27261 'Dok3' mRNA 208 207 172 5.36 5.93 5.12 28.32 28.04 26.19 5.47 27.51666667 880 839 789 195.6666667 836 5.25E-67 2.085572878 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction 27263 27263 'Smok2a' mRNA 56.47 49.91 43.07 1.82 1.59 1.47 0.56 0.68 0.64 1.626666667 0.626666667 20.1 23.63 22.21 49.81666667 21.98 0.005139021 -1.19476924 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 272636 272636 'Esyt3' mRNA 132.28 113.03 78.84 1.64 1.44 1.06 1.48 1.3 1.42 1.38 1.4 129.14 115.21 129.46 108.05 124.6033333 0.500988432 0.202753297 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0044232///organelle membrane contact site GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0061817///endoplasmic reticulum-plasma membrane tethering 272643 272643 'Prss43' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 27267 27267 'Cars' mRNA 938 1068 1042 19.48 22.45 22.55 18.82 20.68 18.28 21.49333333 19.26 1041 1088 947 1016 1025.333333 0.998591786 4.34E-04 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004817///cysteine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006423///cysteinyl-tRNA aminoacylation 27273 27273 'Pdk4' mRNA 1230 1324 1400 19.39 20.53 23.41 24.27 19.5 20.61 21.11 21.46 1772 1391 1457 1318 1540 0.061756738 0.207580984 05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004740///pyruvate dehydrogenase (acetyl-transferring) kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006468///protein phosphorylation+++GO:0006885///regulation of pH+++GO:0008286///insulin receptor signaling pathway+++GO:0009267///cellular response to starvation+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate+++GO:0010565///regulation of cellular ketone metabolic process+++GO:0010906///regulation of glucose metabolic process+++GO:0016310///phosphorylation+++GO:0042304///regulation of fatty acid biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0042594///response to starvation+++GO:0045124///regulation of bone resorption+++GO:0046320///regulation of fatty acid oxidation+++GO:0071398///cellular response to fatty acid+++GO:0072593///reactive oxygen species metabolic process+++GO:2000811///negative regulation of anoikis 27274 27274 'Zfp354b' mRNA 109.86 155.01 122.36 2 2.91 2.45 1.04 0.93 0.75 2.453333333 0.906666667 73.5 61.82 53.22 129.0766667 62.84666667 1.01E-04 -1.056922586 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 27275 27275 'Nufip1' mRNA 258 313 273 7.26 8.22 8.43 11.37 11.15 10.46 7.97 10.99333333 462 445 419 281.3333333 442 4.34E-06 0.640547693 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0008023///transcription elongation factor complex+++GO:0016363///nuclear matrix+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0070761///pre-snoRNP complex "GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030515///snoRNA binding+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding" GO:0000492///box C/D snoRNP assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II 27276 27276 'Plekhb1' mRNA 36976 37731 37453 1169.83 1176.23 1257.23 732.21 704.84 719.9 1201.096667 718.9833333 26600 24965 25291 37386.66667 25618.66667 5.89E-28 -0.558679674 GO:0000139///Golgi membrane+++GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity GO:0007275///multicellular organism development+++GO:0045595///regulation of cell differentiation 27277 27277 'Golga5' mRNA 943 928 959 17.8 17.74 20.09 16.66 16.04 16.7 18.54333333 16.46666667 977 930 954 943.3333333 953.6666667 0.991834759 0.002381953 GO:0000137///Golgi cis cisterna+++GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030663///COPI-coated vesicle membrane+++GO:0031985///Golgi cisterna "GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity" "GO:0000301///retrograde transport, vesicle recycling within Golgi+++GO:0007030///Golgi organization+++GO:0048193///Golgi vesicle transport" 27278 27278 'Clnk' mRNA 1 2 2 0.04 0.07 0.02 0 0.13 0.13 0.043333333 0.086666667 0 4 4 1.666666667 2.666666667 0.771854278 0.675388029 GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0042629///mast cell granule GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0010941///regulation of cell death+++GO:0032815///negative regulation of natural killer cell activation+++GO:0035556///intracellular signal transduction+++GO:0043303///mast cell degranulation 27279 27279 'Tnfrsf12a' mRNA 1571 1533 1473 105.24 101.38 104.6 196.57 189.87 195.26 103.74 193.9 3369 3171 3235 1525.666667 3258.333333 1.52E-64 1.082923029 04060///Cytokine-cytokine receptor interaction GO:0001726///ruffle+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding "GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0006931///substrate-dependent cell migration, cell attachment to substrate+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0045765///regulation of angiogenesis+++GO:0045773///positive regulation of axon extension+++GO:0061041///regulation of wound healing+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 272790 272790 'Magee2' mRNA 12 18 3 0.29 0.43 0.08 0.15 0.13 0.24 0.266666667 0.173333333 7 6 11 11 8 0.696400136 -0.44615808 GO:0005634///nucleus GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 27280 27280 'Phlda3' mRNA 606 657 130 24.49 26.19 5.57 10.49 28.02 22.92 18.75 20.47666667 298 777 630 464.3333333 568.3333333 0.760820633 0.317925706 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1901981///phosphatidylinositol phosphate binding" GO:0006915///apoptotic process+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043065///positive regulation of apoptotic process+++GO:0051898///negative regulation of protein kinase B signaling 27281 27281 'Plaat1' mRNA 351 358 290 6.49 6.49 5.66 1.02 0.99 0.8 6.213333333 0.936666667 64 61 49 333 58 1.03E-37 -2.529963613 GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0008374///O-acyltransferase activity+++GO:0008970///phospholipase A1 activity+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0001558///regulation of cell growth+++GO:0006629///lipid metabolic process+++GO:0007031///peroxisome organization+++GO:0007265///Ras protein signal transduction+++GO:0016042///lipid catabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046485///ether lipid metabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process+++GO:0070306///lens fiber cell differentiation+++GO:1903008///organelle disassembly 27354 27354 'Nbn' mRNA 457.39 491.52 509.54 9.46 9.98 11.21 9.44 11.08 9.99 10.21666667 10.17 510.65 578.14 520.29 486.15 536.36 0.39077625 0.129547042 03440///Homologous recombination+++04218///Cellular senescence "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016605///PML body+++GO:0030870///Mre11 complex+++GO:0035861///site of double-strand break+++GO:0042405///nuclear inclusion body" GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0047485///protein N-terminus binding GO:0000077///DNA damage checkpoint+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001701///in utero embryonic development+++GO:0001832///blastocyst growth+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0008283///cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0031860///telomeric 3' overhang formation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0033674///positive regulation of kinase activity+++GO:0042770///signal transduction in response to DNA damage+++GO:0045190///isotype switching+++GO:0045665///negative regulation of neuron differentiation+++GO:0046597///negative regulation of viral entry into host cell+++GO:0048145///regulation of fibroblast proliferation+++GO:0050885///neuromuscular process controlling balance+++GO:0051321///meiotic cell cycle+++GO:0090656///t-circle formation+++GO:0090737///telomere maintenance via telomere trimming+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1904354///negative regulation of telomere capping 27355 27355 'Pald1' mRNA 674 690 627 8.68 8.73 8.56 11.92 13.09 12.53 8.656666667 12.51333333 1060 1136 1081 663.6666667 1092.333333 2.53E-14 0.709029336 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004725///protein tyrosine phosphatase activity GO:0035335///peptidyl-tyrosine dephosphorylation 27356 27356 'Insl6' mRNA 28 37 33 3.11 4.08 3.88 10.39 10.78 13.79 3.69 11.65333333 107 108 137 32.66666667 117.3333333 1.59E-09 1.833891496 GO:0005576///extracellular region GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0030317///flagellated sperm motility+++GO:0043066///negative regulation of apoptotic process 27357 27357 'Gyg' mRNA 648 647 601 21.81 21.47 21.47 46.23 43.7 44.5 21.58333333 44.81 1580 1456 1470 632 1502 1.42E-49 1.237446461 00500///Starch and sucrose metabolism "GO:0005536///glucose binding+++GO:0008466///glycogenin glucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0102751///UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity" GO:0005978///glycogen biosynthetic process 27359 27359 'Sytl4' mRNA 45 45.35 34 0.71 0.68 0.56 0.62 0.73 0.55 0.65 0.633333333 44.3 54 41.04 41.45 46.44666667 0.750387006 0.159209348 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0070382///exocytic vesicle GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008270///zinc ion binding+++GO:0031267///small GTPase binding+++GO:0042043///neurexin family protein binding+++GO:0046872///metal ion binding GO:0001778///plasma membrane repair+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0032418///lysosome localization+++GO:0045921///positive regulation of exocytosis+++GO:0046676///negative regulation of insulin secretion+++GO:0050714///positive regulation of protein secretion+++GO:0071985///multivesicular body sorting pathway+++GO:1905684///regulation of plasma membrane repair 27360 27360 'Add3' mRNA 6057 6315 6526 77.34 79.23 87.81 101.23 100.85 99.83 81.46 100.6366667 9130 8911 8758 6299.333333 8933 2.06E-14 0.489806449 GO:0000794///condensed nuclear chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005516///calmodulin binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0009410///response to xenobiotic stimulus+++GO:0042493///response to drug+++GO:0045907///positive regulation of vasoconstriction+++GO:0051016///barbed-end actin filament capping 27361 27361 'Msrb1' mRNA 309 313 163 19.77 20.65 11.21 49.96 54.7 50.01 17.21 51.55666667 897 948 873 261.6666667 906 1.14E-28 1.792388215 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton GO:0003779///actin binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0033743///peptide-methionine (R)-S-oxide reductase activity+++GO:0033745///L-methionine-(R)-S-oxide reductase activity+++GO:0046872///metal ion binding+++GO:0070191///methionine-R-sulfoxide reductase activity GO:0002376///immune system process+++GO:0030041///actin filament polymerization+++GO:0030091///protein repair+++GO:0045087///innate immune response 27362 27362 'Dnajb9' mRNA 1764 1863 1953 54.28 56.49 63.75 67.27 64.97 66.28 58.17333333 66.17333333 2513 2369 2396 1860 2426 4.76E-06 0.368627946 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005515///protein binding+++GO:0030544///Hsp70 protein binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding GO:0002639///positive regulation of immunoglobulin production+++GO:0006986///response to unfolded protein+++GO:0030183///B cell differentiation+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response 27364 27364 'Srr' mRNA 1280.03 1357.24 1267.28 12.02 12.33 12.45 7.72 6.64 7.34 12.26666667 7.233333333 984.02 819.02 891.33 1301.516667 898.1233333 9.46E-10 -0.548060383 "00260///Glycine, serine and threonine metabolism+++00470///D-Amino acid metabolism" GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0003941///L-serine ammonia-lyase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008721///D-serine ammonia-lyase activity+++GO:0016594///glycine binding+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0018114///threonine racemase activity+++GO:0030165///PDZ domain binding+++GO:0030170///pyridoxal phosphate binding+++GO:0030378///serine racemase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006520///cellular amino acid metabolic process+++GO:0006563///L-serine metabolic process+++GO:0007420///brain development+++GO:0007568///aging+++GO:0008152///metabolic process+++GO:0009069///serine family amino acid metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0032496///response to lipopolysaccharide+++GO:0042493///response to drug+++GO:0042866///pyruvate biosynthetic process+++GO:0043278///response to morphine+++GO:0070178///D-serine metabolic process+++GO:0070179///D-serine biosynthetic process 27366 27366 'Txnl4a' mRNA 1872.79 1915.55 1959.27 44.22 44.67 49.04 54.3 58.06 53.28 45.97666667 55.21333333 2592.04 2676.41 2458.4 1915.87 2575.616667 8.12E-08 0.41414075 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031415///NatA complex+++GO:0031965///nuclear membrane+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome GO:0003674///molecular_function+++GO:1990189///peptide-serine-N-acetyltransferase activity+++GO:1990190///peptide-glutamate-N-acetyltransferase activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0017198///N-terminal peptidyl-serine acetylation+++GO:0018002///N-terminal peptidyl-glutamic acid acetylation+++GO:0051301///cell division" 27367 27367 'Rpl3' mRNA 7829.8 7934.15 7377 344.58 344.58 344.36 418.92 394.75 433.06 344.5066667 415.5766667 10946.73 10064.48 10946.15 7713.65 10652.45333 9.92E-19 0.454153981 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0009897///external side of plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix GO:0001530///lipopolysaccharide binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0004252///serine-type endopeptidase activity+++GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070053///thrombospondin receptor activity GO:0000027///ribosomal large subunit assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006412///translation+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0009611///response to wounding+++GO:0010468///regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030168///platelet activation+++GO:0030194///positive regulation of blood coagulation+++GO:0030307///positive regulation of cell growth+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0042730///fibrinolysis+++GO:0045861///negative regulation of proteolysis+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051838///cytolysis by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0071353///cellular response to interleukin-4+++GO:0090218///positive regulation of lipid kinase activity+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process 27368 27368 'Tbl2' mRNA 686 690 714 6.54 6.46 7.23 6.39 5.73 6.13 6.743333333 6.083333333 773 675 716 696.6666667 721.3333333 0.80995528 0.035934544 GO:0005783///endoplasmic reticulum GO:0019901///protein kinase binding+++GO:0031369///translation initiation factor binding+++GO:0051219///phosphoprotein binding GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0042149///cellular response to glucose starvation+++GO:0071456///cellular response to hypoxia 27369 27369 'Dguok' mRNA 1069 1102 1003 61.01 61.79 61.42 50 59.27 51.52 61.40666667 53.59666667 994 1154 991 1058 1046.333333 0.863090843 -0.025341852 00230///Purine metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004136///deoxyadenosine kinase activity+++GO:0004138///deoxyguanosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019136///deoxynucleoside kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006170///dAMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006754///ATP biosynthetic process+++GO:0009157///deoxyribonucleoside monophosphate biosynthetic process+++GO:0010977///negative regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0046070///dGTP metabolic process+++GO:0046122///purine deoxyribonucleoside metabolic process 27370 27370 'Rps26' mRNA 1515 1426 1639 309.86 292.81 356.06 428.25 432.19 461.94 319.5766667 440.7933333 2374 2321 2460 1526.666667 2385 7.66E-13 0.628245274 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0033119///negative regulation of RNA splicing 27371 27371 'Sh2d2a' mRNA 8 5 1 0.19 0.12 0.04 0.61 0.59 0.26 0.116666667 0.486666667 27 22 13 4.666666667 20.66666667 0.009249774 2.148508826 04370///VEGF signaling pathway GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0030674///protein binding, bridging" GO:0008283///cell proliferation 27373 27373 'Csnk1e' mRNA 309 319 308 6.18 6.16 6.47 6.63 6.82 7.37 6.27 6.94 382 384 413 312 393 0.025368117 0.321471279 04068///FoxO signaling pathway+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species+++04710///Circadian rhythm+++04711///Circadian rhythm - fly+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0007623///circadian rhythm+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032880///regulation of protein localization+++GO:0032922///circadian regulation of gene expression+++GO:0034613///cellular protein localization+++GO:0042752///regulation of circadian rhythm+++GO:0048511///rhythmic process+++GO:0048512///circadian behavior+++GO:0060070///canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1903827///regulation of cellular protein localization+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway 27374 27374 'Prmt5' mRNA 1131 1163 1164 23.75 24.09 25.92 24.3 26.03 24.8 24.58666667 25.04333333 1328 1392 1316 1152.666667 1345.333333 0.021012494 0.210734598 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0034709///methylosome+++GO:0035097///histone methyltransferase complex GO:0002039///p53 binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008327///methyl-CpG binding+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0070888///E-box binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000387///spliceosomal snRNP assembly+++GO:0006325///chromatin organization+++GO:0006353///DNA-templated transcription, termination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006479///protein methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0032259///methylation+++GO:0032922///circadian regulation of gene expression+++GO:0034969///histone arginine methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0042118///endothelial cell activation+++GO:0043985///histone H4-R3 methylation+++GO:0044030///regulation of DNA methylation+++GO:0045596///negative regulation of cell differentiation+++GO:0048511///rhythmic process+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0090161///Golgi ribbon formation+++GO:0097421///liver regeneration+++GO:1904992///positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway" 27375 27375 'Tjp3' mRNA 770 832 898 13.89 14.77 17.2 9.52 7.89 8.8 15.28666667 8.736666667 604 490 543 833.3333333 545.6666667 1.72E-07 -0.627622148 04530///Tight junction GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding GO:0045216///cell-cell junction organization+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0098609///cell-cell adhesion+++GO:1905605///positive regulation of maintenance of permeability of blood-brain barrier+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 27376 27376 'Slc25a10' mRNA 1105 1075 1039 14.91 14.27 14.87 19.31 19.28 19.56 14.68333333 19.38333333 1647 1606 1616 1073 1623 2.77E-14 0.585473451 04964///Proximal tubule bicarbonate reclamation GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0015114///phosphate ion transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015117///thiosulfate transmembrane transporter activity+++GO:0015131///oxaloacetate transmembrane transporter activity+++GO:0015140///malate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015291///secondary active transmembrane transporter activity+++GO:0015297///antiporter activity GO:0006817///phosphate ion transport+++GO:0006839///mitochondrial transport+++GO:0008272///sulfate transport+++GO:0015709///thiosulfate transport+++GO:0015729///oxaloacetate transport+++GO:0015743///malate transport+++GO:0015744///succinate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0071423///malate transmembrane transport+++GO:1902356///oxaloacetate(2-) transmembrane transport+++GO:1902358///sulfate transmembrane transport 27377 27377 'Yme1l1' mRNA 2052 2167 2185 24.08 25 27.19 22.63 21.6 22.98 25.42333333 22.40333333 2220 2070 2184 2134.666667 2158 0.991558785 0.00197528 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007005///mitochondrion organization+++GO:0008283///cell proliferation+++GO:0034214///protein hexamerization+++GO:0034982///mitochondrial protein processing+++GO:0035694///mitochondrial protein catabolic process+++GO:0043066///negative regulation of apoptotic process 27378 27378 'Tcl1b3' mRNA 0 1 1 0 0.08 0.09 0 0 0 0.056666667 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0032991///protein-containing complex GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity 27381 27381 'Tcl1b2' mRNA 4 8 8 0.25 0.49 0.53 0 0 0 0.423333333 0 0 0 0 6.666666667 0 0.004677689 -5.197475496 04151///PI3K-Akt signaling pathway GO:0032991///protein-containing complex GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity 27384 27384 'Akr1c13' mRNA 38 34 26 1.86 1.55 1.28 5.98 6.02 5.36 1.563333333 5.786666667 140.75 139.85 123.86 32.66666667 134.82 1.18E-12 2.028578046 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018636///phenanthrene 9,10-monooxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0032052///bile acid binding+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0045703///ketoreductase activity+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047042///androsterone dehydrogenase (B-specific) activity+++GO:0047086///ketosteroid monooxygenase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047743///chlordecone reductase activity+++GO:0047787///delta4-3-oxosteroid 5beta-reductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0006805///xenobiotic metabolic process+++GO:0008202///steroid metabolic process 27386 27386 'Npas3' mRNA 782.1 784.48 615.05 2.61 2.79 2.44 0.84 0.71 0.88 2.613333333 0.81 375.29 325.59 359.23 727.21 353.37 1.37E-18 -1.050393552 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity" "GO:0001964///startle response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007626///locomotory behavior+++GO:0042711///maternal behavior+++GO:0045893///positive regulation of transcription, DNA-templated" 27387 27387 'Sh2d3c' mRNA 218 229 223 4.51 4.71 4.92 5.47 6.01 6.32 4.713333333 5.933333333 317 337 363 223.3333333 339 1.59E-04 0.590826668 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse "GO:0001784///phosphotyrosine residue binding+++GO:0004102///choline O-acetyltransferase activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0033265///choline binding" GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007274///neuromuscular synaptic transmission+++GO:0007517///muscle organ development+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0007613///memory+++GO:0007622///rhythmic behavior+++GO:0007628///adult walking behavior+++GO:0008292///acetylcholine biosynthetic process+++GO:0016358///dendrite development+++GO:0030182///neuron differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042136///neurotransmitter biosynthetic process+++GO:0043179///rhythmic excitation+++GO:0050790///regulation of catalytic activity 27388 27388 'Ptdss2' mRNA 1905 1883 1914 49.58 48.32 52.79 33.39 34.92 35.05 50.23 34.45333333 1477 1507 1498 1900.666667 1494 4.18E-06 -0.359876291 00564///Glycerophospholipid metabolism GO:0005622///intracellular+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0016740///transferase activity GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0008654///phospholipid biosynthetic process 27389 27389 'Dusp13' mRNA 4 5 0 0.21 0.2 0 0.13 0.76 0.32 0.136666667 0.403333333 3 16 6 3 8.333333333 0.269290161 1.502976059 GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033549///MAP kinase phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade 27390 27390 'Mmel1' mRNA 16 12 17 0.3 0.22 0.34 0.11 0.1 0.08 0.286666667 0.096666667 7 6 5 15 6 0.104428866 -1.340821223 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0016485///protein processing 27392 27392 'Pign' mRNA 814 892 794 6.83 7.04 6.83 6.02 5.84 5.55 6.9 5.803333333 861 804 765 833.3333333 810 0.685677208 -0.052209983 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0051377///mannose-ethanolamine phosphotransferase activity" GO:0006506///GPI anchor biosynthetic process 27393 27393 'Mrpl39' mRNA 897.02 942.98 750.79 36.01 36.37 34.27 41.29 42.81 42.08 35.55 42.06 986.06 969.23 976.4 863.5966667 977.23 0.097234037 0.170999827 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0000166///nucleotide binding+++GO:0003735///structural constituent of ribosome GO:0000002///mitochondrial genome maintenance+++GO:0006412///translation 27395 27395 'Mrpl15' mRNA 862.91 814.11 921.02 13.72 12.35 15.27 17.11 17.53 18.91 13.78 17.85 1225.47 1195.21 1299.96 866.0133333 1240.213333 5.43E-07 0.503330536 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0000002///mitochondrial genome maintenance+++GO:0006412///translation+++GO:1990830///cellular response to leukemia inhibitory factor 27397 27397 'Mrpl17' mRNA 1758 1799 1696 13.85 13.93 14.17 16.27 15.6 15.46 13.98333333 15.77666667 2379 2229 2190 1751 2266 2.02E-07 0.360069502 03010///Ribosome GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding GO:0000002///mitochondrial genome maintenance+++GO:0006412///translation 27398 27398 'Mrpl2' mRNA 925 929 876 57.16 57.33 58.14 65.37 66.57 62.87 57.54333333 64.93666667 1197 1186 1121 910 1168 6.67E-05 0.348848411 03010///Ribosome GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 27399 27399 'Ip6k1' mRNA 2207 2244 2422 26.87 26.87 31.28 17.7 18.09 19.18 28.34 18.32333333 1673 1671 1756 2291 1700 1.48E-07 -0.444936186 04070///Phosphatidylinositol signaling system GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity" GO:0006020///inositol metabolic process+++GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0120163///negative regulation of cold-induced thermogenesis 27400 27400 'Hsd17b6' mRNA 11.31 24 9.69 0.44 0.92 0.4 0.3 0.22 0.08 0.586666667 0.2 9 6 2 15 5.666666667 0.138612575 -1.373747276 00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047024///5alpha-androstane-3beta,17beta-diol dehydrogenase activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0047044///androstan-3-alpha,17-beta-diol dehydrogenase activity+++GO:0047045///testosterone 17-beta-dehydrogenase (NADP+) activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity" GO:0006629///lipid metabolic process+++GO:0006703///estrogen biosynthetic process+++GO:0007601///visual perception+++GO:0008202///steroid metabolic process+++GO:0042572///retinol metabolic process+++GO:0050896///response to stimulus 27401 27401 'Skp2' mRNA 63 86 72 1.07 1.44 1.3 2.45 2.23 2.39 1.27 2.356666667 166 147 157 73.66666667 156.6666667 5.91E-06 1.077001511 04068///FoxO signaling pathway+++04110///Cell cycle+++04120///Ubiquitin mediated proteolysis+++04150///mTOR signaling pathway+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0042802///identical protein binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0070936///protein K48-linked ubiquitination+++GO:0071460///cellular response to cell-matrix adhesion+++GO:1902916///positive regulation of protein polyubiquitination 27402 27402 'Pdhx' mRNA 668 736 731 14.72 15.97 17.09 13.68 13.73 13.61 15.92666667 13.67333333 714 700 688 711.6666667 700.6666667 0.812407858 -0.035635926 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0045254///pyruvate dehydrogenase complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001889///liver development+++GO:0003309///type B pancreatic cell differentiation+++GO:0006006///glucose metabolic process+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0009749///response to glucose+++GO:0010040///response to iron(II) ion+++GO:0010157///response to chlorate+++GO:0010260///animal organ senescence+++GO:0010468///regulation of gene expression+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0030073///insulin secretion+++GO:0030154///cell differentiation+++GO:0031016///pancreas development+++GO:0031017///exocrine pancreas development+++GO:0031018///endocrine pancreas development+++GO:0031100///animal organ regeneration+++GO:0031667///response to nutrient levels+++GO:0032024///positive regulation of insulin secretion+++GO:0033273///response to vitamin+++GO:0033993///response to lipid+++GO:0034097///response to cytokine+++GO:0035094///response to nicotine+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0043201///response to leucine+++GO:0043279///response to alkaloid+++GO:0043388///positive regulation of DNA binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048565///digestive tract development+++GO:0048863///stem cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0051594///detection of glucose+++GO:0060290///transdifferentiation+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate+++GO:0070542///response to fatty acid+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process" 27403 27403 'Abca7' mRNA 481 448 380 3.79 3.46 3.18 4.27 3.83 4.08 3.476666667 4.06 622 547 578 436.3333333 582.3333333 9.37E-04 0.406925328 02010///ABC transporters GO:0000139///Golgi membrane+++GO:0001891///phagocytic cup+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031901///early endosome membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097386///glial cell projection "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005548///phospholipid transporter activity+++GO:0016887///ATPase activity+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0090556///phosphatidylserine-translocating ATPase activity" GO:0006869///lipid transport+++GO:0006909///phagocytosis+++GO:0007613///memory+++GO:0008542///visual learning+++GO:0010875///positive regulation of cholesterol efflux+++GO:0018149///peptide cross-linking+++GO:0019216///regulation of lipid metabolic process+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034205///amyloid-beta formation+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034504///protein localization to nucleus+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0043409///negative regulation of MAPK cascade+++GO:0044857///plasma membrane raft organization+++GO:0045332///phospholipid translocation+++GO:0045806///negative regulation of endocytosis+++GO:0050766///positive regulation of phagocytosis+++GO:0055085///transmembrane transport+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902991///regulation of amyloid precursor protein catabolic process+++GO:1902995///positive regulation of phospholipid efflux+++GO:1903898///negative regulation of PERK-mediated unfolded protein response+++GO:2000010///positive regulation of protein localization to cell surface 27404 27404 'Abca8b' mRNA 118 111 110 1.26 1.41 0.94 1.14 1.16 1.29 1.203333333 1.196666667 156 125 169 113 150 0.10150787 0.395828636 02010///ABC transporters GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006686///sphingomyelin biosynthetic process+++GO:0006810///transport+++GO:0006869///lipid transport+++GO:0010874///regulation of cholesterol efflux+++GO:0010875///positive regulation of cholesterol efflux+++GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport 27405 27405 'Abcg3' mRNA 10 4 7 0.19 0.09 0.13 1.22 0.97 1.02 0.136666667 1.07 77 60 62 7 66.33333333 7.69E-11 3.229357781 02010///ABC transporters GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0045121///membrane raft "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015143///urate transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0032217///riboflavin transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity" GO:0015747///urate transport+++GO:0032218///riboflavin transport+++GO:0046415///urate metabolic process+++GO:0055085///transmembrane transport+++GO:0070633///transepithelial transport+++GO:0097744///urate salt excretion+++GO:1990748///cellular detoxification+++GO:1990962///drug transport across blood-brain barrier 27406 27406 'Abcf3' mRNA 1541 1634 1577 25.59 26.69 27.78 20.69 23.03 22.41 26.68666667 22.04333333 1434 1559 1504 1584 1499 0.352200633 -0.090921059 "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0051607///defense response to virus 27407 27407 'Abcf2' mRNA 1555 1643 1658 33.54 34.81 37.86 35.58 39.64 38.22 35.40333333 37.81333333 1910 2072 1992 1618.666667 1991.333333 8.10E-04 0.28655217 05130///Pathogenic Escherichia coli infection GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0008150///biological_process 27409 27409 'Abcg5' mRNA 2 0 0 0.05 0 0 0.02 0 0.04 0.016666667 0.02 1 0 2 0.666666667 1 0.874307774 0.589641014 02010///ABC transporters+++04975///Fat digestion and absorption+++04976///Bile secretion+++04979///Cholesterol metabolism GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0043235///receptor complex+++GO:0045177///apical part of cell "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0120020///intermembrane cholesterol transfer activity" GO:0006869///lipid transport+++GO:0007584///response to nutrient+++GO:0007588///excretion+++GO:0010212///response to ionizing radiation+++GO:0010949///negative regulation of intestinal phytosterol absorption+++GO:0014850///response to muscle activity+++GO:0015918///sterol transport+++GO:0030299///intestinal cholesterol absorption+++GO:0031667///response to nutrient levels+++GO:0033344///cholesterol efflux+++GO:0038183///bile acid signaling pathway+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0045796///negative regulation of intestinal cholesterol absorption+++GO:0055085///transmembrane transport+++GO:0070328///triglyceride homeostasis+++GO:0120009///intermembrane lipid transfer 27410 27410 'Abca3' mRNA 1768 1799 1593 14.46 14.49 13.86 12.13 11.21 12.23 14.27 11.85666667 1704 1540 1666 1720 1636.666667 0.34198815 -0.082241527 02010///ABC transporters GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0032585///multivesicular body membrane+++GO:0042599///lamellar body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097208///alveolar lamellar body+++GO:0097232///lamellar body membrane+++GO:0097233///alveolar lamellar body membrane "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0120019///intermembrane phosphotidylcholine transfer activity" GO:0006810///transport+++GO:0006855///drug transmembrane transport+++GO:0006869///lipid transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:0015914///phospholipid transport+++GO:0030324///lung development+++GO:0032368///regulation of lipid transport+++GO:0032464///positive regulation of protein homooligomerization+++GO:0034204///lipid translocation+++GO:0042908///xenobiotic transport+++GO:0043129///surfactant homeostasis+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0046618///drug export+++GO:0046890///regulation of lipid biosynthetic process+++GO:0051384///response to glucocorticoid+++GO:0055085///transmembrane transport+++GO:0055091///phospholipid homeostasis+++GO:0070925///organelle assembly+++GO:0120009///intermembrane lipid transfer+++GO:1902995///positive regulation of phospholipid efflux+++GO:2001140///positive regulation of phospholipid transport 27411 27411 'Slc14a2' mRNA 3 1 7 0.13 0.04 0.21 0.22 0.19 0.23 0.126666667 0.213333333 7 7 6 3.666666667 6.666666667 0.549659963 0.823725325 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0015204///urea transmembrane transporter activity+++GO:0050839///cell adhesion molecule binding GO:0015840///urea transport+++GO:0071918///urea transmembrane transport 27412 27412 'Peg12' mRNA 30 29 38 0.63 0.6 0.85 1.17 1.5 1.34 0.693333333 1.336666667 64 80 71 32.33333333 71.66666667 0.00169144 1.133393727 04310///Wnt signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05200///Pathways in cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000578///embryonic axis specification+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway 27414 27414 'Sergef' mRNA 303.84 329.27 261.85 7.32 7.88 6.87 9.27 9.12 9.24 7.356666667 9.21 412.08 401.3 433.3 298.32 415.56 7.58E-04 0.472265581 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005085///guanyl-nucleotide exchange factor activity GO:0050709///negative regulation of protein secretion+++GO:0050790///regulation of catalytic activity 27416 27416 'Abcc5' mRNA 2115 2261 2135 28.71 27.34 31.75 22.84 21.58 23.05 29.26666667 22.49 2104 1710 1949 2170.333333 1921 0.027549749 -0.189537951 01523///Antifolate resistance+++02010///ABC transporters GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015216///purine nucleotide transmembrane transporter activity+++GO:0015232///heme transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0034634///glutathione transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity" GO:0015711///organic anion transport+++GO:0015865///purine nucleotide transport+++GO:0034775///glutathione transmembrane transport+++GO:0035351///heme transmembrane transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0070730///cAMP transport+++GO:0070731///cGMP transport+++GO:0098838///folate transmembrane transport+++GO:0140115///export across plasma membrane 27418 27418 'Mkln1' mRNA 1979.86 1995.42 1775.07 17.51 17.09 17.71 20.03 19.13 17.36 17.43666667 18.84 2134 2018.65 1907.97 1916.783333 2020.206667 0.453702353 0.065273954 GO:0000151///ubiquitin ligase complex+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0002090///regulation of receptor internalization+++GO:0007160///cell-matrix adhesion+++GO:0008360///regulation of cell shape+++GO:0031532///actin cytoskeleton reorganization 27419 27419 'Naglu' mRNA 1256 1315 1193 28.31 29.16 28.53 53.03 53.74 51.93 28.66666667 52.9 2704 2674 2567 1254.666667 2648.333333 5.01E-55 1.067051891 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0070062///extracellular exosome "GO:0004561///alpha-N-acetylglucosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0007040///lysosome organization+++GO:0008152///metabolic process+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0042474///middle ear morphogenesis+++GO:0045475///locomotor rhythm+++GO:0046548///retinal rod cell development+++GO:0060119///inner ear receptor cell development 27421 27421 'Abcc6' mRNA 24 25 11 0.37 0.32 0.13 0.39 0.29 0.3 0.273333333 0.326666667 32 30 29 20 30.33333333 0.299470697 0.601309883 02010///ABC transporters GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0016887///ATPase activity+++GO:0030504///inorganic diphosphate transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006855///drug transmembrane transport+++GO:0015867///ATP transport+++GO:0030505///inorganic diphosphate transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0071716///leukotriene transport 27425 27425 'Atp5l' mRNA 2787 2593 3178 452.81 420.76 548.41 540.76 617.77 555.17 473.9933333 571.2333333 3786 4198 3741 2852.666667 3908.333333 8.71E-06 0.437903897 00190///Oxidative phosphorylation+++04714///Thermogenesis "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015078///proton transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process 27426 27426 'Nagpa' mRNA 523 512 490 13.58 13.07 13.33 30.91 29.21 28.34 13.32666667 29.48666667 1367 1263 1210 508.3333333 1280 2.02E-46 1.320336082 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0003944///N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity+++GO:0016787///hydrolase activity GO:0006486///protein glycosylation+++GO:0033299///secretion of lysosomal enzymes 27428 27428 'Shroom3' mRNA 768 835 421 6.12 6.74 3.62 3.58 3.58 4.03 5.493333333 3.73 509 490 561 674.6666667 520 0.044883213 -0.373651192 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0045177///apical part of cell GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0001843///neural tube closure+++GO:0002064///epithelial cell development+++GO:0002066///columnar/cuboidal epithelial cell development+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0008360///regulation of cell shape+++GO:0030036///actin cytoskeleton organization+++GO:0043482///cellular pigment accumulation+++GO:0045176///apical protein localization 27494 27494 'Amot' mRNA 663 550 486 5.95 3.94 4.45 5.14 4 4.3 4.78 4.48 761 523 617 566.3333333 633.6666667 0.369212911 0.150588003 04390///Hippo signaling pathway+++04530///Tight junction GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0008180///COP9 signalosome+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0043532///angiostatin binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001702///gastrulation with mouth forming second+++GO:0003365///establishment of cell polarity involved in ameboidal cell migration+++GO:0006935///chemotaxis+++GO:0016525///negative regulation of angiogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0034260///negative regulation of GTPase activity+++GO:0034613///cellular protein localization+++GO:0035329///hippo signaling+++GO:0040019///positive regulation of embryonic development+++GO:0042074///cell migration involved in gastrulation+++GO:0043116///negative regulation of vascular permeability+++GO:0043534///blood vessel endothelial cell migration+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0048514///blood vessel morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction 27528 27528 'Nrep' mRNA 1428 1496 1394 38.32 39.57 39.78 37.06 32.99 33.99 39.22333333 34.68 1584 1377 1411 1439.333333 1457.333333 0.962760552 0.005455524 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0031103///axon regeneration+++GO:0045664///regulation of neuron differentiation 27632 27632 'Nelfe' mRNA 918 955 874 37.37 38.4 37.9 36.06 34.47 37.19 37.89 35.90666667 1012 939 1019 915.6666667 990 0.329615796 0.101390374 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0032021///NELF complex GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1900364///negative regulation of mRNA polyadenylation" 27643 27643 'Ubl4a' mRNA 1331.14 1360.21 1314.51 32.23 32.43 33.76 30.92 35.76 32.05 32.80666667 32.91 1469 1658.56 1473.78 1335.286667 1533.78 0.044037604 0.189013 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0071818///BAT3 complex GO:0051087///chaperone binding GO:0071816///tail-anchored membrane protein insertion into ER membrane 27660 27660 '1700088E04Rik' mRNA 599.34 622.78 684.37 33.4 34.05 40.1 16.08 14.76 13.31 35.85 14.71666667 333.63 293.44 265.08 635.4966667 297.3833333 1.79E-16 -1.112729931 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 276770 276770 'Eif5a' mRNA 7980.49 8542.24 8258.17 357.48 379.34 395.11 563.06 602.68 574.82 377.31 580.1866667 14268.42 14919.83 14083.89 8260.3 14424.04667 2.25E-41 0.79220748 GO:0005634///nucleus+++GO:0005642///annulate lamellae+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003746///translation elongation factor activity+++GO:0017070///U6 snRNA binding+++GO:0043022///ribosome binding+++GO:0047485///protein N-terminus binding GO:0006406///mRNA export from nucleus+++GO:0006412///translation+++GO:0006414///translational elongation+++GO:0006611///protein export from nucleus+++GO:0006915///apoptotic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0015031///protein transport+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045901///positive regulation of translational elongation+++GO:0045905///positive regulation of translational termination+++GO:0051028///mRNA transport+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:2000379///positive regulation of reactive oxygen species metabolic process 27681 27681 'Snf8' mRNA 227 209 131 11.64 10.54 6.38 7.49 8.91 9.99 9.52 8.796666667 174 196 213 189 194.3333333 0.887154404 0.039094422 04144///Endocytosis GO:0000814///ESCRT II complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016247///channel regulator activity+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0010797///regulation of multivesicular body size involved in endosome transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042176///regulation of protein catabolic process+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0045022///early endosome to late endosome transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0061635///regulation of protein complex stability+++GO:0071985///multivesicular body sorting pathway+++GO:1903543///positive regulation of exosomal secretion+++GO:1903772///regulation of viral budding via host ESCRT complex 276829 276829 'Smtnl2' mRNA 2006.9 2179.99 2044.02 41.85 44.47 44.92 22.5 25.63 25.05 43.74666667 24.39333333 1253.96 1392.11 1345.39 2076.97 1330.486667 1.03E-15 -0.653348349 GO:0005815///microtubule organizing center+++GO:0031430///M band+++GO:0031674///I band+++GO:0031941///filamentous actin GO:0005523///tropomyosin binding+++GO:0008157///protein phosphatase 1 binding GO:0030036///actin cytoskeleton organization+++GO:0045907///positive regulation of vasoconstriction 276846 276846 'Pigs' mRNA 3478 3537 3567 78.13 78.22 84.77 68.49 74.53 72.42 80.37333333 71.81333333 3508 3715 3595 3527.333333 3606 0.851719614 0.019463775 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042765///GPI-anchor transamidase complex GO:0006506///GPI anchor biosynthetic process+++GO:0016255///attachment of GPI anchor to protein 276852 276852 'D11Wsu47e' mRNA 399.15 344.1 386.17 10.17 8.5 10.48 9.78 8.54 9.73 9.716666667 9.35 449.82 392.24 438.92 376.4733333 426.9933333 0.295280438 0.165444301 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 276891 276891 'Timd4' mRNA 12 11 9 0.51 0.29 0.29 0.52 0.46 0.4 0.363333333 0.46 14 18 17 10.66666667 16.33333333 0.436284536 0.608792741 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding GO:0043277///apoptotic cell clearance 276905 276905 'Armc7' mRNA 264.9 288.07 322.25 8.94 8.61 11.23 14.58 15.56 14.37 9.593333333 14.83666667 478.76 494.24 460.04 291.74 477.68 1.33E-06 0.697265862 GO:0008150///biological_process 276919 276919 'Gemin4' mRNA 251 223 255 3.96 3.46 4.27 3.8 3.68 3.43 3.896666667 3.636666667 277 262 242 243 260.3333333 0.70345483 0.084617691 GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex GO:0043021///ribonucleoprotein complex binding GO:0000387///spliceosomal snRNP assembly+++GO:0006364///rRNA processing 276920 276920 'Ccdc42' mRNA 15 26 12 0.67 1.14 0.57 0.35 0.44 0.32 0.793333333 0.37 9 11 8 17.66666667 9.333333333 0.231441412 -0.919598039 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007286///spermatid development 276950 276950 'Slfn8' mRNA 135.87 167.3 156.93 1.91 2.27 2.28 9.34 9.26 9.5 2.153333333 9.366666667 774.48 752.85 761.78 153.3666667 763.0366667 2.99E-69 2.308003204 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0090734///site of DNA damage GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0016075///rRNA catabolic process+++GO:0016078///tRNA catabolic process+++GO:0051607///defense response to virus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 276952 276952 'Rasl10b' mRNA 19 20 14 0.33 0.34 0.26 0.26 0.34 0.31 0.31 0.303333333 17 22 20 17.66666667 19.66666667 0.856862268 0.150806042 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0003050///regulation of systemic arterial blood pressure by atrial natriuretic peptide+++GO:0090277///positive regulation of peptide hormone secretion 277010 277010 'Marveld1' mRNA 249 264 198 4.44 4.63 3.74 4.69 4.69 4.48 4.27 4.62 303 296 280 237 293 0.081852168 0.298701908 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019911///structural constituent of myelin sheath GO:0007049///cell cycle+++GO:0042552///myelination 277154 277154 'Nynrin' mRNA 861 1020 772 6.12 7.13 5.82 3.82 4.28 4.29 6.356666667 4.13 618 677 673 884.3333333 656 1.05E-04 -0.43748142 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0004521///endoribonuclease activity "GO:0015074///DNA integration+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 277203 277203 'Tm4sf19' mRNA 0 0 1 0 0 0.06 3.56 3.19 3 0.02 3.25 85 76 70 0.333333333 77 1.27E-09 7.734762067 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 277250 277250 'Kdm3b' mRNA 1269 1286 1175 9.42 9.38 9.25 6.24 6.03 6.1 9.35 6.123333333 968 914 917 1243.333333 933 3.00E-07 -0.425255844 04714///Thermogenesis GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003712///transcription coregulator activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0033169///histone H3-K9 demethylation+++GO:0072718///response to cisplatin+++GO:0098869///cellular oxidant detoxification 277343 277343 'Wfdc8' mRNA 4 8 6 0.14 0.15 0.16 0 0 0 0.15 0 0 0 0 6 0 0.007919946 -5.038162797 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0008150///biological_process+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0043086///negative regulation of catalytic activity+++GO:0052547///regulation of peptidase activity 277345 277345 'Wfdc16' mRNA 32 40 16 1.72 2.2 0.94 0.24 0.2 0.45 1.62 0.296666667 5 4 9 29.33333333 6 8.46E-04 -2.285230705 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 277353 277353 'Tcfl5' mRNA 6.14 3.01 1 0.18 0.09 0.03 0.23 0.14 0.21 0.1 0.193333333 10.03 6.16 9.13 3.383333333 8.44 0.272826728 1.322167811 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0042127///regulation of cell proliferation+++GO:0045595///regulation of cell differentiation" 277360 277360 'Prex1' mRNA 360 403 241 2.92 3.21 2.07 4.31 4.8 4.9 2.733333333 4.67 613 666 675 334.6666667 651.3333333 1.24E-10 0.958897963 04062///Chemokine signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone+++GO:0043198///dendritic shaft+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0051059///NF-kappaB binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0018022///peptidyl-lysine methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0019827///stem cell population maintenance+++GO:0030217///T cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0030833///regulation of actin filament polymerization+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0048863///stem cell differentiation+++GO:0050727///regulation of inflammatory response+++GO:0050773///regulation of dendrite development+++GO:0050790///regulation of catalytic activity+++GO:0072593///reactive oxygen species metabolic process+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 277396 277396 'Klhl23' mRNA 411 413 460 4.86 4.85 5.77 4.42 4.96 4.33 5.16 4.57 427 468 407 428 434 0.979885539 0.005890256 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 277414 277414 'Trp53i11' mRNA 2731 3010 2645 54.92 59.45 56.58 50.87 45.95 47.03 56.98333333 47.95 2911 2584 2620 2795.333333 2705 0.485291592 -0.058790713 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 277432 277432 'Vstm2l' mRNA 0 2 0 0 0.09 0 0 0 0.04 0.03 0.013333333 0 0 1 0.666666667 0.333333333 0.863090843 -0.864730756 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030424///axon GO:0098632///cell-cell adhesion mediator activity GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070593///dendrite self-avoidance 277463 277463 'Gpr107' mRNA 1042 1120 1121 14.34 15.16 16.37 19.69 17.12 17 15.29 17.93666667 1647 1399 1377 1094.333333 1474.333333 1.16E-05 0.415269169 GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle GO:0005515///protein binding+++GO:0032050///clathrin heavy chain binding GO:0006810///transport+++GO:0072583///clathrin-dependent endocytosis 277468 277468 'Slc39a12' mRNA 6 3 10 0.15 0.06 0.25 0.22 0.11 0.13 0.153333333 0.153333333 12 6 7 6.333333333 8.333333333 0.77544629 0.359377756 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006882///cellular zinc ion homeostasis+++GO:0007165///signal transduction+++GO:0010975///regulation of neuron projection development+++GO:0030001///metal ion transport+++GO:0031113///regulation of microtubule polymerization+++GO:0036293///response to decreased oxygen levels+++GO:0055085///transmembrane transport+++GO:0071578///zinc ion import across plasma membrane+++GO:1903672///positive regulation of sprouting angiogenesis 27756 27756 'Lsm2' mRNA 287 242 254 22.01 18.39 20.69 38.97 32.58 34.96 20.36333333 35.50333333 582 474 504 261 520 1.41E-12 0.980803614 03018///RNA degradation+++03040///Spliceosome GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005737///cytoplasm+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0120115///Lsm2-8 complex+++GO:1990726///Lsm1-7-Pat1 complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0008380///RNA splicing" 27762 27762 'Vwa7' mRNA 126.19 139.3 190.18 1.55 1.69 2.51 0.95 0.88 0.8 1.916666667 0.876666667 89.36 79.29 72.03 151.89 80.22666667 3.69E-04 -0.944907967 GO:0005576///extracellular region 277743 277743 'Fam131c' mRNA 56 52 11 2.28 2.08 0.47 0.35 0.36 0.59 1.61 0.433333333 10 10 16 39.66666667 12 0.007192822 -1.710571711 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 277744 277744 'Srarp' mRNA 12 4 3 0.87 0.29 0.23 0.51 0.39 0.26 0.463333333 0.386666667 8 6 4 6.333333333 6 0.954691516 -0.080880667 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0030331///estrogen receptor binding GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway 277773 277773 'Fam205c' mRNA 7 4 1 0.28 0.16 0.04 0.11 0.07 0.04 0.16 0.073333333 3 2 1 4 2 0.585667376 -0.994718366 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 27784 27784 'Commd8' mRNA 1033.98 1103.64 1004.04 14.26 14.94 14.64 19.79 21.82 19.87 14.61333333 20.49333333 1655.13 1782.13 1609.67 1047.22 1682.31 5.36E-16 0.674152271 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 277854 277854 'Depdc5' mRNA 611.95 614.52 623.2 4.94 5.04 5.11 3.49 3.31 3.6 5.03 3.466666667 501.21 460.38 461 616.5566667 474.1966667 7.64E-04 -0.391486228 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:1990130///GATOR1 complex GO:0005096///GTPase activator activity+++GO:0044877///protein-containing complex binding GO:0010506///regulation of autophagy+++GO:0032007///negative regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1904262///negative regulation of TORC1 signaling 277898 277898 'Slc15a5' mRNA 195 182 219 5.61 5.33 6.41 1.42 1.1 1.21 5.783333333 1.243333333 57 45 58 198.6666667 53.33333333 9.61E-16 -1.914628758 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0055085///transmembrane transport 277939 277939 'C2cd3' mRNA 920 930 809 6.21 6.18 5.86 3.96 3.22 3.41 6.083333333 3.53 673 536 563 886.3333333 590.6666667 2.29E-08 -0.596877395 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0001947///heart looping+++GO:0007389///pattern specification process+++GO:0007420///brain development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0016485///protein processing+++GO:0021915///neural tube development+++GO:0021997///neural plate axis specification+++GO:0030030///cell projection organization+++GO:0030162///regulation of proteolysis+++GO:0030326///embryonic limb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0060271///cilium assembly+++GO:0061511///centriole elongation+++GO:0071539///protein localization to centrosome+++GO:1905515///non-motile cilium assembly 277973 277973 'Slc9a5' mRNA 17 12 14 0.25 0.17 0.23 0.61 0.54 0.49 0.216666667 0.546666667 54 41 39 14.33333333 44.66666667 7.10E-04 1.625013182 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 277978 277978 'Exoc3l' mRNA 35 48 34 0.73 1.02 0.87 1.63 1.68 1.72 0.873333333 1.676666667 85 86 84 39 85 5.44E-04 1.116263758 GO:0000145///exocyst+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle GO:0000149///SNARE binding+++GO:0005515///protein binding GO:0006887///exocytosis+++GO:0030072///peptide hormone secretion+++GO:0051601///exocyst localization 27801 27801 'Zdhhc8' mRNA 839.1 930.76 775.47 8.86 9.51 8.52 6.74 6.37 6.49 8.963333333 6.533333333 731.99 685.2 683 848.4433333 700.0633333 0.004812492 -0.287166552 GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0005515///protein binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0007626///locomotory behavior+++GO:0010875///positive regulation of cholesterol efflux+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation 278097 278097 'Armcx6' mRNA 398 417 359 10.95 11.38 10.43 6.35 5.97 6.45 10.92 6.256666667 264 248 262 391.3333333 258 1.27E-05 -0.610957328 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 278180 278180 'Vsig4' mRNA 1 1 0 0.04 0.04 0 0.69 0.44 0.49 0.026666667 0.54 19 12 13 0.666666667 14.66666667 0.001221229 4.452359533 04610///Complement and coagulation cascades GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0001851///complement component C3b binding "GO:0032703///negative regulation of interleukin-2 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0043031///negative regulation of macrophage activation+++GO:0045957///negative regulation of complement activation, alternative pathway" 278203 278203 'Spaca5' mRNA 1 1 0 0.12 0.12 0 0 0 0 0.08 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005576///extracellular region "GO:0003796///lysozyme activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0008152///metabolic process 278240 278240 'Spin2c' mRNA 44 38 36 2.04 1.65 1.7 2.09 2.86 2.08 1.796666667 2.343333333 54 70 52 39.33333333 58.66666667 0.145232676 0.568578673 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007276///gamete generation+++GO:0051726///regulation of cell cycle" 278255 278255 'Tex13c3' mRNA 2 1 0 0.15 0.07 0 0 0.07 0 0.073333333 0.023333333 0 1 0 1 0.333333333 0.734312035 -1.462250413 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 278279 278279 'Tmtc2' mRNA 390 366 204 3.65 3.37 2.03 0.75 0.98 1.46 3.016666667 1.063333333 92 118 174 320 128 1.62E-07 -1.318201012 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity GO:0006486///protein glycosylation+++GO:0035269///protein O-linked mannosylation+++GO:0055074///calcium ion homeostasis 278304 278304 'Zfp385c' mRNA 104.37 124.41 83.78 1.98 2.03 1.68 0.51 0.62 0.39 1.896666667 0.506666667 37.29 46.01 23.47 104.1866667 35.59 3.17E-06 -1.556982266 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding 278507 278507 'Wfikkn2' mRNA 740 795 645 11.71 12.39 10.79 4.56 3.17 3.62 11.63 3.783333333 335 225 261 726.6666667 273.6666667 4.59E-25 -1.420282516 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004857///enzyme inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0048019///receptor antagonist activity+++GO:0050431///transforming growth factor beta binding GO:0001501///skeletal system development+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0043392///negative regulation of DNA binding+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0060021///roof of mouth development+++GO:2000272///negative regulation of signaling receptor activity 278672 278672 'Duxbl1' mRNA 153.71 156.5 145.42 2.21 2.16 2.17 1.95 1.61 1.55 2.18 1.703333333 159.84 124.58 120.27 151.8766667 134.8966667 0.47154993 -0.185099203 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045580///regulation of T cell differentiation 278679 278679 'Apol7b' mRNA 5.5 2.5 2.22 0.14 0.06 0.06 0.07 0.07 0.09 0.086666667 0.076666667 3 3 4 3.406666667 3.333333333 0.934424812 0.147508665 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 27878 27878 'Tada1' mRNA 830.63 806.57 850.06 21.89 20.93 23.77 23.71 21.2 21.23 22.19666667 22.04666667 1034.52 902.65 896.52 829.0866667 944.5633333 0.115876958 0.173349218 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030914///STAGA complex+++GO:0070461///SAGA-type complex GO:0003713///transcription coactivator activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated" 278795 278795 'Lrrc10b' mRNA 1429 1425 1162 39.01 38.32 33.65 3.85 3.41 4.37 36.99333333 3.876666667 162 140 178 1338.666667 160 1.14E-147 -3.072976016 GO:0005575///cellular_component GO:0003674///molecular_function 27883 27883 'Tango2' mRNA 853.14 807.85 783.99 27.76 25.13 27.5 22.14 26.78 25.55 26.79666667 24.82333333 784.97 877.04 858.97 814.9933333 840.3266667 0.813186855 0.033977551 GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus GO:0003674///molecular_function GO:0007030///Golgi organization+++GO:0009306///protein secretion 27886 27886 'Ess2' mRNA 753 727 820 18.02 18.22 21.74 14.17 15.27 16.73 19.32666667 15.39 681 691 733 766.6666667 701.6666667 0.269875516 -0.142438525 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome GO:0003674///molecular_function GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0008380///RNA splicing 279028 279028 'Adamts13' mRNA 7.45 11.96 9.1 0.1 0.16 0.12 0.05 0.06 0.04 0.126666667 0.05 4.03 6 4 9.503333333 4.676666667 0.379100058 -0.956128221 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0009636///response to toxic substance+++GO:0014075///response to amine+++GO:0030198///extracellular matrix organization+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:0035864///response to potassium ion+++GO:0043171///peptide catabolic process+++GO:0070670///response to interleukin-4+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma+++GO:0071353///cellular response to interleukin-4+++GO:0071356///cellular response to tumor necrosis factor 279029 279029 'Stkld1' mRNA 8 4 6 0.21 0.11 0.16 0.2 0.21 0.3 0.16 0.236666667 9 9 13 6 10.33333333 0.451091164 0.771403699 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation 279185 279185 'Pramel21' mRNA 1 1 1 0.02 0.02 0.02 0 0 0 0.02 0 0 0 0 1 0 0.568344116 -2.455252046 GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 279499 279499 'Kctd19' mRNA 4 4 1 0.07 0.07 0.02 0.05 0.08 0.12 0.053333333 0.083333333 3 5 7 3 5 0.636398589 0.747725891 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0051260///protein homooligomerization 279561 279561 'Wnk3' mRNA 108.45 84.82 115.49 0.49 0.37 0.55 0.23 0.15 0.24 0.47 0.206666667 56 38 58 102.92 50.66666667 9.41E-04 -1.033618106 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019870///potassium channel inhibitor activity GO:0006468///protein phosphorylation+++GO:0006884///cell volume homeostasis+++GO:0007231///osmosensory signaling pathway+++GO:0010765///positive regulation of sodium ion transport+++GO:0010766///negative regulation of sodium ion transport+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0016310///phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0035556///intracellular signal transduction+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0043066///negative regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0050801///ion homeostasis+++GO:0051928///positive regulation of calcium ion transport+++GO:0072659///protein localization to plasma membrane+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0090279///regulation of calcium ion import+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903288///positive regulation of potassium ion import+++GO:1904062///regulation of cation transmembrane transport+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 279572 279572 'Tlr13' mRNA 49 85 79 0.66 1.12 1.13 16.79 17.39 14.5 0.97 16.22666667 1437 1454 1202 71 1364.333333 6.20E-165 4.251499872 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005887///integral component of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003723///RNA binding+++GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0009615///response to virus+++GO:0034178///toll-like receptor 13 signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0045087///innate immune response 279618 279618 'Gm715' mRNA 2 2 1 0.1 0.1 0.05 0.18 0 0.14 0.083333333 0.106666667 4 0 3 1.666666667 2.333333333 0.858994091 0.472140542 27965 27965 'Spg21' mRNA 2543 2598 2563 52.29 52.53 55.87 52.32 53.95 51.94 53.56333333 52.73666667 2932 2954 2815 2568 2900.333333 0.023154651 0.163240128 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030140///trans-Golgi network transport vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0042609///CD4 receptor binding GO:0008150///biological_process 279653 279653 'Pcdh19' mRNA 116 110 78 0.6 0.58 0.45 1.07 1.03 1.05 0.543333333 1.05 226 212 224 101.3333333 220.6666667 4.76E-08 1.116462696 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007420///brain development 27966 27966 'Rrp9' mRNA 414 445 410 15.86 16.81 16.66 17.14 17.87 19.13 16.44333333 18.04666667 514 523 555 423 530.6666667 0.011537121 0.316368412 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0031428///box C/D snoRNP complex+++GO:0032040///small-subunit processome GO:0003723///RNA binding+++GO:0030515///snoRNA binding+++GO:0034511///U3 snoRNA binding GO:0006364///rRNA processing 27967 27967 'Cherp' mRNA 1578 1716 1418 22.45 24.02 21.38 17.38 17.75 15.43 22.61666667 16.85333333 1407 1403 1209 1570.666667 1339.666667 0.009608145 -0.23854603 03040///Spliceosome GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding GO:0006396///RNA processing+++GO:0006874///cellular calcium ion homeostasis+++GO:0008285///negative regulation of cell proliferation+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 279706 279706 'Nup62cl' mRNA 25 21 19 0.79 0.65 0.64 0.25 0.25 0.23 0.693333333 0.243333333 9 9 8 21.66666667 8.666666667 0.046901787 -1.331025916 GO:0005643///nuclear pore+++GO:0044613///nuclear pore central transport channel GO:0005543///phospholipid binding+++GO:0017056///structural constituent of nuclear pore GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport 27973 27973 'Vkorc1' mRNA 1606 1622 1498 151.96 152.06 150.09 209.17 216.58 207.76 151.37 211.17 2529 2565 2419 1575.333333 2504.333333 6.20E-22 0.658141924 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016491///oxidoreductase activity+++GO:0047057///vitamin-K-epoxide reductase (warfarin-sensitive) activity+++GO:0047058///vitamin-K-epoxide reductase (warfarin-insensitive) activity+++GO:0048038///quinone binding GO:0006805///xenobiotic metabolic process+++GO:0007596///blood coagulation+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0017144///drug metabolic process+++GO:0017187///peptidyl-glutamic acid carboxylation+++GO:0030193///regulation of blood coagulation+++GO:0042371///vitamin K biosynthetic process+++GO:0042373///vitamin K metabolic process+++GO:0046677///response to antibiotic+++GO:0050820///positive regulation of coagulation+++GO:0060348///bone development 279766 279766 'Rhbdd3' mRNA 543.17 603 544 16.96 18.46 18.38 15.11 13.88 14.86 17.93333333 14.61666667 570.19 493.14 529.64 563.39 530.99 0.482095543 -0.098232281 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding GO:0000165///MAPK cascade+++GO:0001889///liver development+++GO:0002673///regulation of acute inflammatory response+++GO:0006508///proteolysis+++GO:0009410///response to xenobiotic stimulus+++GO:0032815///negative regulation of natural killer cell activation+++GO:0045732///positive regulation of protein catabolic process+++GO:0050708///regulation of protein secretion 27979 27979 'Eif3b' mRNA 1170 1133 475 21.69 20.67 9.34 12.26 13.46 13.66 17.23333333 13.12666667 761 816 821 926 799.3333333 0.689442381 -0.204344684 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0045202///synapse+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0031369///translation initiation factor binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0075522///IRES-dependent viral translational initiation+++GO:0075525///viral translational termination-reinitiation 27981 27981 'Rsrp1' mRNA 8365 8239 8255 352.53 342.58 369.1 297.54 309.67 298.64 354.7366667 301.95 8108 8233 7872 8286.333333 8071 0.480629637 -0.050416574 GO:0005575///cellular_component GO:0008150///biological_process 27984 27984 'Efhd2' mRNA 1025 945 494 24.09 21.87 12.32 22.99 23.98 25.94 19.42666667 24.30333333 1125 1146 1229 821.3333333 1166.666667 0.118338596 0.509829237 GO:0016020///membrane+++GO:0045121///membrane raft GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding 27993 27993 'Imp4' mRNA 616 600 609 15.67 15.15 16.54 24.2 22.77 22.27 15.78666667 23.08 1096.06 997 969.09 608.3333333 1020.716667 5.05E-14 0.733287179 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030684///preribosome+++GO:0032040///small-subunit processome+++GO:0034457///Mpp10 complex GO:0019843///rRNA binding+++GO:0030515///snoRNA binding+++GO:0042134///rRNA primary transcript binding GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 27998 27998 'Exosc5' mRNA 726 710 653 44.69 43.21 42.65 44.93 48.9 43.99 43.51666667 45.94 837 888 792 696.3333333 839 0.014304176 0.25889482 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin GO:0003674///molecular_function+++GO:0003723///RNA binding "GO:0006364///rRNA processing+++GO:0006401///RNA catabolic process+++GO:0016075///rRNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045006///DNA deamination+++GO:0051607///defense response to virus+++GO:0071028///nuclear mRNA surveillance+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing" 27999 27999 'Fam3c' mRNA 4014 3861 3078 81.04 76.72 65.92 31.75 32.28 30.25 74.56 31.42666667 1809 1797 1669 3651 1758.333333 2.70E-41 -1.061023152 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0045721///negative regulation of gluconeogenesis 28000 28000 'Prpf19' mRNA 591 559 422 5.08 4.72 3.85 2.94 3.27 2.95 4.55 3.053333333 394 428 383 524 401.6666667 0.006175909 -0.388902337 03040///Spliceosome+++04120///Ubiquitin mediated proteolysis GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0035861///site of double-strand break+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000077///DNA damage checkpoint+++GO:0000209///protein polyubiquitination+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000245///spliceosomal complex assembly+++GO:0000349///generation of catalytic spliceosome for first transesterification step+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001833///inner cell mass cell proliferation+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008380///RNA splicing+++GO:0008610///lipid biosynthetic process+++GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0034613///cellular protein localization+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0070534///protein K63-linked ubiquitination+++GO:0072422///signal transduction involved in DNA damage checkpoint" 28006 28006 'Washc2' mRNA 1443 1507 1400 18.5 18.94 19.02 22.79 21.43 22.33 18.82 22.18333333 2032 1886 1948 1450 1955.333333 4.80E-09 0.419668114 04144///Endocytosis GO:0005730///nucleolus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071203///WASH complex "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1901981///phosphatidylinositol phosphate binding+++GO:1905394///retromer complex binding" "GO:0015031///protein transport+++GO:0036010///protein localization to endosome+++GO:0042147///retrograde transport, endosome to Golgi" 28010 28010 'Miip' mRNA 522 519 550 16.31 16.35 18.84 15.35 15.17 14.46 17.16666667 14.99333333 540 523 508 530.3333333 523.6666667 0.856890797 -0.032109849 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0030336///negative regulation of cell migration 28015 28015 'Polr2m' mRNA 6119 6009 5979 153.64 148.44 159.37 133.78 139.98 135.56 153.8166667 136.44 6124 6257 6011 6035.666667 6130.666667 0.892784784 0.010412481 03020///RNA polymerase "GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005665///RNA polymerase II, core complex+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0043025///neuronal cell body" GO:0003674///molecular_function+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity GO:0032774///RNA biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0051685///maintenance of ER location 28018 28018 'Ubfd1' mRNA 935 1019 369 10.51 11.42 4.33 5.61 6.26 7.83 8.753333333 6.566666667 583 639 792 774.3333333 671.3333333 0.748435514 -0.195286927 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 28019 28019 'Ing4' mRNA 2181 2188 2098 78.8 77.96 80.43 60.17 62.61 59.61 79.06333333 60.79666667 1913 1943 1834 2155.666667 1896.666667 0.007894558 -0.196113254 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding "GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006473///protein acetylation+++GO:0006915///apoptotic process+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0016573///histone acetylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043966///histone H3 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045926///negative regulation of growth+++GO:0051726///regulation of cell cycle" 28028 28028 'Mrpl50' mRNA 702 705 727 18.9 18.7 20.77 17.73 18.18 18.22 19.45666667 18.04333333 757 758 753 711.3333333 756 0.562203511 0.074860176 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function GO:0008150///biological_process 280287 280287 'Kiss1' mRNA 0 0 2 0 0 0.36 0 0 0 0.12 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 04080///Neuroactive ligand-receptor interaction+++04929///GnRH secretion GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0031773///kisspeptin receptor binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008285///negative regulation of cell proliferation+++GO:0030336///negative regulation of cell migration+++GO:0033686///positive regulation of luteinizing hormone secretion+++GO:0043410///positive regulation of MAPK cascade+++GO:0046697///decidualization+++GO:0050806///positive regulation of synaptic transmission+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060112///generation of ovulation cycle rhythm+++GO:0060124///positive regulation of growth hormone secretion 28030 28030 'Gfm1' mRNA 440 534 550 9.41 11.24 12.47 12.84 11.27 12.73 11.04 12.28 691 592 663 508 648.6666667 0.012839026 0.336812012 GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0070125///mitochondrial translational elongation 28035 28035 'Usp39' mRNA 573 588 584 14.54 14.75 15.68 17.64 15.95 17.03 14.99 16.87333333 797 707 740 581.6666667 748 0.001194258 0.349530092 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0016579///protein deubiquitination+++GO:0051301///cell division" 28036 28036 'Larp7' mRNA 539 551 538 14.38 14.48 15.23 17.12 16.28 17.31 14.69666667 16.90333333 738 685 722 542.6666667 715 3.24E-04 0.38542516 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0017070///U6 snRNA binding+++GO:0097322///7SK snRNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000494///box C/D snoRNA 3'-end processing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0007283///spermatogenesis+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0032897///negative regulation of viral transcription+++GO:0035562///negative regulation of chromatin binding+++GO:0036093///germ cell proliferation+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1905382///positive regulation of snRNA transcription by RNA polymerase II+++GO:1990438///U6 2'-O-snRNA methylation" 28040 28040 'D6Wsu163e' mRNA 375 385 342 9.38 9.53 9.08 10.46 9.47 9.37 9.33 9.766666667 485 423 417 367.3333333 441.6666667 0.065886847 0.254563285 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0043304///regulation of mast cell degranulation 280408 280408 'Rilp' mRNA 123 116 87 4.89 4.55 3.67 4.74 5.88 4.61 4.37 5.076666667 137 166 129 108.6666667 144 0.115507631 0.401218623 04145///Phagosome+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex+++GO:0036064///ciliary basal body GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0046983///protein dimerization activity+++GO:0051959///dynein light intermediate chain binding GO:0008333///endosome to lysosome transport+++GO:0010796///regulation of multivesicular body size+++GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0042177///negative regulation of protein catabolic process+++GO:0045022///early endosome to late endosome transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0060271///cilium assembly+++GO:0070676///intralumenal vesicle formation 280411 280411 'Lix1l' mRNA 47 43 39 1.04 0.94 0.92 1.93 1.88 1.81 0.966666667 1.873333333 100 95 91 43 95.33333333 1.42E-04 1.138346138 04391///Hippo signaling pathway - fly GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0097352///autophagosome maturation 28042 28042 'Selenoi' mRNA 1055 982 1029 8.19 7.5 8.48 4.34 3.42 4.12 8.056666667 3.96 643 496 592 1022 577 1.63E-14 -0.839705804 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process 280621 280621 'Selenov' mRNA 1 1 0 0.05 0.05 0 0.17 0.21 0.04 0.033333333 0.14 4 5 1 0.666666667 3.333333333 0.28650336 2.330544739 GO:0005829///cytosol GO:0003674///molecular_function GO:0010269///response to selenium ion 28064 28064 'Yipf3' mRNA 3107 3038 2763 99.53 97.03 94.43 104.24 99.18 97.82 96.99666667 100.4133333 3713 3444 3366 2969.333333 3507.666667 3.23E-04 0.229510051 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030154///cell differentiation 280645 280645 'B3gat2' mRNA 54.74 59.5 39.25 0.67 0.72 0.51 0.27 0.34 0.29 0.633333333 0.3 25.58 31.3 25.8 51.16333333 27.56 0.030731833 -0.911344017 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015018///galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0016051///carbohydrate biosynthetic process+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process 280667 280667 'Adam1b' mRNA 14.82 10.14 5.13 0.24 0.16 0.09 0.07 0.09 0.04 0.163333333 0.066666667 5.1 5.85 2.42 10.03 4.456666667 0.248581468 -1.271870257 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0007339///binding of sperm to zona pellucida+++GO:0008584///male gonad development 280668 280668 'Adam1a' mRNA 97.18 99.86 74.87 1.72 1.74 1.41 0.85 0.71 0.73 1.623333333 0.763333333 54.9 45.15 45.58 90.63666667 48.54333333 0.002895596 -0.914866346 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007339///binding of sperm to zona pellucida+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0008584///male gonad development 28071 28071 'Twistnb' mRNA 445 494 489 9.76 10.5 11.47 14.53 12.17 14.06 10.57666667 13.58666667 747 610 707 476 688 2.00E-05 0.516980046 03020///RNA polymerase GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0006352///DNA-templated transcription, initiation+++GO:1990830///cellular response to leukemia inhibitory factor" 28075 28075 'Desi1' mRNA 879 895 893 16.15 16.18 17.4 19.8 18.86 18.02 16.57666667 18.89333333 1240 1154 1093 889 1162.333333 5.45E-05 0.373557642 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0061676///importin-alpha family protein binding+++GO:0070140///SUMO-specific isopeptidase activity GO:0006508///proteolysis+++GO:0006611///protein export from nucleus+++GO:0016926///protein desumoylation+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0070646///protein modification by small protein removal 28077 28077 'Med10' mRNA 814 864 835 53.34 56.17 60.85 58.81 64.39 63.1 56.78666667 62.1 981 1042 1001 837.6666667 1008 0.009800467 0.255519626 GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II 28080 28080 'Atp5o' mRNA 4132 3904 4157 368.99 345.72 393.95 401.7 442.34 410.88 369.5533333 418.3066667 5147 5518 5082 4064.333333 5249 1.12E-06 0.355987786 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:1903924///estradiol binding" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process+++GO:0071320///cellular response to cAMP+++GO:0071345///cellular response to cytokine stimulus 28081 28081 'Fam104a' mRNA 1675.74 1664.02 1368.57 35.53 34.72 30.77 25.33 32.7 28.88 33.67333333 28.97 1374.07 1731.85 1516.1 1569.443333 1540.673333 0.825388239 -0.032287738 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 28084 28084 'Vps25' mRNA 2859 2931 2886 162.7 164.33 174.21 188.69 183.87 186.3 167.08 186.2866667 3784 3604 3621 2892 3669.666667 1.78E-07 0.330806627 04144///Endocytosis GO:0000814///ESCRT II complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0005198///structural molecule activity+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0015031///protein transport+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0071985///multivesicular body sorting pathway 28088 28088 'Rtcb' mRNA 2813 3076 3030 81.02 87.29 92.58 94.3 91.7 92 86.96333333 92.66666667 3764 3573 3554 2973 3630.333333 1.10E-04 0.274715244 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072669///tRNA-splicing ligase complex "GO:0000166///nucleotide binding+++GO:0003972///RNA ligase (ATP) activity+++GO:0005525///GTP binding+++GO:0008452///RNA ligase activity+++GO:0016874///ligase activity+++GO:0016886///ligase activity, forming phosphoric ester bonds+++GO:0017166///vinculin binding+++GO:0046872///metal ion binding" "GO:0000971///tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate+++GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006396///RNA processing+++GO:0008033///tRNA processing" 28105 28105 'Trim36' mRNA 2835.52 2754.41 2872.28 33.92 32.15 36.29 4.75 4.59 4.02 34.12 4.453333333 450.97 413.16 375.74 2820.736667 413.29 8.23E-216 -2.787084462 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0031410///cytoplasmic vesicle GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding GO:0000281///mitotic cytokinesis+++GO:0001578///microtubule bundle formation+++GO:0007051///spindle organization+++GO:0007340///acrosome reaction+++GO:0016567///protein ubiquitination+++GO:0051726///regulation of cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization 28106 28106 'Mydgf' mRNA 1689.81 1819.76 1611.86 121.17 129.16 122.65 176.67 187.35 173.93 124.3266667 179.3166667 2822.93 2916.9 2684.86 1707.143333 2808.23 4.12E-24 0.708246619 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus GO:0005125///cytokine activity+++GO:0030380///interleukin-17E receptor binding GO:0001525///angiogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0009620///response to fungus+++GO:0009624///response to nematode+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030222///eosinophil differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051897///positive regulation of protein kinase B signaling 28109 28109 'D10Wsu102e' mRNA 589 664 524 9.13 10.12 8.61 13.57 12.24 12.33 9.286666667 12.71333333 1008 888 887 592.3333333 927.6666667 8.13E-10 0.63772165 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0062064///box C/D snoRNP complex binding GO:0000492///box C/D snoRNP assembly 28113 28113 'Tinf2' mRNA 504 597 564 14.65 17.03 16.89 16.92 17.26 17.22 16.19 17.13333333 656.11 642 639 555 645.7033333 0.09994931 0.205759004 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0010370///perinucleolar chromocenter+++GO:0016604///nuclear body+++GO:0070187///shelterin complex" GO:0005515///protein binding+++GO:0042162///telomeric DNA binding "GO:0010836///negative regulation of protein ADP-ribosylation+++GO:0016233///telomere capping+++GO:0032202///telomere assembly+++GO:0032205///negative regulation of telomere maintenance+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0070198///protein localization to chromosome, telomeric region+++GO:1904356///regulation of telomere maintenance via telomere lengthening" 28114 28114 'Nsun2' mRNA 1505 1711 928 18.92 21.15 12.37 12.57 18.76 16.54 17.48 15.95666667 1151 1678 1467 1381.333333 1432 0.881313794 0.056986795 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0033391///chromatoid body+++GO:0070062///extracellular exosome GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016428///tRNA (cytosine-5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0001701///in utero embryonic development+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008033///tRNA processing+++GO:0010793///regulation of mRNA export from nucleus+++GO:0030154///cell differentiation+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0033313///meiotic cell cycle checkpoint+++GO:0036416///tRNA stabilization+++GO:0048820///hair follicle maturation+++GO:0051301///cell division+++GO:0080009///mRNA methylation+++GO:2000736///regulation of stem cell differentiation 28126 28126 'Nop16' mRNA 551 595 543 19.52 20.81 20.95 27.2 26.37 26.9 20.42666667 26.82333333 896 857 876 563 876.3333333 1.60E-10 0.627096827 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle GO:0042273///ribosomal large subunit biogenesis 28135 28135 'Cep63' mRNA 963.4 954.47 636.83 20.25 19.42 14.58 11.81 12.84 11.19 18.08333333 11.94666667 596.85 638.29 558.61 851.5666667 597.9166667 1.50E-04 -0.513458714 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0005515///protein binding GO:0000077///DNA damage checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007099///centriole replication+++GO:0007131///reciprocal meiotic recombination+++GO:0042770///signal transduction in response to DNA damage+++GO:0045141///meiotic telomere clustering+++GO:0051225///spindle assembly+++GO:0051298///centrosome duplication+++GO:0051301///cell division+++GO:0071539///protein localization to centrosome+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 28146 28146 'Serp1' mRNA 4742 4798 4955 107.98 107.57 119.69 214.8 218.45 216.47 111.7466667 216.5733333 10850 10775 10586 4831.666667 10737 1.05E-79 1.138434114 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001501///skeletal system development+++GO:0006006///glucose metabolic process+++GO:0006486///protein glycosylation+++GO:0009791///post-embryonic development+++GO:0010259///multicellular organism aging+++GO:0015031///protein transport+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032024///positive regulation of insulin secretion+++GO:0045727///positive regulation of translation+++GO:0046622///positive regulation of organ growth+++GO:0048644///muscle organ morphogenesis+++GO:0060124///positive regulation of growth hormone secretion 28169 28169 'Agpat3' mRNA 1009 1138 938 10.9 12.58 10.86 12.96 11.78 13.29 11.44666667 12.67666667 1206 1065 1239 1028.333333 1170 0.082102359 0.176348995 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04072///Phospholipase D signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042171///lysophosphatidic acid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process 28185 28185 'Tomm70a' mRNA 802 919 329 11.49 12.96 5 5.99 5.18 7.02 9.816666667 6.063333333 481 406 546 683.3333333 477.6666667 0.309812139 -0.508524476 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0005515///protein binding GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006626///protein targeting to mitochondrion+++GO:0032728///positive regulation of interferon-beta production+++GO:0042981///regulation of apoptotic process+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0098586///cellular response to virus+++GO:1904591///positive regulation of protein import 28193 28193 'Reep3' mRNA 1633.47 1653.88 1177.19 21.8 20.53 13.86 12.9 14.17 14.22 18.73 13.76333333 1314.19 1291 1336.01 1488.18 1313.733333 0.095055302 -0.184307296 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0008017///microtubule binding GO:0006998///nuclear envelope organization+++GO:0007049///cell cycle+++GO:0007084///mitotic nuclear envelope reassembly+++GO:0051301///cell division+++GO:0071786///endoplasmic reticulum tubular network organization 28199 28199 'Dcaf11' mRNA 3710 3892 3997 76.94 79.69 88.28 48.2 50.55 48.41 81.63666667 49.05333333 2647 2711 2563 3866.333333 2640.333333 8.08E-15 -0.563813109 GO:0005654///nucleoplasm+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 28200 28200 'Dhrs4' mRNA 966 924 960 42.93 40.73 45.88 35.57 37.13 38.13 43.18 36.94333333 879 898 901 950 892.6666667 0.360225674 -0.102435849 00830///Retinol metabolism+++04146///Peroxisome GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane "GO:0000253///3-keto sterol reductase activity+++GO:0001758///retinal dehydrogenase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018455///alcohol dehydrogenase [NAD(P)+] activity+++GO:0042802///identical protein binding" GO:0006066///alcohol metabolic process+++GO:0008202///steroid metabolic process+++GO:0042180///cellular ketone metabolic process+++GO:0042574///retinal metabolic process 28240 28240 'Trpm2' mRNA 281 268 250 3.44 3.27 3.13 2.9 2.66 2.77 3.28 2.776666667 237 244 231 266.3333333 237.3333333 0.333443136 -0.176641726 04621///NOD-like receptor signaling pathway+++04921///Oxytocin signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005272///sodium channel activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0015278///calcium-release channel activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047631///ADP-ribose diphosphatase activity+++GO:0072571///mono-ADP-D-ribose binding+++GO:0099604///ligand-gated calcium channel activity GO:0001659///temperature homeostasis+++GO:0002407///dendritic cell chemotaxis+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0006979///response to oxidative stress+++GO:0009408///response to heat+++GO:0014074///response to purine-containing compound+++GO:0032024///positive regulation of insulin secretion+++GO:0033194///response to hydroperoxide+++GO:0034220///ion transmembrane transport+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0035725///sodium ion transmembrane transport+++GO:0044849///estrous cycle+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051289///protein homotetramerization+++GO:0051489///regulation of filopodium assembly+++GO:0055085///transmembrane transport+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071415///cellular response to purine-containing compound+++GO:0071421///manganese ion transmembrane transport+++GO:0071502///cellular response to temperature stimulus+++GO:0071577///zinc ion transmembrane transport+++GO:0097028///dendritic cell differentiation+++GO:0097553///calcium ion transmembrane import into cytosol+++GO:0098655///cation transmembrane transport+++GO:0098703///calcium ion import across plasma membrane+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:2000249///regulation of actin cytoskeleton reorganization 28250 28250 'Slco1a4' mRNA 1056.49 1002 937 15.45 14.74 14.78 11.13 10.75 10.75 14.99 10.87666667 878 825.43 806.01 998.4966667 836.48 0.004705644 -0.266522406 04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0010468///regulation of gene expression+++GO:0015721///bile acid and bile salt transport+++GO:0035690///cellular response to drug+++GO:0038183///bile acid signaling pathway+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport+++GO:0120188///regulation of bile acid secretion+++GO:1904486///response to 17alpha-ethynylestradiol 28253 28253 'Slco1b2' mRNA 1 2 0 0.02 0.03 0 0.03 0 0 0.016666667 0.01 2 0 0 1 0.666666667 0.875524583 -0.586675233 04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0035673///oligopeptide transmembrane transporter activity GO:0001889///liver development+++GO:0006811///ion transport+++GO:0006857///oligopeptide transport+++GO:0015721///bile acid and bile salt transport+++GO:0032496///response to lipopolysaccharide+++GO:0033993///response to lipid+++GO:0034097///response to cytokine+++GO:0035672///oligopeptide transmembrane transport+++GO:0042493///response to drug+++GO:0043252///sodium-independent organic anion transport+++GO:0043434///response to peptide hormone+++GO:0046677///response to antibiotic+++GO:0051384///response to glucocorticoid+++GO:0055085///transmembrane transport 282619 282619 'Sbsn' mRNA 439 473 384 8.94 8.08 9 11.56 11.87 11.35 8.673333333 11.59333333 387 356 361 432 368 0.08484525 -0.240542173 GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 282663 282663 'Serpinb1b' mRNA 0 2 2 0 0.08 0.09 0.09 0.12 0.04 0.056666667 0.083333333 3 4 1 1.333333333 2.666666667 0.672959029 0.979383451 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0042176///regulation of protein catabolic process+++GO:0044342///type B pancreatic cell proliferation 28295 28295 'Gatd3a' mRNA 563 570 436 25.04 25.02 20.58 19.8 15.73 18.95 23.54666667 18.16 511 396 473 523 460 0.195873193 -0.19383868 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 286940 286940 'Flnb' mRNA 2647 2664 2466 15.3 15.14 15.13 13.21 12.65 12.93 15.19 12.93 2631 2462 2495 2592.333333 2529.333333 0.555884203 -0.046806944 04010///MAPK signaling pathway+++04510///Focal adhesion+++05132///Salmonella infection+++05205///Proteoglycans in cancer GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030018///Z disc+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045335///phagocytic vesicle GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0003334///keratinocyte development+++GO:0003382///epithelial cell morphogenesis+++GO:0007519///skeletal muscle tissue development+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0071346///cellular response to interferon-gamma 286942 286942 'Kif19a' mRNA 4071 3814 3070 64.56 59.51 51.65 27.74 21.14 23.5 58.57333333 24.12666667 2013 1498 1651 3651.666667 1720.666667 1.47E-30 -1.095129982 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0060404///axonemal microtubule depolymerization+++GO:0070462///plus-end specific microtubule depolymerization 29805 29805 'Znhit2' mRNA 682 699 697 32.87 33.26 35.64 26.45 26.91 27.44 33.92333333 26.93333333 630 625 632 692.6666667 629 0.196847055 -0.151590194 GO:0046872///metal ion binding 29806 29806 'Limd1' mRNA 1943 1946 1696 21.44 21.07 19.88 16.88 19.43 18.25 20.79666667 18.18666667 1760 1976 1849 1861.666667 1861.666667 0.940432724 -0.008245239 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016442///RISC complex+++GO:0030054///cell junction GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0001666///response to hypoxia+++GO:0002076///osteoblast development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0031047///gene silencing by RNA+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0035195///gene silencing by miRNA+++GO:0035331///negative regulation of hippo signaling+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000637///positive regulation of gene silencing by miRNA" 29807 29807 'Tpk1' mRNA 229 233 208 4.42 4.6 4.28 3.02 2.96 3.49 4.433333333 3.156666667 177 162 196 223.3333333 178.3333333 0.079871379 -0.335032423 00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0000166///nucleotide binding+++GO:0004788///thiamine diphosphokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030975///thiamine binding+++GO:0042802///identical protein binding GO:0006772///thiamine metabolic process+++GO:0009229///thiamine diphosphate biosynthetic process+++GO:0016310///phosphorylation 29808 29808 'Mga' mRNA 1375.72 1429.2 1370.36 4.63 4.68 4.91 3.72 3.32 3.35 4.74 3.463333333 1219.08 1103.01 1123.89 1391.76 1148.66 5.33E-04 -0.289572293 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0071339///MLL1 complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046983///protein dimerization activity" "GO:0001708///cell fate specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor" 29809 29809 'Rabgap1l' mRNA 2321 2415.87 2214.03 13.72 14.01 13.67 7.3 6.93 7.32 13.8 7.183333333 1204 1173.02 1164.84 2316.966667 1180.62 1.14E-45 -0.983883425 GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005929///cilium GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0032880///regulation of protein localization+++GO:0035855///megakaryocyte development+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity 29810 29810 'Bag3' mRNA 1022 913 861 21.87 19.24 19.55 21.43 23.3 20.51 20.22 21.74666667 1152 1223 1067 932 1147.333333 0.003954716 0.290082163 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0043005///neuron projection+++GO:0101031///chaperone complex GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding GO:0000045///autophagosome assembly+++GO:0006915///apoptotic process+++GO:0007420///brain development+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010664///negative regulation of striated muscle cell apoptotic process+++GO:0021510///spinal cord development+++GO:0034605///cellular response to heat+++GO:0034620///cellular response to unfolded protein+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0046716///muscle cell cellular homeostasis+++GO:0046827///positive regulation of protein export from nucleus+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0061684///chaperone-mediated autophagy+++GO:0071260///cellular response to mechanical stimulus+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:1903215///negative regulation of protein targeting to mitochondrion+++GO:1905337///positive regulation of aggrephagy 29811 29811 'Ndrg2' mRNA 12625 12956 12958 352.33 356.71 385.17 214.74 212.3 201.93 364.7366667 209.6566667 8822 8506 8024 12846.33333 8450.666667 4.19E-26 -0.617653442 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse GO:0001818///negative regulation of cytokine production+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090361///regulation of platelet-derived growth factor production+++GO:0099173///postsynapse organization 29812 29812 'Ndrg3' mRNA 4890 4910 5115 101.4 100.33 112.52 66.69 59.08 62.78 104.75 62.85 3675 3180 3339 4971.666667 3398 1.12E-15 -0.564149018 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007165///signal transduction 29813 29813 'Zfp385a' mRNA 2512 2405 672 59.52 55.61 17.16 11.95 13.98 13.22 44.09666667 13.05 586 665 623 1863 624.6666667 0.006584691 -1.561691751 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0002039///p53 binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007599///hemostasis+++GO:0007611///learning or memory+++GO:0007626///locomotory behavior+++GO:0008298///intracellular mRNA localization+++GO:0010609///mRNA localization resulting in posttranscriptional regulation of gene expression+++GO:0030220///platelet formation+++GO:0035855///megakaryocyte development+++GO:0045600///positive regulation of fat cell differentiation+++GO:0070889///platelet alpha granule organization+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000765///regulation of cytoplasmic translation" 29815 29815 'Bcar3' mRNA 636 571 589 10.89 9.67 10.9 9.63 10.2 9.87 10.48666667 9.9 657 684 660 598.6666667 667 0.249190878 0.144167098 GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction GO:0001784///phosphotyrosine residue binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019900///kinase binding GO:0002089///lens morphogenesis in camera-type eye+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043547///positive regulation of GTPase activity+++GO:0045740///positive regulation of DNA replication+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0086100///endothelin receptor signaling pathway 29816 29816 'Hip1r' mRNA 1771 1844 1812 21.69 22.21 23.54 11.81 10.38 10.69 22.48 10.96 1110 951 974 1809 1011.666667 1.19E-24 -0.852288408 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0032839///dendrite cytoplasm+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane "GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0017124///SH3 domain binding+++GO:0030276///clathrin binding+++GO:0032051///clathrin light chain binding+++GO:0035091///phosphatidylinositol binding+++GO:0035615///clathrin adaptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007015///actin filament organization+++GO:0030100///regulation of endocytosis+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032092///positive regulation of protein binding+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0048268///clathrin coat assembly+++GO:0050821///protein stabilization+++GO:0055123///digestive system development+++GO:0060453///regulation of gastric acid secretion+++GO:0061024///membrane organization+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1905445///positive regulation of clathrin coat assembly+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:2000370///positive regulation of clathrin-dependent endocytosis+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway 29817 29817 'Igfbp7' mRNA 1220 1347 233 67.84 74.01 13.72 47.5 55.95 80.57 51.85666667 61.34 981 1126 1607 933.3333333 1238 0.654729079 0.428690597 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005520///insulin-like growth factor binding+++GO:0019838///growth factor binding GO:0001558///regulation of cell growth+++GO:0007155///cell adhesion+++GO:0007566///embryo implantation+++GO:0009408///response to heat+++GO:0009966///regulation of signal transduction+++GO:0014070///response to organic cyclic compound+++GO:0032526///response to retinoic acid+++GO:0032870///cellular response to hormone stimulus+++GO:0048839///inner ear development+++GO:0050810///regulation of steroid biosynthetic process+++GO:0051414///response to cortisol 29818 29818 'Hspb7' mRNA 173 172 142 3.45 3.38 3.01 1.49 0.92 1.38 3.28 1.263333333 86 52 77 162.3333333 71.66666667 1.53E-06 -1.190909199 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0015030///Cajal body+++GO:0015629///actin cytoskeleton+++GO:0016235///aggresome GO:0031005///filamin binding GO:0007507///heart development+++GO:0009408///response to heat 29819 29819 'Stau2' mRNA 750.04 771.76 577.61 10.53 11.22 9.4 6.18 5.93 5.51 10.38333333 5.873333333 473.08 435.62 415 699.8033333 441.2333333 2.95E-08 -0.672330334 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005874///microtubule+++GO:0010494///cytoplasmic stress granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032839///dendrite cytoplasm+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:1990124///messenger ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0019894///kinesin binding+++GO:0030544///Hsp70 protein binding+++GO:0043022///ribosome binding+++GO:0051019///mitogen-activated protein kinase binding GO:0010468///regulation of gene expression+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0048592///eye morphogenesis+++GO:0051489///regulation of filopodium assembly+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0098964///anterograde dendritic transport of messenger ribonucleoprotein complex+++GO:1900454///positive regulation of long-term synaptic depression 29820 29820 'Tnfrsf19' mRNA 1927 1965 1808 22.98 23.25 22.55 23.56 24.43 24.97 22.92666667 24.32 2223 2255 2302 1900 2260 6.66E-04 0.23985739 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0001942///hair follicle development+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade 29856 29856 'Smtn' mRNA 2992 2843 2744 49.06 45.9 47.83 44.5 43.1 42.6 47.59666667 43.4 3122 2956 2892 2859.666667 2990 0.5098098 0.052529715 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0031941///filamentous actin GO:0003779///actin binding GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0030036///actin cytoskeleton organization+++GO:0060452///positive regulation of cardiac muscle contraction 29857 29857 'Mapk12' mRNA 337 432 188 11.02 14.28 7.29 4.32 8.25 6.69 10.86333333 6.42 137 274 225 319 212 0.258105107 -0.57798882 "01522///Endocrine resistance+++04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04068///FoxO signaling pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04212///Longevity regulating pathway - worm+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04660///T cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04917///Prolactin signaling pathway+++04926///Relaxin signaling pathway+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05135///Yersinia infection+++05140///Leishmaniasis+++05142///Chagas disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05205///Proteoglycans in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0045445///myoblast differentiation+++GO:0045786///negative regulation of cell cycle 29858 29858 'Pmm1' mRNA 1618 1642 1574 75.16 75.29 77.58 51.79 55.92 50.71 76.01 52.80666667 1280 1348 1212 1611.333333 1280 3.34E-05 -0.343399878 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body GO:0004615///phosphomannomutase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0006013///mannose metabolic process+++GO:0006487///protein N-linked glycosylation+++GO:0009298///GDP-mannose biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 29859 29859 'Sult4a1' mRNA 507 516 470 11.28 11.32 11.05 1.35 1.55 0.86 11.21666667 1.253333333 70 78 43 497.6666667 63.66666667 4.64E-57 -2.977123676 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006629///lipid metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0008202///steroid metabolic process+++GO:0051923///sulfation+++GO:0140059///dendrite arborization 29861 29861 'Dpf1' mRNA 66.92 58.8 45.69 1.67 1.44 1.21 0.33 0.51 0.54 1.44 0.46 15.7 23 24 57.13666667 20.9 6.35E-04 -1.449934058 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071565///nBAF complex GO:0003712///transcription coregulator activity+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0007399///nervous system development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 29862 29862 'Ninj2' mRNA 175 150 149 14.31 12.21 12.99 5.53 3.97 3.61 13.17 4.37 77 54 51 158 60.66666667 3.14E-08 -1.394863314 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007155///cell adhesion+++GO:0042246///tissue regeneration 29863 29863 'Pde7b' mRNA 145 149 89 1.52 1.54 0.99 1.95 1.37 1.86 1.35 1.726666667 214 147 197 127.6666667 186 0.02873166 0.537570479 00230///Purine metabolism+++05032///Morphine addiction "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0019933///cAMP-mediated signaling 29864 29864 'Rnf11' mRNA 349 311 323 9.26 8.13 9.09 7.73 6.57 8.27 8.826666667 7.523333333 335 278 347 327.6666667 320 0.82482207 -0.047503891 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination 29866 29866 'Cabp2' mRNA 9087 9164 8868 572.33 572.29 591.31 57.96 58.33 60.61 578.6433333 58.96666667 1053 1045 1059 9039.666667 1052.333333 0 -3.114659957 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0050896///response to stimulus 29867 29867 'Cabp1' mRNA 25 20 21 1.6 1.14 1.42 0.39 0.34 0.29 1.386666667 0.34 7 6 5 22 6 0.007396197 -1.887345245 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0044280///subplasmalemmal coating+++GO:0048471///perinuclear region of cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099573///glutamatergic postsynaptic density GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0019904///protein domain specific binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0007601///visual perception+++GO:0010651///negative regulation of cell communication by electrical coupling+++GO:0042308///negative regulation of protein import into nucleus+++GO:0050896///response to stimulus+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1905539///regulation of postsynapse to nucleus signaling pathway 29869 29869 'Ulk2' mRNA 861 892 564 7.74 7.92 5.38 3.49 3.52 4.58 7.013333333 3.863333333 449 435 565 772.3333333 483 8.78E-06 -0.679203655 04136///Autophagy - other+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04212///Longevity regulating pathway - worm+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034045///phagophore assembly site membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006468///protein phosphorylation+++GO:0006914///autophagy+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0010508///positive regulation of autophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0042594///response to starvation+++GO:0044805///late nucleophagy+++GO:0046777///protein autophosphorylation+++GO:0048671///negative regulation of collateral sprouting+++GO:0048675///axon extension+++GO:0061709///reticulophagy+++GO:0075044///autophagy of host cells involved in interaction with symbiont 29870 29870 'Gtse1' mRNA 5 8 5 0.1 0.16 0.11 4.88 5.13 4.46 0.123333333 4.823333333 273 280 243 6 265.3333333 3.66E-43 5.45705276 04115///p53 signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton GO:0008017///microtubule binding 29871 29871 'Scmh1' mRNA 1446.79 1470.02 1352.73 19.09 20.06 19.44 15.15 13.41 15.11 19.53 14.55666667 1328.28 1145.38 1260.32 1423.18 1244.66 0.016642659 -0.205051655 GO:0005634///nucleus+++GO:0010369///chromocenter GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding "GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0016458///gene silencing+++GO:0045892///negative regulation of transcription, DNA-templated" 29873 29873 'Cspg5' mRNA 350 346 314 4.98 4.86 4.74 2.88 2.94 3.4 4.86 3.073333333 233 232 266 336.6666667 243.6666667 0.00201172 -0.47636235 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030660///Golgi-associated vesicle membrane+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane "GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0040008///regulation of growth+++GO:0048858///cell projection morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0099550///trans-synaptic signaling, modulating synaptic transmission+++GO:0106091///glial cell projection elongation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:2000300///regulation of synaptic vesicle exocytosis" 29875 29875 'Iqgap1' mRNA 5032 5039 4943 36.06 35.49 37.57 67 59.57 64.9 36.37333333 63.82333333 10768 9355 10105 5004.666667 10076 5.08E-66 0.996168039 04520///Adherens junction+++04810///Regulation of actin cytoskeleton+++05205///Proteoglycans in cancer GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0030864///cortical actin cytoskeleton+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:1990904///ribonucleoprotein complex "GO:0005078///MAP-kinase scaffold activity+++GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0031267///small GTPase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0044548///S100 protein binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0060090///molecular adaptor activity" GO:0001817///regulation of cytokine production+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007346///regulation of mitotic cell cycle+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010761///fibroblast migration+++GO:0016477///cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035305///negative regulation of dephosphorylation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0043087///regulation of GTPase activity+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045860///positive regulation of protein kinase activity+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0071277///cellular response to calcium ion+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072015///glomerular visceral epithelial cell development+++GO:1900006///positive regulation of dendrite development+++GO:1900086///positive regulation of peptidyl-tyrosine autophosphorylation+++GO:1903829///positive regulation of cellular protein localization+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:1990138///neuron projection extension+++GO:1990776///response to angiotensin 29876 29876 'Clic4' mRNA 2329 2257 2232 30.9 29.45 31.41 58.53 59.16 56.95 30.58666667 58.21333333 5078 5014 4785 2272.666667 4959 3.39E-74 1.113590806 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0030496///midbody+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034707///chloride channel complex+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007035///vacuolar acidification+++GO:0009566///fertilization+++GO:0030216///keratinocyte differentiation+++GO:0030336///negative regulation of cell migration+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035264///multicellular organism growth+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0071277///cellular response to calcium ion 29877 29877 'Hdgfl3' mRNA 533.79 535.48 377.42 4.83 4.77 3.63 3.11 3.01 3.47 4.41 3.196666667 394.3 373.14 426.98 482.23 398.14 0.065134436 -0.281606065 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008083///growth factor activity+++GO:0015631///tubulin binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007165///signal transduction+++GO:0031175///neuron projection development+++GO:0046785///microtubule polymerization 30044 30044 'Opn4' mRNA 24 23 14 0.61 0.57 0.37 0.22 0.02 0.02 0.516666667 0.086666667 10 1 1 20.33333333 4 0.008988945 -2.362344978 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:1990913///sperm head plasma membrane GO:0004930///G protein-coupled receptor activity+++GO:0005502///11-cis retinal binding+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0007634///optokinetic behavior+++GO:0009416///response to light stimulus+++GO:0009584///detection of visible light+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0018298///protein-chromophore linkage+++GO:0042752///regulation of circadian rhythm+++GO:0043052///thermotaxis+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045938///positive regulation of circadian sleep/wake cycle, sleep+++GO:0048511///rhythmic process+++GO:0050896///response to stimulus+++GO:0050960///detection of temperature stimulus involved in thermoception+++GO:0071482///cellular response to light stimulus+++GO:1990384///hyaloid vascular plexus regression" 30045 30045 'Dnajc12' mRNA 287 286 292 13.49 13.27 14.56 8.84 10.12 7.79 13.77333333 8.916666667 216 241 182 288.3333333 213 0.011514888 -0.449174068 GO:0005737///cytoplasm GO:0008150///biological_process 30046 30046 'Zfp292' mRNA 1329 1410 1184 7.73 7.82 7.15 3.75 4.07 4.26 7.566666667 4.026666667 825 824 869 1307.666667 839.3333333 7.10E-14 -0.64855177 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 30049 30049 'Scd3' mRNA 106.92 117.84 151 1.68 1.82 2.51 2.76 2.47 3.35 2.003333333 2.86 202.42 177.04 237.88 125.2533333 205.78 0.002331807 0.700768381 01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04212///Longevity regulating pathway - worm+++04936///Alcoholic liver disease GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0032896///palmitoyl-CoA 9-desaturase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0070542///response to fatty acid+++GO:1903966///monounsaturated fatty acid biosynthetic process 30050 30050 'Fbxw2' mRNA 1370 1392 1250 31.92 31.5 30.21 31.37 28.53 32.27 31.21 30.72333333 1541 1362 1533 1337.333333 1478.666667 0.130394233 0.133918662 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding 30051 30051 'Spdef' mRNA 21.98 15 8.31 0.49 0.43 0.21 0.42 0.36 0.19 0.376666667 0.323333333 14.99 14.09 9 15.09666667 12.69333333 0.791143807 -0.249855353 04361///Axon regeneration GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010454///negative regulation of cell fate commitment+++GO:0010455///positive regulation of cell fate commitment+++GO:0030154///cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060480///lung goblet cell differentiation+++GO:0060576///intestinal epithelial cell development" 30052 30052 'Pcsk1n' mRNA 89 84 94 2.29 2.13 2.56 0.72 0.39 0.37 2.326666667 0.493333333 32 17 16 89 21.66666667 2.61E-08 -2.057615501 GO:0000932///P-body+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0030141///secretory granule+++GO:0031251///PAN complex GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0004672///protein kinase activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding "GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0002021///response to dietary excess+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006605///protein targeting+++GO:0007218///neuropeptide signaling pathway+++GO:0009409///response to cold+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016486///peptide hormone processing+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 30053 30053 'Reg3d' mRNA 0 1 0 0 0.11 0 0 0 0 0.036666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005615///extracellular space GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0042834///peptidoglycan binding+++GO:0070492///oligosaccharide binding GO:0008284///positive regulation of cell proliferation+++GO:0043434///response to peptide hormone+++GO:0044278///cell wall disruption in other organism+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 30054 30054 'Rnf17' mRNA 41 27 32 0.5 0.35 0.42 0.08 0.11 0.07 0.423333333 0.086666667 8 9 6 33.33333333 7.666666667 3.22E-04 -2.13242821 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation 30055 30055 'Timm13' mRNA 1836 1689 1814 91.68 83.28 96.11 100.16 115.23 101.33 90.35666667 105.5733333 2302 2583 2252 1779.666667 2379 4.74E-06 0.406230197 GO:0001650///fibrillar center+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0042719///mitochondrial intermembrane space protein transporter complex GO:0032977///membrane insertase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0072321///chaperone-mediated protein transport 30056 30056 'Timm9' mRNA 374 383 355 27.3 27.54 27.7 23.74 19.93 23.31 27.51333333 22.32666667 372 306 355 370.6666667 344.3333333 0.479206595 -0.118588606 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0042719///mitochondrial intermembrane space protein transporter complex GO:0032977///membrane insertase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0072321///chaperone-mediated protein transport 30057 30057 'Timm8b' mRNA 998 1014 1114 155.32 157.63 184.07 155.47 191.86 159.11 165.6733333 168.8133333 1137 1362 1120 1042 1206.333333 0.107231825 0.197829893 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0072321///chaperone-mediated protein transport 30058 30058 'Timm8a1' mRNA 356 397 397 17.76 19.56 21.01 26.3 27.19 22.25 19.44333333 25.24666667 605 610 495 383.3333333 570 3.94E-05 0.558915356 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006626///protein targeting to mitochondrion+++GO:0015031///protein transport+++GO:0072321///chaperone-mediated protein transport 30059 30059 'Timm10' mRNA 355 379 310 38.87 41.24 36.03 57.79 54.49 52.57 38.71333333 54.95 603 553 529 348 561.6666667 3.22E-08 0.681004383 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0042719///mitochondrial intermembrane space protein transporter complex GO:0032977///membrane insertase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0072321///chaperone-mediated protein transport 30060 30060 'Meltf' mRNA 3928 4200 4030 51.18 53.8 55.7 31.36 29.18 30.51 53.56 30.35 2771 2519 2615 4052.666667 2635 4.28E-23 -0.634054474 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane+++GO:0055037///recycling endosome GO:0005506///iron ion binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0010756///positive regulation of plasminogen activation+++GO:0055072///iron ion homeostasis+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading 30785 30785 'Cttnbp2' mRNA 536 511 476 4.76 4.46 4.49 2.78 2.45 2.47 4.57 2.566666667 361 310 310 507.6666667 327 4.19E-07 -0.646342279 GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0008021///synaptic vesicle+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse GO:0005519///cytoskeletal regulatory protein binding+++GO:0017124///SH3 domain binding GO:0007420///brain development+++GO:0030036///actin cytoskeleton organization+++GO:0050807///regulation of synapse organization+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton 30791 30791 'Slc39a1' mRNA 5282 4356 5292 126.14 102.43 134.03 230.6 231.51 224.85 120.8666667 228.9866667 11104 10880 10481 4976.666667 10821.66667 4.46E-41 1.104624262 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0001701///in utero embryonic development+++GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0030001///metal ion transport+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0055085///transmembrane transport+++GO:0060173///limb development+++GO:0071577///zinc ion transmembrane transport 30794 30794 'Pdlim4' mRNA 438 404 389 23.08 21.7 22.01 43.64 41.46 41.19 22.26333333 42.09666667 914 850 855 410.3333333 873 2.59E-25 1.07771223 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031901///early endosome membrane+++GO:0031905///early endosome lumen+++GO:0031941///filamentous actin+++GO:0034777///recycling endosome lumen+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding+++GO:0042803///protein homodimerization activity+++GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding+++GO:0051393///alpha-actinin binding GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0061061///muscle structure development+++GO:0098976///excitatory chemical synaptic transmission 30795 30795 'Fkbp3' mRNA 1488.56 1419.9 1450.22 102.17 96.43 105.62 100.29 101.69 102.06 101.4066667 101.3466667 1674.53 1654.64 1646.52 1452.893333 1658.563333 0.032042331 0.178497218 GO:0005634///nucleus GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization 30805 30805 'Slc22a4' mRNA 306 354 291 6.5 7.11 6.45 6.31 6.1 6.09 6.686666667 6.166666667 333 308 310 317 317 0.961746995 -0.009941697 05231///Choline metabolism in cancer GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015226///carnitine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015491///cation:cation antiporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding GO:0006641///triglyceride metabolic process+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0009437///carnitine metabolic process+++GO:0015697///quaternary ammonium group transport+++GO:0015879///carnitine transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:0098655///cation transmembrane transport+++GO:1902603///carnitine transmembrane transport 30806 30806 'Adamts8' mRNA 48 33 26 0.56 0.38 0.32 0.37 0.29 0.27 0.42 0.31 37 28 26 35.66666667 30.33333333 0.678634785 -0.241222519 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0030198///extracellular matrix organization 30838 30838 'Fbxw4' mRNA 161 178 142 4.34 4.86 3.95 10.36 9.61 10.93 4.383333333 10.3 424 378 423 160.3333333 408.3333333 1.05E-18 1.339162943 GO:0019005///SCF ubiquitin ligase complex GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0042733///embryonic digit morphogenesis+++GO:0051216///cartilage development+++GO:0060173///limb development 30839 30839 'Fbxw5' mRNA 2252 2182 2132 52.83 50.35 53.1 39.83 38.7 40.49 52.09333333 39.67333333 1953 1853 1921 2188.666667 1909 0.003505322 -0.209275312 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0007088///regulation of mitotic nuclear division+++GO:0010824///regulation of centrosome duplication+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 30840 30840 'Fbxl6' mRNA 682 701 606 23 23.3 21.68 23.71 25.26 23.81 22.66 24.26 808 840 785 663 811 0.006777972 0.281477946 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0000086///G2/M transition of mitotic cell cycle+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0051726///regulation of cell cycle 30841 30841 'Kdm2b' mRNA 387 372 356 4.87 4.85 4.55 5.69 5.64 5.8 4.756666667 5.71 490 489 488 371.6666667 489 0.002288306 0.384797985 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0031519///PcG protein complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0019843///rRNA binding+++GO:0032452///histone demethylase activity+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific) GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0007283///spermatogenesis+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0021592///fourth ventricle development+++GO:0021670///lateral ventricle development+++GO:0021678///third ventricle development+++GO:0021993///initiation of neural tube closure+++GO:0030307///positive regulation of cell growth+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0035518///histone H2A monoubiquitination+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0070544///histone H3-K36 demethylation+++GO:1902459///positive regulation of stem cell population maintenance+++GO:2000178///negative regulation of neural precursor cell proliferation 30843 30843 'Fbxl12' mRNA 577.64 546.04 530.26 14.05 13.21 14.44 9.46 8.85 8.65 13.9 8.986666667 409.47 388.2 376.98 551.3133333 391.55 2.38E-05 -0.506645524 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0051726///regulation of cell cycle 30853 30853 'Mlf2' mRNA 6924 7022 4411 267.78 267.88 180.99 158 230.06 206.9 238.8833333 198.32 4693 6667 5945 6119 5768.333333 0.817447398 -0.082721622 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated" 30877 30877 'Gnl3' mRNA 311 304 316 9.23 8.89 9.95 17.64 17.09 17.34 9.356666667 17.35666667 683 646 650 310.3333333 659.6666667 6.93E-20 1.074791682 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0030496///midbody GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0048027///mRNA 5'-UTR binding "GO:0008283///cell proliferation+++GO:0017145///stem cell division+++GO:0019827///stem cell population maintenance+++GO:0032206///positive regulation of telomere maintenance+++GO:0033235///positive regulation of protein sumoylation+++GO:0042127///regulation of cell proliferation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904816///positive regulation of protein localization to chromosome, telomeric region" 30878 30878 'Apln' mRNA 128 159 146 2.23 2.72 2.69 4.17 4.69 4.7 2.546666667 4.52 276 303 301 144.3333333 293.3333333 9.52E-09 1.012161566 04080///Neuroactive ligand-receptor interaction+++04371///Apelin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0031704///apelin receptor binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0002026///regulation of the force of heart contraction+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0007631///feeding behavior+++GO:0008284///positive regulation of cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0010629///negative regulation of gene expression+++GO:0031652///positive regulation of heat generation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0042327///positive regulation of phosphorylation+++GO:0042756///drinking behavior+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0045776///negative regulation of blood pressure+++GO:0045823///positive regulation of heart contraction+++GO:0045906///negative regulation of vasoconstriction+++GO:0050878///regulation of body fluid levels+++GO:0051461///positive regulation of corticotropin secretion+++GO:0051466///positive regulation of corticotropin-releasing hormone secretion+++GO:0060183///apelin receptor signaling pathway+++GO:0060976///coronary vasculature development+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904022///positive regulation of G protein-coupled receptor internalization+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905564///positive regulation of vascular endothelial cell proliferation 30923 30923 'Foxe3' mRNA 1 0 1 0.04 0 0.04 0.03 0.06 0 0.026666667 0.03 1 2 0 0.666666667 1 0.871033026 0.55995991 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001654///eye development+++GO:0002088///lens development in camera-type eye+++GO:0002930///trabecular meshwork development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0043010///camera-type eye development+++GO:0043066///negative regulation of apoptotic process+++GO:0048468///cell development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0061072///iris morphogenesis+++GO:0061073///ciliary body morphogenesis+++GO:0061303///cornea development in camera-type eye+++GO:0071157///negative regulation of cell cycle arrest+++GO:1902747///negative regulation of lens fiber cell differentiation+++GO:2001111///positive regulation of lens epithelial cell proliferation" 30924 30924 'Angptl3' mRNA 4 8 8 0.15 0.29 0.31 0.32 0.06 0.23 0.25 0.203333333 10 2 7 6.666666667 6.333333333 0.940562705 -0.100214358 04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0062023///collagen-containing extracellular matrix GO:0004857///enzyme inhibitor activity+++GO:0004859///phospholipase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding GO:0001525///angiogenesis+++GO:0006071///glycerol metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007165///signal transduction+++GO:0008203///cholesterol metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0009725///response to hormone+++GO:0010519///negative regulation of phospholipase activity+++GO:0019915///lipid storage+++GO:0030335///positive regulation of cell migration+++GO:0042632///cholesterol homeostasis+++GO:0045766///positive regulation of angiogenesis+++GO:0045834///positive regulation of lipid metabolic process+++GO:0048844///artery morphogenesis+++GO:0050996///positive regulation of lipid catabolic process+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0055088///lipid homeostasis+++GO:0055090///acylglycerol homeostasis+++GO:0055091///phospholipid homeostasis+++GO:0070328///triglyceride homeostasis 30925 30925 'Slamf6' mRNA 12 12 6 0.38 0.39 0.17 2.29 3.29 2.16 0.313333333 2.58 88 113 76 10 92.33333333 4.77E-14 3.203826653 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001779///natural killer cell differentiation+++GO:0001787///natural killer cell proliferation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0042110///T cell activation+++GO:0045087///innate immune response+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0072540///T-helper 17 cell lineage commitment 30926 30926 'Glrx3' mRNA 1505 1556 1390 30.07 30.59 29.47 42.97 45.17 41.17 30.04333333 43.10333333 2472 2539 2293 1483.666667 2434.666667 3.32E-22 0.704514227 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005938///cell cortex+++GO:0030018///Z disc+++GO:0030425///dendrite GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0097573///glutathione oxidoreductase activity GO:0002026///regulation of the force of heart contraction+++GO:0006879///cellular iron ion homeostasis+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer 30927 30927 'Snai3' mRNA 3 10 9 0.11 0.37 0.35 0.35 0.26 0.27 0.276666667 0.293333333 11 8 8 7.333333333 9 0.822623916 0.276164748 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 30928 30928 'Zbtb18' mRNA 212 199 194 2.92 2.71 2.84 2.23 2.18 1.87 2.823333333 2.093333333 189 180 146 201.6666667 171.6666667 0.253600686 -0.244446848 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007519///skeletal muscle tissue development+++GO:0021549///cerebellum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048666///neuron development+++GO:0048872///homeostasis of number of cells+++GO:0051302///regulation of cell division" 30930 30930 'Vps26a' mRNA 1321 1423 1446 24 25.4 27.78 37.18 38.97 40.78 25.72666667 38.97666667 2360 2417 2505 1396.666667 2427.333333 2.32E-22 0.784344241 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0030906///retromer, cargo-selective complex+++GO:0031982///vesicle+++GO:0097422///tubular endosome" GO:0005515///protein binding "GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi" 30931 30931 'Tor1a' mRNA 704.64 672.72 651.7 28.82 27.14 28.28 32.61 31.49 32.46 28.08 32.18666667 915.65 862.7 881.88 676.3533333 886.7433333 9.34E-05 0.379274596 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0030141///secretory granule+++GO:0030426///growth cone+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding "GO:0000338///protein deneddylation+++GO:0006979///response to oxidative stress+++GO:0006996///organelle organization+++GO:0006998///nuclear envelope organization+++GO:0007155///cell adhesion+++GO:0031175///neuron projection development+++GO:0034504///protein localization to nucleus+++GO:0044319///wound healing, spreading of cells+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0048489///synaptic vesicle transport+++GO:0048499///synaptic vesicle membrane organization+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051584///regulation of dopamine uptake involved in synaptic transmission+++GO:0061077///chaperone-mediated protein folding+++GO:0061992///ATP-dependent chaperone mediated protein folding+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0071763///nuclear membrane organization+++GO:0072321///chaperone-mediated protein transport+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:2000008///regulation of protein localization to cell surface" 30932 30932 'Zfp330' mRNA 768 917 805 26.92 31.67 29.91 29.99 28.4 29.1 29.5 29.16333333 983 906 922 830 937 0.133038596 0.163392613 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030496///midbody" GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 30933 30933 'Tor2a' mRNA 766.98 789.96 749.95 27.8 27.83 28.68 35.18 34.79 37.21 28.10333333 35.72666667 1086.77 1053.93 1109.92 768.9633333 1083.54 7.17E-08 0.483871125 GO:0005576///extracellular region+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0000166///nucleotide binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0051085///chaperone cofactor-dependent protein refolding 30934 30934 'Tor1b' mRNA 1088.36 1005.28 1046.3 20.27 18.44 20.66 23.61 20.88 22.49 19.79 22.32666667 1460.35 1262.3 1357.12 1046.646667 1359.923333 5.96E-05 0.364066612 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:0042802///identical protein binding GO:0007029///endoplasmic reticulum organization+++GO:0034504///protein localization to nucleus+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071763///nuclear membrane organization 30935 30935 'Tor3a' mRNA 981 845 910 16.39 13.89 16.13 29.19 30.04 29.74 15.47 29.65666667 2010 2020 1983 912 2004.333333 6.89E-40 1.123416515 GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity 30936 30936 'Slc46a2' mRNA 39 33 38 1.07 0.9 1.11 0.05 0.15 0.15 1.026666667 0.116666667 2 6 6 36.66666667 4.666666667 3.37E-06 -2.984284734 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0043029///T cell homeostasis+++GO:0045580///regulation of T cell differentiation+++GO:0048538///thymus development+++GO:0055085///transmembrane transport+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0070430///positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway 30937 30937 'Lmcd1' mRNA 117 160 118 4.03 5.29 4.22 5.98 6.51 5.31 4.513333333 5.933333333 205 216 176 131.6666667 199 0.006217341 0.587837121 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010611///regulation of cardiac muscle hypertrophy+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 30938 30938 'Fgd3' mRNA 20 18 27 0.25 0.24 0.32 1.12 1.23 1.54 0.27 1.296666667 89 92 119 21.66666667 100 4.87E-10 2.190007558 04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding GO:0007010///cytoskeleton organization+++GO:0046847///filopodium assembly+++GO:0050790///regulation of catalytic activity 30939 30939 'Pttg1' mRNA 394 407 459 32.32 32.65 41.45 45.65 48.7 44.98 35.47333333 46.44333333 600 646 577 420 607.6666667 8.81E-05 0.518194471 04110///Cell cycle+++04114///Oocyte meiosis+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0017124///SH3 domain binding+++GO:0031072///heat shock protein binding+++GO:0043022///ribosome binding GO:0001558///regulation of cell growth+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008285///negative regulation of cell proliferation+++GO:0009987///cellular process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0045143///homologous chromosome segregation+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:2000816///negative regulation of mitotic sister chromatid separation 30940 30940 'Usp25' mRNA 955 959 776 11.48 11.44 10.04 9.34 7.76 8.2 10.98666667 8.433333333 885 714 748 896.6666667 782.3333333 0.073411781 -0.206503303 04657///IL-17 signaling pathway GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0032183///SUMO binding+++GO:0051117///ATPase binding GO:0001816///cytokine production+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006955///immune response+++GO:0006979///response to oxidative stress+++GO:0007252///I-kappaB phosphorylation+++GO:0016071///mRNA metabolic process+++GO:0016579///protein deubiquitination+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032602///chemokine production+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:1904293///negative regulation of ERAD pathway 30941 30941 'Usp21' mRNA 1220 1181 1090 31.5 30.03 29.85 26.67 27.89 24.31 30.46 26.29 1188 1213 1048 1163.666667 1149.666667 0.831488659 -0.027867251 04217///Necroptosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003713///transcription coactivator activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019784///NEDD8-specific protease activity+++GO:0042393///histone binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding "GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0031175///neuron projection development+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045901///positive regulation of translational elongation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051289///protein homotetramerization+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0140014///mitotic nuclear division" 30942 30942 'Hnf4g' mRNA 7 13 11 0.09 0.16 0.15 0.03 0.03 0.03 0.133333333 0.03 3 3 3 10.33333333 3 0.089435926 -1.797142967 04950///Maturity onset diabetes of the young GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development" 30944 30944 'Zfp354c' mRNA 478 436 401 4.74 4.26 4.22 2.65 2.45 2.43 4.406666667 2.51 307 278 273 438.3333333 286 4.37E-06 -0.626724098 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 30945 30945 'Rnf19a' mRNA 776 835 752 9.78 10.35 10.04 12.5 10.54 10.29 10.05666667 11.11 1144 939 912 787.6666667 998.3333333 0.002013096 0.329268916 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission" 30946 30946 'Abt1' mRNA 479 449.02 471 5.77 5.32 6.02 5.72 6.19 5.6 5.703333333 5.836666667 546.13 577.91 518.04 466.34 547.36 0.099513512 0.217726182 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021522///spinal cord motor neuron differentiation+++GO:0034462///small-subunit processome assembly" 30947 30947 'Adat1' mRNA 554.49 532.4 459.54 9.2 8.9 8.41 5.56 5.16 5.35 8.836666667 5.356666667 376.77 332.63 363.53 515.4766667 357.6433333 2.03E-05 -0.538429342 GO:0005575///cellular_component GO:0003723///RNA binding+++GO:0004000///adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006396///RNA processing+++GO:0008033///tRNA processing 30948 30948 'Bin1' mRNA 934 933 865 24.8 24.77 24.55 44.51 42.21 43.42 24.70666667 43.38 1831 1686 1718 910.6666667 1745 1.03E-33 0.926825316 04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031674///I band+++GO:0031982///vesicle+++GO:0033268///node of Ranvier+++GO:0043194///axon initial segment+++GO:0043196///varicosity+++GO:0043679///axon terminus+++GO:0044300///cerebellar mossy fiber+++GO:0045202///synapse+++GO:0060987///lipid tube+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:0098978///glutamatergic synapse GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0048156///tau protein binding+++GO:0051015///actin filament binding+++GO:0051020///GTPase binding+++GO:0051087///chaperone binding+++GO:0070063///RNA polymerase binding GO:0006897///endocytosis+++GO:0006997///nucleus organization+++GO:0007275///multicellular organism development+++GO:0008333///endosome to lysosome transport+++GO:0030100///regulation of endocytosis+++GO:0030154///cell differentiation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033292///T-tubule organization+++GO:0042692///muscle cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0045664///regulation of neuron differentiation+++GO:0045807///positive regulation of endocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0051647///nucleus localization+++GO:0051726///regulation of cell cycle+++GO:0060988///lipid tube assembly+++GO:0071156///regulation of cell cycle arrest+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902960///negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:1903946///negative regulation of ventricular cardiac muscle cell action potential+++GO:1904878///negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 30949 30949 'Lcmt1' mRNA 717 679 568 31.33 29.2 26.4 26.93 25.53 28.55 28.97666667 27.00333333 706 653 724 654.6666667 694.3333333 0.580961302 0.076234609 GO:0005829///cytosol GO:0003880///protein C-terminal carboxyl O-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0018423///protein C-terminal leucine carboxyl O-methyltransferase activity GO:0006479///protein methylation+++GO:0006481///C-terminal protein methylation+++GO:0010906///regulation of glucose metabolic process+++GO:0031333///negative regulation of protein complex assembly+++GO:0032259///methylation+++GO:0042981///regulation of apoptotic process+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint 30951 30951 'Cbx8' mRNA 205 217 236 8.8 9.19 10.75 8.86 6.82 6.57 9.58 7.416666667 237 178 170 219.3333333 195 0.414278549 -0.187157175 GO:0000151///ubiquitin ligase complex+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0097027///ubiquitin-protein transferase activator activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0008284///positive regulation of cell proliferation+++GO:0016574///histone ubiquitination+++GO:0031507///heterochromatin assembly+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0045739///positive regulation of DNA repair+++GO:0050790///regulation of catalytic activity+++GO:0070301///cellular response to hydrogen peroxide 30953 30953 'Schip1' mRNA 1187.44 1242.45 1290.61 41.93 43.35 48.13 23.68 23.74 24.43 44.47 23.95 812.91 775.69 805 1240.166667 797.8666667 3.99E-12 -0.650785279 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0001553///luteinization+++GO:0001822///kidney development+++GO:0006807///nitrogen compound metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0010761///fibroblast migration+++GO:0035332///positive regulation of hippo signaling+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis 30954 30954 'Siva1' mRNA 962 965 906 85.2 84.24 84.9 83.65 82.48 82.97 84.78 83.03333333 1078 1031 1038 944.3333333 1049 0.139785971 0.140287419 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0001618///virus receptor activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005175///CD27 receptor binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0006924///activation-induced cell death of T cells+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0046718///viral entry into host cell+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 30955 30955 'Pik3cg' mRNA 70 46 63 0.63 0.38 0.61 4.27 4.09 3.92 0.54 4.093333333 573 522 505 59.66666667 533.3333333 1.82E-68 3.1458859 00562///Inositol phosphate metabolism+++04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04611///Platelet activation+++04725///Cholinergic synapse+++04921///Oxytocin signaling pathway+++05132///Salmonella infection+++05145///Toxoplasmosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005943///phosphatidylinositol 3-kinase complex, class IA+++GO:0005944///phosphatidylinositol 3-kinase complex, class IB+++GO:0016020///membrane" "GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0042802///identical protein binding+++GO:0046875///ephrin receptor binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity" GO:0001525///angiogenesis+++GO:0001932///regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0002675///positive regulation of acute inflammatory response+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0032252///secretory granule localization+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0043085///positive regulation of catalytic activity+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071320///cellular response to cAMP+++GO:0097284///hepatocyte apoptotic process+++GO:1903169///regulation of calcium ion transmembrane transport+++GO:2000270///negative regulation of fibroblast apoptotic process 30956 30956 'Aass' mRNA 819 836 881 12 12.05 13.69 9.35 8.08 9.32 12.58 8.916666667 735 620 709 845.3333333 688 0.005458094 -0.312208109 00310///Lysine degradation GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004753///saccharopine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0047130///saccharopine dehydrogenase (NADP+, L-lysine-forming) activity+++GO:0047131///saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity" GO:0006091///generation of precursor metabolites and energy+++GO:0008152///metabolic process+++GO:0019477///L-lysine catabolic process+++GO:0019878///lysine biosynthetic process via aminoadipic acid+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine 30957 30957 'Mapk8ip3' mRNA 2152 2033 2088 20.77 19.32 21.41 14.41 14.2 13.71 20.5 14.10666667 1717 1650 1580 2091 1649 3.64E-06 -0.355675402 04010///MAPK signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005790///smooth endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030673///axolemma+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:1904115///axon cytoplasm GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0016301///kinase activity+++GO:0019894///kinesin binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding GO:0001701///in utero embryonic development+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0007411///axon guidance+++GO:0007585///respiratory gaseous exchange+++GO:0008104///protein localization+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0016192///vesicle-mediated transport+++GO:0016310///phosphorylation+++GO:0030900///forebrain development+++GO:0031103///axon regeneration+++GO:0031175///neuron projection development+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0046328///regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0048286///lung alveolus development+++GO:0050821///protein stabilization+++GO:0060425///lung morphogenesis+++GO:0061564///axon development+++GO:0099641///anterograde axonal protein transport+++GO:2001224///positive regulation of neuron migration 30959 30959 'Ddx25' mRNA 124 138 95 4.31 4.72 3.5 1.36 1.46 2.03 4.176666667 1.616666667 45 47 65 119 52.33333333 3.71E-05 -1.189526259 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0033391///chromatoid body GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0006406///mRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0030154///cell differentiation+++GO:0051028///mRNA transport 30960 30960 'Vapa' mRNA 3421 3540 2639 120.31 122.76 98.35 96.48 136.99 129.61 113.8066667 121.0266667 3144 4341 4087 3200 3857.333333 0.198438009 0.267460989 04979///Cholesterol metabolism GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031965///nuclear membrane+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019904///protein domain specific binding+++GO:0033149///FFAT motif binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0008219///cell death+++GO:0031175///neuron projection development+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0044828///negative regulation by host of viral genome replication+++GO:0044829///positive regulation by host of viral genome replication+++GO:0070972///protein localization to endoplasmic reticulum+++GO:0090114///COPII-coated vesicle budding 30962 30962 'Slc7a9' mRNA 0 3 2 0 0.1 0.09 0.18 0 0.21 0.063333333 0.13 5 0 7 1.666666667 4 0.552795505 1.241416228 04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005515///protein binding+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015184///L-cystine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042605///peptide antigen binding GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015811///L-cystine transport+++GO:0055085///transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport 30963 30963 'Hacd1' mRNA 265 290 252 19.58 21.35 19.85 19.69 20.81 20.02 20.26 20.17333333 304 315 300 269 306.3333333 0.298453896 0.17769701 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0016829///lyase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0019899///enzyme binding+++GO:0046848///hydroxyapatite binding+++GO:0080023///3R-hydroxyacyl-CoA dehydratase activity+++GO:0102158///very-long-chain 3-hydroxyacyl-CoA dehydratase activity+++GO:0102343///3-hydroxy-arachidoyl-CoA dehydratase activity+++GO:0102344///3-hydroxy-behenoyl-CoA dehydratase activity+++GO:0102345///3-hydroxy-lignoceroyl-CoA dehydratase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007275///multicellular organism development+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0014902///myotube differentiation+++GO:0030148///sphingolipid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0034622///cellular protein-containing complex assembly+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0071529///cementum mineralization+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 317653 317653 'Klk14' mRNA 1 0 0 0.05 0 0 0.09 0.04 0.12 0.016666667 0.083333333 2.13 1 3.84 0.333333333 2.323333333 0.383181992 2.466605927 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0009566///fertilization+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0048730///epidermis morphogenesis+++GO:0070684///seminal clot liquefaction 317677 317677 'C1s2' mRNA 11.23 11.55 11.31 0.23 0.24 0.25 0.63 0.86 0.82 0.24 0.77 34.89 46.43 43.8 11.36333333 41.70666667 2.31E-04 1.8890162 04610///Complement and coagulation cascades+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response" 317717 317717 'Sec22a' mRNA 597 631 607 17.85 18.86 19.4 19.99 21.97 18.51 18.70333333 20.15666667 753 807 681 611.6666667 747 0.017812905 0.276813457 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 317750 317750 'Slc24a5' mRNA 311.84 260.09 491.73 9.13 7.5 15.26 10.01 12.45 11.76 10.63 11.40666667 393.19 477.4 447.1 354.5533333 439.23 0.235599511 0.285100069 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042470///melanosome "GO:0005262///calcium channel activity+++GO:0008273///calcium, potassium:sodium antiporter activity+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity" GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0030318///melanocyte differentiation+++GO:0034220///ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0050896///response to stimulus+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport 317755 317755 'Zar1' mRNA 6 1 0 0.29 0.05 0 0 0.04 0.13 0.113333333 0.056666667 0 1 3 2.333333333 1.333333333 0.778026136 -0.78302237 GO:0005737///cytoplasm GO:1903231///mRNA binding involved in posttranscriptional gene silencing GO:0006412///translation+++GO:0007275///multicellular organism development+++GO:0016441///posttranscriptional gene silencing 317757 317757 'Gimap5' mRNA 34 37.97 45.3 1 1.1 1.41 2.78 3.08 3.01 1.17 2.956666667 108.69 117.51 114.11 39.09 113.4366667 2.11E-07 1.532126218 GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032585///multivesicular body membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0001659///temperature homeostasis+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032831///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045838///positive regulation of membrane potential+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050868///negative regulation of T cell activation+++GO:0050995///negative regulation of lipid catabolic process" 317758 317758 'Gimap9' mRNA 72 66 62 3.12 2.82 2.85 4.75 4.95 5.69 2.93 5.13 126 128 146 66.66666667 133.3333333 8.22E-05 0.990094763 GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0046039///GTP metabolic process 319146 319146 'Ifnz' mRNA 0 3.4 5.14 0 0.14 0.22 0.06 0 0.08 0.12 0.046666667 1.79 0 2.32 2.846666667 1.37 0.557864184 -1.457915608 GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0097190///apoptotic signaling pathway 319148 319148 'H3c3' mRNA 1 0 1 0.18 0 0.19 0.54 0.34 0 0.123333333 0.293333333 3.41 2.04 0 0.666666667 1.816666667 0.683573272 1.285515454 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 319149 319149 'H3c4' mRNA 1 2 0 0.17 0.33 0 0.61 2.62 0.81 0.166666667 1.346666667 4.12 17.29 5.32 1 8.91 0.035082245 3.134363306 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 319151 319151 'H3c6' mRNA 7 5 8.62 0.5 0.36 0.66 1.19 0.88 1.04 0.506666667 1.036666667 18.97 13.6 16.04 6.873333333 16.20333333 0.133371219 1.212523453 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 319153 319153 'H3c11' mRNA 0 1 3 0 0.18 0.57 3.06 1.77 2.38 0.25 2.403333333 19.36 10.88 14.51 1.333333333 14.91666667 0.003415719 3.392253171 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 319154 319154 'H3c13' mRNA 7.43 6.14 0 1.25 1.03 0 1.28 1.47 0.97 0.76 1.24 8.66 9.61 6.31 4.523333333 8.193333333 0.53586835 0.840280771 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 319155 319155 'H4c3' mRNA 1.28 3.19 5.54 0.37 0.93 1.69 2.65 2.09 2.06 0.996666667 2.266666667 10.39 7.94 7.77 3.336666667 8.7 0.258571055 1.384631492 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319156 319156 'H4c4' mRNA 106 108 101 26.49 27.21 26.83 30.44 32.01 35.05 26.84333333 32.5 137.62 140 152 105 143.2066667 0.06487884 0.435017791 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319158 319158 'H4c9' mRNA 42.75 49.34 53.64 10.63 12.37 14.18 29.49 33.32 32.19 12.39333333 31.66666667 133.97 146.44 140.27 48.57666667 140.2266667 7.14E-09 1.527562639 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319159 319159 'H4c11' mRNA 1.27 1.17 2.63 0.29 0.27 0.63 0.52 1.82 0.48 0.396666667 0.94 2.57 8.78 2.31 1.69 4.553333333 0.389439871 1.572152662 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319160 319160 'H4c12' mRNA 2.53 4.13 1.76 0.61 1.01 0.45 2.09 2.05 1.06 0.69 1.733333333 9.76 9.26 4.77 2.806666667 7.93 0.206014209 1.654240667 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319161 319161 'H4c18' mRNA 15.99 14.82 13.16 3.92 3.66 3.43 9 8.84 8.42 3.67 8.753333333 41.49 39.42 37.22 14.65666667 39.37666667 0.003001285 1.46721651 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 319162 319162 'H2aw' mRNA 559.55 577.01 496.75 92.41 95.27 87.1 78.3 81.53 73.9 91.59333333 77.91 539.26 544.79 489.68 544.4366667 524.5766667 0.676316459 -0.063518022 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006337///nucleosome disassembly+++GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly+++GO:0070914///UV-damage excision repair 319164 319164 'H2ac6' mRNA 3.08 3.11 1.81 0.55 0.55 0.34 0.38 1.46 0.87 0.48 0.903333333 2.45 9.11 5.38 2.666666667 5.646666667 0.433785439 1.206169851 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319165 319165 'H2ac7' mRNA 9.14 3.33 7.93 1.39 0.51 1.28 1.94 5.15 3.02 1.06 3.37 14.55 37.46 21.82 6.8 24.61 0.010631707 1.9134557 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319166 319166 'H2ac8' mRNA 7.72 5.77 19.73 1.1 0.82 2.98 12.29 14.52 17.29 1.633333333 14.7 98.44 112.96 133.35 11.07333333 114.9166667 7.61E-16 3.443269439 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319167 319167 'H2ac11' mRNA 3.83 0 0 0.72 0 0 0.58 0 0.45 0.24 0.343333333 3.53 0 2.6 1.276666667 2.043333333 0.831836875 0.732450829 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319171 319171 'H2ac24' mRNA 29.76 42.74 35.71 5.99 8.64 7.64 80.36 108.15 92.26 7.423333333 93.59 452.68 590.24 499.31 36.07 514.0766667 1.47E-73 3.853480541 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319172 319172 'H2ac4' mRNA 0 2.21 3.6 0 0.37 0.64 7.62 7.71 6.47 0.336666667 7.266666667 51.97 51 42.44 1.936666667 48.47 2.41E-09 4.831831421 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319176 319176 'H2ac20' mRNA 23.04 14.65 30.95 4.37 2.78 6.23 5.8 8.02 9.49 4.46 7.77 34.77 46.57 54.66 22.88 45.33333333 0.047048615 0.979996408 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 319178 319178 'H2bc3' mRNA 5.14 2.11 2.26 0.9 0.37 0.42 0.37 0.54 0.36 0.563333333 0.423333333 2.39 3.38 2.22 3.17 2.663333333 0.863090843 -0.364727734 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly 319179 319179 'H2bc6' mRNA 71.1 63.69 75.41 2.26 2.16 3.14 3.04 1.03 1.88 2.52 1.983333333 61.58 51.5 79.14 70.06666667 64.07333333 0.735918097 -0.145452587 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319180 319180 'H2bc7' mRNA 0 1.17 0 0 0.24 0 0.23 0 0 0.08 0.076666667 1.27 0 0 0.39 0.423333333 0.998591786 -0.011756601 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319181 319181 'H2bc8' mRNA 11.76 1.85 4.03 2.26 0.36 0.82 1.7 4.9 4 1.146666667 3.533333333 10.05 28.01 22.7 5.88 20.25333333 0.03051641 1.905443314 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319182 319182 'H2bc9' mRNA 1.01 4.1 1.49 0.16 0.65 0.25 0 0.3 0.71 0.353333333 0.336666667 0 2.07 4.91 2.2 2.326666667 0.998591786 0.018053234 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0097677///STAT family protein binding GO:0006334///nucleosome assembly 319183 319183 'H2bc11' mRNA 1.11 1.11 4.53 0.22 0.22 0.94 1.68 1.42 1.63 0.46 1.576666667 9.79 8.05 9.16 2.25 9 0.092920322 2.081828631 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319184 319184 'H2bc12' mRNA 2.83 2.91 11.57 0.48 0.49 2.08 1.35 1.47 0.72 1.016666667 1.18 9.09 9.57 4.65 5.77 7.77 0.729224978 0.503035532 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0031640///killing of cells of other organism+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319185 319185 'H2bc13' mRNA 4.16 4.47 0 0.77 0.83 0 0.77 0.96 1.65 0.533333333 1.126666667 4.73 5.7 9.71 2.876666667 6.713333333 0.431103393 1.188165875 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319186 319186 'H2bc14' mRNA 0 0 3.01 0 0 0.57 0.67 0.49 0.59 0.19 0.583333333 4.25 3 3.59 1.003333333 3.613333333 0.444143502 1.673492023 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly 319187 319187 'H2bc15' mRNA 0 1.18 1.11 0 0.22 0.22 0 0.71 0.46 0.146666667 0.39 0 4.26 2.73 0.763333333 2.33 0.583675133 1.580847599 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319188 319188 'H2bc22' mRNA 0 2.23 0 0 0.39 0 0.64 0 0 0.13 0.213333333 3.66 0 0 0.743333333 1.22 0.886295299 0.583995984 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly 319189 319189 'H2bc18' mRNA 25 24 33 4.34 4.17 6.08 8.4 5.82 9.84 4.863333333 8.02 55 37 62 27.33333333 51.33333333 0.042643875 0.888970148 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0001530///lipopolysaccharide binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly 319190 319190 'H2bc21' mRNA 567 630 487 11.78 12.89 10.73 7.28 7.18 6.7 11.8 7.053333333 403 388 359 561.3333333 383.3333333 9.40E-06 -0.558343532 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0001530///lipopolysaccharide binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0019731///antibacterial humoral response+++GO:0031640///killing of cells of other organism+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 319191 319191 'H2ac13' mRNA 2.79 6.93 2.48 0.57 1.42 0.54 3.77 1.66 2.14 0.843333333 2.523333333 20.88 8.9 11.39 4.066666667 13.72333333 0.052294948 1.955011647 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 319192 319192 'H2ac19' mRNA 39.44 28.59 0 5.08 3.66 0 0.87 2.33 3.26 2.913333333 2.153333333 7.69 20.08 27.86 22.67666667 18.54333333 0.892638561 -0.276270573 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 319195 319195 'Rpl17' mRNA 1170.31 1211.92 1137.78 104.58 107.85 107.3 173.37 171.52 173.68 106.5766667 172.8566667 2211.06 2133.24 2139.55 1173.336667 2161.283333 8.71E-35 0.870400941 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0031672///A band+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0070180///large ribosomal subunit rRNA binding GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 319196 319196 'Ankef1' mRNA 122 97 98 2.48 1.94 2.11 0.09 0.27 0.42 2.176666667 0.26 5 15 23 105.6666667 14.33333333 1.59E-12 -2.887959002 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319197 319197 'Gpr4' mRNA 497 436 454 9.49 8.2 9.2 3.37 2.92 3.38 8.963333333 3.223333333 203 172 197 462.3333333 190.6666667 6.80E-19 -1.291144229 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0010447///response to acidic pH+++GO:0016525///negative regulation of angiogenesis+++GO:0030155///regulation of cell adhesion+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0043114///regulation of vascular permeability+++GO:0050729///positive regulation of inflammatory response+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060055///angiogenesis involved in wound healing+++GO:0072144///glomerular mesangial cell development 319200 319200 'Gpr82' mRNA 66.64 89.34 79.06 0.31 0.26 0.24 0.69 0.75 0.83 0.27 0.756666667 96.18 104.24 121.92 78.34666667 107.4466667 0.126354191 0.445309904 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 319207 319207 'Pgbd1' mRNA 165 175 149 3.27 3.21 2.89 1.14 1.52 1.09 3.123333333 1.25 71 90 65 163 75.33333333 2.26E-06 -1.121487383 GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding 319211 319211 'Nol4' mRNA 86 95 77 0.92 0.98 0.87 0.11 0.03 0.02 0.923333333 0.053333333 11 2 2 86 5 6.39E-15 -4.119139491 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0008150///biological_process 319236 319236 'Trim12c' mRNA 395.51 408.15 338.03 6.44 6.38 5.39 6.94 5.49 6.53 6.07 6.32 485.6 366.16 436.44 380.5633333 429.4 0.311655982 0.162877535 05170///Human immunodeficiency virus 1 infection GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990462///omegasome "GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000209///protein polyubiquitination+++GO:0002218///activation of innate immune response+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0070534///protein K63-linked ubiquitination+++GO:1902187///negative regulation of viral release from host cell" 319239 319239 'Npsr1' mRNA 1 0 4 0.01 0 0.06 0 0.03 0 0.023333333 0.01 0 2 0 1.666666667 0.666666667 0.68492124 -1.365494394 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005000///vasopressin receptor activity+++GO:0008188///neuropeptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0042755///eating behavior+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060013///righting reflex+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1903999///negative regulation of eating behavior+++GO:2000293///negative regulation of defecation 319259 319259 'Bricd5' mRNA 6668.86 6850.32 6710.39 427.97 434.77 456.94 221.37 232.41 217.05 439.8933333 223.61 3954.8 4046.78 3747.22 6743.19 3916.266667 3.96E-39 -0.796308608 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0042127///regulation of cell proliferation 319262 319262 'Fchsd1' mRNA 384.38 330.76 368.84 4.92 4.13 4.99 3.22 3.2 2.79 4.68 3.07 292.33 284.75 243.41 361.3266667 273.4966667 0.009277724 -0.415789097 GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0032437///cuticular plate+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0055037///recycling endosome GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0007274///neuromuscular synaptic transmission+++GO:0030833///regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0044803///multi-organism membrane organization 319263 319263 'Pcmtd1' mRNA 2665.12 2712.96 2709.45 26.84 26.85 28.89 21.61 19.37 19.99 27.52666667 20.32333333 2456.55 2152 2199.14 2695.843333 2269.23 4.21E-04 -0.262330863 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0004719///protein-L-isoaspartate (D-aspartate) O-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0006464///cellular protein modification process+++GO:0006479///protein methylation+++GO:0032259///methylation 319266 319266 'A130010J15Rik' mRNA 409.48 428.37 348.2 5.75 5.92 5.22 4.08 3.62 4.34 5.63 4.013333333 332.36 285.19 340.98 395.35 319.51 0.03215339 -0.317555604 GO:0005575///cellular_component+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319277 319277 'Washc4' mRNA 1052.08 1090.93 1129.96 9.72 9.96 11.1 18.61 18.45 18.52 10.26 18.52666667 2281.28 2228.57 2200.65 1090.99 2236.833333 1.90E-38 1.02277135 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0031083///BLOC-1 complex+++GO:0071203///WASH complex GO:0003674///molecular_function GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0016197///endosomal transport 319278 319278 'Shfl' mRNA 893.69 931.11 845.3 21.31 21.97 22.22 24.02 25.69 25.11 21.83333333 24.94 1051.7 1089.03 1063.83 890.0333333 1068.186667 0.005988675 0.252873727 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0043022///ribosome binding+++GO:1990825///sequence-specific mRNA binding GO:0006449///regulation of translational termination+++GO:0034340///response to type I interferon+++GO:0034341///response to interferon-gamma+++GO:0034342///response to type III interferon+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0075523///viral translational frameshifting+++GO:2001125///negative regulation of translational frameshifting 319322 319322 'Sf3b2' mRNA 7858 8005 7656 132.84 133.15 137.29 93.77 94.58 94.5 134.4266667 94.28333333 6383 6288 6229 7839.666667 6300 4.96E-10 -0.327228822 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0005515///protein binding "GO:0000398///mRNA splicing, via spliceosome" 319352 319352 'Pianp' mRNA 688.57 723.35 499.31 18.25 19.19 14.14 22.31 19.55 20.87 17.19333333 20.91 942 805 855 637.0766667 867.3333333 3.19E-04 0.439806702 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0050776///regulation of immune response 319370 319370 'Ubald2' mRNA 350 363 195 13.98 14.3 8.26 7.93 6.88 7.26 12.18 7.356666667 228 193 202 302.6666667 207.6666667 0.010442759 -0.544532992 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319387 319387 'Adgrl3' mRNA 965 923 891 5.36 4.9 5.19 2.05 1.84 1.58 5.15 1.823333333 403 367 315 926.3333333 361.6666667 3.17E-34 -1.369239507 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0098978///glutamatergic synapse GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0001764///neuron migration+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007416///synapse assembly+++GO:0007420///brain development+++GO:0031987///locomotion involved in locomotory behavior+++GO:0042220///response to cocaine+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 319415 319415 'Hs3st5' mRNA 446 428 356 8.02 7.59 6.77 0.58 0.3 0.82 7.46 0.566666667 37 18 51 410 35.33333333 6.41E-51 -3.546221818 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity "GO:0006477///protein sulfation+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification+++GO:0046596///regulation of viral entry into host cell+++GO:0050819///negative regulation of coagulation" 319430 319430 'C5ar2' mRNA 9 24 31.53 0.14 0.46 0.54 1.54 1.1 1.5 0.38 1.38 111.57 75.78 103 21.51 96.78333333 1.04E-07 2.149922125 GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell GO:0004875///complement receptor activity+++GO:0004878///complement component C5a receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0002430///complement receptor mediated signaling pathway+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0032677///regulation of interleukin-8 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0038178///complement component C5a signaling pathway+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0090024///negative regulation of neutrophil chemotaxis 319433 319433 'Serpine3' mRNA 334 387 332 12.98 14.79 13.51 1.16 1.32 1.43 13.76 1.303333333 34 37 40 351 37 6.32E-53 -3.255700327 GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity 319446 319446 'Dpep2' mRNA 14 10 16 0.43 0.38 0.57 21.86 22.2 21.65 0.46 21.90333333 724 724 699 13.33333333 715.6666667 2.58E-107 5.734330862 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008238///exopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0006691///leukotriene metabolic process 319448 319448 'Fndc3a' mRNA 2358 2225 2114.04 19.16 17.87 17.82 18.4 16.4 16.38 18.28333333 17.06 2612 2262 2256 2232.346667 2376.666667 0.375082593 0.078150118 GO:0000139///Golgi membrane+++GO:0001669///acrosomal vesicle+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0060009///Sertoli cell development+++GO:0098609///cell-cell adhesion 319455 319455 'Pld5' mRNA 275.79 298.19 290.49 1.55 1.7 1.86 0.81 0.92 0.81 1.703333333 0.846666667 166.37 184.97 165.57 288.1566667 172.3033333 7.92E-06 -0.756520843 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0003824///catalytic activity GO:0008150///biological_process 319468 319468 'Ppm1h' mRNA 2780.57 2625.19 2620.47 17.6 14.67 17.4 12.62 10.95 12.04 16.55666667 11.87 2527.66 2157.79 2289.8 2675.41 2325.083333 0.004479947 -0.216130872 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042802///identical protein binding GO:0006470///protein dephosphorylation 319475 319475 'Zfp672' mRNA 1522.23 1505.75 1644.35 17.39 16.4 19.72 10.18 11.24 10.79 17.83666667 10.73666667 1032.08 1036.45 1014.99 1557.443333 1027.84 1.50E-11 -0.614409139 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 319476 319476 'Lrtm1' mRNA 41 12 6 0.3 0.09 0.05 0.03 0.01 0.05 0.146666667 0.03 5 2 7 19.66666667 4.666666667 0.026349084 -2.070343638 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008201///heparin binding+++GO:0048495///Roundabout binding GO:0007411///axon guidance+++GO:0050919///negative chemotaxis+++GO:0051965///positive regulation of synapse assembly 319477 319477 'Insyn1' mRNA 79 68 37 2.05 1.74 1.02 0.11 0.21 0.14 1.603333333 0.153333333 5 9 6 61.33333333 6.666666667 1.93E-09 -3.198300761 GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005515///protein binding GO:0060080///inhibitory postsynaptic potential 319478 319478 'Cxxc4' mRNA 695.07 723 611 4.57 4.53 4.44 0.77 0.9 0.81 4.513333333 0.826666667 155 170 152 676.3566667 159 9.77E-57 -2.097292097 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway 319480 319480 'Itga11' mRNA 60 51 75 0.65 0.54 0.86 0.87 0.59 0.83 0.683333333 0.763333333 92 63 88 62 81 0.316762946 0.363932011 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034681///integrin alpha11-beta1 complex GO:0005518///collagen binding+++GO:0038064///collagen receptor activity+++GO:0046872///metal ion binding+++GO:0098639///collagen binding involved in cell-matrix adhesion GO:0006929///substrate-dependent cell migration+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:0033627///cell adhesion mediated by integrin+++GO:0038065///collagen-activated signaling pathway 319481 319481 'Wdr59' mRNA 249 212 192 2.59 2.17 2.12 1.83 1.79 1.91 2.293333333 1.843333333 202 193 201 217.6666667 198.6666667 0.516886203 -0.141109785 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0061700///GATOR2 complex GO:0003674///molecular_function GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation 319482 319482 '9530053A07Rik' mRNA 19.23 8 11.23 0.13 0.05 0.08 0.18 0.18 0.09 0.086666667 0.15 30.99 30.38 15 12.82 25.45666667 0.148884821 0.969130778 GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0008150///biological_process 319486 319486 'A430057M04Rik' mRNA 17.06 24.31 15.05 0.19 0.27 0.18 0.38 0.35 0.59 0.213333333 0.44 38.19 34.29 57.46 18.80666667 43.31333333 0.013923361 1.198304453 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319504 319504 'Nrcam' mRNA 2496 2616 2413 13.51 14.13 13.95 5.42 5.04 4.81 13.86333333 5.09 1099 999 932 2508.333333 1010 4.18E-68 -1.324381466 04514///Cell adhesion molecules GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0033268///node of Ranvier+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0030506///ankyrin binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0008104///protein localization+++GO:0010975///regulation of neuron projection development+++GO:0019227///neuronal action potential propagation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0034113///heterotypic cell-cell adhesion+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0070593///dendrite self-avoidance+++GO:0098609///cell-cell adhesion+++GO:0099175///regulation of postsynapse organization 319508 319508 'Syt15' mRNA 74 79.88 61.15 1.11 1.18 1 0.89 1.09 1.1 1.096666667 1.026666667 66.34 81.85 72.61 71.67666667 73.6 0.945363669 0.027239035 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0070382///exocytic vesicle GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0030276///clathrin binding GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0071277///cellular response to calcium ion 319513 319513 'Pced1a' mRNA 523.54 497.34 490.8 8.36 7.74 8.51 7.45 7.44 7.25 8.203333333 7.38 530.11 506.96 479.88 503.8933333 505.65 0.966087461 -0.007326564 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319518 319518 'Pdpr' mRNA 678 775 621 4.85 5.42 4.61 3.82 3.78 3.78 4.96 3.793333333 632 604 585 691.3333333 607 0.094820973 -0.196725215 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0016491///oxidoreductase activity 319520 319520 'Dusp4' mRNA 99 109 100 2.28 2.47 2.44 3.36 3.65 3.16 2.396666667 3.39 168 178 153 102.6666667 166.3333333 0.001812296 0.685270513 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding+++GO:1990439///MAP kinase serine/threonine phosphatase activity GO:0000188///inactivation of MAPK activity+++GO:0001706///endoderm formation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 319530 319530 'Zfp750' mRNA 479 497 501 8.07 8.24 8.95 5.11 4.75 4.94 8.42 4.933333333 349 317 327 492.3333333 331 5.39E-06 -0.586380855 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008544///epidermis development+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 319535 319535 'Zfp182' mRNA 508 539 455 3.72 3.86 3.51 2.73 2.47 2.61 3.696666667 2.603333333 433 384 399 500.6666667 405.3333333 0.013217059 -0.314903429 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 319552 319552 'Spx' mRNA 1 2 0 0.04 0.08 0 0.23 0.38 0.38 0.04 0.33 7 11 11 1 9.666666667 0.0168879 3.281647078 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0030133///transport vesicle+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0031765///type 2 galanin receptor binding+++GO:0031766///type 3 galanin receptor binding GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0010459///negative regulation of heart rate+++GO:0032099///negative regulation of appetite+++GO:0035814///negative regulation of renal sodium excretion+++GO:0044539///long-chain fatty acid import+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051930///regulation of sensory perception of pain+++GO:1904306///positive regulation of gastro-intestinal system smooth muscle contraction 319554 319554 'Idi1' mRNA 2466 2331 2656 47.4 44.1 54.16 28.34 26.72 26.25 48.55333333 27.10333333 1696 1562 1521 2484.333333 1593 5.80E-14 -0.657363148 00900///Terpenoid backbone biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0000287///magnesium ion binding+++GO:0004452///isopentenyl-diphosphate delta-isomerase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0009240///isopentenyl diphosphate biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0035634///response to stilbenoid+++GO:0050992///dimethylallyl diphosphate biosynthetic process 319555 319555 'Nwd1' mRNA 165 192 118 1.05 1.32 0.81 0.24 0.17 0.09 1.06 0.166666667 35 38 16 158.3333333 29.66666667 2.62E-14 -2.419288787 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding GO:0010628///positive regulation of gene expression+++GO:0032088///negative regulation of NF-kappaB transcription factor activity 319565 319565 'Syne2' mRNA 3777.97 3892.98 3791.94 9.01 9.12 9.59 4.49 4.06 4.09 9.24 4.213333333 2166.99 1914.96 1912.99 3820.963333 1998.313333 5.12E-45 -0.948903729 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030016///myofibril+++GO:0030018///Z disc+++GO:0031258///lamellipodium membrane+++GO:0031527///filopodium membrane+++GO:0031965///nuclear membrane+++GO:0031981///nuclear lumen+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0045111///intermediate filament cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0006998///nuclear envelope organization+++GO:0007097///nuclear migration+++GO:0007163///establishment or maintenance of cell polarity+++GO:0010761///fibroblast migration+++GO:0021817///nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration+++GO:0030335///positive regulation of cell migration+++GO:0031022///nuclear migration along microfilament+++GO:0034504///protein localization to nucleus+++GO:0051642///centrosome localization+++GO:1902017///regulation of cilium assembly 319579 319579 'Defb20' mRNA 1 2 6 0.1 0.21 0.66 0.09 0 0 0.323333333 0.03 1 0 0 3 0.333333333 0.197871558 -3.111804927 GO:0005576///extracellular region GO:0003674///molecular_function GO:0006952///defense response+++GO:0031640///killing of cells of other organism+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium 319581 319581 'Xkr5' mRNA 5 5 8 0.12 0.1 0.19 0.53 0.37 0.37 0.136666667 0.423333333 32 21 22 6 25 0.003117509 2.035941011 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0043652///engulfment of apoptotic cell+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:1902742///apoptotic process involved in development 319582 319582 'Trmt9b' mRNA 236 232 214 3.09 3.07 3.05 1.36 1.45 1.8 3.07 1.536666667 122 120.78 147 227.3333333 129.9266667 1.81E-05 -0.820244568 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000049///tRNA binding+++GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016300///tRNA (uracil) methyltransferase activity+++GO:0016740///transferase activity GO:0002098///tRNA wobble uridine modification+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 319583 319583 'Lig4' mRNA 160 203 174 2.12 2.65 2.45 1.6 2.17 1.93 2.406666667 1.9 139 184 162 179 161.6666667 0.545267738 -0.155422289 03450///Non-homologous end-joining GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005958///DNA-dependent protein kinase-DNA ligase 4 complex+++GO:0032807///DNA ligase IV complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070419///nonhomologous end joining complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003909///DNA ligase activity+++GO:0003910///DNA ligase (ATP) activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding "GO:0000012///single strand break repair+++GO:0001701///in utero embryonic development+++GO:0002328///pro-B cell differentiation+++GO:0006260///DNA replication+++GO:0006266///DNA ligation+++GO:0006281///DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007417///central nervous system development+++GO:0008283///cell proliferation+++GO:0010165///response to X-ray+++GO:0010212///response to ionizing radiation+++GO:0010332///response to gamma radiation+++GO:0033077///T cell differentiation in thymus+++GO:0033151///V(D)J recombination+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0033153///T cell receptor V(D)J recombination+++GO:0035019///somatic stem cell population maintenance+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045190///isotype switching+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0051102///DNA ligation involved in DNA recombination+++GO:0051103///DNA ligation involved in DNA repair+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051402///neuron apoptotic process+++GO:0071285///cellular response to lithium ion+++GO:0071479///cellular response to ionizing radiation+++GO:0071897///DNA biosynthetic process+++GO:0097680///double-strand break repair via classical nonhomologous end joining+++GO:2001252///positive regulation of chromosome organization" 319586 319586 'Celf5' mRNA 46 30 27 0.68 0.45 0.44 0.35 0.24 0.3 0.523333333 0.296666667 20 20 26 34.33333333 22 0.223448684 -0.648397298 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing" 319594 319594 'Hif1an' mRNA 1121 1166 1041 9.6 9.82 9.46 7.91 6.97 6.99 9.626666667 7.29 1064 916 911 1109.333333 963.6666667 0.025134154 -0.214689171 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm "GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0031406///carboxylic acid binding+++GO:0036139///peptidyl-histidine dioxygenase activity+++GO:0036140///peptidyl-asparagine 3-dioxygenase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0051213///dioxygenase activity+++GO:0071532///ankyrin repeat binding+++GO:0102113///hypoxia-inducible factor-asparagine oxygenase activity" GO:0036138///peptidyl-histidine hydroxylation+++GO:0042264///peptidyl-aspartic acid hydroxylation+++GO:0042265///peptidyl-asparagine hydroxylation+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia 319601 319601 'Zfp653' mRNA 161 154 114 4.16 3.92 3.1 2.14 1.62 2.45 3.726666667 2.07 95 71 106 143 90.66666667 0.009795353 -0.66464515 GO:0005576///extracellular region+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding+++GO:0050682///AF-2 domain binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1900116///extracellular negative regulation of signal transduction+++GO:1903507///negative regulation of nucleic acid-templated transcription" 319604 319604 'Fam168a' mRNA 1456 1445 1227 11.63 11.36 10.36 8.76 8.32 8.62 11.11666667 8.566666667 1260 1173 1202 1376 1211.666667 0.025770674 -0.192824186 GO:0005575///cellular_component GO:0003674///molecular_function GO:1905053///positive regulation of base-excision repair 319613 319613 'Sybu' mRNA 488 547 529 9.58 10.68 11.49 1.56 1.62 1.29 10.58333333 1.49 87 95 75 521.3333333 85.66666667 4.64E-57 -2.617914922 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097433///dense body+++GO:1904115///axon cytoplasm GO:0008017///microtubule binding+++GO:0017075///syntaxin-1 binding+++GO:0019894///kinesin binding GO:0019896///axonal transport of mitochondrion+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0060025///regulation of synaptic activity+++GO:0060074///synapse maturation+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:1990048///anterograde neuronal dense core vesicle transport 319615 319615 'Zfp944' mRNA 393.61 434.31 389.1 6.28 6.78 6.32 6.46 5.97 6.04 6.46 6.156666667 473.13 413.17 444.65 405.6733333 443.65 0.437706789 0.117513021 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 319618 319618 'Dcp1b' mRNA 315 264 330 5.16 4.23 5.74 3.24 3.45 3.05 5.043333333 3.246666667 229 236 209 303 224.6666667 0.012166555 -0.447347991 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0016787///hydrolase activity+++GO:0030234///enzyme regulator activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0031087///deadenylation-independent decapping of nuclear-transcribed mRNA+++GO:0034504///protein localization to nucleus+++GO:0043085///positive regulation of catalytic activity+++GO:0097398///cellular response to interleukin-17+++GO:0110012///protein localization to P-body" 319622 319622 'Itpripl2' mRNA 152 119 125 1.17 0.9 1.02 2.56 2.21 2.84 1.03 2.536666667 383 323 411 132 372.3333333 1.07E-17 1.483845168 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319625 319625 'Galm' mRNA 1115 1308 1191 28.04 32.62 31.89 23.91 21.9 21.84 30.85 22.55 1090 977 966 1204.666667 1011 0.006656717 -0.265475919 00010///Glycolysis / Gluconeogenesis+++00052///Galactose metabolism GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004034///aldose 1-epimerase activity+++GO:0016853///isomerase activity+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006012///galactose metabolic process+++GO:0019318///hexose metabolic process+++GO:0033499///galactose catabolic process via UDP-galactose 319634 319634 'Efcab5' mRNA 25.22 11.09 9.87 0.18 0.07 0.07 0.07 0.08 0.05 0.106666667 0.066666667 13 14.29 9.16 15.39333333 12.15 0.734312035 -0.32414223 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 319636 319636 'Fsd1l' mRNA 517.92 499 547 5.63 4.89 6.77 2.86 2.47 2.26 5.763333333 2.53 276 214 210 521.3066667 233.3333333 1.09E-15 -1.175490117 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319638 319638 'Nt5dc1' mRNA 473 419 491 9.7 9.28 10.6 9 7.85 9.57 9.86 8.806666667 459 397 488 461 448 0.762567515 -0.057063042 GO:0005575///cellular_component GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 319642 319642 'Rab9b' mRNA 29 53 57 0.42 0.75 0.87 0.42 0.38 0.22 0.68 0.34 34 30 17 46.33333333 27 0.106211944 -0.799911067 05132///Salmonella infection+++05162///Measles GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding "GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0042147///retrograde transport, endosome to Golgi" 319651 319651 'Usp37' mRNA 995 1004 1026 7.32 7.27 8.03 5.2 5.61 5.39 7.54 5.4 810 858 820 1008.333333 829.3333333 0.003129594 -0.294463505 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006275///regulation of DNA replication+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0016579///protein deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0051301///cell division+++GO:0071108///protein K48-linked deubiquitination 319653 319653 'Slc25a40' mRNA 1677.81 1680.28 1567.14 5.67 5.38 5.96 4.98 5.14 5.14 5.67 5.086666667 1645.39 1426.03 1538.14 1641.743333 1536.52 0.21655323 -0.107414501 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0055085///transmembrane transport 319655 319655 'Podxl2' mRNA 1577 1528 1188 43.39 41.47 34.68 17.98 19.47 18.7 39.84666667 18.71666667 752 794 751 1431 765.6666667 3.08E-20 -0.908262387 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0050901///leukocyte tethering or rolling 319660 319660 'Agmo' mRNA 146 185 186 3.83 4.97 5.57 1.6 1.27 1.57 4.79 1.48 70 52 57 172.3333333 59.66666667 3.88E-10 -1.546788336 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0050479///glyceryl-ether monooxygenase activity GO:0006643///membrane lipid metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0046485///ether lipid metabolic process 319670 319670 'Eml5' mRNA 522.13 518.41 363.59 3.05 2.84 2.42 1.44 1.51 1.51 2.77 1.486666667 234.18 282.78 274.69 468.0433333 263.8833333 1.55E-07 -0.831575171 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0008017///microtubule binding GO:0008150///biological_process 319675 319675 'Cep295' mRNA 342.97 330.5 324.83 2.15 2.05 2.16 1.72 1.64 1.89 2.12 1.75 314.7 291.07 331.3 332.7666667 312.3566667 0.571225969 -0.101630653 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:1990498///mitotic spindle microtubule GO:0008017///microtubule binding GO:0007099///centriole replication+++GO:0010825///positive regulation of centrosome duplication+++GO:0046599///regulation of centriole replication+++GO:1901985///positive regulation of protein acetylation+++GO:1903724///positive regulation of centriole elongation+++GO:1904951///positive regulation of establishment of protein localization 319695 319695 'Ankar' mRNA 0 1 1 0 0.02 0.02 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0016020///membrane+++GO:0016021///integral component of membrane 319701 319701 'Fbxo48' mRNA 6.99 10.66 8 0.07 0.1 0.07 0.4 0.34 0.22 0.08 0.32 30.06 24.13 15.02 8.55 23.07 0.028779756 1.509563709 GO:0019005///SCF ubiquitin ligase complex GO:0003674///molecular_function GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 319710 319710 'Frmd6' mRNA 901 938 899 10.28 10.52 10.89 20.85 19.41 19.61 10.56333333 19.95666667 2107 1913 1914 912.6666667 1978 5.66E-46 1.103301967 04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043296///apical junction complex GO:0005515///protein binding GO:0003383///apical constriction+++GO:0031032///actomyosin structure organization+++GO:0032970///regulation of actin filament-based process+++GO:0034613///cellular protein localization 319713 319713 'Ablim3' mRNA 1507 1514 1376 20.3 19.92 19.51 6.05 6.09 6.13 19.91 6.09 517 513 515 1465.666667 515 1.26E-69 -1.519308177 04360///Axon guidance GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding "GO:0006351///transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0030032///lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060271///cilium assembly" 319719 319719 'Simc1' mRNA 160 209 211 2.05 2.36 2.92 2.07 1.59 1.55 2.443333333 1.736666667 200 158 155 193.3333333 171 0.430910839 -0.19397065 GO:0005737///cytoplasm+++GO:0030017///sarcomere GO:0030414///peptidase inhibitor activity+++GO:0032184///SUMO polymer binding GO:0008150///biological_process+++GO:0010466///negative regulation of peptidase activity 319734 319734 'Cacna2d4' mRNA 2867 2899 2432 42.38 42.13 38.12 4.42 4.2 3.96 40.87666667 4.193333333 348 316 305 2732.666667 323 8.53E-276 -3.089914082 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0070588///calcium ion transmembrane transport 319740 319740 'Zfyve27' mRNA 1664.73 1830.09 1656.92 16.05 17.36 16.91 13.56 12.85 12.07 16.77333333 12.82666667 1616.87 1496.06 1393 1717.246667 1501.976667 0.016000025 -0.204856212 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032584///growth cone membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding GO:0016192///vesicle-mediated transport+++GO:0031175///neuron projection development+++GO:0045773///positive regulation of axon extension+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0072659///protein localization to plasma membrane 319742 319742 'Mpzl3' mRNA 313 343 318 4.97 5.36 5.35 6.29 5.79 5.53 5.226666667 5.87 456 410 388 324.6666667 418 0.01273435 0.352121006 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0042633///hair cycle 319748 319748 'Zfp865' mRNA 197 202 97 2.78 2.64 1.33 1.27 1.08 0.89 2.25 1.08 107 94 77 165.3333333 92.66666667 0.003191936 -0.834498482 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 319757 319757 'Smo' mRNA 1222 1294 660 19.89 20.54 11.73 12.7 13.28 14.85 17.38666667 13.61 873 921 997 1058.666667 930.3333333 0.612251631 -0.182824936 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04360///Axon guidance+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0030666///endocytic vesicle membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0060170///ciliary membrane+++GO:0097731///9+0 non-motile cilium GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005113///patched binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001570///vasculogenesis+++GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0001708///cell fate specification+++GO:0001755///neural crest cell migration+++GO:0001947///heart looping+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003007///heart morphogenesis+++GO:0003140///determination of left/right asymmetry in lateral mesoderm+++GO:0003323///type B pancreatic cell development+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007228///positive regulation of hh target transcription factor activity+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007371///ventral midline determination+++GO:0007389///pattern specification process+++GO:0007417///central nervous system development+++GO:0007494///midgut development+++GO:0008284///positive regulation of cell proliferation+++GO:0009952///anterior/posterior pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0021542///dentate gyrus development+++GO:0021696///cerebellar cortex morphogenesis+++GO:0021794///thalamus development+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021910///smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0021953///central nervous system neuron differentiation+++GO:0021987///cerebral cortex development+++GO:0030335///positive regulation of cell migration+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0031069///hair follicle morphogenesis+++GO:0034504///protein localization to nucleus+++GO:0035264///multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046622///positive regulation of organ growth+++GO:0048143///astrocyte activation+++GO:0048468///cell development+++GO:0048565///digestive tract development+++GO:0048568///embryonic organ development+++GO:0048589///developmental growth+++GO:0048741///skeletal muscle fiber development+++GO:0048745///smooth muscle tissue development+++GO:0048846///axon extension involved in axon guidance+++GO:0048853///forebrain morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050821///protein stabilization+++GO:0051451///myoblast migration+++GO:0051799///negative regulation of hair follicle development+++GO:0060242///contact inhibition+++GO:0060413///atrial septum morphogenesis+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060684///epithelial-mesenchymal cell signaling+++GO:0061053///somite development+++GO:0061113///pancreas morphogenesis+++GO:0070986///left/right axis specification+++GO:0071397///cellular response to cholesterol+++GO:0071679///commissural neuron axon guidance+++GO:0072285///mesenchymal to epithelial transition involved in metanephric renal vesicle formation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1901215///negative regulation of neuron death+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:2000036///regulation of stem cell population maintenance+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000826///regulation of heart morphogenesis" 319758 319758 'Rfx7' mRNA 439 457 423 2.89 2.96 2.96 2.46 1.96 2.14 2.936666667 2.186666667 429 335 363 439.6666667 375.6666667 0.09880183 -0.240004212 "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 319764 319764 'A730046J19Rik' mRNA 1 1 3 0.01 0.01 0.04 0 0 0.01 0.02 0.003333333 0 0 1 1.666666667 0.333333333 0.458801983 -2.257157989 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle 319765 319765 'Igf2bp2' mRNA 657 657 497 9.11 8.96 7.31 4.77 5.13 4.99 8.46 4.963333333 396 416 401 603.6666667 404.3333333 4.45E-06 -0.584190853 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0048027///mRNA 5'-UTR binding GO:0006417///regulation of translation+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0051028///mRNA transport+++GO:0051252///regulation of RNA metabolic process 319767 319767 'Atp10b' mRNA 190 161 163 1.43 1.18 1.28 0.44 0.39 0.43 1.296666667 0.42 69 58 64 171.3333333 63.66666667 6.03E-10 -1.440582195 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:1905103///integral component of lysosomal membrane+++GO:1990531///phospholipid-translocating ATPase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0015914///phospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation+++GO:0097212///lysosomal membrane organization 319772 319772 'C130050O18Rik' mRNA 65 79 52 1.84 2.33 1.58 5.23 6.6 5.21 1.916666667 5.68 199 237 195 65.33333333 210.3333333 1.82E-13 1.681910933 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319776 319776 'Tmem72' mRNA 257 275 255 3.75 3.93 3.9 4.08 3.84 3.58 3.86 3.833333333 326 292 274 262.3333333 297.3333333 0.343893384 0.168383798 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319800 319800 'Slc22a30' mRNA 0 1 0 0 0.03 0 0.05 0 0 0.01 0.016666667 2.2 0 0 0.333333333 0.733333333 0.863090843 0.855208319 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0015301///anion:anion antiporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015636///short-chain fatty acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015711///organic anion transport+++GO:0015912///short-chain fatty acid transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport 319801 319801 'Tigar' mRNA 219.86 222.66 172.21 1.79 1.79 1.51 2.33 1.84 2.33 1.696666667 2.166666667 323.04 240.54 303.62 204.91 289.0666667 0.006736497 0.488977572 00051///Fructose and mannose metabolism+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0004083///bisphosphoglycerate 2-phosphatase activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0016787///hydrolase activity" "GO:0002931///response to ischemia+++GO:0006003///fructose 2,6-bisphosphate metabolic process+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009410///response to xenobiotic stimulus+++GO:0010332///response to gamma radiation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0016311///dephosphorylation+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0033673///negative regulation of kinase activity+++GO:0043069///negative regulation of programmed cell death+++GO:0043456///regulation of pentose-phosphate shunt+++GO:0045739///positive regulation of DNA repair+++GO:0045820///negative regulation of glycolytic process+++GO:0060576///intestinal epithelial cell development+++GO:0071279///cellular response to cobalt ion+++GO:0071456///cellular response to hypoxia+++GO:1901215///negative regulation of neuron death+++GO:1901525///negative regulation of mitophagy+++GO:1902153///regulation of response to DNA damage checkpoint signaling+++GO:1903301///positive regulation of hexokinase activity+++GO:1904024///negative regulation of glucose catabolic process to lactate via pyruvate+++GO:2000378///negative regulation of reactive oxygen species metabolic process" 319804 319804 'Glt1d1' mRNA 1 0 0 0.07 0 0 0.12 0.17 0.25 0.023333333 0.18 4 5 4 0.333333333 4.333333333 0.082360225 3.586523089 GO:0005576///extracellular region+++GO:0005829///cytosol "GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0008150///biological_process 319807 319807 'Nwd2' mRNA 199.54 212.36 173.15 0.85 0.89 0.78 0.48 0.48 0.54 0.84 0.5 131.5 126.89 142.6 195.0166667 133.6633333 0.00538893 -0.55823603 GO:0005575///cellular_component 319817 319817 'Rc3h2' mRNA 1244 1117 888 7.27 6.41 5.51 6.12 5.8 6.93 6.396666667 6.283333333 1207 1117 1323 1083 1215.666667 0.186697851 0.160005076 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0035613///RNA stem-loop binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0001782///B cell homeostasis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0035264///multicellular organism growth+++GO:0042098///T cell proliferation+++GO:0043029///T cell homeostasis+++GO:0043488///regulation of mRNA stability+++GO:0048286///lung alveolus development+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0050852///T cell receptor signaling pathway+++GO:0060173///limb development+++GO:0061470///T follicular helper cell differentiation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000628///regulation of miRNA metabolic process" 319822 319822 'Smyd4' mRNA 376.42 379.69 338.66 5.92 5.84 5.62 4.05 4.19 3.99 5.793333333 4.076666667 299.83 303.51 283.95 364.9233333 295.7633333 0.031844249 -0.314522825 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0007507///heart development+++GO:0032259///methylation 319832 319832 'Tmem229a' mRNA 604 704 319 6.47 7.42 3.63 2.5 3.49 3.66 5.84 3.216666667 269 366 381 542.3333333 338.6666667 0.082837802 -0.671435857 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319845 319845 'Bbs9' mRNA 772 782 730 13.97 13.57 14.55 6.86 7.27 7.97 14.03 7.366666667 413 421 465 761.3333333 433 4.17E-14 -0.824788163 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0034451///centriolar satellite+++GO:0034464///BBSome+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0005515///protein binding GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0045444///fat cell differentiation+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium 319875 319875 'Tmprss11b' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 319876 319876 'Cobll1' mRNA 1480 1422 1294 15.56 14.78 14.45 11.44 10.28 10.92 14.93 10.88 1242 1092 1158 1398.666667 1164 0.001082782 -0.275998816 GO:0003785///actin monomer binding 319880 319880 'Tmcc3' mRNA 781 753 755 7.32 6.91 7.45 7.28 7.2 6.53 7.226666667 7.003333333 882 852 763 763 832.3333333 0.342643457 0.112840997 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding+++GO:0071889///14-3-3 protein binding GO:0007029///endoplasmic reticulum organization+++GO:0008150///biological_process+++GO:0016197///endosomal transport+++GO:0090148///membrane fission+++GO:0097750///endosome membrane tubulation 319885 319885 'Zcchc7' mRNA 1091 1112 1117 24.04 24.13 26.04 18.75 16.88 17.73 24.73666667 17.78666667 980 861 896 1106.666667 912.3333333 0.002024748 -0.292366743 03018///RNA degradation GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 319887 319887 'E030030I06Rik' mRNA 97.21 88.57 76.31 2.72 2.51 2.25 1.77 1.93 1.94 2.493333333 1.88 67.47 73.47 73.75 87.36333333 71.56333333 0.347739005 -0.301111211 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319888 319888 'Oacyl' mRNA 80 79 94 1.21 1.23 1.57 0.25 0.1 0.26 1.336666667 0.203333333 23 7 18 84.33333333 16 4.44E-09 -2.420076731 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0008150///biological_process 319899 319899 'Dock6' mRNA 2054 2109 1655 20.22 20.8 16.91 15.5 13.97 17.38 19.31 15.61666667 1806 1686 1934 1939.333333 1808.666667 0.272951553 -0.108035376 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 319901 319901 'Dsel' mRNA 425 472 448 3.95 4.34 4.44 4.59 3.81 3.58 4.243333333 3.993333333 562 459 425 448.3333333 482 0.600841841 0.090295051 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016853///isomerase activity+++GO:0047757///chondroitin-glucuronate 5-epimerase activity GO:0030204///chondroitin sulfate metabolic process+++GO:0030205///dermatan sulfate metabolic process 319909 319909 'Ism1' mRNA 127 118 106 1.88 1.89 1.84 4.25 3.66 3.39 1.87 3.766666667 296 247 243 117 262 5.04E-10 1.151648588 GO:0005576///extracellular region GO:0016525///negative regulation of angiogenesis 319922 319922 'Vwc2' mRNA 7 8 9 0.11 0.1 0.1 0 0.01 0 0.103333333 0.003333333 0 1 0 8 0.333333333 0.008845455 -4.497421603 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse GO:0003674///molecular_function GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045666///positive regulation of neuron differentiation 319924 319924 'Apba1' mRNA 3760 3423 2535 30.73 27.5 22.01 2.46 2.35 2.56 26.74666667 2.456666667 348 324 353 3239.333333 341.6666667 3.03E-198 -3.249985164 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine+++GO:0048471///perinuclear region of cytoplasm+++GO:0048787///presynaptic active zone membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse "GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0030165///PDZ domain binding+++GO:0044877///protein-containing complex binding" GO:0001701///in utero embryonic development+++GO:0006886///intracellular protein transport+++GO:0007268///chemical synaptic transmission+++GO:0007626///locomotory behavior+++GO:0010468///regulation of gene expression+++GO:0014047///glutamate secretion+++GO:0014051///gamma-aminobutyric acid secretion+++GO:0015031///protein transport+++GO:0035264///multicellular organism growth+++GO:0065003///protein-containing complex assembly+++GO:2000300///regulation of synaptic vesicle exocytosis 319929 319929 'A630076J17Rik' mRNA 11.73 8.89 10.15 1.28 0.97 1.18 0.81 0.7 0.58 1.143333333 0.696666667 8.46 7.07 5.87 10.25666667 7.133333333 0.604564605 -0.551935293 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 319934 319934 'Sbf2' mRNA 519 550 539 3.82 4.02 4.24 3.84 3.62 4.14 4.026666667 3.866666667 598 552 624 536 591.3333333 0.333735566 0.128986167 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019208///phosphatase regulator activity+++GO:0019902///phosphatase binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding GO:0006914///autophagy+++GO:0043087///regulation of GTPase activity 319939 319939 'Tns3' mRNA 1355 1377 902 9.92 9.86 6.97 7.49 6.48 7.08 8.916666667 7.016666667 1224 1047 1128 1211.333333 1133 0.492918508 -0.10081444 GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0016791///phosphatase activity GO:0008284///positive regulation of cell proliferation+++GO:0016311///dephosphorylation+++GO:0016477///cell migration+++GO:0035556///intracellular signal transduction+++GO:0048286///lung alveolus development 319942 319942 'A530016L24Rik' mRNA 70 107 124 1.49 2.22 2.79 0.18 0.17 0.06 2.166666667 0.136666667 10 9 3 100.3333333 7.333333333 7.45E-16 -3.795626006 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319944 319944 'Taf2' mRNA 675 621 411 7.27 6.58 4.68 3.96 5.83 6.51 6.176666667 5.433333333 426 609 673 569 569.3333333 0.998591786 0.002084626 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0033276///transcription factor TFTC complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0014070///response to organic cyclic compound 319945 319945 'Flad1' mRNA 1204 1323 1178 30.62 33.1 31.69 21.48 20.77 18.5 31.80333333 20.25 978 920 813 1235 903.6666667 9.59E-07 -0.462013244 00740///Riboflavin metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003919///FMN adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042802///identical protein binding GO:0006747///FAD biosynthetic process 319953 319953 'Ttll1' mRNA 495 529 546 13.22 14.15 15.75 9.91 8.53 8.18 14.37333333 8.873333333 427 355 338.65 523.3333333 373.55 2.50E-04 -0.502773464 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0002395///immune response in nasopharyngeal-associated lymphoid tissue+++GO:0003351///epithelial cilium movement+++GO:0006464///cellular protein modification process+++GO:0007288///sperm axoneme assembly+++GO:0018095///protein polyglutamylation+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0035082///axoneme assembly 319955 319955 'Ercc6' mRNA 1570.36 1624.09 1442.62 9.74 9.87 9.5 4.75 4.53 4.62 9.703333333 4.633333333 883.12 823.19 832.66 1545.69 846.3233333 1.18E-28 -0.879798434 03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0008023///transcription elongation factor complex+++GO:0016604///nuclear body+++GO:0090734///site of DNA damage GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0030296///protein tyrosine kinase activator activity+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0070063///RNA polymerase binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000012///single strand break repair+++GO:0000077///DNA damage checkpoint+++GO:0000303///response to superoxide+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006284///base-excision repair+++GO:0006290///pyrimidine dimer repair+++GO:0006338///chromatin remodeling+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007254///JNK cascade+++GO:0007256///activation of JNKK activity+++GO:0007257///activation of JUN kinase activity+++GO:0007399///nervous system development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009411///response to UV+++GO:0009636///response to toxic substance+++GO:0010165///response to X-ray+++GO:0010224///response to UV-B+++GO:0010332///response to gamma radiation+++GO:0010628///positive regulation of gene expression+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0035264///multicellular organism growth+++GO:0042262///DNA protection+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045494///photoreceptor cell maintenance+++GO:0045739///positive regulation of DNA repair+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0097680///double-strand break repair via classical nonhomologous end joining+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining" 319965 319965 'Cc2d1b' mRNA 860 981 950 14.29 16.28 16.81 19.05 15.67 16.53 15.79333333 17.08333333 1316 1057 1092 930.3333333 1155 0.006273518 0.297144001 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 319974 319974 'Auts2' mRNA 2059 2046 1514 14.91 14.56 11.63 4.46 4.1 4.52 13.7 4.36 710 637 697 1873 681.3333333 3.07E-49 -1.46511779 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0001764///neuron migration+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0031532///actin cytoskeleton reorganization+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048675///axon extension+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0060013///righting reflex+++GO:0097484///dendrite extension+++GO:0098582///innate vocalization behavior+++GO:2000620///positive regulation of histone H4-K16 acetylation 319984 319984 'Jph4' mRNA 5 4 2 0.06 0.05 0.03 0.1 0.05 0.06 0.046666667 0.07 10 5 6 3.666666667 7 0.470188862 0.926217165 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030314///junctional membrane complex+++GO:0043198///dendritic shaft GO:0001817///regulation of cytokine production+++GO:0007612///learning+++GO:0048167///regulation of synaptic plasticity+++GO:0050885///neuromuscular process controlling balance+++GO:2001256///regulation of store-operated calcium entry 319991 319991 'Kif6' mRNA 466 521 440 6.88 7.61 6.82 0.98 1.1 1.44 7.103333333 1.173333333 80 82 114 475.6666667 92 2.33E-43 -2.379137692 GO:0001673///male germ cell nucleus+++GO:0005871///kinesin complex+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement 319996 319996 'Golm2' mRNA 675.33 757.68 741.35 9.04 9.92 10.45 11.34 11.43 12.64 9.803333333 11.80333333 969.21 953.47 1045.18 724.7866667 989.2866667 2.35E-05 0.43663461 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 319997 319997 'A630001G21Rik' mRNA 7 13 19 0.24 0.5 0.72 4.37 4.32 3.98 0.486666667 4.223333333 139 134 123 13 132 7.80E-20 3.325418073 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 319998 319998 'Tmem198' mRNA 131 137 127 3.38 3.49 3.48 0.54 0.67 0.6 3.45 0.603333333 24 29 26 131.6666667 26.33333333 2.60E-15 -2.332173437 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway 320007 320007 'Sidt1' mRNA 13 14 18 0.16 0.17 0.24 0.32 0.27 0.17 0.19 0.253333333 29 24 15 15 22.66666667 0.398600877 0.575177294 GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0015485///cholesterol binding+++GO:0051033///RNA transmembrane transporter activity GO:0050658///RNA transport 320011 320011 'Uggt1' mRNA 1617 1699 1587 9.4 9.7 9.78 12.53 11.95 12.59 9.626666667 12.35666667 2484 2315 2418 1634.333333 2405.666667 9.30E-16 0.545932015 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0032991///protein-containing complex "GO:0003980///UDP-glucose:glycoprotein glucosyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0051082///unfolded protein binding" GO:0006486///protein glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0097359///UDP-glucosylation 320022 320022 'Terb1' mRNA 24 33 34 0.34 0.54 0.62 0.22 0.13 0.12 0.5 0.156666667 17 10 8 30.33333333 11.66666667 0.017630111 -1.398732824 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0070187///shelterin complex" GO:0005515///protein binding GO:0007129///synapsis+++GO:0045141///meiotic telomere clustering+++GO:0051321///meiotic cell cycle+++GO:0070197///meiotic attachment of telomere to nuclear envelope 320024 320024 'Nceh1' mRNA 2902 3077 2900 35.66 37.17 37.8 29.02 25.34 28.38 36.87666667 27.58 2715 2318 2575 2959.666667 2536 0.001234468 -0.235810874 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome+++04976///Bile secretion+++04979///Cholesterol metabolism GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016787///hydrolase activity+++GO:0017171///serine hydrolase activity+++GO:0042301///phosphate ion binding+++GO:0052689///carboxylic ester hydrolase activity GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0016042///lipid catabolic process+++GO:0046485///ether lipid metabolic process+++GO:0060395///SMAD protein signal transduction 320027 320027 'Fstl4' mRNA 953 968 976 9.92 9.91 10.78 1.82 1.88 1.11 10.20333333 1.603333333 181 174 122 965.6666667 159 2.07E-81 -2.616294856 GO:0005576///extracellular region+++GO:0030141///secretory granule GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0048403///brain-derived neurotrophic factor binding GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030517///negative regulation of axon extension+++GO:0031549///negative regulation of brain-derived neurotrophic factor receptor signaling pathway+++GO:0048670///regulation of collateral sprouting+++GO:0048671///negative regulation of collateral sprouting+++GO:0061000///negative regulation of dendritic spine development 320040 320040 'Rnf222' mRNA 49 53 66 0.86 1.05 1.38 1.32 1.18 1.42 1.096666667 1.306666667 84 71 82 56 79 0.158589695 0.478050515 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding 320051 320051 'Exph5' mRNA 252 229 275 1.6 1.38 1.91 1.18 0.97 1.33 1.63 1.16 241 197 252 252 230 0.495835303 -0.14864643 GO:0005768///endosome GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0003334///keratinocyte development+++GO:0006886///intracellular protein transport+++GO:0045921///positive regulation of exocytosis+++GO:0050714///positive regulation of protein secretion+++GO:0071985///multivesicular body sorting pathway 320078 320078 'Olfml2b' mRNA 125 105 100 2.21 1.83 1.87 2.1 1.62 2.21 1.97 1.976666667 137 103 139 110 126.3333333 0.520365848 0.187975635 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0042802///identical protein binding+++GO:0050840///extracellular matrix binding GO:0030198///extracellular matrix organization 320080 320080 'Zbtb39' mRNA 198 170 128 1.76 1.49 1.21 0.99 0.99 1.04 1.486666667 1.006666667 128 125 130 165.3333333 127.6666667 0.109428293 -0.378577764 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 320091 320091 'Ano4' mRNA 1237 1342 1169 16.32 17.22 16.58 3.28 3.07 3.39 16.70666667 3.246666667 305 289 323 1249.333333 305.6666667 1.86E-91 -2.041330478 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity+++GO:0046983///protein dimerization activity GO:0006821///chloride transport+++GO:0006869///lipid transport+++GO:0055085///transmembrane transport+++GO:0061588///calcium activated phospholipid scrambling+++GO:0061589///calcium activated phosphatidylserine scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:1902476///chloride transmembrane transport 320095 320095 '6430550D23Rik' mRNA 35 39 48 1.06 1.2 1.61 1.09 1.5 1.15 1.29 1.246666667 38 55 40 40.66666667 44.33333333 0.848919683 0.109803887 GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity" 320100 320100 'Relt' mRNA 1081 1090 1122 20.64 20.58 22.64 6.47 6.52 5.26 21.28666667 6.083333333 387 380 304 1097.666667 357 2.01E-46 -1.634331704 04060///Cytokine-cytokine receptor interaction GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0006915///apoptotic process+++GO:0012501///programmed cell death+++GO:0097186///amelogenesis 320106 320106 'Slc38a11' mRNA 53.53 46.76 40.81 0.85 0.79 0.63 0.67 0.53 0.58 0.756666667 0.593333333 46.33 37.73 34.36 47.03333333 39.47333333 0.58403848 -0.259071258 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport 320111 320111 'Prr18' mRNA 23.93 23.67 6.78 0.34 0.37 0.12 0.23 0.12 0.23 0.276666667 0.193333333 18.8 9.85 17.58 18.12666667 15.41 0.802353909 -0.236244881 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320116 320116 'Fndc9' mRNA 5.6 0 2.28 0.14 0 0.06 0.02 0.02 0 0.066666667 0.013333333 1.13 1.12 0 2.626666667 0.75 0.499555297 -1.823683953 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320118 320118 'Fbxl13' mRNA 29 55 37 0.59 1.06 0.76 0.08 0.14 0.17 0.803333333 0.13 4 8 10 40.33333333 7.333333333 2.81E-05 -2.463548186 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 320119 320119 'Rps6kc1' mRNA 393 496 490 5.39 6.72 7.23 5.36 4.46 5.11 6.446666667 4.976666667 462 375 395 459.6666667 410.6666667 0.285155639 -0.178504441 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035091///phosphatidylinositol binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 320127 320127 'Dgki' mRNA 94 93 82 0.36 0.36 0.32 0.3 0.21 0.19 0.346666667 0.233333333 93.98 62 61.01 89.66666667 72.33 0.317487732 -0.329873894 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098891///extrinsic component of presynaptic active zone membrane+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005095///GTPase inhibitor activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding "GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0007269///neurotransmitter secretion+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0043087///regulation of GTPase activity+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046834///lipid phosphorylation+++GO:0046959///habituation+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:1900452///regulation of long-term synaptic depression+++GO:2000300///regulation of synaptic vesicle exocytosis" 320129 320129 'Grk3' mRNA 744 830 763 6 6.58 6.53 2.14 2.23 2.49 6.37 2.286666667 305 312 345 779 320.6666667 9.45E-29 -1.291609262 04062///Chemokine signaling pathway+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04724///Glutamatergic synapse+++04740///Olfactory transduction+++04745///Phototransduction - fly+++05032///Morphine addiction GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030424///axon+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044292///dendrite terminus+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097225///sperm midpiece GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004703///G protein-coupled receptor kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031748///D1 dopamine receptor binding+++GO:0047696///beta-adrenergic receptor kinase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0016310///phosphorylation+++GO:0031623///receptor internalization+++GO:0043647///inositol phosphate metabolic process+++GO:0046154///rhodopsin metabolic process 320135 320135 'BC049715' mRNA 4.21 3.23 3.14 0.11 0.05 0.06 0.19 0.15 0.05 0.073333333 0.13 6.23 6.41 4.25 3.526666667 5.63 0.651465198 0.66732203 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320139 320139 'Ptpn7' mRNA 18.59 24.96 21 0.31 0.39 0.36 5.26 4.84 4.48 0.353333333 4.86 370.07 332.5 303.01 21.51666667 335.1933333 2.01E-56 3.983605149 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0072686///mitotic spindle GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 320145 320145 'Sp8' mRNA 3 5 2 0.04 0.06 0.03 0.02 0 0.03 0.043333333 0.016666667 2 0 3 3.333333333 1.666666667 0.623000755 -1.003684915 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0030326///embryonic limb morphogenesis 320148 320148 'B430306N03Rik' mRNA 16 29.67 37 0.25 0.46 0.62 8.53 7.68 7.44 0.443333333 7.883333333 622.95 547.68 526.46 27.55666667 565.6966667 2.68E-86 4.353254578 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity 320150 320150 'Zdhhc17' mRNA 760 689 710 8.91 7.93 8.78 6.75 6.03 6.38 8.54 6.386666667 662 578 612 719.6666667 617.3333333 0.040830226 -0.234593304 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016235///aggresome+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse "GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0042802///identical protein binding" GO:0007409///axonogenesis+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0042953///lipoprotein transport+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1903830///magnesium ion transmembrane transport 320158 320158 'Zmat4' mRNA 1863.62 1966.82 1884.86 16.71 17.88 18.76 2.69 2.78 2.78 17.78333333 2.75 360.6 352 356.67 1905.1 356.4233333 5.74E-164 -2.431516217 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding 320159 320159 'Togaram2' mRNA 28 13 12 0.43 0.25 0.19 0.14 0.07 0.32 0.29 0.176666667 9 5 24 17.66666667 12.66666667 0.602609168 -0.483898612 GO:0005815///microtubule organizing center+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0072686///mitotic spindle GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0090307///mitotic spindle assembly 320162 320162 'Cep95' mRNA 372.53 390.15 358 8.3 8.59 8.33 5.31 4.65 5.36 8.406666667 5.106666667 282.32 238.36 270.32 373.56 263.6666667 3.88E-04 -0.5156019 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 320165 320165 'Tacc1' mRNA 4068 4245 4419 33.53 34.41 38.96 31.8 31.92 29.49 35.63333333 31.07 4474 4401 4068 4244 4314.333333 0.925253554 0.009349931 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0016922///nuclear receptor binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035259///glucocorticoid receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding "GO:0000226///microtubule cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0008283///cell proliferation+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0022027///interkinetic nuclear migration+++GO:0032886///regulation of microtubule-based process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division" 320181 320181 'Fndc7' mRNA 3877 4124 3956 48.81 51.88 51.79 20.69 20.36 20.73 50.82666667 20.59333333 1642 1632 1663 3985.666667 1645.666667 4.96E-86 -1.288253948 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 320183 320183 'Msrb3' mRNA 1509 1407 1366 23.55 21.86 21.73 7.84 6.31 7.55 22.38 7.233333333 589 482 556 1427.333333 542.3333333 3.09E-50 -1.408680778 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum "GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0033743///peptide-methionine (R)-S-oxide reductase activity+++GO:0033745///L-methionine-(R)-S-oxide reductase activity+++GO:0046872///metal ion binding" GO:0006979///response to oxidative stress+++GO:0030091///protein repair 320184 320184 'Lrrc58' mRNA 4390.36 4227.04 3707.01 26.84 25.4 24.04 23.15 22.19 23.66 25.42666667 23 4360.91 4084.98 4318.11 4108.136667 4254.666667 0.606283645 0.040813956 GO:0005575///cellular_component GO:0003674///molecular_function 320191 320191 'Hook3' mRNA 1171.09 1032.2 968.29 6.83 6.23 6.35 7.41 7.17 6.62 6.47 7.066666667 1257 1197.73 1194.31 1057.193333 1216.346667 0.044486844 0.191784688 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030897///HOPS complex+++GO:0034451///centriolar satellite+++GO:0070695///FHF complex GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0034452///dynactin binding+++GO:0042802///identical protein binding+++GO:0045503///dynein light chain binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0022027///interkinetic nuclear migration+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0034454///microtubule anchoring at centrosome+++GO:0045022///early endosome to late endosome transport+++GO:0050768///negative regulation of neurogenesis+++GO:0051645///Golgi localization+++GO:0071539///protein localization to centrosome+++GO:0097150///neuronal stem cell population maintenance+++GO:1905719///protein localization to perinuclear region of cytoplasm 320204 320204 'Etfbkmt' mRNA 930.03 979.44 959.85 28.48 30.74 30.87 38.74 34.58 35.26 30.03 36.19333333 1439.2 1316.02 1317.83 956.44 1357.683333 9.72E-09 0.492586928 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0031072///heat shock protein binding GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation+++GO:1904733///negative regulation of electron transfer activity+++GO:1904736///negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase 320207 320207 'Pik3r5' mRNA 47.83 57.01 38 0.6 0.7 0.51 8.05 7.05 7.24 0.603333333 7.446666667 745 643.94 645.99 47.61333333 678.31 3.89E-105 3.829876904 04022///cGMP-PKG signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++04611///Platelet activation+++04725///Cholinergic synapse+++04921///Oxytocin signaling pathway+++05145///Toxoplasmosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005944///phosphatidylinositol 3-kinase complex, class IB+++GO:0016020///membrane+++GO:0034451///centriolar satellite" GO:0016301///kinase activity+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0051897///positive regulation of protein kinase B signaling 320208 320208 'Tmem91' mRNA 42.68 45.41 51.13 2.18 3.19 3.05 0.82 1.1 0.93 2.806666667 0.95 29.96 25.95 25.95 46.40666667 27.28666667 0.058472828 -0.821512089 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 320209 320209 'Ddx11' mRNA 117.87 100.05 102.8 1.74 1.42 1.54 2.61 2.63 2.85 1.566666667 2.696666667 210.58 199.28 212.05 106.9066667 207.3033333 2.04E-06 0.949396786 GO:0000785///chromatin+++GO:0000922///spindle pole+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0030892///mitotic cohesin complex+++GO:0031390///Ctf18 RFC-like complex+++GO:0070062///extracellular exosome "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008186///RNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0043139///5'-3' DNA helicase activity+++GO:0045142///triplex DNA binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0051880///G-quadruplex DNA binding" GO:0006139///nucleobase-containing compound metabolic process+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007062///sister chromatid cohesion+++GO:0007275///multicellular organism development+++GO:0031297///replication fork processing+++GO:0032079///positive regulation of endodeoxyribonuclease activity+++GO:0032091///negative regulation of protein binding+++GO:0032508///DNA duplex unwinding+++GO:0034085///establishment of sister chromatid cohesion+++GO:0035563///positive regulation of chromatin binding+++GO:0044806///G-quadruplex DNA unwinding+++GO:0045876///positive regulation of sister chromatid cohesion+++GO:0072711///cellular response to hydroxyurea+++GO:0072719///cellular response to cisplatin+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1904976///cellular response to bleomycin+++GO:1990700///nucleolar chromatin organization+++GO:2000781///positive regulation of double-strand break repair 320213 320213 'Senp5' mRNA 680.6 742.84 641.87 5.62 6.14 5.79 6.27 5.7 5.96 5.85 5.976666667 851.61 742.14 762.9 688.4366667 785.55 0.103622965 0.179910419 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016929///SUMO-specific protease activity+++GO:0019783///ubiquitin-like protein-specific protease activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0007049///cell cycle+++GO:0016926///protein desumoylation+++GO:0051301///cell division 320214 320214 'Maats1' mRNA 952 953 937 19.03 18.75 19.86 1.49 1.51 1.42 19.21333333 1.473333333 86 85 79 947.3333333 83.33333333 2.29E-142 -3.519305874 GO:0001536///radial spoke stalk+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0008150///biological_process 320225 320225 'Catsperg1' mRNA 107.4 107.7 98.35 1.12 1.05 1.12 0.81 0.7 0.63 1.096666667 0.713333333 84.67 74.99 69.62 104.4833333 76.42666667 0.090495842 -0.470509119 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0097228///sperm principal piece GO:0003674///molecular_function GO:0008150///biological_process 320226 320226 'Ccdc171' mRNA 225 209 201 2.53 2.72 2.74 1.5 1.99 1.81 2.663333333 1.766666667 135 146 130 211.6666667 137 9.25E-04 -0.638092386 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320234 320234 'Ccdc66' mRNA 512.91 580.68 602.01 8.94 10.51 11.01 8.61 7.33 7.06 10.15333333 7.666666667 573.6 468.9 454.19 565.2 498.8966667 0.187206897 -0.196674988 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030054///cell junction+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0090543///Flemming body GO:0008017///microtubule binding+++GO:0042803///protein homodimerization activity GO:0001578///microtubule bundle formation+++GO:0001895///retina homeostasis+++GO:0030030///cell projection organization+++GO:0046548///retinal rod cell development+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060060///post-embryonic retina morphogenesis in camera-type eye+++GO:0060271///cilium assembly+++GO:1903564///regulation of protein localization to cilium 320237 320237 'Smim10l2a' mRNA 370 364 336 6.47 6.26 6.23 2.14 2.18 2.57 6.32 2.296666667 141 140 164 356.6666667 148.3333333 1.46E-15 -1.276042976 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320244 320244 'Ttll5' mRNA 607.23 658.02 635.1 6.99 7.2 7.38 5.01 3.95 4.65 7.19 4.536666667 514.06 424.03 462.07 633.45 466.72 1.44E-04 -0.454345952 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097731///9+0 non-motile cilium GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0009566///fertilization+++GO:0018095///protein polyglutamylation+++GO:0030317///flagellated sperm motility+++GO:0060041///retina development in camera-type eye 320253 320253 'Marchf3' mRNA 134 100 123 4.26 3.17 4.19 4.23 3.28 4.19 3.873333333 3.9 153 116 148 119 139 0.46204033 0.208080667 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0016567///protein ubiquitination 320256 320256 'Dlec1' mRNA 322.67 331.92 294.55 2.36 2.37 2.06 1.35 1.31 1.32 2.263333333 1.326666667 234.4 227.64 226.62 316.38 229.5533333 0.002097074 -0.473348459 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding GO:0002357///defense response to tumor cell+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation 320265 320265 'Tafa1' mRNA 103 114 72 1.33 1.51 1.01 0.35 0.37 0.54 1.283333333 0.42 29 32 45 96.33333333 35.33333333 1.38E-05 -1.449228255 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0014016///neuroblast differentiation+++GO:1902692///regulation of neuroblast proliferation 320267 320267 'Fubp3' mRNA 1030 1088 1204 16.37 16.91 20.35 15.58 14.56 15.03 17.87666667 15.05666667 1136 1030 1039 1107.333333 1068.333333 0.607223091 -0.068079598 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 320271 320271 'Scai' mRNA 496 515 479 2.73 2.58 2.62 1.77 1.21 1.67 2.643333333 1.55 374 278 306 496.6666667 319.3333333 2.30E-06 -0.650745851 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003714///transcription corepressor activity+++GO:0005515///protein binding "GO:0006351///transcription, DNA-templated+++GO:0009968///negative regulation of signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated" 320277 320277 'Spef2' mRNA 848 763 734 12.93 11.8 12.26 1.85 1.69 1.51 12.33 1.683333333 127 118 92 781.6666667 112.3333333 1.46E-85 -2.810323738 GO:0002177///manchette+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097225///sperm midpiece GO:0005515///protein binding GO:0003351///epithelial cilium movement+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0030154///cell differentiation+++GO:0044458///motile cilium assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048854///brain morphogenesis+++GO:0060541///respiratory system development+++GO:0090660///cerebrospinal fluid circulation 320292 320292 'Rasgef1b' mRNA 673 659 575 12.35 11.9 11.19 13.19 14.42 12.86 11.81333333 13.49 827 883 781 635.6666667 830.3333333 4.09E-04 0.376545733 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0030496///midbody GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 320299 320299 'Iqcb1' mRNA 949.79 971.55 951.49 16.44 16.14 17.64 9.31 8.24 8.41 16.74 8.653333333 630.57 528.35 544.3 957.61 567.74 4.18E-14 -0.767985296 GO:0001750///photoreceptor outer segment+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0019899///enzyme binding GO:0030030///cell projection organization+++GO:0045494///photoreceptor cell maintenance+++GO:0048496///maintenance of animal organ identity+++GO:0060271///cilium assembly 320302 320302 'Glt28d2' mRNA 509 473 488 10.28 9.41 10.46 5.27 5.02 5.3 10.05 5.196666667 300 279 292 490 290.3333333 3.64E-09 -0.768029427 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis "GO:0004577///N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006488///dolichol-linked oligosaccharide biosynthetic process 320309 320309 '1520401A03Rik' mRNA 2 7 4 0.03 0.12 0.06 0.02 0.02 0.07 0.07 0.036666667 1 1 4 4.333333333 2 0.518275099 -1.119531197 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320311 320311 'Rnf152' mRNA 1106 1199 944 6.96 7.43 6.25 3.43 3.43 3.39 6.88 3.416666667 623 609 599 1083 610.3333333 7.75E-18 -0.835313442 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031301///integral component of organelle membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006915///apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0034198///cellular response to amino acid starvation+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:1904262///negative regulation of TORC1 signaling 320332 320332 'H4f16' mRNA 14 21 17 2.97 4.47 3.83 3.18 2.32 0.97 3.756666667 2.156666667 17 12 5 17.33333333 11.33333333 0.439208749 -0.628296504 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 320333 320333 'D830030K20Rik' mRNA 13.56 14.39 4 0.42 0.49 0.17 0.21 0.11 0.28 0.36 0.2 6.99 8.09 10.19 10.65 8.423333333 0.75009672 -0.35918512 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320343 320343 'Lypd6' mRNA 596 618 597 9.21 9.37 9.77 6.4 7.29 6.41 9.45 6.7 477 532 461 603.6666667 490 0.011548907 -0.312124349 04080///Neuroactive ligand-receptor interaction GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0045202///synapse GO:0030548///acetylcholine receptor regulator activity+++GO:0030550///acetylcholine receptor inhibitor activity GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 320351 320351 'Tmem251' mRNA 213 234 194 14.45 16.03 15.62 22.24 28.89 23.97 15.36666667 25.03333333 351 434 362 213.6666667 382.3333333 1.68E-07 0.832037726 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320352 320352 'Lrrc31' mRNA 12.26 8.87 9.85 0.33 0.24 0.28 0.24 0.25 0.24 0.283333333 0.243333333 10.1 10.56 9.72 10.32666667 10.12666667 0.998257897 -0.011403728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320360 320360 'Ric3' mRNA 414.93 364.7 340.76 4.44 3.8 3.8 0.82 0.79 0.86 4.013333333 0.823333333 82 82 81 373.4633333 81.66666667 9.33E-36 -2.199997379 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0033130///acetylcholine receptor binding+++GO:0044183///protein binding involved in protein folding "GO:0006457///protein folding+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007271///synaptic transmission, cholinergic+++GO:0034394///protein localization to cell surface+++GO:0034622///cellular protein-containing complex assembly+++GO:2000010///positive regulation of protein localization to cell surface" 320365 320365 'Fry' mRNA 918 930 844 4.46 4.44 4.35 2.66 2.72 2.57 4.416666667 2.65 631 630 590 897.3333333 617 1.22E-08 -0.550856927 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030427///site of polarized growth GO:0004857///enzyme inhibitor activity GO:0000902///cell morphogenesis+++GO:0031175///neuron projection development+++GO:0043086///negative regulation of catalytic activity+++GO:1904428///negative regulation of tubulin deacetylation 320376 320376 'Bcorl1' mRNA 226 191 185 1.7 1.43 1.41 1.5 1.26 1.5 1.513333333 1.42 228 184 223 200.6666667 211.6666667 0.796280494 0.065218326 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0006325///chromatin organization+++GO:0008150///biological_process 320394 320394 'Cenpt' mRNA 227 196 194 7.18 5.53 5.97 9.03 9.91 9.77 6.226666667 9.57 339 371 369 205.6666667 359.6666667 2.90E-07 0.796334939 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body" GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051382///kinetochore assembly+++GO:1903394///protein localization to kinetochore involved in kinetochore assembly 320398 320398 'Lrig3' mRNA 70 90 74 0.93 1.18 1.05 0.83 0.89 0.69 1.053333333 0.803333333 72 75 58 78 68.33333333 0.586946668 -0.200919504 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0007275///multicellular organism development+++GO:0032474///otolith morphogenesis 320404 320404 'Itpkb' mRNA 1176 1145 588 12.69 12.75 7.87 6.45 5.64 5.89 11.10333333 5.993333333 615 539 567 969.6666667 573.6666667 0.01323396 -0.755476854 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0005524///ATP binding+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity" GO:0000165///MAPK cascade+++GO:0001932///regulation of protein phosphorylation+++GO:0002262///myeloid cell homeostasis+++GO:0007166///cell surface receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0030217///T cell differentiation+++GO:0032957///inositol trisphosphate metabolic process+++GO:0032958///inositol phosphate biosynthetic process+++GO:0033030///negative regulation of neutrophil apoptotic process+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0045059///positive thymic T cell selection+++GO:0045061///thymic T cell selection+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0071277///cellular response to calcium ion 320405 320405 'Cadps2' mRNA 230 271 189 2.58 2.95 2.31 0.52 0.35 0.26 2.613333333 0.376666667 57 36 27 230 40 5.00E-22 -2.532918124 GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0046872///metal ion binding GO:0006887///exocytosis+++GO:0009267///cellular response to starvation+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0016082///synaptic vesicle priming+++GO:0045921///positive regulation of exocytosis+++GO:0061484///hematopoietic stem cell homeostasis+++GO:1990504///dense core granule exocytosis 320407 320407 'Klri2' mRNA 0 1.62 5 0 0.02 0.07 0.02 0.06 0.01 0.03 0.03 2 5 1 2.206666667 2.666666667 0.866309468 0.366381299 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004888///transmembrane signaling receptor activity+++GO:0030246///carbohydrate binding GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0008150///biological_process+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 320415 320415 'Gchfr' mRNA 354 307 331 42.08 36.31 41.77 19.58 18.53 17.82 40.05333333 18.64333333 188 173 165 330.6666667 175.3333333 1.08E-08 -0.928883807 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex+++GO:0042470///melanosome GO:0004857///enzyme inhibitor activity+++GO:0016597///amino acid binding+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030742///GTP-dependent protein binding+++GO:0044549///GTP cyclohydrolase binding+++GO:0044877///protein-containing complex binding GO:0009890///negative regulation of biosynthetic process+++GO:0043105///negative regulation of GTP cyclohydrolase I activity+++GO:0065003///protein-containing complex assembly 320429 320429 'Trank1' mRNA 12 14 12 0.06 0.07 0.07 0 0.02 0.01 0.066666667 0.01 1 4 2 12.66666667 2.333333333 0.018218733 -2.444874854 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320435 320435 'Rinl' mRNA 93 90 85 1.72 1.7 1.72 7.3 6.57 6.89 1.713333333 6.92 438 385 400 89.33333333 407.6666667 4.72E-39 2.178267596 GO:0001726///ruffle+++GO:0015629///actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 320438 320438 'Alg6' mRNA 336 354 347 6.42 6.9 6.98 7.35 5.54 5.79 6.766666667 6.226666667 422 311 343 345.6666667 358.6666667 0.863090843 0.038294496 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0042281///dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity+++GO:0046527///glucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process 320452 320452 'P4ha3' mRNA 314 318 183 7.42 7.42 4.6 3.05 3.36 3.34 6.48 3.25 148 159 157 271.6666667 154.6666667 1.12E-04 -0.812923092 00330///Arginine and proline metabolism GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen "GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0019511///peptidyl-proline hydroxylation 320460 320460 'Vwc2l' mRNA 2 3 2 0.02 0.06 0.04 0 0 0 0.04 0 0 0 0 2.333333333 0 0.18180883 -3.671265478 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045666///positive regulation of neuron differentiation 320472 320472 'Ppm1e' mRNA 107 114 80 0.9 0.95 0.73 0.39 0.29 0.35 0.86 0.343333333 52 38 47 100.3333333 45.66666667 1.57E-04 -1.143062407 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006469///negative regulation of protein kinase activity+++GO:0006470///protein dephosphorylation+++GO:0035690///cellular response to drug+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0051496///positive regulation of stress fiber assembly+++GO:0071466///cellular response to xenobiotic stimulus 320473 320473 'Heatr5b' mRNA 554 599 571 4.56 4.84 4.98 4.36 3.95 3.8 4.793333333 4.036666667 610 541 515 574.6666667 555.3333333 0.684650159 -0.062473947 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030136///clathrin-coated vesicle+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding "GO:0006897///endocytosis+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi" 320484 320484 'Rasal3' mRNA 47 40 75 0.7 0.58 1.17 6.82 6.04 5.47 0.816666667 6.11 506 445 401 54 450.6666667 2.68E-45 3.038875233 04014///Ras signaling pathway GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0098562///cytoplasmic side of membrane GO:0005096///GTPase activator activity+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0051142///positive regulation of NK T cell proliferation 320487 320487 'Heatr5a' mRNA 421 358 338 2.84 2.38 2.42 3.29 2.9 3.27 2.546666667 3.153333333 561 484 539 372.3333333 528 1.74E-04 0.492977993 GO:0005829///cytosol+++GO:0030139///endocytic vesicle GO:0003674///molecular_function "GO:0006897///endocytosis+++GO:0008104///protein localization+++GO:0042147///retrograde transport, endosome to Golgi" 320492 320492 'A830018L16Rik' mRNA 43.55 38.13 34 0.57 0.46 0.37 0.11 0.12 0.13 0.466666667 0.12 15.21 13.09 16.4 38.56 14.9 0.004902452 -1.395770678 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320495 320495 'Ipcef1' mRNA 9 7 12 0.09 0.07 0.12 0.19 0.21 0.23 0.093333333 0.21 18 21 23 9.333333333 20.66666667 0.104473382 1.128543432 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0019904///protein domain specific binding 320502 320502 'Lmod3' mRNA 4 4 2 0.1 0.1 0.06 0.11 0.11 0.02 0.086666667 0.08 5 5 1 3.333333333 3.666666667 0.939090805 0.135165902 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0030016///myofibril+++GO:0031430///M band+++GO:0031672///A band GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding+++GO:0005523///tropomyosin binding GO:0006936///muscle contraction+++GO:0006941///striated muscle contraction+++GO:0007015///actin filament organization+++GO:0030239///myofibril assembly+++GO:0030240///skeletal muscle thin filament assembly+++GO:0045010///actin nucleation+++GO:0048741///skeletal muscle fiber development+++GO:0048743///positive regulation of skeletal muscle fiber development+++GO:0051694///pointed-end actin filament capping 320506 320506 'Lmbrd2' mRNA 253.93 257 176 1.96 1.88 1.39 1.12 1.35 1.93 1.743333333 1.466666667 168 184 268.35 228.9766667 206.7833333 0.585926433 -0.148641685 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0071875///adrenergic receptor signaling pathway 320508 320508 'Cachd1' mRNA 679 670 337 7.31 7.09 3.85 2.66 2.6 2.82 6.083333333 2.693333333 285 272 292 562 283 3.47E-07 -0.987452937 GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005245///voltage-gated calcium channel activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0070588///calcium ion transmembrane transport 320522 320522 'Bhlha9' mRNA 7 11 9 0.36 0.55 0.49 0.09 0.05 0.18 0.466666667 0.106666667 2 1 4 9 2.333333333 0.097156189 -1.959570858 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0032502///developmental process 320528 320528 'Vps13c' mRNA 625 607.15 569 2.31 2.22 2.21 3.2 2.57 3.06 2.246666667 2.943333333 982 768 901 600.3833333 883.6666667 5.90E-07 0.545030372 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0032127///dense core granule membrane GO:0003674///molecular_function GO:0006623///protein targeting to vacuole+++GO:0007005///mitochondrion organization+++GO:0032868///response to insulin+++GO:0045053///protein retention in Golgi apparatus+++GO:1905090///negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization 320534 320534 'Tmem104' mRNA 694 696 549 8.15 8.02 6.84 14.44 13.89 14.16 7.67 14.16333333 1416 1330 1344 646.3333333 1363.333333 4.08E-31 1.068663074 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320538 320538 'Ubn2' mRNA 1725.51 1907.02 1621.97 6.12 6.64 6.1 4.03 3.61 4.4 6.286666667 4.013333333 1307.92 1144.91 1385.52 1751.5 1279.45 1.12E-07 -0.463843093 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0006336///DNA replication-independent nucleosome assembly 320541 320541 'Slc35e2' mRNA 1284.85 1164.84 1150.34 10.58 9.31 10.14 6.83 5.5 6.04 10.01 6.123333333 950.51 752.46 819.69 1200.01 840.8866667 1.29E-07 -0.526575915 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity GO:0001835///blastocyst hatching+++GO:0055085///transmembrane transport 320554 320554 'Tcp11l1' mRNA 1141.93 1046.72 749.56 6.69 6.07 3.57 3.63 4.18 4.59 5.443333333 4.133333333 751.12 690.02 818.91 979.4033333 753.35 0.003328382 -0.382758928 GO:0005874///microtubule GO:0003674///molecular_function GO:0007165///signal transduction 320557 320557 'Fam169a' mRNA 219.53 259.9 209.48 1.88 2.31 1.74 0.88 0.83 0.85 1.976666667 0.853333333 121.15 110.89 114.25 229.6366667 115.43 1.59E-07 -1.003394276 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 320558 320558 'Sycp2' mRNA 1 3 1 0.01 0.03 0.01 0.02 0 0 0.016666667 0.006666667 2 0 0 1.666666667 0.666666667 0.669993744 -1.339508056 GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0005515///protein binding GO:0000080///mitotic G1 phase+++GO:0007049///cell cycle+++GO:0007140///male meiotic nuclear division+++GO:0007143///female meiotic nuclear division+++GO:0009566///fertilization+++GO:0009887///animal organ morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0048808///male genitalia morphogenesis+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0140013///meiotic nuclear division 320560 320560 'Dennd5b' mRNA 1095.81 1037.9 1173.38 5.91 5.46 6.69 1.9 1.92 2.09 6.02 1.97 408.31 402.93 435.81 1102.363333 415.6833333 5.29E-38 -1.423516157 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity+++GO:1905885///positive regulation of triglyceride transport 320563 320563 'Islr2' mRNA 1 0 0 0.01 0 0 0 0 0.01 0.003333333 0.003333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0045773///positive regulation of axon extension 320571 320571 'Atp8b5' mRNA 88 69 66 1.07 0.83 0.85 0.28 0.19 0.25 0.916666667 0.24 27 18 23 74.33333333 22.66666667 3.81E-06 -1.725231348 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity GO:0006869///lipid transport+++GO:0007030///Golgi organization+++GO:0015914///phospholipid transport+++GO:0045332///phospholipid translocation 320581 320581 'Idi2' mRNA 1 2 5 0.03 0.05 0.13 0 0 0 0.07 0 0 0 0 2.666666667 0 0.13645269 -3.900057995 00900///Terpenoid backbone biosynthesis GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0043231///intracellular membrane-bounded organelle GO:0004452///isopentenyl-diphosphate delta-isomerase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0009240///isopentenyl diphosphate biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0046490///isopentenyl diphosphate metabolic process+++GO:0050992///dimethylallyl diphosphate biosynthetic process 320587 320587 'Tmem88b' mRNA 165.17 153.25 182.98 2.59 2.36 3.04 3.97 3.47 3.29 2.663333333 3.576666667 291.41 248.51 233.77 167.1333333 257.8966667 0.001203811 0.609849247 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030165///PDZ domain binding GO:0008150///biological_process 320590 320590 'Svopl' mRNA 118 91 115 2.79 2.08 2.86 0.76 0.92 0.68 2.576666667 0.786666667 38 45 32 108 38.33333333 1.02E-06 -1.50897024 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 320595 320595 'Phf8' mRNA 855 888 849 7.96 8.34 8.35 5.99 5.51 5.25 8.216666667 5.583333333 727 652 630 864 669.6666667 1.83E-04 -0.380324428 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031965///nuclear membrane "GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005506///iron ion binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0035575///histone demethylase activity (H4-K20 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)+++GO:0071558///histone demethylase activity (H3-K27 specific)" "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0007049///cell cycle+++GO:0007420///brain development+++GO:0033169///histone H3-K9 demethylation+++GO:0035574///histone H4-K20 demethylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0061188///negative regulation of chromatin silencing at rDNA+++GO:0070544///histone H3-K36 demethylation+++GO:0071557///histone H3-K27 demethylation" 320604 320604 'Ccdc169' mRNA 6 6 1 0.16 0.12 0.03 0.07 0.1 0.04 0.103333333 0.07 2 6 2 4.333333333 3.333333333 0.850807944 -0.358494411 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320609 320609 'Strip2' mRNA 98 99 104 1.57 1.22 1.66 0.93 0.87 0.97 1.483333333 0.923333333 76 69 68 100.3333333 71 0.069667377 -0.513124866 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration 320615 320615 'Dop1a' mRNA 393.79 442.8 333.55 2.56 2.82 2.29 1.87 1.53 1.55 2.556666667 1.65 336.78 265.03 271.42 390.0466667 291.0766667 0.005798762 -0.43090951 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003674///molecular_function GO:0006895///Golgi to endosome transport+++GO:0015031///protein transport 320631 320631 'Abca15' mRNA 1 0 3 0.01 0 0.03 0 0 0 0.013333333 0 0 0 0 1.333333333 0 0.464551436 -2.917308793 02010///ABC transporters GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006869///lipid transport+++GO:0055085///transmembrane transport 320632 320632 'Snrnp200' mRNA 3909 4000 3796 30.57 30.75 31.48 15.65 14.04 14.39 30.93333333 14.69333333 2305 2021 2053 3901.666667 2126.333333 4.36E-43 -0.888448015 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0000388///spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 320633 320633 'Zbtb26' mRNA 211 241 244 2.11 2.37 2.59 1.63 1.81 1.62 2.356666667 1.686666667 187 203 180 232 190 0.124584609 -0.301223944 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 320634 320634 'Ocrl' mRNA 1496 1521 1390 15.15 15.15 14.96 10.69 10.5 10.44 15.08666667 10.54333333 1210 1176 1165 1469 1183.666667 3.64E-05 -0.322357136 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042995///cell projection "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0005096///GTPase activator activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0031267///small GTPase binding+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0052658///inositol-1,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity+++GO:0052745///inositol phosphate phosphatase activity" GO:0001701///in utero embryonic development+++GO:0007165///signal transduction+++GO:0030030///cell projection organization+++GO:0043087///regulation of GTPase activity+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0060271///cilium assembly 320635 320635 'Cyb5r2' mRNA 136 166 131 5.21 6.29 5.48 1.24 1.15 0.8 5.66 1.063333333 41 35 30 144.3333333 35.33333333 1.56E-13 -2.04030446 00520///Amino sugar and nucleotide sugar metabolism GO:0005739///mitochondrion+++GO:0016020///membrane "GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0016491///oxidoreductase activity+++GO:0071949///FAD binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0016126///sterol biosynthetic process 320640 320640 'Skint4' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 320655 320655 'Pgap3' mRNA 242 214 240 5.5 4.74 5.72 4.02 4.29 4.15 5.32 4.153333333 201 210 206 232 205.6666667 0.3569189 -0.187175873 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane "GO:0016788///hydrolase activity, acting on ester bonds" GO:0006505///GPI anchor metabolic process+++GO:0006506///GPI anchor biosynthetic process 320661 320661 'D5Ertd579e' mRNA 1305 1302 1147 10.12 9.9 9.51 7.33 7.11 7.15 9.843333333 7.196666667 1091 1031 1034 1251.333333 1052 0.002148113 -0.260417048 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 320662 320662 'Casc1' mRNA 361 358 328 5.64 5.77 5.62 0.67 1.06 0.76 5.676666667 0.83 50 75 56 349 60.33333333 2.12E-37 -2.540620303 GO:0005737///cytoplasm+++GO:0005858///axonemal dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0036156///inner dynein arm+++GO:0042995///cell projection GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding GO:0051012///microtubule sliding 320664 320664 'Cass4' mRNA 6 12 9 0.09 0.17 0.14 0.7 0.51 0.42 0.133333333 0.543333333 58 41 33 9 44 2.71E-05 2.275011621 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:1990782///protein tyrosine kinase binding GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016477///cell migration+++GO:0030335///positive regulation of cell migration+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0090527///actin filament reorganization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 320678 320678 'Iffo1' mRNA 523 602 473 10.07 11.41 9.66 8.84 8.35 6.94 10.38 8.043333333 529 487 403 532.6666667 473 0.231086712 -0.180701334 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005654///nucleoplasm+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0035861///site of double-strand break GO:0003674///molecular_function GO:0006303///double-strand break repair via nonhomologous end joining+++GO:1990166///protein localization to site of double-strand break+++GO:1990683///DNA double-strand break attachment to nuclear envelope 320679 320679 'Samd12' mRNA 400 432 418 6.62 7.12 6.36 2.52 2.91 2.62 6.7 2.683333333 183.03 169 173 416.6666667 175.01 7.91E-18 -1.264399578 GO:0009898///cytoplasmic side of plasma membrane GO:0003674///molecular_function GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway 320683 320683 'Zfp629' mRNA 556 601 600 5.07 5.44 5.83 3.59 4.1 3.68 5.446666667 3.79 454 510 449 585.6666667 471 0.011219292 -0.326496518 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 320685 320685 'Dctd' mRNA 78 63 54 2.22 1.71 1.53 2.58 2.46 1.95 1.82 2.33 109 100 80 65 96.33333333 0.067883951 0.558576924 00240///Pyrimidine metabolism GO:0003824///catalytic activity+++GO:0004132///dCMP deaminase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006220///pyrimidine nucleotide metabolic process+++GO:0006226///dUMP biosynthetic process+++GO:0006231///dTMP biosynthetic process+++GO:0008152///metabolic process+++GO:0009165///nucleotide biosynthetic process 320696 320696 'Ccdc158' mRNA 42 39 37 0.68 0.6 0.6 0.21 0.16 0.16 0.626666667 0.176666667 15 11 11 39.33333333 12.33333333 8.52E-04 -1.686010696 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320700 320700 'A930033H14Rik' mRNA 1169 1178 1040 21.64 21.46 20.43 2.35 2.16 2.28 21.17666667 2.263333333 146 131 137 1129 138 2.97E-147 -3.042617897 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 320701 320701 'Tafa4' mRNA 669.52 602.82 600.18 15.96 14.14 15.17 8.06 7.14 7.89 15.09 7.696666667 389.15 336.6 368.63 624.1733333 364.7933333 4.42E-11 -0.788013275 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0048018///receptor ligand activity GO:0006909///phagocytosis+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0042391///regulation of membrane potential+++GO:0042554///superoxide anion generation+++GO:0048246///macrophage chemotaxis+++GO:0051930///regulation of sensory perception of pain 320705 320705 'Bend6' mRNA 64 60 24 1.65 1.53 0.62 0.53 0.59 0.54 1.266666667 0.553333333 24 27 21 49.33333333 24 0.032911053 -1.033953134 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity "GO:0007399///nervous system development+++GO:0045666///positive regulation of neuron differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated" 320706 320706 'Soga1' mRNA 679 688 639 2.67 2.68 2.67 1.58 1.63 1.76 2.673333333 1.656666667 461 466 500 668.6666667 475.6666667 5.86E-06 -0.501955412 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0008286///insulin receptor signaling pathway+++GO:0010506///regulation of autophagy+++GO:0045721///negative regulation of gluconeogenesis 320707 320707 'Atp2b3' mRNA 139 125 132 1.48 1.06 1.17 0.14 0.16 0.12 1.236666667 0.14 17 22 14 132 17.66666667 5.85E-19 -2.913455413 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04925///Aldosterone synthesis and secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04972///Pancreatic secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:1990032///parallel fiber GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0019829///cation-transporting ATPase activity+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding+++GO:1905056///calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0070588///calcium ion transmembrane transport+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1990034///calcium ion export across plasma membrane 320709 320709 'Tmem117' mRNA 3416 3553 3402 67.85 69.46 71.68 11.39 11.63 12.96 69.66333333 11.99333333 660 658 727 3457 681.6666667 2.86E-213 -2.354137114 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 320712 320712 'Abi3bp' mRNA 102 102 85 1.22 1.15 1.02 0.53 0.37 0.17 1.13 0.356666667 50 32 16 96.33333333 32.66666667 2.27E-05 -1.57380277 GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005518///collagen binding+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding GO:0008285///negative regulation of cell proliferation+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:1904597///negative regulation of connective tissue replacement involved in inflammatory response wound healing+++GO:1905209///positive regulation of cardiocyte differentiation 320713 320713 'Mysm1' mRNA 1255.12 1324.99 1307.9 10.02 10.19 10.73 6.97 6.94 7.08 10.31333333 6.996666667 1019.11 984.25 997.91 1296.003333 1000.423333 8.95E-06 -0.386166595 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity GO:0002376///immune system process+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006508///proteolysis+++GO:0030334///regulation of cell migration+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0043473///pigmentation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051797///regulation of hair follicle development+++GO:1903706///regulation of hemopoiesis 320714 320714 'Trappc11' mRNA 1109 1038 1137 13.8 12.7 15.01 10.55 8.95 10.15 13.83666667 9.883333333 976 809 910 1094.666667 898.3333333 0.004463922 -0.300735888 GO:0005794///Golgi apparatus+++GO:0030008///TRAPP complex GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0016192///vesicle-mediated transport+++GO:0045054///constitutive secretory pathway+++GO:0061635///regulation of protein complex stability 320717 320717 'Pptc7' mRNA 608.35 668.27 601.49 7.07 7.64 7.42 5.61 5.38 5.58 7.376666667 5.523333333 554.96 520.27 535.48 626.0366667 536.9033333 0.043651178 -0.233520401 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0010795///regulation of ubiquinone biosynthetic process+++GO:0070262///peptidyl-serine dephosphorylation 320718 320718 'Slc26a9' mRNA 0 1 0 0 0.01 0 0.3 0.15 0.11 0.003333333 0.186666667 24 13 11 0.333333333 16 2.89E-04 5.462170386 04978///Mineral absorption+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005254///chloride channel activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity+++GO:0051117///ATPase binding GO:0006811///ion transport+++GO:0006820///anion transport+++GO:0006821///chloride transport+++GO:0006885///regulation of pH+++GO:0008272///sulfate transport+++GO:0010628///positive regulation of gene expression+++GO:0015701///bicarbonate transport+++GO:0019532///oxalate transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport 320720 320720 'Fastkd1' mRNA 60 67 67 1.17 1.34 1.46 1.4 1.76 1.3 1.323333333 1.486666667 78 95 72 64.66666667 81.66666667 0.339887318 0.325085928 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0003723///RNA binding GO:0000959///mitochondrial RNA metabolic process+++GO:0000963///mitochondrial RNA processing+++GO:0044528///regulation of mitochondrial mRNA stability 320722 320722 'Akain1' mRNA 0 2 4 0 0.05 0.1 0 0 0 0.05 0 0 0 0 2 0 0.282926929 -3.488173787 GO:0005829///cytosol GO:0051018///protein kinase A binding GO:0008104///protein localization+++GO:0031333///negative regulation of protein complex assembly 320727 320727 'Ipo8' mRNA 805 832 649 8.02 8.16 6.86 7.54 7.1 6.96 7.68 7.2 872 802 778 762 817.3333333 0.461687861 0.092977456 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0031267///small GTPase binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006606///protein import into nucleus+++GO:0006691///leukotriene metabolic process+++GO:0006810///transport+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0071716///leukotriene transport 320736 320736 'Vstm4' mRNA 1575 1611 1444 31.72 31.94 30.9 15.16 13.99 13.32 31.52 14.15666667 865 779 735 1543.333333 793 1.65E-30 -0.971842976 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0001935///endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0008150///biological_process+++GO:0042311///vasodilation+++GO:0043542///endothelial cell migration+++GO:0061298///retina vasculature development in camera-type eye+++GO:0097601///retina blood vessel maintenance 320747 320747 'Lingo4' mRNA 25 25 30 0.4 0.39 0.59 0.52 0.36 0.61 0.46 0.496666667 33 26 38 26.66666667 32.33333333 0.657569147 0.260995187 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0051965///positive regulation of synapse assembly 320769 320769 'Prdx6b' mRNA 1 1 0 0.02 0.02 0 0.02 0.02 0 0.013333333 0.013333333 1 1 0 0.666666667 0.666666667 0.998591786 0.015061588 00480///Glutathione metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004623///phospholipase A2 activity+++GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0051920///peroxiredoxin activity "GO:0006979///response to oxidative stress+++GO:0042744///hydrogen peroxide catabolic process+++GO:0045454///cell redox homeostasis+++GO:0046475///glycerophospholipid catabolic process+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0098869///cellular oxidant detoxification" 320772 320772 'Mdga2' mRNA 15 26 29 0.08 0.2 0.31 0.07 0.18 0.21 0.196666667 0.153333333 12 16 15.08 23.33333333 14.36 0.277070081 -0.719706129 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0003674///molecular_function GO:0001764///neuron migration+++GO:0007389///pattern specification process+++GO:0099179///regulation of synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 320782 320782 'Tmem154' mRNA 76 80 72 1.24 1.28 1.25 5.96 5.68 6.53 1.256666667 6.056666667 420 391 446 76 419 5.30E-46 2.452067443 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320790 320790 'Chd7' mRNA 2136 2250 1857 10.53 10.91 9.7 5.35 4.7 5.23 10.38 5.093333333 1250 1078 1187 2081 1171.666667 2.15E-26 -0.838321687 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity+++GO:1990841///promoter-specific chromatin binding GO:0001501///skeletal system development+++GO:0001568///blood vessel development+++GO:0001701///in utero embryonic development+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003226///right ventricular compact myocardium morphogenesis+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing+++GO:0007417///central nervous system development+++GO:0007512///adult heart development+++GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0007628///adult walking behavior+++GO:0008015///blood circulation+++GO:0009617///response to bacterium+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0021545///cranial nerve development+++GO:0021553///olfactory nerve development+++GO:0021772///olfactory bulb development+++GO:0030217///T cell differentiation+++GO:0030540///female genitalia development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0035904///aorta development+++GO:0035909///aorta morphogenesis+++GO:0036302///atrioventricular canal development+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042048///olfactory behavior+++GO:0042471///ear morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0043010///camera-type eye development+++GO:0043584///nose development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048752///semicircular canal morphogenesis+++GO:0048771///tissue remodeling+++GO:0048806///genitalia development+++GO:0048844///artery morphogenesis+++GO:0050767///regulation of neurogenesis+++GO:0050890///cognition+++GO:0060021///roof of mouth development+++GO:0060041///retina development in camera-type eye+++GO:0060123///regulation of growth hormone secretion+++GO:0060173///limb development+++GO:0060324///face development+++GO:0060384///innervation+++GO:0060411///cardiac septum morphogenesis+++GO:0060429///epithelium development+++GO:0062009///secondary palate development 320795 320795 'Pkn1' mRNA 685.47 720.44 607.33 5.72 6.24 5.32 8.27 8.31 9.3 5.76 8.626666667 1188.44 1142.6 1271.66 671.08 1200.9 2.31E-19 0.830521314 04151///PI3K-Akt signaling pathway+++04621///NOD-like receptor signaling pathway+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031267///small GTPase binding+++GO:0035402///histone kinase activity (H3-T11 specific)+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding "GO:0001782///B cell homeostasis+++GO:0001783///B cell apoptotic process+++GO:0001841///neural tube formation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002634///regulation of germinal center formation+++GO:0002637///regulation of immunoglobulin production+++GO:0003014///renal system process+++GO:0003157///endocardium development+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0006972///hyperosmotic response+++GO:0007165///signal transduction+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010631///epithelial cell migration+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030889///negative regulation of B cell proliferation+++GO:0032092///positive regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0035329///hippo signaling+++GO:0035407///histone H3-T11 phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046330///positive regulation of JNK cascade+++GO:0046621///negative regulation of organ growth+++GO:0048536///spleen development+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051262///protein tetramerization+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060215///primitive hemopoiesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000145///regulation of cell motility" 320799 320799 'Zhx3' mRNA 613 572 479 7.35 6.74 6.09 2.65 2.4 2.88 6.726666667 2.643333333 255 225 268 554.6666667 249.3333333 7.86E-18 -1.162185143 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005938///cell cortex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 320802 320802 'Ifitm10' mRNA 277 212 217 12.44 9.33 10.45 17.23 16.3 15.69 10.74 16.40666667 441 411 388 235.3333333 413.3333333 1.66E-07 0.801247561 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320806 320806 'Gfm2' mRNA 509.84 536.67 597.5 7.33 7.78 9.41 9.06 7.08 7.81 8.173333333 7.983333333 756.45 555.81 650.14 548.0033333 654.1333333 0.105697078 0.237997211 GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0032790///ribosome disassembly 320808 320808 'Dcaf5' mRNA 652 673 668 6.07 6.16 6.64 5.25 5.2 4.45 6.29 4.966666667 639 619 530 664.3333333 596 0.185539349 -0.169659612 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 320816 320816 'Ankrd16' mRNA 456 490 440 13.47 13.81 15.32 11.88 10.99 11.71 14.2 11.52666667 481 432 465 462 459.3333333 0.899676168 -0.019702427 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006400///tRNA modification 320817 320817 'Atad2b' mRNA 312.07 284.49 272.9 2.04 1.71 1.93 1.74 1.35 1.46 1.893333333 1.516666667 285.51 241.42 245.07 289.82 257.3333333 0.306640046 -0.183064605 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042393///histone binding+++GO:0070577///lysine-acetylated histone binding GO:0031936///negative regulation of chromatin silencing+++GO:0045944///positive regulation of transcription by RNA polymerase II 320825 320825 'Samd5' mRNA 52 37 39 1.12 0.8 0.91 1.48 1.62 1.41 0.943333333 1.503333333 77 84 71 42.66666667 77.33333333 0.01196107 0.847953951 GO:0005737///cytoplasm 320827 320827 'Cracd' mRNA 522 582 484 3.6 3.99 3.52 0.93 0.75 0.79 3.703333333 0.823333333 151 125 132 529.3333333 136 1.39E-41 -1.970984617 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0010669///epithelial structure maintenance+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030838///positive regulation of actin filament polymerization+++GO:2000813///negative regulation of barbed-end actin filament capping 320832 320832 'Sirpb1a' mRNA 12.83 5 1.09 0.64 0.24 0.06 3.9 3.8 4.78 0.313333333 4.16 90.19 85.67 106.9 6.306666667 94.25333333 1.71E-15 3.962810329 04380///Osteoclast differentiation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0035556///intracellular signal transduction+++GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation 320840 320840 'Negr1' mRNA 656.47 607.97 562.36 6.38 5.74 6 1.15 0.75 1.08 6.04 0.993333333 142.63 121.78 114.29 608.9333333 126.2333333 5.24E-57 -2.286533337 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031225///anchored component of membrane+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007626///locomotory behavior+++GO:0007631///feeding behavior+++GO:0010976///positive regulation of neuron projection development+++GO:0051963///regulation of synapse assembly+++GO:0098609///cell-cell adhesion 320844 320844 'Amigo3' mRNA 153 111.31 150.09 3.35 2.4 3.48 2.5 1.72 1.66 3.076666667 1.96 131.23 88.38 84.41 138.1333333 101.34 0.095789288 -0.470468099 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0044877///protein-containing complex binding GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0010977///negative regulation of neuron projection development+++GO:0051965///positive regulation of synapse assembly 320858 320858 'L3mbtl4' mRNA 8 4 3 0.11 0.07 0.04 0 0.02 0 0.073333333 0.006666667 0 3 0 5 1 0.211950397 -2.308490384 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated" 320864 320864 'Krt26' mRNA 0 1 2 0 0.02 0.05 0 0 0 0.023333333 0 0 0 0 1 0 0.596502362 -2.487866303 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 320865 320865 'Cdh18' mRNA 496 469 467 5.6 5.56 5.25 0.59 0.6 0.87 5.47 0.686666667 52 57 74 477.3333333 61 4.78E-61 -2.979387191 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 320869 320869 'Spata33' mRNA 563 496 594 19.51 15.48 21.72 4.02 5.94 3.97 18.90333333 4.643333333 163 181 126 551 156.6666667 1.14E-28 -1.829852784 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 320873 320873 'Cdh10' mRNA 36 27 28 0.52 0.43 0.5 0.2 0.31 0.15 0.483333333 0.22 15 22 10 30.33333333 15.66666667 0.095183798 -0.961742226 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding GO:0000902///cell morphogenesis+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 320878 320878 'Mical2' mRNA 91 120 96 1.04 1.23 1.04 1.26 1.22 1.24 1.103333333 1.24 160 148 153 102.3333333 153.6666667 0.012737893 0.576307698 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0031941///filamentous actin "GO:0003779///actin binding+++GO:0004497///monooxygenase activity+++GO:0005515///protein binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0043914///NADPH:sulfur oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0071949///FAD binding" GO:0001947///heart looping+++GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007507///heart development+++GO:0008150///biological_process+++GO:0010735///positive regulation of transcription via serum response element binding+++GO:0019417///sulfur oxidation+++GO:0030036///actin cytoskeleton organization+++GO:0030042///actin filament depolymerization+++GO:0030154///cell differentiation 320910 320910 'Itgb8' mRNA 1543 1548 1358 11.2 11.6 10.86 12.05 10.83 11.3 11.22 11.39333333 1800 1572 1641 1483 1671 0.052031359 0.161468678 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04514///Cell adhesion molecules+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0008305///integrin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034686///integrin alphav-beta8 complex GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0038023///signaling receptor activity+++GO:1990430///extracellular matrix protein binding GO:0001570///vasculogenesis+++GO:0001573///ganglioside metabolic process+++GO:0006955///immune response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016477///cell migration+++GO:0033627///cell adhesion mediated by integrin+++GO:0045766///positive regulation of angiogenesis+++GO:0051216///cartilage development+++GO:0060022///hard palate development+++GO:0061520///Langerhans cell differentiation+++GO:1901388///regulation of transforming growth factor beta activation 320916 320916 'Wscd2' mRNA 667 767 682 8.34 9.43 9.03 2.17 1.66 1.82 8.933333333 1.883333333 201 149 162 705.3333333 170.6666667 5.92E-51 -2.06011661 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 320923 320923 'Map7d3' mRNA 18 12 19 0.34 0.22 0.36 0.19 0.38 0.19 0.306666667 0.253333333 11 22 12 16.33333333 15 0.867122445 -0.13615331 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0008017///microtubule binding+++GO:0015631///tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0046785///microtubule polymerization 320924 320924 'Ccbe1' mRNA 112 92 74 1.04 0.84 0.73 0.75 0.62 0.7 0.87 0.69 93 75 84 92.66666667 84 0.67373063 -0.149838115 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0002020///protease binding+++GO:0005509///calcium ion binding+++GO:0005518///collagen binding GO:0001525///angiogenesis+++GO:0001945///lymph vessel development+++GO:0001946///lymphangiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0003016///respiratory system process+++GO:0007275///multicellular organism development+++GO:0007585///respiratory gaseous exchange+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010954///positive regulation of protein processing+++GO:0030324///lung development+++GO:0045766///positive regulation of angiogenesis+++GO:0048845///venous blood vessel morphogenesis+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway+++GO:1901492///positive regulation of lymphangiogenesis 320938 320938 'Tnpo3' mRNA 1562.52 1528.25 1643.35 20.16 19.15 22.53 18.25 16.05 17.34 20.61333333 17.21333333 1625.19 1418.91 1515.75 1578.04 1519.95 0.521164617 -0.069567817 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005642///annulate lamellae+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0006606///protein import into nucleus+++GO:0015031///protein transport 320940 320940 'Atp11c' mRNA 200 214 211 1.76 1.83 1.93 2.43 1.94 2.39 1.84 2.253333333 319 247 304 208.3333333 290 0.007859126 0.462871242 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity GO:0002329///pre-B cell differentiation+++GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0045332///phospholipid translocation+++GO:0045579///positive regulation of B cell differentiation 320951 320951 'Pisd' mRNA 2758 2752 2698 66.12 64.75 68.64 73.27 71.7 72.07 66.50333333 72.34666667 3546 3394 3350 2736 3430 6.61E-07 0.313728326 00564///Glycerophospholipid metabolism GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0004609///phosphatidylserine decarboxylase activity+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010821///regulation of mitochondrion organization+++GO:0016540///protein autoprocessing+++GO:0035694///mitochondrial protein catabolic process 320974 320974 'Lrrn4' mRNA 0 3 0 0 0.05 0 0.09 0.09 0.06 0.016666667 0.08 3 4 2 1 3 0.486491823 1.607062689 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007616///long-term memory+++GO:0008542///visual learning 320981 320981 'Enpp6' mRNA 274 298 251 2.95 3.15 2.86 11.45 11.2 11.18 2.986666667 11.27666667 1227 1172 1160 274.3333333 1186.333333 2.68E-94 2.102462049 00565///Ether lipid metabolism GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0003824///catalytic activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008889///glycerophosphodiester phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047390///glycerophosphocholine cholinephosphodiesterase activity GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0019695///choline metabolic process 320982 320982 'Arl4c' mRNA 1188 1265 800 16.17 16.94 11.55 14.59 13.5 14.09 14.88666667 14.06 1234 1115 1154 1084.333333 1167.666667 0.48522102 0.103289034 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030175///filopodium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0043014///alpha-tubulin binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling 320997 320997 'Cyp4f39' mRNA 459 508 444 9.79 11 10.25 0.62 0.71 0.6 10.34666667 0.643333333 33 37 31 470.3333333 33.66666667 9.49E-79 -3.814389049 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0046513///ceramide biosynthetic process 321000 321000 'Lrif1' mRNA 404 406 399 8 8.5 8.68 7.26 5.51 6.77 8.393333333 6.513333333 380 311 341 403 344 0.101066237 -0.241925022 "GO:0000781///chromosome, telomeric region+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016363///nuclear matrix+++GO:0034451///centriolar satellite" GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0009048///dosage compensation by inactivation of X chromosome" 321003 321003 'Xpnpep3' mRNA 490 512 443 4.24 4.34 4.06 3.11 2.92 2.64 4.213333333 2.89 413 379 339 481.6666667 377 0.00621601 -0.364030305 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0003094///glomerular filtration+++GO:0006508///proteolysis+++GO:0016485///protein processing 321006 321006 'Dcaf1' mRNA 636 625 653 5.94 5.74 6.47 4.77 3.81 3.94 6.05 4.173333333 589 459 472 638 506.6666667 0.007010336 -0.348116827 05170///Human immunodeficiency virus 1 infection GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030331///estrogen receptor binding+++GO:1990244///histone kinase activity (H2A-T120 specific) GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0030183///B cell differentiation+++GO:0033151///V(D)J recombination+++GO:0035212///cell competition in a multicellular organism+++GO:1990245///histone H2A-T120 phosphorylation 321007 321007 'Serac1' mRNA 296.27 292.59 267.96 2.88 2.81 2.74 2.69 2.71 2.61 2.81 2.67 322.28 312.8 303.52 285.6066667 312.8666667 0.489874651 0.121475029 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0044233///Mitochondria-associated ER Membrane GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0030198///extracellular matrix organization+++GO:0032367///intracellular cholesterol transport+++GO:0036148///phosphatidylglycerol acyl-chain remodeling 321008 321008 'Zswim9' mRNA 241.07 241.02 207.54 3.93 3.86 3.59 2.49 2.24 2.87 3.793333333 2.533333333 175.85 154.26 196 229.8766667 175.37 0.035180314 -0.401887181 GO:0008270///zinc ion binding GO:0002244///hematopoietic progenitor cell differentiation 321019 321019 'Gpr183' mRNA 83 74 96 1.59 1.39 1.9 7.86 8.1 7.49 1.626666667 7.816666667 477 480 439 84.33333333 465.3333333 3.92E-46 2.449081631 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008142///oxysterol binding GO:0002250///adaptive immune response+++GO:0002312///B cell activation involved in immune response+++GO:0002313///mature B cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0002407///dendritic cell chemotaxis+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010818///T cell chemotaxis+++GO:0030316///osteoclast differentiation+++GO:0030595///leukocyte chemotaxis+++GO:0030890///positive regulation of B cell proliferation+++GO:0036145///dendritic cell homeostasis+++GO:0060326///cell chemotaxis+++GO:0061470///T follicular helper cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000458///regulation of astrocyte chemotaxis 321022 321022 'Cdv3' mRNA 748.01 807 600 11.95 12.74 10.16 13.85 10.82 13.44 11.61666667 12.70333333 994 757 931.2 718.3366667 894.0666667 0.013771995 0.306983482 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 326618 326618 'Tpm4' mRNA 1690 1683 1589 45.61 44.74 45.49 156 162.96 157.65 45.28 158.87 6647 6779 6502 1654 6642.666667 6.51E-252 1.994961681 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0001725///stress fiber+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0030863///cortical cytoskeleton GO:0003779///actin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization 326619 326619 'H4c1' mRNA 0 2.6 0 0 0.52 0 0.52 0.46 2.12 0.173333333 1.033333333 2.96 2.53 11.61 0.866666667 5.7 0.145783098 2.92321684 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 326620 326620 'H4c2' mRNA 2.11 0 1.59 0.43 0 0.34 0 0 0 0.256666667 0 0 0 0 1.233333333 0 0.60428608 -2.461629596 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 326622 326622 'Upf2' mRNA 823 783.22 791 8.34 7.82 8.52 4.69 4.78 5.04 8.226666667 4.836666667 535 531 556 799.0733333 540.6666667 3.30E-08 -0.575617675 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0035145///exon-exon junction complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0042162///telomeric DNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001889///liver development+++GO:0006986///response to unfolded protein+++GO:0031100///animal organ regeneration" 326623 326623 'Tnfsf15' mRNA 70 80 92 0.64 0.72 0.9 0.93 0.92 1.1 0.753333333 0.983333333 117 112 134 80.66666667 121 0.035970132 0.569009563 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005123///death receptor binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding GO:0001816///cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007250///activation of NF-kappaB-inducing kinase activity 327655 327655 'Ppip5k1' mRNA 1170 1219 944 10.59 10.73 9.04 6.05 6.01 5.53 10.12 5.863333333 776 731 684 1111 730.3333333 8.67E-10 -0.61294453 04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033857///diphosphoinositol-pentakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0102092///5-diphosphoinositol pentakisphosphate 3-kinase activity" GO:0006020///inositol metabolic process+++GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process 327743 327743 'Ccn6' mRNA 9.36 12.89 13.32 0.06 0.08 0.1 0.09 0.08 0.13 0.08 0.1 14.07 13.4 23 11.85666667 16.82333333 0.501612892 0.541431431 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0031012///extracellular matrix GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding+++GO:0008083///growth factor activity+++GO:0008201///heparin binding GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0016525///negative regulation of angiogenesis+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060548///negative regulation of cell death+++GO:1903426///regulation of reactive oxygen species biosynthetic process 327747 327747 'Mettl24' mRNA 178 226 192 6.6 8.14 7.41 1.68 1.39 2.47 7.383333333 1.846666667 53 43 72 198.6666667 56 8.77E-14 -1.837909543 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0008150///biological_process+++GO:0032259///methylation 327762 327762 'Dna2' mRNA 75.57 54.01 41 0.9 0.63 0.51 2.19 1.92 2.34 0.68 2.15 203.14 174.09 218.04 56.86 198.4233333 3.50E-13 1.800762884 03030///DNA replication "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005760///gamma DNA polymerase complex+++GO:0042645///mitochondrial nucleoid" "GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004386///helicase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016890///site-specific endodeoxyribonuclease activity, specific for altered base+++GO:0017108///5'-flap endonuclease activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0043139///5'-3' DNA helicase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0000076///DNA replication checkpoint+++GO:0000723///telomere maintenance+++GO:0000729///DNA double-strand break processing+++GO:0006260///DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0032508///DNA duplex unwinding+++GO:0033567///DNA replication, Okazaki fragment processing+++GO:0043137///DNA replication, removal of RNA primer+++GO:0043504///mitochondrial DNA repair+++GO:0045740///positive regulation of DNA replication+++GO:0071932///replication fork reversal+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1902990///mitotic telomere maintenance via semi-conservative replication" 327766 327766 'Tmem26' mRNA 187 212 182 1.98 2.2 2.04 1.15 1.03 1.25 2.073333333 1.143333333 125 110 132 193.6666667 122.3333333 9.14E-04 -0.673443869 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 327799 327799 'Usp44' mRNA 13 3.88 7.7 0.14 0.04 0.09 0.08 0.11 0.09 0.09 0.093333333 8.42 11.13 8.86 8.193333333 9.47 0.863090843 0.220573033 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0016579///protein deubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051301///cell division+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1904667///negative regulation of ubiquitin protein ligase activity 327814 327814 'Ppfia2' mRNA 65.61 65.33 60.3 0.31 0.42 0.42 0.24 0.13 0.15 0.383333333 0.173333333 59.59 35.67 43.92 63.74666667 46.39333333 0.202724858 -0.486483175 GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0098978///glutamatergic synapse+++GO:0099523///presynaptic cytosol GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0099181///structural constituent of presynapse GO:0050808///synapse organization+++GO:0060998///regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0099172///presynapse organization+++GO:0099519///dense core granule cytoskeletal transport+++GO:2000300///regulation of synaptic vesicle exocytosis 327826 327826 'Frs2' mRNA 992.72 1111.78 974.78 8.28 9.16 8.59 7.38 7.01 7.26 8.676666667 7.216666667 1017.03 938.9 961.6 1026.426667 972.51 0.406658399 -0.088558693 04714///Thermogenesis+++04722///Neurotrophin signaling pathway+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005104///fibroblast growth factor receptor binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005515///protein binding "GO:0000187///activation of MAPK activity+++GO:0001702///gastrulation with mouth forming second+++GO:0001759///organ induction+++GO:0002088///lens development in camera-type eye+++GO:0003281///ventricular septum development+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007405///neuroblast proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0030900///forebrain development+++GO:0042981///regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0046619///optic placode formation involved in camera-type eye formation+++GO:0050678///regulation of epithelial cell proliferation+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0070307///lens fiber cell development+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000726///negative regulation of cardiac muscle cell differentiation" 327900 327900 'Ubtd2' mRNA 766 865 696 13.96 15.44 13.49 6.59 7.32 7.75 14.29666667 7.22 419 455 476 775.6666667 450 3.50E-12 -0.793211726 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 327942 327942 'Pigl' mRNA 496.8 427.24 483.89 11.13 10.18 11.38 10.58 10.06 12.9 10.89666667 11.18 535.11 484.01 583.96 469.31 534.36 0.243117941 0.173988501 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000225///N-acetylglucosaminylphosphatidylinositol deacetylase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides" GO:0006506///GPI anchor biosynthetic process 327951 327951 'Cyb5d1' mRNA 1273.08 1403.55 1299.94 19.15 20.69 20.55 14.38 12.39 13.17 20.13 13.31333333 1115.71 953.99 991.04 1325.523333 1020.246667 1.36E-05 -0.39074792 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 327954 327954 'Dnah2' mRNA 507 511 444 1.84 1.82 1.72 0.3 0.23 0.22 1.793333333 0.25 83 71 68 487.3333333 74 1.17E-60 -2.729687871 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0007018///microtubule-based movement+++GO:0060285///cilium-dependent cell motility 327956 327956 'Vmo1' mRNA 1967 1976 2049 212.65 212.28 235.11 18.55 24.81 19.72 220.0133333 21.02666667 196 255 201 1997.333333 217.3333333 5.14E-181 -3.212319917 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0008150///biological_process 327957 327957 'Scimp' mRNA 33 26 37 1.97 1.54 2.35 10.75 10.28 11.28 1.953333333 10.77 206 192 209 32 202.3333333 6.42E-25 2.645240358 GO:0001726///ruffle+++GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030175///filopodium+++GO:0031256///leading edge membrane+++GO:0031259///uropod membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045335///phagocytic vesicle+++GO:0097197///tetraspanin-enriched microdomain GO:0005515///protein binding+++GO:0060090///molecular adaptor activity GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002732///positive regulation of dendritic cell cytokine production+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0038123///toll-like receptor TLR1:TLR2 signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071226///cellular response to molecule of fungal origin 327958 327958 'Pitpnm3' mRNA 341 277 309 2.72 2.18 2.63 0.73 0.63 0.59 2.51 0.65 105 90 82 309 92.33333333 2.60E-20 -1.757119293 GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0042995///cell projection+++GO:0044297///cell body GO:0004620///phospholipase activity+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding 327959 327959 'Xaf1' mRNA 1080.63 1128.79 1094.49 25.86 29.72 29.35 41.79 44.3 44.91 28.31 43.66666667 1938.71 1990.1 1936.23 1101.303333 1955.013333 2.42E-26 0.816820061 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0031333///negative regulation of protein complex assembly+++GO:0035456///response to interferon-beta 327978 327978 'Slfn5' mRNA 254.83 196.58 219.83 2.2 1.68 2 10.25 9.17 10.94 1.96 10.12 1355.23 1190.4 1403.96 223.7466667 1316.53 3.06E-103 2.548139935 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0005524///ATP binding GO:0030154///cell differentiation 327987 327987 'Med13' mRNA 1247 1113 1113 6.19 5.43 5.86 5.88 4.5 5.45 5.826666667 5.276666667 1365 1021 1225 1157.666667 1203.666667 0.76697852 0.042257849 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0046966///thyroid hormone receptor binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042632///cholesterol homeostasis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0070328///triglyceride homeostasis" 327992 327992 'Hsf5' mRNA 18 21 12 0.23 0.27 0.16 0.1 0.08 0.07 0.22 0.083333333 9 7 6 17 7.333333333 0.11547564 -1.217474838 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 328035 328035 'Fads6' mRNA 447 425 397 3.96 3.7 3.73 2.58 2.2 2.69 3.796666667 2.49 336 280 339 423 318.3333333 0.002816086 -0.421758614 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process 328092 328092 'Dtd2' mRNA 644 657 651 17.18 17.03 17.5 20.07 18.89 18.11 17.23666667 19.02333333 818 752 704 650.6666667 758 0.067485481 0.207095357 GO:0005737///cytoplasm GO:0000049///tRNA binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0051499///D-aminoacyl-tRNA deacylase activity+++GO:0051500///D-tyrosyl-tRNA(Tyr) deacylase activity+++GO:0106105///Ala-tRNA(Thr) hydrolase activity GO:0006399///tRNA metabolic process+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 328099 328099 'Prps1l3' mRNA 923.87 1007.18 911.85 12.45 13.35 13.03 12.02 11.31 10.81 12.94333333 11.38 1026.95 943.53 894.56 947.6333333 955.0133333 0.998591786 -6.00E-04 00030///Pentose phosphate pathway+++00230///Purine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006144///purine nucleobase metabolic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0007399///nervous system development+++GO:0009116///nucleoside metabolic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0034418///urate biosynthetic process+++GO:0044249///cellular biosynthetic process+++GO:0046101///hypoxanthine biosynthetic process 328108 328108 'Togaram1' mRNA 1317 1342 1433 11.39 11.27 13.47 8.58 8.58 8.57 12.04333333 8.576666667 1138 1125 1108 1364 1123.666667 0.001710231 -0.293942788 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0072686///mitotic spindle GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0030030///cell projection organization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0035082///axoneme assembly+++GO:0090307///mitotic spindle assembly+++GO:1905515///non-motile cilium assembly 328110 328110 'Prpf39' mRNA 1197.21 1165.11 1113.22 14.67 14.32 14.88 10.7 10.47 11.16 14.62333333 10.77666667 992.86 939.32 1000.82 1158.513333 977.6666667 0.003537181 -0.257113668 GO:0000243///commitment complex+++GO:0005634///nucleus+++GO:0005685///U1 snRNP+++GO:0071004///U2-type prespliceosome GO:0000395///mRNA 5'-splice site recognition+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 328133 328133 'Slc39a9' mRNA 1017 1020 1015 10.33 10.21 10.97 10.72 10.79 10.03 10.50333333 10.51333333 1211 1191 1093.01 1017.333333 1165.003333 0.056367701 0.182955532 05010///Alzheimer disease+++05012///Parkinson disease GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0008150///biological_process+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport 328162 328162 'Trmt61a' mRNA 178 159 130 4.85 4.21 3.73 6.02 5.76 5.11 4.263333333 5.63 267 250 212 155.6666667 243 9.68E-04 0.633994026 GO:0005634///nucleus+++GO:0031515///tRNA (m1A) methyltransferase complex GO:0008168///methyltransferase activity+++GO:0016429///tRNA (adenine-N1-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0061953///mRNA (adenine-N1-)-methyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0080009///mRNA methylation 328232 328232 'Gfod1' mRNA 34 30 49 0.27 0.24 0.42 0.55 0.48 0.68 0.31 0.57 78 68 95 37.66666667 80.33333333 0.002826426 1.071429632 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0000166///nucleotide binding+++GO:0016491///oxidoreductase activity 328234 328234 'Rnf182' mRNA 244 260 253 3.83 3.92 4.12 1.15 1.37 1.3 3.956666667 1.273333333 84 99 93 252.3333333 92 3.73E-14 -1.466890228 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination 328258 328258 'Slc25a48' mRNA 11 11 9 0.43 0.33 0.34 1.71 1.31 1.59 0.366666667 1.536666667 54 38 50 10.33333333 47.33333333 1.03E-05 2.18391871 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015227///acyl carnitine transmembrane transporter activity GO:0006844///acyl carnitine transport+++GO:0006865///amino acid transport+++GO:1902616///acyl carnitine transmembrane transport 328274 328274 'Zfp459' mRNA 95.57 80.94 82.3 1.17 0.77 0.86 0.93 0.96 0.92 0.933333333 0.936666667 88.96 101.26 87.37 86.27 92.53 0.800369356 0.092469718 05168///Herpes simplex virus 1 infection GO:0005730///nucleolus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 328329 328329 'Mast4' mRNA 1586 1727 1507 8.12 8.68 8.17 7.1 7.32 7.13 8.323333333 7.183333333 1580 1599 1546 1606.666667 1575 0.707083372 -0.038666144 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 328330 328330 'D130037M23Rik' mRNA 336.48 290.77 316.25 1.07 0.91 1.07 0.93 0.76 0.91 1.016666667 0.866666667 336.69 267.65 320.72 314.5 308.3533333 0.847448937 -0.044018218 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 328365 328365 'Zmiz1' mRNA 3279 3171 1910 22.87 21.75 14.17 14.3 16.28 16.31 19.59666667 15.63 2349 2624 2599 2786.666667 2524 0.63082596 -0.141602269 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding "GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0003007///heart morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007296///vitellogenesis+++GO:0007569///cell aging+++GO:0021852///pyramidal neuron migration+++GO:0030521///androgen receptor signaling pathway+++GO:0033233///regulation of protein sumoylation+++GO:0045582///positive regulation of T cell differentiation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048589///developmental growth+++GO:0048844///artery morphogenesis+++GO:0060395///SMAD protein signal transduction+++GO:1903508///positive regulation of nucleic acid-templated transcription" 328370 328370 'Rft1' mRNA 677.02 619 615.4 15.53 14.17 15.18 12.84 11.2 11.69 14.96 11.91 639.86 543.07 560.77 637.14 581.2333333 0.251398709 -0.146483573 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0008643///carbohydrate transport+++GO:0034203///glycolipid translocation 328381 328381 'Sh2d4b' mRNA 1343 1349 1290 12.13 11.67 12.77 1.38 1.75 1.85 12.19 1.66 211 186 202 1327.333333 199.6666667 1.74E-148 -2.745082641 GO:0005737///cytoplasm 328417 328417 'Parp4' mRNA 409 418 337 3.39 3.4 2.96 3.3 2.98 3.26 3.25 3.18 458 405 437 388 433.3333333 0.316909822 0.150407721 03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005876///spindle microtubule "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:1990404///protein ADP-ribosylase activity" GO:0006464///cellular protein modification process+++GO:0006471///protein ADP-ribosylation+++GO:0006954///inflammatory response+++GO:0007004///telomere maintenance via telomerase+++GO:0008219///cell death+++GO:0051972///regulation of telomerase activity 328424 328424 'Kcnrg' mRNA 10.94 6.22 6.44 0.34 0.2 0.22 0.26 0.14 0.08 0.253333333 0.16 9.23 5 2.64 7.866666667 5.623333333 0.725084635 -0.474692977 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0097038///perinuclear endoplasmic reticulum GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042802///identical protein binding "GO:0010942///positive regulation of cell death+++GO:0016239///positive regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032897///negative regulation of viral transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization+++GO:0051865///protein autoubiquitination+++GO:1902187///negative regulation of viral release from host cell+++GO:1902260///negative regulation of delayed rectifier potassium channel activity" 328440 328440 'Npm2' mRNA 4 3 2 0.26 0.13 0.14 0.21 0 0.23 0.176666667 0.146666667 5 0 5 3 3.333333333 0.943901747 0.138730878 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding GO:0001824///blastocyst development+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007096///regulation of exit from mitosis+++GO:0007275///multicellular organism development+++GO:0007338///single fertilization+++GO:0009994///oocyte differentiation+++GO:0043085///positive regulation of catalytic activity+++GO:0045740///positive regulation of DNA replication+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051054///positive regulation of DNA metabolic process 328531 328531 '9330182O14Rik' mRNA 2 1 0 0.06 0.03 0 0 0 0 0.03 0 0 0 0 1 0 0.614783931 -2.421998967 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 328561 328561 'Apol10b' mRNA 14 12 17 0.32 0.28 0.46 0.4 0.79 0.39 0.353333333 0.526666667 17 35 15 14.33333333 22.33333333 0.380628492 0.627471846 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 328563 328563 'Apol11b' mRNA 0 1 6 0 0.03 0.18 0.05 0 0.02 0.07 0.023333333 2 0 1 2.333333333 1 0.629650592 -1.300339253 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 328572 328572 'Ep300' mRNA 927.18 891.49 796.45 5.56 5.26 5.06 5.94 4.82 5.44 5.293333333 5.4 1139.84 904.68 1010.8 871.7066667 1018.44 0.047275183 0.212391108 "04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04310///Wnt signaling pathway+++04330///Notch signaling pathway+++04350///TGF-beta signaling pathway+++04520///Adherens junction+++04630///JAK-STAT signaling pathway+++04720///Long-term potentiation+++04916///Melanogenesis+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++04935///Growth hormone synthesis, secretion and action+++05016///Huntington disease+++05152///Tuberculosis+++05161///Hepatitis B+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma+++05215///Prostate cancer" GO:0000123///histone acetyltransferase complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0001216///bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding+++GO:0001221///transcription cofactor binding+++GO:0001223///transcription coactivator binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003823///antigen binding+++GO:0004402///histone acetyltransferase activity+++GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0010484///H3 histone acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016922///nuclear receptor binding+++GO:0031490///chromatin DNA binding+++GO:0033613///activating transcription factor binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051059///NF-kappaB binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0061920///protein propionyltransferase activity+++GO:0097157///pre-mRNA intronic binding+++GO:0097677///STAT family protein binding+++GO:0140065///peptide butyryltransferase activity+++GO:0140068///histone crotonyltransferase activity+++GO:0140069///histone butyryltransferase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001756///somitogenesis+++GO:0001966///thigmotaxis+++GO:0002209///behavioral defense response+++GO:0006110///regulation of glycolytic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006473///protein acetylation+++GO:0006475///internal protein amino acid acetylation+++GO:0006915///apoptotic process+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0007049///cell cycle+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0007611///learning or memory+++GO:0007623///circadian rhythm+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010742///macrophage derived foam cell differentiation+++GO:0010821///regulation of mitochondrion organization+++GO:0010976///positive regulation of neuron projection development+++GO:0016573///histone acetylation+++GO:0018076///N-terminal peptidyl-lysine acetylation+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0018394///peptidyl-lysine acetylation+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0030220///platelet formation+++GO:0030324///lung development+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031333///negative regulation of protein complex assembly+++GO:0031648///protein destabilization+++GO:0032092///positive regulation of protein binding+++GO:0034644///cellular response to UV+++GO:0035264///multicellular organism growth+++GO:0035855///megakaryocyte development+++GO:0036268///swimming+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043627///response to estrogen+++GO:0043923///positive regulation by host of viral transcription+++GO:0043967///histone H4 acetylation+++GO:0043969///histone H2B acetylation+++GO:0045444///fat cell differentiation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051216///cartilage development+++GO:0060325///face morphogenesis+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0061921///peptidyl-lysine propionylation+++GO:0090043///regulation of tubulin deacetylation+++GO:0097043///histone H3-K56 acetylation+++GO:0140066///peptidyl-lysine crotonylation+++GO:0140067///peptidyl-lysine butyrylation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1905636///positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding" 328573 328573 '4930407I10Rik' mRNA 35 36 27 0.4 0.41 0.33 0.08 0.02 0.1 0.38 0.066666667 8 2 10 32.66666667 6.666666667 3.32E-04 -2.303089556 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 328577 328577 '7530416G11Rik' mRNA 1 4 5 0.05 0.21 0.28 0 0 0.05 0.18 0.016666667 0 0 1 3.333333333 0.333333333 0.160342481 -3.244958169 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 328580 328580 'Tubgcp6' mRNA 511.44 573.28 516.79 3.9 4.34 4.25 3.25 3.15 3.09 4.163333333 3.163333333 487.02 457.28 451.68 533.8366667 465.3266667 0.100912113 -0.209316207 GO:0000922///spindle pole+++GO:0000923///equatorial microtubule organizing center+++GO:0000930///gamma-tubulin complex+++GO:0000931///gamma-tubulin large complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0008274///gamma-tubulin ring complex+++GO:0008275///gamma-tubulin small complex GO:0008017///microtubule binding+++GO:0043015///gamma-tubulin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007020///microtubule nucleation+++GO:0031122///cytoplasmic microtubule organization+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle 328643 328643 'Vwa5b2' mRNA 12 4 1 0.15 0.04 0.02 0.02 0.07 0.03 0.07 0.04 2 5 3 5.666666667 3.333333333 0.640692009 -0.74836842 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 328660 328660 'Bex6' mRNA 0 2 0 0 0.13 0 0.28 0.12 0.06 0.043333333 0.153333333 5 2 1 0.666666667 2.666666667 0.42873607 2.005805989 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule GO:0042826///histone deacetylase binding+++GO:0043014///alpha-tubulin binding GO:0007059///chromosome segregation+++GO:0030334///regulation of cell migration+++GO:0042127///regulation of cell proliferation+++GO:1904428///negative regulation of tubulin deacetylation 328778 328778 'Rab26' mRNA 107 112 111 4.44 4.59 4.89 2.24 1.81 1.76 4.64 1.936666667 62 49 47 110 52.66666667 1.20E-04 -1.07700253 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019002///GMP binding "GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0035272///exocrine system development+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045055///regulated exocytosis+++GO:0099575///regulation of protein catabolic process at presynapse, modulating synaptic transmission" 328779 328779 'Hs3st6' mRNA 688 611 570 32.74 29.62 28.91 17.51 16.57 16.54 30.42333333 16.87333333 417 381 367 623 388.3333333 7.63E-09 -0.692689354 GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity GO:0001835///blastocyst hatching 328780 328780 'Prss34' mRNA 0 1 0 0 0.07 0 0 0 0.06 0.023333333 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004252///serine-type endopeptidase activity+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity GO:0006508///proteolysis+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 328783 328783 'Mslnl' mRNA 585 605 572 11.57 11.84 11.8 2.25 1.82 2.36 11.73666667 2.143333333 131 104 129 587.3333333 121.3333333 6.81E-56 -2.287847885 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion 328789 328789 'Lhfpl5' mRNA 2717 2785 2811 124.21 124.94 135.68 14.06 14.26 14.57 128.2766667 14.29666667 356 342 358 2771 352 1.12E-262 -2.99008966 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032421///stereocilium bundle+++GO:0032426///stereocilium tip GO:0005515///protein binding GO:0006811///ion transport+++GO:0007605///sensory perception of sound+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0050974///detection of mechanical stimulus involved in sensory perception+++GO:0060088///auditory receptor cell stereocilium organization 328795 328795 'Ubash3a' mRNA 2 1 8 0.04 0.02 0.16 0.06 0.18 0.12 0.073333333 0.12 4 11 7 3.666666667 7.333333333 0.483097175 0.961830468 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0001817///regulation of cytokine production+++GO:0038065///collagen-activated signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0070527///platelet aggregation 328801 328801 'Zfp414' mRNA 808 804 670 44.36 43.61 39.03 25.99 29.1 27.08 42.33333333 27.39 543 593 547 760.6666667 561 5.17E-05 -0.446989976 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 328829 328829 '9830107B12Rik' mRNA 1 2 0 0.02 0.04 0 0.22 0.12 0.22 0.02 0.186666667 12.97 6.74 13 1 10.90333333 0.013123673 3.369384543 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity 328830 328830 'A530064D06Rik' mRNA 3.97 7.33 6 0.13 0.22 0.22 2.36 1.9 2.3 0.19 2.186666667 87.08 68.58 83.54 5.766666667 79.73333333 1.77E-14 3.881146692 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity 328833 328833 'Treml2' mRNA 4 8 4 0.05 0.1 0.05 1.11 0.84 1.32 0.066666667 1.09 106 78 121 5.333333333 101.6666667 4.61E-18 4.243171402 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0042110///T cell activation 328845 328845 'Acsbg2' mRNA 4 4 4 0.13 0.12 0.13 0 0.03 0.03 0.126666667 0.02 0 1 1 4 0.666666667 0.188936049 -2.58994647 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016405///CoA-ligase activity+++GO:0016874///ligase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0047676///arachidonate-CoA ligase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0042759///long-chain fatty acid biosynthetic process 328918 328918 'Zscan30' mRNA 116.47 96.38 110.95 2.3 1.84 2.24 1.49 1.04 0.96 2.126666667 1.163333333 91.89 59.27 58.77 107.9333333 69.97666667 0.029603954 -0.648139537 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 328949 328949 'Mcc' mRNA 1071.3 1199.97 1078.97 6.7 7.36 7.11 6.26 5.6 5.6 7.056666667 5.82 1166.63 1007.94 999.21 1116.746667 1057.926667 0.415593868 -0.090231074 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005509///calcium ion binding GO:0010633///negative regulation of epithelial cell migration+++GO:0045184///establishment of protein localization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090090///negative regulation of canonical Wnt signaling pathway 328967 328967 'Arhgef37' mRNA 633.08 687.46 612.78 5.3 5.77 5.69 3.4 3.13 2.86 5.586666667 3.13 461.8 434.89 396.77 644.44 431.1533333 2.62E-07 -0.592776736 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 328971 328971 'Spink10' mRNA 8 10.04 11 0.16 0.08 0.09 0.02 0.05 0.09 0.11 0.053333333 3.1 4 6 9.68 4.366666667 0.265611263 -1.171345168 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 328977 328977 'Zfp532' mRNA 972 1021 1099 8.48 8.67 10.21 3.82 3.94 3.59 9.12 3.783333333 498 503 451 1030.666667 484 1.34E-23 -1.105347964 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 329002 329002 'Zfp236' mRNA 586 566 491 3.35 3.23 2.75 2.18 2.23 2.68 3.11 2.363333333 450 460 475 547.6666667 461.6666667 0.041123284 -0.255251083 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071333///cellular response to glucose stimulus 329003 329003 'Zfp516' mRNA 920.35 902.57 789.48 4.41 3.85 3.73 3.46 2.62 3.22 3.996666667 3.1 791.69 623.1 717.24 870.8 710.6766667 0.005643367 -0.304254663 04714///Thermogenesis GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0033613///activating transcription factor binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009409///response to cold+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050873///brown fat cell differentiation+++GO:0060612///adipose tissue development+++GO:0120162///positive regulation of cold-induced thermogenesis" 329015 329015 'Atg2a' mRNA 730 753 682 6.15 6.16 6.36 6.57 6.27 6.02 6.223333333 6.286666667 855 819 770 721.6666667 814.6666667 0.12531125 0.163930068 04136///Autophagy - other+++04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0034045///phagophore assembly site membrane GO:0032266///phosphatidylinositol-3-phosphate binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0044805///late nucleophagy+++GO:0061709///reticulophagy 329064 329064 'Pkd2l1' mRNA 59 87 60 0.75 1.08 0.79 0.44 0.46 0.42 0.873333333 0.44 41 42 37 68.66666667 40 0.028921568 -0.786707029 04742///Taste transduction GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034703///cation channel complex+++GO:0034704///calcium channel complex+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0005227///calcium activated cation channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005272///sodium channel activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008324///cation transmembrane transporter activity+++GO:0015269///calcium-activated potassium channel activity+++GO:0033040///sour taste receptor activity+++GO:0042802///identical protein binding+++GO:0051371///muscle alpha-actinin binding+++GO:0051393///alpha-actinin binding GO:0001581///detection of chemical stimulus involved in sensory perception of sour taste+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0007224///smoothened signaling pathway+++GO:0009415///response to water+++GO:0035725///sodium ion transmembrane transport+++GO:0050912///detection of chemical stimulus involved in sensory perception of taste+++GO:0050915///sensory perception of sour taste+++GO:0050982///detection of mechanical stimulus+++GO:0051262///protein tetramerization+++GO:0051289///protein homotetramerization+++GO:0070588///calcium ion transmembrane transport+++GO:0071467///cellular response to pH+++GO:0071468///cellular response to acidic pH+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport 329065 329065 'Scd4' mRNA 53.89 67.37 43.99 0.96 1.18 0.83 1.25 1.37 1.49 0.99 1.37 80.44 86 92.79 55.08333333 86.41 0.038732041 0.657825799 01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04212///Longevity regulating pathway - worm+++04936///Alcoholic liver disease GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0032896///palmitoyl-CoA 9-desaturase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0031670///cellular response to nutrient+++GO:0070542///response to fatty acid+++GO:1903966///monounsaturated fatty acid biosynthetic process 329093 329093 'Cpa6' mRNA 438 441 442 13.66 13.57 14.39 2.71 1.8 2.28 13.87333333 2.263333333 97 66 78 440.3333333 80.33333333 2.46E-45 -2.469370603 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 329152 329152 'Hecw2' mRNA 195 214 188 1.17 1.68 0.99 0.18 0.51 0.27 1.28 0.32 47 54 61 199 54 1.87E-16 -1.891019774 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048814///regulation of dendrite morphogenesis+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 329154 329154 'Ankrd44' mRNA 344.33 298.27 273 2.76 2.34 2.26 3.25 2.89 3.09 2.453333333 3.076666667 470.55 403 434.86 305.2 436.1366667 3.62E-04 0.503744808 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329165 329165 'Abi2' mRNA 1180.02 1162 1123.1 10.01 9.77 10.33 7.46 6.97 7.25 10.03666667 7.226666667 1006.95 926.55 938 1155.04 957.1666667 0.001236614 -0.284010837 04810///Regulation of actin cytoskeleton GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005912///adherens junction+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0031209///SCAR complex+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse GO:0017124///SH3 domain binding+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035591///signaling adaptor activity+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding GO:0007399///nervous system development+++GO:0007611///learning or memory+++GO:0008154///actin polymerization or depolymerization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016358///dendrite development+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043010///camera-type eye development+++GO:0045186///zonula adherens assembly+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0070309///lens fiber cell morphogenesis+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 329178 329178 'Unc80' mRNA 369 369 348 1.62 1.55 1.59 0.18 0.15 0.21 1.586666667 0.18 53 39 56 362 49.33333333 7.95E-48 -2.887663106 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0034703///cation channel complex GO:0005261///cation channel activity+++GO:0005515///protein binding GO:0034220///ion transmembrane transport+++GO:0055080///cation homeostasis+++GO:0098655///cation transmembrane transport 329207 329207 'Rbm44' mRNA 0 1 0 0 0.01 0 0 0 0.06 0.003333333 0.02 0 0 3 0.333333333 1 0.75009672 1.475776226 GO:0005737///cytoplasm+++GO:0045171///intercellular bridge GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity 329251 329251 'Ppp1r12b' mRNA 907 896 755 7.12 7.1 6.42 3.71 3.08 3.46 6.88 3.416666667 505 409 430 852.6666667 448 2.22E-17 -0.938743864 04270///Vascular smooth muscle contraction+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030018///Z disc+++GO:0031672///A band GO:0004857///enzyme inhibitor activity+++GO:0019208///phosphatase regulator activity+++GO:0019901///protein kinase binding GO:0007165///signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 329252 329252 'Lgr6' mRNA 1631 1813 1393 21.07 23.81 17.57 6.52 6.92 6.97 20.81666667 6.803333333 609 598 627 1612.333333 611.3333333 4.31E-52 -1.406411426 04310///Wnt signaling pathway GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0031982///vesicle GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016500///protein-hormone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0042246///tissue regeneration+++GO:1990523///bone regeneration 329260 329260 'Dennd1b' mRNA 604 513 511 4.02 3.35 3.6 3.46 3.15 3.83 3.656666667 3.48 607 533 641 542.6666667 593.6666667 0.419862559 0.117904431 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0043547///positive regulation of GTPase activity+++GO:0050776///regulation of immune response+++GO:0050790///regulation of catalytic activity+++GO:0050852///T cell receptor signaling pathway+++GO:2000553///positive regulation of T-helper 2 cell cytokine production 329274 329274 'Fam163a' mRNA 157 174 175 2.11 2.28 2.46 1.47 1.35 1.52 2.283333333 1.446666667 126 113 125 168.6666667 121.3333333 0.024738452 -0.489104301 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 329278 329278 'Tnn' mRNA 1 2 1 0.01 0.02 0.01 0 0.01 0 0.013333333 0.003333333 0 1 0 1.333333333 0.333333333 0.57610831 -1.897845056 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection+++05206///MicroRNAs in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix+++GO:0097442///CA3 pyramidal cell dendrite+++GO:1990026///hippocampal mossy fiber expansion GO:0005178///integrin binding+++GO:0042802///identical protein binding GO:0001764///neuron migration+++GO:0002076///osteoblast development+++GO:0007160///cell-matrix adhesion+++GO:0007409///axonogenesis+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0070593///dendrite self-avoidance+++GO:1905240///negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation+++GO:1990138///neuron projection extension+++GO:2001223///negative regulation of neuron migration 329324 329324 'Syt14' mRNA 1988 1878 1737 29.33 26.4 27.56 3.18 3.28 3.36 27.76333333 3.273333333 280 254 270 1867.666667 268 4.39E-197 -2.811725203 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0042802///identical protein binding 329360 329360 'Rnf224' mRNA 16 12 3 0.45 0.33 0.09 0.07 0.15 0.28 0.29 0.166666667 3 6 11 10.33333333 6.666666667 0.599266246 -0.616808518 GO:0046872///metal ion binding 329366 329366 'Ccdc187' mRNA 27 8 16 0.47 0.14 0.3 0.05 0.14 0 0.303333333 0.063333333 3 9 0 17 4 0.038226304 -2.094117905 GO:0005813///centrosome GO:0003674///molecular_function+++GO:0008017///microtubule binding GO:0008150///biological_process+++GO:0034453///microtubule anchoring 329375 329375 'Cfap77' mRNA 220 262 180 15.39 18.14 13.36 0.85 1.5 1.14 15.63 1.163333333 14 24 18 220.6666667 18.66666667 4.81E-34 -3.566852158 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329384 329384 'Ptrh1' mRNA 56.4 56.81 51 4.04 4.03 3.88 13.45 10.02 12.81 3.983333333 12.09333333 214.86 156 197.71 54.73666667 189.5233333 5.95E-14 1.785662707 GO:0005739///mitochondrion GO:0004045///aminoacyl-tRNA hydrolase activity+++GO:0016787///hydrolase activity 329416 329416 'Nostrin' mRNA 108 94 93 3.44 2.95 3.14 5.43 5.79 5.27 3.176666667 5.496666667 196 204 184 98.33333333 194.6666667 2.63E-06 0.974555937 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0003677///DNA binding+++GO:0005515///protein binding "GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0016191///synaptic vesicle uncoating+++GO:0045892///negative regulation of transcription, DNA-templated" 329421 329421 'Myo3b' mRNA 525 546 516 9.04 9.56 10.19 1.01 1.52 1.37 9.596666667 1.3 62 64 61 529 62.33333333 4.95E-76 -3.096724605 04745///Phototransduction - fly GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016459///myosin complex+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0032433///filopodium tip+++GO:0042995///cell projection GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030832///regulation of actin filament length+++GO:0046777///protein autophosphorylation+++GO:0050896///response to stimulus+++GO:0051491///positive regulation of filopodium assembly+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0090103///cochlea morphogenesis 329436 329436 'Gm14461' mRNA 224.07 241 187 7.27 7.7 6.43 0.68 0.81 1.05 7.133333333 0.846666667 24 28 36 217.3566667 29.33333333 3.79E-29 -2.895758347 329460 329460 'Olfr1193' mRNA 2 1 0 0.14 0.07 0 0 0 0 0.07 0 0 0 0 1 0 0.614783931 -2.421998967 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 329470 329470 'Accs' mRNA 172 191 177 2.32 2.61 2.56 2.66 2.85 2.54 2.496666667 2.683333333 216 223 204 180 214.3333333 0.230449759 0.240588561 GO:0005575///cellular_component GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding GO:0006520///cellular amino acid metabolic process+++GO:0008150///biological_process+++GO:0009058///biosynthetic process 329482 329482 'Dcdc5' mRNA 421 355 392 1.86 1.49 1.65 0.11 0.13 0.07 1.666666667 0.103333333 29 29 16 389.3333333 24.66666667 8.49E-62 -3.994318924 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008017///microtubule binding GO:0008150///biological_process+++GO:0035556///intracellular signal transduction+++GO:1902412///regulation of mitotic cytokinesis 329502 329502 'Pla2g4e' mRNA 59.15 71 63.72 0.57 0.7 0.73 0.2 0.14 0.19 0.666666667 0.176666667 26.1 18 23.65 64.62333333 22.58333333 7.18E-05 -1.539682115 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04072///Phospholipase D signaling pathway+++04217///Necroptosis+++04270///Vascular smooth muscle contraction+++04370///VEGF signaling pathway+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04724///Glutamatergic synapse+++04726///Serotonergic synapse+++04730///Long-term depression+++04750///Inflammatory mediator regulation of TRP channels+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04921///Oxytocin signaling pathway+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane "GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0046872///metal ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process+++GO:2001137///positive regulation of endocytic recycling 329504 329504 'Lcmt2' mRNA 513.7 539.84 528.4 8.21 8.49 8.96 9.29 10.38 10.2 8.553333333 9.956666667 669.02 729.93 711.24 527.3133333 703.3966667 3.57E-04 0.405208669 GO:0003880///protein C-terminal carboxyl O-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016740///transferase activity GO:0006481///C-terminal protein methylation+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0031591///wybutosine biosynthetic process+++GO:0032259///methylation 329506 329506 'Ctdspl2' mRNA 915.82 861.95 837.82 8.03 7.3 7.72 6.34 5.34 5.75 7.683333333 5.81 893 766 817 871.8633333 825.3333333 0.440318069 -0.090213332 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0046827///positive regulation of protein export from nucleus 329509 329509 '1810024B03Rik' mRNA 3 1 3 0.14 0.05 0.15 0.04 0 0 0.113333333 0.013333333 1 0 0 2.333333333 0.333333333 0.300797986 -2.728111845 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction 329540 329540 'Nol4l' mRNA 1247 1234 1191 11.8 11.43 11.98 7.73 6.78 7.36 11.73666667 7.29 942 802 864 1224 869.3333333 1.30E-08 -0.506454668 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0008150///biological_process 329547 329547 'Bpi' mRNA 0 0 1 0 0 0.03 0.05 0 0.06 0.01 0.036666667 2 0 2 0.333333333 1.333333333 0.60977969 1.872984808 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane GO:0001530///lipopolysaccharide binding+++GO:0008289///lipid binding GO:0006955///immune response+++GO:0019731///antibacterial humoral response+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0042742///defense response to bacterium+++GO:0043031///negative regulation of macrophage activation+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide 329554 329554 'Gm826' mRNA 2 0 2 0.15 0 0.16 0.13 0.07 0 0.103333333 0.066666667 2 1 0 1.333333333 1 0.878540591 -0.457512695 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329559 329559 'Zfp335' mRNA 856.76 806 696.02 7.64 7.11 7.08 6.49 5.79 5.57 7.276666667 5.95 757.46 672.97 648.03 786.26 692.82 0.093218637 -0.192961632 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0001701///in utero embryonic development+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0010468///regulation of gene expression+++GO:0021895///cerebral cortex neuron differentiation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048812///neuron projection morphogenesis+++GO:0048854///brain morphogenesis+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0050767///regulation of neurogenesis+++GO:0050769///positive regulation of neurogenesis+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation" 329575 329575 'Gm14325' mRNA 563.63 595.13 540.61 6.89 7.16 7.01 5.6 5.51 5.59 7.02 5.566666667 527.35 506.99 509.94 566.4566667 514.76 0.231260846 -0.150033966 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 329581 329581 'Birc7' mRNA 16 19 15 0.79 0.92 0.83 0.09 0.1 0.19 0.846666667 0.126666667 2 3 4 16.66666667 3 0.005088679 -2.48038135 04120///Ubiquitin mediated proteolysis+++04215///Apoptosis - multiple species+++05145///Toxoplasmosis+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0016740///transferase activity+++GO:0030414///peptidase inhibitor activity+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0002088///lens development in camera-type eye+++GO:0006915///apoptotic process+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051726///regulation of cell cycle+++GO:0070247///regulation of natural killer cell apoptotic process 329628 329628 'Fat4' mRNA 481 474 421 1.52 1.48 1.42 1.33 1.14 1.14 1.473333333 1.203333333 475 403 398 458.6666667 425.3333333 0.427866703 -0.120074943 04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0003007///heart morphogenesis+++GO:0007009///plasma membrane organization+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007219///Notch signaling pathway+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0035329///hippo signaling+++GO:0043931///ossification involved in bone maturation+++GO:0048565///digestive tract development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0072006///nephron development+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0098609///cell-cell adhesion 329641 329641 'Sertm1' mRNA 5 9 6 0.09 0.16 0.11 0.06 0.03 0.05 0.12 0.046666667 4 2 3 6.666666667 3 0.370356438 -1.163690114 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 329650 329650 'Med12l' mRNA 493.87 457.28 424.87 2.58 2.32 2.31 0.9 0.87 1.1 2.403333333 0.956666667 194.95 181.09 219.59 458.6733333 198.5433333 2.59E-17 -1.22017747 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 329659 329659 'E130311K13Rik' mRNA 291.01 272.56 306.95 10.39 9.6 11.58 7.31 7.58 6.99 10.52333333 7.293333333 234.91 235.5 219 290.1733333 229.8033333 0.040754297 -0.35136205 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 329679 329679 'Fnip2' mRNA 714.9 680.4 584.37 2.21 1.96 1.78 4.06 3.28 3.81 1.983333333 3.716666667 1076.76 858.17 980.01 659.89 971.6466667 2.75E-07 0.548332119 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0034451///centriolar satellite GO:0005515///protein binding+++GO:0042030///ATPase inhibitor activity+++GO:0051087///chaperone binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001932///regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0031334///positive regulation of protein complex assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043086///negative regulation of catalytic activity 329702 329702 'Dcst2' mRNA 26 14 20 0.62 0.31 0.5 0.1 0.13 0.36 0.476666667 0.196666667 5 6 17 20 9.333333333 0.152748773 -1.110815933 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 329716 329716 'BC107364' mRNA 23 24 19 0.55 0.32 0.34 0.05 0.05 0.08 0.403333333 0.06 6 6 10 22 7.333333333 0.02110546 -1.591937079 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329727 329727 'Dennd2c' mRNA 104 85 115 1.1 0.9 1.28 1.52 1.4 1.24 1.093333333 1.386666667 161 146 129 101.3333333 145.3333333 0.047380201 0.502307987 GO:0005654///nucleoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 329731 329731 'Tafa3' mRNA 371.63 457.95 378.01 4.03 4.88 4.14 0.23 0.39 0.31 4.35 0.31 28.85 45.07 36.5 402.53 36.80666667 5.25E-58 -3.475795518 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0048018///receptor ligand activity GO:0007165///signal transduction+++GO:0014016///neuroblast differentiation+++GO:1902692///regulation of neuroblast proliferation+++GO:1903979///negative regulation of microglial cell activation+++GO:1903980///positive regulation of microglial cell activation 329738 329738 'Aknad1' mRNA 43 44 35 0.84 0.7 0.74 0.26 0.39 0.09 0.76 0.246666667 15 22 5 40.66666667 14 0.0053738 -1.544219536 GO:0003674///molecular_function GO:0008150///biological_process 329739 329739 'Fam102b' mRNA 246 296 256 2.29 2.71 2.53 3.01 2.74 3.05 2.51 2.933333333 372 331 365 266 356 0.007541737 0.409060922 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329777 329777 'Pigk' mRNA 1285.98 1526.19 1517.9 17.27 22.3 21.25 25.17 23.15 25.35 20.27333333 24.55666667 1628.18 1527.36 1562.64 1443.356667 1572.726667 0.314446685 0.109778589 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042765///GPI-anchor transamidase complex GO:0003923///GPI-anchor transamidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006506///GPI anchor biosynthetic process+++GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0034394///protein localization to cell surface 329795 329795 'Tmem67' mRNA 486 586 530 7.65 9.09 8.88 4.18 4.04 3.7 8.54 3.973333333 305 286 262 534 284.3333333 7.13E-12 -0.921578231 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0031005///filamin binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0001822///kidney development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0010826///negative regulation of centrosome duplication+++GO:0030030///cell projection organization+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0035845///photoreceptor cell outer segment organization+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1904294///positive regulation of ERAD pathway 329828 329828 'Myorg' mRNA 456 470 501 5.83 5.93 6.78 3.3 2.57 2.82 6.18 2.896666667 300 225 247 475.6666667 257.3333333 9.39E-10 -0.902856832 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0048741///skeletal muscle fiber development+++GO:0051897///positive regulation of protein kinase B signaling 329831 329831 'Fam166b' mRNA 22 21 26 0.64 0.75 0.9 0.72 0.75 0.43 0.763333333 0.633333333 20 26 13 23 19.66666667 0.745429612 -0.240973048 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329839 329839 'Gm829' mRNA 4 5 1 0.23 0.28 0.06 0 0.1 0.16 0.19 0.086666667 0 2 3 3.333333333 1.666666667 0.641626695 -0.97797239 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329872 329872 'Frem1' mRNA 979 1052 784 5.46 6.09 4.65 2.44 2.36 2.42 5.4 2.406666667 507 455 468 938.3333333 476.6666667 3.34E-19 -0.984438779 04512///ECM-receptor interaction GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0007154///cell communication+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007275///multicellular organism development+++GO:0097094///craniofacial suture morphogenesis 329877 329877 'Dennd4c' mRNA 773 711 494 5.11 4.65 4.01 4.14 3.57 3.7 4.59 3.803333333 630 605 610 659.3333333 615 0.529888445 -0.104601796 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0032593///insulin-responsive compartment+++GO:0043231///intracellular membrane-bounded organelle GO:0005085///guanyl-nucleotide exchange factor activity GO:0015031///protein transport+++GO:0032483///regulation of Rab protein signal transduction+++GO:0032869///cellular response to insulin stimulus+++GO:0050790///regulation of catalytic activity+++GO:0072659///protein localization to plasma membrane 329908 329908 'Usp24' mRNA 588 648 618 3.4 3.72 3.88 3.99 3.87 3.42 3.666666667 3.76 805 754 684 618 747.6666667 0.022978331 0.26193786 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 329909 329909 'Tmem61' mRNA 22 37 15 0.88 1.47 0.64 1.57 2.04 1.23 0.996666667 1.613333333 45 57 34 24.66666667 45.33333333 0.074430015 0.880503793 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 329910 329910 'Acot11' mRNA 1240 1238.39 1269 11.68 11.45 12.64 5.77 6.05 5.47 11.92333333 5.763333333 706.53 724 650 1249.13 693.51 6.23E-20 -0.862165035 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0008289///lipid binding+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0009266///response to temperature stimulus+++GO:0009409///response to cold+++GO:0035556///intracellular signal transduction+++GO:0120163///negative regulation of cold-induced thermogenesis 329934 329934 'Foxo6' mRNA 19 18 3 0.47 0.44 0.08 0.26 0.33 0.42 0.33 0.336666667 12 15 19 13.33333333 15.33333333 0.836830189 0.216349447 04068///FoxO signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007613///memory+++GO:0060999///positive regulation of dendritic spine development" 329941 329941 'Col8a2' mRNA 429 502 308 5.33 6.13 4.06 3.31 4.43 4.13 5.173333333 3.956666667 307 401 371 413 359.6666667 0.312049187 -0.199908052 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005201///extracellular matrix structural constituent GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0048593///camera-type eye morphogenesis+++GO:0050673///epithelial cell proliferation 329942 329942 'Csmd2' mRNA 3 11 3.45 0.01 0.04 0.01 0 0 0.01 0.02 0.003333333 1 1 2 5.816666667 1.333333333 0.189068916 -2.078738494 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 329954 329954 'Catsper4' mRNA 24 10 20 0.82 0.35 0.75 0.48 0.14 0.32 0.64 0.313333333 15 4 9 18 9.333333333 0.234424442 -0.974619692 GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0048240///sperm capacitation+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 329972 329972 'Spata21' mRNA 10 4 7 0.22 0.09 0.16 0.25 0.24 0.2 0.156666667 0.23 13 12 10 7 11.66666667 0.455610194 0.72171284 GO:0005575///cellular_component GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 329977 329977 'Fhad1' mRNA 1218 1296 1125 18.29 19.42 17.66 1.95 2.24 1.95 18.45666667 2.046666667 148 163 142 1213 151 5.09E-149 -3.015421474 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 329993 329993 'Aadacl4fm5' mRNA 3 3 1 0.12 0.12 0.04 0.11 0.07 0.04 0.093333333 0.073333333 3 2 1 2.333333333 2 0.916569027 -0.222374606 GO:0005575///cellular_component GO:0016787///hydrolase activity 330010 330010 'Ttll10' mRNA 494.94 449.16 467.11 12.86 11.47 12.88 5.49 5.05 5.43 12.40333333 5.323333333 237.52 212.8 224.31 470.4033333 224.8766667 4.95E-15 -1.080279643 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097731///9+0 non-motile cilium "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070735///protein-glycine ligase activity+++GO:0070737///protein-glycine ligase activity, elongating+++GO:0070740///tubulin-glutamic acid ligase activity" GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0009566///fertilization+++GO:0018094///protein polyglycylation+++GO:0018095///protein polyglutamylation+++GO:0030317///flagellated sperm motility+++GO:0060041///retina development in camera-type eye 330050 330050 'Fam185a' mRNA 177 213 167 3.54 3.95 3.35 1.35 2.67 1.85 3.613333333 1.956666667 81 149 109 185.6666667 113 0.004541208 -0.719990789 GO:0003674///molecular_function GO:0008150///biological_process 330064 330064 'Slc5a6' mRNA 600 573 611 10.25 9.66 11.06 4.71 4.87 5.1 10.32333333 4.893333333 317 320 338 594.6666667 325 1.17E-12 -0.884936844 04977///Vitamin digestion and absorption GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0008523///sodium-dependent multivitamin transmembrane transporter activity+++GO:0015225///biotin transmembrane transporter activity+++GO:0015233///pantothenate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0015878///biotin transport+++GO:0015887///pantothenate transmembrane transport+++GO:0055085///transmembrane transport+++GO:1904200///iodide transmembrane transport+++GO:1905135///biotin import across plasma membrane 330097 330097 'Gm5108' mRNA 1 4 0 0.15 0.59 0 0 0 0.27 0.246666667 0.09 0 0 2 1.666666667 0.666666667 0.71120618 -1.288800943 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 330119 330119 'Adamts3' mRNA 32 26 16 0.25 0.21 0.15 0.11 0.21 0.24 0.203333333 0.186666667 19 19 31 24.66666667 23 0.879521288 -0.101826346 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0006508///proteolysis+++GO:0007229///integrin-mediated signaling pathway+++GO:0010573///vascular endothelial growth factor production+++GO:0016485///protein processing+++GO:0030198///extracellular matrix organization+++GO:0032964///collagen biosynthetic process+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway 330122 330122 'Cxcl3' mRNA 7 4 5 0.44 0.25 0.33 3.11 3.08 2.99 0.34 3.06 57 55 53 5.333333333 55 8.24E-10 3.3548241 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05134///Legionellosis+++05146///Amoebiasis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05323///Rheumatoid arthritis+++05417///Lipid and atherosclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity+++GO:0045236///CXCR chemokine receptor binding GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0030593///neutrophil chemotaxis+++GO:0032496///response to lipopolysaccharide+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide 330149 330149 'Hfm1' mRNA 28.09 16.99 15 0.28 0.24 0.17 0 0.04 0.04 0.23 0.026666667 0 3.88 3 20.02666667 2.293333333 6.37E-04 -3.297182032 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle 330171 330171 'Kctd10' mRNA 2041.17 2195.9 2310.38 36.14 38.26 43.39 56.84 56.45 54.56 39.26333333 55.95 3693.6 3582.98 3433.21 2182.483333 3569.93 5.00E-19 0.69518968 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0036038///MKS complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007507///heart development+++GO:0016567///protein ubiquitination+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0051260///protein homooligomerization 330173 330173 '2610524H06Rik' mRNA 619.15 576.14 557.36 42.5 39.13 40.59 40.5 41.85 43.47 40.74 41.94 676.26 681.01 701.22 584.2166667 686.1633333 0.050854796 0.221376367 GO:0005575///cellular_component+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 330177 330177 'Taok3' mRNA 778 785 717 9.43 9.35 9.34 11.43 12.39 12.06 9.373333333 11.96 1084 1146 1103 760 1111 2.84E-09 0.537819855 04010///MAPK signaling pathway GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048812///neuron projection morphogenesis 330188 330188 'Ccdc63' mRNA 0 0 2 0 0 0.08 0.03 0.03 0.03 0.026666667 0.03 1 1 1 0.666666667 1 0.880628352 0.516812859 GO:0005930///axoneme GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0036158///outer dynein arm assembly 330189 330189 'Tmem120b' mRNA 270 280 242 7.41 8.03 7.44 3.83 4.39 4.87 7.626666667 4.363333333 157 175 188 264 173.3333333 4.62E-04 -0.615509098 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity GO:0034220///ion transmembrane transport+++GO:0045444///fat cell differentiation+++GO:0051291///protein heterooligomerization 330192 330192 'Vps37b' mRNA 1355 1278 1269 30.04 27.89 29.84 20.32 20.29 19.85 29.25666667 20.15333333 1054 1028 997 1300.666667 1026.333333 3.45E-05 -0.353779902 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0048306///calcium-dependent protein binding GO:0006612///protein targeting to membrane+++GO:0006623///protein targeting to vacuole+++GO:0015031///protein transport+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:1902188///positive regulation of viral release from host cell+++GO:1903774///positive regulation of viral budding via host ESCRT complex 330216 330216 'Mblac1' mRNA 156 156 138 7.21 7.11 6.76 6.68 6.81 5.95 7.026666667 6.48 166 165 143 150 158 0.818509285 0.064872294 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process 330217 330217 'Gal3st4' mRNA 989 900 861 28.56 25.69 26.63 7.92 7.94 7.39 26.96 7.75 311 307 294 916.6666667 304 6.38E-49 -1.603174007 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process 330222 330222 'Sdk1' mRNA 1196 1216 1049 6.45 6.43 5.88 0.63 0.6 0.57 6.253333333 0.6 127 125 115 1153.666667 122.3333333 8.32E-158 -3.246860251 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0003674///molecular_function+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0010842///retina layer formation+++GO:0048148///behavioral response to cocaine+++GO:0060998///regulation of dendritic spine development 330228 330228 'Spdye4b' mRNA 0 1 2 0 0.03 0.06 0 0 0 0.03 0 0 0 0 1 0 0.596502362 -2.487866303 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0005575///cellular_component GO:0019901///protein kinase binding 330230 330230 'Zfp853' mRNA 3 7 3 0.03 0.05 0.04 0 0.02 0.01 0.04 0.01 0 2 2 4.333333333 1.333333333 0.346415541 -1.689767152 05168///Herpes simplex virus 1 infection GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity GO:0006357///regulation of transcription by RNA polymerase II 330260 330260 'Pon2' mRNA 2028 2003 1829 63.77 62.14 60.93 71.06 70.76 68.76 62.28 70.19333333 2596 2518 2432 1953.333333 2515.333333 1.05E-07 0.354202032 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004064///arylesterase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0102007///acyl-L-homoserine-lactone lactonohydrolase activity GO:0006979///response to oxidative stress+++GO:0009636///response to toxic substance+++GO:0019439///aromatic compound catabolic process 330267 330267 'Thsd7a' mRNA 320 305 262 1.52 1.42 1.32 0.59 0.72 0.55 1.42 0.62 143 171 129 295.6666667 147.6666667 1.85E-08 -1.009304136 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0098846///podocyte foot GO:0003674///molecular_function GO:0001525///angiogenesis+++GO:0030154///cell differentiation+++GO:0031532///actin cytoskeleton reorganization 330277 330277 'Fam71f1' mRNA 1 4 5 0.05 0.14 0.2 0.04 0.1 0.07 0.13 0.07 1 3 2 3.333333333 2 0.704490212 -0.755624029 GO:0003674///molecular_function GO:0008150///biological_process 330286 330286 'D630045J12Rik' mRNA 1078.74 1030.79 834.45 5.08 4.77 4.17 1.31 1.22 1.17 4.673333333 1.233333333 319.54 291.36 276.71 981.3266667 295.87 9.52E-52 -1.739581325 GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 330301 330301 'Zfp786' mRNA 239.39 240.63 164.48 1.29 1.21 1.55 0.53 0.49 0.53 1.35 0.516666667 70.97 105.78 113.82 214.8333333 96.85666667 1.17E-06 -1.159634274 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 330305 330305 'Gm5111' mRNA 131 144 148 8.77 9.54 10.51 0.06 0.06 0.06 9.606666667 0.06 1 1 1 141 1 1.41E-15 -7.153827516 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 330319 330319 'Wipf3' mRNA 530.1 544.31 461.01 6.54 6.54 6.01 2.31 1.96 2.53 6.363333333 2.266666667 219.94 179.46 228.82 511.8066667 209.4066667 1.53E-20 -1.30407057 04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005884///actin filament GO:0003779///actin binding+++GO:0017124///SH3 domain binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030048///actin filament-based movement+++GO:0030154///cell differentiation 330323 330323 'Mindy4' mRNA 415 436 402 6.17 5.91 6.37 4.99 5.12 4.88 6.15 4.996666667 416 403 353 417.6666667 390.6666667 0.50127954 -0.107897413 GO:0005575///cellular_component GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0071108///protein K48-linked deubiquitination 330355 330355 'Dnah6' mRNA 1142 1131 1028 4.77 4.63 4.55 0.59 0.79 0.62 4.65 0.666666667 161 210 165 1100.333333 178.6666667 4.49E-101 -2.631412338 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0060285///cilium-dependent cell motility 330361 330361 'Gcfc2' mRNA 88.87 111.94 63.11 1.86 2.34 1.18 0.87 1.05 1.1 1.793333333 1.006666667 56.04 66.9 66.2 87.97333333 63.04666667 0.150200064 -0.479931982 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0071008///U2-type post-mRNA release spliceosomal complex GO:0003677///DNA binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 330369 330369 'Fbxo41' mRNA 15 1 5 0.12 0.01 0.04 0.04 0.12 0.1 0.056666667 0.086666667 5 16 14 7 11.66666667 0.529383263 0.736915774 GO:0005575///cellular_component GO:0008150///biological_process 330390 330390 'Gm765' mRNA 1 4 1 0.02 0.16 0.09 0.06 0 0 0.09 0.02 4 0 0 2 1.333333333 0.843929496 -0.601993631 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 330401 330401 'Tmcc1' mRNA 432 450.85 375 3.82 3.99 3.53 3.74 3.3 3.76 3.78 3.6 489.88 414 488.03 419.2833333 463.97 0.364600645 0.13618007 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0007029///endoplasmic reticulum organization+++GO:0016197///endosomal transport+++GO:0090148///membrane fission+++GO:0097750///endosome membrane tubulation 330406 330406 'B4galnt3' mRNA 482 484 327 4.01 3.97 3.04 1.14 1.28 1.51 3.673333333 1.31 150 165 195 431 170 1.33E-14 -1.344887219 00513///Various types of N-glycan biosynthesis GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0033842///N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity 330409 330409 'Cecr2' mRNA 98 141 130 0.59 0.81 0.85 0.63 0.48 0.55 0.75 0.553333333 122 92 100 123 104.6666667 0.401517364 -0.24839363 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0031010///ISWI-type complex+++GO:0090537///CERF complex GO:0003674///molecular_function GO:0001842///neural fold formation+++GO:0001843///neural tube closure+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007338///single fertilization+++GO:0021915///neural tube development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0090102///cochlea development+++GO:0097194///execution phase of apoptosis 330450 330450 'Far2' mRNA 33.99 56.63 50.14 0.55 0.89 0.85 0.75 0.66 0.7 0.763333333 0.703333333 53.66 46.25 48.75 46.92 49.55333333 0.888448817 0.06625859 04146///Peroxisome+++04212///Longevity regulating pathway - worm GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016491///oxidoreductase activity+++GO:0080019///fatty-acyl-CoA reductase (alcohol-forming) activity+++GO:0102965///alcohol-forming fatty acyl-CoA reductase activity GO:0006629///lipid metabolic process+++GO:0010025///wax biosynthetic process+++GO:0035336///long-chain fatty-acyl-CoA metabolic process 330460 330460 'Tmem150b' mRNA 3.28 3.2 5.46 0.06 0.1 0.16 0.31 0.21 0.29 0.106666667 0.27 8 5.34 6 3.98 6.446666667 0.571064337 0.762896113 GO:0000421///autophagosome membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0010506///regulation of autophagy 330463 330463 'Zfp78' mRNA 178.31 227.09 225.19 1.75 2.22 2.35 0.93 0.92 0.95 2.106666667 0.933333333 113.9 106.56 111.27 210.1966667 110.5766667 5.59E-06 -0.947412198 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 330470 330470 'Bsph1' mRNA 0 1 0 0 0.09 0 0 0 0.08 0.03 0.026666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface GO:0008201///heparin binding GO:0007338///single fertilization+++GO:0048240///sperm capacitation 330474 330474 'Zc3h4' mRNA 1020 1050 793 8.24 8.41 6.79 5.59 6.53 6.08 7.813333333 6.066666667 797 913 846 954.3333333 852 0.16693121 -0.168820968 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0046872///metal ion binding "GO:0045892///negative regulation of transcription, DNA-templated" 330483 330483 'Ceacam16' mRNA 115.88 118.02 84.44 3.8 3.48 2.92 1.33 0.88 1.16 3.4 1.123333333 46.01 30.31 46.19 106.1133333 40.83666667 7.41E-06 -1.385302719 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0032426///stereocilium tip GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007605///sensory perception of sound 330485 330485 'Tmem145' mRNA 213 217 166 4.68 4.64 3.9 0.42 0.46 0.39 4.406666667 0.423333333 24 22 22 198.6666667 22.66666667 5.04E-30 -3.138934425 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 330502 330502 'Zfp82' mRNA 142 178 158 3.82 4.72 4.52 2.93 2.92 2.45 4.353333333 2.766666667 125 122 101 159.3333333 116 0.042934491 -0.469876564 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 330554 330554 'Fan1' mRNA 606 698 626 8.9 10.02 9.7 5.37 5.44 6.02 9.54 5.61 441 424 465 643.3333333 443.3333333 2.64E-06 -0.548377652 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0017108///5'-flap endonuclease activity+++GO:0046872///metal ion binding+++GO:0070336///flap-structured DNA binding+++GO:0140036///ubiquitin-dependent protein binding" "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0036297///interstrand cross-link repair" 330577 330577 'Saxo2' mRNA 396 433 454 6.58 7.12 7.86 1.24 1.34 1.06 7.186666667 1.213333333 92 94 76 427.6666667 87.33333333 1.45E-39 -2.306495385 GO:0005634///nucleus+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005879///axonemal microtubule+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum GO:0008017///microtubule binding GO:0034453///microtubule anchoring 330627 330627 'Trim66' mRNA 126.13 108.94 116.75 0.76 0.64 0.77 0.34 0.24 0.39 0.723333333 0.323333333 61.29 41.69 71.56 117.2733333 58.18 3.75E-04 -1.031124498 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0010369///chromocenter+++GO:0016235///aggresome GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0045892///negative regulation of transcription, DNA-templated" 330657 330657 'Prss53' mRNA 54.01 45.7 63.31 1.19 0.99 1.48 0.66 1.12 1.28 1.22 1.02 34.46 57.46 64.71 54.34 52.21 0.871519841 -0.077603371 GO:0005576///extracellular region GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 330660 330660 'Btbd16' mRNA 36.27 30.18 37.31 0.59 0.5 0.67 0.42 0.36 0.61 0.586666667 0.463333333 30.33 25.3 41.47 34.58666667 32.36666667 0.857142038 -0.117040949 GO:0003674///molecular_function GO:0008150///biological_process 330662 330662 'Dock1' mRNA 1237 1307 1222 9.59 9.96 10.05 7.05 7.13 7.25 9.866666667 7.143333333 1047 1034 1043 1255.333333 1041.333333 9.65E-04 -0.28103919 04510///Focal adhesion+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05135///Yersinia infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0032045///guanyl-nucleotide exchange factor complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0007264///small GTPase mediated signal transduction+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0050790///regulation of catalytic activity+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 330671 330671 'B4galnt4' mRNA 108 97 99 1.59 1.41 1.55 0.45 0.43 0.34 1.516666667 0.406666667 35 33 26 101.3333333 31.33333333 4.87E-08 -1.706095482 00513///Various types of N-glycan biosynthesis GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0033842///N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity 330695 330695 'Ctxn1' mRNA 867 865 803 43.25 42.61 42.5 25.08 23.8 23.64 42.78666667 24.17333333 577 534 526 845 545.6666667 9.23E-11 -0.64234846 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 330721 330721 'Nek5' mRNA 313 401 357 7.15 8.93 8.39 1.06 1.15 1.08 8.156666667 1.096666667 57 57 54 357 56 1.17E-41 -2.684320378 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051155///positive regulation of striated muscle cell differentiation+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 330723 330723 'Htra4' mRNA 1 3 6 0.03 0.08 0.16 0.3 0.16 0.33 0.09 0.263333333 14 7 14 3.333333333 11.66666667 0.093345966 1.773305782 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005520///insulin-like growth factor binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0012501///programmed cell death+++GO:0043065///positive regulation of apoptotic process 330788 330788 'Zfp866' mRNA 1014.57 1129.74 964.49 9.35 10.24 9.43 6.36 5.11 6.26 9.673333333 5.91 794 624 757.1 1036.266667 725.0333333 5.52E-07 -0.525986893 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 330790 330790 'Hapln4' mRNA 0 3 3 0 0.04 0.05 0.05 0.11 0.01 0.03 0.056666667 4 8 1 2 4.333333333 0.557038929 1.098646391 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0005540///hyaluronic acid binding GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development 330812 330812 'Rnf150' mRNA 691 669 539 4.02 3.8 3.26 1.15 1.06 0.89 3.693333333 1.033333333 205 193 178 633 192 1.01E-37 -1.729107114 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 330814 330814 'Adgrl1' mRNA 1095 927 691 7.47 6.22 5.15 4.17 3.87 4.12 6.28 4.053333333 701 635 657 904.3333333 664.3333333 6.72E-04 -0.450283033 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0015643///toxic substance binding+++GO:0016524///latrotoxin receptor activity+++GO:0030246///carbohydrate binding+++GO:0050839///cell adhesion molecule binding GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0051965///positive regulation of synapse assembly+++GO:0090129///positive regulation of synapse maturation 330817 330817 'Dhps' mRNA 849.57 856 753 38.42 38.21 36.13 31.22 35.96 31.16 37.58666667 32.78 792.52 890.55 765.01 819.5233333 816.0266667 0.911145857 -0.015249218 GO:0005737///cytoplasm GO:0016740///transferase activity+++GO:0034038///deoxyhypusine synthase activity+++GO:0042802///identical protein binding GO:0008216///spermidine metabolic process+++GO:0008612///peptidyl-lysine modification to peptidyl-hypusine+++GO:0042102///positive regulation of T cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046203///spermidine catabolic process 330830 330830 'Drc7' mRNA 641 699 680 12.4 13.33 13.94 1.17 1.2 1.26 13.22333333 1.21 69 69 72 673.3333333 70 2.35E-96 -3.278578054 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0048870///cell motility 330836 330836 'Slc7a6' mRNA 633.1 586.86 647.2 7.95 7.36 8.79 8.17 8.53 7.86 8.033333333 8.186666667 782.58 827.35 766.46 622.3866667 792.13 0.003392233 0.334527137 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015174///basic amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015807///L-amino acid transport+++GO:0015822///ornithine transport+++GO:0055085///transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1990822///basic amino acid transmembrane transport 330863 330863 'Trim67' mRNA 1 0 1 0.01 0 0.01 0.03 0.05 0.01 0.006666667 0.03 5 9 2 0.666666667 5.333333333 0.104296034 2.982706624 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0010976///positive regulation of neuron projection development+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 330890 330890 'Piwil4' mRNA 28 44 25 0.67 1.08 0.55 1 1.52 0.96 0.766666667 1.16 44 65 40 32.33333333 49.66666667 0.177942059 0.618109302 04320///Dorso-ventral axis formation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043186///P granule+++GO:0071547///piP-body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0034584///piRNA binding "GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0010669///epithelial structure maintenance+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 330908 330908 'Opcml' mRNA 63.3 69.46 45.99 0.18 0.14 0.13 0.09 0.08 0.15 0.15 0.106666667 41.74 36.73 52.63 59.58333333 43.7 0.251537767 -0.461080052 GO:0003674///molecular_function 330914 330914 'Arhgap32' mRNA 1686 1701 1444 12.88 12.75 11.72 6.01 5.59 6.26 12.45 5.953333333 924 835 951 1610.333333 903.3333333 1.26E-23 -0.843440084 GO:0000139///Golgi membrane+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0050790///regulation of catalytic activity 330921 330921 'Pate2' mRNA 5 0 0 0.13 0 0 0 0 0.05 0.043333333 0.016666667 0 0 2 1.666666667 0.666666667 0.733726654 -1.30252364 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0008150///biological_process 330938 330938 'Dixdc1' mRNA 946.98 972.74 964.84 8.14 8.12 8.67 2.66 2.5 2.42 8.31 2.526666667 364.97 335.92 318.92 961.52 339.9366667 1.46E-45 -1.516027283 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0043015///gamma-tubulin binding GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0021695///cerebellar cortex development+++GO:0021795///cerebral cortex cell migration+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021846///cell proliferation in forebrain+++GO:0021869///forebrain ventricular zone progenitor cell division+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0045665///negative regulation of neuron differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0050772///positive regulation of axonogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0070507///regulation of microtubule cytoskeleton organization 330941 330941 'AI593442' mRNA 5556 5669 5327 51.83 51.92 52.7 3.98 3.66 3.5 52.15 3.713333333 493 439 417 5517.333333 449.6666667 0 -3.629209536 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 330953 330953 'Hcn4' mRNA 26 28 35 0.21 0.22 0.3 0.03 0.04 0.06 0.243333333 0.043333333 4 6 9 29.66666667 6.333333333 5.11E-04 -2.243722624 04024///cAMP signaling pathway+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0044316///cone cell pedicle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098855///HCN channel complex GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0042802///identical protein binding+++GO:0086041///voltage-gated potassium channel activity involved in SA node cell action potential depolarization GO:0001701///in utero embryonic development+++GO:0002027///regulation of heart rate+++GO:0003254///regulation of membrane depolarization+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0008016///regulation of heart contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0071320///cellular response to cAMP+++GO:0071321///cellular response to cGMP+++GO:0071805///potassium ion transmembrane transport+++GO:0072718///response to cisplatin+++GO:0086015///SA node cell action potential+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098719///sodium ion import across plasma membrane+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:1903351///cellular response to dopamine+++GO:1990573///potassium ion import across plasma membrane 330959 330959 'Snapc5' mRNA 636 627 606 57.26 55.99 57.49 65.17 66.86 59.44 56.91333333 63.82333333 825 827 730 623 794 0.001638061 0.338253092 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0006366///transcription by RNA polymerase II+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III 330963 330963 'Ankdd1a' mRNA 25.18 8 9.05 0.23 0.07 0.1 0.21 0.16 0.13 0.133333333 0.166666667 28.93 20.02 14.49 14.07666667 21.14666667 0.486095877 0.553103472 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008150///biological_process 330998 330998 'Ankrd34c' mRNA 0 0 2 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 331004 331004 'Slc9a9' mRNA 786 726 683 12.24 11.12 11.28 12.56 11.96 12.01 11.54666667 12.17666667 928 863 859 731.6666667 883.3333333 0.009619649 0.260708563 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0055037///recycling endosome GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0035725///sodium ion transmembrane transport+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:1902600///proton transmembrane transport 331026 331026 'Gmppb' mRNA 446.44 441.89 404.09 14.57 14.2 13.91 24.17 21.64 20.94 14.22666667 22.25 856 745.53 718.71 430.8066667 773.4133333 4.36E-14 0.833229173 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0004475///mannose-1-phosphate guanylyltransferase activity+++GO:0005525///GTP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0000032///cell wall mannoprotein biosynthetic process+++GO:0006486///protein glycosylation+++GO:0009058///biosynthetic process+++GO:0009298///GDP-mannose biosynthetic process 331046 331046 'Tgm4' mRNA 17.83 18.84 37.65 0.36 0.37 0.8 0.07 0.08 0.07 0.51 0.073333333 4.11 4.27 4.04 24.77333333 4.14 7.41E-04 -2.61609211 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0062023///collagen-containing extracellular matrix "GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0018149///peptide cross-linking+++GO:0042628///mating plug formation 331063 331063 'Gsdmc2' mRNA 0 1 0 0 0.02 0 0 0.02 0 0.006666667 0.006666667 0 1.2 0 0.333333333 0.4 0.998591786 -0.011756601 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001786///phosphatidylserine binding+++GO:0003674///molecular_function+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding" GO:0012501///programmed cell death+++GO:0042742///defense response to bacterium+++GO:0060576///intestinal epithelial cell development+++GO:0070269///pyroptosis 331188 331188 'Zfp781' mRNA 295.63 305.16 298.07 3.83 3.91 4.18 2.03 1.6 2.33 3.973333333 1.986666667 181.16 143.35 198.75 299.62 174.42 5.47E-06 -0.796055301 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 331401 331401 'Thoc2' mRNA 1436 1596 1433 9.89 10.8 10.5 11.96 10.58 11.8 10.39666667 11.44666667 2001 1731 1914 1488.333333 1882 5.01E-05 0.326579629 03013///Nucleocytoplasmic transport+++03040///Spliceosome "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0016607///nuclear speck" GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0000902///cell morphogenesis+++GO:0001824///blastocyst development+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0010793///regulation of mRNA export from nucleus+++GO:0010977///negative regulation of neuron projection development+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0017145///stem cell division+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0048666///neuron development+++GO:0048699///generation of neurons+++GO:0051028///mRNA transport 331416 331416 'Gm773' mRNA 1 3 0 0.07 0.2 0 0 0 0 0.09 0 0 0 0 1.333333333 0 0.492448657 -2.82872934 GO:0000795///synaptonemal complex GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 331461 331461 'Il1rapl1' mRNA 200 196 180 1.12 1.08 1.07 0.16 0.13 0.1 1.09 0.13 33 26 20 192 26.33333333 1.94E-26 -2.878216788 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane "GO:0003953///NAD+ nucleosidase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019966///interleukin-1 binding+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007165///signal transduction+++GO:0010975///regulation of neuron projection development+++GO:0030182///neuron differentiation+++GO:0045920///negative regulation of exocytosis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051965///positive regulation of synapse assembly+++GO:0097105///presynaptic membrane assembly+++GO:0099175///regulation of postsynapse organization+++GO:0099545///trans-synaptic signaling by trans-synaptic complex+++GO:1905606///regulation of presynapse assembly 331474 331474 'Rtl5' mRNA 262.15 224.74 169.39 3.25 2.74 2.23 1.16 0.86 1.09 2.74 1.036666667 107.54 78.27 97.86 218.76 94.55666667 3.50E-08 -1.22309797 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 331487 331487 'Uprt' mRNA 81 84.98 84 0.61 0.63 0.67 1.25 0.9 0.97 0.636666667 1.04 193 135 144 83.32666667 157.3333333 1.76E-04 0.906987796 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0006222///UMP biosynthetic process+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0009116///nucleoside metabolic process+++GO:0032868///response to insulin 331491 331491 'Fnd3c2' mRNA 2 1 2 0.03 0.01 0.03 0.04 0 0.01 0.023333333 0.016666667 3 0 1 1.666666667 1.333333333 0.888247439 -0.35912679 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 331493 331493 'Gm5127' mRNA 0 4 7 0 0.13 0.22 0.17 0.14 0.14 0.116666667 0.15 6 5 5 3.666666667 5.333333333 0.764017026 0.50242696 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 331524 331524 'Xkrx' mRNA 42.13 27.25 44.19 0.63 0.43 0.66 0.17 0.38 0.27 0.573333333 0.273333333 12.86 26.46 19.25 37.85666667 19.52333333 0.061079093 -1.001235479 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 331532 331532 'Tceal5' mRNA 209.61 201.49 161.02 12.6 11.96 10.26 3.12 4.47 5.21 11.60666667 4.266666667 59.69 83.18 96.18 190.7066667 79.68333333 1.22E-07 -1.267060396 GO:0005634///nucleus GO:0003746///translation elongation factor activity+++GO:0050699///WW domain binding GO:0006414///translational elongation 331537 331537 'Dnaaf6b' mRNA 48 40 44 1.88 1.54 1.83 0.31 0.35 0.32 1.75 0.326666667 9 10 9 44 9.333333333 1.08E-05 -2.249599765 GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network GO:0045505///dynein intermediate chain binding+++GO:0051087///chaperone binding GO:0003341///cilium movement+++GO:0030317///flagellated sperm motility+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0070286///axonemal dynein complex assembly 331623 331623 'Bend3' mRNA 285.16 273.23 266.59 2.47 2.32 2.45 0.84 0.81 0.73 2.413333333 0.793333333 110.71 106.02 93.32 274.9933333 103.35 5.80E-15 -1.427019302 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000182///rDNA binding+++GO:0003677///DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000183///chromatin silencing at rDNA+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0034773///histone H4-K20 trimethylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0043967///histone H4 acetylation+++GO:0051260///protein homooligomerization+++GO:0080182///histone H3-K4 trimethylation+++GO:0098532///histone H3-K27 trimethylation+++GO:1903580///positive regulation of ATP metabolic process 332110 332110 'Mapk15' mRNA 1390 1344 507 38.78 37.81 14.47 1.87 2.54 2.86 30.35333333 2.423333333 76 103 111 1080.333333 96.66666667 6.30E-14 -3.47020309 04657///IL-17 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0072687///meiotic spindle GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000165///MAPK cascade+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003400///regulation of COPII vesicle coating+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007029///endoplasmic reticulum organization+++GO:0008156///negative regulation of DNA replication+++GO:0008284///positive regulation of cell proliferation+++GO:0010506///regulation of autophagy+++GO:0016310///phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032355///response to estradiol+++GO:0035556///intracellular signal transduction+++GO:0045732///positive regulation of protein catabolic process+++GO:0046777///protein autophosphorylation+++GO:0051973///positive regulation of telomerase activity+++GO:0090494///dopamine uptake+++GO:1902017///regulation of cilium assembly+++GO:1904355///positive regulation of telomere capping+++GO:1904491///protein localization to ciliary transition zone+++GO:1905188///positive regulation of metaphase/anaphase transition of meiosis I+++GO:1905832///positive regulation of spindle assembly 332131 332131 'Krt78' mRNA 3 0 4 0.03 0 0.05 0.07 0.07 0.07 0.026666667 0.07 7 6 7 2.333333333 6.666666667 0.295953501 1.480760254 GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 332175 332175 'Zdhhc23' mRNA 498 590 398 4.59 5.4 3.95 1.61 2.26 2.15 4.646666667 2.006666667 200 270 257 495.3333333 242.3333333 3.96E-10 -1.033701221 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0072659///protein localization to plasma membrane 332221 332221 'Zscan10' mRNA 0 1 0 0 0.02 0 0.02 0 0 0.006666667 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation" 332309 332309 'Grxcr2' mRNA 1460 1485 1427 41.61 41.69 43.14 4.36 4.29 3.79 42.14666667 4.146666667 176 169 148 1457.333333 164.3333333 3.10E-182 -3.160864725 GO:0005829///cytosol+++GO:0005902///microvillus+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0120043///stereocilium shaft+++GO:0120044///stereocilium base GO:0005515///protein binding GO:0007605///sensory perception of sound+++GO:0033365///protein localization to organelle+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060122///inner ear receptor cell stereocilium organization 332359 332359 'Tigd3' mRNA 26.03 20.02 21.03 0.69 0.52 0.59 0.81 0.89 0.65 0.6 0.783333333 35 37.91 27.58 22.36 33.49666667 0.301798914 0.552152485 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding GO:0008150///biological_process 332396 332396 'Kcnk18' mRNA 1 0 0 0.02 0 0 0.02 0 0.08 0.006666667 0.033333333 1 0 5 0.333333333 2 0.428911573 2.469780427 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0030322///stabilization of membrane potential+++GO:0071467///cellular response to pH+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane 332397 332397 'Nanos1' mRNA 36 50 14 0.5 0.68 0.2 0.26 0.34 0.41 0.46 0.336666667 22 28 33 33.33333333 27.66666667 0.705743876 -0.258144648 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0030371///translation repressor activity+++GO:0046872///metal ion binding "GO:0001558///regulation of cell growth+++GO:0001894///tissue homeostasis+++GO:0006417///regulation of translation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010631///epithelial cell migration+++GO:0016477///cell migration+++GO:0017148///negative regulation of translation+++GO:0048477///oogenesis+++GO:0098749///cerebellar neuron development+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay" 332427 332427 'Lyg2' mRNA 20 21 23 0.43 0.45 0.53 0 0 0.06 0.47 0.02 0 0 3 21.33333333 1 9.28E-05 -4.428561041 GO:0005576///extracellular region "GO:0003796///lysozyme activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0008152///metabolic process+++GO:0009253///peptidoglycan catabolic process+++GO:0016998///cell wall macromolecule catabolic process+++GO:0042742///defense response to bacterium+++GO:0050830///defense response to Gram-positive bacterium 332579 332579 'Card9' mRNA 7 9 14 0.22 0.27 0.46 2.19 1.83 1.49 0.316666667 1.836666667 82 67 54 10 67.66666667 3.56E-09 2.737176783 04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05168///Herpes simplex virus 1 infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032449///CBM complex+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0050700///CARD domain binding GO:0001819///positive regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002446///neutrophil mediated immunity+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0009410///response to xenobiotic stimulus+++GO:0009620///response to fungus+++GO:0016064///immunoglobulin mediated immune response+++GO:0032494///response to peptidoglycan+++GO:0032495///response to muramyl dipeptide+++GO:0032663///regulation of interleukin-2 production+++GO:0032675///regulation of interleukin-6 production+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032722///positive regulation of chemokine production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0042493///response to drug+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0048874///host-mediated regulation of intestinal microbiota composition+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization+++GO:0051607///defense response to virus+++GO:0061760///antifungal innate immune response+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:2000318///positive regulation of T-helper 17 type immune response 332713 332713 'Fndc11' mRNA 8 18 23 0.41 0.9 1.25 0.14 0.48 0.39 0.853333333 0.336666667 3 12.86 12.66 16.33333333 9.506666667 0.326195795 -0.875833508 GO:0003674///molecular_function GO:0008150///biological_process 332934 332934 'Zmynd12' mRNA 95 109 53 3.73 4.32 2.21 0.55 0.67 0.74 3.42 0.653333333 16 19 21 85.66666667 18.66666667 2.64E-08 -2.195661599 GO:0003674///molecular_function GO:0008150///biological_process 332937 332937 'Tfap2e' mRNA 0 1 0 0 0.03 0 0 0 0.02 0.01 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development" 332942 332942 'Ldc1' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00330///Arginine and proline metabolism+++00480///Glutathione metabolism GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004586///ornithine decarboxylase activity GO:0006596///polyamine biosynthetic process+++GO:0033387///putrescine biosynthetic process from ornithine 333048 333048 'Tmem211' mRNA 84 96 111 1.54 1.58 2.11 0.15 0.06 0.2 1.743333333 0.136666667 12 5 8 97 8.333333333 3.17E-16 -3.561470777 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 333050 333050 'Ksr2' mRNA 215 202 122 1.83 1.68 1.1 0.25 0.23 0.2 1.536666667 0.226666667 32 30 26 179.6666667 29.33333333 2.36E-19 -2.616639995 04013///MAPK signaling pathway - fly+++04014///Ras signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0016310///phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0120162///positive regulation of cold-induced thermogenesis 333088 333088 'Kcp' mRNA 8249 8391.99 7781.98 62.95 62.91 62.98 6.78 6.64 6.31 62.94666667 6.576666667 1013 974 915 8140.99 967.3333333 0 -3.084355868 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0030513///positive regulation of BMP signaling pathway 333182 333182 'Cox6b2' mRNA 150 145 136 23.36 23.24 23.18 32.88 33.43 31.8 23.26 32.70333333 220 227 208 143.6666667 218.3333333 0.001619053 0.593276223 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0030061///mitochondrial crista+++GO:0045277///respiratory chain complex IV GO:0006119///oxidative phosphorylation+++GO:0008150///biological_process 333193 333193 'Proser3' mRNA 255 221 129 5.78 4.9 3.06 2.09 2.27 1.59 4.58 1.983333333 105 112 79 201.6666667 98.66666667 6.53E-05 -1.031426546 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 333307 333307 'Trim75' mRNA 5 2 3 0.11 0.04 0.07 0.15 0.02 0 0.073333333 0.056666667 8 1 0 3.333333333 3 0.927609284 -0.185269631 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 333329 333329 'Cngb1' mRNA 13 10 11 0.34 0.19 0.28 0.1 0.19 0.21 0.27 0.166666667 8 9 11 11.33333333 9.333333333 0.773395844 -0.290892042 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04740///Olfactory transduction+++04744///Phototransduction GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017071///intracellular cyclic nucleotide activated cation channel complex+++GO:0043195///terminal bouton+++GO:1902495///transmembrane transporter complex GO:0005221///intracellular cyclic nucleotide activated cation channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0030553///cGMP binding+++GO:0043855///cyclic nucleotide-gated ion channel activity+++GO:0044877///protein-containing complex binding "GO:0001895///retina homeostasis+++GO:0006812///cation transport+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0007608///sensory perception of smell+++GO:0010628///positive regulation of gene expression+++GO:0021630///olfactory nerve maturation+++GO:0033365///protein localization to organelle+++GO:0034220///ion transmembrane transport+++GO:0035845///photoreceptor cell outer segment organization+++GO:0045494///photoreceptor cell maintenance+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051899///membrane depolarization+++GO:0098655///cation transmembrane transport+++GO:0099105///ion channel modulating, G protein-coupled receptor signaling pathway+++GO:1990834///response to odorant" 333433 333433 'Gpd1l' mRNA 1377 1274 1433 17.68 16.12 19.42 14.94 14.98 15.88 17.74 15.26666667 1334 1294 1368 1361.333333 1332 0.715065126 -0.046152808 00564///Glycerophospholipid metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009331///glycerol-3-phosphate dehydrogenase complex+++GO:0016020///membrane "GO:0004367///glycerol-3-phosphate dehydrogenase [NAD+] activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0017080///sodium channel regulator activity+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0051287///NAD binding" GO:0002027///regulation of heart rate+++GO:0005975///carbohydrate metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006116///NADH oxidation+++GO:0006734///NADH metabolic process+++GO:0010765///positive regulation of sodium ion transport+++GO:0019674///NAD metabolic process+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0046168///glycerol-3-phosphate catabolic process+++GO:0060373///regulation of ventricular cardiac muscle cell membrane depolarization+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0090038///negative regulation of protein kinase C signaling+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000649///regulation of sodium ion transmembrane transporter activity 333564 333564 'Fndc3c1' mRNA 1 0 0 0.01 0 0 0 0 0.02 0.003333333 0.006666667 0 0 2 0.333333333 0.666666667 0.863090843 0.890645578 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 333588 333588 'Gm15104' mRNA 12 3 8 0.3 0.13 0.14 0.04 0.12 0.24 0.19 0.133333333 3 3 7 7.666666667 4.333333333 0.510354267 -0.838645033 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 333605 333605 'Frmpd4' mRNA 216 217 248 1.28 1.26 1.55 0.15 0.14 0.12 1.363333333 0.136666667 29 26 24 227 26.33333333 4.92E-33 -3.12419403 GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding" GO:0051835///positive regulation of synapse structural plasticity+++GO:0098974///postsynaptic actin cytoskeleton organization 333639 333639 'Mamld1' mRNA 398 402 310 4.89 4.8 3.79 3.52 3.84 4.22 4.493333333 3.86 346 346 390 370 360.6666667 0.832371339 -0.043611973 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008584///male gonad development 333654 333654 'Ppp1r13l' mRNA 236 233 98 3.89 3.72 1.51 2.42 1.86 1.99 3.04 2.09 175 137 138 189 150 0.28589801 -0.330904022 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0045171///intercellular bridge GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0009791///post-embryonic development+++GO:0031076///embryonic camera-type eye development+++GO:0035264///multicellular organism growth+++GO:0042633///hair cycle+++GO:0045597///positive regulation of cell differentiation+++GO:0048871///multicellular organismal homeostasis+++GO:0060048///cardiac muscle contraction" 333669 333669 'Gm5134' mRNA 15 6 6 0.3 0.12 0.13 0 0.04 0.03 0.183333333 0.023333333 0 2 1 9 1 0.026486524 -3.165949184 04973///Carbohydrate digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005412///glucose:sodium symporter activity+++GO:0022857///transmembrane transporter activity GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 333670 333670 'Gm867' mRNA 23 14 10.02 0.71 0.58 0.28 1.68 2.44 1.92 0.523333333 2.013333333 55 61 61 15.67333333 59 1.56E-05 1.90946289 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 333789 333789 'N4bp2' mRNA 499.65 505.15 472.97 1.85 1.89 1.95 1.37 1.2 1.3 1.896666667 1.29 376.74 348.83 335.28 492.59 353.6166667 9.50E-05 -0.490694477 GO:0005829///cytosol GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046404///ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity GO:0016310///phosphorylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 333883 333883 'Cd59b' mRNA 94.02 95.54 93.87 7.95 7.43 7 7.74 8.15 5.82 7.46 7.236666667 104.17 96.57 94.99 94.47666667 98.57666667 0.881166998 0.047560958 04610///Complement and coagulation cascades+++04640///Hematopoietic cell lineage GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0042383///sarcolemma+++GO:0043218///compact myelin GO:0001848///complement binding GO:0001971///negative regulation of activation of membrane attack complex+++GO:0042102///positive regulation of T cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045916///negative regulation of complement activation+++GO:1903660///negative regulation of complement-dependent cytotoxicity 338320 338320 'Mia2' mRNA 676 718 469 13.13 13.61 9.63 9.93 10.13 10.48 12.12333333 10.18 590 588 598 621 592 0.681192482 -0.07258099 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070971///endoplasmic reticulum exit site GO:0038024///cargo receptor activity GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006897///endocytosis+++GO:0009306///protein secretion+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0035459///cargo loading into vesicle+++GO:0042632///cholesterol homeostasis+++GO:0042953///lipoprotein transport+++GO:0070328///triglyceride homeostasis+++GO:0070973///protein localization to endoplasmic reticulum exit site 338337 338337 'Cog3' mRNA 853 933 613 10.9 11.73 8.28 6.39 7.03 6.42 10.30333333 6.613333333 577 620 560 799.6666667 585.6666667 6.42E-04 -0.452519413 GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0017119///Golgi transport complex+++GO:0032580///Golgi cisterna membrane "GO:0006486///protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0033365///protein localization to organelle+++GO:0050821///protein stabilization" 338346 338346 'Gpr21' mRNA 8 16 11 0.2 0.39 0.29 0.32 0.22 0.29 0.293333333 0.276666667 15 10 13 11.66666667 12.66666667 0.906281965 0.107055367 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042593///glucose homeostasis+++GO:0046627///negative regulation of insulin receptor signaling pathway 338348 338348 'Ttc16' mRNA 72.02 87.04 65.05 1.43 1.7 1.39 0.42 0.33 0.21 1.506666667 0.32 25.23 18.07 12.08 74.70333333 18.46 2.82E-07 -2.036391859 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 338349 338349 'Cntln' mRNA 441 526 238 4.53 5.79 2.47 1.82 2.89 2.25 4.263333333 2.32 189 296 245 401.6666667 243.3333333 0.002531886 -0.715392781 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton "GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging" GO:0010457///centriole-centriole cohesion+++GO:0033365///protein localization to organelle 338350 338350 'Acad12' mRNA 231.8 240.15 189.95 5.46 5.57 4.74 2.63 3.18 3.02 5.256666667 2.943333333 129.04 152.21 143.38 220.6333333 141.5433333 9.32E-04 -0.644799845 GO:0005739///mitochondrion "GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding" 338351 338351 'Akap17b' mRNA 341 325 278 2.94 2.76 2.54 2.06 1.71 2.04 2.746666667 1.936666667 275 222 263 314.6666667 253.3333333 0.051501686 -0.322976113 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0051018///protein kinase A binding GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 338352 338352 'Nell1' mRNA 182 239 120 3.57 4.62 2.5 0.55 0.49 0.53 3.563333333 0.523333333 32 28 30 180.3333333 30 2.91E-18 -2.587887175 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005080///protein kinase C binding+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0045667///regulation of osteoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:1903363///negative regulation of cellular protein catabolic process 338354 338354 'Zfp780b' mRNA 766 720.16 804.54 5.74 5.22 6.64 3.97 4.39 4.69 5.866666667 4.35 592.22 631.67 668.96 763.5666667 630.95 0.016717115 -0.289931069 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 338355 338355 'Fkbp15' mRNA 785 818 825 9.12 9.13 10.05 14.75 15.18 15.86 9.433333333 15.26333333 1448 1436 1490 809.3333333 1458 5.25E-22 0.836467504 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0003779///actin binding+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006897///endocytosis+++GO:0010923///negative regulation of phosphatase activity 338359 338359 'Supv3l1' mRNA 331 400 345 7.08 8.43 7.83 7.71 6.95 7 7.78 7.22 414 365 364 358.6666667 381 0.681444303 0.075467598 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid+++GO:0045025///mitochondrial degradosome "GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016817///hydrolase activity, acting on acid anhydrides+++GO:0034458///3'-5' RNA helicase activity+++GO:0042803///protein homodimerization activity" GO:0000958///mitochondrial mRNA catabolic process+++GO:0000962///positive regulation of mitochondrial RNA catabolic process+++GO:0000965///mitochondrial RNA 3'-end processing+++GO:0006310///DNA recombination+++GO:0006401///RNA catabolic process+++GO:0030307///positive regulation of cell growth+++GO:0032508///DNA duplex unwinding+++GO:0035945///mitochondrial ncRNA surveillance+++GO:0035946///mitochondrial mRNA surveillance+++GO:0043066///negative regulation of apoptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:0070827///chromatin maintenance+++GO:2000827///mitochondrial RNA surveillance 338362 338362 'Ust' mRNA 840 883 409 10.55 10.9 5.45 3.44 3.79 4.18 8.966666667 3.803333333 315 339 371 710.6666667 341.6666667 0.001913821 -1.050872106 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0030010///establishment of cell polarity+++GO:0050770///regulation of axonogenesis 338363 338363 'Tmem241' mRNA 316.91 370.49 346.1 5.67 6.56 6.62 4.07 4.46 3.96 6.283333333 4.163333333 249.12 299.97 268.29 344.5 272.46 0.034004183 -0.349470696 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity GO:0055085///transmembrane transport 338364 338364 'Trim65' mRNA 345.05 297 223.01 4.82 4.17 3.37 5.02 3.79 4.74 4.12 4.516666667 384 289.95 363.97 288.3533333 345.9733333 0.186762649 0.252818531 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0010508///positive regulation of autophagy+++GO:0032897///negative regulation of viral transcription+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:1902187///negative regulation of viral release from host cell 338365 338365 'Slc41a2' mRNA 1110.93 1239.14 1137.52 12.06 13.46 13.26 14.62 12.55 14.69 12.92666667 13.95333333 1499.4 1281.79 1474.58 1162.53 1418.59 0.002774564 0.274724715 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008324///cation transmembrane transporter activity+++GO:0022890///inorganic cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0030001///metal ion transport+++GO:0098655///cation transmembrane transport 338366 338366 'Mia3' mRNA 2219 2338 2186.8 24.24 25.61 26.18 23.28 21.73 22.41 25.34333333 22.47333333 2492.25 2237.05 2323.63 2247.933333 2350.976667 0.541348674 0.052359753 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0038024///cargo receptor activity GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0002063///chondrocyte development+++GO:0002687///positive regulation of leukocyte migration+++GO:0006887///exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006897///endocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:0007162///negative regulation of cell adhesion+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030199///collagen fibril organization+++GO:0030336///negative regulation of cell migration+++GO:0030501///positive regulation of bone mineralization+++GO:0035459///cargo loading into vesicle+++GO:0042060///wound healing+++GO:0042953///lipoprotein transport+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:2000402///negative regulation of lymphocyte migration 338367 338367 'Myo1d' mRNA 730 682 743 8 7.07 9.01 8.77 8.04 9.17 8.026666667 8.66 834 766 882 718.3333333 827.3333333 0.10739195 0.189638614 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016459///myosin complex+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0044853///plasma membrane raft+++GO:0097440///apical dendrite GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0019904///protein domain specific binding+++GO:0030898///actin-dependent ATPase activity+++GO:0048306///calcium-dependent protein binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0010923///negative regulation of phosphatase activity+++GO:0015031///protein transport+++GO:0030050///vesicle transport along actin filament+++GO:0030900///forebrain development+++GO:0051641///cellular localization+++GO:0061502///early endosome to recycling endosome transport 338368 338368 'Pheta2' mRNA 56 71 63 1.16 1.47 1.37 1.52 1.07 1.61 1.333333333 1.4 87 57 87 63.33333333 77 0.474034004 0.267764276 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome GO:0042803///protein homodimerization activity "GO:0001881///receptor recycling+++GO:0007032///endosome organization+++GO:0042147///retrograde transport, endosome to Golgi" 338369 338369 'Tmem220' mRNA 263.71 292.77 341.83 5.16 6.33 7.28 6.44 6.89 6.74 6.256666667 6.69 367.17 356.72 373.64 299.4366667 365.8433333 0.1119153 0.27386672 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 338370 338370 'Nalcn' mRNA 1220 1243 1127 9.06 9.01 8.85 4.11 3.53 3.65 8.973333333 3.763333333 642 539 552 1196.666667 577.6666667 9.99E-30 -1.06255248 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005272///sodium channel activity+++GO:0005515///protein binding+++GO:0022840///leak channel activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0060075///regulation of resting membrane potential+++GO:0070588///calcium ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098655///cation transmembrane transport 338371 338371 'Endov' mRNA 657.54 675.94 678.98 7.77 7.85 8.79 6.79 7.46 7.18 8.136666667 7.143333333 557.66 554.08 549.39 670.82 553.71 0.01072137 -0.288716436 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule "GO:0000287///magnesium ion binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters+++GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0046872///metal ion binding" "GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 338372 338372 'Map3k9' mRNA 151 117 104 0.86 0.61 0.65 0.23 0.31 0.4 0.706666667 0.313333333 49 66 88 124 67.66666667 0.003116715 -0.878763694 04013///MAPK signaling pathway - fly+++04361///Axon regeneration GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007257///activation of JUN kinase activity+++GO:0008219///cell death+++GO:0016310///phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation 338375 338375 'Atp6v1g3' mRNA 3 5 4 0.09 0.15 0.13 0 0 0 0.123333333 0 0 0 0 4 0 0.041082801 -4.453717838 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex "GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 338403 338403 'Cndp1' mRNA 222 191 162 4.33 3.67 3.35 0.19 0.3 0.16 3.783333333 0.216666667 11 17 9 191.6666667 12.33333333 1.59E-32 -3.964478247 00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00410///beta-Alanine metabolism GO:0005829///cytosol GO:0004180///carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity GO:0006508///proteolysis+++GO:0032268///regulation of cellular protein metabolic process 338417 338417 'Scgb1c1' mRNA 97 97 104 20.74 20.84 23.63 5.66 4.48 4.13 21.73666667 4.756666667 30 23 21 99.33333333 24.66666667 9.05E-10 -2.025678133 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0008150///biological_process 338467 338467 'Morc3' mRNA 674 679 655 8.69 8.61 8.96 14.43 14.12 12.46 8.753333333 13.67 1288 1231 1077 669.3333333 1198.666667 1.14E-17 0.828355779 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix+++GO:0016605///PML body GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007569///cell aging+++GO:0009791///post-embryonic development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050821///protein stabilization+++GO:0051457///maintenance of protein location in nucleus 338521 338521 'Fa2h' mRNA 2256 2408 1651 50.45 53.02 39.17 19.54 19.61 20.06 47.54666667 19.73666667 1005 985 999 2105 996.3333333 3.58E-27 -1.083399761 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0080132///fatty acid alpha-hydroxylase activity GO:0001949///sebaceous gland cell differentiation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0006679///glucosylceramide biosynthetic process+++GO:0006682///galactosylceramide biosynthetic process+++GO:0008610///lipid biosynthetic process+++GO:0030258///lipid modification+++GO:0032286///central nervous system myelin maintenance+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0042127///regulation of cell proliferation+++GO:0042634///regulation of hair cycle+++GO:0044857///plasma membrane raft organization+++GO:0046513///ceramide biosynthetic process+++GO:0061436///establishment of skin barrier 338523 338523 'Kdm7a' mRNA 1725.54 1846.4 1096 9.46 9.95 6.75 3.69 3.73 3.69 8.72 3.703333333 713 721.02 718.78 1555.98 717.6 7.39E-18 -1.1176024 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0003712///transcription coregulator activity+++GO:0005506///iron ion binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0035575///histone demethylase activity (H4-K20 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)+++GO:0071558///histone demethylase activity (H3-K27 specific)" "GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0007399///nervous system development+++GO:0030901///midbrain development+++GO:0033169///histone H3-K9 demethylation+++GO:0035574///histone H4-K20 demethylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070544///histone H3-K36 demethylation+++GO:0071557///histone H3-K27 demethylation" 347710 347710 'Pramel4' mRNA 2 0.98 0.5 0.05 0.02 0.02 0.04 0.07 0.02 0.03 0.043333333 2 3.06 1 1.16 2.02 0.575953016 1.593718944 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 347722 347722 'Agap1' mRNA 1295 1257 1186 7.13 6.78 6.92 2.84 2.23 2.52 6.943333333 2.53 594 457 514 1246 521.6666667 1.53E-36 -1.269038674 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0005525///GTP binding+++GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 353025 353025 'Caps2' mRNA 16 12 13 0.33 0.24 0.32 0.09 0.04 0.02 0.296666667 0.05 5 2 1 13.66666667 2.666666667 0.017253603 -2.376185094 GO:0005575///cellular_component GO:0005509///calcium ion binding+++GO:0046872///metal ion binding 353047 353047 'Plekhm1' mRNA 664 601 633 5.89 5.24 5.95 9.4 8.89 8.84 5.693333333 9.043333333 1221 1128 1112 632.6666667 1153.666667 3.61E-19 0.853406662 05132///Salmonella infection GO:0005730///nucleolus+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044754///autolysosome GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0032418///lysosome localization+++GO:0035556///intracellular signal transduction+++GO:0045780///positive regulation of bone resorption+++GO:0061909///autophagosome-lysosome fusion+++GO:1900029///positive regulation of ruffle assembly+++GO:1902774///late endosome to lysosome transport 353130 353130 'Prss33' mRNA 504 571 552 19.18 21.84 22.35 23.67 26.32 26.43 21.12333333 25.47333333 690 740 738 542.3333333 722.6666667 5.12E-04 0.402321099 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0070528///protein kinase C signaling 353155 353155 'Gjd3' mRNA 37.97 46.84 39.27 0.68 0.82 0.74 0.15 0.24 0.23 0.746666667 0.206666667 9.85 15.35 14.48 41.36 13.22666667 8.48E-04 -1.690183272 GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005216///ion channel activity+++GO:0005243///gap junction channel activity+++GO:0005515///protein binding+++GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling GO:0001570///vasculogenesis+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007268///chemical synaptic transmission+++GO:0007507///heart development+++GO:0007601///visual perception+++GO:0009749///response to glucose+++GO:0010459///negative regulation of heart rate+++GO:0016264///gap junction assembly+++GO:0034220///ion transmembrane transport+++GO:0048468///cell development+++GO:0048738///cardiac muscle tissue development+++GO:0055085///transmembrane transport+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:1901845///negative regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:1903780///negative regulation of cardiac conduction 353156 353156 'Egfl7' mRNA 587 537 495 27.17 24.31 23.71 42.76 41.93 40.51 25.06333333 41.73333333 1061 1003 976 539.6666667 1013.333333 3.21E-20 0.898458541 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005112///Notch binding+++GO:0005509///calcium ion binding GO:0001525///angiogenesis+++GO:0001568///blood vessel development+++GO:0001570///vasculogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048856///anatomical structure development 353169 353169 'Slc2a12' mRNA 755.34 694.96 769.73 10.43 9.4 11.34 5.18 4.88 5.42 10.39 5.16 438.13 396.82 449.05 740.01 428 8.15E-12 -0.804439127 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport+++GO:1904659///glucose transmembrane transport 353170 353170 'Txlng' mRNA 470.22 468.38 453.38 7.24 7.22 7.5 6.27 5.65 6.25 7.32 6.056666667 449.27 391.03 419.06 463.9933333 419.7866667 0.26573928 -0.156480151 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019905///syntaxin binding+++GO:0033613///activating transcription factor binding GO:0007049///cell cycle+++GO:0010564///regulation of cell cycle process+++GO:0030500///regulation of bone mineralization+++GO:0051726///regulation of cell cycle 353172 353172 'Gars' mRNA 1520 1604 1514 35.57 36.96 37.59 38.36 41.18 39.94 36.70666667 39.82666667 1885 1976 1900 1546 1920.333333 9.06E-05 0.301710242 00970///Aminoacyl-tRNA biosynthesis GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030141///secretory granule+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0070062///extracellular exosome GO:0000166///nucleotide binding+++GO:0004081///bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004820///glycine-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006426///glycyl-tRNA aminoacylation+++GO:0015966///diadenosine tetraphosphate biosynthetic process+++GO:0070150///mitochondrial glycyl-tRNA aminoacylation 353187 353187 'Nr1d2' mRNA 2274 2532 2179 26.33 28.77 26.78 13.78 14.19 14.76 27.29333333 14.24333333 1373 1377 1424 2328.333333 1391.333333 7.25E-25 -0.752562137 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006629///lipid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0019216///regulation of lipid metabolic process+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0042752///regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048512///circadian behavior+++GO:0050727///regulation of inflammatory response+++GO:0050728///negative regulation of inflammatory response+++GO:0055088///lipid homeostasis+++GO:0097009///energy homeostasis+++GO:2001014///regulation of skeletal muscle cell differentiation" 353188 353188 'Adam32' mRNA 0 4 3 0 0.1 0.08 0.04 0.02 0.09 0.06 0.05 2 1 4 2.333333333 2.333333333 0.998591786 -0.017616633 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion+++GO:0007339///binding of sperm to zona pellucida 353190 353190 'Edc3' mRNA 729.86 736.45 722.71 11.03 11.42 11.97 11.01 10.93 10.21 11.47333333 10.71666667 817.2 784.62 714.13 729.6733333 771.9833333 0.593666253 0.06951628 03018///RNA degradation GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding+++GO:1990174///phosphodiesterase decapping endonuclease activity "GO:0031087///deadenylation-independent decapping of nuclear-transcribed mRNA+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 353208 353208 'Zfp931' mRNA 461.4 431.93 412.79 7.01 6.48 6.56 5.51 5.06 5.3 6.683333333 5.29 431.67 387.29 397.79 435.3733333 405.5833333 0.453568102 -0.113699609 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 353211 353211 'Prune2' mRNA 516 507 575 2.11 2.05 2.5 2.41 2.46 2.55 2.22 2.473333333 673 671 692 532.6666667 678.6666667 0.006557772 0.334570271 GO:0005737///cytoplasm GO:0004309///exopolyphosphatase activity+++GO:0016462///pyrophosphatase activity GO:0006798///polyphosphate catabolic process+++GO:0006915///apoptotic process 353234 353234 'Pcdha2' mRNA 12.52 13.83 23.32 0.12 0.14 0.25 0 0 0 0.17 0 0 0 0 16.55666667 0 1.58E-05 -6.470647618 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 353235 353235 'Pcdha8' mRNA 15.71 16.46 7.32 0.16 0.16 0.08 0.02 0 0 0.133333333 0.006666667 2.52 0 0 13.16333333 0.84 0.003438021 -4.253236143 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 353236 353236 'Pcdhac1' mRNA 41.57 29.69 8.61 0.42 0.29 0.09 0.02 0 0 0.266666667 0.006666667 2.48 0 0 26.62333333 0.826666667 5.75E-05 -5.280455843 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 353237 353237 'Pcdhac2' mRNA 6.81 0 11.87 0.06 0 0.12 0.56 0.32 0.22 0.06 0.366666667 68.95 38.95 26.97 6.226666667 44.95666667 3.41E-05 2.914149793 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development 353242 353242 'Mrpl21' mRNA 620 607 560 49.79 48.06 47.71 55.8 57.99 56.34 48.52 56.71 786 797 762 595.6666667 781.6666667 1.99E-04 0.381673237 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 353258 353258 'Ltv1' mRNA 349 376 400 11.1 11.9 13.5 18.4 17.16 17.7 12.16666667 17.75333333 662 601 622 375 628.3333333 3.37E-09 0.729754369 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0030688///preribosome, small subunit precursor" GO:0000056///ribosomal small subunit export from nucleus+++GO:0042274///ribosomal small subunit biogenesis 353282 353282 'Sfmbt2' mRNA 52 49 57 0.59 0.57 0.58 0.32 0.61 0.84 0.58 0.59 39 51 66 52.66666667 52 0.950460874 -0.03077022 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0042393///histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated" 353287 353287 'Clec18a' mRNA 128.09 114.68 103.16 3.53 3.13 3.02 0.64 0.6 0.38 3.226666667 0.54 26 26.06 15 115.31 22.35333333 6.19E-13 -2.374320694 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding GO:0008150///biological_process 353310 353310 'Zfp703' mRNA 217 169 138 3.72 2.85 2.49 5.45 4.65 4.93 3.02 5.01 367 305 319 174.6666667 330.3333333 3.96E-07 0.911076416 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex GO:0046872///metal ion binding+++GO:0070491///repressing transcription factor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0034111///negative regulation of homotypic cell-cell adhesion+++GO:0034333///adherens junction assembly+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0071392///cellular response to estradiol stimulus" 353326 353326 'Rtl1' mRNA 126 96 88 0.21 0.16 0.16 0.08 0.07 0.1 0.176666667 0.083333333 58 50 66 103.3333333 58 0.004378613 -0.842125318 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007275///multicellular organism development 353328 353328 'Muc6' mRNA 78.14 44.65 33.01 0.33 0.19 0.18 0.22 0.16 0.23 0.233333333 0.203333333 57.84 42.48 56.81 51.93333333 52.37666667 0.998591786 -0.004505195 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030277///maintenance of gastrointestinal epithelium 353346 353346 'Gpr141' mRNA 3 2 6 0.05 0.03 0.09 0.95 1.1 1.32 0.056666667 1.123333333 70 80 95 3.666666667 81.66666667 4.38E-15 4.461880747 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 353371 353371 'Oxct2b' mRNA 4.52 1 2 0.15 0.03 0.07 0.03 0.06 0.03 0.083333333 0.04 1 2 1 2.506666667 1.333333333 0.733152443 -0.814389095 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism" GO:0005739///mitochondrion+++GO:0031514///motile cilium GO:0008260///3-oxoacid CoA-transferase activity+++GO:0008410///CoA-transferase activity+++GO:0016740///transferase activity GO:0006091///generation of precursor metabolites and energy+++GO:0046950///cellular ketone body metabolic process+++GO:0046952///ketone body catabolic process 353499 353499 'Tmc4' mRNA 2021 1874 1903 48.27 44.07 48.21 41.47 41.98 42.95 46.85 42.13333333 1997 1974 2002 1932.666667 1991 0.760796544 0.030706679 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 353502 353502 'Hcfc1r1' mRNA 1363.67 1419.11 1340.77 72.85 75.44 74.01 100.13 104.4 92.25 74.1 98.92666667 1978.06 2022.84 1805.02 1374.516667 1935.306667 9.51E-10 0.48254994 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 360013 360013 'Myo18a' mRNA 1346 1476 1320 9.55 10.16 10.04 10.33 9.61 9.83 9.916666667 9.923333333 1652 1514 1533 1380.666667 1566.333333 0.039998752 0.170617589 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0042641///actomyosin+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0043531///ADP binding+++GO:0051015///actin filament binding+++GO:0060090///molecular adaptor activity GO:0007030///Golgi organization+++GO:0016477///cell migration+++GO:0031032///actomyosin structure organization+++GO:0043030///regulation of macrophage activation+++GO:0043066///negative regulation of apoptotic process+++GO:0048194///Golgi vesicle budding+++GO:0050714///positive regulation of protein secretion+++GO:0071346///cellular response to interferon-gamma+++GO:0090161///Golgi ribbon formation+++GO:0090164///asymmetric Golgi ribbon formation+++GO:1903028///positive regulation of opsonization 360213 360213 'Trim46' mRNA 173.44 174.28 155.62 3.25 3.35 3.17 2 2.33 1.82 3.256666667 2.05 126.34 138 105 167.78 123.1133333 0.04278042 -0.453668552 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0044304///main axon+++GO:1904115///axon cytoplasm+++GO:1990769///proximal neuron projection GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0001764///neuron migration+++GO:0007409///axonogenesis+++GO:0030517///negative regulation of axon extension+++GO:0032880///regulation of protein localization+++GO:0048490///anterograde synaptic vesicle transport+++GO:0099612///protein localization to axon+++GO:1901953///positive regulation of anterograde dense core granule transport+++GO:1903827///regulation of cellular protein localization 360216 360216 'Zranb1' mRNA 665 728 663 7.8 8.47 8 5.65 4.9 5.27 8.09 5.273333333 570 490 520 685.3333333 526.6666667 4.46E-04 -0.392141374 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006508///proteolysis+++GO:0007010///cytoskeleton organization+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0022604///regulation of cell morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0035523///protein K29-linked deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:1990168///protein K33-linked deubiquitination 360220 360220 'Speer4d' mRNA 1.28 1.19 1.33 0.07 0.06 0.08 0 0 0 0.07 0 0 0 0 1.266666667 0 0.568344116 -2.455252046 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 368202 368202 'Prss48' mRNA 4 10 3 0.21 0.51 0.17 0.12 0.48 0.36 0.296666667 0.32 2 10 7 5.666666667 6.333333333 0.897108097 0.176035994 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 368203 368203 'Gm5136' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 03440///Homologous recombination+++04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0070531///BRCA1-A complex+++GO:0070552///BRISC complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006508///proteolysis+++GO:0010212///response to ionizing radiation+++GO:0045739///positive regulation of DNA repair+++GO:0070536///protein K63-linked deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint 373864 373864 'Col27a1' mRNA 3197 3243 2562 30.05 30.6 27.69 11.26 13.8 14.55 29.44666667 13.20333333 1397 1577 1664 3000.666667 1546 1.45E-27 -0.962354968 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005583///fibrillar collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0046872///metal ion binding GO:0003431///growth plate cartilage chondrocyte development+++GO:0030198///extracellular matrix organization 378425 378425 'Nlrp12' mRNA 0 0 3 0 0 0.04 0.01 0.03 0.03 0.013333333 0.023333333 1 3 3 1 2.333333333 0.661394766 1.164763308 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0001818///negative regulation of cytokine production+++GO:0009968///negative regulation of signal transduction+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0036336///dendritic cell migration+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045751///negative regulation of Toll signaling pathway+++GO:0050728///negative regulation of inflammatory response+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071345///cellular response to cytokine stimulus+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 378431 378431 'Txlnb' mRNA 62 64 76 0.75 0.76 0.97 0.38 0.21 0.27 0.826666667 0.286666667 36 20 25 67.33333333 27 5.41E-04 -1.339143689 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0019905///syntaxin binding GO:0008150///biological_process 378435 378435 'Mafa' mRNA 0 3 0 0 0.06 0 0 0.03 0 0.02 0.01 0 2 0 1 0.666666667 0.895707484 -0.532941964 04930///Type II diabetes mellitus+++04950///Maturity onset diabetes of the young GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007263///nitric oxide mediated signal transduction+++GO:0009749///response to glucose+++GO:0030073///insulin secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 378460 378460 'Pram1' mRNA 66 60 66 1.63 1.46 1.73 2.38 2.39 2.08 1.606666667 2.283333333 111 109 94 64 104.6666667 0.013125644 0.69603948 GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0008289///lipid binding+++GO:0019901///protein kinase binding GO:0007229///integrin-mediated signaling pathway+++GO:0043313///regulation of neutrophil degranulation+++GO:0050852///T cell receptor signaling pathway+++GO:0072659///protein localization to plasma membrane 378462 378462 'Morn2' mRNA 1107 1044 1087.01 123.59 115.38 129.33 51.47 50.8 45.11 122.7666667 49.12666667 528.6 501 449.68 1079.336667 493.0933333 9.36E-29 -1.14504165 GO:0001669///acrosomal vesicle+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 378466 378466 'Gm10033' mRNA 320 327 364 2.98 3 3.6 2.4 2.19 2.32 3.193333333 2.303333333 296 264 278 337 279.3333333 0.081604724 -0.286550782 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 378700 378700 'Bpifb3' mRNA 0 3 9 0 0.1 0.32 0.26 0.18 0.06 0.14 0.166666667 9 6 2 4 5.666666667 0.800882498 0.446865581 GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0008289///lipid binding GO:0008150///biological_process+++GO:0045087///innate immune response 378702 378702 'Serf2' mRNA 5435.72 5415.79 5483.92 97.64 95.74 104.5 118.17 131.19 122.63 99.29333333 123.9966667 7568.58 8206.23 7605.07 5445.143333 7793.293333 1.41E-14 0.505287687 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0031648///protein destabilization 378937 378937 'Lrrc24' mRNA 144 127 115 4.33 3.76 3.67 0.92 0.78 0.95 3.92 0.883333333 35 29 35 128.6666667 33 5.42E-12 -1.973283282 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0051965///positive regulation of synapse assembly 379043 379043 'Raet1e' mRNA 2 1 0 0.09 0.05 0 2.92 3.96 2.93 0.046666667 3.27 73.69 97.51 71.99 1 81.06333333 1.32E-11 6.322414001 04650///Natural killer cell mediated cytotoxicity GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0044214///spanning component of plasma membrane+++GO:0046658///anchored component of plasma membrane GO:0046703///natural killer cell lectin-like receptor binding GO:0001913///T cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 380601 380601 'Fastkd5' mRNA 272.09 221.52 221.07 4.88 3.9 4.23 3.81 4.08 4.16 4.336666667 4.016666667 243.4 257.13 257.21 238.2266667 252.58 0.747182067 0.074269373 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid GO:0003723///RNA binding+++GO:0019843///rRNA binding GO:0000963///mitochondrial RNA processing+++GO:0006397///mRNA processing+++GO:0044528///regulation of mitochondrial mRNA stability 380608 380608 'Tagap1' mRNA 253.37 252.34 242.16 5.75 5.55 5.79 4.81 3.59 5.21 5.696666667 4.536666667 234.67 174.74 246.88 249.29 218.7633333 0.320948454 -0.205047042 GO:0005575///cellular_component GO:0005096///GTPase activator activity GO:0050790///regulation of catalytic activity 380614 380614 'Intu' mRNA 641.46 657.54 629.74 5.73 5.89 5.81 2.27 2.33 1.94 5.81 2.18 299.52 294.98 265.08 642.9133333 286.5266667 9.92E-23 -1.179269492 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0001736///establishment of planar polarity+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016192///vesicle-mediated transport+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0021915///neural tube development+++GO:0030030///cell projection organization+++GO:0030216///keratinocyte differentiation+++GO:0030278///regulation of ossification+++GO:0031069///hair follicle morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0043587///tongue morphogenesis+++GO:0044458///motile cilium assembly+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051782///negative regulation of cell division+++GO:0060021///roof of mouth development+++GO:0060173///limb development+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 380629 380629 'Heca' mRNA 198 158 194 2.26 1.78 2.35 2.03 2.25 1.93 2.13 2.07 204 221 188 183.3333333 204.3333333 0.556345946 0.142181241 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0045930///negative regulation of mitotic cell cycle 380654 380654 'Cfap54' mRNA 1113 1052 931 6.04 5.46 5.41 1.42 1.34 1.49 5.636666667 1.416666667 295 281 284 1032 286.6666667 2.78E-68 -1.857604261 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0090660///cerebrospinal fluid circulation 380660 380660 'Acss3' mRNA 1736 1852 1811 20.98 22.37 23.57 10.61 9.77 11.43 22.30666667 10.60333333 1007 873 975 1799.666667 951.6666667 1.29E-28 -0.932798359 00640///Propanoate metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003987///acetate-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0047760///butyrate-CoA ligase activity+++GO:0050218///propionate-CoA ligase activity GO:0008150///biological_process 380664 380664 'Lemd3' mRNA 208 162 188 2.35 1.8 2.25 2.72 1.82 2.68 2.133333333 2.406666667 277 181 265 186 241 0.106764375 0.357243318 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding GO:0001525///angiogenesis+++GO:0002044///blood vessel endothelial cell migration involved in intussusceptive angiogenesis+++GO:0006997///nucleus organization+++GO:0006998///nuclear envelope organization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0035914///skeletal muscle cell differentiation+++GO:0051726///regulation of cell cycle+++GO:1902531///regulation of intracellular signal transduction+++GO:1903053///regulation of extracellular matrix organization 380669 380669 'Lin28b' mRNA 25 29 25 0.19 0.19 0.24 0 0 0 0.206666667 0 0 0 0 26.33333333 0 2.03E-07 -7.171832718 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0010587///miRNA catabolic process+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0050779///RNA destabilization+++GO:2000627///positive regulation of miRNA catabolic process+++GO:2000632///negative regulation of pre-miRNA processing+++GO:2000635///negative regulation of primary miRNA processing 380684 380684 'Nefh' mRNA 6 4 4.38 0.08 0.05 0.06 0.06 0.02 0.12 0.063333333 0.066666667 5 2 10 4.793333333 5.666666667 0.863090843 0.269144012 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005883///neurofilament+++GO:0014069///postsynaptic density+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0097418///neurofibrillary tangle+++GO:0097440///apical dendrite+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099160///postsynaptic intermediate filament cytoskeleton+++GO:0150017///basal proximal dendrite "GO:0005200///structural constituent of cytoskeleton+++GO:0015643///toxic substance binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0044877///protein-containing complex binding+++GO:0099184///structural constituent of postsynaptic intermediate filament cytoskeleton" GO:0000226///microtubule cytoskeleton organization+++GO:0001552///ovarian follicle atresia+++GO:0007420///brain development+++GO:0031103///axon regeneration+++GO:0033693///neurofilament bundle assembly+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045110///intermediate filament bundle assembly+++GO:0048936///peripheral nervous system neuron axonogenesis+++GO:0060052///neurofilament cytoskeleton organization+++GO:0061564///axon development+++GO:0099185///postsynaptic intermediate filament cytoskeleton organization+++GO:1902513///regulation of organelle transport along microtubule+++GO:1903935///response to sodium arsenite+++GO:1990830///cellular response to leukemia inhibitory factor 380686 380686 'Cnrip1' mRNA 92 130 119 3.33 4.64 4.57 8.89 9.69 9.06 4.18 9.213333333 282 300 278 113.6666667 286.6666667 3.90E-12 1.322539555 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043209///myelin sheath GO:0008022///protein C-terminus binding+++GO:0031718///type 1 cannabinoid receptor binding GO:0010469///regulation of signaling receptor activity+++GO:2000272///negative regulation of signaling receptor activity 380694 380694 'Ccnjl' mRNA 220 205 169 4.49 4.12 3.66 0.76 0.65 0.77 4.09 0.726666667 43 36 42 198 40.33333333 2.94E-21 -2.304021628 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0044772///mitotic cell cycle phase transition 380698 380698 'Obscn' mRNA 124 86 88 0.27 0.18 0.2 0.04 0.04 0.07 0.216666667 0.05 23 19 35 99.33333333 25.66666667 2.69E-08 -1.962219188 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005863///striated muscle myosin thick filament+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0042383///sarcolemma "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0008307///structural constituent of muscle+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030506///ankyrin binding+++GO:0031432///titin binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0046777///protein autophosphorylation+++GO:0050790///regulation of catalytic activity 380701 380701 'Slc47a2' mRNA 7 5 5 0.19 0.12 0.12 0.05 0.1 0.13 0.143333333 0.093333333 2 5 6 5.666666667 4.333333333 0.793064309 -0.390607826 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity GO:0055085///transmembrane transport+++GO:1990961///drug transmembrane export 380702 380702 'Shisa6' mRNA 343 314 319 2.37 2.11 2.33 0.24 0.13 0.18 2.27 0.183333333 39 20 30 325.3333333 29.66666667 8.45E-49 -3.46975021 "GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0032591///dendritic spine membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0098985///asymmetric, glutamatergic, excitatory synapse+++GO:0099061///integral component of postsynaptic density membrane" GO:0030165///PDZ domain binding+++GO:0035255///ionotropic glutamate receptor binding GO:0007283///spermatogenesis+++GO:0016055///Wnt signaling pathway+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0098976///excitatory chemical synaptic transmission+++GO:1904717///regulation of AMPA glutamate receptor clustering+++GO:2000311///regulation of AMPA receptor activity 380705 380705 'Tmem102' mRNA 238 264 285 7 7.66 8.9 7.99 8.05 7.91 7.853333333 7.983333333 312 307 299 262.3333333 306 0.249267912 0.207255004 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0034097///response to cytokine+++GO:0042981///regulation of apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:1901028///regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:2000406///positive regulation of T cell migration 380709 380709 'Spata22' mRNA 0 0 1 0 0 0.03 0 0.04 0 0.01 0.013333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005694///chromosome GO:0005515///protein binding GO:0000711///meiotic DNA repair synthesis+++GO:0007129///synapsis+++GO:0007276///gamete generation+++GO:0009566///fertilization+++GO:0048137///spermatocyte division+++GO:0051321///meiotic cell cycle+++GO:0051445///regulation of meiotic cell cycle+++GO:0060631///regulation of meiosis I+++GO:0061458///reproductive system development 380711 380711 'Rap1gap2' mRNA 68 71 64 0.58 0.58 0.59 0.92 1.02 0.82 0.583333333 0.92 122 137 110 67.66666667 123 0.001085921 0.852395127 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031965///nuclear membrane+++GO:0043005///neuron projection GO:0005096///GTPase activator activity GO:0008361///regulation of cell size+++GO:0010977///negative regulation of neuron projection development+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity 380712 380712 'Tlcd2' mRNA 214.99 214 193.15 9.18 9.11 8.69 14.01 13.49 12.82 8.993333333 13.44 374 348 335 207.38 352.3333333 4.36E-07 0.756414692 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007009///plasma membrane organization+++GO:0055088///lipid homeostasis+++GO:0055091///phospholipid homeostasis+++GO:0071709///membrane assembly+++GO:0097035///regulation of membrane lipid distribution 380713 380713 'Scarf1' mRNA 156 148 172 2.98 2.78 3.48 6.49 6.54 6.67 3.08 6.566666667 391 385 389 158.6666667 388.3333333 5.42E-16 1.276792888 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0030169///low-density lipoprotein particle binding GO:0006898///receptor-mediated endocytosis+++GO:0007155///cell adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0016322///neuron remodeling+++GO:0016358///dendrite development+++GO:0048680///positive regulation of axon regeneration 380714 380714 'Rph3al' mRNA 1642 1618 1237 44.42 42.71 36.43 5.12 5.94 5.8 41.18666667 5.62 218 246 234 1499 232.6666667 2.11E-121 -2.693059503 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0030274///LIM domain binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0017157///regulation of exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0032024///positive regulation of insulin secretion+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050714///positive regulation of protein secretion 380718 380718 'Mks1' mRNA 505 532 522 11.26 11.81 12.35 5.08 5.54 5.74 11.80666667 5.453333333 262 279 278 519.6666667 273 4.73E-13 -0.940579787 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding "GO:0001843///neural tube closure+++GO:0003271///smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation+++GO:0007368///determination of left/right symmetry+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010669///epithelial structure maintenance+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0044458///motile cilium assembly+++GO:0048706///embryonic skeletal system development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:0060411///cardiac septum morphogenesis+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061009///common bile duct development+++GO:1901620///regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1905515///non-motile cilium assembly+++GO:1990403///embryonic brain development+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway" 380728 380728 'Kcnh4' mRNA 0 0 1 0 0 0.02 0.02 0.03 0 0.006666667 0.016666667 1 2 0 0.333333333 1 0.728867167 1.474605776 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 380730 380730 'Gm884' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 380732 380732 'Milr1' mRNA 66 63 48 2.94 2.72 2.41 17.52 18.56 19.29 2.69 18.45666667 476 503 502.98 59 493.9933333 4.52E-67 3.057012427 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0007166///cell surface receptor signaling pathway+++GO:0033004///negative regulation of mast cell activation+++GO:0043303///mast cell degranulation+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules 380752 380752 'Eipr1' mRNA 517 588 548 17.61 20.41 21.18 18.76 19.85 17.91 19.73333333 18.84 629 644 564 551 612.3333333 0.298069893 0.140478358 GO:0000938///GARP complex+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:1990745///EARP complex GO:0003674///molecular_function "GO:0016567///protein ubiquitination+++GO:0032456///endocytic recycling+++GO:0050796///regulation of insulin secretion+++GO:1904811///positive regulation of dense core granule transport+++GO:1905281///positive regulation of retrograde transport, endosome to Golgi+++GO:2001137///positive regulation of endocytic recycling" 380753 380753 'Atxn7l1' mRNA 644 745 592 14.14 15.82 14.1 16.78 15.12 16.24 14.68666667 16.04666667 797 711 747 660.3333333 751.6666667 0.129181267 0.177442813 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 380755 380755 'Lsmem1' mRNA 5 2 2 0.25 0.1 0.11 0.13 0.18 0.14 0.153333333 0.15 3 4 3 3 3.333333333 0.933666469 0.148918502 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 380768 380768 'Ccdc177' mRNA 10 9 5 0.12 0.11 0.06 0.01 0.04 0.05 0.096666667 0.033333333 1 4 5 8 3.333333333 0.305694308 -1.256354094 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 380773 380773 'Slirp' mRNA 718.96 809 967.93 166.1 188.13 237.6 173.56 182.26 183.38 197.2766667 179.7333333 850 863.98 862 831.9633333 858.66 0.863672516 0.028217528 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0036126///sperm flagellum+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0007286///spermatid development+++GO:0007338///single fertilization+++GO:0030317///flagellated sperm motility+++GO:0070584///mitochondrion morphogenesis 380785 380785 'Begain' mRNA 114 104 58 2.36 2.12 1.27 0.34 0.79 0.48 1.916666667 0.536666667 19 43 26 92 29.33333333 2.66E-05 -1.643200715 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003674///molecular_function GO:0098817///evoked excitatory postsynaptic potential+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity 380787 380787 'Lbhd2' mRNA 0 5 0 0 0.54 0 1.61 1.83 1.57 0.18 1.67 17 19 16 1.666666667 17.33333333 0.001881197 3.388674262 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 380836 380836 'Mrs2' mRNA 966.11 953.9 846.42 10.26 10.3 9.28 12.32 11.04 11.2 9.946666667 11.52 1117.88 921.28 987.21 922.1433333 1008.79 0.280574158 0.118303983 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015095///magnesium ion transmembrane transporter activity GO:0006089///lactate metabolic process+++GO:0006811///ion transport+++GO:0015693///magnesium ion transport+++GO:0045016///mitochondrial magnesium ion transmembrane transport 380839 380839 'Serpinb1c' mRNA 2 0 0 0.08 0 0 0.25 0.33 0.17 0.026666667 0.25 8 10 5.29 0.666666667 7.763333333 0.03357454 3.52347568 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0044342///type B pancreatic cell proliferation 380840 380840 'Lyrm4' mRNA 891 826 861 34.7 31.73 35.57 18.99 20.43 21.06 34 20.16 560 588 601 859.3333333 583 5.75E-08 -0.571947043 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0016604///nuclear body+++GO:1990221///L-cysteine desulfurase complex GO:0003674///molecular_function GO:0016226///iron-sulfur cluster assembly 380842 380842 'Stmnd1' mRNA 3 1 0 0.13 0.04 0 0.12 0.08 0 0.056666667 0.066666667 3 2 0 1.333333333 1.666666667 0.905734546 0.328478116 GO:0005737///cytoplasm+++GO:0043005///neuron projection GO:0015631///tubulin binding GO:0007019///microtubule depolymerization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031175///neuron projection development 380845 380845 'Gm904' mRNA 53 55 71 6.02 6.21 8.56 0.7 0.61 0.83 6.93 0.713333333 7 6 8 59.66666667 7 8.19E-10 -3.110921009 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 380850 380850 'Gm5141' mRNA 168 200.41 249.15 2.8 3.28 4.4 2.37 2.42 1.82 3.493333333 2.203333333 164.03 163.23 122 205.8533333 149.7533333 0.045285789 -0.478407943 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 380855 380855 'Rsl1' mRNA 71.33 79.27 88.62 1.98 2.17 2.61 2.36 2.14 1.52 2.253333333 2.006666667 97.57 86.52 60.99 79.74 81.69333333 0.979686807 0.012700148 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007530///sex determination+++GO:0044030///regulation of DNA methylation+++GO:0045892///negative regulation of transcription, DNA-templated" 380863 380863 'Tmem171' mRNA 288 255 194 14.2 12.5 10.7 9.01 12.94 13.39 12.46666667 11.78 198 290 291 245.6666667 259.6666667 0.776510897 0.077901413 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 380882 380882 'Gm906' mRNA 34.48 42.19 35.92 0.6 0.72 0.66 0 0 0.13 0.66 0.043333333 0 0 8.6 37.53 2.866666667 0.029567584 -3.798074881 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 380912 380912 'Zfp395' mRNA 980 1046 739 12.34 12.92 9.91 6.85 6.85 6.25 11.72333333 6.65 626 611 555 921.6666667 597.3333333 6.99E-08 -0.631270412 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 380916 380916 'Lrch1' mRNA 738 775 740 8.6 8.89 9.13 9.52 9.16 9.25 8.873333333 9.31 941 882 886 751 903 0.00997848 0.253671054 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0034260///negative regulation of GTPase activity+++GO:1990869///cellular response to chemokine+++GO:2000405///negative regulation of T cell migration 380918 380918 'Siah3' mRNA 43 39 51 3.12 2.8 3.92 0.13 0.13 0.13 3.28 0.13 2 2 2 44.33333333 2 4.78E-09 -4.488542997 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1903215///negative regulation of protein targeting to mitochondrion 380921 380921 'Dgkh' mRNA 258.34 250.37 263.61 0.74 0.74 0.85 0.53 0.6 0.43 0.776666667 0.52 199.22 213.69 162.43 257.44 191.78 0.019148315 -0.438756233 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019900///kinase binding+++GO:0032093///SAM domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006654///phosphatidic acid biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0046339///diacylglycerol metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation 380924 380924 'Olfm4' mRNA 355 375 331 7.13 7.41 7.05 0.3 0.34 0.36 7.196666667 0.333333333 17 19 20 353.6666667 18.66666667 3.41E-63 -4.253792413 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0042581///specific granule+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding GO:0007155///cell adhesion+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050777///negative regulation of immune response+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 380928 380928 'Lmo7' mRNA 2406 2412 2324 23.21 22.65 23.59 3.52 3.54 3.4 23.15 3.486666667 420 405 394 2380.666667 406.3333333 9.72E-214 -2.562660901 04520///Adherens junction GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane GO:0008022///protein C-terminus binding+++GO:0042805///actinin binding+++GO:0046872///metal ion binding GO:0023051///regulation of signaling+++GO:0030155///regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II 380959 380959 'Alg10b' mRNA 1646 1515 755 23.93 21.67 11.64 10.06 15.56 12.89 19.08 12.83666667 796 1203 988 1305.333333 995.6666667 0.385612943 -0.382369739 00510///N-Glycan biosynthesis GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0106073///dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001662///behavioral fear response+++GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006487///protein N-linked glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0008542///visual learning+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048706///embryonic skeletal system development+++GO:0060117///auditory receptor cell development+++GO:0071805///potassium ion transmembrane transport" 380967 380967 'Tmem106c' mRNA 4056.87 4160.08 3900.76 127.07 130.85 132.55 74.17 71.95 72.11 130.1566667 72.74333333 2696.95 2569.71 2553.06 4039.236667 2606.573333 2.10E-28 -0.643695663 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 380969 380969 'Nckap5l' mRNA 208 216 210 2.29 2.34 2.46 2.58 2 2.25 2.363333333 2.276666667 270 204 228 211.3333333 234 0.540777146 0.132728872 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0035371///microtubule plus-end GO:0003674///molecular_function GO:0001578///microtubule bundle formation+++GO:0007019///microtubule depolymerization 380993 380993 'Zfat' mRNA 165 126 125 1.96 1.47 1.58 1.87 1.68 1.87 1.67 1.806666667 181 159 174 138.6666667 171.3333333 0.205015449 0.294253551 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030097///hemopoiesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060712///spongiotrophoblast layer development" 381022 381022 'Kmt2d' mRNA 5802 5263 4300 15.06 13.41 11.82 9.24 8.82 9.45 13.43 9.17 4117 3837 4060 5121.666667 4004.666667 3.62E-06 -0.362249902 00310///Lysine degradation+++04934///Cushing syndrome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042393///histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding" GO:0001555///oocyte growth+++GO:0001701///in utero embryonic development+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0016571///histone methylation+++GO:0031507///heterochromatin assembly+++GO:0032259///methylation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0034968///histone lysine methylation+++GO:0043627///response to estrogen+++GO:0044648///histone H3-K4 dimethylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis+++GO:0051568///histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0097692///histone H3-K4 monomethylation 381038 381038 'Parl' mRNA 1134 1063 1104 51.7 47.83 53.4 49.08 53.57 48.61 50.97666667 50.42 1236 1316 1184 1100.333333 1245.333333 0.097249026 0.166312783 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0008053///mitochondrial fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0030162///regulation of proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 381045 381045 'Ccdc58' mRNA 145 168 207 8.81 9.53 13.26 12.84 11.09 13.36 10.53333333 12.43 238 207 214 173.3333333 219.6666667 0.146767575 0.322381708 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0003674///molecular_function GO:0008150///biological_process 381058 381058 'Unc93a' mRNA 3.36 1.2 0 0.09 0.02 0 0.02 0 0.02 0.036666667 0.013333333 1 0 1 1.52 0.666666667 0.775375801 -0.992794393 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381059 381059 'Gm1604b' mRNA 1 0 1 0.09 0 0.09 0 0.08 0.08 0.06 0.053333333 0 1 1 0.666666667 0.666666667 0.998591786 -0.018390223 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381062 381062 'Ermard' mRNA 666.55 708.97 633.5 10.72 11.16 11.1 11.46 11.15 9.17 10.99333333 10.59333333 760.73 694.17 606.33 669.6733333 687.0766667 0.863090843 0.026076237 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381066 381066 'Zfp948' mRNA 180 219 226 3.49 4.25 4.82 6.36 5.44 4.99 4.186666667 5.596666667 368 306 280 208.3333333 318 9.28E-04 0.593716433 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 381067 381067 'Zfp229' mRNA 169 159 223 1.87 1.79 2.69 1.25 1.22 1.01 2.116666667 1.16 130 118 102 183.6666667 116.6666667 0.004592343 -0.67574683 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 381072 381072 'Abca17' mRNA 0 2 1 0 0.03 0.01 0.02 0.01 0.04 0.013333333 0.023333333 2 1 4 1 2.333333333 0.624717354 1.213737597 02010///ABC transporters GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006629///lipid metabolic process+++GO:0006638///neutral lipid metabolic process+++GO:0006869///lipid transport+++GO:0055085///transmembrane transport 381073 381073 'Npw' mRNA 2 0 2 0.19 0 0.2 0.75 0.43 0.69 0.13 0.623333333 9 5 8 1.333333333 7.333333333 0.088734267 2.431141095 04080///Neuroactive ligand-receptor interaction GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0001664///G protein-coupled receptor binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007631///feeding behavior 381077 381077 'Ccdc78' mRNA 20.87 18.75 14 0.75 0.65 0.52 0.74 1.11 0.62 0.64 0.823333333 24 34 18.91 17.87333333 25.63666667 0.396422657 0.542949595 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm+++GO:0098536///deuterosome GO:0003674///molecular_function GO:0003009///skeletal muscle contraction+++GO:0030030///cell projection organization+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation 381085 381085 'Tbc1d22b' mRNA 495 550 166 7.66 8.39 2.71 2.41 3.64 4.48 6.253333333 3.51 180 265 322 403.6666667 255.6666667 0.317487732 -0.642752627 GO:0005096///GTPase activator activity+++GO:0071889///14-3-3 protein binding GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 381091 381091 'H2-Eb2' mRNA 1 1 0 0.04 0.04 0 0.04 0 0.01 0.026666667 0.016666667 1 0 1 0.666666667 0.666666667 0.998591786 0.007987197 04145///Phagosome+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04640///Hematopoietic cell lineage+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04672///Intestinal immune network for IgA production+++04940///Type I diabetes mellitus+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05310///Asthma+++05320///Autoimmune thyroid disease+++05321///Inflammatory bowel disease+++05322///Systemic lupus erythematosus+++05323///Rheumatoid arthritis+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0001772///immunological synapse+++GO:0005765///lysosomal membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0042613///MHC class II protein complex GO:0023026///MHC class II protein complex binding+++GO:0030247///polysaccharide binding+++GO:0032395///MHC class II receptor activity+++GO:0042605///peptide antigen binding+++GO:0042608///T cell receptor binding+++GO:0042609///CD4 receptor binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050870///positive regulation of T cell activation 381101 381101 'Dnph1' mRNA 244 248.3 243 13.78 13.86 14.56 13.24 14.09 13.34 14.06666667 13.55666667 269 279 262 245.1 270 0.50189098 0.128479507 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity" GO:0000255///allantoin metabolic process+++GO:0008152///metabolic process+++GO:0009116///nucleoside metabolic process+++GO:0009117///nucleotide metabolic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0030307///positive regulation of cell growth+++GO:0030855///epithelial cell differentiation+++GO:0046055///dGMP catabolic process 381104 381104 'Prickle4' mRNA 101 92 73 4.26 3.82 3.28 0.44 0.64 1 3.786666667 0.693333333 12 17 27 88.66666667 18.66666667 4.36E-09 -2.252143068 04310///Wnt signaling pathway GO:0001725///stress fiber+++GO:0005912///adherens junction+++GO:0030018///Z disc+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0061061///muscle structure development 381107 381107 'Tmem232' mRNA 46 73 48 0.95 1.63 1.09 0.12 0.05 0.12 1.223333333 0.096666667 7 2 6 55.66666667 5 1.35E-09 -3.486511148 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381110 381110 'Rmdn2' mRNA 408 339 294 11.4 9.15 8.18 5.63 5.13 6.13 9.576666667 5.63 226 198 230 347 218 3.74E-05 -0.679257034 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole GO:0008017///microtubule binding GO:0008150///biological_process 381112 381112 'Arhgef33' mRNA 224 206 166 1.84 1.65 1.4 0.79 0.71 0.88 1.63 0.793333333 118 100 124 198.6666667 114 1.09E-04 -0.809424787 GO:0005575///cellular_component GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 381113 381113 'Cdkl4' mRNA 1628 1686 1663 29.98 30.51 32.53 1.89 2.13 2.38 31.00666667 2.133333333 118 129 144 1659 130.3333333 1.07E-221 -3.682203727 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle 381126 381126 'Garem1' mRNA 509 509 425 5.7 5.6 5.04 3.26 2.68 2.95 5.446666667 2.963333333 335 269 294 481 299.3333333 2.91E-07 -0.694481002 GO:0005575///cellular_component GO:0070064///proline-rich region binding GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0051781///positive regulation of cell division+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus 381142 381142 'Arl14epl' mRNA 0 6 2 0 0.15 0.05 0.08 0.1 0.08 0.066666667 0.086666667 3 4 3 2.666666667 3.333333333 0.863328977 0.325483303 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381148 381148 'Prob1' mRNA 706 755 696 7.75 8.14 8.1 5.16 5.25 5.21 7.996666667 5.206666667 542 538 530 719 536.6666667 4.26E-05 -0.43314601 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 381157 381157 'Greb1l' mRNA 328 351 278 2.08 2.34 1.94 1.66 1.76 2 2.12 1.806666667 294 300 329 319 307.6666667 0.765959094 -0.059812008 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001656///metanephros development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0003231///cardiac ventricle development+++GO:0007275///multicellular organism development+++GO:0030539///male genitalia development+++GO:0060065///uterus development+++GO:0060562///epithelial tube morphogenesis+++GO:0061205///paramesonephric duct development+++GO:0072177///mesonephric duct development 381175 381175 'Ccdc68' mRNA 1298 1378 1284 47.5 49.57 49.85 8.93 9.58 10.46 48.97333333 9.656666667 273 293 319 1320 295 3.97E-98 -2.172532031 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0120103///centriolar subdistal appendage GO:0003674///molecular_function GO:0008104///protein localization+++GO:0034454///microtubule anchoring at centrosome+++GO:0035556///intracellular signal transduction 381196 381196 'Gm960' mRNA 12 17 14 0.29 0.41 0.36 0.29 0.13 0.07 0.353333333 0.163333333 14 6 3 14.33333333 7.666666667 0.308544668 -0.922353106 GO:0005575///cellular_component+++GO:0005694///chromosome GO:0003918///DNA topoisomerase type II (ATP-hydrolyzing) activity+++GO:0005515///protein binding GO:0007131///reciprocal meiotic recombination+++GO:0042138///meiotic DNA double-strand break formation+++GO:0051321///meiotic cell cycle 381199 381199 'Tmem151a' mRNA 37 55 52 0.5 0.74 0.75 0.39 0.33 0.55 0.663333333 0.423333333 33 27 45 48 35 0.308898887 -0.470105833 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381201 381201 'Ap5b1' mRNA 218 194 187 4.32 3.79 3.91 7.33 7.61 7.69 4.006666667 7.543333333 428 439 437 199.6666667 434.6666667 6.58E-15 1.111988218 GO:0030119///AP-type membrane coat adaptor complex GO:0003674///molecular_function GO:0015031///protein transport+++GO:0016197///endosomal transport 381203 381203 'Slc22a20' mRNA 3 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 1 0 0.653555534 -2.427804616 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0055085///transmembrane transport 381204 381204 'Naaladl1' mRNA 3.02 6.01 5.07 0.06 0.12 0.11 0.09 0.04 0.11 0.096666667 0.08 5 2 6 4.7 4.333333333 0.93598557 -0.123618886 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0004177///aminopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0043171///peptide catabolic process 381213 381213 'Ms4a12' mRNA 35.35 32.26 20.34 1.09 0.98 0.66 0.68 0.3 0.45 0.91 0.476666667 25.39 11.01 16.16 29.31666667 17.52 0.212594527 -0.75103675 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381217 381217 'Fam189a2' mRNA 222 190 184 4.83 4.08 4.26 4.4 4 4.55 4.39 4.316666667 232 206 232 198.6666667 223.3333333 0.455216202 0.157663106 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381218 381218 '4430402I18Rik' mRNA 328.06 308.29 332.96 7.99 7.24 8.36 0.94 0.89 1.05 7.863333333 0.96 44.89 45.16 45.75 323.1033333 45.26666667 3.04E-43 -2.866445029 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097224///sperm connecting piece GO:0003674///molecular_function+++GO:0032027///myosin light chain binding GO:0007283///spermatogenesis+++GO:0008150///biological_process 381229 381229 'Cfap58' mRNA 86 84 82 1.4 1.35 1.42 0.09 0.17 0.15 1.39 0.136666667 6 12 10 84 9.333333333 1.23E-13 -3.179164822 GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097225///sperm midpiece GO:0003674///molecular_function GO:0007288///sperm axoneme assembly+++GO:0030317///flagellated sperm motility 381236 381236 'Lipo3' mRNA 365.88 383.49 361.18 6.9 7.1 7.19 6.75 6.56 6.62 7.063333333 6.643333333 397.03 381.44 390.46 370.1833333 389.6433333 0.720642128 0.063104599 GO:0043231///intracellular membrane-bounded organelle "GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds" GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process 381259 381259 'Tmem237' mRNA 537 606 585 16.77 18.62 19.34 16.15 18.03 15.74 18.24333333 16.64 594 648 560 576 600.6666667 0.765715423 0.048540852 GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection GO:0005515///protein binding GO:0030030///cell projection organization+++GO:0030111///regulation of Wnt signaling pathway+++GO:0060271///cilium assembly 381260 381260 'Gm973' mRNA 345.46 332.27 268.31 4.1 3.91 3.43 6.42 5.44 6.19 3.813333333 6.016666667 588.59 500.01 531.61 315.3466667 540.07 4.22E-09 0.767516084 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381269 381269 'Mreg' mRNA 1228 1255 725 27.24 27.17 16.77 2.98 3.15 4.1 23.72666667 3.41 158 164 204 1069.333333 175.3333333 3.08E-55 -2.607887346 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031300///intrinsic component of organelle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex+++GO:0033162///melanosome membrane+++GO:0042470///melanosome GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding GO:0030318///melanocyte differentiation+++GO:0032400///melanosome localization+++GO:0032402///melanosome transport+++GO:0042640///anagen+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0072385///minus-end-directed organelle transport along microtubule+++GO:0090382///phagosome maturation 381270 381270 'Marchf4' mRNA 132 124 81 1.59 1.36 1.11 0.09 0.08 0.12 1.353333333 0.096666667 9 7 10 112.3333333 8.666666667 5.98E-19 -3.699753951 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination 381280 381280 'Hjurp' mRNA 673.29 741.84 680.76 7.9 8.54 8.6 8.99 8.21 9.52 8.346666667 8.906666667 857.84 777.2 882.98 698.63 839.34 0.017413472 0.253066186 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005739///mitochondrion" GO:0003677///DNA binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0043254///regulation of protein complex assembly+++GO:0051101///regulation of DNA binding 381284 381284 'Crocc2' mRNA 31 27 48 0.22 0.2 0.37 1.57 1.72 1.71 0.263333333 1.666666667 248 264 255 35.33333333 255.6666667 7.72E-30 2.836795636 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381287 381287 'A530032D15Rik' mRNA 6.31 5.2 7.4 0.34 0.17 0.34 1.53 1.78 1.73 0.283333333 1.68 43.09 50.8 45.67 6.303333333 46.52 1.52E-07 2.925528485 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 381290 381290 'Atp2b4' mRNA 288 252 234 1.82 1.59 1.58 1.84 1.67 1.98 1.663333333 1.83 338 297 351 258 328.6666667 0.0374749 0.338724267 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04925///Aldosterone synthesis and secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04972///Pancreatic secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0031514///motile cilium+++GO:0032991///protein-containing complex+++GO:0036126///sperm flagellum+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097228///sperm principal piece+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0017080///sodium channel regulator activity+++GO:0019829///cation-transporting ATPase activity+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0030346///protein phosphatase 2B binding+++GO:0036487///nitric-oxide synthase inhibitor activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050998///nitric-oxide synthase binding+++GO:0097110///scaffold protein binding GO:0003407///neural retina development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007283///spermatogenesis+++GO:0010629///negative regulation of gene expression+++GO:0010751///negative regulation of nitric oxide mediated signal transduction+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0016525///negative regulation of angiogenesis+++GO:0021766///hippocampus development+++GO:0030317///flagellated sperm motility+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051599///response to hydrostatic pressure+++GO:0070588///calcium ion transmembrane transport+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071872///cellular response to epinephrine stimulus+++GO:0098736///negative regulation of the force of heart contraction+++GO:0140199///negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:1900082///negative regulation of arginine catabolic process+++GO:1901660///calcium ion export+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1902305///regulation of sodium ion transmembrane transport+++GO:1902548///negative regulation of cellular response to vascular endothelial growth factor stimulus+++GO:1902806///regulation of cell cycle G1/S phase transition+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress+++GO:1903249///negative regulation of citrulline biosynthetic process+++GO:1905145///cellular response to acetylcholine+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity 381293 381293 'Kif14' mRNA 1 7 5 0.01 0.05 0.03 0.36 0.22 0.37 0.03 0.316666667 65 36 58 4.333333333 53 6.03E-09 3.596217898 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0090543///Flemming body "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0015631///tubulin binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0001558///regulation of cell growth+++GO:0007018///microtubule-based movement+++GO:0007019///microtubule depolymerization+++GO:0007080///mitotic metaphase plate congression+++GO:0008284///positive regulation of cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0021685///cerebellar granular layer structural organization+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0021695///cerebellar cortex development+++GO:0021766///hippocampus development+++GO:0021772///olfactory bulb development+++GO:0021846///cell proliferation in forebrain+++GO:0021987///cerebral cortex development+++GO:0030155///regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031641///regulation of myelination+++GO:0032147///activation of protein kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0032487///regulation of Rap protein signal transduction+++GO:0033624///negative regulation of integrin activation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045184///establishment of protein localization+++GO:0051301///cell division+++GO:1903429///regulation of cell maturation+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 381305 381305 'Rc3h1' mRNA 902 931 738 4.28 4.34 3.71 3.19 2.98 3.11 4.11 3.093333333 774 706 731 857 737 0.035291779 -0.225996773 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0035198///miRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1905762///CCR4-NOT complex binding "GO:0000209///protein polyubiquitination+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0001782///B cell homeostasis+++GO:0002634///regulation of germinal center formation+++GO:0002635///negative regulation of germinal center formation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010468///regulation of gene expression+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0030889///negative regulation of B cell proliferation+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0042098///T cell proliferation+++GO:0042129///regulation of T cell proliferation+++GO:0043029///T cell homeostasis+++GO:0043488///regulation of mRNA stability+++GO:0045623///negative regulation of T-helper cell differentiation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0050852///T cell receptor signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050863///regulation of T cell activation+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0061470///T follicular helper cell differentiation+++GO:0071347///cellular response to interleukin-1+++GO:1900151///regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000628///regulation of miRNA metabolic process" 381306 381306 'BC055324' mRNA 51.75 71.09 42.85 0.85 1.2 0.82 1.07 1.3 1.17 0.956666667 1.18 69.75 81.35 71.52 55.23 74.20666667 0.236684375 0.427300676 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381308 381308 'Ifi211' mRNA 52.71 36.31 24.25 1.78 1.15 0.83 21.44 21.78 23.15 1.253333333 22.12333333 757.54 747.9 780.71 37.75666667 762.05 3.60E-118 4.342605425 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0034399///nuclear periphery+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009617///response to bacterium+++GO:0030889///negative regulation of B cell proliferation+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035458///cellular response to interferon-beta+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway 381310 381310 'Stum' mRNA 71 70 58 0.56 0.55 0.49 0.08 0.08 0.14 0.533333333 0.1 12 12 20 66.33333333 14.66666667 2.05E-07 -2.184730978 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381314 381314 'Iars2' mRNA 1308.26 1362.04 1040.3 18.51 19.06 15.29 13.3 15.38 15.07 17.62 14.58333333 1066.37 1196.18 1173.37 1236.866667 1145.306667 0.31519719 -0.116634517 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004822///isoleucine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006428///isoleucyl-tRNA aminoacylation+++GO:0032543///mitochondrial translation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 381318 381318 'Nsl1' mRNA 64.67 63 72.4 1.11 1.09 1.39 2.84 2.68 2.67 1.196666667 2.73 161.01 158.22 148.79 66.69 156.0066667 3.56E-07 1.216152893 "GO:0000444///MIS12/MIND type complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0016607///nuclear speck" GO:0003674///molecular_function GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051301///cell division 381319 381319 'Batf3' mRNA 44 24 35 4.39 2.38 3.7 5.41 6.45 5.69 3.49 5.85 62 72 63 34.33333333 65.66666667 0.0164388 0.922626756 05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009615///response to virus+++GO:0030154///cell differentiation+++GO:0043011///myeloid dendritic cell differentiation+++GO:0097028///dendritic cell differentiation" 381334 381334 'Gal3st2' mRNA 19.15 18.91 12.45 0.37 0.36 0.26 0.67 0.67 0.69 0.33 0.676666667 40.03 39.1 39.57 16.83666667 39.56666667 0.009734389 1.262374032 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process+++GO:0051923///sulfation 381337 381337 'Fam178b' mRNA 1481 1395 1317 106.55 100.4 100.55 52.31 57.8 52.28 102.5 54.13 847 907 813 1397.666667 855.6666667 3.72E-16 -0.718095751 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381338 381338 'Lonrf2' mRNA 173 190 162 1.33 1.43 1.32 0.81 0.76 0.89 1.36 0.82 122 112 130 175 121.3333333 0.010807953 -0.538448257 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 381339 381339 'Tmem182' mRNA 2 2 0 0.05 0.06 0 0.06 0 0.06 0.036666667 0.04 3 0 3 1.333333333 2 0.840843897 0.591824357 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381350 381350 'Spag6' mRNA 0 1 3 0 0.02 0.08 0 0.04 0 0.033333333 0.013333333 0 2 0 1.333333333 0.666666667 0.778014436 -1.033112359 GO:0001669///acrosomal vesicle+++GO:0002177///manchette+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece+++GO:1990716///axonemal central apparatus GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0008017///microtubule binding "GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0006931///substrate-dependent cell migration, cell attachment to substrate+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0008150///biological_process+++GO:0010761///fibroblast migration+++GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0034613///cellular protein localization+++GO:0043149///stress fiber assembly+++GO:0043583///ear development+++GO:0044458///motile cilium assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0046847///filopodium assembly+++GO:0051301///cell division+++GO:0090175///regulation of establishment of planar polarity+++GO:0090660///cerebrospinal fluid circulation+++GO:1905515///non-motile cilium assembly+++GO:1990138///neuron projection extension" 381352 381352 'Mamdc4' mRNA 33 28 39 0.45 0.37 0.56 0.25 0.29 0.25 0.46 0.263333333 21 24 21 33.33333333 22 0.242440592 -0.616692407 GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0015031///protein transport 381353 381353 'Ajm1' mRNA 71 48 54 0.81 0.54 0.66 0.34 0.35 0.27 0.67 0.32 34 34 26 57.66666667 31.33333333 0.025355054 -0.891916429 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043296///apical junction complex GO:0003674///molecular_function GO:0045216///cell-cell junction organization 381356 381356 'Cacfd1' mRNA 3279 3239 3329 87.32 84.6 94.44 43.79 43.91 41.45 88.78666667 43.05 1872 1813 1673 3282.333333 1786 1.51E-34 -0.891608944 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0016192///vesicle-mediated transport 381359 381359 'Prdm12' mRNA 182 176 61 3.12 2.96 0.72 0.08 0.32 0.36 2.266666667 0.253333333 4 19 22 139.6666667 15 7.32E-05 -3.198785806 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:1990226///histone methyltransferase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0019233///sensory perception of pain+++GO:0022008///neurogenesis+++GO:0031175///neuron projection development+++GO:0032259///methylation+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:1900111///positive regulation of histone H3-K9 dimethylation 381373 381373 'Sp9' mRNA 0 2 2 0 0.04 0.04 0 0 0.05 0.026666667 0.016666667 0 0 3 1.333333333 1 0.893171008 -0.433714176 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030326///embryonic limb morphogenesis 381375 381375 'Pjvk' mRNA 1757 1840 1801 90.17 95.5 99.17 10.39 9.23 9.14 94.94666667 9.586666667 237 184 185 1799.333333 202 7.62E-192 -3.169186388 GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0035253///ciliary rootlet+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0120044///stereocilium base GO:0005515///protein binding GO:0000302///response to reactive oxygen species+++GO:0000425///pexophagy+++GO:0007605///sensory perception of sound+++GO:0008219///cell death+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0097468///programmed cell death in response to reactive oxygen species+++GO:0120045///stereocilium maintenance+++GO:1900063///regulation of peroxisome organization 381379 381379 'Med19' mRNA 951.99 989.38 868.12 26.24 26.87 25.39 21.99 23.29 21.43 26.16666667 22.23666667 917.1 948.47 865.35 936.4966667 910.3066667 0.683019115 -0.050318371 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 381390 381390 'Gm14147' mRNA 6.21 11.46 7.82 0.09 0.17 0.12 0.04 0.02 0 0.126666667 0.02 3 1.32 0 8.496666667 1.44 0.063297882 -2.600376723 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0008150///biological_process+++GO:0035556///intracellular signal transduction 381393 381393 '4921509C19Rik' mRNA 2.79 6.54 5.18 0.05 0.11 0.09 0 0.04 0.04 0.083333333 0.026666667 0 2.68 2 4.836666667 1.56 0.341749758 -1.705235908 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 381399 381399 'Bpifb4' mRNA 67 46 62 1.79 1.21 1.76 0.7 0.72 1.03 1.586666667 0.816666667 30 30 43 58.33333333 34.33333333 0.053678354 -0.779492214 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0008289///lipid binding GO:0008150///biological_process 381404 381404 'Pabpc1l' mRNA 10 2 13 0.27 0.05 0.38 0.19 0.37 0.2 0.233333333 0.253333333 8 16 8 8.333333333 10.66666667 0.782367455 0.329372245 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding "GO:0001556///oocyte maturation+++GO:0006338///chromatin remodeling+++GO:0006378///mRNA polyadenylation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0051647///nucleus localization" 381406 381406 'Trp53rka' mRNA 646.69 628.1 648.69 19.86 19.01 21.14 16.19 19.59 18.68 20.00333333 18.15333333 605.91 715.47 676.51 641.16 665.9633333 0.79013349 0.043136466 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0008033///tRNA processing+++GO:0016310///phosphorylation+++GO:0070525///tRNA threonylcarbamoyladenosine metabolic process 381409 381409 'Cdh26' mRNA 10 8 1 0.19 0.16 0.03 0 0.09 0.05 0.126666667 0.046666667 0 4 3 6.333333333 2.333333333 0.373072341 -1.412068921 GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0008013///beta-catenin binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0070097///delta-catenin binding "GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0035710///CD4-positive, alpha-beta T cell activation+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules" 381410 381410 'Zfp408' mRNA 234.01 235.83 206.58 2.49 2.66 2.37 2.01 1.7 1.81 2.506666667 1.84 215.37 177.92 177 225.4733333 190.0966667 0.187934654 -0.257760527 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding GO:0006357///regulation of transcription by RNA polymerase II 381411 381411 'Accsl' mRNA 3 4 3 0.08 0.1 0.08 0.09 0 0 0.086666667 0.03 4 0 0 3.333333333 1.333333333 0.536867369 -1.353088703 GO:0005575///cellular_component GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0030170///pyridoxal phosphate binding GO:0006520///cellular amino acid metabolic process+++GO:0008150///biological_process+++GO:0009058///biosynthetic process 381413 381413 'Gpr176' mRNA 91 66 68 1.07 0.87 0.9 1.35 1.72 1.24 0.946666667 1.436666667 114 145 104 75 121 0.015651774 0.68150986 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0048512///circadian behavior 381417 381417 'Slc28a2b' mRNA 1.3 1.07 3.61 0.02 0.02 0.06 0.8 0.75 0.57 0.033333333 0.706666667 63.5 56.2 42.94 1.993333333 54.21333333 3.77E-10 4.990998579 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030135///coated vesicle GO:0005326///neurotransmitter transporter activity+++GO:0005337///nucleoside transmembrane transporter activity+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0015211///purine nucleoside transmembrane transporter activity+++GO:0015213///uridine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015389///pyrimidine- and adenine-specific:sodium symporter activity GO:0001895///retina homeostasis+++GO:0006836///neurotransmitter transport+++GO:0015855///pyrimidine nucleobase transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0015862///uridine transport+++GO:0032238///adenosine transport+++GO:0034394///protein localization to cell surface+++GO:0035340///inosine transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1901642///nucleoside transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport 381418 381418 'Ctxn2' mRNA 5 5 3 0.78 0.78 0.5 0.14 0 0 0.686666667 0.046666667 1 0 0 4.333333333 0.333333333 0.082069645 -3.598238172 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381438 381438 'Gm5148' mRNA 147.83 129.17 89.62 7.45 6.43 4.79 3.72 3.2 5.29 6.223333333 4.07 84.68 71.1 116.38 122.2066667 90.72 0.155807298 -0.433621787 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381457 381457 'Crnn' mRNA 0 2 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0046914///transition metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0009408///response to heat+++GO:0010468///regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071345///cellular response to cytokine stimulus+++GO:0098609///cell-cell adhesion+++GO:1902808///positive regulation of cell cycle G1/S phase transition 381463 381463 'Nr1h5' mRNA 5.99 10 3 0.12 0.19 0.07 0.04 0.07 0.04 0.126666667 0.05 1.97 3.99 2.15 6.33 2.703333333 0.280485607 -1.57228283 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0032052///bile acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006629///lipid metabolic process+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0038183///bile acid signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II" 381476 381476 'Stpg2' mRNA 5 3 5 0.11 0.06 0.11 0 0.02 0.08 0.093333333 0.033333333 0 1 4 4.333333333 1.666666667 0.438626142 -1.39013963 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381484 381484 'Gm5150' mRNA 4 5 1 0.29 0.4 0.08 5.16 6.02 5.93 0.256666667 5.703333333 92 104 85 3.333333333 93.66666667 3.51E-17 4.807853848 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation 381485 381485 'Trim55' mRNA 28 27 20 0.79 0.63 0.45 0.11 0.11 0.03 0.623333333 0.083333333 5 4 1 25 3.333333333 1.89E-04 -2.915112699 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0002522///leukocyte migration involved in immune response+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0010934///macrophage cytokine production+++GO:0016567///protein ubiquitination+++GO:0032635///interleukin-6 production+++GO:0050904///diapedesis+++GO:1905517///macrophage migration 381493 381493 'S100a7a' mRNA 20.42 14.92 19.88 0.83 0.53 0.68 0.32 0.67 0.42 0.68 0.47 7.5 18.2 12.16 18.40666667 12.62 0.510191572 -0.527677513 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042056///chemoattractant activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0050786///RAGE receptor binding GO:0001816///cytokine production+++GO:0006954///inflammatory response+++GO:0050918///positive chemotaxis 381510 381510 'Dpy19l4' mRNA 528 552 468 4.13 4.25 3.89 3.83 3.6 4.04 4.09 3.823333333 563 518 575 516 552 0.537276032 0.087582897 GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000030///mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan 381511 381511 'Pdp1' mRNA 338 348 286 4.33 4.39 3.89 4.44 4.8 4.6 4.203333333 4.613333333 399 420 399 324 406 0.026027735 0.317324941 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004741///[pyruvate dehydrogenase (lipoamide)] phosphatase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:1904184///positive regulation of pyruvate dehydrogenase activity 381522 381522 'Ccdc180' mRNA 0 1 2 0 0.01 0.02 0.02 0.1 0.06 0.01 0.06 2 11 6 1 6.333333333 0.105895923 2.646168118 GO:0003674///molecular_function GO:0008150///biological_process 381534 381534 'Ube2u' mRNA 119 136 115 4.63 5.22 4.74 0.78 0.87 0.73 4.863333333 0.793333333 23 25 21 123.3333333 23 4.16E-15 -2.43240858 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 381538 381538 'Mroh7' mRNA 328 380 254 4.32 4.94 3.55 0.38 0.46 0.52 4.27 0.453333333 33 39 44 320.6666667 38.66666667 6.08E-41 -3.055601786 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381544 381544 'Armh1' mRNA 228 285 248 7.13 8.76 8.15 5.46 5.67 7.24 8.013333333 6.123333333 204 205 258 253.6666667 222.3333333 0.334645614 -0.200633424 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381546 381546 'Ccdc24' mRNA 118.68 129.06 145.94 5.25 5.6 6.55 1.18 1.9 1.88 5.8 1.653333333 29 48.88 44 131.2266667 40.62666667 7.95E-09 -1.7086172 GO:0005575///cellular_component GO:0003674///molecular_function GO:0001835///blastocyst hatching 381549 381549 'Zfp69' mRNA 167 162 167 3.91 3.77 4.2 1.74 1.97 2.16 3.96 1.956666667 85 94 101 165.3333333 93.33333333 1.76E-04 -0.83678036 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0019216///regulation of lipid metabolic process" 381560 381560 'Xkr8' mRNA 150.16 122.48 143.05 1.91 1.53 1.95 1.91 1.89 1.84 1.796666667 1.88 173 166.92 161 138.5633333 166.9733333 0.279846102 0.254636605 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017128///phospholipid scramblase activity GO:0002513///tolerance induction to self antigen+++GO:0006915///apoptotic process+++GO:0043652///engulfment of apoptotic cell+++GO:0045663///positive regulation of myoblast differentiation+++GO:0051649///establishment of localization in cell+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:0097350///neutrophil clearance+++GO:1902742///apoptotic process involved in development 381580 381580 'Ccdc27' mRNA 1 1 2 0.03 0.03 0.05 0.02 0.07 0 0.036666667 0.03 1 3 0 1.333333333 1.333333333 0.998591786 -0.018640253 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381582 381582 'Tmem240' mRNA 86 56 53 2.63 1.79 1.84 0.61 0.94 0.73 2.086666667 0.76 26 32 28 65 28.66666667 0.002324977 -1.18730051 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0097060///synaptic membrane GO:0003674///molecular_function GO:0008150///biological_process 381591 381591 'L1td1' mRNA 3 1 2 0.06 0.02 0.04 0.05 0.08 0.13 0.04 0.086666667 3 5 8 2 5.333333333 0.35448814 1.405591615 GO:0043231///intracellular membrane-bounded organelle+++GO:1990904///ribonucleoprotein complex GO:0003727///single-stranded RNA binding "GO:0032197///transposition, RNA-mediated" 381605 381605 'Tbc1d2' mRNA 126 134 101 1.56 1.66 1.32 1.8 1.33 1.31 1.513333333 1.48 151 120 118 120.3333333 129.6666667 0.749855753 0.09854416 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity+++GO:0045296///cadherin binding GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity 381622 381622 '5031410I06Rik' mRNA 145.69 149.96 181.61 2.72 2.75 3.6 0.05 0.09 0.04 3.023333333 0.06 3.2 5.6 2.21 159.0866667 3.67 1.07E-25 -5.587095181 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381626 381626 'Rbm33' mRNA 610 595 555 3.35 3.22 3.24 2.56 2.26 2.27 3.27 2.363333333 537 461 460 586.6666667 486 0.019136422 -0.283600946 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding GO:0008150///biological_process 381628 381628 'Adgrf3' mRNA 2 0 0 0.04 0 0 0 0 0.04 0.013333333 0.013333333 0 0 2 0.666666667 0.666666667 0.998591786 0.017925808 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway 381629 381629 'Atraid' mRNA 3205 3273 3129 213.54 215.61 221.02 192.84 202.56 187.39 216.7233333 194.2633333 3321 3403 3121 3202.333333 3281.666667 0.797310085 0.023791592 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:1903363///negative regulation of cellular protein catabolic process 381633 381633 'Gm1673' mRNA 246 233 287 37.37 35.39 47.06 39.12 41.46 44.83 39.94 41.80333333 287 298 310 255.3333333 298.3333333 0.27361338 0.208580149 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 381634 381634 'Gm1043' mRNA 1066 1058 792 5.83 5.64 4.59 0.4 0.31 0.42 5.353333333 0.376666667 84 63 87 972 78 4.07E-123 -3.646287857 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381644 381644 'Cep135' mRNA 134 168 155 1.37 1.6 1.6 1.97 1.73 2.27 1.523333333 1.99 211 180 244 152.3333333 211.6666667 0.029281535 0.461684078 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0008022///protein C-terminus binding GO:0007099///centriole replication+++GO:0010457///centriole-centriole cohesion+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:1904951///positive regulation of establishment of protein localization 381651 381651 'Odaph' mRNA 1 4 2 0.09 0.36 0.19 0.88 0.74 1.24 0.213333333 0.953333333 11 9 15 2.333333333 11.66666667 0.031637878 2.314987872 GO:0005575///cellular_component GO:0003674///molecular_function GO:0070169///positive regulation of biomineral tissue development+++GO:0070175///positive regulation of enamel mineralization 381667 381667 'Lrcol1' mRNA 0 0 1 0 0 0.09 0.35 0.07 0.07 0.03 0.163333333 5 1 1 0.333333333 2.333333333 0.324442947 2.674973297 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0008047///enzyme activator activity GO:0007586///digestion+++GO:0016042///lipid catabolic process+++GO:0032094///response to food+++GO:0050790///regulation of catalytic activity 381668 381668 'Fbrsl1' mRNA 596 512 278 8.67 7.17 4.49 4.11 6.14 5.75 6.776666667 5.333333333 315 475 434 462 408 0.72761441 -0.17248549 GO:0005575///cellular_component GO:0008150///biological_process 381677 381677 'Vgf' mRNA 1 0 0 0.02 0 0 0.04 0.08 0.04 0.006666667 0.053333333 2 4 2 0.333333333 2.666666667 0.246130284 2.889958876 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0008083///growth factor activity GO:0001541///ovarian follicle development+++GO:0002021///response to dietary excess+++GO:0006091///generation of precursor metabolites and energy+++GO:0007165///signal transduction+++GO:0009409///response to cold+++GO:0019953///sexual reproduction+++GO:0030073///insulin secretion+++GO:0032868///response to insulin+++GO:0033500///carbohydrate homeostasis+++GO:0042593///glucose homeostasis+++GO:0042742///defense response to bacterium+++GO:0043084///penile erection+++GO:0048167///regulation of synaptic plasticity+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0051591///response to cAMP 381678 381678 'Zcwpw1' mRNA 96.71 102.53 120.09 2.23 2.23 2.8 2.2 1.8 1.96 2.42 1.986666667 108.59 93.07 91.89 106.4433333 97.85 0.671600058 -0.140667074 GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding GO:0007127///meiosis I+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045911///positive regulation of DNA recombination+++GO:2000781///positive regulation of double-strand break repair 381680 381680 'Nxpe5' mRNA 23 33 25 0.55 0.76 0.6 13.69 11.15 11.31 0.636666667 12.05 640 519 516 27 558.3333333 3.25E-90 4.358027575 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381693 381693 'Wdr95' mRNA 93 113 134 2.07 2.48 3.19 0.27 0.3 0.36 2.58 0.31 14 16 18 113.3333333 16 2.83E-15 -2.842055119 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381694 381694 'B3glct' mRNA 353 412 258 4.19 4.85 3.26 3.38 3.46 3.53 4.1 3.456666667 328 328 333 341 329.6666667 0.81918928 -0.052348333 00514///Other types of O-glycan biosynthesis GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0005975///carbohydrate metabolic process+++GO:0006004///fucose metabolic process+++GO:0006486///protein glycosylation+++GO:0008150///biological_process 381695 381695 'N4bp2l2' mRNA 1420.76 1479.36 1435.09 8.21 8.5 8.77 7.16 6.83 7.02 8.493333333 7.003333333 1502.78 1373.76 1403.46 1445.07 1426.666667 0.771162392 -0.031599058 GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001824///blastocyst development+++GO:1902035///positive regulation of hematopoietic stem cell proliferation+++GO:1902037///negative regulation of hematopoietic stem cell differentiation 381714 381714 'Gm9758' mRNA 0 1.15 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.383333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381716 381716 'Pttg1ip2' mRNA 5 9 8 0.5 0.89 0.85 0.18 0.18 0 0.746666667 0.12 2 2 0 7.333333333 1.333333333 0.081900862 -2.47526625 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006606///protein import into nucleus 381738 381738 'Drc1' mRNA 1619 1696 1595 36.94 38.29 38.52 3.2 3.19 3.37 37.91666667 3.253333333 161 155 161 1636.666667 159 5.79E-222 -3.375410508 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003352///regulation of cilium movement+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0060285///cilium-dependent cell motility+++GO:0070286///axonemal dynein complex assembly 381741 381741 'Lrrc43' mRNA 596 604 549 16.93 17.17 16.68 0.86 1.1 1.39 16.92666667 1.116666667 33 44 52 583 43 1.16E-91 -3.770480347 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381759 381759 'Wee2' mRNA 141 165 155 2.71 3.13 3.14 0.46 0.21 0.32 2.993333333 0.33 28 12 18 153.6666667 19.33333333 6.31E-21 -3.006992529 04110///Cell cycle+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0007143///female meiotic nuclear division+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035038///female pronucleus assembly+++GO:0042327///positive regulation of phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0051321///meiotic cell cycle+++GO:0060631///regulation of meiosis I+++GO:0080154///regulation of fertilization+++GO:1900194///negative regulation of oocyte maturation 381760 381760 'Ssbp1' mRNA 1115 1150 1190 36.1 38.44 42.73 39.3 39.16 37.07 39.09 38.51 1246 1227 1140 1151.666667 1204.333333 0.674676831 0.050767653 03030///DNA replication+++03430///Mismatch repair+++03440///Homologous recombination GO:0005739///mitochondrion+++GO:0009295///nucleoid+++GO:0042645///mitochondrial nucleoid GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006260///DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0051096///positive regulation of helicase activity+++GO:0051289///protein homotetramerization+++GO:0070584///mitochondrion morphogenesis+++GO:0090297///positive regulation of mitochondrial DNA replication+++GO:1905776///positive regulation of DNA helicase activity 381785 381785 'Gm1070' mRNA 3 0 1 0.06 0 0.02 0.03 0.09 0.1 0.026666667 0.073333333 2 5 6 1.333333333 4.333333333 0.352396081 1.696809581 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381798 381798 '4930590J08Rik' mRNA 68 58 49 0.48 0.39 0.36 0.28 0.15 0.2 0.41 0.21 47 25 33 58.33333333 35 0.064524312 -0.74929165 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 381801 381801 'Tatdn2' mRNA 7 8 13 0.12 0.13 0.23 0.26 0.12 0.36 0.16 0.246666667 18 8 24 9.333333333 16.66666667 0.335398495 0.809819832 GO:0005575///cellular_component "GO:0003674///molecular_function+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters" GO:0008150///biological_process 381802 381802 'Tsen2' mRNA 363 413 412 11.63 13.04 14.03 7.42 8.5 7.52 12.9 7.813333333 266 298 261 396 275 3.86E-04 -0.538663097 GO:0000214///tRNA-intron endonuclease complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0000213///tRNA-intron endonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0016829///lyase activity "GO:0000379///tRNA-type intron splice site recognition and cleavage+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 381810 381810 'Lpar5' mRNA 13 20 9 0.24 0.3 0.18 2.05 2.03 2.38 0.24 2.153333333 139 132 153 14 141.3333333 4.82E-22 3.330255644 04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0048266///behavioral response to pain 381812 381812 'Cracr2a' mRNA 35.3 55.41 31.69 0.24 0.41 0.23 0.59 0.54 0.59 0.293333333 0.573333333 78.35 75.74 84.31 40.8 79.46666667 0.005233654 0.96543576 GO:0000139///Golgi membrane+++GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0033093///Weibel-Palade body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0002115///store-operated calcium entry+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0016197///endosomal transport+++GO:0032237///activation of store-operated calcium channel activity+++GO:0034776///response to histamine+++GO:0045063///T-helper 1 cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0051928///positive regulation of calcium ion transport 381813 381813 'Prmt8' mRNA 7 14 20 0.16 0.31 0.49 0.02 0.04 0.1 0.32 0.053333333 1 2 5 13.66666667 2.666666667 0.021539788 -2.380791261 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098753///anchored component of the cytoplasmic side of the plasma membrane GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0035241///protein-arginine omega-N monomethyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:1904047///S-adenosyl-L-methionine binding "GO:0006479///protein methylation+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0032259///methylation+++GO:0034969///histone arginine methylation+++GO:0051260///protein homooligomerization" 381820 381820 'Smim10l1' mRNA 2535 2738 2528 56.35 60.52 60.21 52.42 51.97 51.89 59.02666667 52.09333333 2704 2543 2561 2600.333333 2602.666667 0.903243001 -0.010509294 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381823 381823 'Apold1' mRNA 237 250 256 3.94 4.09 4.51 3.54 3.62 3.48 4.18 3.546666667 245 245 233 247.6666667 241 0.819258956 -0.052601196 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008289///lipid binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006869///lipid transport+++GO:0042118///endothelial cell activation+++GO:0042157///lipoprotein metabolic process+++GO:0045601///regulation of endothelial cell differentiation 381833 381833 'Prb1' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04970///Salivary secretion GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381835 381835 'Sbk3' mRNA 67 73 66 0.71 0.79 0.74 0.18 0.26 0.3 0.746666667 0.246666667 20 28 32 68.66666667 26.66666667 2.43E-04 -1.373035879 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 381836 381836 'Sbk2' mRNA 35 10 24 1.04 0.29 0.77 0.85 0.89 0.99 0.7 0.91 37 35 37 23 36.33333333 0.264968587 0.642797227 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 381838 381838 'Vmn2r43' mRNA 0 5 3 0 0.1 0.06 0.03 0 0 0.053333333 0.01 2 0 0 2.666666667 0.666666667 0.454284894 -2.032202279 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 381845 381845 'Rnf225' mRNA 76 67 56 1.28 1.11 1 0.92 0.93 1.09 1.13 0.98 63 62 72 66.33333333 65.66666667 0.958851084 -0.022253154 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination 381853 381853 'Gipr' mRNA 29.99 28.33 24.02 0.48 0.35 0.35 0.09 0.16 0.25 0.393333333 0.166666667 9 15.73 23.19 27.44666667 15.97333333 0.202699505 -0.790098495 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0016519///gastric inhibitory peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0038023///signaling receptor activity+++GO:0120022///glucagon binding GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0009749///response to glucose+++GO:0031018///endocrine pancreas development+++GO:0032024///positive regulation of insulin secretion+++GO:0038192///gastric inhibitory peptide signaling pathway+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0048678///response to axon injury+++GO:0051592///response to calcium ion+++GO:0070542///response to fatty acid 381867 381867 'Ovol3' mRNA 2 1 0 0.06 0.03 0 0 0 0 0.03 0 0 0 0 1 0 0.614783931 -2.421998967 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009913///epidermal cell differentiation 381884 381884 'Slc6a16' mRNA 22 22 36 0.38 0.37 0.66 0.13 0.02 0.05 0.47 0.066666667 8 1 3 26.66666667 4 3.65E-04 -2.77111876 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015293///symporter activity GO:0035725///sodium ion transmembrane transport 381903 381903 'Alg8' mRNA 196 176 199 5.57 4.93 6 9.72 11.3 10.27 5.5 10.43 393 446 402 190.3333333 413.6666667 7.77E-13 1.107317609 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0042283///dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0097502///mannosylation 381917 381917 'Dnah3' mRNA 18 19 14 0.07 0.07 0.06 0.06 0.08 0.06 0.066666667 0.066666667 17 23 19 17 19.66666667 0.791143807 0.205624368 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0007018///microtubule-based movement 381921 381921 'Taok2' mRNA 2327 2416 2262 25.32 25.62 25.37 15.45 15.37 14.11 25.43666667 14.97666667 1648 1615 1462 2335 1575 2.63E-15 -0.579710256 04010///MAPK signaling pathway GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0044294///dendritic growth cone+++GO:0044295///axonal growth cone+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0038191///neuropilin binding GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007409///axonogenesis+++GO:0008360///regulation of cell shape+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0048041///focal adhesion assembly+++GO:0048812///neuron projection morphogenesis+++GO:0051403///stress-activated MAPK cascade+++GO:0099179///regulation of synaptic membrane adhesion+++GO:0150019///basal dendrite morphogenesis+++GO:0150020///basal dendrite arborization 381922 381922 'Cdiptos' mRNA 11 6 6 0.67 0.37 0.43 1.43 1.29 1.57 0.49 1.43 26 23 25 7.666666667 24.66666667 0.01106575 1.676851153 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 381925 381925 'Plpp4' mRNA 3 0 4 0.17 0 0.24 0 0.15 0 0.136666667 0.05 0 3 0 2.333333333 1 0.664230236 -1.244425026 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000810///diacylglycerol diphosphate phosphatase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042577///lipid phosphatase activity+++GO:0042802///identical protein binding GO:0001835///blastocyst hatching+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0046839///phospholipid dephosphorylation+++GO:0090279///regulation of calcium ion import 381933 381933 'Spef1l' mRNA 77 70 72 4.46 4.21 4.67 0.81 1.42 0.67 4.446666667 0.966666667 17 26 13 73 18.66666667 6.48E-07 -1.977609702 GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005902///microvillus+++GO:0005930///axoneme+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium GO:0003779///actin binding+++GO:0008017///microtubule binding GO:0030032///lamellipodium assembly+++GO:0046847///filopodium assembly+++GO:0051493///regulation of cytoskeleton organization+++GO:0060548///negative regulation of cell death 381979 381979 'Brsk1' mRNA 98.72 69.8 57.54 1.9 1.31 1.11 0.33 0.32 0.18 1.44 0.276666667 21 19.66 11 75.35333333 17.22 2.37E-07 -2.141853726 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0150034///distal axon GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0043015///gamma-tubulin binding+++GO:0046872///metal ion binding+++GO:0050321///tau-protein kinase activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007269///neurotransmitter secretion+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0008306///associative learning+++GO:0009411///response to UV+++GO:0010975///regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0030182///neuron differentiation+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:0048167///regulation of synaptic plasticity+++GO:0048812///neuron projection morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0051298///centrosome duplication+++GO:0090176///microtubule cytoskeleton organization involved in establishment of planar polarity+++GO:0099504///synaptic vesicle cycle 381983 381983 'Lmtk3' mRNA 47 38 27 0.38 0.3 0.23 0.08 0.15 0.09 0.303333333 0.106666667 12 21 13 37.33333333 15.33333333 0.015166716 -1.284128197 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0010923///negative regulation of phosphatase activity+++GO:0016310///phosphorylation 381990 381990 'Zbtb2' mRNA 827.13 878.26 777.91 5.45 5.2 5.23 4.93 4.6 4.39 5.293333333 4.64 785.9 675.4 758.08 827.7666667 739.7933333 0.1088416 -0.173513593 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 381994 381994 'E030018B13Rik' mRNA 4 2 4 0.25 0.12 0.27 0.33 0.28 0.4 0.213333333 0.336666667 6 5 7 3.333333333 6 0.54780023 0.828481994 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 382010 382010 'Cep44' mRNA 348.8 388.62 380.27 7.57 7.64 8.3 6.69 8.19 7.96 7.836666667 7.613333333 355.57 348.43 367.69 372.5633333 357.23 0.687086217 -0.073446872 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0008017///microtubule binding GO:0007098///centrosome cycle+++GO:0007099///centriole replication+++GO:0010457///centriole-centriole cohesion 382014 382014 'Ano8' mRNA 14 14 3 0.2 0.19 0.04 0.03 0.09 0.14 0.143333333 0.086666667 2 7 11 10.33333333 6.666666667 0.608596619 -0.613118491 GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0017128///phospholipid scramblase activity GO:0006821///chloride transport+++GO:0055085///transmembrane transport 382018 382018 'Unc13a' mRNA 248 200 197 1.67 1.31 1.45 0.29 0.24 0.28 1.476666667 0.27 49 40 45 215 44.66666667 4.63E-22 -2.278464257 04721///Synaptic vesicle cycle GO:0005737///cytoplasm+++GO:0005798///Golgi-associated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098793///presynapse+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse GO:0000149///SNARE binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005543///phospholipid binding+++GO:0017075///syntaxin-1 binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0019992///diacylglycerol binding+++GO:0030507///spectrin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding "GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0007269///neurotransmitter secretion+++GO:0007528///neuromuscular junction development+++GO:0010807///regulation of synaptic vesicle priming+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0030154///cell differentiation+++GO:0031915///positive regulation of synaptic plasticity+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035556///intracellular signal transduction+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050435///amyloid-beta metabolic process+++GO:0060291///long-term synaptic potentiation+++GO:0060384///innervation+++GO:0061789///dense core granule priming+++GO:0061790///dense core granule docking+++GO:0099011///neuronal dense core vesicle exocytosis+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:1900451///positive regulation of glutamate receptor signaling pathway+++GO:1902991///regulation of amyloid precursor protein catabolic process+++GO:1903861///positive regulation of dendrite extension" 382019 382019 'Zfp882' mRNA 316.12 314.92 309.59 2.97 2.91 3.09 1.44 1.71 2.02 2.99 1.723333333 176.05 204.31 238.91 313.5433333 206.4233333 3.81E-04 -0.61399588 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 382030 382030 'Cnep1r1' mRNA 638 704 614 20.77 22.69 21.28 22.82 19.42 22.71 21.58 21.65 812 674 787 652 757.6666667 0.077550392 0.205179154 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0071595///Nem1-Spo7 phosphatase complex GO:0003674///molecular_function GO:0006629///lipid metabolic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0034504///protein localization to nucleus+++GO:0035307///positive regulation of protein dephosphorylation 382034 382034 'Gse1' mRNA 343 293 256 2.66 2.15 2.07 2.82 2.89 3.01 2.293333333 2.906666667 424 419 432.23 297.3333333 425.0766667 4.36E-04 0.506959271 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 382035 382035 'Pabpn1l' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 03015///mRNA surveillance pathway+++05164///Influenza A GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008143///poly(A) binding GO:0008150///biological_process 382038 382038 'Urb2' mRNA 147 163 136 1.31 1.45 1.31 1.91 1.45 1.85 1.356666667 1.736666667 243 181 229 148.6666667 217.6666667 0.007022827 0.538547417 GO:0005730///nucleolus+++GO:0016235///aggresome+++GO:0030496///midbody GO:0003674///molecular_function GO:0042254///ribosome biogenesis 382045 382045 'Adgrg5' mRNA 17 13 15 0.32 0.25 0.3 1.96 2.12 1.61 0.29 1.896666667 117 123 94 15 111.3333333 8.17E-16 2.879985562 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 382051 382051 'Pdp2' mRNA 1166 1197 1055 11.03 11.1 10.6 7.25 6.8 7.28 10.91 7.11 883 810 857 1139.333333 850 6.43E-07 -0.43311547 GO:0005739///mitochondrion GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004741///[pyruvate dehydrogenase (lipoamide)] phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:1904184///positive regulation of pyruvate dehydrogenase activity 382056 382056 'Crtc1' mRNA 1087 1131 907 10.17 10.4 9.02 6.55 6.57 6.42 9.863333333 6.513333333 805 793 769 1041.666667 789 2.00E-05 -0.408847486 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008140///cAMP response element binding protein binding GO:0007613///memory+++GO:0008152///metabolic process+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0051289///protein homotetramerization+++GO:0097009///energy homeostasis+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:1900006///positive regulation of dendrite development+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1902631///negative regulation of membrane hyperpolarization 382062 382062 'AB124611' mRNA 668 711 665 31.22 33.27 33.19 28.37 28.88 27.67 32.56 28.30666667 695 690 651 681.3333333 678.6666667 0.897778815 -0.017170909 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 382064 382064 'Gm1110' mRNA 0 0 1 0 0 0.03 0.02 0 0 0.01 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005773///vacuole "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004565///beta-galactosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0008150///biological_process+++GO:0008152///metabolic process 382066 382066 'Prdm10' mRNA 175.98 234.95 192.01 2.26 2.64 2.6 2.75 2.99 2.83 2.5 2.856666667 264 243 245 200.98 250.6666667 0.100151677 0.312502455 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0010468///regulation of gene expression+++GO:0032259///methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II 382073 382073 'Ccdc84' mRNA 292.22 305.13 284.18 14.93 15.29 15.35 15.36 15.99 14.62 15.19 15.32333333 344.38 354.12 322.16 293.8433333 340.22 0.210556163 0.200361985 GO:0005813///centrosome GO:0003674///molecular_function GO:0010826///negative regulation of centrosome duplication+++GO:0042176///regulation of protein catabolic process 382074 382074 'Foxr1' mRNA 3 1.97 2.93 0.1 0.07 0.11 0 0.03 0.17 0.093333333 0.066666667 0 1 5.51 2.633333333 2.17 0.998591786 -0.006770249 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated" 382075 382075 'Odf3l1' mRNA 10 14 11 0.45 0.66 0.49 0.35 0.42 0.42 0.533333333 0.396666667 7 10 10 11.66666667 9 0.702435258 -0.381261122 GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 382077 382077 'Ccdc33' mRNA 2161 2114 2087 36.86 36.17 38.51 2.76 2.89 3.45 37.18 3.033333333 185 177 202 2120.666667 188 7.41E-271 -3.507971393 GO:0005777///peroxisome GO:0003674///molecular_function GO:0007283///spermatogenesis 382083 382083 'Snx22' mRNA 1240.37 1228.67 1197.71 27.01 26.34 27.7 18.13 17.84 17.61 27.01666667 17.86 957.88 920.24 900.82 1222.25 926.3133333 1.42E-06 -0.41241037 GO:0005575///cellular_component GO:0035091///phosphatidylinositol binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0008150///biological_process 382089 382089 'Ripply2' mRNA 1 1 3 0.05 0.06 0.16 0.05 0 0 0.09 0.016666667 1 0 0 1.666666667 0.333333333 0.4595807 -2.257178103 GO:0005634///nucleus GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001503///ossification+++GO:0001756///somitogenesis+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0009798///axis specification+++GO:0009880///embryonic pattern specification+++GO:0010468///regulation of gene expression+++GO:0032525///somite rostral/caudal axis specification+++GO:0036342///post-anal tail morphogenesis+++GO:0060349///bone morphogenesis 382090 382090 'Cep162' mRNA 629 622 622 8.24 7.31 7.88 5.75 5.36 5.44 7.81 5.516666667 514 447 462 624.3333333 474.3333333 4.13E-04 -0.409837819 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005879///axonemal microtubule GO:0005515///protein binding GO:0030030///cell projection organization+++GO:0060271///cilium assembly 382099 382099 'Gm5161' mRNA 1 0 1 0.08 0 0.08 0.13 0 0.07 0.053333333 0.066666667 2 0 1 0.666666667 1 0.876586799 0.539037703 382105 382105 'Fbxw15' mRNA 0 0 1 0 0 0.04 0.1 0 0 0.013333333 0.033333333 3 0 0 0.333333333 1 0.753813172 1.439504619 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 382111 382111 'Susd5' mRNA 40 52 48 0.56 0.71 0.71 1.24 1.03 1.08 0.66 1.116666667 102 83 86 46.66666667 90.33333333 0.002465322 0.938856177 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005540///hyaluronic acid binding GO:0007155///cell adhesion+++GO:0007219///Notch signaling pathway 382117 382117 'Tcaim' mRNA 320 278.44 348 5.37 4.68 6.47 4.84 4.54 3.68 5.506666667 4.353333333 315 299 234 315.48 282.6666667 0.394227551 -0.175110854 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 382118 382118 'Zkscan7' mRNA 435.59 465.52 436.99 4.68 4.94 5 2.16 1.87 2.24 4.873333333 2.09 233 196.66 231.56 446.0333333 220.4066667 2.73E-13 -1.02993935 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 382137 382137 'Fdxacb1' mRNA 135 104 112 3.93 2.97 3.42 4.67 4.14 3.97 3.44 4.26 184 160 151 117 165 0.035303711 0.482944889 GO:0005737///cytoplasm GO:0070042///rRNA (uridine-N3-)-methyltransferase activity GO:0070475///rRNA base methylation 382207 382207 'Jade3' mRNA 65 66 77 0.71 0.7 0.89 0.91 0.78 1.02 0.766666667 0.903333333 96 82 103 69.33333333 93.66666667 0.176183647 0.417740887 GO:0000123///histone acetyltransferase complex GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0043966///histone H3 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation 382217 382217 'Gm1140' mRNA 0.39 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.13 0 GO:0000795///synaptonemal complex GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 382231 382231 '8030474K03Rik' mRNA 5.57 1 10 0.21 0.05 0.26 0.17 0.21 0.13 0.173333333 0.17 6 8 3 5.523333333 5.666666667 0.979830626 0.047379357 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 382236 382236 'Brwd3' mRNA 256 232 192 1.06 0.95 0.83 0.95 0.72 0.87 0.946666667 0.846666667 268 200 236 226.6666667 234.6666667 0.863090843 0.040042284 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape 382244 382244 'Gm15091' mRNA 8 0 1.49 0.22 0 0.04 0.11 0.11 0.14 0.086666667 0.12 4.7 4.55 5.6 3.163333333 4.95 0.784026243 0.531996282 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 382245 382245 'Tmem29' mRNA 348 379 415 16.36 17.66 20.44 14.21 15.59 12.73 18.15333333 14.17666667 344 367 298 380.6666667 336.3333333 0.269699819 -0.193587343 GO:0005635///nuclear envelope GO:0003674///molecular_function+++GO:0035064///methylated histone binding GO:0008150///biological_process 382252 382252 'Bclaf3' mRNA 411 400 389 6.68 6.38 6.75 5.53 5.83 5.61 6.603333333 5.656666667 391 401 383 400 391.6666667 0.81918928 -0.041698635 GO:0005739///mitochondrion+++GO:0016592///mediator complex GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity GO:0045944///positive regulation of transcription by RNA polymerase II 382253 382253 'Cdkl5' mRNA 39 40 38 0.66 0.66 0.68 0.59 0.43 0.59 0.666666667 0.536666667 40 29 39 39 36 0.817854462 -0.128883091 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0032839///dendrite cytoplasm+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0044294///dendritic growth cone+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097542///ciliary tip+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0034504///protein localization to nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0045773///positive regulation of axon extension+++GO:0046777///protein autophosphorylation+++GO:0050773///regulation of dendrite development+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051726///regulation of cell cycle+++GO:0060999///positive regulation of dendritic spine development+++GO:0099175///regulation of postsynapse organization+++GO:1902017///regulation of cilium assembly 382384 382384 'Odf3l2' mRNA 22 36 27 1.07 1.74 1.4 0.48 0.05 0.35 1.403333333 0.293333333 11 1 8 28.33333333 6.666666667 0.003139469 -2.105501453 GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule GO:0003674///molecular_function GO:0008150///biological_process 382395 382395 'Gm5174' mRNA 26.33 41.65 26.49 0.2 0.31 0.21 0.05 0.06 0.08 0.24 0.063333333 8 9.15 12.62 31.49 9.923333333 0.004271956 -1.685632347 382406 382406 'Poc1b' mRNA 321 293 183 6.09 5.45 3.66 5.25 5.66 5.23 5.066666667 5.38 320 337 308 265.6666667 321.6666667 0.178210415 0.274177702 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0001895///retina homeostasis+++GO:0007099///centriole replication+++GO:0008283///cell proliferation+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly 382423 382423 'Atxn7l3b' mRNA 3753 3885 3691 56.62 57.66 59.06 38.34 40.33 37.7 57.78 38.79 2925 3005 2785 3776.333333 2905 1.47E-09 -0.389904786 GO:0005737///cytoplasm GO:0010468///regulation of gene expression 382427 382427 'Best3' mRNA 110.6 93.99 120.05 1.16 0.87 1.25 0.42 0.53 0.43 1.093333333 0.46 51.14 67.63 56.57 108.2133333 58.44666667 0.001968363 -0.907202594 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005254///chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0015698///inorganic anion transport+++GO:0043271///negative regulation of ion transport 382523 382523 'H3f4' mRNA 2 1 3 0.28 0.14 0.45 0.12 0.38 0.13 0.29 0.21 1 3 1 2 1.666666667 0.898937607 -0.283988041 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus 382543 382543 'Ankfn1' mRNA 922 889 715 9.42 8.92 7.74 0.86 1 0.75 8.693333333 0.87 97 110 82 842 96.33333333 2.03E-99 -3.134600975 GO:0005819///spindle GO:0003674///molecular_function GO:0000132///establishment of mitotic spindle orientation+++GO:0001662///behavioral fear response+++GO:0045475///locomotor rhythm+++GO:0050957///equilibrioception+++GO:0061172///regulation of establishment of bipolar cell polarity 382551 382551 'Cd300ld3' mRNA 0.84 0 2.03 0.07 0 0.17 2.18 2.83 0.91 0.08 1.973333333 30.81 37.82 12.73 0.956666667 27.12 3.65E-05 5.280403307 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0002376///immune system process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway 382562 382562 'Pfn4' mRNA 27 20.26 31.51 0.84 0.64 1.19 0.51 0.64 0.7 0.89 0.616666667 16.22 23 20.33 26.25666667 19.85 0.510307975 -0.419162333 04013///MAPK signaling pathway - fly+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++05014///Amyotrophic lateral sclerosis+++05131///Shigellosis+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0008289///lipid binding GO:0042989///sequestering of actin monomers 382571 382571 'Kcnf1' mRNA 65 89 72 0.73 0.98 0.85 0.17 0.24 0.22 0.853333333 0.21 17 24 22 75.33333333 21 9.75E-07 -1.850870622 GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097546///ciliary base GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:1905515///non-motile cilium assembly 382620 382620 'Tmed8' mRNA 1454 1362 1211.65 9.1 8.43 7.95 3.83 3.84 3.69 8.493333333 3.786666667 691 676 642 1342.55 669.6666667 1.14E-29 -1.012762237 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 382639 382639 'Zbtb42' mRNA 259 231 264 4.04 3.55 4.37 5.22 4.96 5.4 3.986666667 5.193333333 385 357 386 251.3333333 376 1.84E-04 0.56661738 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development 382793 382793 'Mtx3' mRNA 347 373 360 2.97 3.12 3.27 1.98 1.58 1.84 3.12 1.8 270 209 241 360 240 1.08E-04 -0.599022567 GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0007005///mitochondrion organization+++GO:0015031///protein transport 382864 382864 'Colq' mRNA 19 28 16 0.4 0.58 0.34 0.14 0.24 0.08 0.44 0.153333333 7 15 4 21 8.666666667 0.089413006 -1.274977903 GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0008201///heparin binding GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0030198///extracellular matrix organization+++GO:0042135///neurotransmitter catabolic process+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0090150///establishment of protein localization to membrane 382867 382867 'Zfp488' mRNA 693.67 696.36 576.81 8.2 8.02 7.03 4.45 3.12 3.75 7.75 3.773333333 441.37 303.27 357.12 655.6133333 367.2533333 4.44E-10 -0.847003234 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0014003///oligodendrocyte development+++GO:0031643///positive regulation of myelination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048714///positive regulation of oligodendrocyte differentiation" 382913 382913 'Neil2' mRNA 55 68 50 1.54 1.93 1.37 1.19 0.89 1.19 1.613333333 1.09 44 37 49 57.66666667 43.33333333 0.29066452 -0.420557347 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072686///mitotic spindle "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016829///lyase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0046872///metal ion binding+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity" GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process 382985 382985 'Rrm2b' mRNA 681 737 705 10.47 10.12 10.32 5.08 4.84 6.02 10.30333333 5.313333333 478 425 443 707.6666667 448.6666667 1.41E-09 -0.670377182 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00480///Glutathione metabolism+++00983///Drug metabolism - other enzymes+++04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004748///ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0001822///kidney development+++GO:0003014///renal system process+++GO:0006260///DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0009200///deoxyribonucleoside triphosphate metabolic process+++GO:0009263///deoxyribonucleotide biosynthetic process+++GO:0014075///response to amine+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 383075 383075 'Enthd1' mRNA 0 1 0 0 0.03 0 0.03 0.05 0 0.01 0.026666667 1 2 0 0.333333333 1 0.731322811 1.474625849 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0030125///clathrin vesicle coat+++GO:0043231///intracellular membrane-bounded organelle GO:0005543///phospholipid binding+++GO:0030276///clathrin binding GO:0006897///endocytosis 383103 383103 'Tvp23a' mRNA 316.22 311.78 263.53 4.48 4.48 3.88 2.56 2.2 2.11 4.28 2.29 235.87 187.52 181.52 297.1766667 201.6366667 8.06E-04 -0.572391739 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0003674///molecular_function GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport 383258 383258 'Vmn2r118' mRNA 0 0 1 0 0 0.02 0.04 0 0 0.006666667 0.013333333 2 0 0 0.333333333 0.666666667 0.863090843 0.855344965 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 383295 383295 'Ypel5' mRNA 2441 2521 2459 62.01 63.07 66.33 71.23 71.28 67.51 63.80333333 70.00666667 3206 3140 2951 2473.666667 3099 4.81E-06 0.31267972 GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0097431///mitotic spindle pole GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0008283///cell proliferation 383348 383348 'Kctd16' mRNA 67.89 49 66.51 0.19 0.14 0.2 0.12 0.08 0.05 0.176666667 0.083333333 48 30 18 61.13333333 32 0.030320587 -0.944650505 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0003674///molecular_function GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0051260///protein homooligomerization 383435 383435 'Ms4a14' mRNA 3 4 6 0.04 0.05 0.09 1.59 1.3 1.45 0.06 1.446666667 143 115 122 4.333333333 126.6666667 7.68E-23 4.853944593 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 383491 383491 'Prdm14' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0001708///cell fate specification+++GO:0001827///inner cell mass cell fate commitment+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007281///germ cell development+++GO:0007566///embryo implantation+++GO:0009566///fertilization+++GO:0010468///regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0030718///germ-line stem cell population maintenance+++GO:0032259///methylation+++GO:0034972///histone H3-R26 methylation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0044030///regulation of DNA methylation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0060817///inactivation of paternal X chromosome+++GO:1902093///positive regulation of flagellated sperm motility+++GO:1902459///positive regulation of stem cell population maintenance" 383563 383563 'Gpr25' mRNA 12 13 6 0.34 0.36 0.18 0 0.03 0.03 0.293333333 0.02 0 1 1 10.33333333 0.666666667 0.008197457 -3.947241182 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 383592 383592 'Kif28' mRNA 878 859 847 12.78 12.3 13.07 0.96 0.96 0.84 12.71666667 0.92 76 74 64 861.3333333 71.33333333 4.58E-132 -3.606323737 GO:0005739///mitochondrion+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0007005///mitochondrion organization+++GO:0007018///microtubule-based movement+++GO:0072384///organelle transport along microtubule 383619 383619 'Aim2' mRNA 12.51 18.03 18.47 0.19 0.22 0.22 1.72 1.13 1.62 0.21 1.49 119 85.86 126.57 16.33666667 110.4766667 2.86E-14 2.765908278 04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0097169///AIM2 inflammasome complex GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032611///interleukin-1 beta production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0035458///cellular response to interferon-beta+++GO:0035690///cellular response to drug+++GO:0044546///NLRP3 inflammasome complex assembly+++GO:0045087///innate immune response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070269///pyroptosis+++GO:0071466///cellular response to xenobiotic stimulus+++GO:1904270///pyroptosome complex assembly+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 383678 383678 'Obp2b' mRNA 49 71 61 1.88 3.44 3.07 0.06 0.36 0.39 2.796666667 0.27 3 10.67 9 60.33333333 7.556666667 3.74E-09 -3.047709997 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0036094///small molecule binding GO:0008150///biological_process 383709 383709 'Gm1322' mRNA 3976 3926 3648 115.36 112.23 112.29 8.53 8.45 8.27 113.2933333 8.416666667 338 327 317 3850 327.3333333 0 -3.567049936 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 383766 383766 'Tldc2' mRNA 7.58 7.46 20.12 0.1 0.21 0.51 0.14 0.15 0.05 0.273333333 0.113333333 9.38 22.95 7.97 11.72 13.43333333 0.898688989 0.130845421 GO:0005634///nucleus GO:0003674///molecular_function GO:0006979///response to oxidative stress+++GO:1903204///negative regulation of oxidative stress-induced neuron death 383787 383787 'Ankrd63' mRNA 0 0 2 0 0 0.02 0.01 0 0.03 0.006666667 0.013333333 1 0 3 0.666666667 1.333333333 0.804603501 0.92863865 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 384009 384009 'Glipr2' mRNA 99 116 104 2.79 3.22 3.11 16.54 15.99 16.33 3.04 16.28666667 675 637 645 106.3333333 652.3333333 1.31E-74 2.605642033 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0042803///protein homodimerization activity GO:0010634///positive regulation of epithelial cell migration+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 384059 384059 'Tlr12' mRNA 9 2 1 0.16 0.03 0.02 0.25 0.17 0.14 0.07 0.186666667 17 11 9 4 12.33333333 0.12484601 1.622906072 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0038023///signaling receptor activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0009617///response to bacterium+++GO:0042832///defense response to protozoan+++GO:0045087///innate immune response 384061 384061 'Fndc5' mRNA 302 315 291 6.04 6.2 6.17 6.43 6.04 6.74 6.136666667 6.403333333 371 340 376 302.6666667 362.3333333 0.099082873 0.24812213 GO:0005576///extracellular region+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005179///hormone activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0014850///response to muscle activity+++GO:0090336///positive regulation of brown fat cell differentiation 384071 384071 'Slc25a34' mRNA 104 89 93 2.14 1.79 2.03 1.72 1.49 1.41 1.986666667 1.54 96 82 76 95.33333333 84.66666667 0.574449377 -0.184630158 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001835///blastocyst hatching 384077 384077 'Pramel5' mRNA 3 4 2 0.08 0.1 0.06 0.05 0 0 0.08 0.016666667 2 0 0 3 0.666666667 0.350547788 -2.188313438 GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 384185 384185 'Arl9' mRNA 7 9 15 0.17 0.2 0.38 0.31 0.08 0.21 0.25 0.2 16 4 10 10.33333333 10 0.940429164 -0.082657641 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008150///biological_process 384198 384198 'Fam47e' mRNA 3 4 5 0.11 0.2 0.2 0 0 0.19 0.17 0.063333333 0 0 4 4 1.333333333 0.42369419 -1.600373711 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008047///enzyme activator activity GO:0050790///regulation of catalytic activity 384214 384214 'Ephx4' mRNA 85 88 72 4.18 4.21 3.7 1.61 1.46 2.08 4.03 1.716666667 38 34 48 81.66666667 40 0.001565787 -1.038316816 05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0016787///hydrolase activity 384219 384219 'Vmn2r11' mRNA 0 0.5 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.166666667 0 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 384244 384244 'Foxl3' mRNA 0 7 5 0 0.79 0.6 0.1 0.31 0 0.463333333 0.136666667 1 3 0 4 1.333333333 0.447784259 -1.593168483 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation" 384281 384281 'Gatc' mRNA 1103 1235 1123 35.83 39.54 38.7 23.71 23.05 24.1 38.02333333 23.62 839 796 825 1153.666667 820 2.08E-08 -0.504076864 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0030956///glutamyl-tRNA(Gln) amidotransferase complex "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0016884///carbon-nitrogen ligase activity, with glutamine as amido-N-donor+++GO:0050567///glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity" GO:0006412///translation+++GO:0006450///regulation of translational fidelity+++GO:0032543///mitochondrial translation+++GO:0070681///glutaminyl-tRNAGln biosynthesis via transamidation 384309 384309 'Trim56' mRNA 589.41 604.43 456.24 10.83 11.03 8.89 8.83 8.18 9.53 10.25 8.846666667 536.19 489.67 581.44 550.0266667 535.7666667 0.797480756 -0.045120909 GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0002376///immune system process+++GO:0032728///positive regulation of interferon-beta production+++GO:0034340///response to type I interferon+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0070534///protein K63-linked ubiquitination+++GO:1902187///negative regulation of viral release from host cell" 384534 384534 'Vmn2r52' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 384557 384557 'Ceacam3' mRNA 14 2 8 0.19 0.03 0.11 0.17 0.14 0.06 0.11 0.123333333 15 8 4 8 9 0.904933458 0.145358223 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 384569 384569 'Nova2' mRNA 85 101 63 0.53 0.62 0.42 0.35 0.48 0.34 0.523333333 0.39 64 86 60 83 70 0.503846268 -0.247662151 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:1990825///sequence-specific mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010468///regulation of gene expression+++GO:0021954///central nervous system neuron development+++GO:0030182///neuron differentiation+++GO:0051252///regulation of RNA metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1902667///regulation of axon guidance" 384605 384605 'Wdr88' mRNA 2 3 4 0.05 0.07 0.11 0 0 0.13 0.076666667 0.043333333 0 0 6 3 2 0.804537619 -0.601786099 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 384619 384619 'Kash5' mRNA 23 19 15 0.52 0.43 0.4 0.24 0.08 0.17 0.45 0.163333333 12 4 9 19 8.333333333 0.109831685 -1.201272624 "GO:0000781///chromosome, telomeric region+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0090619///meiotic spindle pole" GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0070840///dynein complex binding GO:0000724///double-strand break repair via homologous recombination+++GO:0007015///actin filament organization+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0034397///telomere localization+++GO:0048477///oogenesis+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0090172///microtubule cytoskeleton organization involved in homologous chromosome segregation+++GO:0090220///chromosome localization to nuclear envelope involved in homologous chromosome segregation 384724 384724 'Cyp2t4' mRNA 9 13 5 0.35 0.5 0.21 0.1 0.17 0.18 0.353333333 0.15 3 5 5 9 4.333333333 0.34858779 -1.047675317 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 384763 384763 'Zfp667' mRNA 628 603 624 9.27 8.77 9.8 3.76 3.92 3.54 9.28 3.74 293 296 269 618.3333333 286 9.88E-20 -1.125315291 05168///Herpes simplex virus 1 infection GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 384783 384783 'Irs2' mRNA 963 944 908 7.49 7.22 7.49 4.47 4.72 4.64 7.4 4.61 661 682 666 938.3333333 669.6666667 1.84E-07 -0.497773988 "04022///cGMP-PKG signaling pathway+++04068///FoxO signaling pathway+++04140///Autophagy - animal+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05206///MicroRNAs in cancer" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0071889///14-3-3 protein binding GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0002903///negative regulation of B cell apoptotic process+++GO:0007165///signal transduction+++GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0009749///response to glucose+++GO:0010748///negative regulation of plasma membrane long-chain fatty acid transport+++GO:0010907///positive regulation of glucose metabolic process+++GO:0030335///positive regulation of cell migration+++GO:0030879///mammary gland development+++GO:0030890///positive regulation of B cell proliferation+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0032024///positive regulation of insulin secretion+++GO:0032869///cellular response to insulin stimulus+++GO:0033673///negative regulation of kinase activity+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0046326///positive regulation of glucose import+++GO:0071333///cellular response to glucose stimulus+++GO:1901653///cellular response to peptide 384806 384806 'Adam20' mRNA 1.48 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.493333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990913///sperm head plasma membrane GO:0003674///molecular_function+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0008584///male gonad development 385024 385024 'Gm5373' mRNA 2.47 6.37 3.89 0.05 0.13 0.08 0.06 0.05 0.06 0.086666667 0.056666667 3.06 2 3 4.243333333 2.686666667 0.802709994 -0.465431043 385138 385138 'BC061237' mRNA 1 0 0 0.1 0 0 0.09 0 0.09 0.033333333 0.06 1 0 1 0.333333333 0.666666667 0.863090843 0.873439817 GO:0003674///molecular_function GO:0008150///biological_process 385263 385263 'Gm1527' mRNA 5 5 4 0.19 0.19 0.16 0 0 0 0.18 0 0 0 0 4.666666667 0 0.023027937 -4.672603181 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity 385354 385354 'Frmd7' mRNA 0 1.06 0 0 0.01 0 0 0.01 0 0.003333333 0.003333333 0 1.12 0 0.353333333 0.373333333 0.998591786 -0.011756601 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0007399///nervous system development+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010975///regulation of neuron projection development+++GO:0032091///negative regulation of protein binding+++GO:0050790///regulation of catalytic activity+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051497///negative regulation of stress fiber assembly 385377 385377 'Pnma5' mRNA 21.41 31 16 0.52 0.68 0.36 0.23 0.22 0.15 0.52 0.2 11 10 7 22.80333333 9.333333333 0.05767656 -1.282806122 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 385454 385454 'Gm5396' mRNA 1 1 1 0.14 0.14 0.15 0.49 0.13 0.51 0.143333333 0.376666667 4 1 4 1 3 0.455403413 1.566066803 03410///Base excision repair+++04140///Autophagy - animal+++04217///Necroptosis+++04613///Neutrophil extracellular trap formation 385550 385550 'Srsy' mRNA 0 0 0.5 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.166666667 0 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 385643 385643 'Kng2' mRNA 47.97 66 48 1.74 2.38 1.85 8.59 8.53 8.59 1.99 8.57 272.28 265.03 269.85 53.99 269.0533333 1.09E-27 2.314769113 04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04610///Complement and coagulation cascades+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++05142///Chagas disease+++05143///African trypanosomiasis+++05200///Pathways in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding GO:0006954///inflammatory response+++GO:0007162///negative regulation of cell adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030195///negative regulation of blood coagulation+++GO:0031640///killing of cells of other organism+++GO:0042311///vasodilation+++GO:0045861///negative regulation of proteolysis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 385658 385658 'Nxpe3' mRNA 125.05 98.62 97.94 1.39 1.07 1.14 1.07 0.99 1.2 1.2 1.086666667 110.05 98.87 120.81 107.2033333 109.91 0.940102711 0.024933724 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 385668 385668 'Lca5l' mRNA 53 50 72 0.94 0.87 1.37 0.6 0.47 0.59 1.06 0.553333333 39 29 38 58.33333333 35.33333333 0.063195422 -0.745269637 GO:0005930///axoneme GO:0003674///molecular_function GO:0042073///intraciliary transport 385674 385674 'Zfp174' mRNA 337.33 349.06 324.22 3.25 3.1 3.17 1.46 1.26 1.39 3.173333333 1.37 181.33 159 173 336.87 171.11 2.14E-10 -0.989212048 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 386454 386454 'Rnf39' mRNA 47 41 45 1.93 1.66 1.96 2.36 2.02 2.15 1.85 2.176666667 66 55 58 44.33333333 59.66666667 0.282803304 0.414139872 GO:0005737///cytoplasm GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 386463 386463 'Cdsn' mRNA 5 6 9 0.11 0.13 0.2 0.78 0.51 0.65 0.146666667 0.646666667 42 27 35 6.666666667 34.66666667 1.04E-04 2.356521072 GO:0005576///extracellular region+++GO:0030057///desmosome GO:0042803///protein homodimerization activity GO:0003336///corneocyte desquamation+++GO:0043589///skin morphogenesis+++GO:0098609///cell-cell adhesion+++GO:1905716///negative regulation of cornification 386611 386611 'Rnf133' mRNA 2 3 0 0.09 0.14 0 0 0 0 0.076666667 0 0 0 0 1.666666667 0 0.385064596 -3.153564358 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination 386612 386612 'Thoc6' mRNA 252.33 295.89 278.23 10.17 11.33 11.93 17.79 18.14 16.01 11.14333333 17.31333333 514.94 507.16 439.98 275.4833333 487.36 6.23E-09 0.811018315 03013///Nucleocytoplasmic transport "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016607///nuclear speck" GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0008380///RNA splicing+++GO:0043066///negative regulation of apoptotic process+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport 386649 386649 'Nsfl1c' mRNA 1737 1825 1705 69.38 71.9 72.25 73.25 73.33 75.68 71.17666667 74.08666667 2107 2058 2106 1755.666667 2090.333333 7.99E-04 0.240312543 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0031616///spindle pole centrosome+++GO:0045111///intermediate filament cytoskeleton+++GO:1990730///VCP-NSFL1C complex GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0043130///ubiquitin binding+++GO:0051117///ATPase binding GO:0000045///autophagosome assembly+++GO:0000132///establishment of mitotic spindle orientation+++GO:0007030///Golgi organization+++GO:0031468///nuclear envelope reassembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0046604///positive regulation of mitotic centrosome separation+++GO:0061025///membrane fusion+++GO:1904780///negative regulation of protein localization to centrosome 386655 386655 'Eid2' mRNA 29 41 22 1.36 1.9 1.1 1.23 0.97 1.06 1.453333333 1.086666667 30 23 25 30.66666667 26 0.697265669 -0.242633681 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003714///transcription corepressor activity+++GO:0046332///SMAD binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007181///transforming growth factor beta receptor complex assembly+++GO:0007183///SMAD protein complex assembly+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated" 386750 386750 'Slitrk3' mRNA 106 121 103 1.23 1.37 1.24 0.25 0.28 0.29 1.28 0.273333333 24 28 28 110 26.66666667 4.33E-11 -2.053415614 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0003674///molecular_function+++GO:0005515///protein binding "GO:0007409///axonogenesis+++GO:0051932///synaptic transmission, GABAergic+++GO:0051965///positive regulation of synapse assembly+++GO:0072553///terminal button organization+++GO:0072578///neurotransmitter-gated ion channel clustering+++GO:0097107///postsynaptic density assembly+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly" 386753 386753 'Dbpht2' mRNA 39 37 44 0.72 0.67 0.86 0.05 0 0.07 0.75 0.04 3 0 4 40 2.333333333 5.62E-08 -4.118665168 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 387285 387285 'Hcrtr2' mRNA 1 0 0 0.01 0 0 0.09 0 0 0.003333333 0.03 5 0 0 0.333333333 1.666666667 0.56174096 2.175639361 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0016499///orexin receptor activity+++GO:0017046///peptide hormone binding "GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007631///feeding behavior+++GO:0010840///regulation of circadian sleep/wake cycle, wakefulness+++GO:0022410///circadian sleep/wake cycle process+++GO:0051480///regulation of cytosolic calcium ion concentration" 387314 387314 'Tmtc1' mRNA 402 402 316 2.58 2.53 2.13 1.17 1.15 1.3 2.413333333 1.206666667 208 203 223 373.3333333 211.3333333 5.80E-08 -0.828231203 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity GO:0006396///RNA processing+++GO:0006486///protein glycosylation+++GO:0035269///protein O-linked mannosylation 387353 387353 'Tas2r126' mRNA 11 10 10 0.77 0.7 0.75 0.25 0.06 0.32 0.74 0.21 4 1 5 10.33333333 3.333333333 0.123350653 -1.648182865 04742///Taste transduction GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste 387510 387510 'Ifnk' mRNA 6 9 7 0.49 0.74 0.61 0.14 0 0.15 0.613333333 0.096666667 2 0 2 7.333333333 1.333333333 0.080699757 -2.475564564 04060///Cytokine-cytokine receptor interaction+++04622///RIG-I-like receptor signaling pathway+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding "GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus" 387512 387512 'Tas2r135' mRNA 11 16 19 0.73 1.06 1.35 0 0.18 0 1.046666667 0.06 0 3 0 15.33333333 1 0.001431686 -3.950678918 04742///Taste transduction GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008527///taste receptor activity+++GO:0033038///bitter taste receptor activity GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste 387524 387524 'Znrf2' mRNA 94 106 94 2 2.22 2.12 4.4 4.49 4.77 2.113333333 4.553333333 238 237 250 98 241.6666667 1.30E-11 1.291660463 GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0032991///protein-containing complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 387565 387565 'Cd300c' mRNA 0 0 1 0 0 0.07 0 0 0.06 0.023333333 0.02 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity GO:0002376///immune system process+++GO:0008150///biological_process 387586 387586 'Ssxb5' mRNA 6 3 6 0.21 0.1 0.22 0.03 0.06 0.06 0.176666667 0.05 1 2 2 5 1.666666667 0.304022001 -1.601666156 05202///Transcriptional misregulation in cancer GO:0005634///nucleus GO:0003714///transcription corepressor activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated" 387609 387609 'Zhx2' mRNA 1570 1551 1246 19.31 18.74 16.24 13.45 10.65 13.37 18.09666667 12.49 1258 977 1215 1455.666667 1150 8.62E-04 -0.349289034 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006402///mRNA catabolic process+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0045665///negative regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060040///retinal bipolar neuron differentiation" 394432 394432 'Ugt1a7c' mRNA 32.55 28.01 21.57 0.54 0.46 0.38 9.41 9.79 8.91 0.46 9.37 653.32 664.06 598.89 27.37666667 638.7566667 5.62E-107 4.554222343 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++00860///Porphyrin metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004857///enzyme inhibitor activity+++GO:0005080///protein kinase C binding+++GO:0005496///steroid binding+++GO:0005504///fatty acid binding+++GO:0008144///drug binding+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" GO:0006711///estrogen catabolic process+++GO:0008210///estrogen metabolic process+++GO:0019439///aromatic compound catabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0046226///coumarin catabolic process+++GO:0052695///cellular glucuronidation+++GO:0052696///flavonoid glucuronidation+++GO:0052697///xenobiotic glucuronidation 394434 394434 'Ugt1a9' mRNA 2.09 0 0 0.04 0 0 0.04 0.08 0 0.013333333 0.04 2.88 5.16 0 0.696666667 2.68 0.529127799 1.822280999 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++00860///Porphyrin metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004857///enzyme inhibitor activity+++GO:0005080///protein kinase C binding+++GO:0005496///steroid binding+++GO:0005504///fatty acid binding+++GO:0008144///drug binding+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" GO:0052696///flavonoid glucuronidation+++GO:0052697///xenobiotic glucuronidation 394435 394435 'Ugt1a6b' mRNA 60.9 73.57 51.37 1.49 1.77 1.33 2.91 3.58 3.71 1.53 3.4 136.47 164.06 168.49 61.94666667 156.34 8.84E-08 1.341578705 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++00860///Porphyrin metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004857///enzyme inhibitor activity+++GO:0005080///protein kinase C binding+++GO:0005496///steroid binding+++GO:0005504///fatty acid binding+++GO:0008144///drug binding+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity" GO:0006805///xenobiotic metabolic process+++GO:0018880///4-chlorobiphenyl metabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0052695///cellular glucuronidation+++GO:0052696///flavonoid glucuronidation+++GO:0052697///xenobiotic glucuronidation+++GO:0071385///cellular response to glucocorticoid stimulus 396184 396184 'Flrt1' mRNA 1711 1696 1588 8.09 7.98 8.09 4.51 4.14 4.35 8.053333333 4.333333333 1087 970 1029 1665 1028.666667 6.99E-20 -0.706502912 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044306///neuron projection terminus+++GO:0048471///perinuclear region of cytoplasm GO:0005104///fibroblast growth factor receptor binding GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0016358///dendrite development+++GO:0051965///positive regulation of synapse assembly+++GO:1990138///neuron projection extension 399510 399510 'Map4k5' mRNA 896 914 371 10.81 10.84 4.75 3.45 4.32 5.38 8.8 4.383333333 329 403 498 727 410 0.075989139 -0.816330888 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 399548 399548 'Scn4b' mRNA 33 41 44 0.37 0.45 0.53 1.9 1.65 1.62 0.45 1.723333333 194 165 160 39.33333333 173 2.44E-16 2.12136866 04261///Adrenergic signaling in cardiomyocytes GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005272///sodium channel activity+++GO:0017080///sodium channel regulator activity+++GO:0044325///ion channel binding+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0010765///positive regulation of sodium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0060048///cardiac muscle contraction+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086016///AV node cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:2000649///regulation of sodium ion transmembrane transporter activity 399558 399558 'Flrt2' mRNA 534 495 338 3.79 3.47 2.6 2.48 2.84 2.78 3.286666667 2.7 390 450 430 455.6666667 423.3333333 0.581570002 -0.108496625 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0045499///chemorepellent activity GO:0003007///heart morphogenesis+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0050919///negative chemotaxis+++GO:0051965///positive regulation of synapse assembly+++GO:0061343///cell adhesion involved in heart morphogenesis+++GO:0071711///basement membrane organization+++GO:2001222///regulation of neuron migration 399566 399566 'Btbd6' mRNA 924 993 764 23.67 24.98 20.95 12.63 14.92 12.81 23.2 13.45333333 549 635 549 893.6666667 577.6666667 2.56E-08 -0.63549407 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0022008///neurogenesis 399568 399568 'Cdin1' mRNA 168 212 171 3.31 4.1 3.57 2.48 2.29 2.7 3.66 2.49 145 131 152 183.6666667 142.6666667 0.081840802 -0.374409924 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0030218///erythrocyte differentiation 399591 399591 'Tmsb15l' mRNA 147.5 107.8 116.54 12.14 8.79 10.18 6.92 7.84 7.15 10.37 7.303333333 96.32 106.19 96.06 123.9466667 99.52333333 0.241979686 -0.322850394 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0031941///filamentous actin GO:0003785///actin monomer binding GO:0007015///actin filament organization+++GO:0030334///regulation of cell migration+++GO:0030837///negative regulation of actin filament polymerization+++GO:0042989///sequestering of actin monomers+++GO:0051497///negative regulation of stress fiber assembly 399599 399599 'Ccdc87' mRNA 195 187 151 3.37 3.18 2.77 0.39 0.42 0.39 3.106666667 0.4 26 27 25 177.6666667 26 3.58E-24 -2.780016417 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0030154///cell differentiation+++GO:1905516///positive regulation of fertilization+++GO:2000344///positive regulation of acrosome reaction 399603 399603 'Lratd2' mRNA 953 1035 1014 9.11 9.73 10.29 8.85 8.13 8.49 9.71 8.49 1066 956 990 1000.666667 1004 0.945847514 -0.008727868 GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 403088 403088 'Tcaf3' mRNA 24 18 19 0.42 0.31 0.36 0.03 0.06 0.02 0.363333333 0.036666667 2 4 1 20.33333333 2.333333333 4.47E-04 -3.132104659 GO:0005886///plasma membrane+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0044325///ion channel binding GO:0010359///regulation of anion channel activity+++GO:0010360///negative regulation of anion channel activity+++GO:0030335///positive regulation of cell migration+++GO:0090314///positive regulation of protein targeting to membrane 403174 403174 'Msantd1' mRNA 28 35 34 0.32 0.44 0.44 0.23 0.37 0.49 0.4 0.363333333 23 28 38 32.33333333 29.66666667 0.833909692 -0.135340423 GO:0016604///nuclear body GO:0003674///molecular_function "GO:0045893///positive regulation of transcription, DNA-templated" 403175 403175 'Tigd4' mRNA 26 27 16 0.41 0.42 0.27 0.12 0.17 0.16 0.366666667 0.15 9 12 11.02 23 10.67333333 0.089887223 -1.108942036 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding GO:0008150///biological_process 403178 403178 'Plcxd1' mRNA 313.82 350.55 281.58 5.23 5.72 4.98 2.13 2.99 2.52 5.31 2.546666667 148.04 203.75 168.16 315.3166667 173.3166667 1.11E-06 -0.869127339 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0008081///phosphoric diester hydrolase activity GO:0006629///lipid metabolic process 403180 403180 'Ccdc121' mRNA 7 13 13 0.22 0.41 0.44 0.06 0.11 0.34 0.356666667 0.17 2 4 12 11 6 0.412622832 -0.88619285 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 403183 403183 'Mettl21e' mRNA 0 0 1 0 0 0.02 0 0 0.05 0.006666667 0.016666667 0 0 3 0.333333333 1 0.749787559 1.475757224 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation 403185 403185 'Cfap97d2' mRNA 57 37 43 3.55 2.45 2.68 0.24 0.29 0.25 2.893333333 0.26 5 7 5 45.66666667 5.666666667 1.45E-07 -3.021200542 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 403187 403187 'Opa3' mRNA 1343 1448 1371 33.41 35.48 36.18 30.37 28.07 28.2 35.02333333 28.88 1404 1267 1262 1387.333333 1311 0.328570952 -0.094404652 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0007601///visual perception+++GO:0019216///regulation of lipid metabolic process+++GO:0040008///regulation of growth+++GO:0045444///fat cell differentiation+++GO:0050905///neuromuscular process+++GO:0060348///bone development+++GO:0070584///mitochondrion morphogenesis 403205 403205 'Agr3' mRNA 1994 2083 2150 181.72 195.15 207.76 163.49 165.99 157.1 194.8766667 162.1933333 2060 2061 1883 2075.666667 2001.333333 0.511544508 -0.066454307 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle GO:0002162///dystroglycan binding GO:0060548///negative regulation of cell death 403395 403395 'Clec3a' mRNA 6 10 9 0.11 0.18 0.18 0.21 0.1 0.1 0.156666667 0.136666667 13 6 6 8.333333333 8.333333333 0.992642964 -0.020494058 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0030246///carbohydrate binding GO:0001503///ossification 404238 404238 'Mrgprb3' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0043303///mast cell degranulation+++GO:0045576///mast cell activation 404289 404289 'Vmn1r181' mRNA 0 1 0 0 0.06 0 0.1 0.05 0.36 0.02 0.17 2 1 7 0.333333333 3.333333333 0.174697858 3.20719972 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone 404337 404337 'Olfr1383' mRNA 29.97 37.02 50.07 2.08 2.55 3.69 2.11 2.75 2.14 2.773333333 2.333333333 34.79 44.18 34.04 39.02 37.67 0.89745755 -0.069660236 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 404545 404545 'Ano7' mRNA 1 4 3 0.01 0.06 0.05 0.15 0.12 0.16 0.04 0.143333333 12 9 12 2.666666667 11 0.057681285 2.030231617 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity+++GO:0046983///protein dimerization activity GO:0006821///chloride transport+++GO:0006869///lipid transport+++GO:0055085///transmembrane transport+++GO:0061588///calcium activated phospholipid scrambling+++GO:0061589///calcium activated phosphatidylserine scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:1902476///chloride transmembrane transport 404634 404634 'Macroh2a2' mRNA 648.47 672.82 636.25 17.16 17.99 18.23 20.72 18.47 20.2 17.79333333 19.79666667 842.3 763.89 812.2 652.5133333 806.13 0.004213512 0.293172427 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0007420///brain development+++GO:0007549///dosage compensation+++GO:0031507///heterochromatin assembly+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0071169///establishment of protein localization to chromatin+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I" 404710 404710 'Iqgap3' mRNA 8 2 0 0.07 0.02 0 1.87 1.85 1.53 0.03 1.75 230 223 182 3.333333333 211.6666667 1.43E-30 5.980834881 04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0016328///lateral plasma membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0031267///small GTPase binding+++GO:0051015///actin filament binding+++GO:0070856///myosin VI light chain binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000187///activation of MAPK activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0008361///regulation of cell size+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0043087///regulation of GTPase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071310///cellular response to organic substance 406217 406217 'Bex4' mRNA 815.69 841.37 775.6 65.51 66.96 66.13 27.44 27.34 25.33 66.2 26.70333333 390.73 378.5 348.53 810.8866667 372.5866667 3.41E-26 -1.134462947 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0042826///histone deacetylase binding+++GO:0043014///alpha-tubulin binding GO:0007059///chromosome segregation+++GO:0007346///regulation of mitotic cell cycle+++GO:0030334///regulation of cell migration+++GO:0042127///regulation of cell proliferation+++GO:1904428///negative regulation of tubulin deacetylation 406218 406218 'Panx2' mRNA 121 109 90 1.74 1.47 1.39 0.59 0.44 0.47 1.533333333 0.5 47 33 39 106.6666667 39.66666667 1.70E-06 -1.43694504 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005243///gap junction channel activity+++GO:0015267///channel activity+++GO:0022829///wide pore channel activity+++GO:0044877///protein-containing complex binding+++GO:0055077///gap junction hemi-channel activity GO:0002931///response to ischemia+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0007267///cell-cell signaling+++GO:0032732///positive regulation of interleukin-1 production+++GO:0055085///transmembrane transport 406219 406219 'Krt87' mRNA 14 19 16 0.44 0.59 0.53 0.38 0.22 0.09 0.52 0.23 14 8 3 16.33333333 8.333333333 0.238848521 -0.988428855 GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 406220 406220 'Krt77' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0045095///keratin filament 406221 406221 'Krt40' mRNA 19 17 16 0.55 0.48 0.48 0.24 0.03 0.1 0.503333333 0.123333333 10 1 4 17.33333333 5 0.037411449 -1.815441666 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 407243 407243 'Tmem189' mRNA 408 339 289 13.93 11.41 10.47 17.09 16.9 17.66 11.93666667 17.21666667 575 555 575 345.3333333 568.3333333 9.94E-08 0.710822346 00565///Ether lipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity+++GO:0050207///plasmanylethanolamine desaturase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0008611///ether lipid biosynthetic process 407785 407785 'Ndufs6' mRNA 1672 1598 1563 277.91 265.59 275.84 256.64 284.39 280.73 273.1133333 273.92 1756 1888 1848 1611 1830.666667 0.038173444 0.173581972 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function "GO:0001822///kidney development+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0006631///fatty acid metabolic process+++GO:0006936///muscle contraction+++GO:0010259///multicellular organism aging+++GO:0022904///respiratory electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0035264///multicellular organism growth+++GO:0061458///reproductive system development+++GO:0070584///mitochondrion morphogenesis+++GO:0072359///circulatory system development" 407786 407786 'Taf9b' mRNA 737 778 806 16.21 16.89 18.81 19.14 16.34 17.45 17.30333333 17.64333333 998 831 883 773.6666667 904 0.066534583 0.209333943 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0033276///transcription factor TFTC complex GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0030307///positive regulation of cell growth+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization" 407788 407788 'BC051142' mRNA 110 76 109 2.8 1.85 2.59 0.58 0.52 0.6 2.413333333 0.566666667 29 23 27 98.33333333 26.33333333 1.97E-08 -1.919373745 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 407790 407790 'Ndufa4l2' mRNA 76 50 51 5.1 3.32 3.63 3.16 3.06 2.85 4.016666667 3.023333333 54 51 47 59 50.66666667 0.596394042 -0.229559842 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005751///mitochondrial respiratory chain complex IV GO:0008150///biological_process+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport 407795 407795 'Smim31' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon 407800 407800 'Ecm2' mRNA 163 187 202.01 2.49 2.86 3.24 1.78 1.4 1.69 2.863333333 1.623333333 136 104 119.78 184.0033333 119.9266667 0.003897358 -0.63792129 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0070052///collagen V binding GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization 407812 407812 'Zfp941' mRNA 131 164 155 1.81 2.23 2.27 0.29 0.45 0.38 2.103333333 0.373333333 24 37 31 150 30.66666667 1.82E-15 -2.300897484 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 407819 407819 'BC031181' mRNA 3323 3293 3238 207.34 203.67 215.41 189.93 194.37 188.86 208.8066667 191.0533333 3378 3375 3273 3284.666667 3342 0.874983121 0.012906313 GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet 407821 407821 'Znrf3' mRNA 1880 1913 1784 14.91 14.75 14.86 8.29 7.97 7.95 14.84 8.07 1206 1126 1105 1859 1145.666667 7.89E-22 -0.709979519 04310///Wnt signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0038018///Wnt receptor catabolic process+++GO:0060173///limb development+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0072089///stem cell proliferation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway" 407823 407823 'Baz2b' mRNA 2511.69 2591.01 2332.91 15.93 16.18 15.76 9.72 9.04 9.21 15.95666667 9.323333333 1780.01 1612.58 1623.61 2478.536667 1672.066667 9.78E-18 -0.579084174 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0090647///modulation of age-related behavioral decline 407831 407831 'Tmem204' mRNA 344 344 320 11.16 11 11.01 8.64 7.4 8.58 11.05666667 8.206666667 306 256 294 336 285.3333333 0.117407793 -0.247834212 GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005515///protein binding GO:0001945///lymph vessel development+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0051145///smooth muscle cell differentiation 408022 408022 'Primpol' mRNA 140.93 159.7 175.8 1.74 2.09 2.38 1.91 2.11 1.76 2.07 1.926666667 165.94 180.46 148.78 158.81 165.06 0.876586799 0.041807045 GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005694///chromosome+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003682///chromatin binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003896///DNA primase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding "GO:0006264///mitochondrial DNA replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0019985///translesion synthesis+++GO:0031297///replication fork processing+++GO:0032774///RNA biosynthetic process+++GO:0042276///error-prone translesion synthesis+++GO:0043504///mitochondrial DNA repair" 408058 408058 'BC048507' mRNA 0 2 0 0 0.26 0 0 0 0 0.086666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0008180///COP9 signalosome+++GO:0030141///secretory granule+++GO:0030286///dynein complex+++GO:0072686///mitotic spindle+++GO:1904115///axon cytoplasm GO:0019899///enzyme binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding+++GO:0097110///scaffold protein binding "GO:0007017///microtubule-based process+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042326///negative regulation of phosphorylation+++GO:0060271///cilium assembly+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed" 408059 408059 'BC049352' mRNA 7 5 2 0.21 0.14 0.07 0.21 0.25 0.31 0.14 0.256666667 11 10 10 4.666666667 10.33333333 0.26710108 1.147859016 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 408062 408062 'Zfp873' mRNA 759.88 798.99 727.14 8.17 8.52 8.67 4.16 4.28 4.72 8.453333333 4.386666667 411.67 406.57 437.8 762.0033333 418.68 2.68E-16 -0.875719022 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 408065 408065 'Zfp456' mRNA 88.7 76.43 79.39 1.17 0.99 1.11 1.06 1.33 1.38 1.09 1.256666667 91.87 113.53 116.42 81.50666667 107.2733333 0.182380106 0.387214156 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 408066 408066 'Cspg4b' mRNA 792 880 652 6.91 7.58 5.62 1.79 2.29 2.02 6.703333333 2.033333333 267 311 292 774.6666667 290 5.45E-29 -1.422875539 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 408067 408067 'Zfp874b' mRNA 367.98 388.93 384.29 4.9 5.21 5.39 2.82 2.58 2.51 5.166666667 2.636666667 241.84 220.09 213.29 380.4 225.0733333 1.62E-07 -0.770335555 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 408068 408068 'Zfp738' mRNA 251.25 308.99 241.83 2.99 3.62 3.06 2.83 2.38 2.69 3.223333333 2.633333333 273.64 224.2 251.68 267.3566667 249.84 0.610583174 -0.107088474 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 408191 408191 'Gm5415' mRNA 4.4 7 3 0.06 0.1 0.05 0.1 0.01 0.16 0.07 0.09 7.97 1 12.18 4.8 7.05 0.737037832 0.509975616 03013///Nucleocytoplasmic transport+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005829///cytosol GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016929///SUMO-specific protease activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization 408192 408192 'Gm9839' mRNA 2.81 0.94 1.93 0.12 0.04 0.08 0 0 0 0.08 0 0 0 0 1.893333333 0 0.60428608 -2.461629596 03013///Nucleocytoplasmic transport+++04310///Wnt signaling pathway GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity GO:0006508///proteolysis+++GO:0008150///biological_process 408193 408193 'Otud6a' mRNA 0 2 0 0 0.13 0 0 0.12 0.06 0.043333333 0.06 0 2 1 0.666666667 1 0.865347402 0.627343477 GO:0005575///cellular_component GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0035523///protein K29-linked deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:1990167///protein K27-linked deubiquitination+++GO:1990168///protein K33-linked deubiquitination 414069 414069 'BC024978' mRNA 636.47 727.55 865.41 6.33 7.02 8.66 4.69 4.8 4.77 7.336666667 4.753333333 580.03 581.99 574.12 743.1433333 578.7133333 0.007560434 -0.378896018 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 414077 414077 'Wdr83os' mRNA 1127 1034 903 115.28 105.04 98.03 116.7 127.11 123 106.1166667 122.27 1304 1382 1326 1021.333333 1337.333333 3.59E-05 0.380689786 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0044183///protein binding involved in protein folding GO:0006457///protein folding+++GO:0045048///protein insertion into ER membrane 414084 414084 'Tnip3' mRNA 1 2 5 0.01 0.03 0.08 0.72 0.83 0.57 0.04 0.706666667 58 65 44 2.666666667 55.66666667 1.49E-10 4.365088974 GO:0031593///polyubiquitin modification-dependent protein binding GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071222///cellular response to lipopolysaccharide 414089 414089 'Gja6' mRNA 0 1 1 0 0.03 0.03 0.02 0.05 0.1 0.02 0.056666667 1 2 4 0.666666667 2.333333333 0.475128737 1.793285295 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044291///cell-cell contact zone+++GO:0070160///tight junction GO:0005243///gap junction channel activity+++GO:0008013///beta-catenin binding+++GO:0015075///ion transmembrane transporter activity+++GO:0015631///tubulin binding+++GO:0043014///alpha-tubulin binding+++GO:0055077///gap junction hemi-channel activity+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0010644///cell communication by electrical coupling+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport 414758 414758 'Zfp950' mRNA 1950.49 1824.84 1749.25 19.9 17.85 18.55 12.27 12.42 11.8 18.76666667 12.16333333 1270.59 1198.89 1216.29 1841.526667 1228.59 2.26E-15 -0.595587453 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0001570///vasculogenesis+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006807///nitrogen compound metabolic process+++GO:0009791///post-embryonic development+++GO:0014909///smooth muscle cell migration+++GO:0030097///hemopoiesis+++GO:0035264///multicellular organism growth+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis" 414801 414801 'Itprip' mRNA 386 440 408 5.5 6.16 6.16 7.81 7.78 7.28 5.94 7.623333333 628 614 566 411.3333333 602.6666667 7.71E-06 0.539088613 GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding GO:0043086///negative regulation of catalytic activity+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 414872 414872 'Zyg11b' mRNA 806.64 789.2 730.58 4.11 3.81 3.8 3.18 3.69 3.13 3.906666667 3.333333333 743.25 802.51 712.16 775.4733333 752.64 0.699614808 -0.0528136 GO:0031462///Cul2-RING ubiquitin ligase complex GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 415115 415115 'Neurl2' mRNA 69.92 84.05 84.65 3.74 4.44 4.81 5.16 5.46 4.49 4.33 5.036666667 110.55 114.21 93.11 79.54 105.9566667 0.162100586 0.406027599 GO:0005737///cytoplasm+++GO:0005927///muscle tendon junction+++GO:0030891///VCB complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0030239///myofibril assembly+++GO:0035556///intracellular signal transduction+++GO:0045214///sarcomere organization 431706 431706 'Zfp457' mRNA 23.65 19 12.91 0.63 0.5 0.37 0.09 0.17 0.2 0.5 0.153333333 4 7 8.17 18.52 6.39 0.054027857 -1.505397516 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070895///negative regulation of transposon integration" 432442 432442 'Akap7' mRNA 381.07 409.61 330.23 5.94 6.68 5.03 6.52 6.11 6.43 5.883333333 6.353333333 390.68 385.07 416.23 373.6366667 397.3266667 0.641550165 0.080322901 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030315///T-tubule+++GO:0032991///protein-containing complex+++GO:0070382///exocytic vesicle+++GO:0098686///hippocampal mossy fiber to CA3 synapse GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0016208///AMP binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051018///protein kinase A binding GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0008104///protein localization+++GO:0010738///regulation of protein kinase A signaling+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060306///regulation of membrane repolarization+++GO:0071320///cellular response to cAMP+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1902261///positive regulation of delayed rectifier potassium channel activity 432450 432450 'Nkain2' mRNA 333.5 325 264.86 5.58 6.68 5.17 0.39 0.58 0.22 5.81 0.396666667 29.77 40.23 40.01 307.7866667 36.67 1.19E-42 -3.086683354 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002028///regulation of sodium ion transport 432467 432467 'Hnrnph3' mRNA 2250.53 2299.96 2101.16 86.74 86.84 87.35 60.96 59.76 63.86 86.97666667 61.52666667 1758.09 1716.07 1792.51 2217.216667 1755.556667 3.92E-07 -0.347317021 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0030855///epithelial cell differentiation+++GO:0043484///regulation of RNA splicing 432478 432478 'Tmprss9' mRNA 133 115 106 2.03 1.7 1.75 1.15 0.99 1.06 1.826666667 1.066666667 84 74 78 118 78.66666667 0.022339932 -0.595395687 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0031639///plasminogen activation 432479 432479 '4930404N11Rik' mRNA 5.83 6.7 7.01 0.6 0.69 0.77 0 0.21 0.1 0.686666667 0.103333333 0 2.28 1.12 6.513333333 1.133333333 0.104428866 -2.593397334 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 432486 432486 'Gnptab' mRNA 598 548 391 6.09 5.48 4.46 4.61 4.85 5.49 5.343333333 4.983333333 505 529 603 512.3333333 545.6666667 0.642977471 0.087273818 04142///Lysosome GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003976///UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0046872///metal ion binding" GO:0007040///lysosome organization+++GO:0009306///protein secretion+++GO:0016256///N-glycan processing to lysosome+++GO:0033299///secretion of lysosomal enzymes+++GO:0046835///carbohydrate phosphorylation 432502 432502 'Rpl6l' mRNA 17.8 16.02 18.28 1.22 1.09 1.33 0.57 0.55 0.18 1.213333333 0.433333333 9.59 8.93 2.83 17.36666667 7.116666667 0.078894524 -1.441740615 432508 432508 'Cpsf6' mRNA 1956 1965 1911 15.68 15.52 16.22 15.11 14.44 13.9 15.80666667 14.48333333 2166 2021 1931 1944 2039.333333 0.535059378 0.056472927 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005726///perichromatin fibrils+++GO:0005737///cytoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005849///mRNA cleavage factor complex+++GO:0016607///nuclear speck+++GO:0035061///interchromatin granule+++GO:0042382///paraspeckles+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0043023///ribosomal large subunit binding+++GO:1990448///exon-exon junction complex binding GO:0006397///mRNA processing+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0051262///protein tetramerization+++GO:0051290///protein heterotetramerization+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:0110104///mRNA alternative polyadenylation+++GO:1990120///messenger ribonucleoprotein complex assembly 432516 432516 'Myo1a' mRNA 15 18 21 0.24 0.29 0.36 0.2 0.14 0.07 0.296666667 0.136666667 14 10 5 18 9.666666667 0.231250553 -0.918343032 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016459///myosin complex+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0031982///vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0007605///sensory perception of sound+++GO:0030030///cell projection organization+++GO:0030033///microvillus assembly+++GO:0030050///vesicle transport along actin filament+++GO:0032880///regulation of protein localization+++GO:0051648///vesicle localization 432530 432530 'Adcy1' mRNA 647 606 647 2.74 2.52 2.91 1.07 1.02 0.94 2.723333333 1.01 291 272 247 633.3333333 270 1.59E-22 -1.244136752 "00230///Purine metabolism+++01522///Endocrine resistance+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04072///Phospholipase D signaling pathway+++04114///Oocyte meiosis+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04714///Thermogenesis+++04720///Long-term potentiation+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04913///Ovarian steroidogenesis+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04921///Oxytocin signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04976///Bile secretion+++05032///Morphine addiction+++05142///Chagas disease+++05146///Amoebiasis+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05414///Dilated cardiomyopathy" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0046872///metal ion binding GO:0006171///cAMP biosynthetic process+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0007616///long-term memory+++GO:0007623///circadian rhythm+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010226///response to lithium ion+++GO:0019933///cAMP-mediated signaling+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0042752///regulation of circadian rhythm+++GO:0048511///rhythmic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0071277///cellular response to calcium ion+++GO:0150076///neuroinflammatory response+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1904322///cellular response to forskolin+++GO:2000300///regulation of synaptic vesicle exocytosis 432552 432552 'Fam71b' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 432555 432555 'Gm5431' mRNA 44.32 33.75 33.44 0.82 0.61 0.66 4.12 4.15 3.57 0.696666667 3.946666667 256.42 251.97 215 37.17 241.13 9.33E-30 2.70384345 04668///TNF signaling pathway GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 432572 432572 'Specc1' mRNA 605 668 623 5.11 5.58 5.63 6.73 6.57 6.71 5.44 6.67 922 892 892 632 902 3.40E-07 0.501400724 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031941///filamentous actin+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell GO:0003674///molecular_function GO:0001824///blastocyst development+++GO:0008306///associative learning+++GO:0030036///actin cytoskeleton organization 432582 432582 'Ccdc92b' mRNA 38 52 9 0.52 0.69 0.13 0.21 0.04 0.07 0.446666667 0.106666667 18 3 6 33 9 0.014384771 -1.8717348 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 432589 432589 'Gm11541' mRNA 6 2 0 0.21 0.07 0 0.03 0.22 0.12 0.093333333 0.123333333 1 7 4 2.666666667 4 0.758811044 0.611709752 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 432611 432611 'Dnaic2' mRNA 2027 2184 2143 40.85 41.82 45.92 4.54 5.31 4.5 42.86333333 4.783333333 262 299 251 2118 270.6666667 7.11E-194 -2.980342343 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005858///axonemal dynein complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0009897///external side of plasma membrane+++GO:0030286///dynein complex+++GO:0036126///sperm flagellum+++GO:0036157///outer dynein arm+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0007368///determination of left/right symmetry+++GO:0030030///cell projection organization+++GO:0036158///outer dynein arm assembly+++GO:0060271///cilium assembly 432628 432628 'Mfsd2b' mRNA 53 45 45 0.93 0.78 0.85 0.43 0.42 0.42 0.853333333 0.423333333 28 26.91 27 47.66666667 27.30333333 0.048559358 -0.831535659 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity+++GO:0015293///symporter activity+++GO:0046624///sphingolipid transporter activity GO:0006869///lipid transport+++GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport+++GO:0071702///organic substance transport 432677 432677 'Vrtn' mRNA 2 5 2 0.04 0.09 0.04 0 0.02 0 0.056666667 0.006666667 0 1 0 3 0.333333333 0.199662503 -3.063819779 GO:0000785///chromatin GO:0006357///regulation of transcription by RNA polymerase II 432720 432720 'Akr1c19' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018636///phenanthrene 9,10-monooxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0032052///bile acid binding+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0045703///ketoreductase activity+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047042///androsterone dehydrogenase (B-specific) activity+++GO:0047086///ketosteroid monooxygenase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047743///chlordecone reductase activity+++GO:0047787///delta4-3-oxosteroid 5beta-reductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0008202///steroid metabolic process 432725 432725 'Gm5445' mRNA 0.98 0 0 0.18 0 0 0 0 0 0.06 0 0 0 0 0.326666667 0 432731 432731 'Zscan26' mRNA 3739 3553.73 3964.44 49.44 46.3 55.84 36.24 34.85 37.12 50.52666667 36.07 3154.04 2947.91 3136.22 3752.39 3079.39 1.50E-04 -0.300658206 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 432763 432763 'Prr7' mRNA 8 10 2 0.35 0.44 0.09 0 0.12 0.16 0.293333333 0.093333333 0 3 4 6.666666667 2.333333333 0.317540838 -1.491651922 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0036041///long-chain fatty acid binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:1990782///protein tyrosine kinase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0010942///positive regulation of cell death+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033077///T cell differentiation in thymus+++GO:0043065///positive regulation of apoptotic process+++GO:0046632///alpha-beta T cell differentiation+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 432769 432769 'Zfp708' mRNA 81.07 91.54 97.78 1.83 2.04 2.38 1.35 0.92 1.31 2.083333333 1.193333333 69.03 45.67 63.31 90.13 59.33666667 0.050138836 -0.621341821 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 432770 432770 'Rslcan18' mRNA 43 34 38 0.79 0.62 0.74 0.75 0.73 0.46 0.716666667 0.646666667 46.63 44.6 28 38.33333333 39.74333333 0.969519197 0.023340842 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 432779 432779 'Lrrc14b' mRNA 64.9 48.21 55.65 1.31 0.96 1.19 1.22 1.2 1.22 1.153333333 1.213333333 69.53 66.75 67.27 56.25333333 67.85 0.493035609 0.261602059 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 432800 432800 'Gm5454' mRNA 6.45 13.06 8.21 0.15 0.3 0.2 0.1 0 0.1 0.216666667 0.066666667 5.07 0 4.72 9.24 3.263333333 0.195919566 -1.601261132 432825 432825 'Gm5458' mRNA 4.79 4.94 1.23 0.2 0.24 0.04 0.17 0.04 0.07 0.16 0.093333333 4.49 1.41 2.28 3.653333333 2.726666667 0.863090843 -0.363874379 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 432839 432839 'Gprin2' mRNA 48 47 55 0.23 0.35 0.45 0.21 0.26 0.22 0.343333333 0.23 51 31 38 50 40 0.449269273 -0.341305884 GO:0005886///plasma membrane GO:0003674///molecular_function GO:0031175///neuron projection development 432867 432867 'Defb48' mRNA 0 0 3 0 0 0.66 0 0 0 0.22 0 0 0 0 1 0 0.625198426 -2.527571966 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0031731///CCR6 chemokine receptor binding+++GO:0042056///chemoattractant activity GO:0006952///defense response+++GO:0008150///biological_process+++GO:0042742///defense response to bacterium+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis 432879 432879 'Kbtbd6' mRNA 6.48 10.25 7.01 0.12 0.19 0.14 0.52 0.28 0.28 0.15 0.36 32.62 16.88 16.78 7.913333333 22.09333333 0.043766865 1.460859764 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0035020///regulation of Rac protein signal transduction+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination 432940 432940 'Otulin' mRNA 59 75 68 2.34 2.95 2.83 4.14 4.6 4.64 2.706666667 4.46 120 130 130 67.33333333 126.6666667 4.98E-04 0.900664321 GO:0005737///cytoplasm+++GO:0071797///LUBAC complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response+++GO:0050728///negative regulation of inflammatory response+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:1990108///protein linear deubiquitination 432964 432964 'Iqank1' mRNA 71 85 50 2.17 2.59 1.66 0.21 0.95 0.64 2.14 0.6 10 36 23 68.66666667 23 5.51E-04 -1.572011782 GO:0003674///molecular_function GO:0008150///biological_process 432995 432995 'Smim22' mRNA 281 227 279 65.58 53.66 68.05 30.62 34.39 36.61 62.43 33.87333333 140 163 175 262.3333333 159.3333333 1.63E-04 -0.733148188 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0030335///positive regulation of cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042127///regulation of cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0140042///lipid droplet formation 432999 432999 'A930007A09Rik' mRNA 84 68 122 1.14 0.91 1.76 1.26 1.29 1.35 1.27 1.3 107 107 111 91.33333333 108.3333333 0.528576738 0.222661597 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 433016 433016 'Cstdc4' mRNA 10 7 9 2.36 1.67 2.26 1.67 3.24 3.48 2.096666667 2.796666667 8 15 16 8.666666667 13 0.532590658 0.575866714 GO:0001533///cornified envelope+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0002020///protease binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0045861///negative regulation of proteolysis+++GO:0098609///cell-cell adhesion 433022 433022 'Plcxd2' mRNA 818 774 654 5.88 5.47 4.99 1.74 1.69 1.53 5.446666667 1.653333333 279 265 238 748.6666667 260.6666667 6.65E-36 -1.530960904 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0016042///lipid catabolic process 433064 433064 'Gm17748' mRNA 3.87 11.9 3.62 0.48 1.45 0.47 0.61 0.4 0.82 0.8 0.61 5.69 3.6 7.38 6.463333333 5.556666667 0.900799631 -0.176070126 433091 433091 'Pnpla1' mRNA 32.85 30.96 23.61 0.39 0.36 0.3 0.2 0.17 0.19 0.35 0.186666667 19 16.05 18.08 29.14 17.71 0.224357589 -0.689165887 GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane "GO:0004806///triglyceride lipase activity+++GO:0016740///transferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016787///hydrolase activity+++GO:0030280///structural constituent of epidermis" GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0030216///keratinocyte differentiation+++GO:0046513///ceramide biosynthetic process+++GO:0055088///lipid homeostasis+++GO:0061436///establishment of skin barrier 433099 433099 'Ly6g6f' mRNA 0 1.27 1 0 0.07 0.06 0.24 0.16 0 0.043333333 0.133333333 4.67 3.09 0 0.756666667 2.586666667 0.509773941 1.77996318 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 433182 433182 'Eno1b' mRNA 4094.28 4233.35 4070.11 134.63 137.2 141.98 161.5 175.48 163.6 137.9366667 166.86 5644.78 5986.3 5533.45 4132.58 5721.51 3.66E-13 0.457929385 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway GO:0000015///phosphopyruvate hydratase complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0045121///membrane raft+++GO:0097060///synaptic membrane+++GO:0099738///cell cortex region "GO:0000287///magnesium ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0004634///phosphopyruvate hydratase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0019899///enzyme binding+++GO:0031072///heat shock protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006096///glycolytic process+++GO:0010756///positive regulation of plasminogen activation+++GO:0030308///negative regulation of cell growth+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045933///positive regulation of muscle contraction+++GO:0051099///positive regulation of binding+++GO:0061621///canonical glycolysis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071456///cellular response to hypoxia+++GO:0098761///cellular response to interleukin-7+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:2001171///positive regulation of ATP biosynthetic process" 433215 433215 'Tmem262' mRNA 6 10 11 0.12 0.2 0.38 0.13 0.13 0.13 0.233333333 0.13 7 4 2 9 4.333333333 0.338561597 -1.078744553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 433256 433256 'Acsl5' mRNA 717 731 726 14.05 14.24 15.19 34.24 35.4 33.63 14.49333333 34.42333333 1974 2014 1909 724.6666667 1965.666667 3.75E-69 1.427609202 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome+++04216///Ferroptosis+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0047676///arachidonate-CoA ligase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010747///positive regulation of plasma membrane long-chain fatty acid transport+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0015908///fatty acid transport+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 433294 433294 'Mettl21c' mRNA 0 1 3 0 0.06 0.18 0 0 0.05 0.08 0.016666667 0 0 1 1.333333333 0.333333333 0.593573285 -1.948783805 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0031072///heat shock protein binding GO:0006479///protein methylation+++GO:0007519///skeletal muscle tissue development+++GO:0008628///hormone-mediated apoptotic signaling pathway+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation+++GO:0071549///cellular response to dexamethasone stimulus 433319 433319 'Gm5528' mRNA 0 1.01 0 0 0.17 0 0.31 0 0 0.056666667 0.103333333 2.1 0 0 0.336666667 0.7 0.863090843 0.855208319 433323 433323 'Sgpp2' mRNA 368.16 381.95 352.07 4.94 5.06 5.03 1.65 1.32 1.54 5.01 1.503333333 144.37 110.19 128.44 367.3933333 127.6666667 5.66E-21 -1.539838018 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0070780///dihydrosphingosine-1-phosphate phosphatase activity GO:0006670///sphingosine metabolic process+++GO:0046839///phospholipid dephosphorylation+++GO:0046849///bone remodeling+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0065003///protein-containing complex assembly 433365 433365 'Teddm1b' mRNA 18.16 22.14 10.13 0.4 0.48 0.24 0.87 0.84 0.72 0.373333333 0.81 45.41 42.83 36.35 16.81 41.53 0.008878398 1.296707333 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 433375 433375 'Creg1' mRNA 1945 2147 2008 51.06 55.52 55.92 76.49 81.97 74.65 54.16666667 77.70333333 3350 3505 3165 2033.333333 3340 3.08E-22 0.704591396 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005667///transcription factor complex GO:0008134///transcription factor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0040008///regulation of growth" 433415 433415 'Gm13420' mRNA 1434 1420 1337 17.18 17.51 17.12 1.52 1.35 1.49 17.27 1.453333333 151 125 131 1397 135.6666667 3.31E-192 -3.376223292 GO:0016020///membrane+++GO:0016021///integral component of membrane 433416 433416 'Gm13547' mRNA 46.28 58.71 42.91 0.59 0.57 0.45 0.2 0.17 0.37 0.536666667 0.246666667 23.48 19.61 42.14 49.3 28.41 0.084213586 -0.804257822 GO:0005575///cellular_component+++GO:0005794///Golgi apparatus GO:0003674///molecular_function GO:0008150///biological_process 433449 433449 'Olfr1197' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 433466 433466 'Jmjd7' mRNA 247 221 204 10.69 9.44 9.37 9.72 7.88 7.05 9.833333333 8.216666667 258 204 181 224 214.3333333 0.761096634 -0.075876509 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0004175///endopeptidase activity+++GO:0004177///aminopeptidase activity+++GO:0004497///monooxygenase activity+++GO:0008233///peptidase activity+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0016787///hydrolase activity+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding" GO:0006508///proteolysis+++GO:0018126///protein hydroxylation 433470 433470 'AA467197' mRNA 24 17 19 2.78 1.96 2.34 32.59 40.61 34.01 2.36 35.73666667 321 389 323 20 344.3333333 1.99E-56 4.096420382 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0009617///response to bacterium+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport 433485 433485 'Syndig1' mRNA 4 5 12 0.11 0.13 0.35 0.15 0.44 0.47 0.196666667 0.353333333 6 18 19 7 14.33333333 0.287570646 1.009954637 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098839///postsynaptic density membrane GO:0035254///glutamate receptor binding+++GO:0042803///protein homodimerization activity GO:0006886///intracellular protein transport+++GO:0051965///positive regulation of synapse assembly+++GO:0097091///synaptic vesicle clustering 433586 433586 'Maml3' mRNA 345 376 339 2.81 3 2.92 1.68 1.42 2.25 2.91 1.783333333 238 196 309 353.3333333 247.6666667 0.003639571 -0.524015475 04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0003713///transcription coactivator activity GO:0007219///Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0045944///positive regulation of transcription by RNA polymerase II 433632 433632 'Gm5544' mRNA 1 0 3 0.07 0 0.24 0.06 0.07 0 0.103333333 0.043333333 1 1 0 1.333333333 0.666666667 0.754095254 -1.057432323 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 433638 433638 'I830077J02Rik' mRNA 17 23 16 0.42 0.44 0.47 3.57 3.17 3.76 0.443333333 3.5 133 134 155 18.66666667 140.6666667 5.44E-20 2.905669076 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 433653 433653 'Gimd1' mRNA 1.94 2 0 0.03 0.03 0 0.04 0 0 0.02 0.013333333 3 0 0 1.313333333 1 0.999123543 -0.00436044 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0008150///biological_process 433667 433667 'Ankrd13c' mRNA 1194.09 1207.87 716.33 14.64 14.56 9.21 9.24 12.64 11.58 12.80333333 11.15333333 864.89 1155.11 1051.51 1039.43 1023.836667 0.958801825 -0.019069484 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding GO:0006621///protein retention in ER lumen+++GO:0010469///regulation of signaling receptor activity+++GO:2000209///regulation of anoikis 433693 433693 'Akirin2' mRNA 470.78 435 446.75 17.31 15.93 17.57 22.59 20.04 25.55 16.93666667 22.72666667 689.69 599 757 450.8433333 681.8966667 2.19E-06 0.585118737 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002376///immune system process+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010629///negative regulation of gene expression+++GO:0010950///positive regulation of endopeptidase activity+++GO:0032496///response to lipopolysaccharide+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 433698 433698 'Fam205a1' mRNA 52.94 38.71 28.16 0.43 0.31 0.24 0.44 0.36 0.46 0.326666667 0.42 62.96 49.41 63.74 39.93666667 58.70333333 0.175224561 0.554177468 GO:0016020///membrane+++GO:0016021///integral component of membrane 433700 433700 'Spag8' mRNA 860 876 899 32.21 33.37 35.27 3.4 3.31 3.03 33.61666667 3.246666667 98 101 85 878.3333333 94.66666667 2.67E-116 -3.227316844 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0030154///cell differentiation+++GO:0032092///positive regulation of protein binding+++GO:0045944///positive regulation of transcription by RNA polymerase II 433702 433702 'Ncbp1' mRNA 877.64 842.71 935.89 15.77 14.83 17.75 17.79 15.96 15.58 16.11666667 16.44333333 1141.74 1006.97 968.87 885.4133333 1039.193333 0.053842702 0.215235617 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005845///mRNA cap binding complex+++GO:0005846///nuclear cap binding complex+++GO:0034518///RNA cap binding complex+++GO:1990904///ribonucleoprotein complex GO:0000339///RNA cap binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000245///spliceosomal complex assembly+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0006401///RNA catabolic process+++GO:0006406///mRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0030307///positive regulation of cell growth+++GO:0031047///gene silencing by RNA+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0050684///regulation of mRNA processing+++GO:0051028///mRNA transport+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:1900363///regulation of mRNA polyadenylation+++GO:1905216///positive regulation of RNA binding" 433742 433742 'Gm12722' mRNA 13 6 10 1.78 0.82 1.45 0 0 0 1.35 0 0 0 0 9.666666667 0 5.67E-04 -5.731796273 433745 433745 'Gm12816' mRNA 91.2 117.85 90 4.3 5.49 4.51 4.78 4.78 5.31 4.766666667 4.956666667 116.27 113.52 124.85 99.68333333 118.2133333 0.406568231 0.235656169 433748 433748 'Llph-ps1' mRNA 0 1.14 0 0 0.11 0 0.09 0 0 0.036666667 0.03 1.13 0 0 0.38 0.376666667 0.998591786 -0.011756601 433752 433752 'Frg2f1' mRNA 49 66 75 1.47 1.95 2.39 1.88 1.63 1.32 1.936666667 1.61 72 61 49 63.33333333 60.66666667 0.863090843 -0.08142067 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 433759 433759 'Hdac1' mRNA 2153 2254 1976 62.29 64.25 60.65 66.94 65.12 65.84 62.39666667 65.96666667 2660 2526 2532 2127.666667 2572.666667 6.39E-05 0.263697119 04110///Cell cycle+++04213///Longevity regulating pathway - multiple species+++04330///Notch signaling pathway+++04613///Neutrophil extracellular trap formation+++04919///Thyroid hormone signaling pathway+++05016///Huntington disease+++05031///Amphetamine addiction+++05034///Alcoholism+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05203///Viral carcinogenesis+++05206///MicroRNAs in cancer+++05220///Chronic myeloid leukemia GO:0000118///histone deacetylase complex+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016580///Sin3 complex+++GO:0016581///NuRD complex+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0019899///enzyme binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0033613///activating transcription factor binding+++GO:0035851///Krueppel-associated box domain binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051059///NF-kappaB binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001975///response to amphetamine+++GO:0006325///chromatin organization+++GO:0006346///methylation-dependent chromatin silencing+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006476///protein deacetylation+++GO:0007492///endoderm development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0009913///epidermal cell differentiation+++GO:0010629///negative regulation of gene expression+++GO:0016575///histone deacetylation+++GO:0021766///hippocampus development+++GO:0030182///neuron differentiation+++GO:0031000///response to caffeine+++GO:0032496///response to lipopolysaccharide+++GO:0032732///positive regulation of interleukin-1 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032922///circadian regulation of gene expression+++GO:0034599///cellular response to oxidative stress+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042493///response to drug+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043922///negative regulation by host of viral transcription+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0048511///rhythmic process+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0052548///regulation of endopeptidase activity+++GO:0055093///response to hyperoxia+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0060789///hair follicle placode formation+++GO:0061029///eyelid development in camera-type eye+++GO:0061198///fungiform papilla formation+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000273///positive regulation of signaling receptor activity+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process+++GO:2000757///negative regulation of peptidyl-lysine acetylation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 433766 433766 'Trim63' mRNA 39 39 19 1.19 1.17 0.61 0.56 1.14 0.87 0.99 0.856666667 21 42 32 32.33333333 31.66666667 0.975146162 -0.023691045 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0043292///contractile fiber GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031432///titin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006513///protein monoubiquitination+++GO:0006936///muscle contraction+++GO:0010468///regulation of gene expression+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0014732///skeletal muscle atrophy+++GO:0014878///response to electrical stimulus involved in regulation of muscle adaptation+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051384///response to glucocorticoid+++GO:0070555///response to interleukin-1+++GO:0071549///cellular response to dexamethasone stimulus 433771 433771 'Micos10' mRNA 1789 1835 1982 39.04 39.42 45.88 45.3 50.37 49.54 41.44666667 48.40333333 2388 2593 2528 1868.666667 2503 2.91E-06 0.407838808 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0061617///MICOS complex GO:0003674///molecular_function GO:0008150///biological_process 433791 433791 'Zfp992' mRNA 134.85 163.62 147.8 1.98 2.36 2.3 2.29 2.25 1.96 2.213333333 2.166666667 179.61 172 148.58 148.7566667 166.73 0.53526958 0.15636025 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 433801 433801 'Gm13212' mRNA 36.64 37.39 39.82 0.67 0.69 0.78 2.49 2.21 2.3 0.713333333 2.333333333 148.79 139.29 131.88 37.95 139.9866667 3.41E-12 1.886619793 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 433804 433804 'Zfp985' mRNA 1.17 3 3 0.02 0.06 0.07 0.05 0.04 0.02 0.05 0.036666667 3 2 1 2.39 2 0.905938796 -0.245790308 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 433809 433809 'Rnf207' mRNA 18 19 21 0.41 0.42 0.47 0.33 0.3 0.47 0.433333333 0.366666667 16 16 19 19.33333333 17 0.797324406 -0.199901825 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0008270///zinc ion binding+++GO:0030544///Hsp70 protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0010628///positive regulation of gene expression+++GO:0055117///regulation of cardiac muscle contraction+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:1901207///regulation of heart looping+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:1903762///positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:1903954///positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 433813 433813 'Pusl1' mRNA 204.68 170.31 176.56 9.88 8.01 8.98 10.48 11.42 10.98 8.956666667 10.96 252.23 266.52 251.38 183.85 256.71 0.00843353 0.472485058 GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0031119///tRNA pseudouridine synthesis 433864 433864 'Nom1' mRNA 725.87 741.88 714.05 10.86 10.88 11.42 11.14 11.59 11.52 11.05333333 11.41666667 852.56 872.12 857.15 727.2666667 860.61 0.022306696 0.232145499 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003723///RNA binding GO:0042274///ribosomal small subunit biogenesis+++GO:0048820///hair follicle maturation 433874 433874 'Gm5553' mRNA 0 1 3 0 0.12 0.39 0 0 0 0.17 0 0 0 0 1.333333333 0 0.46613582 -2.912676135 433899 433899 'Grxcr1' mRNA 384 383 369 22.56 22.24 23 2.61 3.05 2.65 22.6 2.77 51 58 50 378.6666667 53 1.09E-50 -2.848074731 GO:0005829///cytosol+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0060091///kinocilium GO:0003674///molecular_function+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0097573///glutathione oxidoreductase activity GO:0007605///sensory perception of sound+++GO:0010923///negative regulation of phosphatase activity+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0048839///inner ear development+++GO:0060118///vestibular receptor cell development+++GO:0060119///inner ear receptor cell development+++GO:0060122///inner ear receptor cell stereocilium organization 433904 433904 'Ociad2' mRNA 1910.36 2061.97 2043.95 42.4 45.07 48.12 41.37 39.83 38.98 45.19666667 40.06 2143.23 2015.22 1955.57 2005.426667 2038.006667 0.924287695 0.009964293 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005768///endosome GO:0003674///molecular_function GO:0009617///response to bacterium 433926 433926 'Lrrc8b' mRNA 1028 1013 672 8.02 7.77 5.6 5.2 4.05 5.04 7.13 4.763333333 764 583 717 904.3333333 688 0.005042058 -0.399674189 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034702///ion channel complex GO:0005225///volume-sensitive anion channel activity GO:0006811///ion transport+++GO:0015698///inorganic anion transport+++GO:0098656///anion transmembrane transport 433931 433931 'Pigg' mRNA 618 623 588 7.79 7.68 7.83 4.07 4.67 4.4 7.766666667 4.38 364 416 365 609.6666667 381.6666667 1.54E-08 -0.685958888 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0051267///CP2 mannose-ethanolamine phosphotransferase activity+++GO:0051377///mannose-ethanolamine phosphotransferase activity GO:0006506///GPI anchor biosynthetic process 433938 433938 'Mn1' mRNA 950 993 822 7.33 7.54 6.73 1.92 1.58 1.63 7.2 1.71 287 230 236 921.6666667 251 3.10E-58 -1.88674869 GO:0005634///nucleus "GO:0001957///intramembranous ossification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0070564///positive regulation of vitamin D receptor signaling pathway+++GO:1902806///regulation of cell cycle G1/S phase transition" 433940 433940 'Fam222a' mRNA 128 161 65 2.61 3.26 1.38 0.59 0.68 0.72 2.416666667 0.663333333 33 37 39 118 36.33333333 9.72E-07 -1.693914672 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 433956 433956 'Dnaaf5' mRNA 810.5 713.76 739 13.99 11.86 13.46 8.82 8.53 9.32 13.10333333 8.89 592 575 604.68 754.42 590.56 9.14E-04 -0.365275013 GO:0005737///cytoplasm+++GO:0031514///motile cilium GO:0045505///dynein intermediate chain binding GO:0003341///cilium movement+++GO:0030030///cell projection organization+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly 433961 433961 'Gm5565' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 434008 434008 'Tmem178b' mRNA 513 538 449 2.39 2.43 2.16 0.24 0.2 0.23 2.326666667 0.223333333 63 50 56 500 56.33333333 7.06E-72 -3.159722695 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 434128 434128 'Pnmal2' mRNA 2007 2060 1476 26.08 26.32 20.34 21.95 19.74 20.88 24.24666667 20.85666667 1945 1708 1792 1847.666667 1815 0.815238082 -0.031903173 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434130 434130 'Ccdc8' mRNA 259 280 176 3.89 4.14 2.8 2.09 1.59 2.2 3.61 1.96 160 119 163 238.3333333 147.3333333 0.001101578 -0.698874403 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:1990393///3M complex GO:0000226///microtubule cytoskeleton organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0010923///negative regulation of phosphatase activity 434156 434156 'Eid2b' mRNA 267 291 285 6.15 6.6 6.97 4.89 5.5 5.88 6.573333333 5.423333333 244 268 284 281 265.3333333 0.647708549 -0.094331748 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding "GO:0045662///negative regulation of myoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 434175 434175 'Ccnb1-ps' mRNA 7.39 12.25 10.81 0.28 0.46 0.44 0.32 0.23 0.35 0.393333333 0.3 9.61 6.67 10.03 10.15 8.77 0.846914274 -0.228087308 434178 434178 'Zfp141' mRNA 395.5 368.87 331.31 5.24 4.79 4.66 2.89 3.15 3.92 4.896666667 3.32 250.72 265 330.77 365.2266667 282.1633333 0.02103863 -0.381128595 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 434179 434179 'Zfp975' mRNA 283.47 345.37 324.65 4.95 5.94 6.01 3.86 2.87 3.93 5.633333333 3.553333333 254.86 184.43 250.77 317.83 230.02 0.007217489 -0.483259715 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 434197 434197 'Fam169b' mRNA 18.24 24.03 20.08 0.36 0.51 0.46 0.27 0.44 0.56 0.443333333 0.423333333 15.01 24.06 31.06 20.78333333 23.37666667 0.825388239 0.168635182 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434203 434203 'Slc28a1' mRNA 2 1 1 0.04 0.02 0.02 0 0.05 0.05 0.026666667 0.033333333 0 3 3 1.333333333 2 0.828240694 0.591415608 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016607///nuclear speck+++GO:0031526///brush border membrane GO:0005337///nucleoside transmembrane transporter activity+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0015212///cytidine transmembrane transporter activity+++GO:0015213///uridine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015389///pyrimidine- and adenine-specific:sodium symporter activity+++GO:1901474///azole transmembrane transporter activity GO:0015855///pyrimidine nucleobase transport+++GO:0015861///cytidine transport+++GO:0015862///uridine transport+++GO:0045117///azole transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1901642///nucleoside transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport 434204 434204 'Whamm' mRNA 109 89 73 2.09 1.73 1.51 1.68 1.71 2.08 1.776666667 1.823333333 108 101 124 90.33333333 111 0.328861122 0.290125149 04530///Tight junction GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003779///actin binding+++GO:0008017///microtubule binding+++GO:0031267///small GTPase binding+++GO:0071933///Arp2/3 complex binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007015///actin filament organization+++GO:0007050///cell cycle arrest+++GO:0030032///lamellipodium assembly+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0048041///focal adhesion assembly+++GO:0051127///positive regulation of actin nucleation+++GO:0090527///actin filament reorganization+++GO:0097320///plasma membrane tubulation 434215 434215 'Lrrc32' mRNA 149 110 87 2.05 1.49 1.27 2.52 2.68 2.35 1.603333333 2.516666667 211 219 191 115.3333333 207 1.71E-04 0.838286235 GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0019838///growth factor binding+++GO:0050431///transforming growth factor beta binding GO:0001818///negative regulation of cytokine production+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0062009///secondary palate development+++GO:1901388///regulation of transforming growth factor beta activation+++GO:1901398///regulation of transforming growth factor beta3 activation 434218 434218 'Trim34b' mRNA 240.91 261.48 216.6 4.29 4.7 3.99 4.47 5.45 5.53 4.326666667 5.15 244.23 292.82 306.05 239.6633333 281.0333333 0.235013283 0.224561061 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 434219 434219 'Trim30c' mRNA 6 12 9 0.19 0.37 0.18 2.31 2.61 2.33 0.246666667 2.416666667 144 158 151 9 151 6.19E-27 4.058919935 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 434223 434223 'Gvin3' mRNA 73.95 82.07 57.06 0.44 0.49 0.37 2.15 1.83 2.28 0.433333333 2.086666667 413.72 345.23 422.51 71.02666667 393.82 2.53E-40 2.468109022 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434232 434232 'Iqck' mRNA 883.84 865.76 836.79 34.67 33.87 34.86 9.66 9.75 9.9 34.46666667 9.77 282.04 276.36 280.02 862.13 279.4733333 1.61E-50 -1.636248102 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434233 434233 'Ppp1ccb' mRNA 36.02 25.49 23.64 1.45 1.01 1.01 1.36 1.93 1.27 1.156666667 1.52 38.68 53.6 35.14 28.38333333 42.47333333 0.233049608 0.579430615 03015///mRNA surveillance pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++04720///Long-term potentiation+++04728///Dopaminergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04921///Oxytocin signaling pathway+++04931///Insulin resistance+++05031///Amphetamine addiction+++05034///Alcoholism+++05168///Herpes simplex virus 1 infection+++05205///Proteoglycans in cancer+++05415///Diabetic cardiomyopathy "GO:0000164///protein phosphatase type 1 complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0043197///dendritic spine+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse" GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0008022///protein C-terminus binding+++GO:0008157///protein phosphatase 1 binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0048511///rhythmic process+++GO:0051301///cell division+++GO:0060252///positive regulation of glial cell proliferation 434234 434234 'Rexo5' mRNA 782.55 765.53 720.95 5.82 5.73 6.74 3.15 2.55 2.89 6.096666667 2.863333333 487.19 407.81 493.72 756.3433333 462.9066667 1.04E-10 -0.720828913 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004527///exonuclease activity GO:0090305///nucleic acid phosphodiester bond hydrolysis 434246 434246 'Trim72' mRNA 8 4 4 0.18 0.07 0.08 0.04 0.07 0.03 0.11 0.046666667 2 3 2 5.333333333 2.333333333 0.417164981 -1.196743469 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042383///sarcolemma GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001778///plasma membrane repair+++GO:0003012///muscle system process+++GO:0006887///exocytosis+++GO:0006900///vesicle budding from membrane+++GO:0007517///muscle organ development+++GO:0010832///negative regulation of myotube differentiation+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0051260///protein homooligomerization 434325 434325 'Tmem221' mRNA 1321 1456 1448 51.29 55.76 59.68 27.5 29.4 26.2 55.57666667 27.7 813 849 754 1408.333333 805.3333333 8.32E-18 -0.819363233 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 434341 434341 'Nlrc5' mRNA 230 230 164 1.63 1.58 1.2 4 3.48 3.83 1.47 3.77 662 552 607 208 607 9.62E-28 1.537421032 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005524///ATP binding GO:0002376///immune system process+++GO:0009617///response to bacterium+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0035556///intracellular signal transduction+++GO:0043549///regulation of kinase activity+++GO:0045087///innate immune response+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway 434377 434377 'Zfp560' mRNA 262 252 217 3.16 3.1 2.92 1.73 1.94 2.06 3.06 1.91 154 164 175 243.6666667 164.3333333 0.001453686 -0.576569288 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 434402 434402 'Gm5617' mRNA 340 325 332 40.05 38.08 41.51 32.29 38.09 34.24 39.88 34.87333333 313 359 320 332.3333333 330.6666667 0.924287695 -0.018604952 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0008150///biological_process 434423 434423 'Dppa5a' mRNA 0 0 1 0 0 0.12 0 0 0.11 0.04 0.036666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression 434436 434436 'Lsmem2' mRNA 8.96 11.35 5.6 0.26 0.33 0.18 0.23 0.15 0.09 0.256666667 0.156666667 9.04 5.65 3.42 8.636666667 6.036666667 0.688410377 -0.50325808 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 434437 434437 'Amt' mRNA 609 557 669 21.99 19.75 26.42 17.57 15.84 14.72 22.72 16.04333333 552.01 482 455 611.6666667 496.3366667 0.021882648 -0.318845704 "00260///Glycine, serine and threonine metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00670///One carbon pool by folate+++01200///Carbon metabolism" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0004047///aminomethyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity GO:0006546///glycine catabolic process+++GO:0019464///glycine decarboxylation via glycine cleavage system+++GO:0032259///methylation 434438 434438 'Iho1' mRNA 0 4 4 0 0.08 0.08 0.02 0 0.07 0.053333333 0.03 1 0 4 2.666666667 1.666666667 0.781965445 -0.703362907 GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome GO:0005515///protein binding GO:0006310///DNA recombination+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0042138///meiotic DNA double-strand break formation+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:0060629///regulation of homologous chromosome segregation 434484 434484 'Sp140' mRNA 48.52 62.55 42.18 1.1 1.38 0.94 9.11 8.72 8.34 1.14 8.723333333 475.25 448.09 426.62 51.08333333 449.9866667 1.02E-62 3.140953735 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003677///DNA binding+++GO:0046872///metal ion binding 434540 434540 'Psg20' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0008150///biological_process 434624 434624 'Ftl1-ps2' mRNA 114.36 115.32 126.96 7.93 7.92 9.35 17.49 17.16 15.32 8.4 16.65666667 288.92 276.15 244.53 118.88 269.8666667 2.40E-10 1.172144008 434674 434674 'Slc22a28' mRNA 0 2 1 0 0.06 0.04 0.02 0 0 0.033333333 0.006666667 0.8 0 0 1 0.266666667 0.607488248 -2.448949589 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0015301///anion:anion antiporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015636///short-chain fatty acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015711///organic anion transport+++GO:0015912///short-chain fatty acid transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport 434689 434689 'Gm10220' mRNA 88.86 80.52 87.71 1.64 1.46 1.71 0.02 0 0.05 1.603333333 0.023333333 1.48 0 3.13 85.69666667 1.536666667 2.08E-13 -6.008509375 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434693 434693 'Mrto4-ps2' mRNA 180.29 168.02 152.38 1.45 1.33 1.3 1.12 0.76 0.75 1.36 0.876666667 161.15 107.12 104.13 166.8966667 124.1333333 0.07032808 -0.440145896 434756 434756 'Akap14' mRNA 152 136 152 4.89 4.31 5.19 0.39 0.32 0.58 4.796666667 0.43 14 11 20 146.6666667 15 5.73E-23 -3.304037777 GO:0005930///axoneme+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0035686///sperm fibrous sheath GO:0016301///kinase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051018///protein kinase A binding GO:0008150///biological_process+++GO:0016310///phosphorylation 434768 434768 'Rhox8' mRNA 14 11.66 4 0.71 0.59 0.22 0.44 0.49 0.45 0.506666667 0.46 10 10.82 9.86 9.886666667 10.22666667 0.998591786 0.004705637 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding "GO:0001779///natural killer cell differentiation+++GO:0002362///CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment+++GO:0002364///NK T cell lineage commitment+++GO:0002521///leukocyte differentiation+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007399///nervous system development+++GO:0010468///regulation of gene expression+++GO:0010976///positive regulation of neuron projection development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030098///lymphocyte differentiation+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0043373///CD4-positive, alpha-beta T cell lineage commitment+++GO:0043375///CD8-positive, alpha-beta T cell lineage commitment+++GO:0048535///lymph node development+++GO:0048541///Peyer's patch development+++GO:0097722///sperm motility+++GO:1901537///positive regulation of DNA demethylation+++GO:1902232///regulation of positive thymic T cell selection+++GO:2000179///positive regulation of neural precursor cell proliferation" 434778 434778 'Ccdc160' mRNA 130 134 125 3.78 4.14 4.11 1.62 1.57 1.97 4.01 1.72 63 55 69 129.6666667 62.33333333 2.74E-05 -1.068427657 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434784 434784 'Ldoc1' mRNA 16 12 18 0.72 0.53 0.86 0.86 1.12 0.93 0.703333333 0.97 22 28 23 15.33333333 24.33333333 0.304101872 0.650506506 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0001893///maternal placenta development+++GO:0060137///maternal process involved in parturition+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071225///cellular response to muramyl dipeptide+++GO:1903547///regulation of growth hormone activity 434794 434794 'Xlr4a' mRNA 6.86 9.35 6.71 0.34 0.46 0.4 0.7 0.81 1.14 0.4 0.883333333 15.53 16.26 25.59 7.64 19.12666667 0.061516683 1.409158363 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 434797 434797 'Gm5640' mRNA 0 0 1.56 0 0 0.03 0 0.04 0 0.01 0.013333333 0 2.11 0 0.52 0.703333333 0.863090843 0.906589207 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434843 434843 'Rps12-ps11' mRNA 0 0 0.34 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.113333333 0 434863 434863 'Gm15128' mRNA 0 3 0 0 0.1 0 0 0.04 0 0.033333333 0.013333333 0 1.17 0 1 0.39 0.753543289 -1.448551084 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 434866 434866 'Gm15127' mRNA 0 8 3.51 0 0.22 0.13 0.09 0 0.04 0.116666667 0.043333333 2.78 0 1.4 3.836666667 1.393333333 0.39370097 -1.886548025 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 435145 435145 'Shisa8' mRNA 201 224 90 6.22 6.78 2.97 1.34 0.89 1.45 5.323333333 1.226666667 49 33 51 171.6666667 44.33333333 1.44E-09 -1.949810228 GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0032591///dendritic spine membrane+++GO:0045211///postsynaptic membrane GO:0003674///molecular_function GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:2000311///regulation of AMPA receptor activity 435350 435350 'Serpinb6e' mRNA 2 0 1 0.08 0 0.04 0 0 0 0.04 0 0 0 0 1 0 0.60428608 -2.461629596 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0097180///serine protease inhibitor complex GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity GO:0007605///sensory perception of sound+++GO:0010951///negative regulation of endopeptidase activity+++GO:0071470///cellular response to osmotic stress 435391 435391 'Dupd1' mRNA 20 13 14 1.08 0.71 0.84 0.15 0.51 0.26 0.876666667 0.306666667 3 10 5 15.66666667 6 0.103788471 -1.387716811 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033549///MAP kinase phosphatase activity+++GO:0042803///protein homodimerization activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042593///glucose homeostasis+++GO:0042692///muscle cell differentiation+++GO:0043409///negative regulation of MAPK cascade+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 435528 435528 'Glyatl3' mRNA 1 2 1 0.02 0.03 0.02 0.02 0.02 0 0.023333333 0.013333333 1 1 0 1.333333333 0.666666667 0.752606026 -1.004745478 GO:0005575///cellular_component+++GO:0005739///mitochondrion "GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047961///glycine N-acyltransferase activity" GO:0008150///biological_process 435529 435529 'Adgrf2' mRNA 9 10 10 0.08 0.08 0.09 0.01 0.07 0.09 0.083333333 0.056666667 1 7 8 9.666666667 5.333333333 0.445491916 -0.861858945 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 435626 435626 'Rufy4' mRNA 439 395 439 9.64 8.35 10.05 5.95 5.46 5.88 9.346666667 5.763333333 307 271 293 424.3333333 290.3333333 8.54E-05 -0.562222786 GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0046872///metal ion binding GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0016239///positive regulation of macroautophagy+++GO:0071353///cellular response to interleukin-4 435653 435653 'Fcrlb' mRNA 789 875 791 27.41 28.85 28.27 5.28 3.53 5.18 28.17666667 4.663333333 186 130 183 818.3333333 166.3333333 7.29E-64 -2.311547418 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane GO:0004888///transmembrane signaling receptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0050777///negative regulation of immune response 435684 435684 'Shf' mRNA 88 78 58 1.01 0.75 0.59 1.07 0.8 0.89 0.783333333 0.92 66 67 64 74.66666667 65.66666667 0.614783931 -0.190932952 GO:0005575///cellular_component GO:0001784///phosphotyrosine residue binding GO:0006915///apoptotic process 435766 435766 'Tnni3k' mRNA 9 8 3 0.16 0.14 0.06 0.08 0.02 0.05 0.12 0.05 5 1 3 6.666666667 3 0.398214645 -1.155560857 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031013///troponin I binding+++GO:0046872///metal ion binding GO:0002027///regulation of heart rate+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0055117///regulation of cardiac muscle contraction+++GO:0086069///bundle of His cell to Purkinje myocyte communication+++GO:1903779///regulation of cardiac conduction 435791 435791 'Gm13271' mRNA 1.09 1.48 0 0.16 0.21 0 0 0.15 0 0.123333333 0.05 0 1.17 0 0.856666667 0.39 0.863090843 -0.875251456 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0097190///apoptotic signaling pathway 435811 435811 'Ldlrad2' mRNA 7.02 8.04 8.7 0.22 0.19 0.21 0.06 0.15 0.08 0.206666667 0.096666667 3 5.25 3 7.92 3.75 0.364889809 -1.074408365 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 435864 435864 'Vmn2r9' mRNA 0 0.5 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.166666667 0 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 435921 435921 'Clec2f' mRNA 0 0 1 0 0 0.04 0.03 0.03 0.1 0.013333333 0.053333333 1 1 1 0.333333333 1 0.707083372 1.469273284 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0046703///natural killer cell lectin-like receptor binding 435965 435965 'Lrp3' mRNA 247.41 230.06 247.52 3.37 3.08 3.57 1.78 2.22 1.93 3.34 1.976666667 151 183.36 157.47 241.6633333 163.9433333 0.002438215 -0.572229097 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation 436008 436008 'Gm5737' mRNA 632 636 600 12.76 12.63 12.84 0.68 0.73 0.75 12.74333333 0.72 39 40 41 622.6666667 40 4.02E-106 -3.971670608 GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006694///steroid biosynthetic process 436022 436022 'Dnaaf3' mRNA 344.75 320.68 234.03 8.69 7.97 6.26 1.7 1.74 1.99 7.64 1.81 77 77.42 87.69 299.82 80.70333333 2.14E-21 -1.902605379 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0030030///cell projection organization+++GO:0044458///motile cilium assembly+++GO:0070286///axonemal dynein complex assembly 436062 436062 'Cibar2' mRNA 3 0 1 0.2 0 0.07 0 0.12 0.12 0.09 0.08 0 2 2 1.333333333 1.333333333 0.999437028 0.00245902 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 436090 436090 'Gpr62' mRNA 164 156 146 4.61 4.32 4.35 1.88 1.55 1.44 4.426666667 1.623333333 77 62 57 155.3333333 65.33333333 1.53E-07 -1.261862343 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0042802///identical protein binding+++GO:1990763///arrestin family protein binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0048016///inositol phosphate-mediated signaling 436100 436100 'Gm21814' mRNA 22 27 46 0.42 0.5 0.92 0.46 0.3 0.31 0.613333333 0.356666667 28 18 18 31.66666667 21.33333333 0.312425588 -0.600617232 "GO:0006355///regulation of transcription, DNA-templated" 436240 436240 'Foxr2' mRNA 4 1 3 0.07 0.02 0.05 0 0 0 0.046666667 0 0 0 0 2.666666667 0 0.138048714 -3.878262044 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated" 436336 436336 'Gm5767' mRNA 5 1 2 0.35 0.07 0.21 0.22 0.26 0 0.21 0.16 3 4 0 2.666666667 2.333333333 0.926336321 -0.200770403 GO:0005575///cellular_component+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 436440 436440 'Gpr31b' mRNA 6 3 2 0.4 0.2 0.14 0.47 0.3 1.03 0.246666667 0.6 8 5 17 3.666666667 10 0.197853875 1.445000075 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045125///bioactive lipid receptor activity+++GO:0050544///arachidonic acid binding GO:0002237///response to molecule of bacterial origin+++GO:0002931///response to ischemia+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010447///response to acidic pH+++GO:0050728///negative regulation of inflammatory response+++GO:0050778///positive regulation of immune response 442801 442801 'Arhgef15' mRNA 63.07 60.21 92.1 0.76 0.75 1.26 1.8 1.56 1.4 0.923333333 1.586666667 160.97 134.91 125.32 71.79333333 140.4 6.41E-04 0.940055141 GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0050790///regulation of catalytic activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0090630///activation of GTPase activity+++GO:2000297///negative regulation of synapse maturation 442827 442827 'Rab44' mRNA 16 30 11 0.28 0.44 0.2 0.3 0.58 0.42 0.306666667 0.433333333 18 33 31 19 27.33333333 0.423638379 0.532315695 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding 442834 442834 'D830031N03Rik' mRNA 413 367 254 2.61 2.28 1.7 1.35 1.21 1.8 2.196666667 1.453333333 246 216 318 344.6666667 260 0.04340922 -0.410416254 GO:0003674///molecular_function GO:0008150///biological_process 445007 445007 'Nup85' mRNA 733 844 785 19.19 21.79 21.81 20.58 20.74 21.67 20.93 20.99666667 903 888 921 787.3333333 904 0.080699757 0.18746705 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031080///nuclear pore outer ring+++GO:0031965///nuclear membrane" GO:0017056///structural constituent of nuclear pore+++GO:0031727///CCR2 chemokine receptor binding "GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006935///chemotaxis+++GO:0015031///protein transport+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048246///macrophage chemotaxis+++GO:0051028///mRNA transport+++GO:0072006///nephron development" 446101 446101 'Xrra1' mRNA 48 40 43 1.01 0.85 0.96 0.22 0.38 0.34 0.94 0.313333333 12 20 18 43.66666667 16.66666667 0.003234771 -1.398774881 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0010165///response to X-ray 448850 448850 'Znhit3' mRNA 482.02 520.26 455.48 30.71 32.89 30.98 28.91 31.05 31.31 31.52666667 30.42333333 519.1 543.68 541.6 485.92 534.7933333 0.344405728 0.128129008 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0070761///pre-snoRNP complex GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000492///box C/D snoRNP assembly+++GO:0048254///snoRNA localization" 448987 448987 'Fbxl7' mRNA 85 55 64 0.99 0.63 0.8 0.71 0.71 0.86 0.806666667 0.76 70 68 82 68 73.33333333 0.822791725 0.097452693 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000209///protein polyubiquitination+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0051301///cell division 449000 449000 'Zfp960' mRNA 187.55 230.14 199.27 4.08 4.68 4.37 3.71 3.39 3.84 4.376666667 3.646666667 200.92 174.95 200.36 205.6533333 192.0766667 0.6273246 -0.113505271 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 449521 449521 'Zfp213' mRNA 421 443 421 8.72 9.04 9.25 5.19 5.22 5.77 9.003333333 5.393333333 288 283 310 428.3333333 293.6666667 4.39E-05 -0.556152226 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 450219 450219 'Gsdma3' mRNA 1.04 0 2 0.03 0 0.05 0.16 0.02 0.05 0.026666667 0.076666667 7.38 1.01 1.98 1.013333333 3.456666667 0.507020307 1.526646059 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0001786///phosphatidylserine binding+++GO:0005543///phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0022829///wide pore channel activity+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:1901612///cardiolipin binding" GO:0001942///hair follicle development+++GO:0001949///sebaceous gland cell differentiation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0012501///programmed cell death+++GO:0030879///mammary gland development+++GO:0031069///hair follicle morphogenesis+++GO:0035019///somatic stem cell population maintenance+++GO:0036331///avascular cornea development in camera-type eye+++GO:0042633///hair cycle+++GO:0042637///catagen+++GO:0042640///anagen+++GO:0042742///defense response to bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0043588///skin development+++GO:0051259///protein complex oligomerization+++GO:0051886///negative regulation of timing of anagen+++GO:0055085///transmembrane transport+++GO:0070269///pyroptosis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 474156 474156 'Zbtb9' mRNA 365 348 272 7.24 6.8 5.72 5.1 6.37 5.22 6.586666667 5.563333333 296 361 293 328.3333333 316.6666667 0.796280494 -0.057491879 GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 474160 474160 'Smim40' mRNA 27.92 26.6 13.1 1.89 1.84 1.12 1.32 2.21 2.29 1.616666667 1.94 20.05 31.05 33.55 22.54 28.21666667 0.590348846 0.351710321 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane 494448 494448 'Cbx6' mRNA 3182.97 3092.43 2262.37 31.1 29.71 23.45 26.55 24.68 24.11 28.08666667 25.11333333 3127.73 2840.69 2751.92 2845.923333 2906.78 0.861396595 0.024515763 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0031519///PcG protein complex GO:0003727///single-stranded RNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization 494468 494468 'Armcx5' mRNA 297.07 348.58 383.44 5.8 6.7 7.94 4.92 3.81 3.99 6.813333333 4.24 289.65 219.29 227.45 343.03 245.4633333 0.00508555 -0.502620062 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 494504 494504 'Apcdd1' mRNA 107 104 97 1.68 1.6 1.63 1.58 1.52 1.69 1.636666667 1.596666667 116 107 119 102.6666667 114 0.643343259 0.139987529 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017147///Wnt-protein binding+++GO:0042802///identical protein binding GO:0001942///hair follicle development+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0043615///astrocyte cell migration 497071 497071 'Rnase13' mRNA 2 0 3 0.07 0 0.11 0 0.03 0.03 0.06 0.02 0 1 1 1.666666667 0.666666667 0.662234497 -1.353249418 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003676///nucleic acid binding+++GO:0004540///ribonuclease activity GO:0090501///RNA phosphodiester bond hydrolysis 497097 497097 'Xkr4' mRNA 23 22.06 26 0.16 0.26 0.21 0.08 0.06 0.04 0.21 0.06 8 7 10 23.68666667 8.333333333 0.019769838 -1.521919266 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0017128///phospholipid scramblase activity+++GO:0042803///protein homodimerization activity GO:0043652///engulfment of apoptotic cell+++GO:0070782///phosphatidylserine exposure on apoptotic cell surface+++GO:1902742///apoptotic process involved in development 497106 497106 'Rnase12' mRNA 2 2 0 0.3 0.29 0 0.65 0.27 0.13 0.196666667 0.35 5 2 1 1.333333333 2.666666667 0.668579239 1.004051407 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0004540///ribonuclease activity+++GO:0046872///metal ion binding "GO:0001501///skeletal system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032922///circadian regulation of gene expression+++GO:0040015///negative regulation of multicellular organism growth+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0090501///RNA phosphodiester bond hydrolysis" 497113 497113 'Rnase11' mRNA 0 1 0 0 0.1 0 0.03 0 0 0.033333333 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003676///nucleic acid binding+++GO:0004540///ribonuclease activity GO:0008150///biological_process+++GO:0090501///RNA phosphodiester bond hydrolysis 497652 497652 'Acd' mRNA 809 815 777 31.78 30.93 31.82 27.71 26.36 27.81 31.51 27.29333333 818 755 782 800.3333333 785 0.755834628 -0.039889206 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0016604///nuclear body+++GO:0070187///shelterin complex" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0044877///protein-containing complex binding+++GO:0070182///DNA polymerase binding "GO:0000723///telomere maintenance+++GO:0001501///skeletal system development+++GO:0001655///urogenital system development+++GO:0006886///intracellular protein transport+++GO:0007004///telomere maintenance via telomerase+++GO:0016233///telomere capping+++GO:0030326///embryonic limb morphogenesis+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0032202///telomere assembly+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0035282///segmentation+++GO:0051973///positive regulation of telomerase activity+++GO:0060381///positive regulation of single-stranded telomeric DNA binding+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0070200///establishment of protein localization to telomere" 503610 503610 'Zdhhc18' mRNA 194 158 143 4.06 3.24 3.15 7.11 5.63 6.72 3.483333333 6.486666667 392 300 359 165 350.3333333 4.09E-10 1.075314418 04391///Hippo signaling pathway - fly GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0034613///cellular protein localization 503844 503844 'Ang5' mRNA 5 13 14 0.5 1.3 1.49 7.37 6.46 7.25 1.096666667 7.026666667 83.84 71.5 79.59 10.66666667 78.31 9.16E-11 2.846966215 05014///Amyotrophic lateral sclerosis GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0001525///angiogenesis+++GO:0019731///antibacterial humoral response+++GO:0045087///innate immune response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 503847 503847 'Ear14' mRNA 0 0 1 0 0 0.21 0 0 0 0.07 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0002227///innate immune response in mucosa+++GO:0006935///chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 504186 504186 'Chrna10' mRNA 4800 5052 5009 101.1 105.44 112.56 8.54 9.68 8.31 106.3666667 8.843333333 467 506 431 4953.666667 468 0 -3.416566645 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098981///cholinergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential "GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042472///inner ear morphogenesis+++GO:0050877///nervous system process+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0070373///negative regulation of ERK1 and ERK2 cascade" 504193 504193 'Npcd' mRNA 206.78 299.91 148.97 2.42 3.45 1.84 1.84 1.4 1.56 2.57 1.6 180.97 134.58 149.05 218.5533333 154.8666667 0.045525401 -0.498411353 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0098978///glutamatergic synapse GO:0008029///pentraxin receptor activity+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 50490 50490 'Nox4' mRNA 32 25 24 0.46 0.35 0.37 0.75 0.69 0.89 0.393333333 0.776666667 60 54 69 27 61 0.002577777 1.165800207 04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0043020///NADPH oxidase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0097038///perinuclear endoplasmic reticulum "GO:0016174///NAD(P)H oxidase activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050664///oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor+++GO:0072341///modified amino acid binding+++GO:1990782///protein tyrosine kinase binding" GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0003015///heart process+++GO:0006801///superoxide metabolic process+++GO:0006952///defense response+++GO:0007568///aging+++GO:0007569///cell aging+++GO:0008285///negative regulation of cell proliferation+++GO:0010467///gene expression+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0042554///superoxide anion generation+++GO:0043065///positive regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045453///bone resorption+++GO:0050667///homocysteine metabolic process+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055007///cardiac muscle cell differentiation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0071333///cellular response to glucose stimulus+++GO:0071480///cellular response to gamma radiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0072593///reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000573///positive regulation of DNA biosynthetic process 50492 50492 'Thop1' mRNA 1013 1001 881 21.77 21.18 20.09 13.02 12.13 12.47 21.01333333 12.54 697 634 646 965 659 2.91E-09 -0.560540717 04614///Renin-angiotensin system+++05143///African trypanosomiasis GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0035556///intracellular signal transduction 50493 50493 'Txnrd1' mRNA 3583 3770 1673 57.08 59.37 28.72 19.12 24.85 24.04 48.39 22.67 1354 1734 1662 3008.666667 1583.333333 0.015069889 -0.917744259 00450///Selenocompound metabolism+++05200///Pathways in cancer+++05225///Hepatocellular carcinoma GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0043025///neuronal cell body "GO:0004791///thioredoxin-disulfide reductase activity+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0033797///selenate reductase activity+++GO:0042802///identical protein binding+++GO:0045340///mercury ion binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0001707///mesoderm formation+++GO:0006979///response to oxidative stress+++GO:0007369///gastrulation+++GO:0008283///cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0016259///selenocysteine metabolic process+++GO:0042537///benzene-containing compound metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0045454///cell redox homeostasis+++GO:0070995///NADPH oxidation+++GO:0098869///cellular oxidant detoxification 50496 50496 'E2f6' mRNA 202 226 179 4.49 4.99 4.22 3.57 2.68 4.05 4.566666667 3.433333333 183 133 201 202.3333333 172.3333333 0.299588437 -0.241537024 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005667///transcription factor complex+++GO:0071339///MLL1 complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity" "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle" 50497 50497 'Hspa14' mRNA 746 832 753 24.08 26.49 25.8 28.03 28.89 28 25.45666667 28.30666667 999 1005 965 777 989.6666667 4.25E-04 0.338045073 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0031072///heat shock protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0016192///vesicle-mediated transport+++GO:0034620///cellular response to unfolded protein+++GO:0042026///protein refolding+++GO:0051085///chaperone cofactor-dependent protein refolding 50498 50498 'Ebi3' mRNA 41 50 76 2.16 2.6 4.25 9.03 9.92 8.21 3.003333333 9.053333333 195 210 171 55.66666667 192 3.73E-11 1.765024839 04060///Cytokine-cytokine receptor interaction+++04659///Th17 cell differentiation GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0017046///peptide hormone binding+++GO:0019955///cytokine binding+++GO:0045523///interleukin-27 receptor binding GO:0019221///cytokine-mediated signaling pathway+++GO:0033210///leptin-mediated signaling pathway+++GO:0042098///T cell proliferation 50500 50500 'Ttpa' mRNA 24 12 14 0.46 0.24 0.3 0.49 0.45 0.39 0.333333333 0.443333333 31 28 24 16.66666667 27.66666667 0.232046441 0.720555815 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005829///cytosol "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0008431///vitamin E binding+++GO:0019842///vitamin binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0120013///intermembrane lipid transfer activity+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0001890///placenta development+++GO:0001892///embryonic placenta development+++GO:0007584///response to nutrient+++GO:0009268///response to pH+++GO:0009636///response to toxic substance+++GO:0032502///developmental process+++GO:0042360///vitamin E metabolic process+++GO:0051180///vitamin transport+++GO:0051452///intracellular pH reduction+++GO:0060548///negative regulation of cell death+++GO:0090212///negative regulation of establishment of blood-brain barrier+++GO:0120009///intermembrane lipid transfer+++GO:1900223///positive regulation of amyloid-beta clearance 50501 50501 'Prok2' mRNA 10 13 8 0.41 0.53 0.35 1.32 1.46 1.41 0.43 1.396666667 37 40 38 10.33333333 38.33333333 3.61E-04 1.88578334 GO:0005576///extracellular region GO:0001664///G protein-coupled receptor binding+++GO:0008083///growth factor activity GO:0000187///activation of MAPK activity+++GO:0001525///angiogenesis+++GO:0001935///endothelial cell proliferation+++GO:0003349///epicardium-derived cardiac endothelial cell differentiation+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007283///spermatogenesis+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045765///regulation of angiogenesis+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0048511///rhythmic process+++GO:0051781///positive regulation of cell division+++GO:0060976///coronary vasculature development+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0060983///epicardium-derived cardiac vascular smooth muscle cell differentiation 50505 50505 'Ercc4' mRNA 666.89 640 660 5.26 4.96 5.52 3.94 3.83 4 5.246666667 3.923333333 575 546 566 655.63 562.3333333 0.043380071 -0.233855808 03420///Nucleotide excision repair+++03460///Fanconi anemia pathway "GO:0000109///nucleotide-excision repair complex+++GO:0000110///nucleotide-excision repair factor 1 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0070522///ERCC4-ERCC1 complex" GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0008022///protein C-terminus binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0047485///protein N-terminus binding+++GO:1990599///3' overhang single-stranded DNA endodeoxyribonuclease activity+++GO:1990841///promoter-specific chromatin binding "GO:0000712///resolution of meiotic recombination intermediates+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0009650///UV protection+++GO:0010506///regulation of autophagy+++GO:0032205///negative regulation of telomere maintenance+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0034644///cellular response to UV+++GO:0061819///telomeric DNA-containing double minutes formation+++GO:1901255///nucleotide-excision repair involved in interstrand cross-link repair+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1905765///negative regulation of protection from non-homologous end joining at telomere+++GO:1905768///negative regulation of double-stranded telomeric DNA binding" 50518 50518 'a' mRNA 106 108 139 0.83 0.97 1.58 0.57 0.63 0.63 1.126666667 0.61 60 70 71 117.6666667 67 0.003178379 -0.829565887 04916///Melanogenesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0005184///neuropeptide hormone activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031779///melanocortin receptor binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding "GO:0006091///generation of precursor metabolites and energy+++GO:0008343///adult feeding behavior+++GO:0009755///hormone-mediated signaling pathway+++GO:0016032///viral process+++GO:0032402///melanosome transport+++GO:0032438///melanosome organization+++GO:0040030///regulation of molecular function, epigenetic+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0071514///genetic imprinting" 50523 50523 'Lats2' mRNA 911.97 935.94 478 9.74 9.53 5.28 6.58 6.75 7.82 8.183333333 7.05 736.6 712.94 815 775.3033333 754.8466667 0.926067403 -0.035531911 04214///Apoptosis - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001827///inner cell mass cell fate commitment+++GO:0001828///inner cell mass cellular morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0009755///hormone-mediated signaling pathway+++GO:0016310///phosphorylation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030216///keratinocyte differentiation+++GO:0034613///cellular protein localization+++GO:0035329///hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0046620///regulation of organ growth+++GO:0051301///cell division+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900181///negative regulation of protein localization to nucleus 50524 50524 'Sall2' mRNA 3970 4107 3155 43.92 44.68 37.04 15.51 13.83 14.98 41.88 14.77333333 1603 1400 1498 3744 1500.333333 1.31E-63 -1.326921885 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001654///eye development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021915///neural tube development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 50525 50525 'Spag6l' mRNA 1068 1078 1122 24.21 24.02 26.92 2.14 1.81 1.85 25.05 1.933333333 108 90 90 1089.333333 96 1.33E-149 -3.518915765 GO:0001669///acrosomal vesicle+++GO:0002177///manchette+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece+++GO:1990716///axonemal central apparatus GO:0005515///protein binding+++GO:0008017///microtubule binding "GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0006931///substrate-dependent cell migration, cell attachment to substrate+++GO:0007283///spermatogenesis+++GO:0007288///sperm axoneme assembly+++GO:0010761///fibroblast migration+++GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0034613///cellular protein localization+++GO:0043149///stress fiber assembly+++GO:0043583///ear development+++GO:0044458///motile cilium assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0046847///filopodium assembly+++GO:0051301///cell division+++GO:0090175///regulation of establishment of planar polarity+++GO:0090660///cerebrospinal fluid circulation+++GO:1905515///non-motile cilium assembly+++GO:1990138///neuron projection extension" 50527 50527 'Ero1a' mRNA 899 978 774 10.93 11.69 9.98 13.75 13.72 13.63 10.86666667 13.7 1302 1269 1250 883.6666667 1273.666667 5.84E-09 0.519141035 04141///Protein processing in endoplasmic reticulum+++05110///Vibrio cholerae infection+++05417///Lipid and atherosclerosis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030425///dendrite "GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0016972///thiol oxidase activity+++GO:0071949///FAD binding" GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0010260///animal organ senescence+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0022417///protein maturation by protein folding+++GO:0030198///extracellular matrix organization+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045454///cell redox homeostasis+++GO:0050873///brown fat cell differentiation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071456///cellular response to hypoxia 50528 50528 'Tmprss2' mRNA 301 269 275 5.35 4.77 5.23 7.4 6.37 5.98 5.116666667 6.583333333 482 408 371 281.6666667 420.3333333 1.64E-04 0.563908142 05164///Influenza A+++05171///Coronavirus disease - COVID-19+++05202///Transcriptional misregulation in cancer+++05215///Prostate cancer GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0016540///protein autoprocessing+++GO:0046598///positive regulation of viral entry into host cell 50529 50529 'Mrps7' mRNA 1063 1101 1013 35.2 35.94 35.59 35.01 33.83 35.11 35.57666667 34.65 1215 1146 1179 1059 1180 0.108228854 0.144822402 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0032543///mitochondrial translation 50530 50530 'Mfap5' mRNA 80 83 65 3.14 3.21 2.71 3.79 4.03 3.71 3.02 3.843333333 111 115 105 76 110.3333333 0.04986311 0.530089178 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005515///protein binding+++GO:0030023///extracellular matrix constituent conferring elasticity GO:0048048///embryonic eye morphogenesis+++GO:0060216///definitive hemopoiesis+++GO:0097435///supramolecular fiber organization 50701 50701 'Elane' mRNA 4 13 7 0.28 0.91 0.53 0.31 0.19 0.06 0.573333333 0.186666667 5 3 1 8 3 0.257776019 -1.425851096 04613///Neutrophil extracellular trap formation+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0017053///transcriptional repressor complex+++GO:0030141///secretory granule+++GO:0062023///collagen-containing extracellular matrix GO:0002020///protease binding+++GO:0003714///transcription corepressor activity+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019955///cytokine binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001878///response to yeast+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002812///biosynthetic process of antibacterial peptides active against Gram-negative bacteria+++GO:0006508///proteolysis+++GO:0006909///phagocytosis+++GO:0009411///response to UV+++GO:0032496///response to lipopolysaccharide+++GO:0032682///negative regulation of chemokine production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0042742///defense response to bacterium+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050778///positive regulation of immune response+++GO:0050832///defense response to fungus+++GO:0050900///leukocyte migration+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0070947///neutrophil mediated killing of fungus+++GO:1903238///positive regulation of leukocyte tethering or rolling 50706 50706 'Postn' mRNA 117 87 99 1.97 1.45 1.76 6.33 6.09 5.67 1.726666667 6.03 424 400 366 101 396.6666667 1.39E-29 1.960816014 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0031012///extracellular matrix+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding GO:0001666///response to hypoxia+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0007155///cell adhesion+++GO:0008593///regulation of Notch signaling pathway+++GO:0009612///response to mechanical stimulus+++GO:0009888///tissue development+++GO:0014850///response to muscle activity+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030198///extracellular matrix organization+++GO:0032355///response to estradiol+++GO:0042060///wound healing+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0071307///cellular response to vitamin K+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1990138///neuron projection extension+++GO:1990523///bone regeneration+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 50708 50708 'H1f2' mRNA 303.31 342.55 314.99 29.5 33.06 32.51 51.26 48.1 54.17 31.69 51.17666667 602.76 550.36 614.59 320.2833333 589.2366667 1.56E-12 0.869010782 GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035327///transcriptionally active chromatin GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:0080182///histone H3-K4 trimethylation+++GO:0098532///histone H3-K27 trimethylation 50709 50709 'H1f4' mRNA 96.67 71.35 74.96 8.49 6.21 6.98 16.74 18 16.95 7.226666667 17.23 218.2 228.46 213.29 80.99333333 219.9833333 1.01E-11 1.44094493 GO:0000786///nucleosome+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016208///AMP binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0032564///dATP binding+++GO:0043531///ADP binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:0080182///histone H3-K4 trimethylation+++GO:0098532///histone H3-K27 trimethylation 50720 50720 'Sacs' mRNA 95 108 81 0.47 0.44 0.31 0.42 0.54 0.59 0.406666667 0.516666667 142 130 163 94.66666667 145 0.011908558 0.607274178 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0030544///Hsp70 protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0051087///chaperone binding+++GO:0070628///proteasome binding GO:0090084///negative regulation of inclusion body assembly 50721 50721 'Sirt6' mRNA 668 607 635 23.58 21.1 23.63 17.17 18.23 16.82 22.77 17.40666667 560 578 532 636.6666667 556.6666667 0.094214995 -0.206125572 00760///Nicotinate and nicotinamide metabolism+++04714///Thermogenesis+++05230///Central carbon metabolism in cancer "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0099115///chromosome, subtelomeric region" GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0004407///histone deacetylase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017136///NAD-dependent histone deacetylase activity+++GO:0019213///deacetylase activity+++GO:0033558///protein deacetylase activity+++GO:0046872///metal ion binding+++GO:0046969///NAD-dependent histone deacetylase activity (H3-K9 specific)+++GO:0070403///NAD+ binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003247///post-embryonic cardiac muscle cell growth involved in heart morphogenesis+++GO:0006284///base-excision repair+++GO:0006471///protein ADP-ribosylation+++GO:0006476///protein deacetylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0031648///protein destabilization+++GO:0031667///response to nutrient levels+++GO:0031940///positive regulation of chromatin silencing at telomere+++GO:0032206///positive regulation of telomere maintenance+++GO:0042593///glucose homeostasis+++GO:0045820///negative regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046325///negative regulation of glucose import+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0061647///histone H3-K9 modification+++GO:0070932///histone H3 deacetylation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901485///positive regulation of transcription factor catabolic process+++GO:1902732///positive regulation of chondrocyte proliferation+++GO:1905549///positive regulation of telomeric heterochromatin assembly+++GO:1905555///positive regulation blood vessel branching+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:1990619///histone H3-K9 deacetylation+++GO:2000648///positive regulation of stem cell proliferation" 50722 50722 'Dkkl1' mRNA 12 1 15 0.75 0.07 1.16 2.35 2.45 2.22 0.66 2.34 37 39 34 9.333333333 36.66666667 0.002960158 1.943584456 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0039706///co-receptor binding+++GO:0048019///receptor antagonist activity GO:0007341///penetration of zona pellucida+++GO:0043065///positive regulation of apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000225///negative regulation of testosterone biosynthetic process+++GO:2000272///negative regulation of signaling receptor activity 50723 50723 'Icosl' mRNA 318 303 236 6.38 5.95 5.03 8.56 8.58 7.79 5.786666667 8.31 493 483 434 285.6666667 470 4.77E-07 0.710895937 04514///Cell adhesion molecules+++04672///Intestinal immune network for IgA production GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001817///regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042110///T cell activation+++GO:0042113///B cell activation+++GO:0045190///isotype switching+++GO:0050852///T cell receptor signaling pathway 50724 50724 'Sap30l' mRNA 50 47 57 1.9 1.76 2.3 2.05 2.64 1.74 1.986666667 2.143333333 62 78 51 51.33333333 63.66666667 0.468813497 0.296383827 05169///Epstein-Barr virus infection GO:0000118///histone deacetylase complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0031491///nucleosome binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0042393///histone binding+++GO:0044378///non-sequence-specific DNA binding, bending+++GO:0046872///metal ion binding+++GO:0070273///phosphatidylinositol-4-phosphate binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated" 50753 50753 'Fbxo8' mRNA 587.2 741.38 598.73 9.06 11.26 9.84 8.55 8.3 9.58 10.05333333 8.81 635.43 602.57 688.31 642.4366667 642.1033333 0.950494196 -0.010278186 GO:0000151///ubiquitin ligase complex GO:0005085///guanyl-nucleotide exchange factor activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity 50754 50754 'Fbxw7' mRNA 1937 2040 1953 27.96 29.08 30.03 6.09 5.3 5.29 29.02333333 5.56 512 430 422 1976.666667 454.6666667 2.18E-122 -2.133603662 04120///Ubiquitin mediated proteolysis GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:1990452///Parkin-FBXW7-Cul1 ubiquitin ligase complex "GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0030332///cyclin binding+++GO:0030674///protein binding, bridging+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0050816///phosphothreonine residue binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0001570///vasculogenesis+++GO:0001944///vasculature development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007062///sister chromatid cohesion+++GO:0007219///Notch signaling pathway+++GO:0008150///biological_process+++GO:0010629///negative regulation of gene expression+++GO:0010868///negative regulation of triglyceride biosynthetic process+++GO:0010883///regulation of lipid storage+++GO:0010992///ubiquitin recycling+++GO:0016567///protein ubiquitination+++GO:0030324///lung development+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032880///regulation of protein localization+++GO:0034644///cellular response to UV+++GO:0042752///regulation of circadian rhythm+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0055088///lipid homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070534///protein K63-linked ubiquitination+++GO:0090049///regulation of cell migration involved in sprouting angiogenesis+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903378///positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:2000639///negative regulation of SREBP signaling pathway+++GO:2001205///negative regulation of osteoclast development 50755 50755 'Fbh1' mRNA 1497.39 1590.73 1489.33 22.41 23.43 23.64 22.95 23.05 23.26 23.16 23.08666667 1770.72 1731.96 1730.71 1525.816667 1744.463333 0.020141961 0.181424868 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0019005///SCF ubiquitin ligase complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015616///DNA translocase activity+++GO:0016787///hydrolase activity+++GO:0043138///3'-5' DNA helicase activity "GO:0000724///double-strand break repair via homologous recombination+++GO:0000725///recombinational repair+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death+++GO:0016567///protein ubiquitination+++GO:0031297///replication fork processing+++GO:0032508///DNA duplex unwinding+++GO:0035562///negative regulation of chromatin binding+++GO:0048478///replication fork protection+++GO:0072429///response to intra-S DNA damage checkpoint signaling+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000042///negative regulation of double-strand break repair via homologous recombination" 50758 50758 'Fbxl17' mRNA 1157.42 1137.01 1013.87 3.98 3.82 3.71 2.26 2 2.16 3.836666667 2.14 741.31 642.05 686.06 1102.766667 689.8066667 7.84E-14 -0.687416429 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000209///protein polyubiquitination+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007399///nervous system development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0014033///neural crest cell differentiation+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051726///regulation of cell cycle 50759 50759 'Fbxo16' mRNA 504 512 468 7.21 7.21 7.1 2.11 2.14 1.81 7.173333333 2.02 170 168 141 494.6666667 159.6666667 3.81E-30 -1.642333363 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 50760 50760 'Fbxo17' mRNA 228 199 222 7.17 6.25 7.67 5.35 5.25 4.93 7.03 5.176666667 187 177 168 216.3333333 177.3333333 0.130583939 -0.300861794 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006516///glycoprotein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 50762 50762 'Fbxo6' mRNA 870 845 769 41.72 40.25 39.67 55.89 59.72 60.73 40.54666667 58.78 1319 1365 1384 828 1356 1.83E-16 0.701952891 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0044322///endoplasmic reticulum quality control compartment GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0061630///ubiquitin protein ligase activity GO:0006281///DNA repair+++GO:0006516///glycoprotein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006986///response to unfolded protein+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0097466///ubiquitin-dependent glycoprotein ERAD pathway 50764 50764 'Fbxo15' mRNA 23 11 23 0.81 0.37 0.86 0.03 0.13 0.1 0.68 0.086666667 1 4 3 19 2.666666667 0.001686715 -2.849372642 GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 50765 50765 'Tfr2' mRNA 15 13 9 0.24 0.22 0.18 0.33 0.08 0.34 0.213333333 0.25 21 5 20 12.33333333 15.33333333 0.752944406 0.302234752 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:1990712///HFE-transferrin receptor complex GO:0004998///transferrin receptor activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0039706///co-receptor binding GO:0006508///proteolysis+++GO:0006879///cellular iron ion homeostasis+++GO:0006898///receptor-mediated endocytosis+++GO:0006953///acute-phase response+++GO:0010039///response to iron ion+++GO:0033572///transferrin transport+++GO:0045807///positive regulation of endocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055072///iron ion homeostasis+++GO:0071281///cellular response to iron ion+++GO:0090277///positive regulation of peptide hormone secretion+++GO:1903319///positive regulation of protein maturation 50766 50766 'Crim1' mRNA 938 1006 894 9.35 9.75 9.22 6.97 5.84 6.59 9.44 6.466666667 808 657 742 946 735.6666667 2.33E-04 -0.374736093 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004857///enzyme inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005520///insulin-like growth factor binding+++GO:0030165///PDZ domain binding GO:0010951///negative regulation of endopeptidase activity+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0043086///negative regulation of catalytic activity+++GO:0045668///negative regulation of osteoblast differentiation 50767 50767 'Pnpla6' mRNA 1407 1419 1356 17.12 16.98 17.36 14.1 13.03 12.95 17.15333333 13.36 1336 1210 1191 1394 1245.666667 0.04339281 -0.174714656 00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102545///phosphatidyl phospholipase B activity GO:0001525///angiogenesis+++GO:0006629///lipid metabolic process+++GO:0009887///animal organ morphogenesis+++GO:0016042///lipid catabolic process+++GO:0046470///phosphatidylcholine metabolic process 50768 50768 'Dlc1' mRNA 640 631 499 8.37 8.61 7.68 7.87 5.99 6.06 8.22 6.64 638 510 515 590 554.3333333 0.523835111 -0.099290803 GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005901///caveola+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0032587///ruffle membrane+++GO:0045121///membrane raft GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0017166///vinculin binding+++GO:0042169///SH2 domain binding+++GO:0043274///phospholipase binding GO:0001843///neural tube closure+++GO:0003007///heart morphogenesis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007202///activation of phospholipase C activity+++GO:0008285///negative regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0021575///hindbrain morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030336///negative regulation of cell migration+++GO:0030900///forebrain development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043547///positive regulation of GTPase activity+++GO:0048041///focal adhesion assembly+++GO:0050790///regulation of catalytic activity+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:1900119///positive regulation of execution phase of apoptosis 50769 50769 'Atp8a2' mRNA 1400 1333 1114 19.02 17.81 16.05 1.29 1.34 1.1 17.62666667 1.243333333 109 111 90 1282.333333 103.3333333 9.99E-172 -3.641569549 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0015247///aminophospholipid transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity GO:0003011///involuntary skeletal muscle contraction+++GO:0006869///lipid transport+++GO:0007409///axonogenesis+++GO:0007568///aging+++GO:0010842///retina layer formation+++GO:0010976///positive regulation of neuron projection development+++GO:0010996///response to auditory stimulus+++GO:0015914///phospholipid transport+++GO:0031175///neuron projection development+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042472///inner ear morphogenesis+++GO:0042755///eating behavior+++GO:0043588///skin development+++GO:0045332///phospholipid translocation+++GO:0048666///neuron development+++GO:0050884///neuromuscular process controlling posture+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0060052///neurofilament cytoskeleton organization+++GO:0061092///positive regulation of phospholipid translocation 50770 50770 'Atp11a' mRNA 5344.3 5177.98 4970.46 33.16 32.04 33.18 10.25 8.82 10.85 32.79333333 9.973333333 1916.61 1566.99 1917.53 5164.246667 1800.376667 3.71E-96 -1.533450034 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:1990531///phospholipid-translocating ATPase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0090555///phosphatidylethanolamine-translocating ATPase activity GO:0001701///in utero embryonic development+++GO:0006869///lipid transport+++GO:0010831///positive regulation of myotube differentiation+++GO:0015914///phospholipid transport+++GO:0045332///phospholipid translocation 50771 50771 'Atp9b' mRNA 1103 1232 1229 12.92 13.93 15.06 11.77 12.15 10.85 13.97 11.59 1172 1198 1078 1188 1149.333333 0.622972494 -0.061043276 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006897///endocytosis+++GO:0015914///phospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation" 50772 50772 'Mapk6' mRNA 1432 1494 1382 18.33 18.81 18.77 18.84 17.97 20.16 18.63666667 18.99 1694 1579 1756 1436 1676.333333 0.008716334 0.211862914 04657///IL-17 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032156///septin cytoskeleton+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0060999///positive regulation of dendritic spine development 50773 50773 'Nt5c' mRNA 508 447 446 42.35 36.85 39.53 70.1 75.28 72.22 39.57666667 72.53333333 964 1011 957 467 977.3333333 2.27E-24 1.054652136 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0008252///nucleotidase activity+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019103///pyrimidine nucleotide binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050483///IMP 5'-nucleotidase activity GO:0000255///allantoin metabolic process+++GO:0006204///IMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0009223///pyrimidine deoxyribonucleotide catabolic process+++GO:0009264///deoxyribonucleotide catabolic process+++GO:0016311///dephosphorylation+++GO:0046050///UMP catabolic process+++GO:0046055///dGMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process 50776 50776 'Polg2' mRNA 155 146 146 5.77 5.36 5.76 5.02 5.24 5.42 5.63 5.226666667 155 158 162 149 158.3333333 0.779136555 0.076125765 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005760///gamma DNA polymerase complex+++GO:0042645///mitochondrial nucleoid GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0030337///DNA polymerase processivity factor activity+++GO:0042802///identical protein binding+++GO:0070182///DNA polymerase binding GO:0001701///in utero embryonic development+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006264///mitochondrial DNA replication+++GO:0006281///DNA repair+++GO:0022904///respiratory electron transport chain+++GO:0032042///mitochondrial DNA metabolic process+++GO:0070584///mitochondrion morphogenesis+++GO:0071897///DNA biosynthetic process+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 50778 50778 'Rgs1' mRNA 4 2 7 0.18 0.09 0.34 18.97 19.94 19.6 0.203333333 19.50333333 481 493 481 4.333333333 485 4.67E-56 6.794445925 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009617///response to bacterium+++GO:0009968///negative regulation of signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061737///leukotriene signaling pathway 50779 50779 'Rgs6' mRNA 123 116 109 1.43 1.08 1.04 0.6 0.45 0.37 1.183333333 0.473333333 77 50 44 116 57 3.49E-04 -1.039638474 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0032991///protein-containing complex GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0050790///regulation of catalytic activity 50780 50780 'Rgs3' mRNA 1541 1514 1390 21.51 20.53 19.91 11.85 11.69 12.17 20.65 11.90333333 934 912 863 1481.666667 903 2.83E-19 -0.725089419 04360///Axon guidance GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0050790///regulation of catalytic activity 50781 50781 'Dkk3' mRNA 12357 13374 12342 200.4 213.81 212.36 92.1 91.23 91.14 208.8566667 91.49 6510 6308 6239 12691 6352.333333 1.27E-84 -1.010079893 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0039706///co-receptor binding+++GO:0048019///receptor antagonist activity "GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032348///negative regulation of aldosterone biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000065///negative regulation of cortisol biosynthetic process+++GO:2000272///negative regulation of signaling receptor activity" 50782 50782 'Rgs11' mRNA 2393 2487 2421 53.26 54.21 56.98 10.62 13.61 12.01 54.81666667 12.08 552 687 604 2433.666667 614.3333333 2.93E-101 -1.996674378 GO:0032991///protein-containing complex+++GO:0044292///dendrite terminus GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031681///G-protein beta-subunit binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 50783 50783 'Lsm4' mRNA 1021 997 864 80.49 77.83 72.69 70.08 93.27 93.91 77.00333333 85.75333333 1012 1304 1324 960.6666667 1213.333333 0.005909742 0.330508818 03018///RNA degradation+++03040///Spliceosome GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0097526///spliceosomal tri-snRNP complex+++GO:0120115///Lsm2-8 complex GO:0003723///RNA binding+++GO:0017070///U6 snRNA binding+++GO:0042731///PH domain binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0033962///cytoplasmic mRNA processing body assembly" 50784 50784 'Plpp2' mRNA 1624 1869 1586 57.89 65.84 60.29 77.55 70.43 73.47 61.34 73.81666667 2487 2220 2289 1693 2332 2.43E-09 0.451140947 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00600///Sphingolipid metabolism+++04072///Phospholipase D signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04975///Fat digestion and absorption+++05231///Choline metabolism in cancer GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0042577///lipid phosphatase activity GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0006672///ceramide metabolic process+++GO:0007165///signal transduction+++GO:0016311///dephosphorylation+++GO:0046839///phospholipid dephosphorylation+++GO:1902806///regulation of cell cycle G1/S phase transition 50785 50785 'Hs6st1' mRNA 509 502 329 7.42 7.2 5.09 4.85 4.13 4.95 6.57 4.643333333 383 319 379 446.6666667 360.3333333 0.064486697 -0.314406938 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0017095///heparan sulfate 6-O-sulfotransferase activity "GO:0001525///angiogenesis+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification+++GO:0048286///lung alveolus development+++GO:0048666///neuron development+++GO:0060716///labyrinthine layer blood vessel development" 50786 50786 'Hs6st2' mRNA 945 1001 918 12.89 13.55 13.4 3.77 2.86 3.81 13.28 3.48 320 239 318 954.6666667 292.3333333 3.53E-47 -1.720095194 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0017095///heparan sulfate 6-O-sulfotransferase activity "GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification" 50787 50787 'Hs6st3' mRNA 5 3 0 0.08 0.04 0 0 0.04 0.04 0.04 0.026666667 0 1 1 2.666666667 0.666666667 0.442182042 -1.970145439 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0017095///heparan sulfate 6-O-sulfotransferase activity "GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification" 50788 50788 'Fbxl8' mRNA 59 54 43 1.78 1.6 1.37 4.09 3.01 2.98 1.583333333 3.36 156 112 110 52 126 6.24E-06 1.265951102 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0000086///G2/M transition of mitotic cell cycle+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0051726///regulation of cell cycle 50789 50789 'Fbxl3' mRNA 813.39 913.82 749.07 12.89 14.03 12.87 10.19 9.86 10.25 13.26333333 10.1 738.28 705.81 711.33 825.4266667 718.4733333 0.047682027 -0.209742975 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0019005///SCF ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031648///protein destabilization+++GO:0042752///regulation of circadian rhythm+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle 50790 50790 'Acsl4' mRNA 2278 2226 2138 23.83 22.84 23.65 24.69 21.18 24.13 23.44 23.33333333 2676 2243 2524 2214 2481 0.058116237 0.151448341 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome+++04216///Ferroptosis+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044233///Mitochondria-associated ER Membrane GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047676///arachidonate-CoA ligase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007584///response to nutrient+++GO:0008610///lipid biosynthetic process+++GO:0015908///fatty acid transport+++GO:0019217///regulation of fatty acid metabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0030182///neuron differentiation+++GO:0030307///positive regulation of cell growth+++GO:0032024///positive regulation of insulin secretion+++GO:0032307///negative regulation of prostaglandin secretion+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0060136///embryonic process involved in female pregnancy+++GO:0060996///dendritic spine development+++GO:0070672///response to interleukin-15 50791 50791 'Magi2' mRNA 414 376 358 3.18 2.83 2.92 1.02 1.1 1.15 2.976666667 1.09 152 161 166 382.6666667 159.6666667 1.89E-16 -1.271100362 04015///Rap1 signaling pathway+++04151///PI3K-Akt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0019902///phosphatase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0044877///protein-containing complex binding+++GO:0046332///SMAD binding+++GO:0060090///molecular adaptor activity+++GO:0070697///activin receptor binding+++GO:0070699///type II activin receptor binding+++GO:0098879///structural constituent of postsynaptic specialization+++GO:0098919///structural constituent of postsynaptic density GO:0002092///positive regulation of receptor internalization+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0030336///negative regulation of cell migration+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0038180///nerve growth factor signaling pathway+++GO:0043113///receptor clustering+++GO:0051726///regulation of cell cycle+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060395///SMAD protein signal transduction+++GO:0071850///mitotic cell cycle arrest+++GO:0072015///glomerular visceral epithelial cell development+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0099179///regulation of synaptic membrane adhesion+++GO:0099562///maintenance of postsynaptic density structure+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000809///positive regulation of synaptic vesicle clustering 50793 50793 'Orc3' mRNA 1288.22 1217 1268.25 20.85 19.71 22.15 18.08 17.15 18.01 20.90333333 17.74666667 1223.31 1143 1150 1257.823333 1172.103333 0.241099392 -0.115244062 04110///Cell cycle GO:0000785///chromatin+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005656///nuclear pre-replicative complex+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0031261///DNA replication preinitiation complex GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding GO:0006260///DNA replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication+++GO:0006270///DNA replication initiation+++GO:0006275///regulation of DNA replication+++GO:0061351///neural precursor cell proliferation 50794 50794 'Klf13' mRNA 3916 3624 3979 32.42 29.49 34.94 34.45 38.34 34.9 32.28333333 35.89666667 4792 5211 4703 3839.666667 4902 2.02E-05 0.33886396 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 50795 50795 'Sh3bgr' mRNA 12 17 10 0.55 0.77 0.48 0.6 0.49 0.49 0.6 0.526666667 15 12 12 13 13 0.998591786 -0.006207443 GO:0003674///molecular_function+++GO:0017124///SH3 domain binding GO:0008150///biological_process 50797 50797 'Copb2' mRNA 2394 2505 2482 43.17 44.45 47.48 64.02 63.24 61.81 45.03333333 63.02333333 4085 3941 3819 2460.333333 3948.333333 1.38E-24 0.669352673 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005080///protein kinase C binding+++GO:0005198///structural molecule activity "GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:1901998///toxin transport" 50798 50798 'Gne' mRNA 808 882 907 7.8 8.32 9.24 6.13 5.63 6.13 8.453333333 5.963333333 738 664 714 865.6666667 705.3333333 0.004781978 -0.310119802 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0005524///ATP binding+++GO:0008761///UDP-N-acetylglucosamine 2-epimerase activity+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding" GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0046835///carbohydrate phosphorylation 50799 50799 'Slc25a13' mRNA 338 353 347 6.18 6.35 6.63 5.53 6.53 6.38 6.386666667 6.146666667 356 403 397 346 385.3333333 0.380155758 0.144196386 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0003333///amino acid transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0006810///transport+++GO:0015810///aspartate transmembrane transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0045333///cellular respiration+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0070778///L-aspartate transmembrane transport 50817 50817 'Capn15' mRNA 933 933 912 10.2 10 10.81 7.81 7.41 7.04 10.33666667 7.42 813 762 723 926 766 0.003689009 -0.286216935 GO:0005737///cytoplasm GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 50849 50849 'Rnf10' mRNA 3562 3492 2009 62.67 60.45 37.52 36.58 51.19 48.21 53.54666667 45.32666667 2393 3270 3053 3021 2905.333333 0.886760823 -0.052112446 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0010626///negative regulation of Schwann cell proliferation+++GO:0031643///positive regulation of myelination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051865///protein autoubiquitination+++GO:0099527///postsynapse to nucleus signaling pathway" 50850 50850 'Spast' mRNA 365.75 426.76 353.72 4.16 4.72 4.18 4.02 3.84 3.86 4.353333333 3.906666667 409.41 384.35 384.63 382.0766667 392.7966667 0.863090843 0.03099289 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0071782///endoplasmic reticulum tubular network+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding GO:0000281///mitotic cytokinesis+++GO:0001578///microtubule bundle formation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0008089///anterograde axonal transport+++GO:0008152///metabolic process+++GO:0010458///exit from mitosis+++GO:0019896///axonal transport of mitochondrion+++GO:0030154///cell differentiation+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031468///nuclear envelope reassembly+++GO:0032467///positive regulation of cytokinesis+++GO:0032506///cytokinetic process+++GO:0034214///protein hexamerization+++GO:0051013///microtubule severing+++GO:0051228///mitotic spindle disassembly+++GO:0051260///protein homooligomerization+++GO:0051301///cell division+++GO:0090148///membrane fission 50868 50868 'Keap1' mRNA 1757 1978 1630 29.81 33.18 29.71 26.6 26.7 25.57 30.9 26.29 1776 1750 1671 1788.333333 1732.333333 0.575937352 -0.055073484 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05200///Pathways in cancer+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016234///inclusion body+++GO:0030496///midbody+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0097718///disordered domain specific binding "GO:0001701///in utero embryonic development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010506///regulation of autophagy+++GO:0010629///negative regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0034599///cellular response to oxidative stress+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0045604///regulation of epidermal cell differentiation+++GO:0071322///cellular response to carbohydrate stimulus+++GO:0071353///cellular response to interleukin-4" 50873 50873 'Prkn' mRNA 866.61 728.76 849.83 21.66 16.81 22.61 24.99 27.07 26.69 20.36 26.25 765.22 786.45 789.16 815.0666667 780.2766667 0.594945199 -0.076279436 04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000139///Golgi membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016235///aggresome+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097708///intracellular vesicle+++GO:0098793///presynapse+++GO:0099073///mitochondrion-derived vesicle+++GO:1990452///Parkin-FBXW7-Cul1 ubiquitin ligase complex GO:0001664///G protein-coupled receptor binding+++GO:0003714///transcription corepressor activity+++GO:0003779///actin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0015631///tubulin binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0043130///ubiquitin binding+++GO:0043274///phospholipase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097602///cullin family protein binding+++GO:1990381///ubiquitin-specific protease binding+++GO:1990444///F-box domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0000266///mitochondrial fission+++GO:0000422///autophagy of mitochondrion+++GO:0000423///mitophagy+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001963///synaptic transmission, dopaminergic+++GO:0001964///startle response+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006914///autophagy+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0007612///learning+++GO:0007626///locomotory behavior+++GO:0008344///adult locomotory behavior+++GO:0010468///regulation of gene expression+++GO:0010498///proteasomal protein catabolic process+++GO:0010506///regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0019538///protein metabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032092///positive regulation of protein binding+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033132///negative regulation of glucokinase activity+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042053///regulation of dopamine metabolic process+++GO:0042415///norepinephrine metabolic process+++GO:0042417///dopamine metabolic process+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043388///positive regulation of DNA binding+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0044257///cellular protein catabolic process+++GO:0044828///negative regulation by host of viral genome replication+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0046676///negative regulation of insulin secretion+++GO:0046928///regulation of neurotransmitter secretion+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050821///protein stabilization+++GO:0051582///positive regulation of neurotransmitter uptake+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0051646///mitochondrion localization+++GO:0051865///protein autoubiquitination+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0055069///zinc ion homeostasis+++GO:0060548///negative regulation of cell death+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0070050///neuron cellular homeostasis+++GO:0070534///protein K63-linked ubiquitination+++GO:0070585///protein localization to mitochondrion+++GO:0070842///aggresome assembly+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090258///negative regulation of mitochondrial fission+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0097237///cellular response to toxic substance+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0099074///mitochondrion to lysosome transport+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1901215///negative regulation of neuron death+++GO:1901526///positive regulation of mitophagy+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1902283///negative regulation of primary amine oxidase activity+++GO:1902530///positive regulation of protein linear polyubiquitination+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903542///negative regulation of exosomal secretion+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:1903861///positive regulation of dendrite extension+++GO:1904049///negative regulation of spontaneous neurotransmitter secretion+++GO:1904881///cellular response to hydrogen sulfide+++GO:1905232///cellular response to L-glutamate+++GO:1905366///negative regulation of intralumenal vesicle formation+++GO:1905477///positive regulation of protein localization to membrane+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2001171///positive regulation of ATP biosynthetic process" 50874 50874 'Tmod4' mRNA 127.96 137.32 147.18 3.22 2.71 3.82 1.92 1.97 1.65 3.25 1.846666667 74.16 80.45 65.05 137.4866667 73.22 2.40E-04 -0.922462107 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0030016///myofibril GO:0003779///actin binding+++GO:0005523///tropomyosin binding+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0030239///myofibril assembly+++GO:0051694///pointed-end actin filament capping 50875 50875 'Tmod3' mRNA 1424.59 1448.21 1343.97 21.53 21.55 21.56 43.58 43.98 43.69 21.54666667 43.75 3316.01 3268.87 3220 1405.59 3268.293333 5.64E-80 1.206893733 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0030016///myofibril+++GO:0030027///lamellipodium+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0005523///tropomyosin binding+++GO:0051011///microtubule minus-end binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0030239///myofibril assembly+++GO:0048821///erythrocyte development+++GO:0051271///negative regulation of cellular component movement+++GO:0051694///pointed-end actin filament capping+++GO:1901992///positive regulation of mitotic cell cycle phase transition 50876 50876 'Tmod2' mRNA 1220 1221 1127 6.48 6.37 6.34 4.18 3.9 4.27 6.396666667 4.116666667 906 829 899 1189.333333 878 1.74E-07 -0.44909189 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0030016///myofibril+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005523///tropomyosin binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0007270///neuron-neuron synaptic transmission+++GO:0007611///learning or memory+++GO:0030239///myofibril assembly+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0051694///pointed-end actin filament capping 50877 50877 'Neu3' mRNA 205.4 184.25 178.76 3.33 2.94 3.08 3.08 2.79 3.52 3.116666667 3.13 218.51 192.98 241.78 189.47 217.7566667 0.377981462 0.187959872 00511///Other glycan degradation+++00600///Sphingolipid metabolism GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane "GO:0004308///exo-alpha-sialidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016997///alpha-sialidase activity+++GO:0052794///exo-alpha-(2->3)-sialidase activity+++GO:0052795///exo-alpha-(2->6)-sialidase activity+++GO:0052796///exo-alpha-(2->8)-sialidase activity" GO:0005975///carbohydrate metabolic process+++GO:0006629///lipid metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process+++GO:0016042///lipid catabolic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:1900186///negative regulation of clathrin-dependent endocytosis 50878 50878 'Stag3' mRNA 45 40 27 0.55 0.65 0.46 0.35 0.56 0.69 0.553333333 0.533333333 29 44 36 37.33333333 36.33333333 0.944041344 -0.040004848 04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0000802///transverse filament+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0008278///cohesin complex+++GO:0030893///meiotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex" GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0007065///male meiosis sister chromatid cohesion+++GO:0007066///female meiosis sister chromatid cohesion+++GO:0007129///synapsis+++GO:0034502///protein localization to chromosome+++GO:0051321///meiotic cell cycle 50880 50880 'Scly' mRNA 408 369 261 10.37 9.23 7.02 12.41 12.83 11.54 8.873333333 12.26 559 564 504 346 542.3333333 1.48E-05 0.643733317 00450///Selenocompound metabolism GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:1902494///catalytic complex "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0009000///selenocysteine lyase activity+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0042803///protein homodimerization activity+++GO:0046983///protein dimerization activity+++GO:0070279///vitamin B6 binding" GO:0001887///selenium compound metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0016261///selenocysteine catabolic process+++GO:0032868///response to insulin+++GO:1900408///negative regulation of cellular response to oxidative stress 50883 50883 'Chek2' mRNA 32.33 40.3 34.63 0.72 0.9 0.9 3.89 4.32 4.38 0.84 4.196666667 188.9 202.59 201.82 35.75333333 197.77 3.55E-23 2.469361865 04110///Cell cycle+++04115///p53 signaling pathway+++04218///Cellular senescence+++05166///Human T-cell leukemia virus 1 infection "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016605///PML body" "GO:0000166///nucleotide binding+++GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0016779///nucleotidyltransferase activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding" "GO:0000077///DNA damage checkpoint+++GO:0000085///mitotic G2 phase+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006975///DNA damage induced protein phosphorylation+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008654///phospholipid biosynthetic process+++GO:0010332///response to gamma radiation+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0035690///cellular response to drug+++GO:0042176///regulation of protein catabolic process+++GO:0042770///signal transduction in response to DNA damage+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0044257///cellular protein catabolic process+++GO:0044773///mitotic DNA damage checkpoint+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071480///cellular response to gamma radiation+++GO:0072428///signal transduction involved in intra-S DNA damage checkpoint+++GO:0090307///mitotic spindle assembly+++GO:0140042///lipid droplet formation+++GO:1903416///response to glycoside+++GO:1903926///cellular response to bisphenol A+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:2000210///positive regulation of anoikis" 50884 50884 'Nckap1' mRNA 1500 1611 1472 18.37 19.41 19.14 15.54 14.87 14.63 18.97333333 15.01333333 1460 1365 1332 1527.666667 1385.666667 0.070148067 -0.152362611 04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0031209///SCAR complex+++GO:0031258///lamellipodium membrane+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0098794///postsynapse GO:0005515///protein binding+++GO:0031267///small GTPase binding "GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0007354///zygotic determination of anterior/posterior axis, embryo+++GO:0007492///endoderm development+++GO:0008078///mesodermal cell migration+++GO:0010172///embryonic body morphogenesis+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030903///notochord development+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0032880///regulation of protein localization+++GO:0035050///embryonic heart tube development+++GO:0042074///cell migration involved in gastrulation+++GO:0045175///basal protein localization+++GO:0045176///apical protein localization+++GO:0048339///paraxial mesoderm development+++GO:0048340///paraxial mesoderm morphogenesis+++GO:0048570///notochord morphogenesis+++GO:0048617///embryonic foregut morphogenesis+++GO:0048812///neuron projection morphogenesis+++GO:0050821///protein stabilization+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation" 50887 50887 'Hmgn5' mRNA 412 399 380 12.37 11.8 12.1 11.78 13.67 13.54 12.09 12.99666667 451 511 502 397 488 0.033296201 0.287860717 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006749///glutathione metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0043066///negative regulation of apoptotic process 50905 50905 'Il17rb' mRNA 1892 1935 1948 53.13 52.49 58.76 40.11 40.45 39.72 54.79333333 40.09333333 1622 1591 1566 1925 1593 2.35E-04 -0.286123575 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0072686///mitotic spindle GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0030368///interleukin-17 receptor activity GO:0019221///cytokine-mediated signaling pathway+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0050729///positive regulation of inflammatory response 50907 50907 'Preb' mRNA 1565 1772 1730 22.16 23.37 24.21 27.91 25.14 25.3 23.24666667 26.11666667 2254 2135 2001 1689 2130 1.61E-04 0.321047567 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0051020///GTPase binding GO:0003400///regulation of COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048208///COPII vesicle coating+++GO:0050790///regulation of catalytic activity 50908 50908 'C1s1' mRNA 90.77 91.45 152.69 1.72 1.7 3.06 7.51 7.58 7.36 2.16 7.483333333 459.11 451.57 436.2 111.6366667 448.96 4.46E-23 1.99206219 04610///Complement and coagulation cascades+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response" 50909 50909 'C1ra' mRNA 338.99 317.92 315.58 6.78 6.26 6.7 16.13 15.06 15.05 6.58 15.41333333 927.18 845.49 838.01 324.1633333 870.2266667 7.86E-39 1.415634334 04145///Phagosome+++04610///Complement and coagulation cascades+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005615///extracellular space+++GO:0072562///blood microparticle GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0031638///zymogen activation+++GO:0045087///innate immune response" 50911 50911 'Exosc9' mRNA 506.04 605.16 518.2 18.29 21.57 19.87 25.88 27.6 25.08 19.91 26.18666667 822.56 856.12 771.45 543.1333333 816.71 1.60E-07 0.578127976 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003723///RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0016075///rRNA catabolic process+++GO:0030307///positive regulation of cell growth+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034473///U1 snRNA 3'-end processing+++GO:0034475///U4 snRNA 3'-end processing+++GO:0034476///U5 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071028///nuclear mRNA surveillance+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process" 50912 50912 'Exosc10' mRNA 970 978 949 19.14 19.06 19.91 17.46 16.97 16.68 19.37 17.03666667 1020 964 943 965.6666667 975.6666667 0.989729013 0.002571926 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035327///transcriptionally active chromatin GO:0000166///nucleotide binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004532///exoribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000460///maturation of 5.8S rRNA+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0044237///cellular metabolic process+++GO:0071028///nuclear mRNA surveillance+++GO:0071034///CUT catabolic process+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071036///nuclear polyadenylation-dependent snoRNA catabolic process+++GO:0071037///nuclear polyadenylation-dependent snRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071039///nuclear polyadenylation-dependent CUT catabolic process+++GO:0071040///nuclear polyadenylation-dependent antisense transcript catabolic process+++GO:0071044///histone mRNA catabolic process+++GO:0071048///nuclear retention of unspliced pre-mRNA at the site of transcription+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing+++GO:1904872///regulation of telomerase RNA localization to Cajal body" 50914 50914 'Olig1' mRNA 0 1 0 0 0.03 0 0 0.07 0.02 0.01 0.03 0 3 1 0.333333333 1.333333333 0.606866237 1.902873344 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0014003///oligodendrocyte development+++GO:0030182///neuron differentiation+++GO:0048663///neuron fate commitment+++GO:0048709///oligodendrocyte differentiation" 50915 50915 'Grb14' mRNA 1990 2193 1917 60.63 65.12 61.5 31.45 31.34 31.53 62.41666667 31.44 1215 1185 1176 2033.333333 1192 3.40E-26 -0.780836089 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0030971///receptor tyrosine kinase binding+++GO:0051219///phosphoprotein binding" GO:0007165///signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0032869///cellular response to insulin stimulus+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:1904145///negative regulation of meiotic cell cycle process involved in oocyte maturation 50917 50917 'Galns' mRNA 229 268 209 5.21 5.92 5.02 18.4 18.57 18.76 5.383333333 18.57666667 958 927 953 235.3333333 946 5.29E-69 1.998165997 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005764///lysosome GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0043890///N-acetylgalactosamine-6-sulfatase activity+++GO:0046872///metal ion binding 50918 50918 'Myadm' mRNA 1879 1921 1853 35.69 35.86 37.48 71.77 70.33 66.94 36.34333333 69.68 4308 4115 3888 1884.333333 4103.666667 1.16E-66 1.110548309 GO:0001726///ruffle+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0045121///membrane raft GO:0001933///negative regulation of protein phosphorylation+++GO:0010629///negative regulation of gene expression+++GO:0030335///positive regulation of cell migration+++GO:0030837///negative regulation of actin filament polymerization+++GO:0031579///membrane raft organization+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0061028///establishment of endothelial barrier+++GO:0072659///protein localization to plasma membrane+++GO:0090038///negative regulation of protein kinase C signaling+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 50926 50926 'Hnrnpdl' mRNA 2696 2776 2504.78 51.54 52.35 51.05 41.71 34.87 38.44 51.64666667 38.34 2511.9 2047.93 2255.79 2658.926667 2271.873333 0.00188257 -0.239506854 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0008143///poly(A) binding+++GO:0034046///poly(G) binding GO:0010468///regulation of gene expression+++GO:0016071///mRNA metabolic process 50927 50927 'Nasp' mRNA 665.65 599.75 566.57 12.57 11.34 10.71 18.59 17.23 17.22 11.54 17.68 1389.15 1300.78 1299.15 610.6566667 1329.693333 3.53E-35 1.112906504 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0044877///protein-containing complex binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001824///blastocyst development+++GO:0006260///DNA replication+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0007049///cell cycle+++GO:0008584///male gonad development+++GO:0015031///protein transport+++GO:0033574///response to testosterone+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0043486///histone exchange 50928 50928 'Klrg1' mRNA 7 5 6 0.31 0.22 0.28 0.38 0.39 0.55 0.27 0.44 10 10 14 6 11.33333333 0.343335672 0.905483611 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0030246///carbohydrate binding GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0045087///innate immune response 50930 50930 'Tnfsf14' mRNA 2 2 0 0.06 0.06 0 0.93 1.29 0.97 0.04 1.063333333 35 47 35 1.333333333 39 8.71E-08 4.868947406 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04064///NF-kappa B signaling pathway+++05168///Herpes simplex virus 1 infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0006915///apoptotic process+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0031295///T cell costimulation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045663///positive regulation of myoblast differentiation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901741///positive regulation of myoblast fusion 50931 50931 'Il27ra' mRNA 5 12 7.45 0.14 0.25 0.17 1.1 0.76 0.78 0.186666667 0.88 50 38 37.88 8.15 41.96 2.07E-05 2.370555871 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042022///interleukin-12 receptor complex+++GO:0043235///receptor complex+++GO:0072536///interleukin-23 receptor complex GO:0004896///cytokine receptor activity+++GO:0005143///interleukin-12 receptor binding+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0042019///interleukin-23 binding+++GO:0045509///interleukin-27 receptor activity GO:0002692///negative regulation of cellular extravasation+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0002829///negative regulation of type 2 immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0050830///defense response to Gram-positive bacterium+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:2000317///negative regulation of T-helper 17 type immune response+++GO:2000408///negative regulation of T cell extravasation 50932 50932 'Mink1' mRNA 1666 1762 944 17.89 18.54 10.63 8.98 7.96 8.49 15.68666667 8.476666667 979 832 886 1457.333333 899 0.008823378 -0.696766014 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0001952///regulation of cell-matrix adhesion+++GO:0006468///protein phosphorylation+++GO:0007268///chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0016310///phosphorylation+++GO:0022407///regulation of cell-cell adhesion+++GO:0030334///regulation of cell migration+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031532///actin cytoskeleton reorganization+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0045060///negative thymic T cell selection+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0070050///neuron cellular homeostasis+++GO:1900745///positive regulation of p38MAPK cascade+++GO:2000311///regulation of AMPA receptor activity 50933 50933 'Uchl3' mRNA 253.81 245.82 275.94 17.5 16.64 19.69 39.11 37.58 40.83 17.94333333 39.17333333 644.81 605.16 651.48 258.5233333 633.8166667 1.06E-23 1.283026995 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0043130///ubiquitin binding+++GO:0101005///ubiquitinyl hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007628///adult walking behavior+++GO:0016579///protein deubiquitination+++GO:0030163///protein catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0042755///eating behavior+++GO:0045600///positive regulation of fat cell differentiation+++GO:0060041///retina development in camera-type eye 50934 50934 'Slc7a8' mRNA 4338 4201 4247 61.96 57.07 63.99 89.23 83.53 87.03 61.00666667 86.59666667 7506 6799 7202 4262 7169 6.30E-36 0.736842769 04974///Protein digestion and absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane GO:0005275///amine transmembrane transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015187///glycine transmembrane transporter activity+++GO:0015190///L-leucine transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0019534///toxin transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015695///organic cation transport+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0015816///glycine transport+++GO:0015820///leucine transport+++GO:0015827///tryptophan transport+++GO:0015829///valine transport+++GO:0015837///amine transport+++GO:0035524///proline transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:0089718///amino acid import across plasma membrane+++GO:0098713///leucine import across plasma membrane+++GO:1901998///toxin transport+++GO:1903801///L-leucine import across plasma membrane+++GO:1904273///L-alanine import across plasma membrane 50935 50935 'St6galnac6' mRNA 254 226 216 6.03 5.23 5.41 7.74 8.73 9.75 5.556666667 8.74 371 416 454 232 413.6666667 5.68E-08 0.825183662 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006677///glycosylceramide metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:0009100///glycoprotein metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0009988///cell-cell recognition+++GO:0097503///sialylation 50995 50995 'Uba2' mRNA 1659 1781 1776 35.83 38.32 40.64 42.93 40.68 39.95 38.26333333 41.18666667 2268 2105 2049 1738.666667 2140.666667 3.61E-04 0.286296259 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031510///SUMO activating enzyme complex "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016740///transferase activity+++GO:0019948///SUMO activating enzyme activity+++GO:0032183///SUMO binding+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0010628///positive regulation of gene expression+++GO:0016925///protein sumoylation+++GO:0021759///globus pallidus development+++GO:0021772///olfactory bulb development+++GO:0021800///cerebral cortex tangential migration+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0021846///cell proliferation in forebrain+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0032446///protein modification by small protein conjugation+++GO:0033235///positive regulation of protein sumoylation+++GO:0042127///regulation of cell proliferation+++GO:0044241///lipid digestion+++GO:0046622///positive regulation of organ growth+++GO:0048484///enteric nervous system development+++GO:0072148///epithelial cell fate commitment" 50996 50996 'Pdcd7' mRNA 182 190 130 4.14 4.25 3.13 3.2 2.93 3.33 3.84 3.153333333 162 145 163 167.3333333 156.6666667 0.717043226 -0.100796904 GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex GO:0003674///molecular_function GO:0006356///regulation of transcription by RNA polymerase I+++GO:0006915///apoptotic process+++GO:0051384///response to glucocorticoid+++GO:0070234///positive regulation of T cell apoptotic process+++GO:2001235///positive regulation of apoptotic signaling pathway 50997 50997 'Mpp2' mRNA 615 653 577 8.08 8.41 8.07 4.06 4.61 3.37 8.186666667 4.013333333 354 394 285 615 344.3333333 4.82E-10 -0.846457263 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction+++GO:0032590///dendrite membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0044224///juxtaparanode region of axon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099031///anchored component of postsynaptic density membrane+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019900///kinase binding+++GO:0019903///protein phosphatase binding+++GO:0030165///PDZ domain binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0098919///structural constituent of postsynaptic density GO:0007268///chemical synaptic transmission+++GO:0019233///sensory perception of pain+++GO:0035865///cellular response to potassium ion+++GO:0043113///receptor clustering+++GO:0045161///neuronal ion channel clustering+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0051260///protein homooligomerization+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0099562///maintenance of postsynaptic density structure+++GO:0099641///anterograde axonal protein transport+++GO:0099642///retrograde axonal protein transport+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 51786 51786 'Cpsf2' mRNA 687.82 751.19 723.65 6.09 6.57 6.9 8.98 8.37 8.54 6.52 8.63 1102.82 1004.52 1026.66 720.8866667 1044.666667 3.90E-08 0.522424655 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0003723///RNA binding GO:0006378///mRNA polyadenylation+++GO:0006379///mRNA cleavage+++GO:0006397///mRNA processing+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0098789///pre-mRNA cleavage required for polyadenylation 51788 51788 'H2az1' mRNA 3749.52 3733.86 3766.93 220.84 217.33 235.42 352.95 381.69 358.19 224.53 364.2766667 6875 7246.81 6742.94 3750.103333 6954.916667 1.19E-43 0.879012573 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0007275///multicellular organism development+++GO:0031507///heterochromatin assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus 51789 51789 'Tnk2' mRNA 671 673 442 10.53 10.32 7.77 5.54 4.9 5.63 9.54 5.356666667 392 359 405 595.3333333 385.3333333 1.85E-05 -0.631359767 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0070436///Grb2-EGFR complex+++GO:0097268///cytoophidium GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050699///WW domain binding GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007286///spermatid development+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0045087///innate immune response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000369///regulation of clathrin-dependent endocytosis 51791 51791 'Rgs14' mRNA 18 18 23 0.43 0.42 0.58 4.61 4.93 4.1 0.476666667 4.546666667 223 233 192 19.66666667 216 5.77E-34 3.443550177 04015///Rap1 signaling pathway GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0001965///G-protein alpha-subunit binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0032794///GTPase activating protein binding GO:0000278///mitotic cell cycle+++GO:0006913///nucleocytoplasmic transport+++GO:0006979///response to oxidative stress+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0008542///visual learning+++GO:0009968///negative regulation of signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050769///positive regulation of neurogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051301///cell division+++GO:0060291///long-term synaptic potentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade 51792 51792 'Ppp2r1a' mRNA 6596 6755 6623 164.42 165.82 175.13 172.95 176.49 175.73 168.4566667 175.0566667 7979 7950 7848 6658 7925.666667 2.67E-05 0.239104654 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++04730///Long-term depression+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection "GO:0000159///protein phosphatase type 2A complex+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008287///protein serine/threonine phosphatase complex+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse" GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0046982///protein heterodimerization activity+++GO:1990405///protein antigen binding "GO:0006470///protein dephosphorylation+++GO:0007059///chromosome segregation+++GO:0007143///female meiotic nuclear division+++GO:0050790///regulation of catalytic activity+++GO:0051232///meiotic spindle elongation+++GO:0051306///mitotic sister chromatid separation+++GO:0051754///meiotic sister chromatid cohesion, centromeric+++GO:0065003///protein-containing complex assembly+++GO:0070262///peptidyl-serine dephosphorylation+++GO:1903538///regulation of meiotic cell cycle process involved in oocyte maturation+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand" 51793 51793 'Ddah2' mRNA 1456 1505 1391 63.01 64.47 64.21 88.08 84.31 94.58 63.89666667 88.99 2328 2176 2416 1450.666667 2306.666667 5.05E-20 0.657822731 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0016403///dimethylargininase activity+++GO:0016597///amino acid binding+++GO:0016787///hydrolase activity GO:0000052///citrulline metabolic process+++GO:0006525///arginine metabolic process+++GO:0006527///arginine catabolic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process 51795 51795 'Srpx' mRNA 46 43 54 1.09 0.97 1.31 3.61 3.37 4.08 1.123333333 3.686666667 181 165 197 47.66666667 181 8.80E-15 1.909479616 GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum GO:0005515///protein binding GO:0001845///phagolysosome assembly+++GO:0006914///autophagy+++GO:0034976///response to endoplasmic reticulum stress+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 51796 51796 'Srrm1' mRNA 3618 3561 3115 38.46 36.7 34.09 25.33 25.18 24.98 36.41666667 25.16333333 2483 2445 2389 3431.333333 2439 1.45E-15 -0.501870135 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome GO:0003677///DNA binding+++GO:0003723///RNA binding "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 51797 51797 'Ctps' mRNA 337 306 291 6.86 6.1 6.26 21.6 19.55 18.79 6.406666667 19.98 1218 1074 1025 311.3333333 1105.666667 2.90E-63 1.816552077 00240///Pyrimidine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097268///cytoophidium GO:0000166///nucleotide binding+++GO:0003883///CTP synthase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0019856///pyrimidine nucleobase biosynthetic process+++GO:0042098///T cell proliferation+++GO:0042100///B cell proliferation+++GO:0044210///'de novo' CTP biosynthetic process 51798 51798 'Ech1' mRNA 3798 3950 3586 207.2 212.89 207.57 174.84 187.16 175.39 209.22 179.13 3677 3838 3566 3778 3693.666667 0.595403863 -0.042783037 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome "GO:0003824///catalytic activity+++GO:0016853///isomerase activity+++GO:0051750///delta3,5-delta2,4-dienoyl-CoA isomerase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation 51799 51799 'Rundc3a' mRNA 216 239 180 5.66 6.18 4.97 1.77 1.56 1.87 5.603333333 1.733333333 79 74 81 211.6666667 78 6.21E-12 -1.447667912 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0010753///positive regulation of cGMP-mediated signaling 51800 51800 'Bok' mRNA 209 241 211 7.88 8.96 8.44 7.35 7.6 6.82 8.426666667 7.256666667 224 226 201 220.3333333 217 0.882154509 -0.03265197 04214///Apoptosis - fly+++04215///Apoptosis - multiple species GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031966///mitochondrial membrane+++GO:0032588///trans-Golgi network membrane+++GO:0033106///cis-Golgi network membrane+++GO:0055038///recycling endosome membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0051400///BH domain binding GO:0001836///release of cytochrome c from mitochondria+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006921///cellular component disassembly involved in execution phase of apoptosis+++GO:0007420///brain development+++GO:0008584///male gonad development+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0010506///regulation of autophagy+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048709///oligodendrocyte differentiation+++GO:0051259///protein complex oligomerization+++GO:0051402///neuron apoptotic process+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051902///negative regulation of mitochondrial depolarization+++GO:0060546///negative regulation of necroptotic process+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1901382///regulation of chorionic trophoblast cell proliferation+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903899///positive regulation of PERK-mediated unfolded protein response+++GO:1904708///regulation of granulosa cell apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 51801 51801 'Ramp1' mRNA 504 542 445 11.08 11.64 10.48 12.31 11.63 12.6 11.06666667 12.18 648 593 636 497 625.6666667 0.005343576 0.322723837 04270///Vascular smooth muscle contraction GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0150056///amylin receptor complex 1+++GO:1990406///CGRP receptor complex GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity+++GO:1990407///calcitonin gene-related peptide binding GO:0001525///angiogenesis+++GO:0006816///calcium ion transport+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0031623///receptor internalization+++GO:0032092///positive regulation of protein binding+++GO:0032870///cellular response to hormone stimulus+++GO:0060050///positive regulation of protein glycosylation+++GO:0072659///protein localization to plasma membrane+++GO:0097647///amylin receptor signaling pathway+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway 51810 51810 'Hnrnpu' mRNA 5318.44 5284.53 2571 45.32 44.96 20.22 23.69 21.6 28.92 36.83333333 24.73666667 3422.89 3085.07 3837.7 4391.323333 3448.553333 0.360275167 -0.345025901 03040///Spliceosome "GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005694///chromosome+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0009986///cell surface+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0030496///midbody+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0072686///mitotic spindle+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0098577///inactive sex chromosome+++GO:0099524///postsynaptic cytosol+++GO:1990023///mitotic spindle midzone+++GO:1990498///mitotic spindle microtubule+++GO:1990904///ribonucleoprotein complex" GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001097///TFIIH-class transcription factor complex binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008143///poly(A) binding+++GO:0017069///snRNA binding+++GO:0017130///poly(C) RNA binding+++GO:0031490///chromatin DNA binding+++GO:0034046///poly(G) binding+++GO:0036002///pre-mRNA binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0070034///telomerase RNA binding+++GO:0099122///RNA polymerase II C-terminal domain binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006325///chromatin organization+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007346///regulation of mitotic cell cycle+++GO:0008380///RNA splicing+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010628///positive regulation of gene expression+++GO:0016071///mRNA metabolic process+++GO:0030154///cell differentiation+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032922///circadian regulation of gene expression+++GO:0033673///negative regulation of kinase activity+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048255///mRNA stabilization+++GO:0048511///rhythmic process+++GO:0051301///cell division+++GO:0051457///maintenance of protein location in nucleus+++GO:0055013///cardiac muscle cell development+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0098963///dendritic transport of messenger ribonucleoprotein complex+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902275///regulation of chromatin organization+++GO:1902425///positive regulation of attachment of mitotic spindle microtubules to kinetochore+++GO:1902889///protein localization to spindle microtubule+++GO:1990280///RNA localization to chromatin+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1990845///adaptive thermogenesis+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity+++GO:2000648///positive regulation of stem cell proliferation+++GO:2000737///negative regulation of stem cell differentiation" 51811 51811 'Clec4f' mRNA 17 17 13 0.4 0.39 0.3 0 0 0.06 0.363333333 0.02 0 0 3 15.66666667 1 0.001173113 -3.974033336 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005534///galactose binding+++GO:0030246///carbohydrate binding+++GO:0051861///glycolipid binding GO:0006897///endocytosis+++GO:0044419///interspecies interaction between organisms+++GO:0051132///NK T cell activation 51812 51812 'Mcrs1' mRNA 1429 1561 1425 42.67 45.9 45.38 44.09 45.07 42.51 44.65 43.89 1683 1683 1574 1471.666667 1646.666667 0.07503524 0.15094228 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005844///polysome+++GO:0030425///dendrite+++GO:0031011///Ino80 complex+++GO:0043204///perikaryon+++GO:0044545///NSL complex+++GO:0071339///MLL1 complex GO:0002151///G-quadruplex RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0010521///telomerase inhibitor activity+++GO:0034046///poly(G) binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051974///negative regulation of telomerase activity+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1904751///positive regulation of protein localization to nucleolus 51813 51813 'Ccnc' mRNA 626.55 661.28 611.43 13.83 15.61 15.11 16.67 19.02 17.68 14.85 17.79 743.26 782.19 775.1 633.0866667 766.85 0.012601218 0.266600595 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0090209///negative regulation of triglyceride metabolic process 51869 51869 'Rif1' mRNA 1111 1124 988 4.49 4.47 4.24 3.11 3.17 3.46 4.4 3.246666667 887 881 956 1074.333333 908 0.007128679 -0.252194857 04550///Signaling pathways regulating pluripotency of stem cells "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0031965///nuclear membrane+++GO:0035861///site of double-strand break+++GO:0051233///spindle midzone" GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000723///telomere maintenance+++GO:0006281///DNA repair+++GO:0006348///chromatin silencing at telomere+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0019827///stem cell population maintenance+++GO:0031509///telomeric heterochromatin assembly+++GO:0043247///telomere maintenance in response to DNA damage+++GO:0045830///positive regulation of isotype switching+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 51875 51875 'Tmem141' mRNA 536 554 546 40.07 40.34 43.13 45.08 48.12 48.04 41.18 47.08 704 725 726 545.3333333 718.3333333 4.08E-04 0.385627367 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 51885 51885 'Tubgcp4' mRNA 878.22 841.34 810.15 11.12 10.47 10.88 12.1 11.6 12 10.82333333 11.9 1100.02 1030.42 1057.45 843.2366667 1062.63 3.69E-04 0.321940889 GO:0000922///spindle pole+++GO:0000923///equatorial microtubule organizing center+++GO:0000930///gamma-tubulin complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0055037///recycling endosome GO:0043015///gamma-tubulin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007020///microtubule nucleation+++GO:0031122///cytoplasmic microtubule organization+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle 51886 51886 'Fubp1' mRNA 2576 2713 2559 30.1 31.41 32.53 26.89 25.84 24.54 31.34666667 25.75666667 2633 2359 2265 2616 2419 0.11153726 -0.125701621 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0048103///somatic stem cell division+++GO:0048588///developmental cell growth+++GO:0071425///hematopoietic stem cell proliferation+++GO:1900149///positive regulation of Schwann cell migration" 51897 51897 'Atg13' mRNA 1779 1784 1808 27.03 26.75 29.13 19.01 18.41 16.19 27.63666667 17.87 1434 1361 1186 1790.333333 1327 5.01E-07 -0.445731637 04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0034451///centriolar satellite+++GO:1990316///Atg1/ULK1 kinase complex GO:0003674///molecular_function+++GO:0004518///nuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding GO:0000045///autophagosome assembly+++GO:0000423///mitophagy+++GO:0006914///autophagy+++GO:0008150///biological_process+++GO:0034497///protein localization to phagophore assembly site+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0098780///response to mitochondrial depolarisation 51902 51902 'Rnf24' mRNA 302.49 312.67 268.42 2.89 2.94 2.72 1.84 1.22 1.86 2.85 1.64 221.61 143.67 217.13 294.5266667 194.1366667 0.001165135 -0.614359145 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 51938 51938 'Ccdc39' mRNA 1245.22 1258.35 1130.9 18.92 20.25 18.44 2.33 1.79 2.09 19.20333333 2.07 145.47 114.18 119.63 1211.49 126.4266667 5.96E-162 -3.27610486 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function GO:0001947///heart looping+++GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0030317///flagellated sperm motility+++GO:0030324///lung development+++GO:0035469///determination of pancreatic left/right asymmetry+++GO:0036159///inner dynein arm assembly+++GO:0044458///motile cilium assembly+++GO:0051649///establishment of localization in cell+++GO:0060285///cilium-dependent cell motility+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0061512///protein localization to cilium+++GO:0061966///establishment of left/right asymmetry+++GO:0070286///axonemal dynein complex assembly+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0071910///determination of liver left/right asymmetry+++GO:0090660///cerebrospinal fluid circulation 51944 51944 'Knstrn' mRNA 68 90 72 1.05 1.38 1.25 5.51 5.32 5.14 1.226666667 5.323333333 372 348 335 76.66666667 351.6666667 7.59E-33 2.187025045 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0034451///centriolar satellite+++GO:0035371///microtubule plus-end+++GO:0072686///mitotic spindle" GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0051010///microtubule plus-end binding GO:0000070///mitotic sister chromatid segregation+++GO:0000226///microtubule cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0016477///cell migration+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0071364///cellular response to epidermal growth factor stimulus 51960 51960 'Kctd18' mRNA 297 305 303 5.51 5.52 6.04 6.06 4.46 4.7 5.69 5.073333333 369 271 284 301.6666667 308 0.946257491 0.014754546 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0051260///protein homooligomerization 52004 52004 'Cdk2ap2' mRNA 1746 1625 1631 115.33 106.96 114.31 141.85 149.66 140.3 112.2 143.9366667 2389 2455 2310 1667.333333 2384.666667 8.45E-12 0.504553418 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule GO:0005515///protein binding GO:0070507///regulation of microtubule cytoskeleton organization+++GO:2000035///regulation of stem cell division+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 52009 52009 'Jpt2' mRNA 494 564 667 10.52 11.83 15.07 22.65 23.52 25.92 12.47333333 24.03 1223 1240 1355 575 1272.666667 4.90E-20 1.129096222 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane 52013 52013 'R3hcc1l' mRNA 497 521 521 6.75 6.95 7.5 7.42 6.25 6.4 7.066666667 6.69 629 518 524 513 557 0.484040165 0.104201923 GO:0035145///exon-exon junction complex GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0008150///biological_process 52014 52014 'Nus1' mRNA 385 405 344 4.47 4.63 4.24 6.85 6.47 7.18 4.446666667 6.833333333 679 626 689 378 664.6666667 1.45E-12 0.8043546 00900///Terpenoid backbone biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1904423///dehydrodolichyl diphosphate synthase complex "GO:0004659///prenyltransferase activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0045547///dehydrodolichyl diphosphate synthase activity" GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0006489///dolichyl diphosphate biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0007275///multicellular organism development+++GO:0019408///dolichol biosynthetic process+++GO:0030154///cell differentiation+++GO:0032383///regulation of intracellular cholesterol transport+++GO:0035268///protein mannosylation+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0055092///sterol homeostasis 52020 52020 'Umodl1' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0030414///peptidase inhibitor activity GO:0007338///single fertilization+++GO:0010468///regulation of gene expression+++GO:0042981///regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0048609///multicellular organismal reproductive process+++GO:0052547///regulation of peptidase activity+++GO:0060612///adipose tissue development+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:1990266///neutrophil migration+++GO:2000354///regulation of ovarian follicle development 52023 52023 'Pibf1' mRNA 650.47 613.13 653.95 13.2 12.06 13.92 14.85 14.92 14.49 13.06 14.75333333 844.67 826.49 798.44 639.1833333 823.2 9.33E-04 0.351825815 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0034451///centriolar satellite GO:0005136///interleukin-4 receptor binding GO:0007080///mitotic metaphase plate congression+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042976///activation of Janus kinase activity+++GO:0060271///cilium assembly+++GO:0071539///protein localization to centrosome+++GO:0090307///mitotic spindle assembly+++GO:1905515///non-motile cilium assembly 52024 52024 'Ankrd22' mRNA 173 192 162 5.7 6.24 5.67 1.98 1.88 2.4 5.87 2.086666667 69 64 81 175.6666667 71.33333333 7.98E-09 -1.309829196 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 52028 52028 'Bbs1' mRNA 447 474.36 399 4.23 4.4 3.98 2.14 1.25 1.38 4.203333333 1.59 260 149 163 440.12 190.6666667 2.28E-11 -1.220473369 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0034451///centriolar satellite+++GO:0034464///BBSome+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005102///signaling receptor binding+++GO:0005113///patched binding+++GO:0005119///smoothened binding+++GO:0005515///protein binding+++GO:0051219///phosphoprotein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0001895///retina homeostasis+++GO:0007601///visual perception+++GO:0007608///sensory perception of smell+++GO:0008104///protein localization+++GO:0008594///photoreceptor cell morphogenesis+++GO:0009566///fertilization+++GO:0015031///protein transport+++GO:0016358///dendrite development+++GO:0021591///ventricular system development+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030030///cell projection organization+++GO:0030534///adult behavior+++GO:0035721///intraciliary retrograde transport+++GO:0042048///olfactory behavior+++GO:0042445///hormone metabolic process+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0044255///cellular lipid metabolic process+++GO:0045444///fat cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0048854///brain morphogenesis+++GO:0050896///response to stimulus+++GO:0051216///cartilage development+++GO:0060271///cilium assembly+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:0061351///neural precursor cell proliferation+++GO:0061512///protein localization to cilium+++GO:1905515///non-motile cilium assembly 52033 52033 'Pbk' mRNA 4 2 7 0.16 0.08 0.3 11.95 11.92 14 0.18 12.62333333 364 363 418 4.333333333 381.6666667 8.85E-49 6.448362173 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0034644///cellular response to UV+++GO:0050728///negative regulation of inflammatory response 52036 52036 'Ppp6r3' mRNA 1648 1544 1600 18.13 16.92 18.81 16.58 15.18 15.02 17.95333333 15.59333333 1732 1540 1519 1597.333333 1597 0.895584737 -0.014204813 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0019888///protein phosphatase regulator activity+++GO:0019903///protein phosphatase binding GO:0043666///regulation of phosphoprotein phosphatase activity 52040 52040 'Ppp1r10' mRNA 1706 1756 1512 18.31 18.39 17.32 20.23 18.12 18.21 18.00666667 18.85333333 2039 1755 1794 1658 1862.666667 0.059765437 0.157215599 "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0072357///PTW/PP1 phosphatase complex" GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0046872///metal ion binding GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0032206///positive regulation of telomere maintenance+++GO:0043086///negative regulation of catalytic activity+++GO:1904290///negative regulation of mitotic DNA damage checkpoint 52055 52055 'Rab11fip5' mRNA 1327 1353 1123 16.54 16.53 15.08 22.69 23.47 23.22 16.05 23.12666667 2125 2150 2096 1267.666667 2123.666667 1.01E-22 0.735974519 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031966///mitochondrial membrane+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0031267///small GTPase binding+++GO:0043015///gamma-tubulin binding GO:0015031///protein transport+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0045055///regulated exocytosis+++GO:0070164///negative regulation of adiponectin secretion+++GO:0071346///cellular response to interferon-gamma+++GO:0071468///cellular response to acidic pH+++GO:2000008///regulation of protein localization to cell surface 52064 52064 'Coq5' mRNA 986 1193 1221 28.05 33.44 36.85 26.88 28.59 25.11 32.78 26.86 1086 1128 982 1133.333333 1065.333333 0.442459934 -0.103896707 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0032991///protein-containing complex "GO:0008168///methyltransferase activity+++GO:0008425///2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity+++GO:0016740///transferase activity+++GO:0043333///2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity" GO:0006744///ubiquinone biosynthetic process+++GO:0032259///methylation 52065 52065 'Mfhas1' mRNA 368 309 327 3.04 2.51 2.86 4.01 3.3 4.14 2.803333333 3.816666667 559 450 560 334.6666667 523 6.71E-06 0.630514279 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051721///protein phosphatase 2A binding GO:0002376///immune system process+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0009968///negative regulation of signal transduction+++GO:0030218///erythrocyte differentiation+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043030///regulation of macrophage activation+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0050728///negative regulation of inflammatory response+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1900745///positive regulation of p38MAPK cascade 52076 52076 'Tmem38b' mRNA 272 260 330 5.24 4.93 6.76 9.38 9.42 9.44 5.643333333 9.413333333 560 548 545 287.3333333 551 1.33E-10 0.922168454 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005261///cation channel activity+++GO:0005267///potassium channel activity+++GO:0042802///identical protein binding GO:0001503///ossification+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007029///endoplasmic reticulum organization+++GO:0008654///phospholipid biosynthetic process+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0030282///bone mineralization+++GO:0048286///lung alveolus development+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0060348///bone development+++GO:0060487///lung epithelial cell differentiation+++GO:0061033///secretion by lung epithelial cell involved in lung growth+++GO:0070278///extracellular matrix constituent secretion+++GO:0071313///cellular response to caffeine+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:1903514///release of sequestered calcium ion into cytosol by endoplasmic reticulum 52118 52118 'Pvr' mRNA 139 127 143 2.65 2.38 2.89 5.3 5.92 6.88 2.64 6.033333333 320 349 402 136.3333333 357 2.71E-15 1.376316271 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0009986///cell surface+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0050839///cell adhesion molecule binding GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016477///cell migration+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0060370///susceptibility to T cell mediated cytotoxicity+++GO:0098609///cell-cell adhesion 52120 52120 'Hgsnat' mRNA 1690 1640 1476 34.95 33.38 32.38 29.48 33.56 31.8 33.57 31.61333333 1640 1823 1713 1602 1725.333333 0.299305222 0.098168748 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0015019///heparan-alpha-glucosaminide N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0007041///lysosomal transport+++GO:0051259///protein complex oligomerization 52123 52123 'Agpat5' mRNA 584 606 636 8.25 8.42 9.53 8.7 8.75 8.62 8.733333333 8.69 709 696 680 608.6666667 695 0.143652639 0.177498618 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04072///Phospholipase D signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006629///lipid metabolic process+++GO:0006639///acylglycerol metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process 52132 52132 'Ccdc97' mRNA 1236 1264 1054 22.5 22.69 20.43 21.27 19.69 19.31 21.87333333 20.09 1335 1208 1172 1184.666667 1238.333333 0.62894003 0.054324779 GO:0003674///molecular_function GO:0008150///biological_process 52150 52150 'Kcnk6' mRNA 111.96 116.28 127.64 1.48 1.51 1.79 2.62 2.09 2.76 1.593333333 2.49 229.01 177.95 233.39 118.6266667 213.45 6.23E-05 0.836091144 GO:0005887///integral component of plasma membrane GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0003073///regulation of systemic arterial blood pressure+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0030322///stabilization of membrane potential+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport 52163 52163 'Camk1' mRNA 1520.84 1574.64 1166.98 63.11 64.46 51.38 81.8 121.42 109.34 59.65 104.1866667 2263.99 3278.88 2927.38 1420.82 2823.416667 7.83E-07 0.989582333 04020///Calcium signaling pathway+++04921///Oxytocin signaling pathway+++04925///Aldosterone synthesis and secretion+++05214///Glioma GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008152///metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0032091///negative regulation of protein binding+++GO:0032880///regulation of protein localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043393///regulation of protein binding+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046827///positive regulation of protein export from nucleus+++GO:0050807///regulation of synapse organization+++GO:0051147///regulation of muscle cell differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion+++GO:0060999///positive regulation of dendritic spine development+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901985///positive regulation of protein acetylation 52174 52174 'Tmem222' mRNA 1576 1702 1568 62.62 66.83 66.07 61.64 64.81 63.61 65.17333333 63.35333333 1778 1827 1776 1615.333333 1793.666667 0.08722392 0.140153161 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 52184 52184 'Odf2l' mRNA 424.15 447.69 370.71 7.56 8.37 7.56 5.04 4.55 6.22 7.83 5.27 294.42 256.59 336.4 414.1833333 295.8033333 9.42E-04 -0.495394096 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:1902017///regulation of cilium assembly+++GO:1902018///negative regulation of cilium assembly 52187 52187 'Rragd' mRNA 1148 1138 575 12.15 11.84 6.52 6.1 8.98 8.3 10.17 7.793333333 655 955 875 953.6666667 828.3333333 0.665933987 -0.195973493 04140///Autophagy - animal+++04150///mTOR signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071986///Ragulator complex+++GO:1990131///Gtr1-Gtr2 GTPase complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0046982///protein heterodimerization activity+++GO:0051020///GTPase binding GO:0009267///cellular response to starvation+++GO:0010506///regulation of autophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:1904263///positive regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 52202 52202 'Rbm34' mRNA 400.9 376.76 391.98 6.5 6.01 6.73 6.49 7.38 6.72 6.413333333 6.863333333 461.01 511.99 461.63 389.88 478.21 0.039399183 0.284418891 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0008150///biological_process 52206 52206 'Anapc4' mRNA 1180 1107 1185 24.51 22.63 26.11 25.75 26.05 25.38 24.41666667 25.72666667 1426 1409 1361 1157.333333 1398.666667 0.004222581 0.259697516 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0034399///nuclear periphery GO:0019903///protein phosphatase binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 52231 52231 'Ankzf1' mRNA 766.34 830.74 810.99 19.35 21.87 20.66 9.05 10.74 8.89 20.62666667 9.56 410.59 468.4 401.46 802.69 426.8166667 1.54E-15 -0.923295367 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0070301///cellular response to hydrogen peroxide 52245 52245 'Commd2' mRNA 458 489 469 8.5 8.94 9.24 11.33 11.32 11.9 8.893333333 11.51666667 702 685 714 472 700.3333333 3.26E-07 0.557317655 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 52250 52250 'Reep1' mRNA 160 178 126 2.28 2.49 1.9 2.95 2.53 2.77 2.223333333 2.75 239 200 217 154.6666667 218.6666667 0.013058072 0.491809838 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031849///olfactory receptor binding GO:0032386///regulation of intracellular transport+++GO:0051205///protein insertion into membrane+++GO:0071786///endoplasmic reticulum tubular network organization 52276 52276 'Cdca8' mRNA 15 21 31 0.54 0.74 1.18 14.76 13.55 13.02 0.82 13.77666667 472 423 403 22.33333333 432.6666667 1.85E-69 4.259491386 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0010369///chromocenter+++GO:0030496///midbody+++GO:0032133///chromosome passenger complex+++GO:0032991///protein-containing complex+++GO:0045171///intercellular bridge+++GO:0051233///spindle midzone" GO:0005515///protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0051276///chromosome organization+++GO:0051301///cell division 52323 52323 'Klhl7' mRNA 1130.27 1231.17 1135.4 16.97 18.02 18.1 12.29 12.9 12.54 17.69666667 12.57666667 931.92 946.88 907.65 1165.613333 928.8166667 1.47E-04 -0.339719439 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0016567///protein ubiquitination 52331 52331 'Stbd1' mRNA 68 69 64 1.95 1.95 1.95 4.94 6.96 7.87 1.95 6.59 198 272 305 67 258.3333333 2.00E-17 1.939452509 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0034045///phagophore assembly site membrane+++GO:0048471///perinuclear region of cytoplasm GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding+++GO:2001069///glycogen binding+++GO:2001070///starch binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process+++GO:0006914///autophagy+++GO:0046907///intracellular transport+++GO:0061723///glycophagy 52335 52335 'Atxn1l' mRNA 356 368 315 2.49 2.54 2.35 2.19 1.67 2.12 2.46 1.993333333 359 268 339 346.3333333 322 0.531168032 -0.116477963 04330///Notch signaling pathway+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0007612///learning+++GO:0007613///memory+++GO:0030198///extracellular matrix organization+++GO:0035176///social behavior+++GO:0048286///lung alveolus development+++GO:0048856///anatomical structure development+++GO:1902035///positive regulation of hematopoietic stem cell proliferation" 52348 52348 'Vps37a' mRNA 1081.07 1130.67 1029.43 9.02 9.28 9.09 7.75 7.81 8.15 9.13 7.903333333 1067.9 1049.43 1090.51 1080.39 1069.28 0.832474261 -0.025929427 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006612///protein targeting to membrane+++GO:0006623///protein targeting to vacuole+++GO:0015031///protein transport+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 52357 52357 'Wwc2' mRNA 742 763 696 6.3 6.31 6.4 4.96 4.47 5.15 6.336666667 4.86 661 582 672 733.6666667 638.3333333 0.057369521 -0.21220373 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019900///kinase binding+++GO:0060090///molecular adaptor activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016477///cell migration+++GO:0035330///regulation of hippo signaling+++GO:0035331///negative regulation of hippo signaling+++GO:0046621///negative regulation of organ growth" 52372 52372 'D6Ertd527e' mRNA 43.79 27.98 22.44 0.3 0.19 0.16 0.09 0.09 0.11 0.216666667 0.096666667 15.01 14.85 17.84 31.40333333 15.9 0.077228413 -1.00478117 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 52377 52377 'Rcn3' mRNA 2481 2371 2373 101.58 95.71 103.15 126.9 133.67 131.45 100.1466667 130.6733333 3558 3660 3567 2408.333333 3595 6.68E-18 0.566159588 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0043231///intracellular membrane-bounded organelle GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0009306///protein secretion+++GO:0010952///positive regulation of peptidase activity+++GO:0015031///protein transport+++GO:0032964///collagen biosynthetic process+++GO:0036503///ERAD pathway+++GO:0043129///surfactant homeostasis+++GO:0051896///regulation of protein kinase B signaling+++GO:0055091///phospholipid homeostasis+++GO:0060428///lung epithelium development 52389 52389 'Adgra1' mRNA 164 159 136 1.86 1.77 1.64 0.31 0.21 0.32 1.756666667 0.28 30 21 31 153 27.33333333 2.06E-18 -2.495007225 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse GO:0003674///molecular_function+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway 52392 52392 'Macir' mRNA 243 212 177 4.79 4.16 3.77 7.72 7.99 9.76 4.24 8.49 438 446 540 210.6666667 474.6666667 5.92E-14 1.164811251 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection GO:0003674///molecular_function GO:0006954///inflammatory response+++GO:0010764///negative regulation of fibroblast migration+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0050728///negative regulation of inflammatory response+++GO:0060271///cilium assembly+++GO:1900016///negative regulation of cytokine production involved in inflammatory response 52397 52397 'Zfp644' mRNA 996 872 798 9.12 7.92 7.73 6.65 5.71 5.86 8.256666667 6.073333333 806 702 709 888.6666667 739 0.01152824 -0.276676967 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding" GO:0006357///regulation of transcription by RNA polymerase II 52398 52398 'Septin11' mRNA 1956.24 1878.94 1817.91 20.76 20.07 21.11 24.5 26.2 24.44 20.64666667 25.04666667 2527.35 2466 2482.98 1884.363333 2492.11 5.37E-09 0.392068895 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031105///septin complex+++GO:0032153///cell division site+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099629///postsynaptic specialization of symmetric synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0034613///cellular protein localization+++GO:0050807///regulation of synapse organization+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis 52428 52428 'Rhpn2' mRNA 856 898 950 13.55 13.99 15.95 9.32 9.12 8.92 14.49666667 9.12 677.54 647.5 628 901.3333333 651.0133333 5.39E-06 -0.484764184 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0003094///glomerular filtration+++GO:0007165///signal transduction+++GO:0051497///negative regulation of stress fiber assembly 52430 52430 'Echdc2' mRNA 432 430 476 18.16 17.7 20.71 14.3 16.03 17.62 18.85666667 15.98333333 382 421 461 446 421.3333333 0.592186476 -0.095649994 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016829///lyase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation 52432 52432 'Ppp2r2d' mRNA 230 199 179 6.96 5.98 5.7 8.98 7.25 7.12 6.213333333 7.783333333 340 264 260 202.6666667 288 0.00610434 0.495445678 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019888///protein phosphatase regulator activity GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0010458///exit from mitosis+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0070262///peptidyl-serine dephosphorylation 52440 52440 'Tax1bp1' mRNA 4676 4687 4478 77.82 76.7 79 75.73 78.5 75.69 77.84 76.64 5238 5296 5066 4613.666667 5200 0.007299669 0.161209976 04137///Mitophagy - animal GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043066///negative regulation of apoptotic process 52443 52443 'Mrpl48' mRNA 1548 1626 1542 59.54 59 61.91 49.95 58.99 54.4 60.15 54.44666667 1209 1376 1257 1572 1280.666667 6.24E-04 -0.306254623 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 52463 52463 'Tet1' mRNA 1253 1253 1073 6.02 5.94 5.47 1.9 2.04 2.17 5.81 2.036666667 489 490 543 1193 507.3333333 9.57E-38 -1.242322927 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0070579///methylcytosine dioxygenase activity GO:0001826///inner cell mass cell differentiation+++GO:0006211///5-methylcytosine catabolic process+++GO:0006325///chromatin organization+++GO:0006493///protein O-linked glycosylation+++GO:0008284///positive regulation of cell proliferation+++GO:0019827///stem cell population maintenance+++GO:0031062///positive regulation of histone methylation+++GO:0035511///oxidative DNA demethylation+++GO:0044030///regulation of DNA methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048813///dendrite morphogenesis+++GO:0070989///oxidative demethylation+++GO:0080111///DNA demethylation+++GO:0090310///negative regulation of methylation-dependent chromatin silencing+++GO:2000653///regulation of genetic imprinting 52466 52466 'Slc46a1' mRNA 671 742 726 19.38 21.12 22.25 10.93 11.38 10.25 20.91666667 10.85333333 435 442 395 713 424 5.24E-11 -0.762646808 01523///Antifolate resistance+++04977///Vitamin digestion and absorption+++04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005542///folic acid binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0015232///heme transporter activity+++GO:0015350///methotrexate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015884///folic acid transport+++GO:0015886///heme transport+++GO:0051958///methotrexate transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1904447///folate import across plasma membrane 52468 52468 'Ctdsp2' mRNA 2257 2258 2098 28.39 28.35 28.15 29.7 27.65 30.88 28.29666667 29.41 2678 2440 2705 2204.333333 2607.666667 9.00E-04 0.231011334 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 52469 52469 'Coa3' mRNA 1078 1079 1088 106.25 105.57 113.81 115.85 134.9 121.23 108.5433333 123.9933333 1344 1523 1357 1081.666667 1408 9.66E-05 0.368837127 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0070131///positive regulation of mitochondrial translation 52477 52477 'Angel2' mRNA 989 982 922 16.4 16.14 16.31 13.32 13.35 12.7 16.28333333 13.12333333 921 906 853 964.3333333 893.3333333 0.235571043 -0.121504009 GO:0005737///cytoplasm+++GO:0015030///Cajal body GO:0000175///3'-5'-exoribonuclease activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0003824///catalytic activity "GO:0045930///negative regulation of mitotic cell cycle+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 52502 52502 'Carhsp1' mRNA 761 752 739 14.73 14.28 15.16 31.2 33.81 32.32 14.72333333 32.44333333 1855 1965 1863 750.6666667 1894.333333 1.57E-58 1.324217509 GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043186///P granule GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding GO:0043488///regulation of mRNA stability 52504 52504 'Cenpo' mRNA 360.46 339.1 308.17 7.48 6.85 6.94 5.29 5.07 4.79 7.09 5.05 272.57 254.62 243.71 335.91 256.9666667 0.00882458 -0.399520024 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0031511///Mis6-Sim4 complex" GO:0008150///biological_process+++GO:0034508///centromere complex assembly 52513 52513 'Ddx56' mRNA 1248 1219 1200 29.99 29.37 31.02 25.55 25.61 26.57 30.12666667 25.91 1122 1100 1137 1222.333333 1119.666667 0.131974798 -0.13849114 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0010976///positive regulation of neuron projection development+++GO:0042254///ribosome biogenesis 52521 52521 'Zfp622' mRNA 419 444 88 8.25 8.61 1.84 2.53 4.63 4.74 6.233333333 3.966666667 148 264 268 317 226.6666667 0.615571341 -0.46082015 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030687///preribosome, large subunit precursor" GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0033674///positive regulation of kinase activity+++GO:0042273///ribosomal large subunit biogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade 52530 52530 'Nhp2' mRNA 440 456 365 27.85 28.55 24.52 49.64 55.57 47.08 26.97333333 50.76333333 899 981 824 420.3333333 901.3333333 8.95E-22 1.093035644 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0015030///Cajal body+++GO:0031429///box H/ACA snoRNP complex+++GO:0090661///box H/ACA telomerase RNP complex GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0034511///U3 snoRNA binding+++GO:0034513///box H/ACA snoRNA binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0000469///cleavage involved in rRNA processing+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031118///rRNA pseudouridine synthesis+++GO:0031120///snRNA pseudouridine synthesis+++GO:0042254///ribosome biogenesis 52535 52535 'Mettl17' mRNA 448 456 436 16.13 16.18 16.65 12.53 13.48 12.17 16.32 12.72666667 400 420 376 446.6666667 398.6666667 0.220232931 -0.175258064 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0097177///mitochondrial ribosome binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0006412///translation+++GO:0032259///methylation+++GO:0042274///ribosomal small subunit biogenesis 52538 52538 'Acaa2' mRNA 1984 2089 2064 78.16 81.17 86.26 89.3 92.08 92.06 81.86333333 91.14666667 2604 2620 2597 2045.666667 2607 2.83E-06 0.33730056 "00062///Fatty acid elongation+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++01212///Fatty acid metabolism" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix "GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016787///hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity" GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0071456///cellular response to hypoxia+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process 52551 52551 'Sgta' mRNA 3839 3778 3731 104.42 101.22 107.61 87.5 90.56 87.14 104.4166667 88.4 3695 3740 3561 3782.666667 3665.333333 0.453226304 -0.057489642 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0072380///TRC complex+++GO:0098793///presynapse+++GO:0098850///extrinsic component of synaptic vesicle membrane GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043621///protein self-association+++GO:0046982///protein heterodimerization activity+++GO:0060090///molecular adaptor activity+++GO:1904288///BAT3 complex binding GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0061077///chaperone-mediated protein folding+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1903070///negative regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1903646///positive regulation of chaperone-mediated protein folding+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 52552 52552 'Parp8' mRNA 856 851 707 7.65 6.89 6.5 2.94 2.41 2.69 7.013333333 2.68 422 334 364 804.6666667 373.3333333 6.25E-22 -1.118003464 GO:0005622///intracellular+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity" GO:0006471///protein ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation 52563 52563 'Cdc23' mRNA 2435.93 2598.7 2579.15 31.46 33.11 35.38 20.63 20.78 19.24 33.31666667 20.21666667 1834.63 1806.17 1657.77 2537.926667 1766.19 3.35E-12 -0.536353118 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 52570 52570 'Ccdc69' mRNA 36 33 29 1.51 1.33 1.29 3.15 2.29 2.31 1.376666667 2.583333333 86 61 62 32.66666667 69.66666667 0.002847633 1.08017588 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0051233///spindle midzone GO:0008017///microtubule binding GO:0051255///spindle midzone assembly 52575 52575 'Trmt10c' mRNA 366 384 358 11.31 11.69 11.74 12.55 11.62 13.08 11.58 12.41666667 467 422 471 369.3333333 453.3333333 0.034610169 0.283845434 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0030678///mitochondrial ribonuclease P complex+++GO:0042645///mitochondrial nucleoid GO:0000049///tRNA binding+++GO:0008168///methyltransferase activity+++GO:0009019///tRNA (guanine-N1-)-methyltransferase activity+++GO:0016429///tRNA (adenine-N1-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0052905///tRNA (guanine(9)-N(1))-methyltransferase activity+++GO:0061953///mRNA (adenine-N1-)-methyltransferase activity GO:0000964///mitochondrial RNA 5'-end processing+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0070131///positive regulation of mitochondrial translation+++GO:0080009///mRNA methylation+++GO:0090646///mitochondrial tRNA processing+++GO:0097745///mitochondrial tRNA 5'-end processing+++GO:1990180///mitochondrial tRNA 3'-end processing 52585 52585 'Dhrs1' mRNA 1436 1560 1486 57.76 61.88 63.39 71.6 80.1 69.92 61.01 73.87333333 2043 2230 1932 1494 2068.333333 7.30E-08 0.457929525 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity GO:0008150///biological_process 52588 52588 'Tspan14' mRNA 3361 3521 3438 74.16 76.39 80.45 73.49 69.17 67.37 77 70.01 3846 3540 3402 3440 3596 0.550936895 0.050679554 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097197///tetraspanin-enriched microdomain GO:0019899///enzyme binding GO:0045747///positive regulation of Notch signaling pathway+++GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane 52589 52589 'Ncald' mRNA 1138 983 1104 17.87 15.24 18.4 13.66 14.58 14.88 17.17 14.37333333 991 1042 1058 1075 1030.333333 0.560541708 -0.074529339 04740///Olfactory transduction GO:0005829///cytosol GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0015631///tubulin binding+++GO:0030276///clathrin binding+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding GO:0003073///regulation of systemic arterial blood pressure+++GO:0019722///calcium-mediated signaling 52592 52592 'Brms1l' mRNA 605 567 566 13.1 12.09 13 14.63 14.32 12.54 12.73 13.83 777 743 645 579.3333333 721.6666667 0.009373249 0.304481347 GO:0005634///nucleus+++GO:0070822///Sin3-type complex GO:0042826///histone deacetylase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation+++GO:0040008///regulation of growth 52609 52609 'Cbx7' mRNA 1149 1072 638 20.73 19.12 12.48 5.37 6.21 6.19 17.44333333 5.923333333 334 378 375 953 362.3333333 1.76E-18 -1.394142375 GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048733///sebaceous gland development" 52614 52614 'Adgre4' mRNA 6 7 6 0.09 0.11 0.1 0.22 0.44 0.08 0.1 0.246666667 16 32 6 6.333333333 18 0.081298866 1.502357061 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway 52615 52615 'Suz12' mRNA 305 318 318 3.77 3.88 4.2 3.86 4.33 3.98 3.95 4.056666667 357 393 359 313.6666667 369.6666667 0.150662781 0.225159177 GO:0001739///sex chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0032993///protein-DNA complex+++GO:0035098///ESC/E(Z) complex+++GO:1990904///ribonucleoprotein complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0031490///chromatin DNA binding+++GO:0035064///methylated histone binding+++GO:0042054///histone methyltransferase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0008284///positive regulation of cell proliferation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0010467///gene expression+++GO:0016571///histone methylation+++GO:0016574///histone ubiquitination+++GO:0021510///spinal cord development+++GO:0032526///response to retinoic acid+++GO:0032682///negative regulation of chemokine production+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0045596///negative regulation of cell differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0098532///histone H3-K27 trimethylation 52626 52626 'Cdkn2aipnl' mRNA 922 976 988 28.39 29.61 32.27 31.31 29.66 29.62 30.09 30.19666667 1169 1081 1070 962 1106.666667 0.059044995 0.188255024 GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function 52633 52633 'Nit2' mRNA 359 330 336 16.92 15.36 16.8 21.23 22.23 20.97 16.36 21.47666667 517 528 494 341.6666667 513 6.13E-06 0.574554639 "00250///Alanine, aspartate and glutamate metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0016787///hydrolase activity+++GO:0050152///omega-amidase activity+++GO:0106008///2-oxoglutaramate amidase activity GO:0006107///oxaloacetate metabolic process+++GO:0006528///asparagine metabolic process+++GO:0006541///glutamine metabolic process+++GO:0006807///nitrogen compound metabolic process 52635 52635 'Esyt2' mRNA 618.03 695.18 583.74 4.3 4.16 3.79 5.71 5.79 5.58 4.083333333 5.693333333 879.37 863.26 829.06 632.3166667 857.23 2.15E-05 0.429659746 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0044232///organelle membrane contact site GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0061817///endoplasmic reticulum-plasma membrane tethering 52637 52637 'Cisd1' mRNA 1758 1757 1753 117.52 116.19 124.35 97.98 101.14 101.16 119.3533333 100.0933333 1680 1690 1676 1756 1682 0.409847043 -0.0744174 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032473///cytoplasmic side of mitochondrial outer membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0005506///iron ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0010506///regulation of autophagy+++GO:0043457///regulation of cellular respiration 52639 52639 'Wipi1' mRNA 730 736 639 23.13 22.98 21.48 23.21 25.39 25.47 22.53 24.69 842 899 894 701.6666667 878.3333333 0.001948591 0.315203956 04136///Autophagy - other+++04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis GO:0000407///phagophore assembly site+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0034045///phagophore assembly site membrane "GO:0005102///signaling receptor binding+++GO:0008289///lipid binding+++GO:0030331///estrogen receptor binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0050681///androgen receptor binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0034497///protein localization to phagophore assembly site+++GO:0044804///autophagy of nucleus+++GO:0048203///vesicle targeting, trans-Golgi to endosome" 52653 52653 'Nudcd2' mRNA 399 393 379 14.7 14.19 14.66 24.98 24.56 26.38 14.51666667 25.30666667 778 749 800 390.3333333 775.6666667 6.29E-20 0.97924097 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle" GO:0051082///unfolded protein binding GO:0006457///protein folding 52662 52662 'Ldlrad4' mRNA 576.46 578.73 492.05 4.3 3.83 4.32 2.12 2.44 2.32 4.15 2.293333333 475.83 416.38 416.11 549.08 436.1066667 0.005494154 -0.342828689 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0070412///R-SMAD binding GO:0009968///negative regulation of signal transduction+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010991///negative regulation of SMAD protein complex assembly+++GO:0030336///negative regulation of cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation 52665 52665 'Echdc1' mRNA 971.18 926.08 861.92 12.54 11.16 12.02 9.33 10.3 7.43 11.90666667 9.02 804.58 821.53 658.8 919.7266667 761.6366667 0.0122469 -0.283281528 00640///Propanoate metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity GO:0006635///fatty acid beta-oxidation 52666 52666 'Arhgef25' mRNA 485 511 456 11.98 12.39 11.75 10.67 11.16 9.91 12.04 10.58 494 513 447 484 484.6666667 0.962710753 -0.008203447 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030016///myofibril+++GO:0030017///sarcomere GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0007411///axon guidance+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity 52668 52668 'Ifi27' mRNA 10048 10392 9417 646.93 662.48 643.48 573.54 597.56 575.72 650.9633333 582.2733333 10303 10499 10017 9952.333333 10273 0.593786461 0.035463281 GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005521///lamin binding+++GO:0042802///identical protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044827///modulation by host of viral genome replication+++GO:0045087///innate immune response+++GO:0046825///regulation of protein export from nucleus+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0070936///protein K48-linked ubiquitination+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway 52670 52670 'Cpsf4l' mRNA 227 257 266 10.88 12.11 13.54 9.24 13.01 12.45 12.17666667 11.56666667 223 307 281 250 270.3333333 0.672062509 0.101453174 GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0046872///metal ion binding GO:0098789///pre-mRNA cleavage required for polyadenylation 52679 52679 'E2f7' mRNA 7 5 4 0.07 0.05 0.04 0.65 0.68 0.67 0.053333333 0.666666667 77 79 78 5.333333333 78 1.48E-14 3.861926493 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016607///nuclear speck+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001217///bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001890///placenta development+++GO:0002040///sprouting angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0032466///negative regulation of cytokinesis+++GO:0032877///positive regulation of DNA endoreduplication+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060707///trophoblast giant cell differentiation+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0070365///hepatocyte differentiation+++GO:0071930///negative regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 52683 52683 'Ncaph2' mRNA 2420.32 2512.72 2324.94 39.66 40.55 40.52 40.14 37.6 39.91 40.24333333 39.21666667 2816.99 2576.81 2712.65 2419.326667 2702.15 0.031018707 0.147768631 GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0030054///cell junction+++GO:0045171///intercellular bridge GO:0003682///chromatin binding GO:0007076///mitotic chromosome condensation+++GO:0007143///female meiotic nuclear division+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0033077///T cell differentiation in thymus+++GO:0051306///mitotic sister chromatid separation+++GO:0051309///female meiosis chromosome separation 52685 52685 'Cd300lg' mRNA 9 7 6 0.21 0.16 0.15 0.3 0.35 0.3 0.173333333 0.316666667 13 17 15 7.333333333 15 0.207857747 1.026712165 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0032585///multivesicular body membrane GO:0001791///IgM binding+++GO:0004888///transmembrane signaling receptor activity GO:0002376///immune system process+++GO:0002414///immunoglobulin transcytosis in epithelial cells 52686 52686 'Mettl2' mRNA 330.84 281.12 344.95 7.12 5.9 7.85 6.36 6.31 7.12 6.956666667 6.596666667 336.15 329.02 370.45 318.97 345.2066667 0.612251631 0.100731563 GO:0005575///cellular_component GO:0008168///methyltransferase activity+++GO:0016427///tRNA (cytosine) methyltransferase activity+++GO:0016740///transferase activity+++GO:0052735///tRNA (cytosine-3-)-methyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 52690 52690 'Setd3' mRNA 1694 1667 1467 36.8 36.2 34.01 27.3 26.01 27.62 35.67 26.97666667 1438 1328 1421 1609.333333 1395.666667 0.007070668 -0.215519669 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018064///protein-histidine N-methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046975///histone methyltransferase activity (H3-K36 specific)+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0010452///histone H3-K36 methylation+++GO:0018021///peptidyl-histidine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0030047///actin modification+++GO:0032259///methylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051568///histone H3-K4 methylation+++GO:0070472///regulation of uterine smooth muscle contraction" 52696 52696 'Zwint' mRNA 4137 4396 4128 128.49 134.21 136.02 80.21 82.24 85.53 132.9066667 82.66 2989 2983 3085 4220.333333 3019 8.19E-16 -0.4947454 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle" GO:0005515///protein binding+++GO:0047485///protein N-terminus binding GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0051301///cell division+++GO:0051649///establishment of localization in cell 52700 52700 'Txndc17' mRNA 1349 1346 1384 55.44 54.57 60.34 85.99 87.84 86 56.78333333 86.61 2403 2395 2325 1359.666667 2374.333333 2.96E-26 0.791256906 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004601///peroxidase activity+++GO:0047134///protein-disulfide reductase activity GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0098869///cellular oxidant detoxification 52705 52705 'Krr1' mRNA 682.94 701.47 653.93 7.31 7.39 7.43 6.76 7.26 7.09 7.376666667 7.036666667 727.19 762.8 738.7 679.4466667 742.8966667 0.308903382 0.118751362 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032040///small-subunit processome+++GO:0045171///intercellular bridge GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 52708 52708 'Zfp410' mRNA 965 993 1064 21.51 21.92 25.18 20.24 19.6 21.7 22.87 20.51333333 1025 987 1076 1007.333333 1029.333333 0.896734047 0.016742623 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 52710 52710 'Slc52a2' mRNA 736.1 738.15 696 4.52 4.45 4.53 4.09 3.66 3.94 4.5 3.896666667 767.45 672.15 715.79 723.4166667 718.4633333 0.863090843 -0.022816468 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0032217///riboflavin transmembrane transporter activity GO:0032218///riboflavin transport 52712 52712 'Zkscan6' mRNA 440 455 437 11.17 12.01 11.87 10.35 8.3 8.64 11.68333333 9.096666667 440 358 372 444 390 0.168037803 -0.200584835 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 52713 52713 'Ccdc59' mRNA 395 398 375 23.02 22.92 23.19 21.29 21.52 20.87 23.04333333 21.22666667 419 413 397 389.3333333 409.6666667 0.718059253 0.062178644 GO:0005634///nucleus 52715 52715 'Ccdc43' mRNA 680.58 663.17 669 12.53 11.87 12.59 13.71 15.48 14.21 12.33 14.46666667 800.52 842.1 789.9 670.9166667 810.84 0.014735956 0.261012476 GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 52717 52717 'Anapc16' mRNA 1038 1041 1169 32.08 31.74 38.32 32.01 33.06 30.56 34.04666667 31.87666667 1195 1201 1100 1082.666667 1165.333333 0.462724064 0.090781238 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0051301///cell division 52793 52793 'Fam3b' mRNA 0 0 1 0 0 0.07 0.06 0.06 0.12 0.023333333 0.08 1 1 2 0.333333333 1.333333333 0.577538 1.885860293 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005641///nuclear envelope lumen GO:0005125///cytokine activity GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0030073///insulin secretion+++GO:0042593///glucose homeostasis 52808 52808 'Tspyl2' mRNA 1161 1219 967 23.25 24.03 20.54 15.74 14.42 14.51 22.60666667 14.89 904 809 807 1115.666667 840 1.39E-05 -0.418135038 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0030308///negative regulation of cell growth+++GO:0045859///regulation of protein kinase activity 52815 52815 'Ldhd' mRNA 472.26 405.27 395.06 7.08 6.11 6.62 12.9 12.63 12.96 6.603333333 12.83 845.27 793.72 825.82 424.1966667 821.6033333 4.82E-18 0.942283407 00620///Pyruvate metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane GO:0003824///catalytic activity+++GO:0004458///D-lactate dehydrogenase (cytochrome) activity+++GO:0005515///protein binding+++GO:0008720///D-lactate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding GO:0006754///ATP biosynthetic process+++GO:1903457///lactate catabolic process 52822 52822 'Rufy3' mRNA 781.01 880.61 733.71 9.87 11 9.9 3.97 4.7 4.69 10.25666667 4.453333333 379.07 394.51 410.52 798.4433333 394.7 1.56E-20 -1.025848474 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0045773///positive regulation of axon extension+++GO:0050770///regulation of axonogenesis+++GO:0050771///negative regulation of axonogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0090316///positive regulation of intracellular protein transport+++GO:2000114///regulation of establishment of cell polarity 52829 52829 'Lurap1l' mRNA 751 829 767 25.66 27.93 27.81 10.44 12.22 10.14 27.13333333 10.93333333 351 401 330 782.3333333 360.6666667 2.32E-21 -1.127788628 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling 52830 52830 'Pnrc2' mRNA 1788 1909 1947 53.1 55.73 61.5 57.77 56.85 55.74 56.77666667 56.78666667 2237 2153 2095 1881.333333 2161.666667 0.025971791 0.186452294 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 52837 52837 'Tmx4' mRNA 1259.01 1296 1292 13.05 13.21 14.21 10.39 9.62 9.67 13.49 9.893333333 1154 1044 1039.95 1282.336667 1079.316667 0.003486345 -0.262610235 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 52838 52838 'Dnlz' mRNA 1205.54 1188 1137 23.03 22.25 23.01 17.78 19.73 18.27 22.76333333 18.59333333 1074 1165 1067 1176.846667 1102 0.303726205 -0.105254339 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0030150///protein import into mitochondrial matrix+++GO:0050821///protein stabilization 52840 52840 'Dbndd2' mRNA 797 725 535 11.59 10.39 8.28 10.23 11.5 11.43 10.08666667 11.05333333 803.49 880.69 871 685.6666667 851.7266667 0.018240118 0.308099423 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006469///negative regulation of protein kinase activity 52846 52846 'Cnot11' mRNA 113 112 65 1.89 1.84 1.15 1.74 0.83 1.45 1.626666667 1.34 120 56 97 96.66666667 91 0.83749634 -0.094081331 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex GO:0003674///molecular_function GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA 52850 52850 'Sgsm1' mRNA 815 909.06 860.37 8.9 9.63 10.04 1.02 1.49 1.54 9.523333333 1.35 98.12 121 151.6 861.4766667 123.5733333 3.48E-80 -2.814659609 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 52855 52855 'Lair1' mRNA 191 201 188 3.01 3.04 3.03 11.73 12.43 12.65 3.026666667 12.27 863 888 899 193.3333333 883.3333333 1.12E-76 2.181184881 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 52856 52856 'Mtg2' mRNA 767 795 769 21.79 22.01 23.83 15.19 15.09 16.23 22.54333333 15.50333333 598 590 606 777 598 1.61E-04 -0.389728244 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005761///mitochondrial ribosome GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0042254///ribosome biogenesis+++GO:0044065///regulation of respiratory system process+++GO:0070129///regulation of mitochondrial translation 52857 52857 'Gramd1a' mRNA 1582 1510 652 31.15 29.25 13.56 14.98 22.15 20.91 24.65333333 19.34666667 882 1268 1188 1248 1112.666667 0.785536103 -0.155134491 GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044232///organelle membrane contact site GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006869///lipid transport+++GO:0006914///autophagy+++GO:0015918///sterol transport+++GO:0071397///cellular response to cholesterol+++GO:0120009///intermembrane lipid transfer 52858 52858 'Cdipt' mRNA 3101 3289 3157 101.35 105.95 109.47 103.88 107.57 103.63 105.59 105.0266667 3653 3693 3527 3182.333333 3624.333333 0.009916278 0.175648853 00562///Inositol phosphate metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0019992///diacylglycerol binding+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0043178///alcohol binding" GO:0006629///lipid metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0046341///CDP-diacylglycerol metabolic process 52864 52864 'Slx4' mRNA 346 308 374 3.09 2.69 3.74 2.67 2.49 2.77 3.173333333 2.643333333 351 312 340 342.6666667 334.3333333 0.806988594 -0.052061889 03460///Fanconi anemia pathway "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0033557///Slx1-Slx4 complex+++GO:0048476///Holliday junction resolvase complex+++GO:0070522///ERCC4-ERCC1 complex" GO:0003677///DNA binding+++GO:0008047///enzyme activator activity+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0017108///5'-flap endonuclease activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0048257///3'-flap endonuclease activity GO:0000706///meiotic DNA double-strand break processing+++GO:0000712///resolution of meiotic recombination intermediates+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010792///DNA double-strand break processing involved in repair via single-strand annealing+++GO:0036297///interstrand cross-link repair+++GO:0050790///regulation of catalytic activity+++GO:0061820///telomeric D-loop disassembly+++GO:0072429///response to intra-S DNA damage checkpoint signaling+++GO:0090656///t-circle formation+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:1904431///positive regulation of t-circle formation 52874 52874 'Pum3' mRNA 622 645 686 9.51 9.64 11.09 11.38 11.27 11.77 10.08 11.47333333 862 832 861 651 851.6666667 5.31E-04 0.373441247 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006417///regulation of translation+++GO:0010835///regulation of protein ADP-ribosylation 52882 52882 'Rgs7bp' mRNA 104.94 104 96 0.94 0.91 0.89 1.09 0.98 0.94 0.913333333 1.003333333 142.02 124 116.02 101.6466667 127.3466667 0.219127101 0.31754871 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0044327///dendritic spine head+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099026///anchored component of presynaptic membrane+++GO:0099031///anchored component of postsynaptic density membrane GO:0005515///protein binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0060078///regulation of postsynaptic membrane potential 52892 52892 'Sco1' mRNA 334.43 326.61 304.08 4.19 4.03 4.05 3.59 3.12 3.52 4.09 3.41 329.19 279.88 312.53 321.7066667 307.2 0.675676317 -0.079241853 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030016///myofibril+++GO:0031305///integral component of mitochondrial inner membrane GO:0003674///molecular_function+++GO:0005507///copper ion binding+++GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding GO:0006878///cellular copper ion homeostasis+++GO:0008535///respiratory chain complex IV assembly+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0019371///cyclooxygenase pathway+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0072659///protein localization to plasma membrane+++GO:1900077///negative regulation of cellular response to insulin stimulus+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1904959///regulation of cytochrome-c oxidase activity 52897 52897 'Rbfox3' mRNA 242 221 168 4.15 3.57 2.88 0.29 0.56 0.45 3.533333333 0.433333333 24 38 29 210.3333333 30.33333333 1.67E-25 -2.797260425 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing" 52898 52898 'Rnasek' mRNA 4276 3808 3711 516.69 457.87 475.97 585.56 639.55 619.86 483.51 614.99 5531 5873 5644 3931.666667 5682.666667 8.96E-15 0.521179655 04212///Longevity regulating pathway - worm GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity "GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 52906 52906 'Ahi1' mRNA 1263 1249 1155 13.95 13.56 13.52 5.32 4.95 5.7 13.67666667 5.323333333 555 505 576 1222.333333 545.3333333 3.47E-37 -1.175529309 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005929///cilium+++GO:0030054///cell junction+++GO:0036038///MKS complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097730///non-motile cilium GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001738///morphogenesis of a polarized epithelium+++GO:0001947///heart looping+++GO:0002092///positive regulation of receptor internalization+++GO:0006903///vesicle targeting+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0010628///positive regulation of gene expression+++GO:0010842///retina layer formation+++GO:0010976///positive regulation of neuron projection development+++GO:0016192///vesicle-mediated transport+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0030862///positive regulation of polarized epithelial cell differentiation+++GO:0030902///hindbrain development+++GO:0033365///protein localization to organelle+++GO:0034613///cellular protein localization+++GO:0035844///cloaca development+++GO:0035845///photoreceptor cell outer segment organization+++GO:0039008///pronephric nephron tubule morphogenesis+++GO:0039023///pronephric duct morphogenesis+++GO:0042462///eye photoreceptor cell development+++GO:0043066///negative regulation of apoptotic process+++GO:0045927///positive regulation of growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046325///negative regulation of glucose import+++GO:0046548///retinal rod cell development+++GO:0046549///retinal cone cell development+++GO:0050708///regulation of protein secretion+++GO:0050795///regulation of behavior+++GO:0060041///retina development in camera-type eye+++GO:0060271///cilium assembly+++GO:0065001///specification of axis polarity+++GO:0070121///Kupffer's vesicle development+++GO:0070986///left/right axis specification+++GO:0071599///otic vesicle development+++GO:1905515///non-motile cilium assembly 52915 52915 'Zmiz2' mRNA 1044 1024 883 13.09 12.79 11.94 10.79 10.26 10.78 12.60666667 10.61 1021 923 980 983.6666667 974.6666667 0.863090843 -0.02307449 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0043596///nuclear replication fork GO:0008270///zinc ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046872///metal ion binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048096///chromatin-mediated maintenance of transcription" 53310 53310 'Dlg3' mRNA 183 157 160 2.64 2.24 2.53 1.88 1.7 2.14 2.47 1.906666667 154 135 163 166.6666667 150.6666667 0.524602445 -0.157771537 04390///Hippo signaling pathway+++04530///Tight junction+++05165///Human papillomavirus infection "GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0014069///postsynaptic density+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0032281///AMPA glutamate receptor complex+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019900///kinase binding+++GO:0019902///phosphatase binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0098919///structural constituent of postsynaptic density GO:0001736///establishment of planar polarity+++GO:0009790///embryo development+++GO:0010923///negative regulation of phosphatase activity+++GO:0043113///receptor clustering+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0097120///receptor localization to synapse+++GO:0098609///cell-cell adhesion+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0099562///maintenance of postsynaptic density structure 53311 53311 'Mybph' mRNA 6.11 3.12 4.06 0.19 0.1 0.13 0.2 0 0.15 0.14 0.116666667 7.21 0 5.21 4.43 4.14 0.936012214 -0.140329226 GO:0032982///myosin filament GO:0007155///cell adhesion 53312 53312 'Nub1' mRNA 2231 2296 2178 37.26 37.68 38.55 24.16 27.63 26.29 37.83 26.02666667 1667 1861 1757 2235 1761.666667 6.46E-06 -0.353839696 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process 53313 53313 'Atp2a3' mRNA 369 358 359 4.36 4.15 4.5 3.51 2.65 2.84 4.336666667 3 344 253 269 362 288.6666667 0.035921307 -0.341470496 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04919///Thyroid hormone signaling pathway+++04972///Pancreatic secretion+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy+++05415///Diabetic cardiomyopathy GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031090///organelle membrane+++GO:0033017///sarcoplasmic reticulum membrane "GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0016887///ATPase activity+++GO:0030899///calcium-dependent ATPase activity+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070588///calcium ion transmembrane transport+++GO:1900121///negative regulation of receptor binding+++GO:1903515///calcium ion transport from cytosol to endoplasmic reticulum 53314 53314 'Batf' mRNA 49 42 37 3.56 3.02 2.85 17.18 17.57 14.24 3.143333333 16.33 271 270 217 42.66666667 252.6666667 1.14E-28 2.55636691 05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001819///positive regulation of cytokine production+++GO:0002320///lymphoid progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030154///cell differentiation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0042832///defense response to protozoan+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045064///T-helper 2 cell differentiation+++GO:0045190///isotype switching+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060218///hematopoietic stem cell differentiation+++GO:0072539///T-helper 17 cell differentiation+++GO:0072540///T-helper 17 cell lineage commitment" 53315 53315 'Sult1d1' mRNA 0 0 1 0 0 0.02 0.04 0.1 0.02 0.006666667 0.053333333 2 5 1 0.333333333 2.666666667 0.252710414 2.892032444 GO:0005737///cytoplasm GO:0004062///aryl sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0000103///sulfate assimilation+++GO:0006584///catecholamine metabolic process+++GO:0006629///lipid metabolic process+++GO:0051923///sulfation 53317 53317 'Plrg1' mRNA 938 1023 867 30.59 32.88 29.99 29.25 28.02 31.93 31.15333333 29.73333333 1031 964 1089 942.6666667 1028 0.279928858 0.115261668 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005662///DNA replication factor A complex+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0034504///protein localization to nucleus+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle" 53318 53318 'Pdlim3' mRNA 17 19 10 0.59 0.65 0.37 0.27 0.5 0.44 0.536666667 0.403333333 9 16 14 15.33333333 13 0.796598969 -0.235005546 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008307///structural constituent of muscle+++GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding GO:0007015///actin filament organization+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0030036///actin cytoskeleton organization+++GO:0061061///muscle structure development 53319 53319 'Nxf1' mRNA 5312 5390 5483 86.1 86.07 93.72 49.56 49.33 47.77 88.63 48.88666667 3207 3113 2977 5395 3099 1.15E-36 -0.813389009 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0042405///nuclear inclusion body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0015031///protein transport+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 53320 53320 'Folh1' mRNA 2 4 4 0.04 0.07 0.08 0.13 0.04 0.14 0.063333333 0.103333333 8 3 8 3.333333333 6.333333333 0.509513445 0.904539386 "00250///Alanine, aspartate and glutamate metabolism+++04977///Vitamin digestion and absorption" GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:1904492///Ac-Asp-Glu binding+++GO:1904493///tetrahydrofolyl-poly(glutamate) polymer binding GO:0006508///proteolysis+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008152///metabolic process+++GO:0043065///positive regulation of apoptotic process 53321 53321 'Cntnap1' mRNA 254 250 159 2.53 2.44 1.7 2.12 1.73 2.16 2.223333333 2.003333333 253 195 245 221 231 0.836251542 0.058935482 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005918///septate junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0033010///paranodal junction+++GO:0033270///paranode region of axon+++GO:0043209///myelin sheath+++GO:0048787///presynaptic active zone membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding "GO:0002175///protein localization to paranode region of axon+++GO:0007005///mitochondrion organization+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0007409///axonogenesis+++GO:0019227///neuronal action potential propagation+++GO:0022010///central nervous system myelination+++GO:0022011///myelination in peripheral nervous system+++GO:0030913///paranodal junction assembly+++GO:0031175///neuron projection development+++GO:0042552///myelination+++GO:0048812///neuron projection morphogenesis+++GO:0050884///neuromuscular process controlling posture+++GO:0050885///neuromuscular process controlling balance+++GO:0050905///neuromuscular process+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0097106///postsynaptic density organization+++GO:0098529///neuromuscular junction development, skeletal muscle fiber+++GO:1990227///paranodal junction maintenance" 53322 53322 'Nucb2' mRNA 787 718 773 27.12 24.37 28.26 36.43 37.39 39.57 26.58333333 37.79666667 1206 1217 1272 759.3333333 1231.666667 4.90E-13 0.684887246 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0016020///membrane+++GO:0043204///perikaryon GO:0001965///G-protein alpha-subunit binding+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0006874///cellular calcium ion homeostasis+++GO:0007264///small GTPase mediated signal transduction+++GO:0032099///negative regulation of appetite+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045599///negative regulation of fat cell differentiation+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0070093///negative regulation of glucagon secretion+++GO:1901142///insulin metabolic process+++GO:2000845///positive regulation of testosterone secretion 53323 53323 'Ube2k' mRNA 928 919 922 10.17 9.91 10.72 13.36 13.69 13.3 10.26666667 13.45 1403 1405 1353 923 1387 9.27E-12 0.575259115 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032433///filopodium tip GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035458///cellular response to interferon-beta+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070936///protein K48-linked ubiquitination+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway 53324 53324 'Nptx2' mRNA 9 16 8 0.2 0.34 0.19 0.23 0.16 0.08 0.243333333 0.156666667 12 8 4 11 8 0.662170226 -0.466295129 GO:0005576///extracellular region+++GO:0098892///extrinsic component of postsynaptic specialization membrane+++GO:0098978///glutamatergic synapse GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding GO:0008306///associative learning+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 53325 53325 'Banp' mRNA 682 767 696 16.43 18.91 19.48 15.84 14.9 15.23 18.27333333 15.32333333 757 656 649 715 687.3333333 0.613476508 -0.069418382 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0034504///protein localization to nucleus+++GO:0042177///negative regulation of protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated" 53328 53328 'Pgrmc1' mRNA 8999 9556 9489 276.09 288.9 308.84 288.92 288.85 279.1 291.2766667 285.6233333 10825 10564 10120 9348 10503 0.015895624 0.154703721 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044297///cell body+++GO:0045202///synapse GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0020037///heme binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006783///heme biosynthetic process+++GO:0007613///memory+++GO:0008306///associative learning+++GO:0099563///modification of synaptic structure+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905809///negative regulation of synapse organization 53330 53330 'Vamp4' mRNA 1373 1507 1396 14.81 15.55 16 12.72 12.32 11.46 15.45333333 12.16666667 1390 1323.77 1245 1425.333333 1319.59 0.183430061 -0.123499735 04130///SNARE interactions in vesicular transport GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0008021///synaptic vesicle+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0045335///phagocytic vesicle+++GO:0099067///integral component of presynaptic endosome membrane GO:0000226///microtubule cytoskeleton organization+++GO:0016189///synaptic vesicle to endosome fusion+++GO:0016192///vesicle-mediated transport+++GO:0035493///SNARE complex assembly+++GO:0042996///regulation of Golgi to plasma membrane protein transport+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0071346///cellular response to interferon-gamma+++GO:0090161///Golgi ribbon formation+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1901998///toxin transport 53331 53331 'Stx7' mRNA 3120 3202 3118 78.77 79.72 83.59 83.14 83.3 79.75 80.69333333 82.06333333 3772 3686 3503 3146.666667 3653.666667 0.002113076 0.203116847 04130///SNARE interactions in vesicular transport+++04145///Phagosome GO:0001772///immunological synapse+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0042582///azurophil granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0070820///tertiary granule GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019869///chloride channel inhibitor activity+++GO:0019905///syntaxin binding+++GO:0044877///protein-containing complex binding GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0008333///endosome to lysosome transport+++GO:0016192///vesicle-mediated transport+++GO:0048278///vesicle docking+++GO:0051640///organelle localization+++GO:0061025///membrane fusion+++GO:0070925///organelle assembly+++GO:1902685///positive regulation of receptor localization to synapse+++GO:1903076///regulation of protein localization to plasma membrane 53332 53332 'Mtmr1' mRNA 249 281 233 2.99 3.34 3.05 2.76 2.36 2.66 3.126666667 2.593333333 261 217 241 254.3333333 239.6666667 0.648109849 -0.096369341 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity+++GO:0052866///phosphatidylinositol phosphate phosphatase activity" GO:0006629///lipid metabolic process+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0060304///regulation of phosphatidylinositol dephosphorylation 53333 53333 'Tomm40' mRNA 1423 1501 1319 53.04 55.26 52.23 62.79 61.94 62.81 53.51 62.51333333 1935 1861 1871 1414.333333 1889 1.53E-08 0.407207746 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0046930///pore complex GO:0005261///cation channel activity+++GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0070678///preprotein binding GO:0006626///protein targeting to mitochondrion+++GO:0006811///ion transport+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0034220///ion transmembrane transport+++GO:0043065///positive regulation of apoptotic process+++GO:0051204///protein insertion into mitochondrial membrane+++GO:0055085///transmembrane transport+++GO:0098655///cation transmembrane transport 53334 53334 'Gosr1' mRNA 1137 1158 1235 14.26 14.29 16.44 14.14 13.66 13.26 14.99666667 13.68666667 1297 1224 1178 1176.666667 1233 0.665933987 0.052740456 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex GO:0005484///SNAP receptor activity "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048209///regulation of vesicle targeting, to, from or within Golgi" 53356 53356 'Eif3g' mRNA 1999 1924 1938 117.82 112.09 121.2 124.21 131.47 125.84 117.0366667 127.1733333 2417 2494 2367 1953.666667 2426 4.54E-05 0.300360766 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0048471///perinuclear region of cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0075525///viral translational termination-reinitiation 53357 53357 'Pla2g6' mRNA 717 700 725 11.81 11.5 12.76 7.12 6.86 5.73 12.02333333 6.57 500 461 387 714 449.3333333 2.48E-08 -0.68230052 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04666///Fc gamma R-mediated phagocytosis+++04750///Inflammatory mediator regulation of TRP channels GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031143///pseudopodium+++GO:0034451///centriolar satellite+++GO:0042995///cell projection "GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0005516///calmodulin binding+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0017171///serine hydrolase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0043008///ATP-dependent protein binding+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0102991///myristoyl-CoA hydrolase activity" "GO:0001934///positive regulation of protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006935///chemotaxis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007613///memory+++GO:0014832///urinary bladder smooth muscle contraction+++GO:0016042///lipid catabolic process+++GO:0019731///antibacterial humoral response+++GO:0032049///cardiolipin biosynthetic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0042311///vasodilation+++GO:0045921///positive regulation of exocytosis+++GO:0046338///phosphatidylethanolamine catabolic process+++GO:0046469///platelet activating factor metabolic process+++GO:0046473///phosphatidic acid metabolic process+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0060135///maternal process involved in female pregnancy+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:1901339///regulation of store-operated calcium channel activity+++GO:2000304///positive regulation of ceramide biosynthetic process" 53374 53374 'Chst3' mRNA 368.44 309.06 300.79 1.09 0.98 0.94 0.8 0.92 0.78 1.003333333 0.833333333 308.41 318.63 271.29 326.0966667 299.4433333 0.471828131 -0.133525491 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0008459///chondroitin 6-sulfotransferase activity+++GO:0016740///transferase activity+++GO:0050698///proteoglycan sulfotransferase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0043029///T cell homeostasis+++GO:0051272///positive regulation of cellular component movement 53375 53375 'Mtx2' mRNA 788 852 812 38.13 40.7 41.68 49.78 49.78 49.3 40.17 49.62 1181 1152 1131 817.3333333 1154.666667 5.58E-08 0.486389368 GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0007005///mitochondrion organization+++GO:0015031///protein transport 53376 53376 'Usp2' mRNA 3004 3206 2715 44.48 47.33 42.84 24.89 23.44 23.57 44.88333333 23.96666667 1889 1730 1731 2975 1783.333333 5.45E-29 -0.74826624 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0030332///cyclin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0007517///muscle organ development+++GO:0016579///protein deubiquitination+++GO:0032922///circadian regulation of gene expression+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0045475///locomotor rhythm+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0048511///rhythmic process+++GO:0048512///circadian behavior+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0050821///protein stabilization+++GO:0051926///negative regulation of calcium ion transport 53378 53378 'Sdcbp' mRNA 6114 6434 6570 144.02 149.22 164.07 377.56 365.04 365.02 152.4366667 369.2066667 18300 17319 17141 6372.666667 17586.66667 1.37E-128 1.450280627 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005895///interleukin-5 receptor complex+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031965///nuclear membrane+++GO:0042470///melanosome+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0070062///extracellular exosome "GO:0005109///frizzled binding+++GO:0005137///interleukin-5 receptor binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0019838///growth factor binding+++GO:0042043///neurexin family protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045545///syndecan binding+++GO:0046875///ephrin receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0050839///cell adhesion molecule binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002091///negative regulation of receptor internalization+++GO:0007265///Ras protein signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0007346///regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035556///intracellular signal transduction+++GO:0042327///positive regulation of phosphorylation+++GO:0099054///presynapse assembly+++GO:1903543///positive regulation of exosomal secretion+++GO:1903553///positive regulation of extracellular exosome assembly 53379 53379 'Hnrnpa2b1' mRNA 11790 11487 10044 214.87 205.43 191.17 230.66 220.29 233.54 203.8233333 228.1633333 13873 12694 13352 11107 13306.33333 3.36E-06 0.250838927 05014///Amyotrophic lateral sclerosis "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016363///nuclear matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0070062///extracellular exosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol+++GO:1990904///ribonucleoprotein complex" GO:0001069///regulatory region RNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0035198///miRNA binding+++GO:0042802///identical protein binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0070182///DNA polymerase binding+++GO:0097157///pre-mRNA intronic binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:1990715///mRNA CDS binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0016233///telomere capping+++GO:0031053///primary miRNA processing+++GO:0044806///G-quadruplex DNA unwinding+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0050658///RNA transport+++GO:0051028///mRNA transport+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1905663///positive regulation of telomerase RNA reverse transcriptase activity+++GO:1990428///miRNA transport" 53380 53380 'Psmd10' mRNA 582 589 564 23.89 23.92 24.78 32.99 37.12 30.45 24.19666667 33.52 923 1011 825 578.3333333 919.6666667 1.87E-09 0.658289826 "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0045111///intermediate filament cytoskeleton" GO:0005515///protein binding+++GO:0008134///transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0030307///positive regulation of cell growth+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043409///negative regulation of MAPK cascade+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0070682///proteasome regulatory particle assembly+++GO:0090201///negative regulation of release of cytochrome c from mitochondria" 53381 53381 'Prdx4' mRNA 1274 1241 1271 83.1 79.95 87.85 134.7 139.22 136.36 83.63333333 136.76 2365 2384 2316 1262 2355 7.46E-33 0.88744507 04214///Apoptosis - fly GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005790///smooth endoplasmic reticulum+++GO:0005829///cytosol GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0051920///peroxiredoxin activity GO:0006979///response to oxidative stress+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0022417///protein maturation by protein folding+++GO:0030198///extracellular matrix organization+++GO:0033554///cellular response to stress+++GO:0042744///hydrogen peroxide catabolic process+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:2000255///negative regulation of male germ cell proliferation 53382 53382 'Txnl1' mRNA 1544 1651 1431 33.56 35.33 33 39.78 39.32 40.82 33.96333333 39.97333333 2105 2032 2091 1542 2076 3.09E-09 0.419000417 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0015036///disulfide oxidoreductase activity 53404 53404 'Atoh7' mRNA 9 6 8 0.36 0.24 0.34 0.04 0.04 0 0.313333333 0.026666667 1 1 0 7.666666667 0.666666667 0.026957657 -3.540075493 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0003407///neural retina development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007623///circadian rhythm+++GO:0009649///entrainment of circadian clock+++GO:0021554///optic nerve development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0043153///entrainment of circadian clock by photoperiod" 53412 53412 'Ppp1r3c' mRNA 311 345 329 6.44 7.03 7.23 7.76 7.48 9.87 6.9 8.37 431 406 531 328.3333333 456 0.002209181 0.461888553 04910///Insulin signaling pathway+++04931///Insulin resistance GO:0000164///protein phosphatase type 1 complex+++GO:0042587///glycogen granule+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019899///enzyme binding+++GO:0019903///protein phosphatase binding+++GO:0050196///[phosphorylase] phosphatase activity+++GO:2001069///glycogen binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0006470///protein dephosphorylation+++GO:0006605///protein targeting 53413 53413 'Exoc7' mRNA 1785 1734 1688 30.29 28.93 30.37 19.35 21.48 19.39 29.86333333 20.07333333 1311 1424 1272 1735.666667 1335.666667 2.86E-06 -0.388926177 04910///Insulin signaling pathway+++05132///Salmonella infection GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032584///growth cone membrane+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0090543///Flemming body GO:0005515///protein binding GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:1903441///protein localization to ciliary membrane+++GO:2000535///regulation of entry of bacterium into host cell 53414 53414 'Bysl' mRNA 494.44 465.64 503.24 6.94 6.43 7.49 9.32 8.22 9.71 6.953333333 9.083333333 764.07 658.45 771.23 487.7733333 731.25 1.10E-06 0.570454521 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005881///cytoplasmic microtubule+++GO:0030688///preribosome, small subunit precursor+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm" GO:0030515///snoRNA binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001701///in utero embryonic development+++GO:0001825///blastocyst formation+++GO:0001829///trophectodermal cell differentiation+++GO:0006364///rRNA processing+++GO:0008283///cell proliferation+++GO:0042254///ribosome biogenesis" 53415 53415 'Htatip2' mRNA 476 538 497 20.95 23.5 23.19 24.32 24.81 23.85 22.54666667 24.32666667 627 627 584 503.6666667 612.6666667 0.024583002 0.271012218 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004674///protein serine/threonine kinase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0051287///NAD binding" GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043068///positive regulation of programmed cell death+++GO:0045765///regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0051170///import into nucleus 53416 53416 'Stk39' mRNA 1317 1201 1180 25.41 22.72 24.46 15.79 14.76 15.73 24.19666667 15.42666667 948 870 901 1232.666667 906.3333333 2.39E-07 -0.455604169 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0035556///intracellular signal transduction+++GO:0036438///maintenance of lens transparency+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0043268///positive regulation of potassium ion transport+++GO:0046777///protein autophosphorylation+++GO:0050727///regulation of inflammatory response+++GO:0050801///ion homeostasis+++GO:0071476///cellular hypotonic response+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:1990869///cellular response to chemokine+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 53417 53417 'Hif3a' mRNA 183 154 127 1.39 1.15 1.02 0.86 0.99 0.8 1.186666667 0.883333333 132 147 118 154.6666667 132.3333333 0.370603628 -0.231475862 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" "GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071456///cellular response to hypoxia" 53418 53418 'B4galt2' mRNA 75 79 64 1.71 1.79 1.49 1.54 0.96 1.2 1.663333333 1.233333333 76 47 60 72.66666667 61 0.483097175 -0.264489874 00052///Galactose metabolism+++00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0003945///N-acetyllactosamine synthase activity+++GO:0004461///lactose synthase activity+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0007420///brain development+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0070085///glycosylation 53419 53419 'Corin' mRNA 324 319 300 3.66 3.57 3.57 0.55 0.5 0.41 3.6 0.486666667 56 49 40 314.3333333 48.33333333 1.20E-39 -2.713240518 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0044853///plasma membrane raft+++GO:0097060///synaptic membrane GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0034185///apolipoprotein binding+++GO:0042803///protein homodimerization activity+++GO:0097110///scaffold protein binding GO:0001822///kidney development+++GO:0001932///regulation of protein phosphorylation+++GO:0001942///hair follicle development+++GO:0003050///regulation of systemic arterial blood pressure by atrial natriuretic peptide+++GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0007565///female pregnancy+++GO:0008104///protein localization+++GO:0008217///regulation of blood pressure+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0016055///Wnt signaling pathway+++GO:0016486///peptide hormone processing+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030279///negative regulation of ossification+++GO:0030326///embryonic limb morphogenesis+++GO:0035813///regulation of renal sodium excretion+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0042733///embryonic digit morphogenesis+++GO:0043113///receptor clustering+++GO:0048813///dendrite morphogenesis+++GO:0048856///anatomical structure development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050771///negative regulation of axonogenesis+++GO:0050808///synapse organization+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0060173///limb development+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097104///postsynaptic membrane assembly+++GO:0097105///presynaptic membrane assembly+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1901631///positive regulation of presynaptic membrane organization+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering 53420 53420 'Syt5' mRNA 47 87 70 1.56 2.84 2.46 0.46 0.38 0.09 2.286666667 0.31 16 13 3 68 10.66666667 9.90E-08 -2.687345844 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0070382///exocytic vesicle+++GO:0099066///integral component of neuronal dense core vesicle membrane+++GO:1990769///proximal neuron projection "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0071277///cellular response to calcium ion 53421 53421 'Sec61a1' mRNA 7647 7672 7364 138.09 136.34 141.07 162.32 154.4 155.83 138.5 157.5166667 10342 9608 9614 7561 9854.666667 6.94E-13 0.36988252 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05110///Vibrio cholerae infection GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane GO:0005048///signal sequence binding+++GO:0005262///calcium channel activity+++GO:0008320///protein transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0043022///ribosome binding "GO:0006613///cotranslational protein targeting to membrane+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0007029///endoplasmic reticulum organization+++GO:0007275///multicellular organism development+++GO:0015031///protein transport+++GO:0016049///cell growth+++GO:0031204///posttranslational protein targeting to membrane, translocation+++GO:0034341///response to interferon-gamma+++GO:0039019///pronephric nephron development+++GO:0070588///calcium ion transmembrane transport" 53422 53422 'Ybx2' mRNA 114 119 130 4.59 4.72 5.53 2.19 2.06 2.32 4.946666667 2.19 62 56 60 121 59.33333333 8.39E-05 -1.043414131 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008289///lipid binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0045182///translation regulator activity GO:0007286///spermatid development+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0048255///mRNA stabilization+++GO:0048477///oogenesis+++GO:0048599///oocyte development+++GO:0051100///negative regulation of binding+++GO:0120162///positive regulation of cold-induced thermogenesis 53424 53424 'Tsnax' mRNA 2412 2461 2321 57.15 57.42 58.34 60.53 59.44 56.36 57.63666667 58.77666667 2938 2817 2648 2398 2801 0.002077844 0.212320841 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0031687///A2A adenosine receptor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 53598 53598 'Dctn3' mRNA 2303 2393 2300 153.24 157.57 162.53 151.88 162.74 151.35 157.78 155.3233333 2616 2730 2516 2332 2620.666667 0.038866636 0.156797656 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0048471///perinuclear region of cytoplasm" GO:0003674///molecular_function GO:0007017///microtubule-based process+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis 53599 53599 'Cd164' mRNA 6345 6798 6885 123.68 130.42 142.36 118.38 109.19 115.19 132.1533333 114.2533333 6987 6294 6583 6676 6621.333333 0.775375801 -0.026480176 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007517///muscle organ development 53600 53600 'Timm23' mRNA 1981 1966 1948 105.38 103.31 109.95 143.95 150.14 142.27 106.2133333 145.4533333 3105 3158 2967 1965 3076.666667 9.91E-21 0.634781806 04212///Longevity regulating pathway - worm GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0008320///protein transmembrane transporter activity+++GO:0019899///enzyme binding GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix 53601 53601 'Pcdh12' mRNA 3 2 4 0.03 0.02 0.04 0.23 0.47 0.32 0.03 0.34 28 56 38 3 40.66666667 1.40E-07 3.750804896 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005509///calcium ion binding GO:0005977///glycogen metabolic process+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0060711///labyrinthine layer development 53602 53602 'Hpcal1' mRNA 1460 1464.98 1519.15 50.84 49.17 55.68 29.85 29.49 30.62 51.89666667 29.98666667 989 960.08 977 1481.376667 975.36 6.75E-13 -0.616185031 GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process 53603 53603 'Tslp' mRNA 11 28 21 0.6 1.52 1.22 1.67 2.3 2.18 1.113333333 2.05 35 47 44 20 42 0.035682395 1.061634848 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005139///interleukin-7 receptor binding+++GO:0005515///protein binding GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0032722///positive regulation of chemokine production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0033005///positive regulation of mast cell activation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043066///negative regulation of apoptotic process+++GO:0050729///positive regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050832///defense response to fungus+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071654///positive regulation of chemokine (C-C motif) ligand 1 production+++GO:0071657///positive regulation of granulocyte colony-stimulating factor production+++GO:1904894///positive regulation of STAT cascade 53604 53604 'Zpbp' mRNA 59 46 37 0.83 0.79 0.57 0.3 0.39 0.35 0.73 0.346666667 19 22 27 47.33333333 22.66666667 0.017170826 -1.0669043 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0002199///zona pellucida receptor complex+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044297///cell body GO:0003674///molecular_function GO:0001675///acrosome assembly+++GO:0007339///binding of sperm to zona pellucida 53605 53605 'Nap1l1' mRNA 1305 1316 1231 20.9 21.11 21.45 32.04 30.51 31.31 21.15333333 31.28666667 2342 2173 2204 1284 2239.666667 4.84E-30 0.791029894 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0042470///melanosome+++GO:0043005///neuron projection GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0007399///nervous system development+++GO:0050769///positive regulation of neurogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation 53607 53607 'Snrpa' mRNA 1801 1765.96 1644 80.26 77.83 78.02 77.44 83.76 79.98 78.70333333 80.39333333 1988.97 2101.98 1993 1736.986667 2027.983333 0.005281944 0.213093538 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005685///U1 snRNP GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0030619///U1 snRNA binding+++GO:0042802///identical protein binding+++GO:1990446///U1 snRNP binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:1900363///regulation of mRNA polyadenylation" 53608 53608 'Map3k6' mRNA 162.14 175.27 73.97 1.61 1.79 0.8 1.3 1.26 1.26 1.4 1.273333333 134.32 135.5 126.24 137.1266667 132.02 0.888751174 -0.049678295 04010///MAPK signaling pathway GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0033554///cellular response to stress 53609 53609 'Clasrp' mRNA 1285 1087 995 27.82 22.72 23.98 14.34 15.29 15.24 24.84 14.95666667 742 733 759 1122.333333 744.6666667 3.57E-09 -0.600858761 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 53610 53610 'Nono' mRNA 3630 3885 3504 81.91 86.32 83.85 91.81 86.99 88.62 84.02666667 89.14 4679 4330 4376 3673 4461.666667 4.88E-06 0.269264842 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0042382///paraspeckles+++GO:0090575///RNA polymerase II transcription factor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0042752///regulation of circadian rhythm+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway" 53611 53611 'Vti1a' mRNA 1537.09 1555.51 1507.49 12.87 12.13 13.25 11.57 10.45 11.23 12.75 11.08333333 1684.82 1364.01 1544.53 1533.363333 1531.12 0.887104448 -0.015812772 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031201///SNARE complex+++GO:0031902///late endosome membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044306///neuron projection terminus+++GO:0048471///perinuclear region of cytoplasm GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity "GO:0006623///protein targeting to vacuole+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006896///Golgi to vacuole transport+++GO:0006906///vesicle fusion+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016189///synaptic vesicle to endosome fusion+++GO:0016192///vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0050882///voluntary musculoskeletal movement+++GO:0061025///membrane fusion+++GO:0090161///Golgi ribbon formation" 53612 53612 'Vti1b' mRNA 2098.26 2025.64 2059.73 96.6 91.82 100.92 92.85 97.31 93.64 96.44666667 94.6 2277.72 2329.79 2233.54 2061.21 2280.35 0.094591419 0.133344877 04130///SNARE interactions in vesicular transport GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0031225///anchored component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019869///chloride channel inhibitor activity "GO:0006623///protein targeting to vacuole+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006896///Golgi to vacuole transport+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:1903076///regulation of protein localization to plasma membrane" 53614 53614 'Reck' mRNA 612 663 500 7.41 7.9 6.43 4.37 4.81 5 7.246666667 4.726666667 415 447 460 591.6666667 440.6666667 7.58E-04 -0.431241876 05206///MicroRNAs in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:1990909///Wnt signalosome GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0017147///Wnt-protein binding+++GO:0030414///peptidase inhibitor activity+++GO:1904928///coreceptor activity involved in canonical Wnt signaling pathway GO:0001955///blood vessel maturation+++GO:0002040///sprouting angiogenesis+++GO:0007566///embryo implantation+++GO:0010466///negative regulation of peptidase activity+++GO:0016055///Wnt signaling pathway+++GO:0030198///extracellular matrix organization+++GO:0030336///negative regulation of cell migration+++GO:0035115///embryonic forelimb morphogenesis+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0045765///regulation of angiogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0090210///regulation of establishment of blood-brain barrier+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904684///negative regulation of metalloendopeptidase activity 53618 53618 'Fut8' mRNA 3298.06 3497.83 3218.1 74.39 77 77.56 36.02 34.33 35.67 76.31666667 35.34 1830.34 1717.24 1724.83 3337.996667 1757.47 9.92E-50 -0.937332516 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++05202///Transcriptional misregulation in cancer GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008424///glycoprotein 6-alpha-L-fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0017124///SH3 domain binding+++GO:0046921///alpha-(1->6)-fucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006491///N-glycan processing+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007585///respiratory gaseous exchange+++GO:0010468///regulation of gene expression+++GO:0016477///cell migration+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0033578///protein glycosylation in Golgi+++GO:0036071///N-glycan fucosylation+++GO:0043112///receptor metabolic process+++GO:0046368///GDP-L-fucose metabolic process+++GO:1900407///regulation of cellular response to oxidative stress 53619 53619 'Blcap' mRNA 1626 1681 1590 44.29 45.13 45.96 38 34.87 35 45.12666667 35.95666667 1603 1437 1430 1632.333333 1490 0.086549257 -0.144095132 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008150///biological_process+++GO:0030262///apoptotic nuclear changes 53620 53620 'Vamp5' mRNA 819 762 810 29.01 26.64 30.46 38.16 43.44 39.43 28.70333333 40.34333333 1235 1374 1236 797 1281.666667 6.35E-12 0.673165214 04130///SNARE interactions in vesicular transport GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0012505///endomembrane system+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031301///integral component of organelle membrane+++GO:0042581///specific granule+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0001530///lipopolysaccharide binding GO:0001878///response to yeast+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002227///innate immune response in mucosa+++GO:0002544///chronic inflammatory response+++GO:0006952///defense response+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0008284///positive regulation of cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0019731///antibacterial humoral response+++GO:0019732///antifungal humoral response+++GO:0030154///cell differentiation+++GO:0032757///positive regulation of interleukin-8 production+++GO:0035821///modification of morphology or physiology of other organism+++GO:0042742///defense response to bacterium+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0045087///innate immune response+++GO:0045766///positive regulation of angiogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051838///cytolysis by host of symbiont cells+++GO:0051873///killing by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071224///cellular response to peptidoglycan+++GO:0071347///cellular response to interleukin-1+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor 53621 53621 'Cnot4' mRNA 1668.08 1627.72 1571.97 17.66 16.48 17.78 14.34 13.75 13.58 17.30666667 13.89 1603.14 1430.99 1530 1622.59 1521.376667 0.225290822 -0.105082762 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0051865///protein autoubiquitination 53622 53622 'Krt85' mRNA 1 0 2 0.02 0 0.05 0.06 0.06 0.04 0.023333333 0.053333333 3 3 2 1 2.666666667 0.545135685 1.376022192 GO:0005882///intermediate filament+++GO:0045095///keratin filament 53623 53623 'Gria3' mRNA 310 326 285 3.44 3.4 3.21 5.04 4.88 5.03 3.35 4.983333333 531 513 521 307 521.6666667 9.90E-10 0.754709764 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04728///Dopaminergic synapse+++04730///Long-term depression+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05033///Nicotine addiction+++05202///Transcriptional misregulation in cancer GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0032281///AMPA glutamate receptor complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043083///synaptic cleft+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0001540///amyloid-beta binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0004971///AMPA glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0015276///ligand-gated ion channel activity+++GO:0030165///PDZ domain binding+++GO:0038023///signaling receptor activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0001919///regulation of receptor recycling+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0060078///regulation of postsynaptic membrane potential 53624 53624 'Cldn7' mRNA 2195 2250 2125 101.14 104.48 105.09 114.4 107.26 112.21 103.57 111.29 2756 2559 2653 2190 2656 5.29E-05 0.266389521 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion+++GO:0008284///positive regulation of cell proliferation+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0031333///negative regulation of protein complex assembly+++GO:0043066///negative regulation of apoptotic process+++GO:0045471///response to ethanol+++GO:0070830///bicellular tight junction assembly+++GO:2000147///positive regulation of cell motility 53625 53625 'B3gnt2' mRNA 1200 1330 1036 24.75 26.93 22.54 25.7 29.28 30.94 24.74 28.64 1418 1580 1667 1188.666667 1555 1.11E-04 0.381246199 00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008457///beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0007411///axon guidance+++GO:0007608///sensory perception of smell+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 53626 53626 'Insm1' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0030332///cyclin binding+++GO:0031490///chromatin DNA binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0003309///type B pancreatic cell differentiation+++GO:0003310///pancreatic A cell differentiation+++GO:0003323///type B pancreatic cell development+++GO:0003358///noradrenergic neuron development+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010564///regulation of cell cycle process+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0031018///endocrine pancreas development+++GO:0035270///endocrine system development+++GO:0042421///norepinephrine biosynthetic process+++GO:0043254///regulation of protein complex assembly+++GO:0045597///positive regulation of cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0060290///transdifferentiation+++GO:0061104///adrenal chromaffin cell differentiation+++GO:0061549///sympathetic ganglion development+++GO:0071158///positive regulation of cell cycle arrest+++GO:2000179///positive regulation of neural precursor cell proliferation 53627 53627 'Porcn' mRNA 410 425 407 12.85 13.07 13.29 7.05 6.37 7.7 13.07 7.04 260 232 278 414 256.6666667 7.55E-07 -0.702007985 04310///Wnt signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0098978///glutamatergic synapse "GO:0005515///protein binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0017147///Wnt-protein binding+++GO:1990698///palmitoleoyltransferase activity" GO:0006497///protein lipidation+++GO:0009100///glycoprotein metabolic process+++GO:0016055///Wnt signaling pathway+++GO:0018345///protein palmitoylation+++GO:0030258///lipid modification+++GO:0045234///protein palmitoleylation+++GO:0060070///canonical Wnt signaling pathway+++GO:0061355///Wnt protein secretion+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels 53761 53761 'Prrc2a' mRNA 3771 3379 2241 28.83 25.43 18.09 21.92 17.97 22.12 24.11666667 20.67 3297 2640 3222 3130.333333 3053 0.887329349 -0.039598018 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0030154///cell differentiation 53791 53791 'Tlr5' mRNA 12 16 17 0.17 0.22 0.26 0.82 0.66 0.91 0.216666667 0.796666667 67 54 74 15 65 6.04E-07 2.100194409 04620///Toll-like receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05134///Legionellosis+++05321///Inflammatory bowel disease GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0001817///regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0002224///toll-like receptor signaling pathway+++GO:0002376///immune system process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008584///male gonad development+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0034146///toll-like receptor 5 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide 53814 53814 'Oaz3' mRNA 2.3 5.38 3.17 0.16 0.36 0.23 0.12 0.28 0.06 0.25 0.153333333 2 4.63 1 3.616666667 2.543333333 0.793376262 -0.516719795 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036126///sperm flagellum GO:0005515///protein binding+++GO:0008073///ornithine decarboxylase inhibitor activity+++GO:0071532///ankyrin repeat binding GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0007283///spermatogenesis+++GO:0043086///negative regulation of catalytic activity+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0090316///positive regulation of intracellular protein transport+++GO:1902268///negative regulation of polyamine transmembrane transport 53817 53817 'Ddx39b' mRNA 2701 2771 2455 93.31 94.33 90.05 91.04 92.91 95.19 92.56333333 93.04666667 3032 3035 3076 2642.333333 3047.666667 0.002399002 0.196089433 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005687///U4 snRNP+++GO:0005688///U6 snRNP+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017070///U6 snRNA binding+++GO:0030621///U4 snRNA binding+++GO:0042802///identical protein binding+++GO:0043008///ATP-dependent protein binding+++GO:0044877///protein-containing complex binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001889///liver development+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0010501///RNA secondary structure unwinding+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0045727///positive regulation of translation+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:2000573///positive regulation of DNA biosynthetic process" 53857 53857 'Tuba8' mRNA 53.84 60.55 66.91 1.17 1.32 1.68 3.55 3.24 3.16 1.39 3.316666667 130.45 124.33 119.37 60.43333333 124.7166667 7.92E-05 1.044146756 04145///Phagosome+++04210///Apoptosis+++04530///Tight junction+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0003924///GTPase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding+++GO:0016509///long-chain-3-hydroxyacyl-CoA dehydrogenase activity+++GO:0019899///enzyme binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0006635///fatty acid beta-oxidation+++GO:0007017///microtubule-based process 53858 53858 'Rwdd2b' mRNA 52 94 62 1.4 2.49 1.77 2.95 3.38 3.58 1.886666667 3.303333333 126 141 148 69.33333333 138.3333333 3.32E-04 0.990274066 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 53859 53859 'Map3k14' mRNA 185 193 120 2.39 2.45 1.64 2.56 2.49 2.88 2.16 2.643333333 228 217 249 166 231.3333333 0.022497869 0.475274998 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04380///Osteoclast differentiation+++04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++04668///TNF signaling pathway+++04672///Intestinal immune network for IgA production+++04936///Alcoholic liver disease+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05166///Human T-cell leukemia virus 1 infection+++05169///Epstein-Barr virus infection+++05208///Chemical carcinogenesis - reactive oxygen species GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004704///NF-kappaB-inducing kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0006955///immune response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0016310///phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0038061///NIK/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051607///defense response to virus+++GO:0071260///cellular response to mechanical stimulus 53860 53860 'Septin9' mRNA 2746 2633 2617 43.96 41.6 45.14 60.3 57.58 56.82 43.56666667 58.23333333 4215 3906 3926 2665.333333 4015.666667 1.20E-20 0.578636884 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005930///axoneme+++GO:0005940///septin ring+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0031105///septin complex+++GO:0032153///cell division site+++GO:0048471///perinuclear region of cytoplasm+++GO:0097730///non-motile cilium GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0034613///cellular protein localization+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis+++GO:1902857///positive regulation of non-motile cilium assembly 53861 53861 'Zranb2' mRNA 2009 2087 2017 37.25 37.99 39.29 26.73 28.33 28.14 38.17666667 27.73333333 1664 1716 1697 2037.666667 1692.333333 2.09E-04 -0.279592206 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0001530///lipopolysaccharide binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 53867 53867 'Col5a3' mRNA 295 328 282 2.56 2.8 2.6 6.16 5.61 5.59 2.653333333 5.786666667 817 727 718 301.6666667 754 5.75E-30 1.310499529 04974///Protein digestion and absorption GO:0005581///collagen trimer+++GO:0005588///collagen type V trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005198///structural molecule activity+++GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0043394///proteoglycan binding GO:0007160///cell-matrix adhesion+++GO:0030198///extracellular matrix organization 53868 53868 'Rab25' mRNA 1315 1223 1115 78.44 72.27 70.62 39.04 40.7 42.36 73.77666667 40.7 751 765 787 1217.666667 767.6666667 6.87E-14 -0.675089169 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031143///pseudopodium+++GO:0031260///pseudopodium membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0055037///recycling endosome GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031489///myosin V binding GO:0003382///epithelial cell morphogenesis+++GO:0006887///exocytosis+++GO:0008284///positive regulation of cell proliferation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0015031///protein transport+++GO:0031268///pseudopodium organization+++GO:0060627///regulation of vesicle-mediated transport 53869 53869 'Rab11a' mRNA 4037 4144 4004 97 98.05 102.06 112.26 102.47 105.75 99.03666667 106.8266667 5373 4789 4900 4061.666667 5020.666667 1.95E-06 0.292746482 04144///Endocytosis+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption+++04972///Pancreatic secretion+++05164///Influenza A GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005802///trans-Golgi network+++GO:0005813///centrosome+++GO:0005828///kinetochore microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032154///cleavage furrow+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098837///postsynaptic recycling endosome+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0031489///myosin V binding "GO:0006887///exocytosis+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010796///regulation of multivesicular body size+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030953///astral microtubule organization+++GO:0031175///neuron projection development+++GO:0032402///melanosome transport+++GO:0032465///regulation of cytokinesis+++GO:0034394///protein localization to cell surface+++GO:0036258///multivesicular body assembly+++GO:0045773///positive regulation of axon extension+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0051223///regulation of protein transport+++GO:0051650///establishment of vesicle localization+++GO:0060627///regulation of vesicle-mediated transport+++GO:0072594///establishment of protein localization to organelle+++GO:0072659///protein localization to plasma membrane+++GO:0090150///establishment of protein localization to membrane+++GO:0090307///mitotic spindle assembly+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1990182///exosomal secretion" 53870 53870 'Cntn6' mRNA 121 103 98 1.84 1.57 1.57 0.82 1.21 0.68 1.66 0.903333333 63 90 49 107.3333333 67.33333333 0.02836591 -0.68036312 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0031225///anchored component of membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099026///anchored component of presynaptic membrane GO:0005515///protein binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007219///Notch signaling pathway+++GO:0007411///axon guidance+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0070593///dendrite self-avoidance 53871 53871 'Pkd2l2' mRNA 131.55 116.9 137 1.21 1.25 1.47 0.27 0.28 0.35 1.31 0.3 35.62 26.95 35.76 128.4833333 32.77666667 7.55E-12 -2.016647867 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0070588///calcium ion transmembrane transport 53872 53872 'Caprin1' mRNA 3564 3623 3651 44.48 44.51 49.2 61.34 57.26 55.77 46.06333333 58.12333333 5519 5015 4837 3612.666667 5123.666667 1.91E-13 0.490128027 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003723///RNA binding GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis 53881 53881 'Slc5a3' mRNA 5538.55 5534.9 5073.3 26.52 26.05 25.77 18.49 16.26 16.79 26.11333333 17.18 4446.56 3821.61 3911.6 5382.25 4059.923333 1.17E-11 -0.41874434 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005412///glucose:sodium symporter activity+++GO:0005515///protein binding+++GO:0015293///symporter activity+++GO:0015459///potassium channel regulator activity+++GO:0022857///transmembrane transporter activity+++GO:0044325///ion channel binding GO:0006020///inositol metabolic process+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007422///peripheral nervous system development+++GO:0015798///myo-inositol transport+++GO:0032409///regulation of transporter activity+++GO:0043085///positive regulation of catalytic activity+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0055085///transmembrane transport+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904659///glucose transmembrane transport+++GO:1905477///positive regulation of protein localization to membrane 53883 53883 'Celsr2' mRNA 1696 1538 1482 11.55 10.34 10.85 7.77 7.5 8.49 10.91333333 7.92 1306 1229 1376 1572 1303.666667 0.00110178 -0.281085011 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding "GO:0001764///neuron migration+++GO:0003341///cilium movement+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0021591///ventricular system development+++GO:0021999///neural plate anterior/posterior regionalization+++GO:0022407///regulation of cell-cell adhesion+++GO:0032880///regulation of protein localization+++GO:0033326///cerebrospinal fluid secretion+++GO:0048813///dendrite morphogenesis+++GO:0060271///cilium assembly+++GO:0098609///cell-cell adhesion" 53885 53885 'Nphp1' mRNA 1084 1082 1110 26.73 26.28 28.92 13.5 13.84 13.81 27.31 13.71666667 629 628 622 1092 626.3333333 1.00E-17 -0.815007459 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005929///cilium+++GO:0030054///cell junction+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0005515///protein binding GO:0007283///spermatogenesis+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0034613///cellular protein localization+++GO:0035845///photoreceptor cell outer segment organization+++GO:0048515///spermatid differentiation+++GO:0060041///retina development in camera-type eye+++GO:0090251///protein localization involved in establishment of planar polarity+++GO:1903348///positive regulation of bicellular tight junction assembly 53886 53886 'Cdkl2' mRNA 1706.52 1710.46 1503.24 17.78 17.93 18.38 5.84 5.46 6.44 18.03 5.913333333 801.4 749.37 774.44 1640.073333 775.07 1.11E-42 -1.091807816 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle 53890 53890 'Sart3' mRNA 1147 1235 461 16 17.17 7.16 5.52 11.75 8.55 13.44333333 8.606666667 430 930 684 947.6666667 681.3333333 0.477037997 -0.459828098 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005691///U6atac snRNP+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0061574///ASAP complex+++GO:0071001///U4/U6 snRNP GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0017070///U6 snRNA binding+++GO:0030621///U4 snRNA binding+++GO:0030624///U6atac snRNA binding+++GO:0042393///histone binding+++GO:1990381///ubiquitin-specific protease binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000902///cell morphogenesis+++GO:0006334///nucleosome assembly+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0048872///homeostasis of number of cells+++GO:0071425///hematopoietic stem cell proliferation+++GO:1903586///positive regulation of histone deubiquitination" 53892 53892 'Ppm1d' mRNA 527 583 170 10.03 10.92 3.43 3.44 6.08 5.43 8.126666667 4.983333333 208 359 318 426.6666667 295 0.450174355 -0.514566562 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding+++GO:0051019///mitogen-activated protein kinase binding "GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006306///DNA methylation+++GO:0006342///chromatin silencing+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0009267///cellular response to starvation+++GO:0009617///response to bacterium+++GO:0016311///dephosphorylation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0031507///heterochromatin assembly+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0045814///negative regulation of gene expression, epigenetic" 53893 53893 'Nudt5' mRNA 794.68 789.97 916 15.75 15 18.69 25.26 27.09 27.05 16.48 26.46666667 1225.24 1247.23 1226.3 833.55 1232.923333 1.75E-07 0.549736456 00230///Purine metabolism GO:0005634///nucleus GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0019144///ADP-sugar diphosphatase activity+++GO:0030515///snoRNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044715///8-oxo-dGDP phosphatase activity+++GO:0044716///8-oxo-GDP phosphatase activity+++GO:0046872///metal ion binding+++GO:0047631///ADP-ribose diphosphatase activity+++GO:0050072///m7G(5')pppN diphosphatase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006338///chromatin remodeling+++GO:0006753///nucleoside phosphate metabolic process+++GO:0009191///ribonucleoside diphosphate catabolic process+++GO:0019303///D-ribose catabolic process+++GO:0019693///ribose phosphate metabolic process+++GO:1990966///ATP generation from poly-ADP-D-ribose 53895 53895 'Clpp' mRNA 1709 1853 1618 86.86 93.01 87.25 74.93 80.47 70.85 89.04 75.41666667 1692 1772 1547 1726.666667 1670.333333 0.578138798 -0.05761499 04212///Longevity regulating pathway - worm GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0009368///endopeptidase Clp complex GO:0004175///endopeptidase activity+++GO:0004176///ATP-dependent peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0051117///ATPase binding GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0033619///membrane protein proteolysis+++GO:0051603///proteolysis involved in cellular protein catabolic process 53896 53896 'Slc7a10' mRNA 299.59 248.94 270.48 8.75 7.15 8.37 2.13 2.73 2.07 8.09 2.31 81 105.64 76.53 273.0033333 87.72333333 7.13E-16 -1.652040117 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0097440///apical dendrite GO:0005515///protein binding+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0042941///D-alanine transport+++GO:0042942///D-serine transport+++GO:0055085///transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport 53897 53897 'Gal3st1' mRNA 425 429 370 14.5 14.49 13.57 5.56 5.4 4.95 14.18666667 5.303333333 187 182 164 408 177.6666667 2.51E-16 -1.209052735 00565///Ether lipid metabolism+++00600///Sphingolipid metabolism GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006681///galactosylceramide metabolic process+++GO:0006682///galactosylceramide biosynthetic process+++GO:0007283///spermatogenesis+++GO:0009247///glycolipid biosynthetic process+++GO:0042552///myelination+++GO:0046486///glycerolipid metabolic process 53901 53901 'Rcan2' mRNA 694 785 630 11.77 12.96 11.34 3.22 3.66 2.75 12.02333333 3.21 222 250 186 703 219.3333333 5.20E-35 -1.688301747 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity GO:0006950///response to stress+++GO:0006979///response to oxidative stress+++GO:0007219///Notch signaling pathway+++GO:0007614///short-term memory+++GO:0019722///calcium-mediated signaling+++GO:0031987///locomotion involved in locomotory behavior+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0050790///regulation of catalytic activity 53902 53902 'Rcan3' mRNA 834 765 714 8.75 7.89 7.96 6.82 6.7 7.51 8.2 7.01 747 717 798 771 754 0.758811044 -0.042458958 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0019902///phosphatase binding+++GO:0031013///troponin I binding GO:0019722///calcium-mediated signaling+++GO:0050790///regulation of catalytic activity 53906 53906 'Phgr1' mRNA 1 1 2 0.15 0.15 0.32 0.13 0 0.14 0.206666667 0.09 1 0 1 1.333333333 0.666666667 0.748861207 -1.036344963 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 53945 53945 'Slc40a1' mRNA 88 97 65 1.42 1.54 1.11 5.2 6.11 5.19 1.356666667 5.5 371 426 359 83.33333333 385.3333333 7.01E-33 2.203818402 04216///Ferroptosis+++04978///Mineral absorption GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015093///ferrous iron transmembrane transporter activity+++GO:0017046///peptide hormone binding+++GO:0042802///identical protein binding GO:0002260///lymphocyte homeostasis+++GO:0003158///endothelium development+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0034395///regulation of transcription from RNA polymerase II promoter in response to iron+++GO:0034755///iron ion transmembrane transport+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048536///spleen development+++GO:0055072///iron ion homeostasis+++GO:0060345///spleen trabecula formation+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:1903988///ferrous iron export across plasma membrane 53951 53951 'Gpatch11' mRNA 804 700 735 10.25 8.71 9.92 7.3 6.32 6.39 9.626666667 6.67 656 559 559 746.3333333 591.3333333 0.002728143 -0.34965747 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome" GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0008150///biological_process 53970 53970 'Rfx5' mRNA 552 600 124 7.27 8.08 1.63 2.02 3.58 2.94 5.66 2.846666667 185 298 256 425.3333333 246.3333333 0.329026264 -0.76636648 04612///Antigen processing and presentation+++05152///Tuberculosis+++05340///Primary immunodeficiency GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 53972 53972 'Ngef' mRNA 5 15 16 0.14 0.3 0.38 0.24 0.05 0.33 0.273333333 0.206666667 14 3 14 12 10.33333333 0.83749222 -0.244044872 04360///Axon guidance GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0098978///glutamatergic synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0046875///ephrin receptor binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009987///cellular process+++GO:0030154///cell differentiation+++GO:0043087///regulation of GTPase activity+++GO:0048013///ephrin receptor signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0090630///activation of GTPase activity+++GO:0098883///synapse pruning 53975 53975 'Ddx20' mRNA 462 516 528 8.66 9.61 10.6 8.49 8.86 8.94 9.623333333 8.763333333 523 533 533 502 529.6666667 0.699593101 0.063890163 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0090571///RNA polymerase II transcription repressor complex+++GO:0097504///Gemini of coiled bodies "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0042826///histone deacetylase binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008285///negative regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048477///oogenesis+++GO:0050810///regulation of steroid biosynthetic process" 53978 53978 'Lpar2' mRNA 73 101 78 0.68 0.93 0.77 0.49 0.61 0.63 0.793333333 0.576666667 61 73 75 84 69.66666667 0.420172944 -0.277481844 04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0004930///G protein-coupled receptor activity+++GO:0030165///PDZ domain binding+++GO:0070915///lysophosphatidic acid receptor activity GO:0000187///activation of MAPK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0043410///positive regulation of MAPK cascade 54003 54003 'Nell2' mRNA 77 98 75 1.3 1.63 1.36 0.33 0.18 0.27 1.43 0.26 22 12 18 83.33333333 17.33333333 2.40E-09 -2.276674419 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043204///perikaryon GO:0005080///protein kinase C binding+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0042802///identical protein binding GO:0040008///regulation of growth+++GO:0046543///development of secondary female sexual characteristics+++GO:0046887///positive regulation of hormone secretion+++GO:0070050///neuron cellular homeostasis 54004 54004 'Diaph2' mRNA 172.9 176.96 153.02 1.12 1.09 1.02 1.54 1.54 1.54 1.076666667 1.54 278 271.04 272.01 167.6266667 273.6833333 2.73E-05 0.702709563 04810///Regulation of actin cytoskeleton GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle GO:0003779///actin binding+++GO:0031267///small GTPase binding GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007292///female gamete generation+++GO:0016043///cellular component organization+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030154///cell differentiation+++GO:0048477///oogenesis 54006 54006 'Deaf1' mRNA 1251 1245 1110 26.63 25.71 25.71 14.16 17.66 18.23 26.01666667 16.68333333 764 927 936.17 1202 875.7233333 9.91E-06 -0.464887797 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001662///behavioral fear response+++GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008542///visual learning+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048706///embryonic skeletal system development" 54120 54120 'Gipc2' mRNA 21 17 14 1.1 0.81 0.71 5.45 4.94 5.65 0.873333333 5.346666667 130 115 123 17.33333333 122.6666667 2.34E-17 2.813614672 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0008150///biological_process 54122 54122 'Uevld' mRNA 397.87 396.8 381.71 5.25 5.17 5.33 5.08 5.83 6.19 5.25 5.7 439.76 498.47 530.69 392.1266667 489.64 0.025503839 0.311284227 "GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0005975///carbohydrate metabolic process+++GO:0006464///cellular protein modification process+++GO:0015031///protein transport+++GO:0019752///carboxylic acid metabolic process 54123 54123 'Irf7' mRNA 1662 1690 1442 52.75 52.8 48.67 154.13 149.87 150.94 51.40666667 151.6466667 5574 5310 5289 1598 5391 1.20E-185 1.744705774 04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0002819///regulation of adaptive immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0016064///immunoglobulin mediated immune response+++GO:0032481///positive regulation of type I interferon production+++GO:0032606///type I interferon production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0034124///regulation of MyD88-dependent toll-like receptor signaling pathway+++GO:0034127///regulation of MyD88-independent toll-like receptor signaling pathway+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway" 54124 54124 'Cks1b' mRNA 138 134 129 12.65 12.19 12.55 57.47 59.61 55.72 12.46333333 57.6 717 724 671 133.6666667 704 3.82E-71 2.385921677 05200///Pathways in cancer+++05222///Small cell lung cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0019005///SCF ubiquitin ligase complex GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0042393///histone binding+++GO:0043130///ubiquitin binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0009790///embryo development+++GO:0044772///mitotic cell cycle phase transition+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division" 54125 54125 'Polm' mRNA 389.7 453.5 420.44 7.05 8.19 7.87 6.05 4.79 5.37 7.703333333 5.403333333 392.23 291.19 330.27 421.2133333 337.8966667 0.032146811 -0.331435643 03450///Non-homologous end-joining GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0034061///DNA polymerase activity+++GO:0046872///metal ion binding GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0030183///B cell differentiation+++GO:0071897///DNA biosynthetic process 54126 54126 'Arhgef7' mRNA 1268 1337 1124 15.19 15.82 14.29 16.14 15.01 16.74 15.1 15.96333333 1530 1392 1535 1243 1485.666667 0.00332035 0.247626203 04810///Regulation of actin cytoskeleton+++05135///Yersinia infection GO:0000322///storage vacuole+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0097431///mitotic spindle pole+++GO:0098794///postsynapse+++GO:0098982///GABA-ergic synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0043015///gamma-tubulin binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007030///Golgi organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0007399///nervous system development+++GO:0030032///lamellipodium assembly+++GO:0032092///positive regulation of protein binding+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0043615///astrocyte cell migration+++GO:0050790///regulation of catalytic activity+++GO:0060124///positive regulation of growth hormone secretion+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0099140///presynaptic actin cytoskeleton organization+++GO:1904424///regulation of GTP binding+++GO:1905833///negative regulation of microtubule nucleation 54127 54127 'Rps28' mRNA 603 613 862 155.98 160.18 237.05 225.54 233.87 267.65 184.4033333 242.3533333 984 987 1121 692.6666667 1030.666667 2.25E-04 0.552252801 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane GO:0003735///structural constituent of ribosome GO:0000028///ribosomal small subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis+++GO:0042274///ribosomal small subunit biogenesis 54128 54128 'Pmm2' mRNA 617 657 602 18.77 19.76 19.47 26.15 24.35 24.58 19.33333333 25.02666667 986 898 898 625.3333333 927.3333333 7.73E-09 0.556703025 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body GO:0004615///phosphomannomutase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0006013///mannose metabolic process+++GO:0006487///protein N-linked glycosylation+++GO:0009298///GDP-mannose biosynthetic process 54130 54130 'Actr1a' mRNA 2955 3053 3082 59.45 60.43 65.75 71.93 69.37 72.04 61.87666667 71.11333333 4114 3874 3990 3030 3992.666667 5.46E-09 0.384487334 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0030137///COPI-coated vesicle+++GO:0043209///myelin sheath+++GO:0099738///cell cortex region GO:0000166///nucleotide binding+++GO:0005524///ATP binding GO:0007283///spermatogenesis 54131 54131 'Irf3' mRNA 1368 1439 1293 41.15 44.7 42.69 43.51 42.62 43.39 42.84666667 43.17333333 1590 1568 1559 1366.666667 1572.333333 0.015241444 0.191718354 04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04936///Alcoholic liver disease+++05131///Shigellosis+++05133///Pertussis+++05135///Yersinia infection+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05203///Viral carcinogenesis+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001819///positive regulation of cytokine production+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009617///response to bacterium+++GO:0010468///regulation of gene expression+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032481///positive regulation of type I interferon production+++GO:0032496///response to lipopolysaccharide+++GO:0032606///type I interferon production+++GO:0032688///negative regulation of interferon-beta production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050689///negative regulation of defense response to virus by host+++GO:0050727///regulation of inflammatory response+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071360///cellular response to exogenous dsRNA+++GO:0097300///programmed necrotic cell death+++GO:0098586///cellular response to virus" 54132 54132 'Pdlim1' mRNA 520 509 471 20.41 19.7 19.61 28.36 27.87 31.36 19.90666667 29.19666667 830 796 888 500 838 1.27E-12 0.734404273 GO:0001725///stress fiber+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0031941///filamentous actin GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding "GO:0001666///response to hypoxia+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0010761///fibroblast migration+++GO:0030011///maintenance of cell polarity+++GO:0030036///actin cytoskeleton organization+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0043149///stress fiber assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061061///muscle structure development" 54135 54135 'Lsr' mRNA 2149 2109 2056 58.84 56.69 59.74 60.02 60.8 59.68 58.42333333 60.16666667 2517 2490 2425 2104.666667 2477.333333 0.00127408 0.223389972 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0042627///chylomicron+++GO:0061689///tricellular tight junction GO:0005515///protein binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0030228///lipoprotein particle receptor activity GO:0001889///liver development+++GO:0006897///endocytosis+++GO:0019216///regulation of lipid metabolic process+++GO:0042953///lipoprotein transport+++GO:0060856///establishment of blood-brain barrier+++GO:0061436///establishment of skin barrier+++GO:0061833///protein localization to tricellular tight junction+++GO:1904274///tricellular tight junction assembly 54137 54137 'Acrbp' mRNA 308 288 285 13.17 12.29 13.49 6.26 6.56 6.66 12.98333333 6.493333333 158 162 163 293.6666667 161 1.08E-07 -0.878500967 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0016504///peptidase activator activity GO:0001675///acrosome assembly+++GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0010952///positive regulation of peptidase activity 54138 54138 'Atxn10' mRNA 3148 3494 3254 68.61 74.96 75.23 73.95 73.9 75.17 72.93333333 74.34 3903 3809 3841 3298.666667 3851 0.001500645 0.211470214 05017///Spinocerebellar ataxia GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding GO:0007399///nervous system development+++GO:0031175///neuron projection development+++GO:0060271///cilium assembly 54139 54139 'Irf6' mRNA 2310 2427 2481 30.24 31.25 34.43 19.48 19.99 18.99 31.97333333 19.48666667 1716 1719 1619 2406 1684.666667 1.64E-11 -0.527784181 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0030216///keratinocyte differentiation+++GO:0043588///skin development+++GO:0043616///keratinocyte proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0051726///regulation of cell cycle+++GO:0060021///roof of mouth development+++GO:0060173///limb development+++GO:0060644///mammary gland epithelial cell differentiation+++GO:1904888///cranial skeletal system development" 54140 54140 'Avpr1a' mRNA 0 1 4 0 0.02 0.09 0.14 0.04 0.13 0.036666667 0.103333333 8 2 7 1.666666667 5.666666667 0.298558997 1.711943307 04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle GO:0004930///G protein-coupled receptor activity+++GO:0005000///vasopressin receptor activity+++GO:0017046///peptide hormone binding+++GO:0031894///V1A vasopressin receptor binding+++GO:0042277///peptide binding GO:0001992///regulation of systemic arterial blood pressure by vasopressin+++GO:0002125///maternal aggressive behavior+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007621///negative regulation of female receptivity+++GO:0007625///grooming behavior+++GO:0008217///regulation of blood pressure+++GO:0008284///positive regulation of cell proliferation+++GO:0010033///response to organic substance+++GO:0010035///response to inorganic substance+++GO:0010259///multicellular organism aging+++GO:0010460///positive regulation of heart rate+++GO:0014049///positive regulation of glutamate secretion+++GO:0014902///myotube differentiation+++GO:0019722///calcium-mediated signaling+++GO:0021537///telencephalon development+++GO:0030307///positive regulation of cell growth+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0032849///positive regulation of cellular pH reduction+++GO:0035176///social behavior+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042631///cellular response to water deprivation+++GO:0042711///maternal behavior+++GO:0042713///sperm ejaculation+++GO:0043084///penile erection+++GO:0045777///positive regulation of blood pressure+++GO:0045907///positive regulation of vasoconstriction+++GO:0051412///response to corticosterone+++GO:0051970///negative regulation of transmission of nerve impulse 54141 54141 'Spag5' mRNA 13 18 6 0.25 0.3 0.09 1.42 1.45 2.12 0.213333333 1.663333333 109 115 158 12.33333333 127.3333333 1.87E-18 3.367001903 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016604///nuclear body+++GO:0030496///midbody+++GO:0034451///centriolar satellite+++GO:0035253///ciliary rootlet+++GO:0035371///microtubule plus-end+++GO:0036064///ciliary basal body+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole" GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0032388///positive regulation of intracellular transport+++GO:0051294///establishment of spindle orientation+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0071539///protein localization to centrosome+++GO:0090235///regulation of metaphase plate congression+++GO:1905832///positive regulation of spindle assembly 54151 54151 'Cyhr1' mRNA 2251.76 2014.14 2036.55 86.53 76.53 83.7 57.37 52.39 52.34 82.25333333 54.03333333 1730.36 1509.65 1569.94 2100.816667 1603.316667 4.84E-07 -0.403151166 GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 54152 54152 'Dnal4' mRNA 1780 1864 1639 71.13 73.31 69.5 33.06 34.13 33.58 71.31333333 33.59 952 958 937 1761 949 4.82E-32 -0.901790323 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0042995///cell projection GO:0042802///identical protein binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding "GO:0007017///microtubule-based process+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed" 54153 54153 'Rasa4' mRNA 257 230 220 5.42 5.21 5.14 14.84 12.82 13.11 5.256666667 13.59 786 727 724 235.6666667 745.6666667 1.68E-43 1.650560763 04014///Ras signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0071277///cellular response to calcium ion 54156 54156 'Egfl6' mRNA 4 10 18 0.08 0.2 0.39 0.09 0.13 0.13 0.223333333 0.116666667 5 7 7 10.66666667 6.333333333 0.464551436 -0.782673856 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix GO:0005178///integrin binding+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization 54160 54160 'Copg2' mRNA 378.75 425.83 352.5 5.08 5.6 4.97 3.39 2.78 3.13 5.216666667 3.1 291.44 233.15 262.38 385.6933333 262.3233333 1.35E-04 -0.56613637 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030426///growth cone+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005198///structural molecule activity GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0072384///organelle transport along microtubule 54161 54161 'Copg1' mRNA 3931 4022 4088 57.17 59.89 63.74 60.33 59.44 58.75 60.26666667 59.50666667 4742 4511 4341 4013.666667 4531.333333 0.021612333 0.161245438 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005198///structural molecule activity GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051683///establishment of Golgi localization+++GO:0072384///organelle transport along microtubule 541610 541610 'Trcg1' mRNA 4 6 0 0.08 0.12 0 0.02 0 0 0.066666667 0.006666667 1 0 0 3.333333333 0.333333333 0.205219401 -3.192359097 GO:0003674///molecular_function 54167 54167 'Icos' mRNA 14 14 16 0.23 0.22 0.28 0.17 0.07 0.15 0.243333333 0.13 13 5 10 14.66666667 9.333333333 0.429488144 -0.673164488 04514///Cell adhesion molecules+++04660///T cell receptor signaling pathway+++04672///Intestinal immune network for IgA production+++05340///Primary immunodeficiency GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0002517///T cell tolerance induction+++GO:0031295///T cell costimulation+++GO:0098609///cell-cell adhesion 54169 54169 'Kat6b' mRNA 1307.97 1332.97 1134.22 6.07 6.08 5.36 3.82 3.54 3.64 5.836666667 3.666666667 1023.97 868 925 1258.386667 938.99 1.41E-06 -0.432417554 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0070776///MOZ/MORF histone acetyltransferase complex "GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0004402///histone acetyltransferase activity+++GO:0008134///transcription factor binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding" "GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor" 54170 54170 'Rragc' mRNA 342 351 274 7.29 7.36 6.19 11.59 11.68 11.08 6.946666667 11.45 626 616 579 322.3333333 607 2.13E-13 0.905229003 04140///Autophagy - animal+++04150///mTOR signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071986///Ragulator complex+++GO:1990131///Gtr1-Gtr2 GTPase complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0046982///protein heterodimerization activity+++GO:0051020///GTPase binding GO:0009267///cellular response to starvation+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0043200///response to amino acid+++GO:0071230///cellular response to amino acid stimulus+++GO:1903432///regulation of TORC1 signaling 54188 54188 'Cpsf4' mRNA 347 350 253 11.71 11.64 9.05 13.24 14.32 13.56 10.8 13.70666667 452 477 450 316.6666667 459.6666667 2.27E-04 0.532147067 03015///mRNA surveillance pathway+++05164///Influenza A GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006397///mRNA processing+++GO:0098789///pre-mRNA cleavage required for polyadenylation 54189 54189 'Rabep1' mRNA 1543 1497 1456 15.56 14.88 15.47 15.31 14.64 16.04 15.30333333 15.33 1754 1635 1777 1498.666667 1722 0.018474965 0.188432132 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity GO:0006893///Golgi to plasma membrane transport+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1903441///protein localization to ciliary membrane 54194 54194 'Akap8l' mRNA 3944 3899 4120 109.92 107 121.71 52.64 52.89 51.77 112.8766667 52.43333333 2173 2130 2058 3987.666667 2120.333333 9.52E-39 -0.925403309 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0005521///lamin binding+++GO:0016301///kinase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0007076///mitotic chromosome condensation+++GO:0010793///regulation of mRNA export from nucleus+++GO:0016310///phosphorylation+++GO:0031065///positive regulation of histone deacetylation+++GO:0033127///regulation of histone phosphorylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051081///nuclear envelope disassembly 54195 54195 'Gucy1b1' mRNA 153 200 109 2.57 3.31 1.94 2.44 2.32 2.71 2.606666667 2.49 167 155 180 154 167.3333333 0.696354825 0.117628616 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04970///Salivary secretion "GO:0005737///cytoplasm+++GO:0008074///guanylate cyclase complex, soluble+++GO:0032991///protein-containing complex+++GO:0048786///presynaptic active zone+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse" GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0004383///guanylate cyclase activity+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0020037///heme binding+++GO:0043167///ion binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047805///cytidylate cyclase activity+++GO:0051879///Hsp90 protein binding "GO:0006182///cGMP biosynthetic process+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0019934///cGMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0038060///nitric oxide-cGMP-mediated signaling pathway+++GO:0071732///cellular response to nitric oxide+++GO:0099555///trans-synaptic signaling by nitric oxide, modulating synaptic transmission" 54196 54196 'Pabpn1' mRNA 332 346.53 89.96 10.68 10.98 3.07 3.67 5.26 3.4 8.243333333 4.11 131.31 183.49 117.66 256.1633333 144.1533333 0.232823042 -0.814565569 03015///mRNA surveillance pathway+++05164///Influenza A GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0042405///nuclear inclusion body+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0043621///protein self-association+++GO:0070063///RNA polymerase binding GO:0000165///MAPK cascade+++GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0071222///cellular response to lipopolysaccharide+++GO:1904247///positive regulation of polynucleotide adenylyltransferase activity 54197 54197 'Rnf5' mRNA 2181 2190 2151 123.86 122.9 129.61 113.42 113.84 110.72 125.4566667 112.66 2291 2242 2162 2174 2231.666667 0.793254003 0.025447148 04141///Protein processing in endoplasmic reticulum GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009617///response to bacterium+++GO:0010507///negative regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031648///protein destabilization+++GO:0036503///ERAD pathway+++GO:0044257///cellular protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:2000785///regulation of autophagosome assembly 54198 54198 'Snx3' mRNA 3999 4111 3861 173.96 176.47 178.2 241.47 247.59 235.7 176.21 241.5866667 6374 6376 6018 3990.333333 6256 7.58E-30 0.637411122 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032009///early phagosome+++GO:0045335///phagocytic vesicle "GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0019903///protein phosphatase binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1901981///phosphatidylinositol phosphate binding+++GO:1905394///retromer complex binding" GO:0006783///heme biosynthetic process+++GO:0009617///response to bacterium+++GO:0010324///membrane invagination+++GO:0010976///positive regulation of neuron projection development+++GO:0015031///protein transport+++GO:0022615///protein to membrane docking+++GO:0030111///regulation of Wnt signaling pathway+++GO:0032268///regulation of cellular protein metabolic process+++GO:0032456///endocytic recycling+++GO:0033157///regulation of intracellular protein transport+++GO:0033572///transferrin transport+++GO:0034499///late endosome to Golgi transport+++GO:0042177///negative regulation of protein catabolic process+++GO:0042541///hemoglobin biosynthetic process+++GO:0046597///negative regulation of viral entry into host cell+++GO:0050765///negative regulation of phagocytosis+++GO:0051224///negative regulation of protein transport+++GO:0070676///intralumenal vesicle formation+++GO:2000642///negative regulation of early endosome to late endosome transport 54199 54199 'Ccrl2' mRNA 188 187 155 5.43 5.49 5.01 9.03 9.49 9.21 5.31 9.243333333 347 342 335 176.6666667 341.3333333 1.42E-09 0.941329117 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0042379///chemokine receptor binding+++GO:0048020///CCR chemokine receptor binding GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 54200 54200 'Sult2b1' mRNA 14 13 10 0.7 0.66 0.47 1.2 1.18 1.22 0.61 1.2 27 25 27 12.33333333 26.33333333 0.067303262 1.086552244 00140///Steroid hormone biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0004027///alcohol sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0015485///cholesterol binding+++GO:0016740///transferase activity+++GO:0050294///steroid sulfotransferase activity+++GO:1990239///steroid hormone binding GO:0000103///sulfate assimilation+++GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0051923///sulfation 54201 54201 'Zfp316' mRNA 713.15 709.78 641.72 4.69 4.59 4.41 2.59 2.96 2.92 4.563333333 2.823333333 442.08 513.68 504.85 688.2166667 486.87 1.27E-05 -0.508604313 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 54204 54204 'Septin1' mRNA 136.52 133 68.23 3.02 2.91 1.65 2.92 2.56 2.93 2.526666667 2.803333333 124.55 105 109.45 112.5833333 113 0.998591786 0.00351258 05100///Bacterial invasion of epithelial cells GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005940///septin ring+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0031105///septin complex+++GO:0032153///cell division site+++GO:0072687///meiotic spindle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0007056///spindle assembly involved in female meiosis+++GO:0017157///regulation of exocytosis+++GO:0034613///cellular protein localization+++GO:0051301///cell division+++GO:0051311///meiotic metaphase plate congression+++GO:0061640///cytoskeleton-dependent cytokinesis 54208 54208 'Arl6ip1' mRNA 6147 6739 6366 162.8 175.79 178.85 192.44 191.35 191.19 172.48 191.66 8355 8111 8035 6417.333333 8167 8.39E-09 0.335546452 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002038///positive regulation of L-glutamate import across plasma membrane+++GO:0006613///cotranslational protein targeting to membrane+++GO:0006915///apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:1903371///regulation of endoplasmic reticulum tubular network organization+++GO:1990809///endoplasmic reticulum tubular network membrane organization 54214 54214 'Golga4' mRNA 1661 1600 1288 11.48 10.84 9.47 8.09 7.49 8.1 10.59666667 7.893333333 1348 1216 1305 1516.333333 1289.666667 0.009239874 -0.241645015 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0031267///small GTPase binding+++GO:0051020///GTPase binding GO:0043001///Golgi to plasma membrane protein transport+++GO:0045773///positive regulation of axon extension+++GO:0048193///Golgi vesicle transport 54215 54215 'Cd160' mRNA 1 3 3 0.02 0.07 0.07 0.25 0.16 0.24 0.053333333 0.216666667 13 8 12 2.333333333 11 0.042127146 2.217685875 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0023024///MHC class I protein complex binding+++GO:0032393///MHC class I receptor activity+++GO:0032394///MHC class Ib receptor activity+++GO:0032397///activating MHC class I receptor activity "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002385///mucosal immune response+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002819///regulation of adaptive immune response+++GO:0002857///positive regulation of natural killer cell mediated immune response to tumor cell+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016525///negative regulation of angiogenesis+++GO:0031295///T cell costimulation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045087///innate immune response+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:1900280///negative regulation of CD4-positive, alpha-beta T cell costimulation+++GO:1905675///negative regulation of adaptive immune memory response+++GO:2000353///positive regulation of endothelial cell apoptotic process" 54216 54216 'Pcdh7' mRNA 729 726 640 4.69 4.53 4.32 1.7 1.41 1.74 4.513333333 1.616666667 254 215 258 698.3333333 242.3333333 4.63E-36 -1.537444065 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 54217 54217 'Rpl36' mRNA 2040 1895 2248 488.07 460.23 577.18 361.8 389.46 430.4 508.4933333 393.8866667 1689 1772 1928 2061 1796.333333 0.04506137 -0.213824951 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation 54218 54218 'B3galt4' mRNA 158 145 138 5.88 5.32 5.45 6.41 6.3 7.19 5.55 6.633333333 198 190 215 147 201 0.026578515 0.440705998 00604///Glycosphingolipid biosynthesis - ganglio series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047915///ganglioside galactosyltransferase activity" GO:0001574///ganglioside biosynthetic process+++GO:0006486///protein glycosylation 54219 54219 'Cd320' mRNA 652 636 634 16.63 15.98 17.16 19.08 18.84 20.21 16.59 19.37666667 860 829 882 640.6666667 857 4.76E-05 0.407546583 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0008083///growth factor activity+++GO:0031419///cobalamin binding+++GO:0038024///cargo receptor activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0009235///cobalamin metabolic process+++GO:0015889///cobalamin transport+++GO:0030656///regulation of vitamin metabolic process+++GO:0030890///positive regulation of B cell proliferation+++GO:0031296///B cell costimulation 54324 54324 'Arhgef5' mRNA 482 535 480 4.75 5.18 5.02 4.59 5.23 4.58 4.983333333 4.8 536 597 518 499 550.3333333 0.355344795 0.131253266 GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0071944///cell periphery GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding GO:0002408///myeloid dendritic cell chemotaxis+++GO:0030036///actin cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051493///regulation of cytoskeleton organization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0071803///positive regulation of podosome assembly+++GO:0090630///activation of GTPase activity+++GO:1904591///positive regulation of protein import 54325 54325 'Elovl1' mRNA 2636 2780 2627 79.12 83.01 84.39 123.19 118.3 121.33 82.17333333 120.94 4566 4260 4343 2681 4389.666667 5.41E-32 0.699142276 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0061436///establishment of skin barrier" 54326 54326 'Elovl2' mRNA 4 13 6 0.06 0.18 0.09 0.18 0.19 0.38 0.11 0.25 15 15 30 7.666666667 20 0.076581232 1.381585894 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity" "GO:0000038///very long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0042761///very long-chain fatty acid biosynthetic process" 54338 54338 'Slc23a2' mRNA 2485 2597 2327 22.09 23.11 21.79 15.2 14.55 15.32 22.33 15.02333333 1980 1854 1922 2469.666667 1918.666667 1.18E-08 -0.375025525 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0043229///intracellular organelle GO:0005215///transporter activity+++GO:0008520///L-ascorbate:sodium symporter activity+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0009636///response to toxic substance+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0019852///L-ascorbic acid metabolic process+++GO:0030324///lung development+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070837///dehydroascorbic acid transport+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0071361///cellular response to ethanol+++GO:1901215///negative regulation of neuron death+++GO:1903861///positive regulation of dendrite extension 54342 54342 'Gnpnat1' mRNA 774.3 878.14 818.28 17.4 19.63 19.66 19.4 19.9 18.2 18.89666667 19.16666667 953.87 962.13 878.5 823.5733333 931.5 0.129413347 0.165469477 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane "GO:0004343///glucosamine 6-phosphate N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042802///identical protein binding+++GO:0048029///monosaccharide binding" GO:0001889///liver development+++GO:0006041///glucosamine metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:1990830///cellular response to leukemia inhibitory factor 54343 54343 'Atf7ip' mRNA 2688 2575 2180 19.36 18.07 16.42 15.52 13.15 14.35 17.95 14.34 2309 2000 2088.54 2481 2132.513333 0.004190974 -0.228054095 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0016887///ATPase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006306///DNA methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031647///regulation of protein stability+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045898///regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0050821///protein stabilization+++GO:0090309///positive regulation of methylation-dependent chromatin silencing" 54351 54351 'Elp5' mRNA 1158 1165 1204 49.52 48.07 54.11 48.38 50.44 51.24 50.56666667 50.02 1324 1332.07 1349 1175.666667 1335.023333 0.068146849 0.170294246 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033588///Elongator holoenzyme complex GO:0000049///tRNA binding GO:0002098///tRNA wobble uridine modification+++GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0030335///positive regulation of cell migration 54352 54352 'Irx5' mRNA 137 136 109 3.19 3.12 2.69 2.53 2.26 2.44 3 2.41 125 109 117 127.3333333 117 0.652036678 -0.130953879 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0002027///regulation of heart rate+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0010468///regulation of gene expression+++GO:0030182///neuron differentiation+++GO:0042551///neuron maturation+++GO:0048468///cell development+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0050896///response to stimulus+++GO:0060040///retinal bipolar neuron differentiation" 54353 54353 'Skap2' mRNA 266 225 202 9.47 7.9 7.63 43.9 42.47 41.91 8.333333333 42.76 1417 1338 1309 231 1354.666667 8.91E-123 2.54213982 05135///Yersinia infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding GO:0008285///negative regulation of cell proliferation+++GO:0042113///B cell activation 54354 54354 'Rassf5' mRNA 50.89 62.26 47.97 0.85 1.03 0.84 8.1 9.1 8.6 0.906666667 8.6 536.43 586.98 549.27 53.70666667 557.56 1.44E-81 3.385142517 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04218///Cellular senescence+++04670///Leukocyte transendothelial migration+++05200///Pathways in cancer+++05223///Non-small cell lung cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0042981///regulation of apoptotic process+++GO:1900180///regulation of protein localization to nucleus 54357 54357 'Epb41l4b' mRNA 520 541 550 8.75 8.73 9.58 6.4 6.48 6.38 9.02 6.42 427 410 398 537 411.6666667 0.001457577 -0.396871493 04530///Tight junction GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0045177///apical part of cell GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding GO:0010628///positive regulation of gene expression+++GO:0031032///actomyosin structure organization+++GO:0042060///wound healing+++GO:0045785///positive regulation of cell adhesion+++GO:0051549///positive regulation of keratinocyte migration 54364 54364 'Rpp30' mRNA 360 361 389 19.27 19.09 22.09 24.35 24.97 24.42 20.15 24.58 522 522 506 370 516.6666667 3.08E-04 0.467875144 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 54366 54366 'Ctnnal1' mRNA 1776 1748 1805 26.27 25.43 28.22 19.61 19.37 20.44 26.64 19.80666667 1530 1480 1546 1776.333333 1518.666667 0.003415775 -0.239374072 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0045296///cadherin binding+++GO:0051015///actin filament binding GO:0007155///cell adhesion+++GO:0007266///Rho protein signal transduction 54367 54367 'Zfp326' mRNA 499 531 458 10.49 10.94 10.27 10.3 10.16 10.59 10.56666667 10.35 566 535 559 496 553.3333333 0.24947971 0.147723822 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044609///DBIRD complex GO:0000993///RNA polymerase II complex binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0043484///regulation of RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated" 54368 54368 'Gp9' mRNA 3 1 7 0.09 0.03 0.21 0.13 0.03 0.34 0.11 0.166666667 2 1 7 3.666666667 3.333333333 0.922565179 -0.179026395 04512///ECM-receptor interaction+++04611///Platelet activation+++04640///Hematopoietic cell lineage GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008150///biological_process 54369 54369 'Nme6' mRNA 325 435 397 19.98 26.18 25.59 19.38 20.22 21.62 23.91666667 20.40666667 362 370 397 385.6666667 376.3333333 0.824047303 -0.047485771 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0016310///phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0045839///negative regulation of mitotic nuclear division 54371 54371 'Chst2' mRNA 547 575 480 4.64 4.8 4.32 1.43 1.17 1.28 4.586666667 1.293333333 194 155 168 534 172.3333333 1.40E-31 -1.642003362 00533///Glycosaminoglycan biosynthesis - keratan sulfate GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0006954///inflammatory response+++GO:1903238///positive regulation of leukocyte tethering or rolling 54373 54373 'Prss16' mRNA 10 6 1 0.26 0.16 0.03 1.21 1.05 1.04 0.15 1.1 53 45 44 5.666666667 47.33333333 2.93E-07 3.062488685 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0031410///cytoplasmic vesicle GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 54375 54375 'Azin1' mRNA 2686.26 2662.38 2587.31 26.91 26.72 27.77 26.2 28.53 26.29 27.13333333 27.00666667 2920.47 3103.13 2821.01 2645.316667 2948.203333 0.055145685 0.145192521 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome GO:0003824///catalytic activity+++GO:0004586///ornithine decarboxylase activity+++GO:0042978///ornithine decarboxylase activator activity GO:0006595///polyamine metabolic process+++GO:0006596///polyamine biosynthetic process+++GO:0010825///positive regulation of centrosome duplication+++GO:0033387///putrescine biosynthetic process from ornithine+++GO:0042177///negative regulation of protein catabolic process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:1902269///positive regulation of polyamine transmembrane transport 54377 54377 'Cacng4' mRNA 672 699 588 9.99 10.22 9.27 3.84 3.49 3.89 9.826666667 3.74 297 264 292 653 284.3333333 4.82E-24 -1.209169291 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0036477///somatodendritic compartment+++GO:0044297///cell body+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity+++GO:0016247///channel regulator activity+++GO:0035255///ionotropic glutamate receptor binding "GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0019226///transmission of nerve impulse+++GO:0034765///regulation of ion transmembrane transport+++GO:0042220///response to cocaine+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070588///calcium ion transmembrane transport+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099590///neurotransmitter receptor internalization+++GO:2000311///regulation of AMPA receptor activity+++GO:2000969///positive regulation of AMPA receptor activity" 54380 54380 'Smarcal1' mRNA 717 658 707 9.38 8.51 10.27 6.34 7.03 7.34 9.386666667 6.903333333 494 530 554 694 526 5.24E-04 -0.412443225 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0035861///site of double-strand break+++GO:0043596///nuclear replication fork GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0036310///annealing helicase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0048478///replication fork protection 54381 54381 'Cpq' mRNA 2893 3019 2924 85.96 88.43 92.21 41.08 40.24 39.08 88.86666667 40.13333333 1590 1519 1463 2945.333333 1524 2.12E-44 -0.963198117 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle GO:0004177///aminopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation+++GO:0042246///tissue regeneration+++GO:0043171///peptide catabolic process 54383 54383 'Phc2' mRNA 834 780 670 15.14 14.24 13.57 16.33 17.68 17.69 14.31666667 17.23333333 894 929 920 761.3333333 914.3333333 0.014216023 0.255963187 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031519///PcG protein complex+++GO:0031982///vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0035102///PRC1 complex "GO:0001962///alpha-1,3-galactosyltransferase activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047276///N-acetyllactosaminide 3-alpha-galactosyltransferase activity" "GO:0005975///carbohydrate metabolic process+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030259///lipid glycosylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071287///cellular response to manganese ion" 54384 54384 'Mtmr7' mRNA 899.93 935.33 853.57 12.38 12.85 12.93 2.66 2.33 2.4 12.72 2.463333333 210.1 191.57 191.49 896.2766667 197.72 1.18E-80 -2.193700944 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016312///inositol bisphosphate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0052866///phosphatidylinositol phosphate phosphatase activity GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation 54387 54387 'Mcm3ap' mRNA 705.01 749.37 715.93 6.72 6.94 7.24 4.61 4.81 4.7 6.966666667 4.706666667 562.29 555 549 723.4366667 555.43 2.32E-04 -0.39256591 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0044615///nuclear pore nuclear basket+++GO:0070390///transcription export complex 2 "GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0004402///histone acetyltransferase activity+++GO:0010484///H3 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding" GO:0002376///immune system process+++GO:0006406///mRNA export from nucleus+++GO:0015031///protein transport+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0016573///histone acetylation+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0034728///nucleosome organization+++GO:0043966///histone H3 acetylation+++GO:0051028///mRNA transport 54388 54388 'H1f9' mRNA 2 0 1 0.15 0 0.08 0 0 0 0.076666667 0 0 0 0 1 0 0.60428608 -2.461629596 GO:0000786///nucleosome+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0042393///histone binding GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0016584///nucleosome positioning+++GO:0030154///cell differentiation+++GO:0030261///chromosome condensation+++GO:0031507///heterochromatin assembly+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination 54390 54390 'Sit1' mRNA 0 4 3 0 0.2 0.16 0.45 0.27 0.23 0.12 0.316666667 10 6 5 2.333333333 7 0.263898349 1.56403739 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019900///kinase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0043029///T cell homeostasis+++GO:0050863///regulation of T cell activation 54391 54391 'Rfk' mRNA 4684 4820 4721 105.21 106.59 112.49 84.21 81.95 82.34 108.0966667 82.83333333 4312 4098 4082 4741.666667 4164 0.001173045 -0.200231563 00740///Riboflavin metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008531///riboflavin kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006771///riboflavin metabolic process+++GO:0006915///apoptotic process+++GO:0009231///riboflavin biosynthetic process+++GO:0009398///FMN biosynthetic process+++GO:0016310///phosphorylation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0072593///reactive oxygen species metabolic process 54392 54392 'Ncapg' mRNA 5.83 8.9 12.44 0.09 0.13 0.19 2.81 2.69 2.87 0.136666667 2.79 220.97 206.42 217.85 9.056666667 215.08 6.79E-38 4.670126485 "GO:0000779///condensed chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0005694///chromosome+++GO:0005737///cytoplasm" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0051301///cell division 54393 54393 'Gabbr1' mRNA 382 392 287 4.03 4.1 3.13 2.06 1.81 2.12 3.753333333 1.996666667 246 202 236 353.6666667 228 7.98E-05 -0.64068341 04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04727///GABAergic synapse+++04742///Taste transduction+++04915///Estrogen signaling pathway+++04929///GnRH secretion+++05032///Morphine addiction GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0031966///mitochondrial membrane+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane+++GO:1902710///GABA receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:1990430///extracellular matrix protein binding GO:0001649///osteoblast differentiation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0014048///regulation of glutamate secretion+++GO:0014049///positive regulation of glutamate secretion+++GO:0014053///negative regulation of gamma-aminobutyric acid secretion+++GO:0032811///negative regulation of epinephrine secretion+++GO:0033602///negative regulation of dopamine secretion+++GO:0050805///negative regulation of synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060124///positive regulation of growth hormone secretion 54394 54394 'Crlf3' mRNA 1126 1243 1198 26.32 28.66 29.72 27.49 31.77 28.06 28.23333333 29.10666667 1350 1524 1335 1189 1403 0.023358546 0.227345688 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003677///DNA binding+++GO:0042802///identical protein binding "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest" 54396 54396 'Irgm2' mRNA 1043.83 1055.92 1150.84 16.15 16.07 18.89 22.37 22.54 18.81 17.03666667 21.24 1664.14 1637.62 1355.07 1083.53 1552.276667 1.29E-06 0.504328231 05145///Toxoplasmosis GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0020003///symbiont-containing vacuole GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0050700///CARD domain binding+++GO:0051434///BH3 domain binding GO:0000045///autophagosome assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006952///defense response+++GO:0009617///response to bacterium+++GO:0010508///positive regulation of autophagy+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0031648///protein destabilization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034341///response to interferon-gamma+++GO:0035458///cellular response to interferon-beta+++GO:0042742///defense response to bacterium+++GO:0042832///defense response to protozoan+++GO:0043254///regulation of protein complex assembly+++GO:0045087///innate immune response+++GO:0050821///protein stabilization+++GO:0050829///defense response to Gram-negative bacterium+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0061635///regulation of protein complex stability+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:0098586///cellular response to virus+++GO:1901098///positive regulation of autophagosome maturation 54397 54397 'Ppt2' mRNA 504 470 234 16.9 15.43 8.32 12.34 10.23 12.44 13.55 11.67 425 345 411 402.6666667 393.6666667 0.905819236 -0.031501185 00062///Fatty acid elongation+++01212///Fatty acid metabolism+++04142///Lysosome GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0098599///palmitoyl hydrolase activity GO:0098734///macromolecule depalmitoylation 54399 54399 'Bet1l' mRNA 946 966 1018 35.24 35.6 40.35 38.65 41.36 39.57 37.06333333 39.86 1182 1237 1172 976.6666667 1197 0.004303765 0.280097043 04130///SNARE interactions in vesicular transport GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0031201///SNARE complex GO:0005484///SNAP receptor activity "GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:2000156///regulation of retrograde vesicle-mediated transport, Golgi to ER" 54401 54401 'Ywhab' mRNA 5491 5686 5265 109.3 111.38 111.17 131.13 138.58 133.82 110.6166667 134.51 7580 7829 7491 5480.666667 7633.333333 1.50E-17 0.467283882 04013///MAPK signaling pathway - fly+++04110///Cell cycle+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04212///Longevity regulating pathway - worm+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++05160///Hepatitis C+++05161///Hepatitis B+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm GO:0004497///monooxygenase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding+++GO:0050815///phosphoserine residue binding+++GO:0051219///phosphoprotein binding "GO:0006605///protein targeting+++GO:0007165///signal transduction+++GO:0034613///cellular protein localization+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043085///positive regulation of catalytic activity+++GO:0043086///negative regulation of catalytic activity+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051220///cytoplasmic sequestering of protein" 54402 54402 'Stk19' mRNA 357 362 389 20.8 20.85 24.05 23.17 26.58 26.75 21.9 25.5 456 510 509 369.3333333 491.6666667 0.004034502 0.399895382 GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0046579///positive regulation of Ras protein signal transduction 54403 54403 'Slc4a4' mRNA 826 705 685 5.77 4.83 5.1 1.1 1.11 0.97 5.233333333 1.06 182 177 154 738.6666667 171 1.41E-56 -2.121826525 04964///Proximal tubule bicarbonate reclamation+++04972///Pancreatic secretion+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005452///inorganic anion exchanger activity+++GO:0005515///protein binding+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0006885///regulation of pH+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0042391///regulation of membrane potential+++GO:0045821///positive regulation of glycolytic process+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport 54405 54405 'Ndufa1' mRNA 1797 1807 2329 310.74 312.68 427.64 342.45 352.27 375.35 350.3533333 356.69 2251 2246 2373 1977.666667 2290 0.119975682 0.192278583 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain GO:0032981///mitochondrial respiratory chain complex I assembly 54409 54409 'Ramp2' mRNA 468 411 345 35.6 30.96 27.85 41.84 47.04 47.03 31.47 45.30333333 630 690 684 408 668 2.08E-08 0.704416453 04270///Vascular smooth muscle contraction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0150057///amylin receptor complex 2+++GO:1903143///adrenomedullin receptor complex GO:0001605///adrenomedullin receptor activity+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity+++GO:1990409///adrenomedullin binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001666///response to hypoxia+++GO:0002040///sprouting angiogenesis+++GO:0006816///calcium ion transport+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0008217///regulation of blood pressure+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0031623///receptor internalization+++GO:0032092///positive regulation of protein binding+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0032870///cellular response to hormone stimulus+++GO:0034333///adherens junction assembly+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043116///negative regulation of vascular permeability+++GO:0045766///positive regulation of angiogenesis+++GO:0070830///bicellular tight junction assembly+++GO:0070831///basement membrane assembly+++GO:0072659///protein localization to plasma membrane+++GO:0097084///vascular smooth muscle cell development+++GO:0097647///amylin receptor signaling pathway+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:2001214///positive regulation of vasculogenesis 54411 54411 'Atp6ap1' mRNA 7704.24 8320 8003 198.26 210.71 218.32 265.08 264.13 256.19 209.0966667 261.8 11844 11534.22 11090.3 8009.08 11489.50667 7.95E-19 0.50792161 00190///Oxidative phosphorylation+++04142///Lysosome+++04145///Phagosome+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05152///Tuberculosis+++05161///Hepatitis B+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0033181///plasma membrane proton-transporting V-type ATPase complex" GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0031267///small GTPase binding GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0008219///cell death+++GO:0030641///regulation of cellular pH+++GO:0036295///cellular response to increased oxygen levels+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0045851///pH reduction+++GO:0045921///positive regulation of exocytosis+++GO:0051656///establishment of organelle localization+++GO:0070070///proton-transporting V-type ATPase complex assembly+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1902600///proton transmembrane transport+++GO:2001206///positive regulation of osteoclast development 54418 54418 'Fmn2' mRNA 339 376 286 2.52 2.83 2.28 1.66 1.21 1.6 2.543333333 1.49 255 183 238 333.6666667 225.3333333 7.74E-04 -0.575901699 04320///Dorso-ventral axis formation GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0008017///microtubule binding GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045010///actin nucleation+++GO:0046907///intracellular transport+++GO:0048477///oogenesis+++GO:0051017///actin filament bundle assembly+++GO:0051295///establishment of meiotic spindle localization+++GO:0051758///homologous chromosome movement towards spindle pole involved in homologous chromosome segregation+++GO:0070649///formin-nucleated actin cable assembly+++GO:0071456///cellular response to hypoxia+++GO:2000781///positive regulation of double-strand break repair 54419 54419 'Cldn6' mRNA 730 760 744 28.84 29.88 31.02 91.61 90.43 92.89 29.91333333 91.64333333 2671 2571 2619 744.6666667 2620.333333 5.58E-130 1.802842249 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction GO:0001618///virus receptor activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0045216///cell-cell junction organization+++GO:0046718///viral entry into host cell+++GO:0070830///bicellular tight junction assembly 54420 54420 'Cldn8' mRNA 5595 6004 5600 132.88 140.41 141.09 78.02 75.95 76.09 138.1266667 76.68666667 3778 3591 3567 5733 3645.333333 2.46E-31 -0.665219919 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 54422 54422 'Barhl1' mRNA 288 240 216 5.79 4.42 4.61 0.51 0.58 0.63 4.94 0.573333333 31 36 32 248 33 2.56E-33 -2.917846891 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001764///neuron migration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007605///sensory perception of sound+++GO:0030901///midbrain development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 54426 54426 'Hgfac' mRNA 7 13 9 0.2 0.36 0.27 0.04 0.14 0.03 0.276666667 0.07 1 6 1 9.666666667 2.666666667 0.118131969 -1.856391285 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0031638///zymogen activation 54427 54427 'Dnmt3l' mRNA 0 0 4 0 0 0.17 0.39 0.35 0.17 0.056666667 0.303333333 8 8 5 1.333333333 7 0.135511489 2.335874399 GO:0000792///heterochromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035098///ESC/E(Z) complex GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0030234///enzyme regulator activity+++GO:0046872///metal ion binding "GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0006306///DNA methylation+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0010468///regulation of gene expression+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0032259///methylation+++GO:0032776///DNA methylation on cytosine+++GO:0043046///DNA methylation involved in gamete generation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation+++GO:0050790///regulation of catalytic activity+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0071514///genetic imprinting+++GO:1905642///negative regulation of DNA methylation+++GO:1905643///positive regulation of DNA methylation" 54445 54445 'Unc93b1' mRNA 749 790 775 18.71 19.32 20.44 144.48 140.39 141.95 19.49 142.2733333 6680 6332 6356 771.3333333 6456 0 3.05277776 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0045335///phagocytic vesicle GO:0005515///protein binding+++GO:0035325///Toll-like receptor binding GO:0000902///cell morphogenesis+++GO:0002224///toll-like receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006886///intracellular protein transport+++GO:0019882///antigen processing and presentation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 54446 54446 'Nfat5' mRNA 3837.87 3838.13 2998 12.49 12.01 8.93 5.36 5.47 5.85 11.14333333 5.56 2214.79 1957.02 2228.23 3558 2133.346667 7.44E-21 -0.745548267 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001816///cytokine production+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006970///response to osmotic stress+++GO:0010628///positive regulation of gene expression+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0071345///cellular response to cytokine stimulus+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell" 54447 54447 'Asah2' mRNA 113 126 98 1.25 1.37 1.15 1.44 1.33 1.22 1.256666667 1.33 149 135 123 112.3333333 135.6666667 0.307403972 0.263151292 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0046872///metal ion binding+++GO:0070774///phytoceramidase activity+++GO:0071633///dihydroceramidase activity+++GO:0102121///ceramidase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006915///apoptotic process+++GO:0007346///regulation of mitotic cell cycle+++GO:0010033///response to organic substance+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0044241///lipid digestion+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0046514///ceramide catabolic process+++GO:0071345///cellular response to cytokine stimulus+++GO:2001234///negative regulation of apoptotic signaling pathway 54451 54451 'Cpsf3' mRNA 1537 1632 1503 36.33 38.56 37.22 34.25 34.75 34.61 37.37 34.53666667 1658 1648 1606 1557.333333 1637.333333 0.506493107 0.061164877 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004534///5'-3' exoribonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 544678 544678 'Cfap74' mRNA 692.01 712.1 603.99 9.43 9.72 8.97 2.37 2.18 2.5 9.373333333 2.35 161.6 159 172.85 669.3666667 164.4833333 4.98E-55 -2.037288522 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process+++GO:0035082///axoneme assembly 544696 544696 'Tbc1d32' mRNA 407 418 378 3.02 3.03 3 1.21 1.31 1.2 3.016666667 1.24 185 190 179 401 184.6666667 7.65E-15 -1.128989665 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0001822///kidney development+++GO:0002088///lens development in camera-type eye+++GO:0003406///retinal pigment epithelium development+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0021532///neural tube patterning+++GO:0021915///neural tube development+++GO:0035082///axoneme assembly+++GO:0042733///embryonic digit morphogenesis+++GO:0043010///camera-type eye development+++GO:0060021///roof of mouth development+++GO:0060041///retina development in camera-type eye+++GO:0060271///cilium assembly+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0061512///protein localization to cilium+++GO:1905515///non-motile cilium assembly 544717 544717 '1190007I07Rik' mRNA 191 176 176 20.28 18.57 20.53 12.54 15.78 16.83 19.79333333 15.05 134 168 176 181 159.3333333 0.420689482 -0.193607713 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0034551///mitochondrial respiratory chain complex III assembly 54473 54473 'Tollip' mRNA 3117 3175 3253 44.78 44.8 49.58 35.38 34.27 33.47 46.38666667 34.37333333 2836 2687 2598 3181.666667 2707 6.99E-04 -0.247010292 04620///Toll-like receptor signaling pathway GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm "GO:0005150///interleukin-1, type I receptor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032183///SUMO binding+++GO:0035325///Toll-like receptor binding+++GO:0043130///ubiquitin binding" GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0030855///epithelial cell differentiation+++GO:0033235///positive regulation of protein sumoylation+++GO:0036010///protein localization to endosome+++GO:0045087///innate immune response+++GO:0070498///interleukin-1-mediated signaling pathway 544763 544763 'Hbq1b' mRNA 2 1 2 0.19 0.09 0.2 0.08 0 0 0.16 0.026666667 1 0 0 1.666666667 0.333333333 0.460918474 -2.238837931 GO:0005833///hemoglobin complex+++GO:0031838///haptoglobin-hemoglobin complex GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0031720///haptoglobin binding+++GO:0043177///organic acid binding+++GO:0046872///metal ion binding GO:0015671///oxygen transport+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification 544791 544791 'Myh13' mRNA 163 186.91 167 1.47 1.65 1.59 0.15 0.05 0.16 1.57 0.12 19 6 20 172.3033333 15 4.42E-26 -3.533498112 GO:0016459///myosin complex+++GO:0030016///myofibril GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0009267///cellular response to starvation 544817 544817 'Arhgap27' mRNA 400 424 401 5.56 6.09 6.22 6.55 7.09 7.37 5.956666667 7.003333333 535 561 549 408.3333333 548.3333333 6.74E-04 0.414221426 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007165///signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity 54483 54483 'Mefv' mRNA 4 1 10 0.07 0.02 0.19 1.12 1.25 0.77 0.093333333 1.046666667 76 81 54 5 70.33333333 2.06E-11 3.787713388 04621///NOD-like receptor signaling pathway+++05135///Yersinia infection GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0030027///lamellipodium+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032651///regulation of interleukin-1 beta production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032695///negative regulation of interleukin-12 production+++GO:0034341///response to interferon-gamma+++GO:0045087///innate immune response+++GO:0050728///negative regulation of inflammatory response+++GO:0071641///negative regulation of macrophage inflammatory protein 1 alpha production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1904270///pyroptosome complex assembly+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 54484 54484 'Mkrn1' mRNA 2756 2798 1311 53.53 52.95 27.59 23.25 29.71 26.84 44.69 26.6 1357 1707 1529 2288.333333 1531 0.125347937 -0.572601179 GO:0003682///chromatin binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:1990830///cellular response to leukemia inhibitory factor 544848 544848 'Gm5784' mRNA 149.92 122.29 94.81 2.92 2.27 1.81 1.4 0.95 1.25 2.333333333 1.2 87.81 58.14 69.55 122.34 71.83333333 0.005966782 -0.778818721 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54485 54485 'Dll4' mRNA 130 149 148 2.05 2.31 2.49 1.33 1.15 1.25 2.283333333 1.243333333 97 82 88 142.3333333 89 0.003804035 -0.691852816 01522///Endocrine resistance+++04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05224///Breast cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005112///Notch binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001974///blood vessel remodeling+++GO:0003208///cardiac ventricle morphogenesis+++GO:0003209///cardiac atrium morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003344///pericardium morphogenesis+++GO:0007154///cell communication+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007601///visual perception+++GO:0008285///negative regulation of cell proliferation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030217///T cell differentiation+++GO:0035912///dorsal aorta morphogenesis+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0050767///regulation of neurogenesis+++GO:0050896///response to stimulus+++GO:0060579///ventral spinal cord interneuron fate commitment+++GO:0061074///regulation of neural retina development+++GO:0061314///Notch signaling involved in heart development+++GO:0072554///blood vessel lumenization+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation 54486 54486 'Hpgds' mRNA 78.47 97.31 84.38 1.86 1.88 2.06 16.87 18.63 17.24 1.933333333 17.58 868.08 850.01 785.97 86.72 834.6866667 4.83E-114 3.261664478 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++05204///Chemical carcinogenesis - DNA adducts GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000287///magnesium ion binding+++GO:0004364///glutathione transferase activity+++GO:0004667///prostaglandin-D synthase activity+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0042803///protein homodimerization activity GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:2000255///negative regulation of male germ cell proliferation 544864 544864 'Gm5785' mRNA 150.03 121.48 136.75 1.24 0.99 1.2 0.61 0.82 0.7 1.143333333 0.71 84.96 111.97 95.13 136.0866667 97.35333333 0.05249596 -0.499941443 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 544922 544922 'Zkscan4' mRNA 125.11 133.29 161.27 2.84 2.98 3.88 1.92 1.74 2.1 3.233333333 1.92 97.07 85.99 102.98 139.89 95.34666667 0.022507742 -0.578972643 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding" GO:0006357///regulation of transcription by RNA polymerase II 544963 544963 'Iqgap2' mRNA 1270 1349 976 11.69 12.21 9.55 7.64 7.79 8.45 11.15 7.96 955 952 1023 1198.333333 976.6666667 0.005091465 -0.300535344 04810///Regulation of actin cytoskeleton GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005902///microvillus+++GO:0009986///cell surface+++GO:0030027///lamellipodium+++GO:0030175///filopodium "GO:0005096///GTPase activator activity+++GO:0005516///calmodulin binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0031267///small GTPase binding+++GO:0051015///actin filament binding+++GO:0071933///Arp2/3 complex binding" GO:0007165///signal transduction+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0043087///regulation of GTPase activity+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:2000249///regulation of actin cytoskeleton reorganization 544971 544971 'Bdp1' mRNA 1025.26 1001.01 970.9 4.82 4.66 4.77 3.88 3.45 3.92 4.75 3.75 876 764.1 868.04 999.0566667 836.0466667 0.005867417 -0.268947993 GO:0000126///transcription factor TFIIIB complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0001156///TFIIIC-class transcription factor complex binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0070898///RNA polymerase III preinitiation complex assembly" 544998 544998 'Gm16440' mRNA 0 0 1 0 0 0.11 0 0 0 0.036666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545007 545007 'Gm5796' mRNA 1.72 0 0 0.05 0 0 0 0.16 0 0.016666667 0.053333333 0 5.58 0 0.573333333 1.86 0.544188322 2.229773786 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545013 545013 'Gm5797' mRNA 1 1.02 4 0.06 0.06 0.27 0 0.11 0 0.13 0.036666667 0 1.87 0 2.006666667 0.623333333 0.371972633 -2.527226314 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545030 545030 'Wdfy4' mRNA 10 15 8 0.05 0.08 0.05 1.46 1.34 1.25 0.06 1.35 325 293 269 11 295.6666667 3.94E-51 4.738782562 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum "GO:0006914///autophagy+++GO:0019882///antigen processing and presentation+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0098586///cellular response to virus" 545085 545085 'Wdr70' mRNA 754 729 727 24.02 22.91 24.3 29.26 26.31 27.57 23.74333333 27.71333333 1040 906 951 736.6666667 965.6666667 1.12E-04 0.377360979 GO:0005634///nucleus+++GO:0035861///site of double-strand break GO:0019899///enzyme binding GO:1903775///regulation of DNA double-strand break processing+++GO:2001173///regulation of histone H2B conserved C-terminal lysine ubiquitination 545091 545091 'Hnrnpa1l2-ps2' mRNA 40.17 33.16 27.22 2.13 1.74 1.53 0.28 0.33 0.48 1.8 0.363333333 6.08 7.05 10.11 33.51666667 7.746666667 3.33E-04 -2.125686293 03040///Spliceosome+++05014///Amyotrophic lateral sclerosis 545123 545123 'Cyp2d11' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00140///Steroid hormone biosynthesis+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0042738///exogenous drug catabolic process 545124 545124 'Tdg-ps' mRNA 183.03 176.74 190.67 3.42 3.25 3.77 3.24 2.98 2.98 3.48 3.066666667 199.71 179.51 178.14 183.48 185.7866667 0.994852973 0.003833249 03410///Base excision repair 545126 545126 'CN725425' mRNA 10 13 10 0.16 0.21 0.17 0.1 0.1 0.03 0.18 0.076666667 7 7 2 11 5.333333333 0.295470344 -1.054578856 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545136 545136 'Fam186b' mRNA 130 141 83 0.75 0.8 0.51 0.46 0.37 0.32 0.686666667 0.383333333 90 72 62 118 74.66666667 0.023081281 -0.66468547 GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0008150///biological_process 545156 545156 'Kalrn' mRNA 2348.89 2218.4 1955.08 4.01 3.66 3.83 3.21 2.93 2.92 3.833333333 3.02 1370.77 1154.17 1276.9 2174.123333 1267.28 6.03E-23 -0.789543226 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0019898///extrinsic component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding "GO:0001662///behavioral fear response+++GO:0006468///protein phosphorylation+++GO:0007266///Rho protein signal transduction+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0007528///neuromuscular junction development+++GO:0007595///lactation+++GO:0007613///memory+++GO:0008344///adult locomotory behavior+++GO:0009612///response to mechanical stimulus+++GO:0014909///smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0035176///social behavior+++GO:0035556///intracellular signal transduction+++GO:0042711///maternal behavior+++GO:0043547///positive regulation of GTPase activity+++GO:0046959///habituation+++GO:0048148///behavioral response to cocaine+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048659///smooth muscle cell proliferation+++GO:0050773///regulation of dendrite development+++GO:0050790///regulation of catalytic activity+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060125///negative regulation of growth hormone secretion+++GO:0060137///maternal process involved in parturition+++GO:0060999///positive regulation of dendritic spine development+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061368///behavioral response to formalin induced pain+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:0098989///NMDA selective glutamate receptor signaling pathway+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton" 54519 54519 'Apbb1ip' mRNA 36 27 22 0.79 0.58 0.51 4.97 4.76 5.78 0.626666667 5.17 261 244 294 28.33333333 266.3333333 2.09E-38 3.224253136 04015///Rap1 signaling pathway+++04611///Platelet activation GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0042101///T cell receptor complex+++GO:0042995///cell projection GO:0005515///protein binding GO:0002291///T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:0007165///signal transduction+++GO:0045785///positive regulation of cell adhesion 545192 545192 'Baiap3' mRNA 228.12 226.21 187.44 2.51 2.55 2.26 1.51 1.59 1.69 2.44 1.596666667 157.14 161.14 167.05 213.9233333 161.7766667 0.032876518 -0.410425658 05202///Transcriptional misregulation in cancer GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0055038///recycling endosome membrane+++GO:0098793///presynapse+++GO:0098982///GABA-ergic synapse GO:0000149///SNARE binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0019905///syntaxin binding+++GO:0046872///metal ion binding "GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006887///exocytosis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050795///regulation of behavior+++GO:0050804///modulation of chemical synaptic transmission+++GO:1905413///regulation of dense core granule exocytosis+++GO:1990502///dense core granule maturation" 54524 54524 'Syt6' mRNA 54 42 23 0.66 0.49 0.39 0.23 0.24 0.11 0.513333333 0.193333333 21 22 10 39.66666667 17.66666667 0.031952414 -1.166558018 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0070382///exocytic vesicle+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099699///integral component of synaptic membrane GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0048306///calcium-dependent protein binding GO:0007340///acrosome reaction+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0060478///acrosomal vesicle exocytosis+++GO:0071277///cellular response to calcium ion+++GO:0099525///presynaptic dense core vesicle exocytosis 54525 54525 'Syt7' mRNA 79 83 61 0.6 0.67 0.52 0.12 0.15 0.14 0.596666667 0.136666667 17 20 19 74.33333333 18.66666667 1.49E-07 -1.99890611 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030658///transport vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0070382///exocytic vesicle+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0046872///metal ion binding" GO:0001778///plasma membrane repair+++GO:0006887///exocytosis+++GO:0006909///phagocytosis+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0036465///synaptic vesicle recycling+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0046850///regulation of bone remodeling+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0050764///regulation of phagocytosis+++GO:0050796///regulation of insulin secretion+++GO:0070092///regulation of glucagon secretion+++GO:0071277///cellular response to calcium ion+++GO:0090119///vesicle-mediated cholesterol transport+++GO:0090385///phagosome-lysosome fusion+++GO:0099502///calcium-dependent activation of synaptic vesicle fusion+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1990926///short-term synaptic potentiation+++GO:1990927///calcium ion regulated lysosome exocytosis 545253 545253 'Gm5820' mRNA 48 22.01 43 1.07 0.63 0.88 0.63 0.6 0.59 0.86 0.606666667 39 33.01 28.03 37.67 33.34666667 0.748070175 -0.197049345 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54526 54526 'Syt10' mRNA 36 28 17.01 0.71 0.57 0.38 0.14 0.43 0.28 0.553333333 0.283333333 10 19 19 27.00333333 16 0.235600457 -0.751297058 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0070382///exocytic vesicle+++GO:0098793///presynapse "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0007608///sensory perception of smell+++GO:0014059///regulation of dopamine secretion+++GO:0016079///synaptic vesicle exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0071277///cellular response to calcium ion 545260 545260 'Arsi' mRNA 97 77 71 1.94 1.52 1.51 0.23 0.44 0.41 1.656666667 0.36 13 25 23 81.66666667 20.33333333 1.50E-07 -2.010885695 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum GO:0003824///catalytic activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding 545276 545276 'Gal3st3' mRNA 1609.01 1411.65 1380.47 37.12 32.06 33.78 16.01 14.52 14.6 34.32 15.04333333 798.03 707.17 704.6 1467.043333 736.6 4.08E-28 -1.006028844 GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0009247///glycolipid biosynthetic process 545279 545279 'Ms4a15' mRNA 2 6 0 0.07 0.2 0 0.03 0 0.03 0.09 0.02 1 0 1 2.666666667 0.666666667 0.445479962 -1.980747673 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 545291 545291 'Hpse2' mRNA 11 14 13 0.17 0.18 0.23 0.39 0.08 0.09 0.193333333 0.186666667 22 6 8 12.66666667 12 0.917322082 -0.101879807 00531///Glycosaminoglycan degradation+++05205///Proteoglycans in cancer GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0031012///extracellular matrix "GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0043395///heparan sulfate proteoglycan binding" GO:0008284///positive regulation of cell proliferation+++GO:0030198///extracellular matrix organization 545366 545366 'Cfhr2' mRNA 0 0 1.03 0 0 0.04 0.07 0 0.03 0.013333333 0.033333333 2.06 0 1.02 0.343333333 1.026666667 0.73494348 1.452265523 04610///Complement and coagulation cascades GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0001851///complement component C3b binding+++GO:0008201///heparin binding GO:0030449///regulation of complement activation 545370 545370 'Hmcn1' mRNA 372 304 341 1.05 0.84 1.02 0.45 0.43 0.47 0.97 0.45 182 173 186 339 180.3333333 1.77E-08 -0.92409127 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0032154///cleavage furrow+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0007049///cell cycle+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009617///response to bacterium+++GO:0051301///cell division 545384 545384 'Ifi214' mRNA 4.55 4.42 0 0.21 0.2 0 1.02 0.71 0.74 0.136666667 0.823333333 25.13 17.03 17.5 2.99 19.88666667 0.001508739 2.885154561 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0035458///cellular response to interferon-beta 545389 545389 'Cep170' mRNA 883.25 851.88 714.14 4.33 4 3.61 4.42 4.6 5.42 3.98 4.813333333 888.42 833.43 976.58 816.4233333 899.4766667 0.268432748 0.131255412 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0072686///mitotic spindle+++GO:0120103///centriolar subdistal appendage GO:0005515///protein binding GO:0008150///biological_process 545391 545391 'Catspere2' mRNA 473.61 479.46 272.52 4.17 4.17 2.26 0.61 1.08 1.04 3.533333333 0.91 108 136.47 162.33 408.53 135.6 4.96E-14 -1.589872507 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036128///CatSper complex+++GO:0097228///sperm principal piece GO:0003674///molecular_function GO:0008150///biological_process 545428 545428 'Ccdc141' mRNA 781 831 719 8.51 7.94 8.58 6.29 6.31 7.01 8.343333333 6.536666667 733 693 774 777 733.3333333 0.437367656 -0.093404099 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0005515///protein binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0051642///centrosome localization+++GO:0070593///dendrite self-avoidance 545471 545471 'Zfp345' mRNA 0 3.27 6.02 0 0.07 0.13 0 0.04 0.18 0.066666667 0.073333333 0 2.02 10.05 3.096666667 4.023333333 0.863090843 0.382193193 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 545474 545474 'Scrt2' mRNA 2 1 2 0.03 0.02 0.03 0 0.01 0 0.026666667 0.003333333 0 1 0 1.666666667 0.333333333 0.459799792 -2.23882682 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:2001222///regulation of neuron migration" 545477 545477 'Bpifa6' mRNA 29 24 20 1.19 0.94 0.91 0.03 0.09 0.13 1.013333333 0.083333333 1 2 3 24.33333333 2 3.87E-05 -3.60975318 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0008150///biological_process 545481 545481 'Arhgap40' mRNA 0 2 1 0 0.06 0.03 0.05 0.05 0.1 0.03 0.066666667 2 2 4 1 2.666666667 0.537758749 1.409109602 GO:0005737///cytoplasm GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0030833///regulation of actin filament polymerization+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction 545486 545486 'Tubb1' mRNA 5 10 2 0.14 0.28 0.06 0.1 0.18 0.05 0.16 0.11 4 7 2 5.666666667 4.333333333 0.81594209 -0.372457379 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0051225///spindle assembly 545490 545490 'Zfp973' mRNA 35.03 44.33 23.2 1.58 1.97 1.11 1.22 1.16 1.26 1.553333333 1.213333333 30.93 28.79 30.97 34.18666667 30.23 0.720293678 -0.214877734 GO:0005575///cellular_component+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 545527 545527 'Erich6' mRNA 2 4 6 0.05 0.1 0.2 0.2 0 0.04 0.116666667 0.08 7 0 1 4 2.666666667 0.750319743 -0.634304629 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545531 545531 'Gm5848' mRNA 19 14 13 0.23 0.17 0.17 0.06 0.02 0.04 0.19 0.04 6 2 4 15.33333333 4 0.026973076 -1.952507746 545554 545554 'Ankrd34a' mRNA 56 75 61 1.17 1.5 1.37 0.95 1.02 1.16 1.346666667 1.043333333 51 55 61 64 55.66666667 0.605362619 -0.210426051 GO:0003674///molecular_function GO:0008150///biological_process 54561 54561 'Nap1l3' mRNA 205 271 195 4 5.21 4.04 1.99 2.08 1.65 4.416666667 1.906666667 117 120 94 223.6666667 110.3333333 1.01E-06 -1.026857255 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly 545611 545611 'Fam205a2' mRNA 18.05 25.99 14.64 0.2 0.32 0.2 0.11 0 0.07 0.24 0.06 10.34 0 6.86 19.56 5.733333333 0.038628159 -1.847013537 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 54562 54562 'Lrrc6' mRNA 204 211 207 5.55 5.65 5.97 0.4 0.63 0.56 5.723333333 0.53 17 26 23 207.3333333 22 5.93E-32 -3.247171067 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0090651///apical cytoplasm GO:0005515///protein binding GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0008584///male gonad development+++GO:0030317///flagellated sperm motility+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0043393///regulation of protein binding+++GO:0044458///motile cilium assembly+++GO:0051649///establishment of localization in cell+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0061458///reproductive system development+++GO:0061512///protein localization to cilium+++GO:0070286///axonemal dynein complex assembly+++GO:0090660///cerebrospinal fluid circulation 545622 545622 'Ptpn3' mRNA 1094 1100 752 9.34 9.23 6.72 2.32 1.95 2.01 8.43 2.093333333 310 256 261 982 275.6666667 1.34E-42 -1.838256016 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane GO:0001784///phosphotyrosine residue binding+++GO:0004713///protein tyrosine kinase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016301///kinase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017080///sodium channel regulator activity+++GO:0051117///ATPase binding GO:0006470///protein dephosphorylation+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0097421///liver regeneration+++GO:0098902///regulation of membrane depolarization during action potential+++GO:2000649///regulation of sodium ion transmembrane transporter activity 54563 54563 'Nup210' mRNA 595 508 551 4.45 3.74 4.36 2.16 2.19 1.97 4.183333333 2.106666667 332 329 293 551.3333333 318 1.07E-09 -0.807065398 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0065003///protein-containing complex assembly 545645 545645 'Gm13283' mRNA 1.04 1.17 1.1 0.09 0.1 0.1 0 0 0 0.096666667 0 0 0 0 1.103333333 0 0.568344116 -2.455252046 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 545649 545649 'Gm13276' mRNA 27.02 12.95 18.93 1.1 0.52 0.82 1.69 1.95 1.07 0.813333333 1.57 47.73 53.88 29.43 19.63333333 43.68 0.022938108 1.165968329 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 545650 545650 'Gm13277' mRNA 6.1 0 0 0.25 0 0 0 0 0 0.083333333 0 0 0 0 2.033333333 0 0.3586977 -3.42755115 GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 545651 545651 'Gm13278' mRNA 50.91 69.01 48.79 2.07 2.76 2.1 1.65 1.8 2.81 2.31 2.086666667 46.74 49.72 77.01 56.23666667 57.82333333 0.938641229 0.037076099 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0008150///biological_process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 545652 545652 'Gm13275' mRNA 57.6 63.38 56.64 2.18 2.36 2.27 2.36 1.65 1.46 2.27 1.823333333 71.69 49.1 42.96 59.20666667 54.58333333 0.772074606 -0.133904014 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006952///defense response+++GO:0006959///humoral immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 545662 545662 'Pramel17' mRNA 0 1.1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.366666667 0 0.863090843 -0.97353728 GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 545677 545677 'Gm12888' mRNA 0 1 0 0 0.05 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545725 545725 'Mterf1a' mRNA 63.4 50.96 94.08 2.6 2.07 4.07 2.93 3.19 2.75 2.913333333 2.956666667 77.59 83.01 70.16 69.48 76.92 0.775375801 0.127849576 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding "GO:0006353///DNA-templated transcription, termination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006393///termination of mitochondrial transcription+++GO:0032392///DNA geometric change" 545728 545728 'Gm5861' mRNA 2.73 6.87 5.63 0.15 0.36 0.32 0.23 0.34 0 0.276666667 0.19 5 7 0 5.076666667 4 0.942313116 -0.129066183 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545732 545732 '4933402N22Rik' mRNA 11.94 3.64 1.45 0.67 0.2 0.09 0 0.15 0.3 0.32 0.15 0 3 5.82 5.676666667 2.94 0.629613215 -0.885778401 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545739 545739 'Gm5862' mRNA 7.68 6.19 6.69 0.65 0.52 0.6 0 0 0 0.59 0 0 0 0 6.853333333 0 0.005769418 -5.116869926 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 545812 545812 'Pilrb2' mRNA 3 4 5 0.19 0.24 0.33 5.78 7.25 5.95 0.253333333 6.326666667 113 137.4 112.24 4 120.88 1.09E-21 4.903999843 05168///Herpes simplex virus 1 infection GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042288///MHC class I protein binding 545814 545814 'Smok3a' mRNA 5.41 8.33 16.11 0.11 0.17 0.35 0.1 0.18 0.04 0.21 0.106666667 5.77 8.83 2.26 9.95 5.62 0.387110469 -0.981554565 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 545817 545817 'Cyp2w1' mRNA 7 7 3 0.1 0.1 0.05 0 0.01 0 0.083333333 0.003333333 0 1 0 5.666666667 0.333333333 0.037489929 -3.979461018 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0001972///retinoic acid binding+++GO:0004497///monooxygenase activity+++GO:0005503///all-trans retinal binding+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:1904768///all-trans-retinol binding" GO:0006082///organic acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0034653///retinoic acid catabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0046222///aflatoxin metabolic process 545893 545893 'Mansc4' mRNA 795 801 810 44.07 43.88 47.65 16.09 19.38 18.59 45.2 18.02 333 391 372 802 365.3333333 1.12E-22 -1.145947885 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 545902 545902 'Ptprh' mRNA 1 1 2 0.01 0.01 0.03 0 0.02 0.01 0.016666667 0.01 0 2 1 1.333333333 1 0.879214745 -0.428377116 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0045296///cadherin binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 545938 545938 'Zfp607a' mRNA 155.6 121.92 152.79 2.77 2.21 2.84 2.02 1.47 2.15 2.606666667 1.88 140.45 99 141.53 143.4366667 126.9933333 0.515719367 -0.189031023 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 545975 545975 'Cers3' mRNA 5 0 8 0.08 0 0.14 0.16 0.1 0.2 0.073333333 0.153333333 11 7 13 4.333333333 10.33333333 0.305235131 1.212531404 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008544///epidermis development+++GO:0030148///sphingolipid biosynthetic process+++GO:0030216///keratinocyte differentiation+++GO:0046513///ceramide biosynthetic process+++GO:0070268///cornification 54598 54598 'Calcrl' mRNA 264 309 260 3 3.41 3.12 4.87 3.68 3.47 3.176666667 4.006666667 498 367 344 277.6666667 403 0.001667008 0.524382727 04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1903143///adrenomedullin receptor complex+++GO:1990406///CGRP receptor complex GO:0001605///adrenomedullin receptor activity+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004948///calcitonin receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:1990409///adrenomedullin binding GO:0001525///angiogenesis+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation+++GO:0015031///protein transport+++GO:0031623///receptor internalization+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0071329///cellular response to sucrose stimulus+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway+++GO:1990410///adrenomedullin receptor signaling pathway 54601 54601 'Foxo4' mRNA 126 121 65 2.18 2.07 1.19 1.32 1.1 1.27 1.813333333 1.23 87 70 81 104 79.33333333 0.233049608 -0.392138678 04014///Ras signaling pathway+++04068///FoxO signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:1990841///promoter-specific chromatin binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007568///aging+++GO:0008285///negative regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0031667///response to nutrient levels+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0071158///positive regulation of cell cycle arrest+++GO:1990785///response to water-immersion restraint stress" 546024 546024 'Crxos' mRNA 14 13 7 0.37 0.65 0.31 0.07 0.05 0.24 0.443333333 0.12 3 2 6 11.33333333 3.666666667 0.111841816 -1.628149613 GO:0005634///nucleus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding "GO:0001835///blastocyst hatching+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048666///neuron development" 54604 54604 'Pcnx' mRNA 685 845 708 3.51 4.46 4.06 3.74 3.62 4.09 4.01 3.816666667 691 631 733 746 685 0.306640046 -0.133583874 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 546049 546049 'Rps23rg1' mRNA 144.13 156.44 143.1 5.2 5.56 5.47 0.62 0.64 1.05 5.41 0.77 19.7 19.84 32.45 147.89 23.99666667 1.76E-18 -2.672422044 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane GO:0008179///adenylate cyclase binding GO:0001933///negative regulation of protein phosphorylation+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0050435///amyloid-beta metabolic process+++GO:1902430///negative regulation of amyloid-beta formation 546055 546055 'Adam39' mRNA 1.52 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.506666667 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990913///sperm head plasma membrane GO:0003674///molecular_function+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity GO:0006508///proteolysis+++GO:0008584///male gonad development 54607 54607 'Socs6' mRNA 2056 1975 1637 18.05 17.06 15.43 11.1 11.14 11.7 16.84666667 11.31333333 1459 1429 1486 1889.333333 1458 2.99E-06 -0.381809861 04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0001772///immunological synapse+++GO:0005829///cytosol+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0001678///cellular glucose homeostasis+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0009968///negative regulation of signal transduction+++GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0050868///negative regulation of T cell activation 546071 546071 'Mast3' mRNA 1109 1150 879 10.46 10.87 8.93 10.23 8.39 9.88 10.08666667 9.5 1225 989 1153 1046 1122.333333 0.458430985 0.09317958 GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 54608 54608 'Abhd2' mRNA 2559 2254 2247 20.34 17.94 18.84 25.19 20.24 28.15 19.04 24.52666667 3438 2825 3452 2353.333333 3238.333333 1.21E-07 0.447722656 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0036126///sperm flagellum+++GO:0097524///sperm plasma membrane GO:0003707///steroid hormone receptor activity+++GO:0004806///triglyceride lipase activity+++GO:0008126///acetylesterase activity+++GO:0016787///hydrolase activity+++GO:0033878///hormone-sensitive lipase activity+++GO:0034338///short-chain carboxylesterase activity+++GO:0042562///hormone binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0007340///acrosome reaction+++GO:0009611///response to wounding+++GO:0016042///lipid catabolic process+++GO:0030336///negative regulation of cell migration+++GO:0032570///response to progesterone+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0044255///cellular lipid metabolic process+++GO:0046464///acylglycerol catabolic process+++GO:0048240///sperm capacitation+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0051793///medium-chain fatty acid catabolic process 54609 54609 'Ubqln2' mRNA 1078 1137 372 17.65 18.32 6.46 6.43 7.58 8.1 14.14333333 7.37 452 520 551 862.3333333 507.6666667 0.155437375 -0.751797807 04141///Protein processing in endoplasmic reticulum+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding GO:0000045///autophagosome assembly+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0016241///regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1904021///negative regulation of G protein-coupled receptor internalization+++GO:2000785///regulation of autophagosome assembly 54610 54610 'Tbc1d8' mRNA 481.32 424.21 489.42 6.22 5.45 6.62 4.11 4.24 4.41 6.096666667 4.253333333 365.24 373.32 381.52 464.9833333 373.36 0.020338466 -0.331250773 GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 54611 54611 'Pde3a' mRNA 95 85.03 102.11 0.46 0.4 0.52 0.38 0.41 0.38 0.46 0.39 91.03 96 88 94.04666667 91.67666667 0.8778755 -0.051078585 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04924///Renin secretion+++05032///Morphine addiction GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" GO:0001556///oocyte maturation+++GO:0007165///signal transduction+++GO:0009410///response to xenobiotic stimulus+++GO:0019933///cAMP-mediated signaling+++GO:0019934///cGMP-mediated signaling+++GO:0040020///regulation of meiotic nuclear division+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043116///negative regulation of vascular permeability+++GO:0043117///positive regulation of vascular permeability+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0060282///positive regulation of oocyte development+++GO:0071321///cellular response to cGMP+++GO:0071560///cellular response to transforming growth factor beta stimulus 54612 54612 'Sfrp5' mRNA 1381 1458 1126 41.62 43.3 36 12.09 13.19 13.25 40.30666667 12.84333333 461 491 489 1321.666667 480.3333333 5.80E-48 -1.466722045 04310///Wnt signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0017147///Wnt-protein binding GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030510///regulation of BMP signaling pathway+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043508///negative regulation of JUN kinase activity+++GO:0048546///digestive tract morphogenesis+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060028///convergent extension involved in axis elongation+++GO:0060070///canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090175///regulation of establishment of planar polarity+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:2000041///negative regulation of planar cell polarity pathway involved in axis elongation+++GO:2000057///negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis 54613 54613 'St3gal6' mRNA 968 1112 924 22.33 24.65 22.3 17.34 15.77 16.32 23.09333333 16.47666667 873 788 802 1001.333333 821 0.002558664 -0.296711976 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0052798///beta-galactoside alpha-2,3-sialyltransferase activity" GO:0006464///cellular protein modification process+++GO:0006486///protein glycosylation+++GO:0006664///glycolipid metabolic process+++GO:0009311///oligosaccharide metabolic process+++GO:0071354///cellular response to interleukin-6+++GO:0097503///sialylation 546134 546134 'Gramd2' mRNA 1109 1253 1217 15.4 17.15 18.16 7.58 7.31 7.95 16.90333333 7.613333333 616 570 628 1193 604.6666667 7.57E-24 -0.993686764 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0044232///organelle membrane contact site "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding" GO:0061817///endoplasmic reticulum-plasma membrane tethering+++GO:2001256///regulation of store-operated calcium entry 54614 54614 'Prpf40b' mRNA 1228 1220 1097 20.47 20.11 19.48 12.7 10.8 12.67 20.02 12.05666667 876 727 850 1181.666667 817.6666667 6.15E-09 -0.542560374 03040///Spliceosome GO:0005634///nucleus+++GO:0005685///U1 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome" 546143 546143 'Ccpg1os' mRNA 324 340 315 32.48 33.94 34.74 15.52 17.68 16.95 33.72 16.71666667 177 195 180 326.3333333 184 1.10E-07 -0.837083622 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 546144 546144 'Wdr72' mRNA 64 66 43 0.65 0.66 0.46 0.46 0.49 0.43 0.59 0.46 52 54 47 57.66666667 51 0.684464855 -0.181415271 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0022617///extracellular matrix disassembly+++GO:0031214///biomineral tissue development+++GO:0070166///enamel mineralization+++GO:0072659///protein localization to plasma membrane 54615 54615 'Npff' mRNA 28 26 19 5.77 5.38 4.16 4.55 3 4.17 5.103333333 3.906666667 25 16 22 24.33333333 21 0.750011424 -0.221308952 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0098794///postsynapse GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0005184///neuropeptide hormone activity GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0003254///regulation of membrane depolarization+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0010459///negative regulation of heart rate+++GO:0021510///spinal cord development+++GO:0030103///vasopressin secretion+++GO:0032099///negative regulation of appetite+++GO:0042493///response to drug+++GO:0043278///response to morphine+++GO:0045777///positive regulation of blood pressure+++GO:0046676///negative regulation of insulin secretion+++GO:0051930///regulation of sensory perception of pain+++GO:0060079///excitatory postsynaptic potential+++GO:0060135///maternal process involved in female pregnancy+++GO:0070253///somatostatin secretion 54616 54616 'Extl3' mRNA 936 955 906 8.35 8.41 8.58 9.69 9.12 8.18 8.446666667 8.996666667 1249 1152 1024 932.3333333 1141.666667 0.004556925 0.27982517 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001888///glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030307///positive regulation of cell growth 546161 546161 'Fbxw18' mRNA 1 0 0 0.04 0 0 0.03 0.07 0.17 0.013333333 0.09 1 2 5 0.333333333 2.666666667 0.254496157 2.890362185 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54624 54624 'Paf1' mRNA 1828.72 1839.15 1791.85 50.6 50.66 53.06 38.8 37.93 39.8 51.44 38.84333333 1594.68 1542.48 1592.33 1819.906667 1576.496667 0.003894882 -0.219231255 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016593///Cdc73/Paf1 complex+++GO:0030054///cell junction+++GO:0035327///transcriptionally active chromatin GO:0000993///RNA polymerase II complex binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001711///endodermal cell fate commitment+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006378///mRNA polyadenylation+++GO:0010390///histone monoubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0016570///histone modification+++GO:0016584///nucleosome positioning+++GO:0019827///stem cell population maintenance+++GO:0031062///positive regulation of histone methylation+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0033523///histone H2B ubiquitination+++GO:0034504///protein localization to nucleus+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0071222///cellular response to lipopolysaccharide+++GO:1902808///positive regulation of cell cycle G1/S phase transition 546250 546250 'Gm5930' mRNA 1 0 0 0.03 0 0 0.03 0.06 0.03 0.01 0.04 1 2 1 0.333333333 1.333333333 0.578380446 1.889799319 GO:0016020///membrane+++GO:0016021///integral component of membrane 54630 54630 'Prickle3' mRNA 228.6 223.31 224.24 5.27 5.03 5.46 4.2 4.63 3.61 5.253333333 4.146666667 209.8 225.9 175.24 225.3833333 203.6466667 0.457835686 -0.160432961 04310///Wnt signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0030030///cell projection organization 54631 54631 'Nphs1' mRNA 18.9 28.96 21.27 0.17 0.27 0.21 0.17 0.12 0.11 0.216666667 0.133333333 21.24 14.46 12.97 23.04333333 16.22333333 0.440785641 -0.524512087 GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0042995///cell projection+++GO:0045121///membrane raft GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0019904///protein domain specific binding+++GO:0030507///spectrin binding+++GO:0050839///cell adhesion molecule binding+++GO:0051393///alpha-actinin binding GO:0000165///MAPK cascade+++GO:0007155///cell adhesion+++GO:0007254///JNK cascade+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0007520///myoblast fusion+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032836///glomerular basement membrane development+++GO:0035418///protein localization to synapse+++GO:0044062///regulation of excretion+++GO:0072015///glomerular visceral epithelial cell development+++GO:0098609///cell-cell adhesion 54632 54632 'Ftsj1' mRNA 762 758 719 12.13 11.87 12.15 7.53 8.94 8.23 12.05 8.233333333 544 631 576 746.3333333 583.6666667 0.001244873 -0.36466418 GO:0005737///cytoplasm GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0009020///tRNA (guanosine-2'-O-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0052666///tRNA (cytosine-2'-O-)-methyltransferase activity GO:0001510///RNA methylation+++GO:0002128///tRNA nucleoside ribose methylation+++GO:0002181///cytoplasmic translation+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 546325 546325 'Gm5936' mRNA 1.02 1.06 3.59 0.02 0.02 0.07 0.25 0 0 0.036666667 0.083333333 15 0 0 1.89 5 0.476530636 1.518375215 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54633 54633 'Pqbp1' mRNA 1393 1378 1321 78.26 76.38 78.41 64.53 63.79 65.51 77.68333333 64.61 1324 1286 1310 1364 1306.666667 0.434782282 -0.07350678 03040///Spliceosome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0010494///cytoplasmic stress granule+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0097546///ciliary base GO:0003690///double-stranded DNA binding+++GO:0008022///protein C-terminus binding+++GO:0043021///ribonucleoprotein complex binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031175///neuron projection development+++GO:0032481///positive regulation of type I interferon production+++GO:0034063///stress granule assembly+++GO:0043484///regulation of RNA splicing+++GO:0045087///innate immune response+++GO:0048814///regulation of dendrite morphogenesis+++GO:0051607///defense response to virus+++GO:0071360///cellular response to exogenous dsRNA+++GO:1902857///positive regulation of non-motile cilium assembly" 546336 546336 'Prrg1' mRNA 134 126 144 1.94 1.77 2.24 1.15 0.92 1.3 1.983333333 1.123333333 92 72 101 134.6666667 88.33333333 0.014720914 -0.62442277 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 54634 54634 'Magix' mRNA 190 208 125 3.74 4.03 2.61 2.31 2.4 1.45 3.46 2.053333333 135 137 82 174.3333333 118 0.034954734 -0.566019105 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54635 54635 'Pdgfc' mRNA 1011 1055 834 15.57 15.99 13.64 6.3 5.99 7.65 15.06666667 6.646666667 472 438 553 966.6666667 487.6666667 3.57E-18 -0.994700828 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04810///Regulation of actin cytoskeleton+++05215///Prostate cancer+++05218///Melanoma+++05231///Choline metabolism in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane GO:0005161///platelet-derived growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0042803///protein homodimerization activity+++GO:0070851///growth factor receptor binding GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030335///positive regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048565///digestive tract development+++GO:0048568///embryonic organ development+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0051781///positive regulation of cell division+++GO:0060348///bone development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071230///cellular response to amino acid stimulus+++GO:0120162///positive regulation of cold-induced thermogenesis 54636 54636 'Wdr45' mRNA 1101 996 945 39.38 35.25 36.27 27.7 24.83 25.96 36.96666667 26.16333333 881 762 784 1014 809 6.41E-04 -0.337525549 GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0034045///phagophore assembly site membrane "GO:0008289///lipid binding+++GO:0019901///protein kinase binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1901981///phosphatidylinositol phosphate binding" GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0034497///protein localization to phagophore assembly site+++GO:0044804///autophagy of nucleus 54637 54637 'Praf2' mRNA 885 882 890 45.03 44.31 48.04 50.8 56.77 51.72 45.79333333 53.09666667 1146 1249 1128 885.6666667 1174.333333 3.69E-05 0.395156577 GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0015031///protein transport 54638 54638 'Ccdc22' mRNA 603 560.85 614.78 15.03 13.77 16.26 15.67 17.16 16.43 15.02 16.42 722.86 772.87 733.82 592.8766667 743.1833333 0.007336633 0.312499202 GO:0000164///protein phosphatase type 1 complex+++GO:0005575///cellular_component+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019903///protein phosphatase binding+++GO:0097602///cullin family protein binding+++GO:2001069///glycogen binding GO:0005979///regulation of glycogen biosynthetic process+++GO:0006878///cellular copper ion homeostasis+++GO:0006893///Golgi to plasma membrane transport+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0008150///biological_process+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042632///cholesterol homeostasis+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:2000465///regulation of glycogen (starch) synthase activity 54644 54644 'Otud5' mRNA 747 724 502 10.34 10.04 7.36 8.34 8.12 9.04 9.246666667 8.5 694 649 735 657.6666667 692.6666667 0.68308755 0.07025294 04622///RIG-I-like receptor signaling pathway GO:0005575///cellular_component GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity "GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability+++GO:0032496///response to lipopolysaccharide+++GO:0032625///interleukin-21 production+++GO:0032638///interleukin-9 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043374///CD8-positive, alpha-beta T cell differentiation+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904263///positive regulation of TORC1 signaling+++GO:1904515///positive regulation of TORC2 signaling+++GO:2000316///regulation of T-helper 17 type immune response" 54645 54645 'Gripap1' mRNA 929 948 994 16.35 16.67 18.59 17.23 16.06 16.87 17.20333333 16.72 1108 1012 1063 957 1061 0.206956199 0.134478999 GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane+++GO:0098837///postsynaptic recycling endosome+++GO:0098978///glutamatergic synapse+++GO:0098998///extrinsic component of postsynaptic early endosome membrane GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0015031///protein transport+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099158///regulation of recycling endosome localization within postsynapse+++GO:1905244///regulation of modification of synaptic structure" 54646 54646 'Ppp1r3f' mRNA 136 131 110 2.12 2.01 1.82 0.91 0.71 0.71 1.983333333 0.776666667 67 51 51 125.6666667 56.33333333 1.13E-05 -1.168067519 04910///Insulin signaling pathway GO:0000164///protein phosphatase type 1 complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008157///protein phosphatase 1 binding+++GO:0019903///protein phosphatase binding+++GO:2001069///glycogen binding GO:0005979///regulation of glycogen biosynthetic process+++GO:2000465///regulation of glycogen (starch) synthase activity 54648 54648 'Ccdc120' mRNA 559 544 534 8.33 7.97 8.44 5.05 5.42 5.28 8.246666667 5.25 390 409 395 545.6666667 398 1.19E-04 -0.466620585 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0120103///centriolar subdistal appendage GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0008104///protein localization+++GO:0034454///microtubule anchoring at centrosome 54650 54650 'Sfmbt1' mRNA 543 533 447 3.64 3.49 3.16 3.56 3.03 3.56 3.43 3.383333333 616 510 595 507.6666667 573.6666667 0.218852675 0.166439699 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0042393///histone binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048635///negative regulation of muscle organ development" 54651 54651 'Usp27x' mRNA 13 10 10 0.22 0.17 0.18 0.29 0.21 0.23 0.19 0.243333333 20 14 15 11 16.33333333 0.482020442 0.557010663 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0043065///positive regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination 54652 54652 'Cacna1f' mRNA 1 0 2 0.01 0 0.02 0.24 0.23 0.15 0.01 0.206666667 31 29 19 1 26.33333333 1.29E-05 4.697938637 "04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04723///Retrograde endocannabinoid signaling+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05207///Chemical carcinogenesis - receptor activation+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy" GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0008331///high voltage-gated calcium channel activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007409///axonogenesis+++GO:0007601///visual perception+++GO:0034765///regulation of ion transmembrane transport+++GO:0048813///dendrite morphogenesis+++GO:0050896///response to stimulus+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0055085///transmembrane transport+++GO:0060041///retina development in camera-type eye+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:1901386///negative regulation of voltage-gated calcium channel activity 546611 546611 'Klhl33' mRNA 213.93 186.28 199.08 1.99 1.66 1.94 1.84 1.31 1.26 1.863333333 1.47 229.57 162.01 152.15 199.7633333 181.2433333 0.538593357 -0.155371254 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 546623 546623 'Gm5958' mRNA 0 1 1 0 0.09 0.09 0 0.08 0 0.06 0.026666667 0 1 0 0.666666667 0.333333333 0.861179337 -0.920394634 546643 546643 'Ly6a2' mRNA 3 7 4 0.24 0.55 0.33 4.28 2.55 3.57 0.373333333 3.466666667 63 36 51 4.666666667 50 1.25E-08 3.408761188 546644 546644 'Ly6g' mRNA 2 1 4 0.15 0.08 0.32 0.67 0.75 0.58 0.183333333 0.666666667 10 11 9 2.333333333 10 0.067303262 2.072588461 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane 546648 546648 'Klhdc7b' mRNA 699 659.79 520.96 6.44 5.98 5.09 1.45 1.09 1.14 5.836666667 1.226666667 181 133.16 137.72 626.5833333 150.6266667 4.52E-42 -2.066974629 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 54667 54667 'Atp8b2' mRNA 217 94 362 2.13 0.89 3.74 4.4 2.01 3.59 2.253333333 3.333333333 514 231 408 224.3333333 384.3333333 0.351018249 0.730330765 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0007030///Golgi organization+++GO:0015914///phospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation 54670 54670 'Atp8b1' mRNA 331 312 256 2.83 2.6 2.23 1.18 1.29 1.08 2.553333333 1.183333333 165 177 147 299.6666667 163 2.94E-07 -0.885921324 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016604///nuclear body+++GO:0031526///brush border membrane+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:1990531///phospholipid-translocating ATPase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0015247///aminophospholipid transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:1901612///cardiolipin binding "GO:0006855///drug transmembrane transport+++GO:0006869///lipid transport+++GO:0007030///Golgi organization+++GO:0007605///sensory perception of sound+++GO:0008206///bile acid metabolic process+++GO:0015711///organic anion transport+++GO:0015721///bile acid and bile salt transport+++GO:0015914///phospholipid transport+++GO:0015917///aminophospholipid transport+++GO:0021650///vestibulocochlear nerve formation+++GO:0032534///regulation of microvillus assembly+++GO:0034204///lipid translocation+++GO:0045176///apical protein localization+++GO:0045332///phospholipid translocation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060119///inner ear receptor cell development+++GO:1903729///regulation of plasma membrane organization+++GO:2001225///regulation of chloride transport" 54672 54672 'Adgrg3' mRNA 22 20 20 0.34 0.36 0.39 0.95 0.97 1.09 0.363333333 1.003333333 56 54 57 20.66666667 55.66666667 5.00E-04 1.418029237 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0030334///regulation of cell migration+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 546726 546726 'Cyp26c1' mRNA 0 1 0 0 0.04 0 0.03 0 0 0.013333333 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 00830///Retinol metabolism "GO:0001972///retinoic acid binding+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0007417///central nervous system development+++GO:0009952///anterior/posterior pattern specification+++GO:0014032///neural crest cell development+++GO:0016125///sterol metabolic process+++GO:0034653///retinoic acid catabolic process+++GO:0048284///organelle fusion 546729 546729 'Calhm1' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04742///Taste transduction GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005227///calcium activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0015867///ATP transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0050913///sensory perception of bitter taste+++GO:0050916///sensory perception of sweet taste+++GO:0050917///sensory perception of umami taste+++GO:0051260///protein homooligomerization+++GO:0051291///protein heterooligomerization+++GO:0070588///calcium ion transmembrane transport+++GO:0098655///cation transmembrane transport 54673 54673 'Sh3glb1' mRNA 1063 1213 944 14.45 16.88 14.08 38.05 38.58 40.54 15.13666667 39.05666667 3010 2872 2988 1073.333333 2956.666667 7.04E-82 1.453520748 04140///Autophagy - animal+++04144///Endocytosis GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0005504///fatty acid binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006654///phosphatidic acid biosynthetic process+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0008654///phospholipid biosynthetic process+++GO:0010508///positive regulation of autophagy+++GO:0031334///positive regulation of protein complex assembly+++GO:0032465///regulation of cytokinesis+++GO:0032801///receptor catabolic process+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0048102///autophagic cell death+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051084///'de novo' posttranslational protein folding+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0061024///membrane organization+++GO:0090148///membrane fission+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1903527///positive regulation of membrane tubulation+++GO:1903778///protein localization to vacuolar membrane+++GO:1903861///positive regulation of dendrite extension+++GO:2000641///regulation of early endosome to late endosome transport+++GO:2000786///positive regulation of autophagosome assembly 546752 546752 'Gm5977' mRNA 160.39 156.08 154.29 1.51 1.45 1.55 0.54 0.62 0.56 1.503333333 0.573333333 65.92 74.3 65.75 156.92 68.65666667 2.30E-07 -1.215236626 54678 54678 'Zfp108' mRNA 238.01 218.51 214.98 5.06 4.55 4.86 2.12 2.21 2.04 4.823333333 2.123333333 116 117.01 108.46 223.8333333 113.8233333 2.63E-07 -0.985714167 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 546801 546801 'Etv3l' mRNA 0.9 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.3 0 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated" 54683 54683 'Prdx5' mRNA 4504.69 4545.61 4358.33 215.31 214.49 221.02 300.65 316.82 317.53 216.94 311.6666667 7220.79 7421.84 7375.02 4469.543333 7339.216667 8.61E-37 0.704310187 04146///Peroxisome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0001016///RNA polymerase III regulatory region DNA binding+++GO:0003824///catalytic activity+++GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004623///phospholipase A2 activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0051920///peroxiredoxin activity+++GO:0072541///peroxynitrite reductase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" "GO:0000302///response to reactive oxygen species+++GO:0006629///lipid metabolic process+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0016042///lipid catabolic process+++GO:0016480///negative regulation of transcription by RNA polymerase III+++GO:0032060///bleb assembly+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0034599///cellular response to oxidative stress+++GO:0034614///cellular response to reactive oxygen species+++GO:0042744///hydrogen peroxide catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045454///cell redox homeostasis+++GO:0046475///glycerophospholipid catabolic process+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0060785///regulation of apoptosis involved in tissue homeostasis+++GO:0070995///NADPH oxidation+++GO:0098869///cellular oxidant detoxification+++GO:2001057///reactive nitrogen species metabolic process" 546840 546840 'Ldlrad1' mRNA 43.11 53.18 50.44 0.4 0.46 0.47 0.41 0.4 0.47 0.443333333 0.426666667 57.67 50.94 67.04 48.91 58.55 0.572810192 0.240202701 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 546849 546849 'AAdacl4fm3' mRNA 15 14 4 0.84 0.93 0.3 0.19 0.7 0.13 0.69 0.34 5 12 2 11 6.333333333 0.490528396 -0.781159129 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity 546886 546886 'Cfap73' mRNA 45 56 38 3.19 3.93 2.86 0.19 0.06 0.19 3.326666667 0.146666667 3 1 3 46.33333333 2.333333333 2.74E-09 -4.319012175 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097545///axonemal outer doublet GO:0003674///molecular_function+++GO:0070840///dynein complex binding GO:0003341///cilium movement+++GO:0008150///biological_process+++GO:0036159///inner dynein arm assembly+++GO:2000574///regulation of microtubule motor activity 546896 546896 'Olfr455' mRNA 11 10 9 0.75 0.67 0.65 0 0 0 0.69 0 0 0 0 10 0 4.14E-04 -5.773976157 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 54698 54698 'Crtam' mRNA 21 23 12 0.62 0.67 0.38 0.15 0.21 0.16 0.556666667 0.173333333 6 8 6 18.66666667 6.666666667 0.04962137 -1.484095262 GO:0001772///immunological synapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0001768///establishment of T cell polarity+++GO:0001819///positive regulation of cytokine production+++GO:0002250///adaptive immune response+++GO:0002355///detection of tumor cell+++GO:0002376///immune system process+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0008037///cell recognition+++GO:0032729///positive regulation of interferon-gamma production+++GO:0045580///regulation of T cell differentiation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0050863///regulation of T cell activation+++GO:0051606///detection of stimulus+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:2001185///regulation of CD8-positive, alpha-beta T cell activation" 54709 54709 'Eif3i' mRNA 1878 1895 1757 105.71 105.4 104.94 120.71 120.53 122.48 105.35 121.24 2460 2395 2413 1843.333333 2422.666667 5.55E-09 0.383300445 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation 547097 547097 'B020011L13Rik' mRNA 2 5 1 0.04 0.1 0.02 0 0 0 0.053333333 0 0 0 0 2.666666667 0 0.148121942 -3.844293871 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 54710 54710 'Hs3st3b1' mRNA 414.77 523.14 409.69 4.32 5.39 4.52 1.18 0.94 1.11 4.743333333 1.076666667 126.88 99.52 117.48 449.2 114.6266667 5.76E-33 -1.986699119 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity GO:0006477///protein sulfation 547109 547109 'Trim43a' mRNA 5 8.76 3 0.14 0.25 0.09 0.17 0.09 0.08 0.16 0.113333333 7.01 3.51 2.99 5.586666667 4.503333333 0.789197277 -0.420661712 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 54711 54711 'Plagl2' mRNA 468 525 430 4.61 5.08 4.49 5.06 4.81 4.42 4.726666667 4.763333333 592 549 500 474.3333333 547 0.142997022 0.195793811 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0009791///post-embryonic development+++GO:0034378///chylomicron assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 54712 54712 'Plxnc1' mRNA 206 248 235 1.49 1.76 1.8 2.86 3.01 2.89 1.683333333 2.92 456 468 447 229.6666667 457 5.80E-12 0.980533578 04360///Axon guidance GO:0002116///semaphorin receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017154///semaphorin receptor activity GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0043087///regulation of GTPase activity+++GO:0050772///positive regulation of axonogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 54713 54713 'Fezf2' mRNA 5 12 16 0.05 0.17 0.28 0.04 0.02 0.09 0.166666667 0.05 3 2 5 11 3.333333333 0.101217116 -1.749015847 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007413///axonal fasciculation+++GO:0007626///locomotory behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0016358///dendrite development+++GO:0021537///telencephalon development+++GO:0021542///dentate gyrus development+++GO:0021797///forebrain anterior/posterior pattern specification+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0043697///cell dedifferentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048664///neuron fate determination+++GO:0050767///regulation of neurogenesis+++GO:1902667///regulation of axon guidance" 547176 547176 'Zc3h12b' mRNA 267.62 224.19 289.58 2.06 1.57 2.26 0.88 1.09 1.11 1.963333333 1.026666667 138.38 164.03 171.6 260.4633333 158.0033333 2.10E-04 -0.73684669 GO:0005634///nucleus+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 54720 54720 'Rcan1' mRNA 1098 1188 1058 28.02 29.98 28.81 39.91 43.96 41.01 28.93666667 41.62666667 1787 1922 1779 1114.666667 1829.333333 1.93E-18 0.704894268 04919///Thyroid hormone signaling pathway+++04921///Oxytocin signaling pathway+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0042802///identical protein binding GO:0002931///response to ischemia+++GO:0006950///response to stress+++GO:0006979///response to oxidative stress+++GO:0007614///short-term memory+++GO:0019722///calcium-mediated signaling+++GO:0031987///locomotion involved in locomotory behavior+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0043627///response to estrogen+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0048741///skeletal muscle fiber development+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 54721 54721 'Tyk2' mRNA 507 469 435 5.78 5.19 5.21 6.83 6.42 6.76 5.393333333 6.67 698 636 673 470.3333333 669 7.87E-06 0.497467422 04217///Necroptosis+++04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05145///Toxoplasmosis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005131///growth hormone receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031702///type 1 angiotensin receptor binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035556///intracellular signal transduction 54722 54722 'Gsdme' mRNA 1356 1370 1310 7.73 7.52 7.76 6.95 6.03 6.37 7.67 6.45 1373 1188 1262 1345.333333 1274.333333 0.346903638 -0.090922873 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0022829///wide pore channel activity+++GO:1901612///cardiolipin binding" GO:0002839///positive regulation of immune response to tumor cell+++GO:0007605///sensory perception of sound+++GO:0008219///cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0012501///programmed cell death+++GO:0043410///positive regulation of MAPK cascade+++GO:0055085///transmembrane transport+++GO:0060113///inner ear receptor cell differentiation+++GO:0070265///necrotic cell death+++GO:0070269///pyroptosis+++GO:0071356///cellular response to tumor necrosis factor+++GO:0098586///cellular response to virus+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 54723 54723 'Tfip11' mRNA 834.73 831.91 814.12 12.78 12.53 13.22 11.44 10.52 11.59 12.84333333 11.18333333 859.58 772.18 843.33 826.92 825.03 0.901199684 -0.01553497 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0031012///extracellular matrix+++GO:0071008///U2-type post-mRNA release spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome" GO:0003676///nucleic acid binding+++GO:0005515///protein binding GO:0000390///spliceosomal complex disassembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0031214///biomineral tissue development+++GO:0031333///negative regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding 54725 54725 'Cadm1' mRNA 1976 1856 1978 20.93 19.24 23.09 17.46 14.65 15.31 21.08666667 15.80666667 1835 1514 1563 1936.666667 1637.333333 0.004943131 -0.2576359 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043196///varicosity+++GO:0045202///synapse+++GO:0070852///cell body fiber+++GO:0097060///synaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0001819///positive regulation of cytokine production+++GO:0001889///liver development+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007416///synapse assembly+++GO:0008037///cell recognition+++GO:0009826///unidimensional cell growth+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0030154///cell differentiation+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0051606///detection of stimulus+++GO:0060348///bone development+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0099054///presynapse assembly+++GO:0099560///synaptic membrane adhesion 547253 547253 'Parp14' mRNA 413 410 366 2.96 2.89 2.8 7.11 5.76 6.57 2.883333333 6.48 1139 903 1023 396.3333333 1021.666667 8.74E-36 1.354228885 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0003714///transcription corepressor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0070403///NAD+ binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0002376///immune system process+++GO:0006471///protein ADP-ribosylation+++GO:0010629///negative regulation of gene expression+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0070212///protein poly-ADP-ribosylation+++GO:1902216///positive regulation of interleukin-4-mediated signaling pathway" 547347 547347 'Gm6034' mRNA 5.05 9.08 11 0.18 0.32 0.42 0.59 0.16 0.26 0.306666667 0.336666667 19.09 5.04 8.06 8.376666667 10.73 0.779049753 0.324150927 GO:0005575///cellular_component+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 547431 547431 'Btnl2' mRNA 1101 1079 1001 23.88 23.04 23.03 5.17 4.09 4.21 23.31666667 4.49 274 212 216 1060.333333 234 4.34E-81 -2.192411173 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0050852///T cell receptor signaling pathway+++GO:0050860///negative regulation of T cell receptor signaling pathway 550619 550619 'Arid3c' mRNA 2 3 2 0.07 0.1 0.07 0 0 0 0.08 0 0 0 0 2.333333333 0 0.18180883 -3.671265478 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045121///membrane raft "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 553127 553127 'Rtl8b' mRNA 897.92 877.08 575.06 42.84 41.31 29.11 36.08 37.24 35.45 37.75333333 36.25666667 868.04 874.01 825 783.3533333 855.6833333 0.419855029 0.125067378 GO:0005575///cellular_component+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 554292 554292 'Methig1' mRNA 1.04 0 0 0.04 0 0 0.04 0 0.07 0.013333333 0.036666667 1.01 0 2 0.346666667 1.003333333 0.733992511 1.463929138 GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008168///methyltransferase activity GO:0008150///biological_process 554327 554327 '2610042L04Rik' mRNA 24.59 16.46 17.56 0.91 0.72 0.67 0.57 0.75 0.89 0.766666667 0.736666667 14.12 22.04 19.57 19.53666667 18.57666667 0.939808631 -0.058271832 GO:0005575///cellular_component GO:0005515///protein binding GO:0001933///negative regulation of protein phosphorylation+++GO:0007416///synapse assembly+++GO:0010821///regulation of mitochondrion organization+++GO:0060025///regulation of synaptic activity 55925 55925 'Syt8' mRNA 24 18 19 0.85 0.55 0.65 0.58 0.28 0.63 0.683333333 0.496666667 18 9 18 20.33333333 15 0.534748886 -0.453768238 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0070382///exocytic vesicle GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0048306///calcium-dependent protein binding GO:0006887///exocytosis+++GO:0007340///acrosome reaction+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0071277///cellular response to calcium ion 55927 55927 'Hes6' mRNA 666 764 544 29.55 33.44 25.46 24.63 25.37 25.39 29.48333333 25.13 631 636 631 658 632.6666667 0.691166251 -0.062607921 05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0009952///anterior/posterior pattern specification+++GO:0030154///cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0050767///regulation of neurogenesis" 55932 55932 'Gbp3' mRNA 1524.7 1565.89 1564.75 30.7 31.05 33.36 38.91 38.06 37.37 31.70333333 38.11333333 2229.16 2128.1 2067.42 1551.78 2141.56 1.41E-09 0.452220995 04621///NOD-like receptor signaling pathway GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032687///negative regulation of interferon-alpha production+++GO:0035458///cellular response to interferon-beta+++GO:0042308///negative regulation of protein import into nucleus+++GO:0042832///defense response to protozoan+++GO:0044406///adhesion of symbiont to host+++GO:0050688///regulation of defense response to virus+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071346///cellular response to interferon-gamma 55934 55934 'Rp9' mRNA 607 632 554 32.97 33.92 31.93 31.68 32.1 30.51 32.94 31.43 669 661 623 597.6666667 651 0.36078091 0.113261372 03040///Spliceosome GO:0005634///nucleus+++GO:0005785///signal recognition particle receptor complex+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008380///RNA splicing+++GO:0050890///cognition 55935 55935 'Fnbp4' mRNA 1605 1691 1472 19.13 19.86 18.61 15.53 14.23 15.38 19.2 15.04666667 1493 1339 1439 1589.333333 1423.666667 0.038573006 -0.169380264 GO:0016607///nuclear speck GO:0005515///protein binding GO:0008150///biological_process 55936 55936 'Ctps2' mRNA 876 921 772 12.47 12.58 11.31 12.82 12.99 12.74 12.12 12.85 1024 1012 976 856.3333333 1004 0.021748514 0.220378371 00240///Pyrimidine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0097268///cytoophidium GO:0000166///nucleotide binding+++GO:0003883///CTP synthase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0019856///pyrimidine nucleobase biosynthetic process+++GO:0044210///'de novo' CTP biosynthetic process 55938 55938 'Apom' mRNA 3 0 2 0.27 0 0.19 0.16 0.08 0.33 0.153333333 0.19 2 1 4 1.666666667 2.333333333 0.862099428 0.461576773 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034362///low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0034365///discoidal high-density lipoprotein particle+++GO:0034366///spherical high-density lipoprotein particle GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0016209///antioxidant activity GO:0006869///lipid transport+++GO:0009749///response to glucose+++GO:0033344///cholesterol efflux+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034384///high-density lipoprotein particle clearance+++GO:0034445///negative regulation of plasma lipoprotein oxidation+++GO:0042157///lipoprotein metabolic process+++GO:0043691///reverse cholesterol transport+++GO:0098869///cellular oxidant detoxification 55942 55942 'Sertad1' mRNA 625 598 560 32.35 30.58 30.76 54.08 51.98 53.38 31.23 53.14666667 1198 1124 1144 594.3333333 1155.333333 5.87E-26 0.947861567 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0140110///transcription regulator activity "GO:0030308///negative regulation of cell growth+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048096///chromatin-mediated maintenance of transcription" 55943 55943 'Stx8' mRNA 698.01 769 735 35.01 39.84 43.16 39.45 35.31 43.72 39.33666667 39.49333333 817.81 794 820 734.0033333 810.6033333 0.251777794 0.13048398 04130///SNARE interactions in vesicular transport GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019869///chloride channel inhibitor activity+++GO:0019905///syntaxin binding+++GO:0031625///ubiquitin protein ligase binding GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0008333///endosome to lysosome transport+++GO:0016192///vesicle-mediated transport+++GO:0045022///early endosome to late endosome transport+++GO:0048278///vesicle docking+++GO:0071346///cellular response to interferon-gamma+++GO:1903076///regulation of protein localization to plasma membrane 55944 55944 'Eif3d' mRNA 1486 1612 1513 44.44 47.51 47.98 56.71 58.01 57.11 46.64333333 57.27666667 2185 2179 2124 1537 2162.666667 4.14E-11 0.48104853 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0098808///mRNA cap binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0002191///cap-dependent translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0045727///positive regulation of translation+++GO:0075522///IRES-dependent viral translational initiation+++GO:0075525///viral translational termination-reinitiation+++GO:1902416///positive regulation of mRNA binding 55946 55946 'Ap3m1' mRNA 953 1111 1083 14.66 16.63 17.89 19.64 19.55 19.86 16.39333333 19.68333333 1438 1376 1394 1049 1402.666667 1.45E-05 0.405731426 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030131///clathrin adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1904115///axon cytoplasm GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048490///anterograde synaptic vesicle transport 55947 55947 'Dclre1a' mRNA 462 425 371 6.39 5.71 5.48 3.94 3.53 3.66 5.86 3.71 330 300 302 419.3333333 310.6666667 0.001532053 -0.442370896 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0036297///interstrand cross-link repair+++GO:0051301///cell division+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 55948 55948 'Sfn' mRNA 50 46 36 1.81 1.64 1.38 12.37 12.19 10.83 1.61 11.79666667 392 377 332 44 367 2.49E-50 3.051107393 04110///Cell cycle+++04115///p53 signaling pathway+++04960///Aldosterone-regulated sodium reabsorption GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001836///release of cytochrome c from mitochondria+++GO:0003334///keratinocyte development+++GO:0007165///signal transduction+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010482///regulation of epidermal cell division+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0030216///keratinocyte differentiation+++GO:0030307///positive regulation of cell growth+++GO:0031424///keratinization+++GO:0034613///cellular protein localization+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043588///skin development+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0051726///regulation of cell cycle+++GO:0061436///establishment of skin barrier 55949 55949 'Eef1b2' mRNA 1668 1613 1622 49.32 46.99 50.87 78.16 68.5 80.41 49.06 75.69 3039 2600 3026 1634.333333 2888.333333 4.03E-26 0.80805785 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005853///eukaryotic translation elongation factor 1 complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003746///translation elongation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0045471///response to ethanol+++GO:0050790///regulation of catalytic activity 55950 55950 'Bri3' mRNA 449 383 148 30.44 25.71 11.2 18.92 17.26 22.49 22.45 19.55666667 318 286 363 326.6666667 322.3333333 0.99270206 -0.011067346 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding 55951 55951 'Mpc1' mRNA 3238 3304 3042 223.35 225.31 222.46 228.63 229.01 230.44 223.7066667 229.36 3796 3707 3695 3194.666667 3732.666667 3.12E-04 0.213625656 05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0050833///pyruvate transmembrane transporter activity GO:0006850///mitochondrial pyruvate transmembrane transport+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate+++GO:1990830///cellular response to leukemia inhibitory factor 55960 55960 'Ebag9' mRNA 364 445 334 10.01 12.22 9.78 6.26 7.11 7.61 10.67 6.993333333 265 281 303 381 283 0.005207358 -0.435946199 04915///Estrogen signaling pathway GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule GO:0006915///apoptotic process 55961 55961 'Slc13a1' mRNA 1 3 2 0.02 0.12 0.05 0 0.02 0 0.063333333 0.006666667 0 1 0 2 0.333333333 0.376240056 -2.490403728 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015382///sodium:sulfate symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008272///sulfate transport+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902358///sulfate transmembrane transport 55963 55963 'Slc1a4' mRNA 1588 1651 1646 21.86 22.35 24.03 7.77 6.49 7.28 22.74666667 7.18 650 530 590 1628.333333 590 5.26E-57 -1.47897392 GO:0005813///centrosome+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042470///melanosome+++GO:0043025///neuronal cell body GO:0005254///chloride channel activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015184///L-cystine transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0015195///L-threonine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0034590///L-hydroxyproline transmembrane transporter activity GO:0015698///inorganic anion transport+++GO:0015808///L-alanine transport+++GO:0015811///L-cystine transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0015824///proline transport+++GO:0015825///L-serine transport+++GO:0015826///threonine transport+++GO:0034589///hydroxyproline transport+++GO:0035524///proline transmembrane transport+++GO:0050890///cognition+++GO:0055085///transmembrane transport+++GO:0098718///serine import across plasma membrane+++GO:0140009///L-aspartate import across plasma membrane+++GO:1903812///L-serine import across plasma membrane+++GO:1904273///L-alanine import across plasma membrane 55978 55978 'Ift20' mRNA 889 877 814 48.6 47.37 47.22 44.79 49.99 45.69 47.73 46.82333333 940 1023 927 860 963.3333333 0.14416898 0.153716633 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0044292///dendrite terminus+++GO:0097546///ciliary base+++GO:1902636///kinociliary basal body GO:0002046///opsin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0007224///smoothened signaling pathway+++GO:0007283///spermatogenesis+++GO:0008542///visual learning+++GO:0022008///neurogenesis+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0034067///protein localization to Golgi apparatus+++GO:0035845///photoreceptor cell outer segment organization+++GO:0036372///opsin transport+++GO:0042073///intraciliary transport+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0051642///centrosome localization+++GO:0055007///cardiac muscle cell differentiation+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060271///cilium assembly+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061351///neural precursor cell proliferation+++GO:0061512///protein localization to cilium+++GO:0072659///protein localization to plasma membrane+++GO:0090102///cochlea development+++GO:1902017///regulation of cilium assembly+++GO:1903441///protein localization to ciliary membrane+++GO:2000583///regulation of platelet-derived growth factor receptor-alpha signaling pathway+++GO:2000785///regulation of autophagosome assembly 55979 55979 'Agpat1' mRNA 1129.61 1177.91 907.8 29.71 31.25 25.59 29.61 23.61 27.21 28.85 26.81 1283.93 1016.11 1136.01 1071.773333 1145.35 0.488495911 0.087420171 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04072///Phospholipase D signaling pathway+++04975///Fat digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0001819///positive regulation of cytokine production+++GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process 55980 55980 'Impa1' mRNA 1208 1295 1267 28.28 29.99 31.41 31.82 30.79 31.72 29.89333333 31.44333333 1561 1469 1508 1256.666667 1512.666667 0.002526615 0.254547846 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0000287///magnesium ion binding+++GO:0008934///inositol monophosphate 1-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0031403///lithium ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0052832///inositol monophosphate 3-phosphatase activity+++GO:0052833///inositol monophosphate 4-phosphatase activity+++GO:0052834///inositol monophosphate phosphatase activity GO:0006020///inositol metabolic process+++GO:0006021///inositol biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006796///phosphate-containing compound metabolic process+++GO:0007165///signal transduction+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046855///inositol phosphate dephosphorylation 55981 55981 'Pigb' mRNA 667.45 678.07 665.41 11.11 10.6 11.86 9.04 10.18 8.55 11.19 9.256666667 634.15 640.04 559.91 670.31 611.3666667 0.246130284 -0.145201854 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000026///alpha-1,2-mannosyltransferase activity+++GO:0000030///mannosyltransferase activity+++GO:0004376///glycolipid mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006505///GPI anchor metabolic process+++GO:0006506///GPI anchor biosynthetic process+++GO:0097502///mannosylation 55982 55982 'Paxip1' mRNA 391.19 512.8 378.61 3.69 4.74 3.84 3.29 2.92 2.65 4.09 2.953333333 386.23 337.28 318.74 427.5333333 347.4166667 0.050396784 -0.308337019 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016363///nuclear matrix+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex GO:0005515///protein binding "GO:0000416///positive regulation of histone H3-K36 methylation+++GO:0001570///vasculogenesis+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0031398///positive regulation of protein ubiquitination+++GO:0035066///positive regulation of histone acetylation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043542///endothelial cell migration+++GO:0045830///positive regulation of isotype switching+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0051568///histone H3-K4 methylation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0060612///adipose tissue development+++GO:0060717///chorion development+++GO:1902749///regulation of cell cycle G2/M phase transition+++GO:2001022///positive regulation of response to DNA damage stimulus" 55983 55983 'Pdzrn3' mRNA 362 392 375 5.41 5.76 5.96 2 1.59 1.59 5.71 1.726666667 157 120 118 376.3333333 131.6666667 5.97E-20 -1.529363226 GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0045202///synapse GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007528///neuromuscular junction development+++GO:0016567///protein ubiquitination 55984 55984 'Camkk1' mRNA 74 68 57 1.16 1.02 0.95 0.94 0.75 0.8 1.043333333 0.83 69 54 57 66.33333333 60 0.708766553 -0.154939463 05034///Alcoholism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0045860///positive regulation of protein kinase activity 55985 55985 'Cxcl13' mRNA 13 6 19 0.69 0.32 1.07 0.83 1.19 1.01 0.693333333 1.01 18 25 21 12.66666667 21.33333333 0.32119093 0.726702881 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0017134///fibroblast growth factor binding+++GO:0031724///CXCR5 chemokine receptor binding+++GO:0031735///CCR10 chemokine receptor binding+++GO:0045236///CXCR chemokine receptor binding+++GO:0048018///receptor ligand activity+++GO:0048248///CXCR3 chemokine receptor binding GO:0002518///lymphocyte chemotaxis across high endothelial venule+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007267///cell-cell signaling+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0035754///B cell chemotaxis+++GO:0035768///endothelial cell chemotaxis to fibroblast growth factor+++GO:0035769///B cell chemotaxis across high endothelial venule+++GO:0042742///defense response to bacterium+++GO:0048535///lymph node development+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090630///activation of GTPase activity+++GO:2000545///negative regulation of endothelial cell chemotaxis to fibroblast growth factor 55987 55987 'Cpxm2' mRNA 2892 3029 2865 52.54 53.5 55.46 46.94 49.42 44.17 53.83333333 46.84333333 3056 2876 2747 2928.666667 2893 0.743620693 -0.029935907 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016485///protein processing 55988 55988 'Snx12' mRNA 678.54 725.73 645.37 21.51 22.62 23.19 27.25 27.08 28.36 22.44 27.56333333 944.98 860.34 991.95 683.2133333 932.4233333 1.13E-05 0.437773055 04144///Endocytosis GO:0005769///early endosome+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0031901///early endosome membrane GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding GO:0010629///negative regulation of gene expression+++GO:0010955///negative regulation of protein processing+++GO:0015031///protein transport+++GO:0030100///regulation of endocytosis+++GO:0032456///endocytic recycling+++GO:0034499///late endosome to Golgi transport+++GO:0042177///negative regulation of protein catabolic process+++GO:0051224///negative regulation of protein transport+++GO:2000642///negative regulation of early endosome to late endosome transport 55989 55989 'Nop58' mRNA 603 652 620 17.26 18.32 18.78 26.75 24.3 26.35 18.12 25.8 1075 955 1029 625 1019.666667 5.76E-13 0.693463511 03008///Ribosome biogenesis in eukaryotes GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0031428///box C/D snoRNP complex+++GO:0032040///small-subunit processome+++GO:0070761///pre-snoRNP complex GO:0001094///TFIID-class transcription factor complex binding+++GO:0030515///snoRNA binding+++GO:0051117///ATPase binding GO:0042254///ribosome biogenesis+++GO:0048254///snoRNA localization 55990 55990 'Fmo2' mRNA 132 96 91 1.72 1.21 1.25 0.73 0.61 0.77 1.393333333 0.703333333 64 52 66 106.3333333 60.66666667 0.00511944 -0.819405511 00982///Drug metabolism - cytochrome P450 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding" GO:0006082///organic acid metabolic process+++GO:0006739///NADP metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0009404///toxin metabolic process+++GO:0017144///drug metabolic process+++GO:0070995///NADPH oxidation+++GO:0072592///oxygen metabolic process 55991 55991 'Panx1' mRNA 542 516 357 14.81 13.89 10.35 3.61 5.55 4.81 13.01666667 4.656666667 152 228 196 471.6666667 192 1.27E-12 -1.297174283 04621///NOD-like receptor signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032059///bleb+++GO:0032991///protein-containing complex GO:0002020///protease binding+++GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005198///structural molecule activity+++GO:0005243///gap junction channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0015267///channel activity+++GO:0022829///wide pore channel activity+++GO:0022840///leak channel activity+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0055077///gap junction hemi-channel activity+++GO:0097110///scaffold protein binding GO:0001819///positive regulation of cytokine production+++GO:0002931///response to ischemia+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0007267///cell-cell signaling+++GO:0032730///positive regulation of interleukin-1 alpha production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032732///positive regulation of interleukin-1 production+++GO:0033198///response to ATP+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport 55992 55992 'Trim3' mRNA 325 343 324 6.25 6.45 6.6 6.07 5.53 5.72 6.433333333 5.773333333 364 323 333 330.6666667 340 0.876679435 0.02770512 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 55993 55993 'Msh4' mRNA 1 0 0 0.02 0 0 0.03 0 0.02 0.006666667 0.016666667 2 0 1 0.333333333 1 0.736887967 1.452215211 GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005713///recombination nodule+++GO:0032301///MutSalpha complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0030983///mismatched DNA binding GO:0000710///meiotic mismatch repair+++GO:0000712///resolution of meiotic recombination intermediates+++GO:0001541///ovarian follicle development+++GO:0006281///DNA repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0007292///female gamete generation+++GO:0051321///meiotic cell cycle 55994 55994 'Smad9' mRNA 11.82 11 9.07 0.11 0.11 0.08 0.03 0.02 0.05 0.1 0.033333333 2.98 3 6 10.63 3.993333333 0.152405931 -1.499813251 04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071144///heteromeric SMAD protein complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0070411///I-SMAD binding" "GO:0001657///ureteric bud development+++GO:0001880///Mullerian duct regression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0045597///positive regulation of cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051216///cartilage development+++GO:0060348///bone development+++GO:0060395///SMAD protein signal transduction+++GO:0071407///cellular response to organic cyclic compound" 56009 56009 'Alyref2' mRNA 190 270 232 9.06 12.72 11.74 10.18 9.54 9.76 11.17333333 9.826666667 245 224 227 230.6666667 232 0.994139137 -0.003974949 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome+++05014///Amyotrophic lateral sclerosis+++05168///Herpes simplex virus 1 infection "GO:0000346///transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0035145///exon-exon junction complex+++GO:0071013///catalytic step 2 spliceosome" GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000018///regulation of DNA recombination+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport" 56012 56012 'Pgam2' mRNA 20 18 29 1.45 1.29 2.23 0.57 0.58 0.92 1.656666667 0.69 9 9 14 22.33333333 10.66666667 0.106243642 -1.087674625 "00010///Glycolysis / Gluconeogenesis+++00260///Glycine, serine and threonine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer" GO:0005634///nucleus+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0004082///bisphosphoglycerate mutase activity+++GO:0004619///phosphoglycerate mutase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0042802///identical protein binding+++GO:0046538///2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity" GO:0006094///gluconeogenesis+++GO:0006096///glycolytic process+++GO:0006941///striated muscle contraction+++GO:0007219///Notch signaling pathway+++GO:0007283///spermatogenesis+++GO:0010035///response to inorganic substance+++GO:0046689///response to mercury ion 56013 56013 'Srcin1' mRNA 499 358 269 3.75 2.68 2.2 0.83 0.92 1.11 2.876666667 0.953333333 126 137 164 375.3333333 142.3333333 1.73E-11 -1.40112556 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030234///enzyme regulator activity GO:0006887///exocytosis+++GO:0007162///negative regulation of cell adhesion+++GO:0030334///regulation of cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0050709///negative regulation of protein secretion+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061099///negative regulation of protein tyrosine kinase activity 56014 56014 'Olfr70' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 56015 56015 'Olfr71' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 56016 56016 'Hebp2' mRNA 2062 2120 2056 61.78 62.59 65.35 30.6 30.25 26.8 63.24 29.21666667 1174 1133 995 2079.333333 1100.666667 5.89E-30 -0.930369035 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0020037///heme binding GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0010940///positive regulation of necrotic cell death+++GO:0035794///positive regulation of mitochondrial membrane permeability 56017 56017 'Slc2a8' mRNA 993 998 955 26.49 26.27 27.03 23.62 21.97 21.14 26.59666667 22.24333333 1014 923 878 982 938.3333333 0.489180327 -0.078030204 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005353///fructose transmembrane transporter activity+++GO:0005354///galactose transmembrane transporter activity+++GO:0005355///glucose transmembrane transporter activity+++GO:0005536///glucose binding+++GO:0015284///fructose uniporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity GO:0001666///response to hypoxia+++GO:0006006///glucose metabolic process+++GO:0007141///male meiosis I+++GO:0008286///insulin receptor signaling pathway+++GO:0008643///carbohydrate transport+++GO:0015755///fructose transmembrane transport+++GO:0015757///galactose transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070837///dehydroascorbic acid transport+++GO:1904659///glucose transmembrane transport 56018 56018 'Stard10' mRNA 1751 1645 1358 79.07 72.99 64.65 27.02 23.62 26.86 72.23666667 25.83333333 697 598 675 1584.666667 656.6666667 4.91E-41 -1.279577784 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0046581///intercellular canaliculus GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0032782///bile acid secretion+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway 56030 56030 'Tmem131' mRNA 712 694 674 5.74 5.5 5.76 4.99 4.46 4.62 5.666666667 4.69 713 622 639 693.3333333 658 0.489355827 -0.088131044 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 56031 56031 'Ppie' mRNA 659 655 630 33.88 33.46 34.41 28.28 32.9 28.74 33.91666667 29.97333333 629 713 617 648 653 0.998591786 5.63E-04 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0008143///poly(A) binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006457///protein folding+++GO:0008380///RNA splicing+++GO:0045070///positive regulation of viral genome replication" 56032 56032 'Nprl2' mRNA 1038 937 992 43.38 38.58 43.92 23.82 24.83 25.73 41.96 24.79333333 662 673 691 989 675.3333333 2.11E-08 -0.563002549 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:1990130///GATOR1 complex GO:0004672///protein kinase activity+++GO:0005096///GTPase activator activity GO:0006468///protein phosphorylation+++GO:0006995///cellular response to nitrogen starvation+++GO:0010508///positive regulation of autophagy+++GO:0032007///negative regulation of TOR signaling+++GO:0033673///negative regulation of kinase activity+++GO:0034198///cellular response to amino acid starvation+++GO:0043547///positive regulation of GTPase activity+++GO:2000785///regulation of autophagosome assembly 56036 56036 'Ccnl2' mRNA 3345.71 3530.91 2920.88 60.04 62.18 55.42 46.05 52.44 49.9 59.21333333 49.46333333 2910.53 3198.85 3068.48 3265.833333 3059.286667 0.218146024 -0.101684431 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity 56040 56040 'Rplp1' mRNA 4811 4284 4681 911.62 813.71 941.96 987.85 1005.18 1053.12 889.0966667 1015.383333 5918 5837 6064 4592 5939.666667 5.56E-07 0.357514056 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003735///structural constituent of ribosome+++GO:0030295///protein kinase activator activity+++GO:0043021///ribonucleoprotein complex binding GO:0002181///cytoplasmic translation+++GO:0006414///translational elongation+++GO:0006417///regulation of translation+++GO:0032147///activation of protein kinase activity 56041 56041 'Uso1' mRNA 464 526 427 6.42 7.17 6.28 7.85 8.16 7.52 6.623333333 7.843333333 653 662 605 472.3333333 640 2.54E-04 0.429359663 GO:0000139///Golgi membrane+++GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032252///secretory granule localization+++GO:0045056///transcytosis+++GO:0048211///Golgi vesicle docking+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0061025///membrane fusion+++GO:1900076///regulation of cellular response to insulin stimulus 56043 56043 'Akr1e1' mRNA 623.24 619.82 610.03 19.28 19.35 20.78 17.7 18.59 16.03 19.80333333 17.44 618 645.99 545.9 617.6966667 603.2966667 0.764695166 -0.046564972 GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0050571///1,5-anhydro-D-fructose reductase activity" 56044 56044 'Rala' mRNA 1328 1324 1223 27.65 27.14 27.01 30.37 30.97 31.2 27.26666667 30.84666667 1678 1671 1669 1291.666667 1672.666667 1.41E-06 0.362311513 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++05132///Salmonella infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0032154///cleavage furrow+++GO:0043209///myelin sheath+++GO:0090543///Flemming body GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0017022///myosin binding+++GO:0019003///GDP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031755///Edg-2 lysophosphatidic acid receptor binding+++GO:0051117///ATPase binding GO:0001843///neural tube closure+++GO:0006887///exocytosis+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0017157///regulation of exocytosis+++GO:0031532///actin cytoskeleton reorganization+++GO:0051301///cell division+++GO:0051491///positive regulation of filopodium assembly+++GO:0051665///membrane raft localization+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0090141///positive regulation of mitochondrial fission 56045 56045 'Samhd1' mRNA 585 606 584 10.28 10.46 9.76 36.05 35.73 36.66 10.16666667 36.14666667 2548 2350 2573 591.6666667 2490.333333 1.18E-150 2.061355058 05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005886///plasma membrane+++GO:0035861///site of double-strand break+++GO:0097197///tetraspanin-enriched microdomain GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004540///ribonuclease activity+++GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0008832///dGTPase activity+++GO:0016787///hydrolase activity+++GO:0016793///triphosphoric monoester hydrolase activity+++GO:0032567///dGTP binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000724///double-strand break repair via homologous recombination+++GO:0002376///immune system process+++GO:0006203///dGTP catabolic process+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0009264///deoxyribonucleotide catabolic process+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0046061///dATP catabolic process+++GO:0051289///protein homotetramerization+++GO:0051607///defense response to virus+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0110025///DNA strand resection involved in replication fork processing 56046 56046 'Uqcc1' mRNA 1621.07 1722.8 1584.42 32.51 33.48 33.56 17.95 19.29 19.63 33.18333333 18.95666667 1043.44 1093.66 1095.89 1642.763333 1077.663333 8.35E-15 -0.619308996 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0070131///positive regulation of mitochondrial translation 56047 56047 'Msln' mRNA 336 308 323 8.98 8.26 9.24 20.44 23.22 20 8.826666667 21.22 867 965 830 322.3333333 887.3333333 4.57E-35 1.449352456 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0031016///pancreas development 56048 56048 'Lgals8' mRNA 1310 1214 1276 26.14 24.06 27.29 30.14 29.62 30.13 25.83 29.96333333 1732 1638 1658 1266.666667 1676 1.97E-06 0.390643584 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle GO:0005178///integrin binding+++GO:0030246///carbohydrate binding GO:0002317///plasma cell differentiation+++GO:0006914///autophagy+++GO:0031295///T cell costimulation+++GO:0098586///cellular response to virus+++GO:0098792///xenophagy+++GO:1904977///lymphatic endothelial cell migration 56050 56050 'Cyp39a1' mRNA 1071 1063 1082 19.22 18.68 20.56 14.62 12.96 14.77 19.48666667 14.11666667 944 816 922 1072 894 0.005070189 -0.275791383 00120///Primary bile acid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008387///steroid 7-alpha-hydroxylase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008396///oxysterol 7-alpha-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0033782///24-hydroxycholesterol 7alpha-hydroxylase activity+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006707///cholesterol catabolic process+++GO:0007586///digestion+++GO:0008202///steroid metabolic process+++GO:0016042///lipid catabolic process+++GO:0030573///bile acid catabolic process+++GO:0042632///cholesterol homeostasis 56055 56055 'Gtpbp2' mRNA 577 551 458 10.15 9.44 8.32 8.25 8.87 8.14 9.303333333 8.42 545 571 517 528.6666667 544.3333333 0.845963899 0.034284436 GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding "GO:0006414///translational elongation+++GO:0070966///nuclear-transcribed mRNA catabolic process, no-go decay+++GO:0072344///rescue of stalled ribosome" 56057 56057 'Btg4' mRNA 2 1 1 0.08 0.04 0.03 0 0.03 0 0.05 0.01 0 1 0 1.333333333 0.333333333 0.574922392 -1.902275385 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0008285///negative regulation of cell proliferation+++GO:0045930///negative regulation of mitotic cell cycle 56068 56068 'Ammecr1' mRNA 70 75 53 0.69 0.72 0.55 0.72 0.88 0.84 0.653333333 0.813333333 85 101 96 66 94 0.09557368 0.505439173 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 56069 56069 'Il17b' mRNA 52 50 38 5.39 5.15 4.09 3.27 3.17 2.74 4.876666667 3.06 36 34 29 46.66666667 33 0.246452989 -0.507259209 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0030593///neutrophil chemotaxis+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 56070 56070 'Tcerg1' mRNA 1710 1693 1625 20.97 20.45 21.12 19.22 17.87 18.47 20.84666667 18.52 1803 1638 1677 1676 1706 0.888377162 0.013354011 03040///Spliceosome+++04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070063///RNA polymerase binding+++GO:0070064///proline-rich region binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045944///positive regulation of transcription by RNA polymerase II" 56072 56072 'Lgals12' mRNA 4 3 0 0.09 0.07 0 0.12 0.16 0.2 0.053333333 0.16 7 8 10 2.333333333 8.333333333 0.147191154 1.84905046 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030246///carbohydrate binding+++GO:0030395///lactose binding+++GO:0035259///glucocorticoid receptor binding "GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0016358///dendrite development+++GO:0045598///regulation of fat cell differentiation+++GO:0050994///regulation of lipid catabolic process+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0150012///positive regulation of neuron projection arborization+++GO:1904977///lymphatic endothelial cell migration" 56075 56075 'Pdss1' mRNA 172.45 147.12 166.3 4.32 3.81 4.77 6.05 4.89 5.43 4.3 5.456666667 234.14 192 212.46 161.9566667 212.8666667 0.059256362 0.380569551 00900///Terpenoid backbone biosynthesis GO:0005739///mitochondrion+++GO:1990234///transferase complex GO:0000010///trans-hexaprenyltranstransferase activity+++GO:0004659///prenyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050347///trans-octaprenyltranstransferase activity+++GO:0097269///all-trans-decaprenyl-diphosphate synthase activity GO:0006744///ubiquinone biosynthetic process+++GO:0008299///isoprenoid biosynthetic process 56077 56077 'Dgke' mRNA 562.51 630.07 549.39 3.87 4.27 4.02 2.96 2.88 2.89 4.053333333 2.91 494.1 469 470.12 580.6566667 477.74 0.014218541 -0.291554982 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++04361///Axon regeneration+++05231///Choline metabolism in cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006654///phosphatidic acid biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046339///diacylglycerol metabolic process+++GO:0046486///glycerolipid metabolic process+++GO:0046834///lipid phosphorylation+++GO:0050804///modulation of chemical synaptic transmission 56078 56078 'Car5b' mRNA 66.5 55.84 73.16 1.05 0.87 1.22 1.22 1.14 1.38 1.046666667 1.246666667 88.91 80.86 97.59 65.16666667 89.12 0.178245589 0.433106078 00910///Nitrogen metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0009617///response to bacterium 56079 56079 'Astn2' mRNA 9 19 9 0.08 0.19 0.05 0.01 0.03 0.05 0.106666667 0.03 1 4 5 12.33333333 3.333333333 0.066909539 -1.881941133 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043204///perikaryon+++GO:0060187///cell pole "GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0043533///inositol 1,3,4,5 tetrakisphosphate binding+++GO:0046872///metal ion binding" GO:0001764///neuron migration+++GO:0007158///neuron cell-cell adhesion+++GO:0015031///protein transport+++GO:0048105///establishment of body hair planar orientation+++GO:2000009///negative regulation of protein localization to cell surface 56085 56085 'Ubqln1' mRNA 3040 3319 1365 45.41 48.7 21.55 15.57 24.47 24.63 38.55333333 21.55666667 1200 1848 1839 2574.666667 1629 0.171171346 -0.648831394 04141///Protein processing in endoplasmic reticulum+++05014///Amyotrophic lateral sclerosis GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005102///signaling receptor binding+++GO:0019215///intermediate filament binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding GO:0000045///autophagosome assembly+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0016236///macroautophagy+++GO:0016241///regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031396///regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034140///negative regulation of toll-like receptor 3 signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035973///aggrephagy+++GO:0071456///cellular response to hypoxia+++GO:0097352///autophagosome maturation+++GO:1901340///negative regulation of store-operated calcium channel activity+++GO:1902175///regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process 56086 56086 'Set' mRNA 3524 3249 3579 72.36 65.78 78.06 96.89 91.59 93.89 72.06666667 94.12333333 5414 4999 5076 3450.666667 5163 2.22E-15 0.566317743 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0042393///histone binding "GO:0006334///nucleosome assembly+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated" 56087 56087 'Dnah10' mRNA 217 254 230 0.83 0.95 0.91 0.1 0.08 0.12 0.896666667 0.1 31 24 34 233.6666667 29.66666667 6.07E-33 -2.989890183 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement 56088 56088 'Psmg1' mRNA 557 554 560 33.76 33.2 36.01 33.14 37.03 33.36 34.32333333 34.51 627 683 610 557 640 0.13215715 0.188509527 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0101031///chaperone complex GO:0060090///molecular adaptor activity+++GO:0070628///proteasome binding GO:0021930///cerebellar granule cell precursor proliferation+++GO:0043248///proteasome assembly+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0080129///proteasome core complex assembly 56089 56089 'Ramp3' mRNA 13 5 29 0.65 0.25 1.54 2.66 3.42 1.72 0.813333333 2.6 61 78 38 15.66666667 59 7.17E-04 1.876711082 04270///Vascular smooth muscle contraction GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0150058///amylin receptor complex 3+++GO:1903143///adrenomedullin receptor complex GO:0001605///adrenomedullin receptor activity+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity GO:0001525///angiogenesis+++GO:0001921///positive regulation of receptor recycling+++GO:0006816///calcium ion transport+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0010942///positive regulation of cell death+++GO:0015031///protein transport+++GO:0031623///receptor internalization+++GO:0032870///cellular response to hormone stimulus+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038041///cross-receptor inhibition within G protein-coupled receptor heterodimer+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071392///cellular response to estradiol stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0086103///G protein-coupled receptor signaling pathway involved in heart process+++GO:0097647///amylin receptor signaling pathway+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904645///response to amyloid-beta+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:1990410///adrenomedullin receptor signaling pathway 56094 56094 'Cts8' mRNA 0 1.49 0 0 0.03 0 0.02 0 0.02 0.01 0.013333333 1.03 0 1.08 0.496666667 0.703333333 0.863090843 0.873430513 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001968///fibronectin binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005518///collagen binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0043394///proteoglycan binding+++GO:0097655///serpin family protein binding GO:0001974///blood vessel remodeling+++GO:0006508///proteolysis+++GO:0006955///immune response+++GO:0016540///protein autoprocessing+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0030163///protein catabolic process+++GO:0030574///collagen catabolic process+++GO:0031638///zymogen activation+++GO:0039654///fusion of virus membrane with host endosome membrane+++GO:0046718///viral entry into host cell+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060707///trophoblast giant cell differentiation 56095 56095 'Ftsj3' mRNA 587 592 601 10.19 10.11 11.07 14.15 13.81 15.04 10.45666667 14.33333333 938 894 965 593.3333333 932.3333333 1.38E-10 0.639139761 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0030688///preribosome, small subunit precursor" GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0008650///rRNA (uridine-2'-O-)-methyltransferase activity+++GO:0016435///rRNA (guanine) methyltransferase activity+++GO:0016740///transferase activity "GO:0000453///enzyme-directed rRNA 2'-O-methylation+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0042254///ribosome biogenesis" 56149 56149 'Grasp' mRNA 121 93 14 3.42 2.59 0.42 0.49 1.23 0.96 2.143333333 0.893333333 20 49 38 76 35.66666667 0.303812415 -1.064345164 GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding "GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0008104///protein localization+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane" 56150 56150 'Mad2l1' mRNA 150 140 95 4.98 4.44 3.38 12.98 12.47 12.64 4.266666667 12.69666667 459 417 420 128.3333333 432 1.50E-25 1.744927878 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0044615///nuclear pore nuclear basket+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle" GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000070///mitotic sister chromatid segregation+++GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045841///negative regulation of mitotic metaphase/anaphase transition+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0051660///establishment of centrosome localization+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1904667///negative regulation of ubiquitin protein ligase activity 56173 56173 'Cldn14' mRNA 622 562 566 27.16 23.91 24.7 6.51 5.99 6.38 25.25666667 6.293333333 175 164 173 583.3333333 170.6666667 8.41E-40 -1.785288788 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 56174 56174 'Nagk' mRNA 898 951 900 40.21 42.26 42.67 54.19 54.03 54.31 41.71333333 54.17666667 1383 1340 1336 916.3333333 1353 3.03E-11 0.550402813 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0045127///N-acetylglucosamine kinase activity GO:0006044///N-acetylglucosamine metabolic process+++GO:0016310///phosphorylation+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0046835///carbohydrate phosphorylation 56175 56175 'Bace2' mRNA 691 739 669 18.05 19.2 18.39 20.82 20.52 22.24 18.54666667 21.19333333 925 866 915 699.6666667 902 2.29E-04 0.355301217 05010///Alzheimer disease GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031045///dense core granule GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0042593///glucose homeostasis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0048143///astrocyte activation+++GO:0050435///amyloid-beta metabolic process 56176 56176 'Pigp' mRNA 1664.37 1596.08 1594.02 146.51 137.69 148.89 106.06 106.94 105.87 144.3633333 106.29 1400.58 1376.21 1348.96 1618.156667 1375.25 0.002014827 -0.247351593 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0006506///GPI anchor biosynthetic process 56177 56177 'Olfm1' mRNA 246 265 141 7.05 7.12 4.11 3.87 4.47 4.4 6.093333333 4.246666667 195 216 196 217.3333333 202.3333333 0.726303728 -0.102360699 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032281///AMPA glutamate receptor complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0044295///axonal growth cone+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099243///extrinsic component of synaptic membrane GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0003190///atrioventricular valve formation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0023041///neuronal signal transduction+++GO:0030516///regulation of axon extension+++GO:0043065///positive regulation of apoptotic process+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:1902003///regulation of amyloid-beta formation+++GO:1902430///negative regulation of amyloid-beta formation+++GO:2001223///negative regulation of neuron migration 56183 56183 'Nmu' mRNA 0 2 3 0 0.16 0.26 0.43 0.3 1.12 0.14 0.616666667 6 4 15 1.666666667 8.333333333 0.095452022 2.295746196 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0043195///terminal bouton GO:0031839///type 1 neuromedin U receptor binding+++GO:0031840///type 2 neuromedin U receptor binding+++GO:0042922///neuromedin U receptor binding "GO:0001659///temperature homeostasis+++GO:0001696///gastric acid secretion+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006940///regulation of smooth muscle contraction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0009648///photoperiodism+++GO:0010460///positive regulation of heart rate+++GO:0019233///sensory perception of pain+++GO:0031652///positive regulation of heat generation+++GO:0042755///eating behavior+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046887///positive regulation of hormone secretion+++GO:0050806///positive regulation of synaptic transmission+++GO:0060259///regulation of feeding behavior+++GO:0060455///negative regulation of gastric acid secretion+++GO:0097009///energy homeostasis+++GO:0120061///negative regulation of gastric emptying+++GO:0120069///positive regulation of stomach fundus smooth muscle contraction+++GO:1902722///positive regulation of prolactin secretion+++GO:1903999///negative regulation of eating behavior+++GO:1904058///positive regulation of sensory perception of pain+++GO:2000252///negative regulation of feeding behavior+++GO:2000821///regulation of grooming behavior" 56187 56187 'Rabggta' mRNA 774.31 806 682.15 18.33 18.75 17.24 18.89 18.84 16.69 18.10666667 18.14 912.74 886.76 787.12 754.1533333 862.2066667 0.095504863 0.182994616 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005968///Rab-protein geranylgeranyltransferase complex GO:0004659///prenyltransferase activity+++GO:0004663///Rab geranylgeranyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008318///protein prenyltransferase activity+++GO:0016740///transferase activity+++GO:0031267///small GTPase binding GO:0018342///protein prenylation+++GO:0018344///protein geranylgeranylation 56188 56188 'Fxyd1' mRNA 3328.33 3380.17 3329.48 455.02 459.14 479.36 200.45 248.08 232.15 464.5066667 226.8933333 1681.18 2002.8 1846.3 3345.993333 1843.426667 1.16E-26 -0.87099757 04024///cAMP signaling pathway "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005901///caveola+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0030315///T-tubule+++GO:0031901///early endosome membrane+++GO:0031965///nuclear membrane+++GO:0042383///sarcolemma+++GO:0042406///extrinsic component of endoplasmic reticulum membrane" GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0017022///myosin binding+++GO:0017080///sodium channel regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0032183///SUMO binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0050897///cobalt ion binding+++GO:0051117///ATPase binding+++GO:0099106///ion channel regulator activity+++GO:0140037///sumo-dependent protein binding "GO:0001666///response to hypoxia+++GO:0001932///regulation of protein phosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006605///protein targeting+++GO:0006606///protein import into nucleus+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007569///cell aging+++GO:0008285///negative regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009411///response to UV+++GO:0010332///response to gamma radiation+++GO:0010522///regulation of calcium ion transport into cytosol+++GO:0010734///negative regulation of protein glutathionylation+++GO:0010761///fibroblast migration+++GO:0016525///negative regulation of angiogenesis+++GO:0016567///protein ubiquitination+++GO:0030099///myeloid cell differentiation+++GO:0030155///regulation of cell adhesion+++GO:0030308///negative regulation of cell growth+++GO:0030578///PML body organization+++GO:0031065///positive regulation of histone deacetylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032692///negative regulation of interleukin-1 production+++GO:0032892///positive regulation of organic acid transport+++GO:0032922///circadian regulation of gene expression+++GO:0032938///negative regulation of translation in response to oxidative stress+++GO:0034097///response to cytokine+++GO:0042752///regulation of circadian rhythm+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043269///regulation of ion transport+++GO:0045087///innate immune response+++GO:0045165///cell fate commitment+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0050821///protein stabilization+++GO:0051457///maintenance of protein location in nucleus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051607///defense response to virus+++GO:0051726///regulation of cell cycle+++GO:0051974///negative regulation of telomerase activity+++GO:0060058///positive regulation of apoptotic process involved in mammary gland involution+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071353///cellular response to interleukin-4+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090398///cellular senescence+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1902187///negative regulation of viral release from host cell+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:1903797///positive regulation of inorganic anion transmembrane transport+++GO:1904816///positive regulation of protein localization to chromosome, telomeric region+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000649///regulation of sodium ion transmembrane transporter activity+++GO:2000779///regulation of double-strand break repair+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway" 56190 56190 'Rbm38' mRNA 122 136 83 3.96 4.34 2.82 8.29 8 8.44 3.706666667 8.243333333 296 277 291 113.6666667 288 2.77E-12 1.336495096 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding "GO:0006397///mRNA processing+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0010830///regulation of myotube differentiation+++GO:0030154///cell differentiation+++GO:0043484///regulation of RNA splicing+++GO:0070935///3'-UTR-mediated mRNA stabilization" 56191 56191 'Tro' mRNA 107 106 116 0.82 0.82 0.96 0.91 1.04 1.13 0.866666667 1.026666667 137 149 161 109.6666667 149 0.071783133 0.429202314 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix+++GO:0097442///CA3 pyramidal cell dendrite+++GO:1990026///hippocampal mossy fiber expansion GO:0003674///molecular_function+++GO:0005178///integrin binding+++GO:0042802///identical protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0002076///osteoblast development+++GO:0007160///cell-matrix adhesion+++GO:0007409///axonogenesis+++GO:0030308///negative regulation of cell growth+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0070593///dendrite self-avoidance+++GO:1905240///negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation+++GO:1990138///neuron projection extension+++GO:2001223///negative regulation of neuron migration 56193 56193 'Plek' mRNA 138 143 136 1.81 1.84 1.89 36.68 37.9 35.85 1.846666667 36.81 3225 3255 3053 139 3177.666667 0 4.503950247 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane "GO:0005080///protein kinase C binding+++GO:0042803///protein homodimerization activity+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002576///platelet degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007229///integrin-mediated signaling pathway+++GO:0010572///positive regulation of platelet activation+++GO:0010920///negative regulation of inositol phosphate biosynthetic process+++GO:0010925///positive regulation of inositol-polyphosphate 5-phosphatase activity+++GO:0030030///cell projection organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030845///phospholipase C-inhibiting G protein-coupled receptor signaling pathway+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031529///ruffle organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0033625///positive regulation of integrin activation+++GO:0035556///intracellular signal transduction+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0046488///phosphatidylinositol metabolic process+++GO:0060305///regulation of cell diameter+++GO:0070493///thrombin-activated receptor signaling pathway+++GO:0070527///platelet aggregation+++GO:0070528///protein kinase C signaling+++GO:0070560///protein secretion by platelet 56194 56194 'Prpf40a' mRNA 1689 1708 1572 14.41 14.36 14.1 16.77 14.71 16.62 14.29 16.03333333 2281 1966 2214 1656.333333 2153.666667 9.94E-07 0.367004581 03040///Spliceosome GO:0005634///nucleus+++GO:0005685///U1 snRNP+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0070064///proline-rich region binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0008380///RNA splicing+++GO:0016477///cell migration+++GO:0032465///regulation of cytokinesis+++GO:0045292///mRNA cis splicing, via spliceosome" 56195 56195 'Ptbp2' mRNA 569 562 555 9.18 8.89 9.52 5.78 6.35 6.22 9.196666667 6.116666667 415 445 430 562 430 0.001036751 -0.397652433 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0030426///growth cone+++GO:0043025///neuronal cell body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0021510///spinal cord development+++GO:0021549///cerebellum development+++GO:0033119///negative regulation of RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:2000177///regulation of neural precursor cell proliferation 56196 56196 'Tdp2' mRNA 408 459 268 11.76 13.04 8.2 9.31 14.26 12.13 11 11.9 371 555 468 378.3333333 464.6666667 0.14449206 0.29876001 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016235///aggresome+++GO:0016604///nuclear body+++GO:0016605///PML body GO:0000287///magnesium ion binding+++GO:0003697///single-stranded DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0036317///tyrosyl-RNA phosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0070260///5'-tyrosyl-DNA phosphodiesterase activity GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048666///neuron development+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 56198 56198 'Heyl' mRNA 3684 3611 3784 43.61 42.04 47.52 11.1 9.88 9.99 44.39 10.32333333 1079 939 941 3693 986.3333333 2.62E-134 -1.919552219 04330///Notch signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05224///Breast cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0050683///AF-1 domain binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003151///outflow tract morphogenesis+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0003203///endocardial cushion morphogenesis+++GO:0003208///cardiac ventricle morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007422///peripheral nervous system development+++GO:0009952///anterior/posterior pattern specification+++GO:0010629///negative regulation of gene expression+++GO:0014031///mesenchymal cell development+++GO:0032835///glomerulus development+++GO:0035914///skeletal muscle cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050767///regulation of neurogenesis+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060412///ventricular septum morphogenesis+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0071773///cellular response to BMP stimulus+++GO:0072014///proximal tubule development" 56199 56199 'Abcb10' mRNA 356 398 317 4.46 4.91 4.21 4.27 4.59 4.17 4.526666667 4.343333333 393 412 371 357 392 0.439230939 0.126771411 02010///ABC transporters GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032592///integral component of mitochondrial membrane "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity" GO:0006783///heme biosynthetic process+++GO:0034514///mitochondrial unfolded protein response+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0048821///erythrocyte development+++GO:0055085///transmembrane transport+++GO:0070455///positive regulation of heme biosynthetic process 56200 56200 'Ddx21' mRNA 386 386 436 4.37 4.29 5.24 6.81 6.64 6.5 4.633333333 6.65 694 662 640 402.6666667 665.3333333 7.40E-09 0.709171193 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0030515///snoRNA binding+++GO:0035198///miRNA binding+++GO:0042802///identical protein binding+++GO:0097322///7SK snRNA binding GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0006364///rRNA processing+++GO:0006366///transcription by RNA polymerase II+++GO:0009615///response to virus+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 56205 56205 'Ensa' mRNA 2460 2513 2654 75.87 77.21 84.56 86.12 78.19 82.6 79.21333333 82.30333333 3486 3048 3148 2542.333333 3227.333333 2.82E-05 0.328777035 GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0019212///phosphatase inhibitor activity+++GO:0019870///potassium channel inhibitor activity+++GO:0019888///protein phosphatase regulator activity+++GO:0051721///protein phosphatase 2A binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0009749///response to glucose+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity+++GO:0050796///regulation of insulin secretion+++GO:0051301///cell division 56207 56207 'Uchl5' mRNA 546 608 579 19.58 22.53 23.18 28.52 29.52 29.24 21.76333333 29.09333333 891 872 889 577.6666667 884 2.84E-09 0.601672016 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031011///Ino80 complex+++GO:0031597///cytosolic proteasome complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070628///proteasome binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:0021670///lateral ventricle development+++GO:0030901///midbrain development+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048853///forebrain morphogenesis+++GO:0061136///regulation of proteasomal protein catabolic process 56208 56208 'Becn1' mRNA 2530.18 2869.29 2713.7 72.78 81.55 82.56 93.82 98.34 94.71 78.96333333 95.62333333 3764.85 3825.09 3666.21 2704.39 3752.05 8.91E-11 0.460318765 04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04215///Apoptosis - multiple species+++04371///Apelin signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection "GO:0000407///phagophore assembly site+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0034271///phosphatidylinositol 3-kinase complex, class III, type I+++GO:0034272///phosphatidylinositol 3-kinase complex, class III, type II+++GO:0035032///phosphatidylinositol 3-kinase complex, class III+++GO:0045335///phagocytic vesicle" GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0051020///GTPase binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0000423///mitophagy+++GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006995///cellular response to nitrogen starvation+++GO:0007040///lysosome organization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0007568///aging+++GO:0008285///negative regulation of cell proliferation+++GO:0010040///response to iron(II) ion+++GO:0010288///response to lead ion+++GO:0010507///negative regulation of autophagy+++GO:0010508///positive regulation of autophagy+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0016236///macroautophagy+++GO:0031667///response to nutrient levels+++GO:0032465///regulation of cytokinesis+++GO:0032801///receptor catabolic process+++GO:0033197///response to vitamin E+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043652///engulfment of apoptotic cell+++GO:0045022///early endosome to late endosome transport+++GO:0045324///late endosome to vacuole transport+++GO:0048666///neuron development+++GO:0050435///amyloid-beta metabolic process+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0051607///defense response to virus+++GO:0051707///response to other organism+++GO:0060548///negative regulation of cell death+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071275///cellular response to aluminum ion+++GO:0071280///cellular response to copper ion+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0098780///response to mitochondrial depolarisation+++GO:1902425///positive regulation of attachment of mitotic spindle microtubules to kinetochore+++GO:1902902///negative regulation of autophagosome assembly+++GO:1905672///negative regulation of lysosome organization+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000786///positive regulation of autophagosome assembly+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 56209 56209 'Gde1' mRNA 2911 3085 2915 112.18 117.25 119.17 120.7 119.09 117.86 116.2 119.2166667 3598 3464 3399 2970.333333 3487 6.38E-04 0.219339671 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0004622///lysophospholipase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008889///glycerophosphodiester phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047395///glycerophosphoinositol glycerophosphodiesterase activity GO:0006580///ethanolamine metabolic process+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0070291///N-acylethanolamine metabolic process 56210 56210 'Rev1' mRNA 608.95 710.45 408.81 7.02 7.95 5.2 3.75 4.48 3.42 6.723333333 3.883333333 390.11 402.58 384.49 576.07 392.3933333 5.67E-04 -0.554641133 03460///Fanconi anemia pathway GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0017125///deoxycytidyl transferase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0042276///error-prone translesion synthesis+++GO:0070987///error-free translesion synthesis+++GO:0071897///DNA biosynthetic process 56212 56212 'Rhog' mRNA 694 670 663 33.39 31.82 33.84 105.36 100.38 109.04 33.01666667 104.9266667 2514 2336 2516 675.6666667 2455.333333 9.71E-128 1.849393123 05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++05135///Yersinia infection GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding "GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0008045///motor neuron axon guidance+++GO:0008360///regulation of cell shape+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043652///engulfment of apoptotic cell+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060326///cell chemotaxis+++GO:0090630///activation of GTPase activity+++GO:1900027///regulation of ruffle assembly+++GO:1902622///regulation of neutrophil migration+++GO:1903078///positive regulation of protein localization to plasma membrane" 56213 56213 'Htra1' mRNA 259 243 242 7.22 6.67 7.15 36.14 34.56 39.99 7.013333333 36.89666667 1491 1392 1597 248 1493.333333 4.68E-136 2.578455456 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019838///growth factor binding+++GO:0042802///identical protein binding GO:0001890///placenta development+++GO:0006508///proteolysis+++GO:0012501///programmed cell death+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050687///negative regulation of defense response to virus+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0097187///dentinogenesis 56214 56214 'Scamp4' mRNA 1742 1965 1886 55.71 61.93 63.99 83.08 84.58 79.73 60.54333333 82.46333333 2986 2967 2773 1864.333333 2908.666667 9.30E-17 0.629023652 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0055038///recycling endosome membrane GO:0003674///molecular_function GO:0015031///protein transport 56215 56215 'Acin1' mRNA 1502.14 1467.2 1170.03 17.21 16.87 14.28 14.02 12.45 14.18 16.12 13.55 1388.56 1216.02 1370.2 1379.79 1324.926667 0.565673726 -0.066837799 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0061574///ASAP complex GO:0003676///nucleic acid binding "GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0030218///erythrocyte differentiation+++GO:0030263///apoptotic chromosome condensation+++GO:0043065///positive regulation of apoptotic process+++GO:0045657///positive regulation of monocyte differentiation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 56216 56216 'Stx1b' mRNA 615.67 592.53 501.04 8.32 8.17 7.37 2.06 2.27 2.38 7.953333333 2.236666667 160 170 161 569.7466667 163.6666667 5.88E-39 -1.806647318 04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle GO:0005634///nucleus+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031201///SNARE complex+++GO:0031594///neuromuscular junction+++GO:0042734///presynaptic membrane+++GO:0048787///presynaptic active zone membrane+++GO:0098793///presynapse+++GO:0099056///integral component of presynaptic membrane GO:0000149///SNARE binding+++GO:0005102///signaling receptor binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding GO:0001956///positive regulation of neurotransmitter secretion+++GO:0006836///neurotransmitter transport+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006906///vesicle fusion+++GO:0010468///regulation of gene expression+++GO:0010807///regulation of synaptic vesicle priming+++GO:0010977///negative regulation of neuron projection development+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0016192///vesicle-mediated transport+++GO:0017157///regulation of exocytosis+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0048278///vesicle docking+++GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0060025///regulation of synaptic activity+++GO:0061025///membrane fusion+++GO:0061669///spontaneous neurotransmitter secretion+++GO:0072657///protein localization to membrane+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:1903422///negative regulation of synaptic vesicle recycling+++GO:1904050///positive regulation of spontaneous neurotransmitter secretion+++GO:1905302///negative regulation of macropinocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential 56217 56217 'Mpp5' mRNA 1147 1364 1111 11.31 13.27 11.61 9.2 8.56 8.9 12.06333333 8.886666667 1077 979 1014 1207.333333 1023.333333 0.009838676 -0.24847474 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0035749///myelin sheath adaxonal region+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043219///lateral loop+++GO:0043220///Schmidt-Lanterman incisure+++GO:0045177///apical part of cell GO:0000166///nucleotide binding+++GO:0004385///guanylate kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019904///protein domain specific binding GO:0002011///morphogenesis of an epithelial sheet+++GO:0007009///plasma membrane organization+++GO:0010467///gene expression+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0021954///central nervous system neuron development+++GO:0021987///cerebral cortex development+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0032288///myelin assembly+++GO:0034613///cellular protein localization+++GO:0035750///protein localization to myelin sheath abaxonal region+++GO:0046037///GMP metabolic process+++GO:0046710///GDP metabolic process+++GO:0072659///protein localization to plasma membrane 56218 56218 'Patz1' mRNA 1593 1566 955 27.83 26.85 17.64 11.03 12.63 11.96 24.10666667 11.87333333 726 812 763 1371.333333 767 9.74E-10 -0.838184225 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0010468///regulation of gene expression+++GO:0010596///negative regulation of endothelial cell migration+++GO:0030217///T cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 56219 56219 'Extl1' mRNA 622 698 633 8.15 9.01 8.8 5.31 6.14 5.41 8.653333333 5.62 466 527 458 651 483.6666667 2.75E-04 -0.438889603 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0050508///glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity" GO:0006486///protein glycosylation 56220 56220 'Zfp386' mRNA 851 810 789 9.9 9.28 9.77 6.16 6.29 6.26 9.65 6.236666667 609 610 598 816.6666667 605.6666667 1.13E-05 -0.44262048 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051038///negative regulation of transcription involved in meiotic cell cycle" 56221 56221 'Ccl24' mRNA 4 2 6 0.2 0.09 0.3 48.42 46.21 44.68 0.196666667 46.43666667 981 948 916 4 948.3333333 1.83E-73 7.877646694 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0031728///CCR3 chemokine receptor binding+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002548///monocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0043547///positive regulation of GTPase activity+++GO:0045766///positive regulation of angiogenesis+++GO:0048245///eosinophil chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:0050729///positive regulation of inflammatory response+++GO:0070098///chemokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071346///cellular response to interferon-gamma+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:2000418///positive regulation of eosinophil migration 56222 56222 'Cited4' mRNA 1663 1676 554 80.46 80.06 28.44 24.83 55.88 47.46 62.98666667 42.72333333 589 1293 1089 1297.666667 990.3333333 0.623330923 -0.371371563 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003713///transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0043627///response to estrogen+++GO:0045893///positive regulation of transcription, DNA-templated" 56223 56223 'Fscn3' mRNA 1 1 2 0.03 0.03 0.07 0.08 0 0 0.043333333 0.026666667 3 0 0 1.333333333 1 0.876979773 -0.468543913 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0031253///cell projection membrane "GO:0003779///actin binding+++GO:0030674///protein binding, bridging+++GO:0051015///actin filament binding" GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007286///spermatid development+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0051017///actin filament bundle assembly 56224 56224 'Tspan5' mRNA 644 645 297 10.49 10.59 4.86 8.66 8.39 11.49 8.646666667 9.513333333 607 602 794 528.6666667 667.6666667 0.425523194 0.342424041 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019899///enzyme binding GO:0045747///positive regulation of Notch signaling pathway+++GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane 56226 56226 'Espn' mRNA 6872 6649 2488 201.52 197.05 87.35 9.44 17.28 14.2 161.9733333 13.64 318 578 498 5336.333333 464.6666667 2.28E-12 -3.50647813 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0031941///filamentous actin+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0051015///actin filament binding GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0030034///microvillar actin bundle assembly+++GO:0030046///parallel actin filament bundle assembly+++GO:0051017///actin filament bundle assembly+++GO:0051491///positive regulation of filopodium assembly+++GO:0051494///negative regulation of cytoskeleton organization+++GO:0051639///actin filament network formation 56228 56228 'Ube2j1' mRNA 1090 1169 1034 16.68 17.67 16.79 21.37 20.21 21.14 17.04666667 20.90666667 1609 1483 1539 1097.666667 1543.666667 8.19E-10 0.481021819 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity "GO:0000209///protein polyubiquitination+++GO:0007286///spermatid development+++GO:0016567///protein ubiquitination+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032680///regulation of tumor necrosis factor production+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 56229 56229 'Thsd1' mRNA 318 277 247 3.07 2.94 2.9 3.63 2.85 2.99 2.97 3.156666667 374.02 298.69 307.09 280.6666667 326.6 0.245395018 0.206540894 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0071944///cell periphery GO:0050840///extracellular matrix binding GO:0002244///hematopoietic progenitor cell differentiation+++GO:0048041///focal adhesion assembly 56233 56233 'Hdac7' mRNA 915 788 562 9.8 8.47 6.24 7.73 7.14 7.32 8.17 7.396666667 850 773 755 755 792.6666667 0.719923727 0.065482711 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0033613///activating transcription factor binding+++GO:0046872///metal ion binding+++GO:0070491///repressing transcription factor binding+++GO:0071889///14-3-3 protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001570///vasculogenesis+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0006954///inflammatory response+++GO:0007043///cell-cell junction assembly+++GO:0007399///nervous system development+++GO:0016575///histone deacetylation+++GO:0030183///B cell differentiation+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042113///B cell activation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070932///histone H3 deacetylation+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1901215///negative regulation of neuron death+++GO:1901223///negative regulation of NIK/NF-kappaB signaling" 56248 56248 'Ak3' mRNA 3512.56 3603.81 3418.75 67.6 68.51 70.35 57.15 55.17 54.95 68.82 55.75666667 3387.55 3193.88 3161.74 3511.706667 3247.723333 0.055336261 -0.124824548 00230///Purine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix "GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016776///phosphotransferase activity, phosphate group as acceptor+++GO:0019205///nucleobase-containing compound kinase activity+++GO:0042802///identical protein binding+++GO:0046899///nucleoside triphosphate adenylate kinase activity" GO:0006139///nucleobase-containing compound metabolic process+++GO:0006172///ADP biosynthetic process+++GO:0006756///AMP phosphorylation+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046033///AMP metabolic process+++GO:0046034///ATP metabolic process+++GO:0046039///GTP metabolic process+++GO:0046041///ITP metabolic process+++GO:0046051///UTP metabolic process+++GO:0046060///dATP metabolic process 56249 56249 'Actr8' mRNA 2184 2279 2277 43.29 44.92 46.26 25.41 29.2 25.37 44.82333333 26.66 1604 1620 1514 2246.666667 1579.333333 1.02E-11 -0.521358362 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005813///centrosome+++GO:0031011///Ino80 complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding "GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0051301///cell division" 56258 56258 'Hnrnph2' mRNA 3272 3474 3376 74.5 77.85 81.52 74.81 73.4 73.6 77.95666667 73.93666667 3782 3616 3603 3374 3667 0.12988748 0.107356907 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0043484///regulation of RNA splicing 56264 56264 'Cpxm1' mRNA 284 326 341 6.55 7.41 8.35 20.53 20.9 20.19 7.436666667 20.54 1023 1017 974 317 1004.666667 2.38E-47 1.650190125 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016485///protein processing 56273 56273 'Pex14' mRNA 1357 1422 1463 39.22 40.49 44.85 25.89 27.12 27.64 41.52 26.88333333 1030 1053 1064 1414 1049 8.40E-07 -0.444067594 04146///Peroxisome GO:0001650///fibrillar center+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:1990429///peroxisomal importomer complex GO:0003714///transcription corepressor activity+++GO:0005102///signaling receptor binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0047485///protein N-terminus binding+++GO:0048487///beta-tubulin binding "GO:0007031///peroxisome organization+++GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix+++GO:0016560///protein import into peroxisome matrix, docking+++GO:0016561///protein import into peroxisome matrix, translocation+++GO:0032091///negative regulation of protein binding+++GO:0034453///microtubule anchoring+++GO:0036250///peroxisome transport along microtubule+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0044721///protein import into peroxisome matrix, substrate release+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0065003///protein-containing complex assembly" 56274 56274 'Stk3' mRNA 1154.79 1280.84 1155.03 21.25 23.11 22.55 15.31 14.34 15.44 22.30333333 15.03 968.83 884.74 941.84 1196.886667 931.8033333 2.53E-05 -0.373360555 04010///MAPK signaling pathway+++04214///Apoptosis - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001841///neural tube formation+++GO:0003157///endocardium development+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032092///positive regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0035329///hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0045600///positive regulation of fat cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0046621///negative regulation of organ growth+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060215///primitive hemopoiesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 56275 56275 'Rbm14' mRNA 1283.65 1293.28 1273.22 22.17 21.98 23.33 18.66 17.9 17.74 22.49333333 18.1 1243.11 1164.53 1144.15 1283.383333 1183.93 0.161606441 -0.128991885 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0016575///histone deacetylation+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046600///negative regulation of centriole replication+++GO:0060395///SMAD protein signal transduction+++GO:0098534///centriole assembly" 56277 56277 'Tmem45a' mRNA 1918 1973 1966 71.53 73.36 78.37 108.09 101.6 106.37 74.42 105.3533333 3232 3003 3111 1952.333333 3115.333333 1.01E-22 0.660991861 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 56278 56278 'Gkap1' mRNA 151 183 176 5.64 6.75 7.24 4.66 5.26 4.98 6.543333333 4.966666667 139 156 145 170 146.6666667 0.343172518 -0.225001537 GO:0005794///Golgi apparatus GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0046628///positive regulation of insulin receptor signaling pathway 56279 56279 'Dipk1b' mRNA 247 284 77 8.9 10.09 2.94 1.22 3.05 2.46 7.31 2.243333333 39 95 76 202.6666667 70 0.028851623 -1.512457656 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 56280 56280 'Mrpl37' mRNA 934 1009 915 36.91 39.33 38.36 41.28 47.98 42.21 38.2 43.82333333 1200 1361 1187 952.6666667 1249.333333 8.04E-05 0.381319399 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 56282 56282 'Mrpl12' mRNA 996 1057 999 65.22 68.46 69.42 75.69 88.33 82.58 67.7 82.2 1325 1507 1397 1017.333333 1409.666667 5.56E-07 0.460127647 03010///Ribosome GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome "GO:0006390///mitochondrial transcription+++GO:0006412///translation+++GO:0045893///positive regulation of transcription, DNA-templated" 56284 56284 'Mrpl19' mRNA 551.94 544.07 545.85 5.88 5.7 6.17 7.32 7.2 7.37 5.916666667 7.296666667 791.45 760.27 772.17 547.2866667 774.63 2.29E-06 0.489827507 03010///Ribosome GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0031965///nuclear membrane GO:0003735///structural constituent of ribosome GO:0006412///translation 56289 56289 'Rassf1' mRNA 715 808 736 23.85 26.5 25.99 39.33 41.18 37.79 25.44666667 39.43333333 1355 1388 1261 753 1334.666667 4.28E-19 0.81463246 04014///Ras signaling pathway+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05219///Bladder cancer+++05223///Non-small cell lung cancer GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0031398///positive regulation of protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071157///negative regulation of cell cycle arrest 56291 56291 'Styx' mRNA 798.7 798.86 723.72 10.08 9.93 9.68 8.35 8.38 8.49 9.896666667 8.406666667 761.13 746.87 750.5 773.76 752.8333333 0.700946066 -0.049472789 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001691///pseudophosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:1990444///F-box domain binding GO:0006470///protein dephosphorylation+++GO:0007283///spermatogenesis+++GO:0016311///dephosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0043086///negative regulation of catalytic activity+++GO:0045204///MAPK export from nucleus+++GO:0062026///negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process+++GO:0070372///regulation of ERK1 and ERK2 cascade 56292 56292 'Naa10' mRNA 634 703 627 38.99 42.97 41.28 40.58 41 36.31 41.08 39.29666667 758 746 654 654.6666667 719.3333333 0.320007446 0.124865612 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031415///NatA complex "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0043022///ribosome binding+++GO:1990189///peptide-serine-N-acetyltransferase activity+++GO:1990190///peptide-glutamate-N-acetyltransferase activity" "GO:0006473///protein acetylation+++GO:0006474///N-terminal protein amino acid acetylation+++GO:0017198///N-terminal peptidyl-serine acetylation+++GO:0018002///N-terminal peptidyl-glutamic acid acetylation+++GO:2000719///negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric" 56293 56293 'Slc35g3' mRNA 0 1 0 0 0.04 0 0 0 0.14 0.013333333 0.046666667 0 0 4 0.333333333 1.333333333 0.644309316 1.890910154 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 56294 56294 'Ptpn9' mRNA 754 824 346 10.02 10.78 4.88 4.86 5.26 6.42 8.56 5.513333333 421 445 538 641.3333333 468 0.300529336 -0.447096958 GO:0005737///cytoplasm+++GO:0044306///neuron projection terminus GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0010977///negative regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:1903078///positive regulation of protein localization to plasma membrane 56295 56295 'Higd1a' mRNA 1563 1647 1736 54.35 56.4 63.97 52.2 58.38 53.65 58.24 54.74333333 1727 1887 1717 1648.666667 1777 0.379782823 0.094619067 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0042149///cellular response to glucose starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097250///mitochondrial respiratory chain supercomplex assembly 56296 56296 'Dmrtb1' mRNA 69 60 86 2.65 2.31 3.65 0.04 0.11 0.22 2.87 0.123333333 1 3 7 71.66666667 3.666666667 4.78E-13 -4.306611243 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007281///germ cell development+++GO:0007548///sex differentiation" 56297 56297 'Arl6' mRNA 1089 1104 1262 40.93 40.92 50.56 23.84 23.19 22.51 44.13666667 23.18 708 668 644 1151.666667 673.3333333 2.96E-13 -0.790901389 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005879///axonemal microtubule+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0005543///phospholipid binding+++GO:0046872///metal ion binding GO:0006471///protein ADP-ribosylation+++GO:0006612///protein targeting to membrane+++GO:0006886///intracellular protein transport+++GO:0007265///Ras protein signal transduction+++GO:0007420///brain development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010842///retina layer formation+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0016192///vesicle-mediated transport+++GO:0030030///cell projection organization+++GO:0045444///fat cell differentiation+++GO:0051258///protein polymerization+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:0097499///protein localization to non-motile cilium+++GO:1903441///protein localization to ciliary membrane+++GO:1903445///protein transport from ciliary membrane to plasma membrane 56298 56298 'Atl2' mRNA 613 715 626 8.95 10.16 9.52 9.79 9.64 10.07 9.543333333 9.833333333 780 741 766 651.3333333 762.3333333 0.051645199 0.216040963 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098826///endoplasmic reticulum tubular network membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0051260///protein homooligomerization+++GO:1990809///endoplasmic reticulum tubular network membrane organization 56299 56299 'Fkbpl' mRNA 219 244 264 7.41 8.14 9.48 6.51 7.34 5.88 8.343333333 6.576666667 221 243 193 242.3333333 219 0.464551436 -0.160565998 GO:0005576///extracellular region GO:0045765///regulation of angiogenesis+++GO:1905553///regulation of blood vessel branching 56305 56305 'Pitpnb' mRNA 2403 2638 2666 48.01 51.9 56.53 38.14 37.49 36.27 52.14666667 37.3 2204 2118 2031 2569 2117.666667 3.10E-04 -0.292857898 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0005543///phospholipid binding+++GO:0005548///phospholipid transporter activity+++GO:0008289///lipid binding+++GO:0008525///phosphatidylcholine transporter activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0031210///phosphatidylcholine binding+++GO:0035091///phosphatidylinositol binding+++GO:0120019///intermembrane phosphotidylcholine transfer activity "GO:0001701///in utero embryonic development+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer" 56306 56306 'Sinhcaf' mRNA 727 746 627 14.84 14.88 13.53 12.47 11.28 13.32 14.41666667 12.35666667 697 621 720 700 679.3333333 0.715114056 -0.052776933 GO:0005634///nucleus+++GO:0016580///Sin3 complex GO:0005515///protein binding GO:0008284///positive regulation of cell proliferation+++GO:0030336///negative regulation of cell migration+++GO:0045596///negative regulation of cell differentiation 56307 56307 'Metap2' mRNA 2188.89 2260.17 2243.34 44.15 45.45 48.4 60.86 59.76 60.01 46 60.21 3332.24 3175.8 3196.4 2230.8 3234.813333 2.42E-15 0.523236077 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0004177///aminopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0018206///peptidyl-methionine modification+++GO:0031365///N-terminal protein amino acid modification+++GO:0070084///protein initiator methionine removal 56309 56309 'Mycbp' mRNA 628 639 681 25.03 25.12 28.79 17.17 16.57 16.28 26.31333333 16.67333333 495 466 454 649.3333333 471.6666667 6.11E-05 -0.475756136 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003713///transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 56310 56310 'Gps2' mRNA 942.51 937.76 523.83 42.58 42.14 26.86 23.84 31.31 28.81 37.19333333 27.98666667 573.58 745.17 683.11 801.3666667 667.2866667 0.438294356 -0.25960528 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0017053///transcriptional repressor complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0030332///cyclin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0019216///regulation of lipid metabolic process+++GO:0030183///B cell differentiation+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0045598///regulation of fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046329///negative regulation of JNK cascade+++GO:0050728///negative regulation of inflammatory response+++GO:0050859///negative regulation of B cell receptor signaling pathway+++GO:0098780///response to mitochondrial depolarisation+++GO:1900045///negative regulation of protein K63-linked ubiquitination 56312 56312 'Nupr1' mRNA 3047 2809 2834 364.75 334.56 360.1 435.11 480.97 411.54 353.1366667 442.54 4149 4459 3783 2896.666667 4130.333333 8.86E-11 0.500312457 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032993///protein-DNA complex+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0010698///acetyltransferase activator activity "GO:0002526///acute inflammatory response+++GO:0006473///protein acetylation+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0009636///response to toxic substance+++GO:0010506///regulation of autophagy+++GO:0010507///negative regulation of autophagy+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0031401///positive regulation of protein modification process+++GO:0035914///skeletal muscle cell differentiation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045786///negative regulation of cell cycle+++GO:0045787///positive regulation of cell cycle+++GO:0045820///negative regulation of glycolytic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050790///regulation of catalytic activity+++GO:0065003///protein-containing complex assembly+++GO:0150078///positive regulation of neuroinflammatory response+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1902902///negative regulation of autophagosome assembly+++GO:1903862///positive regulation of oxidative phosphorylation+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:1904691///negative regulation of type B pancreatic cell proliferation+++GO:1905897///regulation of response to endoplasmic reticulum stress+++GO:2000194///regulation of female gonad development+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 56314 56314 'Zfp113' mRNA 727.2 813.83 682.78 6.39 7.3 6.8 3.58 4.1 3.04 6.83 3.573333333 477.6 518.7 397.74 741.27 464.68 3.28E-08 -0.683716101 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 56316 56316 'Ggcx' mRNA 1164.88 1115 968.71 19.24 18.23 17.28 17.53 18.61 17.74 18.25 17.96 1198.63 1255.69 1187.05 1082.863333 1213.79 0.105339366 0.156236873 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008488///gamma-glutamyl carboxylase activity+++GO:0016829///lyase activity+++GO:0019842///vitamin binding GO:0017187///peptidyl-glutamic acid carboxylation 56317 56317 'Anapc7' mRNA 892 933 960 17.93 18.45 20.46 17.69 16.83 18.09 18.94666667 17.53666667 1013 941 1003 928.3333333 985.6666667 0.544565096 0.0725349 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0019903///protein phosphatase binding GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 56318 56318 'Acpp' mRNA 31 36 42 0.37 0.42 0.55 1.76 1.84 1.66 0.446666667 1.753333333 146 151 131 36.33333333 142.6666667 1.86E-12 1.958323186 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0030175///filopodium+++GO:0031985///Golgi cisterna+++GO:0045177///apical part of cell GO:0003993///acid phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033265///choline binding+++GO:0042131///thiamine phosphate phosphatase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0052642///lysophosphatidic acid phosphatase activity GO:0006144///purine nucleobase metabolic process+++GO:0006772///thiamine metabolic process+++GO:0007040///lysosome organization+++GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046085///adenosine metabolic process+++GO:0051930///regulation of sensory perception of pain+++GO:0060168///positive regulation of adenosine receptor signaling pathway 56320 56320 'Dbn1' mRNA 486 433 458 9.2 8.07 9.19 13.3 12.41 13 8.82 12.90333333 809 737 765 459 770.3333333 2.21E-11 0.733761638 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005921///gap junction+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030427///site of polarized growth+++GO:0030864///cortical actin cytoskeleton+++GO:0032279///asymmetric synapse+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0044295///axonal growth cone+++GO:0044308///axonal spine+++GO:0044309///neuron spine+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol+++GO:1902737///dendritic filopodium GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005522///profilin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding GO:0001701///in utero embryonic development+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010643///cell communication by chemical coupling+++GO:0010644///cell communication by electrical coupling+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0030154///cell differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:0031915///positive regulation of synaptic plasticity+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0032507///maintenance of protein location in cell+++GO:0045773///positive regulation of axon extension+++GO:0048699///generation of neurons+++GO:0048812///neuron projection morphogenesis+++GO:0051220///cytoplasmic sequestering of protein+++GO:0051489///regulation of filopodium assembly+++GO:0060134///prepulse inhibition+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061351///neural precursor cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090327///negative regulation of locomotion involved in locomotory behavior+++GO:0098828///modulation of inhibitory postsynaptic potential+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0120080///negative regulation of microfilament motor activity+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902685///positive regulation of receptor localization to synapse+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:1904113///negative regulation of muscle filament sliding+++GO:1904622///negative regulation of actin-dependent ATPase activity+++GO:2000463///positive regulation of excitatory postsynaptic potential 56321 56321 'Aatf' mRNA 479 472 510 15.36 14.96 17.35 14.8 15.76 17.12 15.89 15.89333333 530 551 590 487 557 0.191935869 0.180388292 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0043522///leucine zipper domain binding+++GO:0048156///tau protein binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007155///cell adhesion+++GO:0007346///regulation of mitotic cell cycle+++GO:0032929///negative regulation of superoxide anion generation+++GO:0040016///embryonic cleavage+++GO:0042254///ribosome biogenesis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2001234///negative regulation of apoptotic signaling pathway" 56322 56322 'Timm22' mRNA 1049 1095 1088 20.46 21 22.52 19.94 21.17 20.33 21.32666667 20.48 1174 1217 1161 1077.333333 1184 0.217111385 0.123905306 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042721///TIM22 mitochondrial import inner membrane insertion complex GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0071806///protein transmembrane transport 56323 56323 'Dnajb5' mRNA 92 102 54 1.56 1.76 1.04 1.84 1.77 2.37 1.453333333 1.993333333 121 112 154 82.66666667 129 0.026873062 0.640972478 GO:0005634///nucleus+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0051085///chaperone cofactor-dependent protein refolding 56324 56324 'Stam2' mRNA 746 842 870 9.85 11.03 12.17 12.94 12.43 12.03 11.01666667 12.46666667 1117 1060 1006 819.3333333 1061 7.86E-04 0.358151881 04144///Endocytosis+++04630///JAK-STAT signaling pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0015031///protein transport 56325 56325 'Abcb9' mRNA 636 608 631 11.17 10.19 11.68 5.85 5.8 6.01 11.01333333 5.886666667 387 377 404 625 389.3333333 3.47E-09 -0.695769752 02010///ABC transporters+++04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0042824///MHC class I peptide loading complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015421///oligopeptide-transporting ATPase activity+++GO:0015433///peptide antigen-transporting ATPase activity+++GO:0015440///peptide-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0042288///MHC class I protein binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0046978///TAP1 binding" GO:0006518///peptide metabolic process+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0035672///oligopeptide transmembrane transport+++GO:0055085///transmembrane transport 56327 56327 'Arl2' mRNA 2115 2112 2055 161.59 159.8 166.61 131.88 132.57 120.93 162.6666667 128.46 1977 1936 1751 2094 1888 0.045120398 -0.161618822 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0015630///microtubule cytoskeleton+++GO:0016328///lateral plasma membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006110///regulation of glycolytic process+++GO:0006457///protein folding+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0015870///acetylcholine transport+++GO:0031113///regulation of microtubule polymerization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0034260///negative regulation of GTPase activity+++GO:0051457///maintenance of protein location in nucleus+++GO:0070830///bicellular tight junction assembly+++GO:1903715///regulation of aerobic respiration 56330 56330 'Pdcd5' mRNA 951 1038 1023 109.67 118.99 125.16 119.07 134.99 131.58 117.94 128.5466667 1180 1301 1257 1004 1246 0.002288306 0.299682397 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0008201///heparin binding+++GO:0010698///acetyltransferase activator activity+++GO:0048487///beta-tubulin binding GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1903638///positive regulation of protein import into mitochondrial outer membrane+++GO:1903645///negative regulation of chaperone-mediated protein folding 56332 56332 'Amotl2' mRNA 2353 2528 2277 30.18 31.87 30.99 21.96 19.92 21.74 31.01333333 21.20666667 1969 1748 1889 2386 1868.666667 2.47E-07 -0.364165014 04530///Tight junction GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0003365///establishment of cell polarity involved in ameboidal cell migration+++GO:0016055///Wnt signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0035329///hippo signaling 56334 56334 'Tmed2' mRNA 6817 6898 6695 196.22 195.6 204.65 255.25 275.93 262.38 198.8233333 264.52 10195 10758 10139 6803.333333 10364 2.64E-25 0.59581306 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030137///COPI-coated vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042589///zymogen granule membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0001892///embryonic placenta development+++GO:0001893///maternal placenta development+++GO:0001947///heart looping+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0008104///protein localization+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032525///somite rostral/caudal axis specification+++GO:0034260///negative regulation of GTPase activity+++GO:0035264///multicellular organism growth+++GO:0036342///post-anal tail morphogenesis+++GO:0036499///PERK-mediated unfolded protein response+++GO:0048598///embryonic morphogenesis+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0060716///labyrinthine layer blood vessel development+++GO:0060717///chorion development+++GO:0072659///protein localization to plasma membrane+++GO:0090158///endoplasmic reticulum membrane organization+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:1905069///allantois development+++GO:2000638///regulation of SREBP signaling pathway 56335 56335 'Mettl3' mRNA 543.12 607.23 608.29 15.29 16.83 18.16 12.73 12.43 13.19 16.76 12.78333333 519.99 495.99 521.81 586.2133333 512.5966667 0.104877865 -0.209281928 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0001734///mRNA (N6-adenosine)-methyltransferase activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016422///mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046982///protein heterodimerization activity+++GO:1904047///S-adenosyl-L-methionine binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0001510///RNA methylation+++GO:0002376///immune system process+++GO:0006382///adenosine to inosine editing+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007623///circadian rhythm+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0016556///mRNA modification+++GO:0019827///stem cell population maintenance+++GO:0021861///forebrain radial glial cell differentiation+++GO:0030154///cell differentiation+++GO:0031053///primary miRNA processing+++GO:0032259///methylation+++GO:0034644///cellular response to UV+++GO:0042063///gliogenesis+++GO:0045087///innate immune response+++GO:0045580///regulation of T cell differentiation+++GO:0045727///positive regulation of translation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0048477///oogenesis+++GO:0048511///rhythmic process+++GO:0051445///regulation of meiotic cell cycle+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061157///mRNA destabilization+++GO:0080009///mRNA methylation+++GO:0098508///endothelial to hematopoietic transition+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:1903679///positive regulation of cap-independent translational initiation+++GO:1990744///primary miRNA methylation" 56336 56336 'B4galt5' mRNA 911 846 595 11.67 10.65 8.08 10.17 8.99 9.79 10.13333333 9.65 914 789 852 784 851.6666667 0.452338514 0.114059088 00512///Mucin type O-glycan biosynthesis GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003945///N-acetyllactosamine synthase activity+++GO:0008378///galactosyltransferase activity+++GO:0008489///UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0009101///glycoprotein biosynthetic process+++GO:0010706///ganglioside biosynthetic process via lactosylceramide+++GO:0021955///central nervous system neuron axonogenesis+++GO:0022010///central nervous system myelination+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0031647///regulation of protein stability+++GO:0040019///positive regulation of embryonic development+++GO:0042551///neuron maturation+++GO:0070085///glycosylation 56338 56338 'Txnip' mRNA 7888 7790 7286 155.55 151.19 152.42 170.43 150.84 163.88 153.0533333 161.7166667 9943 8594 9257 7654.666667 9264.666667 4.19E-06 0.2632255 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006979///response to oxidative stress+++GO:0007049///cell cycle+++GO:0009612///response to mechanical stimulus+++GO:0009749///response to glucose+++GO:0015031///protein transport+++GO:0030216///keratinocyte differentiation+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0042127///regulation of cell proliferation+++GO:0042493///response to drug+++GO:0042542///response to hydrogen peroxide+++GO:0043065///positive regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0051592///response to calcium ion+++GO:0051782///negative regulation of cell division+++GO:0071228///cellular response to tumor cell 56347 56347 'Eif3c' mRNA 2705 2961 2923 51.71 55.7 59.27 63.8 60.03 63.31 55.56 62.38 3840 3529 3690 2863 3686.333333 7.66E-07 0.350909692 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0031369///translation initiation factor binding+++GO:0043022///ribosome binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0045727///positive regulation of translation+++GO:1902416///positive regulation of mRNA binding 56348 56348 'Hsd17b12' mRNA 1841 1770 1924 57.55 54.52 63.8 67.61 60.46 65.62 58.62333333 64.56333333 2486 2170 2335 1845 2330.333333 1.25E-04 0.321554185 00062///Fatty acid elongation+++00140///Steroid hormone biosynthesis+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0009923///fatty acid elongase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix GO:0001968///fibronectin binding+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0016491///oxidoreductase activity+++GO:0016509///long-chain-3-hydroxyacyl-CoA dehydrogenase activity+++GO:0044594///17-beta-hydroxysteroid dehydrogenase (NAD+) activity+++GO:0050062///long-chain-fatty-acyl-CoA reductase activity+++GO:0072582///17-beta-hydroxysteroid dehydrogenase (NADP+) activity+++GO:0102339///3-oxo-arachidoyl-CoA reductase activity+++GO:0102340///3-oxo-behenoyl-CoA reductase activity+++GO:0102341///3-oxo-lignoceroyl-CoA reductase activity+++GO:0102342///3-oxo-cerotoyl-CoA reductase activity GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006694///steroid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization 56349 56349 'Net1' mRNA 989 1000 982 15.99 15.78 16.83 10.67 8.9 9.02 16.2 9.53 769 614 619 990.3333333 667.3333333 3.47E-08 -0.583758076 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051451///myoblast migration+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071479///cellular response to ionizing radiation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading 56350 56350 'Arl3' mRNA 1270 1267 1115 90.29 89.17 84.13 62.54 58.91 62.35 87.86333333 61.26666667 1008 925 971 1217.333333 968 6.79E-05 -0.340873704 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0019003///GDP binding+++GO:0032794///GTPase activating protein binding+++GO:0046872///metal ion binding GO:0000281///mitotic cytokinesis+++GO:0001822///kidney development+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0007049///cell cycle+++GO:0007224///smoothened signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0031116///positive regulation of microtubule polymerization+++GO:0042073///intraciliary transport+++GO:0042461///photoreceptor cell development+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1903441///protein localization to ciliary membrane 56351 56351 'Ptges3' mRNA 3625.77 3578.61 3418.73 105.92 103 105.95 108.31 100.05 106.16 104.9566667 104.84 4262.3 3843.5 4043.4 3541.036667 4049.733333 0.003489555 0.181594018 00590///Arachidonic acid metabolism+++05207///Chemical carcinogenesis - receptor activation GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0101031///chaperone complex GO:0002039///p53 binding+++GO:0003720///telomerase activity+++GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004667///prostaglandin-D synthase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding+++GO:0043295///glutathione binding+++GO:0050220///prostaglandin-E synthase activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0070182///DNA polymerase binding GO:0001516///prostaglandin biosynthetic process+++GO:0002526///acute inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0005978///glycogen biosynthetic process+++GO:0006457///protein folding+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0007004///telomere maintenance via telomerase+++GO:0008283///cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0014070///response to organic cyclic compound+++GO:0019233///sensory perception of pain+++GO:0031620///regulation of fever generation+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0034097///response to cytokine+++GO:0042327///positive regulation of phosphorylation+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0043588///skin development+++GO:0050727///regulation of inflammatory response+++GO:0050821///protein stabilization+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051592///response to calcium ion+++GO:0051973///positive regulation of telomerase activity+++GO:0060430///lung saccule development+++GO:0060548///negative regulation of cell death+++GO:0098869///cellular oxidant detoxification+++GO:1905323///telomerase holoenzyme complex assembly 56353 56353 'Rybp' mRNA 261.32 297.35 270.29 3.21 3.59 3.52 3.37 2.43 3.28 3.44 3.026666667 315.84 222.07 297.81 276.32 278.5733333 0.995389082 -0.003355326 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031519///PcG protein complex GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035518///histone H2A monoubiquitination+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated" 56354 56354 'Dnajc7' mRNA 2632.99 2641.69 2643.9 85.58 84.15 91.19 68.57 65.73 65.12 86.97333333 66.47333333 2447.67 2304.47 2239.35 2639.526667 2330.496667 0.008142599 -0.192667914 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0031072///heat shock protein binding GO:0051085///chaperone cofactor-dependent protein refolding 56356 56356 'Gltp' mRNA 3231 3241 2669 116.46 115.19 102.06 97.28 107.3 106.71 111.2366667 103.7633333 3101 3338 3291 3047 3243.333333 0.33529879 0.082937129 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0051861///glycolipid binding+++GO:0120013///intermembrane lipid transfer activity+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0006869///lipid transport+++GO:0035627///ceramide transport+++GO:0120009///intermembrane lipid transfer+++GO:1902389///ceramide 1-phosphate transport 56357 56357 'Ivd' mRNA 2711 2679 2499 40.61 39.47 39.7 33.88 34.41 31.96 39.92666667 33.41666667 2603 2583 2378 2629.666667 2521.333333 0.370226744 -0.071661419 "00280///Valine, leucine and isoleucine degradation" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0031966///mitochondrial membrane "GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004085///butyryl-CoA dehydrogenase activity+++GO:0008470///isovaleryl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding" GO:0006552///leucine catabolic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase 56358 56358 'Copz2' mRNA 626 606 209 43.85 42 15.53 18.95 40.77 35.93 33.79333333 31.88333333 310 650 568 480.3333333 509.3333333 0.889985947 0.102051995 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport" 56360 56360 'Acot9' mRNA 284 311 307 9.35 10.11 10.75 27.77 31.99 28.94 10.07 29.56666667 966 1063 966 300.6666667 998.3333333 2.12E-52 1.719787572 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003986///acetyl-CoA hydrolase activity+++GO:0005515///protein binding+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0046459///short-chain fatty acid metabolic process 56361 56361 'Pus1' mRNA 326 265 197 11.89 9.46 7.86 13.37 12.93 12.74 9.736666667 13.01333333 413 409 383 262.6666667 401.6666667 3.19E-04 0.607729429 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005739///mitochondrion GO:0000049///tRNA binding+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0106029///tRNA pseudouridine synthase activity GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0031119///tRNA pseudouridine synthesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990481///mRNA pseudouridine synthesis 56363 56363 'Tmeff2' mRNA 172 217 171 2.81 3.47 2.91 3.82 3.46 3.59 3.063333333 3.623333333 269 240 246 186.6666667 251.6666667 0.02110546 0.421054966 GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016477///cell migration+++GO:0030336///negative regulation of cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0044319///wound healing, spreading of cells+++GO:0045720///negative regulation of integrin biosynthetic process+++GO:0051497///negative regulation of stress fiber assembly" 56364 56364 'Zmym3' mRNA 1168 1297 1079 12.77 14.5 12.64 9.2 7.74 8.56 13.30333333 8.5 796 696 735 1181.333333 742.3333333 1.32E-13 -0.680470675 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis 56365 56365 'Clcnkb' mRNA 33 37 17 0.84 0.88 0.44 0.92 0.95 1.03 0.72 0.966666667 44 38 48 29 43.33333333 0.230502694 0.579059998 04966///Collecting duct acid secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0055085///transmembrane transport 56367 56367 'Scoc' mRNA 1381.03 1543.94 1596.04 41.88 46.08 51.45 43.51 44.32 47.46 46.47 45.09666667 1680.94 1674.94 1786.99 1507.003333 1714.29 0.086291277 0.171303849 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003674///molecular_function GO:0016239///positive regulation of macroautophagy+++GO:0061635///regulation of protein complex stability 56368 56368 'Cyb561d2' mRNA 1617 1621 1509 85.36 85.27 83.97 33.58 35.16 34.34 84.86666667 34.36 737 741 726 1582.333333 734.6666667 9.11E-44 -1.117724623 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle GO:0004322///ferroxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0055085///transmembrane transport 56369 56369 'Apip' mRNA 427 438 444 30.34 30.75 33.41 34.77 35.21 39.26 31.5 36.41333333 562 555 613 436.3333333 576.6666667 0.001590361 0.389701986 00270///Cysteine and methionine metabolism GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0046570///methylthioribulose 1-phosphate dehydratase activity+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0019284///L-methionine salvage from S-adenosylmethionine+++GO:0019509///L-methionine salvage from methylthioadenosine+++GO:0043066///negative regulation of apoptotic process+++GO:0051289///protein homotetramerization+++GO:0070269///pyroptosis+++GO:0070372///regulation of ERK1 and ERK2 cascade 56370 56370 'Tagln3' mRNA 13 4 10 0.69 0.21 0.56 0.6 0.62 0.77 0.486666667 0.663333333 13 13 16 9 14 0.493384528 0.620025681 GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0043209///myelin sheath GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 56371 56371 'Fzr1' mRNA 1473 1368 468 36.75 33.61 12.39 10.81 29.2 22.93 27.58333333 20.98 498 1314 1023 1103 945 0.82203382 -0.203271733 04110///Cell cycle+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0016600///flotillin complex+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030864///cortical actin cytoskeleton+++GO:0031965///nuclear membrane+++GO:0033268///node of Ranvier+++GO:0043219///lateral loop+++GO:0043220///Schmidt-Lanterman incisure+++GO:0043296///apical junction complex+++GO:0043679///axon terminus+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008092///cytoskeletal protein binding+++GO:0010997///anaphase-promoting complex binding+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0030506///ankyrin binding+++GO:0032794///GTPase activating protein binding+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0045295///gamma-catenin binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:1990757///ubiquitin ligase activator activity "GO:0001701///in utero embryonic development+++GO:0001829///trophectodermal cell differentiation+++GO:0003382///epithelial cell morphogenesis+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0007566///embryo implantation+++GO:0007605///sensory perception of sound+++GO:0008284///positive regulation of cell proliferation+++GO:0009636///response to toxic substance+++GO:0010033///response to organic substance+++GO:0010468///regulation of gene expression+++GO:0010955///negative regulation of protein processing+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016567///protein ubiquitination+++GO:0019538///protein metabolic process+++GO:0021983///pituitary gland development+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031175///neuron projection development+++GO:0031532///actin cytoskeleton reorganization+++GO:0032880///regulation of protein localization+++GO:0033561///regulation of water loss via skin+++GO:0034332///adherens junction organization+++GO:0035847///uterine epithelium development+++GO:0040020///regulation of meiotic nuclear division+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042493///response to drug+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0045732///positive regulation of protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046697///decidualization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051301///cell division+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060576///intestinal epithelial cell development+++GO:0060662///salivary gland cavitation+++GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0070306///lens fiber cell differentiation+++GO:0070830///bicellular tight junction assembly+++GO:0071230///cellular response to amino acid stimulus+++GO:0071285///cellular response to lithium ion+++GO:0071681///cellular response to indole-3-methanol+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090102///cochlea development+++GO:0090344///negative regulation of cell aging+++GO:0098609///cell-cell adhesion+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:1905786///positive regulation of anaphase-promoting complex-dependent catabolic process+++GO:2000008///regulation of protein localization to cell surface+++GO:2001222///regulation of neuron migration" 56372 56372 '1110004F10Rik' mRNA 2586 2681 2607 108.23 110.83 115.88 101.11 112.65 101.06 111.6466667 104.94 2778 3019 2678 2624.666667 2825 0.275763578 0.094600541 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 56373 56373 'Cpb2' mRNA 1 0 0 0.04 0 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04610///Complement and coagulation cascades+++04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0009408///response to heat+++GO:0010757///negative regulation of plasminogen activation+++GO:0042493///response to drug+++GO:0042730///fibrinolysis+++GO:0051918///negative regulation of fibrinolysis+++GO:0071333///cellular response to glucose stimulus+++GO:0097421///liver regeneration+++GO:2000346///negative regulation of hepatocyte proliferation 56374 56374 'Tmem59' mRNA 14786 15488 14775 563.45 582.05 597.32 448.7 463.5 445.27 580.94 452.49 13527 13635 12987 15016.33333 13383 0.001271448 -0.177986382 GO:0000137///Golgi cis cisterna+++GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane GO:0004175///endopeptidase activity GO:0006508///proteolysis+++GO:0006914///autophagy+++GO:0010508///positive regulation of autophagy+++GO:0010955///negative regulation of protein processing+++GO:0090285///negative regulation of protein glycosylation in Golgi+++GO:1903077///negative regulation of protein localization to plasma membrane 56375 56375 'B4galt4' mRNA 2670 2631 2610 71.54 69.91 73.52 63.2 63 61.66 71.65666667 62.62 2689 2605 2547 2637 2613.666667 0.783577126 -0.025313574 00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003945///N-acetyllactosamine synthase activity+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0070085///glycosylation 56376 56376 'Pdlim5' mRNA 1275 1457 1308 14.81 16.65 16.28 19.78 17.95 19.11 15.91333333 18.94666667 1964 1744 1821 1346.666667 1843 4.50E-08 0.440592293 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051371///muscle alpha-actinin binding GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0051963///regulation of synapse assembly+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0061061///muscle structure development 56378 56378 'Arpc3' mRNA 332 299 224 24.21 21.59 17.33 49.14 53.31 69.13 21.04333333 57.19333333 772 816 1049 285 879 4.10E-28 1.620358787 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0061850///growth cone leading edge GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:1990090///cellular response to nerve growth factor stimulus 56379 56379 'Kcnj1' mRNA 2 1 0 0.04 0.02 0 0 0 0 0.02 0 0 0 0 1 0 0.614783931 -2.421998967 04960///Aldosterone-regulated sodium reabsorption+++04971///Gastric acid secretion GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005524///ATP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0015272///ATP-activated inward rectifier potassium channel activity+++GO:0030955///potassium ion binding+++GO:0042277///peptide binding" GO:0001822///kidney development+++GO:0001894///tissue homeostasis+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0009791///post-embryonic development+++GO:0010467///gene expression+++GO:0034765///regulation of ion transmembrane transport+++GO:0043066///negative regulation of apoptotic process+++GO:0070294///renal sodium ion absorption+++GO:0071286///cellular response to magnesium ion+++GO:0072359///circulatory system development+++GO:1900128///regulation of G-protein activated inward rectifier potassium channel activity+++GO:1990573///potassium ion import across plasma membrane 56380 56380 'Arid3b' mRNA 867 1078 921 13.13 15.84 14.46 3.52 3.62 2.82 14.47666667 3.32 264 265 219 955.3333333 249.3333333 3.48E-55 -1.948774902 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II 56381 56381 'Spen' mRNA 1053 957 845 4.41 3.97 3.79 2.95 2.54 2.81 4.056666667 2.766666667 810 678 749 951.6666667 745.6666667 5.86E-04 -0.362219796 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050769///positive regulation of neurogenesis" 56382 56382 'Rab9' mRNA 748 720 703 36.98 34.58 35.92 32.72 32.3 32.82 35.82666667 32.61333333 761 732 755 723.6666667 749.3333333 0.77544629 0.038525726 05132///Salmonella infection+++05162///Measles GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0042802///identical protein binding "GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0032880///regulation of protein localization+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045921///positive regulation of exocytosis+++GO:0052403///negative regulation by host of symbiont catalytic activity+++GO:0052405///negative regulation by host of symbiont molecular function" 56384 56384 'Letm1' mRNA 1741 1990 2014 17.96 20.19 22.04 21.83 21.58 20.98 20.06333333 21.46333333 2436 2353 2268 1915 2352.333333 0.001308695 0.282349108 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0015369///calcium:proton antiporter activity+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0006875///cellular metal ion homeostasis+++GO:0034214///protein hexamerization+++GO:0042407///cristae formation+++GO:0051260///protein homooligomerization+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0099093///calcium export from the mitochondrion+++GO:1900069///regulation of cellular hyperosmotic salinity response 56386 56386 'B4galt6' mRNA 521.98 468.98 387.94 5.32 4.68 4.29 6.1 5.15 5.63 4.763333333 5.626666667 683.11 564.1 622.86 459.6333333 623.3566667 7.64E-04 0.432607473 00600///Sphingolipid metabolism GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008378///galactosyltransferase activity+++GO:0008489///UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0001572///lactosylceramide biosynthetic process+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0010706///ganglioside biosynthetic process via lactosylceramide+++GO:0021955///central nervous system neuron axonogenesis+++GO:0022010///central nervous system myelination+++GO:0030148///sphingolipid biosynthetic process+++GO:0042551///neuron maturation+++GO:0070085///glycosylation 56389 56389 'Stx5a' mRNA 1641 1786 1738 48 51.92 53.87 44.77 48.42 48.12 51.26333333 47.10333333 1732 1835 1815 1721.666667 1794 0.658581865 0.047417817 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0031982///vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0047485///protein N-terminus binding "GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006906///vesicle fusion+++GO:0016192///vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045732///positive regulation of protein catabolic process+++GO:0048278///vesicle docking+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0061025///membrane fusion+++GO:0090166///Golgi disassembly+++GO:1903358///regulation of Golgi organization" 56390 56390 'Znrd2' mRNA 455 465 456 46.36 47.05 49.31 41.45 44.89 47.12 47.57333333 44.48666667 465 490 510 458.6666667 488.3333333 0.613811745 0.078953639 GO:0005575///cellular_component GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0008150///biological_process 56392 56392 'Shoc2' mRNA 1014 1086 975.37 12.28 12.98 12.63 13.23 13.05 13.15 12.63 13.14333333 1215.39 1175 1166 1025.123333 1185.463333 0.02439181 0.198835114 04014///Ras signaling pathway GO:0000164///protein phosphatase type 1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008157///protein phosphatase 1 binding+++GO:0019903///protein phosphatase binding GO:0007165///signal transduction+++GO:0046579///positive regulation of Ras protein signal transduction 56395 56395 'Tmem115' mRNA 1436 1477 1451 37.22 37.71 39.9 30.68 32.81 31.56 38.27666667 31.68333333 1361 1421 1355 1454.666667 1379 0.354668686 -0.088968069 GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017119///Golgi transport complex+++GO:0032580///Golgi cisterna membrane GO:0042802///identical protein binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER" 56397 56397 'Morf4l2' mRNA 2721 2767 2604 83.56 83.75 85.32 136.32 134.23 130.99 84.21 133.8466667 5098 4897 4739 2697.333333 4911.333333 6.83E-50 0.852963453 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0035267///NuA4 histone acetyltransferase complex "GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016573///histone acetylation+++GO:0016575///histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051155///positive regulation of striated muscle cell differentiation" 56398 56398 'Chp1' mRNA 2305.74 2433.77 2375.65 49.38 51.3 53.96 67.27 64.05 67.86 51.54666667 66.39333333 3613.96 3361.81 3529.85 2371.72 3501.873333 5.06E-17 0.549340152 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030133///transport vesicle GO:0004860///protein kinase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0008017///microtubule binding+++GO:0019900///kinase binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0001578///microtubule bundle formation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0006611///protein export from nucleus+++GO:0006903///vesicle targeting+++GO:0006906///vesicle fusion+++GO:0010923///negative regulation of phosphatase activity+++GO:0015031///protein transport+++GO:0022406///membrane docking+++GO:0031122///cytoplasmic microtubule organization+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0042308///negative regulation of protein import into nucleus+++GO:0050821///protein stabilization+++GO:0051222///positive regulation of protein transport+++GO:0051259///protein complex oligomerization+++GO:0051453///regulation of intracellular pH+++GO:0060050///positive regulation of protein glycosylation+++GO:0061024///membrane organization+++GO:0061025///membrane fusion+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071073///positive regulation of phospholipid biosynthetic process+++GO:0071468///cellular response to acidic pH+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1901214///regulation of neuron death 56399 56399 'Akap8' mRNA 2411.73 2535.12 2452.03 34.1 35.42 37.05 24.85 24.63 24.76 35.52333333 24.74666667 2017.16 1946.05 1941.87 2466.293333 1968.36 1.27E-06 -0.337892968 GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0001939///female pronucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016363///nuclear matrix GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding GO:0002376///immune system process+++GO:0007076///mitotic chromosome condensation+++GO:0015031///protein transport+++GO:0016310///phosphorylation+++GO:0031065///positive regulation of histone deacetylation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0033127///regulation of histone phosphorylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0045087///innate immune response+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071380///cellular response to prostaglandin E stimulus 56401 56401 'P3h1' mRNA 464 600 555 7.95 10.12 10.08 10.53 11.6 11.59 9.383333333 11.24 707 761 754 539.6666667 740.6666667 4.21E-04 0.444924322 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane "GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006457///protein folding+++GO:0010976///positive regulation of neuron projection development+++GO:0018126///protein hydroxylation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0030199///collagen fibril organization+++GO:0030278///regulation of ossification+++GO:0030308///negative regulation of cell growth+++GO:0032963///collagen metabolic process+++GO:0050708///regulation of protein secretion+++GO:0050821///protein stabilization+++GO:0060348///bone development+++GO:1901874///negative regulation of post-translational protein modification 56403 56403 'Syncrip' mRNA 795 824 796 7.34 7.36 8.05 14.66 14.79 14.53 7.583333333 14.66 1589 1414 1468 805 1490.333333 1.82E-25 0.875757414 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0097452///GAIT complex+++GO:1990635///proximal dendrite+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0048027///mRNA 5'-UTR binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0017148///negative regulation of translation+++GO:0045727///positive regulation of translation+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0071346///cellular response to interferon-gamma+++GO:0090367///negative regulation of mRNA modification 56404 56404 'Trip4' mRNA 872.6 846.03 780.33 7.5 6.73 7 6.04 5.84 5.43 7.076666667 5.77 806.08 777.74 697.48 832.9866667 760.4333333 0.203197944 -0.142631034 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0031594///neuromuscular junction+++GO:0032991///protein-containing complex+++GO:0099053///activating signal cointegrator 1 complex GO:0002020///protease binding+++GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0016922///nuclear receptor binding+++GO:0019901///protein kinase binding+++GO:0030331///estrogen receptor binding+++GO:0035035///histone acetyltransferase binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045661///regulation of myoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0072344///rescue of stalled ribosome+++GO:1901998///toxin transport+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process" 56405 56405 'Dusp14' mRNA 1514 1648 1547 60.83 65.55 66.47 19.32 19.72 20.06 64.28333333 19.7 546 547 557 1569.666667 550 1.75E-67 -1.524643424 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 56406 56406 'Ncoa6' mRNA 562 671 545 4.45 5.06 4.51 3.66 3.52 3.69 4.673333333 3.623333333 548 515 536 592.6666667 533 0.210985877 -0.162712579 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0035097///histone methyltransferase complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035259///glucocorticoid receptor binding+++GO:0042802///identical protein binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0051427///hormone receptor binding "GO:0002793///positive regulation of peptide secretion+++GO:0006352///DNA-templated transcription, initiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0030099///myeloid cell differentiation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060716///labyrinthine layer blood vessel development+++GO:0080182///histone H3-K4 trimethylation+++GO:1900408///negative regulation of cellular response to oxidative stress+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:1903204///negative regulation of oxidative stress-induced neuron death" 56407 56407 'Trpc4ap' mRNA 2167 2182 874 37.07 36.73 15.86 17.3 17.41 20.52 29.88666667 18.41 1163 1144 1336 1741 1214.333333 0.260480726 -0.511725195 GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex "GO:0019902///phosphatase binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0048820///hair follicle maturation 56409 56409 'Nudt3' mRNA 938 898 744 24.33 22.96 20.4 23.15 20.77 22.88 22.56333333 22.26666667 1028 899 982 860 969.6666667 0.130938782 0.16410004 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0000298///endopolyphosphatase activity+++GO:0008486///diphosphoinositol-polyphosphate diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0034431///bis(5'-adenosyl)-hexaphosphatase activity+++GO:0034432///bis(5'-adenosyl)-pentaphosphatase activity+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0052840///inositol diphosphate tetrakisphosphate diphosphatase activity+++GO:0052842///inositol diphosphate pentakisphosphate diphosphatase activity GO:0071543///diphosphoinositol polyphosphate metabolic process+++GO:0071544///diphosphoinositol polyphosphate catabolic process+++GO:1901907///diadenosine pentaphosphate catabolic process+++GO:1901909///diadenosine hexaphosphate catabolic process+++GO:1901911///adenosine 5'-(hexahydrogen pentaphosphate) catabolic process 56410 56410 'Cbln3' mRNA 55.67 59.17 50.42 0.63 0.66 0.61 0.46 0.43 0.38 0.633333333 0.423333333 46.66 42.92 37.38 55.08666667 42.32 0.317330662 -0.402170713 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005515///protein binding GO:0008150///biological_process+++GO:0099558///maintenance of synapse structure 56412 56412 'Noa1' mRNA 355.17 360.23 358.81 8.39 8.36 9 9.5 9.33 8.93 8.583333333 9.253333333 462.48 438.87 421.04 358.07 440.7966667 0.035247287 0.287231823 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane GO:0000166///nucleotide binding+++GO:0005525///GTP binding GO:0006915///apoptotic process+++GO:0010941///regulation of cell death+++GO:0032543///mitochondrial translation+++GO:0043457///regulation of cellular respiration 56417 56417 'Adar' mRNA 1535 1702 1575 13.86 15.14 15.08 17.25 15.27 15.56 14.69333333 16.02666667 2193 1895 1919 1604 2002.333333 1.67E-04 0.307081122 04623///Cytosolic DNA-sensing pathway+++05162///Measles+++05164///Influenza A+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0044530///supraspliceosomal complex GO:0003677///DNA binding+++GO:0003692///left-handed Z-DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0005515///protein binding+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0001701///in utero embryonic development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002376///immune system process+++GO:0002566///somatic diversification of immune receptors via somatic mutation+++GO:0006382///adenosine to inosine editing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0009615///response to virus+++GO:0016553///base conversion or substitution editing+++GO:0030218///erythrocyte differentiation+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0035455///response to interferon-alpha+++GO:0043066///negative regulation of apoptotic process+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045070///positive regulation of viral genome replication+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060216///definitive hemopoiesis+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0098586///cellular response to virus+++GO:1900369///negative regulation of RNA interference 56418 56418 'Ykt6' mRNA 622 648 366 14.01 14.37 8.74 18.01 19.01 22.31 12.37333333 19.77666667 920 948 1103 545.3333333 990.3333333 1.53E-08 0.861088458 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite GO:0005484///SNAP receptor activity+++GO:0016740///transferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006903///vesicle targeting+++GO:0006904///vesicle docking involved in exocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion" 56419 56419 'Diaph3' mRNA 52 40 74 0.61 0.46 0.92 1.11 1.25 1.03 0.663333333 1.13 110 120 99 55.33333333 109.6666667 0.00232132 0.964680863 04810///Regulation of actin cytoskeleton GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007010///cytoskeleton organization+++GO:0016043///cellular component organization+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization 56420 56420 'Ppp4c' mRNA 1500 1645 1287 63.3 68.52 57.64 72.71 103.46 98.34 63.15333333 91.50333333 1975 2743 2585 1477.333333 2434.333333 3.61E-10 0.716499427 04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030289///protein phosphatase 4 complex GO:0004704///NF-kappaB-inducing kinase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0016311///dephosphorylation+++GO:0038061///NIK/NF-kappaB signaling 56421 56421 'Pfkp' mRNA 1654.58 1639.04 1471.16 27 26.1 25.59 32.16 29.91 29.99 26.23 30.68666667 2312.42 2073.46 2054.07 1588.26 2146.65 6.31E-09 0.423658276 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++03018///RNA degradation+++04066///HIF-1 signaling pathway+++04152///AMPK signaling pathway+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005945///6-phosphofructokinase complex+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003872///6-phosphofructokinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding+++GO:0070095///fructose-6-phosphate binding "GO:0006002///fructose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0061615///glycolytic process through fructose-6-phosphate+++GO:0061621///canonical glycolysis+++GO:1990830///cellular response to leukemia inhibitory factor" 56422 56422 'Hbs1l' mRNA 1347 1421 1321 24.56 25.4 25.65 23.54 24.46 23.59 25.20333333 23.86333333 1527 1521 1467 1363 1505 0.121823448 0.131721695 03015///mRNA surveillance pathway+++05134///Legionellosis GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0006417///regulation of translation 56424 56424 'Stub1' mRNA 4595.2 4648.61 4512.44 227.91 227.66 237.46 218.72 229.05 217.01 231.01 221.5933333 5061.44 5169.68 4856.26 4585.416667 5029.126667 0.063957961 0.121453176 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0042405///nuclear inclusion body+++GO:0101031///chaperone complex "GO:0001664///G protein-coupled receptor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0030674///protein binding, bridging+++GO:0030911///TPR domain binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0042803///protein homodimerization activity+++GO:0046332///SMAD binding+++GO:0051087///chaperone binding+++GO:0051787///misfolded protein binding+++GO:0051879///Hsp90 protein binding+++GO:0061630///ubiquitin protein ligase activity" GO:0000209///protein polyubiquitination+++GO:0002931///response to ischemia+++GO:0006281///DNA repair+++GO:0006457///protein folding+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034605///cellular response to heat+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045862///positive regulation of proteolysis+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0051604///protein maturation+++GO:0051865///protein autoubiquitination+++GO:0061684///chaperone-mediated autophagy+++GO:0070534///protein K63-linked ubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0071456///cellular response to hypoxia+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly 56426 56426 'Pdcd10' mRNA 805 778 820 23.94 22.8 25.87 32.96 31.06 30.71 24.20333333 31.57666667 1274 1172 1149 801 1198.333333 1.11E-09 0.567151091 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0090443///FAR/SIN/STRIPAK complex GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0047485///protein N-terminus binding "GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030335///positive regulation of cell migration+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0042542///response to hydrogen peroxide+++GO:0043066///negative regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0044319///wound healing, spreading of cells+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0050821///protein stabilization+++GO:0051683///establishment of Golgi localization+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0090168///Golgi reassembly+++GO:0090316///positive regulation of intracellular protein transport+++GO:1903358///regulation of Golgi organization+++GO:1903588///negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:1990830///cellular response to leukemia inhibitory factor" 56427 56427 'Tubd1' mRNA 274.99 258 222.67 6.22 5.98 6.07 6.6 5.18 6.26 6.09 6.013333333 307 229.59 274.37 251.8866667 270.32 0.673466824 0.092334909 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0007275///multicellular organism development+++GO:0030030///cell projection organization+++GO:0045880///positive regulation of smoothened signaling pathway 56428 56428 'Mtch2' mRNA 2113 2263 2153 81.85 84.65 85.8 121.72 112.29 122.59 84.1 118.8666667 3509 3219 3466 2176.333333 3398 1.46E-21 0.630269755 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005515///protein binding GO:0006089///lactate metabolic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0035701///hematopoietic stem cell migration+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045820///negative regulation of glycolytic process+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0070585///protein localization to mitochondrion+++GO:0071478///cellular response to radiation+++GO:0090152///establishment of protein localization to mitochondrial membrane involved in mitochondrial fission+++GO:0097284///hepatocyte apoptotic process+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage 56429 56429 'Dpt' mRNA 19 11 8 0.64 0.37 0.29 8.54 7.79 8.49 0.433333333 8.273333333 290 258 279 12.66666667 275.6666667 1.05E-47 4.434797187 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent GO:0007155///cell adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0030199///collagen fibril organization 56430 56430 'Clip1' mRNA 2948.07 2895.1 2909.01 28.74 27.74 29.17 23.87 22.28 21.5 28.55 22.55 2955.81 2795.13 2694.1 2917.393333 2815.013333 0.427730291 -0.064770286 04150///mTOR signaling pathway GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0035371///microtubule plus-end+++GO:0042995///cell projection+++GO:0044354///macropinosome GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051010///microtubule plus-end binding GO:0001578///microtubule bundle formation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0044861///protein transport into plasma membrane raft+++GO:1900006///positive regulation of dendrite development 56431 56431 'Dstn' mRNA 6437 6966 6596 194.01 206.87 210.9 238.8 228.52 229.95 203.9266667 232.4233333 9108 8508 8488 6666.333333 8701.333333 6.53E-11 0.371703132 GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030864///cortical actin cytoskeleton GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0000910///cytokinesis+++GO:0006928///movement of cell or subcellular component+++GO:0030042///actin filament depolymerization+++GO:0030043///actin filament fragmentation+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0048870///cell motility+++GO:0051014///actin filament severing 56433 56433 'Vps29' mRNA 1817.43 1853.5 1887.26 36.39 36.5 40.08 52.11 53.53 49.81 37.65666667 51.81666667 2993.03 3002.05 2769.71 1852.73 2921.596667 2.13E-18 0.644138185 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0030906///retromer, cargo-selective complex+++GO:0043231///intracellular membrane-bounded organelle" GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006886///intracellular protein transport+++GO:0006896///Golgi to vacuole transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi" 56434 56434 'Tspan3' mRNA 14462 14629 14235 484.54 483.13 505.96 293.08 289.12 287.69 491.21 289.9633333 10053 9679 9549 14442 9760.333333 1.24E-30 -0.577732343 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 56436 56436 'Adrm1' mRNA 1843 1909 1748 76.79 78.47 77.27 98.39 102.14 94.28 77.51 98.27 2712 2747 2514 1833.333333 2657.666667 3.52E-14 0.52497421 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008541///proteasome regulatory particle, lid subcomplex" GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0043130///ubiquitin binding+++GO:0061133///endopeptidase activator activity+++GO:0070628///proteasome binding GO:0001541///ovarian follicle development+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007286///spermatid development+++GO:0010950///positive regulation of endopeptidase activity+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0043248///proteasome assembly+++GO:0048477///oogenesis+++GO:0048538///thymus development+++GO:0060009///Sertoli cell development+++GO:0060399///positive regulation of growth hormone receptor signaling pathway+++GO:0060612///adipose tissue development+++GO:0072520///seminiferous tubule development 56437 56437 'Rrad' mRNA 37 40 40 1.42 1.51 1.62 5.03 5.19 4.78 1.516666667 5 151 152 139 39 147.3333333 5.39E-13 1.905295465 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding GO:0007165///signal transduction+++GO:0030308///negative regulation of cell growth+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1901842///negative regulation of high voltage-gated calcium channel activity 56438 56438 'Rbx1' mRNA 2903 2815 2779 102.2 97.7 103.79 103.04 114.52 108.01 101.23 108.5233333 3363 3648 3411 2832.333333 3474 6.78E-05 0.283420932 03420///Nucleotide excision repair+++04066///HIF-1 signaling pathway+++04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway+++04710///Circadian rhythm+++05131///Shigellosis+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0031467///Cul7-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0061663///NEDD8 ligase activity+++GO:0097602///cullin family protein binding GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045116///protein neddylation+++GO:0070936///protein K48-linked ubiquitination+++GO:1902499///positive regulation of protein autoubiquitination 56440 56440 'Snx1' mRNA 2936 2896 2849 80.07 77.8 82.42 75.95 80.18 72.36 80.09666667 76.16333333 3202 3300 2953 2893.666667 3151.666667 0.155211607 0.111325338 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030904///retromer complex+++GO:0030905///retromer, tubulation complex+++GO:0031901///early endosome membrane+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0098999///extrinsic component of postsynaptic endosome membrane+++GO:0099092///postsynaptic density, intracellular component" GO:0005154///epidermal growth factor receptor binding+++GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:1990459///transferrin receptor binding+++GO:1990460///leptin receptor binding "GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031175///neuron projection development+++GO:0031623///receptor internalization+++GO:0034498///early endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045732///positive regulation of protein catabolic process+++GO:0072673///lamellipodium morphogenesis" 56441 56441 'Naa80' mRNA 998.6 994.7 881.57 39.37 38.68 36.87 33.19 32.79 30.1 38.30666667 32.02666667 967.02 932.14 848.31 958.29 915.8233333 0.515693984 -0.074927524 GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:1905502///acetyl-CoA binding" GO:0006473///protein acetylation+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0017190///N-terminal peptidyl-aspartic acid acetylation+++GO:0018002///N-terminal peptidyl-glutamic acid acetylation+++GO:0030047///actin modification 56442 56442 'Serinc1' mRNA 5222 5497 5241 99.93 103.53 106.39 95.02 93.31 92.16 103.2833333 93.49666667 5713 5479 5365 5320 5519 0.579806745 0.040687787 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0019899///enzyme binding+++GO:0030674///protein binding, bridging" GO:0006629///lipid metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0044091///membrane biogenesis+++GO:1904219///positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:1904222///positive regulation of serine C-palmitoyltransferase activity 56443 56443 'Arpc1a' mRNA 3897 3965 3832 143.8 144.28 150.02 157.09 155.55 154.03 146.0333333 155.5566667 4891 4726 4640 3898 4752.333333 3.06E-06 0.273705015 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0015629///actin cytoskeleton+++GO:0035861///site of double-strand break+++GO:0036195///muscle cell projection membrane GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation 56444 56444 'Actr10' mRNA 2245.11 2187.41 2241.15 30.12 28.87 31.9 24.21 24.46 24.33 30.29666667 24.33333333 2076.64 2049.6 2021.28 2224.556667 2049.173333 0.097372937 -0.131641105 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0007018///microtubule-based movement+++GO:0098958///retrograde axonal transport of mitochondrion 56445 56445 'Dnaja2' mRNA 2785 2944 3088 52.18 54.29 61.38 56.04 55.05 53.75 55.95 54.94666667 3441 3301 3196 2939 3312.666667 0.054897796 0.157913736 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane GO:0001671///ATPase activator activity+++GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0009408///response to heat+++GO:0042026///protein refolding+++GO:0050790///regulation of catalytic activity 56447 56447 'Copz1' mRNA 4841 4894 5047 165.34 164.63 182.58 184.05 186.55 187.23 170.85 185.9433333 6185 6117 6092 4927.333333 6131.333333 2.67E-06 0.301838759 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:1901998///toxin transport" 56448 56448 'Cyp2d22' mRNA 2907 2825 2816 58.06 55.53 59.67 37.54 35.55 34.43 57.75333333 35.84 2163 2000 1920 2849.333333 2027.666667 5.80E-13 -0.503843582 00140///Steroid hormone biosynthesis+++04726///Serotonergic synapse GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006587///serotonin biosynthetic process from tryptophan+++GO:0006805///xenobiotic metabolic process+++GO:0007565///female pregnancy+++GO:0008207///C21-steroid hormone metabolic process+++GO:0010033///response to organic substance+++GO:0017144///drug metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0042416///dopamine biosynthetic process+++GO:0042417///dopamine metabolic process+++GO:0042738///exogenous drug catabolic process 56449 56449 'Ybx3' mRNA 547 456 428 17.85 14.66 14.82 12.31 10.89 12.2 15.77666667 11.8 416 360 399 477 391.6666667 0.037655522 -0.294942168 04530///Tight junction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005921///gap junction GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1905538///polysome binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0010468///regulation of gene expression+++GO:0043066///negative regulation of apoptotic process+++GO:0046622///positive regulation of organ growth+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0060546///negative regulation of necroptotic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071474///cellular hyperosmotic response+++GO:1902219///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress 56451 56451 'Suclg1' mRNA 2074 2292 2148 89.09 97.15 97.89 100.17 99.38 100.08 94.71 99.87666667 2678 2592 2588 2171.333333 2619.333333 2.94E-04 0.258560639 00020///Citrate cycle (TCA cycle)+++00640///Propanoate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0009361///succinate-CoA ligase complex (ADP-forming)+++GO:0032991///protein-containing complex+++GO:0045244///succinate-CoA ligase complex (GDP-forming) GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004775///succinate-CoA ligase (ADP-forming) activity+++GO:0004776///succinate-CoA ligase (GDP-forming) activity+++GO:0016874///ligase activity+++GO:0019003///GDP binding+++GO:0044877///protein-containing complex binding GO:0006099///tricarboxylic acid cycle+++GO:0006104///succinyl-CoA metabolic process+++GO:0006105///succinate metabolic process 56452 56452 'Orc6' mRNA 388 380 392 13.69 13.22 14.67 16.23 18.57 17.49 13.86 17.43 528 590 552 386.6666667 556.6666667 5.09E-05 0.513944892 04110///Cell cycle GO:0000808///origin recognition complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex GO:0003677///DNA binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006270///DNA replication initiation+++GO:0051782///negative regulation of cell division 56453 56453 'Mbtps1' mRNA 3316 3324 3372 42.17 41.57 45.49 36.36 37.9 38.36 43.07666667 37.54 3289 3346 3361 3337.333333 3332 0.863328977 -0.01499385 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006606///protein import into nucleus+++GO:0006629///lipid metabolic process+++GO:0007040///lysosome organization+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0060627///regulation of vesicle-mediated transport 56454 56454 'Aldh18a1' mRNA 422 408 378 6.51 6.26 6.2 6.11 5.88 6.35 6.323333333 6.113333333 451 427 454 402.6666667 444 0.371617196 0.130191329 00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004349///glutamate 5-kinase activity+++GO:0004350///glutamate-5-semialdehyde dehydrogenase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0016740///transferase activity+++GO:0042802///identical protein binding" GO:0006536///glutamate metabolic process+++GO:0006561///proline biosynthetic process+++GO:0006592///ornithine biosynthetic process+++GO:0008152///metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009266///response to temperature stimulus+++GO:0016310///phosphorylation+++GO:0019240///citrulline biosynthetic process+++GO:0055129///L-proline biosynthetic process 56455 56455 'Dynll1' mRNA 4165.27 4255.73 3983.36 117.21 117.97 118.91 175.25 191.88 175.35 118.03 180.8266667 7160.38 7653.48 6934.13 4134.786667 7249.33 3.96E-39 0.799565392 04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005929///cilium+++GO:0008180///COP9 signalosome+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0030286///dynein complex+++GO:0072686///mitotic spindle+++GO:1904115///axon cytoplasm GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding+++GO:0097110///scaffold protein binding "GO:0006915///apoptotic process+++GO:0007017///microtubule-based process+++GO:0007286///spermatid development+++GO:0035721///intraciliary retrograde transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042326///negative regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0044458///motile cilium assembly+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0060271///cilium assembly+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed" 56456 56456 'Actl6a' mRNA 722 761 709 20.59 21.35 21.4 31.08 31.92 27.53 21.11333333 30.17666667 1245 1253 1067 730.6666667 1188.333333 1.14E-12 0.690230824 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016514///SWI/SNF complex+++GO:0031011///Ino80 complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0001825///blastocyst formation+++GO:0003407///neural retina development+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007399///nervous system development+++GO:0021510///spinal cord development+++GO:0040008///regulation of growth+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation 56457 56457 'Clptm1' mRNA 4832 5211 2864 97.6 103.89 61.66 58.19 87.01 77.1 87.71666667 74.1 3319 4826 4229 4302.333333 4124.666667 0.88450994 -0.055674809 GO:0009897///external side of plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0033081///regulation of T cell differentiation in thymus 56458 56458 'Foxo1' mRNA 920 905 671 8.82 8.53 6.82 4.91 4.83 4.91 8.056666667 4.883333333 590 567 571 832 576 3.84E-06 -0.536559124 04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04933///AGE-RAGE signaling pathway in diabetic complications+++04936///Alcoholic liver disease+++05131///Shigellosis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05215///Prostate cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008134///transcription factor binding+++GO:0031490///chromatin DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043565///sequence-specific DNA binding+++GO:0051721///protein phosphatase 2A binding+++GO:1990841///promoter-specific chromatin binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001568///blood vessel development+++GO:0006111///regulation of gluconeogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008286///insulin receptor signaling pathway+++GO:0009267///cellular response to starvation+++GO:0010508///positive regulation of autophagy+++GO:0030154///cell differentiation+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0034599///cellular response to oxidative stress+++GO:0042127///regulation of cell proliferation+++GO:0042593///glucose homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045732///positive regulation of protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070166///enamel mineralization+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070542///response to fatty acid+++GO:0071455///cellular response to hyperoxia+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071732///cellular response to nitric oxide+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097150///neuronal stem cell population maintenance+++GO:1902617///response to fluoride+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000377///regulation of reactive oxygen species metabolic process" 56459 56459 'Sae1' mRNA 2088 2128 2088 60.01 60.28 63.72 69.7 74.6 72.86 61.33666667 72.38666667 2788 2914 2822 2101.333333 2841.333333 1.27E-09 0.423524366 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031510///SUMO activating enzyme complex GO:0008022///protein C-terminus binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity+++GO:0019948///SUMO activating enzyme activity+++GO:0043008///ATP-dependent protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006464///cellular protein modification process+++GO:0016925///protein sumoylation+++GO:0032446///protein modification by small protein conjugation+++GO:0033235///positive regulation of protein sumoylation 56460 56460 'Pkp3' mRNA 702 686 628 13.7 13.14 13 12.65 11.22 13.45 13.28 12.44 747 646 765 672 719.3333333 0.506335723 0.086999093 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005914///spot adherens junction+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:1990124///messenger ribonucleoprotein complex GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0050839///cell adhesion molecule binding GO:0002159///desmosome assembly+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0072659///protein localization to plasma membrane+++GO:0098609///cell-cell adhesion+++GO:1902373///negative regulation of mRNA catabolic process 56461 56461 'Kcnip3' mRNA 430 450 452 8.53 8.77 9.48 4.41 4.02 4.21 8.926666667 4.213333333 255 226 237 444 239.3333333 6.80E-11 -0.905281682 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032993///protein-DNA complex+++GO:0043679///axon terminus "GO:0000287///magnesium ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005509///calcium ion binding+++GO:0008022///protein C-terminus binding+++GO:0015459///potassium channel regulator activity+++GO:0043565///sequence-specific DNA binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006886///intracellular protein transport+++GO:0006915///apoptotic process+++GO:0019233///sensory perception of pain+++GO:0032026///response to magnesium ion+++GO:0034765///regulation of ion transmembrane transport+++GO:0043523///regulation of neuron apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0071805///potassium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport" 56462 56462 'Mtch1' mRNA 1547 1509 1451 53.2 51.43 53.27 61.94 54.59 62.4 52.63333333 59.64333333 2066 1759 1996 1502.333333 1940.333333 7.39E-06 0.356509018 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process 56463 56463 'Snd1' mRNA 2132 2245 2264 34.82 35.87 38.83 38.23 37.94 34.4 36.50666667 36.85666667 2610 2495 2307 2213.666667 2470.666667 0.086728734 0.144680425 05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016442///RISC complex+++GO:0042470///melanosome+++GO:0097433///dense body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:1905172///RISC complex binding "GO:0006401///RNA catabolic process+++GO:0006402///mRNA catabolic process+++GO:0010564///regulation of cell cycle process+++GO:0010587///miRNA catabolic process+++GO:0031047///gene silencing by RNA+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 56464 56464 'Ctsf' mRNA 3050 3116 3059 89.41 89.9 95.15 46.61 51.1 46.13 91.48666667 47.94666667 1827 1955 1750 3075 1844 1.24E-24 -0.749580518 04142///Lysosome+++04210///Apoptosis GO:0005615///extracellular space+++GO:0005764///lysosome GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0051603///proteolysis involved in cellular protein catabolic process 56468 56468 'Socs5' mRNA 676 672 452 7.78 7.4 5.53 8.19 10.12 9.16 6.903333333 9.156666667 826 965 894 600 895 1.56E-05 0.574605051 04630///JAK-STAT signaling pathway+++04917///Prolactin signaling pathway GO:0005737///cytoplasm+++GO:0005942///phosphatidylinositol 3-kinase complex GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0019210///kinase inhibitor activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0007259///JAK-STAT cascade+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032715///negative regulation of interleukin-6 production+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045627///positive regulation of T-helper 1 cell differentiation+++GO:0045629///negative regulation of T-helper 2 cell differentiation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0050728///negative regulation of inflammatory response+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0097699///vascular endothelial cell response to fluid shear stress+++GO:1904988///negative regulation of endothelial cell activation 56469 56469 'Pias1' mRNA 2321 2483 2343 29.58 30.74 31.61 21.68 19.95 22.6 30.64333333 21.41 2009 1767 1997 2382.333333 1924.333333 2.10E-05 -0.32066594 04120///Ubiquitin mediated proteolysis+++04630///JAK-STAT signaling pathway+++05160///Hepatitis C GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0016607///nuclear speck GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061665///SUMO ligase activity "GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007259///JAK-STAT cascade+++GO:0007283///spermatogenesis+++GO:0008542///visual learning+++GO:0016925///protein sumoylation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033235///positive regulation of protein sumoylation+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0065004///protein-DNA complex assembly" 56470 56470 'Rgs19' mRNA 157 128 165 6.16 5.37 6.94 29.99 28.64 25.51 6.156666667 28.04666667 862 816 714 150 797.3333333 6.90E-63 2.394604448 GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0045121///membrane raft GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding GO:0009968///negative regulation of signal transduction+++GO:0045471///response to ethanol 56471 56471 'Stmn4' mRNA 0 0 1 0 0 0.05 0.04 0.16 0.04 0.016666667 0.08 1 4 1 0.333333333 2 0.38403524 2.480497221 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0015631///tubulin binding GO:0007019///microtubule depolymerization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031175///neuron projection development 56473 56473 'Fads2' mRNA 7226 7644 6804 136.85 142.47 136.69 127.01 118.64 125.56 138.67 123.7366667 7716 7039 7386 7224.666667 7380.333333 0.789247049 0.019742562 00592///alpha-Linolenic acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0016213///linoleoyl-CoA desaturase activity+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process 56480 56480 'Tbk1' mRNA 758 769 806 13.73 13.7 15.48 16.79 16.37 16.95 14.30333333 16.70333333 1067 1016 1043 777.6666667 1042 2.63E-05 0.408297035 04014///Ras signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04657///IL-17 signaling pathway+++04936///Alcoholic liver disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05135///Yersinia infection+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016239///positive regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031323///regulation of cellular metabolic process+++GO:0032479///regulation of type I interferon production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044565///dendritic cell proliferation+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:1904417///positive regulation of xenophagy 56484 56484 'Foxo3' mRNA 773 733 847 6.02 5.61 7 5.71 4.77 5.38 6.21 5.286666667 845 689 770 784.3333333 768 0.765168305 -0.047494973 01521///EGFR tyrosine kinase inhibitor resistance+++04062///Chemokine signaling pathway+++04068///FoxO signaling pathway+++04137///Mitophagy - animal+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04361///Axon regeneration+++04722///Neurotrophin signaling pathway+++04917///Prolactin signaling pathway+++04936///Alcoholic liver disease+++05131///Shigellosis+++05208///Chemical carcinogenesis - reactive oxygen species+++05213///Endometrial cancer+++05223///Non-small cell lung cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001221///transcription cofactor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0019901///protein kinase binding+++GO:0031490///chromatin DNA binding+++GO:0034246///mitochondrial sequence-specific DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001542///ovulation from ovarian follicle+++GO:0001544///initiation of primordial ovarian follicle growth+++GO:0001547///antral ovarian follicle growth+++GO:0001556///oocyte maturation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006390///mitochondrial transcription+++GO:0006417///regulation of translation+++GO:0006915///apoptotic process+++GO:0007568///aging+++GO:0010508///positive regulation of autophagy+++GO:0014737///positive regulation of muscle atrophy+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0030336///negative regulation of cell migration+++GO:0031667///response to nutrient levels+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0034599///cellular response to oxidative stress+++GO:0042149///cellular response to glucose starvation+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0042594///response to starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048854///brain morphogenesis+++GO:0070542///response to fatty acid+++GO:0071333///cellular response to glucose stimulus+++GO:0071386///cellular response to corticosterone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071548///response to dexamethasone+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097150///neuronal stem cell population maintenance+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904646///cellular response to amyloid-beta+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1990785///response to water-immersion restraint stress+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process" 56485 56485 'Slc2a5' mRNA 5 7 7 0.13 0.18 0.19 0.23 0.09 0.02 0.166666667 0.113333333 10 4 1 6.333333333 5 0.808285489 -0.367172853 04973///Carbohydrate digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0042383///sarcolemma GO:0005353///fructose transmembrane transporter activity+++GO:0005355///glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0070061///fructose binding GO:0003044///regulation of systemic arterial blood pressure mediated by a chemical signal+++GO:0008643///carbohydrate transport+++GO:0009750///response to fructose+++GO:0015755///fructose transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071332///cellular response to fructose stimulus+++GO:1904659///glucose transmembrane transport+++GO:1990539///fructose import across plasma membrane 56486 56486 'Gabarap' mRNA 6892 6866 6474 382.5 376.5 381.22 524.1 526.6 523.92 380.0733333 524.8733333 10834 10614 10470 6744 10639.33333 2.99E-40 0.646451219 04068///FoxO signaling pathway+++04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04212///Longevity regulating pathway - worm+++04621///NOD-like receptor signaling pathway+++04727///GABAergic synapse GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005776///autophagosome+++GO:0005790///smooth endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005886///plasma membrane+++GO:0005930///axoneme+++GO:0012505///endomembrane system+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0097225///sperm midpiece GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048487///beta-tubulin binding+++GO:0050811///GABA receptor binding GO:0000045///autophagosome assembly+++GO:0000226///microtubule cytoskeleton organization+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006995///cellular response to nitrogen starvation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035020///regulation of Rac protein signal transduction+++GO:1902524///positive regulation of protein K48-linked ubiquitination 56488 56488 'Nxt1' mRNA 311 371 325 20.67 24.28 22.78 29 34.31 33.6 22.57666667 32.30333333 500 579 561 335.6666667 546.6666667 2.22E-07 0.694236021 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0044613///nuclear pore central transport channel GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006405///RNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051028///mRNA transport 56489 56489 'Ikbke' mRNA 51 53 56 0.9 0.91 1.01 9.51 9.67 8.86 0.94 9.346666667 634 627 570 53.33333333 610.3333333 1.31E-92 3.504230521 04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++04657///IL-17 signaling pathway+++04936///Alcoholic liver disease+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05171///Coronavirus disease - COVID-19+++05207///Chemical carcinogenesis - receptor activation+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004704///NF-kappaB-inducing kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008384///IkappaB kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0006955///immune response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007252///I-kappaB phosphorylation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010467///gene expression+++GO:0010884///positive regulation of lipid storage+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0034340///response to type I interferon+++GO:0035456///response to interferon-beta+++GO:0038061///NIK/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0048255///mRNA stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0098586///cellular response to virus 56490 56490 'Zbtb20' mRNA 44528 45237 42861 247.63 247.16 259.89 105.04 97.68 96.73 251.56 99.81666667 25290 21725 23559 44208.66667 23524.66667 2.19E-69 -0.923045128 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0045821///positive regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0055088///lipid homeostasis+++GO:0071333///cellular response to glucose stimulus" 56491 56491 'Vapb' mRNA 314 302 180 2.38 2.25 1.45 1.61 1.79 1.74 2.026666667 1.713333333 245 266 256 265.3333333 255.6666667 0.84906881 -0.054256127 04979///Cholesterol metabolism+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019899///enzyme binding+++GO:0033149///FFAT motif binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0048487///beta-tubulin binding GO:0006874///cellular calcium ion homeostasis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006986///response to unfolded protein+++GO:0007029///endoplasmic reticulum organization+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0044828///negative regulation by host of viral genome replication+++GO:0044829///positive regulation by host of viral genome replication+++GO:0044830///modulation by host of viral RNA genome replication+++GO:0045070///positive regulation of viral genome replication+++GO:0046725///negative regulation by virus of viral protein levels in host cell+++GO:0061817///endoplasmic reticulum-plasma membrane tethering+++GO:0090114///COPII-coated vesicle budding+++GO:0090158///endoplasmic reticulum membrane organization 56494 56494 'Gosr2' mRNA 2434.51 2496.32 2633.76 40.9 41.56 47.6 45.07 47.5 47.12 43.35333333 46.56333333 3044.33 3138.01 3087.54 2521.53 3089.96 3.51E-04 0.279694764 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0031902///late endosome membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity "GO:0006623///protein targeting to vacuole+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006896///Golgi to vacuole transport+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0061025///membrane fusion" 56495 56495 'Get3' mRNA 1469 1450 784 70.45 68.58 39.95 53.33 50.93 47.66 59.66 50.64 1274 1187 1101 1234.333333 1187.333333 0.872999475 -0.054947395 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0043529///GET complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0045048///protein insertion into ER membrane+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 56496 56496 'Tspan6' mRNA 1006 1164 990 32.8 37.41 34.26 32.74 34.6 36.23 34.82333333 34.52333333 1151 1191 1232 1053.333333 1191.333333 0.089904408 0.168144579 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0039532///negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 56501 56501 'Elf4' mRNA 29 22 28 0.26 0.19 0.27 1.97 1.56 1.71 0.24 1.746666667 253 195 210 26.33333333 219.3333333 1.43E-30 3.042818306 04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016605///PML body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001787///natural killer cell proliferation+++GO:0001866///NK T cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 56503 56503 'Ankrd49' mRNA 254 277 273 5.79 6.32 6.69 6.66 6.61 7.13 6.266666667 6.8 333 323 346 268 334 0.05300255 0.304966055 GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function "GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated" 56504 56504 'Srpk3' mRNA 93 85 87 2.68 2.36 2.62 0.98 1.28 0.9 2.553333333 1.053333333 39 51 35 88.33333333 41.66666667 6.34E-04 -1.094667139 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000245///spliceosomal complex assembly+++GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0050684///regulation of mRNA processing+++GO:0060537///muscle tissue development 56505 56505 'Ruvbl1' mRNA 1354 1466 1284 47.21 50.4 47.5 36.38 34.7 38.32 48.37 36.46666667 1199 1116 1222 1368 1179 0.008526075 -0.225019099 04310///Wnt signaling pathway GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0031011///Ino80 complex+++GO:0032991///protein-containing complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0071339///MLL1 complex+++GO:0097255///R2TP complex+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0003678///DNA helicase activity+++GO:0003713///transcription coactivator activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0043138///3'-5' DNA helicase activity+++GO:0043139///5'-3' DNA helicase activity+++GO:0043531///ADP binding+++GO:0051117///ATPase binding "GO:0000492///box C/D snoRNP assembly+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010756///positive regulation of plasminogen activation+++GO:0016573///histone acetylation+++GO:0032508///DNA duplex unwinding+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000269///regulation of fibroblast apoptotic process" 56506 56506 'Cib2' mRNA 1605 1668.99 1594 68.09 69.87 71.74 20.3 23.57 27.02 69.9 23.63 551 623 707 1622.663333 627 1.61E-42 -1.382009271 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005927///muscle tendon junction+++GO:0016020///membrane+++GO:0031594///neuromuscular junction+++GO:0032420///stereocilium+++GO:0032437///cuticular plate+++GO:0042383///sarcolemma+++GO:0042995///cell projection GO:0000287///magnesium ion binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0045494///photoreceptor cell maintenance+++GO:0055074///calcium ion homeostasis+++GO:0071318///cellular response to ATP 56508 56508 'Rapgef4' mRNA 1118.38 1250.24 1119.01 14.72 16.26 15.46 4.58 5.16 4.64 15.48 4.793333333 402.99 445 396.01 1162.543333 414.6666667 1.06E-48 -1.498365675 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04670///Leukocyte transendothelial migration+++04911///Insulin secretion GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005929///cilium+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044316///cone cell pedicle+++GO:0060076///excitatory synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding GO:0006887///exocytosis+++GO:0007165///signal transduction+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0017156///calcium ion regulated exocytosis+++GO:0017157///regulation of exocytosis+++GO:0019933///cAMP-mediated signaling+++GO:0030073///insulin secretion+++GO:0035556///intracellular signal transduction+++GO:0050714///positive regulation of protein secretion+++GO:0050773///regulation of dendrite development+++GO:0050790///regulation of catalytic activity+++GO:0050805///negative regulation of synaptic transmission+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0099175///regulation of postsynapse organization+++GO:1904457///positive regulation of neuronal action potential 56513 56513 'Pard6a' mRNA 303 318 277 14.62 15.19 14.17 9.87 10.11 11.5 14.66 10.49333333 235 235 265 299.3333333 245 0.071574441 -0.298510549 04015///Rap1 signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0045177///apical part of cell GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding GO:0001933///negative regulation of protein phosphorylation+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030010///establishment of cell polarity+++GO:0045217///cell-cell junction maintenance+++GO:0050714///positive regulation of protein secretion+++GO:0051301///cell division+++GO:0060341///regulation of cellular localization+++GO:1904781///positive regulation of protein localization to centrosome 56515 56515 'Rnf138' mRNA 615 617 573 11.44 11.34 11.32 11.8 11.92 11.79 11.36666667 11.83666667 728 717 703 601.6666667 716 0.025246101 0.240086647 GO:0005694///chromosome+++GO:0035861///site of double-strand break GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010792///DNA double-strand break processing involved in repair via single-strand annealing+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:1990830///cellular response to leukemia inhibitory factor 56516 56516 'Rbms2' mRNA 1873 1828.01 1776 19 18.26 19.14 19.08 16.18 17.93 18.8 17.73 2173 1797 1982 1825.67 1984 0.235479453 0.106743014 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding 56517 56517 'Slc22a21' mRNA 127.56 120.2 109.92 2.22 2.15 2.29 2.16 1.83 1.85 2.22 1.946666667 121.76 106.75 113.76 119.2266667 114.09 0.807712871 -0.077237457 05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031231///intrinsic component of peroxisomal membrane+++GO:0031526///brush border membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015226///carnitine transmembrane transporter activity+++GO:0015651///quaternary ammonium group transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0030165///PDZ domain binding+++GO:1901235///(R)-carnitine transmembrane transporter activity GO:0006811///ion transport+++GO:0009609///response to symbiotic bacterium+++GO:0015697///quaternary ammonium group transport+++GO:0015879///carnitine transport+++GO:0055085///transmembrane transport+++GO:0060731///positive regulation of intestinal epithelial structure maintenance+++GO:0070715///sodium-dependent organic cation transport+++GO:1902270///(R)-carnitine transmembrane transport 56520 56520 'Nme4' mRNA 172 170 161 12.54 12.53 12.49 27.36 25.23 23.47 12.52 25.35333333 422 383 350 167.6666667 385 1.20E-14 1.187196574 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding+++GO:1901612///cardiolipin binding GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0006869///lipid transport+++GO:0009117///nucleotide metabolic process+++GO:0016310///phosphorylation 56522 56522 'Papolb' mRNA 4 3 1 0.1 0.07 0.03 0.04 0.09 0.02 0.066666667 0.05 2 4 1 2.666666667 2.333333333 0.929085204 -0.18214046 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0043631///RNA polyadenylation 56523 56523 'Pmfbp1' mRNA 2 2 0 0.03 0.03 0 0.02 0.01 0.01 0.02 0.013333333 2 1 1 1.333333333 1.333333333 0.998591786 0.01143668 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097224///sperm connecting piece GO:0003674///molecular_function GO:0007283///spermatogenesis 56524 56524 'Mpp6' mRNA 251 285 245 5.97 6.85 6.19 9.29 8.66 8.27 6.336666667 8.74 440 406 384 260.3333333 410 5.20E-06 0.644343282 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004385///guanylate kinase activity+++GO:0005515///protein binding GO:0046037///GMP metabolic process+++GO:0046710///GDP metabolic process 56525 56525 'Zfp235' mRNA 366.49 396.32 360 4.31 4.96 4.75 3.07 3.13 2.72 4.673333333 2.973333333 276 291 237 374.27 268 0.001140793 -0.491584222 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 56526 56526 'Septin6' mRNA 888 811 885 11.44 10.33 12.1 8.73 8.47 8.28 11.29 8.493333333 797 739 730 861.3333333 755.3333333 0.067065237 -0.20377843 05100///Bacterial invasion of epithelial cells+++05131///Shigellosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005940///septin ring+++GO:0008021///synaptic vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0031105///septin complex+++GO:0031514///motile cilium+++GO:0032153///cell division site+++GO:0032154///cleavage furrow+++GO:0032173///septin collar+++GO:0042995///cell projection+++GO:0043679///axon terminus+++GO:0097227///sperm annulus+++GO:0098793///presynapse" GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0060090///molecular adaptor activity GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0034613///cellular protein localization+++GO:0051301///cell division+++GO:0060271///cilium assembly+++GO:0061640///cytoskeleton-dependent cytokinesis 56527 56527 'Mast1' mRNA 228 190 204 3.15 2.57 3.05 1.32 0.88 1.02 2.923333333 1.073333333 109 68 79 207.3333333 85.33333333 1.06E-08 -1.296821965 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0007420///brain development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 56529 56529 'Sec11a' mRNA 1686 1597 1662 92.56 87.11 97.2 118.48 119.92 119.81 92.29 119.4033333 2476 2446 2410 1648.333333 2444 3.70E-14 0.555270997 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis 56530 56530 'Cnpy2' mRNA 2690 2565 2517 168.13 158.51 167.1 156.02 165.43 154.4 164.58 158.6166667 2855 2954 2731 2590.666667 2846.666667 0.100585387 0.12454697 GO:0005783///endoplasmic reticulum GO:0005515///protein binding GO:0010629///negative regulation of gene expression+++GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:1905599///positive regulation of low-density lipoprotein receptor activity 56531 56531 'Ylpm1' mRNA 1574 1512 1187 7.68 7.31 6.04 5.65 4.87 4.98 7.01 5.166666667 1318 1113 1131 1424.333333 1187.333333 0.008302443 -0.2708088 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck "GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032204///regulation of telomere maintenance 56532 56532 'Ripk3' mRNA 32 36 38 0.97 1.07 1.21 12.37 12.98 11.56 1.083333333 12.30333333 468 479 423 35.33333333 456.6666667 1.08E-72 3.679945703 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04668///TNF signaling pathway+++05132///Salmonella infection GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004704///NF-kappaB-inducing kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding "GO:0001914///regulation of T cell mediated cytotoxicity+++GO:0002819///regulation of adaptive immune response+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010922///positive regulation of phosphatase activity+++GO:0010940///positive regulation of necrotic cell death+++GO:0012501///programmed cell death+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0032649///regulation of interferon-gamma production+++GO:0033077///T cell differentiation in thymus+++GO:0038061///NIK/NF-kappaB signaling+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0046006///regulation of activated T cell proliferation+++GO:0046777///protein autophosphorylation+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051347///positive regulation of transferase activity+++GO:0051351///positive regulation of ligase activity+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0051607///defense response to virus+++GO:0060545///positive regulation of necroptotic process+++GO:0070235///regulation of activation-induced cell death of T cells+++GO:0070266///necroptotic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0090312///positive regulation of protein deacetylation+++GO:0097300///programmed necrotic cell death+++GO:0097527///necroptotic signaling pathway+++GO:0097528///execution phase of necroptosis+++GO:1990000///amyloid fibril formation+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2000452///regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 56533 56533 'Rgs17' mRNA 15 10 9 0.1 0.06 0.06 0.07 0.08 0.08 0.073333333 0.076666667 13 14 13 11.33333333 13.33333333 0.81278904 0.227684486 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0001975///response to amphetamine+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0050790///regulation of catalytic activity 56534 56534 'Hspb3' mRNA 0 0 1 0 0 0.09 0.08 0 0 0.03 0.026666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck 56535 56535 'Pex3' mRNA 712.44 745.78 685.09 19.19 19.1 18.93 12.78 14.21 14.39 19.07333333 13.79333333 574.78 648.14 617.46 714.4366667 613.46 0.046526137 -0.229899131 04146///Peroxisome GO:0005654///nucleoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0032994///protein-lipid complex "GO:0008289///lipid binding+++GO:0030674///protein binding, bridging" GO:0007031///peroxisome organization+++GO:0016557///peroxisome membrane biogenesis+++GO:0045046///protein import into peroxisome membrane 56538 56538 'Klk11' mRNA 1 3 5 0.07 0.21 0.38 0.13 0.13 0.06 0.22 0.106666667 2 2 1 3 1.666666667 0.669541333 -0.880376129 GO:0005576///extracellular region+++GO:0030141///secretory granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 56541 56541 'Habp4' mRNA 642 648 192 13.9 13.81 4.41 2.92 3.76 4.71 10.70666667 3.796666667 155 195 242 494 197.3333333 0.024963384 -1.308627065 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0015030///Cajal body+++GO:0016528///sarcoplasm+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0030017///sarcomere+++GO:0097504///Gemini of coiled bodies GO:0003723///RNA binding+++GO:0005540///hyaluronic acid binding+++GO:0032183///SUMO binding GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0008380///RNA splicing+++GO:0030212///hyaluronan metabolic process+++GO:0030578///PML body organization+++GO:0033120///positive regulation of RNA splicing+++GO:0043392///negative regulation of DNA binding+++GO:0045948///positive regulation of translational initiation+++GO:0071260///cellular response to mechanical stimulus 56542 56542 'Cilk1' mRNA 390 425 398 3.1 3.32 3.35 3.23 3.01 3.19 3.256666667 3.143333333 469 427 449 404.3333333 448.3333333 0.349105593 0.13678819 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097542///ciliary tip+++GO:0097546///ciliary base GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0016310///phosphorylation+++GO:0030030///cell projection organization+++GO:0035556///intracellular signal transduction+++GO:0035720///intraciliary anterograde transport+++GO:0035721///intraciliary retrograde transport+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly 56543 56543 'Kcnd3' mRNA 72 61 77 0.43 0.48 0.59 0.44 0.29 0.2 0.5 0.31 80 46 38 70 54.66666667 0.358909554 -0.37871631 05017///Spinocerebellar ataxia GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0008076///voltage-gated potassium channel complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0034705///potassium channel complex+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005250///A-type (transient outward) potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071773///cellular response to BMP stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086009///membrane repolarization+++GO:0086065///cell communication involved in cardiac conduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0099625///ventricular cardiac muscle cell membrane repolarization+++GO:1990573///potassium ion import across plasma membrane 56544 56544 'Vmn2r1' mRNA 8.91 14.9 19.09 0.09 0.15 0.2 0.16 0.13 0.09 0.146666667 0.126666667 18.63 14.86 10.1 14.3 14.53 0.998591786 0.008725696 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0038022///G protein-coupled olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone+++GO:0030182///neuron differentiation+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 56546 56546 'Sec1' mRNA 10.02 6.93 11.21 0.26 0.15 0.31 0.66 0.57 0.4 0.24 0.543333333 27.35 24.46 16 9.386666667 22.60333333 0.060327641 1.290590408 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008107///galactoside 2-alpha-L-fucosyltransferase activity+++GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" GO:0001954///positive regulation of cell-matrix adhesion+++GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0021772///olfactory bulb development+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0036065///fucosylation+++GO:0097150///neuronal stem cell population maintenance+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin 56550 56550 'Ube2d2a' mRNA 2991 2902 1971 67.13 64.14 46.94 54.48 56.34 57.46 59.40333333 56.09333333 2791 2819 2850 2621.333333 2820 0.40730399 0.102473303 04013///MAPK signaling pathway - fly+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination 56551 56551 'Txn2' mRNA 3442 3536 3190 162.85 165.15 160.13 170 167.83 160.24 162.71 166.0233333 4125 3972 3760 3389.333333 3952.333333 6.58E-04 0.210937813 04621///NOD-like receptor signaling pathway+++05012///Parkinson disease+++05132///Salmonella infection+++05418///Fluid shear stress and atherosclerosis GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0008113///peptide-methionine (S)-S-oxide reductase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0033743///peptide-methionine (R)-S-oxide reductase activity+++GO:0044877///protein-containing complex binding GO:0001666///response to hypoxia+++GO:0006662///glycerol ether metabolic process+++GO:0006979///response to oxidative stress+++GO:0009725///response to hormone+++GO:0009749///response to glucose+++GO:0014070///response to organic cyclic compound+++GO:0031669///cellular response to nutrient levels+++GO:0042493///response to drug+++GO:0045454///cell redox homeostasis+++GO:0048678///response to axon injury 56554 56554 'Raet1d' mRNA 0 0 3 0 0 0.15 2.83 4.27 3.97 0.05 3.69 70.31 104.49 95.01 1 89.93666667 3.14E-12 6.473457633 04650///Natural killer cell mediated cytotoxicity GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0044214///spanning component of plasma membrane+++GO:0046658///anchored component of plasma membrane GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding GO:0006955///immune response+++GO:0042267///natural killer cell mediated cytotoxicity 56612 56612 'Pfdn5' mRNA 2950 2837 2781 314.29 300.29 314.46 224.89 225.9 233.25 309.68 228.0133333 2412 2357 2413 2856 2394 5.87E-05 -0.266391287 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016272///prefoldin complex+++GO:0045111///intermediate filament cytoskeleton GO:0001540///amyloid-beta binding+++GO:0051082///unfolded protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006457///protein folding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060041///retina development in camera-type eye+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1905907///negative regulation of amyloid fibril formation" 56613 56613 'Rps6ka4' mRNA 804 820 763 13.9 13.93 13.98 21.09 19.18 18.78 13.93666667 19.68333333 1398 1243 1206 795.6666667 1282.333333 2.14E-14 0.676425471 04010///MAPK signaling pathway+++04668///TNF signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0033129///positive regulation of histone phosphorylation+++GO:0035066///positive regulation of histone acetylation+++GO:0035556///intracellular signal transduction+++GO:0043987///histone H3-S10 phosphorylation+++GO:0043988///histone H3-S28 phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070498///interleukin-1-mediated signaling pathway" 56615 56615 'Mgst1' mRNA 2934 2911 2868 198.41 194.67 205.78 264.29 279.05 267.37 199.62 270.2366667 4481 4611 4381 2904.333333 4491 4.80E-23 0.617006986 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0043295///glutathione binding GO:0006749///glutathione metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0010243///response to organonitrogen compound+++GO:0032496///response to lipopolysaccharide+++GO:0034635///glutathione transport+++GO:0042493///response to drug+++GO:0071449///cellular response to lipid hydroperoxide+++GO:0098869///cellular oxidant detoxification 56619 56619 'Clec4e' mRNA 54 59 65 1.35 1.36 1.69 25.42 24 26.73 1.466666667 25.38333333 1231 1140 1235 59.33333333 1202 2.27E-191 4.327820082 04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis GO:0001891///phagocytic cup+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0038187///pattern recognition receptor activity+++GO:0046872///metal ion binding+++GO:0051861///glycolipid binding GO:0001819///positive regulation of cytokine production+++GO:0002221///pattern recognition receptor signaling pathway+++GO:0002292///T cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0042742///defense response to bacterium+++GO:0044419///interspecies interaction between organisms+++GO:0045087///innate immune response+++GO:0061760///antifungal innate immune response 56620 56620 'Clec4n' mRNA 70 88 70 3.47 4.33 3.66 87.65 84.41 84.75 3.82 85.60333333 2004 1881 1875 76 1920 1.01E-296 4.648343619 04625///C-type lectin receptor signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0038187///pattern recognition receptor activity+++GO:0046872///metal ion binding GO:0001819///positive regulation of cytokine production+++GO:0001878///response to yeast+++GO:0001879///detection of yeast+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044419///interspecies interaction between organisms+++GO:0045087///innate immune response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050832///defense response to fungus+++GO:0061760///antifungal innate immune response+++GO:1902533///positive regulation of intracellular signal transduction+++GO:2000318///positive regulation of T-helper 17 type immune response 56622 56622 'Adam21' mRNA 11 9 6 0.21 0.17 0.12 0.2 0.13 0.19 0.166666667 0.173333333 12 8 11 8.666666667 10.33333333 0.823550341 0.247200535 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:1990913///sperm head plasma membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0008584///male gonad development 56626 56626 'Poll' mRNA 490 537 588 11.55 12.41 14.61 9.74 10.16 10.01 12.85666667 9.97 478 489 473 538.3333333 480 0.217886658 -0.180554203 03410///Base excision repair+++03450///Non-homologous end-joining GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016829///lyase activity+++GO:0034061///DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity "GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006287///base-excision repair, gap-filling+++GO:0006289///nucleotide-excision repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0071897///DNA biosynthetic process" 56631 56631 'Trim17' mRNA 941.45 912.99 805.25 22.97 21.84 20.76 16.6 16.47 17.9 21.85666667 16.99 784.74 756.21 818.32 886.5633333 786.4233333 0.07797041 -0.182348181 GO:0005737///cytoplasm "GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0045087///innate immune response+++GO:0051865///protein autoubiquitination 56632 56632 'Sphk2' mRNA 1642.4 1607.01 1429.87 29.6 29.32 27.64 28.88 28.63 25.2 28.85333333 27.57 1742.41 1655.2 1486.7 1559.76 1628.103333 0.627133626 0.051568001 00600///Sphingolipid metabolism+++04020///Calcium signaling pathway+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04370///VEGF signaling pathway+++04371///Apelin signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05152///Tuberculosis GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0001727///lipid kinase activity+++GO:0003951///NAD+ kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008481///sphinganine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017050///D-erythro-sphingosine kinase activity+++GO:0031493///nucleosomal histone binding+++GO:0038036///sphingosine-1-phosphate receptor activity "GO:0001568///blood vessel development+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006665///sphingolipid metabolic process+++GO:0006669///sphinganine-1-phosphate biosynthetic process+++GO:0006670///sphingosine metabolic process+++GO:0007420///brain development+++GO:0007565///female pregnancy+++GO:0008284///positive regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0031064///negative regulation of histone deacetylation+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033008///positive regulation of mast cell activation involved in immune response+++GO:0043065///positive regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043306///positive regulation of mast cell degranulation+++GO:0043977///histone H2A-K5 acetylation+++GO:0043980///histone H2B-K12 acetylation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0046512///sphingosine biosynthetic process+++GO:0046834///lipid phosphorylation+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090280///positive regulation of calcium ion import+++GO:1901726///negative regulation of histone deacetylase activity+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:1904959///regulation of cytochrome-c oxidase activity+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:2001169///regulation of ATP biosynthetic process" 56636 56636 'Fgf21' mRNA 31 44 30 2.12 2.98 2.18 1.25 0.98 1.55 2.426666667 1.26 21 16 25 35 20.66666667 0.138270274 -0.767873262 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04714///Thermogenesis+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0014823///response to activity+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031667///response to nutrient levels+++GO:0035690///cellular response to drug+++GO:0046326///positive regulation of glucose import+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071333///cellular response to glucose stimulus+++GO:0071377///cellular response to glucagon stimulus+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0072577///endothelial cell apoptotic process+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901215///negative regulation of neuron death+++GO:1904640///response to methionine+++GO:2000352///negative regulation of endothelial cell apoptotic process 56637 56637 'Gsk3b' mRNA 5255 4985 5052 38.96 36.39 40.73 26.72 25.8 26.67 38.69333333 26.39666667 4065 3855 3976 5097.333333 3965.333333 7.25E-10 -0.375164882 "01521///EGFR tyrosine kinase inhibitor resistance+++04012///ErbB signaling pathway+++04062///Chemokine signaling pathway+++04110///Cell cycle+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04360///Axon guidance+++04390///Hippo signaling pathway+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04657///IL-17 signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04711///Circadian rhythm - fly+++04722///Neurotrophin signaling pathway+++04728///Dopaminergic synapse+++04910///Insulin signaling pathway+++04916///Melanogenesis+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04936///Alcoholic liver disease+++05010///Alzheimer disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05135///Yersinia infection+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05200///Pathways in cancer+++05210///Colorectal cancer+++05213///Endometrial cancer+++05215///Prostate cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030877///beta-catenin destruction complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043227///membrane-bounded organelle+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0048471///perinuclear region of cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex+++GO:1990909///Wnt signalosome GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0034452///dynactin binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0048156///tau protein binding+++GO:0050321///tau-protein kinase activity+++GO:0051059///NF-kappaB binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070840///dynein complex binding GO:0000320///re-entry into mitotic cell cycle+++GO:0001558///regulation of cell growth+++GO:0001837///epithelial to mesenchymal transition+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006468///protein phosphorylation+++GO:0006611///protein export from nucleus+++GO:0006983///ER overload response+++GO:0007010///cytoskeleton organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007520///myoblast fusion+++GO:0007623///circadian rhythm+++GO:0008286///insulin receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0009968///negative regulation of signal transduction+++GO:0010043///response to zinc ion+++GO:0010508///positive regulation of autophagy+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010628///positive regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010822///positive regulation of mitochondrion organization+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0010975///regulation of neuron projection development+++GO:0010977///negative regulation of neuron projection development+++GO:0014043///negative regulation of neuron maturation+++GO:0014902///myotube differentiation+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0021766///hippocampus development+++GO:0030010///establishment of cell polarity+++GO:0030011///maintenance of cell polarity+++GO:0030154///cell differentiation+++GO:0030516///regulation of axon extension+++GO:0031175///neuron projection development+++GO:0031333///negative regulation of protein complex assembly+++GO:0031334///positive regulation of protein complex assembly+++GO:0032007///negative regulation of TOR signaling+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032886///regulation of microtubule-based process+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0035372///protein localization to microtubule+++GO:0035556///intracellular signal transduction+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0035733///hepatic stellate cell activation+++GO:0036016///cellular response to interleukin-3+++GO:0042752///regulation of circadian rhythm+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0044027///hypermethylation of CpG island+++GO:0045444///fat cell differentiation+++GO:0045667///regulation of osteoblast differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045773///positive regulation of axon extension+++GO:0045886///negative regulation of synaptic growth at neuromuscular junction+++GO:0045887///positive regulation of synaptic growth at neuromuscular junction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0046849///bone remodeling+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048511///rhythmic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0060070///canonical Wnt signaling pathway+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071109///superior temporal gyrus development+++GO:0071260///cellular response to mechanical stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090290///positive regulation of osteoclast proliferation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097284///hepatocyte apoptotic process+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0106027///neuron projection organization+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:1901984///negative regulation of protein acetylation+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904339///negative regulation of dopaminergic neuron differentiation+++GO:1904646///cellular response to amyloid-beta+++GO:1904780///negative regulation of protein localization to centrosome+++GO:1904781///positive regulation of protein localization to centrosome+++GO:2000171///negative regulation of dendrite development+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2000738///positive regulation of stem cell differentiation+++GO:2001223///negative regulation of neuron migration 56642 56642 'Ankrd2' mRNA 5 7 5 0.28 0.39 0.3 0.44 0.7 0.3 0.323333333 0.48 9 14 6 5.666666667 9.666666667 0.475696797 0.765596162 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0031674///I band+++GO:0043231///intracellular membrane-bounded organelle GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0031432///titin binding+++GO:0043422///protein kinase B binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001817///regulation of cytokine production+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010832///negative regulation of myotube differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0035994///response to muscle stretch+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0045662///negative regulation of myoblast differentiation+++GO:1902253///regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:2000291///regulation of myoblast proliferation 56643 56643 'Slc15a1' mRNA 4 6 1.76 0.07 0.1 0.03 0.27 0.3 0.24 0.066666667 0.27 18 19 15 3.92 17.33333333 0.010077529 2.245729673 04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005427///proton-dependent oligopeptide secondary active transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015333///peptide:proton symporter activity+++GO:0016248///channel inhibitor activity+++GO:0022857///transmembrane transporter activity+++GO:0035673///oligopeptide transmembrane transporter activity+++GO:0071916///dipeptide transmembrane transporter activity GO:0006857///oligopeptide transport+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0035672///oligopeptide transmembrane transport+++GO:0051956///negative regulation of amino acid transport+++GO:0055085///transmembrane transport+++GO:0140206///dipeptide import across plasma membrane+++GO:1902600///proton transmembrane transport 56644 56644 'Clec7a' mRNA 67 63 54 1.76 1.63 1.51 20.87 21.91 22.38 1.633333333 21.72 913 936 948 61.33333333 932.3333333 1.43E-148 3.916682763 04145///Phagosome+++04613///Neutrophil extracellular trap formation+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001872///(1->3)-beta-D-glucan binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038187///pattern recognition receptor activity+++GO:0046872///metal ion binding "GO:0001775///cell activation+++GO:0001878///response to yeast+++GO:0001879///detection of yeast+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002366///leukocyte activation involved in immune response+++GO:0002376///immune system process+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0002732///positive regulation of dendritic cell cytokine production+++GO:0006910///phagocytosis, recognition+++GO:0006954///inflammatory response+++GO:0008037///cell recognition+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0016046///detection of fungus+++GO:0030335///positive regulation of cell migration+++GO:0031334///positive regulation of protein complex assembly+++GO:0032491///detection of molecule of fungal origin+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032747///positive regulation of interleukin-23 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032930///positive regulation of superoxide anion generation+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050766///positive regulation of phagocytosis+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051251///positive regulation of lymphocyte activation+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0060267///positive regulation of respiratory burst+++GO:0061760///antifungal innate immune response+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0071226///cellular response to molecule of fungal origin+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0090303///positive regulation of wound healing+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1903431///positive regulation of cell maturation+++GO:2000318///positive regulation of T-helper 17 type immune response" 56690 56690 'Mlycd' mRNA 602 655 193 16.15 17.24 5.87 4.5 5.76 6.66 13.08666667 5.64 196 242 285 483.3333333 241 0.086324161 -0.989120254 00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++04146///Peroxisome+++04152///AMPK signaling pathway+++04936///Alcoholic liver disease GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0042802///identical protein binding+++GO:0050080///malonyl-CoA decarboxylase activity GO:0002931///response to ischemia+++GO:0006085///acetyl-CoA biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0010906///regulation of glucose metabolic process+++GO:0019395///fatty acid oxidation+++GO:0031998///regulation of fatty acid beta-oxidation+++GO:0046320///regulation of fatty acid oxidation+++GO:0046321///positive regulation of fatty acid oxidation+++GO:2001294///malonyl-CoA catabolic process 56692 56692 'Lamtor3' mRNA 1131 1130 1008 54.46 53.72 51.5 69.72 68.17 70.1 53.22666667 69.33 1662 1585 1616 1089.666667 1621 1.34E-13 0.562718993 04010///MAPK signaling pathway+++04150///mTOR signaling pathway GO:0005768///endosome+++GO:0005770///late endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0071986///Ragulator complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019209///kinase activator activity+++GO:0060090///molecular adaptor activity GO:0000186///activation of MAPKK activity+++GO:0032006///regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0033674///positive regulation of kinase activity+++GO:0034613///cellular protein localization+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity+++GO:0071230///cellular response to amino acid stimulus+++GO:1902414///protein localization to cell junction 56693 56693 'Crtap' mRNA 513 515 456 17.36 17.18 16.37 39.25 37.05 41.53 16.97 39.27666667 1333 1228 1365 494.6666667 1308.666667 9.52E-52 1.393193848 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0005518///collagen binding GO:0007283///spermatogenesis+++GO:0018400///peptidyl-proline hydroxylation to 3-hydroxy-L-proline+++GO:0030199///collagen fibril organization+++GO:0050821///protein stabilization+++GO:0061077///chaperone-mediated protein folding+++GO:1901874///negative regulation of post-translational protein modification 56695 56695 'Pnkd' mRNA 2440 2509 2439 120.54 123.66 130.53 115.03 119.36 126.99 124.91 120.46 2230 2104 2221 2462.666667 2185 0.009596956 -0.185050909 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane GO:0004416///hydroxyacylglutathione hydrolase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0019243///methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione+++GO:0032225///regulation of synaptic transmission, dopaminergic+++GO:0042053///regulation of dopamine metabolic process+++GO:0046929///negative regulation of neurotransmitter secretion+++GO:0050884///neuromuscular process controlling posture" 56696 56696 'Gpr132' mRNA 2 9 6 0.05 0.2 0.15 1.09 1.05 1.06 0.133333333 1.066666667 55 53 52 5.666666667 53.33333333 8.19E-09 3.223588998 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle 56697 56697 'Akap10' mRNA 691.33 629 734 6.34 5.71 7.58 7.89 6.56 7.07 6.543333333 7.173333333 851.08 706.82 735 684.7766667 764.3 0.302275824 0.141253964 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0051018///protein kinase A binding GO:0008104///protein localization 56698 56698 'Phax' mRNA 928 930 892 28.51 28.11 28.87 27.02 27.78 25.49 28.49666667 26.76333333 1014.24 1018.23 927 916.6666667 986.49 0.387646916 0.094107045 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0015030///Cajal body+++GO:0043025///neuronal cell body+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0015643///toxic substance binding+++GO:0140262///mRNA cap binding complex binding GO:0006408///snRNA export from nucleus+++GO:0015031///protein transport+++GO:0043489///RNA stabilization 56699 56699 'Cdc42ep4' mRNA 4423 4666 4325 81.56 84.55 84.56 78.09 79.55 75.29 83.55666667 77.64333333 4876 4859 4572 4471.333333 4769 0.227188247 0.081691365 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0012505///endomembrane system+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0045335///phagocytic vesicle GO:0005515///protein binding GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0071346///cellular response to interferon-gamma 56700 56700 'Glmp' mRNA 3725 3883 3622 142.69 146.69 147.19 211.44 232.33 222.89 145.5233333 222.22 6341 6799 6467 3743.333333 6535.666667 3.06E-39 0.793498475 GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0061462///protein localization to lysosome 56702 56702 'H1f5' mRNA 3 14 13 0.26 1.19 1.19 7.74 8.49 9.5 0.88 8.576666667 103 110 122 10 111.6666667 7.41E-17 3.467529932 GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0042826///histone deacetylase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0007517///muscle organ development+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0030307///positive regulation of cell growth+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:0050821///protein stabilization+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0071169///establishment of protein localization to chromatin 56703 56703 'Pigo' mRNA 974 976 1122 13.59 13.3 16.54 8.44 8.08 8.92 14.47666667 8.48 702 650 695 1024 682.3333333 5.49E-08 -0.602152059 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0051377///mannose-ethanolamine phosphotransferase activity" GO:0006506///GPI anchor biosynthetic process 56705 56705 'Ranbp9' mRNA 336.36 327.18 301 6.02 5.76 5.72 6.8 6.29 6.35 5.833333333 6.48 436.79 395.09 395.42 321.5133333 409.1 0.015522268 0.335613643 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016604///nuclear body GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding GO:0007010///cytoskeleton organization+++GO:0007166///cell surface receptor signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902993///positive regulation of amyloid precursor protein catabolic process 56706 56706 'Ccnl1' mRNA 1800.39 1888 1846 33.54 35.24 38.69 39.26 40.42 36.71 35.82333333 38.79666667 2365.07 2336.84 2163.66 1844.796667 2288.523333 8.69E-05 0.298151133 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008023///transcription elongation factor complex+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006396///RNA processing" 56707 56707 'Zfp111' mRNA 720.79 699.35 659.39 3.93 3.75 3.86 2.61 2.53 2.5 3.846666667 2.546666667 546.4 508.74 515.46 693.1766667 523.5333333 9.60E-05 -0.416777636 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 56708 56708 'Clcf1' mRNA 60 61 55 1.85 1.87 1.8 3.86 3.56 3.19 1.84 3.536666667 144 129 115 58.66666667 129.3333333 1.27E-05 1.128933095 04060///Cytokine-cytokine receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0097058///CRLF-CLCF1 complex+++GO:0097059///CNTFR-CLCF1 complex GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0005515///protein binding GO:0002639///positive regulation of immunoglobulin production+++GO:0002830///positive regulation of type 2 immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0030183///B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048295///positive regulation of isotype switching to IgE isotypes+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0050727///regulation of inflammatory response+++GO:0051466///positive regulation of corticotropin-releasing hormone secretion+++GO:0051896///regulation of protein kinase B signaling+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:2000672///negative regulation of motor neuron apoptotic process 56709 56709 'Dnajb12' mRNA 984 936 848 17.76 16.6 16.21 14.09 12.83 12.53 16.85666667 13.15 900 800 776 922.6666667 825.3333333 0.103019467 -0.171804548 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031965///nuclear membrane GO:0030544///Hsp70 protein binding GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0034622///cellular protein-containing complex assembly+++GO:0036503///ERAD pathway+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071218///cellular response to misfolded protein 56710 56710 'Brinp1' mRNA 32 33 39 0.52 0.53 0.67 0 0.06 0.03 0.573333333 0.03 0 4 2 34.66666667 2 4.91E-07 -4.127037558 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0001662///behavioral fear response+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007614///short-term memory+++GO:0008219///cell death+++GO:0035176///social behavior+++GO:0035640///exploration behavior+++GO:0042711///maternal behavior+++GO:0045666///positive regulation of neuron differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0050768///negative regulation of neurogenesis+++GO:0051726///regulation of cell cycle+++GO:0071300///cellular response to retinoic acid+++GO:0071625///vocalization behavior 56711 56711 'Plag1' mRNA 406.59 327.31 310.18 2.95 2.43 2.56 1.31 1.04 1.61 2.646666667 1.32 199.42 162.02 219.94 348.0266667 193.7933333 7.33E-07 -0.857089406 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0022612///gland morphogenesis+++GO:0035264///multicellular organism growth+++GO:0035265///organ growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060736///prostate gland growth" 56715 56715 'Rabgef1' mRNA 971 958 983 20.22 19.69 21.71 16.04 14.27 15.31 20.54 15.20666667 886 771 821 970.6666667 826 0.014870279 -0.246844535 GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0055037///recycling endosome GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001933///negative regulation of protein phosphorylation+++GO:0002686///negative regulation of leukocyte migration+++GO:0006612///protein targeting to membrane+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016567///protein ubiquitination+++GO:0032715///negative regulation of interleukin-6 production+++GO:0033004///negative regulation of mast cell activation+++GO:0043305///negative regulation of mast cell degranulation+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0050728///negative regulation of inflammatory response+++GO:0050790///regulation of catalytic activity+++GO:0060368///regulation of Fc receptor mediated stimulatory signaling pathway+++GO:1900235///negative regulation of Kit signaling pathway+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin+++GO:2001214///positive regulation of vasculogenesis 56716 56716 'Mlst8' mRNA 1386.14 1422.68 1360.61 23.39 23.46 24.12 14.85 14.24 14.21 23.65666667 14.43333333 1029.2 969.22 949.78 1389.81 982.7333333 3.95E-10 -0.512296655 04136///Autophagy - other+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04714///Thermogenesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031931///TORC1 complex+++GO:0031932///TORC2 complex GO:0043539///protein serine/threonine kinase activator activity GO:0030838///positive regulation of actin filament polymerization+++GO:0031929///TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0038202///TORC1 signaling+++GO:0043087///regulation of GTPase activity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity 56717 56717 'Mtor' mRNA 1099 1106 953 6.73 6.64 6.19 5.85 6.04 6.03 6.52 5.973333333 1103 1112 1101 1052.666667 1105.333333 0.573249889 0.061307542 "01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04072///Phospholipase D signaling pathway+++04136///Autophagy - other+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04613///Neutrophil extracellular trap formation+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04919///Thyroid hormone signaling pathway+++04920///Adipocytokine signaling pathway+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04935///Growth hormone synthesis, secretion and action+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05214///Glioma+++05215///Prostate cancer+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy" GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016605///PML body+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031931///TORC1 complex+++GO:0031932///TORC2 complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0045335///phagocytic vesicle+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0000166///nucleotide binding+++GO:0001002///RNA polymerase III type 1 promoter sequence-specific DNA binding+++GO:0001003///RNA polymerase III type 2 promoter sequence-specific DNA binding+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0001156///TFIIIC-class transcription factor complex binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0043022///ribosome binding+++GO:0044877///protein-containing complex binding+++GO:0045182///translation regulator activity+++GO:0051219///phosphoprotein binding "GO:0001558///regulation of cell growth+++GO:0001932///regulation of protein phosphorylation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0003007///heart morphogenesis+++GO:0003179///heart valve morphogenesis+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0006109///regulation of carbohydrate metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0007040///lysosome organization+++GO:0007281///germ cell development+++GO:0007420///brain development+++GO:0007569///cell aging+++GO:0007584///response to nutrient+++GO:0007616///long-term memory+++GO:0008361///regulation of cell size+++GO:0008542///visual learning+++GO:0009267///cellular response to starvation+++GO:0009408///response to heat+++GO:0009791///post-embryonic development+++GO:0010506///regulation of autophagy+++GO:0010507///negative regulation of autophagy+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010831///positive regulation of myotube differentiation+++GO:0010942///positive regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0014042///positive regulation of neuron maturation+++GO:0014736///negative regulation of muscle atrophy+++GO:0014823///response to activity+++GO:0016242///negative regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019228///neuronal action potential+++GO:0021510///spinal cord development+++GO:0030030///cell projection organization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031529///ruffle organization+++GO:0031641///regulation of myelination+++GO:0031667///response to nutrient levels+++GO:0031669///cellular response to nutrient levels+++GO:0031929///TOR signaling+++GO:0031998///regulation of fatty acid beta-oxidation+++GO:0032095///regulation of response to food+++GO:0032868///response to insulin+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034198///cellular response to amino acid starvation+++GO:0035176///social behavior+++GO:0035264///multicellular organism growth+++GO:0038202///TORC1 signaling+++GO:0042060///wound healing+++GO:0042220///response to cocaine+++GO:0042752///regulation of circadian rhythm+++GO:0043087///regulation of GTPase activity+++GO:0043200///response to amino acid+++GO:0043278///response to morphine+++GO:0043610///regulation of carbohydrate utilization+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045670///regulation of osteoclast differentiation+++GO:0045727///positive regulation of translation+++GO:0045792///negative regulation of cell size+++GO:0045859///regulation of protein kinase activity+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0046777///protein autophosphorylation+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0048255///mRNA stabilization+++GO:0048266///behavioral response to pain+++GO:0048511///rhythmic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0048738///cardiac muscle tissue development+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050769///positive regulation of neurogenesis+++GO:0050882///voluntary musculoskeletal movement+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051549///positive regulation of keratinocyte migration+++GO:0051647///nucleus localization+++GO:0051896///regulation of protein kinase B signaling+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055006///cardiac cell development+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060135///maternal process involved in female pregnancy+++GO:0060252///positive regulation of glial cell proliferation+++GO:0060999///positive regulation of dendritic spine development+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:0071456///cellular response to hypoxia+++GO:0090335///regulation of brown fat cell differentiation+++GO:0090559///regulation of membrane permeability+++GO:0099547///regulation of translation at synapse, modulating synaptic transmission+++GO:1901216///positive regulation of neuron death+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1903691///positive regulation of wound healing, spreading of epidermal cells+++GO:1904000///positive regulation of eating behavior+++GO:1904056///positive regulation of cholangiocyte proliferation+++GO:1904058///positive regulation of sensory perception of pain+++GO:1904059///regulation of locomotor rhythm+++GO:1904193///negative regulation of cholangiocyte apoptotic process+++GO:1904197///positive regulation of granulosa cell proliferation+++GO:1904206///positive regulation of skeletal muscle hypertrophy+++GO:1904213///negative regulation of iodide transmembrane transport+++GO:1990253///cellular response to leucine starvation" 56720 56720 'Tdo2' mRNA 0 3 4 0 0.11 0.15 0.06 0.03 0.22 0.086666667 0.103333333 2 1 7 2.333333333 3.333333333 0.828240694 0.485257708 00380///Tryptophan metabolism+++01240///Biosynthesis of cofactors "GO:0004833///tryptophan 2,3-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016597///amino acid binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006568///tryptophan metabolic process+++GO:0006569///tryptophan catabolic process+++GO:0019441///tryptophan catabolic process to kynurenine+++GO:0019442///tryptophan catabolic process to acetyl-CoA+++GO:0051289///protein homotetramerization+++GO:1904842///response to nitroglycerin 56722 56722 'Litaf' mRNA 4330 4429 4248 108.97 109.87 113.59 242.03 244.67 241.74 110.81 242.8133333 11044 10903 10680 4335.666667 10875.66667 1.65E-142 1.314955608 04142///Lysosome GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098559///cytoplasmic side of early endosome membrane+++GO:0098560///cytoplasmic side of late endosome membrane+++GO:0098574///cytoplasmic side of lysosomal membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0050699///WW domain binding" GO:0001817///regulation of cytokine production+++GO:0007568///aging+++GO:0032496///response to lipopolysaccharide+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 56724 56724 'Cript' mRNA 1240 1273 1264 65.35 66.27 70.68 71.01 69.47 74.16 67.43333333 71.54666667 1546 1475 1561 1259 1527.333333 0.00133233 0.266021773 GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0045202///synapse GO:0008017///microtubule binding+++GO:0030165///PDZ domain binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding GO:0031122///cytoplasmic microtubule organization+++GO:0035372///protein localization to microtubule+++GO:0045184///establishment of protein localization+++GO:1902897///regulation of postsynaptic density protein 95 clustering 56726 56726 'Sh3bgrl' mRNA 4719 4856 4478 91.77 92.95 92.38 132.83 125.54 130.8 92.36666667 129.7233333 7858 7253 7492 4684.333333 7534.333333 2.24E-39 0.674093283 GO:0003674///molecular_function+++GO:0017124///SH3 domain binding GO:0008150///biological_process 56727 56727 'Miox' mRNA 1 1 0 0.06 0.06 0 0 0 0 0.04 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 00053///Ascorbate and aldarate metabolism+++00562///Inositol phosphate metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0016234///inclusion body "GO:0004033///aldo-keto reductase (NADP) activity+++GO:0005506///iron ion binding+++GO:0008199///ferric iron binding+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0016701///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen+++GO:0046872///metal ion binding+++GO:0050113///inositol oxygenase activity+++GO:0050661///NADP binding" GO:0019310///inositol catabolic process 56734 56734 'Tulp2' mRNA 99.51 111.59 134.04 1.92 2.26 2.78 2.24 1.1 1.77 2.32 1.703333333 119.99 67.01 96.33 115.0466667 94.44333333 0.339741364 -0.308841487 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005929///cilium GO:0008081///phosphoric diester hydrolase activity+++GO:0044877///protein-containing complex binding GO:0061512///protein localization to cilium 56736 56736 'Rnf14' mRNA 1668 1639 1529 30.34 29.21 30.45 35.6 33.23 34.96 30 34.59666667 2217 2041 2125 1612 2127.666667 2.33E-08 0.389039851 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0019787///ubiquitin-like protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060765///regulation of androgen receptor signaling pathway" 56737 56737 'Alg2' mRNA 2821 3254 2946 50.66 57.52 56.15 36.73 38.13 36.75 54.77666667 37.20333333 2353 2386 2279 3007 2339.333333 3.54E-07 -0.373485117 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding+++GO:0048306///calcium-dependent protein binding+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity" GO:0006486///protein glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0051592///response to calcium ion 56738 56738 'Mocs1' mRNA 169 183 140 3.72 4.08 3.22 2.59 2.46 2.89 3.673333333 2.646666667 135 125 146 164 135.3333333 0.217402891 -0.284933309 00790///Folate biosynthesis+++01240///Biosynthesis of cofactors GO:0005829///cytosol+++GO:0019008///molybdopterin synthase complex "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0061798///GTP 3',8'-cyclase activity+++GO:0061799///cyclic pyranopterin monophosphate synthase activity" GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0032324///molybdopterin cofactor biosynthetic process 56739 56739 'Rec8' mRNA 82 83 77 2.3 2.26 2.26 0.71 0.67 0.88 2.273333333 0.753333333 28 27 35 80.66666667 30 2.17E-05 -1.437705461 04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0008278///cohesin complex+++GO:0030893///meiotic cohesin complex+++GO:0034990///nuclear mitotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex" GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0000724///double-strand break repair via homologous recombination+++GO:0001556///oocyte maturation+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007141///male meiosis I+++GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0051177///meiotic sister chromatid cohesion+++GO:0051321///meiotic cell cycle+++GO:0072520///seminiferous tubule development+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange 56741 56741 'Igdcc4' mRNA 420 561 404 3.57 4.68 3.65 3.38 3.78 3.28 3.966666667 3.48 457 499 430 461.6666667 462 0.982574856 -0.005582012 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0098609///cell-cell adhesion 56742 56742 'Psrc1' mRNA 18 14 16 0.6 0.46 0.57 5.06 5.87 6.22 0.543333333 5.716666667 175 198 208 16 193.6666667 5.97E-32 3.587218087 GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody GO:0005515///protein binding+++GO:0008017///microtubule binding "GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0009987///cellular process+++GO:0030308///negative regulation of cell growth+++GO:0031116///positive regulation of microtubule polymerization+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization" 56743 56743 'Lat2' mRNA 102 104 118 3.1 2.99 4.17 46.19 45.95 44.68 3.42 45.60666667 1471 1455 1415 108 1447 3.19E-206 3.73112423 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0042169///SH2 domain binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002764///immune response-regulating signaling pathway+++GO:0019722///calcium-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0042113///B cell activation+++GO:0043303///mast cell degranulation+++GO:0050853///B cell receptor signaling pathway 56744 56744 'Pf4' mRNA 113 118 161 14.84 15.44 22.45 351.97 384.26 358.37 17.57666667 364.8666667 3056 3242 2998 130.6666667 3098.666667 0 4.552809052 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031091///platelet alpha granule+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0008201///heparin binding+++GO:0045236///CXCR chemokine receptor binding+++GO:0048248///CXCR3 chemokine receptor binding GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030168///platelet activation+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042127///regulation of cell proliferation+++GO:0042832///defense response to protozoan+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051873///killing by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0065003///protein-containing complex assembly+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 56745 56745 'C1qtnf1' mRNA 254 225 240 3.11 2.7 3.11 22.16 21.35 21.86 2.973333333 21.79 2093 1979 2005 239.6666667 2025.666667 1.64E-227 3.066940875 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0042802///identical protein binding GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010544///negative regulation of platelet activation+++GO:0010628///positive regulation of gene expression+++GO:0010906///regulation of glucose metabolic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0090331///negative regulation of platelet aggregation+++GO:2000860///positive regulation of aldosterone secretion 56747 56747 'Sez6l' mRNA 17 15 8 0.14 0.12 0.06 0.04 0.06 0.01 0.106666667 0.036666667 5 8 2 13.33333333 5 0.134705383 -1.412038328 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0008344///adult locomotory behavior+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0060074///synapse maturation+++GO:0090036///regulation of protein kinase C signaling 56748 56748 'Nfu1' mRNA 617.81 656 672.98 40.3 42.71 46.89 51 52.63 49.8 43.3 51.14333333 883 892 834 648.93 869.6666667 1.10E-04 0.410407769 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0016226///iron-sulfur cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer 56749 56749 'Dhodh' mRNA 463 519 535 11.61 12.97 14.09 11.28 11.23 10.45 12.89 10.98666667 511 501 462 505.6666667 491.3333333 0.749296088 -0.055763004 00240///Pyrimidine metabolism+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body "GO:0003824///catalytic activity+++GO:0004151///dihydroorotase activity+++GO:0004152///dihydroorotate dehydrogenase activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0048038///quinone binding+++GO:0048039///ubiquinone binding" GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006222///UMP biosynthetic process+++GO:0006225///UDP biosynthetic process+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0009220///pyrimidine ribonucleotide biosynthetic process+++GO:0014070///response to organic cyclic compound+++GO:0031000///response to caffeine+++GO:0042493///response to drug+++GO:0042594///response to starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0044205///'de novo' UMP biosynthetic process+++GO:0090140///regulation of mitochondrial fission+++GO:1903576///response to L-arginine 56752 56752 'Aldh9a1' mRNA 1917 1992 1838 37.08 37.98 37.69 30.97 32.6 31.37 37.58333333 31.64666667 1838 1887 1802 1915.666667 1842.333333 0.438305085 -0.067028476 "00010///Glycolysis / Gluconeogenesis+++00053///Ascorbate and aldarate metabolism+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++04936///Alcoholic liver disease" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0019145///aminobutyraldehyde dehydrogenase activity+++GO:0042802///identical protein binding+++GO:0043176///amine binding+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity+++GO:0047105///4-trimethylammoniobutyraldehyde dehydrogenase activity+++GO:0051287///NAD binding" GO:0006081///cellular aldehyde metabolic process+++GO:0009437///carnitine metabolic process+++GO:0042136///neurotransmitter biosynthetic process+++GO:0045329///carnitine biosynthetic process+++GO:0051289///protein homotetramerization 56753 56753 'Tacstd2' mRNA 213 208 209 6.98 6.72 7.26 22 21.2 22.94 6.986666667 22.04666667 772 726 779 210 759 6.39E-53 1.841519036 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane GO:0010633///negative regulation of epithelial cell migration+++GO:0050678///regulation of epithelial cell proliferation+++GO:0051497///negative regulation of stress fiber assembly+++GO:0060675///ureteric bud morphogenesis+++GO:0090191///negative regulation of branching involved in ureteric bud morphogenesis+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1900028///negative regulation of ruffle assembly+++GO:2000146///negative regulation of cell motility+++GO:2000738///positive regulation of stem cell differentiation 56758 56758 'Mbnl1' mRNA 2091 2293 2069 20.65 22.22 21.88 29.99 29.21 31.38 21.58333333 30.19333333 3440 3201 3422 2151 3354.333333 2.54E-22 0.629668164 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule GO:0001069///regulatory region RNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0046872///metal ion binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0007519///skeletal muscle tissue development+++GO:0008380///RNA splicing+++GO:0030326///embryonic limb morphogenesis+++GO:0043484///regulation of RNA splicing+++GO:0045445///myoblast differentiation" 56760 56760 'Clec1b' mRNA 1 11 6 0.06 0.58 0.37 0.15 0.19 0.24 0.336666667 0.193333333 3 4 5 6 4 0.702622628 -0.589962714 04625///C-type lectin receptor signaling pathway GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0030246///carbohydrate binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0030220///platelet formation 56771 56771 'Med20' mRNA 1131.62 1190.38 1157.25 27.99 29.81 29.84 26.02 23.07 23.27 29.21333333 24.12 1171.26 973.23 1013.21 1159.75 1052.566667 0.135500198 -0.153607342 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0035914///skeletal muscle cell differentiation 56772 56772 'Mllt11' mRNA 222.87 228.21 191.79 5.17 5.08 5 5.25 5.3 5.22 5.083333333 5.256666667 244.08 233.64 213.15 214.29 230.29 0.660279875 0.096796395 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003674///molecular_function "GO:0008150///biological_process+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway" 56773 56773 'Chst5' mRNA 3438 3518 3607 101.53 102.37 113 69.57 70.45 70.63 105.6333333 70.21666667 2708 2677 2661 3521 2682 4.86E-09 -0.406173013 00533///Glycosaminoglycan biosynthesis - keratan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0018146///keratan sulfate biosynthetic process 56774 56774 'Slc6a14' mRNA 1156 1216 1195 18.33 18.97 20.1 12.9 12.22 13.48 19.13333333 12.86666667 936 866 947 1189 916.3333333 1.85E-05 -0.388746813 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0005275///amine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022858///alanine transmembrane transporter activity GO:0006865///amino acid transport+++GO:0009636///response to toxic substance+++GO:0015837///amine transport+++GO:0032328///alanine transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane 56784 56784 'Ralgapa1' mRNA 1487 1576 1414 11.75 11.9 11.35 7.65 6.61 7.55 11.66666667 7.27 1164 985 1164 1492.333333 1104.333333 3.01E-07 -0.445997395 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity" 56786 56786 'Tmem9b' mRNA 2463 2727 2522 84.96 92.73 92.29 90.66 89.32 87.86 89.99333333 89.28 3020 2904 2832 2570.666667 2918.666667 0.01674452 0.171265232 GO:0005575///cellular_component+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane 56787 56787 'Ascl3' mRNA 2 7 1 0.2 0.7 0.11 0.09 0.18 0.18 0.336666667 0.15 1 2 2 3.333333333 1.666666667 0.626076944 -0.980791992 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 56788 56788 'Scube2' mRNA 241 203 230 3.67 3.04 3.72 1.63 2.02 1.78 3.476666667 1.81 123 149 130 224.6666667 134 1.47E-04 -0.757860125 04340///Hedgehog signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0019897///extrinsic component of plasma membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0097108///hedgehog family protein binding GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:1902732///positive regulation of chondrocyte proliferation 56790 56790 'Supt20' mRNA 1089 1082 1018 20.23 20.17 20.24 14.76 13.19 13.99 20.21333333 13.98 914 795 826 1063 845 1.92E-04 -0.343280235 04140///Autophagy - animal GO:0000124///SAGA complex+++GO:0070461///SAGA-type complex GO:0003712///transcription coregulator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II" 56791 56791 'Ube2l6' mRNA 986.92 1063.89 1102.57 42.57 45.28 50.46 92.53 99.6 91.26 46.10333333 94.46333333 2463.38 2586.74 2349.99 1051.126667 2466.703333 6.44E-46 1.217878993 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0019787///ubiquitin-like protein transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042296///ISG15 transferase activity+++GO:0043130///ubiquitin binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0032020///ISG15-protein conjugation 56792 56792 'Stap1' mRNA 7 9 7 0.35 0.57 0.43 4.11 3.35 3.78 0.45 3.746666667 92 75 80 7.666666667 82.33333333 2.88E-14 3.41323186 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0001784///phosphotyrosine residue binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005157///macrophage colony-stimulating factor receptor binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0030971///receptor tyrosine kinase binding+++GO:0035591///signaling adaptor activity" "GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0009617///response to bacterium+++GO:0010628///positive regulation of gene expression+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0030099///myeloid cell differentiation+++GO:0042326///negative regulation of phosphorylation+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0071222///cellular response to lipopolysaccharide+++GO:1900028///negative regulation of ruffle assembly+++GO:1902227///negative regulation of macrophage colony-stimulating factor signaling pathway+++GO:1903980///positive regulation of microglial cell activation+++GO:1903997///positive regulation of non-membrane spanning protein tyrosine kinase activity+++GO:1904140///negative regulation of microglial cell migration+++GO:1904151///positive regulation of microglial cell mediated cytotoxicity+++GO:2000251///positive regulation of actin cytoskeleton reorganization" 56794 56794 'Hacl1' mRNA 633 641 614 12.69 12.7 12.96 7.54 8.49 7.58 12.78333333 7.87 433 474 423 629.3333333 443.3333333 9.83E-06 -0.516362221 04146///Peroxisome GO:0005654///nucleoplasm+++GO:0005777///peroxisome+++GO:0043231///intracellular membrane-bounded organelle GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0030976///thiamine pyrophosphate binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001561///fatty acid alpha-oxidation+++GO:0006625///protein targeting to peroxisome+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0097089///methyl-branched fatty acid metabolic process+++GO:1903512///phytanic acid metabolic process 56795 56795 'Arl10' mRNA 908.89 925 787 15.46 15.89 14.6 14.01 16.79 16.13 15.31666667 15.64333333 871 1018 975.27 873.63 954.7566667 0.309772789 0.120933136 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008150///biological_process 56805 56805 'Zbtb33' mRNA 95.12 94.85 98.31 0.99 0.97 1.09 1.47 1.2 1.03 1.016666667 1.233333333 159.48 129.09 108.91 96.09333333 132.4933333 0.087725583 0.449126915 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008327///methyl-CpG binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016055///Wnt signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated" 56807 56807 'Scamp5' mRNA 1625.93 1555 1641 23.07 20.76 24.46 19.75 18.83 17.85 22.76333333 18.81 1549 1385.01 1331.72 1607.31 1421.91 0.038987513 -0.191355901 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane GO:0044877///protein-containing complex binding GO:0001819///positive regulation of cytokine production+++GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045806///negative regulation of endocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:1900242///regulation of synaptic vesicle endocytosis 56808 56808 'Cacna2d2' mRNA 78 61 34 0.75 0.58 0.35 0.27 0.15 0.17 0.56 0.196666667 32 18 20 57.66666667 23.33333333 0.003818983 -1.309086941 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0007528///neuromuscular junction development+++GO:0008016///regulation of heart contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0040014///regulation of multicellular organism growth+++GO:0046622///positive regulation of organ growth+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development+++GO:0060024///rhythmic synaptic transmission+++GO:0070588///calcium ion transmembrane transport 56809 56809 'Gmeb1' mRNA 771.8 818.37 742.32 5.49 5.42 5.48 6.85 6.03 6.63 5.463333333 6.503333333 1101.14 923.42 1010.42 777.4966667 1011.66 1.54E-04 0.368126288 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051008///Hsp27 protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 56811 56811 'Dkk2' mRNA 110 139 106 1.61 2 1.64 0.14 0.14 0.17 1.75 0.15 11 11 13 118.3333333 11.66666667 1.49E-19 -3.350486867 04310///Wnt signaling pathway+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0039706///co-receptor binding+++GO:0048019///receptor antagonist activity GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 56812 56812 'Dnajb2' mRNA 3634 3755 3462 98.76 100.88 100.36 41.33 43.29 40.93 100 41.85 1894 1918 1779 3617 1863.666667 9.52E-52 -0.967528822 04141///Protein processing in endoplasmic reticulum GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016234///inclusion body+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0031965///nuclear membrane+++GO:0048471///perinuclear region of cytoplasm GO:0001671///ATPase activator activity+++GO:0030544///Hsp70 protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0070628///proteasome binding+++GO:0140036///ubiquitin-dependent protein binding GO:0008285///negative regulation of cell proliferation+++GO:0030308///negative regulation of cell growth+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031396///regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032781///positive regulation of ATPase activity+++GO:0032880///regulation of protein localization+++GO:0042026///protein refolding+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity+++GO:0061077///chaperone-mediated protein folding+++GO:0090084///negative regulation of inclusion body assembly+++GO:0090086///negative regulation of protein deubiquitination+++GO:1903644///regulation of chaperone-mediated protein folding 56838 56838 'Ccl28' mRNA 25 39 20 0.34 0.52 0.3 0.06 0.04 0.1 0.386666667 0.066666667 5 3 8 28 5.333333333 5.76E-04 -2.394425018 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway+++04672///Intestinal immune network for IgA production GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule GO:0005125///cytokine activity+++GO:0008009///chemokine activity GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006935///chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0031640///killing of cells of other organism+++GO:0051715///cytolysis in other organism+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1903237///negative regulation of leukocyte tethering or rolling 56839 56839 'Lgi1' mRNA 51 51 49 0.63 0.62 0.64 0.18 0.09 0.12 0.63 0.13 17 8 11 50.33333333 12 1.31E-05 -2.08437911 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030054///cell junction+++GO:0043083///synaptic cleft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0007411///axon guidance+++GO:0030307///positive regulation of cell growth+++GO:0031175///neuron projection development+++GO:0050806///positive regulation of synaptic transmission+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 56843 56843 'Trpm5' mRNA 12 11 13 0.15 0.14 0.17 0.04 0.05 0.04 0.153333333 0.043333333 3 4 3 12 3.333333333 0.055263632 -1.861978649 04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005267///potassium channel activity+++GO:0005272///sodium channel activity+++GO:0099604///ligand-gated calcium channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0019722///calcium-mediated signaling+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0050909///sensory perception of taste+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098655///cation transmembrane transport 56844 56844 'Tssc4' mRNA 1387.97 1495.93 1393.05 57.06 60.32 59.31 72.89 75.03 67.42 58.89666667 71.78 2689.53 2668.49 2408.21 1425.65 2588.743333 5.19E-30 0.849410592 GO:0005575///cellular_component GO:0008150///biological_process 56846 56846 'Necab3' mRNA 83 57 98 2.65 1.78 3.27 0.86 0.67 0.72 2.566666667 0.75 31 23 26 79.33333333 26.66666667 2.46E-05 -1.596487242 GO:0000137///Golgi cis cisterna+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0019538///protein metabolic process+++GO:0042984///regulation of amyloid precursor protein biosynthetic process 56847 56847 'Aldh1a3' mRNA 6677 7179 7104 106.95 113.14 120.71 48.54 46.43 47.95 113.6 47.64 3487 3258 3336 6986.666667 3360.333333 9.22E-65 -1.069670079 00830///Retinol metabolism GO:0005737///cytoplasm "GO:0001758///retinal dehydrogenase activity+++GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0042803///protein homodimerization activity+++GO:0070324///thyroid hormone binding+++GO:0070403///NAD+ binding" GO:0002072///optic cup morphogenesis involved in camera-type eye development+++GO:0002138///retinoic acid biosynthetic process+++GO:0006081///cellular aldehyde metabolic process+++GO:0007626///locomotory behavior+++GO:0021768///nucleus accumbens development+++GO:0031076///embryonic camera-type eye development+++GO:0042472///inner ear morphogenesis+++GO:0042572///retinol metabolic process+++GO:0042573///retinoic acid metabolic process+++GO:0042574///retinal metabolic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043584///nose development+++GO:0048048///embryonic eye morphogenesis+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0050885///neuromuscular process controlling balance+++GO:0051289///protein homotetramerization+++GO:0060013///righting reflex+++GO:0060166///olfactory pit development+++GO:0060324///face development+++GO:0070384///Harderian gland development 56856 56856 'Insm2' mRNA 1 2 2 0.02 0.03 0.04 0.02 0.02 0.02 0.03 0.02 1 1 1 1.666666667 1 0.781420286 -0.75364786 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010564///regulation of cell cycle process+++GO:0030182///neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 56857 56857 'Slc37a2' mRNA 96 101 84 1.18 1.22 1.09 19.36 20.46 20.07 1.163333333 19.96333333 1816 1875 1824 93.66666667 1838.333333 4.68E-280 4.285204905 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0015169///glycerol-3-phosphate transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006127///glycerophosphate shuttle+++GO:0008643///carbohydrate transport+++GO:0015712///hexose phosphate transport+++GO:0015760///glucose-6-phosphate transport+++GO:0015794///glycerol-3-phosphate transmembrane transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0055085///transmembrane transport 56860 56860 'Olfr690' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 56863 56863 'Cldn9' mRNA 19487 19972 19199 802.8 811.69 839.12 568.6 569.24 556.64 817.87 564.8266667 15852 15484 15012 19552.66667 15449.33333 1.50E-12 -0.351987496 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0001618///virus receptor activity+++GO:0005198///structural molecule activity+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0045216///cell-cell junction organization+++GO:0046718///viral entry into host cell+++GO:0070830///bicellular tight junction assembly+++GO:0120193///tight junction organization 56868 56868 'Psg23' mRNA 16.18 17.91 17.39 0.42 0.46 0.48 0.27 0.19 0.12 0.453333333 0.193333333 12.01 8.17 5 17.16 8.393333333 0.19330618 -1.017047968 GO:0005575///cellular_component GO:0043395///heparan sulfate proteoglycan binding GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0010628///positive regulation of gene expression+++GO:0030195///negative regulation of blood coagulation 56869 56869 'Zfp109' mRNA 161.64 150.83 160.81 2.09 1.8 2.29 1.1 1.07 1.05 2.06 1.073333333 97.34 89 88.04 157.76 91.46 4.19E-04 -0.795399503 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 56873 56873 'Lmbr1' mRNA 702 708 670.23 12.03 12.19 12.25 6.4 6.21 6.65 12.15666667 6.42 437 414.07 446.08 693.41 432.3833333 1.75E-10 -0.692936108 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity GO:0007165///signal transduction+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0042733///embryonic digit morphogenesis 56874 56874 'Rnf32' mRNA 366 384 353 9.26 9.34 8.99 1.76 2.14 2.69 9.196666667 2.196666667 85 91 111 367.6666667 95.66666667 6.80E-29 -1.952556988 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0016604///nuclear body GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 56876 56876 'Nsmf' mRNA 3120 3326 3385 60.61 62.69 69.86 32.45 32.06 31.66 64.38666667 32.05666667 1949 1867 1810 3277 1875.333333 1.93E-28 -0.819316704 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030863///cortical cytoskeleton+++GO:0031965///nuclear membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0097440///apical dendrite+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0048306///calcium-dependent protein binding GO:0035307///positive regulation of protein dephosphorylation+++GO:0043523///regulation of neuron apoptotic process+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048814///regulation of dendrite morphogenesis+++GO:0071230///cellular response to amino acid stimulus+++GO:0071257///cellular response to electrical stimulus+++GO:0071371///cellular response to gonadotropin stimulus+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:2001222///regulation of neuron migration+++GO:2001224///positive regulation of neuron migration 56878 56878 'Rbms1' mRNA 1314 1417 1025 26.11 28.26 20.63 43.68 48.79 51.44 25 47.97 2661 2799 2948 1252 2802.666667 4.39E-38 1.157492403 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding GO:0006260///DNA replication 57014 57014 'Htr3b' mRNA 3 1 0 0.07 0.02 0 0 0.02 0 0.03 0.006666667 0 1 0 1.333333333 0.333333333 0.613640626 -1.878270324 04726///Serotonergic synapse+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:1904602///serotonin-activated cation-selective channel complex GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0022850///serotonin-gated cation-selective channel activity+++GO:0030594///neurotransmitter receptor activity GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0007210///serotonin receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process 57028 57028 'Pdxp' mRNA 373 393 111 10.61 11.02 3.35 1.39 1.24 1.82 8.326666667 1.483333333 56 49 71 292.3333333 58.66666667 4.63E-05 -2.304617059 00750///Vitamin B6 metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030496///midbody+++GO:0031258///lamellipodium membrane+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0070938///contractile ring GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019838///growth factor binding+++GO:0031072///heat shock protein binding+++GO:0033883///pyridoxal phosphatase activity+++GO:0036424///L-phosphoserine phosphatase activity+++GO:0036425///D-phosphoserine phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0043136///glycerol-3-phosphatase activity+++GO:0046872///metal ion binding GO:0006114///glycerol biosynthetic process+++GO:0006470///protein dephosphorylation+++GO:0006650///glycerophospholipid metabolic process+++GO:0007088///regulation of mitotic nuclear division+++GO:0016311///dephosphorylation+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0031247///actin rod assembly+++GO:0032361///pyridoxal phosphate catabolic process+++GO:0032465///regulation of cytokinesis+++GO:0071318///cellular response to ATP 57080 57080 'Gtf2ird1' mRNA 1199 1205 1071 16.31 16.56 15.49 6.19 6.09 6.08 16.12 6.12 509 510 493 1158.333333 504 1.97E-39 -1.21044195 03022///Basal transcription factors+++04022///cGMP-PKG signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0009790///embryo development+++GO:0014886///transition between slow and fast fiber 57138 57138 'Slc12a5' mRNA 74 81 60 0.69 0.74 0.57 0.13 0.23 0.18 0.666666667 0.18 16 28 22 71.66666667 22 9.93E-06 -1.707118427 04727///GABAergic synapse GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032590///dendrite membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0071944///cell periphery GO:0005515///protein binding+++GO:0008519///ammonium transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006821///chloride transport+++GO:0006873///cellular ion homeostasis+++GO:0006884///cell volume homeostasis+++GO:0006971///hypotonic response+++GO:0007268///chemical synaptic transmission+++GO:0007612///learning+++GO:0009410///response to xenobiotic stimulus+++GO:0015696///ammonium transport+++GO:0030644///cellular chloride ion homeostasis+++GO:0035264///multicellular organism growth+++GO:0040040///thermosensory behavior+++GO:0042493///response to drug+++GO:0051452///intracellular pH reduction+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0060996///dendritic spine development+++GO:0071805///potassium ion transmembrane transport+++GO:0072488///ammonium transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 57170 57170 'Dolpp1' mRNA 554 574 518 13.74 14.1 13.7 10.71 11.33 10.93 13.84666667 10.99 494 511 489 548.6666667 498 0.244138081 -0.149963926 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016787///hydrolase activity+++GO:0047874///dolichyldiphosphatase activity GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0008610///lipid biosynthetic process 57230 57230 'Sap30bp' mRNA 752 795 706 20.43 21.26 20.3 17.46 18.17 17.95 20.66333333 17.86 740 751 736 751 742.3333333 0.854885182 -0.026847347 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0045111///intermediate filament cytoskeleton "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0009615///response to virus+++GO:0010942///positive regulation of cell death+++GO:0031065///positive regulation of histone deacetylation+++GO:0052472///modulation by host of symbiont transcription" 57247 57247 'Zfp276' mRNA 2101.25 2098.85 1988.08 27.71 27.79 27.98 16.01 14.09 15.23 27.82666667 15.11 1376.01 1227.75 1270.06 2062.726667 1291.273333 2.32E-21 -0.687964875 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0043035///chromatin insulator sequence binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 57248 57248 'Ly6i' mRNA 24 23 15 1.7 1.51 1.17 5.46 4.16 4.1 1.46 4.573333333 97 73 71 20.66666667 80.33333333 1.79E-07 1.950194964 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity 57249 57249 'Gabrq' mRNA 4 0 0 0.04 0 0 0 0.02 0 0.013333333 0.006666667 0 3 0 1.333333333 1 0.917128784 -0.380473325 04080///Neuroactive ligand-receptor interaction+++04723///Retrograde endocannabinoid signaling+++04727///GABAergic synapse+++05032///Morphine addiction+++05033///Nicotine addiction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:1902711///GABA-A receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0004890///GABA-A receptor activity+++GO:0005216///ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity+++GO:0030594///neurotransmitter receptor activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:1902476///chloride transmembrane transport 57253 57253 'Tas2r108' mRNA 5 2 2 0.37 0.15 0.16 0 0.13 0.13 0.226666667 0.086666667 0 2 2 3 1.333333333 0.589656049 -1.163256738 04742///Taste transduction GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0004930///G protein-coupled receptor activity+++GO:0008527///taste receptor activity+++GO:0033038///bitter taste receptor activity GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007585///respiratory gaseous exchange+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste 57257 57257 'Vav3' mRNA 456 515 445 7.93 8.88 8.3 4.02 3.46 3.48 8.37 3.653333333 283 246 259 472 262.6666667 1.57E-10 -0.85672244 04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05135///Yersinia infection+++05205///Proteoglycans in cancer+++05417///Lipid and atherosclerosis GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0006906///vesicle fusion+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007229///integrin-mediated signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0009410///response to xenobiotic stimulus+++GO:0016477///cell migration+++GO:0030031///cell projection assembly+++GO:0030032///lamellipodium assembly+++GO:0030593///neutrophil chemotaxis+++GO:0030890///positive regulation of B cell proliferation+++GO:0035556///intracellular signal transduction+++GO:0042493///response to drug+++GO:0043087///regulation of GTPase activity+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0050853///B cell receptor signaling pathway 57258 57258 'Xpo4' mRNA 593.94 586.92 398.88 3.55 3.44 2.48 2.07 2.01 2.43 3.156666667 2.17 393.47 394.73 459.06 526.58 415.7533333 0.028407269 -0.343399734 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005049///nuclear export signal receptor activity GO:0006611///protein export from nucleus+++GO:0015031///protein transport+++GO:0046827///positive regulation of protein export from nucleus+++GO:0051168///nuclear export+++GO:0051169///nuclear transport 57259 57259 'Tob2' mRNA 2004 2016 1559 26.38 26.22 21.95 24.97 19.91 21.8 24.85 22.22666667 2161 1701 1843 1859.666667 1901.666667 0.863090843 0.023395572 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003714///transcription corepressor activity+++GO:0042809///vitamin D receptor binding "GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045778///positive regulation of ossification+++GO:0045892///negative regulation of transcription, DNA-templated" 57260 57260 'Ltb4r2' mRNA 1 4 1 0.03 0.16 0.04 0.18 0.33 0.15 0.076666667 0.22 6 12 6 2 8 0.121998937 2.007939238 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001632///leukotriene B4 receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004974///leukotriene receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0051546///keratinocyte migration+++GO:0061737///leukotriene signaling pathway 57261 57261 'Brd4' mRNA 1803.38 1644.4 1534.04 13.63 12.42 11.32 15.78 15 16.09 12.45666667 15.62333333 2376.41 2143.01 2293.59 1660.606667 2271.003333 3.34E-09 0.440712397 GO:0000785///chromatin+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0008024///cyclin/CDK positive transcription elongation factor complex GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0019899///enzyme binding+++GO:0031493///nucleosomal histone binding+++GO:0034211///GTP-dependent protein kinase activity+++GO:0070577///lysine-acetylated histone binding+++GO:0099122///RNA polymerase II C-terminal domain binding+++GO:0106140///P-TEFb complex binding "GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0001833///inner cell mass cell proliferation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007059///chromosome segregation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043388///positive regulation of DNA binding+++GO:0043922///negative regulation by host of viral transcription+++GO:0043983///histone H4-K12 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0050727///regulation of inflammatory response+++GO:1901407///regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:2001255///positive regulation of histone H3-K36 trimethylation" 57262 57262 'Retnla' mRNA 1 1 2 0.15 0.15 0.32 1.44 2.03 1.23 0.206666667 1.566666667 11 15 9 1.333333333 11.66666667 0.008920631 3.112733949 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity GO:0007165///signal transduction 57264 57264 'Retn' mRNA 5 1 2 0.67 0.13 0.28 0.23 0.36 0.36 0.36 0.316666667 2 3 3 2.666666667 2.666666667 0.998591786 -0.005575338 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0010714///positive regulation of collagen metabolic process+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0032868///response to insulin+++GO:0045444///fat cell differentiation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050806///positive regulation of synaptic transmission+++GO:2000252///negative regulation of feeding behavior+++GO:2000872///positive regulation of progesterone secretion 57265 57265 'Fzd2' mRNA 356 360 288 5.33 5.3 4.57 6.77 7.04 7.22 5.066666667 7.01 521 529 538 334.6666667 529.3333333 2.56E-07 0.65368497 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0042813///Wnt-activated receptor activity+++GO:0046982///protein heterodimerization activity "GO:0003149///membranous septum morphogenesis+++GO:0003150///muscular septum morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0007608///sensory perception of smell+++GO:0016055///Wnt signaling pathway+++GO:0030855///epithelial cell differentiation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034260///negative regulation of GTPase activity+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060022///hard palate development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060119///inner ear receptor cell development+++GO:0060412///ventricular septum morphogenesis+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure" 57266 57266 'Cxcl14' mRNA 8367 8855 6545 254.59 266.41 212.02 38.36 37.31 37.3 244.34 37.65666667 1436 1364 1354 7922.333333 1384.666667 2.67E-236 -2.522462099 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus GO:0005125///cytokine activity+++GO:0008009///chemokine activity GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0031640///killing of cells of other organism+++GO:0045662///negative regulation of myoblast differentiation+++GO:0048839///inner ear development+++GO:0060326///cell chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:2000503///positive regulation of natural killer cell chemotaxis 57267 57267 'Apba3' mRNA 931 956 893 24.76 24.95 24.88 24.36 26.04 25.9 24.86333333 25.43333333 1066 1105 1086 926.6666667 1085.666667 0.018585994 0.217732136 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0048471///perinuclear region of cytoplasm GO:0001540///amyloid-beta binding+++GO:0004857///enzyme inhibitor activity+++GO:0019899///enzyme binding GO:0001701///in utero embryonic development+++GO:0007268///chemical synaptic transmission+++GO:0010468///regulation of gene expression+++GO:0015031///protein transport+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 57269 57269 'Olfr1507' mRNA 63 66.96 47 3.04 2.97 2.59 0.75 0.56 0.51 2.866666667 0.606666667 18 13 10 58.98666667 13.66666667 2.07E-06 -2.110017561 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 57270 57270 'Olfr1508' mRNA 8 4.04 9 0.25 0.12 0.29 0.05 0 0.08 0.22 0.043333333 2 0 3 7.013333333 1.666666667 0.140557629 -2.099336333 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005549///odorant binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 57271 57271 'Olfr1509' mRNA 1 1 1 0.06 0.06 0.07 0 0.34 0 0.063333333 0.113333333 0 6 0 1 2 0.738819666 1.010074902 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity+++GO:0005507///copper ion binding+++GO:0005549///odorant binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050907///detection of chemical stimulus involved in sensory perception+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 57274 57274 'Slc16a8' mRNA 30 21 29 0.51 0.35 0.53 0.08 0.12 0.2 0.463333333 0.133333333 5 8 13 26.66666667 8.666666667 0.011977314 -1.634585051 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0035873///lactate transmembrane transport+++GO:0055085///transmembrane transport 57275 57275 'Lenep' mRNA 91 101 89 9.92 10.94 10.3 5.06 4.22 4.85 10.38666667 4.71 53 43 49 93.66666667 48.33333333 0.001153464 -0.966309932 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0008150///biological_process 57276 57276 'Vsig2' mRNA 6 12 11 0.32 0.63 0.62 0.69 0.99 0.81 0.523333333 0.83 15 21 17 9.666666667 17.66666667 0.260332793 0.858306529 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 57277 57277 'Slurp1' mRNA 0 0 1 0 0 0.17 0 0.14 0.14 0.056666667 0.093333333 0 1 1 0.333333333 0.666666667 0.863090843 0.898087804 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0030549///acetylcholine receptor activator activity GO:0007626///locomotory behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0030336///negative regulation of cell migration+++GO:0038195///urokinase plasminogen activator signaling pathway+++GO:0050884///neuromuscular process controlling posture 57278 57278 'Bcam' mRNA 6302 6434 5532 146.36 147.12 136.29 152.55 137.72 148.86 143.2566667 146.3766667 7555 6660 7137 6089.333333 7117.333333 2.95E-04 0.214862979 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005055///laminin receptor activity+++GO:0008022///protein C-terminus binding+++GO:0043236///laminin binding GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion 57279 57279 'Slc25a20' mRNA 632 671 617 20.94 21.92 21.69 23.27 23.69 25.98 21.51666667 24.31333333 807 802 872 640 827 5.02E-04 0.359001168 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015227///acyl carnitine transmembrane transporter activity GO:0001701///in utero embryonic development+++GO:1902603///carnitine transmembrane transport+++GO:1902616///acyl carnitine transmembrane transport 57294 57294 'Rps27' mRNA 3851.78 3688.56 5114.09 1308.46 1272.73 1850.81 1039.57 1117.32 1241.28 1477.333333 1132.723333 3432.24 3564.45 3925.97 4218.143333 3640.886667 0.368936004 -0.233157285 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0000028///ribosomal small subunit assembly+++GO:0006364///rRNA processing+++GO:0006412///translation 57295 57295 'Icmt' mRNA 1299 1404 1399 14.06 14.95 16.07 11.05 9.91 10.25 15.02666667 10.40333333 1175 1030 1056 1367.333333 1087 1.71E-04 -0.345254507 00900///Terpenoid backbone biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004671///protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity+++GO:0008140///cAMP response element binding protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0001701///in utero embryonic development+++GO:0001889///liver development+++GO:0006479///protein methylation+++GO:0006481///C-terminal protein methylation+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0030282///bone mineralization+++GO:0031929///TOR signaling+++GO:0032259///methylation+++GO:0032880///regulation of protein localization+++GO:0035264///multicellular organism growth+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0046499///S-adenosylmethioninamine metabolic process+++GO:0046578///regulation of Ras protein signal transduction+++GO:0050905///neuromuscular process+++GO:1903827///regulation of cellular protein localization+++GO:2000772///regulation of cellular senescence 57296 57296 'Psmd8' mRNA 2364 2406 2263 92.21 92.56 93.64 156.63 156.83 159.06 92.80333333 157.5066667 4613 4507 4532 2344.333333 4550.666667 3.83E-61 0.945575821 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex" GO:0005515///protein binding GO:0006508///proteolysis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 57312 57312 'Mrps31' mRNA 455 402 398 17.48 15.27 16.19 14.35 13.52 15.66 16.31333333 14.51 429 394 453 418.3333333 425.3333333 0.944821911 0.012394489 GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding GO:0008150///biological_process 57314 57314 'Nelfcd' mRNA 1586 1568 1553 39.06 38.04 40.57 28.21 28.47 28.55 39.22333333 28.41 1316 1297 1290 1569 1301 3.93E-04 -0.282449662 GO:0005634///nucleus+++GO:0032021///NELF complex GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045892///negative regulation of transcription, DNA-templated" 57315 57315 'Wdr46' mRNA 496 534 541 12.93 13.69 14.98 16.18 16.51 17.91 13.86666667 16.86666667 713 711 764 523.6666667 729.3333333 4.22E-05 0.464969863 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 57316 57316 'C1d' mRNA 953 875 949 17.25 15.6 18.23 18.14 17.43 18.25 17.02666667 17.94 1152 1082 1122 925.6666667 1118.666667 0.008298334 0.259265431 03018///RNA degradation GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding "GO:0000460///maturation of 5.8S rRNA+++GO:0006364///rRNA processing+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated" 57317 57317 'Srsf4' mRNA 1792 1761 1807 42.15 40.73 45.66 33.73 35.06 33.39 42.84666667 34.06 1648 1648 1583 1786.666667 1626.333333 0.079395482 -0.148612709 03040///Spliceosome+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:1990825///sequence-specific mRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0032868///response to insulin+++GO:0048025///negative regulation of mRNA splicing, via spliceosome" 57319 57319 'Smpdl3a' mRNA 2902 3267 3028 93.45 103.68 103.44 83.21 79.34 79.82 100.19 80.79 2970 2764 2757 3065.666667 2830.333333 0.092047976 -0.12763895 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006685///sphingomyelin catabolic process+++GO:0008150///biological_process+++GO:0009143///nucleoside triphosphate catabolic process 57320 57320 'Park7' mRNA 3748 3762 3594 272.93 270.82 277.44 256.18 266.55 260.16 273.73 260.9633333 4036 4089 3958 3701.333333 4027.666667 0.089905929 0.110557449 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016605///PML body+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0061827///sperm head+++GO:0098793///presynapse "GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005102///signaling receptor binding+++GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008233///peptidase activity+++GO:0016532///superoxide dismutase copper chaperone activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0016787///hydrolase activity+++GO:0019826///oxygen sensor activity+++GO:0019899///enzyme binding+++GO:0019900///kinase binding+++GO:0019955///cytokine binding+++GO:0036470///tyrosine 3-monooxygenase activator activity+++GO:0036478///L-dopa decarboxylase activator activity+++GO:0036524///protein deglycase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0045340///mercury ion binding+++GO:0050681///androgen receptor binding+++GO:0051920///peroxiredoxin activity+++GO:0097110///scaffold protein binding+++GO:1903135///cupric ion binding+++GO:1903136///cuprous ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:1990422///glyoxalase (glycolic acid-forming) activity" "GO:0001933///negative regulation of protein phosphorylation+++GO:0001963///synaptic transmission, dopaminergic+++GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0006281///DNA repair+++GO:0006469///negative regulation of protein kinase activity+++GO:0006508///proteolysis+++GO:0006517///protein deglycosylation+++GO:0006914///autophagy+++GO:0006954///inflammatory response+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0007338///single fertilization+++GO:0008344///adult locomotory behavior+++GO:0009438///methylglyoxal metabolic process+++GO:0010273///detoxification of copper ion+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0016570///histone modification+++GO:0019249///lactate biosynthetic process+++GO:0030073///insulin secretion+++GO:0031334///positive regulation of protein complex assembly+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032757///positive regulation of interleukin-8 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033182///regulation of histone ubiquitination+++GO:0033234///negative regulation of protein sumoylation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0034599///cellular response to oxidative stress+++GO:0034614///cellular response to reactive oxygen species+++GO:0035065///regulation of histone acetylation+++GO:0036471///cellular response to glyoxal+++GO:0036526///peptidyl-cysteine deglycation+++GO:0036527///peptidyl-arginine deglycation+++GO:0036528///peptidyl-lysine deglycation+++GO:0036529///protein deglycation, glyoxal removal+++GO:0036530///protein deglycation, methylglyoxal removal+++GO:0036531///glutathione deglycation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042542///response to hydrogen peroxide+++GO:0042593///glucose homeostasis+++GO:0042743///hydrogen peroxide metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046295///glycolate biosynthetic process+++GO:0046826///negative regulation of protein export from nucleus+++GO:0050727///regulation of inflammatory response+++GO:0050787///detoxification of mercury ion+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051899///membrane depolarization+++GO:0060081///membrane hyperpolarization+++GO:0060548///negative regulation of cell death+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0061727///methylglyoxal catabolic process to lactate+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070994///detection of oxidative stress+++GO:0098869///cellular oxidant detoxification+++GO:0106044///guanine deglycation+++GO:0106045///guanine deglycation, methylglyoxal removal+++GO:0106046///guanine deglycation, glyoxal removal+++GO:0110095///cellular detoxification of aldehyde+++GO:0140041///cellular detoxification of methylglyoxal+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901215///negative regulation of neuron death+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1901984///negative regulation of protein acetylation+++GO:1902177///positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1902958///positive regulation of mitochondrial electron transport, NADH to ubiquinone+++GO:1903094///negative regulation of protein K48-linked deubiquitination+++GO:1903122///negative regulation of TRAIL-activated apoptotic signaling pathway+++GO:1903168///positive regulation of pyrroline-5-carboxylate reductase activity+++GO:1903178///positive regulation of tyrosine 3-monooxygenase activity+++GO:1903181///positive regulation of dopamine biosynthetic process+++GO:1903189///glyoxal metabolic process+++GO:1903190///glyoxal catabolic process+++GO:1903197///positive regulation of L-dopa biosynthetic process+++GO:1903200///positive regulation of L-dopa decarboxylase activity+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903384///negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:1904782///negative regulation of NMDA glutamate receptor activity+++GO:1905259///negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway+++GO:1905516///positive regulation of fertilization+++GO:2000157///negative regulation of ubiquitin-specific protease activity+++GO:2000277///positive regulation of oxidative phosphorylation uncoupler activity+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2000825///positive regulation of androgen receptor activity+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" 57321 57321 'Terf2ip' mRNA 1465.74 1426.48 1455.63 22.11 21.17 23.29 15.73 15.67 15.71 22.19 15.70333333 1199.67 1167.6 1160.97 1449.283333 1176.08 1.72E-04 -0.314556739 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0030870///Mre11 complex+++GO:0070187///shelterin complex" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0042162///telomeric DNA binding+++GO:0098505///G-rich strand telomeric DNA binding "GO:0000723///telomere maintenance+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0031627///telomeric loop formation+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0032204///regulation of telomere maintenance+++GO:0032205///negative regulation of telomere maintenance+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048239///negative regulation of DNA recombination at telomere+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070198///protein localization to chromosome, telomeric region+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901985///positive regulation of protein acetylation" 57329 57329 'Otor' mRNA 7006 7131 6831 432.3 435.05 447.24 547.91 564.51 544.25 438.1966667 552.2233333 10182 10226 9775 6989.333333 10061 2.15E-22 0.513867728 GO:0005576///extracellular region+++GO:0005794///Golgi apparatus GO:0001502///cartilage condensation 57330 57330 'Gigyf1' mRNA 1107 1055 917 10.52 9.87 9.24 6.67 6.26 6 9.876666667 6.31 810 736 698 1026.333333 748 1.92E-06 -0.466290124 GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0005515///protein binding GO:0048009///insulin-like growth factor receptor signaling pathway 57339 57339 'Jph1' mRNA 10 18 12 0.23 0.27 0.17 0.18 0.12 0.23 0.223333333 0.176666667 12 7 16 13.33333333 11.66666667 0.844504628 -0.202315002 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane GO:0008307///structural constituent of muscle GO:0007517///muscle organ development 57340 57340 'Jph3' mRNA 4 8 9 0.06 0.11 0.13 0.02 0.02 0.1 0.1 0.046666667 2 2 8 7 4 0.540313858 -0.824713193 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030314///junctional membrane complex GO:0007612///learning+++GO:0007613///memory+++GO:0035640///exploration behavior+++GO:0040011///locomotion+++GO:0048167///regulation of synaptic plasticity+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0050885///neuromuscular process controlling balance+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity 57342 57342 'Parva' mRNA 4075 4255 4303 50.9 52.02 56.91 42 39.57 39.35 53.27666667 40.30666667 3906 3611 3552 4211 3689.666667 0.003844986 -0.204776981 04510///Focal adhesion GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0003779///actin binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0006935///chemotaxis+++GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0008360///regulation of cell shape+++GO:0030030///cell projection organization+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0031532///actin cytoskeleton reorganization+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0043086///negative regulation of catalytic activity+++GO:0060271///cilium assembly+++GO:0070252///actin-mediated cell contraction+++GO:0071670///smooth muscle cell chemotaxis 57344 57344 'As3mt' mRNA 792 817 774 26.16 26.35 27.03 18.82 18.14 18.56 26.51333333 18.50666667 657 619 625 794.3333333 633.6666667 8.31E-04 -0.337922425 05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0030791///arsenite methyltransferase activity+++GO:0030792///methylarsonite methyltransferase activity GO:0009404///toxin metabolic process+++GO:0018872///arsonoacetate metabolic process+++GO:0032259///methylation+++GO:0046685///response to arsenic-containing substance 57349 57349 'Ppbp' mRNA 3 4 7 0.17 0.23 0.43 4.09 3.63 5.38 0.276666667 4.366666667 81 70 103 4.666666667 84.66666667 2.54E-15 4.16475069 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031091///platelet alpha granule GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0045236///CXCR chemokine receptor binding GO:0002523///leukocyte migration involved in inflammatory response+++GO:0006935///chemotaxis+++GO:0006952///defense response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0030593///neutrophil chemotaxis+++GO:0031640///killing of cells of other organism+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0070098///chemokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide 57354 57354 'Cramp1l' mRNA 1117.73 1109 423 7.86 7.67 3.18 3.43 3.16 3.28 6.236666667 3.29 558 503 519.05 883.2433333 526.6833333 0.103511795 -0.738022461 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003682///chromatin binding GO:0007389///pattern specification process 57355 57355 'BC051019' mRNA 0 4 1 0 0.13 0.04 0.06 0.03 0 0.056666667 0.03 2 1 0 1.666666667 1 0.817190466 -0.739127365 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 57357 57357 'Srd5a3' mRNA 730.56 752.78 627.46 18.34 19.43 16.4 32 28.94 30.32 18.05666667 30.42 1216.64 1081.16 1126.05 703.6 1141.283333 5.75E-14 0.688896614 00140///Steroid hormone biosynthesis+++00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003865///3-oxo-5-alpha-steroid 4-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0047751///cholestenone 5-alpha-reductase activity+++GO:0102389///polyprenol reductase activity" GO:0006486///protein glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0016095///polyprenol catabolic process+++GO:0019348///dolichol metabolic process+++GO:0019408///dolichol biosynthetic process 57370 57370 'B4galt3' mRNA 1346 1256 1217 38.36 35.26 36.79 36.27 36.26 34.11 36.80333333 35.54666667 1463 1428 1332 1273 1407.666667 0.143252236 0.133613665 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0003945///N-acetyllactosamine synthase activity+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006682///galactosylceramide biosynthetic process+++GO:0070085///glycosylation 57373 57373 'Akip1' mRNA 390 425 392 23.52 25.19 24.8 29.74 32.55 27.36 24.50333333 29.88333333 571 606 511 402.3333333 562.6666667 1.99E-04 0.472952772 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0034446///substrate adhesion-dependent cell spreading+++GO:1901222///regulation of NIK/NF-kappaB signaling 57376 57376 'Smarce1' mRNA 1043 1039 836 19.67 19.28 16.72 22.68 21.83 22.61 18.55666667 22.37333333 1384 1301 1336 972.6666667 1340.333333 3.15E-07 0.454351056 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0016922///nuclear receptor binding+++GO:0047485///protein N-terminus binding "GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045892///negative regulation of transcription, DNA-templated" 57377 57377 'Mogs' mRNA 136 147 136 2.71 3.04 3.12 4.35 2.99 4.56 2.956666667 3.966666667 234 157 243 139.6666667 211.3333333 0.007913809 0.583732462 00510///N-Glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004573///mannosyl-oligosaccharide glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0006487///protein N-linked glycosylation+++GO:0008152///metabolic process+++GO:0009311///oligosaccharide metabolic process 57385 57385 'P2ry4' mRNA 5.89 3.29 3 0.05 0.04 0.03 0.01 0.02 0.03 0.04 0.02 1 2 4.42 4.06 2.473333333 0.727973519 -0.655401674 04080///Neuroactive ligand-receptor interaction+++04742///Taste transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0004930///G protein-coupled receptor activity+++GO:0005524///ATP binding+++GO:0019103///pyrimidine nucleotide binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045030///UTP-activated nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030321///transepithelial chloride transport+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:2000300///regulation of synaptic vesicle exocytosis 57390 57390 'Psors1c2' mRNA 12 14 9 0.71 0.53 0.42 0.04 0.14 0.43 0.553333333 0.203333333 2 4 9 11.66666667 5 0.222634964 -1.222052624 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 57394 57394 'Cltrn' mRNA 51 33 46 2.51 1.74 2.49 0.55 0.53 0.96 2.246666667 0.68 13 11 22 43.33333333 15.33333333 0.002678521 -1.514380608 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane GO:0005515///protein binding+++GO:0042803///protein homodimerization activity GO:0017156///calcium ion regulated exocytosis+++GO:0022898///regulation of transmembrane transporter activity+++GO:0035493///SNARE complex assembly+++GO:0035543///positive regulation of SNARE complex assembly+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0051957///positive regulation of amino acid transport+++GO:1905737///positive regulation of L-proline import across plasma membrane 57423 57423 'Atp5j2' mRNA 2047 1995 2343 454.66 445.64 552.88 438.06 515.67 489.99 484.3933333 481.24 2233 2545 2398 2128.333333 2392 0.165650435 0.153291797 00190///Oxidative phosphorylation+++04714///Thermogenesis "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process 57426 57426 'Scgb1b2' mRNA 1 0 1 0.23 0 0.25 0 0 0 0.16 0 0 0 0 0.666666667 0 0.746936975 -1.892661915 GO:0005576///extracellular region GO:0005496///steroid binding GO:0008150///biological_process 57429 57429 'Sult5a1' mRNA 285 288 269 14.92 15.11 15.33 30.96 29.85 28.96 15.12 29.92333333 684 637 612 280.6666667 644.3333333 1.93E-23 1.187347867 GO:0005737///cytoplasm GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0051923///sulfation 57431 57431 'Dnajc4' mRNA 435 413 406 31 29.73 30.06 24.76 24.8 22.49 30.26333333 24.01666667 418 414 364 418 398.6666667 0.634852323 -0.080164027 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane 57432 57432 'Zc3h8' mRNA 190 151 150 7.1 5.55 5.92 3.43 3.29 3.51 6.19 3.41 106 99 105 163.6666667 103.3333333 0.002708738 -0.674212466 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0035327///transcriptionally active chromatin+++GO:0035363///histone locus body "GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III+++GO:0043029///T cell homeostasis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0046677///response to antibiotic+++GO:0070245///positive regulation of thymocyte apoptotic process" 57434 57434 'Xrcc2' mRNA 305.69 280.19 293.04 5.19 4.69 5.28 3.03 3.34 3.4 5.053333333 3.256666667 205 221 222.69 292.9733333 216.23 0.006785952 -0.450183926 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005813///centrosome+++GO:0033063///Rad51B-Rad51C-Rad51D-XRCC2 complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity GO:0000278///mitotic cell cycle+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001701///in utero embryonic development+++GO:0001756///somitogenesis+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007098///centrosome cycle+++GO:0010165///response to X-ray+++GO:0010332///response to gamma radiation+++GO:0022008///neurogenesis+++GO:0035264///multicellular organism growth+++GO:0042148///strand invasion+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050769///positive regulation of neurogenesis+++GO:2000269///regulation of fibroblast apoptotic process 57435 57435 'Plin4' mRNA 451 441 429 3.78 3.6 3.86 2.48 1.9 2.2 3.746666667 2.193333333 341 260 287 440.3333333 296 3.62E-05 -0.586767906 03320///PPAR signaling pathway GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane 57436 57436 'Gabarapl1' mRNA 6474 6679 6023 210.85 214.4 208.1 161.78 158.64 166.71 211.1166667 162.3766667 5709 5464 5693 6392 5622 2.40E-04 -0.195806392 04068///FoxO signaling pathway+++04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04212///Longevity regulating pathway - worm+++04621///NOD-like receptor signaling pathway+++04727///GABAergic synapse GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032590///dendrite membrane+++GO:0032839///dendrite cytoplasm+++GO:0044297///cell body GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0030957///Tat protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0050811///GABA receptor binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0006995///cellular response to nitrogen starvation+++GO:0016236///macroautophagy 57437 57437 'Golga7' mRNA 2409 2528 2487 74.63 76.14 81.82 80.97 84.31 82.57 77.53 82.61666667 3023 3065 2970.87 2474.666667 3019.623333 8.88E-05 0.274603618 GO:0000139///Golgi membrane+++GO:0002178///palmitoyltransferase complex+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0031228///intrinsic component of Golgi membrane GO:0006612///protein targeting to membrane+++GO:0006893///Golgi to plasma membrane transport+++GO:0018215///protein phosphopantetheinylation+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0050821///protein stabilization 57438 57438 'Marchf7' mRNA 1265 1231 1288 20.88 19.89 22.24 18.08 18.02 17.94 21.00333333 18.01333333 1355 1273 1281 1261.333333 1303 0.778803744 0.033120211 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0097371///MDM2/MDM4 family protein binding "GO:0002643///regulation of tolerance induction+++GO:0006513///protein monoubiquitination+++GO:0008284///positive regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0042130///negative regulation of T cell proliferation+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0050821///protein stabilization+++GO:0051865///protein autoubiquitination+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1902916///positive regulation of protein polyubiquitination+++GO:1905524///negative regulation of protein autoubiquitination" 57439 57439 'Tmem183a' mRNA 2344 2534 2479 40.48 43.06 45.42 24.16 23.5 23.52 42.98666667 23.72666667 1610 1529 1517 2452.333333 1552 1.06E-19 -0.673193189 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019005///SCF ubiquitin ligase complex GO:0003674///molecular_function GO:0031647///regulation of protein stability 57440 57440 'Ehd3' mRNA 7312 8020 7888 108.43 116.99 124.07 68.12 65.5 65.99 116.4966667 66.53666667 5287 4966 4960 7740 5071 1.19E-22 -0.623788828 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0005929///cilium+++GO:0010008///endosome membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0020018///ciliary pocket membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0060170///ciliary membrane GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001881///receptor recycling+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0030030///cell projection organization+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0032456///endocytic recycling+++GO:0034498///early endosome to Golgi transport+++GO:0051260///protein homooligomerization+++GO:0055117///regulation of cardiac muscle contraction+++GO:0060271///cilium assembly+++GO:0072659///protein localization to plasma membrane+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090160///Golgi to lysosome transport+++GO:0097320///plasma membrane tubulation+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1901741///positive regulation of myoblast fusion+++GO:1903358///regulation of Golgi organization+++GO:1903779///regulation of cardiac conduction+++GO:2001137///positive regulation of endocytic recycling 574402 574402 'Gpr17' mRNA 2 4 9 0.02 0.04 0.1 0.08 0.04 0.18 0.053333333 0.1 9 4 19 5 10.66666667 0.353363458 1.057734316 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0033612///receptor serine/threonine kinase binding GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0048709///oligodendrocyte differentiation+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 574403 574403 'Insyn2b' mRNA 7 10 8 0.07 0.1 0.08 0.85 0.7 0.7 0.083333333 0.75 99 79 79 8.333333333 85.66666667 1.91E-14 3.349293045 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 574404 574404 'Gm14685' mRNA 35.89 50.61 41.66 0.67 0.9 0.86 0.1 0.3 0.14 0.81 0.18 5.96 17.1 8.42 42.72 10.49333333 2.19E-04 -2.074297749 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 574405 574405 'DXBay18' mRNA 12.08 38.34 36.19 0.23 0.72 0.74 0.25 0.22 0.14 0.563333333 0.203333333 15.04 12.79 8.58 28.87 12.13666667 0.04642231 -1.318168187 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 57441 57441 'Gmnn' mRNA 200.08 181.95 171 4.52 4.05 4.32 19.11 17.97 16.83 4.296666667 17.97 427.98 421.95 390.23 184.3433333 413.3866667 3.90E-15 1.154661207 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0072686///mitotic spindle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0003924///GTPase activity+++GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0042826///histone deacetylase binding+++GO:0070491///repressing transcription factor binding "GO:0000278///mitotic cell cycle+++GO:0006275///regulation of DNA replication+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0009887///animal organ morphogenesis+++GO:0035563///positive regulation of chromatin binding+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051276///chromosome organization+++GO:0051310///metaphase plate congression+++GO:0065003///protein-containing complex assembly+++GO:0071163///DNA replication preinitiation complex assembly+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:2000104///negative regulation of DNA-dependent DNA replication" 574418 574418 'Serinc4' mRNA 15.28 16.21 19.08 0.35 0.47 0.49 0.24 0.44 0.22 0.436666667 0.3 12.42 16.77 10.93 16.85666667 13.37333333 0.610834743 -0.410633349 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process 57442 57442 'Kcne3' mRNA 14 19 15 0.42 0.71 0.56 0.73 1.04 0.38 0.563333333 0.716666667 18 22 6 16 15.33333333 0.937264812 -0.070530523 04974///Protein digestion and absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0031982///vesicle+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:1990794///basolateral part of cell GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0030644///cellular chloride ion homeostasis+++GO:0034765///regulation of ion transmembrane transport+++GO:0043266///regulation of potassium ion transport+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071805///potassium ion transmembrane transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1905025///negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential 574428 574428 'Zmynd15' mRNA 61.24 77.78 73.4 1.46 1.46 1.87 4.46 6.06 4.56 1.596666667 5.026666667 228.66 285.76 238.28 70.80666667 250.9 2.30E-17 1.821107976 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding "GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 574429 574429 'Psg26' mRNA 3 0 1 0.08 0 0.04 0 0 0 0.04 0 0 0 0 1.333333333 0 0.48037534 -2.868446001 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0008150///biological_process 57443 57443 'Fbxo3' mRNA 2618.98 2749.93 2647.95 54.93 57.01 59.2 51.04 50.05 51.02 57.04666667 50.70333333 2825.95 2616.96 2723.98 2672.286667 2722.296667 0.869446286 0.014107111 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol 574437 574437 'Xlr3b' mRNA 304.76 331.3 333.72 10.9 11.72 12.73 4.63 4.57 4.34 11.78333333 4.513333333 148.32 142.92 134.73 323.26 141.99 5.74E-13 -1.20459644 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis 574438 574438 'Xlr5a' mRNA 0 0 1.81 0 0 0.11 0 0 0 0.036666667 0 0 0 0 0.603333333 0 0.863090843 -0.97353728 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 57444 57444 'Isg20' mRNA 32 37 28 2.31 2.22 1.76 12.93 12.89 10.9 2.096666667 12.24 240 228 190 32.33333333 219.3333333 5.30E-28 2.752383289 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016605///PML body GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0008859///exoribonuclease II activity+++GO:0016787///hydrolase activity+++GO:0030619///U1 snRNA binding+++GO:0030620///U2 snRNA binding+++GO:0034511///U3 snoRNA binding+++GO:0046872///metal ion binding "GO:0000738///DNA catabolic process, exonucleolytic+++GO:0002376///immune system process+++GO:0006364///rRNA processing+++GO:0006401///RNA catabolic process+++GO:0009615///response to virus+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 57738 57738 'Slc15a2' mRNA 835 811 816 27.74 26.6 27.21 14.11 13.14 13.22 27.18333333 13.49 484 457 449 820.6666667 463.3333333 9.06E-16 -0.837559494 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0015293///symporter activity+++GO:0015333///peptide:proton symporter activity+++GO:0015334///high-affinity oligopeptide transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0035673///oligopeptide transmembrane transporter activity+++GO:0071916///dipeptide transmembrane transporter activity GO:0002376///immune system process+++GO:0006857///oligopeptide transport+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0015835///peptidoglycan transport+++GO:0042908///xenobiotic transport+++GO:0042938///dipeptide transport+++GO:0045087///innate immune response+++GO:0055085///transmembrane transport+++GO:0070293///renal absorption+++GO:0070424///regulation of nucleotide-binding oligomerization domain containing signaling pathway+++GO:0140206///dipeptide import across plasma membrane+++GO:1902600///proton transmembrane transport 57740 57740 'Stk32c' mRNA 13 18 4 0.4 0.48 0.13 0 0 0 0.336666667 0 0 0 0 11.66666667 0 2.51E-04 -5.974364018 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 57741 57741 'Noc2l' mRNA 155.46 182.76 164.79 3.06 3.57 3.43 4.19 3.74 4.24 3.353333333 4.056666667 248.72 213.64 239.19 167.67 233.85 0.011572142 0.470232142 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0030690///Noc1p-Noc2p complex+++GO:0030691///Noc2p-Noc3p complex GO:0002039///p53 binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0031491///nucleosome binding+++GO:0031493///nucleosomal histone binding+++GO:0042393///histone binding+++GO:0070491///repressing transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002903///negative regulation of B cell apoptotic process+++GO:0006915///apoptotic process+++GO:0031497///chromatin assembly+++GO:0034644///cellular response to UV+++GO:0035067///negative regulation of histone acetylation+++GO:0042273///ribosomal large subunit biogenesis+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 57743 57743 'Sec61a2' mRNA 1388.58 1464.03 1423.68 23.12 24.21 25.54 15.05 16.07 14.6 24.29 15.24 1052.64 1002 975.79 1425.43 1010.143333 1.10E-09 -0.509795799 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05110///Vibrio cholerae infection GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005048///signal sequence binding+++GO:0008320///protein transmembrane transporter activity+++GO:0043022///ribosome binding "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0015031///protein transport+++GO:0031204///posttranslational protein targeting to membrane, translocation" 57745 57745 'Zfp112' mRNA 72 64 73 1.08 1.03 1.21 1.06 0.66 0.92 1.106666667 0.88 75 47 68 69.66666667 63.33333333 0.715420073 -0.154793794 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 57746 57746 'Piwil2' mRNA 9 14 13 0.08 0.13 0.14 0.41 0.16 0.22 0.116666667 0.263333333 45 17 23 12 28.33333333 0.056782898 1.21719473 04320///Dorso-ventral axis formation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010370///perinucleolar chromocenter+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0071546///pi-body+++GO:0097433///dense body+++GO:1990923///PET complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0034584///piRNA binding+++GO:0046872///metal ion binding+++GO:1905538///polysome binding "GO:0000239///pachytene+++GO:0000966///RNA 5'-end processing+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0030718///germ-line stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0042754///negative regulation of circadian rhythm+++GO:0043046///DNA methylation involved in gamete generation+++GO:0045727///positive regulation of translation+++GO:0048477///oogenesis+++GO:0048511///rhythmic process+++GO:0051321///meiotic cell cycle+++GO:0060903///positive regulation of meiosis I+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1990511///piRNA biosynthetic process+++GO:2000617///positive regulation of histone H3-K9 acetylation" 57748 57748 'Jmy' mRNA 905 848 800 5.41 4.98 5.07 3.21 3.07 3.03 5.153333333 3.103333333 619 578 566 851 587.6666667 5.10E-08 -0.545369565 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0031252///cell leading edge GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0071933///Arp2/3 complex binding "GO:0006281///DNA repair+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007050///cell cycle arrest+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0043065///positive regulation of apoptotic process+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051726///regulation of cell cycle+++GO:0070060///'de novo' actin filament nucleation+++GO:0070358///actin polymerization-dependent cell motility+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator" 57749 57749 'Piwil1' mRNA 30 34 29 0.42 0.47 0.43 0.12 0.09 0.14 0.44 0.116666667 10 7 11 31 9.333333333 0.002610253 -1.743194323 04320///Dorso-ventral axis formation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0097433///dense body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0034584///piRNA binding+++GO:0046872///metal ion binding+++GO:0140262///mRNA cap binding complex binding+++GO:1905538///polysome binding "GO:0000239///pachytene+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 57750 57750 'Wdr12' mRNA 944.08 950.79 916.71 14.46 14.48 14.66 10.48 10.45 10.31 14.53333333 10.41333333 806.94 807.18 776.83 937.1933333 796.9833333 0.011003493 -0.245814796 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex" GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0007219///Notch signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0051726///regulation of cell cycle" 57751 57751 'Rnf25' mRNA 382 370 339 15.3 14.74 14.49 15.15 16.66 16.66 14.84333333 16.15666667 434 459 462 363.6666667 451.6666667 0.024409298 0.302946217 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 57752 57752 'Tacc2' mRNA 2008.63 2104.5 1734.37 19.86 21.31 18.37 8.27 7.68 9.14 19.84666667 8.363333333 991.88 892.49 1058.39 1949.166667 980.92 5.48E-32 -1.000070015 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane GO:0016922///nuclear receptor binding+++GO:0019904///protein domain specific binding+++GO:0035257///nuclear hormone receptor binding GO:0000226///microtubule cytoskeleton organization+++GO:0007052///mitotic spindle organization+++GO:0008283///cell proliferation+++GO:0021987///cerebral cortex development+++GO:0022008///neurogenesis+++GO:0022027///interkinetic nuclear migration+++GO:0030953///astral microtubule organization+++GO:0032886///regulation of microtubule-based process 57753 57753 'Noc3l' mRNA 101 114 91 1.37 1.52 1.31 2.1 1.67 1.67 1.4 1.813333333 178 138 137 102 151 0.01943877 0.554930156 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0016607///nuclear speck GO:0003682///chromatin binding GO:0006270///DNA replication initiation+++GO:0045444///fat cell differentiation 57754 57754 'Cend1' mRNA 48 66 43 1.52 2.06 1.42 1.55 2.64 1.45 1.666666667 1.88 56 93 51 52.33333333 66.66666667 0.415543775 0.347511901 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle GO:0005515///protein binding GO:0007628///adult walking behavior+++GO:0021549///cerebellum development+++GO:0021686///cerebellar granular layer maturation+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021933///radial glia guided migration of cerebellar granule cell+++GO:0021941///negative regulation of cerebellar granule cell precursor proliferation+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation 57755 57755 'Dnajb7' mRNA 37 28 24 1.92 1.44 1.32 0.9 0.83 0.47 1.56 0.733333333 20 18 10 29.66666667 16 0.120563213 -0.89961505 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0008150///biological_process+++GO:0061077///chaperone-mediated protein folding 57756 57756 'Fhl5' mRNA 2 1 1 0.12 0.06 0.06 0.1 0.16 0.27 0.08 0.176666667 2 3 5 1.333333333 3.333333333 0.49484972 1.318394226 GO:0005634///nucleus+++GO:0030018///Z disc GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 57757 57757 'Pglyrp2' mRNA 3 5 1 0.07 0.15 0.04 0.2 0.24 0.49 0.086666667 0.31 10 11 17 3 12.66666667 0.039689885 2.083891778 04624///Toll and Imd signaling pathway GO:0005576///extracellular region+++GO:0016020///membrane GO:0008270///zinc ion binding+++GO:0008745///N-acetylmuramoyl-L-alanine amidase activity+++GO:0016019///peptidoglycan receptor activity+++GO:0016787///hydrolase activity+++GO:0042834///peptidoglycan binding+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0009253///peptidoglycan catabolic process+++GO:0016045///detection of bacterium+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032827///negative regulation of natural killer cell differentiation involved in immune response+++GO:0050727///regulation of inflammatory response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051701///interaction with host 57764 57764 'Ntn4' mRNA 46 45 23 1.07 1.03 0.57 0.42 0.37 0.6 0.89 0.463333333 21 18 29 38 22.66666667 0.154131657 -0.745026806 04360///Axon guidance GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0043256///laminin complex GO:0005515///protein binding+++GO:0043237///laminin-1 binding GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0016322///neuron remodeling+++GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0060668///regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling+++GO:0070831///basement membrane assembly 57765 57765 'Tbx21' mRNA 8 0 1 0.17 0 0.02 0.4 0.21 0.29 0.063333333 0.3 21 11 15 3 15.66666667 0.024606604 2.377056618 04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05321///Inflammatory bowel disease GO:0005634///nucleus+++GO:0043025///neuronal cell body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0001947///heart looping+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009615///response to virus+++GO:0010628///positive regulation of gene expression+++GO:0030217///T cell differentiation+++GO:0032703///negative regulation of interleukin-2 production+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045580///regulation of T cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0050776///regulation of immune response+++GO:0071310///cellular response to organic substance+++GO:0072676///lymphocyte migration+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:2000329///negative regulation of T-helper 17 cell lineage commitment+++GO:2000552///negative regulation of T-helper 2 cell cytokine production" 57773 57773 'Wdr4' mRNA 424.87 545.01 504.99 5.47 6.88 6.96 6.45 6.31 6.26 6.436666667 6.34 566 530.19 517 491.6233333 537.73 0.452681623 0.11781237 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0043527///tRNA methyltransferase complex GO:0008176///tRNA (guanine-N7-)-methyltransferase activity GO:0006400///tRNA modification+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0036265///RNA (guanine-N7)-methylation+++GO:0106004///tRNA (guanine-N7)-methylation 57775 57775 'Usp29' mRNA 56 51 51 0.39 0.35 0.38 0.06 0.04 0.03 0.373333333 0.043333333 10 7 4 52.66666667 7 2.42E-08 -2.925767349 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 57776 57776 'Ttyh1' mRNA 1555.81 1717.01 976.88 27.52 29.98 18.6 7.77 8.49 9.12 25.36666667 8.46 499.9 539 577.02 1416.566667 538.64 1.01E-22 -1.394473307 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030868///smooth endoplasmic reticulum membrane+++GO:0031527///filopodium membrane+++GO:0032433///filopodium tip+++GO:0034707///chloride channel complex+++GO:0045202///synapse GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0005509///calcium ion binding+++GO:0072320///volume-sensitive chloride channel activity GO:0000278///mitotic cell cycle+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007155///cell adhesion+++GO:0031589///cell-substrate adhesion+++GO:0046847///filopodium assembly+++GO:0098609///cell-cell adhesion 57778 57778 'Fmnl1' mRNA 59 58 37 0.82 0.81 0.55 5.55 5.45 5.69 0.726666667 5.563333333 455 435 451 51.33333333 447 4.41E-61 3.11529253 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0003779///actin binding+++GO:0005522///profilin binding+++GO:0031267///small GTPase binding+++GO:0032794///GTPase activating protein binding+++GO:0051015///actin filament binding GO:0006929///substrate-dependent cell migration+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0009987///cellular process+++GO:0016043///cellular component organization+++GO:0016477///cell migration+++GO:0022604///regulation of cell morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization+++GO:0051014///actin filament severing 57780 57780 'Fxyd7' mRNA 38 15 21 4.06 1.59 2.38 2.9 3.27 3.58 2.676666667 3.25 31 34 37 24.66666667 34 0.436801084 0.453787222 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017080///sodium channel regulator activity+++GO:0051117///ATPase binding+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0043269///regulation of ion transport+++GO:2000649///regulation of sodium ion transmembrane transporter activity 57781 57781 'Cd200r1' mRNA 9 7 4 0.27 0.21 0.13 8.9 8.88 8.02 0.203333333 8.6 337.66 329.03 294.54 6.666666667 320.41 1.36E-50 5.575610061 05167///Kaposi sarcoma-associated herpesvirus infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion GO:0032715///negative regulation of interleukin-6 production+++GO:0034113///heterotypic cell-cell adhesion+++GO:0150077///regulation of neuroinflammatory response+++GO:0150079///negative regulation of neuroinflammatory response+++GO:1901215///negative regulation of neuron death+++GO:1905522///negative regulation of macrophage migration+++GO:2000405///negative regulation of T cell migration 57782 57782 'Rbak' mRNA 316.84 325.81 332.01 5.1 5.15 5.67 3.74 3.89 3.72 5.306666667 3.783333333 269.87 272.59 257.73 324.8866667 266.73 0.060295094 -0.299021125 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 57783 57783 'Tnip1' mRNA 956 1040 733 19.13 20.44 15.48 20.83 21.62 19.34 18.35 20.59666667 1195 1220 1087 909.6666667 1167.333333 0.001394663 0.354483141 05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006954///inflammatory response+++GO:0007159///leukocyte cell-cell adhesion+++GO:0009101///glycoprotein biosynthetic process+++GO:0042254///ribosome biogenesis+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043489///RNA stabilization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051973///positive regulation of telomerase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0085032///modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade+++GO:0090669///telomerase RNA stabilization+++GO:1903003///positive regulation of protein deubiquitination+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1905323///telomerase holoenzyme complex assembly 57784 57784 'Bin3' mRNA 622 563 576 22.4 20.13 21.94 38.4 35.31 34.04 21.49 35.91666667 1181 1064 1003 587 1082.666667 4.55E-18 0.870072845 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton GO:0008289///lipid binding GO:0000917///division septum assembly+++GO:0006897///endocytosis+++GO:0007049///cell cycle+++GO:0008104///protein localization+++GO:0009826///unidimensional cell growth+++GO:0010591///regulation of lamellipodium assembly+++GO:0014839///myoblast migration involved in skeletal muscle regeneration+++GO:0043403///skeletal muscle tissue regeneration+++GO:0048741///skeletal muscle fiber development+++GO:0051301///cell division+++GO:0051666///actin cortical patch localization+++GO:0097320///plasma membrane tubulation 57785 57785 'Rangrf' mRNA 237.26 254.74 218.22 19.2 20.46 18.79 18.9 16.87 21.55 19.48333333 19.10666667 267.46 232.55 294.57 236.74 264.86 0.445562169 0.151195486 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017080///sodium channel regulator activity+++GO:0031267///small GTPase binding+++GO:0044325///ion channel binding GO:0003254///regulation of membrane depolarization+++GO:0006606///protein import into nucleus+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0042391///regulation of membrane potential+++GO:0050790///regulation of catalytic activity+++GO:0060047///heart contraction+++GO:0090226///regulation of microtubule nucleation by Ran protein signal transduction+++GO:0098905///regulation of bundle of His cell action potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:1900825///regulation of membrane depolarization during cardiac muscle cell action potential+++GO:1902305///regulation of sodium ion transmembrane transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:2000010///positive regulation of protein localization to cell surface+++GO:2000649///regulation of sodium ion transmembrane transporter activity 57808 57808 'Rpl35a' mRNA 1207.96 1145.06 1401.49 209.64 198.66 258.71 287.42 315.3 332.03 222.3366667 311.5833333 1887.32 2018.69 2100.52 1251.503333 2002.176667 2.59E-10 0.661905162 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0043021///ribonucleoprotein complex binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002181///cytoplasmic translation+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0071493///cellular response to UV-B" 57810 57810 'Cdon' mRNA 1606 1568 1369 9.15 8.41 8.04 6.29 5.75 6.27 8.533333333 6.103333333 1408 1237 1338 1514.333333 1327.666667 0.019037205 -0.200014803 04340///Hedgehog signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0001708///cell fate specification+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002088///lens development in camera-type eye+++GO:0007155///cell adhesion+++GO:0007224///smoothened signaling pathway+++GO:0007399///nervous system development+++GO:0007520///myoblast fusion+++GO:0009952///anterior/posterior pattern specification+++GO:0010172///embryonic body morphogenesis+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0016202///regulation of striated muscle tissue development+++GO:0021987///cerebral cortex development+++GO:0043393///regulation of protein binding+++GO:0043410///positive regulation of MAPK cascade+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048598///embryonic morphogenesis+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051146///striated muscle cell differentiation+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0098609///cell-cell adhesion+++GO:2000179///positive regulation of neural precursor cell proliferation 57811 57811 'Rgr' mRNA 13 14 9 0.53 0.46 0.25 0.03 0 0.09 0.413333333 0.04 1 0 3 12 1.333333333 0.008926218 -3.174667848 GO:0001750///photoreceptor outer segment+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0009584///detection of visible light+++GO:0018298///protein-chromophore linkage+++GO:0050896///response to stimulus+++GO:0071482///cellular response to light stimulus 57813 57813 'Tk2' mRNA 2133 2195 2236 49.8 50.59 55.69 33.75 31.22 33.55 52.02666667 32.84 1645 1490 1594 2188 1576.333333 3.13E-10 -0.487043695 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane GO:0000166///nucleotide binding+++GO:0004137///deoxycytidine kinase activity+++GO:0004797///thymidine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019136///deoxynucleoside kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006264///mitochondrial DNA replication+++GO:0009157///deoxyribonucleoside monophosphate biosynthetic process+++GO:0009262///deoxyribonucleotide metabolic process+++GO:0016310///phosphorylation+++GO:0032042///mitochondrial DNA metabolic process+++GO:0046092///deoxycytidine metabolic process+++GO:0046104///thymidine metabolic process+++GO:0071897///DNA biosynthetic process 57814 57814 'Kcne4' mRNA 31 48 49 0.69 1.05 1.15 0.79 0.59 0.56 0.963333333 0.646666667 41 30 28 42.66666667 33 0.433478825 -0.389493693 GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0071805///potassium ion transmembrane transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1902260///negative regulation of delayed rectifier potassium channel activity 57815 57815 'Spata5' mRNA 309.76 280 377.28 5.64 4.88 7.28 5.47 5.61 5.01 5.933333333 5.363333333 351.25 352.75 309.89 322.3466667 337.9633333 0.844451591 0.04844768 03008///Ribosome biogenesis in eukaryotes GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0030154///cell differentiation 57816 57816 'Tesc' mRNA 631 691 279 38.84 42.05 18.22 11.22 20.65 21.66 33.03666667 17.84333333 209 375 390 533.6666667 324.6666667 0.187614896 -0.703944551 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0000287///magnesium ion binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005509///calcium ion binding+++GO:0019212///phosphatase inhibitor activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0006883///cellular sodium ion homeostasis+++GO:0008285///negative regulation of cell proliferation+++GO:0008584///male gonad development+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0035855///megakaryocyte development+++GO:0043086///negative regulation of catalytic activity+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050821///protein stabilization+++GO:0051604///protein maturation+++GO:0071300///cellular response to retinoic acid+++GO:0072659///protein localization to plasma membrane" 57837 57837 'Eral1' mRNA 658 661 718 18.59 18.39 21.52 16.12 15.96 12.49 19.5 14.85666667 656 634 492 679 594 0.150655135 -0.208289494 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0019843///rRNA binding+++GO:0043024///ribosomal small subunit binding GO:0000028///ribosomal small subunit assembly+++GO:0042254///ribosome biogenesis 57869 57869 'Adck2' mRNA 750 761 791 14.17 13.32 14.78 8.11 8.32 8.87 14.09 8.433333333 546 563 592 767.3333333 567 5.16E-05 -0.449523961 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0008150///biological_process+++GO:0016310///phosphorylation 57874 57874 'Hacd3' mRNA 4491 4772 4551 90.89 95.06 97.7 75.61 75.87 75.38 94.55 75.62 4298 4212 4149 4604.666667 4219.666667 0.030717722 -0.138097748 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0019899///enzyme binding+++GO:0102158///very-long-chain 3-hydroxyacyl-CoA dehydratase activity+++GO:0102343///3-hydroxy-arachidoyl-CoA dehydratase activity+++GO:0102344///3-hydroxy-behenoyl-CoA dehydratase activity+++GO:0102345///3-hydroxy-lignoceroyl-CoA dehydratase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007254///JNK cascade+++GO:0007266///Rho protein signal transduction+++GO:0030148///sphingolipid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0045070///positive regulation of viral genome replication+++GO:0046726///positive regulation by virus of viral protein levels in host cell 57875 57875 'Angptl4' mRNA 158 151 115 4.75 4.48 3.67 15.34 15.58 14.93 4.3 15.28333333 586 581 552 141.3333333 573 3.06E-44 2.011809244 03320///PPAR signaling pathway+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0004857///enzyme inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0001666///response to hypoxia+++GO:0006629///lipid metabolic process+++GO:0009267///cellular response to starvation+++GO:0043066///negative regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043335///protein unfolding+++GO:0045834///positive regulation of lipid metabolic process+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0070328///triglyceride homeostasis+++GO:2000352///negative regulation of endothelial cell apoptotic process 57890 57890 'Il17re' mRNA 2080 2267 2248 43.22 46.48 49.35 35.45 36.89 34.71 46.35 35.68333333 1963 1989 1845 2198.333333 1932.333333 0.017724038 -0.199132557 04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030368///interleukin-17 receptor activity GO:0006954///inflammatory response+++GO:0019221///cytokine-mediated signaling pathway 57895 57895 'Ccdc126' mRNA 298 308 254 7.07 7.2 6.39 5.33 5.69 5.77 6.886666667 5.596666667 259 269 270 286.6666667 266 0.538335554 -0.116205793 GO:0005576///extracellular region 57896 57896 'Krcc1' mRNA 1274 1191 1129 21.82 20.08 20.51 19.37 21.48 21.02 20.80333333 20.62333333 1301 1409 1367 1198 1359 0.063758705 0.172015879 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 57905 57905 'Isy1' mRNA 397 489 392 14.3 17.37 15 22.54 22.24 25.79 15.55666667 23.52333333 721 693 797 426 737 6.62E-11 0.781639749 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0071020///post-spliceosomal complex "GO:0000350///generation of catalytic spliceosome for second transesterification step+++GO:0000389///mRNA 3'-splice site recognition+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 57908 57908 'Zfp318' mRNA 501 521 388 3.39 3.21 2.4 2.08 1.54 2.36 3 1.993333333 373 279 387 470 346.3333333 0.004368857 -0.448583317 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity "GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051321///meiotic cell cycle" 57912 57912 'Cdc42se1' mRNA 2306.13 2315.79 2184.21 45.33 44.64 45.43 66.67 67.17 70.44 45.13333333 68.09333333 3952.92 3877.36 4015.85 2268.71 3948.71 7.82E-40 0.788311601 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030054///cell junction GO:0031267///small GTPase binding GO:0006909///phagocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0035023///regulation of Rho protein signal transduction+++GO:0046329///negative regulation of JNK cascade 57913 57913 'Pidd1' mRNA 70 56 58 1.18 0.98 1.06 2.18 2.83 1.96 1.073333333 2.323333333 148 180 128 61.33333333 152 5.03E-07 1.299565219 04064///NF-kappa B signaling pathway+++04115///p53 signaling pathway+++04210///Apoptosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity "GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0016540///protein autoprocessing+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway" 57914 57914 'Crlf2' mRNA 77 110 64 3.42 4.86 3.02 17.35 16.99 17.56 3.766666667 17.3 441 425 436 83.66666667 434 4.79E-39 2.369189438 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004896///cytokine receptor activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032754///positive regulation of interleukin-5 production+++GO:0033005///positive regulation of mast cell activation+++GO:0035745///T-helper 2 cell cytokine production+++GO:1904894///positive regulation of STAT cascade 57915 57915 'Tbc1d1' mRNA 392 344 346 3.77 3.31 3.58 6.95 6.53 6.6 3.553333333 6.693333333 781 755 745 360.6666667 760.3333333 1.72E-21 1.06437175 04152///AMPK signaling pathway "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030688///preribosome, small subunit precursor" GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000469///cleavage involved in rRNA processing+++GO:0006886///intracellular protein transport+++GO:0007601///visual perception+++GO:0030490///maturation of SSU-rRNA+++GO:0032880///regulation of protein localization+++GO:0042274///ribosomal small subunit biogenesis+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090630///activation of GTPase activity" 57916 57916 'Tnfrsf13b' mRNA 54 59 37 1.13 1.22 0.82 7.54 7.05 6.09 1.056666667 6.893333333 413 378 326 50 372.3333333 5.19E-45 2.889022464 04060///Cytokine-cytokine receptor interaction+++04672///Intestinal immune network for IgA production+++05340///Primary immunodeficiency GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001782///B cell homeostasis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0030889///negative regulation of B cell proliferation 58172 58172 'Sertad2' mRNA 2225 2247 1924 20.54 20.08 18.41 12.02 10.71 12.12 19.67666667 11.61666667 1522 1313 1473 2132 1436 3.30E-14 -0.580242629 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0140110///transcription regulator activity "GO:0030308///negative regulation of cell growth+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048096///chromatin-mediated maintenance of transcription" 58175 58175 'Rgs20' mRNA 39 38 44 1.04 0.78 0.89 2.83 2.33 3.23 0.903333333 2.796666667 121 106 137 40.33333333 121.3333333 4.07E-08 1.57415765 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane GO:0005096///GTPase activator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0050790///regulation of catalytic activity 58176 58176 'Rhbg' mRNA 3 4 1 0.09 0.12 0.03 0.4 0.08 0.26 0.08 0.246666667 14 3 9 2.666666667 8.666666667 0.173722056 1.694048005 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014731///spectrin-associated cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0046658///anchored component of plasma membrane GO:0008519///ammonium transmembrane transporter activity+++GO:0030506///ankyrin binding+++GO:0051087///chaperone binding GO:0015696///ammonium transport+++GO:0070634///transepithelial ammonium transport+++GO:0072488///ammonium transmembrane transport 58178 58178 'Sorcs1' mRNA 580 669 528 5.32 5.74 5.08 1.34 1.52 1.61 5.38 1.49 186 177 192 592.3333333 185 1.37E-35 -1.687380215 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0006892///post-Golgi vesicle-mediated transport 58179 58179 'Klrc3' mRNA 0 0 1 0 0 0.02 0.03 0.19 0.02 0.006666667 0.08 2 8 1 0.333333333 3.666666667 0.142276684 3.355757084 GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004888///transmembrane signaling receptor activity+++GO:0023024///MHC class I protein complex binding+++GO:1990405///protein antigen binding GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002228///natural killer cell mediated immunity+++GO:0043323///positive regulation of natural killer cell degranulation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity 58180 58180 'Hic2' mRNA 197 215 145 1.65 1.77 1.29 0.58 0.75 0.68 1.57 0.67 80 101 91 185.6666667 90.66666667 5.96E-06 -1.037098083 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 58182 58182 'Prokr1' mRNA 6 15 10 0.08 0.19 0.14 0.57 0.61 0.7 0.136666667 0.626666667 50 52 60 10.33333333 54 1.16E-06 2.377011536 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007623///circadian rhythm+++GO:0043066///negative regulation of apoptotic process+++GO:0060976///coronary vasculature development 58184 58184 'Cnot9' mRNA 1135 1146 1072 19.5 19.16 19.53 21.79 20.95 21.52 19.39666667 21.42 1451 1375 1381 1117.666667 1402.333333 7.79E-05 0.31591139 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex+++GO:0032991///protein-containing complex GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0019904///protein domain specific binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0042803///protein homodimerization activity "GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031047///gene silencing by RNA+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated" 58185 58185 'Rsad2' mRNA 197 239 171 2.82 3.36 2.59 13.46 12.56 15.92 2.923333333 13.98 1083 987 1241 202.3333333 1103.666667 4.02E-80 2.439754545 05160///Hepatitis C+++05164///Influenza A GO:0001650///fibrillar center+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0016020///membrane "GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0001503///ossification+++GO:0002376///immune system process+++GO:0009615///response to virus+++GO:0030278///regulation of ossification+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0035710///CD4-positive, alpha-beta T cell activation+++GO:0043367///CD4-positive, alpha-beta T cell differentiation+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0050709///negative regulation of protein secretion+++GO:0050778///positive regulation of immune response+++GO:0051607///defense response to virus+++GO:2000553///positive regulation of T-helper 2 cell cytokine production" 58186 58186 'Rad18' mRNA 81 61 60 1.77 1.32 1.42 2.09 2.87 2.65 1.503333333 2.536666667 108 145 128 67.33333333 127 8.74E-04 0.908188738 GO:0000785///chromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0035861///site of double-strand break+++GO:0042405///nuclear inclusion body+++GO:0097505///Rad6-Rad18 complex GO:0000403///Y-form DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006281///DNA repair+++GO:0006301///postreplication repair+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination+++GO:0045910///negative regulation of DNA recombination+++GO:0051865///protein autoubiquitination+++GO:0051984///positive regulation of chromosome segregation+++GO:0060548///negative regulation of cell death 58187 58187 'Cldn10' mRNA 262 245 268 17.93 16.62 19.53 8.43 8.65 8.53 18.02666667 8.536666667 141 141 137 258.3333333 139.6666667 5.36E-07 -0.901078262 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0043269///regulation of ion transport+++GO:0070830///bicellular tight junction assembly 58188 58188 'Vstm2b' mRNA 33 40 40 1.27 1.5 1.73 1.36 1.75 1.35 1.5 1.486666667 41 51 40 37.66666667 44 0.674421927 0.212214426 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 58193 58193 'Extl2' mRNA 1196 1334 1306 22.68 24.85 26.19 11.7 12.12 12.32 24.57333333 12.04666667 703 714 725 1278.666667 714 1.65E-19 -0.853366825 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0001888///glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0005539///glycosaminoglycan binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0035248///alpha-1,4-N-acetylgalactosaminyltransferase activity+++GO:0046872///metal ion binding+++GO:0047237///glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity" GO:0006044///N-acetylglucosamine metabolic process+++GO:0006486///protein glycosylation+++GO:0019276///UDP-N-acetylgalactosamine metabolic process 58194 58194 'Sh3kbp1' mRNA 273 225 241 2.82 2.33 2.65 8.18 8.33 7.9 2.6 8.136666667 897 895 848 246.3333333 880 1.34E-53 1.824957321 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0031625///ubiquitin protein ligase binding GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0007010///cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0050871///positive regulation of B cell activation 58198 58198 'Sall1' mRNA 760 826 698 7.73 8.3 7.52 1.75 1.55 1.63 7.85 1.643333333 197 174 178 761.3333333 183 1.47E-62 -2.066855749 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010369///chromocenter+++GO:0016581///NuRD complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0003281///ventricular septum development+++GO:0003337///mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0003340///negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0008406///gonad development+++GO:0021553///olfactory nerve development+++GO:0021772///olfactory bulb development+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0021915///neural tube development+++GO:0021983///pituitary gland development+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030325///adrenal gland development+++GO:0031129///inductive cell-cell signaling+++GO:0035136///forelimb morphogenesis+++GO:0035137///hindlimb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0045666///positive regulation of neuron differentiation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048566///embryonic digestive tract development+++GO:0060173///limb development+++GO:0061034///olfactory bulb mitral cell layer development+++GO:0072073///kidney epithelium development+++GO:0072092///ureteric bud invasion+++GO:0072309///mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000381///negative regulation of mesoderm development+++GO:2000384///negative regulation of ectoderm development" 58200 58200 'Ppp1r1a' mRNA 5944 5976 4569 277.89 275.79 226.63 155.85 196.09 175.42 260.1033333 175.7866667 3827 4697 4166 5496.333333 4230 3.98E-05 -0.381760369 04261///Adrenergic signaling in cardiomyocytes+++04720///Long-term potentiation GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity 58202 58202 'Nelfb' mRNA 2907 3115 2978 60.11 63.5 65.55 49.73 51.02 50.32 63.05333333 50.35666667 2751 2762 2692 3000 2735 0.042622367 -0.145428069 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0032021///NELF complex GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0008283///cell proliferation+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation+++GO:2000737///negative regulation of stem cell differentiation" 58203 58203 'Zbp1' mRNA 107 158 132 6.26 9.14 8.96 58.52 56.62 59.93 8.12 58.35666667 1071 997 1087 132.3333333 1051.666667 3.27E-111 2.979077722 04217///Necroptosis+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003692///left-handed Z-DNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0012501///programmed cell death+++GO:0016032///viral process+++GO:0043065///positive regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0060545///positive regulation of necroptotic process+++GO:0070269///pyroptosis+++GO:2000659///regulation of interleukin-1-mediated signaling pathway 58205 58205 'Pdcd1lg2' mRNA 5 4 0 0.08 0.06 0 0.08 0.04 0.09 0.046666667 0.07 6 3 6 3 5 0.659116461 0.748763792 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0031295///T cell costimulation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0071222///cellular response to lipopolysaccharide 58206 58206 'Zbtb32' mRNA 15 22 18 0.52 0.7 0.78 0.76 0.59 0.92 0.666666667 0.756666667 37 21 31 18.33333333 29.66666667 0.239071119 0.679576881 GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001817///regulation of cytokine production+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030097///hemopoiesis+++GO:0042098///T cell proliferation 58207 58207 'Slc43a3' mRNA 301 266 287 6.63 5.86 6.73 13.01 12.37 12.48 6.406666667 12.62 676 625 634 284.6666667 645 1.72E-21 1.16672354 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 58208 58208 'Bcl11b' mRNA 23 19 6 0.17 0.11 0.04 0.1 0.06 0.07 0.106666667 0.076666667 16 11 13 16 13.33333333 0.781885402 -0.258866497 05202///Transcriptional misregulation in cancer GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection "GO:0000166///nucleotide binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0003334///keratinocyte development+++GO:0003382///epithelial cell morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0007409///axonogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0009791///post-embryonic development+++GO:0010468///regulation of gene expression+++GO:0010837///regulation of keratinocyte proliferation+++GO:0019216///regulation of lipid metabolic process+++GO:0021773///striatal medium spiny neuron differentiation+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0021953///central nervous system neuron differentiation+++GO:0031077///post-embryonic camera-type eye development+++GO:0033077///T cell differentiation in thymus+++GO:0033153///T cell receptor V(D)J recombination+++GO:0035701///hematopoietic stem cell migration+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043066///negative regulation of apoptotic process+++GO:0043368///positive T cell selection+++GO:0043588///skin development+++GO:0045664///regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046632///alpha-beta T cell differentiation+++GO:0048538///thymus development+++GO:0071678///olfactory bulb axon guidance+++GO:0097535///lymphoid lineage cell migration into thymus 58210 58210 'Sectm1b' mRNA 7 3 8 0.18 0.07 0.2 0.07 0.25 0.17 0.15 0.163333333 3 11 8 6 7.333333333 0.849236452 0.274461048 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity GO:0006955///immune response+++GO:0007165///signal transduction 58212 58212 'Srrm3' mRNA 336.19 347.43 251.92 8.63 8.58 7.54 0.62 0.51 0.55 8.25 0.56 43.62 48.28 45.54 311.8466667 45.81333333 2.77E-38 -2.784951704 GO:0005575///cellular_component GO:0003729///mRNA binding GO:0008150///biological_process 58217 58217 'Trem1' mRNA 13 22 12 0.24 0.8 0.23 2.74 2.24 3.14 0.423333333 2.706666667 172 137 161 15.66666667 156.6666667 4.57E-24 3.313153665 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity+++GO:0097110///scaffold protein binding GO:0001816///cytokine production+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002250///adaptive immune response+++GO:0002367///cytokine production involved in immune response+++GO:0002376///immune system process+++GO:0002526///acute inflammatory response+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0016477///cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0032602///chemokine production+++GO:0045087///innate immune response+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0072672///neutrophil extravasation 58218 58218 'Trem3' mRNA 1 6 6 0.06 0.4 0.4 1.18 0.97 1.74 0.286666667 1.296666667 21 17 31 4.333333333 23 0.002538423 2.390143016 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001530///lipopolysaccharide binding+++GO:0005515///protein binding+++GO:0042834///peptidoglycan binding+++GO:0070891///lipoteichoic acid binding GO:0001816///cytokine production+++GO:0002367///cytokine production involved in immune response+++GO:0016477///cell migration+++GO:0030593///neutrophil chemotaxis+++GO:0032602///chemokine production+++GO:0045089///positive regulation of innate immune response+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0072672///neutrophil extravasation 58220 58220 'Pard6b' mRNA 263 251 203 4.22 3.96 3.45 2.03 1.55 2.27 3.876666667 1.95 146 109 158 239 137.6666667 6.10E-05 -0.804890382 04015///Rap1 signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell GO:0005080///protein kinase C binding+++GO:0005515///protein binding GO:0007043///cell-cell junction assembly+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0007163///establishment or maintenance of cell polarity+++GO:0051301///cell division+++GO:0060341///regulation of cellular localization+++GO:0065003///protein-containing complex assembly 58222 58222 'Rab37' mRNA 458 400 424 11.75 10.04 11.55 10.09 10.72 9.97 11.11333333 10.26 453 469 434 427.3333333 452 0.688945631 0.068720362 GO:0005768///endosome+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0015031///protein transport 58223 58223 'Mmp19' mRNA 40.11 42.15 55.32 0.67 0.66 0.94 7.59 7.14 8.42 0.756666667 7.716666667 545.84 502.48 585.57 45.86 544.63 7.21E-79 3.559548708 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0031225///anchored component of membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0001541///ovarian follicle development+++GO:0001542///ovulation from ovarian follicle+++GO:0001554///luteolysis+++GO:0006508///proteolysis+++GO:0007275///multicellular organism development+++GO:0009725///response to hormone+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process+++GO:0051591///response to cAMP 58226 58226 'Cacna1h' mRNA 7 11 6.55 0.04 0.07 0.04 0.08 0.07 0.1 0.05 0.083333333 14 13 17 8.183333333 14.66666667 0.296112646 0.870332529 04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04713///Circadian entrainment+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04929///GnRH secretion+++04934///Cushing syndrome GO:0001518///voltage-gated sodium channel complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0008332///low voltage-gated calcium channel activity+++GO:0046872///metal ion binding+++GO:0097110///scaffold protein binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0019228///neuronal action potential+++GO:0019233///sensory perception of pain+++GO:0032342///aldosterone biosynthetic process+++GO:0032870///cellular response to hormone stimulus+++GO:0034220///ion transmembrane transport+++GO:0034651///cortisol biosynthetic process+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0035865///cellular response to potassium ion+++GO:0042391///regulation of membrane potential+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0086010///membrane depolarization during action potential+++GO:0098662///inorganic cation transmembrane transport+++GO:0106134///positive regulation of cardiac muscle cell contraction+++GO:2000344///positive regulation of acrosome reaction 58227 58227 'Fam184b' mRNA 326 356 356 4.26 4.58 4.94 2.85 2.87 2.97 4.593333333 2.896666667 251 247 253 346 250.3333333 0.001654589 -0.480017881 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 58229 58229 'Efcc1' mRNA 592.89 677.06 358.68 7.82 8.9 3.92 2.4 3.76 3.17 6.88 3.11 275 317.23 297.25 542.8766667 296.4933333 1.44E-06 -0.87003599 GO:0005829///cytosol GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 58230 58230 'Rnf8' mRNA 1088 1150 1142 29.69 30.91 33.06 20.27 20.78 20.18 31.22 20.41 854 855 823 1126.666667 844 3.68E-06 -0.429510154 "GO:0000151///ubiquitin ligase complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0035861///site of double-strand break" GO:0003682///chromatin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007286///spermatid development+++GO:0010212///response to ionizing radiation+++GO:0016567///protein ubiquitination+++GO:0033522///histone H2A ubiquitination+++GO:0033523///histone H2B ubiquitination+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0043486///histone exchange+++GO:0045190///isotype switching+++GO:0045739///positive regulation of DNA repair+++GO:0051301///cell division+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070535///histone H2A K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination" 58231 58231 'Stk4' mRNA 844 785 763 8.79 7.88 8.45 9.54 10.08 8.77 8.373333333 9.463333333 1013 1063 960 797.3333333 1012 6.98E-04 0.333117079 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++05223///Non-small cell lung cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005773///vacuole+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0000902///cell morphogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001841///neural tube formation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003157///endocardium development+++GO:0006468///protein phosphorylation+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0007417///central nervous system development+++GO:0007566///embryo implantation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010758///regulation of macrophage chemotaxis+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030216///keratinocyte differentiation+++GO:0030317///flagellated sperm motility+++GO:0030879///mammary gland development+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032092///positive regulation of protein binding+++GO:0032147///activation of protein kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0035329///hippo signaling+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046621///negative regulation of organ growth+++GO:0046777///protein autophosphorylation+++GO:0050821///protein stabilization+++GO:0060215///primitive hemopoiesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0060763///mammary duct terminal end bud growth+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development+++GO:0071456///cellular response to hypoxia+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097284///hepatocyte apoptotic process+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:1904237///positive regulation of substrate-dependent cell migration, cell attachment to substrate+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:2000479///regulation of cAMP-dependent protein kinase activity" 58233 58233 'Dnaja4' mRNA 1183 1283 1021 21.74 23.14 20.01 5.27 5.06 4.75 21.63 5.026666667 329 308 287 1162.333333 308 4.25E-73 -1.924571172 GO:0005829///cytosol+++GO:0016020///membrane GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0009408///response to heat+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0042026///protein refolding+++GO:0090084///negative regulation of inclusion body assembly 58234 58234 'Shank3' mRNA 18 22 26 0.13 0.15 0.2 0.27 0.18 0.2 0.16 0.216666667 47 29 34 22 36.66666667 0.164177399 0.716016237 04724///Glutamatergic synapse "GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0044309///neuron spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0060170///ciliary membrane+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0017124///SH3 domain binding+++GO:0030160///GKAP/Homer scaffold activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:0098919///structural constituent of postsynaptic density "GO:0000165///MAPK cascade+++GO:0001838///embryonic epithelial tube formation+++GO:0007416///synapse assembly+++GO:0007611///learning or memory+++GO:0007612///learning+++GO:0007613///memory+++GO:0007626///locomotory behavior+++GO:0008306///associative learning+++GO:0010467///gene expression+++GO:0014009///glial cell proliferation+++GO:0021773///striatal medium spiny neuron differentiation+++GO:0030534///adult behavior+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0035176///social behavior+++GO:0035640///exploration behavior+++GO:0035641///locomotory exploration behavior+++GO:0040011///locomotion+++GO:0042297///vocal learning+++GO:0045794///negative regulation of cell volume+++GO:0048167///regulation of synaptic plasticity+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:0048854///brain morphogenesis+++GO:0050807///regulation of synapse organization+++GO:0050885///neuromuscular process controlling balance+++GO:0051124///synaptic growth at neuromuscular junction+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0060997///dendritic spine morphogenesis+++GO:0060999///positive regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0061351///neural precursor cell proliferation+++GO:0071625///vocalization behavior+++GO:0097107///postsynaptic density assembly+++GO:0097113///AMPA glutamate receptor clustering+++GO:0097114///NMDA glutamate receptor clustering+++GO:0097117///guanylate kinase-associated protein clustering+++GO:0097396///response to interleukin-17+++GO:0099562///maintenance of postsynaptic density structure+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1900451///positive regulation of glutamate receptor signaling pathway+++GO:1900452///regulation of long-term synaptic depression+++GO:1904717///regulation of AMPA glutamate receptor clustering+++GO:2000311///regulation of AMPA receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000821///regulation of grooming behavior+++GO:2000822///regulation of behavioral fear response+++GO:2000969///positive regulation of AMPA receptor activity" 58235 58235 'Nectin1' mRNA 227 248 83 2.12 2.28 0.82 0.89 0.69 0.74 1.74 0.773333333 109 83 88 186 93.33333333 0.002041837 -0.98879039 04514///Cell adhesion molecules+++04520///Adherens junction+++05168///Herpes simplex virus 1 infection GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032584///growth cone membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0099059///integral component of presynaptic active zone membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046790///virion binding+++GO:0050839///cell adhesion molecule binding GO:0002089///lens morphogenesis in camera-type eye+++GO:0002934///desmosome organization+++GO:0006826///iron ion transport+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007411///axon guidance+++GO:0016032///viral process+++GO:0019062///virion attachment to host cell+++GO:0046718///viral entry into host cell+++GO:0048593///camera-type eye morphogenesis+++GO:0051963///regulation of synapse assembly+++GO:0060041///retina development in camera-type eye+++GO:0070166///enamel mineralization+++GO:0098609///cell-cell adhesion+++GO:1902414///protein localization to cell junction 58237 58237 'Nkain4' mRNA 93 121 104 6.28 8.21 7.29 6.43 5.63 6.95 7.26 6.336666667 109 94 113 106 105.3333333 0.950946368 -0.020911397 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002028///regulation of sodium ion transport 58238 58238 'Fam181b' mRNA 441 441 435 13.75 13.55 14.39 13.29 12.67 11.24 13.89666667 12.4 490 456 401 439 449 0.907423123 0.019569336 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 58239 58239 'Dexi' mRNA 127.66 101.42 88.43 5.5 4.31 4.04 3.46 3.94 4.58 4.616666667 3.993333333 92.22 102.44 118.07 105.8366667 104.2433333 0.942680601 -0.024982001 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 58240 58240 'Hs1bp3' mRNA 588 606 580 11.09 10.94 11.45 13.13 12.33 13.91 11.16 13.12333333 813 747 826 591.3333333 795.3333333 5.98E-05 0.415485742 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding GO:0007166///cell surface receptor signaling pathway+++GO:0030217///T cell differentiation+++GO:0042981///regulation of apoptotic process 58242 58242 'Nudt11' mRNA 32.29 35.57 23.59 0.68 0.74 0.53 0.45 0.93 0.73 0.65 0.703333333 24.4 49.22 38.65 30.48333333 37.42333333 0.596918197 0.303340171 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000298///endopolyphosphatase activity+++GO:0008486///diphosphoinositol-polyphosphate diphosphatase activity+++GO:0034431///bis(5'-adenosyl)-hexaphosphatase activity+++GO:0034432///bis(5'-adenosyl)-pentaphosphatase activity+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0052840///inositol diphosphate tetrakisphosphate diphosphatase activity+++GO:0052842///inositol diphosphate pentakisphosphate diphosphatase activity GO:0071543///diphosphoinositol polyphosphate metabolic process+++GO:1901907///diadenosine pentaphosphate catabolic process+++GO:1901909///diadenosine hexaphosphate catabolic process+++GO:1901911///adenosine 5'-(hexahydrogen pentaphosphate) catabolic process 58243 58243 'Nap1l5' mRNA 202 175 214 6.11 5.22 6.87 3.79 4.18 3.94 6.066666667 3.97 144 155 145 197 148 0.043159309 -0.42760932 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0008150///biological_process 58244 58244 'Stx6' mRNA 1511 1565 1282 32.65 33.47 29.22 25.19 26.95 27 31.78 26.38 1329 1395 1388 1452.666667 1370.666667 0.352200633 -0.091577002 04130///SNARE interactions in vesicular transport GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0019905///syntaxin binding "GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0016189///synaptic vesicle to endosome fusion+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling+++GO:0032880///regulation of protein localization+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0048278///vesicle docking+++GO:0061025///membrane fusion+++GO:0090161///Golgi ribbon formation+++GO:1903827///regulation of cellular protein localization" 58245 58245 'Gpr180' mRNA 951 984 754 25.48 26.13 21.81 20.54 22.25 22.29 24.47333333 21.69333333 869 932 906 896.3333333 902.3333333 0.986952097 0.00342716 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 58246 58246 'Slc35b4' mRNA 1024 1144 1001 14.47 15.91 14.87 17.4 15.95 16.23 15.08333333 16.52666667 1427 1291 1289 1056.333333 1335.666667 1.61E-04 0.327261327 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005462///UDP-N-acetylglucosamine transmembrane transporter activity+++GO:0005464///UDP-xylose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006111///regulation of gluconeogenesis+++GO:0008643///carbohydrate transport+++GO:0015790///UDP-xylose transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990569///UDP-N-acetylglucosamine transmembrane transport 58248 58248 '1700123O20Rik' mRNA 730.86 762.8 691.97 34.31 36.29 35.96 40.82 41.01 41.09 35.52 40.97333333 945.44 932.98 942.8 728.5433333 940.4066667 1.34E-04 0.358238595 GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 58249 58249 'Fibp' mRNA 861 926 832 43.14 45.82 44.36 47.39 47.15 47.13 44.44 47.22333333 1085 1056 1044 873 1061.666667 0.002792507 0.271450773 GO:0005634///nucleus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016607///nuclear speck GO:0017134///fibroblast growth factor binding 58250 58250 'Chst11' mRNA 513 605 504 4.85 5.72 5.12 5.59 5.37 5.62 5.23 5.526666667 667 622 654 540.6666667 647.6666667 0.034652434 0.250349467 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001537///N-acetylgalactosamine 4-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0047756///chondroitin 4-sulfotransferase activity+++GO:0050659///N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity GO:0001701///in utero embryonic development+++GO:0002063///chondrocyte development+++GO:0005975///carbohydrate metabolic process+++GO:0007585///respiratory gaseous exchange+++GO:0009791///post-embryonic development+++GO:0016051///carbohydrate biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030204///chondroitin sulfate metabolic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0030326///embryonic limb morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0033037///polysaccharide localization+++GO:0036342///post-anal tail morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0042733///embryonic digit morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0048589///developmental growth+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0051216///cartilage development 58251 58251 'Cep295nl' mRNA 13 10 13 0.27 0.19 0.29 0.57 0.3 0.29 0.25 0.386666667 32 18 17 12 22.33333333 0.196491926 0.875405922 GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0030414///peptidase inhibitor activity GO:0046599///regulation of centriole replication+++GO:1905049///negative regulation of metallopeptidase activity 58520 58520 'Erg28' mRNA 1040.78 1004.98 1190.9 40.84 38.8 49.48 40.59 37.98 36.1 43.04 38.22333333 1197.94 1094.97 1035.93 1078.886667 1109.613333 0.869440851 0.023102837 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle "GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0016126///sterol biosynthetic process 58521 58521 'Eid1' mRNA 473 478 434 10.34 10.29 10.07 9.89 8.96 10.21 10.23333333 9.686666667 520 460 520 461.6666667 500 0.472333244 0.103904946 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0035034///histone acetyltransferase regulator activity+++GO:0035035///histone acetyltransferase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0030154///cell differentiation+++GO:0035065///regulation of histone acetylation+++GO:0045595///regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 58522 58522 'Trim54' mRNA 2 0 1 0.08 0 0.04 0.17 0.1 0.17 0.04 0.146666667 5 3 5 1 4.333333333 0.251871399 2.096640333 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0030018///Z disc GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007026///negative regulation of microtubule depolymerization+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation 58523 58523 'Elp2' mRNA 1752 1785 1909 34.71 34.8 40.11 27.8 26.03 26.84 36.54 26.89 1614 1476 1510 1815.333333 1533.333333 0.003404837 -0.258693769 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex+++GO:0033588///Elongator holoenzyme complex GO:0000993///RNA polymerase II complex binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0061133///endopeptidase activator activity GO:0002098///tRNA wobble uridine modification+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0008033///tRNA processing+++GO:0010950///positive regulation of endopeptidase activity+++GO:0043248///proteasome assembly+++GO:0046425///regulation of JAK-STAT cascade 58799 58799 'Crbn' mRNA 1594.2 1611.01 1608.65 21.22 21.09 22.71 13.58 13.46 14.05 21.67333333 13.69666667 1174.34 1137.03 1177.02 1604.62 1162.796667 2.30E-09 -0.477230716 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination+++GO:0031333///negative regulation of protein complex assembly+++GO:0031334///positive regulation of protein complex assembly+++GO:0034766///negative regulation of ion transmembrane transport+++GO:0035641///locomotory exploration behavior+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1902607///negative regulation of large conductance calcium-activated potassium channel activity 58800 58800 'Trpm7' mRNA 1509 1549 1386.54 11.25 11.28 10.9 10.53 9.46 9.41 11.14333333 9.8 1632.1 1436 1417 1481.513333 1495.033333 0.99331619 0.001865688 04217///Necroptosis+++04218///Cellular senescence+++04621///NOD-like receptor signaling pathway+++04978///Mineral absorption GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043196///varicosity GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017022///myosin binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0007613///memory+++GO:0010961///cellular magnesium ion homeostasis+++GO:0012501///programmed cell death+++GO:0016310///phosphorylation+++GO:0016340///calcium-dependent cell-matrix adhesion+++GO:0031032///actomyosin structure organization+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0051262///protein tetramerization+++GO:0055085///transmembrane transport+++GO:0070266///necroptotic process+++GO:0070588///calcium ion transmembrane transport+++GO:0072507///divalent inorganic cation homeostasis+++GO:0098655///cation transmembrane transport 58801 58801 'Pmaip1' mRNA 2 6 6 0.04 0.12 0.13 3.7 3.44 3.21 0.096666667 3.45 204 185 171 4.666666667 186.6666667 2.18E-31 5.308846368 01524///Platinum drug resistance+++04115///p53 signaling pathway+++04210///Apoptosis+++04215///Apoptosis - multiple species+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05210///Colorectal cancer GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0005515///protein binding "GO:0001836///release of cytochrome c from mitochondria+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009411///response to UV+++GO:0010165///response to X-ray+++GO:0010498///proteasomal protein catabolic process+++GO:0010907///positive regulation of glucose metabolic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0042149///cellular response to glucose starvation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042981///regulation of apoptotic process+++GO:0043029///T cell homeostasis+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043331///response to dsRNA+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0051607///defense response to virus+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0072593///reactive oxygen species metabolic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 58802 58802 'Kcnmb4' mRNA 33 59 32 0.88 1.67 1.07 0.62 0.55 0.8 1.206666667 0.656666667 17 18 20 41.33333333 18.33333333 0.017826273 -1.175254203 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0015459///potassium channel regulator activity GO:0001508///action potential+++GO:0005513///detection of calcium ion+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0019228///neuronal action potential+++GO:0071805///potassium ion transmembrane transport 58804 58804 'Cdc42ep5' mRNA 168 162 166 13.25 12.5 14.47 11.47 14.35 14.24 13.40666667 13.35333333 160 197 194 165.3333333 183.6666667 0.567843208 0.141036491 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007254///JNK cascade+++GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly 58805 58805 'Mlxipl' mRNA 913 964 742 13.28 13.63 11.34 7.17 6.91 7.93 12.75 7.336666667 567 537 606 873 570 1.15E-08 -0.622285829 04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0035538///carbohydrate response element binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006110///regulation of glycolytic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006913///nucleocytoplasmic transport+++GO:0008284///positive regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0010255///glucose mediated signaling pathway+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0042593///glucose homeostasis+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0045821///positive regulation of glycolytic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0051726///regulation of cell cycle+++GO:0055089///fatty acid homeostasis+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071333///cellular response to glucose stimulus+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0097009///energy homeostasis" 58807 58807 'Slco1c1' mRNA 1605 1629 1571 27.34 27.3 28.39 33.35 34.69 33.39 27.67666667 33.81 2253 2289 2184 1601.666667 2242 2.93E-11 0.473628149 04919///Thyroid hormone signaling pathway GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015711///organic anion transport+++GO:0015721///bile acid and bile salt transport+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:2000611///positive regulation of thyroid hormone generation 58809 58809 'Rnase4' mRNA 1336.7 1360.57 1182.78 51.2 51.81 47.81 210.36 206.64 202.11 50.27333333 206.37 6352.76 6114.34 5899.25 1293.35 6122.116667 5.74E-298 2.233599409 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0009267///cellular response to starvation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 58810 58810 'Akr1a1' mRNA 16699 16907 16873 704.34 703.58 755.04 847.77 831.82 837.2 720.9866667 838.93 23083 22097 22050 16826.33333 22410 1.99E-14 0.400230474 00010///Glycolysis / Gluconeogenesis+++00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++01240///Biosynthesis of cofactors+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0045202///synapse "GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0019726///mevaldate reductase (NADPH) activity+++GO:0047655///allyl-alcohol dehydrogenase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0047939///L-glucuronate reductase activity+++GO:0047941///glucuronolactone reductase activity+++GO:0047956///glycerol dehydrogenase [NADP+] activity+++GO:1990002///methylglyoxal reductase (NADPH-dependent, acetol producing)" GO:0019853///L-ascorbic acid biosynthetic process+++GO:0042840///D-glucuronate catabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0046185///aldehyde catabolic process+++GO:0110095///cellular detoxification of aldehyde 58859 58859 'Efemp2' mRNA 1964 2121 1996 70.54 74.35 76.14 97.44 102.87 99.71 73.67666667 100.0066667 3092 3182 3079 2027 3117.666667 2.55E-19 0.609732501 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0042803///protein homodimerization activity GO:0035904///aorta development+++GO:0048251///elastic fiber assembly+++GO:0060414///aorta smooth muscle tissue morphogenesis+++GO:0060840///artery development+++GO:0097084///vascular smooth muscle cell development+++GO:1904026///regulation of collagen fibril organization+++GO:1904028///positive regulation of collagen fibril organization+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1904831///positive regulation of aortic smooth muscle cell differentiation+++GO:1905609///positive regulation of smooth muscle cell-matrix adhesion 58860 58860 'Adamdec1' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 58861 58861 'Cysltr1' mRNA 46 42 43 0.8 0.76 0.78 4.9 5.47 5.23 0.78 5.2 322 347 336 43.66666667 335 6.21E-46 2.928930213 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001631///cysteinyl leukotriene receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004974///leukotriene receptor activity+++GO:0005515///protein binding+++GO:0008528///G protein-coupled peptide receptor activity GO:0002437///inflammatory response to antigenic stimulus+++GO:0006816///calcium ion transport+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045907///positive regulation of vasoconstriction+++GO:0061737///leukotriene signaling pathway 58864 58864 'Tssk3' mRNA 43 33 24 1.97 1.36 1.28 0.75 0.34 0.37 1.536666667 0.486666667 19 9 9 33.33333333 12.33333333 0.012489791 -1.444237842 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0048240///sperm capacitation 58865 58865 'Tdh' mRNA 2 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 "00260///Glycine, serine and threonine metabolism" GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008743///L-threonine 3-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding GO:0006567///threonine catabolic process+++GO:0019518///L-threonine catabolic process to glycine 58866 58866 'Treh' mRNA 4 2 12 0.12 0.06 0.36 0.64 0.47 0.25 0.18 0.453333333 26 19 10 6 18.33333333 0.074758071 1.567048148 00500///Starch and sucrose metabolism GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0031225///anchored component of membrane "GO:0004555///alpha,alpha-trehalase activity+++GO:0015927///trehalase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0005991///trehalose metabolic process+++GO:0005993///trehalose catabolic process+++GO:0008152///metabolic process+++GO:0009887///animal organ morphogenesis 58867 58867 'Syngr4' mRNA 1 1 1 0.08 0.03 0.09 0.65 0.24 0.73 0.066666667 0.54 11 7 12 1 10 0.012898695 3.307923699 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031594///neuromuscular junction GO:0003674///molecular_function GO:0008150///biological_process 58869 58869 'Pex5l' mRNA 714 773 630 8.27 8.72 7.12 3.61 2.96 3.14 8.036666667 3.236666667 359 268 306 705.6666667 311 3.24E-21 -1.192750834 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016593///Cdc73/Paf1 complex+++GO:0017071///intracellular cyclic nucleotide activated cation channel complex+++GO:0030425///dendrite+++GO:0043235///receptor complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0051286///cell tip GO:0000268///peroxisome targeting sequence binding+++GO:0005052///peroxisome matrix targeting signal-1 binding+++GO:0005221///intracellular cyclic nucleotide activated cation channel activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding "GO:0000038///very long-chain fatty acid metabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0006635///fatty acid beta-oxidation+++GO:0006699///bile acid biosynthetic process+++GO:0007031///peroxisome organization+++GO:0007399///nervous system development+++GO:0016558///protein import into peroxisome matrix+++GO:0016560///protein import into peroxisome matrix, docking+++GO:0031648///protein destabilization+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0042632///cholesterol homeostasis+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0045055///regulated exocytosis+++GO:0045185///maintenance of protein location+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051461///positive regulation of corticotropin secretion+++GO:0098655///cation transmembrane transport" 58875 58875 'Hibadh' mRNA 2557 2660 2460 85.39 87.56 87.15 78.31 79.23 82.28 86.7 79.94 2695 2661 2740 2559 2698.666667 0.388089417 0.065673425 "00280///Valine, leucine and isoleucine degradation" GO:0005739///mitochondrion "GO:0008442///3-hydroxyisobutyrate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0050661///NADP binding+++GO:0051287///NAD binding" GO:0006574///valine catabolic process+++GO:0009083///branched-chain amino acid catabolic process 58887 58887 'Repin1' mRNA 1645 1573 1459 29.11 27.28 27.43 14.59 17.08 14.58 27.94 15.41666667 942 1079 914 1559 978.3333333 1.12E-13 -0.681561867 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0022626///cytosolic ribosome+++GO:0031965///nuclear membrane GO:0003677///DNA binding+++GO:0043035///chromatin insulator sequence binding+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:2000191///regulation of fatty acid transport 58909 58909 'Fam13a' mRNA 1117 1117 990 14 13.76 13.16 4.47 4.6 4.57 13.64 4.546666667 411 413 407 1074.666667 410.3333333 3.95E-47 -1.398761333 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 58911 58911 'Sumf1' mRNA 1436 1522 637 30.89 32.23 14.56 18.36 36.9 30.18 25.89333333 28.48 974 1884 1536 1198.333333 1464.666667 0.614321971 0.302842444 04142///Lysosome GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0120147///Formylglycine-generating oxidase activity+++GO:1903135///cupric ion binding GO:0018158///protein oxidation+++GO:0043687///post-translational protein modification 58916 58916 'Myot' mRNA 274 301 342 7.15 7.75 9.43 1.32 2.22 1.81 8.11 1.783333333 58 95 78 305.6666667 77 4.89E-20 -2.002349632 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0030424///axon+++GO:0042383///sarcolemma GO:0003779///actin binding+++GO:0051393///alpha-actinin binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0070593///dendrite self-avoidance 58988 58988 'Rps6kb2' mRNA 887 860 790 28.34 26.9 26.6 22.44 22.49 21.72 27.28 22.21666667 804 787 761 845.6666667 784 0.267390166 -0.11975343 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04350///TGF-beta signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04931///Insulin resistance+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042277///peptide binding GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031929///TOR signaling+++GO:0043491///protein kinase B signaling+++GO:0045948///positive regulation of translational initiation 58991 58991 'Ghrl' mRNA 3 0 4 0.48 0 0.69 0.57 1.14 0.64 0.39 0.783333333 4 6 4 2.333333333 4.666666667 0.572826341 0.968415814 "04024///cAMP signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04935///Growth hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0030424///axon+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0070195///growth hormone receptor complex+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0001664///G protein-coupled receptor binding+++GO:0004896///cytokine receptor activity+++GO:0004903///growth hormone receptor activity+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0016608///growth hormone-releasing hormone activity+++GO:0017046///peptide hormone binding+++GO:0019838///growth factor binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0019955///cytokine binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0031768///ghrelin receptor binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0000187///activation of MAPK activity+++GO:0001696///gastric acid secretion+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007259///JAK-STAT cascade+++GO:0008154///actin polymerization or depolymerization+++GO:0008343///adult feeding behavior+++GO:0008542///visual learning+++GO:0009725///response to hormone+++GO:0009755///hormone-mediated signaling pathway+++GO:0016358///dendrite development+++GO:0019221///cytokine-mediated signaling pathway+++GO:0019530///taurine metabolic process+++GO:0031667///response to nutrient levels+++GO:0032024///positive regulation of insulin secretion+++GO:0032094///response to food+++GO:0032095///regulation of response to food+++GO:0032097///positive regulation of response to food+++GO:0032100///positive regulation of appetite+++GO:0032355///response to estradiol+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032869///cellular response to insulin stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0034097///response to cytokine+++GO:0035483///gastric emptying+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0040010///positive regulation of growth rate+++GO:0040013///negative regulation of locomotion+++GO:0040014///regulation of multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042127///regulation of cell proliferation+++GO:0042322///negative regulation of circadian sleep/wake cycle, REM sleep+++GO:0042445///hormone metabolic process+++GO:0042976///activation of Janus kinase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0043278///response to morphine+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043434///response to peptide hormone+++GO:0043627///response to estrogen+++GO:0045597///positive regulation of cell differentiation+++GO:0045927///positive regulation of growth+++GO:0046010///positive regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046676///negative regulation of insulin secretion+++GO:0046697///decidualization+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0050728///negative regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051384///response to glucocorticoid+++GO:0051461///positive regulation of corticotropin secretion+++GO:0051464///positive regulation of cortisol secretion+++GO:0051602///response to electrical stimulus+++GO:0051965///positive regulation of synapse assembly+++GO:0051969///regulation of transmission of nerve impulse+++GO:0060079///excitatory postsynaptic potential+++GO:0060124///positive regulation of growth hormone secretion+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0060396///growth hormone receptor signaling pathway+++GO:0060416///response to growth hormone+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0070555///response to interleukin-1+++GO:0097009///energy homeostasis+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:0099175///regulation of postsynapse organization+++GO:0120058///positive regulation of small intestinal transit+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901215///negative regulation of neuron death+++GO:1903012///positive regulation of bone development+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:1904000///positive regulation of eating behavior+++GO:1904179///positive regulation of adipose tissue development+++GO:1904306///positive regulation of gastro-intestinal system smooth muscle contraction+++GO:1904346///positive regulation of gastric mucosal blood circulation+++GO:1904349///positive regulation of small intestine smooth muscle contraction+++GO:1905333///regulation of gastric motility+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:2000253///positive regulation of feeding behavior" 58992 58992 'F12' mRNA 27 32 24 0.78 0.91 0.74 0.08 0.13 0.16 0.81 0.123333333 3 5 6 27.66666667 4.666666667 1.92E-04 -2.572676432 04610///Complement and coagulation cascades GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005791///rough endoplasmic reticulum GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0002353///plasma kallikrein-kinin cascade+++GO:0002542///Factor XII activation+++GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0010756///positive regulation of plasminogen activation+++GO:0016485///protein processing+++GO:0016540///protein autoprocessing+++GO:0030194///positive regulation of blood coagulation+++GO:0031638///zymogen activation+++GO:0042730///fibrinolysis+++GO:0051788///response to misfolded protein+++GO:0051919///positive regulation of fibrinolysis 58994 58994 'Smpd3' mRNA 109 137 161 1.14 1.41 1.78 0.87 0.92 0.92 1.443333333 0.903333333 96 98 98 135.6666667 97.33333333 0.062262509 -0.496801235 00600///Sphingolipid metabolism GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0001786///phosphatidylserine binding+++GO:0003824///catalytic activity+++GO:0004620///phospholipase activity+++GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061751///neutral sphingomyelin phosphodiesterase activity+++GO:0070300///phosphatidic acid binding GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0001932///regulation of protein phosphorylation+++GO:0001958///endochondral ossification+++GO:0002063///chondrocyte development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002685///regulation of leukocyte migration+++GO:0003433///chondrocyte development involved in endochondral bone morphogenesis+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006684///sphingomyelin metabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0014824///artery smooth muscle contraction+++GO:0015774///polysaccharide transport+++GO:0030072///peptide hormone secretion+++GO:0030282///bone mineralization+++GO:0030324///lung development+++GO:0030509///BMP signaling pathway+++GO:0032963///collagen metabolic process+++GO:0034614///cellular response to reactive oxygen species+++GO:0035264///multicellular organism growth+++GO:0043491///protein kinase B signaling+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048286///lung alveolus development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051216///cartilage development+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0060348///bone development+++GO:0060541///respiratory system development+++GO:0061035///regulation of cartilage development+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070314///G1 to G0 transition+++GO:0071286///cellular response to magnesium ion+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071461///cellular response to redox state+++GO:0071897///DNA biosynthetic process+++GO:0085029///extracellular matrix assembly+++GO:0090494///dopamine uptake+++GO:0090520///sphingolipid mediated signaling pathway+++GO:0097187///dentinogenesis+++GO:0098868///bone growth+++GO:0140014///mitotic nuclear division+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:1900125///regulation of hyaluronan biosynthetic process+++GO:1900126///negative regulation of hyaluronan biosynthetic process+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901653///cellular response to peptide+++GO:1903543///positive regulation of exosomal secretion+++GO:2000304///positive regulation of ceramide biosynthetic process 58996 58996 'Arhgap23' mRNA 495 450 401 4.44 3.99 3.77 4.3 4.15 4.82 4.066666667 4.423333333 553 517 591 448.6666667 553.6666667 0.022370506 0.293882016 GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 58998 58998 'Nectin3' mRNA 347 364 324 6.42 6.25 5.77 3.92 3.25 4.12 6.146666667 3.763333333 248 207 262 345 239 5.22E-04 -0.540813608 04514///Cell adhesion molecules+++04520///Adherens junction GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding GO:0002089///lens morphogenesis in camera-type eye+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0061951///establishment of protein localization to plasma membrane+++GO:0098609///cell-cell adhesion+++GO:1902414///protein localization to cell junction 59001 59001 'Pole3' mRNA 329 290 282 41.72 36.62 37.96 39.13 38.2 36.91 38.76666667 38.08 352 334 320 300.3333333 335.3333333 0.385064596 0.147783829 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0008622///epsilon DNA polymerase complex+++GO:0008623///CHRAC GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031490///chromatin DNA binding+++GO:0046982///protein heterodimerization activity GO:0006272///leading strand elongation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031507///heterochromatin assembly+++GO:0042766///nucleosome mobilization+++GO:0043966///histone H3 acetylation 59002 59002 'Wrap73' mRNA 611 619 593 22.32 22.31 22.95 15.18 16.56 16.62 22.52666667 16.12 477 508 506 607.6666667 497 0.010447108 -0.300988261 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0072686///mitotic spindle+++GO:1990811///MWP complex GO:0005515///protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0030030///cell projection organization+++GO:0090307///mitotic spindle assembly+++GO:1902440///protein localization to mitotic spindle pole body+++GO:1902857///positive regulation of non-motile cilium assembly 59003 59003 'Maea' mRNA 1903 1995 1934 50.52 52.1 54.49 59.42 60.59 58.17 52.37 59.39333333 2576 2568 2444 1944 2529.333333 2.13E-07 0.367527452 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005826///actomyosin contractile ring+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0034657///GID complex GO:0003779///actin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0016567///protein ubiquitination+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043249///erythrocyte maturation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0048821///erythrocyte development+++GO:0048822///enucleate erythrocyte development+++GO:0051301///cell division 59004 59004 'Pias4' mRNA 731 700 615 25.42 24 22.69 19.25 19.23 20.02 24.03666667 19.5 636 620 640 682 632 0.325909089 -0.119261037 04064///NF-kappa B signaling pathway+++04120///Ubiquitin mediated proteolysis+++04630///JAK-STAT signaling pathway+++05418///Fluid shear stress and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:1990234///transferase complex GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061665///SUMO ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007259///JAK-STAT cascade+++GO:0007275///multicellular organism development+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016032///viral process+++GO:0016055///Wnt signaling pathway+++GO:0016925///protein sumoylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033235///positive regulation of protein sumoylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1902174///positive regulation of keratinocyte apoptotic process+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage" 59005 59005 'Trappc2l' mRNA 1247 1277 1212 155.06 158.07 159.97 175.12 199.22 178.31 157.7 184.2166667 1607 1777 1577 1245.333333 1653.666667 3.46E-06 0.398527619 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030008///TRAPP complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport 59006 59006 'Myoz2' mRNA 1 3 0 0.06 0.19 0 0.17 0.46 0.12 0.083333333 0.25 3 8 2 1.333333333 4.333333333 0.351581022 1.724466124 GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc GO:0003779///actin binding+++GO:0031433///telethonin binding+++GO:0051373///FATZ binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0043503///skeletal muscle fiber adaptation+++GO:0045214///sarcomere organization+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 59007 59007 'Ngly1' mRNA 852 894 902 18.79 19.61 20.93 18.57 17.58 17.55 19.77666667 17.9 965 891 873 882.6666667 909.6666667 0.831786779 0.029737242 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0062023///collagen-containing extracellular matrix GO:0000224///peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006516///glycoprotein catabolic process+++GO:0006517///protein deglycosylation+++GO:0071712///ER-associated misfolded protein catabolic process 59008 59008 'Anapc5' mRNA 2765 2764 2859 56.6 55.56 62.5 71.67 77.81 73.69 58.22 74.39 4062 4309 4036 2796 4135.666667 8.42E-15 0.551928117 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04657///IL-17 signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0019903///protein phosphatase binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 59009 59009 'Sh3rf1' mRNA 2078 2150 1545 22.66 23.46 17.98 11.03 10.22 11.53 21.36666667 10.92666667 1213 1052 1178 1924.333333 1147.666667 1.88E-14 -0.751816619 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0001764///neuron migration+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043370///regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0051865///protein autoubiquitination+++GO:2000564///regulation of CD8-positive, alpha-beta T cell proliferation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 59010 59010 'Sqor' mRNA 552 606 518 19.13 20.69 19.17 31.03 32.73 28.61 19.66333333 30.79 1024 1053 914 558.6666667 997 6.43E-16 0.825928813 00920///Sulfur metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane GO:0016491///oxidoreductase activity+++GO:0048038///quinone binding+++GO:0070224///sulfide:quinone oxidoreductase activity+++GO:0071949///FAD binding "GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0070813///hydrogen sulfide metabolic process" 59011 59011 'Myoz1' mRNA 2 1 2 0.09 0.05 0.1 0.82 0.33 0.67 0.08 0.606666667 20 8 16 1.666666667 14.66666667 0.00373334 3.115414873 GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0031143///pseudopodium+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0031433///telethonin binding+++GO:0051373///FATZ binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0042060///wound healing+++GO:0043086///negative regulation of catalytic activity+++GO:0043417///negative regulation of skeletal muscle tissue regeneration+++GO:0043503///skeletal muscle fiber adaptation+++GO:0045214///sarcomere organization+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 59012 59012 'Moxd1' mRNA 63 114 91 1.12 1.99 1.72 16.06 18.77 18.32 1.61 17.71666667 1039 1186 1148 89.33333333 1124.333333 3.26E-122 3.644166156 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030667///secretory granule membrane "GO:0003824///catalytic activity+++GO:0004497///monooxygenase activity+++GO:0004500///dopamine beta-monooxygenase activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0016715///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen+++GO:0046872///metal ion binding" GO:0006589///octopamine biosynthetic process+++GO:0042420///dopamine catabolic process+++GO:0042421///norepinephrine biosynthetic process 59013 59013 'Hnrnph1' mRNA 5786 6022 5628 135.82 138.63 138.9 101.99 94.3 100.72 137.7833333 99.00333333 4914 4373 4650 5812 4645.666667 5.64E-09 -0.335440449 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0098761///cellular response to interleukin-7 59014 59014 'Rrs1' mRNA 406 443 413 11.26 12.1 12.15 18.23 18.6 18.51 11.83666667 18.44666667 756 753 743 420.6666667 750.6666667 1.93E-14 0.824087753 "GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0030687///preribosome, large subunit precursor" GO:0005515///protein binding+++GO:0008097///5S rRNA binding "GO:0000027///ribosomal large subunit assembly+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007080///mitotic metaphase plate congression+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1902570///protein localization to nucleolus" 59015 59015 'Nup160' mRNA 651 737.01 676 5.38 5.88 5.61 5.14 4.68 4.95 5.623333333 4.923333333 706.01 640.01 680.78 688.0033333 675.6 0.789685741 -0.038959357 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031080///nuclear pore outer ring GO:0017056///structural constituent of nuclear pore GO:0006406///mRNA export from nucleus+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0072006///nephron development 59016 59016 'Thap11' mRNA 987 1076 668 30.68 32.96 22.03 15.39 24 22.41 28.55666667 20.6 569 866 802 910.3333333 745.6666667 0.373958724 -0.285234903 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 59020 59020 'Pdzk1' mRNA 2.88 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.96 0 0.749855753 -1.843955659 GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0045121///membrane raft GO:0005124///scavenger receptor binding+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0043495///protein membrane anchor+++GO:0044877///protein-containing complex binding GO:0001701///in utero embryonic development+++GO:0015879///carnitine transport+++GO:0032414///positive regulation of ion transmembrane transporter activity+++GO:0044070///regulation of anion transport+++GO:0072659///protein localization to plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1904064///positive regulation of cation transmembrane transport+++GO:1905477///positive regulation of protein localization to membrane 59021 59021 'Rab2a' mRNA 1496.87 1494.07 1186.99 33.49 32.06 26.31 25.35 24.43 29.19 30.62 26.32333333 1350.55 1235.28 1483.95 1392.643333 1356.593333 0.730600469 -0.045381099 04152///AMPK signaling pathway GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042470///melanosome+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0006886///intracellular protein transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 59022 59022 'Edf1' mRNA 2182 2339 2193 213.28 226.71 227.16 261.76 292.86 273.92 222.3833333 276.18 3065 3339 3093 2238 3165.666667 1.20E-11 0.489529733 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0001094///TFIID-class transcription factor complex binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005516///calmodulin binding "GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043388///positive regulation of DNA binding+++GO:0045893///positive regulation of transcription, DNA-templated" 59024 59024 'Med12' mRNA 1213 1100 890 7.55 6.72 5.87 5.96 5.29 5.75 6.713333333 5.666666667 1103 957 1032 1067.666667 1030.666667 0.664388641 -0.058993588 04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0046966///thyroid hormone receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007492///endoderm development+++GO:0007507///heart development+++GO:0014003///oligodendrocyte development+++GO:0014044///Schwann cell development+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0021510///spinal cord development+++GO:0021915///neural tube development+++GO:0036342///post-anal tail morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0090245///axis elongation involved in somitogenesis+++GO:1990403///embryonic brain development" 59025 59025 'Usp14' mRNA 1278.69 1312.96 1274.18 26.84 27.12 28.73 34.78 33.14 33.34 27.56333333 33.75333333 1870.5 1736.07 1727.42 1288.61 1777.996667 3.06E-09 0.452240864 GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070628///proteasome binding GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007268///chemical synaptic transmission+++GO:0010951///negative regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0050920///regulation of chemotaxis+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:1903070///negative regulation of ER-associated ubiquitin-dependent protein catabolic process 59026 59026 'Huwe1' mRNA 3494 3378 2983 12.28 11.65 11.12 10.08 9.18 9.55 11.68333333 9.603333333 3312 2939 3040 3285 3097 0.199195768 -0.095414252 04120///Ubiquitin mediated proteolysis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007030///Golgi organization+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0030154///cell differentiation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032922///circadian regulation of gene expression+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048511///rhythmic process+++GO:0061025///membrane fusion+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization 59027 59027 'Nampt' mRNA 1731 1765 1786 20.42 20.48 22.35 29.66 27.51 29.69 21.08333333 28.95333333 2894 2622 2806 1760.666667 2774 3.29E-19 0.642181574 00760///Nicotinate and nicotinamide metabolism+++04621///NOD-like receptor signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005125///cytokine activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042802///identical protein binding+++GO:0047280///nicotinamide phosphoribosyltransferase activity+++GO:1901363///heterocyclic compound binding" GO:0001774///microglial cell activation+++GO:0007165///signal transduction+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0007623///circadian rhythm+++GO:0009435///NAD biosynthetic process+++GO:0010507///negative regulation of autophagy+++GO:0014070///response to organic cyclic compound+++GO:0014916///regulation of lung blood pressure+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0032922///circadian regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0070997///neuron death+++GO:0071479///cellular response to ionizing radiation+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:1904646///cellular response to amyloid-beta+++GO:1905377///response to D-galactose+++GO:2000773///negative regulation of cellular senescence 59028 59028 'Rcl1' mRNA 353 412 377 11.28 12.98 12.84 11.79 10.06 12.31 12.36666667 11.38666667 424 353 427 380.6666667 401.3333333 0.739272063 0.063485811 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003824///catalytic activity+++GO:0003963///RNA-3'-phosphate cyclase activity+++GO:0004521///endoribonuclease activity "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0042254///ribosome biogenesis" 59029 59029 'Psmd14' mRNA 1266 1364 1209 48.35 51.38 48.99 69.75 72.02 71.2 49.57333333 70.99 2098 2114 2072 1279.666667 2094.666667 2.77E-22 0.700730427 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex+++GO:0031597///cytosolic proteasome complex" GO:0004175///endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0061133///endopeptidase activator activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070122///isopeptidase activity+++GO:0070628///proteasome binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045471///response to ethanol+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0070536///protein K63-linked deubiquitination 59030 59030 'Mkks' mRNA 787 772 733 14.07 14.07 13.99 16.53 16.53 15.68 14.04333333 16.24666667 1045 1040.99 966 764 1017.33 1.68E-05 0.401468575 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:1902636///kinociliary basal body GO:0000166///nucleotide binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0051082///unfolded protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006457///protein folding+++GO:0007286///spermatid development+++GO:0007608///sensory perception of smell+++GO:0010629///negative regulation of gene expression+++GO:0014824///artery smooth muscle contraction+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030837///negative regulation of actin filament polymerization+++GO:0032502///developmental process+++GO:0033210///leptin-mediated signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0035176///social behavior+++GO:0038108///negative regulation of appetite by leptin-mediated signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042311///vasodilation+++GO:0044321///response to leptin+++GO:0045444///fat cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0045776///negative regulation of blood pressure+++GO:0046907///intracellular transport+++GO:0048854///brain morphogenesis+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051216///cartilage development+++GO:0051492///regulation of stress fiber assembly+++GO:0060271///cilium assembly+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:0060324///face development+++GO:1905515///non-motile cilium assembly 59031 59031 'Chst12' mRNA 491 550 483 15.8 17.49 16.52 23.99 26.41 23.23 16.60333333 24.54333333 856 919 802 508 859 4.12E-12 0.747905154 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0047756///chondroitin 4-sulfotransferase activity GO:0005975///carbohydrate metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0030208///dermatan sulfate biosynthetic process 59032 59032 'Ppp2r3c' mRNA 425.88 406.98 362.17 10.09 9.49 9.05 12.06 12.34 12.45 9.543333333 12.28333333 589.09 583.41 584.38 398.3433333 585.6266667 2.81E-06 0.548011409 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0001782///B cell homeostasis+++GO:0002759///regulation of antimicrobial humoral response+++GO:0030865///cortical cytoskeleton organization+++GO:0032147///activation of protein kinase activity+++GO:0035303///regulation of dephosphorylation+++GO:0043029///T cell homeostasis+++GO:0045579///positive regulation of B cell differentiation+++GO:0048536///spleen development+++GO:0050864///regulation of B cell activation+++GO:0051900///regulation of mitochondrial depolarization 59033 59033 'Slc4a8' mRNA 543 438 533 2.4 1.9 2.5 0.98 0.86 0.88 2.266666667 0.906666667 254 219 222 504.6666667 231.6666667 2.99E-14 -1.139634816 GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032279///asymmetric synapse+++GO:0032280///symmetric synapse+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0043005///neuron projection+++GO:0043195///terminal bouton+++GO:0043679///axon terminus+++GO:0097386///glial cell projection+++GO:0097457///hippocampal mossy fiber+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0015081///sodium ion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0009790///embryo development+++GO:0015701///bicarbonate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050801///ion homeostasis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:2000302///positive regulation of synaptic vesicle exocytosis 59035 59035 'Carm1' mRNA 295.77 271.83 287.31 4.92 4.47 5.04 5.09 4.39 4.82 4.81 4.766666667 348.25 291.34 318.15 284.97 319.2466667 0.393083544 0.15177974 01522///Endocrine resistance GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0035642///histone methyltransferase activity (H3-R17 specific)+++GO:0042054///histone methyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0070577///lysine-acetylated histone binding "GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006479///protein methylation+++GO:0007568///aging+++GO:0008284///positive regulation of cell proliferation+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0032259///methylation+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034969///histone arginine methylation+++GO:0034970///histone H3-R2 methylation+++GO:0034971///histone H3-R17 methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051591///response to cAMP+++GO:0060350///endochondral bone morphogenesis+++GO:0071168///protein localization to chromatin+++GO:1902415///regulation of mRNA binding+++GO:2000171///negative regulation of dendrite development" 59036 59036 'Dact1' mRNA 41 45 35 0.61 0.64 0.54 0.57 0.37 0.55 0.596666667 0.496666667 44 28 42 40.33333333 38 0.863090843 -0.096761378 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0030877///beta-catenin destruction complex+++GO:0045202///synapse GO:0001085///RNA polymerase II transcription factor binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0042826///histone deacetylase binding+++GO:0051018///protein kinase A binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070097///delta-catenin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001702///gastrulation with mouth forming second+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0016055///Wnt signaling pathway+++GO:0021915///neural tube development+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0046329///negative regulation of JNK cascade+++GO:0048598///embryonic morphogenesis+++GO:0048619///embryonic hindgut morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0050808///synapse organization+++GO:0060070///canonical Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900107///regulation of nodal signaling pathway+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1904864///negative regulation of beta-catenin-TCF complex assembly+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 59038 59038 'Pxmp4' mRNA 822.62 816.27 864.43 29.28 28.28 32.16 24.85 25.03 26.4 29.90666667 25.42666667 809.81 809.29 836.06 834.44 818.3866667 0.763286588 -0.041450294 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 59040 59040 'Rhot1' mRNA 1611 1630 1653 20.95 20.91 22.71 14.55 14.46 15.48 21.52333333 14.83 1291 1254 1337 1631.333333 1294 2.68E-05 -0.347215216 04137///Mitophagy - animal+++04214///Apoptosis - fly GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005509///calcium ion binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0007005///mitochondrion organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0010821///regulation of mitochondrion organization+++GO:0019725///cellular homeostasis+++GO:0034640///establishment of mitochondrion localization by microtubule attachment+++GO:0046928///regulation of neurotransmitter secretion+++GO:0047497///mitochondrion transport along microtubule+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:1902513///regulation of organelle transport along microtubule 59041 59041 'Stk25' mRNA 2401.8 2356.91 2083.13 58.34 55.95 54.56 39.09 32.6 34.13 56.28333333 35.27333333 1816.06 1479.24 1521.96 2280.613333 1605.753333 1.99E-10 -0.517579729 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007163///establishment or maintenance of cell polarity+++GO:0016310///phosphorylation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0042542///response to hydrogen peroxide+++GO:0046777///protein autophosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0051645///Golgi localization+++GO:0051683///establishment of Golgi localization+++GO:0090168///Golgi reassembly 59042 59042 'Cope' mRNA 3998 4147 3949 237.01 243 248.39 271.93 270.24 253.47 242.8 265.2133333 5261 5097 4740 4031.333333 5032.666667 7.16E-07 0.307936091 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005198///structural molecule activity+++GO:0005515///protein binding "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0099612///protein localization to axon" 59043 59043 'Wsb2' mRNA 816.05 836.13 834.19 18.91 19.09 20.54 21.02 19.62 22.22 19.51333333 20.95333333 1043.24 950.1 1067.14 828.79 1020.16 0.003546767 0.286639914 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 59044 59044 'Rnf130' mRNA 790 857 632 24.04 25.54 20.21 31.67 34.47 34.9 23.26333333 33.68 1005 1069 1082 759.6666667 1052 1.27E-05 0.463928364 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0012501///programmed cell death+++GO:0016567///protein ubiquitination 59045 59045 'Stard3' mRNA 1005 1122 975 27.42 30.08 28.18 36.95 37.13 32.43 28.56 35.50333333 1563 1534 1328 1034 1475 3.71E-08 0.501904721 04979///Cholesterol metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044232///organelle membrane contact site GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0042803///protein homodimerization activity+++GO:0120020///intermembrane cholesterol transfer activity GO:0006701///progesterone biosynthetic process+++GO:0006869///lipid transport+++GO:0030301///cholesterol transport+++GO:0099044///vesicle tethering to endoplasmic reticulum+++GO:0120009///intermembrane lipid transfer 59046 59046 'Arpp19' mRNA 1260 1373 1545 44.99 45.35 58.55 57.88 67.18 59.61 49.63 61.55666667 1544 1600 1545 1392.666667 1563 0.191128097 0.150524741 GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0015459///potassium channel regulator activity+++GO:0019212///phosphatase inhibitor activity+++GO:0019888///protein phosphatase regulator activity+++GO:0051721///protein phosphatase 2A binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0045722///positive regulation of gluconeogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division 59047 59047 'Pnkp' mRNA 1053.66 977.83 869.55 21.13 19.78 19.78 21.84 26.49 26.21 20.23 24.84666667 1115.14 1254.83 1229.83 967.0133333 1199.933333 0.002305046 0.303582649 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0019005///SCF ubiquitin ligase complex+++GO:0035861///site of double-strand break "GO:0000166///nucleotide binding+++GO:0003690///double-stranded DNA binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046403///polynucleotide 3'-phosphatase activity+++GO:0046404///ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity+++GO:0051734///ATP-dependent polynucleotide kinase activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0010836///negative regulation of protein ADP-ribosylation+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0046939///nucleotide phosphorylation+++GO:0051103///DNA ligation involved in DNA repair+++GO:0051973///positive regulation of telomerase activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0098506///polynucleotide 3' dephosphorylation+++GO:1904355///positive regulation of telomere capping+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining" 59048 59048 'C1galt1c1' mRNA 1053 1032 1136 41.26 39.88 47.22 33.46 32.48 31.66 42.78666667 32.53333333 981 929 898 1073.666667 936 0.043943147 -0.213073263 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016263///glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity "GO:0006493///protein O-linked glycosylation+++GO:0016267///O-glycan processing, core 1+++GO:0030168///platelet activation+++GO:0036344///platelet morphogenesis+++GO:0051347///positive regulation of transferase activity" 59049 59049 'Slc22a17' mRNA 3853.32 3743.45 1614.92 89.43 85.5 40.25 20.04 20.35 23.32 71.72666667 21.23666667 978.77 979.9 1104.77 3070.563333 1021.146667 2.52E-05 -1.582178494 GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031301///integral component of organelle membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0015891///siderophore transport+++GO:0055072///iron ion homeostasis+++GO:0055085///transmembrane transport 59050 59050 'Nsa2' mRNA 547.36 595.52 523.72 11.29 12.09 11.46 15.2 14.72 16.17 11.61333333 15.36333333 848.09 802.22 873.22 555.5333333 841.1766667 5.82E-09 0.589096275 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor" GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 59052 59052 'Mettl9' mRNA 1660 1807 1064 54.76 59.6 37.92 36.18 44.19 42.95 50.76 41.10666667 1231 1476 1415 1510.333333 1374 0.64411333 -0.134980766 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0008150///biological_process+++GO:0032259///methylation 59053 59053 'Hgh1' mRNA 291 279 295 8.19 7.78 8.76 7.78 6.48 6.87 8.243333333 7.043333333 314 257 271 288.3333333 280.6666667 0.804977458 -0.053703984 GO:0005575///cellular_component GO:0003674///molecular_function 59054 59054 'Mrps30' mRNA 491 564 467 18.09 20.49 18.26 21.97 23.63 21.75 18.94666667 22.45 685 719 656 507.3333333 686.6666667 1.93E-04 0.427629233 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 59056 59056 'Evc' mRNA 449 496 445 5.81 6.31 6.22 3.81 3.15 4.11 6.113333333 3.69 348 288 358 463.3333333 331.3333333 3.30E-04 -0.495685846 04340///Hedgehog signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0098797///plasma membrane protein complex GO:0005515///protein binding GO:0003416///endochondral bone growth+++GO:0007224///smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051216///cartilage development 59057 59057 'Zfp24' mRNA 1820 1767 1909 16.42 15.82 18.58 13.84 12.62 12.61 16.94 13.02333333 1755 1564 1547 1832 1622 0.036901171 -0.19094617 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042552///myelination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 59058 59058 'Bhlhe22' mRNA 32 38 21 0.55 0.64 0.38 0.4 0.53 0.42 0.523333333 0.45 27 35 27 30.33333333 29.66666667 0.960346657 -0.032467403 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0021540///corpus callosum morphogenesis+++GO:0021796///cerebral cortex regionalization+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0021957///corticospinal tract morphogenesis+++GO:0021960///anterior commissure morphogenesis+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060040///retinal bipolar neuron differentiation+++GO:0060042///retina morphogenesis in camera-type eye" 59069 59069 'Tpm3' mRNA 3840.34 3942.54 4081.66 97.08 98.52 112.34 248.58 245.42 242.79 102.6466667 245.5966667 11137.91 10735.1 10604.4 3954.846667 10825.80333 2.92E-121 1.438868447 04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++05200///Pathways in cancer+++05216///Thyroid cancer+++05410///Hypertrophic cardiomyopathy+++05414///Dilated cardiomyopathy GO:0001725///stress fiber+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0015629///actin cytoskeleton+++GO:0030426///growth cone+++GO:0030863///cortical cytoskeleton+++GO:0032154///cleavage furrow+++GO:0043005///neuron projection GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization 59079 59079 'Erbin' mRNA 1307.07 1354.38 1347.32 10.52 10.78 11.53 11.99 11.16 10.68 10.94333333 11.27666667 1697.49 1540.62 1453.05 1336.256667 1563.72 0.01768839 0.213023745 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030056///hemidesmosome+++GO:0031594///neuromuscular junction+++GO:0031965///nuclear membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099572///postsynaptic specialization GO:0005102///signaling receptor binding+++GO:0005176///ErbB-2 class receptor binding+++GO:0005515///protein binding GO:0006605///protein targeting+++GO:0007165///signal transduction+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032495///response to muramyl dipeptide+++GO:0032496///response to lipopolysaccharide+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0070433///negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels 59083 59083 'Fetub' mRNA 10 12 6 0.37 0.53 0.25 2.41 3.12 2.62 0.383333333 2.716666667 73 90 77 9.333333333 80 1.53E-12 3.095938833 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004857///enzyme inhibitor activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 59090 59090 'Midn' mRNA 411 351 115 5.98 4.94 1.84 2.92 3.39 3.82 4.253333333 3.376666667 225 257 291 292.3333333 257.6666667 0.822332272 -0.169164873 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019900///kinase binding GO:0033132///negative regulation of glucokinase activity+++GO:0046676///negative regulation of insulin secretion 59091 59091 'Jph2' mRNA 11 8 2 0.14 0.1 0.03 0.05 0.03 0.05 0.09 0.043333333 4 2 3 7 3 0.364238278 -1.216726355 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane "GO:0001046///core promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001786///phosphatidylserine binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0070300///phosphatidic acid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0055024///regulation of cardiac muscle tissue development+++GO:0055074///calcium ion homeostasis+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity" 59092 59092 'Pcbp4' mRNA 4164 4135 3860 117.69 115.67 115.95 79.05 80.81 79.93 116.4366667 79.93 3226 3224 3163 4053 3204.333333 1.87E-09 -0.349791689 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding "GO:0010468///regulation of gene expression+++GO:0043488///regulation of mRNA stability+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0051252///regulation of RNA metabolic process+++GO:1902163///negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator" 59093 59093 'Pcbp3' mRNA 1087 1059 1047 28.56 27.67 29.35 7.91 7.92 9 28.52666667 8.276666667 349 338 382 1064.333333 356.3333333 3.57E-53 -1.590691592 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:1990829///C-rich single-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0051252///regulation of RNA metabolic process 59095 59095 'Fxyd6' mRNA 9253 9305 9259 281.01 277.25 298.56 197.56 201.39 192.73 285.6066667 197.2266667 7518 7496 7090 9272.333333 7368 2.61E-09 -0.34434904 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0017080///sodium channel regulator activity+++GO:0099106///ion channel regulator activity GO:0006811///ion transport+++GO:0043269///regulation of ion transport+++GO:2000649///regulation of sodium ion transmembrane transporter activity 59125 59125 'Nek7' mRNA 1995.04 2017.9 1326 24.97 24.8 17.65 14.81 16.43 17.87 22.47333333 16.37 1360.89 1478.86 1592.4 1779.646667 1477.383333 0.030716394 -0.270675203 04621///NOD-like receptor signaling pathway GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:1904355///positive regulation of telomere capping 59126 59126 'Nek6' mRNA 185 138 197 4.12 2.85 4.27 34.23 33.65 34.01 3.746666667 33.96333333 1746 1683 1697 173.3333333 1708.666667 9.63E-164 3.285583138 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0001222///transcription corepressor binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0046777///protein autophosphorylation+++GO:0051301///cell division 59287 59287 'Ncstn' mRNA 3564.71 3779.67 3446.06 68.89 71.88 70.64 81.41 78.49 72.71 70.47 77.53666667 4850.26 4567.55 4189.04 3596.813333 4535.616667 9.45E-07 0.323072498 04330///Notch signaling pathway+++05010///Alzheimer disease GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0045202///synapse+++GO:0070765///gamma-secretase complex+++GO:0097060///synaptic membrane+++GO:0099056///integral component of presynaptic membrane "GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0030674///protein binding, bridging+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0051117///ATPase binding+++GO:0070851///growth factor receptor binding" GO:0002262///myeloid cell homeostasis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007212///dopamine receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007611///learning or memory+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0021549///cerebellum development+++GO:0022010///central nervous system myelination+++GO:0030534///adult behavior+++GO:0034205///amyloid-beta formation+++GO:0042098///T cell proliferation+++GO:0042982///amyloid precursor protein metabolic process+++GO:0042983///amyloid precursor protein biosynthetic process+++GO:0042986///positive regulation of amyloid precursor protein biosynthetic process+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0050435///amyloid-beta metabolic process+++GO:0050673///epithelial cell proliferation+++GO:0051402///neuron apoptotic process+++GO:0070997///neuron death+++GO:0071277///cellular response to calcium ion+++GO:1900271///regulation of long-term synaptic potentiation+++GO:1990926///short-term synaptic potentiation 59288 59288 'Dctn5' mRNA 1733 1875 1787 66.63 71.1 72.89 86.05 85.13 82.48 70.20666667 84.55333333 2571 2482 2384 1798.333333 2479 3.44E-10 0.450731949 04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0031965///nuclear membrane" GO:0003674///molecular_function GO:0003281///ventricular septum development+++GO:0035904///aorta development+++GO:0060976///coronary vasculature development 59289 59289 'Ackr2' mRNA 5 5 5 0.09 0.09 0.1 0.08 0.07 0.22 0.093333333 0.123333333 5 4 13 5 7.333333333 0.680478367 0.541648841 GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity+++GO:0019957///C-C chemokine binding GO:0006897///endocytosis+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 59290 59290 'Gpa33' mRNA 1 5 2 0.07 0.12 0.07 0.1 0.04 0.08 0.086666667 0.073333333 5 2 4 2.666666667 3.666666667 0.814775512 0.45218654 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 59308 59308 'Emcn' mRNA 359 373 360 14.69 15.02 15.55 31.41 30.84 29.65 15.08666667 30.63333333 885 848 804 364 845.6666667 2.40E-29 1.20400081 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0001525///angiogenesis+++GO:0030155///regulation of cell adhesion+++GO:0061484///hematopoietic stem cell homeostasis+++GO:0098609///cell-cell adhesion 59310 59310 'Myl10' mRNA 0 0 2 0 0 0.09 0 0.12 0 0.03 0.04 0 1 0 0.666666667 0.333333333 0.863090843 -0.975276534 04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection GO:0005739///mitochondrion GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process 594844 594844 'Tceal3' mRNA 853.39 901.43 845.19 47.33 49.43 49.89 20 19.33 20.11 48.88333333 19.81333333 414.31 390.82 403.82 866.67 402.9833333 2.00E-27 -1.118372831 GO:0005634///nucleus GO:0050699///WW domain binding 595136 595136 'Ndufs5' mRNA 2316 2373 2372 381.25 390.54 414.58 321.58 377.96 335.14 395.4566667 344.8933333 2222 2534 2228 2353.666667 2328 0.816954141 -0.02744628 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 60315 60315 'Myg1' mRNA 956 922 894 38.64 36.89 38.47 32.92 33.72 31.33 38 32.65666667 930 938 858 924 908.6666667 0.782061644 -0.035599254 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003674///molecular_function+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity GO:0035641///locomotory exploration behavior+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 60321 60321 'Wbp11' mRNA 1552 1582 1312 32.25 32.35 28.97 27.6 25.07 25.68 31.19 26.11666667 1530 1359 1379 1482 1422.666667 0.49766456 -0.06844255 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0050699///WW domain binding "GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0050790///regulation of catalytic activity" 60322 60322 'Chst7' mRNA 90 116 127 2.31 2.93 3.46 5.02 5.33 4.84 2.9 5.063333333 225 233 210 111 222.6666667 2.70E-06 0.988790622 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0008459///chondroitin 6-sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0030206///chondroitin sulfate biosynthetic process 60344 60344 'Fign' mRNA 963 940 724 5.17 4.95 4.12 1.19 1.25 1.32 4.746666667 1.253333333 255 262 276 875.6666667 264.3333333 2.86E-45 -1.734125134 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016887///ATPase activity GO:0007049///cell cycle+++GO:0007626///locomotory behavior+++GO:0031122///cytoplasmic microtubule organization+++GO:0051013///microtubule severing+++GO:0051301///cell division 60345 60345 'Nrip2' mRNA 341.06 336.36 346.24 10.57 10.35 11.6 3.39 4.03 3.7 10.84 3.706666667 125.84 143.66 131.36 341.22 133.62 2.03E-16 -1.370458 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0007219///Notch signaling pathway 60361 60361 'Ms4a4b' mRNA 9 5 3 0.44 0.24 0.15 4.2 4.57 4.33 0.276666667 4.366666667 99.72 105.89 99.4 5.666666667 101.67 1.68E-18 4.149316438 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft 60363 60363 'Cldn15' mRNA 9 3 8 0.28 0.09 0.26 0.38 0.44 0.25 0.21 0.356666667 14 16 9 6.666666667 13 0.311114632 0.944115523 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction GO:0005198///structural molecule activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 60364 60364 'Donson' mRNA 446 514 432 10.76 12.21 11.06 4.87 6.83 6.72 11.34333333 6.14 232 318 310 464 286.6666667 8.15E-06 -0.701647184 GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0030894///replisome GO:0003674///molecular_function GO:0000077///DNA damage checkpoint+++GO:0006260///DNA replication+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007275///multicellular organism development+++GO:0033260///nuclear DNA replication+++GO:0048478///replication fork protection 60365 60365 'Rbm8a' mRNA 1795 1693 1724 38.11 35.38 38.83 40.14 40.64 40.01 37.44 40.26333333 2175 2150 2099 1737.333333 2141.333333 1.16E-04 0.289176342 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0030425///dendrite+++GO:0035145///exon-exon junction complex+++GO:0043025///neuronal cell body+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0008380///RNA splicing+++GO:0051028///mRNA transport" 60367 60367 'Il1rapl2' mRNA 6 2 5 0.06 0.02 0.05 0 0 0 0.043333333 0 0 0 0 4.333333333 0 0.032071163 -4.579107345 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse "GO:0003953///NAD+ nucleosidase activity+++GO:0004910///interleukin-1, type II, blocking receptor activity+++GO:0016787///hydrolase activity+++GO:0050135///NAD(P)+ nucleosidase activity+++GO:0061809///NAD+ nucleotidase, cyclic ADP-ribose generating" GO:0007165///signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:1905606///regulation of presynapse assembly 60406 60406 'Sap30' mRNA 261 221 46 13.59 11.36 2.54 4.17 9.07 11.12 9.163333333 8.12 92 195 237 176 174.6666667 0.997389888 0.012977551 05169///Epstein-Barr virus infection GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016580///Sin3 complex GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035914///skeletal muscle cell differentiation+++GO:0052472///modulation by host of symbiont transcription" 60409 60409 'Trappc4' mRNA 1558 1550 1524 83.81 82.69 88.28 80.15 82.28 80.81 84.92666667 81.08 1674 1698 1667 1544 1679.666667 0.199434629 0.109666243 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030008///TRAPP complex+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane "GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0008283///cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0016358///dendrite development 60411 60411 'Cenpk' mRNA 9.55 13.12 11.3 0.53 0.8 0.68 4.75 3.66 5.33 0.67 4.58 88.7 64 95.88 11.32333333 82.86 6.79E-12 2.891091843 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000941///condensed nuclear chromosome inner kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0005515///protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051382///kinetochore assembly 60425 60425 'Doc2g' mRNA 76 56 57 3.25 2.36 2.59 1.08 2.02 1.62 2.733333333 1.573333333 29 53 42 63 41.33333333 0.125754907 -0.61377274 GO:0016020///membrane+++GO:0045202///synapse+++GO:0098793///presynapse GO:0046872///metal ion binding GO:0061669///spontaneous neurotransmitter secretion 60440 60440 'Iigp1' mRNA 1012 1096 939 18.16 19.33 17.88 29.97 31.37 29.31 18.45666667 30.21666667 1923 1965 1821 1015.666667 1903 3.41E-30 0.896316128 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0020005///symbiont-containing vacuole membrane+++GO:0031965///nuclear membrane+++GO:0032580///Golgi cisterna membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0042802///identical protein binding GO:0002376///immune system process+++GO:0006952///defense response+++GO:0009617///response to bacterium+++GO:0010506///regulation of autophagy+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035458///cellular response to interferon-beta+++GO:0042832///defense response to protozoan+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium 60441 60441 'Mrpl38' mRNA 1000 975 892 42.28 40.68 40.01 35.16 34.72 35.4 40.99 35.09333333 955 920 930 955.6666667 935 0.72821651 -0.042071316 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function GO:0008150///biological_process 60455 60455 'Pgap6' mRNA 390 420 415 6.13 6.49 6.92 8.9 8.29 8.37 6.513333333 8.52 652 593 594 408.3333333 613 1.27E-06 0.572775186 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0004623///phospholipase A2 activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity" GO:0006486///protein glycosylation+++GO:0008150///biological_process+++GO:0035269///protein O-linked mannosylation 60504 60504 'Il21r' mRNA 88 73 43 2.01 1.55 1 15.24 12.72 12.23 1.52 13.39666667 783 632 634 68 683 2.87E-75 3.321529203 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++05321///Inflammatory bowel disease GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity GO:0019221///cytokine-mediated signaling pathway 60505 60505 'Il21' mRNA 0 2 0 0 0.03 0 0 0.02 0 0.01 0.006666667 0 1 0 0.666666667 0.333333333 0.863090843 -0.864760308 04060///Cytokine-cytokine receptor interaction+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++05321///Inflammatory bowel disease GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005134///interleukin-2 receptor binding GO:0001783///B cell apoptotic process+++GO:0001819///positive regulation of cytokine production+++GO:0002314///germinal center B cell differentiation+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0008284///positive regulation of cell proliferation+++GO:0030890///positive regulation of B cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0042102///positive regulation of T cell proliferation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045579///positive regulation of B cell differentiation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0048469///cell maturation+++GO:0061470///T follicular helper cell differentiation+++GO:0098586///cellular response to virus 60507 60507 'Qtrt1' mRNA 226 246 230 10.6 11.39 11.24 11.57 11.9 9.96 11.07666667 11.14333333 281 287 241 234 269.6666667 0.303732081 0.193081618 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex "GO:0005515///protein binding+++GO:0008479///queuine tRNA-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity" GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0101030///tRNA-guanine transglycosylation 60510 60510 'Syt9' mRNA 61 87 62 0.94 1.25 0.99 0.92 1.01 0.81 1.06 0.913333333 69 76 63 70 69.33333333 0.961538013 -0.020961789 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031045///dense core granule+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0070382///exocytic vesicle+++GO:0098686///hippocampal mossy fiber to CA3 synapse "GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019905///syntaxin binding+++GO:0030276///clathrin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0050796///regulation of insulin secretion+++GO:0071277///cellular response to calcium ion+++GO:0099502///calcium-dependent activation of synaptic vesicle fusion 60525 60525 'Acss2' mRNA 3977 4154 4167 77.43 79.6 86.06 18.84 17.16 16.69 81.03 17.56333333 1113 990 955 4099.333333 1019.333333 4.58E-158 -2.022032646 00010///Glycolysis / Gluconeogenesis+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003987///acetate-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0050218///propionate-CoA ligase activity GO:0006085///acetyl-CoA biosynthetic process+++GO:0008610///lipid biosynthetic process+++GO:0019413///acetate biosynthetic process+++GO:0019542///propionate biosynthetic process 60527 60527 'Fads3' mRNA 271 222 207 4.53 3.65 3.67 5.2 5.22 5.58 3.95 5.333333333 358 351 372 233.3333333 360.3333333 7.32E-05 0.617557604 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0006665///sphingolipid metabolic process 60530 60530 'Fignl1' mRNA 7 15 16 0.13 0.27 0.32 2.73 3.12 3.49 0.24 3.113333333 169 182 207 12.66666667 186 1.54E-30 3.863413666 GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0001649///osteoblast differentiation+++GO:0007140///male meiotic nuclear division+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0031122///cytoplasmic microtubule organization+++GO:0033687///osteoblast proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0046034///ATP metabolic process+++GO:0051013///microtubule severing+++GO:0051726///regulation of cell cycle+++GO:0071479///cellular response to ionizing radiation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 60532 60532 'Wtap' mRNA 1895 1646 1398 44.62 35.58 36.89 39.84 36.74 36.11 39.03 37.56333333 1899 1801 1729 1646.333333 1809.666667 0.214006077 0.128359856 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0080009///mRNA methylation" 60533 60533 'Cd274' mRNA 113 119.01 113.09 1.62 1.6 1.71 4.89 3.71 4.57 1.643333333 4.39 379 281.81 345 115.0333333 335.27 9.92E-18 1.528751611 04514///Cell adhesion molecules+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome GO:0005515///protein binding "GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002845///positive regulation of tolerance induction to tumor cell+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0031295///T cell costimulation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0034097///response to cytokine+++GO:0042102///positive regulation of T cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901998///toxin transport+++GO:1903556///negative regulation of tumor necrosis factor superfamily cytokine production+++GO:1905404///positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2001186///negative regulation of CD8-positive, alpha-beta T cell activation" 60534 60534 'Fancg' mRNA 285 272 272 5.65 5.26 5.8 4.87 4.88 5.6 5.57 5.116666667 280 272 310 276.3333333 287.3333333 0.842342284 0.044455021 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043240///Fanconi anaemia nuclear complex GO:0001541///ovarian follicle development+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007005///mitochondrion organization+++GO:0007286///spermatid development+++GO:0009314///response to radiation+++GO:0036297///interstrand cross-link repair 60594 60594 'Capn12' mRNA 37.42 39.34 43.54 0.73 0.76 0.9 0.33 0.51 0.43 0.796666667 0.423333333 19.33 29.43 24.38 40.1 24.38 0.124595487 -0.736827289 GO:0005737///cytoplasm GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 60595 60595 'Actn4' mRNA 19489.58 20811.66 19625.46 271.81 285.46 290.5 159.01 160.81 152.32 282.59 157.38 13110.67 12949.57 12160.62 19975.56667 12740.28667 4.39E-35 -0.660873656 04510///Focal adhesion+++04520///Adherens junction+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05146///Amoebiasis+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0001725///stress fiber+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0016604///nuclear body+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030863///cortical cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0031143///pseudopodium+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001882///nucleoside binding+++GO:0003713///transcription coactivator activity+++GO:0003779///actin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0042803///protein homodimerization activity+++GO:0042974///retinoic acid receptor binding+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051015///actin filament binding "GO:0001666///response to hypoxia+++GO:0015031///protein transport+++GO:0030036///actin cytoskeleton organization+++GO:0030050///vesicle transport along actin filament+++GO:0030335///positive regulation of cell migration+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048549///positive regulation of pinocytosis+++GO:0051017///actin filament bundle assembly+++GO:0051271///negative regulation of cellular component movement+++GO:0051272///positive regulation of cellular component movement+++GO:0055001///muscle cell development+++GO:0070830///bicellular tight junction assembly+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902396///protein localization to bicellular tight junction+++GO:1903506///regulation of nucleic acid-templated transcription" 60596 60596 'Gucy1a1' mRNA 147 148 110 1.66 1.65 1.32 1.18 1.06 1.08 1.543333333 1.106666667 120 105 106 135 110.3333333 0.244751034 -0.298635315 00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04540///Gap junction+++04611///Platelet activation+++04713///Circadian entrainment+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++04924///Renin secretion+++04970///Salivary secretion "GO:0005737///cytoplasm+++GO:0008074///guanylate cyclase complex, soluble+++GO:0032991///protein-containing complex+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse" GO:0000166///nucleotide binding+++GO:0004016///adenylate cyclase activity+++GO:0004383///guanylate cyclase activity+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0020037///heme binding+++GO:0043167///ion binding+++GO:0044877///protein-containing complex binding+++GO:0047805///cytidylate cyclase activity "GO:0006182///cGMP biosynthetic process+++GO:0008217///regulation of blood pressure+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0010750///positive regulation of nitric oxide mediated signal transduction+++GO:0035556///intracellular signal transduction+++GO:0060087///relaxation of vascular smooth muscle+++GO:0098925///retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission" 60597 60597 'Mapk8ip2' mRNA 228 237 228 3.5 3.58 3.71 0.53 0.67 0.47 3.596666667 0.556666667 40 49 34 231 41 1.13E-26 -2.505397964 04010///MAPK signaling pathway GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0044877///protein-containing complex binding "GO:0000165///MAPK cascade+++GO:0001662///behavioral fear response+++GO:0007254///JNK cascade+++GO:0007617///mating behavior+++GO:0010469///regulation of signaling receptor activity+++GO:0016310///phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0035176///social behavior+++GO:0046328///regulation of JNK cascade+++GO:0046958///nonassociative learning+++GO:0048813///dendrite morphogenesis+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:2000310///regulation of NMDA receptor activity+++GO:2000311///regulation of AMPA receptor activity+++GO:2001234///negative regulation of apoptotic signaling pathway" 60599 60599 'Trp53inp1' mRNA 2000 2164 2233 19.71 20.97 23.35 15.71 15.16 15.61 21.34333333 15.49333333 1835 1731 1767 2132.333333 1777.666667 0.001068162 -0.276968041 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0031410///cytoplasmic vesicle GO:0016209///antioxidant activity "GO:0000045///autophagosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0009408///response to heat+++GO:0010506///regulation of autophagy+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030336///negative regulation of cell migration+++GO:0034644///cellular response to UV+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048102///autophagic cell death+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0071361///cellular response to ethanol+++GO:0071447///cellular response to hydroperoxide+++GO:0072703///cellular response to methyl methanesulfonate+++GO:0098869///cellular oxidant detoxification+++GO:1904761///negative regulation of myofibroblast differentiation+++GO:2001235///positive regulation of apoptotic signaling pathway" 60611 60611 'Foxj2' mRNA 353 318 303 3.76 3.33 3.42 3.5 2.9 3.46 3.503333333 3.286666667 378 306 362 324.6666667 348.6666667 0.6267523 0.090893254 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051321///meiotic cell cycle+++GO:0110059///negative regulation of blood vessel endothelial cell differentiation+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation" 60613 60613 'Kcnq4' mRNA 167 172 163 2.52 2.32 2.55 1.47 1.3 1.08 2.463333333 1.283333333 111 94 82 167.3333333 95.66666667 2.42E-04 -0.819693066 04725///Cholinergic synapse GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005516///calmodulin binding "GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007605///sensory perception of sound+++GO:0032227///negative regulation of synaptic transmission, dopaminergic+++GO:0034765///regulation of ion transmembrane transport+++GO:0042472///inner ear morphogenesis+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport" 606496 606496 'Gsk3a' mRNA 217.96 212.42 103.15 6.08 5.84 3.05 3.92 4.67 3.77 4.99 4.12 161.4 188.48 151.33 177.8433333 167.07 0.805321344 -0.086115058 04062///Chemokine signaling pathway+++04728///Dopaminergic synapse+++04932///Non-alcoholic fatty liver disease+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0030424///axon GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0050321///tau-protein kinase activity "GO:0003073///regulation of systemic arterial blood pressure+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007568///aging+++GO:0008286///insulin receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010975///regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032007///negative regulation of TOR signaling+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0036016///cellular response to interleukin-3+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0044027///hypermethylation of CpG island+++GO:0045823///positive regulation of heart contraction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0071285///cellular response to lithium ion+++GO:0071407///cellular response to organic cyclic compound+++GO:0071879///positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0106071///positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1902004///positive regulation of amyloid-beta formation+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:1904227///negative regulation of glycogen synthase activity, transferring glucose-1-phosphate+++GO:2000171///negative regulation of dendrite development+++GO:2000467///positive regulation of glycogen (starch) synthase activity" 613262 613262 'BC029722' mRNA 1135.53 1113.03 899.58 47.62 46.05 40.02 37.98 44.62 40.69 44.56333333 41.09666667 1040.1 1192.15 1077.84 1049.38 1103.363333 0.612042494 0.066105616 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 613264 613264 '1810020O05Rik' mRNA 241.1 188.59 179.63 1.91 1.48 1.52 0.63 0.57 0.66 1.636666667 0.62 90.55 80.35 92.52 203.1066667 87.80666667 1.61E-08 -1.22441827 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 619287 619287 'Rtl4' mRNA 5 12 12 0.08 0.18 0.19 0.03 0 0.04 0.15 0.023333333 2 0 3 9.666666667 1.666666667 0.043512558 -2.559253499 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0042415///norepinephrine metabolic process+++GO:0050890///cognition 619289 619289 'Rfx8' mRNA 4 18 6 0.11 0.5 0.18 0.2 0.36 0.33 0.263333333 0.296666667 8 14 13 9.333333333 11.66666667 0.765715423 0.329410057 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 619290 619290 'A230072I06Rik' mRNA 1 0 2 0.01 0 0.03 0 0 0 0.013333333 0 0 0 0 1 0 0.59486514 -2.49405383 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 619297 619297 'Ccdc194' mRNA 86 83 106 2.69 2.56 3.52 1.14 1.7 1.94 2.923333333 1.593333333 42 61 69 91.66666667 57.33333333 0.036663579 -0.691647479 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 619301 619301 'Tmem253' mRNA 46.89 41.71 52.56 2.06 1.57 2.22 0.49 0.36 0.32 1.95 0.39 16 10 9.24 47.05333333 11.74666667 4.99E-05 -2.009982327 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 619309 619309 'Muc3a' mRNA 35 36 37 0.17 0.17 0.19 0.11 0.09 0.14 0.176666667 0.113333333 16 17 10 36 14.33333333 0.009775567 -1.342126157 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 619310 619310 'Zfp872' mRNA 39 39 25 0.72 0.71 0.49 0.47 0.28 0.42 0.64 0.39 29 17 25 34.33333333 23.66666667 0.312049187 -0.543909478 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 619326 619326 '9130409I23Rik' mRNA 0 0 3 0 0 0.1 0 0 0 0.033333333 0 0 0 0 1 0 0.625198426 -2.527571966 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity+++GO:0042284///sphingolipid delta-4 desaturase activity+++GO:0050251///retinol isomerase activity GO:0006629///lipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0043217///myelin maintenance+++GO:0046513///ceramide biosynthetic process 619331 619331 'Zfp551' mRNA 152 234 212 2.42 4.09 4 1.66 1.17 1.9 3.503333333 1.576666667 116 88 121 199.3333333 108.3333333 1.60E-04 -0.894769461 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 619441 619441 'Tnfsfm13' mRNA 79.66 84.76 59.85 2.01 2.11 1.6 1.69 2.07 2.72 1.906666667 2.16 77.05 92.35 119.89 74.75666667 96.43 0.256867881 0.371757766 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0048018///receptor ligand activity GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0048298///positive regulation of isotype switching to IgA isotypes 619547 619547 'Rpl34-ps1' mRNA 1219.25 1215.26 1331.5 289.4 290.52 335.85 191.42 175.03 202.73 305.2566667 189.7266667 911.96 806.98 926.85 1255.336667 881.93 1.77E-07 -0.525990931 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation 619548 619548 'Defb42' mRNA 1 0 0 0.12 0 0 0.32 0.11 0 0.04 0.143333333 3 1 0 0.333333333 1.333333333 0.615791003 1.868085929 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0006952///defense response+++GO:0008150///biological_process+++GO:0042742///defense response to bacterium 619597 619597 'Gal3st2c' mRNA 17.94 19 19.95 0.24 0.25 0.28 0.04 0.08 0.06 0.256666667 0.06 3.28 6.48 5.43 18.96333333 5.063333333 0.012242108 -1.983722 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001733///galactosylceramide sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0050694///galactose 3-O-sulfotransferase activity GO:0009101///glycoprotein biosynthetic process+++GO:0009247///glycolipid biosynthetic process 619605 619605 'Zcchc17' mRNA 1122 1013 1144 34.18 30.87 37.02 31.87 37.42 33.48 34.02333333 34.25666667 1231 1370 1227 1093 1276 0.054764886 0.209799947 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0022625///cytosolic large ribosomal subunit GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0043489///RNA stabilization 619665 619665 'Klf14' mRNA 2 2 1 0.04 0.04 0.02 0.08 0.07 0.03 0.033333333 0.06 5 4 2 1.666666667 3.666666667 0.535151229 1.132123906 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902070///positive regulation of sphingolipid mediated signaling pathway 619788 619788 'Vmn2r117' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 619883 619883 'Gm6109' mRNA 8.01 4.18 7.03 1.51 0.79 1.4 0.5 1.11 0.69 1.233333333 0.766666667 3.01 6.47 4.02 6.406666667 4.5 0.684650159 -0.560101733 03010///Ribosome+++05171///Coronavirus disease - COVID-19 619941 619941 'Gm13770' mRNA 5 1 4 0.07 0.01 0.06 0.07 0.09 0.06 0.046666667 0.073333333 6 7 5 3.333333333 6 0.5611663 0.828487595 620078 620078 'C130026I21Rik' mRNA 4.61 9.28 12.88 0.13 0.22 0.4 1.21 1.31 1.55 0.25 1.356666667 47.94 56.84 61.95 8.923333333 55.57666667 1.69E-07 2.696634674 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 620235 620235 'Siglec15' mRNA 40 35 37 0.98 0.85 0.96 0.79 0.7 0.46 0.93 0.65 37 32 21 37.33333333 30 0.535078516 -0.329933231 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding GO:0032956///regulation of actin cytoskeleton organization+++GO:0045124///regulation of bone resorption+++GO:2001204///regulation of osteoclast development 620246 620246 'Gpr52' mRNA 1 8 7 0.01 0.11 0.11 0.1 0.09 0.04 0.076666667 0.076666667 8 7 3 5.333333333 6 0.917329266 0.148875148 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008020///G protein-coupled photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007602///phototransduction+++GO:0007626///locomotory behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0009584///detection of visible light+++GO:0042493///response to drug+++GO:0071482///cellular response to light stimulus 620253 620253 'Dcpp3' mRNA 3 0 3.6 0.37 0 0.48 0.11 0.65 0.34 0.283333333 0.366666667 1 5.84 3 2.2 3.28 0.800528149 0.565196911 GO:0005615///extracellular space GO:0003674///molecular_function GO:0008150///biological_process 620292 620292 'Cntnap5c' mRNA 3.31 4.87 4.03 0.02 0.02 0.02 0.01 0.02 0.02 0.02 0.016666667 3.01 5.15 4.86 4.07 4.34 0.94376433 0.11519936 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007155///cell adhesion 620419 620419 'Zfp963' mRNA 232 261 248 5.69 6.3 6.45 4.94 3.58 4.4 6.146666667 4.306666667 232 164 200 247 198.6666667 0.093095679 -0.328958343 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 620480 620480 'Gm6155' mRNA 3.95 1.14 1.14 0.45 0.13 0.14 0 0 0 0.24 0 0 0 0 2.076666667 0 0.334169217 -3.181769893 620499 620499 'Gm6158' mRNA 0 0 33.68 0 0 1.29 1.59 0.84 1.31 0.43 1.246666667 50.59 26.17 40.47 11.22666667 39.07666667 0.569718416 1.71676932 620592 620592 'Tmem28' mRNA 22 17 20 0.25 0.19 0.24 0.05 0 0.03 0.226666667 0.026666667 5 0 3 19.66666667 2.666666667 0.001373415 -2.904941732 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0015275///stretch-activated, cation-selective, calcium channel activity" GO:0098703///calcium ion import across plasma membrane 620631 620631 'Ttc30a2' mRNA 8.17 3.56 1.4 0.23 0.1 0.04 0.48 0.16 0.27 0.123333333 0.303333333 19.45 6.18 10.77 4.376666667 12.13333333 0.157032473 1.53913344 GO:0005879///axonemal microtubule+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0120170///intraciliary transport particle B binding GO:0030030///cell projection organization+++GO:0042073///intraciliary transport 620695 620695 'Gm13889' mRNA 12 5 8 0.56 0.23 0.4 0.33 0.34 0.51 0.396666667 0.393333333 8 8 12 8.333333333 9.333333333 0.886537466 0.151122528 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 620709 620709 'Lcn6' mRNA 0 2 0 0 0.17 0 0 0 0 0.056666667 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0036094///small molecule binding GO:0008150///biological_process 620779 620779 'Gm12695' mRNA 2 3 0 0.06 0.08 0 0 0 0 0.046666667 0 0 0 0 1.666666667 0 0.385064596 -3.153564358 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 620913 620913 'Gm12185' mRNA 6.93 5 21.01 0.07 0.05 0.22 0.25 0.17 0.27 0.113333333 0.23 28.62 19.13 29.48 10.98 25.74333333 0.098252302 1.205159904 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 621080 621080 'AI429214' mRNA 244 240 251 7.11 6.89 7.76 4.71 4.93 5.11 7.253333333 4.916666667 186 190 195 245 190.3333333 0.036629115 -0.377134378 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 621239 621239 'Nhlrc4' mRNA 0 1 1 0 0.03 0.03 0.05 0 0.02 0.02 0.023333333 2 0 1 0.666666667 1 0.875025628 0.546587239 GO:0005575///cellular_component GO:0061630///ubiquitin protein ligase activity GO:0070936///protein K48-linked ubiquitination 621580 621580 'Gm21953' mRNA 4.7 8.1 5.65 1.12 1.94 1.43 0.69 0.86 0.49 1.496666667 0.68 3.29 3.94 2.22 6.15 3.15 0.439248075 -1.094654637 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor+++04062///Chemokine signaling pathway 621603 621603 'Aldh3b2' mRNA 33.2 44.38 31.63 0.87 1.14 0.88 0.8 0.71 0.64 0.963333333 0.716666667 35.12 30.46 27.23 36.40333333 30.93666667 0.664230236 -0.239986294 00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450 GO:0005737///cytoplasm+++GO:0005811///lipid droplet "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0006068///ethanol catabolic process+++GO:0006081///cellular aldehyde metabolic process 621628 621628 'Cldn20' mRNA 1 1 3 0.11 0.11 0.35 0.78 0.1 0.3 0.19 0.393333333 8 1 3 1.666666667 4 0.514990219 1.215017435 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0070160///tight junction GO:0003674///molecular_function 621697 621697 'Rpl32l' mRNA 27 29 29.01 3.51 3.76 4 4.45 3.28 4.61 3.756666667 4.113333333 39.01 28 39 28.33666667 35.33666667 0.575937352 0.303790745 03010///Ribosome+++05171///Coronavirus disease - COVID-19 621823 621823 'Psme2b' mRNA 40.02 42.94 21.83 2.36 2.51 1.37 8.19 8.9 7.85 2.08 8.313333333 158.95 168.42 147.39 34.93 158.2533333 9.70E-15 2.19677012 03050///Proteasome+++04612///Antigen processing and presentation GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008537///proteasome activator complex GO:0042802///identical protein binding GO:0008150///biological_process+++GO:0010950///positive regulation of endopeptidase activity+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 621893 621893 'H2ac21' mRNA 0 1 1 0 0.19 0.2 0.17 0.17 0.17 0.13 0.17 1 1 1 0.666666667 1 0.863090843 0.563154296 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 621976 621976 'Tmem170b' mRNA 1506 1627 1802 10.82 11.48 13.74 6.52 5.72 6.91 12.01333333 6.383333333 1047 895 1072 1645 1004.666667 5.42E-12 -0.728392766 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0090090///negative regulation of canonical Wnt signaling pathway 622019 622019 'Gm11780' mRNA 2 1 3 0.07 0.03 0.11 0 0 0 0.07 0 0 0 0 2 0 0.241331064 -3.474413743 622098 622098 'Gm6285' mRNA 0 0 2.02 0 0 0.29 0.42 0 0 0.096666667 0.14 3.52 0 0 0.673333333 1.173333333 0.905819236 0.481524111 622127 622127 'Cyp3a57' mRNA 1 4 0 0.03 0.11 0 0 0.08 0 0.046666667 0.026666667 0 3 0 1.666666667 1 0.847272903 -0.689415952 GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005496///steroid binding+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0050649///testosterone 6-beta-hydroxylase activity+++GO:0070330///aromatase activity+++GO:0070576///vitamin D 24-hydroxylase activity+++GO:0101020///estrogen 16-alpha-hydroxylase activity+++GO:0101021///estrogen 2-hydroxylase activity" GO:0008202///steroid metabolic process+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0070989///oxidative demethylation 622306 622306 'Gm6309' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 622320 622320 'Kctd21' mRNA 249 276 272 4.6 5.02 5.33 3.58 3.54 3.2 4.983333333 3.44 223 216 193 265.6666667 210.6666667 0.049928282 -0.347919599 GO:0005575///cellular_component GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0097602///cullin family protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0040008///regulation of growth+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0051260///protein homooligomerization 622404 622404 'Ccdc107' mRNA 1192 1254 1248 99.2 103.42 110.21 66.08 73.45 66.93 104.2766667 68.82 909 984 889 1231.333333 927.3333333 8.82E-06 -0.421265755 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 622434 622434 'Arhgef26' mRNA 935 975 888 9.88 10.17 9.82 7.86 6.38 6.97 9.956666667 7.07 873 682 734 932.6666667 763 0.004942771 -0.302511785 05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection GO:0005575///cellular_component GO:0005085///guanyl-nucleotide exchange factor activity GO:0001886///endothelial cell morphogenesis+++GO:0090630///activation of GTPase activity+++GO:0097178///ruffle assembly 622480 622480 'Spocd1' mRNA 0 2 0 0 0.03 0 0.01 0 0.03 0.01 0.013333333 1 0 2 0.666666667 1 0.870840676 0.605802875 GO:0005634///nucleus+++GO:0005694///chromosome GO:0005515///protein binding "GO:0006306///DNA methylation+++GO:0006351///transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0010529///negative regulation of transposition+++GO:0010923///negative regulation of phosphatase activity+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:1990511///piRNA biosynthetic process" 622486 622486 'Smok3c' mRNA 3.34 7.42 5.06 0.09 0.18 0.13 0.2 0.08 0.12 0.133333333 0.133333333 9.35 3.68 5.5 5.273333333 6.176666667 0.906281965 0.162036469 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction 622554 622554 'Majin' mRNA 31 32 17 1.22 1.15 0.75 0.22 0.37 0.27 1.04 0.286666667 6 11 8 26.66666667 8.333333333 0.00993789 -1.674621628 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane" GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0007129///synapsis+++GO:0045141///meiotic telomere clustering+++GO:0051321///meiotic cell cycle+++GO:0070197///meiotic attachment of telomere to nuclear envelope 622645 622645 'Tmem200c' mRNA 82 80 11 1.4 1.34 0.2 0.18 0.12 0.31 0.98 0.203333333 12 8 20 57.66666667 13.33333333 9.28E-04 -2.095466471 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 622665 622665 'Ccdc17' mRNA 250 245 244 7.1 6.86 7.36 4 4.58 3.6 7.106666667 4.06 162 181 141 246.3333333 161.3333333 8.01E-04 -0.622134218 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 622675 622675 'Zfp827' mRNA 1138 1143 912 6.02 6.15 5.07 2.53 2.03 2.61 5.746666667 2.39 543 411 527 1064.333333 493.6666667 2.88E-22 -1.117588438 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 622699 622699 'Gm12569' mRNA 20.39 11.67 14.21 0.18 0.1 0.13 0.1 0.06 0.07 0.136666667 0.076666667 12.54 7.94 8.84 15.42333333 9.773333333 0.36692217 -0.753021682 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 622976 622976 'Gm6377' mRNA 10 1 3 0.2 0.02 0.06 3.82 3.37 2.71 0.093333333 3.3 223 192 153 4.666666667 189.3333333 7.41E-30 5.330661334 GO:0005575///cellular_component GO:0003674///molecular_function GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0035751///regulation of lysosomal lumen pH 623078 623078 'Gm8108' mRNA 5.76 3 3 0.17 0.09 0.09 0.18 0.23 0.21 0.116666667 0.206666667 6.96 8.77 7.97 3.92 7.9 0.459731585 0.926674137 623121 623121 'Ifi213' mRNA 60.77 33 43.01 1.23 0.68 1.05 8.21 8.52 7.96 0.986666667 8.23 445.68 441.3 411.55 45.59333333 432.8433333 1.08E-56 3.241779451 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding" GO:0002218///activation of innate immune response+++GO:0035458///cellular response to interferon-beta 623131 623131 'Prr19' mRNA 5 5 4 0.23 0.19 0.2 0 0.13 0 0.206666667 0.043333333 0 3 0 4.666666667 1 0.236367216 -2.21546912 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 623230 623230 'Tmem200b' mRNA 12.74 7.19 6.36 0.35 0.22 0.17 0.23 0.21 0.18 0.246666667 0.206666667 7.14 9.47 8.27 8.763333333 8.293333333 0.958547891 -0.062416774 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 623279 623279 'Dok6' mRNA 64 46 58 0.33 0.23 0.32 0.01 0.03 0.03 0.293333333 0.023333333 2 6 7 56 5 8.27E-10 -3.496875719 GO:0005737///cytoplasm GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0043410///positive regulation of MAPK cascade 623474 623474 'Rad54b' mRNA 9 5 15 0.17 0.09 0.3 0.82 0.87 0.87 0.186666667 0.853333333 50 54.1 54.99 9.666666667 53.03 1.92E-06 2.422683389 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0015616///DNA translocase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0008340///determination of adult lifespan+++GO:0009410///response to xenobiotic stimulus+++GO:0010212///response to ionizing radiation+++GO:0042493///response to drug 623505 623505 'Gm6436' mRNA 0 0 0.99 0 0 0.19 0 0 0 0.063333333 0 0 0 0 0.33 0 623534 623534 'Nme9' mRNA 123 134 121 10.61 11.46 11.08 1.06 0.77 0.94 11.05 0.923333333 14 10 12 126 12 2.14E-21 -3.404468821 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0003674///molecular_function+++GO:0004550///nucleoside diphosphate kinase activity GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0008150///biological_process 623661 623661 'Lipt1' mRNA 140.74 149 142.76 5.42 5.39 5.43 3.41 3.7 4.17 5.413333333 3.76 104.44 107 121 144.1666667 110.8133333 0.103570076 -0.387780801 00785///Lipoic acid metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0017118///lipoyltransferase activity" GO:0006464///cellular protein modification process+++GO:0009249///protein lipoylation 623734 623734 'Vmn2r85' mRNA 2 2 4 0.03 0.03 0.07 0 0 0 0.043333333 0 0 0 0 2.666666667 0 0.131756262 -3.887924569 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 623781 623781 'Gm14137' mRNA 21 26 18 0.38 0.46 0.34 0.28 0.27 0.27 0.393333333 0.273333333 18 17 17 21.66666667 17.33333333 0.639239121 -0.328822744 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly 623898 623898 'Gm6460' mRNA 1.33 2.5 4.06 0.11 0.2 0.35 0 0 0.28 0.22 0.093333333 0 0 3.73 2.63 1.243333333 0.635513627 -1.252359712 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 624219 624219 'Angptl8' mRNA 16 11 13 1.23 0.84 1.06 1.21 0.69 0.97 1.043333333 0.956666667 18 10 14 13.33333333 14 0.95347014 0.053625257 04979///Cholesterol metabolism GO:0005576///extracellular region GO:0005179///hormone activity GO:0006006///glucose metabolic process+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0010954///positive regulation of protein processing+++GO:0019216///regulation of lipid metabolic process+++GO:0044255///cellular lipid metabolic process+++GO:0044342///type B pancreatic cell proliferation+++GO:0045444///fat cell differentiation+++GO:0048469///cell maturation+++GO:0050746///regulation of lipoprotein metabolic process+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0070328///triglyceride homeostasis 624224 624224 'Clrn2' mRNA 143 160 127 9.83 10.88 9.26 0.72 1.11 0.62 9.99 0.816666667 12 18 10 143.3333333 13.33333333 2.44E-23 -3.433249664 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032421///stereocilium bundle GO:0003674///molecular_function GO:0007605///sensory perception of sound+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0120045///stereocilium maintenance 624681 624681 'Btnl6' mRNA 1 1 0 0.04 0.04 0 0.06 0 0 0.026666667 0.02 2 0 0 0.666666667 0.666666667 0.998696207 -0.007351681 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0045062///extrathymic T cell selection+++GO:0050852///T cell receptor signaling pathway 624866 624866 'Lekr1' mRNA 485 432 439 8.26 7.12 7.77 3.03 3.79 3.4 7.716666667 3.406666667 181 216 186 452 194.3333333 1.74E-16 -1.228443315 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 624957 624957 'H2ab3' mRNA 0 0 1 0 0 0.12 0 0.21 0 0.04 0.07 0 2 0 0.333333333 0.666666667 0.863090843 0.906589207 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035327///transcriptionally active chromatin GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 625068 625068 'Vmn2r84' mRNA 1 2 0 0.02 0.04 0 0 0 0 0.02 0 0 0 0 1 0 0.616323562 -2.415498512 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 625098 625098 'Slc38a6' mRNA 1605.66 1612.97 1621.78 19.64 19.36 20.99 16.85 14.74 16.97 19.99666667 16.18666667 1557.68 1324.99 1512.06 1613.47 1464.91 0.096582442 -0.153100765 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006868///glutamine transport 625109 625109 'Vmn2r86' mRNA 4 4 5.72 0.09 0.09 0.13 0.02 0 0.02 0.103333333 0.013333333 1 0 1 4.573333333 0.666666667 0.155317775 -2.723789887 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 625131 625131 'Vmn2r87' mRNA 2 5 2.29 0.04 0.11 0.05 0 0.04 0 0.066666667 0.013333333 0 2 0 3.096666667 0.666666667 0.361830858 -2.15358628 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 625249 625249 'Gpx4' mRNA 17408 17394 15918 1478.05 1463.91 1435.7 1577.19 1633.22 1616.79 1459.22 1609.066667 21198 21387 20922 16906.66667 21169 2.28E-11 0.314097187 00480///Glutathione metabolism+++04216///Ferroptosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0047066///phospholipid-hydroperoxide glutathione peroxidase activity GO:0006325///chromatin organization+++GO:0006749///glutathione metabolic process+++GO:0006979///response to oxidative stress+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007568///aging+++GO:0019369///arachidonic acid metabolic process+++GO:0019372///lipoxygenase pathway+++GO:0032355///response to estradiol+++GO:0050727///regulation of inflammatory response+++GO:0051258///protein polymerization+++GO:0110076///negative regulation of ferroptosis 625281 625281 'Gm6570' mRNA 1.7 0 0 0.47 0 0 0.17 0 0 0.156666667 0.056666667 0.69 0 0 0.566666667 0.23 0.863090843 -0.97353728 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 625286 625286 'Tmem236' mRNA 0 2 0 0 0.03 0 0.04 0.09 0.12 0.01 0.083333333 3 6 8 0.666666667 5.666666667 0.092084143 3.102973473 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 625328 625328 'H3f3c' mRNA 75.16 73.08 73.31 4.59 4.42 4.75 4.43 4.96 6.02 4.586666667 5.136666667 83.18 90.68 109.12 73.85 94.32666667 0.273902048 0.340756022 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0005634///nucleus 625360 625360 'BC147527' mRNA 21 27 14 0.74 0.9 0.52 9.33 8.19 6.63 0.72 8.05 322 270 218 20.66666667 270 6.04E-40 3.699169867 625424 625424 'Gm6583' mRNA 14 10 4 0.35 0.24 0.11 0.15 0.11 0.07 0.233333333 0.11 7 5 3 9.333333333 5 0.425805637 -0.899190578 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 625464 625464 'Gm6588' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 625591 625591 'Cldn34c2' mRNA 15.08 11.6 16.07 1.17 0.89 1.45 0.88 0.4 1.12 1.17 0.8 12.98 2.52 15.96 14.25 10.48666667 0.571704558 -0.558645531 GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0005198///structural molecule activity GO:0007155///cell adhesion+++GO:0070830///bicellular tight junction assembly 625638 625638 'Fam43b' mRNA 5 3 0 0.12 0.07 0 0.12 0.02 0.02 0.063333333 0.053333333 6 1 1 2.666666667 2.666666667 0.999712891 7.63E-04 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 625662 625662 'Ankrd31' mRNA 3 3 3 0.03 0.03 0.03 0 0.01 0.02 0.03 0.01 0 1 2 3 1 0.456473589 -1.589254375 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0005515///protein binding GO:0006310///DNA recombination+++GO:0007129///synapsis+++GO:0010780///meiotic DNA double-strand break formation involved in reciprocal meiotic recombination+++GO:0051321///meiotic cell cycle+++GO:1903343///positive regulation of meiotic DNA double-strand break formation 625801 625801 'Gm6625' mRNA 1 0 1 0.06 0 0.07 0.33 0.34 0.23 0.043333333 0.3 6 6 4 0.666666667 5.333333333 0.096403586 2.978002947 626053 626053 'Gm6647' mRNA 10 8 6.69 0.65 0.51 0.46 0.06 0.06 0 0.54 0.04 1 1 0 8.23 0.666666667 0.023506083 -3.590922124 626067 626067 'Gm6650' mRNA 1 1 1 0.04 0.04 0.04 0 0 0 0.04 0 0 0 0 1 0 0.568344116 -2.455252046 626316 626316 'Zfp987' mRNA 0 1.09 0 0 0.02 0 0.09 0.05 0.07 0.006666667 0.07 5.11 2.66 3.92 0.363333333 3.896666667 0.163355264 3.198147334 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 626359 626359 'Wdr93' mRNA 72 77 80 1.69 1.81 1.99 0.59 0.42 0.47 1.83 0.493333333 29 20 22 76.33333333 23.66666667 2.63E-06 -1.705735002 GO:0005747///mitochondrial respiratory chain complex I "GO:0016651///oxidoreductase activity, acting on NAD(P)H" GO:0022900///electron transport chain 626391 626391 'Zfp951' mRNA 59.76 51.83 52.25 1.22 1.06 1.12 1.35 1.77 0.94 1.133333333 1.353333333 74.38 96.89 52.04 54.61333333 74.43666667 0.239579781 0.444650769 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 626415 626415 '4930467E23Rik' mRNA 468.26 483.78 572.72 5.77 5.83 7.44 3.67 3.29 3.58 6.346666667 3.513333333 345.34 297.82 321.98 508.2533333 321.7133333 3.61E-06 -0.679281943 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 626578 626578 'Gbp10' mRNA 1038.45 1137.23 1084.37 16 17.24 17.72 15.39 15.68 12.28 16.98666667 14.45 1149.73 1144.26 888.31 1086.683333 1060.766667 0.75009672 -0.047632345 GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0042832///defense response to protozoan+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071346///cellular response to interferon-gamma 626596 626596 'Rgs22' mRNA 68 69 75 0.88 0.86 1.02 0.45 0.42 0.39 0.92 0.42 43 34 32 70.66666667 36.33333333 0.005339551 -0.976014328 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton GO:0001965///G-protein alpha-subunit binding GO:0009966///regulation of signal transduction+++GO:0009968///negative regulation of signal transduction 626615 626615 'Apol11a' mRNA 1 0 0 0.03 0 0 0 0 0.02 0.01 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 626802 626802 'Gm14322' mRNA 693.32 710.35 706.96 8.97 9.03 9.7 8.08 8.33 7.76 9.233333333 8.056666667 715.45 722.48 666.48 703.5433333 701.47 0.903243001 -0.01655372 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 626832 626832 'Gm6710' mRNA 51.24 52.92 59.24 0.91 0.9 1.68 1.08 1.54 1.13 1.163333333 1.25 55.6 91.81 63.53 54.46666667 70.31333333 0.365598742 0.356442482 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 626834 626834 'Klk13' mRNA 2 3 0 0.12 0.12 0 0.03 0 0.03 0.08 0.02 1 0 1 1.666666667 0.666666667 0.679493967 -1.307587939 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0030141///secretory granule GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016485///protein processing 626848 626848 'Zfp971' mRNA 399.85 398.48 395.81 15.81 15.7 15.95 13.34 15.03 13.55 15.82 13.97333333 394.55 444.9 375.08 398.0466667 404.8433333 0.940111082 0.013876584 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 626854 626854 'Gm38396' mRNA 554.05 581.76 600.84 14.27 14.82 16.59 10.53 10.01 11.62 15.22666667 10.72 467.26 432.65 504.04 578.8833333 467.9833333 0.012588506 -0.320272123 05168///Herpes simplex virus 1 infection GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated" 626858 626858 'Gm6713' mRNA 18.45 7.41 8.95 0.12 0.05 0.07 0.02 0.01 0.03 0.08 0.02 2.49 1.91 5.18 11.60333333 3.193333333 0.066909539 -2.050827419 626870 626870 'Gm11992' mRNA 320 296 338 7.46 6.79 8.35 1.44 1.45 2.07 7.533333333 1.653333333 71 70 99 318 80 2.01E-23 -2.005475061 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 626940 626940 'Gm6721' mRNA 15.09 13.58 5.88 0.08 0.07 0.04 0.05 0.02 0 0.063333333 0.023333333 10.5 4.94 0 11.51666667 5.146666667 0.298095757 -1.243078969 627035 627035 'Gm6729' mRNA 37.13 30.36 16.68 0.25 0.21 0.12 0.03 0.02 0.05 0.193333333 0.033333333 5 2 8.2 28.05666667 5.066666667 6.82E-04 -2.468678078 627049 627049 'Zfp800' mRNA 502 452 356 5.8 5.14 4.46 4.17 3.81 4.54 5.133333333 4.173333333 423 374 441 436.6666667 412.6666667 0.625266731 -0.088810592 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 627081 627081 'Xlr5b' mRNA 0 0 1.19 0 0 0.14 0 0 0 0.046666667 0 0 0 0 0.396666667 0 0.863090843 -0.97353728 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 627191 627191 'Syndig1l' mRNA 1 2 3 0.02 0.04 0.07 0 0.02 0 0.043333333 0.006666667 0 1 0 2 0.333333333 0.370649537 -2.508800057 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 627214 627214 'Insyn2a' mRNA 367.29 397 284 2.31 2.42 1.89 1.79 1.7 1.91 2.206666667 1.8 334 317 307.03 349.43 319.3433333 0.446912024 -0.136041703 GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0045202///synapse GO:0005515///protein binding GO:0060080///inhibitory postsynaptic potential 627280 627280 'Vmn1r90' mRNA 2 0 0 0.14 0 0 0.12 0.13 0.13 0.046666667 0.126666667 2 2 2 0.666666667 2 0.572622425 1.590884362 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 627302 627302 'Gm14092' mRNA 7 3 2 0.22 0.09 0.07 0.03 0 0.03 0.126666667 0.02 1 0 1 4 0.666666667 0.200088392 -2.589525093 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 627352 627352 'Morf4l1b' mRNA 1698.83 1778.55 1325.48 57.63 59.48 47.7 66.79 64.56 60.48 54.93666667 63.94333333 2262.46 2134.41 1982.34 1600.953333 2126.403333 7.53E-06 0.402909639 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 627375 627375 'Gm6750' mRNA 919.36 963.57 1007.06 50.37 52.16 58.54 49.11 48.95 47.93 53.69 48.66333333 1028.4 999.59 970.28 963.33 999.4233333 0.769341814 0.038830527 627626 627626 'Ptchd4' mRNA 138.24 107 116 0.75 0.57 0.72 0.17 0.24 0.26 0.68 0.223333333 51.18 46.2 49 120.4133333 48.79333333 1.81E-06 -1.318649847 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 627872 627872 'Dnah7a' mRNA 57.9 75.99 49.26 0.28 0.36 0.29 0.04 0.04 0.07 0.31 0.05 10.13 8.99 15 61.05 11.37333333 1.18E-07 -2.460832347 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036156///inner dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0036159///inner dynein arm assembly 627975 627975 'Gm6818' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 628053 628053 'Gm14725' mRNA 0 0 1 0 0 0.09 0 0 0 0.03 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 628100 628100 'Fbxo39' mRNA 3 3 0 0.1 0.1 0 0.03 0.03 0.24 0.066666667 0.1 1 1 8 2 3.333333333 0.736640323 0.759035511 GO:0019005///SCF ubiquitin ligase complex GO:0003674///molecular_function GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 628147 628147 'Gm2004' mRNA 114.81 118.99 119.4 4.29 3.79 2.65 2.41 3.12 3.29 3.576666667 2.94 97.73 97.19 95.98 117.7333333 96.96666667 0.276632472 -0.293112995 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 628308 628308 'Zfp970' mRNA 2231.14 2473.27 2338.34 22.17 24.74 24.96 22.44 19.7 21.09 23.95666667 21.07666667 2576.74 2219.18 2357.88 2347.583333 2384.6 0.931060177 0.008959657 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 628705 628705 'Phf11c' mRNA 13.54 25.81 34.21 0.5 0.94 1.34 0.92 0.2 0.35 0.926666667 0.49 28.83 6.12 10.53 24.52 15.16 0.33732269 -0.748722297 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 628746 628746 'Rybp-ps' mRNA 18.68 24.65 10.71 0.23 0.3 0.14 0.18 0.18 0.37 0.223333333 0.243333333 17.16 16.93 33.19 18.01333333 22.42666667 0.653744251 0.3468647 628813 628813 'Gm11437' mRNA 5 3 1 0.25 0.15 0.05 0.09 0 0 0.15 0.03 2 0 0 3 0.666666667 0.363332241 -2.180196514 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 628854 628854 'Gm15517' mRNA 0 1 0 0 0.74 0 0 0 0.68 0.246666667 0.226666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 628870 628870 'Otogl' mRNA 4778 4772 4266 28.38 28.66 27.14 7.81 5.97 7.28 28.06 7.02 1500 1152 1386 4605.333333 1346 4.73E-116 -1.78653102 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0003674///molecular_function+++GO:0046556///alpha-L-arabinofuranosidase activity GO:0007605///sensory perception of sound+++GO:0008150///biological_process+++GO:0046373///L-arabinose metabolic process 628900 628900 'Serpina3i' mRNA 22.61 34.28 29.7 1.12 2.15 1.21 8.62 7.83 8.23 1.493333333 8.226666667 198.01 190.93 187.55 28.86333333 192.1633333 5.74E-25 2.746396204 GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0034097///response to cytokine+++GO:0043434///response to peptide hormone 629016 629016 'Zfp953' mRNA 64.88 54.66 56.81 0.75 0.62 0.7 0.65 0.72 0.59 0.69 0.653333333 64.95 70.42 56.88 58.78333333 64.08333333 0.790215702 0.115709611 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 629059 629059 'Fam124a' mRNA 237 198 160 3.62 2.98 2.59 0.59 0.68 0.48 3.063333333 0.583333333 44.08 50 35.02 198.3333333 43.03333333 3.21E-18 -2.211485769 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 629114 629114 'Defb23' mRNA 1 0 0 0.12 0 0 0 0 0 0.04 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region GO:0003674///molecular_function GO:0006952///defense response+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response 629147 629147 'Ctxn3' mRNA 1479 1624 1588 75.5 74.51 80.42 64.63 57.44 63.39 76.81 61.82 1439 1301 1323 1563.666667 1354.333333 0.012360777 -0.220997786 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 629242 629242 'Gm6958' mRNA 177.83 183.93 138.01 2.54 2.58 2.09 2.76 2.63 2.68 2.403333333 2.69 222.05 207.23 209.33 166.59 212.87 0.07663266 0.349777516 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 629303 629303 'Heatr9' mRNA 4 2 3 0.1 0.06 0.08 0.08 0 0 0.08 0.026666667 3 0 0 3 1 0.481151985 -1.620926478 GO:0005575///cellular_component GO:0002244///hematopoietic progenitor cell differentiation 629378 629378 'Dact3' mRNA 78 89 36 1.52 1.71 0.74 0.42 0.61 0.6 1.323333333 0.543333333 25 35 34 67.66666667 31.33333333 0.008595429 -1.103796179 GO:0005737///cytoplasm GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0051018///protein kinase A binding+++GO:0070097///delta-catenin binding GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway 629499 629499 'Mroh8' mRNA 0 6.96 9 0 0.11 0.16 0 0.03 0 0.09 0.01 0 2.1 0 5.32 0.7 0.168336297 -2.930873927 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 629595 629595 'Gm6988' mRNA 193.71 195.01 230.33 32.73 32.95 41.32 37.5 45.28 40.19 35.66666667 40.99 252.39 295.64 260.21 206.35 269.4133333 0.052398093 0.370311185 629747 629747 'Spint3' mRNA 0 0 1 0 0 0.15 0 0 0.13 0.05 0.043333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity 629756 629756 'Wfdc10' mRNA 0 0 2 0 0 0.42 0 0 0 0.14 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 629970 629970 'Cd300ld2' mRNA 0 1 2.29 0 0.04 0.11 0.36 0.17 0.33 0.05 0.286666667 9.25 4.27 8.06 1.096666667 7.193333333 0.070567623 2.774352363 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity GO:0008150///biological_process 630077 630077 'LOC630077' mRNA 6.02 0 1 0.15 0 0.03 0.09 0.13 0.11 0.06 0.11 4 5.98 4.98 2.34 4.986666667 0.631295655 0.892516199 630146 630146 'Cd101' mRNA 6 8 7 0.07 0.09 0.09 0.52 0.44 0.26 0.083333333 0.406666667 52 43 25 7 40 2.07E-05 2.500368436 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002763///positive regulation of myeloid leukocyte differentiation 630294 630294 'Gm7030' mRNA 5.74 7.13 2.04 0.42 0.52 0.16 0.45 0.48 0.46 0.366666667 0.463333333 7.01 7.39 7 4.97 7.133333333 0.651989731 0.590022037 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0042605///peptide antigen binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 630537 630537 'Dcpp2' mRNA 2 0 0 0.25 0 0 0.11 0 0.23 0.083333333 0.113333333 1 0 2 0.666666667 1 0.874307774 0.589641014 GO:0005615///extracellular space GO:0003674///molecular_function GO:0008150///biological_process 630579 630579 'Zfp808' mRNA 151.58 139.44 129.52 1.93 1.67 1.68 1.29 1.44 1.12 1.76 1.283333333 124.88 122.63 116.11 140.18 121.2066667 0.380224621 -0.22130741 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 630836 630836 '2010315B03Rik' mRNA 771.95 828.12 792.27 16.13 17.02 17.34 11.35 10.5 9.57 16.83 10.47333333 630.13 571 515.01 797.4466667 572.0466667 8.68E-06 -0.491662994 GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 631145 631145 'Fam90a1b' mRNA 1 0 0 0.02 0 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 631323 631323 'Gm12250' mRNA 111 100 104 2.27 2.02 2.26 8.03 8.86 9.42 2.183333333 8.77 451 486 512 105 483 3.96E-43 2.190749108 GO:0016020///membrane GO:0005525///GTP binding 631415 631415 'Gm20760' mRNA 1.99 2 0 0.11 0.1 0 0.18 0.05 0 0.07 0.076666667 4 1 0 1.33 1.666666667 0.817847257 0.738731464 631584 631584 'Catspere1' mRNA 125.25 114 54.48 2.73 2.64 0.92 0.35 0.4 0.31 2.096666667 0.353333333 12.99 21.53 19.54 97.91 18.02 1.15E-09 -2.487769148 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0003674///molecular_function GO:0008150///biological_process 631624 631624 'Gm7072' mRNA 298 357.27 311.89 4.14 4.86 4.5 4.51 3.83 4.01 4.5 4.116666667 362.72 310 317.51 322.3866667 330.0766667 0.909045533 0.02191037 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 631797 631797 'Fer1l6' mRNA 57 64 53 0.46 0.53 0.47 0.08 0.11 0.18 0.486666667 0.123333333 11 16 26 58 17.66666667 1.01E-04 -1.721316409 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0007009///plasma membrane organization+++GO:0009617///response to bacterium 631990 631990 'Cdr1' mRNA 5 12 10 0.12 0.29 0.26 0.15 0.17 0.28 0.223333333 0.2 7 8 13 9 9.333333333 0.974809557 0.040944304 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 632126 632126 'Btnl4' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 632671 632671 'Vmn2r18' mRNA 2 3 2 0.04 0.06 0.05 0 0 0.02 0.05 0.006666667 0 0 1 2.333333333 0.333333333 0.300416676 -2.709642034 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 632687 632687 'Marchf10' mRNA 7 4 5 0.12 0.07 0.1 0.18 0.18 0.19 0.096666667 0.183333333 8 8 8 5.333333333 8 0.628527099 0.573265223 GO:0005575///cellular_component GO:0008270///zinc ion binding GO:0008150///biological_process 632778 632778 'Erich4' mRNA 2 0 0 0.15 0 0 0.07 0.14 0.14 0.05 0.116666667 1 2 2 0.666666667 1.666666667 0.666836161 1.334349608 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 633057 633057 'Gm7102' mRNA 36.29 35.91 31.19 1.31 1.27 1.19 0.94 0.88 0.95 1.256666667 0.923333333 30.15 27.36 29.32 34.46333333 28.94333333 0.642307959 -0.256506752 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0030496///midbody GO:0003674///molecular_function GO:0008150///biological_process 633285 633285 'Rbm46' mRNA 25 17 18 0.38 0.3 0.4 0.33 0.32 0.31 0.36 0.32 17 20 18 20 18.33333333 0.863090843 -0.134619483 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0001829///trophectodermal cell differentiation+++GO:0048255///mRNA stabilization 633640 633640 'Tmem267' mRNA 89 93 101 2.75 2.92 3.53 1.94 2.19 2.27 3.066666667 2.133333333 70 75 81 94.33333333 75.33333333 0.269724881 -0.338133517 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 633979 633979 'Ak9' mRNA 307 290 278 2.71 2.52 2.61 0.22 0.25 0.22 2.613333333 0.23 29 32 28 291.6666667 29.66666667 4.61E-46 -3.308280081 00230///Purine metabolism+++00240///Pyrimidine metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0031965///nuclear membrane GO:0004017///adenylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019205///nucleobase-containing compound kinase activity+++GO:0050145///nucleoside monophosphate kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006174///dADP phosphorylation+++GO:0006186///dGDP phosphorylation+++GO:0006756///AMP phosphorylation+++GO:0006757///ATP generation from ADP+++GO:0016310///phosphorylation+++GO:0061508///CDP phosphorylation+++GO:0061565///dAMP phosphorylation+++GO:0061566///CMP phosphorylation+++GO:0061567///dCMP phosphorylation+++GO:0061568///GDP phosphorylation+++GO:0061569///UDP phosphorylation+++GO:0061570///dCDP phosphorylation+++GO:0061571///TDP phosphorylation 634104 634104 'Olfr287' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04740///Olfactory transduction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 634731 634731 'Susd1' mRNA 104.68 111.19 89 1.57 1.67 1.35 1.43 1.18 1.12 1.53 1.243333333 106 83.08 82 101.6233333 90.36 0.583749235 -0.176236837 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 634882 634882 'Itih5l-ps' mRNA 14 12 4 0.2 0.14 0.05 0.04 0.09 0.07 0.13 0.066666667 3 7 5 10 5 0.366833219 -0.987637596 635169 635169 'CK137956' mRNA 0 0 0.55 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.183333333 0 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 635253 635253 'Usp51' mRNA 13 17 12 0.33 0.42 0.32 0.09 0.13 0.34 0.356666667 0.186666667 4 6 15 14 8.333333333 0.413323472 -0.751403914 GO:0005694///chromosome GO:0003682///chromatin binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010564///regulation of cell cycle process+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:2001020///regulation of response to DNA damage stimulus+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 635702 635702 'Naaladl2' mRNA 497 538 488 2.71 2.88 2.83 0.39 0.4 0.43 2.806666667 0.406666667 83 83 89 507.6666667 85 8.04E-60 -2.589234369 GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009617///response to bacterium 635895 635895 'Gm7168' mRNA 9.81 7 0 0.36 0.25 0 0 0 0.07 0.203333333 0.023333333 0 0 2 5.603333333 0.666666667 0.15749465 -2.973247284 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction 636104 636104 'Cfap47' mRNA 355 278 307 1.93 1.49 1.77 0.22 0.12 0.11 1.73 0.15 46 25 23 313.3333333 31.33333333 1.38E-40 -3.338230975 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 636741 636741 'Zfp964' mRNA 190 183 173 2.49 2.47 2.16 1.26 0.87 1.29 2.373333333 1.14 123 83 122.1 182 109.3666667 8.21E-04 -0.748442412 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 636808 636808 'Cntnap5a' mRNA 4 6 7 0.02 0.03 0.04 0 0 0 0.03 0 1 1 1 5.666666667 1 0.111241566 -2.521800689 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004190///aspartic-type endopeptidase activity GO:0006508///proteolysis+++GO:0007155///cell adhesion 636931 636931 'Trim71' mRNA 67 54 68 0.69 0.54 0.74 0.09 0.07 0.03 0.656666667 0.063333333 10 8 3 63 7 4.23E-10 -3.188033671 04361///Axon regeneration+++05206///MicroRNAs in cancer GO:0000932///P-body+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0030371///translation repressor activity+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000209///protein polyubiquitination+++GO:0001843///neural tube closure+++GO:0007275///multicellular organism development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010586///miRNA metabolic process+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0017148///negative regulation of translation+++GO:0021915///neural tube development+++GO:0031047///gene silencing by RNA+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051246///regulation of protein metabolic process+++GO:0051865///protein autoubiquitination+++GO:0060964///regulation of gene silencing by miRNA+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0071310///cellular response to organic substance+++GO:0072089///stem cell proliferation+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000637///positive regulation of gene silencing by miRNA 637004 637004 'Vmn2r3' mRNA 0 1.04 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.346666667 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 637053 637053 'Vmn2r4' mRNA 0 0 3.74 0 0 0.08 0 0 0 0.026666667 0 0 0 0 1.246666667 0 0.625198426 -2.527571966 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 637079 637079 'Iqcn' mRNA 3 1 3 0.01 0.01 0.02 0.11 0.09 0.18 0.013333333 0.126666667 22 14 26 2.333333333 20.66666667 4.80E-04 3.127320422 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 637277 637277 'Sycp2l' mRNA 0 0 1 0 0 0.02 0 0.02 0 0.006666667 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 "GO:0000775///chromosome, centromeric region+++GO:0000779///condensed chromosome, centromeric region+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0003674///molecular_function GO:0000080///mitotic G1 phase+++GO:0042697///menopause+++GO:0060548///negative regulation of cell death+++GO:0140013///meiotic nuclear division 637515 637515 'Nlrp1b' mRNA 64.89 54.45 59.25 0.53 0.44 0.55 1 1.11 0.8 0.506666667 0.97 111.16 121.11 91.64 59.53 107.97 0.002760186 0.855609943 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0061702///inflammasome complex+++GO:0072558///NLRP1 inflammasome complex GO:0000166///nucleotide binding+++GO:0003690///double-stranded DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0043621///protein self-association GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0012501///programmed cell death+++GO:0030163///protein catabolic process+++GO:0032610///interleukin-1 alpha production+++GO:0032611///interleukin-1 beta production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0042981///regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051260///protein homooligomerization+++GO:0051402///neuron apoptotic process+++GO:0051607///defense response to virus+++GO:0070269///pyroptosis+++GO:0097264///self proteolysis+++GO:1904784///NLRP1 inflammasome complex assembly 637776 637776 'Zfp977' mRNA 55 63.16 50 1.75 1.98 1.69 0.64 0.68 0.8 1.806666667 0.706666667 23 24 27.99 56.05333333 24.99666667 0.002783497 -1.190859669 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 63828 63828 'Fn3k' mRNA 265 285 301 14.84 16.35 16.83 5.47 5.44 5.58 16.00666667 5.496666667 129 125 112 283.6666667 122 1.16E-11 -1.232017805 GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030387///fructosamine-3-kinase activity+++GO:0102193///protein-ribulosamine 3-kinase activity+++GO:0102194///protein-fructosamine 3-kinase activity GO:0016310///phosphorylation+++GO:0030389///fructosamine metabolic process+++GO:0030855///epithelial cell differentiation+++GO:0036525///protein deglycation 638532 638532 'Gm7241' mRNA 0 2 0 0 0.34 0 0.14 0.16 0.47 0.113333333 0.256666667 0.92 1 3 0.666666667 1.64 0.780741678 1.03479338 63856 63856 'Taf8' mRNA 901 885 956 17.31 16.85 19.78 11.27 11.86 12.34 17.98 11.82333333 776 712 752 914 746.6666667 0.003737529 -0.306434522 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0001112///DNA-templated transcriptional open complex formation+++GO:0001833///inner cell mass cell proliferation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0051457///maintenance of protein location in nucleus 63857 63857 'Bco1' mRNA 7.21 1 0 0.17 0.02 0 0 0.02 0.02 0.063333333 0.013333333 0 1 1 2.736666667 0.666666667 0.455482153 -1.974124307 00830///Retinol metabolism+++01240///Biosynthesis of cofactors "GO:0003834///beta-carotene 15,15'-monooxygenase activity+++GO:0004497///monooxygenase activity+++GO:0010436///carotenoid dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0001523///retinoid metabolic process+++GO:0016121///carotene catabolic process+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:1901810///beta-carotene metabolic process 63859 63859 'Impg1' mRNA 31.31 19.74 31.51 0.19 0.12 0.2 0.02 0.01 0.1 0.17 0.043333333 3.4 1 18.63 27.52 7.676666667 0.020705194 -1.897907293 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0033165///interphotoreceptor matrix+++GO:0042995///cell projection GO:0005540///hyaluronic acid binding+++GO:0008201///heparin binding+++GO:0035374///chondroitin sulfate binding GO:0007601///visual perception+++GO:0030198///extracellular matrix organization 63872 63872 'Zfp296' mRNA 5 7 7 0.19 0.27 0.29 1.61 1.2 1.11 0.25 1.306666667 48 35 32 6.333333333 38.33333333 1.15E-05 2.581232549 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003674///molecular_function+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II 63873 63873 'Trpv4' mRNA 1050 1177 1005 17.81 19.68 18.1 21.39 21.35 19.7 18.53 20.81333333 1444 1410 1294 1077.333333 1382.666667 6.77E-05 0.349833639 04218///Cellular senescence+++04750///Inflammatory mediator regulation of TRP channels+++05418///Fluid shear stress and atherosclerosis GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0030864///cortical actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005034///osmosensor activity+++GO:0005080///protein kinase C binding+++GO:0005216///ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0015275///stretch-activated, cation-selective, calcium channel activity+++GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding+++GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding+++GO:0051015///actin filament binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002024///diet induced thermogenesis+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006970///response to osmotic stress+++GO:0006971///hypotonic response+++GO:0007015///actin filament organization+++GO:0007043///cell-cell junction assembly+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007231///osmosensory signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0010977///negative regulation of neuron projection development+++GO:0030103///vasopressin secretion+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0032496///response to lipopolysaccharide+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032868///response to insulin+++GO:0034220///ion transmembrane transport+++GO:0034605///cellular response to heat+++GO:0042538///hyperosmotic salinity response+++GO:0042593///glucose homeostasis+++GO:0043117///positive regulation of vascular permeability+++GO:0043622///cortical microtubule organization+++GO:0045989///positive regulation of striated muscle contraction+++GO:0046330///positive regulation of JNK cascade+++GO:0046785///microtubule polymerization+++GO:0047484///regulation of response to osmotic stress+++GO:0050729///positive regulation of inflammatory response+++GO:0050891///multicellular organismal water homeostasis+++GO:0055085///transmembrane transport+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070509///calcium ion import+++GO:0070542///response to fatty acid+++GO:0070588///calcium ion transmembrane transport+++GO:0071470///cellular response to osmotic stress+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071642///positive regulation of macrophage inflammatory protein 1 alpha production+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:0097009///energy homeostasis+++GO:0097497///blood vessel endothelial cell delamination+++GO:0098703///calcium ion import across plasma membrane+++GO:1900744///regulation of p38MAPK cascade+++GO:1902656///calcium ion import into cytosol+++GO:1903444///negative regulation of brown fat cell differentiation+++GO:1903715///regulation of aerobic respiration+++GO:2000340///positive regulation of chemokine (C-X-C motif) ligand 1 production 63913 63913 'Niban1' mRNA 121 154 110 1.47 1.9 1.48 4.4 3.96 3.52 1.616666667 3.96 410 354 322 128.3333333 362 2.06E-17 1.486935787 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006417///regulation of translation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045727///positive regulation of translation 639281 639281 'Gm10382' mRNA 31 27 12 1.24 1.06 0.51 1.25 1.96 1.47 0.936666667 1.56 36 55 41 23.33333333 44 0.064771471 0.920173233 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 63953 63953 'Dusp10' mRNA 558 598 492 12.85 13.16 11.68 5.41 3.8 4.61 12.56333333 4.606666667 259 194 243 549.3333333 232 1.85E-19 -1.254066502 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0008432///JUN kinase binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0033549///MAP kinase phosphatase activity+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0002819///regulation of adaptive immune response+++GO:0006470///protein dephosphorylation+++GO:0010033///response to organic substance+++GO:0010633///negative regulation of epithelial cell migration+++GO:0016311///dephosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0043508///negative regulation of JUN kinase activity+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045088///regulation of innate immune response+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0046329///negative regulation of JNK cascade+++GO:0048709///oligodendrocyte differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060266///negative regulation of respiratory burst involved in inflammatory response+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090335///regulation of brown fat cell differentiation+++GO:1903753///negative regulation of p38MAPK cascade+++GO:1905042///negative regulation of epithelium regeneration+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 63954 63954 'Rbp7' mRNA 14 18 17 0.63 0.92 1.61 2.28 2.04 2.07 1.053333333 2.13 30 24 22 16.33333333 25.33333333 0.313137095 0.618393798 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005501///retinoid binding+++GO:0005504///fatty acid binding+++GO:0008289///lipid binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding GO:0015908///fatty acid transport 63955 63955 'Cables1' mRNA 48 63 37 0.8 1.01 0.64 1.09 1.15 1.16 0.816666667 1.133333333 77 77 78 49.33333333 77.33333333 0.057117085 0.64444083 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0005515///protein binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle 63958 63958 'Ube4b' mRNA 1536 1561 1392 14.26 14.3 14.03 13.58 11.28 11.93 14.19666667 12.26333333 1625 1324 1386 1496.333333 1445 0.565895401 -0.062237349 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0051082///unfolded protein binding+++GO:0051117///ATPase binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0006457///protein folding+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031175///neuron projection development+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044257///cellular protein catabolic process+++GO:0051865///protein autoubiquitination 63959 63959 'Slc29a1' mRNA 1678 1686 1732 47.07 46.84 50.94 85.07 86.34 86.63 48.28333333 86.01333333 3500 3426 3424 1698.666667 3450 4.41E-49 1.008990482 05034///Alcoholism GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0005326///neurotransmitter transporter activity+++GO:0005337///nucleoside transmembrane transporter activity+++GO:0015211///purine nucleoside transmembrane transporter activity+++GO:0015213///uridine transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity GO:0001504///neurotransmitter uptake+++GO:0006836///neurotransmitter transport+++GO:0007595///lactation+++GO:0015858///nucleoside transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0015862///uridine transport+++GO:0030431///sleep+++GO:0032238///adenosine transport+++GO:0060079///excitatory postsynaptic potential+++GO:0071333///cellular response to glucose stimulus+++GO:0071456///cellular response to hypoxia+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:0080121///AMP transport+++GO:0098810///neurotransmitter reuptake+++GO:1901642///nucleoside transmembrane transport 639774 639774 'Skint8' mRNA 0 1 0 0 0.07 0 0 0.04 0 0.023333333 0.013333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding GO:0001817///regulation of cytokine production+++GO:0050852///T cell receptor signaling pathway 63985 63985 'Gmfb' mRNA 2236.68 2315.21 2426.9 23.77 24.76 27.61 29.73 28.68 28.75 25.38 29.05333333 3826.3 3663.76 3601.21 2326.263333 3697.09 1.51E-19 0.654175137 GO:0003779///actin binding+++GO:0008083///growth factor activity+++GO:0071933///Arp2/3 complex binding GO:0007165///signal transduction+++GO:0007612///learning+++GO:0007626///locomotory behavior+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0071846///actin filament debranching 63986 63986 'Gmfg' mRNA 65.65 55 36.55 1.59 1.32 0.94 10.23 12.13 11.44 1.283333333 11.26666667 485.77 562.22 526.26 52.4 524.75 3.57E-68 3.328987065 GO:0003779///actin binding+++GO:0008083///growth factor activity+++GO:0071933///Arp2/3 complex binding GO:0007165///signal transduction+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0071846///actin filament debranching+++GO:2000249///regulation of actin cytoskeleton reorganization 639910 639910 'Gm20767' mRNA 0.6 1 0 0.03 0.04 0 0 0 0 0.023333333 0 0 0 0 0.533333333 0 0.863090843 -0.97353728 63993 63993 'Slc5a7' mRNA 21 15 26 0.22 0.16 0.3 0.42 0.27 0.34 0.226666667 0.343333333 45 27 34 20.66666667 35.33333333 0.16214682 0.74924901 04725///Cholinergic synapse+++05231///Choline metabolism in cancer GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0045334///clathrin-coated endocytic vesicle GO:0005307///choline:sodium symporter activity+++GO:0005515///protein binding+++GO:0015220///choline transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033265///choline binding "GO:0001701///in utero embryonic development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007271///synaptic transmission, cholinergic+++GO:0007274///neuromuscular synaptic transmission+++GO:0008292///acetylcholine biosynthetic process+++GO:0015871///choline transport+++GO:0042136///neurotransmitter biosynthetic process+++GO:0055085///transmembrane transport" 64008 64008 'Aqp9' mRNA 2 16 3 0.08 0.35 0.09 0.99 0.58 0.7 0.173333333 0.756666667 39 31 37 7 35.66666667 5.85E-04 2.35360945 04613///Neutrophil extracellular trap formation+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0015204///urea transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0015254///glycerol channel activity+++GO:0015265///urea channel activity+++GO:0015267///channel activity GO:0006833///water transport+++GO:0006863///purine nucleobase transport+++GO:0010033///response to organic substance+++GO:0015722///canalicular bile acid transport+++GO:0015791///polyol transport+++GO:0015793///glycerol transport+++GO:0015837///amine transport+++GO:0015855///pyrimidine nucleobase transport+++GO:0046689///response to mercury ion+++GO:0055085///transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0071918///urea transmembrane transport+++GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport 64009 64009 'Syne1' mRNA 10240.13 10087.73 9087.23 16.32 15.88 15.26 7.79 6.57 7.65 15.82 7.336666667 5826.66 4906.73 5744.64 9805.03 5492.676667 1.94E-41 -0.847371072 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030017///sarcomere+++GO:0030496///midbody+++GO:0031965///nuclear membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0043197///dendritic spine+++GO:0044327///dendritic spine head+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0007030///Golgi organization+++GO:0007097///nuclear migration+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0042692///muscle cell differentiation+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048814///regulation of dendrite morphogenesis+++GO:0051642///centrosome localization+++GO:0061886///negative regulation of mini excitatory postsynaptic potential+++GO:0090292///nuclear matrix anchoring at nuclear membrane+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1902017///regulation of cilium assembly+++GO:1903353///regulation of nucleus organization+++GO:2001054///negative regulation of mesenchymal cell apoptotic process 64010 64010 'Sav1' mRNA 68 30 41 1.49 0.62 0.92 1.38 1.52 1.86 1.01 1.586666667 74 80 94 46.33333333 82.66666667 0.026044577 0.825440164 04214///Apoptosis - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0030425///dendrite GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0060090///molecular adaptor activity+++GO:0070699///type II activin receptor binding GO:0001942///hair follicle development+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0030216///keratinocyte differentiation+++GO:0035329///hippo signaling+++GO:0042127///regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043113///receptor clustering+++GO:0045600///positive regulation of fat cell differentiation+++GO:0046620///regulation of organ growth+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0060412///ventricular septum morphogenesis+++GO:0060487///lung epithelial cell differentiation+++GO:0060575///intestinal epithelial cell differentiation+++GO:2000036///regulation of stem cell population maintenance 64011 64011 'Nrgn' mRNA 1 1 2 0.05 0.05 0.1 0.12 0.21 0.34 0.066666667 0.223333333 3 5 8 1.333333333 5.333333333 0.208645545 1.982450756 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0012510///trans-Golgi network transport vesicle membrane+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031966///mitochondrial membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0044327///dendritic spine head+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0005516///calmodulin binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0070300///phosphatidic acid binding" GO:0008306///associative learning+++GO:0021537///telencephalon development+++GO:0035556///intracellular signal transduction+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:1900273///positive regulation of long-term synaptic potentiation 64050 64050 'Yeats4' mRNA 393 405 434 16.66 16.94 19.52 16.24 16.8 16.67 17.70666667 16.57 440 444 437 410.6666667 440.3333333 0.604429715 0.086678758 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane+++GO:0035267///NuA4 histone acetyltransferase complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0070577///lysine-acetylated histone binding+++GO:0140030///modification-dependent protein binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation" 64051 64051 'Sv2a' mRNA 615 744 536 8.48 10.09 7.84 2.5 2.37 2.1 8.803333333 2.323333333 209 193 170 631.6666667 190.6666667 1.15E-33 -1.735444658 04512///ECM-receptor interaction GO:0005783///endoplasmic reticulum+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity GO:0006836///neurotransmitter transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:0014052///regulation of gamma-aminobutyric acid secretion+++GO:0016082///synaptic vesicle priming+++GO:0055085///transmembrane transport 640524 640524 'Sptbn5' mRNA 698.8 771.45 690.71 2.52 2.75 2.65 1.66 1.6 1.67 2.64 1.643333333 530.62 500.6 511.76 720.32 514.3266667 3.01E-06 -0.497649992 GO:0005737///cytoplasm+++GO:0005875///microtubule associated complex+++GO:0005930///axoneme+++GO:0030863///cortical cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0032991///protein-containing complex+++GO:0045179///apical cortex+++GO:0097381///photoreceptor disc membrane GO:0002046///opsin binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019894///kinesin binding+++GO:0030507///spectrin binding+++GO:0032029///myosin tail binding+++GO:0034452///dynactin binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0045505///dynein intermediate chain binding+++GO:0051015///actin filament binding GO:0007030///Golgi organization+++GO:0007041///lysosomal transport 640543 640543 'Tgm7' mRNA 159 149 67 6.12 5.65 2.74 0.47 0.14 0.24 4.836666667 0.283333333 14 4 7 125 8.333333333 1.80E-17 -3.907729115 GO:0005575///cellular_component GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0046872///metal ion binding GO:0018149///peptide cross-linking 64058 64058 'Perp' mRNA 2252 2383 2242 67.83 70.73 71.64 55.79 56.13 53.69 70.06666667 55.20333333 2129 2091 1983 2292.333333 2067.666667 0.030887764 -0.160586119 04115///p53 signaling pathway GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0002934///desmosome organization+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0034113///heterotypic cell-cell adhesion+++GO:0045862///positive regulation of proteolysis+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097186///amelogenesis+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0098609///cell-cell adhesion 64059 64059 'Oxct2a' mRNA 1.48 0 0 0.05 0 0 0.03 0 0 0.016666667 0.01 1 0 0 0.493333333 0.333333333 0.998591786 -0.011756601 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism" GO:0005739///mitochondrion GO:0008260///3-oxoacid CoA-transferase activity+++GO:0008410///CoA-transferase activity+++GO:0016740///transferase activity GO:0006104///succinyl-CoA metabolic process+++GO:0046950///cellular ketone body metabolic process+++GO:0046952///ketone body catabolic process 64074 64074 'Smoc2' mRNA 370 346 392 7.21 6.63 8.1 8.62 7.97 6.73 7.313333333 7.773333333 509 460 385 369.3333333 451.3333333 0.084297133 0.2733417 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071944///cell periphery GO:0005509///calcium ion binding+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding GO:0010595///positive regulation of endothelial cell migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization+++GO:0035470///positive regulation of vascular wound healing+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0045931///positive regulation of mitotic cell cycle+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:2001028///positive regulation of endothelial cell chemotaxis 64075 64075 'Smoc1' mRNA 1984 1968 1802 31.14 30.42 30.02 8.4 9.38 9.11 30.52666667 8.963333333 616 669 646 1918 643.6666667 8.83E-83 -1.584997393 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0046872///metal ion binding+++GO:0050840///extracellular matrix binding GO:0001654///eye development+++GO:0007275///multicellular organism development+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0045667///regulation of osteoblast differentiation+++GO:0060173///limb development 64082 64082 'Popdc2' mRNA 107 130 126 2.75 3.3 3.46 2.75 2.12 2.47 3.17 2.446666667 123 92 107 121 107.3333333 0.524151379 -0.188179556 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0000166///nucleotide binding+++GO:0030552///cAMP binding GO:0002027///regulation of heart rate+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0042391///regulation of membrane potential+++GO:0051146///striated muscle cell differentiation+++GO:0060931///sinoatrial node cell development 64085 64085 'Clstn2' mRNA 537 464 458 3.26 2.57 2.81 0.27 0.38 0.43 2.88 0.36 82 101 88 486.3333333 90.33333333 1.01E-48 -2.43849386 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0050806///positive regulation of synaptic transmission+++GO:0051965///positive regulation of synapse assembly 64095 64095 'Gpr35' mRNA 181.86 146.22 124.18 1.02 0.79 0.73 5.16 5.14 4.11 0.846666667 4.803333333 522.66 512.12 410.89 150.7533333 481.89 6.86E-24 1.670513827 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0048246///macrophage chemotaxis+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0070098///chemokine-mediated signaling pathway+++GO:1901386///negative regulation of voltage-gated calcium channel activity+++GO:1904456///negative regulation of neuronal action potential 64099 64099 'Parvg' mRNA 58 49 33 1.21 1.01 0.73 24.59 20.82 22.15 0.983333333 22.52 1359 1124 1185 46.66666667 1222.666667 5.95E-182 4.701571606 04510///Focal adhesion GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction GO:0003779///actin binding GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030031///cell projection assembly+++GO:0031532///actin cytoskeleton reorganization+++GO:0034446///substrate adhesion-dependent cell spreading 64103 64103 'Tnmd' mRNA 71 49 59 3.23 2.2 2.85 2.85 3.17 2.29 2.76 2.77 72 78 56 59.66666667 68.66666667 0.648779569 0.189969482 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001886///endothelial cell morphogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0016525///negative regulation of angiogenesis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0035990///tendon cell differentiation+++GO:0071773///cellular response to BMP stimulus 64113 64113 'Moap1' mRNA 312.74 334.43 272.89 4.58 4.83 4.25 5.34 4.24 3.5 4.553333333 4.36 419.22 325.61 266.29 306.6866667 337.04 0.555722717 0.126339024 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097190///apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 641340 641340 'Nrbf2' mRNA 404 399 378 12.46 12.58 12.78 19.44 19.04 20.02 12.60666667 19.5 707 683 693 393.6666667 694.3333333 1.30E-13 0.80739306 04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases "GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle+++GO:0035032///phosphatidylinositol 3-kinase complex, class III" GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006914///autophagy+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043550///regulation of lipid kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated" 64136 64136 'Sdf2l1' mRNA 1243 1353 1227 70.05 75.34 73.36 127.28 128.52 125.72 72.91666667 127.1733333 2591 2551 2474 1274.333333 2538.666667 8.71E-45 0.983302477 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0101031///chaperone complex GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding+++GO:0051787///misfolded protein binding GO:0034976///response to endoplasmic reticulum stress+++GO:0035269///protein O-linked mannosylation+++GO:0042981///regulation of apoptotic process+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071218///cellular response to misfolded protein+++GO:0071712///ER-associated misfolded protein catabolic process 641361 641361 'Pinlyp' mRNA 78 99 105 7.42 8.61 10.22 1.69 2.34 2.36 8.75 2.13 21 28 29 94 26 5.68E-08 -1.868088708 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0004859///phospholipase inhibitor activity GO:0008150///biological_process+++GO:0043086///negative regulation of catalytic activity 641376 641376 'Tomm40l' mRNA 874.97 974.99 899.86 16.51 18.12 18.02 17.33 18.29 18.35 17.55 17.99 1054.89 1087.8 1082.71 916.6066667 1075.133333 0.023527526 0.219440564 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0046930///pore complex GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0070678///preprotein binding GO:0006811///ion transport+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0055085///transmembrane transport 64138 64138 'Ctsz' mRNA 4221 4518 4507 174.31 184.06 197.46 723.9 729.24 697.64 185.2766667 716.9266667 20133 19788 18769 4415.333333 19563.33333 5.52E-278 2.134178269 04142///Lysosome+++04210///Apoptosis GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0030426///growth cone+++GO:0031410///cytoplasmic vesicle+++GO:0062023///collagen-containing extracellular matrix+++GO:0099738///cell cortex region GO:0004180///carboxypeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0010757///negative regulation of plasminogen activation+++GO:0010977///negative regulation of neuron projection development+++GO:0032091///negative regulation of protein binding+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:1901214///regulation of neuron death+++GO:2000179///positive regulation of neural precursor cell proliferation 64143 64143 'Ralb' mRNA 650 589 569 16.04 14.45 15.08 42.18 44.78 42.12 15.19 43.02666667 1929 2007 1866 602.6666667 1934 3.77E-85 1.671704154 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++05210///Colorectal cancer+++05212///Pancreatic cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051117///ATPase binding GO:0001928///regulation of exocyst assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0009267///cellular response to starvation+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0051301///cell division+++GO:0060178///regulation of exocyst localization+++GO:0071360///cellular response to exogenous dsRNA+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000786///positive regulation of autophagosome assembly 64144 64144 'Mllt1' mRNA 332 315 364 4.99 4.65 5.81 4.1 4.07 3.7 5.15 3.956666667 314 304 274 337 297.3333333 0.261414795 -0.196264408 05202///Transcriptional misregulation in cancer GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity" 64176 64176 'Sv2b' mRNA 331 323 340 3.24 3.1 3.56 0.19 0.29 0.25 3.3 0.243333333 22 34 28 331.3333333 28 3.87E-52 -3.576893492 04512///ECM-receptor interaction GO:0001669///acrosomal vesicle+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0015031///protein transport+++GO:0016079///synaptic vesicle exocytosis+++GO:0051246///regulation of protein metabolic process+++GO:0055085///transmembrane transport 64177 64177 'Trpv6' mRNA 12 9 3 0.23 0.17 0.06 0.16 0.1 0.12 0.153333333 0.126666667 10 6 7 8 7.666666667 0.963084294 -0.059578011 04970///Salivary secretion+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034704///calcium channel complex GO:0005216///ion channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034220///ion transmembrane transport+++GO:0035898///parathyroid hormone secretion+++GO:0051289///protein homotetramerization+++GO:0051592///response to calcium ion+++GO:0055074///calcium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0098703///calcium ion import across plasma membrane 64209 64209 'Herpud1' mRNA 4107 4311 4035 124.35 128.68 129.32 108.72 112.5 109.27 127.45 110.1633333 4126 4131 4023 4151 4093.333333 0.690781961 -0.031536741 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:1990037///Lewy body core "GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0006986///response to unfolded protein+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0031396///regulation of protein ubiquitination+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045047///protein targeting to ER+++GO:1902235///regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903069///regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 64213 64213 'St7' mRNA 241 250 132 6.22 6.58 3.7 3.1 3.09 3.39 5.5 3.193333333 131 126 146 207.6666667 134.3333333 0.009655438 -0.627965524 GO:0016020///membrane+++GO:0016021///integral component of membrane 64214 64214 'Rgs18' mRNA 3 7 6 0.08 0.19 0.18 5.4 4.74 4.88 0.15 5.006666667 218 188 192 5.333333333 199.3333333 5.04E-34 5.211469518 GO:0005737///cytoplasm GO:0005096///GTPase activator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 64242 64242 'Ngb' mRNA 14 22 15 0.51 0.78 0.58 0.31 0.16 0.32 0.623333333 0.263333333 10 5 10 17 8.333333333 0.182153971 -1.039279404 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043005///neuron projection+++GO:0043204///perikaryon GO:0005344///oxygen carrier activity+++GO:0005515///protein binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0007601///visual perception+++GO:0015671///oxygen transport+++GO:0031175///neuron projection development+++GO:0043085///positive regulation of catalytic activity+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 64291 64291 'Osbpl1a' mRNA 3044.55 3182.49 2679.54 53.06 55.09 49.6 20.58 24.07 21.01 52.58333333 21.88666667 1418.51 1585.42 1376.01 2968.86 1459.98 1.10E-39 -1.031950049 GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044232///organelle membrane contact site GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0015918///sterol transport 64292 64292 'Ptges' mRNA 1280 1309 1411 19.04 19.16 22.26 36.95 36.26 35.94 20.15333333 36.38333333 2859 2740 2693 1333.333333 2764 9.81E-39 1.036954009 00590///Arachidonic acid metabolism GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0004667///prostaglandin-D synthase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0043295///glutathione binding+++GO:0050220///prostaglandin-E synthase activity GO:0001516///prostaglandin biosynthetic process+++GO:0002526///acute inflammatory response+++GO:0002544///chronic inflammatory response+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0014070///response to organic cyclic compound+++GO:0019233///sensory perception of pain+++GO:0031620///regulation of fever generation+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0034097///response to cytokine+++GO:0050727///regulation of inflammatory response+++GO:0051592///response to calcium ion 64293 64293 'Stk32b' mRNA 6 5 8 0.09 0.08 0.13 0.04 0.03 0.04 0.1 0.036666667 3 2 3 6.333333333 2.666666667 0.338041179 -1.271182658 GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction 64294 64294 'Itm2c' mRNA 16710 17169 14824 469.44 475.16 441.79 440.03 425.28 429.78 462.13 431.6966667 18008 16991 17024 16234.33333 17341 0.110479509 0.085404082 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0001540///amyloid-beta binding+++GO:0005524///ATP binding GO:0010977///negative regulation of neuron projection development+++GO:0030182///neuron differentiation+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 64295 64295 'Tmub1' mRNA 820 832 821 37.48 37.46 39.77 18.83 20.03 20.43 38.23666667 19.76333333 473 491 497 824.3333333 487 1.48E-13 -0.771187165 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055037///recycling endosome GO:0030433///ubiquitin-dependent ERAD pathway 64296 64296 'Abhd8' mRNA 2603 2487 2549 74.58 70.22 77.38 49.84 45.71 48.24 74.06 47.93 2003 1790 1874 2546.333333 1889 1.12E-09 -0.444483715 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006654///phosphatidic acid biosynthetic process+++GO:0055088///lipid homeostasis 64297 64297 'Gprc5b' mRNA 5296 5412 3926 63.48 64.26 51.06 31.89 29.67 31.69 59.6 31.08333333 2918 2766 2854 4878 2846 1.76E-21 -0.782724651 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome GO:0004930///G protein-coupled receptor activity+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007626///locomotory behavior+++GO:0010976///positive regulation of neuron projection development+++GO:0032147///activation of protein kinase activity+++GO:0042593///glucose homeostasis+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045666///positive regulation of neuron differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0050729///positive regulation of inflammatory response+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0090263///positive regulation of canonical Wnt signaling pathway 64337 64337 'Gng13' mRNA 15 10 25 3.96 2.38 6.28 4.06 3.67 4.88 4.206666667 4.203333333 17 17 22 16.66666667 18.66666667 0.863090843 0.135698043 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04742///Taste transduction+++04745///Phototransduction - fly+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0050909///sensory perception of taste 64339 64339 'Fndc4' mRNA 984 972 271 24.33 23.59 7.04 7.56 13.57 11.22 18.32 10.78333333 348 611 505 742.3333333 488 0.412208039 -0.586212109 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0050728///negative regulation of inflammatory response+++GO:0071559///response to transforming growth factor beta 64340 64340 'Dhx38' mRNA 711 693 725 8.55 8.2 9.25 9.11 8.63 8.69 8.666666667 8.81 872 807 806 709.6666667 828.3333333 0.053452399 0.209276025 03040///Spliceosome GO:0005622///intracellular+++GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000398///mRNA splicing, via spliceosome" 64378 64378 'Gpr88' mRNA 147 143 105 2.31 2.22 1.75 3.63 4.92 3.73 2.093333333 4.093333333 265 352 265 131.6666667 294 5.26E-09 1.155047275 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003774///motor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008020///G protein-coupled photoreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007602///phototransduction+++GO:0007626///locomotory behavior+++GO:0009584///detection of visible light+++GO:0019228///neuronal action potential+++GO:0050885///neuromuscular process controlling balance+++GO:0061743///motor learning+++GO:0071482///cellular response to light stimulus 64379 64379 'Irx6' mRNA 30 36 19 0.49 0.57 0.33 0.31 0.07 0.07 0.463333333 0.15 22 5 5 28.33333333 10.66666667 0.043562243 -1.422480567 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009584///detection of visible light+++GO:0010842///retina layer formation+++GO:0030182///neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0060040///retinal bipolar neuron differentiation" 64380 64380 'Ms4a4c' mRNA 72 82 82 2.43 2.64 2.93 44.85 45.73 46.46 2.666666667 45.68 1541.28 1533.11 1542.6 78.66666667 1538.996667 4.78E-241 4.278307432 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0003674///molecular_function GO:0008150///biological_process 64381 64381 'Ms4a8a' mRNA 0 1 1 0 0.06 0.06 3.34 4.41 3.56 0.04 3.77 66 85 68 0.666666667 73 1.69E-09 6.765503984 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 64383 64383 'Sirt2' mRNA 6894 7135 6859 217.61 222.42 229.78 121.2 119.78 120.68 223.27 120.5533333 4380 4239 4243 6962.666667 4287.333333 6.02E-39 -0.711783944 00760///Nicotinate and nicotinamide metabolism GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0033010///paranodal junction+++GO:0033270///paranode region of axon+++GO:0035748///myelin sheath abaxonal region+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043209///myelin sheath+++GO:0043219///lateral loop+++GO:0043220///Schmidt-Lanterman incisure+++GO:0044224///juxtaparanode region of axon+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle+++GO:0072687///meiotic spindle+++GO:0097386///glial cell projection+++GO:0097456///terminal loop+++GO:0098978///glutamatergic synapse GO:0003682///chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017136///NAD-dependent histone deacetylase activity+++GO:0033558///protein deacetylase activity+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0035035///histone acetyltransferase binding+++GO:0042826///histone deacetylase binding+++GO:0042903///tubulin deacetylase activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0046970///NAD-dependent histone deacetylase activity (H4-K16 specific)+++GO:0048487///beta-tubulin binding+++GO:0070403///NAD+ binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006476///protein deacetylation+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010507///negative regulation of autophagy+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016575///histone deacetylation+++GO:0022011///myelination in peripheral nervous system+++GO:0030154///cell differentiation+++GO:0031641///regulation of myelination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034599///cellular response to oxidative stress+++GO:0034983///peptidyl-lysine deacetylation+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043388///positive regulation of DNA binding+++GO:0043491///protein kinase B signaling+++GO:0044242///cellular lipid catabolic process+++GO:0045598///regulation of fat cell differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0051781///positive regulation of cell division+++GO:0051987///positive regulation of attachment of spindle microtubules to kinetochore+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0061433///cellular response to caloric restriction+++GO:0070446///negative regulation of oligodendrocyte progenitor proliferation+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071219///cellular response to molecule of bacterial origin+++GO:0071456///cellular response to hypoxia+++GO:0071872///cellular response to epinephrine stimulus+++GO:0090042///tubulin deacetylation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:1900195///positive regulation of oocyte maturation+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1900425///negative regulation of defense response to bacterium+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000777///positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia" 64384 64384 'Sirt3' mRNA 852 932 855 35.63 38.65 38.11 21.92 18.43 18.56 37.46333333 19.63666667 600 489 490 879.6666667 526.3333333 3.88E-12 -0.754037238 00760///Nicotinate and nicotinamide metabolism+++05230///Central carbon metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017136///NAD-dependent histone deacetylase activity+++GO:0019899///enzyme binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070403///NAD+ binding GO:0006476///protein deacetylation+++GO:0009060///aerobic respiration+++GO:0016575///histone deacetylation+++GO:0032024///positive regulation of insulin secretion+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070932///histone H3 deacetylation+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:1902553///positive regulation of catalase activity+++GO:1903109///positive regulation of mitochondrial transcription+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2000757///negative regulation of peptidyl-lysine acetylation 64385 64385 'Cyp4f14' mRNA 81 86 76 2.04 2.11 2.06 1.09 1.26 1.26 2.07 1.203333333 53 56 57 81 55.33333333 0.075373703 -0.559485567 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005504///fatty acid binding+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0018685///alkane 1-monooxygenase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050051///leukotriene-B4 20-monooxygenase activity+++GO:0050544///arachidonic acid binding+++GO:0052869///arachidonic acid omega-hydroxylase activity+++GO:0052871///alpha-tocopherol omega-hydroxylase activity+++GO:0052872///tocotrienol omega-hydroxylase activity" GO:0006690///icosanoid metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0036101///leukotriene B4 catabolic process+++GO:0042361///menaquinone catabolic process+++GO:0042376///phylloquinone catabolic process+++GO:0042377///vitamin K catabolic process+++GO:0097267///omega-hydroxylase P450 pathway 64406 64406 'Sp5' mRNA 193 146 162 5.21 3.88 4.64 2.8 2.72 2.82 4.576666667 2.78 119 113 116 167 116 0.017090928 -0.538268802 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036342///post-anal tail morphogenesis+++GO:0060349///bone morphogenesis+++GO:0071407///cellular response to organic cyclic compound 64424 64424 'Polr1e' mRNA 133 122 109 2.04 1.84 1.77 3.24 3.42 2.89 1.883333333 3.183333333 244 251 210 121.3333333 235 8.63E-07 0.94418412 03020///RNA polymerase GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex GO:0001179///RNA polymerase I transcription factor binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding "GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006351///transcription, DNA-templated+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0042790///nucleolar large rRNA transcription by RNA polymerase I" 64436 64436 'Inpp5e' mRNA 1353.04 1291.9 1386.91 18.3 17.46 19.97 10.42 10.36 9.38 18.57666667 10.05333333 889.1 864.48 774.99 1343.95 842.8566667 6.51E-13 -0.687614894 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0000139///Golgi membrane+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0042995///cell projection "GO:0003824///catalytic activity+++GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004445///inositol-polyphosphate 5-phosphatase activity+++GO:0016314///phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0106019///phosphatidylinositol-4,5-bisphosphate phosphatase activity" GO:0006629///lipid metabolic process+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016311///dephosphorylation+++GO:0017148///negative regulation of translation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:1903565///negative regulation of protein localization to cilium 64450 64450 'Gpr85' mRNA 27 37 47 0.41 0.58 0.79 0.98 0.94 0.83 0.593333333 0.916666667 72 69 60 37 67 0.027639214 0.836841282 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 64451 64451 'Dip2a' mRNA 370 369 278 2.99 2.94 2.41 2.37 1.95 2.51 2.78 2.276666667 332 269 346 339 315.6666667 0.577538552 -0.110584506 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse GO:0003987///acetate-CoA ligase activity+++GO:0005515///protein binding+++GO:0016874///ligase activity GO:0006085///acetyl-CoA biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010629///negative regulation of gene expression+++GO:0060997///dendritic spine morphogenesis+++GO:2000758///positive regulation of peptidyl-lysine acetylation 64452 64452 'Slc5a4a' mRNA 4 2 2 0.11 0.05 0.06 0 0.12 0 0.073333333 0.04 0 5 0 2.666666667 1.666666667 0.793886655 -0.664500803 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005412///glucose:sodium symporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1904659///glucose transmembrane transport 64453 64453 'Zfp280b' mRNA 834 857 650 8.78 8.86 7.51 4.42 4.01 4.72 8.383333333 4.383333333 468 416 492 780.3333333 458.6666667 6.88E-11 -0.773826053 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 64540 64540 'Tspan4' mRNA 1228.66 1120.97 1203.57 53.55 47.92 55.06 133.66 126.27 131.91 52.17666667 130.6133333 3440.92 3174.18 3295.25 1184.4 3303.45 8.00E-87 1.466707192 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle GO:0003823///antigen binding+++GO:0005178///integrin binding+++GO:0005515///protein binding GO:0065003///protein-containing complex assembly 64580 64580 'Ndst4' mRNA 7 3 4 0.07 0.03 0.04 0 0 0 0.046666667 0 0 0 0 4.666666667 0 0.024107244 -4.67527503 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0008146///sulfotransferase activity+++GO:0015016///[heparan sulfate]-glucosamine N-sulfotransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity "GO:0008152///metabolic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0030210///heparin biosynthetic process" 64602 64602 'Ireb2' mRNA 761 811 655 7.13 7.44 6.46 6.35 6.22 6.84 7.01 6.47 788 750 816 742.3333333 784.6666667 0.57782193 0.071473109 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0043025///neuronal cell body "GO:0001069///regulatory region RNA binding+++GO:0003723///RNA binding+++GO:0003994///aconitate hydratase activity+++GO:0030350///iron-responsive element binding+++GO:0030371///translation repressor activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006417///regulation of translation+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006879///cellular iron ion homeostasis+++GO:0009791///post-embryonic development+++GO:0010041///response to iron(III) ion+++GO:0010468///regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030316///osteoclast differentiation+++GO:0034101///erythrocyte homeostasis+++GO:0050892///intestinal absorption+++GO:0055072///iron ion homeostasis+++GO:0071283///cellular response to iron(III) ion+++GO:0071287///cellular response to manganese ion+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072705///cellular response to mercaptoethanol+++GO:0090650///cellular response to oxygen-glucose deprivation 64652 64652 'Nisch' mRNA 9440 9357 9062 86.4 85.7 88.19 70.37 64.67 67.62 86.76333333 67.55333333 8765 7872 8165 9286.333333 8267.333333 0.001231391 -0.180448585 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0055037///recycling endosome GO:0005178///integrin binding+++GO:0019901///protein kinase binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding "GO:0006006///glucose metabolic process+++GO:0006915///apoptotic process+++GO:0008217///regulation of blood pressure+++GO:0016601///Rac protein signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0030336///negative regulation of cell migration+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0048243///norepinephrine secretion" 64654 64654 'Fgf23' mRNA 2 2 2 0.04 0.04 0.06 0.02 0 0 0.046666667 0.006666667 1 0 0 2 0.333333333 0.371313523 -2.493392462 "04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++04928///Parathyroid hormone synthesis, secretion and action+++05200///Pathways in cancer+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity "GO:0000165///MAPK cascade+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006796///phosphate-containing compound metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0010966///regulation of phosphate transport+++GO:0010980///positive regulation of vitamin D 24-hydroxylase activity+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030500///regulation of bone mineralization+++GO:0030502///negative regulation of bone mineralization+++GO:0030643///cellular phosphate ion homeostasis+++GO:0032026///response to magnesium ion+++GO:0042359///vitamin D metabolic process+++GO:0042369///vitamin D catabolic process+++GO:0044320///cellular response to leptin stimulus+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046888///negative regulation of hormone secretion+++GO:0055062///phosphate ion homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071305///cellular response to vitamin D+++GO:0071354///cellular response to interleukin-6+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway+++GO:1904383///response to sodium phosphate" 64655 64655 'Mrps22' mRNA 311 358 319 15.67 17.81 17.05 21.86 23.18 21.29 16.84333333 22.11 498 515 469 329.3333333 494 1.15E-05 0.574261611 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0008150///biological_process 64656 64656 'Mrps23' mRNA 545 566 584 24.28 25.03 27.58 26.08 27.26 29.23 25.63 27.52333333 668 681 726 565 691.6666667 0.018320888 0.2788852 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0031965///nuclear membrane GO:0003735///structural constituent of ribosome GO:0006412///translation 64657 64657 'Mrps10' mRNA 777.87 759.62 728.68 39.39 40.34 39.91 43.32 45.6 41.98 39.88 43.63333333 906.79 956.51 840.72 755.39 901.34 0.019550306 0.244203816 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 64658 64658 'Mrps25' mRNA 1174.35 1156.35 1198.93 10.25 9.92 11.1 10.62 10.75 9.93 10.42333333 10.43333333 1401.39 1385.63 1268.32 1176.543333 1351.78 0.047605975 0.187140898 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0032543///mitochondrial translation 64659 64659 'Mrps14' mRNA 1450 1414 1334 40.91 39.3 39.94 40.94 42.54 42.33 40.05 41.93666667 1668 1693 1670 1399.333333 1677 0.001207019 0.250413469 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0031965///nuclear membrane GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0006412///translation+++GO:0032543///mitochondrial translation 64660 64660 'Mrps24' mRNA 953 921 803 60.2 57.51 53.8 54.23 59.63 65.73 57.17 59.86333333 984 1055 1153 892.3333333 1064 0.019550051 0.245637065 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0032543///mitochondrial translation 64685 64685 'Nmi' mRNA 332 400 366 15.08 18.31 17.47 23.39 25.83 25.39 16.95333333 24.87 612 647 637 366 632 2.85E-10 0.776917346 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0032480///negative regulation of type I interferon production+++GO:0032687///negative regulation of interferon-alpha production+++GO:0032688///negative regulation of interferon-beta production+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0050729///positive regulation of inflammatory response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902524///positive regulation of protein K48-linked ubiquitination" 64704 64704 'Htra2' mRNA 742.45 752.62 695 24.94 24.92 24.77 30.79 29.24 28.8 24.87666667 29.61 1053.19 976.42 953.49 730.0233333 994.3666667 2.79E-06 0.434539042 04210///Apoptosis+++04214///Apoptosis - fly+++04215///Apoptosis - multiple species+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0035631///CD40 receptor complex+++GO:1905370///serine-type endopeptidase complex GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0006672///ceramide metabolic process+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0007568///aging+++GO:0007628///adult walking behavior+++GO:0008344///adult locomotory behavior+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009635///response to herbicide+++GO:0010822///positive regulation of mitochondrion organization+++GO:0012501///programmed cell death+++GO:0019742///pentacyclic triterpenoid metabolic process+++GO:0030900///forebrain development+++GO:0034599///cellular response to oxidative stress+++GO:0034605///cellular response to heat+++GO:0035458///cellular response to interferon-beta+++GO:0040014///regulation of multicellular organism growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044257///cellular protein catabolic process+++GO:0048666///neuron development+++GO:0060548///negative regulation of cell death+++GO:0071300///cellular response to retinoic acid+++GO:0071363///cellular response to growth factor stimulus+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1904924///negative regulation of mitophagy in response to mitochondrial depolarization+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 64705 64705 'Dpys' mRNA 26 24 27 0.7 0.63 0.77 0.05 0.09 0.09 0.7 0.076666667 2 4 4 25.66666667 3.333333333 9.37E-05 -2.956683004 00240///Pyrimidine metabolism+++00410///beta-Alanine metabolism+++00770///Pantothenate and CoA biosynthesis+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex "GO:0002058///uracil binding+++GO:0002059///thymine binding+++GO:0004157///dihydropyrimidinase activity+++GO:0008270///zinc ion binding+++GO:0016597///amino acid binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding" GO:0006208///pyrimidine nucleobase catabolic process+++GO:0006210///thymine catabolic process+++GO:0006212///uracil catabolic process+++GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0019482///beta-alanine metabolic process+++GO:0019860///uracil metabolic process+++GO:0046050///UMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process 64706 64706 'Scube1' mRNA 63 75 68 0.81 0.69 0.74 1.97 1.71 1.94 0.746666667 1.873333333 215 180 195 68.66666667 196.6666667 7.38E-12 1.505331299 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0045880///positive regulation of smoothened signaling pathway 64707 64707 'Suv39h2' mRNA 48.1 42.71 21.7 0.71 0.6 0.33 0.35 0.32 0.29 0.546666667 0.32 26.52 22.37 24.15 37.50333333 24.34666667 0.238608309 -0.624379521 00310///Lysine degradation "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:1904047///S-adenosyl-L-methionine binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006338///chromatin remodeling+++GO:0007049///cell cycle+++GO:0007140///male meiotic nuclear division+++GO:0030154///cell differentiation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0036123///histone H3-K9 dimethylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0042754///negative regulation of circadian rhythm+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0051567///histone H3-K9 methylation+++GO:0071456///cellular response to hypoxia" 64817 64817 'Svep1' mRNA 44 52 42 0.2 0.24 0.21 0.7 0.6 0.69 0.216666667 0.663333333 173 147 167 46 162.3333333 4.47E-13 1.808609194 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031012///extracellular matrix GO:0003682///chromatin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001945///lymph vessel development+++GO:0003017///lymph circulation+++GO:0007155///cell adhesion+++GO:0008544///epidermis development+++GO:0010467///gene expression+++GO:0016477///cell migration+++GO:0036303///lymph vessel morphogenesis+++GO:0048014///Tie signaling pathway+++GO:0090136///epithelial cell-cell adhesion+++GO:0120193///tight junction organization 64833 64833 'Acot10' mRNA 0 0 1 0 0 0.04 0 0.07 0 0.013333333 0.023333333 0 2 0 0.333333333 0.666666667 0.863090843 0.906589207 GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006637///acyl-CoA metabolic process 64898 64898 'Lpin2' mRNA 4154 4148 3898 31.82 31.46 31.09 9.98 8.44 10.82 31.45666667 9.746666667 1495 1244 1508.02 4066.666667 1415.673333 1.52E-96 -1.534688675 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04150///mTOR signaling pathway+++04936///Alcoholic liver disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003713///transcription coactivator activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0016311///dephosphorylation+++GO:0019432///triglyceride biosynthetic process+++GO:0032869///cellular response to insulin stimulus+++GO:0044255///cellular lipid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II 64899 64899 'Lpin3' mRNA 184 188 169 2.93 2.95 2.87 4.09 4.6 4.56 2.916666667 4.416666667 297 324 320 180.3333333 313.6666667 9.15E-07 0.789105664 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04150///mTOR signaling pathway+++04936///Alcoholic liver disease GO:0005634///nucleus GO:0003713///transcription coactivator activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0016311///dephosphorylation+++GO:0019432///triglyceride biosynthetic process+++GO:0032869///cellular response to insulin stimulus+++GO:0044255///cellular lipid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II 64918 64918 'Bhmt2' mRNA 103 106 123 2.79 2.83 3.54 1.53 0.75 0.54 3.053333333 0.94 65 31 22 110.6666667 39.33333333 3.07E-05 -1.516545141 00270///Cysteine and methionine metabolism GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008898///S-adenosylmethionine-homocysteine S-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0047150///betaine-homocysteine S-methyltransferase activity+++GO:0061627///S-methylmethionine-homocysteine S-methyltransferase activity GO:0009086///methionine biosynthetic process+++GO:0032259///methylation+++GO:0033477///S-methylmethionine metabolic process+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0071267///L-methionine salvage 64929 64929 'Scel' mRNA 48 52 60 0.86 0.88 1.19 0.45 0.45 0.44 0.976666667 0.446666667 29 29 28 53.33333333 28.66666667 0.023893206 -0.911856008 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0046872///metal ion binding GO:0008544///epidermis development+++GO:0009612///response to mechanical stimulus+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0030216///keratinocyte differentiation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 64930 64930 'Tsc1' mRNA 896 970 956 6.17 6.58 7 5.27 4.72 5.38 6.583333333 5.123333333 882 772 869 940.6666667 841 0.106077443 -0.175266569 04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04218///Cellular senescence+++04714///Thermogenesis+++04910///Insulin signaling pathway+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05168///Herpes simplex virus 1 infection+++05231///Choline metabolism in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0033596///TSC1-TSC2 complex+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0101031///chaperone complex GO:0005515///protein binding+++GO:0030544///Hsp70 protein binding+++GO:0032794///GTPase activating protein binding+++GO:0042030///ATPase inhibitor activity+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002250///adaptive immune response+++GO:0006407///rRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0006813///potassium ion transport+++GO:0007160///cell-matrix adhesion+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0009790///embryo development+++GO:0010977///negative regulation of neuron projection development+++GO:0016239///positive regulation of macroautophagy+++GO:0016242///negative regulation of macroautophagy+++GO:0017148///negative regulation of translation+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030030///cell projection organization+++GO:0031667///response to nutrient levels+++GO:0032007///negative regulation of TOR signaling+++GO:0032780///negative regulation of ATPase activity+++GO:0032868///response to insulin+++GO:0034260///negative regulation of GTPase activity+++GO:0042552///myelination+++GO:0043379///memory T cell differentiation+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0045792///negative regulation of cell size+++GO:0045859///regulation of protein kinase activity+++GO:0046323///glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0051492///regulation of stress fiber assembly+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051726///regulation of cell cycle+++GO:0051893///regulation of focal adhesion assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0055007///cardiac muscle cell differentiation+++GO:0090630///activation of GTPase activity+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:1901214///regulation of neuron death+++GO:1901652///response to peptide+++GO:1903204///negative regulation of oxidative stress-induced neuron death 64931 64931 'Izumo1r' mRNA 8 5 2 0.5 0.32 0.09 3.35 3.1 3.64 0.303333333 3.363333333 71 70 76 5 72.33333333 3.41E-13 3.850040137 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005542///folic acid binding+++GO:0038023///signaling receptor activity GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0035036///sperm-egg recognition 64933 64933 'Ap3m2' mRNA 2389 2449 2510 38.17 38.47 42.54 12.46 11.8 12.22 39.72666667 12.16 898 829 852 2449.333333 859.6666667 7.61E-82 -1.524587139 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030131///clathrin adaptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1904115///axon cytoplasm GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048490///anterograde synaptic vesicle transport 64934 64934 'Pes1' mRNA 1117 1053 1042 21.12 19.6 20.9 22.95 24.72 23.39 20.54 23.68666667 1396 1469 1378 1070.666667 1414.333333 5.45E-06 0.390381636 "GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex" GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0007000///nucleolus organization+++GO:0008283///cell proliferation+++GO:0033365///protein localization to organelle+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0051726///regulation of cell cycle" 64945 64945 'Cldn12' mRNA 1250 1307 1292 18.31 18.52 19.88 13.83 12.99 13.16 18.90333333 13.32666667 1099 1006 1001 1283 1035.333333 2.69E-04 -0.322776732 GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0070160///tight junction+++GO:0071944///cell periphery GO:0042802///identical protein binding GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0120192///tight junction assembly 65019 65019 'Rpl23' mRNA 2146 2064 2185 127.36 121.08 137.6 177.75 190.08 192.9 128.68 186.91 3435 3581 3603 2131.666667 3539.666667 8.33E-23 0.718632423 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex GO:0001223///transcription coactivator binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0070180///large ribosomal subunit rRNA binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0032986///protein-DNA complex disassembly+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071158///positive regulation of cell cycle arrest+++GO:0072717///cellular response to actinomycin D+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 65020 65020 'Zfp110' mRNA 1431 1496 1438 21.73 22.39 23.36 14.33 14.74 13.62 22.49333333 14.23 1091 1086 1006 1455 1061 2.13E-08 -0.467668307 04722///Neurotrophin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0046328///regulation of JNK cascade+++GO:0051402///neuron apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1900112///regulation of histone H3-K9 trimethylation+++GO:1990009///retinal cell apoptotic process" 65079 65079 'Rtn4r' mRNA 2 2 3 0.06 0.06 0.09 0.33 0.13 0.37 0.07 0.276666667 13 5 14 2.333333333 10.66666667 0.052465276 2.169668565 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0044295///axonal growth cone+++GO:0045121///membrane raft+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0035374///chondroitin sulfate binding+++GO:0038023///signaling receptor activity+++GO:0038131///neuregulin receptor activity+++GO:0044877///protein-containing complex binding+++GO:0048495///Roundabout binding+++GO:1905573///ganglioside GM1 binding+++GO:1905576///ganglioside GT1b binding GO:0007166///cell surface receptor signaling pathway+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0010977///negative regulation of neuron projection development+++GO:0022038///corpus callosum development+++GO:0023041///neuronal signal transduction+++GO:0030517///negative regulation of axon extension+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048681///negative regulation of axon regeneration+++GO:0050919///negative chemotaxis 65086 65086 'Lpar3' mRNA 900 922 873 20.11 20.28 20.69 6.72 6.49 6.3 20.36 6.503333333 346 326 314 898.3333333 328.6666667 1.73E-43 -1.462568674 04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++05200///Pathways in cancer GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0001965///G-protein alpha-subunit binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005543///phospholipid binding+++GO:0070915///lysophosphatidic acid receptor activity GO:0000187///activation of MAPK activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0010467///gene expression+++GO:0019222///regulation of metabolic process+++GO:0032060///bleb assembly+++GO:0043410///positive regulation of MAPK cascade+++GO:0048672///positive regulation of collateral sprouting+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0051928///positive regulation of calcium ion transport 65098 65098 'Zfand6' mRNA 2749 2881 1747 99.66 103.38 67.69 65.84 89.8 80.37 90.24333333 78.67 2062 2762 2466 2459 2430 0.967164942 -0.014830692 GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding GO:0006625///protein targeting to peroxisome+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0071356///cellular response to tumor necrosis factor 65099 65099 'Irak1bp1' mRNA 333.9 370 319 10.12 11.04 10.25 5.07 6.5 5.74 10.47 5.77 192 240.96 211 340.9666667 214.6533333 2.92E-05 -0.676787858 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0006955///immune response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling 65100 65100 'Zic5' mRNA 163 168 160 3.84 3.88 3.99 3.13 2.82 2.7 3.903333333 2.883333333 153 135 128 163.6666667 138.6666667 0.272114125 -0.251789587 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001843///neural tube closure+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0045893///positive regulation of transcription, DNA-templated" 65102 65102 'Nif3l1' mRNA 595.38 645.76 604.14 14.89 16.25 17.32 16.7 18.08 17.85 16.15333333 17.54333333 680.09 661.13 680.95 615.0933333 674.0566667 0.322336764 0.12055575 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding "GO:0030182///neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1903507///negative regulation of nucleic acid-templated transcription" 65103 65103 'Arl6ip6' mRNA 311 352 343 6.77 7.55 7.93 7.54 7.7 7.73 7.416666667 7.656666667 398 397 395 335.3333333 396.6666667 0.125684601 0.229708895 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process 65105 65105 'Arl6ip4' mRNA 969 992 967 50.5 51.06 53.47 48.96 49.88 49.74 51.67666667 49.52666667 1078 1071 1059 976 1069.333333 0.227947484 0.119746893 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0005515///protein binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing 65106 65106 'Arl6ip5' mRNA 3027 3264 2586 136.06 144.8 123.32 141.72 135.72 138.11 134.7266667 138.5166667 3620 3382 3412 2959 3471.333333 0.001841719 0.222080342 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008022///protein C-terminus binding GO:0002037///negative regulation of L-glutamate import across plasma membrane+++GO:0006749///glutathione metabolic process+++GO:0007611///learning or memory+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0015031///protein transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0036475///neuron death in response to oxidative stress+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051051///negative regulation of transport+++GO:0051580///regulation of neurotransmitter uptake+++GO:0071407///cellular response to organic cyclic compound+++GO:0072659///protein localization to plasma membrane+++GO:0098712///L-glutamate import across plasma membrane 65107 65107 'Lrp10' mRNA 6364 6528 2062 115.67 116.77 39.86 40.54 79.29 70.65 90.76666667 63.49333333 2561 4895 4327 4984.666667 3927.666667 0.663495683 -0.325721779 GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005041///low-density lipoprotein particle receptor activity GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0006897///endocytosis+++GO:0048839///inner ear development 65111 65111 'Dap3' mRNA 1350 1298 1144 50.53 47.76 44.83 45.09 42.42 42.63 47.70666667 43.38 1358 1253 1257 1264 1289.333333 0.863090843 0.018583716 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005761///mitochondrial ribosome+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006915///apoptotic process+++GO:0008637///apoptotic mitochondrial changes 65112 65112 'Pmepa1' mRNA 420 403 435 4.96 4.67 5.44 10.19 8.68 10.03 5.023333333 9.633333333 991 825 946 419.3333333 920.6666667 1.34E-23 1.11968897 GO:0000139///Golgi membrane+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0008278///cohesin complex+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097431///mitotic spindle pole GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0070412///R-SMAD binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0009968///negative regulation of signal transduction+++GO:0010991///negative regulation of SMAD protein complex assembly+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0051301///cell division+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0090307///mitotic spindle assembly 65113 65113 'Ndfip1' mRNA 13992 14699 14710 448.96 464.86 500.76 351.12 363.09 352.41 471.5266667 355.54 12576 12694 12216 14467 12495.33333 2.43E-04 -0.224499959 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030173///integral component of Golgi membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0050699///WW domain binding GO:0002761///regulation of myeloid leukocyte differentiation+++GO:0002829///negative regulation of type 2 immune response+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006879///cellular iron ion homeostasis+++GO:0007034///vacuolar transport+++GO:0010629///negative regulation of gene expression+++GO:0030001///metal ion transport+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032410///negative regulation of transporter activity+++GO:0032713///negative regulation of interleukin-4 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0045619///regulation of lymphocyte differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0048294///negative regulation of isotype switching to IgE isotypes+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0050728///negative regulation of inflammatory response+++GO:0051224///negative regulation of protein transport 65114 65114 'Vps35' mRNA 3212 3135 3341 54.97 52.79 60.65 61.44 61.62 62.2 56.13666667 61.75333333 4131 4047 4050 3229.333333 4076 5.17E-06 0.321840661 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030904///retromer complex+++GO:0030906///retromer, cargo-selective complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097422///tubular endosome+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099073///mitochondrion-derived vesicle" GO:0005515///protein binding+++GO:0031748///D1 dopamine receptor binding "GO:0006624///vacuolar protein processing+++GO:0006886///intracellular protein transport+++GO:0007040///lysosome organization+++GO:0007416///synapse assembly+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010821///regulation of mitochondrion organization+++GO:0015031///protein transport+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0032268///regulation of cellular protein metabolic process+++GO:0032456///endocytic recycling+++GO:0032463///negative regulation of protein homooligomerization+++GO:0033365///protein localization to organelle+++GO:0036010///protein localization to endosome+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0045056///transcytosis+++GO:0050728///negative regulation of inflammatory response+++GO:0050882///voluntary musculoskeletal movement+++GO:0060161///positive regulation of dopamine receptor signaling pathway+++GO:0060548///negative regulation of cell death+++GO:0061357///positive regulation of Wnt protein secretion+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090326///positive regulation of locomotion involved in locomotory behavior+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0099074///mitochondrion to lysosome transport+++GO:0099639///neurotransmitter receptor transport, endosome to plasma membrane+++GO:1901215///negative regulation of neuron death+++GO:1902823///negative regulation of late endosome to lysosome transport+++GO:1902950///regulation of dendritic spine maintenance+++GO:1903181///positive regulation of dopamine biosynthetic process+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1903828///negative regulation of cellular protein localization+++GO:1905166///negative regulation of lysosomal protein catabolic process+++GO:2000331///regulation of terminal button organization" 65115 65115 'Bean1' mRNA 8 4 0 0.17 0.11 0 0.17 0.28 0.37 0.093333333 0.273333333 9 12 19 4 13.33333333 0.096038776 1.752213728 05017///Spinocerebellar ataxia GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process 65116 65116 'Prrg2' mRNA 377 427 357 17.06 19.05 17.09 20.39 19.09 20.82 17.73333333 20.1 524 476 510 387 503.3333333 0.003811386 0.36897549 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0008150///biological_process 65221 65221 'Slc15a3' mRNA 32 19 28 0.76 0.45 0.71 13.77 12.36 13.03 0.64 13.05333333 663 581 607 26.33333333 617 2.66E-102 4.537048847 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0015293///symporter activity+++GO:0015647///peptidoglycan transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0071916///dipeptide transmembrane transporter activity GO:0002376///immune system process+++GO:0006857///oligopeptide transport+++GO:0015031///protein transport+++GO:0015833///peptide transport+++GO:0015835///peptidoglycan transport+++GO:0045087///innate immune response+++GO:0055085///transmembrane transport+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0140206///dipeptide import across plasma membrane 65246 65246 'Xpo7' mRNA 897.33 990.48 824.22 9.22 10.05 8.93 7.11 8.19 6.84 9.4 7.38 789 866.92 721.66 904.01 792.5266667 0.082169335 -0.198783344 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm GO:0005049///nuclear export signal receptor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051168///nuclear export+++GO:0051169///nuclear transport 65247 65247 'Asb1' mRNA 642 719 623 5.85 6.46 6.04 2.29 2.44 2.02 6.116666667 2.25 290 303 252 661.3333333 281.6666667 2.75E-23 -1.241440054 GO:0000151///ubiquitin ligase complex GO:0061630///ubiquitin protein ligase activity GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0030539///male genitalia development+++GO:0035556///intracellular signal transduction 65254 65254 'Dpysl5' mRNA 267 265 280 2.8 2.73 3.2 1.38 1.14 0.88 2.91 1.133333333 154 125 92 270.6666667 123.6666667 1.90E-08 -1.146221614 04360///Axon guidance GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body "GO:0004157///dihydropyrimidinase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds" GO:0006208///pyrimidine nucleobase catabolic process+++GO:0007399///nervous system development+++GO:0007411///axon guidance 65255 65255 'Asb4' mRNA 8 19 16 0.13 0.31 0.28 0.49 0.74 0.64 0.24 0.623333333 36 52 43 14.33333333 43.66666667 0.001721764 1.597160506 GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0051865///protein autoubiquitination+++GO:2001214///positive regulation of vasculogenesis 65256 65256 'Asb2' mRNA 67 36 27 1.46 0.85 0.62 0.77 0.52 0.67 0.976666667 0.653333333 39 24 32 43.33333333 31.66666667 0.389759018 -0.458050069 GO:0000151///ubiquitin ligase complex+++GO:0030018///Z disc+++GO:0031466///Cul5-RING ubiquitin ligase complex GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097602///cullin family protein binding GO:0000209///protein polyubiquitination+++GO:0001947///heart looping+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0014732///skeletal muscle atrophy+++GO:0016567///protein ubiquitination+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction+++GO:0035914///skeletal muscle cell differentiation+++GO:0036336///dendritic cell migration+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045445///myoblast differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:0055013///cardiac muscle cell development+++GO:0071800///podosome assembly 65257 65257 'Asb3' mRNA 517 503 535 13.43 12.66 13.92 7.68 8.02 10.24 13.33666667 8.646666667 340 342 441 518.3333333 374.3333333 9.95E-04 -0.482599128 GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 652925 652925 'Tmem243' mRNA 34 29 22 2.21 1.86 1.52 2.89 2.03 2.81 1.863333333 2.576666667 51 35 48 28.33333333 44.66666667 0.155484427 0.647882827 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 653016 653016 'Mymx' mRNA 5 2 3 0.42 0.17 0.27 0 0.15 0 0.286666667 0.05 0 2 0 3.333333333 0.666666667 0.300960807 -2.320012847 GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007517///muscle organ development+++GO:0007520///myoblast fusion+++GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045026///plasma membrane fusion+++GO:0060538///skeletal muscle organ development 654309 654309 'Nrp' mRNA 104.28 92.77 80.07 5.5 4.83 4.48 3.75 3.27 3.84 4.936666667 3.62 81.53 69.25 80.81 92.37333333 77.19666667 0.387670372 -0.272635408 654459 654459 'Defb25' mRNA 176 183 244 88.2 94.08 131.03 12.67 9.36 7.56 104.4366667 9.863333333 28 20 16 201 21.33333333 5.80E-27 -3.258443824 GO:0005576///extracellular region GO:0003674///molecular_function GO:0006952///defense response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0032722///positive regulation of chemokine production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0071224///cellular response to peptidoglycan+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 654462 654462 'Kncn' mRNA 1922 1954 1806 146.81 147.82 146.39 11.07 10.41 10.64 147.0066667 10.70666667 166 152 154 1894 157.3333333 9.49E-270 -3.600886982 GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0032437///cuticular plate+++GO:0036064///ciliary basal body+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell+++GO:0060091///kinocilium GO:0003674///molecular_function GO:0008150///biological_process 654470 654470 'Tctn1' mRNA 398.71 422.11 463.37 5.28 5.5 6.51 4.13 3.98 4.25 5.763333333 4.12 359.14 338.08 357.64 428.0633333 351.62 0.044090009 -0.298995184 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection GO:0003674///molecular_function+++GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0001841///neural tube formation+++GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0008589///regulation of smoothened signaling pathway+++GO:0021523///somatic motor neuron differentiation+++GO:0021537///telencephalon development+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0021956///central nervous system interneuron axonogenesis+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:1904491///protein localization to ciliary transition zone 654498 654498 'Hhla1' mRNA 30 40 33 0.75 0.98 0.87 0.82 1.02 1.23 0.866666667 1.023333333 38 46 55 34.33333333 46.33333333 0.354202939 0.424128629 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 654795 654795 'Sdr39u1' mRNA 1650.8 1795.06 1753.41 75.23 81.72 85.63 46.14 47.77 45.61 80.86 46.50666667 1189.49 1176.31 1111.55 1733.09 1159.116667 7.33E-13 -0.593374739 GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity GO:0008150///biological_process 654801 654801 'Zfp784' mRNA 502 479 440 13.22 12.42 12.29 7.1 6.26 5.92 12.64333333 6.426666667 310 267 250 473.6666667 275.6666667 5.42E-09 -0.792509936 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II 654812 654812 'Angptl7' mRNA 15 16 7 0.41 0.43 0.2 1.15 1.15 1.16 0.346666667 1.153333333 48 47 47 12.66666667 47.33333333 9.41E-05 1.900257634 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:1901346///negative regulation of vasculature development involved in avascular cornea development in camera-type eye+++GO:1903053///regulation of extracellular matrix organization 654818 654818 'Smco3' mRNA 380.79 409.77 375.86 10.54 11.17 11.03 8.06 8 7.35 10.91333333 7.803333333 334.77 324.59 295.75 388.8066667 318.37 0.038226304 -0.29999389 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 654821 654821 'Gcnt7' mRNA 244.84 197.5 204.25 2.91 2.17 2.25 2.42 2.23 2.17 2.443333333 2.273333333 254.58 229.36 251.89 215.53 245.2766667 0.387587796 0.174506439 GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0008150///biological_process 654824 654824 'Ankrd37' mRNA 286 329 289 18.95 21.67 20.08 6.01 6.8 4.8 20.23333333 5.87 102 114 80 301.3333333 98.66666667 1.82E-17 -1.621026333 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0005515///protein binding GO:0008150///biological_process 65945 65945 'Clstn1' mRNA 6325 6612 4975 78.37 80.39 65.69 42.86 38.84 42.63 74.81666667 41.44333333 3937 3485 3797 5970.666667 3739.666667 1.28E-19 -0.681981405 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098845///postsynaptic endosome+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:0099065///integral component of spine apparatus membrane GO:0001540///amyloid-beta binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0042988///X11-like protein binding GO:0001558///regulation of cell growth+++GO:0006874///cellular calcium ion homeostasis+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007268///chemical synaptic transmission+++GO:0050806///positive regulation of synaptic transmission+++GO:0051965///positive regulation of synapse assembly+++GO:0090128///regulation of synapse maturation+++GO:0098969///neurotransmitter receptor transport to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse 65960 65960 'Twsg1' mRNA 8153 8472 5884 108.72 111.12 83.22 86.53 87.29 89.99 101.02 87.93666667 7470 7362 7525 7503 7452.333333 0.903250008 -0.013742109 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0050431///transforming growth factor beta binding "GO:0001503///ossification+++GO:0001707///mesoderm formation+++GO:0001818///negative regulation of cytokine production+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007435///salivary gland morphogenesis+++GO:0009790///embryo development+++GO:0009888///tissue development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0030510///regulation of BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030900///forebrain development+++GO:0043010///camera-type eye development+++GO:0045668///negative regulation of osteoblast differentiation+++GO:2000515///negative regulation of CD4-positive, alpha-beta T cell activation+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation" 65961 65961 'Utp3' mRNA 683 697 693 24.48 24.63 26.35 33.32 29.7 33.89 25.15333333 32.30333333 1068 929 1051 691 1016 3.07E-08 0.542796234 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome GO:0005515///protein binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006325///chromatin organization+++GO:0007275///multicellular organism development+++GO:0007420///brain development" 65962 65962 'Slc9a3r2' mRNA 2605 2671 2441 77.41 78.5 76.43 41.88 40.83 43.17 77.44666667 41.96 1714 1636 1731 2572.333333 1693.666667 9.28E-21 -0.613810722 04960///Aldosterone-regulated sodium reabsorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032991///protein-containing complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0019902///phosphatase binding+++GO:0042802///identical protein binding+++GO:0043495///protein membrane anchor+++GO:0047485///protein N-terminus binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0060090///molecular adaptor activity GO:0007605///sensory perception of sound+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0034767///positive regulation of ion transmembrane transport+++GO:0072659///protein localization to plasma membrane 65963 65963 'Tmem176b' mRNA 28752 29794 28055 1541.23 1578.6 1596.59 2439.46 2404.97 2441.24 1572.14 2428.556667 51814 49761 50113 28867 50562.66667 8.68E-73 0.796822662 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0005515///protein binding GO:0030154///cell differentiation+++GO:2001199///negative regulation of dendritic cell differentiation 65964 65964 'Map3k20' mRNA 1108 1191 1063 13.31 14.58 13.41 11.22 9.09 11.91 13.76666667 10.74 1301 1093 1338.95 1120.666667 1244.316667 0.185862089 0.139022457 04010///MAPK signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0000077///DNA damage checkpoint+++GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0038066///p38MAPK cascade+++GO:0042733///embryonic digit morphogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0051403///stress-activated MAPK cascade+++GO:0051726///regulation of cell cycle+++GO:0060173///limb development+++GO:0071480///cellular response to gamma radiation+++GO:1904291///positive regulation of mitotic DNA damage checkpoint 65967 65967 'Eefsec' mRNA 812 865 738 18.95 19.65 18.56 12.53 13.79 14.42 19.05333333 13.58 637 639 676 805 650.6666667 0.002246741 -0.316327682 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003746///translation elongation factor activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding GO:0001514///selenocysteine incorporation+++GO:0006412///translation+++GO:0006414///translational elongation 65969 65969 'Cubn' mRNA 16 10 10 0.07 0.05 0.05 0.1 0.12 0.13 0.056666667 0.116666667 26 30 31 12 29 0.029542766 1.265558049 04977///Vitamin digestion and absorption GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030135///coated vesicle+++GO:0030139///endocytic vesicle+++GO:0030666///endocytic vesicle membrane+++GO:0031526///brush border membrane+++GO:0032991///protein-containing complex+++GO:0043202///lysosomal lumen+++GO:0043235///receptor complex+++GO:0045177///apical part of cell+++GO:0070062///extracellular exosome GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030492///hemoglobin binding+++GO:0031419///cobalamin binding+++GO:0038023///signaling receptor activity+++GO:0038024///cargo receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0006629///lipid metabolic process+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007584///response to nutrient+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009235///cobalamin metabolic process+++GO:0009617///response to bacterium+++GO:0015031///protein transport+++GO:0015889///cobalamin transport+++GO:0020028///endocytic hemoglobin import+++GO:0042366///cobalamin catabolic process+++GO:0042953///lipoprotein transport 65970 65970 'Lima1' mRNA 3222 3253 3165 41.28 42.3 42.94 46.54 42.46 46.19 42.17333333 45.06333333 3987 3658 3905 3213.333333 3850 8.19E-05 0.248174085 GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0032154///cleavage furrow+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016477///cell migration+++GO:0030299///intestinal cholesterol absorption+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0031529///ruffle organization+++GO:0042632///cholesterol homeostasis+++GO:0051017///actin filament bundle assembly 65971 65971 'Tbata' mRNA 15 18 7 0.76 0.8 0.36 0.31 0.44 0.23 0.64 0.326666667 8 12 4 13.33333333 8 0.439147393 -0.730804298 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0036064///ciliary basal body GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0048515///spermatid differentiation 65972 65972 'Ifi30' mRNA 760 719 835 49.77 46.57 58.02 286.08 271.2 287.3 51.45333333 281.5266667 5008 4627 4860 771.3333333 4831.666667 7.29E-233 2.631555894 04612///Antigen processing and presentation GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle "GO:0015036///disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor" GO:0002376///immune system process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050821///protein stabilization 65973 65973 'Asph' mRNA 1764.55 2012.3 1933.09 29.03 32.36 33.79 27.75 25.81 26.66 31.72666667 26.74 1986.66 1827 1876.59 1903.313333 1896.75 0.863090843 -0.018461007 04020///Calcium signaling pathway+++04260///Cardiac muscle contraction GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032541///cortical endoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane GO:0004597///peptide-aspartate beta-dioxygenase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity "GO:0007389///pattern specification process+++GO:0008285///negative regulation of cell proliferation+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0018193///peptidyl-amino acid modification+++GO:0031585///regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0031647///regulation of protein stability+++GO:0032237///activation of store-operated calcium channel activity+++GO:0033198///response to ATP+++GO:0035108///limb morphogenesis+++GO:0042264///peptidyl-aspartic acid hydroxylation+++GO:0045862///positive regulation of proteolysis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0055074///calcium ion homeostasis+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0090316///positive regulation of intracellular protein transport+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:1901879///regulation of protein depolymerization" 66011 66011 'Ranbp17' mRNA 156 188 105 1.29 1.48 0.85 0.54 0.68 0.75 1.206666667 0.656666667 62 67 80 149.6666667 69.66666667 4.24E-05 -1.103748488 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm GO:0005049///nuclear export signal receptor activity+++GO:0031267///small GTPase binding GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051168///nuclear export+++GO:0051169///nuclear transport 66039 66039 'Tmem254a' mRNA 1946 1926 1856 70.21 65.98 71.99 44.77 46.18 44.19 69.39333333 45.04666667 1554 1591 1507 1909.333333 1550.666667 3.23E-05 -0.311545593 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66042 66042 'Sostdc1' mRNA 406 462 415 13.41 15.04 14.54 24.03 24.26 25.19 14.33 24.49333333 836 824 848 427.6666667 836 1.33E-19 0.956049316 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005515///protein binding+++GO:0036122///BMP binding+++GO:0098821///BMP receptor activity GO:0007389///pattern specification process+++GO:0010454///negative regulation of cell fate commitment+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030509///BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031069///hair follicle morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0045662///negative regulation of myoblast differentiation+++GO:0060648///mammary gland bud morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000016///negative regulation of determination of dorsal identity 66043 66043 'Atp5d' mRNA 6323 6100 6072 441.35 421.44 449.68 427.06 429.98 431.21 437.49 429.4166667 7008 6876 6836 6165 6906.666667 0.010168312 0.151582983 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0045259///proton-transporting ATP synthase complex+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0009060///aerobic respiration+++GO:0015986///ATP synthesis coupled proton transport+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process+++GO:1902600///proton transmembrane transport 66044 66044 'Dtd1' mRNA 876 808 849 41.41 37.7 42.58 21.33 22.37 21.33 40.56333333 21.67666667 518 530 501 844.3333333 516.3333333 9.73E-12 -0.722258983 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004821///histidine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051499///D-aminoacyl-tRNA deacylase activity+++GO:0051500///D-tyrosyl-tRNA(Tyr) deacylase activity GO:0006260///DNA replication+++GO:0006399///tRNA metabolic process+++GO:0006412///translation+++GO:0006427///histidyl-tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 66046 66046 'Ndufb5' mRNA 1864 2058 1860 143.74 156.32 150.77 140.11 151.54 142.4 150.2766667 144.6833333 2116 2188 2055 1927.333333 2119.666667 0.1206869 0.126557614 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 66047 66047 'Mrpl54' mRNA 841 848 802 110.75 111.25 112.11 105.77 128.82 112.42 111.37 115.67 916 1084 938 830.3333333 979.3333333 0.03890289 0.228298556 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0008150///biological_process 66048 66048 'Emc6' mRNA 928 996 918 41.18 43.62 43.22 48.26 46.28 45.38 42.67333333 46.64 1249 1168 1135 947.3333333 1184 4.62E-04 0.309949096 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex+++GO:0097631///integral component of omegasome membrane GO:0032977///membrane insertase activity GO:0000045///autophagosome assembly+++GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 66049 66049 'Rogdi' mRNA 2628 2618 2470 113.88 111.34 112.57 64.61 66.42 65.95 112.5966667 65.66 1717 1711 1700 2572 1709.333333 7.07E-20 -0.60056748 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0043291///RAVE complex+++GO:0045202///synapse+++GO:0098793///presynapse GO:0003674///molecular_function GO:0007420///brain development+++GO:0008284///positive regulation of cell proliferation+++GO:0022008///neurogenesis+++GO:0030097///hemopoiesis+++GO:0042475///odontogenesis of dentin-containing tooth 66050 66050 '0610009B22Rik' mRNA 607 622 598 52.03 52.57 54.1 46.65 49.46 49.74 52.9 48.61666667 629 646 643 609 639.3333333 0.675432842 0.058739553 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030008///TRAPP complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0008134///transcription factor binding+++GO:0044325///ion channel binding "GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport" 66052 66052 'Sdhc' mRNA 4115 4339 4002 215.19 224.03 221.92 224.72 244.54 233.77 220.38 234.3433333 4935 5232 4964 4152 5043.666667 1.59E-05 0.270179608 00020///Citrate cycle (TCA cycle)+++00190///Oxidative phosphorylation+++01200///Carbon metabolism+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045281///succinate dehydrogenase complex" "GO:0000104///succinate dehydrogenase activity+++GO:0009055///electron transfer activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0020037///heme binding+++GO:0046872///metal ion binding" "GO:0006099///tricarboxylic acid cycle+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0022900///electron transport chain" 66053 66053 'Ppil2' mRNA 1898.81 1920.95 2017.42 53.72 54.24 60.56 53.2 55.73 55.8 56.17333333 54.91 2214.5 2267.27 2241.13 1945.726667 2240.966667 0.022279727 0.190638755 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0016567///protein ubiquitination+++GO:0072659///protein localization to plasma membrane 66054 66054 'Cndp2' mRNA 4345 4808 4690 113.46 122.8 129.2 103.73 103.2 98.16 121.82 101.6966667 4584 4438 4199 4614.333333 4407 0.326534961 -0.079656214 00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00410///beta-Alanine metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004180///carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity+++GO:0103046///alanylglutamate dipeptidase activity GO:0006508///proteolysis 66055 66055 'Sf3b6' mRNA 787 816 802 43.96 45.04 47.53 57.07 56.53 54.25 45.51 55.95 1172 1132 1077 801.6666667 1127 1.54E-07 0.478813248 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0001825///blastocyst formation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 66056 66056 'Zfp524' mRNA 347 281 302 19.19 15.16 17.77 17.16 16.6 16.68 17.37333333 16.81333333 351 333 330 310 338 0.542734895 0.112219457 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 66058 66058 'Tmem176a' mRNA 14634 14332 13816 891.97 864.77 894.67 1484.68 1500.16 1450.19 883.8033333 1478.343333 27907 27447 26331 14260.66667 27228.33333 1.09E-81 0.921329255 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:2001199///negative regulation of dendritic cell differentiation 66059 66059 'Krtcap2' mRNA 1486.56 1351.72 1431.38 220.51 200.12 225.85 260.35 319.38 275.43 215.4933333 285.0533333 1981.66 2392 2037 1423.22 2136.886667 2.57E-09 0.575438457 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008047///enzyme activator activity GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0042543///protein N-linked glycosylation via arginine+++GO:0050790///regulation of catalytic activity 66060 66060 'Cystm1' mRNA 4931 5129 5158 481.22 495.48 534.04 402.72 446.4 423.52 503.58 424.2133333 4826 5203 4878 5072.666667 4969 0.642768545 -0.042214146 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 66061 66061 'Tctex1d2' mRNA 575 563 504 46.66 45.15 43.16 40.74 36.14 38.47 44.99 38.45 580 499 527 547.3333333 535.3333333 0.784026243 -0.043041528 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005868///cytoplasmic dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031021///interphase microtubule organizing center+++GO:0097546///ciliary base GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement+++GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:1902017///regulation of cilium assembly+++GO:1905799///regulation of intraciliary retrograde transport 66065 66065 'Hsd17b14' mRNA 824 834 867 44.77 45.37 50.31 7.4 6.91 7.79 46.81666667 7.366666667 155 144 158 841.6666667 152.3333333 4.30E-83 -2.479957209 GO:0005829///cytosol GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0047045///testosterone 17-beta-dehydrogenase (NADP+) activity GO:0006706///steroid catabolic process 66066 66066 'Gng11' mRNA 637 578 644 51.18 46.01 54.91 96.77 105.91 100.65 50.7 101.11 1379 1470 1385 619.6666667 1411.333333 2.59E-33 1.174307223 04014///Ras signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++04713///Circadian entrainment+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04725///Cholinergic synapse+++04726///Serotonergic synapse+++04727///GABAergic synapse+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031680///G-protein beta/gamma-subunit complex GO:0031681///G-protein beta-subunit binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 66067 66067 'Gtpbp8' mRNA 166.23 154.06 152.54 7.87 7.2 7.59 11.2 11.32 11.09 7.553333333 11.20333333 273.29 271.25 262.04 157.61 268.86 8.72E-06 0.760570547 GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0008150///biological_process 66069 66069 'Snupn' mRNA 607.81 699.58 619.17 20.14 23.07 22.15 19.65 18.27 19.65 21.78666667 19.19 622.26 579.43 606.34 642.1866667 602.6766667 0.431525285 -0.102560612 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0003723///RNA binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0061015///snRNA import into nucleus 66070 66070 'Cwc15' mRNA 1197 1219 1245 64.33 64.71 70.98 72.09 70.12 72.77 66.67333333 71.66 1539 1460 1502 1220.333333 1500.333333 7.89E-04 0.284593964 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005739///mitochondrion+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome" 66071 66071 'Ethe1' mRNA 721 730 685 48.23 48.61 48.75 53.02 60.93 52.93 48.53 55.62666667 907 1010 871 712 929.3333333 3.44E-04 0.374058333 00920///Sulfur metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050313///sulfur dioxygenase activity+++GO:0051213///dioxygenase activity" GO:0006749///glutathione metabolic process+++GO:0070813///hydrogen sulfide metabolic process 66072 66072 'Sdhaf2' mRNA 872 982 923 15.43 17.1 17.33 20.87 20.68 21.06 16.62 20.87 1357 1313 1326 925.6666667 1332 4.37E-09 0.512889935 GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0003674///molecular_function "GO:0006099///tricarboxylic acid cycle+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0006470///protein dephosphorylation+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0018293///protein-FAD linkage+++GO:0034553///mitochondrial respiratory chain complex II assembly+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 66073 66073 'Txndc12' mRNA 860 956 935 40.95 44.94 47.24 58.49 64.86 58.42 44.37666667 60.59 1410 1525 1362 917 1432.333333 2.07E-11 0.631255527 00480///Glutathione metabolism GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0019153///protein-disulfide reductase (glutathione) activity GO:0060548///negative regulation of cell death+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 66074 66074 'Tmem167' mRNA 1059 1122 1158 5.12 5.33 5.94 8.93 8.67 8.71 5.463333333 8.77 2126 2017 2009 1113 2050.666667 1.69E-26 0.867613077 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0009306///protein secretion+++GO:0045054///constitutive secretory pathway+++GO:0046907///intracellular transport 66075 66075 'Chchd3' mRNA 2547.47 2475.54 2328.24 71.98 69.91 72.18 62.01 60.7 62.14 71.35666667 61.61666667 2234.53 2138.76 2155.73 2450.416667 2176.34 0.007413317 -0.182500587 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0061617///MICOS complex GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0060090///molecular adaptor activity GO:0007007///inner mitochondrial membrane organization+++GO:0008053///mitochondrial fusion+++GO:0042407///cristae formation 66077 66077 'Aurkaip1' mRNA 1149 1226 1154 57.95 61.16 61.76 65.65 69.45 66.83 60.29 67.31 1495 1540 1469 1176.333333 1501.333333 3.59E-05 0.340647135 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034751///aryl hydrocarbon receptor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function+++GO:0003712///transcription coregulator activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0036004///GAF domain binding+++GO:0051082///unfolded protein binding "GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006626///protein targeting to mitochondrion+++GO:0006805///xenobiotic metabolic process+++GO:0010738///regulation of protein kinase A signaling+++GO:0016567///protein ubiquitination+++GO:0022417///protein maturation by protein folding+++GO:0045862///positive regulation of proteolysis+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity" 66078 66078 'Tsen34' mRNA 3390 3404 2804 140.67 139.41 124.5 112.69 130.47 120.24 134.86 121.1333333 3052 3484 3168 3199.333333 3234.666667 0.932088724 0.009190793 GO:0000214///tRNA-intron endonuclease complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000213///tRNA-intron endonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0005515///protein binding+++GO:0016829///lyase activity "GO:0000379///tRNA-type intron splice site recognition and cleavage+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 66079 66079 'Tmem42' mRNA 549 524 485 32.63 30.74 30.39 19.9 19.44 20.46 31.25333333 19.93333333 379 362 368 519.3333333 369.6666667 4.00E-05 -0.501111242 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66082 66082 'Abhd6' mRNA 1179.59 1234.3 1176.36 24.85 26.57 27.44 19.68 21.83 20.49 26.28666667 20.66666667 1054.55 1084.75 1038.72 1196.75 1059.34 0.039514297 -0.187849411 04723///Retrograde endocannabinoid signaling GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0031966///mitochondrial membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0003824///catalytic activity+++GO:0004620///phospholipase activity+++GO:0016787///hydrolase activity+++GO:0047372///acylglycerol lipase activity GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0030336///negative regulation of cell migration+++GO:0046464///acylglycerol catabolic process+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0052651///monoacylglycerol catabolic process+++GO:0060292///long-term synaptic depression+++GO:0099178///regulation of retrograde trans-synaptic signaling by endocanabinoid+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:2000124///regulation of endocannabinoid signaling pathway+++GO:2001311///lysobisphosphatidic acid metabolic process 66083 66083 'Setd6' mRNA 500 534 111 18.18 20.13 4.75 5.78 11.85 11.59 14.35333333 9.74 156 348 336 381.6666667 280 0.66278745 -0.422411108 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0051059///NF-kappaB binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0018022///peptidyl-lysine methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0019827///stem cell population maintenance+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0048863///stem cell differentiation+++GO:0050727///regulation of inflammatory response 66084 66084 'Rmnd1' mRNA 519 474 431 15.83 14.45 13.6 12.6 14.62 15.74 14.62666667 14.32 474 550 547 474.6666667 523.6666667 0.373552916 0.133521427 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0006412///translation+++GO:0070131///positive regulation of mitochondrial translation 66085 66085 'Eif3f' mRNA 5445 5419 4761 213.35 209.43 197.92 137.06 135.25 142.02 206.9 138.11 4018 3869 4028 5208.333333 3971.666667 1.20E-12 -0.40071151 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003743///translation initiation factor activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0031369///translation initiation factor binding+++GO:0042802///identical protein binding+++GO:0070122///isopeptidase activity+++GO:0101005///ubiquitinyl hydrolase activity GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0075522///IRES-dependent viral translational initiation 66086 66086 'Cep20' mRNA 1043 1127 1065 43.65 46.52 47.25 41.76 42.32 38.85 45.80666667 40.97666667 1144 1131 1028 1078.333333 1101 0.877704359 0.017996621 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0042802///identical protein binding GO:0030030///cell projection organization+++GO:0034453///microtubule anchoring+++GO:0060271///cilium assembly 66087 66087 'Emc3' mRNA 2688 2725 2654 78.35 78.25 82.06 83.39 85.19 81.7 79.55333333 83.42666667 3289 3280 3119 2689 3229.333333 1.42E-04 0.252102802 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 66089 66089 'Rmnd5b' mRNA 928 930 886 27.23 26.89 27.58 24.63 25.86 27.77 27.23333333 26.08666667 965 989 1053 914.6666667 1002.333333 0.249132976 0.121128961 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034657///GID complex GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 66090 66090 'Ypel3' mRNA 2403 2451 453 159.4 161.17 31.38 19.9 25.54 31.42 117.3166667 25.62 356 445 525 1769 442 0.007258949 -1.979864072 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:2000774///positive regulation of cellular senescence 66091 66091 'Ndufa3' mRNA 1054 1003 1416 347.11 335.26 496.64 299.26 343.09 340.53 393.0033333 327.6266667 1020 1130 1112 1157.666667 1087.333333 0.517145416 -0.110576526 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 66092 66092 'Ghitm' mRNA 10184 10616 10581 192.07 197.29 211.89 150.81 165.03 155 200.4166667 156.9466667 9197 9836 9167 10460.33333 9400 0.013791218 -0.16655678 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0006915///apoptotic process+++GO:0007007///inner mitochondrial membrane organization+++GO:0090201///negative regulation of release of cytochrome c from mitochondria 66094 66094 'Lsm7' mRNA 583 609 638 110.28 114.68 127.94 93.98 105.21 91.42 117.6333333 96.87 566 613 533 610 570.6666667 0.450476664 -0.109455515 03018///RNA degradation+++03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0097526///spliceosomal tri-snRNP complex+++GO:0120115///Lsm2-8 complex+++GO:1990726///Lsm1-7-Pat1 complex+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0008380///RNA splicing" 66096 66096 'Lamtor4' mRNA 1043 1052 981 78.75 78.65 78.6 89.84 105.01 96.98 78.66666667 97.27666667 1363 1552 1421 1025.333333 1445.333333 6.37E-08 0.48556381 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071986///Ragulator complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0060090///molecular adaptor activity GO:0008361///regulation of cell size+++GO:0032008///positive regulation of TOR signaling+++GO:0050790///regulation of catalytic activity+++GO:0061462///protein localization to lysosome+++GO:0071230///cellular response to amino acid stimulus 66098 66098 'Chchd6' mRNA 1793 1878 1927 99.95 103.43 114.18 36.74 37.06 36.21 105.8533333 36.67 758 744 720 1866 740.6666667 1.11E-54 -1.346862064 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0061617///MICOS complex GO:0006974///cellular response to DNA damage stimulus+++GO:0042407///cristae formation 66101 66101 'Ppih' mRNA 221.13 240.1 219.23 15.73 17.3 18.1 19.91 21.85 17.24 17.04333333 19.66666667 310.31 319.4 258.64 226.82 296.1166667 0.030155024 0.37233422 03040///Spliceosome GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071001///U4/U6 snRNP GO:0003674///molecular_function+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0043021///ribonucleoprotein complex binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006457///protein folding+++GO:0008150///biological_process+++GO:0008380///RNA splicing+++GO:0045070///positive regulation of viral genome replication 66102 66102 'Cxcl16' mRNA 618.76 583.22 646.6 24.51 22.78 27.17 89.21 83.23 90.49 24.82 87.64333333 2587.34 2355.24 2538.72 616.1933333 2493.766667 5.13E-122 2.003391031 04060///Cytokine-cytokine receptor interaction+++04062///Chemokine signaling pathway GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0042379///chemokine receptor binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding "GO:0006898///receptor-mediated endocytosis+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0010818///T cell chemotaxis+++GO:0030154///cell differentiation+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0034097///response to cytokine+++GO:0034341///response to interferon-gamma+++GO:0034612///response to tumor necrosis factor+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048247///lymphocyte chemotaxis+++GO:0071222///cellular response to lipopolysaccharide" 66104 66104 'Tceal6' mRNA 0 1.08 0.8 0 0.06 0.05 0 0 0 0.036666667 0 0 0 0 0.626666667 0 0.863090843 -0.97353728 GO:0005634///nucleus GO:0003746///translation elongation factor activity+++GO:0050699///WW domain binding GO:0006414///translational elongation 66105 66105 'Ube2d3' mRNA 5904.27 6223.92 4009.11 115.29 118.55 81.98 87.93 119.73 111.93 105.2733333 106.53 5045.64 6644.9 6147.55 5379.1 5946.03 0.561235071 0.145307729 04013///MAPK signaling pathway - fly+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 66106 66106 'Smpx' mRNA 3577 3706 3476 214.28 219.46 220.94 20.84 21.97 22.81 218.2266667 21.87333333 399 410 422 3586.333333 410.3333333 0 -3.138855833 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005927///muscle tendon junction+++GO:0031430///M band+++GO:0043034///costamere+++GO:0043292///contractile fiber "GO:0004108///citrate (Si)-synthase activity+++GO:0016740///transferase activity+++GO:0046912///transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer" GO:0005975///carbohydrate metabolic process+++GO:0006084///acetyl-CoA metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006107///oxaloacetate metabolic process 66107 66107 'Wfdc21' mRNA 6 9 12 1.28 1.93 2.71 3.2 2.52 3.91 1.973333333 3.21 17 13 20 9 16.66666667 0.272472813 0.867363077 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008047///enzyme activator activity+++GO:0030414///peptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0032496///response to lipopolysaccharide+++GO:0034612///response to tumor necrosis factor+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0050790///regulation of catalytic activity+++GO:0050872///white fat cell differentiation+++GO:0052547///regulation of peptidase activity 66108 66108 'Ndufa9' mRNA 1667 1720 1707 76.06 77.46 82.64 97.41 99.12 96.81 78.72 97.78 2451 2433 2356 1698 2413.333333 5.68E-12 0.494602651 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005759///mitochondrial matrix+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain GO:0003954///NADH dehydrogenase activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0007623///circadian rhythm+++GO:0009749///response to glucose+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:1901006///ubiquinone-6 biosynthetic process 66109 66109 'Tspan13' mRNA 10063 10573 10210 299.25 309.8 322.1 140.88 139.55 142.38 310.3833333 140.9366667 5446 5266 5327 10282 5346.333333 2.28E-70 -0.955999063 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005246///calcium channel regulator activity+++GO:0005515///protein binding GO:1903169///regulation of calcium ion transmembrane transport 66111 66111 'Tmed3' mRNA 2012 1951 1883 91.64 87.71 90.99 130.48 135.95 132.98 90.11333333 133.1366667 3289 3343 3242 1948.666667 3291.333333 5.45E-31 0.744998651 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030126///COPI vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport 66112 66112 'Mtarc1' mRNA 1 0 2 0.03 0 0.06 0.05 0.21 0 0.03 0.086666667 2 9 0 1 3.666666667 0.409447783 1.848397568 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1903958///nitric-oxide synthase complex "GO:0003824///catalytic activity+++GO:0008940///nitrate reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016661///oxidoreductase activity, acting on other nitrogenous compounds as donors+++GO:0030151///molybdenum ion binding+++GO:0030170///pyridoxal phosphate binding+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050421///nitrite reductase (NO-forming) activity+++GO:0098809///nitrite reductase activity" GO:0006809///nitric oxide biosynthetic process+++GO:0042126///nitrate metabolic process+++GO:0070458///cellular detoxification of nitrogen compound 66113 66113 'Apoa5' mRNA 0 3 1 0 0.07 0.03 0 0 0 0.033333333 0 0 0 0 1.333333333 0 0.484689396 -2.854031813 03320///PPAR signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0042627///chylomicron GO:0005543///phospholipid binding+++GO:0008047///enzyme activator activity+++GO:0008201///heparin binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0019899///enzyme binding+++GO:0031210///phosphatidylcholine binding+++GO:0035473///lipase binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0060228///phosphatidylcholine-sterol O-acyltransferase activator activity+++GO:0060229///lipase activator activity+++GO:0060230///lipoprotein lipase activator activity+++GO:0070325///lipoprotein particle receptor binding GO:0006641///triglyceride metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006869///lipid transport+++GO:0010873///positive regulation of cholesterol esterification+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0010902///positive regulation of very-low-density lipoprotein particle remodeling+++GO:0019433///triglyceride catabolic process+++GO:0030300///regulation of intestinal cholesterol absorption+++GO:0033344///cholesterol efflux+++GO:0033700///phospholipid efflux+++GO:0034370///triglyceride-rich lipoprotein particle remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0034380///high-density lipoprotein particle assembly+++GO:0042157///lipoprotein metabolic process+++GO:0042246///tissue regeneration+++GO:0042632///cholesterol homeostasis+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0050996///positive regulation of lipid catabolic process+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0055090///acylglycerol homeostasis+++GO:0070328///triglyceride homeostasis 66114 66114 'Dnajc30' mRNA 796.79 790.93 752.08 42.47 41.65 42.54 38.55 42.74 39.89 42.22 40.39333333 829.72 897.08 830.14 779.9333333 852.3133333 0.298453896 0.118020757 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006754///ATP biosynthetic process+++GO:0007420///brain development+++GO:1905706///regulation of mitochondrial ATP synthesis coupled proton transport 66116 66116 'Nat8f1' mRNA 1323.65 1369.98 1214.17 68.7 68.52 67.45 114.57 113.71 111.07 68.22333333 113.1166667 2160.21 2075.35 2023.18 1302.6 2086.246667 2.99E-21 0.669577406 00480///Glutathione metabolism GO:0005615///extracellular space+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0010628///positive regulation of gene expression+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 66117 66117 'Fmc1' mRNA 341 309 373 71.73 65.3 83.35 62.18 75.7 73.83 73.46 70.57 335 395 382 341 370.6666667 0.590787978 0.106094451 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0050995///negative regulation of lipid catabolic process+++GO:0061469///regulation of type B pancreatic cell proliferation 66118 66118 'Sarnp' mRNA 1253 1250 1232 73.29 72.33 76.23 84.67 90.79 84.72 73.95 86.72666667 1651 1728 1598 1245 1659 7.91E-07 0.402471208 GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006406///mRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 66119 66119 'Tomm6' mRNA 2154 2099 1881 145.79 140.42 135.07 124.84 151.24 129.5 140.4266667 135.1933333 2116 2498 2121 2044.666667 2245 0.19556395 0.126615315 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane GO:0003674///molecular_function GO:0015031///protein transport 66120 66120 'Fkbp11' mRNA 166 165 187 15.86 15.66 18.99 35.31 42.96 35.43 16.83666667 37.9 423 498 410 172.6666667 443.6666667 3.82E-17 1.348290497 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0061077///chaperone-mediated protein folding 66121 66121 'Chchd1' mRNA 878 836 818 113.29 107.44 112.04 120.14 134.68 117.99 110.9233333 124.27 1062 1157 1005 844 1074.666667 7.06E-04 0.3376932 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005829///cytosol+++GO:0005840///ribosome GO:0008150///biological_process+++GO:0032543///mitochondrial translation 66124 66124 'Josd2' mRNA 1224 1160 1185 87.71 81.02 89.17 87.74 91.71 86.11 85.96666667 88.52 1445 1443 1337 1189.666667 1408.333333 0.009413334 0.230882457 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination 66125 66125 'Sf3b5' mRNA 943 945 840 90.17 89.67 85.24 106.02 108.76 106.4 88.36 107.06 1268 1266 1228 909.3333333 1254 7.19E-08 0.453759369 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome GO:0003723///RNA binding+++GO:1990935///splicing factor binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 66126 66126 'Elof1' mRNA 2689 2595 2616 174.42 164.87 177.67 117.09 125.2 116.8 172.32 119.6966667 2020 2106 1929 2633.333333 2018.333333 8.16E-08 -0.395865249 GO:0005634///nucleus+++GO:0008023///transcription elongation factor complex GO:0000993///RNA polymerase II complex binding+++GO:0046872///metal ion binding GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0048096///chromatin-mediated maintenance of transcription 66128 66128 'Mrps36' mRNA 608 621 635 60.21 61.05 66.75 59.59 64.81 64.56 62.67 62.98666667 688 728 719 621.3333333 711.6666667 0.122635302 0.183399233 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0009353///mitochondrial oxoglutarate dehydrogenase complex GO:0006103///2-oxoglutarate metabolic process 66129 66129 'Prxl2c' mRNA 1499.52 1620.19 1592.72 27.36 29.09 30.82 25.12 22.85 22.94 29.09 23.63666667 1584.24 1407.49 1401.14 1570.81 1464.29 0.230333854 -0.115030447 GO:0005575///cellular_component GO:0016209///antioxidant activity GO:0045821///positive regulation of glycolytic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0098869///cellular oxidant detoxification 66131 66131 'Tipin' mRNA 548 556 513 22.42 21.2 21.87 27.21 28.69 29.73 21.83 28.54333333 741 748 764 539 751 6.63E-06 0.467987309 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031298///replication fork protection complex GO:0003677///DNA binding+++GO:0005515///protein binding GO:0000076///DNA replication checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0009411///response to UV+++GO:0031573///intra-S DNA damage checkpoint+++GO:0043111///replication fork arrest+++GO:0044770///cell cycle phase transition+++GO:0048478///replication fork protection+++GO:0051301///cell division 66132 66132 'Prorp' mRNA 192.7 179.09 207.06 3.39 3.1 3.86 3.67 4.41 3.21 3.45 3.763333333 240.19 281.66 203.63 192.95 241.8266667 0.139727297 0.311008374 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0030678///mitochondrial ribonuclease P complex+++GO:0042645///mitochondrial nucleoid GO:0004518///nuclease activity+++GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0097745///mitochondrial tRNA 5'-end processing" 66136 66136 'Znrd1' mRNA 412 423 406 42.25 43.04 44.04 56.74 54.67 52.24 43.11 54.55 634 595 565 413.6666667 598 8.79E-06 0.519441096 03020///RNA polymerase GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex GO:0003676///nucleic acid binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006379///mRNA cleavage" 66138 66138 'Bud23' mRNA 923.21 925.07 918.92 31.14 31.18 32.52 35.17 36.27 34.83 31.61333333 35.42333333 1227.28 1229.92 1154.86 922.4 1204.02 3.03E-05 0.371952579 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0008168///methyltransferase activity+++GO:0016435///rRNA (guanine) methyltransferase activity+++GO:0016740///transferase activity+++GO:0046982///protein heterodimerization activity GO:0006325///chromatin organization+++GO:0006364///rRNA processing+++GO:0032259///methylation+++GO:0042254///ribosome biogenesis+++GO:0070476///rRNA (guanine-N7)-methylation+++GO:2000234///positive regulation of rRNA processing 66139 66139 'Mymk' mRNA 1 0 0 0.05 0 0 0 0.2 0.09 0.016666667 0.096666667 0 5 2 0.333333333 2.333333333 0.346340198 2.710084592 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0005515///protein binding GO:0007517///muscle organ development+++GO:0007520///myoblast fusion+++GO:0014905///myoblast fusion involved in skeletal muscle regeneration+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045026///plasma membrane fusion+++GO:1904206///positive regulation of skeletal muscle hypertrophy 66140 66140 'Ska2' mRNA 412 460 397 18.36 20.23 18.77 19.44 18.54 19.1 19.12 19.02666667 501 466 476 423 481 0.198601099 0.174763113 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule" GO:0008017///microtubule binding GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0051301///cell division 66141 66141 'Ifitm3' mRNA 10506 10465 10435 1196.27 1184.82 1261.15 3677.2 4108.04 3753.94 1214.08 3846.393333 36880 40068 36304 10468.66667 37750.66667 2.39E-206 1.838641362 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0048471///perinuclear region of cytoplasm GO:0002376///immune system process+++GO:0006898///receptor-mediated endocytosis+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0030336///negative regulation of cell migration+++GO:0032897///negative regulation of viral transcription+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 66142 66142 'Cox7b' mRNA 2188 2169 2330 139.71 136.97 157.87 160.35 190.4 172.67 144.85 174.4733333 2879 3332 2996 2229 3069 3.24E-07 0.448465277 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045277///respiratory chain complex IV GO:0003674///molecular_function+++GO:0004129///cytochrome-c oxidase activity GO:0006119///oxidative phosphorylation+++GO:0007417///central nervous system development+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport 66143 66143 'Eef1e1' mRNA 259 271 282 15.79 16.34 18.24 25.57 26.89 25.36 16.79 25.94 481 493 461 270.6666667 478.3333333 2.45E-09 0.808381974 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0003746///translation elongation factor activity+++GO:0005515///protein binding "GO:0006412///translation+++GO:0006414///translational elongation+++GO:0008285///negative regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000774///positive regulation of cellular senescence+++GO:2001235///positive regulation of apoptotic signaling pathway" 66144 66144 'Atp6v1f' mRNA 3368 3298 3348 394.89 384.62 416.65 506.08 564.3 522.26 398.72 530.88 4928 5343 4903 3338 5058 1.35E-17 0.587578769 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0016020///membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0033180///proton-transporting V-type ATPase, V1 domain" "GO:0042625///ATPase coupled ion transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:1902600///proton transmembrane transport 66146 66146 'Maco1' mRNA 472.58 459.72 406.8 6.4 6.2 5.83 4.35 4.16 4.69 6.143333333 4.4 368.57 347.8 376.25 446.3666667 364.2066667 0.023556745 -0.303221637 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0031965///nuclear membrane+++GO:0043005///neuron projection+++GO:0044306///neuron projection terminus+++GO:0045202///synapse GO:0008017///microtubule binding+++GO:0051015///actin filament binding GO:0006935///chemotaxis+++GO:0007420///brain development+++GO:0023041///neuronal signal transduction 66147 66147 'Necap2' mRNA 1741 1815 1679 52.29 53.71 53.49 86.11 86.53 87.47 53.16333333 86.70333333 3296 3233 3240 1745 3256.333333 7.21E-46 0.888918646 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030125///clathrin vesicle coat+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 66148 66148 'Dnajc15' mRNA 728 758 769 82.89 85.82 92.94 105.99 107.86 98.54 87.21666667 104.13 1063 1052 953 751.6666667 1022.666667 1.64E-05 0.430935458 "GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane" GO:0001671///ATPase activator activity+++GO:0005515///protein binding "GO:0009267///cellular response to starvation+++GO:0015031///protein transport+++GO:0019216///regulation of lipid metabolic process+++GO:0030150///protein import into mitochondrial matrix+++GO:0031333///negative regulation of protein complex assembly+++GO:0050790///regulation of catalytic activity+++GO:1902957///negative regulation of mitochondrial electron transport, NADH to ubiquinone" 66151 66151 'Prr13' mRNA 1884 1960 1890 101.05 104.71 107.48 152.33 161.86 145.22 104.4133333 153.1366667 3223 3352 2988 1911.333333 3187.666667 6.84E-24 0.726202346 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 66152 66152 'Uqcr10' mRNA 2151 2190 2517 450.44 461.71 561.29 443.53 541.04 495.17 491.1466667 493.2466667 2395 2829 2568 2286 2597.333333 0.128194965 0.169402862 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0009060///aerobic respiration" 66153 66153 'Fbxo36' mRNA 449.7 470.12 463.08 30.94 32.14 33.77 11.5 12.01 12.82 32.28333333 12.11 196.37 199.86 203.88 460.9666667 200.0366667 2.53E-18 -1.220841745 GO:0005575///cellular_component GO:0003674///molecular_function 66154 66154 'Tmem14c' mRNA 876 916 811 60.21 62.29 59.08 137.07 132.26 143.13 60.52666667 137.4866667 2290 2156 2313 867.6666667 2253 4.75E-76 1.366147716 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0042802///identical protein binding GO:0006783///heme biosynthetic process+++GO:0006839///mitochondrial transport+++GO:0030218///erythrocyte differentiation+++GO:0070453///regulation of heme biosynthetic process 66155 66155 'Ufc1' mRNA 1084 1089 1071 70.64 70.2 74.06 83.11 90.75 84.97 71.63333333 86.27666667 1461 1557 1445 1081.333333 1487.666667 1.29E-07 0.448733324 GO:0005515///protein binding+++GO:0061657///UFM1 conjugating enzyme activity+++GO:0071568///UFM1 transferase activity GO:0007420///brain development+++GO:0034976///response to endoplasmic reticulum stress+++GO:0061709///reticulophagy+++GO:0071569///protein ufmylation+++GO:1990592///protein K69-linked ufmylation 66156 66156 'Anapc11' mRNA 2364 2530 2046 39.48 41.55 36.22 31.82 35.33 31.2 39.08333333 32.78333333 2217 2410 2107 2313.333333 2244.666667 0.628877571 -0.050895063 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0031461///cullin-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0097602///cullin family protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 66158 66158 'Rtl8a' mRNA 960.06 849.39 564.92 45.67 39.89 28.51 34.09 33.92 31.93 38.02333333 33.31333333 822.51 798.29 745.19 791.4566667 788.6633333 0.971770426 -0.007675812 GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 66161 66161 'Pop4' mRNA 427 343 323 20.81 16.48 16.69 21.67 21.69 21.68 17.99333333 21.68 502 495 485 364.3333333 494 0.001932048 0.429785392 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030677///ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex GO:0003723///RNA binding+++GO:0004526///ribonuclease P activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 66162 66162 'Bola2' mRNA 248 254 326 89.27 93.01 125.1 96.44 125.77 122.84 102.46 115.0166667 300 378 366 276 348 0.102592507 0.318138685 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006879///cellular iron ion homeostasis+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer 66163 66163 'Mrpl4' mRNA 2081.63 2121 2008.81 88.32 89.39 91.72 101.04 108.43 105.37 89.81 104.9466667 2614.85 2697.14 2598.43 2070.48 2636.806667 6.66E-07 0.337850223 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 66164 66164 'Nip7' mRNA 548.39 501.27 602.87 9.95 8.93 11.6 13.67 13.82 12.85 10.16 13.44666667 867.81 857.5 790.96 550.8433333 838.7566667 7.24E-07 0.590684743 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0030687///preribosome, large subunit precursor" GO:0003723///RNA binding GO:0042254///ribosome biogenesis+++GO:0042255///ribosome assembly+++GO:0042273///ribosomal large subunit biogenesis 66165 66165 'Bccip' mRNA 1297.52 1347.94 1406.12 63.62 65.25 73.14 73.6 78.8 78.13 67.33666667 76.84333333 1722.94 1799.36 1768.68 1350.526667 1763.66 1.90E-05 0.371755813 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0019908///nuclear cyclin-dependent protein kinase holoenzyme complex+++GO:0097431///mitotic spindle pole GO:0015631///tubulin binding+++GO:0019207///kinase regulator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000132///establishment of mitotic spindle orientation+++GO:0000226///microtubule cytoskeleton organization+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0034453///microtubule anchoring+++GO:0061101///neuroendocrine cell differentiation+++GO:0090307///mitotic spindle assembly 66166 66166 'S100a14' mRNA 24 29 17 1.37 1.73 1.05 2.53 1.92 1.57 1.383333333 2.006666667 50 37 30 23.33333333 39 0.142074277 0.733882427 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005509///calcium ion binding+++GO:0042379///chemokine receptor binding+++GO:0048306///calcium-dependent protein binding GO:0006915///apoptotic process+++GO:0032496///response to lipopolysaccharide+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0071624///positive regulation of granulocyte chemotaxis+++GO:0090026///positive regulation of monocyte chemotaxis 66167 66167 'Tma7' mRNA 1154.98 1116.29 1198.62 134.8 129.58 148.49 152.86 181.3 164.08 137.6233333 166.08 1495.39 1724.53 1547.52 1156.63 1589.146667 4.53E-06 0.44611231 GO:0005575///cellular_component GO:0003674///molecular_function GO:0002181///cytoplasmic translation 66168 66168 'Grina' mRNA 7610 7605 7069 245.61 241.95 243.05 313.99 324.24 315.21 243.5366667 317.8133333 10937 11026 10653 7428 10872 3.42E-27 0.53887307 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0044325///ion channel binding GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 66169 66169 'Tomm7' mRNA 856 879 1110 48.18 48.89 66.29 38.18 46.9 43.96 54.45333333 43.01333333 778 932 866 948.3333333 858.6666667 0.302319966 -0.160399171 04137///Mitophagy - animal GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0031647///regulation of protein stability+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:1903955///positive regulation of protein targeting to mitochondrion 66170 66170 'Chchd5' mRNA 322 336 334 14.95 15.39 16.45 12.78 12.56 12.29 15.59666667 12.54333333 316 303 294 330.6666667 304.3333333 0.438305085 -0.132603822 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0003674///molecular_function 66171 66171 'Pgls' mRNA 1005 1063 946 73.72 77.91 74.06 105.01 96.39 110.27 75.23 103.89 1628 1455 1648 1004.666667 1577 6.97E-15 0.639442341 00030///Pentose phosphate pathway+++01200///Carbon metabolism GO:0005737///cytoplasm GO:0016787///hydrolase activity+++GO:0017057///6-phosphogluconolactonase activity+++GO:0048029///monosaccharide binding "GO:0005975///carbohydrate metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0009051///pentose-phosphate shunt, oxidative branch" 66172 66172 'Med11' mRNA 337 302 293 24.34 21.59 22.45 37.75 36.09 34.32 22.79333333 36.05333333 599 558 526 310.6666667 561 2.05E-11 0.841092862 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0016567///protein ubiquitination 66174 66174 'Nudt14' mRNA 956 974 901 46.46 46.7 46.44 37.19 32.14 34.25 46.53333333 34.52666667 879 740 782 943.6666667 800.3333333 0.012451815 -0.24994312 GO:0005737///cytoplasm "GO:0008768///UDP-sugar diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047631///ADP-ribose diphosphatase activity" GO:0006753///nucleoside phosphate metabolic process+++GO:0019693///ribose phosphate metabolic process 66175 66175 'Mustn1' mRNA 51 61 48 2.67 3.15 2.66 16.76 16.72 16.58 2.826666667 16.68666667 368 358 352 53.33333333 359.3333333 4.13E-46 2.742568829 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0002062///chondrocyte differentiation+++GO:0010628///positive regulation of gene expression+++GO:0030326///embryonic limb morphogenesis+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0035988///chondrocyte proliferation+++GO:0042060///wound healing+++GO:0042246///tissue regeneration+++GO:1902730///positive regulation of proteoglycan biosynthetic process+++GO:1902732///positive regulation of chondrocyte proliferation 66176 66176 'Nat9' mRNA 529 526 513 27.53 27.42 28.72 21.17 20.8 22.42 27.89 21.46333333 475 429 480 522.6666667 461.3333333 0.138450215 -0.192456966 GO:0032991///protein-containing complex "GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006473///protein acetylation 66177 66177 'Ubl5' mRNA 1996.36 1959.96 2148.74 268.49 258.49 318.08 240.83 269.08 269.31 281.6866667 259.74 1988.53 2109.8 2113.02 2035.02 2070.45 0.924287695 0.011073068 04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0031386///protein tag "GO:0000398///mRNA splicing, via spliceosome+++GO:0006464///cellular protein modification process" 66179 66179 'Ogfod3' mRNA 1254.98 1236.86 1224.96 61.59 59.93 63.78 42.03 39.63 42.09 61.76666667 41.25 982.91 903.98 951.98 1238.933333 946.29 3.17E-06 -0.401814338 GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" 66180 66180 'P3h4' mRNA 2364 2381 2056 65.45 64.98 60.45 38.25 39.67 36.94 63.62666667 38.28666667 1589 1607 1484 2267 1560 4.87E-14 -0.548407959 GO:0000795///synaptonemal complex+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:1902494///catalytic complex GO:0005515///protein binding+++GO:0005518///collagen binding GO:0017185///peptidyl-lysine hydroxylation+++GO:0030199///collagen fibril organization+++GO:0032964///collagen biosynthetic process+++GO:0046849///bone remodeling 66181 66181 'Nop10' mRNA 1640 1590 1719 155.66 149.75 173.16 138.76 165.67 141.97 159.5233333 148.8 1672 1943 1651 1649.666667 1755.333333 0.523568041 0.076651788 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0031429///box H/ACA snoRNP complex+++GO:0090661///box H/ACA telomerase RNP complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030515///snoRNA binding+++GO:0034513///box H/ACA snoRNA binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0006364///rRNA processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031118///rRNA pseudouridine synthesis+++GO:0031120///snRNA pseudouridine synthesis+++GO:0042254///ribosome biogenesis 66183 66183 'Sptssb' mRNA 10 8 4 0.33 0.23 0.14 0.09 0.03 0.03 0.233333333 0.05 3 1 1 7.333333333 1.666666667 0.115151934 -2.142589941 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex GO:0004758///serine C-palmitoyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0007029///endoplasmic reticulum organization+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:1904220///regulation of serine C-palmitoyltransferase activity 66185 66185 'Virma' mRNA 1231 1237 1093 9.33 9.22 8.79 8.59 7.29 8.89 9.113333333 8.256666667 1305 1082 1308 1187 1231.666667 0.739263611 0.042278562 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0080009///mRNA methylation+++GO:0110104///mRNA alternative polyadenylation 66190 66190 'Acer3' mRNA 397 401 385 5.45 5.42 5.61 12.03 10.55 11.02 5.493333333 11.2 1007 862 893 394.3333333 920.6666667 1.50E-30 1.210455021 00600///Sphingolipid metabolism GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0046872///metal ion binding+++GO:0070774///phytoceramidase activity+++GO:0071633///dihydroceramidase activity+++GO:0102121///ceramidase activity" GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0042552///myelination+++GO:0043067///regulation of programmed cell death+++GO:0046512///sphingosine biosynthetic process+++GO:0046514///ceramide catabolic process+++GO:0071602///phytosphingosine biosynthetic process 66191 66191 'Ier3ip1' mRNA 1650 1707 1744 70.76 72.23 79.35 67.07 77.05 74.63 74.11333333 72.91666667 1796 2013 1933 1700.333333 1914 0.092679083 0.158565218 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane GO:0003674///molecular_function GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0035265///organ growth+++GO:0050714///positive regulation of protein secretion+++GO:2000269///regulation of fibroblast apoptotic process 66192 66192 'Lage3' mRNA 520 460 486 47.43 41.61 47.04 46.24 49.54 45.67 45.36 47.15 580 605 553 488.6666667 579.3333333 0.070158878 0.233323081 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0008033///tRNA processing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070525///tRNA threonylcarbamoyladenosine metabolic process 66193 66193 'Pithd1' mRNA 1188 1357 964 45.47 51.23 39.15 22.52 37.73 33.27 45.28333333 31.17333333 676 1105 966 1169.666667 915.6666667 0.207627051 -0.353418714 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0097598///sperm cytoplasmic droplet GO:0005515///protein binding "GO:0007286///spermatid development+++GO:0007341///penetration of zona pellucida+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0061956///penetration of cumulus oophorus+++GO:0097722///sperm motility" 66194 66194 'Pycrl' mRNA 639 651 653 28.45 28.65 30.76 27.63 32.13 26.53 29.28666667 28.76333333 709 807 660 647.6666667 725.3333333 0.251467344 0.151696649 00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0004126///cytidine deaminase activity+++GO:0004735///pyrroline-5-carboxylate reductase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding GO:0006561///proline biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009972///cytidine deamination+++GO:0055129///L-proline biosynthetic process 66196 66196 'Myo19' mRNA 288.98 256.74 274.52 3.91 3.51 4.06 2.45 3.01 2.81 3.826666667 2.756666667 199.9 233.32 222.4 273.4133333 218.54 0.063488985 -0.33436135 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0031982///vesicle GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0032027///myosin light chain binding+++GO:0051015///actin filament binding+++GO:0060002///plus-end directed microfilament motor activity GO:0007015///actin filament organization+++GO:0030050///vesicle transport along actin filament+++GO:0032465///regulation of cytokinesis+++GO:0034642///mitochondrion migration along actin filament+++GO:0090140///regulation of mitochondrial fission 66197 66197 'Cks2' mRNA 42 37 30 4.34 3.8 3.29 34.62 33.26 30.92 3.81 32.93333333 383 358 330 36.33333333 357 2.27E-53 3.286888507 05200///Pathways in cancer+++05222///Small cell lung cancer GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0019005///SCF ubiquitin ligase complex GO:0003682///chromatin binding+++GO:0016301///kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0042393///histone binding+++GO:0043130///ubiquitin binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007127///meiosis I+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0009790///embryo development+++GO:0016310///phosphorylation+++GO:0044772///mitotic cell cycle phase transition+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division 66198 66198 'Them5' mRNA 42 43 70 2.05 2.07 3.62 1.23 1.48 1.76 2.58 1.49 29 34 40 51.66666667 34.33333333 0.173405203 -0.612060432 00062///Fatty acid elongation GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0035965///cardiolipin acyl-chain remodeling 66199 66199 'Commd4' mRNA 604 668 604 49.48 54.26 52.53 79.18 81.35 76.18 52.09 78.90333333 1106 1107 1028 625.3333333 1080.333333 1.98E-16 0.777782873 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 66200 66200 'Commd6' mRNA 1141 1212 1187 86.53 91.07 95.63 77.02 80.85 77.79 91.07666667 78.55333333 1163 1190 1135 1180 1162.666667 0.780544402 -0.033613588 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0051059///NF-kappaB binding GO:0032088///negative regulation of NF-kappaB transcription factor activity 66201 66201 'Vta1' mRNA 968 1024 972 43.34 45.22 46.19 44.75 41.37 45.28 44.91666667 43.8 1153 1040 1131 988 1108 0.113346531 0.152972948 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008022///protein C-terminus binding GO:0015031///protein transport+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0046755///viral budding+++GO:0071985///multivesicular body sorting pathway 66202 66202 '1110059G10Rik' mRNA 359 405 300 5.82 6.46 5.16 5.85 5.83 5.72 5.813333333 5.8 415 404 393 354.6666667 404 0.247949203 0.180575659 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66203 66203 'Lce1m' mRNA 1 0 0 0.08 0 0 0.13 0 0.14 0.026666667 0.09 2 0 2 0.333333333 1.333333333 0.612136881 1.872960033 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0008544///epidermis development+++GO:0031424///keratinization 66204 66204 'Acyp1' mRNA 287.58 266.95 289 32.26 29.03 34.35 22.46 27.05 26.64 31.88 25.38333333 232.42 272.26 266.02 281.1766667 256.9 0.476767245 -0.141086835 00620///Pyruvate metabolism GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity GO:0008150///biological_process 66205 66205 'Cd302' mRNA 523 481 518 23.31 21.16 24.49 88.61 85.03 87.75 22.98666667 87.13 2284 2138 2188 507.3333333 2203.333333 4.52E-136 2.105338269 GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0005938///cell cortex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030175///filopodium+++GO:0042995///cell projection GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity GO:0006909///phagocytosis 66206 66206 '1110059E24Rik' mRNA 932.35 1031.29 989.6 38.88 42.43 43.78 28.2 29.57 28.37 41.69666667 28.71333333 776.69 794.66 755.95 984.4133333 775.7666667 3.23E-04 -0.356608071 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66208 66208 'Nenf' mRNA 2394 2224 2158 254 234.42 243.01 190.8 189.16 192.03 243.81 190.6633333 2055 1982 1995 2258.666667 2010.666667 0.014605342 -0.179230181 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0032099///negative regulation of appetite+++GO:0043410///positive regulation of MAPK cascade+++GO:1901215///negative regulation of neuron death 66209 66209 'Inip' mRNA 459 542.98 559 7.88 9.21 10.16 11.15 12.07 11.51 9.083333333 11.57666667 749 791 749.7 520.3266667 763.2333333 9.97E-06 0.539291 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break+++GO:0070876///SOSS complex GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation 66211 66211 'Rpl3l' mRNA 0 2 0 0 0.09 0 0.05 0.16 0 0.03 0.07 1 3 0 0.666666667 1.333333333 0.780862319 1.034094741 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation 66212 66212 'Sec61b' mRNA 1222.02 1215.01 1232.81 176.79 175.36 189.34 316.21 341.84 347.06 180.4966667 335.0366667 2489.97 2614.13 2631.63 1223.28 2578.576667 1.39E-44 1.063802202 03060///Protein export+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05110///Vibrio cholerae infection GO:0005783///endoplasmic reticulum+++GO:0005784///Sec61 translocon complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044322///endoplasmic reticulum quality control compartment GO:0005515///protein binding+++GO:0043022///ribosome binding+++GO:0048408///epidermal growth factor binding "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0031204///posttranslational protein targeting to membrane, translocation" 66213 66213 'Med7' mRNA 732 736 720 28.22 28.76 29.14 26.37 24.18 25.43 28.70666667 25.32666667 772 704 719 729.3333333 731.6666667 0.954227407 -0.00804926 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex+++GO:0016604///nuclear body GO:0003712///transcription coregulator activity+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance 66214 66214 'Rgcc' mRNA 2014 2082 1986 144.22 147.56 150.9 106.12 111.35 100.46 147.56 105.9766667 1698 1736 1553 2027.333333 1662.333333 1.40E-04 -0.298009094 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0070412///R-SMAD binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001100///negative regulation of exit from mitosis+++GO:0001818///negative regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0006956///complement activation+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016525///negative regulation of angiogenesis+++GO:0032147///activation of protein kinase activity+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest+++GO:0071456///cellular response to hypoxia+++GO:0071850///mitotic cell cycle arrest+++GO:0072537///fibroblast activation+++GO:0090272///negative regulation of fibroblast growth factor production+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:1901991///negative regulation of mitotic cell cycle phase transition+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000573///positive regulation of DNA biosynthetic process 66218 66218 'Ndufb9' mRNA 3891 3930 3744 407.77 409.11 416.43 393.77 419.44 408.58 411.1033333 407.2633333 4294 4450 4298 3855 4347.333333 0.010564087 0.162297959 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly" 66220 66220 'Zdhhc12' mRNA 380 358 368 20.35 18.96 20.94 24.46 25.06 22.66 20.08333333 24.06 524 524 469 368.6666667 505.6666667 6.37E-04 0.443348494 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" "GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly" 66222 66222 'Serpinb1a' mRNA 45 53 41 1.31 1.56 1.27 21.41 21.65 20.48 1.38 21.18 832 819 773 46.33333333 808 2.88E-133 4.114374944 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0062023///collagen-containing extracellular matrix GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity GO:0006954///inflammatory response+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019725///cellular homeostasis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0042176///regulation of protein catabolic process+++GO:0044342///type B pancreatic cell proliferation+++GO:0045088///regulation of innate immune response 66223 66223 'Mrpl35' mRNA 526.08 586.78 599.8 7.72 8.47 9.33 9.29 10.22 9.4 8.506666667 9.636666667 728.68 782.84 714.1 570.8866667 741.8733333 0.002148113 0.365182779 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 66225 66225 'Llph' mRNA 510.22 561.86 497.87 26.63 29.04 27.8 36.86 38.48 36.14 27.82333333 37.16 831.1 843.5 808.52 523.3166667 827.7066667 1.74E-10 0.652214014 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0001099///basal RNA polymerase II transcription machinery binding+++GO:0005515///protein binding GO:0060999///positive regulation of dendritic spine development+++GO:0097484///dendrite extension 66226 66226 'Trappc2' mRNA 1054 1128 1042 43.89 46.25 45.98 30.6 30.78 29.07 45.37333333 30.15 845 828 776 1074.666667 816.3333333 8.12E-06 -0.408116064 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030008///TRAPP complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0044325///ion channel binding "GO:0001501///skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport" 66229 66229 'Rpl7l1' mRNA 1764.16 1816.43 1862.29 37.59 38.1 42.09 51.29 53.52 47.58 39.26 50.79666667 2769.43 2821.64 2487.31 1814.293333 2692.793333 3.90E-12 0.5563072 GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0001825///blastocyst formation" 66230 66230 'Mrps28' mRNA 472 386 465 46.17 37.47 48.27 55.17 52.38 50.88 43.97 52.81 645 596 574 441 605 9.56E-04 0.440653506 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0032543///mitochondrial translation 66231 66231 'Thoc7' mRNA 869.83 946.57 909.63 54.7 60.12 61.55 57.57 60.1 58.7 58.79 58.79 1028.09 1042.56 1008.61 908.6766667 1026.42 0.103929045 0.164227879 03013///Nucleocytoplasmic transport "GO:0000346///transcription export complex+++GO:0000347///THO complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck" GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport 66233 66233 'Dmap1' mRNA 684 670 733 26.26 24.97 29.86 22.95 23.33 25.31 27.03 23.86333333 688 687 736 695.6666667 703.6666667 0.994331311 0.00242065 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035267///NuA4 histone acetyltransferase complex GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0040008///regulation of growth+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043486///histone exchange+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045471///response to ethanol+++GO:0045892///negative regulation of transcription, DNA-templated" 66234 66234 'Msmo1' mRNA 3374 3368 3554 105.77 104.27 118.46 42.59 45.49 44.19 109.5 44.09 1550 1602 1543 3432 1565 2.40E-52 -1.146573081 00100///Steroid biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000254///C-4 methylsterol oxidase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0016126///sterol biosynthetic process 66235 66235 'Eif1ax' mRNA 1231 1350 1320 13.53 14.59 15.39 15.04 14.61 14.5 14.50333333 14.71666667 1575 1495 1471 1300.333333 1513.666667 0.019740179 0.206005838 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity GO:0006412///translation+++GO:0006413///translational initiation 66237 66237 'Atp6v1g2' mRNA 161 166.58 151.19 6.37 6.43 6.33 3.85 3.88 4.09 6.376666667 3.94 112.47 112.04 115.36 159.59 113.29 0.020569813 -0.506227755 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0042470///melanosome "GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 66240 66240 'Kcne1l' mRNA 17 20 21 0.7 0.81 0.92 0.97 1.03 0.92 0.81 0.973333333 27 28 25 19.33333333 26.66666667 0.456298468 0.449934537 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization GO:0006811///ion transport+++GO:0008016///regulation of heart contraction+++GO:0060048///cardiac muscle contraction+++GO:0060306///regulation of membrane repolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0071805///potassium ion transmembrane transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0097623///potassium ion export across plasma membrane+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:2001257///regulation of cation channel activity 66241 66241 'Tmem9' mRNA 1627 1684 1417 66.12 67.46 61.1 61.98 60.97 61.05 64.89333333 61.33333333 1754 1682 1669 1576 1701.666667 0.233695297 0.101427209 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0032585///multivesicular body membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0007042///lysosomal lumen acidification+++GO:0015031///protein transport+++GO:0042176///regulation of protein catabolic process+++GO:0048388///endosomal lumen acidification+++GO:0070070///proton-transporting V-type ATPase complex assembly+++GO:0090263///positive regulation of canonical Wnt signaling pathway 66242 66242 'Mrps16' mRNA 640 574 595 71.92 64.12 70.96 71.03 85.18 78.46 69 78.22333333 722 842 769 603 777.6666667 0.002526713 0.356102318 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 66244 66244 'Nemf' mRNA 1748 1790 1806 31.17 31.53 33.53 29.83 29.33 29.78 32.07666667 29.64666667 1950 1872 1880 1781.333333 1900.666667 0.367201372 0.080344043 GO:0005634///nucleus+++GO:1990112///RQC complex GO:0000049///tRNA binding+++GO:0043023///ribosomal large subunit binding GO:0051168///nuclear export+++GO:0072344///rescue of stalled ribosome+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process 66245 66245 'Hspbp1' mRNA 1071 1190 1130 41.3 45.52 46.06 41.15 44.4 43.4 44.29333333 42.98333333 1221 1287 1247 1130.333333 1251.666667 0.174047201 0.135510464 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0031625///ubiquitin protein ligase binding GO:0031398///positive regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity 66246 66246 'Osgep' mRNA 1050 1055 907 38.2 37.84 35 41.45 41.33 44.47 37.01333333 42.41666667 1309 1274 1359 1004 1314 8.64E-06 0.378958522 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0046872///metal ion binding+++GO:0061711///N(6)-L-threonylcarbamoyladenine synthase activity" GO:0002949///tRNA threonylcarbamoyladenosine modification+++GO:0008033///tRNA processing 66248 66248 'Alg5' mRNA 677.26 674.23 755.83 25.29 25.04 29.36 41.17 43.43 41.79 26.56333333 42.13 1226.14 1262.15 1208.94 702.44 1232.41 2.77E-15 0.796886712 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004581///dolichyl-phosphate beta-glucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0007368///determination of left/right symmetry 66249 66249 'Pno1' mRNA 434 451 481 16.28 16.69 19.15 32.33 32.9 31.09 17.37333333 32.10666667 990 983 921 455.3333333 964.6666667 1.65E-23 1.069149017 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0008150///biological_process 66251 66251 'Arfgap3' mRNA 741 675 736 15.68 14.06 16.54 18.02 18.6 18.04 15.42666667 18.22 979 988 949 717.3333333 972 3.24E-05 0.424918724 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0045202///synapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030100///regulation of endocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048205///COPI coating of Golgi vesicle+++GO:0050790///regulation of catalytic activity 66253 66253 'Aig1' mRNA 1984.27 2066.55 1655.25 72.36 76 64.41 49.45 47.58 50.6 70.92333333 49.21 1509.48 1440.24 1516.46 1902.023333 1488.726667 5.78E-06 -0.361600603 GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0042758///long-chain fatty acid catabolic process 66254 66254 'Dimt1' mRNA 413.5 494.39 460.82 7.32 8.72 8.99 6.99 7.52 7.39 8.343333333 7.3 419.4 430.01 433.76 456.2366667 427.7233333 0.515133366 -0.104476808 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol "GO:0000179///rRNA (adenine-N6,N6-)-dimethyltransferase activity+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0052909///18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity" GO:0000154///rRNA modification+++GO:0006364///rRNA processing+++GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:2000234///positive regulation of rRNA processing 66255 66255 'Hsbp1l1' mRNA 23 21 18 0.92 0.76 0.77 0.25 0.56 0.44 0.816666667 0.416666667 8 14 11 20.66666667 11 0.182134188 -0.914590176 04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0003714///transcription corepressor activity "GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070370///cellular heat acclimation" 66256 66256 'Ssr2' mRNA 1715 1772 1809 101.26 103.8 113.67 143.55 165.65 136.42 106.2433333 148.54 2773 3125 2557 1765.333333 2818.333333 1.06E-13 0.66248584 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001701///in utero embryonic development 66257 66257 'Nicn1' mRNA 1253 1325 1242 33.46 34.85 35.18 20.65 23.67 22.39 34.49666667 22.23666667 889 995 933 1273.333333 939 8.99E-07 -0.449891202 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule GO:0003674///molecular_function GO:0008150///biological_process+++GO:0018095///protein polyglutamylation 66258 66258 'Mrps17' mRNA 1062 1049 996 50.55 47.65 48.48 49.25 50.26 55.36 48.89333333 51.62333333 1146 1146 1230 1035.666667 1174 0.068900045 0.169936744 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0006412///translation+++GO:0032543///mitochondrial translation 66259 66259 'Camk2n1' mRNA 375 281 287 5.63 4.15 4.57 2.68 2.11 2.84 4.783333333 2.543333333 205 158 211 314.3333333 191.3333333 7.53E-05 -0.728174154 GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse GO:0004860///protein kinase inhibitor activity+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0019901///protein kinase binding GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006469///negative regulation of protein kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0043086///negative regulation of catalytic activity+++GO:0045786///negative regulation of cell cycle+++GO:0045861///negative regulation of proteolysis+++GO:0055074///calcium ion homeostasis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity 66260 66260 'Tmem54' mRNA 4 5 6 0.23 0.3 0.38 1.89 1.64 2.3 0.303333333 1.943333333 38 31 45 5 38 2.61E-06 2.910627905 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66261 66261 'Tm4sf20' mRNA 3 2 1 0.13 0.09 0.05 0.04 0.16 0.04 0.09 0.08 1 4 1 2 2 0.998591786 0.011087892 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0045861///negative regulation of proteolysis 66262 66262 'Ing5' mRNA 682 653 813 8.06 7.59 10.18 6.21 5.79 6.37 8.61 6.123333333 605 552 601 716 586 0.023940738 -0.307151803 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0003682///chromatin binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding "GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006473///protein acetylation+++GO:0008285///negative regulation of cell proliferation+++GO:0016573///histone acetylation+++GO:0043065///positive regulation of apoptotic process+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045926///negative regulation of growth+++GO:2001235///positive regulation of apoptotic signaling pathway" 66264 66264 'Ccdc28b' mRNA 418 480 402 31.74 35.86 32.67 27.43 28.27 26.11 33.42333333 27.27 412 419 373 433.3333333 401.3333333 0.442579272 -0.120298879 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 66266 66266 'Eapp' mRNA 1339.82 1207.13 1282.57 25.69 23.15 25.3 29.55 28.59 29.19 24.71333333 29.11 1674.47 1623.85 1664.04 1276.506667 1654.12 1.92E-05 0.360960576 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008284///positive regulation of cell proliferation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter 66268 66268 'Pigyl' mRNA 543 491 488 56.33 50.59 53.73 45.29 46.18 47.52 53.55 46.33 499 495 505 507.3333333 499.6666667 0.847849845 -0.033345487 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0006506///GPI anchor biosynthetic process 66270 66270 'Retreg1' mRNA 1642 1744 1287 29.14 30.07 25.01 25.64 23.45 26.3 28.07333333 25.13 1601 1446 1589 1557.666667 1545.333333 0.878842174 -0.018239189 GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003674///molecular_function GO:0000423///mitophagy+++GO:0006914///autophagy+++GO:0019233///sensory perception of pain+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050872///white fat cell differentiation+++GO:0061709///reticulophagy 66271 66271 'Tmem126a' mRNA 506 575 565 45.11 50.83 53.45 60.92 69.7 66.34 49.79666667 65.65333333 782 871 822 548.6666667 825 3.98E-07 0.576521016 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0021554///optic nerve development+++GO:0032981///mitochondrial respiratory chain complex I assembly 66272 66272 'Cox16' mRNA 672.1 713.52 759.33 36.12 35.48 45.9 33.29 34.16 32.93 39.16666667 33.46 813.76 765.98 751.43 714.9833333 777.0566667 0.421493159 0.104532139 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 66273 66273 'Aamdc' mRNA 1001 999 1052 82.24 81.14 91.74 57.52 67.54 60.96 85.04 62.00666667 813 922 818 1017.333333 851 0.013197123 -0.270223723 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0043066///negative regulation of apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 66274 66274 'Lyrm9' mRNA 996.34 1042.01 947.72 10.53 10.83 10.62 6.17 6.24 6.55 10.66 6.32 672.53 664.35 691 995.3566667 675.96 7.16E-10 -0.56903283 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66276 66276 '1810009A15Rik' mRNA 635 640 630 71.35 71.5 75.14 93.6 112.39 97.33 72.66333333 101.1066667 951.32 1111 954 635 1005.44 1.08E-09 0.65208494 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66277 66277 'Klf15' mRNA 1736 1793 1018 38.45 38.63 23.31 15.01 24.67 20.97 33.46333333 20.21666667 807 1246 1068 1515.666667 1040.333333 0.092814327 -0.537738427 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001678///cellular glucose homeostasis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010001///glial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0030111///regulation of Wnt signaling pathway+++GO:0032868///response to insulin+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046326///positive regulation of glucose import+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:1901653///cellular response to peptide+++GO:2000757///negative regulation of peptidyl-lysine acetylation" 66278 66278 'Smim20' mRNA 1377 1397 1345 93.39 93.74 96.79 101.66 92.72 87.82 94.64 94.06666667 1718 1527 1434 1373 1559.666667 0.060212552 0.170925274 GO:0005576///extracellular region+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 66279 66279 'Tmem218' mRNA 814 846 884 47.76 49.39 54.79 20.6 20.54 22.36 50.64666667 21.16666667 394 386 414 848 398 4.99E-23 -1.10516027 GO:0005575///cellular_component+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 66282 66282 'Tma16' mRNA 95 76 65 5.27 4.14 3.84 7.53 6.52 5.69 4.416666667 6.58 156 132 114 78.66666667 134 0.003756441 0.758802461 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 66284 66284 'Gkn2' mRNA 1 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0045178///basal part of cell GO:0003674///molecular_function GO:0009617///response to bacterium+++GO:0042127///regulation of cell proliferation 66286 66286 'Sec11c' mRNA 2194 2233 2268 195.81 197.31 214.91 288.91 282.67 286.2 202.6766667 285.9266667 3703 3522 3538 2231.666667 3587.666667 6.35E-24 0.671496328 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis 66290 66290 'Atp6v1g1' mRNA 5782 6013 5813 331.28 340.47 353.39 312.73 337.1 319.23 341.7133333 323.02 6261 6580 6178 5869.333333 6339.666667 0.146152242 0.099542326 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0005622///intracellular+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex" "GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0051117///ATPase binding" GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0036295///cellular response to increased oxygen levels+++GO:1902600///proton transmembrane transport 66291 66291 'Smim8' mRNA 389 362 340 36.57 33.64 34.46 32.03 30.23 32.85 34.89 31.70333333 389 363 382 363.6666667 378 0.809260148 0.044847382 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66292 66292 'Mrps21' mRNA 773 820 879 138.59 147.16 167.39 153.19 171.61 156.98 151.0466667 160.5933333 971 1055 957 824 994.3333333 0.022875022 0.257214348 03010///Ribosome GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 66294 66294 'Fam3a' mRNA 1566 1644 1502 48.46 49.99 48.82 34.47 37.2 39.63 49.09 37.1 1294 1334 1405 1570.666667 1344.333333 0.004648785 -0.234833931 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0019732///antifungal humoral response+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046890///regulation of lipid biosynthetic process+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1905035///negative regulation of antifungal innate immune response 66296 66296 'Haus2' mRNA 447.56 427.43 417.75 7.96 7.46 7.87 7.58 6.75 7.51 7.763333333 7.28 491.64 428.07 471.8 430.9133333 463.8366667 0.538988438 0.094163056 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function GO:0007020///microtubule nucleation+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0031023///microtubule organizing center organization+++GO:0051225///spindle assembly+++GO:0051301///cell division 66300 66300 'Inafm1' mRNA 454.89 438.76 360.51 15.74 14.97 13.24 9.1 15.44 12.33 14.65 12.29 302.19 500.26 395.97 418.0533333 399.4733333 0.779347877 -0.068025064 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005246///calcium channel regulator activity GO:0008150///biological_process 66302 66302 'Rmdn1' mRNA 430 436 405 13.15 13.14 13.14 9.74 9.76 11.19 13.14333333 10.23 366 358 407 423.6666667 377 0.22241108 -0.179134963 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0097431///mitotic spindle pole GO:0008017///microtubule binding GO:0008150///biological_process 66306 66306 'Fam53c' mRNA 1334 1320 1309 16.56 16.09 17.19 14.34 13.86 14.65 16.61333333 14.28333333 1333 1269 1320 1321 1307.333333 0.809260148 -0.02745861 GO:0005634///nucleus GO:0003674///molecular_function GO:0006606///protein import into nucleus 66307 66307 'Isoc1' mRNA 940 956 470 20.39 20.42 10.82 9 9.23 8.08 17.21 8.77 477 478 415 788.6666667 456.6666667 0.01431707 -0.784853586 GO:0005737///cytoplasm+++GO:0005777///peroxisome GO:0003674///molecular_function GO:0008150///biological_process 66308 66308 'Mplkip' mRNA 349.85 310.74 155.36 7.23 6.33 3.41 2.6 3.18 4.1 5.656666667 3.293333333 144.59 173.02 220.59 271.9833333 179.4 0.02421738 -0.594915839 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0051301///cell division 66309 66309 'Tmem128' mRNA 813 803 830 39.9 39.15 42.86 50.79 49.51 48.61 40.63666667 49.63666667 1182 1116 1085 815.3333333 1127.666667 1.02E-06 0.45437466 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66310 66310 'Dpy30' mRNA 923 875 816 93.32 87.68 87.46 88.25 85.67 83.17 89.48666667 85.69666667 1000 948 911 871.3333333 953 0.259931619 0.118277771 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex" GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006325///chromatin organization+++GO:0006348///chromatin silencing at telomere+++GO:0016197///endosomal transport+++GO:0031509///telomeric heterochromatin assembly+++GO:0051568///histone H3-K4 methylation 66311 66311 'Cenpw' mRNA 260 261 288 12.21 13.32 14.6 14.79 15.07 12.58 13.37666667 14.14666667 333 361 311 269.6666667 335 0.074190672 0.299096584 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016363///nuclear matrix" GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051382///kinetochore assembly 66313 66313 'Smurf2' mRNA 653 624 733 7.19 6.75 8.56 7.19 6.26 7.22 7.5 6.89 750 643 734 670 709 0.688016269 0.064664483 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0045121///membrane raft GO:0004842///ubiquitin-protein transferase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:1901165///positive regulation of trophoblast cell migration 66314 66314 'Tpd52l2' mRNA 2439 2352 2503 62.08 60.88 58.49 63.48 62.19 68.81 60.48333333 64.82666667 3022 2862 2907 2431.333333 2930.333333 6.44E-04 0.255146526 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0042803///protein homodimerization activity GO:0005975///carbohydrate metabolic process+++GO:0008150///biological_process 66315 66315 'Senp7' mRNA 929 973.6 866.5 9.66 9.85 10.21 5.64 5.19 4.83 9.906666667 5.22 611.56 558.87 557.35 923.0333333 575.9266667 6.46E-13 -0.692379981 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0070139///SUMO-specific endopeptidase activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation 66317 66317 'Wdr61' mRNA 1304 1369 1316 63.01 65.12 67.29 69.85 75.42 71.76 65.14 72.34333333 1654 1745 1647 1329.666667 1682 5.87E-05 0.327669074 03018///RNA degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016593///Cdc73/Paf1 complex+++GO:0035327///transcriptionally active chromatin+++GO:0055087///Ski complex GO:0005515///protein binding GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016055///Wnt signaling pathway+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0051568///histone H3-K4 methylation+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation+++GO:2001162///positive regulation of histone H3-K79 methylation 66320 66320 'Tmem208' mRNA 1184 1099 1135 105.74 96.67 107.51 139.99 144.16 137.16 103.3066667 140.4366667 1781 1784 1681 1139.333333 1748.666667 1.09E-13 0.60555645 GO:0005773///vacuole+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006624///vacuolar protein processing+++GO:0006914///autophagy 66322 66322 'Krt88' mRNA 0 1 2 0 0.07 0.12 0 0 0 0.063333333 0 0 0 0 1 0 0.596502362 -2.487866303 GO:0005575///cellular_component+++GO:0005882///intermediate filament GO:0003674///molecular_function GO:0008150///biological_process 66323 66323 '1700001K19Rik' mRNA 7 6 0 0.27 0.22 0 0.19 0.16 0.13 0.163333333 0.16 6 5 4 4.333333333 5 0.887329349 0.222695653 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66326 66326 'Dnajc5b' mRNA 1002 1003 934 64.57 63.94 63.96 4.84 4.66 4.05 64.15666667 4.516666667 84 79 74 979.6666667 79 4.05E-153 -3.643693877 04141///Protein processing in endoplasmic reticulum GO:0005575///cellular_component+++GO:0016020///membrane GO:0008150///biological_process 66328 66328 'Scp2d1' mRNA 1 1 0 0.09 0.09 0 0.16 0 0.08 0.06 0.08 2 0 1 0.666666667 1 0.866127206 0.585499383 GO:0005575///cellular_component GO:0032934///sterol binding GO:0006694///steroid biosynthetic process+++GO:0015914///phospholipid transport+++GO:0032385///positive regulation of intracellular cholesterol transport 66329 66329 'Susd3' mRNA 445 489 390 18.76 20.27 17.51 24.36 27.26 24.42 18.84666667 25.34666667 664 723 640 441.3333333 675.6666667 3.01E-07 0.606721428 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66330 66330 '1700020L24Rik' mRNA 11.47 13.61 3.61 0.8 0.9 0.27 0.69 0.26 0.3 0.656666667 0.416666667 11.34 4.1 4.78 9.563333333 6.74 0.685677208 -0.506187892 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66333 66333 'Aqp11' mRNA 277 280 252 12.64 12.61 12.2 8.5 8.31 7.85 12.48333333 8.22 214 204 191 269.6666667 203 0.012452947 -0.420403451 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0015250///water channel activity+++GO:0015254///glycerol channel activity+++GO:0015267///channel activity+++GO:0042802///identical protein binding GO:0001822///kidney development+++GO:0006612///protein targeting to membrane+++GO:0006833///water transport+++GO:0008284///positive regulation of cell proliferation+++GO:0009992///cellular water homeostasis+++GO:0015793///glycerol transport+++GO:0030104///water homeostasis+++GO:0032364///oxygen homeostasis+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0048388///endosomal lumen acidification+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0072014///proximal tubule development+++GO:0080170///hydrogen peroxide transmembrane transport+++GO:1903573///negative regulation of response to endoplasmic reticulum stress+++GO:1904293///negative regulation of ERAD pathway 66335 66335 'Atp6v1c1' mRNA 1857 2044 2068 50.15 54.37 59.25 72.87 76.44 74 54.59 74.43666667 3102 3176 3049 1989.666667 3109 3.46E-16 0.630519258 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0045177///apical part of cell" "GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 66336 66336 'Cenpp' mRNA 35.53 29.41 30.99 1.24 1.37 1.26 1.88 2.17 1.66 1.29 1.903333333 59.44 48.32 63.06 31.97666667 56.94 0.031728166 0.842261008 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus" GO:0003674///molecular_function GO:0008150///biological_process+++GO:0034080///CENP-A containing nucleosome assembly 66337 66337 'Fam229b' mRNA 198 200 187 18.47 18.53 19.36 10.87 11.32 11.57 18.78666667 11.25333333 127 133 130 195 130 0.002555792 -0.595601197 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66338 66338 'Cdrt4' mRNA 18 16 19 1.76 1.55 1.97 1.62 2.11 1.42 1.76 1.716666667 19 24 16 17.66666667 19.66666667 0.863090843 0.141457001 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66340 66340 'Psenen' mRNA 1918 1902 1900 209.14 205.73 219.38 223.1 268.27 225.29 211.4166667 238.8866667 2336 2733 2277 1906.666667 2448.666667 1.04E-04 0.349838385 04330///Notch signaling pathway+++05010///Alzheimer disease GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:0070765///gamma-secretase complex+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0061133///endopeptidase activator activity GO:0006509///membrane protein ectodomain proteolysis+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0034205///amyloid-beta formation+++GO:0042982///amyloid precursor protein metabolic process+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043085///positive regulation of catalytic activity 66341 66341 'Eid3' mRNA 17 6 13 0.79 0.27 0.64 0.52 0.46 0.25 0.566666667 0.41 13 11 6 12 10 0.78902271 -0.283163118 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030915///Smc5-Smc6 complex" GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus 66343 66343 'Tmem177' mRNA 326 370 361 5.36 5.99 6.3 4.09 4.99 5.21 5.883333333 4.763333333 286 341 353 352.3333333 326.6666667 0.525983639 -0.120284162 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0003674///molecular_function GO:0008150///biological_process 66346 66346 '1700029P11Rik' mRNA 0 0 1 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 66349 66349 'Dmac2' mRNA 651 676 664 22.64 24.13 25.22 16.29 17.52 18.43 23.99666667 17.41333333 496 538 542 663.6666667 525.3333333 0.002677363 -0.348754741 GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0019005///SCF ubiquitin ligase complex GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0032981///mitochondrial respiratory chain complex I assembly 66350 66350 'Pla2g12a' mRNA 295 341 204 11.06 12.63 8.11 8.28 7.42 8.63 10.6 8.11 253 221 255 280 243 0.327861079 -0.208031716 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005576///extracellular region+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus "GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0050482///arachidonic acid secretion 66352 66352 'Blzf1' mRNA 738 794 805 10.03 10.65 11.59 6.65 6.62 6.76 10.75666667 6.676666667 563 548 561 779 557.3333333 5.03E-06 -0.496576315 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043001///Golgi to plasma membrane protein transport 66353 66353 'Riiad1' mRNA 26 41 29 1.66 2.85 2.34 0.47 0.73 0.85 2.283333333 0.683333333 12 28 14 32 18 0.155517384 -0.832054625 GO:0005575///cellular_component GO:0008150///biological_process 66354 66354 'Snw1' mRNA 2538 2546 2454 63.23 62.47 64.86 50.16 50.33 50.85 63.52 50.44666667 2315 2268 2272 2512.666667 2285 0.033017466 -0.148815908 03040///Spliceosome+++04330///Notch signaling pathway+++05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071141///SMAD protein complex GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0019899///enzyme binding+++GO:0035257///nuclear hormone receptor binding+++GO:0042809///vitamin D receptor binding+++GO:0042974///retinoic acid receptor binding+++GO:0046332///SMAD binding+++GO:0050681///androgen receptor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0014010///Schwann cell proliferation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0035914///skeletal muscle cell differentiation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043923///positive regulation by host of viral transcription+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0048385///regulation of retinoic acid receptor signaling pathway+++GO:0050769///positive regulation of neurogenesis+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0070562///regulation of vitamin D receptor signaling pathway+++GO:0070564///positive regulation of vitamin D receptor signaling pathway+++GO:0071300///cellular response to retinoic acid" 66355 66355 'Gmpr' mRNA 341 358 365 13.21 14.36 15.28 12.91 14.24 13.63 14.28333333 13.59333333 400 401 411 354.6666667 404 0.250528605 0.174966636 00230///Purine metabolism GO:1902560///GMP reductase complex GO:0003824///catalytic activity+++GO:0003920///GMP reductase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding GO:0006144///purine nucleobase metabolic process+++GO:0006163///purine nucleotide metabolic process+++GO:0009117///nucleotide metabolic process+++GO:0032264///IMP salvage 66356 66356 'Knop1' mRNA 2293.97 2380.24 2294.13 22.9 23.3 24.24 18.86 18.36 19.37 23.48 18.86333333 2182.96 2069.64 2172.17 2322.78 2141.59 0.082420216 -0.129584513 GO:0005634///nucleus+++GO:0005730///nucleolus 66357 66357 'Ostc' mRNA 2340 2231 2369 138.88 130.88 149.18 228.52 222.36 228.34 139.6466667 226.4066667 4416 4189 4265 2313.333333 4290 2.06E-38 0.87706704 GO:0005783///endoplasmic reticulum+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006486///protein glycosylation+++GO:0008150///biological_process 66358 66358 'Adprm' mRNA 456 504 460 19.22 21.55 20.6 16.81 15.3 15.13 20.45666667 15.74666667 450 401 392 473.3333333 414.3333333 0.136744802 -0.204247347 00230///Purine metabolism+++00564///Glycerophospholipid metabolism GO:0005575///cellular_component "GO:0008663///2',3'-cyclic-nucleotide 2'-phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0047631///ADP-ribose diphosphatase activity+++GO:0047734///CDP-glycerol diphosphatase activity" GO:0008150///biological_process 66359 66359 'Cox20' mRNA 533.56 477.47 508 95.28 86.63 102.24 75.06 100.07 79.81 94.71666667 84.98 443.11 586.66 460.3 506.3433333 496.69 0.859124538 -0.038445226 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 66361 66361 'Zfand1' mRNA 554 524 490 19.95 18.44 18.63 13.84 15.42 14.33 19.00666667 14.53 442 483 442 522.6666667 455.6666667 0.114442019 -0.207733352 GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0070628///proteasome binding GO:0035617///stress granule disassembly+++GO:0090316///positive regulation of intracellular protein transport+++GO:1903843///cellular response to arsenite ion 66362 66362 'Exosc3' mRNA 516 459 477 30.55 26.86 29.97 35.43 36.59 35.09 29.12666667 35.70333333 673 691 657 484 673.6666667 5.09E-05 0.465085994 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045006///DNA deamination+++GO:0045190///isotype switching+++GO:0045830///positive regulation of isotype switching+++GO:0071034///CUT catabolic process+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071049///nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing" 66364 66364 'Pigbos1' mRNA 155 174 209 26.36 29.6 37.74 25.13 29.76 30.01 31.23333333 28.3 168 193 193 179.3333333 184.6666667 0.924637684 0.026149578 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:1900101///regulation of endoplasmic reticulum unfolded protein response 66365 66365 'Ccdc90b' mRNA 818 857 857 30.6 31.87 33.72 29.57 29.24 31.82 32.06333333 30.21 921 886 956 844 921 0.31311612 0.113069623 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process 66366 66366 'Ergic3' mRNA 4795 4782 4782 205.3 202.05 217.18 205.23 204 205.66 208.1766667 204.9633333 5497 5331 5329 4786.333333 5385.666667 0.011108133 0.157389679 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0016192///vesicle-mediated transport" 66367 66367 '2310022A10Rik' mRNA 488 576 495 10.36 11.97 11.16 13.22 13.41 12.3 11.16333333 12.97666667 720 709 647 519.6666667 692 4.93E-04 0.402588866 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 66368 66368 'Rtca' mRNA 837 878 807 31.7 32.72 32.49 31.93 31.43 32.92 32.30333333 32.09333333 967 934 967 840.6666667 956 0.073177841 0.174382905 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0003963///RNA-3'-phosphate cyclase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006396///RNA processing 66369 66369 'Dus2' mRNA 418.98 390.74 384.73 10.89 9.86 10.34 11.4 12.39 12.07 10.36333333 11.95333333 487.29 521.88 490.34 398.15 499.8366667 0.014050145 0.318788477 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003824///catalytic activity+++GO:0004860///protein kinase inhibitor activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0017150///tRNA dihydrouridine synthase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0070402///NADPH binding+++GO:0102264///tRNA-dihydrouridine20 synthase activity GO:0002943///tRNA dihydrouridine synthesis+++GO:0008033///tRNA processing+++GO:0043086///negative regulation of catalytic activity+++GO:0060548///negative regulation of cell death 66371 66371 'Chmp4c' mRNA 61 73 50 1.97 2.32 1.71 2.64 2.13 2.14 2 2.303333333 94 74 74 61.33333333 80.66666667 0.251538307 0.386924916 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0090543///Flemming body GO:0042803///protein homodimerization activity GO:0006900///vesicle budding from membrane+++GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0009838///abscission+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032466///negative regulation of cytokinesis+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0044878///mitotic cytokinesis checkpoint+++GO:0046761///viral budding from plasma membrane+++GO:0050792///regulation of viral process+++GO:0061952///midbody abscission+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902188///positive regulation of viral release from host cell 66373 66373 'Lsm5' mRNA 203 174 194 34.3 29.4 34.8 40.41 45.34 44.64 32.83333333 43.46333333 272 296 289 190.3333333 285.6666667 8.81E-04 0.573410583 03018///RNA degradation+++03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005737///cytoplasm+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0120115///Lsm2-8 complex+++GO:1990726///Lsm1-7-Pat1 complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0008380///RNA splicing+++GO:0009617///response to bacterium" 66374 66374 '2310011J03Rik' mRNA 1415 1534 1514 49.68 53.1 56.39 51.27 54.51 50.52 53.05666667 52.1 1678 1741 1600 1487.666667 1673 0.087705301 0.156793533 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66375 66375 'Dhrs7' mRNA 1533 1495 1369 71.09 68.36 67.31 79.99 88.32 77.09 68.92 81.8 1982 2133 1847 1465.666667 1987.333333 1.61E-07 0.429555482 GO:0016491///oxidoreductase activity GO:0008150///biological_process 66377 66377 'Ndufc1' mRNA 1249 1270 1441 254.5 262.68 313.48 254.83 303.26 257.97 276.8866667 272.02 1403 1666 1370 1320 1479.666667 0.234583469 0.150286071 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 66379 66379 'Cox14' mRNA 1910 1878 1877 186.46 181.97 194.47 192.52 200.98 198.36 187.6333333 197.2866667 2255 2291 2242 1888.333333 2262.666667 7.23E-04 0.248792602 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 66381 66381 'Rnf113a2' mRNA 340 318 327 14.77 13.63 15.07 13.69 15.47 16.3 14.49 15.15333333 362 399 417 328.3333333 392.6666667 0.107924465 0.246809566 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005684///U2-type spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0016567///protein ubiquitination+++GO:0018276///isopeptide cross-linking via N6-glycyl-L-lysine+++GO:0034247///snoRNA splicing+++GO:0070100///negative regulation of chemokine-mediated signaling pathway" 66383 66383 'Iscu' mRNA 2137 2398 2122 152.53 169.71 161.49 157.71 173.48 170.11 161.2433333 167.1 2555 2734 2662 2219 2650.333333 0.001156132 0.246390274 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol "GO:0005506///iron ion binding+++GO:0008198///ferrous iron binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0060090///molecular adaptor activity" "GO:0006879///cellular iron ion homeostasis+++GO:0016226///iron-sulfur cluster assembly+++GO:1902958///positive regulation of mitochondrial electron transport, NADH to ubiquinone+++GO:1904234///positive regulation of aconitate hydratase activity+++GO:1904439///negative regulation of ferrous iron import across plasma membrane" 66384 66384 'Srp19' mRNA 970 909 889 73.59 68.31 71.59 85.92 88.52 88.07 71.16333333 87.50333333 1296 1301 1281 922.6666667 1292.666667 2.46E-08 0.475202026 03060///Protein export "GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0048500///signal recognition particle" GO:0003723///RNA binding+++GO:0008312///7S RNA binding+++GO:0043022///ribosome binding "GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006617///SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition" 66385 66385 'Ppp1r7' mRNA 1461.19 1324.99 1375.35 21.58 19.21 21.5 17.4 17.95 16.84 20.76333333 17.39666667 1359.36 1367.71 1272.61 1387.176667 1333.226667 0.51328338 -0.069816733 GO:0005634///nucleus+++GO:0005694///chromosome GO:0005515///protein binding GO:0007059///chromosome segregation+++GO:0035307///positive regulation of protein dephosphorylation 66387 66387 'Nudt8' mRNA 186 207 177 16.21 17.89 16.37 17.75 18.85 17.99 16.82333333 18.19666667 233 241 228 190 234 0.118928574 0.290875724 GO:0005739///mitochondrion GO:0000287///magnesium ion binding+++GO:0010945///CoA pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0015938///coenzyme A catabolic process+++GO:0036114///medium-chain fatty-acyl-CoA catabolic process+++GO:0044580///butyryl-CoA catabolic process+++GO:0046356///acetyl-CoA catabolic process+++GO:1901289///succinyl-CoA catabolic process+++GO:1902859///propionyl-CoA catabolic process+++GO:2001294///malonyl-CoA catabolic process 66388 66388 'Cutc' mRNA 163 179 208 7.58 8.2 10.22 10.54 10.74 9.19 8.666666667 10.15666667 261 259 220 183.3333333 246.6666667 0.038676152 0.411488413 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005507///copper ion binding+++GO:0046872///metal ion binding GO:0051262///protein tetramerization+++GO:0055070///copper ion homeostasis 66390 66390 'Prelid3b' mRNA 740 756 764 31.87 32.12 34.91 56.59 54.27 52.07 32.96666667 54.31 1509 1412 1343 753.3333333 1421.333333 2.39E-24 0.902510785 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:1990050///phosphatidic acid transporter activity GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer 66394 66394 'Nosip' mRNA 1518 1614 1427 46.68 48.79 46.91 44.08 43.94 43.85 47.46 43.95666667 1641 1606 1590 1519.666667 1612.333333 0.394225068 0.075056252 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043086///negative regulation of catalytic activity+++GO:0051001///negative regulation of nitric-oxide synthase activity 66395 66395 'Ahnak' mRNA 3775 3920 3613 19.92 20.9 19.98 36.29 35.6 38.15 20.26666667 36.68 7834 7133 7660 3769.333333 7542.333333 7.64E-75 0.989051548 05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0015629///actin cytoskeleton+++GO:0030315///T-tubule+++GO:0031982///vesicle+++GO:0042383///sarcolemma+++GO:0043034///costamere+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044548///S100 protein binding+++GO:0097493///structural molecule activity conferring elasticity GO:0043484///regulation of RNA splicing+++GO:1901385///regulation of voltage-gated calcium channel activity 66396 66396 'Ccdc82' mRNA 1462.72 1430.05 1380.11 15.85 15.29 16.07 11.75 11.49 11.97 15.73666667 11.73666667 1243.17 1175.7 1216.81 1424.293333 1211.893333 0.002520943 -0.245191992 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 66397 66397 'Sar1b' mRNA 1863 1891 1824 90.56 90.76 94.07 102.53 103.25 109.22 91.79666667 105 2421 2378 2494 1859.333333 2431 5.92E-08 0.375029175 04141///Protein processing in endoplasmic reticulum+++05134///Legionellosis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0032580///Golgi cisterna membrane+++GO:0070971///endoplasmic reticulum exit site GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0003400///regulation of COPII vesicle coating+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016050///vesicle organization+++GO:0016192///vesicle-mediated transport+++GO:0061024///membrane organization+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum 66398 66398 'Commd5' mRNA 507 530 565 28.86 28.97 33.58 32.42 30.34 38.25 30.47 33.67 658 602 742 534 667.3333333 0.018792178 0.307057483 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0030307///positive regulation of cell growth+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0072158///proximal tubule morphogenesis 66399 66399 'Tsfm' mRNA 376 375 351 19.64 19.34 19.45 25.8 30.05 26.08 19.47666667 27.31 567 644 554 367.3333333 588.3333333 8.68E-08 0.669646073 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003746///translation elongation factor activity GO:0006412///translation+++GO:0006414///translational elongation+++GO:0070125///mitochondrial translational elongation+++GO:0070129///regulation of mitochondrial translation 66400 66400 'Alkbh7' mRNA 624 594 523 43.48 40.9 38.67 33.27 35.79 35.37 41.01666667 34.81 549 573 561 580.3333333 561 0.701393626 -0.057791388 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006631///fatty acid metabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010883///regulation of lipid storage+++GO:0012501///programmed cell death+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death 66401 66401 'Nudt2' mRNA 545 523 527 42.72 40.74 43.64 36.6 39.9 36.5 42.36666667 37.66666667 533 570 514 531.6666667 539 0.961944002 0.00805918 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0004081///bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity+++GO:0005525///GTP binding+++GO:0008796///bis(5'-nucleosyl)-tetraphosphatase activity+++GO:0016787///hydrolase activity GO:0006167///AMP biosynthetic process+++GO:0006754///ATP biosynthetic process+++GO:0006915///apoptotic process 66402 66402 'Sln' mRNA 3 1 1 0.48 0.16 0.17 0 0 0 0.27 0 0 0 0 1.666666667 0 0.334169217 -3.181769893 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane GO:0005515///protein binding+++GO:0030234///enzyme regulator activity GO:0050790///regulation of catalytic activity+++GO:0051924///regulation of calcium ion transport+++GO:0070296///sarcoplasmic reticulum calcium ion transport+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901077///regulation of relaxation of muscle+++GO:1901877///negative regulation of calcium ion binding+++GO:1901894///regulation of calcium-transporting ATPase activity+++GO:1901895///negative regulation of calcium-transporting ATPase activity 66403 66403 'Asf1a' mRNA 595.3 603.74 464.85 15.32 15.3 12.69 13.09 13.51 13.06 14.43666667 13.22 584.94 589.55 564.95 554.63 579.8133333 0.725265943 0.056727663 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0001649///osteoblast differentiation+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0042692///muscle cell differentiation 66404 66404 'Rtf2' mRNA 1792 2000 1961 47.29 51.98 54.9 60.15 61.54 59.11 51.39 60.26666667 2621 2618 2493 1917.666667 2577.333333 1.10E-07 0.413507197 GO:0005634///nucleus+++GO:0005657///replication fork+++GO:0005694///chromosome GO:0003677///DNA binding GO:0071171///site-specific DNA replication termination at RTS1 barrier+++GO:0072711///cellular response to hydroxyurea+++GO:0097752///regulation of DNA stability+++GO:1902979///mitotic DNA replication termination 66405 66405 'Mcts2' mRNA 152 126 137 12.96 10.65 12.4 11.62 12.78 14.59 12.00333333 12.99666667 156 167 189 138.3333333 170.6666667 0.211296417 0.291465612 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding GO:0001731///formation of translation preinitiation complex+++GO:0002188///translation reinitiation+++GO:0032790///ribosome disassembly+++GO:0075522///IRES-dependent viral translational initiation 66406 66406 'Sac3d1' mRNA 292 312 325 12.71 13.43 14.94 14.79 15.36 14.75 13.69333333 14.96666667 390 397 377 309.6666667 388 0.037351817 0.31184086 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0005515///protein binding GO:0007049///cell cycle+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0050776///regulation of immune response+++GO:0051225///spindle assembly+++GO:0051298///centrosome duplication+++GO:0051301///cell division 66407 66407 'Mrps15' mRNA 638 587 509 44.2 40.24 37.42 53.14 50.94 52.19 40.62 52.09 879 821 834 578 844.6666667 2.32E-07 0.537968331 03010///Ribosome GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0006412///translation+++GO:0032543///mitochondrial translation 66408 66408 'Aptx' mRNA 935 1057 1026 8.67 9.7 10.21 6.83 6.4 6.08 9.526666667 6.436666667 833 764 717 1006 771.3333333 1.33E-04 -0.396913652 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003824///catalytic activity+++GO:0008967///phosphoglycolate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0030983///mismatched DNA binding+++GO:0033699///DNA 5'-adenosine monophosphate hydrolase activity+++GO:0046403///polynucleotide 3'-phosphatase activity+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0051219///phosphoprotein binding+++GO:0120108///DNA-3'-diphospho-5'-guanosine diphosphatase+++GO:1990165///single-strand break-containing DNA binding GO:0000012///single strand break repair+++GO:0006266///DNA ligation+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016311///dephosphorylation+++GO:0031647///regulation of protein stability+++GO:0042542///response to hydrogen peroxide+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0098506///polynucleotide 3' dephosphorylation 66409 66409 'Rsl1d1' mRNA 1351 1283 1274 42.23 39.52 42.25 43.78 45.16 41.03 41.33333333 43.32333333 1610 1621 1460 1302.666667 1563.666667 0.003485317 0.251544072 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030686///90S preribosome GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0048027///mRNA 5'-UTR binding GO:0000470///maturation of LSU-rRNA+++GO:0032880///regulation of protein localization+++GO:0042981///regulation of apoptotic process+++GO:2000772///regulation of cellular senescence 66410 66410 'Mterf3' mRNA 535.87 492.99 591.18 18.96 16.21 21.58 17.88 17.43 18.36 18.91666667 17.89 577.29 552.07 588.06 540.0133333 572.4733333 0.679620372 0.069580234 GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0061668///mitochondrial ribosome assembly" 66411 66411 'Tbcb' mRNA 1401 1486 1443.41 98.23 101.36 105.99 142.51 153.26 138.91 101.86 144.8933333 2266 2333 2152 1443.47 2250.333333 1.74E-16 0.628699049 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation 66412 66412 'Arrdc4' mRNA 1105 1102 1111 25.53 26.27 27.22 30.05 29.82 34.16 26.34 31.34333333 1483 1411 1531 1106 1475 1.73E-06 0.402596064 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1903561///extracellular vesicle "GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0140112///extracellular vesicle biogenesis 66413 66413 'Psmd6' mRNA 1350 1409 1368 60.79 62.62 65.35 73.85 82.01 77.16 62.92 77.67333333 1883 2040 1903 1375.666667 1942 1.50E-09 0.486034297 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection GO:0000502///proteasome complex+++GO:0005838///proteasome regulatory particle+++GO:0022624///proteasome accessory complex GO:0030234///enzyme regulator activity GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity 66414 66414 'Ndufa12' mRNA 2363 2299 2417 146.15 140.59 158.61 135.21 165.56 143.26 148.45 148.01 2507 2992 2567 2359.666667 2688.666667 0.070878796 0.176322925 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0006979///response to oxidative stress+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0042775///mitochondrial ATP synthesis coupled electron transport 66416 66416 'Ndufa7' mRNA 2345 2200 2393 364.97 341.99 395.41 308.88 371.18 326.32 367.4566667 335.46 2259 2635 2297 2312.666667 2397 0.751368437 0.038955189 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005761///mitochondrial ribosome+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003735///structural constituent of ribosome+++GO:0008137///NADH dehydrogenase (ubiquinone) activity "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032543///mitochondrial translation+++GO:0042773///ATP synthesis coupled electron transport" 66419 66419 'Mrpl11' mRNA 585 650 602 11.16 12.2 12.18 11.17 12.89 12.05 11.84666667 12.03666667 675 761 705 612.3333333 713.6666667 0.080103683 0.210472334 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0070180///large ribosomal subunit rRNA binding GO:0006412///translation 66420 66420 'Polr2e' mRNA 1854 2000 1831 117.36 125.2 122.99 118.32 114.42 120.55 121.85 117.7633333 2143 2020 2110 1895 2091 0.086806832 0.13052893 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005666///RNA polymerase III complex+++GO:0005736///RNA polymerase I complex" GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 66421 66421 '2410004B18Rik' mRNA 340 356 323 12.86 13.29 12.94 13.22 14.45 13.77 13.03 13.81333333 402 429 405 339.6666667 412 0.057375589 0.268430683 GO:0005654///nucleoplasm GO:0008150///biological_process 66422 66422 'Dctpp1' mRNA 170 154 174 19.98 18 21.7 25.22 35.04 31.18 19.89333333 30.48 245 331 292 166 289.3333333 2.94E-05 0.790216805 00240///Pyrimidine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0016462///pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0032556///pyrimidine deoxyribonucleotide binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0047840///dCTP diphosphatase activity GO:0006253///dCTP catabolic process+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0042262///DNA protection 66423 66423 'Coprs' mRNA 608 556 578 51.62 46.3 51.43 40.48 45.09 40.44 49.78333333 42.00333333 541 594 526 580.6666667 553.6666667 0.593899688 -0.08049811 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0042393///histone binding GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0007517///muscle organ development+++GO:0043985///histone H4-R3 methylation 66425 66425 'Pcp4l1' mRNA 787 755 852 29.32 27.73 33.67 40.43 39.34 37.26 30.24 39.01 1247 1184 1112 798 1181 6.66E-08 0.550155941 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66427 66427 'Cyb5b' mRNA 3449 3623 3828 43.2 44.63 50.86 43.58 41.72 38 46.23 41.1 4005 3745 3382 3633.333333 3710.666667 0.888377162 0.014931765 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:1903958///nitric-oxide synthase complex GO:0008047///enzyme activator activity+++GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050421///nitrite reductase (NO-forming) activity GO:0006809///nitric oxide biosynthetic process+++GO:0022900///electron transport chain+++GO:0050790///regulation of catalytic activity 66431 66431 'Oxld1' mRNA 161 159 149 13.33 13.07 13.13 10.71 9.27 11.02 13.17666667 10.33333333 148 125 147 156.3333333 140 0.488627705 -0.17111521 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 66432 66432 'Slc7a6os' mRNA 297 257 203 11.48 9.8 8.32 12.62 12.34 13.32 9.866666667 12.76 375 358 383 252.3333333 372 5.05E-04 0.553114415 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation+++GO:0015031///protein transport+++GO:0032502///developmental process 66433 66433 'Chchd7' mRNA 881 846 821 87.11 83.07 87.6 78.07 74 75.48 85.92666667 75.85 836 798 804 849.3333333 812.6666667 0.514624894 -0.07540962 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0003674///molecular_function GO:0008150///biological_process 66435 66435 'Uggt2' mRNA 295 354 298 2.56 2.96 2.73 2.24 2.52 2.56 2.75 2.44 305 323 316 315.6666667 314.6666667 0.944249165 -0.014077779 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0032991///protein-containing complex GO:0003980///UDP-glucose:glycoprotein glucosyltransferase activity+++GO:0016740///transferase activity+++GO:0051082///unfolded protein binding GO:0006486///protein glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0097359///UDP-glucosylation 66437 66437 'Fis1' mRNA 3812 3712 3621 328.01 316.68 329.54 335.32 335.4 337.06 324.7433333 335.9266667 4453 4355 4324 3715 4377.333333 1.70E-04 0.224813643 04137///Mitophagy - animal GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0032991///protein-containing complex GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0000266///mitochondrial fission+++GO:0000422///autophagy of mitochondrion+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006626///protein targeting to mitochondrion+++GO:0006915///apoptotic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008053///mitochondrial fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0016559///peroxisome fission+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0070584///mitochondrion morphogenesis+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1901653///cellular response to peptide+++GO:1903579///negative regulation of ATP metabolic process+++GO:1904579///cellular response to thapsigargin+++GO:2000192///negative regulation of fatty acid transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 66438 66438 'Hamp2' mRNA 2 0 0 0.43 0 0 0.38 0 0.2 0.143333333 0.193333333 2 0 1 0.666666667 1 0.876795627 0.578298478 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0014704///intercalated disc+++GO:0045179///apical cortex GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0097690///iron channel inhibitor activity GO:0002092///positive regulation of receptor internalization+++GO:0006879///cellular iron ion homeostasis+++GO:0007165///signal transduction+++GO:0010039///response to iron ion+++GO:0031640///killing of cells of other organism+++GO:0032413///negative regulation of ion transmembrane transporter activity+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0042742///defense response to bacterium+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1902916///positive regulation of protein polyubiquitination+++GO:1904039///negative regulation of ferrous iron export+++GO:1904255///negative regulation of iron channel activity+++GO:1904479///negative regulation of intestinal absorption+++GO:2000646///positive regulation of receptor catabolic process 66439 66439 'Borcs7' mRNA 687 731 695 17.82 18.67 19.12 11.41 13.44 11.88 18.53666667 12.24333333 506 582 510 704.3333333 532.6666667 3.99E-04 -0.413750422 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0099078///BORC complex GO:0003674///molecular_function GO:0008150///biological_process 66440 66440 'Cdc26' mRNA 848.3 823.62 756.69 15.32 14.64 14.51 16.86 17.86 15.79 14.82333333 16.83666667 1074.51 1111.16 973.82 809.5366667 1053.163333 1.38E-04 0.369660299 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 66441 66441 'Magohb' mRNA 121 98 89 10.66 8.18 8.24 12.53 14.45 13.39 9.026666667 13.45666667 161 181 169 102.6666667 170.3333333 0.001271417 0.722505839 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0043025///neuronal cell body+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0007292///female gamete generation+++GO:0008380///RNA splicing+++GO:0051028///mRNA transport" 66442 66442 'Spc25' mRNA 9 16 12 0.37 0.72 0.51 11.07 11.64 10.77 0.533333333 11.16 300 305 284 12.33333333 296.3333333 3.96E-52 4.576370568 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0031262///Ndc80 complex" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007059///chromosome segregation+++GO:0051301///cell division 66443 66443 'Tnfaip8l1' mRNA 778.25 760.4 630.16 13.26 12.43 11.86 6.25 6.48 6.22 12.51666667 6.316666667 406.08 412.1 428.56 722.9366667 415.58 9.33E-13 -0.80699134 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0032007///negative regulation of TOR signaling+++GO:0042981///regulation of apoptotic process 66445 66445 'Cyc1' mRNA 4265 4516 4227 193.51 203.52 202.64 213.59 210.09 208.72 199.89 210.8 5424 5237 5119 4336 5260 3.98E-06 0.26690011 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0005515///protein binding+++GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0022900///electron transport chain+++GO:0033762///response to glucagon+++GO:1902600///proton transmembrane transport" 66446 66446 'Exosc7' mRNA 757.09 627.68 683.25 41.43 33.96 39.3 35.38 43.03 39.21 38.23 39.20666667 745.25 834.15 763.91 689.34 781.1033333 0.192659799 0.168486267 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0016075///rRNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034473///U1 snRNA 3'-end processing+++GO:0034475///U4 snRNA 3'-end processing+++GO:0034476///U5 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0071028///nuclear mRNA surveillance+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process" 66447 66447 'Mgst3' mRNA 2008 1931 1816 114.54 108.85 109.91 50.52 53.25 55.04 111.1 52.93666667 1016 1044 1070 1918.333333 1043.333333 3.57E-31 -0.889072029 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004364///glutathione transferase activity+++GO:0004464///leukotriene-C4 synthase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006629///lipid metabolic process+++GO:0010243///response to organonitrogen compound+++GO:0019370///leukotriene biosynthetic process+++GO:0098869///cellular oxidant detoxification 66448 66448 'Mrpl20' mRNA 923 957 946 60.52 62.07 65.82 82.65 82.57 82.34 62.80333333 82.52 1450 1412 1392 942 1418 4.52E-12 0.577487855 03010///Ribosome GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation 66449 66449 'Pam16' mRNA 627 584 679 90.71 84.29 104.29 69.72 83.95 79.52 93.09666667 77.73 549 642 603 630 598 0.581292202 -0.089151822 "GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0032991///protein-containing complex" GO:0005515///protein binding GO:0001503///ossification+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0032780///negative regulation of ATPase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0071897///DNA biosynthetic process+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:1902511///negative regulation of apoptotic DNA fragmentation+++GO:2001234///negative regulation of apoptotic signaling pathway 66451 66451 '2610528J11Rik' mRNA 385 343 299 27.53 24.19 22.6 14.48 17.64 16.95 24.77333333 16.35666667 232 276 263 342.3333333 257 0.010209884 -0.420728073 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0003674///molecular_function 66454 66454 'Nmnat1' mRNA 365.25 420.89 369.36 9.06 10.31 9.8 9.12 8.54 9.37 9.723333333 9.01 418.8 384.7 415.23 385.1666667 406.2433333 0.710661729 0.065520208 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0000309///nicotinamide-nucleotide adenylyltransferase activity+++GO:0003824///catalytic activity+++GO:0004515///nicotinate-nucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042802///identical protein binding GO:0009058///biosynthetic process+++GO:0009435///NAD biosynthetic process+++GO:0009611///response to wounding+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0043524///negative regulation of neuron apoptotic process+++GO:1901215///negative regulation of neuron death+++GO:1902511///negative regulation of apoptotic DNA fragmentation+++GO:1990966///ATP generation from poly-ADP-D-ribose 66455 66455 'Cnpy4' mRNA 713 773 794 23.1 24.69 27.29 35.13 34.98 34.93 25.02666667 35.01333333 1246 1211 1199 760 1218.666667 2.00E-12 0.667442187 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0005102///signaling receptor binding GO:0032880///regulation of protein localization+++GO:1903078///positive regulation of protein localization to plasma membrane 66459 66459 'Pyurf' mRNA 967 985 1035 9.52 9.53 10.81 10.24 9.54 9.1 9.953333333 9.626666667 1197 1090 1031 995.6666667 1106 0.211697957 0.136880679 GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0006506///GPI anchor biosynthetic process+++GO:0009893///positive regulation of metabolic process 66460 66460 'Sys1' mRNA 2199 2141 1967 78.16 75.24 74.31 64.47 67.04 68.45 75.90333333 66.65333333 2074 2104 2137 2102.333333 2105 0.930263498 -0.008247424 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0003674///molecular_function GO:0006895///Golgi to endosome transport+++GO:0015031///protein transport+++GO:0034067///protein localization to Golgi apparatus+++GO:0043001///Golgi to plasma membrane protein transport 664609 664609 'Rhox4a' mRNA 1.67 0 0 0.08 0 0 0 0.56 0 0.026666667 0.186666667 0 6.05 0 0.556666667 2.016666667 0.464397195 2.492994198 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003677///DNA binding GO:0008150///biological_process 66461 66461 'Ptpmt1' mRNA 626 603 510 28.56 27.16 24.69 23.81 22 22.64 26.80333333 22.81666667 599 540 551 579.6666667 563.3333333 0.744583869 -0.050663754 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane "GO:0004439///phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008962///phosphatidylglycerophosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity" GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016311///dephosphorylation+++GO:0032049///cardiolipin biosynthetic process+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:2001242///regulation of intrinsic apoptotic signaling pathway 664610 664610 'Rhox4d' mRNA 2.26 0 0 0.21 0 0 0 0 0.08 0.07 0.026666667 0 0 1.02 0.753333333 0.34 0.863090843 -0.883164662 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0008150///biological_process 66462 66462 'Rex1bd' mRNA 985 885 839 106.93 95.41 96.61 102.54 103.88 98.74 99.65 101.72 1076 1062 998 903 1045.333333 0.043862195 0.200614073 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66464 66464 'Taf12' mRNA 418 495 423 19.02 22.19 20.51 32.44 32.53 32.28 20.57333333 32.41666667 835 811 783 445.3333333 809.6666667 3.10E-15 0.851911823 03022///Basal transcription factors GO:0000124///SAGA complex+++GO:0000125///PCAF complex+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0030914///STAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0046695///SLIK (SAGA-like) complex GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0046982///protein heterodimerization activity "GO:0006352///DNA-templated transcription, initiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051123///RNA polymerase II preinitiation complex assembly" 66467 66467 'Gtf2h5' mRNA 958 1022 903 49.24 51.74 49.1 57.49 63.12 59.69 50.02666667 60.1 1275 1358 1273 961 1302 8.49E-07 0.428474623 03022///Basal transcription factors+++03420///Nucleotide excision repair GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0005515///protein binding "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006362///transcription elongation from RNA polymerase I promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016032///viral process+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0071480///cellular response to gamma radiation" 66468 66468 'Ska1' mRNA 1 2 3 0.02 0.04 0.07 1.36 1.27 1.35 0.043333333 1.326666667 75 68 72 2 71.66666667 3.35E-13 5.149016385 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0072686///mitotic spindle" GO:0008017///microtubule binding GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0051301///cell division 66469 66469 'Prxl2b' mRNA 544 560 506 47.5 48.48 46.89 54.41 60.89 63 47.62333333 59.43333333 713 777 797 536.6666667 762.3333333 5.13E-06 0.496899726 00590///Arachidonic acid metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043209///myelin sheath "GO:0008379///thioredoxin peroxidase activity+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0047017///prostaglandin-F synthase activity" GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0098869///cellular oxidant detoxification 66471 66471 'Anp32e' mRNA 3116 3213 2570 54.89 58.92 49.81 46.19 51.22 51.9 54.54 49.77 2772 2736 2761 2966.333333 2756.333333 0.150200064 -0.113517351 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0019212///phosphatase inhibitor activity+++GO:0042393///histone binding GO:0006325///chromatin organization+++GO:0042981///regulation of apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0043486///histone exchange 66473 66473 'Ctrb1' mRNA 0 0 1 0 0 0.08 0 0 0.07 0.026666667 0.023333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005764///lysosome GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007586///digestion+++GO:0030163///protein catabolic process+++GO:0034097///response to cytokine+++GO:0043065///positive regulation of apoptotic process 66475 66475 'Rps23' mRNA 3245.03 3105.39 3068.28 465.54 444.39 467.29 569.22 599.77 614.18 459.0733333 594.39 4520.62 4626.06 4697.17 3139.566667 4614.616667 2.12E-18 0.544171505 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0034063///stress granule assembly+++GO:1990145///maintenance of translational fidelity 66477 66477 'Atp5md' mRNA 1406.99 1350.98 1694.99 431.49 419.79 553.25 408.25 433.96 458.16 468.1766667 433.4566667 1496.97 1537.95 1609.98 1484.32 1548.3 0.775462196 0.043358933 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process 66479 66479 '1700029F12Rik' mRNA 0 1 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 664799 664799 'Ctcfl' mRNA 24.96 24.14 35.31 0.42 0.4 0.63 0.26 0.34 0.3 0.483333333 0.3 17.47 22.78 20.05 28.13666667 20.1 0.39504719 -0.511153638 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0043035///chromatin insulator sequence binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0016571///histone methylation+++GO:0043046///DNA methylation involved in gamete generation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051569///regulation of histone H3-K4 methylation" 66480 66480 'Rpl15' mRNA 4352.96 4396.95 4250.15 134.91 134.18 139.56 199.72 205.19 203.76 136.2166667 202.89 7426.97 7454.47 7350.87 4333.353333 7410.77 1.06E-44 0.76249224 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0031672///A band GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0045471///response to ethanol 664804 664804 'Gm7347' mRNA 66.3 55.33 62.39 0.97 0.8 0.99 0.07 0.04 0.03 0.92 0.046666667 4.83 3.19 2.05 61.34 3.356666667 5.04E-12 -4.36064778 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 664805 664805 'Skor2' mRNA 565 558 480 7.34 7.13 6.62 0.72 0.64 0.66 7.03 0.673333333 64 55 57 534.3333333 58.66666667 5.58E-78 -3.196894768 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0042826///histone deacetylase binding+++GO:0046332///SMAD binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021587///cerebellum morphogenesis+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021936///regulation of cerebellar granule cell precursor proliferation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048468///cell development+++GO:0048814///regulation of dendrite morphogenesis 66481 66481 'Rps21' mRNA 452 471 592 117.12 123.02 163.63 121.18 107.32 133.08 134.59 120.5266667 526 452 556 505 511.3333333 0.998591786 -0.001417292 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome+++GO:0043022///ribosome binding+++GO:0047485///protein N-terminus binding "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002181///cytoplasmic translation+++GO:0006412///translation" 66482 66482 'Exoc2' mRNA 941 906 971 11.99 11.35 13.11 11.23 10.96 9.99 12.15 10.72666667 1009 966 875 939.3333333 950 0.995389082 0.001999997 04014///Ras signaling pathway+++05132///Salmonella infection GO:0000145///exocyst+++GO:0005886///plasma membrane+++GO:0090543///Flemming body GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0047485///protein N-terminus binding GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0045921///positive regulation of exocytosis+++GO:2000535///regulation of entry of bacterium into host cell 66483 66483 'Rpl36al' mRNA 1491 1361 1510 239.31 218.3 257.31 438.14 486.79 485.21 238.3066667 470.0466667 3106 3349 3310 1454 3255 1.37E-44 1.149381176 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0010033///response to organic substance+++GO:0032526///response to retinoic acid 664837 664837 'Gm7361' mRNA 21.61 23.61 20.39 0.33 0.36 0.36 0.08 0.03 0.1 0.35 0.07 5 2 5.96 21.87 4.32 0.00175257 -2.428351549 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66487 66487 'Smim4' mRNA 285 325 419 51.25 54.23 86.89 57.21 58.67 65.47 64.12333333 60.45 299 286 321 343 302 0.327351797 -0.203662315 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66488 66488 'Fam136a' mRNA 727.92 748.9 761.94 25.98 26.21 28.69 24.08 25.2 26.66 26.96 25.31333333 776 795.99 834.98 746.2533333 802.3233333 0.458221257 0.092514101 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 664883 664883 'Nova1' mRNA 79 72 74 1.16 1.01 1.13 0.83 0.63 0.84 1.1 0.766666667 63 48 63 75 58 0.262810857 -0.384606198 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:1990825///sequence-specific mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010468///regulation of gene expression+++GO:0050684///regulation of mRNA processing+++GO:0051252///regulation of RNA metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis" 66489 66489 'Rpl35' mRNA 2815 2879 3250 566.76 581.75 694.98 693.96 835.17 794.56 614.4966667 774.5633333 3909 4558 4300 2981.333333 4255.666667 9.09E-08 0.498982381 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0043021///ribonucleoprotein complex binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006412///translation" 66491 66491 'Polr2l' mRNA 1016.48 1050.86 1262.78 35.4 36.08 46.65 40.61 47.86 44.22 39.37666667 44.23 1340.1 1541.39 1412.1 1110.04 1431.196667 0.003472805 0.351155324 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005666///RNA polymerase III complex+++GO:0005736///RNA polymerase I complex" GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006360///transcription by RNA polymerase I+++GO:0006366///transcription by RNA polymerase II+++GO:0042797///tRNA transcription by RNA polymerase III" 66492 66492 'Zmat2' mRNA 2172 1978 2184 54.12 48.53 57.72 60.36 58.63 57.88 53.45666667 58.95666667 2786 2642 2586 2111.333333 2671.333333 5.57E-05 0.324786487 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 66493 66493 'Mrpl51' mRNA 1466.01 1578 1565.85 57.09 60.61 64.7 70.6 81.51 76.31 60.8 76.14 2082.43 2346.06 2177.49 1536.62 2201.993333 3.16E-09 0.50731602 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 66494 66494 'Prelid1' mRNA 3052 3072 2884 175.65 174.73 176.11 276.71 280.01 270.58 175.4966667 275.7666667 5515 5441 5213 3002.666667 5389.666667 1.78E-49 0.832727729 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex GO:1990050///phosphatidic acid transporter activity GO:0006869///lipid transport+++GO:0006915///apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0010950///positive regulation of endopeptidase activity+++GO:0015914///phospholipid transport+++GO:0043066///negative regulation of apoptotic process+++GO:0045580///regulation of T cell differentiation+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070234///positive regulation of T cell apoptotic process+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097035///regulation of membrane lipid distribution+++GO:0120009///intermembrane lipid transfer+++GO:1901857///positive regulation of cellular respiration+++GO:2001140///positive regulation of phospholipid transport 66495 66495 'Ndufb3' mRNA 1381 1305 1313 128.23 120.21 129.39 123.06 133.17 127.33 125.9433333 127.8533333 1516 1597 1514 1333 1542.333333 0.022325027 0.198814178 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0022900///electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly 66496 66496 'Ppdpf' mRNA 1820 1758 1775 142.74 138.09 150.11 145 154.09 150.23 143.6466667 149.7733333 2086 2157 2092 1784.333333 2111.666667 0.002764123 0.230948879 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0030154///cell differentiation 664968 664968 'Tmem238' mRNA 555 532 311 33.36 31.61 19.84 13.89 18.07 17.08 28.27 16.34666667 265 336 315 466 305.3333333 0.001349793 -0.608162452 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 664969 664969 'Gm7429' mRNA 41.15 33.01 28.16 8 6.44 5.82 8.2 7.33 8.78 6.753333333 8.103333333 47.82 41.43 49.2 34.10666667 46.15 0.356894114 0.417172628 66497 66497 'Cmss1' mRNA 177 179 177 9.33 9.32 9.94 6.8 5.98 6.03 9.53 6.27 148 127 127 177.6666667 134 0.046054233 -0.42036105 GO:0008150///biological_process 66498 66498 'Dda1' mRNA 1885 1941 1753 55.63 56.44 54.88 59.2 61.86 61.41 55.65 60.82333333 2305 2350 2315 1859.666667 2323.333333 5.96E-06 0.310995104 GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 664987 664987 'Gm14393' mRNA 531.3 495.48 516.75 3.2 2.95 3.3 1.76 1.85 1.94 3.15 1.85 338.18 347.2 356.96 514.51 347.4466667 5.72E-06 -0.579249996 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 664994 664994 'Isoc2a' mRNA 30 34 18 1.73 1.94 1.1 0.75 0.77 0.94 1.59 0.82 15 15 18 27.33333333 16 0.194617196 -0.773184786 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0031648///protein destabilization 66500 66500 'Slc30a7' mRNA 614.03 625.19 535 3.76 5.7 4.12 9.55 9.56 10.91 4.526666667 10.00666667 985.01 931.01 990.11 591.4066667 968.71 1.78E-13 0.702400144 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005385///zinc ion transmembrane transporter activity+++GO:0008270///zinc ion binding+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006829///zinc ion transport+++GO:0032119///sequestering of zinc ion+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport 665001 665001 'Gm14391' mRNA 530.87 531.05 500.91 8.23 8.96 9.61 3.94 3.8 4.46 8.933333333 4.066666667 303.42 262.01 376.71 520.9433333 314.0466667 3.89E-07 -0.741734061 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 66501 66501 '1700029H14Rik' mRNA 1 0 3 0.04 0 0.13 0 0.08 0 0.056666667 0.026666667 0 2 0 1.333333333 0.666666667 0.776712627 -1.037483081 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 665033 665033 'Col6a5' mRNA 0 0 1 0 0 0.01 0.11 0.05 0.01 0.003333333 0.056666667 22 10.95 1.02 0.333333333 11.32333333 0.004751705 4.915592291 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization 66505 66505 'Zmynd11' mRNA 1622 1688 1434 21.61 21.98 20.21 16.71 15.82 17.36 21.26666667 16.63 1446 1351 1457 1581.333333 1418 0.043999521 -0.166827979 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046329///negative regulation of JNK cascade+++GO:0051607///defense response to virus+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 66506 66506 'Psmg3' mRNA 349 377 287 26.78 28.77 23.63 33.55 38.4 32.56 26.39333333 34.83666667 495 553 462 337.6666667 503.3333333 4.50E-05 0.569380053 GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity GO:0043248///proteasome assembly+++GO:0051131///chaperone-mediated protein complex assembly 66508 66508 'Lamtor1' mRNA 1835 1950 1860 95.25 99.97 102.43 155.28 174.16 167.75 99.21666667 165.73 3433 3755 3586 1881.666667 3591.333333 7.25E-38 0.921550855 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0045121///membrane raft+++GO:0071986///Ragulator complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0060090///molecular adaptor activity GO:0001558///regulation of cell growth+++GO:0001919///regulation of receptor recycling+++GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0010872///regulation of cholesterol esterification+++GO:0010874///regulation of cholesterol efflux+++GO:0016197///endosomal transport+++GO:0032008///positive regulation of TOR signaling+++GO:0032418///lysosome localization+++GO:0034613///cellular protein localization+++GO:0042632///cholesterol homeostasis+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity+++GO:0060620///regulation of cholesterol import+++GO:0071230///cellular response to amino acid stimulus 665095 665095 'Cyp2j8' mRNA 11 5 9 0.3 0.14 0.26 0.07 0.05 0.07 0.233333333 0.063333333 3 2 3 8.333333333 2.666666667 0.160441803 -1.662912963 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 66510 66510 'Rnf181' mRNA 4270 4174 4021 177.48 171.07 177.4 186.2 187.5 187.81 175.3166667 187.17 5143 5056 5020 4155 5073 1.09E-06 0.276428487 GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination 66511 66511 'Chtop' mRNA 3335 3382 3380 63.14 62.57 68.81 53.02 52.56 54.03 64.84 53.20333333 3075 2981 3044 3365.666667 3033.333333 0.017500374 -0.162856319 GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008327///methyl-CpG binding GO:0001701///in utero embryonic development+++GO:0006406///mRNA export from nucleus+++GO:0008284///positive regulation of cell proliferation+++GO:0031062///positive regulation of histone methylation+++GO:0032781///positive regulation of ATPase activity+++GO:0051096///positive regulation of helicase activity 665113 665113 'Tnik' mRNA 549 591 511 3.74 3.93 3.65 1.97 1.44 1.63 3.773333333 1.68 332 254 295 550.3333333 293.6666667 2.95E-12 -0.917846499 04013///MAPK signaling pathway - fly "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016324///apical plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000165///MAPK cascade+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007010///cytoskeleton organization+++GO:0007256///activation of JNKK activity+++GO:0007399///nervous system development+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0030033///microvillus assembly+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031532///actin cytoskeleton reorganization+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0046777///protein autophosphorylation+++GO:0048812///neuron projection morphogenesis+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane 665119 665119 'Sec14l5' mRNA 1045 1126 1133 11.44 11.4 12.25 4.3 4.47 4.51 11.69666667 4.426666667 499 538 518 1101.333333 518.3333333 7.35E-27 -1.099995686 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66513 66513 'Tab1' mRNA 1087 1314 1268 20.2 24.08 25.07 14.58 13.41 13.64 23.11666667 13.87666667 901 807 816 1223 841.3333333 8.20E-08 -0.553948382 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05161///Hepatitis B+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016791///phosphatase activity+++GO:0019209///kinase activator activity+++GO:0044877///protein-containing complex binding+++GO:0048273///mitogen-activated protein kinase p38 binding GO:0000185///activation of MAPKKK activity+++GO:0001701///in utero embryonic development+++GO:0003007///heart morphogenesis+++GO:0003279///cardiac septum development+++GO:0006469///negative regulation of protein kinase activity+++GO:0006470///protein dephosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016311///dephosphorylation+++GO:0030324///lung development+++GO:0035904///aorta development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0060976///coronary vasculature development 66514 66514 'Asrgl1' mRNA 1026 1081 1117 25.35 26.31 29.28 18.46 18.2 19.13 26.98 18.59666667 859 827 862 1074.666667 849.3333333 3.21E-04 -0.353364846 "00250///Alanine, aspartate and glutamate metabolism" GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm GO:0004067///asparaginase activity+++GO:0008233///peptidase activity+++GO:0008798///beta-aspartyl-peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0033345///asparagine catabolic process via L-aspartate 66515 66515 'Cul7' mRNA 473 503 464 4.55 4.76 4.74 4.72 3.44 3.84 4.683333333 4 565 402 445 480 470.6666667 0.82958916 -0.042477812 04120///Ubiquitin mediated proteolysis GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:1990393///3M complex GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0000226///microtubule cytoskeleton organization+++GO:0000281///mitotic cytokinesis+++GO:0001570///vasculogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0001890///placenta development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0007030///Golgi organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0042981///regulation of apoptotic process+++GO:0045601///regulation of endothelial cell differentiation+++GO:0050775///positive regulation of dendrite morphogenesis 665155 665155 'Srp54b' mRNA 1338.66 1230.4 1344.12 22.24 20.11 23.69 26.69 22.72 24.77 22.01333333 24.72666667 1848.9 1536.92 1661.13 1304.393333 1682.316667 1.70E-04 0.351455048 03060///Protein export "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0048500///signal recognition particle" GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008312///7S RNA binding+++GO:0019003///GDP binding+++GO:0030942///endoplasmic reticulum signal peptide binding+++GO:0043021///ribonucleoprotein complex binding "GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0030593///neutrophil chemotaxis+++GO:0030851///granulocyte differentiation+++GO:0031017///exocrine pancreas development+++GO:0045047///protein targeting to ER" 665180 665180 'Clec2l' mRNA 7 6 10 0.29 0.25 0.44 0.25 0.37 0.53 0.326666667 0.383333333 7 10 14 7.666666667 10.33333333 0.705271515 0.412748669 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030246///carbohydrate binding GO:0008150///biological_process 66520 66520 '2610001J05Rik' mRNA 1432 1446 1466 24.66 24.5 26.78 33.96 34.39 31.75 25.31333333 33.36666667 2269 2244 2054 1448 2189 8.58E-14 0.583144749 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66521 66521 'Rwdd1' mRNA 682.45 682.86 646.38 39.59 39.15 39.78 57.62 57.22 55.2 39.50666667 56.68 1139.36 1103.11 1055.01 670.5633333 1099.16 7.06E-15 0.702479469 GO:0005737///cytoplasm+++GO:0005844///polysome GO:0003674///molecular_function GO:0002181///cytoplasmic translation+++GO:0007569///cell aging+++GO:0030521///androgen receptor signaling pathway+++GO:0034599///cellular response to oxidative stress+++GO:0071394///cellular response to testosterone stimulus+++GO:2000825///positive regulation of androgen receptor activity 665211 665211 'Gm14326' mRNA 1811.18 1698.09 1673.55 14.58 13.87 14.19 9.96 10.2 10.17 14.21333333 10.11 1008.62 958.91 1014.05 1727.606667 993.86 1.04E-24 -0.810089462 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 66522 66522 'Pgpep1' mRNA 2337 2346 2216 25.54 25.22 25.73 31.11 31.97 31.8 25.49666667 31.62666667 3273 3286 3241 2299.666667 3266.666667 1.25E-15 0.495302266 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016920///pyroglutamyl-peptidase activity GO:0006508///proteolysis 66523 66523 '2810004N23Rik' mRNA 273 304 273 11.83 12.99 12.55 18.11 18.83 16.69 12.45666667 17.87666667 480 487 428 283.3333333 465 2.10E-07 0.703851902 GO:0005694///chromosome GO:0008150///biological_process 66525 66525 'Timm50' mRNA 996 1073 944 52.07 55.4 52.36 54.21 55.92 58.05 53.27666667 56.06 1190 1197 1232 1004.333333 1206.333333 0.003907222 0.254392313 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005134///interleukin-2 receptor binding+++GO:0043021///ribonucleoprotein complex binding GO:0001836///release of cytochrome c from mitochondria+++GO:0006470///protein dephosphorylation+++GO:0007006///mitochondrial membrane organization+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0035335///peptidyl-tyrosine dephosphorylation 665255 665255 'Vmn2r28' mRNA 0 4 2 0 0.08 0.04 0 0 0 0.04 0 0 0 0 2 0 0.294715032 -3.448918583 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 66526 66526 'Tceanc2' mRNA 369 361 377 3.13 3.01 3.39 3.18 3.44 3.2 3.176666667 3.273333333 431 456 422 369 436.3333333 0.110766889 0.229213587 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function "GO:0006351///transcription, DNA-templated" 665270 665270 'Plb1' mRNA 17 17 19 0.6 0.61 0.59 0.64 0.59 0.91 0.6 0.713333333 10 13 14 17.66666667 12.33333333 0.481243367 -0.530999456 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04977///Vitamin digestion and absorption GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane "GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0004623///phospholipase A2 activity+++GO:0004806///triglyceride lipase activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0050253///retinyl-palmitate esterase activity+++GO:0102545///phosphatidyl phospholipase B activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0019433///triglyceride catabolic process+++GO:0034478///phosphatidylglycerol catabolic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0042572///retinol metabolic process+++GO:0046338///phosphatidylethanolamine catabolic process+++GO:0046340///diacylglycerol catabolic process+++GO:2000344///positive regulation of acrosome reaction 66528 66528 'Smim5' mRNA 965 997.03 1004 44.33 49.08 51.07 7.5 6.98 6.5 48.16 6.993333333 186 173 169 988.6766667 176 2.69E-98 -2.503438706 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66530 66530 'Ubxn6' mRNA 1862.85 1853.39 1654.91 58.5 57.51 55.99 36.54 35.02 36.42 57.33333333 35.99333333 1334.82 1271.19 1292.34 1790.383333 1299.45 1.05E-10 -0.472514259 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex GO:0016236///macroautophagy+++GO:0032510///endosome to lysosome transport via multivesicular body sorting pathway+++GO:0036503///ERAD pathway 665301 665301 'Gm20773' mRNA 0 0 0.5 0 0 0.05 0 0.01 0.11 0.016666667 0.04 0 0.09 1.21 0.166666667 0.433333333 0.863090843 0.950016071 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0035064///methylated histone binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007276///gamete generation" 66531 66531 'Cmc2' mRNA 342 336 337 13.26 12.87 14.24 15.65 17.09 16.85 13.45666667 16.53 450 474 459 338.3333333 461 0.001024607 0.434636106 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 66532 66532 'Rep15' mRNA 26 40 19 1.7 2.59 1.32 1.14 1.46 1.71 1.87 1.436666667 20 25 29 28.33333333 24.66666667 0.767677467 -0.198359055 GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0001881///receptor recycling+++GO:0033572///transferrin transport 66536 66536 'Nipsnap3b' mRNA 626 749 716 23.75 28 28.78 42.32 47.13 42.92 26.84333333 44.12333333 1279 1393 1258 697 1310 1.90E-18 0.89831733 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 66537 66537 'Pomp' mRNA 1915 1822 1905 181.09 170.96 191.18 260.53 284.9 273.89 181.0766667 273.1066667 3151 3354 3197 1880.666667 3234 2.08E-25 0.769608483 03050///Proteasome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding GO:0043248///proteasome assembly 665378 665378 'Gm7609' mRNA 21.52 5.68 13.75 0.44 0.1 0.3 1.68 1.35 1.75 0.28 1.593333333 99.42 77.37 100.68 13.65 92.49 4.62E-11 2.807387158 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 66538 66538 'Rps19bp1' mRNA 408 377 397 33.09 30.3 34.17 37.12 38.33 42.11 32.52 39.18666667 524 527 574 394 541.6666667 4.48E-04 0.446780594 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0008150///biological_process 66540 66540 'Fam107b' mRNA 2628 2867 2810 46.39 49.8 52.52 14.29 12.47 13.31 49.57 13.35666667 944 802 849 2768.333333 865 3.75E-95 -1.69247896 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007605///sensory perception of sound 66541 66541 'Immp1l' mRNA 1166 1149 1004 78.98 77 72.16 60.45 61.13 63.42 76.04666667 61.66666667 1023 1008 1037 1106.333333 1022.666667 0.205487402 -0.122837029 03060///Protein export GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0042720///mitochondrial inner membrane peptidase complex GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0006627///protein processing involved in protein targeting to mitochondrion 665433 665433 'H2ac23' mRNA 64.47 39.47 76.03 9.33 5.7 11.68 62.67 82.97 82.18 8.903333333 75.94 493.47 634.47 623.15 59.99 583.6966667 2.81E-56 3.273132669 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0008285///negative regulation of cell proliferation+++GO:0031507///heterochromatin assembly 66548 66548 'Adamtsl5' mRNA 588 549 535 10.64 9.81 10.24 8.5 7.08 7.85 10.23 7.81 539 440 483 557.3333333 487.3333333 0.113637281 -0.206496906 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0008201///heparin binding+++GO:0050436///microfibril binding GO:0030198///extracellular matrix organization 66549 66549 'Aggf1' mRNA 1423 1418 662 23.89 23.42 11.79 10.17 18.1 16.68 19.7 14.98333333 697 1212 1107 1167.666667 1005.333333 0.719489813 -0.20534922 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0048471///perinuclear region of cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II 66552 66552 'Sppl2a' mRNA 1890.06 1842.6 1717.77 22.14 20.86 21.33 36.55 34.13 36.04 21.44333333 35.57333333 3516.9 3301.55 3388.53 1816.81 3402.326667 1.70E-47 0.894069344 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane "GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0042803///protein homodimerization activity" GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0050776///regulation of immune response 665522 665522 'Rps12-ps15' mRNA 0 0 0.34 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.113333333 0 66556 66556 'Drap1' mRNA 490 413 370 31.29 26.06 25.07 31.29 38.19 34.3 27.47333333 34.59333333 561 668 595 424.3333333 608 1.61E-04 0.51173533 GO:0005634///nucleus+++GO:0017054///negative cofactor 2 complex+++GO:0090575///RNA polymerase II transcription factor complex GO:0001046///core promoter sequence-specific DNA binding+++GO:0001091///RNA polymerase II basal transcription factor binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 665562 665562 'Rpl31-ps12' mRNA 45.04 38.18 34.1 8.06 6.84 6.48 1.31 1.76 0 7.126666667 1.023333333 8.29 10.85 0 39.10666667 6.38 4.54E-05 -2.70923475 03010///Ribosome+++05171///Coronavirus disease - COVID-19 665563 665563 'Mthfd2l' mRNA 161 138 76 3.73 3.2 1.97 0.87 0.96 1.39 2.966666667 1.073333333 47 44 69 125 53.33333333 1.54E-04 -1.227489539 00670///One carbon pool by folate+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane GO:0003824///catalytic activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0004487///methylenetetrahydrofolate dehydrogenase (NAD+) activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016787///hydrolase activity GO:0000105///histidine biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006730///one-carbon metabolic process+++GO:0008152///metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0009256///10-formyltetrahydrofolate metabolic process+++GO:0035999///tetrahydrofolate interconversion 66557 66557 'Bpifb2' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region GO:0008289///lipid binding GO:0008150///biological_process 665574 665574 'Gm7694' mRNA 551 588 586 7.78 8.16 8.77 2.85 2.99 2.68 8.236666667 2.84 232 238 212 575 227.3333333 1.44E-24 -1.35166161 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 665578 665578 'Gm7697' mRNA 112.32 100.1 122.03 1.17 1.08 1.28 0.24 0.18 0.15 1.176666667 0.19 26.56 22.5 20.69 111.4833333 23.25 1.52E-12 -2.313522159 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 665579 665579 'Rps12-ps13' mRNA 0 0 0.34 0 0 0.07 0 0 0 0.023333333 0 0 0 0 0.113333333 0 66559 66559 'Metap1d' mRNA 1262 1374 1281 33.24 37.04 36.48 13.24 12.74 13.64 35.58666667 13.20666667 587 542 552 1305.666667 560.3333333 2.47E-42 -1.232606285 GO:0005739///mitochondrion GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0070084///protein initiator methionine removal 665596 665596 'H2bc23' mRNA 8.77 5.88 78.41 0.24 0.15 12.86 1.97 9.2 17.44 4.416666667 9.536666667 48.67 78.89 116.94 31.02 81.5 0.359809381 1.34235557 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0097677///STAT family protein binding GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0008150///biological_process+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 665622 665622 'H2bc24' mRNA 72.75 71.21 19.25 12.77 11.82 0.55 19.88 9.15 1.74 8.38 10.25666667 154.99 69 39.36 54.40333333 87.78333333 0.198124232 0.693411692 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0097677///STAT family protein binding GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0008150///biological_process+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 66566 66566 'Ntpcr' mRNA 491 491 496 25.77 25.61 27.56 58.04 60.69 58.01 26.31333333 58.91333333 1286 1312 1248 492.6666667 1282 2.63E-48 1.367564831 00230///Purine metabolism+++00730///Thiamine metabolism GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017111///nucleoside-triphosphatase activity GO:0008150///biological_process 66567 66567 '2510022D24Rik' mRNA 144 121 105 5.82 4.82 4.5 3.16 3.06 3.12 5.046666667 3.113333333 90 85 85.97 123.3333333 86.99 0.045442833 -0.517577925 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66568 66568 'Rwdd3' mRNA 197 236 194 7.73 9.17 8.12 2.88 2.77 2.92 8.34 2.856666667 84 79 83 209 82 6.21E-11 -1.359654178 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033235///positive regulation of protein sumoylation+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway 66569 66569 'Gdpd1' mRNA 1366 1394 1340 30.66 30.83 31.9 17.78 19.04 18.62 31.13 18.48 910 953 924 1366.666667 929 1.58E-11 -0.568235493 00565///Ether lipid metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004622///lysophospholipase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0070291///N-acylethanolamine metabolic process 66570 66570 'Cenpm' mRNA 15 18.06 18 0.46 0.85 0.8 6.3 4.98 5.96 0.703333333 5.746666667 129 116 123 17.02 122.6666667 1.17E-17 2.838122183 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol" GO:0003674///molecular_function GO:0008150///biological_process 665700 665700 'Hmcn2' mRNA 5 3 2 0.02 0.01 0.01 0.04 0.03 0.06 0.013333333 0.043333333 13 10 20 3.333333333 14.33333333 0.025807129 2.099546602 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0031012///extracellular matrix+++GO:0032154///cleavage furrow+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0050896///response to stimulus 66573 66573 'Dzip1' mRNA 339.04 323.96 278.2 2.9 2.74 2.62 2.9 2.4 2.37 2.753333333 2.556666667 352.59 281.62 273.8 313.7333333 302.67 0.758810608 -0.064119584 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097539///ciliary transition fiber GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0033365///protein localization to organelle+++GO:0043393///regulation of protein binding+++GO:0044782///cilium organization+++GO:0045184///establishment of protein localization+++GO:0045724///positive regulation of cilium assembly+++GO:0051220///cytoplasmic sequestering of protein+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium 66576 66576 'Uqcrh' mRNA 3788 3667 3879 557.45 538.51 606.02 540.46 632.95 586.4 567.3266667 586.6033333 4183 4757 4370 3778 4436.666667 0.007624139 0.219354519 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0044877///protein-containing complex binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0009060///aerobic respiration" 665775 665775 'Bod1l' mRNA 1180 1307 1072 6.04 6.58 5.86 5.79 4.89 5.62 6.16 5.433333333 1287 1066 1207 1186.333333 1186.666667 0.937599015 -0.009882272 GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005813///centrosome+++GO:0005876///spindle microtubule GO:0003677///DNA binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0051721///protein phosphatase 2A binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0032515///negative regulation of phosphoprotein phosphatase activity 66578 66578 'Mis18a' mRNA 94 101 101 4.37 4.64 4.99 13.74 13.01 13.2 4.666666667 13.31666667 339 313 315 98.66666667 322.3333333 3.72E-22 1.694951153 "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol" GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0044030///regulation of DNA methylation+++GO:0051301///cell division 66580 66580 'Esf1' mRNA 626 610 639 10.04 9.62 10.88 9.58 9.27 9.48 10.18 9.443333333 687 650 658 625 665 0.576844312 0.075935974 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003723///RNA binding GO:0006364///rRNA processing 665828 665828 'Gm10654' mRNA 0 2 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66583 66583 'Exosc1' mRNA 439 443 410 15.89 15.8 15.73 16.1 17.25 15.83 15.80666667 16.39333333 512 535 489 430.6666667 512 0.063049516 0.23909647 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006364///rRNA processing+++GO:0006396///RNA processing 66585 66585 'Snrnp40' mRNA 752 832 780 27.69 30.21 30.47 30.57 31.86 29.55 29.45666667 30.66 954 970 892 788 938.6666667 0.01902695 0.240736118 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0006397///mRNA processing+++GO:0008380///RNA splicing 665858 665858 'Gm7827' mRNA 6.53 2.63 6.11 0.1 0.04 0.1 0 0.01 0.07 0.08 0.026666667 0 1 5 5.09 2 0.486607382 -1.239708503 66586 66586 'Crls1' mRNA 96 83 79 3.4 2.92 3.07 3.35 2.84 3.66 3.13 3.283333333 114 90 113 86 105.6666667 0.334896503 0.285394449 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0008444///CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity+++GO:0008808///cardiolipin synthase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0043337///CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity" GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0032049///cardiolipin biosynthetic process+++GO:0046474///glycerophospholipid biosynthetic process+++GO:0097068///response to thyroxine+++GO:1905711///response to phosphatidylethanolamine 66587 66587 'Fastk' mRNA 1474 1403 924 42.15 39.53 30.05 28.69 33.57 31.12 37.24333333 31.12666667 1076 1252 1154 1267 1160.666667 0.405539319 -0.127487905 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016607///nuclear speck+++GO:0035770///ribonucleoprotein granule GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033867///Fas-activated serine/threonine kinase activity GO:0000963///mitochondrial RNA processing+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0044528///regulation of mitochondrial mRNA stability 66588 66588 'Cmpk1' mRNA 922 862 754 28.12 25.9 24.39 53.41 51.53 58.26 26.13666667 54.4 2013 1896 2125 846 2011.333333 5.46E-50 1.240117463 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004127///cytidylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0009041///uridylate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019205///nucleobase-containing compound kinase activity+++GO:0033862///UMP kinase activity+++GO:0036430///CMP kinase activity+++GO:0036431///dCMP kinase activity+++GO:0050145///nucleoside monophosphate kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006225///UDP biosynthetic process+++GO:0006227///dUDP biosynthetic process+++GO:0006240///dCDP biosynthetic process+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0046705///CDP biosynthetic process+++GO:0046940///nucleoside monophosphate phosphorylation 66589 66589 'Ube2v1' mRNA 4957 5247 5063 145.64 151.88 158.41 146.5 160.4 145.38 151.9766667 150.76 5730 6124 5492 5089 5782 0.015226181 0.172489361 04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0032991///protein-containing complex+++GO:0035370///UBC13-UEV1A complex GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006301///postreplication repair+++GO:0042275///error-free postreplication DNA repair+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070534///protein K63-linked ubiquitination 66590 66590 'Farsa' mRNA 1239 1160 1161 38.97 35.95 38.74 42.52 39.69 39.22 37.88666667 40.47666667 1554 1416 1387 1186.666667 1452.333333 0.001157073 0.278685454 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009328///phenylalanine-tRNA ligase complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004826///phenylalanine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0051290///protein heterotetramerization 66591 66591 'Mad2l1bp' mRNA 297 310 282 14.18 14.61 14.29 19.68 23.58 23.18 14.36 22.14666667 473 553 539 296.3333333 521.6666667 1.60E-09 0.806739869 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0031965///nuclear membrane GO:0005515///protein binding GO:0007094///mitotic spindle assembly checkpoint+++GO:0007096///regulation of exit from mitosis+++GO:1902426///deactivation of mitotic spindle assembly checkpoint 66592 66592 'Stoml2' mRNA 976 1134 1036 36.81 42.18 41.38 48.48 48.02 45.76 40.12333333 47.42 1471 1425 1346 1048.666667 1414 2.74E-06 0.419304397 GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0042101///T cell receptor complex+++GO:0045121///membrane raft GO:0008289///lipid binding+++GO:0051020///GTPase binding+++GO:1901612///cardiolipin binding "GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0010876///lipid localization+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0032743///positive regulation of interleukin-2 production+++GO:0034982///mitochondrial protein processing+++GO:0035710///CD4-positive, alpha-beta T cell activation+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0050852///T cell receptor signaling pathway+++GO:0051259///protein complex oligomerization+++GO:0051646///mitochondrion localization+++GO:0090297///positive regulation of mitochondrial DNA replication+++GO:1900210///positive regulation of cardiolipin metabolic process+++GO:1990046///stress-induced mitochondrial fusion" 66593 66593 'Diablo' mRNA 2124.8 2326.32 2242.04 62.52 67.36 69.9 48.67 47.54 49.33 66.59333333 48.51333333 1903.72 1818.42 1867.61 2231.053333 1863.25 3.28E-04 -0.272855366 04210///Apoptosis+++04215///Apoptosis - multiple species GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0035631///CD40 receptor complex GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0043065///positive regulation of apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0097193///intrinsic apoptotic signaling pathway 66594 66594 'Uqcr11' mRNA 4032 3856 4755 865.81 832.14 1084.67 635.17 749.25 710.77 927.54 698.3966667 3351 3828 3601 4214.333333 3593.333333 0.019982192 -0.246505332 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0009055///electron transfer activity "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c" 66595 66595 'Aste1' mRNA 337.77 284.64 260.8 6 4.91 4.79 4.09 3.46 3.8 5.233333333 3.783333333 258 223.91 239.85 294.4033333 240.5866667 0.082916478 -0.301400965 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66596 66596 'Gtf3a' mRNA 559.69 574.64 530.89 26.09 26.45 26.26 26.21 28.09 29.62 26.26666667 27.97333333 645.47 674.78 705.45 555.0733333 675.2333333 0.01617528 0.273131526 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008097///5S rRNA binding+++GO:0046872///metal ion binding GO:0006383///transcription by RNA polymerase III+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis 66597 66597 'Trim13' mRNA 288.49 308.78 293.56 8.47 9.04 10.35 7.74 7.67 7.95 9.286666667 7.786666667 283.77 270.06 297.52 296.9433333 283.7833333 0.700563941 -0.076639638 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0097038///perinuclear endoplasmic reticulum GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0002376///immune system process+++GO:0010332///response to gamma radiation+++GO:0010942///positive regulation of cell death+++GO:0016239///positive regulation of macroautophagy+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032897///negative regulation of viral transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:1902187///negative regulation of viral release from host cell" 66599 66599 'Rdm1' mRNA 1264 1278 1132 69.72 70.4 67.3 38.65 42.54 41.63 69.14 40.94 807 862 837 1224.666667 835.3333333 1.71E-10 -0.561214549 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016605///PML body GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding GO:0008150///biological_process 665992 665992 'Krtap4-8' mRNA 0 1 0 0 0.12 0 0 0 0 0.04 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 66601 66601 'Tmigd1' mRNA 72 68 65 2.78 2.66 2.73 4.02 4.73 4.97 2.723333333 4.573333333 119 137 144 68.33333333 133.3333333 1.57E-04 0.954907251 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection GO:0003674///molecular_function GO:0030334///regulation of cell migration+++GO:0042127///regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0090559///regulation of membrane permeability 66603 66603 'Gemin2' mRNA 240.79 213.14 229.45 8.87 7.74 8.97 8.56 8.23 8.06 8.526666667 8.283333333 266.76 250.29 243.2 227.7933333 253.4166667 0.48032198 0.140961833 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0097504///Gemini of coiled bodies GO:0000245///spliceosomal complex assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:1905215///negative regulation of RNA binding 666048 666048 'Trabd2b' mRNA 232 250 130 1.85 1.96 1.11 0.67 0.6 0.65 1.64 0.64 95 84 88 204 89 1.30E-06 -1.196964447 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031301///integral component of organelle membrane GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0017147///Wnt-protein binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031334///positive regulation of protein complex assembly+++GO:1904808///positive regulation of protein oxidation 66605 66605 '1700017N19Rik' mRNA 21 16 12 0.72 0.54 0.44 0 0.03 0 0.566666667 0.01 0 1 0 16.33333333 0.333333333 2.11E-04 -5.514810014 GO:0003729///mRNA binding+++GO:0046872///metal ion binding GO:0016973///poly(A)+ mRNA export from nucleus 66606 66606 'Lrrc57' mRNA 564 598 612 16.95 17.55 19.52 17.05 16.66 16.7 18.00666667 16.80333333 645 615 614 591.3333333 624.6666667 0.654104964 0.065414068 GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 666060 666060 'Frmpd1' mRNA 193 253 244 2.02 2.61 2.66 0.35 0.2 0.17 2.43 0.24 37 22 19 230 26 6.66E-30 -3.162265998 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0090150///establishment of protein localization to membrane 66607 66607 'Ms4a4d' mRNA 7 4 0 0.27 0.15 0 1.25 1.04 0.94 0.14 1.076666667 37 30 27 3.666666667 31.33333333 3.58E-05 3.097501494 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0003674///molecular_function GO:0008150///biological_process 66609 66609 'Cryzl1' mRNA 1244 1305 1238 40.04 41.4 42.29 29.32 29.32 27.96 41.24333333 28.86666667 1047 1022 966 1262.333333 1011.666667 1.25E-04 -0.331277791 GO:0016491///oxidoreductase activity 66610 66610 'Abi3' mRNA 119.12 126.36 126.19 1.55 1.67 2.15 14.15 14.04 14.74 1.79 14.31 757.63 731.72 761.85 123.89 750.4 1.01E-83 2.587697949 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0030027///lamellipodium+++GO:0031209///SCAR complex+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0002357///defense response to tumor cell+++GO:0010593///negative regulation of lamellipodium assembly+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030334///regulation of cell migration+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0099151///regulation of postsynaptic density assembly+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000774///positive regulation of cellular senescence 666105 666105 'Gm7932' mRNA 40.69 45 25 1.05 1.14 0.68 1.89 1.69 2.09 0.956666667 1.89 84.47 74 90.61 36.89666667 83.02666667 5.95E-04 1.169027242 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66611 66611 'Ribc1' mRNA 62 89 45 2.38 3.42 1.85 1.34 1.53 1.97 2.55 1.613333333 40 44 57 65.33333333 47 0.242631355 -0.47471929 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66612 66612 'Ormdl3' mRNA 4827 5026 4395 135.68 139.17 131.05 74.84 73 73.83 135.3 73.89 3061 2915 2923 4749.333333 2966.333333 1.41E-34 -0.689152359 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035339///SPOTS complex GO:0003674///molecular_function GO:0002903///negative regulation of B cell apoptotic process+++GO:0006672///ceramide metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0006940///regulation of smooth muscle contraction+++GO:0010508///positive regulation of autophagy+++GO:0042552///myelination+++GO:0061744///motor behavior+++GO:0090153///regulation of sphingolipid biosynthetic process+++GO:0090156///cellular sphingolipid homeostasis+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1904221///negative regulation of serine C-palmitoyltransferase activity+++GO:2000303///regulation of ceramide biosynthetic process 66614 66614 'Gpatch4' mRNA 151 142 126 4.94 4.45 4.57 7.81 6.98 6.88 4.653333333 7.223333333 276 236 223 139.6666667 245 1.58E-05 0.7997347 GO:0005575///cellular_component GO:0003676///nucleic acid binding GO:0002244///hematopoietic progenitor cell differentiation 66615 66615 'Atg4b' mRNA 1474 1492 1485 25.54 25.44 27.25 22.64 23.46 23.32 26.07666667 23.14 1504 1525 1502 1483.666667 1510.333333 0.89635987 0.013433348 04136///Autophagy - other+++04140///Autophagy - animal GO:0005737///cytoplasm GO:0004175///endopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0097110///scaffold protein binding GO:0000045///autophagosome assembly+++GO:0006508///proteolysis+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0015031///protein transport+++GO:0045732///positive regulation of protein catabolic process+++GO:0051697///protein delipidation 66616 66616 'Snx9' mRNA 729 661 428 11.52 10.18 7.28 9.04 9.74 10.48 9.66 9.753333333 674 698 741 606 704.3333333 0.190851339 0.215264125 05132///Salmonella infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032437///cuticular plate+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0008289///lipid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0071933///Arp2/3 complex binding GO:0000278///mitotic cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0030838///positive regulation of actin filament polymerization+++GO:0036089///cleavage furrow formation+++GO:0043547///positive regulation of GTPase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051301///cell division+++GO:0060988///lipid tube assembly+++GO:0065003///protein-containing complex assembly+++GO:0097320///plasma membrane tubulation 66617 66617 'Ntmt1' mRNA 666 648 625 30.82 30.52 31.87 35.31 36.2 32.99 31.07 34.83333333 832 832 756 646.3333333 806.6666667 0.003272482 0.308223371 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0042054///histone methyltransferase activity+++GO:0071885///N-terminal protein N-methyltransferase activity GO:0006480///N-terminal protein amino acid methylation+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0016571///histone methylation+++GO:0018011///N-terminal peptidyl-alanine methylation+++GO:0018012///N-terminal peptidyl-alanine trimethylation+++GO:0018013///N-terminal peptidyl-glycine methylation+++GO:0018016///N-terminal peptidyl-proline dimethylation+++GO:0032259///methylation+++GO:0035568///N-terminal peptidyl-proline methylation+++GO:0035570///N-terminal peptidyl-serine methylation+++GO:0035572///N-terminal peptidyl-serine dimethylation+++GO:0035573///N-terminal peptidyl-serine trimethylation 666173 666173 'Vps13b' mRNA 1071 1127 1005 4.04 4.18 4.02 2.53 2.02 2.26 4.08 2.27 773 602 669 1067.666667 681.3333333 6.46E-11 -0.660349246 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0015031///protein transport 66618 66618 'Snrnp27' mRNA 782 715 784 62.83 56.92 66.85 50.46 57.71 54.57 62.2 54.24666667 719 801 751 760.3333333 757 0.893965949 -0.01914051 03040///Spliceosome GO:0005634///nucleus GO:0003674///molecular_function GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 666190 666190 'Gm7972' mRNA 80.97 71.37 81.25 0.56 0.48 0.59 0.3 0.15 0.29 0.543333333 0.246666667 45.38 27.1 54.22 77.86333333 42.23333333 0.012621756 -0.897381965 66622 66622 'Ubr7' mRNA 734 687 800 12.35 11.37 14.28 12.34 11.51 11.7 12.66666667 11.85 844 769 775 740.3333333 796 0.525902381 0.088373855 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination 666233 666233 'Gm7995' mRNA 2 4 4 0.1 0.2 0.21 0.04 0 0.04 0.17 0.026666667 1 0 1 3.333333333 0.666666667 0.270520441 -2.345699142 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66624 66624 'Spcs2' mRNA 3457 3597 3444 67.77 69.4 71.58 99.65 102.29 99.06 69.58333333 100.3333333 5848 5863 5629 3499.333333 5780 1.06E-34 0.712177519 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0045047///protein targeting to ER 666244 666244 'Tmsb15b1' mRNA 60.54 66.25 65.09 12.84 14.12 14.66 6.54 4.92 6.74 13.87333333 6.066666667 34.95 25.46 34.57 63.96 31.66 0.004581934 -1.052734716 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003779///actin binding+++GO:0003785///actin monomer binding GO:0007015///actin filament organization+++GO:0030334///regulation of cell migration+++GO:0042989///sequestering of actin monomers 66625 66625 'Pnisr' mRNA 4499 4318 4182 63.62 59.09 62.22 39.31 37.05 39.76 61.64333333 38.70666667 3185 2889 3098 4333 3057.333333 1.99E-17 -0.515281525 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0048786///presynaptic active zone GO:0008150///biological_process 666257 666257 'Zfp660' mRNA 171.69 150.97 165.88 1.61 1.39 1.65 0.41 0.4 0.5 1.55 0.436666667 49.72 47.87 59.29 162.8466667 52.29333333 2.39E-11 -1.66206549 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66626 66626 'Cdip1' mRNA 3150.45 3297.12 3125.51 65.5 67.01 67.67 46.09 48.27 44.32 66.72666667 46.22666667 2624.43 2668.99 2387.29 3191.026667 2560.236667 3.02E-06 -0.329574427 GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0098560///cytoplasmic side of late endosome membrane+++GO:0098574///cytoplasmic side of lysosomal membrane GO:0046872///metal ion binding GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 66627 66627 'Ogfod2' mRNA 685 709 635 25.92 26.45 25.74 20.71 22.15 22.17 26.03666667 21.67666667 621 650 643 676.3333333 638 0.453782435 -0.094013628 GO:0005575///cellular_component "GO:0003674///molecular_function+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" 666279 666279 'Dspp' mRNA 5 1 2 0.06 0.01 0.03 0.01 0.06 0.02 0.033333333 0.03 1 6 2 2.666666667 3 0.930669638 0.173225445 04512///ECM-receptor interaction GO:0001533///cornified envelope+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005916///fascia adherens+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005080///protein kinase C binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0050839///cell adhesion molecule binding+++GO:0097110///scaffold protein binding GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0002934///desmosome organization+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0031214///biomineral tissue development+++GO:0034332///adherens junction organization+++GO:0036305///ameloblast differentiation+++GO:0042060///wound healing+++GO:0042476///odontogenesis+++GO:0043588///skin development+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0045109///intermediate filament organization+++GO:0060231///mesenchymal to epithelial transition+++GO:0060350///endochondral bone morphogenesis+++GO:0060425///lung morphogenesis+++GO:0061448///connective tissue development+++GO:0061914///negative regulation of growth plate cartilage chondrocyte proliferation+++GO:0061978///mandibular condyle articular cartilage development+++GO:0070175///positive regulation of enamel mineralization+++GO:0071460///cellular response to cell-matrix adhesion+++GO:0071895///odontoblast differentiation+++GO:0072050///S-shaped body morphogenesis+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090136///epithelial cell-cell adhesion+++GO:0090280///positive regulation of calcium ion import+++GO:0097186///amelogenesis+++GO:0097187///dentinogenesis+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:1901148///gene expression involved in extracellular matrix organization+++GO:1901329///regulation of odontoblast differentiation+++GO:1902731///negative regulation of chondrocyte proliferation+++GO:1902732///positive regulation of chondrocyte proliferation+++GO:1903011///negative regulation of bone development+++GO:2001054///negative regulation of mesenchymal cell apoptotic process 66628 66628 'Thg1l' mRNA 219 235 228 4.63 5.41 5.29 2.65 2.75 2.64 5.11 2.68 132 135 134 227.3333333 133.6666667 2.92E-05 -0.778230798 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:1990234///transferase complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0008193///tRNA guanylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006400///tRNA modification+++GO:0006979///response to oxidative stress+++GO:0008033///tRNA processing+++GO:0008053///mitochondrial fusion+++GO:0050790///regulation of catalytic activity+++GO:0051289///protein homotetramerization+++GO:0099116///tRNA 5'-end processing+++GO:1990046///stress-induced mitochondrial fusion 66629 66629 'Golph3' mRNA 2408 2395 1079 47.29 45.95 22.06 26.16 22.28 29.78 38.43333333 26.07333333 1608 1308 1708 1960.666667 1541.333333 0.425622025 -0.342986449 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031985///Golgi cisterna+++GO:0032580///Golgi cisterna membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0019899///enzyme binding+++GO:0070273///phosphatidylinositol-4-phosphate binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0009101///glycoprotein biosynthetic process+++GO:0009306///protein secretion+++GO:0010467///gene expression+++GO:0010821///regulation of mitochondrion organization+++GO:0015031///protein transport+++GO:0016477///cell migration+++GO:0030032///lamellipodium assembly+++GO:0032008///positive regulation of TOR signaling+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0043066///negative regulation of apoptotic process+++GO:0045053///protein retention in Golgi apparatus+++GO:0048194///Golgi vesicle budding+++GO:0050714///positive regulation of protein secretion+++GO:0050901///leukocyte tethering or rolling+++GO:0060352///cell adhesion molecule production+++GO:0072752///cellular response to rapamycin+++GO:0090161///Golgi ribbon formation+++GO:0090164///asymmetric Golgi ribbon formation" 66631 66631 'Mfsd14b' mRNA 1849 1981 1777 29.09 30.6 29.56 24.03 22.51 23.46 29.75 23.33333333 1759 1608 1664 1869 1677 0.028446122 -0.167654829 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 666311 666311 'Zscan25' mRNA 35 28 31 0.71 0.56 0.64 0.37 0.34 0.63 0.636666667 0.446666667 21 20 37 31.33333333 26 0.648672956 -0.280849546 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 66632 66632 'Dph6' mRNA 1366.21 1341.13 1292.84 28.23 26.46 27.8 16.71 14.98 15.7 27.49666667 15.79666667 960.28 829.9 867 1333.393333 885.7266667 2.29E-12 -0.603046118 GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0017178///diphthine-ammonia ligase activity GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine 666329 666329 'Gm3317' mRNA 1 0 0 0.04 0 0 0.05 0.03 0 0.013333333 0.026666667 0.89 1 0 0.333333333 0.63 0.998591786 -0.011756601 66634 66634 'Mcm8' mRNA 97.96 77.77 49.96 1.53 1.21 0.83 1.55 1.47 1.14 1.19 1.386666667 114.28 105.31 81.03 75.23 100.2066667 0.204463188 0.424361412 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0042555///MCM complex+++GO:0097362///MCM8-MCM9 complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding+++GO:0032406///MutLbeta complex binding+++GO:0032407///MutSalpha complex binding+++GO:0032408///MutSbeta complex binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007292///female gamete generation+++GO:0032508///DNA duplex unwinding+++GO:0036298///recombinational interstrand cross-link repair+++GO:0048232///male gamete generation+++GO:0050821///protein stabilization+++GO:0071168///protein localization to chromatin 666348 666348 'Apol7e' mRNA 6.5 2.5 3.22 0.16 0.06 0.08 0.13 0.07 0.09 0.1 0.096666667 6 3 4 4.073333333 4.333333333 0.883802264 0.225833177 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0034361///very-low-density lipoprotein particle+++GO:0034364///high-density lipoprotein particle+++GO:0043231///intracellular membrane-bounded organelle GO:0005254///chloride channel activity+++GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0015698///inorganic anion transport+++GO:0042157///lipoprotein metabolic process 66637 66637 'Tsen15' mRNA 601 572 572 32.96 30.99 33.29 33.61 34.76 34.91 32.41333333 34.42666667 703 709 706 581.6666667 706 0.015099841 0.267697558 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity "GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0008150///biological_process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 66641 66641 'Sike1' mRNA 550 553 546 10.85 10.74 11.43 14.82 13.87 13.6 11.00666667 14.09666667 864 790 768 549.6666667 807.3333333 1.86E-07 0.541715774 04622///RIG-I-like receptor signaling pathway GO:0005737///cytoplasm GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding GO:0008150///biological_process 66642 66642 'Ctnnbl1' mRNA 592 643 545 11.99 13.45 11.71 16.02 16.06 16.34 12.38333333 16.14 910 872 850 593.3333333 877.3333333 1.92E-08 0.55436997 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0006915///apoptotic process+++GO:0016445///somatic diversification of immunoglobulins+++GO:0043065///positive regulation of apoptotic process 66643 66643 'Lix1' mRNA 272.67 212.53 236.48 2.85 2.23 2.57 2.01 2.32 1.71 2.55 2.013333333 212.26 244.12 173.21 240.56 209.8633333 0.358416908 -0.206758496 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0097352///autophagosome maturation 66645 66645 'Pspc1' mRNA 275 239 239 6.47 5.54 6 7.67 7.13 7.46 6.003333333 7.42 374 340 353 251 355.6666667 0.001102685 0.490938886 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0042382///paraspeckles GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0042752///regulation of circadian rhythm+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process" 66646 66646 'Rpe' mRNA 879.21 854.75 895.26 18.13 17.11 19.78 18.01 14.51 17.4 18.34 16.64 1007.1 793.07 947.25 876.4066667 915.8066667 0.741194687 0.048723228 00030///Pentose phosphate pathway+++00040///Pentose and glucuronate interconversions+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0003824///catalytic activity+++GO:0004750///ribulose-phosphate 3-epimerase activity+++GO:0016853///isomerase activity+++GO:0016857///racemase and epimerase activity, acting on carbohydrates and derivatives+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048029///monosaccharide binding" "GO:0005975///carbohydrate metabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0009052///pentose-phosphate shunt, non-oxidative branch+++GO:0019323///pentose catabolic process+++GO:0044262///cellular carbohydrate metabolic process" 666468 666468 'Atg4a' mRNA 442 435 439 11.7 11.37 12.35 13.56 14.16 12.51 11.80666667 13.41 588 599 526 438.6666667 571 0.003069641 0.367991018 04136///Autophagy - other+++04140///Autophagy - animal GO:0005737///cytoplasm GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006914///autophagy+++GO:0015031///protein transport 66647 66647 'Nsmce3' mRNA 690 726 217 30.48 31.65 10.17 13.08 26.86 22.43 24.1 20.79 340 681 564 544.3333333 528.3333333 0.981525362 -0.024022945 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0030915///Smc5-Smc6 complex" GO:0005515///protein binding+++GO:0046983///protein dimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031398///positive regulation of protein ubiquitination+++GO:0034644///cellular response to UV+++GO:0040008///regulation of growth+++GO:0071478///cellular response to radiation+++GO:0072711///cellular response to hydroxyurea" 66648 66648 'Tpgs2' mRNA 566.11 595.05 488.48 7.72 7.97 7.16 6.07 6.68 6.22 7.616666667 6.323333333 517.04 551 513 549.88 527.0133333 0.650038079 -0.068827736 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0003674///molecular_function GO:0008150///biological_process+++GO:0018095///protein polyglutamylation 66650 66650 'Nepn' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0046696///lipopolysaccharide receptor complex GO:0001530///lipopolysaccharide binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002718///regulation of cytokine production involved in immune response+++GO:0030198///extracellular matrix organization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway 666501 666501 'Gm8137' mRNA 1.16 1.61 1.09 0.18 0.24 0.17 0.41 0.38 0.35 0.196666667 0.38 3.12 2.81 2.55 1.286666667 2.826666667 0.602813454 1.206776585 666528 666528 'Zfp541' mRNA 0 1 3 0 0.01 0.04 0.06 0.03 0 0.016666667 0.03 6 3 0 1.333333333 3 0.646711697 1.11265362 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016575///histone deacetylation+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 66653 66653 'Brf2' mRNA 248 295 228 8.48 10.07 8.33 6.72 5.45 6.11 8.96 6.093333333 216 189 182 257 195.6666667 0.026377893 -0.402756877 GO:0000126///transcription factor TFIIIB complex+++GO:0005634///nucleus+++GO:0097550///transcriptional preinitiation complex GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0017025///TBP-class protein binding+++GO:0046872///metal ion binding "GO:0006352///DNA-templated transcription, initiation+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0034599///cellular response to oxidative stress+++GO:0070897///transcription preinitiation complex assembly" 666532 666532 'Zfp991' mRNA 495.15 457.37 563.2 6.48 5.9 7.87 7.34 7.14 7.23 6.75 7.236666667 642.53 617.98 615.42 505.24 625.31 0.03354825 0.290005425 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 66654 66654 'Tex12' mRNA 1 1 2 0.12 0.12 0.26 0.21 0.55 0.11 0.166666667 0.29 2 5 1 1.333333333 2.666666667 0.658653795 0.982243466 GO:0000795///synaptonemal complex+++GO:0000801///central element+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0005515///protein binding GO:0000711///meiotic DNA repair synthesis+++GO:0007130///synaptonemal complex assembly+++GO:0051321///meiotic cell cycle 66656 66656 'Eef1d' mRNA 2488 2408 2347 135.75 130.74 133.89 152.98 153.64 162.3 133.46 156.3066667 3038 2966 3087 2414.333333 3030.333333 1.18E-06 0.316174788 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005853///eukaryotic translation elongation factor 1 complex+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0003677///DNA binding+++GO:0003746///translation elongation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031072///heat shock protein binding+++GO:0033613///activating transcription factor binding GO:0006412///translation+++GO:0006414///translational elongation+++GO:0009299///mRNA transcription+++GO:0010941///regulation of cell death+++GO:0050790///regulation of catalytic activity+++GO:0071479///cellular response to ionizing radiation 66658 66658 'Ccdc51' mRNA 170 194 148 3.97 4.46 3.66 4.14 3.97 3.46 4.03 3.856666667 204 191 165 170.6666667 186.6666667 0.625524269 0.12066648 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0034705///potassium channel complex GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport 666584 666584 'BC024063' mRNA 278.77 256.79 238.31 3.19 2.89 2.9 1.11 1.31 1.26 2.993333333 1.226666667 111.22 128.37 122.3 257.9566667 120.63 1.85E-09 -1.105757378 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 66659 66659 'Acp6' mRNA 761 780 728 25.05 25.31 25.43 17.5 18.52 17.58 25.26333333 17.86666667 611 631 594 756.3333333 612 0.002549855 -0.316346815 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003993///acid phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0052642///lysophosphatidic acid phosphatase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0016311///dephosphorylation+++GO:2001311///lysobisphosphatidic acid metabolic process 66660 66660 'Sltm' mRNA 1177 1210 1094 16.84 17.26 16.69 15.75 14.86 15.49 16.93 15.36666667 1258 1167 1197 1160.333333 1207.333333 0.664230236 0.046283411 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030425///dendrite+++GO:0036126///sperm flagellum+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005008///hepatocyte growth factor-activated receptor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017154///semaphorin receptor activity+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0043274///phospholipase binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001764///neuron migration+++GO:0001886///endothelial cell morphogenesis+++GO:0001889///liver development+++GO:0001890///placenta development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0006909///phagocytosis+++GO:0006915///apoptotic process+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0010976///positive regulation of neuron projection development+++GO:0014812///muscle cell migration+++GO:0014902///myotube differentiation+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030182///neuron differentiation+++GO:0030317///flagellated sperm motility+++GO:0030534///adult behavior+++GO:0031016///pancreas development+++GO:0031116///positive regulation of microtubule polymerization+++GO:0032675///regulation of interleukin-6 production+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0042593///glucose homeostasis+++GO:0043410///positive regulation of MAPK cascade+++GO:0045740///positive regulation of DNA replication+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046777///protein autophosphorylation+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0050684///regulation of mRNA processing+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0050918///positive chemotaxis+++GO:0051450///myoblast proliferation+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0055013///cardiac muscle cell development+++GO:0060048///cardiac muscle contraction+++GO:0060079///excitatory postsynaptic potential+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:0061436///establishment of skin barrier+++GO:0070495///negative regulation of thrombin-activated receptor signaling pathway+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0071635///negative regulation of transforming growth factor beta production+++GO:0072593///reactive oxygen species metabolic process+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity+++GO:2001028///positive regulation of endothelial cell chemotaxis 66661 66661 'Srp72' mRNA 1422 1488 1321 21.41 22.04 21.1 24.46 21.9 23.81 21.51666667 23.39 1869 1635 1762 1410.333333 1755.333333 8.83E-05 0.304491988 03060///Protein export "GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0048500///signal recognition particle" GO:0005047///signal recognition particle binding+++GO:0008312///7S RNA binding+++GO:0030911///TPR domain binding+++GO:0043022///ribosome binding GO:0006614///SRP-dependent cotranslational protein targeting to membrane 66663 66663 'Uba5' mRNA 841 920 266 19.55 21.05 6.57 8.97 17.01 16.22 15.72333333 14.06666667 444 821 776 675.6666667 680.3333333 0.97566161 0.028735497 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0071566///UFM1 activating enzyme activity GO:0030218///erythrocyte differentiation+++GO:0030219///megakaryocyte differentiation+++GO:0032446///protein modification by small protein conjugation+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0050905///neuromuscular process+++GO:0061709///reticulophagy+++GO:0071569///protein ufmylation+++GO:1990592///protein K69-linked ufmylation 66664 66664 'Tmem41a' mRNA 882 915 889 38.96 39.89 41.67 17.2 17.23 18.02 40.17333333 17.48333333 447 437 453 895.3333333 445.6666667 1.41E-23 -1.018648988 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66665 66665 'Msantd3' mRNA 110 92 76 3.5 2.61 2.69 3.05 3.35 4.38 2.933333333 3.593333333 107 112 144 92.66666667 121 0.182739789 0.378594687 GO:0005575///cellular_component GO:0042802///identical protein binding GO:0008150///biological_process 66667 66667 'Hspbap1' mRNA 196 171 183 3.34 2.67 3.35 3.72 3.41 2.79 3.12 3.306666667 237 215 185 183.3333333 212.3333333 0.362726709 0.19810743 GO:0005575///cellular_component+++GO:0005737///cytoplasm "GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors" 666704 666704 'Samd1' mRNA 141 122 129 3.51 2.99 3.41 2.71 3.11 3.58 3.303333333 3.133333333 125 140 160 130.6666667 141.6666667 0.725458338 0.105601033 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0042393///histone binding "GO:0045892///negative regulation of transcription, DNA-templated" 66671 66671 'Ccnh' mRNA 833 832 839 22.83 22.82 25.2 22.14 23.61 23.09 23.61666667 22.94666667 911 952 900 834.6666667 921 0.234608068 0.129822147 03022///Basal transcription factors+++03420///Nucleotide excision repair+++04110///Cell cycle GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005675///transcription factor TFIIH holo complex+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0070516///CAK-ERCC2 complex+++GO:0070985///transcription factor TFIIK complex GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0016301///kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007049///cell cycle+++GO:0050790///regulation of catalytic activity+++GO:0050821///protein stabilization+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain" 66673 66673 'Sorcs3' mRNA 824 770 656 7.78 7.15 6.57 6.22 7.05 6.44 7.166666667 6.57 759 840 761 750 786.6666667 0.665554617 0.061296216 GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0007612///learning+++GO:0007613///memory+++GO:1900452///regulation of long-term synaptic depression 666731 666731 'Trim43c' mRNA 69.69 46.57 37.08 0.46 0.3 0.26 0.32 0.25 0.37 0.34 0.313333333 52.68 43.44 63.87 51.11333333 53.33 0.918161694 0.050076058 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 666738 666738 'Gm8264' mRNA 1.16 1.61 1.09 0.18 0.24 0.17 0.41 0.38 0.35 0.196666667 0.38 3.12 2.81 2.55 1.286666667 2.826666667 0.602813454 1.206776585 66674 66674 'Spryd7' mRNA 1083 1155 1104 14.09 14.78 15.24 9.13 8.41 8.73 14.70333333 8.756666667 807 726 747 1114 760 6.44E-10 -0.564470459 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 666744 666744 'Gm8267' mRNA 1 1 0 0.05 0.05 0 0 0 0 0.033333333 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 666747 666747 'Trim43b' mRNA 3 3.24 2 0.07 0.08 0.05 0.02 0.08 0.09 0.066666667 0.063333333 1.08 3.46 4 2.746666667 2.846666667 0.999197613 0.002107485 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 66676 66676 'Tmed7' mRNA 1121 1192 771 17.67 18.49 12.9 20.35 16.06 20.44 16.35333333 18.95 1485 1145 1445 1028 1358.333333 0.002336749 0.396887295 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport 666765 666765 'Gm8279' mRNA 0 0.31 1 0 0.01 0.02 0 0.02 0.02 0.01 0.013333333 0 1 1 0.436666667 0.666666667 0.863090843 0.898087804 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66679 66679 'Rae1' mRNA 1210 1183 1199 41.46 40.2 43.76 39.89 40.51 40.31 41.80666667 40.23666667 1322 1349 1322 1197.333333 1331 0.129176196 0.140384108 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A GO:0000922///spindle pole+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0097431///mitotic spindle pole GO:0003723///RNA binding+++GO:0043130///ubiquitin binding GO:0000972///transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0071407///cellular response to organic cyclic compound 666790 666790 'Gm8290' mRNA 62.22 80.4 73.63 0.59 0.75 0.74 0.37 0.35 0.33 0.693333333 0.35 44.17 41.21 38.22 72.08333333 41.2 0.017293461 -0.818586332 666794 666794 'Rbm24' mRNA 1134 1126 977 19.23 18.78 17.57 2.36 1.8 2.4 18.52666667 2.186666667 160 119 158 1079 145.6666667 1.46E-118 -2.89949957 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0097157///pre-mRNA intronic binding+++GO:1990715///mRNA CDS binding+++GO:1990825///sequence-specific mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0003197///endocardial cushion development+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008380///RNA splicing+++GO:0010830///regulation of myotube differentiation+++GO:0010831///positive regulation of myotube differentiation+++GO:0030154///cell differentiation+++GO:0043488///regulation of mRNA stability+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048255///mRNA stabilization+++GO:0061157///mRNA destabilization+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:1902811///positive regulation of skeletal muscle fiber differentiation+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization+++GO:2000738///positive regulation of stem cell differentiation+++GO:2000766///negative regulation of cytoplasmic translation" 66680 66680 'Oser1' mRNA 1222 1257 1197 45.94 46.61 47.75 51.38 55.83 51.76 46.76666667 52.99 1570 1665 1530 1225.333333 1588.333333 1.09E-05 0.363274368 GO:0005575///cellular_component GO:0003674///molecular_function GO:0070301///cellular response to hydrogen peroxide 666808 666808 'Gm10410' mRNA 3 0 0 0.12 0 0 0.03 0 0.05 0.04 0.026666667 1 0 1.36 1 0.786666667 0.876679435 -0.58285425 66681 66681 'Pgm2' mRNA 299 321 323 7.03 7.4 8.03 13.72 12.24 13.18 7.486666667 13.04666667 671 587 625 314.3333333 627.6666667 8.47E-16 0.983849294 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00052///Galactose metabolism+++00230///Purine metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm "GO:0000287///magnesium ion binding+++GO:0004614///phosphoglucomutase activity+++GO:0008973///phosphopentomutase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0046386///deoxyribose phosphate catabolic process+++GO:0071704///organic substance metabolic process 66682 66682 'Trappc5' mRNA 1116.18 1132.14 1103.8 31.19 31.16 32.72 22.93 23.39 22.85 31.69 23.05666667 943.37 939.81 910.06 1117.373333 931.08 0.002251101 -0.275288153 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0030008///TRAPP complex+++GO:1990070///TRAPPI protein complex+++GO:1990071///TRAPPII protein complex+++GO:1990072///TRAPPIII protein complex GO:0005515///protein binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048193///Golgi vesicle transport 66684 66684 'Tceal8' mRNA 1550 1611 1544 38.64 39.55 40.81 46.34 44.85 44.07 39.66666667 45.08666667 2138 2021 1968 1568.333333 2042.333333 4.67E-07 0.36866766 GO:0005634///nucleus GO:0050699///WW domain binding 666842 666842 'Gm14692' mRNA 4.61 3 2 0.16 0.11 0.12 0.5 0.35 0.42 0.13 0.423333333 16 11 13 3.203333333 13.33333333 0.025829556 2.143364432 GO:0000795///synaptonemal complex GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 66686 66686 'Dcbld1' mRNA 514 579 418 9.39 10.37 8.11 4.72 5.7 5.17 9.29 5.196666667 297 352 316 503.6666667 321.6666667 6.15E-06 -0.651725576 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0072562///blood microparticle GO:0004252///serine-type endopeptidase activity GO:0031638///zymogen activation 66687 66687 'Tbc1d15' mRNA 1178 1209 1180 18.8 19.32 20.35 21.79 22.42 21.38 19.49 21.86333333 1573 1552 1469 1189 1531.333333 1.50E-05 0.352809818 04137///Mitophagy - animal GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0043087///regulation of GTPase activity+++GO:0090630///activation of GTPase activity 66689 66689 'Klhl28' mRNA 388 434 403 4.67 5.19 5.43 5.05 4.15 4.19 5.096666667 4.463333333 449 380 399 408.3333333 409.3333333 0.960236617 -0.009429313 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66690 66690 'Tmem186' mRNA 630 710 717 12.08 13.39 14.58 9.9 11.42 9.65 13.35 10.32333333 593 670 560 685.6666667 607.6666667 0.170367597 -0.187033989 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 666907 666907 'Ms4a4a' mRNA 159.92 207.8 175.45 9.02 11.48 10.59 289.01 239.24 267.29 10.36333333 265.18 6112.81 4848.16 5422.38 181.0566667 5461.116667 0 4.907606217 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft GO:0003674///molecular_function GO:0008150///biological_process 66691 66691 'Gapvd1' mRNA 1480.77 1579.23 1504.33 12.19 12.91 12.8 13.71 12.08 13.4 12.63333333 13.06333333 1906.08 1657.39 1798.27 1521.443333 1787.246667 0.007585756 0.219516212 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0032794///GTPase activating protein binding GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0016192///vesicle-mediated transport+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051223///regulation of protein transport 666927 666927 'Gm12887' mRNA 0 1 0 0 0.11 0 0 0 0 0.036666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 666931 666931 'Gm10573' mRNA 1 1 0 0.33 0.33 0 0 0 0 0.22 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 666938 666938 'Bend4' mRNA 125 122 116 0.82 0.8 0.82 0.58 0.48 0.49 0.813333333 0.516666667 101 82 82 121 88.33333333 0.070522798 -0.466782047 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 66694 66694 'Uqcrfs1' mRNA 3290 3418 3280 151.33 155.18 160.07 145.95 153.98 148.3 155.5266667 149.41 3643 3749 3580 3329.333333 3657.333333 0.073899317 0.123941949 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain "GO:0005515///protein binding+++GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0016491///oxidoreductase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0009725///response to hormone+++GO:0022904///respiratory electron transport chain+++GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0042493///response to drug+++GO:0046677///response to antibiotic+++GO:1902600///proton transmembrane transport" 66695 66695 'Aspn' mRNA 57.68 65.86 45.68 1.37 1.54 1.15 1.49 1.41 0.9 1.353333333 1.266666667 71.77 66.77 42.18 56.40666667 60.24 0.857122556 0.092723017 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0042995///cell projection+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005518///collagen binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance GO:0030282///bone mineralization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031214///biomineral tissue development+++GO:0070171///negative regulation of tooth mineralization 66696 66696 'Snx31' mRNA 26 12 10 0.58 0.28 0.25 0.21 0.23 0.21 0.37 0.216666667 11 12 10 16 11 0.523388691 -0.542891738 GO:0005769///early endosome+++GO:0032991///protein-containing complex GO:0035091///phosphatidylinositol binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling 66700 66700 'Chmp3' mRNA 2477.85 2619.28 2624.37 54.74 56.2 63.46 60 58.53 64.38 58.13333333 60.97 3181.11 2947.17 3130.84 2573.833333 3086.373333 6.25E-04 0.248452403 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0031210///phosphatidylcholine binding+++GO:0042802///identical protein binding+++GO:1990381///ubiquitin-specific protease binding" GO:0007034///vacuolar transport+++GO:0007049///cell cycle+++GO:0008333///endosome to lysosome transport+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032467///positive regulation of cytokinesis+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0045324///late endosome to vacuole transport+++GO:0046761///viral budding from plasma membrane+++GO:0050792///regulation of viral process+++GO:0051036///regulation of endosome size+++GO:0051258///protein polymerization+++GO:0051301///cell division+++GO:0061763///multivesicular body-lysosome fusion+++GO:0061952///midbody abscission+++GO:1902187///negative regulation of viral release from host cell+++GO:1902188///positive regulation of viral release from host cell+++GO:2000641///regulation of early endosome to late endosome transport 66701 66701 'Spryd4' mRNA 276 234 229 10.32 8.63 9.08 12.56 12.4 12.44 9.343333333 12.46666667 386 372 370 246.3333333 376 5.09E-05 0.59926917 GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 667034 667034 'Pnp2' mRNA 13.31 7 6.69 0.67 0.32 0.3 2.37 3.39 2.36 0.43 2.706666667 54.36 76.21 53.04 9 61.20333333 1.29E-08 2.811032019 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001882///nucleoside binding+++GO:0002060///purine nucleobase binding+++GO:0003824///catalytic activity+++GO:0004731///purine-nucleoside phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042301///phosphate ion binding+++GO:0042802///identical protein binding+++GO:0047975///guanosine phosphorylase activity" GO:0006139///nucleobase-containing compound metabolic process+++GO:0006738///nicotinamide riboside catabolic process+++GO:0006955///immune response+++GO:0009116///nucleoside metabolic process+++GO:0009165///nucleotide biosynthetic process+++GO:0009410///response to xenobiotic stimulus+++GO:0032743///positive regulation of interleukin-2 production+++GO:0042278///purine nucleoside metabolic process+++GO:0042493///response to drug+++GO:0043101///purine-containing compound salvage 66704 66704 'Rbm4b' mRNA 1260.92 1333.72 1188.8 23.01 26.66 23.36 18.67 18.98 18.42 24.34333333 18.69 1067.85 1033.88 991.56 1261.146667 1031.096667 3.74E-04 -0.301338635 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006417///regulation of translation+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0010628///positive regulation of gene expression+++GO:0032922///circadian regulation of gene expression+++GO:0043153///entrainment of circadian clock by photoperiod" 66705 66705 'Dnase1l2' mRNA 33 29 25 1.28 1.18 1.06 0.96 0.99 0.75 1.173333333 0.9 26 27 23 29 25.33333333 0.747893353 -0.20337649 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004530///deoxyribonuclease I activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000737///DNA catabolic process, endonucleolytic+++GO:0001942///hair follicle development+++GO:0003335///corneocyte development+++GO:0006308///DNA catabolic process" 667055 667055 'Unc93a2' mRNA 4.64 6.8 2 0.17 0.23 0.08 0 0.03 0 0.16 0.01 0 1 0 4.48 0.333333333 0.105792666 -3.474469404 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66706 66706 'Ndufaf3' mRNA 890 788 766 36.78 32.13 33.59 27.17 26.63 27.16 34.16666667 26.98666667 755 722 730 814.6666667 735.6666667 0.154559647 -0.158267895 04714///Thermogenesis GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 667060 667060 'Vmn2r5' mRNA 0 1.99 1.5 0 0.04 0.03 0 0 0 0.023333333 0 0 0 0 1.163333333 0 0.747865658 -1.883366447 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell 667063 667063 'Gm8439' mRNA 0 0 2 0 0 0.49 0.2 0.42 2.12 0.163333333 0.913333333 1 2 10 0.666666667 4.333333333 0.214955784 2.65455829 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66707 66707 'Nkapl' mRNA 59 50 37 2.41 2.01 1.6 0.99 1.24 1.36 2.006666667 1.196666667 28 34 37 48.66666667 33 0.197284964 -0.563985824 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003682///chromatin binding GO:0007283///spermatogenesis+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation 667103 667103 'Gm13570' mRNA 9 7 6 1.14 0.89 0.81 0.45 0.11 0.46 0.946666667 0.34 4 1 4 7.333333333 3 0.301833971 -1.302291932 05415///Diabetic cardiomyopathy 66711 66711 'Sbds' mRNA 1568 1663 1515 59.62 62.48 61.11 56.88 58.95 57.66 61.07 57.83 1714 1735 1674 1582 1707.666667 0.238848521 0.099576944 03008///Ribosome biogenesis in eukaryotes GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0008017///microtubule binding+++GO:0019843///rRNA binding+++GO:0043022///ribosome binding GO:0001833///inner cell mass cell proliferation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006364///rRNA processing+++GO:0007052///mitotic spindle organization+++GO:0030282///bone mineralization+++GO:0030595///leukocyte chemotaxis+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0048539///bone marrow development 667118 667118 'Zbed6' mRNA 142 133 125 1.52 1.4 1.41 1.97 1.63 1.91 1.443333333 1.836666667 213 172 200 133.3333333 195 0.008284625 0.536357866 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001835///blastocyst hatching+++GO:0003309///type B pancreatic cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045787///positive regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0060548///negative regulation of cell death+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus" 66713 66713 'Actr2' mRNA 1465 1440 1314 21.65 20.94 20.6 49.52 44.41 49.98 21.06333333 47.97 3856 3378 3769 1406.333333 3667.666667 2.46E-90 1.371641654 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0005938///cell cortex+++GO:0014069///postsynaptic density+++GO:0030027///lamellipodium+++GO:0030478///actin cap+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0061825///podosome core+++GO:0098794///postsynapse GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding GO:0007163///establishment or maintenance of cell polarity+++GO:0008306///associative learning+++GO:0008356///asymmetric cell division+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0016482///cytosolic transport+++GO:0030036///actin cytoskeleton organization+++GO:0033206///meiotic cytokinesis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0035902///response to immobilization stress+++GO:0035984///cellular response to trichostatin A+++GO:0045471///response to ethanol+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0060271///cilium assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071346///cellular response to interferon-gamma+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 66714 66714 '4921524J17Rik' mRNA 474 448 473 17.4 16.22 18.42 19.27 18.27 17.74 17.34666667 18.42666667 603 558 537 465 566 0.0321747 0.269823681 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66715 66715 'Henmt1' mRNA 25 23 12 0.66 0.73 0.31 0.33 0.19 0.14 0.566666667 0.22 14 6 7 20 9 0.119450115 -1.157966299 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043186///P granule GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0090486///small RNA 2'-O-methyltransferase GO:0001510///RNA methylation+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0032259///methylation+++GO:0034587///piRNA metabolic process 66717 66717 'Ccdc96' mRNA 432 435 352 6.55 6.48 5.66 0.82 1.17 0.99 6.23 0.993333333 62 87 73 406.3333333 74 8.74E-41 -2.463047287 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0036064///ciliary basal body GO:0003674///molecular_function GO:0060271///cilium assembly 66720 66720 'Klhl10' mRNA 33 42 24 1.19 1.57 0.95 0.26 0.47 0.69 1.236666667 0.473333333 12 12 21 33 15 0.041141215 -1.139019222 GO:0005737///cytoplasm GO:0005515///protein binding GO:0000902///cell morphogenesis+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0048808///male genitalia morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue 667214 667214 '9930111J21Rik1' mRNA 185.69 171.8 144.58 2.6 2.37 2.15 6.54 6.16 6.98 2.373333333 6.56 537.79 495.12 555.98 167.3566667 529.63 1.36E-31 1.657168141 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006952///defense response+++GO:0035458///cellular response to interferon-beta 66722 66722 'Spag16' mRNA 544 655 559 13.75 15.05 14.69 0.91 0.57 0.8 14.49666667 0.76 43 25 45 586 37.66666667 8.04E-89 -3.971405766 GO:0002177///manchette+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:1990716///axonemal central apparatus GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0007288///sperm axoneme assembly+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0051012///microtubule sliding+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0090660///cerebrospinal fluid circulation+++GO:0097231///cell motility in response to calcium ion 66724 66724 'Tab3' mRNA 146 178 147 1.21 1.46 1.3 1.08 0.95 1.43 1.323333333 1.153333333 149 129 193 157 157 0.97798309 -0.00998781 04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0008270///zinc ion binding+++GO:0016301///kinase activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0000187///activation of MAPK activity+++GO:0016310///phosphorylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling 66725 66725 'Lrrk2' mRNA 447 426 398 2.79 2.63 2.63 3.61 2.83 3.23 2.683333333 3.223333333 666 507 578 423.6666667 583.6666667 5.08E-04 0.449408367 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016234///inclusion body+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032473///cytoplasmic side of mitochondrial outer membrane+++GO:0032839///dendrite cytoplasm+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044753///amphisome+++GO:0044754///autolysosome+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0070971///endoplasmic reticulum exit site+++GO:0097487///multivesicular body, internal vesicle+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099400///caveola neck+++GO:0099523///presynaptic cytosol+++GO:1990904///ribonucleoprotein complex+++GO:1990909///Wnt signalosome" GO:0000149///SNARE binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003779///actin binding+++GO:0003924///GTPase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0015631///tubulin binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0017075///syntaxin-1 binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030276///clathrin binding+++GO:0031267///small GTPase binding+++GO:0034211///GTP-dependent protein kinase activity+++GO:0036479///peroxidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0051018///protein kinase A binding+++GO:1904713///beta-catenin destruction complex binding "GO:0000165///MAPK cascade+++GO:0000186///activation of MAPKK activity+++GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006468///protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006606///protein import into nucleus+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007040///lysosome organization+++GO:0007165///signal transduction+++GO:0007254///JNK cascade+++GO:0007283///spermatogenesis+++GO:0007528///neuromuscular junction development+++GO:0008340///determination of adult lifespan+++GO:0009267///cellular response to starvation+++GO:0010468///regulation of gene expression+++GO:0010506///regulation of autophagy+++GO:0010508///positive regulation of autophagy+++GO:0010738///regulation of protein kinase A signaling+++GO:0010955///negative regulation of protein processing+++GO:0010977///negative regulation of neuron projection development+++GO:0014041///regulation of neuron maturation+++GO:0016242///negative regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0021756///striatum development+++GO:0021772///olfactory bulb development+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0030154///cell differentiation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032091///negative regulation of protein binding+++GO:0032092///positive regulation of protein binding+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034260///negative regulation of GTPase activity+++GO:0034599///cellular response to oxidative stress+++GO:0034613///cellular protein localization+++GO:0035556///intracellular signal transduction+++GO:0035564///regulation of kidney size+++GO:0035640///exploration behavior+++GO:0035641///locomotory exploration behavior+++GO:0035751///regulation of lysosomal lumen pH+++GO:0036465///synaptic vesicle recycling+++GO:0040012///regulation of locomotion+++GO:0042391///regulation of membrane potential+++GO:0043068///positive regulation of programmed cell death+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0046039///GTP metabolic process+++GO:0046777///protein autophosphorylation+++GO:0048312///intracellular distribution of mitochondria+++GO:0048812///neuron projection morphogenesis+++GO:0051646///mitochondrion localization+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051900///regulation of mitochondrial depolarization+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0060159///regulation of dopamine receptor signaling pathway+++GO:0060161///positive regulation of dopamine receptor signaling pathway+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0070997///neuron death+++GO:0071287///cellular response to manganese ion+++GO:0071407///cellular response to organic cyclic compound+++GO:0072593///reactive oxygen species metabolic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0140058///neuron projection arborization+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1901214///regulation of neuron death+++GO:1901215///negative regulation of neuron death+++GO:1901727///positive regulation of histone deacetylase activity+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1902499///positive regulation of protein autoubiquitination+++GO:1902692///regulation of neuroblast proliferation+++GO:1902803///regulation of synaptic vesicle transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:1903125///negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1903215///negative regulation of protein targeting to mitochondrion+++GO:1903351///cellular response to dopamine+++GO:1903980///positive regulation of microglial cell activation+++GO:1904887///Wnt signalosome assembly+++GO:1905279///regulation of retrograde transport, endosome to Golgi+++GO:1905289///regulation of CAMKK-AMPK signaling cascade+++GO:2000172///regulation of branching morphogenesis of a nerve+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000469///negative regulation of peroxidase activity" 667250 667250 'Gm12657' mRNA 177.59 171.93 165.69 11.67 11.18 11.56 14.11 11.36 15.95 11.47 13.80666667 245.99 193.14 268.85 171.7366667 235.9933333 0.022862717 0.448099122 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus 66727 66727 'Plaat5' mRNA 5 8 8 0.2 0.18 0.19 0.08 0 0 0.19 0.026666667 4 0 0 7 1.333333333 0.119263046 -2.427151755 GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004623///phospholipase A2 activity+++GO:0008970///phospholipase A1 activity+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0070292///N-acylphosphatidylethanolamine metabolic process 667277 667277 'C1rb' mRNA 9.01 3.08 10.42 0.23 0.08 0.29 0.79 0.62 0.77 0.2 0.726666667 34.82 26.51 32.99 7.503333333 31.44 0.001399349 2.040457525 04145///Phagosome+++04610///Complement and coagulation cascades+++05133///Pertussis+++05150///Staphylococcus aureus infection+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005615///extracellular space+++GO:0072562///blood microparticle GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006958///complement activation, classical pathway+++GO:0031638///zymogen activation+++GO:0045087///innate immune response" 667281 667281 'H60b' mRNA 0 2 2 0 0.13 0.14 0.83 1.22 1.47 0.09 1.173333333 14 20 24 1.333333333 19.33333333 2.73E-04 3.846123353 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046703///natural killer cell lectin-like receptor binding GO:0002376///immune system process+++GO:0006955///immune response+++GO:0042267///natural killer cell mediated cytotoxicity 66729 66729 'Ankrd61' mRNA 11 13 3 0.37 0.46 0.13 0.14 0.06 0.24 0.32 0.146666667 4 2 8 9 4.666666667 0.436131772 -0.938109482 GO:0005654///nucleoplasm GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 667306 667306 'Gm11634' mRNA 4 1 3 0.32 0.08 0.29 0 0 0.14 0.23 0.046666667 0 0 2 2.666666667 0.666666667 0.418168026 -2.015833475 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66733 66733 'Kcng4' mRNA 88 112 95 1.24 1.56 1.4 4.79 5.67 5.78 1.4 5.413333333 391 454 458 98.33333333 434.3333333 1.60E-35 2.134060091 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0044325///ion channel binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 66734 66734 'Map1lc3a' mRNA 3854 3792 3489 233.32 226.95 224.12 186.93 199.18 194.99 228.13 193.7 3541 3678 3570 3711.666667 3596.333333 0.457340331 -0.055565679 04137///Mitophagy - animal+++04140///Autophagy - animal+++04216///Ferroptosis+++04371///Apelin signaling pathway+++04621///NOD-like receptor signaling pathway+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0012505///endomembrane system+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044754///autolysosome+++GO:0045202///synapse GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008017///microtubule binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0031625///ubiquitin protein ligase binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0006995///cellular response to nitrogen starvation+++GO:0009267///cellular response to starvation+++GO:0010040///response to iron(II) ion+++GO:0010288///response to lead ion+++GO:0016236///macroautophagy+++GO:0031667///response to nutrient levels+++GO:0034198///cellular response to amino acid starvation+++GO:0043278///response to morphine+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071280///cellular response to copper ion+++GO:0097352///autophagosome maturation 66736 66736 'Emc2' mRNA 953 1004 910 46.68 48.56 47.29 54.24 54.12 56.22 47.51 54.86 1271 1237 1274 955.6666667 1260.666667 3.25E-06 0.388836815 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 667370 667370 'Ifit3b' mRNA 1192.08 1212.51 1160.4 33.78 33.85 34.86 43.14 44.31 41.09 34.16333333 42.84666667 1753.08 1755.7 1614.43 1188.33 1707.736667 9.34E-11 0.511573065 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0042802///identical protein binding GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0035457///cellular response to interferon-alpha+++GO:0043066///negative regulation of apoptotic process+++GO:0051607///defense response to virus 667373 667373 'Ifit1bl1' mRNA 25 23 11.38 0.61 0.48 0.28 0.95 1.32 1.03 0.456666667 1.1 45 60.36 48 19.79333333 51.12 0.002602281 1.376506827 05160///Hepatitis C GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003723///RNA binding GO:0009615///response to virus+++GO:0050688///regulation of defense response to virus+++GO:0051607///defense response to virus+++GO:0071357///cellular response to type I interferon+++GO:0071360///cellular response to exogenous dsRNA 667414 667414 'Gm8618' mRNA 2.01 0 0 0.33 0 0 0 0.3 0.3 0.11 0.2 0 2 2 0.67 1.333333333 0.780826139 1.02304122 66743 66743 'Rnf220' mRNA 619 565 509 17.91 15.98 15.44 12.81 10.07 12.51 16.44333333 11.79666667 511 394 477 564.3333333 460.6666667 0.023896304 -0.304132023 GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0003358///noradrenergic neuron development+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000677///regulation of transcription regulatory region DNA binding 66748 66748 'Erich2' mRNA 74 96 81 3.69 4.72 4.13 1.05 1.1 2.03 4.18 1.393333333 27 24 39 83.66666667 30 2.06E-05 -1.490197817 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66753 66753 'Erlec1' mRNA 1357.77 1344.16 1298.41 22.21 21.92 23.56 26.45 27.04 27.13 22.56333333 26.87333333 1708.31 1637.31 1608.52 1333.446667 1651.38 1.14E-04 0.296745289 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005515///protein binding+++GO:0051082///unfolded protein binding "GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 667552 667552 'Gm8700' mRNA 48.15 60.41 43.1 0.91 1.13 0.87 0.06 0.11 0.08 0.97 0.083333333 3.39 6.42 4.81 50.55333333 4.873333333 2.54E-09 -3.542589935 66756 66756 'Cfap97' mRNA 628 607 579 6.76 6.47 6.62 5.87 5.87 5.12 6.616666667 5.62 617 601 533 604.6666667 583.6666667 0.671660644 -0.062498949 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66757 66757 'Adat2' mRNA 156.56 125.22 126.91 9.01 8.4 7.02 5.94 6.4 6.04 8.143333333 6.126666667 128.22 131.86 121.54 136.23 127.2066667 0.711042761 -0.109630238 GO:0003824///catalytic activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0052717///tRNA-specific adenosine-34 deaminase activity GO:0002100///tRNA wobble adenosine to inosine editing+++GO:0008033///tRNA processing 66758 66758 'Zfp474' mRNA 551 553 535 15.24 15.13 15.8 1.15 1.38 1.21 15.39 1.246666667 47 52 49 546.3333333 49.33333333 3.72E-86 -3.480696534 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 66766 66766 'Tmem239' mRNA 0 1 0 0 0.05 0 0.05 0 0.05 0.016666667 0.033333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873430513 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 667663 667663 'Myo3a' mRNA 184 199 190 1.93 2.06 2.12 0.21 0.39 0.32 2.036666667 0.306666667 23 42 34 191 33 2.64E-21 -2.542094426 04745///Phototransduction - fly GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016459///myosin complex+++GO:0030175///filopodium+++GO:0031941///filamentous actin+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0032433///filopodium tip+++GO:0042995///cell projection GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0043531///ADP binding+++GO:0051015///actin filament binding+++GO:0060002///plus-end directed microfilament motor activity GO:0006468///protein phosphorylation+++GO:0007601///visual perception+++GO:0007605///sensory perception of sound+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030832///regulation of actin filament length+++GO:0046777///protein autophosphorylation+++GO:0048839///inner ear development+++GO:0050896///response to stimulus+++GO:0051491///positive regulation of filopodium assembly+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0090103///cochlea morphogenesis 667666 667666 'Zfp600' mRNA 2.52 2.1 1.26 0.03 0.03 0.02 0.06 0 0.05 0.026666667 0.036666667 5.8 0 4.42 1.96 3.406666667 0.712312441 0.834539367 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 66768 66768 'Pacrgl' mRNA 220 274 109 8.91 10.95 4.69 2.79 5.6 4.01 8.183333333 4.133333333 79 155 110 201 114.6666667 0.011630804 -0.798498812 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 667693 667693 'Gm8765' mRNA 51.37 66.4 48.98 0.93 1.59 1.18 0.09 0.15 0.09 1.233333333 0.11 5.61 9.58 3.59 55.58333333 6.26 2.79E-09 -3.284144419 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 667705 667705 'Gm8773' mRNA 1 1 1 0.06 0.06 0.06 0.26 0.37 0.11 0.06 0.246666667 5 7 2 1 4.666666667 0.202753496 2.212631127 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66771 66771 'Gid4' mRNA 1566 1571 830 19.12 18.87 10.75 8.05 9.09 9.35 16.24666667 8.83 759 837 854 1322.333333 816.6666667 0.017541689 -0.691680163 GO:0000151///ubiquitin ligase complex GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 66772 66772 'Asb17' mRNA 0 1 0 0 0.06 0 0 0 0.11 0.02 0.036666667 0 0 2 0.333333333 0.666666667 0.863090843 0.890650273 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 66773 66773 'Gm17019' mRNA 0.98 3 4.09 0.06 0.17 0.21 0.09 0.09 0.18 0.146666667 0.12 2.1 2 3.52 2.69 2.54 0.996220413 -0.029646621 667742 667742 'Piezo2' mRNA 6 17 10 0.03 0.08 0.05 0.14 0.16 0.17 0.053333333 0.156666667 36 38 41 11 38.33333333 0.001097942 1.794294351 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005261///cation channel activity+++GO:0005515///protein binding+++GO:0008381///mechanosensitive ion channel activity+++GO:0140135///mechanosensitive cation channel activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0009612///response to mechanical stimulus+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050896///response to stimulus+++GO:0050974///detection of mechanical stimulus involved in sensory perception+++GO:0050982///detection of mechanical stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0098655///cation transmembrane transport 66775 66775 'Hacd4' mRNA 359.04 402.6 413.69 16.58 17.1 20.23 45.94 50.57 47.26 17.97 47.92333333 1159.08 1246.51 1160.7 391.7766667 1188.763333 1.45E-49 1.589655434 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0016829///lyase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0019899///enzyme binding+++GO:0102158///very-long-chain 3-hydroxyacyl-CoA dehydratase activity+++GO:0102343///3-hydroxy-arachidoyl-CoA dehydratase activity+++GO:0102344///3-hydroxy-behenoyl-CoA dehydratase activity+++GO:0102345///3-hydroxy-lignoceroyl-CoA dehydratase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0042761///very long-chain fatty acid biosynthetic process 667772 667772 'Myh15' mRNA 11 4 24 0.09 0.03 0.2 0.03 0.01 0.02 0.106666667 0.02 4 1 3 13 2.666666667 0.033636308 -2.33536654 GO:0005829///cytosol+++GO:0016459///myosin complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0002074///extraocular skeletal muscle development+++GO:0008150///biological_process 667803 667803 'H2-T-ps' mRNA 966.57 939.9 868.36 45.44 43.62 43.31 49.02 47.48 48.48 44.12333333 48.32666667 1197.1 1130.96 1145.04 924.9433333 1157.7 2.97E-04 0.313409446 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis 667823 667823 'Trim5' mRNA 162.68 150.88 121.27 2.83 2.62 2.1 2.4 3.6 2.97 2.516666667 2.99 163.86 196 170.81 144.9433333 176.89 0.220781497 0.28283553 05170///Human immunodeficiency virus 1 infection GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990462///omegasome "GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000209///protein polyubiquitination+++GO:0002218///activation of innate immune response+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0070534///protein K63-linked ubiquitination+++GO:1902187///negative regulation of viral release from host cell" 66784 66784 'Fam187a' mRNA 8 4 3 0.3 0.15 0.12 0.07 0.03 0 0.19 0.033333333 2 1 0 5 1 0.181951321 -2.33023392 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 66787 66787 'Gskip' mRNA 836 876 837 16.57 17.09 17.59 19.84 19.89 21.42 17.08333333 20.38333333 1152 1128 1204 849.6666667 1161.333333 8.98E-07 0.439111343 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0019207///kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051018///protein kinase A binding GO:0006469///negative regulation of protein kinase activity+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0030111///regulation of Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway 66789 66789 'Alg14' mRNA 1012 1018 1090 27.69 27.43 31.66 31.42 31.75 28.37 28.92666667 30.51333333 1320 1301 1153 1040 1258 0.010744537 0.260101632 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043541///UDP-N-acetylglucosamine transferase complex GO:0006488///dolichol-linked oligosaccharide biosynthetic process 66790 66790 'Grtp1' mRNA 554 642 488 23.52 27.37 22.57 12.2 12.52 13.36 24.48666667 12.69333333 315 322 337 561.3333333 324.6666667 7.42E-10 -0.797119029 GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 66793 66793 'Efcab1' mRNA 544 549 517 28.91 28.49 28.63 5.66 3.62 4.02 28.67666667 4.433333333 121 76 83 536.6666667 93.33333333 1.40E-51 -2.537815493 GO:0005930///axoneme+++GO:0097729///9+2 motile cilium GO:0005509///calcium ion binding+++GO:0045504///dynein heavy chain binding+++GO:0046872///metal ion binding+++GO:0048487///beta-tubulin binding+++GO:0120152///calcium-dependent outer dynein arm binding "GO:0060285///cilium-dependent cell motility+++GO:0060326///cell chemotaxis+++GO:1901317///regulation of flagellated sperm motility+++GO:2000578///negative regulation of ATP-dependent microtubule motor activity, minus-end-directed" 66795 66795 'Atg10' mRNA 300 295 290 10.99 10.58 11.19 7.37 6.66 6.49 10.92 6.84 233 205 197 295 211.6666667 0.002574107 -0.491904296 04136///Autophagy - other+++04140///Autophagy - animal GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019777///Atg12 transferase activity+++GO:0019787///ubiquitin-like protein transferase activity+++GO:0061651///Atg12 conjugating enzyme activity GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0006983///ER overload response+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0031401///positive regulation of protein modification process+++GO:0032446///protein modification by small protein conjugation 667962 667962 'Zfp966' mRNA 1.21 1.44 2.03 0.04 0.05 0.07 0.03 0 0.05 0.053333333 0.026666667 1.1 0 3.91 1.56 1.67 0.998591786 -0.029253043 GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II 66797 66797 'Cntnap2' mRNA 817.84 752.73 655.65 11.89 10.64 9.94 3.67 3.51 3.71 10.82333333 3.63 266.18 231.24 263.69 742.0733333 253.7033333 4.50E-37 -1.558626377 04514///Cell adhesion molecules GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030673///axolemma+++GO:0033010///paranodal junction+++GO:0033270///paranode region of axon+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0044224///juxtaparanode region of axon+++GO:0044309///neuron spine+++GO:0044853///plasma membrane raft+++GO:0045202///synapse+++GO:0048787///presynaptic active zone membrane+++GO:0060076///excitatory synapse+++GO:0097060///synaptic membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0150048///cerebellar granule cell to Purkinje cell synapse GO:0002020///protease binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030165///PDZ domain binding+++GO:0044325///ion channel binding "GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0002021///response to dietary excess+++GO:0006954///inflammatory response+++GO:0007005///mitochondrion organization+++GO:0007155///cell adhesion+++GO:0007268///chemical synaptic transmission+++GO:0007409///axonogenesis+++GO:0007612///learning+++GO:0007622///rhythmic behavior+++GO:0007625///grooming behavior+++GO:0007626///locomotory behavior+++GO:0008038///neuron recognition+++GO:0008283///cell proliferation+++GO:0008306///associative learning+++GO:0009408///response to heat+++GO:0009410///response to xenobiotic stimulus+++GO:0009612///response to mechanical stimulus+++GO:0009642///response to light intensity+++GO:0009725///response to hormone+++GO:0010033///response to organic substance+++GO:0010467///gene expression+++GO:0014009///glial cell proliferation+++GO:0019226///transmission of nerve impulse+++GO:0019228///neuronal action potential+++GO:0021549///cerebellum development+++GO:0021692///cerebellar Purkinje cell layer morphogenesis+++GO:0021756///striatum development+++GO:0021761///limbic system development+++GO:0021794///thalamus development+++GO:0021987///cerebral cortex development+++GO:0022010///central nervous system myelination+++GO:0030534///adult behavior+++GO:0031175///neuron projection development+++GO:0031929///TOR signaling+++GO:0032229///negative regulation of synaptic transmission, GABAergic+++GO:0034613///cellular protein localization+++GO:0035176///social behavior+++GO:0035264///multicellular organism growth+++GO:0035556///intracellular signal transduction+++GO:0042297///vocal learning+++GO:0042552///myelination+++GO:0042745///circadian sleep/wake cycle+++GO:0043491///protein kinase B signaling+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0045444///fat cell differentiation+++GO:0045475///locomotor rhythm+++GO:0048265///response to pain+++GO:0048266///behavioral response to pain+++GO:0048812///neuron projection morphogenesis+++GO:0050884///neuromuscular process controlling posture+++GO:0050905///neuromuscular process+++GO:0060079///excitatory postsynaptic potential+++GO:0060996///dendritic spine development+++GO:0061351///neural precursor cell proliferation+++GO:0061744///motor behavior+++GO:0070371///ERK1 and ERK2 cascade+++GO:0071109///superior temporal gyrus development+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0071625///vocalization behavior+++GO:0090659///walking behavior+++GO:0097061///dendritic spine organization+++GO:0097062///dendritic spine maintenance+++GO:0097106///postsynaptic density organization+++GO:0097396///response to interleukin-17+++GO:0098529///neuromuscular junction development, skeletal muscle fiber+++GO:0098976///excitatory chemical synaptic transmission+++GO:0098977///inhibitory chemical synaptic transmission+++GO:0099558///maintenance of synapse structure+++GO:0099610///action potential initiation+++GO:0140059///dendrite arborization+++GO:1901558///response to metformin+++GO:1903598///positive regulation of gap junction assembly+++GO:1904456///negative regulation of neuronal action potential+++GO:1904457///positive regulation of neuronal action potential+++GO:1904861///excitatory synapse assembly+++GO:1904862///inhibitory synapse assembly+++GO:1905962///glutamatergic neuron differentiation+++GO:1990403///embryonic brain development+++GO:1990834///response to odorant" 667977 667977 'Gm8909' mRNA 247.96 249.86 161.44 10.47 9.7 6.91 16.04 16.37 18.6 9.026666667 17.00333333 524.95 501.94 554.93 219.7533333 527.2733333 1.48E-16 1.260687928 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0042605///peptide antigen binding "GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent+++GO:0006955///immune response" 66799 66799 'Ube2w' mRNA 1232 1270.62 1332.86 22.21 22.43 25.46 25.04 25.04 25.02 23.36666667 25.03333333 1614.69 1573.28 1568.34 1278.493333 1585.436667 7.06E-04 0.296598427 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006513///protein monoubiquitination+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0071218///cellular response to misfolded protein 66801 66801 'Prkrip1' mRNA 219 255 265 7.72 8.86 9.9 10.06 10.18 9.38 8.826666667 9.873333333 328 324 296 246.3333333 316 0.043527268 0.344834643 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus GO:0003725///double-stranded RNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0003014///renal system process+++GO:0006397///mRNA processing+++GO:0006469///negative regulation of protein kinase activity+++GO:0008380///RNA splicing+++GO:0042326///negative regulation of phosphorylation 668039 668039 'Gm14434' mRNA 65.22 93.32 63.36 0.55 0.46 0.68 0.45 0.02 0.44 0.563333333 0.303333333 71.23 3.07 53.81 73.96666667 42.70333333 0.540032602 -0.819755555 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 66805 66805 'Tspan1' mRNA 49 42 54 2.11 1.77 2.29 14.4 12.47 13.4 2.056666667 13.42333333 400 348 370 48.33333333 372.6666667 6.16E-49 2.931783592 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0050821///protein stabilization 66808 66808 '9030624G23Rik' mRNA 77.84 71.36 67.33 1.14 1.07 1.13 0.59 0.59 0.59 1.113333333 0.59 42.14 44.45 42.29 72.17666667 42.96 0.024241125 -0.758391011 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 66809 66809 'Krt20' mRNA 191 184 165 5.6 5.31 5.13 0.28 0.47 0.9 5.346666667 0.55 11 18 34 180 21 2.79E-22 -3.106489492 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005882///intermediate filament GO:0005198///structural molecule activity+++GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0009267///cellular response to starvation+++GO:0045109///intermediate filament organization+++GO:0050708///regulation of protein secretion 66810 66810 'Rbm22' mRNA 713 722 543 19.44 19.4 15.71 18.15 17.1 16.84 18.18333333 17.36333333 765 704 687 659.3333333 718.6666667 0.38238522 0.117073994 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0017070///U6 snRNA binding+++GO:0036002///pre-mRNA binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding "GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0033120///positive regulation of RNA splicing+++GO:0035690///cellular response to drug+++GO:0042307///positive regulation of protein import into nucleus+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0046827///positive regulation of protein export from nucleus+++GO:0071466///cellular response to xenobiotic stimulus" 668101 668101 'Sirpb1b' mRNA 6.95 11.46 0 0.27 0.45 0 5.7 5.98 4.93 0.24 5.536666667 164.85 170.19 139.32 6.136666667 158.12 6.07E-09 4.8159601 04380///Osteoclast differentiation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation 668106 668106 'Gm8978' mRNA 0 2 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component "GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds" GO:0006629///lipid metabolic process+++GO:0008150///biological_process+++GO:0016042///lipid catabolic process 668110 668110 'Syce1l' mRNA 2 0 2 0.18 0 0.19 0 0 0 0.123333333 0 0 0 0 1.333333333 0 0.468848267 -2.893033412 GO:0000795///synaptonemal complex+++GO:0045111///intermediate filament cytoskeleton GO:0003674///molecular_function GO:0007130///synaptonemal complex assembly+++GO:0008150///biological_process+++GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization 66812 66812 'Ppcdc' mRNA 6550.94 6671.66 6269.87 209.39 210.28 213.58 120.97 113.29 121.5 211.0833333 118.5866667 4240.46 3853.32 4108.01 6497.49 4067.263333 1.28E-36 -0.687735349 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0071513///phosphopantothenoylcysteine decarboxylase complex GO:0003824///catalytic activity+++GO:0004633///phosphopantothenoylcysteine decarboxylase activity+++GO:0010181///FMN binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0042802///identical protein binding GO:0015937///coenzyme A biosynthetic process 66813 66813 'Bcl2l14' mRNA 236 225 255 6.09 5.72 6.98 4.69 5.08 4.12 6.263333333 4.63 209 221 178 238.6666667 202.6666667 0.216858855 -0.250453364 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043229///intracellular organelle GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0006915///apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:2001236///regulation of extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 66815 66815 'Mcub' mRNA 120 124 118 5.61 5.9 5.97 14.19 14.95 15.09 5.826666667 14.74333333 339 352 352 120.6666667 347.6666667 2.88E-20 1.515798399 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0034704///calcium channel complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990246///uniplex complex GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0019855///calcium channel inhibitor activity GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051560///mitochondrial calcium ion homeostasis 668158 668158 'Ccdc85c' mRNA 438.71 372.76 397.61 4.8 3.75 4.35 1.32 1.47 1.87 4.3 1.553333333 132.86 152.09 189.47 403.0266667 158.14 3.15E-15 -1.362582653 GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0043296///apical junction complex GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0021987///cerebral cortex development 66816 66816 'Thap2' mRNA 567 647 575 6.09 6.83 6.55 4.25 3.5 3.92 6.49 3.89 456 367 407 596.3333333 410 8.32E-06 -0.552993735 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 668166 668166 'Zxdb' mRNA 175 164 124 1.66 1.53 1.24 1.31 1.33 1.46 1.476666667 1.366666667 159 158 172 154.3333333 163 0.798005004 0.072617487 GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0046872///metal ion binding+++GO:0070742///C2H2 zinc finger domain binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 66817 66817 'Tmem170' mRNA 1548 1496 1472 22.28 21.37 22.28 12.98 12.72 12.97 21.97666667 12.89 1044 997 1009 1505.333333 1016.666667 4.06E-13 -0.578382965 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006998///nuclear envelope organization+++GO:0051292///nuclear pore complex assembly+++GO:0071786///endoplasmic reticulum tubular network organization 668173 668173 'Pex10' mRNA 389 415 349 13.77 14.48 13.11 8.07 7.64 7.45 13.78666667 7.72 262 242 234 384.3333333 246 5.00E-06 -0.653580697 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding GO:0007031///peroxisome organization+++GO:0016558///protein import into peroxisome matrix 668178 668178 'Mettl7a3' mRNA 10.35 7.22 11.46 0.38 0.29 0.43 0.25 0.23 0.35 0.366666667 0.276666667 7.68 7.64 11.46 9.676666667 8.926666667 0.863090843 -0.181092291 GO:0005811///lipid droplet+++GO:0016021///integral component of membrane GO:0008168///methyltransferase activity GO:0032259///methylation 66818 66818 'Smim7' mRNA 2836 2969 2996 55.03 56.7 61.67 46.18 46.42 45.24 57.8 45.94666667 2738 2688 2597 2933.666667 2674.333333 0.055165156 -0.146924826 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 668205 668205 'Gm9045' mRNA 0 2.26 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.753333333 0 0.750387006 -1.824848553 GO:0000974///Prp19 complex+++GO:0005681///spliceosomal complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" "GO:0000398///mRNA splicing, via spliceosome+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 668208 668208 'Gm13288' mRNA 3.23 14.61 9.39 0.06 0.28 0.19 0.13 0.09 0.41 0.176666667 0.21 7.59 5.12 23.88 9.076666667 12.19666667 0.72754773 0.420540748 GO:0005575///cellular_component+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005125///cytokine activity+++GO:0005132///type I interferon receptor binding GO:0002250///adaptive immune response+++GO:0002286///T cell activation involved in immune response+++GO:0002323///natural killer cell activation involved in immune response+++GO:0006959///humoral immune response+++GO:0008150///biological_process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0042100///B cell proliferation+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus 66821 66821 'Bcs1l' mRNA 301 275 219 9.46 8.48 7.21 8.23 7.66 9.09 8.383333333 8.326666667 302 278 324 265 301.3333333 0.341118175 0.177924237 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0007005///mitochondrion organization+++GO:0032979///protein insertion into mitochondrial inner membrane from matrix side+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0034551///mitochondrial respiratory chain complex III assembly 668210 668210 'Atp6v1fnb' mRNA 0 1.01 2.02 0 0.11 0.24 0 0 0.1 0.116666667 0.033333333 0 0 1 1.01 0.333333333 0.718026697 -1.523976857 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 668212 668212 'Efr3b' mRNA 281.1 246.14 300.49 2.27 1.96 2.58 1.97 1.85 1.64 2.27 1.82 280.39 256.7 227 275.91 254.6966667 0.529175373 -0.132892321 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0003674///molecular_function GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 668218 668218 'Bin2' mRNA 99 97 102 2.93 2.75 3.11 20.06 18.34 19.5 2.93 19.3 793 714 747 99.33333333 751.3333333 3.03E-95 2.906172894 GO:0001891///phagocytic cup+++GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0005543///phospholipid binding "GO:0006911///phagocytosis, engulfment+++GO:0060326///cell chemotaxis+++GO:0071800///podosome assembly+++GO:0097320///plasma membrane tubulation" 66822 66822 'Fbxo25' mRNA 572.46 653.42 615 15.04 16.98 17.06 13.22 14.75 14.83 16.36 14.26666667 572.07 624 630 613.6266667 608.69 0.881854462 -0.022236666 04068///FoxO signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0003779///actin binding+++GO:0005515///protein binding GO:0016567///protein ubiquitination 668225 668225 'Fignl2' mRNA 2 4 2 0.02 0.04 0.03 0.06 0.06 0.15 0.03 0.09 7 6 13 2.666666667 8.666666667 0.151403033 1.696622629 GO:0005634///nucleus GO:0005524///ATP binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016887///ATPase activity GO:0031122///cytoplasmic microtubule organization+++GO:0051013///microtubule severing 66824 66824 'Pycard' mRNA 302 303 306 8 7.9 8.6 36.35 35.46 38.88 8.166666667 36.89666667 1578 1503 1634 303.6666667 1571.666667 3.96E-132 2.359494808 04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05133///Pertussis+++05134///Legionellosis+++05135///Yersinia infection+++05164///Influenza A+++05417///Lipid and atherosclerosis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0008385///IkappaB kinase complex+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0061702///inflammasome complex+++GO:0072558///NLRP1 inflammasome complex+++GO:0072559///NLRP3 inflammasome complex+++GO:0097169///AIM2 inflammasome complex GO:0002020///protease binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0005138///interleukin-6 receptor binding+++GO:0005515///protein binding+++GO:0005523///tropomyosin binding+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0017024///myosin I binding+++GO:0019899///enzyme binding+++GO:0032090///Pyrin domain binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding+++GO:0046983///protein dimerization activity+++GO:0070700///BMP receptor binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process GO:0001773///myeloid dendritic cell activation+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0002376///immune system process+++GO:0002588///positive regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0002821///positive regulation of adaptive immune response+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006954///inflammatory response+++GO:0009617///response to bacterium+++GO:0010506///regulation of autophagy+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031647///regulation of protein stability+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032611///interleukin-1 beta production+++GO:0032688///negative regulation of interferon-beta production+++GO:0032722///positive regulation of chemokine production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043087///regulation of GTPase activity+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044351///macropinocytosis+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0050727///regulation of inflammatory response+++GO:0050766///positive regulation of phagocytosis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050870///positive regulation of T cell activation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051260///protein homooligomerization+++GO:0051607///defense response to virus+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:2000406///positive regulation of T cell migration+++GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001242///regulation of intrinsic apoptotic signaling pathway 66825 66825 'Rnf186' mRNA 0 0 1 0 0 0.05 0 0.04 0.09 0.016666667 0.043333333 0 1 2 0.333333333 1 0.727544503 1.480842798 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0035519///protein K29-linked ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070534///protein K63-linked ubiquitination+++GO:0070585///protein localization to mitochondrion 66826 66826 'Taz' mRNA 2665.19 2690.39 2678.82 82.45 82.37 88.29 56.57 56.99 54.13 84.37 55.89666667 2078.06 2047.19 1922.12 2678.133333 2015.79 2.48E-09 -0.422466281 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity" GO:0000423///mitophagy+++GO:0003007///heart morphogenesis+++GO:0006644///phospholipid metabolic process+++GO:0006936///muscle contraction+++GO:0007005///mitochondrion organization+++GO:0007007///inner mitochondrial membrane organization+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0030097///hemopoiesis+++GO:0032048///cardiolipin metabolic process+++GO:0032049///cardiolipin biosynthetic process+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0042407///cristae formation+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0048137///spermatocyte division+++GO:0048738///cardiac muscle tissue development+++GO:0060048///cardiac muscle contraction+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900210///positive regulation of cardiolipin metabolic process+++GO:2001171///positive regulation of ATP biosynthetic process 66827 66827 'Ttc1' mRNA 981 1042 1037 39.65 41.54 44.47 41.87 42.77 41.29 41.88666667 41.97666667 1190 1186 1135 1020 1170.333333 0.053925786 0.185515895 GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 66830 66830 'Nacc1' mRNA 612 665 484 7.68 8.16 6.44 9.42 8.93 8.71 7.426666667 9.02 868 801 768 587 812.3333333 5.93E-05 0.461559698 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated" 668303 668303 'Kif26a' mRNA 48 39 42 0.37 0.29 0.33 0.32 0.18 0.21 0.33 0.236666667 49 27 30 43 35.33333333 0.55512972 -0.300599257 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity GO:0001560///regulation of cell growth by extracellular stimulus+++GO:0007018///microtubule-based movement+++GO:0009968///negative regulation of signal transduction+++GO:0048484///enteric nervous system development 668310 668310 'Cc2d2b' mRNA 0 4 4 0 0.03 0.03 0.01 0.01 0.01 0.02 0.01 2 2 2 2.666666667 2 0.858069997 -0.438888511 GO:0035869///ciliary transition zone GO:0003674///molecular_function GO:1904491///protein localization to ciliary transition zone+++GO:1905515///non-motile cilium assembly 66832 66832 'Rsph3a' mRNA 861.62 794.69 850.49 25.08 22.79 26.27 20.79 18.03 18.5 24.71333333 19.10666667 821.05 694.9 706.95 835.6 740.9666667 0.106211944 -0.188431466 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 66834 66834 'Acot13' mRNA 1376 1400 1323 144.5 146.04 147.45 126.63 133.93 134.22 145.9966667 131.5933333 1378 1418 1409 1366.333333 1401.666667 0.817847257 0.025862009 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0051289///protein homotetramerization+++GO:0120163///negative regulation of cold-induced thermogenesis 66836 66836 'Tmem223' mRNA 1298 1342 1274 120.96 124.07 126 117.24 132.16 117.84 123.6766667 122.4133333 1439 1579 1396 1304.666667 1471.333333 0.082477169 0.162642284 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007399///nervous system development 668382 668382 'Pabpc1l2b' mRNA 27.95 33.15 12.96 0.59 0.68 0.29 0.19 0.26 0.59 0.52 0.346666667 10.17 13.71 31.38 24.68666667 18.42 0.607260342 -0.406226978 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66839 66839 'Dele1' mRNA 1755 1863 1574 40.81 42.66 38.83 24.65 23.9 24.42 40.76666667 24.32333333 1219 1154 1169 1730.666667 1180.666667 1.67E-13 -0.561293849 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071902///positive regulation of protein serine/threonine kinase activity 66840 66840 'Wdr45b' mRNA 1067 1134 1022 25.51 26.69 25.92 30.18 26.03 27.83 26.04 28.01333333 1452 1223 1296 1074.333333 1323.666667 0.001204941 0.289018709 GO:0000407///phagophore assembly site+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0034045///phagophore assembly site membrane "GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0034497///protein localization to phagophore assembly site+++GO:0044804///autophagy of nucleus 66841 66841 'Etfdh' mRNA 1006 1097 1078 24.78 26.61 28.16 27.01 27.55 29.53 26.51666667 28.03 1261 1256 1335 1060.333333 1284 0.004787048 0.263569863 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0017133///mitochondrial electron transfer flavoprotein complex+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane "GO:0004174///electron-transferring-flavoprotein dehydrogenase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0043783///oxidoreductase activity, oxidizing metal ions with flavin as acceptor+++GO:0046872///metal ion binding+++GO:0048038///quinone binding+++GO:0048039///ubiquinone binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006979///response to oxidative stress+++GO:0022900///electron transport chain+++GO:0022904///respiratory electron transport chain+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase 668433 668433 '4930544D05Rik' mRNA 2 2 3 0.16 0.16 0.25 0 0 0.07 0.19 0.023333333 0 0 1 2.333333333 0.333333333 0.295953501 -2.72548198 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66844 66844 'Ormdl2' mRNA 1306.85 1360.46 1289.71 48.24 49.52 50.55 53.27 48.35 46.67 49.43666667 49.43 1657.61 1467.17 1402.93 1319.006667 1509.236667 0.043176639 0.181740732 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035339///SPOTS complex GO:0003674///molecular_function GO:0006672///ceramide metabolic process+++GO:0090155///negative regulation of sphingolipid biosynthetic process+++GO:0090156///cellular sphingolipid homeostasis+++GO:1900060///negative regulation of ceramide biosynthetic process 66845 66845 'Mrpl33' mRNA 582 576 629 111.1 110.23 127.51 137.57 152.69 156.61 116.28 148.9566667 818 880 895 595.6666667 864.3333333 2.75E-06 0.523681001 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 66847 66847 'Hint3' mRNA 1809.59 1773.04 1664.96 26.54 25.08 26.41 22.76 28.72 27.62 26.01 26.36666667 1248.15 1257.01 1225.84 1749.196667 1243.666667 1.68E-11 -0.502832999 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043530///adenosine 5'-monophosphoramidase activity 66848 66848 'Fuca2' mRNA 1336 1528 1432 30.54 34.22 34.58 64.81 65.46 63.31 33.11333333 64.52666667 3137 3161 2998 1432 3098.666667 1.53E-49 1.101653141 00511///Other glycan degradation+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome "GO:0004560///alpha-L-fucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0006004///fucose metabolic process+++GO:0008152///metabolic process+++GO:0009617///response to bacterium+++GO:0016139///glycoside catabolic process+++GO:2000535///regulation of entry of bacterium into host cell 66849 66849 'Ppp1r2' mRNA 3197 3191 3268 42.32 41.55 45.89 44.26 41.44 43.92 43.25333333 43.20666667 3849 3520 3699 3218.666667 3689.333333 0.009157949 0.183023647 GO:0005737///cytoplasm+++GO:0030426///growth cone+++GO:0043197///dendritic spine GO:0004864///protein phosphatase inhibitor activity+++GO:0019904///protein domain specific binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0009966///regulation of signal transduction+++GO:0032091///negative regulation of protein binding+++GO:0043666///regulation of phosphoprotein phosphatase activity 668501 668501 'Zfp507' mRNA 512 542 453 4.05 4.21 3.82 2.89 2.47 2.8 4.026666667 2.72 421 350 397 502.3333333 389.3333333 0.003639571 -0.377936479 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 668525 668525 'Gm9222' mRNA 975.46 938.89 814.23 19.64 15.71 16.86 10.21 10.09 9.58 17.40333333 9.96 731.54 620.44 642.61 909.5266667 664.8633333 6.24E-06 -0.462768372 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66853 66853 'Pnpla2' mRNA 2425 2450 2407 51.05 50.77 53.75 47.58 50.77 48.56 51.85666667 48.97 2599 2709 2569 2427.333333 2625.666667 0.197284964 0.101506916 00561///Glycerolipid metabolism+++04714///Thermogenesis+++04923///Regulation of lipolysis in adipocytes GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004806///triglyceride lipase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0050253///retinyl-palmitate esterase activity GO:0006629///lipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0019915///lipid storage+++GO:0034389///lipid droplet organization+++GO:0042572///retinol metabolic process+++GO:0044242///cellular lipid catabolic process+++GO:0055088///lipid homeostasis 66854 66854 'Trim35' mRNA 2094 2000 2085 30.82 28.96 32.55 37.89 38.16 39.11 30.77666667 38.38666667 2963 2915 2962 2059.666667 2946.666667 8.94E-13 0.503565497 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0043065///positive regulation of apoptotic process+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045930///negative regulation of mitotic cell cycle+++GO:1902187///negative regulation of viral release from host cell 668548 668548 'Gm9234' mRNA 16.84 14.87 32.84 1.57 1.38 3.26 2.42 2.94 2.88 2.07 2.746666667 29.55 35.01 33.97 21.51666667 32.84333333 0.294590179 0.61863406 66855 66855 'Tcf25' mRNA 10468 10669 10617 153.41 154.45 168.45 115.74 113.23 112.76 158.77 113.91 8232 7842 7771 10584.66667 7948.333333 1.43E-14 -0.426466723 GO:0005634///nucleus+++GO:1990112///RQC complex GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity GO:0000122///negative regulation of transcription by RNA polymerase II 668553 668553 'Gm9237' mRNA 60.69 62.1 59.98 5.13 4.91 4.42 3.37 4.58 2.97 4.82 3.64 36.85 53.49 43.08 60.92333333 44.47333333 0.232336384 -0.464179909 66857 66857 'Plbd1' mRNA 174 153 145 5.03 4.36 4.45 26.1 24.05 23.1 4.613333333 24.41666667 1036 932 887 157.3333333 951.6666667 7.68E-96 2.585218482 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome GO:0004620///phospholipase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process 668588 668588 'Gm9257' mRNA 5.7 3.9 5.74 0.18 0.12 0.19 0.14 0.06 0.05 0.163333333 0.083333333 5.17 2.24 1.86 5.113333333 3.09 0.669955001 -0.728324897 66859 66859 'Slc16a9' mRNA 231 213 130 3.91 3.57 2.1 1.48 1.41 1.57 3.193333333 1.486666667 105 104 112 191.3333333 107 4.12E-04 -0.840037004 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0046415///urate metabolic process+++GO:0055085///transmembrane transport 66860 66860 'Tanc1' mRNA 2345 2454 2205 16.83 17.32 16.81 7.84 7.61 8.32 16.98666667 7.923333333 1289 1233 1317 2334.666667 1279.666667 2.37E-36 -0.878069316 "GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0003674///molecular_function GO:0007520///myoblast fusion+++GO:0008542///visual learning+++GO:0097062///dendritic spine maintenance+++GO:0099175///regulation of postsynapse organization 66861 66861 'Dnajc10' mRNA 2786 2875 2980 37.07 37.63 42.06 44.67 44.77 42.52 38.92 43.98666667 3864 3783 3562 2880.333333 3736.333333 7.40E-07 0.361350409 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034663///endoplasmic reticulum chaperone complex "GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015036///disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0030544///Hsp70 protein binding+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding+++GO:0051787///misfolded protein binding" GO:0001933///negative regulation of protein phosphorylation+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032781///positive regulation of ATPase activity+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0050790///regulation of catalytic activity+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 668620 668620 'Zfp936' mRNA 1.01 1.01 1.01 0.02 0.02 0.02 0.02 0.02 0.06 0.02 0.033333333 1 1.01 4 1.01 2.003333333 0.70219452 0.991009496 05168///Herpes simplex virus 1 infection GO:0005634///nucleus GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0010468///regulation of gene expression" 66863 66863 'Lztr1' mRNA 2110.77 2081.61 1924.15 33.75 32.76 32.79 25.69 25.29 24.71 33.1 25.23 1830.87 1748.03 1724.98 2038.843333 1767.96 0.002371402 -0.216790289 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0031267///small GTPase binding GO:0016567///protein ubiquitination+++GO:0046580///negative regulation of Ras protein signal transduction 66864 66864 'Clec14a' mRNA 282 240 227 3.33 2.79 2.85 5.42 5.9 5.78 2.99 5.7 528 561 545 249.6666667 544.6666667 6.18E-17 1.115995567 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0030246///carbohydrate binding+++GO:0050840///extracellular matrix binding+++GO:1990430///extracellular matrix protein binding GO:0001946///lymphangiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0016477///cell migration+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0036325///vascular endothelial growth factor receptor-3 signaling pathway 66865 66865 'Pmpca' mRNA 1581.03 1754.78 1649.91 30.47 32.64 33.17 32.65 31.41 31.72 32.09333333 31.92666667 1984.47 1878.4 1868.45 1661.906667 1910.44 0.018797412 0.18885944 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006627///protein processing involved in protein targeting to mitochondrion 66866 66866 'Nhlrc2' mRNA 3617 3822 3269 30.29 31.29 30.16 11.72 10.77 10.85 30.58 11.11333333 1584 1433 1422 3569.333333 1479.666667 1.25E-82 -1.280583075 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 668661 668661 '2410002F23Rik' mRNA 1652.96 1636 1615 44.87 43.74 46.42 40.92 37 37.07 45.01 38.33 1733.96 1512.97 1518.96 1634.653333 1588.63 0.589342593 -0.05517477 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66867 66867 'Hmg20a' mRNA 2326 2508 2347 33.39 35.43 35.75 15.68 14.53 15.65 34.85666667 15.28666667 1258 1139 1216 2393.666667 1204.333333 5.06E-43 -1.003317207 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0010468///regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0045665///negative regulation of neuron differentiation 66868 66868 'Mfsd1' mRNA 1764 1751 1650 32.55 31.8 32.3 67.78 65.38 68.76 32.21666667 67.30666667 4226 3981 4151 1721.666667 4119.333333 1.50E-95 1.247169148 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0042803///protein homodimerization activity GO:0050821///protein stabilization+++GO:0055085///transmembrane transport+++GO:0061462///protein localization to lysosome 66869 66869 'Zfp869' mRNA 1529.43 1472.54 1394.01 25.54 24.04 24.63 15.5 15.52 14.89 24.73666667 15.30333333 1065.27 1043.76 997.3 1465.326667 1035.443333 1.79E-10 -0.512410325 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070895///negative regulation of transposon integration" 66870 66870 'Serbp1' mRNA 3152.22 3083.53 2914.94 25.06 24.09 24.57 27.16 27.11 26.66 24.57333333 26.97666667 3931.05 3835.41 3739.21 3050.23 3835.223333 8.41E-08 0.319348467 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0032183///SUMO binding+++GO:0043022///ribosome binding GO:0030578///PML body organization+++GO:0042981///regulation of apoptotic process 66871 66871 'Cpne8' mRNA 793.23 738.61 711.1 39.57 37.94 39.04 76.96 77.45 81.04 38.85 78.48333333 1562.13 1569.64 1526.82 747.6466667 1552.863333 3.90E-36 1.043728459 GO:0005886///plasma membrane GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0071277///cellular response to calcium ion 668727 668727 'Mrgpra2a' mRNA 2.37 5.6 0 0.11 0.26 0 0 0 0.25 0.123333333 0.083333333 0 0 5.9 2.656666667 1.966666667 0.865040332 -0.453155066 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0043303///mast cell degranulation+++GO:0045576///mast cell activation 66873 66873 'Tril' mRNA 3482 3691 3702 34.62 36.09 39.05 9.42 9.47 9.58 36.58666667 9.49 1091 1071 1074 3625 1078.666667 1.58E-127 -1.76210759 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0046696///lipopolysaccharide receptor complex GO:0001530///lipopolysaccharide binding GO:0002376///immune system process+++GO:0002718///regulation of cytokine production involved in immune response+++GO:0006954///inflammatory response+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response 66874 66874 'Ncbp3' mRNA 752.16 697.51 616.93 6.8 6.24 5.52 5.45 5.49 5.36 6.186666667 5.433333333 709.02 731.97 677.09 688.8666667 706.0266667 0.863090843 0.026915804 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0000339///RNA cap binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0051028///mRNA transport+++GO:0051607///defense response to virus 66875 66875 'Swt1' mRNA 439 485 420 6.49 7.08 6.61 5.01 4.96 5.36 6.726666667 5.11 385 372 396 448 384.3333333 0.090052397 -0.23131519 GO:0005634///nucleus GO:0003674///molecular_function 66877 66877 'Crnkl1' mRNA 541 577 626 9.53 10 11.7 11.4 11.08 10.46 10.41 10.98 745 707 662 581.3333333 704.6666667 0.035947969 0.262228751 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex GO:0003723///RNA binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 66878 66878 'Riok3' mRNA 1423.02 1324.64 1325.61 21.08 19.31 20.83 26.3 23.17 24.12 20.40666667 24.53 2043.14 1758.32 1814.55 1357.756667 1872.003333 2.89E-08 0.450320046 "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030688///preribosome, small subunit precursor" GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0089720///caspase binding GO:0002376///immune system process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030490///maturation of SSU-rRNA+++GO:0031333///negative regulation of protein complex assembly+++GO:0032728///positive regulation of interferon-beta production+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus+++GO:0071359///cellular response to dsRNA+++GO:0098586///cellular response to virus+++GO:1990786///cellular response to dsDNA 66880 66880 'Rsrc1' mRNA 2703.98 2639.77 2590.25 37.18 35.67 38.17 20.32 17.22 18.55 37.00666667 18.69666667 1662.95 1372.33 1506.91 2644.666667 1514.063333 3.57E-27 -0.818509468 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0005515///protein binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006913///nucleocytoplasmic transport+++GO:0008380///RNA splicing+++GO:0046677///response to antibiotic" 66881 66881 'Pcyox1' mRNA 2760 3123 3067 34.68 38.59 40.95 39.1 37.79 36.34 38.07333333 37.74333333 3564 3368 3223 2983.333333 3385 0.038914482 0.168348327 00900///Terpenoid backbone biosynthesis GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034361///very-low-density lipoprotein particle "GO:0001735///prenylcysteine oxidase activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0016491///oxidoreductase activity+++GO:0016670///oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor" GO:0006821///chloride transport+++GO:0030327///prenylated protein catabolic process+++GO:0030328///prenylcysteine catabolic process+++GO:1902476///chloride transmembrane transport 66882 66882 'Bzw1' mRNA 2597 2697 2641 36.36 37.14 39.07 60.15 60.13 59.86 37.52333333 60.04666667 4942 4848 4785 2645 4858.333333 3.69E-46 0.864738581 GO:0005737///cytoplasm 66884 66884 'Appbp2' mRNA 1187 1303 539 27.57 29.8 13.28 13 19.48 18.9 23.55 17.12666667 644 942 906 1009.666667 830.6666667 0.60428608 -0.27076911 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0046907///intracellular transport 66885 66885 'Acadsb' mRNA 2646 2887 2657 43.1 46.26 45.91 35.03 38.65 35.43 45.09 36.37 2475 2667 2424 2730 2522 0.123173839 -0.125000121 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++01212///Fatty acid metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003853///2-methylacyl-CoA dehydrogenase activity+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016937///short-branched-chain-acyl-CoA dehydrogenase activity+++GO:0042802///identical protein binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0102035///isobutyryl-CoA:FAD oxidoreductase activity" GO:0006550///isoleucine catabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0022900///electron transport chain 66887 66887 'Lonp2' mRNA 2056.83 2179.1 2121.44 40 41.87 45.08 32.9 37.25 29.89 42.31666667 33.34666667 1909 1914.3 1636.33 2119.123333 1819.876667 0.0079481 -0.232147043 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix GO:0000166///nucleotide binding+++GO:0002020///protease binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019899///enzyme binding GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006625///protein targeting to peroxisome+++GO:0014070///response to organic cyclic compound+++GO:0016485///protein processing+++GO:0016558///protein import into peroxisome matrix+++GO:0030163///protein catabolic process+++GO:0031998///regulation of fatty acid beta-oxidation 668880 668880 'Stard9' mRNA 604 599 529 2.05 2.01 1.91 2.3 1.96 2.11 1.99 2.123333333 777 648 691 577.3333333 705.3333333 0.014600464 0.277705641 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity" GO:0007018///microtubule-based movement+++GO:0051225///spindle assembly 66889 66889 'Rnf128' mRNA 2338 2439 2373 48.47 49.67 52.11 23.64 22.17 22.83 50.08333333 22.88 1344 1230 1255 2383.333333 1276.333333 2.38E-36 -0.913962871 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001818///negative regulation of cytokine production+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability 668894 668894 'Vinac1' mRNA 838.37 898.6 769.76 4.72 5 4.64 0.65 0.59 0.53 4.786666667 0.59 133.3 126.26 106.29 835.5766667 121.95 3.63E-97 -2.788950451 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0016342///catenin complex GO:0008013///beta-catenin binding+++GO:0051015///actin filament binding GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0098609///cell-cell adhesion 66890 66890 'Lman2' mRNA 4282 4351 4694 53.36 53.33 62.05 60.76 61.57 57.41 56.24666667 59.91333333 5612 5556 5136 4442.333333 5434.666667 3.36E-04 0.275877175 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005615///extracellular space+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0050766///positive regulation of phagocytosis" 66892 66892 'Eif4e3' mRNA 353 345 344 7.28 7 7.67 9.68 10.24 9.81 7.316666667 9.91 516 532 506 347.3333333 518 6.16E-06 0.564898221 GO:0005845///mRNA cap binding complex+++GO:0016281///eukaryotic translation initiation factor 4F complex GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006417///regulation of translation 668923 668923 'Zfp442' mRNA 216.34 237.41 242.64 1.5 1.61 1.73 1.31 1.24 1.22 1.613333333 1.256666667 223.08 202.36 204.3 232.13 209.9133333 0.44205345 -0.158210641 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 668929 668929 'Rad21l' mRNA 1 4 1 0.02 0.08 0.02 0.02 0 0 0.04 0.006666667 1 0 0 2 0.333333333 0.389792055 -2.471653335 GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0008278///cohesin complex+++GO:0030893///meiotic cohesin complex+++GO:0034990///nuclear mitotic cohesin complex+++GO:0034991///nuclear meiotic cohesin complex GO:0003682///chromatin binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006302///double-strand break repair+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007129///synapsis+++GO:0007130///synaptonemal complex assembly+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0051321///meiotic cell cycle+++GO:0070197///meiotic attachment of telomere to nuclear envelope+++GO:0072520///seminiferous tubule development+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange 66894 66894 'Wwp2' mRNA 2153 2249 2406 25.64 26.43 30.43 19.23 19.77 18.56 27.5 19.18666667 1860 1856 1731 2269.333333 1815.666667 1.06E-04 -0.336566368 04120///Ubiquitin mediated proteolysis GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006858///extracellular transport+++GO:0010629///negative regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0032410///negative regulation of transporter activity+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051224///negative regulation of protein transport+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:1901016///regulation of potassium ion transmembrane transporter activity" 668940 668940 'Myh7b' mRNA 26 34 40 0.2 0.27 0.36 0.05 0.05 0.07 0.276666667 0.056666667 7 6 10 33.33333333 7.666666667 3.52E-04 -2.138941451 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0032982///myosin filament+++GO:0042641///actomyosin+++GO:0043209///myelin sheath+++GO:0097512///cardiac myofibril+++GO:0097513///myosin II filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0019228///neuronal action potential+++GO:0030048///actin filament-based movement+++GO:0031032///actomyosin structure organization+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0070584///mitochondrion morphogenesis+++GO:0071625///vocalization behavior+++GO:1905289///regulation of CAMKK-AMPK signaling cascade 66895 66895 'Pxdc1' mRNA 880 820 715 26.92 24.69 23.16 13.76 13.82 13.55 24.92333333 13.71 516 506 492 805 504.6666667 1.19E-10 -0.682715003 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0035091///phosphatidylinositol binding GO:0008150///biological_process 66897 66897 'Naa16' mRNA 342 332 382 4.77 4.56 5.64 4.38 4.32 4.59 4.99 4.43 362 347 368 352 359 0.948302371 0.013022605 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031415///NatA complex GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0043022///ribosome binding GO:0006474///N-terminal protein amino acid acetylation+++GO:0017196///N-terminal peptidyl-methionine acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization 66898 66898 'Baiap2l1' mRNA 512 494 447 8.61 8.18 7.98 5.79 6.27 6.05 8.256666667 6.036666667 396 419 401 484.3333333 405.3333333 0.04143246 -0.266409585 05130///Pathogenic Escherichia coli infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton GO:0003779///actin binding+++GO:0070064///proline-rich region binding GO:0007009///plasma membrane organization+++GO:0009617///response to bacterium+++GO:0030833///regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0051017///actin filament bundle assembly+++GO:0051764///actin crosslink formation+++GO:2000251///positive regulation of actin cytoskeleton reorganization 66899 66899 'Fip1l1' mRNA 1552.16 1636.72 1622.63 18.88 19.53 20.75 19.57 18.78 19.18 19.72 19.17666667 1621.74 1518.67 1549.35 1603.836667 1563.253333 0.621710164 -0.050302823 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0098789///pre-mRNA cleavage required for polyadenylation 66901 66901 'Proz' mRNA 10.25 7.15 14.48 0.16 0.11 0.24 0.1 0.06 0.17 0.17 0.11 7.12 4.09 9.04 10.62666667 6.75 0.528722903 -0.65890006 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0007599///hemostasis 66902 66902 'Mtap' mRNA 640 610 607 13.91 13.05 14 18.96 18.33 17.39 13.65333333 18.22666667 1003 947 891 619 947 1.03E-09 0.601002625 00270///Cysteine and methionine metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0017061///S-methyl-5-thioadenosine phosphorylase activity" GO:0006166///purine ribonucleoside salvage+++GO:0009116///nucleoside metabolic process+++GO:0019509///L-methionine salvage from methylthioadenosine+++GO:0032259///methylation 66904 66904 'Pccb' mRNA 1129 1164 1159 27.49 27.96 29.95 23.81 26.74 24.66 28.46666667 25.07 1123 1233 1126 1150.666667 1160.666667 0.998591786 6.61E-04 "00280///Valine, leucine and isoleucine degradation+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0009317///acetyl-CoA carboxylase complex GO:0000166///nucleotide binding+++GO:0003989///acetyl-CoA carboxylase activity+++GO:0004658///propionyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006633///fatty acid biosynthetic process 66905 66905 'Plin3' mRNA 5116 5414 5177.98 133.83 139.5 143.69 118.37 116.83 115.49 139.0066667 116.8966667 5203 5014 4914 5235.993333 5043.666667 0.33671043 -0.066261523 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0005515///protein binding GO:0010890///positive regulation of sequestering of triglyceride+++GO:0019915///lipid storage 66910 66910 'Tmem107' mRNA 1089 1173 1032 64.48 69.11 65.42 20.13 21.46 20.93 66.33666667 20.84 387 404 389 1098 393.3333333 1.32E-51 -1.490947091 GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003127///detection of nodal flow+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0010468///regulation of gene expression+++GO:0021532///neural tube patterning+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0044782///cilium organization+++GO:0060021///roof of mouth development+++GO:0060271///cilium assembly+++GO:0097094///craniofacial suture morphogenesis+++GO:1904491///protein localization to ciliary transition zone+++GO:1905515///non-motile cilium assembly 66911 66911 'Nudt16l1' mRNA 1923 2099 2008 91.2 98.34 101.09 79.92 79.82 76.85 96.87666667 78.86333333 1932 1883 1799 2010 1871.333333 0.171780248 -0.115615339 05205///Proteoglycans in cancer GO:0005634///nucleus "GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0030515///snoRNA binding+++GO:0042803///protein homodimerization activity+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides+++GO:1990174///phosphodiesterase decapping endonuclease activity" "GO:0006402///mRNA catabolic process+++GO:0016077///snoRNA catabolic process+++GO:0016311///dephosphorylation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining" 66912 66912 'Bzw2' mRNA 1382.87 1337.86 1115.5 30.57 29.22 26.55 34.62 33.94 35.56 28.78 34.70666667 1603.1 1495.28 1585.35 1278.743333 1561.243333 0.001019225 0.279900145 GO:0005737///cytoplasm GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation 66913 66913 'Kdelr2' mRNA 2938 2636 3088 91.23 80.66 101.72 130.18 141.28 132.45 91.20333333 134.6366667 4819 5105 4745 2887.333333 4889.666667 4.86E-19 0.744932143 05110///Vibrio cholerae infection GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005046///KDEL sequence binding+++GO:0046923///ER retention sequence binding "GO:0006621///protein retention in ER lumen+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport" 66914 66914 'Vps28' mRNA 2944 3012 2891 201.02 203.6 209.51 179.84 194.77 187.21 204.71 187.2733333 3010 3176 3029 2949 3071.666667 0.57610831 0.047558679 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane GO:0005515///protein binding+++GO:0043130///ubiquitin binding+++GO:0044877///protein-containing complex binding GO:0015031///protein transport+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0045732///positive regulation of protein catabolic process+++GO:2000397///positive regulation of ubiquitin-dependent endocytosis 66915 66915 'Cops9' mRNA 1511 1445 1753 321.79 309.21 396.57 355.24 403.09 391.43 342.5233333 383.2533333 1890 2077 2000 1569.666667 1989 0.002283991 0.325499612 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome GO:0003674///molecular_function GO:0008284///positive regulation of cell proliferation+++GO:0034644///cellular response to UV+++GO:0051220///cytoplasmic sequestering of protein+++GO:2000435///negative regulation of protein neddylation 66916 66916 'Ndufb7' mRNA 1913 1917 1901 292.41 292.59 308.5 263.42 316.02 299.74 297.8333333 293.06 1962 2285 2149 1910.333333 2132 0.113914527 0.147514468 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function+++GO:0003954///NADH dehydrogenase activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0032981///mitochondrial respiratory chain complex I assembly 66917 66917 'Chordc1' mRNA 1475 1453 1584 37.7 36.58 42.95 33.92 34.6 33.43 39.07666667 33.98333333 1526 1520 1456 1504 1500.666667 0.876979773 -0.017712964 GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0043531///ADP binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding GO:0010824///regulation of centrosome duplication+++GO:0051298///centrosome duplication+++GO:0061077///chaperone-mediated protein folding+++GO:1900034///regulation of cellular response to heat+++GO:2000299///negative regulation of Rho-dependent protein serine/threonine kinase activity 66921 66921 'Prpf38b' mRNA 1667 1476 1407 25.35 22.68 23.31 25.82 24.49 25.04 23.78 25.11666667 1905 1736 1768 1516.666667 1803 0.004193275 0.238333205 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071011///precatalytic spliceosome "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing" 66922 66922 'Rras2' mRNA 319 291 203 7.66 6.89 5.26 5.77 5.56 5.95 6.603333333 5.76 280 270 274 271 274.6666667 0.950946368 0.014757338 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04072///Phospholipase D signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04218///Cellular senescence+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05205///Proteoglycans in cancer GO:0000139///Golgi membrane+++GO:0005622///intracellular+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0007165///signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0009987///cellular process+++GO:0030335///positive regulation of cell migration+++GO:1901214///regulation of neuron death 66923 66923 'Pbrm1' mRNA 1348 1446 1388 8.92 9.37 9.73 9.58 8.58 9.49 9.34 9.216666667 1665 1463 1600 1394 1576 0.062701782 0.163953382 05225///Hepatocellular carcinoma GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016586///RSC-type complex+++GO:0070603///SWI/SNF superfamily-type complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding "GO:0001825///blastocyst formation+++GO:0001890///placenta development+++GO:0001974///blood vessel remodeling+++GO:0003007///heart morphogenesis+++GO:0003349///epicardium-derived cardiac endothelial cell differentiation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060948///cardiac vascular smooth muscle cell development+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0060999///positive regulation of dendritic spine development" 66925 66925 'Sdhd' mRNA 2414 2239 2939 113.9 104.28 147.12 173.97 161.67 173.22 121.7666667 169.62 4233 3837 4076 2530.666667 4048.666667 1.78E-10 0.657939385 00020///Citrate cycle (TCA cycle)+++00190///Oxidative phosphorylation+++01200///Carbon metabolism+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0016020///membrane+++GO:0016021///integral component of membrane" GO:0000104///succinate dehydrogenase activity+++GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0048039///ubiquinone binding "GO:0006099///tricarboxylic acid cycle+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0050433///regulation of catecholamine secretion+++GO:0071456///cellular response to hypoxia" 66926 66926 'Trmt6' mRNA 330 407 363 6.31 7.69 7.35 9.41 9.23 8.06 7.116666667 8.9 562 536 470 366.6666667 522.6666667 2.62E-04 0.499348546 GO:0005634///nucleus+++GO:0031515///tRNA (m1A) methyltransferase complex GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0080009///mRNA methylation 66928 66928 'Dmac1' mRNA 658 598 646 63.27 57.07 65.93 86.69 102.29 92.88 62.09 93.95333333 1031 1184 1066 634 1093.666667 3.74E-13 0.774609354 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 66929 66929 'Asf1b' mRNA 74 84 93 2.71 3.03 3.61 13.42 12.93 11.99 3.116666667 12.78 421 396 364 83.66666667 393.6666667 1.38E-35 2.219466438 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0042393///histone binding GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly 66930 66930 'Fank1' mRNA 436 433 443 12.59 12.32 13.57 1.28 1.11 1.19 12.82666667 1.193333333 51 43 46 437.3333333 46.66666667 3.87E-65 -3.242079694 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0003674///molecular_function "GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity" 66931 66931 '1700010I14Rik' mRNA 71 52 71 2.19 1.63 2.33 1.31 0.52 1.21 2.05 1.013333333 47 19 44 64.66666667 36.66666667 0.046580703 -0.840508028 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 66932 66932 'Rexo1' mRNA 1028.04 1029.01 775.16 10.14 9.97 7.95 7.32 7.87 7.42 9.353333333 7.536666667 861 894 844 944.07 866.3333333 0.288091257 -0.129765883 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity GO:0090305///nucleic acid phosphodiester bond hydrolysis 66934 66934 'Dsn1' mRNA 59 46 48 1.45 1.11 1.25 3.17 2.91 3.23 1.27 3.103333333 148 133 146 51 142.3333333 1.12E-08 1.468942368 "GO:0000444///MIS12/MIND type complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000818///nuclear MIS12/MIND complex+++GO:0000941///condensed nuclear chromosome inner kinetochore+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016604///nuclear body" GO:0003674///molecular_function GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051301///cell division 66935 66935 'Cir1' mRNA 724 804 651 21.26 23.26 20.28 15.5 15.73 14.36 21.6 15.19666667 607 601 544 726.3333333 584 0.004084792 -0.3235092 04330///Notch signaling pathway+++05169///Epstein-Barr virus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 66938 66938 'Sh3d21' mRNA 196 118 137 5.51 3.26 4.1 2.67 2.63 2.77 4.29 2.69 109 103 106 150.3333333 106 0.049199884 -0.51547896 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0007015///actin filament organization+++GO:0008150///biological_process+++GO:0016477///cell migration 66939 66939 'Aagab' mRNA 1517 1510 1520 15.23 14.91 16.19 13.67 14.31 14.18 15.44333333 14.05333333 1568 1603 1575 1515.666667 1582 0.629162351 0.049482189 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0008150///biological_process+++GO:0015031///protein transport 66940 66940 'Shisa5' mRNA 4341 4381 4390 148.94 147.62 161.5 308.99 312.63 302.51 152.6866667 308.0433333 10516 10385 10018 4370.666667 10306.33333 1.06E-103 1.224768996 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0050699///WW domain binding GO:0006915///apoptotic process+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator 66942 66942 'Ddx18' mRNA 600 582 655 15.06 14.36 17.4 15.55 17.66 17.41 15.60666667 16.87333333 714 792 774 612.3333333 760 0.015332202 0.297875012 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0071392///cellular response to estradiol stimulus" 66943 66943 'Slc66a2' mRNA 823 810 777 23.88 23.08 24.09 28 29.6 28.47 23.68333333 28.69 1118 1144 1108 803.3333333 1123.333333 1.08E-07 0.472627801 GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function "GO:0042147///retrograde transport, endosome to Golgi+++GO:0045332///phospholipid translocation" 66945 66945 'Sdha' mRNA 9704 10645 10327 187.09 201.99 211.21 166.02 162.92 161.54 200.0966667 163.4933333 9907 9495 9334 10225.33333 9578.666667 0.107776426 -0.10745424 00020///Citrate cycle (TCA cycle)+++00190///Oxidative phosphorylation+++01200///Carbon metabolism+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0016020///membrane+++GO:0043209///myelin sheath" "GO:0000104///succinate dehydrogenase activity+++GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding" "GO:0006099///tricarboxylic acid cycle+++GO:0006105///succinate metabolic process+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0007399///nervous system development+++GO:0022900///electron transport chain+++GO:0022904///respiratory electron transport chain" 66948 66948 'Acad8' mRNA 969 1063 1055 20.34 21.97 23.31 20.74 19.74 19.94 21.87333333 20.14 1123 1048 1061 1029 1077.333333 0.666806588 0.052640744 "00280///Valine, leucine and isoleucine degradation" GO:0005739///mitochondrion "GO:0003995///acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding" GO:0006574///valine catabolic process+++GO:0006629///lipid metabolic process+++GO:0009083///branched-chain amino acid catabolic process 66949 66949 'Trim59' mRNA 65 60 43 1.23 1.09 0.86 4.13 4.88 3.71 1.06 4.24 251 291 220 56 254 6.36E-22 2.175782096 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030992///intraciliary transport particle B GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell 66950 66950 'Pacc1' mRNA 451 522 556 9.53 10.86 12.46 13.35 12.6 13.55 10.95 13.16666667 727 670 714 509.6666667 703.6666667 3.45E-04 0.449778439 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005254///chloride channel activity+++GO:0061797///pH-gated chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0015698///inorganic anion transport+++GO:0098656///anion transmembrane transport 66952 66952 '2310030G06Rik' mRNA 527 561 585 25.74 27.05 30.32 17.02 16.05 15.8 27.70333333 16.29 400 368 359 557.6666667 375.6666667 4.38E-06 -0.584586903 GO:0003674///molecular_function GO:0008150///biological_process 66953 66953 'Cdca7' mRNA 46 53 41 1.07 1.24 1.03 3.93 4.29 3.88 1.113333333 4.033333333 194 204 184 46.66666667 194 4.32E-18 2.047137989 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0042127///regulation of cell proliferation" 66958 66958 'Tmx2' mRNA 4222 4285 4272 103.82 103.79 112.05 98.08 106.03 97.48 106.5533333 100.53 4574 4805 4400 4259.666667 4593 0.203424431 0.096429046 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043227///membrane-bounded organelle+++GO:0044233///Mitochondria-associated ER Membrane GO:0015036///disulfide oxidoreductase activity+++GO:0042802///identical protein binding GO:0007420///brain development 66959 66959 'Dusp26' mRNA 266 264 282 8.97 8.65 10.28 1.31 1.41 1.49 9.3 1.403333333 44 46 50 270.6666667 46.66666667 4.74E-32 -2.549731475 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0002039///p53 binding+++GO:0004647///phosphoserine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033549///MAP kinase phosphatase activity+++GO:0036424///L-phosphoserine phosphatase activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045785///positive regulation of cell adhesion+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1902310///positive regulation of peptidyl-serine dephosphorylation 66960 66960 'Mindy3' mRNA 509 522 504 11.06 11.74 12.03 16.82 16.45 16.33 11.61 16.53333333 816 771 801 511.6666667 796 9.47E-10 0.625483352 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0071108///protein K48-linked deubiquitination 66962 66962 'Swsap1' mRNA 97 100 68 3.02 3.07 2.25 1.46 1.19 1.85 2.78 1.5 54 43 66 88.33333333 54.33333333 0.029741223 -0.706694539 GO:0005634///nucleus+++GO:0097196///Shu complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0016887///ATPase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0050821///protein stabilization 66964 66964 'Golt1b' mRNA 1174 1247 1273 23.17 24.22 26.65 33.73 35.04 35.86 24.68 34.87666667 1966 1995 2025 1231.333333 1995.333333 6.73E-17 0.683285418 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 66965 66965 'Ctu2' mRNA 586.02 517.61 600.23 10.48 9.11 11.39 9.86 9.72 11.11 10.32666667 10.23 634.25 610.88 691.92 567.9533333 645.6833333 0.219974671 0.169550991 04122///Sulfur relay system GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0000049///tRNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0016783///sulfurtransferase activity GO:0002098///tRNA wobble uridine modification+++GO:0002143///tRNA wobble position uridine thiolation+++GO:0008033///tRNA processing+++GO:0032447///protein urmylation+++GO:0034227///tRNA thio-modification 66966 66966 'Trit1' mRNA 174 215 224 4.79 5.91 6.55 5.21 4.97 5.09 5.75 5.09 216 202 206 204.3333333 208 0.971083784 0.010317057 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0052381///tRNA dimethylallyltransferase activity GO:0006400///tRNA modification+++GO:0008033///tRNA processing 66967 66967 'Edem3' mRNA 669 586 517 5.35 4.62 4.39 5.32 4.98 5.15 4.786666667 5.15 764 699 716 590.6666667 726.3333333 0.013072621 0.288851105 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0044322///endoplasmic reticulum quality control compartment "GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0006516///glycoprotein catabolic process+++GO:0006986///response to unfolded protein+++GO:0008152///metabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway 66968 66968 'Plin5' mRNA 233 257 229 6.88 7.45 7.12 0.8 1.43 1.19 7.15 1.14 32 55 46 239.6666667 44.33333333 1.10E-24 -2.442335651 03320///PPAR signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035473///lipase binding+++GO:0042802///identical protein binding GO:0006629///lipid metabolic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010884///positive regulation of lipid storage+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0019915///lipid storage+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0034389///lipid droplet organization+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051646///mitochondrion localization+++GO:0060192///negative regulation of lipase activity+++GO:0060193///positive regulation of lipase activity+++GO:2000378///negative regulation of reactive oxygen species metabolic process 66970 66970 'Ssbp2' mRNA 1933.34 2155.55 1987.3 43.41 47.61 47.62 27.04 29.12 28.31 46.21333333 28.15666667 1387.49 1356.32 1378.06 2025.396667 1373.956667 3.94E-14 -0.571521227 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding GO:0045944///positive regulation of transcription by RNA polymerase II 66971 66971 'Cdk5rap1' mRNA 264 305.81 285 7.6 8.66 8.61 5.09 4.75 6.28 8.29 5.373333333 206 187 245 284.9366667 212.6666667 0.015865964 -0.432903144 GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0035596///methylthiotransferase activity+++GO:0035597///N6-isopentenyladenosine methylthiotransferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0035600///tRNA methylthiolation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045903///positive regulation of translational fidelity+++GO:0070131///positive regulation of mitochondrial translation+++GO:0070900///mitochondrial tRNA modification 66972 66972 'Slc25a23' mRNA 765 835 564 12.66 13.71 9.86 10.25 9.53 10.46 12.07666667 10.08 692 629 696 721.3333333 672.3333333 0.48032198 -0.106627943 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0002082///regulation of oxidative phosphorylation+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0015867///ATP transport+++GO:0036444///calcium import into the mitochondrion+++GO:0043457///regulation of cellular respiration+++GO:0051282///regulation of sequestering of calcium ion+++GO:0051503///adenine nucleotide transport+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0097274///urea homeostasis+++GO:1900069///regulation of cellular hyperosmotic salinity response 66973 66973 'Mrps18b' mRNA 503 516 502 28.34 29.11 30.55 47.23 40.51 42.76 29.33333333 43.5 949 807 832 507 862.6666667 6.99E-13 0.7534953 05203///Viral carcinogenesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0030054///cell junction GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 66975 66975 'Trappc13' mRNA 1235.37 1344.19 1360.09 18.98 20.33 22.19 18.42 18.54 17.95 20.5 18.30333333 1380.33 1356.13 1302.05 1313.216667 1346.17 0.863090843 0.022150892 GO:1990072///TRAPPIII protein complex GO:0003674///molecular_function 66977 66977 'Nuf2' mRNA 3 1 3 0.07 0.02 0.07 3.85 3.43 2.93 0.053333333 3.403333333 195 169 144 2.333333333 169.3333333 4.80E-24 6.167568209 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0031262///Ndc80 complex" GO:0044877///protein-containing complex binding GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0045132///meiotic chromosome segregation+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051383///kinetochore organization 66978 66978 'Luc7l' mRNA 2008 2051 2191 35.18 36.01 40.5 25.95 24.4 24.52 37.23 24.95666667 1695 1537 1569 2083.333333 1600.333333 2.80E-06 -0.395791713 GO:0005634///nucleus+++GO:0005685///U1 snRNP+++GO:0071004///U2-type prespliceosome GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0050733///RS domain binding GO:0006376///mRNA splice site selection+++GO:0045843///negative regulation of striated muscle tissue development 66979 66979 'Pole4' mRNA 1698.85 1746.79 1679.17 59.12 60.5 62.52 64.63 65.1 63.02 60.71333333 64.25 2121.32 2092.2 2005.03 1708.27 2072.85 2.60E-04 0.26753378 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0008622///epsilon DNA polymerase complex GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity 66980 66980 'Zdhhc6' mRNA 1023 1079 1020 25.3 26.24 26.77 30.94 34.81 32.14 26.10333333 32.63 1440 1579 1448 1040.666667 1489 5.92E-09 0.506075753 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005515///protein binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0043543///protein acylation 66983 66983 'Zfp830' mRNA 538.8 562.01 600.99 8.98 9.21 10.62 9.47 9.5 10.05 9.603333333 9.673333333 654.35 641 672.06 567.2666667 655.8033333 0.119365718 0.196283994 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005694///chromosome+++GO:0016607///nuclear speck GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0000278///mitotic cell cycle+++GO:0001541///ovarian follicle development+++GO:0001546///preantral ovarian follicle growth+++GO:0001832///blastocyst growth+++GO:0006397///mRNA processing+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0033260///nuclear DNA replication+++GO:0033314///mitotic DNA replication checkpoint+++GO:0043066///negative regulation of apoptotic process+++GO:0044773///mitotic DNA damage checkpoint+++GO:0048478///replication fork protection+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0060729///intestinal epithelial structure maintenance 66985 66985 'Rassf7' mRNA 437.07 429 489.43 16.4 16.22 19.72 15.17 14.68 14.77 17.44666667 14.87333333 460 432.53 439.86 451.8333333 444.13 0.826770359 -0.04141404 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0070507///regulation of microtubule cytoskeleton organization 66988 66988 'Lap3' mRNA 1345 1416 1322 33.35 34.58 34.77 44.35 44.3 45.93 34.23333333 44.86 2057 2006 2062 1361 2041.666667 1.06E-15 0.573702037 00330///Arginine and proline metabolism+++00480///Glutathione metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0030496///midbody GO:0004177///aminopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0019538///protein metabolic process 66989 66989 'Kctd20' mRNA 1285 1323 1361 18.05 18.25 20.32 18.71 18.74 16.32 18.87333333 17.92333333 1541 1510 1301 1323 1450.666667 0.267421976 0.119003215 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0042327///positive regulation of phosphorylation 66990 66990 'Tmem134' mRNA 1427 1457 1245 56.44 56.91 52.29 61.86 64.8 63.93 55.21333333 63.53 1797 1837 1794 1376.333333 1809.333333 4.17E-07 0.385717768 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 66991 66991 'Khdc3' mRNA 1 0 0 0.01 0 0 0.05 0.09 0.01 0.003333333 0.05 2 3 1 0.333333333 2 0.381530071 2.471966272 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005938///cell cortex+++GO:0032991///protein-containing complex+++GO:0045179///apical cortex GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006468///protein phosphorylation+++GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007275///multicellular organism development+++GO:0031297///replication fork processing+++GO:0032880///regulation of protein localization+++GO:0040019///positive regulation of embryonic development+++GO:0043066///negative regulation of apoptotic process+++GO:0050769///positive regulation of neurogenesis+++GO:0051656///establishment of organelle localization+++GO:0090307///mitotic spindle assembly+++GO:1900006///positive regulation of dendrite development+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2000781///positive regulation of double-strand break repair 66993 66993 'Smarcd3' mRNA 136.58 145.26 97.26 3.9 3.98 2.75 3.48 3.52 3.61 3.543333333 3.536666667 135.06 126.67 139.54 126.3666667 133.7566667 0.809700262 0.07632556 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016922///nuclear receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035257///nuclear hormone receptor binding "GO:0002052///positive regulation of neuroblast proliferation+++GO:0003007///heart morphogenesis+++GO:0003139///secondary heart field specification+++GO:0003219///cardiac right ventricle formation+++GO:0003407///neural retina development+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0042692///muscle cell differentiation+++GO:0043393///regulation of protein binding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051152///positive regulation of smooth muscle cell differentiation" 66994 66994 'Cep19' mRNA 983 1060 988 32.96 35.03 35.14 17.15 15.13 15.23 34.37666667 15.83666667 588 506 505 1010.333333 533 8.07E-21 -0.935389931 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function "GO:0030030///cell projection organization+++GO:0034454///microtubule anchoring at centrosome+++GO:0060271///cilium assembly+++GO:0097712///vesicle targeting, trans-Golgi to periciliary membrane compartment" 66995 66995 'Zcchc18' mRNA 4135 4311 3980 92.87 94.25 94.53 23.47 23.45 23.52 93.88333333 23.48 1184 1181 1163 4142 1176 3.73E-183 -1.827488655 GO:0005634///nucleus GO:0046872///metal ion binding 66997 66997 'Psmd12' mRNA 1474 1553 1475 49.58 51.49 52.63 61.67 64.33 62.43 51.23333333 62.81 2107 2145 2064 1500.666667 2105.333333 6.77E-11 0.476944848 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0005838///proteasome regulatory particle+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex+++GO:0031595///nuclear proteasome complex" GO:0003674///molecular_function GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 66998 66998 'Psmd5' mRNA 1404 1493 1597 39.22 41.06 47.25 38.66 40.24 37.84 42.51 38.91333333 1588 1620 1503 1498 1570.333333 0.660139591 0.053422503 "GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0022624///proteasome accessory complex" GO:0043248///proteasome assembly+++GO:0070682///proteasome regulatory particle assembly 66999 66999 'Med28' mRNA 2312 2385 2280 27.15 27.54 28.4 28.36 30.38 29.36 27.69666667 29.36666667 2781 2910 2788 2325.666667 2826.333333 1.02E-04 0.270028325 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0030864///cortical actin cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding GO:0019827///stem cell population maintenance+++GO:0051151///negative regulation of smooth muscle cell differentiation 67003 67003 'Uqcrc2' mRNA 3363.59 3355.79 3267.81 102.46 100.73 105.6 97.73 92.22 97.61 102.93 95.85333333 3687.83 3396.91 3564.83 3329.063333 3549.856667 0.256171083 0.080082528 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0042493///response to drug 67005 67005 'Polr3k' mRNA 701 804 755 13.19 14.89 15.07 18.3 20.01 17.58 14.38333333 18.63 1119 1195 1041 753.3333333 1118.333333 4.22E-08 0.558385022 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006351///transcription, DNA-templated+++GO:0006386///termination of RNA polymerase III transcription+++GO:0042779///tRNA 3'-trailer cleavage+++GO:0045087///innate immune response+++GO:0051607///defense response to virus" 67006 67006 'Cisd2' mRNA 1875 1871 1817 36.01 35.37 37.02 32.39 30.45 30.79 36.13333333 31.21 1940 1781 1786 1854.333333 1835.666667 0.787159338 -0.027129945 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum "GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0010259///multicellular organism aging+++GO:0010506///regulation of autophagy 67008 67008 'Yae1d1' mRNA 950 1026 998 15.05 15.99 16.77 19.06 18.54 19.52 15.93666667 19.04 1384 1315 1373 991.3333333 1357.333333 3.04E-07 0.440647591 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0106035///protein maturation by [4Fe-4S] cluster transfer 67009 67009 'Ttc23' mRNA 359 367 365 7.12 7.23 8.18 6.39 5.12 6.7 7.51 6.07 358 299 352 363.6666667 336.3333333 0.457594631 -0.126309728 GO:0005929///cilium+++GO:0042995///cell projection GO:0045880///positive regulation of smoothened signaling pathway 67010 67010 'Rbm7' mRNA 1410 1487 1516 44.99 46.64 51.21 50.05 51.57 52.16 47.61333333 51.26 1807 1815 1820 1471 1814 5.34E-04 0.289141059 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding+++GO:0017069///snRNA binding+++GO:0071889///14-3-3 protein binding+++GO:0097157///pre-mRNA intronic binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0016076///snRNA catabolic process+++GO:0051321///meiotic cell cycle" 67011 67011 'Mettl6' mRNA 444 430 441 13.15 12.75 13.38 15.08 15.09 17.83 13.09333333 16 592.03 584 664 438.3333333 613.3433333 1.04E-04 0.472291636 GO:0005575///cellular_component GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0052735///tRNA (cytosine-3-)-methyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 67013 67013 'Oma1' mRNA 319 291 315 8.56 7.65 8.38 10.91 11.94 12.97 8.196666667 11.94 484 516 534 308.3333333 511.3333333 7.71E-08 0.717390768 05017///Spinocerebellar ataxia GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002024///diet induced thermogenesis+++GO:0006006///glucose metabolic process+++GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0006629///lipid metabolic process+++GO:0007005///mitochondrion organization+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016540///protein autoprocessing+++GO:0031638///zymogen activation+++GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0034982///mitochondrial protein processing+++GO:0042407///cristae formation+++GO:0043065///positive regulation of apoptotic process+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0097009///energy homeostasis+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1903850///regulation of cristae formation 67014 67014 'Riox2' mRNA 459.35 436.91 404.28 11.84 11.05 11.16 12.68 13.63 13.43 11.35 13.24666667 557.15 590.52 575.46 433.5133333 574.3766667 9.17E-04 0.396875763 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005829///cytosol "GO:0003714///transcription corepressor activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)" "GO:0008283///cell proliferation+++GO:0034720///histone H3-K4 demethylation+++GO:0042127///regulation of cell proliferation+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070544///histone H3-K36 demethylation" 67015 67015 'Ccdc91' mRNA 885 956 891 20.16 21.22 21.7 13.48 13.37 11.98 21.02666667 12.94333333 680 648 589 910.6666667 639 2.23E-07 -0.523159772 GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0042802///identical protein binding GO:0015031///protein transport+++GO:0048193///Golgi vesicle transport+++GO:0090160///Golgi to lysosome transport 67016 67016 'Tbc1d2b' mRNA 123 94 113 1.16 0.87 1.13 2.59 2.6 2.79 1.053333333 2.66 318 313 332 110 321 1.77E-17 1.531807242 GO:0005829///cytosol GO:0005096///GTPase activator activity GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 67017 67017 'Fam210b' mRNA 1200 1300 1210 18.89 20.13 20.22 13.35 15.02 13.03 19.74666667 13.8 930 926 899 1236.666667 918.3333333 3.58E-07 -0.44087749 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane GO:0003674///molecular_function GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0071392///cellular response to estradiol stimulus 67019 67019 'Actr6' mRNA 384 371 335 12.9 12.36 12 10.68 10.03 9.94 12.42 10.21666667 365 333 327 363.3333333 341.6666667 0.557456194 -0.099459074 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0031491///nucleosome binding GO:0006338///chromatin remodeling+++GO:0043486///histone exchange 67020 67020 'Tmem88' mRNA 79.59 105.17 85.87 2.94 3.84 3.37 6.03 6.51 6.12 3.383333333 6.22 187.47 197.35 184.04 90.21 189.62 7.78E-07 1.068766391 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030165///PDZ domain binding GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0050821///protein stabilization+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway 670211 670211 'Gm12508' mRNA 26.9 28.57 36.28 2.84 2.99 4.06 5.19 3.45 4.41 3.296666667 4.35 56.24 36.41 46.07 30.58333333 46.24 0.193487621 0.595451347 67023 67023 'Use1' mRNA 1459 1459 1352 110.41 109.52 107.62 76.09 76.5 74.8 109.1833333 75.79666667 1152 1134 1109 1423.333333 1131.666667 1.67E-05 -0.341693579 04130///SNARE interactions in vesicular transport GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030137///COPI-coated vesicle+++GO:0031201///SNARE complex GO:0005484///SNAP receptor activity+++GO:0005515///protein binding "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007029///endoplasmic reticulum organization+++GO:0007041///lysosomal transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030163///protein catabolic process+++GO:0032940///secretion by cell+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0071786///endoplasmic reticulum tubular network organization" 67025 67025 'Rpl11' mRNA 2728 2698 2489 162.98 157.83 156.09 203.12 207.1 211.67 158.9666667 207.2966667 3908 3880 3927 2638.333333 3905 3.13E-21 0.55519844 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0032991///protein-containing complex+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0019843///rRNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0000027///ribosomal large subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0006605///protein targeting+++GO:0010628///positive regulation of gene expression+++GO:0032092///positive regulation of protein binding+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034504///protein localization to nucleus+++GO:0042273///ribosomal large subunit biogenesis+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0050821///protein stabilization+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2000435///negative regulation of protein neddylation 67026 67026 'Thap4' mRNA 481 561 435 17.55 20.98 17.59 18.86 16.83 18.95 18.70666667 18.21333333 523 468 524 492.3333333 505 0.863090843 0.027829127 GO:0005575///cellular_component GO:0003677///DNA binding+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0070026///nitric oxide binding GO:0006570///tyrosine metabolic process+++GO:0042126///nitrate metabolic process 67027 67027 'Mkrn2' mRNA 1209.05 1244.06 1334.6 25.79 25.59 30.02 15.76 14.69 16.44 27.13333333 15.63 901.37 823.28 895.86 1262.57 873.5033333 1.72E-08 -0.547108173 GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination 67028 67028 '2610002M06Rik' mRNA 379 398 431 3.45 3.56 4.16 2.99 2.99 3.28 3.723333333 3.086666667 379 370 402 402.6666667 383.6666667 0.63852288 -0.084246045 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030496///midbody+++GO:0031902///late endosome membrane GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0090541///MIT domain binding GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0045184///establishment of protein localization+++GO:0045324///late endosome to vacuole transport+++GO:0051301///cell division+++GO:0061952///midbody abscission+++GO:1901673///regulation of mitotic spindle assembly 67030 67030 'Fancl' mRNA 306.03 353.03 318.75 9.91 11.27 10.95 8.81 7.3 7.65 10.71 7.92 312.63 252.87 262.72 325.9366667 276.0733333 0.126946416 -0.255193507 03460///Fanconi anemia pathway+++04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043240///Fanconi anaemia nuclear complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006281///DNA repair+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007276///gamete generation+++GO:0016567///protein ubiquitination+++GO:0036297///interstrand cross-link repair+++GO:0042127///regulation of cell proliferation 67031 67031 'Upf3a' mRNA 945 919 601 33.88 32.44 22.31 18.65 27.54 23.55 29.54333333 23.24666667 604 854 725 821.6666667 727.6666667 0.332891333 -0.174568979 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0042162///telomeric DNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006986///response to unfolded protein+++GO:0045727///positive regulation of translation" 67035 67035 'Dnajb4' mRNA 1321 1362 1348 18.51 18.86 20.08 12.64 11.77 12.3 19.15 12.23666667 1028 952 971 1343.666667 983.6666667 5.06E-08 -0.463023687 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0001671///ATPase activator activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0050790///regulation of catalytic activity+++GO:0051085///chaperone cofactor-dependent protein refolding 67036 67036 'Mrpl45' mRNA 816 782 776 18.72 17.65 18.85 22.57 22.88 21.14 18.40666667 22.19666667 1133 1122 1028 791.3333333 1094.333333 1.05E-06 0.455659607 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0008150///biological_process 67037 67037 'Pmf1' mRNA 512 486 490 29.74 28.57 30.47 42.19 39.22 40.82 29.59333333 40.74333333 832 752 779 496 787.6666667 4.51E-10 0.65442575 "GO:0000444///MIS12/MIND type complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle" GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0043522///leucine zipper domain binding "GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division" 67038 67038 'Ly6m' mRNA 0 0 3 0 0 0.1 0.42 0.16 0.11 0.033333333 0.23 16 6 4 1 8.666666667 0.046580703 3.055643634 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0030550///acetylcholine receptor inhibitor activity GO:2000272///negative regulation of signaling receptor activity 67039 67039 'Rbm25' mRNA 2159.4 2412.4 2096.59 26.99 29.66 27.85 32.84 30.07 30.93 28.16666667 31.28 3018.7 2697.32 2753.76 2222.796667 2823.26 2.03E-06 0.333812519 03040///Spliceosome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0042981///regulation of apoptotic process" 67040 67040 'Ddx17' mRNA 2664 2737 2111 35.15 35.56 28.09 26.39 22.06 26.25 32.93333333 24.9 2353 2000 2314 2504 2222.333333 0.049341006 -0.180029105 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0001837///epithelial to mesenchymal transition+++GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010586///miRNA metabolic process+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0030521///androgen receptor signaling pathway+++GO:0031047///gene silencing by RNA+++GO:0045445///myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:2001014///regulation of skeletal muscle cell differentiation" 67041 67041 'Oxct1' mRNA 2691 2852 2658 42.04 43.84 44.05 56.49 53.52 55.02 43.31 55.01 4161 3851 3925 2733.666667 3979 1.37E-18 0.529562892 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008260///3-oxoacid CoA-transferase activity+++GO:0008410///CoA-transferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding GO:0006104///succinyl-CoA metabolic process+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007584///response to nutrient+++GO:0009725///response to hormone+++GO:0014823///response to activity+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042182///ketone catabolic process+++GO:0042493///response to drug+++GO:0042594///response to starvation+++GO:0045471///response to ethanol+++GO:0046950///cellular ketone body metabolic process+++GO:0046952///ketone body catabolic process+++GO:0060612///adipose tissue development 67042 67042 'Ift27' mRNA 1131 1121 931 73.22 71.78 63.96 34.84 37.02 37.63 69.65333333 36.49666667 617 639 644 1061 633.3333333 7.97E-15 -0.752287151 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097225///sperm midpiece+++GO:0097228///sperm principal piece GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0001822///kidney development+++GO:0006886///intracellular protein transport+++GO:0007224///smoothened signaling pathway+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0042073///intraciliary transport+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0090102///cochlea development 67043 67043 'Syap1' mRNA 1029 1005 304 24.92 23.97 7.81 9.5 21.01 17.01 18.9 15.84 451 974 782 779.3333333 735.6666667 0.939808631 -0.063428394 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0030154///cell differentiation+++GO:0032869///cellular response to insulin stimulus+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0038203///TORC2 signaling+++GO:0045600///positive regulation of fat cell differentiation+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1990314///cellular response to insulin-like growth factor stimulus 67044 67044 'Higd2a' mRNA 2051 1958 1804 253.2 240.59 236.39 231.4 259.97 230.32 243.3933333 240.5633333 2139 2336 2052 1937.666667 2175.666667 0.065134436 0.157644402 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0043066///negative regulation of apoptotic process+++GO:0097250///mitochondrial respiratory chain supercomplex assembly 67045 67045 'Riok2' mRNA 324 341 321 5.54 5.74 5.83 5.71 6 6.33 5.703333333 6.013333333 384 394 412 328.6666667 396.6666667 0.07172936 0.260278674 03008///Ribosome biogenesis in eukaryotes "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030688///preribosome, small subunit precursor" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis+++GO:0042274///ribosomal small subunit biogenesis+++GO:0046777///protein autophosphorylation+++GO:2000208///positive regulation of ribosomal small subunit export from nucleus+++GO:2000234///positive regulation of rRNA processing 67046 67046 'Tbc1d7' mRNA 1017 957 921 57.81 54.11 56.01 21.12 20.56 20.37 55.97666667 20.68333333 454 433 434 965 440.3333333 1.13E-30 -1.143378084 04150///mTOR signaling pathway GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0031398///positive regulation of protein ubiquitination+++GO:0032007///negative regulation of TOR signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0070848///response to growth factor+++GO:0090630///activation of GTPase activity+++GO:1902018///negative regulation of cilium assembly 670464 670464 'Gm11596' mRNA 0 0 1 0 0 0.11 0 0 0 0.036666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 67048 67048 'Vma21' mRNA 1148 1281 1095 14.72 16.16 14.89 16.83 15.75 16.24 15.25666667 16.27333333 1512 1382 1412 1174.666667 1435.333333 9.09E-04 0.278569143 GO:0005764///lysosome+++GO:0005773///vacuole+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly 67049 67049 'Pus3' mRNA 290 287 233 6.91 6.74 5.89 5.08 4.25 5.52 6.513333333 4.95 245 200 258 270 234.3333333 0.265476503 -0.213505211 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:0106029///tRNA pseudouridine synthase activity GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0031119///tRNA pseudouridine synthesis+++GO:1990481///mRNA pseudouridine synthesis 670496 670496 'Gm11564' mRNA 0 1 0 0 0.1 0 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 67050 67050 'Nkap' mRNA 583 670 619 7.36 8.32 8.29 6.89 7.36 6.23 7.99 6.826666667 628 656 550 624 611.3333333 0.80407773 -0.041183661 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003682///chromatin binding+++GO:0031490///chromatin DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0010468///regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0030097///hemopoiesis+++GO:0030851///granulocyte differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0071425///hematopoietic stem cell proliferation" 67052 67052 'Ndc80' mRNA 7 9 5 0.18 0.23 0.14 3.63 3.44 3.89 0.183333333 3.653333333 163 151 169 7 161 2.23E-29 4.514775657 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0031262///Ndc80 complex" GO:0005515///protein binding+++GO:0030332///cyclin binding+++GO:0042802///identical protein binding GO:0000070///mitotic sister chromatid segregation+++GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0007059///chromosome segregation+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008315///G2/MI transition of meiotic cell cycle+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0031647///regulation of protein stability+++GO:0051298///centrosome duplication+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051383///kinetochore organization+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:1905342///positive regulation of protein localization to kinetochore 67053 67053 'Rpp14' mRNA 642.02 635.87 619 14.52 14.15 14.85 13.13 13.27 12.2 14.50666667 12.86666667 668.01 659.1 600.88 632.2966667 642.6633333 0.937599015 0.011433335 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0030677///ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 67054 67054 'Paics' mRNA 3657 3770.2 3827 95.6 97.31 106.35 92.05 90.08 89.6 99.75333333 90.57666667 4021.72 3844.55 3794 3751.4 3886.756667 0.672670215 0.037334067 00230///Purine metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004638///phosphoribosylaminoimidazole carboxylase activity+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0043727///5-amino-4-imidazole carboxylate lyase activity GO:0006164///purine nucleotide biosynthetic process+++GO:0006177///GMP biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0008152///metabolic process+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0097294///'de novo' XMP biosynthetic process 670558 670558 'H60c' mRNA 0 1 0 0 0.02 0 0.07 0.1 0.02 0.006666667 0.063333333 4 6 1 0.333333333 3.666666667 0.138006846 3.346183839 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane+++GO:0046658///anchored component of plasma membrane GO:0046703///natural killer cell lectin-like receptor binding GO:0002376///immune system process+++GO:0006955///immune response+++GO:0042267///natural killer cell mediated cytotoxicity 67057 67057 'Yaf2' mRNA 639 640 427 18.21 18.11 12.82 13.88 17.98 15.77 16.38 15.87666667 549 688 596 568.6666667 611 0.583749235 0.10205748 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 67059 67059 'Ola1' mRNA 444 356 428 13.11 11.41 14.14 16.33 15.8 14.64 12.88666667 15.59 596 537 522 409.3333333 551.6666667 0.002889767 0.415021841 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0043022///ribosome binding+++GO:0043023///ribosomal large subunit binding+++GO:0046872///metal ion binding GO:0046034///ATP metabolic process 670593 670593 'Gm9495' mRNA 14.15 6.03 9.23 0.27 0.11 0.19 0.02 0.03 0.02 0.19 0.023333333 1 2 1.01 9.803333333 1.336666667 0.02405672 -2.867911944 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67062 67062 'Slc25a53' mRNA 65 81 86 1.01 1.28 1.54 0.67 0.65 0.6 1.276666667 0.64 45 43 42 77.33333333 43.33333333 0.011035763 -0.851391333 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67063 67063 'Pgap4' mRNA 610 724 423 16.88 19.21 12.84 9.38 11.59 10.2 16.31 10.39 386 472 398 585.6666667 418.6666667 0.003736147 -0.484263228 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006506///GPI anchor biosynthetic process 67064 67064 'Chmp1b' mRNA 696 838 753 15.32 18.16 17.58 24.03 24.55 22.47 17.02 23.68333333 1256 1253 1137 762.3333333 1215.333333 1.94E-11 0.661278589 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030496///midbody+++GO:0031902///late endosome membrane GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0090541///MIT domain binding GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0045184///establishment of protein localization+++GO:0045324///late endosome to vacuole transport+++GO:0051301///cell division+++GO:0061952///midbody abscission+++GO:1901673///regulation of mitotic spindle assembly 67065 67065 'Polr3d' mRNA 388 365 349 11.48 10.65 11.16 10.15 11.99 11.07 11.09666667 11.07 405 474 422 367.3333333 433.6666667 0.121215121 0.229879615 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus 67067 67067 'Romo1' mRNA 1177 1140 1355 231.56 225.18 283.63 202.39 230.92 230.54 246.79 221.2833333 1171 1292 1270 1224 1244.333333 0.958024763 0.008232666 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008284///positive regulation of cell proliferation+++GO:0030150///protein import into mitochondrial matrix+++GO:0031640///killing of cells of other organism+++GO:0034614///cellular response to reactive oxygen species+++GO:0042742///defense response to bacterium+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051838///cytolysis by host of symbiont cells+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090399///replicative senescence+++GO:2000379///positive regulation of reactive oxygen species metabolic process 67068 67068 'Dynlrb1' mRNA 3164 3122 3014 330.34 323.53 333.6 374.95 393.56 366.05 329.1566667 378.1866667 4145 4212 3897 3100 4084.666667 1.06E-09 0.386451785 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement+++GO:0007632///visual behavior+++GO:0009416///response to light stimulus 67070 67070 'Lsm14a' mRNA 950 969 573 17.68 17.88 11.34 12.38 12.82 12.82 15.63333333 12.67333333 773 773 779 830.6666667 775 0.576551035 -0.100915228 GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010494///cytoplasmic stress granule+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0072686///mitotic spindle+++GO:1990124///messenger ribonucleoprotein complex GO:0003690///double-stranded DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0017148///negative regulation of translation+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly+++GO:0039529///RIG-I signaling pathway+++GO:0051607///defense response to virus+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0090307///mitotic spindle assembly 67071 67071 'Rps6ka6' mRNA 147 157 145 1.83 1.96 1.95 0.58 0.77 1.06 1.913333333 0.803333333 55 70 93 149.6666667 72.66666667 5.22E-05 -1.051302741 04010///MAPK signaling pathway+++04114///Oocyte meiosis+++04150///mTOR signaling pathway+++04714///Thermogenesis+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04931///Insulin resistance+++05135///Yersinia infection+++05207///Chemical carcinogenesis - receptor activation GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0006468///protein phosphorylation+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0045992///negative regulation of embryonic development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2000381///negative regulation of mesoderm development" 67072 67072 'Cdc37l1' mRNA 2583.09 2738.27 2609.51 34.71 35.69 36.45 26.99 25.07 25.21 35.61666667 25.75666667 2439.31 2181.67 2165.31 2643.623333 2262.096667 0.00109966 -0.237945784 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0031072///heat shock protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0050821///protein stabilization 67073 67073 'Pi4k2b' mRNA 396 432 146 6.97 7.47 2.74 3.75 5.92 4.81 5.726666667 4.826666667 243 378 304 324.6666667 308.3333333 0.927609284 -0.060110459 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004430///1-phosphatidylinositol 4-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0007030///Golgi organization+++GO:0007032///endosome organization+++GO:0016310///phosphorylation+++GO:0046854///phosphatidylinositol phosphorylation 67074 67074 'Mon2' mRNA 1017 926 919 6.11 5.64 6.26 6.64 6.63 6.83 6.003333333 6.7 1230 1178 1208 954 1205.333333 2.51E-04 0.32564651 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane GO:0006895///Golgi to endosome transport+++GO:0015031///protein transport 67075 67075 'Magt1' mRNA 2175.28 2134.53 2130.65 26.71 25.68 27.7 35.07 32.61 33.73 26.69666667 33.80333333 3300.3 2988.28 3067.32 2146.82 3118.633333 3.22E-15 0.525754557 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015095///magnesium ion transmembrane transporter activity GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0015693///magnesium ion transport+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0050890///cognition+++GO:1903830///magnesium ion transmembrane transport 67077 67077 'Catsperz' mRNA 13 7 7 1.14 0.61 0.65 1 0.39 0.88 0.8 0.756666667 13 5 11 9 9.666666667 0.935098771 0.089829105 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0005515///protein binding GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0048240///sperm capacitation 67078 67078 'Pgp' mRNA 2595 2571 2032 55.59 54.22 46.17 36.09 42.83 40.54 51.99333333 39.82 1938 2246 2108 2399.333333 2097.333333 0.037404062 -0.199483361 00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism GO:0005737///cytoplasm "GO:0000121///glycerol-1-phosphatase activity+++GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008967///phosphoglycolate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043136///glycerol-3-phosphatase activity+++GO:0046872///metal ion binding+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides" GO:0005975///carbohydrate metabolic process+++GO:0006114///glycerol biosynthetic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045721///negative regulation of gluconeogenesis 67080 67080 '1700019D03Rik' mRNA 252 221 226 3.77 3.26 3.61 1.93 1.75 1.7 3.546666667 1.793333333 148 131 126 233 135 2.00E-05 -0.80019805 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0034237///protein kinase A regulatory subunit binding GO:0008150///biological_process 67082 67082 'ccdc198' mRNA 11 0 4 0.58 0 0.22 0 0.09 0.05 0.266666667 0.046666667 0 2 1 5 1 0.23914165 -2.322413136 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 670832 670832 'Rps12-ps10' mRNA 1.01 0 3.12 0.17 0 0.55 0.15 0.49 0.46 0.24 0.366666667 1 3.26 3.06 1.376666667 2.44 0.755246974 0.766818324 67085 67085 '1700024G13Rik' mRNA 171 168 206 43.57 43.18 55.79 4.74 4.66 4.7 47.51333333 4.7 21 20 20 181.6666667 20.33333333 6.44E-27 -3.176980143 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67087 67087 'Ctnnbip1' mRNA 963 974 647 20 19.94 14.31 13.11 17.71 15.99 18.08333333 15.60333333 726 958 858 861.3333333 847.3333333 0.894541385 -0.024236872 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030877///beta-catenin destruction complex GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0070016///armadillo repeat domain binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0002528///regulation of vascular permeability involved in acute inflammatory response+++GO:0009952///anterior/posterior pattern specification+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031333///negative regulation of protein complex assembly+++GO:0032091///negative regulation of protein binding+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0060633///negative regulation of transcription initiation from RNA polymerase II promoter+++GO:0072201///negative regulation of mesenchymal cell proliferation 67088 67088 'Cand2' mRNA 489.25 597.41 513.99 4.93 5.74 5.44 3.2 3.48 3.74 5.37 3.473333333 376.9 395.81 421.4 533.55 398.0366667 0.001074872 -0.433736661 GO:0005634///nucleus+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0017025///TBP-class protein binding GO:0010265///SCF complex assembly+++GO:0016567///protein ubiquitination 670880 670880 'Gm9507' mRNA 1 1 0 0.05 0.05 0 0 0 0 0.033333333 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 67089 67089 'Psmc6' mRNA 1523 1656 1535 51.63 56.12 55.29 73.63 71.22 72.26 54.34666667 72.37 2426 2275 2301 1571.333333 2334 1.83E-15 0.558899281 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0016234///inclusion body+++GO:0022624///proteasome accessory complex+++GO:0031597///cytosolic proteasome complex" GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0036402///proteasome-activating ATPase activity+++GO:0042802///identical protein binding GO:0030163///protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0090261///positive regulation of inclusion body assembly+++GO:1901800///positive regulation of proteasomal protein catabolic process 67091 67091 'Trappc6a' mRNA 889 887 862 73.12 71.96 74.83 52.12 60.23 53.7 73.30333333 55.35 730 820 722 879.3333333 757.3333333 0.037635083 -0.226354518 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0030008///TRAPP complex GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0043087///regulation of GTPase activity+++GO:0043473///pigmentation+++GO:0048193///Golgi vesicle transport+++GO:1903232///melanosome assembly 67092 67092 'Gatm' mRNA 1615 1638 1608 38.37 38.32 40.53 90.35 89.27 88.33 39.07333333 89.31666667 4373 4219 4139 1620.333333 4243.666667 4.46E-106 1.376642349 "00260///Glycine, serine and threonine metabolism+++00330///Arginine and proline metabolism" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane GO:0015067///amidinotransferase activity+++GO:0015068///glycine amidinotransferase activity+++GO:0016740///transferase activity GO:0006600///creatine metabolic process+++GO:0006601///creatine biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007584///response to nutrient+++GO:0007611///learning or memory+++GO:0010033///response to organic substance+++GO:0014889///muscle atrophy+++GO:0043434///response to peptide hormone+++GO:0046689///response to mercury ion+++GO:0120162///positive regulation of cold-induced thermogenesis 67095 67095 'Trak1' mRNA 2588 2376 2200 29.54 26.53 26.39 10.74 11.04 11.43 27.48666667 11.07 1079 1086 1122 2388 1095.666667 1.70E-50 -1.133810597 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm+++GO:1904115///axon cytoplasm GO:0005102///signaling receptor binding+++GO:0017022///myosin binding+++GO:0030911///TPR domain binding+++GO:0050811///GABA receptor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006493///protein O-linked glycosylation+++GO:0006605///protein targeting+++GO:0008333///endosome to lysosome transport+++GO:0019896///axonal transport of mitochondrion+++GO:0022008///neurogenesis+++GO:0047496///vesicle transport along microtubule+++GO:0048311///mitochondrion distribution+++GO:0048813///dendrite morphogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0098957///anterograde axonal transport of mitochondrion 67096 67096 'Mmachc' mRNA 478.03 487.34 491.35 14.16 14.22 15.44 14.01 12.47 13.09 14.60666667 13.19 543.91 472.3 491.58 485.5733333 502.5966667 0.843314991 0.03491869 04977///Vitamin digestion and absorption GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0031419///cobalamin binding+++GO:0032451///demethylase activity+++GO:0033787///cyanocobalamin reductase (cyanide-eliminating) activity+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding+++GO:0071949///FAD binding GO:0006749///glutathione metabolic process+++GO:0009235///cobalamin metabolic process+++GO:0070988///demethylation 67097 67097 'Rps10' mRNA 1812 1739 1699 237.39 226.96 236.28 322.58 312.21 344.8 233.5433333 326.53 2808 2641 2892 1750 2780.333333 1.86E-21 0.656016257 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0000028///ribosomal small subunit assembly 67099 67099 'Mettl21a' mRNA 659 644 657 13.8 13.11 14.45 14.99 14.51 12.96 13.78666667 14.15333333 813 771 685 653.3333333 756.3333333 0.093345966 0.197884087 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0051117///ATPase binding GO:0006479///protein methylation+++GO:0018022///peptidyl-lysine methylation+++GO:0032259///methylation 67101 67101 '2310039H08Rik' mRNA 420 381 392 37.44 33.68 37.08 44.02 41.37 39.71 36.06666667 41.7 565 517 492 397.6666667 524.6666667 0.002514424 0.386860648 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67102 67102 'D16Ertd472e' mRNA 69 85 92 0.6 0.73 0.84 1.01 0.83 1.14 0.723333333 0.993333333 132 107 146 82 128.3333333 0.01969946 0.629752163 GO:0005575///cellular_component GO:0005515///protein binding GO:0007399///nervous system development+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030154///cell differentiation+++GO:0060999///positive regulation of dendritic spine development 67103 67103 'Ptgr1' mRNA 62 70 92 2.32 2.88 3.72 19.28 18.88 21.32 2.973333333 19.82666667 550 531 585 74.66666667 555.3333333 7.39E-61 2.878488081 GO:0005737///cytoplasm "GO:0016491///oxidoreductase activity+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0032440///2-alkenal reductase [NAD(P)] activity+++GO:0035798///2-alkenal reductase (NADP+) activity+++GO:0036132///13-prostaglandin reductase activity+++GO:0036185///13-lipoxin reductase activity+++GO:0047522///15-oxoprostaglandin 13-oxidase activity+++GO:0097257///leukotriene B4 12-hydroxy dehydrogenase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0036102///leukotriene B4 metabolic process+++GO:0097327///response to antineoplastic agent+++GO:2001302///lipoxin A4 metabolic process 67105 67105 'Timm21' mRNA 628 658 707 15.33 16.03 18.41 11.97 13.71 13.18 16.59 12.95333333 573 640 616 664.3333333 609.6666667 0.322368749 -0.137369567 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0033617///mitochondrial respiratory chain complex IV assembly 67106 67106 'Zbtb8os' mRNA 856.31 856.3 763.12 16.19 16.4 15.42 14.57 14.87 15.25 16.00333333 14.89666667 878.85 902.44 888.23 825.2433333 889.84 0.368240735 0.098685585 GO:0072669///tRNA-splicing ligase complex GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0008033///tRNA processing" 67109 67109 'Zfp787' mRNA 608 643 186 17.95 18.62 5.71 4.83 8.36 7.74 14.09333333 6.976666667 190 322 294 479 268.6666667 0.204327242 -0.816286022 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 67111 67111 'Naaa' mRNA 486 576 509 11.2 13.07 12.44 17.47 17.07 17.57 12.23666667 17.37 872 832 849 523.6666667 851 4.82E-11 0.68924972 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane "GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0017064///fatty acid amide hydrolase activity+++GO:0047412///N-(long-chain-acyl)ethanolamine deacylase activity+++GO:0102121///ceramidase activity" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0016042///lipid catabolic process+++GO:0070291///N-acylethanolamine metabolic process+++GO:0070292///N-acylphosphatidylethanolamine metabolic process 67112 67112 'Fgf22' mRNA 24 21 19 1.38 1.12 1.07 0.16 0.45 0.7 1.19 0.436666667 3 9 13 21.33333333 8.333333333 0.064217873 -1.359134256 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0008083///growth factor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration 67115 67115 'Rpl14' mRNA 3380 3524 3399 235.14 242.6 250.91 233.84 232.75 242.35 242.8833333 236.3133333 3852 3736 3857 3434.333333 3815 0.03374044 0.139453741 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006364///rRNA processing+++GO:0006412///translation+++GO:0042273///ribosomal large subunit biogenesis 67116 67116 'Cuedc2' mRNA 2913.25 2855.77 2807.1 142.56 138.82 146.26 164.14 162.23 152.27 142.5466667 159.5466667 3787.84 3658.34 3435.23 2858.706667 3627.136667 4.21E-07 0.33109865 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0043130///ubiquitin binding GO:0010936///negative regulation of macrophage cytokine production+++GO:1900016///negative regulation of cytokine production involved in inflammatory response 67117 67117 'Dynlt3' mRNA 2543 2643 2619 66.73 68.31 72.9 62.18 60.14 61.84 69.31333333 61.38666667 2725 2573 2623 2601.666667 2640.333333 0.930105089 0.008178335 05132///Salmonella infection "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0061673///mitotic spindle astral microtubule" GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division 67118 67118 'Bfar' mRNA 1116 1156 1213 21.28 21.41 24.62 23.84 22.02 22.48 22.43666667 22.78 1425 1290 1310 1161.666667 1341.666667 0.045785462 0.193075687 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0089720///caspase binding" "GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0097355///protein localization to heterochromatin+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response" 67119 67119 'Ccdc159' mRNA 140 171 122 5.38 6.48 4.97 3.34 3.66 3.87 5.61 3.623333333 100 107 112 144.3333333 106.3333333 0.066388891 -0.446902035 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67120 67120 'Ttc14' mRNA 2675.78 2808.65 2802.1 24.77 25.44 27.62 18.21 17.01 17.44 25.94333333 17.55333333 1961.53 1802.82 1831.37 2762.176667 1865.24 6.38E-16 -0.580310712 GO:0005575///cellular_component GO:0003676///nucleic acid binding+++GO:0005515///protein binding GO:0008150///biological_process 67121 67121 'Mastl' mRNA 17 17 25 0.19 0.2 0.31 1.01 1.08 0.98 0.233333333 1.023333333 101 106 90 19.66666667 99 4.97E-11 2.314578069 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032154///cleavage furrow GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0051721///protein phosphatase 2A binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007147///female meiosis II+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0035556///intracellular signal transduction+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:1904668///positive regulation of ubiquitin protein ligase activity 67122 67122 'Nrarp' mRNA 188 200 95 4.05 4.24 2.17 1.25 1.15 1.55 3.486666667 1.316666667 67 60 80 161 69 2.31E-05 -1.220260998 GO:0005575///cellular_component GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0022407///regulation of cell-cell adhesion+++GO:0032525///somite rostral/caudal axis specification+++GO:0045581///negative regulation of T cell differentiation+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902367///negative regulation of Notch signaling pathway involved in somitogenesis 67123 67123 'Ubap1' mRNA 1567.66 1638.59 1610.05 31.51 32.52 34.56 32.62 31.05 29.96 32.86333333 31.21 1821.12 1704.38 1633.55 1605.433333 1719.683333 0.351936314 0.086150777 GO:0000813///ESCRT I complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0043130///ubiquitin binding GO:0015031///protein transport+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 671232 671232 'Topaz1' mRNA 0 0 2 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0000239///pachytene+++GO:0006915///apoptotic process+++GO:0007128///meiotic prophase I+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0048137///spermatocyte division+++GO:0098781///ncRNA transcription+++GO:1901995///positive regulation of meiotic cell cycle phase transition 67125 67125 'Tspan31' mRNA 3416 3537 3349 130.17 132.85 135.25 161.31 176.69 174.49 132.7566667 170.83 4864 5199 5089 3434 5050.666667 4.12E-18 0.54578408 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 67126 67126 'Atp5e' mRNA 1940 1801 2308 458.39 428.55 579.49 450.03 521.79 532.94 488.81 501.5866667 2154 2417 2448 2016.333333 2339.666667 0.1031638 0.197466037 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)" "GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process 67127 67127 'Lce1a1' mRNA 2 1 1 0.2 0.1 0.11 0.09 0.45 0.09 0.136666667 0.21 1 5 1 1.333333333 2.333333333 0.739263611 0.812127052 GO:0008544///epidermis development+++GO:0031424///keratinization 67128 67128 'Ube2g1' mRNA 975 963 551 13.75 13.36 8.24 6.93 9.25 8.18 11.78333333 8.12 566 738 647 829.6666667 650.3333333 0.047716327 -0.348645881 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044257///cellular protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination 67130 67130 'Ndufa6' mRNA 1780 1761 1713 251.84 248.48 257.29 220.51 221.66 230 252.5366667 224.0566667 1776 1734 1784 1751.333333 1764.666667 0.998591786 -8.84E-04 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0006979///response to oxidative stress+++GO:0032981///mitochondrial respiratory chain complex I assembly 67134 67134 'Nop56' mRNA 1179 1204 1206 32.59 32.81 34.48 42.97 45.21 42.4 33.29333333 43.52666667 1733 1777 1649 1196.333333 1719.666667 3.96E-10 0.51107197 03008///Ribosome biogenesis in eukaryotes+++05017///Spinocerebellar ataxia GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0031428///box C/D snoRNP complex+++GO:0032040///small-subunit processome+++GO:0070761///pre-snoRNP complex GO:0003723///RNA binding+++GO:0030515///snoRNA binding+++GO:1990226///histone methyltransferase binding GO:0042254///ribosome biogenesis 67135 67135 'Bpifa5' mRNA 113 130 132 6.53 7.43 8.1 0.25 0.21 0.26 7.353333333 0.24 5 4 5 125 4.666666667 4.48E-23 -4.758024981 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0008289///lipid binding GO:0002395///immune response in nasopharyngeal-associated lymphoid tissue+++GO:0019731///antibacterial humoral response+++GO:0045087///innate immune response+++GO:0050828///regulation of liquid surface tension+++GO:0050891///multicellular organismal water homeostasis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1900229///negative regulation of single-species biofilm formation in or on host organism+++GO:1902305///regulation of sodium ion transmembrane transport 67136 67136 'Kbtbd4' mRNA 1031 1054 1017 23.88 24.08 24.79 16.18 18.39 16.95 24.25 17.17333333 808 899 821 1034 842.6666667 0.001978111 -0.306150572 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67138 67138 'Herc6' mRNA 322 341 251 3.25 3.39 2.69 6.32 5.88 5.86 3.11 6.02 721 655 647 304.6666667 674.3333333 5.41E-20 1.13846985 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0061630///ubiquitin protein ligase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002376///immune system process+++GO:0009617///response to bacterium+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 67139 67139 'Mis12' mRNA 566.86 633.83 631.74 10.67 11.82 12.35 12.27 13.29 13.13 11.61333333 12.89666667 747.71 798.87 765.86 610.81 770.8133333 0.00483948 0.323493804 "GO:0000444///MIS12/MIND type complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0003674///molecular_function GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051382///kinetochore assembly 67141 67141 'Fbxo5' mRNA 78 62 68.31 2.34 1.86 2.26 5.54 4.53 5.21 2.153333333 5.093333333 204 163 186.7 69.43666667 184.5666667 9.71E-10 1.396905937 04114///Oocyte meiosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043025///neuronal cell body+++GO:0072687///meiotic spindle GO:0005515///protein binding+++GO:0010997///anaphase-promoting complex binding+++GO:0019901///protein kinase binding+++GO:0030332///cyclin binding+++GO:0046872///metal ion binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0001556///oocyte maturation+++GO:0006275///regulation of DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0007088///regulation of mitotic nuclear division+++GO:0007346///regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016050///vesicle organization+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032876///negative regulation of DNA endoreduplication+++GO:0040020///regulation of meiotic nuclear division+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0045841///negative regulation of mitotic metaphase/anaphase transition+++GO:0046785///microtubule polymerization+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0060903///positive regulation of meiosis I+++GO:0070169///positive regulation of biomineral tissue development+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:1905322///positive regulation of mesenchymal stem cell migration+++GO:2000773///negative regulation of cellular senescence+++GO:2001021///negative regulation of response to DNA damage stimulus+++GO:2001224///positive regulation of neuron migration 67143 67143 'Ikzf5' mRNA 762.27 781.38 725.67 8.87 8.96 9.05 5.65 6.12 6.18 8.96 5.983333333 557.48 576.93 586.27 756.44 573.56 8.30E-05 -0.410444996 GO:0005634///nucleus+++GO:0032991///protein-containing complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II 67144 67144 'Lrrc40' mRNA 448 551 537 9.45 11.35 11.97 9.74 9.41 10.04 10.92333333 9.73 540 506 533 512 526.3333333 0.875265739 0.025956398 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0004722///protein serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction 67145 67145 'Tomm34' mRNA 2714 2733 2686 78.16 77.48 82.31 50.47 47.62 48.88 79.31666667 48.99 2004 1828 1868 2711 1900 1.01E-14 -0.52579759 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0031072///heat shock protein binding GO:0006626///protein targeting to mitochondrion 67148 67148 'Ramac' mRNA 2257.82 2302.12 2245.21 94.53 95.1 99.73 74.03 73.34 72.41 96.45333333 73.26 2030.74 1962.64 1921.35 2268.383333 1971.576667 0.002821534 -0.214883564 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005845///mRNA cap binding complex+++GO:0031533///mRNA cap methyltransferase complex GO:0003723///RNA binding+++GO:0008047///enzyme activator activity GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0032259///methylation+++GO:0036031///recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex+++GO:0050790///regulation of catalytic activity+++GO:0106005///RNA 5'-cap (guanine-N7)-methylation 67149 67149 'Nkain1' mRNA 3 4 3 0.07 0.09 0.07 0.58 0.59 0.78 0.076666667 0.65 29 29 39 3.333333333 32.33333333 4.27E-06 3.269218501 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0051117///ATPase binding GO:0002028///regulation of sodium ion transport 67150 67150 'Rnf141' mRNA 1482.12 1551.77 1484.87 23.88 26.1 24.27 31.28 25.96 31.04 24.75 29.42666667 1907.97 1641.92 1815.19 1506.253333 1788.36 0.004277564 0.234669336 GO:0005575///cellular_component+++GO:0016020///membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0051865///protein autoubiquitination" 67151 67151 'Psmd9' mRNA 999 1066 899 21.41 22.49 20.44 20.6 21.06 21.47 21.44666667 21.04333333 1106 1104 1116 988 1108.666667 0.097326464 0.157085879 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008540///proteasome regulatory particle, base subcomplex" GO:0003674///molecular_function+++GO:0003713///transcription coactivator activity+++GO:0008022///protein C-terminus binding+++GO:0043425///bHLH transcription factor binding "GO:0032024///positive regulation of insulin secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046676///negative regulation of insulin secretion+++GO:0070682///proteasome regulatory particle assembly+++GO:0097050///type B pancreatic cell apoptotic process" 67153 67153 'Rnaseh2b' mRNA 103 118 108 4.06 4.59 4.52 8.45 9.01 8.95 4.39 8.803333333 246 256 252 109.6666667 251.3333333 1.80E-10 1.18559332 03030///DNA replication GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032299///ribonuclease H2 complex GO:0001701///in utero embryonic development+++GO:0006401///RNA catabolic process+++GO:0009259///ribonucleotide metabolic process+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0010629///negative regulation of gene expression+++GO:0048146///positive regulation of fibroblast proliferation+++GO:2000001///regulation of DNA damage checkpoint 671535 671535 'Parp10' mRNA 498 532 451 8.23 8.6 7.9 13.97 13.41 13.92 8.243333333 13.76666667 978 916 944 493.6666667 946 2.24E-21 0.928344596 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol "GO:0003714///transcription corepressor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0006281///DNA repair+++GO:0006471///protein ADP-ribosylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010629///negative regulation of gene expression+++GO:0010847///regulation of chromatin assembly+++GO:0019985///translesion synthesis+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045071///negative regulation of viral genome replication+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:1900045///negative regulation of protein K63-linked ubiquitination" 67154 67154 'Mtdh' mRNA 1997.09 1870.57 1977.02 22.11 20.34 23.19 23.77 22.03 22.54 21.88 22.78 2474.14 2239.58 2269.9 1948.226667 2327.873333 0.002229399 0.242517574 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0031965///nuclear membrane+++GO:0046581///intercellular canaliculus+++GO:0048471///perinuclear region of cytoplasm GO:0001085///RNA polymerase II transcription factor binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0051059///NF-kappaB binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010508///positive regulation of autophagy+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045766///positive regulation of angiogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070830///bicellular tight junction assembly" 67155 67155 'Smarca2' mRNA 3571 3492 3239 32.56 31.11 34.28 26.9 25.51 26.49 32.65 26.3 2875 2672 2788 3434 2778.333333 1.83E-07 -0.316796264 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0000166///nucleotide binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042393///histone binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007286///spermatid development+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0030308///negative regulation of cell growth+++GO:0035887///aortic smooth muscle cell differentiation+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061484///hematopoietic stem cell homeostasis" 67157 67157 '2610301B20Rik' mRNA 1200 1402 1258 32.02 36.85 35.62 18.96 19.97 18.94 34.83 19.29 817 840 790 1286.666667 815.6666667 5.59E-13 -0.668633184 GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0097546///ciliary base GO:0003674///molecular_function GO:0008594///photoreceptor cell morphogenesis 67158 67158 'Sft2d3' mRNA 636 662 328 12.49 12.8 6.83 4.11 7.67 6.03 10.70666667 5.936666667 241 439 342 542 340.6666667 0.130565544 -0.660657583 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 67160 67160 'Eef1g' mRNA 4530 4492 4302 169.97 166.21 171.25 214.35 209.92 219.56 169.1433333 214.61 6563 6272 6504 4441.333333 6446.333333 5.02E-23 0.525745721 05134///Legionellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0003746///translation elongation factor activity GO:0006412///translation+++GO:0006414///translational elongation+++GO:0006749///glutathione metabolic process+++GO:0009615///response to virus 67161 67161 'Sclt1' mRNA 282 340 145 5.13 6.13 2.97 1.8 2.45 2.35 4.743333333 2.2 110 148 144 255.6666667 134 3.93E-04 -0.925059981 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0071439///clathrin complex+++GO:0097539///ciliary transition fiber GO:0008022///protein C-terminus binding+++GO:0017080///sodium channel regulator activity+++GO:0030276///clathrin binding GO:0045162///clustering of voltage-gated sodium channels+++GO:0060271///cilium assembly 67163 67163 'Ccdc47' mRNA 3838 3727 4012 63.98 61.02 70.95 52.2 50.17 52.19 65.31666667 51.52 3604 3389 3486 3859 3493 0.038539777 -0.158484229 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030867///rough endoplasmic reticulum membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0043022///ribosome binding+++GO:0044183///protein binding involved in protein folding GO:0006457///protein folding+++GO:0006983///ER overload response+++GO:0007029///endoplasmic reticulum organization+++GO:0009790///embryo development+++GO:0009791///post-embryonic development+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0036503///ERAD pathway+++GO:0045048///protein insertion into ER membrane+++GO:0055074///calcium ion homeostasis 67164 67164 'Lipt2' mRNA 153 172 147 7.61 8.45 7.76 5.98 6.75 5.24 7.94 5.99 138 152 117 157.3333333 135.6666667 0.367068824 -0.223213468 00785///Lipoic acid metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion "GO:0005515///protein binding+++GO:0016415///octanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016874///ligase activity+++GO:0033819///lipoyl(octanoyl) transferase activity+++GO:0102555///octanoyl transferase activity (acting on glycine-cleavage complex H protein)" GO:0006464///cellular protein modification process+++GO:0009249///protein lipoylation+++GO:2000376///positive regulation of oxygen metabolic process 671650 671650 'Gm20783' mRNA 0 2 0 0 0.04 0 0.02 0.03 0.02 0.013333333 0.023333333 1 2 1 0.666666667 1.333333333 0.763286588 1.02774447 67166 67166 'Arl8b' mRNA 2404 2373 2346 45.18 43.89 46.77 58.51 53.1 53.93 45.28 55.18 3582 3175 3197 2374.333333 3318 4.06E-12 0.469499872 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0051233///spindle midzone+++GO:0101004///cytolytic granule membrane+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding GO:0001778///plasma membrane repair+++GO:0002505///antigen processing and presentation of polysaccharide antigen via MHC class II+++GO:0002747///antigen processing and presentation following phagocytosis+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0032418///lysosome localization+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0046754///viral exocytosis+++GO:0051301///cell division+++GO:0061909///autophagosome-lysosome fusion+++GO:0090117///endosome to lysosome transport of low-density lipoprotein particle+++GO:0090385///phagosome-lysosome fusion+++GO:1902774///late endosome to lysosome transport+++GO:1990927///calcium ion regulated lysosome exocytosis 67168 67168 'Lpar6' mRNA 384 398 382 8.68 8.86 9.16 13.16 15.27 13.05 8.9 13.82666667 670 759 643 388 690.6666667 9.60E-12 0.821223444 04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0070915///lysophosphatidic acid receptor activity GO:0001835///blastocyst hatching+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 67169 67169 'Nradd' mRNA 221 231 249 11.73 12.11 14.03 14.9 16.13 18.23 12.62333333 16.42 322 340 381 233.6666667 347.6666667 5.71E-04 0.559898173 GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0032589///neuron projection membrane+++GO:0044298///cell body membrane GO:0005035///death receptor activity+++GO:0005166///neurotrophin p75 receptor binding+++GO:0005515///protein binding+++GO:0015026///coreceptor activity+++GO:0048406///nerve growth factor binding GO:0001701///in utero embryonic development+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0007420///brain development+++GO:0010942///positive regulation of cell death 67171 67171 'Dram2' mRNA 1249.1 1337.04 1271.12 26.97 28.68 30.22 33.47 33.81 33.48 28.62333333 33.58666667 1685.76 1714.23 1638.49 1285.753333 1679.493333 2.77E-06 0.373417893 GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0007601///visual perception+++GO:0010506///regulation of autophagy+++GO:0045494///photoreceptor cell maintenance 67177 67177 'Cdt1' mRNA 77 58 37 1.98 1.47 1.01 6.89 7.13 6.84 1.486666667 6.953333333 308 311 296 57.33333333 305 9.77E-28 2.407176106 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body" GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0070182///DNA polymerase binding GO:0000076///DNA replication checkpoint+++GO:0000278///mitotic cell cycle+++GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0030174///regulation of DNA-dependent DNA replication initiation+++GO:0031334///positive regulation of protein complex assembly+++GO:0033044///regulation of chromosome organization+++GO:0033262///regulation of nuclear cell cycle DNA replication+++GO:0035563///positive regulation of chromatin binding+++GO:0045740///positive regulation of DNA replication+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051383///kinetochore organization+++GO:0071163///DNA replication preinitiation complex assembly+++GO:0072708///response to sorbitol+++GO:1902426///deactivation of mitotic spindle assembly checkpoint+++GO:1902595///regulation of DNA replication origin binding+++GO:1905341///negative regulation of protein localization to kinetochore+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:2000105///positive regulation of DNA-dependent DNA replication 67178 67178 'Zmat5' mRNA 503.39 532.29 521.41 40.19 42.53 45.6 45.34 46.4 42.92 42.77333333 44.88666667 631.52 641.08 587.27 519.03 619.9566667 0.042776249 0.244426657 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 67179 67179 'Ccdc25' mRNA 637 676 584 16.11 16.83 15.66 27.31 25.02 24.17 16.2 25.5 1242 1111 1064 632.3333333 1139 7.48E-19 0.838147551 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding GO:2000147///positive regulation of cell motility 67180 67180 'Yipf5' mRNA 1236 1385 1270 29.75 32.83 32.43 38.81 38.87 38.16 31.67 38.61333333 1854 1813 1765 1297 1810.666667 1.84E-09 0.469775956 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042175///nuclear outer membrane-endoplasmic reticulum membrane network+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport 67181 67181 'Ctdnep1' mRNA 286 327 230 10.35 11.67 8.83 12.85 11.85 13.32 10.28333333 12.67333333 408 366.93 409 281 394.6433333 0.001608555 0.481918399 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0071595///Nem1-Spo7 phosphatase complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0006998///nuclear envelope organization+++GO:0007276///gamete generation+++GO:0007498///mesoderm development+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0034504///protein localization to nucleus+++GO:0090263///positive regulation of canonical Wnt signaling pathway 67182 67182 'Pdzk1ip1' mRNA 101 97 80 8.54 8.24 7.2 7.38 9.14 7.41 7.993333333 7.976666667 97 118 97 92.66666667 104 0.622266873 0.159680716 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67184 67184 'Ndufa13' mRNA 3700.36 3565.52 3788.14 399 381.24 433.67 357.67 441.07 388.44 404.6366667 395.7266667 3782.99 4545.82 3972.45 3684.673333 4100.42 0.139175801 0.142002631 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0070469///respiratory chain GO:0003954///NADH dehydrogenase activity+++GO:0005524///ATP binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity "GO:0006915///apoptotic process+++GO:0022900///electron transport chain+++GO:0030308///negative regulation of cell growth+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0035458///cellular response to interferon-beta+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071300///cellular response to retinoic acid+++GO:0072593///reactive oxygen species metabolic process+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 67186 67186 'Rplp2' mRNA 1328.04 1203.17 1445.99 262.74 238.98 303.37 307.08 352.61 343.38 268.3633333 334.3566667 1760.27 1958.94 1891.87 1325.733333 1870.36 2.85E-06 0.481394162 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0002182///cytoplasmic translational elongation+++GO:0006414///translational elongation 67187 67187 'Zmynd19' mRNA 24 23 25 0.49 0.46 0.54 0.44 0.33 0.59 0.496666667 0.453333333 25 18 32 24 25 0.949006166 0.043988516 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 671917 671917 'LOC671917' mRNA 1.33 2.45 1.23 0.06 0.11 0.06 0.62 0.31 0.44 0.076666667 0.456666667 15.23 7.46 10.5 1.67 11.06333333 0.015395774 2.987069047 67196 67196 'Ube2t' mRNA 16 13 4 0.95 0.7 0.29 4.81 4.97 3.51 0.646666667 4.43 90 92 63 11 81.66666667 1.18E-10 2.892074777 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0035519///protein K29-linked ubiquitination+++GO:0044314///protein K27-linked ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination 67197 67197 'Zcrb1' mRNA 655 686 669 49.25 50.99 53.42 47.06 54.87 51.37 51.22 51.1 722 818 760 670 766.6666667 0.121673337 0.183343761 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 67198 67198 'Spats2l' mRNA 914 845 952 12.24 10.96 13.65 7.81 7.26 7.2 12.28333333 7.423333333 658 600 599 903.6666667 619 2.60E-07 -0.561253836 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0008150///biological_process 67199 67199 'Pfdn1' mRNA 906 928 860 52.85 53.51 53.23 66.22 69.12 62.56 53.19666667 65.96666667 1302 1325 1189 898 1272 2.39E-08 0.49143004 GO:0005737///cytoplasm+++GO:0016272///prefoldin complex GO:0001540///amyloid-beta binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0021537///telencephalon development+++GO:0021549///cerebellum development+++GO:0030036///actin cytoskeleton organization+++GO:0042113///B cell activation+++GO:1905907///negative regulation of amyloid fibril formation 67200 67200 'Ccdc77' mRNA 290.27 235.47 236.32 6.06 4.95 5.4 3.98 3.65 3.18 5.47 3.603333333 214.87 190.81 165.32 254.02 190.3333333 0.023013191 -0.431504175 GO:0005813///centrosome GO:0003674///molecular_function GO:0008150///biological_process 67201 67201 'Glod4' mRNA 2946.03 2987.25 2950.02 64.84 64.76 68.97 55.16 55.93 52.9 66.19 54.66333333 2876.53 2850.45 2672.87 2961.1 2799.95 0.224735846 -0.093535362 GO:0005739///mitochondrion 67203 67203 'Nde1' mRNA 1920 2025 1934 47.72 49.25 51.2 46.38 43.18 43.92 49.39 44.49333333 2160 1956 1976 1959.666667 2030.666667 0.691484814 0.038592719 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0031616///spindle pole centrosome+++GO:0032154///cleavage furrow+++GO:0045202///synapse" GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding GO:0000132///establishment of mitotic spindle orientation+++GO:0001764///neuron migration+++GO:0007020///microtubule nucleation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007100///mitotic centrosome separation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007405///neuroblast proliferation+++GO:0016477///cell migration+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030900///forebrain development+++GO:0031023///microtubule organizing center organization+++GO:0047496///vesicle transport along microtubule+++GO:0051298///centrosome duplication+++GO:0051301///cell division+++GO:0051303///establishment of chromosome localization+++GO:0051642///centrosome localization+++GO:2000574///regulation of microtubule motor activity 67204 67204 'Eif2s2' mRNA 1379 1451 1478 30.56 31.66 34.74 41.56 42.46 41.83 32.32 41.95 2157 2152 2102 1436 2137 8.67E-13 0.560248581 GO:0005737///cytoplasm+++GO:0005850///eukaryotic translation initiation factor 2 complex GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0031369///translation initiation factor binding+++GO:0046872///metal ion binding GO:0001701///in utero embryonic development+++GO:0001731///formation of translation preinitiation complex+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002176///male germ cell proliferation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0008584///male gonad development 67205 67205 'Utp11' mRNA 1002.57 947.81 920.4 40.07 38.91 40.25 40.4 46.74 42.53 39.74333333 43.22333333 1463.12 1658.86 1559.27 956.9266667 1560.416667 6.71E-15 0.695869589 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032040///small-subunit processome GO:0006364///rRNA processing+++GO:0007399///nervous system development+++GO:0043065///positive regulation of apoptotic process 67207 67207 'Lsm1' mRNA 632 716 624 14.94 16.66 15.66 16.66 15.16 14.93 15.75333333 15.58333333 810 720 703 657.3333333 744.3333333 0.151141538 0.167870721 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:1990124///messenger ribonucleoprotein complex+++GO:1990726///Lsm1-7-Pat1 complex GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0019827///stem cell population maintenance+++GO:0045665///negative regulation of neuron differentiation+++GO:0071044///histone mRNA catabolic process 67210 67210 'Gatad1' mRNA 1060 945 1159 23.15 20.32 26.85 24 23.57 23.85 23.44 23.80666667 1264 1212 1216 1054.666667 1230.666667 0.073555475 0.205913749 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated" 67211 67211 'Armc10' mRNA 536 558 479 14.46 14.83 13.71 13.07 13.09 14.72 14.33333333 13.62666667 557 544 607 524.3333333 569.3333333 0.4244333 0.109409484 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0002039///p53 binding+++GO:0050692///DBD domain binding GO:0040008///regulation of growth+++GO:0040010///positive regulation of growth rate+++GO:0043066///negative regulation of apoptotic process+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 67212 67212 'Mrpl55' mRNA 623 628 591 41.99 42.08 42.49 40.55 41.7 42.87 42.18666667 41.70666667 687 687 701 614 691.6666667 0.158015687 0.160839441 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 67213 67213 'Cmtm6' mRNA 3228 3284 3198 52.57 52.59 55.22 52.92 51.26 51.24 53.46 51.80666667 3742 3539 3508 3236.666667 3596.333333 0.034610169 0.139453815 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane GO:0003674///molecular_function GO:0015031///protein transport+++GO:0031647///regulation of protein stability+++GO:0032456///endocytic recycling 67216 67216 'Mboat2' mRNA 1384 1484 1397 17.47 19.76 18.74 17.91 16.54 16.57 18.65666667 17.00666667 1394 1301 1271.24 1421.666667 1322.08 0.196288359 -0.117147863 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0030258///lipid modification+++GO:0032330///regulation of chondrocyte differentiation+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling 67217 67217 'L3hypdh' mRNA 199 259 246 5.68 6.92 7.43 7.94 8.57 7.54 6.676666667 8.016666667 306 309 288 234.6666667 301 0.05129585 0.3460652 00330///Arginine and proline metabolism GO:0005575///cellular_component GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0018112///proline racemase activity+++GO:0050346///trans-L-3-hydroxyproline dehydratase activity 67219 67219 'Med18' mRNA 160 140 114 5.55 4.79 4.19 4.59 4.24 5.02 4.843333333 4.616666667 152 137 161 138 150 0.691952415 0.112476083 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006369///termination of RNA polymerase II transcription+++GO:0016567///protein ubiquitination 67220 67220 'Plekho1' mRNA 336 315 259 14.71 13.59 12.02 23.6 24.66 22.58 13.44 23.61333333 620 632 574 303.3333333 608.6666667 3.05E-15 0.996742772 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0036195///muscle cell projection membrane GO:0005515///protein binding GO:0007520///myoblast fusion+++GO:0008360///regulation of cell shape+++GO:0051451///myoblast migration+++GO:0072673///lamellipodium morphogenesis+++GO:1901739///regulation of myoblast fusion 67222 67222 'Srfbp1' mRNA 280 266 295 5.84 5.46 6.53 7.58 6.13 5.28 5.943333333 6.33 418 330 282 280.3333333 343.3333333 0.140284555 0.275487283 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0030490///maturation of SSU-rRNA 67223 67223 'Rrp15' mRNA 232 247 215 11.72 12.32 11.53 18.23 18.91 15.3 11.85666667 17.48 414 419 336 231.3333333 389.6666667 1.28E-06 0.742092134 "GO:0030687///preribosome, large subunit precursor" GO:0003674///molecular_function GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing 67224 67224 'Med29' mRNA 599.28 647.85 649.15 15.65 16.67 17.99 18.43 16.67 17.9 16.77 17.66666667 811.32 716.52 762.67 632.0933333 763.5033333 0.02201284 0.258516864 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding GO:0006357///regulation of transcription by RNA polymerase II 67225 67225 'Rnpc3' mRNA 1611 1676 1627 26.86 27.06 27.7 12.34 13.16 11.75 27.20666667 12.41666667 801 824 724 1638 783 3.26E-35 -1.076975068 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005689///U12-type spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0030626///U12 snRNA binding+++GO:0097157///pre-mRNA intronic binding "GO:0000398///mRNA splicing, via spliceosome" 67226 67226 'Tmem19' mRNA 1043.08 1130.11 1068.2 16.5 17.27 17.13 16.88 17.71 16.49 16.96666667 17.02666667 1228.85 1247.7 1130.29 1080.463333 1202.28 0.151859265 0.141784324 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67228 67228 'Dph7' mRNA 522 529 580 17.4 17.67 20.54 13.83 12.35 13.81 18.53666667 13.33 471 408 452 543.6666667 443.6666667 0.021080943 -0.308912261 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0061685///diphthine methylesterase activity GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine 67229 67229 'Prpf18' mRNA 1385.03 1432.59 1340.08 21.02 21.39 21.57 15.87 16.04 15.55 21.32666667 15.82 1201 1185.52 1139.66 1385.9 1175.393333 0.002449958 -0.249277651 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071021///U2-type post-spliceosomal complex GO:0000350///generation of catalytic spliceosome for second transesterification step+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0071048///nuclear retention of unspliced pre-mRNA at the site of transcription 67230 67230 'Zfp329' mRNA 570 591 621 5.74 5.44 6.39 4.42 4.22 4.22 5.856666667 4.286666667 553 458 485.33 594 498.7766667 0.039129001 -0.267816764 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 67231 67231 'Tbc1d20' mRNA 1409 1334 497 22.69 21.14 8.49 12.26 14.34 16.24 17.44 14.28 876 1001 1124 1080 1000.333333 0.863357859 -0.099590079 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0031965///nuclear membrane GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0001675///acrosome assembly+++GO:0002088///lens development in camera-type eye+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0019068///virion assembly+++GO:0034389///lipid droplet organization+++GO:0043010///camera-type eye development+++GO:0043547///positive regulation of GTPase activity+++GO:0044829///positive regulation by host of viral genome replication+++GO:0046726///positive regulation by virus of viral protein levels in host cell+++GO:0070309///lens fiber cell morphogenesis+++GO:0072520///seminiferous tubule development+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport 67235 67235 'Zkscan14' mRNA 417 442 381 12.06 12.53 11.81 9.63 7.66 7.06 12.13333333 8.116666667 385 299 273 413.3333333 319 0.013798591 -0.385911618 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 67236 67236 'Cinp' mRNA 542 543 584 15.13 14.95 17.25 16.34 17.96 17.19 15.77666667 17.16333333 674 723 686 556.3333333 694.3333333 0.010534738 0.306345884 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008150///biological_process+++GO:0051301///cell division 67238 67238 'Fam220a' mRNA 179 194 117 4.55 4.77 3.18 2.87 2.78 2.62 4.166666667 2.756666667 130 123 117 163.3333333 123.3333333 0.096442826 -0.408516098 GO:0005634///nucleus GO:0005515///protein binding+++GO:0097677///STAT family protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006470///protein dephosphorylation+++GO:0032092///positive regulation of protein binding 67239 67239 'Rpf2' mRNA 300 378 353 11.77 14.68 14.69 16.5 18.3 15.73 13.71333333 16.84333333 482 519 445 343.6666667 482 0.001088058 0.475951288 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008097///5S rRNA binding+++GO:0019843///rRNA binding" "GO:0000027///ribosomal large subunit assembly+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000470///maturation of LSU-rRNA+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1902570///protein localization to nucleolus" 67241 67241 'Smc6' mRNA 874 946 892 17.29 19.34 18.82 22.41 23.79 21.74 18.48333333 22.64666667 1261 1260 1156 904 1225.666667 2.21E-06 0.427362777 "GO:0000775///chromosome, centromeric region+++GO:0000781///chromosome, telomeric region+++GO:0000803///sex chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0030915///Smc5-Smc6 complex+++GO:0035061///interchromatin granule+++GO:0035861///site of double-strand break+++GO:0097431///mitotic spindle pole" GO:0000166///nucleotide binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0036121///double-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051984///positive regulation of chromosome segregation+++GO:0090398///cellular senescence 67242 67242 'Gemin6' mRNA 173 209 193 9.56 11.41 11.31 14.9 14.43 11.31 10.76 13.54666667 308.99 292 226.98 191.6666667 275.99 0.006935817 0.509614025 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0097504///Gemini of coiled bodies GO:0005515///protein binding GO:0000245///spliceosomal complex assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 67245 67245 'Peli1' mRNA 1514 1679 1635 23.66 25.83 27.12 19.3 20.75 18.04 25.53666667 19.36333333 1421 1490 1287 1609.333333 1399.333333 0.025874867 -0.214275617 GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005634///nucleus GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0001819///positive regulation of cytokine production+++GO:0008063///Toll signaling pathway+++GO:0008592///regulation of Toll signaling pathway+++GO:0016567///protein ubiquitination+++GO:0030890///positive regulation of B cell proliferation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032496///response to lipopolysaccharide+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0042130///negative regulation of T cell proliferation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043331///response to dsRNA+++GO:0050868///negative regulation of T cell activation+++GO:0050871///positive regulation of B cell activation+++GO:0060546///negative regulation of necroptotic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination 67246 67246 'Resf1' mRNA 1707 1892 1749.28 14.77 16.07 16.02 20.64 18.37 18.72 15.62 19.24333333 2726 2365.56 2393.31 1782.76 2494.956667 5.81E-10 0.471928697 GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus GO:1990226///histone methyltransferase binding GO:0009617///response to bacterium+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0090309///positive regulation of methylation-dependent chromatin silencing 67247 67247 'Mtarc2' mRNA 2631 2638 2602 86.16 86.1 93.47 89.31 92.94 82.04 88.57666667 88.09666667 3029 3025 2725 2623.666667 2926.333333 0.058891557 0.145104016 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome+++GO:0016020///membrane "GO:0003824///catalytic activity+++GO:0008940///nitrate reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016661///oxidoreductase activity, acting on other nitrogenous compounds as donors+++GO:0030151///molybdenum ion binding+++GO:0030170///pyridoxal phosphate binding+++GO:0043546///molybdopterin cofactor binding+++GO:0098809///nitrite reductase activity" GO:0006809///nitric oxide biosynthetic process+++GO:0042126///nitrate metabolic process+++GO:0070458///cellular detoxification of nitrogen compound 67248 67248 'Rpl39' mRNA 675 624 889 146.16 135.81 204.49 202.25 214.98 246.85 162.1533333 221.36 1058 1089 1240 729.3333333 1129 2.03E-05 0.610262327 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0002181///cytoplasmic translation+++GO:0002227///innate immune response in mucosa+++GO:0006412///translation+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 67249 67249 'Tbc1d19' mRNA 1030 1058 1110 17.67 17.67 20.6 13.3 13.64 13.16 18.64666667 13.36666667 884 874 840 1066 866 0.001580975 -0.313707178 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 672511 672511 'Rnf213' mRNA 1015 1064 919 3.1 3.22 2.99 6.99 6.27 7.06 3.103333333 6.773333333 2615 2293 2555 999.3333333 2487.666667 1.91E-67 1.305132079 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0051260///protein homooligomerization+++GO:0051865///protein autoubiquitination+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway 67252 67252 'Cap2' mRNA 252 225 257 4.01 3.72 4.74 0.64 0.81 0.87 4.156666667 0.773333333 42 50 53 244.6666667 48.33333333 2.21E-25 -2.353272082 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane GO:0003779///actin binding+++GO:0008179///adenylate cyclase binding+++GO:0042802///identical protein binding GO:0000902///cell morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0019933///cAMP-mediated signaling+++GO:0045761///regulation of adenylate cyclase activity 67254 67254 'Bmerb1' mRNA 21.82 24.01 35.04 0.45 0.4 0.72 0.17 0.32 0.32 0.523333333 0.27 11.1 20.62 22 26.95666667 17.90666667 0.33793839 -0.611735206 GO:0015630///microtubule cytoskeleton GO:0005515///protein binding GO:0007026///negative regulation of microtubule depolymerization+++GO:0021822///negative regulation of cell motility involved in cerebral cortex radial glia guided migration 67255 67255 'Zfp422' mRNA 1196.82 1245.55 1191.83 26.46 27.54 28.06 22.16 22.67 20.84 27.35333333 21.89 1146.8 1132.83 1037.86 1211.4 1105.83 0.13192254 -0.143750352 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042476///odontogenesis" 67260 67260 'Cers4' mRNA 1092.12 1167.36 1220.51 14.99 15.85 17.76 13.77 13.32 13.09 16.2 13.39333333 1140.26 1055.19 1038.81 1159.996667 1078.086667 0.2718842 -0.120635956 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process 67263 67263 'Zswim6' mRNA 238 220 182 2.32 2.11 1.88 1.85 1.48 1.43 2.103333333 1.586666667 218 171 164 213.3333333 184.3333333 0.312052348 -0.220905384 GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0032420///stereocilium GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0007399///nervous system development+++GO:0021773///striatal medium spiny neuron differentiation+++GO:0048812///neuron projection morphogenesis+++GO:1902667///regulation of axon guidance+++GO:2001222///regulation of neuron migration 67264 67264 'Ndufb8' mRNA 4210 4066 4006 441 421.64 445.15 474.65 521.75 462.39 435.93 486.2633333 5268 5578 4942 4094 5262.666667 2.30E-07 0.350796717 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function+++GO:0003954///NADH dehydrogenase activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly" 67266 67266 'Dipk1a' mRNA 1680.43 1932.06 1837.46 34.13 38.62 39.59 36.71 37.35 34.76 37.44666667 36.27333333 2079.1 2066.06 1906.09 1816.65 2017.083333 0.131043406 0.138513448 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process 67267 67267 'Uqcc2' mRNA 863 807 890 160.36 150.46 175.85 191.07 212.13 205.66 162.2233333 202.9533333 1168 1255 1207 853.3333333 1210 7.75E-07 0.490483845 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0042645///mitochondrial nucleoid GO:0003674///molecular_function GO:0002082///regulation of oxidative phosphorylation+++GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0050796///regulation of insulin secretion+++GO:0070131///positive regulation of mitochondrial translation+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:2001014///regulation of skeletal muscle cell differentiation 67268 67268 'Myl12a' mRNA 3297.64 3324.7 3330.7 118.44 118.19 126.76 206.67 209.38 203.31 121.13 206.4533333 6553.51 6519.1 6260.41 3317.68 6444.34 3.82E-56 0.945366731 04360///Axon guidance+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection GO:0001725///stress fiber+++GO:0016460///myosin II complex+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0099738///cell cortex region GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0035254///glutamate receptor binding GO:0008360///regulation of cell shape+++GO:0072659///protein localization to plasma membrane 67269 67269 'Agtpbp1' mRNA 347 399 338 3.6 4.19 3.89 3.94 4.17 4.33 3.893333333 4.146666667 431 411 409 361.3333333 417 0.17660293 0.196450437 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0043231///intracellular membrane-bounded organelle+++GO:1904115///axon cytoplasm GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001754///eye photoreceptor cell differentiation+++GO:0006508///proteolysis+++GO:0007005///mitochondrion organization+++GO:0007628///adult walking behavior+++GO:0008285///negative regulation of cell proliferation+++GO:0021549///cerebellum development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021772///olfactory bulb development+++GO:0021954///central nervous system neuron development+++GO:0035608///protein deglutamylation+++GO:0035609///C-terminal protein deglutamylation+++GO:0035610///protein side chain deglutamylation+++GO:0042133///neurotransmitter metabolic process+++GO:0050905///neuromuscular process+++GO:0060041///retina development in camera-type eye+++GO:0098930///axonal transport+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0098958///retrograde axonal transport of mitochondrion+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 67270 67270 'Mrpl42' mRNA 1491 1527 1482 161.79 164.34 170.7 175.83 205.43 179.11 165.61 186.79 1854 2108 1819 1500 1927 6.94E-05 0.350485936 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0005886///plasma membrane GO:0008150///biological_process 67272 67272 'Cmtm5' mRNA 1633 1632 1608 121.23 119.82 127.2 42.68 46.87 49.16 122.75 46.23666667 660 706 728 1624.333333 698 4.15E-45 -1.230068575 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005125///cytokine activity GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0045662///negative regulation of myoblast differentiation 67273 67273 'Ndufa10' mRNA 2278 2301 2277 106.88 107.29 112.77 97.42 95.49 95.76 108.98 96.22333333 2376 2309 2293 2285.333333 2326 0.885166756 0.012887269 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005759///mitochondrial matrix+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain GO:0008137///NADH dehydrogenase (ubiquinone) activity "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly" 67276 67276 'Eri1' mRNA 300 347 307 3.51 4 3.9 6.91 7.77 8.03 3.803333333 7.57 660 733 745 318 712.6666667 3.06E-21 1.154545454 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071204///histone pre-mRNA 3'end processing complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding+++GO:0071207///histone pre-mRNA stem-loop binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000738///DNA catabolic process, exonucleolytic+++GO:0006364///rRNA processing+++GO:0031047///gene silencing by RNA+++GO:0031125///rRNA 3'-end processing+++GO:0071044///histone mRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 67278 67278 'Pagr1a' mRNA 797 734 753 33.67 30.6 33.75 35.35 35.82 33.66 32.67333333 34.94333333 961 950 885 761.3333333 932 0.006020353 0.279377751 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex GO:0005515///protein binding+++GO:0030331///estrogen receptor binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048304///positive regulation of isotype switching to IgG isotypes+++GO:0051568///histone H3-K4 methylation+++GO:0060717///chorion development+++GO:0071557///histone H3-K27 demethylation+++GO:1902749///regulation of cell cycle G2/M phase transition+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:2001022///positive regulation of response to DNA damage stimulus 67279 67279 'Med31' mRNA 719.3 693.75 731.69 38.3 36.49 41.34 29.86 31.67 30.3 38.71 30.61 643.46 665.36 631.17 714.9133333 646.6633333 0.191562067 -0.157332718 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0060173///limb development" 67281 67281 'Rpl37' mRNA 927.67 980.79 1263.91 71.09 74.43 102.78 68.53 69.65 85.15 82.76666667 74.44333333 1024.23 1014.04 1229.17 1057.456667 1089.146667 0.891671405 0.024108521 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019838///growth factor binding+++GO:0019843///rRNA binding+++GO:0046872///metal ion binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0006412///translation+++GO:1901798///positive regulation of signal transduction by p53 class mediator 67282 67282 'Washc3' mRNA 687 659 617 42.86 40.23 40.61 56.56 54.79 59.14 41.23333333 56.83 1044 980 1050 654.3333333 1024.666667 6.52E-12 0.636059456 04144///Endocytosis+++04212///Longevity regulating pathway - worm GO:0005768///endosome+++GO:0005769///early endosome+++GO:0071203///WASH complex GO:0003674///molecular_function GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0030041///actin filament polymerization 67283 67283 'Slc25a19' mRNA 1190 1190 1112 24.39 24.42 24.31 13.84 16.2 15.33 24.37333333 15.12333333 742 843 791 1164 792 1.96E-09 -0.565360336 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0015234///thiamine transmembrane transporter activity GO:0030974///thiamine pyrophosphate transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071934///thiamine transmembrane transport 67285 67285 'Cwc27' mRNA 558 500.38 534 16.16 14.35 16.22 15.9 15.09 13.6 15.57666667 14.86333333 645 581 522 530.7933333 582.6666667 0.410100448 0.120765099 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 67286 67286 'Ift22' mRNA 1491 1423 1520 73.5 66.06 80.57 39.18 40.71 45 73.37666667 41.63 806 822 837 1478 821.6666667 1.46E-21 -0.86045066 GO:0005813///centrosome+++GO:0005929///cilium+++GO:0012505///endomembrane system+++GO:0030992///intraciliary transport particle B+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0042073///intraciliary transport 67287 67287 'Parp6' mRNA 1981 1958 1540 39.12 38 32.83 9.12 10.32 10.59 36.65 10.01 534 590 619 1826.333333 581 5.94E-63 -1.658144258 GO:0005622///intracellular "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity" GO:0006471///protein ADP-ribosylation+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0070213///protein auto-ADP-ribosylation 67288 67288 'Srek1ip1' mRNA 437 386 460 14.22 12.38 15.88 11.81 11.26 12.5 14.16 11.85666667 417 388 427 427.6666667 410.6666667 0.688266363 -0.074171675 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 67290 67290 '3110040N11Rik' mRNA 338 322 324 26.93 25.06 26.97 30.91 29.98 29.7 26.32 30.19666667 450 425 414 328 429.6666667 0.005515983 0.377015479 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 67291 67291 'Ccdc137' mRNA 848.36 842 914.37 15.96 15.45 18.11 10.99 10.97 10.66 16.50666667 10.87333333 660.15 642.94 619.59 868.2433333 640.8933333 2.50E-05 -0.453452217 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0008150///biological_process 67292 67292 'Pigc' mRNA 897 990 1024 14.38 15.76 17.45 14.71 14.44 14.56 15.86333333 14.57 1035 993 991 970.3333333 1006.333333 0.781216872 0.038151649 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0017176///phosphatidylinositol N-acetylglucosaminyltransferase activity GO:0006506///GPI anchor biosynthetic process 67295 67295 'Rab3c' mRNA 112.68 91.28 63.64 1.51 1.34 1.05 0.25 0.01 0.19 1.3 0.15 15.12 2.25 11.07 89.2 9.48 6.63E-12 -3.257084769 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030742///GTP-dependent protein binding+++GO:0031489///myosin V binding GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0019882///antigen processing and presentation+++GO:0072659///protein localization to plasma membrane 67296 67296 'Socs4' mRNA 427 448 354 3.28 3.38 2.88 3.49 3.29 3.64 3.18 3.473333333 524 482 529 409.6666667 511.6666667 0.016354429 0.312340531 04630///JAK-STAT signaling pathway+++04910///Insulin signaling pathway+++04917///Prolactin signaling pathway+++04930///Type II diabetes mellitus GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0008286///insulin receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021819///layer formation in cerebral cortex+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035556///intracellular signal transduction+++GO:0040008///regulation of growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0045444///fat cell differentiation+++GO:0046854///phosphatidylinositol phosphorylation 67298 67298 'Gprasp1' mRNA 3827.24 3758.66 3751.17 35.15 33.95 36.48 15.35 14.37 14.35 35.19333333 14.69 1913.92 1754.01 1738.48 3779.023333 1802.136667 2.21E-60 -1.081743918 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0008333///endosome to lysosome transport+++GO:1990172///G protein-coupled receptor catabolic process 67299 67299 'Dock7' mRNA 942.08 973.96 698.28 6.68 6.93 5.4 5.7 4.75 4.69 6.336666667 5.046666667 907.58 739.08 725.13 871.44 790.5966667 0.288673962 -0.147567223 GO:0008180///COP9 signalosome+++GO:0030424///axon+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0000226///microtubule cytoskeleton organization+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007264///small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0022027///interkinetic nuclear migration+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0043473///pigmentation+++GO:0045200///establishment of neuroblast polarity+++GO:0050767///regulation of neurogenesis+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration 67300 67300 'Cltc' mRNA 6363 6516 6149 51.61 51.96 52.9 65.59 57.47 63.09 52.15666667 62.05 9306 7968 8672 6342.666667 8648.666667 1.14E-13 0.434589028 04142///Lysosome+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease+++05100///Bacterial invasion of epithelial cells GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030118///clathrin coat+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0030132///clathrin coat of coated pit+++GO:0030136///clathrin-coated vesicle+++GO:0030315///T-tubule+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031523///Myb complex+++GO:0032991///protein-containing complex+++GO:0042383///sarcolemma+++GO:0042470///melanosome+++GO:0043209///myelin sheath+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0071439///clathrin complex+++GO:0072686///mitotic spindle+++GO:0098684///photoreceptor ribbon synapse+++GO:0098835///presynaptic endocytic zone membrane+++GO:0098850///extrinsic component of synaptic vesicle membrane+++GO:1990498///mitotic spindle microtubule GO:0003725///double-stranded RNA binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0030506///ankyrin binding+++GO:0031072///heat shock protein binding+++GO:0032051///clathrin light chain binding+++GO:0042277///peptide binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0097718///disordered domain specific binding+++GO:1990381///ubiquitin-specific protease binding "GO:0000278///mitotic cell cycle+++GO:0006886///intracellular protein transport+++GO:0006898///receptor-mediated endocytosis+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0016192///vesicle-mediated transport+++GO:0031623///receptor internalization+++GO:0033572///transferrin transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048268///clathrin coat assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0072583///clathrin-dependent endocytosis+++GO:0090307///mitotic spindle assembly+++GO:0150093///amyloid-beta clearance by transcytosis+++GO:1900126///negative regulation of hyaluronan biosynthetic process+++GO:1903077///negative regulation of protein localization to plasma membrane" 67302 67302 'Zc3h13' mRNA 1069 1079 1013 9.18 9.08 9.18 8.27 7.94 8.26 9.146666667 8.156666667 1110 1043 1076 1053.666667 1076.333333 0.863090843 0.019181251 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0036396///RNA N6-methyladenosine methyltransferase complex GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0080009///mRNA methylation+++GO:2000036///regulation of stem cell population maintenance 67305 67305 'Gpx7' mRNA 214 174 193 10.8 8.67 10.34 19.66 22.37 20.15 9.936666667 20.72666667 447 496 443 193.6666667 462 1.37E-16 1.242636648 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum GO:0004096///catalase activity+++GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity GO:0006979///response to oxidative stress+++GO:0098869///cellular oxidant detoxification 67306 67306 'Zc2hc1a' mRNA 830 908 883 13.46 14.49 15.18 10.5 10.59 10.9 14.37666667 10.66333333 745 734 749 873.6666667 742.6666667 0.017754213 -0.246911944 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 67307 67307 'Pbld2' mRNA 930.74 898 341 10.18 9.71 4.08 2.58 5.23 4.43 7.99 4.08 264.75 542 461 723.2466667 422.5833333 0.204909167 -0.75981108 GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding GO:0009058///biosynthetic process+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060392///negative regulation of SMAD protein signal transduction 67308 67308 'Mrpl46' mRNA 418 452 427 25.79 27.58 27.96 28.25 29.59 30.51 27.11 29.45 525 536 548 432.3333333 536.3333333 0.016298641 0.299607832 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0030054///cell junction GO:0003735///structural constituent of ribosome+++GO:0016787///hydrolase activity GO:0008150///biological_process 673094 673094 'Cd99' mRNA 2 1 0 2.9 1.53 0 2.75 2.81 0 1.476666667 1.853333333 2 2 0 1 1.333333333 0.887233713 0.42699911 04514///Cell adhesion molecules+++04670///Leukocyte transendothelial migration GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0001773///myeloid dendritic cell activation+++GO:0034109///homotypic cell-cell adhesion+++GO:0072683///T cell extravasation+++GO:2000391///positive regulation of neutrophil extravasation 67311 67311 'Nanp' mRNA 441 483 443 19.22 20.74 20.48 19.09 20.5 18.71 20.14666667 19.43333333 503 527 477 455.6666667 502.3333333 0.361830858 0.129788247 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005575///cellular_component GO:0016787///hydrolase activity+++GO:0050124///N-acylneuraminate-9-phosphatase activity GO:0005975///carbohydrate metabolic process+++GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0016311///dephosphorylation+++GO:0046380///N-acetylneuraminate biosynthetic process 67313 67313 'Inava' mRNA 782 790 752 11.76 11.77 11.87 4.24 3.72 3.82 11.8 3.926666667 307 271 261 774.6666667 279.6666667 4.50E-38 -1.482330996 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0000187///activation of MAPK activity+++GO:0002221///pattern recognition receptor signaling pathway+++GO:0002376///immune system process+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032494///response to peptidoglycan+++GO:0032495///response to muramyl dipeptide+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0034334///adherens junction maintenance+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0045087///innate immune response+++GO:0060729///intestinal epithelial structure maintenance+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:1903409///reactive oxygen species biosynthetic process 67317 67317 '1700022I11Rik' mRNA 2 5 1 0.03 0.07 0.02 0.01 0 0 0.04 0.003333333 1 0 0 2.666666667 0.333333333 0.25751396 -2.883283258 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67326 67326 '1700037H04Rik' mRNA 777 783 675 35.7 35.58 32.92 40.06 42.51 41.63 34.73333333 41.4 999 1034 1004 745 1012.333333 3.77E-06 0.433392854 GO:0005575///cellular_component GO:0008157///protein phosphatase 1 binding GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 67331 67331 'Atp8b3' mRNA 0 3 4 0 0.04 0.05 0.06 0.03 0.06 0.03 0.05 6 3 5 2.333333333 4.666666667 0.575937352 0.966431731 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0007030///Golgi organization+++GO:0007339///binding of sperm to zona pellucida+++GO:0015914///phospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation 67332 67332 'Snrpd3' mRNA 497 464 350 62.71 58.29 46.88 62.16 62.7 60.94 55.96 61.93333333 562 551 531 437 548 0.019973776 0.320275284 03040///Spliceosome+++05322///Systemic lupus erythematosus GO:0000243///commitment complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005683///U7 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0097526///spliceosomal tri-snRNP complex GO:0003723///RNA binding+++GO:0019899///enzyme binding+++GO:0070034///telomerase RNA binding+++GO:0071208///histone pre-mRNA DCP binding+++GO:0071209///U7 snRNA binding+++GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006479///protein methylation+++GO:0008380///RNA splicing" 67333 67333 'Stk35' mRNA 1106 990 480 9.65 8.51 4.53 4.21 5.49 5.38 7.563333333 5.026666667 538 698 678 858.6666667 638 0.32124156 -0.420988325 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051321///meiotic cell cycle 67337 67337 'Cstf1' mRNA 502.87 442 467 11.89 10.93 11.63 13.86 13.66 12.77 11.48333333 13.43 639 617.87 569 470.6233333 608.6233333 0.003505798 0.358299116 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005848///mRNA cleavage stimulating factor complex GO:0006397///mRNA processing+++GO:0031124///mRNA 3'-end processing 67338 67338 'Rffl' mRNA 1038.36 985.39 938.39 15.11 14.34 14.74 8.73 8.96 8.72 14.73 8.803333333 688.38 686.15 664.12 987.38 679.55 4.09E-09 -0.549886508 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0055038///recycling endosome membrane GO:0002020///protease binding+++GO:0002039///p53 binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006886///intracellular protein transport+++GO:0006915///apoptotic process+++GO:0010762///regulation of fibroblast migration+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2001271///negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 67341 67341 'Ascl4' mRNA 24 16 37 0.6 0.39 0.98 0.81 0.71 0.47 0.656666667 0.663333333 37 32 21 25.66666667 30 0.778633045 0.195840333 GO:0090575///RNA polymerase II transcription factor complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046983///protein dimerization activity" GO:0006357///regulation of transcription by RNA polymerase II 67343 67343 'Tex43' mRNA 0 2 2 0 0.11 0.12 0.19 0 0.05 0.076666667 0.08 4 0 1 1.333333333 1.666666667 0.922484347 0.277849828 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030317///flagellated sperm motility 67344 67344 'Tctex1d1' mRNA 738 780 816 40.63 43.86 47.5 7.11 5.93 7.04 43.99666667 6.693333333 144 115 142 778 133.6666667 1.39E-74 -2.556433465 GO:0005737///cytoplasm+++GO:0005868///cytoplasmic dynein complex GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement 67345 67345 'Herc4' mRNA 582 569 598 8.3 7.74 9.06 8.96 8.54 8.25 8.366666667 8.583333333 729 689 662 583 693.3333333 0.042352127 0.236284324 04120///Ubiquitin mediated proteolysis GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0045879///negative regulation of smoothened signaling pathway 67358 67358 '1700093K21Rik' mRNA 6 2 7 0.11 0.04 0.14 0.22 0.03 0.12 0.096666667 0.123333333 10 2 5 5 5.666666667 0.923114693 0.14250821 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67367 67367 'Paxbp1' mRNA 466 459 463 6.62 6.42 6.98 6.7 5.7 6.83 6.673333333 6.41 543 451 536 462.6666667 510 0.389119635 0.126853387 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0007517///muscle organ development+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0031062///positive regulation of histone methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000288///positive regulation of myoblast proliferation" 673676 673676 'Gm9602' mRNA 3 0.99 2.99 0.31 0.1 0.33 0.09 0 0 0.246666667 0.03 0.99 0 0 2.326666667 0.33 0.36918796 -3.205220859 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67369 67369 'Qpctl' mRNA 618 634 645 16.67 16.84 18.45 16.44 16.75 15.61 17.32 16.26666667 701 697 644 632.3333333 680.6666667 0.480972652 0.093181697 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008235///metalloexopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016603///glutaminyl-peptide cyclotransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" "GO:0006508///proteolysis+++GO:0017186///peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase" 67370 67370 'Zfp606' mRNA 682 690 699 11.08 10.93 11.39 6.37 6.31 6.17 11.13333333 6.283333333 463 445 453 690.3333333 453.6666667 2.28E-08 -0.618715253 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 67371 67371 'Gtf3c6' mRNA 970 1041 1130 20.98 22.19 25.93 24.12 26.94 25.95 23.03333333 25.67 1283 1398 1336 1047 1339 0.001154385 0.340667186 GO:0000127///transcription factor TFIIIC complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0003677///DNA binding GO:0006383///transcription by RNA polymerase III 67374 67374 'Jam2' mRNA 1735 1880 1854 20.09 21.3 22.48 27.13 24.59 26.37 21.29 26.03 2760 2466 2608 1823 2611.333333 1.75E-11 0.504680613 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0036477///somatodendritic compartment+++GO:0044291///cell-cell contact zone+++GO:0070160///tight junction+++GO:0098636///protein complex involved in cell adhesion GO:0005178///integrin binding+++GO:0005515///protein binding GO:0007162///negative regulation of cell adhesion+++GO:0007286///spermatid development+++GO:0007520///myoblast fusion+++GO:0031642///negative regulation of myelination+++GO:0045123///cellular extravasation+++GO:0050901///leukocyte tethering or rolling+++GO:0071593///lymphocyte aggregation+++GO:0097241///hematopoietic stem cell migration to bone marrow+++GO:0098609///cell-cell adhesion+++GO:2000403///positive regulation of lymphocyte migration 67375 67375 'Qprt' mRNA 160 166 185 8.21 8.42 10.08 25.72 27.43 27.11 8.903333333 26.75333333 575 598 586 170.3333333 586.3333333 1.50E-36 1.769699355 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:1902494///catalytic complex "GO:0003824///catalytic activity+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042802///identical protein binding" GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0034213///quinolinate catabolic process+++GO:0046874///quinolinate metabolic process 67378 67378 'Bbs2' mRNA 964 969 997 20.28 20.05 22.16 7.7 8.78 9.08 20.83 8.52 415 471 483 976.6666667 456.3333333 6.09E-24 -1.109874725 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0032420///stereocilium+++GO:0034464///BBSome+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0060170///ciliary membrane GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0007288///sperm axoneme assembly+++GO:0007601///visual perception+++GO:0008104///protein localization+++GO:0010629///negative regulation of gene expression+++GO:0014824///artery smooth muscle contraction+++GO:0015031///protein transport+++GO:0021756///striatum development+++GO:0021766///hippocampus development+++GO:0021987///cerebral cortex development+++GO:0030030///cell projection organization+++GO:0030534///adult behavior+++GO:0033210///leptin-mediated signaling pathway+++GO:0033365///protein localization to organelle+++GO:0038108///negative regulation of appetite by leptin-mediated signaling pathway+++GO:0040015///negative regulation of multicellular organism growth+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042311///vasodilation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0044321///response to leptin+++GO:0045444///fat cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0048854///brain morphogenesis+++GO:0051216///cartilage development+++GO:0060271///cilium assembly+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:1903441///protein localization to ciliary membrane+++GO:1905515///non-motile cilium assembly 67379 67379 'Dedd2' mRNA 593 633 636 14.59 16 17.3 10.51 10.21 10.81 15.96333333 10.51 466 425 459 620.6666667 450 5.36E-05 -0.477536838 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003677///DNA binding GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0030262///apoptotic nuclear changes+++GO:0042981///regulation of apoptotic process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 67381 67381 'Med4' mRNA 689 746 709 31.95 34.15 34.88 36.47 34.62 34.54 33.66 35.21 903 836 827 714.6666667 855.3333333 0.016879716 0.246681321 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0046966///thyroid hormone receptor binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 67382 67382 'Brd3' mRNA 2412 2193 2355 24 21.51 25.03 17.73 16.43 17.98 23.51333333 17.38 2031 1839 2004 2320 1958 0.001597601 -0.258903107 GO:0000785///chromatin+++GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0031493///nucleosomal histone binding+++GO:0070577///lysine-acetylated histone binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 67383 67383 'Carnmt1' mRNA 483 464.93 246 5.7 5.42 3.09 2.64 3.25 4.13 4.736666667 3.34 258 309 391 397.9766667 319.3333333 0.18899841 -0.312638334 00340///Histidine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0030735///carnosine N-methyltransferase activity+++GO:0042803///protein homodimerization activity GO:0032259///methylation+++GO:0035498///carnosine metabolic process 67384 67384 'Bag4' mRNA 784 763 404 8.74 8.37 4.78 3.79 5.76 4.94 7.296666667 4.83 391 581 494 650.3333333 488.6666667 0.290427186 -0.405917179 04668///TNF signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0051087///chaperone binding "GO:0006915///apoptotic process+++GO:0010763///positive regulation of fibroblast migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0050821///protein stabilization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0072659///protein localization to plasma membrane+++GO:0090367///negative regulation of mRNA modification+++GO:0097178///ruffle assembly+++GO:1903215///negative regulation of protein targeting to mitochondrion+++GO:2001145///negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity" 67387 67387 'Unc50' mRNA 2099 2188 2105 112.87 115.65 121.81 103.34 104.94 93.66 116.7766667 100.6466667 2189 2175 1952 2130.666667 2105.333333 0.778051614 -0.02944438 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0003723///RNA binding GO:0007166///cell surface receptor signaling pathway+++GO:0015031///protein transport+++GO:0034394///protein localization to cell surface 67388 67388 'Rab5if' mRNA 1090 1220 249 65.52 72.5 15.88 27.68 43.07 46.59 51.3 39.11333333 528 801 859 853 729.3333333 0.835427968 -0.204399561 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0097250///mitochondrial respiratory chain supercomplex assembly 67389 67389 'C1qtnf12' mRNA 501 484 541 22.88 21.82 26.21 24.03 22.26 21.43 23.63666667 22.57333333 604 546 521 508.6666667 557 0.440030113 0.115380676 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0010906///regulation of glucose metabolic process+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0045721///negative regulation of gluconeogenesis+++GO:0046324///regulation of glucose import+++GO:0046326///positive regulation of glucose import+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0050728///negative regulation of inflammatory response+++GO:0051897///positive regulation of protein kinase B signaling 67390 67390 'Mrm3' mRNA 198 252 206 7.92 10 8.66 9.18 10.48 8.63 8.86 9.43 266 294 237 218.6666667 265.6666667 0.159260421 0.271701586 GO:0005739///mitochondrion GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0070039///rRNA (guanosine-2'-O-)-methyltransferase activity GO:0000451///rRNA 2'-O-methylation+++GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0032259///methylation 67391 67391 'Fundc2' mRNA 774 763 761 12.96 12.58 13.52 15.63 13.59 13.38 13.02 14.2 1074 912 890 766 958.6666667 0.003070153 0.309861689 GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane GO:0003674///molecular_function GO:0000422///autophagy of mitochondrion 67392 67392 '4833420G17Rik' mRNA 1081.62 1107.77 1132.67 23 23.17 25.9 16.95 14.87 16.45 24.02333333 16.09 917.56 780.4 849 1107.353333 848.9866667 4.69E-05 -0.397432665 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67393 67393 'Cxxc5' mRNA 1530 1514 1187 28.99 28.75 24.75 19.83 19.93 20.32 27.49666667 20.02666667 1085 1059 1123 1410.333333 1089 4.84E-05 -0.379977352 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0008327///methyl-CpG binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II 67397 67397 'Erp29' mRNA 2106 2128 2008 103.35 103.12 104.55 197.83 195.21 193.09 103.6733333 195.3766667 4627 4453 4367 2080.666667 4482.333333 5.48E-78 1.095659124 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0009986///cell surface+++GO:0030133///transport vesicle+++GO:0042470///melanosome GO:0042803///protein homodimerization activity+++GO:0051087///chaperone binding GO:0000187///activation of MAPK activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050709///negative regulation of protein secretion+++GO:1902235///regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 67398 67398 'Srpr' mRNA 7254 7740 7867 136.02 142.84 156.48 128.48 133.25 125.82 145.1133333 129.1833333 7883 7985 7475 7620.333333 7781 0.863090843 0.016431074 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005785///signal recognition particle receptor complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005047///signal recognition particle binding+++GO:0005525///GTP binding GO:0006605///protein targeting+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006886///intracellular protein transport+++GO:0045047///protein targeting to ER 67399 67399 'Pdlim7' mRNA 1109 1150 972 44.64 45.22 41.21 66.2 65.23 69.5 43.69 66.97666667 1841 1749 1806 1077 1798.666667 6.15E-22 0.730448816 GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0031941///filamentous actin GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0051371///muscle alpha-actinin binding GO:0001503///ossification+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0030036///actin cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0061061///muscle structure development 67412 67412 'Soga3' mRNA 34.78 31 12 0.48 0.42 0.17 0.18 0.19 0.15 0.356666667 0.173333333 15 16 12 25.92666667 14.33333333 0.203388995 -0.835449358 GO:0005575///cellular_component+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0010506///regulation of autophagy 67414 67414 'Mfn1' mRNA 738.65 748.34 486.49 8.75 8.71 6.11 5.47 5.3 5.14 7.856666667 5.303333333 531.34 503.25 483.75 657.8266667 506.1133333 0.008344942 -0.382098629 04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031306///intrinsic component of mitochondrial outer membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0098799///outer mitochondrial membrane protein complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0007275///multicellular organism development+++GO:0008053///mitochondrial fusion+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0046039///GTP metabolic process+++GO:0048312///intracellular distribution of mitochondria+++GO:0051646///mitochondrion localization+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0070584///mitochondrion morphogenesis+++GO:0090258///negative regulation of mitochondrial fission+++GO:1990613///mitochondrial membrane fusion 67416 67416 'Armcx2' mRNA 1600 1627 1280 23.69 23.63 20.29 16.25 17.45 16.44 22.53666667 16.71333333 1253 1314 1219 1502.333333 1262 0.005529538 -0.258290217 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67417 67417 'Ears2' mRNA 252.88 286.23 263.81 2.84 2.84 2.96 2.51 2.01 2.64 2.88 2.386666667 278.52 226.68 254.22 267.64 253.14 0.659075281 -0.092630903 00860///Porphyrin metabolism+++00970///Aminoacyl-tRNA biosynthesis+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004818///glutamate-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016874///ligase activity+++GO:0050561///glutamate-tRNA(Gln) ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006424///glutamyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0070127///tRNA aminoacylation for mitochondrial protein translation 67418 67418 'Ppil4' mRNA 1298 1346 1242 24.68 25.19 25.14 22.11 22.6 21.47 25.00333333 22.06 1338 1332 1258 1295.333333 1309.333333 0.970880597 0.004494756 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:1901407///regulation of phosphorylation of RNA polymerase II C-terminal domain 67419 67419 'Armh4' mRNA 277 321 294 4.73 5.45 5.37 6.2 6.33 5.45 5.183333333 5.993333333 405 404 356 297.3333333 388.3333333 0.012276986 0.373490017 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67420 67420 'Far1' mRNA 1813 1877 1767 19.53 19.88 20.21 19.53 17.78 18.12 19.87333333 18.47666667 2087 1855 1877 1819 1939.666667 0.35176218 0.080221327 04146///Peroxisome+++04212///Longevity regulating pathway - worm GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0016491///oxidoreductase activity+++GO:0080019///fatty-acyl-CoA reductase (alcohol-forming) activity+++GO:0102965///alcohol-forming fatty acyl-CoA reductase activity GO:0006629///lipid metabolic process+++GO:0008611///ether lipid biosynthetic process+++GO:0010025///wax biosynthetic process+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0046474///glycerophospholipid biosynthetic process 67422 67422 'Dhdds' mRNA 856 919 882 14.82 15.56 15.95 14.43 14.05 14.17 15.44333333 14.21666667 967 921 910 885.6666667 932.6666667 0.600835269 0.062152861 00900///Terpenoid backbone biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:1904423///dehydrodolichyl diphosphate synthase complex "GO:0002094///polyprenyltransferase activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0045547///dehydrodolichyl diphosphate synthase activity+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006489///dolichyl diphosphate biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0016094///polyprenol biosynthetic process 67425 67425 'Eps8l1' mRNA 268 291 331 3.78 4.03 4.89 3.48 3.27 3.64 4.233333333 3.463333333 281 265 287 296.6666667 277.6666667 0.588154268 -0.111732762 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex GO:0003779///actin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0042608///T cell receptor binding+++GO:0051015///actin filament binding GO:0007266///Rho protein signal transduction+++GO:0016601///Rac protein signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:1900029///positive regulation of ruffle assembly 67426 67426 'Coq8a' mRNA 942.36 1072.78 1051.41 19.2 21.95 23.07 5.79 6.98 5.82 21.40666667 6.196666667 314.12 366.13 317.82 1022.183333 332.69 4.82E-44 -1.632383767 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0043531///ADP binding GO:0006468///protein phosphorylation+++GO:0006744///ubiquinone biosynthetic process+++GO:0016310///phosphorylation 67427 67427 'Rps20' mRNA 1403 1413 1450 22.16 21.96 24.3 31.67 31.69 33.1 22.80666667 32.15333333 2307 2255 2335 1422 2299 1.13E-19 0.679964227 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0097371///MDM2/MDM4 family protein binding+++GO:1990948///ubiquitin ligase inhibitor activity GO:0006412///translation+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1904667///negative regulation of ubiquitin protein ligase activity 67429 67429 'Nudcd1' mRNA 294.44 362.46 302.24 4.65 5.63 5.07 5.18 5.46 5.1 5.116666667 5.246666667 377.42 388.64 360 319.7133333 375.3533333 0.159845215 0.222004955 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 67430 67430 '4921536K21Rik' mRNA 4.08 10 5 0.09 0.21 0.11 0.13 0.09 0.06 0.136666667 0.093333333 7.14 5 3.12 6.36 5.086666667 0.808836173 -0.348157064 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67432 67432 'Hoga1' mRNA 14 20 7 0.47 0.58 0.23 0.49 0.19 0.49 0.426666667 0.39 19 9 19 13.66666667 15.66666667 0.842178703 0.196632036 00330///Arginine and proline metabolism+++00630///Glyoxylate and dicarboxylate metabolism GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008700///4-hydroxy-2-oxoglutarate aldolase activity+++GO:0016829///lyase activity+++GO:0042803///protein homodimerization activity GO:0009436///glyoxylate catabolic process+++GO:0019470///4-hydroxyproline catabolic process+++GO:0033609///oxalate metabolic process+++GO:0042866///pyruvate biosynthetic process+++GO:0046487///glyoxylate metabolic process 67433 67433 'Ccdc127' mRNA 1209.52 1260.35 1341.1 17.58 18.25 20.73 16.39 16.33 15.96 18.85333333 16.22666667 1286.25 1240.46 1194.61 1270.323333 1240.44 0.691557872 -0.049196369 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67434 67434 'Ankrd33b' mRNA 122 112 114 1.97 1.48 2.11 2.97 3.07 3 1.853333333 3.013333333 196.16 190 189 116 191.72 4.15E-04 0.712403468 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 67437 67437 'Ssr3' mRNA 6165 6164 6398 117.71 115.83 129.58 144.53 141.63 144.36 121.04 143.5066667 8709 8335 8423 6242.333333 8489 2.11E-12 0.429531245 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006614///SRP-dependent cotranslational protein targeting to membrane 67439 67439 'Xab2' mRNA 1900 1830 1738 39.71 37.56 38.5 28.29 28.63 26.58 38.59 27.83333333 1545 1524 1405 1822.666667 1491.333333 1.05E-04 -0.300666595 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex GO:0000155///phosphorelay sensor kinase activity+++GO:0003674///molecular_function "GO:0000160///phosphorelay signal transduction system+++GO:0000349///generation of catalytic spliceosome for first transesterification step+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001824///blastocyst development+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006351///transcription, DNA-templated+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0021987///cerebral cortex development" 67440 67440 'Mtpap' mRNA 587 608 612 7.61 7.81 8.41 6.17 5.8 6.47 7.943333333 6.146666667 556 504 554 602.3333333 538 0.160538642 -0.176377084 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0002134///UTP binding+++GO:0003723///RNA binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:1990817///RNA adenylyltransferase activity GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0071044///histone mRNA catabolic process 67441 67441 'Isoc2b' mRNA 85 92 103 5.03 5.38 6.46 4.43 5.87 5.34 5.623333333 5.213333333 86 111 100 93.33333333 99 0.854599791 0.071826712 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0031648///protein destabilization 67442 67442 'Retsat' mRNA 765 830 725 22.23 23.77 22.35 18.78 18.85 18.28 22.78333333 18.63666667 743 728 700 773.3333333 723.6666667 0.358242818 -0.106060978 00830///Retinol metabolism GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane "GO:0016491///oxidoreductase activity+++GO:0051786///all-trans-retinol 13,14-reductase activity" GO:0042572///retinol metabolic process 67443 67443 'Map1lc3b' mRNA 8847 9534 9232 201.05 213.32 222.57 206.32 220.38 201.09 212.3133333 209.2633333 10443 10893 9855 9204.333333 10397 0.016155387 0.163545196 04137///Mitophagy - animal+++04140///Autophagy - animal+++04216///Ferroptosis+++04371///Apelin signaling pathway+++04621///NOD-like receptor signaling pathway+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0005930///axoneme+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044754///autolysosome GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0019904///protein domain specific binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0097001///ceramide binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0000423///mitophagy+++GO:0006914///autophagy+++GO:0006995///cellular response to nitrogen starvation+++GO:0009267///cellular response to starvation+++GO:0016236///macroautophagy+++GO:0032092///positive regulation of protein binding+++GO:0070257///positive regulation of mucus secretion+++GO:0097352///autophagosome maturation 67444 67444 'Ilkap' mRNA 1173 1232 1031.79 49.13 50.18 45.33 37.95 41.97 43.12 48.21333333 41.01333333 1062.47 1130.63 1149.83 1145.596667 1114.31 0.683019115 -0.048649025 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0033262///regulation of nuclear cell cycle DNA replication 67445 67445 'C1qtnf4' mRNA 463.6 462.92 375.54 18.72 18.4 16.51 8.58 9.38 9.38 17.87666667 9.113333333 237.08 241 251.02 434.02 243.0333333 2.10E-09 -0.842223145 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005125///cytokine activity GO:0007165///signal transduction+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0070105///positive regulation of interleukin-6-mediated signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 67446 67446 'Dusp28' mRNA 637 715 745 25.27 27.98 31.35 17.99 17.77 20.38 28.2 18.71333333 521 502 571 699 531.3333333 0.001008402 -0.410105185 GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 67448 67448 'Plxdc2' mRNA 2692.04 2747.94 2680.58 17.41 17.76 18.87 10.48 9.04 9.09 18.01333333 9.536666667 1745.91 1462.73 1505.59 2706.853333 1571.41 5.63E-26 -0.798761872 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix 67451 67451 'Pkp2' mRNA 746 757 443 14.21 14.19 8.95 6.71 9.75 9.17 12.45 8.543333333 405 575 536 648.6666667 505.3333333 0.05736193 -0.357405294 05412///Arrhythmogenic right ventricular cardiomyopathy GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0014704///intercalated disc+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0019215///intermediate filament binding+++GO:0045294///alpha-catenin binding+++GO:0045296///cadherin binding+++GO:0060090///molecular adaptor activity GO:0002159///desmosome assembly+++GO:0002934///desmosome organization+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0016264///gap junction assembly+++GO:0030336///negative regulation of cell migration+++GO:0034334///adherens junction maintenance+++GO:0045110///intermediate filament bundle assembly+++GO:0048496///maintenance of animal organ identity+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0055088///lipid homeostasis+++GO:0072659///protein localization to plasma membrane+++GO:0086001///cardiac muscle cell action potential+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086019///cell-cell signaling involved in cardiac conduction+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098609///cell-cell adhesion+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:2000810///regulation of bicellular tight junction assembly 67452 67452 'Pnpla8' mRNA 1866 2187 1914 22.08 25.2 23.91 19.8 19.12 19.29 23.73 19.40333333 1918 1808 1807 1989 1844.333333 0.165850966 -0.120133403 GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0047499///calcium-independent phospholipase A2 activity+++GO:0102545///phosphatidyl phospholipase B activity GO:0001516///prostaglandin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0008219///cell death+++GO:0016042///lipid catabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0032048///cardiolipin metabolic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0046338///phosphatidylethanolamine catabolic process+++GO:0050482///arachidonic acid secretion+++GO:0055088///lipid homeostasis+++GO:0070328///triglyceride homeostasis+++GO:1900407///regulation of cellular response to oxidative stress 67453 67453 'Slc25a46' mRNA 1500 1519 1473 18.52 18.23 19.06 14.31 13.3 15.57 18.60333333 14.39333333 1346 1221 1423 1497.333333 1330 0.041773633 -0.183367723 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0000266///mitochondrial fission+++GO:0000422///autophagy of mitochondrion+++GO:0006839///mitochondrial transport+++GO:0007005///mitochondrion organization+++GO:0007416///synapse assembly+++GO:0016358///dendrite development+++GO:0021554///optic nerve development+++GO:0021675///nerve development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0022011///myelination in peripheral nervous system+++GO:0031987///locomotion involved in locomotory behavior+++GO:0048936///peripheral nervous system neuron axonogenesis+++GO:0061564///axon development+++GO:0090149///mitochondrial membrane fission 67454 67454 'Ikbip' mRNA 632.53 630.23 660.86 18.82 17.96 20.82 22.45 21.49 23.59 19.2 22.51 989.4 878.61 990.79 641.2066667 952.9333333 5.75E-08 0.557783822 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 67455 67455 'Klhl13' mRNA 584 693 588 9.82 11.36 10.48 15.31 15.87 15.46 10.55333333 15.54666667 1056 1063 1032 621.6666667 1050.333333 2.37E-14 0.746609872 04120///Ubiquitin mediated proteolysis GO:0030496///midbody+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0047485///protein N-terminus binding+++GO:0097602///cullin family protein binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0032465///regulation of cytokinesis+++GO:0051301///cell division 67456 67456 'Ergic2' mRNA 1158.01 1178.37 1219.86 22.49 22.71 24.8 26.77 28.77 27.22 23.33333333 27.58666667 1588.34 1634.75 1521.25 1185.413333 1581.446667 3.57E-06 0.402806232 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0016192///vesicle-mediated transport" 67457 67457 'Frmd8' mRNA 1372 1380 1357 24.36 24.32 25.56 34.75 31.91 31.83 24.74666667 32.83 2228 2013 1974 1369.666667 2071.666667 1.31E-14 0.583892024 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0032760///positive regulation of tumor necrosis factor production+++GO:0090090///negative regulation of canonical Wnt signaling pathway 67458 67458 'Ergic1' mRNA 731 676 573 14.49 13.2 12.12 19.87 19.41 19.35 13.27 19.54333333 1151 1094 1081 660 1108.666667 1.72E-14 0.739465658 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0016192///vesicle-mediated transport" 67459 67459 'Nvl' mRNA 850.58 809.36 713.5 4.75 4.44 4.22 4.28 3.99 4.02 4.47 4.096666667 883.58 805.61 803.45 791.1466667 830.88 0.631744214 0.060498786 03008///Ribosome biogenesis in eukaryotes GO:0000176///nuclear exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:1990275///preribosome binding GO:0006364///rRNA processing+++GO:0032092///positive regulation of protein binding+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0051973///positive regulation of telomerase activity+++GO:1904749///regulation of protein localization to nucleolus 67460 67460 'Decr1' mRNA 838 910 796 16.34 17.46 16.47 18.56 19.26 17.82 16.75666667 18.54666667 1095 1110 1018 848 1074.333333 3.94E-04 0.33121048 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:1902494///catalytic complex "GO:0008670///2,4-dienoyl-CoA reductase (NADPH) activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0070402///NADPH binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0120162///positive regulation of cold-induced thermogenesis 67463 67463 'Poc5' mRNA 469.94 492.51 500.13 7 7.54 8.09 4.98 4.91 5.05 7.543333333 4.98 367.68 355.08 351 487.5266667 357.92 4.11E-04 -0.458683398 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007049///cell cycle+++GO:0008150///biological_process 67464 67464 'Entpd4' mRNA 110.53 0 221.42 1.97 0 4.18 1.71 3.49 1.76 2.05 2.32 110.41 220.05 110.16 110.65 146.8733333 0.881666752 0.360822068 00230///Purine metabolism+++00240///Pyrimidine metabolism+++04142///Lysosome GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0097637///integral component of autophagosome membrane GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005381///iron ion transmembrane transporter activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0036384///cytidine diphosphatase activity+++GO:0043273///CTPase activity+++GO:0045134///uridine-diphosphatase activity GO:0006256///UDP catabolic process+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0046036///CTP metabolic process+++GO:0046712///GDP catabolic process+++GO:0048250///iron import into the mitochondrion+++GO:0055072///iron ion homeostasis 67465 67465 'Sf3a1' mRNA 1785.75 1847.88 1698.81 19.42 19.76 19.6 18.17 18.93 17.47 19.59333333 18.19 1923.84 1957.78 1790.89 1777.48 1890.836667 0.371282796 0.078446666 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:1903241///U2-type prespliceosome assembly" 67466 67466 'Pdcl' mRNA 1069 1162 1155 20.55 21.95 23.58 20.05 19.63 19.34 22.02666667 19.67333333 1208 1150 1129 1128.666667 1162.333333 0.821717602 0.028971153 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection GO:0044877///protein-containing complex binding GO:0006457///protein folding+++GO:0007601///visual perception+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0030030///cell projection organization+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0050896///response to stimulus+++GO:0061084///negative regulation of protein refolding+++GO:1902605///heterotrimeric G-protein complex assembly 67467 67467 'Gpalpp1' mRNA 844.99 814 944.2 8.16 7.71 9.6 7.55 6.54 6.83 8.49 6.973333333 902.53 765.08 798.08 867.73 821.8966667 0.492448657 -0.095232897 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67468 67468 'Mmd' mRNA 486 475 386 12.76 11.94 10.47 33.23 29.14 33.43 11.72333333 31.93333333 1625 1365 1546 449 1512 6.64E-70 1.742119333 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane GO:0004672///protein kinase activity GO:0006468///protein phosphorylation+++GO:0019835///cytolysis+++GO:0032880///regulation of protein localization+++GO:0045666///positive regulation of neuron differentiation+++GO:0045860///positive regulation of protein kinase activity 67469 67469 'Abhd5' mRNA 485 465 461 8.18 7.84 8.36 14.25 13.87 13.66 8.126666667 13.92666667 948 905 886 470.3333333 913 3.63E-21 0.944815586 04923///Regulation of lipolysis in adipocytes GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0004806///triglyceride lipase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0052689///carboxylic ester hydrolase activity" GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0010898///positive regulation of triglyceride catabolic process+++GO:0030154///cell differentiation+++GO:0050996///positive regulation of lipid catabolic process+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0055088///lipid homeostasis 67470 67470 'Abcg8' mRNA 0 0 1 0 0 0.02 0.01 0 0 0.006666667 0.003333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 02010///ABC transporters+++04975///Fat digestion and absorption+++04976///Bile secretion+++04979///Cholesterol metabolism GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0043235///receptor complex "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0120020///intermembrane cholesterol transfer activity" GO:0006869///lipid transport+++GO:0007584///response to nutrient+++GO:0007588///excretion+++GO:0010949///negative regulation of intestinal phytosterol absorption+++GO:0014850///response to muscle activity+++GO:0015914///phospholipid transport+++GO:0015918///sterol transport+++GO:0030299///intestinal cholesterol absorption+++GO:0031667///response to nutrient levels+++GO:0033344///cholesterol efflux+++GO:0038183///bile acid signaling pathway+++GO:0042493///response to drug+++GO:0042632///cholesterol homeostasis+++GO:0045796///negative regulation of intestinal cholesterol absorption+++GO:0055085///transmembrane transport+++GO:0055092///sterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0120009///intermembrane lipid transfer 67471 67471 'Gpatch1' mRNA 357 397 407 6.41 7.01 7.75 6.1 6.02 5.69 7.056666667 5.936666667 391 377 353 387 373.6666667 0.733866094 -0.064718339 GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006397///mRNA processing+++GO:0008150///biological_process 67472 67472 'Mtfr1' mRNA 1807 1866 1866 41.72 41.91 48.58 38.74 38.81 37.65 44.07 38.4 1648 1689 1607 1846.333333 1648 0.033817564 -0.176523485 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000266///mitochondrial fission+++GO:0007005///mitochondrion organization+++GO:0009060///aerobic respiration 67473 67473 'Slc47a1' mRNA 8 11 22 0.2 0.27 0.53 0.09 0.18 0.09 0.333333333 0.12 5 9 5 13.66666667 6.333333333 0.216194482 -1.137769168 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031982///vesicle GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042887///amide transmembrane transporter activity+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0061459///L-arginine transmembrane transporter activity GO:0006812///cation transport+++GO:0015695///organic cation transport+++GO:0042886///amide transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0089718///amino acid import across plasma membrane+++GO:0097638///L-arginine import across plasma membrane+++GO:0098655///cation transmembrane transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:1990961///drug transmembrane export 67474 67474 'Snap29' mRNA 287 310 215 4.55 4.84 3.62 7.93 7.07 7.43 4.336666667 7.476666667 575 501 522 270.6666667 532.6666667 3.91E-12 0.969734513 04130///SNARE interactions in vesicular transport+++04140///Autophagy - animal GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0020018///ciliary pocket membrane+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0098793///presynapse GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016082///synaptic vesicle priming+++GO:0016240///autophagosome membrane docking+++GO:0030030///cell projection organization+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0060271///cilium assembly+++GO:0097352///autophagosome maturation+++GO:0098693///regulation of synaptic vesicle cycle 67475 67475 'Ero1b' mRNA 1440 1517 1342.42 23.06 23.1 22.57 8.33 8.52 8.33 22.91 8.393333333 626 596 572 1433.14 598 1.34E-49 -1.271395194 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane "GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0016972///thiol oxidase activity+++GO:0071949///FAD binding" GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0022417///protein maturation by protein folding+++GO:0030070///insulin processing+++GO:0030198///extracellular matrix organization+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0042593///glucose homeostasis+++GO:0045454///cell redox homeostasis 67477 67477 'Abhd15' mRNA 173 167 160 2.91 2.76 2.85 5.9 5.64 5.48 2.84 5.673333333 404 377 363 166.6666667 381.3333333 4.83E-15 1.18237352 GO:0005576///extracellular region GO:0016787///hydrolase activity+++GO:0034338///short-chain carboxylesterase activity+++GO:0047372///acylglycerol lipase activity GO:0044255///cellular lipid metabolic process 67480 67480 'Cwc25' mRNA 538.79 525.5 547.38 8.89 8.53 9.58 8.38 8.57 7.38 9 8.11 584.61 584.01 498.23 537.2233333 555.6166667 0.839212838 0.035988549 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005684///U2-type spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071006///U2-type catalytic step 1 spliceosome GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 67483 67483 '1700028P14Rik' mRNA 344 262 299 26.32 19.85 24.28 3.01 1.99 1.94 23.48333333 2.313333333 45 29 28 301.6666667 34 2.68E-39 -3.165043615 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67484 67484 'Eepd1' mRNA 301.11 313.25 270.45 2.97 2.91 3.13 7.35 6.43 6.77 3.003333333 6.85 565.65 487.31 508.35 294.9366667 520.4366667 2.16E-10 0.808547993 GO:0046658///anchored component of plasma membrane GO:0003677///DNA binding GO:0006281///DNA repair+++GO:0010875///positive regulation of cholesterol efflux 674842 674842 'Gm9631' mRNA 2 0 1 0.41 0 0.22 0 0.38 0.19 0.21 0.19 0 2 1 1 1 0.999473059 -0.002338935 GO:0005575///cellular_component 67486 67486 'Polr3g' mRNA 134 171 131 2.4 3.02 2.49 1.54 1.61 1.87 2.636666667 1.673333333 99 101 116 145.3333333 105.3333333 0.051347867 -0.472393978 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003682///chromatin binding GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III+++GO:0008283///cell proliferation+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus 67487 67487 'Dhx40' mRNA 787 771 820 11.45 11.04 12.66 8.22 7.7 7.68 11.71666667 7.866666667 650 571 588 792.6666667 603 1.94E-04 -0.409307118 GO:0005622///intracellular GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 67488 67488 'Calcoco1' mRNA 4142 4434 3707 80.91 85.25 76.81 37.46 39.62 38.21 80.99 38.43 2206 2279 2179 4094.333333 2221.333333 4.53E-43 -0.890752285 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070016///armadillo repeat domain binding "GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 67489 67489 'Ap4b1' mRNA 606.32 696.44 542 11.97 13.61 11.61 10.57 9.56 11.23 12.39666667 10.45333333 604.78 540 618.73 614.92 587.8366667 0.617225536 -0.074337922 04142///Lysosome GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030117///membrane coat+++GO:0030124///AP-4 adaptor complex+++GO:0030131///clathrin adaptor complex GO:0005515///protein binding+++GO:0030276///clathrin binding GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0061938///protein localization to somatodendritic compartment 674895 674895 'Nek10' mRNA 359 424 324 2.31 2.55 2.76 0.27 0.35 0.22 2.54 0.28 55 44 37 369 45.33333333 1.89E-48 -3.034149772 GO:0005576///extracellular region+++GO:1902911///protein kinase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1902749///regulation of cell cycle G2/M phase transition 67490 67490 'Ufl1' mRNA 1700 1817 1649 16.71 17.46 17.07 14.16 13.89 12.58 17.08 13.54333333 1686 1609 1450 1722 1581.666667 0.129164494 -0.134055615 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0035861///site of double-strand break+++GO:0043005///neuron projection GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0061666///UFM1 ligase activity+++GO:0071568///UFM1 transferase activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016570///histone modification+++GO:0030218///erythrocyte differentiation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032092///positive regulation of protein binding+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032880///regulation of protein localization+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043066///negative regulation of apoptotic process+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050727///regulation of inflammatory response+++GO:0060218///hematopoietic stem cell differentiation+++GO:0060252///positive regulation of glial cell proliferation+++GO:0061709///reticulophagy+++GO:0071569///protein ufmylation+++GO:1902065///response to L-glutamate+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response+++GO:1990592///protein K69-linked ufmylation 67492 67492 'Zfand4' mRNA 160.55 170.23 134.87 2.27 2.19 2.01 0.68 0.68 0.53 2.156666667 0.63 62.36 59 49.38 155.2166667 56.91333333 3.35E-09 -1.4570257 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 67493 67493 'Mettl16' mRNA 789.56 843.97 809.2 14.29 14.97 15.09 13.61 14.12 12.9 14.78333333 13.54333333 851.67 859 797.88 814.2433333 836.1833333 0.857663786 0.026496203 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0001734///mRNA (N6-adenosine)-methyltransferase activity+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0030629///U6 snRNA 3'-end binding+++GO:0035613///RNA stem-loop binding+++GO:0052907///23S rRNA (adenine(1618)-N(6))-methyltransferase activity+++GO:0120048///U6 snRNA (adenine-(43)-N(6))-methyltransferase activity "GO:0001510///RNA methylation+++GO:0006402///mRNA catabolic process+++GO:0006556///S-adenosylmethionine biosynthetic process+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0032259///methylation+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0061157///mRNA destabilization+++GO:0070475///rRNA base methylation+++GO:0080009///mRNA methylation+++GO:0120049///snRNA (adenine-N6)-methylation+++GO:1905869///negative regulation of 3'-UTR-mediated mRNA stabilization" 67495 67495 'Tmem167b' mRNA 1532 1488 1512 29.48 28.18 30.87 26.86 26.5 27.24 29.51 26.86666667 1606 1547 1577 1510.666667 1576.666667 0.628248432 0.048883915 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0045054///constitutive secretory pathway 67498 67498 'Kcnv1' mRNA 372 421 449.06 3.87 4.53 5.19 0.26 0.23 0.3 4.53 0.263333333 28 26 32 414.02 28.66666667 1.98E-65 -3.867643877 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 67500 67500 'Ccar1' mRNA 1427 1503 1500 17.22 17.78 19.11 22.1 21.53 20.39 18.03666667 21.34 2112 2007 1880 1476.666667 1999.666667 1.34E-07 0.423977553 GO:0005634///nucleus+++GO:0005641///nuclear envelope lumen+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 67501 67501 'Ccdc50' mRNA 1287 1273 1195 9.33 8.98 9.19 10.85 10.46 10.5 9.166666667 10.60333333 1708 1599 1587 1251.666667 1631.333333 1.16E-06 0.370702825 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton GO:0031625///ubiquitin protein ligase binding GO:0007605///sensory perception of sound 67504 67504 'Rnf151' mRNA 3 8 3 0.16 0.41 0.16 0.32 0.18 0.09 0.243333333 0.196666667 7 4 2 4.666666667 4.333333333 0.943804483 -0.111984186 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation 67509 67509 'Saysd1' mRNA 484 450 438 11.52 10.51 11.02 10.04 10.9 9.97 11.01666667 10.30333333 484 509 463 457.3333333 485.3333333 0.635330377 0.07488105 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 67510 67510 'Tvp23b' mRNA 2811 2781 2857 90.74 88.4 97.63 76.22 78.81 75.3 92.25666667 76.77666667 2710 2741 2591 2816.333333 2680.666667 0.310535162 -0.08428448 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0003674///molecular_function GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport 67511 67511 'Tmed9' mRNA 582 604 332 23.77 24.33 14.38 27.09 32.58 43.33 20.82666667 34.33333333 762 894 1179 506 945 0.004005819 0.904725916 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0019905///syntaxin binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0010638///positive regulation of organelle organization+++GO:0015031///protein transport+++GO:0048205///COPI coating of Golgi vesicle 67512 67512 'Agpat2' mRNA 336 348 231 12.87 13.18 9.31 9.82 10.95 13.05 11.78666667 11.27333333 289 314 379 305 327.3333333 0.664494493 0.099154646 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04072///Phospholipase D signaling pathway+++04975///Fat digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0001819///positive regulation of cytokine production+++GO:0006629///lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008544///epidermis development+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0042493///response to drug 67513 67513 'Faap20' mRNA 1171 1138 927 67.27 65.32 57.31 49.98 57.91 54.51 63.3 54.13333333 983 1119 1045 1078.666667 1049 0.736236787 -0.046680646 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0043240///Fanconi anaemia nuclear complex GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0140036///ubiquitin-dependent protein binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019985///translesion synthesis+++GO:0036297///interstrand cross-link repair 67515 67515 'Ttc33' mRNA 964 991 917 32.12 32.6 32.6 21.93 21.08 21.25 32.44 21.42 756 708 701 957.3333333 721.6666667 6.48E-06 -0.419160272 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67516 67516 'Kctd4' mRNA 262 272 262 4.77 4.87 5.06 2.93 2.48 2.5 4.9 2.636666667 185 153 153 265.3333333 163.6666667 4.71E-05 -0.71045765 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0051260///protein homooligomerization 67525 67525 'Trim62' mRNA 1296 1212 609 21.5 19.78 10.71 3.1 4.47 4.07 17.33 3.88 216 303 274 1039 264.3333333 1.91E-08 -1.967527024 GO:0005737///cytoplasm GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0002376///immune system process+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0016567///protein ubiquitination+++GO:0032897///negative regulation of viral transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044314///protein K27-linked ubiquitination+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1902186///regulation of viral release from host cell+++GO:1905036///positive regulation of antifungal innate immune response" 67526 67526 'Atg12' mRNA 1603 1635 1638 35.85 36 38.86 34.03 31.32 32.49 36.90333333 32.61333333 1750 1573 1618 1625.333333 1647 0.961505442 0.005505251 04068///FoxO signaling pathway+++04136///Autophagy - other+++04140///Autophagy - animal+++04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0034045///phagophore assembly site membrane+++GO:0034274///Atg12-Atg5-Atg16 complex GO:0005515///protein binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006501///C-terminal protein lipidation+++GO:0006914///autophagy+++GO:0044804///autophagy of nucleus 67528 67528 'Nudt7' mRNA 591 577 536 23.37 23.64 23.52 20.24 20.25 18.78 23.51 19.75666667 518 492 482 568 497.3333333 0.094791278 -0.202726001 04146///Peroxisome GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix "GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0010945///CoA pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0030145///manganese ion binding+++GO:0030515///snoRNA binding+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity" GO:0009132///nucleoside diphosphate metabolic process+++GO:0015938///coenzyme A catabolic process+++GO:0036114///medium-chain fatty-acyl-CoA catabolic process+++GO:0044580///butyryl-CoA catabolic process+++GO:0046356///acetyl-CoA catabolic process+++GO:0050873///brown fat cell differentiation+++GO:1901289///succinyl-CoA catabolic process+++GO:1902858///propionyl-CoA metabolic process+++GO:1902859///propionyl-CoA catabolic process+++GO:2001294///malonyl-CoA catabolic process 67529 67529 'Fgfr1op2' mRNA 2361 2409 2322 47.28 47.32 49.24 42.26 37.15 38.42 47.94666667 39.27666667 2449 2107 2159 2364 2238.333333 0.273358022 -0.092043934 GO:0005737///cytoplasm GO:0042802///identical protein binding GO:0009611///response to wounding+++GO:0042060///wound healing 67530 67530 'Uqcrb' mRNA 2794 2791 2975 408.83 407.49 462.14 468.87 535.62 492.95 426.1533333 499.1466667 3650 4049 3695 2853.333333 3798 7.57E-07 0.399368846 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0044877///protein-containing complex binding "GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0009060///aerobic respiration" 67532 67532 'Mfap1a' mRNA 2096.93 2364.3 2286.79 33.4 37.05 38.64 28.94 26.25 25.83 36.36333333 27.00666667 2090.87 1852.38 1807.22 2249.34 1916.823333 0.004368242 -0.244770534 GO:0001527///microfibril+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005684///U2-type spliceosomal complex+++GO:0005813///centrosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0071005///U2-type precatalytic spliceosome GO:0005201///extracellular matrix structural constituent "GO:0000398///mRNA splicing, via spliceosome" 67533 67533 'Ppfibp1' mRNA 2336 2330 2194 25.41 24.95 25.28 25.33 24.8 26.33 25.21333333 25.48666667 2687 2555 2698 2286.666667 2646.666667 0.002815203 0.199562625 GO:0048786///presynaptic active zone GO:0007528///neuromuscular junction development+++GO:0050808///synapse organization 67534 67534 'Ttll4' mRNA 494 465 410 3.18 2.93 2.79 2.38 2.16 1.74 2.966666667 2.093333333 427 377 302 456.3333333 368.6666667 0.039856765 -0.318549971 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097731///9+0 non-motile cilium GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070739///protein-glutamic acid ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation+++GO:0018200///peptidyl-glutamic acid modification 675363 675363 'Gm9640' mRNA 9.68 1.74 4.66 0.59 0.11 0.3 0.1 0.32 0.52 0.333333333 0.313333333 1.86 5.78 9.38 5.36 5.673333333 0.955764802 0.095851551 67538 67538 'Zswim3' mRNA 226 257 286 4.65 5.21 6.25 3.2 3.9 3.55 5.37 3.55 179 213 192 256.3333333 194.6666667 0.035959133 -0.411553167 GO:0005575///cellular_component GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 67542 67542 'Cog6' mRNA 1131 1243 1161 21.32 23.06 23.21 19.02 19.51 18.66 22.53 19.06333333 1161 1163 1103 1178.333333 1142.333333 0.612343881 -0.056435976 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0003674///molecular_function GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0070085///glycosylation 67543 67543 'Pabpc6' mRNA 0 4 0 0 0.07 0 0 0.03 0 0.023333333 0.01 0 2 0 1.333333333 0.666666667 0.820872193 -0.947579581 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0031252///cell leading edge+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008022///protein C-terminus binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding "GO:0045070///positive regulation of viral genome replication+++GO:2000623///negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 67544 67544 'Fam120b' mRNA 1543 1698 1658 18.3 19.81 20.86 10.73 11.28 11.2 19.65666667 11.07 1041 1069 1053 1633 1054.333333 4.69E-14 -0.643696042 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005515///protein binding GO:0030154///cell differentiation+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0045444///fat cell differentiation 67547 67547 'Slc39a8' mRNA 1567 1534 1549 25.76 24.67 27.01 11.64 10.34 10.78 25.81333333 10.92 816 716 719 1550 750.3333333 3.45E-34 -1.060358675 04216///Ferroptosis+++05010///Alzheimer disease+++05012///Parkinson disease GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031090///organelle membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0005385///zinc ion transmembrane transporter activity+++GO:0015086///cadmium ion transmembrane transporter activity+++GO:0015087///cobalt ion transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015296///anion:cation symporter activity+++GO:0046873///metal ion transmembrane transporter activity+++GO:0097079///selenite:proton symporter activity "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006487///protein N-linked glycosylation+++GO:0006525///arginine metabolic process+++GO:0006811///ion transport+++GO:0006824///cobalt ion transport+++GO:0006829///zinc ion transport+++GO:0006876///cellular cadmium ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0030001///metal ion transport+++GO:0030026///cellular manganese ion homeostasis+++GO:0030198///extracellular matrix organization+++GO:0042391///regulation of membrane potential+++GO:0055085///transmembrane transport+++GO:0061757///leukocyte adhesion to arterial endothelial cell+++GO:0070574///cadmium ion transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0071578///zinc ion import across plasma membrane+++GO:0097080///plasma membrane selenite transport+++GO:0098711///iron ion import across plasma membrane+++GO:1990079///cartilage homeostasis+++GO:1990540///mitochondrial manganese ion transmembrane transport" 67549 67549 'Gpr89' mRNA 786.12 940 796 19.59 22.55 20.1 19.7 21.45 21.76 20.74666667 20.97 887 925 939 840.7066667 917 0.323776926 0.115803186 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0032580///Golgi cisterna membrane GO:0005244///voltage-gated ion channel activity+++GO:0005515///protein binding+++GO:0008308///voltage-gated anion channel activity GO:0006811///ion transport+++GO:0015031///protein transport+++GO:0015698///inorganic anion transport+++GO:0030217///T cell differentiation+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0043588///skin development+++GO:0051452///intracellular pH reduction 67553 67553 'Gstcd' mRNA 61 68 58 0.95 1.04 0.95 1.27 1.2 1.42 0.98 1.296666667 94 87 102 62.33333333 94.33333333 0.044819927 0.587593239 GO:0005737///cytoplasm GO:0005515///protein binding GO:0008150///biological_process 67554 67554 'Slc25a30' mRNA 94 87 71 3.18 2.9 2.54 3.52 1.91 3.76 2.873333333 3.063333333 119 63 117 84 99.66666667 0.518549226 0.23504202 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015116///sulfate transmembrane transporter activity+++GO:0015117///thiosulfate transmembrane transporter activity+++GO:0015131///oxaloacetate transmembrane transporter activity+++GO:0015140///malate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008272///sulfate transport+++GO:0015709///thiosulfate transport+++GO:0015729///oxaloacetate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0071423///malate transmembrane transport+++GO:1902356///oxaloacetate(2-) transmembrane transport+++GO:1902358///sulfate transmembrane transport 67556 67556 'Pigm' mRNA 489 469 411 3.4 3.21 3.03 3.61 3.42 3.13 3.213333333 3.386666667 597 553 502 456.3333333 550.6666667 0.042754035 0.260937928 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990529///glycosylphosphatidylinositol-mannosyltransferase I complex "GO:0000030///mannosyltransferase activity+++GO:0004376///glycolipid mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0051751///alpha-1,4-mannosyltransferase activity" GO:0006506///GPI anchor biosynthetic process+++GO:0097502///mannosylation 67557 67557 'Larp6' mRNA 252 308 93 6.13 7.37 2.4 2.47 3.81 4.32 5.3 3.533333333 117 176 198 217.6666667 163.6666667 0.555161823 -0.395694142 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0035613///RNA stem-loop binding+++GO:0048027///mRNA 5'-UTR binding+++GO:1990825///sequence-specific mRNA binding GO:0006396///RNA processing+++GO:0006417///regulation of translation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0045727///positive regulation of translation+++GO:1902416///positive regulation of mRNA binding 67561 67561 'Wdr48' mRNA 1579.62 1725.18 1564.1 22.37 24.03 23.5 16.49 16.26 18.04 23.3 16.93 1340.78 1290.66 1419.72 1622.966667 1350.386667 7.61E-04 -0.276797594 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0043130///ubiquitin binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007338///single fertilization+++GO:0008584///male gonad development+++GO:0016579///protein deubiquitination+++GO:0035264///multicellular organism growth+++GO:0043588///skin development+++GO:0048568///embryonic organ development+++GO:0048705///skeletal system morphogenesis+++GO:0048872///homeostasis of number of cells+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072520///seminiferous tubule development+++GO:1902525///regulation of protein monoubiquitination+++GO:1903003///positive regulation of protein deubiquitination+++GO:1905168///positive regulation of double-strand break repair via homologous recombination 67563 67563 'Ciao3' mRNA 884.27 834.95 855.46 20.51 19.43 21.58 20 20.27 18.86 20.50666667 19.71 954.51 941.81 864.02 858.2266667 920.1133333 0.453702353 0.087995191 GO:0097361///CIA complex "GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0001666///response to hypoxia+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0010468///regulation of gene expression+++GO:0016226///iron-sulfur cluster assembly+++GO:0032364///oxygen homeostasis 67564 67564 'Tmem35a' mRNA 151 167 107 4.5 4.91 3.39 8.54 6.54 6.89 4.266666667 7.323333333 329 246 257 141.6666667 277.3333333 1.10E-06 0.96184946 GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0030548///acetylcholine receptor regulator activity GO:0051131///chaperone-mediated protein complex assembly+++GO:2000010///positive regulation of protein localization to cell surface 67568 67568 'Mrfap1' mRNA 13544 13242 12963 485.14 467.66 492.6 505.61 496.76 500.17 481.8 500.8466667 16219 15551 15524 13249.66667 15764.66667 2.19E-06 0.238435545 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0008150///biological_process 67569 67569 'Mgat4c' mRNA 44 64 65 0.53 0.76 0.85 0.03 0.06 0.05 0.713333333 0.046666667 3 5 5 57.66666667 4.333333333 1.17E-10 -3.748577407 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0008454///alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation 67573 67573 'Loxl4' mRNA 10 12 5 0.1 0.12 0.05 0.87 0.8 1.18 0.09 0.95 102 92 134 9 109.3333333 7.99E-18 3.597937994 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0043235///receptor complex "GO:0004720///protein-lysine 6-oxidase activity+++GO:0005044///scavenger receptor activity+++GO:0005507///copper ion binding+++GO:0016491///oxidoreductase activity+++GO:0016641///oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor+++GO:0046872///metal ion binding" GO:0006897///endocytosis+++GO:0018057///peptidyl-lysine oxidation+++GO:0030199///collagen fibril organization 67574 67574 'Alg13' mRNA 98 88 79 3.49 3.09 2.98 3.65 5.33 4.35 3.186666667 4.443333333 118 168 136 88.33333333 140.6666667 0.009706681 0.66480762 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum "GO:0003824///catalytic activity+++GO:0004577///N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0016787///hydrolase activity" GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006508///proteolysis+++GO:0008152///metabolic process+++GO:0048167///regulation of synaptic plasticity+++GO:1901215///negative regulation of neuron death+++GO:1904262///negative regulation of TORC1 signaling 67578 67578 'Patl2' mRNA 0 0 1 0 0 0.03 0.09 0.06 0.15 0.01 0.1 3 2 5 0.333333333 3.333333333 0.160663349 3.205267927 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0002151///G-quadruplex RNA binding+++GO:0003723///RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0030371///translation repressor activity+++GO:0034046///poly(G) binding GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0010607///negative regulation of cytoplasmic mRNA processing body assembly+++GO:0017148///negative regulation of translation+++GO:0033962///cytoplasmic mRNA processing body assembly 67579 67579 'Cpeb4' mRNA 2085 2012 1826 14.51 13.77 13.48 9.72 8 9.57 13.92 9.096666667 1610 1294 1531 1974.333333 1478.333333 4.56E-07 -0.429031319 04114///Oocyte meiosis+++04320///Dorso-ventral axis formation+++04914///Progesterone-mediated oocyte maturation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse+++GO:1990124///messenger ribonucleoprotein complex "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008135///translation factor activity, RNA binding+++GO:0043022///ribosome binding+++GO:0045182///translation regulator activity+++GO:0046872///metal ion binding" GO:0002931///response to ischemia+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0036294///cellular response to decreased oxygen levels+++GO:0042149///cellular response to glucose starvation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0071230///cellular response to amino acid stimulus+++GO:2000766///negative regulation of cytoplasmic translation 67580 67580 'Lrrc18' mRNA 408 403 378 9.49 9.33 9.37 1.17 1.02 1.08 9.396666667 1.09 62 40 37 396.3333333 46.33333333 1.08E-52 -3.110117924 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function 67581 67581 'Tbc1d23' mRNA 3023.93 3122.54 2774.08 22.18 22.78 22.07 17.94 16.34 16.72 22.34333333 17 2614.77 2287.08 2397.58 2973.516667 2433.143333 6.43E-06 -0.300561551 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0071203///WASH complex GO:0005515///protein binding "GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0016192///vesicle-mediated transport+++GO:0031175///neuron projection development+++GO:0032680///regulation of tumor necrosis factor production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0050727///regulation of inflammatory response+++GO:0099041///vesicle tethering to Golgi+++GO:1990403///embryonic brain development" 675812 675812 'Zfp605' mRNA 217.28 231.27 196.33 3.15 3.37 3.09 2.99 3.25 3.14 3.203333333 3.126666667 240.45 251.56 235.87 214.96 242.6266667 0.40226435 0.163796531 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 67582 67582 'Slc25a26' mRNA 180 181 149 5.57 5.49 4.98 4.83 4.22 5.15 5.346666667 4.733333333 176 152.41 188.44 170 172.2833333 0.982178201 0.00766946 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000095///S-adenosyl-L-methionine transmembrane transporter activity GO:0015805///S-adenosyl-L-methionine transport+++GO:0055085///transmembrane transport+++GO:1901962///S-adenosyl-L-methionine transmembrane transport 67586 67586 'Ubxn11' mRNA 2102 2185 2084 58.97 60.23 64.59 8.45 7.83 8.64 61.26333333 8.306666667 328 300 328 2123.666667 318.6666667 5.33E-211 -2.748698312 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0043130///ubiquitin binding GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 67588 67588 'Rnf41' mRNA 1122 1182 1007 13.83 14.29 13.11 12.28 11.9 12.98 13.74333333 12.38666667 1151 1090 1177 1103.666667 1139.333333 0.752944406 0.036276567 04144///Endocytosis GO:0048471///perinuclear region of cytoplasm+++GO:0071782///endoplasmic reticulum tubular network GO:0004842///ubiquitin-protein transferase activity+++GO:0005128///erythropoietin receptor binding+++GO:0005135///interleukin-3 receptor binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030336///negative regulation of cell migration+++GO:0043408///regulation of MAPK cascade+++GO:0045619///regulation of lymphocyte differentiation+++GO:0045637///regulation of myeloid cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0051896///regulation of protein kinase B signaling+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1901525///negative regulation of mitophagy+++GO:2000114///regulation of establishment of cell polarity+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process 67590 67590 'Tctn3' mRNA 527 613 579 10.81 12.36 12.41 7.67 6.85 7.59 11.86 7.37 421 381 403 573 401.6666667 2.40E-05 -0.525578167 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0043065///positive regulation of apoptotic process+++GO:0060271///cilium assembly 67593 67593 '4930519G04Rik' mRNA 2.29 0 0 0.06 0 0 0 0.05 0.03 0.02 0.026666667 0 2.07 1.01 0.763333333 1.026666667 0.868721353 0.611199255 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 675947 675947 'Gm9195' mRNA 972 971 880 11.37 11.17 10.91 1.4 1.01 1.06 11.15 1.156666667 138 97 101 941 112 1.65E-113 -3.082979929 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67596 67596 'Tespa1' mRNA 0 0 3 0 0 0.06 0.11 0.28 0.11 0.02 0.166666667 5 10 6 1 7 0.084695045 2.763875579 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008180///COP9 signalosome+++GO:0016020///membrane+++GO:0036398///TCR signalosome GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0043274///phospholipase binding GO:0008104///protein localization+++GO:0010387///COP9 signalosome assembly+++GO:0033077///T cell differentiation in thymus+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0036399///TCR signalosome assembly+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050862///positive regulation of T cell receptor signaling pathway 67602 67602 'Necap1' mRNA 1197 1283 1273 27.95 29.5 31.53 21.78 22.56 20.89 29.66 21.74333333 1073 1085 996 1251 1051.333333 0.005181051 -0.263745791 GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030125///clathrin vesicle coat+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 67603 67603 'Dusp6' mRNA 1515 1641 1662 29.91 31.89 34.81 58.42 58 58.06 32.20333333 58.16 3404 3301 3276 1606 3327 2.26E-45 1.037091683 04010///MAPK signaling pathway+++05202///Transcriptional misregulation in cancer+++05221///Acute myeloid leukemia GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0010033///response to organic substance+++GO:0010942///positive regulation of cell death+++GO:0014070///response to organic cyclic compound+++GO:0016311///dephosphorylation+++GO:0030154///cell differentiation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0042493///response to drug+++GO:0043065///positive regulation of apoptotic process+++GO:0043409///negative regulation of MAPK cascade+++GO:0051409///response to nitrosative stress+++GO:0060420///regulation of heart growth+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070848///response to growth factor 67604 67604 'Get4' mRNA 2104 2238 1727 56.94 60.13 50.1 35.24 44.99 43.52 55.72333333 41.25 1480 1833 1782 2023 1698.333333 0.015613175 -0.257041808 GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071818///BAT3 complex GO:0051087///chaperone binding GO:0045048///protein insertion into ER membrane+++GO:0051220///cytoplasmic sequestering of protein+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1904378///maintenance of unfolded protein involved in ERAD pathway 67605 67605 'Akt1s1' mRNA 1300 1253 1325 47.02 44.72 51.21 44.14 44.13 42.85 47.65 43.70666667 1325 1276 1272 1292.666667 1291 0.88865062 -0.015588004 04140///Autophagy - animal+++04150///mTOR signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04714///Thermogenesis+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031931///TORC1 complex+++GO:0032991///protein-containing complex GO:0006469///negative regulation of protein kinase activity+++GO:0007219///Notch signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0042981///regulation of apoptotic process+++GO:0043523///regulation of neuron apoptotic process+++GO:0045792///negative regulation of cell size+++GO:0048011///neurotrophin TRK receptor signaling pathway 67606 67606 'Fibin' mRNA 2567 2660 2585 70.38 71.84 75.19 36.34 35.71 36.93 72.47 36.32666667 1524 1462 1499 2604 1495 4.64E-32 -0.813033926 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus GO:0042803///protein homodimerization activity GO:0008150///biological_process+++GO:0010042///response to manganese ion+++GO:0070528///protein kinase C signaling+++GO:0071548///response to dexamethasone 67607 67607 'Zfp788' mRNA 526 540 548 9.31 9.36 10.23 5.74 4.88 5.84 9.633333333 5.486666667 374 309 368 538 350.3333333 1.10E-06 -0.633098968 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 67608 67608 'Narf' mRNA 1618 1705 1787 19.7 20.42 23.08 12.08 11.13 11.26 21.06666667 11.49 1142 1028 1031 1703.333333 1067 1.07E-14 -0.689941384 GO:0005634///nucleus+++GO:0005638///lamin filament+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031981///nuclear lumen GO:0005521///lamin binding GO:0008150///biological_process 67609 67609 '4930453N24Rik' mRNA 590 602 541 18.96 18.53 18.33 17.78 19.7 20.2 18.60666667 19.22666667 592 606 623 577.6666667 607 0.664494493 0.061531681 GO:0005634///nucleus GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process 67610 67610 'Rspry1' mRNA 1397.89 1386.91 1375.5 12.84 13.1 13.88 13.05 12.34 11.86 13.27333333 12.41666667 1395.52 1294.51 1217.31 1386.766667 1302.446667 0.287095801 -0.103210088 GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination+++GO:0051603///proteolysis involved in cellular protein catabolic process 67615 67615 'Ube2r2' mRNA 1178 1296 1155 19.41 21.01 20.19 18.8 21.06 18.63 20.20333333 19.49666667 1313 1437 1260 1209.666667 1336.666667 0.182041853 0.134129368 04120///Ubiquitin mediated proteolysis GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0070848///response to growth factor+++GO:0070936///protein K48-linked ubiquitination+++GO:0090261///positive regulation of inclusion body assembly 67618 67618 'Aasdhppt' mRNA 618 599 560 15.16 14.44 14.66 15.13 14.92 15.59 14.75333333 15.21333333 664 662 643 592.3333333 656.3333333 0.249816237 0.137318452 00770///Pantothenate and CoA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0008897///holo-[acyl-carrier-protein] synthase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0018215///protein phosphopantetheinylation+++GO:0019878///lysine biosynthetic process via aminoadipic acid 67619 67619 'Nob1' mRNA 463 521 498 16.39 18.18 18.7 18.58 19.95 19.45 17.75666667 19.32666667 603 632 611 494 615.3333333 0.01188332 0.305055813 03008///Ribosome biogenesis in eukaryotes "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030688///preribosome, small subunit precursor" GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000469///cleavage involved in rRNA processing+++GO:0007601///visual perception+++GO:0030490///maturation of SSU-rRNA+++GO:0042274///ribosomal small subunit biogenesis 67620 67620 'Lrp2bp' mRNA 8 11 9 0.14 0.17 0.17 0.11 0.08 0.11 0.16 0.1 7 6 7 9.333333333 6.666666667 0.648109849 -0.496620595 GO:0005737///cytoplasm GO:0005515///protein binding GO:0008150///biological_process 67621 67621 'Bend5' mRNA 99 87 86 3.16 2.73 2.91 2.51 1.7 2.06 2.933333333 2.09 91 60 71 90.66666667 74 0.345777395 -0.307351917 GO:0005794///Golgi apparatus GO:0003674///molecular_function+++GO:0003677///DNA binding "GO:0045892///negative regulation of transcription, DNA-templated" 67622 67622 'Mxra7' mRNA 796.51 791.49 395.03 26.2 25.22 13.79 16.08 11.63 17.75 21.73666667 15.15333333 585.31 403.76 613.43 661.01 534.1666667 0.466707099 -0.307262873 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67623 67623 'Tm7sf3' mRNA 2208 2371 1806 36.44 38.54 31.56 21.68 27.6 25.49 35.51333333 24.92333333 1513 1881 1721 2128.333333 1705 0.00167536 -0.324442134 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032024///positive regulation of insulin secretion+++GO:0034620///cellular response to unfolded protein+++GO:0043069///negative regulation of programmed cell death 67628 67628 'Anp32b' mRNA 1595 1693 752 54.73 57.26 27.38 43.44 68.41 65.35 46.45666667 59.06666667 1454 2235 2117 1346.666667 1935.333333 0.235276393 0.53331929 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0042393///histone binding+++GO:0070063///RNA polymerase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001944///vasculature development+++GO:0006334///nucleosome assembly+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0021591///ventricular system development+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0046827///positive regulation of protein export from nucleus+++GO:0048839///inner ear development+++GO:0060021///roof of mouth development+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 67629 67629 'Spc24' mRNA 593.61 538.75 514.18 26.79 24.07 24.74 23.58 27.25 25.56 25.2 25.46333333 608.84 685.01 636.06 548.8466667 643.3033333 0.077192668 0.220192857 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0031262///Ndc80 complex" GO:0003674///molecular_function+++GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0051301///cell division 67630 67630 'Samd8' mRNA 749.66 802.55 690.42 5.68 6.01 5.55 6.51 6.23 6.45 5.746666667 6.396666667 982.73 924.43 947.8 747.5433333 951.6533333 3.37E-04 0.33818224 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0002950///ceramide phosphoethanolamine synthase activity+++GO:0016740///transferase activity+++GO:0033188///sphingomyelin synthase activity+++GO:0047493///ceramide cholinephosphotransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:1905373///ceramide phosphoethanolamine biosynthetic process+++GO:2000303///regulation of ceramide biosynthetic process 67636 67636 'Etfrf1' mRNA 1193.67 1274.17 1107.52 45.34 48.07 44.59 34.36 31.22 35.3 46 33.62666667 1016.86 891.52 989.48 1191.786667 965.9533333 4.50E-04 -0.314234122 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0022904///respiratory electron transport chain 67645 67645 'Armc12' mRNA 0 0 1 0 0 0.06 0.05 0.05 0.15 0.02 0.083333333 1 1 3 0.333333333 1.666666667 0.47209704 2.208753371 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67647 67647 '4930523C07Rik' mRNA 843 849 850 11.37 11.2 12.08 10.9 9.88 10.71 11.55 10.49666667 934 827 889 847.3333333 883.3333333 0.722076041 0.046647993 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67652 67652 'Spaca1' mRNA 4 4 2 0.23 0.22 0.12 0.26 0.1 0.25 0.19 0.203333333 5 2 5 3.333333333 4 0.872094274 0.257456842 GO:0001669///acrosomal vesicle+++GO:0002079///inner acrosomal membrane+++GO:0002080///acrosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0001675///acrosome assembly+++GO:0007283///spermatogenesis 676527 676527 'Gm12248' mRNA 51 46 43 2.57 2.25 2.36 1.06 1.34 1.21 2.393333333 1.203333333 24 31 26 46.66666667 27 0.063963782 -0.797863462 GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000254///C-4 methylsterol oxidase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0008610///lipid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0045654///positive regulation of megakaryocyte differentiation 67654 67654 '4930558C23Rik' mRNA 140 146 123 13.62 14.09 12.7 2.3 1.14 1.5 13.47 1.646666667 27 13 17 136.3333333 19 1.99E-18 -2.855691385 GO:0016020///membrane+++GO:0016021///integral component of membrane 67655 67655 'Ctdp1' mRNA 537 543 193 7.42 7.19 2.49 3.2 6.02 5.11 5.7 4.776666667 287 487 409 424.3333333 394.3333333 0.888377162 -0.090955658 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0051233///spindle midzone GO:0001096///TFIIF-class transcription factor complex binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0030957///Tat protein binding GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0010458///exit from mitosis+++GO:0043923///positive regulation by host of viral transcription+++GO:0051301///cell division+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain 67657 67657 'Rabl3' mRNA 145 157 136 4.1 4.35 4.07 5.29 5.92 5.17 4.173333333 5.46 215 235 204 146 218 0.002943486 0.56900026 GO:0012505///endomembrane system GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0042803///protein homodimerization activity GO:0001779///natural killer cell differentiation+++GO:0006886///intracellular protein transport+++GO:0030183///B cell differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0046578///regulation of Ras protein signal transduction+++GO:0050821///protein stabilization+++GO:1903059///regulation of protein lipidation 67661 67661 'Ift172' mRNA 1827 1934 1811 17.99 18.73 18.92 6.83 6.05 6.4 18.54666667 6.426666667 798 691 725 1857.333333 738 7.68E-61 -1.344119494 GO:0005634///nucleus+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097225///sperm midpiece+++GO:0097228///sperm principal piece+++GO:0097598///sperm cytoplasmic droplet GO:0005515///protein binding+++GO:0008134///transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001841///neural tube formation+++GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0007219///Notch signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008544///epidermis development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009953///dorsal/ventral pattern formation+++GO:0016485///protein processing+++GO:0021522///spinal cord motor neuron differentiation+++GO:0021915///neural tube development+++GO:0031122///cytoplasmic microtubule organization+++GO:0042073///intraciliary transport+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060021///roof of mouth development+++GO:0060173///limb development+++GO:0060271///cilium assembly+++GO:0060348///bone development+++GO:0061525///hindgut development+++GO:0070986///left/right axis specification+++GO:1905515///non-motile cilium assembly 67664 67664 'Rnf125' mRNA 232.02 226.04 261.56 2.43 2.31 2.92 7.68 7.51 7 2.553333333 7.396666667 847.64 810.06 747.72 239.8733333 801.8066667 7.52E-43 1.726294345 04622///RIG-I-like receptor signaling pathway GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0043231///intracellular membrane-bounded organelle GO:0002039///p53 binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032480///negative regulation of type I interferon production+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:1990830///cellular response to leukemia inhibitory factor 67665 67665 'Dctn4' mRNA 2071 1917 2201 29.54 26.89 33.28 26.61 26.18 27.63 29.90333333 26.80666667 2143 2060 2157 2063 2120 0.856966719 0.023801931 04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005869///dynactin complex+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030017///sarcomere GO:0047485///protein N-terminus binding 67666 67666 'Hapln3' mRNA 12 7 9 0.39 0.25 0.36 0.35 0.3 0.26 0.333333333 0.303333333 14 10 8 9.333333333 10.66666667 0.863090843 0.176565868 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0005540///hyaluronic acid binding GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development 67667 67667 'Alkbh8' mRNA 618.91 619.78 561.82 6.9 7.06 6.51 5.87 4.65 4.79 6.823333333 5.103333333 546.64 488.98 480.71 600.17 505.4433333 0.028023524 -0.259296976 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000049///tRNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0005506///iron ion binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016300///tRNA (uracil) methyltransferase activity+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0016740///transferase activity+++GO:0046872///metal ion binding" GO:0002098///tRNA wobble uridine modification+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0030488///tRNA methylation+++GO:0032259///methylation 67669 67669 'Hikeshi' mRNA 549 533 601 34.5 33.52 40.48 39.02 40.12 41.98 36.16666667 40.37333333 711 690 734 561 711.6666667 0.006238319 0.328341029 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016607///nuclear speck GO:0030544///Hsp70 protein binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0030324///lung development+++GO:0034605///cellular response to heat 67671 67671 'Rpl38' mRNA 758 715 1052 284.42 274.09 424.6 292.17 337.77 407.33 327.7033333 345.7566667 872 971 1156 841.6666667 999.6666667 0.471194358 0.227010044 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0033291///eukaryotic 80S initiation complex+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0001501///skeletal system development+++GO:0001503///ossification+++GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0007605///sensory perception of sound+++GO:0022618///ribonucleoprotein complex assembly+++GO:0034463///90S preribosome assembly+++GO:0042474///middle ear morphogenesis+++GO:0048318///axial mesoderm development 67673 67673 'Elob' mRNA 2863 2686 3019 472.81 443.5 529.36 491.49 570.3 557.33 481.89 539.7066667 3385 3811 3693 2856 3629.666667 1.63E-04 0.332107459 04066///HIF-1 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0030891///VCB complex+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0070449///elongin complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016567///protein ubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II 67674 67674 'Trmt112' mRNA 912.31 795.39 910.67 58.27 49.72 62.58 57.02 62.96 57.56 56.85666667 59.18 1021.21 1097.16 975.98 872.79 1031.45 0.048131083 0.227264297 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008276///protein methyltransferase activity+++GO:0016435///rRNA (guanine) methyltransferase activity+++GO:0046982///protein heterodimerization activity GO:0018364///peptidyl-glutamine methylation+++GO:0030488///tRNA methylation+++GO:0031167///rRNA methylation+++GO:0034968///histone lysine methylation+++GO:0070476///rRNA (guanine-N7)-methylation+++GO:2000234///positive regulation of rRNA processing 67675 67675 'Cuta' mRNA 1331 1378 1328 134.02 137.21 142.47 148.97 155.9 142.79 137.9 149.22 1691 1722 1565 1345.666667 1659.333333 4.26E-04 0.290460739 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005507///copper ion binding+++GO:0019899///enzyme binding GO:0008104///protein localization+++GO:0010038///response to metal ion 67676 67676 'Rpp21' mRNA 344 306 317 58.31 51.88 57.05 69.17 81.76 70.52 55.74666667 73.81666667 464 532 455 322.3333333 483.6666667 3.82E-05 0.574448687 GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding+++GO:0046872///metal ion binding "GO:0001682///tRNA 5'-leader removal+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:0042493///response to drug+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 67678 67678 'Lsm3' mRNA 457 515 474 54.08 60.62 59.53 75.04 72.06 71.82 58.07666667 72.97333333 724 676 668 482 689.3333333 5.76E-06 0.504143387 03018///RNA degradation+++03040///Spliceosome GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0120115///Lsm2-8 complex+++GO:1990726///Lsm1-7-Pat1 complex GO:0003723///RNA binding+++GO:0030629///U6 snRNA 3'-end binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0033962///cytoplasmic mRNA processing body assembly" 67680 67680 'Sdhb' mRNA 3326 3359 3204 193.67 193.31 197.97 250.08 247.09 241.32 194.9833333 246.1633333 4926 4745 4595 3296.333333 4755.333333 2.69E-19 0.516820971 00020///Citrate cycle (TCA cycle)+++00190///Oxidative phosphorylation+++01200///Carbon metabolism+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0045273///respiratory chain complex II" "GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0048039///ubiquinone binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051538///3 iron, 4 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006099///tricarboxylic acid cycle+++GO:0006105///succinate metabolic process+++GO:0009060///aerobic respiration+++GO:0022900///electron transport chain+++GO:0022904///respiratory electron transport chain 67681 67681 'Mrpl18' mRNA 1102.35 1052.28 1090.47 72.5 69.33 75.98 90.66 94.06 91.94 72.60333333 92.22 1528.8 1536.79 1493.17 1081.7 1519.586667 1.19E-08 0.477601573 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0008097///5S rRNA binding GO:0006412///translation+++GO:0035928///rRNA import into mitochondrion 67683 67683 'Pbdc1' mRNA 595 625 618 24.93 25.6 27.76 42.5 42.21 40.42 26.09666667 41.71 1217 1183 1076 612.6666667 1158.666667 4.75E-21 0.906482411 GO:0003674///molecular_function GO:0008150///biological_process 67684 67684 'Luc7l3' mRNA 2578 2359 2556 51.28 47.74 54.37 49.72 48.41 49.14 51.13 49.09 2798 2547 2620 2497.666667 2655 0.425852635 0.073583971 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005685///U1 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome GO:0003677///DNA binding+++GO:0003729///mRNA binding GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 67685 67685 'Dnaaf4' mRNA 206 228.92 181.22 5.09 6.28 5.06 1.76 1.77 1.8 5.476666667 1.776666667 87.01 85.59 89.59 205.38 87.39666667 1.54E-09 -1.244854781 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0097730///non-motile cilium GO:0005515///protein binding+++GO:0030331///estrogen receptor binding GO:0001764///neuron migration+++GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0007368///determination of left/right symmetry+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0007611///learning or memory+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0061136///regulation of proteasomal protein catabolic process 67687 67687 '1700011L22Rik' mRNA 1 0 0 0.07 0 0 0.06 0 0 0.023333333 0.02 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67689 67689 'Aldh3b1' mRNA 366.44 410.34 342.64 10.89 11.93 10.8 29.37 28.31 27.28 11.20666667 28.32 1121.19 1052.93 1004.05 373.14 1059.39 2.10E-48 1.496570475 00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0018477///benzaldehyde dehydrogenase (NADP+) activity+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0033721///aldehyde dehydrogenase (NADP+) activity" GO:0006068///ethanol catabolic process+++GO:0006081///cellular aldehyde metabolic process+++GO:0006979///response to oxidative stress+++GO:0034599///cellular response to oxidative stress+++GO:0046185///aldehyde catabolic process 67690 67690 'Prss37' mRNA 1 0 0 0.06 0 0 0.05 0 0 0.02 0.016666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0004252///serine-type endopeptidase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007338///single fertilization+++GO:0007339///binding of sperm to zona pellucida+++GO:0016477///cell migration+++GO:0051604///protein maturation+++GO:0070613///regulation of protein processing+++GO:1905516///positive regulation of fertilization+++GO:2000344///positive regulation of acrosome reaction 67693 67693 'Hypk' mRNA 1056 1062 1117 133.25 133.42 149.61 152.07 171.94 148.27 138.76 157.4266667 1375 1511 1292 1078.333333 1392.666667 3.48E-04 0.356054238 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0047485///protein N-terminus binding GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization 67694 67694 'Ift74' mRNA 1237.03 1234.02 1228 32.82 32.35 34.33 12.44 14.04 13.65 33.16666667 13.37666667 544 580 571 1233.016667 565 6.39E-34 -1.137679627 GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0003682///chromatin binding+++GO:0048487///beta-tubulin binding GO:0003334///keratinocyte development+++GO:0007219///Notch signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0008544///epidermis development+++GO:0030030///cell projection organization+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 67695 67695 'Ost4' mRNA 2759.39 2367.51 3731.95 419.15 359.96 609.24 484.05 508.96 519.12 462.7833333 504.0433333 3695.4 3760.79 3831.41 2952.95 3762.533333 0.26290864 0.326051867 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006486///protein glycosylation+++GO:0018279///protein N-linked glycosylation via asparagine 67698 67698 'Fam174a' mRNA 1436 1524 1419 38.59 40.34 40.45 31.92 35.36 35.73 39.79333333 34.33666667 1366 1477 1480 1459.666667 1441 0.803758307 -0.029064049 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67701 67701 'Wfdc2' mRNA 4687 4666 4228 473.49 469.28 453.58 342.62 330.47 362.53 465.45 345.2066667 3879 3634 3949 4527 3820.666667 1.73E-05 -0.255283249 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 67702 67702 'Rnf149' mRNA 2297 2240 1591 54.37 51.74 40.98 40.58 34.46 39.5 49.03 38.18 1895 1554 1788 2042.666667 1745.666667 0.038707298 -0.232622526 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0035690///cellular response to drug+++GO:0043409///negative regulation of MAPK cascade+++GO:0071466///cellular response to xenobiotic stimulus 67703 67703 'Kirrel3' mRNA 2299.07 2356.28 2129.55 12.59 12.55 12.57 3.85 3.79 3.8 12.57 3.813333333 1241.34 1108.98 1130.91 2261.633333 1160.41 2.75E-42 -0.974768299 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043198///dendritic shaft GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0050839///cell adhesion molecule binding GO:0001764///neuron migration+++GO:0002121///inter-male aggressive behavior+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0021740///principal sensory nucleus of trigeminal nerve development+++GO:0021766///hippocampus development+++GO:0030097///hemopoiesis+++GO:0048812///neuron projection morphogenesis+++GO:0072102///glomerulus morphogenesis+++GO:0098609///cell-cell adhesion 67704 67704 '1810037I17Rik' mRNA 2405 2544 2495 158.5 165.84 174.48 107.22 122.29 117.75 166.2733333 115.7533333 1865 2073 1979 2481.333333 1972.333333 2.01E-05 -0.342786755 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:1901877///negative regulation of calcium ion binding+++GO:1901895///negative regulation of calcium-transporting ATPase activity 67705 67705 '1810058I24Rik' mRNA 888 925 856 110.96 115.06 113.54 155.62 158.63 152.15 113.1866667 155.4666667 1421 1408 1339 889.6666667 1389.333333 1.69E-14 0.631948879 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0045087///innate immune response+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly 67706 67706 'Tmem179b' mRNA 802 778 718 63.25 60.78 60.09 98.21 88.32 98.42 61.37333333 94.98333333 1426 1249 1380 766 1351.666667 1.25E-20 0.807920114 GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0008150///biological_process 67707 67707 'Mrpl24' mRNA 631.83 617.07 655.36 39.91 39.14 45.19 50.43 49.72 50.03 41.41333333 50.06 908.38 870.73 870.51 634.7533333 883.2066667 6.48E-06 0.46288133 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation 67708 67708 'Pcnx4' mRNA 1406.44 1367.98 1236.76 19.33 18.33 17.64 8.57 7.52 8.87 18.43333333 8.32 695.29 598.99 695.02 1337.06 663.1 1.73E-29 -1.022831348 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67709 67709 'Reg4' mRNA 1 2 0 0.07 0.15 0 0.06 0.07 0.06 0.073333333 0.063333333 1 1 1 1 1 0.998591786 0.019955222 05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0008201///heparin binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:2001065///mannan binding GO:0009617///response to bacterium 67710 67710 'Polr2g' mRNA 1259 1388 1358 96.34 105.18 110.27 93.73 102.32 98.36 103.93 98.13666667 1403 1492 1422 1335 1439 0.353463779 0.096025101 03020///RNA polymerase+++05016///Huntington disease "GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex" GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0031369///translation initiation factor binding "GO:0000291///nuclear-transcribed mRNA catabolic process, exonucleolytic+++GO:0006351///transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0045948///positive regulation of translational initiation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening" 67711 67711 'Nsmce1' mRNA 1095 1139 1017 68.23 68.37 68.35 71.5 75.97 75.95 68.31666667 74.47333333 1270 1297 1299 1083.666667 1288.666667 0.004875563 0.239989301 "GO:0000775///chromosome, centromeric region+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0030915///Smc5-Smc6 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097431///mitotic spindle pole" GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0061630///ubiquitin protein ligase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006301///postreplication repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:2001022///positive regulation of response to DNA damage stimulus 67712 67712 'Slc25a37' mRNA 821.57 859.93 722.99 10.26 10.67 9.65 6.42 6.38 6.45 10.19333333 6.416666667 587.87 562.98 571.81 801.4966667 574.22 1.33E-06 -0.491137878 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005381///iron ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015093///ferrous iron transmembrane transporter activity GO:0006811///ion transport+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0048250///iron import into the mitochondrion+++GO:0055072///iron ion homeostasis 67713 67713 'Dnajc19' mRNA 857 960 932 62.76 67.12 68.97 74.33 92.27 76.25 66.28333333 80.95 1050 1214 1003 916.3333333 1089 0.038520874 0.237487333 "GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0098800///inner mitochondrial membrane protein complex+++GO:0099617///matrix side of mitochondrial inner membrane" GO:0001671///ATPase activator activity+++GO:0005515///protein binding GO:0007601///visual perception+++GO:0015031///protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0048806///genitalia development+++GO:0050790///regulation of catalytic activity+++GO:1900208///regulation of cardiolipin metabolic process 677156 677156 'Cyp4f37' mRNA 1.59 2.41 1.51 0.04 0.06 0.04 0.24 0.16 0.24 0.046666667 0.213333333 11.12 7.74 10.69 1.836666667 9.85 0.028024122 2.797827102 GO:0005575///cellular_component "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" 67722 67722 'Actl11' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005869///dynactin complex GO:0003674///molecular_function GO:0008150///biological_process 67724 67724 'Pop1' mRNA 82 92 79 1.35 1.5 1.38 2.23 1.79 1.87 1.41 1.963333333 155 122 126 84.33333333 134.3333333 0.007707648 0.659505943 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex GO:0004526///ribonuclease P activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0016078///tRNA catabolic process+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 67725 67725 'Nudt13' mRNA 567 566 544 8.06 7.91 7.86 7.51 7.14 7.32 7.943333333 7.323333333 609.16 534 558 559 567.0533333 0.960250673 0.007981683 GO:0005739///mitochondrion GO:0000210///NAD+ diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0046872///metal ion binding GO:0006734///NADH metabolic process+++GO:0006742///NADP catabolic process 67726 67726 'Fam114a2' mRNA 1214 1226 1196 26.01 25.88 27.2 23.63 24.69 25.15 26.36333333 24.49 1268 1293 1307 1212 1289.333333 0.436241451 0.0775776 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67727 67727 'Stx17' mRNA 722 748 709 6.57 6.69 6.87 5.99 5.4 5.57 6.71 5.653333333 757 665 683 726.3333333 701.6666667 0.635296773 -0.062405026 04130///SNARE interactions in vesicular transport+++04140///Autophagy - animal GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030868///smooth endoplasmic reticulum membrane+++GO:0030897///HOPS complex+++GO:0031201///SNARE complex+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0044233///Mitochondria-associated ER Membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006906///vesicle fusion+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0016192///vesicle-mediated transport+++GO:0016240///autophagosome membrane docking+++GO:0034497///protein localization to phagophore assembly site+++GO:0048278///vesicle docking+++GO:0061025///membrane fusion+++GO:0097111///endoplasmic reticulum-Golgi intermediate compartment organization+++GO:0097352///autophagosome maturation 67728 67728 'Dph2' mRNA 150 245 215 3.45 5.63 5.35 5.79 6.48 5.64 4.81 5.97 288 320 265 203.3333333 291 0.014444074 0.505007628 GO:0005575///cellular_component GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0090560///2-(3-amino-3-carboxypropyl)histidine synthase activity GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine 67729 67729 'Mansc1' mRNA 527 502 406 12.41 11.64 10.14 8.31 8.31 7.57 11.39666667 8.063333333 406 396 358 478.3333333 386.6666667 0.023351332 -0.314829934 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 677296 677296 'Fcrl6' mRNA 0 2 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0019902///phosphatase binding+++GO:0019903///protein phosphatase binding+++GO:0042289///MHC class II protein binding GO:0007166///cell surface receptor signaling pathway+++GO:0050776///regulation of immune response 67731 67731 'Fbxo32' mRNA 9107.58 8587.67 8703.22 69.36 64.28 70.3 23.67 21.16 23.25 67.98 22.69333333 3579.07 3127.03 3406.13 8799.49 3370.743333 1.98E-113 -1.397906504 04068///FoxO signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030018///Z disc GO:0005515///protein binding GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0014878///response to electrical stimulus involved in regulation of muscle adaptation+++GO:0014889///muscle atrophy+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0016567///protein ubiquitination+++GO:0071549///cellular response to dexamethasone stimulus 67732 67732 'Iah1' mRNA 587 486 518 41.14 33.49 38.59 53.02 59.95 59.75 37.74 57.57333333 865 949 940 530.3333333 918 3.49E-12 0.780439229 GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006629///lipid metabolic process+++GO:0008150///biological_process+++GO:0016042///lipid catabolic process 67733 67733 'Itgb3bp' mRNA 138 140 123 14.65 14.09 14.49 18.64 12.11 14.13 14.41 14.96 202 127 145 133.6666667 158 0.393171081 0.227447599 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007229///integrin-mediated signaling pathway+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051301///cell division" 67736 67736 'Ccdc130' mRNA 575 566 575 14.22 13.08 14.13 9.91 10.3 10.24 13.81 10.15 446 463 449 572 452.6666667 0.003769125 -0.349838652 GO:0005684///U2-type spliceosomal complex+++GO:0071014///post-mRNA release spliceosomal complex GO:0003674///molecular_function GO:0008380///RNA splicing+++GO:0009615///response to virus 67737 67737 'Ttc39d' mRNA 11 8 6 0.31 0.22 0.18 0.05 0.08 0 0.236666667 0.043333333 2 3 0 8.333333333 1.666666667 0.07871116 -2.324773153 GO:0005575///cellular_component GO:0003674///molecular_function GO:0010874///regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0042632///cholesterol homeostasis+++GO:0090181///regulation of cholesterol metabolic process 67738 67738 'Ppid' mRNA 1066 1192 1186 30.64 33.65 35.97 28.63 26.98 29.91 33.42 28.50666667 1147 1052 1154 1148 1117.666667 0.67536551 -0.052486229 04217///Necroptosis+++04218///Cellular senescence+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005528///FK506 binding+++GO:0008134///transcription factor binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding+++GO:0030331///estrogen receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0051879///Hsp90 protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0015031///protein transport+++GO:0034389///lipid droplet organization+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0045070///positive regulation of viral genome replication+++GO:0050714///positive regulation of protein secretion+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0061077///chaperone-mediated protein folding+++GO:0065003///protein-containing complex assembly+++GO:0071492///cellular response to UV-A 67739 67739 'Slc48a1' mRNA 5198 5438 4770 114.55 117.98 111.51 94.91 104.67 94.73 114.68 98.10333333 4954 5335 4787 5135.333333 5025.333333 0.633004077 -0.040372989 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015232///heme transporter activity+++GO:0020037///heme binding GO:0015886///heme transport 67742 67742 'Samsn1' mRNA 16 26 19 0.5 0.8 0.63 8.51 9.88 10.33 0.643333333 9.573333333 314 356 369 20.33333333 346.3333333 2.87E-57 4.081757495 GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042995///cell projection GO:0001784///phosphotyrosine residue binding GO:0002820///negative regulation of adaptive immune response+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0050869///negative regulation of B cell activation 67747 67747 'Ribc2' mRNA 78 81 77 2.41 2.6 2.65 0.29 0.42 0.27 2.553333333 0.326666667 10 14 9 78.66666667 11 8.27E-12 -2.848705842 GO:0003674///molecular_function GO:0008150///biological_process 67749 67749 'Mgarp' mRNA 11 15 15 0.55 0.74 0.79 1.56 0.8 1.12 0.693333333 1.16 36 18 25 13.66666667 26.33333333 0.135667471 0.926497863 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0006626///protein targeting to mitochondrion+++GO:0008089///anterograde axonal transport+++GO:0008090///retrograde axonal transport+++GO:0010822///positive regulation of mitochondrion organization+++GO:0019896///axonal transport of mitochondrion+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0097211///cellular response to gonadotropin-releasing hormone 67752 67752 'Ppp1r32' mRNA 3459 3411 3281 134.63 130.99 135.52 11.22 10.3 11.28 133.7133333 10.93333333 331 296 323 3383.666667 316.6666667 0 -3.429690974 GO:0036064///ciliary basal body GO:0019902///phosphatase binding GO:0008150///biological_process 677525 677525 'LOC677525' mRNA 3.71 1.79 2 0.21 0.1 0.12 0.39 0 0.12 0.143333333 0.17 8.12 0 2.47 2.5 3.53 0.75009672 0.700914209 67753 67753 'Eqtn' mRNA 2 12 7 0.05 0.32 0.24 0.4 0.33 0.09 0.203333333 0.273333333 12 9 4 7 8.333333333 0.863090843 0.238782858 GO:0002079///inner acrosomal membrane+++GO:0002080///acrosomal membrane+++GO:0002081///outer acrosomal membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding GO:0001675///acrosome assembly+++GO:0006897///endocytosis+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0060478///acrosomal vesicle exocytosis 67755 67755 'Ddx47' mRNA 1087 1128 1171 35.61 36.42 40.69 37.45 35.68 38.17 37.57333333 37.1 1314 1222 1296 1128.666667 1277.333333 0.092005457 0.164404684 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors 67759 67759 'Plgrkt' mRNA 317 314 316 23.43 23.35 25.75 43.14 42.27 38.61 24.17666667 41.34 653 611 556 315.6666667 606.6666667 5.29E-14 0.929501059 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0010756///positive regulation of plasminogen activation 67760 67760 'Slc38a2' mRNA 4404 4246 4209 52.51 49.59 52.9 36.95 32.5 35.39 51.66666667 34.94666667 3595 3070 3335 4286.333333 3333.333333 1.86E-08 -0.376216199 04724///Glutamatergic synapse+++04727///GABAergic synapse+++04974///Protein digestion and absorption GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0043025///neuronal cell body GO:0005295///neutral amino acid:sodium symporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport+++GO:0006868///glutamine transport+++GO:0007565///female pregnancy+++GO:0010628///positive regulation of gene expression+++GO:0015804///neutral amino acid transport+++GO:0015825///L-serine transport+++GO:0021987///cerebral cortex development+++GO:0031460///glycine betaine transport+++GO:0032328///alanine transport+++GO:0033120///positive regulation of RNA splicing+++GO:0034198///cellular response to amino acid starvation+++GO:0071260///cellular response to mechanical stimulus+++GO:0080135///regulation of cellular response to stress+++GO:1903841///cellular response to arsenite(3-) 67763 67763 'Prpsap1' mRNA 3249 3460 3274 99.36 104.21 106.12 78.47 76.66 76.93 103.23 77.35333333 2955 2811 2795 3327.666667 2853.666667 3.21E-04 -0.23390377 GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0019900///kinase binding+++GO:0030234///enzyme regulator activity+++GO:0042802///identical protein binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0009165///nucleotide biosynthetic process+++GO:0033673///negative regulation of kinase activity 67767 67767 'Jagn1' mRNA 1002 859 956 51.46 43.54 52.01 49.25 50.97 50.67 49.00333333 50.29666667 1104 1116 1100 939 1106.666667 0.033652506 0.223653698 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002376///immune system process+++GO:0002446///neutrophil mediated immunity+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030223///neutrophil differentiation+++GO:0038158///granulocyte colony-stimulating factor signaling pathway+++GO:0050832///defense response to fungus+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:1904577///cellular response to tunicamycin+++GO:1990266///neutrophil migration 67768 67768 'N6amt1' mRNA 324.81 315.47 335.32 10.53 10.06 11.56 9.77 10.8 10.86 10.71666667 10.47666667 345.26 373.78 370.92 325.2 363.32 0.381510855 0.14705357 GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0035657///eRF1 methyltransferase complex GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0030792///methylarsonite methyltransferase activity+++GO:0036009///protein-glutamine N-methyltransferase activity+++GO:1904047///S-adenosyl-L-methionine binding GO:0006325///chromatin organization+++GO:0009404///toxin metabolic process+++GO:0018364///peptidyl-glutamine methylation+++GO:0018872///arsonoacetate metabolic process+++GO:0030307///positive regulation of cell growth+++GO:0032259///methylation+++GO:0032775///DNA methylation on adenine+++GO:0034968///histone lysine methylation 67769 67769 'Gpatch2' mRNA 858 895 802.8 9.85 10.71 10.08 8.78 8.75 8.93 10.21333333 8.82 823.56 789.7 771 851.9333333 794.7533333 0.302347905 -0.111259244 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016607///nuclear speck GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0010923///negative regulation of phosphatase activity 67770 67770 'Caap1' mRNA 81.01 89 40 2.11 2.35 1.14 1.08 1 1.3 1.866666667 1.126666667 47 42 55 70.00333333 48 0.174697858 -0.542295443 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 67771 67771 'Arpc5' mRNA 2643 2786 2930 79.8 82.88 93.85 193.5 200 189.08 85.51 194.1933333 7367 7433 6967 2786.333333 7255.666667 1.01E-82 1.366472068 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0043005///neuron projection GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0051015///actin filament binding GO:0014909///smooth muscle cell migration+++GO:0016477///cell migration+++GO:0021769///orbitofrontal cortex development+++GO:0030011///maintenance of cell polarity+++GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0051639///actin filament network formation+++GO:0061842///microtubule organizing center localization+++GO:0097581///lamellipodium organization 67772 67772 'Chd8' mRNA 1194 1207 897 7.35 7.3 5.84 5.56 4.98 5.65 6.83 5.396666667 1042 911 1026 1099.333333 993 0.188978811 -0.153654785 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0071339///MLL1 complex GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008013///beta-catenin binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0070016///armadillo repeat domain binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001964///startle response+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007420///brain development+++GO:0007616///long-term memory+++GO:0010468///regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032508///DNA duplex unwinding+++GO:0035176///social behavior+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0048565///digestive tract development+++GO:0060134///prepulse inhibition+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:2000270///negative regulation of fibroblast apoptotic process" 67773 67773 'Kat8' mRNA 589 557.18 616 21.89 20.41 24.27 17.01 14.84 19.25 22.19 17.03333333 526 448 576 587.3933333 516.6666667 0.165833069 -0.200108866 GO:0000123///histone acetyltransferase complex+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016363///nuclear matrix+++GO:0071339///MLL1 complex+++GO:0072487///MSL complex "GO:0003712///transcription coregulator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019899///enzyme binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)+++GO:0046872///metal ion binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific)" "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010506///regulation of autophagy+++GO:0016573///histone acetylation+++GO:0030099///myeloid cell differentiation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 67774 67774 'Borcs5' mRNA 629 655 642 20.64 21.19 22.35 13.65 14.92 13.37 21.39333333 13.98 478 510 453 642 480.3333333 2.40E-04 -0.430419367 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005873///plus-end kinesin complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031224///intrinsic component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098574///cytoplasmic side of lysosomal membrane+++GO:0099078///BORC complex GO:0003674///molecular_function GO:0032418///lysosome localization+++GO:0072384///organelle transport along microtubule+++GO:1903744///positive regulation of anterograde synaptic vesicle transport 67775 67775 'Rtp4' mRNA 2588 2637 2466 131.58 132.42 132.45 171.12 184.31 175.62 132.15 177.0166667 3863 4031 3811 2563.666667 3901.666667 2.07E-21 0.595198157 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0031849///olfactory receptor binding GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006612///protein targeting to membrane+++GO:0051205///protein insertion into membrane+++GO:0051607///defense response to virus 67776 67776 'Vwa5a' mRNA 1209 1196 1182 15.68 15.26 16.26 37.47 34.43 35.79 15.73333333 35.89666667 3323 2981 3074 1195.666667 3126 6.52E-87 1.373572577 GO:0005654///nucleoplasm+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent GO:0008150///biological_process 67778 67778 'Zfp639' mRNA 369 401 410 10.33 11.1 12.53 10.75 9.69 10.05 11.32 10.16333333 434 379 389 393.3333333 400.6666667 0.94871856 0.012048043 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043621///protein self-association+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030307///positive regulation of cell growth+++GO:0043922///negative regulation by host of viral transcription+++GO:0043923///positive regulation by host of viral transcription+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046718///viral entry into host cell" 67781 67781 'Ilf2' mRNA 1789.05 1694.67 1732.12 50.92 47.78 52.36 41.22 43.21 39.07 50.35333333 41.16666667 1659.9 1701.67 1520.91 1738.613333 1627.493333 0.249916596 -0.108258024 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0097020///COPII adaptor activity "GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006897///endocytosis+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated" 67784 67784 'Plxnd1' mRNA 540 570 461 4.13 4.29 3.74 7.24 6.83 7.29 4.053333333 7.12 1090 1005 1064 523.6666667 1053 7.25E-25 0.998707138 GO:0002116///semaphorin receptor complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0017154///semaphorin receptor activity+++GO:0019904///protein domain specific binding GO:0001525///angiogenesis+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001822///kidney development+++GO:0003151///outflow tract morphogenesis+++GO:0003279///cardiac septum development+++GO:0007162///negative regulation of cell adhesion+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007416///synapse assembly+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0032092///positive regulation of protein binding+++GO:0035904///aorta development+++GO:0043087///regulation of GTPase activity+++GO:0043542///endothelial cell migration+++GO:0045765///regulation of angiogenesis+++GO:0050772///positive regulation of axonogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0060976///coronary vasculature development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance 67785 67785 'Zmym4' mRNA 676 597 638 5.16 4.49 5.2 3.37 3.12 3.48 4.95 3.323333333 506 458 508 637 490.6666667 0.001166258 -0.390012185 GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis 67788 67788 'Sfr1' mRNA 2505 2497 2528 92.84 91.25 99.39 92.81 96.03 91.63 94.49333333 93.49 2878 2906 2748 2510 2844 0.024239067 0.167491829 GO:0005634///nucleus+++GO:0032798///Swi5-Sfr1 complex GO:0030374///nuclear receptor transcription coactivator activity "GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0071391///cellular response to estrogen stimulus" 677884 677884 'Pakap' mRNA 1596 1691 1471 12.24 12.67 11.95 14.74 13.52 14.11 12.28666667 14.12333333 2170 1948 2017 1586 2045 9.57E-07 0.355993843 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0051018///protein kinase A binding GO:0007015///actin filament organization+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0008104///protein localization+++GO:0008360///regulation of cell shape 67789 67789 'Dalrd3' mRNA 2980.51 3101.96 2864.44 100.31 102.52 101.5 45.4 45.88 45.12 101.4433333 45.46666667 1555.97 1523.8 1506.4 2982.303333 1528.723333 8.14E-52 -0.975637362 GO:0005575///cellular_component GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004814///arginine-tRNA ligase activity+++GO:0005524///ATP binding GO:0006418///tRNA aminoacylation for protein translation+++GO:0006420///arginyl-tRNA aminoacylation 67790 67790 'Rab39b' mRNA 399 457 437 6.39 7.2 7.42 3.34 3.25 3.23 7.003333333 3.273333333 240 228 225 431 231 1.46E-10 -0.912697312 04140///Autophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0043005///neuron projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031489///myosin V binding GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032482///Rab protein signal transduction+++GO:0050808///synapse organization 67792 67792 'Rgs8' mRNA 5 1 10 0.05 0.01 0.11 0.15 0.28 0.3 0.056666667 0.243333333 19 33 35 5.333333333 29 0.001123121 2.415001395 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0045202///synapse GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0060159///regulation of dopamine receptor signaling pathway 67797 67797 'Snrnp48' mRNA 435 399 422 14.85 16.69 18.28 13.01 12.61 11.99 16.60666667 12.53666667 418 415 383 418.6666667 405.3333333 0.739272063 -0.059691679 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing 67800 67800 'Dgat2' mRNA 189 171 180 4.72 4.21 4.77 4.48 4.41 4.24 4.566666667 4.376666667 206 198 189 180 197.6666667 0.596863322 0.12217302 00561///Glycerolipid metabolism+++04975///Fat digestion and absorption GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:1990578///perinuclear endoplasmic reticulum membrane "GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0004144///diacylglycerol O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0042803///protein homodimerization activity+++GO:0050252///retinol O-fatty-acyltransferase activity" GO:0006071///glycerol metabolic process+++GO:0006629///lipid metabolic process+++GO:0006640///monoacylglycerol biosynthetic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0019432///triglyceride biosynthetic process+++GO:0019915///lipid storage+++GO:0034383///low-density lipoprotein particle clearance+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0035356///cellular triglyceride homeostasis+++GO:0038183///bile acid signaling pathway+++GO:0042572///retinol metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0045722///positive regulation of gluconeogenesis+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0046339///diacylglycerol metabolic process+++GO:0050746///regulation of lipoprotein metabolic process+++GO:0055089///fatty acid homeostasis+++GO:0060613///fat pad development+++GO:0071400///cellular response to oleic acid+++GO:0090181///regulation of cholesterol metabolic process+++GO:0097006///regulation of plasma lipoprotein particle levels 67801 67801 'Pllp' mRNA 4358 4501 4294 132.2 134.54 138.19 62.78 61.26 59.39 134.9766667 61.14333333 2379 2266 2178 4384.333333 2274.333333 2.84E-55 -0.959150384 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043218///compact myelin+++GO:0045121///membrane raft GO:0019911///structural constituent of myelin sheath GO:0006811///ion transport+++GO:0009611///response to wounding+++GO:0042552///myelination 67803 67803 'Limd2' mRNA 897.09 888.25 761.35 16.46 16.06 14.82 30.25 34.11 33.55 15.78 32.63666667 1893.25 2083.71 2038.93 848.8966667 2005.296667 2.34E-48 1.232055629 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 67804 67804 'Snx2' mRNA 1630 1643 1622 44.12 43.67 46.58 100.61 103.02 97.47 44.79 100.3666667 4276 4275 4010 1631.666667 4187 1.70E-93 1.34736165 04144///Endocytosis "GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030904///retromer complex+++GO:0030905///retromer, tubulation complex+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection" GO:0005154///epidermal growth factor receptor binding+++GO:0005158///insulin receptor binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:1990459///transferrin receptor binding+++GO:1990460///leptin receptor binding "GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0034498///early endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0072673///lamellipodium morphogenesis" 67808 67808 'Tprgl' mRNA 1079.93 1058.99 543.2 31.88 30.87 14.83 16.36 16.31 19.79 25.86 17.48666667 803.6 755.77 867.23 894.04 808.8666667 0.723489385 -0.141466533 GO:0005737///cytoplasm+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0044305///calyx of Held+++GO:0045202///synapse+++GO:0048786///presynaptic active zone GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0008150///biological_process+++GO:0051966///regulation of synaptic transmission, glutamatergic" 67809 67809 'Rmdn3' mRNA 828 934 921 20.68 22.97 24.4 18.87 20.06 19.07 22.68333333 19.33333333 869 902 850 894.3333333 873.6666667 0.740213982 -0.046529446 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044232///organelle membrane contact site+++GO:0045171///intercellular bridge+++GO:0097431///mitotic spindle pole GO:0008017///microtubule binding GO:0006874///cellular calcium ion homeostasis+++GO:0006915///apoptotic process+++GO:0030154///cell differentiation 67811 67811 'Poldip2' mRNA 2264 2252 1992 66.25 64.93 61.84 48.82 46.86 49.39 64.34 48.35666667 1918 1797 1878 2169.333333 1864.333333 0.001204343 -0.228705255 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0030496///midbody+++GO:0042645///mitochondrial nucleoid+++GO:0072686///mitotic spindle "GO:0003677///DNA binding+++GO:0030674///protein binding, bridging" GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016242///negative regulation of macroautophagy+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0070584///mitochondrion morphogenesis+++GO:0070987///error-free translesion synthesis+++GO:0090307///mitotic spindle assembly+++GO:1903490///positive regulation of mitotic cytokinesis+++GO:1904531///positive regulation of actin filament binding+++GO:1990874///vascular smooth muscle cell proliferation+++GO:2001108///positive regulation of Rho guanyl-nucleotide exchange factor activity 67812 67812 'Ubxn4' mRNA 2398.8 2444.98 2178.51 31.22 31.27 30.07 32.2 34.53 33.49 30.85333333 33.40666667 2848.65 2986.12 2869.79 2340.763333 2901.52 7.57E-06 0.300516592 04141///Protein processing in endoplasmic reticulum GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003674///molecular_function GO:0006986///response to unfolded protein+++GO:0030433///ubiquitin-dependent ERAD pathway 67815 67815 'Sec14l2' mRNA 73 89 40 1.61 1.93 0.93 1.22 1.04 1.46 1.49 1.24 64 53 74 67.33333333 63.66666667 0.863090843 -0.079968218 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0008047///enzyme activator activity+++GO:0008289///lipid binding+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0050790///regulation of catalytic activity 67819 67819 'Derl1' mRNA 3993 4179 4030 69.52 71.59 74.42 78.15 78.23 77.95 71.84333333 78.11 5165 5050 4989 4067.333333 5068 2.65E-07 0.305070516 04141///Protein processing in endoplasmic reticulum+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0036502///Derlin-1-VIMP complex+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0044322///endoplasmic reticulum quality control compartment GO:0002020///protease binding+++GO:0005047///signal recognition particle binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042288///MHC class I protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0051117///ATPase binding+++GO:0051787///misfolded protein binding+++GO:1990381///ubiquitin-specific protease binding "GO:0006986///response to unfolded protein+++GO:0015031///protein transport+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032092///positive regulation of protein binding+++GO:0034620///cellular response to unfolded protein+++GO:0036503///ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0071712///ER-associated misfolded protein catabolic process" 67821 67821 'Atp1b4' mRNA 1 0 0 0.01 0 0 0 0 0.01 0.003333333 0.003333333 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0098662///inorganic cation transmembrane transport" 67824 67824 'Nmral1' mRNA 164 150 131 6.84 6.12 5.78 14.15 11.73 12.33 6.246666667 12.73666667 392 316 330 148.3333333 346 3.17E-13 1.210900988 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding 67826 67826 'Snap47' mRNA 1881 1922 1920 55.91 56.28 60.57 69.81 69.52 68.47 57.58666667 69.26666667 2696 2624 2566 1907.666667 2628.666667 1.30E-10 0.449663127 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031083///BLOC-1 complex+++GO:0031201///SNARE complex+++GO:0032279///asymmetric synapse+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0016082///synaptic vesicle priming+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0060291///long-term synaptic potentiation+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse 67830 67830 'Rer1' mRNA 2119.5 2154.5 2184.94 76.13 75.81 83.41 95.23 102.41 98.38 78.45 98.67333333 3061.89 3202 3036.75 2152.98 3100.213333 9.03E-13 0.51366507 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0033130///acetylcholine receptor binding "GO:0006621///protein retention in ER lumen+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007528///neuromuscular junction development+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:1903078///positive regulation of protein localization to plasma membrane" 67832 67832 'Brix1' mRNA 636 639 646 13.29 13.14 14.31 15.78 16.47 16.07 13.58 16.10666667 869 886 857 640.3333333 870.6666667 2.02E-05 0.430918332 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003723///RNA binding+++GO:0019843///rRNA binding GO:0000027///ribosomal large subunit assembly+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 67834 67834 'Idh3a' mRNA 2715 2918 2927 63.14 66.82 72.21 54.61 55.99 54.57 67.39 55.05666667 2701 2704 2613 2853.333333 2672.666667 0.193258617 -0.10765892 00020///Citrate cycle (TCA cycle)+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion+++GO:0043209///myelin sheath "GO:0000287///magnesium ion binding+++GO:0004449///isocitrate dehydrogenase (NAD+) activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0046872///metal ion binding+++GO:0051287///NAD binding" GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006734///NADH metabolic process 67836 67836 'Wdr83' mRNA 602.43 696 595 29.71 33.89 31.13 28.5 29.09 30.57 31.57666667 29.38666667 663.48 660.45 687.99 631.1433333 670.64 0.573342067 0.076545164 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome GO:0003674///molecular_function "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001666///response to hypoxia+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0009611///response to wounding+++GO:0032496///response to lipopolysaccharide+++GO:0032635///interleukin-6 production+++GO:0032640///tumor necrosis factor production+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0090594///inflammatory response to wounding" 67838 67838 'Dnajb11' mRNA 2112 2266 2166 59.92 63.21 65.04 73.15 79.87 76.35 62.72333333 76.45666667 2945 3147 2990 2181.333333 3027.333333 1.41E-10 0.461455644 04141///Protein processing in endoplasmic reticulum GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0101031///chaperone complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0051787///misfolded protein binding GO:0006457///protein folding+++GO:0016556///mRNA modification+++GO:0032781///positive regulation of ATPase activity+++GO:0050768///negative regulation of neurogenesis+++GO:0051604///protein maturation 67839 67839 'Gpsm1' mRNA 970.46 1163 756 19.97 24.3 18.28 15.48 13.48 16.08 20.85 15.01333333 802 699 809 963.1533333 770 0.011049783 -0.327666581 05030///Cocaine addiction GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0001965///G-protein alpha-subunit binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016239///positive regulation of macroautophagy+++GO:0030154///cell differentiation+++GO:0034260///negative regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity 67840 67840 'Mrpl57' mRNA 553 547 600 12.98 12.44 14.81 15.4 15.23 15.01 13.41 15.21333333 750 723 708 566.6666667 727 0.002821821 0.344858332 GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 67841 67841 'Atg3' mRNA 1160 1210 654 32.83 33.72 19.61 29.88 43.89 39.04 28.72 37.60333333 1214 1741 1536 1008 1497 0.078724064 0.57598371 04136///Autophagy - other+++04140///Autophagy - animal+++05167///Kaposi sarcoma-associated herpesvirus infection GO:0000153///cytoplasmic ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0019776///Atg8 ligase activity+++GO:0019777///Atg12 transferase activity+++GO:0019787///ubiquitin-like protein transferase activity+++GO:0019899///enzyme binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006464///cellular protein modification process+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0016567///protein ubiquitination+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0044804///autophagy of nucleus+++GO:0050765///negative regulation of phagocytosis+++GO:1902017///regulation of cilium assembly 67842 67842 'Nop9' mRNA 569.04 605.75 407.22 8.04 8.42 6.11 6.94 10.41 10.62 7.523333333 9.323333333 565.25 827.96 837.62 527.3366667 743.61 0.003118913 0.495397278 "GO:0005730///nucleolus+++GO:0030686///90S preribosome+++GO:0030688///preribosome, small subunit precursor" GO:0003723///RNA binding "GO:0000056///ribosomal small subunit export from nucleus+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 67843 67843 'Slc35a4' mRNA 3192 3074 3138.51 62.39 59.08 64.97 65.66 66.8 60.82 62.14666667 64.42666667 3853.87 3820.86 3451.35 3134.836667 3708.693333 0.001697002 0.229343194 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0032056///positive regulation of translation in response to stress+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport 67844 67844 'Rab32' mRNA 114 159 150 3.15 4.33 4.4 40.65 36.89 38.77 3.96 38.77 1691 1498 1561 141 1583.333333 3.89E-183 3.475839104 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030742///GTP-dependent protein binding+++GO:0035650///AP-1 adaptor complex binding+++GO:0035651///AP-3 adaptor complex binding+++GO:0036461///BLOC-2 complex binding GO:0006886///intracellular protein transport+++GO:0007005///mitochondrion organization+++GO:0016192///vesicle-mediated transport+++GO:0019882///antigen processing and presentation+++GO:0032438///melanosome organization+++GO:0035646///endosome to melanosome transport+++GO:0072657///protein localization to membrane+++GO:0090382///phagosome maturation+++GO:1903232///melanosome assembly 67845 67845 'Rnf115' mRNA 675 687 395 16.77 16.79 10.44 14.05 20.4 18.51 14.66666667 17.65333333 651 921 827 585.6666667 799.6666667 0.010870992 0.45240175 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0051865///protein autoubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination 67846 67846 'Tmem39a' mRNA 442 503 500 12.82 13.48 15.28 19.85 17.74 21.2 13.86 19.59666667 803 747 843 481.6666667 797.6666667 3.47E-10 0.714258612 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006914///autophagy+++GO:0045070///positive regulation of viral genome replication+++GO:1901097///negative regulation of autophagosome maturation+++GO:1902902///negative regulation of autophagosome assembly 67847 67847 'Sncaip' mRNA 477 450 385 6.8 6.23 5.64 4.76 4.23 5.21 6.223333333 4.733333333 388 332 400 437.3333333 373.3333333 0.105565475 -0.237825676 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding GO:0008219///cell death+++GO:0042417///dopamine metabolic process+++GO:0046928///regulation of neurotransmitter secretion+++GO:0090083///regulation of inclusion body assembly 67848 67848 'Ddx55' mRNA 353 388 378.97 7.64 8.18 8.64 6.19 5.54 6.16 8.153333333 5.963333333 329 290 306 373.3233333 308.3333333 0.054897796 -0.288141441 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 67849 67849 'Cdca5' mRNA 7 5 2 0.21 0.15 0.06 4.62 4.66 4.72 0.14 4.666666667 177 174 175 4.666666667 175.3333333 3.84E-30 5.223716934 05206///MicroRNAs in cancer GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0000278///mitotic cell cycle+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007076///mitotic chromosome condensation+++GO:0007080///mitotic metaphase plate congression+++GO:0031536///positive regulation of exit from mitosis+++GO:0051301///cell division+++GO:0071922///regulation of cohesin loading 67851 67851 'Mtres1' mRNA 325 368 350 21.08 24.07 24.6 18.08 26.11 21.28 23.25 21.82333333 317 452 359 347.6666667 376 0.622828917 0.103763076 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0043023///ribosomal large subunit binding GO:0072344///rescue of stalled ribosome+++GO:1903108///regulation of mitochondrial transcription 67855 67855 'Asprv1' mRNA 31 36 15 1.19 1.36 0.61 0.8 0.55 1.1 1.053333333 0.816666667 24 16 32 27.33333333 24 0.797744461 -0.186448854 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0043588///skin development 67856 67856 'Echdc3' mRNA 247 235 210 7.85 7.36 7.08 8.77 9.26 8.54 7.43 8.856666667 317 327 299 230.6666667 314.3333333 0.005803646 0.436972422 GO:0005739///mitochondrion GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016836///hydro-lyase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:1900078///positive regulation of cellular response to insulin stimulus 67857 67857 'Ppp6c' mRNA 1427 1445 1477 27.04 27.38 30.19 33.54 35.56 35.65 28.20333333 34.91666667 1888 1872 1847 1449.666667 1869 7.65E-06 0.353470443 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0045087///innate immune response 67859 67859 'Cysrt1' mRNA 6 8 13 0.53 0.7 1.21 0.61 0.32 0.48 0.813333333 0.47 8 4 6 9 6 0.58727806 -0.615364484 GO:0042802///identical protein binding GO:0008150///biological_process 67860 67860 'S100a16' mRNA 2344 2496 2470 142.7 150.32 159.9 167.46 172.83 167.27 150.9733333 169.1866667 3153 3155 3063 2436.666667 3123.666667 9.55E-07 0.345536438 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0051592///response to calcium ion 67861 67861 'Akr1b10' mRNA 508 555 522 22.79 24.58 24.85 29.08 28.28 29.01 24.07333333 28.79 744 706 718 528.3333333 722.6666667 4.09E-05 0.439846227 00040///Pentose and glucuronate interconversions+++00051///Fructose and mannose metabolism+++00052///Galactose metabolism+++00561///Glycerolipid metabolism+++00790///Folate biosynthesis GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0001758///retinal dehydrogenase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0016491///oxidoreductase activity+++GO:0016918///retinal binding+++GO:0045550///geranylgeranyl reductase activity+++GO:0047718///indanol dehydrogenase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0070401///NADP+ binding+++GO:0070402///NADPH binding GO:0001523///retinoid metabolic process+++GO:0016488///farnesol catabolic process+++GO:0042572///retinol metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process+++GO:0110095///cellular detoxification of aldehyde 67862 67862 '2310033P09Rik' mRNA 400 367 352 19.63 17.78 18.33 13.25 15.65 13.4 18.58 14.1 310 357 303 373 323.3333333 0.177953027 -0.215920976 GO:0005575///cellular_component GO:0008150///biological_process 67863 67863 'Slc25a11' mRNA 3349.26 3540.15 3269.31 107.42 110.88 110.81 104.32 104.65 103.09 109.7033333 104.02 3798.67 3721.82 3627.53 3386.24 3716.006667 0.057830692 0.122611042 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015116///sulfate transmembrane transporter activity+++GO:0015117///thiosulfate transmembrane transporter activity+++GO:0015131///oxaloacetate transmembrane transporter activity+++GO:0015139///alpha-ketoglutarate transmembrane transporter activity+++GO:0015140///malate transmembrane transporter activity+++GO:0015141///succinate transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008272///sulfate transport+++GO:0015709///thiosulfate transport+++GO:0015729///oxaloacetate transport+++GO:0015742///alpha-ketoglutarate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0071422///succinate transmembrane transport+++GO:0071423///malate transmembrane transport+++GO:1902356///oxaloacetate(2-) transmembrane transport+++GO:1902358///sulfate transmembrane transport 67864 67864 'Yipf4' mRNA 2438 2657 2472 64.63 69.38 69.52 54.81 51.18 53.47 67.84333333 53.15333333 2377 2167 2245 2522.333333 2263 0.021032791 -0.168832998 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus 67865 67865 'Rgs10' mRNA 87 67 77 6.52 5.02 5.99 48.83 50.66 51.48 5.843333333 50.32333333 757 760 771 77 762.6666667 4.69E-106 3.29644324 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043679///axon terminus GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0001975///response to amphetamine+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0043547///positive regulation of GTPase activity 67866 67866 'Wfdc1' mRNA 177 162 179 9.35 8.45 10.03 20.67 20.34 21.18 9.276666667 20.73 449 431 445 172.6666667 441.6666667 6.06E-20 1.341524706 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0001558///regulation of cell growth+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0032355///response to estradiol+++GO:0042493///response to drug+++GO:0043086///negative regulation of catalytic activity+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0052547///regulation of peptidase activity+++GO:0061045///negative regulation of wound healing 67867 67867 'Lrrc28' mRNA 371 418 365 7.36 8.01 7.55 5.82 6.3 6.08 7.64 6.066666667 331 353 334 384.6666667 339.3333333 0.212116608 -0.190753438 GO:0005575///cellular_component GO:0003674///molecular_function 67869 67869 'Paip2' mRNA 4278 4409 4316 164.55 166.74 176.5 155.91 158.46 150.56 169.2633333 154.9766667 4580 4512 4295 4334.333333 4462.333333 0.73018242 0.029459236 GO:0005737///cytoplasm "GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0003729///mRNA binding+++GO:0008143///poly(A) binding+++GO:0030371///translation repressor activity" GO:0006417///regulation of translation+++GO:0007283///spermatogenesis+++GO:0007613///memory+++GO:0017148///negative regulation of translation+++GO:0045947///negative regulation of translational initiation+++GO:1900271///regulation of long-term synaptic potentiation 67870 67870 'Enoph1' mRNA 744 660 600.22 23.87 20.94 20.26 19.05 19.83 19.54 21.69 19.47333333 682.1 693.07 683.21 668.0733333 686.1266667 0.8580564 0.029144622 00270///Cysteine and methionine metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0043715///2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity+++GO:0043716///2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity+++GO:0043874///acireductone synthase activity+++GO:0046872///metal ion binding" GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0016311///dephosphorylation+++GO:0019284///L-methionine salvage from S-adenosylmethionine+++GO:0019509///L-methionine salvage from methylthioadenosine 67871 67871 'Mrrf' mRNA 351.41 376 319.25 8.55 8.97 8.25 9.71 10.26 9.45 8.59 9.806666667 458.16 472.33 432.2 348.8866667 454.23 0.005393671 0.371545701 GO:0005739///mitochondrion GO:0043023///ribosomal large subunit binding GO:0006412///translation+++GO:0032790///ribosome disassembly 67872 67872 'Nsmce4a' mRNA 361 350 211 14.97 14.32 9.28 12.67 6.96 12.61 12.85666667 10.74666667 351 188 338 307.3333333 292.3333333 0.805365555 -0.077799261 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0030915///Smc5-Smc6 complex" GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:2001022///positive regulation of response to DNA damage stimulus 67873 67873 'Mri1' mRNA 329.74 274.61 306.9 8.67 7.11 8.56 7.81 9.75 7.55 8.113333333 8.37 341.5 416.21 319.67 303.75 359.1266667 0.203388995 0.231588378 00270///Cysteine and methionine metabolism GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0046523///S-methyl-5-thioribose-1-phosphate isomerase activity GO:0008652///cellular amino acid biosynthetic process+++GO:0009086///methionine biosynthetic process+++GO:0019284///L-methionine salvage from S-adenosylmethionine+++GO:0019509///L-methionine salvage from methylthioadenosine+++GO:0044237///cellular metabolic process+++GO:0044249///cellular biosynthetic process 67874 67874 'Rprm' mRNA 820 841 678 33.33 33.72 29.23 38.11 38.41 38.59 32.09333333 38.37 1077 1059 1055 779.6666667 1063.666667 3.06E-06 0.439950933 04115///p53 signaling pathway GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007050///cell cycle arrest+++GO:0007346///regulation of mitotic cell cycle+++GO:0051726///regulation of cell cycle 67876 67876 'Coq10b' mRNA 625 647 675 20.91 21.33 23.93 37.36 34.62 36.25 22.05666667 36.07666667 1284 1162 1201 649 1215.666667 7.00E-21 0.891175687 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0048039///ubiquinone binding GO:0006744///ubiquinone biosynthetic process+++GO:0045333///cellular respiration 67877 67877 'Naa20' mRNA 1546 1616 1602 83.67 86.43 92.04 99.19 105.74 96.94 87.38 100.6233333 2101 2183 1983 1588 2089 1.66E-06 0.383221913 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031416///NatB complex "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0017196///N-terminal peptidyl-methionine acetylation 67878 67878 'Tmem33' mRNA 2165 2272 2148 18.64 19.15 19.52 18.75 17.16 18.44 19.10333333 18.11666667 2527 2259 2405 2195 2397 0.134187598 0.114519117 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0042470///melanosome GO:0005515///protein binding GO:0034976///response to endoplasmic reticulum stress+++GO:0061024///membrane organization+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:1903371///regulation of endoplasmic reticulum tubular network organization+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:1903899///positive regulation of PERK-mediated unfolded protein response 67880 67880 'Dcxr' mRNA 656.67 617.37 557.98 21.9 20.32 19.76 34.63 34.24 34.51 20.66 34.46 1195.05 1153.04 1152 610.6733333 1166.696667 2.00E-24 0.925456919 00040///Pentose and glucuronate interconversions GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0016324///apical plasma membrane "GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016614///oxidoreductase activity, acting on CH-OH group of donors+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0042802///identical protein binding+++GO:0044105///L-xylulose reductase (NAD+) activity+++GO:0050038///L-xylulose reductase (NADP+) activity" GO:0005975///carbohydrate metabolic process+++GO:0005997///xylulose metabolic process+++GO:0006006///glucose metabolic process+++GO:0006739///NADP metabolic process+++GO:0042732///D-xylose metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process 67881 67881 'Mdp1' mRNA 1022 1116 1082 35.71 38.44 40.11 33.66 35.46 33.59 38.08666667 34.23666667 1107 1137.95 1069 1073.333333 1104.65 0.825432212 0.028835982 GO:0003993///acid phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0030389///fructosamine metabolic process+++GO:0035335///peptidyl-tyrosine dephosphorylation 67883 67883 'Uxs1' mRNA 531.87 471.97 394.52 6.11 5.33 4.8 6.77 5.9 6.33 5.413333333 6.333333333 678.82 578.12 614.39 466.12 623.7766667 0.00115842 0.412640884 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane+++GO:1902494///catalytic complex GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0048040///UDP-glucuronate decarboxylase activity+++GO:0070403///NAD+ binding GO:0033320///UDP-D-xylose biosynthetic process+++GO:0042732///D-xylose metabolic process 67884 67884 'Cfap410' mRNA 1933 1960 1864 63.51 63.51 64.93 50.95 45.72 48.96 63.98333333 48.54333333 1765 1536 1628 1919 1643 0.002081939 -0.23661942 GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097733///photoreceptor cell cilium GO:0003674///molecular_function "GO:0006974///cellular response to DNA damage stimulus+++GO:0007010///cytoskeleton organization+++GO:0007224///smoothened signaling pathway+++GO:0008360///regulation of cell shape+++GO:0030030///cell projection organization+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0060271///cilium assembly" 67885 67885 'Mtln' mRNA 462 476 459 38.95 39.78 41.07 34.32 34.79 30.67 39.93333333 33.26 466 460 402 465.6666667 442.6666667 0.593573285 -0.085198966 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0005515///protein binding GO:0006635///fatty acid beta-oxidation+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0031334///positive regulation of protein complex assembly+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0044255///cellular lipid metabolic process+++GO:0045333///cellular respiration+++GO:0051146///striated muscle cell differentiation+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0070328///triglyceride homeostasis 67886 67886 'Camsap2' mRNA 959 971 790 7.59 7.65 6.8 6.15 5.41 5.02 7.346666667 5.526666667 843 735 670 906.6666667 749.3333333 0.011620549 -0.284403009 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0036064///ciliary basal body+++GO:0036449///microtubule minus-end+++GO:0042995///cell projection+++GO:1990752///microtubule end GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008017///microtubule binding+++GO:0030507///spectrin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0031113///regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031175///neuron projection development+++GO:0033043///regulation of organelle organization+++GO:0050773///regulation of dendrite development+++GO:0061564///axon development+++GO:1903358///regulation of Golgi organization 67887 67887 'Saraf' mRNA 8444 8936 8364 257.06 268.06 270.12 189.57 194.12 188.74 265.08 190.81 7158 7155 6897 8581.333333 7070 9.63E-08 -0.290993189 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:2001256///regulation of store-operated calcium entry 67888 67888 'Tmem100' mRNA 15 31 20 0.6 1.12 0.86 3.05 3.53 3.16 0.86 3.246666667 91 101 88 22 93.33333333 7.84E-09 2.077477238 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043204///perikaryon+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0003197///endocardial cushion development+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030509///BMP signaling pathway+++GO:0043491///protein kinase B signaling+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051930///regulation of sensory perception of pain+++GO:0060842///arterial endothelial cell differentiation+++GO:0071773///cellular response to BMP stimulus+++GO:2001214///positive regulation of vasculogenesis 67889 67889 'Rbm18' mRNA 994.59 1006 1061.75 21.73 21.62 24.62 21.73 20.67 22.02 22.65666667 21.47333333 1141.84 1061.67 1120.8 1020.78 1108.103333 0.341169891 0.103794797 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0003676///nucleic acid binding+++GO:0003723///RNA binding 67890 67890 'Ufm1' mRNA 930 982 963 10.22 10.61 11.23 13.34 13.09 13.03 10.68666667 13.15333333 1398 1340 1322 958.3333333 1353.333333 1.19E-08 0.485207038 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007420///brain development+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042308///negative regulation of protein import into nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0061709///reticulophagy+++GO:0071569///protein ufmylation+++GO:1990592///protein K69-linked ufmylation 67891 67891 'Rpl4' mRNA 8534 8573 8030 353.76 349.96 352.95 391.38 372.16 395.11 352.2233333 386.2166667 10849 10083 10606 8379 10512.66667 1.60E-10 0.315662532 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0031672///A band+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding GO:0006412///translation+++GO:0045773///positive regulation of axon extension+++GO:0050772///positive regulation of axonogenesis 67892 67892 'Coa6' mRNA 358 330 337 32.48 29.69 32.45 27.67 28.1 27.52 31.54 27.76333333 349 345 335 341.6666667 343 0.976471063 -0.00657737 04714///Thermogenesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0045277///respiratory chain complex IV GO:0005507///copper ion binding GO:0008535///respiratory chain complex IV assembly+++GO:0042774///plasma membrane ATP synthesis coupled electron transport+++GO:0042775///mitochondrial ATP synthesis coupled electron transport 67893 67893 'Tmem86a' mRNA 851 932 877 27.4 29.58 29.96 77.58 74.74 76.72 28.98 76.34666667 2769 2604 2650 886.6666667 2674.333333 4.67E-103 1.580587059 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0047408///alkenylglycerophosphocholine hydrolase activity+++GO:0047409///alkenylglycerophosphoethanolamine hydrolase activity 67894 67894 'Dennd10' mRNA 1080 1126 1131 25.62 26.34 28.55 22.95 24.19 22.66 26.83666667 23.26666667 1112 1146 1068 1112.333333 1108.666667 0.88195652 -0.017435044 GO:0005768///endosome+++GO:0005770///late endosome GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0050790///regulation of catalytic activity+++GO:2000641///regulation of early endosome to late endosome transport 67895 67895 'Ppa1' mRNA 604 538 617 28.32 24.9 30.69 41.57 48.44 39.35 27.97 43.12 1018 1157 932 586.3333333 1035.666667 1.05E-11 0.807222115 00190///Oxidative phosphorylation GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0004427///inorganic diphosphatase activity+++GO:0016462///pyrophosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006796///phosphate-containing compound metabolic process 67896 67896 'Ccdc80' mRNA 2321 2471 2396 36.32 37.98 39.77 63.61 63.09 62.24 38.02333333 62.98 4690 4567 4454 2396 4570.333333 1.78E-48 0.919140671 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix GO:0001968///fibronectin binding+++GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding GO:0009617///response to bacterium+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030198///extracellular matrix organization 67897 67897 'Rnmt' mRNA 559 615 593 11.99 12.85 13.1 15.65 16.02 14.8 12.64666667 15.49 789 778 732 589 766.3333333 7.13E-04 0.367254141 03015///mRNA surveillance pathway GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005845///mRNA cap binding complex+++GO:0031533///mRNA cap methyltransferase complex+++GO:0043235///receptor complex GO:0003723///RNA binding+++GO:0004482///mRNA (guanine-N7-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0032259///methylation+++GO:0106005///RNA 5'-cap (guanine-N7)-methylation+++GO:1990830///cellular response to leukemia inhibitory factor 67898 67898 'Pef1' mRNA 1482 1556 1478 56.18 58.17 59.44 58.21 53.97 55.08 57.93 55.75333333 1764 1596 1615 1505.333333 1658.333333 0.132966527 0.127100246 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0031463///Cul3-RING ubiquitin ligase complex "GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0048306///calcium-dependent protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development+++GO:0016567///protein ubiquitination+++GO:0048208///COPII vesicle coating+++GO:0051592///response to calcium ion+++GO:1902527///positive regulation of protein monoubiquitination 67899 67899 'Cmc1' mRNA 211.11 169.29 191.3 10.72 8.57 10.16 12.8 11.98 13.08 9.816666667 12.62 287.37 261.84 282.55 190.5666667 277.2533333 0.002792507 0.526057688 GO:0005739///mitochondrion GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 67900 67900 'Mtfp1' mRNA 156 140 170 6.68 5.91 7.72 7.05 8.22 7.48 6.77 7.583333333 189 215 194 155.3333333 199.3333333 0.1084806 0.345418808 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0000266///mitochondrial fission+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0007006///mitochondrial membrane organization+++GO:0014850///response to muscle activity 67902 67902 'Sumf2' mRNA 604.57 551.85 524.7 20.23 17.73 17.44 26.03 25.56 23.62 18.46666667 25.07 888.33 866.44 811.68 560.3733333 855.4833333 4.88E-09 0.600493591 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process 67903 67903 'Gipc1' mRNA 1097 1143 1173 39.48 40.57 44.86 53.59 58.06 54.25 41.63666667 55.3 1707 1807 1672 1137.666667 1728.666667 8.73E-12 0.590716207 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005903///brush border+++GO:0005938///cell cortex+++GO:0008021///synaptic vesicle+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005096///GTPase activator activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0017022///myosin binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding GO:0006605///protein targeting+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0014047///glutamate secretion+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031647///regulation of protein stability+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032467///positive regulation of cytokinesis+++GO:0043542///endothelial cell migration+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0048167///regulation of synaptic plasticity+++GO:0050790///regulation of catalytic activity+++GO:0098761///cellular response to interleukin-7+++GO:2000300///regulation of synaptic vesicle exocytosis 67905 67905 'Ppm1m' mRNA 965 957 826 30.85 30.16 28.02 25.04 27.42 29.35 29.67666667 27.27 900 962 1021 916 961 0.629635293 0.060872283 GO:0005634///nucleus GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation 67911 67911 'Zfp169' mRNA 316 348 302 1.8 1.74 1.77 1.28 0.84 0.84 1.77 0.986666667 271 174 186 322 210.3333333 6.39E-04 -0.62840536 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 67912 67912 '1600012H06Rik' mRNA 765.42 794.67 704 15.74 16.29 15.55 18.34 18.19 17.09 15.86 17.87333333 983.82 958.51 894 754.6966667 945.4433333 0.00106977 0.314703603 GO:0005576///extracellular region GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process 67914 67914 'Coq9' mRNA 2352 2336 2334 80.48 78.8 84.73 54.37 50.83 53.27 81.33666667 52.82333333 1826 1666 1731 2340.666667 1741 7.37E-10 -0.440190042 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane GO:0008289///lipid binding+++GO:0042803///protein homodimerization activity "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0006744///ubiquinone biosynthetic process" 67916 67916 'Plpp3' mRNA 4695 4992 4748 81.27 85.03 87.18 59.71 58.53 63.04 84.49333333 60.42666667 3969 3800 4058 4811.666667 3942.333333 1.17E-06 -0.299618781 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00600///Sphingolipid metabolism+++04072///Phospholipase D signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04975///Fat digestion and absorption+++05231///Choline metabolism in cancer GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0045121///membrane raft+++GO:0070971///endoplasmic reticulum exit site GO:0005178///integrin binding+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0042577///lipid phosphatase activity "GO:0001568///blood vessel development+++GO:0001702///gastrulation with mouth forming second+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0006672///ceramide metabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007229///integrin-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0030111///regulation of Wnt signaling pathway+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:0034109///homotypic cell-cell adhesion+++GO:0044328///canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration+++GO:0044329///canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion+++GO:0044330///canonical Wnt signaling pathway involved in positive regulation of wound healing+++GO:0046839///phospholipid dephosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060020///Bergmann glial cell differentiation+++GO:0060070///canonical Wnt signaling pathway+++GO:0098609///cell-cell adhesion+++GO:1902068///regulation of sphingolipid mediated signaling pathway" 67917 67917 'Zcchc3' mRNA 1165 1192 400 20.67 20.82 7.53 4.06 7.67 7.28 16.34 6.336666667 263 486 457 919 402 0.043081641 -1.176128425 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0009597///detection of virus+++GO:0032481///positive regulation of type I interferon production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0071360///cellular response to exogenous dsRNA+++GO:1900246///positive regulation of RIG-I signaling pathway 67920 67920 'Mak16' mRNA 313.63 343.28 307.92 9.7 10.46 10.1 13.82 17.08 13.71 10.08666667 14.87 513.78 619.79 493.36 321.61 542.31 8.15E-08 0.745659247 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0043231///intracellular membrane-bounded organelle" GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA 67921 67921 'Ube2f' mRNA 708 764 648 27.2 28.02 25.77 42.05 42.44 38.82 26.99666667 41.10333333 1214 1250 1118 706.6666667 1194 9.42E-16 0.747379737 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0019788///NEDD8 transferase activity+++GO:0061654///NEDD8 conjugating enzyme activity GO:0045116///protein neddylation 67922 67922 'Fam32a' mRNA 3433.19 3557.56 3252.04 59.37 60.53 59.65 51.21 54.74 49.7 59.85 51.88333333 3408 3557.48 3202.79 3414.263333 3389.423333 0.825826018 -0.021018801 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0008150///biological_process 67923 67923 'Eloc' mRNA 1040 1033 1093 49.35 46.85 56.46 67.76 79.41 71.94 50.88666667 73.03666667 1572 1727 1576 1055.333333 1625 2.42E-11 0.609911123 04066///HIF-1 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030891///VCB complex+++GO:0070449///elongin complex GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter 67928 67928 'Abca14' mRNA 1 2 4 0.01 0.04 0.04 0 0 0.02 0.03 0.006666667 0 0 1 2.333333333 0.333333333 0.299449079 -2.738812339 02010///ABC transporters GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0055085///transmembrane transport 67933 67933 'Hcfc2' mRNA 597.82 636.6 554.94 8.84 9.59 8.6 9.42 8.96 8.09 9.01 8.823333333 666.68 604.5 562.53 596.4533333 611.2366667 0.863090843 0.024972687 04212///Longevity regulating pathway - worm+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0035097///histone methyltransferase complex+++GO:0071339///MLL1 complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 67935 67935 'Ces5a' mRNA 0 1 3 0 0.03 0.09 0.08 0.1 0.03 0.04 0.07 3 4 1 1.333333333 2.666666667 0.685084116 0.957222626 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0080030///methyl indole-3-acetate esterase activity GO:0016042///lipid catabolic process 67936 67936 'Wdr55' mRNA 276 238 287 10.75 9.14 11.86 13.05 12.51 13.35 10.58333333 12.97 385 360 381 267 375.3333333 0.002297152 0.475903065 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006364///rRNA processing 67937 67937 'Tmem59l' mRNA 1629 1518 1553 64.76 59.41 65.42 10.38 9.91 9.67 63.19666667 9.986666667 301 279 271 1566.666667 283.6666667 5.21E-138 -2.478508718 GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 67938 67938 'Myl12b' mRNA 5447.36 5405.3 5455.3 376.92 370.09 400.53 442.71 471.88 454.66 382.5133333 456.4166667 7332.49 7615.9 7275.59 5435.986667 7407.993333 1.23E-12 0.434098146 04360///Axon guidance+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05132///Salmonella infection GO:0001725///stress fiber+++GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0099738///cell cortex region GO:0005509///calcium ion binding+++GO:0032036///myosin heavy chain binding+++GO:0046872///metal ion binding GO:0008360///regulation of cell shape 67939 67939 'Prorsd1' mRNA 438.82 492.97 450 12.13 13.45 13.2 14.51 14.74 15.87 12.92666667 15.04 604.02 602.99 641 460.5966667 616.0033333 5.00E-04 0.409404729 GO:0005575///cellular_component GO:0002161///aminoacyl-tRNA editing activity+++GO:0003674///molecular_function GO:0008150///biological_process+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 67941 67941 'Rps27l' mRNA 1315 1361 1558 212.22 220.76 267.72 369.51 404.76 416.34 233.5666667 396.87 2610 2778 2831 1411.333333 2739.666667 1.32E-23 0.941530115 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0008494///translation activator activity+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0046872///metal ion binding "GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0045727///positive regulation of translation" 67942 67942 'Atp5g2' mRNA 2461 2282 2096 280.85 258.94 253.88 328.87 327.9 332.26 264.5566667 329.6766667 3291 3191 3206 2279.666667 3229.333333 5.34E-14 0.492286805 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0033177///proton-transporting two-sector ATPase complex, proton-transporting domain+++GO:0034703///cation channel complex+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" GO:0008289///lipid binding+++GO:0015078///proton transmembrane transporter activity+++GO:0022834///ligand-gated channel activity GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0046931///pore complex assembly+++GO:1902600///proton transmembrane transport 67943 67943 'Mesd' mRNA 2745 2805.38 2630.62 50.17 50.46 51 51.52 50.34 51.4 50.54333333 51.08666667 3243 3095.18 3133.12 2727 3157.1 0.001407174 0.199879268 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0001503///ossification+++GO:0006457///protein folding+++GO:0006909///phagocytosis+++GO:0007498///mesoderm development+++GO:0016055///Wnt signaling pathway+++GO:0034394///protein localization to cell surface+++GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering 67945 67945 'Rpl41' mRNA 6638.06 6730.99 7708.42 1352.31 1376.55 1667.95 1294.14 1318.64 1518.56 1465.603333 1377.113333 7203.04 7110.33 8119.62 7025.823333 7477.663333 0.494307626 0.073689356 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0042788///polysomal ribosome GO:0003730///mRNA 3'-UTR binding+++GO:0003735///structural constituent of ribosome+++GO:0048027///mRNA 5'-UTR binding GO:0002181///cytoplasmic translation+++GO:0006412///translation 67946 67946 'Spata6' mRNA 239 267 246 5.46 6.04 6.1 10.13 8.77 9.88 5.866666667 9.593333333 507 429 473 250.6666667 469.6666667 6.39E-11 0.893244939 GO:0005576///extracellular region+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097224///sperm connecting piece GO:0032027///myosin light chain binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0044458///motile cilium assembly 67948 67948 'Fbxo28' mRNA 674 744 266 7.33 7.96 3.07 3.55 3.82 4.18 6.12 3.85 376 395 428 561.3333333 399.6666667 0.334896503 -0.48013249 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome" GO:0042802///identical protein binding GO:0000209///protein polyubiquitination 67949 67949 'Nifk' mRNA 650 634 658 19.66 18.9 21.11 26.84 26.9 25.34 19.89 26.36 1020 998 932 647.3333333 983.3333333 2.47E-09 0.589998306 GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)" 67951 67951 'Tubb6' mRNA 129 101 104 4.28 3.3 3.66 66.34 75.96 69.01 3.746666667 70.43666667 2298 2568 2313 111.3333333 2393 5.28E-305 4.416210917 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process 67952 67952 'Tomm20' mRNA 2778 2773 2556 29.77 29.22 29.05 32.39 31.9 31.18 29.34666667 31.82333333 3480 3348 3245 2702.333333 3357.666667 8.45E-07 0.302276214 GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0044233///Mitochondria-associated ER Membrane GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0051082///unfolded protein binding "GO:0006605///protein targeting+++GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0014850///response to muscle activity+++GO:0015031///protein transport+++GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0071806///protein transmembrane transport+++GO:1905242///response to 3,3',5-triiodo-L-thyronine" 67955 67955 'Sugt1' mRNA 1063 1136 1118 19.3 20.3 21.53 20.02 23.3 20.5 20.37666667 21.27333333 1269 1442 1258 1105.666667 1323 0.014239132 0.247318191 04621///NOD-like receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0003674///molecular_function+++GO:0051087///chaperone binding GO:0031647///regulation of protein stability+++GO:0043947///positive regulation by host of symbiont catalytic activity+++GO:0050821///protein stabilization 67956 67956 'Kmt5a' mRNA 422 392 382 7.71 6.95 7.49 10.43 9.99 9.28 7.383333333 9.9 607 566 525 398.6666667 566 5.35E-05 0.493688462 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0002039///p53 binding+++GO:0003714///transcription corepressor activity+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0018026///peptidyl-lysine monomethylation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051301///cell division" 67958 67958 'U2surp' mRNA 1563 1555 1667 10.65 10.41 12.06 9.85 8.7 8.86 11.04 9.136666667 1662 1436 1448 1595 1515.333333 0.402260808 -0.089508245 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005686///U2 snRNP GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006396///RNA processing+++GO:0008150///biological_process 67959 67959 'Puf60' mRNA 6045 6419 6390 185.39 194.47 207.9 143.45 155.8 148.07 195.92 149.1066667 5355 5673 5335 6284.666667 5454.333333 0.001828711 -0.216991544 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030054///cell junction GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing" 67963 67963 'Npc2' mRNA 3922 4025 3846 65.67 66.31 68.31 164.71 168.6 165.76 66.76333333 166.3566667 11319 11317 11031 3931 11222.33333 2.19E-181 1.501783328 04142///Lysosome+++04979///Cholesterol metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum GO:0015485///cholesterol binding+++GO:0019899///enzyme binding+++GO:0032934///sterol binding+++GO:0120020///intermembrane cholesterol transfer activity GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0009615///response to virus+++GO:0015918///sterol transport+++GO:0030301///cholesterol transport+++GO:0032366///intracellular sterol transport+++GO:0032367///intracellular cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0042632///cholesterol homeostasis+++GO:0120009///intermembrane lipid transfer 67966 67966 'Zcchc10' mRNA 179 203 191 8.67 9.71 9.81 12.15 12.93 11.21 9.396666667 12.09666667 288 299 257 191 281.3333333 0.001453044 0.546959437 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 67967 67967 'Pold3' mRNA 786 863 813 14.21 15.32 15.7 13.08 13.12 11.51 15.07666667 12.57 826 808 706 820.6666667 780 0.504631225 -0.085577072 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0043625///delta DNA polymerase complex "GO:0003887///DNA-directed DNA polymerase activity+++GO:0030674///protein binding, bridging" "GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006271///DNA strand elongation involved in DNA replication+++GO:0006281///DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0071897///DNA biosynthetic process+++GO:1904161///DNA synthesis involved in UV-damage excision repair" 67968 67968 'Ooep' mRNA 0 1 5 0 0.05 0.27 0.18 0.18 0.18 0.106666667 0.18 4 4 4 2 4 0.619994862 0.947766912 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0045179///apical cortex GO:0003723///RNA binding+++GO:0005515///protein binding GO:0001701///in utero embryonic development+++GO:0006468///protein phosphorylation+++GO:0007015///actin filament organization+++GO:0007566///embryo implantation+++GO:0009566///fertilization+++GO:0009880///embryonic pattern specification+++GO:0031297///replication fork processing+++GO:0032880///regulation of protein localization+++GO:0034622///cellular protein-containing complex assembly+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051293///establishment of spindle localization+++GO:0051302///regulation of cell division+++GO:0070201///regulation of establishment of protein localization+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2000781///positive regulation of double-strand break repair 67971 67971 'Tppp3' mRNA 274 284 290 16.7 17.28 19.05 32.67 27.76 31.66 17.67666667 30.69666667 605 505 569 282.6666667 559.6666667 8.49E-14 0.971240529 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016324///apical plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0097427///microtubule bundle GO:0003674///molecular_function+++GO:0015631///tubulin binding GO:0001578///microtubule bundle formation+++GO:0007566///embryo implantation+++GO:0008150///biological_process+++GO:0032273///positive regulation of protein polymerization+++GO:0046697///decidualization+++GO:0046785///microtubule polymerization 67972 67972 'Atp2b1' mRNA 7567.77 7572.19 6724.55 55.73 54.74 52.68 40.69 37.41 41.04 54.38333333 39.71333333 6346.91 5712.76 6212.08 7288.17 6090.583333 1.47E-06 -0.26953145 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04925///Aldosterone synthesis and secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04970///Salivary secretion+++04972///Pancreatic secretion+++04978///Mineral absorption GO:0001772///immunological synapse+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032590///dendrite membrane+++GO:0032591///dendritic spine membrane+++GO:0032809///neuronal cell body membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0099059///integral component of presynaptic active zone membrane GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding+++GO:1905056///calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration GO:0001818///negative regulation of cytokine production+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0003407///neural retina development+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007420///brain development+++GO:0007568///aging+++GO:0008217///regulation of blood pressure+++GO:0009409///response to cold+++GO:0030501///positive regulation of bone mineralization+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051928///positive regulation of calcium ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071305///cellular response to vitamin D+++GO:0071386///cellular response to corticosterone stimulus+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:1900076///regulation of cellular response to insulin stimulus+++GO:1901660///calcium ion export+++GO:1990034///calcium ion export across plasma membrane 67973 67973 'Mphosph10' mRNA 399 412 389 10.21 10.39 10.56 12.8 13.66 12.33 10.38666667 12.93 575 599 536 400 570 3.60E-05 0.499876058 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0032040///small-subunit processome+++GO:0034457///Mpp10 complex GO:0006364///rRNA processing+++GO:0010923///negative regulation of phosphatase activity+++GO:0042254///ribosome biogenesis 67974 67974 'Ccny' mRNA 664 676 581 6.96 7.03 6.63 6.87 8.97 8.23 6.873333333 8.023333333 768 989 889 640.3333333 882 1.66E-04 0.455091017 GO:0000308///cytoplasmic cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0016055///Wnt signaling pathway+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045859///regulation of protein kinase activity+++GO:0051301///cell division+++GO:0060828///regulation of canonical Wnt signaling pathway 67976 67976 'Trabd' mRNA 944 953 808 22.06 21.92 20.01 25.98 24.27 24.04 21.33 24.76333333 1281 1166 1147 901.6666667 1198 7.52E-06 0.400125087 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67978 67978 'Tctn2' mRNA 1032 1048 976 20.87 20.86 20.94 10.18 9.92 9.57 20.89 9.89 579 551 527 1018.666667 552.3333333 2.03E-21 -0.894515997 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:1904491///protein localization to ciliary transition zone 67979 67979 'Atad1' mRNA 1642 1832 1734 32.21 35.36 36.09 35.98 34.4 32.44 34.55333333 34.27333333 2110 1970 1843 1736 1974.333333 0.045999505 0.172691249 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity "GO:0002092///positive regulation of receptor internalization+++GO:0007612///learning+++GO:0007613///memory+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization" 67980 67980 'Gnpda2' mRNA 1377 1457 1342 41.7 43.87 43.41 32.22 30.95 30.7 42.99333333 31.29 1206 1132 1106 1392 1148 4.27E-04 -0.289661478 00520///Amino sugar and nucleotide sugar metabolism GO:0005737///cytoplasm GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0005975///carbohydrate metabolic process+++GO:0006043///glucosamine catabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006046///N-acetylglucosamine catabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0019262///N-acetylneuraminate catabolic process 67983 67983 'Pdzd9' mRNA 22.41 16.21 8.19 0.54 0.38 0.21 0.17 0.15 0.18 0.376666667 0.166666667 8.17 7.09 8.17 15.60333333 7.81 0.233675675 -0.998630729 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 67988 67988 'Tmx3' mRNA 1303 1481 1449 15.15 16.93 17.87 17.35 16.23 18.93 16.65 17.50333333 1718 1570 1815 1411 1701 0.006716511 0.256100659 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0016972///thiol oxidase activity GO:0018171///peptidyl-cysteine oxidation 67991 67991 'Nacc2' mRNA 6401 6799 6223 51.81 54.06 53.57 32.86 30.34 31.85 53.14666667 31.68333333 4628 4202 4351 6474.333333 4393.666667 2.98E-25 -0.571110208 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0044877///protein-containing complex binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0031503///protein-containing complex localization+++GO:0034629///cellular protein-containing complex localization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051260///protein homooligomerization+++GO:1900477///negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage" 67993 67993 'Nudt12' mRNA 633 648 633 9.63 9.75 10.33 5.67 5.34 4.67 9.903333333 5.226666667 429 395 342 638 388.6666667 2.46E-09 -0.728114708 00760///Nicotinate and nicotinamide metabolism+++04146///Peroxisome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol GO:0000210///NAD+ diphosphatase activity+++GO:0000287///magnesium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0046872///metal ion binding+++GO:1990174///phosphodiesterase decapping endonuclease activity GO:0006402///mRNA catabolic process+++GO:0006734///NADH metabolic process+++GO:0006742///NADP catabolic process+++GO:0019677///NAD catabolic process+++GO:0032922///circadian regulation of gene expression 67994 67994 'Mrps11' mRNA 481 511 457 29.17 30.65 29.41 33.64 34.68 33.99 29.74333333 34.10333333 636 639 621 483 632 7.67E-04 0.377511307 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0022627///cytosolic small ribosomal subunit GO:0003735///structural constituent of ribosome+++GO:0048027///mRNA 5'-UTR binding+++GO:0070181///small ribosomal subunit rRNA binding "GO:0000028///ribosomal small subunit assembly+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006412///translation+++GO:0032543///mitochondrial translation" 67996 67996 'Srsf6' mRNA 2141 2220 2275 32.8 33.46 36.97 40.61 40.05 39.7 34.41 40.12 3051 2939 2888 2212 2959.333333 2.06E-08 0.406152521 03040///Spliceosome+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010629///negative regulation of gene expression+++GO:0010837///regulation of keratinocyte proliferation+++GO:0032868///response to insulin+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0061041///regulation of wound healing+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process" 67997 67997 'Ddx59' mRNA 289 283 292 7.37 7.2 7.86 5.96 5 5.86 7.476666667 5.606666667 272 220 256 288 249.3333333 0.212193871 -0.222325224 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding 67998 67998 'Retreg3' mRNA 550 564 426 9.16 9.17 7.6 9.38 7.13 9.2 8.643333333 8.57 648 484 619 513.3333333 583.6666667 0.251097854 0.17653213 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0010976///positive regulation of neuron projection development+++GO:0061709///reticulophagy 68001 68001 'Cfap298' mRNA 1157 1189 1166 58.66 59.82 63.94 46 45.2 44.71 60.80666667 45.30333333 1004 965 949 1170.666667 972.6666667 0.001666151 -0.279862103 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003352///regulation of cilium movement+++GO:0060271///cilium assembly 68002 68002 'Sdhaf4' mRNA 490 532 497 53.54 57.77 57.63 57.29 61.55 48.29 56.31333333 55.71 599 626 487 506.3333333 570.6666667 0.273744127 0.161029032 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008047///enzyme activator activity GO:0034553///mitochondrial respiratory chain complex II assembly+++GO:0045087///innate immune response+++GO:0045333///cellular respiration+++GO:1904231///positive regulation of succinate dehydrogenase activity 68010 68010 'Bambi' mRNA 561 582 533 15.5 15.9 15.73 11.63 11.89 12.67 15.71 12.06333333 481 479 506 558.6666667 488.6666667 0.09819051 -0.20377626 04310///Wnt signaling pathway+++04350///TGF-beta signaling pathway GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005109///frizzled binding "GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016477///cell migration+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090263///positive regulation of canonical Wnt signaling pathway" 68011 68011 'Snrpg' mRNA 637 572.09 707 166.34 150.79 196.28 195.74 214.58 205.29 171.1366667 205.2033333 846 897 851 638.6966667 864.6666667 6.20E-04 0.421217537 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005683///U7 snRNP+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034709///methylosome+++GO:0034719///SMN-Sm protein complex+++GO:0043186///P granule+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0097526///spliceosomal tri-snRNP complex+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:1990446///U1 snRNP binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 68014 68014 'Zwilch' mRNA 27.04 30.34 31.36 0.54 0.59 0.66 1.56 1.97 2.47 0.596666667 2 90.64 111.59 138.65 29.58 113.6266667 1.93E-09 1.935107409 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:1990423///RZZ complex" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division+++GO:0072413///signal transduction involved in mitotic cell cycle checkpoint 68015 68015 'Trap1' mRNA 1611 1748 1550 39.37 42.07 40.19 38.72 38.11 38.73 40.54333333 38.52 1822 1751 1764 1636.333333 1779 0.176409497 0.109910869 05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0009386///translational attenuation+++GO:1901856///negative regulation of cellular respiration+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide 68016 68016 'Cavin4' mRNA 1 2 1 0.03 0.05 0.03 0.05 0 0.02 0.036666667 0.023333333 2 0 1 1.333333333 1 0.879088955 -0.431788456 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0042383///sarcolemma GO:0005096///GTPase activator activity GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0035023///regulation of Rho protein signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0055003///cardiac myofibril assembly 68017 68017 'Mrm2' mRNA 260 266 260 10.71 10.81 11.36 10.72 13.71 9.05 10.96 11.16 299 373 244 262 305.3333333 0.310550658 0.210252591 GO:0005730///nucleolus+++GO:0005739///mitochondrion GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0008650///rRNA (uridine-2'-O-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0031167///rRNA methylation+++GO:0032259///methylation 68018 68018 'Cert1' mRNA 644.13 613.54 558 5.87 5.36 5.37 6.45 6.62 6.64 5.533333333 6.57 829.69 809.64 808.86 605.2233333 816.0633333 2.98E-05 0.420280818 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0008289///lipid binding+++GO:0016301///kinase activity+++GO:0042802///identical protein binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0097001///ceramide binding+++GO:0120017///intermembrane ceramide transfer activity+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0000902///cell morphogenesis+++GO:0001701///in utero embryonic development+++GO:0003007///heart morphogenesis+++GO:0006672///ceramide metabolic process+++GO:0006869///lipid transport+++GO:0006936///muscle contraction+++GO:0007029///endoplasmic reticulum organization+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0016310///phosphorylation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0055088///lipid homeostasis+++GO:0070584///mitochondrion morphogenesis+++GO:0120009///intermembrane lipid transfer+++GO:0120012///intermembrane sphingolipid transfer+++GO:1902389///ceramide 1-phosphate transport 68020 68020 'Coa8' mRNA 577.73 483.35 631.42 35.37 29.25 40.65 38.21 34.16 33.2 35.09 35.19 729.96 612.34 612.16 564.1666667 651.4866667 0.223749047 0.188905164 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0099617///matrix side of mitochondrial inner membrane GO:0003674///molecular_function GO:0000302///response to reactive oxygen species+++GO:0006915///apoptotic process+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0050821///protein stabilization+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1904960///positive regulation of cytochrome-c oxidase activity 68021 68021 'Bphl' mRNA 1447 1370 1392 74.85 70.24 76.3 37.92 42.62 39.92 73.79666667 40.15333333 846 925 866 1403 879 2.01E-14 -0.686242457 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0047658///alpha-amino-acid esterase activity 68023 68023 'Pdf' mRNA 867 935 872 33.21 35.32 35.44 33.41 32.98 32.23 34.65666667 32.87333333 1002 965 935 891.3333333 967.3333333 0.315678357 0.106261159 GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0042586///peptide deformylase activity+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0008284///positive regulation of cell proliferation+++GO:0018206///peptidyl-methionine modification+++GO:0031365///N-terminal protein amino acid modification+++GO:0043686///co-translational protein modification 68024 68024 'H2bc4' mRNA 1735.36 1749.08 1705.94 168.37 167.87 175.08 294.73 319.02 300.92 170.44 304.89 3482.53 3671.58 3433.88 1730.126667 3529.33 2.94E-50 1.017212282 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity GO:0002227///innate immune response in mucosa+++GO:0006334///nucleosome assembly+++GO:0019731///antibacterial humoral response+++GO:0050830///defense response to Gram-positive bacterium+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide 68026 68026 'Pclaf' mRNA 36.31 66.05 56.64 0.85 1.52 1.41 12.68 12.44 11.64 1.26 12.25333333 622.07 596 552.91 53 590.3266667 3.50E-78 3.473552827 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm GO:0003682///chromatin binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007098///centrosome cycle+++GO:0009411///response to UV+++GO:0019985///translesion synthesis+++GO:0051726///regulation of cell cycle 68027 68027 'Tmem178' mRNA 55 43 49 1.88 1.45 1.78 7.3 8.15 8.78 1.703333333 8.076666667 245 267 285 49 265.6666667 1.46E-28 2.427653047 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0045671///negative regulation of osteoclast differentiation+++GO:0051480///regulation of cytosolic calcium ion concentration 68028 68028 'Rpl22l1' mRNA 1029 908 985 181.6 160.49 184.62 191.97 198.94 195.74 175.57 195.55 1237 1243 1213 974 1231 6.99E-04 0.324741265 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation 68031 68031 'Rnf146' mRNA 1038.22 1079.62 806.23 14.03 14.41 11.58 8.82 8.54 11.3 13.34 9.553333333 756.42 710.42 936.12 974.69 800.9866667 0.025549865 -0.289193311 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0072572///poly-ADP-D-ribose binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death 68032 68032 'Emc4' mRNA 2149.38 2222.42 2174.59 141.81 145.18 152.52 123.72 140.49 126.64 146.5033333 130.2833333 2146.58 2379.99 2122.66 2182.13 2216.41 0.918573815 0.010883173 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0006915///apoptotic process+++GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 68033 68033 'Cox19' mRNA 581 595 554 52.9 53.73 53.53 65.81 68.09 62.74 53.38666667 65.54666667 827 833 761 576.6666667 807 4.15E-06 0.473798262 04714///Thermogenesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol GO:0003674///molecular_function GO:0006878///cellular copper ion homeostasis+++GO:0033617///mitochondrial respiratory chain complex IV assembly 68034 68034 'Fam122a' mRNA 201 183 95 6.88 6.18 3.45 3.28 5.56 4.71 5.503333333 4.516666667 110 182 153 159.6666667 148.3333333 0.792126085 -0.100162189 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity GO:0030307///positive regulation of cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0044818///mitotic G2/M transition checkpoint 68035 68035 'Rbm42' mRNA 2131 2098 2023 72.73 70.58 73.24 68.22 69.9 68.01 72.18333333 68.71 2297 2297 2216 2084 2270 0.139249009 0.111835484 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0048025///negative regulation of mRNA splicing, via spliceosome" 68036 68036 'Zfp706' mRNA 5350.91 5621.57 4914.08 65.07 67.23 63.39 48.63 53.77 51.69 65.23 51.36333333 4603.02 4972.15 4739.26 5295.52 4771.476667 0.016018547 -0.159183096 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006417///regulation of translation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1902455///negative regulation of stem cell population maintenance" 68038 68038 'Chid1' mRNA 1047.34 1157.03 987.43 19.79 20.97 21.51 20.18 17.34 19.86 20.75666667 19.12666667 1184.08 998.82 1117.75 1063.933333 1100.216667 0.767776765 0.037019372 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005802///trans-Golgi network GO:0008061///chitin binding+++GO:0070492///oligosaccharide binding GO:0002376///immune system process+++GO:0005975///carbohydrate metabolic process+++GO:0045087///innate immune response+++GO:1900016///negative regulation of cytokine production involved in inflammatory response 68039 68039 'Nmb' mRNA 108 103 114 11.23 10.62 12.57 8.27 8.13 8.01 11.47333333 8.136666667 91 87 85 108.3333333 87.66666667 0.255863442 -0.31979876 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0043005///neuron projection GO:0005184///neuropeptide hormone activity+++GO:0031710///neuromedin B receptor binding GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007218///neuropeptide signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046887///positive regulation of hormone secretion+++GO:0046888///negative regulation of hormone secretion+++GO:0050482///arachidonic acid secretion 68040 68040 'Zfp593' mRNA 224 228 221 6.46 6.48 6.76 7 7.58 6.3 6.566666667 6.96 279 295 243 224.3333333 272.3333333 0.137210546 0.268186494 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding 68041 68041 'Mid1ip1' mRNA 2624 2716 2674 72.42 73.85 78.29 62.73 65.68 64.86 74.85333333 64.42333333 2613 2671 2615 2671.333333 2633 0.727849727 -0.03306553 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding GO:0006629///lipid metabolic process+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0046890///regulation of lipid biosynthetic process+++GO:0051258///protein polymerization+++GO:0051351///positive regulation of ligase activity 68043 68043 'Eef1akmt1' mRNA 407 406 401 31.9 31.52 33.36 39.84 42.28 39.73 32.26 40.61666667 582 602 561 404.6666667 581.6666667 1.70E-05 0.511734548 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity GO:0018022///peptidyl-lysine methylation+++GO:0032259///methylation 68044 68044 'Chac2' mRNA 218 238 224 9.95 10.7 10.78 5.54 6.01 6.46 10.47666667 6.003333333 140 148 158 226.6666667 148.6666667 9.17E-04 -0.619620494 00480///Glutathione metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0016829///lyase activity+++GO:0061928///glutathione specific gamma-glutamylcyclotransferase activity GO:0006751///glutathione catabolic process 68045 68045 'Rtraf' mRNA 1186.28 1260.36 1201.28 46.38 48.6 49.82 62.43 63.37 63.45 48.26666667 63.08333333 1834.28 1816.88 1803.77 1215.973333 1818.31 6.81E-14 0.568519674 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0072669///tRNA-splicing ligase complex+++GO:0072686///mitotic spindle GO:0000993///RNA polymerase II complex binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding "GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006469///negative regulation of protein kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II" 68046 68046 '2700062C07Rik' mRNA 393 408 366 24.16 24.8 23.88 17.75 18.26 17.59 24.28 17.86666667 331 332 317 389 326.6666667 0.066218566 -0.262308114 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68047 68047 'Mpnd' mRNA 201 218 200 6.86 7.33 7.24 9.21 8.12 9.79 7.143333333 9.04 310 267 319 206.3333333 298.6666667 0.001562616 0.521585946 GO:0003713///transcription coactivator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0070122///isopeptidase activity GO:0006338///chromatin remodeling+++GO:0006508///proteolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II 68048 68048 'Aen' mRNA 546 511 530 5.95 5.47 6.16 11.87 10.47 11.58 5.86 11.30666667 1250 1079 1185 529 1171.333333 4.76E-31 1.133200051 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031965///nuclear membrane GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 68050 68050 'Akirin1' mRNA 1428 1599 1435 33.73 37.19 35.95 44.59 41.64 42.96 35.62333333 43.06333333 2171 1980 2025 1487.333333 2058.666667 1.02E-09 0.45729831 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane GO:0003712///transcription coregulator activity GO:0010592///positive regulation of lamellipodium assembly+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0014839///myoblast migration involved in skeletal muscle regeneration+++GO:0045663///positive regulation of myoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation+++GO:1902725///negative regulation of satellite cell differentiation 68051 68051 'Nutf2' mRNA 2054 1960 1968 56.02 52.63 56.9 62.29 65.37 66.77 55.18333333 64.81 2619 2691 2716 1994 2675.333333 6.10E-09 0.4122643 GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0044613///nuclear pore central transport channel GO:0017056///structural constituent of nuclear pore+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0140142///nucleocytoplasmic carrier activity GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0051028///mRNA transport+++GO:0090204///protein localization to nuclear pore+++GO:1904046///negative regulation of vascular endothelial growth factor production 68052 68052 'Rps13' mRNA 2214.59 2024.42 2190.31 295.42 269.08 310.16 392.68 424.87 422.89 291.5533333 413.48 3356.55 3528.72 3482.6 2143.106667 3455.956667 4.93E-19 0.676382908 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0048027///mRNA 5'-UTR binding+++GO:0070181///small ribosomal subunit rRNA binding+++GO:1990932///5.8S rRNA binding GO:0006412///translation+++GO:0033119///negative regulation of RNA splicing 68053 68053 'Ubxn2b' mRNA 399 393 400 4.51 4.37 4.8 4.83 4.02 4.65 4.56 4.5 492 400 458 397.3333333 450 0.270660943 0.165444675 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome GO:0043130///ubiquitin binding GO:0000045///autophagosome assembly+++GO:0000132///establishment of mitotic spindle orientation+++GO:0007030///Golgi organization+++GO:0031468///nuclear envelope reassembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0046604///positive regulation of mitotic centrosome separation+++GO:0061025///membrane fusion+++GO:1904780///negative regulation of protein localization to centrosome 68055 68055 'Dmac2l' mRNA 590 591 646 21.2 21.4 27.56 12.92 11.59 14.78 23.38666667 13.09666667 399 351 396 609 382 4.88E-08 -0.688229492 "GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" GO:0046872///metal ion binding GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport 68058 68058 'Chd1l' mRNA 404.66 431.99 444.64 7.42 7.92 8.62 7.91 7.63 7.43 7.986666667 7.656666667 496.46 462.72 450.11 427.0966667 469.7633333 0.411262604 0.12451776 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0006281///DNA repair+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032508///DNA duplex unwinding 68059 68059 'Tm9sf2' mRNA 7049 7389 7035 126.11 130.11 133.45 113.15 115.04 109.62 129.89 112.6033333 7275 7226 6824 7157.666667 7108.333333 0.782061644 -0.021934753 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0072657///protein localization to membrane 68066 68066 'Slc25a39' mRNA 4785 4830 4754 171.03 169.14 179.53 191.13 188.03 185.82 173.2333333 188.3266667 6135 5935 5821 4789.666667 5963.666667 1.46E-07 0.303678798 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006783///heme biosynthetic process 68067 68067 'Mrnip' mRNA 238.88 249.61 233.35 10.53 11.13 10.69 10.4 10.36 8.98 10.78333333 9.913333333 323.06 311.27 280.39 240.6133333 304.9066667 0.041253204 0.332476405 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030870///Mre11 complex GO:0003674///molecular_function+++GO:0003682///chromatin binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0008150///biological_process+++GO:0010212///response to ionizing radiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0071168///protein localization to chromatin+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 68070 68070 'Pdzd2' mRNA 570 560 554 2.69 2.61 2.8 2.33 2.22 2.32 2.7 2.29 564 526 547 561.3333333 545.6666667 0.725652483 -0.053281541 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0034451///centriolar satellite+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045177///apical part of cell 68073 68073 'Atpsckmt' mRNA 603.44 642.22 608.28 12.49 12.48 13.55 14.66 16.53 17.35 12.84 16.18 582.05 637.67 633.28 617.98 617.6666667 0.939175627 -0.011585616 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031966///mitochondrial membrane GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity "GO:0018022///peptidyl-lysine methylation+++GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation+++GO:1904058///positive regulation of sensory perception of pain+++GO:1905273///positive regulation of proton-transporting ATP synthase activity, rotational mechanism+++GO:1905706///regulation of mitochondrial ATP synthesis coupled proton transport" 68075 68075 'Lurap1' mRNA 448 441 409 18.7 18.16 18.11 14.83 14.56 16.12 18.32333333 15.17 408 391 429 432.6666667 409.3333333 0.56368142 -0.090743929 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042641///actomyosin+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0001819///positive regulation of cytokine production+++GO:0016477///cell migration+++GO:0031032///actomyosin structure organization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling 68077 68077 'Nop53' mRNA 2789 2836 2943 105.19 105.48 117.75 78 86.63 82.96 109.4733333 82.53 2376 2575 2445 2856 2465.333333 0.005620491 -0.225110501 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0033553///rDNA heterochromatin+++GO:0043231///intracellular membrane-bounded organelle GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0008097///5S rRNA binding+++GO:0042802///identical protein binding GO:0000027///ribosomal large subunit assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001932///regulation of protein phosphorylation+++GO:0006281///DNA repair+++GO:0006364///rRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0031333///negative regulation of protein complex assembly+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0039535///regulation of RIG-I signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0042981///regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0051726///regulation of cell cycle+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0071456///cellular response to hypoxia+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902570///protein localization to nucleolus+++GO:1903006///positive regulation of protein K63-linked deubiquitination+++GO:1903715///regulation of aerobic respiration+++GO:1990173///protein localization to nucleoplasm 68079 68079 'Pdcd2l' mRNA 412 486 462 19.34 22.44 22.84 21.27 24.13 22.32 21.54 22.57333333 516 577 526 453.3333333 539.6666667 0.08395129 0.239927419 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0008150///biological_process 68080 68080 'Gpn3' mRNA 651 680 673 27.69 28.53 30.37 23.4 19.47 21.71 28.86333333 21.52666667 632 513 567 668 570.6666667 0.046901787 -0.241398777 GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity 68082 68082 'Dusp19' mRNA 463 387 334 18.77 15.48 14.37 10.31 10.75 9.89 16.20666667 10.31666667 292 297 271 394.6666667 286.6666667 0.002453469 -0.469052946 GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0008579///JUN kinase phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0030295///protein kinase activator activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding GO:0000188///inactivation of MAPK activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0006470///protein dephosphorylation+++GO:0007254///JNK cascade+++GO:0016311///dephosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0043405///regulation of MAP kinase activity+++GO:0043409///negative regulation of MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043508///negative regulation of JUN kinase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0046329///negative regulation of JNK cascade+++GO:0046330///positive regulation of JNK cascade 68083 68083 'Pak1ip1' mRNA 787 837 794 25.96 27.21 27.79 32.98 30.11 32.27 26.98666667 31.78666667 1149 1024 1088 806 1087 5.09E-06 0.418929747 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004622///lysophospholipase activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008283///cell proliferation+++GO:0009968///negative regulation of signal transduction+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0046475///glycerophospholipid catabolic process+++GO:0060021///roof of mouth development+++GO:0070291///N-acylethanolamine metabolic process+++GO:1901796///regulation of signal transduction by p53 class mediator 68087 68087 'Dcakd' mRNA 1376 1328 1009 45.09 42.95 35.31 33.43 38.81 35.01 41.11666667 35.75 1178 1311 1175 1237.666667 1221.333333 0.863090843 -0.02418734 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004140///dephospho-CoA kinase activity+++GO:0005524///ATP binding GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation 68089 68089 'Arpc4' mRNA 2225.39 2118.22 2096.69 55.07 51.62 55.08 120.54 114.64 118.03 53.92333333 117.7366667 5596.9 5198.5 5308.05 2146.766667 5367.816667 9.61E-107 1.30992491 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0015629///actin cytoskeleton+++GO:0035861///site of double-strand break+++GO:0042995///cell projection "GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0019899///enzyme binding+++GO:0030674///protein binding, bridging+++GO:0051015///actin filament binding" GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation 68090 68090 'Yif1a' mRNA 1400 1461 1437 55.45 57.08 60.38 58.1 56.29 59.77 57.63666667 58.05333333 1685 1593 1677 1432.666667 1651.666667 0.019512735 0.192458419 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 68092 68092 'Ncbp2' mRNA 1437 1426 1441 40.08 39.19 42.64 38.41 39.12 36.75 40.63666667 38.09333333 1583 1574 1466 1434.666667 1541 0.343156292 0.090390191 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005845///mRNA cap binding complex+++GO:0005846///nuclear cap binding complex+++GO:0034518///RNA cap binding complex GO:0000339///RNA cap binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0017069///snRNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006408///snRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0098789///pre-mRNA cleavage required for polyadenylation" 68094 68094 'Smarcc2' mRNA 3365 3467 3220 36.66 37.4 37.33 25.27 24.56 23.37 37.13 24.4 2622 2474 2368 3350.666667 2488 2.64E-12 -0.441112314 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 68095 68095 'Ociad1' mRNA 4052.8 4031.08 3157.64 143.56 138.51 117.8 135.12 124.74 134.02 133.29 131.2933333 4371.3 3987.17 4231.25 3747.173333 4196.573333 0.048835541 0.156094552 GO:0005739///mitochondrion+++GO:0005768///endosome GO:0005515///protein binding GO:2000736///regulation of stem cell differentiation 68097 68097 'Dynll2' mRNA 343 325 128 7.74 7.21 3.23 2.49 2.14 2.69 6.06 2.44 127 105 126 265.3333333 119.3333333 3.97E-05 -1.147375613 04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0014069///postsynaptic density+++GO:0030286///dynein complex+++GO:0031475///myosin V complex+++GO:0097731///9+0 non-motile cilium+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding+++GO:0097110///scaffold protein binding "GO:0007017///microtubule-based process+++GO:0060271///cilium assembly+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed" 68098 68098 'Rchy1' mRNA 1312.1 1255.87 1197.66 37.11 34.93 35.91 35.71 38.66 38.49 35.98333333 37.62 1451 1530.86 1511.99 1255.21 1497.95 0.003629143 0.244648224 04115///p53 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05162///Measles GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0002039///p53 binding+++GO:0005102///signaling receptor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination 68099 68099 'Cibar1' mRNA 555.99 561.61 544.96 20.06 19.78 20.29 18.35 19.66 18.31 20.04333333 18.77333333 593.5 639.71 575.84 554.1866667 603.0166667 0.40852141 0.111199947 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030061///mitochondrial crista+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0005515///protein binding+++GO:0005543///phospholipid binding GO:0007007///inner mitochondrial membrane organization+++GO:0030030///cell projection organization+++GO:0035108///limb morphogenesis+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060271///cilium assembly+++GO:0061024///membrane organization+++GO:0097749///membrane tubulation 68106 68106 'Nt5c3b' mRNA 1191.37 1222.36 1129.33 48.84 49.12 48.91 33.08 34.78 38.44 48.95666667 35.43333333 907.21 928.27 1007.24 1181.02 947.5733333 3.20E-04 -0.328098837 00240///Pyrimidine metabolism GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation 68107 68107 'Cntd1' mRNA 41.82 52.71 38.3 1.06 1.31 1.03 0.82 0.81 1.15 1.133333333 0.926666667 37.15 35.91 50.79 44.27666667 41.28333333 0.844715313 -0.109946533 GO:0035861///site of double-strand break GO:0003674///molecular_function GO:0007131///reciprocal meiotic recombination+++GO:0007283///spermatogenesis 68112 68112 'Entr1' mRNA 1760.93 1747.32 1006.18 49.05 48.54 30.04 30.77 39.29 38.03 42.54333333 36.03 1251.43 1573.13 1506.56 1504.81 1443.706667 0.866193436 -0.056563787 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0030904///retromer complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0032456///endocytic recycling+++GO:0032465///regulation of cytokinesis+++GO:0045724///positive regulation of cilium assembly+++GO:0051301///cell division+++GO:1903566///positive regulation of protein localization to cilium 68114 68114 'Pwwp3a' mRNA 1204 1307 1150 25.06 26.47 25.16 16.92 16.52 15.93 25.56333333 16.45666667 939 895 853 1220.333333 895.6666667 1.47E-07 -0.456953357 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031491///nucleosome binding GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus 68115 68115 'Maip1' mRNA 287.77 318.79 281.2 4.34 4.73 4.5 5.46 5.46 5.58 4.523333333 5.5 416.58 407 412.25 295.92 411.9433333 6.33E-04 0.468533493 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix GO:0043022///ribosome binding GO:0007007///inner mitochondrial membrane organization+++GO:0032979///protein insertion into mitochondrial inner membrane from matrix side+++GO:0036444///calcium import into the mitochondrion+++GO:0051204///protein insertion into mitochondrial membrane+++GO:0051560///mitochondrial calcium ion homeostasis 68117 68117 'Apool' mRNA 273 277 327 12.36 12.27 15.76 19.91 18.52 17.91 13.46333333 18.78 502 458 437 292.3333333 465.6666667 9.05E-06 0.654780236 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0061617///MICOS complex GO:0042407///cristae formation 68118 68118 'Atg101' mRNA 795 806 859 39.44 39.41 45.25 46.34 52.68 44.22 41.36666667 47.74666667 1078 1191 989 820 1086 3.76E-04 0.39198936 04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0000045///autophagosome assembly+++GO:0006914///autophagy 68119 68119 'Cmtm3' mRNA 408 408 419 15.03 14.71 16.4 59.02 66.65 64.56 15.38 63.41 1839 2024 1949 411.6666667 1937.333333 8.42E-125 2.223010359 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane GO:0005125///cytokine activity+++GO:0005515///protein binding GO:0001835///blastocyst hatching+++GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0050861///positive regulation of B cell receptor signaling pathway 68121 68121 'Cep70' mRNA 493.82 555.44 482.18 7.31 8 7.26 5.37 4.78 5.8 7.523333333 5.316666667 407.12 343.99 415.1 510.48 388.7366667 0.002166381 -0.404467728 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0042802///identical protein binding+++GO:0043015///gamma-tubulin binding GO:0008150///biological_process+++GO:0060271///cilium assembly+++GO:0070507///regulation of microtubule cytoskeleton organization 68126 68126 'Fahd2a' mRNA 635 556 610 32.36 27.83 32.49 23.64 22.55 22 30.89333333 22.73 536 500 488 600.3333333 508 0.044294031 -0.254902686 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding 68133 68133 'Gcsh' mRNA 583 703 608 28.5 33.93 31.54 35.22 33.36 35.98 31.32333333 34.85333333 827 764 817 631.3333333 802.6666667 0.002215277 0.335254463 "00260///Glycine, serine and threonine metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005960///glycine cleavage complex GO:0004047///aminomethyltransferase activity+++GO:0019899///enzyme binding GO:0009249///protein lipoylation+++GO:0019464///glycine decarboxylation via glycine cleavage system 68134 68134 'Upf3b' mRNA 707.22 661.07 679.93 15 13.73 15.54 10.68 12.32 11.71 14.75666667 11.57 556 632.14 602.05 682.74 596.73 0.097209656 -0.204874588 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034451///centriolar satellite+++GO:0035145///exon-exon junction complex GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006986///response to unfolded protein+++GO:0045727///positive regulation of translation" 68135 68135 'Eif3h' mRNA 2025 2113 1996 100.63 103.68 105.26 113.16 107.24 111.1 103.19 110.5 2615 2415 2482 2044.666667 2504 3.72E-05 0.280212047 05162///Measles "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0042788///polysomal ribosome+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003743///translation initiation factor activity+++GO:0008237///metallopeptidase activity+++GO:0070122///isopeptidase activity+++GO:0101005///ubiquitinyl hydrolase activity GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006508///proteolysis+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process 68137 68137 'Kdelr1' mRNA 592 604 465 22.88 23.03 19.07 30.11 25.28 30.4 21.66 28.59666667 895 733 874 553.6666667 834 5.51E-07 0.58251369 05110///Vibrio cholerae infection GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0005046///KDEL sequence binding+++GO:0046923///ER retention sequence binding "GO:0002369///T cell cytokine production+++GO:0006621///protein retention in ER lumen+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030217///T cell differentiation+++GO:0070231///T cell apoptotic process" 68140 68140 'Tigd2' mRNA 486 479 508 8.88 8.61 9.84 9.27 7.83 8.7 9.11 8.6 584 482 531 491 532.3333333 0.504134736 0.101547948 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding GO:0008150///biological_process 68142 68142 'Ino80' mRNA 503.04 461.66 438.57 2.39 2.07 2.46 2.12 2.25 2.2 2.306666667 2.19 515.24 487.08 497.2 467.7566667 499.84 0.565603422 0.0855288 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016604///nuclear body+++GO:0031011///Ino80 complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042393///histone binding+++GO:0043014///alpha-tubulin binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0000070///mitotic sister chromatid segregation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006338///chromatin remodeling+++GO:0006351///transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0030307///positive regulation of cell growth+++GO:0032508///DNA duplex unwinding+++GO:0034644///cellular response to UV+++GO:0042766///nucleosome mobilization+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043618///regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0070914///UV-damage excision repair+++GO:0071479///cellular response to ionizing radiation+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 68145 68145 'Etaa1' mRNA 166 177 71 2.13 2.24 0.97 0.69 0.73 0.96 1.78 0.793333333 62 64 83 138 69.66666667 0.002665764 -0.979938182 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0043596///nuclear replication fork GO:0043539///protein serine/threonine kinase activator activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000001///regulation of DNA damage checkpoint 68146 68146 'Arl13b' mRNA 407 378 380 6.18 5.68 6.07 4.43 4.17 5.27 5.976666667 4.623333333 333 308 386 388.3333333 342.3333333 0.230755032 -0.193935443 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0001947///heart looping+++GO:0007224///smoothened signaling pathway+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0009953///dorsal/ventral pattern formation+++GO:0010226///response to lithium ion+++GO:0021532///neural tube patterning+++GO:0021830///interneuron migration from the subpallium to the cortex+++GO:0021943///formation of radial glial scaffolds+++GO:0060271///cilium assembly+++GO:0070986///left/right axis specification+++GO:0097500///receptor localization to non-motile cilium+++GO:1905515///non-motile cilium assembly 68147 68147 'Gar1' mRNA 212 198 153 10.12 9.33 7.76 5.75 10.54 9.55 9.07 8.613333333 138 247 222 187.6666667 202.3333333 0.735918097 0.1073879 03008///Ribosome biogenesis in eukaryotes "GO:0000781///chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0001651///dense fibrillar component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0015030///Cajal body+++GO:0031429///box H/ACA snoRNP complex+++GO:0090661///box H/ACA telomerase RNP complex" GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030515///snoRNA binding+++GO:0034513///box H/ACA snoRNA binding+++GO:0070034///telomerase RNA binding GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0006364///rRNA processing+++GO:0007004///telomere maintenance via telomerase+++GO:0042254///ribosome biogenesis 68149 68149 'Otub2' mRNA 383 423 442 7.47 8.09 9.17 5.18 4 4.83 8.243333333 4.67 304 229 275 416 269.3333333 3.41E-05 -0.643589813 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019784///NEDD8-specific protease activity+++GO:0043130///ubiquitin binding GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1901315///negative regulation of histone H2A K63-linked ubiquitination+++GO:2000780///negative regulation of double-strand break repair 68151 68151 'Wls' mRNA 5680 6165 6102 94.56 103.43 107.95 148.37 150.96 144.3 101.98 147.8766667 10208 10099 9564 5982.333333 9957 1.79E-30 0.721689699 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031301///integral component of organelle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032590///dendrite membrane+++GO:0032839///dendrite cytoplasm GO:0005515///protein binding+++GO:0017147///Wnt-protein binding+++GO:0031852///mu-type opioid receptor binding+++GO:0042802///identical protein binding GO:0001707///mesoderm formation+++GO:0006886///intracellular protein transport+++GO:0007275///multicellular organism development+++GO:0009948///anterior/posterior axis specification+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030901///midbrain development+++GO:0030902///hindbrain development+++GO:0031017///exocrine pancreas development+++GO:0061355///Wnt protein secretion+++GO:0061357///positive regulation of Wnt protein secretion+++GO:0090263///positive regulation of canonical Wnt signaling pathway 68152 68152 'Fam133b' mRNA 276 243 340 6.72 5.83 8.79 5.36 6.31 6.02 7.113333333 5.896666667 253 291 275 286.3333333 273 0.728310548 -0.086728554 GO:0005575///cellular_component GO:0008150///biological_process 68153 68153 'Gtf2e2' mRNA 671 672 685 24.3 24.46 26.65 23.17 25.93 23.37 25.13666667 24.15666667 713 783 709 676 735 0.397642344 0.108659913 03022///Basal transcription factors+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005673///transcription factor TFIIE complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter 68159 68159 'Stx19' mRNA 21 19 8 1.09 0.97 0.44 0.9 0.42 0.42 0.833333333 0.58 20 9 9 16 12.66666667 0.714857462 -0.341005251 04130///SNARE interactions in vesicular transport GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0048787///presynaptic active zone membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0016192///vesicle-mediated transport+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0048278///vesicle docking 68165 68165 'Fdx2' mRNA 458 451 424 38.55 37.62 37.87 51.55 49.91 52.47 38.01333333 51.31 701 661 689 444.3333333 683.6666667 1.66E-08 0.610376412 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0009055///electron transfer activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0008150///biological_process+++GO:0022900///electron transport chain 68166 68166 'Spire1' mRNA 1169 1185 1157 11.51 11.69 12.38 6.8 7.18 7.02 11.86 7 779 803 771 1170.333333 784.3333333 3.88E-11 -0.589160298 04320///Dorso-ventral axis formation GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032154///cleavage furrow+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0003779///actin binding GO:0001662///behavioral fear response+++GO:0007015///actin filament organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0036089///cleavage furrow formation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0045010///actin nucleation+++GO:0046907///intracellular transport+++GO:0048193///Golgi vesicle transport+++GO:0051295///establishment of meiotic spindle localization+++GO:0051639///actin filament network formation+++GO:0060996///dendritic spine development+++GO:0070649///formin-nucleated actin cable assembly+++GO:0090141///positive regulation of mitochondrial fission+++GO:2000781///positive regulation of double-strand break repair 68169 68169 'Ndnf' mRNA 193 255 225 1.5 1.84 2.15 1.72 1.78 1.73 1.83 1.743333333 246 242 232 224.3333333 240 0.71652474 0.085585193 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding GO:0001525///angiogenesis+++GO:0001764///neuron migration+++GO:0002931///response to ischemia+++GO:0007263///nitric oxide mediated signal transduction+++GO:0007399///nervous system development+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0010976///positive regulation of neuron projection development+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030198///extracellular matrix organization+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0061042///vascular wound healing+++GO:0071456///cellular response to hypoxia+++GO:2000352///negative regulation of endothelial cell apoptotic process 68170 68170 'Iftap' mRNA 1070 1083 985 25.92 25.83 25.31 21.02 22.16 21.21 25.68666667 21.46333333 998 1028 975 1046 1000.333333 0.484096476 -0.07459801 GO:0005829///cytosol+++GO:0097731///9+0 non-motile cilium GO:0120160///intraciliary transport particle A binding GO:0007283///spermatogenesis+++GO:0007340///acrosome reaction+++GO:0009566///fertilization 68172 68172 'Rpl39l' mRNA 4 4 2 0.34 0.33 0.18 0.15 0.39 0.23 0.283333333 0.256666667 2 5 3 3.333333333 3.333333333 0.998591786 0.006029436 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation 68176 68176 'Inka1' mRNA 145 163 136 8.61 9.56 8.56 15.47 15.66 16.92 8.91 16.01666667 299 295 316 148 303.3333333 7.38E-10 1.025833356 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity GO:0021915///neural tube development+++GO:0043086///negative regulation of catalytic activity 68177 68177 'Ebpl' mRNA 454 419 404 12.39 11.27 11.7 12.01 13.04 13.35 11.78666667 12.8 506 536 544 425.6666667 528.6666667 0.017537172 0.302324338 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0047750///cholestenol delta-isomerase activity GO:0008150///biological_process+++GO:0016125///sterol metabolic process 68178 68178 'Cgnl1' mRNA 1205 1191 1097 8.98 8.73 8.69 7.86 7.57 7.99 8.8 7.806666667 1209 1133 1192 1164.333333 1178 0.960236617 0.005891042 04530///Tight junction GO:0005923///bicellular tight junction+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043296///apical junction complex GO:0003674///molecular_function GO:0007015///actin filament organization+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0051497///negative regulation of stress fiber assembly 68183 68183 'Bcas2' mRNA 1619.49 1498.48 1472.45 64.84 59.18 62.61 57.92 57.03 57.01 62.21 57.32 1659.95 1593.59 1580.76 1530.14 1611.433333 0.509847871 0.062708407 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005662///DNA replication factor A complex+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 68184 68184 'Denr' mRNA 842.38 930.98 938.21 35.3 35.96 39.89 50.84 53.72 49.95 37.05 51.50333333 1406.14 1417 1324.22 903.8566667 1382.453333 1.09E-10 0.600401689 GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity GO:0001731///formation of translation preinitiation complex+++GO:0002188///translation reinitiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly+++GO:0075522///IRES-dependent viral translational initiation 68185 68185 'Coa4' mRNA 213 218 224 14.37 15.64 16.35 18.55 18.56 16.8 15.45333333 17.97 278 275 248 218.3333333 267 0.121006833 0.277103365 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 68187 68187 'Fam135a' mRNA 541 660 631 4.93 5.87 6.11 5.09 4.33 5.2 5.636666667 4.873333333 643 532 642 610.6666667 605.6666667 0.872094274 -0.026187987 GO:0005575///cellular_component GO:0044255///cellular lipid metabolic process 68188 68188 'Sympk' mRNA 1055 1047 802 13.75 13.41 11.08 11.62 10.98 11.87 12.74666667 11.49 1027 947 1015 968 996.3333333 0.808478082 0.034498811 03015///mRNA surveillance pathway+++04530///Tight junction GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0097165///nuclear stress granule GO:0003674///molecular_function GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0007155///cell adhesion+++GO:0032091///negative regulation of protein binding+++GO:0035307///positive regulation of protein dephosphorylation 68192 68192 'Leprotl1' mRNA 816 842 665 17.54 17.82 15.16 22.01 22.98 20.98 16.84 21.99 1178 1201 1087 774.3333333 1155.333333 4.58E-09 0.569707211 GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0060400///negative regulation of growth hormone receptor signaling pathway+++GO:2000009///negative regulation of protein localization to cell surface 68193 68193 'Rpl24' mRNA 2820 2521 2721 300.44 266.84 307.68 340.6 373.79 371.09 291.6533333 361.8266667 3653 3900 3839 2687.333333 3797.333333 2.33E-10 0.486141719 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0046872///metal ion binding" "GO:0000027///ribosomal large subunit assembly+++GO:0002181///cytoplasmic translation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006412///translation+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008150///biological_process+++GO:0010458///exit from mitosis+++GO:0021554///optic nerve development+++GO:0031290///retinal ganglion cell axon guidance+++GO:0060041///retina development in camera-type eye+++GO:1902626///assembly of large subunit precursor of preribosome" 68194 68194 'Ndufb4' mRNA 1606.22 1570.83 1638.42 320.88 314.9 347.64 262.25 304.06 282.13 327.8066667 282.8133333 1488.97 1672.72 1539.03 1605.156667 1566.906667 0.691544474 -0.047164633 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function+++GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0006979///response to oxidative stress+++GO:0032981///mitochondrial respiratory chain complex I assembly 68195 68195 'Rnaset2b' mRNA 224.64 457.09 437.48 14.13 28.44 29.2 33.59 55.61 45.12 23.92333333 44.77333333 612.06 987.81 794.71 373.07 798.1933333 0.010736601 1.085267548 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043202///lysosomal lumen GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0033897///ribonuclease T2 activity "GO:0002376///immune system process+++GO:0006401///RNA catabolic process+++GO:0045087///innate immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 68196 68196 'Hsbp1' mRNA 4340 4355 4308 230.16 228.14 242.4 261.17 285.79 279.35 233.5666667 275.4366667 5651 6030 5844 4334.333333 5841.666667 4.20E-11 0.418911538 04212///Longevity regulating pathway - worm GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:1904115///axon cytoplasm GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding "GO:0006936///muscle contraction+++GO:0019896///axonal transport of mitochondrion+++GO:0035987///endodermal cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070370///cellular heat acclimation" 68197 68197 'Ndufc2' mRNA 1959 1944 1948 207.85 204.91 219.36 230.91 250.34 232.17 210.7066667 237.8066667 2487 2623 2412 1950.333333 2507.333333 3.18E-06 0.350401629 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0008137///NADH dehydrogenase (ubiquinone) activity "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0050727///regulation of inflammatory response+++GO:0060547///negative regulation of necrotic cell death+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:2001171///positive regulation of ATP biosynthetic process" 68198 68198 'Ndufb2' mRNA 1359 1333 1639 108.22 105.11 138.47 92.4 128.01 111.38 117.2666667 110.5966667 1329 1793 1547 1443.666667 1556.333333 0.563504144 0.093450912 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 68201 68201 'Ccdc34' mRNA 421 353 327 11.32 9.37 9.15 9.11 8.32 8.88 9.946666667 8.77 389 345 368 367 367.3333333 0.965568268 -0.008953894 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68202 68202 'Ndufa5' mRNA 1215 1305 1517 175.05 188.1 232.69 161.34 196.39 168.53 198.6133333 175.42 1276 1511 1279 1345.666667 1355.333333 0.978276716 -0.005335079 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0045271///respiratory chain complex I+++GO:0070469///respiratory chain GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0022904///respiratory electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly 68203 68203 'Diras2' mRNA 124 67 116 1.53 0.81 1.52 0.53 0.4 0.35 1.286666667 0.426666667 49 36 32 102.3333333 39 5.03E-05 -1.413522112 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding GO:0007165///signal transduction+++GO:0008150///biological_process 68205 68205 'Urm1' mRNA 289 292 145 7.62 7.59 4.06 6.67 6.27 6.54 6.423333333 6.493333333 291 267 276 242 278 0.427203567 0.201037904 04122///Sulfur relay system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0031386///protein tag+++GO:0097163///sulfur carrier activity GO:0002098///tRNA wobble uridine modification+++GO:0008033///tRNA processing+++GO:0032447///protein urmylation+++GO:0034227///tRNA thio-modification 68209 68209 'Rnaseh2c' mRNA 308 290 303 35.23 32.98 36.78 43.87 44.39 39.68 34.99666667 42.64666667 438 431 382 300.3333333 417 0.001245501 0.460475708 03030///DNA replication GO:0005634///nucleus+++GO:0032299///ribonuclease H2 complex GO:0006401///RNA catabolic process 68212 68212 'Tmbim4' mRNA 2034 2168 2118 170.93 180.57 188.88 187.13 186.81 184.31 180.1266667 186.0833333 2549 2478 2424 2106.666667 2483.666667 0.002263806 0.224767283 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0050848///regulation of calcium-mediated signaling 68214 68214 'Gsto2' mRNA 58 72 51 2.68 3.25 2.49 0.88 1.02 0.83 2.806666667 0.91 22 25 20 60.33333333 22.33333333 3.00E-04 -1.439783296 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm GO:0004364///glutathione transferase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0045174///glutathione dehydrogenase (ascorbate) activity+++GO:0050610///methylarsonate reductase activity GO:0006749///glutathione metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019852///L-ascorbic acid metabolic process+++GO:0071243///cellular response to arsenic-containing substance+++GO:0098869///cellular oxidant detoxification 68215 68215 'Fam98b' mRNA 205 210 183 6.34 6.41 6 4.83 5.83 5.34 6.25 5.333333333 179 211 192 199.3333333 194 0.862117301 -0.047496602 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072669///tRNA-splicing ligase complex GO:0008276///protein methyltransferase activity+++GO:0042802///identical protein binding GO:0006479///protein methylation+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression 68219 68219 'Nudt21' mRNA 636 600 630 35.72 33.3 37.54 57.68 52.83 55.51 35.52 55.34 1178 1052 1096 622 1108.666667 1.28E-17 0.820069266 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005849///mRNA cleavage factor complex+++GO:0016604///nuclear body+++GO:0034451///centriolar satellite+++GO:0042382///paraspeckles GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding GO:0006378///mRNA polyadenylation+++GO:0006379///mRNA cleavage+++GO:0006397///mRNA processing+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031439///positive regulation of mRNA cleavage+++GO:0051262///protein tetramerization+++GO:0051290///protein heterotetramerization+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:0110104///mRNA alternative polyadenylation+++GO:1900365///positive regulation of mRNA polyadenylation+++GO:1990120///messenger ribonucleoprotein complex assembly+++GO:2000738///positive regulation of stem cell differentiation+++GO:2000975///positive regulation of pro-B cell differentiation 68222 68222 'Fam166a' mRNA 21 17 19 1 0.93 0.87 0.42 0.59 0.2 0.933333333 0.403333333 13 14 5 19 10.66666667 0.25731504 -0.846580525 GO:0036064///ciliary basal body GO:0003674///molecular_function GO:0008150///biological_process 68226 68226 'Efcab2' mRNA 306 335 400 4.53 4.88 6.28 1.95 1.87 2.16 5.23 1.993333333 152 142 163 347 152.3333333 2.34E-11 -1.205563103 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0005509///calcium ion binding GO:0008150///biological_process 68229 68229 'Spindoc' mRNA 294.03 293.12 272 3.19 2.86 3.01 3.17 3.35 2.57 3.02 3.03 255.82 254.69 222 286.3833333 244.17 0.155991217 -0.243768443 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0045892///negative regulation of transcription, DNA-templated" 68231 68231 'H2al2a' mRNA 0 0 1 0 0 0.16 0 0 0 0.053333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0035327///transcriptionally active chromatin+++GO:0044815///DNA packaging complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0046982///protein heterodimerization activity "GO:0006323///DNA packaging+++GO:0006334///nucleosome assembly+++GO:0006342///chromatin silencing+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0031507///heterochromatin assembly+++GO:0035093///spermatogenesis, exchange of chromosomal proteins" 68233 68233 'Fam229a' mRNA 19 17 13 2.7 2.41 1.96 1.87 1.16 1.3 2.356666667 1.443333333 15 9 10 16.33333333 11.33333333 0.500382774 -0.537552802 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68235 68235 'Mturn' mRNA 651 701 678 7 7.78 7.8 5.64 5.34 4.99 7.526666667 5.323333333 624 567 554 676.6666667 581.6666667 0.046315829 -0.231357291 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0046330///positive regulation of JNK cascade+++GO:0048666///neuron development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 68236 68236 'Gtsf1l' mRNA 2 0 0 0.15 0 0 0.07 0.07 0.07 0.05 0.07 1 1 1 0.666666667 1 0.863357859 0.593736086 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 68240 68240 'Rpa3' mRNA 171 169 186 19.91 19.57 22.99 29.88 31.99 31.42 20.82333333 31.09666667 293 305 297 175.3333333 298.3333333 7.13E-06 0.75327266 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0035861///site of double-strand break GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006298///mismatch repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0042127///regulation of cell proliferation 68241 68241 'Mcrip2' mRNA 179 197 177 14.69 15.93 15.41 18.05 17.42 17.5 15.34333333 17.65666667 254 236 235 184.3333333 241.6666667 0.034401721 0.379324928 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule GO:0005515///protein binding GO:0008150///biological_process 68243 68243 'A930018P22Rik' mRNA 4 2 0 0.33 0.16 0 0.07 0.07 0.07 0.163333333 0.07 1 1 1 2 1 0.722185492 -0.982668069 GO:0003674///molecular_function GO:0008150///biological_process 68250 68250 'Ciao2a' mRNA 984 1005 966 47.85 48.1 49.82 74.5 74.4 70.23 48.59 73.04333333 1759 1713 1607 985 1693 3.52E-22 0.769426846 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097361///CIA complex GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007059///chromosome segregation+++GO:0016226///iron-sulfur cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer 68251 68251 'Babam1' mRNA 1503.81 1640 1542 58.56 62.28 63.29 61.65 65.34 63.37 61.37666667 63.45333333 1816.99 1883.99 1806 1561.936667 1835.66 0.006324191 0.221286129 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0070531///BRCA1-A complex+++GO:0070552///BRISC complex GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010212///response to ionizing radiation+++GO:0045739///positive regulation of DNA repair+++GO:0051301///cell division+++GO:0070536///protein K63-linked deubiquitination+++GO:0071425///hematopoietic stem cell proliferation+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint 68255 68255 'Tmem86b' mRNA 15 18 24 0.76 0.86 1.32 1.13 1.4 1.85 0.98 1.46 27 32 41 19 33.33333333 0.144399979 0.79384033 00565///Ether lipid metabolism GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0047408///alkenylglycerophosphocholine hydrolase activity+++GO:0047409///alkenylglycerophosphoethanolamine hydrolase activity GO:0046485///ether lipid metabolic process 68259 68259 'Ift80' mRNA 1112 1131 1056 14.65 14.66 14.8 7.28 6.68 7.18 14.70333333 7.046666667 634 568 607 1099.666667 603 6.04E-22 -0.878646864 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097731///9+0 non-motile cilium GO:0003674///molecular_function GO:0001501///skeletal system development+++GO:0001649///osteoblast differentiation+++GO:0001958///endochondral ossification+++GO:0002062///chondrocyte differentiation+++GO:0003417///growth plate cartilage development+++GO:0003418///growth plate cartilage chondrocyte differentiation+++GO:0007224///smoothened signaling pathway+++GO:0033687///osteoblast proliferation+++GO:0035630///bone mineralization involved in bone maturation+++GO:0042073///intraciliary transport+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060173///limb development+++GO:0060271///cilium assembly+++GO:0060349///bone morphogenesis+++GO:0061975///articular cartilage development+++GO:0097500///receptor localization to non-motile cilium+++GO:1905515///non-motile cilium assembly+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway 68260 68260 'Trmt12' mRNA 342 342 355 4.46 4.39 4.91 3.87 4.9 4.57 4.586666667 4.446666667 342 423 391 346.3333333 385.3333333 0.416460876 0.142632978 GO:0005737///cytoplasm GO:0008175///tRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0102522///tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation 68262 68262 'Agpat4' mRNA 1018 1086 1031 30.23 31.9 32.6 26.89 24.62 24.65 31.57666667 25.38666667 1034 926 918 1045 959.3333333 0.181105983 -0.136175527 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04072///Phospholipase D signaling pathway GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042171///lysophosphatidic acid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process 68263 68263 'Pdhb' mRNA 2513 2566 2383 100.03 100.83 100.67 90.35 94.37 91.31 100.51 92.01 2605 2654 2547 2487.333333 2602 0.500483686 0.054241345 00010///Glycolysis / Gluconeogenesis+++00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway+++05230///Central carbon metabolism in cancer+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005967///mitochondrial pyruvate dehydrogenase complex+++GO:0045254///pyruvate dehydrogenase complex GO:0003824///catalytic activity+++GO:0004739///pyruvate dehydrogenase (acetyl-transferring) activity+++GO:0016491///oxidoreductase activity+++GO:0034604///pyruvate dehydrogenase (NAD+) activity GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006099///tricarboxylic acid cycle+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate 68265 68265 'Iqcf3' mRNA 0 0 3 0 0 0.18 0 0.12 0.05 0.06 0.056666667 0 1 1 1 0.666666667 0.863090843 -0.649449774 GO:0001669///acrosomal vesicle GO:0005516///calmodulin binding GO:2000344///positive regulation of acrosome reaction 68267 68267 'Slc25a22' mRNA 1062 1047 987 23.09 22.31 22.64 20.03 19.78 19.47 22.68 19.76 1067 1032 1003 1032 1034 0.942516612 -0.008497772 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0015810///aspartate transmembrane transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0055085///transmembrane transport+++GO:0070778///L-aspartate transmembrane transport 68268 68268 'Zdhhc21' mRNA 854.47 956.05 759.66 3.94 4.34 3.72 3.83 3.11 3.3 4 3.413333333 888.64 694.94 747.12 856.7266667 776.9 0.223879108 -0.151845169 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0001942///hair follicle development+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0048733///sebaceous gland development+++GO:0071875///adrenergic receptor signaling pathway+++GO:1903140///regulation of establishment of endothelial barrier+++GO:1904997///regulation of leukocyte adhesion to arterial endothelial cell 68270 68270 'Dnaaf1' mRNA 230.28 236.5 262.8 4.5 4.55 5.45 0.53 0.41 0.55 4.833333333 0.496666667 31.02 23.37 31.54 243.1933333 28.64333333 8.87E-35 -3.114797886 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016607///nuclear speck+++GO:0042995///cell projection GO:0070840///dynein complex binding GO:0001947///heart looping+++GO:0003341///cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0030324///lung development+++GO:0035469///determination of pancreatic left/right asymmetry+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:0060972///left/right pattern formation+++GO:0070286///axonemal dynein complex assembly+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0071910///determination of liver left/right asymmetry 68272 68272 'Rbm28' mRNA 741.67 686.97 656.9 9.57 8.71 8.98 8.64 7.81 8.64 9.086666667 8.363333333 771.77 680.85 747.44 695.18 733.3533333 0.618281259 0.065841291 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing 68273 68273 'Pomgnt1' mRNA 539 554 516 10.99 11.14 11.14 11.52 12.5 12.5 11.09 12.17333333 651 690 684 536.3333333 675 0.004015125 0.321311302 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0047223///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0016266///O-glycan processing 68275 68275 'Rpa1' mRNA 1287.16 1333.31 1169.39 23.18 23.63 22.34 22.24 23.99 22.38 23.05 22.87 1421.17 1497.08 1384.05 1263.286667 1434.1 0.046766961 0.173802409 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0000793///condensed chromosome+++GO:0000794///condensed nuclear chromosome+++GO:0000800///lateral element+++GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0016605///PML body+++GO:0090734///site of DNA damage GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0046872///metal ion binding+++GO:0098505///G-rich strand telomeric DNA binding GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0001701///in utero embryonic development+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006298///mismatch repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007004///telomere maintenance via telomerase+++GO:0008284///positive regulation of cell proliferation+++GO:0030097///hemopoiesis+++GO:0034502///protein localization to chromosome+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051276///chromosome organization+++GO:0051321///meiotic cell cycle 68276 68276 'Toe1' mRNA 517.59 546.69 450.76 14.62 15.21 13.51 12.46 13.68 12.16 14.44666667 12.76666667 507.88 545.34 479.09 505.0133333 510.77 0.9594962 0.008842283 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0016607///nuclear speck GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0017069///snRNA binding+++GO:0046872///metal ion binding "GO:0034472///snRNA 3'-end processing+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 68277 68277 '2310057M21Rik' mRNA 337 303 331 5.49 4.86 5.72 3.48 3.96 3.8 5.356666667 3.746666667 246 273 260 323.6666667 259.6666667 0.044372853 -0.33039301 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0008150///biological_process 68278 68278 'Ddx39a' mRNA 601 651 594 20.87 22.27 21.86 46.77 47.1 45.22 21.66666667 46.36333333 1539 1514 1441 615.3333333 1498 1.10E-49 1.272470176 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing" 68279 68279 'Mcoln2' mRNA 36 37 21 0.79 0.81 0.47 2.28 2.72 1.98 0.69 2.326666667 118 138 99 31.33333333 118.3333333 1.54E-09 1.914281574 04020///Calcium signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0042802///identical protein binding+++GO:0072345///NAADP-sensitive calcium-release channel activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0015031///protein transport+++GO:0032722///positive regulation of chemokine production+++GO:0034220///ion transmembrane transport+++GO:0045087///innate immune response+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0070588///calcium ion transmembrane transport+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071642///positive regulation of macrophage inflammatory protein 1 alpha production+++GO:0071651///positive regulation of chemokine (C-C motif) ligand 5 production+++GO:0098655///cation transmembrane transport+++GO:1905517///macrophage migration+++GO:1990266///neutrophil migration+++GO:2000341///regulation of chemokine (C-X-C motif) ligand 2 production+++GO:2000343///positive regulation of chemokine (C-X-C motif) ligand 2 production 68281 68281 '4930430F08Rik' mRNA 416.28 485.57 473.85 8.12 9.43 9.69 4.31 3.83 4.04 9.08 4.06 268.16 223.76 234.32 458.5666667 242.08 1.03E-10 -0.936888223 GO:0005575///cellular_component GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 68283 68283 '9530077C05Rik' mRNA 692.51 711.91 675.44 16.24 17.57 17.19 9.89 10.88 11.95 17 10.90666667 564.71 571.09 577.86 693.2866667 571.22 0.007556462 -0.290790515 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68291 68291 'Mto1' mRNA 384 420 422 9.09 9.8 10.6 9 10.17 9.32 9.83 9.496666667 437 482 438 408.6666667 452.3333333 0.391996628 0.134110224 GO:0005739///mitochondrion GO:0050660///flavin adenine dinucleotide binding GO:0002098///tRNA wobble uridine modification+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0070899///mitochondrial tRNA wobble uridine modification 68292 68292 'Stt3b' mRNA 2035 2156 1001 24.97 26.02 13.03 12.14 15.99 16.18 21.34 14.77 1139 1465 1470 1730.666667 1358 0.404685789 -0.342266136 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0034998///oligosaccharyltransferase I complex "GO:0004576///oligosaccharyl transferase activity+++GO:0004579///dolichyl-diphosphooligosaccharide-protein glycotransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0006516///glycoprotein catabolic process+++GO:0006986///response to unfolded protein+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043686///co-translational protein modification+++GO:0043687///post-translational protein modification 68294 68294 'Mfsd10' mRNA 774 708 639 24.03 21.92 21.26 23.44 25.59 25.39 22.40333333 24.80666667 877 930 917 707 908 6.35E-04 0.352082243 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031526///brush border membrane GO:0008514///organic anion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006915///apoptotic process+++GO:0043252///sodium-independent organic anion transport+++GO:0055085///transmembrane transport 68295 68295 'Aar2' mRNA 1436 1556 1414 26.65 28.3 27.96 20.97 21.24 21.79 27.63666667 21.33333333 1302 1277 1294 1468.666667 1291 0.01682061 -0.197036584 GO:0005575///cellular_component+++GO:0005681///spliceosomal complex GO:0003674///molecular_function+++GO:0005515///protein binding GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 68298 68298 'Ncapd2' mRNA 950 965.01 961 11.29 11.28 12.06 10.02 9.53 8.98 11.54333333 9.51 968 910 844 958.67 907.3333333 0.416795003 -0.092535683 "GO:0000228///nuclear chromosome+++GO:0000779///condensed chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045120///pronucleus" GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0051301///cell division 68299 68299 'Vps53' mRNA 1132 1132 1161 22.38 22.04 24.56 17.92 16.6 16.87 22.99333333 17.13 970 889 889 1141.666667 916 3.67E-04 -0.331511469 GO:0000938///GARP complex+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:1990745///EARP complex "GO:0007041///lysosomal transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi" 68303 68303 'Fam114a1' mRNA 685 803 818 12.77 14.74 16.18 18.51 16.99 17.43 14.56333333 17.64333333 1142 1024 1041 768.6666667 1069 2.00E-05 0.460690078 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 68304 68304 'Poglut3' mRNA 307.1 295.54 134.8 4.57 4.33 2.13 2.71 3.92 4.09 3.676666667 3.573333333 209.19 296.24 305.85 245.8133333 270.4266667 0.651886837 0.14574967 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0012505///endomembrane system "GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity+++GO:0046527///glucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0008150///biological_process+++GO:0018242///protein O-linked glycosylation via serine 68307 68307 'Lrriq4' mRNA 4 2 6 0.11 0.05 0.17 0.16 0.16 0.12 0.11 0.146666667 7 7 5 4 6.333333333 0.64509722 0.635292327 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0004722///protein serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction 68310 68310 'Zmym1' mRNA 203.64 253.6 226.49 2.94 3.59 3.52 3.23 2.33 3.3 3.35 2.953333333 266.79 187.47 246.15 227.91 233.47 0.931813657 0.021414589 GO:0008270///zinc ion binding+++GO:0046983///protein dimerization activity GO:0008150///biological_process 68311 68311 'Lypd2' mRNA 14 11 14 2.44 1.92 2.59 1.23 1.11 2.39 2.316666667 1.576666667 8 8 15 13 10.33333333 0.722539084 -0.345241677 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0003674///molecular_function 68312 68312 'Gstm7' mRNA 3070 2967 2895 137.82 130.74 137.83 32.42 33.08 36.92 135.4633333 34.14 851 840 923 2977.333333 871.3333333 2.97E-127 -1.784325185 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016529///sarcoplasmic reticulum+++GO:0045171///intercellular bridge GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005102///signaling receptor binding+++GO:0005504///fatty acid binding+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding GO:0006749///glutathione metabolic process+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0043651///linoleic acid metabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0070458///cellular detoxification of nitrogen compound+++GO:0071313///cellular response to caffeine+++GO:0098869///cellular oxidant detoxification 68316 68316 'Apoo' mRNA 852 890 843 59.27 60.62 62 47.77 47.04 48.39 60.63 47.73333333 779 754 769 861.6666667 767.3333333 0.078972068 -0.1790079 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0061617///MICOS complex GO:0042407///cristae formation 68318 68318 'Aph1c' mRNA 696.23 714.38 763.98 6.8 6.96 8 9.55 9.66 9.57 7.253333333 9.593333333 1106.82 1093.99 1070.06 724.8633333 1090.29 5.64E-09 0.575066311 04330///Notch signaling pathway+++05010///Alzheimer disease GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0045202///synapse+++GO:0070765///gamma-secretase complex "GO:0030674///protein binding, bridging+++GO:0061133///endopeptidase activator activity" "GO:0001656///metanephros development+++GO:0001963///synaptic transmission, dopaminergic+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007219///Notch signaling pathway+++GO:0007220///Notch receptor processing+++GO:0007614///short-term memory+++GO:0007626///locomotory behavior+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016485///protein processing+++GO:0034205///amyloid-beta formation+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0060134///prepulse inhibition" 68323 68323 'Nudt22' mRNA 423 379 370 27.15 24.12 25.2 32.77 30.14 31.75 25.49 31.55333333 585 525 548 390.6666667 552.6666667 6.61E-05 0.488680842 GO:0005654///nucleoplasm GO:0008768///UDP-sugar diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0052751///GDP-mannose hydrolase activity GO:0008150///biological_process 68327 68327 'Tsr3' mRNA 779.82 691.64 724.45 41.9 37 41.61 33.25 33.74 35.11 40.17 34.03333333 712.86 704.33 716.84 731.97 711.3433333 0.703304273 -0.053770693 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0016740///transferase activity+++GO:1904047///S-adenosyl-L-methionine binding GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0006364///rRNA processing+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis 68328 68328 'Rab13' mRNA 857 847 821 33.11 32.36 33.9 33.13 30.83 31.27 33.12333333 31.74333333 986 896 900 841.6666667 927.3333333 0.223161236 0.127427643 04530///Tight junction GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032593///insulin-responsive compartment+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0034236///protein kinase A catalytic subunit binding GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0010737///protein kinase A signaling+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0017157///regulation of exocytosis+++GO:0030866///cortical actin cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0032456///endocytic recycling+++GO:0032869///cellular response to insulin stimulus+++GO:0035767///endothelial cell chemotaxis+++GO:0044795///trans-Golgi network to recycling endosome transport+++GO:0048210///Golgi vesicle fusion to target membrane+++GO:0070830///bicellular tight junction assembly+++GO:0072659///protein localization to plasma membrane+++GO:0097368///establishment of Sertoli cell barrier+++GO:1902463///protein localization to cell leading edge 68332 68332 'Sdhaf1' mRNA 694 749 691 46.27 49.4 48.89 43.8 48.35 48.58 48.18666667 46.91 753 810 807 711.3333333 790 0.222236508 0.140852749 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003674///molecular_function GO:0034553///mitochondrial respiratory chain complex II assembly 68337 68337 'Crip2' mRNA 10023 10526 10077 453.34 471.32 482.11 427.41 449.94 424.14 468.9233333 433.83 10826 11099 10401 10208.66667 10775.33333 0.322867023 0.066131666 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005938///cell cortex+++GO:0030175///filopodium+++GO:0030426///growth cone GO:0001849///complement component C1q binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0030169///low-density lipoprotein particle binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding "GO:0006953///acute-phase response+++GO:0006958///complement activation, classical pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0010888///negative regulation of lipid storage+++GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0030097///hemopoiesis+++GO:0032677///regulation of interleukin-8 production+++GO:0032929///negative regulation of superoxide anion generation+++GO:0032930///positive regulation of superoxide anion generation+++GO:0032945///negative regulation of mononuclear cell proliferation+++GO:0042060///wound healing+++GO:0042310///vasoconstriction+++GO:0044793///negative regulation by host of viral process+++GO:0045087///innate immune response+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0051258///protein polymerization+++GO:0071277///cellular response to calcium ion+++GO:1900006///positive regulation of dendrite development" 68339 68339 'Ccdc88c' mRNA 545 517 461 4.61 4.02 3.79 1.45 1.34 1.27 4.14 1.353333333 205 195 159 507.6666667 186.3333333 6.97E-24 -1.456200014 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030054///cell junction GO:0001965///G-protein alpha-subunit binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0030165///PDZ domain binding+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0051959///dynein light intermediate chain binding GO:0001932///regulation of protein phosphorylation+++GO:0003383///apical constriction+++GO:0007264///small GTPase mediated signal transduction+++GO:0016055///Wnt signaling pathway+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0031648///protein destabilization+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0090090///negative regulation of canonical Wnt signaling pathway 68342 68342 'Ndufb10' mRNA 2674 2686 2754 286.07 285.51 312.71 252.42 280.46 260.05 294.7633333 264.31 2696 2914 2679 2704.666667 2763 0.863090843 0.018246989 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0008137///NADH dehydrogenase (ubiquinone) activity GO:0022900///electron transport chain+++GO:0032981///mitochondrial respiratory chain complex I assembly 68344 68344 'Tmem174' mRNA 0 0 1 0 0 0.03 0 0.04 0 0.01 0.013333333 0 2 0 0.333333333 0.666666667 0.863090843 0.906589207 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68346 68346 'Sirt5' mRNA 757.28 782.73 725.37 25.1 25.23 25.3 10.38 10.61 11.13 25.21 10.70666667 361.38 352.63 373.45 755.1266667 362.4866667 5.42E-23 -1.070935644 00760///Nicotinate and nicotinamide metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0036054///protein-malonyllysine demalonylase activity+++GO:0036055///protein-succinyllysine desuccinylase activity+++GO:0046872///metal ion binding+++GO:0061697///protein-glutaryllysine deglutarylase activity+++GO:0070403///NAD+ binding GO:0002931///response to ischemia+++GO:0006476///protein deacetylation+++GO:0010566///regulation of ketone biosynthetic process+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0036046///protein demalonylation+++GO:0036047///peptidyl-lysine demalonylation+++GO:0036048///protein desuccinylation+++GO:0036049///peptidyl-lysine desuccinylation+++GO:0061698///protein deglutarylation+++GO:0061699///peptidyl-lysine deglutarylation+++GO:1904229///regulation of succinate dehydrogenase activity+++GO:2000378///negative regulation of reactive oxygen species metabolic process 68347 68347 'Mettl26' mRNA 1542 1539 1433 128.95 127.55 127.17 101.25 104.27 94.65 127.89 100.0566667 1386 1390 1251 1504.666667 1342.333333 0.041475836 -0.17564913 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68349 68349 'Ndufs3' mRNA 2346 2367 2296 160.17 159.89 166.33 150.05 147.2 144.76 162.13 147.3366667 2519 2408 2348 2336.333333 2425 0.635429417 0.041452811 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031966///mitochondrial membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain "GO:0003954///NADH dehydrogenase activity+++GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0030308///negative regulation of cell growth+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0072593///reactive oxygen species metabolic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 68350 68350 'Mul1' mRNA 786 843.86 705 11.27 11.8 10.71 9.05 8.17 8.14 11.26 8.453333333 733 640 635 778.2866667 669.3333333 0.03915749 -0.227329451 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0043025///neuronal cell body GO:0002039///p53 binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0000266///mitochondrial fission+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006996///organelle organization+++GO:0007257///activation of JUN kinase activity+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0030308///negative regulation of cell growth+++GO:0031647///regulation of protein stability+++GO:0031648///protein destabilization+++GO:0033235///positive regulation of protein sumoylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045824///negative regulation of innate immune response+++GO:0050689///negative regulation of defense response to virus by host+++GO:0050821///protein stabilization+++GO:0051646///mitochondrion localization+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0071360///cellular response to exogenous dsRNA+++GO:0071650///negative regulation of chemokine (C-C motif) ligand 5 production+++GO:0090141///positive regulation of mitochondrial fission+++GO:1901028///regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1903861///positive regulation of dendrite extension+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 68352 68352 'Aspdh' mRNA 1 5 4 0.07 0.33 0.28 0.12 0 0.06 0.226666667 0.06 2 0 1 3.333333333 1 0.399384112 -1.764427316 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005575///cellular_component GO:0016491///oxidoreductase activity+++GO:0033735///aspartate dehydrogenase activity+++GO:0050661///NADP binding GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process 68364 68364 '0610030E20Rik' mRNA 771.13 651 658 8.44 7 7.61 8.01 7.66 7.98 7.683333333 7.883333333 844 789 814.7 693.3766667 815.9 0.047140749 0.222721225 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68365 68365 'Rab14' mRNA 5418 5461 5700 96.32 95.55 107.52 110.09 106.84 109.16 99.79666667 108.6966667 7125 6751 6841 5526.333333 6905.666667 2.12E-06 0.307164406 04152///AMPK signaling pathway GO:0000139///Golgi membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030133///transport vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042175///nuclear outer membrane-endoplasmic reticulum membrane network+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045335///phagocytic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:0097208///alveolar lamellar body+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0031489///myosin V binding GO:0006886///intracellular protein transport+++GO:0006895///Golgi to endosome transport+++GO:0007589///body fluid secretion+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0032880///regulation of protein localization+++GO:0042742///defense response to bacterium+++GO:0045176///apical protein localization+++GO:0045995///regulation of embryonic development+++GO:0090382///phagosome maturation+++GO:0090387///phagolysosome assembly involved in apoptotic cell clearance 68366 68366 'Tmem129' mRNA 1426.46 1438.63 1413.5 32.89 32.4 34.29 24.99 25.08 26.45 33.19333333 25.50666667 1251.59 1234 1288.38 1426.196667 1257.99 0.023535938 -0.192977197 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006986///response to unfolded protein+++GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol" 68371 68371 'Pbld1' mRNA 180.16 190.11 168.15 3.69 3.91 3.78 4.37 4.51 4.3 3.793333333 4.393333333 232.29 237.9 225.27 179.4733333 231.82 0.051410766 0.357287164 GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding GO:0009058///biosynthetic process+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation 68375 68375 'Ndufa8' mRNA 2395 2396 2274 205.64 203.94 207.21 222.96 235.37 213.69 205.5966667 224.0066667 2972 3055 2750 2355 2925.666667 1.83E-05 0.301890644 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0044877///protein-containing complex binding "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly" 68379 68379 'Ciz1' mRNA 1041 996 1059 20.25 19.27 22.02 15.58 15.4 15.16 20.51333333 15.38 913 887 866 1032 888.6666667 0.021988964 -0.229454802 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0030332///cyclin binding+++GO:0046872///metal ion binding GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0051457///maintenance of protein location in nucleus 68385 68385 'Tlcd1' mRNA 415 438 388 17.32 18.13 17.07 16.28 16.38 15.9 17.50666667 16.18666667 454 447 427 413.6666667 442.6666667 0.574449377 0.087373736 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007009///plasma membrane organization+++GO:0055088///lipid homeostasis+++GO:0055091///phospholipid homeostasis+++GO:0071709///membrane assembly+++GO:0097035///regulation of membrane lipid distribution 68393 68393 'Mogat1' mRNA 373 371 355 35.39 35.14 35.8 8.37 7.03 6.03 35.44333333 7.143333333 105 91 69 366.3333333 88.33333333 1.17E-29 -2.065046374 00561///Glycerolipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0004144///diacylglycerol O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006071///glycerol metabolic process+++GO:0006629///lipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0019432///triglyceride biosynthetic process 68394 68394 'Ccdc163' mRNA 361 291 316 14.37 12.21 13.41 10.88 10.53 10.62 13.33 10.67666667 306 288 285 322.6666667 293 0.399384112 -0.151962398 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68395 68395 'LOC68395' mRNA 45.15 31.77 47.67 0.73 0.51 0.82 4.06 3.18 4.02 0.686666667 3.753333333 288.73 221.21 276.78 41.53 262.24 1.03E-28 2.656648253 68396 68396 'Nat8' mRNA 597.22 601.37 579.44 31.14 31.03 32.55 53.9 54.45 49.21 31.57333333 52.52 1176.45 1192.74 1056.44 592.6766667 1141.876667 1.89E-22 0.934661709 00480///Glutathione metabolism GO:0005715///late recombination nodule+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 68401 68401 'G6pc3' mRNA 1057 964 1016 40.31 36.26 41.11 41.86 41.43 42.07 39.22666667 41.78666667 1261 1218 1226 1012.333333 1235 0.002925921 0.273792299 00010///Glycolysis / Gluconeogenesis+++00052///Galactose metabolism+++00500///Starch and sucrose metabolism+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04973///Carbohydrate digestion and absorption GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004346///glucose-6-phosphatase activity+++GO:0016787///hydrolase activity GO:0006094///gluconeogenesis+++GO:0006796///phosphate-containing compound metabolic process+++GO:0015760///glucose-6-phosphate transport+++GO:0016311///dephosphorylation+++GO:0051156///glucose 6-phosphate metabolic process 68404 68404 'Nrn1' mRNA 100 114 82 3.6 4.05 3.13 0.94 0.93 1 3.593333333 0.956666667 30 28 31 98.66666667 29.66666667 4.75E-08 -1.74039735 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0045202///synapse+++GO:0046658///anchored component of plasma membrane+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:1990138///neuron projection extension+++GO:2000300///regulation of synaptic vesicle exocytosis 68420 68420 'Ankrd13a' mRNA 358 376 367 6 6.2 6.54 8.47 8.47 8.47 6.246666667 8.47 581 568 563 367 570.6666667 1.62E-07 0.624641481 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0140036///ubiquitin-dependent protein binding GO:0002091///negative regulation of receptor internalization+++GO:1905667///negative regulation of protein localization to endosome 68421 68421 'Lmbrd1' mRNA 3934.89 4142.19 3674.73 38.94 40.67 39.01 22.19 21.24 21.92 39.54 21.78333333 2516.12 2371.97 2451.87 3917.27 2446.653333 6.36E-32 -0.689777741 04977///Vitamin digestion and absorption GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005774///vacuolar membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045334///clathrin-coated endocytic vesicle GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0031419///cobalamin binding+++GO:0032050///clathrin heavy chain binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0043495///protein membrane anchor GO:0006897///endocytosis+++GO:0007275///multicellular organism development+++GO:0007369///gastrulation+++GO:0009235///cobalamin metabolic process+++GO:0038016///insulin receptor internalization+++GO:0043408///regulation of MAPK cascade+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0061462///protein localization to lysosome+++GO:0072583///clathrin-dependent endocytosis+++GO:0072665///protein localization to vacuole 68423 68423 'Ankrd13d' mRNA 207 238 191 5.47 6.19 5.35 4.57 5.67 4.96 5.67 5.066666667 199 241 209 212 216.3333333 0.927609284 0.021920692 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0140036///ubiquitin-dependent protein binding GO:0002091///negative regulation of receptor internalization 68427 68427 'Slc39a13' mRNA 1099 1120 974 23.41 23.69 22.23 27.39 27.01 26.9 23.11 27.1 1412 1370 1358 1064.333333 1380 6.70E-06 0.364929729 05010///Alzheimer disease+++05012///Parkinson disease GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005385///zinc ion transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0010043///response to zinc ion+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0061448///connective tissue development+++GO:0071577///zinc ion transmembrane transport 68428 68428 'Steap3' mRNA 663 619 536 13.05 11.95 11.21 55.92 62.8 60.26 12.07 59.66 3279 3584 3417 606 3426.666667 3.12E-204 2.491341594 04115///p53 signaling pathway+++04216///Ferroptosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000293///ferric-chelate reductase activity+++GO:0005515///protein binding+++GO:0008823///cupric reductase activity+++GO:0016491///oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0052851///ferric-chelate reductase (NADPH) activity GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0009306///protein secretion+++GO:0015677///copper ion import+++GO:0033212///iron assimilation+++GO:0043065///positive regulation of apoptotic process+++GO:0055072///iron ion homeostasis+++GO:0098706///ferric iron import across cell outer membrane+++GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1990182///exosomal secretion 68431 68431 'Fbxl15' mRNA 264.75 219.23 217.9 11.73 9.6 10.49 11.18 11.28 10.99 10.60666667 11.15 290.16 284.66 273.77 233.96 282.8633333 0.134315602 0.264159964 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0000086///G2/M transition of mitotic cell cycle+++GO:0009953///dorsal/ventral pattern formation+++GO:0016567///protein ubiquitination+++GO:0030282///bone mineralization+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 68436 68436 'Rpl34' mRNA 659.75 698.74 756.5 101.68 110.6 124.55 224.19 247.84 244.17 112.2766667 238.7333333 1608.04 1740.02 1685.15 704.9966667 1677.736667 4.04E-37 1.238382263 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 68440 68440 'Dusp23' mRNA 124 123 92 5.22 5.11 4.11 6.59 6.53 7.08 4.813333333 6.733333333 180 174 187 113 180.3333333 0.001748577 0.66741253 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 68441 68441 'Rraga' mRNA 494 556 367 17.91 19.87 14.11 18.33 13.71 17.58 17.29666667 16.54 581 424 539 472.3333333 514.6666667 0.531670435 0.117110907 04140///Autophagy - animal+++04150///mTOR signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0071986///Ragulator complex+++GO:1990130///GATOR1 complex+++GO:1990131///Gtr1-Gtr2 GTPase complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0051219///phosphoprotein binding GO:0006915///apoptotic process+++GO:0008219///cell death+++GO:0009267///cellular response to starvation+++GO:0010506///regulation of autophagy+++GO:0010507///negative regulation of autophagy+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0034613///cellular protein localization+++GO:0042268///regulation of cytolysis+++GO:0043200///response to amino acid+++GO:0071230///cellular response to amino acid stimulus+++GO:1903432///regulation of TORC1 signaling+++GO:1904263///positive regulation of TORC1 signaling 68449 68449 'Tbc1d10b' mRNA 397 426 394 5.96 6.29 6.28 7.71 7.59 7.49 6.176666667 7.596666667 591 568 556 405.6666667 571.6666667 3.96E-05 0.483366925 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005096///GTPase activator activity "GO:0006886///intracellular protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043087///regulation of GTPase activity+++GO:0090630///activation of GTPase activity" 68453 68453 'Gpihbp1' mRNA 0 1 0 0 0.08 0 0.71 0.66 0.37 0.026666667 0.58 10 9 5 0.333333333 8 0.010020568 4.466990122 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0046658///anchored component of plasma membrane GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0035473///lipase binding+++GO:0035478///chylomicron binding+++GO:0071813///lipoprotein particle binding GO:0006869///lipid transport+++GO:0006886///intracellular protein transport+++GO:0017038///protein import+++GO:0030301///cholesterol transport+++GO:0034394///protein localization to cell surface+++GO:0042632///cholesterol homeostasis+++GO:0045056///transcytosis+++GO:0050821///protein stabilization+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0070328///triglyceride homeostasis+++GO:0071503///response to heparin+++GO:0090319///positive regulation of chylomicron remodeling+++GO:0090321///positive regulation of chylomicron remnant clearance 68458 68458 'Ppp1r14a' mRNA 59 71 63 5.94 7.43 7.83 4.38 4.33 3.69 7.066666667 4.133333333 40 37 31 64.33333333 36 0.019353121 -0.849633219 04270///Vascular smooth muscle contraction GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity GO:0035690///cellular response to drug+++GO:0042325///regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0071466///cellular response to xenobiotic stimulus 68463 68463 'Mrpl14' mRNA 1016.36 1003.95 967.37 97.57 99.04 101.28 101.47 110.12 94.13 99.29666667 101.9066667 1077.82 1127.76 960.47 995.8933333 1055.35 0.544846893 0.072222031 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 68465 68465 'Adipor2' mRNA 2700 2890 2435 36.08 37.96 34.66 36.28 32.47 38.15 36.23333333 35.63333333 3116 2732 3178 2675 3008.666667 0.04061923 0.159629197 04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04920///Adipocytokine signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0055100///adiponectin binding+++GO:0097003///adipokinetic hormone receptor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0007584///response to nutrient+++GO:0009617///response to bacterium+++GO:0009750///response to fructose+++GO:0009755///hormone-mediated signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0014075///response to amine+++GO:0019395///fatty acid oxidation+++GO:0030308///negative regulation of cell growth+++GO:0031667///response to nutrient levels+++GO:0032496///response to lipopolysaccharide+++GO:0033211///adiponectin-activated signaling pathway+++GO:0042493///response to drug+++GO:0042593///glucose homeostasis+++GO:0045471///response to ethanol+++GO:0046326///positive regulation of glucose import+++GO:0061042///vascular wound healing+++GO:0061871///negative regulation of hepatic stellate cell migration+++GO:0071398///cellular response to fatty acid+++GO:0120162///positive regulation of cold-induced thermogenesis 68468 68468 'Ly6g6c' mRNA 27 36 28 1.82 2.4 2 6.58 5.6 6.74 2.073333333 6.306666667 112 93 111 30.33333333 105.3333333 1.08E-08 1.785280756 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0032991///protein-containing complex GO:0042802///identical protein binding GO:0009617///response to bacterium 68472 68472 'Tmem126b' mRNA 321 334 343 24.93 25.7 28.27 33.78 35.16 32.87 26.3 33.93666667 498 505 468 332.6666667 490.3333333 3.21E-05 0.546664492 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 68473 68473 'Mob1b' mRNA 300 279 207 5.18 4.74 3.79 6.06 5.8 6.07 4.57 5.976666667 404 378 392 262 391.3333333 2.13E-04 0.572362784 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016301///kinase activity+++GO:0019209///kinase activator activity+++GO:0019900///kinase binding+++GO:0030295///protein kinase activator activity+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0031952///regulation of protein autophosphorylation+++GO:0033674///positive regulation of kinase activity+++GO:0035329///hippo signaling 68475 68475 'Ssna1' mRNA 1162 1122 1126 89.45 85.53 91.98 89.25 97.63 87.68 88.98666667 91.52 1328 1415 1260 1136.666667 1334.333333 0.019057512 0.219553449 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body GO:0042802///identical protein binding GO:0042073///intraciliary transport+++GO:0060830///ciliary receptor clustering involved in smoothened signaling pathway 68477 68477 'Rmnd5a' mRNA 848 880 798 8.3 8.52 8.33 7.28 5.97 6.96 8.383333333 6.736666667 855 661 774 842 763.3333333 0.196872634 -0.154087682 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0034657///GID complex GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 68479 68479 'Phf5a' mRNA 850 832 773 30.07 29.02 29.01 34.23 36.78 34.14 29.36666667 35.05 1112 1166 1073 818.3333333 1117 1.55E-06 0.438612177 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048863///stem cell differentiation" 68480 68480 'Card19' mRNA 1054 1188 699 89.39 99.79 62.89 96.6 117.95 107.51 84.02333333 107.3533333 1306 1552 1403 980.3333333 1420.333333 8.34E-05 0.535228813 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0042981///regulation of apoptotic process 68481 68481 'Mpzl1' mRNA 6283 6600 6291 151.75 156.62 160.61 128.2 128.85 124.94 156.3266667 127.33 6124 6009 5783 6391.333333 5972 0.075566934 -0.109985513 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007165///signal transduction+++GO:0030335///positive regulation of cell migration 68487 68487 'Tmem140' mRNA 581.26 568.71 467.06 15.84 15.07 13.09 26.74 24.37 27.71 14.66666667 26.27333333 1206.2 1038.29 1148.54 539.01 1131.01 1.97E-26 1.060290317 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68490 68490 'Zfp579' mRNA 808 870 667 14.01 14.9 12.26 8.98 8.04 7.87 13.72333333 8.296666667 592 520 500 781.6666667 537.3333333 1.56E-06 -0.549128139 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 68493 68493 'Ndufaf4' mRNA 594 685 634 8.87 10.07 10.05 9.27 9.41 8.46 9.663333333 9.046666667 714 708 631 637.6666667 684.3333333 0.515225421 0.089869251 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function+++GO:0005516///calmodulin binding GO:0008284///positive regulation of cell proliferation+++GO:0010257///NADH dehydrogenase complex assembly+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0043066///negative regulation of apoptotic process+++GO:0051607///defense response to virus 68497 68497 'Arel1' mRNA 778 818 751 7.96 8.2 8.27 9.25 7.46 8.09 8.143333333 8.266666667 1051 830 887 782.3333333 922.6666667 0.041604587 0.224993148 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0050727///regulation of inflammatory response 68498 68498 'Tspan11' mRNA 8 9 12 0.09 0.11 0.16 0.64 0.36 0.49 0.12 0.496666667 61 32 44 9.666666667 45.66666667 2.77E-05 2.21776361 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0016477///cell migration 68499 68499 'Mrpl53' mRNA 402 372 374 48.81 44.94 48.2 55.74 57.77 59.59 47.31666667 57.7 524 528 540 382.6666667 530.6666667 1.99E-04 0.46013789 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function GO:0008150///biological_process 68501 68501 'Nsmce2' mRNA 590 596 604 29.25 28.2 29.78 27.47 32.58 33.35 29.07666667 31.13333333 646 727 735 596.6666667 702.6666667 0.06721736 0.224357357 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0030915///Smc5-Smc6 complex" GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0061665///SUMO ligase activity GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0090398///cellular senescence 68505 68505 'Vps51' mRNA 1216 1206 1222 25.64 25.03 27.33 21.87 21.76 21.89 26 21.84 1193 1159 1156 1214.666667 1169.333333 0.518785108 -0.067736014 GO:0000938///GARP complex+++GO:0005730///nucleolus+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:1990745///EARP complex GO:0003674///molecular_function "GO:0006869///lipid transport+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0007041///lysosomal transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0048854///brain morphogenesis" 68507 68507 'Ppfia4' mRNA 620 648 624 5.41 5.56 5.78 3.09 3.47 3.41 5.583333333 3.323333333 408 447 436 630.6666667 430.3333333 1.50E-06 -0.562571769 GO:0045202///synapse+++GO:0048786///presynaptic active zone GO:0005515///protein binding GO:0050808///synapse organization 68509 68509 'Ptx4' mRNA 0 0 1 0 0 0.04 0.03 0 0.04 0.013333333 0.023333333 1 0 1 0.333333333 0.666666667 0.863090843 0.873488313 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 68510 68510 'Ints1' mRNA 785 891 762 5.81 6.49 5.99 5.72 5.35 5.51 6.096666667 5.526666667 889 813 830 812.6666667 844 0.741931501 0.043896539 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0001832///blastocyst growth+++GO:0001833///inner cell mass cell proliferation+++GO:0016180///snRNA processing+++GO:0034474///U2 snRNA 3'-end processing+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 68511 68511 'Dcdc2c' mRNA 281.71 233.88 213.07 11.69 9.57 9.38 7.55 6.58 7.56 10.21333333 7.23 208.84 177.77 202.41 242.8866667 196.34 0.097373406 -0.318684157 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process+++GO:0035556///intracellular signal transduction 68512 68512 'Tomm5' mRNA 535 522 500 62.22 60.47 61.67 89.03 94.35 87.97 61.45333333 90.45 875 901 832 519 869.3333333 4.79E-13 0.733178491 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006626///protein targeting to mitochondrion+++GO:0015031///protein transport 68514 68514 'Micu2' mRNA 1445 1478 1312 35.03 35.27 33.74 28.05 33.78 34.07 34.68 31.96666667 1331 1564 1566 1411.666667 1487 0.569330972 0.066745543 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0034704///calcium channel complex+++GO:1990246///uniplex complex GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0051562///negative regulation of mitochondrial calcium ion concentration 68515 68515 'Myadml2' mRNA 9 6 9 0.26 0.16 0.23 0.02 0.17 0.09 0.216666667 0.093333333 1 8 3 8 4 0.422516481 -1.00609533 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68519 68519 'Eml1' mRNA 946 1130 772 13 15.13 11.32 6.59 8.02 7.2 13.15 7.27 553 638 582 949.3333333 591 2.55E-08 -0.687618799 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007052///mitotic spindle organization+++GO:0007405///neuroblast proliferation+++GO:0007420///brain development 68520 68520 'Zfyve21' mRNA 1889 2036 1881 86.64 92.32 91.5 64.08 61.48 61.95 90.15333333 62.50333333 1601 1497 1494 1935.333333 1530.666667 2.13E-06 -0.350276756 GO:0005575///cellular_component+++GO:0005768///endosome+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 68521 68521 'Fam189b' mRNA 1206 1333 1098 20.7 22.43 19.98 7.44 8.1 7.01 21.03666667 7.516666667 496 537 449 1212.333333 494 3.48E-37 -1.303624899 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0050699///WW domain binding GO:0008150///biological_process 68523 68523 'Ciao2b' mRNA 445 472 402 47.31 49.86 45.36 49.87 59.3 54.02 47.51 54.39666667 536 620 560 439.6666667 572 0.00341112 0.371415199 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0071817///MMXD complex+++GO:0097361///CIA complex GO:0003674///molecular_function GO:0007059///chromosome segregation+++GO:0016226///iron-sulfur cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer 68524 68524 'Wipf2' mRNA 725.73 672.49 604.01 5.04 4.59 4.45 3.01 2.62 3.09 4.693333333 2.906666667 500.11 423.89 497.16 667.41 473.72 1.66E-05 -0.505395797 04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane GO:0003779///actin binding GO:0030048///actin filament-based movement 68525 68525 'Evc2' mRNA 695 697 654 9.01 8.94 9.06 6.48 5.78 5.03 9.003333333 5.763333333 571 498 430 682 499.6666667 1.64E-04 -0.461403211 04340///Hedgehog signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0098797///plasma membrane protein complex GO:0005515///protein binding GO:0007224///smoothened signaling pathway 68526 68526 'Gpr155' mRNA 2443 2503 2420 32.19 33.27 32.93 10.73 10.57 10.27 32.79666667 10.52333333 915 898 847 2455.333333 886.6666667 8.31E-88 -1.481665248 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0035556///intracellular signal transduction+++GO:0050890///cognition+++GO:0055085///transmembrane transport 68527 68527 'Ucma' mRNA 11865 11839 11669 902.94 891.83 942.94 520.16 525.55 516.83 912.57 520.8466667 7848 7693 7524 11791 7688.333333 2.99E-33 -0.629427583 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0016235///aggresome+++GO:0031012///extracellular matrix+++GO:0031410///cytoplasmic vesicle+++GO:0034774///secretory granule lumen+++GO:0048471///perinuclear region of cytoplasm GO:0005184///neuropeptide hormone activity+++GO:0036122///BMP binding GO:0007218///neuropeptide signaling pathway+++GO:0035176///social behavior+++GO:0036343///psychomotor behavior+++GO:0043207///response to external biotic stimulus+++GO:0045667///regulation of osteoblast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0048706///embryonic skeletal system development+++GO:0060392///negative regulation of SMAD protein signal transduction+++GO:0090277///positive regulation of peptide hormone secretion+++GO:1900738///positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway 68528 68528 'Smim6' mRNA 64 42 57 4.22 2.74 3.99 0.98 0.77 0.95 3.65 0.9 17 13 16 54.33333333 15.33333333 3.98E-05 -1.84193843 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0050840///extracellular matrix binding GO:0001974///blood vessel remodeling+++GO:0003151///outflow tract morphogenesis+++GO:0007519///skeletal muscle tissue development+++GO:0030198///extracellular matrix organization+++GO:0030833///regulation of actin filament polymerization+++GO:0043149///stress fiber assembly+++GO:1901877///negative regulation of calcium ion binding+++GO:1901895///negative regulation of calcium-transporting ATPase activity 68533 68533 'Mphosph6' mRNA 381 382 431 21.47 21.28 25.79 26.3 25.06 23.7 22.84666667 25.02 535 497 466 398 499.3333333 0.027292543 0.311451125 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0003723///RNA binding GO:0000460///maturation of 5.8S rRNA+++GO:0006364///rRNA processing 68537 68537 'Mrpl13' mRNA 779 754 752 67.91 65.17 69.57 78.46 81.37 79.14 67.55 79.65666667 1030 1040 1003 761.6666667 1024.333333 8.68E-06 0.415542094 03010///Ribosome GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0017148///negative regulation of translation 68539 68539 'Tmem109' mRNA 2952 3087 2993 87.4 89.86 93.96 83.19 87.1 84.35 90.40666667 84.88 3236 3303 3172 3010.666667 3237 0.217196953 0.092584168 GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031965///nuclear membrane+++GO:0033017///sarcoplasmic reticulum membrane GO:0005244///voltage-gated ion channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0060548///negative regulation of cell death+++GO:0071480///cellular response to gamma radiation 68544 68544 'Trir' mRNA 803 760 167 59.43 55.73 13.11 15.89 27.5 29.07 42.75666667 24.15333333 246 417 435 576.6666667 366 0.450174355 -0.634139968 GO:0005575///cellular_component GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0016787///hydrolase activity "GO:0016075///rRNA catabolic process+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 68545 68545 'Ecscr' mRNA 468 496 453 27.92 29.51 28.73 30.82 29.95 29.92 28.72 30.23 594 559 553 472.3333333 568.6666667 0.032040672 0.256418804 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:0006935///chemotaxis+++GO:0007275///multicellular organism development+++GO:0016525///negative regulation of angiogenesis+++GO:0030154///cell differentiation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:2000353///positive regulation of endothelial cell apoptotic process 68549 68549 'Sgo2a' mRNA 13 28 15 0.14 0.28 0.16 1.24 1.25 1.24 0.193333333 1.243333333 134 140 138 18.66666667 137.3333333 4.11E-18 2.873047314 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0030892///mitotic cohesin complex" GO:0005515///protein binding "GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007140///male meiotic nuclear division+++GO:0007143///female meiotic nuclear division+++GO:0008104///protein localization+++GO:0010789///meiotic sister chromatid cohesion involved in meiosis I+++GO:0045143///homologous chromosome segregation+++GO:0051177///meiotic sister chromatid cohesion+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051754///meiotic sister chromatid cohesion, centromeric+++GO:2000711///positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric" 68550 68550 'Tefm' mRNA 195 216 209 9 9.73 10.25 9.95 9.49 8.01 9.66 9.15 241 232 194 206.6666667 222.3333333 0.696837118 0.092414835 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0030337///DNA polymerase processivity factor activity GO:0006119///oxidative phosphorylation+++GO:0006390///mitochondrial transcription+++GO:0006392///transcription elongation from mitochondrial promoter+++GO:0050790///regulation of catalytic activity 68552 68552 'Smim14' mRNA 4570 4531 4671 60.53 58.96 65.93 66.76 66.07 62.52 61.80666667 65.11666667 5762 5590 5236 4590.666667 5529.333333 1.61E-04 0.254683315 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001835///blastocyst hatching 68553 68553 'Col6a4' mRNA 20 24 15 0.14 0.16 0.11 0.06 0 0.05 0.136666667 0.036666667 9 0 8 19.66666667 5.666666667 0.037201819 -1.808170692 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04974///Protein digestion and absorption+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0031012///extracellular matrix+++GO:0032991///protein-containing complex+++GO:0062023///collagen-containing extracellular matrix GO:0005518///collagen binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization 68554 68554 'Cebpzos' mRNA 708 679 634 51.97 47.6 49.28 43.44 50.91 45.4 49.61666667 46.58333333 683 760 688 673.6666667 710.3333333 0.628527099 0.06676025 GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process 68556 68556 'Uckl1' mRNA 1106 1294 1233 34.27 40.1 41.02 32.48 28.28 29.78 38.46333333 30.18 1195 1013 1054 1211 1087.333333 0.114975419 -0.169572675 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004849///uridine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006222///UMP biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0016310///phosphorylation+++GO:0044206///UMP salvage+++GO:0044211///CTP salvage 68558 68558 'Ankra2' mRNA 532 581 610 14.83 16.19 18.76 12.52 12.5 12.09 16.59333333 12.37 494 487 484 574.3333333 488.3333333 0.058028936 -0.248343684 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:1990393///3M complex GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042826///histone deacetylase binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0010468///regulation of gene expression+++GO:0043254///regulation of protein complex assembly 68559 68559 'Pdrg1' mRNA 2407 2484 2397 119.29 121.47 125.93 103.41 113.4 107.97 122.23 108.26 2395 2562 2420 2429.333333 2459 0.950946368 0.006191434 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0016272///prefoldin complex GO:0003674///molecular_function+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0008150///biological_process 68563 68563 'Dpm3' mRNA 232 250 323 39.72 42.82 58.71 32.07 38.97 37.89 47.08333333 36.31 214 251 242 268.3333333 235.6666667 0.360039584 -0.205057211 00510///N-Glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033185///dolichol-phosphate-mannose synthase complex GO:0008047///enzyme activator activity GO:0006486///protein glycosylation+++GO:0006506///GPI anchor biosynthetic process+++GO:0031647///regulation of protein stability+++GO:0050790///regulation of catalytic activity 68564 68564 'Nufip2' mRNA 1935 1892 2020 9.68 9.3 10.72 9.34 8.78 9.31 9.9 9.143333333 2150 1978 2072 1949 2066.666667 0.468848267 0.070006071 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016604///nuclear body+++GO:0042788///polysomal ribosome GO:0003723///RNA binding 68565 68565 'Mrps18a' mRNA 1155 1068 1086 88.91 81.42 88.71 89.86 98.11 85.18 86.34666667 91.05 1337 1422 1224 1103 1327.666667 0.008555522 0.255684214 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0070181///small ribosomal subunit rRNA binding GO:0006412///translation+++GO:0032543///mitochondrial translation 68566 68566 'Caly' mRNA 5 9 8 0.24 0.43 0.48 0.11 0.76 0.47 0.383333333 0.446666667 2 14 8 7.333333333 8 0.921637661 0.123915534 04728///Dopaminergic synapse GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0098843///postsynaptic endocytic zone+++GO:0098978///glutamatergic synapse+++GO:1904115///axon cytoplasm GO:0032051///clathrin light chain binding+++GO:0044877///protein-containing complex binding GO:0006897///endocytosis+++GO:0007212///dopamine receptor signaling pathway+++GO:0008089///anterograde axonal transport+++GO:0016197///endosomal transport+++GO:0045807///positive regulation of endocytosis+++GO:0048268///clathrin coat assembly+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:1905445///positive regulation of clathrin coat assembly+++GO:2001019///positive regulation of retrograde axon cargo transport 68567 68567 'Cgref1' mRNA 13 11 15 0.64 0.49 0.73 1.93 1.9 2.16 0.62 1.996666667 49 47 53 13 49.66666667 3.64E-05 1.918264123 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007155///cell adhesion+++GO:0030308///negative regulation of cell growth+++GO:0051726///regulation of cell cycle 68572 68572 'Mrpl58' mRNA 1080 1046 1036 69.75 66.55 68.63 60.11 64.93 62.26 68.31 62.43333333 1089 1107 1055 1054 1083.666667 0.821114198 0.02824863 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome "GO:0003747///translation release factor activity+++GO:0004045///aminoacyl-tRNA hydrolase activity+++GO:0016150///translation release factor activity, codon nonspecific+++GO:0016787///hydrolase activity" GO:0006412///translation+++GO:0006415///translational termination+++GO:0070126///mitochondrial translational termination 68576 68576 'Lamtor5' mRNA 1957 1968 1992 146.26 145.62 157.97 166.17 172.17 172.03 149.95 170.1233333 2547 2571 2547 1972.333333 2555 5.44E-07 0.360766569 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0071986///Ragulator complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0060090///molecular adaptor activity GO:0008361///regulation of cell size+++GO:0010628///positive regulation of gene expression+++GO:0032008///positive regulation of TOR signaling+++GO:0032757///positive regulation of interleukin-8 production+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0061462///protein localization to lysosome+++GO:0071230///cellular response to amino acid stimulus+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1904263///positive regulation of TORC1 signaling+++GO:1905636///positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding 68581 68581 'Tmed10' mRNA 7753.92 7709.23 7146.26 119.54 116.92 116.86 162.51 166.29 162.61 117.7733333 163.8033333 12130.98 12125.15 11755.63 7536.47 12003.92 1.02E-41 0.660894413 05130///Pathogenic Escherichia coli infection GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030137///COPI-coated vesicle+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030658///transport vesicle membrane+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042470///melanosome+++GO:0042589///zymogen granule membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070765///gamma-secretase complex GO:0008320///protein transmembrane transporter activity+++GO:0019905///syntaxin binding+++GO:0044877///protein-containing complex binding "GO:0001822///kidney development+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032732///positive regulation of interleukin-1 production+++GO:0035964///COPI-coated vesicle budding+++GO:0043279///response to alkaloid+++GO:0045055///regulated exocytosis+++GO:0048199///vesicle targeting, to, from or within Golgi+++GO:0050714///positive regulation of protein secretion+++GO:0071806///protein transmembrane transport+++GO:1902003///regulation of amyloid-beta formation+++GO:1902960///negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process" 68585 68585 'Rtn4' mRNA 2233.07 2209.29 1673.43 33.87 32.8 27.58 29.04 28.84 29.74 31.41666667 29.20666667 2243.47 2144.78 2221.55 2038.596667 2203.266667 0.288526528 0.105551846 05010///Alzheimer disease GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0044294///dendritic growth cone+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098826///endoplasmic reticulum tubular network membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding GO:0001525///angiogenesis+++GO:0001825///blastocyst formation+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0007029///endoplasmic reticulum organization+++GO:0007399///nervous system development+++GO:0007413///axonal fasciculation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010977///negative regulation of neuron projection development+++GO:0021801///cerebral cortex radial glia guided migration+++GO:0022009///central nervous system vasculogenesis+++GO:0030308///negative regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0033603///positive regulation of dopamine secretion+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0035441///cell migration involved in vasculogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0045687///positive regulation of glial cell differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0048694///positive regulation of collateral sprouting of injured axon+++GO:0050771///negative regulation of axonogenesis+++GO:0050821///protein stabilization+++GO:0051292///nuclear pore complex assembly+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051930///regulation of sensory perception of pain+++GO:0051960///regulation of nervous system development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061462///protein localization to lysosome+++GO:0070571///negative regulation of neuron projection regeneration+++GO:0071456///cellular response to hypoxia+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0090156///cellular sphingolipid homeostasis+++GO:0120078///cell adhesion involved in sprouting angiogenesis+++GO:1902430///negative regulation of amyloid-beta formation+++GO:1902624///positive regulation of neutrophil migration+++GO:1903860///negative regulation of dendrite extension+++GO:1905523///positive regulation of macrophage migration+++GO:1905552///positive regulation of protein localization to endoplasmic reticulum+++GO:1905580///positive regulation of ERBB3 signaling pathway+++GO:1905653///positive regulation of artery morphogenesis+++GO:1905943///negative regulation of formation of growth cone in injured axon+++GO:1990809///endoplasmic reticulum tubular network membrane organization+++GO:2000172///regulation of branching morphogenesis of a nerve+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:2001213///negative regulation of vasculogenesis 68588 68588 'Cthrc1' mRNA 791 805 747 42.14 42.28 42.25 46.04 47.23 45.31 42.22333333 46.19333333 995 993 944 781 977.3333333 8.42E-04 0.312591871 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0017147///Wnt-protein binding "GO:0016477///cell migration+++GO:0032092///positive regulation of protein binding+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0043932///ossification involved in bone remodeling+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0090177///establishment of planar polarity involved in neural tube closure" 68591 68591 'Mocos' mRNA 622 582 698 11.52 10.45 13.84 9.56 10.19 10.09 11.93666667 9.946666667 591 617 602 634 603.3333333 0.580589729 -0.087226505 00790///Folate biosynthesis GO:0005575///cellular_component GO:0003824///catalytic activity+++GO:0008265///Mo-molybdopterin cofactor sulfurase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0030151///molybdenum ion binding+++GO:0030170///pyridoxal phosphate binding+++GO:0102867///molybdenum cofactor sulfurtransferase activity GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0043545///molybdopterin cofactor metabolic process 68592 68592 'Syf2' mRNA 1666 1621 1680 79.26 76.13 84.8 75.8 77.88 73.49 80.06333333 75.72333333 1829 1833 1715 1655.666667 1792.333333 0.269503843 0.101296271 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex "GO:0000398///mRNA splicing, via spliceosome+++GO:0001701///in utero embryonic development+++GO:0006397///mRNA processing+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007369///gastrulation+++GO:0008284///positive regulation of cell proliferation+++GO:0008380///RNA splicing+++GO:0048568///embryonic organ development" 68597 68597 'Ccdc167' mRNA 363.67 389.34 344.38 6.16 6.54 6.61 5.32 6.14 5.21 6.436666667 5.556666667 316.37 317.22 288.71 365.7966667 307.4333333 0.080757027 -0.261350411 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68598 68598 'Dnajc8' mRNA 1551 1575 1663 66.16 66.33 75.58 70.05 75.03 78.29 69.35666667 74.45666667 1879 1967 2031 1596.333333 1959 0.001306277 0.282015353 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0030544///Hsp70 protein binding 68603 68603 'Pmvk' mRNA 1643.35 1458.63 1393 76.62 67.03 69.29 39.49 40.68 40.69 70.98 40.28666667 939.43 930.62 919.41 1498.326667 929.82 3.40E-16 -0.699248635 00900///Terpenoid backbone biosynthesis+++04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004631///phosphomevalonate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0016310///phosphorylation+++GO:0019287///isopentenyl diphosphate biosynthetic process, mevalonate pathway+++GO:0070723///response to cholesterol" 68606 68606 'Ppm1f' mRNA 539 571 490 5.89 6.11 5.64 7.89 7.84 7.08 5.88 7.603333333 831 809 726 533.3333333 788.6666667 2.08E-07 0.554379905 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0043169///cation binding+++GO:0046872///metal ion binding "GO:0006469///negative regulation of protein kinase activity+++GO:0006470///protein dephosphorylation+++GO:0006915///apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0016576///histone dephosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0032880///regulation of protein localization+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0035690///cellular response to drug+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045927///positive regulation of growth+++GO:0050921///positive regulation of chemotaxis+++GO:0051224///negative regulation of protein transport+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:1903827///regulation of cellular protein localization+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin" 68607 68607 'Serhl' mRNA 493.61 445.26 498.82 22.05 19.67 23.59 23.42 27.42 26.35 21.77 25.73 604.19 700.04 667 479.23 657.0766667 5.22E-04 0.444280623 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0016787///hydrolase activity 68611 68611 'Mrpl28' mRNA 1829 2057 1952 108.18 120.25 122.5 116.54 120.92 123.67 116.9766667 120.3766667 2260 2286 2318 1946 2288 0.005403936 0.221548667 03010///Ribosome GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005829///cytosol+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0008150///biological_process 68612 68612 'Ube2c' mRNA 6.05 8.97 13.08 0.42 0.62 0.97 38.33 39.19 39.99 0.67 39.17 627.97 625.57 632.93 9.366666667 628.8233333 5.11E-87 6.112469783 04120///Ubiquitin mediated proteolysis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0010458///exit from mitosis+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031536///positive regulation of exit from mitosis+++GO:0051301///cell division+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination 68614 68614 'Letmd1' mRNA 809.69 721.73 701.52 15.53 13.28 14.78 10.71 10.56 10.39 14.53 10.55333333 611.28 599.43 576.4 744.3133333 595.7033333 0.002329676 -0.332003785 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0043022///ribosome binding 68616 68616 'Gdpd3' mRNA 192 192 199 11.32 11.19 12.45 11.56 10.38 10.85 11.65333333 10.93 225 197 204 194.3333333 208.6666667 0.70945133 0.088626541 00565///Ether lipid metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004622///lysophospholipase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0034638///phosphatidylcholine catabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0070291///N-acylethanolamine metabolic process 68617 68617 'Mtcl1' mRNA 836 802 836 5.19 4.79 5.63 1.77 1.78 1.71 5.203333333 1.753333333 318 322 297 824.6666667 312.3333333 1.82E-35 -1.413844093 GO:0000922///spindle pole+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030496///midbody+++GO:0097427///microtubule bundle GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042803///protein homodimerization activity GO:0001578///microtubule bundle formation+++GO:0010506///regulation of autophagy+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:2000576///positive regulation of microtubule motor activity 68618 68618 'Eola1' mRNA 645 642 604 38.5 37.88 38.26 31.75 32.14 32.85 38.21333333 32.24666667 610 602 610 630.3333333 607.3333333 0.632764537 -0.064671288 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68625 68625 'Cfap57' mRNA 140 179 139 1.88 2.39 1.98 0.26 0.28 0.08 2.083333333 0.206666667 22 23 6 152.6666667 17 1.99E-19 -3.176263222 GO:0003674///molecular_function 68626 68626 'Elac2' mRNA 563 539 490 9.57 8.88 8.63 8.02 8.81 8.27 9.026666667 8.366666667 549 591 544 530.6666667 561.3333333 0.628624794 0.071614854 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0042645///mitochondrial nucleoid GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004549///tRNA-specific ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0042781///3'-tRNA processing endoribonuclease activity+++GO:0046872///metal ion binding "GO:0008033///tRNA processing+++GO:0034414///tRNA 3'-trailer cleavage, endonucleolytic+++GO:0072684///mitochondrial tRNA 3'-trailer cleavage, endonucleolytic" 68628 68628 'Fbxw9' mRNA 734 783 786 22.89 24.06 26 18.45 18.84 20.07 24.31666667 19.12 680 678 716 767.6666667 691.3333333 0.158965235 -0.163969242 "GO:0030687///preribosome, large subunit precursor" 68631 68631 'Cryl1' mRNA 850 911 845 35.97 38.04 37.94 50.74 44.79 49.79 37.31666667 48.44 1377 1186 1307 868.6666667 1290 2.87E-10 0.55807363 00040///Pentose and glucuronate interconversions GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0042803///protein homodimerization activity+++GO:0050104///L-gulonate 3-dehydrogenase activity+++GO:0070403///NAD+ binding" GO:0006631///fatty acid metabolic process 68632 68632 'Myct1' mRNA 23 17 19 0.46 0.33 0.4 0.64 0.73 0.77 0.396666667 0.713333333 37 41 43 19.66666667 40.33333333 0.030337458 1.025442176 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0061484///hematopoietic stem cell homeostasis 68634 68634 'Tm2d3' mRNA 1296 1307 1135 91.42 91.69 84.79 70.94 69.04 67.58 89.3 69.18666667 1147 1085 1059 1246 1097 0.027496058 -0.193649673 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0046331///lateral inhibition 68635 68635 '1110025M09Rik' mRNA 15.82 17.51 14.55 0.4 0.43 0.39 0.24 0.27 0.27 0.406666667 0.26 11.16 12.32 12.2 15.96 11.89333333 0.627566225 -0.402817535 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68636 68636 'Fahd1' mRNA 312 302 297 13.24 12.64 13.37 16.36 15.9 17.22 13.08333333 16.49333333 442.94 419.92 451 303.6666667 437.9533333 1.20E-04 0.514342474 00350///Tyrosine metabolism GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0018773///acetylpyruvate hydrolase activity+++GO:0034545///fumarylpyruvate hydrolase activity+++GO:0046872///metal ion binding+++GO:0047621///acylpyruvate hydrolase activity 68642 68642 'Tmem216' mRNA 607 625 681 37.18 37.64 44.11 28.78 28.13 25.94 39.64333333 27.61666667 539 517 474 637.6666667 510 0.007482764 -0.337491282 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0036038///MKS complex+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 68644 68644 'Abhd14a' mRNA 820 896 864 44.04 46.64 49.42 25.94 25.6 24.8 46.7 25.44666667 553 525 505 860 527.6666667 4.69E-12 -0.717539357 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity 68646 68646 'Nadk2' mRNA 464 541 434 6.86 7.91 6.79 3.59 4.36 4.5 7.186666667 4.15 281 330 332 479.6666667 314.3333333 1.27E-05 -0.617029975 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003951///NAD+ kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity GO:0006741///NADP biosynthetic process+++GO:0016310///phosphorylation+++GO:0019674///NAD metabolic process 68652 68652 'Tab2' mRNA 1100 1160 979 12.52 13.45 11.81 15.98 14.12 15.48 12.59333333 15.19333333 1591 1380 1484 1079.666667 1485 7.92E-08 0.44957305 04010///MAPK signaling pathway+++04013///MAPK signaling pathway - fly+++04064///NF-kappa B signaling pathway+++04214///Apoptosis - fly+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04624///Toll and Imd signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05140///Leishmaniasis+++05145///Toxoplasmosis+++05161///Hepatitis B+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05417///Lipid and atherosclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0000187///activation of MAPK activity+++GO:0007507///heart development+++GO:0032496///response to lipopolysaccharide+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045860///positive regulation of protein kinase activity 68653 68653 'Samm50' mRNA 1835 1776 1751 28.99 27.6 29.34 27.91 28.19 28.4 28.64333333 28.16666667 2033 2006 2004 1787.333333 2014.333333 0.034514016 0.160589085 GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019867///outer membrane GO:0005515///protein binding GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0034622///cellular protein-containing complex assembly+++GO:0042407///cristae formation+++GO:0045040///protein import into mitochondrial outer membrane 68655 68655 'Fndc1' mRNA 71 59 45 0.63 0.51 0.42 0.88 0.74 0.87 0.52 0.83 115 94 110 58.33333333 106.3333333 0.003025051 0.858556594 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016607///nuclear speck+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0001934///positive regulation of protein phosphorylation+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0051223///regulation of protein transport+++GO:0071456///cellular response to hypoxia 68659 68659 'Gask1b' mRNA 299.97 328 345.96 2.37 2.56 2.91 2.82 2.52 2.55 2.613333333 2.63 409 360.87 360.05 324.6433333 376.64 0.218523359 0.20076157 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68662 68662 'Scgb3a1' mRNA 66 56 70 10.77 9.12 11.98 7.99 7.42 7.85 10.62333333 7.753333333 55 51 52 64 52.66666667 0.439995355 -0.297360751 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005125///cytokine activity GO:0007165///signal transduction+++GO:1901741///positive regulation of myoblast fusion 68666 68666 'Svop' mRNA 69 71 81 1.18 1.2 1.48 0.34 0.24 0.32 1.286666667 0.3 23 16 21 73.66666667 20 5.91E-07 -1.898649226 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 68667 68667 'Trpm4' mRNA 720 816 782 9.18 10.3 10.61 6.61 6.25 5.79 10.03 6.216666667 596 548 500 772.6666667 548 7.94E-06 -0.509091234 04911///Insulin secretion GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034706///sodium channel complex+++GO:0043025///neuronal cell body+++GO:0044214///spanning component of plasma membrane+++GO:0089717///spanning component of membrane GO:0000166///nucleotide binding+++GO:0005216///ion channel activity+++GO:0005227///calcium activated cation channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0099604///ligand-gated calcium channel activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002407///dendritic cell chemotaxis+++GO:0002724///regulation of T cell cytokine production+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0016925///protein sumoylation+++GO:0019722///calcium-mediated signaling+++GO:0030502///negative regulation of bone mineralization+++GO:0034220///ion transmembrane transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042310///vasoconstriction+++GO:0042391///regulation of membrane potential+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045907///positive regulation of vasoconstriction+++GO:0051289///protein homotetramerization+++GO:0055085///transmembrane transport+++GO:0061337///cardiac conduction+++GO:0070588///calcium ion transmembrane transport+++GO:0071318///cellular response to ATP+++GO:0086045///membrane depolarization during AV node cell action potential+++GO:0086047///membrane depolarization during Purkinje myocyte cell action potential+++GO:0086048///membrane depolarization during bundle of His cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0098655///cation transmembrane transport+++GO:0098662///inorganic cation transmembrane transport+++GO:0098719///sodium ion import across plasma membrane+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:1903949///positive regulation of atrial cardiac muscle cell action potential+++GO:1904179///positive regulation of adipose tissue development+++GO:1904199///positive regulation of regulation of vascular smooth muscle cell membrane depolarization 68671 68671 'Pcyt2' mRNA 2380 2471 2347 71.52 73.25 74.95 42.48 41.98 38.9 73.24 41.12 1623 1560 1435 2399.333333 1539.333333 3.40E-19 -0.652468197 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism GO:0003824///catalytic activity+++GO:0004306///ethanolamine-phosphate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009058///biosynthetic process 68675 68675 'Fam172a' mRNA 837.03 847.42 805.12 15.9 16.39 16.88 10.96 11.18 11.67 16.39 11.27 697.06 609.46 648.23 829.8566667 651.5833333 3.49E-04 -0.361538187 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0005515///protein binding+++GO:0035197///siRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0014032///neural crest cell development+++GO:0031048///chromatin silencing by small RNA" 68678 68678 'Smtnl1' mRNA 1 1 2 0.03 0.02 0.05 0.02 0.06 0 0.033333333 0.026666667 1 2 0 1.333333333 1 0.876679435 -0.438069914 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0031430///M band+++GO:0031674///I band+++GO:0031941///filamentous actin+++GO:0043292///contractile fiber GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005523///tropomyosin binding+++GO:0008157///protein phosphatase 1 binding+++GO:0017020///myosin phosphatase regulator activity+++GO:0043621///protein self-association+++GO:0051401///CH domain binding+++GO:0097718///disordered domain specific binding "GO:0009410///response to xenobiotic stimulus+++GO:0014823///response to activity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0042310///vasoconstriction+++GO:0042493///response to drug+++GO:0043086///negative regulation of catalytic activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045907///positive regulation of vasoconstriction+++GO:0048644///muscle organ morphogenesis+++GO:0050790///regulation of catalytic activity" 68680 68680 'Fitm1' mRNA 3 3 0 0.22 0.21 0 0.56 0.26 0.19 0.143333333 0.336666667 9 4 3 2 5.333333333 0.380743044 1.419780154 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0017129///triglyceride binding+++GO:0019992///diacylglycerol binding GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0019915///lipid storage+++GO:0034389///lipid droplet organization+++GO:0140042///lipid droplet formation 68682 68682 'Slc44a2' mRNA 7693 8118 8238 117.82 122.26 133.68 74.69 74.87 73.21 124.5866667 74.25666667 5539 5413 5250 8016.333333 5400.666667 4.58E-20 -0.583639893 05231///Choline metabolism in cancer GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0015220///choline transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0015871///choline transport+++GO:0055085///transmembrane transport 68691 68691 'Kansl1l' mRNA 993.2 961.59 941.99 7.1 6.62 7.5 4.37 3.68 4.39 7.073333333 4.146666667 676.29 568.15 673.65 965.5933333 639.3633333 2.04E-09 -0.60756746 GO:0000123///histone acetyltransferase complex+++GO:0044545///NSL complex GO:0035035///histone acetyltransferase binding GO:0008150///biological_process 68693 68693 'Hnrnpul2' mRNA 477 533 404 4.43 4.86 3.98 3.72 3.14 3.26 4.423333333 3.373333333 462 381 392 471.3333333 411.6666667 0.16838937 -0.204248595 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003723///RNA binding+++GO:0005515///protein binding GO:0008150///biological_process 68695 68695 'Hddc3' mRNA 1457.05 1556.22 1474.51 73.41 79.51 80.25 45.8 40.9 43.17 77.72333333 43.29 1065.48 913.14 1013.26 1495.926667 997.2933333 2.22E-12 -0.598059418 00230///Purine metabolism GO:0005575///cellular_component "GO:0008893///guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding" 68701 68701 'Ppp1r27' mRNA 1764 1840 1766 156.71 162.09 166.49 11.8 12.36 12.47 161.7633333 12.21 152 155 155 1790 154 1.87E-245 -3.550938515 GO:0005575///cellular_component GO:0004864///protein phosphatase inhibitor activity+++GO:0019902///phosphatase binding GO:0010923///negative regulation of phosphatase activity+++GO:0043086///negative regulation of catalytic activity 68703 68703 'Rere' mRNA 4492.75 4361.62 3034.2 26.29 25.08 18.32 18.88 17.27 18.49 23.23 18.21333333 3493.34 3151.42 3280.39 3962.856667 3308.383333 0.008885124 -0.264917883 04391///Hippo signaling pathway - fly GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0016605///PML body GO:0001085///RNA polymerase II transcription factor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding "GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0021549///cerebellum development+++GO:0021691///cerebellar Purkinje cell layer maturation+++GO:0021930///cerebellar granule cell precursor proliferation+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048755///branching morphogenesis of a nerve+++GO:0048813///dendrite morphogenesis" 68705 68705 'Gtf2f2' mRNA 272 288 281 10.99 11.51 12.08 12.56 13.62 14 11.52666667 13.39333333 357 377 385 280.3333333 373 0.00667717 0.400475842 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005674///transcription factor TFIIF complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0015630///microtubule cytoskeleton+++GO:0097550///transcriptional preinitiation complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0016787///hydrolase activity GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0032508///DNA duplex unwinding+++GO:0051123///RNA polymerase II preinitiation complex assembly 68708 68708 'Rabl2' mRNA 1263 1385 1223 43.84 47.39 45.2 9.69 10.42 10.2 45.47666667 10.10333333 318 333 323 1290.333333 324.6666667 3.06E-91 -2.000833927 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0012505///endomembrane system+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0097225///sperm midpiece GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0007338///single fertilization+++GO:0008594///photoreceptor cell morphogenesis+++GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly 68709 68709 'Cilp2' mRNA 244 272 229 3.27 3.59 3.26 2.72 2.89 2.43 3.373333333 2.68 233 242 202 248.3333333 225.6666667 0.466379458 -0.147564183 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0030246///carbohydrate binding GO:0008150///biological_process 68713 68713 'Ifitm1' mRNA 562 558 527 73.83 72.81 72.79 635.77 636.57 633.37 73.14333333 635.2366667 5472 5379 5283 549 5378 0 3.281180949 04662///B cell receptor signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0001503///ossification+++GO:0001756///somitogenesis+++GO:0002376///immune system process+++GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0009952///anterior/posterior pattern specification+++GO:0030336///negative regulation of cell migration+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 68718 68718 'Rnf166' mRNA 598 667 308 19.43 21.23 11.03 10.09 11.34 10.19 17.23 10.54 343 384 346 524.3333333 357.6666667 0.007846834 -0.547357938 GO:0005737///cytoplasm GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response 68721 68721 '1110032A03Rik' mRNA 1789.14 1884 1848 45.73 47.37 51.65 18.9 18.39 18.05 48.25 18.44666667 867 818 784.17 1840.38 823.0566667 2.99E-46 -1.174097023 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 68724 68724 'Arl8a' mRNA 515 587 505 16.28 18.28 16.84 17.5 16.69 17.79 17.13333333 17.32666667 632 600 625 535.6666667 619 0.099652127 0.198148279 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0051233///spindle midzone+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport+++GO:0051301///cell division 68725 68725 '1110032F04Rik' mRNA 23 28 3 0.5 0.59 0.07 0.28 0.13 0.15 0.386666667 0.186666667 15 7 8 18 10 0.36581968 -0.837127191 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68728 68728 'Trp53inp2' mRNA 4332 4255 4206 56.5 54.5 58.18 70.04 64.41 66.19 56.39333333 66.88 6066 5440 5546 4264.333333 5684 2.06E-11 0.401409097 04140///Autophagy - animal GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0031410///cytoplasmic vesicle GO:0043130///ubiquitin binding "GO:0000045///autophagosome assembly+++GO:0001649///osteoblast differentiation+++GO:0001894///tissue homeostasis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0010508///positive regulation of autophagy+++GO:0016236///macroautophagy+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1903828///negative regulation of cellular protein localization" 68729 68729 'Trim37' mRNA 1767 1860 1945 20.97 21.79 25.11 10.19 9.77 9.3 22.62333333 9.753333333 1023 921 915 1857.333333 953 2.17E-28 -0.977799303 04120///Ubiquitin mediated proteolysis GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0035098///ESC/E(Z) complex+++GO:0048471///perinuclear region of cytoplasm GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0035518///histone H2A monoubiquitination+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046600///negative regulation of centriole replication+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051865///protein autoubiquitination+++GO:0070842///aggresome assembly" 68730 68730 'Dus1l' mRNA 697 696 683 19.38 19.08 20.6 19.86 19.6 20.3 19.68666667 19.92 826 784 798 692 802.6666667 0.05393116 0.201747407 GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0017150///tRNA dihydrouridine synthase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0002943///tRNA dihydrouridine synthesis+++GO:0008033///tRNA processing 68731 68731 'Rbfa' mRNA 331 352 317 14.88 15.62 15.12 21.57 21.87 21.33 15.20666667 21.59 551 545 527 333.3333333 541 1.44E-08 0.687979273 GO:0005575///cellular_component+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0006364///rRNA processing 68732 68732 'Carmil1' mRNA 3356 3331 3613 34.66 33.8 39.52 12.1 12.67 11.12 35.99333333 11.96333333 1344 1382 1195 3433.333333 1307 7.72E-62 -1.408025072 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0030027///lamellipodium+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0042995///cell projection+++GO:0044354///macropinosome+++GO:0045111///intermediate filament cytoskeleton GO:0044877///protein-containing complex binding GO:0007163///establishment or maintenance of cell polarity+++GO:0016477///cell migration+++GO:0030032///lamellipodium assembly+++GO:0030335///positive regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031529///ruffle organization+++GO:0044351///macropinocytosis+++GO:0046415///urate metabolic process+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051638///barbed-end actin filament uncapping+++GO:0051639///actin filament network formation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1902745///positive regulation of lamellipodium organization+++GO:2000813///negative regulation of barbed-end actin filament capping 68734 68734 'Ppp4r3a' mRNA 1001 962 485 10.95 10.49 5.42 5.9 6.17 6.8 8.953333333 6.29 614 645 688 816 649 0.366371203 -0.326085177 04212///Longevity regulating pathway - worm+++04922///Glucagon signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0030289///protein phosphatase 4 complex GO:0005515///protein binding GO:0006470///protein dephosphorylation+++GO:0045722///positive regulation of gluconeogenesis 68735 68735 'Mrps18c' mRNA 443 450 515 74.6 75.79 92.08 96.7 119.37 110.38 80.82333333 108.8166667 653 782 717 469.3333333 717.3333333 6.18E-06 0.598107166 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0070181///small ribosomal subunit rRNA binding GO:0006412///translation 68736 68736 'Tyw5' mRNA 270.23 268.21 272.8 11.72 11.39 12.55 11.9 10.86 12.17 11.88666667 11.64333333 316.42 282 311.75 270.4133333 303.39 0.387057583 0.153103697 GO:0005575///cellular_component "GO:0000049///tRNA binding+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0102524///tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity" GO:0008033///tRNA processing+++GO:0031591///wybutosine biosynthetic process 68737 68737 'Angel1' mRNA 317.65 392.91 332.86 4.43 5.36 4.73 3.71 4.1 3.39 4.84 3.733333333 310.49 349.68 274.32 347.8066667 311.4966667 0.359868266 -0.167623472 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0000175///3'-5'-exoribonuclease activity+++GO:0003824///catalytic activity+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0019904///protein domain specific binding "GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 68738 68738 'Acss1' mRNA 176 194 168 2.66 2.88 2.69 6.92 7.35 6.66 2.743333333 6.976666667 527 547 491 179.3333333 521.6666667 2.72E-28 1.530587211 00010///Glycolysis / Gluconeogenesis+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0003987///acetate-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016874///ligase activity+++GO:0050218///propionate-CoA ligase activity GO:0006085///acetyl-CoA biosynthetic process+++GO:0019413///acetate biosynthetic process+++GO:0019427///acetyl-CoA biosynthetic process from acetate+++GO:0019542///propionate biosynthetic process 68742 68742 'Tmem219' mRNA 522 540 482 35.29 36.25 34.27 45.83 46.56 46.96 35.27 46.45 776 769 765 514.6666667 770 2.42E-08 0.57096947 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process 68743 68743 'Anln' mRNA 165 173 171 2.56 2.59 2.88 4.53 4.03 4.29 2.676666667 4.283333333 453.91 404 416 169.6666667 424.6366667 5.25E-19 1.309433865 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005826///actomyosin contractile ring+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0030496///midbody+++GO:0032059///bleb+++GO:0042995///cell projection+++GO:0099738///cell cortex region GO:0003779///actin binding GO:0000281///mitotic cytokinesis+++GO:0000915///actomyosin contractile ring assembly+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007049///cell cycle+++GO:0031106///septin ring organization+++GO:0051301///cell division+++GO:0090521///glomerular visceral epithelial cell migration+++GO:1904172///positive regulation of bleb assembly 68744 68744 'Zfp740' mRNA 2006.72 1907.06 1869.48 28.46 26.97 28.78 20.24 18.84 18.79 28.07 19.29 1617.38 1468.44 1424.53 1927.753333 1503.45 1.56E-06 -0.371306868 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 68750 68750 'Rreb1' mRNA 832 804 694 5.45 5.12 4.74 5.1 4.36 5.01 5.103333333 4.823333333 910 755 866 776.6666667 843.6666667 0.370132394 0.109016215 04013///MAPK signaling pathway - fly GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0016607///nuclear speck "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010634///positive regulation of epithelial cell migration+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1903691///positive regulation of wound healing, spreading of epidermal cells+++GO:2000394///positive regulation of lamellipodium morphogenesis" 68753 68753 'Mybphl' mRNA 1 2 0 0.05 0.09 0 0 0 0 0.046666667 0 0 0 0 1 0 0.616323562 -2.415498512 GO:0005737///cytoplasm+++GO:0030017///sarcomere+++GO:0036379///myofilament GO:0001701///in utero embryonic development 68755 68755 'Cgrrf1' mRNA 1037 1135 1162 50.14 54.86 60.04 45.62 47.01 42.62 55.01333333 45.08333333 1071 1071 1002 1111.333333 1048 0.39169731 -0.098523056 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0030308///negative regulation of cell growth+++GO:0051726///regulation of cell cycle 68758 68758 'Abhd11' mRNA 862 853 775 48.14 46.82 46.79 47.28 50.26 47.14 47.25 48.22666667 945 981 920 830 948.6666667 0.06688988 0.182839379 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0016787///hydrolase activity 68760 68760 'Synpo2l' mRNA 22 16 12 0.27 0.19 0.15 0.29 0.14 0.17 0.203333333 0.2 28 12 16 16.66666667 18.66666667 0.863090843 0.15170531 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0016607///nuclear speck+++GO:0030018///Z disc+++GO:0030054///cell junction GO:0003779///actin binding+++GO:0005515///protein binding GO:0003007///heart morphogenesis+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0045214///sarcomere organization+++GO:0051496///positive regulation of stress fiber assembly 68764 68764 'Cdhr3' mRNA 3 3 0 0.05 0.07 0 0.13 0.07 0.07 0.04 0.09 6 4 3 2 4.333333333 0.52449288 1.1255474 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 68767 68767 'Washc1' mRNA 593.04 598.01 429.37 13.7 13.7 10.41 11.36 11.85 12.3 12.60333333 11.83666667 543.99 584.54 564.41 540.14 564.3133333 0.748070175 0.05715295 04144///Endocytosis+++04212///Longevity regulating pathway - worm GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031083///BLOC-1 complex+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0071203///WASH complex GO:0003779///actin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043014///alpha-tubulin binding+++GO:0043015///gamma-tubulin binding+++GO:0050750///low-density lipoprotein particle receptor binding "GO:0001556///oocyte maturation+++GO:0002468///dendritic cell antigen processing and presentation+++GO:0006887///exocytosis+++GO:0007032///endosome organization+++GO:0010467///gene expression+++GO:0010507///negative regulation of autophagy+++GO:0016197///endosomal transport+++GO:0022617///extracellular matrix disassembly+++GO:0030335///positive regulation of cell migration+++GO:0030833///regulation of actin filament polymerization+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031396///regulation of protein ubiquitination+++GO:0032456///endocytic recycling+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0034383///low-density lipoprotein particle clearance+++GO:0034394///protein localization to cell surface+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0042098///T cell proliferation+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0050776///regulation of immune response+++GO:0090306///spindle assembly involved in meiosis+++GO:0099638///endosome to plasma membrane protein transport+++GO:1904109///positive regulation of cholesterol import+++GO:2000010///positive regulation of protein localization to cell surface" 68770 68770 'Phtf2' mRNA 577 637 619 6.49 7.01 7.37 2.47 2.77 2.55 6.956666667 2.596666667 250 239 249 611 246 1.30E-25 -1.325390067 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68774 68774 'Ms4a6d' mRNA 155 149 143 6.78 6.43 6.63 154.29 161.66 156.12 6.613333333 157.3566667 4051.92 4141.82 3965.88 149 4053.206667 0 4.754855403 GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68775 68775 'Atp6v1c2' mRNA 96 83 104 3.76 3.21 4.27 4.97 6.69 5.23 3.746666667 5.63 146 191 151 94.33333333 162.6666667 0.001509023 0.772644174 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0000221///vacuolar proton-transporting V-type ATPase, V1 domain+++GO:0033180///proton-transporting V-type ATPase, V1 domain" "GO:0015078///proton transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:1902600///proton transmembrane transport 68776 68776 'Taf11' mRNA 415.26 388.65 372 18.06 16.28 17.84 17.02 16.01 19.14 17.39333333 17.39 442.14 406 472 391.97 440.0466667 0.293149278 0.156580619 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005794///Golgi apparatus GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0017025///TBP-class protein binding+++GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0047485///protein N-terminus binding "GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0043923///positive regulation by host of viral transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051123///RNA polymerase II preinitiation complex assembly" 68777 68777 'Tmem53' mRNA 942 1068 1019 60.52 67.57 69.06 49.63 51.3 50.3 65.71666667 50.41 888 899 871 1009.666667 886 0.051462481 -0.200771705 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68778 68778 'Gucd1' mRNA 579 605 568 10.92 11.21 11.34 11.43 10.1 10.28 11.15666667 10.60333333 700 604 610 584 638 0.373142767 0.114961914 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68792 68792 'Srpx2' mRNA 148 143 134 2.99 2.99 2.87 4.69 4.53 4.73 2.95 4.65 249 245 251 141.6666667 248.3333333 6.51E-06 0.799061757 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0060076///excitatory synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0097060///synaptic membrane GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0036458///hepatocyte growth factor binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0042325///regulation of phosphorylation+++GO:0048870///cell motility+++GO:0051965///positive regulation of synapse assembly+++GO:0071625///vocalization behavior+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0098609///cell-cell adhesion 68794 68794 'Flnc' mRNA 74 88 91 0.42 0.5 0.55 5.57 6.11 5.42 0.49 5.7 1114 1198 1054 84.33333333 1122 2.00E-154 3.721976879 04010///MAPK signaling pathway+++04510///Focal adhesion+++05132///Salmonella infection+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016528///sarcoplasm+++GO:0030018///Z disc+++GO:0042383///sarcolemma GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0051015///actin filament binding GO:0030029///actin filament-based process+++GO:0030036///actin cytoskeleton organization+++GO:0048747///muscle fiber development+++GO:0055001///muscle cell development 68795 68795 'Ubr3' mRNA 795 820 645 5.19 5.25 4.48 4.11 3.55 3.89 4.973333333 3.85 725 615 665 753.3333333 668.3333333 0.130037254 -0.181500862 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0001701///in utero embryonic development+++GO:0001967///suckling behavior+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007608///sensory perception of smell+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0016567///protein ubiquitination+++GO:0042048///olfactory behavior+++GO:0071596///ubiquitin-dependent protein catabolic process via the N-end rule pathway 68796 68796 'Tmem214' mRNA 1818 1927 1714 36.44 38.28 36.43 40.63 42.88 42.49 37.05 42 2350 2420 2374 1819.666667 2381.333333 5.02E-08 0.378148228 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0008150///biological_process 68797 68797 'Pdgfrl' mRNA 577 539 537 21.97 20.24 21.69 19.92 18.89 19.84 21.3 19.55 601 556 579 551 578.6666667 0.693310926 0.058414803 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 68799 68799 'Rgmb' mRNA 2020 2137 887 25.59 26.46 12.15 8.32 8.77 11.13 21.4 9.406666667 734 767 946 1681.333333 815.6666667 0.009995635 -1.035591663 04350///TGF-beta signaling pathway GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0015026///coreceptor activity+++GO:0042802///identical protein binding "GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0030509///BMP signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated" 68801 68801 'Elovl5' mRNA 3387 3486 3366 67.49 72.37 72.18 64.04 66.16 64.94 70.68 65.04666667 3650 3621 3573 3413 3614.666667 0.324442947 0.070837639 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0097447///dendritic tree GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0045723///positive regulation of fatty acid biosynthetic process" 68802 68802 'Mypn' mRNA 2 2 1 0.02 0.02 0.01 0.01 0 0.03 0.016666667 0.013333333 1 0 3 1.666666667 1.333333333 0.899897199 -0.323871863 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030017///sarcomere+++GO:0030018///Z disc+++GO:0030424///axon+++GO:0031674///I band GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0017124///SH3 domain binding+++GO:0051371///muscle alpha-actinin binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0045214///sarcomere organization+++GO:0070593///dendrite self-avoidance 68810 68810 'Nexn' mRNA 25 21 26 0.51 0.42 0.54 0.61 0.39 0.7 0.49 0.566666667 35 21 39 24 31.66666667 0.5152087 0.382046746 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0030054///cell junction+++GO:0030055///cell-substrate junction+++GO:0030424///axon GO:0003779///actin binding+++GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0009617///response to bacterium+++GO:0030334///regulation of cell migration+++GO:0051493///regulation of cytoskeleton organization+++GO:0070593///dendrite self-avoidance 68813 68813 'Dock5' mRNA 224 247 201 1.13 1.25 1.09 1.3 1.36 1.23 1.156666667 1.296666667 293 300 270 224 287.6666667 0.036424381 0.352104555 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0007264///small GTPase mediated signal transduction+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016477///cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration 68815 68815 'Btbd10' mRNA 738 783 829 13.97 14.85 17.68 18.61 16.67 17.89 15.5 17.72333333 1093 986 1018 783.3333333 1032.333333 2.05E-04 0.383167381 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0042327///positive regulation of phosphorylation+++GO:0044342///type B pancreatic cell proliferation+++GO:1901215///negative regulation of neuron death 68816 68816 'Ppil1' mRNA 403 411 481 20.32 20.47 25.73 33.52 35.59 35.17 22.17333333 34.76 763 790 774 431.6666667 775.6666667 1.56E-11 0.829974259 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0097718///disordered domain specific binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006457///protein folding+++GO:0008380///RNA splicing" 68817 68817 'Ddi2' mRNA 804.22 810.52 279.37 12.35 12.25 4.55 3.72 5.69 6.2 9.716666667 5.203333333 278.55 416.34 449.86 631.37 381.5833333 0.213107246 -0.713344602 GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0016485///protein processing+++GO:0031647///regulation of protein stability+++GO:0072711///cellular response to hydroxyurea+++GO:0097752///regulation of DNA stability 68818 68818 'Zfand2b' mRNA 533 536 493 27.03 26.96 26.64 26.13 24.28 24.12 26.87666667 24.84333333 589 536 526 520.6666667 550.3333333 0.639095842 0.068488702 GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043567///regulation of insulin-like growth factor receptor signaling pathway+++GO:0045047///protein targeting to ER" 68828 68828 'Sync' mRNA 9.08 10.03 4.02 0.23 0.28 0.12 0.9 1.04 1.45 0.21 1.13 38.17 46.31 58.65 7.71 47.71 1.36E-06 2.626270952 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0045103///intermediate filament-based process 68832 68832 'Ldah' mRNA 658.41 704.5 648.1 13.94 14.98 15.42 16.74 15.84 17.16 14.78 16.58 887.35 847.98 871.27 670.3366667 868.8666667 2.07E-04 0.362713985 GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet GO:0016298///lipase activity+++GO:0016787///hydrolase activity GO:0019915///lipid storage+++GO:0090077///foam cell differentiation 68833 68833 'Pdcl3' mRNA 692 761 741 23.54 25.52 26.74 33.77 35.73 34.44 25.26666667 34.64666667 1141 1178 1126 731.3333333 1148.333333 1.43E-11 0.638758912 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0097356///perinucleolar compartment GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0044183///protein binding involved in protein folding GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006457///protein folding+++GO:0006915///apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0030036///actin cytoskeleton organization+++GO:0034605///cellular response to heat+++GO:0045766///positive regulation of angiogenesis+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0061077///chaperone-mediated protein folding+++GO:1903645///negative regulation of chaperone-mediated protein folding+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process 68836 68836 'Mrpl52' mRNA 468 458 595 111.59 110 150.77 127.58 142.3 139.54 124.12 136.4733333 605 653 635 507 631 0.04926405 0.297862832 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 68837 68837 'Foxk2' mRNA 402 327 350 4.34 3.47 4.06 4.42 4.5 4.57 3.956666667 4.496666667 470 466 476 359.6666667 470.6666667 0.006829876 0.376044313 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle "GO:0000287///magnesium ion binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001678///cellular glucose homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010507///negative regulation of autophagy+++GO:0010906///regulation of glucose metabolic process+++GO:0042594///response to starvation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061621///canonical glycolysis" 68839 68839 'Ankrd46' mRNA 1622 1901 1701 36.2 41.61 40.5 34.36 32.16 34.06 39.43666667 33.52666667 1760 1615 1690 1741.333333 1688.333333 0.584562483 -0.056462119 GO:0016020///membrane+++GO:0016021///integral component of membrane 68842 68842 'Tulp4' mRNA 2048.06 1985.37 1592.1 9.9 9.43 8.24 6.02 5.62 6.02 9.19 5.886666667 1422.58 1303.33 1397.02 1875.176667 1374.31 9.09E-08 -0.456317904 GO:0005737///cytoplasm GO:0016567///protein ubiquitination 68845 68845 'Pih1d1' mRNA 519.89 541.64 545.07 28.22 28.62 31.64 36.35 40.33 34.38 29.49333333 37.02 759.84 823.96 694.11 535.5333333 759.3033333 2.38E-05 0.491626344 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0070761///pre-snoRNP complex+++GO:0097255///R2TP complex+++GO:1990904///ribonucleoprotein complex GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042393///histone binding+++GO:0051117///ATPase binding+++GO:0051219///phosphoprotein binding GO:0000492///box C/D snoRNP assembly+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing+++GO:0030855///epithelial cell differentiation+++GO:0031334///positive regulation of protein complex assembly+++GO:0048254///snoRNA localization+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0071169///establishment of protein localization to chromatin+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090240///positive regulation of histone H4 acetylation+++GO:1900110///negative regulation of histone H3-K9 dimethylation+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902661///positive regulation of glucose mediated signaling pathway+++GO:1904263///positive regulation of TORC1 signaling+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:2000619///negative regulation of histone H4-K16 acetylation+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 68846 68846 'Rnf208' mRNA 519 526 321 23.45 23.46 15.39 9.25 10.17 9.89 20.76666667 9.77 235 252 243 455.3333333 243.3333333 1.28E-07 -0.905205412 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination 68852 68852 'Lrrn4cl' mRNA 1197.16 1167.61 1228.71 25.84 24.84 28.02 28.85 28.86 27.41 26.23333333 28.37333333 1535.19 1499.52 1413.85 1197.826667 1482.853333 8.83E-04 0.294375735 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68854 68854 'Asb11' mRNA 0 1 2 0 0.04 0.08 0.67 0.32 0.44 0.04 0.476666667 19 8 12 1 13 0.003990986 3.669997111 GO:0005783///endoplasmic reticulum GO:0003674///molecular_function GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0045732///positive regulation of protein catabolic process 68857 68857 'Dtwd2' mRNA 160.02 183.27 131.94 2.07 2.42 1.88 1.1 1.39 1.5 2.123333333 1.33 92.92 105.81 126.04 158.41 108.2566667 0.020844615 -0.558235509 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0016432///tRNA-uridine aminocarboxypropyltransferase activity+++GO:0016740///transferase activity GO:0006400///tRNA modification+++GO:0008033///tRNA processing 68859 68859 'Smim1' mRNA 1292.43 1404.91 1192.75 30.32 29.7 28.58 19.85 19.54 18.91 29.53333333 19.43333333 987.94 892.47 901.1 1296.696667 927.17 8.21E-09 -0.494242974 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042803///protein homodimerization activity GO:0008150///biological_process 68861 68861 'Dipk2a' mRNA 213 249 252 2.91 3.35 3.66 2.53 2.44 2.42 3.306666667 2.463333333 213 201 197 238 203.6666667 0.224872199 -0.239043374 GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function "GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0048199///vesicle targeting, to, from or within Golgi+++GO:0060038///cardiac muscle cell proliferation+++GO:1900020///positive regulation of protein kinase C activity" 68865 68865 'Arv1' mRNA 1087 1109 957.39 8.52 8.59 8.05 2.82 2.14 2.81 8.386666667 2.59 409.23 308.57 400.92 1051.13 372.9066667 1.49E-40 -1.508145603 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032541///cortical endoplasmic reticulum GO:0003674///molecular_function GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006869///lipid transport+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008206///bile acid metabolic process+++GO:0016125///sterol metabolic process+++GO:0030301///cholesterol transport+++GO:0032366///intracellular sterol transport+++GO:0032383///regulation of intracellular cholesterol transport+++GO:0090181///regulation of cholesterol metabolic process+++GO:0097036///regulation of plasma membrane sterol distribution 68867 68867 'Rnf122' mRNA 547.23 535.31 555.01 5.39 5.18 5.79 3.23 3.53 3.36 5.453333333 3.373333333 377.9 403 380.99 545.85 387.2966667 4.71E-05 -0.509446882 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0043065///positive regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination 68870 68870 'Ak8' mRNA 332 420 354 12.04 15.08 13.87 1.88 1.7 1.9 13.66333333 1.826666667 63 53 58 368.6666667 58 2.63E-43 -2.679507945 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0036126///sperm flagellum+++GO:0097729///9+2 motile cilium GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004127///cytidylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019205///nucleobase-containing compound kinase activity GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0021591///ventricular system development+++GO:0046940///nucleoside monophosphate phosphorylation 68874 68874 'Klhdc9' mRNA 229.14 255.74 179.94 8.66 9.53 7.22 4.14 3.89 3.66 8.47 3.896666667 125.7 115.36 107.64 221.6066667 116.2333333 3.07E-06 -0.940594247 GO:0005575///cellular_component GO:0030332///cyclin binding GO:0008150///biological_process 68875 68875 'Tmcc2' mRNA 3105 3274 3323 49.52 51.86 56.07 6.72 8.38 8.34 52.48333333 7.813333333 506 552 561 3234 539.6666667 2.01E-201 -2.596011985 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0042982///amyloid precursor protein metabolic process 68876 68876 'Atp23' mRNA 107 114 136 5.43 5.75 7.62 5.89 6.94 8.57 6.266666667 7.133333333 131 145 180 119 152 0.199872454 0.337872354 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0034982///mitochondrial protein processing 68877 68877 'Maf1' mRNA 4162 4373 4236 142.78 148.03 154.33 86.82 89.26 87.47 148.38 87.85 2901 2916 2837 4257 2884.666667 5.52E-20 -0.573631294 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0060077///inhibitory synapse GO:0000994///RNA polymerase III core binding+++GO:0001002///RNA polymerase III type 1 promoter sequence-specific DNA binding+++GO:0001003///RNA polymerase III type 2 promoter sequence-specific DNA binding+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0050811///GABA receptor binding GO:0016479///negative regulation of transcription by RNA polymerase I+++GO:0016480///negative regulation of transcription by RNA polymerase III 68879 68879 'Prpf6' mRNA 1835 1929 1939 32.95 34.09 36.94 30.95 31.83 31.09 34.66 31.29 1983 1992 1929 1901 1968 0.727489395 0.036963489 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0050681///androgen receptor binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006403///RNA localization+++GO:0008380///RNA splicing+++GO:0045944///positive regulation of transcription by RNA polymerase II" 68888 68888 'Gkn3' mRNA 44 57 39 3.79 4.87 3.57 11.74 14.77 13.02 4.076666667 13.17666667 156 191 167 46.66666667 171.3333333 2.01E-13 1.870742249 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0042127///regulation of cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation 68889 68889 'Ubac2' mRNA 1357 1413 1352 35.63 36.53 37.7 33.49 35.72 32.99 36.62 34.06666667 1466 1528 1400 1374 1464.666667 0.409847043 0.080713825 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding "GO:0016055///Wnt signaling pathway+++GO:0070972///protein localization to endoplasmic reticulum+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 68891 68891 'Cd177' mRNA 35 55 49 0.83 1.3 1.24 0.67 0.58 0.53 1.123333333 0.593333333 35 31.85 29 46.33333333 31.95 0.209397659 -0.56315004 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030667///secretory granule membrane+++GO:0044853///plasma membrane raft+++GO:0046658///anchored component of plasma membrane+++GO:0070821///tertiary granule membrane GO:0002020///protease binding+++GO:0005178///integrin binding+++GO:0048306///calcium-dependent protein binding GO:0002376///immune system process+++GO:0007155///cell adhesion+++GO:0007159///leukocyte cell-cell adhesion+++GO:0030100///regulation of endocytosis+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034394///protein localization to cell surface+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0045087///innate immune response+++GO:0045217///cell-cell junction maintenance+++GO:0072672///neutrophil extravasation+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:2001044///regulation of integrin-mediated signaling pathway 68895 68895 'Rasl11a' mRNA 23 18 21 1.27 0.98 1.23 2.07 1.68 1.44 1.16 1.73 43 34 29 20.66666667 35.33333333 0.138048714 0.758078053 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0007165///signal transduction+++GO:0045943///positive regulation of transcription by RNA polymerase I 68897 68897 'Disp1' mRNA 448 510 472 4.8 5.37 5.35 4.27 3.81 4.14 5.173333333 4.073333333 459 400 429 476.6666667 429.3333333 0.25111296 -0.163585236 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0016020///membrane+++GO:0016021///integral component of membrane GO:1904680///peptide transmembrane transporter activity GO:0007224///smoothened signaling pathway+++GO:0007225///patched ligand maturation+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007389///pattern specification process+++GO:0009880///embryonic pattern specification+++GO:0009953///dorsal/ventral pattern formation+++GO:0015833///peptide transport+++GO:0042886///amide transport+++GO:0055085///transmembrane transport+++GO:0060539///diaphragm development 68904 68904 'Abhd13' mRNA 455 434 241 4.74 4.47 2.69 2.62 2.68 3.43 3.966666667 2.91 287 287 367 376.6666667 313.6666667 0.242374898 -0.262930431 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032839///dendrite cytoplasm GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity GO:0002084///protein depalmitoylation 68910 68910 'Zfp467' mRNA 771 687 694 35.53 31.05 37 24.81 23.93 21.07 34.52666667 23.27 703 670 616 717.3333333 663 0.314477648 -0.125861702 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 68911 68911 'Pygo2' mRNA 1470 1555 449 27.85 28.8 9.22 11.88 16.76 15.15 21.95666667 14.59666667 709 991 888 1158 862.6666667 0.544819113 -0.40852565 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990907///beta-catenin-TCF complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0035034///histone acetyltransferase regulator activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0002088///lens development in camera-type eye+++GO:0007286///spermatid development+++GO:0007289///spermatid nucleus differentiation+++GO:0007420///brain development+++GO:0030879///mammary gland development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0035065///regulation of histone acetylation+++GO:0035563///positive regulation of chromatin binding+++GO:0048589///developmental growth+++GO:0048856///anatomical structure development+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0060021///roof of mouth development+++GO:0060070///canonical Wnt signaling pathway 68915 68915 'Vars2' mRNA 312 343 285 3.94 4.36 3.85 3.46 3.13 2.52 4.05 3.036666667 329 286 218 313.3333333 277.6666667 0.351880723 -0.185299683 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004832///valine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006438///valyl-tRNA aminoacylation 68916 68916 'Cdkal1' mRNA 1052.06 1145.09 1008.99 19.34 20.07 19.79 10.31 10.68 10.37 19.73333333 10.45333333 682.2 682.94 672.88 1068.713333 679.34 3.09E-13 -0.664838734 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0035596///methylthiotransferase activity+++GO:0035598///N6-threonylcarbomyladenosine methylthiotransferase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0061712///tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase" GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0035600///tRNA methylthiolation+++GO:1990145///maintenance of translational fidelity 68917 68917 'Hint2' mRNA 1280 1257 1286 166.84 163.21 177.94 126.86 147.72 140.91 169.33 138.4966667 1110 1256 1188 1274.333333 1184.666667 0.274056957 -0.116984371 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0043530///adenosine 5'-monophosphoramidase activity GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006915///apoptotic process+++GO:0016042///lipid catabolic process+++GO:2000757///negative regulation of peptidyl-lysine acetylation 68918 68918 '1190005I06Rik' mRNA 278.15 258.13 217.64 26.21 24.13 21.76 7.35 12.06 10.57 24.03333333 9.993333333 89.24 142.48 123.83 251.3066667 118.5166667 2.70E-07 -1.093367692 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68920 68920 '1110065P20Rik' mRNA 220.76 232.1 190.35 20.94 22.14 19.5 18.6 21.88 23.27 20.86 21.25 224.74 253.86 272.01 214.4033333 250.2033333 0.273085598 0.215008503 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68922 68922 'Dnaic1' mRNA 744 768 743 16.83 17.07 17.7 3.15 3.24 3.3 17.2 3.23 159 161 162 751.6666667 160.6666667 4.26E-70 -2.237976408 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036157///outer dynein arm+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0007018///microtubule-based movement+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0008286///insulin receptor signaling pathway+++GO:0030317///flagellated sperm motility+++GO:0036158///outer dynein arm assembly 68925 68925 'Rpap1' mRNA 1402 1569 1400 15.71 17.33 16.61 12.8 11.81 12.39 16.55 12.33333333 1314 1185 1231 1457 1243.333333 0.004659217 -0.240391675 GO:0005634///nucleus+++GO:0030880///RNA polymerase complex GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0006366///transcription by RNA polymerase II 68926 68926 'Ubap2' mRNA 1903 1830 1765 23.4 22.1 23 19.73 20.16 22.28 22.83333333 20.72333333 1849 1839 2020 1832.666667 1902.666667 0.672227822 0.042990092 GO:0005634///nucleus+++GO:0005737///cytoplasm 68927 68927 'Ptcd2' mRNA 532 583 534 18.13 19.6 19 16.3 17.08 17.24 18.91 16.87333333 561 564 570 549.6666667 565 0.863090843 0.02866714 GO:0005739///mitochondrion GO:0001822///kidney development+++GO:0001889///liver development+++GO:0006397///mRNA processing+++GO:0007005///mitochondrion organization+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0010468///regulation of gene expression+++GO:0048747///muscle fiber development+++GO:0050684///regulation of mRNA processing+++GO:0055001///muscle cell development+++GO:0055010///ventricular cardiac muscle tissue morphogenesis 68929 68929 'Mospd3' mRNA 804 782 308 36.69 34.72 14.87 18.26 32.48 28.17 28.76 26.30333333 460 802 685 631.3333333 649 0.934509941 0.053484035 GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0033149///FFAT motif binding GO:0007507///heart development+++GO:0061817///endoplasmic reticulum-plasma membrane tethering+++GO:0090158///endoplasmic reticulum membrane organization 68936 68936 'Smim11' mRNA 643 664 721 108.81 112.11 128.91 86.95 111.04 97.62 116.61 98.53666667 589 725 631 676 648.3333333 0.659405574 -0.073202779 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 68938 68938 'Aspscr1' mRNA 1137 1180 1108 36.55 37.97 37.91 39.07 39.66 40.2 37.47666667 39.64333333 1402 1391 1365 1141.666667 1386 0.001059347 0.268453113 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0012505///endomembrane system+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0031401///positive regulation of protein modification process+++GO:0042593///glucose homeostasis+++GO:0046324///regulation of glucose import 68939 68939 'Rasl11b' mRNA 484 551 509 15.81 17.74 17.64 9.3 9.38 10.75 17.06333333 9.81 327 322 366 514.6666667 338.3333333 2.58E-06 -0.616695582 GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0007165///signal transduction+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway 68942 68942 'Chmp2b' mRNA 1482 1540 1556 45.53 46.92 49.92 59.94 55.5 57.84 47.45666667 57.76 2222 2068 2133 1526 2141 3.98E-10 0.474961285 04144///Endocytosis+++04217///Necroptosis+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000815///ESCRT III complex+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0098978///glutamatergic synapse GO:0019904///protein domain specific binding GO:0006997///nucleus organization+++GO:0007032///endosome organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0045324///late endosome to vacuole transport+++GO:0050890///cognition+++GO:0061952///midbody abscission+++GO:0070050///neuron cellular homeostasis+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0099175///regulation of postsynapse organization+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902188///positive regulation of viral release from host cell 68943 68943 'Pink1' mRNA 5140 5368 1187 121.56 125.02 29.78 21.47 26.09 31.97 92.12 26.51 1044 1239 1505 3898.333333 1262.666667 0.016841694 -1.607770962 04137///Mitophagy - animal+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0044297///cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0097449///astrocyte projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0002020///protease binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0010857///calcium-dependent protein kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0043422///protein kinase B binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:1904841///TORC2 complex binding "GO:0000422///autophagy of mitochondrion+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002082///regulation of oxidative phosphorylation+++GO:0002931///response to ischemia+++GO:0006468///protein phosphorylation+++GO:0006914///autophagy+++GO:0006979///response to oxidative stress+++GO:0007005///mitochondrion organization+++GO:0010310///regulation of hydrogen peroxide metabolic process+++GO:0010629///negative regulation of gene expression+++GO:0010821///regulation of mitochondrion organization+++GO:0016239///positive regulation of macroautophagy+++GO:0016242///negative regulation of macroautophagy+++GO:0016310///phosphorylation+++GO:0016567///protein ubiquitination+++GO:0018105///peptidyl-serine phosphorylation+++GO:0022904///respiratory electron transport chain+++GO:0031396///regulation of protein ubiquitination+++GO:0032226///positive regulation of synaptic transmission, dopaminergic+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0033603///positive regulation of dopamine secretion+++GO:0033605///positive regulation of catecholamine secretion+++GO:0034599///cellular response to oxidative stress+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045727///positive regulation of translation+++GO:0050821///protein stabilization+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0071456///cellular response to hypoxia+++GO:0072655///establishment of protein localization to mitochondrion+++GO:0072656///maintenance of protein location in mitochondrion+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090258///negative regulation of mitochondrial fission+++GO:0097237///cellular response to toxic substance+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0099074///mitochondrion to lysosome transport+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1901215///negative regulation of neuron death+++GO:1901727///positive regulation of histone deacetylase activity+++GO:1902412///regulation of mitotic cytokinesis+++GO:1902902///negative regulation of autophagosome assembly+++GO:1902958///positive regulation of mitochondrial electron transport, NADH to ubiquinone+++GO:1903147///negative regulation of autophagy of mitochondrion+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1903384///negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903852///positive regulation of cristae formation+++GO:1904783///positive regulation of NMDA glutamate receptor activity+++GO:1904881///cellular response to hydrogen sulfide+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 68944 68944 'Tmco1' mRNA 1959.01 2001.55 1951 23.51 23.62 24.83 28.93 27.98 27.97 23.98666667 28.29333333 2775.11 2622.02 2599 1970.52 2665.376667 3.36E-10 0.423319407 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005262///calcium channel activity+++GO:0043022///ribosome binding GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006983///ER overload response+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport 68947 68947 'Chst8' mRNA 1710 1592 1600 49.37 44.24 48.34 8.69 8.59 8.23 47.31666667 8.503333333 346 334 324 1634 334.6666667 1.75E-131 -2.299972857 00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001537///N-acetylgalactosamine 4-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0016486///peptide hormone processing+++GO:0030166///proteoglycan biosynthetic process+++GO:0042446///hormone biosynthetic process 68948 68948 'Fam216a' mRNA 1250.02 1329.03 1340.5 55.08 57.79 62.66 34.65 37.23 34.15 58.51 35.34333333 902.97 946.55 860.82 1306.516667 903.4466667 5.17E-09 -0.546174313 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 68952 68952 'Tlcd3b' mRNA 397 311 291 10.84 8.26 8.51 1.62 1.3 1.49 9.203333333 1.47 65 47 55 333 55.66666667 2.60E-35 -2.591321785 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0046513///ceramide biosynthetic process+++GO:0055088///lipid homeostasis 68953 68953 'Chmp2a' mRNA 2250 2270 2171 155.98 156.55 160.63 167.15 175.5 169.46 157.72 170.7033333 2736 2803 2678 2230.333333 2739 2.57E-05 0.285095424 04144///Endocytosis+++04217///Necroptosis GO:0000785///chromatin+++GO:0000815///ESCRT III complex+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0031902///late endosome membrane GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0031210///phosphatidylcholine binding GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0010324///membrane invagination+++GO:0010458///exit from mitosis+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0031468///nuclear envelope reassembly+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0045184///establishment of protein localization+++GO:0045324///late endosome to vacuole transport+++GO:0046761///viral budding from plasma membrane+++GO:0050792///regulation of viral process+++GO:0051258///protein polymerization+++GO:0051260///protein homooligomerization+++GO:0060548///negative regulation of cell death+++GO:0061952///midbody abscission+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902188///positive regulation of viral release from host cell+++GO:1903543///positive regulation of exosomal secretion+++GO:1903723///negative regulation of centriole elongation 68955 68955 'Srrm4' mRNA 704 708 638 4.95 4.88 4.74 0.61 0.68 0.69 4.856666667 0.66 100 108 111 683.3333333 106.3333333 7.55E-82 -2.693793225 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0042551///neuron maturation+++GO:0043484///regulation of RNA splicing" 68957 68957 'Paqr6' mRNA 5344 5502 5409 213.91 217.2 231.37 116.69 117.89 113.81 220.8266667 116.13 3201 3149 2995 5418.333333 3115 3.27E-40 -0.811305731 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity 68961 68961 'Phkg2' mRNA 782.86 847.24 857.34 26.33 28 30.18 25.8 23.51 23.53 28.17 24.28 867.82 783.86 771.66 829.1466667 807.78 0.706410296 -0.05251724 04020///Calcium signaling pathway+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway GO:0005829///cytosol+++GO:0005964///phosphorylase kinase complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004689///phosphorylase kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation 68964 68964 'Ctc1' mRNA 817 821 806 10.86 10.75 11.74 10.47 9.39 10.24 11.11666667 10.03333333 894 780 835 814.6666667 836.3333333 0.863090843 0.02479754 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:1990879///CST complex" GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0098505///G-rich strand telomeric DNA binding GO:0000723///telomere maintenance+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007568///aging+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0035264///multicellular organism growth+++GO:0045740///positive regulation of DNA replication+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048536///spleen development+++GO:0048538///thymus development+++GO:0048539///bone marrow development+++GO:0051276///chromosome organization+++GO:0071425///hematopoietic stem cell proliferation+++GO:0090399///replicative senescence 68966 68966 'Ngdn' mRNA 803 846 847 41.06 42.72 45.95 48.34 50.57 44.33 43.24333333 47.74666667 1085 1107 962 832 1051.333333 0.001580437 0.324690082 "GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032040///small-subunit processome+++GO:0042995///cell projection" "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006417///regulation of translation" 68968 68968 'Cdan1' mRNA 135 157 160 1.12 1.28 1.41 1.21 1.13 1.46 1.27 1.266666667 168 153 196 150.6666667 172.3333333 0.474352413 0.179795422 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006325///chromatin organization+++GO:0006998///nuclear envelope organization+++GO:0008104///protein localization+++GO:0008156///negative regulation of DNA replication+++GO:0031497///chromatin assembly 68969 68969 'Eif1b' mRNA 2567 2509 2340 183.05 177.08 177.06 128.88 129.98 136.25 179.0633333 131.7033333 2071 2035 2115 2472 2073.666667 9.26E-05 -0.264205743 GO:0016282///eukaryotic 43S preinitiation complex GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding GO:0006412///translation+++GO:0006413///translational initiation+++GO:0008150///biological_process 68970 68970 'Dcaf12' mRNA 1717 1791 1669 29.26 29.24 30.07 30.18 30.37 28.73 29.52333333 29.76 2046 1941 1864 1725.666667 1950.333333 0.031545684 0.164842096 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex "GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0010506///regulation of autophagy+++GO:0016567///protein ubiquitination 68971 68971 'Tamm41' mRNA 198 190 207 10.34 9.93 11.44 13.28 15.21 13.62 10.57 14.03666667 291 322 287 198.3333333 300 5.21E-04 0.584202938 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0032049///cardiolipin biosynthetic process 68972 68972 'Tatdn3' mRNA 200.89 209 203 10.02 10.38 10.74 8.31 9.13 10.21 10.38 9.216666667 190 205 226 204.2966667 207 0.970880597 0.009936621 GO:0005634///nucleus+++GO:0005739///mitochondrion "GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding" GO:0090305///nucleic acid phosphodiester bond hydrolysis 68975 68975 'Med27' mRNA 924 891 809 47.55 42.72 43.66 38.17 36.63 38.59 44.64333333 37.79666667 843 801 836 874.6666667 826.6666667 0.406784181 -0.091773776 04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016592///mediator complex GO:0003713///transcription coactivator activity+++GO:0061630///ubiquitin protein ligase activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045893///positive regulation of transcription, DNA-templated" 68977 68977 'Haghl' mRNA 2951.73 3153.05 2658.54 122.34 129.41 114.94 77.51 78.94 76.72 122.23 77.72333333 2096.49 2051.19 1990.98 2921.106667 2046.22 2.75E-15 -0.523015398 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0004416///hydroxyacylglutathione hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0019243///methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione 68979 68979 'Nol11' mRNA 780 744 744 13.48 12.73 13.7 12.8 13.53 12.41 13.30333333 12.91333333 850 876 798 756 841.3333333 0.203388995 0.142474464 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0034455///t-UTP complex GO:0006364///rRNA processing+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 68980 68980 'Wdr53' mRNA 179 168 185 8.4 8.15 9.79 11.17 12.08 11.09 8.78 11.44666667 256 269 250 177.3333333 258.3333333 0.002901573 0.529513613 GO:0003674///molecular_function GO:0008150///biological_process 68981 68981 'Snrpa1' mRNA 453 490 418 22.08 23.58 21.62 32.66 36.1 31.8 22.42666667 33.52 769 829 724 453.6666667 774 7.82E-12 0.761616713 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007283///spermatogenesis+++GO:0008380///RNA splicing" 68988 68988 'Prpf31' mRNA 933 1059 955 16.25 18.15 17.65 16.64 20.41 19.17 17.35 18.74 1099 1317 1226 982.3333333 1214 0.005305086 0.296097062 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005687///U4 snRNP+++GO:0005690///U4atac snRNP+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0071339///MLL1 complex+++GO:0097526///spliceosomal tri-snRNP complex GO:0003723///RNA binding+++GO:0030621///U4 snRNA binding+++GO:0030622///U4atac snRNA binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0070990///snRNP binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0071166///ribonucleoprotein complex localization" 68991 68991 'Ssu72' mRNA 1739 1872 1797 70.84 75.23 77.67 97.04 93.28 94.85 74.58 95.05666667 2736 2566 2587 1802.666667 2629.666667 2.34E-14 0.532082825 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity GO:0006369///termination of RNA polymerase II transcription+++GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain 68992 68992 'Zfp580' mRNA 369 334 270 20.7 18.72 16.25 10.43 10.4 11.2 18.55666667 10.67666667 213 209 222 324.3333333 214.6666667 2.32E-04 -0.602548551 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0032757///positive regulation of interleukin-8 production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070301///cellular response to hydrogen peroxide 68995 68995 'Mcts1' mRNA 409 440 426 25.29 27 29.26 46.3 46.08 48.16 27.18333333 46.84666667 837 811 835 425 827.6666667 1.86E-19 0.949379919 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0022627///cytosolic small ribosomal subunit GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity GO:0001731///formation of translation preinitiation complex+++GO:0002188///translation reinitiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0032790///ribosome disassembly+++GO:0040008///regulation of growth+++GO:0075522///IRES-dependent viral translational initiation 68999 68999 'Anapc10' mRNA 252 288 225 11.55 13.64 11.63 19.37 18.33 18.26 12.27333333 18.65333333 431 394 396 255 407 3.12E-06 0.665410077 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 69008 69008 'Cab39l' mRNA 3500 3717 3777 63.26 66.11 72.34 34.31 34.24 33.42 67.23666667 33.99 2189 2134 2063 3664.666667 2128.666667 1.14E-28 -0.797588113 04150///mTOR signaling pathway+++04152///AMPK signaling pathway GO:0043539///protein serine/threonine kinase activator activity GO:0035556///intracellular signal transduction+++GO:0071902///positive regulation of protein serine/threonine kinase activity 69009 69009 'Thap7' mRNA 622 617 598 31.17 30.23 31.71 31.7 29.68 30.15 31.03666667 30.51 721 669 677 612.3333333 689 0.168780247 0.158000113 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016607///nuclear speck+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0003677///DNA binding+++GO:0031493///nucleosomal histone binding+++GO:0035064///methylated histone binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0070577///lysine-acetylated histone binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0106153///phosphorylated histone binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035067///negative regulation of histone acetylation+++GO:0045892///negative regulation of transcription, DNA-templated" 69010 69010 'Anapc13' mRNA 770 768 976 171.57 169.64 234.13 139.26 164.89 165.83 191.78 156.66 698 791 802 838 763.6666667 0.333490964 -0.151279684 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 69017 69017 'Prrt2' mRNA 539 510 419 12.17 11.36 10.07 7.6 6.17 7.28 11.2 7.016666667 389 306 359 489.3333333 351.3333333 4.91E-04 -0.487480338 GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0017124///SH3 domain binding GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0035544///negative regulation of SNARE complex assembly+++GO:0050884///neuromuscular process controlling posture+++GO:0099502///calcium-dependent activation of synaptic vesicle fusion+++GO:1905513///negative regulation of short-term synaptic potentiation 69019 69019 'Spcs1' mRNA 2413.27 2325.36 2487.7 153.15 145.93 167.51 191.16 215.1 197.01 155.53 201.09 3453.7 3787.89 3439.77 2408.776667 3560.453333 3.04E-12 0.550665152 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0043022///ribosome binding GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0019068///virion assembly+++GO:0019082///viral protein processing+++GO:0045047///protein targeting to ER 69020 69020 'Zfp707' mRNA 305 327 341 9.36 9.8 10.82 8.15 6.41 7.27 9.993333333 7.276666667 308 238 267 324.3333333 271 0.110244698 -0.275110496 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 69024 69024 'Snx15' mRNA 696 679 646 25.75 24.68 25.24 25.83 24.23 23.64 25.22333333 24.56666667 806 737 713 673.6666667 752 0.195812792 0.146766946 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding GO:0015031///protein transport 69028 69028 'Mitd1' mRNA 330.26 361 362.24 14.82 16.13 17.49 20.32 22.68 23.33 16.14666667 22.11 484.56 546 538 351.1666667 522.8533333 2.71E-05 0.562575231 GO:0005768///endosome+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0019904///protein domain specific binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0032091///negative regulation of protein binding+++GO:0051301///cell division+++GO:0061952///midbody abscission 69029 69029 'Smdt1' mRNA 1721 1659 1658 177.08 167.48 187.11 182.82 199.9 187.17 177.2233333 189.9633333 2011 2127 1980 1679.333333 2039.333333 6.69E-04 0.268557518 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:1990246///uniplex complex GO:0003674///molecular_function GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051560///mitochondrial calcium ion homeostasis 69032 69032 'Lyzl4' mRNA 7 5 3 0.53 0.36 0.21 0.24 0 0.25 0.366666667 0.163333333 3 0 3 5 2 0.418223627 -1.330753586 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003796///lysozyme activity GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0009566///fertilization+++GO:0042742///defense response to bacterium 69034 69034 'Nupr1l' mRNA 84 82 63 10.01 9.57 7.97 4.73 2.9 3.9 9.183333333 3.843333333 46 27 36 76.33333333 36.33333333 0.00207705 -1.081313366 GO:0005634///nucleus GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0009267///cellular response to starvation+++GO:0045786///negative regulation of cell cycle+++GO:0051726///regulation of cell cycle+++GO:0071157///negative regulation of cell cycle arrest 69035 69035 'Zdhhc3' mRNA 1743.17 1880.16 1812.35 27.95 30.02 30.61 29.88 29.12 29.98 29.52666667 29.66 2186.89 1993.73 2091.96 1811.893333 2090.86 0.01352103 0.193196537 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0042803///protein homodimerization activity" "GO:0006605///protein targeting+++GO:0006612///protein targeting to membrane+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0044873///lipoprotein localization to membrane+++GO:0072659///protein localization to plasma membrane+++GO:1902685///positive regulation of receptor localization to synapse+++GO:1903546///protein localization to photoreceptor outer segment" 69036 69036 'Zg16' mRNA 4 1 6 0.42 0.11 0.67 0.09 0.1 0.19 0.4 0.126666667 1 1 2 3.666666667 1.333333333 0.427480609 -1.493761463 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005796///Golgi lumen+++GO:0031410///cytoplasmic vesicle+++GO:0042589///zymogen granule membrane+++GO:0060205///cytoplasmic vesicle lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0070701///mucus layer GO:0030246///carbohydrate binding+++GO:0042834///peptidoglycan binding GO:0001816///cytokine production+++GO:0015031///protein transport+++GO:0032609///interferon-gamma production+++GO:0032633///interleukin-4 production+++GO:0032635///interleukin-6 production+++GO:0032640///tumor necrosis factor production+++GO:0050830///defense response to Gram-positive bacterium+++GO:0052373///negative regulation by organism of entry into other organism involved in symbiotic interaction 69038 69038 'Tmem258' mRNA 942 857 1025 217.93 199.63 251.64 264.05 300.65 307.57 223.0666667 290.7566667 1288 1421 1441 941.3333333 1383.333333 6.66E-07 0.540558371 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0034998///oligosaccharyltransferase I complex+++GO:0043227///membrane-bounded organelle GO:0003674///molecular_function GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation 69046 69046 'Isca1' mRNA 2080 2312 2201 62.14 68.06 69.76 65.47 67.92 66.52 66.65333333 66.63666667 2519 2551 2477 2197.666667 2515.666667 0.018557462 0.182868088 GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0016226///iron-sulfur cluster assembly+++GO:0097428///protein maturation by iron-sulfur cluster transfer 69047 69047 'Atp2c2' mRNA 862 954 957 15.19 16.32 17.77 14.49 14.18 15.57 16.42666667 14.74666667 942 894 982 924.3333333 939.3333333 0.944041344 0.009651138 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0000166///nucleotide binding+++GO:0005388///calcium-transporting ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0015410///manganese-transporting ATPase activity+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006828///manganese ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0061180///mammary gland epithelium development+++GO:0070588///calcium ion transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0090280///positive regulation of calcium ion import 69048 69048 'Slc30a5' mRNA 1322 1414 459 22.8 23.94 8.39 10 17.56 16.27 18.37666667 14.61 666 1145 1053 1065 954.6666667 0.861179337 -0.141265254 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule GO:0005385///zinc ion transmembrane transporter activity+++GO:0008324///cation transmembrane transporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006824///cobalt ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0010043///response to zinc ion+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0098655///cation transmembrane transport 69049 69049 'Nat8f5' mRNA 213 204 213 13.86 13.13 14.71 23.44 24.29 25.84 13.9 24.52333333 413 417 440 210 423.3333333 3.40E-12 0.999067679 00480///Glutathione metabolism GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007369///gastrulation+++GO:0007507///heart development+++GO:0010628///positive regulation of gene expression+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 69051 69051 'Pycr2' mRNA 1246 1321 1286 45.62 47.69 49.95 46.36 47.8 48.12 47.75333333 47.42666667 1455 1464 1461 1284.333333 1460 0.047500182 0.172790166 00330///Arginine and proline metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0004735///pyrroline-5-carboxylate reductase activity+++GO:0016491///oxidoreductase activity GO:0006561///proline biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0034599///cellular response to oxidative stress+++GO:0055129///L-proline biosynthetic process 69053 69053 '1810013L24Rik' mRNA 634 609 589 8.39 7.93 8.27 8.53 7.26 8.49 8.196666667 8.093333333 742 617 715 610.6666667 691.3333333 0.172729359 0.166344736 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69064 69064 'Fuom' mRNA 485.27 467.73 510.79 10.48 9.64 11.11 14.71 16.05 14.51 10.41 15.09 823.42 873.44 781.42 487.93 826.0933333 3.58E-11 0.747215944 GO:0005575///cellular_component "GO:0016853///isomerase activity+++GO:0016857///racemase and epimerase activity, acting on carbohydrates and derivatives+++GO:0036373///L-fucose mutarotase activity+++GO:0042806///fucose binding+++GO:0048029///monosaccharide binding" GO:0005996///monosaccharide metabolic process+++GO:0006004///fucose metabolic process+++GO:0036065///fucosylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0060180///female mating behavior 69065 69065 'Chac1' mRNA 142 159 149 5.31 5.87 5.91 3.88 4.51 3.74 5.696666667 4.043333333 119 135 111 150 121.6666667 0.193693764 -0.313030994 00480///Glutathione metabolism GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0005112///Notch binding+++GO:0016829///lyase activity+++GO:0061928///glutathione specific gamma-glutamylcyclotransferase activity GO:0006751///glutathione catabolic process+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0007219///Notch signaling pathway+++GO:0007399///nervous system development+++GO:0010955///negative regulation of protein processing+++GO:0022008///neurogenesis+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 69066 69066 '1810010H24Rik' mRNA 180.02 168.4 111.29 5.25 5.02 3.66 1.02 1.84 1.6 4.643333333 1.486666667 39 70 66 153.2366667 58.33333333 1.61E-06 -1.38986225 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 69068 69068 'Tcim' mRNA 759 803 736 24.69 25.74 25.4 46.67 42.19 46.53 25.27666667 45.13 1649 1455 1591 766 1565 2.49E-34 1.018904235 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck GO:0005112///Notch binding GO:0002264///endothelial cell activation involved in immune response+++GO:0006915///apoptotic process+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0034605///cellular response to heat+++GO:0043066///negative regulation of apoptotic process+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045746///negative regulation of Notch signaling pathway+++GO:1900020///positive regulation of protein kinase C activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902806///regulation of cell cycle G1/S phase transition+++GO:1903706///regulation of hemopoiesis 69069 69069 'Tmem273' mRNA 10 17 17 0.4 0.67 0.73 15.73 14.86 14.77 0.6 15.12 449 414 408 14.66666667 423.6666667 2.02E-72 4.839735811 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69071 69071 'Tmem97' mRNA 891 781 828 40.26 34.83 39.7 30.58 32.44 28.73 38.26333333 30.58333333 777 804 706 833.3333333 762.3333333 0.24878072 -0.140970213 GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0031965///nuclear membrane GO:0003674///molecular_function GO:0042632///cholesterol homeostasis 69072 69072 'Ebna1bp2' mRNA 1237 1194 1316 22.98 21.83 25.93 18.86 19.54 19.36 23.58 19.25333333 1168 1182 1161 1249 1170.333333 0.321038798 -0.108192204 "GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0034399///nuclear periphery" GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis 69073 69073 'Kdf1' mRNA 1149 1159 995 34.43 34.16 31.95 14.86 18.49 15.35 33.51333333 16.23333333 572 675 567 1101 604.6666667 6.96E-17 -0.872428073 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0003334///keratinocyte development+++GO:0007275///multicellular organism development+++GO:0010482///regulation of epidermal cell division+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0030154///cell differentiation+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0048589///developmental growth+++GO:0060887///limb epidermis development+++GO:0061436///establishment of skin barrier+++GO:2000647///negative regulation of stem cell proliferation 69076 69076 'Triap1' mRNA 540 600 505 31.9 35.04 31.65 37.09 39.15 39.54 32.86333333 38.59333333 720 741 742 548.3333333 734.3333333 1.34E-04 0.412199474 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex GO:0002039///p53 binding+++GO:1990050///phosphatidic acid transporter activity "GO:0006869///lipid transport+++GO:0006915///apoptotic process+++GO:0015914///phospholipid transport+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0034644///cellular response to UV+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097035///regulation of membrane lipid distribution+++GO:0120009///intermembrane lipid transfer+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2001140///positive regulation of phospholipid transport" 69077 69077 'Psmd11' mRNA 2612 2677 2573 86.39 87.21 90.13 106.31 102.41 101.2 87.91 103.3066667 3700 3480 3419 2620.666667 3533 2.12E-11 0.418595845 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005838///proteasome regulatory particle+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex" GO:0005198///structural molecule activity+++GO:0005515///protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043248///proteasome assembly+++GO:0048863///stem cell differentiation 69080 69080 'Gmppa' mRNA 1050 1006 900 35.73 34.48 32.89 44.29 45.01 44.7 34.36666667 44.66666667 1476 1435 1419 985.3333333 1443.333333 2.69E-11 0.540814155 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01240///Biosynthesis of cofactors+++01250///Biosynthesis of nucleotide sugars GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0009058///biosynthetic process 69082 69082 'Zc3h15' mRNA 1155 1112 1140 33.57 31.84 35.15 37.37 34.6 36.2 33.52 36.05666667 1478 1336 1386 1135.666667 1400 8.47E-04 0.28841761 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0046872///metal ion binding GO:0002181///cytoplasmic translation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043547///positive regulation of GTPase activity 69085 69085 'Zcchc9' mRNA 448 494 467 17.42 18.83 19.23 19.73 18.18 20.31 18.49333333 19.40666667 584 527 582 469.6666667 564.3333333 0.043382914 0.252398183 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0010923///negative regulation of phosphatase activity 69089 69089 'Oxa1l' mRNA 619.69 704 640.65 13.61 15.22 14.93 13.5 13.24 13.81 14.58666667 13.51666667 707.22 677.01 700.14 654.78 694.79 0.572915209 0.074761228 03060///Protein export GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0032991///protein-containing complex GO:0032977///membrane insertase activity+++GO:0042803///protein homodimerization activity+++GO:0097177///mitochondrial ribosome binding GO:0009060///aerobic respiration+++GO:0032780///negative regulation of ATPase activity+++GO:0032979///protein insertion into mitochondrial inner membrane from matrix side+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0051205///protein insertion into membrane+++GO:0051262///protein tetramerization+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0090150///establishment of protein localization to membrane 69090 69090 'Ascc1' mRNA 740.88 808.86 798.57 27.6 29.68 31.14 23.43 21.01 21.89 29.47333333 22.11 730.13 632.96 648.27 782.77 670.4533333 0.036830981 -0.237109783 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016607///nuclear speck+++GO:0031594///neuromuscular junction GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding "GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus" 69091 69091 'Vps26b' mRNA 1601.35 1502.21 1436.22 12.31 11.35 11.71 9.55 9.25 9.37 11.79 9.39 1430.43 1354.56 1359.64 1513.26 1381.543333 0.090052397 -0.143047787 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0045335///phagocytic vesicle "GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0071346///cellular response to interferon-gamma" 69094 69094 'Tmem160' mRNA 775 746 210 63.93 61.25 18.49 25.78 67.53 56.82 47.89 50.04333333 357 911 758 577 675.3333333 0.791891257 0.249121667 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69097 69097 'Trim15' mRNA 8 6 5 0.13 0.09 0.11 0.7 0.39 0.37 0.11 0.486666667 35 19 14 6.333333333 22.66666667 0.012952798 1.824829093 GO:0005737///cytoplasm GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0032481///positive regulation of type I interferon production+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1900246///positive regulation of RIG-I signaling pathway+++GO:1901253///negative regulation of intracellular transport of viral material+++GO:1902187///negative regulation of viral release from host cell" 69101 69101 'Ydjc' mRNA 16 15.89 11 0.73 0.72 0.53 3.77 3.18 3.49 0.66 3.48 94.93 78 84.94 14.29666667 85.95666667 1.63E-11 2.598359797 GO:0005575///cellular_component GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0046872///metal ion binding GO:0005975///carbohydrate metabolic process+++GO:0008150///biological_process 69104 69104 'Marchf5' mRNA 954.39 971.55 551.75 22.17 23.56 12.3 17.57 18.1 17.39 19.34333333 17.68666667 857.9 906.43 867.79 825.8966667 877.3733333 0.652564047 0.087596067 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0051020///GTPase binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070585///protein localization to mitochondrion+++GO:0090140///regulation of mitochondrial fission+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090344///negative regulation of cell aging 69106 69106 'Stoml1' mRNA 711 761 782 20.55 21.69 23.98 19 20.68 17.28 22.07333333 18.98666667 760 805 669 751.3333333 744.6666667 0.863090843 -0.026257412 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0045121///membrane raft GO:0008200///ion channel inhibitor activity GO:0006869///lipid transport+++GO:0060395///SMAD protein signal transduction+++GO:1901586///negative regulation of acid-sensing ion channel activity+++GO:1990830///cellular response to leukemia inhibitory factor 69109 69109 'Ccnq' mRNA 562 594 579 28.09 29.32 30.71 26.74 26.79 26.35 29.37333333 26.62666667 614 600 585 578.3333333 599.6666667 0.793454649 0.039853898 GO:0005634///nucleus GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0030295///protein kinase activator activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032147///activation of protein kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity 69113 69113 'Alkbh3' mRNA 679 636 605 31.11 28.3 31.03 31.61 30.75 29.08 30.14666667 30.48 756 728 692 640 725.3333333 0.135021472 0.16941035 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0008198///ferrous iron binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0043734///DNA-N1-methyladenine dioxygenase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051747///cytosine C-5 DNA demethylase activity+++GO:1990930///RNA N1-methyladenosine dioxygenase activity" GO:0006281///DNA repair+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0035552///oxidative single-stranded DNA demethylation+++GO:0035553///oxidative single-stranded RNA demethylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 69116 69116 'Ubr4' mRNA 3250 3177 1913 10.64 10.22 6.64 6.46 7.25 7.64 9.166666667 7.116666667 2274 2494 2605 2780 2457.666667 0.505307229 -0.176736954 05165///Human papillomavirus infection+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 69121 69121 'Chrdl2' mRNA 6 10 3 0.24 0.43 0.14 0.14 0.14 0.07 0.27 0.116666667 4 4 2 6.333333333 3.333333333 0.503026733 -0.920565037 GO:0005576///extracellular region GO:0005515///protein binding GO:0001503///ossification+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0051216///cartilage development 69123 69123 'Eci3' mRNA 11.03 11.9 12.05 0.49 0.52 0.6 1.06 0.68 0.51 0.536666667 0.75 26.92 15.56 12.09 11.66 18.19 0.425805637 0.620772051 00071///Fatty acid degradation+++04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0043231///intracellular membrane-bounded organelle "GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity+++GO:0016853///isomerase activity+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds" GO:0006635///fatty acid beta-oxidation+++GO:0009062///fatty acid catabolic process 69125 69125 'Cnot8' mRNA 3021 3069 3122 77.49 78.02 85.52 46.72 45.2 41.38 80.34333333 44.43333333 2082 1971 1807 3070.666667 1953.333333 6.04E-19 -0.666484862 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006351///transcription, DNA-templated+++GO:0006417///regulation of translation+++GO:0008284///positive regulation of cell proliferation+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 69126 69126 'Rbis' mRNA 978 936 995 144.45 133.88 165.56 151.61 188.11 192.44 147.9633333 177.3866667 941 1064 1076 969.6666667 1027 0.591968724 0.070636124 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0042254///ribosome biogenesis 69129 69129 'Pex11g' mRNA 471 475 423 10.43 10.36 9.9 8.11 9.67 7.83 10.23 8.536666667 387 397 350 456.3333333 378 0.037262607 -0.281632471 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031231///intrinsic component of peroxisomal membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0016559///peroxisome fission+++GO:0044375///regulation of peroxisome size 69131 69131 'Cdk12' mRNA 1109.42 1086.55 795.51 4.93 4.98 3.52 3.78 3.26 4.06 4.476666667 3.7 982.72 800.38 979.16 997.16 920.7533333 0.379662701 -0.121710656 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0002944///cyclin K-CDK12 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0016607///nuclear speck+++GO:0019908///nuclear cyclin-dependent protein kinase holoenzyme complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030332///cyclin binding GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0008380///RNA splicing+++GO:0016310///phosphorylation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0043405///regulation of MAP kinase activity+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation+++GO:0051726///regulation of cell cycle+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:2000737///negative regulation of stem cell differentiation 69134 69134 'Fam25c' mRNA 3 0 2 0.9 0 0.64 1.13 0.5 1.18 0.513333333 0.936666667 5 3 5 1.666666667 4.333333333 0.442894748 1.35413871 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69136 69136 'Tusc1' mRNA 21 18 8 0.92 0.78 0.37 0.61 0.43 0.83 0.69 0.623333333 16 11 21 15.66666667 16 0.97566161 0.031304805 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69137 69137 'Vstm5' mRNA 10 22 21 0.26 0.6 0.59 0.35 0.37 0.18 0.483333333 0.3 16 15 9 17.66666667 13.33333333 0.606734768 -0.423853933 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0021517///ventral spinal cord development+++GO:0046847///filopodium assembly+++GO:0051260///protein homooligomerization+++GO:1904891///positive regulation of excitatory synapse assembly 69142 69142 'Cd209f' mRNA 33.79 30.49 31.23 1.58 1.54 1.64 1.56 1.75 1.62 1.586666667 1.643333333 34.62 38.82 37.04 31.83666667 36.82666667 0.716882874 0.20241629 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005575///cellular_component+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005537///mannose binding+++GO:0030246///carbohydrate binding GO:0008150///biological_process+++GO:0044419///interspecies interaction between organisms 69146 69146 'Gsdmd' mRNA 230 280 252 7.48 8.97 8.69 25.88 26.55 26.1 8.38 26.17666667 915 916 893 254 908 1.88E-56 1.82658811 04613///Neutrophil extracellular trap formation+++04621///NOD-like receptor signaling pathway+++05132///Salmonella infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0061702///inflammasome complex+++GO:0072559///NLRP3 inflammasome complex "GO:0001786///phosphatidylserine binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0022829///wide pore channel activity+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0070300///phosphatidic acid binding+++GO:1901612///cardiolipin binding" GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0012501///programmed cell death+++GO:0031668///cellular response to extracellular stimulus+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0035915///pore formation in membrane of other organism+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0046931///pore complex assembly+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0070269///pyroptosis 69149 69149 'Kbtbd3' mRNA 386 408 410 6.21 6.18 6.56 4.03 3.89 3.98 6.316666667 3.966666667 306 277 266 401.3333333 283 3.00E-04 -0.517825968 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69150 69150 'Snx4' mRNA 1057 1145 1085 24.16 25.77 26.31 35.08 32.26 33.4 25.41333333 33.58 1765 1585 1627 1095.666667 1659 3.79E-13 0.585757971 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005868///cytoplasmic dynein complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031201///SNARE complex+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex GO:0005154///epidermal growth factor receptor binding+++GO:0005158///insulin receptor binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:1990459///transferrin receptor binding+++GO:1990460///leptin receptor binding GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:1903595///positive regulation of histamine secretion by mast cell 69151 69151 'Lzic' mRNA 1070.08 1092 1113.01 32.27 31.2 34.65 24.91 24.69 26.05 32.70666667 25.21666667 937.54 831 867.95 1091.696667 878.83 6.11E-04 -0.327728622 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0008013///beta-catenin binding GO:0010212///response to ionizing radiation 69155 69155 '1810030O07Rik' mRNA 963.83 1028.06 985.1 19.4 20.38 21.03 17.72 16.23 16.68 20.27 16.87666667 1014 906.58 923 992.33 947.86 0.482458267 -0.078897109 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69156 69156 'Comtd1' mRNA 305.94 288.69 232.95 7.68 7.14 6.21 12.59 13.88 13.48 7.01 13.31666667 576.81 620.71 597.54 275.86 598.3533333 9.25E-18 1.112829964 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity GO:0032259///methylation 69159 69159 'Rhebl1' mRNA 183 192 139 9.4 9.85 7.58 6.43 6.19 4.24 8.943333333 5.62 140 133 92 171.3333333 121.6666667 0.038704669 -0.500905159 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0031929///TOR signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 69161 69161 'Manbal' mRNA 687 637 579 38.76 35.52 34.66 35.7 32.44 34.5 36.31333333 34.21333333 726 643 678 634.3333333 682.3333333 0.462852057 0.094524694 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008150///biological_process 69162 69162 'Sec31a' mRNA 3367.01 3348.26 2440.05 44.89 44.12 34.23 36.54 41.55 37.78 41.08 38.62333333 3181.31 3478.59 3132.38 3051.773333 3264.093333 0.400891025 0.092788596 04141///Protein processing in endoplasmic reticulum GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030120///vesicle coat+++GO:0030127///COPII vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site GO:0005198///structural molecule activity+++GO:0048306///calcium-dependent protein binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051592///response to calcium ion+++GO:0090110///cargo loading into COPII-coated vesicle 69163 69163 'Mrpl44' mRNA 554 582 571 23.18 24.02 25.34 23.31 22.85 22.29 24.18 22.81666667 640 612 592 569 614.6666667 0.457594631 0.098664917 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0016604///nuclear body GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004525///ribonuclease III activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity "GO:0006396///RNA processing+++GO:0010468///regulation of gene expression+++GO:0016075///rRNA catabolic process+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031053///primary miRNA processing+++GO:0031054///pre-miRNA processing+++GO:0070125///mitochondrial translational elongation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 69165 69165 'Cd209b' mRNA 5 3 2 0.14 0.09 0.13 0.1 0 0 0.12 0.033333333 4 0 0 3.333333333 1.333333333 0.544049118 -1.3457122 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0001872///(1->3)-beta-D-glucan binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding "GO:0001879///detection of yeast+++GO:0006897///endocytosis+++GO:0006910///phagocytosis, recognition+++GO:0006955///immune response+++GO:0016045///detection of bacterium+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042102///positive regulation of T cell proliferation+++GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell+++GO:0050766///positive regulation of phagocytosis+++GO:0097323///B cell adhesion+++GO:1903902///positive regulation of viral life cycle" 69168 69168 'Bola1' mRNA 584 607 621 53.64 56.02 60.44 39.33 41.17 38.9 56.7 39.8 481 496 468 604 481.6666667 0.004987419 -0.339513755 GO:0005739///mitochondrion GO:0003674///molecular_function 69169 69169 'Fcmr' mRNA 4 0 0 0.16 0 0 0 0 0 0.053333333 0 0 0 0 1.333333333 0 0.535994789 -2.842745962 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0002376///immune system process+++GO:0070229///negative regulation of lymphocyte apoptotic process+++GO:1990001///inhibition of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 69171 69171 'Cnppd1' mRNA 1462 1601 1334 37.32 40.44 36.33 48.99 48.85 46.46 38.03 48.1 2114 2070 1965 1465.666667 2049.666667 2.70E-10 0.474483841 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity 69178 69178 'Snx5' mRNA 2206 2241 2238 50.6 50.67 54.43 78.78 75.86 77.2 51.9 77.28 3979 3741 3791 2228.333333 3837 1.42E-33 0.770925065 04144///Endocytosis GO:0001726///ruffle+++GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030904///retromer complex+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070685///macropinocytic cup+++GO:0097422///tubular endosome "GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0031748///D1 dopamine receptor binding+++GO:0034452///dynactin binding+++GO:0035091///phosphatidylinositol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0006907///pinocytosis+++GO:0007174///epidermal growth factor catabolic process+++GO:0015031///protein transport+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045776///negative regulation of blood pressure+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046628///positive regulation of insulin receptor signaling pathway" 69179 69179 'Stimate' mRNA 378 375 205 5.47 5.34 3.21 2.38 2.98 2.59 4.673333333 2.65 189 231 199 319.3333333 206.3333333 0.003415068 -0.627963126 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032541///cortical endoplasmic reticulum GO:0005246///calcium channel regulator activity GO:0032237///activation of store-operated calcium channel activity+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 69181 69181 'Dyrk2' mRNA 519 492 496 5.23 4.81 5.09 3.27 3.36 3.2 5.043333333 3.276666667 407 399 363 502.3333333 389.6666667 0.003172436 -0.378826796 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:1990904///ribonucleoprotein complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007224///smoothened signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 69183 69183 'C1qtnf2' mRNA 28 29 21 1.42 1.45 1.13 1.19 1.49 2.01 1.333333333 1.563333333 26 33 44 26 34.33333333 0.472238276 0.397181414 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0000187///activation of MAPK activity+++GO:0019216///regulation of lipid metabolic process+++GO:0043410///positive regulation of MAPK cascade+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0046326///positive regulation of glucose import 69185 69185 'Dtwd1' mRNA 309 299 250 13.06 12.84 11.5 9.04 8.66 8.08 12.46666667 8.593333333 238 219 205 286 220.6666667 0.022978331 -0.383359748 GO:0005634///nucleus GO:0016432///tRNA-uridine aminocarboxypropyltransferase activity+++GO:0016740///transferase activity GO:0006400///tRNA modification+++GO:0008033///tRNA processing 69186 69186 'Tmem256' mRNA 1371 1366 1597 261.08 257.41 319.98 290.09 338.81 338.63 279.49 322.51 1692 1910 1910 1444.666667 1837.333333 0.00210137 0.331721185 GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69187 69187 'Erp27' mRNA 0 1 4 0 0.07 0.23 0.12 0.25 0.26 0.1 0.21 2 5 4 1.666666667 3.666666667 0.582091829 1.096434682 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003756///protein disulfide isomerase activity GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0018215///protein phosphopantetheinylation+++GO:0034976///response to endoplasmic reticulum stress 69188 69188 'Kmt2e' mRNA 5020.16 5061.06 4782.52 34.22 33.75 34.9 24.5 22.59 23.42 34.29 23.50333333 4130.61 3741.61 3838.61 4954.58 3903.61 4.58E-10 -0.356267697 00310///Lysine degradation GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0035327///transcriptionally active chromatin GO:0003713///transcription coactivator activity+++GO:0019899///enzyme binding+++GO:0035064///methylated histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0046872///metal ion binding "GO:0002446///neutrophil mediated immunity+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0030218///erythrocyte differentiation+++GO:0042119///neutrophil activation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0051568///histone H3-K4 methylation+++GO:0051726///regulation of cell cycle+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1905437///positive regulation of histone H3-K4 trimethylation" 69189 69189 'Mcemp1' mRNA 18 7 15 0.99 0.38 0.87 6.7 6.77 5.84 0.746666667 6.436666667 140 138 118 13.33333333 132 9.32E-20 3.29240928 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0008150///biological_process 69190 69190 'Dym' mRNA 1394 1327 1320 31.34 29.35 31.45 18.65 19.6 18.63 30.71333333 18.96 954 980 925 1347 953 2.46E-09 -0.510942509 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0019899///enzyme binding GO:0007030///Golgi organization+++GO:0060348///bone development 69191 69191 'Pdia2' mRNA 8 6 6 0.27 0.21 0.22 0 0.06 0.15 0.233333333 0.07 0 2 5 6.666666667 2.333333333 0.290143217 -1.51628904 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003756///protein disulfide isomerase activity+++GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity GO:0006457///protein folding+++GO:0034976///response to endoplasmic reticulum stress 69192 69192 'Dhx16' mRNA 867 991 957 13.92 15.66 16.3 12.52 12.28 11.92 15.29333333 12.24 897 859 827 938.3333333 861 0.224357589 -0.137242558 03040///Spliceosome GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity "GO:0000398///mRNA splicing, via spliceosome" 69195 69195 'Tmem121' mRNA 97 128 50 3.55 4.61 1.94 1.53 2.35 2.34 3.366666667 2.073333333 48 72 71 91.66666667 63.66666667 0.180759056 -0.517811913 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69202 69202 'Ptms' mRNA 1958 1877 917 104.92 99.36 52.14 59.12 63.22 72.65 85.47333333 64.99666667 1266 1320 1504 1584 1363.333333 0.614342337 -0.211287753 GO:0005643///nuclear pore+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003723///RNA binding+++GO:0003746///translation elongation factor activity+++GO:0008270///zinc ion binding+++GO:0043022///ribosome binding GO:0002376///immune system process+++GO:0006412///translation+++GO:0006414///translational elongation+++GO:0008150///biological_process+++GO:0015031///protein transport+++GO:0045901///positive regulation of translational elongation+++GO:0045905///positive regulation of translational termination+++GO:0051028///mRNA transport 69207 69207 'Srsf11' mRNA 3102 3070 2765 45.77 45.38 44.25 47.89 47.02 47.47 45.13333333 47.46 3557 3298 3459 2979 3438 0.001659486 0.196167994 GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding GO:0008150///biological_process+++GO:0008380///RNA splicing 69215 69215 'Sat2' mRNA 570 606 592 36.1 37.32 39.96 28.86 33.05 31.78 37.79333333 31.23 516 580 553 589.3333333 549.6666667 0.425184809 -0.111857775 00330///Arginine and proline metabolism+++04216///Ferroptosis GO:0005737///cytoplasm "GO:0004145///diamine N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019809///spermidine binding+++GO:0042802///identical protein binding" GO:0006596///polyamine biosynthetic process+++GO:0008215///spermine metabolic process+++GO:0008216///spermidine metabolic process+++GO:0032918///spermidine acetylation+++GO:0032919///spermine acetylation+++GO:0032920///putrescine acetylation+++GO:0046204///nor-spermidine metabolic process 69216 69216 'Svbp' mRNA 742 799 642 71.48 76.47 65.66 81.05 80.04 75.78 71.20333333 78.95666667 962 926 869 727.6666667 919 0.001250135 0.328042466 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0045177///apical part of cell GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0006508///proteolysis+++GO:0009306///protein secretion+++GO:0010596///negative regulation of endothelial cell migration+++GO:0031397///negative regulation of protein ubiquitination+++GO:0061564///axon development+++GO:1905048///regulation of metallopeptidase activity 69217 69217 'Plekha4' mRNA 1586 1582 1184 31.58 31.07 25.06 19.93 19.18 19.88 29.23666667 19.66333333 1135 1059 1106 1450.666667 1100 3.40E-05 -0.405614834 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0042802///identical protein binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway" 69219 69219 'Ddah1' mRNA 1456 1456 1521 21.18 20.94 23.74 18.85 17.78 19.93 21.95333333 18.85333333 1472 1380 1531 1477.666667 1461 0.802571526 -0.03021544 GO:0005739///mitochondrion GO:0008270///zinc ion binding+++GO:0016403///dimethylargininase activity+++GO:0016597///amino acid binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000052///citrulline metabolic process+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0006525///arginine metabolic process+++GO:0006527///arginine catabolic process+++GO:0006809///nitric oxide biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0017014///protein nitrosylation+++GO:0043116///negative regulation of vascular permeability+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0045766///positive regulation of angiogenesis+++GO:1900038///negative regulation of cellular response to hypoxia 69225 69225 'Naxd' mRNA 2247 2249 2155 102.53 101.64 104.69 92.53 87.69 87.53 102.9533333 89.25 2336 2162 2142 2217 2213.333333 0.868082289 -0.014605618 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0047453///ATP-dependent NAD(P)H-hydrate dehydratase activity+++GO:0052855///ADP-dependent NAD(P)H-hydrate dehydratase activity GO:0046496///nicotinamide nucleotide metabolic process+++GO:0110051///metabolite repair 69226 69226 'Snx24' mRNA 470.62 515.95 475.83 12.68 13.73 13.37 10.74 12.53 12.52 13.26 11.93 458.98 529.01 519.97 487.4666667 502.6533333 0.852594441 0.034766627 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0008150///biological_process+++GO:0015031///protein transport 69227 69227 'Selenot' mRNA 816 860 698 12.42 12.88 11.27 25.65 22.31 25.19 12.19 24.38333333 1939 1647 1844 791.3333333 1810 1.55E-42 1.183911761 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004791///thioredoxin-disulfide reductase activity+++GO:0016491///oxidoreductase activity GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0009749///response to glucose+++GO:0031016///pancreas development+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0042593///glucose homeostasis+++GO:0045454///cell redox homeostasis+++GO:0060124///positive regulation of growth hormone secretion+++GO:0098869///cellular oxidant detoxification 69228 69228 'Zfp746' mRNA 201 187 164 2.96 2.71 2.58 2.56 2.74 2.88 2.75 2.726666667 200 209 223 184 210.6666667 0.376851376 0.186667814 05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901216///positive regulation of neuron death" 69232 69232 'Qrich1' mRNA 1811 1941 1802 30.36 32.17 32.01 26.89 27.64 28.65 31.51333333 27.72666667 1876 1895 1948 1851.333333 1906.333333 0.753503025 0.031135202 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0003677///DNA binding "GO:0001822///kidney development+++GO:0006986///response to unfolded protein+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" 69234 69234 'Zfp688' mRNA 391 411 383 19.95 20.56 20.04 13.16 13.41 13.28 20.18333333 13.28333333 286 288 282 395 285.3333333 5.40E-04 -0.480371871 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 69237 69237 'Gtpbp4' mRNA 885 888 868 18.96 18.78 19.73 22.51 22.77 23.32 19.15666667 22.86666667 1210 1192 1212 880.3333333 1204.666667 3.32E-07 0.440619945 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002098///tRNA wobble uridine modification+++GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0008156///negative regulation of DNA replication+++GO:0008285///negative regulation of cell proliferation+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0030488///tRNA methylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033342///negative regulation of collagen binding+++GO:0042254///ribosome biogenesis+++GO:0050821///protein stabilization" 69239 69239 'Pdzph1' mRNA 751 747 816 9.69 9.48 11.17 1.32 1.62 1.04 10.11333333 1.326666667 118 141 90 771.3333333 116.3333333 2.43E-68 -2.743220535 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69241 69241 'Polr2d' mRNA 765 764 769 46.19 45.52 49.06 45.12 49.11 50.8 46.92333333 48.34333333 858 909 937 766 901.3333333 0.035651409 0.222885634 03020///RNA polymerase+++05016///Huntington disease "GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030880///RNA polymerase complex" GO:0000166///nucleotide binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0031369///translation initiation factor binding "GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0031990///mRNA export from nucleus in response to heat stress+++GO:0034402///recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex+++GO:0044237///cellular metabolic process+++GO:0045948///positive regulation of translational initiation" 69253 69253 'Hspb2' mRNA 289.86 290.65 307.61 32.86 33.35 37.86 39.44 39.7 36.73 34.69 38.62333333 379.7 371.49 329.49 296.04 360.2266667 0.087553476 0.270440367 05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005212///structural constituent of eye lens GO:0007525///somatic muscle development+++GO:0009408///response to heat 69256 69256 'Zfp397' mRNA 973.54 1131.62 861.3 8.87 10.4 8.33 6.4 6.37 6.03 9.2 6.266666667 802.32 767.73 738.23 988.82 769.4266667 3.67E-04 -0.369968694 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated" 69257 69257 'Elf2' mRNA 657 658 368 10.2 9.99 5.86 6.71 7.35 7.55 8.683333333 7.203333333 504 535 547 561 528.6666667 0.704909614 -0.084758819 04214///Apoptosis - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 69259 69259 'Kctd5' mRNA 592 519 328 13.44 11.6 7.9 7.29 10.9 10.14 10.98 9.443333333 369 539 497 479.6666667 468.3333333 0.894577642 -0.032143198 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0097602///cullin family protein binding GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051260///protein homooligomerization 69260 69260 'Ing2' mRNA 98 112 80 1.92 2.39 2 1.97 2.01 1.35 2.103333333 1.776666667 93 92 66 96.66666667 83.66666667 0.521164617 -0.215438077 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016580///Sin3 complex+++GO:0016602///CCAAT-binding factor complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0035064///methylated histone binding+++GO:0035091///phosphatidylinositol binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008285///negative regulation of cell proliferation+++GO:0030317///flagellated sperm motility+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0031065///positive regulation of histone deacetylation+++GO:0040008///regulation of growth+++GO:0042981///regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048133///male germ-line stem cell asymmetric division+++GO:0072520///seminiferous tubule development+++GO:2000772///regulation of cellular senescence+++GO:2001234///negative regulation of apoptotic signaling pathway" 69263 69263 'Rfc3' mRNA 228 277 270 11.5 14.01 14.41 19.79 17.08 19.72 13.30666667 18.86333333 442 376 428 258.3333333 415.3333333 8.33E-06 0.670743574 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005663///DNA replication factor C complex+++GO:0031390///Ctf18 RFC-like complex GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0008094///DNA-dependent ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0032508///DNA duplex unwinding+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 69269 69269 'Scnm1' mRNA 503 570 533 38.58 44.09 43.72 35.09 36.16 33.48 42.13 34.91 521 523 484 535.3333333 509.3333333 0.576232272 -0.083743522 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0019899///enzyme binding+++GO:0046872///metal ion binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 69270 69270 'Gins1' mRNA 14 31 31 0.81 1.78 1.9 7.01 6.23 6.49 1.496666667 6.576666667 138 120 124 25.33333333 127.3333333 2.00E-12 2.312768244 GO:0000811///GINS complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0071162///CMG complex GO:0005515///protein binding GO:0000727///double-strand break repair via break-induced replication+++GO:0001833///inner cell mass cell proliferation+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:1902983///DNA strand elongation involved in mitotic DNA replication 69274 69274 'Ctdspl' mRNA 428 422 416 4.65 4.44 4.91 4.01 3.74 4.03 4.666666667 3.926666667 413 379 411 422 401 0.593128933 -0.086076258 GO:0005634///nucleus GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 69276 69276 'Sec62' mRNA 3920 4142 4662 53.44 55.65 67.59 51.22 54.87 50.98 58.89333333 52.35666667 4303 4512 4160 4241.333333 4325 0.917322082 0.012221061 03060///Protein export+++04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane "GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0015031///protein transport+++GO:0031204///posttranslational protein targeting to membrane, translocation" 69277 69277 '3300002I08Rik' mRNA 966.74 917.72 800.96 15.84 14.36 14.02 8.65 7.67 9.79 14.74 8.703333333 752.93 601.79 807.74 895.14 720.82 0.00752206 -0.323106191 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 69281 69281 'Spata4' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005930///axoneme GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0051493///regulation of cytoskeleton organization 69282 69282 '1700001J03Rik' mRNA 43.42 45.02 40.11 0.77 0.89 1.27 0.18 0.24 0.5 0.976666667 0.306666667 12 9.01 19 42.85 13.33666667 7.45E-04 -1.688684219 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 69287 69287 'Odf3' mRNA 1 0 1 0.07 0 0.07 0.06 0 0 0.046666667 0.02 1 0 0 0.666666667 0.333333333 0.860258084 -0.929065017 GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 69288 69288 'Rhobtb1' mRNA 741 776 509 9.06 9.3 6.63 2.19 2.43 2.54 8.33 2.386666667 204 221 230 675.3333333 218.3333333 1.24E-27 -1.63168704 04120///Ubiquitin mediated proteolysis GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043652///engulfment of apoptotic cell 69296 69296 'Tmigd3' mRNA 2 1 0 0.06 0.03 0 0.18 0.36 0.18 0.03 0.24 3 6 3 1 4 0.290135305 2.013550357 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001609///G protein-coupled adenosine receptor activity+++GO:0004888///transmembrane signaling receptor activity GO:0008285///negative regulation of cell proliferation+++GO:0030336///negative regulation of cell migration+++GO:0032088///negative regulation of NF-kappaB transcription factor activity 69297 69297 'Lrrc46' mRNA 514 469 462 23.96 21.58 22.85 3.29 2.25 3.36 22.79666667 2.966666667 81 54 80 481.6666667 71.66666667 6.68E-55 -2.761821461 GO:0003674///molecular_function 69301 69301 'Tescl' mRNA 7 4 7 0.52 0.3 0.55 0 0.13 0.07 0.456666667 0.066666667 0 2 1 6 1 0.105764944 -2.595336132 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 69305 69305 'Dcps' mRNA 588 626 581 30.28 31.83 31.74 35.22 34.78 33.32 31.28333333 34.44 785 756 718 598.3333333 753 0.002477369 0.320100428 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000340///RNA 7-methylguanosine cap binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0050072///m7G(5')pppN diphosphatase activity "GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0036245///cellular response to menadione+++GO:0043069///negative regulation of programmed cell death+++GO:0045292///mRNA cis splicing, via spliceosome" 69306 69306 'Efcab9' mRNA 9 12 15 0.48 0.72 1.12 0.46 0.83 0.44 0.773333333 0.576666667 8 13 9 12 10 0.781420286 -0.278862159 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0061891///calcium ion sensor activity GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0048240///sperm capacitation 69307 69307 'Pxt1' mRNA 0 1 0 0 0.06 0 0.16 0.11 0.06 0.02 0.11 3 2 1 0.333333333 2 0.384483097 2.463445047 GO:0005634///nucleus+++GO:0005777///peroxisome GO:0005515///protein binding GO:0007283///spermatogenesis+++GO:0043065///positive regulation of apoptotic process 69309 69309 'Slc16a13' mRNA 406 400 378 8.21 8.06 8.32 9.78 8.82 9.27 8.196666667 9.29 541 479 491 394.6666667 503.6666667 0.006981235 0.339827003 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport 69310 69310 'Pacrg' mRNA 811 805 877 35.95 35.31 41.25 3.17 4.08 3.75 37.50333333 3.666666667 81 103 94 831 92.66666667 2.83E-100 -3.178247968 GO:0002177///manchette+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031982///vesicle+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0097225///sperm midpiece GO:0001664///G protein-coupled receptor binding+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0007286///spermatid development+++GO:0034613///cellular protein localization+++GO:0034620///cellular response to unfolded protein+++GO:0060548///negative regulation of cell death 69312 69312 'Ppp1r42' mRNA 46 48 41 1.69 1.82 1.49 0.15 0.26 0.19 1.666666667 0.2 5 8 7 45 6.666666667 4.33E-07 -2.762234744 GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0070840///dynein complex binding GO:0010921///regulation of phosphatase activity 69315 69315 '1700001L19Rik' mRNA 341 393 374 10.86 12.34 12.64 1.55 2.3 1.86 11.94666667 1.903333333 56 81 65 369.3333333 67.33333333 9.22E-37 -2.466123245 GO:0036064///ciliary basal body GO:0003674///molecular_function GO:0008150///biological_process 69325 69325 '1700012B09Rik' mRNA 0 2 0 0 0.21 0 0 0.38 0 0.07 0.126666667 0 4 0 0.666666667 1.333333333 0.797199703 1.049563426 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0003674///molecular_function GO:0060271///cilium assembly 69327 69327 '1700007K13Rik' mRNA 386 426 134 32.65 35.72 12.03 1.55 3.79 4.21 26.8 3.183333333 21 50 55 315.3333333 42 6.73E-06 -2.889666191 GO:0005634///nucleus GO:0003674///molecular_function GO:0006974///cellular response to DNA damage stimulus+++GO:0007368///determination of left/right symmetry+++GO:0010468///regulation of gene expression+++GO:0071494///cellular response to UV-C 69329 69329 'Cfap206' mRNA 1204 1303 1250 30.4 32.55 33.61 2.17 2.8 2.2 32.18666667 2.39 99 125 99 1252.333333 107.6666667 9.59E-165 -3.55142989 GO:0001534///radial spoke+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097649///A axonemal microtubule GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007288///sperm axoneme assembly+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:1901317///regulation of flagellated sperm motility 69349 69349 '1700008O03Rik' mRNA 10 15 17 0.42 0.88 0.81 0.76 0.58 0.98 0.703333333 0.773333333 19 9 20 14 16 0.862092506 0.170751869 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69352 69352 'Necab1' mRNA 27.79 12.35 15.75 0.31 0.13 0.19 0.31 0.07 0.17 0.21 0.183333333 32.54 7.17 16.85 18.63 18.85333333 0.998591786 0.005521666 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0001835///blastocyst hatching+++GO:0042984///regulation of amyloid precursor protein biosynthetic process 69354 69354 'Slc38a4' mRNA 15 13 24 0.21 0.18 0.35 0.24 0.16 0.12 0.246666667 0.173333333 20 13 10 17.33333333 14.33333333 0.726270277 -0.303435927 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport 69358 69358 'Lrrc51' mRNA 688 722 652 48.42 50.84 49.19 19.44 19.42 17.52 49.48333333 18.79333333 321 308 289 687.3333333 306 1.14E-24 -1.178457124 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 69364 69364 '1700012P22Rik' mRNA 711 699 630 49.06 48.12 46.61 3.59 4.43 4.06 47.93 4.026666667 59 71 63 680 64.33333333 3.73E-102 -3.411308985 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69367 69367 'Glrx2' mRNA 856.29 950.19 888.94 24.07 26.79 24.59 28.34 31.15 26.53 25.15 28.67333333 800.81 805.84 765.5 898.4733333 790.7166667 0.059317297 -0.196575176 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle "GO:0015035///protein disulfide oxidoreductase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0097573///glutathione oxidoreductase activity" GO:0010033///response to organic substance+++GO:0042542///response to hydrogen peroxide 69368 69368 'Wdfy1' mRNA 2778.63 2870.08 2734.01 34.25 36.69 36.06 31.1 32.03 27.95 35.66666667 30.36 2707.82 2648.14 2595.49 2794.24 2650.483333 0.226245923 -0.08817683 GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway 69371 69371 'Smco2' mRNA 3 0 0 0.14 0 0 0 0 0 0.046666667 0 0 0 0 1 0 0.653555534 -2.427804616 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69372 69372 'Mocs3' mRNA 54 79 20 1.87 2.69 0.73 1.2 1.08 0.65 1.763333333 0.976666667 40 35 21 51 32 0.22173864 -0.664053561 04122///Sulfur relay system GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016783///sulfurtransferase activity+++GO:0042292///URM1 activating enzyme activity+++GO:0046872///metal ion binding+++GO:0061604///molybdopterin-synthase sulfurtransferase activity+++GO:0061605///molybdopterin-synthase adenylyltransferase activity GO:0002098///tRNA wobble uridine modification+++GO:0002143///tRNA wobble position uridine thiolation+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0008033///tRNA processing+++GO:0008152///metabolic process+++GO:0032447///protein urmylation+++GO:0034227///tRNA thio-modification 69376 69376 'Zpbp2' mRNA 3 11 5 0.14 0.43 0.19 0.2 0.08 0.08 0.253333333 0.12 5 2 2 6.333333333 3 0.437410748 -1.08737276 GO:0001669///acrosomal vesicle+++GO:0002199///zona pellucida receptor complex+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0044297///cell body GO:0003674///molecular_function GO:0001675///acrosome assembly+++GO:0002638///negative regulation of immunoglobulin production+++GO:0006665///sphingolipid metabolic process+++GO:0007339///binding of sperm to zona pellucida+++GO:0032922///circadian regulation of gene expression+++GO:0046466///membrane lipid catabolic process 69379 69379 'C8g' mRNA 117 131 117 7.89 8.81 8.49 7.18 7.01 6.29 8.396666667 6.826666667 124 119 103 121.6666667 115.3333333 0.775375801 -0.0884845 04610///Complement and coagulation cascades+++05020///Prion disease+++05146///Amoebiasis+++05171///Coronavirus disease - COVID-19+++05322///Systemic lupus erythematosus GO:0005576///extracellular region+++GO:0005579///membrane attack complex+++GO:0005615///extracellular space GO:0001848///complement binding+++GO:0019841///retinol binding+++GO:0044877///protein-containing complex binding "GO:0002376///immune system process+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0019835///cytolysis+++GO:0045087///innate immune response" 69380 69380 '1700013G24Rik' mRNA 1 1 0 0.06 0.06 0 0 0 0 0.04 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69384 69384 'Tmem89' mRNA 1 0 0 0.15 0 0 0 0 0 0.05 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69386 69386 'H4c8' mRNA 82.08 60.31 90.69 17.7 13.07 20.77 23.43 28.03 21.9 17.18 24.45333333 123.1 142.58 110.49 77.69333333 125.39 0.016719661 0.675806046 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 69387 69387 'Dnajb13' mRNA 722 700 716 39.46 37.77 41.19 3.81 4.42 4.29 39.47333333 4.173333333 79 88 88 712.6666667 85 4.74E-95 -3.080050809 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097224///sperm connecting piece GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0006457///protein folding+++GO:0030030///cell projection organization+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:1904158///axonemal central apparatus assembly 69398 69398 'Cdhr4' mRNA 16 25 22 0.35 0.54 0.52 0.63 0.53 0.75 0.47 0.636666667 33 27 38 21 32.66666667 0.249688993 0.624112287 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 69399 69399 '1700025G04Rik' mRNA 1053 1002 624 12.36 11.98 7.77 7.79 8.06 8.36 10.70333333 8.07 710 705 729 893 714.6666667 0.03094409 -0.322805154 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69408 69408 'Dnajc17' mRNA 316 255 295 20 15.96 19.81 11.71 12.29 11.37 18.59 11.79 212 217 198.97 288.6666667 209.3233333 0.006301583 -0.479556909 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901998///toxin transport 69428 69428 '1700016C15Rik' mRNA 4 7 5 0.37 0.65 0.55 0.27 0.37 0.09 0.523333333 0.243333333 3 4 1 5.333333333 2.666666667 0.499169571 -1.007805311 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69440 69440 'Dennd6b' mRNA 790 751 754 9.08 8.48 9.17 3.32 2.71 3.23 8.91 3.086666667 333 265 313 765 303.6666667 1.20E-29 -1.346621745 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0055037///recycling endosome GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 69441 69441 'Efcab15' mRNA 55 51 60 3.8 3.55 4.57 1.75 1.93 1.56 3.973333333 1.746666667 30 30 24 55.33333333 28 0.012277921 -0.998359947 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 69453 69453 'Prss56' mRNA 36 38 24 0.95 0.96 0.67 0.49 0.43 0.28 0.86 0.4 20 19 11 32.66666667 16.66666667 0.075479549 -0.975632877 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0006508///proteolysis+++GO:0007596///blood coagulation+++GO:0043010///camera-type eye development 69454 69454 'Clic3' mRNA 432 459 459 33.49 35.17 38.58 29.43 26.06 26.41 35.74666667 27.3 431 372 378 450 393.6666667 0.149002258 -0.207035547 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0034707///chloride channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity GO:0006749///glutathione metabolic process+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport 69456 69456 'Commd10' mRNA 1173 1341 1238 44.07 49.68 49.44 40.96 46.7 40.87 47.73 42.84333333 1258 1392 1220 1250.666667 1290 0.798581712 0.033765575 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 69457 69457 'Tmem45a2' mRNA 0 1 0 0 0.04 0 0 0.04 0.11 0.013333333 0.05 0 1 5 0.333333333 2 0.426535524 2.478588902 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69459 69459 'Ubl7' mRNA 1866 1800 1760 82.73 78.25 82.83 76.45 74.31 73.06 81.27 74.60666667 1978 1881 1835 1808.666667 1898 0.522545373 0.057439172 GO:0005829///cytosol GO:0031593///polyubiquitin modification-dependent protein binding GO:0006511///ubiquitin-dependent protein catabolic process 69462 69462 'Slurp2' mRNA 1 0 1 0.19 0 0.2 0 0 0 0.13 0 0 0 0 0.666666667 0 0.746936975 -1.892661915 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0030548///acetylcholine receptor regulator activity+++GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding GO:0043616///keratinocyte proliferation+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0099601///regulation of neurotransmitter receptor activity+++GO:2000272///negative regulation of signaling receptor activity 69470 69470 'Tmem127' mRNA 2529 2581 2149 28.96 28.82 26.15 34.99 27.97 32.15 27.97666667 31.70333333 3488 2736 3127 2419.666667 3117 1.90E-05 0.354801832 GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031267///small GTPase binding GO:0007032///endosome organization+++GO:0008285///negative regulation of cell proliferation+++GO:0032006///regulation of TOR signaling+++GO:0032007///negative regulation of TOR signaling 69478 69478 '2300009A05Rik' mRNA 566 550 559 72.49 70.15 75.99 23.02 21.37 29.83 72.87666667 24.74 205 185 256 558.3333333 215.3333333 1.85E-21 -1.387351503 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 69479 69479 '1700029J07Rik' mRNA 740 789 764 17.57 18.62 18.74 4.3 3.57 4.56 18.31 4.143333333 197 165 205 764.3333333 189 1.29E-56 -2.029002644 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0097731///9+0 non-motile cilium GO:0003674///molecular_function GO:0008150///biological_process 69480 69480 'Ttc9' mRNA 192 183 118 2.15 2.02 1.4 1.52 1.24 1.61 1.856666667 1.456666667 156 124 160 164.3333333 146.6666667 0.546517366 -0.168713519 GO:0060348///bone development 69481 69481 'Actl9' mRNA 1 2 2 0.04 0.09 0.09 0 0 0 0.073333333 0 0 0 0 1.666666667 0 0.324592415 -3.197419472 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex GO:0003674///molecular_function GO:0008150///biological_process 69482 69482 'Nup35' mRNA 1435 1462 1442 29.02 29.09 30.93 16.71 17.15 18 29.68 17.28666667 950 952 991 1446.333333 964.3333333 9.50E-13 -0.596963067 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005652///nuclear lamina+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0044613///nuclear pore central transport channel+++GO:0044615///nuclear pore nuclear basket GO:0003676///nucleic acid binding+++GO:0003697///single-stranded DNA binding+++GO:0005543///phospholipid binding+++GO:0017056///structural constituent of nuclear pore+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006999///nuclear pore organization+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:1990830///cellular response to leukemia inhibitory factor" 69487 69487 'Ndufaf5' mRNA 138 166 167 7.05 7.65 7.85 8.28 7.8 9.05 7.516666667 8.376666667 211 176 196 157 194.3333333 0.179155611 0.292683715 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane GO:0003674///molecular_function+++GO:0008168///methyltransferase activity+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity GO:0030961///peptidyl-arginine hydroxylation+++GO:0032259///methylation+++GO:0032981///mitochondrial respiratory chain complex I assembly 69496 69496 'Dydc1' mRNA 26 20.44 21.13 1.67 1.34 1.33 0.06 0.08 0.12 1.446666667 0.086666667 1 1 2 22.52333333 1.333333333 4.62E-05 -4.077020572 "GO:0000781///chromosome, telomeric region+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex" GO:0006348///chromatin silencing at telomere+++GO:0031509///telomeric heterochromatin assembly+++GO:0051568///histone H3-K4 methylation 69499 69499 'Tsr2' mRNA 1637.73 1727.48 1568.23 23.34 24.22 23.71 14.53 14.99 14.43 23.75666667 14.65 1173.3 1182.61 1128.66 1644.48 1161.523333 2.73E-11 -0.512517292 GO:0005634///nucleus GO:0003674///molecular_function "GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing" 69504 69504 'Zfp932' mRNA 866.41 893.58 904.08 15.38 14.94 17.24 11.22 10.76 11.79 15.85333333 11.25666667 679.53 635.72 702.19 888.0233333 672.48 5.35E-05 -0.414865585 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0030154///cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045668///negative regulation of osteoblast differentiation" 69511 69511 'Klk12' mRNA 1 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0030141///secretory granule GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 69519 69519 'Rwdd2a' mRNA 114 108 115 5.64 5.31 6.04 5.38 5.09 5.47 5.663333333 5.313333333 124 114 122 112.3333333 120 0.795872331 0.081626708 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69520 69520 'Lce3f' mRNA 0 1 0 0 0.12 0 0.43 0.77 1.21 0.04 0.803333333 4 7 11 0.333333333 7.333333333 0.014820918 4.34898653 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0008544///epidermis development+++GO:0031424///keratinization 69524 69524 'Esam' mRNA 706 704 615 21.87 21.49 20.21 30.86 28.52 27.6 21.19 28.99333333 1145 1033 991 675 1056.333333 2.25E-11 0.635564577 04514///Cell adhesion molecules+++04670///Leukocyte transendothelial migration GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0098632///cell-cell adhesion mediator activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0030833///regulation of actin filament polymerization+++GO:0034613///cellular protein localization+++GO:0070830///bicellular tight junction assembly+++GO:0098609///cell-cell adhesion+++GO:2000249///regulation of actin cytoskeleton reorganization 69527 69527 'Mrps9' mRNA 661 655 643 27.77 26.99 28.5 26.56 25.75 24.76 27.75333333 25.69 733 691 660 653 694.6666667 0.554711803 0.07679179 03010///Ribosome GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation 69528 69528 '1700030J22Rik' mRNA 346 363 270 6.26 6.36 5.09 1.4 1.39 1.64 5.903333333 1.476666667 93 88 105 326.3333333 95.33333333 3.15E-22 -1.781757684 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 69534 69534 'Avpi1' mRNA 433 471 491 28.54 30.7 34.34 35.13 38.05 37.36 31.19333333 36.84666667 611 645 628 465 628 6.79E-04 0.420186043 GO:0005575///cellular_component GO:0003674///molecular_function GO:0000187///activation of MAPK activity+++GO:0007049///cell cycle+++GO:0043410///positive regulation of MAPK cascade 69535 69535 'Ten1' mRNA 597 573 500.22 43.48 41.31 38.66 47.42 47.87 46.72 41.15 47.33666667 746 733.68 710 556.74 729.8933333 3.82E-04 0.38102459 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:1990879///CST complex" GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0010521///telomerase inhibitor activity+++GO:0042162///telomeric DNA binding GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity 69536 69536 'Hemk1' mRNA 455 495 469 13.33 13.6 14.31 11.98 9.74 12.09 13.74666667 11.27 455 395 485 473 445 0.52792142 -0.100651458 GO:0005739///mitochondrion GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0102559///protein-(glutamine-N5) methyltransferase activity GO:0006479///protein methylation+++GO:0008150///biological_process+++GO:0032259///methylation 69537 69537 'Dnase1l1' mRNA 464 499 468 19.4 20.33 20.11 36.67 34.38 37.78 19.94666667 36.27666667 1048 955 1018 477 1007 1.36E-27 1.065903814 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004530///deoxyribonuclease I activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity "GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006308///DNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis" 69538 69538 'Antxr1' mRNA 745 750 622 7.55 7.47 6.68 6.3 6.06 6.01 7.233333333 6.123333333 716 673 662 705.6666667 683.6666667 0.691791844 -0.054722715 04621///NOD-like receptor signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0031527///filopodium membrane+++GO:0042995///cell projection GO:0004888///transmembrane signaling receptor activity+++GO:0005518///collagen binding+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0001568///blood vessel development+++GO:0022414///reproductive process+++GO:0031532///actin cytoskeleton reorganization+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:1901202///negative regulation of extracellular matrix assembly+++GO:1901998///toxin transport+++GO:1905050///positive regulation of metallopeptidase activity 69539 69539 'Trnp1' mRNA 341 338 316 11.86 11.48 11.47 4.1 3.71 3.99 11.60333333 3.933333333 136 120 129 331.6666667 128.3333333 3.35E-17 -1.381498297 GO:0000791///euchromatin+++GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021696///cerebellar cortex morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0061351///neural precursor cell proliferation 69540 69540 'Klk10' mRNA 3 3 0 0.13 0.13 0 0.66 0.51 0.64 0.086666667 0.603333333 17 13 16 2 15.33333333 0.004196222 2.94203972 GO:0030141///secretory granule GO:0004252///serine-type endopeptidase activity GO:0006508///proteolysis 69543 69543 'Capns2' mRNA 9 10 11 0.56 0.62 0.73 0.22 0.39 0.68 0.636666667 0.43 4 7 12 10 7.666666667 0.727544503 -0.394035868 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006508///proteolysis 69544 69544 'Wdr5b' mRNA 192 193 185 6.21 6.15 6.34 5.34 4.52 4.59 6.233333333 4.816666667 190 157 158 190 168.3333333 0.395393992 -0.187752232 04934///Cushing syndrome GO:0048188///Set1C/COMPASS complex GO:0042393///histone binding GO:0051568///histone H3-K4 methylation 69546 69546 'Mapk1ip1' mRNA 646 651 656 25.03 24.91 27.05 15.27 15.9 15.3 25.66333333 15.49 450 458 439 651 449 1.36E-06 -0.548457237 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0042802///identical protein binding GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0051321///meiotic cell cycle 69547 69547 'Nkpd1' mRNA 24 14 21 0.47 0.28 0.44 0.73 0.97 0.86 0.396666667 0.853333333 43 56 48 19.66666667 49 0.003907222 1.304313535 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69549 69549 '2310009B15Rik' mRNA 123 108 93 16.89 14.78 13.56 12.65 11.9 13.63 15.07666667 12.72666667 105 96 109 108 103.3333333 0.834897407 -0.072569112 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69550 69550 'Bst2' mRNA 1911 1988 1562 160.59 165.58 139.3 458.17 458.66 444.04 155.1566667 453.6233333 6241 6084 5840 1820.333333 6055 7.73E-145 1.726216657 05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft GO:0008191///metalloendopeptidase inhibitor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0002376///immune system process+++GO:0002737///negative regulation of plasmacytoid dendritic cell cytokine production+++GO:0009615///response to virus+++GO:0010951///negative regulation of endopeptidase activity+++GO:0030308///negative regulation of cell growth+++GO:0030336///negative regulation of cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:1901253///negative regulation of intracellular transport of viral material 69551 69551 '2310022B05Rik' mRNA 1156 1119 343 19.08 18.17 6 4.89 6.92 6.35 14.41666667 6.053333333 341 471 429 872.6666667 413.6666667 0.064483978 -1.061530731 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 69553 69553 'Ripor3' mRNA 3 5 2 0.05 0.08 0.03 0.46 0.49 0.4 0.053333333 0.45 35 37 30 3.333333333 34 2.01E-06 3.345771673 GO:0003674///molecular_function GO:0008150///biological_process 69554 69554 'Klhdc2' mRNA 1237 1409 672 36.3 40.74 20.92 16.08 21.1 20.05 32.65333333 19.07666667 630 807 760 1106 732.3333333 0.087973066 -0.588374769 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0031965///nuclear membrane "GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 69556 69556 'Bod1' mRNA 198 149 165 8.43 6.26 7.46 7.57 6.24 7.63 7.383333333 7.146666667 204 164 199 170.6666667 189 0.59882145 0.133642251 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule" GO:0004864///protein phosphatase inhibitor activity+++GO:0051721///protein phosphatase 2A binding "GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0051301///cell division+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0071962///mitotic sister chromatid cohesion, centromeric+++GO:1990758///mitotic sister chromatid biorientation" 69562 69562 'Cdk13' mRNA 537.08 582.7 466 3.38 3.44 2.87 2.56 2.47 2.82 3.23 2.616666667 452.99 418.95 480.13 528.5933333 450.69 0.068756765 -0.240130377 GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0002945///cyclin K-CDK13 complex+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0016607///nuclear speck+++GO:0019908///nuclear cyclin-dependent protein kinase holoenzyme complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030332///cyclin binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0008380///RNA splicing+++GO:0016310///phosphorylation+++GO:0030097///hemopoiesis+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0051726///regulation of cell cycle+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:2000737///negative regulation of stem cell differentiation" 69563 69563 'Mrln' mRNA 36 30 31 7.42 6.21 7.13 3.64 2.9 3.29 6.92 3.276666667 20 15 17 32.33333333 17.33333333 0.082572208 -0.912995187 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding GO:0009611///response to wounding+++GO:0043086///negative regulation of catalytic activity+++GO:1901877///negative regulation of calcium ion binding+++GO:1901895///negative regulation of calcium-transporting ATPase activity+++GO:1902081///negative regulation of calcium ion import into sarcoplasmic reticulum 69564 69564 'Nmrk2' mRNA 3.88 4.22 7.54 0.12 0.13 0.25 0.03 0.17 0.06 0.166666667 0.086666667 1.02 6.18 2.02 5.213333333 3.073333333 0.700563941 -0.654048778 00760///Nicotinate and nicotinamide metabolism GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0050262///ribosylnicotinamide kinase activity+++GO:0061769///ribosylnicotinate kinase activity GO:0009435///NAD biosynthetic process+++GO:0016310///phosphorylation+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0045662///negative regulation of myoblast differentiation 69568 69568 'Vkorc1l1' mRNA 347.88 325.57 337.92 3.78 3.48 3.9 3.47 3.34 3.88 3.72 3.563333333 364.89 344.64 398.4 337.1233333 369.31 0.48450236 0.119739239 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity+++GO:0047057///vitamin-K-epoxide reductase (warfarin-sensitive) activity+++GO:0048038///quinone binding GO:0017187///peptidyl-glutamic acid carboxylation+++GO:0034599///cellular response to oxidative stress+++GO:0042373///vitamin K metabolic process 69572 69572 'Mfsd3' mRNA 230.91 253.83 238.86 6.01 6.51 6.6 8.19 8.32 8.07 6.373333333 8.193333333 362 358.75 344.94 241.2 355.23 2.17E-04 0.54966209 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015295///solute:proton symporter activity+++GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 69573 69573 'Hilpda' mRNA 410 420 432 26.71 27.06 29.86 34.1 34.93 29.17 27.87666667 32.73333333 600 599 496 420.6666667 565 0.001866176 0.412111126 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005811///lipid droplet+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule GO:0005102///signaling receptor binding GO:0001819///positive regulation of cytokine production+++GO:0008284///positive regulation of cell proliferation+++GO:0010884///positive regulation of lipid storage+++GO:0035425///autocrine signaling+++GO:0071456///cellular response to hypoxia 69574 69574 'Cmbl' mRNA 587 537 531 31.12 28.18 29.17 31.74 29.75 30.73 29.49 30.74 686 632 629 551.6666667 649 0.057312322 0.222335474 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0008150///biological_process 69576 69576 'Smco1' mRNA 47.33 45.6 47.75 2.02 1.92 2.17 0.87 2.05 1.33 2.036666667 1.416666667 23.45 53.74 34.46 46.89333333 37.21666667 0.498653683 -0.344336709 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69577 69577 'Fastkd3' mRNA 221 307 250 4.95 7.18 6.16 6.36 6.31 6.05 6.096666667 6.24 311 300 300 259.3333333 303.6666667 0.241634618 0.217170764 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0003723///RNA binding GO:0000963///mitochondrial RNA processing+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0070131///positive regulation of mitochondrial translation 69581 69581 'Rhou' mRNA 800 833 610 12.95 13.27 10.48 12.69 11.64 12.73 12.23333333 12.35333333 902 808 876 747.6666667 862 0.096375543 0.198437621 GO:0000139///Golgi membrane+++GO:0002102///podosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0032488///Cdc42 protein signal transduction 69582 69582 'Plekhm2' mRNA 562 603 450 7.31 7.72 6.21 7.49 6.56 8.26 7.08 7.436666667 662 567 708 538.3333333 645.6666667 0.058574394 0.254732261 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0044754///autolysosome GO:0019894///kinesin binding GO:0007030///Golgi organization+++GO:0032418///lysosome localization+++GO:0032880///regulation of protein localization+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0061909///autophagosome-lysosome fusion+++GO:1902774///late endosome to lysosome transport+++GO:1903527///positive regulation of membrane tubulation 69583 69583 'Tnfsf13' mRNA 2701.7 2786.39 2616 93.68 95.24 96.22 95.82 89.41 95.03 95.04666667 93.42 3175.63 2892.16 3047.66 2701.363333 3038.483333 0.017935472 0.157594298 04060///Cytokine-cytokine receptor interaction+++04672///Intestinal immune network for IgA production+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0048018///receptor ligand activity GO:0002376///immune system process+++GO:0002426///immunoglobulin production in mucosal tissue+++GO:0002636///positive regulation of germinal center formation+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0016064///immunoglobulin mediated immune response+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0050776///regulation of immune response 69585 69585 'Hjv' mRNA 3 5 3 0.08 0.14 0.09 0.1 0.08 0.1 0.103333333 0.093333333 4 3 4 3.666666667 3.666666667 0.998591786 -0.007167327 04350///TGF-beta signaling pathway GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0031225///anchored component of membrane+++GO:0070724///BMP receptor complex+++GO:0098797///plasma membrane protein complex+++GO:1990712///HFE-transferrin receptor complex GO:0005102///signaling receptor binding+++GO:0015026///coreceptor activity+++GO:0036122///BMP binding+++GO:0098821///BMP receptor activity+++GO:1990459///transferrin receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006879///cellular iron ion homeostasis+++GO:0016540///protein autoprocessing+++GO:0030509///BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032924///activin receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055072///iron ion homeostasis+++GO:0071773///cellular response to BMP stimulus 69587 69587 'Pcgf3' mRNA 733 735 550 7.9 8.55 5.23 6.1 6.32 8.12 7.226666667 6.846666667 666 659 677 672.6666667 667.3333333 0.906180217 -0.017708062 04550///Signaling pathways regulating pluripotency of stem cells GO:0000805///X chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0060819///inactivation of X chromosome by genetic imprinting 69590 69590 'Gpx8' mRNA 1035 1185 1102 64.09 72.58 72.25 96.39 97.14 93.47 69.64 95.66666667 1781 1750 1668 1107.333333 1733 2.45E-14 0.634148263 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity GO:0006979///response to oxidative stress+++GO:0098869///cellular oxidant detoxification 69592 69592 'Odam' mRNA 0 1 0 0 0.04 0 0.04 0.14 0.22 0.013333333 0.133333333 1 4 6 0.333333333 3.666666667 0.136705667 3.352951768 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071944///cell periphery+++GO:0072686///mitotic spindle+++GO:0099512///supramolecular fiber GO:0003674///molecular_function GO:0001934///positive regulation of protein phosphorylation+++GO:0006954///inflammatory response+++GO:0009611///response to wounding+++GO:0010628///positive regulation of gene expression+++GO:0031214///biomineral tissue development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043547///positive regulation of GTPase activity+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing 69596 69596 'Ap5s1' mRNA 577 531 583 21.16 19.19 22.68 23.6 21.06 21.79 21.01 22.15 740 643 660 563.6666667 681 0.034261447 0.257869674 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0031902///late endosome membrane GO:0003674///molecular_function GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0015031///protein transport+++GO:0016197///endosomal transport 69597 69597 'Afg3l2' mRNA 2114 2096 2143 29.91 29.52 32.36 24.4 24.26 22.53 30.59666667 23.73 1954 1908 1755 2117.666667 1872.333333 0.019923984 -0.190986261 05017///Spinocerebellar ataxia GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005745///m-AAA complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007005///mitochondrion organization+++GO:0007409///axonogenesis+++GO:0007528///neuromuscular junction development+++GO:0008053///mitochondrial fusion+++GO:0016485///protein processing+++GO:0016540///protein autoprocessing+++GO:0021675///nerve development+++GO:0033619///membrane protein proteolysis+++GO:0034982///mitochondrial protein processing+++GO:0036444///calcium import into the mitochondrion+++GO:0040014///regulation of multicellular organism growth+++GO:0042407///cristae formation+++GO:0042552///myelination+++GO:0048747///muscle fiber development+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0055001///muscle cell development+++GO:0060013///righting reflex+++GO:0065003///protein-containing complex assembly 69601 69601 'Dab2ip' mRNA 2011 1955 1692 17.82 17.03 15.93 11.61 11.01 10.71 16.92666667 11.11 1520 1392 1343 1886 1418.333333 8.45E-08 -0.420959409 04210///Apoptosis+++04668///TNF signaling pathway GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044300///cerebellar mossy fiber+++GO:0044301///climbing fiber+++GO:1990032///parallel fiber+++GO:1990597///AIP1-IRE1 complex GO:0005096///GTPase activator activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035591///signaling adaptor activity+++GO:0035662///Toll-like receptor 4 binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0071889///14-3-3 protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000185///activation of MAPKKK activity+++GO:0001525///angiogenesis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006986///response to unfolded protein+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007252///I-kappaB phosphorylation+++GO:0007257///activation of JUN kinase activity+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010596///negative regulation of endothelial cell migration+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010976///positive regulation of neuron projection development+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016525///negative regulation of angiogenesis+++GO:0021814///cell motility involved in cerebral cortex radial glia guided migration+++GO:0021819///layer formation in cerebral cortex+++GO:0030308///negative regulation of cell growth+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0031334///positive regulation of protein complex assembly+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0035148///tube formation+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0038026///reelin-mediated signaling pathway+++GO:0040008///regulation of growth+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043087///regulation of GTPase activity+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043254///regulation of protein complex assembly+++GO:0043407///negative regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0044257///cellular protein catabolic process+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046330///positive regulation of JNK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0048812///neuron projection morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051726///regulation of cell cycle+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090129///positive regulation of synapse maturation+++GO:1900006///positive regulation of dendrite development+++GO:1900744///regulation of p38MAPK cascade+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1903363///negative regulation of cellular protein catabolic process+++GO:2001224///positive regulation of neuron migration+++GO:2001235///positive regulation of apoptotic signaling pathway" 69602 69602 'Otop3' mRNA 0 0 1 0 0 0.04 0 0 0.03 0.013333333 0.01 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015252///proton channel activity GO:0006811///ion transport+++GO:1902600///proton transmembrane transport 69605 69605 'Lnpk' mRNA 584 547 543 3.51 3.22 3.46 2.94 2.45 2.4 3.396666667 2.596666667 566 459 445 558 490 0.144650729 -0.201206802 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098826///endoplasmic reticulum tubular network membrane GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007029///endoplasmic reticulum organization+++GO:0007275///multicellular organism development+++GO:0007596///blood coagulation+++GO:0032330///regulation of chondrocyte differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071788///endoplasmic reticulum tubular network maintenance+++GO:1903373///positive regulation of endoplasmic reticulum tubular network organization 69606 69606 'Mtfmt' mRNA 241.9 305.01 269.51 6.73 8.36 7.95 7.63 6.08 6.8 7.68 6.836666667 315.29 245.33 272.11 272.14 277.5766667 0.942459776 0.016368191 00670///One carbon pool by folate+++00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion "GO:0004479///methionyl-tRNA formyltransferase activity+++GO:0016740///transferase activity+++GO:0016742///hydroxymethyl-, formyl- and related transferase activity" GO:0006412///translation+++GO:0006413///translational initiation+++GO:0009058///biosynthetic process+++GO:0071951///conversion of methionyl-tRNA to N-formyl-methionyl-tRNA 69608 69608 'Sec24d' mRNA 1061.6 1168 1094 13.49 14.58 14.64 18.29 19.5 18.24 14.23666667 18.67666667 1561 1658 1516 1107.866667 1578.333333 5.70E-09 0.499667736 04141///Protein processing in endoplasmic reticulum+++05130///Pathogenic Escherichia coli infection GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0000149///SNARE binding+++GO:0008270///zinc ion binding GO:0001701///in utero embryonic development+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0090110///cargo loading into COPII-coated vesicle 69612 69612 'Kansl2' mRNA 1490 1479 737 28.35 27.03 15.25 15.08 24.75 20.66 23.54333333 20.16333333 874 1462 1191 1235.333333 1175.666667 0.899697113 -0.062521499 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0044545///NSL complex GO:0006325///chromatin organization+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation 69617 69617 'Pitrm1' mRNA 724.42 830.96 763.84 11.42 12.91 12.69 10.9 10.97 11.77 12.34 11.21333333 794.58 786.54 832.93 773.0733333 804.6833333 0.739687458 0.046475822 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0016485///protein processing 69627 69627 'Fam89a' mRNA 0 0 1.61 0 0 0.07 0.37 0.13 0 0.023333333 0.166666667 9.77 3.43 0.08 0.536666667 4.426666667 0.147139514 3.452334575 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69632 69632 'Arhgef12' mRNA 1423.41 1411.37 1352.43 6.12 6.05 6.2 5.27 4.78 5.38 6.123333333 5.143333333 1373.52 1233.35 1337.72 1395.736667 1314.863333 0.284294411 -0.09845514 04270///Vascular smooth muscle contraction+++04360///Axon guidance+++04361///Axon regeneration+++04611///Platelet activation+++04625///C-type lectin receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05135///Yersinia infection+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0008217///regulation of blood pressure+++GO:0010259///multicellular organism aging+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 69634 69634 'Clybl' mRNA 357 426 405 16.7 19.96 20.03 16 13.02 15 18.89666667 14.67333333 387 314 363 396 354.6666667 0.296028432 -0.173212062 GO:0005739///mitochondrion GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004474///malate synthase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0047777///(3S)-citramalyl-CoA lyase activity GO:0070207///protein homotrimerization+++GO:0106064///regulation of cobalamin metabolic process+++GO:0106121///positive regulation of cobalamin metabolic process 69635 69635 'Dapk1' mRNA 1158 1186 789 10.82 10.7 7.66 3.58 4.29 3.87 9.726666667 3.913333333 449 519 468 1044.333333 478.6666667 5.00E-18 -1.127620438 04140///Autophagy - animal+++05200///Pathways in cancer+++05219///Bladder cancer GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0042802///identical protein binding GO:0002357///defense response to tumor cell+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0010508///positive regulation of autophagy+++GO:0016310///phosphorylation+++GO:0017148///negative regulation of translation+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0071346///cellular response to interferon-gamma+++GO:0071447///cellular response to hydroperoxide+++GO:0097190///apoptotic signaling pathway+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000310///regulation of NMDA receptor activity 69638 69638 'Enho' mRNA 2126 2092 1925 103.94 100.98 99.85 49.11 48.6 49.99 101.59 49.23333333 1153 1113 1135 2047.666667 1133.666667 1.21E-33 -0.863665658 GO:0005576///extracellular region+++GO:0005886///plasma membrane GO:0005179///hormone activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0045747///positive regulation of Notch signaling pathway 69639 69639 'Exosc8' mRNA 243 276 302 11.63 13.04 15.33 16.75 20.81 19.09 13.33333333 18.88333333 402 487 443 273.6666667 444 1.44E-05 0.68459542 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0003723///RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042802///identical protein binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0006401///RNA catabolic process+++GO:0016075///rRNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034473///U1 snRNA 3'-end processing+++GO:0034475///U4 snRNA 3'-end processing+++GO:0034476///U5 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0071028///nuclear mRNA surveillance+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process" 69640 69640 'Fam83g' mRNA 140.97 162 166.97 1.59 1.78 1.99 1.61 1.52 1.78 1.786666667 1.636666667 166 153 177 156.6466667 165.3333333 0.805445604 0.069599642 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019901///protein kinase binding GO:0007165///signal transduction+++GO:0030509///BMP signaling pathway 69641 69641 'Wdr20' mRNA 656.54 598.31 640.79 10.46 9.93 10.85 9.46 8.8 8.5 10.41333333 8.92 579.91 549.34 504.42 631.88 544.5566667 0.067459795 -0.228545625 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69642 69642 'Mlip' mRNA 469 518 507 21.34 23.07 24.42 22.41 24.07 22.4 22.94333333 22.96 562 580 553 498 565 0.199196612 0.169742139 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016605///PML body+++GO:0031981///nuclear lumen+++GO:0042383///sarcolemma GO:0003714///transcription corepressor activity+++GO:0005521///lamin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress 69654 69654 'Dctn2' mRNA 3210 3101 3032 98.48 94.08 98.96 100.61 99.28 100.42 97.17333333 100.1033333 3750 3643 3627 3114.333333 3673.333333 2.81E-04 0.226257551 04962///Vasopressin-regulated water reabsorption+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0000776///kinetochore+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005869///dynactin complex+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030286///dynein complex+++GO:0030426///growth cone+++GO:0031982///vesicle GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030507///spectrin binding+++GO:0042802///identical protein binding GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0007052///mitotic spindle organization+++GO:0007080///mitotic metaphase plate congression+++GO:0032402///melanosome transport+++GO:0071539///protein localization to centrosome 69655 69655 'Cd164l2' mRNA 2857 2904 2908 185.9 186.9 200.78 25.54 25.1 25.02 191.1933333 25.22 450 431 426 2889.666667 435.6666667 1.26E-247 -2.742763585 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0008150///biological_process 69656 69656 'Pir' mRNA 146 108 109 5.99 4.29 4.62 4.76 4.36 4.5 4.966666667 4.54 126 125 117 121 122.6666667 0.981123824 0.009523499 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003712///transcription coregulator activity+++GO:0008127///quercetin 2,3-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0030099///myeloid cell differentiation+++GO:0030224///monocyte differentiation 69660 69660 'Tmbim1' mRNA 7309 7393 7133 177.62 176.92 183.89 150.96 155.54 154.65 179.4766667 153.7166667 7144 7187 7085 7278.333333 7138.666667 0.565673726 -0.039679302 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005123///death receptor binding GO:0043086///negative regulation of catalytic activity+++GO:0050848///regulation of calcium-mediated signaling+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902045///negative regulation of Fas signaling pathway+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000504///positive regulation of blood vessel remodeling 69662 69662 '2310061I04Rik' mRNA 698 641 552 34.24 30.98 28.99 23.45 23.89 23.51 31.40333333 23.61666667 542 546 532 630.3333333 540 0.057218169 -0.231630141 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69663 69663 'Ddx51' mRNA 398 397 102 4.39 4.31 1.19 0.92 1.97 2.46 3.296666667 1.783333333 96 201 249 299 182 0.405642764 -0.694760494 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 69665 69665 'Upk3bl' mRNA 22 20 22 1.32 1.2 1.4 3.33 3.26 3.18 1.306666667 3.256666667 63 60 58 21.33333333 60.33333333 1.65E-04 1.486555671 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004601///peroxidase activity+++GO:0020037///heme binding GO:0006979///response to oxidative stress+++GO:0008150///biological_process+++GO:0098869///cellular oxidant detoxification 69666 69666 'Psmg4' mRNA 256 256 274 40.22 40.64 46.41 46.89 53.74 48.3 42.42333333 49.64333333 351 393 354 262 366 0.00239612 0.469534292 GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0008150///biological_process+++GO:0043248///proteasome assembly 69668 69668 'Ccdc115' mRNA 761 840 723 25.9 28.18 26.11 37.05 38.69 36.06 26.73 37.26666667 1250.94 1275 1177.91 774.6666667 1234.616667 1.56E-13 0.661890726 GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030137///COPI-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0042406///extrinsic component of endoplasmic reticulum membrane GO:0051082///unfolded protein binding GO:0006879///cellular iron ion homeostasis+++GO:0007042///lysosomal lumen acidification+++GO:0036295///cellular response to increased oxygen levels+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:1905146///lysosomal protein catabolic process 69671 69671 'Tmem52' mRNA 761 794 704 51.64 53.27 50.66 26.04 23.13 22.62 51.85666667 23.93 439 381 369 753 396.3333333 2.60E-17 -0.937278398 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69672 69672 'Txndc15' mRNA 2849 2963 2769 109.95 112.78 113.38 97.73 98.02 91.89 112.0366667 95.88 2909 2847 2646 2860.333333 2800.666667 0.624480294 -0.041978268 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060271///cilium assembly 69674 69674 'Mif4gd' mRNA 1588 1582 1571 68.4 67.31 71.82 49.84 48.93 49.51 69.17666667 49.42666667 1330 1269 1268 1580.333333 1289 1.14E-04 -0.306625576 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0008022///protein C-terminus binding+++GO:0008494///translation activator activity+++GO:0042802///identical protein binding GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation 69675 69675 'Pxdn' mRNA 77 63 89 0.61 0.48 0.74 1.24 1.36 1.29 0.61 1.296666667 182 192 183 76.33333333 185.6666667 4.90E-08 1.265790024 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0062023///collagen-containing extracellular matrix GO:0004601///peroxidase activity+++GO:0005201///extracellular matrix structural constituent+++GO:0016491///oxidoreductase activity+++GO:0019806///bromide peroxidase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0006979///response to oxidative stress+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification 69683 69683 'Emc10' mRNA 4442 4312 2340 136.11 129.6 75.73 74.19 112.49 104.63 113.8133333 97.10333333 2757 4079 3749 3698 3528.333333 0.88450994 -0.061438849 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0045766///positive regulation of angiogenesis+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:1900745///positive regulation of p38MAPK cascade 69684 69684 'Aarsd1' mRNA 1139 1175 1179 50.59 51.21 55.87 39.05 40.8 42.86 52.55666667 40.90333333 1008 1024 1076 1164.333333 1036 0.06310395 -0.180955731 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0002196///Ser-tRNA(Ala) hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0006419///alanyl-tRNA aminoacylation+++GO:0006450///regulation of translational fidelity+++GO:0043039///tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 69692 69692 'Hddc2' mRNA 469.33 493.48 445.9 37.89 39.06 38.97 38.05 41.61 40.43 38.64 40.03 536.81 557.39 530.8 469.57 541.6666667 0.12172113 0.195799786 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0002953///5'-deoxynucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 69693 69693 'Pof1b' mRNA 44 50 41 0.77 0.8 0.7 0.38 0.7 0.6 0.756666667 0.56 27 40 43 45 36.66666667 0.533819199 -0.301424353 GO:0005884///actin filament+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0003382///epithelial cell morphogenesis+++GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0070830///bicellular tight junction assembly 69694 69694 'Tatdn1' mRNA 358.56 394.71 344.86 8.93 9.98 9.28 9.68 9.09 11.02 9.396666667 9.93 427.43 399.48 473.16 366.0433333 433.3566667 0.105684911 0.234777381 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0004518///nuclease activity+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters+++GO:0046872///metal ion binding" GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 69697 69697 'Camsap3' mRNA 660 643 393 8.22 7.9 5.22 2.64 2.7 3.88 7.113333333 3.073333333 244 244 348 565.3333333 278.6666667 3.48E-08 -1.020916017 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005912///adherens junction+++GO:0005915///zonula adherens+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0036449///microtubule minus-end+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008017///microtubule binding+++GO:0030507///spectrin binding+++GO:0051011///microtubule minus-end binding+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0001701///in utero embryonic development+++GO:0003341///cilium movement+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010923///negative regulation of phosphatase activity+++GO:0030030///cell projection organization+++GO:0030334///regulation of cell migration+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0031113///regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0031175///neuron projection development+++GO:0033043///regulation of organelle organization+++GO:0034453///microtubule anchoring+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045218///zonula adherens maintenance+++GO:0051893///regulation of focal adhesion assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0090136///epithelial cell-cell adhesion+++GO:0098840///protein transport along microtubule+++GO:1903358///regulation of Golgi organization 69698 69698 'Slc52a3' mRNA 624 561 568 13.32 12.03 13.18 11.76 11.83 10.71 12.84333333 11.43333333 621 613 550 584.3333333 594.6666667 0.931938108 0.013247737 04977///Vitamin digestion and absorption GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0032217///riboflavin transmembrane transporter activity GO:0007605///sensory perception of sound+++GO:0032218///riboflavin transport+++GO:0034605///cellular response to heat 69700 69700 'Col22a1' mRNA 76.55 82.59 77.55 0.63 0.6 0.66 0.31 0.27 0.33 0.63 0.303333333 41.48 36.01 43.41 78.89666667 40.3 0.002611668 -0.981851092 04974///Protein digestion and absorption GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0030198///extracellular matrix organization 69702 69702 'Ndufaf1' mRNA 302 342 288 12.71 14.29 12.94 13.21 14.35 11.38 13.31333333 12.98 350 374 297 310.6666667 340.3333333 0.511478891 0.122205312 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol GO:0051082///unfolded protein binding "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0010257///NADH dehydrogenase complex assembly+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0051131///chaperone-mediated protein complex assembly" 69706 69706 'Lrr1' mRNA 0 3 0 0 0.12 0 1.95 1.4 1.17 0.04 1.506666667 57 40 33 1 43.33333333 7.45E-08 5.429511274 GO:0003674///molecular_function+++GO:0016853///isomerase activity 69707 69707 'Iqcg' mRNA 1265.83 1196.07 1222.77 17.65 16.16 17.78 2.09 2.12 1.93 17.19666667 2.046666667 177.61 172.71 159.05 1228.223333 169.79 2.13E-139 -2.870892712 GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0005516///calmodulin binding+++GO:0030544///Hsp70 protein binding GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0007288///sperm axoneme assembly+++GO:0030154///cell differentiation+++GO:0044782///cilium organization 69709 69709 'Ptrhd1' mRNA 243.38 258.84 281.22 3.26 3.41 4 4.69 4.89 4.24 3.556666667 4.606666667 403.01 410.14 352.93 261.1466667 388.6933333 3.02E-04 0.560496551 GO:0003674///molecular_function+++GO:0004045///aminoacyl-tRNA hydrolase activity+++GO:0016787///hydrolase activity GO:0008150///biological_process 69710 69710 'Arap1' mRNA 1506 1603 1448 15.5 16.32 16.08 22.77 21.71 20.04 15.96666667 21.50666667 2498 2338 2199 1519 2345 2.26E-17 0.615082905 04144///Endocytosis GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008134///transcription factor binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding" "GO:0001921///positive regulation of receptor recycling+++GO:0007165///signal transduction+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0043547///positive regulation of GTPase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051270///regulation of cellular component movement+++GO:0051491///positive regulation of filopodium assembly+++GO:0051497///negative regulation of stress fiber assembly+++GO:0060395///SMAD protein signal transduction" 69713 69713 'Pin4' mRNA 371 382 421 68.93 71.6 83.64 82.14 83.99 81.25 74.72333333 82.46 500 494 476 391.3333333 490 0.02541809 0.309616402 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030684///preribosome GO:0003677///DNA binding+++GO:0003681///bent DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0006364///rRNA processing 69714 69714 'Tfpt' mRNA 367 353 360 19.78 18.81 20.63 18.58 18.64 19.47 19.74 18.89666667 395 387 400 360 394 0.460711833 0.1177594 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0031011///Ino80 complex GO:0003677///DNA binding+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0097190///apoptotic signaling pathway 69716 69716 'Trip13' mRNA 24 15 20 0.6 0.37 0.53 2.72 3.51 2.85 0.5 3.026666667 126 159 128 19.66666667 137.6666667 6.24E-18 2.796653484 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding GO:0001556///oocyte maturation+++GO:0006302///double-strand break repair+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle+++GO:0051598///meiotic recombination checkpoint 69717 69717 'Gm10499' mRNA 151.72 189.88 165.37 6.79 8.66 7.8 43.87 44.22 45.22 7.75 44.43666667 1056.85 1046.81 1064.62 168.99 1056.093333 4.75E-109 2.637476819 04144///Endocytosis+++04145///Phagosome+++04218///Cellular senescence+++04514///Cell adhesion molecules+++04612///Antigen processing and presentation+++04940///Type I diabetes mellitus+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05332///Graft-versus-host disease+++05416///Viral myocarditis 69718 69718 'Ipmk' mRNA 190 207 102 1.86 2.24 1.14 1.66 2.82 2.71 1.746666667 2.396666667 175 283 290 166.3333333 249.3333333 0.027214856 0.590100351 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0000823///inositol-1,4,5-trisphosphate 6-kinase activity+++GO:0000824///inositol tetrakisphosphate 3-kinase activity+++GO:0000825///inositol tetrakisphosphate 6-kinase activity+++GO:0005524///ATP binding+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0047326///inositol tetrakisphosphate 5-kinase activity+++GO:0051765///inositol tetrakisphosphate kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity+++GO:0097243///flavonoid binding+++GO:0102732///myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity" GO:0001841///neural tube formation+++GO:0006629///lipid metabolic process+++GO:0016310///phosphorylation+++GO:0032957///inositol trisphosphate metabolic process+++GO:0032958///inositol phosphate biosynthetic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0070266///necroptotic process 69719 69719 'Cad' mRNA 616 658 601 4.53 4.77 4.68 4.54 3.94 3.41 4.66 3.963333333 709 602 517 625 609.3333333 0.770694538 -0.049470981 "00240///Pyrimidine metabolism+++00250///Alanine, aspartate and glutamate metabolism+++01240///Biosynthesis of cofactors" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton "GO:0000166///nucleotide binding+++GO:0002134///UTP binding+++GO:0003824///catalytic activity+++GO:0004070///aspartate carbamoyltransferase activity+++GO:0004088///carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity+++GO:0004151///dihydroorotase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0016743///carboxyl- or carbamoyltransferase activity+++GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0016812///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides+++GO:0016874///ligase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0001889///liver development+++GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006225///UDP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006541///glutamine metabolic process+++GO:0006807///nitrogen compound metabolic process+++GO:0007507///heart development+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0014075///response to amine+++GO:0017144///drug metabolic process+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0019240///citrulline biosynthetic process+++GO:0031000///response to caffeine+++GO:0031100///animal organ regeneration+++GO:0032868///response to insulin+++GO:0033574///response to testosterone+++GO:0035690///cellular response to drug+++GO:0042594///response to starvation+++GO:0044205///'de novo' UMP biosynthetic process+++GO:0046777///protein autophosphorylation+++GO:0051414///response to cortisol+++GO:0071364///cellular response to epidermal growth factor stimulus 69721 69721 'Nkiras1' mRNA 550.75 559.66 556.71 23.81 23.95 26.49 17.52 18.49 19.36 24.75 18.45666667 463.63 479.52 458.17 555.7066667 467.1066667 0.033951257 -0.262200716 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0032794///GTPase activating protein binding GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0008150///biological_process+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0032484///Ral protein signal transduction+++GO:0043129///surfactant homeostasis+++GO:0048286///lung alveolus development 69723 69723 'Rpain' mRNA 371 372 331 19.03 18.89 18.22 27.55 31.6 27.33 18.71333333 28.82666667 613 687 593 358 631 3.65E-11 0.808622271 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016605///PML body GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006606///protein import into nucleus+++GO:0009411///response to UV 69724 69724 'Rnaseh2a' mRNA 552 499 503 22.33 20.36 22.26 23.18 23.95 25.18 21.65 24.10333333 582 610 612 518 601.3333333 0.102064785 0.204027375 03030///DNA replication GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032299///ribonuclease H2 complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0006298///mismatch repair+++GO:0006401///RNA catabolic process+++GO:0016070///RNA metabolic process+++GO:0043137///DNA replication, removal of RNA primer+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 69726 69726 'Smyd3' mRNA 1066.55 1048.36 1028.3 22.51 21.88 22.53 8.65 7.78 8.83 22.30666667 8.42 477.72 447.65 438.15 1047.736667 454.5066667 4.96E-36 -1.218388569 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000993///RNA polymerase II complex binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0046872///metal ion binding GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006469///negative regulation of protein kinase activity+++GO:0014904///myotube cell development+++GO:0032259///methylation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0034968///histone lysine methylation+++GO:0045184///establishment of protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071549///cellular response to dexamethasone stimulus 69727 69727 'Usp46' mRNA 1977 1989 2017 28.25 27.53 29.9 13.44 11.95 12.5 28.56 12.63 1095 950 987 1994.333333 1010.666667 2.26E-34 -0.99474376 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0101005///ubiquitinyl hydrolase activity "GO:0001662///behavioral fear response+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007610///behavior+++GO:0008343///adult feeding behavior+++GO:0016579///protein deubiquitination+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0048149///behavioral response to ethanol+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0060013///righting reflex+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization" 69731 69731 'Gemin7' mRNA 1373 1345 1390 124.56 121.02 133.82 120.13 128.29 121.75 126.4666667 123.39 1515 1575 1482 1369.333333 1524 0.125375313 0.141678785 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:0097504///Gemini of coiled bodies+++GO:0120114///Sm-like protein family complex GO:0005515///protein binding GO:0000387///spliceosomal snRNP assembly+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 69736 69736 'Nup37' mRNA 189 174 191 9.02 8.23 9.67 13.49 12.9 11.44 8.973333333 12.61 325 302 266 184.6666667 297.6666667 7.94E-05 0.674450502 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0031080///nuclear pore outer ring" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051301///cell division 69737 69737 'Ttl' mRNA 198 232 170 2.33 2.68 2.12 2.33 1.6 2.27 2.376666667 2.066666667 228 153 215 200 198.6666667 0.943750036 -0.019388331 GO:0005874///microtubule+++GO:0005876///spindle microtubule GO:0000166///nucleotide binding+++GO:0004835///tubulin-tyrosine ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018166///C-terminal protein-tyrosinylation+++GO:0030516///regulation of axon extension+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0090235///regulation of metaphase plate congression 69740 69740 'Dph5' mRNA 303.04 281.07 260.19 11.58 10.43 10.42 13.87 12.8 13.61 10.81 13.42666667 419.62 377.81 398.4 281.4333333 398.61 4.91E-04 0.48953706 GO:0005575///cellular_component GO:0004164///diphthine synthase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0032259///methylation 69742 69742 'Tm2d2' mRNA 2838 3086 3011 134.39 144.27 151.28 136.58 143.2 136.16 143.3133333 138.6466667 3311 3386 3192 2978.333333 3296.333333 0.083833343 0.133830678 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69743 69743 'Casz1' mRNA 875 877 581 7.07 6.94 5.39 1.32 1.29 1.84 6.466666667 1.483333333 183 164 233 777.6666667 193.3333333 4.61E-36 -2.011283163 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0045596///negative regulation of cell differentiation+++GO:0045664///regulation of neuron differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060040///retinal bipolar neuron differentiation+++GO:0060223///retinal rod cell fate commitment+++GO:0060226///negative regulation of retinal cone cell fate commitment+++GO:1902870///negative regulation of amacrine cell differentiation" 69745 69745 'Pold4' mRNA 446 493 429 31.72 34.7 32.37 46.05 45.22 43.36 32.93 44.87666667 742 710 675 456 709 1.00E-08 0.626131695 03030///DNA replication+++03410///Base excision repair+++03420///Nucleotide excision repair+++03430///Mismatch repair+++03440///Homologous recombination GO:0005634///nucleus+++GO:0043625///delta DNA polymerase complex GO:0003887///DNA-directed DNA polymerase activity GO:0000731///DNA synthesis involved in DNA repair+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus 69747 69747 'Zswim7' mRNA 205 180 184 18.97 16.52 18.07 19.9 20.52 21.2 17.85333333 20.54 246 247 253 189.6666667 248.6666667 0.034627526 0.37922306 GO:0005634///nucleus+++GO:0097196///Shu complex GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0050821///protein stabilization 69748 69748 'Aldh16a1' mRNA 518.14 481.33 486.38 11.25 10.27 11.21 19.02 19.41 17.4 10.91 18.61 1010.16 1007.04 893.89 495.2833333 970.3633333 2.75E-20 0.958469828 "GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor" 69752 69752 'Zfp511' mRNA 541.21 636.28 561.98 22.25 25.79 24.61 21.19 20.24 24.32 24.21666667 21.91666667 554.27 514 603.2 579.8233333 557.1566667 0.664805212 -0.067858114 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 69754 69754 'Fbxo7' mRNA 1288.49 1403.84 1323.45 37.43 40.22 40.95 30.74 35.34 33.05 39.53333333 33.04333333 1219.22 1345.07 1234.14 1338.593333 1266.143333 0.389792055 -0.090777174 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0097409///glial cytoplasmic inclusion+++GO:0097414///classical Lewy body+++GO:0097462///Lewy neurite+++GO:1990037///Lewy body core+++GO:1990038///Lewy body corona "GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0046982///protein heterodimerization activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0000422///autophagy of mitochondrion+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006626///protein targeting to mitochondrion+++GO:0010975///regulation of neuron projection development+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0040012///regulation of locomotion+++GO:0045620///negative regulation of lymphocyte differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1901215///negative regulation of neuron death+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 69757 69757 'Leng1' mRNA 652.4 689.56 661.49 16.61 17.29 17.87 12.08 11.76 10.87 17.25666667 11.57 545.48 518.69 475.39 667.8166667 513.1866667 5.49E-04 -0.392884951 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69769 69769 'Tnfaip8l2' mRNA 81 72 71 4.42 3.81 3.98 40.03 39.72 32.3 4.07 37.35 831 810 655 74.66666667 765.3333333 3.31E-97 3.34606874 GO:0005737///cytoplasm GO:0005515///protein binding GO:0002376///immune system process+++GO:0042981///regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0050728///negative regulation of inflammatory response+++GO:0050868///negative regulation of T cell activation 69770 69770 'Fam174c' mRNA 233 227 177 26.36 25.53 21.25 20.11 19.45 19.21 24.38 19.59 203 191 187 212.3333333 193.6666667 0.524556287 -0.140436921 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69772 69772 'Bdh2' mRNA 3863 3917 3914 206.72 207.57 222.88 78.34 77.99 79.85 212.39 78.72666667 1680 1627 1657 3898 1654.666667 2.05E-80 -1.24912776 00650///Butanoate metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003858///3-hydroxybutyrate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0051287///NAD binding" GO:0006635///fatty acid beta-oxidation+++GO:0019290///siderophore biosynthetic process+++GO:0030855///epithelial cell differentiation+++GO:0042168///heme metabolic process+++GO:0055072///iron ion homeostasis 69773 69773 'Timm29' mRNA 1683 1971 1559 29.05 33.48 28.55 18.96 26.8 23.72 30.36 23.16 1264 1745 1531 1737.666667 1513.333333 0.104479789 -0.204452894 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042721///TIM22 mitochondrial import inner membrane insertion complex GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane 69774 69774 'Ms4a6b' mRNA 150 226 205 5.17 7.67 7.49 89.34 98.21 90.47 6.776666667 92.67333333 2980.08 3197.2 2920.12 193.6666667 3032.466667 4.27E-275 3.957195238 GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69780 69780 'Smap2' mRNA 410 443 450 7.77 8.25 9.11 8.19 7.58 7.43 8.376666667 7.733333333 493 447 440 434.3333333 460 0.685474816 0.06867877 04144///Endocytosis GO:0005737///cytoplasm GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 69784 69784 '1500009L16Rik' mRNA 30 39 48 1.54 1.97 2.61 4.26 4.22 3.88 2.04 4.12 96 92 84 39 90.66666667 2.55E-04 1.198881972 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69786 69786 'Tprkb' mRNA 8190.44 8425.98 8018.85 195.63 199.73 205.79 85.8 92.95 87.99 200.3833333 88.91333333 3935.01 4130.24 3807.66 8211.756667 3957.636667 1.09E-73 -1.064308201 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019901///protein kinase binding GO:0000722///telomere maintenance via recombination+++GO:0002949///tRNA threonylcarbamoyladenosine modification+++GO:0008033///tRNA processing 69787 69787 'Anxa13' mRNA 2 3 0 0.08 0.13 0 0 0 0 0.07 0 0 0 0 1.666666667 0 0.385064596 -3.153564358 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0019898///extrinsic component of membrane+++GO:0031410///cytoplasmic vesicle GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:1901611///phosphatidylglycerol binding 69790 69790 'Med30' mRNA 393 415 338 29.94 31.31 27.32 28 25.47 27.2 29.52333333 26.89 421 373 395 382 396.3333333 0.813854078 0.043699142 04919///Thyroid hormone signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0046966///thyroid hormone receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter" 69792 69792 'Med6' mRNA 476 419 441 28.28 24.81 27.86 23.98 25.63 25.64 26.98333333 25.08333333 462 477 477 445.3333333 472 0.662755492 0.071871145 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0061630///ubiquitin protein ligase activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II 69802 69802 'Cox11' mRNA 501.78 500.39 142.56 12.49 12.27 3.76 2.98 7.94 6.63 9.506666667 5.85 137.47 358.2 296.56 381.5766667 264.0766667 0.546893828 -0.509140815 00190///Oxidative phosphorylation+++04714///Thermogenesis GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031304///intrinsic component of mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0032991///protein-containing complex GO:0005507///copper ion binding+++GO:0005515///protein binding GO:0033132///negative regulation of glucokinase activity+++GO:0055065///metal ion homeostasis 69804 69804 'Tmem147' mRNA 1790 1917 1596 136.94 145.24 129.57 157.7 152.65 153.24 137.25 154.53 2361 2226 2216 1767.666667 2267.666667 9.69E-07 0.349933023 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0043022///ribosome binding 69806 69806 'Slc39a11' mRNA 310 322 333 6.09 6.33 7.08 9.22 11.48 10.1 6.5 10.26666667 534 648 569 321.6666667 583.6666667 3.90E-10 0.848016416 05010///Alzheimer disease+++05012///Parkinson disease GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport 69807 69807 'Trim32' mRNA 1829 1980 1854 31.23 33.36 33.66 32.1 30.73 28.28 32.75 30.37 2158 2021 1842 1887.666667 2007 0.424615296 0.075996611 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005863///striated muscle myosin thick filament GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017022///myosin binding+++GO:0031369///translation initiation factor binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0043621///protein self-association+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0001894///tissue homeostasis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007014///actin ubiquitination+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0032897///negative regulation of viral transcription+++GO:0034612///response to tumor necrosis factor+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045444///fat cell differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045787///positive regulation of cell cycle+++GO:0045862///positive regulation of proteolysis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046716///muscle cell cellular homeostasis+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0050769///positive regulation of neurogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051155///positive regulation of striated muscle cell differentiation+++GO:0061564///axon development+++GO:0070936///protein K48-linked ubiquitination+++GO:1902173///negative regulation of keratinocyte apoptotic process+++GO:1902187///negative regulation of viral release from host cell+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1903883///positive regulation of interleukin-17-mediated signaling pathway+++GO:1903886///positive regulation of chemokine (C-C motif) ligand 20 production+++GO:2000147///positive regulation of cell motility" 69809 69809 '1810046K07Rik' mRNA 29 50 35 1.45 2.47 1.86 0 0.18 0.05 1.926666667 0.076666667 0 4 1 38 1.666666667 1.66E-07 -4.513802318 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69810 69810 'Clec4b1' mRNA 3 3 2 0.26 0.26 0.19 0.61 1.27 0.9 0.236666667 0.926666667 8 14 10 2.666666667 10.66666667 0.061252727 1.998140401 04625///C-type lectin receptor signaling pathway GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding "GO:0001818///negative regulation of cytokine production+++GO:0002470///plasmacytoid dendritic cell antigen processing and presentation+++GO:0006955///immune response+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0044419///interspecies interaction between organisms+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0061760///antifungal innate immune response" 69814 69814 'Prss32' mRNA 0 5 7 0 0.2 0.3 0.07 0.04 0.11 0.166666667 0.073333333 2 1 3 4 2 0.594048297 -1.035958009 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007283///spermatogenesis 69815 69815 'Krtcap3' mRNA 305 295 252 22.07 21.15 19.36 20.6 19.89 18.04 20.86 19.51 326 307 276 284 303 0.673312899 0.08384935 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69816 69816 'Mzb1' mRNA 15 15 15 1.09 1.08 1.15 2.02 3.37 2.68 1.106666667 2.69 32 52 41 15 41.66666667 0.003052983 1.466020286 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0034663///endoplasmic reticulum chaperone complex GO:0003674///molecular_function+++GO:0005515///protein binding GO:0002639///positive regulation of immunoglobulin production+++GO:0008284///positive regulation of cell proliferation+++GO:0030888///regulation of B cell proliferation+++GO:0033622///integrin activation+++GO:0042127///regulation of cell proliferation+++GO:0046626///regulation of insulin receptor signaling pathway 69821 69821 'Mterf4' mRNA 391 389 331 17.78 17.45 16.01 11.9 12.97 12.28 17.08 12.38333333 300 318 300 370.3333333 306 0.056746365 -0.283811731 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005829///cytosol GO:0003690///double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0019843///rRNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006364///rRNA processing+++GO:0006390///mitochondrial transcription+++GO:0006626///protein targeting to mitochondrion+++GO:0007507///heart development+++GO:0042255///ribosome assembly+++GO:0043010///camera-type eye development" 69823 69823 'Fyttd1' mRNA 1250.54 1269.96 1306.73 18.79 18.21 20.36 19.02 19.13 19.09 19.12 19.08 1510.11 1438.48 1434.03 1275.743333 1460.873333 0.040506857 0.182505042 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006406///mRNA export from nucleus+++GO:0051028///mRNA transport 69824 69824 'Glod5' mRNA 22.08 18.02 23.22 1.52 1.22 1.74 0.9 1.23 1.38 1.493333333 1.17 14.95 19.97 21.66 21.10666667 18.86 0.750387006 -0.235546165 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 69833 69833 'Polr2f' mRNA 994 914 937 137.23 125.8 137.33 137.35 153.74 150.65 133.4533333 147.2466667 1134 1233 1198 948.3333333 1188.333333 0.00108846 0.314043777 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05016///Huntington disease "GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005666///RNA polymerase III complex+++GO:0005736///RNA polymerase I complex" GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II" 69834 69834 'Rab43' mRNA 356 354 271 4.3 4.15 3.47 5.62 5.25 6.04 3.973333333 5.636666667 529 485 557 327 523.6666667 5.57E-07 0.671915818 GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0000045///autophagosome assembly+++GO:0006886///intracellular protein transport+++GO:0007030///Golgi organization+++GO:0019068///virion assembly+++GO:0035526///retrograde transport, plasma membrane to Golgi+++GO:0071346///cellular response to interferon-gamma+++GO:0090382///phagosome maturation+++GO:1901998///toxin transport" 69836 69836 'Pla2g12b' mRNA 0 1 2 0 0.06 0.11 0.08 0.16 0.05 0.056666667 0.096666667 2 3 1 1 2 0.720620081 0.96673346 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00592///alpha-Linolenic acid metabolism+++04014///Ras signaling pathway+++04270///Vascular smooth muscle contraction+++04972///Pancreatic secretion+++04975///Fat digestion and absorption GO:0005575///cellular_component+++GO:0005576///extracellular region "GO:0003674///molecular_function+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)" GO:0006644///phospholipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0042632///cholesterol homeostasis+++GO:0050482///arachidonic acid secretion+++GO:0070328///triglyceride homeostasis 69837 69837 'Pcgf1' mRNA 463 456 378 29.55 30.29 25.97 15.09 15.88 15.47 28.60333333 15.48 257 267 244 432.3333333 256 4.55E-08 -0.764095891 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly+++GO:0035518///histone H2A monoubiquitination+++GO:0036353///histone H2A-K119 monoubiquitination 69847 69847 'Wnk4' mRNA 850 810 731 10.97 10.27 10.01 11.95 10.41 10.94 10.41666667 11.1 1066 907 949 797 974 0.005445906 0.27814345 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019870///potassium channel inhibitor activity GO:0006468///protein phosphorylation+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0008104///protein localization+++GO:0010766///negative regulation of sodium ion transport+++GO:0016310///phosphorylation+++GO:0030644///cellular chloride ion homeostasis+++GO:0035556///intracellular signal transduction+++GO:0050794///regulation of cellular process+++GO:0050801///ion homeostasis+++GO:0070294///renal sodium ion absorption+++GO:0072156///distal tubule morphogenesis+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:1903288///positive regulation of potassium ion import+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 69852 69852 'Tcf23' mRNA 0 3 0 0 0.25 0 0.12 0 0.16 0.083333333 0.093333333 2 0 2 1 1.333333333 0.894900841 0.43160934 GO:0000791///euchromatin+++GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0032502///developmental process+++GO:0046697///decidualization+++GO:0051148///negative regulation of muscle cell differentiation 69860 69860 'Eif1ad' mRNA 734 736 684 16.51 16.29 16.34 17.93 17.42 18.27 16.38 17.87333333 918 868 903 718 896.3333333 0.001264126 0.308880293 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity GO:0006413///translational initiation 69863 69863 'Ttc39b' mRNA 975 966 865 6.98 7.41 6.12 5.85 5.27 5.88 6.836666667 5.666666667 750 658 777 935.3333333 728.3333333 2.24E-04 -0.371562641 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006629///lipid metabolic process+++GO:0010874///regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0042632///cholesterol homeostasis+++GO:0090181///regulation of cholesterol metabolic process 69865 69865 'A1cf' mRNA 3.12 2 0 0.02 0.02 0 0.01 0.03 0.01 0.013333333 0.016666667 1.19 4 1 1.706666667 2.063333333 0.903981844 0.289594233 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030895///apolipoprotein B mRNA editing enzyme complex+++GO:0045293///mRNA editing complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0006397///mRNA processing+++GO:0007566///embryo implantation+++GO:0010609///mRNA localization resulting in posttranscriptional regulation of gene expression+++GO:0016554///cytidine to uridine editing+++GO:0016556///mRNA modification+++GO:0050714///positive regulation of protein secretion+++GO:0050821///protein stabilization 69870 69870 'Polr3gl' mRNA 1559.25 1682.54 1487.86 42.4 44.18 41.89 21.21 22.63 22.92 42.82333333 22.25333333 842.69 878.66 842.36 1576.55 854.57 8.39E-28 -0.893909834 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex GO:0003682///chromatin binding GO:0006383///transcription by RNA polymerase III 69871 69871 'Ppp1r35' mRNA 229 222 39 15.33 14.83 2.73 5.49 7.39 7.5 10.96333333 6.793333333 94 123 124 163.3333333 113.6666667 0.587999274 -0.501963838 GO:0005575///cellular_component GO:0004864///protein phosphatase inhibitor activity+++GO:0019902///phosphatase binding GO:0010923///negative regulation of phosphatase activity 69875 69875 'Ndufa11' mRNA 3222 3193 3151 67.11 65.47 69.62 57.85 66.66 64.24 67.4 62.91666667 3195 3595 3435 3188.666667 3408.333333 0.324163144 0.085132637 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070469///respiratory chain GO:0003674///molecular_function GO:0032981///mitochondrial respiratory chain complex I assembly 69876 69876 'Thap3' mRNA 770 860 774 43.23 47.63 45.98 27.18 29.1 29.16 45.61333333 28.48 557 581 576 801.3333333 571.3333333 1.88E-06 -0.49861223 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0045944///positive regulation of transcription by RNA polymerase II 69878 69878 'Snrpf' mRNA 497.96 462.95 570.94 41.51 38.24 50.5 49 55.63 54.37 43.41666667 53 672.9 743.96 720.95 510.6166667 712.6033333 4.41E-04 0.466028028 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005683///U7 snRNP+++GO:0005685///U1 snRNP+++GO:0005687///U4 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0034709///methylosome+++GO:0034715///pICln-Sm protein complex+++GO:0034719///SMN-Sm protein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000387///spliceosomal snRNP assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 69882 69882 'Ints14' mRNA 683 720 686 12.89 13.32 13.71 14.18 13.95 14.96 13.30666667 14.36333333 868 829 884 696.3333333 860.3333333 0.00351797 0.293203598 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0034472///snRNA 3'-end processing 69885 69885 'Aunip' mRNA 6 0 1 0.29 0 0.05 1 0.68 1.51 0.113333333 1.063333333 24 16 35 2.333333333 25 1.96E-04 3.414146894 GO:0000922///spindle pole+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0090734///site of DNA damage GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007051///spindle organization+++GO:0008150///biological_process+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining 69888 69888 'Cyp2c66' mRNA 0 1 0 0 0.04 0 0 0 0.03 0.013333333 0.01 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0101020///estrogen 16-alpha-hydroxylase activity" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 69890 69890 'Zfp219' mRNA 1598.9 1577.19 1403.06 28.24 28.05 27.13 20.88 19.6 19.56 27.80666667 20.01333333 1287.43 1189.45 1198.02 1526.383333 1224.966667 3.23E-05 -0.327767392 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060174///limb bud formation" 69893 69893 'Coa7' mRNA 364 372 328 6.97 7.01 6.67 7.73 8.37 8.7 6.883333333 8.266666667 464 491 506 354.6666667 487 5.15E-04 0.448192639 04714///Thermogenesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0003674///molecular_function GO:0008150///biological_process 69894 69894 'Fam241b' mRNA 824 807 789 26.42 25.56 26.73 14.39 13.35 16.2 26.23666667 14.64666667 513 466 556 806.6666667 511.6666667 6.27E-10 -0.668956238 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding GO:0008150///biological_process 69900 69900 'Mfsd11' mRNA 1067.23 1177.74 1024.58 23.13 25.55 23.36 37.65 37.43 35.94 24.01333333 37.00666667 1965.11 1884.9 1808.14 1089.85 1886.05 2.54E-24 0.781082336 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 69902 69902 'Mrto4' mRNA 447.71 458.98 498.62 22.55 22.81 26.62 29.57 33.56 30.63 23.99333333 31.25333333 673.85 745.88 674.87 468.4366667 698.2 4.25E-06 0.562875414 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030687///preribosome, large subunit precursor" GO:0000027///ribosomal large subunit assembly+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis 69903 69903 'Rasip1' mRNA 491 498 361 8.53 8.51 6.65 3.29 3.85 3.65 7.896666667 3.596666667 218 249 234 450 233.6666667 4.61E-10 -0.94999255 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005911///cell-cell junction+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0051020///GTPase binding GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0010507///negative regulation of autophagy+++GO:0033625///positive regulation of integrin activation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:1905709///negative regulation of membrane permeability+++GO:2000299///negative regulation of Rho-dependent protein serine/threonine kinase activity 69906 69906 'Slc25a32' mRNA 559.81 494 588.98 6.48 5.72 7.39 5.63 5.45 6.02 6.53 5.7 528.2 474.99 499.55 547.5966667 500.9133333 0.33319691 -0.144817456 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008517///folic acid transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity GO:0006862///nucleotide transport+++GO:0055085///transmembrane transport+++GO:1904947///folate import into mitochondrion+++GO:1990548///mitochondrial FAD transmembrane transport 69908 69908 'Rab3b' mRNA 123 86 107 2.02 1.39 1.87 0.8 0.89 0.97 1.76 0.886666667 56 61 66 105.3333333 61 0.006321303 -0.801173143 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0098691///dopaminergic synapse+++GO:0098993///anchored component of synaptic vesicle membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0030742///GTP-dependent protein binding+++GO:0031489///myosin V binding GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0018125///peptidyl-cysteine methylation+++GO:0019882///antigen processing and presentation+++GO:0051586///positive regulation of dopamine uptake involved in synaptic transmission+++GO:0072659///protein localization to plasma membrane+++GO:0097494///regulation of vesicle size+++GO:0098693///regulation of synaptic vesicle cycle 69912 69912 'Nup43' mRNA 143 162 170 6.72 7.51 8.47 10.15 10.95 11.55 7.566666667 10.88333333 248 261 273 158.3333333 260.6666667 1.10E-04 0.70583742 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0031080///nuclear pore outer ring" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051301///cell division 69917 69917 'Nabp2' mRNA 1074 994 1121 59.52 54.43 66.25 47.96 55.15 52.52 60.06666667 51.87666667 992 1103 1049 1063 1048 0.817136339 -0.034164461 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0035861///site of double-strand break+++GO:0070876///SOSS complex" GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0070182///DNA polymerase binding+++GO:0098505///G-rich strand telomeric DNA binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007093///mitotic cell cycle checkpoint+++GO:0010212///response to ionizing radiation+++GO:0044818///mitotic G2/M transition checkpoint+++GO:0070200///establishment of protein localization to telomere+++GO:1904355///positive regulation of telomere capping 69920 69920 'Polr2i' mRNA 471 472 464.59 49.06 48.83 51.36 36.09 41.4 42.89 49.75 40.12666667 396 442 454 469.1966667 430.6666667 0.373657224 -0.133954045 03020///RNA polymerase+++05016///Huntington disease "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005665///RNA polymerase II, core complex+++GO:0005730///nucleolus" GO:0003676///nucleic acid binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0001193///maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006351///transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006379///mRNA cleavage" 69922 69922 'Vrk2' mRNA 220.97 256.97 245.25 7.57 8.92 9.07 8.52 9.15 7.54 8.52 8.403333333 276.37 309.13 247.28 241.0633333 277.5933333 0.318200634 0.194779188 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0034599///cellular response to oxidative stress+++GO:0043408///regulation of MAPK cascade+++GO:0046777///protein autophosphorylation+++GO:2000659///regulation of interleukin-1-mediated signaling pathway 69923 69923 'Agk' mRNA 705.33 677.23 633.2 14.46 13.72 14.02 10.41 11.59 10.7 14.06666667 10.9 559.53 619.67 568.27 671.92 582.49 0.066579142 -0.216524001 00561///Glycerolipid metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0042721///TIM22 mitochondrial import inner membrane insertion complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0001727///lipid kinase activity+++GO:0001729///ceramide kinase activity+++GO:0003951///NAD+ kinase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0017050///D-erythro-sphingosine kinase activity+++GO:0047620///acylglycerol kinase activity+++GO:0102773///dihydroceramide kinase activity GO:0006665///sphingolipid metabolic process+++GO:0016310///phosphorylation+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0046486///glycerolipid metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0046834///lipid phosphorylation 69926 69926 'Dnah17' mRNA 54 48 43 0.19 0.17 0.16 0.2 0.14 0.12 0.173333333 0.153333333 65 45 37 48.33333333 49 0.996200074 0.006715799 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0036157///outer dynein arm+++GO:0042995///cell projection "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement+++GO:0036158///outer dynein arm assembly 69928 69928 'Cenps' mRNA 29 18 20 2.03 1.25 1.49 4.83 4.45 5.31 1.59 4.863333333 79 71 84 22.33333333 78 1.22E-06 1.793286841 03460///Fanconi anemia pathway "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0043240///Fanconi anaemia nuclear complex+++GO:0071821///FANCM-MHF complex" GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0046982///protein heterodimerization activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0031297///replication fork processing+++GO:0051301///cell division+++GO:0051382///kinetochore assembly 69930 69930 'Zfp715' mRNA 348 430 412 4.46 5.42 5.65 4.91 5.3 4.52 5.176666667 4.91 442 465 395 396.6666667 434 0.504134736 0.116937945 05168///Herpes simplex virus 1 infection GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 69934 69934 'Trmt10b' mRNA 216 241 199 5.99 6.58 5.91 6.05 4.42 5.77 6.16 5.413333333 252 179 231 218.6666667 220.6666667 0.998591786 0.001540914 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000049///tRNA binding+++GO:0008168///methyltransferase activity+++GO:0009019///tRNA (guanine-N1-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0052905///tRNA (guanine(9)-N(1))-methyltransferase activity GO:0002939///tRNA N1-guanine methylation+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0090646///mitochondrial tRNA processing 69938 69938 'Scrn1' mRNA 2077.9 2175.69 2073.99 63.75 65.67 67.18 26.46 29.62 25.34 65.53333333 27.14 993.06 1089.54 929.18 2109.193333 1003.926667 7.39E-38 -1.082029554 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0003674///molecular_function+++GO:0016805///dipeptidase activity+++GO:0070004///cysteine-type exopeptidase activity GO:0006508///proteolysis+++GO:0006887///exocytosis 69940 69940 'Exoc1' mRNA 658 697 724 10.62 11.06 12.4 11.53 10.37 11.3 11.36 11.06666667 817 717 774 693 769.3333333 0.27089855 0.136032556 GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0090543///Flemming body+++GO:0098592///cytoplasmic side of apical plasma membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding" GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0007566///embryo implantation+++GO:0015031///protein transport+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050714///positive regulation of protein secretion 69942 69942 'Rnf113a1' mRNA 109 127 155 5.33 6.14 8.05 4.48 4.11 4.59 6.506666667 4.393333333 105 94 104 130.3333333 101 0.156784326 -0.386720227 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005684///U2-type spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0034247///snoRNA splicing 69944 69944 '2810021J22Rik' mRNA 283.54 235.29 252 3.33 2.57 3.05 2.05 1.95 2.27 2.983333333 2.09 205 190.24 217.23 256.9433333 204.1566667 0.060722514 -0.343963141 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 69955 69955 'Fars2' mRNA 835.08 791.36 755.75 23.63 23.63 23.47 13.75 14.41 16.11 23.57666667 14.75666667 589.29 591.77 640.37 794.0633333 607.1433333 1.45E-04 -0.398337977 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004826///phenylalanine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0008033///tRNA processing+++GO:0043039///tRNA aminoacylation 69956 69956 'Ptcd3' mRNA 683 737 687 14.81 15.64 15.68 13.88 13.92 13.16 15.37666667 13.65333333 739 724 680 702.3333333 714.3333333 0.926028199 0.012763468 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005886///plasma membrane GO:0003723///RNA binding+++GO:0019843///rRNA binding+++GO:0043024///ribosomal small subunit binding GO:0006417///regulation of translation+++GO:0032543///mitochondrial translation 69957 69957 'Cdc16' mRNA 1183 1312 1239 28.41 31.04 31.62 29.68 34.44 34.85 30.35666667 32.99 1421 1610 1614 1244.666667 1548.333333 0.001421845 0.304272145 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0072686///mitotic spindle GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination 69961 69961 'Rpp25l' mRNA 858 825 854 68.62 65.36 72.48 80.67 87.7 83.83 68.82 84.06666667 1155 1223 1159 845.6666667 1179 5.89E-07 0.467127843 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0001682///tRNA 5'-leader removal 69962 69962 'Mettl18' mRNA 158 149 140 6.37 5.97 6.06 5.13 5.26 5.06 6.133333333 5.15 145 143 139 149 142.3333333 0.782061644 -0.076743794 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018064///protein-histidine N-methyltransferase activity+++GO:0031072///heat shock protein binding "GO:0006417///regulation of translation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0032259///methylation+++GO:0042038///peptidyl-histidine methylation, to form tele-methylhistidine+++GO:0090069///regulation of ribosome biogenesis+++GO:2000232///regulation of rRNA processing" 69976 69976 'Galk2' mRNA 643 755 707.69 19.43 22.31 22.45 33.8 31.06 33.44 21.39666667 32.76666667 1286 1156 1230.94 701.8966667 1224.313333 1.91E-16 0.789790623 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0004335///galactokinase activity+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0033858///N-acetylgalactosamine kinase activity" GO:0005975///carbohydrate metabolic process+++GO:0006012///galactose metabolic process+++GO:0006071///glycerol metabolic process+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0016310///phosphorylation+++GO:0019563///glycerol catabolic process+++GO:0046167///glycerol-3-phosphate biosynthetic process+++GO:0046835///carbohydrate phosphorylation 69981 69981 'Tmem30a' mRNA 4383 4712 3545 64.96 68.7 55.73 48.37 58.53 58.36 63.13 55.08666667 3756 4440 4389 4213.333333 4195 0.930263498 -0.010650072 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:1990531///phospholipid-translocating ATPase complex GO:0005515///protein binding+++GO:0015247///aminophospholipid transmembrane transporter activity GO:0006855///drug transmembrane transport+++GO:0006869///lipid transport+++GO:0010976///positive regulation of neuron projection development+++GO:0015914///phospholipid transport+++GO:0015917///aminophospholipid transport+++GO:0031175///neuron projection development+++GO:0036010///protein localization to endosome+++GO:0045332///phospholipid translocation+++GO:0061092///positive regulation of phospholipid translocation+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum 69982 69982 'Spink2' mRNA 1 3 3 0.15 0.35 0.38 0.81 0.43 0.28 0.293333333 0.506666667 6 4 2 2.333333333 4 0.673276919 0.754499732 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity GO:0001675///acrosome assembly+++GO:0002176///male germ cell proliferation+++GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0010466///negative regulation of peptidase activity+++GO:0030154///cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0072520///seminiferous tubule development+++GO:1900004///negative regulation of serine-type endopeptidase activity 69987 69987 'Spaca9' mRNA 64 70 51 6.93 7.54 5.86 6.07 6.63 5.01 6.776666667 5.903333333 64 68 51 61.66666667 61 0.961056105 -0.02229695 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0048306///calcium-dependent protein binding GO:0008150///biological_process 69993 69993 'Chn2' mRNA 755.17 830.4 670.13 13.03 13.93 12.53 7.78 8.39 8.46 13.16333333 8.21 563.42 588.67 569.13 751.9 573.74 2.50E-04 -0.398826772 GO:0016020///membrane+++GO:0045202///synapse GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction 69994 69994 'Rsc1a1' mRNA 86.78 98.48 135.63 2.28 2.54 3.77 2.88 2.87 3.11 2.863333333 2.953333333 126.45 122.66 132.14 106.9633333 127.0833333 0.453590728 0.23176297 GO:0001917///photoreceptor inner segment+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0098984///neuron to neuron synapse "GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0019871///sodium channel inhibitor activity+++GO:0031210///phosphatidylcholine binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0010829///negative regulation of glucose transmembrane transport+++GO:0010842///retina layer formation+++GO:0016062///adaptation of rhodopsin mediated signaling+++GO:0032243///negative regulation of nucleoside transport+++GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0045920///negative regulation of exocytosis+++GO:0050892///intestinal absorption+++GO:0050896///response to stimulus+++GO:0051051///negative regulation of transport+++GO:0051260///protein homooligomerization+++GO:1903077///negative regulation of protein localization to plasma membrane" 70008 70008 'Ace2' mRNA 51 31 43 0.78 0.49 0.71 0.22 0.51 0.27 0.66 0.333333333 16 36 19 41.66666667 23.66666667 0.112206955 -0.825182666 04614///Renin-angiotensin system+++04974///Protein digestion and absorption+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0042995///cell projection GO:0001618///virus receptor activity+++GO:0004175///endopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008241///peptidyl-dipeptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0003051///angiotensin-mediated drinking behavior+++GO:0003081///regulation of systemic arterial blood pressure by renin-angiotensin+++GO:0006508///proteolysis+++GO:0015827///tryptophan transport+++GO:0022898///regulation of transmembrane transporter activity+++GO:0046718///viral entry into host cell+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0051957///positive regulation of amino acid transport+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:1903598///positive regulation of gap junction assembly+++GO:1903779///regulation of cardiac conduction+++GO:1905737///positive regulation of L-proline import across plasma membrane+++GO:2000272///negative regulation of signaling receptor activity 70012 70012 'Cep85' mRNA 364 377 389 5.11 5.36 5.76 4.33 4.25 4.99 5.41 4.523333333 356 333 398 376.6666667 362.3333333 0.717331562 -0.069448856 GO:0000242///pericentriolar material+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0001764///neuron migration+++GO:0006469///negative regulation of protein kinase activity+++GO:0007059///chromosome segregation+++GO:0046602///regulation of mitotic centrosome separation 70020 70020 'Ino80b' mRNA 93 110 33 4.8 5.61 1.81 1.58 1.8 1.82 4.073333333 1.733333333 35 39 39 78.66666667 37.66666667 0.013448834 -1.052448914 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031011///Ino80 complex GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043044///ATP-dependent chromatin remodeling 70021 70021 'Nt5dc2' mRNA 84 63 62 3.13 2.28 2.5 7.3 7.75 8.38 2.636666667 7.81 226.17 241.18 249.18 69.66666667 238.8433333 8.08E-17 1.767336165 GO:0005575///cellular_component GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 70024 70024 'Mcm10' mRNA 9 20 6 0.14 0.31 0.1 2.12 1.77 1.33 0.183333333 1.74 157 129 95 11.66666667 127 1.12E-17 3.439984102 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031298///replication fork protection complex GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation 70025 70025 'Acot7' mRNA 1862 1742 1744 80.18 73.45 79.69 54.12 56.3 54.9 77.77333333 55.10666667 1431 1472 1440 1782.666667 1447.666667 8.32E-05 -0.311960698 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0044297///cell body GO:0000062///fatty-acyl-CoA binding+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0015937///coenzyme A biosynthetic process+++GO:0036114///medium-chain fatty-acyl-CoA catabolic process+++GO:0036116///long-chain fatty-acyl-CoA catabolic process+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:1900535///palmitic acid biosynthetic process 70026 70026 'Tspo2' mRNA 31 25 33 1.71 1.29 1.79 0.65 1.3 1.1 1.596666667 1.016666667 13 26 21 29.66666667 20 0.324631496 -0.580456583 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031090///organelle membrane GO:0015485///cholesterol binding GO:0032367///intracellular cholesterol transport+++GO:0034389///lipid droplet organization+++GO:0043353///enucleate erythrocyte differentiation+++GO:0089718///amino acid import across plasma membrane+++GO:0098739///import across plasma membrane 70028 70028 'Dop1b' mRNA 670 694.84 636 10.36 9.73 10.74 9.86 10.69 10.97 10.27666667 10.50666667 935 809 870 666.9466667 871.3333333 1.77E-04 0.374366035 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031901///early endosome membrane GO:0003674///molecular_function GO:0006895///Golgi to endosome transport+++GO:0015031///protein transport+++GO:0050890///cognition 70031 70031 'Cmtm8' mRNA 654 628 540 38.73 36.76 33.93 20.13 19.91 21.07 36.47333333 20.37 390 376 393 607.3333333 386.3333333 1.69E-08 -0.661680259 GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0019911///structural constituent of myelin sheath GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0042552///myelination 70044 70044 'Tut1' mRNA 756 754 768 15.09 14.82 16.27 12.94 12.81 13.16 15.39333333 12.97 745 720 734 759.3333333 733 0.620590861 -0.063879009 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0017070///U6 snRNA binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0050265///RNA uridylyltransferase activity+++GO:1990817///RNA adenylyltransferase activity GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0016180///snRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0034477///U6 snRNA 3'-end processing+++GO:0071044///histone mRNA catabolic process+++GO:0098789///pre-mRNA cleavage required for polyadenylation 70045 70045 '2610528A11Rik' mRNA 1 1 2 0.09 0.09 0.19 0.96 0.74 0.42 0.123333333 0.706666667 12 9 5 1.333333333 8.666666667 0.042577372 2.675953286 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001664///G protein-coupled receptor binding+++GO:0005125///cytokine activity+++GO:0008009///chemokine activity+++GO:0048018///receptor ligand activity GO:0006935///chemotaxis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0042742///defense response to bacterium+++GO:0048247///lymphocyte chemotaxis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0051782///negative regulation of cell division+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:2000404///regulation of T cell migration 70047 70047 'Trnt1' mRNA 906.8 1011.99 999.35 21.7 24.02 25.33 20.29 20.97 19.91 23.68333333 20.39 993.66 981.97 929.98 972.7133333 968.5366667 0.876147748 -0.019671974 GO:0005739///mitochondrion GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004810///tRNA adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0009022///tRNA nucleotidyltransferase activity+++GO:0016437///tRNA cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0052927///CTP:tRNA cytidylyltransferase activity+++GO:0052928///CTP:3'-cytidine-tRNA cytidylyltransferase activity+++GO:0052929///ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity GO:0001680///tRNA 3'-terminal CCA addition+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:1990180///mitochondrial tRNA 3'-end processing 70052 70052 'Prpf4' mRNA 577 538 610 8.33 7.43 8.62 8.62 8.82 8.66 8.126666667 8.7 682 667 672 575 673.6666667 0.087029589 0.213786216 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071001///U4/U6 snRNP+++GO:0071005///U2-type precatalytic spliceosome+++GO:0097525///spliceosomal snRNP complex GO:0017070///U6 snRNA binding+++GO:0030621///U4 snRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 70054 70054 'Ccdc89' mRNA 86 93 59 2.05 2.18 1.49 0.54 0.55 0.49 1.906666667 0.526666667 26 26 23 79.33333333 25 3.68E-06 -1.669735746 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0008150///biological_process 70059 70059 'Degs2' mRNA 452.48 424.14 363.68 15.4 14.86 14.07 20.28 22.56 19.36 14.77666667 20.73333333 575.83 595.01 532.3 413.4333333 567.7133333 3.27E-04 0.449529771 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000170///sphingosine hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0042284///sphingolipid delta-4 desaturase activity GO:0006629///lipid metabolic process+++GO:0006667///sphinganine metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process 70060 70060 'Spata3' mRNA 1 2 2 0.03 0.06 0.12 0.1 0 0.12 0.07 0.073333333 3 0 3 1.666666667 2 0.922545721 0.236338726 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 70061 70061 'Sdr9c7' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity 70069 70069 'H1f7' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding GO:0006997///nucleus organization+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007290///spermatid nucleus elongation+++GO:0030154///cell differentiation+++GO:0030261///chromosome condensation+++GO:0035092///sperm chromatin condensation 70078 70078 'Nol7' mRNA 877.64 866.82 850 27.91 27.17 28.68 19.43 23.04 24.18 27.92 22.21666667 702.21 812.91 845.58 864.82 786.9 0.231671699 -0.146883878 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005739///mitochondrion GO:0008150///biological_process 70080 70080 'Igsf23' mRNA 1 4 5 0.07 0.13 0.29 0.09 0.24 0.12 0.163333333 0.15 3 6 4 3.333333333 4.333333333 0.84347843 0.359447594 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 70081 70081 'Zfp995' mRNA 157.99 134.76 159.1 2.64 2.04 3.12 1.93 1.48 2.18 2.6 1.863333333 145.53 108 155 150.6166667 136.1766667 0.579540549 -0.157804108 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 70082 70082 'Lysmd2' mRNA 691 727 630 35.26 36.47 33.93 22.43 22.34 22.26 35.22 22.34333333 503 490 486 682.6666667 493 8.36E-06 -0.479495295 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70083 70083 'Metrn' mRNA 1226 1164 825 53.97 50.57 38.53 41.6 46.85 47.84 47.69 45.43 1085 1192 1207 1071.666667 1161.333333 0.42216908 0.112699968 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005179///hormone activity GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010001///glial cell differentiation+++GO:0030154///cell differentiation+++GO:0050772///positive regulation of axonogenesis 70086 70086 'Cysltr2' mRNA 48 37 76 1.37 1.03 2.25 0.49 0.25 0.43 1.55 0.39 18 9 15 53.66666667 14 7.78E-05 -1.970232516 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001631///cysteinyl leukotriene receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004974///leukotriene receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0010942///positive regulation of cell death+++GO:0045766///positive regulation of angiogenesis+++GO:0061737///leukotriene signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 70088 70088 'Meaf6' mRNA 705 718 679 8.36 8.39 8.55 4.96 5.54 5.64 8.433333333 5.38 476 522 525 700.6666667 507.6666667 2.04E-05 -0.475315939 "GO:0000123///histone acetyltransferase complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0070776///MOZ/MORF histone acetyltransferase complex+++GO:1990467///NuA3a histone acetyltransferase complex+++GO:1990468///NuA3b histone acetyltransferase complex" GO:0006325///chromatin organization+++GO:0016573///histone acetylation+++GO:0043968///histone H2A acetylation+++GO:0043972///histone H3-K23 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0044154///histone H3-K14 acetylation 70093 70093 'Ube2q1' mRNA 245 306 292 4.36 5.36 5.51 6.62 5.96 6.17 5.076666667 6.25 428 377 386 281 397 0.00149791 0.484574679 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030175///filopodium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0001967///suckling behavior+++GO:0007566///embryo implantation+++GO:0007617///mating behavior+++GO:0009566///fertilization+++GO:0016567///protein ubiquitination+++GO:0061458///reproductive system development+++GO:0070459///prolactin secretion 70097 70097 'Sash1' mRNA 264 247 198 1.91 1.74 1.49 1.88 1.86 2.12 1.713333333 1.953333333 306 293 332 236.3333333 310.3333333 0.021452689 0.385454788 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0001965///G-protein alpha-subunit binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0060090///molecular adaptor activity GO:0000209///protein polyubiquitination+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010632///regulation of epithelial cell migration+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045766///positive regulation of angiogenesis+++GO:1900044///regulation of protein K63-linked ubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1902498///regulation of protein autoubiquitination 70099 70099 'Smc4' mRNA 346 388 309 4.2 4.63 3.99 9.39 9.27 8.94 4.273333333 9.2 888 849 821 347.6666667 852.6666667 6.60E-32 1.285157477 "GO:0000775///chromosome, centromeric region+++GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck" GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0000012///single strand break repair+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0045132///meiotic chromosome segregation+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0051383///kinetochore organization 70101 70101 'Cyp4f16' mRNA 326.95 298.94 247.99 8.33 7.49 6.61 8.01 7.49 7.96 7.476666667 7.82 365.92 331.83 350.16 291.2933333 349.3033333 0.110540314 0.255507253 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" 70103 70103 'Znhit1' mRNA 827.65 770.51 822.74 75.36 68.51 78.98 78.38 80.48 72.84 74.28333333 77.23333333 988.26 996.46 901.14 806.9666667 961.9533333 0.02342168 0.240849107 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003682///chromatin binding+++GO:0031491///nucleosome binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006338///chromatin remodeling+++GO:0031063///regulation of histone deacetylation+++GO:0042129///regulation of T cell proliferation+++GO:0043486///histone exchange+++GO:0070317///negative regulation of G0 to G1 transition 70110 70110 'Ifi35' mRNA 1664 1622 1618 73.45 70.65 75.77 101.98 99.96 102.06 73.29 101.3333333 2653 2537 2568 1634.666667 2586 1.79E-21 0.649254601 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0042802///identical protein binding GO:0002281///macrophage activation involved in immune response+++GO:0002376///immune system process+++GO:0008285///negative regulation of cell proliferation+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0050729///positive regulation of inflammatory response+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 70113 70113 'Odf3b' mRNA 427 433 354 29.32 29.74 26.5 3.86 4.15 4.36 28.52 4.123333333 63 70 71 404.6666667 68 5.32E-47 -2.58069626 GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 70118 70118 'Srrd' mRNA 20.27 42.09 39.88 1.16 2.39 2.43 2.43 0.96 1.22 1.993333333 1.536666667 48.42 18.82 23.67 34.08 30.30333333 0.763942705 -0.207197394 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006783///heme biosynthetic process+++GO:0007017///microtubule-based process+++GO:0042752///regulation of circadian rhythm+++GO:0048511///rhythmic process+++GO:0070453///regulation of heme biosynthetic process 70120 70120 'Yars2' mRNA 277 262 76 10.23 9.54 2.98 3.57 7.11 6.38 7.583333333 5.686666667 111 216 192 205 173 0.79168756 -0.225804115 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004831///tyrosine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042803///protein homodimerization activity+++GO:0072545///tyrosine binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006437///tyrosyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0070184///mitochondrial tyrosyl-tRNA aminoacylation 70122 70122 'Mllt3' mRNA 1363 1280 1212 17.26 15.72 16.54 11.47 9.9 12.01 16.50666667 11.12666667 1063 975 1036 1285 1024.666667 7.47E-05 -0.337924764 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0070577///lysine-acetylated histone binding+++GO:0140030///modification-dependent protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0009952///anterior/posterior pattern specification+++GO:0010467///gene expression+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060218///hematopoietic stem cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1902275///regulation of chromatin organization+++GO:2000035///regulation of stem cell division+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway" 70123 70123 'Nbdy' mRNA 697 706 657 54.3 54.48 54.32 70.82 69.07 65.86 54.36666667 68.58333333 1041 989 935 686.6666667 988.3333333 4.43E-08 0.513950858 GO:0000932///P-body GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0010607///negative regulation of cytoplasmic mRNA processing body assembly 70127 70127 'Dpf3' mRNA 275 214 214 9.11 7.04 7.53 2.03 1.11 1.26 7.893333333 1.466666667 81 39 44 234.3333333 54.66666667 3.15E-16 -2.115727451 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071565///nBAF complex GO:0003712///transcription coregulator activity+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0007399///nervous system development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 70129 70129 'Slc44a4' mRNA 166 157 192 4.02 3.69 4.94 3.67 2.82 3.18 4.216666667 3.223333333 175 132 148 171.6666667 151.6666667 0.434509202 -0.19731951 05231///Choline metabolism in cancer GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0015220///choline transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0090422///thiamine pyrophosphate transmembrane transporter activity GO:0008292///acetylcholine biosynthetic process+++GO:0015871///choline transport+++GO:0030307///positive regulation of cell growth+++GO:0030974///thiamine pyrophosphate transmembrane transport+++GO:0032475///otolith formation+++GO:0035675///neuromast hair cell development+++GO:0055085///transmembrane transport+++GO:0061526///acetylcholine secretion 70134 70134 'Misp3' mRNA 74 54 71 5.35 3.87 5.45 3.28 3.5 3.27 4.89 3.35 52 54 50 66.33333333 52 0.331032516 -0.366373865 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70144 70144 'Lrch3' mRNA 2187.17 2319.93 2233.23 16.24 17.17 17.6 9.21 9.77 10.1 17.00333333 9.693333333 1269.39 1341.29 1364.95 2246.776667 1325.21 1.10E-23 -0.773493002 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032185///septin cytoskeleton organization 70152 70152 'Mettl7a1' mRNA 266.61 272.78 230.78 7.8 7.93 7.18 6.14 5.52 5.69 7.636666667 5.783333333 238.88 210.98 215.88 256.7233333 221.9133333 0.223049159 -0.22214565 GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0032259///methylation 70153 70153 '2210016F16Rik' mRNA 842 874 853 16.46 16.82 17.69 22.89 24.31 22.94 16.99 23.38 1347 1397 1307 856.3333333 1350.333333 1.25E-13 0.645276948 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006400///tRNA modification+++GO:0101030///tRNA-guanine transglycosylation 70155 70155 'Ogfrl1' mRNA 112 105 115 1.24 1.15 1.35 1.73 1.68 1.98 1.246666667 1.796666667 180 171 200 110.6666667 183.6666667 7.23E-04 0.717389257 GO:0005575///cellular_component+++GO:0016020///membrane GO:0004985///opioid receptor activity+++GO:0038023///signaling receptor activity GO:0008150///biological_process 70160 70160 'Vps36' mRNA 738 721 763 10.94 10.51 11.99 15.62 17.86 15.54 11.14666667 16.34 1213 1355 1169 740.6666667 1245.666667 3.57E-13 0.737469326 04144///Endocytosis GO:0000814///ESCRT II complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031902///late endosome membrane GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0043130///ubiquitin binding GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 70178 70178 'Abhd17c' mRNA 122 119 85 3.07 2.95 2.27 3.5 2.8 3 2.763333333 3.1 160 125 133 108.6666667 139.3333333 0.174649267 0.350832588 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055038///recycling endosome membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity GO:0002084///protein depalmitoylation+++GO:0099175///regulation of postsynapse organization+++GO:1902817///negative regulation of protein localization to microtubule+++GO:1905668///positive regulation of protein localization to endosome 70186 70186 'Fam162a' mRNA 795 743 744 84.35 78.32 83.78 90.9 87.9 92.7 82.15 90.5 979 921 963 760.6666667 954.3333333 0.001102704 0.315003072 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:0090200///positive regulation of release of cytochrome c from mitochondria 70192 70192 'Cd209g' mRNA 15.21 5.51 5.77 0.88 0.31 0.35 0.07 0.11 0.31 0.513333333 0.163333333 1.38 2.18 5.96 8.83 3.173333333 0.196356322 -1.64190407 04145///Phagosome+++04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++05162///Measles GO:0005575///cellular_component+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0030246///carbohydrate binding+++GO:0048306///calcium-dependent protein binding GO:0044419///interspecies interaction between organisms+++GO:0046718///viral entry into host cell 70207 70207 'Taco1' mRNA 116 99 111 4.07 3.66 4.29 4.7 4.99 4.84 4.006666667 4.843333333 150 150 152 108.6666667 150.6666667 0.048505816 0.458330218 GO:0005739///mitochondrion GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019843///rRNA binding+++GO:0097177///mitochondrial ribosome binding GO:0006417///regulation of translation+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0061743///motor learning+++GO:0070129///regulation of mitochondrial translation+++GO:1904959///regulation of cytochrome-c oxidase activity 70208 70208 'Med23' mRNA 617 645 654 6.68 6.86 7.51 5.73 4.73 5.53 7.016666667 5.33 609 491 570 638.6666667 556.6666667 0.097348274 -0.2129683 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex GO:0061630///ubiquitin protein ligase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:2000409///positive regulation of T cell extravasation" 70209 70209 'Tmem143' mRNA 128 132 107 3.41 3.44 2.97 2.05 1.78 2.2 3.273333333 2.01 90 76 94 122.3333333 86.66666667 0.049392108 -0.506442145 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 70218 70218 'Kif18b' mRNA 0 1 3 0 0.02 0.05 1.54 1.59 1.5 0.023333333 1.543333333 110 109 103 1.333333333 107.3333333 2.96E-15 6.316634221 GO:0000235///astral microtubule+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0016604///nuclear body+++GO:0035371///microtubule plus-end+++GO:0061673///mitotic spindle astral microtubule+++GO:1990023///mitotic spindle midzone+++GO:1990752///microtubule end "GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0016887///ATPase activity+++GO:0019894///kinesin binding+++GO:1990939///ATP-dependent microtubule motor activity" GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0007018///microtubule-based movement+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0051302///regulation of cell division 70223 70223 'Nars' mRNA 2942 3275 3171 62.87 68.89 71.88 65.76 70.83 66.06 67.88 67.55 3540 3722 3443 3129.333333 3568.333333 0.024363626 0.17708676 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004816///asparagine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0031728///CCR3 chemokine receptor binding+++GO:0046983///protein dimerization activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006421///asparaginyl-tRNA aminoacylation+++GO:0016477///cell migration+++GO:0021987///cerebral cortex development 70225 70225 'Ppil3' mRNA 357.63 358.24 337.75 22.62 21.45 22.51 28.35 25.16 29.52 22.19333333 27.67666667 532.91 468.34 531.05 351.2066667 510.7666667 2.67E-05 0.5294587 GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006457///protein folding+++GO:0008380///RNA splicing 70227 70227 'Zfp619' mRNA 89 90 89 0.76 0.76 0.78 0.58 0.43 0.5 0.766666667 0.503333333 80 60 64 89.33333333 68 0.18746087 -0.408101071 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II" 70231 70231 'Gorasp2' mRNA 4940 5185 5055 121.26 125.35 131.63 106.69 107.38 103.02 126.08 105.6966667 5002 4911 4672 5060 4861.666667 0.332754862 -0.070341339 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0016020///membrane GO:0003674///molecular_function GO:0006996///organelle organization+++GO:0007030///Golgi organization+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0061951///establishment of protein localization to plasma membrane+++GO:0070925///organelle assembly 70233 70233 'Cd2bp2' mRNA 1292 1284 1338 23.34 22.67 25.64 23.06 20.59 23.76 23.88333333 22.47 1484 1292 1483 1304.666667 1419.666667 0.29964108 0.107501553 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005682///U5 snRNP+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0043021///ribonucleoprotein complex binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity 70235 70235 'Poc1a' mRNA 57 76.96 84.91 1.2 1.76 2.15 3.58 3.98 4.17 1.703333333 3.91 149.68 171.29 165 72.95666667 161.99 4.27E-06 1.145620108 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003431///growth plate cartilage chondrocyte development+++GO:0007052///mitotic spindle organization+++GO:0007283///spermatogenesis+++GO:0010825///positive regulation of centrosome duplication+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:0060348///bone development+++GO:1905515///non-motile cilium assembly 70237 70237 'Bhlhb9' mRNA 1246 1133 1178 22.98 20.64 23.41 12.73 12.07 11.97 22.34333333 12.25666667 764 706 696 1185.666667 722 6.41E-15 -0.728881013 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0042803///protein homodimerization activity GO:0007611///learning or memory+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050769///positive regulation of neurogenesis+++GO:0051965///positive regulation of synapse assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis 70238 70238 'Rnf168' mRNA 609.32 663.95 636.26 7.32 7.85 8.11 8.19 7.83 7.4 7.76 7.806666667 784.86 732.75 686.43 636.51 734.68 0.094214995 0.193924863 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0035861///site of double-strand break+++GO:1990391///DNA repair complex GO:0003682///chromatin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031491///nucleosome binding+++GO:0042393///histone binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0033522///histone H2A ubiquitination+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0034644///cellular response to UV+++GO:0035518///histone H2A monoubiquitination+++GO:0036351///histone H2A-K13 ubiquitination+++GO:0036352///histone H2A-K15 ubiquitination+++GO:0045190///isotype switching+++GO:0045739///positive regulation of DNA repair+++GO:0070534///protein K63-linked ubiquitination+++GO:0070535///histone H2A K63-linked ubiquitination+++GO:1903827///regulation of cellular protein localization 70239 70239 'Gtf3c5' mRNA 994 1018 958 20.38 20.49 20.54 13.33 13.84 14.31 20.47 13.82666667 747 763 786 990 765.3333333 4.45E-05 -0.382302409 GO:0000127///transcription factor TFIIIC complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0035914///skeletal muscle cell differentiation 70240 70240 'Ufsp1' mRNA 161 178 153 10.34 11.31 10.43 6.84 7.3 8.47 10.69333333 7.536666667 122 127 146 164 131.6666667 0.151306157 -0.326086267 GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0071567///UFM1 hydrolase activity GO:0006508///proteolysis 70247 70247 'Psmd1' mRNA 3191 3464 3451 53.54 57.18 61.42 60.78 58.08 61.94 57.38 60.26666667 4169 3891 4114 3368.666667 4058 3.51E-04 0.254839833 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05169///Epstein-Barr virus infection "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0022624///proteasome accessory complex+++GO:0034515///proteasome storage granule" GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0031625///ubiquitin protein ligase binding GO:0042176///regulation of protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0050790///regulation of catalytic activity 70248 70248 'Dazap1' mRNA 310 355 138 8.61 9.83 4.09 7.23 5.99 6.77 7.51 6.663333333 292 241 270 267.6666667 267.6666667 0.996507085 0.004285698 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0032991///protein-containing complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008266///poly(U) RNA binding+++GO:0034046///poly(G) binding+++GO:0035613///RNA stem-loop binding "GO:0001893///maternal placenta development+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 70257 70257 'Atp5mpl' mRNA 2348 2138 2725 590.9 542.77 731.39 474.64 499.83 533.16 621.6866667 502.5433333 2135 2171 2299 2403.666667 2201.666667 0.222564411 -0.144353098 GO:0005739///mitochondrion+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process 70261 70261 'Chp2' mRNA 78 77 56 3.27 3.23 2.35 2.76 2.35 2.28 2.95 2.463333333 79 73 62 70.33333333 71.33333333 0.978276716 0.013331201 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0008284///positive regulation of cell proliferation+++GO:0010922///positive regulation of phosphatase activity+++GO:0015031///protein transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0071277///cellular response to calcium ion 70266 70266 'Kyat1' mRNA 809 910 836 23.67 25.73 25.99 9.59 10.92 11.35 25.13 10.62 383 422 442 851.6666667 415.6666667 1.35E-20 -1.045425131 00270///Cysteine and methionine metabolism+++00380///Tryptophan metabolism+++00450///Selenocompound metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042803///protein homodimerization activity+++GO:0047316///glutamine-phenylpyruvate transaminase activity+++GO:0047804///cysteine-S-conjugate beta-lyase activity+++GO:0070548///L-glutamine aminotransferase activity GO:0006090///pyruvate metabolic process+++GO:0006575///cellular modified amino acid metabolic process+++GO:0009058///biosynthetic process+++GO:0009617///response to bacterium+++GO:0070189///kynurenine metabolic process+++GO:0097052///L-kynurenine metabolic process+++GO:0097053///L-kynurenine catabolic process 70274 70274 'Ly6g6e' mRNA 193 214 188 11.39 12.17 11.5 15.25 18.64 16.85 11.68666667 16.91333333 298 360 324 198.3333333 327.3333333 1.39E-05 0.714077012 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0045202///synapse GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0030549///acetylcholine receptor activator activity+++GO:0033130///acetylcholine receptor binding GO:0002029///desensitization of G protein-coupled receptor signaling pathway+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0095500///acetylcholine receptor signaling pathway 70285 70285 'Rpf1' mRNA 541 559 590 24.34 24.78 28.36 28.1 27.76 27.88 25.82666667 27.91333333 710 679 682 563.3333333 690.3333333 0.016789018 0.27920083 "GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor" GO:0003723///RNA binding+++GO:0019843///rRNA binding+++GO:0042134///rRNA primary transcript binding GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 70291 70291 'Mkrn2os' mRNA 2347 2229 2136 51.43 48.09 49.66 5.98 5.91 5 49.72666667 5.63 314 303 254 2237.333333 290.3333333 5.53E-216 -2.95764459 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70292 70292 'Afap1' mRNA 2540 2549 2471 20.24 20.02 20.86 18.14 16.58 17.07 20.37333333 17.26333333 2611 2333 2383 2520 2442.333333 0.488325231 -0.057989944 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton GO:0003779///actin binding+++GO:0017124///SH3 domain binding+++GO:0042169///SH2 domain binding GO:0009966///regulation of signal transduction+++GO:0051493///regulation of cytoskeleton organization 70294 70294 'Rnf126' mRNA 445.91 408.02 332.33 8.9 9.13 7.32 7.07 6.49 8.71 8.45 7.423333333 328.28 311.41 358.02 395.42 332.57 0.101398349 -0.256734816 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0071629///cytoplasm protein quality control by the ubiquitin-proteasome system" 70296 70296 'Tbc1d13' mRNA 216 170 179 3.07 2.36 2.7 2.91 2.98 2.96 2.71 2.95 233 233 229 188.3333333 231.6666667 0.143798347 0.287386064 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 70297 70297 'Gcc2' mRNA 902 882 968 7.3 7.02 8.31 5.98 5.92 6.14 7.543333333 6.013333333 850 824 847 917.3333333 840.3333333 0.219759295 -0.14106047 05132///Salmonella infection GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0006622///protein targeting to lysosome+++GO:0015031///protein transport+++GO:0031023///microtubule organizing center organization+++GO:0034067///protein localization to Golgi apparatus+++GO:0034453///microtubule anchoring+++GO:0034499///late endosome to Golgi transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0070861///regulation of protein exit from endoplasmic reticulum+++GO:0071955///recycling endosome to Golgi transport+++GO:0090161///Golgi ribbon formation" 70300 70300 'Fuz' mRNA 2019.74 1823.89 1623.58 68.42 60.82 58.19 27.91 24.69 26.39 62.47666667 26.33 947.82 816.85 871.73 1822.403333 878.8 3.44E-34 -1.063095433 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0005515///protein binding GO:0001736///establishment of planar polarity+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0003279///cardiac septum development+++GO:0007275///multicellular organism development+++GO:0008285///negative regulation of cell proliferation+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009952///anterior/posterior pattern specification+++GO:0010172///embryonic body morphogenesis+++GO:0010954///positive regulation of protein processing+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0021510///spinal cord development+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0030030///cell projection organization+++GO:0030336///negative regulation of cell migration+++GO:0035904///aorta development+++GO:0042733///embryonic digit morphogenesis+++GO:0043587///tongue morphogenesis+++GO:0045724///positive regulation of cilium assembly+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0060021///roof of mouth development+++GO:0060271///cilium assembly+++GO:0060976///coronary vasculature development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090301///negative regulation of neural crest formation+++GO:1905515///non-motile cilium assembly+++GO:2000314///negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation 70310 70310 'Plscr3' mRNA 1334.11 1258.38 1152.87 33.44 31.28 31.75 43.51 43.84 38.44 32.15666667 41.93 1789.31 1756.94 1521.68 1248.453333 1689.31 1.13E-06 0.425856544 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0000287///magnesium ion binding+++GO:0005509///calcium ion binding+++GO:0017124///SH3 domain binding+++GO:0017128///phospholipid scramblase activity+++GO:0032791///lead ion binding+++GO:0043621///protein self-association+++GO:0045340///mercury ion binding+++GO:0048306///calcium-dependent protein binding GO:0006915///apoptotic process+++GO:0017121///phospholipid scrambling+++GO:0032049///cardiolipin biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0042981///regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0090199///regulation of release of cytochrome c from mitochondria 70312 70312 'Cactin' mRNA 804 878 650 16.33 17.55 14 12.66 14.93 15.94 15.96 14.51 717 826 874 777.3333333 805.6666667 0.775375801 0.046780673 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome "GO:0001933///negative regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0006397///mRNA processing+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0010468///regulation of gene expression+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032688///negative regulation of interferon-beta production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0045824///negative regulation of innate immune response+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor" 70314 70314 'Rabep2' mRNA 935 945 939 20.25 20.14 21.59 17.09 19.16 17.09 20.66 17.78 905 992 880 939.6666667 925.6666667 0.80995528 -0.033325039 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0005096///GTPase activator activity+++GO:0008083///growth factor activity GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1902017///regulation of cilium assembly 70315 70315 'Hdac8' mRNA 738.47 669.59 655.78 10.89 10.44 9.92 8.01 7.19 7.57 10.41666667 7.59 536.23 435.25 511.8 687.9466667 494.4266667 3.24E-05 -0.489122569 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0003682///chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0030544///Hsp70 protein binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding GO:0006325///chromatin organization+++GO:0007062///sister chromatid cohesion+++GO:0010629///negative regulation of gene expression+++GO:0016575///histone deacetylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032204///regulation of telomere maintenance+++GO:0035984///cellular response to trichostatin A+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0071922///regulation of cohesin loading+++GO:1903496///response to 11-deoxycorticosterone+++GO:1904322///cellular response to forskolin+++GO:2000616///negative regulation of histone H3-K9 acetylation 70316 70316 'Ndufab1' mRNA 2029 1858 1989 219.07 198.55 224.76 224.44 257.95 224.46 214.1266667 235.6166667 2435 2642 2298.45 1958.666667 2458.483333 3.04E-04 0.315042986 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0070469///respiratory chain GO:0000035///acyl binding+++GO:0000036///acyl carrier activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0009249///protein lipoylation+++GO:0032981///mitochondrial respiratory chain complex I assembly 70317 70317 'Arl16' mRNA 395.7 400.99 422.01 11.12 11.1 12.58 10.2 11.57 10.94 11.6 10.90333333 417.03 462 433.01 406.2333333 437.3466667 0.568057237 0.095715187 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0008150///biological_process 70325 70325 'Pigw' mRNA 15 18 17 0.37 0.42 0.42 0.65 0.53 0.78 0.403333333 0.653333333 30 28 36 16.66666667 31.33333333 0.095393117 0.898584662 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0032216///glucosaminyl-phosphotidylinositol O-acyltransferase activity" GO:0006506///GPI anchor biosynthetic process+++GO:0072659///protein localization to plasma membrane 70333 70333 'Cd3eap' mRNA 340 336 315 8.51 8.28 8.36 7.59 7.89 7.4 8.383333333 7.626666667 349 354 329 330.3333333 344 0.804603501 0.047652216 03020///RNA polymerase GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0005515///protein binding GO:0006360///transcription by RNA polymerase I+++GO:0009303///rRNA transcription 70335 70335 'Reep6' mRNA 297 305 305 8.63 8.72 9.44 2.98 3.8 2.99 8.93 3.256666667 116 146 113 302.3333333 125 1.39E-12 -1.285464884 GO:0001917///photoreceptor inner segment+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044317///rod spherule+++GO:0045177///apical part of cell GO:0005515///protein binding GO:0032386///regulation of intracellular transport+++GO:0050908///detection of light stimulus involved in visual perception 70337 70337 'Iyd' mRNA 0 0 1 0 0 0.04 0.03 0.03 0 0.013333333 0.02 1 1 0 0.333333333 0.666666667 0.863090843 0.881266102 04918///Thyroid hormone synthesis GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0004447///iodide peroxidase activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity GO:0006570///tyrosine metabolic process+++GO:0042403///thyroid hormone metabolic process 70348 70348 'Ube2cbp' mRNA 46 58 63 1.53 1.8 2.1 1.01 1.15 0.85 1.81 1.003333333 35 41 29 55.66666667 35 0.091757947 -0.684648572 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016740///transferase activity+++GO:0030332///cyclin binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination 70349 70349 'Copb1' mRNA 2247 2271 2433 36.99 36.78 42.48 43.58 40.78 40.83 38.75 41.73 3047 2785 2764 2317 2865.333333 2.82E-04 0.29118737 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0030137///COPI-coated vesicle+++GO:0030663///COPI-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005198///structural molecule activity GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 70350 70350 'Basp1' mRNA 15 18 9 0.46 0.55 0.3 3.58 3.31 2.76 0.436666667 3.216666667 133 120 99 14 117.3333333 3.82E-17 3.060572892 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0042995///cell projection GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding "GO:0045892///negative regulation of transcription, DNA-templated+++GO:0072112///glomerular visceral epithelial cell differentiation" 70351 70351 'Ppp4r1' mRNA 1044.09 996.62 961.48 10.73 9.67 10.35 10.89 11.08 10.96 10.25 10.97666667 1254.62 1123.2 1206.25 1000.73 1194.69 0.006453259 0.243681882 GO:0005575///cellular_component+++GO:0008287///protein serine/threonine phosphatase complex+++GO:0030289///protein phosphatase 4 complex GO:0003674///molecular_function+++GO:0019888///protein phosphatase regulator activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 70354 70354 'Secisbp2l' mRNA 4634 4589 4054 36.27 35.27 33.66 26.87 22.84 25.06 35.06666667 24.92333333 3960 3295 3572 4425.666667 3609 7.88E-06 -0.305447525 GO:1990904///ribonucleoprotein complex GO:0003730///mRNA 3'-UTR binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding GO:0001514///selenocysteine incorporation 70355 70355 'Gprc5c' mRNA 1492 1523 1500 24.64 24.19 26.38 23.65 21.14 20.77 25.07 21.85333333 1576 1410 1348 1505 1444.666667 0.478817443 -0.072474582 GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0070062///extracellular exosome GO:0004930///G protein-coupled receptor activity+++GO:0005118///sevenless binding+++GO:0030295///protein kinase activator activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007601///visual perception+++GO:0032147///activation of protein kinase activity 70356 70356 'St13' mRNA 4222 4235 4331 85.47 81.95 89.97 84.03 83.96 85.91 85.79666667 84.63333333 4573 4477 4518 4262.666667 4522.666667 0.337052545 0.072103556 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex GO:0019904///protein domain specific binding+++GO:0030544///Hsp70 protein binding+++GO:0031072///heat shock protein binding+++GO:0032564///dATP binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0046983///protein dimerization activity+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding GO:0009617///response to bacterium+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0061084///negative regulation of protein refolding+++GO:0065003///protein-containing complex assembly 70357 70357 'Kcnip1' mRNA 1 8 0 0.04 0.24 0 0.08 0.07 0.12 0.093333333 0.09 4 2 4 3 3.333333333 0.932123331 0.173998605 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0034705///potassium channel complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005509///calcium ion binding+++GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0045760///positive regulation of action potential+++GO:0071805///potassium ion transmembrane transport+++GO:1901379///regulation of potassium ion transmembrane transport 70358 70358 'Steap1' mRNA 35 33 38 1.76 1.64 2.03 2.41 1.76 2.18 1.81 2.116666667 55 39 48 35.33333333 47.33333333 0.365827184 0.40477102 04978///Mineral absorption GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008823///cupric reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016723///oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor+++GO:0046872///metal ion binding+++GO:0052851///ferric-chelate reductase (NADPH) activity" GO:0006811///ion transport+++GO:0015677///copper ion import+++GO:0055072///iron ion homeostasis+++GO:0098706///ferric iron import across cell outer membrane 70359 70359 'Gtpbp3' mRNA 397.83 387.81 329.59 10.04 9.79 8.47 8.53 8.06 8.43 9.433333333 8.34 389.17 356.3 373.53 371.7433333 373 0.993775473 -0.003003467 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0002098///tRNA wobble uridine modification+++GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation 70361 70361 'Lman1' mRNA 2160 2305 2275 37.64 39.16 42.24 41.63 44.88 41.67 39.68 42.72666667 2658 2744 2506 2246.666667 2636 0.005695525 0.217986223 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030017///sarcomere+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0010638///positive regulation of organelle organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 70362 70362 'Actl10' mRNA 10 3 9 0.39 0.12 0.38 0.07 0 0.11 0.296666667 0.06 2 0 3 7.333333333 1.666666667 0.128178746 -2.165765388 GO:0005869///dynactin complex GO:0003674///molecular_function GO:0008150///biological_process 70363 70363 'Fam135b' mRNA 20 18 9 0.07 0.09 0.04 0.01 0 0.01 0.066666667 0.006666667 4 0 3 15.66666667 2.333333333 0.00687085 -2.753017786 GO:0005575///cellular_component GO:0044255///cellular lipid metabolic process 70369 70369 'Bag5' mRNA 1453 1440.97 1385.96 38.36 37.45 38.88 28.7 30.91 30.72 38.23 30.11 1247.93 1315.98 1293.96 1426.643333 1285.956667 0.065361977 -0.161168796 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016234///inclusion body+++GO:0048471///perinuclear region of cytoplasm GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding GO:0007030///Golgi organization+++GO:0010977///negative regulation of neuron projection development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0050821///protein stabilization+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0061084///negative regulation of protein refolding+++GO:0070997///neuron death+++GO:0090083///regulation of inclusion body assembly+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 70370 70370 'Fbln7' mRNA 70 74 83 1.32 1.38 1.67 0.87 1.33 1.48 1.456666667 1.226666667 53 79 87 75.66666667 73 0.872838071 -0.063591912 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0043395///heparan sulfate proteoglycan binding GO:0007155///cell adhesion 70373 70373 'Gpatch2l' mRNA 694 759.11 710.91 7.69 8.74 8.75 7.66 6.54 6.93 8.393333333 7.043333333 776 637 698 721.34 703.6666667 0.743984844 -0.048336228 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70375 70375 'Ica1l' mRNA 693 617 586 11.52 10.38 10.16 0.74 0.94 1.14 10.68666667 0.94 58 63 69 632 63.33333333 1.12E-90 -3.328862389 GO:0001669///acrosomal vesicle+++GO:0005794///Golgi apparatus GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0007286///spermatid development+++GO:0051049///regulation of transport 70377 70377 'Derl3' mRNA 91 137 119 4.18 6.15 5.69 3.34 2.86 4.02 5.34 3.406666667 85 71 98 115.6666667 84.66666667 0.112870627 -0.463070177 04141///Protein processing in endoplasmic reticulum GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005047///signal recognition particle binding+++GO:0044877///protein-containing complex binding+++GO:0051787///misfolded protein binding+++GO:1990381///ubiquitin-specific protease binding "GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol" 70380 70380 'Mospd1' mRNA 466 534 465 11.63 13.07 12.28 13.65 14.44 13.48 12.32666667 13.85666667 628 649 599 488.3333333 625.3333333 0.003385182 0.346565904 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 70381 70381 'Tecpr1' mRNA 1379 1492 1472 14.36 15.33 16.3 14.95 15.72 15.16 15.33 15.27666667 1647 1691 1618 1447.666667 1652 0.04409437 0.177917264 05131///Shigellosis GO:0000421///autophagosome membrane+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding GO:0006914///autophagy+++GO:0097352///autophagosome maturation 70382 70382 'Kctd2' mRNA 181 179 152 6.04 5.81 5.36 5.07 5.35 5.53 5.736666667 5.316666667 173 180 186 170.6666667 179.6666667 0.801684748 0.065633313 GO:0005737///cytoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0044877///protein-containing complex binding+++GO:0097602///cullin family protein binding GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051260///protein homooligomerization 70383 70383 'Cox10' mRNA 374 431 370 7.05 7.99 7.39 7.19 7.23 6.38 7.476666667 6.933333333 439 431 377 391.6666667 415.6666667 0.668579239 0.07527496 00190///Oxidative phosphorylation+++00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors+++04714///Thermogenesis GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0070069///cytochrome complex "GO:0004129///cytochrome-c oxidase activity+++GO:0004311///farnesyltranstransferase activity+++GO:0008495///protoheme IX farnesyltransferase activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups" GO:0000266///mitochondrial fission+++GO:0006783///heme biosynthetic process+++GO:0006784///heme a biosynthetic process+++GO:0007005///mitochondrion organization+++GO:0008535///respiratory chain complex IV assembly+++GO:0009060///aerobic respiration+++GO:0017004///cytochrome complex assembly+++GO:0018343///protein farnesylation+++GO:0022900///electron transport chain+++GO:0045333///cellular respiration+++GO:0048034///heme O biosynthetic process+++GO:1902600///proton transmembrane transport 70385 70385 'Spdl1' mRNA 24 28 38 0.53 0.6 0.85 3.46 2.68 2.86 0.66 3 183 136 144 30 154.3333333 1.52E-15 2.342870017 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:0000940///condensed chromosome outer kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton" GO:0019899///enzyme binding+++GO:0043515///kinetochore binding GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0016477///cell migration+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division 70387 70387 'Ttc9c' mRNA 839 895 860 13.43 13.98 14.52 12.24 12.08 11.72 13.97666667 12.01333333 886 855 829 864.6666667 856.6666667 0.857024457 -0.025751713 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70394 70394 'Kptn' mRNA 479 562 527 16.93 19.59 19.76 14.67 13.43 11.03 18.76 13.04333333 477 426 347 522.6666667 416.6666667 0.021714125 -0.340760876 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0031941///filamentous actin+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0140007///KICSTOR complex GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0034198///cellular response to amino acid starvation+++GO:0042149///cellular response to glucose starvation+++GO:0061462///protein localization to lysosome+++GO:1904262///negative regulation of TORC1 signaling 70396 70396 'Asnsd1' mRNA 687 762 755 17.35 19.15 20.63 15.74 16.19 17.09 19.04333333 16.34 679 718 734 734.6666667 710.3333333 0.671660644 -0.061012987 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0004066///asparagine synthase (glutamine-hydrolyzing) activity GO:0006529///asparagine biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0008150///biological_process 70397 70397 'Tmem70' mRNA 907 968 846 30.37 31.96 30.05 30.12 29.8 30.02 30.79333333 29.98 1034 998 997 907 1009.666667 0.137210212 0.144450723 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032592///integral component of mitochondrial membrane GO:0003674///molecular_function GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly 70408 70408 'Polr3f' mRNA 487 484 534 6.31 6.16 7.34 4.57 4.35 4.88 6.603333333 4.6 406 378 420 501.6666667 401.3333333 0.013550054 -0.336870476 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex GO:0003690///double-stranded DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus 70415 70415 'Stk26' mRNA 27 21.94 25 0.44 0.36 0.44 0.67 0.36 0.32 0.413333333 0.45 47 24.87 22 24.64666667 31.29 0.602094966 0.328767105 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0009267///cellular response to starvation+++GO:0016310///phosphorylation+++GO:0030033///microvillus assembly+++GO:0030336///negative regulation of cell migration+++GO:0042542///response to hydrogen peroxide+++GO:0042981///regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:1903205///regulation of hydrogen peroxide-induced cell death 70417 70417 'Megf10' mRNA 972 957 896 6.82 6.6 6.67 3.4 3.06 3.68 6.696666667 3.38 559 491 586 941.6666667 545.3333333 3.73E-15 -0.799631814 GO:0001891///phagocytic cup+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0001849///complement component C1q binding+++GO:0005044///scavenger receptor activity+++GO:0005112///Notch binding GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0007517///muscle organ development+++GO:0014719///skeletal muscle satellite cell activation+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0014841///skeletal muscle satellite cell proliferation+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0033002///muscle cell proliferation+++GO:0034109///homotypic cell-cell adhesion+++GO:0043277///apoptotic cell clearance+++GO:0043652///engulfment of apoptotic cell+++GO:0043654///recognition of apoptotic cell+++GO:0048627///myoblast development+++GO:0048641///regulation of skeletal muscle tissue development+++GO:0051147///regulation of muscle cell differentiation+++GO:0051451///myoblast migration+++GO:0055001///muscle cell development+++GO:1902742///apoptotic process involved in development+++GO:2000288///positive regulation of myoblast proliferation 70419 70419 '2810408A11Rik' mRNA 93 125 105 3.17 4.29 3.89 1.24 1.38 1.77 3.783333333 1.463333333 43 46 56 107.6666667 48.33333333 7.40E-05 -1.165364335 GO:0004864///protein phosphatase inhibitor activity GO:0009966///regulation of signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0043666///regulation of phosphoprotein phosphatase activity 70420 70420 'Arpin' mRNA 614 631 542 15.86 16.05 14.85 18.35 18.73 17.75 15.58666667 18.27666667 817 814 765 595.6666667 798.6666667 5.61E-05 0.413592741 GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030336///negative regulation of cell migration+++GO:0033058///directional locomotion+++GO:0051126///negative regulation of actin nucleation+++GO:2000393///negative regulation of lamellipodium morphogenesis 70422 70422 'Ints2' mRNA 484.15 491.78 429.81 3.92 3.87 3.72 4.44 4.13 4.56 3.836666667 4.376666667 612.93 563.75 613.75 468.58 596.81 0.003613535 0.338621609 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing 70423 70423 'Tspan15' mRNA 5525.71 5422.1 1754.68 132.09 129.53 36.74 28.43 48.13 44.33 99.45333333 40.29666667 1345.2 2058.91 1964.96 4234.163333 1789.69 0.027974798 -1.226906528 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097197///tetraspanin-enriched microdomain GO:0019899///enzyme binding GO:0045746///negative regulation of Notch signaling pathway+++GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane 70425 70425 'Csnk1g3' mRNA 477 416 344 5.88 5.08 4.54 4.26 4.01 4.5 5.166666667 4.256666667 394 362 405 412.3333333 387 0.576233912 -0.099287934 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006897///endocytosis+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway 70426 70426 'Tekt5' mRNA 34 40 52 1.11 1.29 1.81 1.57 2.16 1.94 1.403333333 1.89 55 74 66 42 65 0.112206955 0.613734963 GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility 70427 70427 'Mier2' mRNA 866.33 861.55 824.58 14.77 15.44 15.03 10.88 9.49 11.21 15.08 10.52666667 653.28 566.08 645.7 850.82 621.6866667 5.00E-06 -0.465000695 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation 70428 70428 'Polr3b' mRNA 447 478 470 4.81 5.05 5.36 5.1 4.57 5.3 5.073333333 4.99 546 478 550 465 524.6666667 0.246120803 0.160839765 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0032549///ribonucleoside binding+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0006351///transcription, DNA-templated+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus" 70430 70430 'Tbce' mRNA 405.18 519.4 494 11.88 15.06 15.68 13.39 12.72 13.82 14.20666667 13.31 524.76 487.81 515.76 472.86 509.4433333 0.585654441 0.092187934 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0043014///alpha-tubulin binding+++GO:0051082///unfolded protein binding GO:0000226///microtubule cytoskeleton organization+++GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007023///post-chaperonin tubulin folding pathway+++GO:0007052///mitotic spindle organization+++GO:0007409///axonogenesis+++GO:0008344///adult locomotory behavior+++GO:0009791///post-embryonic development+++GO:0014889///muscle atrophy+++GO:0048589///developmental growth+++GO:0048936///peripheral nervous system neuron axonogenesis 70432 70432 'Rufy2' mRNA 745.47 791.04 725.84 5.57 5.85 5.68 4.57 3.86 3.93 5.7 4.12 692.91 566.93 572.49 754.1166667 610.7766667 0.004998414 -0.317891229 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding 70433 70433 'Draxin' mRNA 86 112 113 0.88 1.13 1.23 0.35 0.36 0.3 1.08 0.336666667 39 40 33 103.6666667 37.33333333 1.54E-06 -1.488242671 GO:0005576///extracellular region GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0010977///negative regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0021516///dorsal spinal cord development+++GO:0021528///commissural neuron differentiation in spinal cord+++GO:0021960///anterior commissure morphogenesis+++GO:0030517///negative regulation of axon extension+++GO:0030900///forebrain development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway 70435 70435 'Inf2' mRNA 896.68 956.05 811.86 9.46 9.55 9.52 12.32 12.82 11.33 9.51 12.15666667 1269.69 1258.05 1192.94 888.1966667 1240.226667 5.09E-08 0.472364841 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0003779///actin binding+++GO:0031267///small GTPase binding GO:0016043///cellular component organization+++GO:0030036///actin cytoskeleton organization+++GO:0032535///regulation of cellular component size+++GO:0090140///regulation of mitochondrial fission 70439 70439 'Taf15' mRNA 150 132 95 3.59 3.21 2.47 2.81 1.31 2.12 3.09 2.08 129 63 98 125.6666667 96.66666667 0.22521685 -0.388516895 03022///Basal transcription factors+++05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003712///transcription coregulator activity+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0010467///gene expression+++GO:0048255///mRNA stabilization" 70445 70445 'Cd248' mRNA 141 145 119 3.06 3.1 2.74 5.64 6.12 6.31 2.966666667 6.023333333 299 317 324 135 313.3333333 8.18E-13 1.20659129 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0030246///carbohydrate binding+++GO:0050840///extracellular matrix binding+++GO:1990430///extracellular matrix protein binding GO:0008284///positive regulation of cell proliferation+++GO:0016477///cell migration+++GO:0048535///lymph node development+++GO:0060033///anatomical structure regression+++GO:2000353///positive regulation of endothelial cell apoptotic process 70450 70450 'Unc13d' mRNA 109 86 75 1.38 1.07 1.05 3.81 3.38 3.16 1.166666667 3.45 336 287 271 90 298 1.16E-18 1.7173921 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0033093///Weibel-Palade body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:0070382///exocytic vesicle GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0001944///vasculature development+++GO:0002432///granuloma formation+++GO:0002467///germinal center formation+++GO:0006887///exocytosis+++GO:0006909///phagocytosis+++GO:0043304///regulation of mast cell degranulation+++GO:0043320///natural killer cell degranulation+++GO:0045921///positive regulation of exocytosis+++GO:0051607///defense response to virus+++GO:0060155///platelet dense granule organization+++GO:0061789///dense core granule priming+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:1903307///positive regulation of regulated secretory pathway 70451 70451 'Dhrs13' mRNA 188 194 169 6.24 6.34 5.95 5.83 4.67 4.48 6.176666667 4.993333333 202 158 150 183.6666667 170 0.619994862 -0.1235607 GO:0005576///extracellular region+++GO:0005743///mitochondrial inner membrane GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process 70454 70454 'Cenpl' mRNA 55 71 75 1.34 1.71 1.95 3.36 3.31 3.6 1.666666667 3.423333333 158 152 164 67 158 5.54E-07 1.222904937 "GO:0000775///chromosome, centromeric region+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005694///chromosome" GO:0003674///molecular_function GO:0008150///biological_process 70456 70456 'Mpc2' mRNA 1941 1867 1903 163.65 156.01 170.27 154.02 172.38 158.22 163.31 161.54 2091 2279 2074 1903.666667 2148 0.059256362 0.162336401 05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0042802///identical protein binding+++GO:0050833///pyruvate transmembrane transporter activity GO:0006850///mitochondrial pyruvate transmembrane transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate 70458 70458 '2610318N02Rik' mRNA 30 39 20 1.54 1.9 1.12 1.52 2.57 2.11 1.52 2.066666667 36 59 48 29.66666667 47.66666667 0.139265437 0.686449774 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70461 70461 'Crtc3' mRNA 1513 1395 882 15.69 14.23 9.75 8.15 10 9.34 13.22333333 9.163333333 906 1085 1003 1263.333333 998 0.022525886 -0.339655397 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008140///cAMP response element binding protein binding GO:0032793///positive regulation of CREB transcription factor activity+++GO:0042116///macrophage activation+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051289///protein homotetramerization+++GO:0071878///negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0097009///energy homeostasis 70465 70465 'Wdr77' mRNA 1040 1141 1062 15.9 17.17 17.23 18.05 17.81 17.29 16.76666667 17.71666667 1358 1309 1260 1081 1309 0.002516088 0.264203802 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0034709///methylosome+++GO:0045495///pole plasm GO:0005515///protein binding+++GO:0008327///methyl-CpG binding+++GO:0030374///nuclear receptor transcription coactivator activity "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007315///pole plasm assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060528///secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development" 70466 70466 'Ckap2l' mRNA 20 14 25 0.35 0.24 0.46 5.23 5.38 5.49 0.35 5.366666667 330 339 349 19.66666667 339.3333333 5.41E-57 4.09475777 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0008150///biological_process 70470 70470 'Rprd1b' mRNA 1066 1174 1079 15.86 17.55 17.51 12.48 12.37 12.72 16.97333333 12.52333333 960 944 944 1106.333333 949.3333333 0.011810338 -0.232192978 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016591///RNA polymerase II, holoenzyme" GO:0000993///RNA polymerase II complex binding+++GO:0042802///identical protein binding GO:0008284///positive regulation of cell proliferation+++GO:0010564///regulation of cell cycle process+++GO:0031124///mRNA 3'-end processing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain 70472 70472 'Atad2' mRNA 286.46 250.26 253.53 2.67 2.29 2.51 6.16 5.41 5.79 2.49 5.786666667 760.84 652.31 692.16 263.4166667 701.77 2.64E-30 1.402380141 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042393///histone binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031936///negative regulation of chromatin silencing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 70478 70478 'Mipep' mRNA 727 775 176 16.89 17.73 4.34 3.05 3.99 4.49 12.98666667 3.843333333 151 193 215 559.3333333 186.3333333 0.01785546 -1.567180815 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0006627///protein processing involved in protein targeting to mitochondrion 70481 70481 'Pnma1' mRNA 75 58 68 1.78 1.36 1.71 0.56 0.38 0.77 1.616666667 0.57 27 18 36 67 27 7.63E-04 -1.32630749 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0002437///inflammatory response to antigenic stimulus 70484 70484 'Slc35d2' mRNA 57.08 57 65 1.16 1.14 1.38 3.28 2.76 3.43 1.226666667 3.156666667 167.96 137.28 165.42 59.69333333 156.8866667 2.39E-08 1.373993537 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005461///UDP-glucuronic acid transmembrane transporter activity+++GO:0005462///UDP-N-acetylglucosamine transmembrane transporter activity+++GO:0005463///UDP-N-acetylgalactosamine transmembrane transporter activity+++GO:0015297///antiporter activity GO:0008643///carbohydrate transport+++GO:0015787///UDP-glucuronic acid transmembrane transport+++GO:0015789///UDP-N-acetylgalactosamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990569///UDP-N-acetylglucosamine transmembrane transport 70495 70495 'Atp6ap2' mRNA 5490 5530.99 5682 129.79 128.75 142.5 160.19 156.96 154.43 133.68 157.1933333 7793 7456 7272.99 5567.663333 7507.33 1.46E-11 0.417391271 04614///Renin-angiotensin system GO:0000421///autophagosome membrane+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0044297///cell body+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0038023///signaling receptor activity GO:0002003///angiotensin maturation+++GO:0007042///lysosomal lumen acidification+++GO:0021626///central nervous system maturation+++GO:0021903///rostrocaudal neural tube patterning+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0043408///regulation of MAPK cascade+++GO:0048069///eye pigmentation+++GO:0060323///head morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway 70497 70497 'Arhgap17' mRNA 928 996 895 14.82 15.58 15.16 15.2 15.83 16.14 15.18666667 15.72333333 1087 1114 1114 939.6666667 1105 0.015097637 0.223519961 04530///Tight junction GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0017156///calcium ion regulated exocytosis+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035020///regulation of Rac protein signal transduction+++GO:0050790///regulation of catalytic activity 70503 70503 'Ddo' mRNA 948 889 1014 20.78 19.12 23.82 7.52 6.55 7.49 21.24 7.186666667 364.37 278 362 950.3333333 334.79 4.93E-33 -1.522683639 "00250///Alanine, aspartate and glutamate metabolism+++00470///D-Amino acid metabolism+++04146///Peroxisome" GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol GO:0003884///D-amino-acid oxidase activity+++GO:0008445///D-aspartate oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0071949///FAD binding GO:0006531///aspartate metabolic process+++GO:0006533///aspartate catabolic process+++GO:0007320///insemination+++GO:0007625///grooming behavior+++GO:0019478///D-amino acid catabolic process+++GO:0042445///hormone metabolic process+++GO:0046416///D-amino acid metabolic process 70508 70508 'Bbx' mRNA 1489 1475 1405 12.52 12.44 12.99 10.14 9.4 9.96 12.65 9.833333333 1449 1263 1363 1456.333333 1358.333333 0.210515717 -0.112851751 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060348///bone development 70510 70510 'Rnf167' mRNA 4433.74 4612.85 4243.69 138.42 142.12 141.25 71.37 70.94 72.51 140.5966667 71.60666667 2648.33 2593.18 2606.47 4430.093333 2615.993333 1.13E-41 -0.770946817 GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0045786///negative regulation of cell cycle 70511 70511 'Eef2kmt' mRNA 560.59 583.45 519.64 14.81 15.18 14.56 15.85 15.43 15.13 14.85 15.47 690.07 655.91 637.4 554.56 661.1266667 0.029603954 0.243357124 GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity GO:0018023///peptidyl-lysine trimethylation+++GO:0032259///methylation 70527 70527 'Stambp' mRNA 1006 1120 1081 25.8 27.98 29.49 18.49 17.77 15.76 27.75666667 17.34 826 782 685 1069 764.3333333 1.59E-06 -0.497306501 04144///Endocytosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032154///cleavage furrow GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070122///isopeptidase activity+++GO:0101005///ubiquitinyl hydrolase activity GO:0000281///mitotic cytokinesis+++GO:0006508///proteolysis+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0016579///protein deubiquitination+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0070536///protein K63-linked deubiquitination 70530 70530 'Lrfn2' mRNA 66 28 32 1.11 0.45 0.59 0.31 0.39 0.23 0.716666667 0.31 20 30 16 42 22 0.080720754 -0.937209264 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0050804///modulation of chemical synaptic transmission+++GO:0099175///regulation of postsynapse organization 70533 70533 'Btf3l4' mRNA 1576 1656 1540 29.42 30.78 30.83 27.59 26.68 27.19 30.34333333 27.15333333 1711 1561 1621 1590.666667 1631 0.819903519 0.024194188 04214///Apoptosis - fly GO:0005575///cellular_component GO:0008150///biological_process 70536 70536 'Qpct' mRNA 1321 1456 1463 36.53 39.66 42.94 22.79 20.88 22.26 39.71 21.97666667 950 849 897 1413.333333 898.6666667 4.74E-13 -0.667615688 GO:0005576///extracellular region "GO:0008235///metalloexopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016603///glutaminyl-peptide cyclotransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" "GO:0006508///proteolysis+++GO:0017186///peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase" 70544 70544 'Tmem242' mRNA 1057 1151 976 70.11 75.52 68.69 71.12 72.79 69.35 71.44 71.08666667 1229 1226 1158 1061.333333 1204.333333 0.061278202 0.172814231 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 70546 70546 'Zdhhc2' mRNA 682.06 716.7 713.28 10.75 11.19 11.99 8.96 8.46 8.71 11.31 8.71 650.38 602.12 612.88 704.0133333 621.7933333 0.092946764 -0.192802908 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0055038///recycling endosome membrane+++GO:0098837///postsynaptic recycling endosome "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0042803///protein homodimerization activity" GO:0006612///protein targeting to membrane+++GO:0016188///synaptic vesicle maturation+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0022407///regulation of cell-cell adhesion+++GO:0042176///regulation of protein catabolic process+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0072659///protein localization to plasma membrane+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1903539///protein localization to postsynaptic membrane+++GO:1904719///positive regulation of AMPA glutamate receptor clustering+++GO:1905751///positive regulation of endosome to plasma membrane protein transport 70549 70549 'Tln2' mRNA 1804.91 1780.83 1509.75 7.65 7.41 6.78 6.2 6 6.33 7.28 6.176666667 1685.9 1596.29 1665.68 1698.496667 1649.29 0.599633518 -0.051281803 04015///Rap1 signaling pathway+++04510///Focal adhesion+++04611///Platelet activation+++05131///Shigellosis+++05166///Human T-cell leukemia virus 1 infection GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005916///fascia adherens+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0030276///clathrin binding+++GO:0051015///actin filament binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 70551 70551 'Tmtc4' mRNA 1530 1577 1428 24.2 24.62 24.09 10.12 10.83 10.42 24.30333333 10.45666667 740 774 736 1511.666667 750 5.39E-35 -1.021319627 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0051117///ATPase binding GO:0006486///protein glycosylation+++GO:0007605///sensory perception of sound+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0032470///positive regulation of endoplasmic reticulum calcium ion concentration+++GO:0035269///protein O-linked mannosylation+++GO:1905584///outer hair cell apoptotic process 70552 70552 'Lrrc56' mRNA 475 474 510 11.62 11.69 13.46 3.34 3.54 2.68 12.25666667 3.186666667 176 168 139 486.3333333 161 5.23E-26 -1.609769337 GO:0005575///cellular_component+++GO:0005929///cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030030///cell projection organization 70556 70556 'Slc25a33' mRNA 935 1074 208 32.75 37.83 8.14 7.12 6.41 10.38 26.24 7.97 216 211 325 739 250.6666667 0.034430028 -1.541255872 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0015218///pyrimidine nucleotide transmembrane transporter activity GO:0000002///mitochondrial genome maintenance+++GO:0002082///regulation of oxidative phosphorylation+++GO:0006390///mitochondrial transcription+++GO:0006864///pyrimidine nucleotide transport+++GO:0007005///mitochondrion organization+++GO:0008284///positive regulation of cell proliferation+++GO:0030307///positive regulation of cell growth+++GO:0031930///mitochondria-nucleus signaling pathway+++GO:0032869///cellular response to insulin stimulus+++GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0071156///regulation of cell cycle arrest+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:1990519///pyrimidine nucleotide import into mitochondrion 70560 70560 'Wars2' mRNA 416.82 386.98 381.17 4.73 4.27 4.61 2.39 2.28 2.36 4.536666667 2.343333333 250.75 222.51 223.92 394.99 232.3933333 5.54E-08 -0.779804265 00970///Aminoacyl-tRNA biosynthesis GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0045766///positive regulation of angiogenesis+++GO:0070183///mitochondrial tryptophanyl-tRNA aminoacylation 70561 70561 'Txndc16' mRNA 2140 2301 2184 29.76 32.43 33.2 22.1 19.52 19.11 31.79666667 20.24333333 1747 1528 1489 2208.333333 1588 5.28E-10 -0.489010302 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003674///molecular_function GO:0008150///biological_process 70564 70564 'Prxl2a' mRNA 12558 12960 12521 465.99 475.65 492.98 229.57 235.85 237.01 478.2066667 234.1433333 7112 7131 7065 12679.66667 7102.666667 2.52E-59 -0.848101066 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016209///antioxidant activity GO:0045670///regulation of osteoclast differentiation+++GO:0098869///cellular oxidant detoxification 70567 70567 'Fra10ac1' mRNA 278 339 324 11.53 14.17 14.33 10.38 10.17 9.73 13.34333333 10.09333333 280 273 252 313.6666667 268.3333333 0.171479457 -0.238416305 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0016791///phosphatase activity GO:0016311///dephosphorylation 70568 70568 'Cpne3' mRNA 1398 1508 1326 13.16 13.95 13.24 20.29 17.59 18.47 13.45 18.78333333 2482 2102 2189 1410.666667 2257.666667 3.36E-18 0.666758678 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction GO:0004674///protein serine/threonine kinase activity+++GO:0005544///calcium-dependent phospholipid binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding GO:0006468///protein phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0038128///ERBB2 signaling pathway+++GO:0071277///cellular response to calcium ion+++GO:0071363///cellular response to growth factor stimulus 70571 70571 'Tcerg1l' mRNA 38 36 13 0.82 0.77 0.3 0.13 0.1 0.1 0.63 0.11 7 5 5 29 5.666666667 7.69E-04 -2.351069342 GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0070063///RNA polymerase binding "GO:0006355///regulation of transcription, DNA-templated" 70572 70572 'Ipo5' mRNA 1275 1219 1320 15.07 14.22 16.59 16.52 14.33 16.15 15.29333333 15.66666667 1603 1370 1527 1271.333333 1500 0.020301431 0.223398598 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0031267///small GTPase binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0006610///ribosomal protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0071230///cellular response to amino acid stimulus 70573 70573 'Tbccd1' mRNA 614 657 565 11.33 12.31 11.14 8.04 9.62 9.7 11.59333333 9.12 511 560 580 612 550.3333333 0.209185254 -0.161934879 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome GO:0003674///molecular_function GO:0000902///cell morphogenesis+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0051661///maintenance of centrosome location+++GO:0051684///maintenance of Golgi location 70574 70574 'Cpm' mRNA 556 596 539 5.7 6.01 5.87 10.18 10.43 10.94 5.86 10.51666667 1145 1144 1190 563.6666667 1159.666667 3.50E-29 1.030242274 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0016485///protein processing 70575 70575 'Gfod2' mRNA 1128.81 1187.9 1083.97 12.8 13.27 13.28 7.63 7.23 7.04 13.11666667 7.3 770.25 719.17 705.62 1133.56 731.68 3.66E-13 -0.642517257 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0000166///nucleotide binding+++GO:0016491///oxidoreductase activity GO:0030198///extracellular matrix organization 70579 70579 'Zc3h11a' mRNA 2479 2534 2583 29.16 29.5 32.33 31.03 30.2 29.85 30.33 30.36 3033 2870 2799 2532 2900.666667 0.014748322 0.182356723 GO:0000346///transcription export complex GO:0003729///mRNA binding+++GO:0046872///metal ion binding GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 70584 70584 'Pak4' mRNA 1734 1781 1620 32.78 33.27 32.64 23.43 22.53 22.41 32.89666667 22.79 1420 1336 1317 1711.666667 1357.666667 3.54E-06 -0.345348628 04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04360///Axon guidance+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05170///Human immunodeficiency virus 1 infection+++05206///MicroRNAs in cancer+++05211///Renal cell carcinoma GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0045766///positive regulation of angiogenesis+++GO:0060996///dendritic spine development+++GO:0071407///cellular response to organic cyclic compound+++GO:2000352///negative regulation of endothelial cell apoptotic process 70591 70591 '5730455P16Rik' mRNA 1065 1171 1051 13.81 14.85 14.38 9.87 9.99 9.17 14.34666667 9.676666667 879 862 804 1095.666667 848.3333333 3.61E-05 -0.38013355 GO:0005802///trans-Golgi network+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0099041///vesicle tethering to Golgi 70598 70598 'Filip1' mRNA 851 892 744 8.47 8.88 7.95 4.35 4.79 4.35 8.433333333 4.496666667 479 510 465 829 484.6666667 1.43E-13 -0.782776062 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse GO:0003674///molecular_function GO:0099010///modification of postsynaptic structure 70599 70599 'Itprid2' mRNA 779 753 541 10.2 9.57 7.62 8.86 8.41 8.69 9.13 8.653333333 735 714 723 691 724 0.702250068 0.062072653 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0051015///actin filament binding 70601 70601 'Ecd' mRNA 1358 1489 1295 23.8 25.68 24.08 19.76 19.56 18.26 24.52 19.19333333 1297 1254 1161 1380.666667 1237.333333 0.059871567 -0.16858826 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0035035///histone acetyltransferase binding GO:0006397///mRNA processing+++GO:0008283///cell proliferation+++GO:0008380///RNA splicing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 70603 70603 'Mutyh' mRNA 156.51 176.42 195.01 5.24 5.82 6.9 3.53 3.43 3.73 5.986666667 3.563333333 121.78 112.54 121.17 175.98 118.4966667 0.007616693 -0.590145259 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0000701///purine-specific mismatch base pair DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019104///DNA N-glycosylase activity+++GO:0032357///oxidized purine DNA binding+++GO:0032407///MutSalpha complex binding+++GO:0034039///8-oxo-7,8-dihydroguanine DNA N-glycosylase activity+++GO:0035485///adenine/guanine mispair binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006298///mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0060546///negative regulation of necroptotic process 70604 70604 'Dnajb14' mRNA 826.43 775.59 640.89 13.05 12.38 10.13 11.25 12.15 11.25 11.85333333 11.55 769.97 763.21 781.79 747.6366667 771.6566667 0.796280494 0.037833883 GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0030544///Hsp70 protein binding GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0034622///cellular protein-containing complex assembly+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071218///cellular response to misfolded protein 70605 70605 'Zdhhc24' mRNA 816 780 834 18.02 16.79 19.77 14.43 14.41 14.27 18.19333333 14.37 752 738 720 810 736.6666667 0.189949658 -0.150606818 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation 70611 70611 'Fbxo33' mRNA 310.23 273.47 298.35 4.5 3.9 4.54 4.41 3.79 4.74 4.313333333 4.313333333 352.23 285.77 358.69 294.0166667 332.23 0.380056548 0.16103026 GO:0005575///cellular_component+++GO:0019005///SCF ubiquitin ligase complex GO:0003674///molecular_function GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination 70612 70612 'Tmem230' mRNA 936 1011 944 34.47 36.71 36.85 34.24 33.46 33.83 36.01 33.84333333 1068 1018 1019 963.6666667 1035 0.383485048 0.09116889 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0048489///synaptic vesicle transport 70615 70615 'Ankrd24' mRNA 2128 2186 1355 25.59 26.23 16.55 3.88 4.7 4.41 22.79 4.33 371 421 411 1889.666667 401 2.69E-65 -2.2368217 GO:0005575///cellular_component GO:0005515///protein binding GO:0008150///biological_process 70616 70616 'Sugp1' mRNA 1091 1134 1035 26.3 26.72 25.68 21.57 24.23 25.47 26.23333333 23.75666667 1084 1160 1170 1086.666667 1138 0.616106802 0.056611199 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 70617 70617 'Fam241a' mRNA 98 125 64 3.58 4.5 2.48 2.45 2.7 2.1 3.52 2.416666667 77 83 64 95.66666667 74.66666667 0.296136239 -0.357835447 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 70620 70620 'Ube2v2' mRNA 1215.42 1230.41 1239.66 14.14 14.31 15.36 14.12 14.53 13.78 14.60333333 14.14333333 1385.89 1391.91 1297.06 1228.496667 1358.286667 0.162486775 0.132090639 04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031372///UBC13-MMS2 complex GO:0005515///protein binding GO:0000209///protein polyubiquitination+++GO:0000729///DNA double-strand break processing+++GO:0006301///postreplication repair+++GO:0010976///positive regulation of neuron projection development+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0042275///error-free postreplication DNA repair+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045739///positive regulation of DNA repair+++GO:0051965///positive regulation of synapse assembly+++GO:0070534///protein K63-linked ubiquitination 70625 70625 'Med26' mRNA 435 412 430 7.85 7.32 8.23 5.77 6.52 6.35 7.8 6.213333333 368 406 392 425.6666667 388.6666667 0.356907815 -0.143171174 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression 70638 70638 'Fam189a1' mRNA 5 2 3 0.06 0.02 0.04 0.03 0.07 0.03 0.04 0.043333333 3 7 3 3.333333333 4.333333333 0.83298145 0.373220634 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 70640 70640 'Dcp2' mRNA 221.04 250 193 1.34 1.49 1.24 1.58 1.68 1.65 1.356666667 1.636666667 299 310.83 303 221.3466667 304.2766667 0.005870756 0.450154021 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016442///RISC complex+++GO:0030054///cell junction+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003723///RNA binding+++GO:0004534///5'-3' exoribonuclease activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0006402///mRNA catabolic process+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0043488///regulation of mRNA stability+++GO:0071044///histone mRNA catabolic process+++GO:1904872///regulation of telomerase RNA localization to Cajal body" 70645 70645 'Oip5' mRNA 28 23 29 1.06 0.86 1.16 2.4 3.08 2.75 1.026666667 2.743333333 73 91.61 80.87 26.66666667 81.82666667 5.58E-06 1.596257184 "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0010369///chromocenter+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle" GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051301///cell division 70646 70646 'Naa30' mRNA 215 219 184 2.61 2.61 2.37 2.63 2.06 2.6 2.53 2.43 250 191 239 206 226.6666667 0.569326204 0.127163096 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0031417///NatC complex "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0017196///N-terminal peptidyl-methionine acetylation 70650 70650 'Zcchc8' mRNA 758 650 650 15.58 12.76 14.38 12.47 12.33 13.39 14.24 12.73 716 702 727 686 715 0.741194687 0.048578343 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016604///nuclear body+++GO:0031499///TRAMP complex+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0034470///ncRNA processing 70652 70652 'Tmem144' mRNA 74 81 68 1.46 1.59 1.44 2.17 2.92 2.15 1.496666667 2.413333333 125 163 121 74.33333333 136.3333333 7.75E-04 0.867627052 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0015144///carbohydrate transmembrane transporter activity GO:0008150///biological_process+++GO:0034219///carbohydrate transmembrane transport 70661 70661 'Sik3' mRNA 577 543 427 4.86 4.5 3.82 3.81 3.89 3.54 4.393333333 3.746666667 521 519 467 515.6666667 502.3333333 0.802058089 -0.044834937 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0050321///tau-protein kinase activity GO:0000226///microtubule cytoskeleton organization+++GO:0001958///endochondral ossification+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0032880///regulation of protein localization+++GO:0035108///limb morphogenesis+++GO:0035264///multicellular organism growth+++GO:0035556///intracellular signal transduction+++GO:0048705///skeletal system morphogenesis+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:1904263///positive regulation of TORC1 signaling+++GO:1904515///positive regulation of TORC2 signaling 70673 70673 'Prdm16' mRNA 482 509 407 2.92 3.02 2.63 2.08 2.06 2.49 2.856666667 2.21 402 380 455 466 412.3333333 0.213153356 -0.184620693 00310///Lysine degradation+++04714///Thermogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0017053///transcriptional repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0033613///activating transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0032259///methylation+++GO:0035019///somatic stem cell population maintenance+++GO:0043457///regulation of cellular respiration+++GO:0043586///tongue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048468///cell development+++GO:0050872///white fat cell differentiation+++GO:0050873///brown fat cell differentiation+++GO:0051567///histone H3-K9 methylation+++GO:0060021///roof of mouth development+++GO:0070828///heterochromatin organization+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis" 70675 70675 'Vcpip1' mRNA 831 834 750 4.46 4.4 4.27 5.42 4.94 5.11 4.376666667 5.156666667 1162 1034 1062 805 1086 3.05E-06 0.420837299 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0045202///synapse GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0000278///mitotic cell cycle+++GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007030///Golgi organization+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0016567///protein ubiquitination+++GO:0016579///protein deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0090168///Golgi reassembly+++GO:1905634///regulation of protein localization to chromatin 70676 70676 'Gulp1' mRNA 827 826 827 15.02 14.7 15.95 9.15 8.24 9.88 15.22333333 9.09 576 510 603 826.6666667 563 1.23E-07 -0.567310282 GO:0005737///cytoplasm GO:0003674///molecular_function "GO:0006869///lipid transport+++GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0006915///apoptotic process" 70681 70681 'Abraxas1' mRNA 214 234 197 5.52 5.42 5.14 4.04 5.3 4.56 5.36 4.633333333 200 252 201 215 217.6666667 0.970880597 0.010138483 03440///Homologous recombination GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0070531///BRCA1-A complex GO:0008017///microtubule binding+++GO:0031593///polyubiquitin modification-dependent protein binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0010212///response to ionizing radiation+++GO:0045739///positive regulation of DNA repair+++GO:0070536///protein K63-linked deubiquitination+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0090307///mitotic spindle assembly 70683 70683 'Utp20' mRNA 145 161 147 0.86 0.94 0.93 1.35 1.15 1.33 0.91 1.276666667 262 218 249 151 243 2.18E-04 0.673959507 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0030686///90S preribosome+++GO:0032040///small-subunit processome GO:0006364///rRNA processing 70686 70686 'Dusp16' mRNA 910 976 872 9.47 10.04 9.62 7.3 6.45 6.51 9.71 6.753333333 783 685 670 919.3333333 712.6666667 1.48E-04 -0.379066684 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008330///protein tyrosine/threonine phosphatase activity+++GO:0016301///kinase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0051019///mitogen-activated protein kinase binding GO:0000188///inactivation of MAPK activity+++GO:0006470///protein dephosphorylation+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043409///negative regulation of MAPK cascade 70691 70691 '3830403N18Rik' mRNA 23.38 8.02 9.58 1.46 0.49 0.63 2.55 2.04 2.31 0.86 2.3 46.93 36.62 40.96 13.66 41.50333333 0.003288445 1.600552608 GO:0000795///synaptonemal complex+++GO:0000800///lateral element+++GO:0005634///nucleus GO:0003674///molecular_function "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007286///spermatid development+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0051321///meiotic cell cycle" 70693 70693 'Adgra3' mRNA 480 522 451 5.76 6.16 5.74 3.21 3.3 3.55 5.886666667 3.353333333 308 309 330 484.3333333 315.6666667 1.12E-06 -0.6272908 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway 70696 70696 'Magea9' mRNA 2 1 6 0.07 0.04 0.23 0 0.13 0 0.113333333 0.043333333 0 4 0 3 1.333333333 0.615748503 -1.198635258 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 70699 70699 'Nup205' mRNA 365 359 355 3.72 3.5 3.69 4.64 4.25 4.03 3.636666667 4.306666667 532 478 460 359.6666667 490 8.19E-04 0.433207218 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery+++GO:0044611///nuclear pore inner ring GO:0017056///structural constituent of nuclear pore GO:0006913///nucleocytoplasmic transport+++GO:0006999///nuclear pore organization+++GO:0051292///nuclear pore complex assembly 70701 70701 'Nipal1' mRNA 614 612 639 7.86 7.71 8.68 7.96 7.24 7.63 8.083333333 7.61 716 636 664 621.6666667 672 0.458221257 0.098096257 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0015095///magnesium ion transmembrane transporter activity GO:0006811///ion transport+++GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 70713 70713 'Gpr137c' mRNA 121 101 101 1.94 1.57 1.68 1.49 0.86 1.04 1.73 1.13 113 63 70 107.6666667 82 0.196209483 -0.408964369 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:1904263///positive regulation of TORC1 signaling 70717 70717 'Medag' mRNA 135.04 156.63 132 2.51 2.88 2.63 12.76 11.39 12.14 2.673333333 12.09666667 788.49 686 725 141.2233333 733.1633333 3.68E-71 2.366882178 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0045600///positive regulation of fat cell differentiation 70719 70719 'Arhgap45' mRNA 138 99 115 1.9 1.34 1.73 15.96 14.73 15.25 1.656666667 15.31333333 1333 1201 1230 117.3333333 1254.666667 1.27E-156 3.405956328 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 70726 70726 'Angptl6' mRNA 154.31 126.89 151.7 5.61 4.45 5.89 3.43 3.41 3.22 5.316666667 3.353333333 106.3 102.97 100.17 144.3 103.1466667 0.038628159 -0.499611538 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030141///secretory granule+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation 70727 70727 'Rasgef1a' mRNA 202 227 175 3.41 3.77 3.13 2.1 1.77 2.04 3.436666667 1.97 143 118 135 201.3333333 132 0.002127222 -0.61811046 GO:0005575///cellular_component GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity 70729 70729 'Nos1ap' mRNA 1627 1803 1544 17.38 18.94 17.49 2.62 2.94 3.6 17.93666667 3.053333333 282 310 376 1658 322.6666667 6.44E-105 -2.370000554 04713///Circadian entrainment GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005901///caveola+++GO:0030018///Z disc+++GO:0030315///T-tubule+++GO:0031965///nuclear membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0002020///protease binding+++GO:0030165///PDZ domain binding+++GO:0050998///nitric-oxide synthase binding GO:0003062///regulation of heart rate by chemical signal+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1901215///negative regulation of neuron death+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:2000170///positive regulation of peptidyl-cysteine S-nitrosylation 70730 70730 '6330409D20Rik' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70737 70737 'Cgn' mRNA 5287 5203 5347 56.77 54.87 61.29 17.96 16.71 17.28 57.64333333 17.31666667 1915 1747 1786 5279 1816 9.48E-123 -1.553498534 04530///Tight junction GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0005923///bicellular tight junction+++GO:0016459///myosin complex+++GO:0030054///cell junction+++GO:0043296///apical junction complex GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0003382///epithelial cell morphogenesis+++GO:0070830///bicellular tight junction assembly 70747 70747 'Tspan2' mRNA 724 819 712 9.39 10.26 9.75 2.12 1.52 1.92 9.8 1.853333333 189 135 164 751.6666667 162.6666667 8.32E-60 -2.220491731 GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath GO:0003674///molecular_function GO:0006954///inflammatory response+++GO:0007420///brain development+++GO:0014002///astrocyte development+++GO:0014005///microglia development+++GO:0042552///myelination+++GO:0048709///oligodendrocyte differentiation+++GO:0061564///axon development 70750 70750 'Kdsr' mRNA 959.21 1076.28 1074.11 16.26 17.87 18.48 18.36 14.83 16.79 17.53666667 16.66 1243.52 1097.45 1203.46 1036.533333 1181.476667 0.096694567 0.174204931 00600///Sphingolipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity+++GO:0047560///3-dehydrosphinganine reductase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006666///3-keto-sphinganine metabolic process+++GO:0030148///sphingolipid biosynthetic process 70757 70757 'Hacd2' mRNA 1127.81 1192.96 998 13.81 14.66 13.83 13.57 16.26 16.65 14.1 15.49333333 1245 1362 1382.01 1106.256667 1329.67 0.00577729 0.258181754 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0016829///lyase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0019899///enzyme binding+++GO:0080023///3R-hydroxyacyl-CoA dehydratase activity+++GO:0102158///very-long-chain 3-hydroxyacyl-CoA dehydratase activity+++GO:0102343///3-hydroxy-arachidoyl-CoA dehydratase activity+++GO:0102344///3-hydroxy-behenoyl-CoA dehydratase activity+++GO:0102345///3-hydroxy-lignoceroyl-CoA dehydratase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0042761///very long-chain fatty acid biosynthetic process 70762 70762 'Dclk2' mRNA 675 619 641 7.59 7.03 7.79 5.94 6.58 5.44 7.47 5.986666667 573 621 524 645 572.6666667 0.158743682 -0.183584484 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0021766///hippocampus development+++GO:0021860///pyramidal neuron development+++GO:0035556///intracellular signal transduction+++GO:1900181///negative regulation of protein localization to nucleus 70767 70767 'Prpf3' mRNA 617 553 600 12.76 11.11 13 10.74 11.47 12.29 12.29 11.5 601 632 666 590 633 0.54112821 0.088864666 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome GO:0042802///identical protein binding "GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 70769 70769 'Nolc1' mRNA 803 880 825 11.9 12.83 12.96 12.11 12.2 10.77 12.56333333 11.69333333 941 926 810 836 892.3333333 0.511411657 0.082016919 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0031428///box C/D snoRNP complex+++GO:0031429///box H/ACA snoRNP complex "GO:0001093///TFIIB-class transcription factor binding+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0019904///protein domain specific binding+++GO:0030674///protein binding, bridging+++GO:0034512///box C/D snoRNA binding+++GO:0034513///box H/ACA snoRNA binding+++GO:0046982///protein heterodimerization activity+++GO:0062064///box C/D snoRNP complex binding+++GO:0062065///box H/ACA snoRNP complex binding" "GO:0006417///regulation of translation+++GO:0006970///response to osmotic stress+++GO:0007000///nucleolus organization+++GO:0008284///positive regulation of cell proliferation+++GO:0014029///neural crest formation+++GO:0014032///neural crest cell development+++GO:0033979///box H/ACA snoRNA metabolic process+++GO:0042306///regulation of protein import into nucleus+++GO:0045893///positive regulation of transcription, DNA-templated" 70771 70771 'Gpr173' mRNA 42 66 46 0.46 0.71 0.53 0.69 0.68 0.51 0.566666667 0.626666667 72 69 52 51.33333333 64.33333333 0.434504924 0.31695926 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004968///gonadotropin-releasing hormone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097211///cellular response to gonadotropin-releasing hormone+++GO:2001223///negative regulation of neuron migration 70772 70772 'Ggnbp1' mRNA 104 104 80 5.21 5.14 4.3 3.44 2.64 2.56 4.883333333 2.88 73 56 54 96 61 0.026204177 -0.663492962 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding GO:0000266///mitochondrial fission+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 70779 70779 'Prdm5' mRNA 172 182 177 4.35 4.45 4.73 4.09 3.59 4.53 4.51 4.07 184 164 198 177 182 0.911197198 0.027528267 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation+++GO:0032259///methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051567///histone H3-K9 methylation+++GO:1990830///cellular response to leukemia inhibitory factor" 70784 70784 'Rasl12' mRNA 265 327 323 5.98 7.29 7.65 3.45 3.17 3.65 6.973333333 3.423333333 176 157 179 305 170.6666667 1.13E-06 -0.85210836 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0007165///signal transduction 70785 70785 'Dennd1c' mRNA 66 59 54 1.52 1.34 1.33 5.27 4.88 4.54 1.396666667 4.896666667 268 243 223 59.66666667 244.6666667 1.07E-21 2.02484849 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:1901981///phosphatidylinositol phosphate binding GO:0006897///endocytosis+++GO:0032456///endocytic recycling+++GO:0050790///regulation of catalytic activity 70788 70788 'Klhl30' mRNA 54 76 57 0.98 1.36 1.1 0.28 0.58 0.29 1.146666667 0.383333333 18 36 18 62.33333333 24 0.001203811 -1.380910337 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70789 70789 'Kynu' mRNA 1 0 0 0.04 0 0 0.22 0.17 0.2 0.013333333 0.196666667 9 6 7 0.333333333 7.333333333 0.013934263 4.340049282 00380///Tryptophan metabolism+++01240///Biosynthesis of cofactors GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0030429///kynureninase activity+++GO:0042803///protein homodimerization activity+++GO:0061981///3-hydroxykynureninase activity GO:0006569///tryptophan catabolic process+++GO:0007568///aging+++GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0019441///tryptophan catabolic process to kynurenine+++GO:0019442///tryptophan catabolic process to acetyl-CoA+++GO:0019805///quinolinate biosynthetic process+++GO:0034341///response to interferon-gamma+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0034516///response to vitamin B6+++GO:0043420///anthranilate metabolic process+++GO:0097053///L-kynurenine catabolic process 70790 70790 'Ubr5' mRNA 1104.08 1102.62 1139.79 5.58 5.41 6.27 7.04 6.38 7.32 5.753333333 6.913333333 1542.72 1344.92 1517.42 1115.496667 1468.353333 2.02E-05 0.3823083 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010628///positive regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032700///negative regulation of interleukin-17 production+++GO:0042307///positive regulation of protein import into nucleus+++GO:0050847///progesterone receptor signaling pathway+++GO:0070936///protein K48-linked ubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1901315///negative regulation of histone H2A K63-linked ubiquitination+++GO:2000779///regulation of double-strand break repair+++GO:2000780///negative regulation of double-strand break repair 70791 70791 'Hars2' mRNA 776 743 711 14.69 14.51 14.44 11.75 11.38 10.49 14.54666667 11.20666667 666 641 580 743.3333333 629 0.022218875 -0.252527472 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004821///histidine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042802///identical protein binding GO:0006412///translation+++GO:0006427///histidyl-tRNA aminoacylation 70796 70796 'Zdhhc1' mRNA 1613 1494 1412 42.28 38.69 39.47 19.69 19.12 21.66 40.14666667 20.15666667 867 813 919 1506.333333 866.3333333 5.95E-21 -0.808863043 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0002230///positive regulation of defense response to virus by host+++GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation+++GO:0032461///positive regulation of protein oligomerization+++GO:1905668///positive regulation of protein localization to endosome 70797 70797 'Ankib1' mRNA 410 448 267 3.3 3.52 2.34 2.56 2.92 3.46 3.053333333 2.98 356 396 472 375 408 0.58521442 0.121198129 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process 70799 70799 'Cep192' mRNA 169 152 152 1.1 0.97 1.05 1.84 1.61 1.85 1.04 1.766666667 327 280 319 157.6666667 308.6666667 8.81E-09 0.956719229 GO:0000242///pericentriolar material+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding GO:0007020///microtubule nucleation+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007099///centriole replication+++GO:0009617///response to bacterium+++GO:0010923///negative regulation of phosphatase activity+++GO:0046599///regulation of centriole replication+++GO:0046605///regulation of centrosome cycle+++GO:0051298///centrosome duplication+++GO:0070201///regulation of establishment of protein localization+++GO:0071539///protein localization to centrosome+++GO:0090222///centrosome-templated microtubule nucleation+++GO:0090307///mitotic spindle assembly 70802 70802 'Pwwp2a' mRNA 640.81 531.66 528.45 7.71 6.24 6.77 5.33 5.27 5.23 6.906666667 5.276666667 511.91 488.81 468.15 566.9733333 489.6233333 0.092575729 -0.222985196 GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0008150///biological_process 70804 70804 'Pgrmc2' mRNA 424 444 307 7.74 7.98 5.95 5.19 4.19 4.52 7.223333333 4.633333333 327 258 276 391.6666667 287 0.005487275 -0.455459021 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015232///heme transporter activity+++GO:0020037///heme binding GO:0015886///heme transport+++GO:0060612///adipose tissue development 70807 70807 'Arrdc2' mRNA 1133 1153 1088 26.85 26.92 27.36 20.96 20.33 22.25 27.04333333 21.18 1019 961 1047 1124.666667 1009 0.07020994 -0.168131602 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0015031///protein transport 70810 70810 'Krt25' mRNA 2 2 1 0.06 0.06 0.03 0 0.03 0 0.05 0.01 0 1 0 1.666666667 0.333333333 0.467285742 -2.216848289 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005882///intermediate filament GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity GO:0007010///cytoskeleton organization+++GO:0007568///aging+++GO:0031069///hair follicle morphogenesis+++GO:0042633///hair cycle+++GO:0045109///intermediate filament organization 70821 70821 '4921507P07Rik' mRNA 44 46 33 0.97 0.87 0.73 0.23 0.35 0.49 0.856666667 0.356666667 13 18 24 41 18.33333333 0.01729302 -1.16436042 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 70823 70823 'Hmgxb4' mRNA 385 409 381 5.26 5.57 5.56 5.29 4.32 5.19 5.463333333 4.933333333 447 355 425 391.6666667 409 0.791419236 0.049538884 GO:0005634///nucleus+++GO:0016589///NURF complex GO:0003677///DNA binding+++GO:0042802///identical protein binding 70827 70827 'Trak2' mRNA 1408 1534 1356 11.96 12.83 12.22 11.23 11.08 10.81 12.33666667 11.04 1519 1466 1419 1432.666667 1468 0.826934315 0.024451684 04727///GABAergic synapse GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0032839///dendrite cytoplasm+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:1904115///axon cytoplasm GO:0005102///signaling receptor binding+++GO:0017022///myosin binding+++GO:0019894///kinesin binding+++GO:0019899///enzyme binding+++GO:0030911///TPR domain binding+++GO:0050811///GABA receptor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006493///protein O-linked glycosylation+++GO:0006605///protein targeting+++GO:0008333///endosome to lysosome transport+++GO:0022008///neurogenesis+++GO:0047496///vesicle transport along microtubule+++GO:0048311///mitochondrion distribution+++GO:0048813///dendrite morphogenesis+++GO:0050771///negative regulation of axonogenesis+++GO:0098939///dendritic transport of mitochondrion+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0098972///anterograde dendritic transport of mitochondrion 70829 70829 'Ccdc93' mRNA 618 656 576 4.49 4.69 4.44 3.65 3.64 3.43 4.54 3.573333333 578 563 527 616.6666667 556 0.188989508 -0.159765885 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling 70834 70834 'Spag9' mRNA 2110 2196 2072 15.36 15.63 16.01 10.08 10.3 10.23 15.66666667 10.20333333 1609 1605 1578 2126 1597.333333 1.87E-09 -0.423951907 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0048471///perinuclear region of cytoplasm GO:0005078///MAP-kinase scaffold activity+++GO:0005515///protein binding+++GO:0008432///JUN kinase binding+++GO:0019894///kinesin binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0042802///identical protein binding+++GO:0048273///mitogen-activated protein kinase p38 binding "GO:0000187///activation of MAPK activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0007254///JNK cascade+++GO:0007257///activation of JUN kinase activity+++GO:0016192///vesicle-mediated transport+++GO:0030335///positive regulation of cell migration+++GO:0032418///lysosome localization+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043410///positive regulation of MAPK cascade+++GO:0045665///negative regulation of neuron differentiation+++GO:0045666///positive regulation of neuron differentiation+++GO:0051146///striated muscle cell differentiation+++GO:1903860///negative regulation of dendrite extension" 70835 70835 'Prss22' mRNA 13 10 14 0.59 0.41 0.68 9.2 8.2 9.59 0.56 8.996666667 236 208 238 12.33333333 227.3333333 2.77E-40 4.190658235 GO:0005615///extracellular space GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016504///peptidase activator activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0010952///positive regulation of peptidase activity 70839 70839 'P2ry12' mRNA 59 51 63 1.33 1.13 1.47 6.43 7.12 6.87 1.31 6.806666667 326 353 337 57.66666667 338.6666667 5.51E-38 2.541051216 04611///Platelet activation GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005901///caveola+++GO:0009897///external side of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0031253///cell projection membrane+++GO:0044298///cell body membrane GO:0001609///G protein-coupled adenosine receptor activity+++GO:0001621///ADP receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity "GO:0001973///adenosine receptor signaling pathway+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008347///glial cell migration+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0019722///calcium-mediated signaling+++GO:0021808///cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration+++GO:0030030///cell projection organization+++GO:0030032///lamellipodium assembly+++GO:0030168///platelet activation+++GO:0033626///positive regulation of integrin activation by cell surface receptor linked signal transduction+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0035585///calcium-mediated signaling using extracellular calcium source+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0043270///positive regulation of ion transport+++GO:0043491///protein kinase B signaling+++GO:0045596///negative regulation of cell differentiation+++GO:0048678///response to axon injury+++GO:0050920///regulation of chemotaxis+++GO:0050921///positive regulation of chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051924///regulation of calcium ion transport+++GO:0070527///platelet aggregation+++GO:0070588///calcium ion transmembrane transport+++GO:0071318///cellular response to ATP+++GO:0071407///cellular response to organic cyclic compound+++GO:0071805///potassium ion transmembrane transport+++GO:0150063///visual system development+++GO:1900029///positive regulation of ruffle assembly+++GO:1904139///regulation of microglial cell migration+++GO:1904141///positive regulation of microglial cell migration" 70843 70843 'Krt28' mRNA 4 4 10 0.16 0.13 0.36 0 0.04 0.04 0.216666667 0.026666667 0 1 1 6 0.666666667 0.066422313 -3.198891545 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005737///cytoplasm+++GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 70846 70846 'Ttc6' mRNA 11 11 5 0.21 0.22 0.06 0.2 0.03 0.2 0.163333333 0.143333333 15 2 14 9 10.33333333 0.863357859 0.191952827 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0016740///transferase activity GO:0008150///biological_process+++GO:0009740///gibberellic acid mediated signaling pathway 70853 70853 'Vwa3b' mRNA 402 476 357 5.62 6.51 4.94 0.8 0.49 0.48 5.69 0.59 64 34 43 411.6666667 47 5.73E-50 -3.141283212 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 70859 70859 'Lrrc63' mRNA 7 5 6 0.2 0.14 0.18 0.17 0.1 0.1 0.173333333 0.123333333 7 4 4 6 5 0.851450316 -0.281004498 GO:0005575///cellular_component GO:0003674///molecular_function 70861 70861 'Akr1cl' mRNA 64 70 91 2.8 3.12 4.27 0.99 0.95 0.67 3.396666667 0.87 26 24 17 75 22.33333333 4.50E-06 -1.768316319 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0001758///retinal dehydrogenase activity+++GO:0003674///molecular_function+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004745///retinol dehydrogenase activity+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0018636///phenanthrene 9,10-monooxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0032052///bile acid binding+++GO:0035410///dihydrotestosterone 17-beta-dehydrogenase activity+++GO:0045550///geranylgeranyl reductase activity+++GO:0045703///ketoreductase activity+++GO:0047020///15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity+++GO:0047023///androsterone dehydrogenase activity+++GO:0047042///androsterone dehydrogenase (B-specific) activity+++GO:0047086///ketosteroid monooxygenase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047743///chlordecone reductase activity+++GO:0047787///delta4-3-oxosteroid 5beta-reductase activity+++GO:0047834///D-threo-aldose 1-dehydrogenase activity" GO:0006693///prostaglandin metabolic process+++GO:0008150///biological_process+++GO:0008202///steroid metabolic process+++GO:0042448///progesterone metabolic process+++GO:0044597///daunorubicin metabolic process+++GO:0044598///doxorubicin metabolic process 70873 70873 'Cnbd2' mRNA 430.05 426.8 347.48 9.87 9.74 8.34 16.4 19.78 17.25 9.316666667 17.81 743.73 892.99 781.61 401.4433333 806.11 1.84E-16 0.999522565 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0030552///cAMP binding GO:0007283///spermatogenesis 70881 70881 'Nt5c1b' mRNA 0 1 0 0 0.03 0 0.11 0.08 0.04 0.01 0.076666667 4 2 1 0.333333333 2.333333333 0.315492785 2.682485046 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity GO:0000255///allantoin metabolic process+++GO:0006196///AMP catabolic process+++GO:0009116///nucleoside metabolic process+++GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation+++GO:0046085///adenosine metabolic process 70882 70882 'Armc3' mRNA 207 293 250 3.91 5.4 4.92 0.69 1.03 1.19 4.743333333 0.97 42 62 69 250 57.66666667 8.35E-19 -2.124910752 GO:0003674///molecular_function GO:0008150///biological_process 70884 70884 'Ccdc81' mRNA 1293 1412 1370 26.61 28.6 29.91 1.56 1.34 1.87 28.37333333 1.59 87 73 101 1358.333333 87 4.36E-192 -3.97783789 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0008150///biological_process 70885 70885 'Ints10' mRNA 991 969 1041 14.12 13.93 16.54 10.85 10.73 9.3 14.86333333 10.29333333 828 788 698 1000.333333 771.3333333 2.69E-04 -0.389721962 GO:0005634///nucleus+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing 70887 70887 'Dmrtc1a' mRNA 104 80 87 5.46 3.94 5.08 1.66 2.18 1.1 4.826666667 1.646666667 37 46 25 90.33333333 36 8.66E-05 -1.338322854 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 70891 70891 'Spdya' mRNA 127 108 100 4.97 3.8 3.98 4.31 2.92 4.22 4.25 3.816666667 110 81 119 111.6666667 103.3333333 0.718125894 -0.123079103 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007140///male meiotic nuclear division+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0032147///activation of protein kinase activity+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045860///positive regulation of protein kinase activity 70892 70892 'Ttll7' mRNA 497 489 422 4.51 3.99 4.65 0.63 1.17 1.25 4.383333333 1.016666667 99 108 125 469.3333333 110.6666667 2.08E-39 -2.09269718 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0030425///dendrite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0097731///9+0 non-motile cilium GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0018095///protein polyglutamylation+++GO:0030154///cell differentiation 70894 70894 'Efcab3' mRNA 2 3 2 0.04 0.04 0.03 0.01 0.03 0 0.036666667 0.013333333 1 2 0 2.333333333 1 0.613811745 -1.22495095 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 70896 70896 'Speer1' mRNA 0 0 1.17 0 0 0.07 0 0 0.12 0.023333333 0.04 0 0 2.46 0.39 0.82 0.863090843 0.890621057 70897 70897 'Fam71d' mRNA 3 2 1 0.09 0.07 0.04 0 0 0 0.066666667 0 0 0 0 2 0 0.251097854 -3.439033012 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 70900 70900 '4921517D22Rik' mRNA 3 0 1.02 0.05 0 0.02 0 0.03 0.02 0.023333333 0.016666667 0 1.79 1 1.34 0.93 0.77183396 -0.999183411 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70902 70902 'Lpcat2b' mRNA 1 4 6 0.02 0.08 0.13 0 0 0.02 0.076666667 0.006666667 0 0 1 3.666666667 0.333333333 0.130425173 -3.387499857 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008150///biological_process+++GO:0008654///phospholipid biosynthetic process 70909 70909 '4921504E06Rik' mRNA 0 2 0 0 0.06 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70911 70911 'Phyhipl' mRNA 272.87 296.5 307.35 5.23 5.6 6.25 2.14 1.72 1.57 5.693333333 1.81 128.2 100.48 91.24 292.24 106.64 1.54E-14 -1.471923405 GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 70918 70918 'Nsun7' mRNA 41.35 37.66 24.37 0.33 0.29 0.22 0.22 0.25 0.28 0.28 0.25 29.3 35.79 41.27 34.46 35.45333333 0.945253894 0.040128868 GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0030317///flagellated sperm motility+++GO:0030382///sperm mitochondrion organization+++GO:0032259///methylation 70920 70920 'Tex47' mRNA 5 8.37 9.02 0.06 0.12 0.04 0.02 0.02 0.02 0.073333333 0.02 4.98 7.01 6.48 7.463333333 6.156666667 0.761096634 -0.386105329 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70925 70925 'Cdkn2aip' mRNA 807 775 826 12.62 11.93 13.71 9.68 8.27 8.85 12.75333333 8.933333333 713 595 632 802.6666667 646.6666667 0.003765523 -0.32686131 GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0002039///p53 binding+++GO:0003723///RNA binding GO:0006974///cellular response to DNA damage stimulus+++GO:0009967///positive regulation of signal transduction+++GO:0030307///positive regulation of cell growth+++GO:0030308///negative regulation of cell growth+++GO:0031647///regulation of protein stability 70928 70928 'Trim69' mRNA 0 1 0 0 0.04 0 0.03 0.07 0.13 0.013333333 0.076666667 1 2 4 0.333333333 2.333333333 0.311016458 2.69762148 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination 70930 70930 'Nol8' mRNA 245 282 275 2.83 3.2 3.38 3.58 3.45 3.33 3.136666667 3.453333333 357 336 322 267.3333333 338.3333333 0.040257813 0.326460216 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0006364///rRNA processing+++GO:1902570///protein localization to nucleolus+++GO:1990830///cellular response to leukemia inhibitory factor 70941 70941 '4921539E11Rik' mRNA 1 1 0 0.04 0.04 0 0 0 0 0.026666667 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70945 70945 'Mmrn1' mRNA 2 0 2 0.02 0 0.02 0 0.07 0.05 0.013333333 0.04 0 7 5 1.333333333 4 0.448040775 1.572106944 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding GO:0007596///blood coagulation 70951 70951 'Spata1' mRNA 34.12 34 32.5 1.04 1.04 1.09 0.44 0.82 0.41 1.056666667 0.556666667 16.1 27.22 13.02 33.54 18.78 0.120924642 -0.844187316 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70952 70952 'Poteg' mRNA 2 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70967 70967 'Eva1c' mRNA 629 648 682 19.39 19.79 21.68 22.46 21.4 20.55 20.28666667 21.47 791 784 706 653 760.3333333 0.084872039 0.205548331 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008201///heparin binding+++GO:0030246///carbohydrate binding GO:0008150///biological_process 70974 70974 'Pgm2l1' mRNA 3210 3379 3199 19.56 20.22 20.67 3.11 2.49 3.29 20.15 2.963333333 588 459 602 3262.666667 549.6666667 4.61E-185 -2.582630646 00500///Starch and sucrose metabolism "GO:0016740///transferase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0046872///metal ion binding+++GO:0047933///glucose-1,6-bisphosphate synthase activity" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0016310///phosphorylation+++GO:0071704///organic substance metabolic process 70976 70976 'Ccdc105' mRNA 7 1 3 0.29 0.03 0.13 0 0 0.15 0.15 0.05 0 0 3 3.666666667 1 0.387177547 -1.880982838 GO:0003674///molecular_function GO:0008150///biological_process 70979 70979 'Fancd2os' mRNA 0 1.07 2.08 0 0.05 0.09 0 0.04 0.04 0.046666667 0.026666667 0 1 1.2 1.05 0.733333333 0.863090843 -0.613866572 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70981 70981 'Potegl' mRNA 11 12 18 0.12 0.11 0.2 0.03 0.02 0.03 0.143333333 0.026666667 4 3 4 13.66666667 3.666666667 0.037099145 -1.922199571 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70984 70984 '4931406C07Rik' mRNA 323 329 334 6.73 6.76 7.36 9.93 9.8 9.97 6.95 9.9 548 530 532 328.6666667 536.6666667 2.09E-08 0.694557898 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body "GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding" 70986 70986 '4931422A03Rik' mRNA 17.02 37.07 28.05 0.98 2.11 1.71 1.36 1.08 1.3 1.6 1.246666667 27.05 21.04 25.02 27.38 24.37 0.794840531 -0.180527201 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 70989 70989 'Jhy' mRNA 30 20 33 0.55 0.36 0.62 0.09 0.36 0.19 0.51 0.213333333 5 20 12 27.66666667 12.33333333 0.075940659 -1.177096601 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0007420///brain development+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0035082///axoneme assembly+++GO:0044458///motile cilium assembly+++GO:0090175///regulation of establishment of planar polarity+++GO:0090660///cerebrospinal fluid circulation 70997 70997 'Spef1' mRNA 879 816 841 21.83 19.95 22.15 3.82 4 3.17 21.31 3.663333333 177 181 142 845.3333333 166.6666667 2.30E-72 -2.355383896 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097542///ciliary tip+++GO:0097729///9+2 motile cilium+++GO:1990716///axonemal central apparatus GO:0003779///actin binding+++GO:0008017///microtubule binding "GO:0001578///microtubule bundle formation+++GO:0003341///cilium movement+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0016477///cell migration+++GO:0030030///cell projection organization+++GO:0030032///lamellipodium assembly+++GO:0046847///filopodium assembly+++GO:0051493///regulation of cytoskeleton organization+++GO:0060548///negative regulation of cell death+++GO:1904158///axonemal central apparatus assembly+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway" 70998 70998 'Phf6' mRNA 625 629 667 7.62 7.52 8.62 6.77 6.35 5.77 7.92 6.296666667 639 586 526 640.3333333 583.6666667 0.274144092 -0.148496034 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus" GO:0003677///DNA binding+++GO:0015631///tubulin binding+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0042826///histone deacetylase binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding+++GO:0051219///phosphoprotein binding+++GO:0097110///scaffold protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001835///blastocyst hatching+++GO:0006357///regulation of transcription by RNA polymerase II 70999 70999 'Naa40' mRNA 993 1079 1017 16.56 17.7 18 14.95 15.31 15.48 17.42 15.24666667 1029 1032 1033 1029.666667 1031.333333 0.939079083 -0.009314328 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034451///centriolar satellite "GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0043998///H2A histone acetyltransferase activity+++GO:1990189///peptide-serine-N-acetyltransferase activity" GO:0006474///N-terminal protein amino acid acetylation+++GO:0006629///lipid metabolic process+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation 71001 71001 'Mgat4e' mRNA 2 1 5 0.07 0.03 0.18 0 0 0 0.093333333 0 0 0 0 2.666666667 0 0.13597005 -3.902361769 "GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation 71003 71003 'Prss41' mRNA 195 206 168 10.38 11.09 9.74 4.09 3.01 3.66 10.40333333 3.586666667 89 61 77 189.6666667 75.66666667 2.63E-09 -1.336567723 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043229///intracellular organelle GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017080///sodium channel regulator activity GO:0006508///proteolysis 71007 71007 'D7Ertd443e' mRNA 553 566 532 8.85 9.21 9.47 1.73 1.34 1.9 9.176666667 1.656666667 117 86 118 550.3333333 107 5.03E-53 -2.375424976 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0016740///transferase activity+++GO:0042826///histone deacetylase binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0009411///response to UV+++GO:0010212///response to ionizing radiation+++GO:0016567///protein ubiquitination+++GO:0030308///negative regulation of cell growth+++GO:0046599///regulation of centriole replication+++GO:0050821///protein stabilization 71020 71020 'Spats1' mRNA 170.32 184 136 2.17 1.71 1.82 0.98 0.98 0.96 1.9 0.973333333 98 85.45 85 163.44 89.48333333 1.09E-04 -0.878340143 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71026 71026 'Speer3' mRNA 8 4 7 0.41 0.2 0.38 0.09 0.05 0.14 0.33 0.093333333 2 1 3 6.333333333 2 0.225290822 -1.682492407 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71027 71027 'Tmem30c' mRNA 17 38 27 0.31 0.78 0.63 0.01 0.15 0.05 0.573333333 0.07 2 11 4.01 27.33333333 5.67 0.002272964 -2.271149891 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0045332///phospholipid translocation 71041 71041 'Pcgf6' mRNA 339 290 150 10.65 10.23 4.21 3.04 5.59 5.67 8.363333333 4.766666667 134 220 233 259.6666667 195.6666667 0.170599576 -0.400927833 04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated" 71046 71046 '4933405L10Rik' mRNA 6 1 4 0.31 0.05 0.22 0.09 0.09 0.14 0.193333333 0.106666667 2 2 3 3.666666667 2.333333333 0.725458338 -0.670273602 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71059 71059 'Hexim2' mRNA 1213.7 1268.97 1142.44 11.36 11.09 11.22 6.14 6.36 5.78 11.22333333 6.093333333 706.21 675.19 660.07 1208.37 680.49 4.67E-22 -0.838760831 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0017069///snRNA binding+++GO:0042802///identical protein binding+++GO:0097322///7SK snRNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated" 71062 71062 'Tekt3' mRNA 96 142 93 3.2 4.66 3.28 0.03 0.18 0.09 3.713333333 0.1 1 6 3 110.3333333 3.333333333 3.93E-19 -5.051851847 GO:0002080///acrosomal membrane+++GO:0002081///outer acrosomal membrane+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0060378///regulation of brood size 71063 71063 'Zfp597' mRNA 405.67 416.94 390.78 3.93 3.96 4.01 2.59 2.57 2.57 3.966666667 2.576666667 305.67 296 295 404.4633333 298.89 0.001097336 -0.446024213 05168///Herpes simplex virus 1 infection GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 71069 71069 'Stox2' mRNA 2604.43 2646.46 2192.8 5.59 5.29 4.8 3 2.74 2.93 5.226666667 2.89 1751.81 1488.67 1757.77 2481.23 1666.083333 3.13E-13 -0.584287505 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function" GO:0001893///maternal placenta development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009617///response to bacterium+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0045944///positive regulation of transcription by RNA polymerase II 71085 71085 'Arhgap19' mRNA 2432 2624 2309 25.57 27.17 25.8 27.86 26.69 27.68 26.18 27.41 3048 2847 2937 2455 2944 1.07E-04 0.251353073 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction 71091 71091 'Cdkl1' mRNA 331.56 290.56 269.74 8.57 7.63 6.91 4.77 4.33 5.06 7.703333333 4.72 236.03 193.99 221.8 297.2866667 217.2733333 0.005783715 -0.464503694 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035869///ciliary transition zone+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle+++GO:1902017///regulation of cilium assembly 71093 71093 'Atoh8' mRNA 189 107 157 4.5 2.51 3.96 4.84 4.72 4.87 3.656666667 4.81 234 223 228 151 228.3333333 0.010870669 0.581045447 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0033613///activating transcription factor binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding" "GO:0001704///formation of primary germ layer+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0035148///tube formation+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051450///myoblast proliferation+++GO:0060395///SMAD protein signal transduction+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II" 71096 71096 'Sntg1' mRNA 4 8 1 0.04 0.08 0.01 0 0 0 0.043333333 0 0 0 0 4.333333333 0 0.040003273 -4.539890518 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0032587///ruffle membrane GO:0003779///actin binding+++GO:0005198///structural molecule activity+++GO:0008022///protein C-terminus binding 71099 71099 'Tssk4' mRNA 27.64 25 21.6 1.49 1.13 1.56 1.19 1.28 0.69 1.393333333 1.053333333 33.56 30.98 14.45 24.74666667 26.33 0.923114693 0.066509583 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0035556///intracellular signal transduction+++GO:1990443///peptidyl-threonine autophosphorylation 71101 71101 'Uvssa' mRNA 1017 1007 1061 7.17 7.04 8.01 3.98 4.02 4.08 7.406666667 4.026666667 641 636 642 1028.333333 639.6666667 1.36E-12 -0.698521245 GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0000993///RNA polymerase II complex binding GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0016567///protein ubiquitination 71103 71103 'Glt6d1' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0005975///carbohydrate metabolic process+++GO:0030259///lipid glycosylation 71111 71111 'Gpr39' mRNA 0 10.43 8.82 0 0.21 0.19 0.05 0 0 0.133333333 0.016666667 2.61 0 0 6.416666667 0.87 0.111284876 -3.205962025 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0046872///metal ion binding GO:0000187///activation of MAPK activity+++GO:0002024///diet induced thermogenesis+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008343///adult feeding behavior+++GO:0019216///regulation of lipid metabolic process+++GO:0030641///regulation of cellular pH+++GO:0032024///positive regulation of insulin secretion+++GO:0035483///gastric emptying+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042391///regulation of membrane potential+++GO:0042593///glucose homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0043406///positive regulation of MAP kinase activity+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060455///negative regulation of gastric acid secretion+++GO:0071294///cellular response to zinc ion 71116 71116 'Stx18' mRNA 691.56 706.74 693.39 21.42 22.7 22.66 22.77 23.86 22.75 22.26 23.12666667 839.18 820.53 775.74 697.23 811.8166667 0.050950118 0.207464778 04130///SNARE interactions in vesicular transport+++04145///Phagosome GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex GO:0005484///SNAP receptor activity+++GO:0019904///protein domain specific binding "GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0090158///endoplasmic reticulum membrane organization+++GO:1902117///positive regulation of organelle assembly+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport+++GO:1903358///regulation of Golgi organization" 71130 71130 'Sh2d6' mRNA 89 83 75 3.64 3.68 3.37 0.98 1.79 1.51 3.563333333 1.426666667 27 45 41 82.33333333 37.66666667 8.86E-04 -1.134337573 GO:0005737///cytoplasm GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction 71131 71131 'Zfp689' mRNA 285 280 249 4.27 4.13 3.96 2.21 2.71 2.81 4.12 2.576666667 170 203 209 271.3333333 194 0.00543594 -0.492199665 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035914///skeletal muscle cell differentiation" 71132 71132 'Cabyr' mRNA 32.45 41.51 29.46 1.2 1.49 1.07 0.87 0.86 0.73 1.253333333 0.82 25.49 26.58 22.99 34.47333333 25.02 0.349863462 -0.489511581 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0042995///cell projection+++GO:0097228///sperm principal piece+++GO:0097229///sperm end piece GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding GO:0019722///calcium-mediated signaling+++GO:0048240///sperm capacitation 71137 71137 'Rfx4' mRNA 52.8 30.13 32.52 0.44 0.24 0.29 0.14 0.17 0.15 0.323333333 0.153333333 20.17 21.49 19.98 38.48333333 20.54666667 0.06350294 -0.934654912 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021516///dorsal spinal cord development+++GO:0021537///telencephalon development+++GO:0021696///cerebellar cortex morphogenesis+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060271///cilium assembly+++GO:0070613///regulation of protein processing" 71138 71138 'Tmem217' mRNA 2 3 7 0.16 0.24 0.6 0.07 0.36 0.19 0.333333333 0.206666667 1 5 3 4 3 0.812362758 -0.440321039 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 71145 71145 'Scara5' mRNA 271 253 286 3.87 3.56 4.33 10.91 10.15 10.33 3.92 10.46333333 880 800 807 270 829 1.12E-41 1.603742516 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030666///endocytic vesicle membrane GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0070287///ferritin receptor activity GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0034605///cellular response to heat+++GO:0034755///iron ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0070207///protein homotrimerization 71146 71146 'Golga7b' mRNA 32 42 33 0.62 0.82 0.7 0.2 0.21 0.14 0.713333333 0.183333333 12 12 8 35.66666667 10.66666667 0.00124942 -1.751144686 GO:0000139///Golgi membrane+++GO:0002178///palmitoyltransferase complex+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0005515///protein binding+++GO:0019899///enzyme binding GO:0006612///protein targeting to membrane+++GO:0018215///protein phosphopantetheinylation+++GO:0018230///peptidyl-L-cysteine S-palmitoylation 71147 71147 'Oxsm' mRNA 89 73 50 1.1 0.9 0.64 0.88 0.87 1.16 0.88 0.97 80 78 96 70.66666667 84.66666667 0.478347733 0.257208013 00061///Fatty acid biosynthesis+++00780///Biotin metabolism+++01212///Fatty acid metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0004315///3-oxoacyl-[acyl-carrier-protein] synthase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006637///acyl-CoA metabolic process+++GO:0051790///short-chain fatty acid biosynthetic process+++GO:0051792///medium-chain fatty acid biosynthetic process 71148 71148 'Mier1' mRNA 1061 1021 993 12.07 11.35 11.96 11.02 10.47 11.45 11.79333333 10.98 1116 1043 1129 1025 1096 0.414921576 0.084764534 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016575///histone deacetylation+++GO:0031937///positive regulation of chromatin silencing" 71149 71149 'Tex52' mRNA 413 488 403 23.69 27.66 24.53 2.35 2.05 1.86 25.29333333 2.086666667 47 40 36 434.6666667 41 7.49E-66 -3.416588144 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71151 71151 'Eri2' mRNA 264.05 264.52 302.74 3.36 3.41 4.19 2.83 2.66 2.96 3.653333333 2.816666667 238.45 217.86 240.64 277.1033333 232.3166667 0.137210546 -0.271987461 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000738///DNA catabolic process, exonucleolytic" 71156 71156 'Lrrc72' mRNA 1 0 0 0.1 0 0 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71159 71159 '4933416I08Rik' mRNA 0 0 3 0 0 0.17 0.09 0.05 0 0.056666667 0.046666667 2 1 0 1 1 0.98725936 -0.086367047 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71162 71162 '4933421I07Rik' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 71163 71163 'Zfp626' mRNA 137.45 184.61 116.31 1.32 1.71 1.16 0.97 1.03 1.09 1.396666667 1.03 117.08 118.93 126.22 146.1233333 120.7433333 0.288454041 -0.280196232 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 71166 71166 '4933424G06Rik' mRNA 1 2 1 0.06 0.11 0.06 0.1 0.15 0.1 0.076666667 0.116666667 2 3 2 1.333333333 2.333333333 0.731311041 0.806534171 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 71169 71169 'Nbas' mRNA 1695 1626 1555 12.44 11.64 11.94 4.13 3.23 3.89 12.00666667 3.75 654 501 598 1625.333333 584.3333333 1.07E-54 -1.488932023 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0070939///Dsl1/NZR complex GO:0000149///SNARE binding "GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0015031///protein transport+++GO:2000623///negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 71175 71175 'Nipbl' mRNA 2869.98 2947.89 2531.59 15.03 15.29 14.19 11.01 9.63 10.45 14.83666667 10.36333333 2406.07 2059.78 2226.35 2783.153333 2230.733333 3.62E-06 -0.329528232 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0032039///integrator complex+++GO:0032116///SMC loading complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090694///Scc2-Scc4 cohesin loading complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0036033///mediator complex binding+++GO:0042826///histone deacetylase binding+++GO:0047485///protein N-terminus binding+++GO:0070087///chromo shadow domain binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003007///heart morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007605///sensory perception of sound+++GO:0010468///regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0031065///positive regulation of histone deacetylation+++GO:0034087///establishment of mitotic sister chromatid cohesion+++GO:0034088///maintenance of mitotic sister chromatid cohesion+++GO:0034613///cellular protein localization+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035136///forelimb morphogenesis+++GO:0035261///external genitalia morphogenesis+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042471///ear morphogenesis+++GO:0042634///regulation of hair cycle+++GO:0045444///fat cell differentiation+++GO:0045778///positive regulation of ossification+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045995///regulation of embryonic development+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048565///digestive tract development+++GO:0048589///developmental growth+++GO:0048592///eye morphogenesis+++GO:0048638///regulation of developmental growth+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0050890///cognition+++GO:0060325///face morphogenesis+++GO:0061010///gall bladder development+++GO:0061038///uterus morphogenesis+++GO:0061780///mitotic cohesin loading+++GO:0071169///establishment of protein localization to chromatin+++GO:0071481///cellular response to X-ray+++GO:0071733///transcriptional activation by promoter-enhancer looping+++GO:0071921///cohesin loading+++GO:1905406///positive regulation of mitotic cohesin loading+++GO:1990414///replication-born double-strand break repair via sister chromatid exchange+++GO:2001224///positive regulation of neuron migration" 71176 71176 'Fbxo24' mRNA 28 31 13 0.73 0.8 0.36 0.18 0.23 0.42 0.63 0.276666667 8 10 18 24 12 0.148995692 -0.994095633 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71177 71177 'Ints13' mRNA 632.16 793.89 750 11.01 13.84 14.03 13.02 11.99 12.25 12.96 12.42 833 755 752.27 725.35 780.09 0.520355015 0.091613116 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0032039///integrator complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0030317///flagellated sperm motility+++GO:0051301///cell division+++GO:0051642///centrosome localization+++GO:0080154///regulation of fertilization+++GO:0090435///protein localization to nuclear envelope 71183 71183 'Clec12b' mRNA 2 1 0 0.09 0.05 0 0 0.09 0 0.046666667 0.03 0 2 0 1 0.666666667 0.882891329 -0.54745474 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0019903///protein phosphatase binding+++GO:0030246///carbohydrate binding+++GO:0030545///receptor regulator activity+++GO:0030547///receptor inhibitor activity GO:0002769///natural killer cell inhibitory signaling pathway+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:2000272///negative regulation of signaling receptor activity 71198 71198 'Otud1' mRNA 274 247 130 4.2 3.72 2.11 2.02 1.84 2.27 3.343333333 2.043333333 152 135 165 217 150.6666667 0.039320993 -0.525467352 GO:0005575///cellular_component GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0070536///protein K63-linked deubiquitination 71200 71200 'Dydc2' mRNA 155 162.56 157.87 10.75 11.16 11.1 2.79 4.24 3.88 11.00333333 3.636666667 49 66 59 158.4766667 58 3.41E-09 -1.455969839 "GO:0000781///chromosome, telomeric region+++GO:0044666///MLL3/4 complex+++GO:0048188///Set1C/COMPASS complex" GO:0006348///chromatin silencing at telomere+++GO:0031509///telomeric heterochromatin assembly+++GO:0051568///histone H3-K4 methylation 71206 71206 'Katnal2' mRNA 443 432 449 11.64 10.82 11.53 2.28 2.72 2.12 11.33 2.373333333 107 103 95 441.3333333 101.6666667 6.32E-40 -2.13157927 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0016853///isomerase activity+++GO:0016887///ATPase activity GO:0031122///cytoplasmic microtubule organization+++GO:0051013///microtubule severing 71207 71207 'Nudt4' mRNA 2797 2857 1954 47.63 47.87 35.3 26.31 29.14 30.17 43.6 28.54 1778 1923 1974 2536 1891.666667 5.45E-05 -0.425624037 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000298///endopolyphosphatase activity+++GO:0003723///RNA binding+++GO:0008486///diphosphoinositol-polyphosphate diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0030515///snoRNA binding+++GO:0034431///bis(5'-adenosyl)-hexaphosphatase activity+++GO:0034432///bis(5'-adenosyl)-pentaphosphatase activity+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0052840///inositol diphosphate tetrakisphosphate diphosphatase activity+++GO:0052842///inositol diphosphate pentakisphosphate diphosphatase activity GO:0071543///diphosphoinositol polyphosphate metabolic process+++GO:1901907///diadenosine pentaphosphate catabolic process+++GO:1901909///diadenosine hexaphosphate catabolic process+++GO:1901911///adenosine 5'-(hexahydrogen pentaphosphate) catabolic process 71213 71213 'Cage1' mRNA 88 62.16 70 1.61 1.21 1.31 0.54 0.41 0.32 1.376666667 0.423333333 31 25.07 21 73.38666667 25.69 4.06E-05 -1.528450374 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71223 71223 'Gpr15' mRNA 0 1 3 0 0.02 0.08 0.44 0.29 0.27 0.033333333 0.333333333 20 13 12 1.333333333 15 0.002415345 3.459250294 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001618///virus receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0015026///coreceptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0046718///viral entry into host cell+++GO:0072678///T cell migration 71227 71227 'Daw1' mRNA 57 41 39 1.94 1.37 1.45 0.07 0.06 0.04 1.586666667 0.056666667 2 2 1 45.66666667 1.666666667 4.19E-09 -4.785066488 GO:0005576///extracellular region+++GO:0019005///SCF ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0000209///protein polyubiquitination+++GO:0003351///epithelial cilium movement+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0036158///outer dynein arm assembly+++GO:0051649///establishment of localization in cell+++GO:0090660///cerebrospinal fluid circulation 71228 71228 'Dlg5' mRNA 796 857 759 5.61 6.05 5.75 2.66 2.25 2.59 5.803333333 2.5 427 357 396 804 393.3333333 1.01E-21 -1.043013132 04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008092///cytoskeletal protein binding GO:0001837///epithelial to mesenchymal transition+++GO:0030011///maintenance of cell polarity+++GO:0030336///negative regulation of cell migration+++GO:0030859///polarized epithelial cell differentiation+++GO:0030901///midbrain development+++GO:0035331///negative regulation of hippo signaling+++GO:0035332///positive regulation of hippo signaling+++GO:0042130///negative regulation of T cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0045176///apical protein localization+++GO:0045186///zonula adherens assembly+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051965///positive regulation of synapse assembly+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060999///positive regulation of dendritic spine development+++GO:0065003///protein-containing complex assembly+++GO:0071896///protein localization to adherens junction+++GO:0072205///metanephric collecting duct development 71233 71233 'Enkur' mRNA 712 757 680 36.48 38.3 36.96 4.82 5.26 5.36 37.24666667 5.146666667 108 115 116 716.3333333 113 9.99E-85 -2.674568328 GO:0001669///acrosomal vesicle+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097228///sperm principal piece+++GO:0097728///9+0 motile cilium+++GO:0097729///9+2 motile cilium GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0017124///SH3 domain binding GO:0030317///flagellated sperm motility+++GO:0061966///establishment of left/right asymmetry 71236 71236 'Rsph14' mRNA 122 148 161 6.2 7.48 8.72 0.31 0.6 0.51 7.466666667 0.473333333 7 13 11 143.6666667 10.33333333 3.37E-24 -3.811750441 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71238 71238 'Sdhaf3' mRNA 149 148 178 14.45 13.42 18.86 13.14 12.89 11.12 15.57666667 12.38333333 150 153 137 158.3333333 146.6666667 0.643007655 -0.126686451 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix GO:0003674///molecular_function GO:0006105///succinate metabolic process+++GO:0034553///mitochondrial respiratory chain complex II assembly 71240 71240 'Osbpl7' mRNA 624 612 578 9.51 9.06 9.17 6.61 6.85 6.7 9.246666667 6.72 509 510 494 604.6666667 504.3333333 0.018060356 -0.272741555 GO:0005654///nucleoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0097038///perinuclear endoplasmic reticulum GO:0008289///lipid binding+++GO:0015485///cholesterol binding GO:0006869///lipid transport+++GO:0071397///cellular response to cholesterol+++GO:1901800///positive regulation of proteasomal protein catabolic process 71242 71242 'Spata24' mRNA 95 114 138 9.56 11.38 14.73 9.6 8.16 7.01 11.89 8.256666667 109 90 77 115.6666667 92 0.248585765 -0.350614223 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 71254 71254 'Naif1' mRNA 252.77 234.63 268.01 4.36 3.98 4.9 3.61 3.62 3.26 4.413333333 3.496666667 240.58 235.71 210.58 251.8033333 228.9566667 0.454032054 -0.153480532 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0030308///negative regulation of cell growth+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process 71263 71263 'Mro' mRNA 114.21 120.28 111.08 2.26 2.44 2.33 3.13 2.81 3.17 2.343333333 3.036666667 162.51 143.96 156.65 115.19 154.3733333 0.072822357 0.406277291 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 71268 71268 'Lrrfip2' mRNA 986 979 730 18.1 18.21 14.65 12.82 17.21 17.56 16.98666667 15.86333333 751 980 1007 898.3333333 912.6666667 0.908559013 0.019911266 GO:0005515///protein binding+++GO:0030275///LRR domain binding "GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035660///MyD88-dependent toll-like receptor 4 signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity" 71275 71275 'Noxred1' mRNA 11 12 21 0.46 0.5 0.94 0.59 0.49 0.76 0.633333333 0.613333333 16 13 20 14.66666667 16.33333333 0.873828097 0.129480505 GO:0005575///cellular_component GO:0004735///pyrroline-5-carboxylate reductase activity+++GO:0016491///oxidoreductase activity GO:0006561///proline biosynthetic process+++GO:0055129///L-proline biosynthetic process 71276 71276 'Ccdc57' mRNA 449 481 447 7.14 7.56 7.54 2.49 2.16 2.97 7.413333333 2.54 179 152 207 459 179.3333333 2.12E-19 -1.367853512 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007020///microtubule nucleation+++GO:0007099///centriole replication+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0060271///cilium assembly 71279 71279 'Slc29a3' mRNA 714 679.37 775 9.83 8.47 11.65 18.93 18.28 18.76 9.983333333 18.65666667 1637.61 1543 1540 722.79 1573.536667 1.16E-31 1.107087743 05034///Alcoholism GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005337///nucleoside transmembrane transporter activity GO:0015858///nucleoside transport+++GO:1901642///nucleoside transmembrane transport 71281 71281 'Apobec4' mRNA 6 3 2 0.22 0.11 0.08 0 0 0 0.136666667 0 0 0 0 3.666666667 0 0.059134443 -4.316081978 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0008150///biological_process 71287 71287 'Cpvl' mRNA 32 37 36 1.38 1.57 1.67 0.63 0.67 0.47 1.54 0.59 17 18 12 35 15.66666667 0.02317315 -1.172697617 GO:0004180///carboxypeptidase activity+++GO:0004185///serine-type carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 71300 71300 'Rnf148' mRNA 3 4 3 0.15 0.19 0.16 0 0.04 0 0.166666667 0.013333333 0 1 0 3.333333333 0.333333333 0.154168943 -3.226041862 GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination 71302 71302 'Arhgap26' mRNA 2595.84 2595.57 2498.57 29.37 29.23 30.47 22.01 21.1 24.55 29.69 22.55333333 2190 1838.43 2164.29 2563.326667 2064.24 2.81E-05 -0.325149195 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding GO:0007165///signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction 71306 71306 'Mfap3l' mRNA 674 655 638 5.61 5.36 5.63 5.05 5.02 5.1 5.533333333 5.056666667 696 679 685 655.6666667 686.6666667 0.685084116 0.054956909 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function GO:0008150///biological_process 71310 71310 'Tbc1d9' mRNA 449 449 263 4.09 4.05 2.63 2.29 2.63 2.94 3.59 2.62 271 303 347 387 307 0.097493596 -0.333628879 GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0090630///activation of GTPase activity 71313 71313 'Fsip1' mRNA 113 110 98 3.36 3.12 3.19 0.37 0.51 0.24 3.223333333 0.373333333 16 20 9 107 15 8.41E-15 -2.843791306 GO:0031514///motile cilium GO:0005515///protein binding GO:0008150///biological_process 71323 71323 'Rassf8' mRNA 130 143 118 1.28 1.38 1.23 1.49 1.33 1.57 1.296666667 1.463333333 176 152 180 130.3333333 169.3333333 0.095220184 0.367638269 GO:0007165///signal transduction 71326 71326 'Treml1' mRNA 2 1 0 0.1 0.05 0 0.26 0.22 0.09 0.05 0.19 6 5 2 1 4.333333333 0.253400659 2.119561496 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck+++GO:0031091///platelet alpha granule GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0009968///negative regulation of signal transduction+++GO:0019722///calcium-mediated signaling+++GO:0030168///platelet activation+++GO:0042060///wound healing 71330 71330 'Rcbtb1' mRNA 1496 1657 1103 21.07 22.61 16.32 16.07 18.12 16.45 20 16.88 1322 1461 1329 1418.666667 1370.666667 0.730544595 -0.052634002 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0006325///chromatin organization+++GO:0007049///cell cycle 71336 71336 'Rbks' mRNA 171 159 137 10.47 9.61 8.83 9.94 9.56 9.94 9.636666667 9.813333333 190 175 180 155.6666667 181.6666667 0.335863892 0.213375894 00030///Pentose phosphate pathway GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0004747///ribokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006014///D-ribose metabolic process+++GO:0016310///phosphorylation+++GO:0019303///D-ribose catabolic process+++GO:0046835///carbohydrate phosphorylation 71338 71338 'Tprg' mRNA 0 1 0 0 0.06 0 0 0.05 0 0.02 0.016666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 71340 71340 'Riok1' mRNA 364 440.84 394 7.5 9.4 9.08 9.28 9.63 9.12 8.66 9.343333333 493 504.93 475 399.6133333 490.9766667 0.036082073 0.285951036 03008///Ribosome biogenesis in eukaryotes "GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030688///preribosome, small subunit precursor+++GO:0034708///methyltransferase complex" GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis+++GO:0042274///ribosomal small subunit biogenesis+++GO:2000234///positive regulation of rRNA processing 71345 71345 'Ano9' mRNA 43 39 56 0.85 0.79 1.17 1.28 1.43 1.44 0.936666667 1.383333333 79 85 86 46 83.33333333 0.011085068 0.839558146 GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0017128///phospholipid scramblase activity GO:0006821///chloride transport+++GO:0006869///lipid transport+++GO:0055085///transmembrane transport+++GO:0061588///calcium activated phospholipid scrambling+++GO:0061589///calcium activated phosphatidylserine scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:1902476///chloride transmembrane transport+++GO:1902939///negative regulation of intracellular calcium activated chloride channel activity 71354 71354 'Wdr31' mRNA 1711.35 1646.57 1599.54 40.99 38.79 40.51 14.96 13.85 15.28 40.09666667 14.69666667 717.04 649.51 704.45 1652.486667 690.3333333 3.70E-53 -1.271699769 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71355 71355 'Col24a1' mRNA 47 47 40 0.36 0.36 0.34 0.36 0.28 0.3 0.353333333 0.313333333 56 42 43 44.66666667 47 0.893879575 0.061904803 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0001525///angiogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0030198///extracellular matrix organization 71361 71361 'Aifm2' mRNA 442.36 483.86 434.83 8.88 9.38 9.42 12.52 12.81 11.52 9.226666667 12.28333333 657.48 600.47 574.58 453.6833333 610.8433333 3.52E-04 0.418476887 04115///p53 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0003677///DNA binding+++GO:0004174///electron-transferring-flavoprotein dehydrogenase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016655///oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor+++GO:0050660///flavin adenine dinucleotide binding" GO:0006743///ubiquinone metabolic process+++GO:0008637///apoptotic mitochondrial changes+++GO:0022904///respiratory electron transport chain+++GO:0043065///positive regulation of apoptotic process+++GO:0110076///negative regulation of ferroptosis+++GO:1900407///regulation of cellular response to oxidative stress 71365 71365 'Pdss2' mRNA 395 376 438 7.56 7.48 9.48 5.22 7.28 7.38 8.173333333 6.626666667 294 333 369 403 332 0.077567323 -0.293785704 00900///Terpenoid backbone biosynthesis GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:1990234///transferase complex GO:0000010///trans-hexaprenyltranstransferase activity+++GO:0004659///prenyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046982///protein heterodimerization activity+++GO:0050347///trans-octaprenyltranstransferase activity+++GO:0097269///all-trans-decaprenyl-diphosphate synthase activity GO:0006744///ubiquinone biosynthetic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0021549///cerebellum development+++GO:0050878///regulation of body fluid levels 71367 71367 'Chst9' mRNA 535 595 531 16.08 17.61 16.91 3.54 3.16 4.12 16.86666667 3.606666667 134 118 152 553.6666667 134.6666667 5.06E-44 -2.050818153 00513///Various types of N-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001537///N-acetylgalactosamine 4-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0030166///proteoglycan biosynthetic process 71371 71371 'Arid5b' mRNA 978 925 953 9.72 9.18 10.14 19.79 17.84 18.14 9.68 18.59 2279 1961 2011 952 2083.666667 1.11E-41 1.116139079 GO:0005634///nucleus GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006807///nitrogen compound metabolic process+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0010761///fibroblast migration+++GO:0030325///adrenal gland development+++GO:0035264///multicellular organism growth+++GO:0045444///fat cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048468///cell development+++GO:0048644///muscle organ morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0060612///adipose tissue development+++GO:0060613///fat pad development+++GO:1990830///cellular response to leukemia inhibitory factor" 71373 71373 'Prr16' mRNA 71 95 24 1.8 2.37 0.64 1.3 1.98 1.98 1.603333333 1.753333333 59 88 87 63.33333333 78 0.525169399 0.314694829 GO:0005575///cellular_component GO:0003674///molecular_function GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size 71375 71375 'Foxn3' mRNA 1034 921.98 725.93 13.15 12.06 9.44 9.88 13 11.63 11.55 11.50333333 1027 1140.91 1098.98 893.97 1088.963333 0.017850589 0.279691005 GO:0005634///nucleus GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008022///protein C-terminus binding+++GO:0043565///sequence-specific DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0097094///craniofacial suture morphogenesis" 71382 71382 'Pex1' mRNA 282.26 301.09 325.38 3.46 3.73 4.23 3 2.67 2.7 3.806666667 2.79 280.51 244.16 246.08 302.91 256.9166667 0.148789359 -0.253584411 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0016887///ATPase activity+++GO:0044877///protein-containing complex binding GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix+++GO:0060152///microtubule-based peroxisome localization 71386 71386 'Krtap28-13' mRNA 0 0 1 0 0 0.07 0.11 0.06 0.06 0.023333333 0.076666667 2 1 1 0.333333333 1.333333333 0.580448874 1.877282476 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71389 71389 'Chd6' mRNA 1750 1755 1712 8.67 8.54 8.99 6.03 5.75 5.76 8.733333333 5.846666667 1402 1307 1296 1739 1335 2.37E-07 -0.393964108 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0000166///nucleotide binding+++GO:0001221///transcription cofactor binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity GO:0006325///chromatin organization+++GO:0032508///DNA duplex unwinding+++GO:0036091///positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress 71393 71393 'Kctd6' mRNA 1181 1276 557 40.93 43.86 20.24 14.94 18.01 19.24 35.01 17.39666667 505 581 605 1004.666667 563.6666667 0.026481952 -0.82635362 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0031430///M band GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0097602///cullin family protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0040008///regulation of growth+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0051260///protein homooligomerization 71395 71395 'Cdcp3' mRNA 189 171 169 1.97 2.01 2.13 3.5 3.87 3.97 2.036666667 3.78 358 364 353 176.3333333 358.3333333 4.18E-11 1.011975053 04970///Salivary secretion GO:0005576///extracellular region+++GO:0016020///membrane GO:0005044///scavenger receptor activity GO:0006897///endocytosis+++GO:0008150///biological_process+++GO:0015031///protein transport+++GO:0030154///cell differentiation 71398 71398 'Tasl' mRNA 14.01 16.99 10 0.21 0.28 0.2 3 2.68 2.82 0.23 2.833333333 189 152 169 13.66666667 170 8.68E-29 3.662719654 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0036020///endolysosome membrane GO:0003674///molecular_function GO:0002376///immune system process+++GO:0034121///regulation of toll-like receptor signaling pathway+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0034161///positive regulation of toll-like receptor 8 signaling pathway+++GO:0035751///regulation of lysosomal lumen pH+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response 71405 71405 'Fam83c' mRNA 2 0 2 0.05 0 0.05 0.08 0 0.02 0.033333333 0.033333333 4 0 1 1.333333333 1.666666667 0.924637684 0.269754707 GO:0005575///cellular_component GO:0019901///protein kinase binding GO:0007165///signal transduction 71406 71406 'Spaar' mRNA 42 42 39 0.55 0.55 0.55 0.6 0.56 0.57 0.55 0.576666667 52 48 48 41 49.33333333 0.567979954 0.255535822 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0046611///lysosomal proton-transporting V-type ATPase complex+++GO:1905103///integral component of lysosomal membrane GO:0043416///regulation of skeletal muscle tissue regeneration+++GO:0071230///cellular response to amino acid stimulus+++GO:1904262///negative regulation of TORC1 signaling 71409 71409 'Fmnl2' mRNA 557.8 528.98 521.14 5.39 5.11 5.41 4.95 3.8 4.94 5.303333333 4.563333333 582.86 441.12 553.52 535.9733333 525.8333333 0.821546494 -0.040903833 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003779///actin binding+++GO:0031267///small GTPase binding+++GO:0051015///actin filament binding GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape+++GO:0016043///cellular component organization+++GO:0016477///cell migration+++GO:0022604///regulation of cell morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030866///cortical actin cytoskeleton organization 71412 71412 'Dhrs2' mRNA 25 16 22 1.29 0.89 1.25 0.44 0.43 0.25 1.143333333 0.373333333 9 9 5 21 7.666666667 0.038242952 -1.469768165 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0004090///carbonyl reductase (NADPH) activity+++GO:0016491///oxidoreductase activity GO:0009636///response to toxic substance+++GO:0022900///electron transport chain+++GO:0034599///cellular response to oxidative stress+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043066///negative regulation of apoptotic process 71421 71421 'Amtn' mRNA 16 13 12 1 0.8 0.79 0.05 0.06 0.06 0.863333333 0.056666667 1 1 1 13.66666667 1 0.001888072 -3.78169817 GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005911///cell-cell junction+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0031214///biomineral tissue development+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0070169///positive regulation of biomineral tissue development+++GO:0070175///positive regulation of enamel mineralization 71425 71425 'Bpifb9a' mRNA 2 2 2 0.06 0.05 0.06 0 0 0 0.056666667 0 0 0 0 2 0 0.24179477 -3.455264535 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0007608///sensory perception of smell+++GO:0008150///biological_process 71435 71435 'Arhgap21' mRNA 1664.65 1671.41 1564.92 9.67 9.81 9.7 7.67 6.82 7.34 9.726666667 7.276666667 1559.33 1381.28 1497.13 1633.66 1479.246667 0.058496678 -0.154804108 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity GO:0007030///Golgi organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051645///Golgi localization+++GO:0051683///establishment of Golgi localization+++GO:0051684///maintenance of Golgi location+++GO:0072384///organelle transport along microtubule 71436 71436 'Flrt3' mRNA 634 622 652 8.49 8.2 9.29 4.51 4.39 4.22 8.66 4.373333333 387 368 352 636 369 1.71E-11 -0.799220497 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005925///focal adhesion+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0032584///growth cone membrane+++GO:0042995///cell projection+++GO:0043679///axon terminus+++GO:0044295///axonal growth cone+++GO:0097060///synaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0045499///chemorepellent activity GO:0003345///proepicardium cell migration involved in pericardium morphogenesis+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0007416///synapse assembly+++GO:0007507///heart development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0031175///neuron projection development+++GO:0048598///embryonic morphogenesis+++GO:0048678///response to axon injury+++GO:0050808///synapse organization+++GO:0050919///negative chemotaxis+++GO:0051965///positive regulation of synapse assembly+++GO:0060322///head development+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0099560///synaptic membrane adhesion+++GO:1990138///neuron projection extension 71446 71446 'Get1' mRNA 1495 1606 1611 33.29 35.21 38.05 19.55 20.1 20 35.51666667 19.88333333 1010 1014 1000 1570.666667 1008 3.23E-14 -0.653031335 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043529///GET complex GO:0003674///molecular_function GO:0001964///startle response+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0007605///sensory perception of sound+++GO:0045048///protein insertion into ER membrane+++GO:0050808///synapse organization+++GO:0050821///protein stabilization+++GO:0071599///otic vesicle development+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 71448 71448 'Tmem80' mRNA 519 520 434 17.11 16.9 15.41 12.51 11.05 12.58 16.47333333 12.04666667 448 378 430 491 418.6666667 0.07680336 -0.239684445 GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection GO:0003674///molecular_function GO:1905515///non-motile cilium assembly 71449 71449 'Eef1aknmt' mRNA 288 295 275 5.84 5.94 5.88 6.11 5.24 5.63 5.886666667 5.66 347 289 311 286 315.6666667 0.46553741 0.129932407 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008152///metabolic process+++GO:0032259///methylation+++GO:1902807///negative regulation of cell cycle G1/S phase transition 71452 71452 'Ankrd40' mRNA 536 524 586 8.53 8.07 9.72 9.92 9.35 9.26 8.773333333 9.51 725 672 660 548.6666667 685.6666667 0.011668527 0.306233723 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71458 71458 'Bcor' mRNA 346 321 306 2.9 2.64 2.66 2.02 2.06 2.35 2.733333333 2.143333333 279 278 314 324.3333333 290.3333333 0.318378516 -0.170253827 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0140261///BCOR complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0031072///heat shock protein binding+++GO:0042826///histone deacetylase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000415///negative regulation of histone H3-K36 methylation+++GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0007507///heart development+++GO:0030502///negative regulation of bone mineralization+++GO:0035518///histone H2A monoubiquitination+++GO:0042476///odontogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0060021///roof of mouth development+++GO:0065001///specification of axis polarity+++GO:0070171///negative regulation of tooth mineralization" 71461 71461 'Ptk7' mRNA 1029 914 928 13.37 11.74 12.94 12.71 11.27 10.51 12.68333333 11.49666667 1124 969 904 957 999 0.731311041 0.048586825 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0050839///cell adhesion molecule binding GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0001843///neural tube closure+++GO:0003281///ventricular septum development+++GO:0003401///axis elongation+++GO:0006468///protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007507///heart development+++GO:0010976///positive regulation of neuron projection development+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0031532///actin cytoskeleton reorganization+++GO:0042060///wound healing+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0060026///convergent extension+++GO:0060484///lung-associated mesenchyme development+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0060976///coronary vasculature development+++GO:0071300///cellular response to retinoic acid+++GO:0090103///cochlea morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090263///positive regulation of canonical Wnt signaling pathway 71472 71472 'Usp19' mRNA 4011 3965 3028 44.13 43.24 35.49 25.14 27.11 26.26 40.95333333 26.17 2629 2769 2653 3668 2683.666667 3.17E-08 -0.45623528 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0051879///Hsp90 protein binding+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0031647///regulation of protein stability+++GO:0034976///response to endoplasmic reticulum stress+++GO:0048642///negative regulation of skeletal muscle tissue development+++GO:0050821///protein stabilization+++GO:0071108///protein K48-linked deubiquitination+++GO:0090068///positive regulation of cell cycle process+++GO:1900037///regulation of cellular response to hypoxia+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:1904292///regulation of ERAD pathway 71474 71474 'Ppp6r2' mRNA 1178 958 1084 16.76 13.42 16.66 9.39 9.06 10.6 15.61333333 9.683333333 741 737 822 1073.333333 766.6666667 7.63E-06 -0.498731529 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0019888///protein phosphatase regulator activity+++GO:0019903///protein phosphatase binding GO:0006516///glycoprotein catabolic process+++GO:0043666///regulation of phosphoprotein phosphatase activity 71481 71481 'Alpk1' mRNA 241 253 187 1.98 2.07 1.55 1.88 1.73 1.74 1.866666667 1.783333333 235 208 207 227 216.6666667 0.750319743 -0.074861678 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0048029///monosaccharide binding GO:0002376///immune system process+++GO:0002753///cytoplasmic pattern recognition receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0009617///response to bacterium+++GO:0016310///phosphorylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0060271///cilium assembly 71492 71492 'Bbs7' mRNA 465 433 465 9.93 9.11 10.54 4.83 4.14 4.66 9.86 4.543333333 260 218 243 454.3333333 240.3333333 4.25E-11 -0.933365086 GO:0001750///photoreceptor outer segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0034464///BBSome+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0060170///ciliary membrane GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0001654///eye development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045444///fat cell differentiation+++GO:0046907///intracellular transport+++GO:0060173///limb development+++GO:0060271///cilium assembly+++GO:1903929///primary palate development+++GO:1905515///non-motile cilium assembly 71508 71508 'Zfp935' mRNA 281.11 321.88 263.79 6.35 7.16 6.31 6.37 5.4 4.39 6.606666667 5.386666667 324.39 267.5 216.74 288.9266667 269.5433333 0.615074532 -0.111486399 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 71514 71514 'Sfpq' mRNA 2092.38 1878.04 1976.24 12.69 12.39 12.43 12.3 13.12 13.31 12.50333333 12.91 1969.21 1831.89 1977.68 1982.22 1926.26 0.587819295 -0.054839491 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0032839///dendrite cytoplasm+++GO:0042382///paraspeckles+++GO:0090575///RNA polymerase II transcription factor complex GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000724///double-strand break repair via homologous recombination+++GO:0002218///activation of innate immune response+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008380///RNA splicing+++GO:0042752///regulation of circadian rhythm+++GO:0042754///negative regulation of circadian rhythm+++GO:0045087///innate immune response+++GO:0045876///positive regulation of sister chromatid cohesion+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0051276///chromosome organization+++GO:0051726///regulation of cell cycle+++GO:0070932///histone H3 deacetylation+++GO:0098963///dendritic transport of messenger ribonucleoprotein complex+++GO:1902177///positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway" 71517 71517 'Vps35l' mRNA 1196 1341 1211 18.16 20.02 19.5 27.27 25.44 23.44 19.22666667 25.38333333 2067 1884 1721 1249.333333 1890.666667 6.33E-12 0.585597897 "GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030906///retromer, cargo-selective complex" GO:0003674///molecular_function "GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi" 71519 71519 'Cyp2u1' mRNA 207 229 189 4.98 5.42 4.82 1.94 2.38 2.51 5.073333333 2.276666667 93 111 116 208.3333333 106.6666667 2.00E-06 -0.973373863 00071///Fatty acid degradation+++00590///Arachidonic acid metabolism GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0052869///arachidonic acid omega-hydroxylase activity+++GO:0102033///fatty acid omega-hydroxylase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0097267///omega-hydroxylase P450 pathway 71520 71520 'Grap' mRNA 123 159 161 4.5 5.75 6.26 20.69 21.17 19.77 5.503333333 20.54333333 648 645 599 147.6666667 630.6666667 1.20E-45 2.080762939 GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098793///presynapse GO:0007605///sensory perception of sound 71521 71521 'Pds5a' mRNA 804 786 745 6.41 5.91 6.04 5.91 5.07 5.96 6.12 5.646666667 840 714 828 778.3333333 794 0.899676168 0.01659254 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane GO:0001656///metanephros development+++GO:0002088///lens development in camera-type eye+++GO:0003007///heart morphogenesis+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008156///negative regulation of DNA replication+++GO:0009952///anterior/posterior pattern specification+++GO:0051301///cell division+++GO:0060021///roof of mouth development+++GO:0097402///neuroblast migration 71522 71522 'Ggt6' mRNA 22 14 15 0.66 0.43 0.43 0.73 0.85 0.62 0.506666667 0.733333333 27 33 22 17 27.33333333 0.259305645 0.676378769 00430///Taurine and hypotaurine metabolism+++00480///Glutathione metabolism GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016787///hydrolase activity+++GO:0036374///glutathione hydrolase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0103068///leukotriene C4 gamma-glutamyl transferase activity" GO:0006508///proteolysis+++GO:0006749///glutathione metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0008150///biological_process 71529 71529 'Kazn' mRNA 794.9 742.66 423.54 9.94 9.27 5.6 4.22 3.63 4.16 8.27 4.003333333 367.91 310.49 357.41 653.7 345.27 1.25E-07 -0.92270889 GO:0001533///cornified envelope+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0030057///desmosome GO:0031424///keratinization 71532 71532 'Fam217b' mRNA 118.9 147.24 124.97 2.52 3.12 2.75 2.19 2.02 1.91 2.796666667 2.04 119.97 111.5 105.39 130.37 112.2866667 0.397047187 -0.226585248 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 71538 71538 'Fbxo9' mRNA 2235 2310 2287 61.12 62.79 66.75 35.09 35.68 33.92 63.55333333 34.89666667 1442 1454 1368 2277.333333 1421.333333 1.93E-20 -0.692685731 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0032006///regulation of TOR signaling+++GO:0045087///innate immune response+++GO:0045444///fat cell differentiation 71544 71544 'Arhgap42' mRNA 374 382 329 4.92 5.9 4.69 5.06 4.38 5.06 5.17 4.833333333 386 342 377 361.6666667 368.3333333 0.928752297 0.016121341 GO:0005096///GTPase activator activity GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0007165///signal transduction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0090630///activation of GTPase activity+++GO:1904694///negative regulation of vascular smooth muscle contraction 71562 71562 'Afmid' mRNA 165.64 130.52 113.54 2.8 2.31 2.59 3.24 3.24 2.24 2.566666667 2.906666667 188.38 166.79 134.16 136.5666667 163.11 0.339425645 0.249052195 00380///Tryptophan metabolism+++00630///Glyoxylate and dicarboxylate metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004061///arylformamidase activity+++GO:0016787///hydrolase activity GO:0006569///tryptophan catabolic process+++GO:0019441///tryptophan catabolic process to kynurenine+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan 71564 71564 'Izumo4' mRNA 1077.14 1040.96 982.91 53.54 54.11 55.1 23.34 26.55 29.14 54.25 26.34333333 564.63 582.6 638.12 1033.67 595.1166667 2.01E-16 -0.807077046 GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 71566 71566 'Clmp' mRNA 408 389 277 5.3 4.97 3.82 4.69 5.17 5.46 4.696666667 5.106666667 415 447 468 358 443.3333333 0.056529567 0.304265643 GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function GO:0048565///digestive tract development 71567 71567 'Mcm9' mRNA 306.25 259.77 156.35 3.4 2.89 1.77 1.68 2.12 2.05 2.686666667 1.95 182.37 226.58 206.59 240.79 205.18 0.371297101 -0.230484264 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0042555///MCM complex+++GO:0097362///MCM8-MCM9 complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding+++GO:0003697///single-stranded DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding+++GO:0032406///MutLbeta complex binding+++GO:0032407///MutSalpha complex binding+++GO:0032408///MutSbeta complex binding+++GO:0044877///protein-containing complex binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007276///gamete generation+++GO:0007292///female gamete generation+++GO:0032508///DNA duplex unwinding+++GO:0036298///recombinational interstrand cross-link repair+++GO:0070716///mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication+++GO:0071168///protein localization to chromatin 71583 71583 '9130008F23Rik' mRNA 170 216 197 4.45 5.57 5.47 4.48 3.82 3.85 5.163333333 4.05 197 164 164 194.3333333 175 0.48218406 -0.164890469 GO:0005575///cellular_component GO:0003674///molecular_function GO:0001835///blastocyst hatching 71584 71584 'Gdpd2' mRNA 13 4 4 0.3 0.09 0.1 0.59 0.96 0.83 0.163333333 0.793333333 30 48 42 7 40 4.01E-05 2.513706364 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030027///lamellipodium GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047394///glycerophosphoinositol inositolphosphodiesterase activity GO:0006629///lipid metabolic process+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0090527///actin filament reorganization 71586 71586 'Ifih1' mRNA 696 647 629 6.71 6.13 6.43 12.8 12.46 11.91 6.423333333 12.39 1528 1451 1377 657.3333333 1452 2.14E-38 1.131676292 04622///RIG-I-like receptor signaling pathway+++05161///Hepatitis B+++05162///Measles+++05164///Influenza A+++05168///Herpes simplex virus 1 infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0009615///response to virus+++GO:0016925///protein sumoylation+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0039530///MDA-5 signaling pathway+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0071360///cellular response to exogenous dsRNA+++GO:0098586///cellular response to virus 71591 71591 'Zfp251' mRNA 535 466 505 8.28 7.09 8.29 6.08 5.77 5.53 7.886666667 5.793333333 452 419 398 502 423 0.056451174 -0.260765548 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0061484///hematopoietic stem cell homeostasis" 71592 71592 'Pogk' mRNA 1144.37 1219.43 1129.94 7.66 7.96 8.06 5.75 4.87 4.92 7.893333333 5.18 975.48 817.35 821.48 1164.58 871.4366667 5.40E-06 -0.431202409 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003677///DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0008150///biological_process" 71599 71599 'Senp8' mRNA 375 358 328 5.48 5.11 5.05 3.7 2.95 2.97 5.213333333 3.206666667 291 231 227 353.6666667 249.6666667 0.001013887 -0.514580563 GO:0005634///nucleus GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016929///SUMO-specific protease activity+++GO:0019784///NEDD8-specific protease activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation 71602 71602 'Myo1e' mRNA 2584.51 2835.95 2809.43 28.5 30.52 32.4 24.35 24.69 23.94 30.47333333 24.32666667 2535.32 2507.57 2388.65 2743.296667 2477.18 0.046943561 -0.160507085 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0016459///myosin complex+++GO:0030054///cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032437///cuticular plate+++GO:0032991///protein-containing complex+++GO:0045334///clathrin-coated endocytic vesicle GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0035091///phosphatidylinositol binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0003094///glomerular filtration+++GO:0006807///nitrogen compound metabolic process+++GO:0006897///endocytosis+++GO:0007015///actin filament organization+++GO:0030050///vesicle transport along actin filament+++GO:0030097///hemopoiesis+++GO:0032836///glomerular basement membrane development+++GO:0035166///post-embryonic hemopoiesis+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0072015///glomerular visceral epithelial cell development 71607 71607 'Snx20' mRNA 75 72 43 2.91 2.69 1.71 13.81 13.74 14.57 2.436666667 14.04 407 398 409 63.33333333 404.6666667 2.83E-44 2.670505068 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:1901981///phosphatidylinositol phosphate binding" GO:0015031///protein transport 71609 71609 'Tradd' mRNA 268 201 208 11.58 8.57 9.54 22.43 23.8 22.33 9.896666667 22.85333333 596 617 574 225.6666667 595.6666667 3.23E-23 1.389938781 04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04071///Sphingolipid signaling pathway+++04210///Apoptosis+++04217///Necroptosis+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04920///Adipocytokine signaling pathway+++04936///Alcoholic liver disease+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05152///Tuberculosis+++05160///Hepatitis C+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05203///Viral carcinogenesis GO:0002947///tumor necrosis factor receptor superfamily complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0043235///receptor complex+++GO:0045121///membrane raft GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0060090///molecular adaptor activity+++GO:0070513///death domain binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050729///positive regulation of inflammatory response+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051798///positive regulation of hair follicle development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling 71617 71617 'Armh3' mRNA 571 670 593 9.66 11.43 10.83 7.44 6.79 6.84 10.64 7.023333333 498 449 431 611.3333333 459.3333333 4.74E-04 -0.424324301 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:1903358///regulation of Golgi organization 71640 71640 'Zfp949' mRNA 1632 1791 1588 26.4 28.75 27.27 11.55 12.69 11.54 27.47333333 11.92666667 828 890 795 1670.333333 837.6666667 5.20E-32 -1.005678041 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 71643 71643 'Zgrf1' mRNA 46 48 53 0.47 0.5 0.53 0.61 0.6 0.57 0.5 0.593333333 76 82 79 49 79 0.037393884 0.675453101 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0008270///zinc ion binding+++GO:0017108///5'-flap endonuclease activity+++GO:0046872///metal ion binding GO:0071932///replication fork reversal 71648 71648 'Optn' mRNA 773.15 729.75 776.77 14.88 13.74 15.42 14.54 16.18 14.69 14.68 15.13666667 879.21 927.01 816.87 759.89 874.3633333 0.09720919 0.189917924 04137///Mitophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome "GO:0001155///TFIIIA-class transcription factor binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030674///protein binding, bridging+++GO:0031267///small GTPase binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding" GO:0001819///positive regulation of cytokine production+++GO:0001920///negative regulation of receptor recycling+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0016192///vesicle-mediated transport+++GO:0034067///protein localization to Golgi apparatus+++GO:0034613///cellular protein localization+++GO:0034620///cellular response to unfolded protein+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0090161///Golgi ribbon formation+++GO:1904417///positive regulation of xenophagy+++GO:2000179///positive regulation of neural precursor cell proliferation 71653 71653 'Shtn1' mRNA 2221 2250 1802 29.41 29.28 25.38 16.31 15.84 16.02 28.02333333 16.05666667 1421 1346 1350 2091 1372.333333 5.58E-15 -0.615520248 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0015630///microtubule cytoskeleton+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0044295///axonal growth cone+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0042802///identical protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0051015///actin filament binding "GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007265///Ras protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007409///axonogenesis+++GO:0032488///Cdc42 protein signal transduction+++GO:0038007///netrin-activated signaling pathway+++GO:0045773///positive regulation of axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051899///membrane depolarization+++GO:0060327///cytoplasmic actin-based contraction involved in cell motility+++GO:0061163///endoplasmic reticulum polarization+++GO:0061573///actin filament bundle retrograde transport+++GO:2000114///regulation of establishment of cell polarity+++GO:2001222///regulation of neuron migration+++GO:2001224///positive regulation of neuron migration" 71660 71660 'Rarres2' mRNA 1497.07 1506.08 1354.99 139.66 140.88 132.1 64.08 69.58 71.75 137.5466667 68.47 788.54 850.65 838.36 1452.713333 825.85 2.35E-22 -0.824752202 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0005515///protein binding GO:0001523///retinoid metabolic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0008286///insulin receptor signaling pathway+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0014823///response to activity+++GO:0019732///antifungal humoral response+++GO:0030154///cell differentiation+++GO:0031667///response to nutrient levels+++GO:0032869///cellular response to insulin stimulus+++GO:0045087///innate immune response+++GO:0045600///positive regulation of fat cell differentiation+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0048566///embryonic digestive tract development+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050873///brown fat cell differentiation+++GO:0050921///positive regulation of chemotaxis+++GO:0050994///regulation of lipid catabolic process+++GO:0061760///antifungal innate immune response+++GO:0061771///response to caloric restriction 71665 71665 'Fuca1' mRNA 4742.46 5082 4948 104.64 110.4 115.82 121.76 128.97 123.44 110.2866667 124.7233333 6347 6565 6230 4924.153333 6380.666667 1.50E-08 0.361625045 00511///Other glycan degradation+++04142///Lysosome GO:0005764///lysosome "GO:0004560///alpha-L-fucosidase activity+++GO:0015928///fucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding" GO:0005975///carbohydrate metabolic process+++GO:0006004///fucose metabolic process+++GO:0008152///metabolic process+++GO:0016139///glycoside catabolic process 71667 71667 'Tmem248' mRNA 1747 1738 723 26.04 25.25 11.67 11.67 13.94 14.04 20.98666667 13.21666667 887 1044 1060 1402.666667 997 0.280884601 -0.483509168 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 71670 71670 'Acy3' mRNA 303 332 292 15.48 16.53 15.78 8.41 9.13 8.65 15.93 8.73 186 196 186 309 189.3333333 6.93E-06 -0.716632518 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane "GO:0004046///aminoacylase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" 71673 71673 'Rnf215' mRNA 370 318 186 10.96 9.28 5.87 5.73 6.71 6.47 8.703333333 6.303333333 221 252 243 291.3333333 238.6666667 0.221578474 -0.286509833 GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017119///Golgi transport complex GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006623///protein targeting to vacuole+++GO:0006896///Golgi to vacuole transport+++GO:0016567///protein ubiquitination 71675 71675 '0610010F05Rik' mRNA 454.05 504.99 478.22 6.05 6.5 6.64 7.48 7.09 7.92 6.396666667 7.496666667 653 553.52 639.04 479.0866667 615.1866667 0.004491706 0.348414191 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71678 71678 'Brox' mRNA 1355.22 1484.39 1393.68 21.2 22.8 23.08 21.32 22.72 21.48 22.36 21.84 1566.89 1633.12 1533.08 1411.096667 1577.696667 0.092679083 0.149721228 GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 71679 71679 'Atp5h' mRNA 5045 5117 5055 685.36 692.75 728.74 656.05 760.56 668.11 702.2833333 694.9066667 5509 6198 5392 5072.333333 5699.666667 0.045213584 0.156808353 00190///Oxidative phosphorylation+++04714///Thermogenesis+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy "GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)" "GO:0015078///proton transmembrane transporter activity+++GO:0044877///protein-containing complex binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism" GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process+++GO:1901653///cellular response to peptide 71682 71682 'Wdr27' mRNA 134 184 168 2.11 3.05 3.18 0.19 0.25 0.41 2.78 0.283333333 13 17 27 162 19 1.07E-21 -3.103211012 GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 71683 71683 'Gypc' mRNA 1353 1438 1359 34.99 36.66 37.29 36.81 37.64 35.98 36.31333333 36.81 1636 1634 1549 1383.333333 1606.333333 0.012968391 0.203930529 05144///Malaria GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030863///cortical cytoskeleton 71684 71684 'Rbm43' mRNA 365 372 391 10.04 10.03 11.33 15.52 14.89 16.49 10.46666667 15.63333333 645 617 656 376 639.3333333 2.22E-10 0.752262326 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0008150///biological_process 71685 71685 'Galnt14' mRNA 25 6 29 0.51 0.13 0.7 0.22 0.3 0.12 0.446666667 0.213333333 13 15 6 20 11.33333333 0.308797666 -0.850181029 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008150///biological_process 71687 71687 'Tmem25' mRNA 378 437 436 8.15 9.23 10.01 5.66 5.42 5.2 9.13 5.426666667 295 280 258 417 277.6666667 4.42E-05 -0.600796282 GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0031647///regulation of protein stability+++GO:0090394///negative regulation of excitatory postsynaptic potential 71690 71690 'Esm1' mRNA 0 0 1 0 0 0.03 1.38 1.1 1.67 0.01 1.383333333 59 46 69 0.333333333 58 1.66E-08 7.325919713 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0005171///hepatocyte growth factor receptor binding+++GO:0005178///integrin binding+++GO:0005520///insulin-like growth factor binding GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:1902204///positive regulation of hepatocyte growth factor receptor signaling pathway 71691 71691 'Pnmal1' mRNA 37 41 26 0.49 0.49 0.34 0.39 0.25 0.35 0.44 0.33 34 21 31 34.66666667 28.66666667 0.620352527 -0.28144618 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71693 71693 'Colec11' mRNA 47 48 41 1.96 2.35 2.58 0.4 0.71 0.89 2.296666667 0.666666667 11 15 20 45.33333333 15.33333333 9.24E-04 -1.570785206 04145///Phagosome GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space GO:0003677///DNA binding+++GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding+++GO:0042806///fucose binding+++GO:0046872///metal ion binding+++GO:0070492///oligosaccharide binding+++GO:0120153///calcium-dependent carbohydrate binding "GO:0001867///complement activation, lectin pathway+++GO:0002376///immune system process+++GO:0006956///complement activation+++GO:0007275///multicellular organism development+++GO:0019730///antimicrobial humoral response+++GO:0032502///developmental process+++GO:0045087///innate immune response" 71699 71699 'Slc41a3' mRNA 942 999 906 23.79 24.84 24.26 16.14 16.8 15.48 24.29666667 16.14 739 751 685 949 725 3.54E-05 -0.399126713 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0008324///cation transmembrane transporter activity GO:0006812///cation transport+++GO:0098655///cation transmembrane transport 71701 71701 'Pnpt1' mRNA 488 440 482 9.91 8.76 10.56 13.83 12.55 12.78 9.743333333 13.05333333 772 687 699 470 719.3333333 1.83E-07 0.599608565 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042788///polysomal ribosome+++GO:0045025///mitochondrial degradosome GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004654///polyribonucleotide nucleotidyltransferase activity+++GO:0008266///poly(U) RNA binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0034046///poly(G) binding+++GO:0035198///miRNA binding "GO:0000957///mitochondrial RNA catabolic process+++GO:0000958///mitochondrial mRNA catabolic process+++GO:0000962///positive regulation of mitochondrial RNA catabolic process+++GO:0000964///mitochondrial RNA 5'-end processing+++GO:0000965///mitochondrial RNA 3'-end processing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0006401///RNA catabolic process+++GO:0006402///mRNA catabolic process+++GO:0034599///cellular response to oxidative stress+++GO:0035458///cellular response to interferon-beta+++GO:0035927///RNA import into mitochondrion+++GO:0035928///rRNA import into mitochondrion+++GO:0043457///regulation of cellular respiration+++GO:0043631///RNA polyadenylation+++GO:0045926///negative regulation of growth+++GO:0051260///protein homooligomerization+++GO:0051591///response to cAMP+++GO:0051726///regulation of cell cycle+++GO:0060416///response to growth hormone+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0070207///protein homotrimerization+++GO:0070584///mitochondrion morphogenesis+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process+++GO:0071850///mitotic cell cycle arrest+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0097222///mitochondrial mRNA polyadenylation+++GO:0097421///liver regeneration+++GO:2000627///positive regulation of miRNA catabolic process+++GO:2000772///regulation of cellular senescence" 71702 71702 'Cdc5l' mRNA 1722.96 1807.74 1751 31.61 32.64 34.08 36.12 34.45 37.34 32.77666667 35.97 2264.93 2109.85 2267 1760.566667 2213.926667 1.48E-05 0.318054064 03040///Spliceosome GO:0000974///Prp19 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001222///transcription corepressor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019901///protein kinase binding+++GO:0043522///leucine zipper domain binding+++GO:0071987///WD40-repeat domain binding" "GO:0000077///DNA damage checkpoint+++GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006281///DNA repair+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:1904568///cellular response to wortmannin+++GO:1990090///cellular response to nerve growth factor stimulus" 71703 71703 'Armcx3' mRNA 1825 1992 1946 28.48 30.69 32.4 32.4 30.37 32.45 30.52333333 31.74 2387 2176 2306 1921 2289.666667 0.0021627 0.239860632 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0007005///mitochondrion organization+++GO:0019896///axonal transport of mitochondrion+++GO:0034613///cellular protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II 71704 71704 'Arhgef3' mRNA 642 625 659 9.47 9.08 10.37 15.45 15.06 15.22 9.64 15.24333333 1208 1147 1150 642 1168.333333 1.05E-19 0.850232253 GO:0005737///cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 71706 71706 'Slc46a3' mRNA 592 579 576 12.41 12.27 12.82 10.07 10.72 10.54 12.5 10.44333333 537 547 536 582.3333333 540 0.354187095 -0.12075994 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1905103///integral component of lysosomal membrane GO:0022857///transmembrane transporter activity GO:0034486///vacuolar transmembrane transport+++GO:0055085///transmembrane transport 71707 71707 'Ubiad1' mRNA 631 701 567 11.63 12.72 11.09 12.63 11.66 10.42 11.81333333 11.57 788 711 630 633 709.6666667 0.232386243 0.155134178 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane "GO:0004659///prenyltransferase activity+++GO:0016209///antioxidant activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups" "GO:0001885///endothelial cell development+++GO:0006744///ubiquinone biosynthetic process+++GO:0009234///menaquinone biosynthetic process+++GO:0032194///ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate+++GO:0042371///vitamin K biosynthetic process+++GO:0072359///circulatory system development+++GO:0098869///cellular oxidant detoxification" 71709 71709 'Syde1' mRNA 430 430 346 7.14 7.02 6.17 6.02 6.69 5.89 6.776666667 6.2 417 453 395 402 421.6666667 0.738955171 0.061620226 GO:0005829///cytosol+++GO:0044300///cerebellar mossy fiber+++GO:0097060///synaptic membrane+++GO:0098793///presynapse GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity+++GO:0044877///protein-containing complex binding GO:0007130///synaptonemal complex assembly+++GO:0007165///signal transduction+++GO:0016081///synaptic vesicle docking+++GO:0016477///cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0043547///positive regulation of GTPase activity+++GO:0046578///regulation of Ras protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0050806///positive regulation of synaptic transmission+++GO:0051493///regulation of cytoskeleton organization+++GO:0060711///labyrinthine layer development+++GO:0060716///labyrinthine layer blood vessel development+++GO:0090630///activation of GTPase activity+++GO:1901165///positive regulation of trophoblast cell migration 71710 71710 'Lrrcc1' mRNA 480 456 460 5.48 5.28 5.74 4.87 5.09 4.61 5.5 4.856666667 419 434 401 465.3333333 418 0.238473453 -0.166664161 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0051301///cell division 71711 71711 'Mus81' mRNA 615 668 580 14.9 15.94 14.91 13.34 13.72 13.67 15.25 13.57666667 633 636 628 621 632.3333333 0.906552713 0.016183558 03440///Homologous recombination+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0048476///Holliday junction resolvase complex GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0048257///3'-flap endonuclease activity "GO:0000712///resolution of meiotic recombination intermediates+++GO:0000727///double-strand break repair via break-induced replication+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031573///intra-S DNA damage checkpoint+++GO:0033687///osteoblast proliferation+++GO:0072429///response to intra-S DNA damage checkpoint signaling" 71712 71712 'Dram1' mRNA 25 21 32 0.49 0.41 0.67 4.89 5.09 5.58 0.523333333 5.186666667 286 291 316 26 297.6666667 5.86E-46 3.502647797 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0010506///regulation of autophagy 71713 71713 'Cdc40' mRNA 885 911 914 14.33 14.52 15.7 10.96 10.96 12.66 14.85 11.52666667 779 761 871 903.3333333 803.6666667 0.103199541 -0.181287908 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003729///mRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 71715 71715 'Dhx35' mRNA 281 286 287 4.79 4.7 5.05 4.5 3.67 3.93 4.846666667 4.033333333 312 249 260 284.6666667 273.6666667 0.740213982 -0.071300273 GO:0005622///intracellular+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0001701///in utero embryonic development 71718 71718 'Telo2' mRNA 447 495 521 7.01 7.62 8.68 5.63 5.62 5.69 7.77 5.646666667 411 402 401 487.6666667 404.6666667 0.042623636 -0.28370084 03460///Fanconi anemia pathway+++04150///mTOR signaling pathway "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031931///TORC1 complex+++GO:0031932///TORC2 complex+++GO:0034399///nuclear periphery+++GO:0070209///ASTRA complex" GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042162///telomeric DNA binding+++GO:0044877///protein-containing complex binding+++GO:0051879///Hsp90 protein binding+++GO:0060090///molecular adaptor activity GO:0007004///telomere maintenance via telomerase+++GO:0032006///regulation of TOR signaling+++GO:0050821///protein stabilization+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1904263///positive regulation of TORC1 signaling+++GO:1904515///positive regulation of TORC2 signaling 71720 71720 'Osbpl3' mRNA 1326 1440 1377 9.98 10.61 11.17 3.55 3.5 3.27 10.58666667 3.44 534 510 471 1381 505 1.69E-54 -1.464040552 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0032433///filopodium tip+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097038///perinuclear endoplasmic reticulum GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0015918///sterol transport 71721 71721 'Fam13c' mRNA 717.13 718.5 631.65 11.68 11.48 11.03 8.03 7.09 7.62 11.39666667 7.58 566.8 495.52 520.76 689.0933333 527.6933333 2.85E-04 -0.396666989 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71722 71722 'Cic' mRNA 1722 1696 1432 11.15 10.86 9.85 13.75 12.14 13.14 10.62 13.01 2137 1843 1987 1616.666667 1989 3.30E-04 0.289230552 04013///MAPK signaling pathway - fly+++05017///Spinocerebellar ataxia GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007612///learning+++GO:0007613///memory+++GO:0035176///social behavior+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048286///lung alveolus development" 71723 71723 'Dhx34' mRNA 544 555 587 8.48 8.63 9.15 7.9 6.8 5.91 8.753333333 6.87 494 463 405 562 454 0.015333116 -0.322580622 GO:0005622///intracellular GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:2000623///negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 71724 71724 'Aox3' mRNA 15 26 29 0.16 0.26 0.35 0.27 0.27 0.37 0.256666667 0.303333333 30 26 36 23.33333333 30.66666667 0.53557491 0.375607389 "00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00380///Tryptophan metabolism+++00750///Vitamin B6 metabolism+++00760///Nicotinate and nicotinamide metabolism+++00830///Retinol metabolism+++00982///Drug metabolism - cytochrome P450+++04630///JAK-STAT signaling pathway" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004031///aldehyde oxidase activity+++GO:0005506///iron ion binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0030151///molybdenum ion binding+++GO:0042803///protein homodimerization activity+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050250///retinal oxidase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0071949///FAD binding+++GO:0102797///geranial:oxygen oxidoreductase activity+++GO:0102798///heptaldehyde:oxygen oxidoreductase activity" GO:0017144///drug metabolic process+++GO:0022900///electron transport chain 71726 71726 'Smug1' mRNA 410 444 401 6.07 6.46 6.33 4.6 4.39 4.09 6.286666667 4.36 354 332 305 418.3333333 330.3333333 0.011362662 -0.352195308 03410///Base excision repair GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0000702///oxidized base lesion DNA N-glycosylase activity+++GO:0000703///oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004844///uracil DNA N-glycosylase activity+++GO:0016787///hydrolase activity+++GO:0017065///single-strand selective uracil DNA N-glycosylase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0042802///identical protein binding GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus 71728 71728 'Stk11ip' mRNA 1154 1210 1119 15.34 15.91 15.79 9.45 8.36 8.35 15.68 8.72 820 719 701 1161 746.6666667 1.51E-12 -0.649111121 GO:0005737///cytoplasm GO:0019901///protein kinase binding GO:0008104///protein localization 71729 71729 'Rgs12' mRNA 1311 1497 1321 15.82 17.08 17.27 3.87 4.41 4.52 16.72333333 4.266666667 430 442 494 1376.333333 455.3333333 8.60E-59 -1.606070795 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0097440///apical dendrite GO:0001965///G-protein alpha-subunit binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030695///GTPase regulator activity GO:0007165///signal transduction+++GO:0038032///termination of G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 71732 71732 'Vps11' mRNA 1699 1819 1726 26.15 27.52 28.17 21.94 22.71 20.96 27.28 21.87 1641 1659 1516 1748 1605.333333 0.120551868 -0.134683874 05132///Salmonella infection GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030139///endocytic vesicle+++GO:0030897///HOPS complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0033263///CORVET complex+++GO:0048786///presynaptic active zone "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0019905///syntaxin binding+++GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" GO:0006886///intracellular protein transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006914///autophagy+++GO:0007032///endosome organization+++GO:0007033///vacuole organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016567///protein ubiquitination+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0034058///endosomal vesicle fusion+++GO:0035542///regulation of SNARE complex assembly+++GO:0048284///organelle fusion+++GO:1901998///toxin transport+++GO:1902115///regulation of organelle assembly+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:2000643///positive regulation of early endosome to late endosome transport 71733 71733 'Susd2' mRNA 103 134 122 1.73 2.21 2.26 1.26 1.39 0.9 2.066666667 1.183333333 84 91 59 119.6666667 78 0.026155935 -0.629735232 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0051782///negative regulation of cell division+++GO:1902807///negative regulation of cell cycle G1/S phase transition 71735 71735 'Lrwd1' mRNA 401 363 397 10.38 9.26 10.91 10.09 8.56 9.86 10.18333333 9.503333333 448 371 424 387 414.3333333 0.638173993 0.083610366 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle" GO:0003682///chromatin binding+++GO:0008327///methyl-CpG binding+++GO:0035064///methylated histone binding GO:0006260///DNA replication+++GO:0006325///chromatin organization+++GO:0071169///establishment of protein localization to chromatin 71738 71738 'Mamdc2' mRNA 44 59 25 0.72 0.95 0.43 1.13 1.15 1.2 0.7 1.16 80 79 82 42.66666667 80.33333333 0.01085902 0.913784311 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0031012///extracellular matrix GO:0005539///glycosaminoglycan binding GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 71740 71740 'Nectin4' mRNA 788 852 782 12.29 13.08 12.98 10.1 8.17 8.77 12.78333333 9.013333333 743 586 626 807.3333333 651.6666667 0.004330359 -0.322220897 04520///Adherens junction GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0046718///viral entry into host cell+++GO:0098609///cell-cell adhesion 71742 71742 'Ulk3' mRNA 536.25 538.78 587.86 10.47 10.45 12.55 7.1 5.87 7.3 11.15666667 6.756666667 409.35 329.92 405 554.2966667 381.4233333 4.53E-05 -0.555208909 GO:0005737///cytoplasm+++GO:0005776///autophagosome GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006914///autophagy+++GO:0007224///smoothened signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0072537///fibroblast activation+++GO:1905037///autophagosome organization 71743 71743 'Coasy' mRNA 1057 1184 1148 28.69 30.84 33.18 28.13 26.1 29.75 30.90333333 27.99333333 1198 1108 1210 1129.666667 1172 0.749855753 0.039919687 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004044///amidophosphoribosyltransferase activity+++GO:0004140///dephospho-CoA kinase activity+++GO:0004595///pantetheine-phosphate adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016779///nucleotidyltransferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding" GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001822///kidney development+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006543///glutamine catabolic process+++GO:0007595///lactation+++GO:0008152///metabolic process+++GO:0009058///biosynthetic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation+++GO:0019693///ribose phosphate metabolic process+++GO:0031100///animal organ regeneration+++GO:0032869///cellular response to insulin stimulus+++GO:0035690///cellular response to drug+++GO:0042493///response to drug+++GO:0060135///maternal process involved in female pregnancy 71745 71745 'Cul2' mRNA 634 821 702 10.01 12.86 11.86 12.35 13.4 13.06 11.57666667 12.93666667 870 923 905 719 899.3333333 0.007208183 0.312633996 04066///HIF-1 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05200///Pathways in cancer+++05211///Renal cell carcinoma GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031462///Cul2-RING ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 71746 71746 'Rgl3' mRNA 361 334 273 7.64 6.9 6.22 5.93 4.6 5.25 6.92 5.26 317 243 273 322.6666667 277.6666667 0.203821703 -0.22637103 GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity 71750 71750 'R3hdm2' mRNA 816 742 694 12.5 11.58 11.9 9.99 9.59 9.66 11.99333333 9.746666667 732 659 710 750.6666667 700.3333333 0.356690886 -0.111060894 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003676///nucleic acid binding GO:0008150///biological_process 71751 71751 'Map3k13' mRNA 459.02 456.56 369.03 2.08 1.99 1.82 0.54 0.48 0.39 1.963333333 0.47 156.91 129.78 106.04 428.2033333 130.91 1.10E-24 -1.724939077 04010///MAPK signaling pathway+++04361///Axon regeneration GO:0005737///cytoplasm+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0106137///IkappaB kinase complex binding GO:0000186///activation of MAPKK activity+++GO:0006468///protein phosphorylation+++GO:0007254///JNK cascade+++GO:0007256///activation of JNKK activity+++GO:0007257///activation of JUN kinase activity+++GO:0014042///positive regulation of neuron maturation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045773///positive regulation of axon extension+++GO:0045860///positive regulation of protein kinase activity+++GO:0046777///protein autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051403///stress-activated MAPK cascade+++GO:0150012///positive regulation of neuron projection arborization+++GO:1905492///positive regulation of branching morphogenesis of a nerve 71752 71752 'Gtf3c2' mRNA 2147 2214 2275 25.31 25.66 28.44 19.95 19.99 21.35 26.47 20.43 1948 1907 2020 2212 1958.333333 0.020981761 -0.189218903 GO:0000127///transcription factor TFIIIC complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003677///DNA binding GO:0006383///transcription by RNA polymerase III 71753 71753 'Tmprss6' mRNA 1967 2033 1958 33.82 34.37 35.7 12.97 11.5 11.23 34.63 11.9 870 753 729 1986 784 9.46E-59 -1.354222881 GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006879///cellular iron ion homeostasis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0033619///membrane protein proteolysis+++GO:0042730///fibrinolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0055072///iron ion homeostasis+++GO:0097264///self proteolysis" 71755 71755 'Dhdh' mRNA 480.09 450.11 577.17 7.86 7.44 9.68 9.48 6.96 9.33 8.326666667 8.59 694.38 490.76 663.19 502.4566667 616.11 0.105200629 0.272800556 00040///Pentose and glucuronate interconversions+++00980///Metabolism of xenobiotics by cytochrome P450 "GO:0000166///nucleotide binding+++GO:0016491///oxidoreductase activity+++GO:0047115///trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity+++GO:0047837///D-xylose 1-dehydrogenase (NADP+) activity" GO:0042843///D-xylose catabolic process 71760 71760 'Etnppl' mRNA 1842 1838 1745 37.91 37.23 38.09 11.57 12.18 12.18 37.74333333 11.97666667 647 665 659 1808.333333 657 2.17E-74 -1.471764488 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0050459///ethanolamine-phosphate phospho-lyase activity GO:0008150///biological_process 71761 71761 'Amdhd1' mRNA 2 0 3 0.05 0 0.07 0.29 0.47 0.78 0.04 0.513333333 11 16 25 1.666666667 17.33333333 0.001376601 3.357384923 00340///Histidine metabolism GO:0005737///cytoplasm "GO:0016787///hydrolase activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0016812///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides+++GO:0046872///metal ion binding+++GO:0050480///imidazolonepropionase activity" GO:0006547///histidine metabolic process+++GO:0006548///histidine catabolic process+++GO:0019556///histidine catabolic process to glutamate and formamide+++GO:0019557///histidine catabolic process to glutamate and formate 71764 71764 'C2cd2l' mRNA 682 622 408 8.46 7.59 5.37 5.12 5.22 5.05 7.14 5.13 475 473 454 570.6666667 467.3333333 0.07502409 -0.290826649 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032541///cortical endoplasmic reticulum+++GO:0098592///cytoplasmic side of apical plasma membrane GO:0008289///lipid binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0035091///phosphatidylinositol binding+++GO:0043559///insulin binding GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0120009///intermembrane lipid transfer 71765 71765 'Klhdc3' mRNA 2030 1995 1868 54.16 52.47 52.77 39.88 40.65 40.19 53.13333333 40.24 1712.97 1704.97 1673 1964.333333 1696.98 0.002167063 -0.222464309 GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003682///chromatin binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051321///meiotic cell cycle 71766 71766 'Raver1' mRNA 1623 1567 1468 25.52 24.24 24.48 20.88 20.49 20.49 24.74666667 20.62 1528 1465 1452 1552.666667 1481.666667 0.376062772 -0.078571122 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome" 71767 71767 'Tysnd1' mRNA 837 782 741 20.62 18.93 19.34 18.45 18.92 19.83 19.63 19.06666667 862 862 896 786.6666667 873.3333333 0.190851339 0.140252527 GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix GO:0002020///protease binding+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0031998///regulation of fatty acid beta-oxidation 71768 71768 'Vwce' mRNA 0 2 1 0 0.05 0.02 0.08 0.07 0.04 0.023333333 0.063333333 6 3 3 1 4 0.297830499 1.985151995 GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0005509///calcium ion binding GO:0098586///cellular response to virus 71769 71769 'Bbs10' mRNA 169 188 199 3.39 3.72 4.24 1.71 1.79 2.22 3.783333333 1.906666667 98 100 123 185.3333333 107 2.51E-04 -0.806490353 GO:0005575///cellular_component+++GO:0005929///cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0043254///regulation of protein complex assembly+++GO:0045494///photoreceptor cell maintenance+++GO:0051131///chaperone-mediated protein complex assembly+++GO:1905515///non-motile cilium assembly 71770 71770 'Ap2b1' mRNA 2568.19 2716 1756 28.05 29.34 20.26 23.31 22.2 22.75 25.88333333 22.75333333 2438 2234 2283 2346.73 2318.333333 0.878389955 -0.021044996 04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030118///clathrin coat+++GO:0030122///AP-2 adaptor complex+++GO:0030131///clathrin adaptor complex+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0030276///clathrin binding+++GO:0044877///protein-containing complex binding GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0003281///ventricular septum development+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007507///heart development+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0035904///aorta development+++GO:0045807///positive regulation of endocytosis+++GO:0048268///clathrin coat assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0060976///coronary vasculature development+++GO:0072583///clathrin-dependent endocytosis+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:0099590///neurotransmitter receptor internalization+++GO:1901215///negative regulation of neuron death+++GO:1905477///positive regulation of protein localization to membrane 71772 71772 'Plbd2' mRNA 4335 4451 4132 65.47 66.13 66.19 75.21 78.65 76.11 65.93 76.65666667 5732 5855 5617 4306 5734.666667 7.71E-13 0.402581868 GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen GO:0004620///phospholipase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0009395///phospholipid catabolic process+++GO:0016042///lipid catabolic process 71774 71774 'Shroom1' mRNA 323 421 340 5.39 7.14 6.31 4.38 4.09 4.09 6.28 4.186666667 292 268 271 361.3333333 277 0.012739004 -0.393784758 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005912///adherens junction+++GO:0016324///apical plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0043296///apical junction complex GO:0003779///actin binding+++GO:0045159///myosin II binding+++GO:0051015///actin filament binding GO:0000902///cell morphogenesis+++GO:0007015///actin filament organization+++GO:0051017///actin filament bundle assembly 71775 71775 '1300017J02Rik' mRNA 0 6 2 0 0.18 0.07 0.03 0.06 0.21 0.083333333 0.1 1 2 7 2.666666667 3.333333333 0.868716894 0.329586916 04066///HIF-1 signaling pathway+++04216///Ferroptosis+++04978///Mineral absorption GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0055037///recycling endosome GO:0004857///enzyme inhibitor activity+++GO:0005506///iron ion binding GO:0006826///iron ion transport+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity 71776 71776 'Tha1' mRNA 275 262 265 9.1 8.47 9.28 12.17 10.62 10.77 8.95 11.18666667 430 366 372 267.3333333 389.3333333 2.73E-04 0.528869394 "00260///Glycine, serine and threonine metabolism+++01230///Biosynthesis of amino acids" GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0008732///L-allo-threonine aldolase activity+++GO:0016829///lyase activity GO:0006520///cellular amino acid metabolic process+++GO:0006545///glycine biosynthetic process+++GO:0006567///threonine catabolic process 71777 71777 'Ing3' mRNA 812 816 683 11.55 11.52 10.3 6.25 6.72 7.04 11.12333333 6.67 501 526 547 770.3333333 524.6666667 2.16E-07 -0.562124771 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0035267///NuA4 histone acetyltransferase complex GO:0035064///methylated histone binding+++GO:0046872///metal ion binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0040008///regulation of growth+++GO:0043065///positive regulation of apoptotic process+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation" 71778 71778 'Klhl5' mRNA 541 565 482 9.06 9.28 8.48 6.91 5.8 6.63 8.94 6.446666667 468 388 442 529.3333333 432.6666667 0.018349839 -0.301575344 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71779 71779 'Marchf8' mRNA 1661 1745 1121 18.14 18.5 12.47 9.38 12.14 11.54 16.37 11.02 997 1202 1141 1509 1113.333333 6.37E-04 -0.439402624 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042287///MHC protein binding+++GO:0042289///MHC class II protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002495///antigen processing and presentation of peptide antigen via MHC class II+++GO:0006955///immune response+++GO:0016567///protein ubiquitination+++GO:0045347///negative regulation of MHC class II biosynthetic process 71780 71780 'Isyna1' mRNA 4232 4252 4137 132.37 131.06 137.27 330.49 312.91 331.83 133.5666667 325.0766667 12145 11224 11801 4207 11723.33333 5.47E-173 1.465960152 00562///Inositol phosphate metabolism GO:0005737///cytoplasm GO:0004512///inositol-3-phosphate synthase activity+++GO:0016853///isomerase activity GO:0006021///inositol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process 71781 71781 'Slc16a14' mRNA 99.32 70.88 73.77 0.9 0.63 0.71 1.13 1.24 1 0.746666667 1.123333333 143.79 154.11 123.11 81.32333333 140.3366667 0.00222954 0.785398154 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport 71782 71782 'Ankle2' mRNA 1396.13 1415 761.05 14.16 14.11 8.18 8.32 11.34 10.72 12.15 10.12666667 945.05 1258 1179 1190.726667 1127.35 0.863090843 -0.073844657 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0051721///protein phosphatase 2A binding GO:0007049///cell cycle+++GO:0007084///mitotic nuclear envelope reassembly+++GO:0007417///central nervous system development+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0042326///negative regulation of phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0051301///cell division 71785 71785 'Pdgfd' mRNA 850 949 936 14.69 16.11 17.13 8.21 7.17 7.23 15.97666667 7.536666667 546 468 467 911.6666667 493.6666667 2.66E-16 -0.899433505 01521///EGFR tyrosine kinase inhibitor resistance+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04540///Gap junction+++04810///Regulation of actin cytoskeleton+++05215///Prostate cancer+++05218///Melanoma+++05231///Choline metabolism in cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane GO:0005161///platelet-derived growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0070851///growth factor receptor binding GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0009987///cellular process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030335///positive regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0043406///positive regulation of MAP kinase activity+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0051781///positive regulation of cell division+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071230///cellular response to amino acid stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0071673///positive regulation of smooth muscle cell chemotaxis+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:2000439///positive regulation of monocyte extravasation 71787 71787 'Trnau1ap' mRNA 917 929 888 48.87 49.06 50.15 43.72 42.82 41.16 49.36 42.56666667 932 893 857 911.3333333 894 0.75009672 -0.039615583 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000049///tRNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding GO:0001514///selenocysteine incorporation+++GO:0006412///translation 71790 71790 'Anxa9' mRNA 572.45 576.18 520.85 10.65 11.21 10.71 8.06 8.32 9.26 10.85666667 8.546666667 548.69 523.11 567.89 556.4933333 546.5633333 0.815602368 -0.036624769 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0031982///vesicle+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix "GO:0001786///phosphatidylserine binding+++GO:0002020///protease binding+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0015464///acetylcholine receptor activity+++GO:0019834///phospholipase A2 inhibitor activity+++GO:0046790///virion binding" "GO:0007271///synaptic transmission, cholinergic+++GO:0043086///negative regulation of catalytic activity+++GO:0070588///calcium ion transmembrane transport+++GO:0098609///cell-cell adhesion" 71791 71791 'Cpa4' mRNA 2 1 5 0.04 0.02 0.11 0.53 0.25 0.51 0.056666667 0.43 30 14 28 2.666666667 24 2.52E-04 3.138126294 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 71793 71793 'Ints12' mRNA 499 519 533 8.86 9.07 10.04 9.25 9.53 9.07 9.323333333 9.283333333 599 603 569 517 590.3333333 0.166179294 0.178170916 GO:0005634///nucleus+++GO:0032039///integrator complex GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing 71795 71795 'Pitpnc1' mRNA 3297 3300 3374 27.54 27.12 29.95 22 20.46 22.34 28.20333333 21.6 3031 2757 2981 3323.666667 2923 0.005807134 -0.19918567 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005548///phospholipid transporter activity+++GO:0008289///lipid binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0035091///phosphatidylinositol binding+++GO:0070300///phosphatidic acid binding+++GO:1901611///phosphatidylglycerol binding+++GO:1990050///phosphatidic acid transporter activity GO:0006869///lipid transport+++GO:0007165///signal transduction+++GO:0015914///phospholipid transport+++GO:0046488///phosphatidylinositol metabolic process+++GO:0120009///intermembrane lipid transfer 71797 71797 'Chst13' mRNA 0 2 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001537///N-acetylgalactosamine 4-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0047756///chondroitin 4-sulfotransferase activity GO:0005975///carbohydrate metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process 71799 71799 'Ptcd1' mRNA 600.97 604.97 637.88 10.79 10.59 11.98 8.94 8.46 8.5 11.12 8.633333333 579.49 546.52 537.31 614.6066667 554.44 0.206262742 -0.161696365 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding GO:0008033///tRNA processing+++GO:0032543///mitochondrial translation+++GO:0042780///tRNA 3'-end processing 71801 71801 'Plekhf2' mRNA 1122 1164 554 21.15 21.59 11.08 8.21 11.98 12.82 17.94 11.00333333 501 714 758 946.6666667 657.6666667 0.214208915 -0.517289431 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0030133///transport vesicle+++GO:0031901///early endosome membrane GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding GO:0015031///protein transport 71803 71803 'Slc25a18' mRNA 187 178 200 4.84 4.81 5.76 2.27 0.92 1.34 5.136666667 1.51 93 52 62 188.3333333 69 3.25E-09 -1.46784446 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005313///L-glutamate transmembrane transporter activity+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0015810///aspartate transmembrane transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0055085///transmembrane transport+++GO:0070778///L-aspartate transmembrane transport 71804 71804 'Mtfr2' mRNA 3 7 6 0.07 0.17 0.15 0.47 0.37 0.57 0.13 0.47 22 17 28 5.333333333 22.33333333 0.005445906 2.052069907 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0000266///mitochondrial fission+++GO:0007005///mitochondrion organization+++GO:0009060///aerobic respiration 71805 71805 'Nup93' mRNA 683.07 711.18 742.81 11.83 11.93 13.84 16.93 16.45 17.69 12.53333333 17.02333333 1102.82 1026.3 1097.76 712.3533333 1075.626667 3.01E-09 0.580337081 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery GO:0005515///protein binding+++GO:0017056///structural constituent of nuclear pore GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006998///nuclear envelope organization+++GO:0015031///protein transport+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0060395///SMAD protein signal transduction 71807 71807 'Tars2' mRNA 751 753 817 16.76 16.71 19.44 15.94 15.53 16.04 17.63666667 15.83666667 815 768 793 773.6666667 792 0.888356807 0.019077431 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004829///threonine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0042803///protein homodimerization activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006435///threonyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0106074///aminoacyl-tRNA metabolism involved in translational fidelity 71810 71810 'Ranbp3' mRNA 1316 1415 1409 28.74 30.4 32.64 30.86 29.91 31.96 30.59333333 30.91 1621 1542 1620 1380 1594.333333 0.025547769 0.195023137 05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding+++GO:0070412///R-SMAD binding GO:0006611///protein export from nucleus+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0046907///intracellular transport+++GO:0050790///regulation of catalytic activity 71816 71816 'Rnf180' mRNA 714 743 801 14.56 14.56 17.15 5.72 5.96 5.63 15.42333333 5.77 307 315 314 752.6666667 312 5.74E-26 -1.284877547 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031227///intrinsic component of endoplasmic reticulum membrane GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0030534///adult behavior+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0042415///norepinephrine metabolic process+++GO:0042428///serotonin metabolic process+++GO:0050790///regulation of catalytic activity+++GO:1901360///organic cyclic compound metabolic process 71817 71817 'Tmem50a' mRNA 3938.66 4215.5 3902.78 219.29 231.23 229.8 267.08 282.54 272.81 226.7733333 274.1433333 5529.72 5683.81 5430.27 4018.98 5547.933333 1.94E-14 0.454190145 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0097386///glial cell projection GO:0003674///molecular_function GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway 71819 71819 'Kif23' mRNA 9 6 20 0.16 0.09 0.34 4.36 4.6 4.56 0.196666667 4.506666667 302 309 304 11.66666667 305 3.63E-50 4.690786709 05206///MicroRNAs in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle+++GO:0090543///Flemming body+++GO:0097149///centralspindlin complex GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0000281///mitotic cytokinesis+++GO:0007018///microtubule-based movement+++GO:0007049///cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0051256///mitotic spindle midzone assembly+++GO:0051301///cell division 71820 71820 'Wdr34' mRNA 1646.18 1716.17 1754.17 52.48 53.92 59.33 17.32 17.68 16.96 55.24333333 17.32 624.29 622.32 591.83 1705.506667 612.8133333 2.88E-62 -1.491229635 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030175///filopodium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097014///ciliary plasm GO:0005515///protein binding+++GO:0045503///dynein light chain binding+++GO:0045504///dynein heavy chain binding GO:0007018///microtubule-based movement+++GO:0035721///intraciliary retrograde transport+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly 71826 71826 '1700001F09Rik' mRNA 3 0 2.47 0.22 0 0.2 0 0 0 0.14 0 0 0 0 1.823333333 0 0.36918796 -3.205220859 GO:0003674///molecular_function GO:0008150///biological_process 71827 71827 'Lrrc34' mRNA 144 173 165 4.5 5.33 5.47 0.95 0.5 0.7 5.1 0.716666667 35 18 25 160.6666667 26 3.97E-19 -2.643861202 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0030154///cell differentiation 71828 71828 'Gtf2a1l' mRNA 0 4 1 0 0.14 0.04 0 0 0.06 0.06 0.02 0 0 2 1.666666667 0.666666667 0.704909614 -1.30798949 03022///Basal transcription factors+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005672///transcription factor TFIIA complex+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0050890///cognition 71829 71829 'Ddi1' mRNA 3 5 1 0.12 0.19 0.04 0.07 0.07 0.03 0.116666667 0.056666667 2 2 1 3 1.666666667 0.688777957 -0.838307992 GO:0005575///cellular_component GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0072711///cellular response to hydroxyurea+++GO:0097752///regulation of DNA stability 71832 71832 'Csl' mRNA 2 0 2 0.06 0 0.06 0 0 0 0.04 0 0 0 0 1.333333333 0 0.468848267 -2.893033412 00020///Citrate cycle (TCA cycle)+++00630///Glyoxylate and dicarboxylate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0004108///citrate (Si)-synthase activity GO:0005975///carbohydrate metabolic process+++GO:0006084///acetyl-CoA metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006101///citrate metabolic process+++GO:0006107///oxaloacetate metabolic process 71833 71833 'Dcaf7' mRNA 2811 3071 2996 25.98 27.9 29.37 22.96 21.62 21.87 27.75 22.15 2861 2632 2639 2959.333333 2710.666667 0.070621882 -0.140157527 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination 71834 71834 'Zbtb43' mRNA 501 563 522 5.32 5.89 5.88 5.15 5 4.84 5.696666667 4.996666667 556 528 509 528.6666667 531 0.975404691 -0.005732703 GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 71835 71835 'Lancl2' mRNA 755 876 769 11.2 12.78 12.1 6.82 7.22 7.45 12.02666667 7.163333333 529 547 560 800 545.3333333 1.63E-07 -0.563147455 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0070273///phosphatidylinositol-4-phosphate binding "GO:0005975///carbohydrate metabolic process+++GO:0009789///positive regulation of abscisic acid-activated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated" 71836 71836 'Shcbp1l' mRNA 102 94 98 2.83 2.57 2.92 0.31 0.59 0.47 2.773333333 0.456666667 13 24 19 98 18.66666667 1.94E-11 -2.40201726 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0072687///meiotic spindle GO:0005515///protein binding GO:0007112///male meiosis cytokinesis+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:2001252///positive regulation of chromosome organization 71837 71837 '1700003E16Rik' mRNA 558 554 513 15.46 15.12 15.07 3.66 3.31 3.01 15.21666667 3.326666667 152 134 121 541.6666667 135.6666667 4.69E-44 -2.00906986 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71838 71838 'Phf7' mRNA 206 152 173 5.97 4.21 5.3 5.17 5.82 5.79 5.16 5.593333333 211 223 219 177 217.6666667 0.173825768 0.2864808 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck GO:0046872///metal ion binding GO:0008150///biological_process 71839 71839 'Osgin1' mRNA 43 47 59 1.23 1.34 1.8 4.48 6.13 5.54 1.456666667 5.383333333 179 240 214 49.66666667 211 6.60E-17 2.073305543 GO:0005575///cellular_component GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030334///regulation of cell migration+++GO:0040008///regulation of growth+++GO:0042127///regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process 71840 71840 'Tekt4' mRNA 424 431 444 16.34 16.41 18.21 1.77 1.41 1.07 16.98666667 1.416666667 52 41 30 433 41 3.65E-62 -3.415723797 GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097225///sperm midpiece+++GO:0097228///sperm principal piece GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0060378///regulation of brood size 71843 71843 'R3hcc1' mRNA 595 601 532 19.03 18.69 18.17 15.72 15.83 17.3 18.63 16.28333333 556 560 593 576 569.6666667 0.863090843 -0.025581632 GO:0003674///molecular_function+++GO:0003676///nucleic acid binding GO:0008150///biological_process 71844 71844 'Nupl1' mRNA 862 954 890 11.73 12.79 12.94 11.44 11.41 11.13 12.48666667 11.32666667 965 951 909 902 941.6666667 0.686868462 0.050277041 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006913///nucleocytoplasmic transport+++GO:0015031///protein transport+++GO:0042306///regulation of protein import into nucleus+++GO:0051028///mRNA transport 71846 71846 'Syce2' mRNA 51 66 68 3.43 4.57 4.88 7.7 8.02 8.06 4.293333333 7.926666667 127 127 129 61.66666667 127.6666667 8.84E-05 1.035654768 GO:0000795///synaptonemal complex+++GO:0000801///central element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle 71853 71853 'Pdia6' mRNA 5927 6293 6042 156.08 163.23 168.79 244.8 263.03 247.44 162.7 251.7566667 10689 11213 10458 6087.333333 10786.66667 7.46E-43 0.813668832 04141///Protein processing in endoplasmic reticulum GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0042470///melanosome GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity GO:0030168///platelet activation+++GO:0070527///platelet aggregation+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response 71854 71854 'Dpep3' mRNA 0 1 3 0 0.03 0.11 0.06 0.03 0.25 0.046666667 0.113333333 2 1 8 1.333333333 3.666666667 0.493007796 1.418018664 GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:0070573///metallodipeptidase activity GO:0006508///proteolysis 71856 71856 'Wfdc3' mRNA 186 190 189 4.79 5.15 5.05 7.04 11.51 10.72 4.996666667 9.756666667 146 216 194 188.3333333 185.3333333 0.903717979 -0.032296568 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019731///antibacterial humoral response+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0052547///regulation of peptidase activity 71860 71860 'Cfap52' mRNA 1499 1476 1575 38.69 37.61 43.31 5.64 5.24 5.74 39.87 5.54 250 226 246 1516.666667 240.6666667 7.80E-139 -2.670429443 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0061966///establishment of left/right asymmetry 71862 71862 'Gpr160' mRNA 267 235 192 7.56 6.24 5.46 9.22 9.94 10.39 6.42 9.85 373 395 405 231.3333333 391 1.12E-06 0.750383114 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 71864 71864 'Fam217a' mRNA 0 0 4 0 0 0.1 0.09 0 0.02 0.033333333 0.036666667 4 0 1 1.333333333 1.666666667 0.943432254 0.224619552 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 71865 71865 'Fbxo30' mRNA 379.03 421.51 274.97 5.14 5.21 3.62 4.43 5.7 6.15 4.656666667 5.426666667 476.91 464.95 534.17 358.5033333 492.01 0.003109736 0.452636022 GO:0005575///cellular_component GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process 71868 71868 'Thegl' mRNA 35 36 21 1.19 1.2 0.75 0.15 0.18 0.06 1.046666667 0.13 5 6 2 30.66666667 4.333333333 5.07E-05 -2.824532096 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71870 71870 'Cfap45' mRNA 782 781 732 24.61 24.31 24.34 4.15 4.54 4.24 24.42 4.31 152 162 151 765 155 6.46E-75 -2.313941417 GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005930///axoneme+++GO:0097728///9+0 motile cilium+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function+++GO:0016208///AMP binding GO:0030317///flagellated sperm motility+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:0061966///establishment of left/right asymmetry+++GO:0090660///cerebrospinal fluid circulation 71872 71872 'Aox4' mRNA 0 0 3 0 0 0.03 0.02 0.03 0 0.01 0.016666667 2 3 0 1 1.666666667 0.849222236 0.666943036 "00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00380///Tryptophan metabolism+++00750///Vitamin B6 metabolism+++00760///Nicotinate and nicotinamide metabolism+++00830///Retinol metabolism+++00982///Drug metabolism - cytochrome P450+++04630///JAK-STAT signaling pathway" GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0004031///aldehyde oxidase activity+++GO:0005506///iron ion binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0030151///molybdenum ion binding+++GO:0042803///protein homodimerization activity+++GO:0043546///molybdopterin cofactor binding+++GO:0046872///metal ion binding+++GO:0050250///retinal oxidase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0071949///FAD binding+++GO:0102797///geranial:oxygen oxidoreductase activity+++GO:0102798///heptaldehyde:oxygen oxidoreductase activity" GO:0017144///drug metabolic process+++GO:0022900///electron transport chain 71874 71874 'Mab21l4' mRNA 22 33 21 0.59 0.94 0.56 0.62 0.61 0.75 0.696666667 0.66 29 27 31 25.33333333 29 0.766285578 0.188738165 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71876 71876 'Cenpu' mRNA 20.07 45.3 23.2 0.32 0.7 0.39 1.08 1.21 1.01 0.47 1.1 79.06 86.54 71.22 29.52333333 78.94 2.01E-04 1.4196658 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0034451///centriolar satellite" GO:0005515///protein binding GO:0043009///chordate embryonic development 71877 71877 'Efhc1' mRNA 432 506 442 11.03 12.72 11.97 2.49 2.07 1.9 11.90666667 2.153333333 112 91 83 460 95.33333333 1.75E-42 -2.282802968 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0043025///neuronal cell body+++GO:0072686///mitotic spindle GO:0005509///calcium ion binding+++GO:0008022///protein C-terminus binding+++GO:0043014///alpha-tubulin binding GO:0000281///mitotic cytokinesis+++GO:0006874///cellular calcium ion homeostasis+++GO:0007052///mitotic spindle organization+++GO:0021795///cerebral cortex cell migration+++GO:0043065///positive regulation of apoptotic process+++GO:0051302///regulation of cell division+++GO:0060285///cilium-dependent cell motility 71878 71878 'Fam83d' mRNA 4 1 5 0.09 0.03 0.13 1.48 2.26 1.73 0.083333333 1.823333333 69 100 71 3.333333333 80 1.57E-14 4.571876354 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole GO:0008017///microtubule binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding GO:0001837///epithelial to mesenchymal transition+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0016477///cell migration+++GO:0032006///regulation of TOR signaling+++GO:0042176///regulation of protein catabolic process+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1902480///protein localization to mitotic spindle+++GO:1902808///positive regulation of cell cycle G1/S phase transition 71881 71881 'Apmap' mRNA 1339.37 1486.08 1414.31 32.99 35.9 37.24 35.01 37.53 35.08 35.37666667 35.87333333 1624 1682.04 1575.1 1413.253333 1627.046667 0.030154023 0.191568639 GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004064///arylesterase activity+++GO:0016844///strictosidine synthase activity GO:0009058///biosynthetic process 71883 71883 'Coq2' mRNA 679 756 262 21.59 24.01 8.77 9.91 12.46 14.41 18.12333333 12.26 366 421 491 565.6666667 426 0.472015714 -0.397527607 00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane "GO:0002083///4-hydroxybenzoate decaprenyltransferase activity+++GO:0002094///polyprenyltransferase activity+++GO:0004659///prenyltransferase activity+++GO:0008412///4-hydroxybenzoate octaprenyltransferase activity+++GO:0016740///transferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0047293///4-hydroxybenzoate nonaprenyltransferase activity" GO:0006071///glycerol metabolic process+++GO:0006744///ubiquinone biosynthetic process+++GO:0008299///isoprenoid biosynthetic process 71884 71884 'Chit1' mRNA 1 0 2 0.04 0 0.07 0.06 0.06 0.11 0.036666667 0.076666667 2 2 4 1 2.666666667 0.546802432 1.378136765 00520///Amino sugar and nucleotide sugar metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004568///chitinase activity+++GO:0008061///chitin binding+++GO:0008843///endochitinase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0000272///polysaccharide catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0008152///metabolic process 71885 71885 'Faap100' mRNA 964 914 832 16.61 15.5 15.21 9.41 10.75 10.05 15.77333333 10.07 628 701 650 903.3333333 659.6666667 7.16E-06 -0.46253946 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0043240///Fanconi anaemia nuclear complex GO:0003674///molecular_function+++GO:0003677///DNA binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008150///biological_process+++GO:0036297///interstrand cross-link repair 71886 71886 '2310002L09Rik' mRNA 0 0 1 0 0 0.03 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0031032///actomyosin structure organization 71887 71887 'Ppm1j' mRNA 61 43 36 2.05 1.43 1.27 4.1 3.25 3.32 1.583333333 3.556666667 140 109 111 46.66666667 120 3.95E-06 1.353375793 GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation 71889 71889 'Epn3' mRNA 2692 2371 2688 38.09 32.95 40.5 17.27 14.79 16.04 37.18 16.03333333 1421 1185 1276 2583.666667 1294 1.83E-29 -1.013777216 04144///Endocytosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005938///cell cortex+++GO:0019897///extrinsic component of plasma membrane+++GO:0030125///clathrin vesicle coat+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0030276///clathrin binding+++GO:1990175///EH domain binding GO:0006897///endocytosis 71890 71890 'Mad2l2' mRNA 783 840 706 38.5 41.3 37.05 51.67 57.3 55.43 38.95 54.8 1183 1276 1239 776.3333333 1232.666667 5.45E-13 0.658566952 04110///Cell cycle+++04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++05100///Bacterial invasion of epithelial cells GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016035///zeta DNA polymerase complex GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001558///regulation of cell growth+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042177///negative regulation of protein catabolic process+++GO:0042772///DNA damage response, signal transduction resulting in transcription+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045830///positive regulation of isotype switching+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051301///cell division+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining" 71891 71891 'Cdadc1' mRNA 1718.31 1710.21 1697.33 33.94 33.01 36.38 23.99 24.18 24.44 34.44333333 24.20333333 1351.7 1350.27 1427.52 1708.616667 1376.496667 5.00E-05 -0.32420693 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004126///cytidine deaminase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047844///deoxycytidine deaminase activity+++GO:0061676///importin-alpha family protein binding GO:0009972///cytidine deamination+++GO:0070383///DNA cytosine deamination 71893 71893 'Noxo1' mRNA 1406.26 1378.8 1298.77 68.17 64.57 64.27 54.28 49.18 49.55 65.67 51.00333333 1256.03 1154.86 1160.61 1361.276667 1190.5 0.01438829 -0.205004005 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043020///NADPH oxidase complex GO:0008289///lipid binding+++GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0019899///enzyme binding+++GO:0035091///phosphatidylinositol binding+++GO:0060090///molecular adaptor activity GO:0006801///superoxide metabolic process+++GO:0022617///extracellular matrix disassembly+++GO:0042554///superoxide anion generation+++GO:0050790///regulation of catalytic activity 71897 71897 'Lypd6b' mRNA 439 486 413 12.43 13.52 12.41 2.4 3.03 3.03 12.78666667 2.82 96 117 123 446 112 1.10E-34 -2.001804297 04080///Neuroactive ligand-receptor interaction GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0030548///acetylcholine receptor regulator activity 71898 71898 'Apol9b' mRNA 7.47 26.91 19.72 0.17 0.86 0.74 4.07 3.57 2.9 0.59 3.513333333 136.69 107.7 92.88 18.03333333 112.4233333 7.57E-12 2.673019671 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0042157///lipoprotein metabolic process 71900 71900 'Tmem106b' mRNA 2130 2328 2092 18.57 19.96 19.35 21.48 19.5 20.79 19.29333333 20.59 2837 2516 2659 2183.333333 2670.666667 7.13E-05 0.278912037 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane GO:0051117///ATPase binding GO:0007040///lysosome organization+++GO:0007041///lysosomal transport+++GO:0007042///lysosomal lumen acidification+++GO:0032418///lysosome localization+++GO:0048813///dendrite morphogenesis+++GO:0051345///positive regulation of hydrolase activity+++GO:1900006///positive regulation of dendrite development+++GO:1905146///lysosomal protein catabolic process+++GO:1905671///regulation of lysosome organization 71901 71901 'Fam219a' mRNA 70 96 105 1.14 1.53 1.8 2.66 2.56 2.32 1.49 2.513333333 190 178 160 90.33333333 176 7.34E-05 0.945285086 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 71902 71902 'Cand1' mRNA 1765 1660 1633 11.31 10.45 11.09 10.32 10.44 10.72 10.95 10.49333333 1856 1834 1867 1686 1852.333333 0.126806732 0.124178758 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex GO:0005515///protein binding+++GO:0017025///TBP-class protein binding "GO:0010265///SCF complex assembly+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0043086///negative regulation of catalytic activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly" 71903 71903 'Ces2f' mRNA 87.53 84.23 82.67 1.4 0.98 1.27 0.24 0.23 0.37 1.216666667 0.28 23.63 22.02 35.01 84.81 26.88666667 1.76E-06 -1.672208633 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process 71904 71904 'Paqr7' mRNA 603 603.7 610 14.29 14.07 15.11 21.06 18.55 20.75 14.49 20.12 1024 897.85 978.95 605.5666667 966.9333333 2.58E-11 0.661262814 05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003707///steroid hormone receptor activity+++GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0048477///oogenesis+++GO:0048545///response to steroid hormone 71907 71907 'Serpina9' mRNA 1 5 1 0.03 0.17 0.04 0.18 0.06 0.09 0.08 0.11 6 2 3 2.333333333 3.666666667 0.740213982 0.651292902 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 71908 71908 'Cldn23' mRNA 186 175 205 5.77 5.35 6.75 10.12 11.01 10.88 5.956666667 10.67 375 398 390 188.6666667 387.6666667 6.14E-11 1.024799615 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0005198///structural molecule activity+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 71909 71909 'Haus5' mRNA 425 412 430 10.92 10.42 11.72 8.42 9.15 9 11.02 8.856666667 377 400 390 422.3333333 389 0.398604079 -0.131092857 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 71910 71910 'Plpp5' mRNA 458 467 462 18.21 18.33 19.57 25.35 23.98 23.04 18.70333333 24.12333333 733 674 646 462.3333333 684.3333333 8.04E-07 0.552769737 00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000810///diacylglycerol diphosphate phosphatase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042577///lipid phosphatase activity GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0046839///phospholipid dephosphorylation 71911 71911 'Bdh1' mRNA 338 337 312 5.94 5.82 5.8 7.07 7.49 7.28 5.853333333 7.28 463 479 462 329 468 1.12E-04 0.498043774 00650///Butanoate metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0099617///matrix side of mitochondrial inner membrane GO:0003824///catalytic activity+++GO:0003858///3-hydroxybutyrate dehydrogenase activity+++GO:0005543///phospholipid binding+++GO:0016491///oxidoreductase activity GO:0008152///metabolic process 71912 71912 'Jsrp1' mRNA 4 6 5 0.22 0.33 0.3 0.73 1.15 1.06 0.283333333 0.98 15 23 21 5 19.66666667 0.010313293 1.968475076 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0033017///sarcoplasmic reticulum membrane GO:0005515///protein binding GO:0003009///skeletal muscle contraction+++GO:0006941///striated muscle contraction+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0072657///protein localization to membrane 71913 71913 'Tmem79' mRNA 344 421 405 9.14 10.95 11.1 8.48 9.8 10.07 10.39666667 9.45 360 412 423 390 398.3333333 0.924287695 0.01874993 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032588///trans-Golgi network membrane GO:0042802///identical protein binding GO:0002070///epithelial cell maturation+++GO:0031069///hair follicle morphogenesis+++GO:0042335///cuticle development+++GO:0045055///regulated exocytosis+++GO:0045684///positive regulation of epidermis development+++GO:0061436///establishment of skin barrier+++GO:0070268///cornification 71914 71914 'Antxr2' mRNA 528 576 637 7.51 8.06 9.61 11.5 11.79 11.33 8.393333333 11.54 931 932 888 580.3333333 917 1.73E-08 0.644664668 04621///NOD-like receptor signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding GO:0022414///reproductive process+++GO:1901998///toxin transport 71916 71916 'Dus4l' mRNA 13 25 6 0.45 0.85 0.22 0.37 0.09 0.1 0.506666667 0.186666667 13 3 3 14.66666667 6.333333333 0.220946205 -1.213726287 GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0017150///tRNA dihydrouridine synthase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0002943///tRNA dihydrouridine synthesis+++GO:0008033///tRNA processing 71918 71918 'Zcchc24' mRNA 473 532 504 5.53 6.12 6.25 13.16 11.21 12.38 5.966666667 12.25 1296 1078 1181 503 1185 1.69E-33 1.22271904 GO:0005575///cellular_component GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0014013///regulation of gliogenesis 71919 71919 'Rpap3' mRNA 540 657 637 13.44 16.43 16.85 10.52 9.22 8.81 15.57333333 9.516666667 482 410 391 611.3333333 427.6666667 7.85E-05 -0.530430349 GO:0005829///cytosol+++GO:0097255///R2TP complex GO:0003674///molecular_function GO:0008150///biological_process 71923 71923 'Borcs6' mRNA 731 711 350 23.38 22.41 11.87 11.8 18.99 18.72 19.22 16.50333333 424 666 651 597.3333333 580.3333333 0.950866287 -0.033021527 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0099078///BORC complex GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0032418///lysosome localization 71924 71924 'Tube1' mRNA 69.64 78.11 101.68 0.92 1.01 1.6 1.08 1.19 0.84 1.176666667 1.036666667 87.93 79.6 68 83.14333333 78.51 0.798887621 -0.104047807 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007017///microtubule-based process 71927 71927 'Itfg1' mRNA 3146 3366 3313 51.13 53.82 57.11 46.59 48.98 46.72 54.02 47.43 3299 3388 3204 3275 3297 0.981116568 -0.002907658 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0008150///biological_process 71929 71929 'Tmem123' mRNA 1358 1500 1183 26.06 28.4 24.23 29.93 34.88 34.03 26.23 32.94666667 1794 2042 1963 1347 1933 9.67E-09 0.514552199 GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0070267///oncosis 71932 71932 'Ephx3' mRNA 4 12 15 0.16 0.28 0.65 0.17 0.3 0.24 0.363333333 0.236666667 5 14 8 10.33333333 9 0.863090843 -0.216396482 05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0004301///epoxide hydrolase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0097176///epoxide metabolic process 71934 71934 'Car13' mRNA 1490 1614 1387 36.38 38.81 35.93 75.65 71.98 73.08 37.04 73.57 3563 3310 3332 1497 3401.666667 1.19E-72 1.173785342 00910///Nitrogen metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process 71939 71939 'Apol6' mRNA 5.04 6 7.71 0.14 0.15 0.22 0.18 0.13 0.25 0.17 0.186666667 8 6.02 10.57 6.25 8.196666667 0.748006124 0.397463623 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008289///lipid binding GO:0006869///lipid transport+++GO:0008150///biological_process+++GO:0042157///lipoprotein metabolic process 71941 71941 'Cars2' mRNA 452 413 425 13.71 12.28 13.61 11.21 10.78 10.91 13.2 10.96666667 424 401 403 430 409.3333333 0.605999071 -0.083698455 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004817///cysteine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006423///cysteinyl-tRNA aminoacylation 71943 71943 'Tom1l1' mRNA 508.22 576.61 509.44 13.48 15.09 14.43 13.87 13.86 13.89 14.33333333 13.87333333 602.53 583.8 580.44 531.4233333 588.9233333 0.286633278 0.137036612 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0030295///protein kinase activator activity+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0015031///protein transport+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0045839///negative regulation of mitotic nuclear division 71946 71946 'Endod1' mRNA 1419 1332 1446 17.07 15.73 18.42 22.59 22.2 23.36 17.07333333 22.71666667 2165 2074 2162 1399 2133.666667 1.41E-13 0.594884702 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 71947 71947 'Tmem94' mRNA 902 902 671 9.65 9.53 7.64 5.84 6.32 6.54 8.94 6.233333333 627 665 681 825 657.6666667 0.005430869 -0.33230501 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 71949 71949 'Cers5' mRNA 2700 2734 2667 76.44 76.25 80.1 46.86 47.52 47.78 77.59666667 47.38666667 1903 1884 1878 2700.333333 1888.333333 2.68E-15 -0.52811627 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process 71950 71950 'Nanog' mRNA 35.8 44 64.13 0.99 1.21 1.87 1.05 1.23 1.13 1.356666667 1.136666667 45.06 50.51 46.56 47.97666667 47.37666667 0.935098771 -0.042120018 04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001010///RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001710///mesodermal cell fate commitment+++GO:0001714///endodermal cell fate specification+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation+++GO:0008406///gonad development+++GO:0009790///embryo development+++GO:0009880///embryonic pattern specification+++GO:0010033///response to organic substance+++GO:0010454///negative regulation of cell fate commitment+++GO:0010468///regulation of gene expression+++GO:0017145///stem cell division+++GO:0019827///stem cell population maintenance+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032526///response to retinoic acid+++GO:0035019///somatic stem cell population maintenance+++GO:0042664///negative regulation of endodermal cell fate specification+++GO:0043697///cell dedifferentiation+++GO:0045595///regulation of cell differentiation+++GO:0045596///negative regulation of cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048863///stem cell differentiation+++GO:2000035///regulation of stem cell division+++GO:2000648///positive regulation of stem cell proliferation" 71951 71951 'Gpc2' mRNA 516 529 356 8.02 7.99 5.79 2.34 1.69 2.32 7.266666667 2.116666667 174 118 168 467 153.3333333 1.74E-19 -1.612986293 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse+++GO:0046658///anchored component of plasma membrane+++GO:0062023///collagen-containing extracellular matrix GO:0007224///smoothened signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0016477///cell migration+++GO:0030182///neuron differentiation+++GO:1905475///regulation of protein localization to membrane 71952 71952 'Riox1' mRNA 147 142 29 3.51 3.34 0.73 1.6 1.51 2.12 2.526666667 1.743333333 77 71 99 106 82.33333333 0.488495911 -0.349793021 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030685///nucleolar preribosome "GO:0003723///RNA binding+++GO:0005506///iron ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)" "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0034720///histone H3-K4 demethylation+++GO:0042254///ribosome biogenesis+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070544///histone H3-K36 demethylation" 71954 71954 'Suds3' mRNA 689 698 338 15.39 15.47 7.67 5.92 5.08 6.04 12.84333333 5.68 303.82 263 310 575 292.2733333 9.04E-07 -0.975355259 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016580///Sin3 complex+++GO:0016604///nuclear body+++GO:0070822///Sin3-type complex GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042826///histone deacetylase binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001835///blastocyst hatching+++GO:0006325///chromatin organization+++GO:0006915///apoptotic process+++GO:0016575///histone deacetylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated" 71955 71955 'Ist1' mRNA 2099.67 2119.58 2108.49 50.7 50.55 54.13 60.41 60.25 60.1 51.79333333 60.25333333 2858.36 2768.63 2767.54 2109.246667 2798.176667 4.52E-09 0.395225693 04144///Endocytosis GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0090543///Flemming body GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0090541///MIT domain binding GO:0007049///cell cycle+++GO:0008104///protein localization+++GO:0009838///abscission+++GO:0015031///protein transport+++GO:0019076///viral release from host cell+++GO:0045184///establishment of protein localization+++GO:0045862///positive regulation of proteolysis+++GO:0046745///viral capsid secondary envelopment+++GO:0048672///positive regulation of collateral sprouting+++GO:0051301///cell division+++GO:0061640///cytoskeleton-dependent cytokinesis 71956 71956 'Rnf135' mRNA 478 465 481 13.93 13.42 14.89 17.36 16.48 15.36 14.08 16.4 680 633 586 474.6666667 633 7.35E-04 0.401716511 GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0039552///RIG-I binding+++GO:0042802///identical protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0032728///positive regulation of interferon-beta production+++GO:0039529///RIG-I signaling pathway+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0051260///protein homooligomerization+++GO:0070534///protein K63-linked ubiquitination 71957 71957 'Ints11' mRNA 848.32 906.69 842.44 20.35 21.42 21.43 23.49 24.3 24.49 21.06666667 24.09333333 1126.77 1136.48 1136.62 865.8166667 1133.29 2.23E-05 0.377277361 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032039///integrator complex GO:0004521///endoribonuclease activity+++GO:0016787///hydrolase activity "GO:0016180///snRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 71960 71960 'Myh14' mRNA 2247 2426 2318 18.23 19.44 20 13.55 12.58 13.16 19.22333333 13.09666667 1917 1738 1798 2330.333333 1817.666667 3.88E-07 -0.371371207 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042641///actomyosin+++GO:0043209///myelin sheath+++GO:0097513///myosin II filament GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0051015///actin filament binding GO:0003009///skeletal muscle contraction+++GO:0007519///skeletal muscle tissue development+++GO:0007605///sensory perception of sound+++GO:0008360///regulation of cell shape+++GO:0019228///neuronal action potential+++GO:0030048///actin filament-based movement+++GO:0031032///actomyosin structure organization+++GO:0070584///mitochondrion morphogenesis+++GO:0071625///vocalization behavior 71962 71962 'Castor1' mRNA 253 302 283 9.3 11.04 11.1 13.23 12.04 11.48 10.48 12.25 411 363 343 279.3333333 372.3333333 0.009807877 0.40116241 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0061700///GATOR2 complex GO:0034618///arginine binding+++GO:0042802///identical protein binding GO:1902531///regulation of intracellular signal transduction+++GO:1903432///regulation of TORC1 signaling+++GO:1903577///cellular response to L-arginine+++GO:1904262///negative regulation of TORC1 signaling 71963 71963 'Cdca4' mRNA 433 482 486 11.52 12.69 13.91 18.26 16.79 18.91 12.70666667 17.98666667 796 705.74 797.77 467 766.5033333 1.06E-09 0.69982843 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0140110///transcription regulator activity "GO:0045815///positive regulation of gene expression, epigenetic+++GO:0048096///chromatin-mediated maintenance of transcription" 71966 71966 'Nkiras2' mRNA 1110.01 1065.39 1091.1 30.18 28.81 31.98 32.35 31.24 31.41 30.32333333 31.66666667 1362.59 1288 1286.65 1088.833333 1312.413333 0.00348518 0.256157276 GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0032794///GTPase activating protein binding GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0032484///Ral protein signal transduction+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043129///surfactant homeostasis+++GO:0048286///lung alveolus development 71967 71967 'Mageb16' mRNA 9 10 5 0.3 0.33 0.18 0.2 0.09 0.21 0.27 0.166666667 7 3 7 8 5.666666667 0.684710191 -0.502096001 GO:0005634///nucleus GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 71968 71968 'Wdr73' mRNA 689 674 663 18.05 17.35 18.34 12.35 12.93 12.56 17.91333333 12.61333333 539 545 526 675.3333333 536.6666667 0.001803309 -0.343333855 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0032154///cleavage furrow GO:0003674///molecular_function GO:0006997///nucleus organization+++GO:0031122///cytoplasmic microtubule organization+++GO:0043066///negative regulation of apoptotic process 71970 71970 'Zbed5' mRNA 67.76 76.7 83.67 1.52 1.68 2.28 0.92 0.91 0.7 1.826666667 0.843333333 48.23 37.4 34.84 76.04333333 40.15666667 0.006224853 -0.942996515 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion GO:0008150///biological_process 71971 71971 'Zswim1' mRNA 790 964 859 16.19 19.45 18.68 11.28 12.46 13.07 18.10666667 12.27 633 683 710 871 675.3333333 9.23E-04 -0.377622177 GO:0005634///nucleus GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 71972 71972 'Dnmbp' mRNA 2008.83 2088.79 1718.32 15.9 16.51 14.23 10.56 12.4 11.3 15.54666667 11.42 1526.75 1714.1 1591.4 1938.646667 1610.75 0.001458892 -0.274437316 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0007568///aging+++GO:0008360///regulation of cell shape+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 71973 71973 'Rbpms2' mRNA 144 114 139 4.36 3.4 4.47 5.04 6.19 4.66 4.076666667 5.296666667 192 230 173 132.3333333 198.3333333 0.01025355 0.570598451 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0007275///multicellular organism development+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051151///negative regulation of smooth muscle cell differentiation 71974 71974 'Prmt3' mRNA 716 781 780 15.99 17.17 18.48 12.72 13.68 12.19 17.21333333 12.86333333 655 688 608 759 650.3333333 0.045389566 -0.235763762 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0043022///ribosome binding+++GO:0046872///metal ion binding+++GO:0072341///modified amino acid binding "GO:0006479///protein methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032259///methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0060997///dendritic spine morphogenesis+++GO:1900053///negative regulation of retinoic acid biosynthetic process" 71978 71978 'Ppp2r2a' mRNA 1715 1688 1696 22.87 22.18 24.01 21.37 20.95 21.49 23.02 21.27 1841 1764 1793 1699.666667 1799.333333 0.438626142 0.069478035 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0019888///protein phosphatase regulator activity+++GO:0044877///protein-containing complex binding+++GO:0048156///tau protein binding+++GO:0051721///protein phosphatase 2A binding GO:0006470///protein dephosphorylation+++GO:0043278///response to morphine+++GO:0050790///regulation of catalytic activity+++GO:0070262///peptidyl-serine dephosphorylation 71981 71981 'Tdrd12' mRNA 76 68 91 0.98 1.11 1.28 0.23 0.1 0.37 1.123333333 0.233333333 13 12 23 78.33333333 16 1.61E-08 -2.309479342 GO:0005829///cytosol+++GO:1990923///PET complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0007140///male meiotic nuclear division+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle 71982 71982 'Snx10' mRNA 304 397 310 6.82 8.77 7.38 21.06 18.81 21.46 7.656666667 20.44333333 1079 941 1062 337 1027.333333 1.88E-43 1.597963653 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031313///extrinsic component of endosome membrane+++GO:0090651///apical cytoplasm GO:0005545///1-phosphatidylinositol binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0051117///ATPase binding GO:0001696///gastric acid secretion+++GO:0006886///intracellular protein transport+++GO:0006897///endocytosis+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0030316///osteoclast differentiation+++GO:0035630///bone mineralization involved in bone maturation+++GO:0044691///tooth eruption+++GO:0045453///bone resorption+++GO:0046849///bone remodeling+++GO:0055074///calcium ion homeostasis+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:0071539///protein localization to centrosome+++GO:0097178///ruffle assembly+++GO:1990830///cellular response to leukemia inhibitory factor 71983 71983 'Tmco6' mRNA 712 672 606 22.41 20.7 20.01 8.1 9.31 8.33 21.04 8.58 297 335 296 663.3333333 309.3333333 8.50E-20 -1.109453735 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0008150///biological_process 71984 71984 'Sars2' mRNA 391 394 381 11.98 11.91 12.34 11.81 12.62 13.82 12.07666667 12.75 435 465 496 388.6666667 465.3333333 0.072686045 0.248865799 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004828///serine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006434///seryl-tRNA aminoacylation+++GO:0070158///mitochondrial seryl-tRNA aminoacylation+++GO:0097056///selenocysteinyl-tRNA(Sec) biosynthetic process 71985 71985 'Acad10' mRNA 362.2 345.85 309.05 5.85 5.89 5.45 2.95 3.24 2.8 5.73 2.996666667 206.96 236.79 188.62 339.0333333 210.79 1.47E-05 -0.698301814 GO:0005739///mitochondrion "GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016787///hydrolase activity+++GO:0050660///flavin adenine dinucleotide binding" 71986 71986 'Ddx28' mRNA 326 338 331 10 10.21 10.77 12.72 11.81 12.1 10.32666667 12.21 477 432 439 331.6666667 449.3333333 0.001370365 0.425170926 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding GO:0042254///ribosome biogenesis+++GO:1902775///mitochondrial large ribosomal subunit assembly 71988 71988 'Esco2' mRNA 3 3 2 0.06 0.06 0.04 1.6 1.61 1.81 0.053333333 1.673333333 97 95 106 2.666666667 99.33333333 9.46E-18 5.209862417 GO:0000785///chromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005721///pericentric heterochromatin+++GO:0005794///Golgi apparatus+++GO:0010369///chromocenter+++GO:0030054///cell junction+++GO:0035861///site of double-strand break "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006275///regulation of DNA replication+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007062///sister chromatid cohesion+++GO:0034421///post-translational protein acetylation+++GO:0071168///protein localization to chromatin 71989 71989 'Rpusd4' mRNA 389 452 361 12.48 14.29 12.29 15.44 15.36 18.29 13.02 16.36333333 553 537 634 400.6666667 574.6666667 8.00E-05 0.511756568 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:1990400///mitochondrial ribosomal large subunit rRNA binding GO:0000455///enzyme-directed rRNA pseudouridine synthesis+++GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0070131///positive regulation of mitochondrial translation+++GO:0070902///mitochondrial tRNA pseudouridine synthesis 71990 71990 'Ddx54' mRNA 1178 1243 1247 16.19 16.8 18.18 16.46 17.71 19.23 17.05666667 17.8 1378 1449 1560 1222.666667 1462.333333 0.009973505 0.245966688 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0030331///estrogen receptor binding "GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0016070///RNA metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated" 71991 71991 'Ercc8' mRNA 243 216 188 6.86 5.92 5.51 5.93 4.87 4.35 6.096666667 5.05 240 197 176 215.6666667 204.3333333 0.727489395 -0.088480898 03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis GO:0000109///nucleotide-excision repair complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0043204///perikaryon+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding GO:0000012///single strand break repair+++GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0009411///response to UV+++GO:0010165///response to X-ray+++GO:0010996///response to auditory stimulus+++GO:0014070///response to organic cyclic compound+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045739///positive regulation of DNA repair+++GO:0051865///protein autoubiquitination+++GO:0090262///regulation of transcription-coupled nucleotide-excision repair+++GO:0097680///double-strand break repair via classical nonhomologous end joining 71994 71994 'Cnn3' mRNA 11867 12480 12181 337.26 349.42 367.25 325.14 319.28 312.36 351.31 318.9266667 13153 12609 12230 12176 12664 0.534530734 0.043689066 GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0015629///actin cytoskeleton+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0008017///microtubule binding GO:0030855///epithelial cell differentiation+++GO:0031032///actomyosin structure organization+++GO:0032780///negative regulation of ATPase activity 71995 71995 'Erv3' mRNA 3 1 5 0.05 0.02 0.09 0 0 0.06 0.053333333 0.02 0 0 4 3 1.333333333 0.612251631 -1.201695036 GO:0005575///cellular_component GO:0003674///molecular_function 71997 71997 'Smg9' mRNA 717.47 744.28 653.23 14.57 14.24 13.83 12.6 12.05 11.57 14.21333333 12.07333333 691.97 637.09 623.62 704.9933333 650.8933333 0.281543194 -0.126364108 GO:0042802///identical protein binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001654///eye development+++GO:0001701///in utero embryonic development+++GO:0007420///brain development+++GO:0007507///heart development" 71998 71998 'Slc25a35' mRNA 606.74 531.26 518.78 16.13 13.39 14.56 13.01 9.37 11.5 14.69333333 11.29333333 539.54 375.45 470.43 552.26 461.8066667 0.068956666 -0.271655287 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane 71999 71999 'Fbxo22' mRNA 892.88 913.84 942.72 23.29 23.3 25.91 25.7 26.94 26.9 24.16666667 26.51333333 1116.01 1140.54 1136.77 916.48 1131.106667 0.002365986 0.291276678 05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030018///Z disc GO:0005515///protein binding GO:0000209///protein polyubiquitination+++GO:0006913///nucleocytoplasmic transport+++GO:0009267///cellular response to starvation+++GO:0010830///regulation of myotube differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0048742///regulation of skeletal muscle fiber development+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 72000 72000 'Lmntd2' mRNA 205.93 187 199.57 4.31 3.74 4.24 2.14 1.67 2.26 4.096666667 2.023333333 113 93.47 129.14 197.5 111.87 8.96E-05 -0.832859987 GO:0005638///lamin filament GO:0030527///structural constituent of chromatin "GO:0010847///regulation of chromatin assembly+++GO:0048026///positive regulation of mRNA splicing, via spliceosome" 72002 72002 'Slc39a5' mRNA 0 1 0 0 0.04 0 0 0.08 0 0.013333333 0.026666667 0 3 0 0.333333333 1 0.7490626 1.492233064 05010///Alzheimer disease+++05012///Parkinson disease GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity "GO:0001654///eye development+++GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0030509///BMP signaling pathway+++GO:0034224///cellular response to zinc ion starvation+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0055085///transmembrane transport+++GO:0071578///zinc ion import across plasma membrane" 72003 72003 'Synpr' mRNA 1904 2026 1892 39.72 41.62 41.87 5.36 4.84 4.63 41.07 4.943333333 294 260 247 1940.666667 267 1.47E-200 -2.874024242 GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0017075///syntaxin-1 binding 72007 72007 'Fndc3b' mRNA 1006 1012 836 7.8 7.7 6.94 9.11 9.01 8.85 7.48 8.99 1339 1280 1243 951.3333333 1287.333333 1.08E-06 0.4275451 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016477///cell migration+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0060510///type II pneumocyte differentiation 72008 72008 'Zfyve19' mRNA 811 863 770 26.93 28.27 27.16 23.12 25 22.21 27.45333333 23.44333333 804 838 781.03 814.6666667 807.6766667 0.863090843 -0.0225389 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0090543///Flemming body GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0046872///metal ion binding GO:0007049///cell cycle+++GO:0009838///abscission+++GO:0032466///negative regulation of cytokinesis+++GO:0044878///mitotic cytokinesis checkpoint+++GO:0051301///cell division 72014 72014 'Btbd17' mRNA 1758 1809 1574 36.21 37.9 35.31 12.74 11.92 13.48 36.47333333 12.71333333 733 675 747 1713.666667 718.3333333 4.19E-54 -1.264368281 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 72016 72016 'Tedc2' mRNA 188 191.44 164.08 5.06 4.93 4.67 3.48 3.48 3.96 4.886666667 3.64 152.03 145.61 164 181.1733333 153.88 0.258105107 -0.245622013 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0045880///positive regulation of smoothened signaling pathway 72017 72017 'Cyb5r1' mRNA 1372 1332 1195 43.03 41.21 39.72 35.77 31.43 35.89 41.32 34.36333333 1312 1123 1274 1299.666667 1236.333333 0.420111752 -0.082993601 00520///Amino sugar and nucleotide sugar metabolism GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0016491///oxidoreductase activity+++GO:0071949///FAD binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0016126///sterol biosynthetic process 72018 72018 'Fundc1' mRNA 2354 2363 2334 45.86 44.31 46.61 33.96 34.25 32.12 45.59333333 33.44333333 2040 2006 1859 2350.333333 1968.333333 2.97E-04 -0.268423401 04137///Mitophagy - animal GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0005515///protein binding GO:0000422///autophagy of mitochondrion+++GO:0001666///response to hypoxia+++GO:0006914///autophagy+++GO:0010243///response to organonitrogen compound 72020 72020 'Zfp654' mRNA 294 285 178 2.51 2.37 1.63 1.47 1.22 1.3 2.17 1.33 195 162 167 252.3333333 174.6666667 0.010447417 -0.534723816 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 72022 72022 'Slc35f2' mRNA 92 64 85 2.04 1.47 2.01 1.73 2 2.61 1.84 2.113333333 89 104 130 80.33333333 107.6666667 0.191724533 0.409309235 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0008150///biological_process+++GO:0055085///transmembrane transport 72023 72023 'Cyb561d1' mRNA 388 406 410 4.6 4.82 5.27 3.87 3.53 4.18 4.896666667 3.86 378 341 386 401.3333333 368.3333333 0.38673967 -0.137290312 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding GO:0055085///transmembrane transport 72026 72026 'Trmu' mRNA 405 459 421 15.97 17.93 17.79 10.44 11.91 10.36 17.23 10.90333333 305 339 291 428.3333333 311.6666667 0.001007592 -0.469491439 GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004809///tRNA (guanine-N2-)-methyltransferase activity+++GO:0005524///ATP binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0016783///sulfurtransferase activity+++GO:0046872///metal ion binding+++GO:0061708///tRNA-5-taurinomethyluridine 2-sulfurtransferase GO:0002143///tRNA wobble position uridine thiolation+++GO:0002940///tRNA N2-guanine methylation+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 72027 72027 'Slc39a4' mRNA 15 12 6 0.36 0.3 0.14 0.48 0.3 0.29 0.266666667 0.356666667 22 14 13 11 16.33333333 0.49456165 0.566131507 04978///Mineral absorption+++05010///Alzheimer disease+++05012///Parkinson disease GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0055038///recycling endosome membrane GO:0005385///zinc ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity GO:0006811///ion transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0034224///cellular response to zinc ion starvation+++GO:0055085///transmembrane transport+++GO:0071578///zinc ion import across plasma membrane 72029 72029 'Cnpy3' mRNA 2044 2069 1966 61.6 61.27 62.62 57.33 58.21 56.72 61.83 57.42 2195 2163 2101 2026.333333 2153 0.34294849 0.075951274 GO:0005783///endoplasmic reticulum GO:0005102///signaling receptor binding GO:0002376///immune system process+++GO:0045087///innate immune response 72033 72033 'Tsc22d2' mRNA 1399 1426 1155 7.52 7.53 6.58 5.88 4.55 5.35 7.21 5.26 1259 953 1110 1326.666667 1107.333333 0.010827332 -0.270875875 GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006970///response to osmotic stress 72039 72039 'Mccc1' mRNA 990 1010 997 18.18 18.25 19.42 13.65 13.69 14.14 18.61666667 13.82666667 855 838 858 999 850.3333333 0.010327721 -0.244811161 "00280///Valine, leucine and isoleucine degradation" "GO:0002169///3-methylcrotonyl-CoA carboxylase complex, mitochondrial+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:1905202///methylcrotonoyl-CoA carboxylase complex" GO:0000166///nucleotide binding+++GO:0004485///methylcrotonoyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0016421///CoA carboxylase activity+++GO:0016874///ligase activity+++GO:0046872///metal ion binding GO:0006552///leucine catabolic process 72040 72040 'Cdhr5' mRNA 0 3 1 0 0.08 0.03 0.05 0 0.02 0.036666667 0.023333333 2 0 1 1.333333333 1 0.888097044 -0.427922958 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0031528///microvillus membrane+++GO:0042995///cell projection+++GO:0044214///spanning component of plasma membrane GO:0005509///calcium ion binding+++GO:0008013///beta-catenin binding+++GO:0050839///cell adhesion molecule binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0030154///cell differentiation+++GO:0032532///regulation of microvillus length+++GO:0090675///intermicrovillar adhesion 72041 72041 'Alkbh4' mRNA 387 412 383 12.74 13.4 13.27 11.26 12.5 10.38 13.13666667 11.38 395 429 354 394 392.6666667 0.932123331 -0.01569226 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0070938///contractile ring "GO:0003779///actin binding+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0032451///demethylase activity+++GO:0035516///oxidative DNA demethylase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0006325///chromatin organization+++GO:0006482///protein demethylation+++GO:0031032///actomyosin structure organization+++GO:0035511///oxidative DNA demethylation+++GO:0036090///cleavage furrow ingression+++GO:0070988///demethylation+++GO:0070989///oxidative demethylation+++GO:0080111///DNA demethylation+++GO:1902275///regulation of chromatin organization 72042 72042 'Cotl1' mRNA 345 427 301 12.28 14.99 11.37 57.53 47.65 53.92 12.88 53.03333333 1857 1501 1684 357.6666667 1680.666667 1.83E-91 2.223493821 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0051015///actin filament binding GO:0030833///regulation of actin filament polymerization+++GO:0050832///defense response to fungus 72043 72043 'Sulf2' mRNA 137 151 135 2.01 2.11 2.05 9.53 10.94 9.5 2.056666667 9.99 762 852 744 141 786 3.00E-75 2.469141641 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005886///plasma membrane+++GO:0009986///cell surface GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0005509///calcium ion binding+++GO:0005539///glycosaminoglycan binding+++GO:0008449///N-acetylglucosamine-6-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0002063///chondrocyte development+++GO:0003094///glomerular filtration+++GO:0006790///sulfur compound metabolic process+++GO:0009611///response to wounding+++GO:0010575///positive regulation of vascular endothelial growth factor production+++GO:0014846///esophagus smooth muscle contraction+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0030201///heparan sulfate proteoglycan metabolic process+++GO:0032836///glomerular basement membrane development+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0048706///embryonic skeletal system development+++GO:0051216///cartilage development+++GO:0060348///bone development+++GO:0060384///innervation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097421///liver regeneration+++GO:2000345///regulation of hepatocyte proliferation 72046 72046 'Urgcp' mRNA 1709 1884 1765 22.35 24.39 25.04 16.19 14.41 14.39 23.92666667 14.99666667 1370 1197 1198 1786 1255 2.51E-10 -0.522099782 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005525///GTP binding GO:0007049///cell cycle+++GO:0008150///biological_process 72047 72047 'Ddx42' mRNA 2088 2248 2165 28.99 30.66 31.82 25.1 24.42 24.68 30.49 24.73333333 2081 1987 1986 2167 2018 0.150433624 -0.115404907 03040///Spliceosome GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015030///Cajal body+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0008104///protein localization+++GO:0042981///regulation of apoptotic process 72049 72049 'Tnfrsf13c' mRNA 23 21 10 0.68 0.61 0.31 0.13 0.05 0.13 0.533333333 0.103333333 5 2 5 18 4 0.010828981 -2.171106854 04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04672///Intestinal immune network for IgA production+++05166///Human T-cell leukemia virus 1 infection+++05340///Primary immunodeficiency GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0001782///B cell homeostasis+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002636///positive regulation of germinal center formation+++GO:0030890///positive regulation of B cell proliferation+++GO:0031295///T cell costimulation+++GO:0031296///B cell costimulation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0050776///regulation of immune response 72050 72050 'Poglut2' mRNA 498 452 480 12.02 10.74 12.29 11.71 11.93 12.57 11.68333333 12.07 558 555 580 476.6666667 564.3333333 0.070522798 0.230869232 GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005829///cytosol+++GO:0012505///endomembrane system "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity+++GO:0046527///glucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0018242///protein O-linked glycosylation via serine 72053 72053 'Tmub2' mRNA 1830 1763 1832 46.82 44.99 50.28 44.45 46.89 45.61 47.36333333 45.65 1951.9 2030 1933 1808.333333 1971.633333 0.207649443 0.11180165 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0030433///ubiquitin-dependent ERAD pathway 72054 72054 'Cyp4f18' mRNA 41 34 52 1.33 0.99 1.74 29.34 31.96 30.1 1.353333333 30.46666667 1035 1110 1016 42.33333333 1053.666667 8.32E-162 4.624409178 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008391///arachidonic acid monooxygenase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0018685///alkane 1-monooxygenase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0050051///leukotriene-B4 20-monooxygenase activity+++GO:0052869///arachidonic acid omega-hydroxylase activity+++GO:0052871///alpha-tocopherol omega-hydroxylase activity+++GO:0052872///tocotrienol omega-hydroxylase activity+++GO:0102033///fatty acid omega-hydroxylase activity+++GO:0102207///very long chain fatty acid omega-hydroxylase activity" GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0008217///regulation of blood pressure+++GO:0010430///fatty acid omega-oxidation+++GO:0017144///drug metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0032304///negative regulation of icosanoid secretion+++GO:0032305///positive regulation of icosanoid secretion+++GO:0036101///leukotriene B4 catabolic process+++GO:0042360///vitamin E metabolic process+++GO:0042361///menaquinone catabolic process+++GO:0042376///phylloquinone catabolic process+++GO:0042377///vitamin K catabolic process 72055 72055 'Slc38a10' mRNA 3487 3737 3660 52.14 51.32 57.39 54.58 56.01 59.59 53.61666667 56.72666667 4107 3991 4228 3628 4108.666667 0.017541689 0.166722654 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015171///amino acid transmembrane transporter activity GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport+++GO:0060348///bone development 72056 72056 '1810055G02Rik' mRNA 477 486 533 14.01 14.01 16.61 20.71 20.49 22.19 14.87666667 21.13 815 779 843 498.6666667 812.3333333 9.77E-10 0.689379432 GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0008150///biological_process 72057 72057 'Phf10' mRNA 210.58 211.33 195 4.15 4.59 4.3 5.92 5.4 4.54 4.346666667 5.286666667 288.18 262.49 219 205.6366667 256.5566667 0.099441486 0.308152589 05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071564///npBAF complex GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0007399///nervous system development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 72058 72058 'Igsf5' mRNA 36 42 25 1.36 1.49 1.06 1.86 1.1 1.26 1.303333333 1.406666667 58 31 39 34.33333333 42.66666667 0.56224277 0.304739133 04530///Tight junction+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction GO:0005515///protein binding+++GO:0030165///PDZ domain binding GO:0098609///cell-cell adhesion 72061 72061 'Aopep' mRNA 3693 3912 3485 37.64 38.01 37.44 40.09 36.62 40.18 37.69666667 38.96333333 4272 3889 4126 3696.666667 4095.666667 0.029516884 0.136841121 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis 72065 72065 'Rap2c' mRNA 134 114 108 2.02 1.67 1.76 6.27 5.65 5.73 1.816666667 5.883333333 471 419 420 118.6666667 436.6666667 2.99E-32 1.868467481 04530///Tight junction GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0044291///cell-cell contact zone+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding "GO:0007165///signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032486///Rap protein signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061097///regulation of protein tyrosine kinase activity+++GO:0090557///establishment of endothelial intestinal barrier" 72068 72068 'Cnot2' mRNA 1305 1281 1211 26.32 24.78 25.85 21.58 19.34 21.35 25.65 20.75666667 1225 1108 1197 1265.666667 1176.666667 0.204874582 -0.116919186 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030014///CCR4-NOT complex+++GO:0030015///CCR4-NOT core complex GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0004535///poly(A)-specific ribonuclease activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0001829///trophectodermal cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0031047///gene silencing by RNA+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:2000036///regulation of stem cell population maintenance" 72074 72074 'Anks4b' mRNA 0 1 1 0 0.03 0.03 0 0 0 0.02 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0042995///cell projection GO:0005515///protein binding GO:0030154///cell differentiation+++GO:0034622///cellular protein-containing complex assembly+++GO:0034976///response to endoplasmic reticulum stress+++GO:1904106///protein localization to microvillus+++GO:1904970///brush border assembly 72075 72075 'Ogfr' mRNA 1357 1534 1392 33.33 37.13 36.27 54.82 51.68 54.47 35.57666667 53.65666667 2564 2362 2466 1427.666667 2464 1.75E-26 0.775494714 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane GO:0004985///opioid receptor activity+++GO:0038023///signaling receptor activity GO:0040008///regulation of growth 72077 72077 'Gcnt3' mRNA 0 1 0 0 0.01 0 0.05 0.09 0.12 0.003333333 0.086666667 4 8 10 0.333333333 7.333333333 0.014577214 4.349731565 00512///Mucin type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003829///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008109///N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047225///acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity" GO:0002426///immunoglobulin production in mucosal tissue+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0048729///tissue morphogenesis+++GO:0050892///intestinal absorption+++GO:0060993///kidney morphogenesis 72080 72080 'Sapcd2' mRNA 1 9 0 0.03 0.15 0 0.92 1.05 0.78 0.06 0.916666667 57 65 51 3.333333333 57.66666667 8.89E-10 4.118279962 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0045179///apical cortex GO:0003674///molecular_function GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0051301///cell division+++GO:0090175///regulation of establishment of planar polarity+++GO:0098725///symmetric cell division+++GO:1904777///negative regulation of protein localization to cell cortex 72082 72082 'Cyp2c55' mRNA 2 6 2 0.06 0.18 0.06 0.03 0 0 0.1 0.01 1 0 0 3.333333333 0.333333333 0.164808856 -3.212797081 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042573///retinoic acid metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 72083 72083 'Mzt2' mRNA 286 280 208 17.8 17.18 13.35 19.25 19.81 17.77 16.11 18.94333333 347 353 317 258 339 0.018366995 0.387632295 GO:0000931///gamma-tubulin large complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0008274///gamma-tubulin ring complex GO:0003674///molecular_function GO:0008150///biological_process 72084 72084 'Pigx' mRNA 621 661 612 40.33 42.43 42.14 42.8 38.66 40.12 41.63333333 40.52666667 756 666 685 631.3333333 702.3333333 0.230399154 0.141528703 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006506///GPI anchor biosynthetic process 72085 72085 'Osgepl1' mRNA 315 300 329 9.54 8.92 10.65 7.63 7.76 9.19 9.703333333 8.193333333 290 293 340 314.6666667 307.6666667 0.836893473 -0.045966272 GO:0000408///EKC/KEOPS complex+++GO:0005739///mitochondrion "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0046872///metal ion binding+++GO:0061711///N(6)-L-threonylcarbamoyladenine synthase activity" GO:0002949///tRNA threonylcarbamoyladenosine modification+++GO:0008033///tRNA processing 72088 72088 'Ush1c' mRNA 13192 13056 12472 339.91 329.83 344.94 108.99 117.1 114.93 338.2266667 113.6733333 4645 4856 4730 12906.66667 4743.666667 6.57E-163 -1.454994307 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0002142///stereocilia ankle link complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0005903///brush border+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0032426///stereocilium tip+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0045202///synapse+++GO:1990435///upper tip-link density GO:0005515///protein binding+++GO:0030507///spectrin binding+++GO:0032029///myosin tail binding+++GO:0051015///actin filament binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007605///sensory perception of sound+++GO:0030046///parallel actin filament bundle assembly+++GO:0030154///cell differentiation+++GO:0032532///regulation of microvillus length+++GO:0034622///cellular protein-containing complex assembly+++GO:0042472///inner ear morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0046549///retinal cone cell development+++GO:0050885///neuromuscular process controlling balance+++GO:0050953///sensory perception of light stimulus+++GO:0050957///equilibrioception+++GO:0051017///actin filament bundle assembly+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:1904106///protein localization to microvillus+++GO:1904970///brush border assembly 72090 72090 'Entpd8' mRNA 213 176 178 6.49 4.88 6.01 4.01 4.12 4.29 5.793333333 4.14 149 157 131 189 145.6666667 0.070312217 -0.386572799 00230///Purine metabolism+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0045134///uridine-diphosphatase activity+++GO:0046872///metal ion binding+++GO:0102485///dATP phosphohydrolase activity+++GO:0102486///dCTP phosphohydrolase activity+++GO:0102487///dUTP phosphohydrolase activity+++GO:0102488///dTTP phosphohydrolase activity+++GO:0102489///GTP phosphohydrolase activity+++GO:0102490///8-oxo-dGTP phosphohydrolase activity+++GO:0102491///dGTP phosphohydrolase activity GO:0009124///nucleoside monophosphate biosynthetic process+++GO:0009133///nucleoside diphosphate biosynthetic process+++GO:0009134///nucleoside diphosphate catabolic process 72096 72096 'Eef1akmt2' mRNA 395 443 417 23.69 26.01 26.29 22.3 21.7 18.6 25.33 20.86666667 429 403 345 418.3333333 392.3333333 0.536113287 -0.105353249 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity GO:0018022///peptidyl-lysine methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0032259///methylation 72097 72097 'Cracdl' mRNA 2541 2617 1958 30.04 30.22 24.47 4.18 4.59 4.66 28.24333333 4.476666667 408 437 437 2372 427.3333333 2.96E-141 -2.478024062 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72098 72098 'Tmem68' mRNA 503 514 550 10.84 11.07 12.67 12.37 11.96 13.21 11.52666667 12.51333333 652 613 679 522.3333333 648 0.015395774 0.296744019 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003674///molecular_function+++GO:0016746///transferase activity, transferring acyl groups" GO:0008150///biological_process 72102 72102 'Dusp11' mRNA 1441 1466 1482 11.88 11.91 12.95 12.49 11.79 11.95 12.24666667 12.07666667 1743 1609 1616 1463 1656 0.052554774 0.165226125 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0045171///intercellular bridge "GO:0003723///RNA binding+++GO:0004651///polynucleotide 5'-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides" GO:0006470///protein dephosphorylation+++GO:0016070///RNA metabolic process+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0098507///polynucleotide 5' dephosphorylation 72103 72103 'Aplf' mRNA 295.71 256.16 206.7 5.5 4.49 4.72 5.3 5.32 5.37 4.903333333 5.33 259.49 238.14 296.06 252.8566667 264.5633333 0.805222817 0.05998389 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0035861///site of double-strand break GO:0000166///nucleotide binding+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0000012///single strand break repair+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045191///regulation of isotype switching+++GO:0051106///positive regulation of DNA ligation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 72106 72106 'Jmjd8' mRNA 2707.8 3004.39 2601.56 73.34 80.16 74.75 54.26 53.86 56.55 76.08333333 54.89 2303.56 2232.32 2323.74 2771.25 2286.54 2.52E-05 -0.287553103 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003674///molecular_function GO:0006110///regulation of glycolytic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:1903302///regulation of pyruvate kinase activity+++GO:1903672///positive regulation of sprouting angiogenesis 72107 72107 'Dscc1' mRNA 0 12 3 0 0.53 0.15 1.45 1.4 1.64 0.226666667 1.496666667 38 36 45 5 39.66666667 2.42E-05 2.989166194 "GO:0000775///chromosome, centromeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031390///Ctf18 RFC-like complex" GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity GO:0006260///DNA replication+++GO:0006275///regulation of DNA replication+++GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0032508///DNA duplex unwinding+++GO:0034088///maintenance of mitotic sister chromatid cohesion+++GO:0034421///post-translational protein acetylation+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 72108 72108 'Ddhd2' mRNA 1699 1534 1578 21.82 19.32 21.38 16.93 15.54 17.14 20.84 16.53666667 1516 1367 1494 1603.666667 1459 0.09880183 -0.149388293 GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0034451///centriolar satellite GO:0004620///phospholipase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006629///lipid metabolic process+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0034389///lipid droplet organization+++GO:0090141///positive regulation of mitochondrial fission 72112 72112 'Ppp1r14d' mRNA 54 43 48 4.72 3.73 4.55 1.26 1.82 1.36 4.333333333 1.48 15 22 18 48.33333333 18.33333333 0.001654659 -1.409032072 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity GO:0042325///regulation of phosphorylation+++GO:1905183///negative regulation of protein serine/threonine phosphatase activity+++GO:1905184///positive regulation of protein serine/threonine phosphatase activity 72113 72113 'Adck1' mRNA 711 667 619 17.2 16.75 16.09 11.64 12.86 11.19 16.68 11.89666667 548 596 512 665.6666667 552 0.01914987 -0.27985129 GO:0005576///extracellular region+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0032592///integral component of mitochondrial membrane GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007005///mitochondrion organization+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016310///phosphorylation+++GO:0055088///lipid homeostasis+++GO:1903852///positive regulation of cristae formation 72114 72114 'Zbed3' mRNA 747 717 631 16.46 16.13 15.13 11.62 12.01 11.72 15.90666667 11.78333333 614 570 586 698.3333333 590 0.0218527 -0.253105196 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001933///negative regulation of protein phosphorylation+++GO:0007015///actin filament organization+++GO:0009749///response to glucose+++GO:0016055///Wnt signaling pathway+++GO:0032868///response to insulin+++GO:0040019///positive regulation of embryonic development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050821///protein stabilization+++GO:0051293///establishment of spindle localization+++GO:0051643///endoplasmic reticulum localization+++GO:0051646///mitochondrion localization+++GO:0090263///positive regulation of canonical Wnt signaling pathway 72117 72117 'Naa50' mRNA 1305 1477 1315 15.25 17 16.29 24.72 23.71 23.54 16.18 23.99 2432 2279 2244 1365.666667 2318.333333 1.99E-24 0.75208265 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031415///NatA complex "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0052858///peptidyl-lysine acetyltransferase activity" "GO:0006474///N-terminal protein amino acid acetylation+++GO:0007064///mitotic sister chromatid cohesion+++GO:0016573///histone acetylation+++GO:0034087///establishment of mitotic sister chromatid cohesion+++GO:0043967///histone H4 acetylation+++GO:0071962///mitotic sister chromatid cohesion, centromeric" 72119 72119 'Tpx2' mRNA 52 43 45.85 0.81 0.74 0.72 6.61 5.55 6.22 0.756666667 6.126666667 475 398 416 46.95 429.6666667 2.86E-61 3.190016279 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005818///aster+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005880///nuclear microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0043203///axon hillock+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0030295///protein kinase activator activity+++GO:0061676///importin-alpha family protein binding GO:0006915///apoptotic process+++GO:0007020///microtubule nucleation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0032147///activation of protein kinase activity+++GO:0051225///spindle assembly+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:0090307///mitotic spindle assembly 72121 72121 'Dennd2d' mRNA 457.72 518.29 421.89 9.78 10.2 9.74 11.32 9.64 8.25 9.906666667 9.736666667 543.97 471.38 382.59 465.9666667 465.98 0.958547891 -0.010612765 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 72123 72123 'Ccdc71l' mRNA 92 119 102 1.19 1.52 1.4 1.67 1.98 1.55 1.37 1.733333333 148 172 133 104.3333333 151 0.031693127 0.523494543 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72124 72124 'Seh1l' mRNA 1046 1189 1202 18.18 19.71 21.48 17.94 19.6 19.17 19.79 18.90333333 1207 1248 1221 1145.666667 1225.333333 0.480873433 0.083516938 03013///Nucleocytoplasmic transport+++04150///mTOR signaling pathway+++05014///Amyotrophic lateral sclerosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005694///chromosome+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0031080///nuclear pore outer ring+++GO:0035859///Seh1-associated complex+++GO:0061700///GATOR2 complex" GO:0005198///structural molecule activity GO:0002534///cytokine production involved in inflammatory response+++GO:0006999///nuclear pore organization+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007080///mitotic metaphase plate congression+++GO:0015031///protein transport+++GO:0031503///protein-containing complex localization+++GO:0032008///positive regulation of TOR signaling+++GO:0034198///cellular response to amino acid starvation+++GO:0034629///cellular protein-containing complex localization+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051028///mRNA transport+++GO:0051301///cell division+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:1904263///positive regulation of TORC1 signaling 72125 72125 'Amer2' mRNA 1228 1229 910 6.21 6.13 4.89 1.54 2.09 2.07 5.743333333 1.9 345 461 456 1122.333333 420.6666667 6.37E-27 -1.418622368 GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008013///beta-catenin binding+++GO:0008289///lipid binding" GO:0007398///ectoderm development+++GO:0016055///Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway 72128 72128 '2610008E11Rik' mRNA 873 904 825 11.15 11.35 11.17 6.48 7.15 6.55 11.22333333 6.726666667 584 630 572 867.3333333 595.3333333 4.62E-08 -0.553030045 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72129 72129 'Pex13' mRNA 886 896 873 14.82 14.74 15.49 14.33 15.8 14.95 15.01666667 15.02666667 986 1062 996 885 1014.666667 0.064972172 0.186002829 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990429///peroxisomal importomer complex GO:0000268///peroxisome targeting sequence binding "GO:0001561///fatty acid alpha-oxidation+++GO:0001764///neuron migration+++GO:0001967///suckling behavior+++GO:0007626///locomotory behavior+++GO:0015031///protein transport+++GO:0016560///protein import into peroxisome matrix, docking+++GO:0021795///cerebral cortex cell migration+++GO:0060152///microtubule-based peroxisome localization" 72133 72133 'Trub1' mRNA 466.53 469.58 447.82 6.28 6.24 6.29 3.68 3.75 3.65 6.27 3.693333333 315.46 312.45 305.23 461.31 311.0466667 7.05E-06 -0.579821495 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity GO:0001522///pseudouridine synthesis+++GO:0006396///RNA processing+++GO:0006400///tRNA modification+++GO:0009451///RNA modification+++GO:1990481///mRNA pseudouridine synthesis 72135 72135 'Pygo1' mRNA 853 897 635 5.39 5.57 4.25 1.1 1.26 1.09 5.07 1.15 201 224 193 795 206 9.38E-46 -1.952748026 GO:0005634///nucleus GO:0005515///protein binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding GO:0001822///kidney development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007286///spermatid development+++GO:0007289///spermatid nucleus differentiation+++GO:0016055///Wnt signaling pathway+++GO:0034504///protein localization to nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048856///anatomical structure development+++GO:0060070///canonical Wnt signaling pathway 72136 72136 'Chst14' mRNA 333 294 169 9.03 7.86 4.86 9.3 12.25 11.99 7.25 11.18 394 507 492 265.3333333 464.3333333 4.14E-05 0.809713137 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001537///N-acetylgalactosamine 4-O-sulfotransferase activity+++GO:0005515///protein binding+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0016051///carbohydrate biosynthetic process+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0050655///dermatan sulfate proteoglycan metabolic process 72137 72137 'Wdsub1' mRNA 1608.12 1581.13 1530.67 44.2 42.21 43.67 22.92 21.77 21.25 43.36 21.98 973.36 906 862 1573.306667 913.7866667 1.72E-22 -0.796071177 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0004842///ubiquitin-protein transferase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination 72139 72139 '2610044O15Rik8' mRNA 355.01 402.19 372 11.54 12.89 12.83 8.95 8.69 7.99 12.42 8.543333333 316.28 300.05 273.37 376.4 296.5666667 0.016585311 -0.357012303 GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72140 72140 'Cep89' mRNA 778 753 701 11.3 10.77 10.81 6.77 7.07 6.26 10.96 6.7 536 546 480 744 520.6666667 1.27E-06 -0.525553289 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0031514///motile cilium+++GO:0045202///synapse+++GO:0097539///ciliary transition fiber+++GO:0097730///non-motile cilium GO:0005515///protein binding GO:0007005///mitochondrion organization+++GO:0007268///chemical synaptic transmission+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:1905515///non-motile cilium assembly 72141 72141 'Adpgk' mRNA 623 573 591 14.07 12.74 14.16 17.36 18.64 16.84 13.65666667 17.61333333 884 927 830 595.6666667 880.3333333 1.67E-07 0.551554229 00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum "GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0043843///ADP-specific glucokinase activity+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006096///glycolytic process+++GO:0016310///phosphorylation 72144 72144 'Slc37a3' mRNA 1719.15 1731.11 1616.43 22.44 22.26 22.42 16.13 16.58 16.29 22.37333333 16.33333333 1420.82 1433.83 1395.56 1688.896667 1416.736667 4.88E-04 -0.264927656 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0022857///transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0055085///transmembrane transport 72145 72145 'Wdfy3' mRNA 2487.59 2614.43 2412.83 8.55 8.91 9 8.66 8.05 8.09 8.82 8.266666667 2927.88 2651.47 2628.42 2504.95 2735.923333 0.115283848 0.115294344 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016234///inclusion body+++GO:0016605///PML body+++GO:0019898///extrinsic component of membrane+++GO:0030424///axon+++GO:0034274///Atg12-Atg5-Atg16 complex+++GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0097635///extrinsic component of autophagosome membrane "GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0005545///1-phosphatidylinositol binding+++GO:0008289///lipid binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" GO:0006914///autophagy+++GO:0007275///multicellular organism development+++GO:0035973///aggrephagy 72147 72147 'Zbtb46' mRNA 277.2 329 268 3.8 4.31 4.13 3.95 4.6 3.54 4.08 4.03 322.15 329 278.04 291.4 309.73 0.703304273 0.078707867 GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0045650///negative regulation of macrophage differentiation+++GO:0045656///negative regulation of monocyte differentiation+++GO:2001199///negative regulation of dendritic cell differentiation+++GO:2001200///positive regulation of dendritic cell differentiation 72148 72148 'Tdrp' mRNA 1066 1047 1050 24.13 23.32 25.2 25.98 24.84 24.43 24.21666667 25.08333333 1320 1234 1205 1054.333333 1253 0.008131098 0.236126667 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0008150///biological_process 72149 72149 'Strada' mRNA 299 366 308 7.9 9.23 8.42 13.03 11.44 12.49 8.516666667 12.32 575 493 535 324.3333333 534.3333333 6.17E-08 0.708891244 04150///mTOR signaling pathway+++04152///AMPK signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019900///kinase binding+++GO:0030295///protein kinase activator activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0044877///protein-containing complex binding GO:0006468///protein phosphorylation+++GO:0006611///protein export from nucleus+++GO:0007049///cell cycle+++GO:0032147///activation of protein kinase activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity 72151 72151 'Rfc5' mRNA 311 280 263 10.41 9.24 9.34 15.73 15.73 15.54 9.663333333 15.66666667 540 527 516 284.6666667 527.6666667 4.29E-12 0.879909313 03030///DNA replication+++03420///Nucleotide excision repair+++03430///Mismatch repair GO:0005634///nucleus+++GO:0005663///DNA replication factor C complex+++GO:0031390///Ctf18 RFC-like complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003689///DNA clamp loader activity+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0019899///enzyme binding GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0032508///DNA duplex unwinding+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity 72154 72154 'Zfp157' mRNA 719.32 754 708.53 4.61 5.09 4.91 3.37 2.61 3.13 4.87 3.036666667 586 455.34 545 727.2833333 528.78 4.96E-05 -0.472867982 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010453///regulation of cell fate commitment+++GO:0048286///lung alveolus development+++GO:0060443///mammary gland morphogenesis" 72155 72155 'Cenpn' mRNA 27 19 11 0.91 0.68 0.38 3.55 3.03 3.15 0.656666667 3.243333333 124 104 104 19 110.6666667 6.73E-13 2.536620732 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome" GO:0003674///molecular_function GO:0007059///chromosome segregation+++GO:0051382///kinetochore assembly 72157 72157 'Pgm1' mRNA 1934 1904 2108 46.44 45.03 53.71 41.01 42.71 40.58 48.39333333 41.43333333 1964 1997 1881 1982 1947.333333 0.736130456 -0.040293066 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00052///Galactose metabolism+++00230///Purine metabolism+++00500///Starch and sucrose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030018///Z disc "GO:0000287///magnesium ion binding+++GO:0004614///phosphoglucomutase activity+++GO:0008973///phosphopentomutase activity+++GO:0016853///isomerase activity+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0046386///deoxyribose phosphate catabolic process+++GO:0071704///organic substance metabolic process 72160 72160 'Tmem163' mRNA 0 4 4 0 0.09 0.09 0.04 0 0.02 0.06 0.02 2 0 1 2.666666667 1 0.559452592 -1.453308433 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0045202///synapse+++GO:0097708///intracellular vesicle GO:0005515///protein binding+++GO:0008270///zinc ion binding GO:0099180///zinc ion import into synaptic vesicle 72162 72162 'Dhx36' mRNA 716 708 629 7.07 6.84 6.53 6.82 5.99 6.57 6.813333333 6.46 791 670 729 684.3333333 730 0.521702756 0.082127485 03018///RNA degradation "GO:0000781///chromosome, telomeric region+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043204///perikaryon" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0002151///G-quadruplex RNA binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0051880///G-quadruplex DNA binding+++GO:0070034///telomerase RNA binding+++GO:0070883///pre-miRNA binding "GO:0001503///ossification+++GO:0002376///immune system process+++GO:0002735///positive regulation of myeloid dendritic cell cytokine production+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009615///response to virus+++GO:0010501///RNA secondary structure unwinding+++GO:0010628///positive regulation of gene expression+++GO:0017148///negative regulation of translation+++GO:0030154///cell differentiation+++GO:0031442///positive regulation of mRNA 3'-end processing+++GO:0032206///positive regulation of telomere maintenance+++GO:0032508///DNA duplex unwinding+++GO:0032727///positive regulation of interferon-alpha production+++GO:0034605///cellular response to heat+++GO:0034644///cellular response to UV+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043330///response to exogenous dsRNA+++GO:0043488///regulation of mRNA stability+++GO:0044806///G-quadruplex DNA unwinding+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045995///regulation of embryonic development+++GO:0051607///defense response to virus+++GO:0051891///positive regulation of cardioblast differentiation+++GO:0060261///positive regulation of transcription initiation from RNA polymerase II promoter+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0090669///telomerase RNA stabilization+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:1901534///positive regulation of hematopoietic progenitor cell differentiation+++GO:1902064///regulation of transcription from RNA polymerase II promoter involved in spermatogenesis+++GO:1903843///cellular response to arsenite ion+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:1904582///positive regulation of intracellular mRNA localization+++GO:2000767///positive regulation of cytoplasmic translation" 72167 72167 'Thumpd2' mRNA 201.19 218.86 223.19 5.14 5.57 5.97 4.75 5.36 5.48 5.56 5.196666667 213.91 224.15 220.99 214.4133333 219.6833333 0.930264028 0.020414563 GO:0005575///cellular_component GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0016740///transferase activity GO:0030488///tRNA methylation+++GO:0032259///methylation 72168 72168 'Aifm3' mRNA 284 332 209 5.42 6.3 4.15 2.41 2.26 2.31 5.29 2.326666667 148 134 134 275 138.6666667 2.81E-07 -0.992295397 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol "GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0046872///metal ion binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" GO:0006915///apoptotic process+++GO:0097194///execution phase of apoptosis 72169 72169 'Trim29' mRNA 0 2 3 0 0.04 0.06 0.1 0.12 0.05 0.033333333 0.09 6 7 3 1.666666667 5.333333333 0.306270993 1.649803862 GO:0005737///cytoplasm+++GO:0005764///lysosome GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:1900181///negative regulation of protein localization to nucleus 72170 72170 'Chchd4' mRNA 598 495 497 29.29 23.94 25.83 27.27 27.17 26.65 26.35333333 27.03 639 621 604 530 621.3333333 0.086549257 0.21822343 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity GO:0015031///protein transport+++GO:0018171///peptidyl-cysteine oxidation+++GO:0022417///protein maturation by protein folding+++GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0034599///cellular response to oxidative stress+++GO:0043504///mitochondrial DNA repair+++GO:0045041///protein import into mitochondrial intermembrane space+++GO:0046825///regulation of protein export from nucleus+++GO:0051084///'de novo' posttranslational protein folding+++GO:0072655///establishment of protein localization to mitochondrion+++GO:1901857///positive regulation of cellular respiration+++GO:1990830///cellular response to leukemia inhibitory factor 72171 72171 'Shq1' mRNA 146 185 201 3.62 4.96 5.5 4.29 4.35 3.41 4.693333333 4.016666667 189 187 160 177.3333333 178.6666667 0.990872898 -0.005605814 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0051082///unfolded protein binding GO:0000493///box H/ACA snoRNP assembly+++GO:0022618///ribonucleoprotein complex assembly+++GO:0043065///positive regulation of apoptotic process+++GO:2000233///negative regulation of rRNA processing 72175 72175 'Mfsd8' mRNA 255 280 280 4.53 4.78 5.15 3.52 3.91 4.7 4.82 4.043333333 234 250 302 271.6666667 262 0.782036762 -0.06436142 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0007040///lysosome organization+++GO:0010506///regulation of autophagy+++GO:0038202///TORC1 signaling+++GO:0048666///neuron development+++GO:0055085///transmembrane transport+++GO:0097352///autophagosome maturation+++GO:1905165///regulation of lysosomal protein catabolic process 72179 72179 'Fbxl2' mRNA 199.97 211.97 183.96 3.35 3.64 4.36 2.5 2.32 2.99 3.783333333 2.603333333 165.63 152.64 197.81 198.6333333 172.0266667 0.326025435 -0.216165912 GO:0016020///membrane+++GO:0019005///SCF ubiquitin ligase complex GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0019903///protein phosphatase binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0010506///regulation of autophagy+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0044830///modulation by host of viral RNA genome replication 72180 72180 'Zfp661' mRNA 272 241 229 4.39 3.65 3.86 2.48 2.13 2.83 3.966666667 2.48 188 150 196 247.3333333 178 0.009485914 -0.486190792 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72181 72181 'Nsun4' mRNA 411 455 464 10.26 11.26 12.37 10.77 11.39 11.53 11.29666667 11.23 493 508 510 443.3333333 503.6666667 0.23270221 0.170877335 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0009383///rRNA (cytosine-C5-)-methyltransferase activity+++GO:0016428///tRNA (cytosine-5-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0019843///rRNA binding+++GO:0070181///small ribosomal subunit rRNA binding GO:0001510///RNA methylation+++GO:0006364///rRNA processing+++GO:0030488///tRNA methylation+++GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0070131///positive regulation of mitochondrial translation 72183 72183 'Snx6' mRNA 1490 1498 1598 45.24 44.76 51.44 79.2 81.09 78.08 47.14666667 79.45666667 3001 2997 2862 1528.666667 2953.333333 3.53E-34 0.93603068 04144///Endocytosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0097422///tubular endosome GO:0008289///lipid binding+++GO:0034452///dynactin binding+++GO:0034713///type I transforming growth factor beta receptor binding+++GO:0035091///phosphatidylinositol binding+++GO:0042803///protein homodimerization activity "GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1904646///cellular response to amyloid-beta" 72184 72184 'Klhl35' mRNA 71.3 65.18 61.76 1.01 0.85 0.77 0.3 0.38 0.42 0.876666667 0.366666667 32.01 37.26 43.4 66.08 37.55666667 0.022368539 -0.823688807 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72185 72185 'Dbndd1' mRNA 385 399 413 7.64 7.81 8.94 1.11 0.94 1.25 8.13 1.1 51 46 61 399 52.66666667 5.49E-52 -2.935328693 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006469///negative regulation of protein kinase activity 72190 72190 '2510009E07Rik' mRNA 1166 1244 777 12.05 12.64 8.52 8.53 8.62 10.11 11.07 9.086666667 951 938 1091 1062.333333 993.3333333 0.542865306 -0.098868249 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007399///nervous system development+++GO:0048512///circadian behavior 72193 72193 'Scaf11' mRNA 2516.02 2625.4 2015.97 17.08 17.5 14.54 11.85 12.58 12.65 16.37333333 12.36 2015.13 2088 2074.54 2385.796667 2059.223333 0.010470891 -0.218509954 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0008380///RNA splicing" 72194 72194 'Fbxl20' mRNA 909 874 551 5.5 5.17 3.55 3.37 4.63 4.26 4.74 4.086666667 640 859 783 778 760.6666667 0.876147748 -0.031381968 GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding "GO:0001662///behavioral fear response+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0099575///regulation of protein catabolic process at presynapse, modulating synaptic transmission+++GO:2000300///regulation of synaptic vesicle exocytosis" 72195 72195 'Supt7l' mRNA 610.05 583.94 622.49 12.62 11.9 13.67 10.67 10.19 10.2 12.73 10.35333333 593.28 553.06 548.95 605.4933333 565.0966667 0.398939066 -0.113559256 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0046982///protein heterodimerization activity "GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051457///maintenance of protein location in nucleus" 72198 72198 'Mtrex' mRNA 995 967 989.23 16.33 15.68 17.26 13.1 12.79 12.1 16.42333333 12.66333333 918.15 879.01 823.42 983.7433333 873.5266667 0.070932699 -0.184814042 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0031499///TRAMP complex+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0000460///maturation of 5.8S rRNA+++GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0006401///RNA catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008380///RNA splicing 72199 72199 'Mms19' mRNA 1042.87 1106.03 1028.05 16.33 16.85 17.07 15.49 14.22 15.15 16.75 14.95333333 1144.75 1030.77 1083.23 1058.983333 1086.25 0.850261782 0.024267985 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0071817///MMXD complex+++GO:0097361///CIA complex GO:0003713///transcription coactivator activity+++GO:0019899///enzyme binding+++GO:0030331///estrogen receptor binding "GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007059///chromosome segregation+++GO:0016226///iron-sulfur cluster assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:1905168///positive regulation of double-strand break repair via homologous recombination" 72201 72201 'Otud6b' mRNA 936 1030 861 16.61 17.97 16.17 20.09 19.62 19.28 16.91666667 19.66333333 1302 1242 1211 942.3333333 1251.666667 4.27E-06 0.399833013 GO:0016281///eukaryotic translation initiation factor 4F complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0008283///cell proliferation+++GO:0016579///protein deubiquitination+++GO:0017148///negative regulation of translation+++GO:0043248///proteasome assembly+++GO:0045727///positive regulation of translation 72205 72205 'Eml2' mRNA 183 118 75 4.51 2.88 1.96 3.68 2.82 3.87 3.116666667 3.456666667 170 127 174 125.3333333 157 0.317013117 0.322846267 GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0072686///mitotic spindle GO:0005102///signaling receptor binding+++GO:0008017///microtubule binding+++GO:0008022///protein C-terminus binding+++GO:0015631///tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0010968///regulation of microtubule nucleation+++GO:0031115///negative regulation of microtubule polymerization 72215 72215 '1700001P01Rik' mRNA 3 1 0 0.36 0.12 0 0.42 0.22 0.44 0.16 0.36 4 2 4 1.333333333 3.333333333 0.517614811 1.327801199 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72219 72219 'Spata31d1a' mRNA 3.99 0 0 0.05 0 0 0 0 0.03 0.016666667 0.01 0 0 2.5 1.33 0.833333333 0.888377162 -0.566201992 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72230 72230 'Zfp558' mRNA 95.69 124.01 89.51 0.71 0.91 0.74 0.51 0.76 0.49 0.786666667 0.586666667 76.68 93.78 73.91 103.07 81.45666667 0.244138081 -0.35382096 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 72236 72236 'Tsnaxip1' mRNA 38 61 43 0.97 1.52 1.16 0.18 0.3 0.23 1.216666667 0.236666667 8 13 10 47.33333333 10.33333333 1.45E-05 -2.200913756 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 72238 72238 'Tbc1d5' mRNA 497 539 463 4.93 5.1 4.72 4.58 4.21 4.6 4.916666667 4.463333333 556 493 539 499.6666667 529.3333333 0.626361703 0.072610988 GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030904///retromer complex+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990316///Atg1/ULK1 kinase complex GO:0005096///GTPase activator activity+++GO:0035612///AP-2 adaptor complex binding+++GO:0044877///protein-containing complex binding+++GO:1905394///retromer complex binding "GO:0002092///positive regulation of receptor internalization+++GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0042594///response to starvation+++GO:0090630///activation of GTPase activity" 72240 72240 '1600014C23Rik' mRNA 12 10 3 1.92 1.6 0.51 0.2 0.2 0 1.343333333 0.133333333 1 1 0 8.333333333 0.666666667 0.023890395 -3.635982382 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72242 72242 'Psg21' mRNA 6 2.22 2.36 0.16 0.06 0.07 0.05 0 0 0.096666667 0.016666667 2 0 0 3.526666667 0.666666667 0.30336365 -2.342233984 GO:0005575///cellular_component GO:0003674///molecular_function GO:0006909///phagocytosis+++GO:0007565///female pregnancy+++GO:0008150///biological_process 72244 72244 '1600014C10Rik' mRNA 406 429 376 7.01 7.27 6.88 21.18 22 21.82 7.053333333 21.66666667 1419 1440 1425 403.6666667 1428 2.49E-87 1.812895253 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0006979///response to oxidative stress+++GO:0051560///mitochondrial calcium ion homeostasis 72254 72254 '1700030K09Rik' mRNA 429 392 404 9.79 8.85 9.84 5.88 5.78 5.02 9.493333333 5.56 295 282 243 408.3333333 273.3333333 4.88E-05 -0.59203794 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72265 72265 'Tram1' mRNA 3118 3312 1437 58.28 60.92 28.49 44.61 63.79 59.59 49.23 55.99666667 2746 3835 3552 2622.333333 3377.666667 0.410893596 0.374824315 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0003674///molecular_function "GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0015031///protein transport+++GO:0045048///protein insertion into ER membrane" 72267 72267 'Lrrc8e' mRNA 289.73 275.42 299.01 4.19 4.05 4.51 2.38 2.53 2.46 4.25 2.456666667 186.26 184.69 183.49 288.0533333 184.8133333 9.06E-05 -0.655935442 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0034702///ion channel complex+++GO:1905103///integral component of lysosomal membrane GO:0005225///volume-sensitive anion channel activity GO:0006811///ion transport+++GO:0006884///cell volume homeostasis+++GO:0015698///inorganic anion transport+++GO:0015810///aspartate transmembrane transport+++GO:0071470///cellular response to osmotic stress+++GO:0098656///anion transmembrane transport 72269 72269 'Cda' mRNA 99 78 120 8.31 6.49 10.69 13.5 14.54 14.38 8.496666667 14.14 184 193 189 99 188.6666667 9.67E-05 0.911759238 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005829///cytosol GO:0001882///nucleoside binding+++GO:0003824///catalytic activity+++GO:0004126///cytidine deaminase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019239///deaminase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047844///deoxycytidine deaminase activity GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0009972///cytidine deamination+++GO:0030308///negative regulation of cell growth+++GO:0044206///UMP salvage+++GO:0045980///negative regulation of nucleotide metabolic process 72273 72273 'Smim24' mRNA 6 11 12 0.82 1.49 1.73 3.93 5.27 4.7 1.346666667 4.633333333 33 43 38 9.666666667 38 3.75E-04 1.961064326 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72275 72275 '2200002D01Rik' mRNA 11 19 29 1.82 3.15 5.1 15.3 12.46 19.68 3.356666667 15.81333333 105 83 130 19.66666667 106 3.56E-10 2.407141921 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 72277 72277 'Fam186a' mRNA 8 5 14 0.05 0.03 0.08 0.01 0.01 0 0.053333333 0.006666667 3 1 0 9 1.333333333 0.039962663 -2.796595803 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72278 72278 'Ccpg1' mRNA 4305.55 4788.93 4285.59 79.33 86.8 83.56 59.97 56.07 59.48 83.23 58.50666667 3768.85 3439.96 3601.09 4460.023333 3603.3 3.26E-07 -0.319313518 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001106///regulation of Rho guanyl-nucleotide exchange factor activity 72281 72281 'Sh2d4a' mRNA 139 184 178 2.78 3.76 3.8 2.67 2.97 2.81 3.446666667 2.816666667 152 165 152 167 156.3333333 0.696837118 -0.108273911 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0019902///phosphatase binding GO:0010923///negative regulation of phosphatase activity 72282 72282 '1810062G17Rik' mRNA 30 38 29 2.16 2.7 2.21 1.13 0.71 0.97 2.356666667 0.936666667 18 11 15 32.33333333 14.66666667 0.033206589 -1.151854055 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72284 72284 'LTO1' mRNA 700.06 756.17 685.5 18.69 19.85 19.45 19.09 19.33 21.39 19.33 19.93666667 808.87 808.18 885.24 713.91 834.0966667 0.046311407 0.213654118 GO:0005634///nucleus GO:0003674///molecular_function GO:0000723///telomere maintenance+++GO:0006413///translational initiation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer 72287 72287 'Plekhf1' mRNA 637 603 577 24.01 22.31 23.03 29.01 29.58 27.87 23.11666667 28.82 886 880 823 605.6666667 863 5.92E-07 0.49974455 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0048471///perinuclear region of cytoplasm GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0046872///metal ion binding+++GO:0070273///phosphatidylinositol-4-phosphate binding GO:0006915///apoptotic process+++GO:0007032///endosome organization+++GO:0010508///positive regulation of autophagy+++GO:0016050///vesicle organization+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0072659///protein localization to plasma membrane+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 72290 72290 'Lsm11' mRNA 117 118.96 76 0.96 0.96 0.66 0.48 0.36 0.51 0.86 0.45 67 49 70 103.9866667 62 0.013895366 -0.746863082 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005683///U7 snRNP+++GO:0005697///telomerase holoenzyme complex+++GO:0016604///nuclear body+++GO:0071204///histone pre-mRNA 3'end processing complex GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0071209///U7 snRNA binding GO:0006397///mRNA processing+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 72293 72293 'Nkd2' mRNA 117 107 94 1.57 1.41 1.35 1.09 1.13 1.3 1.443333333 1.173333333 93 94 108 106 98.33333333 0.725652483 -0.116959769 04310///Wnt signaling pathway+++04390///Hippo signaling pathway GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0070382///exocytic vesicle+++GO:0071944///cell periphery GO:0005509///calcium ion binding+++GO:0019838///growth factor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0032036///myosin heavy chain binding+++GO:0046872///metal ion binding+++GO:0051117///ATPase binding GO:0006887///exocytosis+++GO:0010954///positive regulation of protein processing+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0048210///Golgi vesicle fusion to target membrane+++GO:0072659///protein localization to plasma membrane+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1903078///positive regulation of protein localization to plasma membrane 72296 72296 'Rusc1' mRNA 478 578 510 13.36 16.32 15.21 12.96 12.66 12.86 14.96333333 12.82666667 537 506 516 522 519.6666667 0.909182921 -0.017970441 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse GO:0003779///actin binding GO:0000209///protein polyubiquitination 72297 72297 'B3gnt3' mRNA 11 16 14 0.3 0.37 0.36 3.43 3.05 3.51 0.343333333 3.33 165 140 165 13.66666667 156.6666667 4.94E-26 3.506672569 00512///Mucin type O-glycan biosynthesis+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008457///beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0047223///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 72301 72301 'Shisal1' mRNA 750 685 608 6.75 6.01 5.82 0.6 0.43 0.47 6.193333333 0.5 76 54 61 681 63.66666667 2.01E-96 -3.429658688 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72303 72303 'Cyp2c65' mRNA 4 1 1 0.12 0.03 0.03 0 0 0 0.06 0 0 0 0 2 0 0.256867881 -3.442125442 00140///Steroid hormone biosynthesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++00830///Retinol metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++05204///Chemical carcinogenesis - DNA adducts GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008390///testosterone 16-alpha-hydroxylase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008401///retinoic acid 4-hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0019899///enzyme binding+++GO:0020037///heme binding+++GO:0034875///caffeine oxidase activity+++GO:0046872///metal ion binding+++GO:0101020///estrogen 16-alpha-hydroxylase activity" GO:0006082///organic acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process 72306 72306 'Zfp777' mRNA 197 185 190 3.05 3.08 3.18 2.64 2.55 2.31 3.103333333 2.5 192 172 156 190.6666667 173.3333333 0.511763027 -0.150987909 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 72307 72307 '2510002D24Rik' mRNA 1262.96 1301.56 1175.63 50.78 52.27 48.98 34.61 32.98 31.72 50.67666667 33.10333333 913.21 857.92 817.95 1246.716667 863.0266667 2.22E-10 -0.542016995 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72308 72308 'Brf1' mRNA 1222 1170 815.33 15.23 13.6 10.41 7.4 9.72 9.24 13.08 8.786666667 677 854 792 1069.11 774.3333333 5.71E-04 -0.466830424 GO:0000126///transcription factor TFIIIB complex+++GO:0005634///nucleus+++GO:0097550///transcriptional preinitiation complex GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0017025///TBP-class protein binding+++GO:0046872///metal ion binding "GO:0006352///DNA-templated transcription, initiation+++GO:0006383///transcription by RNA polymerase III+++GO:0043488///regulation of mRNA stability+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0070897///transcription preinitiation complex assembly" 72309 72309 'Tmem158' mRNA 49 58 5 1.64 1.91 0.18 0.9 0.95 1.74 1.243333333 1.196666667 31 32 58 37.33333333 40.33333333 0.863090843 0.133074708 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0042277///peptide binding GO:0008150///biological_process 72310 72310 'Nkg7' mRNA 17 19 13 1.42 1.57 1.15 10.05 8.08 9.2 1.38 9.11 138 108 122 16.33333333 122.6666667 1.18E-17 2.898973549 GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72313 72313 'Fryl' mRNA 4919.6 4640.41 4257.64 21.82 20.22 20.09 12.89 10.66 13.53 20.71 12.36 3350 2717.54 3395.79 4605.883333 3154.443333 1.20E-12 -0.557621344 GO:0005938///cell cortex+++GO:0030427///site of polarized growth GO:0005515///protein binding GO:0000902///cell morphogenesis+++GO:0031175///neuron projection development 72315 72315 'Ccdc74a' mRNA 102 91 56 4.98 4.45 2.87 0.91 1.06 1.56 4.1 1.176666667 21 24 35 83 26.66666667 1.42E-05 -1.638145074 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72318 72318 'Cyth4' mRNA 412 385 384 8.6 7.53 8.31 51.51 53.77 50.23 8.146666667 51.83666667 2963 3025 2801 393.6666667 2929.666667 2.11E-264 2.884432422 04072///Phospholipase D signaling pathway+++04144///Endocytosis+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034451///centriolar satellite+++GO:0045171///intercellular bridge GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity 72320 72320 'Kifbp' mRNA 1154 1141 422 25.7 25 9.85 7.17 7.31 8.57 20.18333333 7.683333333 376 372 433 905.6666667 393.6666667 0.008655832 -1.192592275 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton GO:0019894///kinesin binding GO:0001701///in utero embryonic development+++GO:0006839///mitochondrial transport+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation 72322 72322 'Xpo5' mRNA 880 922 916 9.3 9.58 10.27 8.53 8.2 8.83 9.716666667 8.52 929 873 932 906 911.3333333 0.976360716 -0.004527888 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016442///RISC complex+++GO:0042565///RNA nuclear export complex GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005049///nuclear export signal receptor activity+++GO:0031267///small GTPase binding+++GO:0070883///pre-miRNA binding+++GO:1905172///RISC complex binding GO:0006405///RNA export from nucleus+++GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0031047///gene silencing by RNA+++GO:0035281///pre-miRNA export from nucleus+++GO:0051168///nuclear export+++GO:1900370///positive regulation of RNA interference 72323 72323 'Asb6' mRNA 581 662 598 15.56 17.46 16.98 21.59 19.51 19.15 16.66666667 20.08333333 927 818 796 613.6666667 847 2.17E-05 0.452555227 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 72324 72324 'Plxdc1' mRNA 32.77 29.64 39.41 0.62 0.54 0.79 2.14 2.06 2.1 0.65 2.1 129.44 123.04 123.79 33.94 125.4233333 9.19E-11 1.890638763 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex GO:0005515///protein binding GO:0001525///angiogenesis+++GO:0021510///spinal cord development 72325 72325 'Vps9d1' mRNA 1096 1023 985 21.4 19.66 20.42 11.83 11.54 11.49 20.49333333 11.62 697 664 655 1034.666667 672 8.08E-12 -0.634063485 GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding GO:0008150///biological_process+++GO:0016192///vesicle-mediated transport+++GO:0050790///regulation of catalytic activity 72330 72330 'Klhl40' mRNA 93 75 78 2.11 1.68 1.88 1.6 1.25 1.71 1.89 1.52 81 62 84 82 75.66666667 0.739687458 -0.128904874 GO:0005737///cytoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031672///A band+++GO:0031674///I band GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0048741///skeletal muscle fiber development+++GO:0098528///skeletal muscle fiber differentiation 72333 72333 'Palld' mRNA 2443 2479 2218 26.69 26.91 25.78 42.67 40.85 39.92 26.46 41.14666667 4020 3790 3681 2380 3830.333333 4.33E-29 0.675853132 GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0030018///Z disc+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0060076///excitatory synapse GO:0003779///actin binding+++GO:0008046///axon guidance receptor activity+++GO:0008092///cytoskeletal protein binding GO:0003334///keratinocyte development+++GO:0003382///epithelial cell morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007411///axon guidance+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0031529///ruffle organization+++GO:0050808///synapse organization+++GO:0071803///positive regulation of podosome assembly 72338 72338 'Wdr89' mRNA 124.96 120.83 106.01 2.3 2.19 2.07 1.93 2.02 1.95 2.186666667 1.966666667 120.73 123.06 118.13 117.2666667 120.64 0.903550338 0.035248279 GO:0005575///cellular_component GO:0003674///molecular_function 72341 72341 'Elp6' mRNA 251 269 270 6.81 7.22 7.83 7.13 7.83 6.73 7.286666667 7.23 299 320 273 263.3333333 297.3333333 0.379089419 0.162682802 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0033588///Elongator holoenzyme complex GO:0003674///molecular_function GO:0002098///tRNA wobble uridine modification+++GO:0008033///tRNA processing+++GO:0030335///positive regulation of cell migration 72344 72344 'Usp36' mRNA 769 763 671 8.11 7.73 7.49 5.94 5.78 6.23 7.776666667 5.983333333 670 604 645 734.3333333 639.6666667 0.054333028 -0.209435146 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007000///nucleolus organization+++GO:0016242///negative regulation of macroautophagy+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability+++GO:0042981///regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:2000232///regulation of rRNA processing 72345 72345 'Amer1' mRNA 456 509 462 2.83 3.1 3.04 2.13 2.34 2.18 2.99 2.216666667 395 425 392 475.6666667 404 0.069691129 -0.246156877 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle "GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008013///beta-catenin binding+++GO:0008289///lipid binding+++GO:1904713///beta-catenin destruction complex binding" GO:0001822///kidney development+++GO:0016055///Wnt signaling pathway+++GO:0031398///positive regulation of protein ubiquitination+++GO:0060348///bone development+++GO:0060612///adipose tissue development+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0072161///mesenchymal cell differentiation involved in kidney development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1903364///positive regulation of cellular protein catabolic process 72349 72349 'Dusp3' mRNA 2352 2455 2280 40.62 42.37 42.19 64.37 70.47 63.41 41.72666667 66.08333333 4571 4745 4282 2362.333333 4532.666667 2.66E-46 0.929284118 04010///MAPK signaling pathway GO:0001772///immunological synapse+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008092///cytoskeletal protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019901///protein kinase binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0033549///MAP kinase phosphatase activity+++GO:1990782///protein tyrosine kinase binding GO:0000188///inactivation of MAPK activity+++GO:0001701///in utero embryonic development+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043409///negative regulation of MAPK cascade+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046329///negative regulation of JNK cascade+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050868///negative regulation of T cell activation+++GO:0050922///negative regulation of chemotaxis+++GO:0051893///regulation of focal adhesion assembly+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0120183///positive regulation of focal adhesion disassembly+++GO:1990264///peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity 72350 72350 'Zc2hc1c' mRNA 359 430 358 6.38 7.5 6.4 1.95 2.34 1.71 6.76 2 130 152 120 382.3333333 134 1.15E-19 -1.521466434 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 72351 72351 'Ptar1' mRNA 875 840 701 6.91 6.8 5.41 5.64 4.33 5.69 6.373333333 5.22 791 647 738 805.3333333 725.3333333 0.184140142 -0.160638106 GO:0005737///cytoplasm GO:0008318///protein prenyltransferase activity GO:0018342///protein prenylation 72354 72354 'Ttc4' mRNA 1072 1148 1129 23.26 24.5 26.03 19.42 19.76 18.83 24.59666667 19.33666667 1031 1025 969 1116.333333 1008.333333 0.108019317 -0.159523703 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0051879///Hsp90 protein binding GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0051607///defense response to virus 72355 72355 'Cdpf1' mRNA 367 419 356 23.11 26.43 24.6 26.9 23.91 25.18 24.71333333 25.33 471 406 424 380.6666667 433.6666667 0.229662578 0.17695524 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72357 72357 '2210016L21Rik' mRNA 1452 1417 1405 65.83 63.41 67.52 47.65 45.23 46.12 65.58666667 46.33333333 1209 1121 1129 1424.666667 1153 1.13E-04 -0.317913726 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005635///nuclear envelope GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0060061///Spemann organizer formation 72361 72361 'Ces2g' mRNA 103.14 101.51 75.93 1.99 1.93 1.57 0.19 0.24 0.31 1.83 0.246666667 9.37 13.42 17.96 93.52666667 13.58333333 4.74E-13 -2.842704728 00983///Drug metabolism - other enzymes GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0004771///sterol esterase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006693///prostaglandin metabolic process+++GO:0016042///lipid catabolic process 72368 72368 'Borcs8' mRNA 759.89 724 729.97 37.45 36.28 38.12 34.68 30.67 35.61 37.28333333 33.65333333 930.89 782.82 894.87 737.9533333 869.5266667 0.040269299 0.223061344 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0099078///BORC complex GO:0003674///molecular_function GO:0007507///heart development+++GO:0008150///biological_process 72371 72371 '2210408I21Rik' mRNA 1266.43 1342.28 1147.24 11.49 11.82 11.44 5.32 4.78 5.38 11.58333333 5.16 699.47 607.69 686.79 1251.983333 664.65 2.57E-24 -0.924918217 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72373 72373 'Psca' mRNA 1 1 0 0.08 0.08 0 0 0 0.14 0.053333333 0.046666667 0 0 2 0.666666667 0.666666667 0.998591786 0.025105917 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0033130///acetylcholine receptor binding GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0099601///regulation of neurotransmitter receptor activity 72383 72383 'Cnfn' mRNA 13 23 20 1.39 3.31 2.41 0.34 0.44 0.7 2.37 0.493333333 3 5 5 18.66666667 4.333333333 0.008737257 -2.117439833 GO:0001533///cornified envelope+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0031424///keratinization 72388 72388 'Ripk4' mRNA 756 713 696 11.45 10.61 11.18 7.31 7.84 7 11.08 7.383333333 556 584 517 721.6666667 552.3333333 3.50E-04 -0.396927487 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0002009///morphogenesis of an epithelium+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 72391 72391 'Cdkn3' mRNA 6 4 6 0.54 0.36 0.57 6.65 5.98 8.76 0.49 7.13 86 77 111 5.333333333 91.33333333 1.47E-16 4.085103058 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity GO:0006470///protein dephosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0051726///regulation of cell cycle 72392 72392 'Tmem175' mRNA 1012.12 1075.92 1069.19 22.02 23.43 24.27 22.12 22.3 21.78 23.24 22.06666667 1139.2 1189.97 1098.39 1052.41 1142.52 0.32330522 0.105954423 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031303///integral component of endosome membrane+++GO:1905103///integral component of lysosomal membrane GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0035751///regulation of lysosomal lumen pH+++GO:0070050///neuron cellular homeostasis+++GO:0071805///potassium ion transmembrane transport+++GO:0090385///phagosome-lysosome fusion 72393 72393 'Faim2' mRNA 2461 2586 2499 28.96 29.93 31.18 4.2 3.44 3.1 30.02333333 3.58 411 330 294 2515.333333 345 1.96E-183 -2.880292518 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005515///protein binding GO:0002931///response to ischemia+++GO:0006915///apoptotic process+++GO:0007417///central nervous system development+++GO:0021549///cerebellum development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021681///cerebellar granular layer development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0043523///regulation of neuron apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2001234///negative regulation of apoptotic signaling pathway 72397 72397 'Rbm12b1' mRNA 301.07 320.12 290.44 3.83 4.39 3.93 2.73 3.25 2.34 4.05 2.773333333 220.16 244.61 191.32 303.8766667 218.6966667 0.00387018 -0.486152781 GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0043484///regulation of RNA splicing 72399 72399 'Brap' mRNA 1314 1284 555 19.04 18.29 8.53 7.79 13.76 11.93 15.28666667 11.16 619 1066 918 1051 867.6666667 0.646954273 -0.264560074 04014///Ras signaling pathway GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0003676///nucleic acid binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000165///MAPK cascade+++GO:0007265///Ras protein signal transduction+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination 72400 72400 'Pinx1' mRNA 91 77 84 3.81 3.33 3.87 6.28 6.67 5.65 3.67 6.2 162 170 138 84 156.6666667 1.64E-04 0.886838088 "GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005819///spindle" GO:0003676///nucleic acid binding+++GO:0010521///telomerase inhibitor activity+++GO:0044877///protein-containing complex binding+++GO:0070034///telomerase RNA binding "GO:0007004///telomere maintenance via telomerase+++GO:0007080///mitotic metaphase plate congression+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity+++GO:0070198///protein localization to chromosome, telomeric region+++GO:1902570///protein localization to nucleolus+++GO:1904744///positive regulation of telomeric DNA binding+++GO:1904751///positive regulation of protein localization to nucleolus" 72401 72401 'Slc43a1' mRNA 336 302 374 7.7 7.02 9.03 3.6 3.5 3.59 7.916666667 3.563333333 180 167 158 337.3333333 168.3333333 3.43E-09 -1.020059955 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006865///amino acid transport+++GO:0015804///neutral amino acid transport+++GO:0015807///L-amino acid transport+++GO:0051956///negative regulation of amino acid transport+++GO:0055085///transmembrane transport+++GO:0060358///negative regulation of leucine import+++GO:1902475///L-alpha-amino acid transmembrane transport 72404 72404 'Wdr44' mRNA 318 305 345 4.1 3.88 4.75 4.91 4.04 4.28 4.243333333 4.41 438 352 370 322.6666667 386.6666667 0.133948874 0.244444469 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0031267///small GTPase binding GO:0030334///regulation of cell migration 72413 72413 'Kcnmb2' mRNA 63 64 42 0.59 0.6 0.42 0.07 0.03 0.08 0.536666667 0.06 18 8.22 11 56.33333333 12.40666667 3.16E-06 -2.199835145 04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04911///Insulin secretion GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005267///potassium channel activity+++GO:0015269///calcium-activated potassium channel activity+++GO:0015459///potassium channel regulator activity GO:0001508///action potential+++GO:0005513///detection of calcium ion+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0019228///neuronal action potential+++GO:0071805///potassium ion transmembrane transport 72415 72415 'Sgo1' mRNA 11 8 7 0.17 0.12 0.11 1.76 1.26 1.61 0.133333333 1.543333333 135 94 119 8.666666667 116 6.81E-20 3.730365939 04114///Oocyte meiosis "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton" GO:0019900///kinase binding "GO:0000070///mitotic sister chromatid segregation+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0010457///centriole-centriole cohesion+++GO:0045132///meiotic chromosome segregation+++GO:0045143///homologous chromosome segregation+++GO:0051177///meiotic sister chromatid cohesion+++GO:0051301///cell division+++GO:0071962///mitotic sister chromatid cohesion, centromeric" 72416 72416 'Lrpprc' mRNA 706 728.09 694.77 8.49 8.47 8.59 6.81 6.49 6.29 8.516666667 6.53 676.01 625 605 709.62 635.3366667 0.131444752 -0.171243442 GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005640///nuclear outer membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0042645///mitochondrial nucleoid+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048487///beta-tubulin binding+++GO:0051015///actin filament binding GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0051028///mRNA transport+++GO:0070129///regulation of mitochondrial translation 72421 72421 'Ttc30b' mRNA 1641.56 1812.66 1704.16 34.86 37.89 38.39 12.52 13.07 12.46 37.04666667 12.68333333 678.43 691.19 653.39 1719.46 674.3366667 1.26E-56 -1.362582571 GO:0005879///axonemal microtubule+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0120170///intraciliary transport particle B binding GO:0030030///cell projection organization+++GO:0042073///intraciliary transport 72425 72425 'Katnbl1' mRNA 624 656 639 11.92 12.34 12.95 11.63 12.33 11.82 12.40333333 11.92666667 700 725 689 639.6666667 704.6666667 0.291750821 0.127748267 GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole GO:0003674///molecular_function+++GO:0008017///microtubule binding GO:0051495///positive regulation of cytoskeleton organization 72429 72429 'Dnajc25' mRNA 206 169.09 187 3.55 2.61 2.73 2.31 2.38 2.77 2.963333333 2.486666667 186.95 174.3 189 187.3633333 183.4166667 0.863090843 -0.046912318 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006457///protein folding 72431 72431 'Ceacam18' mRNA 0 2 0 0 0.06 0 0.03 0.05 0.18 0.02 0.086666667 1 2 4 0.666666667 2.333333333 0.490962818 1.831563266 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72433 72433 'Rab38' mRNA 133 149 116 4.95 5.47 4.58 5.76 6.07 6.02 5 5.95 178 183 180 132.6666667 180.3333333 0.038574585 0.434936062 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0045335///phagocytic vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0030742///GTP-dependent protein binding+++GO:0035650///AP-1 adaptor complex binding+++GO:0035651///AP-3 adaptor complex binding+++GO:0036461///BLOC-2 complex binding GO:0006886///intracellular protein transport+++GO:0007005///mitochondrion organization+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032438///melanosome organization+++GO:0035646///endosome to melanosome transport+++GO:0060155///platelet dense granule organization+++GO:0072657///protein localization to membrane+++GO:0090383///phagosome acidification+++GO:1903232///melanosome assembly+++GO:2001247///positive regulation of phosphatidylcholine biosynthetic process 72434 72434 'Lypd3' mRNA 58 56 64 2.08 1.98 2.43 0.97 0.58 1.29 2.163333333 0.946666667 31 18 40 59.33333333 29.66666667 0.014239132 -1.017344152 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031225///anchored component of membrane GO:0043236///laminin binding GO:0006928///movement of cell or subcellular component+++GO:0007160///cell-matrix adhesion 72440 72440 'Rhno1' mRNA 869 863 893 25.03 24.86 28.59 21.16 21.95 21.98 26.16 21.69666667 836.74 818 807 875 820.58 0.35061594 -0.106343148 GO:0005634///nucleus+++GO:0005694///chromosome GO:0003674///molecular_function GO:0000077///DNA damage checkpoint+++GO:0000725///recombinational repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0034644///cellular response to UV+++GO:0070318///positive regulation of G0 to G1 transition+++GO:0071479///cellular response to ionizing radiation 72446 72446 'Prr5l' mRNA 286.5 296.96 319 3.57 3.65 4.22 6.42 6.26 6.58 3.813333333 6.42 584.86 560.56 594.52 300.82 579.98 2.51E-13 0.933717583 GO:0005739///mitochondrion+++GO:0031932///TORC2 complex GO:0031625///ubiquitin protein ligase binding GO:0001933///negative regulation of protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0009968///negative regulation of signal transduction+++GO:0010762///regulation of fibroblast migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0034599///cellular response to oxidative stress+++GO:0038203///TORC2 signaling+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0090316///positive regulation of intracellular protein transport 72454 72454 'Ccdc71' mRNA 733 847 573 13.08 14.87 10.84 11.98 12.42 12.52 12.93 12.30666667 774 783 782 717.6666667 779.6666667 0.419676455 0.114759331 GO:0005575///cellular_component GO:0003674///molecular_function 72459 72459 'Htatsf1' mRNA 1373 1439 1452 26.63 27.47 29.86 20.27 20.94 21.6 27.98666667 20.93666667 1194 1207 1237 1421.333333 1212.666667 0.006848949 -0.241936067 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005684///U2-type spliceosomal complex+++GO:0005686///U2 snRNP GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome" 72461 72461 'Prcp' mRNA 458 466 449 8.5 8.51 8.83 19.72 18.4 20.19 8.613333333 19.43666667 1223 1115 1213 457.6666667 1183.666667 9.91E-47 1.358736961 04614///Renin-angiotensin system+++04974///Protein digestion and absorption GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045178///basal part of cell GO:0004180///carboxypeptidase activity+++GO:0004185///serine-type carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0002353///plasma kallikrein-kinin cascade+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006508///proteolysis+++GO:0042593///glucose homeostasis+++GO:0043535///regulation of blood vessel endothelial cell migration+++GO:0060055///angiogenesis involved in wound healing+++GO:0097009///energy homeostasis+++GO:2000377///regulation of reactive oxygen species metabolic process 72462 72462 'Rrp1b' mRNA 403.24 396 388.46 4.55 4.36 4.64 4.8 5.05 4.6 4.516666667 4.816666667 492.55 506.23 453.71 395.9 484.1633333 0.035925642 0.278111954 "GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001652///granular component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0030687///preribosome, large subunit precursor+++GO:0030688///preribosome, small subunit precursor" GO:0003713///transcription coactivator activity+++GO:0005515///protein binding GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043484///regulation of RNA splicing+++GO:0043923///positive regulation by host of viral transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0098586///cellular response to virus 72465 72465 'Zfp131' mRNA 379 383 416 6.49 6.38 7.59 7.77 6.8 6.77 6.82 7.113333333 514 448 443 392.6666667 468.3333333 0.099138831 0.238760335 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0045111///intermediate filament cytoskeleton "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 72469 72469 'Plcd3' mRNA 876 952.9 748 15.75 16.46 14.28 8.38 7.99 8.59 15.49666667 8.32 540 521 538.44 858.9666667 533.1466667 2.79E-11 -0.695953293 00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032154///cleavage furrow GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0060716///labyrinthine layer blood vessel development 72472 72472 'Slc16a10' mRNA 371.08 407.81 212.41 5.9 6.8 3.78 3.04 5.49 5.49 5.493333333 4.673333333 282.91 485 419.94 330.4333333 395.95 0.29374614 0.266782461 04919///Thyroid hormone signaling pathway+++04974///Protein digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0015173///aromatic amino acid transmembrane transporter activity+++GO:0015349///thyroid hormone transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006590///thyroid hormone generation+++GO:0015801///aromatic amino acid transport+++GO:0055085///transmembrane transport+++GO:0070327///thyroid hormone transport+++GO:0070460///thyroid-stimulating hormone secretion 72475 72475 'Ssbp3' mRNA 936 857 803 19.51 17.54 18.03 20.42 14.13 16.82 18.36 17.12333333 1085 746 895 865.3333333 908.6666667 0.730938008 0.056918537 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0021501///prechordal plate formation+++GO:0021547///midbrain-hindbrain boundary initiation+++GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048382///mesendoderm development+++GO:0060322///head development+++GO:0060323///head morphogenesis+++GO:0065003///protein-containing complex assembly+++GO:2000744///positive regulation of anterior head development" 72477 72477 'Tmem87b' mRNA 1240 1426 1327 14.38 16.26 16.32 15.97 13.65 14.81 15.65333333 14.81 1585 1324 1424 1331 1444.333333 0.324567482 0.104354364 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function "GO:0006810///transport+++GO:0042147///retrograde transport, endosome to Golgi" 72479 72479 'Hsdl2' mRNA 1665 1665 1575 35.36 34.75 35.49 34.75 33.37 31.46 35.2 33.19333333 1884 1767 1650 1635 1767 0.251314598 0.100102842 GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity GO:0008150///biological_process 72480 72480 'Tspyl4' mRNA 2107 2054 2018 29.2 28 29.67 11.97 9.81 9.59 28.95666667 10.45666667 994 796 771 2059.666667 853.6666667 1.10E-44 -1.284788584 GO:0000785///chromatin+++GO:0005634///nucleus GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006334///nucleosome assembly+++GO:0008150///biological_process 72482 72482 'Acbd6' mRNA 644.93 677.33 507.57 31.19 32.85 26.32 21.97 34.94 36.1 30.12 31.00333333 494 728.59 753.46 609.9433333 658.6833333 0.584158852 0.109233249 GO:0005737///cytoplasm GO:0000062///fatty-acyl-CoA binding+++GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0008150///biological_process 72486 72486 'Obi1' mRNA 250.21 240.03 274 3.96 3.6 4.53 3.98 3.31 3.34 4.03 3.543333333 275 241 235.01 254.7466667 250.3366667 0.863090843 -0.040827967 GO:0000785///chromatin+++GO:0005694///chromosome GO:0003682///chromatin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding "GO:0006275///regulation of DNA replication+++GO:0006513///protein monoubiquitination+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0051865///protein autoubiquitination" 72500 72500 'Ier5l' mRNA 24 15 24 0.9 0.55 0.95 1.34 2.07 2.12 0.8 1.843333333 41 62 63 21 55.33333333 0.001692611 1.384689007 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72502 72502 'Cwf19l1' mRNA 249 257 249 4.4 4.46 4.88 3.48 3.87 4.13 4.58 3.826666667 218 235 243 251.6666667 232 0.522515341 -0.128519946 GO:0071014///post-mRNA release spliceosomal complex GO:0061632///RNA lariat debranching enzyme activator activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0050790///regulation of catalytic activity" 72503 72503 '2610507B11Rik' mRNA 3591 3459 2797 25.54 24.09 20.95 26.52 26.03 28.28 23.52666667 26.94333333 4313 4146 4467 3282.333333 4308.666667 1.61E-07 0.385179843 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 72504 72504 'Taf4b' mRNA 129 112 81 0.99 0.85 0.66 0.75 1 0.96 0.833333333 0.903333333 111 147 139 107.3333333 132.3333333 0.295225538 0.299539759 03022///Basal transcription factors+++05016///Huntington disease GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046982///protein heterodimerization activity+++GO:0051059///NF-kappaB binding "GO:0006351///transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:2000648///positive regulation of stem cell proliferation" 72507 72507 'Dzip1l' mRNA 338 347 327 4.04 3.96 3.99 2.29 1.75 1.64 3.996666667 1.893333333 226 176 160 337.3333333 187.3333333 2.66E-07 -0.862256317 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007224///smoothened signaling pathway+++GO:0021532///neural tube patterning+++GO:0032880///regulation of protein localization+++GO:0033365///protein localization to organelle+++GO:0033504///floor plate development+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1905349///ciliary transition zone assembly 72508 72508 'Rps6kb1' mRNA 1050 1219 1119 15 17.25 17.45 16.2 15.14 13.94 16.56666667 15.09333333 1162 1125 1066 1129.333333 1117.666667 0.841366337 -0.027028197 01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04350///TGF-beta signaling pathway+++04361///Axon regeneration+++04371///Apelin signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04714///Thermogenesis+++04910///Insulin signaling pathway+++04931///Insulin resistance+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05207///Chemical carcinogenesis - receptor activation+++05210///Colorectal cancer+++05212///Pancreatic cancer+++05221///Acute myeloid leukemia+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004711///ribosomal protein S6 kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0030165///PDZ domain binding+++GO:0042277///peptide binding+++GO:0042802///identical protein binding+++GO:0051721///protein phosphatase 2A binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0001662///behavioral fear response+++GO:0003009///skeletal muscle contraction+++GO:0006417///regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007281///germ cell development+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0007616///long-term memory+++GO:0009408///response to heat+++GO:0009611///response to wounding+++GO:0009612///response to mechanical stimulus+++GO:0009636///response to toxic substance+++GO:0009749///response to glucose+++GO:0010033///response to organic substance+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0014732///skeletal muscle atrophy+++GO:0014878///response to electrical stimulus involved in regulation of muscle adaptation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0018105///peptidyl-serine phosphorylation+++GO:0031667///response to nutrient levels+++GO:0031929///TOR signaling+++GO:0032496///response to lipopolysaccharide+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0033574///response to testosterone+++GO:0033762///response to glucagon+++GO:0034612///response to tumor necrosis factor+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043200///response to amino acid+++GO:0043201///response to leucine+++GO:0043434///response to peptide hormone+++GO:0043491///protein kinase B signaling+++GO:0044539///long-chain fatty acid import+++GO:0045471///response to ethanol+++GO:0045727///positive regulation of translation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0045948///positive regulation of translational initiation+++GO:0046324///regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051384///response to glucocorticoid+++GO:0071346///cellular response to interferon-gamma+++GO:0071363///cellular response to growth factor stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071549///cellular response to dexamethasone stimulus+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway 72512 72512 'Sting1' mRNA 797 805 925 20.26 19.62 24.81 44.34 44.83 42.83 21.56333333 44 2023 2003 1875 842.3333333 1967 1.73E-36 1.207691469 04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05131///Shigellosis+++05163///Human cytomegalovirus infection+++05168///Herpes simplex virus 1 infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19 GO:0000421///autophagosome membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:1990701///integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0016625///oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor+++GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035438///cyclic-di-GMP binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051536///iron-sulfur cluster binding+++GO:0061507///cyclic-GMP-AMP binding" GO:0000045///autophagosome assembly+++GO:0002218///activation of innate immune response+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0016239///positive regulation of macroautophagy+++GO:0022900///electron transport chain+++GO:0031323///regulation of cellular metabolic process+++GO:0032092///positive regulation of protein binding+++GO:0032481///positive regulation of type I interferon production+++GO:0032728///positive regulation of interferon-beta production+++GO:0035458///cellular response to interferon-beta+++GO:0045087///innate immune response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051259///protein complex oligomerization+++GO:0051607///defense response to virus+++GO:0061709///reticulophagy+++GO:0071360///cellular response to exogenous dsRNA+++GO:0071407///cellular response to organic cyclic compound 72514 72514 'Fgfbp3' mRNA 285 333 95 9.38 10.81 3.32 2.29 5.61 5.03 7.836666667 4.31 80 191 170 237.6666667 147 0.371313523 -0.6725629 GO:0005576///extracellular region GO:0008201///heparin binding+++GO:0017134///fibroblast growth factor binding+++GO:0019838///growth factor binding GO:0007267///cell-cell signaling+++GO:0030534///adult behavior+++GO:0031646///positive regulation of neurological system process+++GO:0043117///positive regulation of vascular permeability+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 72515 72515 'Wdr43' mRNA 803 769 749 12.67 11.94 12.53 13.28 13.88 14.23 12.38 13.79666667 969 989 1005 773.6666667 987.6666667 3.26E-04 0.341177208 03008///Ribosome biogenesis in eukaryotes GO:0000785///chromatin+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0000993///RNA polymerase II complex binding+++GO:0003711///transcription elongation regulator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006364///rRNA processing+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0042254///ribosome biogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:2000036///regulation of stem cell population maintenance+++GO:2000234///positive regulation of rRNA processing 72519 72519 'Pip4p2' mRNA 1376 1475 1301 33.82 35.72 33.95 35.89 34.69 34.77 34.49666667 35.11666667 1679 1586 1575 1384 1613.333333 0.007514488 0.210513429 04070///Phosphatidylinositol signaling system GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane "GO:0016787///hydrolase activity+++GO:0034597///phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity" GO:0046856///phosphatidylinositol dephosphorylation+++GO:0050765///negative regulation of phagocytosis 72522 72522 'Atxn7l2' mRNA 220 267 211 4.95 5.94 5.08 2.91 2.42 2.34 5.323333333 2.556666667 146 120 119 232.6666667 128.3333333 7.02E-06 -0.868719619 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72535 72535 'Aldh1b1' mRNA 62 36 45 1.51 0.86 1.16 3.12 2.54 2.87 1.176666667 2.843333333 147 117 131 47.66666667 131.6666667 3.72E-07 1.452110301 "00010///Glycolysis / Gluconeogenesis+++00053///Ascorbate and aldarate metabolism+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00561///Glycerolipid metabolism+++00620///Pyruvate metabolism+++00770///Pantothenate and CoA biosynthesis+++00981///Insect hormone biosynthesis+++01240///Biosynthesis of cofactors+++04936///Alcoholic liver disease" GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0006068///ethanol catabolic process 72536 72536 'Tagap' mRNA 73.5 61.67 73.24 1.35 1.09 1.38 4.43 4.51 4.67 1.273333333 4.536666667 283.24 284.5 286.76 69.47 284.8333333 9.82E-25 2.029588558 GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051607///defense response to virus 72542 72542 'Pgam5' mRNA 1015 1023 1023 27.7 27.51 29.62 23.62 23.76 24.55 28.27666667 23.97666667 995 977 1001 1020.333333 991 0.638804682 -0.054597692 04137///Mitophagy - animal+++04217///Necroptosis+++04668///TNF signaling pathway GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004722///protein serine/threonine phosphatase activity+++GO:0005096///GTPase activator activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0044877///protein-containing complex binding GO:0012501///programmed cell death+++GO:0016311///dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0070266///necroptotic process+++GO:0090141///positive regulation of mitochondrial fission+++GO:0120163///negative regulation of cold-induced thermogenesis 72543 72543 'Mvb12b' mRNA 1800.58 1742.68 1356.72 17.37 16.48 13.19 8.88 9.33 9.99 15.68 9.4 1126.02 1057.89 1159.06 1633.326667 1114.323333 2.28E-09 -0.55830626 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle GO:0008289///lipid binding GO:0015031///protein transport+++GO:0019075///virus maturation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0046755///viral budding 72544 72544 'Exosc6' mRNA 69.94 75.7 1.05 3.18 3.4 0.05 1 2.21 2.69 2.21 1.966666667 25.14 54.34 65.63 48.89666667 48.37 0.996140762 0.025170132 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding "GO:0006364///rRNA processing+++GO:0016075///rRNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0045006///DNA deamination+++GO:0045190///isotype switching+++GO:0045830///positive regulation of isotype switching+++GO:0071028///nuclear mRNA surveillance+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing" 72549 72549 'Reep4' mRNA 248 303 262 8.56 10.25 9.49 19.23 21.62 20.08 9.433333333 20.31 642 705 650 271 665.6666667 5.10E-24 1.28667142 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network GO:0008017///microtubule binding GO:0006998///nuclear envelope organization+++GO:0007049///cell cycle+++GO:0007084///mitotic nuclear envelope reassembly+++GO:0051301///cell division+++GO:0071786///endoplasmic reticulum tubular network organization 72552 72552 'Hsdl1' mRNA 1631 1615 1666 28.34 27.63 30.76 25.47 23.96 20.76 28.91 23.39666667 1682 1545 1332 1637.333333 1519.666667 0.255118455 -0.121984796 GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton GO:0003674///molecular_function+++GO:0016229///steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity GO:0008150///biological_process 72554 72554 'Utp14a' mRNA 252 287 273 5.79 6.49 6.65 8.59 7.53 7.61 6.31 7.91 430 368 369 270.6666667 389 5.82E-04 0.509697318 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0032040///small-subunit processome GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis 72555 72555 'Shisa9' mRNA 48 43 24 0.58 0.54 0.28 0.06 0.06 0.25 0.466666667 0.123333333 4 4 20 38.33333333 9.333333333 0.002038392 -2.034656822 GO:0005886///plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0032591///dendritic spine membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0030165///PDZ domain binding GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:2000311///regulation of AMPA receptor activity 72556 72556 'Zfp566' mRNA 135 134 156 4.64 4.54 5.68 3.11 3.28 3 4.953333333 3.13 104 107 97 141.6666667 102.6666667 0.048992869 -0.480030152 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72560 72560 'Naalad2' mRNA 103 124 121 1.44 1.71 1.79 1.8 1.58 1.64 1.646666667 1.673333333 148 127 131 116 135.3333333 0.438223365 0.208086354 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding+++GO:0050129///N-formylglutamate deformylase activity GO:0006508///proteolysis+++GO:0008152///metabolic process+++GO:0042135///neurotransmitter catabolic process 72562 72562 'Pcbd2' mRNA 239 254 97 34.48 37.09 14.98 13.99 24.65 24.73 28.85 21.12333333 109 187 185 196.6666667 160.3333333 0.429089495 -0.282981415 00790///Folate biosynthesis GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0004505///phenylalanine 4-monooxygenase activity+++GO:0005515///protein binding+++GO:0008124///4-alpha-hydroxytetrahydrobiopterin dehydratase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding "GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0019293///tyrosine biosynthetic process, by oxidation of phenylalanine+++GO:0045893///positive regulation of transcription, DNA-templated" 72565 72565 'Uaca' mRNA 2696 2730 2649 31.56 31.56 33.3 23.25 22.98 22.48 32.14 22.90333333 2288 2199 2149 2691.666667 2212 1.05E-05 -0.295437343 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0043293///apoptosome+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0009411///response to UV+++GO:0042307///positive regulation of protein import into nucleus+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050728///negative regulation of inflammatory response+++GO:0097190///apoptotic signaling pathway+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 72567 72567 'Bclaf1' mRNA 3030 3185 2860 33.21 33.79 32.71 27.92 24.89 26.68 33.23666667 26.49666667 2924 2544 2721 3025 2729.666667 0.021972494 -0.159799687 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016592///mediator complex+++GO:0016607///nuclear speck GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding "GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway" 72568 72568 'Lin9' mRNA 109 104 143 1.92 1.81 2.68 3.21 2.62 3.6 2.136666667 3.143333333 210 169 228 118.6666667 202.3333333 0.001111859 0.749840156 04218///Cellular senescence GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex GO:0003677///DNA binding "GO:0000003///reproduction+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0071897///DNA biosynthetic process" 72569 72569 'Bbs5' mRNA 493 441 426 19.42 17.15 17.74 8.05 7.27 7.54 18.10333333 7.62 235 206 211 453.3333333 217.3333333 1.99E-14 -1.072399832 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0034451///centriolar satellite+++GO:0034464///BBSome+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005515///protein binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0046907///intracellular transport+++GO:0060271///cilium assembly 72572 72572 'Spats2' mRNA 287 296 290 5.36 5.42 5.81 3.55 3.86 4.21 5.53 3.873333333 223 226 244 291 231 0.037411449 -0.34495861 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008150///biological_process 72580 72580 'Zup1' mRNA 521.39 517.34 563.33 8.63 8.57 9.53 9.81 8.46 8.03 8.91 8.766666667 604.69 541.16 506.69 534.02 550.8466667 0.863090843 0.028986953 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0010468///regulation of gene expression 72584 72584 'Cul4b' mRNA 514 540 436 5.49 5.67 4.94 6.3 5.35 5.73 5.366666667 5.793333333 679 563 598 496.6666667 613.3333333 0.017302533 0.294531604 03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003684///damaged DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010498///proteasomal protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031175///neuron projection development+++GO:0035518///histone H2A monoubiquitination+++GO:0042254///ribosome biogenesis+++GO:0045732///positive regulation of protein catabolic process+++GO:0070914///UV-damage excision repair+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 72585 72585 'Lypd1' mRNA 21.91 13.57 15.8 0.18 0.11 0.14 0.18 0.14 0.12 0.143333333 0.146666667 25.42 20.55 16.17 17.09333333 20.71333333 0.691360852 0.302475205 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045202///synapse GO:0005515///protein binding+++GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding "GO:0001662///behavioral fear response+++GO:0007271///synaptic transmission, cholinergic+++GO:0035094///response to nicotine+++GO:0095500///acetylcholine receptor signaling pathway+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000272///negative regulation of signaling receptor activity" 72587 72587 'Pan3' mRNA 1178.75 950.95 1063.12 10.91 8.96 9.47 9.72 7.91 9.73 9.78 9.12 1510.46 1240.36 1393.97 1064.273333 1381.596667 7.25E-04 0.361820336 03018///RNA degradation GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0031251///PAN complex GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008143///poly(A) binding+++GO:0046872///metal ion binding "GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006605///protein targeting+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 72590 72590 'Ppme1' mRNA 2599 2672 2523 61.64 62.4 63.48 47.45 45.51 45.44 62.50666667 46.13333333 2301 2155 2133 2598 2196.333333 1.47E-04 -0.25430063 GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0051721///protein phosphatase 2A binding+++GO:0051722///protein C-terminal methylesterase activity+++GO:0051723///protein methylesterase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006482///protein demethylation 72599 72599 'Pdia5' mRNA 53 53 40 1.69 1.66 1.35 3.96 5.05 5.41 1.566666667 4.806666667 143 178 189 48.66666667 170 1.92E-12 1.799189476 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0003756///protein disulfide isomerase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity GO:0006457///protein folding 72605 72605 'Car10' mRNA 2 2 1 0.04 0.04 0.02 0.03 0 0.04 0.033333333 0.023333333 2 0 3 1.666666667 1.666666667 0.998591786 -0.006951906 GO:0005575///cellular_component GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016836///hydro-lyase activity GO:0006730///one-carbon metabolic process 72607 72607 'Usp13' mRNA 42 52 32 0.42 0.47 0.3 0.39 0.3 0.27 0.396666667 0.32 42 31 27 42 33.33333333 0.496584731 -0.340498232 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0070628///proteasome binding+++GO:1904288///BAT3 complex binding+++GO:1990380///Lys48-specific deubiquitinase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0008283///cell proliferation+++GO:0010506///regulation of autophagy+++GO:0016579///protein deubiquitination+++GO:0035523///protein K29-linked deubiquitination+++GO:0044313///protein K6-linked deubiquitination+++GO:0050821///protein stabilization+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1904294///positive regulation of ERAD pathway+++GO:1904378///maintenance of unfolded protein involved in ERAD pathway" 72611 72611 'Zfp655' mRNA 751 767 828 13.18 12.9 14.87 14.84 17.79 15.39 13.65 16.00666667 948 1106 939 782 997.6666667 0.00375104 0.338247539 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle" 72612 72612 'Hpf1' mRNA 1077 1151 1061 44.56 48.37 45.43 39.39 42.02 39.5 46.12 40.30333333 1008 1029 1028 1096.333333 1021.666667 0.255805446 -0.11264232 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0090734///site of DNA damage GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0072572///poly-ADP-D-ribose binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010835///regulation of protein ADP-ribosylation+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:0031056///regulation of histone modification 72614 72614 'Pih1d2' mRNA 248 270 245.27 11.95 12.81 12.54 2.69 3.79 3.04 12.43333333 3.173333333 64 88.04 70 254.4233333 74.01333333 4.94E-18 -1.790206542 GO:0005737///cytoplasm+++GO:0097255///R2TP complex+++GO:1990904///ribonucleoprotein complex GO:0031267///small GTPase binding GO:0000492///box C/D snoRNP assembly+++GO:0006364///rRNA processing 72615 72615 'Anks3' mRNA 1046 1117 1071 23.95 24.86 25.95 18.14 18.43 17.75 24.92 18.10666667 915 874 851 1078 880 9.68E-04 -0.305210225 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0008150///biological_process 72621 72621 'Pdzd11' mRNA 1226 1293 1333.74 72.67 75.47 82.71 95.18 104.47 95.28 76.95 98.31 1832.53 1943.74 1761.21 1284.246667 1845.826667 6.00E-09 0.510074458 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0046930///pore complex+++GO:0098793///presynapse GO:0008022///protein C-terminus binding GO:0007269///neurotransmitter secretion+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0046931///pore complex assembly+++GO:1903361///protein localization to basolateral plasma membrane 72630 72630 'Hspa12b' mRNA 78 48 33 1.42 0.87 0.65 1.47 1.44 1.08 0.98 1.33 91 87 64 53 80.66666667 0.114392726 0.603005702 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 72632 72632 'Smim18' mRNA 223 203 205 29.37 26.63 28.66 5.08 6.06 5.27 28.22 5.47 44 51 44 210.3333333 46.33333333 2.22E-21 -2.193778578 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72634 72634 'Tdrkh' mRNA 758.61 739.41 735.67 16.86 14.9 17.68 8.17 9.81 8.49 16.48 8.823333333 347 390.37 360 744.5633333 365.79 1.49E-19 -1.036048349 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043186///P granule+++GO:0071546///pi-body+++GO:0071547///piP-body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation 72635 72635 'Lins1' mRNA 372 363 312 5.31 5 4.5 2.64 2.97 2.49 4.936666667 2.7 228 248 215 349 230.3333333 7.44E-05 -0.607990309 GO:0005575///cellular_component GO:0003674///molecular_function GO:0050890///cognition 72640 72640 'Mex3a' mRNA 128 106 106 1.09 0.89 0.96 0.72 0.95 0.78 0.98 0.816666667 97 126 102 113.3333333 108.3333333 0.834051226 -0.073936495 GO:0000932///P-body+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 72649 72649 'Tmem209' mRNA 829 827 922 12.82 12.59 15.16 14.06 12.37 12.68 13.52333333 13.03666667 1046 898 911 859.3333333 951.6666667 0.29188759 0.130809342 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 72650 72650 '2810006K23Rik' mRNA 399.67 403.04 492.43 13.77 13.71 18.01 10.43 11.44 11.58 15.16333333 11.15 347.85 373 373.64 431.7133333 364.83 0.114124177 -0.260072358 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit GO:0000049///tRNA binding+++GO:0003747///translation release factor activity+++GO:0043023///ribosomal large subunit binding GO:0006412///translation+++GO:0006415///translational termination+++GO:0072344///rescue of stalled ribosome 72654 72654 'Ccdc12' mRNA 1246.66 1174.54 1131.07 100.46 93.93 98.58 100.05 118.67 119.02 97.65666667 112.58 1404 1623.98 1610.29 1184.09 1546.09 6.28E-05 0.375356167 03040///Spliceosome GO:0005684///U2-type spliceosomal complex+++GO:0071014///post-mRNA release spliceosomal complex GO:0003674///molecular_function GO:0008150///biological_process 72656 72656 'Ints8' mRNA 229.58 252.46 218.68 3.03 3.08 2.89 3.13 2.81 3.3 3 3.08 272.66 221.31 296.22 233.5733333 263.3966667 0.420034979 0.163597452 GO:0005634///nucleus+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing 72657 72657 'Selenoh' mRNA 399 376 405 42.4 39.66 45.7 59.06 59 60.69 42.58666667 59.58333333 635 617 630 393.3333333 627.3333333 2.35E-08 0.660044563 GO:0005794///Golgi apparatus 72658 72658 '2700097O09Rik' mRNA 199 219 215 11.25 12.24 12.9 11.14 12.13 11.11 12.13 11.46 226 240 218 211 228 0.656260157 0.099610257 GO:0008168///methyltransferase activity 72661 72661 'Serp2' mRNA 10 25 11 0.82 1.98 0.97 1.04 2.1 2.41 1.256666667 1.85 15 28 32 15.33333333 25 0.306262685 0.709436143 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006486///protein glycosylation+++GO:0015031///protein transport+++GO:0030968///endoplasmic reticulum unfolded protein response 72662 72662 'Dis3' mRNA 261.26 245.14 258.9 5.02 4.94 4.91 5.72 5.72 6.78 4.956666667 6.073333333 363.15 317.35 347.39 255.1 342.63 0.007442924 0.413021384 03018///RNA degradation GO:0000176///nuclear exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000175///3'-5'-exoribonuclease activity+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0004540///ribonuclease activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0016787///hydrolase activity "GO:0006364///rRNA processing+++GO:0016075///rRNA catabolic process+++GO:0050790///regulation of catalytic activity+++GO:0071034///CUT catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 72667 72667 'Zfp444' mRNA 800.8 793 821.93 24.68 23.22 24.82 21.14 21.43 20.6 24.24 21.05666667 764 760.06 735.73 805.2433333 753.2633333 0.356373399 -0.108885846 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 72668 72668 'Skida1' mRNA 146 146 78 1.8 1.77 1.02 0.77 0.67 0.61 1.53 0.683333333 72 61 55 123.3333333 62.66666667 0.001097389 -0.97816665 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72672 72672 'Zfp518a' mRNA 342 328 246 2.65 2.51 2.02 1.8 1.55 1.73 2.393333333 1.693333333 267 225 249 305.3333333 247 0.074741326 -0.313251526 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II 72674 72674 'Adipor1' mRNA 5990 6118 3630 104.36 104.88 66.73 58.98 80.65 76.09 91.99 71.90666667 3952 5256 4916 5246 4708 0.64562461 -0.153082545 04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04920///Adipocytokine signaling pathway+++04932///Non-alcoholic fatty liver disease+++04936///Alcoholic liver disease GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0055100///adiponectin binding+++GO:0097003///adipokinetic hormone receptor activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0010633///negative regulation of epithelial cell migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010906///regulation of glucose metabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0019395///fatty acid oxidation+++GO:0030308///negative regulation of cell growth+++GO:0033210///leptin-mediated signaling pathway+++GO:0033211///adiponectin-activated signaling pathway+++GO:0042593///glucose homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 72685 72685 'Dnajc6' mRNA 394 437 414 4.07 4.46 4.57 1.25 1.42 1.22 4.366666667 1.296666667 140 155 132 415 142.3333333 3.08E-23 -1.555399935 04144///Endocytosis GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098793///presynapse GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0030276///clathrin binding GO:0006470///protein dephosphorylation+++GO:0016191///synaptic vesicle uncoating+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0072318///clathrin coat disassembly+++GO:0072583///clathrin-dependent endocytosis+++GO:2000369///regulation of clathrin-dependent endocytosis 72690 72690 'Grrp1' mRNA 129 158 85 5.46 6.57 4.07 4.23 7.59 6.73 5.366666667 6.183333333 110 192 171 124 157.6666667 0.255079049 0.350494097 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72691 72691 'Calhm2' mRNA 181 199 183 5.02 5.43 5.38 6.44 6.27 7.35 5.276666667 6.686666667 267 254 295 187.6666667 272 0.002314081 0.524157513 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005261///cation channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0043065///positive regulation of apoptotic process+++GO:0098655///cation transmembrane transport 72692 72692 'Hnrnpll' mRNA 708 751 236 12.74 13.29 4.5 5.08 5.81 8.04 10.17666667 6.31 325 363 498 565 395.3333333 0.420772961 -0.501810571 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006397///mRNA processing+++GO:0033120///positive regulation of RNA splicing+++GO:0043484///regulation of RNA splicing 72693 72693 'Zcchc12' mRNA 1583 1513 1580 40.94 38.54 43.31 4.01 4.63 4.27 40.93 4.303333333 179 200 182 1558.666667 187 3.54E-172 -3.071981818 GO:0005634///nucleus+++GO:0016605///PML body+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0032183///SUMO binding+++GO:0046872///metal ion binding GO:0030509///BMP signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II 72699 72699 'Lime1' mRNA 941 942 856 27.41 27.04 26.45 16.09 15.29 15.5 26.96666667 15.62666667 635 589 592 913 605.3333333 2.26E-10 -0.60381076 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019815///B cell receptor complex GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043405///regulation of MAP kinase activity+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:1901222///regulation of NIK/NF-kappaB signaling 72701 72701 'Zfp618' mRNA 126 144 132 0.74 0.83 0.82 0.66 0.68 0.69 0.796666667 0.676666667 129 129 132 134 130 0.863090843 -0.055066846 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin GO:0001221///transcription cofactor binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0035563///positive regulation of chromatin binding 72709 72709 'C1qtnf6' mRNA 90 97 83 2.19 2.28 2.1 5.36 6.73 5.59 2.19 5.893333333 265 318 265 90 282.6666667 1.56E-17 1.642783512 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0042802///identical protein binding 72713 72713 'Angptl1' mRNA 68 63 60 1.75 1.6 1.64 1.37 1.58 1.5 1.663333333 1.483333333 61 69 65 63.66666667 65 0.963035151 0.020165985 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding GO:0001525///angiogenesis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway 72720 72720 'Zfp248' mRNA 282 279 292 4.2 4.09 4.59 1.74 1.61 2.17 4.293333333 1.84 136 122 163 284.3333333 140.3333333 1.43E-08 -1.032366812 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72722 72722 'Fam98a' mRNA 669 659 603 13.13 12.77 12.53 16.96 14.4 15.22 12.81 15.52666667 994 826 863 643.6666667 894.3333333 6.65E-06 0.462512789 GO:0072669///tRNA-splicing ligase complex GO:0005515///protein binding+++GO:0008276///protein methyltransferase activity GO:0006479///protein methylation+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0032418///lysosome localization+++GO:1900029///positive regulation of ruffle assembly 72723 72723 'Zfp74' mRNA 441 406 417 6.04 5.45 6.08 3.13 3.24 3.31 5.856666667 3.226666667 262 266 269 421.3333333 265.6666667 1.05E-06 -0.677451282 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72726 72726 'Tbcc' mRNA 1147 1121 1149 35.77 34.45 38.01 26.45 28.52 30.28 36.07666667 28.41666667 975 1026 1080 1139 1027 0.114888333 -0.161519679 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032391///photoreceptor connecting cilium GO:0003924///GTPase activity+++GO:0015631///tubulin binding GO:0000902///cell morphogenesis+++GO:0006457///protein folding+++GO:0007021///tubulin complex assembly+++GO:0007023///post-chaperonin tubulin folding pathway 72727 72727 'B3gat3' mRNA 641 662 598 23.72 24.16 23.48 23.19 23.14 24.87 23.78666667 23.73333333 720 701 747 633.6666667 722.6666667 0.105690049 0.179116 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015018///galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0072542///protein phosphatase activator activity GO:0005975///carbohydrate metabolic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0006486///protein glycosylation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0043085///positive regulation of catalytic activity+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process+++GO:0050651///dermatan sulfate proteoglycan biosynthetic process+++GO:0090316///positive regulation of intracellular protein transport 72729 72729 'Cdc42se2' mRNA 1487 1504 1503 25.89 25.61 27.61 38.92 37.1 41.19 26.37 39.07 2576 2409 2644 1498 2543 7.50E-25 0.750624675 GO:0001891///phagocytic cup+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection GO:0031267///small GTPase binding+++GO:0035591///signaling adaptor activity GO:0006909///phagocytosis+++GO:0008360///regulation of cell shape+++GO:0009966///regulation of signal transduction+++GO:0035023///regulation of Rho protein signal transduction 72736 72736 'Tmx1' mRNA 1411 1543 1456 34.11 36.73 37.34 46.98 44.46 46.56 36.06 46 2235 2065 2144 1470 2148 4.50E-13 0.534726688 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015036///disulfide oxidoreductase activity GO:0034976///response to endoplasmic reticulum stress 72739 72739 'Zkscan3' mRNA 1189.89 1140.71 1097.73 28.07 26.4 27.47 25.45 23.26 22.72 27.31333333 23.81 1240.93 1121.01 1131.02 1142.776667 1164.32 0.887747656 0.01544063 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006914///autophagy+++GO:0007040///lysosome organization+++GO:0010507///negative regulation of autophagy+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000773///negative regulation of cellular senescence" 72745 72745 'Tmem161b' mRNA 671.41 664.48 699.78 8.22 8.26 9.32 5.78 6.17 5.82 8.6 5.923333333 547.71 542.79 522.94 678.5566667 537.8133333 0.002270962 -0.349931639 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 72747 72747 'Ttc39c' mRNA 209 211 70 3.99 4.21 1.34 1.63 2.13 2.39 3.18 2.05 93 113 125 163.3333333 110.3333333 0.111906899 -0.555071484 GO:0005575///cellular_component GO:0003674///molecular_function GO:0032474///otolith morphogenesis+++GO:0060271///cilium assembly 72748 72748 'Hdhd3' mRNA 342 368 347 19.82 21.07 21.33 22.08 22.07 21.69 20.74 21.94666667 437 426 415 352.3333333 426 0.058186033 0.262103015 GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle GO:0016787///hydrolase activity 72749 72749 'Tonsl' mRNA 109 142 131 1.4 1.79 1.78 2.23 1.92 1.86 1.656666667 2.003333333 199 168 161 127.3333333 176 0.044092801 0.452928935 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0035101///FACT complex+++GO:0042555///MCM complex+++GO:0043596///nuclear replication fork GO:0042393///histone binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing 72750 72750 'Fam117b' mRNA 317 342 286 3.05 3.23 2.92 2.73 2.14 2.62 3.066666667 2.496666667 327 250 304 315 293.6666667 0.560077004 -0.112252424 GO:0003674///molecular_function GO:0008150///biological_process 72754 72754 'Arhgef10l' mRNA 1241 1200 1210 14.95 14.29 15.48 13.76 14.15 14.27 14.90666667 14.06 1316 1315 1320 1217 1317 0.287342354 0.101683359 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton GO:0004407///histone deacetylase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0008134///transcription factor binding GO:0016575///histone deacetylation+++GO:0030036///actin cytoskeleton organization+++GO:0032933///SREBP signaling pathway+++GO:0050790///regulation of catalytic activity+++GO:0051496///positive regulation of stress fiber assembly 72759 72759 'Tmem135' mRNA 1188.13 1243.48 1223.53 18.5 19.13 19.65 15.51 13.66 14.38 19.09333333 14.51666667 1173.13 1018.47 1083 1218.38 1091.533333 0.072003026 -0.172035035 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0007031///peroxisome organization+++GO:0008340///determination of adult lifespan+++GO:0009409///response to cold+++GO:0010628///positive regulation of gene expression+++GO:0010884///positive regulation of lipid storage+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0032094///response to food+++GO:0090140///regulation of mitochondrial fission 72772 72772 'Rint1' mRNA 1030.94 933.42 1049.72 11.37 11.13 12.46 10.87 11.37 11.23 11.65333333 11.15666667 1219.87 1228.8 1200.27 1004.693333 1216.313333 0.009302605 0.261811613 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0070939///Dsl1/NZR complex "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007049///cell cycle+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048193///Golgi vesicle transport+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint" 72774 72774 'Neil1' mRNA 315 336 328 8.68 9.03 9.45 9.22 9.34 8.54 9.053333333 9.033333333 362 363 324 326.3333333 349.6666667 0.632785501 0.087223423 03410///Base excision repair GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008022///protein C-terminus binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016829///lyase activity+++GO:0019104///DNA N-glycosylase activity+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity" GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0008152///metabolic process+++GO:0032074///negative regulation of nuclease activity 72775 72775 'Fance' mRNA 532 513 399 15.24 14.46 12.16 7.6 11.06 12.83 13.95333333 10.49666667 304 437 500 481.3333333 413.6666667 0.267390166 -0.221336315 03460///Fanconi anemia pathway GO:0043240///Fanconi anaemia nuclear complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0036297///interstrand cross-link repair 72776 72776 'Sass6' mRNA 233.14 224.98 251.62 2.88 2.75 3.34 3.91 3.83 3.49 2.99 3.743333333 352.35 342.19 304.81 236.58 333.1166667 0.003064668 0.480552992 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite+++GO:0098536///deuterosome GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007099///centriole replication+++GO:0051298///centrosome duplication 72778 72778 'Dnajc22' mRNA 4 11 7 0.17 0.47 0.3 0.21 0.27 0.39 0.313333333 0.29 6 7 11 7.333333333 8 0.919405418 0.119296757 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane 72780 72780 'Rspo3' mRNA 3750 4009 3963 87.49 92.09 98.08 48.72 49.25 47.5 92.55333333 48.49 2402 2371 2267 3907.333333 2346.666667 6.28E-28 -0.748675182 04310///Wnt signaling pathway GO:0005576///extracellular region GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0008201///heparin binding GO:0001525///angiogenesis+++GO:0001974///blood vessel remodeling+++GO:0002040///sprouting angiogenesis+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0050896///response to stimulus+++GO:0060173///limb development+++GO:0060670///branching involved in labyrinthine layer morphogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway 72787 72787 'Ndc1' mRNA 405 375 390 5.04 4.59 5.15 6.01 6.01 6.32 4.926666667 6.113333333 556 543 566 390 555 4.80E-05 0.496503601 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0070762///nuclear pore transmembrane ring "GO:0017056///structural constituent of nuclear pore+++GO:0030674///protein binding, bridging" GO:0006913///nucleocytoplasmic transport+++GO:0006999///nuclear pore organization+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0051664///nuclear pore localization 72789 72789 'Veph1' mRNA 2332.34 2389.89 2126.14 19.91 20.15 19.23 4.63 4.04 4.29 19.76333333 4.32 625.13 521.49 562 2282.79 569.54 3.93E-135 -2.014456664 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0010314///phosphatidylinositol-5-phosphate binding GO:0009966///regulation of signal transduction+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060392///negative regulation of SMAD protein signal transduction 72792 72792 '2810459M11Rik' mRNA 76 81 62 1.25 1.31 1.08 0.57 0.63 0.65 1.213333333 0.616666667 40 43 44 73 42.33333333 0.018670748 -0.792832394 GO:0005575///cellular_component GO:0005515///protein binding GO:0008150///biological_process 72795 72795 'Ttc19' mRNA 254 262 247 4.46 4.74 4.98 3.61 2.65 3.78 4.726666667 3.346666667 222 160 230 254.3333333 204 0.091287415 -0.331485285 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0005515///protein binding GO:0034551///mitochondrial respiratory chain complex III assembly 72805 72805 'Zfp839' mRNA 351.41 348.29 271.04 4.63 4.45 3.56 2.73 2.5 2.67 4.213333333 2.633333333 245 215 228 323.58 229.3333333 0.001739971 -0.503651283 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72807 72807 'Zfp429' mRNA 115.39 139.13 129.36 3.01 3.65 3.62 4.3 5.02 3.52 3.426666667 4.28 194.56 216.95 156.1 127.96 189.2033333 0.013335518 0.551908632 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72821 72821 'Scn2b' mRNA 31 22 44 0.37 0.26 0.55 0.49 0.48 0.41 0.393333333 0.46 48 45 39 32.33333333 44 0.40237796 0.419759977 GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005244///voltage-gated ion channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005272///sodium channel activity+++GO:0017080///sodium channel regulator activity+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0007399///nervous system development+++GO:0034765///regulation of ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0046684///response to pyrethroid+++GO:0060048///cardiac muscle contraction+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:2000649///regulation of sodium ion transmembrane transporter activity 72823 72823 'Pard3b' mRNA 689 668 504 4.06 3.75 2.99 0.77 1.04 0.97 3.6 0.926666667 155 197 194 620.3333333 182 1.11E-31 -1.773151363 GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043296///apical junction complex GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding GO:0000226///microtubule cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0008104///protein localization+++GO:0030010///establishment of cell polarity+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0051301///cell division+++GO:0051660///establishment of centrosome localization 72825 72825 'Mon1a' mRNA 395 363 418 10.7 9.72 12.05 9.87 9.48 10.14 10.82333333 9.83 419 392 416 392 409 0.811289805 0.046096401 GO:0035658///Mon1-Ccz1 complex GO:0005085///guanyl-nucleotide exchange factor activity GO:0006623///protein targeting to vacuole+++GO:0006879///cellular iron ion homeostasis+++GO:0009306///protein secretion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0050790///regulation of catalytic activity 72826 72826 'Fam76b' mRNA 388.79 474.31 353.4 4.58 5.3 4.25 3.95 3.89 4.41 4.71 4.083333333 419.37 388.01 442.49 405.5 416.6233333 0.863090843 0.03190125 GO:0005634///nucleus+++GO:0016607///nuclear speck 72828 72828 'Ubash3b' mRNA 2444 2396 2104 22.73 21.99 20.14 7.75 9.11 7.76 21.62 8.206666667 960 1046 923 2314.666667 976.3333333 5.13E-55 -1.254074235 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding GO:0006469///negative regulation of protein kinase activity+++GO:0009968///negative regulation of signal transduction+++GO:0030168///platelet activation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0038065///collagen-activated signaling pathway+++GO:0043393///regulation of protein binding+++GO:0045670///regulation of osteoclast differentiation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045779///negative regulation of bone resorption+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0070527///platelet aggregation+++GO:0090331///negative regulation of platelet aggregation 72831 72831 'Dhx30' mRNA 2012 1986 2085 26.74 25.73 29.25 16.61 17.82 18.32 27.24 17.58333333 1437 1509 1544 2027.666667 1496.666667 5.78E-08 -0.451109615 GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0007417///central nervous system development+++GO:0042254///ribosome biogenesis+++GO:1902775///mitochondrial large ribosomal subunit assembly 72832 72832 'Crtac1' mRNA 58 57 37 1.45 1.29 1.07 0.26 0.37 0.31 1.27 0.313333333 11 17 12 50.66666667 13.33333333 4.60E-05 -1.926992434 GO:0005576///extracellular region+++GO:0030426///growth cone GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007413///axonal fasciculation+++GO:0021772///olfactory bulb development+++GO:1900121///negative regulation of receptor binding 72836 72836 'Pot1b' mRNA 178.03 157.91 143.51 2.19 1.98 1.88 1.5 1.3 1.41 2.016666667 1.403333333 129.66 111.7 129.07 159.8166667 123.4766667 0.091656441 -0.383750809 "GO:0000781///chromosome, telomeric region+++GO:0000783///nuclear telomere cap complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0070187///shelterin complex" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0031267///small GTPase binding+++GO:0042162///telomeric DNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0061821///telomeric D-loop binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:1990955///G-rich single-stranded DNA binding GO:0000723///telomere maintenance+++GO:0001558///regulation of cell growth+++GO:0007004///telomere maintenance via telomerase+++GO:0007569///cell aging+++GO:0016233///telomere capping+++GO:0031627///telomeric loop formation+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0032202///telomere assembly+++GO:0032210///regulation of telomere maintenance via telomerase+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032508///DNA duplex unwinding+++GO:0043087///regulation of GTPase activity+++GO:0043247///telomere maintenance in response to DNA damage+++GO:0048239///negative regulation of DNA recombination at telomere+++GO:0050764///regulation of phagocytosis+++GO:0051096///positive regulation of helicase activity+++GO:0051276///chromosome organization+++GO:0051973///positive regulation of telomerase activity+++GO:0051974///negative regulation of telomerase activity+++GO:0060383///positive regulation of DNA strand elongation+++GO:0061820///telomeric D-loop disassembly+++GO:0070200///establishment of protein localization to telomere+++GO:1905774///regulation of DNA helicase activity+++GO:1905776///positive regulation of DNA helicase activity+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining 72843 72843 'Prdm4' mRNA 307 338 188 4.47 4.78 3.15 2.45 2.71 2.54 4.133333333 2.566666667 179 192 190 277.6666667 187 0.006234892 -0.57041304 04722///Neurotrophin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005123///death receptor binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:1990226///histone methyltransferase binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006366///transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030308///negative regulation of cell growth+++GO:0032259///methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000177///regulation of neural precursor cell proliferation+++GO:2000736///regulation of stem cell differentiation 72844 72844 'Kctd17' mRNA 280 280 182 6.85 6.76 4.83 6.3 7.21 6.71 6.146666667 6.74 288 297 291 247.3333333 292 0.230703218 0.236091775 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0042802///identical protein binding+++GO:0097602///cullin family protein binding GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045724///positive regulation of cilium assembly+++GO:0051260///protein homooligomerization 72852 72852 'Mblac2' mRNA 425 455 442 5.92 6.23 6.53 3.66 2.84 3.55 6.226666667 3.35 302 229 284 440.6666667 271.6666667 1.02E-06 -0.712077392 GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0008150///biological_process 72865 72865 'Rtl8c' mRNA 815.02 753.53 690.02 55.35 50.63 49.72 49.03 49.41 47.58 51.9 48.67333333 827.45 812.7 775.8 752.8566667 805.3166667 0.474507999 0.086287366 GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 72873 72873 'Bbof1' mRNA 414.72 428.97 387.54 7.67 7.69 7.32 1.34 1.23 1.52 7.56 1.363333333 113.35 109.76 117.49 410.41 113.5333333 1.77E-32 -1.868760062 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process+++GO:0044458///motile cilium assembly 72881 72881 'Zdhhc4' mRNA 871 964 931 37.22 40.58 42.11 33.73 31.79 30.28 39.97 31.93333333 923 834 788 922 848.3333333 0.244138081 -0.133651431 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation 72886 72886 'Yju2' mRNA 294 262 262 13.52 11.9 12.79 10.42 11.34 11.47 12.73666667 11.07666667 260 276 277 272.6666667 271 0.924712163 -0.019663843 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071006///U2-type catalytic step 1 spliceosome GO:0003674///molecular_function+++GO:0046872///metal ion binding "GO:0000349///generation of catalytic spliceosome for first transesterification step+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator" 72891 72891 'Xlr4c' mRNA 6.89 5 0 0.34 0.25 0 1.55 0.8 1.1 0.196666667 1.15 35.62 16.86 24.33 3.963333333 25.60333333 7.86E-04 2.770536583 GO:0000795///synaptonemal complex+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle 72895 72895 'Setd5' mRNA 1899 1730 1277 12.71 11.43 8.73 10.43 9.22 9.42 10.95666667 9.69 1803 1528 1560 1635.333333 1630.333333 0.942313116 -0.01075856 GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016593///Cdc73/Paf1 complex GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0006325///chromatin organization+++GO:0016569///covalent chromatin modification+++GO:0032259///methylation+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0035065///regulation of histone acetylation+++GO:0050890///cognition+++GO:0051567///histone H3-K9 methylation+++GO:0051963///regulation of synapse assembly+++GO:0097198///histone H3-K36 trimethylation+++GO:1902275///regulation of chromatin organization" 72898 72898 'Asphd2' mRNA 291 293 272 5.05 5.06 5.36 0.59 0.8 0.59 5.156666667 0.66 37 49 39 285.3333333 41.66666667 2.91E-37 -2.785402831 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity GO:0008150///biological_process+++GO:0018193///peptidyl-amino acid modification 72899 72899 'Macrod2' mRNA 267 311 119 5.36 6.17 2.14 0.95 1.04 0.99 4.556666667 0.993333333 61 68 65 232.3333333 64.66666667 1.92E-10 -1.83786137 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0003674///molecular_function+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019213///deacetylase activity" GO:0006974///cellular response to DNA damage stimulus+++GO:0007420///brain development+++GO:0009617///response to bacterium+++GO:0042278///purine nucleoside metabolic process+++GO:0051725///protein de-ADP-ribosylation 72900 72900 'Ndufv2' mRNA 3544 3756.99 3698.99 135.42 141.61 149.94 149.58 158.26 152.61 142.3233333 153.4833333 4496 4641.99 4437.99 3666.66 4525.326667 1.48E-05 0.2911982 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070469///respiratory chain "GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0007399///nervous system development+++GO:0048738///cardiac muscle tissue development" 72902 72902 'Spock3' mRNA 389 372 339 6.73 6.33 6.26 1.53 1.11 1.42 6.44 1.353333333 103 73 90 366.6666667 88.66666667 4.91E-31 -2.060003123 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0004857///enzyme inhibitor activity+++GO:0005509///calcium ion binding+++GO:0005539///glycosaminoglycan binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 72925 72925 'Marchf1' mRNA 921.85 942.45 670.59 4.34 4.29 3.37 5.46 5.34 4.54 4 5.113333333 995.37 887.31 830.19 844.9633333 904.29 0.522515341 0.092148229 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032588///trans-Golgi network membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042287///MHC protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0002495///antigen processing and presentation of peptide antigen via MHC class II+++GO:0006955///immune response+++GO:0016567///protein ubiquitination 72927 72927 'Hepacam' mRNA 1213 1202 1088 21.52 20.99 20.48 8.96 7.01 9.94 20.99666667 8.636666667 581 444 624 1167.666667 549.6666667 4.43E-22 -1.09870022 GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0007155///cell adhesion+++GO:0034613///cellular protein localization+++GO:0040008///regulation of growth+++GO:0051726///regulation of cell cycle 72930 72930 'Ppp2r2b' mRNA 3798.39 4112.68 3702.39 49.12 53.87 57.03 14.88 15.54 14.21 53.34 14.87666667 1225.13 1167.86 1087.53 3871.153333 1160.173333 3.91E-144 -1.750140347 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane GO:0019888///protein phosphatase regulator activity+++GO:0044877///protein-containing complex binding GO:0000266///mitochondrial fission+++GO:0006626///protein targeting to mitochondrion+++GO:0006915///apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0050790///regulation of catalytic activity+++GO:0070262///peptidyl-serine dephosphorylation 72931 72931 'Swi5' mRNA 3685 3684 3323 330.02 328.67 317.3 354.95 356.1 363.32 325.33 358.1233333 4527 4424 4487 3564 4479.333333 1.34E-08 0.319558783 GO:0005634///nucleus+++GO:0032798///Swi5-Sfr1 complex+++GO:0034974///Swi5-Swi2 complex GO:0005515///protein binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0071479///cellular response to ionizing radiation 72935 72935 'Ddx41' mRNA 1083 1124 1212 27.97 28.63 33.22 33.37 34.68 33.56 29.94 33.87 1493 1517 1454 1139.666667 1488 8.21E-05 0.370357776 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005783///endoplasmic reticulum+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008283///cell proliferation+++GO:0008380///RNA splicing+++GO:0030154///cell differentiation+++GO:0035458///cellular response to interferon-beta+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus" 72938 72938 'Hspb11' mRNA 313.82 277.1 249.38 26.33 22.9 22.98 19.8 21.2 21.67 24.07 20.89 241.55 223.84 244.64 280.1 236.6766667 0.147631617 -0.254564029 GO:0005813///centrosome+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030992///intraciliary transport particle B+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0001501///skeletal system development+++GO:0001822///kidney development+++GO:0007224///smoothened signaling pathway+++GO:0007283///spermatogenesis+++GO:0007507///heart development+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly+++GO:0070986///left/right axis specification 72946 72946 'Lrrc47' mRNA 184.57 218.09 157.25 2.96 3.44 2.68 3.11 2.23 2.52 3.026666667 2.62 223.06 156.53 174.9 186.6366667 184.83 0.92535794 -0.025346318 GO:0005575///cellular_component GO:0003723///RNA binding+++GO:0004826///phenylalanine-tRNA ligase activity GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0008150///biological_process 72947 72947 'Phykpl' mRNA 486.58 413.58 491.21 14.05 11.78 15.18 10.44 9.15 8.59 13.67 9.393333333 415.3 353.27 335.5 463.79 368.0233333 0.02119562 -0.350228322 00310///Lysine degradation GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008483///transaminase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding GO:0008150///biological_process 72948 72948 'Tppp' mRNA 346 414 412 3.58 4.25 4.56 0.54 0.41 0.41 4.13 0.453333333 60 44 44 390.6666667 49.33333333 5.20E-49 -3.001095326 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0043209///myelin sheath+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle+++GO:0097427///microtubule bundle+++GO:0150051///postsynaptic Golgi apparatus GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding GO:0001578///microtubule bundle formation+++GO:0007049///cell cycle+++GO:0014003///oligodendrocyte development+++GO:0030953///astral microtubule organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031643///positive regulation of myelination+++GO:0032273///positive regulation of protein polymerization+++GO:0032288///myelin assembly+++GO:0046785///microtubule polymerization+++GO:0048709///oligodendrocyte differentiation+++GO:0051301///cell division+++GO:0051418///microtubule nucleation by microtubule organizing center+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1904428///negative regulation of tubulin deacetylation 72949 72949 'Ccnt2' mRNA 869 908 881 13.45 13.82 14.46 11.06 9.7 10.73 13.91 10.49666667 823 705 773 886 767 0.034418987 -0.221348663 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0048471///perinuclear region of cytoplasm GO:0001223///transcription coactivator binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0061575///cyclin-dependent protein serine/threonine kinase activator activity+++GO:0070063///RNA polymerase binding+++GO:0097322///7SK snRNA binding "GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007519///skeletal muscle tissue development+++GO:0016032///viral process+++GO:0019085///early viral transcription+++GO:0019086///late viral transcription+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity+++GO:0051147///regulation of muscle cell differentiation+++GO:0051301///cell division" 72958 72958 'Zfp493' mRNA 26 31 13 0.43 0.51 0.23 0.33 0.4 0.49 0.39 0.406666667 23 27 33 23.33333333 27.66666667 0.717289488 0.249408066 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 72960 72960 'Top1mt' mRNA 267 278 236 8 8.16 7.48 5.37 5.82 6.36 7.88 5.85 206 218 236 260.3333333 220 0.166349737 -0.251431632 GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005739///mitochondrion+++GO:0042645///mitochondrial nucleoid GO:0003677///DNA binding+++GO:0003916///DNA topoisomerase activity+++GO:0003917///DNA topoisomerase type I activity+++GO:0016853///isomerase activity GO:0006260///DNA replication+++GO:0006265///DNA topological change 72961 72961 'Slc17a7' mRNA 4 3 0 0.07 0.06 0 0.07 0.05 0.05 0.043333333 0.056666667 4 3 3 2.333333333 3.333333333 0.799001769 0.527822058 04721///Synaptic vesicle cycle+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++05033///Nicotine addiction GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0043229///intracellular organelle+++GO:0044300///cerebellar mossy fiber+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0008068///extracellularly glutamate-gated chloride channel activity+++GO:0015293///symporter activity+++GO:0015319///sodium:inorganic phosphate symporter activity+++GO:0022857///transmembrane transporter activity "GO:0003407///neural retina development+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006817///phosphate ion transport+++GO:0006820///anion transport+++GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0007420///brain development+++GO:0007616///long-term memory+++GO:0015813///L-glutamate transmembrane transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035725///sodium ion transmembrane transport+++GO:0042137///sequestering of neurotransmitter+++GO:0050803///regulation of synapse structure or activity+++GO:0050896///response to stimulus+++GO:0051938///L-glutamate import+++GO:0055085///transmembrane transport+++GO:0060079///excitatory postsynaptic potential+++GO:0097401///synaptic vesicle lumen acidification+++GO:0098700///neurotransmitter loading into synaptic vesicle+++GO:1900242///regulation of synaptic vesicle endocytosis" 72962 72962 'Tymp' mRNA 70.25 87.32 59.52 1.69 2.07 1.52 0.54 0.69 0.68 1.76 0.636666667 25.93 32.21 31.58 72.36333333 29.90666667 3.45E-04 -1.299491343 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++05219///Bladder cancer GO:0005829///cytosol "GO:0004645///phosphorylase activity+++GO:0009032///thymidine phosphorylase activity+++GO:0016154///pyrimidine-nucleoside phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042803///protein homodimerization activity" GO:0000002///mitochondrial genome maintenance+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0006935///chemotaxis+++GO:0009887///animal organ morphogenesis+++GO:0031641///regulation of myelination+++GO:0046074///dTMP catabolic process+++GO:0051969///regulation of transmission of nerve impulse+++GO:1905333///regulation of gastric motility 72972 72972 'Ccser2' mRNA 2782 2865 2647 21.82 22.05 22.3 16.02 16.17 15.4 22.05666667 15.86333333 2348 2344 2176 2764.666667 2289.333333 2.75E-05 -0.283194693 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton GO:0008017///microtubule binding GO:0001578///microtubule bundle formation 72973 72973 'Fbxo47' mRNA 22 24 17 0.2 0.23 0.16 0.15 0.15 0.14 0.196666667 0.146666667 18 19 18 21 18.33333333 0.785645999 -0.201759298 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 72978 72978 'Cnih3' mRNA 167 194 125 3.22 3.85 2.65 0.25 0.49 0.32 3.24 0.353333333 17 33 23 162 24.33333333 1.11E-18 -2.735575519 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032281///AMPA glutamate receptor complex+++GO:0043198///dendritic shaft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse GO:0016247///channel regulator activity "GO:0016192///vesicle-mediated transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:0042391///regulation of membrane potential+++GO:0051668///localization within membrane+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:2000311///regulation of AMPA receptor activity" 72981 72981 'Thap12' mRNA 401.54 401.7 372.59 6.02 5.93 5.98 6.61 5.81 6.51 5.976666667 6.31 505.95 434.83 482.26 391.9433333 474.3466667 0.046901787 0.263636018 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity GO:0008150///biological_process 72982 72982 'Tmem138' mRNA 732.12 758.25 713.09 28.94 29.37 29.88 17.75 18.13 17.67 29.39666667 17.85 524.87 523.65 514.94 734.4866667 521.1533333 1.16E-06 -0.508332023 GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 72993 72993 'Appl1' mRNA 1520 1483 1265 11.54 11.07 10.18 9.29 9.03 8.99 10.93 9.103333333 1410 1338 1322 1422.666667 1356.666667 0.423714631 -0.077730222 04211///Longevity regulating pathway+++05200///Pathways in cancer+++05210///Colorectal cancer GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032009///early phagosome+++GO:0042995///cell projection+++GO:0044354///macropinosome+++GO:0045335///phagocytic vesicle+++GO:0097708///intracellular vesicle GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043422///protein kinase B binding+++GO:0044877///protein-containing complex binding+++GO:0048487///beta-tubulin binding GO:0006606///protein import into nucleus+++GO:0007049///cell cycle+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0008286///insulin receptor signaling pathway+++GO:0010762///regulation of fibroblast migration+++GO:0023052///signaling+++GO:0033211///adiponectin-activated signaling pathway+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0045088///regulation of innate immune response+++GO:0046324///regulation of glucose import+++GO:0046326///positive regulation of glucose import+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:1903076///regulation of protein localization to plasma membrane+++GO:1905303///positive regulation of macropinocytosis+++GO:1905450///negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:2000045///regulation of G1/S transition of mitotic cell cycle 72999 72999 'Insig2' mRNA 1791 1908 1704 37.94 39.79 38.44 49.4 47.57 44.83 38.72333333 47.26666667 2621 2448 2317 1801 2462 5.33E-10 0.439887492 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032937///SREBP-SCAP-Insig complex GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008142///oxysterol binding+++GO:0008289///lipid binding GO:0006629///lipid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006991///response to sterol depletion+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0032868///response to insulin+++GO:0032869///cellular response to insulin stimulus+++GO:0032933///SREBP signaling pathway+++GO:0033993///response to lipid+++GO:0036316///SREBP-SCAP complex retention in endoplasmic reticulum+++GO:0042472///inner ear morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0060021///roof of mouth development+++GO:0060363///cranial suture morphogenesis+++GO:0070542///response to fatty acid 73010 73010 'Gpr22' mRNA 17 20 11 0.2 0.23 0.14 0.14 0.16 0.19 0.19 0.163333333 14 15 18 16 15.66666667 0.973369176 -0.031742031 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0042277///peptide binding GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030030///cell projection organization 73016 73016 'Kremen2' mRNA 7 9 9 0.19 0.24 0.26 0.19 0.12 0.02 0.23 0.11 8 5 1 8.333333333 4.666666667 0.48032198 -0.857392252 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030279///negative regulation of ossification+++GO:0060173///limb development 73024 73024 'Emc7' mRNA 1967 2083 1964 98.97 101.93 99.7 116.06 120.07 121.39 100.2 119.1733333 2545 2498 2501 2004.666667 2514.666667 3.55E-06 0.315324991 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0072546///ER membrane protein complex GO:0030246///carbohydrate binding+++GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 73046 73046 'Glrx5' mRNA 604 655 124 38.52 41.31 8.39 12.02 15.69 19.86 29.40666667 15.85666667 216 275 345 461 278.6666667 0.396276317 -0.705387228 GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0030425///dendrite+++GO:0043025///neuronal cell body "GO:0015035///protein disulfide oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0097573///glutathione oxidoreductase activity" GO:0030097///hemopoiesis+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0106034///protein maturation by [2Fe-2S] cluster transfer+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer 73047 73047 'Camk2n2' mRNA 8 5 3 0.38 0.23 0.15 0.16 0.21 0.04 0.253333333 0.136666667 4 5 1 5.333333333 3.333333333 0.663944105 -0.677704798 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0004860///protein kinase inhibitor activity+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding GO:0006469///negative regulation of protein kinase activity+++GO:0016310///phosphorylation+++GO:0043086///negative regulation of catalytic activity 73061 73061 'Cldn34c1' mRNA 66.76 89.26 72.07 1.07 1.45 1.23 1.62 1.09 1.65 1.25 1.453333333 114.1 76.91 113.65 76.03 101.5533333 0.19801956 0.404025741 GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0005198///structural molecule activity GO:0007155///cell adhesion+++GO:0070830///bicellular tight junction assembly 73062 73062 'Ppp1r16a' mRNA 2247 2385 1327 45.28 47.66 28.45 13.84 16.24 18.17 40.46333333 16.08333333 783 895 1000 1986.333333 892.6666667 1.11E-05 -1.151127472 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0008157///protein phosphatase 1 binding+++GO:0017020///myosin phosphatase regulator activity+++GO:0019888///protein phosphatase regulator activity GO:0035304///regulation of protein dephosphorylation+++GO:0050790///regulation of catalytic activity 73067 73067 'Tmem192' mRNA 607 579 397 33.65 32 23.44 27.95 40.02 35.66 29.69666667 34.54333333 577 804 711 527.6666667 697.3333333 0.013647835 0.401647453 GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0042803///protein homodimerization activity GO:0008150///biological_process 73068 73068 'Fut11' mRNA 633 636 578 10.32 10.2 10 11.17 11.07 10.77 10.17333333 11.00333333 788 763 736 615.6666667 762.3333333 0.004056248 0.29759756 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046920///alpha-(1->3)-fucosyltransferase activity" GO:0006486///protein glycosylation+++GO:0036065///fucosylation 73072 73072 'Prr36' mRNA 625 618 469 6.77 6.65 5.53 2.17 2.67 2.13 6.316666667 2.323333333 225 266 211 570.6666667 234 1.01E-18 -1.291293241 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73075 73075 'Ppil6' mRNA 434 426 455 24.02 23.5 26.47 5.24 5.56 5.89 24.66333333 5.563333333 108 115 121 438.3333333 114.6666667 7.87E-34 -1.947970187 GO:0005737///cytoplasm GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding 73078 73078 'Pmpcb' mRNA 1264 1212 1194 46.38 43.85 46.48 45.41 39.76 41.55 45.57 42.24 1422 1215 1259 1223.333333 1298.666667 0.489823094 0.073067052 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0017087///mitochondrial processing peptidase complex GO:0004175///endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006627///protein processing involved in protein targeting to mitochondrion+++GO:0016485///protein processing 73086 73086 'Rps6ka5' mRNA 228 224 141 2.14 2.07 1.41 0.79 0.73 0.85 1.873333333 0.79 96 87 101 197.6666667 94.66666667 3.67E-06 -1.065280298 04010///MAPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04713///Circadian entrainment+++04722///Neurotrophin signaling pathway+++05131///Shigellosis+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++05219///Bladder cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006468///protein phosphorylation+++GO:0006954///inflammatory response+++GO:0016310///phosphorylation+++GO:0016572///histone phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0033129///positive regulation of histone phosphorylation+++GO:0035066///positive regulation of histone acetylation+++GO:0035556///intracellular signal transduction+++GO:0043987///histone H3-S10 phosphorylation+++GO:0043988///histone H3-S28 phosphorylation+++GO:0043990///histone H2A-S1 phosphorylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070498///interleukin-1-mediated signaling pathway" 73094 73094 'Sgip1' mRNA 376 418 304 2.88 3.25 2.53 0.9 0.66 0.93 2.886666667 0.83 116 88 116 366 106.6666667 3.05E-23 -1.786447481 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030122///AP-2 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0098793///presynapse GO:0003676///nucleic acid binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008017///microtubule binding+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding GO:0002021///response to dietary excess+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0006508///proteolysis+++GO:0006897///endocytosis+++GO:0015074///DNA integration+++GO:0016032///viral process+++GO:0019068///virion assembly+++GO:0040018///positive regulation of multicellular organism growth+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048268///clathrin coat assembly+++GO:0072583///clathrin-dependent endocytosis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0097009///energy homeostasis+++GO:0097320///plasma membrane tubulation+++GO:1904000///positive regulation of eating behavior+++GO:2000253///positive regulation of feeding behavior 73095 73095 'Slc25a42' mRNA 857.74 753.1 619.37 14.8 12.78 11.33 6.4 5.99 5.18 12.97 5.856666667 426.89 390.06 334.82 743.4033333 383.9233333 2.00E-13 -0.96283991 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005347///ATP transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0015228///coenzyme A transmembrane transporter activity+++GO:0043262///adenosine-diphosphatase activity+++GO:0080122///AMP transmembrane transporter activity GO:0015866///ADP transport+++GO:0015867///ATP transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0055085///transmembrane transport+++GO:0080121///AMP transport 73102 73102 'Slc22a23' mRNA 390 440 422 4.1 4.48 4.64 2.91 2.56 2.51 4.406666667 2.66 318 279 273 417.3333333 290 1.60E-04 -0.538708458 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0055085///transmembrane transport 73103 73103 '3110009E18Rik' mRNA 95.03 67.01 84.02 7.04 4.41 9.01 4.85 5.69 6.01 6.82 5.516666667 93.03 119.68 114.01 82.02 108.9066667 0.189891497 0.394456791 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73106 73106 'Prss57' mRNA 111.18 114.63 73.36 4.07 4.45 2.76 2.23 2.25 3.78 3.76 2.753333333 73.51 76.01 119.44 99.72333333 89.65333333 0.689061634 -0.155205061 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0035578///azurophil granule lumen GO:0004252///serine-type endopeptidase activity+++GO:0008201///heparin binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 73112 73112 'Abracl' mRNA 139 101 117 11.95 8.67 10.73 50.47 54.09 45.47 10.45 50.01 678 705 586 119 656.3333333 2.37E-56 2.451429366 GO:0005575///cellular_component GO:0003674///molecular_function GO:0032970///regulation of actin filament-based process 73121 73121 'Rflna' mRNA 384 397 387 13.32 13.57 14.24 11.11 9.22 11.07 13.71 10.46666667 368 298 355 389.3333333 340.3333333 0.181090918 -0.207567377 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0032432///actin filament bundle GO:0031005///filamin binding GO:0048705///skeletal system morphogenesis+++GO:0061181///regulation of chondrocyte development+++GO:0061182///negative regulation of chondrocyte development+++GO:0061572///actin filament bundle organization+++GO:1900158///negative regulation of bone mineralization involved in bone maturation 73122 73122 'Tgfbrap1' mRNA 486 554 338 4.93 5.42 3.57 4.19 3.97 4.87 4.64 4.343333333 474 436 532 459.3333333 480.6666667 0.76697852 0.062506931 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005759///mitochondrial matrix+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0033263///CORVET complex+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0046332///SMAD binding+++GO:0051082///unfolded protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006457///protein folding+++GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0007165///signal transduction+++GO:0008333///endosome to lysosome transport+++GO:0009386///translational attenuation+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0034058///endosomal vesicle fusion+++GO:1901856///negative regulation of cellular respiration+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide" 73124 73124 'Golim4' mRNA 1110 1181 1061 13.18 13.81 13.36 12.25 11.16 11.02 13.45 11.47666667 1190 1060 1039 1117.333333 1096.333333 0.747324235 -0.038995633 GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0003674///molecular_function GO:0008150///biological_process 73130 73130 'Tmed5' mRNA 684.85 689.72 655.28 15.41 13.93 12.25 26 31.77 25.91 13.86333333 27.89333333 1525.24 1579.07 1550.06 676.6166667 1551.456667 1.85E-45 1.187550927 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0070971///endoplasmic reticulum exit site GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0090161///Golgi ribbon formation 73132 73132 'Slc25a16' mRNA 553 567 205 9.68 9.74 3.79 3.72 4.09 3.95 7.736666667 3.92 244 262 252 441.6666667 252.6666667 0.091328581 -0.79584687 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0055085///transmembrane transport 73137 73137 'Prrc1' mRNA 1265 1257 1213 14.06 13.7 14.26 16.56 15.74 15.44 14.00666667 15.91333333 1719 1597 1553 1245 1623 2.49E-06 0.370256916 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus GO:0034237///protein kinase A regulatory subunit binding+++GO:0042802///identical protein binding GO:0034199///activation of protein kinase A activity 73139 73139 'Cenpv' mRNA 85 50 70 5.18 2.95 4.44 2.48 1.61 2.62 4.19 2.236666667 47 30 48 68.33333333 41.66666667 0.060037653 -0.73105164 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030496///midbody+++GO:0031965///nuclear membrane+++GO:0051233///spindle midzone" GO:0003674///molecular_function+++GO:0016846///carbon-sulfur lyase activity+++GO:0046872///metal ion binding GO:0001667///ameboidal-type cell migration+++GO:0007049///cell cycle+++GO:0031508///pericentric heterochromatin assembly+++GO:0032467///positive regulation of cytokinesis+++GO:0033044///regulation of chromosome organization+++GO:0034508///centromere complex assembly+++GO:0051301///cell division 73149 73149 'Clec4a3' mRNA 108 117 116 5.29 5.9 6 51.65 47.01 46.27 5.73 48.31 1157 1037 1012 113.6666667 1068.666667 9.38E-140 3.220093561 GO:0005575///cellular_component+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004190///aspartic-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005537///mannose binding+++GO:0030246///carbohydrate binding "GO:0001818///negative regulation of cytokine production+++GO:0002470///plasmacytoid dendritic cell antigen processing and presentation+++GO:0006508///proteolysis+++GO:0006955///immune response+++GO:0008150///biological_process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0044419///interspecies interaction between organisms+++GO:0061760///antifungal innate immune response" 73158 73158 'Larp1' mRNA 942 894 896 7.61 7.12 7.71 9.06 7.4 8.29 7.48 8.25 1289 1025 1143 910.6666667 1152.333333 0.001261986 0.325555664 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:0031931///TORC1 complex+++GO:0042788///polysomal ribosome GO:0000339///RNA cap binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008190///eukaryotic initiation factor 4E binding+++GO:0008494///translation activator activity+++GO:0031369///translation initiation factor binding+++GO:0043024///ribosomal small subunit binding+++GO:0048027///mRNA 5'-UTR binding GO:0006413///translational initiation+++GO:0006417///regulation of translation+++GO:0008283///cell proliferation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016239///positive regulation of macroautophagy+++GO:0017148///negative regulation of translation+++GO:0031929///TOR signaling+++GO:0038202///TORC1 signaling+++GO:0045070///positive regulation of viral genome replication+++GO:0045727///positive regulation of translation+++GO:0045947///negative regulation of translational initiation+++GO:0045948///positive regulation of translational initiation+++GO:0048255///mRNA stabilization+++GO:0072752///cellular response to rapamycin+++GO:1990928///response to amino acid starvation 73162 73162 'Otud3' mRNA 201 216 147 2.72 2.61 1.38 1.07 0.47 0.61 2.236666667 0.716666667 78 60 59 188 65.66666667 1.37E-10 -1.524297899 GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0044313///protein K6-linked deubiquitination+++GO:0050821///protein stabilization+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0071108///protein K48-linked deubiquitination+++GO:1990167///protein K27-linked deubiquitination 73166 73166 'Tm7sf2' mRNA 934 962 935 37.4 37.99 39.72 14.43 15.76 14.77 38.37 14.98666667 414 441 410 943.6666667 421.6666667 6.15E-30 -1.173831052 00100///Steroid biosynthesis GO:0005637///nuclear inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex "GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0050613///delta14-sterol reductase activity+++GO:0050661///NADP binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016126///sterol biosynthetic process 73167 73167 'Arhgap8' mRNA 619 616 503 22.26 20.73 19.09 19.89 19.37 21.1 20.69333333 20.12 616 606 637 579.3333333 619.6666667 0.517713488 0.088998316 GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 73172 73172 'Exo5' mRNA 450 516 425 12.92 14.58 12.93 9.54 8.54 8.51 13.47666667 8.863333333 382 334 330 463.6666667 348.6666667 0.001792211 -0.421640916 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0006259///DNA metabolic process+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0036297///interstrand cross-link repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 73173 73173 'Pcdh18' mRNA 166 174 153 1.71 1.76 1.67 1.49 1.89 1.58 1.713333333 1.653333333 166 207 172 164.3333333 181.6666667 0.582341409 0.136352315 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development+++GO:0007420///brain development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 73174 73174 'Tbkbp1' mRNA 213 270 114 2.85 3.62 1.54 2.23 3.58 3.07 2.67 2.96 202 281 268 199 250.3333333 0.223706441 0.338015523 04622///RIG-I-like receptor signaling pathway GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response 73178 73178 'Wasl' mRNA 1348 1427 1192 24.65 24.42 20.71 19.42 17.84 16.93 23.26 18.06333333 1327 1186 1196 1322.333333 1236.333333 0.26468293 -0.106916319 04144///Endocytosis+++04520///Adherens junction+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0030027///lamellipodium+++GO:0030478///actin cap+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0042802///identical protein binding GO:0006900///vesicle budding from membrane+++GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0009617///response to bacterium+++GO:0010324///membrane invagination+++GO:0016050///vesicle organization+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0030048///actin filament-based movement+++GO:0030050///vesicle transport along actin filament+++GO:0031503///protein-containing complex localization+++GO:0032880///regulation of protein localization+++GO:0034629///cellular protein-containing complex localization+++GO:0045010///actin nucleation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050921///positive regulation of chemotaxis+++GO:0051301///cell division+++GO:0051491///positive regulation of filopodium assembly+++GO:0051653///spindle localization+++GO:0060491///regulation of cell projection assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0097320///plasma membrane tubulation+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1903526///negative regulation of membrane tubulation+++GO:2000370///positive regulation of clathrin-dependent endocytosis+++GO:2000402///negative regulation of lymphocyte migration+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 73181 73181 'Nfatc4' mRNA 429 434 326 5.91 5.88 4.83 4.15 3.96 4.81 5.54 4.306666667 343 311 383 396.3333333 345.6666667 0.218429703 -0.204134295 04022///cGMP-PKG signaling pathway+++04218///Cellular senescence+++04310///Wnt signaling pathway+++04360///Axon guidance+++04625///C-type lectin receptor signaling pathway+++04921///Oxytocin signaling pathway+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001816///cytokine production+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0007616///long-term memory+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0034644///cellular response to UV+++GO:0035562///negative regulation of chromatin binding+++GO:0043065///positive regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045333///cellular respiration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048167///regulation of synaptic plasticity+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0051145///smooth muscle cell differentiation+++GO:0055001///muscle cell development+++GO:0060291///long-term synaptic potentiation+++GO:0071285///cellular response to lithium ion+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1904637///cellular response to ionomycin+++GO:2000297///negative regulation of synapse maturation+++GO:2001235///positive regulation of apoptotic signaling pathway" 73182 73182 'Pear1' mRNA 1225 1258 1255 14.94 15.06 16.33 40.15 38.06 38.91 15.44333333 39.04 3789 3515 3559 1246 3621 1.96E-111 1.525972324 GO:0001891///phagocytic cup+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0043491///protein kinase B signaling+++GO:0043654///recognition of apoptotic cell+++GO:0070527///platelet aggregation 73192 73192 'Xpot' mRNA 1238 1185 1030 10.96 10.32 9.64 8.21 8.57 8.52 10.30666667 8.433333333 1071 1092 1072 1151 1078.333333 0.311516759 -0.102887681 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0031267///small GTPase binding GO:0006409///tRNA export from nucleus+++GO:0006886///intracellular protein transport+++GO:0071528///tRNA re-export from nucleus 73205 73205 'C9orf72' mRNA 1020 1020 990 17.63 17.38 18.21 11.36 10.78 9.97 17.74 10.70333333 756 699 642 1010 699 2.16E-08 -0.54360868 04140///Autophagy - animal+++05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0000932///P-body+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044295///axonal growth cone+++GO:0044304///main axon+++GO:0090543///Flemming body+++GO:1990316///Atg1/ULK1 kinase complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0001933///negative regulation of protein phosphorylation+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0016239///positive regulation of macroautophagy+++GO:0034063///stress granule assembly+++GO:0048675///axon extension+++GO:0050790///regulation of catalytic activity+++GO:0110053///regulation of actin filament organization+++GO:1902774///late endosome to lysosome transport+++GO:1903432///regulation of TORC1 signaling+++GO:1904425///negative regulation of GTP binding+++GO:2000785///regulation of autophagosome assembly 73212 73212 '3110082I17Rik' mRNA 424 385 411 17.16 15.37 17.54 18.65 15.35 16.52 16.69 16.84 529 428 464 406.6666667 473.6666667 0.160881697 0.205306637 GO:0005575///cellular_component GO:0008150///biological_process 73218 73218 'Sppl2b' mRNA 1987 2041 1894 39.31 39.87 39.97 21.11 18.14 20.99 39.71666667 20.08 1238 1021 1199 1974 1152.666667 3.87E-22 -0.788543012 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane "GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0042803///protein homodimerization activity" GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0050776///regulation of immune response 73225 73225 'Fam118a' mRNA 405.4 421.1 412 9.04 9.34 9.77 8.94 9.14 7.87 9.383333333 8.65 465.01 471.21 400 412.8333333 445.4066667 0.550080167 0.097602936 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0008150///biological_process 73229 73229 'Zfp983' mRNA 506.3 483.03 537.29 5.17 4.91 5.95 2.99 3.67 4.03 5.343333333 3.563333333 331.99 392.99 424.62 508.8733333 383.2 0.004158982 -0.424727941 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009617///response to bacterium+++GO:0045944///positive regulation of transcription by RNA polymerase II" 73230 73230 'Bmper' mRNA 189 212 231 2.69 2.97 3.48 0.37 0.47 0.55 3.046666667 0.463333333 30 37 43 210.6666667 36.66666667 1.98E-23 -2.536698533 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding GO:0001568///blood vessel development+++GO:0001657///ureteric bud development+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0010594///regulation of endothelial cell migration+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0042118///endothelial cell activation+++GO:0045765///regulation of angiogenesis+++GO:0048839///inner ear development+++GO:0060393///regulation of pathway-restricted SMAD protein phosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1903672///positive regulation of sprouting angiogenesis 73233 73233 'Zfp942' mRNA 309.4 283.69 296.9 5.2 4.73 5.34 4.17 4.15 3.6 5.09 3.973333333 279.87 274.83 233.33 296.6633333 262.6766667 0.296917021 -0.189042894 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73234 73234 'Snorc' mRNA 21 16 13 3.08 2.34 2.02 0 0.67 0.13 2.48 0.266666667 0 5 1 16.66666667 2 0.003224782 -3.054353159 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0071944///cell periphery GO:0005515///protein binding GO:0051216///cartilage development 73242 73242 'Atat1' mRNA 904 916 822 30.63 31.22 29.57 20.82 22.84 19.63 30.47333333 21.09666667 681 721 620 880.6666667 674 1.31E-04 -0.395690266 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005905///clathrin-coated pit+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0072686///mitotic spindle+++GO:0097427///microtubule bundle "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019799///tubulin N-acetyltransferase activity" GO:0007283///spermatogenesis+++GO:0021542///dentate gyrus development+++GO:0045598///regulation of fat cell differentiation+++GO:0048666///neuron development+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0071929///alpha-tubulin acetylation+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly 73246 73246 'Rassf6' mRNA 85 104 109 2.42 2.9 3.29 1.28 1.79 1.36 2.87 1.476666667 52 71 54 99.33333333 59 0.012205197 -0.76445599 04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species GO:0005575///cellular_component GO:0005515///protein binding GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process 73247 73247 'Mrgbp' mRNA 505 553 185 14.84 16.01 5.77 6.71 9.79 9.45 12.20666667 8.65 255 374 347 414.3333333 325.3333333 0.589609556 -0.33469856 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0043189///H4/H2A histone acetyltransferase complex GO:0003674///molecular_function "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth" 73251 73251 'Setd7' mRNA 342 386 357 2.45 2.72 2.71 2.76 2.46 2.96 2.626666667 2.726666667 444 386 460 361.6666667 430 0.106814786 0.237289523 00310///Lysine degradation+++04068///FoxO signaling pathway GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0002039///p53 binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006479///protein methylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0018022///peptidyl-lysine methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0045471///response to ethanol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051348///negative regulation of transferase activity+++GO:0051570///regulation of histone H3-K9 methylation+++GO:0070828///heterochromatin organization" 73254 73254 'Ccdc18' mRNA 108.14 119.64 107.31 1.64 1.77 1.74 1.74 1.22 1.5 1.716666667 1.486666667 129.31 87.92 108.65 111.6966667 108.6266667 0.863090843 -0.057637352 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73259 73259 'Cib4' mRNA 4 3 1 0.38 0.28 0.1 0 0 0 0.253333333 0 0 0 0 2.666666667 0 0.1442375 -3.849115089 GO:0005575///cellular_component GO:0000287///magnesium ion binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 73261 73261 '1700037C18Rik' mRNA 134 125 120 7.64 7.05 7.26 5.07 5.1 5.86 7.316666667 5.343333333 102 100 114 126.3333333 105.3333333 0.297553425 -0.273074548 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73274 73274 'Gpbp1' mRNA 1891.24 1893.57 1865.2 28.08 27.37 29.54 24.62 22.76 23.36 28.33 23.58 1897 1724.97 1739.7 1883.336667 1787.223333 0.300039194 -0.088755936 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 73284 73284 'Ddit4l' mRNA 517 498 516 10.51 9.97 11.13 9.03 8.8 8.93 10.53666667 8.92 511 486 489 510.3333333 495.3333333 0.726765945 -0.056211008 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0009968///negative regulation of signal transduction 73287 73287 'Cabcoco1' mRNA 609 584 639 29.06 27.43 31.92 8.12 9.54 9.91 29.47 9.19 197 224 233 610.6666667 218 1.66E-27 -1.499264425 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 73288 73288 'Vps50' mRNA 585 702.97 644 8.32 9.81 9.71 9.67 8.24 8.85 9.28 8.92 783 657.01 695 643.99 711.67 0.322715084 0.131486001 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome+++GO:1990745///EARP complex GO:0000149///SNARE binding "GO:0015031///protein transport+++GO:0032456///endocytic recycling+++GO:0042147///retrograde transport, endosome to Golgi" 73293 73293 'Ccdc103' mRNA 371 423 407 11.69 13.13 13.59 3.03 3.28 2.59 12.80333333 2.966666667 111 117 92 400.3333333 106.6666667 2.08E-29 -1.9207622 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036157///outer dynein arm+++GO:0042995///cell projection GO:0042803///protein homodimerization activity GO:0001947///heart looping+++GO:0003341///cilium movement+++GO:0003351///epithelial cilium movement+++GO:0007368///determination of left/right symmetry+++GO:0030030///cell projection organization+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0070286///axonemal dynein complex assembly+++GO:0071907///determination of digestive tract left/right asymmetry 73296 73296 'Rhobtb3' mRNA 770 785 798 8.53 8.55 9.52 6.87 5.99 7.11 8.866666667 6.656666667 708 599 714 784.3333333 673.6666667 0.044155671 -0.233507022 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding "GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0008584///male gonad development+++GO:0016192///vesicle-mediated transport+++GO:0016477///cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0042147///retrograde transport, endosome to Golgi" 73297 73297 '1700034I23Rik' mRNA 17 19 36 0.41 0.46 0.93 0.19 0.15 0.26 0.6 0.2 9 7 12 24 9.333333333 0.042223661 -1.392267397 GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane GO:0003674///molecular_function GO:0000422///autophagy of mitochondrion 73300 73300 '1700031F05Rik' mRNA 0 0 1 0 0 0.05 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73301 73301 'Ttc29' mRNA 1331 1426 1314 28.62 30.19 30.32 2.3 2.67 2.21 29.71 2.393333333 121 136 113 1357 123.3333333 1.41E-185 -3.470717009 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0044782///cilium organization 73314 73314 'Lrrc69' mRNA 165.73 146.93 162.15 0.77 0.67 0.79 1.75 1.93 1.95 0.743333333 1.876666667 435.91 470.95 470.05 158.27 458.97 4.49E-24 1.527329595 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007165///signal transduction 73316 73316 'Calr3' mRNA 57 52 70 2.17 1.79 2.64 1.76 2.9 2.15 2.2 2.27 54 88 66 59.66666667 69.33333333 0.639095842 0.202555639 GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response 73318 73318 'Ube2d2b' mRNA 17 31 24 0.61 1.11 0.92 0.5 0.13 0.13 0.88 0.253333333 16 4 4 24 8 0.030795879 -1.60702545 04013///MAPK signaling pathway - fly+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0035519///protein K29-linked ubiquitination+++GO:0044314///protein K27-linked ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0071276///cellular response to cadmium ion+++GO:0085020///protein K6-linked ubiquitination+++GO:1903841///cellular response to arsenite(3-) 73324 73324 'Clhc1' mRNA 2 4 2 0.06 0.11 0.06 0.22 0.22 0.05 0.076666667 0.163333333 9 9 2 2.666666667 6.666666667 0.339722939 1.316025634 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73327 73327 'Pradc1' mRNA 594.83 639.21 363.02 33.58 35.81 22.16 9.69 17.88 14.7 30.51666667 14.09 195.25 347.02 286.03 532.3533333 276.1 7.48E-06 -0.941819471 GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 73332 73332 'Ccdc30' mRNA 1180.68 1133.16 1112.64 19.74 18.43 19.19 4.4 4.34 4.68 19.12 4.473333333 302.21 283.17 294.79 1142.16 293.39 2.72E-83 -1.974309378 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73333 73333 'Slc25a31' mRNA 1 9 3 0.03 0.24 0.09 0.4 0.31 0.12 0.12 0.276666667 17 13 5 4.333333333 11.66666667 0.19494323 1.424974347 04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++04218///Cellular senescence+++04613///Neutrophil extracellular trap formation+++05010///Alzheimer disease+++05012///Parkinson disease+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05164///Influenza A+++05166///Human T-cell leukemia virus 1 infection+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005471///ATP:ADP antiporter activity+++GO:0015297///antiporter activity GO:0007141///male meiosis I+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0055085///transmembrane transport+++GO:0140021///mitochondrial ADP transmembrane transport+++GO:1990544///mitochondrial ATP transmembrane transport 73336 73336 'Prss44' mRNA 1 1 9 0.04 0.07 0.31 0 0.06 0 0.14 0.02 0 1 0 3.666666667 0.333333333 0.139914843 -3.418764314 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis 73338 73338 'Itpripl1' mRNA 385 312 371 5.82 4.88 6.16 16.16 16.53 15.81 5.62 16.16666667 1229 1210 1149 356 1196 4.72E-55 1.734194811 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 73340 73340 'Nptxr' mRNA 97.25 40.66 7.66 1.05 0.43 0.09 0.09 0.18 0.32 0.523333333 0.196666667 9.3 18.73 33.03 48.52333333 20.35333333 0.094871862 -1.240902788 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0043025///neuronal cell body+++GO:0098978///glutamatergic synapse GO:0008029///pentraxin receptor activity+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0031175///neuron projection development+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0099150///regulation of postsynaptic specialization assembly+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane 73341 73341 'Arhgef6' mRNA 740 814 723 8.96 9.8 9.33 13.49 13.15 13.12 9.363333333 13.25333333 1266 1224 1202 759 1230.666667 2.77E-15 0.686446125 04810///Regulation of actin cytoskeleton+++05212///Pancreatic cancer GO:0005911///cell-cell junction+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0030032///lamellipodium assembly+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 73344 73344 '1700034J05Rik' mRNA 3 4 2 0.09 0.11 0.06 0.23 0.25 0.27 0.086666667 0.25 10 10 11 3 10.33333333 0.091453507 1.780810947 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73363 73363 '1700056E22Rik' mRNA 26 11 21 1.73 0.73 1.49 0.76 1.19 0.48 1.316666667 0.81 13 20 8 19.33333333 13.66666667 0.518785108 -0.515115502 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73368 73368 'Col20a1' mRNA 182 124 142 2.04 1.37 1.53 0.97 0.76 0.76 1.646666667 0.83 115 95 88 149.3333333 99.33333333 0.01753915 -0.601926413 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix 73373 73373 'Phospho2' mRNA 584 590 639 16.09 15.94 18.63 17 14.92 14.19 16.88666667 15.37 715 607 577 604.3333333 633 0.757394825 0.050847737 00750///Vitamin B6 metabolism+++01240///Biosynthesis of cofactors GO:0005575///cellular_component GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0033883///pyridoxal phosphatase activity+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 73376 73376 'Tex33' mRNA 316 350 351 20.4 22.65 24.14 2.16 1.42 2.68 22.39666667 2.086666667 37 26 43 339 35.33333333 3.26E-48 -3.276749549 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73379 73379 'Dcbld2' mRNA 728 679 664 6.05 5.65 5.79 5.9 4.83 5.8 5.83 5.51 795 634 774 690.3333333 734.3333333 0.593786461 0.076170367 GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030308///negative regulation of cell growth+++GO:0042060///wound healing 73381 73381 'Cmtm2a' mRNA 7 12 15 0.41 0.69 0.92 1.21 0.88 0.99 0.673333333 1.026666667 24 17 19 11.33333333 20 0.268393662 0.796535647 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003714///transcription corepressor activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008009///chemokine activity "GO:0006935///chemotaxis+++GO:0007165///signal transduction+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0032940///secretion by cell+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis+++GO:2000224///regulation of testosterone biosynthetic process" 73385 73385 'Fam177a' mRNA 757.94 1440.86 752.8 10.61 19.84 11.18 10.72 0.25 10.81 13.87666667 7.26 881.73 19.96 860.77 983.8666667 587.4866667 0.653863948 -0.758476615 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73389 73389 'Hbp1' mRNA 3046.49 3344.84 3337.55 62.08 67.21 72.05 55.36 56.34 53.53 67.11333333 55.07666667 3119.44 3068.16 2908 3242.96 3031.866667 0.18615318 -0.11054007 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0032369///negative regulation of lipid transport+++GO:0043268///positive regulation of potassium ion transport+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process" 73390 73390 'Msl3l2' mRNA 166 172 30 4.39 4.45 0.84 0.76 0.92 0.88 3.226666667 0.853333333 33 39 37 122.6666667 36.33333333 1.67E-04 -1.737202521 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0072487///MSL complex GO:0003677///DNA binding+++GO:0035064///methylated histone binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific) "GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016573///histone acetylation+++GO:0016575///histone deacetylation+++GO:0031507///heterochromatin assembly+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0043984///histone H4-K16 acetylation" 73407 73407 'Tepp' mRNA 285.62 320.48 232.84 4.14 4.47 3.66 3.03 3.19 3.06 4.09 3.093333333 223.74 216.28 203.82 279.6466667 214.6133333 0.026587415 -0.389530649 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73410 73410 '1700065D16Rik' mRNA 0 2 1 0 0.32 0.17 0 0 0 0.163333333 0 0 0 0 1 0 0.607488248 -2.448949589 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73419 73419 'Armt1' mRNA 324 344 362 7.93 8.28 9.32 8.64 8.08 8.51 8.51 8.41 409 374 391 343.3333333 391.3333333 0.27074957 0.174278322 GO:0005575///cellular_component GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0008983///protein-glutamate O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0051998///protein carboxyl O-methyltransferase activity+++GO:0097023///fructose 6-phosphate aldolase activity+++GO:0103026///fructose-1-phosphatase activity GO:0006479///protein methylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016311///dephosphorylation+++GO:0032259///methylation+++GO:2001020///regulation of response to DNA damage stimulus 73420 73420 'Ccsap' mRNA 29 31 20 0.59 0.61 0.43 0.4 0.51 0.48 0.543333333 0.463333333 23 29 29 26.66666667 27 0.98714719 0.015365467 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030424///axon+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0061673///mitotic spindle astral microtubule+++GO:0072686///mitotic spindle GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0045995///regulation of embryonic development+++GO:0051301///cell division+++GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:1901673///regulation of mitotic spindle assembly+++GO:1990755///mitotic spindle microtubule depolymerization 73422 73422 'Prox2' mRNA 168.42 187.01 198.67 1.91 2.03 2.32 1.24 1.25 1.37 2.086666667 1.286666667 134.46 117.97 138.2 184.7 130.21 0.014553006 -0.522735064 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73430 73430 'Zfp974' mRNA 380.22 322.73 348.25 2.51 2.14 2.49 1.48 1.38 1.63 2.38 1.496666667 252.39 233.15 268.2 350.4 251.2466667 0.001720144 -0.492695649 05168///Herpes simplex virus 1 infection GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II" 73435 73435 'Tex35' mRNA 14 10 4 0.5 0.42 0.23 0.15 0.1 0.08 0.383333333 0.11 2 2 1 9.333333333 1.666666667 0.047394748 -2.480395706 GO:0005634///nucleus+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 73442 73442 'Hspa12a' mRNA 1386.61 1528.32 1496.37 12.75 13.81 14.61 11.43 10.25 10.68 13.72333333 10.78666667 1422.52 1245 1280 1470.433333 1315.84 0.065287389 -0.174039531 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0008150///biological_process 73447 73447 'Wdr13' mRNA 1383 1468 1414 18.84 19.61 20.41 11.41 10.71 10.77 19.62 10.96333333 973 877 873 1421.666667 907.6666667 1.03E-14 -0.660380914 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0034451///centriolar satellite GO:1990841///promoter-specific chromatin binding GO:1904691///negative regulation of type B pancreatic cell proliferation 73449 73449 '1700066B19Rik' mRNA 0 8 4 0 0.18 0.09 0.27 0.32 0.28 0.09 0.29 14 16 14 4 14.66666667 0.059390468 1.868154071 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 73451 73451 'Zfp763' mRNA 348 383 371 5.6 6.07 6.34 3.69 2.85 3.24 6.003333333 3.26 264 199 224 367.3333333 229 9.38E-06 -0.696395214 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73453 73453 '1700067K01Rik' mRNA 9 9 6 0.27 0.31 0.24 0.12 0.12 0.2 0.273333333 0.146666667 4 3 9 8 5.333333333 0.63082596 -0.588853839 GO:0005575///cellular_component GO:0003674///molecular_function GO:0001701///in utero embryonic development 73456 73456 'Izumo1' mRNA 1 6 1 0.06 0.32 0.07 0.14 0.06 0.12 0.15 0.106666667 3 1 3 2.666666667 2.333333333 0.92978346 -0.185949631 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0034113///heterotypic cell-cell adhesion+++GO:0035036///sperm-egg recognition 73458 73458 'Aldh3b3' mRNA 14.36 17.28 26.74 0.57 0.68 1.14 0.89 0.59 0.81 0.796666667 0.763333333 25.68 16.61 22.72 19.46 21.67 0.869540119 0.118241792 00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00410///beta-Alanine metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane "GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0043878///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity" GO:0006081///cellular aldehyde metabolic process 73463 73463 'C2cd6' mRNA 4 3 0 0.07 0.03 0 0 0 0 0.033333333 0 0 0 0 2.333333333 0 0.236361545 -3.642213188 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73466 73466 'Ms4a13' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 73467 73467 '1700066M21Rik' mRNA 172 152 164 3.23 2.82 3.28 3.86 4.03 3.28 3.11 3.723333333 233 243 195 162.6666667 223.6666667 0.02405672 0.446657493 GO:0005576///extracellular region+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0006119///oxidative phosphorylation 73469 73469 'Rnf38' mRNA 684 663 570 7.49 7.09 6.62 6.73 6.26 6.55 7.066666667 6.513333333 711 643 672 639 675.3333333 0.603400535 0.070045198 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0036126///sperm flagellum GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008584///male gonad development+++GO:0016567///protein ubiquitination 73472 73472 'Spata18' mRNA 1 3 3 0.03 0.09 0.1 0.11 0.16 0.11 0.073333333 0.126666667 4 6 4 2.333333333 4.666666667 0.537288807 0.98564459 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0036126///sperm flagellum+++GO:0043231///intracellular membrane-bounded organelle GO:0042802///identical protein binding GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0035694///mitochondrial protein catabolic process+++GO:0035695///mitophagy by induced vacuole formation 73473 73473 'Iws1' mRNA 1037.75 1083.8 985.54 10.68 10.78 11.32 11.53 10.24 10.66 10.92666667 10.81 1225.19 1024.72 1125.87 1035.696667 1125.26 0.300547359 0.107759083 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0010793///regulation of mRNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0050684///regulation of mRNA processing+++GO:0051028///mRNA transport+++GO:0090239///regulation of histone H4 acetylation+++GO:2001253///regulation of histone H3-K36 trimethylation 73490 73490 'Mipol1' mRNA 195.15 172 171 7.97 6.93 7.41 3.6 3.75 3.34 7.436666667 3.563333333 101.12 102.97 90.92 179.3833333 98.33666667 3.25E-05 -0.88804734 GO:0005634///nucleus GO:0042802///identical protein binding GO:0008150///biological_process 73503 73503 'Mbd3l1' mRNA 1 0 0 0.08 0 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus GO:0008327///methyl-CpG binding GO:0000122///negative regulation of transcription by RNA polymerase II 73523 73523 'Pebp4' mRNA 55 39 39 3.2 2.21 2.37 0.54 1.13 1.53 2.593333333 1.066666667 9 22 28 44.33333333 19.66666667 0.022405042 -1.176161398 GO:0005576///extracellular region+++GO:0005764///lysosome GO:0008150///biological_process 73526 73526 'Speer4b' mRNA 14.49 0.95 4.77 0.42 0.03 0.15 0 0.03 0.05 0.2 0.026666667 0 1 1.99 6.736666667 0.996666667 0.106764375 -3.169905477 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73545 73545 '1700094D03Rik' mRNA 1093.33 1160.2 1226 19.43 20.29 23.11 3.43 3.31 3.45 20.94333333 3.396666667 221.98 209.47 216.44 1159.843333 215.9633333 2.12E-97 -2.443906191 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73569 73569 'Vgll3' mRNA 184 190 141 1.38 1.41 1.12 1.62 1.26 1.67 1.303333333 1.516666667 248 189 249 171.6666667 228.6666667 0.046572639 0.405215006 GO:0005634///nucleus GO:0008022///protein C-terminus binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73582 73582 'Camkmt' mRNA 473.3 509.3 431.93 11.34 12.25 11.02 4.9 4.35 4.21 11.53666667 4.486666667 302.18 254.9 276.08 471.51 277.72 6.08E-09 -0.774720038 00310///Lysine degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0018025///calmodulin-lysine N-methyltransferase activity+++GO:0031072///heat shock protein binding GO:0007005///mitochondrion organization+++GO:0018022///peptidyl-lysine methylation+++GO:0032259///methylation 73598 73598 '1700001O22Rik' mRNA 126 124 111 5.25 5.13 4.93 5.56 4.94 4.92 5.103333333 5.14 152 130 127 120.3333333 136.3333333 0.529762717 0.168761652 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73603 73603 'Trp53tg5' mRNA 36 18 22 0.76 0.37 0.49 0.41 0.38 0.19 0.54 0.326666667 22.51 20.31 10 25.33333333 17.60666667 0.405492996 -0.559626882 GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003674///molecular_function GO:0008150///biological_process 73608 73608 'Marveld3' mRNA 1496 1487 1499 40.14 39.36 42.5 21.4 21.42 22.73 40.66666667 21.85 909 886 916 1494 903.6666667 7.19E-19 -0.738056687 04530///Tight junction GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle GO:0031435///mitogen-activated protein kinase kinase kinase binding GO:0006970///response to osmotic stress+++GO:0010633///negative regulation of epithelial cell migration+++GO:0045216///cell-cell junction organization+++GO:0046329///negative regulation of JNK cascade+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0070830///bicellular tight junction assembly+++GO:1902414///protein localization to cell junction 73610 73610 'Zfp433' mRNA 416.85 503.25 442.84 7.89 9.59 8.95 4.92 4.07 5.14 8.81 4.71 291.25 227.68 285.7 454.3133333 268.21 1.58E-07 -0.773812386 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73634 73634 '1700125H20Rik' mRNA 3.09 5.72 5.42 0.05 0.31 0.09 0.05 0.09 0.13 0.15 0.09 3.83 1 4 4.743333333 2.943333333 0.669862772 -0.720141097 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73635 73635 'Ptges3l' mRNA 75.56 58.65 84.12 3.3 2.57 3.99 5.67 7.43 4.91 3.286666667 6.003333333 143.95 188.81 125.79 72.77666667 152.85 1.11E-04 1.055798029 GO:0005634///nucleus+++GO:0005829///cytosol GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly 73647 73647 'Capn9' mRNA 2 1 2 0.05 0.02 0.05 0 0.04 0.04 0.04 0.026666667 0 2 3 1.666666667 1.666666667 0.998591786 -0.008511962 GO:0005737///cytoplasm GO:0004198///calcium-dependent cysteine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0007586///digestion 73649 73649 'Cybrd1' mRNA 638.03 594.3 492.77 6.53 5.98 5.35 2.88 3.15 3.06 5.953333333 3.03 324.01 345.58 333.37 575.0333333 334.32 6.40E-10 -0.790150689 04978///Mineral absorption GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane "GO:0000293///ferric-chelate reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding" GO:0006879///cellular iron ion homeostasis+++GO:0010039///response to iron ion+++GO:0055072///iron ion homeostasis+++GO:0055085///transmembrane transport 73656 73656 'Ms4a6c' mRNA 152.36 163.84 149.37 7.01 7.23 8.51 148.99 149.24 147.23 7.583333333 148.4866667 2795.92 2649.97 2703.32 155.19 2716.403333 0 4.122966601 GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane 73658 73658 'Spns1' mRNA 1355 1377 1259 27.42 27.56 27.02 27.74 27.96 26.5 27.33333333 27.4 1573 1547 1455 1330.333333 1525 0.022795683 0.1862388 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane GO:0003677///DNA binding+++GO:0022857///transmembrane transporter activity+++GO:0035064///methylated histone binding "GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006869///lipid transport+++GO:0007049///cell cycle+++GO:0007143///female meiotic nuclear division+++GO:0007276///gamete generation+++GO:0009303///rRNA transcription+++GO:0016055///Wnt signaling pathway+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051321///meiotic cell cycle+++GO:0055085///transmembrane transport" 73660 73660 'Cabp4' mRNA 9 15 4 0.37 0.6 0.18 0.18 0.11 0.21 0.383333333 0.166666667 5 3 6 9.333333333 4.666666667 0.378411269 -0.993920513 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098793///presynapse GO:0005246///calcium channel regulator activity+++GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0008594///photoreceptor cell morphogenesis+++GO:0046549///retinal cone cell development+++GO:0060040///retinal bipolar neuron differentiation 73666 73666 'Thoc3' mRNA 812 903 778 19.58 21.44 19.9 21.57 22.56 21.78 20.30666667 21.97 1029 1051 1006 831 1028.666667 0.001663072 0.298063594 03013///Nucleocytoplasmic transport+++03040///Spliceosome "GO:0000346///transcription export complex+++GO:0000445///THO complex part of transcription export complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0016607///nuclear speck" GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport 73667 73667 '2410004P03Rik' mRNA 1565.21 1572 1603 54.25 53.54 59.55 3.76 3.31 3.17 55.78 3.413333333 123 104.18 101.6 1580.07 109.5933333 7.25E-223 -3.867164204 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73668 73668 'Ttc21b' mRNA 182 229 193 2.17 2.7 2.44 2.13 2.29 2.7 2.436666667 2.373333333 205 216 252 201.3333333 224.3333333 0.516282515 0.146539476 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030991///intraciliary transport particle A+++GO:0042995///cell projection GO:0003682///chromatin binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007224///smoothened signaling pathway+++GO:0008589///regulation of smoothened signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0021549///cerebellum development+++GO:0021591///ventricular system development+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0030900///forebrain development+++GO:0035721///intraciliary retrograde transport+++GO:0060020///Bergmann glial cell differentiation+++GO:0061512///protein localization to cilium+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0097499///protein localization to non-motile cilium+++GO:1903999///negative regulation of eating behavior+++GO:1905799///regulation of intraciliary retrograde transport 73670 73670 'Defb30' mRNA 1 2 2 0.06 0.13 0.14 0 0 0.06 0.11 0.02 0 0 1 1.666666667 0.333333333 0.461402549 -2.235284209 GO:0005576///extracellular region GO:0003674///molecular_function GO:0006952///defense response+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response 73671 73671 'Sult6b1' mRNA 3 1 0 0.17 0.07 0 0 0.12 0 0.08 0.04 0 2 0 1.333333333 0.666666667 0.79773979 -0.963907923 GO:0005737///cytoplasm GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity GO:0051923///sulfation 73673 73673 'Rec114' mRNA 35 49 41 1.48 1.72 1.48 1.33 0.97 1.19 1.56 1.163333333 46 29 41 41.66666667 38.66666667 0.829757192 -0.121806003 GO:0005575///cellular_component GO:0005515///protein binding GO:0006310///DNA recombination+++GO:0008150///biological_process+++GO:0051321///meiotic cell cycle 73674 73674 'Wdr75' mRNA 331 368 380 6.12 6.7 7.46 8.57 7.57 7.75 6.76 7.963333333 533 460 467 359.6666667 486.6666667 0.002339943 0.421160566 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:2000234///positive regulation of rRNA processing 73677 73677 'Psma8' mRNA 10 8 3 0.52 0.5 0.22 1.06 1.23 1.57 0.413333333 1.286666667 25 28 27 7 26.66666667 0.003696291 1.931263047 03050///Proteasome+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:1990111///spermatoproteasome complex" GO:0004175///endopeptidase activity+++GO:0005515///protein binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0030154///cell differentiation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051321///meiotic cell cycle+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060631///regulation of meiosis I 73679 73679 'Tex19.1' mRNA 1 0 0 0.03 0 0 0.06 0.03 0.09 0.01 0.06 2 1 3 0.333333333 2 0.383181992 2.466605927 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0034584///piRNA binding GO:0001701///in utero embryonic development+++GO:0001890///placenta development+++GO:0007129///synapsis+++GO:0007131///reciprocal meiotic recombination+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0010529///negative regulation of transposition+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0019953///sexual reproduction+++GO:0030154///cell differentiation+++GO:0051321///meiotic cell cycle+++GO:0060720///spongiotrophoblast cell proliferation+++GO:0060722///cell proliferation involved in embryonic placenta development 73680 73680 'Zbtb8a' mRNA 177.14 161 181.7 4.47 4 4.87 5.63 4.41 5.61 4.446666667 5.216666667 256.5 196 247.05 173.28 233.1833333 0.036830981 0.413748495 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process 73681 73681 'Trmt11' mRNA 245 260 250 5.95 6.08 6.4 5.7 5.79 5.76 6.143333333 5.75 266 267 266 251.6666667 266.3333333 0.742736494 0.069906354 GO:0005737///cytoplasm GO:0000049///tRNA binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004809///tRNA (guanine-N2-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 73683 73683 'Atg16l2' mRNA 441 400 382 8.91 7.99 8.62 9.02 9.05 8.49 8.506666667 8.853333333 500 446 445 407.6666667 463.6666667 0.219672489 0.174096513 04140///Autophagy - animal GO:0000421///autophagosome membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol GO:0005515///protein binding GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0039689///negative stranded viral RNA replication 73689 73689 'Bloc1s2' mRNA 589.4 533.95 614.07 33.31 32.12 35.15 51.35 49.11 47.71 33.52666667 49.39 1223.95 1161.76 1116.18 579.14 1167.296667 4.86E-22 0.99653387 GO:0000930///gamma-tubulin complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0031083///BLOC-1 complex+++GO:0055037///recycling endosome+++GO:0099078///BORC complex+++GO:1904115///axon cytoplasm GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0043015///gamma-tubulin binding "GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006886///intracellular protein transport+++GO:0007219///Notch signaling pathway+++GO:0008089///anterograde axonal transport+++GO:0008284///positive regulation of cell proliferation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0016197///endosomal transport+++GO:0021895///cerebral cortex neuron differentiation+++GO:0021987///cerebral cortex development+++GO:0031175///neuron projection development+++GO:0032418///lysosome localization+++GO:0035162///embryonic hemopoiesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048490///anterograde synaptic vesicle transport+++GO:0061351///neural precursor cell proliferation+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:1905146///lysosomal protein catabolic process+++GO:1990403///embryonic brain development" 73690 73690 'Glipr1' mRNA 11.79 14.52 22.81 0.68 0.78 1.41 19.11 23.02 19.45 0.956666667 20.52666667 381.16 445.89 373.18 16.37333333 400.0766667 5.84E-65 4.659611097 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane 73692 73692 'Cplane1' mRNA 834 740 722 4.15 3.6 3.83 2.65 2.31 2.43 3.86 2.463333333 613 521 544 765.3333333 559.3333333 2.75E-05 -0.464609179 GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection GO:0005515///protein binding GO:0001736///establishment of planar polarity+++GO:0001822///kidney development+++GO:0003279///cardiac septum development+++GO:0003281///ventricular septum development+++GO:0007507///heart development+++GO:0021549///cerebellum development+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0060021///roof of mouth development+++GO:0060271///cilium assembly+++GO:0060976///coronary vasculature development+++GO:1904491///protein localization to ciliary transition zone 73694 73694 'Ndufaf7' mRNA 718.94 800.93 703.74 17.72 19.36 18.35 13.17 13.78 13.21 18.47666667 13.38666667 616.09 629.72 599.72 741.2033333 615.1766667 0.010085657 -0.278627947 04714///Thermogenesis GO:0005739///mitochondrion GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity "GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0032259///methylation+++GO:0032981///mitochondrial respiratory chain complex I assembly" 73699 73699 'Ppp2r1b' mRNA 822.98 863.65 859.74 12.26 12.65 13.59 12.49 13.22 11.65 12.83333333 12.45333333 959.55 995.86 868.41 848.79 941.2733333 0.23012704 0.137064096 03015///mRNA surveillance pathway+++04071///Sphingolipid signaling pathway+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04350///TGF-beta signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++04728///Dopaminergic synapse+++04730///Long-term depression+++05142///Chagas disease+++05160///Hepatitis C+++05165///Human papillomavirus infection GO:0000159///protein phosphatase type 2A complex+++GO:0005737///cytoplasm+++GO:0008287///protein serine/threonine phosphatase complex+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity GO:0006470///protein dephosphorylation+++GO:0050790///regulation of catalytic activity+++GO:0060561///apoptotic process involved in morphogenesis+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 73703 73703 'Dppa2' mRNA 1 2 3 0.03 0.06 0.09 0 0 0.11 0.06 0.036666667 0 0 4 2 1.333333333 0.8374159 -0.606663451 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003682///chromatin binding GO:0019827///stem cell population maintenance+++GO:0031060///regulation of histone methylation+++GO:0048731///system development+++GO:0060484///lung-associated mesenchyme development+++GO:2000648///positive regulation of stem cell proliferation 73707 73707 'Gucy2g' mRNA 1 2 5 0.01 0.03 0.08 0 0.04 0 0.04 0.013333333 0 3 0 2.666666667 1 0.563446406 -1.438464232 00230///Purine metabolism GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0001653///peptide receptor activity+++GO:0004383///guanylate cyclase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016849///phosphorus-oxygen lyase activity GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0035556///intracellular signal transduction 73708 73708 'Dppa3' mRNA 5 0 0 0.41 0 0 0.65 1.04 0.52 0.136666667 0.736666667 9 14 7 1.666666667 10 0.054914155 2.592560322 GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0035064///methylated histone binding GO:0006325///chromatin organization+++GO:0007275///multicellular organism development+++GO:0040016///embryonic cleavage+++GO:0044726///protection of DNA demethylation of female pronucleus+++GO:1901536///negative regulation of DNA demethylation+++GO:2000653///regulation of genetic imprinting 73710 73710 'Tubb2b' mRNA 398.77 470.71 314.4 11.87 13.8 9.92 8.7 5.38 6.85 11.86333333 6.976666667 336.18 202.84 256.31 394.6266667 265.11 0.002084032 -0.5830078 04145///Phagosome+++04540///Gap junction+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0098685///Schaffer collateral - CA1 synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding+++GO:0046982///protein heterodimerization activity GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0001764///neuron migration+++GO:0007010///cytoskeleton organization+++GO:0007017///microtubule-based process+++GO:0007399///nervous system development+++GO:0050804///modulation of chemical synaptic transmission+++GO:1902669///positive regulation of axon guidance+++GO:1990403///embryonic brain development 73711 73711 'Mvb12a' mRNA 1460 1435 1422 85.62 83.59 88.86 113.64 117.9 112.14 86.02333333 114.56 2213 2237 2109 1439 2186.333333 8.31E-16 0.591455501 04144///Endocytosis GO:0000813///ESCRT I complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0031982///vesicle GO:0008289///lipid binding+++GO:0017124///SH3 domain binding+++GO:0043130///ubiquitin binding GO:0015031///protein transport+++GO:0019075///virus maturation+++GO:0032510///endosome to lysosome transport via multivesicular body sorting pathway+++GO:0032801///receptor catabolic process+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0046755///viral budding 73712 73712 'Dmkn' mRNA 51 32 41 2.97 1.65 2.58 1.49 1.94 2.32 2.4 1.916666667 20 25 24 41.33333333 23 0.071293343 -0.857443235 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0030154///cell differentiation+++GO:1903575///cornified envelope assembly 73713 73713 'Rbm20' mRNA 289 293 310 2.09 2.1 2.41 1.08 0.97 0.89 2.2 0.98 177 149 136 297.3333333 154 3.90E-08 -0.964572001 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding GO:0006397///mRNA processing+++GO:0007507///heart development+++GO:0008380///RNA splicing+++GO:0033120///positive regulation of RNA splicing+++GO:0043484///regulation of RNA splicing 73719 73719 'Lce1c' mRNA 1 0 0 0.1 0 0 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process+++GO:0008544///epidermis development+++GO:0031424///keratinization 73720 73720 'Cst6' mRNA 635 625 686 8.68 8.4 9.95 25.24 28.74 26.33 9.01 26.77 2125 2364 2147 648.6666667 2212 6.93E-79 1.756680693 GO:0001533///cornified envelope GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0008544///epidermis development+++GO:0010951///negative regulation of endopeptidase activity 73721 73721 '1110017D15Rik' mRNA 1642 1597 1822 222.18 215.95 266.04 19.7 24.18 23.9 234.7233333 22.59333333 170 186 189 1687 181.6666667 7.27E-164 -3.230314167 GO:0002177///manchette+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0043014///alpha-tubulin binding GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0034622///cellular protein-containing complex assembly 73723 73723 'Sh3bgrl3' mRNA 1681 1717 1612 176.17 178.74 179.3 613.76 634.06 595.19 178.07 614.3366667 6693 6727 6261 1670 6560.333333 1.65E-231 1.962771805 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body GO:0015035///protein disulfide oxidoreductase activity 73724 73724 'Mcee' mRNA 731 734 713 61.08 61.23 63.73 56.2 60.22 59.75 62.01333333 58.72333333 757 788 779 726 774.6666667 0.500299442 0.082259281 "00280///Valine, leucine and isoleucine degradation+++00630///Glyoxylate and dicarboxylate metabolism+++00640///Propanoate metabolism+++01200///Carbon metabolism" GO:0005739///mitochondrion GO:0004493///methylmalonyl-CoA epimerase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding GO:0046491///L-methylmalonyl-CoA metabolic process 73728 73728 'Psd' mRNA 43.79 40.41 39.46 0.58 0.54 0.56 0.6 0.35 0.4 0.56 0.45 36.18 25.5 26.07 41.22 29.25 0.289723776 -0.501988599 04144///Endocytosis+++04361///Axon regeneration "GO:0001726///ruffle+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0098999///extrinsic component of postsynaptic endosome membrane+++GO:0099092///postsynaptic density, intracellular component" GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding GO:0031175///neuron projection development+++GO:0032012///regulation of ARF protein signal transduction+++GO:0050790///regulation of catalytic activity 73729 73729 'Zfp383' mRNA 66 68 43 1.4 1.42 0.95 0.75 0.75 0.73 1.256666667 0.743333333 41 40 39 59 40 0.147419086 -0.564520068 05168///Herpes simplex virus 1 infection GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 73736 73736 'Fcf1' mRNA 617 557 558 61.05 54.71 58.59 83.16 82.79 80.09 58.11666667 82.01333333 961 931 893 577.3333333 928.3333333 1.42E-11 0.673405607 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome "GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis" 73737 73737 '1110008P14Rik' mRNA 753 778 694 84.06 86.34 82.23 105.26 107.63 115.95 84.21 109.6133333 1077 1071 1144 741.6666667 1097.333333 9.22E-10 0.555134809 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73738 73738 'Haus7' mRNA 626 634 515 28.36 28.79 24.83 20.61 19.78 20.42 27.32666667 20.27 520 484 497 591.6666667 500.3333333 0.039142861 -0.250531547 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function+++GO:0031996///thioesterase binding+++GO:0051011///microtubule minus-end binding GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 73739 73739 'Cby1' mRNA 711 716 721 39.59 39.39 42.68 31.26 31.9 32.77 40.55333333 31.97666667 643 638 652 716 644.3333333 0.151724598 -0.164699996 04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity "GO:0008104///protein localization+++GO:0030030///cell projection organization+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0033504///floor plate development+++GO:0045444///fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051289///protein homotetramerization+++GO:0055007///cardiac muscle cell differentiation+++GO:0060271///cilium assembly+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 73744 73744 'Man2c1' mRNA 1472 1651 1296 23.61 26.45 22.48 19.42 17.87 17.58 24.18 18.29 1330 1210 1179 1473 1239.666667 0.00472983 -0.25760331 00511///Other glycan degradation GO:0005654///nucleoplasm+++GO:0005737///cytoplasm "GO:0003824///catalytic activity+++GO:0004559///alpha-mannosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006013///mannose metabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process 73747 73747 'Shld1' mRNA 393 446 415 18.63 21.13 22.78 18.03 17.93 17.94 20.84666667 17.96666667 359 348 353 418 353.3333333 0.073188633 -0.254417699 GO:0005694///chromosome+++GO:0035861///site of double-strand break GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045830///positive regulation of isotype switching+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 73748 73748 'Gadl1' mRNA 2 1 0 0.05 0.01 0 0.05 0.02 0.05 0.02 0.04 2 1 1 1 1.333333333 0.881865408 0.422292456 00410///beta-Alanine metabolism+++00430///Taurine and hypotaurine metabolism+++00770///Pantothenate and CoA biosynthesis GO:0005575///cellular_component GO:0003824///catalytic activity+++GO:0004068///aspartate 1-decarboxylase activity+++GO:0004782///sulfinoalanine decarboxylase activity+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding GO:0008150///biological_process+++GO:0019752///carboxylic acid metabolic process 73750 73750 'Whrn' mRNA 333 270 185 4.43 3.55 2.68 0.8 0.91 1.03 3.553333333 0.913333333 70 74 82 262.6666667 75.33333333 4.13E-15 -1.803930583 GO:0001917///photoreceptor inner segment+++GO:0002141///stereocilia ankle link+++GO:0002142///stereocilia ankle link complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030426///growth cone+++GO:0032391///photoreceptor connecting cilium+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032426///stereocilium tip+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0044303///axon collateral+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0097440///apical dendrite+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:1990075///periciliary membrane compartment+++GO:1990696///USH2 complex GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0042802///identical protein binding GO:0001895///retina homeostasis+++GO:0007605///sensory perception of sound+++GO:0010628///positive regulation of gene expression+++GO:0021694///cerebellar Purkinje cell layer formation+++GO:0045184///establishment of protein localization+++GO:0050910///detection of mechanical stimulus involved in sensory perception of sound+++GO:0050953///sensory perception of light stimulus+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:1990227///paranodal junction maintenance 73754 73754 'Thap1' mRNA 204 261 193 5.06 6.37 5.08 4.55 5.39 5.08 5.503333333 5.006666667 211 244 228 219.3333333 227.6666667 0.861917436 0.047276536 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001935///endothelial cell proliferation+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle" 73804 73804 'Kif2c' mRNA 7 8 6 0.14 0.15 0.12 3.49 3.17 2.85 0.136666667 3.17 206 183 163 7 184 7.87E-33 4.705079666 04361///Axon regeneration "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0035371///microtubule plus-end" GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0051010///microtubule plus-end binding+++GO:1990939///ATP-dependent microtubule motor activity GO:0007018///microtubule-based movement+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007080///mitotic metaphase plate congression+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0051301///cell division+++GO:0051310///metaphase plate congression+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051983///regulation of chromosome segregation 73808 73808 'Tex36' mRNA 2 1 0 0.14 0.07 0 0.06 0 0.06 0.07 0.04 1 0 1 1 0.666666667 0.867862767 -0.577623952 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73813 73813 'Fam83e' mRNA 6 4 5 0.11 0.07 0.1 0.08 0.12 0.09 0.093333333 0.096666667 5 7 5 5 5.666666667 0.89764152 0.16974469 GO:0005575///cellular_component GO:0019901///protein kinase binding GO:0007165///signal transduction 73822 73822 'Mfsd12' mRNA 586.17 677.3 592.99 7.98 9.06 8.57 25.43 22.72 23.65 8.536666667 23.93333333 2149 1877.72 1938.88 618.82 1988.533333 1.39E-84 1.673086005 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome GO:0005215///transporter activity+++GO:0015293///symporter activity+++GO:0033229///cysteine transmembrane transporter activity GO:0001942///hair follicle development+++GO:0006865///amino acid transport+++GO:0008643///carbohydrate transport+++GO:0042438///melanin biosynthetic process+++GO:0043473///pigmentation+++GO:0043474///pigment metabolic process involved in pigmentation+++GO:0048021///regulation of melanin biosynthetic process+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0055085///transmembrane transport+++GO:0071702///organic substance transport+++GO:1903712///cysteine transmembrane transport 73825 73825 'Ppp1r21' mRNA 475 510 555 8.78 8.77 10.28 11.51 11.02 11.51 9.276666667 11.34666667 758 709 728 513.3333333 731.6666667 2.78E-05 0.496003296 GO:0005768///endosome+++GO:0005769///early endosome GO:0008150///biological_process 73826 73826 'Poldip3' mRNA 2457 2572 2801 40.78 41.96 49.38 39.32 37.53 41.23 44.04 39.36 2724 2542 2765 2610 2677 0.863090843 0.020904752 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0044877///protein-containing complex binding GO:0006406///mRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0045727///positive regulation of translation+++GO:0051028///mRNA transport 73827 73827 'Tmem198b' mRNA 655.89 640.85 573.68 14.15 13.53 13.44 15.25 15.21 15.43 13.70666667 15.29666667 789.16 758.52 753.43 623.4733333 767.0366667 0.005150656 0.289950472 GO:0005886///plasma membrane+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0090263///positive regulation of canonical Wnt signaling pathway 73828 73828 'Dcaf4' mRNA 434.98 449 492 10.96 11.25 13.32 9.56 9.38 10.63 11.84333333 9.856666667 435 408 463.08 458.66 435.36 0.600422082 -0.089257983 GO:0080008///Cul4-RING E3 ubiquitin ligase complex 73830 73830 'Eif3k' mRNA 1786 1773 1708 139.77 137.51 141.73 147.21 153.07 153.11 139.67 151.13 2155 2179 2160 1755.666667 2164.666667 4.37E-05 0.29076503 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation 73833 73833 'Fam98c' mRNA 548.22 507.43 550.15 26.31 24.03 28.04 16.88 17.69 16.72 26.12666667 17.09666667 403.32 413.13 387.68 535.2666667 401.3766667 8.13E-04 -0.429352572 GO:0072669///tRNA-splicing ligase complex GO:0008150///biological_process 73834 73834 'Atp6v1d' mRNA 2187 2237 2249 92.55 93.4 100.97 100.49 104.43 108.22 95.64 104.38 2728 2763 2840 2224.333333 2777 2.18E-05 0.307592739 00190///Oxidative phosphorylation+++04145///Phagosome+++04150///mTOR signaling pathway+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis GO:0005813///centrosome+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0033176///proton-transporting V-type ATPase complex "GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0030030///cell projection organization+++GO:0055085///transmembrane transport+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1902600///proton transmembrane transport 73835 73835 'Ifitm5' mRNA 8 5 4 0.79 0.49 0.42 2.07 2.04 1.61 0.566666667 1.906666667 24 23 18 5.666666667 21.66666667 0.008030466 1.927713078 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0007275///multicellular organism development+++GO:0030282///bone mineralization+++GO:0030500///regulation of bone mineralization+++GO:0060349///bone morphogenesis 73836 73836 'Slc35b2' mRNA 2670 2843 2733 81.93 86.03 88.05 83.88 85.91 82.04 85.33666667 83.94333333 3194 3186 3025 2748.666667 3135 0.012022841 0.177543188 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005459///UDP-galactose transmembrane transporter activity+++GO:0005460///UDP-glucose transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0046964///3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0015786///UDP-glucose transmembrane transport+++GO:0046963///3'-phosphoadenosine 5'-phosphosulfate transport+++GO:0055085///transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:1902559///3'-phospho-5'-adenylyl sulfate transmembrane transport 73844 73844 'Ankrd45' mRNA 292 314 336 4.32 4.61 5.3 0.84 1.37 1.01 4.743333333 1.073333333 65 103 76 314 81.33333333 5.38E-21 -1.960764913 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73845 73845 'Ankrd42' mRNA 573 605 520 11.23 11.67 10.75 3.81 3.37 3.61 11.21666667 3.596666667 224 197 209 566 210 1.02E-28 -1.440793211 GO:0005634///nucleus GO:0005515///protein binding+++GO:0051059///NF-kappaB binding GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1900017///positive regulation of cytokine production involved in inflammatory response 73847 73847 'Fam110a' mRNA 255 226 239 8.37 7.09 8.15 13.04 14.67 12.51 7.87 13.40666667 459 506 433 240 466 4.20E-11 0.945635023 GO:0000922///spindle pole+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 73852 73852 'D3Ertd751e' mRNA 431 447 403 9.6 9.6 8.46 4.48 3.87 4.48 9.22 4.276666667 247 191 239 427 225.6666667 1.70E-10 -0.932090713 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73862 73862 'Spata48' mRNA 1 2 0 0.04 0.08 0 0 0 0.1 0.04 0.033333333 0 0 2 1 0.666666667 0.881516735 -0.555610648 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73863 73863 '4930415O20Rik' mRNA 3.39 5 4 0.47 0.69 0.59 0.61 0.25 0.38 0.583333333 0.413333333 5 2 3 4.13 3.333333333 0.863090843 -0.280648726 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73873 73873 'Fam161a' mRNA 339 389 327 6.62 7.75 6.51 5.74 6.58 6.82 6.96 6.38 329 328 352 351.6666667 336.3333333 0.691166251 -0.073851221 GO:0000235///astral microtubule+++GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005876///spindle microtubule+++GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0097733///photoreceptor cell cilium GO:0008017///microtubule binding+++GO:0042802///identical protein binding GO:0030030///cell projection organization+++GO:0044782///cilium organization+++GO:0060271///cilium assembly+++GO:1901985///positive regulation of protein acetylation 73884 73884 'Zdbf2' mRNA 81 69 70 0.34 0.29 0.35 0.23 0.17 0.15 0.326666667 0.183333333 60 46 36 73.33333333 47.33333333 0.066588618 -0.645751715 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0043045///DNA methylation involved in embryo development+++GO:0071514///genetic imprinting 73893 73893 'Tmem202' mRNA 13 18.13 14.07 0.83 1.02 0.89 2.91 1.72 2.32 0.913333333 2.316666667 53.07 30 44.2 15.06666667 42.42333333 0.002840262 1.482949876 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 73902 73902 'Psmb11' mRNA 33.73 17.19 24.16 0.43 0.21 0.32 0.18 0.17 0.19 0.32 0.18 15.98 15 17.03 25.02666667 16.00333333 0.295280438 -0.667925747 03050///Proteasome "GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005839///proteasome core complex+++GO:0019774///proteasome core complex, beta-subunit complex" GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity "GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0033077///T cell differentiation in thymus+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043374///CD8-positive, alpha-beta T cell differentiation+++GO:0051603///proteolysis involved in cellular protein catabolic process" 73910 73910 'Arhgap18' mRNA 549 478 527 8.24 7.05 8.38 8.56 8.5 7.82 7.89 8.293333333 657 637 581 518 625 0.043836556 0.257163461 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0030833///regulation of actin filament polymerization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:2000145///regulation of cell motility 73914 73914 'Irak3' mRNA 147 149 136 2.66 2.65 2.63 7.89 7.17 6.87 2.646666667 7.31 502 444 422 144 456 3.04E-28 1.651207597 04722///Neurotrophin signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity GO:0001819///positive regulation of cytokine production+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0009615///response to virus+++GO:0010933///positive regulation of macrophage tolerance induction+++GO:0010936///negative regulation of macrophage cytokine production+++GO:0016310///phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032494///response to peptidoglycan+++GO:0032496///response to lipopolysaccharide+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0042177///negative regulation of protein catabolic process+++GO:0042981///regulation of apoptotic process+++GO:0043242///negative regulation of protein complex disassembly+++GO:0043244///regulation of protein complex disassembly+++GO:0043330///response to exogenous dsRNA+++GO:0043407///negative regulation of MAP kinase activity+++GO:0045824///negative regulation of innate immune response+++GO:0046777///protein autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0070555///response to interleukin-1 73916 73916 'Ift57' mRNA 976 975 185 21.38 21.03 4.3 3.22 8.29 6.27 15.57 5.926666667 169 425 319 712 304.3333333 0.169353715 -1.199649624 05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0044292///dendrite terminus GO:0003677///DNA binding+++GO:0005515///protein binding GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007224///smoothened signaling pathway+++GO:0042073///intraciliary transport+++GO:0042981///regulation of apoptotic process+++GO:0044458///motile cilium assembly+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060972///left/right pattern formation+++GO:1905515///non-motile cilium assembly 73919 73919 'Lyrm1' mRNA 181 179 157 8.79 8.11 7.86 8.19 10.31 8.37 8.253333333 8.956666667 169 194 176 172.3333333 179.6666667 0.85520116 0.051624723 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0030496///midbody GO:0003674///molecular_function GO:0008150///biological_process 73936 73936 'Ccdc175' mRNA 2 1 0 0.04 0.02 0 0 0 0 0.02 0 0 0 0 1 0 0.614783931 -2.421998967 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 73940 73940 'Hapln2' mRNA 3 2 3 0.08 0.05 0.09 0.02 0.02 0 0.073333333 0.013333333 1 1 0 2.666666667 0.666666667 0.383738352 -2.019624043 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0005540///hyaluronic acid binding GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0007417///central nervous system development+++GO:0008065///establishment of blood-nerve barrier+++GO:0085029///extracellular matrix assembly 73942 73942 'Fam151b' mRNA 10 7 8 0.43 0.3 0.37 0.3 0.31 0.16 0.366666667 0.256666667 8 8 4 8.333333333 6.666666667 0.780826139 -0.334993441 GO:0005615///extracellular space GO:0003674///molecular_function GO:0008150///biological_process 73945 73945 'Otud4' mRNA 1398.8 1403.27 1096 10.22 10.04 8.6 8.42 7.75 8.14 9.62 8.103333333 1327 1185 1234 1299.356667 1248.666667 0.575953016 -0.064956617 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0060090///molecular adaptor activity+++GO:0061578///Lys63-specific deubiquitinase activity GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0045087///innate immune response+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1901537///positive regulation of DNA demethylation+++GO:1903093///regulation of protein K48-linked deubiquitination+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway 73988 73988 '4930438A08Rik' mRNA 0 0 3 0 0 0.09 0 0 0.03 0.03 0.01 0 0 1 1 0.333333333 0.734135213 -1.5620629 "00250///Alanine, aspartate and glutamate metabolism+++00270///Cysteine and methionine metabolism+++00280///Valine, leucine and isoleucine degradation+++00350///Tyrosine metabolism+++00360///Phenylalanine metabolism+++00380///Tryptophan metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis" GO:0005575///cellular_component GO:0001716///L-amino-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0046592///polyamine oxidase activity GO:0009063///cellular amino acid catabolic process 73991 73991 'Atl1' mRNA 207 216 193 4.05 4.16 4.01 2.4 2.34 2.29 4.073333333 2.343333333 141 134 130 205.3333333 135 0.001334626 -0.61574745 GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0071782///endoplasmic reticulum tubular network+++GO:0098826///endoplasmic reticulum tubular network membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0007029///endoplasmic reticulum organization+++GO:0007409///axonogenesis+++GO:0051260///protein homooligomerization+++GO:1990809///endoplasmic reticulum tubular network membrane organization 73998 73998 'Herc3' mRNA 288 286 268 3.29 3.46 3.4 2.29 2.18 2.21 3.383333333 2.226666667 217 205 197 280.6666667 206.3333333 0.005499777 -0.455308168 04120///Ubiquitin mediated proteolysis GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity GO:0016567///protein ubiquitination 74002 74002 'Psd2' mRNA 56 43 52 0.64 0.49 0.64 0.35 0.23 0.36 0.59 0.313333333 36 23 35 50.33333333 31.33333333 0.101403017 -0.700613904 04144///Endocytosis+++04361///Axon regeneration GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032154///cleavage furrow+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005543///phospholipid binding GO:0032012///regulation of ARF protein signal transduction 74004 74004 'Jakmip3' mRNA 1 5 0 0.03 0.04 0 0.01 0 0 0.023333333 0.003333333 1 0 0 2 0.333333333 0.43631411 -2.451421821 GO:0005794///Golgi apparatus GO:0003674///molecular_function+++GO:0008017///microtubule binding+++GO:0019900///kinase binding GO:0008150///biological_process 74006 74006 'Dnm1l' mRNA 2346 2356 2258 31.02 30.61 31.64 21.33 21.54 21.09 31.09 21.32 1849 1830 1772 2320 1817 1.13E-07 -0.364214579 04214///Apoptosis - fly+++04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005903///brush border+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0098835///presynaptic endocytic zone membrane+++GO:0099073///mitochondrion-derived vesicle+++GO:0099503///secretory vesicle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0030276///clathrin binding+++GO:0030742///GTP-dependent protein binding+++GO:0031267///small GTPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051433///BH2 domain binding GO:0000266///mitochondrial fission+++GO:0001836///release of cytochrome c from mitochondria+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0006816///calcium ion transport+++GO:0006897///endocytosis+++GO:0007005///mitochondrion organization+++GO:0010468///regulation of gene expression+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0012501///programmed cell death+++GO:0016559///peroxisome fission+++GO:0036466///synaptic vesicle recycling via endosome+++GO:0043065///positive regulation of apoptotic process+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0048312///intracellular distribution of mitochondria+++GO:0048488///synaptic vesicle endocytosis+++GO:0048511///rhythmic process+++GO:0050714///positive regulation of protein secretion+++GO:0051259///protein complex oligomerization+++GO:0060047///heart contraction+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061025///membrane fusion+++GO:0065003///protein-containing complex assembly+++GO:0070266///necroptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:0070585///protein localization to mitochondrion+++GO:0071396///cellular response to lipid+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090149///mitochondrial membrane fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:1900063///regulation of peroxisome organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:1903146///regulation of autophagy of mitochondrion+++GO:1903578///regulation of ATP metabolic process+++GO:1904579///cellular response to thapsigargin+++GO:1904666///regulation of ubiquitin protein ligase activity+++GO:1905395///response to flavonoid+++GO:1990910///response to hypobaric hypoxia+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 74007 74007 'Btbd11' mRNA 149 152 158 1.46 1.35 1.52 0.78 0.71 0.92 1.443333333 0.803333333 97 79 103 153 93 0.001708186 -0.73267443 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046982///protein heterodimerization activity GO:0060395///SMAD protein signal transduction 74008 74008 'Arsg' mRNA 318 334 299 6.59 5.8 5.64 8.61 8.06 8.97 6.01 8.546666667 481 441 473 317 465 2.71E-05 0.541779767 04142///Lysosome GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0033889///N-sulfoglucosamine-3-sulfatase activity+++GO:0046872///metal ion binding GO:0006790///sulfur compound metabolic process 74011 74011 'Slc25a27' mRNA 800 871 828 7.45 7.87 8.11 3.16 3.69 3.21 7.81 3.353333333 379 400 381 833 386.6666667 8.03E-25 -1.118850244 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell GO:0008284///positive regulation of cell proliferation+++GO:0009409///response to cold+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0035356///cellular triglyceride homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0046324///regulation of glucose import+++GO:0048839///inner ear development+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0070997///neuron death 74012 74012 'Rap2b' mRNA 462 363 310 5.93 4.58 4.22 19.09 22.59 22.51 4.91 21.39666667 1713 1980 1956 378.3333333 1883 1.69E-87 2.309500214 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0044291///cell-cell contact zone+++GO:0045121///membrane raft+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding GO:0007165///signal transduction+++GO:0030168///platelet activation+++GO:0030336///negative regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032486///Rap protein signal transduction+++GO:0061097///regulation of protein tyrosine kinase activity+++GO:0070527///platelet aggregation 74013 74013 'Rftn2' mRNA 613.91 684.25 665 9.37 10.6 10.97 10.08 9.1 9.84 10.31333333 9.673333333 721.78 672.55 701.51 654.3866667 698.6133333 0.545267738 0.080839195 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0033227///dsRNA transport+++GO:0043330///response to exogenous dsRNA 74015 74015 'Fcho1' mRNA 1211 1295 1138 20.93 22.04 20.88 3.65 4.21 4.01 21.28333333 3.956666667 244 274 259 1214.666667 259 3.41E-100 -2.238941287 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding GO:0006897///endocytosis+++GO:0048268///clathrin coat assembly+++GO:0072583///clathrin-dependent endocytosis 74016 74016 'Phf19' mRNA 79 86 80 1.22 1.36 1.32 1.43 1.14 1.3 1.3 1.29 106 89 101 81.66666667 98.66666667 0.389792055 0.260236213 GO:0005634///nucleus+++GO:0035098///ESC/E(Z) complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0019827///stem cell population maintenance+++GO:0048863///stem cell differentiation+++GO:0061087///positive regulation of histone H3-K27 methylation" 74018 74018 'Als2' mRNA 558.01 530.56 529.01 5.59 4.77 5.17 5.16 4.55 4.56 5.176666667 4.756666667 561.56 487.11 482.17 539.1933333 510.28 0.523734254 -0.092961155 05014///Amyotrophic lateral sclerosis+++05022///Pathways of neurodegeneration - multiple diseases GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043539///protein serine/threonine kinase activator activity "GO:0001662///behavioral fear response+++GO:0001701///in utero embryonic development+++GO:0001881///receptor recycling+++GO:0006979///response to oxidative stress+++GO:0007032///endosome organization+++GO:0007041///lysosomal transport+++GO:0007409///axonogenesis+++GO:0007528///neuromuscular junction development+++GO:0007626///locomotory behavior+++GO:0008104///protein localization+++GO:0008219///cell death+++GO:0016050///vesicle organization+++GO:0016197///endosomal transport+++GO:0016601///Rac protein signal transduction+++GO:0035249///synaptic transmission, glutamatergic+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0048812///neuron projection morphogenesis+++GO:0051036///regulation of endosome size+++GO:0051260///protein homooligomerization+++GO:0071902///positive regulation of protein serine/threonine kinase activity" 74019 74019 'Traf3ip1' mRNA 394 352 428 6.11 5.38 7.02 5.75 5.64 5.67 6.17 5.686666667 426 408 407 391.3333333 413.6666667 0.742236706 0.063957881 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0030992///intraciliary transport particle B+++GO:0035869///ciliary transition zone+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097542///ciliary tip+++GO:0097546///ciliary base GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0001822///kidney development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0021532///neural tube patterning+++GO:0030030///cell projection organization+++GO:0031076///embryonic camera-type eye development+++GO:0031333///negative regulation of protein complex assembly+++GO:0032480///negative regulation of type I interferon production+++GO:0032688///negative regulation of interferon-beta production+++GO:0035050///embryonic heart tube development+++GO:0036342///post-anal tail morphogenesis+++GO:0042073///intraciliary transport+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042733///embryonic digit morphogenesis+++GO:0050687///negative regulation of defense response to virus+++GO:0051101///regulation of DNA binding+++GO:0060271///cilium assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 74020 74020 'Cpne4' mRNA 14 10 29 0.21 0.15 0.46 0.16 0.15 0.22 0.273333333 0.176666667 12 11 16 17.66666667 13 0.571683846 -0.476222702 GO:0005886///plasma membrane GO:0005515///protein binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0071277///cellular response to calcium ion 74022 74022 'Glyr1' mRNA 2267 2279 2175 36.99 36.27 37.41 39.34 36.85 38.12 36.89 38.10333333 2761 2531 2601 2240.333333 2631 0.001096701 0.21972852 GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol "GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0031491///nucleosome binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding+++GO:0050661///NADP binding+++GO:0051287///NAD binding" GO:0035066///positive regulation of histone acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II 74023 74023 'Rd3' mRNA 58.09 56.95 53.65 0.34 0.33 0.34 0.29 0.21 0.17 0.336666667 0.223333333 55.75 39.55 33.03 56.23 42.77666667 0.324114466 -0.409302338 GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0007601///visual perception+++GO:0015031///protein transport+++GO:0031283///negative regulation of guanylate cyclase activity+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye 74025 74025 'Nphp3' mRNA 309 342 175 3.82 3.85 1.95 1.11 1.47 1.39 3.206666667 1.323333333 131 172 152 275.3333333 151.6666667 1.95E-04 -0.856868069 GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097543///ciliary inversin compartment+++GO:0097546///ciliary base GO:0005515///protein binding "GO:0001822///kidney development+++GO:0001947///heart looping+++GO:0003283///atrial septum development+++GO:0006629///lipid metabolic process+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007368///determination of left/right symmetry+++GO:0016055///Wnt signaling pathway+++GO:0030198///extracellular matrix organization+++GO:0030324///lung development+++GO:0032092///positive regulation of protein binding+++GO:0035469///determination of pancreatic left/right asymmetry+++GO:0045494///photoreceptor cell maintenance+++GO:0048496///maintenance of animal organ identity+++GO:0060027///convergent extension involved in gastrulation+++GO:0060271///cilium assembly+++GO:0060993///kidney morphogenesis+++GO:0071908///determination of intestine left/right asymmetry+++GO:0071909///determination of stomach left/right asymmetry+++GO:0071910///determination of liver left/right asymmetry+++GO:0072189///ureter development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1905515///non-motile cilium assembly+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway" 74026 74026 'Msl1' mRNA 880 830 660 16.97 15.02 13.68 11.86 13.05 14.49 15.22333333 13.13333333 744 772 858 790 791.3333333 0.986408572 -0.003860018 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0072487///MSL complex GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0006325///chromatin organization+++GO:0043984///histone H4-K16 acetylation 74030 74030 'Rin2' mRNA 2379 2348 2313 27.33 26.55 28.2 39.6 39.68 36.17 27.36 38.48333333 3962 3883 3508 2346.666667 3784.333333 4.55E-23 0.677024797 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:1904906///positive regulation of endothelial cell-matrix adhesion via fibronectin+++GO:2001214///positive regulation of vasculogenesis 74032 74032 'Sdr42e1' mRNA 411 407 336 8.57 8.44 7.48 4.27 3.48 4.84 8.163333333 4.196666667 236 188 258 384.6666667 227.3333333 1.43E-06 -0.76815657 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor" GO:0006694///steroid biosynthetic process 74035 74035 'Nol9' mRNA 496.9 437.73 339.95 7.2 6.27 5.24 5.6 7.82 8.14 6.236666667 7.186666667 443.67 600.02 624.55 424.86 556.08 0.022567673 0.387389231 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0045111///intermediate filament cytoskeleton GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0051731///polynucleotide 5'-hydroxyl-kinase activity "GO:0000448///cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000460///maturation of 5.8S rRNA+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0016310///phosphorylation" 74039 74039 'Nfam1' mRNA 81 104 117 1.1 1.39 1.69 13.6 13.98 14.59 1.393333333 14.05666667 1148 1153 1193 100.6666667 1164.666667 1.84E-145 3.518403212 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0004888///transmembrane signaling receptor activity GO:0001819///positive regulation of cytokine production+++GO:0007165///signal transduction+++GO:0030183///B cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0045577///regulation of B cell differentiation+++GO:0050853///B cell receptor signaling pathway+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity 74041 74041 'Ddias' mRNA 10 13 10 0.16 0.21 0.17 1.21 1.2 1.39 0.18 1.266666667 87 84 97 11 89.33333333 6.40E-14 3.012183247 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007286///spermatid development+++GO:0030097///hemopoiesis+++GO:0034644///cellular response to UV+++GO:0051726///regulation of cell cycle+++GO:0071345///cellular response to cytokine stimulus+++GO:0071447///cellular response to hydroperoxide+++GO:0071480///cellular response to gamma radiation+++GO:0071850///mitotic cell cycle arrest+++GO:0097752///regulation of DNA stability+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:2000270///negative regulation of fibroblast apoptotic process 74043 74043 'Pex26' mRNA 279 275 186 3.73 3.65 2.71 2.56 2.48 2.09 3.363333333 2.376666667 221 195 171 246.6666667 195.6666667 0.101428662 -0.339730155 04146///Peroxisome GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008022///protein C-terminus binding+++GO:0044877///protein-containing complex binding+++GO:0051117///ATPase binding GO:0015031///protein transport+++GO:0016558///protein import into peroxisome matrix+++GO:0045046///protein import into peroxisome membrane 74044 74044 'Ttf2' mRNA 133 142 133 1.58 1.65 1.67 2.53 2.08 2.22 1.633333333 2.276666667 247 197 210 136 218 5.67E-04 0.667463634 04918///Thyroid hormone synthesis GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070615///nucleosome-dependent ATPase activity "GO:0006353///DNA-templated transcription, termination+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing" 74048 74048 'Vsir' mRNA 470 485 475 5.19 5.27 5.56 20.72 20.52 20.8 5.34 20.68 2161 2090 2101 476.6666667 2117.333333 5.41E-150 2.139169393 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0061133///endopeptidase activator activity "GO:0002725///negative regulation of T cell cytokine production+++GO:0010628///positive regulation of gene expression+++GO:0010950///positive regulation of endopeptidase activity+++GO:0030335///positive regulation of cell migration+++GO:0030509///BMP signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0031638///zymogen activation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0048863///stem cell differentiation+++GO:0050776///regulation of immune response+++GO:0120158///positive regulation of collagen catabolic process+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:2000565///negative regulation of CD8-positive, alpha-beta T cell proliferation+++GO:2000738///positive regulation of stem cell differentiation" 74051 74051 'Steap2' mRNA 402 436 336 2.79 3 2.49 3.2 2.36 2.71 2.76 2.756666667 512 373 433 391.3333333 439.3333333 0.353123637 0.156816635 04978///Mineral absorption GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030173///integral component of Golgi membrane GO:0008823///cupric reductase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0052851///ferric-chelate reductase (NADPH) activity GO:0006811///ion transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0006897///endocytosis+++GO:0009725///response to hormone+++GO:0015677///copper ion import+++GO:0045055///regulated exocytosis+++GO:0055072///iron ion homeostasis+++GO:0098705///copper ion import across plasma membrane+++GO:0098706///ferric iron import across cell outer membrane+++GO:0098711///iron ion import across plasma membrane 74052 74052 'Ttc21a' mRNA 3030 3054 2759 35.37 35.73 35.32 3.32 2.82 3.75 35.47333333 3.296666667 351 306 362 2947.666667 339.6666667 0 -3.128246252 GO:0005929///cilium+++GO:0030991///intraciliary transport particle A GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0035721///intraciliary retrograde transport+++GO:0061512///protein localization to cilium 74053 74053 'Grip1' mRNA 839.2 814.72 801.92 2.14 2.27 2.82 0.86 0.74 0.73 2.41 0.776666667 400.85 358.95 351.18 818.6133333 370.3266667 1.12E-26 -1.158639713 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055037///recycling endosome+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0035259///glucocorticoid receptor binding "GO:0007399///nervous system development+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0016358///dendrite development+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0140059///dendrite arborization+++GO:0150012///positive regulation of neuron projection arborization" 74054 74054 '4931406B18Rik' mRNA 1 0 0 0.01 0 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0033691///sialic acid binding GO:0007155///cell adhesion 74055 74055 'Plce1' mRNA 1460 1667 1450 8.25 9.34 8.69 5.34 4.68 4.87 8.76 4.963333333 1041 904 945 1525.666667 963.3333333 4.46E-15 -0.674840051 00562///Inositol phosphate metabolism+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04024///cAMP signaling pathway+++04070///Phosphatidylinositol signaling system+++04919///Thyroid hormone signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05131///Shigellosis+++05205///Proteoglycans in cancer GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0000187///activation of MAPK activity+++GO:0006629///lipid metabolic process+++GO:0006651///diacylglycerol biosynthetic process+++GO:0007165///signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0016042///lipid catabolic process+++GO:0032835///glomerulus development+++GO:0035556///intracellular signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0045859///regulation of protein kinase activity+++GO:0046578///regulation of Ras protein signal transduction+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0050790///regulation of catalytic activity 74071 74071 'Lmntd1' mRNA 24 22 20 0.53 0.48 0.47 0.31 0.15 0.22 0.493333333 0.226666667 14 8 11 22 11 0.124137126 -1.013301788 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament GO:0003674///molecular_function GO:0008283///cell proliferation 74075 74075 'Syce1' mRNA 3 7 2 0.12 0.28 0.09 0.14 0.07 0.18 0.163333333 0.13 4 2 5 4 3.666666667 0.94226925 -0.122864148 GO:0000795///synaptonemal complex+++GO:0000801///central element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization 74080 74080 'Nmnat3' mRNA 309 285 349 8.86 7.99 10.34 3.8 3.86 3.59 9.063333333 3.75 143 150 128 314.3333333 140.3333333 7.88E-11 -1.179792512 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0000166///nucleotide binding+++GO:0000309///nicotinamide-nucleotide adenylyltransferase activity+++GO:0003824///catalytic activity+++GO:0004515///nicotinate-nucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity GO:0009058///biosynthetic process+++GO:0009435///NAD biosynthetic process+++GO:0009611///response to wounding+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0034612///response to tumor necrosis factor 74081 74081 'Cep350' mRNA 704 742 675 2.76 2.86 2.8 2.52 2.31 2.64 2.806666667 2.49 740 664 751 707 718.3333333 0.933539926 0.011547987 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0034453///microtubule anchoring+++GO:0071539///protein localization to centrosome+++GO:1905515///non-motile cilium assembly 74087 74087 'Slc7a13' mRNA 0 1 2 0 0.03 0.06 0.07 0.02 0.05 0.03 0.046666667 3 1 2 1 2 0.724936039 0.956142232 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005515///protein binding+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0046982///protein heterodimerization activity GO:0003333///amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0015810///aspartate transmembrane transport+++GO:0015811///L-cystine transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0055085///transmembrane transport 74088 74088 'Them7' mRNA 91 86 91 3.39 3.19 3.56 0.34 0.42 0.49 3.38 0.416666667 10 12 14 89.33333333 12 1.48E-13 -2.908578724 GO:0005739///mitochondrion GO:0047617///acyl-CoA hydrolase activity GO:0008150///biological_process 74090 74090 'Paqr5' mRNA 634 630 651 9.94 9.74 10.85 8.51 8.22 9.14 10.17666667 8.623333333 621 588 650 638.3333333 619.6666667 0.705730223 -0.056082527 05207///Chemical carcinogenesis - receptor activation GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0048477///oogenesis 74091 74091 'Npl' mRNA 142 125 131 6.04 5.25 5.92 46.96 50.45 46.63 5.736666667 48.01333333 1267 1328 1217 132.6666667 1270.666667 8.01E-161 3.248573404 00520///Amino sugar and nucleotide sugar metabolism GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0008747///N-acetylneuraminate lyase activity+++GO:0016829///lyase activity+++GO:0042802///identical protein binding GO:0005975///carbohydrate metabolic process+++GO:0019262///N-acetylneuraminate catabolic process 74094 74094 'Tjap1' mRNA 9956 10314 8945 204.39 206.42 194.36 28.1 27.68 27.75 201.7233333 27.84333333 1533 1496 1492 9738.333333 1507 0 -2.701604368 04530///Tight junction GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0005515///protein binding GO:0007030///Golgi organization 74096 74096 'Hvcn1' mRNA 66.29 48.89 69.63 1.35 0.97 1.49 8.7 7.62 8.86 1.27 8.393333333 479.86 416.92 477.36 61.60333333 458.0466667 7.68E-54 2.890644954 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0022843///voltage-gated cation channel activity+++GO:0030171///voltage-gated proton channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0009268///response to pH+++GO:0010043///response to zinc ion+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034765///regulation of ion transmembrane transport+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071294///cellular response to zinc ion+++GO:0071467///cellular response to pH+++GO:1902600///proton transmembrane transport 74097 74097 'Pop7' mRNA 314 310 269 27.1 26.52 24.63 32.35 31.9 36.79 26.08333333 33.68 429 412 471 297.6666667 437.3333333 7.24E-05 0.545649694 03008///Ribosome biogenesis in eukaryotes GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030681///multimeric ribonuclease P complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0004526///ribonuclease P activity+++GO:0016787///hydrolase activity+++GO:0033204///ribonuclease P RNA binding "GO:0001682///tRNA 5'-leader removal+++GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 74098 74098 'Czib' mRNA 757 659 786 30.72 26.15 34.07 30.32 29.07 26.39 30.31333333 28.59333333 838 786 705 734 776.3333333 0.683502828 0.064718271 GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 74100 74100 'Arpp21' mRNA 38 33 25 0.54 0.55 0.42 0.17 0.26 0.19 0.503333333 0.206666667 12 17 15 32 14.66666667 0.038386222 -1.128929872 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0005516///calmodulin binding GO:0034605///cellular response to heat 74102 74102 'Slc35a5' mRNA 792 761 769 10.19 9.64 10.52 7.57 8.08 7.85 10.11666667 7.833333333 677 705 681 774 687.6666667 0.099939051 -0.182557651 GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity GO:0008643///carbohydrate transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport 74103 74103 'Nebl' mRNA 9724 10012 8654 59.61 61.31 57.66 28.19 26.36 28.94 59.52666667 27.83 5376 4869 5263 9463.333333 5169.333333 1.39E-60 -0.882398812 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0030018///Z disc GO:0003779///actin binding+++GO:0005523///tropomyosin binding+++GO:0008092///cytoskeletal protein binding+++GO:0031005///filamin binding+++GO:0046872///metal ion binding+++GO:0051015///actin filament binding GO:0048747///muscle fiber development+++GO:0071691///cardiac muscle thin filament assembly 74104 74104 'Abcb6' mRNA 407 396 454 7.36 7.06 8.71 4.43 5.09 3.79 7.71 4.436666667 282 317 234 419 277.6666667 1.91E-04 -0.60847728 02010///ABC transporters GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032585///multivesicular body membrane+++GO:0033162///melanosome membrane+++GO:0036020///endolysosome membrane+++GO:0070062///extracellular exosome "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015439///heme-transporting ATPase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0020037///heme binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0046906///tetrapyrrole binding" GO:0006778///porphyrin-containing compound metabolic process+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0006810///transport+++GO:0006878///cellular copper ion homeostasis+++GO:0007420///brain development+++GO:0015886///heme transport+++GO:0033013///tetrapyrrole metabolic process+++GO:0035351///heme transmembrane transport+++GO:0042168///heme metabolic process+++GO:0043588///skin development+++GO:0055085///transmembrane transport+++GO:0098849///cellular detoxification of cadmium ion+++GO:1903232///melanosome assembly 74105 74105 'Gga2' mRNA 691.02 680.53 241.8 7.56 7.32 2.8 3.87 5.49 5.52 5.893333333 4.96 407.99 564.34 562.59 537.7833333 511.64 0.927009975 -0.05925658 04142///Lysosome GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031901///early endosome membrane GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0035091///phosphatidylinositol binding+++GO:0043130///ubiquitin binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0034394///protein localization to cell surface+++GO:0043001///Golgi to plasma membrane protein transport 74106 74106 'Dcaf6' mRNA 627 581 326 10.32 9.5 5.72 6.35 5.39 5.23 8.513333333 5.656666667 438 365 352 511.3333333 385 0.034475698 -0.410681033 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0030374///nuclear receptor transcription coactivator activity GO:0016567///protein ubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II 74107 74107 'Cep55' mRNA 3 9 8 0.07 0.2 0.18 2.71 2.4 2.46 0.15 2.523333333 148 126 129 6.666666667 134.3333333 3.77E-24 4.319037072 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030496///midbody+++GO:0032154///cleavage furrow+++GO:0034451///centriolar satellite+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0000281///mitotic cytokinesis+++GO:0007049///cell cycle+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0045184///establishment of protein localization+++GO:0051301///cell division+++GO:0061952///midbody abscission+++GO:1904888///cranial skeletal system development 74108 74108 'Parn' mRNA 1165 1266 1153 22.07 23.66 23.18 14.81 14.01 14.98 22.97 14.6 896 829 879 1194.666667 868 5.80E-08 -0.472368696 03018///RNA degradation GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0000175///3'-5'-exoribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0043169///cation binding+++GO:0046872///metal ion binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0000495///box H/ACA snoRNA 3'-end processing+++GO:0006402///mRNA catabolic process+++GO:0010587///miRNA catabolic process+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0090669///telomerase RNA stabilization+++GO:0110008///ncRNA deadenylation+++GO:1904872///regulation of telomerase RNA localization to Cajal body" 74111 74111 'Rbm19' mRNA 308 276 267 4.21 3.71 3.87 4.49 4.15 3.98 3.93 4.206666667 378 341 325 283.6666667 348 0.070353821 0.283133883 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0007275///multicellular organism development+++GO:0040019///positive regulation of embryonic development" 74112 74112 'Usp16' mRNA 710.89 720.51 741.95 13.61 13.51 15.1 13.91 13.28 14.17 14.07333333 13.78666667 837.76 782.36 827.52 724.45 815.88 0.15668749 0.158521742 GO:0005634///nucleus GO:0003713///transcription coactivator activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042393///histone binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding "GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045901///positive regulation of translational elongation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051289///protein homotetramerization+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0140014///mitotic nuclear division" 74114 74114 'Crot' mRNA 1422 1463 1413 26.47 27.36 28.08 27.75 26.71 24.35 27.30333333 26.27 1673 1563 1448 1432.666667 1561.333333 0.230178025 0.111404493 04146///Peroxisome GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0043231///intracellular membrane-bounded organelle "GO:0008458///carnitine O-octanoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006091///generation of precursor metabolites and energy+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009410///response to xenobiotic stimulus+++GO:0009437///carnitine metabolic process+++GO:0015908///fatty acid transport+++GO:0015936///coenzyme A metabolic process+++GO:0042493///response to drug+++GO:0051791///medium-chain fatty acid metabolic process 74116 74116 'Pi16' mRNA 9 6 2 0.23 0.19 0.08 0.46 0.63 0.67 0.166666667 0.586666667 21 27 24 5.666666667 24 0.004040535 2.086211204 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development 74117 74117 'Actr3' mRNA 2607 2847 2524 56.15 60.25 57.68 139.74 134.94 141.47 58.02666667 138.7166667 7432 7028 7299 2659.333333 7253 2.90E-147 1.436684384 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0000139///Golgi membrane+++GO:0001726///ruffle+++GO:0002102///podosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005885///Arp2/3 protein complex+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0030027///lamellipodium+++GO:0030056///hemidesmosome+++GO:0031252///cell leading edge+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0060076///excitatory synapse+++GO:0061825///podosome core+++GO:0061828///apical tubulobulbar complex+++GO:0061830///concave side of sperm head+++GO:0061831///apical ectoplasmic specialization+++GO:0061832///basal ectoplasmic specialization+++GO:0061851///leading edge of lamellipodium+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding+++GO:0051117///ATPase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0008356///asymmetric cell division+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010763///positive regulation of fibroblast migration+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0030030///cell projection organization+++GO:0030517///negative regulation of axon extension+++GO:0030838///positive regulation of actin filament polymerization+++GO:0032092///positive regulation of protein binding+++GO:0033206///meiotic cytokinesis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0043519///regulation of myosin II filament organization+++GO:0045666///positive regulation of neuron differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048708///astrocyte differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051321///meiotic cell cycle+++GO:0051491///positive regulation of filopodium assembly+++GO:0051653///spindle localization+++GO:0051965///positive regulation of synapse assembly+++GO:0060271///cilium assembly+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0071346///cellular response to interferon-gamma+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904171///negative regulation of bleb assembly+++GO:2000251///positive regulation of actin cytoskeleton reorganization 74120 74120 'Zfp263' mRNA 1341 1537 1319 22.46 25.14 23.35 21.08 19.55 20.76 23.65 20.46333333 1449 1314 1390 1399 1384.333333 0.826884487 -0.026023401 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 74121 74121 'Acoxl' mRNA 3.01 3.02 1 0.04 0.04 0.01 0.05 0.07 0.02 0.03 0.046666667 4.01 5.01 1 2.343333333 3.34 0.795872331 0.519041018 GO:0005777///peroxisome "GO:0003997///acyl-CoA oxidase activity+++GO:0005504///fatty acid binding+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0055088///lipid homeostasis 74122 74122 'Tmem43' mRNA 1086 1221 1290 20.63 22.83 25.99 33.6 35.35 35.94 23.15 34.96333333 2035 2091 2108 1199 2078 2.62E-17 0.77894499 GO:0005634///nucleus+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding+++GO:0043621///protein self-association GO:0071763///nuclear membrane organization 74123 74123 'Foxp4' mRNA 588 538 300 8.26 7.5 4.52 5.46 4.55 5.59 6.76 5.2 441 355 435 475.3333333 410.3333333 0.324279646 -0.212982217 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0048617///embryonic foregut morphogenesis+++GO:0061140///lung secretory cell differentiation+++GO:1901249///regulation of lung goblet cell differentiation+++GO:1901250///negative regulation of lung goblet cell differentiation" 74125 74125 'Armc8' mRNA 981 899 936 12.35 10.94 12.48 9.19 9.66 8.95 11.92333333 9.266666667 851 867 795 938.6666667 837.6666667 0.099472092 -0.176772052 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0034657///GID complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 74126 74126 'Syvn1' mRNA 1746 1600 1257 28.8 26.11 21.91 20.77 23.4 19.12 25.60666667 21.09666667 1464 1584 1292 1534.333333 1446.666667 0.489612231 -0.090545203 04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum GO:0000151///ubiquitin ligase complex+++GO:0000836///Hrd1p ubiquitin ligase complex+++GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0044322///endoplasmic reticulum quality control compartment GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990381///ubiquitin-specific protease binding "GO:0001701///in utero embryonic development+++GO:0002327///immature B cell differentiation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006986///response to unfolded protein+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0030163///protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0036503///ERAD pathway+++GO:0050821///protein stabilization+++GO:0070936///protein K48-linked ubiquitination+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway" 74127 74127 'Krt80' mRNA 89 68 40 1.6 1.2 0.78 5.29 4.73 5.21 1.193333333 5.076666667 336 296 322 65.66666667 318 1.15E-24 2.271981149 GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0045095///keratin filament+++GO:0045111///intermediate filament cytoskeleton 74129 74129 'Dmgdh' mRNA 182 208 180 3.36 3.78 3.52 1.94 2.45 2.47 3.553333333 2.286666667 121 149 149 190 139.6666667 0.033054443 -0.45253568 "00260///Glycine, serine and threonine metabolism" GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0005542///folic acid binding+++GO:0016491///oxidoreductase activity+++GO:0047865///dimethylglycine dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding GO:0006579///amino-acid betaine catabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0042426///choline catabolic process 74131 74131 'Sash3' mRNA 59 63 40 1.22 1.28 0.88 12.3 12.76 14.67 1.126666667 13.24333333 684 693 790 54 722.3333333 3.60E-104 3.73481613 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0002639///positive regulation of immunoglobulin production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0002821///positive regulation of adaptive immune response+++GO:0030890///positive regulation of B cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042102///positive regulation of T cell proliferation+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0046622///positive regulation of organ growth+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0051251///positive regulation of lymphocyte activation" 74132 74132 'Rnf6' mRNA 2745 2966 2942 46 48.88 52.25 36.84 37 34.73 49.04333333 36.19 2532 2462 2307 2884.333333 2433.666667 7.37E-04 -0.258549877 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0030424///axon+++GO:0031965///nuclear membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0061630///ubiquitin protein ligase activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0030517///negative regulation of axon extension+++GO:0044314///protein K27-linked ubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0070936///protein K48-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination" 74133 74133 'Smg8' mRNA 343 362 346 5.82 6.05 6.23 5.96 5.99 5.77 6.033333333 5.906666667 404 397 379 350.3333333 393.3333333 0.309653588 0.155098574 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0045859///regulation of protein kinase activity" 74134 74134 'Cyp2s1' mRNA 819 845 760 17.33 17.6 17.06 6.66 5.41 5.58 17.33 5.883333333 362 287 294 808 314.3333333 2.85E-32 -1.374235411 00830///Retinol metabolism+++00980///Metabolism of xenobiotics by cytochrome P450 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0004796///thromboxane-A synthase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0036134///12-hydroxyheptadecatrienoic acid synthase activity+++GO:0046872///metal ion binding" GO:0006082///organic acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042573///retinoic acid metabolic process+++GO:0042738///exogenous drug catabolic process 74136 74136 'Sec14l1' mRNA 3108 3331 3068 37.9 40.6 40.9 33.7 30.45 31.57 39.8 31.90666667 3339 2929 3046 3169 3104.666667 0.624154209 -0.041945938 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0039552///RIG-I binding GO:0002376///immune system process+++GO:0009968///negative regulation of signal transduction+++GO:0015871///choline transport+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0045087///innate immune response 74137 74137 'Nuak2' mRNA 164 157 181 3.06 2.86 3.46 7.43 7.18 6.66 3.126666667 7.09 450 432 413 167.3333333 431.6666667 5.96E-19 1.352424538 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:0043066///negative regulation of apoptotic process 74140 74140 'Tm9sf1' mRNA 2347.36 2206 2336.4 53.65 49.81 56.25 63.65 57.52 58.88 53.23666667 60.01666667 3146.44 2787.02 2843.55 2296.586667 2925.67 1.04E-05 0.334752625 GO:0000421///autophagosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006914///autophagy+++GO:0072657///protein localization to membrane 74142 74142 'Lonp1' mRNA 1720 1787 564 31.87 32.58 11.08 9.58 17.33 15.02 25.17666667 13.97666667 595 1051 903 1357 849.6666667 0.299614118 -0.658195323 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0042645///mitochondrial nucleoid GO:0000166///nucleotide binding+++GO:0001018///mitochondrial promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004176///ATP-dependent peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005524///ATP binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0043565///sequence-specific DNA binding+++GO:0051880///G-quadruplex DNA binding+++GO:0070182///DNA polymerase binding GO:0001666///response to hypoxia+++GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007005///mitochondrion organization+++GO:0007568///aging+++GO:0009725///response to hormone+++GO:0010044///response to aluminum ion+++GO:0030163///protein catabolic process+++GO:0034599///cellular response to oxidative stress+++GO:0034622///cellular protein-containing complex assembly+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0070407///oxidation-dependent protein catabolic process 74143 74143 'Opa1' mRNA 1049.51 1098.47 1011.06 8.82 9.02 8.83 8.28 7.79 7.32 8.89 7.796666667 1168.34 1020.55 964.14 1053.013333 1051.01 0.901436583 -0.015086541 05017///Spinocerebellar ataxia GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0030425///dendrite+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0019900///kinase binding+++GO:0044877///protein-containing complex binding+++GO:0070300///phosphatidic acid binding+++GO:1901612///cardiolipin binding GO:0000002///mitochondrial genome maintenance+++GO:0000266///mitochondrial fission+++GO:0001843///neural tube closure+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0006915///apoptotic process+++GO:0007005///mitochondrion organization+++GO:0007007///inner mitochondrial membrane organization+++GO:0007568///aging+++GO:0007601///visual perception+++GO:0008053///mitochondrial fusion+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0014042///positive regulation of neuron maturation+++GO:0014850///response to muscle activity+++GO:0031667///response to nutrient levels+++GO:0036444///calcium import into the mitochondrion+++GO:0043066///negative regulation of apoptotic process+++GO:0046039///GTP metabolic process+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0048312///intracellular distribution of mitochondria+++GO:0050896///response to stimulus+++GO:0051259///protein complex oligomerization+++GO:0051602///response to electrical stimulus+++GO:0060041///retina development in camera-type eye+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0061025///membrane fusion+++GO:0070584///mitochondrion morphogenesis+++GO:0071333///cellular response to glucose stimulus+++GO:0071456///cellular response to hypoxia+++GO:0090102///cochlea development+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090398///cellular senescence+++GO:0097749///membrane tubulation+++GO:1900006///positive regulation of dendrite development+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1904643///response to curcumin+++GO:1905232///cellular response to L-glutamate+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway 74144 74144 'Robo4' mRNA 368 410 347 5.33 5.96 5.31 6.36 6.27 6.87 5.533333333 6.5 498 461 514 375 491 0.003411368 0.378757369 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0030336///negative regulation of cell migration+++GO:0061028///establishment of endothelial barrier+++GO:0098609///cell-cell adhesion 74145 74145 'F13a1' mRNA 538 551 492 7.46 7.52 7.26 85.63 82.09 84.87 7.413333333 84.19666667 7094 6639 6806 527 6846.333333 0 3.688659825 04610///Complement and coagulation cascades+++05171///Coronavirus disease - COVID-19 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0062023///collagen-containing extracellular matrix "GO:0000166///nucleotide binding+++GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" "GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0018149///peptide cross-linking+++GO:0072378///blood coagulation, fibrin clot formation" 74147 74147 'Ehhadh' mRNA 228 274 287 4.21 4.99 5.61 2.73 3.36 3.05 4.936666667 3.046666667 170 206 183 263 186.3333333 0.008032767 -0.51064138 "00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++00650///Butanoate metabolism+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome" GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005829///cytosol "GO:0003824///catalytic activity+++GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016491///oxidoreductase activity+++GO:0016509///long-chain-3-hydroxyacyl-CoA dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0019899///enzyme binding+++GO:0070403///NAD+ binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0006637///acyl-CoA metabolic process+++GO:0008152///metabolic process 74148 74148 'Cluh' mRNA 1091 1211 902 10.74 11.7 9.51 9.15 9.75 11.01 10.65 9.97 1061 1109 1246 1068 1138.666667 0.504128854 0.086585132 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006996///organelle organization+++GO:0007005///mitochondrion organization+++GO:0048312///intracellular distribution of mitochondria 74149 74149 'Zfp946' mRNA 180 216 200 3.31 3.91 3.91 2.97 3.38 2.97 3.71 3.106666667 185 206 178 198.6666667 189.6666667 0.754095254 -0.078160046 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 74150 74150 'Slc35f5' mRNA 1303 1443 1478 26.16 28.51 31.5 26.45 27.87 25.73 28.72333333 26.68333333 1514 1556 1427 1408 1499 0.501147059 0.076537412 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 74152 74152 'Stra6l' mRNA 3 2 1 0.05 0.03 0.01 1.12 1.03 1.01 0.03 1.053333333 87 78 80 2 81.66666667 1.62E-14 5.342263961 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0034633///retinol transport+++GO:0071939///vitamin A import 74153 74153 'Uba7' mRNA 596 599 626 10.32 10.2 11.49 17.75 16.46 16.12 10.67 16.77666667 1180 1069 1038 607 1095.666667 2.22E-17 0.837814042 04120///Ubiquitin mediated proteolysis+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004839///ubiquitin activating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0016874///ligase activity+++GO:0019782///ISG15 activating enzyme activity GO:0006464///cellular protein modification process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0032020///ISG15-protein conjugation+++GO:0032446///protein modification by small protein conjugation 74154 74154 'Unkl' mRNA 994.6 1045.4 1011.24 12.25 12.97 14.12 5.86 5.08 5.97 13.11333333 5.636666667 543.22 459.33 527.66 1017.08 510.07 2.09E-23 -1.009482924 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination 74155 74155 'Errfi1' mRNA 3354 3458 3236 60.37 61.26 61.79 61.8 65.42 59.78 61.14 62.33333333 3950 4084 3700 3349.333333 3911.333333 0.001534597 0.21277734 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019900///kinase binding+++GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032869///cellular response to insulin stimulus+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043589///skin morphogenesis+++GO:0045616///regulation of keratinocyte differentiation+++GO:0048286///lung alveolus development+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0060426///lung vasculature development+++GO:0060428///lung epithelium development+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071474///cellular hyperosmotic response+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress 74156 74156 'Acot12' mRNA 9 8 5 0.24 0.19 0.1 0.1 0.03 0 0.176666667 0.043333333 4 1 0 7.333333333 1.666666667 0.130393078 -2.151647178 00620///Pyruvate metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003986///acetyl-CoA hydrolase activity+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0016787///hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0042802///identical protein binding+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006084///acetyl-CoA metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process 74157 74157 'Cmtr1' mRNA 3216.37 3318.63 3381.88 26.7 27.08 29.77 22.24 22.46 20.87 27.85 21.85666667 3085.52 3044.81 2804.25 3305.626667 2978.193333 0.034367229 -0.164079851 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0004483///mRNA (nucleoside-2'-O-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity GO:0006370///7-methylguanosine mRNA capping+++GO:0006397///mRNA processing+++GO:0032259///methylation+++GO:0080009///mRNA methylation+++GO:0097309///cap1 mRNA methylation 74158 74158 'Josd1' mRNA 315 288 215 5.06 4.55 3.66 3.36 3.54 3.76 4.423333333 3.553333333 241 248 261 272.6666667 250 0.535800008 -0.13052065 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination 74159 74159 'Acbd5' mRNA 1248 1226 1259 18.33 17.89 19.58 16.99 14.83 15.48 18.6 15.76666667 1321 1136 1177 1244.333333 1211.333333 0.649174326 -0.053038029 GO:0005654///nucleoplasm+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000062///fatty-acyl-CoA binding+++GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0006914///autophagy+++GO:0030242///autophagy of peroxisome 74164 74164 'Nfx1' mRNA 2309 2270 2263 29.09 27.7 30.01 20.31 19.68 19.79 28.93333333 19.92666667 1856 1736 1749 2280.666667 1780.333333 1.91E-07 -0.370166221 05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005886///plasma membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0051865///protein autoubiquitination" 74165 74165 'Fbxl22' mRNA 49.85 22.01 35.64 0.68 0.3 0.52 0.68 0.42 0.57 0.5 0.556666667 57.72 34.67 47.51 35.83333333 46.63333333 0.485291592 0.362478692 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex+++GO:0030018///Z disc GO:0061630///ubiquitin protein ligase activity GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051726///regulation of cell cycle 74166 74166 'Tmem38a' mRNA 853 870 807 20.89 20.62 20.77 15.06 15.58 14.75 20.76 15.13 722 736 684 843.3333333 714 0.013260273 -0.251000375 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031965///nuclear membrane+++GO:0033017///sarcoplasmic reticulum membrane GO:0005261///cation channel activity+++GO:0005267///potassium channel activity+++GO:0015269///calcium-activated potassium channel activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0007029///endoplasmic reticulum organization+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0071313///cellular response to caffeine+++GO:0071805///potassium ion transmembrane transport+++GO:0098662///inorganic cation transmembrane transport 74167 74167 'Nudt9' mRNA 2065 2036 1411 77.37 75.75 54.34 62.98 81.89 75.16 69.15333333 73.34333333 1886 2402 2193 1837.333333 2160.333333 0.067193685 0.232349865 00230///Purine metabolism GO:0005739///mitochondrion+++GO:0016604///nuclear body+++GO:0030054///cell junction+++GO:0031965///nuclear membrane GO:0016787///hydrolase activity+++GO:0047631///ADP-ribose diphosphatase activity GO:0046032///ADP catabolic process+++GO:0046709///IDP catabolic process 74168 74168 'Zdhhc16' mRNA 1773.05 1858.98 1757.09 51.97 54.04 55.75 34.48 33.61 31.65 53.92 33.24666667 1318.82 1268.4 1194.22 1796.373333 1260.48 1.00E-11 -0.523382575 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005515///protein binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity" GO:0001654///eye development+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007507///heart development+++GO:0018345///protein palmitoylation+++GO:0021537///telencephalon development 74176 74176 'Tgm5' mRNA 90 83 52 1.91 1.74 1.17 0.2 0.11 0.15 1.606666667 0.153333333 11 6 8 75 8.333333333 1.16E-11 -3.174586552 GO:0005575///cellular_component+++GO:0005737///cytoplasm "GO:0003810///protein-glutamine gamma-glutamyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding" GO:0018149///peptide cross-linking 74178 74178 'Stk40' mRNA 374 350 320 5.78 5.29 5.23 7.01 5.89 7.19 5.433333333 6.696666667 521 431 520 348 490.6666667 3.20E-04 0.484409098 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0003016///respiratory system process+++GO:0005977///glycogen metabolic process+++GO:0006468///protein phosphorylation+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0030324///lung development+++GO:0035264///multicellular organism growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0048286///lung alveolus development+++GO:0060425///lung morphogenesis 74180 74180 'Muc5b' mRNA 137 111 99 0.48 0.38 0.36 0.03 0.05 0 0.406666667 0.026666667 11 15 1 115.6666667 9 7.37E-17 -3.691605659 04657///IL-17 signaling pathway+++04970///Salivary secretion GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0042742///defense response to bacterium+++GO:0043030///regulation of macrophage activation 74182 74182 'Gpcpd1' mRNA 1374 1468 1321 20.38 21.44 20.76 17.76 18.17 17.95 20.86 17.96 1377 1371 1346 1387.666667 1364.666667 0.747865658 -0.034727451 00564///Glycerophospholipid metabolism+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008081///phosphoric diester hydrolase activity+++GO:0008889///glycerophosphodiester phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0030246///carbohydrate binding+++GO:0047389///glycerophosphocholine phosphodiesterase activity+++GO:2001070///starch binding GO:0006629///lipid metabolic process+++GO:0007519///skeletal muscle tissue development+++GO:0046475///glycerophospholipid catabolic process 74183 74183 'Perm1' mRNA 141 189 114 1.78 2.3 1.5 0.75 0.95 0.96 1.86 0.886666667 69 86 86 148 80.33333333 7.26E-04 -0.883372681 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0014850///response to muscle activity" 74185 74185 'Gbe1' mRNA 872 916 853 16.03 16.58 16.64 9.06 8.89 8.5 16.41666667 8.816666667 567 543 515 880.3333333 541.6666667 6.93E-13 -0.712312075 00500///Starch and sucrose metabolism GO:0005737///cytoplasm "GO:0003824///catalytic activity+++GO:0003844///1,4-alpha-glucan branching enzyme activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0043169///cation binding+++GO:0102752///1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)" GO:0005975///carbohydrate metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0043524///negative regulation of neuron apoptotic process 74186 74186 'Ccdc3' mRNA 289 301 53 6.01 6.17 1.17 1.86 2.95 2.65 4.45 2.486666667 103 159 142 214.3333333 134.6666667 0.464280853 -0.647797856 GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum GO:0003674///molecular_function GO:0010629///negative regulation of gene expression+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045833///negative regulation of lipid metabolic process+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0051055///negative regulation of lipid biosynthetic process 74187 74187 'Katnb1' mRNA 868 843 919 17.62 16.84 19.61 11.99 11.35 9.72 18.02333333 11.02 663 616 523 876.6666667 600.6666667 1.78E-06 -0.560793332 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0008352///katanin complex+++GO:0015630///microtubule cytoskeleton+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0043025///neuronal cell body GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0046982///protein heterodimerization activity+++GO:0060590///ATPase regulator activity+++GO:0070840///dynein complex binding GO:0007019///microtubule depolymerization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0010942///positive regulation of cell death+++GO:0010976///positive regulation of neuron projection development+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0050790///regulation of catalytic activity+++GO:0051013///microtubule severing+++GO:0051301///cell division 74189 74189 'Phactr3' mRNA 6 12 21 0.11 0.21 0.35 0.04 0.04 0.02 0.223333333 0.033333333 3 2 2 13 2.333333333 0.017608022 -2.51273301 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016363///nuclear matrix GO:0003779///actin binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0008157///protein phosphatase 1 binding+++GO:0019888///protein phosphatase regulator activity GO:0030036///actin cytoskeleton organization+++GO:0043086///negative regulation of catalytic activity+++GO:0050790///regulation of catalytic activity 74190 74190 'Exoc3l4' mRNA 181 209 248 2.99 3.37 4.32 3.62 2.52 2.61 3.56 2.916666667 247 169 174 212.6666667 196.6666667 0.621817386 -0.134226029 GO:0000145///exocyst GO:0000149///SNARE binding GO:0006887///exocytosis+++GO:0051601///exocyst localization 74191 74191 'P2ry13' mRNA 67 77 66 1.48 1.67 1.54 11.14 10.04 10.87 1.563333333 10.68333333 582 512 550 70 548 4.44E-73 2.957448907 04080///Neuroactive ligand-receptor interaction GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0071407///cellular response to organic cyclic compound 74192 74192 'Arpc5l' mRNA 1240 1167 1119 57.66 54.18 55.26 58.21 61.6 60.3 55.7 60.03666667 1429 1472 1430 1175.333333 1443.666667 6.11E-04 0.285985667 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0015629///actin cytoskeleton+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0016477///cell migration+++GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation 74194 74194 'Rnd3' mRNA 141 149 198 2.75 2.86 4.1 9.48 10.13 8.79 3.236666667 9.466666667 559 583 502 162.6666667 548 1.03E-25 1.734174043 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0016477///cell migration+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization 74195 74195 'Elp3' mRNA 1295 1214 1328 24.82 22.84 27 20.08 18.7 17.8 24.88666667 18.86 1210 1095 1034 1279 1113 0.034587215 -0.215701012 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033588///Elongator holoenzyme complex "GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0008080///N-acetyltransferase activity+++GO:0008607///phosphorylase kinase regulator activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0001764///neuron migration+++GO:0002098///tRNA wobble uridine modification+++GO:0002926///tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0008033///tRNA processing+++GO:0030335///positive regulation of cell migration+++GO:0050790///regulation of catalytic activity 74196 74196 'Ttc27' mRNA 189 256 205 4.19 5.55 4.61 4.26 4.41 4.7 4.783333333 4.456666667 239 243 248 216.6666667 243.3333333 0.455216202 0.157962861 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74197 74197 'Gtf2e1' mRNA 428 470 439 7.58 8.22 8.18 8.36 7.2 7.17 7.993333333 7.576666667 543 456 451 445.6666667 483.3333333 0.504290272 0.1038502 03022///Basal transcription factors+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005673///transcription factor TFIIE complex+++GO:0005829///cytosol+++GO:0097550///transcriptional preinitiation complex GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0046872///metal ion binding GO:0001113///transcriptional open complex formation at RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter 74198 74198 'Dtx2' mRNA 440 459 438 9.96 9.9 10.23 9.99 10.05 10.71 10.03 10.25 522 517 546 445.6666667 528.3333333 0.064217873 0.233944718 04330///Notch signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination 74199 74199 'Vit' mRNA 346 413 299 7.03 8.23 6.45 8.74 9.35 9.29 7.236666667 9.126666667 494 517 510 352.6666667 507 1.48E-04 0.517171771 GO:0005576///extracellular region+++GO:0005614///interstitial matrix+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005539///glycosaminoglycan binding GO:0007399///nervous system development+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0021510///spinal cord development+++GO:0030198///extracellular matrix organization 74200 74200 'Khdc4' mRNA 1302 1345 1327 23.81 24.18 25.73 22.79 22.43 23 24.57333333 22.74 1434 1378 1401 1324.666667 1404.333333 0.464194178 0.0716009 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0005515///protein binding GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing 74201 74201 'Cep97' mRNA 309 340.31 324 3.53 4.53 4.03 3.3 2.37 3.49 4.03 3.053333333 266 218 226 324.4366667 236.6666667 0.00339016 -0.468302758 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902018///negative regulation of cilium assembly 74202 74202 'Fblim1' mRNA 1566 1599 1335 28.06 28.31 25.4 32.62 30.75 29.85 27.25666667 31.07333333 2099 1929 1858 1500 1962 1.29E-06 0.377886403 GO:0001650///fibrillar center+++GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030054///cell junction+++GO:0071944///cell periphery GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0008360///regulation of cell shape+++GO:0033623///regulation of integrin activation+++GO:0098609///cell-cell adhesion 74203 74203 'Eif4enif1' mRNA 1602 1663 1588.45 24.21 24.7 25.55 9.67 9.26 8.98 24.82 9.303333333 730.9 680 661.32 1617.816667 690.74 2.62E-50 -1.240927512 GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle GO:0003729///mRNA binding+++GO:0005049///nuclear export signal receptor activity+++GO:0005515///protein binding+++GO:0019900///kinase binding GO:0006417///regulation of translation+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0017148///negative regulation of translation+++GO:0019827///stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0045665///negative regulation of neuron differentiation+++GO:0048255///mRNA stabilization+++GO:0051168///nuclear export+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:1905618///positive regulation of miRNA mediated inhibition of translation 74204 74204 'Xpo6' mRNA 1246 1402 1130 18.93 19.97 18.5 11.82 11.48 10.76 19.13333333 11.35333333 847 799 729 1259.333333 791.6666667 6.47E-13 -0.678872396 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005049///nuclear export signal receptor activity+++GO:0031267///small GTPase binding GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport 74205 74205 'Acsl3' mRNA 6494.68 6805.84 3236.79 90.8 93.61 48.34 22.27 39.48 36.65 77.58333333 32.8 1824.88 3167.75 2911.82 5512.436667 2634.816667 0.007190246 -1.055137041 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04146///Peroxisome+++04216///Ferroptosis+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005811///lipid droplet+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0047676///arachidonate-CoA ligase activity GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007420///brain development+++GO:0007584///response to nutrient+++GO:0014070///response to organic cyclic compound+++GO:0030182///neuron differentiation+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:0044539///long-chain fatty acid import+++GO:0051047///positive regulation of secretion+++GO:2001247///positive regulation of phosphatidylcholine biosynthetic process 74206 74206 'Sipa1l3' mRNA 834.08 691.2 711.31 6.38 5.14 5.71 3.54 3.36 3.77 5.743333333 3.556666667 570.3 503 551 745.53 541.4333333 4.64E-05 -0.473724669 04015///Rap1 signaling pathway GO:0001725///stress fiber+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0045177///apical part of cell+++GO:0061689///tricellular tight junction GO:0005096///GTPase activator activity GO:0001654///eye development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0003382///epithelial cell morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090162///establishment of epithelial cell polarity+++GO:0090630///activation of GTPase activity 74211 74211 '1700017B05Rik' mRNA 596 577 513 6.41 6.13 5.88 13.22 14.61 13.8 6.14 13.87666667 1415 1524 1429 562 1456 8.59E-51 1.36435902 GO:0005829///cytosol GO:0003674///molecular_function GO:0008150///biological_process 74213 74213 'Rbm26' mRNA 1743 1741 1496 17.78 17.43 15.73 15.85 13.72 14.05 16.98 14.54 1788 1543 1547 1660 1626 0.714462006 -0.040284797 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding GO:0006397///mRNA processing+++GO:0010923///negative regulation of phosphatase activity 74218 74218 '1700016H13Rik' mRNA 2 0 0 0.14 0 0 0.12 0 0.44 0.046666667 0.186666667 2 0 7 0.666666667 3 0.408230559 2.174371156 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74229 74229 'Paqr8' mRNA 2503 2639 2521 24.84 25.83 26.49 11.04 12.02 10.85 25.72 11.30333333 1280 1368 1216 2554.333333 1288 1.03E-38 -0.99929701 05207///Chemical carcinogenesis - receptor activation GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003707///steroid hormone receptor activity+++GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0048477///oogenesis+++GO:0048545///response to steroid hormone 74230 74230 '1700016K19Rik' mRNA 257 273 46 18.29 19.28 3.48 0.56 1.02 1.6 13.68333333 1.06 9 16 25 192 16.66666667 4.11E-05 -3.501897936 GO:0005575///cellular_component GO:0005515///protein binding GO:0016598///protein arginylation 74237 74237 'Tubgcp2' mRNA 709.79 721.72 769.02 12.68 12.6 14.56 10.01 9.91 10.25 13.28 10.05666667 647.73 625 646.8 733.51 639.8433333 0.071180736 -0.211450178 GO:0000922///spindle pole+++GO:0000923///equatorial microtubule organizing center+++GO:0000930///gamma-tubulin complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0008275///gamma-tubulin small complex GO:0043015///gamma-tubulin binding+++GO:0051011///microtubule minus-end binding GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0001764///neuron migration+++GO:0007020///microtubule nucleation+++GO:0007420///brain development+++GO:0031122///cytoplasmic microtubule organization+++GO:0051225///spindle assembly+++GO:0051321///meiotic cell cycle 74238 74238 'Mterf2' mRNA 385.68 417.13 356.45 8.42 9.73 9.36 4.8 4.57 3.55 9.17 4.306666667 249.78 239.88 180.86 386.42 223.5066667 5.09E-07 -0.804111259 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0006393///termination of mitochondrial transcription" 74239 74239 'Iqce' mRNA 769 818 800 8.87 9.34 9.94 5.23 4.64 5.22 9.383333333 5.03 509 451 503 795.6666667 487.6666667 2.09E-11 -0.719493593 04340///Hedgehog signaling pathway GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0098797///plasma membrane protein complex GO:0005515///protein binding GO:0035108///limb morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II 74241 74241 'Chpf' mRNA 831 856 535 14.68 14.86 10.04 13.43 12.36 12.53 13.19333333 12.77333333 873 784 789 740.6666667 815.3333333 0.396135048 0.135189307 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane "GO:0005515///protein binding+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0050510///N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity" GO:0030206///chondroitin sulfate biosynthetic process 74243 74243 'Slx4ip' mRNA 176 199 160 1.82 2.04 1.69 1.51 1.22 1.26 1.85 1.33 175 126.01 132 178.3333333 144.3366667 0.166825079 -0.316655028 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74244 74244 'Atg7' mRNA 666.96 650.55 651.4 11.12 10.78 11.61 15.95 15.26 14.6 11.17 15.27 1070.94 995.5 956.31 656.3033333 1007.583333 2.55E-10 0.60618368 04136///Autophagy - other+++04140///Autophagy - animal+++04216///Ferroptosis+++04613///Neutrophil extracellular trap formation GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0030424///axon+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0019778///Atg12 activating enzyme activity+++GO:0019779///Atg8 activating enzyme activity+++GO:0042803///protein homodimerization activity GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0001889///liver development+++GO:0006497///protein lipidation+++GO:0006501///C-terminal protein lipidation+++GO:0006914///autophagy+++GO:0006995///cellular response to nitrogen starvation+++GO:0006996///organelle organization+++GO:0007005///mitochondrion organization+++GO:0007568///aging+++GO:0007628///adult walking behavior+++GO:0009267///cellular response to starvation+++GO:0009749///response to glucose+++GO:0009791///post-embryonic development+++GO:0010508///positive regulation of autophagy+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0021860///pyramidal neuron development+++GO:0021955///central nervous system neuron axonogenesis+++GO:0021987///cerebral cortex development+++GO:0030163///protein catabolic process+++GO:0031175///neuron projection development+++GO:0031396///regulation of protein ubiquitination+++GO:0031401///positive regulation of protein modification process+++GO:0031667///response to nutrient levels+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032446///protein modification by small protein conjugation+++GO:0034614///cellular response to reactive oxygen species+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0039521///suppression by virus of host autophagy+++GO:0039689///negative stranded viral RNA replication+++GO:0042594///response to starvation+++GO:0042752///regulation of circadian rhythm+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0044805///late nucleophagy+++GO:0045732///positive regulation of protein catabolic process+++GO:0048511///rhythmic process+++GO:0050765///negative regulation of phagocytosis+++GO:0050877///nervous system process+++GO:0051607///defense response to virus+++GO:0055013///cardiac muscle cell development+++GO:0060284///regulation of cell development+++GO:0060548///negative regulation of cell death+++GO:0061024///membrane organization+++GO:0061684///chaperone-mediated autophagy+++GO:0070257///positive regulation of mucus secretion+++GO:0071315///cellular response to morphine+++GO:0071455///cellular response to hyperoxia+++GO:0075044///autophagy of host cells involved in interaction with symbiont+++GO:0080144///amino acid homeostasis+++GO:0090155///negative regulation of sphingolipid biosynthetic process+++GO:0090156///cellular sphingolipid homeostasis+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:1901214///regulation of neuron death+++GO:1902617///response to fluoride+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1903706///regulation of hemopoiesis+++GO:2000619///negative regulation of histone H4-K16 acetylation 74245 74245 'Ctbs' mRNA 331.88 354 314.5 7.15 7.4 6.9 10.26 9.09 9.71 7.15 9.686666667 542.9 481.78 472.98 333.46 499.22 8.00E-06 0.570164335 GO:0005764///lysosome "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004568///chitinase activity+++GO:0008061///chitin binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process 74246 74246 'Gale' mRNA 348 303 282 13.81 11.86 12.19 24.31 26.59 27.16 12.62 26.02 689 733 742 311 721.3333333 1.28E-23 1.204620496 00052///Galactose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005829///cytosol GO:0003974///UDP-N-acetylglucosamine 4-epimerase activity+++GO:0003978///UDP-glucose 4-epimerase activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0005975///carbohydrate metabolic process+++GO:0006012///galactose metabolic process+++GO:0019388///galactose catabolic process+++GO:0033499///galactose catabolic process via UDP-galactose+++GO:0061623///glycolytic process from galactose 74249 74249 'Lrrc2' mRNA 6.61 12.79 13.36 0.1 0.18 0.21 0.07 0.05 0.06 0.163333333 0.06 5.04 4.07 4.84 10.92 4.65 0.215189584 -1.274500256 GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0004722///protein serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0007165///signal transduction+++GO:1990830///cellular response to leukemia inhibitory factor 74251 74251 'Ankrd9' mRNA 250 256 234 9.41 9.38 9.24 7.16 6.76 8.21 9.343333333 7.376666667 218 204 239 246.6666667 220.3333333 0.369441715 -0.173697899 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0031466///Cul5-RING ubiquitin ligase complex "GO:0016787///hydrolase activity+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006878///cellular copper ion homeostasis+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 74252 74252 'Armc1' mRNA 1065 1172 1062 15.14 16.3 16.12 16.15 14.66 15.36 15.85333333 15.39 1285 1139 1186 1099.666667 1203.333333 0.227592341 0.117994624 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0046872///metal ion binding GO:0048312///intracellular distribution of mitochondria 74253 74253 'Klrg2' mRNA 61.13 64.05 29.95 0.54 0.67 0.24 0.47 0.89 0.63 0.483333333 0.663333333 46.11 75.06 64.2 51.71 61.79 0.567652346 0.270633065 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0030246///carbohydrate binding GO:0008150///biological_process 74254 74254 'Gpn1' mRNA 890.89 866.26 974.64 18.6 18.05 22.54 15.76 17.9 15.57 19.73 16.41 822.34 917.71 797.33 910.5966667 845.7933333 0.360185568 -0.12055205 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity 74255 74255 'Smu1' mRNA 2242 2464 2240 37.41 40.45 39.64 39.18 35.81 37.18 39.16666667 37.39 2702 2412 2483 2315.333333 2532.333333 0.129164494 0.117178811 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome GO:0003674///molecular_function "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 74256 74256 'Cyld' mRNA 2776.39 2796.29 2868.79 18.01 17.83 19.78 8.96 8.37 8.62 18.54 8.65 1566.4 1433.46 1463.68 2813.823333 1487.846667 2.67E-37 -0.933587913 04013///MAPK signaling pathway - fly+++04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++04622///RIG-I-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0097542///ciliary tip GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070064///proline-rich region binding+++GO:1990380///Lys48-specific deubiquitinase activity "GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007346///regulation of mitotic cell cycle+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0016579///protein deubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043369///CD4-positive or CD8-positive, alpha-beta T cell lineage commitment+++GO:0043393///regulation of protein binding+++GO:0045087///innate immune response+++GO:0045577///regulation of B cell differentiation+++GO:0045581///negative regulation of T cell differentiation+++GO:0045582///positive regulation of T cell differentiation+++GO:0046329///negative regulation of JNK cascade+++GO:0048872///homeostasis of number of cells+++GO:0050727///regulation of inflammatory response+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0060544///regulation of necroptotic process+++GO:0070266///necroptotic process+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1901026///ripoptosome assembly involved in necroptotic process+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:1902017///regulation of cilium assembly+++GO:1903753///negative regulation of p38MAPK cascade+++GO:1903829///positive regulation of cellular protein localization+++GO:1990108///protein linear deubiquitination+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001242///regulation of intrinsic apoptotic signaling pathway" 74257 74257 'Tspan17' mRNA 946 1053 819 36.81 40.33 34.57 68.07 77.01 71.91 37.23666667 72.33 1985 2188 2015 939.3333333 2062.666667 9.28E-38 1.127936066 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0019899///enzyme binding GO:0051604///protein maturation+++GO:0072594///establishment of protein localization to organelle+++GO:0072659///protein localization to plasma membrane 74264 74264 'Rnf138rt1' mRNA 7 10 13 0.36 0.51 0.71 0 0.05 0.05 0.526666667 0.033333333 0 1 1 10 0.666666667 0.008750887 -3.92430275 GO:0005575///cellular_component+++GO:0035861///site of double-strand break GO:0003674///molecular_function+++GO:0003697///single-stranded DNA binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000724///double-strand break repair via homologous recombination+++GO:0008150///biological_process+++GO:0010792///DNA double-strand break processing involved in repair via single-strand annealing+++GO:0016567///protein ubiquitination 74268 74268 'Aven' mRNA 19 21 24 0.98 1.08 1.41 2.26 1.03 1.3 1.156666667 1.53 48 23 29 21.33333333 33.33333333 0.268243449 0.621813366 GO:0012505///endomembrane system+++GO:0016020///membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0043066///negative regulation of apoptotic process 74270 74270 'Usp20' mRNA 2671 2731 2860 34.6 34.81 39.32 15.13 14.25 13.3 36.24333333 14.22666667 1344 1238 1144 2754 1242 5.45E-45 -1.163801343 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0001664///G protein-coupled receptor binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006897///endocytosis+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016579///protein deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination 74276 74276 'Cldnd2' mRNA 5 7 6 0.31 0.51 0.44 0.37 0.44 0.34 0.42 0.383333333 5 6 5 6 5.333333333 0.887233713 -0.180038296 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 74277 74277 'Chic2' mRNA 220 244 128 4.8 5.24 2.96 3.17 3.05 3.9 4.333333333 3.373333333 167 157 199 197.3333333 174.3333333 0.524739975 -0.178659021 GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function GO:0006893///Golgi to plasma membrane transport 74281 74281 'Spatc1' mRNA 2 1 3 0.09 0.05 0.15 0.04 0 0 0.096666667 0.013333333 1 0 0 2 0.333333333 0.370649537 -2.511780517 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding GO:0008150///biological_process 74287 74287 'Kcmf1' mRNA 293 309 259 4.95 5.11 4.63 6.15 5.95 5.49 4.896666667 5.863333333 421 398 364 287 394.3333333 0.001735006 0.448579757 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0045202///synapse GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0099536///synaptic signaling 74288 74288 'Spem1' mRNA 4 2 3 0.25 0.12 0.2 0.05 0 0.11 0.19 0.053333333 1 0 2 3 1 0.455216202 -1.603033423 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007291///sperm individualization+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility 74302 74302 'Mtmr3' mRNA 980 953 946 9.24 8.81 9.44 8 7.41 7.79 9.163333333 7.733333333 976 887 923 959.6666667 928.6666667 0.605955856 -0.06010992 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04140///Autophagy - animal GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0019903///protein phosphatase binding+++GO:0046872///metal ion binding+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity" GO:0006470///protein dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0010506///regulation of autophagy+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042149///cellular response to glucose starvation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0060304///regulation of phosphatidylinositol dephosphorylation+++GO:1904562///phosphatidylinositol 5-phosphate metabolic process+++GO:2000785///regulation of autophagosome assembly 74306 74306 'Prss46' mRNA 1 0 2 0.05 0 0.1 1.18 0.69 0.87 0.05 0.913333333 28 16 20 1 21.33333333 9.29E-05 4.389091612 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 74307 74307 '1700092M07Rik' mRNA 1 1 2 0.28 0.28 0.59 0.25 0.26 0.26 0.383333333 0.256666667 1 1 1 1.333333333 1 0.868860061 -0.441890762 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74309 74309 'Osbp2' mRNA 580 568 509 8.69 8.35 8.18 0.62 0.87 1.1 8.406666667 0.863333333 55 71 87 552.3333333 71 1.03E-65 -2.967986094 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0097440///apical dendrite GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0007286///spermatid development 74315 74315 'Rnf145' mRNA 2659 2804 1013 40.33 41.82 16.42 19.17 36.46 29.1 32.85666667 28.24333333 1456 2705 2137 2158.666667 2099.333333 0.975943699 -0.024652781 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 74316 74316 'Isca2' mRNA 1038 1009 1037 79.35 76.43 84.11 76.72 76.16 70.63 79.96333333 74.50333333 1146 1111 1022 1028 1093 0.508257099 0.075243273 GO:0005739///mitochondrion "GO:0005506///iron ion binding+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0016226///iron-sulfur cluster assembly+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer 74318 74318 'Hopx' mRNA 542 447 521 30.17 24.5 30.61 6.37 6.67 6.16 28.42666667 6.4 130 133 122 503.3333333 128.3333333 5.03E-36 -1.985956078 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001829///trophectodermal cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0008016///regulation of heart contraction+++GO:0016575///histone deacetylation+++GO:0030154///cell differentiation+++GO:0043393///regulation of protein binding+++GO:0043415///positive regulation of skeletal muscle tissue regeneration+++GO:0045596///negative regulation of cell differentiation+++GO:0048286///lung alveolus development+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0051155///positive regulation of striated muscle cell differentiation 74319 74319 'Mettl23' mRNA 477 474 430 29.41 28.84 28.02 25.05 25.58 26.33 28.75666667 25.65333333 470 466 476 460.3333333 470.6666667 0.886641694 0.021791549 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0008134///transcription factor binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0031072///heat shock protein binding GO:0032259///methylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050890///cognition 74320 74320 'Wdr33' mRNA 2667.83 2768.6 2511.71 35.87 35.6 34.98 28.64 27.49 27.49 35.48333333 27.87333333 2362.47 2208.55 2229.74 2649.38 2266.92 2.95E-04 -0.236025577 03015///mRNA surveillance pathway GO:0001650///fibrillar center+++GO:0005581///collagen trimer+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing 74322 74322 'Cxxc1' mRNA 1147 1122 1023 25.13 24.21 23.79 24.45 25.82 24.42 24.37666667 24.89666667 1283 1324 1241 1097.333333 1282.666667 0.014253707 0.215169379 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0035097///histone methyltransferase complex+++GO:0048188///Set1C/COMPASS complex GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051568///histone H3-K4 methylation" 74325 74325 'Cltb' mRNA 2648 2528 2531 66.84 62.84 67.78 76.27 86.73 79.44 65.82 80.81333333 3474 3857 3503 2569 3611.333333 7.95E-11 0.480136189 04142///Lysosome+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption+++05016///Huntington disease+++05100///Bacterial invasion of epithelial cells GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030118///clathrin coat+++GO:0030125///clathrin vesicle coat+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0030132///clathrin coat of coated pit+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0060170///ciliary membrane+++GO:0098835///presynaptic endocytic zone membrane+++GO:0099631///postsynaptic endocytic zone cytoplasmic component GO:0005198///structural molecule activity+++GO:0032050///clathrin heavy chain binding+++GO:0042277///peptide binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048268///clathrin coat assembly+++GO:0072583///clathrin-dependent endocytosis 74326 74326 'Hnrnpr' mRNA 2293 2393 2233 15.13 15.52 15.64 13.93 13.48 14.21 15.43 13.87333333 2432 2299 2400 2306.333333 2377 0.724229478 0.031922684 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0043679///axon terminus+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding GO:0007623///circadian rhythm+++GO:0043086///negative regulation of catalytic activity+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0061157///mRNA destabilization 74330 74330 'Dnajc14' mRNA 1798.15 1699.54 1649.29 22.44 20.88 21.8 23.55 21.71 23.22 21.70666667 22.82666667 2172.39 1954.83 2075.07 1715.66 2067.43 5.73E-04 0.25691723 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001664///G protein-coupled receptor binding+++GO:0050780///dopamine receptor binding GO:0008150///biological_process+++GO:0015031///protein transport 74334 74334 'Ranbp10' mRNA 589 562 498 6.09 5.72 5.46 6.13 5.95 5.66 5.756666667 5.913333333 682 646 611 549.6666667 646.3333333 0.056782898 0.22368463 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding+++GO:0048487///beta-tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0007166///cell surface receptor signaling pathway+++GO:0050790///regulation of catalytic activity 74335 74335 'Xrcc3' mRNA 212.49 194.67 188.86 4.82 4.34 4.54 4.4 3.38 3.92 4.566666667 3.9 222.89 167.41 192.29 198.6733333 194.1966667 0.863090843 -0.04509594 03440///Homologous recombination GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0033065///Rad51C-XRCC3 complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0000400///four-way junction DNA binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008821///crossover junction endodeoxyribonuclease activity GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010033///response to organic substance+++GO:0010824///regulation of centrosome duplication+++GO:0036297///interstrand cross-link repair+++GO:0045003///double-strand break repair via synthesis-dependent strand annealing+++GO:0071140///resolution of mitotic recombination intermediates+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0090656///t-circle formation+++GO:0090737///telomere maintenance via telomere trimming 74337 74337 'Palm3' mRNA 345 388 330.55 7.64 8.56 7.77 1.08 0.86 0.7 7.99 0.88 55 43 35.12 354.5166667 44.37333333 1.87E-47 -3.010040519 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0008063///Toll signaling pathway+++GO:0032496///response to lipopolysaccharide 74338 74338 'Slc6a19' mRNA 2 1 0 0.03 0.01 0 0.18 0.27 0.37 0.013333333 0.273333333 14 20 28 1 20.66666667 1.26E-04 4.370468203 04974///Protein digestion and absorption+++04978///Mineral absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane GO:0005515///protein binding+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0006865///amino acid transport+++GO:0007584///response to nutrient+++GO:0015804///neutral amino acid transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport 74340 74340 'Ahcyl2' mRNA 1621 1790 1642 17.86 19.37 19.27 11.91 12.14 11.62 18.83333333 11.89 1247 1239 1182 1684.333333 1222.666667 2.54E-09 -0.473547791 00270///Cysteine and methionine metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle GO:0004013///adenosylhomocysteinase activity+++GO:0016787///hydrolase activity GO:0006730///one-carbon metabolic process+++GO:0033353///S-adenosylmethionine cycle 74342 74342 'Lrrtm1' mRNA 233 232 184 1.46 1.89 1.03 0.31 0.34 0.5 1.46 0.383333333 35 39 44 216.3333333 39.33333333 9.12E-25 -2.466090979 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0031012///extracellular matrix+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099060///integral component of postsynaptic specialization membrane GO:0002091///negative regulation of receptor internalization+++GO:0007626///locomotory behavior+++GO:0035418///protein localization to synapse+++GO:0035640///exploration behavior+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0060291///long-term synaptic potentiation+++GO:0099151///regulation of postsynaptic density assembly+++GO:1905606///regulation of presynapse assembly 74343 74343 'Crtc2' mRNA 1203 1295 806 24.19 24.5 17.37 13.19 15.8 14.61 22.02 14.53333333 743 875 811 1101.333333 809.6666667 0.00118389 -0.444474299 04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008140///cAMP response element binding protein binding GO:0006094///gluconeogenesis+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0042593///glucose homeostasis+++GO:0043970///histone H3-K9 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051289///protein homotetramerization+++GO:1901998///toxin transport 74347 74347 'Meak7' mRNA 639 756 702 11.22 13.21 12.8 7.02 6.16 6.06 12.41 6.413333333 476 398 386 699 420 1.35E-09 -0.748699529 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0003674///molecular_function GO:0030334///regulation of cell migration+++GO:0031667///response to nutrient levels+++GO:0031929///TOR signaling+++GO:0032868///response to insulin+++GO:0042127///regulation of cell proliferation+++GO:0043200///response to amino acid+++GO:0150032///positive regulation of protein localization to lysosome+++GO:1903204///negative regulation of oxidative stress-induced neuron death 74349 74349 'Fam160a2' mRNA 1727 1635 1523 8.28 7.7 7.75 6.14 6.29 5.78 7.91 6.07 1480 1478 1351 1628.333333 1436.333333 0.022651643 -0.191538128 GO:0005829///cytosol+++GO:0070695///FHF complex GO:0003674///molecular_function GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0045022///early endosome to late endosome transport+++GO:1905719///protein localization to perinuclear region of cytoplasm 74351 74351 'Ddx23' mRNA 543 503 441 9.7 8.78 8.37 6.94 6.05 7.03 8.95 6.673333333 445 378 437 495.6666667 420 0.067990012 -0.249066475 03040///Spliceosome GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005682///U5 snRNP+++GO:0005730///nucleolus+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071013///catalytic step 2 spliceosome GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity "GO:0000398///mRNA splicing, via spliceosome" 74352 74352 'Zfp84' mRNA 410 483 417.97 3.82 4.42 4.13 4.21 4.24 3.72 4.123333333 4.056666667 521 512.18 446 436.99 493.06 0.261372048 0.164263072 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0019216///regulation of lipid metabolic process" 74354 74354 'Lrguk' mRNA 635 647 565 8.74 8.82 8.61 0.96 0.76 0.79 8.723333333 0.836666667 85 68 73 615.6666667 75.33333333 2.29E-84 -3.04149027 GO:0001669///acrosomal vesicle+++GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004385///guanylate kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0030154///cell differentiation+++GO:0035082///axoneme assembly+++GO:0046037///GMP metabolic process+++GO:0046710///GDP metabolic process 74355 74355 'Smchd1' mRNA 1067 1128 1039 7.99 8.31 8.26 7.7 6.93 6.84 8.186666667 7.156666667 1184 1042 1018 1078 1081.333333 0.950261429 -0.007800711 "GO:0000781///chromosome, telomeric region+++GO:0001740///Barr body+++GO:0005694///chromosome+++GO:0035861///site of double-strand break" GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042803///protein homodimerization activity GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0043584///nose development+++GO:0045739///positive regulation of DNA repair+++GO:0051276///chromosome organization+++GO:0060820///inactivation of X chromosome by heterochromatin assembly+++GO:0060821///inactivation of X chromosome by DNA methylation+++GO:0070868///heterochromatin organization involved in chromatin silencing+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 74356 74356 '4931428F04Rik' mRNA 170.06 228.26 176.25 2.86 3.83 3.39 2.09 2.84 2.84 3.36 2.59 129.26 169.19 163.42 191.5233333 153.9566667 0.164306027 -0.322833215 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74359 74359 '4931414P19Rik' mRNA 205 195 148 3.81 3.8 2.8 2.4 2.67 2.28 3.47 2.45 141 149 137 182.6666667 142.3333333 0.093465645 -0.365980875 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0048856///anatomical structure development 74360 74360 'Cep57' mRNA 563.34 592.74 573.7 11.88 12.35 12.74 11.53 12.32 11.35 12.32333333 11.73333333 624.92 644.19 585.31 576.5933333 618.14 0.517206705 0.088900004 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0017134///fibroblast growth factor binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043015///gamma-tubulin binding GO:0007286///spermatid development+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0034453///microtubule anchoring+++GO:0051260///protein homooligomerization 74361 74361 '4931429L15Rik' mRNA 3 4 0 0.09 0.11 0 0 0.03 0.03 0.066666667 0.02 0 1 1 2.333333333 0.666666667 0.512668052 -1.77386877 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74362 74362 'Spag17' mRNA 6 7 7 0.04 0.05 0.05 0.02 0.05 0.01 0.046666667 0.026666667 3 8 2 6.666666667 4.333333333 0.64476352 -0.628184153 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:1990716///axonemal central apparatus GO:0005515///protein binding GO:0003351///epithelial cilium movement+++GO:0030030///cell projection organization+++GO:1904158///axonemal central apparatus assembly 74365 74365 'Lonrf3' mRNA 189 226 173 1.34 1.59 1.31 2.88 1.99 2.92 1.413333333 2.596666667 465 315 456 196 412 1.28E-09 1.06089081 GO:0046872///metal ion binding 74369 74369 'Mei1' mRNA 241 235 265 4.12 3.96 4.82 0.18 0.18 0.17 4.3 0.176666667 12 12 11 247 11.66666667 6.41E-44 -4.419474458 GO:0000212///meiotic spindle organization+++GO:0000237///leptotene+++GO:0007127///meiosis I+++GO:0007141///male meiosis I+++GO:0007276///gamete generation+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0045141///meiotic telomere clustering+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle 74370 74370 'Rptor' mRNA 734 691 407 5.7 5.4 4.08 3.61 3.08 3.55 5.06 3.413333333 447 430 493 610.6666667 456.6666667 0.015805905 -0.419633222 04136///Autophagy - other+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++04714///Thermogenesis+++04910///Insulin signaling pathway+++05131///Shigellosis+++05206///MicroRNAs in cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030425///dendrite+++GO:0031931///TORC1 complex+++GO:0043025///neuronal cell body "GO:0001002///RNA polymerase III type 1 promoter sequence-specific DNA binding+++GO:0001003///RNA polymerase III type 2 promoter sequence-specific DNA binding+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0001156///TFIIIC-class transcription factor complex binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0030295///protein kinase activator activity+++GO:0030674///protein binding, bridging+++GO:0044877///protein-containing complex binding+++GO:0071889///14-3-3 protein binding" GO:0001558///regulation of cell growth+++GO:0001932///regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008361///regulation of cell size+++GO:0009267///cellular response to starvation+++GO:0009410///response to xenobiotic stimulus+++GO:0010506///regulation of autophagy+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0031669///cellular response to nutrient levels+++GO:0031929///TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0032147///activation of protein kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035176///social behavior+++GO:0038202///TORC1 signaling+++GO:0042325///regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0046676///negative regulation of insulin secretion+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle 74374 74374 'Clec16a' mRNA 2803.43 2788.52 2415.9 38.52 38.05 35.56 26.69 29.75 25.69 37.37666667 27.37666667 2253.66 2386.72 2146.99 2669.283333 2262.456667 9.89E-04 -0.247408422 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0036020///endolysosome membrane GO:0005515///protein binding GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0009267///cellular response to starvation+++GO:0016197///endosomal transport+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1901096///regulation of autophagosome maturation+++GO:1901097///negative regulation of autophagosome maturation+++GO:1901098///positive regulation of autophagosome maturation+++GO:1901525///negative regulation of mitophagy+++GO:1904263///positive regulation of TORC1 signaling+++GO:1904766///negative regulation of macroautophagy by TORC1 signaling 74375 74375 'Gcc1' mRNA 621 635 668 8.09 8.13 9.23 8 8.2 8.18 8.483333333 8.126666667 707 708 700 641.3333333 705 0.330224762 0.122950155 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 74376 74376 'Myo18b' mRNA 25 48 29 0.16 0.3 0.2 0.06 0.14 0.13 0.22 0.11 11 24 22 34 19 0.142368341 -0.839520258 GO:0016459///myosin complex+++GO:0016461///unconventional myosin complex+++GO:0030018///Z disc+++GO:0031941///filamentous actin GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0048739///cardiac muscle fiber development+++GO:0055013///cardiac muscle cell development 74377 74377 'Hsf2bp' mRNA 22 19 12 0.72 0.49 0.46 0.97 0.64 0.53 0.556666667 0.713333333 33 24 19 17.66666667 25.33333333 0.426679679 0.513207343 GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0007283///spermatogenesis+++GO:1990918///double-strand break repair involved in meiotic recombination 74383 74383 'Ubap2l' mRNA 3303 3650 3413 44.77 48.53 49.12 51 47.17 49.63 47.47333333 49.26666667 4302 3899 4056 3455.333333 4085.666667 6.11E-04 0.229087746 GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0031519///PcG protein complex GO:0003674///molecular_function GO:0007339///binding of sperm to zona pellucida+++GO:0034063///stress granule assembly+++GO:0061484///hematopoietic stem cell homeostasis 74385 74385 'Ap5m1' mRNA 590.21 624.15 550.09 9.11 8.87 9.28 7.9 8.19 7.48 9.086666667 7.856666667 587.11 583.11 556.07 588.15 575.43 0.780031337 -0.041624132 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0031902///late endosome membrane GO:0015031///protein transport+++GO:0016197///endosomal transport 74386 74386 'Rmi1' mRNA 434 452 393 6.79 6.94 6.4 7.25 8 7.16 6.71 7.47 536 555 496 426.3333333 529 0.016913863 0.30171545 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0031422///RecQ helicase-Topo III complex GO:0000166///nucleotide binding+++GO:0003674///molecular_function GO:0000712///resolution of meiotic recombination intermediates+++GO:0000724///double-strand break repair via homologous recombination+++GO:0002021///response to dietary excess+++GO:0002023///reduction of food intake in response to dietary excess+++GO:0006260///DNA replication+++GO:0009749///response to glucose+++GO:0035264///multicellular organism growth+++GO:0042593///glucose homeostasis 74387 74387 '4932438H23Rik' mRNA 7 9 8 0.31 0.24 0.18 0.48 0.7 0.92 0.243333333 0.7 15 21 29 8 21.66666667 0.041335221 1.429438874 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74388 74388 'Dpp8' mRNA 1237 1200 578 13.93 13.34 6.97 7.64 8.71 9.08 11.41333333 8.476666667 772 867 904 1005 847.6666667 0.56368142 -0.239767212 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 74392 74392 'Specc1l' mRNA 2047 2102 1759 17.9 18.06 16.32 11.49 12.03 12.05 17.42666667 11.85666667 1514 1548 1538 1969.333333 1533.333333 1.11E-06 -0.369419895 GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0005921///gap junction+++GO:0015629///actin cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0030054///cell junction+++GO:0031941///filamentous actin GO:0008013///beta-catenin binding GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:0030036///actin cytoskeleton organization+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0034332///adherens junction organization+++GO:0036032///neural crest cell delamination+++GO:0051301///cell division+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060325///face morphogenesis+++GO:0061713///anterior neural tube closure 74393 74393 'Map10' mRNA 395 462 349 6.05 6.96 5.67 2.21 2.87 2.53 6.226666667 2.536666667 166 211 184 402 187 7.69E-12 -1.109792538 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0030496///midbody+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone GO:0008017///microtubule binding GO:0000226///microtubule cytoskeleton organization+++GO:0007049///cell cycle+++GO:0031122///cytoplasmic microtubule organization+++GO:0032467///positive regulation of cytokinesis+++GO:0032886///regulation of microtubule-based process+++GO:0051256///mitotic spindle midzone assembly+++GO:0051301///cell division 74399 74399 'Duxf3' mRNA 3 1 2 0.03 0.01 0.02 0.01 0 0.02 0.02 0.01 1 0 2 2 1 0.703304273 -1.019309973 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030182///neuron differentiation 74400 74400 'Zfp819' mRNA 21 26 12 0.51 0.59 0.32 0.02 0.02 0.07 0.473333333 0.036666667 1 1 3 19.66666667 1.666666667 3.33E-04 -3.557880555 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043065///positive regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated" 74405 74405 'Efhc2' mRNA 137 118 129 2.91 2.46 2.9 0.2 0.38 0.63 2.756666667 0.403333333 11 20 33 128 21.33333333 1.60E-13 -2.59479648 GO:0005874///microtubule+++GO:0005930///axoneme+++GO:0036064///ciliary basal body+++GO:0072686///mitotic spindle GO:0043014///alpha-tubulin binding GO:0000281///mitotic cytokinesis+++GO:0007052///mitotic spindle organization+++GO:0010975///regulation of neuron projection development+++GO:0060285///cilium-dependent cell motility+++GO:1990830///cellular response to leukemia inhibitory factor 74407 74407 'Ttc25' mRNA 526 474 478 10.47 9.38 10.2 1.68 1.14 1.58 10.01666667 1.466666667 95 66 90 492.6666667 83.66666667 6.74E-52 -2.571465894 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection+++GO:0097728///9+0 motile cilium+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0030324///lung development+++GO:0036158///outer dynein arm assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0090660///cerebrospinal fluid circulation 74409 74409 'Hyal6' mRNA 1 2 0 0.02 0.03 0 0 0 0 0.016666667 0 0 0 0 1 0 0.616323562 -2.415498512 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle "GO:0003674///molecular_function+++GO:0003824///catalytic activity+++GO:0004415///hyalurononglucosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0030214///hyaluronan catabolic process 74410 74410 'Ttll11' mRNA 12 27 15 0.18 0.39 0.23 0.15 0.09 0.13 0.266666667 0.123333333 12 7 10 18 9.666666667 0.240711177 -0.904927722 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation+++GO:0051013///microtubule severing 74411 74411 'Plpp6' mRNA 219.94 254.71 42.04 4.2 4.79 0.85 2.08 1.87 2.96 3.28 2.303333333 125.11 109.84 172.25 172.23 135.7333333 0.748070175 -0.324427521 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0042577///lipid phosphatase activity GO:0046839///phospholipid dephosphorylation 74412 74412 'Gle1' mRNA 1422 1615 1361 25.07 28.02 25.46 18.08 18.23 17.82 26.18333333 18.04333333 1180 1162 1126 1466 1156 2.77E-05 -0.352480661 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005643///nuclear pore+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0036064///ciliary basal body+++GO:0044614///nuclear pore cytoplasmic filaments GO:0000822///inositol hexakisphosphate binding+++GO:0005543///phospholipid binding+++GO:0031369///translation initiation factor binding+++GO:0042802///identical protein binding GO:0006406///mRNA export from nucleus+++GO:0006446///regulation of translational initiation+++GO:0006449///regulation of translational termination+++GO:0015031///protein transport+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 74413 74413 'Tc2n' mRNA 144.44 148.25 138.1 1.46 1.46 1.46 0.56 0.51 0.58 1.46 0.55 64.11 58.93 63.24 143.5966667 62.09333333 4.30E-07 -1.228471188 GO:0005634///nucleus 74414 74414 'Polr3c' mRNA 661 703 631 17.68 18.33 18.28 17.46 16.37 16.81 18.09666667 16.88 735 704 723 665 720.6666667 0.372156227 0.105182083 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity "GO:0002376///immune system process+++GO:0006351///transcription, DNA-templated+++GO:0032728///positive regulation of interferon-beta production+++GO:0032774///RNA biosynthetic process+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0051607///defense response to virus" 74419 74419 'Tktl2' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004802///transketolase activity+++GO:0016740///transferase activity+++GO:0030976///thiamine pyrophosphate binding+++GO:0046872///metal ion binding 74424 74424 'Tmc5' mRNA 8 5 1 0.11 0.07 0.02 0.05 0.04 0 0.066666667 0.03 4 3 0 4.666666667 2.333333333 0.585292461 -0.993454545 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008381///mechanosensitive ion channel activity GO:0006811///ion transport+++GO:0034220///ion transmembrane transport 74426 74426 '4933402D24Rik' mRNA 1 7 3 0.03 0.23 0.1 0.03 0.03 0 0.12 0.02 1 1 0 3.666666667 0.666666667 0.24684703 -2.46264624 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74427 74427 'Eaf1' mRNA 569 670 675 7.23 8.37 9.09 10.3 9.94 9.48 8.23 9.906666667 933.99 880.01 832 638 882 7.32E-05 0.452176697 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0016607///nuclear speck+++GO:0032783///ELL-EAF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045171///intercellular bridge GO:0003711///transcription elongation regulator activity+++GO:0008134///transcription factor binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 74430 74430 'Cfap20dc' mRNA 186 188 105 3.88 3.95 2.73 0.44 0.92 0.45 3.52 0.603333333 24 51 25 159.6666667 33.33333333 1.17E-11 -2.255132644 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74434 74434 'Sohlh2' mRNA 0 0 2 0 0 0.05 0.04 0.02 0 0.016666667 0.02 2 1 0 0.666666667 1 0.891853298 0.50247144 GO:0005634///nucleus+++GO:0005737///cytoplasm "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001545///primary ovarian follicle growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009994///oocyte differentiation+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis" 74435 74435 'Lrriq3' mRNA 79 66 67 1.65 1.45 1.66 0.47 0.8 0.56 1.586666667 0.61 22 36 21 70.66666667 26.33333333 1.80E-04 -1.432394356 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74438 74438 'Clvs1' mRNA 21.45 22.7 23.91 0.35 0.37 0.38 0.14 0.06 0.08 0.366666667 0.093333333 10.34 4 5.41 22.68666667 6.583333333 0.011320834 -1.816279691 GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane "GO:0008289///lipid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:1902936///phosphatidylinositol bisphosphate binding" GO:0007040///lysosome organization 74440 74440 'Cmip' mRNA 760 850 736 9.55 10.46 9.87 7.13 6.39 6.77 9.96 6.763333333 655 570 602 782 609 4.54E-04 -0.371922556 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function GO:0001701///in utero embryonic development 74442 74442 'Sgms2' mRNA 56 57 96 0.54 0.53 0.97 2.88 2.27 2.53 0.68 2.56 351 268 297 69.66666667 305.3333333 1.68E-19 2.107092866 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0002950///ceramide phosphoethanolamine synthase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0033188///sphingomyelin synthase activity+++GO:0047493///ceramide cholinephosphotransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0016310///phosphorylation+++GO:0030500///regulation of bone mineralization+++GO:0046513///ceramide biosynthetic process+++GO:1905373///ceramide phosphoethanolamine biosynthetic process 74443 74443 'P4htm' mRNA 690 707 666 22.1 22.48 22.68 11.41 10.54 10.74 22.42 10.89666667 411 367 373 687.6666667 383.6666667 1.49E-14 -0.854026121 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity" GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0045646///regulation of erythrocyte differentiation 74446 74446 'Slc9b1' mRNA 4 8 5 0.07 0.13 0.1 0.1 0.05 0.07 0.1 0.073333333 7 4 5 5.666666667 5.333333333 0.943644194 -0.098576467 GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0097228///sperm principal piece GO:0003674///molecular_function+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0007338///single fertilization+++GO:0030317///flagellated sperm motility+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 74448 74448 'Arl13a' mRNA 1 0 0 0.03 0 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0031514///motile cilium+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0097500///receptor localization to non-motile cilium+++GO:1905515///non-motile cilium assembly 74450 74450 'Pank2' mRNA 450.51 472.33 293.58 6.1 6.16 4.34 4.7 3.62 4.41 5.533333333 4.243333333 389.39 300.33 360.87 405.4733333 350.1966667 0.25628081 -0.216528295 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004594///pantothenate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0001525///angiogenesis+++GO:0007286///spermatid development+++GO:0009060///aerobic respiration+++GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070584///mitochondrion morphogenesis+++GO:0090207///regulation of triglyceride metabolic process+++GO:1904251///regulation of bile acid metabolic process 74451 74451 'Pgs1' mRNA 887 1014 546 21.67 24.39 14.15 21.05 28.93 27.67 20.07 25.88333333 991 1330 1261 815.6666667 1194 0.06477987 0.554007177 00564///Glycerophospholipid metabolism GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0008444///CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity+++GO:0016740///transferase activity GO:0006629///lipid metabolic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0032049///cardiolipin biosynthetic process+++GO:0046339///diacylglycerol metabolic process 74453 74453 'Cfap53' mRNA 119 87 85 3.64 2.62 2.75 0.19 0.16 0.14 3.003333333 0.163333333 7 6 5 97 6 1.03E-17 -4.024954306 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0034451///centriolar satellite+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097728///9+0 motile cilium+++GO:0097729///9+2 motile cilium GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0030317///flagellated sperm motility+++GO:0060271///cilium assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0090660///cerebrospinal fluid circulation 74455 74455 'Nsun6' mRNA 261.19 272.78 240.3 2.41 2.54 2.64 2.31 2.21 2.55 2.53 2.356666667 264.22 234.8 270.84 258.09 256.62 0.924011351 -0.020101767 GO:0005737///cytoplasm GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016428///tRNA (cytosine-5-)-methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0002946///tRNA C5-cytosine methylation+++GO:0030488///tRNA methylation+++GO:0032259///methylation 74463 74463 'Exoc3l2' mRNA 5 9 5 0.07 0.12 0.07 0.44 0.33 0.23 0.086666667 0.333333333 37 27 19 6.333333333 27.66666667 0.0016192 2.11718811 GO:0000145///exocyst+++GO:0005575///cellular_component GO:0000149///SNARE binding+++GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0006887///exocytosis+++GO:0051601///exocyst localization 74464 74464 'Zswim5' mRNA 265.55 328.93 262.27 1.81 2.35 2.12 0.77 0.6 0.74 2.093333333 0.703333333 123.62 100.43 127.96 285.5833333 117.3366667 2.81E-12 -1.298727065 GO:0031462///Cul2-RING ubiquitin ligase complex GO:0003674///molecular_function+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:1902667///regulation of axon guidance 74466 74466 'Mfsd13b' mRNA 22.52 38.54 23.59 0.62 1.06 0.69 0.99 0.98 1.26 0.79 1.076666667 41.86 40.34 50.99 28.21666667 44.39666667 0.164057149 0.652884105 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0051082///unfolded protein binding GO:0006457///protein folding+++GO:0008150///biological_process 74467 74467 'Pus10' mRNA 704 709 706 7.37 7.73 8.16 5.23 5.64 5.76 7.753333333 5.543333333 626 556 588 706.3333333 590 0.013796247 -0.272874145 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding+++GO:0070878///primary miRNA binding+++GO:0106029///tRNA pseudouridine synthase activity GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0031053///primary miRNA processing+++GO:0031119///tRNA pseudouridine synthesis 74469 74469 'Taf7l' mRNA 0 2 0 0 0.07 0 0.03 0.06 0.06 0.023333333 0.05 1 2 2 0.666666667 1.666666667 0.663821167 1.348222952 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm+++GO:0010369///chromocenter GO:0005515///protein binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0051123///RNA polymerase II preinitiation complex assembly 74470 74470 'Cep72' mRNA 46 26.08 30.02 0.59 0.34 0.43 0.93 0.48 0.72 0.453333333 0.71 66 40 57 34.03333333 54.33333333 0.128482403 0.662289341 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0042802///identical protein binding GO:0007051///spindle organization+++GO:0007099///centriole replication+++GO:0033566///gamma-tubulin complex localization+++GO:1904779///regulation of protein localization to centrosome 74471 74471 '4933440N22Rik' mRNA 6.63 10.77 2.11 0.18 0.28 0.06 0.02 0.4 0.18 0.173333333 0.2 0.86 16.84 7.4 6.503333333 8.366666667 0.813944686 0.383155207 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74472 74472 'Stpg3' mRNA 1 1 1 0.04 0.03 0.03 0.07 0.07 0.11 0.033333333 0.083333333 2 2 4 1 2.666666667 0.518549226 1.404737448 GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 74477 74477 '4933427D14Rik' mRNA 537 506 503 6.42 5.84 6.52 3.72 3.77 2.91 6.26 3.466666667 361 356 267 515.3333333 328 3.84E-06 -0.664270652 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0034451///centriolar satellite GO:0003674///molecular_function GO:0007099///centriole replication+++GO:0071539///protein localization to centrosome 74478 74478 'Snx29' mRNA 450.03 459.64 474 5.59 5.46 6.23 5.34 4.44 4.81 5.76 4.863333333 506 395 437 461.2233333 446 0.727961753 -0.063034359 GO:0003674///molecular_function+++GO:0035091///phosphatidylinositol binding GO:0008150///biological_process 74479 74479 'Snx11' mRNA 545 533 535 11.86 11.41 12.43 10.91 10.47 11.6 11.9 10.99333333 576 542 597 537.6666667 571.6666667 0.599047984 0.075949394 GO:0005768///endosome+++GO:0016020///membrane GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:1901981///phosphatidylinositol phosphate binding GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016050///vesicle organization 74480 74480 'Samd4' mRNA 163 167 145 1.15 1.21 1.07 2.1 1.43 1.97 1.143333333 1.833333333 346 239 308 158.3333333 297.6666667 8.39E-07 0.898216823 GO:0000932///P-body+++GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0030371///translation repressor activity GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0043488///regulation of mRNA stability+++GO:0045727///positive regulation of translation 74481 74481 'Batf2' mRNA 18 24 13 0.65 0.94 0.57 3.44 3.69 3.9 0.72 3.676666667 105 108 113 18.33333333 108.6666667 9.86E-14 2.562342498 05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0042832///defense response to protozoan+++GO:0043011///myeloid dendritic cell differentiation" 74482 74482 'Ifitm7' mRNA 0 1 0 0 0.08 0 0.07 0.07 0 0.026666667 0.046666667 1 1 0 0.333333333 0.666666667 0.863090843 0.881251873 GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane GO:0003674///molecular_function GO:0008285///negative regulation of cell proliferation+++GO:0009615///response to virus+++GO:0030336///negative regulation of cell migration+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0035458///cellular response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 74485 74485 'Lrrc71' mRNA 40.57 16.72 30.53 0.6 0.21 0.59 0.86 0.53 0.6 0.466666667 0.663333333 70.8 43.74 50.8 29.27333333 55.11333333 0.050264648 0.902214211 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74486 74486 'Osbpl10' mRNA 291.37 226.23 277.13 1.48 1.24 1.64 2.44 2.31 2.24 1.453333333 2.33 526.61 523.31 512.99 264.91 520.97 1.72E-11 0.960933808 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0001786///phosphatidylserine binding+++GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding GO:0006629///lipid metabolic process+++GO:0006869///lipid transport+++GO:0015918///sterol transport 74488 74488 'Lrrc15' mRNA 0 0 1 0 0 0.01 0.06 0.08 0.01 0.003333333 0.05 7 9 1 0.333333333 5.666666667 0.045215986 3.972239645 GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0001968///fibronectin binding+++GO:0005518///collagen binding+++GO:0043236///laminin binding GO:0030335///positive regulation of cell migration+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:1903077///negative regulation of protein localization to plasma membrane 74490 74490 'Mamstr' mRNA 144 133 120 3.12 3.04 2.61 1.89 2.79 2.35 2.923333333 2.343333333 121 158 134 132.3333333 137.6666667 0.863090843 0.049483379 GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010831///positive regulation of myotube differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II 74492 74492 'Kbtbd13' mRNA 5 9 1 0.09 0.16 0.02 0.05 0.03 0 0.09 0.026666667 3 2 0 5 1.666666667 0.370073522 -1.573704923 GO:0005737///cytoplasm+++GO:0030016///myofibril+++GO:0030018///Z disc GO:0051015///actin filament binding GO:0007015///actin filament organization+++GO:0014728///regulation of the force of skeletal muscle contraction+++GO:0016567///protein ubiquitination+++GO:0090076///relaxation of skeletal muscle 74493 74493 'Tnks2' mRNA 1128 1086 986 9.97 9.5 9.2 10.1 8.42 9.04 9.556666667 9.186666667 1341 1075 1175 1066.666667 1197 0.135667471 0.154413944 "GO:0000139///Golgi membrane+++GO:0000242///pericentriolar material+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm" "GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0000209///protein polyubiquitination+++GO:0000723///telomere maintenance+++GO:0006471///protein ADP-ribosylation+++GO:0016055///Wnt signaling pathway+++GO:0035264///multicellular organism growth+++GO:0040014///regulation of multicellular organism growth+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0070212///protein poly-ADP-ribosylation+++GO:0070213///protein auto-ADP-ribosylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904355///positive regulation of telomere capping+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening" 74498 74498 'Gorasp1' mRNA 1517.38 1657.82 1460.9 23.7 25.47 24.2 12.6 12.59 12.59 24.45666667 12.59333333 928.22 906.34 898.28 1545.366667 910.9466667 5.10E-22 -0.772788666 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0006487///protein N-linked glycosylation+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0061951///establishment of protein localization to plasma membrane 74499 74499 'Sost' mRNA 3 1 2 0.09 0.03 0.06 0.03 0.03 0.05 0.06 0.036666667 1 1 2 2 1.333333333 0.813136065 -0.59863572 "04310///Wnt signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action" GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008201///heparin binding+++GO:0036122///BMP binding "GO:0001503///ossification+++GO:0009612///response to mechanical stimulus+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030279///negative regulation of ossification+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0031333///negative regulation of protein complex assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0090090///negative regulation of canonical Wnt signaling pathway" 74504 74504 'Fam53a' mRNA 1253.78 1328.54 1253.16 33.91 35.66 35.91 31.82 27.34 26.38 35.16 28.51333333 1353.59 1142.06 1112.38 1278.493333 1202.676667 0.344345232 -0.101368564 GO:0005634///nucleus GO:0003674///molecular_function GO:0006606///protein import into nucleus 74511 74511 'Lrrc17' mRNA 6 9 6 0.15 0.23 0.16 0.09 0.18 0.14 0.18 0.136666667 4 8 6 7 6 0.863090843 -0.224254271 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix GO:0003674///molecular_function GO:0001503///ossification+++GO:0001649///osteoblast differentiation+++GO:0033687///osteoblast proliferation+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048539///bone marrow development 74513 74513 'Neto2' mRNA 76 73 80 0.67 0.63 0.75 0.5 0.45 0.46 0.683333333 0.47 64 55 56 76.33333333 58.33333333 0.228672144 -0.403080667 GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse GO:0035255///ionotropic glutamate receptor binding GO:2000312///regulation of kainate selective glutamate receptor activity+++GO:2000463///positive regulation of excitatory postsynaptic potential 74519 74519 'Cyp2j9' mRNA 830 848 872 24.42 24.1 26.62 12.12 11.69 12.9 25.04666667 12.23666667 470 455 498 850 474.3333333 1.74E-15 -0.854916755 00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04913///Ovarian steroidogenesis+++05417///Lipid and atherosclerosis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0008395///steroid hydroxylase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0071614///linoleic acid epoxygenase activity" GO:0006082///organic acid metabolic process+++GO:0006690///icosanoid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0043651///linoleic acid metabolic process 74521 74521 'Ppp4r4' mRNA 202 198 117 3.07 3 1.97 0.91 1.11 1.02 2.68 1.013333333 65 82 73 172.3333333 73.33333333 1.87E-06 -1.232275693 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0008287///protein serine/threonine phosphatase complex GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity GO:0001835///blastocyst hatching+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0080163///regulation of protein serine/threonine phosphatase activity 74522 74522 'Morc2a' mRNA 763 835 674 7.57 8.11 7.25 5.85 6.93 7.33 7.643333333 6.703333333 671 770 798 757.3333333 746.3333333 0.863090843 -0.028065891 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0006338///chromatin remodeling+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0090309///positive regulation of methylation-dependent chromatin silencing" 74525 74525 'Fam234b' mRNA 1824 1922 1923 23.32 24.13 26.05 14.47 13.06 12.3 24.5 13.27666667 1304 1151 1074 1889.666667 1176.333333 1.49E-15 -0.69822815 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 74528 74528 'Mgme1' mRNA 438 415 446 8.53 7.98 9.34 6.53 6.17 7.22 8.616666667 6.64 379 356 416 433 383.6666667 0.215682849 -0.188201832 GO:0005739///mitochondrion GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008297///single-stranded DNA exodeoxyribonuclease activity+++GO:0016787///hydrolase activity GO:0000002///mitochondrial genome maintenance+++GO:0006264///mitochondrial DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043504///mitochondrial DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 74533 74533 'Gzf1' mRNA 583 550 561 7.61 7.05 7.76 6.93 7.2 7.22 7.473333333 7.116666667 612 621 617 564.6666667 616.6666667 0.376102091 0.114995563 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 74549 74549 'Mau2' mRNA 3133.65 3156.46 3027.87 22.88 22.68 23.55 14.96 14.49 14.63 23.03666667 14.69333333 2354.13 2215.24 2237.94 3105.993333 2269.103333 1.10E-13 -0.465015775 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body+++GO:0032116///SMC loading complex+++GO:0090694///Scc2-Scc4 cohesin loading complex GO:0003690///double-stranded DNA binding+++GO:0047485///protein N-terminus binding GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007064///mitotic sister chromatid cohesion+++GO:0034088///maintenance of mitotic sister chromatid cohesion+++GO:0051301///cell division+++GO:0071921///cohesin loading 74551 74551 'Pck2' mRNA 678 625 592 11.49 10.41 11.07 10.07 10.01 9.64 10.99 9.906666667 680 645 630 631.6666667 651.6666667 0.821779532 0.033936251 00010///Glycolysis / Gluconeogenesis+++00020///Citrate cycle (TCA cycle)+++00620///Pyruvate metabolism+++03320///PPAR signaling pathway+++04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04964///Proximal tubule bicarbonate reclamation GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0004611///phosphoenolpyruvate carboxykinase activity+++GO:0004613///phosphoenolpyruvate carboxykinase (GTP) activity+++GO:0005525///GTP binding+++GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0017076///purine nucleotide binding+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0006090///pyruvate metabolic process+++GO:0006094///gluconeogenesis+++GO:0006107///oxaloacetate metabolic process+++GO:0006116///NADH oxidation+++GO:0019543///propionate catabolic process+++GO:0032024///positive regulation of insulin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0032869///cellular response to insulin stimulus+++GO:0033993///response to lipid+++GO:0042594///response to starvation+++GO:0046327///glycerol biosynthetic process from pyruvate+++GO:0070365///hepatocyte differentiation+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071548///response to dexamethasone+++GO:0071549///cellular response to dexamethasone stimulus 74552 74552 'Nipal3' mRNA 588.34 542.12 511.98 6.16 5.58 5.68 3.03 2.97 3.25 5.806666667 3.083333333 328.82 321 343.07 547.48 330.9633333 2.32E-09 -0.736651513 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015095///magnesium ion transmembrane transporter activity GO:0002377///immunoglobulin production+++GO:0007610///behavior+++GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 74556 74556 'Themis3' mRNA 24 25 19 0.52 0.54 0.44 0.09 0.1 0.06 0.5 0.083333333 5 5 3 22.66666667 4.333333333 0.001271417 -2.394509733 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0050852///T cell receptor signaling pathway 74558 74558 'Gvin1' mRNA 142.13 77.41 201.57 0.84 0.46 1.29 3.49 3.22 3.08 0.863333333 3.263333333 669.34 615.29 584.04 140.37 622.89 5.34E-07 2.121113323 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005525///GTP binding GO:0008150///biological_process 74559 74559 'Elovl7' mRNA 2076.11 2088.08 2033.25 20.56 20.23 21.3 16.39 15.38 17.15 20.69666667 16.30666667 1914 1763 1951.14 2065.813333 1876.046667 0.054007116 -0.151373332 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process" 74561 74561 'Nkx6-3' mRNA 0 2 3 0 0.05 0.08 0 0.02 0.16 0.043333333 0.06 0 1 7 1.666666667 2.666666667 0.804407527 0.652979735 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001709///cell fate determination+++GO:0002067///glandular epithelial cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 74562 74562 'Fer1l4' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0007009///plasma membrane organization 74563 74563 'Rasgef1c' mRNA 176 232 229 4.03 4.99 5.43 6.5 6.01 6.53 4.816666667 6.346666667 333 297 312 212.3333333 314 0.001685779 0.549526052 GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity 74568 74568 'Mlkl' mRNA 47 47 56 1.27 1.24 1.63 7.73 7.09 6.1 1.38 6.973333333 328 291 254 50 291 1.77E-31 2.525396534 04217///Necroptosis+++04668///TNF signaling pathway+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004706///JUN kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:0006468///protein phosphorylation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0012501///programmed cell death+++GO:0051607///defense response to virus+++GO:0070207///protein homotrimerization+++GO:0070266///necroptotic process+++GO:0097527///necroptotic signaling pathway+++GO:0097528///execution phase of necroptosis 74569 74569 'Ttc17' mRNA 1089 1042 848 14.73 13.38 11.75 12.69 10.99 13.05 13.28666667 12.24333333 1098 919 1076 993 1031 0.747966572 0.045343146 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0030041///actin filament polymerization+++GO:0044782///cilium organization 74570 74570 'Zkscan1' mRNA 743 683 611 4.76 4.29 4.14 4.28 3.76 4.16 4.396666667 4.066666667 771 662 724 679 719 0.596976282 0.072063315 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 74574 74574 'Lvrn' mRNA 8 4 2 0.12 0.06 0.03 0.61 0.37 0.48 0.07 0.486666667 45 29 36 4.666666667 36.66666667 6.21E-06 2.967230856 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0043171///peptide catabolic process 74577 74577 'Glb1l' mRNA 595.66 661.26 662.01 7.18 7.35 8.21 6.35 6.75 6.51 7.58 6.536666667 587.41 607.6 572.54 639.6433333 589.1833333 0.320814738 -0.132144485 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005773///vacuole "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004565///beta-galactosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process 74580 74580 'Pyroxd2' mRNA 125 128 111 2.2 2.21 2.07 3.49 4.82 3.25 2.16 3.853333333 229 309 207 121.3333333 248.3333333 1.12E-06 1.026060434 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0016491///oxidoreductase activity GO:0007005///mitochondrion organization 74585 74585 'Sppl3' mRNA 721 647 498 14.16 12.48 10.36 12.97 10.76 12.56 12.33333333 12.09666667 761 617 714 622 697.3333333 0.284698675 0.157366056 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane "GO:0004190///aspartic-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0042803///protein homodimerization activity" GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0032092///positive regulation of protein binding+++GO:0033619///membrane protein proteolysis+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0050852///T cell receptor signaling pathway+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade 74589 74589 'Kbtbd12' mRNA 0 4 2 0 0.11 0.06 0.02 0.19 0.12 0.056666667 0.11 2 8 5 2 5 0.434116475 1.324848346 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74591 74591 'Abca12' mRNA 0 0 1 0 0 0.01 0 0.01 0 0.003333333 0.003333333 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 02010///ABC transporters GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097209///epidermal lamellar body+++GO:0097234///epidermal lamellar body membrane "GO:0000166///nucleotide binding+++GO:0005102///signaling receptor binding+++GO:0005319///lipid transporter activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0003336///corneocyte desquamation+++GO:0006672///ceramide metabolic process+++GO:0006869///lipid transport+++GO:0006886///intracellular protein transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:0030216///keratinocyte differentiation+++GO:0031424///keratinization+++GO:0032379///positive regulation of intracellular lipid transport+++GO:0032940///secretion by cell+++GO:0033700///phospholipid efflux+++GO:0034204///lipid translocation+++GO:0035627///ceramide transport+++GO:0043129///surfactant homeostasis+++GO:0043589///skin morphogenesis+++GO:0045055///regulated exocytosis+++GO:0045616///regulation of keratinocyte differentiation+++GO:0048286///lung alveolus development+++GO:0055085///transmembrane transport+++GO:0055088///lipid homeostasis+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0061436///establishment of skin barrier+++GO:0072659///protein localization to plasma membrane+++GO:1902995///positive regulation of phospholipid efflux+++GO:1903064///positive regulation of reverse cholesterol transport+++GO:2000010///positive regulation of protein localization to cell surface 74596 74596 'Cds1' mRNA 750 763 729 10.81 10.8 11.01 7.05 6.36 7.06 10.87333333 6.823333333 569 496 547 747.3333333 537.3333333 4.11E-06 -0.488422709 00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0016779///nucleotidyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0140042///lipid droplet formation 74600 74600 'Mrpl47' mRNA 254 236 258 19.32 17.78 20.82 19.99 21.75 22.48 19.30666667 21.40666667 301 319 327 249.3333333 315.6666667 0.047463153 0.327441936 GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process+++GO:0032543///mitochondrial translation 74603 74603 'Cd200r3' mRNA 1 0 4 0.05 0 0.07 0.07 0.34 0.19 0.04 0.2 2 9 7 1.666666667 6 0.25975805 1.811152924 05167///Kaposi sarcoma-associated herpesvirus infection GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0038023///signaling receptor activity GO:0150077///regulation of neuroinflammatory response 74610 74610 'Abcb8' mRNA 1411.61 1620.55 1339.71 25.43 28.52 25.44 15.8 16.03 16.97 26.46333333 16.26666667 994.09 989.21 1034.2 1457.29 1005.833333 3.07E-10 -0.543632722 02010///ABC transporters GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport 74614 74614 'Ocstamp' mRNA 0 2 3 0 0.06 0.09 0.53 0.96 0.76 0.05 0.75 21 37 29 1.666666667 29 6.10E-06 4.107347998 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0030154///cell differentiation+++GO:0034241///positive regulation of macrophage fusion+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071391///cellular response to estrogen stimulus+++GO:0072674///multinuclear osteoclast differentiation+++GO:0090290///positive regulation of osteoclast proliferation 74616 74616 'Scrn3' mRNA 489 579 577 9.97 11.94 12.99 8.2 8.25 9.29 11.63333333 8.58 416 402 444 548.3333333 420.6666667 0.003323711 -0.396154061 GO:0003674///molecular_function+++GO:0016805///dipeptidase activity+++GO:0070004///cysteine-type exopeptidase activity GO:0006508///proteolysis 74617 74617 'Scpep1' mRNA 1896 1952 2155 51.85 52.58 62.51 112.33 113.16 112.04 55.64666667 112.51 4723 4645 4560 2001 4642.666667 1.58E-53 1.19886013 GO:0005576///extracellular region+++GO:0005829///cytosol GO:0004180///carboxypeptidase activity+++GO:0004185///serine-type carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0042573///retinoic acid metabolic process+++GO:0045776///negative regulation of blood pressure+++GO:0097746///regulation of blood vessel diameter 74626 74626 'Tmem81' mRNA 21.63 8.46 30.07 0.72 0.28 1.1 0.93 0.66 1.38 0.7 0.99 30.87 22.19 44.22 20.05333333 32.42666667 0.304108977 0.670940833 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 74637 74637 'Shpk' mRNA 401 449 475 7.96 8.78 10.01 5.56 6.22 4.92 8.916666667 5.566666667 322 352 276 441.6666667 316.6666667 0.001493155 -0.494300782 GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0050277///sedoheptulokinase activity" "GO:0005975///carbohydrate metabolic process+++GO:0009052///pentose-phosphate shunt, non-oxidative branch+++GO:0016310///phosphorylation+++GO:0035963///cellular response to interleukin-13+++GO:0043030///regulation of macrophage activation+++GO:0050727///regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071353///cellular response to interleukin-4" 74644 74644 '4930426D05Rik' mRNA 100.6 102 105 3.81 3.67 4.11 0.73 0.42 0.85 3.863333333 0.666666667 22 12 25 102.5333333 19.66666667 1.20E-11 -2.394990483 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74645 74645 'Tent5c' mRNA 507 472 463 5.94 5.81 5.21 6.96 7.16 7.34 5.653333333 7.153333333 637 672 661 480.6666667 656.6666667 1.11E-04 0.439321175 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:1990817///RNA adenylyltransferase activity GO:0001701///in utero embryonic development+++GO:0048255///mRNA stabilization 74646 74646 'Spsb1' mRNA 1126 1179 1021 20.17 20.76 19.38 16.72 14.72 14.03 20.10333333 15.15666667 1073 921 873 1108.666667 955.6666667 0.025455353 -0.225382913 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex "GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 74648 74648 'S100pbp' mRNA 487 491 428 6.19 6.03 5.74 5.79 5.72 6.17 5.986666667 5.893333333 524 502 544 468.6666667 523.3333333 0.261148742 0.149445346 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0048306///calcium-dependent protein binding GO:0008150///biological_process 74653 74653 'Pomk' mRNA 825 912 914 12.44 13.53 14.62 10.53 11.06 10.06 13.53 10.55 804 825 744 883.6666667 791 0.133624624 -0.173059508 00515///Mannose type O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019200///carbohydrate kinase activity" GO:0001764///neuron migration+++GO:0006468///protein phosphorylation+++GO:0006493///protein O-linked glycosylation+++GO:0007420///brain development+++GO:0007611///learning or memory+++GO:0016310///phosphorylation+++GO:0019233///sensory perception of pain+++GO:0046835///carbohydrate phosphorylation+++GO:0050905///neuromuscular process 74665 74665 'Drc3' mRNA 2047 1976 1955 62.53 59.5 63.49 7.62 7.05 7.64 61.84 7.436666667 288 259 278 1992.666667 275 1.60E-210 -2.869814439 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0005515///protein binding GO:0008150///biological_process 74666 74666 '4930432K21Rik' mRNA 35 47 54 0.72 0.91 1.1 0.75 0.46 0.54 0.91 0.583333333 39 26 30 45.33333333 31.66666667 0.24692913 -0.538494749 GO:0005694///chromosome GO:0005515///protein binding GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0007283///spermatogenesis+++GO:0051321///meiotic cell cycle+++GO:1990918///double-strand break repair involved in meiotic recombination 74670 74670 'Zfp943' mRNA 543 482 487 10.98 9.6 10.45 6.59 5.76 5.88 10.34333333 6.076666667 375 320 324 504 339.6666667 9.24E-06 -0.582274487 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 74673 74673 'Spdye4a' mRNA 2 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation GO:0005575///cellular_component+++GO:0005634///nucleus GO:0019901///protein kinase binding GO:0007049///cell cycle+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity 74682 74682 'Wdr35' mRNA 1303 1328 1410 15.99 16.05 18.37 8.69 7.9 8.03 16.80333333 8.206666667 812 721 728 1347 753.6666667 3.67E-19 -0.852943327 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030991///intraciliary transport particle A+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0009636///response to toxic substance+++GO:0010629///negative regulation of gene expression+++GO:0030030///cell projection organization+++GO:0032496///response to lipopolysaccharide+++GO:0035721///intraciliary retrograde transport+++GO:0042073///intraciliary transport+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045907///positive regulation of vasoconstriction+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0097421///liver regeneration+++GO:1901555///response to paclitaxel+++GO:1905705///cellular response to paclitaxel+++GO:1990830///cellular response to leukemia inhibitory factor 74685 74685 'Lrrc74b' mRNA 361.14 291.63 247.7 8.7 6.87 6.34 0.86 0.77 0.92 7.303333333 0.85 44.19 37.39 39.35 300.1566667 40.31 1.85E-37 -2.913270166 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74691 74691 'Tdrd9' mRNA 40 23 32 0.5 0.28 0.47 0.11 0.04 0.17 0.416666667 0.106666667 9 3 14 31.66666667 8.666666667 0.003429956 -1.886842419 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0071547///piP-body GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0010529///negative regulation of transposition+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle 74694 74694 'Tbc1d30' mRNA 354 383 271 3.05 3.31 2.54 0.98 0.97 0.96 2.966666667 0.97 130 120 127 336 125.6666667 3.69E-16 -1.424928343 GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0036064///ciliary basal body GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity+++GO:1902018///negative regulation of cilium assembly 74711 74711 'Ttll9' mRNA 168 183 122 4.67 4.44 3.43 0.68 0.77 0.84 4.18 0.763333333 29 32 33 157.6666667 31.33333333 8.96E-17 -2.334897758 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015631///tubulin binding+++GO:0016874///ligase activity+++GO:0070740///tubulin-glutamic acid ligase activity GO:0000226///microtubule cytoskeleton organization+++GO:0006464///cellular protein modification process+++GO:0018095///protein polyglutamylation+++GO:0030317///flagellated sperm motility 74716 74716 'Wbp2nl' mRNA 5 7 11 0.23 0.32 0.53 0.04 0.08 0.08 0.36 0.066666667 1 2 2 7.666666667 1.666666667 0.090246605 -2.224426296 GO:0005634///nucleus+++GO:0033011///perinuclear theca+++GO:0036126///sperm flagellum+++GO:0061827///sperm head GO:0003713///transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0050699///WW domain binding "GO:0007343///egg activation+++GO:0035038///female pronucleus assembly+++GO:0035039///male pronucleus assembly+++GO:0045893///positive regulation of transcription, DNA-templated" 74717 74717 'Spata17' mRNA 363 433 412.2 15.62 18.52 18.83 0.7 2.03 1 17.65666667 1.243333333 28 57.3 31 402.7333333 38.76666667 1.24E-48 -3.390123974 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005516///calmodulin binding GO:0008150///biological_process 74718 74718 'Snx16' mRNA 536 519 568 11.29 11.13 12.58 11.46 11.19 11.59 11.66666667 11.41333333 625 594 599 541 606 0.259418169 0.149245735 GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding GO:0006622///protein targeting to lysosome+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0045022///early endosome to late endosome transport 74729 74729 'Setmar' mRNA 147 139 181 5.31 4.95 6.94 3.68 3.06 3.09 5.733333333 3.276666667 118 95 95 155.6666667 102.6666667 0.011441431 -0.620324317 00310///Lysine degradation GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0035861///site of double-strand break GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004519///endonuclease activity+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0042803///protein homodimerization activity+++GO:0044547///DNA topoisomerase binding+++GO:0046872///metal ion binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific) "GO:0000729///DNA double-strand break processing+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006325///chromatin organization+++GO:0008283///cell proliferation+++GO:0010452///histone H3-K36 methylation+++GO:0015074///DNA integration+++GO:0031297///replication fork processing+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0044774///mitotic DNA integrity checkpoint+++GO:0051568///histone H3-K4 methylation+++GO:0051726///regulation of cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0097676///histone H3-K36 dimethylation+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:2001251///negative regulation of chromosome organization" 74732 74732 'Stx11' mRNA 64 56 69 1.24 1.11 1.43 5.98 5.35 5.76 1.26 5.696666667 325 291 304 63 306.6666667 1.90E-30 2.268332844 04130///SNARE interactions in vesicular transport GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0045335///phagocytic vesicle+++GO:0048787///presynaptic active zone membrane GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity GO:0001913///T cell mediated cytotoxicity+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006906///vesicle fusion+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043312///neutrophil degranulation+++GO:0043316///cytotoxic T cell degranulation+++GO:0043320///natural killer cell degranulation+++GO:0048278///vesicle docking+++GO:0061025///membrane fusion+++GO:0071346///cellular response to interferon-gamma 74734 74734 'Rhoh' mRNA 33.32 22 31 0.36 0.21 0.36 2.49 2.51 2.05 0.31 2.35 267 262 217.45 28.77333333 248.8166667 3.38E-34 3.102769816 04670///Leukocyte transendothelial migration+++05132///Salmonella infection GO:0001772///immunological synapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019210///kinase inhibitor activity+++GO:0019901///protein kinase binding GO:0007015///actin filament organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008045///motor neuron axon guidance+++GO:0008360///regulation of cell shape+++GO:0016601///Rac protein signal transduction+++GO:0030031///cell projection assembly+++GO:0030217///T cell differentiation+++GO:0030865///cortical cytoskeleton organization+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0043086///negative regulation of catalytic activity+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043652///engulfment of apoptotic cell+++GO:0045576///mast cell activation+++GO:0045582///positive regulation of T cell differentiation+++GO:1902622///regulation of neutrophil migration 74735 74735 'Trim14' mRNA 144.31 121.35 92.68 2.94 3.05 2.42 12.66 13.62 15.62 2.803333333 13.96666667 445.4 623 628.16 119.4466667 565.52 3.25E-34 2.245348316 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0002376///immune system process+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0032897///negative regulation of viral transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity" 74737 74737 'Pcf11' mRNA 490 474 463 4.28 4.03 4.29 3.65 3.18 3.71 4.2 3.513333333 484 400 468 475.6666667 450.6666667 0.56368142 -0.09079944 03015///mRNA surveillance pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005849///mRNA cleavage factor complex GO:0000993///RNA polymerase II complex binding+++GO:0003729///mRNA binding GO:0006369///termination of RNA polymerase II transcription+++GO:0006378///mRNA polyadenylation+++GO:0006379///mRNA cleavage 74741 74741 'C2cd5' mRNA 1278.74 1260.12 1312.99 13.1 12.67 14.47 7.9 6.9 7.02 13.41333333 7.273333333 876.08 736.98 742.03 1283.95 785.03 5.69E-14 -0.724698503 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032587///ruffle membrane+++GO:0034451///centriolar satellite+++GO:0042995///cell projection GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008289///lipid binding+++GO:0046872///metal ion binding GO:0006906///vesicle fusion+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0015031///protein transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0046326///positive regulation of glucose import+++GO:0065002///intracellular protein transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0090314///positive regulation of protein targeting to membrane 74747 74747 'Ddit4' mRNA 694 754 476 23.94 25.64 17.42 23.26 22.11 22.46 22.33333333 22.61 775 719 724 641.3333333 739.3333333 0.170127992 0.201399854 04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++05206///MicroRNAs in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0071889///14-3-3 protein binding GO:0001666///response to hypoxia+++GO:0001764///neuron migration+++GO:0006915///apoptotic process+++GO:0007420///brain development+++GO:0009968///negative regulation of signal transduction+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0030182///neuron differentiation+++GO:0032006///regulation of TOR signaling+++GO:0032007///negative regulation of TOR signaling+++GO:0032984///protein-containing complex disassembly+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0045820///negative regulation of glycolytic process+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0051607///defense response to virus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0072593///reactive oxygen species metabolic process+++GO:1901216///positive regulation of neuron death+++GO:1902532///negative regulation of intracellular signal transduction 74748 74748 'Slamf8' mRNA 9.03 29 9 0.27 0.8 0.27 4.17 4.24 4.62 0.446666667 4.343333333 170.2 167.53 181.95 15.67666667 173.2266667 3.78E-23 3.460373946 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0002336///B-1 B cell lineage commitment+++GO:0010760///negative regulation of macrophage chemotaxis+++GO:0033860///regulation of NAD(P)H oxidase activity+++GO:0035690///cellular response to drug+++GO:0042742///defense response to bacterium+++GO:0043549///regulation of kinase activity+++GO:0045577///regulation of B cell differentiation+++GO:0060266///negative regulation of respiratory burst involved in inflammatory response+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0090383///phagosome acidification+++GO:1902623///negative regulation of neutrophil migration+++GO:2000509///negative regulation of dendritic cell chemotaxis 74753 74753 'Trmo' mRNA 150 220 212 5.01 7.22 7.82 3.88 4.97 5.06 6.683333333 4.636666667 124 146 158 194 142.6666667 0.054423951 -0.456317404 GO:0005575///cellular_component GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0016430///tRNA (adenine-N6-)-methyltransferase activity+++GO:0016740///transferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 74754 74754 'Dhcr24' mRNA 451 433 338 6.04 5.71 4.8 3.24 2.93 3.45 5.516666667 3.206666667 278 246 287 407.3333333 270.3333333 6.27E-05 -0.598995852 00100///Steroid biosynthesis GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000246///delta24(24-1) sterol reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0019899///enzyme binding+++GO:0042605///peptide antigen binding+++GO:0050614///delta24-sterol reductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006979///response to oxidative stress+++GO:0007265///Ras protein signal transduction+++GO:0008104///protein localization+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0009725///response to hormone+++GO:0009888///tissue development+++GO:0016125///sterol metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0030539///male genitalia development+++GO:0031639///plasminogen activation+++GO:0033489///cholesterol biosynthetic process via desmosterol+++GO:0042987///amyloid precursor protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043588///skin development+++GO:0061024///membrane organization 74760 74760 'Rab3il1' mRNA 911 859 845 21.75 20.25 21.07 92.64 104.38 94 21.02333333 97.00666667 4536 4959 4483 871.6666667 4659.333333 1.84E-227 2.40767055 GO:0070319///Golgi to plasma membrane transport vesicle GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019900///kinase binding+++GO:0042802///identical protein binding GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0050790///regulation of catalytic activity 74761 74761 'Mxra8' mRNA 1955 1966 2058 48.67 48.21 54.36 91.49 94.77 90.41 50.41333333 92.22333333 4224 4273 4043 1993 4180 1.89E-50 1.055030047 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0060170///ciliary membrane GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0008150///biological_process+++GO:0060857///establishment of glial blood-brain barrier 74762 74762 'Mdga1' mRNA 207 261 193 1.35 1.7 1.37 1.51 1.55 1.54 1.473333333 1.533333333 273 275 264 220.3333333 270.6666667 0.11323287 0.289109972 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane+++GO:0098982///GABA-ergic synapse GO:0003674///molecular_function GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0030154///cell differentiation+++GO:0051964///negative regulation of synapse assembly+++GO:0099179///regulation of synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 74763 74763 'Naa60' mRNA 1908 1853 1879 45.39 43.46 47.44 46.83 43.8 46.57 45.43 45.73333333 2280 2076 2192 1880 2182.666667 0.008091255 0.202076305 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane "GO:0004402///histone acetyltransferase activity+++GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042803///protein homodimerization activity" GO:0006325///chromatin organization+++GO:0006334///nucleosome assembly+++GO:0006474///N-terminal protein amino acid acetylation+++GO:0007059///chromosome segregation+++GO:0008283///cell proliferation+++GO:0017196///N-terminal peptidyl-methionine acetylation+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation 74764 74764 'Klc4' mRNA 1146 1147 1120 26.53 26.11 27.33 24.58 25.06 23.71 26.65666667 24.45 1223 1228 1141 1137.666667 1197.333333 0.566592541 0.061821306 05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05132///Salmonella infection GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule GO:0003674///molecular_function GO:0008150///biological_process 74766 74766 'Yipf2' mRNA 1925.23 2048.17 1883.69 52.87 55.35 55.36 40.1 39.87 38.99 54.52666667 39.65333333 1650.75 1615.66 1567.85 1952.363333 1611.42 7.80E-05 -0.288554222 GO:0000138///Golgi trans cisterna+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005802///trans-Golgi network+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031902///late endosome membrane GO:0031267///small GTPase binding GO:0008150///biological_process+++GO:0016192///vesicle-mediated transport 74769 74769 'Pik3cb' mRNA 187 143 102 2.07 1.55 1.2 2.63 1.69 2.58 1.606666667 2.3 268 172 259 144 233 0.004463922 0.687440384 "00562///Inositol phosphate metabolism+++01521///EGFR tyrosine kinase inhibitor resistance+++01522///Endocrine resistance+++01524///Platinum drug resistance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++04066///HIF-1 signaling pathway+++04068///FoxO signaling pathway+++04070///Phosphatidylinositol signaling system+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04210///Apoptosis+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04360///Axon guidance+++04361///Axon regeneration+++04370///VEGF signaling pathway+++04380///Osteoclast differentiation+++04510///Focal adhesion+++04550///Signaling pathways regulating pluripotency of stem cells+++04611///Platelet activation+++04613///Neutrophil extracellular trap formation+++04620///Toll-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04668///TNF signaling pathway+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++04725///Cholinergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04910///Insulin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++04919///Thyroid hormone signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04926///Relaxin signaling pathway+++04929///GnRH secretion+++04930///Type II diabetes mellitus+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease+++04933///AGE-RAGE signaling pathway in diabetic complications+++04935///Growth hormone synthesis, secretion and action+++04960///Aldosterone-regulated sodium reabsorption+++04973///Carbohydrate digestion and absorption+++05010///Alzheimer disease+++05017///Spinocerebellar ataxia+++05020///Prion disease+++05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection+++05142///Chagas disease+++05146///Amoebiasis+++05160///Hepatitis C+++05161///Hepatitis B+++05162///Measles+++05163///Human cytomegalovirus infection+++05164///Influenza A+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05168///Herpes simplex virus 1 infection+++05169///Epstein-Barr virus infection+++05170///Human immunodeficiency virus 1 infection+++05171///Coronavirus disease - COVID-19+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05210///Colorectal cancer+++05211///Renal cell carcinoma+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05214///Glioma+++05215///Prostate cancer+++05218///Melanoma+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05222///Small cell lung cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer+++05230///Central carbon metabolism in cancer+++05231///Choline metabolism in cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer+++05415///Diabetic cardiomyopathy+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis" GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0031526///brush border membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016740///transferase activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0043560///insulin receptor substrate binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0052742///phosphatidylinositol kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity" GO:0001935///endothelial cell proliferation+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002931///response to ischemia+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006874///cellular calcium ion homeostasis+++GO:0006897///endocytosis+++GO:0006914///autophagy+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009611///response to wounding+++GO:0010595///positive regulation of endothelial cell migration+++GO:0010628///positive regulation of gene expression+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation+++GO:0016477///cell migration+++GO:0030168///platelet activation+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0040016///embryonic cleavage+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0060055///angiogenesis involved in wound healing+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1903671///negative regulation of sprouting angiogenesis 74770 74770 'Hhatl' mRNA 18096 18160 17699 531 524.29 552.75 220.65 218.98 217.2 536.0133333 218.9433333 8506 8275 8143 17985 8308 5.89E-115 -1.126556409 04340///Hedgehog signaling pathway GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0005515///protein binding+++GO:0016746///transferase activity, transferring acyl groups" GO:0060262///negative regulation of N-terminal protein palmitoylation 74772 74772 'Atp13a2' mRNA 2070.1 2105 1109.87 28.52 28.63 16.28 17.99 27.79 27.07 24.47666667 24.28333333 1496.95 2259 2177.02 1761.656667 1977.656667 0.703304273 0.173728554 GO:0000421///autophagosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005771///multivesicular body+++GO:0005776///autophagosome+++GO:0012506///vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0032585///multivesicular body membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:1905103///integral component of lysosomal membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0015417///polyamine-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0046872///metal ion binding+++GO:0070300///phosphatidic acid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0006812///cation transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0006879///cellular iron ion homeostasis+++GO:0006882///cellular zinc ion homeostasis+++GO:0006914///autophagy+++GO:0007041///lysosomal transport+++GO:0010628///positive regulation of gene expression+++GO:0010821///regulation of mitochondrion organization+++GO:0016241///regulation of macroautophagy+++GO:0016243///regulation of autophagosome size+++GO:0033157///regulation of intracellular protein transport+++GO:0034220///ion transmembrane transport+++GO:0034599///cellular response to oxidative stress+++GO:0050714///positive regulation of protein secretion+++GO:0052548///regulation of endopeptidase activity+++GO:0055069///zinc ion homeostasis+++GO:0055088///lipid homeostasis+++GO:0061462///protein localization to lysosome+++GO:0061909///autophagosome-lysosome fusion+++GO:0071287///cellular response to manganese ion+++GO:0097734///extracellular exosome biogenesis+++GO:0098655///cation transmembrane transport+++GO:1900180///regulation of protein localization to nucleus+++GO:1902047///polyamine transmembrane transport+++GO:1903543///positive regulation of exosomal secretion+++GO:1903710///spermine transmembrane transport+++GO:1905037///autophagosome organization+++GO:1905123///regulation of glucosylceramidase activity+++GO:1905165///regulation of lysosomal protein catabolic process+++GO:1990938///peptidyl-aspartic acid autophosphorylation+++GO:2000152///regulation of ubiquitin-specific protease activity 74775 74775 'Lmbr1l' mRNA 300 234 233 7.73 5.99 6.44 6.21 6.3 6.98 6.72 6.496666667 274 272 302 255.6666667 282.6666667 0.506973079 0.134823065 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0007165///signal transduction+++GO:0016055///Wnt signaling pathway+++GO:0030217///T cell differentiation+++GO:0042098///T cell proliferation+++GO:0060218///hematopoietic stem cell differentiation+++GO:0070231///T cell apoptotic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway 74776 74776 'Ppa2' mRNA 1295 1261 1137 57.1 55.02 53.41 48.14 48.5 49.77 55.17666667 48.80333333 1246 1216 1251 1231 1237.666667 0.990547257 -0.002254361 00190///Oxidative phosphorylation GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000287///magnesium ion binding+++GO:0004427///inorganic diphosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0006796///phosphate-containing compound metabolic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0071344///diphosphate metabolic process 74777 74777 'Selenon' mRNA 381 380 295 6.02 5.91 4.94 9.09 9.4 9.53 5.623333333 9.34 662 669 672 352 667.6666667 2.02E-14 0.916345357 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity GO:0003016///respiratory system process+++GO:0007005///mitochondrion organization+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0014858///positive regulation of skeletal muscle cell proliferation+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0033555///multicellular organismal response to stress+++GO:0034599///cellular response to oxidative stress+++GO:0043403///skeletal muscle tissue regeneration+++GO:0048286///lung alveolus development+++GO:0048741///skeletal muscle fiber development+++GO:0055074///calcium ion homeostasis+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0071313///cellular response to caffeine+++GO:1902884///positive regulation of response to oxidative stress 74778 74778 'Rrp7a' mRNA 1298.39 1284.74 1326.18 38.22 37.3 41.51 43.82 41.21 39.59 39.01 41.54 1716.81 1572.96 1500 1303.103333 1596.59 0.001416819 0.278973406 03008///Ribosome biogenesis in eukaryotes GO:0005737///cytoplasm+++GO:0032545///CURI complex+++GO:0034456///UTP-C complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0000028///ribosomal small subunit assembly+++GO:0001825///blastocyst formation+++GO:0006364///rRNA processing 74781 74781 'Wipi2' mRNA 2429 2624 2529 32.45 34.4 35.67 27.13 25.78 24.79 34.17333333 25.9 2338 2181 2073 2527.333333 2197.333333 0.005191204 -0.214951063 04136///Autophagy - other+++04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis GO:0000407///phagophore assembly site+++GO:0005654///nucleoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0032991///protein-containing complex+++GO:0034045///phagophore assembly site membrane "GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0010314///phosphatidylinositol-5-phosphate binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0009267///cellular response to starvation+++GO:0034497///protein localization to phagophore assembly site+++GO:0044804///autophagy of nucleus+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0098792///xenophagy 74782 74782 'Glt8d2' mRNA 23.11 17.11 21.36 0.61 0.44 0.57 1.13 1.68 0.96 0.54 1.256666667 50.46 71.74 40.89 20.52666667 54.36333333 0.001833554 1.389207626 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" 74838 74838 'Naa15' mRNA 744 812 703 6.48 6.95 6.49 7.42 8.28 8.49 6.64 8.063333333 981 1070 1087 753 1046 2.16E-06 0.465162133 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0031415///NatA complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0043022///ribosome binding "GO:0001525///angiogenesis+++GO:0006474///N-terminal protein amino acid acetylation+++GO:0007275///multicellular organism development+++GO:0017196///N-terminal peptidyl-methionine acetylation+++GO:0030154///cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050821///protein stabilization" 74840 74840 'Manf' mRNA 1856 1756 1755 142.02 133.06 142.5 217.46 220.49 216.91 139.1933333 218.2866667 3255 3215 3136 1789 3202 9.96E-36 0.827786805 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016529///sarcoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0048471///perinuclear region of cytoplasm GO:0003674///molecular_function+++GO:0008083///growth factor activity+++GO:0008289///lipid binding+++GO:0120146///sulfatide binding GO:0002014///vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure+++GO:0006986///response to unfolded protein+++GO:0007165///signal transduction+++GO:0031175///neuron projection development+++GO:0071542///dopaminergic neuron differentiation+++GO:1905897///regulation of response to endoplasmic reticulum stress 74841 74841 'Usp38' mRNA 592 661 700 6.8 7.48 8.51 5.67 5.55 5.96 7.596666667 5.726666667 571 542 572 651 561.6666667 0.079013362 -0.227947638 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 74843 74843 'Mss51' mRNA 39 35 37 1.23 1.33 1.34 0.59 0.56 0.53 1.3 0.56 21 16 18 37 18.33333333 0.036059547 -1.02754767 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 74855 74855 'Fam228a' mRNA 6.05 7.17 11.21 0.11 0.11 0.2 0.12 0.02 0.03 0.14 0.056666667 7 1.06 2.13 8.143333333 3.396666667 0.300836495 -1.300568953 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74868 74868 'Tmem65' mRNA 382 383 324 6.27 6.13 5.78 8.07 7.36 7.73 6.06 7.72 569 503.93 528 363 533.6433333 1.03E-05 0.54509572 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0003231///cardiac ventricle development+++GO:1903779///regulation of cardiac conduction 74890 74890 'Morn3' mRNA 13 10 10 0.66 0.58 0.62 0.11 0.23 0.37 0.62 0.236666667 2 4 7 11 4.333333333 0.182479359 -1.349767543 GO:0003674///molecular_function GO:0008150///biological_process 74892 74892 '4930447A16Rik' mRNA 0 0 1 0 0 0.14 0 0 0 0.046666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74895 74895 'Ccdc181' mRNA 589 672 554 17.85 20.16 17.83 7.95 7.39 9.27 18.61333333 8.203333333 302 274 340 605 305.3333333 1.28E-14 -0.996034433 GO:0002177///manchette+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0008017///microtubule binding GO:0008150///biological_process 74901 74901 'Kbtbd11' mRNA 142 145 124 1.04 1.06 0.96 1.13 0.97 1.35 1.02 1.15 177 145 200 137 174 0.1442375 0.334638723 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74918 74918 'Iqca' mRNA 432 372 403 7.21 6.11 7.13 0.55 0.49 0.6 6.816666667 0.546666667 38 33 40 402.3333333 37 1.58E-61 -3.456372992 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding+++GO:0016887///ATPase activity GO:0008150///biological_process 74919 74919 'Slc35f6' mRNA 969 1007 977 17.15 17.5 18.37 27.94 29.46 28.25 17.67333333 28.55 1817 1870 1775 984.3333333 1820.666667 2.26E-28 0.87554232 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0008284///positive regulation of cell proliferation+++GO:0055085///transmembrane transport+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 74934 74934 'Armc4' mRNA 1883 1825 1811 30.11 28.39 30.13 2.1 2.24 2.05 29.54333333 2.13 151 159 147 1839.666667 152.3333333 8.34E-251 -3.606213059 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0003356///regulation of cilium beat frequency+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0021591///ventricular system development+++GO:0030030///cell projection organization+++GO:0036158///outer dynein arm assembly 74954 74954 '4930503E14Rik' mRNA 1 0 0 0.05 0 0 0 0 0 0.016666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 74978 74978 'Lrriq1' mRNA 939 948 869 14.21 13.97 13.88 1.34 1.19 1.69 14.02 1.406666667 96 86 112 918.6666667 98 3.04E-125 -3.239585549 GO:0005737///cytoplasm GO:0019901///protein kinase binding GO:0008150///biological_process 74987 74987 'Cldn34d' mRNA 1 0 0 0.06 0 0 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0005198///structural molecule activity GO:0007155///cell adhesion+++GO:0070830///bicellular tight junction assembly 74996 74996 'Usp47' mRNA 2147 2263 2135 20.41 21.27 21.59 16.78 16.31 16.32 21.09 16.47 2020 1932 1905 2181.666667 1952.333333 0.018523771 -0.172201734 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0071987///WD40-repeat domain binding+++GO:0101005///ubiquitinyl hydrolase activity "GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009410///response to xenobiotic stimulus+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0016579///protein deubiquitination+++GO:0030307///positive regulation of cell growth+++GO:0031647///regulation of protein stability+++GO:0034644///cellular response to UV+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0042493///response to drug+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage" 74998 74998 'Rab11fip2' mRNA 307 340 301 2.56 2.76 2.7 1.88 1.24 1.76 2.673333333 1.626666667 266 175 237 316 226 0.005516241 -0.497140324 04144///Endocytosis GO:0001891///phagocytic cup+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane GO:0019901///protein kinase binding+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0006909///phagocytosis+++GO:0015031///protein transport+++GO:0030010///establishment of cell polarity+++GO:0035669///TRAM-dependent toll-like receptor 4 signaling pathway+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0043547///positive regulation of GTPase activity+++GO:0045055///regulated exocytosis+++GO:1903078///positive regulation of protein localization to plasma membrane 75007 75007 'Mindy1' mRNA 1609.57 1752.39 1683.42 32.07 34.6 36.06 29.11 30.26 30.15 34.24333333 29.84 1660.05 1680.05 1648.02 1681.793333 1662.706667 0.797440972 -0.028212109 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0071944///cell periphery GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016807///cysteine-type carboxypeptidase activity+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0071108///protein K48-linked deubiquitination 75011 75011 '4930488N24Rik' mRNA 3.19 1 2 0.07 0.02 0.05 0.06 0.02 0 0.046666667 0.026666667 3 1 0 2.063333333 1.333333333 0.820747739 -0.613441429 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75013 75013 'Ct55' mRNA 1 0 0 0.05 0 0 0 0.28 0 0.016666667 0.093333333 0 7 0 0.333333333 2.333333333 0.39592735 2.715535153 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75015 75015 '4930503B20Rik' mRNA 50 33 45 1.73 1.11 1.6 0.65 0.35 0.51 1.48 0.503333333 21 12 20 42.66666667 17.66666667 0.008210825 -1.29054299 GO:0005634///nucleus+++GO:0005739///mitochondrion GO:0003682///chromatin binding+++GO:0042393///histone binding "GO:0045892///negative regulation of transcription, DNA-templated" 75019 75019 'Rnase10' mRNA 0 4 4 0 0.15 0.17 0.2 0.14 0.28 0.106666667 0.206666667 6 4 8 2.666666667 6 0.44721965 1.146276469 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0004540///ribonuclease activity GO:0003382///epithelial cell morphogenesis+++GO:0007155///cell adhesion+++GO:0007338///single fertilization+++GO:0008584///male gonad development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0034113///heterotypic cell-cell adhesion+++GO:0072520///seminiferous tubule development+++GO:0080154///regulation of fertilization+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:1902093///positive regulation of flagellated sperm motility 75029 75029 'Purg' mRNA 101 100 94 3.07 2.92 2.94 2.11 1.52 2.2 2.976666667 1.943333333 90 58 82 98.33333333 76.66666667 0.224723646 -0.372950005 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0032422///purine-rich negative regulatory element binding" GO:0006357///regulation of transcription by RNA polymerase II 75033 75033 'Mei4' mRNA 6 6 15 0.08 0.08 0.18 0.07 0.08 0.04 0.113333333 0.063333333 5 6 3.9 9 4.966666667 0.386756891 -0.980929464 GO:0000800///lateral element+++GO:0005694///chromosome GO:0005515///protein binding GO:0006310///DNA recombination+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0042138///meiotic DNA double-strand break formation+++GO:0048477///oogenesis+++GO:0051321///meiotic cell cycle 75040 75040 'Efcab10' mRNA 270 248 265 29.47 26.81 30.69 1.69 2.75 3.05 28.99 2.496666667 18 28 30 261 25.33333333 2.03E-39 -3.376564343 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0008150///biological_process 75050 75050 'Kif27' mRNA 695.92 692.43 467.83 5.16 5.12 3.81 0.53 0.55 0.38 4.696666667 0.486666667 78.96 82.39 51.75 618.7266667 71.03333333 1.95E-61 -3.139114281 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005929///cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:1990939///ATP-dependent microtubule motor activity GO:0003351///epithelial cilium movement+++GO:0007018///microtubule-based movement+++GO:0021591///ventricular system development+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly 75051 75051 'Ccdc173' mRNA 178 175 205 5.67 5.33 7.02 2.54 2.26 3.03 6.006666667 2.61 90 80 108 186 92.66666667 6.58E-06 -1.021413369 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75062 75062 'Sf3a3' mRNA 1126 1190 1148 36.9 38.63 40.49 37.46 40.19 37.12 38.67333333 38.25666667 1302 1358 1240 1154.666667 1300 0.092410024 0.159268982 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:1903241///U2-type prespliceosome assembly" 75064 75064 'Zcchc13' mRNA 1 2 2 0.06 0.12 0.12 0 0 0 0.1 0 0 0 0 1.666666667 0 0.324592415 -3.197419472 GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003727///single-stranded RNA binding+++GO:0003729///mRNA binding+++GO:0008270///zinc ion binding+++GO:0045182///translation regulator activity GO:2000767///positive regulation of cytoplasmic translation 75079 75079 'Zbtb49' mRNA 318 347 341 5.99 6.86 6.57 3.78 3.7 4.49 6.473333333 3.99 246 201 257 335.3333333 234.6666667 0.001145276 -0.528851338 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle 75083 75083 'Usp50' mRNA 0 1 2 0 0.03 0.07 0.03 0 0.06 0.033333333 0.03 1 0 2 1 1 0.996322951 -0.0447227 GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0019897///extrinsic component of plasma membrane+++GO:0030496///midbody+++GO:0031313///extrinsic component of endosome membrane+++GO:0043197///dendritic spine GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0019783///ubiquitin-like protein-specific protease activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007032///endosome organization+++GO:0007265///Ras protein signal transduction+++GO:0016579///protein deubiquitination+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032741///positive regulation of interleukin-18 production+++GO:0035063///nuclear speck organization+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:2001056///positive regulation of cysteine-type endopeptidase activity 75087 75087 '4930505A04Rik' mRNA 13 6 6 0.92 0.42 0.45 0.06 0.06 0.19 0.596666667 0.103333333 1 1 3 8.333333333 1.666666667 0.073386381 -2.325914553 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75089 75089 'Uhrf1bp1l' mRNA 1174.79 1106.28 1143.56 10.01 9.46 9.82 8.76 7.92 8.31 9.763333333 8.33 1241.53 1120.76 1135.44 1141.543333 1165.91 0.882590238 0.016881964 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol GO:0042803///protein homodimerization activity+++GO:0062069///GARP complex binding GO:0008150///biological_process 75099 75099 'Lysmd4' mRNA 483 524 478 9.56 10.83 10.76 6.13 5.65 4.58 10.38333333 5.453333333 349 352 282 495 327.6666667 9.44E-06 -0.606511928 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75104 75104 'Mmd2' mRNA 180.91 151.19 146.45 2.55 1.91 2.25 0.51 1.05 0.78 2.236666667 0.78 77.07 99.36 75.09 159.5166667 83.84 9.58E-05 -0.934899711 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0004672///protein kinase activity GO:0006468///protein phosphorylation+++GO:0019835///cytolysis+++GO:0032880///regulation of protein localization+++GO:0045666///positive regulation of neuron differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction 75106 75106 '4930519F16Rik' mRNA 5 11 9 0.17 0.39 0.27 0.05 0 0.08 0.276666667 0.043333333 1 0 3 8.333333333 1.333333333 0.054940955 -2.658327499 GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity GO:0006508///proteolysis 75124 75124 'Nxnl2' mRNA 22 21 10 1.18 1.1 0.56 1.97 1.91 2.24 0.946666667 2.04 42 41 47 17.66666667 43.33333333 0.007425518 1.293801012 GO:0007600///sensory perception+++GO:0007601///visual perception+++GO:0007608///sensory perception of smell+++GO:0045494///photoreceptor cell maintenance 75129 75129 '4930524J08Rik' mRNA 13 15 12 1.48 1.7 1.45 1 1.03 1.34 1.543333333 1.123333333 10 10 13 13.33333333 11 0.755041601 -0.285822708 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75137 75137 'Rprd2' mRNA 1159 1214 872 8.91 10.1 7.54 6.62 6.32 6.53 8.85 6.49 957 839 871 1081.666667 889 0.009718584 -0.289567042 "GO:0016591///RNA polymerase II, holoenzyme" GO:0000993///RNA polymerase II complex binding GO:0031124///mRNA 3'-end processing 75141 75141 'Rasd2' mRNA 2301 2234 827 45.2 43.19 17.23 3.21 3.46 4.27 35.20666667 3.646666667 188 198 242 1787.333333 209.3333333 4.97E-12 -3.083607586 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031681///G-protein beta-subunit binding+++GO:0043548///phosphatidylinositol 3-kinase binding "GO:0001963///synaptic transmission, dopaminergic+++GO:0007165///signal transduction+++GO:0007610///behavior+++GO:0007626///locomotory behavior+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033235///positive regulation of protein sumoylation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0051897///positive regulation of protein kinase B signaling" 75146 75146 'Mfsd13a' mRNA 373 385 377 9.19 9.34 9.85 8.08 7.48 8.14 9.46 7.9 377 341 368 378.3333333 362 0.660362206 -0.07644495 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75172 75172 'Ccdc146' mRNA 168 164 137 2.69 2.58 2.33 0.38 0.24 0.22 2.533333333 0.28 28 17 16 156.3333333 20.33333333 7.20E-22 -2.953819733 GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 75173 75173 'Tex38' mRNA 42.71 38.86 41.16 0.49 0.91 0.97 0.44 0.29 0.38 0.79 0.37 19.49 24.57 25.37 40.91 23.14333333 0.071312549 -0.842759878 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function 75178 75178 'Meiob' mRNA 36.62 28.9 16.6 1.2 1.05 0.58 0.3 0.37 0.48 0.943333333 0.383333333 10.61 11.8 14.03 27.37333333 12.14666667 0.057224548 -1.191555892 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0016787///hydrolase activity GO:0000712///resolution of meiotic recombination intermediates+++GO:0000724///double-strand break repair via homologous recombination+++GO:0007129///synapsis+++GO:0007140///male meiotic nuclear division+++GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0009566///fertilization+++GO:0051321///meiotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 75180 75180 'Tmem269' mRNA 30 21 27 0.77 0.57 0.8 0.25 0.65 0.54 0.713333333 0.48 8 29 24 26 20.33333333 0.621721119 -0.360628809 GO:0016020///membrane+++GO:0016021///integral component of membrane 751864 751864 'Gm9733' mRNA 3 2 2 0.37 0.17 0.26 3.27 3.28 3.75 0.266666667 3.433333333 43 40 41 2.333333333 41.33333333 1.92E-08 4.136199127 04380///Osteoclast differentiation GO:0005886///plasma membrane GO:0003674///molecular_function GO:0050766///positive regulation of phagocytosis+++GO:0050870///positive regulation of T cell activation 751865 751865 'Sap25' mRNA 1302 1273 1156 77.01 74.42 72.54 26.87 27.29 25.66 74.65666667 26.60666667 521 516 481 1243.666667 506 4.00E-46 -1.30768542 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 75196 75196 'Ankrd7' mRNA 54 53.09 33 0.38 0.37 0.25 0.1 0.04 0.14 0.333333333 0.093333333 17 7 22 46.69666667 15.33333333 0.001639217 -1.611344547 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome GO:0003674///molecular_function GO:0001835///blastocyst hatching 75202 75202 'Spaca6' mRNA 1124 1067 861 9.96 9.31 8.25 8.85 7.74 8.57 9.173333333 8.386666667 1054 862 940 1017.333333 952 0.398332236 -0.104742619 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0007338///single fertilization+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization 75209 75209 'Sv2c' mRNA 446 460 420 3.79 3.52 3.09 1.11 1.25 1.14 3.466666667 1.166666667 155.01 159 137.02 442 150.3433333 5.23E-26 -1.566598553 04512///ECM-receptor interaction GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0045202///synapse GO:0022857///transmembrane transporter activity GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport 75210 75210 'Prr3' mRNA 384 369.02 391.02 13.46 13.8 15.19 12 13.13 12.78 14.15 12.63666667 421 443 418 381.3466667 427.3333333 0.32171334 0.151511816 GO:0005575///cellular_component GO:0046872///metal ion binding GO:0008150///biological_process 75212 75212 'Rnf121' mRNA 822.63 955.55 789.33 20.44 23.41 20.85 19.66 19.09 22.71 21.56666667 20.48666667 909.81 858.38 1015.35 855.8366667 927.8466667 0.383738352 0.107176707 GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030968///endoplasmic reticulum unfolded protein response 75216 75216 'Cep128' mRNA 181 176 180 2.02 1.94 2.17 1.99 1.66 1.66 2.043333333 1.77 172 166 155 179 164.3333333 0.565800506 -0.136247412 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0120103///centriolar subdistal appendage GO:0003674///molecular_function GO:0008104///protein localization 75219 75219 'Dusp18' mRNA 1188.92 1383 1267 13.75 15.73 15.55 9.34 8.22 8.65 15.01 8.736666667 929.86 799 833.88 1279.64 854.2466667 3.14E-10 -0.596629796 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0031304///intrinsic component of mitochondrial inner membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0006612///protein targeting to membrane+++GO:0006626///protein targeting to mitochondrion+++GO:0016311///dephosphorylation+++GO:0033365///protein localization to organelle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0046677///response to antibiotic 75221 75221 'Dpp3' mRNA 1194 1215 1149 24.79 24.82 25.31 34.69 33.72 32.73 24.97333333 33.71333333 1919 1816 1761 1186 1832 1.72E-16 0.615500338 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis 75234 75234 'Rnf19b' mRNA 156 133 134 3.29 2.73 3.02 5.19 4.88 6.09 3.013333333 5.386666667 280 256 320 141 285.3333333 2.48E-08 1.005566315 GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044194///cytolytic granule GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032609///interferon-gamma production+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0051865///protein autoubiquitination 75258 75258 '4930563M21Rik' mRNA 8 8 16 0.17 0.16 0.31 0.1 0.3 0.16 0.213333333 0.186666667 6 16 8 10.66666667 10 0.913490217 -0.113839246 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75266 75266 'Tomm20l' mRNA 3 5 6 0.39 0.64 0.82 0.56 0.12 0.47 0.616666667 0.383333333 5 1 4 4.666666667 3.333333333 0.753790448 -0.513518349 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane GO:0008320///protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix 75273 75273 'Pelp1' mRNA 516 511 322 8.17 7.96 5.41 7.89 7.17 7.63 7.18 7.563333333 574 509 537 449.6666667 540 0.11177485 0.260477621 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin+++GO:0071339///MLL1 complex GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0032183///SUMO binding+++GO:0047485///protein N-terminus binding+++GO:0051117///ATPase binding GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071391///cellular response to estrogen stimulus 75276 75276 'Ppp1r1c' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043086///negative regulation of catalytic activity+++GO:0051301///cell division 75284 75284 'Bcdin3d' mRNA 226 179 221 10.8 8.45 11.21 5.79 7.68 7.88 10.15333333 7.116666667 139 180 183 208.6666667 167.3333333 0.14506729 -0.331239657 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0010586///miRNA metabolic process+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0061715///miRNA 2'-O-methylation+++GO:2000632///negative regulation of pre-miRNA processing 75288 75288 'Slc35f4' mRNA 16 7 6 0.26 0.1 0.05 0.04 0.04 0.09 0.136666667 0.056666667 3 2 4 9.666666667 3 0.132725061 -1.69179689 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0022857///transmembrane transporter activity GO:0008150///biological_process+++GO:0055085///transmembrane transport 75291 75291 'Zbtb3' mRNA 86 74 109 2.39 1.91 3.31 1.82 2.2 2.53 2.536666667 2.183333333 76 88 96 89.66666667 86.66666667 0.863090843 -0.067246035 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II 75292 75292 'Prkd3' mRNA 632 665 566 5.9 5.97 5.42 5.55 5.15 5.26 5.763333333 5.32 693 606 651 621 650 0.69731818 0.055479736 04015///Rap1 signaling pathway+++04925///Aldosterone synthesis and secretion+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004697///protein kinase C activity+++GO:0004698///calcium-dependent protein kinase C activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0089700///protein kinase D signaling 75296 75296 'Cep43' mRNA 799.13 807.99 863.6 14.1 13.97 16.23 10.38 9.93 10.47 14.76666667 10.26 675.08 630.76 659.37 823.5733333 655.07 0.001549245 -0.344678882 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm GO:0019901///protein kinase binding+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0042803///protein homodimerization activity GO:0006469///negative regulation of protein kinase activity+++GO:0008284///positive regulation of cell proliferation+++GO:0030030///cell projection organization+++GO:0030307///positive regulation of cell growth+++GO:0030335///positive regulation of cell migration+++GO:0034453///microtubule anchoring+++GO:0061099///negative regulation of protein tyrosine kinase activity 75302 75302 'Asxl2' mRNA 1409.67 1379.37 1356.91 7.1 6.6 7.12 5.8 5.6 6.03 6.94 5.81 1364.21 1275.83 1301.47 1381.983333 1313.836667 0.36078091 -0.085224403 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035517///PR-DUB complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0046872///metal ion binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003007///heart morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007507///heart development+++GO:0007512///adult heart development+++GO:0009887///animal organ morphogenesis+++GO:0010884///positive regulation of lipid storage+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048704///embryonic skeletal system morphogenesis+++GO:1900159///positive regulation of bone mineralization involved in bone maturation+++GO:1902466///positive regulation of histone H3-K27 trimethylation" 75304 75304 '4930563E22Rik' mRNA 131.7 147.25 109.31 2.17 2.39 1.91 1.28 0.83 1.36 2.156666667 1.156666667 89.54 56.64 91.83 129.42 79.33666667 0.008361211 -0.723082088 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75305 75305 'Ankrd53' mRNA 0 1 0 0 0.03 0 0 0.03 0 0.01 0.01 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0031116///positive regulation of microtubule polymerization+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization+++GO:1902412///regulation of mitotic cytokinesis 75311 75311 '4930550C14Rik' mRNA 47 42 34 0.82 0.78 0.66 0.47 0.4 0.39 0.753333333 0.42 31 26 25 41 27.33333333 0.201927217 -0.593738498 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane GO:0005515///protein binding GO:0090258///negative regulation of mitochondrial fission+++GO:1903215///negative regulation of protein targeting to mitochondrion 75316 75316 'Taf1d' mRNA 606.99 535.89 620.76 13.11 11.22 13.8 14.63 15.22 15.51 12.71 15.12 717.11 724.21 726.07 587.88 722.4633333 0.019424493 0.284879794 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005668///RNA polymerase transcription factor SL1 complex+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0034451///centriolar satellite+++GO:0072686///mitotic spindle GO:0003677///DNA binding+++GO:0042802///identical protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 75317 75317 'Parpbp' mRNA 4 6 0 0.09 0.14 0 0.95 0.91 0.82 0.076666667 0.893333333 67 54 55 3.333333333 58.66666667 6.98E-11 4.135802726 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 75320 75320 'Etnk1' mRNA 3131.63 3071.03 2693.74 27.33 26.15 24.62 20.49 18.68 19.98 26.03333333 19.71666667 2723.88 2434.59 2557.24 2965.466667 2571.903333 0.001612182 -0.215750488 00564///Glycerophospholipid metabolism GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0004305///ethanolamine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0016310///phosphorylation 75328 75328 'Fam243' mRNA 0 1 0 0 0.02 0 0.13 0 0.02 0.006666667 0.05 7 0 1 0.333333333 2.666666667 0.311731317 2.858540227 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75329 75329 'Atf7ip2' mRNA 3 3 9 0.04 0.03 0.13 0.11 0 0.05 0.066666667 0.053333333 7 0 2 5 3 0.653370172 -0.794606579 GO:0005634///nucleus+++GO:0005667///transcription factor complex GO:0003674///molecular_function+++GO:0003712///transcription coregulator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process+++GO:0090309///positive regulation of methylation-dependent chromatin silencing" 75338 75338 'Ccdc83' mRNA 13 16 21 0.47 0.67 0.81 0.09 0.11 0.04 0.65 0.08 3 3 1 16.66666667 2.333333333 0.002556709 -2.858348464 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75339 75339 'Mphosph8' mRNA 792 724 767 14.8 13.35 15.24 14.3 16.03 14.59 14.46333333 14.97333333 881 962 867 761 903.3333333 0.033951187 0.235147514 GO:0000786///nucleosome+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0035064///methylated histone binding "GO:0044030///regulation of DNA methylation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:2000812///regulation of barbed-end actin filament capping" 75341 75341 '4930564C03Rik' mRNA 2 0 1 0.1 0 0.06 0.05 0 0.19 0.053333333 0.08 1 0 4 1 1.666666667 0.822190853 0.719029361 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75345 75345 'Slamf7' mRNA 15 9 3 0.23 0.12 0.05 5.03 4.63 4.57 0.133333333 4.743333333 345 306 304 9 318.3333333 2.51E-52 5.136553357 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0032814///regulation of natural killer cell activation+++GO:0042110///T cell activation+++GO:0045087///innate immune response 75352 75352 'Magea13' mRNA 0 0 1 0 0 0.04 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 75368 75368 '4930558K02Rik' mRNA 12 19 10 0.18 0.29 0.21 0.28 0.14 0.04 0.226666667 0.153333333 13 10 3 13.66666667 8.666666667 0.483201007 -0.663513694 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75387 75387 'Sirt4' mRNA 321.35 281.43 302.67 9.95 8.77 10.01 10.33 11.89 11.65 9.576666667 11.29 426.35 469.54 457.56 301.8166667 451.15 5.19E-05 0.568933524 00760///Nicotinate and nicotinamide metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019213///deacetylase activity+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0046872///metal ion binding+++GO:0047708///biotinidase activity+++GO:0061690///lipoamidase activity+++GO:0070403///NAD+ binding GO:0000820///regulation of glutamine family amino acid metabolic process+++GO:0006471///protein ADP-ribosylation+++GO:0006476///protein deacetylation+++GO:0006541///glutamine metabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0034983///peptidyl-lysine deacetylation+++GO:0046322///negative regulation of fatty acid oxidation+++GO:0046676///negative regulation of insulin secretion+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0071456///cellular response to hypoxia+++GO:0072350///tricarboxylic acid metabolic process+++GO:1903217///negative regulation of protein processing involved in protein targeting to mitochondrion+++GO:1904182///regulation of pyruvate dehydrogenase activity 75388 75388 'Boll' mRNA 0 3 0 0 0.05 0 0 0.03 0 0.016666667 0.01 0 1 0 1 0.333333333 0.753543289 -1.448551084 GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0090543///Flemming body GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008494///translation activator activity GO:0006417///regulation of translation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045948///positive regulation of translational initiation+++GO:0051321///meiotic cell cycle+++GO:0070935///3'-UTR-mediated mRNA stabilization 75396 75396 'Spp2' mRNA 2 0 0 0.29 0 0 0 0 0 0.096666667 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 GO:0005576///extracellular region+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0046849///bone remodeling+++GO:0065003///protein-containing complex assembly 75398 75398 'Mrpl32' mRNA 611 626 588 54.94 55.83 56.11 63.66 67.09 60.58 55.62666667 63.77666667 810 831 744 608.3333333 795 3.70E-04 0.375003421 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit GO:0003735///structural constituent of ribosome GO:0006412///translation 75404 75404 'Arhgap36' mRNA 0 1 1 0 0.02 0.02 0.12 0.09 0.05 0.013333333 0.086666667 7 5 3 0.666666667 5 0.11777643 2.884952596 GO:0003674///molecular_function+++GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 75406 75406 'Ndufs7' mRNA 3805 3702 3628 338.19 325.72 343.55 267.98 277.7 278.25 335.82 274.6433333 3427 3458 3446 3711.666667 3443.666667 0.073899317 -0.119790657 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0070469///respiratory chain+++GO:0097060///synaptic membrane "GO:0002020///protease binding+++GO:0003954///NADH dehydrogenase activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0048038///quinone binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" "GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0009060///aerobic respiration+++GO:0015990///electron transport coupled proton transport+++GO:0032981///mitochondrial respiratory chain complex I assembly" 75409 75409 'Slitrk5' mRNA 103 79 48 1.24 0.91 0.61 0.34 0.4 0.39 0.92 0.376666667 33 37 36 76.66666667 35.33333333 0.002848998 -1.117296422 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0045202///synapse GO:0003674///molecular_function GO:0007268///chemical synaptic transmission+++GO:0007409///axonogenesis+++GO:0007625///grooming behavior+++GO:0009410///response to xenobiotic stimulus+++GO:0021756///striatum development+++GO:0030534///adult behavior+++GO:0043588///skin development+++GO:0048813///dendrite morphogenesis+++GO:0051965///positive regulation of synapse assembly+++GO:0072359///circulatory system development+++GO:1905606///regulation of presynapse assembly 75410 75410 'Kmt2b' mRNA 399 453 341 3.62 3.94 3.32 3.35 3.15 3.06 3.626666667 3.186666667 423 384 385 397.6666667 397.3333333 0.96147564 -0.009406764 00310///Lysine degradation GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex GO:0003677///DNA binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0045322///unmethylated CpG binding+++GO:0046872///metal ion binding "GO:0001541///ovarian follicle development+++GO:0006325///chromatin organization+++GO:0006346///methylation-dependent chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007613///memory+++GO:0009994///oocyte differentiation+++GO:0016458///gene silencing+++GO:0016571///histone methylation+++GO:0030728///ovulation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0044648///histone H3-K4 dimethylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051568///histone H3-K4 methylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0097692///histone H3-K4 monomethylation" 75415 75415 'Arhgap12' mRNA 1006 969 1030 10.91 10.34 11.8 9.84 8.72 8.71 11.01666667 9.09 1046 906 901 1001.666667 951 0.454101746 -0.08979247 GO:0001891///phagocytic cup+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005096///GTPase activator activity "GO:0002011///morphogenesis of an epithelial sheet+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0007165///signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051058///negative regulation of small GTPase mediated signal transduction" 75416 75416 'Nop14' mRNA 598 602 555 12.25 12.14 12.06 12.61 12.29 12.29 12.15 12.39666667 708 674 668 585 683.3333333 0.05357471 0.213076575 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0030692///Noc4p-Nop14p complex+++GO:0032040///small-subunit processome GO:0019899///enzyme binding+++GO:0030515///snoRNA binding GO:0006364///rRNA processing+++GO:0030490///maturation of SSU-rRNA+++GO:0042254///ribosome biogenesis+++GO:0042274///ribosomal small subunit biogenesis 75420 75420 'Secisbp2' mRNA 539 505 516 8.87 8.18 9.01 8.41 8.38 8.7 8.686666667 8.496666667 588 572 589 520 583 0.231586426 0.152611688 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding "GO:0001514///selenocysteine incorporation+++GO:0021756///striatum development+++GO:0048666///neuron development+++GO:1904571///positive regulation of selenocysteine incorporation+++GO:2000623///negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay" 75422 75422 'Mettl5' mRNA 345.74 374.62 360.02 20.56 21.99 22.93 21.18 20.08 18.29 21.82666667 19.85 392.05 362.67 333.51 360.1266667 362.7433333 0.997298102 -0.002302685 GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity+++GO:0008988///rRNA (adenine-N6-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:1904047///S-adenosyl-L-methionine binding GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0045727///positive regulation of translation+++GO:0048863///stem cell differentiation 75423 75423 'Arl5a' mRNA 672 534 643 6.87 5.37 6.98 7.23 5.68 6.99 6.406666667 6.633333333 814 624 762 616.3333333 733.3333333 0.105203697 0.233930932 GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:1903292///protein localization to Golgi membrane 75424 75424 'Zfp820' mRNA 27.01 35 32 0.4 0.51 0.5 0.36 0.33 0.33 0.47 0.34 28 25 25 31.33666667 26 0.624519224 -0.282315849 GO:0005575///cellular_component+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008150///biological_process" 75425 75425 'Tti1' mRNA 393 431 419 5.53 5.97 6.28 6.02 5.28 6.44 5.926666667 5.913333333 492 420 509 414.3333333 473.6666667 0.225085913 0.179677651 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0031932///TORC2 complex+++GO:0070209///ASTRA complex GO:0003674///molecular_function GO:0006338///chromatin remodeling+++GO:0032006///regulation of TOR signaling 75426 75426 'Igfbpl1' mRNA 0 1 2 0 0.02 0.04 0.07 0.04 0.09 0.02 0.066666667 4 2 5 1 3.666666667 0.352822336 1.838972024 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005520///insulin-like growth factor binding GO:0001558///regulation of cell growth+++GO:0009966///regulation of signal transduction 75429 75429 'Fam183b' mRNA 758 783 829 107.25 110.31 124.3 15.37 14.11 11.04 113.9533333 13.50666667 124 111 85 790 106.6666667 3.13E-83 -2.904179784 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base GO:0005515///protein binding GO:0008150///biological_process 75430 75430 'Anapc15' mRNA 670.04 732.22 713.63 15.5 15.62 17.9 27.83 26.81 28.27 16.34 27.63666667 560.43 544.88 589.24 705.2966667 564.85 0.003178855 -0.333645304 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005680///anaphase-promoting complex GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0090266///regulation of mitotic cell cycle spindle assembly checkpoint 75434 75434 'Fam166c' mRNA 698 725 742 67.08 69.03 75.62 6.82 6.41 5.42 70.57666667 6.216666667 80 74 63 721.6666667 72.33333333 1.45E-100 -3.332714329 GO:0003674///molecular_function GO:0008150///biological_process 75444 75444 'Ccdc192' mRNA 27 19 26 1.95 1.33 2.05 1.46 1.11 1.27 1.776666667 1.28 25 18 19 24 20.66666667 0.740213982 -0.234161037 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75452 75452 'Ascc2' mRNA 1781 1984 1786 19.23 21.03 20.42 16 17.64 16.07 20.22666667 16.57 1710 1839 1662 1850.333333 1737 0.274376963 -0.101533959 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0099053///activating signal cointegrator 1 complex GO:0043130///ubiquitin binding "GO:0006281///DNA repair+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0072344///rescue of stalled ribosome+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process" 75454 75454 'Phpt1' mRNA 1181 1073 1122 145.61 134.33 147.15 106.36 103.59 97.82 142.3633333 102.59 991 950 891 1125.333333 944 0.006167901 -0.266622773 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0019855///calcium channel inhibitor activity+++GO:0044325///ion channel binding+++GO:0101006///protein histidine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0035971///peptidyl-histidine dephosphorylation+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0051350///negative regulation of lyase activity+++GO:2000147///positive regulation of cell motility+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:2000984///negative regulation of ATP citrate synthase activity 75456 75456 'Prps1l1' mRNA 0 0 2 0 0 0.07 0 0.15 0 0.023333333 0.05 0 5 0 0.666666667 1.666666667 0.736236787 1.274623002 00030///Pentose phosphate pathway+++00230///Purine metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0002189///ribose phosphate diphosphokinase complex+++GO:0005737///cytoplasm GO:0000287///magnesium ion binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0008584///male gonad development+++GO:0009116///nucleoside metabolic process+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0009165///nucleotide biosynthetic process+++GO:0016310///phosphorylation+++GO:0044249///cellular biosynthetic process 75458 75458 'Cklf' mRNA 159 158 183 11.11 9.39 13.91 32.61 34.57 37 11.47 34.72666667 428 411 446 166.6666667 428.3333333 2.58E-18 1.346885552 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity+++GO:0008009///chemokine activity GO:0006935///chemotaxis+++GO:0030593///neutrophil chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0032940///secretion by cell+++GO:0048246///macrophage chemotaxis+++GO:0048247///lymphocyte chemotaxis 75459 75459 'Syce3' mRNA 1 0 0 0.2 0 0 0 0 0 0.066666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000801///central element+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome GO:0005515///protein binding GO:0007049///cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0007283///spermatogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle 75462 75462 '1700001C19Rik' mRNA 0 3.28 2.17 0 0.26 0.1 0.63 0.07 0.23 0.12 0.31 11.28 1 4.16 1.816666667 5.48 0.342089018 1.648053166 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75465 75465 'Dynlrb2' mRNA 863 849 829 139.38 137.05 142.16 14.48 19.75 15.34 139.53 16.52333333 102 135 104 847 113.6666667 2.26E-95 -2.908137878 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005868///cytoplasmic dynein complex+++GO:0005874///microtubule+++GO:0030286///dynein complex GO:0005515///protein binding+++GO:0045505///dynein intermediate chain binding GO:0007018///microtubule-based movement 75467 75467 'Stpg4' mRNA 1 5 5 0.06 0.39 0.42 0.21 0.21 0.21 0.29 0.21 3 4 5 3.666666667 4 0.949887853 0.108078561 GO:0001939///female pronucleus+++GO:0001940///male pronucleus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0042585///germinal vesicle GO:0003682///chromatin binding+++GO:0042393///histone binding GO:0006325///chromatin organization+++GO:0007275///multicellular organism development+++GO:0044727///DNA demethylation of male pronucleus+++GO:0090116///C-5 methylation of cytosine+++GO:1901537///positive regulation of DNA demethylation 75469 75469 'Spata19' mRNA 0 2 1 0 0.22 0.12 0 0.1 0 0.113333333 0.033333333 0 1 0 1 0.333333333 0.727684624 -1.487414893 GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 75472 75472 'Cfap126' mRNA 1750 1686 1513 118.9 113.46 109.25 11.15 10.98 10.17 113.87 10.76666667 187 182 166 1649.666667 178.3333333 1.63E-207 -3.219564062 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0030030///cell projection organization+++GO:0044782///cilium organization 75475 75475 'Oplah' mRNA 876.83 933.97 875.41 11.64 12.26 12.37 15.74 14 15.27 12.09 15.00333333 1356.58 1176.26 1275.26 895.4033333 1269.366667 2.47E-08 0.491688115 00480///Glutathione metabolism GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017168///5-oxoprolinase (ATP-hydrolyzing) activity+++GO:0042802///identical protein binding GO:0006749///glutathione metabolic process 75480 75480 '1700003F12Rik' mRNA 13 14 9 1.24 1.33 0.91 0.7 0.6 0.61 1.16 0.636666667 8 7 7 12 7.333333333 0.438064346 -0.715765554 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75482 75482 'Hspb9' mRNA 3 1 0 0.34 0.11 0 0.1 0.51 0.1 0.15 0.236666667 1 5 1 1.333333333 2.333333333 0.748070175 0.832120797 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 75483 75483 'Cox8c' mRNA 1 0 0 0.18 0 0 0 0 0 0.06 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045277///respiratory chain complex IV GO:0004129///cytochrome-c oxidase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen" 75485 75485 '1700010B08Rik' mRNA 1 3 0 0.07 0.22 0 0.26 0.13 0.13 0.096666667 0.173333333 4 2 2 1.333333333 2.666666667 0.662566835 1.011716704 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75495 75495 'Morn5' mRNA 121 119 105 12.6 12.31 11.61 2.83 1.97 1.8 12.17333333 2.2 31 21 19 115 23.66666667 9.50E-13 -2.292919996 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75502 75502 'Cmtm2b' mRNA 0 1 1 0 0.07 0.08 0.33 0.67 0.74 0.05 0.58 5 10 11 0.666666667 8.666666667 0.018218733 3.690788945 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005125///cytokine activity GO:0006935///chemotaxis+++GO:0007165///signal transduction 75504 75504 '1700013F07Rik' mRNA 59 42 54 7.67 5.44 7.45 1.71 0.82 1.18 6.853333333 1.236666667 15 7 10 51.66666667 10.66666667 3.23E-06 -2.295338983 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0015232///heme transporter activity+++GO:0020037///heme binding GO:0097037///heme export 75507 75507 'Pou5f2' mRNA 102 84 67 4.37 3.55 3.05 2.05 2.03 2.35 3.656666667 2.143333333 55 53 61 84.33333333 56.33333333 0.067658562 -0.588464024 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 75512 75512 'Gpx6' mRNA 67 69 63 3.37 3.47 3.22 1.81 1.55 1.84 3.353333333 1.733333333 43 36 41 66.33333333 40 0.034480777 -0.741506262 00480///Glutathione metabolism+++00590///Arachidonic acid metabolism+++04918///Thyroid hormone synthesis+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005576///extracellular region GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity+++GO:0016491///oxidoreductase activity GO:0006979///response to oxidative stress+++GO:0098869///cellular oxidant detoxification 75516 75516 'Ttc32' mRNA 181 228 203 11.57 14.42 13.77 11.65 16.13 13.1 13.25333333 13.62666667 209 282 227 204 239.3333333 0.31554991 0.22138457 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75524 75524 'Tex48' mRNA 0 0 3 0 0 0.34 0 0 0 0.113333333 0 0 0 0 1 0 0.625198426 -2.527571966 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75526 75526 'Eppin' mRNA 0 1 1 0 0.09 0.1 0 0 0 0.063333333 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0032991///protein-containing complex GO:0003674///molecular_function+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0042742///defense response to bacterium 75528 75528 'Tex29' mRNA 1 1 0 0.09 0.04 0 0.08 0 0.08 0.043333333 0.053333333 1 0 1 0.666666667 0.666666667 0.998591786 0.007987197 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75530 75530 'Lyrm7' mRNA 163 150 139 2.86 2.59 2.58 3.17 3.15 3.34 2.676666667 3.22 208.04 197 198 150.6666667 201.0133333 0.03939729 0.405272778 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0045333///cellular respiration 75533 75533 'Nme5' mRNA 575 594 610 45.56 46.62 51.29 9.83 10.58 9.53 47.82333333 9.98 142 149 133 593 141.3333333 1.48E-48 -2.082202091 GO:0005576///extracellular region+++GO:0005929///cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection GO:0003674///molecular_function+++GO:0004550///nucleoside diphosphate kinase activity GO:0000302///response to reactive oxygen species+++GO:0003351///epithelial cilium movement+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0021591///ventricular system development+++GO:0030154///cell differentiation+++GO:0048515///spermatid differentiation+++GO:0060271///cilium assembly+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 75538 75538 'Fam71e1' mRNA 264 285.68 266 8.31 9.71 9.52 3.16 2.36 3.12 9.18 2.88 98.23 64.06 88.07 271.8933333 83.45333333 1.24E-17 -1.718883213 GO:0003674///molecular_function GO:0008150///biological_process 75540 75540 'Fpgt' mRNA 591 635 586 8.94 9.44 9.49 6.68 6.12 5.89 9.29 6.23 500 451 433 604 461.3333333 6.37E-04 -0.400883837 00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005575///cellular_component+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005525///GTP binding+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0016779///nucleotidyltransferase activity+++GO:0047341///fucose-1-phosphate guanylyltransferase activity" GO:0008150///biological_process 75541 75541 'Nat8f4' mRNA 883.01 946.03 899.68 15.5 16.29 16.61 10.28 10 9.85 16.13333333 10.04333333 670.33 614.59 624.54 909.5733333 636.4866667 6.65E-08 -0.528309588 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0006749///glutathione metabolic process+++GO:0010628///positive regulation of gene expression+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 75547 75547 'Akap13' mRNA 4002.97 3847.76 3349.01 13.87 13.32 12.76 12 11.16 11.64 13.31666667 11.6 3718.76 3281.92 3504.63 3733.246667 3501.77 0.167557773 -0.102415647 "04928///Parathyroid hormone synthesis, secretion and action+++05163///Human cytomegalovirus infection" GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005938///cell cortex+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0004691///cAMP-dependent protein kinase activity+++GO:0005078///MAP-kinase scaffold activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0016301///kinase activity+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0051018///protein kinase A binding+++GO:0060090///molecular adaptor activity GO:0006468///protein phosphorylation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0016310///phosphorylation+++GO:0035023///regulation of Rho protein signal transduction+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050790///regulation of catalytic activity+++GO:0051168///nuclear export+++GO:0055007///cardiac muscle cell differentiation+++GO:0060297///regulation of sarcomere organization+++GO:0060348///bone development+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0071875///adrenergic receptor signaling pathway+++GO:0086023///adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process+++GO:1900169///regulation of glucocorticoid mediated signaling pathway 75552 75552 'Paqr9' mRNA 226 259 223 1.42 1.59 1.48 0.17 0.18 0.17 1.496666667 0.173333333 31 32 30 236 31 9.06E-34 -2.938620857 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity 75553 75553 'Zc3h14' mRNA 1467.77 1524.86 1165.95 22.13 22.53 18.62 12.62 14.92 14.33 21.09333333 13.95666667 965.14 1091.89 1056.59 1386.193333 1037.873333 2.68E-05 -0.422803639 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0032839///dendrite cytoplasm+++GO:1904115///axon cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0008143///poly(A) binding+++GO:0046872///metal ion binding GO:0043488///regulation of mRNA stability+++GO:1900364///negative regulation of mRNA polyadenylation 75555 75555 'Nscme3l' mRNA 5 7 1 0.31 0.43 0.07 0.05 0.06 0.11 0.27 0.073333333 1 1 2 4.333333333 1.333333333 0.343893384 -1.684641593 GO:0005634///nucleus GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 75556 75556 'Cfap161' mRNA 2015 2000 1985 89.06 87.6 92.98 6.19 5.12 5.82 89.88 5.71 161 130 142 2000 144.3333333 8.95E-274 -3.805902083 GO:0005575///cellular_component+++GO:0031514///motile cilium GO:0003674///molecular_function GO:0008150///biological_process+++GO:0060271///cilium assembly 75558 75558 'Spata45' mRNA 3 3 2 0.26 0.26 0.19 0.15 0.08 0.08 0.236666667 0.103333333 2 1 1 2.666666667 1.333333333 0.638641686 -1.009843036 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75560 75560 'Ep400' mRNA 1824 1826 1634 8.74 8.59 8.29 7.62 6.66 7.73 8.54 7.336666667 1823 1563 1793 1761.333333 1726.333333 0.705241135 -0.040027438 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0035267///NuA4 histone acetyltransferase complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0070615///nucleosome-dependent ATPase activity+++GO:1990405///protein antigen binding GO:0006325///chromatin organization+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation 75563 75563 'Dnali1' mRNA 221 271 237 6 7.25 6.83 0.95 0.97 0.88 6.693333333 0.933333333 40 40 36 243 38.66666667 2.10E-30 -2.663004548 05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05022///Pathways of neurodegeneration - multiple diseases GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0030175///filopodium+++GO:0030286///dynein complex+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0097546///ciliary base+++GO:0097729///9+2 motile cilium GO:0045504///dynein heavy chain binding GO:0003341///cilium movement 75564 75564 'Rsph9' mRNA 1523 1661 1516 101.4 107.55 104.74 35.91 40.92 40.4 104.5633333 39.07666667 621 687 683 1566.666667 663.6666667 4.38E-44 -1.249391023 GO:0001534///radial spoke+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0060091///kinocilium+++GO:0097729///9+2 motile cilium GO:0005515///protein binding GO:0003341///cilium movement+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0044458///motile cilium assembly+++GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:1904158///axonemal central apparatus assembly 75565 75565 'Sgf29' mRNA 789 950 699 35.08 43.65 34.03 25.22 26.76 27.71 37.58666667 26.56333333 607 624 645 812.6666667 625.3333333 9.66E-04 -0.384648407 GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0070461///SAGA-type complex GO:0019899///enzyme binding+++GO:0035064///methylated histone binding+++GO:0047485///protein N-terminus binding GO:0006325///chromatin organization+++GO:0016573///histone acetylation+++GO:0043966///histone H3 acetylation 75568 75568 'Capsl' mRNA 433 502 546 30.19 34.65 40.37 6.51 5.85 4.62 35.07 5.66 106 93 74 493.6666667 91 2.81E-42 -2.456921534 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 75570 75570 'Nhej1' mRNA 102 108 98 4.33 4.53 4.42 10.21 7.32 7.23 4.426666667 8.253333333 276 193 189 102.6666667 219.3333333 5.57E-07 1.080861211 03450///Non-homologous end-joining GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032807///DNA ligase IV complex+++GO:0035861///site of double-strand break+++GO:0070419///nonhomologous end joining complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0045027///DNA end binding+++GO:0070182///DNA polymerase binding GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0030183///B cell differentiation+++GO:0030217///T cell differentiation+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0051103///DNA ligation involved in DNA repair 75571 75571 'Spata9' mRNA 6 11 11 0.36 0.66 0.54 0.46 0.83 0.55 0.52 0.613333333 9 16 10 9.333333333 11.66666667 0.762444283 0.310221859 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 75572 75572 'Acyp2' mRNA 332 409 389 31.74 40.26 40.47 31.86 33.48 36.12 37.49 33.82 371 372 400 376.6666667 381 0.990823096 0.003891976 00620///Pyruvate metabolism GO:0005739///mitochondrion GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0008150///biological_process 75573 75573 'Prr29' mRNA 3 0 3 0.2 0 0.18 0 0 0 0.126666667 0 0 0 0 2 0 0.284158268 -3.478122801 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75578 75578 'Fggy' mRNA 417 457 422 13.2 15.04 15.2 5.57 5.56 5.9 14.48 5.676666667 198 191 209 432 199.3333333 2.38E-15 -1.127323157 "GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0019150///D-ribulokinase activity" GO:0005975///carbohydrate metabolic process+++GO:0016310///phosphorylation+++GO:0019321///pentose metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0070050///neuron cellular homeostasis 75580 75580 'Zbtb4' mRNA 1583 1452 1204 10.73 9.75 8.61 5.99 5.29 5.9 9.696666667 5.726666667 1012 879 971 1413 954 2.04E-09 -0.575268687 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0010428///methyl-CpNpG binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated" 75581 75581 'Yipf7' mRNA 2 1 1 0.11 0.06 0.06 0.2 0.1 0 0.076666667 0.1 4 2 0 1.333333333 2 0.839092078 0.567165997 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus 75593 75593 'Malsu1' mRNA 449 389 397 29.69 26.57 28.13 28 29.16 28.65 28.13 28.60333333 413 393 397 411.6666667 401 0.781216872 -0.049846077 GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005829///cytosol GO:0043023///ribosomal large subunit binding GO:0017148///negative regulation of translation+++GO:0042254///ribosome biogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0070130///negative regulation of mitochondrial translation+++GO:0090071///negative regulation of ribosome biogenesis 75597 75597 'Ndufaf2' mRNA 285 279 225 29.98 29.02 24.93 27.2 28.68 26.77 27.97666667 27.55 293 304 281 263 292.6666667 0.428575221 0.146567763 04714///Thermogenesis GO:0005739///mitochondrion+++GO:0016020///membrane GO:0044877///protein-containing complex binding GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus 75599 75599 'Pcdh1' mRNA 400 421 181 5.04 5.12 2.33 2.71 3.23 3.53 4.163333333 3.156666667 249 287 316 334 284 0.406047783 -0.227467666 GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 75600 75600 'Calml4' mRNA 4371 4336 4128 348.31 343.1 350.82 109.08 113.11 107.64 347.41 109.9433333 1563 1577 1503 4278.333333 1547.666667 2.18E-124 -1.47825849 04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04070///Phosphatidylinositol signaling system+++04114///Oocyte meiosis+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04713///Circadian entrainment+++04720///Long-term potentiation+++04722///Neurotrophin signaling pathway+++04728///Dopaminergic synapse+++04740///Olfactory transduction+++04744///Phototransduction+++04745///Phototransduction - fly+++04750///Inflammatory mediator regulation of TRP channels+++04910///Insulin signaling pathway+++04912///GnRH signaling pathway+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04921///Oxytocin signaling pathway+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04925///Aldosterone synthesis and secretion+++04970///Salivary secretion+++04971///Gastric acid secretion+++05010///Alzheimer disease+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05031///Amphetamine addiction+++05034///Alcoholism+++05133///Pertussis+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++05167///Kaposi sarcoma-associated herpesvirus infection+++05170///Human immunodeficiency virus 1 infection+++05200///Pathways in cancer+++05214///Glioma+++05417///Lipid and atherosclerosis+++05418///Fluid shear stress and atherosclerosis GO:0005509///calcium ion binding+++GO:0030234///enzyme regulator activity GO:0050790///regulation of catalytic activity 75604 75604 'Tm4sf5' mRNA 117 105 91 7.72 6.85 6.37 5.87 4.67 5.9 6.98 5.48 102 79 99 104.3333333 93.33333333 0.593032778 -0.171019925 GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0034618///arginine binding GO:2000045///regulation of G1/S transition of mitotic cell cycle 75605 75605 'Kdm5b' mRNA 2008 2081 1584 16.92 17.26 14.2 9.36 11.25 11.33 16.12666667 10.64666667 1276 1501 1497 1891 1424.666667 4.11E-05 -0.413211743 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0034648///histone demethylase activity (H3-dimethyl-K4 specific)+++GO:0042393///histone binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:1990837///sequence-specific double-stranded DNA binding "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0007338///single fertilization+++GO:0009791///post-embryonic development+++GO:0010628///positive regulation of gene expression+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0042752///regulation of circadian rhythm+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060763///mammary duct terminal end bud growth+++GO:0060992///response to fungicide+++GO:0061038///uterus morphogenesis+++GO:0070306///lens fiber cell differentiation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000864///regulation of estradiol secretion" 75607 75607 'Wnk2' mRNA 2916 2716 2278 20.87 19.08 17.35 8.04 7.13 7.53 19.1 7.566666667 1280 1117 1172 2636.666667 1189.666667 5.96E-46 -1.157079364 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019869///chloride channel inhibitor activity+++GO:0019870///potassium channel inhibitor activity GO:0006468///protein phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010766///negative regulation of sodium ion transport+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0046777///protein autophosphorylation+++GO:0050801///ion homeostasis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1903288///positive regulation of potassium ion import+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 75608 75608 'Chmp4b' mRNA 115 129 114 4.19 4.63 4.41 4.25 5 4.19 4.41 4.48 134 154 128 119.3333333 138.6666667 0.432412557 0.207013817 04144///Endocytosis+++04217///Necroptosis GO:0000815///ESCRT III complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030117///membrane coat+++GO:0030496///midbody+++GO:0031902///late endosome membrane+++GO:0031982///vesicle+++GO:0098978///glutamatergic synapse GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0000281///mitotic cytokinesis+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0006900///vesicle budding from membrane+++GO:0006914///autophagy+++GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0010458///exit from mitosis+++GO:0010506///regulation of autophagy+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0031468///nuclear envelope reassembly+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0036438///maintenance of lens transparency+++GO:0039702///viral budding via host ESCRT complex+++GO:0046755///viral budding+++GO:0046761///viral budding from plasma membrane+++GO:0050792///regulation of viral process+++GO:0051258///protein polymerization+++GO:0060548///negative regulation of cell death+++GO:0061952///midbody abscission+++GO:0090148///membrane fission+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:0099175///regulation of postsynapse organization+++GO:1901215///negative regulation of neuron death+++GO:1901673///regulation of mitotic spindle assembly+++GO:1902188///positive regulation of viral release from host cell+++GO:1902902///negative regulation of autophagosome assembly 75610 75610 '2010109A12Rik' mRNA 3 2 0 0.44 0.29 0 0.26 0 0.4 0.243333333 0.22 2 0 3 1.666666667 1.666666667 0.998591786 0.010565186 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75612 75612 'Gns' mRNA 4014 4117 3146 56.18 56.68 46.7 64.99 77.61 74.92 53.18666667 72.50666667 5345 6235 5967 3759 5849 5.09E-14 0.633259473 00531///Glycosaminoglycan degradation+++04142///Lysosome GO:0005764///lysosome GO:0003824///catalytic activity+++GO:0005539///glycosaminoglycan binding+++GO:0008449///N-acetylglucosamine-6-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0043199///sulfate binding+++GO:0046872///metal ion binding GO:0030203///glycosaminoglycan metabolic process+++GO:0042340///keratan sulfate catabolic process 75613 75613 'Med25' mRNA 2822 2697 1901 59.63 56.19 40.89 28.48 35.77 30.34 52.23666667 31.53 1596 1950 1622 2473.333333 1722.666667 5.98E-06 -0.523772987 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex GO:0001223///transcription coactivator binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042974///retinoic acid receptor binding+++GO:0046965///retinoid X receptor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035563///positive regulation of chromatin binding+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0051726///regulation of cell cycle+++GO:0071158///positive regulation of cell cycle arrest+++GO:2001178///positive regulation of mediator complex assembly 75616 75616 'Smim15' mRNA 823 821 784 25.34 24.91 25.61 35.89 33.92 37.31 25.28666667 35.70666667 1340 1236 1348 809.3333333 1308 1.28E-15 0.680738452 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75617 75617 'Rps25' mRNA 4649.08 4291.63 5011.49 490.22 449.54 560.85 476.41 530.02 534.01 500.2033333 513.48 5163.14 5588.24 5582.63 4650.733333 5444.67 0.018261174 0.212380913 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0014069///postsynaptic density+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0000028///ribosomal small subunit assembly+++GO:0006364///rRNA processing+++GO:0042274///ribosomal small subunit biogenesis 75619 75619 'Fastkd2' mRNA 238 270 230 5.49 6.15 5.15 6.27 6.95 7.31 5.596666667 6.843333333 323 361 378 246 354 9.32E-04 0.516337616 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid GO:0003723///RNA binding+++GO:0019843///rRNA binding GO:0000963///mitochondrial RNA processing+++GO:0006396///RNA processing+++GO:0006915///apoptotic process+++GO:0032543///mitochondrial translation+++GO:0042254///ribosome biogenesis+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0070131///positive regulation of mitochondrial translation+++GO:0140208///apoptotic process in response to mitochondrial fragmentation+++GO:1902775///mitochondrial large ribosomal subunit assembly 75620 75620 'Kxd1' mRNA 843 872 765 42.47 43.38 40.89 40.73 45.5 41.31 42.24666667 42.51333333 928 1011 910 826.6666667 949.6666667 0.066388891 0.190971107 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0031083///BLOC-1 complex+++GO:0099078///BORC complex GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding GO:0006412///translation+++GO:0016192///vesicle-mediated transport+++GO:0032418///lysosome localization 75622 75622 'Spaca3' mRNA 5 1 2 0.42 0.08 0.18 0.15 0 0.23 0.226666667 0.126666667 2 0 3 2.666666667 1.666666667 0.766125047 -0.693102643 GO:0001669///acrosomal vesicle+++GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0031410///cytoplasmic vesicle+++GO:0036126///sperm flagellum+++GO:0043159///acrosomal matrix GO:0003796///lysozyme activity+++GO:0005515///protein binding GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0009566///fertilization+++GO:0035036///sperm-egg recognition 75623 75623 'Tex30' mRNA 126 155 106 6.35 8.01 5.61 14.42 12.22 11.3 6.656666667 12.64666667 317 275 236 129 276 1.97E-08 1.08921397 GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0008150///biological_process 75624 75624 'Metap1' mRNA 769 841 823 16.78 18.07 19.05 19.88 18.4 19.5 17.96666667 19.26 1048 947 995 811 996.6666667 0.004333079 0.284020282 GO:0005737///cytoplasm GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0006508///proteolysis+++GO:0070084///protein initiator methionine removal 75625 75625 'Mageh1' mRNA 490 518 367 20.94 21.85 16.64 16.49 14.46 15.89 19.81 15.61333333 443 379 413 458.3333333 411.6666667 0.313299229 -0.161658467 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 75627 75627 'Snapc1' mRNA 766 713 734 11.65 11.63 11.16 9.51 9.63 10.23 11.48 9.79 591 582 589 737.6666667 587.3333333 0.00160779 -0.341289581 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019185///snRNA-activating protein complex GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III 75641 75641 '1700029I15Rik' mRNA 6 8 8 1.83 2.47 2.6 0.27 1.12 1.13 2.3 0.84 1 4 4 7.333333333 3 0.303524158 -1.296942562 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75642 75642 'Spata25' mRNA 0 1 1 0 0.09 0.09 0 0 0 0.06 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 75646 75646 'Rai14' mRNA 826 767 720 9.21 8.42 8.51 11.81 11.04 11.79 8.713333333 11.54666667 1216 1108 1176 771 1166.666667 5.25E-11 0.586470169 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0030054///cell junction GO:0003779///actin binding GO:0007283///spermatogenesis+++GO:0030154///cell differentiation 75647 75647 'Ssmem1' mRNA 3 7 1 0.21 0.37 0.08 0.04 0 0.06 0.22 0.033333333 1 0 1 3.666666667 0.666666667 0.250717656 -2.450101998 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75656 75656 '1700020A23Rik' mRNA 3 0 1 0.31 0 0.11 0.28 0 0 0.14 0.093333333 3 0 0 1.333333333 1 0.889988966 -0.452268766 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75657 75657 'Speer4a' mRNA 6.26 5.48 5.84 0.25 0.21 0.24 0 0.04 0.04 0.233333333 0.026666667 0 1 1 5.86 0.666666667 0.092044634 -3.004406945 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75659 75659 'Wdr54' mRNA 435 457 370 22.07 22.8 20.03 8.42 8.69 8.56 21.63333333 8.556666667 193 192 188 420.6666667 191 2.24E-15 -1.147413697 GO:0031982///vesicle GO:0042803///protein homodimerization activity GO:0002091///negative regulation of receptor internalization+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0043408///regulation of MAPK cascade 75660 75660 'Lin37' mRNA 483 432 461 30.16 26.76 30.59 24.07 23.32 23.02 29.17 23.47 441 423 412 458.6666667 425.3333333 0.419984914 -0.122054011 04218///Cellular senescence GO:0017053///transcriptional repressor complex+++GO:0031523///Myb complex GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II 75665 75665 'Bicdl1' mRNA 1040 1114 948 18.7 19.66 18.14 12.25 12.18 13.05 18.83333333 12.49333333 786 760 808 1034 784.6666667 9.93E-06 -0.40762454 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0034452///dynactin binding GO:0007399///nervous system development+++GO:0031175///neuron projection development+++GO:0047496///vesicle transport along microtubule+++GO:0055107///Golgi to secretory granule transport 75668 75668 'Rasl10a' mRNA 20 21 15 1.11 1.09 0.84 2.91 3.96 2.77 1.013333333 3.213333333 60 81 55 18.66666667 65.33333333 1.05E-05 1.802554258 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0007165///signal transduction+++GO:0008150///biological_process 75669 75669 'Pik3r4' mRNA 806 863 787 8.83 9.29 9.13 6.89 6.98 7.33 9.083333333 7.066666667 724 717 747 818.6666667 729.3333333 0.091783388 -0.177552844 04136///Autophagy - other+++04140///Autophagy - animal+++04371///Apelin signaling pathway+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis "GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005930///axoneme+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034271///phosphatidylinositol 3-kinase complex, class III, type I+++GO:0034272///phosphatidylinositol 3-kinase complex, class III, type II+++GO:0035032///phosphatidylinositol 3-kinase complex, class III+++GO:0043231///intracellular membrane-bounded organelle+++GO:0071561///nucleus-vacuole junction" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006623///protein targeting to vacuole+++GO:0016236///macroautophagy+++GO:0016310///phosphorylation+++GO:0030242///autophagy of peroxisome+++GO:0032465///regulation of cytokinesis+++GO:0032801///receptor catabolic process+++GO:0042149///cellular response to glucose starvation+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0045324///late endosome to vacuole transport 75671 75671 'Tex22' mRNA 2 4 1 0.11 0.22 0.07 0 0.15 0 0.133333333 0.05 0 3 0 2.333333333 1 0.655860993 -1.194933343 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0008150///biological_process 75677 75677 'Cldn22' mRNA 65 76 80 4.19 4.84 5.47 7.61 6.35 7.61 4.833333333 7.19 135.45 110.19 130.92 73.66666667 125.52 0.004305339 0.74720877 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05130///Pathogenic Escherichia coli infection+++05160///Hepatitis C GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0003674///molecular_function+++GO:0005198///structural molecule activity+++GO:0042802///identical protein binding GO:0007155///cell adhesion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0070830///bicellular tight junction assembly 75678 75678 'Ippk' mRNA 1091.8 1070.73 1114.33 15.28 15.37 15.42 13.74 12.07 15.02 15.35666667 13.61 1188.78 1059.92 1178.76 1092.286667 1142.486667 0.676670148 0.050616868 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035299///inositol pentakisphosphate 2-kinase activity+++GO:0060090///molecular adaptor activity GO:0016310///phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0052746///inositol phosphorylation+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 75686 75686 'Nudt16' mRNA 1029 1156 1062 29.91 33.06 33.37 27.23 26.59 26.65 32.11333333 26.82333333 1010 973 952 1082.333333 978.3333333 0.109385271 -0.15752074 00230///Purine metabolism+++03018///RNA degradation GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm "GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005525///GTP binding+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0030515///snoRNA binding+++GO:0031404///chloride ion binding+++GO:0035870///dITP diphosphatase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0050897///cobalt ion binding+++GO:0097383///dIDP diphosphatase activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides+++GO:1901640///XTP binding+++GO:1901641///ITP binding+++GO:1990003///IDP phosphatase activity+++GO:1990174///phosphodiesterase decapping endonuclease activity" "GO:0006382///adenosine to inosine editing+++GO:0006402///mRNA catabolic process+++GO:0006508///proteolysis+++GO:0008284///positive regulation of cell proliferation+++GO:0009117///nucleotide metabolic process+++GO:0016077///snoRNA catabolic process+++GO:0016311///dephosphorylation+++GO:0035863///dITP catabolic process+++GO:0046709///IDP catabolic process+++GO:0051276///chromosome organization+++GO:0090068///positive regulation of cell cycle process+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1901639///XDP catabolic process+++GO:2000233///negative regulation of rRNA processing+++GO:2000781///positive regulation of double-strand break repair" 75687 75687 'Ripor1' mRNA 1183 1195 994 15.5 15.46 13.34 17.39 17.65 15.93 14.76666667 16.99 1539.95 1540 1390 1124 1489.983333 4.83E-06 0.397728193 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031252///cell leading edge GO:0071889///14-3-3 protein binding GO:0007266///Rho protein signal transduction+++GO:0009267///cellular response to starvation+++GO:0009611///response to wounding+++GO:0030335///positive regulation of cell migration+++GO:0034067///protein localization to Golgi apparatus+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0051683///establishment of Golgi localization+++GO:0090316///positive regulation of intracellular protein transport+++GO:1990869///cellular response to chemokine+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity 75689 75689 'Higd1b' mRNA 168 146 137 16.42 13.64 14.09 7.62 6.02 6.23 14.71666667 6.623333333 86 64 72 150.3333333 74 1.80E-05 -1.034565962 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0097250///mitochondrial respiratory chain supercomplex assembly 75690 75690 'Vsig10l' mRNA 185 201 195 2.77 2.95 3.04 3.11 2.99 3.21 2.92 3.103333333 239 222 238 193.6666667 233 0.181214461 0.254094231 GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 75691 75691 'Anks6' mRNA 61 65 69 0.84 0.96 1.04 0.39 0.54 0.51 0.946666667 0.48 32 42 40 65 38 0.03098886 -0.786591451 GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097543///ciliary inversin compartment GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001701///in utero embryonic development+++GO:0001822///kidney development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development 75692 75692 'Nr2c2ap' mRNA 378.4 369.15 402.28 19.73 19.18 22.31 26.23 29.63 25.99 20.40666667 27.28333333 582.25 638.46 556.05 383.2766667 592.2533333 1.82E-06 0.615028657 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function 75695 75695 'Rilpl1' mRNA 907.38 1032.23 734.85 22.66 25.37 19.46 15.74 15.89 15.96 22.49666667 15.86333333 723.88 715.08 711.76 891.4866667 716.9066667 0.00510959 -0.320719611 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0046983///protein dimerization activity GO:0003382///epithelial cell morphogenesis+++GO:0015031///protein transport+++GO:0060271///cilium assembly+++GO:1901214///regulation of neuron death+++GO:1903445///protein transport from ciliary membrane to plasma membrane 75697 75697 'C2cd4b' mRNA 92 79 20 4.17 3.57 0.97 0.39 1.01 0.9 2.903333333 0.766666667 10 25 22 63.66666667 19 0.001654659 -1.725693335 GO:0002528///regulation of vascular permeability involved in acute inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0030155///regulation of cell adhesion 75698 75698 'Shld2' mRNA 267 228 171 4.72 3.8 3.15 2.03 2.66 1.85 3.89 2.18 142 160 121 222 141 0.002255927 -0.659348843 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035861///site of double-strand break GO:0003674///molecular_function GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0045830///positive regulation of isotype switching+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining 75705 75705 'Eif4b' mRNA 2362 2357 2377 33.15 32.54 35.38 35.03 32.55 34.07 33.69 33.88333333 2873 2608 2706 2365.333333 2729 0.007877221 0.192810045 04150///mTOR signaling pathway+++04151///PI3K-Akt signaling pathway+++05205///Proteoglycans in cancer GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003743///translation initiation factor activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0033592///RNA strand annealing activity+++GO:0034057///RNA strand-exchange activity+++GO:0043024///ribosomal small subunit binding GO:0001731///formation of translation preinitiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0097010///eukaryotic translation initiation factor 4F complex assembly+++GO:1900260///negative regulation of RNA-directed 5'-3' RNA polymerase activity+++GO:1990830///cellular response to leukemia inhibitory factor 75710 75710 'Rbm12' mRNA 833.03 883.54 878.49 12.06 12.57 13.5 9.85 9.62 9.67 12.71 9.713333333 783.37 746.67 744.47 865.02 758.17 0.05282826 -0.203719385 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0043484///regulation of RNA splicing 75712 75712 'Tmem14a' mRNA 294 328 294 15.26 16.53 16.37 16.85 16.31 15.69 16.05333333 16.28333333 373 355 340 305.3333333 356 0.176518375 0.210198433 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0006839///mitochondrial transport+++GO:0043066///negative regulation of apoptotic process+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 75717 75717 'Cul5' mRNA 1042 1136 1105 9.8 10.12 10.43 9.26 9.27 9.34 10.11666667 9.29 1194 1169 1165 1094.333333 1176 0.381544175 0.091211088 04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0090734///site of DNA damage GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0051480///regulation of cytosolic calcium ion concentration 75718 75718 'Vwa5b1' mRNA 0 1 0 0 0.01 0 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function GO:0008150///biological_process 75723 75723 'Amotl1' mRNA 1287 1268 1097 7.46 7.14 6.77 8.66 7.74 8.35 7.123333333 8.25 1710 1510 1617 1217.333333 1612.333333 1.01E-06 0.395279289 04530///Tight junction GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0008180///COP9 signalosome+++GO:0016324///apical plasma membrane+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0001525///angiogenesis+++GO:0003365///establishment of cell polarity involved in ameboidal cell migration+++GO:0016055///Wnt signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0035329///hippo signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration 75725 75725 'Phf14' mRNA 439 393 378 7.49 6.63 6.72 6.19 6.11 6.53 6.946666667 6.276666667 418 402 427 403.3333333 415.6666667 0.863090843 0.032638515 GO:0005634///nucleus+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0042393///histone binding+++GO:0046872///metal ion binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0043972///histone H3-K23 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0048286///lung alveolus development+++GO:0072201///negative regulation of mesenchymal cell proliferation+++GO:2000584///negative regulation of platelet-derived growth factor receptor-alpha signaling pathway+++GO:2000791///negative regulation of mesenchymal cell proliferation involved in lung development 75729 75729 'Fam227a' mRNA 193 176 201 2.68 3.07 3.4 1.07 0.65 1.05 3.05 0.923333333 77 48 78 190 67.66666667 5.38E-10 -1.506784536 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75731 75731 'Idnk' mRNA 524.92 495.42 520.44 15.22 15.1 16.16 20.78 23.08 22.35 15.49333333 22.07 705.96 780.36 755.36 513.5933333 747.2266667 3.25E-06 0.529569628 00030///Pentose phosphate pathway+++01200///Carbon metabolism GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046316///gluconokinase activity GO:0005975///carbohydrate metabolic process+++GO:0016310///phosphorylation+++GO:0046177///D-gluconate catabolic process 75732 75732 'Iqcd' mRNA 374 425 389 11.59 12.62 12.33 1.52 1.99 1.91 12.18 1.806666667 96 110 110 396 105.3333333 1.32E-30 -1.921144557 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0008150///biological_process 75734 75734 'Mff' mRNA 2916 3094 2936 95.24 99.25 101.13 72.31 68.23 70.21 98.54 70.25 2529 2329 2363 2982 2407 1.30E-06 -0.321562608 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005777///peroxisome+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032592///integral component of mitochondrial membrane+++GO:0032991///protein-containing complex+++GO:0045202///synapse GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0051020///GTPase binding GO:0000266///mitochondrial fission+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006626///protein targeting to mitochondrion+++GO:0008053///mitochondrial fusion+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0010821///regulation of mitochondrion organization+++GO:0016559///peroxisome fission+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:0090141///positive regulation of mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900063///regulation of peroxisome organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis 75735 75735 'Pank1' mRNA 548 542 447 3.55 3.46 3.27 2.01 1.76 2.09 3.426666667 1.953333333 328 293 346 512.3333333 322.3333333 2.62E-07 -0.677285089 00770///Pantothenate and CoA biosynthesis+++01240///Biosynthesis of cofactors GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0030118///clathrin coat+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome+++GO:0071944///cell periphery GO:0000166///nucleotide binding+++GO:0004594///pantothenate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:1905502///acetyl-CoA binding GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation 75736 75736 'Bcl2l12' mRNA 229 204 193 13.93 11.86 12.15 14.35 16.68 14.51 12.64666667 15.18 275 314 274 208.6666667 287.6666667 0.008213235 0.45393949 GO:0005634///nucleus GO:0002039///p53 binding GO:0006915///apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1990001///inhibition of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2000773///negative regulation of cellular senescence+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 75739 75739 'Mpp7' mRNA 548.19 525.03 551.97 14.61 15.99 16.49 11.06 10.77 11.4 15.69666667 11.07666667 469.69 424.83 452.69 541.73 449.07 0.02371803 -0.285734937 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0030054///cell junction+++GO:0097025///MPP7-DLG1-LIN7 complex GO:0019904///protein domain specific binding+++GO:0060090///molecular adaptor activity GO:0031334///positive regulation of protein complex assembly+++GO:0070830///bicellular tight junction assembly+++GO:0071896///protein localization to adherens junction 75740 75740 'Egfem1' mRNA 15 16 14 0.35 0.31 0.34 0.42 0.25 0.23 0.333333333 0.3 21 12 11 15 14.66666667 0.95801701 -0.04776121 GO:0005575///cellular_component GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 75744 75744 'Svip' mRNA 1660 1733 1749 29.73 30.54 33.22 19.17 17.75 18.93 31.16333333 18.61666667 1232 1114 1178 1714 1174.666667 1.15E-11 -0.559003785 04141///Protein processing in endoplasmic reticulum GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030868///smooth endoplasmic reticulum membrane+++GO:0031225///anchored component of membrane GO:0043621///protein self-association+++GO:0051117///ATPase binding "GO:0010508///positive regulation of autophagy+++GO:0031333///negative regulation of protein complex assembly+++GO:1903061///positive regulation of protein lipidation+++GO:1903070///negative regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol+++GO:1904240///negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly" 75746 75746 'Morc4' mRNA 138 123 105 1.76 1.54 1.5 4.26 4.09 4.02 1.6 4.123333333 376 356 345 122 359 9.26E-21 1.547876225 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding GO:0008150///biological_process 75747 75747 'Sesn3' mRNA 197 190 94 5.16 4.9 2.61 3.21 2.94 3.76 4.223333333 3.303333333 141 126 160 160.3333333 142.3333333 0.602923333 -0.170389892 04115///p53 signaling pathway+++04211///Longevity regulating pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031932///TORC2 complex+++GO:0061700///GATOR2 complex "GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0070728///leucine binding" GO:0016239///positive regulation of macroautophagy+++GO:0032868///response to insulin+++GO:0034198///cellular response to amino acid starvation+++GO:0038203///TORC2 signaling+++GO:0042149///cellular response to glucose starvation+++GO:0042593///glucose homeostasis+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0051896///regulation of protein kinase B signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0071233///cellular response to leucine+++GO:1901031///regulation of response to reactive oxygen species+++GO:1904262///negative regulation of TORC1 signaling+++GO:1990253///cellular response to leucine starvation 75750 75750 'Slc10a6' mRNA 80 50 72 2.17 1.31 2.03 10.82 10.84 11.7 1.836666667 11.12 464 446 470 67.33333333 460 4.31E-50 2.758081993 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008508///bile acid:sodium symporter activity+++GO:0015293///symporter activity+++GO:0043250///sodium-dependent organic anion transmembrane transporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0015721///bile acid and bile salt transport+++GO:0043251///sodium-dependent organic anion transport+++GO:0055085///transmembrane transport 75751 75751 'Ipo4' mRNA 1681 1731 1731 23.69 24.01 25.83 21.21 20.13 21.24 24.51 20.86 1732 1609 1682 1714.333333 1674.333333 0.636835997 -0.047334318 03013///Nucleocytoplasmic transport GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0031267///small GTPase binding+++GO:0061608///nuclear import signal receptor activity GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006606///protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0042254///ribosome biogenesis 75753 75753 'Klf17' mRNA 1 0 0 0.02 0 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007276///gamete generation 75758 75758 '9130401M01Rik' mRNA 465 479 438 21.47 21.83 21.45 21.95 19.79 24.7 21.58333333 22.14666667 546 480 594 460.6666667 540 0.104877865 0.217927008 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75763 75763 'Dcaf17' mRNA 771.65 818.23 820.98 13.34 13.35 14.26 10.23 11.94 10.93 13.65 11.03333333 733.78 792.28 783.02 803.62 769.6933333 0.575274776 -0.073988468 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 75764 75764 'Slx1b' mRNA 468.62 480.83 450.3 6.88 6.95 7.01 4.61 4.7 4.8 6.946666667 4.703333333 361.22 359.59 364.08 466.5833333 361.63 0.003176615 -0.378144889 03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0033557///Slx1-Slx4 complex GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0017108///5'-flap endonuclease activity+++GO:0046872///metal ion binding GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090656///t-circle formation+++GO:1904431///positive regulation of t-circle formation 75766 75766 'Dcstamp' mRNA 6 0 3 0.17 0 0.13 0.99 1.27 1.31 0.1 1.19 35 50 51 3 45.33333333 3.03E-08 3.907420441 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0002376///immune system process+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030316///osteoclast differentiation+++GO:0034241///positive regulation of macrophage fusion+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0043011///myeloid dendritic cell differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0061025///membrane fusion+++GO:0071353///cellular response to interleukin-4+++GO:0071356///cellular response to tumor necrosis factor+++GO:0072675///osteoclast fusion 75767 75767 'Rab11fip1' mRNA 1742.78 1768.92 1393.05 19.32 20.18 17.75 8.59 9.03 8.37 19.08333333 8.663333333 900.89 891.65 888 1634.916667 893.5133333 9.70E-24 -0.879195786 04144///Endocytosis GO:0005768///endosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome GO:0031267///small GTPase binding GO:0015031///protein transport+++GO:0045055///regulated exocytosis+++GO:0070164///negative regulation of adiponectin secretion 75769 75769 'Plppr5' mRNA 897 949 996 11.02 11.54 12.94 0.63 0.58 0.86 11.83333333 0.69 63 52 77 947.3333333 64 4.01E-133 -3.902554849 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0042577///lipid phosphatase activity GO:0006644///phospholipid metabolic process+++GO:0007165///signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0046839///phospholipid dephosphorylation+++GO:0051491///positive regulation of filopodium assembly 75770 75770 'Brsk2' mRNA 126 97 144 1.55 1.19 1.82 0.51 0.33 0.36 1.52 0.4 49 30 34 122.3333333 37.66666667 4.32E-08 -1.722455722 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0150034///distal axon GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0050321///tau-protein kinase activity+++GO:0051117///ATPase binding GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0006887///exocytosis+++GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0010975///regulation of neuron projection development+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0030182///neuron differentiation+++GO:0031532///actin cytoskeleton reorganization+++GO:0035556///intracellular signal transduction+++GO:0036503///ERAD pathway+++GO:0042149///cellular response to glucose starvation+++GO:0048812///neuron projection morphogenesis+++GO:0050770///regulation of axonogenesis+++GO:0051301///cell division+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0090176///microtubule cytoskeleton organization involved in establishment of planar polarity 75772 75772 'Pnpla5' mRNA 0 3 0 0 0.1 0 0 0 0.04 0.033333333 0.013333333 0 0 2 1 0.666666667 0.892724276 -0.547772576 GO:0005737///cytoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0019433///triglyceride catabolic process+++GO:0055088///lipid homeostasis 75778 75778 'Them4' mRNA 195 232 201 6.67 7.78 7.3 6.83 6.69 6.86 7.25 6.793333333 231 222 228 209.3333333 227 0.627778369 0.106086402 00062///Fatty acid elongation+++04151///PI3K-Akt signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0042995///cell projection GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006915///apoptotic process+++GO:0016032///viral process+++GO:0043491///protein kinase B signaling+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process 75782 75782 'Lca5' mRNA 245 211 213 3.07 2.74 2.67 1.55 1.69 2.15 2.826666667 1.796666667 143 153 183 223 159.6666667 0.013373869 -0.492398654 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0044877///protein-containing complex binding GO:0015031///protein transport+++GO:0042073///intraciliary transport+++GO:0045494///photoreceptor cell maintenance 75784 75784 'Cfap299' mRNA 140 141 139 10.65 10.84 11.37 1.01 0.94 0.89 10.95333333 0.946666667 15 14 13 140 14 2.23E-23 -3.334626784 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 75785 75785 'Klhl24' mRNA 1668.19 1721.15 1626.71 11.07 11.23 11.45 10.39 9.99 9.72 11.25 10.03333333 1835.39 1730.5 1676.11 1672.016667 1747.333333 0.582048336 0.051606529 GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0030424///axon+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0042995///cell projection+++GO:0043204///perikaryon GO:0016567///protein ubiquitination+++GO:0045109///intermediate filament organization+++GO:0051865///protein autoubiquitination+++GO:2000312///regulation of kainate selective glutamate receptor activity 75786 75786 'Ckap5' mRNA 2344.08 2285.94 2154.89 16.84 16.47 16.6 9.07 8.61 7.99 16.63666667 8.556666667 1523.5 1400.46 1309.11 2261.636667 1411.023333 1.37E-20 -0.692405147 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0000930///gamma-tubulin complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0015630///microtubule cytoskeleton+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0035371///microtubule plus-end+++GO:0043204///perikaryon+++GO:0071598///neuronal ribonucleoprotein granule+++GO:0098794///postsynapse" GO:0008017///microtubule binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051010///microtubule plus-end binding+++GO:0061863///microtubule plus end polymerase GO:0002181///cytoplasmic translation+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0007052///mitotic spindle organization+++GO:0007098///centrosome cycle+++GO:0007626///locomotory behavior+++GO:0008542///visual learning+++GO:0010609///mRNA localization resulting in posttranscriptional regulation of gene expression+++GO:0022618///ribonucleoprotein complex assembly+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0032289///central nervous system myelin formation+++GO:0045807///positive regulation of endocytosis+++GO:0046785///microtubule polymerization+++GO:0046959///habituation+++GO:0050658///RNA transport+++GO:0051298///centrosome duplication+++GO:0051301///cell division+++GO:0060079///excitatory postsynaptic potential+++GO:0060291///long-term synaptic potentiation+++GO:0090063///positive regulation of microtubule nucleation+++GO:0097062///dendritic spine maintenance 75788 75788 'Smurf1' mRNA 366 374 350 3.66 3.68 3.71 2.97 2.93 3.01 3.683333333 2.97 342 330 335 363.3333333 335.6666667 0.434112322 -0.125582022 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++04350///TGF-beta signaling pathway GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030424///axon+++GO:0043025///neuronal cell body GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0070411///I-SMAD binding+++GO:0070412///R-SMAD binding GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006611///protein export from nucleus+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0030509///BMP signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0032801///receptor catabolic process+++GO:0034394///protein localization to cell surface+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0061736///engulfment of target by autophagosome+++GO:0061753///substrate localization to autophagosome+++GO:0071211///protein targeting to vacuole involved in autophagy+++GO:1903861///positive regulation of dendrite extension+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 75796 75796 'Cdyl2' mRNA 251 318.6 313.25 1.42 1.64 1.91 1.05 1.28 1.23 1.656666667 1.186666667 244.58 250 277.51 294.2833333 257.3633333 0.282223623 -0.207440769 GO:0005634///nucleus GO:0003714///transcription corepressor activity+++GO:0003824///catalytic activity+++GO:0035064///methylated histone binding "GO:0045892///negative regulation of transcription, DNA-templated" 75799 75799 '4930444P10Rik' mRNA 103 95 84 7.57 6.69 5.95 0.52 1.14 1.02 6.736666667 0.893333333 9 14 15 94 12.66666667 7.05E-14 -2.898786483 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75801 75801 '4930447C04Rik' mRNA 8.31 8.82 7.71 0.17 0.17 0.18 0.22 0.07 0.07 0.173333333 0.12 12.2 4 4.1 8.28 6.766666667 0.863090843 -0.221305198 GO:0000801///central element+++GO:0005694///chromosome GO:0003674///molecular_function GO:0006310///DNA recombination+++GO:0007129///synapsis+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0010705///meiotic DNA double-strand break processing involved in reciprocal meiotic recombination+++GO:0048477///oogenesis+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0051321///meiotic cell cycle 75805 75805 'Nln' mRNA 228 281 283 3 3.61 3.9 7.31 7.95 7.01 3.503333333 7.423333333 628 671 596 264 631.6666667 1.00E-19 1.245320693 04614///Renin-angiotensin system GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070012///oligopeptidase activity GO:0006111///regulation of gluconeogenesis+++GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:1902809///regulation of skeletal muscle fiber differentiation 75812 75812 'Tasp1' mRNA 1013 1065 1038 23.06 24.17 25.22 14.17 14.21 14.09 24.15 14.15666667 694 677 669 1038.666667 680 2.42E-11 -0.623590131 GO:0005737///cytoplasm GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding "GO:0006508///proteolysis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051604///protein maturation" 75820 75820 'Wdr64' mRNA 0 2 0 0 0.03 0 0 0.01 0 0.01 0.003333333 0 1 0 0.666666667 0.333333333 0.863090843 -0.864760308 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75823 75823 'Fam227b' mRNA 0 1 4.31 0 0.04 0.18 0 0 0.04 0.073333333 0.013333333 0 0 1.06 1.77 0.353333333 0.490044418 -2.276798515 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75826 75826 'Senp2' mRNA 1557 1568 1064 18.6 18.42 13.46 8.31 9.28 9.08 16.82666667 8.89 803 874 848 1396.333333 841.6666667 2.87E-10 -0.7330923 03013///Nucleocytoplasmic transport+++04310///Wnt signaling pathway GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0016605///PML body+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016929///SUMO-specific protease activity+++GO:0019904///protein domain specific binding+++GO:0070139///SUMO-specific endopeptidase activity+++GO:0070140///SUMO-specific isopeptidase activity "GO:0001934///positive regulation of protein phosphorylation+++GO:0006508///proteolysis+++GO:0007507///heart development+++GO:0009950///dorsal/ventral axis specification+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0016926///protein desumoylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0031648///protein destabilization+++GO:0032091///negative regulation of protein binding+++GO:0032875///regulation of DNA endoreduplication+++GO:0035562///negative regulation of chromatin binding+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045444///fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051028///mRNA transport+++GO:0051246///regulation of protein metabolic process+++GO:0060707///trophoblast giant cell differentiation+++GO:0060711///labyrinthine layer development+++GO:0060712///spongiotrophoblast layer development+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:2000045///regulation of G1/S transition of mitotic cell cycle" 75828 75828 'Hormad2' mRNA 1 0 0 0.03 0 0 0.06 0.09 0.12 0.01 0.09 2 3 4 0.333333333 3 0.197242891 3.058176959 GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005813///centrosome+++GO:0005829///cytosol GO:0005515///protein binding GO:0051177///meiotic sister chromatid cohesion+++GO:0051321///meiotic cell cycle 75841 75841 'Rnf139' mRNA 572.37 606.29 553.14 7.02 7.35 7.24 7.53 7.19 7.63 7.203333333 7.45 705.66 659.52 693.84 577.2666667 686.34 0.031041931 0.237661034 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0036513///Derlin-1 retrotranslocation complex GO:0002020///protease binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019787///ubiquitin-like protein transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008285///negative regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0017148///negative regulation of translation+++GO:0031648///protein destabilization+++GO:0036503///ERAD pathway+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0070613///regulation of protein processing+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 75847 75847 'Crppa' mRNA 898.35 991.08 831.74 13.33 14.5 13.5 7.68 6.13 7.33 13.77666667 7.046666667 577.59 456.83 529.2 907.0566667 521.2066667 6.59E-14 -0.811214804 00040///Pentose and glucuronate interconversions+++00515///Mannose type O-glycan biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0047349///D-ribitol-5-phosphate cytidylyltransferase activity+++GO:0070567///cytidylyltransferase activity GO:0006486///protein glycosylation+++GO:0007411///axon guidance+++GO:0008299///isoprenoid biosynthetic process+++GO:0035269///protein O-linked mannosylation 75860 75860 'Tex26' mRNA 161 176 153 7.65 7.35 8.58 1.57 0.96 0.92 7.86 1.15 38 27 24 163.3333333 29.66666667 4.11E-19 -2.473231992 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 75861 75861 '4930571K23Rik' mRNA 1 3 1 0.03 0.08 0.03 0 0 0 0.046666667 0 0 0 0 1.666666667 0 0.336674919 -3.174223921 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75869 75869 'Arl5b' mRNA 320 331 281 2.44 2.48 2.26 2.3 1.93 2.47 2.393333333 2.233333333 348 285 361 310.6666667 331.3333333 0.675364409 0.082523271 GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:1903292///protein localization to Golgi membrane 75870 75870 'Tcam1' mRNA 6 8.35 21 0.06 0.09 0.25 0.04 0.07 0.04 0.133333333 0.05 5 7 4 11.78333333 5.333333333 0.251988793 -1.165826073 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 75871 75871 'Zfp821' mRNA 343 364 254 10.54 10.88 8.12 3.72 5.05 5.33 9.846666667 4.7 140 178 189 320.3333333 169 6.93E-07 -0.925474384 GO:0005634///nucleus GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 75886 75886 'Gstt4' mRNA 1 2 0 0.07 0.13 0 0.88 1.44 1.63 0.066666667 1.316666667 16 25 27 1 22.66666667 5.19E-05 4.505082893 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01524///Platinum drug resistance+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation+++05208///Chemical carcinogenesis - reactive oxygen species+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis GO:0005737///cytoplasm GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity GO:0006749///glutathione metabolic process 75894 75894 'Adal' mRNA 965.21 954.06 921.75 10.68 11.2 11.44 7.78 8.35 8.91 11.10666667 8.346666667 762.85 717.44 753.41 947.0066667 744.5666667 1.33E-04 -0.359473661 GO:0005575///cellular_component GO:0004000///adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0019239///deaminase activity+++GO:0046872///metal ion binding GO:0006154///adenosine catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0046103///inosine biosynthetic process 75901 75901 'Dcp1a' mRNA 698 796 850 6.62 7.42 8.54 5.89 5.98 5.57 7.526666667 5.813333333 715 709 655 781.3333333 693 0.148884821 -0.188451851 03018///RNA degradation GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0003729///mRNA binding+++GO:0008047///enzyme activator activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0019894///kinesin binding+++GO:0030234///enzyme regulator activity+++GO:0042802///identical protein binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0031087///deadenylation-independent decapping of nuclear-transcribed mRNA+++GO:0043085///positive regulation of catalytic activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1903608///protein localization to cytoplasmic stress granule" 75905 75905 'Dipk2b' mRNA 32 19 36 0.51 0.29 0.48 0.76 0.54 0.35 0.426666667 0.55 44 41 26 29 37 0.56911885 0.329075677 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function 75906 75906 'Fam184a' mRNA 199 168 158 2.6 2.24 2.29 0.78 0.79 0.83 2.376666667 0.8 70 67 72 175 69.66666667 4.17E-09 -1.338719133 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75909 75909 'Vmp1' mRNA 1848 1892 1951 44.74 46.87 51.66 70.93 68.12 68.73 47.75666667 69.26 4125 3870 3863 1897 3952.666667 4.20E-52 1.045138892 04140///Autophagy - animal GO:0000407///phagophore assembly site+++GO:0000421///autophagosome membrane+++GO:0005730///nucleolus+++GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0007030///Golgi organization+++GO:0007155///cell adhesion+++GO:0007566///embryo implantation+++GO:0016240///autophagosome membrane docking+++GO:0034329///cell junction assembly+++GO:0042953///lipoprotein transport+++GO:0098609///cell-cell adhesion+++GO:0140056///organelle localization by membrane tethering+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:1990456///mitochondrion-endoplasmic reticulum membrane tethering 75914 75914 'Exoc6b' mRNA 1663.34 1760 1638 13.33 13.17 13.09 11.65 11.14 11.11 13.19666667 11.3 1596 1481 1474 1687.113333 1517 0.038637769 -0.165182998 GO:0000145///exocyst+++GO:0016020///membrane GO:0003674///molecular_function GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0090522///vesicle tethering involved in exocytosis 75939 75939 '4930579G24Rik' mRNA 139.09 153.74 135.14 4.03 4.38 4.15 5.77 6.11 5.57 4.186666667 5.816666667 229.28 237.01 214.19 142.6566667 226.8266667 3.86E-04 0.661057956 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 75953 75953 'Samd7' mRNA 1 2 1 0.02 0.03 0.02 0.03 0 0 0.023333333 0.01 2 0 0 1.333333333 0.666666667 0.763915354 -1.02501986 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0042393///histone binding "GO:0010629///negative regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated" 75956 75956 'Srrm2' mRNA 14340 14213 9290 90.4 88.05 57.24 39.63 40.18 44.61 78.56333333 41.47333333 7954 7789 8424 12614.33333 8055.666667 1.39E-04 -0.648938265 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003729///mRNA binding+++GO:0047485///protein N-terminus binding+++GO:0070742///C2H2 zinc finger domain binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 75964 75964 'Trappc8' mRNA 375 382 338 3.48 3.64 3.46 3.82 3.34 3.44 3.526666667 3.533333333 424 359 384 365 389 0.639095842 0.08063767 GO:0000407///phagophore assembly site+++GO:0030008///TRAPP complex+++GO:0031410///cytoplasmic vesicle+++GO:1990072///TRAPPIII protein complex GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0030242///autophagy of peroxisome+++GO:0034497///protein localization to phagophore assembly site 75965 75965 'Zdhhc20' mRNA 971.89 963.87 934.16 11.82 10.62 10.6 13.6 13.38 12.75 11.01333333 13.24333333 1365.17 1247.78 1211.68 956.64 1274.876667 3.52E-06 0.402158701 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0008270///zinc ion binding+++GO:0016409///palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019705///protein-cysteine S-myristoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0046872///metal ion binding" GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0018345///protein palmitoylation 75973 75973 'Ccdc162' mRNA 155 169 133 1.18 1.33 1.05 0.11 0.24 0.14 1.186666667 0.163333333 17 26 15 152.3333333 19.33333333 1.81E-21 -2.984272207 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 75974 75974 'Dock11' mRNA 39 35 23 0.29 0.26 0.18 1.09 1.38 1.48 0.243333333 1.316666667 159 196 208 32.33333333 187.6666667 1.64E-20 2.533377019 GO:0005575///cellular_component GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031267///small GTPase binding GO:0001782///B cell homeostasis+++GO:0002315///marginal zone B cell differentiation+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051491///positive regulation of filopodium assembly 75985 75985 'Rab30' mRNA 813.3 855.94 800.2 8.18 7.97 7.33 7.17 6.69 5.44 7.826666667 6.433333333 700.91 676.54 582.76 823.1466667 653.4033333 0.001495901 -0.34588255 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0031985///Golgi cisterna+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0007030///Golgi organization+++GO:0032482///Rab protein signal transduction 75986 75986 'Agmat' mRNA 4 4 1 0.18 0.18 0.05 0.19 0 0.2 0.136666667 0.13 5 0 5 3 3.333333333 0.940291259 0.150091457 00330///Arginine and proline metabolism GO:0005739///mitochondrion GO:0008783///agmatinase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding "GO:0008295///spermidine biosynthetic process+++GO:0009446///putrescine biosynthetic process+++GO:0033388///putrescine biosynthetic process from arginine+++GO:0033389///putrescine biosynthetic process from arginine, using agmatinase" 75991 75991 'Slain2' mRNA 686 744 420 8.09 8.63 5.59 4.53 3.8 4.94 7.436666667 4.423333333 419 344 446 616.6666667 403 3.30E-04 -0.615310494 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0035371///microtubule plus-end GO:0003674///molecular_function GO:0007020///microtubule nucleation+++GO:0031113///regulation of microtubule polymerization+++GO:0031116///positive regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization 76002 76002 'Ms4a18' mRNA 2 0 1 0.09 0 0.05 0.04 0.27 0.2 0.046666667 0.17 1 7 5 1 4.333333333 0.266916012 2.11211787 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76007 76007 'Zmym2' mRNA 1337.31 1304.38 1226.12 12.34 11.77 11.7 8.23 7.44 9.33 11.93666667 8.333333333 1023.84 898.16 1045.92 1289.27 989.3066667 9.23E-06 -0.394365554 GO:0005634///nucleus+++GO:0016605///PML body GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding 76014 76014 'Zc3h18' mRNA 826 847 795 11.83 11.9 12.06 11.19 10.4 10.34 11.93 10.64333333 905 822 812 822.6666667 846.3333333 0.832852729 0.02886722 GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0032991///protein-containing complex+++GO:1990904///ribonucleoprotein complex "GO:0030674///protein binding, bridging+++GO:0046872///metal ion binding+++GO:0140262///mRNA cap binding complex binding" GO:0050779///RNA destabilization 76022 76022 'Gon4l' mRNA 2032.05 2142.76 1874.28 14.14 14.64 13.82 11.77 10.1 11.83 14.2 11.23333333 1949.96 1635.43 1898.52 2016.363333 1827.97 0.072236635 -0.152909639 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0031011///Ino80 complex GO:0003712///transcription coregulator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding "GO:0006355///regulation of transcription, DNA-templated+++GO:0030183///B cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 76025 76025 'Cant1' mRNA 1978 1896 1902 30.64 29.27 31.41 34.63 30.36 31.18 30.44 32.05666667 2404 2118 2182 1925.333333 2234.666667 0.009109329 0.201613088 00230///Purine metabolism+++00240///Pyrimidine metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0000166///nucleotide binding+++GO:0004382///guanosine-diphosphatase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0043262///adenosine-diphosphatase activity+++GO:0045134///uridine-diphosphatase activity+++GO:0046872///metal ion binding+++GO:0102485///dATP phosphohydrolase activity+++GO:0102486///dCTP phosphohydrolase activity+++GO:0102487///dUTP phosphohydrolase activity+++GO:0102488///dTTP phosphohydrolase activity+++GO:0102489///GTP phosphohydrolase activity+++GO:0102490///8-oxo-dGTP phosphohydrolase activity+++GO:0102491///dGTP phosphohydrolase activity GO:0009124///nucleoside monophosphate biosynthetic process+++GO:0009133///nucleoside diphosphate biosynthetic process+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0009191///ribonucleoside diphosphate catabolic process+++GO:0030166///proteoglycan biosynthetic process 76041 76041 'Ccdc125' mRNA 100.62 99.62 123.6 1.94 1.71 2.65 3.24 2.63 3.72 2.1 3.196666667 171.72 158 205.21 107.9466667 178.31 0.002078598 0.713099706 GO:0005737///cytoplasm GO:0042802///identical protein binding GO:0035024///negative regulation of Rho protein signal transduction+++GO:0090630///activation of GTPase activity+++GO:2000145///regulation of cell motility+++GO:2000146///negative regulation of cell motility 76044 76044 'Ncapg2' mRNA 118 134 117 0.95 1.08 1.04 3.51 3 2.85 1.023333333 3.12 502 421 393 123 438.6666667 2.27E-29 1.822186196 GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016607///nuclear speck GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0030293///transmembrane receptor protein tyrosine kinase inhibitor activity+++GO:0035033///histone deacetylase regulator activity+++GO:0035064///methylated histone binding+++GO:0043425///bHLH transcription factor binding GO:0000070///mitotic sister chromatid segregation+++GO:0001833///inner cell mass cell proliferation+++GO:0006366///transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0030218///erythrocyte differentiation+++GO:0030261///chromosome condensation+++GO:0031063///regulation of histone deacetylation+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:2000272///negative regulation of signaling receptor activity 76051 76051 'Ganc' mRNA 724.26 743.86 631.28 8.04 8.12 7.44 5.26 5.55 5.22 7.866666667 5.343333333 545.7 561.96 524.26 699.8 543.9733333 6.56E-04 -0.373057872 00052///Galactose metabolism+++00500///Starch and sucrose metabolism GO:0005575///cellular_component "GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004558///alpha-1,4-glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0032450///maltose alpha-glucosidase activity+++GO:0090599///alpha-glucosidase activity" GO:0000023///maltose metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006491///N-glycan processing+++GO:0008152///metabolic process 76055 76055 'Oga' mRNA 1443 1550 1364 16.47 17.52 16.63 13.87 13.41 13.89 16.87333333 13.72333333 1383 1322 1348 1452.333333 1351 0.183014001 -0.114818087 04931///Insulin resistance GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016021///integral component of membrane "GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0016231///beta-N-acetylglucosaminidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0102166///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity+++GO:0102167///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity+++GO:0102571///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity" GO:0006044///N-acetylglucosamine metabolic process+++GO:0006517///protein deglycosylation+++GO:0006612///protein targeting to membrane+++GO:0008152///metabolic process+++GO:0009100///glycoprotein metabolic process+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0010616///negative regulation of cardiac muscle adaptation+++GO:0016573///histone acetylation+++GO:0031343///positive regulation of cell killing+++GO:0032024///positive regulation of insulin secretion+++GO:0043243///positive regulation of protein complex disassembly+++GO:0045862///positive regulation of proteolysis+++GO:0046060///dATP metabolic process+++GO:0046326///positive regulation of glucose import+++GO:0051054///positive regulation of DNA metabolic process+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0051928///positive regulation of calcium ion transport+++GO:0060051///negative regulation of protein glycosylation+++GO:0060124///positive regulation of growth hormone secretion+++GO:0070265///necrotic cell death 76071 76071 'Jakmip1' mRNA 193 160 199 3.64 2.95 4.03 0.56 0.33 0.16 3.54 0.35 31 28 11 184 23.33333333 1.10E-21 -2.997124901 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0008017///microtubule binding+++GO:0019894///kinesin binding+++GO:0019900///kinase binding+++GO:0050811///GABA receptor binding GO:0015031///protein transport+++GO:0021756///striatum development+++GO:0050890///cognition 76072 76072 'Rnf183' mRNA 2 1 2 0.09 0.05 0.1 0.76 1.02 0.78 0.08 0.853333333 19 25 19 1.666666667 21 1.34E-04 3.643290834 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0033106///cis-Golgi network membrane GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0051865///protein autoubiquitination+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 76073 76073 'Pcgf5' mRNA 607 632 449 4.99 5.11 3.93 3.43 3.44 3.32 4.676666667 3.396666667 480 469 450 562.6666667 466.3333333 0.045175479 -0.27656732 04550///Signaling pathways regulating pluripotency of stem cells GO:0000805///X chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060819///inactivation of X chromosome by genetic imprinting 76074 76074 'Gbp8' mRNA 117.65 91.79 83.1 2.24 1.81 1.78 3.51 3.42 3.48 1.943333333 3.47 194.31 183.64 187.35 97.51333333 188.4333333 1.22E-05 0.945505827 GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0042832///defense response to protozoan+++GO:0050830///defense response to Gram-positive bacterium+++GO:0071346///cellular response to interferon-gamma 76080 76080 'Ttpal' mRNA 461 550 526 5.49 6.38 6.67 10.03 9.4 9.18 6.18 9.536666667 973 888 865 512.3333333 908.6666667 1.27E-13 0.81311636 GO:1902936///phosphatidylinositol bisphosphate binding GO:0008150///biological_process 76088 76088 'Dock8' mRNA 420 456 349 5.51 5.92 4.95 13.42 15.59 14.75 5.46 14.58666667 1159 1290 1231 408.3333333 1226.666667 1.43E-50 1.580308268 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031252///cell leading edge+++GO:0031256///leading edge membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0036336///dendritic cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061485///memory T cell proliferation+++GO:0070233///negative regulation of T cell apoptotic process+++GO:1903905///positive regulation of establishment of T cell polarity+++GO:1990869///cellular response to chemokine+++GO:2000406///positive regulation of T cell migration 76089 76089 'Rapgef2' mRNA 881.15 871.52 885.51 3.81 3.82 4.26 3.12 3.54 3.45 3.963333333 3.37 781.85 750.92 820.18 879.3933333 784.3166667 0.094871862 -0.178415938 04010///MAPK signaling pathway+++04015///Rap1 signaling pathway+++04530///Tight junction GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030139///endocytic vesicle+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding+++GO:0030552///cAMP binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0050699///WW domain binding+++GO:0070300///phosphatidic acid binding GO:0001568///blood vessel development+++GO:0001764///neuron migration+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0007264///small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0019933///cAMP-mediated signaling+++GO:0021591///ventricular system development+++GO:0021884///forebrain neuron development+++GO:0030033///microvillus assembly+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0032486///Rap protein signal transduction+++GO:0038180///nerve growth factor signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0043547///positive regulation of GTPase activity+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0045860///positive regulation of protein kinase activity+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0048167///regulation of synaptic plasticity+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0061028///establishment of endothelial barrier+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071320///cellular response to cAMP+++GO:0071321///cellular response to cGMP+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0090557///establishment of endothelial intestinal barrier+++GO:1901888///regulation of cell junction assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity+++GO:2000670///positive regulation of dendritic cell apoptotic process+++GO:2001214///positive regulation of vasculogenesis+++GO:2001224///positive regulation of neuron migration 76108 76108 'Rap2a' mRNA 177 234 187 2.28 2.97 2.56 5.92 5.63 6.34 2.603333333 5.963333333 528 491 548 199.3333333 522.3333333 7.62E-22 1.37975291 GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007165///signal transduction+++GO:0030033///microvillus assembly+++GO:0030336///negative regulation of cell migration+++GO:0031532///actin cytoskeleton reorganization+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032486///Rap protein signal transduction+++GO:0034613///cellular protein localization+++GO:0035690///cellular response to drug+++GO:0045184///establishment of protein localization+++GO:0046328///regulation of JNK cascade+++GO:0048814///regulation of dendrite morphogenesis+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0072659///protein localization to plasma membrane 76113 76113 'Lpo' mRNA 373 325 333 7.44 6.36 7.05 6.3 6.59 6.27 6.95 6.386666667 363 372 350 343.6666667 361.6666667 0.74639348 0.062094503 04970///Salivary secretion+++05208///Chemical carcinogenesis - reactive oxygen species GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane GO:0004601///peroxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0036393///thiocyanate peroxidase activity GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0006979///response to oxidative stress+++GO:0018969///thiocyanate metabolic process+++GO:0042742///defense response to bacterium+++GO:0098869///cellular oxidant detoxification 76117 76117 'Arhgap15' mRNA 1189.33 1176.92 1072.43 33.3 32.43 31.8 22.91 20.3 21.35 32.51 21.52 955.95 826.22 865.3 1146.226667 882.49 1.42E-05 -0.388809171 GO:0005737///cytoplasm+++GO:0016020///membrane GO:0005096///GTPase activator activity GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 76123 76123 'Gpsm2' mRNA 878.24 1009.61 770.17 13.78 15.53 12.78 4.94 5.58 5.92 14.03 5.48 359.19 395.99 416.04 886.0066667 390.4066667 2.97E-24 -1.189764902 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell+++GO:0097431///mitotic spindle pole+++GO:0097575///lateral cell cortex+++GO:0099738///cell cortex region GO:0000166///nucleotide binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0030695///GTPase regulator activity+++GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0070840///dynein complex binding GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0031291///Ran protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0051301///cell division+++GO:0051661///maintenance of centrosome location+++GO:0060236///regulation of mitotic spindle organization+++GO:0060487///lung epithelial cell differentiation+++GO:1904778///positive regulation of protein localization to cell cortex+++GO:1905832///positive regulation of spindle assembly 76130 76130 'Las1l' mRNA 1524 1577.58 1398 32.39 33 31.51 26.57 26.67 24.26 32.3 25.83333333 1439.01 1410 1271 1499.86 1373.336667 0.123725948 -0.137322777 "GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030687///preribosome, large subunit precursor+++GO:0071339///MLL1 complex+++GO:0090730///Las1 complex" GO:0004519///endonuclease activity GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA+++GO:0006364///rRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 76131 76131 'Depdc1a' mRNA 0 1 1 0 0.02 0.02 1.42 1.35 1.14 0.013333333 1.303333333 87 74 60 0.666666667 73.66666667 1.62E-09 6.774356716 GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex GO:0005096///GTPase activator activity "GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050790///regulation of catalytic activity" 76132 76132 'Faxc' mRNA 165 194 139 0.94 1.09 0.83 0.7 0.55 0.69 0.953333333 0.646666667 140 106 135 166 127 0.091995241 -0.394754851 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76137 76137 'Mcur1' mRNA 637 677 325 7.86 8.22 4.25 7.7 12.59 10.88 6.776666667 10.39 718 1147 983 546.3333333 949.3333333 0.040750904 0.805799599 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0003674///molecular_function GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0070509///calcium ion import 76138 76138 'Ccdc138' mRNA 306 316 315 6.22 6.28 6.92 2.2 2.13 2.09 6.473333333 2.14 123 118 118 312.3333333 119.6666667 2.20E-16 -1.396976979 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76142 76142 'Ppp1r14c' mRNA 205.35 162.57 176.59 3.1 2.47 2.63 3.39 3.27 3.61 2.733333333 3.423333333 232.22 214.09 224.63 181.5033333 223.6466667 0.145783098 0.290579694 GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity GO:0007165///signal transduction+++GO:0042325///regulation of phosphorylation+++GO:0043086///negative regulation of catalytic activity 76156 76156 'Fam131b' mRNA 10.76 3.28 1.15 0.14 0.04 0.02 0.02 0 0.01 0.066666667 0.01 2 0 1 5.063333333 1 0.240858302 -2.223313624 GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003674///molecular_function 76157 76157 'Slc35d3' mRNA 11 1 4 0.23 0.01 0.09 0.09 0.11 0.21 0.11 0.136666667 5 6 12 5.333333333 7.666666667 0.715841403 0.516737517 GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005461///UDP-glucuronic acid transmembrane transporter activity+++GO:0005462///UDP-N-acetylglucosamine transmembrane transporter activity+++GO:0005463///UDP-N-acetylgalactosamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015297///antiporter activity GO:0008643///carbohydrate transport+++GO:0015787///UDP-glucuronic acid transmembrane transport+++GO:0015789///UDP-N-acetylgalactosamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0097009///energy homeostasis+++GO:1990569///UDP-N-acetylglucosamine transmembrane transport 76161 76161 'Lamp5' mRNA 10 7 9 0.32 0.16 0.27 0.28 0.18 0.32 0.25 0.26 11 8 12 8.666666667 10.33333333 0.830659375 0.237881828 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0032584///growth cone membrane+++GO:0032590///dendrite membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0003674///molecular_function GO:0072594///establishment of protein localization to organelle 76166 76166 'Cplane2' mRNA 66 43 50 4.49 2.9 3.61 1.25 1.04 0.98 3.666666667 1.09 21 17 16 53 18 3.52E-04 -1.571459032 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0030030///cell projection organization+++GO:0031338///regulation of vesicle fusion+++GO:0034613///cellular protein localization+++GO:0060271///cilium assembly 76167 76167 'Snrnp35' mRNA 257.62 268.78 254.42 8.45 8.69 9.88 16.95 13.96 14.38 9.006666667 15.09666667 441.12 380.92 342.24 260.2733333 388.0933333 1.85E-04 0.565085368 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005730///nucleolus GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0017069///snRNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 76178 76178 'Coa5' mRNA 2017 2190 2147 28.24 30.17 31.89 33.69 28.17 30.16 30.1 30.67333333 2769 2262 2401 2118 2477.333333 0.015580905 0.211347052 04714///Thermogenesis GO:0005739///mitochondrion GO:0003674///molecular_function GO:0033617///mitochondrial respiratory chain complex IV assembly 76179 76179 'Usp31' mRNA 387 401 272 2.04 1.98 1.45 1.37 1.24 1.26 1.823333333 1.29 303 277 280 353.3333333 286.6666667 0.071699818 -0.306952356 GO:0005634///nucleus+++GO:0016021///integral component of membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination 76183 76183 'Celf6' mRNA 58 70 67 0.92 1.18 1.15 0.11 0.09 0.04 1.083333333 0.08 7 6 4 65 5.666666667 8.49E-12 -3.533967478 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0071625///vocalization behavior+++GO:0099153///synaptic transmission, serotonergic" 76184 76184 'Abca6' mRNA 164.13 214.99 157.07 1.8 2.59 1.69 1.71 1.73 1.67 2.026666667 1.703333333 143.99 124.7 114.27 178.73 127.6533333 0.025172504 -0.498781716 02010///ABC transporters GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0000166///nucleotide binding+++GO:0005319///lipid transporter activity+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0006869///lipid transport+++GO:0055085///transmembrane transport 76187 76187 'Adhfe1' mRNA 326 359 330 5.51 5.94 5.89 5.38 3.96 4.37 5.78 4.57 366 263 286 338.3333333 305 0.374118887 -0.163810237 GO:0005739///mitochondrion GO:0004022///alcohol dehydrogenase (NAD) activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0047988///hydroxyacid-oxoacid transhydrogenase activity GO:0006539///glutamate catabolic process via 2-oxoglutarate 76192 76192 'Abhd12' mRNA 4921 4838 4126 163.34 158.76 146.62 131.5 148.63 145.43 156.24 141.8533333 4429 4965 4801 4628.333333 4731.666667 0.809860504 0.024535332 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0032839///dendrite cytoplasm GO:0004620///phospholipase activity+++GO:0004622///lysophospholipase activity+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047372///acylglycerol lipase activity GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process+++GO:0006660///phosphatidylserine catabolic process+++GO:0007628///adult walking behavior+++GO:0009395///phospholipid catabolic process+++GO:0010996///response to auditory stimulus+++GO:0046464///acylglycerol catabolic process+++GO:0046475///glycerophospholipid catabolic process+++GO:0050727///regulation of inflammatory response+++GO:0052651///monoacylglycerol catabolic process 76199 76199 'Med13l' mRNA 989 1016 855 5.59 5.64 5.13 4.38 3.71 4.28 5.453333333 4.123333333 894 737 847 953.3333333 826 0.040007429 -0.217118903 04919///Thyroid hormone signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II 76205 76205 'Stard3nl' mRNA 1232.82 1335.66 1169.33 49.06 53.5 47.69 63.89 75.9 73.19 50.08333333 70.99333333 1900.35 2176.76 2098.09 1245.936667 2058.4 2.66E-17 0.716008013 GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0044232///organelle membrane contact site GO:0015485///cholesterol binding+++GO:0042803///protein homodimerization activity GO:0099044///vesicle tethering to endoplasmic reticulum 76206 76206 'Gpr165' mRNA 17 17 11 0.29 0.29 0.2 0.03 0 0 0.26 0.01 2 0 0 15 0.666666667 0.001151689 -4.502623522 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 76217 76217 'Jakmip2' mRNA 31 34 25 0.45 0.46 0.34 0.05 0.01 0.04 0.416666667 0.033333333 5 1 3 30 3 1.03E-05 -3.333369544 GO:0005794///Golgi apparatus GO:0003674///molecular_function+++GO:0008017///microtubule binding+++GO:0019900///kinase binding GO:0008150///biological_process 76219 76219 'Arxes1' mRNA 334.42 289.51 336.89 12.41 10.6 13.27 5.77 5.72 6.03 12.09333333 5.84 178.6 172.8 180.51 320.2733333 177.3033333 1.97E-07 -0.870248432 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006465///signal peptide processing+++GO:0045047///protein targeting to ER+++GO:0045444///fat cell differentiation 76223 76223 'Agbl3' mRNA 236.6 228.74 208.23 5.82 5.76 5.39 2.43 2.62 2.59 5.656666667 2.546666667 109.2 101.05 133.01 224.5233333 114.42 7.59E-07 -0.980437396 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0035610///protein side chain deglutamylation 76229 76229 'Vmn2r29' mRNA 22.02 23.85 22.47 0.48 0.51 0.52 0.37 0.31 0.22 0.503333333 0.3 19.48 15.79 11.48 22.78 15.58333333 0.372975094 -0.588513389 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 76233 76233 'Dnttip1' mRNA 62 66 55 3.04 3.19 2.86 4.14 3.76 4.59 3.03 4.163333333 97 86 104 61 95.66666667 0.028316032 0.639419466 GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0008047///enzyme activator activity+++GO:0031491///nucleosome binding+++GO:0042803///protein homodimerization activity GO:0050790///regulation of catalytic activity 76237 76237 '6430628N08Rik' mRNA 13 13 6 0.47 0.47 0.23 0.1 0.03 0.07 0.39 0.066666667 3 1 2 10.66666667 2 0.034367229 -2.41756957 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76238 76238 'Grhpr' mRNA 736 633 596 34.85 29.59 29.95 27.76 26.85 26.53 31.46333333 27.04666667 673 635 622 655 643.3333333 0.817765339 -0.036323676 "00260///Glycine, serine and threonine metabolism+++00620///Pyruvate metabolism+++00630///Glyoxylate and dicarboxylate metabolism" GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1902494///catalytic complex "GO:0008465///glycerate dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016618///hydroxypyruvate reductase activity+++GO:0030267///glyoxylate reductase (NADP) activity+++GO:0031406///carboxylic acid binding+++GO:0042803///protein homodimerization activity+++GO:0050661///NADP binding+++GO:0051287///NAD binding+++GO:0070402///NADPH binding" GO:0007588///excretion+++GO:0043648///dicarboxylic acid metabolic process+++GO:0046487///glyoxylate metabolic process 76246 76246 'Rtf1' mRNA 331 302 236 3.7 3.32 2.81 2.5 3.05 2.75 3.276666667 2.766666667 255 303 271 289.6666667 276.3333333 0.748435514 -0.073128924 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016593///Cdc73/Paf1 complex GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001711///endodermal cell fate commitment+++GO:0001832///blastocyst growth+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016055///Wnt signaling pathway+++GO:0019827///stem cell population maintenance+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation 76251 76251 'Ercc6l2' mRNA 574 627 614 4.9 5.29 5.94 3.86 3.39 3.9 5.376666667 3.716666667 481 436 460 605 459 5.35E-04 -0.411780881 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0034614///cellular response to reactive oxygen species+++GO:0036297///interstrand cross-link repair 76252 76252 'Atp6v0e2' mRNA 3350 3424 3080 104.97 105.84 102.48 63.74 66.49 68.76 104.43 66.33 2337 2379 2439 3284.666667 2385 6.71E-14 -0.471688961 00190///Oxidative phosphorylation+++04145///Phagosome+++04721///Synaptic vesicle cycle+++04966///Collecting duct acid secretion+++05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis "GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033179///proton-transporting V-type ATPase, V0 domain" "GO:0015078///proton transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism" GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport 76257 76257 'Slc38a3' mRNA 579 619 578 13.05 13.76 13.83 8.26 7.95 9.37 13.54666667 8.526666667 419 395 461 592 425 5.03E-05 -0.489701632 04724///Glutamatergic synapse+++04727///GABAergic synapse+++04964///Proximal tubule bicarbonate reclamation GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane "GO:0004060///arylamine N-acetyltransferase activity+++GO:0005290///L-histidine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015182///L-asparagine transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0003333///amino acid transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006865///amino acid transport+++GO:0006867///asparagine transport+++GO:0006868///glutamine transport+++GO:0007420///brain development+++GO:0007565///female pregnancy+++GO:0015808///L-alanine transport+++GO:0015817///histidine transport+++GO:0051365///cellular response to potassium ion starvation+++GO:0061402///positive regulation of transcription from RNA polymerase II promoter in response to acidic pH+++GO:0089709///L-histidine transmembrane transport+++GO:2000487///positive regulation of glutamine transport 76260 76260 'Ttc8' mRNA 932 990 845 23 24.06 22.12 11.01 10.57 12.79 23.06 11.45666667 513 481 577 922.3333333 523.6666667 4.74E-15 -0.826155797 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0034464///BBSome+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097730///non-motile cilium GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005515///protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0001736///establishment of planar polarity+++GO:0007411///axon guidance+++GO:0007608///sensory perception of smell+++GO:0015031///protein transport+++GO:0021772///olfactory bulb development+++GO:0030030///cell projection organization+++GO:0032880///regulation of protein localization+++GO:0034260///negative regulation of GTPase activity+++GO:0035264///multicellular organism growth+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0045444///fat cell differentiation+++GO:0048560///establishment of anatomical structure orientation+++GO:0051492///regulation of stress fiber assembly+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060219///camera-type eye photoreceptor cell differentiation+++GO:0060271///cilium assembly+++GO:0061326///renal tubule development+++GO:0072659///protein localization to plasma membrane+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:1905515///non-motile cilium assembly 76261 76261 '0610040J01Rik' mRNA 669 650 719 20.58 19.63 23.4 12.2 9.26 10.6 21.20333333 10.68666667 459 342 382 679.3333333 394.3333333 1.14E-09 -0.801830485 GO:0005654///nucleoplasm+++GO:0030054///cell junction GO:0003674///molecular_function GO:0008150///biological_process 76263 76263 'Gstk1' mRNA 1155 1142 979 80.9 79.16 72.76 49.45 52.25 53.27 77.60666667 51.65666667 809 833 842 1092 828 9.79E-06 -0.407892629 00480///Glutathione metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04146///Peroxisome+++05204///Chemical carcinogenesis - DNA adducts GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005777///peroxisome GO:0004364///glutathione transferase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016740///transferase activity GO:0006749///glutathione metabolic process+++GO:0030855///epithelial cell differentiation+++GO:0098869///cellular oxidant detoxification 76265 76265 'Tsen54' mRNA 453 506 367 11.95 13.19 11.08 9.96 9.26 9.93 12.07333333 9.716666667 401 369 386 442 385.3333333 0.173061622 -0.204981103 GO:0000214///tRNA-intron endonuclease complex+++GO:0005634///nucleus+++GO:0005730///nucleolus "GO:0000379///tRNA-type intron splice site recognition and cleavage+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing" 76267 76267 'Fads1' mRNA 4514 4581 4488 70.95 70.87 74.85 74.4 70.3 71.74 72.22333333 72.14666667 5445 5026 5085 4527.666667 5185.333333 0.002736207 0.182716382 01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0016213///linoleoyl-CoA desaturase activity+++GO:0016491///oxidoreductase activity+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0007568///aging+++GO:0007584///response to nutrient+++GO:0009267///cellular response to starvation+++GO:0009744///response to sucrose+++GO:0010033///response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0019369///arachidonic acid metabolic process+++GO:0032868///response to insulin+++GO:0033189///response to vitamin A+++GO:0035900///response to isolation stress+++GO:0042759///long-chain fatty acid biosynthetic process 76273 76273 'Ndfip2' mRNA 1420 1415 976 32.8 31.96 23.87 15.74 17.69 17.3 29.54333333 16.91 788 871 839 1270.333333 832.6666667 1.92E-07 -0.612361725 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032585///multivesicular body membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0050699///WW domain binding GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007034///vacuolar transport+++GO:0010629///negative regulation of gene expression+++GO:0030001///metal ion transport+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032410///negative regulation of transporter activity+++GO:0051224///negative regulation of protein transport 76281 76281 'Tax1bp3' mRNA 1946 2070 1949 81.88 85.93 87 135.55 149.08 141.54 84.93666667 142.0566667 3700 3970 3737 1988.333333 3802.333333 1.22E-41 0.924435296 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding GO:0007266///Rho protein signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0090630///activation of GTPase activity+++GO:2000009///negative regulation of protein localization to cell surface 76282 76282 'Gpt' mRNA 124 118 117 4 3.75 4 2.53 2.53 3.1 3.916666667 2.72 90 88 107 119.6666667 95 0.196872634 -0.34453516 "00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01200///Carbon metabolism+++01210///2-Oxocarboxylic acid metabolism+++01230///Biosynthesis of amino acids" GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0003824///catalytic activity+++GO:0004021///L-alanine:2-oxoglutarate aminotransferase activity+++GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding GO:0009058///biosynthetic process+++GO:0032869///cellular response to insulin stimulus+++GO:0042594///response to starvation+++GO:0042853///L-alanine catabolic process+++GO:0045722///positive regulation of gluconeogenesis 76293 76293 'Mfap4' mRNA 134 149 113 5.15 5.64 4.6 13.15 15.85 18.1 5.13 15.7 392 462 523 132 459 3.96E-26 1.791996966 GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0071953///elastic fiber GO:0003823///antigen binding+++GO:0005102///signaling receptor binding+++GO:0005201///extracellular matrix structural constituent+++GO:0097367///carbohydrate derivative binding "GO:0001867///complement activation, lectin pathway+++GO:0007155///cell adhesion+++GO:0009650///UV protection+++GO:0010712///regulation of collagen metabolic process+++GO:0048251///elastic fiber assembly+++GO:0071493///cellular response to UV-B+++GO:0097435///supramolecular fiber organization" 76294 76294 'Asb5' mRNA 1 1 9 0.04 0.01 0.27 0.27 0.12 0.17 0.106666667 0.186666667 14 3 9 3.666666667 8.666666667 0.385016041 1.17623404 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0045732///positive regulation of protein catabolic process 76295 76295 'Atp11b' mRNA 823 822 787 8.94 8.77 9.08 9.91 9.2 8.74 8.93 9.283333333 1051 954 893 810.6666667 966 0.017118929 0.240485532 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0015917///aminophospholipid transport+++GO:0034204///lipid translocation+++GO:0045332///phospholipid translocation 76299 76299 'Erp44' mRNA 1393 1470 1408 14.1 14.63 15.12 21.84 21.49 21.17 14.61666667 21.5 2484 2387 2331 1423.666667 2400.666667 8.23E-26 0.741600625 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0009986///cell surface GO:0003756///protein disulfide isomerase activity+++GO:0005515///protein binding GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0009100///glycoprotein metabolic process+++GO:0034976///response to endoplasmic reticulum stress 76302 76302 'Pcnp' mRNA 2948 3190 3109 72.22 77.13 81.21 79.46 72.93 73.68 76.85333333 75.35666667 3712 3343 3329 3082.333333 3461.333333 0.040965812 0.153619413 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 76303 76303 'Osbp' mRNA 439 477 497 4.95 5.32 5.94 6.75 6.06 6.8 5.403333333 6.536666667 682 593 671 471 648.6666667 2.85E-04 0.446888411 GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0019904///protein domain specific binding+++GO:0032934///sterol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120015///intermembrane sterol transfer activity GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0032367///intracellular cholesterol transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0120009///intermembrane lipid transfer+++GO:1904411///positive regulation of secretory granule organization 76306 76306 'Slc18b1' mRNA 449.41 430.28 312.47 9.25 8.67 6.73 5.91 6.08 5.84 8.216666667 5.943333333 338.28 331.69 320.53 397.3866667 330.1666667 0.089392524 -0.273694873 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0055085///transmembrane transport 76308 76308 'Rab1b' mRNA 4744 4932 4684 148.66 152.3 155.71 170.88 177.05 173.08 152.2233333 173.67 6268 6339 6144 4786.666667 6250.333333 4.04E-11 0.373384593 05134///Legionellosis GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0034045///phagophore assembly site membrane+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity GO:0000045///autophagosome assembly+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0019068///virion assembly+++GO:1903020///positive regulation of glycoprotein metabolic process+++GO:2000785///regulation of autophagosome assembly 76332 76332 'Cog2' mRNA 790 829 781 15.43 15.93 16.18 14.02 15.14 13.39 15.84666667 14.18333333 826 871 764 800 820.3333333 0.863090843 0.025058958 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0044877///protein-containing complex binding GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport 76338 76338 'Rab2b' mRNA 761 787 795 15.24 15.52 16.9 13.63 11.6 11.51 15.88666667 12.24666667 782 651 640 781 691 0.112000902 -0.191353562 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0045921///positive regulation of exocytosis 76355 76355 'Tgds' mRNA 340 302 333 8.44 7.38 8.77 9.3 10.41 8.83 8.196666667 9.513333333 431 471 396 325 432.6666667 0.007030055 0.399981322 00523///Polyketide sugar unit biosynthesis+++01250///Biosynthesis of nucleotide sugars GO:0005575///cellular_component "GO:0008460///dTDP-glucose 4,6-dehydratase activity+++GO:0016829///lyase activity" GO:0008150///biological_process+++GO:0009225///nucleotide-sugar metabolic process 76357 76357 'Trmt5' mRNA 257.66 225.71 212.67 7.85 7.22 6.98 7.64 6.74 7.46 7.35 7.28 289.47 244.36 265.81 232.0133333 266.5466667 0.312678773 0.190079527 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008168///methyltransferase activity+++GO:0008175///tRNA methyltransferase activity+++GO:0009019///tRNA (guanine-N1-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0052906///tRNA (guanine(37)-N(1))-methyltransferase activity GO:0002939///tRNA N1-guanine methylation+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0070901///mitochondrial tRNA methylation 76365 76365 'Tbx18' mRNA 1089 1226 1014 12.47 13.8 12.32 16.13 12.96 14.11 12.86333333 14.4 1622 1273 1374 1109.666667 1423 4.28E-04 0.347475514 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090571///RNA polymerase II transcription repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001708///cell fate specification+++GO:0001756///somitogenesis+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0003163///sinoatrial node development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007605///sensory perception of sound+++GO:0009948///anterior/posterior axis specification+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0051145///smooth muscle cell differentiation+++GO:0060829///negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation+++GO:0060930///sinoatrial node cell fate commitment+++GO:0060931///sinoatrial node cell development+++GO:0072189///ureter development+++GO:0090103///cochlea morphogenesis+++GO:0098907///regulation of SA node cell action potential+++GO:2000729///positive regulation of mesenchymal cell proliferation involved in ureter development" 76366 76366 'Mtif3' mRNA 437.31 516.36 433.11 4.7 5.45 4.94 4.26 4.88 4.15 5.03 4.43 457.53 510.22 432.55 462.26 466.7666667 0.986416579 0.004429281 GO:0005739///mitochondrion "GO:0003743///translation initiation factor activity+++GO:0008135///translation factor activity, RNA binding+++GO:0043022///ribosome binding+++GO:0043024///ribosomal small subunit binding" GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly+++GO:0070124///mitochondrial translational initiation 76367 76367 'Trp53rkb' mRNA 131.31 124.9 136.31 2.57 2.46 3.77 2.41 2.4 2.81 2.933333333 2.54 126.09 113.53 130.49 130.84 123.37 0.747518754 -0.097901782 GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity GO:0006468///protein phosphorylation+++GO:0008033///tRNA processing+++GO:0016310///phosphorylation+++GO:0070525///tRNA threonylcarbamoyladenosine metabolic process 76373 76373 'Zfp773' mRNA 33.99 24.97 35.9 0.62 0.45 0.69 0.27 0.73 0.33 0.586666667 0.443333333 17 45.05 20 31.62 27.35 0.806986787 -0.176392241 05168///Herpes simplex virus 1 infection "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 76375 76375 'Det1' mRNA 193.97 194.63 135.79 4.15 4.49 3.21 2.63 3.23 3.35 3.95 3.07 136.02 157.34 159.86 174.7966667 151.0733333 0.392031462 -0.211482626 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex "GO:0031625///ubiquitin protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0016567///protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0065003///protein-containing complex assembly 76376 76376 'Slc24a2' mRNA 34 26 37 0.17 0.13 0.2 0.14 0.16 0.18 0.166666667 0.16 32 36 40 32.33333333 36 0.815602368 0.138998741 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane "GO:0005262///calcium channel activity+++GO:0008273///calcium, potassium:sodium antiporter activity+++GO:0015297///antiporter activity" GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0007601///visual perception+++GO:0007602///phototransduction+++GO:0007612///learning+++GO:0007613///memory+++GO:0034220///ion transmembrane transport+++GO:0035725///sodium ion transmembrane transport+++GO:0036368///cone photoresponse recovery+++GO:0055085///transmembrane transport+++GO:0060291///long-term synaptic potentiation+++GO:0060292///long-term synaptic depression+++GO:0065003///protein-containing complex assembly+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0071486///cellular response to high light intensity+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:0098703///calcium ion import across plasma membrane 76380 76380 'Cep112' mRNA 310 321 243 5.1 5.16 4.14 2.84 2.32 2.52 4.8 2.56 194 162 173 291.3333333 176.3333333 2.05E-05 -0.732518718 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0060077///inhibitory synapse GO:0003674///molecular_function GO:0097120///receptor localization to synapse 76382 76382 '1700012A03Rik' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76383 76383 'H2al1m' mRNA 1 2 0 0.16 0.31 0 0 0.57 0 0.156666667 0.19 0 4 0 1 1.333333333 0.888377162 0.458935387 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 76389 76389 'Ankrd36' mRNA 0 1 0 0 0.02 0 0 0.01 0.01 0.006666667 0.006666667 0 1 1 0.333333333 0.666666667 0.863090843 0.898162336 GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process 76406 76406 'Tex45' mRNA 3 1 3 0.23 0.07 0.17 0.2 0.07 0.04 0.156666667 0.103333333 4 2 1 2.333333333 2.333333333 0.995389082 -0.030810941 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76408 76408 'Abcc3' mRNA 39 32 46 0.42 0.34 0.52 5.96 5.55 5.29 0.426666667 5.6 645 586 554 39 595 4.42E-93 3.916492471 01523///Antifolate resistance+++02010///ABC transporters+++04976///Bile secretion GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015164///glucuronoside transmembrane transporter activity+++GO:0015431///glutathione S-conjugate-exporting ATPase activity+++GO:0015432///bile acid-exporting ATPase activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042910///xenobiotic transmembrane transporter activity+++GO:0071714///icosanoid transmembrane transporter activity" GO:0006855///drug transmembrane transport+++GO:0015721///bile acid and bile salt transport+++GO:0015722///canalicular bile acid transport+++GO:0015779///glucuronoside transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport+++GO:0071716///leukotriene transport+++GO:0098656///anion transmembrane transport 76411 76411 'Ift43' mRNA 960 879 863 80.54 73.11 76.84 49.06 50.38 52.68 76.83 50.70666667 669 669 694 900.6666667 677.3333333 2.17E-05 -0.422285716 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0015630///microtubule cytoskeleton+++GO:0030991///intraciliary transport particle A+++GO:0034451///centriolar satellite+++GO:0042995///cell projection GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly 76415 76415 'Fam187b' mRNA 253 255 289 13.9 12.48 15.22 2.99 5.07 4.14 13.86666667 4.066666667 69 114 93 265.6666667 92 2.10E-12 -1.542000582 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76416 76416 'Znrd1as' mRNA 214 229 188 12.53 13.26 12.16 7.76 7.46 10.22 12.65 8.48 146 137 186 210.3333333 156.3333333 0.03523618 -0.436596302 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76421 76421 '1700028K03Rik' mRNA 42 31.08 32 0.74 0.54 0.68 0.25 0.13 0.19 0.653333333 0.19 16 8 12 35.02666667 12 0.004344157 -1.558946052 GO:0005694///chromosome GO:0005515///protein binding GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0051321///meiotic cell cycle 76422 76422 'Mroh3' mRNA 13 5 4 0.23 0.08 0.08 0.08 0.03 0.03 0.13 0.046666667 5 2 2 7.333333333 3 0.319781254 -1.297359954 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76425 76425 'Gid8' mRNA 2787.07 2831 2726.97 34.17 34.17 35.34 26.59 25.15 25.21 34.56 25.65 2504 2286.19 2293.92 2781.68 2361.37 2.32E-04 -0.248977197 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction GO:0042803///protein homodimerization activity GO:0008284///positive regulation of cell proliferation+++GO:0016055///Wnt signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway 76426 76426 'Fam209' mRNA 3 2 0 0.34 0.23 0 0 0.2 0.31 0.19 0.17 0 2 3 1.666666667 1.666666667 0.998410559 0.029450312 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76429 76429 'Lhpp' mRNA 226 249 227 8.56 9.13 8.77 10.98 11.99 12.38 8.82 11.78333333 345 350 378 234 357.6666667 6.08E-05 0.601408741 00190///Oxidative phosphorylation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck GO:0000287///magnesium ion binding+++GO:0004427///inorganic diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0101006///protein histidine phosphatase activity GO:0006470///protein dephosphorylation+++GO:0006796///phosphate-containing compound metabolic process+++GO:0016311///dephosphorylation 76438 76438 'Rftn1' mRNA 54 55 51 1.05 1.06 1.07 8.93 8.85 10.6 1.06 9.46 525 509 604 53.33333333 546 4.56E-78 3.345278239 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0045121///membrane raft GO:0003725///double-stranded RNA binding GO:0001765///membrane raft assembly+++GO:0002457///T cell antigen processing and presentation+++GO:0032596///protein transport into membrane raft+++GO:0032740///positive regulation of interleukin-17 production+++GO:0033227///dsRNA transport+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0040010///positive regulation of growth rate+++GO:0043330///response to exogenous dsRNA+++GO:0050852///T cell receptor signaling pathway+++GO:0050853///B cell receptor signaling pathway+++GO:1903044///protein localization to membrane raft 76441 76441 'Daam2' mRNA 249 256 184 2.23 2.24 1.76 0.7 0.6 0.84 2.076666667 0.713333333 93 75 106 229.6666667 91.33333333 4.26E-10 -1.336797012 04310///Wnt signaling pathway GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0007368///determination of left/right symmetry+++GO:0016043///cellular component organization+++GO:0016055///Wnt signaling pathway+++GO:0021516///dorsal spinal cord development+++GO:0030036///actin cytoskeleton organization+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000050///regulation of non-canonical Wnt signaling pathway 76448 76448 'Ppp1r18' mRNA 167 191 120 3.28 3.69 2.47 20.69 20.7 20.9 3.146666667 20.76333333 1182 1146 1158 159.3333333 1162 2.29E-115 2.860306224 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003674///molecular_function+++GO:0003779///actin binding+++GO:0019902///phosphatase binding GO:0008150///biological_process 76453 76453 'Prss23' mRNA 2421 2489 2553 70.67 72.18 80.42 65.97 66.69 69.43 74.42333333 67.36333333 2588 2513 2629 2487.666667 2576.666667 0.708247107 0.03718065 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 76454 76454 'Fbxo31' mRNA 376 370 168 4.61 4.46 2.2 1.44 1.96 2.14 3.756666667 1.846666667 134 180 194 304.6666667 169.3333333 0.001031026 -0.840191897 GO:0005813///centrosome+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043025///neuronal cell body GO:0030332///cyclin binding GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:2001224///positive regulation of neuron migration 76457 76457 'Ccdc134' mRNA 366 318 332 10.16 8.7 9.77 7.19 6.99 7.09 9.543333333 7.09 298 283 285 338.6666667 288.6666667 0.128079411 -0.242955813 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0003674///molecular_function GO:0001525///angiogenesis+++GO:0001890///placenta development+++GO:0021591///ventricular system development+++GO:0035162///embryonic hemopoiesis+++GO:1990402///embryonic liver development 76459 76459 'Car12' mRNA 6551 6922 6681 94.49 97.99 101.81 28.46 28.46 26.22 98.09666667 27.71333333 2276 2217 2030 6718 2174.333333 5.60E-144 -1.640138698 00910///Nitrogen metabolism GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process+++GO:0006885///regulation of pH+++GO:0015670///carbon dioxide transport+++GO:0055064///chloride ion homeostasis 76464 76464 'Knl1' mRNA 54.42 50.99 86.12 0.22 0.2 0.37 1.32 1.18 1.3 0.263333333 1.266666667 281.28 258.47 243.13 63.84333333 260.96 1.37E-17 2.018718938 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body" GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0010923///negative regulation of phosphatase activity+++GO:0034501///protein localization to kinetochore+++GO:0051301///cell division 76467 76467 'Msrb2' mRNA 829 832 833 42.55 41.94 45.4 37.36 35.07 36.15 43.29666667 36.19333333 841 766 780 831.3333333 795.6666667 0.524912089 -0.076461133 GO:0005737///cytoplasm+++GO:0005739///mitochondrion "GO:0003779///actin binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0033743///peptide-methionine (R)-S-oxide reductase activity+++GO:0033745///L-methionine-(R)-S-oxide reductase activity+++GO:0046872///metal ion binding" GO:0006979///response to oxidative stress+++GO:0030041///actin filament polymerization+++GO:0030091///protein repair 76469 76469 'Cmya5' mRNA 35 33 15 0.15 0.14 0.07 0.12 0.16 0.16 0.12 0.146666667 32 41 40 27.66666667 37.66666667 0.406941291 0.448760879 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016607///nuclear speck+++GO:0031430///M band+++GO:0043034///costamere+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0014733///regulation of skeletal muscle adaptation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade 76477 76477 'Pcolce2' mRNA 348 388 394 10.7 11.76 12.85 8.48 8.28 8.96 11.77 8.573333333 317 302 324 376.6666667 314.3333333 0.073886488 -0.274780083 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0016504///peptidase activator activity GO:0010952///positive regulation of peptidase activity+++GO:1990830///cellular response to leukemia inhibitory factor 76478 76478 'Haus8' mRNA 216.5 227.96 219.74 6.76 6.91 7.34 16.02 15.34 15.2 7.003333333 15.52 567.08 537.23 504.04 221.4 536.1166667 7.00E-22 1.268060499 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005880///nuclear microtubule+++GO:0070652///HAUS complex+++GO:1990498///mitotic spindle microtubule GO:0003674///molecular_function+++GO:0008017///microtubule binding GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0051301///cell division 76479 76479 'Smndc1' mRNA 661 583 531 17.71 15.54 15.26 19.11 16.82 18.02 16.17 17.98333333 808 693 746 591.6666667 749 0.003945314 0.329533196 03040///Spliceosome GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016607///nuclear speck GO:0003723///RNA binding GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing 76482 76482 'Rmc1' mRNA 451 458 376.6 11.85 11.79 10.54 11.86 14.78 13.53 11.39333333 13.39 516.01 628.07 570.46 428.5333333 571.5133333 0.002189743 0.40900526 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0035658///Mon1-Ccz1 complex GO:0006914///autophagy+++GO:0010506///regulation of autophagy 76483 76483 'Lmf1' mRNA 1119 1188 1062 33.61 35.25 33.92 35.75 36.09 35.84 34.26 35.89333333 1346 1322 1310 1123 1326 0.0060382 0.229187756 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0006641///triglyceride metabolic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0033578///protein glycosylation in Golgi+++GO:0034382///chylomicron remnant clearance+++GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0051604///protein maturation+++GO:0090181///regulation of cholesterol metabolic process+++GO:0090207///regulation of triglyceride metabolic process 76484 76484 'Kndc1' mRNA 344 358 276 2.48 2.54 2.11 0.31 0.31 0.23 2.376666667 0.283333333 49 49 36 326 44.66666667 1.21E-41 -2.875011223 GO:0030425///dendrite+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity GO:0001934///positive regulation of protein phosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0016310///phosphorylation+++GO:0021707///cerebellar granule cell differentiation+++GO:0048814///regulation of dendrite morphogenesis+++GO:0050773///regulation of dendrite development+++GO:0050790///regulation of catalytic activity 76485 76485 'Glt8d1' mRNA 873.11 861.53 770.33 26.78 26.59 25.08 19.62 18.38 18.88 26.15 18.96 702.15 646.35 655.3 834.99 667.9333333 8.19E-04 -0.332613961 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" 76486 76486 'Ly6k' mRNA 13 12 3 1.16 1.06 0.28 1.95 1.04 1.21 0.833333333 1.4 25 13 15 9.333333333 17.66666667 0.263526555 0.921595733 GO:0001669///acrosomal vesicle+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045121///membrane raft GO:0005515///protein binding GO:0007339///binding of sperm to zona pellucida+++GO:0030317///flagellated sperm motility 76487 76487 'Ppp1r3g' mRNA 15 14 8 0.36 0.34 0.22 0.16 0.16 0.22 0.306666667 0.18 8 7 10 12.33333333 8.333333333 0.544901063 -0.567405101 GO:0000164///protein phosphatase type 1 complex+++GO:0005737///cytoplasm GO:0008157///protein phosphatase 1 binding+++GO:0019903///protein phosphatase binding+++GO:2001069///glycogen binding GO:0005979///regulation of glycogen biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:2000467///positive regulation of glycogen (starch) synthase activity 76491 76491 'Abhd14b' mRNA 3977 4061 3807 158.35 159.62 160.93 82.5 84.47 81.7 159.6333333 82.89 2384 2374 2292 3948.333333 2350 4.32E-37 -0.759832931 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0016787///hydrolase activity GO:0045944///positive regulation of transcription by RNA polymerase II 76497 76497 'Ppp1r11' mRNA 1342 1260 1138 46.48 43.02 41.81 41.56 41.29 41.05 43.77 41.3 1379 1337 1318 1246.666667 1344.666667 0.293040401 0.099229292 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004864///protein phosphatase inhibitor activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0001818///negative regulation of cytokine production+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0050830///defense response to Gram-positive bacterium 76498 76498 'Paqr4' mRNA 1737.39 1639.09 1600.95 38.6 36.01 37.73 27.38 23.46 24.54 37.44666667 25.12666667 1410.62 1179.51 1219.2 1659.143333 1269.776667 2.79E-06 -0.399019485 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0038023///signaling receptor activity 76499 76499 'Clasp2' mRNA 1863 1883 1706 15.76 16.04 15.6 10.9 10.27 10.12 15.8 10.43 1453 1390 1339 1817.333333 1394 8.46E-08 -0.39334579 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000922///spindle pole+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0031252///cell leading edge+++GO:0032587///ruffle membrane+++GO:0042995///cell projection+++GO:0044295///axonal growth cone+++GO:0045180///basal cortex+++GO:0072686///mitotic spindle+++GO:1903754///cortical microtubule plus-end" GO:0002162///dystroglycan binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0051010///microtubule plus-end binding+++GO:0051015///actin filament binding+++GO:1990782///protein tyrosine kinase binding "GO:0000226///microtubule cytoskeleton organization+++GO:0006903///vesicle targeting+++GO:0007020///microtubule nucleation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0010458///exit from mitosis+++GO:0010470///regulation of gastrulation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0016477///cell migration+++GO:0030516///regulation of axon extension+++GO:0031023///microtubule organizing center organization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0031113///regulation of microtubule polymerization+++GO:0032886///regulation of microtubule-based process+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034453///microtubule anchoring+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0040001///establishment of mitotic spindle localization+++GO:0045921///positive regulation of exocytosis+++GO:0051301///cell division+++GO:0051321///meiotic cell cycle+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0072659///protein localization to plasma membrane+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0090307///mitotic spindle assembly+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis+++GO:1905477///positive regulation of protein localization to membrane" 76500 76500 'Ip6k2' mRNA 883 879 767 36.6 36.21 34.87 24.18 22.23 24.61 35.89333333 23.67333333 667 596 648 843 637 3.67E-05 -0.414434917 04070///Phosphatidylinositol signaling system GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0097243///flavonoid binding GO:0006629///lipid metabolic process+++GO:0006817///phosphate ion transport+++GO:0016310///phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0032958///inositol phosphate biosynthetic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043647///inositol phosphate metabolic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:1905396///cellular response to flavonoid 76501 76501 'Commd9' mRNA 791 792 814 41.52 41.06 45.33 50.45 49.25 51.28 42.63666667 50.32666667 1103 1050 1084 799 1079 6.80E-06 0.420166903 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle GO:0003674///molecular_function GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0042632///cholesterol homeostasis 76507 76507 'Aoc1' mRNA 4 7 14 0.08 0.14 0.31 0.4 0.77 0.04 0.176666667 0.403333333 22 42 2 8.333333333 22 0.152733657 1.373238252 00330///Arginine and proline metabolism+++00340///Histidine metabolism+++00380///Tryptophan metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0070062///extracellular exosome "GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0008131///primary amine oxidase activity+++GO:0008201///heparin binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0048038///quinone binding+++GO:0052597///diamine oxidase activity+++GO:0052598///histamine oxidase activity+++GO:0052599///methylputrescine oxidase activity+++GO:0052600///propane-1,3-diamine oxidase activity+++GO:0097159///organic cyclic compound binding" GO:0009308///amine metabolic process+++GO:0009445///putrescine metabolic process+++GO:0015898///amiloride transport+++GO:0035874///cellular response to copper ion starvation+++GO:0046677///response to antibiotic+++GO:0071280///cellular response to copper ion+++GO:0071420///cellular response to histamine+++GO:0097185///cellular response to azide 76509 76509 'Plet1' mRNA 380 367 348 11.83 11.26 11.49 20.55 19.53 20.17 11.52666667 20.08333333 759 704 721 365 728 2.08E-19 0.984558729 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031225///anchored component of membrane "GO:0001953///negative regulation of cell-matrix adhesion+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0035313///wound healing, spreading of epidermal cells" 76510 76510 'Trappc9' mRNA 1844.52 1871.18 1844.27 25.87 25.38 26.7 15.89 14.81 14.59 25.98333333 15.09666667 1325.38 1215.12 1180.16 1853.323333 1240.22 2.97E-14 -0.592647913 GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0030008///TRAPP complex GO:0005515///protein binding GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity 76522 76522 'Lsm8' mRNA 541 491 487 50.23 45.23 47.99 62.34 59.37 54.42 47.81666667 58.71 768 712 647 506.3333333 709 3.67E-05 0.473451012 03018///RNA degradation+++03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0031417///NatC complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071011///precatalytic spliceosome+++GO:0120115///Lsm2-8 complex GO:0003674///molecular_function+++GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0043066///negative regulation of apoptotic process" 76524 76524 'Cln6' mRNA 1827 1754 874 48.21 45.59 24.47 15.7 20.76 19.82 39.42333333 18.76 684 883 836 1485 801 0.011030097 -0.883967131 GO:0005730///nucleolus+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft GO:0035727///lysophosphatidic acid binding+++GO:0042803///protein homodimerization activity+++GO:0120146///sulfatide binding GO:0001573///ganglioside metabolic process+++GO:0007040///lysosome organization+++GO:0007042///lysosomal lumen acidification+++GO:0007601///visual perception+++GO:0008203///cholesterol metabolic process+++GO:0030203///glycosaminoglycan metabolic process+++GO:0031987///locomotion involved in locomotory behavior+++GO:0044265///cellular macromolecule catabolic process+++GO:0045862///positive regulation of proteolysis 76527 76527 'Il34' mRNA 575.97 527.67 540.2 18.01 16.61 18.07 26.06 26 24.86 17.56333333 25.64 938.18 896.24 867.54 547.9466667 900.6533333 2.95E-12 0.705524876 04060///Cytokine-cytokine receptor interaction+++04061///Viral protein interaction with cytokine and cytokine receptor GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005125///cytokine activity+++GO:0005157///macrophage colony-stimulating factor receptor binding+++GO:0008083///growth factor activity+++GO:0042802///identical protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045087///innate immune response+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045657///positive regulation of monocyte differentiation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0061514///interleukin-34-mediated signaling pathway+++GO:0061518///microglial cell proliferation+++GO:0120041///positive regulation of macrophage proliferation 76539 76539 'Fam204a' mRNA 793 738 749 23.66 21.81 24.34 15.32 18.56 17.24 23.27 17.04 582 677 629 760 629.3333333 0.015707132 -0.283039699 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76547 76547 'Tmem101' mRNA 599 630 576 22.26 23.07 22.73 21.77 17.61 19.35 22.68666667 19.57666667 675 532 579 601.6666667 595.3333333 0.863090843 -0.028100208 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane 76551 76551 'Ccdc6' mRNA 838 842.7 1150 8.76 8.69 12.69 8.66 9.59 9.77 10.04666667 9.34 948.22 1032.03 1042.01 943.5666667 1007.42 0.685193386 0.07489572 05200///Pathways in cancer+++05216///Thyroid cancer GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding GO:0008150///biological_process 76559 76559 'Atg2b' mRNA 828 802 687 4.38 4.42 3.73 3.39 3.04 3.41 4.176666667 3.28 637 603 699 772.3333333 646.3333333 0.018398627 -0.26586653 04136///Autophagy - other+++04140///Autophagy - animal+++05010///Alzheimer disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases GO:0000407///phagophore assembly site+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019898///extrinsic component of membrane+++GO:0034045///phagophore assembly site membrane GO:0005515///protein binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0120013///intermembrane lipid transfer activity GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0044805///late nucleophagy+++GO:0061709///reticulophagy+++GO:0120009///intermembrane lipid transfer 76560 76560 'Prss8' mRNA 3523 3570.82 3380 110.71 110.64 112.08 68.39 71.29 67.43 111.1433333 69.03666667 2518 2549 2398 3491.273333 2488.333333 1.94E-15 -0.499764398 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017080///sodium channel regulator activity GO:0001942///hair follicle development+++GO:0006508///proteolysis+++GO:0010765///positive regulation of sodium ion transport+++GO:0070633///transepithelial transport+++GO:1902307///positive regulation of sodium ion transmembrane transport 76561 76561 'Snx7' mRNA 304 368 301 7.93 9.46 8.37 11.92 13.06 14.04 8.586666667 13.00666667 526 560 595 324.3333333 560.3333333 2.62E-09 0.780082396 GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding GO:0015031///protein transport 76563 76563 'Qrsl1' mRNA 213 232 243 6.24 6.77 7.66 6.53 6.05 5.97 6.89 6.183333333 258 232 227 229.3333333 239 0.86135211 0.044685557 00970///Aminoacyl-tRNA biosynthesis GO:0005739///mitochondrion+++GO:0030956///glutamyl-tRNA(Gln) amidotransferase complex "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016874///ligase activity+++GO:0016884///carbon-nitrogen ligase activity, with glutamine as amido-N-donor+++GO:0050567///glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity" GO:0006412///translation+++GO:0031647///regulation of protein stability+++GO:0032543///mitochondrial translation+++GO:0070681///glutaminyl-tRNAGln biosynthesis via transamidation 76566 76566 'Rflnb' mRNA 13781 14558 7424 213.35 221.73 121.92 39.59 56.41 55.09 185.6666667 50.36333333 2943 4096 3966 11921 3668.333333 1.84E-08 -1.693725369 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0032432///actin filament bundle GO:0031005///filamin binding GO:0001837///epithelial to mesenchymal transition+++GO:0030036///actin cytoskeleton organization+++GO:0048705///skeletal system morphogenesis+++GO:0061181///regulation of chondrocyte development+++GO:0061182///negative regulation of chondrocyte development+++GO:0061572///actin filament bundle organization+++GO:1900158///negative regulation of bone mineralization involved in bone maturation 76568 76568 'Ift46' mRNA 1047.8 1102.65 1060.78 24.39 25.63 26.58 26.64 23.22 25.12 25.53333333 24.99333333 1297.11 1107.28 1175.82 1070.41 1193.403333 0.143827373 0.144134115 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0097546///ciliary base GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0015031///protein transport+++GO:0031647///regulation of protein stability+++GO:0035082///axoneme assembly+++GO:0042073///intraciliary transport+++GO:0044782///cilium organization+++GO:0060271///cilium assembly+++GO:0060285///cilium-dependent cell motility+++GO:1902017///regulation of cilium assembly 76571 76571 'Styxl1' mRNA 151 140 140 5.31 4.87 5.47 1.72 2.18 2.67 5.216666667 2.19 57 63 82 143.6666667 67.33333333 1.36E-05 -1.103930372 GO:0005739///mitochondrion GO:0001691///pseudophosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0019903///protein phosphatase binding GO:0006470///protein dephosphorylation+++GO:0010976///positive regulation of neuron projection development+++GO:0016311///dephosphorylation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0062030///negative regulation of stress granule assembly+++GO:2001242///regulation of intrinsic apoptotic signaling pathway+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway 76572 76572 'Rbmxl2' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding "GO:0048026///positive regulation of mRNA splicing, via spliceosome" 76573 76573 'Spatc1l' mRNA 6 8 6 0.07 0.36 0.11 0.05 0.05 0.05 0.18 0.05 1 2 1 6.666666667 1.333333333 0.101646778 -2.327043831 GO:0005813///centrosome+++GO:0097224///sperm connecting piece GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0042802///identical protein binding GO:0001934///positive regulation of protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0008154///actin polymerization or depolymerization+++GO:0010739///positive regulation of protein kinase A signaling+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity 76574 76574 'Mfsd2a' mRNA 1636 1851 1516 42.36 47.41 41.25 19.14 19.46 20.27 43.67333333 19.62333333 854 848 876 1667.666667 859.3333333 1.40E-30 -0.965378332 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005215///transporter activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0015245///fatty acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0051978///lysophospholipid transporter activity+++GO:1901480///oleate transmembrane transporter activity GO:0003406///retinal pigment epithelium development+++GO:0006869///lipid transport+++GO:0007420///brain development+++GO:0008594///photoreceptor cell morphogenesis+++GO:0008643///carbohydrate transport+++GO:0009267///cellular response to starvation+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0015711///organic anion transport+++GO:0015908///fatty acid transport+++GO:0015909///long-chain fatty acid transport+++GO:0021766///hippocampus development+++GO:0030307///positive regulation of cell growth+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0035633///maintenance of permeability of blood-brain barrier+++GO:0035845///photoreceptor cell outer segment organization+++GO:0040014///regulation of multicellular organism growth+++GO:0045056///transcytosis+++GO:0050773///regulation of dendrite development+++GO:0050890///cognition+++GO:0051977///lysophospholipid transport+++GO:0055085///transmembrane transport+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0060856///establishment of blood-brain barrier+++GO:0061744///motor behavior+++GO:0071702///organic substance transport+++GO:0097009///energy homeostasis+++GO:0150011///regulation of neuron projection arborization+++GO:1990379///lipid transport across blood brain barrier+++GO:1990403///embryonic brain development+++GO:1990963///establishment of blood-retinal barrier 76577 76577 'Faf2' mRNA 1416 1523 1477 17.84 18.81 19.63 18.93 18.89 18.97 18.76 18.93 1732 1696 1673 1472 1700.333333 0.017655024 0.195544137 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035473///lipase binding+++GO:0043130///ubiquitin binding+++GO:0055102///lipase inhibitor activity "GO:0006986///response to unfolded protein+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034389///lipid droplet organization+++GO:0043086///negative regulation of catalytic activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process" 76580 76580 'Mib2' mRNA 1760 2057 1720 27.61 31.53 28.37 16.46 14.38 16.35 29.17 15.73 1185 1040 1166 1845.666667 1130.333333 1.99E-17 -0.717894853 05417///Lipid and atherosclerosis GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome GO:0003779///actin binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination 76582 76582 'Ipo11' mRNA 1676 1840 1879 20.84 22.49 24.77 17.05 16.66 17.7 22.7 17.13666667 1579 1507 1588 1798.333333 1558 0.014031889 -0.221119989 03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0061608///nuclear import signal receptor activity GO:0006606///protein import into nucleus+++GO:0006610///ribosomal protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport 76589 76589 'Unc5cl' mRNA 404 393 350 8.05 7.66 7.35 4.56 4.76 5.81 7.686666667 5.043333333 273 280 332 382.3333333 295 0.011752573 -0.38320346 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005042///netrin receptor activity+++GO:0008233///peptidase activity GO:0006508///proteolysis+++GO:0007165///signal transduction+++GO:0038007///netrin-activated signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046330///positive regulation of JNK cascade 76594 76594 'Dnajc18' mRNA 1629 1591 1691 16.78 16.12 18.47 12.57 11.99 12.98 17.12333333 12.51333333 1413 1314 1410 1637 1379 0.002715827 -0.261673893 GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0030544///Hsp70 protein binding GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0071218///cellular response to misfolded protein 76608 76608 'Hectd3' mRNA 901 958 863 10.58 11.07 10.75 8.26 9.15 9.66 10.8 9.023333333 809 876 917 907.3333333 867.3333333 0.542469019 -0.074745155 GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0019905///syntaxin binding GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 76612 76612 'Lrrc27' mRNA 929 878 900 22.07 20.82 22.57 4.19 4.8 4.4 21.82 4.463333333 200 219 196 902.3333333 205 4.26E-72 -2.150212863 GO:0003674///molecular_function 76614 76614 'Immt' mRNA 2736.08 2666.46 2677 55.65 53.4 57.82 54.69 52.22 50.78 55.62333333 52.56333333 3066 2871 2762.82 2693.18 2899.94 0.230583925 0.093577058 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath+++GO:0061617///MICOS complex GO:0005515///protein binding GO:0042407///cristae formation+++GO:0051560///mitochondrial calcium ion homeostasis 76626 76626 'Msi2' mRNA 1320 1247 1183 10.68 9.98 10.27 7.16 5.08 7.05 10.31 6.43 1015 719 974 1250 902.6666667 2.49E-05 -0.483053299 03015///mRNA surveillance pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008266///poly(U) RNA binding+++GO:0042802///identical protein binding GO:0048864///stem cell development 76630 76630 'Stambpl1' mRNA 387 364 439 11 10.19 13.25 12.06 12.73 12.38 11.48 12.39 487 497 484 396.6666667 489.3333333 0.050423017 0.28708933 GO:0005768///endosome+++GO:0016020///membrane GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070122///isopeptidase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0070536///protein K63-linked deubiquitination 76633 76633 'Lrmda' mRNA 17 15 23 1.02 0.95 1.03 1.64 3.54 2.82 1 2.666666667 41 61 52 18.33333333 51.33333333 0.001177205 1.470136303 GO:0005575///cellular_component GO:0003674///molecular_function GO:0030154///cell differentiation+++GO:0030318///melanocyte differentiation 76640 76640 '1700113H08Rik' mRNA 7 6 7 0.37 0.28 0.38 0.04 0.12 0 0.343333333 0.053333333 1 3 0 6.666666667 1.333333333 0.11658673 -2.330823427 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76645 76645 'Pkd1l2' mRNA 5 5 1 0.03 0.03 0.01 0.13 0.11 0.05 0.023333333 0.096666667 21 18 9 3.666666667 16 0.021131429 2.127056935 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001965///G-protein alpha-subunit binding+++GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding+++GO:0030246///carbohydrate binding GO:0050982///detection of mechanical stimulus+++GO:0070588///calcium ion transmembrane transport 76646 76646 'Wdr38' mRNA 179 194 199 9.27 10 10.81 0.83 0.69 1.07 10.02666667 0.863333333 18 15 22 190.6666667 18.33333333 1.42E-30 -3.392758622 GO:0005575///cellular_component GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 76650 76650 'Srxn1' mRNA 437 463 457 8.5 8.89 9.45 9.42 9.17 9.92 8.946666667 9.503333333 554 526 565 452.3333333 548.3333333 0.034358628 0.264960739 GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016209///antioxidant activity+++GO:0016491///oxidoreductase activity+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors+++GO:0032542///sulfiredoxin activity" GO:0006979///response to oxidative stress+++GO:0034599///cellular response to oxidative stress+++GO:0098869///cellular oxidant detoxification 76651 76651 '1700122O11Rik' mRNA 0 1 0 0 0.09 0 0 0 0 0.03 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76652 76652 'Actrt3' mRNA 1 6 2 0.03 0.18 0.06 0.08 0.05 0.08 0.09 0.07 3 2 3 3 2.666666667 0.930111544 -0.169901675 GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0005515///protein binding 76653 76653 'Cby3' mRNA 2 7 7 0.2 0.7 0.75 0.35 0.18 0.27 0.55 0.266666667 4 2 3 5.333333333 3 0.572080699 -0.854273978 GO:0003674///molecular_function 76654 76654 'Upp2' mRNA 9 11 8 0.17 0.26 0.17 0.03 0.05 0.05 0.2 0.043333333 2 2 3.79 9.333333333 2.596666667 0.07731978 -2.006533983 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045098///type III intermediate filament "GO:0003824///catalytic activity+++GO:0004850///uridine phosphorylase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0042802///identical protein binding+++GO:0047847///deoxyuridine phosphorylase activity" GO:0006218///uridine catabolic process+++GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0009116///nucleoside metabolic process+++GO:0009166///nucleotide catabolic process+++GO:0044206///UMP salvage+++GO:0046050///UMP catabolic process 76658 76658 '1700123K08Rik' mRNA 1 2 5 0.08 0.16 0.31 0 0 0 0.183333333 0 0 0 0 2.666666667 0 0.13645269 -3.900057995 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0008150///biological_process+++GO:0050790///regulation of catalytic activity 76668 76668 'Mdh1b' mRNA 154 147 153 5.19 4.9 5.5 0.68 0.88 0.49 5.196666667 0.683333333 23 29 16 151.3333333 22.66666667 1.15E-19 -2.751463865 "GO:0003824///catalytic activity+++GO:0016491///oxidoreductase activity+++GO:0016615///malate dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0030060///L-malate dehydrogenase activity" GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006107///oxaloacetate metabolic process+++GO:0006108///malate metabolic process+++GO:0006734///NADH metabolic process 76670 76670 'Cfap70' mRNA 391 429 444 6.13 6.6 7.47 1.1 0.67 0.77 6.733333333 0.846666667 82 49 56 421.3333333 62.33333333 5.20E-45 -2.774253558 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0031514///motile cilium+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0036157///outer dynein arm+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0060271///cilium assembly 76681 76681 'Trim12a' mRNA 115.06 111.47 100.43 3.57 3.27 3.31 3.37 4.71 3.73 3.383333333 3.936666667 122.1 153.49 123.28 108.9866667 132.9566667 0.29196828 0.279670127 GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990462///omegasome "GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0038187///pattern recognition receptor activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity" "GO:0000209///protein polyubiquitination+++GO:0002218///activation of innate immune response+++GO:0006914///autophagy+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0031664///regulation of lipopolysaccharide-mediated signaling pathway+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0070534///protein K63-linked ubiquitination+++GO:1902187///negative regulation of viral release from host cell" 76686 76686 'Clip3' mRNA 1258 1208 1135 20.56 19.44 19.69 12.44 10.78 12.37 19.89666667 11.86333333 876 741 843 1200.333333 820 7.45E-10 -0.561649018 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0032588///trans-Golgi network membrane+++GO:0035371///microtubule plus-end+++GO:0045121///membrane raft+++GO:0055038///recycling endosome membrane GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0035594///ganglioside binding+++GO:0051010///microtubule plus-end binding GO:0001934///positive regulation of protein phosphorylation+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0031115///negative regulation of microtubule polymerization+++GO:0031122///cytoplasmic microtubule organization+++GO:0043065///positive regulation of apoptotic process+++GO:0044091///membrane biogenesis+++GO:0045444///fat cell differentiation+++GO:0045807///positive regulation of endocytosis+++GO:0072321///chaperone-mediated protein transport+++GO:0098840///protein transport along microtubule+++GO:1903078///positive regulation of protein localization to plasma membrane 76687 76687 'Spcs3' mRNA 1041 1127 1097 16.34 17.41 18.27 38.16 37.05 38.16 17.34 37.79 2797 2653 2709 1088.333333 2719.666667 8.13E-72 1.30858173 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0019082///viral protein processing+++GO:0045047///protein targeting to ER 76688 76688 'Arfrp1' mRNA 1687.67 1778.93 1659 36.2 37.57 37.76 28.34 28.83 29.54 37.17666667 28.90333333 1518.94 1509.6 1532.93 1708.533333 1520.49 0.022008886 -0.17982025 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding "GO:0006886///intracellular protein transport+++GO:0007369///gastrulation+++GO:0033365///protein localization to organelle+++GO:0034067///protein localization to Golgi apparatus+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0043001///Golgi to plasma membrane protein transport" 76703 76703 'Cpb1' mRNA 0 0 4 0 0 0.17 0.31 0.18 0.11 0.056666667 0.2 9 5 3 1.333333333 5.666666667 0.247508157 2.020029141 04972///Pancreatic secretion+++04974///Protein digestion and absorption GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis 76707 76707 'Clasp1' mRNA 3055.82 3272.1 2933.43 20.12 21.21 20.59 10.13 8.61 9.66 20.64 9.466666667 1777.28 1494.01 1655.52 3087.116667 1642.27 1.48E-38 -0.922507889 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005828///kinetochore microtubule+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005876///spindle microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0015630///microtubule cytoskeleton+++GO:0030981///cortical microtubule cytoskeleton+++GO:0031592///centrosomal corona+++GO:0045180///basal cortex+++GO:0072686///mitotic spindle" GO:0002162///dystroglycan binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0043515///kinetochore binding+++GO:0051010///microtubule plus-end binding "GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0006903///vesicle targeting+++GO:0007020///microtubule nucleation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0010458///exit from mitosis+++GO:0010470///regulation of gastrulation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0030953///astral microtubule organization+++GO:0031023///microtubule organizing center organization+++GO:0031111///negative regulation of microtubule polymerization or depolymerization+++GO:0034453///microtubule anchoring+++GO:0040001///establishment of mitotic spindle localization+++GO:0045921///positive regulation of exocytosis+++GO:0051294///establishment of spindle orientation+++GO:0051301///cell division+++GO:0051497///negative regulation of stress fiber assembly+++GO:0051893///regulation of focal adhesion assembly+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:0090307///mitotic spindle assembly+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis" 76709 76709 'Arpc2' mRNA 3796 4111 3185 154.89 164.85 137.92 313.86 307.17 306.79 152.5533333 309.2733333 8804 8509 8378 3697.333333 8563.666667 6.18E-79 1.20427901 04144///Endocytosis+++04530///Tight junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05132///Salmonella infection+++05135///Yersinia infection GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0009986///cell surface+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030141///secretory granule+++GO:0030426///growth cone+++GO:0031252///cell leading edge+++GO:0031941///filamentous actin+++GO:0032587///ruffle membrane+++GO:0035861///site of double-strand break+++GO:0036195///muscle cell projection membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043198///dendritic shaft+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0061825///podosome core+++GO:0061826///podosome ring+++GO:0061830///concave side of sperm head+++GO:0061834///actin filament branch point+++GO:0061835///ventral surface of cell+++GO:0090725///peripheral region of growth cone+++GO:0097440///apical dendrite+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0035254///glutamate receptor binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0051117///ATPase binding GO:0010592///positive regulation of lamellipodium assembly+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization+++GO:0030838///positive regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0051491///positive regulation of filopodium assembly+++GO:0070528///protein kinase C signaling+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0071803///positive regulation of podosome assembly+++GO:0072752///cellular response to rapamycin+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:2000814///positive regulation of barbed-end actin filament capping 76713 76713 'Slc6a21' mRNA 1 0 0 0.03 0 0 0.02 0 0 0.01 0.006666667 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015293///symporter activity GO:0035725///sodium ion transmembrane transport 76718 76718 'Catsperg2' mRNA 9.6 9.3 8.65 0.13 0.12 0.14 0.06 0.06 0.12 0.13 0.08 4.33 5.01 10.38 9.183333333 6.573333333 0.697747209 -0.459697447 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0097228///sperm principal piece GO:0005515///protein binding GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008150///biological_process+++GO:0030154///cell differentiation 76719 76719 'Kansl1' mRNA 1279 1370 1257 13.61 14.28 14.18 10.04 9.29 10.26 14.02333333 9.863333333 1087 989 1084 1302 1053.333333 2.08E-04 -0.317437949 "GO:0000123///histone acetyltransferase complex+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044545///NSL complex+++GO:0071339///MLL1 complex" GO:0035035///histone acetyltransferase binding GO:0006325///chromatin organization+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043984///histone H4-K16 acetylation 76722 76722 'Ckmt2' mRNA 0 5 1 0 0.2 0.04 0 0 0 0.08 0 0 0 0 2 0 0.307379952 -3.428807844 00330///Arginine and proline metabolism GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane "GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004111///creatine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:1901612///cardiolipin binding" GO:0006603///phosphocreatine metabolic process+++GO:0016310///phosphorylation+++GO:0046314///phosphocreatine biosynthetic process 76737 76737 'Creld2' mRNA 2618 2626 2497 115.16 113.99 116.53 99.48 92.12 90.1 115.2266667 93.9 2597 2346 2275 2580.333333 2406 0.138110855 -0.113314283 GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus GO:0003756///protein disulfide isomerase activity+++GO:0005201///extracellular matrix structural constituent+++GO:0005509///calcium ion binding+++GO:0016853///isomerase activity GO:0008150///biological_process 76740 76740 'Efr3a' mRNA 4157 4350 4246 42.34 43.57 45.88 25.12 23.09 23.26 43.93 23.82333333 2839 2550 2544 4251 2644.333333 1.37E-26 -0.698363418 GO:0001533///cornified envelope+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0042803///protein homodimerization activity GO:0072659///protein localization to plasma membrane+++GO:0098609///cell-cell adhesion 76742 76742 'Snx27' mRNA 940.24 945.4 589.03 7.95 8 5.3 6.42 6.32 7.35 7.083333333 6.696666667 867.14 818.81 937.89 824.89 874.6133333 0.646077408 0.081634868 GO:0001772///immunological synapse+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030904///retromer complex+++GO:0031901///early endosome membrane+++GO:0071203///WASH complex GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0035255///ionotropic glutamate receptor binding GO:0006886///intracellular protein transport+++GO:0007165///signal transduction+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0032456///endocytic recycling+++GO:0061951///establishment of protein localization to plasma membrane+++GO:0099638///endosome to plasma membrane protein transport+++GO:1903609///negative regulation of inward rectifier potassium channel activity+++GO:1904719///positive regulation of AMPA glutamate receptor clustering 76743 76743 'Gje1' mRNA 11.21 5.98 3.96 0.42 0.24 0.17 1.48 1.77 1.53 0.276666667 1.593333333 44.4 50.88 45.84 7.05 47.04 5.37E-07 2.868489278 GO:0005886///plasma membrane+++GO:0005922///connexin complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005243///gap junction channel activity GO:0000902///cell morphogenesis+++GO:0002088///lens development in camera-type eye+++GO:0007154///cell communication+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0035265///organ growth 76747 76747 'Dapl1' mRNA 130 125 123 17.76 17.02 17.83 7.79 13.07 11.69 17.53666667 10.85 65 106 94 126 88.33333333 0.062259519 -0.520320008 GO:0005575///cellular_component GO:0070513///death domain binding GO:0006915///apoptotic process+++GO:0010507///negative regulation of autophagy+++GO:0030154///cell differentiation+++GO:0034198///cellular response to amino acid starvation+++GO:0097190///apoptotic signaling pathway 76757 76757 'Trdn' mRNA 243 267 235 3.04 3.12 3.18 0.22 0.23 0.46 3.113333333 0.303333333 12 13 18 248.3333333 14.33333333 3.20E-44 -4.124892146 04020///Calcium signaling pathway+++04260///Cardiac muscle contraction GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0034704///calcium channel complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding GO:0006874///cellular calcium ion homeostasis+++GO:0009617///response to bacterium+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0031122///cytoplasmic microtubule organization+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0060047///heart contraction+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090158///endoplasmic reticulum membrane organization 76763 76763 'Mospd2' mRNA 387 296 367 5.55 4.36 6 11.65 10.4 10.87 5.303333333 10.97333333 752 661 670 350 694.3333333 3.00E-13 0.972498721 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044232///organelle membrane contact site GO:0003674///molecular_function GO:0006935///chemotaxis+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0090026///positive regulation of monocyte chemotaxis 76773 76773 'Wdyhv1' mRNA 434 444 469 18.9 19.39 22.49 20.52 19.47 19.19 20.26 19.72666667 539 487 483 449 503 0.299487611 0.149251419 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0016787///hydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0070773///protein-N-terminal glutamine amidohydrolase activity" GO:0006464///cellular protein modification process+++GO:0030163///protein catabolic process 76775 76775 'Slc10a7' mRNA 1512.09 1657.59 1470.64 25.54 26.78 25.65 9.96 8.4 9.86 25.99 9.406666667 644.55 559.35 631.77 1546.773333 611.89 4.76E-53 -1.350219018 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane GO:0015125///bile acid transmembrane transporter activity+++GO:0015293///symporter activity GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0015721///bile acid and bile salt transport+++GO:0030210///heparin biosynthetic process+++GO:0034436///glycoprotein transport+++GO:0048193///Golgi vesicle transport+++GO:0055085///transmembrane transport+++GO:0060348///bone development 76779 76779 'Cluap1' mRNA 1007.61 950.99 1063 32.26 30.41 36.21 15.09 15.34 14.46 32.96 14.96333333 544.72 514.75 501.73 1007.2 520.4 1.25E-19 -0.969121736 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0030991///intraciliary transport particle A+++GO:0030992///intraciliary transport particle B+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097542///ciliary tip+++GO:0097546///ciliary base GO:0005515///protein binding GO:0001843///neural tube closure+++GO:0001947///heart looping+++GO:0007224///smoothened signaling pathway+++GO:0021508///floor plate formation+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0042073///intraciliary transport+++GO:0060271///cilium assembly+++GO:0060972///left/right pattern formation 76781 76781 'Mettl4' mRNA 898 903 767 6.97 7.34 6.51 3.67 3.87 4 6.94 3.846666667 542 537 542 856 540.3333333 2.07E-11 -0.672701059 GO:0005634///nucleus+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity+++GO:0016740///transferase activity GO:0001510///RNA methylation+++GO:0006325///chromatin organization+++GO:0032259///methylation+++GO:0032775///DNA methylation on adenine+++GO:0043484///regulation of RNA splicing+++GO:0090296///regulation of mitochondrial DNA replication+++GO:0120049///snRNA (adenine-N6)-methylation+++GO:1902275///regulation of chromatin organization+++GO:1903108///regulation of mitochondrial transcription 76784 76784 'Mtif2' mRNA 543.07 518.2 507.54 9.93 9.22 9.67 8.62 8.82 8.46 9.606666667 8.633333333 540.01 545.19 510.42 522.9366667 531.8733333 0.932291521 0.013141266 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008135///translation factor activity, RNA binding+++GO:0043024///ribosomal small subunit binding" GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly+++GO:0070124///mitochondrial translational initiation 76787 76787 'Ppfia3' mRNA 148 123 79 2.25 1.8 1.29 0.9 0.77 0.82 1.78 0.83 69 57 56 116.6666667 60.66666667 0.001495343 -0.947135117 GO:0001669///acrosomal vesicle+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0048786///presynaptic active zone+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098875///epididymosome+++GO:0098978///glutamatergic synapse GO:0003674///molecular_function GO:0007269///neurotransmitter secretion+++GO:0016079///synaptic vesicle exocytosis+++GO:0016081///synaptic vesicle docking+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050808///synapse organization 76788 76788 'Klhdc10' mRNA 650 702 720 5.57 5.85 6.54 4.62 4.04 4.43 5.986666667 4.363333333 629 531 579 690.6666667 579.6666667 0.027783928 -0.267752862 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0003674///molecular_function+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" GO:0016567///protein ubiquitination+++GO:0032874///positive regulation of stress-activated MAPK cascade 76789 76789 'Mzt1' mRNA 1164.29 1096.53 1049.98 28.92 26.82 27.69 17.28 16.09 17.37 27.81 16.91333333 800.01 726.01 779 1103.6 768.34 3.64E-09 -0.533260702 GO:0000931///gamma-tubulin large complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0008274///gamma-tubulin ring complex+++GO:0031021///interphase microtubule organizing center GO:0033566///gamma-tubulin complex localization+++GO:0051415///microtubule nucleation by interphase microtubule organizing center+++GO:0090307///mitotic spindle assembly 76792 76792 'Spring1' mRNA 797.72 826.67 792.83 16.56 16.89 17.45 15.95 14.87 16.39 16.96666667 15.73666667 883.84 804.9 879.74 805.74 856.16 0.525985885 0.075161183 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:2000640///positive regulation of SREBP signaling pathway 76793 76793 'Snip1' mRNA 719 678 676 17.13 15.93 17.05 12.89 13.19 13.32 16.70333333 13.13333333 622 623 622 691 622.3333333 0.159870737 -0.162756861 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0071005///U2-type precatalytic spliceosome GO:0003729///mRNA binding+++GO:0005515///protein binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:0035196///production of miRNAs involved in gene silencing by miRNA" 76795 76795 'Tbc1d9b' mRNA 2461.9 2452.03 2587.01 25.38 24.83 28.35 23.25 21.16 21.07 26.18666667 21.82666667 2592.92 2308.42 2270.93 2500.313333 2390.756667 0.395391975 -0.079980487 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005096///GTPase activator activity+++GO:0005509///calcium ion binding GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity 76797 76797 '2410137M14Rik' mRNA 0 1 0 0 0.08 0 0 0 0 0.026666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76799 76799 'Tmem234' mRNA 2108.71 2059.77 2093.95 79.11 76.58 83.54 89.82 92.16 96.3 79.74333333 92.76 2689.75 2696.89 2777.31 2087.476667 2721.316667 1.83E-07 0.370268173 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76800 76800 'Usp42' mRNA 497 554 427 5.13 5.64 4.67 3.65 3.57 3.73 5.146666667 3.65 406 388 402 492.6666667 398.6666667 0.018073282 -0.313385086 GO:0005634///nucleus+++GO:0005829///cytosol GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0016579///protein deubiquitination+++GO:0030154///cell differentiation+++GO:0042981///regulation of apoptotic process 76803 76803 '2410141K09Rik' mRNA 1 2 1 0.16 0.32 0.17 0.14 0.15 0 0.216666667 0.096666667 2 1 0 1.333333333 1 0.880306125 -0.427320006 "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 76804 76804 'Kdm4c' mRNA 847.98 795.76 810.04 10.61 9.76 10.45 8.11 8.11 8.72 10.27333333 8.313333333 754.71 737.93 778.12 817.9266667 756.92 0.274291463 -0.124214959 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific) GO:0001825///blastocyst formation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010628///positive regulation of gene expression+++GO:0019827///stem cell population maintenance+++GO:0033169///histone H3-K9 demethylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0070544///histone H3-K36 demethylation+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:2000736///regulation of stem cell differentiation 76808 76808 'Rpl18a' mRNA 8424 8458 7827 395.27 391.76 389.65 419.68 442.36 437 392.2266667 433.0133333 10268 10557 10340 8236.333333 10388.33333 3.39E-10 0.324501429 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0014069///postsynaptic density+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0042788///polysomal ribosome+++GO:0045202///synapse GO:0003735///structural constituent of ribosome GO:0002181///cytoplasmic translation+++GO:0006412///translation 76809 76809 'Bri3bp' mRNA 1479.75 1412.32 1177.72 11.18 10.48 9.43 7.79 7.31 7.98 10.36333333 7.693333333 1187.75 1089.96 1178.23 1356.596667 1151.98 0.0078818 -0.244659475 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 76813 76813 'Armc6' mRNA 309.93 294.95 306.3 7.88 7.36 8.21 10.29 8.88 10.33 7.816666667 9.833333333 466.14 394.27 447.58 303.7266667 435.9966667 2.56E-04 0.510018838 GO:0005829///cytosol GO:0003674///molecular_function GO:0002244///hematopoietic progenitor cell differentiation 76815 76815 'Calcoco2' mRNA 10 13 9 0.31 0.4 0.31 0.66 0.65 0.72 0.34 0.676666667 25.08 25 27 10.66666667 25.69333333 0.039163629 1.259603191 04137///Mitophagy - animal+++05131///Shigellosis+++05164///Influenza A GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016605///PML body+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm GO:0042803///protein homodimerization activity GO:0006914///autophagy+++GO:0034341///response to interferon-gamma+++GO:0098792///xenophagy+++GO:1901098///positive regulation of autophagosome maturation 76816 76816 'Sdccag8' mRNA 382.13 432.26 345.26 7.74 8.69 7.54 6.49 5.37 6.9 7.99 6.253333333 364.09 298.88 376.61 386.55 346.5266667 0.311486383 -0.168778022 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0030054///cell junction+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097733///photoreceptor cell cilium GO:0005515///protein binding GO:0001764///neuron migration+++GO:0007098///centrosome cycle+++GO:0030010///establishment of cell polarity+++GO:0030030///cell projection organization+++GO:0031023///microtubule organizing center organization+++GO:0035148///tube formation+++GO:1902017///regulation of cilium assembly 76820 76820 'Cyria' mRNA 1934 2071 2057.01 13.32 14.02 15.08 4.81 4.98 4.79 14.14 4.86 804 810.99 774 2020.67 796.33 1.22E-59 -1.356988821 GO:0016020///membrane GO:0003674///molecular_function+++GO:0031267///small GTPase binding GO:0008150///biological_process+++GO:0030833///regulation of actin filament polymerization 76824 76824 'Mtfr1l' mRNA 3148 3087 3228 90.08 86.39 98.02 70.59 76.61 73.55 91.49666667 73.58333333 2849 3008 2858 3154.333333 2905 0.102626206 -0.131803474 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0000266///mitochondrial fission+++GO:0009060///aerobic respiration 76826 76826 'Nubpl' mRNA 272 342 330 14.3 17.83 18.75 10.55 11.78 8.8 16.96 10.37666667 235 253 188 314.6666667 225.3333333 0.007025172 -0.495019954 GO:0005739///mitochondrion+++GO:0005886///plasma membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding" GO:0016226///iron-sulfur cluster assembly+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0070584///mitochondrion morphogenesis 76829 76829 'Dok5' mRNA 87 100 105 2.83 3.22 3.63 2.21 2.44 1.76 3.226666667 2.136666667 78 84 60 97.33333333 74 0.184661435 -0.409781998 GO:0005737///cytoplasm GO:0005515///protein binding GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030182///neuron differentiation+++GO:0043410///positive regulation of MAPK cascade+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway 76832 76832 'Hyls1' mRNA 28 36 19 0.99 1.26 0.72 1.54 1.99 2.27 0.99 1.933333333 50 63 71 27.66666667 61.33333333 0.004482636 1.148059489 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0097730///non-motile cilium GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0060271///cilium assembly 76843 76843 'Dtl' mRNA 8 5 8 0.1 0.06 0.11 1.68 1.91 1.84 0.09 1.81 152 168 161 7 160.3333333 4.06E-29 4.506006225 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0031965///nuclear membrane+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex "GO:0004842///ubiquitin-protein transferase activity+++GO:0030674///protein binding, bridging" GO:0000209///protein polyubiquitination+++GO:0006260///DNA replication+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0009411///response to UV+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0019985///translesion synthesis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint 76846 76846 'Rps9' mRNA 5437 5557 5102 551.76 559.98 549.52 715.81 723.33 740.93 553.7533333 726.69 8063 7928 8052 5365.333333 8014.333333 7.68E-30 0.568168273 03010///Ribosome+++05171///Coronavirus disease - COVID-19 GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0015935///small ribosomal subunit+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0045202///synapse+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding+++GO:0045182///translation regulator activity+++GO:1990932///5.8S rRNA binding GO:0006412///translation+++GO:0008284///positive regulation of cell proliferation+++GO:0045903///positive regulation of translational fidelity 76850 76850 'Ago4' mRNA 206 166 141 1.78 1.35 1.37 1.25 0.87 0.99 1.5 1.036666667 166.25 119 129 171 138.0833333 0.193472011 -0.319438084 04361///Axon regeneration GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016442///RISC complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070578///RISC-loading complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0035198///miRNA binding GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0007130///synaptonemal complex assembly+++GO:0007140///male meiotic nuclear division+++GO:0008584///male gonad development+++GO:0010501///RNA secondary structure unwinding+++GO:0010586///miRNA metabolic process+++GO:0022604///regulation of cell morphogenesis+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0035278///miRNA mediated inhibition of translation+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0043066///negative regulation of apoptotic process 76854 76854 'Gper1' mRNA 120 163 133 2.73 3.6 3.13 4.3 5.71 4.46 3.153333333 4.823333333 218 289 222 138.6666667 243 1.20E-04 0.801503805 01522///Endocrine resistance+++04915///Estrogen signaling pathway+++04929///GnRH secretion GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031966///mitochondrial membrane+++GO:0032591///dendritic spine membrane+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043198///dendritic shaft+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043679///axon terminus+++GO:0044327///dendritic spine head+++GO:0045095///keratin filament+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0048786///presynaptic active zone+++GO:0055037///recycling endosome+++GO:0098686///hippocampal mossy fiber to CA3 synapse GO:0003682///chromatin binding+++GO:0003707///steroid hormone receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005496///steroid binding+++GO:0030284///estrogen receptor activity+++GO:1903924///estradiol binding+++GO:1990239///steroid hormone binding GO:0001934///positive regulation of protein phosphorylation+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0002376///immune system process+++GO:0002695///negative regulation of leukocyte activation+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0007049///cell cycle+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007210///serotonin receptor signaling pathway+++GO:0007399///nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010948///negative regulation of cell cycle process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0019228///neuronal action potential+++GO:0030154///cell differentiation+++GO:0030263///apoptotic chromosome condensation+++GO:0030264///nuclear fragmentation involved in apoptotic nuclear change+++GO:0030335///positive regulation of cell migration+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0032024///positive regulation of insulin secretion+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0042311///vasodilation+++GO:0043065///positive regulation of apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043410///positive regulation of MAPK cascade+++GO:0045087///innate immune response+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050728///negative regulation of inflammatory response+++GO:0050769///positive regulation of neurogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0051726///regulation of cell cycle+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0071333///cellular response to glucose stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0071389///cellular response to mineralocorticoid stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1900121///negative regulation of receptor binding+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:1905152///positive regulation of voltage-gated sodium channel activity+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:2000724///positive regulation of cardiac vascular smooth muscle cell differentiation+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway 76856 76856 'Catsper3' mRNA 4 4 4 0.2 0.17 0.19 0 0.21 0.09 0.186666667 0.1 0 5 2 4 2.333333333 0.682110102 -0.7750752 GO:0001669///acrosomal vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0042995///cell projection GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030317///flagellated sperm motility+++GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0048240///sperm capacitation+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport 76857 76857 'Spopl' mRNA 646.04 634.79 531.04 4.35 4.11 3.63 3.08 3.02 3.45 4.03 3.183333333 520.55 501.71 515.87 603.9566667 512.71 0.039346689 -0.246336783 04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex GO:0031625///ubiquitin protein ligase binding GO:0016567///protein ubiquitination+++GO:0030162///regulation of proteolysis+++GO:0031397///negative regulation of protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 76863 76863 'Dcun1d5' mRNA 813.29 829.59 576.72 7.38 6.85 3.44 5 4.89 5.39 5.89 5.093333333 561.22 539.95 563.12 739.8666667 554.7633333 0.00100827 -0.420309185 GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton GO:0003674///molecular_function+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0032182///ubiquitin-like protein binding+++GO:0097602///cullin family protein binding GO:0001558///regulation of cell growth+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045116///protein neddylation+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000434///regulation of protein neddylation+++GO:2000436///positive regulation of protein neddylation 76866 76866 'Morn1' mRNA 1811.92 1807.57 1615.29 41.4 40.24 41.51 7.83 7.16 7.45 41.05 7.48 474.31 412.77 396.39 1744.926667 427.8233333 2.42E-113 -2.040286697 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76867 76867 'Rhbdd1' mRNA 878.01 954 812 12.39 13.39 12.55 8.18 8.59 8.37 12.77666667 8.38 704 695 707 881.3366667 702 5.80E-04 -0.337785872 GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031966///mitochondrial membrane+++GO:0044322///endoplasmic reticulum quality control compartment GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity "GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0010954///positive regulation of protein processing+++GO:0030154///cell differentiation+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0034620///cellular response to unfolded protein+++GO:0034644///cellular response to UV+++GO:0036503///ERAD pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0043687///post-translational protein modification+++GO:0045732///positive regulation of protein catabolic process+++GO:0048515///spermatid differentiation+++GO:0051047///positive regulation of secretion+++GO:1904211///membrane protein proteolysis involved in retrograde protein transport, ER to cytosol+++GO:2000254///regulation of male germ cell proliferation" 76872 76872 'Ccdc116' mRNA 3 14.11 12 0.04 0.19 0.17 0.24 0.07 0.19 0.133333333 0.166666667 24.07 7 16.06 9.703333333 15.71 0.479436418 0.670985894 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0008150///biological_process 76877 76877 'Rab36' mRNA 1687 1886 1678 24.31 26.77 26.17 6.21 6.4 7.46 25.75 6.69 508 490 582 1750.333333 526.6666667 1.04E-77 -1.74331838 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0015031///protein transport 76884 76884 'Cyfip2' mRNA 5628.4 5527 5082.72 44.72 43.33 42.84 18.64 17.58 19.02 43.63 18.41333333 2682.87 2462.88 2642 5412.706667 2595.916667 1.15E-78 -1.071335899 04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm GO:0000340///RNA 7-methylguanosine cap binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding GO:0000902///cell morphogenesis+++GO:0006915///apoptotic process+++GO:0007155///cell adhesion+++GO:0030833///regulation of actin filament polymerization+++GO:0031175///neuron projection development+++GO:0045862///positive regulation of proteolysis+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0097484///dendrite extension+++GO:0098609///cell-cell adhesion 76886 76886 'Fam81a' mRNA 98 117.01 74.82 1.88 2.21 1.52 1.16 1.04 1.6 1.87 1.266666667 70 60.72 94 96.61 74.90666667 0.262077261 -0.371985162 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76889 76889 'Coq8b' mRNA 740.89 689.96 659.42 17.2 15.6 15.51 20.05 17.71 21.01 16.10333333 19.59 961.74 827.79 967.2 696.7566667 918.91 1.72E-04 0.388088024 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006744///ubiquinone biosynthetic process+++GO:0016310///phosphorylation+++GO:0021692///cerebellar Purkinje cell layer morphogenesis 76890 76890 'Memo1' mRNA 656.57 712.52 534.32 17.43 16.95 14.67 29.28 28.82 30.92 16.35 29.67333333 1059.04 1007.52 1081.99 634.47 1049.516667 1.47E-12 0.719187053 GO:0042277///peptide binding GO:0032886///regulation of microtubule-based process 76892 76892 'Rnft1' mRNA 849 978 904 10.28 11.65 11.61 11.07 11.64 12.8 11.18 11.83666667 1052 1081 1178 910.3333333 1103.666667 0.009607215 0.266592648 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane GO:0016740///transferase activity+++GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:1904294///positive regulation of ERAD pathway 76893 76893 'Cers2' mRNA 5782.79 5838.72 5710 155.38 154.37 162.61 171.32 175.27 170.27 157.4533333 172.2866667 7333 7320 7051 5777.17 7234.666667 3.27E-08 0.312520969 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0048681///negative regulation of axon regeneration+++GO:1900148///negative regulation of Schwann cell migration+++GO:1905045///negative regulation of Schwann cell proliferation involved in axon regeneration 76894 76894 'Mettl15' mRNA 253 261 236 7.12 7.24 7.29 4 4.17 4.62 7.216666667 4.263333333 168 161 176 250 168.3333333 8.47E-04 -0.581214394 GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0071424///rRNA (cytosine-N4-)-methyltransferase activity GO:0032259///methylation+++GO:0070475///rRNA base methylation 76895 76895 'Bicd2' mRNA 789 867 659 7.66 8.39 6.66 9.55 8.71 9.42 7.57 9.226666667 1043 896 991 771.6666667 976.6666667 0.001795494 0.331484582 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005642///annulate lamellae+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0031267///small GTPase binding+++GO:0034452///dynactin binding+++GO:0051959///dynein light intermediate chain binding+++GO:0070840///dynein complex binding "GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007018///microtubule-based movement+++GO:0015031///protein transport+++GO:0033365///protein localization to organelle+++GO:0034067///protein localization to Golgi apparatus+++GO:0051028///mRNA transport+++GO:0051642///centrosome localization+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0072385///minus-end-directed organelle transport along microtubule+++GO:0072393///microtubule anchoring at microtubule organizing center" 76897 76897 'Ralyl' mRNA 973.32 983.22 890.09 17.01 17.03 17.25 2.3 2.45 2.62 17.09666667 2.456666667 139.77 142.42 136.69 948.8766667 139.6266667 2.05E-115 -2.781141396 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding GO:0008150///biological_process 76898 76898 'B3gat1' mRNA 7 9 4 0.11 0.1 0.07 0 0 0.03 0.093333333 0.01 0 0 4 6.666666667 1.333333333 0.149509944 -2.315165829 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0015018///galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process+++GO:0071456///cellular response to hypoxia 76899 76899 'Golga1' mRNA 1072 1186 1045 11.71 12.75 12.11 7.15 6.12 6.77 12.19 6.68 763 632 690 1101 695 2.31E-12 -0.675605467 GO:0001669///acrosomal vesicle+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm GO:0005515///protein binding GO:0008150///biological_process 76900 76900 'Ssbp4' mRNA 1970 1944 845 77.92 76.1 35.38 66.61 112.58 85.48 63.13333333 88.22333333 1924 3185 2405 1586.333333 2504.666667 0.158124079 0.670354296 GO:0005634///nucleus GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding GO:0045944///positive regulation of transcription by RNA polymerase II 76901 76901 'Jade2' mRNA 614 592 495 5.34 5.08 4.58 3.61 3.21 3.33 5 3.383333333 476 410 426 567 437.3333333 0.002008537 -0.384128223 GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043966///histone H3 acetylation+++GO:0043981///histone H4-K5 acetylation+++GO:0043982///histone H4-K8 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0050767///regulation of neurogenesis+++GO:0050769///positive regulation of neurogenesis+++GO:0051865///protein autoubiquitination+++GO:0060395///SMAD protein signal transduction+++GO:1990138///neuron projection extension 76905 76905 'Lrg1' mRNA 610 646 622 27.09 28.31 29.3 30.86 32.7 30.47 28.23333333 31.34333333 798 825 762 626 795 0.001688926 0.333065991 GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle GO:0005160///transforming growth factor beta receptor binding GO:0001938///positive regulation of endothelial cell proliferation+++GO:0009617///response to bacterium+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0050873///brown fat cell differentiation 76915 76915 'Mnd1' mRNA 34 23 22 2.58 1.73 1.79 2.25 1.98 2.19 2.033333333 2.14 34 28 32 26.33333333 31.33333333 0.69115348 0.240998349 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding GO:0006310///DNA recombination+++GO:0007131///reciprocal meiotic recombination+++GO:0051321///meiotic cell cycle 76916 76916 'Timmdc1' mRNA 633 587.05 653 18.3 16.07 19.76 16.43 15.55 15.41 18.04333333 15.79666667 661 626 613 624.35 633.3333333 0.97292398 0.006030663 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0008150///biological_process 76917 76917 'Flywch2' mRNA 939 875 863 101.35 93.46 98.78 33.51 42.66 37.4 97.86333333 37.85666667 351 432 379 892.3333333 387.3333333 1.40E-25 -1.214027741 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76925 76925 'Spata46' mRNA 40 43 45 3.68 3.93 4.39 0.88 0.41 0.5 4 0.596666667 11 5 6 42.66666667 7.333333333 3.95E-06 -2.559044182 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031965///nuclear membrane GO:0003674///molecular_function GO:0007283///spermatogenesis+++GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0009566///fertilization+++GO:0030154///cell differentiation 76927 76927 'Tsacc' mRNA 42 37 55 5.65 5.08 7.79 5.71 5.23 5.94 6.173333333 5.626666667 48 43 48 44.66666667 46.33333333 0.949663497 0.032536469 GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0051087///chaperone binding GO:0043086///negative regulation of catalytic activity+++GO:0045860///positive regulation of protein kinase activity 76932 76932 'Arfip2' mRNA 1369 1354 1225 22.83 22.23 21.69 19.74 20.07 19.3 22.25 19.70333333 1362 1352 1287 1316 1333.666667 0.933512103 0.009003173 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0032588///trans-Golgi network membrane GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019904///protein domain specific binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0140090///membrane curvature sensor activity GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0030036///actin cytoskeleton organization+++GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation 76933 76933 'Ifi27l2a' mRNA 8562 8406 9360 1649.09 1621.41 1912.89 2731.48 3120 3046.7 1727.796667 2966.06 16116 17844 17270 8776 17076.66667 6.70E-36 0.946110317 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function+++GO:0005521///lamin binding+++GO:0042802///identical protein binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0007568///aging+++GO:0009615///response to virus+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0044827///modulation by host of viral genome replication+++GO:0045087///innate immune response+++GO:0046825///regulation of protein export from nucleus+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0070936///protein K48-linked ubiquitination+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway 76936 76936 'Hnrnpm' mRNA 2673 2839 2579 60.25 63.03 61.69 65.36 62.81 60.71 61.65666667 62.96 3328 3118 2984 2697 3143.333333 0.001809534 0.20948235 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016363///nuclear matrix+++GO:0042382///paraspeckles+++GO:0062023///collagen-containing extracellular matrix+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0048306///calcium-dependent protein binding+++GO:1990405///protein antigen binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1904591///positive regulation of protein import+++GO:2000815///regulation of mRNA stability involved in response to oxidative stress" 76938 76938 'Rbm17' mRNA 1238 1324 1300 47.53 50.13 52.95 51.1 52.06 52.13 50.20333333 51.76333333 1529 1520 1509 1287.333333 1519.333333 0.007981769 0.226499511 03040///Spliceosome GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0032991///protein-containing complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0045292///mRNA cis splicing, via spliceosome" 76942 76942 'Lypd5' mRNA 3 1 0 0.13 0.04 0 0 0.04 0 0.056666667 0.013333333 0 1 0 1.333333333 0.333333333 0.613640626 -1.878270324 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane GO:0043236///laminin binding GO:0007160///cell-matrix adhesion 76943 76943 'Psapl1' mRNA 49 43 33 1.07 0.92 0.76 0.57 0.49 0.65 0.916666667 0.57 30 25 33 41.66666667 29.33333333 0.275531168 -0.513377604 00600///Sphingolipid metabolism+++04142///Lysosome GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005829///cytosol GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0019216///regulation of lipid metabolic process+++GO:0060736///prostate gland growth+++GO:0060742///epithelial cell differentiation involved in prostate gland development 76947 76947 'Ndufaf6' mRNA 219.85 249.94 224.71 9.65 11.56 10.58 11.85 10.5 11.45 10.59666667 11.26666667 260.83 244.4 251.82 231.5 252.35 0.573651079 0.114237006 04714///Thermogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0016740///transferase activity GO:0009058///biosynthetic process+++GO:0032981///mitochondrial respiratory chain complex I assembly 76952 76952 'Nt5c2' mRNA 2822.8 2961.48 2569 32.71 33.97 32.08 23.46 22.22 24.24 32.92 23.30666667 2273 2090 2237 2784.426667 2200 1.04E-07 -0.349863278 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0008253///5'-nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050483///IMP 5'-nucleotidase activity+++GO:0050484///GMP 5'-nucleotidase activity GO:0000255///allantoin metabolic process+++GO:0006202///GMP catabolic process to guanine+++GO:0006204///IMP catabolic process+++GO:0008152///metabolic process+++GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation+++GO:0046038///GMP catabolic process+++GO:0046040///IMP metabolic process+++GO:0046055///dGMP catabolic process+++GO:0046085///adenosine metabolic process 76954 76954 'Denn2b' mRNA 3192.55 3229.03 3038.14 37.63 37.45 38.4 25.07 26.77 24.59 37.82666667 25.47666667 2490.54 2556.67 2325.9 3153.24 2457.703333 3.36E-08 -0.37089061 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0055037///recycling endosome GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 76959 76959 'Chmp5' mRNA 2807 2742 2655 122.63 118.21 123.06 129.31 123.15 124.73 121.3 125.73 3399 3158 3171 2734.666667 3242.666667 2.67E-04 0.233610467 04144///Endocytosis+++04217///Necroptosis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0001919///regulation of receptor recycling+++GO:0006900///vesicle budding from membrane+++GO:0006997///nucleus organization+++GO:0007034///vacuolar transport+++GO:0007040///lysosome organization+++GO:0007080///mitotic metaphase plate congression+++GO:0008333///endosome to lysosome transport+++GO:0010824///regulation of centrosome duplication+++GO:0015031///protein transport+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0046755///viral budding+++GO:0061763///multivesicular body-lysosome fusion+++GO:0061952///midbody abscission+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071225///cellular response to muramyl dipeptide+++GO:0071985///multivesicular body sorting pathway+++GO:1901673///regulation of mitotic spindle assembly 76960 76960 'Bcas1' mRNA 1063 1011 1165 18.51 17.25 21.51 12.46 15.15 13.62 19.09 13.74333333 818 969 858 1079.666667 881.6666667 0.010211228 -0.306368863 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density GO:0042803///protein homodimerization activity GO:0042552///myelination 76964 76964 '2610028H24Rik' mRNA 14.64 9.04 10.59 0.52 0.31 0.58 0.05 0.31 0.15 0.47 0.17 1 10.47 3 11.42333333 4.823333333 0.259305645 -1.235324969 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 76965 76965 'Slitrk1' mRNA 10 7 9 0.13 0.09 0.12 0.05 0.07 0.1 0.113333333 0.073333333 5 6 9 8.666666667 6.666666667 0.741194687 -0.390862479 GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0003674///molecular_function GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0007416///synapse assembly+++GO:0030534///adult behavior+++GO:0035264///multicellular organism growth+++GO:0042592///homeostatic process+++GO:0050772///positive regulation of axonogenesis+++GO:0050807///regulation of synapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:0099560///synaptic membrane adhesion+++GO:1905606///regulation of presynapse assembly 76967 76967 '2700049A03Rik' mRNA 512 523 485 5.66 5.79 5.85 3.49 3.21 3.65 5.766666667 3.45 357 321 357 506.6666667 345 5.52E-06 -0.565997921 GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly+++GO:0070201///regulation of establishment of protein localization 76969 76969 'Chst1' mRNA 18 28 9 0.41 0.66 0.23 1.58 1.59 1.35 0.433333333 1.506666667 77 77 63 18.33333333 72.33333333 2.45E-06 1.981550209 00533///Glycosaminoglycan biosynthesis - keratan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0045130///keratan sulfotransferase activity GO:0005975///carbohydrate metabolic process+++GO:0006012///galactose metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006790///sulfur compound metabolic process+++GO:0006954///inflammatory response+++GO:0042339///keratan sulfate metabolic process 76974 76974 'Urah' mRNA 114 131 106 11.31 14.47 11.73 19 15.98 16.8 12.50333333 17.26 195 168 173 117 178.6666667 0.004417038 0.600434456 00230///Purine metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005777///peroxisome GO:0005179///hormone activity+++GO:0016787///hydrolase activity+++GO:0033971///hydroxyisourate hydrolase activity+++GO:0051997///2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity+++GO:0070324///thyroid hormone binding GO:0000255///allantoin metabolic process+++GO:0006144///purine nucleobase metabolic process+++GO:0006147///guanine catabolic process+++GO:0006148///inosine catabolic process+++GO:0006149///deoxyinosine catabolic process+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process+++GO:0006161///deoxyguanosine catabolic process+++GO:0006196///AMP catabolic process+++GO:0006204///IMP catabolic process+++GO:0007165///signal transduction+++GO:0009114///hypoxanthine catabolic process+++GO:0009115///xanthine catabolic process+++GO:0019628///urate catabolic process+++GO:0046038///GMP catabolic process+++GO:0046055///dGMP catabolic process+++GO:0046059///dAMP catabolic process 76976 76976 'Arxes2' mRNA 1520.58 1557.49 1609.11 58.12 58.71 65.25 31.29 30.45 28.18 60.69333333 29.97333333 940.4 893.2 819.49 1562.393333 884.3633333 1.83E-20 -0.835443223 03060///Protein export GO:0005783///endoplasmic reticulum+++GO:0005787///signal peptidase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0008233///peptidase activity+++GO:0016787///hydrolase activity GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0019082///viral protein processing+++GO:0045047///protein targeting to ER+++GO:0045444///fat cell differentiation 76980 76980 'Ube2ql1' mRNA 270 308 297 5.58 6.26 6.51 0.7 0.79 0.89 6.116666667 0.793333333 39 43 48 291.6666667 43.33333333 4.11E-37 -2.762964797 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination 76982 76982 'Vxn' mRNA 5 6 5 0.09 0.1 0.09 0.33 0.31 0.26 0.093333333 0.3 22 20 17 5.333333333 19.66666667 0.012489791 1.871428711 GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation 76983 76983 'Scfd1' mRNA 1307 1425 1310 32.83 35.33 35.02 38.64 38.37 39.85 34.39333333 38.95333333 1756 1696 1740 1347.333333 1730.666667 5.09E-06 0.349801365 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005798///Golgi-associated vesicle+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane GO:0019905///syntaxin binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding "GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0009636///response to toxic substance+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051223///regulation of protein transport+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:1901998///toxin transport+++GO:1902902///negative regulation of autophagosome assembly" 76987 76987 'Hdhd2' mRNA 1043 1009 1051 26.63 25.23 28.07 21.34 18.79 21.52 26.64333333 20.55 979 858 931 1034.333333 922.6666667 0.081298866 -0.178916122 GO:0016791///phosphatase activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding GO:0016311///dephosphorylation 76998 76998 'Fbxw27' mRNA 0 1 0 0 0.04 0 0 0 0 0.013333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77006 77006 'Ddrgk1' mRNA 1937 1990 2013 110 111.67 121.29 84.16 93.68 88.95 114.32 88.93 1700 1845 1737 1980 1760.666667 0.036013377 -0.181678747 GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0005515///protein binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0008284///positive regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030335///positive regulation of cell migration+++GO:0031647///regulation of protein stability+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051216///cartilage development+++GO:0061709///reticulophagy+++GO:0070972///protein localization to endoplasmic reticulum+++GO:0071569///protein ufmylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:1903895///negative regulation of IRE1-mediated unfolded protein response+++GO:1905050///positive regulation of metallopeptidase activity+++GO:1905552///positive regulation of protein localization to endoplasmic reticulum+++GO:1905636///positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:1990592///protein K69-linked ufmylation 77011 77011 'Ticrr' mRNA 7 1 0 0.05 0.01 0 0.29 0.27 0.35 0.02 0.303333333 45 41 53 2.666666667 46.33333333 2.08E-08 4.117074148 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007165///signal transduction+++GO:0010212///response to ionizing radiation+++GO:0016310///phosphorylation+++GO:0030174///regulation of DNA-dependent DNA replication initiation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0036035///osteoclast development+++GO:0045453///bone resorption+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1902533///positive regulation of intracellular signal transduction 77015 77015 'Mpped2' mRNA 757 700 617 15.13 14.02 13.12 10.31 7.98 9.01 14.09 9.1 597 465 524 691.3333333 528.6666667 0.001071188 -0.398052056 GO:0005575///cellular_component GO:0000166///nucleotide binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016208///AMP binding+++GO:0016787///hydrolase activity+++GO:0019002///GMP binding+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 77018 77018 'Col25a1' mRNA 150 199 139 1.04 1.37 1.05 0.19 0.16 0.15 1.153333333 0.166666667 29 25 24 162.6666667 26 3.52E-20 -2.652810658 04974///Protein digestion and absorption GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0001540///amyloid-beta binding+++GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0042802///identical protein binding GO:0030198///extracellular matrix organization+++GO:0060385///axonogenesis involved in innervation 77031 77031 'Slc9a8' mRNA 1014 1008.82 848.99 10.81 10.73 9.71 6.92 6.84 6.3 10.41666667 6.686666667 752 728 649 957.27 709.6666667 1.48E-05 -0.439928313 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH+++GO:0035725///sodium ion transmembrane transport+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902600///proton transmembrane transport 77032 77032 'Tstd3' mRNA 191.5 170.7 208.53 7.07 6.22 8.17 7.1 9.35 7.3 7.153333333 7.916666667 220.74 283.81 219.62 190.2433333 241.39 0.121528507 0.329795908 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0004792///thiosulfate sulfurtransferase activity GO:0008150///biological_process 77034 77034 '2510039O18Rik' mRNA 362 379 263 7.22 7.42 5.58 6.95 7.19 6.96 6.74 7.033333333 401 404 390 334.6666667 398.3333333 0.126706432 0.24604166 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77035 77035 'Kdm8' mRNA 155 207 163 3.16 4.22 3.48 2.23 2.2 2.88 3.62 2.436666667 124 115 157 175 132 0.077370827 -0.416006932 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol "GO:0003674///molecular_function+++GO:0003682///chromatin binding+++GO:0004175///endopeptidase activity+++GO:0004177///aminopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016491///oxidoreductase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0016787///hydrolase activity+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0051864///histone demethylase activity (H3-K36 specific)" "GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006508///proteolysis+++GO:0007049///cell cycle+++GO:0031648///protein destabilization+++GO:0032922///circadian regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0070544///histone H3-K36 demethylation" 77037 77037 'Mrap' mRNA 194 186 190 10.81 10.24 11.24 16.86 16.64 17.14 10.76333333 16.88 347 334 341 190 340.6666667 6.44E-08 0.829906501 04927///Cortisol synthesis and secretion+++04934///Cushing syndrome GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0030545///receptor regulator activity+++GO:0031780///corticotropin hormone receptor binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0031783///type 5 melanocortin receptor binding+++GO:0042802///identical protein binding+++GO:0070996///type 1 melanocortin receptor binding GO:0050873///brown fat cell differentiation+++GO:0072659///protein localization to plasma membrane+++GO:0106070///regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0106071///positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1903077///negative regulation of protein localization to plasma membrane 77038 77038 'Arfgap2' mRNA 2010.48 2360.97 2169.54 32.54 37.58 37.22 32.95 32.11 34.69 35.78 33.25 2344.36 2230.79 2389.3 2180.33 2321.483333 0.403587203 0.078507061 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0048205///COPI coating of Golgi vesicle+++GO:0050790///regulation of catalytic activity 77040 77040 'Atg16l1' mRNA 559 606 616 10.08 10.62 11.6 11.82 10.58 10.47 10.76666667 10.95666667 764 672 654 593.6666667 696.6666667 0.079390078 0.216193087 04136///Autophagy - other+++04140///Autophagy - animal+++04621///NOD-like receptor signaling pathway+++05131///Shigellosis GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0034045///phagophore assembly site membrane+++GO:0120095///vacuole-isolation membrane contact site GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0051020///GTPase binding GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0010508///positive regulation of autophagy+++GO:0015031///protein transport+++GO:0034497///protein localization to phagophore assembly site+++GO:0039689///negative stranded viral RNA replication+++GO:0061739///protein lipidation involved in autophagosome assembly+++GO:0098792///xenophagy 77041 77041 'Arsk' mRNA 499 539 537 7.61 8.06 8.71 7.63 6.57 7.8 8.126666667 7.333333333 569 489 565 525 541 0.863090843 0.029400009 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005764///lysosome GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0015024///glucuronate-2-sulfatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding 77044 77044 'Arid2' mRNA 1117 1151 1001 6.49 6.57 6.17 4.8 4.58 4.9 6.41 4.76 951 888 941 1089.666667 926.6666667 0.006903397 -0.243815271 05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005886///plasma membrane+++GO:0070603///SWI/SNF superfamily-type complex GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding "GO:0003007///heart morphogenesis+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008285///negative regulation of cell proliferation+++GO:0030336///negative regulation of cell migration+++GO:0042592///homeostatic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048568///embryonic organ development+++GO:0060038///cardiac muscle cell proliferation+++GO:0060982///coronary artery morphogenesis+++GO:0072359///circulatory system development+++GO:1905168///positive regulation of double-strand break repair via homologous recombination" 77045 77045 'Bcl7a' mRNA 670 712 458 9.52 9.95 6.9 2.9 2.87 3.03 8.79 2.933333333 235 227 238 613.3333333 233.3333333 1.59E-20 -1.397594832 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77048 77048 'Cep83' mRNA 152 162 68 2.8 2.93 1.33 2.3 4.18 3.6 2.353333333 3.36 144 255 218 127.3333333 205.6666667 0.020302733 0.701172979 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0097539///ciliary transition fiber GO:0003674///molecular_function+++GO:0042802///identical protein binding GO:0030030///cell projection organization+++GO:0048278///vesicle docking+++GO:0051660///establishment of centrosome localization+++GO:0060271///cilium assembly+++GO:0071539///protein localization to centrosome 77053 77053 'Sun1' mRNA 2280.03 2504.84 2454.99 32.79 35.4 37.1 21.38 20.63 21.58 35.09666667 21.19666667 1726.75 1621.29 1702.69 2413.286667 1683.576667 2.62E-12 -0.532930493 GO:0002080///acrosomal membrane+++GO:0002081///outer acrosomal membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005639///integral component of nuclear inner membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0043495///protein membrane anchor GO:0001503///ossification+++GO:0006998///nuclear envelope organization+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0009612///response to mechanical stimulus+++GO:0021817///nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration+++GO:0030154///cell differentiation+++GO:0051321///meiotic cell cycle+++GO:0051642///centrosome localization+++GO:0070197///meiotic attachment of telomere to nuclear envelope+++GO:0090292///nuclear matrix anchoring at nuclear membrane 77056 77056 'Tmco4' mRNA 424 401 424 6.78 6.34 7.55 6.41 6.08 6.58 6.89 6.356666667 445 406 444 416.3333333 431.6666667 0.836000484 0.038542763 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77057 77057 'Ston1' mRNA 386.95 323.12 319.05 4.64 3.92 4.13 4.08 3.86 4.57 4.23 4.17 399 352 413 343.04 388 0.307729062 0.167874883 GO:0005737///cytoplasm+++GO:0005905///clathrin-coated pit+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031252///cell leading edge+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0035615///clathrin adaptor activity GO:0006897///endocytosis+++GO:0006929///substrate-dependent cell migration+++GO:0016192///vesicle-mediated transport+++GO:0030100///regulation of endocytosis+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048041///focal adhesion assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:0097178///ruffle assembly+++GO:0120181///focal adhesion disassembly 77065 77065 'Ints7' mRNA 560.81 634.92 600.98 5.61 6.23 6.35 5.06 5.11 5.18 6.063333333 5.116666667 585.03 577.19 580.26 598.9033333 580.8266667 0.720819007 -0.054602459 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0032039///integrator complex GO:0003674///molecular_function GO:0000077///DNA damage checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016180///snRNA processing+++GO:0034472///snRNA 3'-end processing+++GO:0071479///cellular response to ionizing radiation 77087 77087 'Ankrd11' mRNA 1677 1615 1470 9.98 9.41 9.35 9.08 8.4 9.02 9.58 8.833333333 1753 1567 1674 1587.333333 1664.666667 0.542716156 0.057719944 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0001894///tissue homeostasis+++GO:0009653///anatomical structure morphogenesis+++GO:0035264///multicellular organism growth+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0048705///skeletal system morphogenesis+++GO:0060323///head morphogenesis+++GO:0060325///face morphogenesis+++GO:0060348///bone development 77090 77090 'Ocel1' mRNA 251 281 258 9.12 10.14 9.9 14.09 12.52 12.61 9.72 13.07333333 446 389 387 263.3333333 407.3333333 1.49E-05 0.616786521 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77097 77097 'Tanc2' mRNA 848 1038 796 3.7 4.45 3.67 2.36 2.09 2.16 3.94 2.203333333 628 542 552 894 574 6.87E-09 -0.64849357 "GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component" GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0060998///regulation of dendritic spine development+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0099519///dense core granule cytoskeletal transport 77106 77106 'Tmem181a' mRNA 869.43 830.78 920.5 15.27 15.97 18.1 18.29 18.48 17.73 16.44666667 18.16666667 1117.31 1084.54 1063.88 873.57 1088.576667 0.002802772 0.303008386 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015643///toxic substance binding GO:0009405///pathogenesis 77110 77110 'Gpbp1l1' mRNA 919 813 547 13.83 12.12 8.78 10.37 8.23 9.64 11.57666667 9.413333333 786 613 710 759.6666667 703 0.519069321 -0.116632537 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003677///DNA binding+++GO:0003723///RNA binding "GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated" 77113 77113 'Klhl2' mRNA 104 85 94 1.79 1.44 1.71 1.98 1.4 2.84 1.646666667 2.073333333 132 95 179 94.33333333 135.3333333 0.083962158 0.50664001 GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0016567///protein ubiquitination 77116 77116 'Mtmr2' mRNA 1277.66 1347.26 1384.3 16.51 16.97 18.73 22.24 23.49 22.24 17.40333333 22.65666667 1948.08 2021.81 1873.69 1336.406667 1947.86 3.09E-10 0.530331326 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005774///vacuolar membrane+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0097060///synaptic membrane "GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0042802///identical protein binding+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity+++GO:0052866///phosphatidylinositol phosphate phosphatase activity" GO:0002091///negative regulation of receptor internalization+++GO:0006629///lipid metabolic process+++GO:0016311///dephosphorylation+++GO:0031642///negative regulation of myelination+++GO:0032288///myelin assembly+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045806///negative regulation of endocytosis+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046855///inositol phosphate dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0048666///neuron development+++GO:0060304///regulation of phosphatidylinositol dephosphorylation+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0097062///dendritic spine maintenance+++GO:2000643///positive regulation of early endosome to late endosome transport+++GO:2000645///negative regulation of receptor catabolic process 77117 77117 'Zfp934' mRNA 85.56 97.94 100.02 2.16 2.49 2.75 2.27 1.46 1.95 2.466666667 1.893333333 103.59 63.86 86.69 94.50666667 84.71333333 0.613640626 -0.179909327 GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 77125 77125 'Il33' mRNA 728 700 683 15.91 15.04 15.84 26.47 27.45 27.73 15.59666667 27.21666667 1391 1409 1410 703.6666667 1403.333333 7.04E-31 0.984659781 04060///Cytokine-cytokine receptor interaction+++04217///Necroptosis+++04623///Cytosolic DNA-sensing pathway+++05164///Influenza A GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0002112///interleukin-33 receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001819///positive regulation of cytokine production+++GO:0002281///macrophage activation involved in immune response+++GO:0002282///microglial cell activation involved in immune response+++GO:0002638///negative regulation of immunoglobulin production+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002686///negative regulation of leukocyte migration+++GO:0002826///negative regulation of T-helper 1 type immune response+++GO:0002830///positive regulation of type 2 immune response+++GO:0007165///signal transduction+++GO:0010186///positive regulation of cellular defense response+++GO:0010628///positive regulation of gene expression+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032722///positive regulation of chemokine production+++GO:0032736///positive regulation of interleukin-13 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0038172///interleukin-33-mediated signaling pathway+++GO:0043032///positive regulation of macrophage activation+++GO:0045345///positive regulation of MHC class I biosynthetic process+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0051607///defense response to virus+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0051930///regulation of sensory perception of pain+++GO:0061518///microglial cell proliferation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0120042///negative regulation of macrophage proliferation 77128 77128 'Crebrf' mRNA 1849 1795 1653 13.12 12.49 12.43 8.33 7.05 7.81 12.68 7.73 1356 1123 1229 1765.666667 1236 1.08E-10 -0.526427214 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0032388///positive regulation of intracellular transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042711///maternal behavior+++GO:0045732///positive regulation of protein catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051222///positive regulation of protein transport+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:1900170///negative regulation of glucocorticoid mediated signaling pathway+++GO:1902213///positive regulation of prolactin signaling pathway" 77134 77134 'Hnrnpa0' mRNA 553 477 435 11.44 9.71 9.55 12.23 8.51 10.07 10.23333333 10.27 680 462 542 488.3333333 561.3333333 0.24947026 0.188360625 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0019901///protein kinase binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding GO:0006954///inflammatory response+++GO:0032496///response to lipopolysaccharide+++GO:0070935///3'-UTR-mediated mRNA stabilization 77200 77200 '5430403G16Rik' mRNA 289.11 252.3 284.22 5.05 4.34 5.26 2.52 1.97 2.18 4.883333333 2.223333333 166.15 126.61 139 275.21 143.92 2.33E-07 -0.952731027 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 77219 77219 'Ptgr2' mRNA 1533 1638 1649 27.03 28.46 30.84 27.5 25.11 27.99 28.77666667 26.86666667 1793 1603 1770 1606.666667 1722 0.385017708 0.085968246 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol "GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0036132///13-prostaglandin reductase activity+++GO:0047522///15-oxoprostaglandin 13-oxidase activity" GO:0006693///prostaglandin metabolic process 77220 77220 'Tmem200a' mRNA 455 450 390 6.44 6.22 5.83 0.75 0.87 0.8 6.163333333 0.806666667 58 63 59 431.6666667 60 1.95E-57 -2.855805836 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77252 77252 '9430038I01Rik' mRNA 77.02 87.01 76.98 3.18 3.86 4.07 6.35 5.56 6.39 3.703333333 6.1 154.58 131.01 158 80.33666667 147.8633333 2.25E-04 0.872884542 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77254 77254 'Yif1b' mRNA 2014.59 1961 2001.99 108.65 104.17 114.06 92.32 100.61 94.75 108.96 95.89333333 1969 2089 1958 1992.526667 2005.333333 0.986670256 -0.0026096 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030173///integral component of Golgi membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane GO:0003674///molecular_function GO:0006612///protein targeting to membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007288///sperm axoneme assembly+++GO:0015031///protein transport 77264 77264 'Zfp142' mRNA 650 650 697 5.46 5.41 6.32 4.41 4.19 4.05 5.73 4.216666667 604 554 532 665.6666667 563.3333333 0.035789375 -0.25564627 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II 77286 77286 'Nkrf' mRNA 53 44 39 0.52 0.43 0.41 0.54 0.58 0.43 0.453333333 0.516666667 63 66 49 45.33333333 59.33333333 0.342586551 0.379612095 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding" "GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 77300 77300 'Raph1' mRNA 1556 1427 1133 13.13 12.03 10.87 4.53 5.17 5.46 12.01 5.053333333 682 663 731 1372 692 8.32E-22 -0.993919211 04361///Axon regeneration GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0031252///cell leading edge GO:0005515///protein binding GO:0007165///signal transduction+++GO:0048675///axon extension 77305 77305 'Wdr82' mRNA 411 342 325 5.7 4.77 4.71 5.97 5.58 6.06 5.06 5.87 488 451 477 359.3333333 472 0.005342099 0.383079393 03015///mRNA surveillance pathway "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0035097///histone methyltransferase complex+++GO:0048188///Set1C/COMPASS complex+++GO:0072357///PTW/PP1 phosphatase complex" GO:0003682///chromatin binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific) GO:0051568///histone H3-K4 methylation+++GO:0080182///histone H3-K4 trimethylation 77318 77318 'Ankrd55' mRNA 67.95 44.27 44.78 0.69 0.45 0.51 0.54 0.59 0.69 0.55 0.606666667 55.93 43 59.04 52.33333333 52.65666667 0.99331619 0.008226684 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77352 77352 'Axdnd1' mRNA 6 4 6 0.09 0.06 0.1 0.08 0.05 0.01 0.083333333 0.046666667 6 4 1 5.333333333 3.666666667 0.720293678 -0.563696589 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77358 77358 '9430069I07Rik' mRNA 1 0 0 0.14 0 0 0.36 0 0 0.046666667 0.12 3 0 0 0.333333333 1 0.755726907 1.439428941 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77371 77371 'Sec24a' mRNA 741.07 655 520.21 6.23 5.25 4.57 6.25 5.33 5.88 5.35 5.82 909.01 742.06 817 638.76 822.69 0.004479947 0.357027089 04141///Protein processing in endoplasmic reticulum+++05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0070971///endoplasmic reticulum exit site GO:0000149///SNARE binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0032374///regulation of cholesterol transport+++GO:0042632///cholesterol homeostasis+++GO:0050714///positive regulation of protein secretion+++GO:0090110///cargo loading into COPII-coated vesicle 77407 77407 'Rab35' mRNA 143 141 98 3.73 3.63 2.71 4.4 4.37 4.97 3.356666667 4.58 194 188 212 127.3333333 198 0.002808911 0.631531079 04144///Endocytosis GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031253///cell projection membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042470///melanosome+++GO:0045171///intercellular bridge+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0098993///anchored component of synaptic vesicle membrane "GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019003///GDP binding" GO:0000281///mitotic cytokinesis+++GO:0008104///protein localization+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0019882///antigen processing and presentation+++GO:0031175///neuron projection development+++GO:0032456///endocytic recycling+++GO:0032482///Rab protein signal transduction+++GO:0036010///protein localization to endosome+++GO:0048227///plasma membrane to endosome transport+++GO:1990090///cellular response to nerve growth factor stimulus 77411 77411 'Esrp2' mRNA 149.96 126.21 152.8 2.63 2.11 2.8 3.72 3.41 2.81 2.513333333 3.313333333 246 215.07 175.62 142.99 212.23 0.009357707 0.55827661 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060445///branching involved in salivary gland morphogenesis" 77422 77422 'C330018D20Rik' mRNA 268 256 266 6.2 6.62 7.22 7.5 5.99 6.31 6.68 6.6 308 269 254 263.3333333 277 0.78666572 0.058954419 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0008150///biological_process 77446 77446 'Heg1' mRNA 564 576 378 3.32 3.45 2.57 7.65 7.76 8.3 3.113333333 7.903333333 1385 1455 1522 506 1454 1.84E-38 1.519591626 GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0001570///vasculogenesis+++GO:0001701///in utero embryonic development+++GO:0001885///endothelial cell development+++GO:0001886///endothelial cell morphogenesis+++GO:0001944///vasculature development+++GO:0001945///lymph vessel development+++GO:0003017///lymph circulation+++GO:0003209///cardiac atrium morphogenesis+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003281///ventricular septum development+++GO:0007043///cell-cell junction assembly+++GO:0007275///multicellular organism development+++GO:0007507///heart development+++GO:0009791///post-embryonic development+++GO:0030324///lung development+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0035264///multicellular organism growth+++GO:0045216///cell-cell junction organization+++GO:0048845///venous blood vessel morphogenesis+++GO:0050878///regulation of body fluid levels+++GO:0055017///cardiac muscle tissue growth+++GO:0060039///pericardium development+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:1902414///protein localization to cell junction+++GO:1905709///negative regulation of membrane permeability+++GO:2000299///negative regulation of Rho-dependent protein serine/threonine kinase activity 77462 77462 'Tmem116' mRNA 68 80 75 2.93 3.62 3.4 3.29 3.5 3.96 3.316666667 3.583333333 85 89 98 74.33333333 90.66666667 0.388672197 0.275156782 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 77480 77480 'Kidins220' mRNA 2639 2725 2496 19.8 19.99 19.93 17.78 15.05 17.33 19.90666667 16.72 2715 2272 2554 2620 2513.666667 0.402755322 -0.071964613 04722///Neurotrophin signaling pathway GO:0005770///late endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex GO:0019887///protein kinase regulator activity+++GO:0019901///protein kinase binding+++GO:0030165///PDZ domain binding GO:0001701///in utero embryonic development+++GO:0010976///positive regulation of neuron projection development+++GO:0038180///nerve growth factor signaling pathway+++GO:0048813///dendrite morphogenesis+++GO:0050790///regulation of catalytic activity+++GO:1990090///cellular response to nerve growth factor stimulus 77485 77485 'Stk31' mRNA 0 1 0 0 0.02 0 0 0 0.02 0.006666667 0.006666667 0 0 1 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004518///nuclease activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 77505 77505 'Dnhd1' mRNA 219 215 160 0.78 0.75 0.61 0.45 0.45 0.4 0.713333333 0.433333333 144 143 124 198 137 0.009900578 -0.537771192 GO:0030286///dynein complex+++GO:0036156///inner dynein arm "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding" GO:0003341///cilium movement+++GO:0007018///microtubule-based movement 77519 77519 'Zfp266' mRNA 1490 1482 1522 12.57 12.3 13.63 9.99 9.6 9.93 12.83333333 9.84 1363 1280 1312 1498 1318.333333 0.02204542 -0.197846772 05168///Herpes simplex virus 1 infection "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 77521 77521 'Mtus2' mRNA 2705 2836 2518 21.85 22.18 21.51 4.84 4.67 4.39 21.84666667 4.633333333 491 457 445 2686.333333 464.3333333 1.28E-231 -2.543117283 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule GO:0008017///microtubule binding+++GO:0042803///protein homodimerization activity 77522 77522 'Tmem213' mRNA 4 0 2 0.62 0 0.33 0 0 0.14 0.316666667 0.046666667 0 0 1 2 0.333333333 0.412622832 -2.49962431 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77531 77531 'Anks1b' mRNA 1319.84 1356.98 1161 12.68 12.83 11.96 1.79 1.9 1.93 12.49 1.873333333 210 217 222 1279.273333 216.3333333 1.08E-130 -2.572307846 "GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol" GO:0005515///protein binding+++GO:0046875///ephrin receptor binding "GO:0048013///ephrin receptor signaling pathway+++GO:0097120///receptor localization to synapse+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:0099565///chemical synaptic transmission, postsynaptic+++GO:1900383///regulation of synaptic plasticity by receptor localization to synapse" 77532 77532 'Jrkl' mRNA 128 178 97 2.38 3.26 1.92 2.4 2.3 1.97 2.52 2.223333333 148 139 118 134.3333333 135 0.997052821 0.004153604 GO:0005634///nucleus GO:0003676///nucleic acid binding+++GO:0003677///DNA binding GO:0008150///biological_process 77552 77552 'Shisa4' mRNA 940 848 846 48.59 43.3 46.4 64.64 65.41 65.79 46.09666667 65.28 1435 1416 1412 878 1421 9.46E-16 0.683106204 GO:0016020///membrane+++GO:0016021///integral component of membrane 77559 77559 'Agl' mRNA 842.64 824.87 718.36 7.76 7.84 6.98 6.02 5.8 5.97 7.526666667 5.93 796.75 702.21 737.21 795.29 745.39 0.377010403 -0.103382985 00500///Starch and sucrose metabolism GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016234///inclusion body+++GO:0016529///sarcoplasmic reticulum "GO:0003824///catalytic activity+++GO:0004133///glycogen debranching enzyme activity+++GO:0004134///4-alpha-glucanotransferase activity+++GO:0004135///amylo-alpha-1,6-glucosidase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0030247///polysaccharide binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0102500///beta-maltose 4-alpha-glucanotransferase activity" GO:0005975///carbohydrate metabolic process+++GO:0005977///glycogen metabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0005980///glycogen catabolic process+++GO:0007584///response to nutrient+++GO:0008152///metabolic process+++GO:0009725///response to hormone+++GO:0051384///response to glucocorticoid 77569 77569 'Limch1' mRNA 1492 1301 1038 13.19 11.27 9.69 7.44 4.94 6.85 11.38333333 6.41 970 634 864 1277 822.6666667 2.23E-06 -0.643878715 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016460///myosin II complex GO:0003779///actin binding+++GO:0032034///myosin II head/neck binding+++GO:0046872///metal ion binding GO:0001934///positive regulation of protein phosphorylation+++GO:0030336///negative regulation of cell migration+++GO:0031032///actomyosin structure organization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051893///regulation of focal adhesion assembly+++GO:0060327///cytoplasmic actin-based contraction involved in cell motility 77573 77573 'Vps33a' mRNA 897 929 814 12.71 13.09 12.06 15.81 14.7 12.34 12.62 14.28333333 1165 1126 943 880 1078 0.006988455 0.282362258 05132///Salmonella infection GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005773///vacuole+++GO:0005776///autophagosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030897///HOPS complex+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0033263///CORVET complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0071439///clathrin complex GO:0044877///protein-containing complex binding GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0030220///platelet formation+++GO:0032400///melanosome localization+++GO:0032418///lysosome localization+++GO:0035751///regulation of lysosomal lumen pH+++GO:0043473///pigmentation+++GO:0048070///regulation of developmental pigmentation+++GO:0097352///autophagosome maturation 77574 77574 'Tcaf1' mRNA 1572 1621 1565 18.06 18.54 18.73 16.26 14.47 17.51 18.44333333 16.08 1660 1436 1684 1586 1593.333333 0.958463402 -0.006259517 GO:0005886///plasma membrane+++GO:0016020///membrane GO:0044325///ion channel binding GO:0010359///regulation of anion channel activity+++GO:0030336///negative regulation of cell migration+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1901529///positive regulation of anion channel activity 77577 77577 'Spns3' mRNA 63 57 49 2.76 2.33 2.29 0.65 0.74 0.64 2.46 0.676666667 21 20 21 56.33333333 20.66666667 3.47E-04 -1.455388387 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0022857///transmembrane transporter activity GO:0006869///lipid transport+++GO:0055085///transmembrane transport 77578 77578 'Bcl9' mRNA 569 573 426 4.69 4.62 3.65 2.31 2.75 2.21 4.32 2.423333333 322.98 378 296 522.6666667 332.3266667 7.93E-06 -0.659575527 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:1990907///beta-catenin-TCF complex GO:0003713///transcription coactivator activity+++GO:0008013///beta-catenin binding GO:0014908///myotube differentiation involved in skeletal muscle regeneration+++GO:0016055///Wnt signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035914///skeletal muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060070///canonical Wnt signaling pathway 77579 77579 'Myh10' mRNA 625 681 626 4.14 4.47 4.4 4.59 4.31 4.05 4.336666667 4.316666667 785.93 729 682.19 644 732.3733333 0.13514596 0.172814024 04270///Vascular smooth muscle contraction+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005903///brush border+++GO:0005938///cell cortex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030027///lamellipodium+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0031594///neuromuscular junction+++GO:0032154///cleavage furrow+++GO:0042641///actomyosin+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0097513///myosin II filament+++GO:0098871///postsynaptic actin cytoskeleton+++GO:0098978///glutamatergic synapse GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0030898///actin-dependent ATPase activity+++GO:0035613///RNA stem-loop binding+++GO:0042802///identical protein binding+++GO:0043531///ADP binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0051015///actin filament binding "GO:0000281///mitotic cytokinesis+++GO:0001701///in utero embryonic development+++GO:0001764///neuron migration+++GO:0001778///plasma membrane repair+++GO:0003279///cardiac septum development+++GO:0006887///exocytosis+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007097///nuclear migration+++GO:0007155///cell adhesion+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0007512///adult heart development+++GO:0008283///cell proliferation+++GO:0008360///regulation of cell shape+++GO:0021592///fourth ventricle development+++GO:0021670///lateral ventricle development+++GO:0021678///third ventricle development+++GO:0021680///cerebellar Purkinje cell layer development+++GO:0030036///actin cytoskeleton organization+++GO:0030048///actin filament-based movement+++GO:0030239///myofibril assembly+++GO:0031032///actomyosin structure organization+++GO:0031175///neuron projection development+++GO:0035904///aorta development+++GO:0050714///positive regulation of protein secretion+++GO:0050885///neuromuscular process controlling balance+++GO:0051017///actin filament bundle assembly+++GO:0055003///cardiac myofibril assembly+++GO:0055015///ventricular cardiac muscle cell development+++GO:0060041///retina development in camera-type eye+++GO:0060976///coronary vasculature development+++GO:0070650///actin filament bundle distribution+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton" 77582 77582 'Mboat7' mRNA 1928 1850 1796 45.94 43.36 45.48 39.25 36.28 40.22 44.92666667 38.58333333 1898 1711 1880 1858 1829.666667 0.737431661 -0.034340844 00564///Glycerophospholipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0044233///Mitochondria-associated ER Membrane "GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0071617///lysophospholipid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0021591///ventricular system development+++GO:0021819///layer formation in cerebral cortex+++GO:0030258///lipid modification+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0046488///phosphatidylinositol metabolic process+++GO:0090207///regulation of triglyceride metabolic process 77583 77583 'Notum' mRNA 167 207 74 4.52 5.63 2.09 0.88 1.4 1.21 4.08 1.163333333 36 56 48 149.3333333 46.66666667 1.25E-06 -1.667624622 04310///Wnt signaling pathway GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:1990699///palmitoleyl hydrolase activity GO:0006507///GPI anchor release+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030500///regulation of bone mineralization+++GO:0060348///bone development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1990697///protein depalmitoleylation 77590 77590 'Chst15' mRNA 496 496 414 5.38 5.3 4.76 2.73 3.05 2.51 5.146666667 2.763333333 293 314 256 468.6666667 287.6666667 3.38E-07 -0.712376023 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0050656///3'-phosphoadenosine 5'-phosphosulfate binding+++GO:0050659///N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity GO:0019319///hexose biosynthetic process 77591 77591 'Ddx10' mRNA 436 489 442 6.91 7.65 7.4 7.7 7.11 7.24 7.32 7.35 557 502 515 455.6666667 524.6666667 0.143031332 0.191550642 GO:0005634///nucleus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0006364///rRNA processing+++GO:0097065///anterior head development 77593 77593 'Usp45' mRNA 296.98 247.02 256 2.63 2.18 2.44 2.65 2.52 2.67 2.416666667 2.613333333 343 318 299 266.6666667 320 0.134375524 0.252489427 GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0003407///neural retina development+++GO:0006281///DNA repair+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016477///cell migration+++GO:0016579///protein deubiquitination+++GO:0045494///photoreceptor cell maintenance 77595 77595 'Nup210l' mRNA 23 9 25 0.21 0.08 0.24 0.13 0.11 0.15 0.176666667 0.13 16 13 18 19 15.66666667 0.719489813 -0.303829459 03013///Nucleocytoplasmic transport+++05014///Amyotrophic lateral sclerosis GO:0005643///nuclear pore+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007286///spermatid development+++GO:0060009///Sertoli cell development 77596 77596 'Adgrf1' mRNA 16 13 11 0.2 0.17 0.15 0.16 0.01 0.13 0.173333333 0.1 12 1 10 13.33333333 7.666666667 0.414061779 -0.815417599 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007416///synapse assembly+++GO:0007613///memory+++GO:0031175///neuron projection development+++GO:0032793///positive regulation of CREB transcription factor activity 77604 77604 'Rbm12b2' mRNA 665.29 697.23 576.1 5.03 6.05 4.54 4.26 3.87 3.76 5.206666667 3.963333333 554.26 501.44 494.61 646.2066667 516.77 0.003732542 -0.332789621 GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding GO:0043484///regulation of RNA splicing 77605 77605 'H2az2' mRNA 2433 2395 2361 86.89 84.39 89.51 78.11 85.53 80.14 86.93 81.26 2509 2682 2494 2396.333333 2561.666667 0.313137095 0.084803225 04217///Necroptosis+++04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006342///chromatin silencing+++GO:0031507///heterochromatin assembly 77609 77609 'Ccdc151' mRNA 398 415 429 10.21 10.52 11.69 1.14 0.89 0.67 10.80666667 0.9 51 39 29 414 39.66666667 9.13E-59 -3.399163396 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0007283///spermatogenesis+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0030030///cell projection organization+++GO:0030317///flagellated sperm motility+++GO:0035264///multicellular organism growth+++GO:0036158///outer dynein arm assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0061371///determination of heart left/right asymmetry+++GO:0070286///axonemal dynein complex assembly+++GO:0090660///cerebrospinal fluid circulation+++GO:1902017///regulation of cilium assembly 77613 77613 'Prss36' mRNA 1358 1376 1284 30.94 29.96 29.94 20.9 21.52 21.01 30.28 21.14333333 1054 1098 1044 1339.333333 1065.333333 4.60E-05 -0.340872171 GO:0005576///extracellular region+++GO:0005737///cytoplasm GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis 77619 77619 'Prelid2' mRNA 64 60 69 6.24 5.8 7.14 4.94 5.52 6.53 6.393333333 5.663333333 58 63 74 64.33333333 65 0.998591786 0.001274439 GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space GO:1990050///phosphatidic acid transporter activity GO:0015914///phospholipid transport+++GO:0120009///intermembrane lipid transfer 77622 77622 'Apex2' mRNA 761.56 715.83 618.09 6.2 5.95 7.08 6.39 6.56 6.49 6.41 6.48 615.45 498.21 526.64 698.4933333 546.7666667 0.002203584 -0.363982617 03410///Base excision repair GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004527///exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0008270///zinc ion binding+++GO:0008311///double-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis 77626 77626 'Smpd4' mRNA 695 784 796 9.06 9.95 11.37 7.99 7.87 8.78 10.12666667 8.213333333 684 666 717 758.3333333 689 0.226080141 -0.152141979 00600///Sphingolipid metabolism GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005640///nuclear outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0004767///sphingomyelin phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0050290///sphingomyelin phosphodiesterase D activity GO:0001701///in utero embryonic development+++GO:0006685///sphingomyelin catabolic process+++GO:0007029///endoplasmic reticulum organization+++GO:0046475///glycerophospholipid catabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor 77627 77627 'Efcab6' mRNA 642 655 643 8.86 8.35 8.69 0.59 0.62 0.74 8.633333333 0.65 48 42 55 646.6666667 48.33333333 1.48E-103 -3.754597372 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 77629 77629 'Sphkap' mRNA 501 435 382 3.82 3.28 3.09 2.17 2.09 1.63 3.396666667 1.963333333 326 309 238 439.3333333 291 1.31E-04 -0.603662752 GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030018///Z disc GO:0051018///protein kinase A binding 77630 77630 'Prdm8' mRNA 0 0 1 0 0 0.01 0 0 0 0.003333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0042054///histone methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific) "GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0014003///oligodendrocyte development+++GO:0016571///histone methylation+++GO:0021540///corpus callosum morphogenesis+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0021957///corticospinal tract morphogenesis+++GO:0022008///neurogenesis+++GO:0032259///methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051567///histone H3-K9 methylation" 77632 77632 'Pramel13' mRNA 3 0 0 0.07 0 0 0 0 0 0.023333333 0 0 0 0 1 0 0.653555534 -2.427804616 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031462///Cul2-RING ubiquitin ligase complex "GO:0042974///retinoic acid receptor binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination" "GO:0008150///biological_process+++GO:0008284///positive regulation of cell proliferation+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0045596///negative regulation of cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated" 77634 77634 'Snapc3' mRNA 4314.03 4420.26 3710.4 29.75 30.25 28.87 19.19 21.53 21.26 29.62333333 20.66 3014.47 2636.24 3049.7 4148.23 2900.136667 3.40E-14 -0.526017917 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0019185///snRNA-activating protein complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001006///RNA polymerase III type 3 promoter sequence-specific DNA binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003681///bent DNA binding GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III 77644 77644 'C330007P06Rik' mRNA 1101.53 1290.57 1268.97 17.75 20.55 21.75 20.69 20.01 22.13 20.01666667 20.94333333 1471.86 1387.55 1522.47 1220.356667 1460.626667 0.013305122 0.245769479 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0044297///cell body GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0090158///endoplasmic reticulum membrane organization 77647 77647 'Trat1' mRNA 56.69 38.14 45.23 0.65 0.43 0.55 0.27 0.26 0.33 0.543333333 0.286666667 27.27 25.88 32.03 46.68666667 28.39333333 0.094790882 -0.739256943 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034451///centriolar satellite+++GO:0042101///T cell receptor complex+++GO:0072686///mitotic spindle GO:0003674///molecular_function GO:0001920///negative regulation of receptor recycling+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0051051///negative regulation of transport 77652 77652 'Zfp955a' mRNA 546.05 517.44 527.9 7.88 7.57 8.41 5.41 5.2 4.81 7.953333333 5.14 414.03 400.66 359.55 530.4633333 391.4133333 3.66E-04 -0.451655042 "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 77669 77669 'Arhgef38' mRNA 325 313 237 4.51 4.03 3.21 2.23 2.42 2.38 3.916666667 2.343333333 211 199 196 291.6666667 202 0.001777479 -0.536795257 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0005085///guanyl-nucleotide exchange factor activity GO:0050790///regulation of catalytic activity 77683 77683 'Ehmt1' mRNA 1117 1174 1163 11.84 12.23 13.06 9.73 9.08 8.82 12.37666667 9.21 1061 959 927 1151.333333 982.3333333 0.011600768 -0.242660339 00310///Lysine degradation+++04211///Longevity regulating pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0016604///nuclear body GO:0001222///transcription corepressor binding+++GO:0001226///RNA polymerase II transcription corepressor binding+++GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0046976///histone methyltransferase activity (H3-K27 specific)+++GO:0070742///C2H2 zinc finger domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006306///DNA methylation+++GO:0006325///chromatin organization+++GO:0016571///histone methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0032259///methylation+++GO:0034968///histone lysine methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045995///regulation of embryonic development+++GO:0051567///histone H3-K9 methylation+++GO:0060992///response to fungicide+++GO:0070734///histone H3-K27 methylation+++GO:0120162///positive regulation of cold-induced thermogenesis" 77697 77697 'Mmab' mRNA 712 889 775 13.1 16.1 15.12 7.63 7.78 8.02 14.77333333 7.81 477 475 484 792 478.6666667 1.24E-10 -0.737485929 00860///Porphyrin metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008817///cob(I)yrinic acid a,c-diamide adenosyltransferase activity+++GO:0016740///transferase activity+++GO:0031419///cobalamin binding" GO:0009235///cobalamin metabolic process 77701 77701 'Lcn12' mRNA 8 4 5 0.29 0.25 0.3 0.17 0.09 0.22 0.28 0.16 3 1 6 5.666666667 3.333333333 0.602813454 -0.778203139 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0001972///retinoic acid binding+++GO:0036094///small molecule binding GO:0008150///biological_process 77705 77705 'Cstdc2' mRNA 0 1 1 0 0.02 0.12 0 0 0 0.046666667 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004869///cysteine-type endopeptidase inhibitor activity GO:0010951///negative regulation of endopeptidase activity+++GO:0019730///antimicrobial humoral response 77706 77706 'Abcb5' mRNA 0 1 0 0 0.02 0 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 02010///ABC transporters GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances" GO:0001654///eye development+++GO:0030154///cell differentiation+++GO:0042391///regulation of membrane potential+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport 77717 77717 'Smim41' mRNA 2 6 1 0.14 0.28 0.03 0.75 0.72 0.81 0.15 0.76 19 25 21 3 21.66666667 7.58E-04 2.85729988 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77721 77721 'Mrps5' mRNA 524 524 515 21.74 21.45 22.67 19.69 22.26 24.24 21.95333333 22.06333333 545 601 649 521 598.3333333 0.156697337 0.188795115 03010///Ribosome GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0006412///translation 77727 77727 '6030468B19Rik' mRNA 0 1 1 0 0.07 0.06 0 0 0.16 0.043333333 0.053333333 0 0 3 0.666666667 1 0.879003105 0.567933165 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005125///cytokine activity GO:0002250///adaptive immune response+++GO:0002313///mature B cell differentiation involved in immune response+++GO:0002376///immune system process+++GO:0007166///cell surface receptor signaling pathway+++GO:0050776///regulation of immune response+++GO:2000558///positive regulation of immunoglobulin production in mucosal tissue 77733 77733 'Rnf170' mRNA 647.91 641.8 569.71 8.86 8.62 8.27 7.18 6.89 7.22 8.583333333 7.096666667 606 563.27 586.69 619.8066667 585.32 0.478766046 -0.091805585 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination 77739 77739 'Adamtsl1' mRNA 2061 1864 1899 12.45 11.09 12.17 2.42 2.11 2.27 11.90333333 2.266666667 459 396 424 1941.333333 426.3333333 1.63E-128 -2.200129819 GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0004222///metalloendopeptidase activity GO:0030198///extracellular matrix organization 77744 77744 'Bora' mRNA 116 118 111 2.33 2.35 2.36 2.22 2.25 2.54 2.346666667 2.336666667 127 125 141 115 131 0.514659159 0.176953913 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0072687///meiotic spindle GO:0019901///protein kinase binding GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division+++GO:0032147///activation of protein kinase activity+++GO:0032880///regulation of protein localization+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization 77763 77763 'Gm9736' mRNA 0 0 1 0 0 0.06 0 0 0 0.02 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005882///intermediate filament+++GO:0045095///keratin filament GO:0003674///molecular_function GO:0008150///biological_process 77766 77766 'Elp4' mRNA 312.76 379.32 358.81 2.45 2.92 2.98 2.26 1.92 2.28 2.783333333 2.153333333 332.78 275.88 324.4 350.2966667 311.02 0.285386881 -0.186063369 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0008023///transcription elongation factor complex+++GO:0033588///Elongator holoenzyme complex GO:0000993///RNA polymerase II complex binding+++GO:0008607///phosphorylase kinase regulator activity GO:0002098///tRNA wobble uridine modification+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008033///tRNA processing+++GO:0050790///regulation of catalytic activity 77767 77767 'Ermn' mRNA 1 0 0 0.09 0 0 0 0 0 0.03 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0030175///filopodium+++GO:0033269///internode region of axon+++GO:0033270///paranode region of axon+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0001763///morphogenesis of a branching structure+++GO:0007015///actin filament organization+++GO:0008360///regulation of cell shape+++GO:0031344///regulation of cell projection organization 77771 77771 'Csrnp3' mRNA 22 30 34 0.11 0.14 0.18 0.07 0.04 0.09 0.143333333 0.066666667 17 9 20 28.66666667 15.33333333 0.123480067 -0.923262727 GO:0005634///nucleus "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II 77772 77772 'Dcst1' mRNA 23 14 17 0.55 0.33 0.43 0.25 0.17 0.34 0.436666667 0.253333333 12 8 16 18 12 0.435927946 -0.598409471 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0002376///immune system process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0045087///innate immune response+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway 77777 77777 'Ulbp1' mRNA 2 3 3 0.06 0.12 0.13 1.39 1.51 1.61 0.103333333 1.503333333 41 44 50 2.666666667 45 5.18E-09 4.065835456 04650///Natural killer cell mediated cytotoxicity GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0046658///anchored component of plasma membrane GO:0046703///natural killer cell lectin-like receptor binding GO:0002839///positive regulation of immune response to tumor cell+++GO:0006955///immune response+++GO:0030101///natural killer cell activation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032816///positive regulation of natural killer cell activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0043032///positive regulation of macrophage activation+++GO:0045429///positive regulation of nitric oxide biosynthetic process 77781 77781 'Epm2aip1' mRNA 1649 1638 1250 12 11.72 9.65 7.87 7.42 7.69 11.12333333 7.66 1245 1148 1179 1512.333333 1190.666667 2.05E-04 -0.351976764 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0098554///cytoplasmic side of endoplasmic reticulum membrane GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0032868///response to insulin+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:2000467///positive regulation of glycogen (starch) synthase activity 77782 77782 'Polq' mRNA 37 36 26 0.22 0.24 0.19 0.5 0.44 0.45 0.216666667 0.463333333 95 72 75 33 80.66666667 1.74E-04 1.280424528 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005524///ATP binding+++GO:0008409///5'-3' exonuclease activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0042802///identical protein binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0032508///DNA duplex unwinding+++GO:0051260///protein homooligomerization+++GO:0071897///DNA biosynthetic process+++GO:0097681///double-strand break repair via alternative nonhomologous end joining+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 77794 77794 'Adamtsl2' mRNA 41 37 42 0.62 0.55 0.67 1.32 1.11 1.35 0.613333333 1.26 101 83 100 40 94.66666667 6.76E-05 1.228032288 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0050436///microfibril binding GO:0030198///extracellular matrix organization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060481///lobar bronchus epithelium development 77798 77798 'A930009A15Rik' mRNA 279.93 242 245.93 2.25 1.93 2.1 0.13 0.41 0.56 2.093333333 0.366666667 27.34 40.06 50 255.9533333 39.13333333 6.01E-29 -2.720163247 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77799 77799 'Sla2' mRNA 2 9 1 0.08 0.35 0.04 0.22 0.22 0.41 0.156666667 0.283333333 6 6 11 4 7.666666667 0.472546526 0.953804612 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle "GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0035591///signaling adaptor activity+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity+++GO:0047485///protein N-terminus binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0009966///regulation of signal transduction+++GO:0042110///T cell activation+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0050849///negative regulation of calcium-mediated signaling+++GO:0050860///negative regulation of T cell receptor signaling pathway 77803 77803 'Shisal2b' mRNA 0 2 2 0 0.09 0.1 0 0 0.17 0.063333333 0.056666667 0 0 4 1.333333333 1.333333333 0.998591786 -0.01817845 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77805 77805 'Esco1' mRNA 717 729.98 735 9 9.07 9.63 7.7 7.8 7.86 9.233333333 7.786666667 702 693.67 691.01 727.3266667 695.56 0.546297109 -0.076988713 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005694///chromosome "GO:0008080///N-acetyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016407///acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity" GO:0006275///regulation of DNA replication+++GO:0007049///cell cycle+++GO:0007062///sister chromatid cohesion+++GO:0018394///peptidyl-lysine acetylation+++GO:0034421///post-translational protein acetylation 77809 77809 'Lrrc42' mRNA 453.09 471.05 403.01 14.96 15.32 14.13 14.07 13.27 13.82 14.80333333 13.72 490.1 451.05 464.16 442.3833333 468.4366667 0.643068797 0.07236306 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77827 77827 'Krba1' mRNA 859 898 845 6.56 6.79 6.83 3.52 3.29 3.32 6.726666667 3.376666667 539 491 489 867.3333333 506.3333333 3.98E-15 -0.788694863 GO:0005575///cellular_component GO:0003674///molecular_function "GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process" 77832 77832 'Tchp' mRNA 478.81 483.8 476.01 9.03 8.93 9.43 6.03 5.12 4.92 9.13 5.356666667 370.98 302.02 293.86 479.54 322.2866667 1.71E-05 -0.588482216 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030057///desmosome+++GO:0045095///keratin filament+++GO:0045179///apical cortex+++GO:0097539///ciliary transition fiber GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0030030///cell projection organization+++GO:0030308///negative regulation of cell growth+++GO:1902018///negative regulation of cilium assembly" 77836 77836 'Mlana' mRNA 331 340 327 36.79 42.05 38 66.68 69.84 67.02 38.94666667 67.84666667 625 688 641 332.6666667 651.3333333 9.75E-16 0.958566096 GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042470///melanosome 77853 77853 'Msl2' mRNA 232 250 200 2.47 2.65 2.28 1.84 1.79 2.15 2.466666667 1.926666667 195 187 220 227.3333333 200.6666667 0.357200053 -0.188283731 GO:0072487///MSL complex GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0043984///histone H4-K16 acetylation 77862 77862 'Thyn1' mRNA 361.65 349.79 407.78 26.4 24.85 31.02 36.46 38.42 38.45 27.42333333 37.77666667 556.57 569.44 570.36 373.0733333 565.4566667 9.27E-06 0.586628449 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 77864 77864 'Ypel2' mRNA 1128 1144 941 11.43 11.26 9.89 7.02 5.89 6.98 10.86 6.63 816 663 773 1071 750.6666667 2.63E-07 -0.522440216 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003674///molecular_function+++GO:0046872///metal ion binding GO:0008150///biological_process 77877 77877 '6030458C11Rik' mRNA 810.98 856.13 855.17 14.14 14.41 15.72 11.04 10.21 10.76 14.75666667 10.67 701.33 648.77 657 840.76 669.0333333 9.42E-04 -0.343144806 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 77883 77883 '6030498E09Rik' mRNA 7 6 6 0.36 0.31 0.33 0 0.09 0.09 0.333333333 0.06 0 2 2 6.333333333 1.333333333 0.132214435 -2.250441853 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 77889 77889 'Lbh' mRNA 863 808 567 15.43 14.21 10.75 9.43 9.64 10.09 13.46333333 9.72 607 606 629 746 614 0.038768505 -0.284945444 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex "GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030879///mammary gland development+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060644///mammary gland epithelial cell differentiation+++GO:1904674///positive regulation of somatic stem cell population maintenance+++GO:1904677///positive regulation of somatic stem cell division+++GO:2000103///positive regulation of mammary stem cell proliferation+++GO:2000737///negative regulation of stem cell differentiation" 77891 77891 'Ube2s' mRNA 170 174 133 11.03 11.17 9.16 11.89 9.93 9.96 10.45333333 10.59333333 210 171 170 159 183.6666667 0.392326501 0.199041505 04120///Ubiquitin mediated proteolysis GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0010997///anaphase-promoting complex binding+++GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0010458///exit from mitosis+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0035519///protein K29-linked ubiquitination+++GO:0044314///protein K27-linked ubiquitination+++GO:0051301///cell division+++GO:0070534///protein K63-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination+++GO:1904668///positive regulation of ubiquitin protein ligase activity 77914 77914 'Krtap17-1' mRNA 0 0 1 0 0 0.1 0 0 0 0.033333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0003674///molecular_function GO:0008150///biological_process 77929 77929 'Yipf6' mRNA 1135 1301 1269 12.43 13.88 14.73 11.88 11.4 11.41 13.68 11.56333333 1245 1167 1150 1235 1187.333333 0.542815183 -0.070422485 GO:0000138///Golgi trans cisterna+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005797///Golgi medial cisterna+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle GO:0042802///identical protein binding GO:0060576///intestinal epithelial cell development 77938 77938 'Fam53b' mRNA 729 833 803 7.56 8.47 8.82 7.54 7.16 8.12 8.283333333 7.606666667 837 777 878 788.3333333 830.6666667 0.649773958 0.062441783 GO:0005634///nucleus GO:0003674///molecular_function GO:0006606///protein import into nucleus+++GO:0016055///Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway 77945 77945 'Rpgrip1' mRNA 140.89 129.13 180.43 1.8 1.61 2.47 0.76 0.69 0.96 1.96 0.803333333 66.93 56.42 78.49 150.15 67.28 9.33E-06 -1.186985418 GO:0005929///cilium+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0035253///ciliary rootlet+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection+++GO:0097730///non-motile cilium GO:0005515///protein binding GO:0007601///visual perception+++GO:0042462///eye photoreceptor cell development+++GO:0046548///retinal rod cell development+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:0061351///neural precursor cell proliferation+++GO:1905515///non-motile cilium assembly 77951 77951 'Cyp20a1' mRNA 656.39 550.34 588.24 16.75 13.82 15.95 18.54 18.94 19.02 15.50666667 18.83333333 838.35 838.31 835.54 598.3233333 837.4 1.50E-05 0.472842429 GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding" 77963 77963 'Hook1' mRNA 849 937 760 12.06 13.62 11.36 4.32 4.55 4.32 12.34666667 4.396666667 367 327 328 848.6666667 340.6666667 4.68E-33 -1.326295076 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0030897///HOPS complex+++GO:0070695///FHF complex GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0051959///dynein light intermediate chain binding GO:0007030///Golgi organization+++GO:0007032///endosome organization+++GO:0007040///lysosome organization+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0030154///cell differentiation+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0045022///early endosome to late endosome transport+++GO:1905198///manchette assembly+++GO:1905719///protein localization to perinuclear region of cytoplasm 77974 77974 'Rdh12' mRNA 1069 1149 1017 37.08 39.27 37.39 5.2 6.03 4.71 37.91333333 5.313333333 172 195 151 1078.333333 172.6666667 7.38E-107 -2.652585192 00830///Retinol metabolism+++01240///Biosynthesis of cofactors GO:0001917///photoreceptor inner segment GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0102354///11-cis-retinol dehydrogenase activity GO:0007601///visual perception+++GO:0042572///retinol metabolic process+++GO:0050896///response to stimulus+++GO:0110095///cellular detoxification of aldehyde 77975 77975 'Tmem50b' mRNA 2124 2182 2121 53.78 54.41 56.97 47.22 46.25 50.86 55.05333333 48.11 2144 2051 2238 2142.333333 2144.333333 0.909001411 -0.010886572 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway 77976 77976 'Nuak1' mRNA 370 361 311 1.73 1.65 1.55 0.94 0.74 0.82 1.643333333 0.833333333 225 176 186 347.3333333 195.6666667 1.23E-07 -0.838857637 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton GO:0000166///nucleotide binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007155///cell adhesion+++GO:0016310///phosphorylation+++GO:0030155///regulation of cell adhesion+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0035556///intracellular signal transduction+++GO:0042149///cellular response to glucose starvation+++GO:2000772///regulation of cellular senescence 77980 77980 'Sbf1' mRNA 2377 2472 1950 19.52 19.75 17.01 16.42 14.97 15.32 18.76 15.57 2297 2036 2064 2266.333333 2132.333333 0.29100595 -0.096392697 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0048471///perinuclear region of cytoplasm GO:0001691///pseudophosphatase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019208///phosphatase regulator activity GO:0001558///regulation of cell growth+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0043086///negative regulation of catalytic activity+++GO:0043087///regulation of GTPase activity 77987 77987 'Ascc3' mRNA 597 640 632 4.2 4.44 4.72 5.45 5.11 5.89 4.453333333 5.483333333 891 815 933 623 879.6666667 4.19E-06 0.484654455 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0099053///activating signal cointegrator 1 complex GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0043138///3'-5' DNA helicase activity GO:0006281///DNA repair+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0032508///DNA duplex unwinding+++GO:0072344///rescue of stalled ribosome+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process 77996 77996 'Cutal' mRNA 745 785 703 17.78 18.44 17.82 15.6 16.2 16.55 18.01333333 16.11666667 752 763 773 744.3333333 762.6666667 0.863090843 0.024916421 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005507///copper ion binding GO:0008150///biological_process+++GO:0010038///response to metal ion 77998 77998 'Grifin' mRNA 0 0 1 0 0 0.16 0 0 0 0.053333333 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0030246///carbohydrate binding GO:0008150///biological_process 78004 78004 'Prr15' mRNA 1914 1739 1815 75.87 67.97 76.32 19.53 18.44 19.62 73.38666667 19.19666667 566 523 550 1822.666667 546.3333333 6.88E-87 -1.751461039 GO:0005575///cellular_component GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0008150///biological_process 78016 78016 'Ccdc150' mRNA 5 15 9 0.09 0.25 0.19 0.03 0 0.03 0.176666667 0.02 2 0 2 9.666666667 1.333333333 0.029321314 -2.870893282 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78038 78038 'Mccc2' mRNA 736 758 883 19.6 19.89 24.95 15.66 16.16 15.77 21.48 15.86333333 676 681 659 792.3333333 672 0.046402484 -0.254031346 "00280///Valine, leucine and isoleucine degradation" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:1905202///methylcrotonoyl-CoA carboxylase complex GO:0000166///nucleotide binding+++GO:0004485///methylcrotonoyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity GO:0006552///leucine catabolic process+++GO:0015936///coenzyme A metabolic process 78052 78052 'Tmem190' mRNA 2 3 1 0.24 0.25 0.14 0.12 0 0.24 0.21 0.12 1 0 2 2 1 0.711044481 -0.998978768 GO:0002079///inner acrosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0043621///protein self-association GO:0002244///hematopoietic progenitor cell differentiation 78070 78070 'Cpt1c' mRNA 1352 1412 1372 27.47 28.39 29.58 19.8 19.9 18.29 28.48 19.33 1130 1097 999 1378.666667 1075.333333 2.33E-05 -0.371084527 00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04152///AMPK signaling pathway+++04714///Thermogenesis+++04920///Adipocytokine signaling pathway+++04922///Glucagon signaling pathway+++04936///Alcoholic liver disease GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0032281///AMPA glutamate receptor complex+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse "GO:0004095///carnitine O-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0009437///carnitine metabolic process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels 78076 78076 'Lcn8' mRNA 14 13 22 1.58 1.46 2.63 1.97 1.93 2.35 1.89 2.083333333 20 19 23 16.33333333 20.66666667 0.673646829 0.316988872 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function+++GO:0005501///retinoid binding+++GO:0036094///small molecule binding GO:0009725///response to hormone+++GO:0042573///retinoic acid metabolic process 78088 78088 'Sowahb' mRNA 383 373 94 5.31 5.08 1.38 1.08 1.87 2.19 3.923333333 1.713333333 90 152 176 283.3333333 139.3333333 0.169314143 -1.004053401 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78100 78100 'Msantd4' mRNA 792 802 769 15.44 15.39 15.9 18.82 16.71 18.6 15.57666667 18.04333333 1111 963 1063 787.6666667 1045.666667 2.56E-05 0.39615673 GO:0005634///nucleus GO:0003674///molecular_function GO:0008150///biological_process 78134 78134 'Lpar4' mRNA 41 50 32 0.52 0.62 0.43 0.52 0.53 0.73 0.523333333 0.593333333 47 47 64 41 52.66666667 0.415593868 0.35687251 04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0043231///intracellular membrane-bounded organelle GO:0004930///G protein-coupled receptor activity+++GO:0008289///lipid binding+++GO:0035727///lysophosphatidic acid binding+++GO:0070915///lysophosphatidic acid receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 78174 78174 'Cox7b2' mRNA 0 0 2 0 0 0.32 0.26 0 0 0.106666667 0.086666667 2 0 0 0.666666667 0.666666667 0.988201161 -0.104372075 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005746///mitochondrial respiratory chain+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045277///respiratory chain complex IV GO:0003674///molecular_function+++GO:0004129///cytochrome-c oxidase activity GO:0006119///oxidative phosphorylation+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport 78177 78177 'Ninl' mRNA 180 190 167 1.91 1.99 1.92 1.33 1.37 1.15 1.94 1.283333333 140 141 124 179 135 0.046268257 -0.417179549 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0045171///intercellular bridge GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0034454///microtubule anchoring at centrosome 78232 78232 'Trappc6b' mRNA 1364 1342 882 63.93 62.21 44.15 39.71 50.4 55 56.76333333 48.37 964 1199 1294 1196 1152.333333 0.777867136 -0.053845367 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0030008///TRAPP complex GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007399///nervous system development+++GO:0043087///regulation of GTPase activity+++GO:0048193///Golgi vesicle transport 78244 78244 'Dnajc21' mRNA 106.53 103.11 94.87 2.23 2.41 2.33 3.27 2.75 3.07 2.323333333 3.03 144.83 126.45 130.01 101.5033333 133.7633333 0.112100694 0.389372584 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0008150///biological_process 78245 78245 'Acbd7' mRNA 2605 2525 2517 395.84 382.71 406.05 46.71 50.04 42.98 394.8666667 46.57666667 350 364 310 2549 341.3333333 4.47E-233 -2.912944314 GO:0005575///cellular_component GO:0000062///fatty-acyl-CoA binding+++GO:0003674///molecular_function+++GO:0008289///lipid binding GO:0008150///biological_process 78246 78246 'Phf23' mRNA 715 738 542 21.74 22.5 17.69 31.31 34.96 31.53 20.64333333 32.6 1142 1261 1122 665 1175 4.70E-14 0.81599222 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0046872///metal ion binding GO:0006914///autophagy+++GO:0031398///positive regulation of protein ubiquitination+++GO:1901097///negative regulation of autophagosome maturation+++GO:1902902///negative regulation of autophagosome assembly 78248 78248 'Armcx1' mRNA 1042 1100 1105 24.41 24.88 26.94 12.61 14.16 11.59 25.41 12.78666667 625 686 560 1082.333333 623.6666667 4.60E-14 -0.807873254 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0061484///hematopoietic stem cell homeostasis 78249 78249 'Adgrf4' mRNA 1 1 4 0.02 0.02 0.06 0.15 0.18 0.27 0.033333333 0.2 10 11 16 2 12.33333333 0.018096303 2.595941467 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0003094///glomerular filtration+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0048821///erythrocyte development+++GO:0061626///pharyngeal arch artery morphogenesis 78250 78250 'Iqch' mRNA 7 14 8 0.11 0.2 0.13 0.12 0.1 0.08 0.146666667 0.1 9 8 6 9.666666667 7.666666667 0.758356975 -0.340894917 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78251 78251 'Zfp712' mRNA 157 143 156 2.14 1.91 2.25 0.71 0.86 1.01 2.1 0.86 60 71 83 152 71.33333333 7.68E-06 -1.10348377 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 78252 78252 'Nxpe2' mRNA 16 16 16.14 0.37 0.3 0.36 0.48 0.52 0.31 0.343333333 0.436666667 32 28 18.81 16.04666667 26.27 0.263262754 0.686246489 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 78255 78255 'Ralgps2' mRNA 572 559 577 4.69 4.45 4.9 2.72 2.81 2.94 4.68 2.823333333 355 344 350 569.3333333 349.6666667 3.53E-09 -0.716404254 GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003674///molecular_function+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0007264///small GTPase mediated signal transduction+++GO:0008150///biological_process+++GO:0032485///regulation of Ral protein signal transduction+++GO:0050790///regulation of catalytic activity 78257 78257 'Lrrc9' mRNA 385 453 399 5.6 5.69 5.77 0.64 0.74 0.72 5.686666667 0.7 46 62 50 412.3333333 52.66666667 1.96E-53 -2.978490138 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78266 78266 'Zfp687' mRNA 2382.3 2323.4 1630.65 21.33 20.81 14.11 7.95 9.06 8.54 18.75 8.516666667 1149.42 1167.21 1119.95 2112.116667 1145.526667 1.12E-17 -0.886896798 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046872///metal ion binding GO:0008150///biological_process 78267 78267 'Klhdc8b' mRNA 489 548 455 10.57 11.9 11.06 8.09 8.19 9.24 11.17666667 8.506666667 412 425 472 497.3333333 436.3333333 0.157558316 -0.197485522 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0110070///cellularization cleavage furrow GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0098813///nuclear chromosome segregation+++GO:0140014///mitotic nuclear division+++GO:1902410///mitotic cytokinetic process 78283 78283 'Map7d2' mRNA 332 328 304 9.47 8.43 8.16 3.86 4.48 4.26 8.686666667 4.2 143 159 143 321.3333333 148.3333333 5.93E-12 -1.125231984 GO:0015630///microtubule cytoskeleton GO:0000226///microtubule cytoskeleton organization 78284 78284 'Creb3l4' mRNA 418 481 469 16.87 19.33 20.9 8.72 8.49 8.17 19.03333333 8.46 251 237 236 456 241.3333333 3.72E-11 -0.93144055 "04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04151///PI3K-Akt signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04261///Adrenergic signaling in cardiomyocytes+++04668///TNF signaling pathway+++04714///Thermogenesis+++04725///Cholinergic synapse+++04728///Dopaminergic synapse+++04911///Insulin secretion+++04915///Estrogen signaling pathway+++04916///Melanogenesis+++04918///Thyroid hormone synthesis+++04922///Glucagon signaling pathway+++04925///Aldosterone synthesis and secretion+++04926///Relaxin signaling pathway+++04927///Cortisol synthesis and secretion+++04928///Parathyroid hormone synthesis, secretion and action+++04931///Insulin resistance+++04934///Cushing syndrome+++04935///Growth hormone synthesis, secretion and action+++04962///Vasopressin-regulated water reabsorption+++05016///Huntington disease+++05020///Prion disease+++05030///Cocaine addiction+++05031///Amphetamine addiction+++05034///Alcoholism+++05161///Hepatitis B+++05163///Human cytomegalovirus infection+++05165///Human papillomavirus infection+++05166///Human T-cell leukemia virus 1 infection+++05203///Viral carcinogenesis+++05207///Chemical carcinogenesis - receptor activation+++05215///Prostate cancer" GO:0000139///Golgi membrane+++GO:0002079///inner acrosomal membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0045944///positive regulation of transcription by RNA polymerase II" 78286 78286 'Nav2' mRNA 1505.93 1484.96 1580.85 7.07 6.83 7.9 3.85 3.72 4.26 7.266666667 3.943333333 1041.86 979.99 1095.77 1523.913333 1039.206667 3.65E-10 -0.56684382 GO:0005614///interstitial matrix+++GO:0005654///nucleoplasm+++GO:0031012///extracellular matrix GO:0008201///heparin binding+++GO:0043138///3'-5' DNA helicase activity GO:0003025///regulation of systemic arterial blood pressure by baroreceptor feedback+++GO:0007399///nervous system development+++GO:0007605///sensory perception of sound+++GO:0007608///sensory perception of smell+++GO:0007626///locomotory behavior+++GO:0021554///optic nerve development+++GO:0021563///glossopharyngeal nerve development+++GO:0021564///vagus nerve development+++GO:0021695///cerebellar cortex development+++GO:0022008///neurogenesis 78287 78287 'Rbsn' mRNA 822 821 901 8.3 8.18 9.65 6.66 7.23 7.35 8.71 7.08 760 805 805 848 790 0.358402334 -0.116216823 04144///Endocytosis GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0031267///small GTPase binding+++GO:0046872///metal ion binding GO:0015031///protein transport+++GO:0034498///early endosome to Golgi transport+++GO:0090160///Golgi to lysosome transport+++GO:1903358///regulation of Golgi organization 78294 78294 'Rps27a' mRNA 4123 3884 3860 392.85 366.23 390.51 497.59 515.74 498.99 383.1966667 504.1066667 5979 6042 5787 3955.666667 5936 6.64E-22 0.573796382 03010///Ribosome+++04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++05012///Parkinson disease+++05022///Pathways of neurodegeneration - multiple diseases+++05131///Shigellosis+++05167///Kaposi sarcoma-associated herpesvirus infection+++05171///Coronavirus disease - COVID-19 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0022626///cytosolic ribosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath GO:0002020///protease binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0031386///protein tag+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding GO:0006412///translation+++GO:0007141///male meiosis I+++GO:0007144///female meiosis I+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0016567///protein ubiquitination+++GO:0019941///modification-dependent protein catabolic process+++GO:0021888///hypothalamus gonadotrophin-releasing hormone neuron development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0047497///mitochondrion transport along microtubule+++GO:0048812///neuron projection morphogenesis+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0060612///adipose tissue development+++GO:0060613///fat pad development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072520///seminiferous tubule development+++GO:0097009///energy homeostasis+++GO:1901214///regulation of neuron death+++GO:1902255///positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:1902527///positive regulation of protein monoubiquitination 78303 78303 'H2bu2' mRNA 916 811 641 177.49 157.59 131.91 49.69 52.33 51.71 155.6633333 51.24333333 291 297 291.01 789.3333333 293.0033333 9.79E-29 -1.435773125 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly 78304 78304 'Naa38' mRNA 683.55 638.28 739.88 109.37 102.05 125.69 90.94 113.54 101.31 112.37 101.93 646.73 783.59 693.3 687.2366667 707.8733333 0.863090843 0.029124527 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0031417///NatC complex GO:0003674///molecular_function GO:0043066///negative regulation of apoptotic process 78306 78306 'Tsga10ip' mRNA 0 3 1 0 0.1 0.04 0.09 0.03 0.06 0.046666667 0.06 3 1 2 1.333333333 2 0.834051226 0.577762364 GO:0005929///cilium+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body GO:0003674///molecular_function GO:0044782///cilium organization 78308 78308 'Gpr108' mRNA 2727 2868 2688 71.98 74.64 75.2 61.45 64.69 63.06 73.94 63.06666667 2680 2754 2656 2761 2696.666667 0.594133513 -0.045162064 GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033106///cis-Golgi network membrane GO:0003674///molecular_function GO:0006810///transport+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0050776///regulation of immune response 78309 78309 'Cul9' mRNA 808 834 765 5.37 5.48 5.42 3.03 2.54 2.93 5.423333333 2.833333333 524 428 490 802.3333333 480.6666667 2.81E-12 -0.751365548 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding GO:0000226///microtubule cytoskeleton organization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination 78317 78317 'Ccdc88b' mRNA 43 46 31 0.54 0.51 0.41 1.9 2.39 2.11 0.486666667 2.133333333 176 224 208 40 202.6666667 1.65E-20 2.336555885 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0016020///membrane GO:0008017///microtubule binding+++GO:0051959///dynein light intermediate chain binding GO:0001819///positive regulation of cytokine production+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0031122///cytoplasmic microtubule organization+++GO:0042102///positive regulation of T cell proliferation+++GO:0042832///defense response to protozoan+++GO:0050870///positive regulation of T cell activation 78321 78321 'Ankrd23' mRNA 501 520 507 12.09 12.33 13.06 9.82 9.97 9.29 12.49333333 9.693333333 467 462 428 509.3333333 452.3333333 0.167383081 -0.183504368 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0014704///intercalated disc+++GO:0015629///actin cytoskeleton+++GO:0030016///myofibril+++GO:0031674///I band GO:0031432///titin binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006631///fatty acid metabolic process+++GO:0035994///response to muscle stretch+++GO:0060297///regulation of sarcomere organization 78323 78323 'Fam219b' mRNA 874.11 899.08 859.96 15.24 15.37 15.94 10.98 11.39 13.76 15.51666667 12.04333333 719.35 724.98 875.71 877.7166667 773.3466667 0.101269742 -0.194402807 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78330 78330 'Ndufv3' mRNA 2129 2061 2139 215.94 207.11 248.01 173.39 208.93 202.97 223.6866667 195.0966667 1733 1957 1822 2109.666667 1837.333333 0.017376873 -0.211442562 00190///Oxidative phosphorylation+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0070469///respiratory chain GO:0042775///mitochondrial ATP synthesis coupled electron transport 78334 78334 'Cdk19' mRNA 2370 2572 2041 21.94 23.32 20.11 14.09 12.91 13.1 21.79 13.36666667 1719 1562 1559 2327.666667 1613.333333 3.08E-12 -0.53751972 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016592///mediator complex+++GO:0048471///perinuclear region of cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0050729///positive regulation of inflammatory response+++GO:0051726///regulation of cell cycle+++GO:0071222///cellular response to lipopolysaccharide 78339 78339 'Ttyh3' mRNA 387 411 196 4.42 4.6 2.36 5.23 5.4 5.29 3.793333333 5.306666667 525 528 519 331.3333333 524 6.06E-04 0.663778774 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034707///chloride channel complex GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0072320///volume-sensitive chloride channel activity GO:0006811///ion transport+++GO:0006821///chloride transport 78354 78354 'Lypd8l' mRNA 0 0 1 0 0 0.08 0.07 0 0 0.026666667 0.023333333 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 GO:0005575///cellular_component GO:0003674///molecular_function GO:0009617///response to bacterium 78369 78369 'Icam4' mRNA 60 86 70 4.13 5.57 4.96 2.83 1.84 1.54 4.886666667 2.07 51 30 27 72 36 0.007413116 -1.015281158 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005178///integrin binding GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion 78372 78372 'Snrnp25' mRNA 500 529 460 40.37 42.31 39.41 35.75 38.51 38.84 40.69666667 37.7 507 532 532 496.3333333 523.6666667 0.653604251 0.067987398 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005829///cytosol+++GO:0045171///intercellular bridge GO:0003674///molecular_function "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008150///biological_process+++GO:0008380///RNA splicing" 78373 78373 'Nudt17' mRNA 124.37 104.26 123 6.05 4.86 6.19 8.57 6.74 6.25 5.7 7.186666667 207 159 148 117.21 171.3333333 0.023030468 0.533347858 GO:0005777///peroxisome+++GO:0005829///cytosol GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0046872///metal ion binding GO:0006734///NADH metabolic process+++GO:0006742///NADP catabolic process+++GO:0019677///NAD catabolic process 78376 78376 'Sapcd1' mRNA 62.81 31.7 46.82 3.13 1.36 2.16 1.62 1.91 2.19 2.216666667 1.906666667 41.64 39.71 47.97 47.11 43.10666667 0.791143807 -0.144248125 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78382 78382 'Lce6a' mRNA 414 365 359 42.83 38.08 41.77 6.02 5.43 5.02 40.89333333 5.49 72 58 60 379.3333333 63.33333333 3.02E-44 -2.594734493 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78388 78388 'Mvp' mRNA 1364 1360 1435 26.79 26.33 29.91 53.39 53.01 53.04 27.67666667 53.14666667 3126 3030 3007 1386.333333 3054.333333 6.32E-53 1.125750209 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding GO:0008283///cell proliferation+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0038127///ERBB signaling pathway+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0072376///protein activation cascade 78394 78394 'Ddx52' mRNA 673 773 766 11.63 13.15 14.05 11.39 11.72 12.09 12.94333333 11.73333333 758 762 779 737.3333333 766.3333333 0.775274785 0.04249737 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity GO:0030490///maturation of SSU-rRNA 78405 78405 'Ntf5' mRNA 32 41 16 0.93 1.17 0.49 0.82 0.71 1.04 0.863333333 0.856666667 34 28 40 29.66666667 34 0.750936661 0.198802334 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04722///Neurotrophin signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0008021///synaptic vesicle+++GO:0030424///axon+++GO:0030425///dendrite GO:0005102///signaling receptor binding+++GO:0005163///nerve growth factor receptor binding+++GO:0005166///neurotrophin p75 receptor binding+++GO:0008083///growth factor activity GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007402///ganglion mother cell fate determination+++GO:0007422///peripheral nervous system development+++GO:0007613///memory+++GO:0007616///long-term memory+++GO:0008052///sensory organ boundary specification+++GO:0008344///adult locomotory behavior+++GO:0008544///epidermis development+++GO:0021675///nerve development+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0038180///nerve growth factor signaling pathway+++GO:0042490///mechanoreceptor differentiation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060384///innervation+++GO:0060548///negative regulation of cell death+++GO:0061193///taste bud development 78408 78408 'Fam131a' mRNA 1229.25 1284.8 1095.64 28.8 29.48 27.22 19.75 16.24 21.42 28.5 19.13666667 949.35 770.63 996.67 1203.23 905.55 4.96E-05 -0.42074243 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78412 78412 'Cyren' mRNA 185.74 160.29 210.94 3.21 2.89 3.81 3.79 4.28 3.8 3.303333333 3.956666667 234.8 222.71 244.46 185.6566667 233.99 0.123409632 0.317720197 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035861///site of double-strand break GO:0003674///molecular_function+++GO:0005515///protein binding GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0033152///immunoglobulin V(D)J recombination+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining 78414 78414 '1700034E13Rik' mRNA 2 2 2 0.37 0.37 0.39 0.16 0 0 0.376666667 0.053333333 1 0 0 2 0.333333333 0.371313523 -2.493392462 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78416 78416 'Rnase6' mRNA 44 57 39 1.12 1.46 1.08 3.01 2.23 2.97 1.22 2.736666667 133 96 128 46.66666667 119 3.51E-06 1.341168202 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0019731///antibacterial humoral response+++GO:0042742///defense response to bacterium+++GO:0045087///innate immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051607///defense response to virus+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0090501///RNA phosphodiester bond hydrolysis 78428 78428 'Pym1' mRNA 200 202 159 10.04 10.18 8.52 11.23 11.53 10.56 9.58 11.10666667 253 251 229 187 244.3333333 0.039379157 0.377912507 03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0035145///exon-exon junction complex GO:0003723///RNA binding+++GO:0043022///ribosome binding "GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation+++GO:0045727///positive regulation of translation+++GO:1903259///exon-exon junction complex disassembly" 78444 78444 'Pgpep1l' mRNA 25.76 39.65 27.69 0.2 0.32 0.24 0.07 0.14 0.12 0.253333333 0.11 11.31 20.28 18.05 31.03333333 16.54666667 0.117818711 -0.896398591 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003674///molecular_function+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016920///pyroglutamyl-peptidase activity GO:0006508///proteolysis 78455 78455 'Helz' mRNA 1843 1840 1737 8.96 8.38 8.8 7.12 5.91 6.81 8.713333333 6.613333333 1614 1310 1479 1806.666667 1467.666667 2.00E-04 -0.312670031 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043186///P granule GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0035194///posttranscriptional gene silencing by RNA 78465 78465 'Ccdc190' mRNA 35 50 25 0.45 0.6 0.33 0.09 0.14 0.08 0.46 0.103333333 5 8 3 36.66666667 5.333333333 1.45E-05 -2.779672911 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78473 78473 'Skap1' mRNA 4 13 3 0.11 0.49 0.13 0.7 0.31 0.52 0.243333333 0.51 22 8 22 6.666666667 17.33333333 0.117604156 1.378963632 04015///Rap1 signaling pathway GO:0001772///immunological synapse+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0042101///T cell receptor complex+++GO:0044853///plasma membrane raft GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0042169///SH2 domain binding+++GO:0044877///protein-containing complex binding "GO:0001954///positive regulation of cell-matrix adhesion+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0002821///positive regulation of adaptive immune response+++GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0045785///positive regulation of cell adhesion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050852///T cell receptor signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:1903039///positive regulation of leukocyte cell-cell adhesion" 78506 78506 'Micu3' mRNA 1129.74 1003 1009 16.36 13.95 15.81 7.98 5.94 8.37 15.37333333 7.43 629.98 486 630.16 1047.246667 582.0466667 2.11E-14 -0.86135082 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990246///uniplex complex GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051560///mitochondrial calcium ion homeostasis 78514 78514 'Arhgap10' mRNA 379 357 336 6.69 6.2 6.37 5.46 6.46 6.87 6.42 6.263333333 352 405 422 357.3333333 393 0.450361362 0.128054214 05100///Bacterial invasion of epithelial cells GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0005096///GTPase activator activity+++GO:0005515///protein binding GO:0007010///cytoskeleton organization+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity 78521 78521 'B230219D22Rik' mRNA 3238 3464 1265 37.3 39.24 15.46 11.17 12.04 13.77 30.66666667 12.32666667 1116 1175 1333 2655.666667 1208 0.011514146 -1.126372261 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78523 78523 'Mrpl9' mRNA 1024.36 1007.15 957 37.49 36.35 37.16 41.56 39.26 38.76 37 39.86 1303.47 1202.69 1177.2 996.17 1227.786667 8.53E-04 0.289428609 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003674///molecular_function+++GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0008150///biological_process 78541 78541 'Asb8' mRNA 2516 2590 2570 64.73 65.95 70.53 31.66 32.71 35.65 67.07 33.34 1413 1426 1537 2558.666667 1458.666667 1.21E-27 -0.823089108 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 78558 78558 'Htra3' mRNA 98 100 80 2.4 2.34 2.08 10.86 10.88 9.9 2.273333333 10.54666667 534 521 471 92.66666667 508.6666667 1.32E-53 2.447410101 GO:0005576///extracellular region GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005515///protein binding+++GO:0005520///insulin-like growth factor binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway 78560 78560 'Adgra2' mRNA 126 155 74 1.2 1.46 0.76 2.22 1.75 2.15 1.14 2.04 248 198 250 118.3333333 232 4.01E-05 0.969986659 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030175///filopodium+++GO:0042995///cell projection+++GO:1990909///Wnt signalosome GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007417///central nervous system development+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016055///Wnt signaling pathway+++GO:0043542///endothelial cell migration+++GO:0045765///regulation of angiogenesis+++GO:0050920///regulation of chemotaxis+++GO:0090210///regulation of establishment of blood-brain barrier+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway 78581 78581 'Utp23' mRNA 213.65 241.26 232.82 4.03 4.48 4.66 5.08 5.99 5.16 4.39 5.41 309.58 356.8 304.89 229.2433333 323.7566667 0.003252035 0.487013905 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome GO:0003730///mRNA 3'-UTR binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0070181///small ribosomal subunit rRNA binding "GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis" 78586 78586 'Srbd1' mRNA 248 263 292 2.28 2.59 3.06 2.5 1.99 1.88 2.643333333 2.123333333 294 246 233 267.6666667 257.6666667 0.753163157 -0.071846074 GO:0005575///cellular_component GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome GO:0006139///nucleobase-containing compound metabolic process+++GO:0006412///translation 78593 78593 'Nrip3' mRNA 193 213 245 2.67 2.89 3.59 1.44 1.92 1.61 3.05 1.656666667 120 156 130 217 135.3333333 0.001200984 -0.695745168 GO:0005575///cellular_component GO:0004190///aspartic-type endopeptidase activity GO:0006508///proteolysis+++GO:0008150///biological_process 78600 78600 'Pde6h' mRNA 2 0 0 0.28 0 0 0 0 0 0.093333333 0 0 0 0 0.666666667 0 0.749855753 -1.843955659 00230///Purine metabolism GO:0042622///photoreceptor outer segment membrane "GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0030553///cGMP binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity" GO:0000187///activation of MAPK activity+++GO:0007601///visual perception+++GO:0043410///positive regulation of MAPK cascade+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus 78610 78610 'Uvrag' mRNA 748 682 429 11.85 10.63 7.22 7.86 11 9.53 9.9 9.463333333 563 778 670 619.6666667 670.3333333 0.589584581 0.115051165 04140///Autophagy - animal "GO:0000323///lytic vacuole+++GO:0000421///autophagosome membrane+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0045335///phagocytic vesicle+++GO:0070418///DNA-dependent protein kinase complex" GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding "GO:0006281///DNA repair+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007051///spindle organization+++GO:0007059///chromosome segregation+++GO:0007098///centrosome cycle+++GO:0032465///regulation of cytokinesis+++GO:0032801///receptor catabolic process+++GO:0035493///SNARE complex assembly+++GO:0046718///viral entry into host cell+++GO:0051684///maintenance of Golgi location+++GO:0071900///regulation of protein serine/threonine kinase activity+++GO:0097352///autophagosome maturation+++GO:0097680///double-strand break repair via classical nonhomologous end joining" 78611 78611 'Btbd19' mRNA 162.48 141.92 179.9 3.09 2.72 3.56 3.55 3.73 3.91 3.123333333 3.73 209.96 214.71 224.55 161.4333333 216.4066667 0.046839588 0.408993546 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78617 78617 'Cstad' mRNA 39 31 40 3.23 2.54 3.52 2.53 4.83 2.7 3.096666667 3.353333333 35 65 36 36.66666667 45.33333333 0.574522474 0.295235788 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane GO:0003674///molecular_function GO:0007006///mitochondrial membrane organization 78618 78618 'Acap2' mRNA 870.46 914.63 855.84 5.92 6.22 6.12 8.2 8.08 8.99 6.086666667 8.423333333 1322.43 1243.85 1387.52 880.31 1317.933333 4.36E-11 0.571033391 04144///Endocytosis GO:0001726///ruffle+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane "GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0046872///metal ion binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" GO:0030029///actin filament-based process+++GO:0032456///endocytic recycling+++GO:0043547///positive regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:1990090///cellular response to nerve growth factor stimulus 78619 78619 'Zfp449' mRNA 172 165 161 2.61 2.42 2.68 1.99 2.4 2.03 2.57 2.14 156 183 156 166 165 0.943698531 -0.019018131 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007284///spermatogonial cell division 78625 78625 'Acsbg3' mRNA 3 3 2 0.07 0.06 0.04 0.2 0.11 0.11 0.056666667 0.14 11 6 6 2.666666667 7.666666667 0.219078657 1.511668382 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway GO:0005737///cytoplasm GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0016405///CoA-ligase activity GO:0042759///long-chain fatty acid biosynthetic process 78651 78651 'Lsm6' mRNA 1570.86 1598.88 1644.28 34.35 34.34 38.27 21.16 24.42 22.76 35.65333333 22.78 1140 1299.23 1196 1604.673333 1211.743333 7.09E-06 -0.416911603 03018///RNA degradation+++03040///Spliceosome GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005688///U6 snRNP+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0120115///Lsm2-8 complex GO:0003723///RNA binding+++GO:0046982///protein heterodimerization activity "GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0006402///mRNA catabolic process+++GO:0008033///tRNA processing+++GO:0008380///RNA splicing+++GO:0030490///maturation of SSU-rRNA" 78653 78653 'Bola3' mRNA 868 848 954 52.04 50.11 64.82 48.46 50.64 51.54 55.65666667 50.21333333 847 871 904 890 874 0.782061644 -0.040789828 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016604///nuclear body GO:0003674///molecular_function GO:0008150///biological_process 78655 78655 'Eif3j1' mRNA 230.78 224.71 147.79 5.35 5.12 3.63 6.02 8.35 6.8 4.7 7.056666667 298.74 405.02 326.8 201.0933333 343.52 5.91E-05 0.774775623 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex GO:0003743///translation initiation factor activity+++GO:0042802///identical protein binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation 78656 78656 'Brd8' mRNA 2623.82 2609.71 2791.93 31.74 30.92 35.42 20.7 21.17 19.27 32.69333333 20.38 1956.51 1965.13 1743.5 2675.153333 1888.38 4.98E-10 -0.516737864 GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0035267///NuA4 histone acetyltransferase complex GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046966///thyroid hormone receptor binding GO:0006325///chromatin organization+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth+++GO:0043967///histone H4 acetylation+++GO:0043968///histone H2A acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097067///cellular response to thyroid hormone stimulus 78658 78658 'Ncapd3' mRNA 589.68 542.09 521.5 5.11 4.69 4.74 4.62 4.29 3.92 4.846666667 4.276666667 601.64 533.12 494.55 551.09 543.1033333 0.850807944 -0.033203396 "GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0000779///condensed chromosome, centromeric region+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0042585///germinal vesicle" GO:0003682///chromatin binding+++GO:0035064///methylated histone binding+++GO:0042393///histone binding GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0030261///chromosome condensation+++GO:0051301///cell division+++GO:0051304///chromosome separation+++GO:0051307///meiotic chromosome separation 78670 78670 'Plekhj1' mRNA 953 960 810 46.91 46.5 42.32 41.45 46.49 43.62 45.24333333 43.85333333 977 1063 983 907.6666667 1007.666667 0.180631696 0.14271599 GO:0005769///early endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0055037///recycling endosome GO:0003674///molecular_function "GO:0001881///receptor recycling+++GO:0007032///endosome organization+++GO:0042147///retrograde transport, endosome to Golgi" 78672 78672 '9530057J20Rik' mRNA 122.8 83.04 90.93 2.63 1.75 2.07 0.5 0.43 0.36 2.15 0.43 26.71 22.58 18.87 98.92333333 22.72 5.85E-10 -2.172384785 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78688 78688 'Nol3' mRNA 73.94 42.95 77.75 1.65 0.89 1.69 2.72 2.69 3.36 1.41 2.923333333 145.74 134.82 162.56 64.88 147.7066667 2.96E-05 1.180025898 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016528///sarcoplasm+++GO:0016529///sarcoplasmic reticulum GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005102///signaling receptor binding+++GO:0005123///death receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0019902///phosphatase binding+++GO:0035877///death effector domain binding+++GO:0042802///identical protein binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0089720///caspase binding "GO:0001666///response to hypoxia+++GO:0001974///blood vessel remodeling+++GO:0002931///response to ischemia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0010664///negative regulation of striated muscle cell apoptotic process+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014736///negative regulation of muscle atrophy+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0014876///response to injury involved in regulation of muscle adaptation+++GO:0042981///regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045445///myoblast differentiation+++GO:0048659///smooth muscle cell proliferation+++GO:0051259///protein complex oligomerization+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0060547///negative regulation of necrotic cell death+++GO:0071456///cellular response to hypoxia+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0097340///inhibition of cysteine-type endopeptidase activity+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903073///negative regulation of death-inducing signaling complex assembly+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1903215///negative regulation of protein targeting to mitochondrion+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway+++GO:1990001///inhibition of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway" 78689 78689 'Naa35' mRNA 1017 916 865 21.3 18.88 19.33 15.8 15.75 16.49 19.83666667 16.01333333 872 842 873 932.6666667 862.3333333 0.251537767 -0.123606866 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005886///plasma membrane+++GO:0031417///NatC complex GO:0005515///protein binding GO:0006474///N-terminal protein amino acid acetylation+++GO:0017196///N-terminal peptidyl-methionine acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0048659///smooth muscle cell proliferation 78697 78697 'Pus7' mRNA 242 240 261 3.57 3.42 3.84 4.01 4.49 4.23 3.61 4.243333333 322 363 330 247.6666667 338.3333333 0.006755521 0.437101179 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity+++GO:0019899///enzyme binding GO:0001522///pseudouridine synthesis+++GO:0008033///tRNA processing+++GO:0009451///RNA modification+++GO:0017148///negative regulation of translation+++GO:0031119///tRNA pseudouridine synthesis+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:1990481///mRNA pseudouridine synthesis+++GO:2000380///regulation of mesoderm development 78703 78703 'Zfp972' mRNA 129.22 120.05 84.84 9.67 8.9 6.74 9.62 10.2 9.39 8.436666667 9.736666667 147.29 152.02 138.82 111.37 146.0433333 0.122099462 0.387218244 GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 78709 78709 'Spink8' mRNA 178.62 155.87 178.79 18.97 16.45 20.15 15.39 17.66 15.89 18.52333333 16.31333333 165.8 184.9 164.8 171.0933333 171.8333333 0.982802103 -0.007635593 GO:0005576///extracellular region GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity 78733 78733 'Troap' mRNA 6 7 0 0.16 0.18 0 2.58 2.19 1.8 0.113333333 2.19 119 98 81 4.333333333 99.33333333 2.41E-17 4.515190228 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007155///cell adhesion+++GO:0008150///biological_process 78748 78748 'Rassf10' mRNA 649 740 690 10.09 11.32 11.38 6.27 6.12 6.64 10.93 6.343333333 464 442 476 693 460.6666667 1.16E-07 -0.601252129 GO:0000922///spindle pole+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0050769///positive regulation of neurogenesis+++GO:2000179///positive regulation of neural precursor cell proliferation 78749 78749 'Filip1l' mRNA 98 100 90 1.63 1.64 1.6 3.71 3.7 3.84 1.623333333 3.75 255 248 256 96 253 1.15E-13 1.387580043 GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane GO:0003674///molecular_function GO:0008150///biological_process 78751 78751 'Zc3h6' mRNA 432 429 312 4.71 4.58 3.59 1.32 1.19 1.35 4.293333333 1.286666667 140 124 137 391 133.6666667 2.31E-20 -1.554753822 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003674///molecular_function+++GO:0003723///RNA binding+++GO:0046872///metal ion binding "GO:0008150///biological_process+++GO:0045892///negative regulation of transcription, DNA-templated" 78752 78752 'Csgalnact2' mRNA 365 385 261 5.25 5.5 4.04 5.2 6.92 5.71 4.93 5.943333333 405 531 434 337 456.6666667 0.009739275 0.436182397 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0047237///glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity GO:0030166///proteoglycan biosynthetic process+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0050650///chondroitin sulfate proteoglycan biosynthetic process+++GO:0050651///dermatan sulfate proteoglycan biosynthetic process 78753 78753 'Lipm' mRNA 5 9 7 0.06 0.17 0.08 0.05 0 0.04 0.103333333 0.03 3 0 2 7 1.666666667 0.139463911 -2.09070494 GO:0005575///cellular_component+++GO:0005576///extracellular region "GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds" GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process 78754 78754 'Galnt15' mRNA 135 163 116 1.31 1.54 1.11 2.19 2.21 2.09 1.32 2.163333333 247 235 239 138 240.3333333 2.42E-05 0.792947733 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle "GO:0003674///molecular_function+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding" GO:0006486///protein glycosylation+++GO:0008150///biological_process 78755 78755 'Fam122b' mRNA 459 516 497 6.81 7.27 7.67 2.97 2.69 2.75 7.25 2.803333333 231 221 220 490.6666667 224 6.30E-17 -1.144111772 GO:0005575///cellular_component+++GO:0005581///collagen trimer GO:0003674///molecular_function+++GO:0004865///protein serine/threonine phosphatase inhibitor activity GO:0008150///biological_process+++GO:0043086///negative regulation of catalytic activity 78757 78757 'Rictor' mRNA 2199 2358 2229 12.36 13.02 13.25 8.65 8.48 8.53 12.87666667 8.553333333 1771 1698 1695 2262 1721.333333 1.01E-08 -0.406193279 04150///mTOR signaling pathway GO:0031932///TORC2 complex GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0043022///ribosome binding+++GO:0043539///protein serine/threonine kinase activator activity GO:0001932///regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007275///multicellular organism development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0010468///regulation of gene expression+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0031929///TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0038203///TORC2 signaling+++GO:0042325///regulation of phosphorylation+++GO:0043087///regulation of GTPase activity+++GO:0050727///regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051896///regulation of protein kinase B signaling+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000114///regulation of establishment of cell polarity 78767 78767 'Efcab11' mRNA 24 25 20 0.66 0.68 0.58 0.86 0.83 0.37 0.64 0.686666667 36 34 15 23 28.33333333 0.664805212 0.290807194 GO:0005509///calcium ion binding+++GO:0046872///metal ion binding 78771 78771 'Mctp1' mRNA 342 344 400 3.09 3.03 3.7 1.99 1.75 1.55 3.273333333 1.763333333 258 229 197 362 228 4.84E-05 -0.68436779 GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0055037///recycling endosome GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding GO:0030336///negative regulation of cell migration+++GO:0045806///negative regulation of endocytosis+++GO:0046928///regulation of neurotransmitter secretion+++GO:1902883///negative regulation of response to oxidative stress 78772 78772 'Hhipl2' mRNA 6 5 5 0.12 0.1 0.1 0.08 0.14 0.21 0.106666667 0.143333333 4 8 11 5.333333333 7.666666667 0.680686357 0.518135995 GO:0005575///cellular_component+++GO:0005576///extracellular region GO:0003674///molecular_function+++GO:0003824///catalytic activity GO:0008150///biological_process 78774 78774 'Cfap61' mRNA 610 647 510 9.48 10.26 8.96 1.27 0.88 1.1 9.566666667 1.083333333 68 44 72 589 61.33333333 1.10E-75 -3.272623798 GO:0001536///radial spoke stalk+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0003674///molecular_function GO:0003341///cilium movement+++GO:0008150///biological_process+++GO:0044782///cilium organization 78777 78777 'Tepsin' mRNA 500 544 493 9.94 10.58 10.39 11.68 10.47 11.6 10.30333333 11.25 676 593 650 512.3333333 639.6666667 0.007442898 0.308416113 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0030124///AP-4 adaptor complex+++GO:0030662///coated vesicle membrane+++GO:0031312///extrinsic component of organelle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031965///nuclear membrane+++GO:0032588///trans-Golgi network membrane GO:0003674///molecular_function GO:0008150///biological_process 78779 78779 'Spata2l' mRNA 672 650 619 14.8 14.45 14.17 7.06 6 6.47 14.47333333 6.51 366 315 323 647 334.6666667 1.75E-16 -0.963281956 04217///Necroptosis GO:0005737///cytoplasm GO:0003674///molecular_function GO:0008150///biological_process 78781 78781 'Zc3hav1' mRNA 1223.88 1126.77 1305.79 12.69 11.45 14.44 30.42 30.08 29.21 12.86 29.90333333 3304.87 3225.74 3079.67 1218.813333 3203.426667 3.34E-60 1.379333092 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005829///cytosol GO:0003723///RNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:1990404///protein ADP-ribosylase activity GO:0002376///immune system process+++GO:0006471///protein ADP-ribosylation+++GO:0009615///response to virus+++GO:0032481///positive regulation of type I interferon production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032781///positive regulation of ATPase activity+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0050691///regulation of defense response to virus by host+++GO:0051607///defense response to virus+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0071360///cellular response to exogenous dsRNA+++GO:0098586///cellular response to virus+++GO:1900246///positive regulation of RIG-I signaling pathway 78783 78783 'Brpf1' mRNA 390 442 298 4.49 5.04 3.65 4.82 3.76 4.62 4.393333333 4.4 478 367 447 376.6666667 430.6666667 0.288006876 0.186302268 GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0070776///MOZ/MORF histone acetyltransferase complex GO:0003677///DNA binding+++GO:0010698///acetyltransferase activator activity+++GO:0042393///histone binding+++GO:0046872///metal ion binding "GO:0001570///vasculogenesis+++GO:0001841///neural tube formation+++GO:0006325///chromatin organization+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0043966///histone H3 acetylation+++GO:0043972///histone H3-K23 acetylation+++GO:0044154///histone H3-K14 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048145///regulation of fibroblast proliferation+++GO:0050790///regulation of catalytic activity" 78784 78784 'Celf3' mRNA 141.76 138.6 132.97 1.02 1.03 0.93 0.72 0.58 0.41 0.993333333 0.57 99.86 80.19 67.11 137.7766667 82.38666667 0.002625946 -0.753863305 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0097322///7SK snRNA binding "GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006376///mRNA splice site selection+++GO:0006397///mRNA processing+++GO:0007283///spermatogenesis+++GO:0008380///RNA splicing+++GO:0030317///flagellated sperm motility+++GO:0030575///nuclear body organization+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0098781///ncRNA transcription" 78785 78785 'Clip4' mRNA 365 356 329 6.3 5.52 6.1 1.79 1.96 2.01 5.973333333 1.92 151 146 147 350 148 1.25E-15 -1.252488457 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0035371///microtubule plus-end+++GO:0043231///intracellular membrane-bounded organelle GO:0051010///microtubule plus-end binding GO:0031122///cytoplasmic microtubule organization 78787 78787 'Usp54' mRNA 2141 2187.01 1985 15.24 15.51 15.33 8.98 8.33 7.77 15.36 8.36 1515 1354 1255 2104.336667 1374.666667 1.57E-15 -0.62592266 GO:0005575///cellular_component GO:0004843///thiol-dependent ubiquitin-specific protease activity GO:0008150///biological_process+++GO:0016579///protein deubiquitination 78795 78795 'Armc9' mRNA 799.83 875.73 818.09 8.92 9.84 10.65 5.77 5.23 5.11 9.803333333 5.37 475.63 436.82 459.6 831.2166667 457.35 5.07E-17 -0.87536554 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097542///ciliary tip GO:0003674///molecular_function GO:0030030///cell projection organization+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060271///cilium assembly 78796 78796 'Zcchc4' mRNA 392.15 367.67 389.14 4.75 5.13 5.49 4.58 3.88 4.5 5.123333333 4.32 353.86 314.9 335.68 382.9866667 334.8133333 0.169108699 -0.21014333 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0008988///rRNA (adenine-N6-)-methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:1904047///S-adenosyl-L-methionine binding GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0045727///positive regulation of translation 78797 78797 'Ndor1' mRNA 925 886 917 10.95 10.15 11.36 7.93 7.93 8.28 10.82 8.046666667 782 777 805 909.3333333 788 0.03334706 -0.219363507 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0048471///perinuclear region of cytoplasm "GO:0003958///NADPH-hemoprotein reductase activity+++GO:0008753///NADPH dehydrogenase (quinone) activity+++GO:0009055///electron transfer activity+++GO:0010181///FMN binding+++GO:0016491///oxidoreductase activity+++GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0016653///oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0016731///oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0070402///NADPH binding+++GO:0071949///FAD binding" GO:0008219///cell death+++GO:0016226///iron-sulfur cluster assembly+++GO:0016567///protein ubiquitination+++GO:0022900///electron transport chain+++GO:0036245///cellular response to menadione 78798 78798 'Eml4' mRNA 498 558 384 5.09 5.68 4.54 4.68 4.1 4.42 5.103333333 4.4 500 429 470 480 466.3333333 0.800369356 -0.048148616 05200///Pathways in cancer+++05223///Non-small cell lung cancer+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody+++GO:0072686///mitotic spindle GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0048487///beta-tubulin binding GO:0000226///microtubule cytoskeleton organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0051301///cell division 78801 78801 'Ak7' mRNA 15 20 13 0.21 0.33 0.24 0.14 0.03 0.15 0.26 0.106666667 11 2 11 16 8 0.242440592 -1.012198187 00230///Purine metabolism+++00730///Thiamine metabolism+++01240///Biosynthesis of cofactors GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0031514///motile cilium+++GO:0042995///cell projection GO:0000166///nucleotide binding+++GO:0004017///adenylate kinase activity+++GO:0004127///cytidylate kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019205///nucleobase-containing compound kinase activity GO:0002437///inflammatory response to antigenic stimulus+++GO:0003351///epithelial cilium movement+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0016310///phosphorylation+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0046940///nucleoside monophosphate phosphorylation 78802 78802 'Ttc30a1' mRNA 436.27 415.78 454.43 8.4 7.88 9.28 3.42 3.13 4.09 8.52 3.546666667 204.12 182.63 236.85 435.4933333 207.8666667 1.99E-12 -1.083571243 GO:0005813///centrosome+++GO:0005879///axonemal microtubule+++GO:0005929///cilium+++GO:0030992///intraciliary transport particle B+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0120170///intraciliary transport particle B binding GO:0030030///cell projection organization+++GO:0035720///intraciliary anterograde transport+++GO:0042073///intraciliary transport 78803 78803 'Fbxo43' mRNA 8.99 9.89 7.01 0.12 0.14 0.09 0.23 0.26 0.3 0.116666667 0.263333333 18.9 20.67 23.74 8.63 21.10333333 0.055116133 1.338465368 04114///Oocyte meiosis GO:0005634///nucleus GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0040020///regulation of meiotic nuclear division+++GO:0042177///negative regulation of protein catabolic process+++GO:0045835///negative regulation of meiotic nuclear division+++GO:0051321///meiotic cell cycle 78806 78806 'Stpg1' mRNA 181.58 146.55 101.2 3.4 2.58 1.91 0.99 0.58 0.87 2.63 0.813333333 59 35 50.06 143.11 48.02 9.57E-08 -1.577855053 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process 78808 78808 'Stxbp5' mRNA 369 395 364 2.6 2.66 2.6 1.61 1.62 2.16 2.62 1.796666667 261 253 325 376 279.6666667 0.005360856 -0.437867557 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030141///secretory granule+++GO:0031201///SNARE complex+++GO:0031594///neuromuscular junction+++GO:0098674///extrinsic component of neuronal dense core vesicle membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098793///presynapse+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0099523///presynaptic cytosol GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0045159///myosin II binding GO:0006887///exocytosis+++GO:0007409///axonogenesis+++GO:0010807///regulation of synaptic vesicle priming+++GO:0015031///protein transport+++GO:0017157///regulation of exocytosis+++GO:0045921///positive regulation of exocytosis+++GO:0050708///regulation of protein secretion+++GO:0050790///regulation of catalytic activity+++GO:0099504///synaptic vesicle cycle+++GO:2000300///regulation of synaptic vesicle exocytosis 78809 78809 '4930562C15Rik' mRNA 8 9 6 0.12 0.13 0.09 0.04 0.09 0.05 0.113333333 0.06 3 7 4 7.666666667 4.666666667 0.556707138 -0.715751293 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 78816 78816 'Gmip' mRNA 224.01 253.82 225.01 3.23 3.64 3.44 8.62 8.17 8.46 3.436666667 8.416666667 699.71 649.37 669.38 234.28 672.82 1.94E-35 1.511395055 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding GO:0007165///signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0090630///activation of GTPase activity 78825 78825 'Desi2' mRNA 411.28 428.55 210.67 5.15 5.35 2.74 3.68 3.43 3.97 4.413333333 3.693333333 341.7 304 353.84 350.1666667 333.18 0.802816782 -0.070409083 GO:0005737///cytoplasm GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990380///Lys48-specific deubiquitinase activity GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0070646///protein modification by small protein removal+++GO:0071108///protein K48-linked deubiquitination 78826 78826 'P2ry10' mRNA 0 2 2 0 0.04 0.04 0.19 0.23 0.26 0.026666667 0.226666667 11 13 15.13 1.333333333 13.04333333 0.005189822 3.270672991 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 78829 78829 'Tsc22d4' mRNA 3534 3506 3044 84.24 82.29 76.98 99.53 101.49 102.49 81.17 101.17 4801 4780 4786 3361.333333 4789 1.17E-17 0.501571753 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006970///response to osmotic stress 78830 78830 'Slc25a12' mRNA 2399 2541 2254 40.78 41.46 40.79 28.08 28.13 29.07 41.01 28.42666667 1923 1854 1918 2398 1898.333333 2.13E-07 -0.347514592 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043209///myelin sheath GO:0005313///L-glutamate transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0015183///L-aspartate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006537///glutamate biosynthetic process+++GO:0006810///transport+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0010907///positive regulation of glucose metabolic process+++GO:0015810///aspartate transmembrane transport+++GO:0015813///L-glutamate transmembrane transport+++GO:0031643///positive regulation of myelination+++GO:0043490///malate-aspartate shuttle+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0070778///L-aspartate transmembrane transport+++GO:1904024///negative regulation of glucose catabolic process to lactate via pyruvate+++GO:2001171///positive regulation of ATP biosynthetic process 78832 78832 'Cacul1' mRNA 867 852 709 7.62 7.41 6.63 8.42 8.97 9.25 7.22 8.88 1087 1119 1150 809.3333333 1118.666667 1.21E-06 0.459010577 GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0045860///positive regulation of protein kinase activity 78833 78833 'Gins3' mRNA 103 114 97 2.39 2.6 2.38 3.04 3.16 3.97 2.456666667 3.39 151 153 191 104.6666667 165 0.004447043 0.647540149 GO:0000811///GINS complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0071162///CMG complex GO:0003674///molecular_function GO:0006260///DNA replication+++GO:1902975///mitotic DNA replication initiation 78834 78834 'Zfp623' mRNA 420 454 448 9.28 9.87 10.64 8.14 9.69 8.15 9.93 8.66 420 494 411 440.6666667 441.6666667 0.967697917 -0.008205843 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific" GO:0006357///regulation of transcription by RNA polymerase II 78885 78885 'Coro7' mRNA 575 510 562 8.97 7.82 9.3 17.41 16.76 16.32 8.696666667 16.83 1285 1208 1166 549 1219.666667 1.45E-30 1.137693501 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0006895///Golgi to endosome transport+++GO:0007015///actin filament organization+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:0016477///cell migration+++GO:0030010///establishment of cell polarity+++GO:0030041///actin filament polymerization 78887 78887 'Sfi1' mRNA 1410.4 1378.95 1252.66 14.97 14.28 13.83 11.68 9.74 10.82 14.36 10.74666667 1227.19 1001.89 1106.28 1347.336667 1111.786667 0.001523585 -0.288879061 GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005856///cytoskeleton GO:0019902///phosphatase binding GO:0010923///negative regulation of phosphatase activity 78889 78889 'Wsb1' mRNA 2101 2176 2061 45.29 46.23 47.12 59.46 53.89 54.6 46.21333333 55.98333333 3171 2780 2808 2112.666667 2919.666667 5.38E-11 0.453955426 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0044314///protein K27-linked ubiquitination 78890 78890 'Trmt44' mRNA 259 239 280 4.09 3.6 4.63 2.41 2.64 3.25 4.106666667 2.766666667 180 192 233 259.3333333 201.6666667 0.054381345 -0.377157764 GO:0005575///cellular_component+++GO:0005737///cytoplasm GO:0008168///methyltransferase activity+++GO:0016300///tRNA (uracil) methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0052665///tRNA (uracil-2'-O-)-methyltransferase activity GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation 78891 78891 'Scyl1' mRNA 2290 2375 2113 47.99 48.98 46.94 37.63 39.79 39.08 47.97 38.83333333 2069.58 2138.66 2081 2259.333333 2096.413333 0.117169507 -0.118029953 GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030126///COPI vesicle coat GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding "GO:0006468///protein phosphorylation+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006954///inflammatory response+++GO:0016192///vesicle-mediated transport+++GO:0021522///spinal cord motor neuron differentiation+++GO:0034613///cellular protein localization+++GO:0048666///neuron development" 78892 78892 'Crispld2' mRNA 343 381 370 4.42 4.82 5.05 2.46 2.64 2.36 4.763333333 2.486666667 220 231 203 364.6666667 218 8.10E-07 -0.75461522 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030133///transport vesicle+++GO:0031012///extracellular matrix GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding GO:0030198///extracellular matrix organization+++GO:0030324///lung development+++GO:0060325///face morphogenesis 78893 78893 'Cnot10' mRNA 1441 1458 1432 27.75 27.72 29.2 17.91 18.61 17.05 28.22333333 17.85666667 1068 1088 984 1443.666667 1046.666667 2.46E-08 -0.476072035 03018///RNA degradation GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex GO:0003674///molecular_function GO:0006402///mRNA catabolic process+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0031047///gene silencing by RNA 78894 78894 'Aacs' mRNA 1659 1779 1819 28.59 30.17 33.25 14.24 14.03 12.99 30.67 13.75333333 951 915 840 1752.333333 902 2.90E-27 -0.972314427 "00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism" GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0030729///acetoacetate-CoA ligase activity+++GO:0047760///butyrate-CoA ligase activity GO:0001889///liver development+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007584///response to nutrient+++GO:0009410///response to xenobiotic stimulus+++GO:0010243///response to organonitrogen compound+++GO:0014070///response to organic cyclic compound+++GO:0014074///response to purine-containing compound+++GO:0032024///positive regulation of insulin secretion+++GO:0034201///response to oleic acid+++GO:0042493///response to drug+++GO:0042594///response to starvation+++GO:0045471///response to ethanol+++GO:0050872///white fat cell differentiation+++GO:0060612///adipose tissue development+++GO:0071333///cellular response to glucose stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0071397///cellular response to cholesterol 78895 78895 'Pus7l' mRNA 58 31 34 1.23 0.59 0.7 1.35 1.76 1.29 0.84 1.466666667 80 101 74 41 85 0.003359594 1.044709128 GO:0005634///nucleus GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity+++GO:0016853///isomerase activity GO:0001522///pseudouridine synthesis+++GO:0009451///RNA modification 78896 78896 'Ecrg4' mRNA 1621 1682 1656 120.44 123.73 130.57 83.15 89.28 85.75 124.9133333 86.06 1282 1341 1277 1653 1300 1.24E-05 -0.358630001 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0031045///dense core granule GO:0005184///neuropeptide hormone activity GO:0007218///neuropeptide signaling pathway+++GO:0007417///central nervous system development+++GO:0008285///negative regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0030103///vasopressin secretion+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0042127///regulation of cell proliferation+++GO:0051461///positive regulation of corticotropin secretion+++GO:0051466///positive regulation of corticotropin-releasing hormone secretion+++GO:0070314///G1 to G0 transition+++GO:0090398///cellular senescence+++GO:2000854///positive regulation of corticosterone secretion 78903 78903 'Wrnip1' mRNA 943 946 173 19.79 19.55 3.85 3.34 5.53 8.61 14.39666667 5.826666667 183 296 457 687.3333333 312 0.21025141 -1.115816834 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm" GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008047///enzyme activator activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017116///single-stranded DNA-dependent ATP-dependent DNA helicase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0000731///DNA synthesis involved in DNA repair+++GO:0002376///immune system process+++GO:0006260///DNA replication+++GO:0006261///DNA-dependent DNA replication+++GO:0006281///DNA repair+++GO:0006282///regulation of DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030174///regulation of DNA-dependent DNA replication initiation+++GO:0032508///DNA duplex unwinding+++GO:0045087///innate immune response+++GO:0050790///regulation of catalytic activity 78906 78906 'Misp' mRNA 931 969 907 20.94 21.52 21.73 10.33 11.31 10.93 21.39666667 10.85666667 528 560 535 935.6666667 541 4.07E-16 -0.801195286 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:1905721///mitotic spindle astral microtubule end GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0000132///establishment of mitotic spindle orientation+++GO:0007049///cell cycle+++GO:0016477///cell migration+++GO:0051301///cell division+++GO:0051640///organelle localization+++GO:0051660///establishment of centrosome localization+++GO:0090307///mitotic spindle assembly+++GO:1904776///regulation of protein localization to cell cortex 78908 78908 'Igsf3' mRNA 1690 1675 1852 12.13 11.81 14.11 9.36 9.36 9.93 12.68333333 9.55 1506 1467 1544 1739 1505.666667 0.017583678 -0.222877861 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0032808///lacrimal gland development 78910 78910 'Asb15' mRNA 2 0 0 0.03 0 0 0.01 0.06 0.05 0.01 0.04 1 5 4 0.666666667 3.333333333 0.307379952 2.33672079 GO:0005515///protein binding GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction 78911 78911 'Trim42' mRNA 0 0 1 0 0 0.02 0 0 0 0.006666667 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0000785///chromatin+++GO:0005654///nucleoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding "GO:0016567///protein ubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated" 78912 78912 'Sp2' mRNA 762 771 553 13.77 13.67 10.6 9.28 8.52 8.95 12.68 8.916666667 591 530 553 695.3333333 558 0.011537222 -0.323627414 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035264///multicellular organism growth+++GO:0048144///fibroblast proliferation+++GO:0048568///embryonic organ development+++GO:0072359///circulatory system development 78913 78913 'Ltn1' mRNA 1006 882 949 6.7 5.84 6.78 6.06 5.84 5.32 6.44 5.74 1030 973 880 945.6666667 961 0.946349973 0.009504658 GO:0005829///cytosol+++GO:1990112///RQC complex GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0043023///ribosomal large subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0072344///rescue of stalled ribosome+++GO:1990116///ribosome-associated ubiquitin-dependent protein catabolic process 78914 78914 'Nadsyn1' mRNA 282 309 237 6.64 7.02 5.57 4.51 3.93 4.44 6.41 4.293333333 220 173 218 276 203.6666667 0.012607804 -0.447439606 00760///Nicotinate and nicotinamide metabolism+++01240///Biosynthesis of cofactors GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003952///NAD+ synthase (glutamine-hydrolyzing) activity+++GO:0004359///glutaminase activity+++GO:0005524///ATP binding+++GO:0008795///NAD+ synthase activity+++GO:0016874///ligase activity GO:0006807///nitrogen compound metabolic process+++GO:0009435///NAD biosynthetic process+++GO:0034627///'de novo' NAD biosynthetic process 78919 78919 'Fndc8' mRNA 1 2 0 0.03 0.05 0 0 0.05 0.05 0.026666667 0.033333333 0 2 2 1 1.333333333 0.881313794 0.448644199 GO:0003674///molecular_function GO:0008150///biological_process 78920 78920 'Dlst' mRNA 1819 1969 1966 36.32 38.7 41.64 46.95 43.56 45.83 38.88666667 45.44666667 2705 2451 2557 1918 2571 8.13E-08 0.408737343 00020///Citrate cycle (TCA cycle)+++00310///Lysine degradation+++00380///Tryptophan metabolism+++01200///Carbon metabolism GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0034451///centriolar satellite+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045252///oxoglutarate dehydrogenase complex "GO:0004149///dihydrolipoyllysine-residue succinyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0031072///heat shock protein binding+++GO:0051087///chaperone binding" GO:0006099///tricarboxylic acid cycle+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0006734///NADH metabolic process+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0106077///histone succinylation 78921 78921 '9130019O22Rik' mRNA 232.63 243.67 274.41 3.24 3.34 4.06 3.6 3.63 2.9 3.546666667 3.376666667 297.01 292.51 232.02 250.2366667 273.8466667 0.600942635 0.116446058 05168///Herpes simplex virus 1 infection GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 78923 78923 'Chsy3' mRNA 27 58 18 0.38 0.79 0.27 0.16 0.35 0.21 0.48 0.24 13 28 17 34.33333333 19.33333333 0.191446479 -0.815949587 00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0050510///N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity GO:0030206///chondroitin sulfate biosynthetic process 78925 78925 'Srd5a1' mRNA 532 549 543 11.06 11.44 12.53 3.31 3.04 3.3 11.67666667 3.216666667 170 146 177 541.3333333 164.3333333 1.21E-34 -1.733139781 00140///Steroid hormone biosynthesis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070852///cell body fiber "GO:0003865///3-oxo-5-alpha-steroid 4-dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0033218///amide binding+++GO:0047751///cholestenone 5-alpha-reductase activity+++GO:0050213///progesterone 5-alpha-reductase activity+++GO:0070402///NADPH binding" "GO:0001655///urogenital system development+++GO:0001889///liver development+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0006710///androgen catabolic process+++GO:0007548///sex differentiation+++GO:0008202///steroid metabolic process+++GO:0008209///androgen metabolic process+++GO:0008584///male gonad development+++GO:0009267///cellular response to starvation+++GO:0009410///response to xenobiotic stimulus+++GO:0014070///response to organic cyclic compound+++GO:0014850///response to muscle activity+++GO:0016101///diterpenoid metabolic process+++GO:0021510///spinal cord development+++GO:0021766///hippocampus development+++GO:0021794///thalamus development+++GO:0021854///hypothalamus development+++GO:0021983///pituitary gland development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030539///male genitalia development+++GO:0030540///female genitalia development+++GO:0032354///response to follicle-stimulating hormone+++GO:0032355///response to estradiol+++GO:0032869///cellular response to insulin stimulus+++GO:0033574///response to testosterone+++GO:0042428///serotonin metabolic process+++GO:0042448///progesterone metabolic process+++GO:0042493///response to drug+++GO:0042747///circadian sleep/wake cycle, REM sleep+++GO:0043627///response to estrogen+++GO:0060348///bone development+++GO:0060416///response to growth hormone+++GO:0060992///response to fungicide+++GO:0071320///cellular response to cAMP+++GO:0071363///cellular response to growth factor stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:0071394///cellular response to testosterone stimulus+++GO:0071407///cellular response to organic cyclic compound+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071872///cellular response to epinephrine stimulus" 78926 78926 'Gas2l1' mRNA 399 422 99 8.43 8.6 2.13 3.48 10.34 8.27 6.386666667 7.363333333 192 555 440 306.6666667 395.6666667 0.693428997 0.392702155 GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005884///actin filament+++GO:0035371///microtubule plus-end GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0046966///thyroid hormone receptor binding+++GO:0051015///actin filament binding GO:0000226///microtubule cytoskeleton organization+++GO:0001578///microtubule bundle formation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007050///cell cycle arrest+++GO:0009267///cellular response to starvation+++GO:0010629///negative regulation of gene expression+++GO:0030308///negative regulation of cell growth+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0051726///regulation of cell cycle+++GO:0051764///actin crosslink formation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:1904825///protein localization to microtubule plus-end 78928 78928 'Pigt' mRNA 3250 3099 2606 99.04 93.7 86.78 91.88 105.8 100.25 93.17333333 99.31 3438 3783 3636 2985 3619 5.39E-04 0.270854105 00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042765///GPI-anchor transamidase complex GO:0006506///GPI anchor biosynthetic process+++GO:0016255///attachment of GPI anchor to protein+++GO:0030182///neuron differentiation+++GO:0051402///neuron apoptotic process 78929 78929 'Polr3h' mRNA 1368.59 1676.36 1524.86 29.54 35.88 35.48 20.07 21.45 21.65 33.63333333 21.05666667 1059.99 1109.97 1108.11 1523.27 1092.69 2.68E-07 -0.49106083 03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity "GO:0002376///immune system process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006351///transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0006383///transcription by RNA polymerase III+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0045087///innate immune response+++GO:0051607///defense response to virus" 78933 78933 'Agbl4' mRNA 137 170 192 4.15 4.68 5.09 0.33 0.18 0.18 4.64 0.23 10 9 8 166.3333333 9 8.13E-29 -4.22604743 04361///Axon regeneration GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030424///axon+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:1904115///axon cytoplasm GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0015631///tubulin binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0008285///negative regulation of cell proliferation+++GO:0021954///central nervous system neuron development+++GO:0035608///protein deglutamylation+++GO:0035609///C-terminal protein deglutamylation+++GO:0035610///protein side chain deglutamylation+++GO:0051607///defense response to virus+++GO:0098930///axonal transport+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0098958///retrograde axonal transport of mitochondrion+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 78935 78935 'Saal1' mRNA 320 365 302 5.96 6.27 6.87 6.01 6.96 5.63 6.366666667 6.2 339 364 308 329 337 0.891348994 0.02573379 GO:0005581///collagen trimer+++GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:1901647///positive regulation of synoviocyte proliferation 78937 78937 'Avl9' mRNA 790 797 653 6.23 6.18 5.46 4.33 3.81 4.03 5.956666667 4.056666667 631 544 571 746.6666667 582 8.57E-04 -0.368822059 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0055037///recycling endosome GO:0003674///molecular_function GO:0016477///cell migration 78938 78938 'Fbxo34' mRNA 515 546 531 9.21 9.6 10.18 9.28 7.88 9.28 9.663333333 8.813333333 594 486 573 530.6666667 551 0.810710156 0.040594754 GO:0003674///molecular_function GO:0008150///biological_process 78943 78943 'Ern1' mRNA 425 379 333 3.44 3.14 2.93 3.06 3.06 3.2 3.17 3.106666667 432 424 442 379 432.6666667 0.220484022 0.182211288 04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05017///Spinocerebellar ataxia+++05022///Pathways of neurodegeneration - multiple diseases+++05417///Lipid and atherosclerosis GO:0005637///nuclear inner membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:1990597///AIP1-IRE1 complex+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:1990630///IRE1-RACK1-PP2A complex GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003824///catalytic activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019899///enzyme binding+++GO:0030544///Hsp70 protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043531///ADP binding+++GO:0046872///metal ion binding+++GO:0051082///unfolded protein binding+++GO:0051879///Hsp90 protein binding "GO:0001935///endothelial cell proliferation+++GO:0006379///mRNA cleavage+++GO:0006397///mRNA processing+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0006986///response to unfolded protein+++GO:0007050///cell cycle arrest+++GO:0007257///activation of JUN kinase activity+++GO:0008152///metabolic process+++GO:0016310///phosphorylation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0033120///positive regulation of RNA splicing+++GO:0034620///cellular response to unfolded protein+++GO:0034976///response to endoplasmic reticulum stress+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046777///protein autophosphorylation+++GO:0051726///regulation of cell cycle+++GO:0070054///mRNA splicing, via endonucleolytic cleavage and ligation+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071333///cellular response to glucose stimulus+++GO:0098787///mRNA cleavage involved in mRNA processing+++GO:1900103///positive regulation of endoplasmic reticulum unfolded protein response+++GO:1901142///insulin metabolic process+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:1990579///peptidyl-serine trans-autophosphorylation" 78977 78977 'Popdc3' mRNA 519.94 552.41 536 17.12 17.84 18.19 1.75 1.14 1.51 17.71666667 1.466666667 58 40 52 536.1166667 50 7.23E-80 -3.435178953 GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma GO:0000166///nucleotide binding+++GO:0030552///cAMP binding GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0042391///regulation of membrane potential+++GO:0051146///striated muscle cell differentiation 79043 79043 'Spsb3' mRNA 1259 1292 1227 42.72 43.02 43.96 34.31 33.83 33.57 43.23333333 33.90333333 1153 1111 1103 1259.333333 1122.333333 0.040257813 -0.177928151 GO:0019005///SCF ubiquitin ligase complex GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process 79044 79044 'Mrps34' mRNA 816 752 737 58.43 53.3 56 54.25 61.32 54.79 55.91 56.78666667 868 956 847 768.3333333 890.3333333 0.066961438 0.202091394 GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0032543///mitochondrial translation 79059 79059 'Nme3' mRNA 1003 930 950 97.73 89.94 98.24 74.82 71.36 74.09 95.30333333 73.42333333 878 815 839 961 844 0.045953531 -0.200111706 00230///Purine metabolism+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion GO:0000166///nucleotide binding+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006228///UTP biosynthetic process+++GO:0006231///dTMP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0016310///phosphorylation 791260 791260 'Tomt' mRNA 2571.96 2675.78 2595.37 154.75 156.62 163.63 18.89 18.91 17.77 158.3333333 18.52333333 348.57 336.12 312.76 2614.37 332.4833333 2.86E-262 -2.989426113 00140///Steroid hormone biosynthesis+++00350///Tyrosine metabolism+++04728///Dopaminergic synapse GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0045177///apical part of cell GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008171///O-methyltransferase activity+++GO:0016206///catechol O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0102084///L-dopa O-methyltransferase activity+++GO:0102938///orcinol O-methyltransferase activity GO:0006584///catecholamine metabolic process+++GO:0007605///sensory perception of sound+++GO:0032259///methylation+++GO:0032502///developmental process+++GO:0042135///neurotransmitter catabolic process+++GO:0042417///dopamine metabolic process+++GO:0042424///catecholamine catabolic process+++GO:0060117///auditory receptor cell development+++GO:1904591///positive regulation of protein import 791303 791303 'Gm10277' mRNA 153.4 120.48 149.12 2.61 2.02 2.69 2.22 2.11 2.01 2.44 2.113333333 150.3 139.17 131.4 141 140.29 0.939941895 -0.022422406 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 791312 791312 'Gm9997' mRNA 31 29 19 0.69 0.64 0.45 0.06 0.04 0.08 0.593333333 0.06 3 2 4 26.33333333 3 5.36E-05 -3.137879159 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 791415 791415 'Gm12500' mRNA 56.87 41.63 58.9 1.59 1.14 1.74 1.02 1.07 0.62 1.49 0.903333333 41.84 43.18 24.89 52.46666667 36.63666667 0.229363718 -0.53894857 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 79196 79196 'Osbpl5' mRNA 1023 1034 1053 14.53 14.5 15.97 12.74 11.15 11.83 15 11.90666667 1028 875 926 1036.666667 943 0.15390948 -0.150936131 04979///Cholesterol metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0097440///apical dendrite GO:0001786///phosphatidylserine binding+++GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0070273///phosphatidylinositol-4-phosphate binding GO:0006869///lipid transport+++GO:0007286///spermatid development+++GO:0015914///phospholipid transport+++GO:0015918///sterol transport+++GO:0120009///intermembrane lipid transfer 79201 79201 'Tnfrsf23' mRNA 28.79 43.12 31.94 0.48 0.7 0.56 5.85 5.6 6.04 0.58 5.83 405.06 371.38 387.92 34.61666667 388.12 3.61E-60 3.501040649 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031265///CD95 death-inducing signaling complex+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding GO:0006924///activation-induced cell death of T cells+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0097049///motor neuron apoptotic process+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097527///necroptotic signaling pathway+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 79202 79202 'Tnfrsf22' mRNA 159.49 187.83 136.45 2.18 2.48 1.92 3.7 3.69 3.18 2.193333333 3.523333333 326.72 314.71 266.94 161.2566667 302.79 2.94E-07 0.902608021 GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0002020///protease binding+++GO:0003676///nucleic acid binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0045569///TRAIL binding "GO:0036462///TRAIL-activated apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" 79221 79221 'Hdac9' mRNA 350.01 398.4 285.01 3.92 4.21 3.45 2.5 2.66 2.63 3.86 2.596666667 270.01 250 265.03 344.4733333 261.68 0.011970666 -0.402887881 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033558///protein deacetylase activity+++GO:0034739///histone deacetylase activity (H4-K16 specific)+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0070491///repressing transcription factor binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001818///negative regulation of cytokine production+++GO:0001975///response to amphetamine+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006954///inflammatory response+++GO:0007399///nervous system development+++GO:0007507///heart development+++GO:0008340///determination of adult lifespan+++GO:0016575///histone deacetylation+++GO:0030182///neuron differentiation+++GO:0030183///B cell differentiation+++GO:0032869///cellular response to insulin stimulus+++GO:0034983///peptidyl-lysine deacetylation+++GO:0042113///B cell activation+++GO:0042632///cholesterol homeostasis+++GO:0045843///negative regulation of striated muscle tissue development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051005///negative regulation of lipoprotein lipase activity+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0070932///histone H3 deacetylation+++GO:0070933///histone H4 deacetylation+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1990678///histone H4-K16 deacetylation" 79233 79233 'Zfp319' mRNA 455.01 458.76 386.8 6.18 6.13 5.58 5.07 4.8 4.75 5.963333333 4.873333333 429.14 397.37 389.18 433.5233333 405.23 0.492103257 -0.105986696 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II 79235 79235 'Lrat' mRNA 46 43 32 0.46 0.42 0.34 0.11 0.2 0.29 0.406666667 0.2 13 23 32 40.33333333 22.66666667 0.10403683 -0.832767936 00830///Retinol metabolism+++04977///Vitamin digestion and absorption GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm "GO:0001972///retinoic acid binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019841///retinol binding+++GO:0047173///phosphatidylcholine-retinol O-acyltransferase activity+++GO:0102279///lecithin:11-cis retinol acyltransferase activity" "GO:0006653///1,2-diacyl-sn-glycero-3-phosphocholine metabolic process+++GO:0006776///vitamin A metabolic process+++GO:0007601///visual perception+++GO:0009617///response to bacterium+++GO:0009790///embryo development+++GO:0032370///positive regulation of lipid transport+++GO:0032526///response to retinoic acid+++GO:0033189///response to vitamin A+++GO:0042572///retinol metabolic process+++GO:0050896///response to stimulus+++GO:1990830///cellular response to leukemia inhibitory factor" 79263 79263 'Trim39' mRNA 601 699 586 11.96 12.96 12.24 6.88 7.23 8.61 12.38666667 7.573333333 397 422 486 628.6666667 435 2.33E-05 -0.540063492 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0006915///apoptotic process+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0050821///protein stabilization+++GO:1902806///regulation of cell cycle G1/S phase transition+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:2001235///positive regulation of apoptotic signaling pathway 79264 79264 'Krit1' mRNA 675 701 667 6.04 6.17 6.33 5.8 6.04 5.77 6.18 5.87 745 754 722 681 740.3333333 0.355302547 0.109045103 04015///Rap1 signaling pathway+++04212///Longevity regulating pathway - worm GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex "GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008017///microtubule binding+++GO:0030695///GTPase regulator activity" GO:0001525///angiogenesis+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0010596///negative regulation of endothelial cell migration+++GO:0016525///negative regulation of angiogenesis+++GO:0032092///positive regulation of protein binding+++GO:0045454///cell redox homeostasis+++GO:0050790///regulation of catalytic activity+++GO:2000114///regulation of establishment of cell polarity+++GO:2000352///negative regulation of endothelial cell apoptotic process 79362 79362 'Bhlhe41' mRNA 2571 2396 2335 22.69 20.79 21.91 29.35 28.35 28.75 21.79666667 28.81666667 3819 3605 3624 2434 3682.666667 9.99E-21 0.585645113 04710///Circadian rhythm GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043425///bHLH transcription factor binding+++GO:0043426///MRF binding+++GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007623///circadian rhythm+++GO:0009952///anterior/posterior pattern specification+++GO:0010832///negative regulation of myotube differentiation+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0032922///circadian regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis" 79401 79401 'Spz1' mRNA 0 2 0 0 0.07 0 0 0 0 0.023333333 0 0 0 0 0.666666667 0 0.750387006 -1.824848553 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity "GO:0006355///regulation of transcription, DNA-templated" 79455 79455 'Pdcl2' mRNA 0 0 2 0 0 0.12 0 0 0 0.04 0 0 0 0 0.666666667 0 0.739263611 -1.940179449 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 79456 79456 'Recql4' mRNA 22.09 28.17 21.14 0.29 0.38 0.31 0.58 0.55 0.48 0.326666667 0.536666667 50 46.25 39.06 23.8 45.10333333 0.038768505 0.917606538 "GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm" GO:0000166///nucleotide binding+++GO:0000405///bubble DNA binding+++GO:0003676///nucleic acid binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0009378///four-way junction helicase activity+++GO:0016787///hydrolase activity+++GO:0032357///oxidized purine DNA binding+++GO:0036310///annealing helicase activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0046872///metal ion binding+++GO:0061821///telomeric D-loop binding GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000733///DNA strand renaturation+++GO:0001501///skeletal system development+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0008284///positive regulation of cell proliferation+++GO:0032508///DNA duplex unwinding+++GO:0043473///pigmentation+++GO:0045875///negative regulation of sister chromatid cohesion+++GO:0048705///skeletal system morphogenesis+++GO:0061820///telomeric D-loop disassembly 79459 79459 'Aldoart2' mRNA 4 5 2 0.14 0.17 0.07 0 0 0 0.126666667 0 0 0 0 3.666666667 0 0.05832787 -4.312664742 00010///Glycolysis / Gluconeogenesis+++00030///Pentose phosphate pathway+++00051///Fructose and mannose metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++04066///HIF-1 signaling pathway GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0061827///sperm head+++GO:0070062///extracellular exosome GO:0003824///catalytic activity+++GO:0004332///fructose-bisphosphate aldolase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016829///lyase activity+++GO:0042802///identical protein binding+++GO:0070061///fructose binding "GO:0006000///fructose metabolic process+++GO:0006096///glycolytic process+++GO:0006754///ATP biosynthetic process+++GO:0006941///striated muscle contraction+++GO:0007339///binding of sperm to zona pellucida+++GO:0008360///regulation of cell shape+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0046716///muscle cell cellular homeostasis" 79464 79464 'Lias' mRNA 704 694 709 13.53 13.15 14.46 14.38 12.63 14.57 13.71333333 13.86 862 737 844 702.3333333 814.3333333 0.077018438 0.199625186 00785///Lipoic acid metabolism+++01240///Biosynthesis of cofactors GO:0005739///mitochondrion "GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0016783///sulfurtransferase activity+++GO:0016992///lipoate synthase activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0102552///lipoyl synthase activity (acting on glycine-cleavage complex H protein+++GO:0102553///lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)" GO:0001843///neural tube closure+++GO:0006954///inflammatory response+++GO:0006979///response to oxidative stress+++GO:0009107///lipoate biosynthetic process+++GO:0009249///protein lipoylation+++GO:0032496///response to lipopolysaccharide 79554 79554 'Cptp' mRNA 413 478 450 8.6 9.8 9.94 8.13 9.17 8.36 9.446666667 8.553333333 449 495 447 447 463.6666667 0.822931675 0.041420897 GO:0005634///nucleus+++GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane GO:0005543///phospholipid binding+++GO:0008289///lipid binding+++GO:0120013///intermembrane lipid transfer activity+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0006869///lipid transport+++GO:0010507///negative regulation of autophagy+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0035627///ceramide transport+++GO:0120009///intermembrane lipid transfer+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1902389///ceramide 1-phosphate transport 79555 79555 'BC005537' mRNA 459 490 371 10.01 10.52 8.58 13.1 11.9 13.55 9.703333333 12.85 691 613 692 440 665.3333333 9.46E-07 0.588604843 GO:0003674///molecular_function GO:0008150///biological_process 79560 79560 'Ublcp1' mRNA 1201 1217 1126 31.71 31.7 31.56 25.07 24.81 26.2 31.65666667 25.36 1091 1056 1106 1181.333333 1084.333333 0.139727297 -0.134552391 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity GO:0006470///protein dephosphorylation 79565 79565 'Mettl27' mRNA 858 777 782 17.33 15.33 16.64 8.49 8.88 9.93 16.43333333 9.1 478 493 538 805.6666667 503 3.14E-10 -0.690900335 GO:0008168///methyltransferase activity 79566 79566 'Sh3bp5l' mRNA 1105 1231 1021 20.05 21.98 19.64 18.1 16.73 17.96 20.55666667 17.59666667 1148 1037 1102 1119 1095.666667 0.739272063 -0.040303714 GO:0005737///cytoplasm GO:0004860///protein kinase inhibitor activity+++GO:0005085///guanyl-nucleotide exchange factor activity GO:0035556///intracellular signal transduction+++GO:0061099///negative regulation of protein tyrosine kinase activity 80280 80280 'Cdk5rap3' mRNA 1470 1429 1377 38.38 37.07 37.98 41.97 42.69 40.55 37.81 41.73666667 1832 1838 1721 1425.333333 1797 2.65E-05 0.322904906 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030332///cyclin binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0044877///protein-containing complex binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:0097371///MDM2/MDM4 family protein binding GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001889///liver development+++GO:0001933///negative regulation of protein phosphorylation+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0010921///regulation of phosphatase activity+++GO:0030262///apoptotic nuclear changes+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043407///negative regulation of MAP kinase activity+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0044818///mitotic G2/M transition checkpoint+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060318///definitive erythrocyte differentiation+++GO:0071569///protein ufmylation+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:1903363///negative regulation of cellular protein catabolic process+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process 80281 80281 'Cttnbp2nl' mRNA 904 899 832 10 9.78 9.75 15.41 14.39 14.04 9.843333333 14.61333333 1605 1466 1416 878.3333333 1495.666667 5.19E-20 0.756397481 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0042995///cell projection GO:0051721///protein phosphatase 2A binding GO:0006470///protein dephosphorylation+++GO:0032410///negative regulation of transporter activity+++GO:0034763///negative regulation of transmembrane transport 80283 80283 'Abtb1' mRNA 1046 977 1013 32.32 29.7 33.16 18.95 18.68 18.74 31.72666667 18.79 707 679 674 1012 686.6666667 2.48E-09 -0.572541338 GO:0000151///ubiquitin ligase complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003746///translation elongation factor activity GO:0006412///translation+++GO:0006414///translational elongation 80284 80284 'Smim12' mRNA 849 875 867 52.83 53.84 57.25 51.77 59.35 52 54.64 54.37333333 954 1066 926 863.6666667 982 0.117567892 0.173657982 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 80285 80285 'Parp9' mRNA 693.25 752.08 805.05 12.1 12.98 14.99 23.65 22.87 24.25 13.35666667 23.59 1550.58 1459.77 1540.65 750.1266667 1517 1.14E-25 1.000696096 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0090734///site of DNA damage GO:0003714///transcription corepressor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0004857///enzyme inhibitor activity+++GO:0016740///transferase activity+++GO:0019899///enzyme binding+++GO:0042393///histone binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0072570///ADP-D-ribose binding+++GO:0097677///STAT family protein binding+++GO:1990404///protein ADP-ribosylase activity "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006471///protein ADP-ribosylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0035563///positive regulation of chromatin binding+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043086///negative regulation of catalytic activity+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051607///defense response to virus+++GO:0060330///regulation of response to interferon-gamma+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0070212///protein poly-ADP-ribosylation+++GO:1900182///positive regulation of protein localization to nucleus+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining" 80286 80286 'Tusc3' mRNA 3021 3088 2902 112.29 113.75 114.2 78.02 73.55 75.3 113.4133333 75.62333333 2360 2190 2188 3003.666667 2246 9.15E-12 -0.431282393 00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015095///magnesium ion transmembrane transporter activity+++GO:0062062///oligosaccharyltransferase complex binding GO:0006486///protein glycosylation+++GO:0015693///magnesium ion transport+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0050890///cognition+++GO:1903830///magnesium ion transmembrane transport 80287 80287 'Apobec3' mRNA 1683.43 1667.88 1613.83 30.96 30.98 31.98 44.83 43.56 43.69 31.30666667 44.02666667 2626.75 2448.8 2482.48 1655.046667 2519.343333 8.89E-19 0.594231907 05170///Human immunodeficiency virus 1 infection GO:0000932///P-body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0004126///cytidine deaminase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0047844///deoxycytidine deaminase activity GO:0002244///hematopoietic progenitor cell differentiation+++GO:0002376///immune system process+++GO:0009972///cytidine deamination+++GO:0010529///negative regulation of transposition+++GO:0016554///cytidine to uridine editing+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0050688///regulation of defense response to virus+++GO:0051607///defense response to virus+++GO:0070383///DNA cytosine deamination+++GO:0080111///DNA demethylation+++GO:1903900///regulation of viral life cycle 80288 80288 'Bcl9l' mRNA 912 871 692 7.23 6.82 5.73 6.34 6.57 6.39 6.593333333 6.433333333 929 937 908 825 924.6666667 0.16865572 0.157506583 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:1990907///beta-catenin-TCF complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding "GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0022604///regulation of cell morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035914///skeletal muscle cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060070///canonical Wnt signaling pathway" 80289 80289 'Lysmd3' mRNA 452 397 423 6.96 5.94 6.76 7.22 6.26 7.22 6.553333333 6.9 546 458 546 424 516.6666667 0.049870422 0.271350986 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0007030///Golgi organization 80290 80290 'Gpr146' mRNA 1501 1580 1488 19.52 20.35 20.61 24.01 21.16 21.98 20.16 22.38333333 2125 1834 1897 1523 1952 9.61E-06 0.345200138 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process 80291 80291 'Rilpl2' mRNA 637 621 587 30.76 29.61 30.08 35.25 33.6 35.89 30.15 34.91333333 838 779 825 615 814 8.82E-05 0.393020098 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity GO:0003382///epithelial cell morphogenesis+++GO:0015031///protein transport+++GO:0060271///cilium assembly+++GO:1903445///protein transport from ciliary membrane to plasma membrane 80292 80292 'Zxdc' mRNA 163 173 171 2.06 2.09 2.24 2.12 1.53 1.86 2.13 1.836666667 200 136 172 169 169.3333333 0.966748777 -0.01261815 GO:0005575///cellular_component+++GO:0005634///nucleus GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0030275///LRR domain binding+++GO:0046872///metal ion binding+++GO:0070742///C2H2 zinc finger domain binding "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated" 80294 80294 'Pofut2' mRNA 1755 1690 1757 44.55 42.25 47.31 43.18 43.45 41.75 44.70333333 42.79333333 1956 1922 1831 1734 1903 0.164367817 0.120898949 00514///Other types of O-glycan biosynthesis GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus "GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046922///peptide-O-fucosyltransferase activity" GO:0001707///mesoderm formation+++GO:0005975///carbohydrate metabolic process+++GO:0006004///fucose metabolic process+++GO:0006486///protein glycosylation+++GO:0010468///regulation of gene expression+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0036065///fucosylation+++GO:0036066///protein O-linked fucosylation+++GO:0051046///regulation of secretion+++GO:1903334///positive regulation of protein folding 80297 80297 'Sptbn4' mRNA 16 18 10 0.15 0.12 0.11 0.13 0.08 0.12 0.126666667 0.11 13 9 12 14.66666667 11.33333333 0.669862772 -0.376386451 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0005912///adherens junction+++GO:0008091///spectrin+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0016605///PML body+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030864///cortical actin cytoskeleton+++GO:0033268///node of Ranvier+++GO:0033270///paranode region of axon+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043194///axon initial segment+++GO:0043203///axon hillock+++GO:0070852///cell body fiber GO:0003779///actin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019902///phosphatase binding+++GO:0030506///ankyrin binding+++GO:0030507///spectrin binding+++GO:0051015///actin filament binding GO:0002028///regulation of sodium ion transport+++GO:0007010///cytoskeleton organization+++GO:0007409///axonogenesis+++GO:0007605///sensory perception of sound+++GO:0007628///adult walking behavior+++GO:0008104///protein localization+++GO:0009566///fertilization+++GO:0010459///negative regulation of heart rate+++GO:0019226///transmission of nerve impulse+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0022414///reproductive process+++GO:0030036///actin cytoskeleton organization+++GO:0030534///adult behavior+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0034613///cellular protein localization+++GO:0040018///positive regulation of multicellular organism growth+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0051693///actin filament capping+++GO:0061337///cardiac conduction+++GO:0072659///protein localization to plasma membrane 80334 80334 'Kcnip4' mRNA 1390.15 1305.24 1116.37 4.8 4.49 4.19 1.86 1.67 1.98 4.493333333 1.836666667 555.34 440.95 556.11 1270.586667 517.4666667 1.56E-34 -1.306817383 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0005509///calcium ion binding+++GO:0015459///potassium channel regulator activity+++GO:0046872///metal ion binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport 80384 80384 'Tex21' mRNA 2 0 0 0.06 0 0 0.03 0 0.03 0.02 0.02 1 0 1 0.666666667 0.666666667 0.999865452 5.07E-04 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 80385 80385 'Tusc2' mRNA 1480 1578 899 51.89 54.54 33.44 21.72 33.33 30.62 46.62333333 28.55666667 712 1066 971 1319 916.3333333 0.105807691 -0.520872021 GO:0005739///mitochondrion GO:0003674///molecular_function GO:0001779///natural killer cell differentiation+++GO:0006909///phagocytosis+++GO:0006954///inflammatory response+++GO:0032618///interleukin-15 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0048469///cell maturation+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070945///neutrophil mediated killing of gram-negative bacterium+++GO:0071609///chemokine (C-C motif) ligand 5 production+++GO:2000377///regulation of reactive oxygen species metabolic process 80509 80509 'Med8' mRNA 457 488 544 19.3 20.5 23.91 29.2 29.76 30.61 21.23666667 29.85666667 746 760 762 496.3333333 756 8.75E-07 0.592052578 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex+++GO:0070847///core mediator complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination 80517 80517 'Herpud2' mRNA 684.94 562.01 317.58 12.34 10.51 5.8 6.01 8.18 8.18 9.55 7.456666667 400.96 502.67 503.38 521.51 469.0033333 0.740165623 -0.149088667 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006986///response to unfolded protein+++GO:0007283///spermatogenesis+++GO:0030968///endoplasmic reticulum unfolded protein response 80707 80707 'Wwox' mRNA 1011.96 1060.13 1038.03 23.61 22.21 22.99 6.16 5.92 5.78 22.93666667 5.953333333 341.93 333.33 349.08 1036.706667 341.4466667 8.20E-55 -1.616152538 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005902///microvillus+++GO:0090575///RNA polymerase II transcription factor complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding GO:0001649///osteoblast differentiation+++GO:0006915///apoptotic process+++GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048705///skeletal system morphogenesis+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 80708 80708 'Pacsin3' mRNA 1785 1849 1704 54.57 55.75 55.15 41.72 45.58 43.76 55.15666667 43.68666667 1574 1687 1593 1779.333333 1618 0.075135103 -0.147399859 GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008092///cytoskeletal protein binding+++GO:0008289///lipid binding+++GO:0019855///calcium channel inhibitor activity+++GO:0042802///identical protein binding GO:0006897///endocytosis+++GO:0007010///cytoskeleton organization+++GO:0030100///regulation of endocytosis+++GO:0045806///negative regulation of endocytosis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0051926///negative regulation of calcium ion transport+++GO:0097320///plasma membrane tubulation 80718 80718 'Rab27b' mRNA 696 726 607.93 5.21 5.34 4.8 2.38 2.31 2.3 5.116666667 2.33 367.01 350.98 348 676.6433333 355.33 1.14E-16 -0.939146504 04972///Pancreatic secretion GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030141///secretory granule+++GO:0030667///secretory granule membrane+++GO:0032585///multivesicular body membrane+++GO:0042470///melanosome+++GO:0042589///zymogen granule membrane+++GO:0098993///anchored component of synaptic vesicle membrane+++GO:1904115///axon cytoplasm GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0019003///GDP binding+++GO:0019904///protein domain specific binding+++GO:0031489///myosin V binding GO:0017157///regulation of exocytosis+++GO:0032402///melanosome transport+++GO:0045921///positive regulation of exocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0071985///multivesicular body sorting pathway+++GO:0099641///anterograde axonal protein transport 80719 80719 'Igsf6' mRNA 68 62 68 1.8 1.62 1.91 15.49 15.18 13.91 1.776666667 14.86 672 643 584 66 633 9.68E-89 3.249015877 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 80720 80720 'Pbx4' mRNA 54 72 79 2.71 3.7 4.43 1.08 0.92 1.7 3.613333333 1.233333333 24 21 35 68.33333333 26.66666667 4.74E-04 -1.374471264 GO:0001741///XY body+++GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding" "GO:0001654///eye development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0009887///animal organ morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048568///embryonic organ development+++GO:0048666///neuron development" 80721 80721 'Slc19a3' mRNA 63 68 75 1.14 1.23 1.45 0.87 0.79 1.08 1.273333333 0.913333333 53 48 65 68.66666667 55.33333333 0.382095051 -0.326613855 04977///Vitamin digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008517///folic acid transmembrane transporter activity+++GO:0015234///thiamine transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity GO:0015884///folic acid transport+++GO:0015888///thiamine transport+++GO:0051180///vitamin transport+++GO:0055085///transmembrane transport+++GO:0071934///thiamine transmembrane transport 80732 80732 'Mynn' mRNA 774 851 791 7.5 8.1 8.14 5.36 5.69 5.64 7.913333333 5.563333333 636 662 647 805.3333333 648.3333333 0.002017435 -0.324013435 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor 80733 80733 'Car15' mRNA 54 72 60 3.05 4.02 3.6 1.77 1.26 1.07 3.556666667 1.366666667 36 25 21 62 27.33333333 0.002479816 -1.19537741 00910///Nitrogen metabolism GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0046658///anchored component of plasma membrane GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0016836///hydro-lyase activity+++GO:0046872///metal ion binding GO:0006730///one-carbon metabolic process 80743 80743 'Vps16' mRNA 1140.46 1224.66 1382.2 22.64 23.74 28.92 23.61 24.76 23.8 25.1 24.05666667 1370.89 1408.04 1337.12 1249.106667 1372.016667 0.323118565 0.119581308 05132///Salmonella infection GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0005776///autophagosome+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0030123///AP-3 adaptor complex+++GO:0030136///clathrin-coated vesicle+++GO:0030424///axon+++GO:0030897///HOPS complex+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0033263///CORVET complex+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding "GO:0006886///intracellular protein transport+++GO:0006914///autophagy+++GO:0007033///vacuole organization+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0042144///vacuole fusion, non-autophagic+++GO:0046718///viral entry into host cell+++GO:0097352///autophagosome maturation" 80744 80744 'Cwc22' mRNA 1294.88 1311.83 1262.54 18.28 18.74 19.54 20.99 18.69 20.38 18.85333333 20.02 1598.37 1414.95 1505.43 1289.75 1506.25 0.011115721 0.211509812 GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003723///RNA binding "GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing" 80748 80748 'BC004004' mRNA 1721 1773 1682 34.17 34.58 35.25 40.64 41.03 40 34.66666667 40.55666667 2360 2326 2250 1725.333333 2312 2.61E-09 0.41065131 GO:0000139///Golgi membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030496///midbody GO:0003674///molecular_function GO:0042060///wound healing+++GO:0045787///positive regulation of cell cycle+++GO:0050673///epithelial cell proliferation+++GO:1901727///positive regulation of histone deacetylase activity 80749 80749 'Lrfn1' mRNA 29 27 8 0.51 0.43 0.13 0.29 0.09 0.19 0.356666667 0.19 18 6 12 21.33333333 12 0.291850933 -0.828923524 GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098839///postsynaptic density membrane+++GO:0099061///integral component of postsynaptic density membrane GO:0005515///protein binding GO:0099151///regulation of postsynaptic density assembly 80750 80750 'N4bp1' mRNA 824.53 839.28 821.62 5.75 5.72 5.73 7.39 6.2 7.03 5.733333333 6.873333333 1203.01 1011.25 1084.98 828.4766667 1099.746667 3.48E-05 0.395418866 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0004518///nuclease activity+++GO:0004540///ribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043130///ubiquitin binding GO:0001818///negative regulation of cytokine production+++GO:0002376///immune system process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034644///cellular response to UV+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 80751 80751 'Rnf34' mRNA 1085 1110 1032 31.77 31.95 32.01 28.69 28.95 30.82 31.91 29.48666667 1126 1108 1170 1075.666667 1134.666667 0.529000685 0.066092201 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0016607///nuclear speck GO:0002039///p53 binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1901981///phosphatidylinositol phosphate binding "GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0016567///protein ubiquitination+++GO:0035872///nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070417///cellular response to cold+++GO:0070936///protein K48-linked ubiquitination+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000374///regulation of oxygen metabolic process+++GO:2001271///negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis" 80752 80752 'Fam20c' mRNA 1264 1341 1368 23.14 24.14 26.54 51.97 57.21 51.92 24.60666667 53.7 3268 3515 3161 1324.333333 3314.666667 1.49E-60 1.310843948 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus "GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding" GO:0001501///skeletal system development+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0030501///positive regulation of bone mineralization+++GO:0031214///biomineral tissue development+++GO:0036179///osteoclast maturation+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0046034///ATP metabolic process+++GO:0051174///regulation of phosphorus metabolic process+++GO:0070166///enamel mineralization+++GO:0071895///odontoblast differentiation+++GO:0097187///dentinogenesis 80782 80782 'Klrb1b' mRNA 12 18.34 9 0.31 0.49 0.24 0.29 0.45 0.33 0.346666667 0.356666667 13 19.28 14.06 13.11333333 15.44666667 0.790763472 0.239117346 05144///Malaria GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding GO:0045953///negative regulation of natural killer cell mediated cytotoxicity 80794 80794 'Cblc' mRNA 266 305 292 9.32 10.54 10.85 8.05 8.06 6.24 10.23666667 7.45 264 258 198 287.6666667 240 0.144935622 -0.274534074 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis GO:0000151///ubiquitin ligase complex+++GO:0005886///plasma membrane+++GO:0045121///membrane raft GO:0001784///phosphotyrosine residue binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding+++GO:0047690///aspartyltransferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007175///negative regulation of epidermal growth factor-activated receptor activity+++GO:0016567///protein ubiquitination+++GO:0023051///regulation of signaling+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0043407///negative regulation of MAP kinase activity 80795 80795 'Selenok' mRNA 4788 5067 4965 299.4 313.3 329.43 302.95 319.36 299.3 314.0433333 307.2033333 5555 5708 5304 4940 5522.333333 0.032032847 0.148339827 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0042802///identical protein binding GO:0002230///positive regulation of defense response to virus by host+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006979///response to oxidative stress+++GO:0010742///macrophage derived foam cell differentiation+++GO:0018345///protein palmitoylation+++GO:0030335///positive regulation of cell migration+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0032722///positive regulation of chemokine production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042102///positive regulation of T cell proliferation+++GO:0045728///respiratory burst after phagocytosis+++GO:0050848///regulation of calcium-mediated signaling+++GO:0051223///regulation of protein transport+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:2000406///positive regulation of T cell migration+++GO:2001256///regulation of store-operated calcium entry 80797 80797 'Clca3a2' mRNA 43.15 42 48.56 0.8 0.69 0.77 56.42 56.74 53.83 0.753333333 55.66333333 4061.59 4055.94 3746.75 44.57 3954.76 0 6.467437131 04924///Renin secretion+++04972///Pancreatic secretion GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009925///basal plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0031965///nuclear membrane GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005254///chloride channel activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0015276///ligand-gated ion channel activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007155///cell adhesion+++GO:0015698///inorganic anion transport+++GO:0034220///ion transmembrane transport+++GO:0043276///anoikis+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand 80837 80837 'Rhoj' mRNA 879 988 944 20.88 23.11 23.78 28.04 28.64 26.41 22.59 27.69666667 1358 1354 1238 937 1316.666667 2.23E-07 0.478325137 05132///Salmonella infection GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0005525///GTP binding GO:0001525///angiogenesis+++GO:0006897///endocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0010594///regulation of endothelial cell migration+++GO:0016477///cell migration+++GO:0030031///cell projection assembly+++GO:0030036///actin cytoskeleton organization+++GO:0032488///Cdc42 protein signal transduction+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:1903670///regulation of sprouting angiogenesis 80838 80838 'H1f1' mRNA 1 1 2 0.09 0.09 0.2 0.41 0.08 0.93 0.126666667 0.473333333 5 1 11 1.333333333 5.666666667 0.206853042 2.061543088 GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0000791///euchromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0009986///cell surface+++GO:0031982///vesicle GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0031490///chromatin DNA binding+++GO:0031492///nucleosomal DNA binding GO:0006334///nucleosome assembly+++GO:0007283///spermatogenesis+++GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0031936///negative regulation of chromatin silencing+++GO:0045910///negative regulation of DNA recombination+++GO:0048260///positive regulation of receptor-mediated endocytosis 80857 80857 'Fgf20' mRNA 5 9 14 0.2 0.36 0.6 0.1 0.14 0.18 0.386666667 0.14 3 4 5 9.333333333 4 0.258413973 -1.24762409 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity+++GO:0090722///receptor-receptor interaction GO:0001934///positive regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045664///regulation of neuron differentiation+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060113///inner ear receptor cell differentiation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade 80859 80859 'Nfkbiz' mRNA 562 490 528 8.41 7.23 8.41 7.02 6.17 6.81 8.016666667 6.666666667 538 462 505 526.6666667 501.6666667 0.59149044 -0.08418341 05202///Transcriptional misregulation in cancer GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0005515///protein binding GO:0006954///inflammatory response+++GO:0010468///regulation of gene expression+++GO:0050729///positive regulation of inflammatory response+++GO:0050852///T cell receptor signaling pathway+++GO:2000321///positive regulation of T-helper 17 cell differentiation 80860 80860 'Ghdc' mRNA 711.04 635.01 647.07 18.64 16.3 18.06 17.44 18.89 16.82 17.66666667 17.71666667 766.42 807.65 718.15 664.3733333 764.0733333 0.107712764 0.189521123 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum GO:0016881///acid-amino acid ligase activity 80861 80861 'Dhx58' mRNA 549 545 480 12.74 12.43 11.8 26.45 25.5 26.71 12.32333333 26.22 1312 1234 1281 524.6666667 1275.666667 7.04E-46 1.271611662 04622///RIG-I-like receptor signaling pathway GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0003725///double-stranded RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0002376///immune system process+++GO:0009615///response to virus+++GO:0009617///response to bacterium+++GO:0032480///negative regulation of type I interferon production+++GO:0032481///positive regulation of type I interferon production+++GO:0032728///positive regulation of interferon-beta production+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045824///negative regulation of innate immune response+++GO:0051607///defense response to virus+++GO:1900245///positive regulation of MDA-5 signaling pathway+++GO:1900246///positive regulation of RIG-I signaling pathway 80876 80876 'Ifitm2' mRNA 3580 3218 3371 411.1 368.52 408.87 1498.38 1658.75 1515.04 396.1633333 1557.39 14818 15978 14490 3389.666667 15095.33333 1.56E-222 2.14287415 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0032991///protein-containing complex GO:0003674///molecular_function GO:0002376///immune system process+++GO:0007507///heart development+++GO:0009615///response to virus+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0035458///cellular response to interferon-beta+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway 80877 80877 'Lrba' mRNA 1047 1160 1061 5.82 6.57 6.23 2.62 2.2 2.48 6.206666667 2.433333333 528 436 458 1089.333333 474 9.86E-33 -1.213278383 GO:0005764///lysosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle GO:0019901///protein kinase binding+++GO:0051018///protein kinase A binding GO:0007165///signal transduction+++GO:0008104///protein localization+++GO:0016197///endosomal transport+++GO:1990830///cellular response to leukemia inhibitory factor 80879 80879 'Slc16a3' mRNA 172.93 188 177 4.05 4.36 4.41 14.49 13.78 12.77 4.273333333 13.68 708 643 600 179.31 650.3333333 3.01E-44 1.84873907 05230///Central carbon metabolism in cancer GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0031965///nuclear membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099061///integral component of postsynaptic density membrane GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0022857///transmembrane transporter activity GO:0015718///monocarboxylic acid transport+++GO:0035873///lactate transmembrane transport+++GO:0035879///plasma membrane lactate transport+++GO:0055085///transmembrane transport 80880 80880 'Kank3' mRNA 515 509 567 14.65 11.67 19.21 14.94 16.83 15.49 15.17666667 15.75333333 602 586 547 530.3333333 578.3333333 0.455061299 0.109981236 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0003674///molecular_function GO:0030837///negative regulation of actin filament polymerization+++GO:0051497///negative regulation of stress fiber assembly 80883 80883 'Ntng1' mRNA 129 131 99 0.95 0.82 0.69 0.51 0.27 0.25 0.82 0.343333333 63 44 47 119.6666667 51.33333333 1.13E-05 -1.230347116 04360///Axon guidance+++04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0043256///laminin complex+++GO:0046658///anchored component of plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0099029///anchored component of presynaptic active zone membrane GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0098632///cell-cell adhesion mediator activity GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007409///axonogenesis+++GO:0009887///animal organ morphogenesis+++GO:0009888///tissue development+++GO:0010975///regulation of neuron projection development+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0050804///modulation of chemical synaptic transmission+++GO:0070831///basement membrane assembly+++GO:0099560///synaptic membrane adhesion+++GO:0150011///regulation of neuron projection arborization+++GO:2001222///regulation of neuron migration 80884 80884 'Maged2' mRNA 1996 2057 2033 52.94 53.7 57.33 46.52 47.92 46.05 54.65666667 46.83 2034 2036 1943 2028.666667 2004.333333 0.766072977 -0.029905924 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol GO:0003674///molecular_function GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007565///female pregnancy+++GO:0070294///renal sodium ion absorption 80885 80885 'Hcar2' mRNA 40 35 40 1.17 1.01 1.24 2.3 1.86 1.79 1.14 1.983333333 90 71 68 38.33333333 76.33333333 0.004043524 0.977878326 04024///cAMP signaling pathway GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction GO:0001614///purinergic nucleotide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005525///GTP binding+++GO:0070553///nicotinic acid receptor activity GO:0001781///neutrophil apoptotic process+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0050995///negative regulation of lipid catabolic process+++GO:0070165///positive regulation of adiponectin secretion 80886 80886 'Senp3' mRNA 2114 2045 1977 52.45 49.62 52.6 40.08 37.54 41.36 51.55666667 39.66 1849 1687 1854 2045.333333 1796.666667 0.008712751 -0.199044709 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0071339///MLL1 complex GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016929///SUMO-specific protease activity+++GO:0070140///SUMO-specific isopeptidase activity GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0019538///protein metabolic process 80888 80888 'Hspb8' mRNA 1898 1932 1966 60.17 60.36 66.12 103.38 111.23 104.72 62.21666667 106.4433333 3748 3936 3674 1932 3786 1.95E-41 0.957990943 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0101031///chaperone complex GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity GO:0034620///cellular response to unfolded protein+++GO:1905337///positive regulation of aggrephagy 80889 80889 'Tlnrd1' mRNA 215 215.62 29.38 3.02 2.98 0.44 1.2 1.57 2.28 2.146666667 1.683333333 98 125.82 180.88 153.3333333 134.9 0.879031168 -0.163971885 GO:0001725///stress fiber GO:0003779///actin binding+++GO:0042802///identical protein binding GO:0008150///biological_process 80890 80890 'Trim2' mRNA 2987 3051 3117 20.33 20.69 23.02 15.78 15.28 15.73 21.34666667 15.59666667 2639 2485 2544 3051.666667 2556 1.58E-04 -0.269489356 GO:0005737///cytoplasm GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0017022///myosin binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043523///regulation of neuron apoptotic process+++GO:1990830///cellular response to leukemia inhibitory factor 80891 80891 'Fcrls' mRNA 365 344 337 10.07 9.33 9.92 88.57 87.98 91.03 9.773333333 89.19333333 3664 3557 3641 348.6666667 3620.666667 0 3.365100736 GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005044///scavenger receptor activity+++GO:0019903///protein phosphatase binding+++GO:0035591///signaling adaptor activity GO:0006897///endocytosis+++GO:0007166///cell surface receptor signaling pathway 80892 80892 'Zfhx4' mRNA 2009 2056 1878 7.47 7.52 7.38 7.59 6.26 6.77 7.456666667 6.873333333 2354 1893 2034 1981 2093.666667 0.496274272 0.06720089 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 80893 80893 'Tmprss5' mRNA 739 914 777 20.41 24.9 22.72 7.21 7.14 6.4 22.67666667 6.916666667 300 291 257 810 282.6666667 2.59E-35 -1.529681845 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0004252///serine-type endopeptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:0006897///endocytosis 80898 80898 'Erap1' mRNA 1023.81 1074.26 934.22 14.39 15.75 13.62 20.84 20.87 22.72 14.58666667 21.47666667 1716.06 1598.88 1708.37 1010.763333 1674.436667 1.74E-20 0.718224808 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004175///endopeptidase activity+++GO:0004177///aminopeptidase activity+++GO:0005138///interleukin-6 receptor binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0008233///peptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0043171///peptide catabolic process+++GO:0045766///positive regulation of angiogenesis 80901 80901 'Cxcr6' mRNA 47 57 50 1.42 1.7 1.61 2.61 2.18 2.04 1.576666667 2.276666667 99 81 75 51.33333333 85 0.023900408 0.714676464 04060///Cytokine-cytokine receptor interaction+++04062///Chemokine signaling pathway GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0004950///chemokine receptor activity+++GO:0015026///coreceptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0016494///C-X-C chemokine receptor activity+++GO:0019957///C-C chemokine binding+++GO:0019958///C-X-C chemokine binding GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019722///calcium-mediated signaling+++GO:0060326///cell chemotaxis+++GO:0070098///chemokine-mediated signaling pathway 80902 80902 'Zfp202' mRNA 425.1 444.58 407.07 4.04 4.13 4.11 3.03 3.14 2.58 4.093333333 2.916666667 348.38 332.62 290.02 425.5833333 323.6733333 0.003483535 -0.407035731 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016604///nuclear body "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 80903 80903 'Fgf16' mRNA 8 1 0 0.14 0.02 0 0.08 0.03 0.1 0.053333333 0.07 5 2 6 3 4.333333333 0.785645999 0.538352548 04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04020///Calcium signaling pathway+++04151///PI3K-Akt signaling pathway+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++05207///Chemical carcinogenesis - receptor activation+++05218///Melanoma+++05224///Breast cancer+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005104///fibroblast growth factor receptor binding+++GO:0008083///growth factor activity GO:0001934///positive regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0030334///regulation of cell migration+++GO:0070349///positive regulation of brown fat cell proliferation+++GO:2000546///positive regulation of endothelial cell chemotaxis to fibroblast growth factor 80904 80904 'Dtx3' mRNA 5858 5999 4176 152.14 153.16 114.82 65.59 64.8 62.69 140.04 64.36 2844 2769 2641 5344.333333 2751.333333 4.30E-27 -0.962147885 04330///Notch signaling pathway GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination 80905 80905 'Polh' mRNA 131.04 111.63 117 2.22 1.91 2.13 2.59 2.53 2.49 2.086666667 2.536666667 174 168 164 119.89 168.6666667 0.026476119 0.48289453 01524///Platinum drug resistance+++03460///Fanconi anemia pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005657///replication fork+++GO:0005829///cytosol+++GO:0035861///site of double-strand break GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding GO:0000731///DNA synthesis involved in DNA repair+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006290///pyrimidine dimer repair+++GO:0006301///postreplication repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009314///response to radiation+++GO:0010225///response to UV-C+++GO:0042276///error-prone translesion synthesis+++GO:0071494///cellular response to UV-C+++GO:0071897///DNA biosynthetic process 80906 80906 'Kcnip2' mRNA 11 14 13 0.28 0.39 0.39 0.1 0.23 0.13 0.353333333 0.153333333 4 9 5 12.66666667 6 0.234684507 -1.08545535 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane GO:0005244///voltage-gated ion channel activity+++GO:0005250///A-type (transient outward) potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005509///calcium ion binding+++GO:0015459///potassium channel regulator activity+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0071805///potassium ion transmembrane transport+++GO:0086009///membrane repolarization+++GO:0097623///potassium ion export across plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:1903766///positive regulation of potassium ion export across plasma membrane 80907 80907 'Lactb' mRNA 48 68 28 1.34 1.87 0.83 1.63 2.27 2.44 1.346666667 2.113333333 67 91 97 48 85 0.024930418 0.829129645 GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding GO:0006508///proteolysis+++GO:0006629///lipid metabolic process+++GO:0019216///regulation of lipid metabolic process 80908 80908 'Abo' mRNA 1 0 0 0.04 0 0 0.03 0 0 0.013333333 0.01 1 0 0 0.333333333 0.333333333 0.998591786 -0.011756601 00601///Glycosphingolipid biosynthesis - lacto and neolacto series GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0032580///Golgi cisterna membrane "GO:0000166///nucleotide binding+++GO:0001962///alpha-1,3-galactosyltransferase activity+++GO:0003823///antigen binding+++GO:0004380///glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity+++GO:0004381///fucosylgalactoside 3-alpha-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding" GO:0005975///carbohydrate metabolic process+++GO:0006486///protein glycosylation+++GO:0030259///lipid glycosylation 80909 80909 'Castor2' mRNA 655 798 348 7.35 8.81 4.14 3.21 3.59 3.21 6.766666667 3.336666667 329 360 319 600.3333333 336 0.016554469 -0.831465724 04150///mTOR signaling pathway GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0061700///GATOR2 complex GO:0042802///identical protein binding GO:1902531///regulation of intracellular signal transduction+++GO:1903577///cellular response to L-arginine+++GO:1904262///negative regulation of TORC1 signaling 80910 80910 'Gpr84' mRNA 6 2 9 0.23 0.07 0.36 5.4 6.12 5.64 0.22 5.72 165 182 166 5.666666667 171 9.36E-30 4.900490277 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0001604///urotensin II receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway 80911 80911 'Acox3' mRNA 869 755 758 9.94 8.36 9.56 11.51 11.17 11.71 9.286666667 11.46333333 1042 991 1046 794 1026.333333 2.61E-04 0.358701225 00071///Fatty acid degradation+++00410///beta-Alanine metabolism+++00592///alpha-Linolenic acid metabolism+++00640///Propanoate metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04024///cAMP signaling pathway+++04146///Peroxisome+++04936///Alcoholic liver disease GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix "GO:0003997///acyl-CoA oxidase activity+++GO:0005504///fatty acid binding+++GO:0016402///pristanoyl-CoA oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0055088///lipid homeostasis 80912 80912 'Pum1' mRNA 2743 2763 2516 28.28 27.67 27.19 21.14 19.03 20.79 27.71333333 20.32 2374 2104 2271 2674 2249.666667 1.15E-04 -0.260623507 05017///Spinocerebellar ataxia GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0035198///miRNA binding GO:0006417///regulation of translation+++GO:0007283///spermatogenesis+++GO:0008344///adult locomotory behavior+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0016441///posttranscriptional gene silencing+++GO:0030154///cell differentiation+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0043488///regulation of mRNA stability+++GO:0048863///stem cell differentiation+++GO:0051726///regulation of cell cycle+++GO:0051983///regulation of chromosome segregation+++GO:0061157///mRNA destabilization+++GO:1900246///positive regulation of RIG-I signaling pathway+++GO:2000637///positive regulation of gene silencing by miRNA 80913 80913 'Pum2' mRNA 1825.01 1852.81 1661 15.38 15.5 14.99 14.17 13.24 13.45 15.29 13.62 1936 1781 1795 1779.606667 1837.333333 0.713442089 0.035423798 05017///Spinocerebellar ataxia GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0035198///miRNA binding GO:0006417///regulation of translation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0034063///stress granule assembly+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0043488///regulation of mRNA stability+++GO:0051983///regulation of chromosome segregation+++GO:1900246///positive regulation of RIG-I signaling pathway+++GO:2000637///positive regulation of gene silencing by miRNA 80914 80914 'Uck2' mRNA 235 271 206 5.8 5.54 4.88 10.65 12.49 11.52 5.406666667 11.55333333 466 551 522 237.3333333 513 1.41E-14 1.105728931 00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004849///uridine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0019206///nucleoside kinase activity+++GO:0042802///identical protein binding GO:0016310///phosphorylation+++GO:0044206///UMP salvage+++GO:0044211///CTP salvage 80915 80915 'Dusp12' mRNA 322 323 314 14.03 13.82 14.54 14.79 16.55 16.63 14.13 15.99 391 424 425 319.6666667 413.3333333 0.010736527 0.3598335 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0019900///kinase binding+++GO:0046872///metal ion binding GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0033133///positive regulation of glucokinase activity+++GO:0035335///peptidyl-tyrosine dephosphorylation 80976 80976 'Syt13' mRNA 1168 1197 1098 16.87 17 16.82 2.37 2.44 2.46 16.89666667 2.423333333 189 190 190 1154.333333 189.6666667 2.76E-127 -2.616279685 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0030424///axon+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0070382///exocytic vesicle GO:0000149///SNARE binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0030276///clathrin binding GO:0006906///vesicle fusion+++GO:0014059///regulation of dopamine secretion+++GO:0016192///vesicle-mediated transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0071277///cellular response to calcium ion 80978 80978 'Mrgprh' mRNA 1 1 0 0.03 0.03 0 0 0 0 0.02 0 0 0 0 0.666666667 0 0.75009672 -1.834425537 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001595///angiotensin receptor activity+++GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0038166///angiotensin-activated signaling pathway 80979 80979 'Slc26a5' mRNA 7 7 15 0.09 0.08 0.2 0.07 0.01 0.01 0.123333333 0.03 7 1 1 9.666666667 3 0.150256665 -1.733885419 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity+++GO:0030507///spectrin binding+++GO:0042802///identical protein binding GO:0002931///response to ischemia+++GO:0007605///sensory perception of sound+++GO:0008272///sulfate transport+++GO:0008360///regulation of cell shape+++GO:0009751///response to salicylic acid+++GO:0010996///response to auditory stimulus+++GO:0015701///bicarbonate transport+++GO:0015755///fructose transmembrane transport+++GO:0019532///oxalate transport+++GO:0034220///ion transmembrane transport+++GO:0034766///negative regulation of ion transmembrane transport+++GO:0035864///response to potassium ion+++GO:0042391///regulation of membrane potential+++GO:0042493///response to drug+++GO:0045793///positive regulation of cell size+++GO:0055085///transmembrane transport+++GO:0090102///cochlea development+++GO:0097066///response to thyroid hormone+++GO:0098656///anion transmembrane transport+++GO:1902074///response to salt+++GO:1902358///sulfate transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:2000147///positive regulation of cell motility 80981 80981 'Arl4d' mRNA 170 170 160 7.36 7.27 7.35 20.6 16.94 17.16 7.326666667 18.23333333 546 438 440 166.6666667 474.6666667 1.29E-23 1.496870544 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport 80982 80982 'Cemip' mRNA 892 908 829 5.54 5.55 5.42 5.1 5.04 5.02 5.503333333 5.053333333 936 908 895 876.3333333 913 0.686091078 0.048335531 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0045334///clathrin-coated endocytic vesicle "GO:0004415///hyalurononglucosaminidase activity+++GO:0005540///hyaluronic acid binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0032050///clathrin heavy chain binding+++GO:0046923///ER retention sequence binding" GO:0007605///sensory perception of sound+++GO:0008152///metabolic process+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0030214///hyaluronan catabolic process+++GO:0030335///positive regulation of cell migration+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0090314///positive regulation of protein targeting to membrane+++GO:1900020///positive regulation of protein kinase C activity 80985 80985 'Trim44' mRNA 1151 1135 1060 10.91 10.58 10.66 9.46 8.19 8.95 10.71666667 8.866666667 1149 972 1053 1115.333333 1058 0.40291942 -0.088276054 GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0002230///positive regulation of defense response to virus by host+++GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050821///protein stabilization+++GO:0061944///negative regulation of protein K48-linked ubiquitination+++GO:1901224///positive regulation of NIK/NF-kappaB signaling" 80986 80986 'Ckap2' mRNA 1 2 7 0.02 0.04 0.15 5.53 4.55 5.87 0.07 5.316666667 300 242 308 3.333333333 283.3333333 8.30E-37 6.393703891 GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton GO:0003674///molecular_function GO:0000281///mitotic cytokinesis+++GO:0006915///apoptotic process+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II 80987 80987 'Nckipsd' mRNA 700 620 644 13.29 11.6 12.78 12.01 11.4 12.83 12.55666667 12.08 714 659 739 654.6666667 704 0.489265914 0.092188224 GO:0005634///nucleus+++GO:0008180///COP9 signalosome GO:0017022///myosin binding+++GO:0017124///SH3 domain binding+++GO:0071933///Arp2/3 complex binding GO:0006897///endocytosis+++GO:0010976///positive regulation of neuron projection development 81000 81000 'Rad54l2' mRNA 280 209 272 1.57 1.15 1.62 1.1 1.07 1.38 1.446666667 1.183333333 226 214 273 253.6666667 237.6666667 0.655707392 -0.109594951 GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003678///DNA helicase activity+++GO:0003712///transcription coregulator activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0070615///nucleosome-dependent ATPase activity GO:0032508///DNA duplex unwinding+++GO:0045944///positive regulation of transcription by RNA polymerase II 81003 81003 'Trim23' mRNA 711 716 743 10.05 9.96 11.15 7.21 6.17 6.82 10.38666667 6.733333333 586 490 538 723.3333333 538 1.14E-04 -0.441774183 GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019003///GDP binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0006471///protein ADP-ribosylation+++GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016567///protein ubiquitination 81004 81004 'Tbl1xr1' mRNA 880.01 824 689.57 5.79 5.41 4.83 5.94 5.59 6.1 5.343333333 5.876666667 1051.2 939.87 995.03 797.86 995.3666667 0.002348651 0.309932009 04013///MAPK signaling pathway - fly+++04310///Wnt signaling pathway GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex+++GO:0072686///mitotic spindle GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0042393///histone binding+++GO:0047485///protein N-terminus binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001835///blastocyst hatching+++GO:0002021///response to dietary excess+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0016042///lipid catabolic process+++GO:0016575///histone deacetylation+++GO:0035264///multicellular organism growth+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050872///white fat cell differentiation+++GO:0060612///adipose tissue development+++GO:0060613///fat pad development+++GO:0090207///regulation of triglyceride metabolic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway" 81006 81006 'Gpr63' mRNA 307 338 374 1.63 1.64 1.92 1.3 1.06 0.9 1.73 1.086666667 283 236 199 339.6666667 239.3333333 0.003636018 -0.522847367 GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 81013 81013 'Vmn1r65' mRNA 16.59 11.49 10.87 0.34 0.23 0.24 0.19 0.14 0.05 0.27 0.126666667 10.61 7.48 2.49 12.98333333 6.86 0.317330662 -0.9739369 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 81014 81014 'Vmn1r58' mRNA 229.65 183.54 169.99 4.74 3.73 3.72 2.13 1.59 2.17 4.063333333 1.963333333 118.5 86.35 116.85 194.3933333 107.2333333 8.77E-05 -0.871254744 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 81016 81016 'Vmn1r62' mRNA 0 1 0 0 0.03 0 0 0 0 0.01 0 0 0 0 0.333333333 0 0.863090843 -0.97353728 GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0016503///pheromone receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008150///biological_process+++GO:0019236///response to pheromone 81018 81018 'Rnf114' mRNA 2724 2644 2673 70.3 66.88 72.81 79.41 82.58 79.02 69.99666667 80.33666667 3513 3569 3373 2680.333333 3485 5.71E-08 0.36634401 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation 81489 81489 'Dnajb1' mRNA 1862 2039 1949 33.92 36.56 37.71 29.79 25.53 26.17 36.06333333 27.16333333 1880 1575 1599 1950 1684.666667 0.010755164 -0.224974438 04141///Protein processing in endoplasmic reticulum+++05164///Influenza A GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0061827///sperm head+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099524///postsynaptic cytosol GO:0001671///ATPase activator activity+++GO:0003714///transcription corepressor activity+++GO:0030544///Hsp70 protein binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006457///protein folding+++GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0090084///negative regulation of inclusion body assembly+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress 81500 81500 'Sil1' mRNA 2167.02 2256 2270 72.92 76.43 82.31 66.95 70.54 70.05 77.22 69.18 2224 2291 2250 2231.006667 2255 0.984465571 0.002738417 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding GO:0015031///protein transport+++GO:0050790///regulation of catalytic activity 81535 81535 'Sgpp1' mRNA 811 852 551 13.31 13.76 9.59 8.84 7.32 8.57 12.22 8.243333333 620 501 582 738 567.6666667 0.007613096 -0.383404705 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0016787///hydrolase activity+++GO:0042392///sphingosine-1-phosphate phosphatase activity+++GO:0070780///dihydrosphingosine-1-phosphate phosphatase activity GO:0006665///sphingolipid metabolic process+++GO:0006668///sphinganine-1-phosphate metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0016311///dephosphorylation+++GO:0035621///ER to Golgi ceramide transport+++GO:0045616///regulation of keratinocyte differentiation+++GO:0045682///regulation of epidermis development+++GO:0046839///phospholipid dephosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway 81600 81600 'Chia1' mRNA 203 178 132 7.84 6.78 5.41 0.17 0.34 0.38 6.676666667 0.296666667 5 10 11 171 8.666666667 2.57E-29 -4.305520381 00520///Amino sugar and nucleotide sugar metabolism GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004568///chitinase activity+++GO:0008061///chitin binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0019900///kinase binding" GO:0000272///polysaccharide catabolic process+++GO:0001878///response to yeast+++GO:0002376///immune system process+++GO:0002532///production of molecular mediator involved in inflammatory response+++GO:0005975///carbohydrate metabolic process+++GO:0006032///chitin catabolic process+++GO:0006915///apoptotic process+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0008152///metabolic process+++GO:0032722///positive regulation of chemokine production+++GO:0052356///catabolism by host of symbiont cell wall chitin 81601 81601 'Kat5' mRNA 933 1073 853 27.19 30.87 26.42 17.79 21.22 18.33 28.16 19.11333333 705 818 705 953 742.6666667 0.001042101 -0.36690374 05017///Spinocerebellar ataxia+++05166///Human T-cell leukemia virus 1 infection GO:0000785///chromatin+++GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0032991///protein-containing complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0048471///perinuclear region of cytoplasm "GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0004402///histone acetyltransferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042393///histone binding+++GO:0043274///phospholipase binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0070491///repressing transcription factor binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006302///double-strand break repair+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0010212///response to ionizing radiation+++GO:0010508///positive regulation of autophagy+++GO:0016573///histone acetylation+++GO:0018394///peptidyl-lysine acetylation+++GO:0032703///negative regulation of interleukin-2 production+++GO:0040008///regulation of growth+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus+++GO:1901985///positive regulation of protein acetylation" 81630 81630 'Zbtb22' mRNA 225 179 190 4.79 3.75 4.29 4.35 3.92 3.98 4.276666667 4.083333333 235 207 208 198 216.6666667 0.611291581 0.117216114 GO:0005634///nucleus GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding GO:0006357///regulation of transcription by RNA polymerase II 81701 81701 'Egfl8' mRNA 1146.39 1111.09 1060.2 55.75 54 54.94 21.34 23.14 19.79 54.89666667 21.42333333 504.07 529.89 452.99 1105.893333 495.65 7.77E-32 -1.170404065 GO:0005576///extracellular region+++GO:0009986///cell surface GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding GO:0001701///in utero embryonic development+++GO:0048856///anatomical structure development 81702 81702 'Ankrd17' mRNA 1450 1438 1472 7.57 7.39 8.49 7.83 7.2 8 7.816666667 7.676666667 1630 1460 1577 1453.333333 1555.666667 0.383968849 0.084404085 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding GO:0001955///blood vessel maturation+++GO:0002376///immune system process+++GO:0006275///regulation of DNA replication+++GO:0007492///endoderm development+++GO:0042742///defense response to bacterium+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0045787///positive regulation of cell cycle+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:1900245///positive regulation of MDA-5 signaling pathway+++GO:1900246///positive regulation of RIG-I signaling pathway 81703 81703 'Jdp2' mRNA 21 31 25 0.61 0.89 0.85 1.4 0.91 1.16 0.783333333 1.156666667 46 32 43 25.66666667 40.33333333 0.184051091 0.639145739 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0035497///cAMP response element binding+++GO:0042803///protein homodimerization activity+++GO:0043522///leucine zipper domain binding+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031063///regulation of histone deacetylation+++GO:0031065///positive regulation of histone deacetylation+++GO:0045599///negative regulation of fat cell differentiation" 81799 81799 'C1qtnf3' mRNA 3 4 1 0.08 0.09 0.03 0.02 0.13 0.15 0.066666667 0.1 1 6 7 2.666666667 4.666666667 0.628510596 0.824083559 GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex GO:0042802///identical protein binding GO:0001819///positive regulation of cytokine production+++GO:0010629///negative regulation of gene expression+++GO:0032715///negative regulation of interleukin-6 production+++GO:0035356///cellular triglyceride homeostasis+++GO:0042593///glucose homeostasis+++GO:0045721///negative regulation of gluconeogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0070165///positive regulation of adiponectin secretion+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production+++GO:1901223///negative regulation of NIK/NF-kappaB signaling 81840 81840 'Sorcs2' mRNA 671.94 757.38 738.03 6.02 6.58 6.95 2.34 2.3 2.1 6.516666667 2.246666667 309.79 292.85 275.03 722.45 292.5566667 1.72E-27 -1.319478364 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043197///dendritic spine+++GO:0043204///perikaryon+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0055038///recycling endosome membrane+++GO:0098839///postsynaptic density membrane GO:0005515///protein binding GO:0006886///intracellular protein transport+++GO:0060292///long-term synaptic depression 81845 81845 'Gpank1' mRNA 545 494 587 22.05 19.71 24.8 18.78 17.66 16.65 22.18666667 17.69666667 522 487 438 542 482.3333333 0.218912716 -0.184675588 GO:0005575///cellular_component GO:0003676///nucleic acid binding+++GO:0005515///protein binding GO:0008150///biological_process 81877 81877 'Tnxb' mRNA 186 159 139 0.77 0.71 0.7 0.74 0.6 0.69 0.726666667 0.676666667 196 160 174 161.3333333 176.6666667 0.636398589 0.12093009 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++05165///Human papillomavirus infection+++05206///MicroRNAs in cancer GO:0001527///microfibril+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005518///collagen binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding+++GO:0098633///collagen fibril binding GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006641///triglyceride metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0030036///actin cytoskeleton organization+++GO:0030198///extracellular matrix organization+++GO:0030199///collagen fibril organization+++GO:0032963///collagen metabolic process+++GO:0043506///regulation of JUN kinase activity+++GO:0045785///positive regulation of cell adhesion+++GO:0048251///elastic fiber assembly+++GO:0098609///cell-cell adhesion 81879 81879 'Tfcp2l1' mRNA 409 364 336.01 2.31 2.02 2.02 1.91 1.44 1.82 2.116666667 1.723333333 388 287 359 369.67 344.6666667 0.544901063 -0.112970352 GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016020///membrane "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0002070///epithelial cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007028///cytoplasm organization+++GO:0007431///salivary gland development+++GO:0008340///determination of adult lifespan+++GO:0045927///positive regulation of growth+++GO:0045944///positive regulation of transcription by RNA polymerase II 81896 81896 'Ift122' mRNA 1585 1679 1770 21 21.89 24.91 8.27 9.32 8.36 22.6 8.65 720 791 702 1678 737.6666667 8.87E-35 -1.199455473 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0030991///intraciliary transport particle A+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0097546///ciliary base+++GO:0097730///non-motile cilium GO:0003674///molecular_function GO:0001843///neural tube closure+++GO:0007227///signal transduction downstream of smoothened+++GO:0007275///multicellular organism development+++GO:0009953///dorsal/ventral pattern formation+++GO:0010172///embryonic body morphogenesis+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0030030///cell projection organization+++GO:0035050///embryonic heart tube development+++GO:0035115///embryonic forelimb morphogenesis+++GO:0035720///intraciliary anterograde transport+++GO:0035721///intraciliary retrograde transport+++GO:0042073///intraciliary transport+++GO:0042733///embryonic digit morphogenesis+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0048593///camera-type eye morphogenesis+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060173///limb development+++GO:0060271///cilium assembly+++GO:0060830///ciliary receptor clustering involved in smoothened signaling pathway+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0061512///protein localization to cilium+++GO:0072594///establishment of protein localization to organelle+++GO:1905515///non-motile cilium assembly 81897 81897 'Tlr9' mRNA 10 11 1 0.16 0.17 0.02 0.45 0.26 0.49 0.116666667 0.4 33 19 35 7.333333333 29 0.005142686 1.990171131 04620///Toll-like receptor signaling pathway+++05132///Salmonella infection+++05142///Chagas disease+++05143///African trypanosomiasis+++05144///Malaria+++05152///Tuberculosis+++05162///Measles+++05168///Herpes simplex virus 1 infection+++05235///PD-L1 expression and PD-1 checkpoint pathway in cancer GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0032009///early phagosome+++GO:0036019///endolysosome+++GO:0045335///phagocytic vesicle GO:0003953///NAD+ nucleosidase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005515///protein binding+++GO:0035197///siRNA binding+++GO:0038187///pattern recognition receptor activity+++GO:0042803///protein homodimerization activity+++GO:0045322///unmethylated CpG binding GO:0001774///microglial cell activation+++GO:0001817///regulation of cytokine production+++GO:0001819///positive regulation of cytokine production+++GO:0001932///regulation of protein phosphorylation+++GO:0002218///activation of innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0002237///response to molecule of bacterial origin+++GO:0002376///immune system process+++GO:0002639///positive regulation of immunoglobulin production+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0007252///I-kappaB phosphorylation+++GO:0008584///male gonad development+++GO:0009615///response to virus+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0030890///positive regulation of B cell proliferation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032722///positive regulation of chemokine production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032728///positive regulation of interferon-beta production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032741///positive regulation of interleukin-18 production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0034163///regulation of toll-like receptor 9 signaling pathway+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045087///innate immune response+++GO:0045577///regulation of B cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050727///regulation of inflammatory response+++GO:0050729///positive regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050864///regulation of B cell activation+++GO:0050871///positive regulation of B cell activation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071248///cellular response to metal ion+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901895///negative regulation of calcium-transporting ATPase activity+++GO:1902350///cellular response to chloroquine 81898 81898 'Sf3b1' mRNA 7212 7429 6681 61.17 62.12 60.28 61.03 59.71 59.61 61.19 60.11666667 8154 7755 7649 7107.333333 7852.666667 0.012558552 0.133130919 03040///Spliceosome GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0005689///U12-type spliceosomal complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016363///nuclear matrix+++GO:0016607///nuclear speck+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0034693///U11/U12 snRNP+++GO:0071004///U2-type prespliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:1990935///splicing factor binding "GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001825///blastocyst formation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0009952///anterior/posterior pattern specification" 81904 81904 'Cacng7' mRNA 28 27 32 0.51 0.5 0.61 0.33 0.27 0.3 0.54 0.3 20 16 18 29 18 0.206888373 -0.705237007 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032281///AMPA glutamate receptor complex+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0044300///cerebellar mossy fiber+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity+++GO:0016247///channel regulator activity "GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0019226///transmission of nerve impulse+++GO:0034765///regulation of ion transmembrane transport+++GO:0043488///regulation of mRNA stability+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070588///calcium ion transmembrane transport+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099590///neurotransmitter receptor internalization+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:1903861///positive regulation of dendrite extension+++GO:2000311///regulation of AMPA receptor activity" 81905 81905 'Cacng8' mRNA 1 0 0 0.03 0 0 0 0.02 0 0.01 0.006666667 0 1 0 0.333333333 0.333333333 0.998591786 -0.011756601 04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy+++05412///Arrhythmogenic right ventricular cardiomyopathy+++05414///Dilated cardiomyopathy GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0032590///dendrite membrane+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098839///postsynaptic density membrane+++GO:0098978///glutamatergic synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:1990454///L-type voltage-gated calcium channel complex GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005262///calcium channel activity+++GO:0016247///channel regulator activity+++GO:0030346///protein phosphatase 2B binding+++GO:0035255///ionotropic glutamate receptor binding "GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0019226///transmission of nerve impulse+++GO:0034765///regulation of ion transmembrane transport+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0070588///calcium ion transmembrane transport+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0099590///neurotransmitter receptor internalization+++GO:2000311///regulation of AMPA receptor activity+++GO:2000969///positive regulation of AMPA receptor activity" 81906 81906 'Cyp4x1' mRNA 73.75 62.6 39.45 1 0.83 0.57 0.56 0.46 0.49 0.8 0.503333333 47.22 37.97 39.98 58.6 41.72333333 0.221267429 -0.504626329 04726///Serotonergic synapse GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0052722///fatty acid in-chain hydroxylase activity" 81907 81907 'Tmem108' mRNA 98 65 77 1.42 0.94 1.19 0.18 0.34 0.3 1.183333333 0.273333333 14 26 23 80 21 6.42E-07 -1.938386636 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0006898///receptor-mediated endocytosis+++GO:0008090///retrograde axonal transport+++GO:0021542///dentate gyrus development+++GO:0031175///neuron projection development+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0097106///postsynaptic density organization+++GO:0097484///dendrite extension+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus 81909 81909 'Zfpl1' mRNA 1137 1161 1021 49.99 50.25 47.84 43.43 47.19 42.79 49.36 44.47 1131 1188 1081 1106.333333 1133.333333 0.843953387 0.025371022 GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0008150///biological_process+++GO:0016192///vesicle-mediated transport 81910 81910 'Rrbp1' mRNA 2753 2743 2183 31.66 33.14 33.21 47.71 47.32 48.87 32.67 47.96666667 3614 3793 4010 2559.666667 3805.666667 3.67E-13 0.565792157 04141///Protein processing in endoplasmic reticulum GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0005515///protein binding GO:0007165///signal transduction+++GO:0015031///protein transport 83379 83379 'Klb' mRNA 4 4 2 0.04 0.04 0.02 0.1 0.07 0.06 0.033333333 0.076666667 12.03 9 7 3.333333333 9.343333333 0.178757248 1.479798892 04714///Thermogenesis GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0005104///fibroblast growth factor receptor binding+++GO:0005515///protein binding+++GO:0017134///fibroblast growth factor binding" GO:0005975///carbohydrate metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0090080///positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 83382 83382 'Siglece' mRNA 66 61 75 2.09 1.86 2.52 6.49 6.04 5.46 2.156666667 5.996666667 228 210 192 67.33333333 210 1.96E-13 1.625146391 GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0033691///sialic acid binding+++GO:0048029///monosaccharide binding "GO:0007155///cell adhesion+++GO:0050728///negative regulation of inflammatory response+++GO:0060101///negative regulation of phagocytosis, engulfment" 83383 83383 'Tfap4' mRNA 188 153 76 4.8 3.46 1.95 1.64 1.08 1.36 3.403333333 1.36 80 53 71 139 68 0.001338947 -1.03142869 05205///Proteoglycans in cancer GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0017053///transcriptional repressor complex "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0070888///E-box binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0008285///negative regulation of cell proliferation+++GO:0010629///negative regulation of gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043922///negative regulation by host of viral transcription+++GO:0043923///positive regulation by host of viral transcription+++GO:0044772///mitotic cell cycle phase transition+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0065003///protein-containing complex assembly+++GO:0071157///negative regulation of cell cycle arrest+++GO:0071549///cellular response to dexamethasone stimulus+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" 83395 83395 'Sp6' mRNA 138 154 146 2.23 2.4 2.5 1.09 0.89 0.99 2.376666667 0.99 79 62 68 146 69.66666667 7.95E-06 -1.081187585 GO:0005634///nucleus+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0042481///regulation of odontogenesis 83396 83396 'Glis2' mRNA 461 487 402 7.92 7.89 7.12 8.18 9.25 9.45 7.643333333 8.96 571 602 639 450 604 5.80E-04 0.416507723 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0097730///non-motile cilium "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007212///dopamine receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0007417///central nervous system development+++GO:0030154///cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060994///regulation of transcription from RNA polymerase II promoter involved in kidney development+++GO:0061005///cell differentiation involved in kidney development+++GO:0061484///hematopoietic stem cell homeostasis+++GO:1900182///positive regulation of protein localization to nucleus" 83397 83397 'Akap12' mRNA 2653 2579 2544 22.5 21.51 22.89 13.45 11.38 12.4 22.3 12.41 1826 1509 1631 2592 1655.333333 4.09E-18 -0.660592391 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0098685///Schaffer collateral - CA1 synapse GO:0005516///calmodulin binding+++GO:0008179///adenylate cyclase binding+++GO:0016301///kinase activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0051018///protein kinase A binding GO:0007165///signal transduction+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0010738///regulation of protein kinase A signaling+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0016310///phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035733///hepatic stellate cell activation+++GO:0043116///negative regulation of vascular permeability+++GO:0050804///modulation of chemical synaptic transmission+++GO:0051602///response to electrical stimulus+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0061870///positive regulation of hepatic stellate cell migration+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071347///cellular response to interleukin-1+++GO:0071356///cellular response to tumor necrosis factor+++GO:0090036///regulation of protein kinase C signaling+++GO:1900143///positive regulation of oligodendrocyte apoptotic process 83398 83398 'Ndst3' mRNA 27 24 31 0.44 0.27 0.58 0.11 0.05 0.09 0.43 0.083333333 10 3 6 27.33333333 6.333333333 0.001546214 -2.133261267 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003824///catalytic activity+++GO:0008146///sulfotransferase activity+++GO:0015016///[heparan sulfate]-glucosamine N-sulfotransferase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity+++GO:0102140///heparan sulfate N-deacetylase activity "GO:0008152///metabolic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0030210///heparin biosynthetic process" 83408 83408 'Gimap3' mRNA 9 11.03 18.7 0.24 0.29 0.52 1.43 1.09 1.13 0.35 1.216666667 62.31 46.49 47.89 12.91 52.23 3.20E-05 2.004258303 GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032585///multivesicular body membrane GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005525///GTP binding "GO:0000002///mitochondrial genome maintenance+++GO:0001659///temperature homeostasis+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032831///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation+++GO:0033955///mitochondrial DNA inheritance+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043029///T cell homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045838///positive regulation of membrane potential+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050868///negative regulation of T cell activation+++GO:0050995///negative regulation of lipid catabolic process" 83409 83409 'Lamtor2' mRNA 1707 1787 1711 225.98 237.6 244.67 247.09 302.81 269.81 236.0833333 273.2366667 2134 2556 2252 1735 2314 5.40E-06 0.405250352 04150///mTOR signaling pathway GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031143///pseudopodium+++GO:0031260///pseudopodium membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0071986///Ragulator complex GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031489///myosin V binding+++GO:0060090///molecular adaptor activity GO:0000186///activation of MAPKK activity+++GO:0001558///regulation of cell growth+++GO:0003382///epithelial cell morphogenesis+++GO:0006887///exocytosis+++GO:0008284///positive regulation of cell proliferation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0010761///fibroblast migration+++GO:0015031///protein transport+++GO:0031268///pseudopodium organization+++GO:0032008///positive regulation of TOR signaling+++GO:0034613///cellular protein localization+++GO:0043410///positive regulation of MAPK cascade+++GO:0050790///regulation of catalytic activity+++GO:0060627///regulation of vesicle-mediated transport+++GO:0071230///cellular response to amino acid stimulus+++GO:1902414///protein localization to cell junction 83410 83410 'Cstf2t' mRNA 1720 1862 1858 24.83 26.44 28.45 18.54 18.59 19.65 26.57333333 18.92666667 1478 1448 1517 1813.333333 1481 2.65E-04 -0.305265046 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0043231///intracellular membrane-bounded organelle GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing+++GO:0031124///mRNA 3'-end processing+++GO:0098789///pre-mRNA cleavage required for polyadenylation 83429 83429 'Ctns' mRNA 924 935 962 19.18 19.32 21.71 21.26 25.39 22.54 20.07 23.06333333 1153 1335 1170 940.3333333 1219.333333 4.28E-04 0.362913694 04142///Lysosome GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005774///vacuolar membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045111///intermediate filament cytoskeleton GO:0015184///L-cystine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0015295///solute:proton symporter activity GO:0002088///lens development in camera-type eye+++GO:0006749///glutathione metabolic process+++GO:0007420///brain development+++GO:0007616///long-term memory+++GO:0007625///grooming behavior+++GO:0007628///adult walking behavior+++GO:0008542///visual learning+++GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0015031///protein transport+++GO:0015811///L-cystine transport+++GO:0042438///melanin biosynthetic process+++GO:0046034///ATP metabolic process+++GO:0048021///regulation of melanin biosynthetic process+++GO:0050890///cognition+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1904263///positive regulation of TORC1 signaling 83430 83430 'Il23a' mRNA 2 0 0 0.09 0 0 0.58 0.28 0.28 0.03 0.38 15 7 7 0.666666667 9.666666667 0.013791218 3.847460759 04060///Cytokine-cytokine receptor interaction+++04625///C-type lectin receptor signaling pathway+++04630///JAK-STAT signaling pathway+++04659///Th17 cell differentiation+++05133///Pertussis+++05152///Tuberculosis+++05200///Pathways in cancer+++05321///Inflammatory bowel disease+++05323///Rheumatoid arthritis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0070743///interleukin-23 complex GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0045519///interleukin-23 receptor binding GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002376///immune system process+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0010536///positive regulation of activation of Janus kinase activity+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0032735///positive regulation of interleukin-12 production+++GO:0032740///positive regulation of interleukin-17 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0042098///T cell proliferation+++GO:0042102///positive regulation of T cell proliferation+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043382///positive regulation of memory T cell differentiation+++GO:0045087///innate immune response+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048771///tissue remodeling+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051135///positive regulation of NK T cell activation+++GO:0051142///positive regulation of NK T cell proliferation+++GO:0051607///defense response to virus+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:2000318///positive regulation of T-helper 17 type immune response+++GO:2000330///positive regulation of T-helper 17 cell lineage commitment 83431 83431 'Ndel1' mRNA 2099 2348 2189 48.75 53.68 54.03 43.09 45.5 43.59 52.15333333 44.06 2115 2185 2075 2212 2125 0.448124021 -0.069401757 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005635///nuclear envelope+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005875///microtubule associated complex+++GO:0008021///synaptic vesicle+++GO:0030424///axon+++GO:0031252///cell leading edge+++GO:0043203///axon hillock+++GO:0044297///cell body+++GO:0060053///neurofilament cytoskeleton+++GO:0090724///central region of growth cone+++GO:1904115///axon cytoplasm" GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0043014///alpha-tubulin binding+++GO:0044877///protein-containing complex binding+++GO:0048487///beta-tubulin binding+++GO:0070012///oligopeptidase activity GO:0000132///establishment of mitotic spindle orientation+++GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0001833///inner cell mass cell proliferation+++GO:0006508///proteolysis+++GO:0007020///microtubule nucleation+++GO:0007059///chromosome segregation+++GO:0007100///mitotic centrosome separation+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0008090///retrograde axonal transport+++GO:0008286///insulin receptor signaling pathway+++GO:0010975///regulation of neuron projection development+++GO:0016477///cell migration+++GO:0021799///cerebral cortex radially oriented cell migration+++GO:0021955///central nervous system neuron axonogenesis+++GO:0030154///cell differentiation+++GO:0031175///neuron projection development+++GO:0032418///lysosome localization+++GO:0033157///regulation of intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0045773///positive regulation of axon extension+++GO:0047496///vesicle transport along microtubule+++GO:0048680///positive regulation of axon regeneration+++GO:0051081///nuclear envelope disassembly+++GO:0051303///establishment of chromosome localization+++GO:0051642///centrosome localization+++GO:0060052///neurofilament cytoskeleton organization+++GO:0060070///canonical Wnt signaling pathway+++GO:0090630///activation of GTPase activity+++GO:1900029///positive regulation of ruffle assembly+++GO:1990138///neuron projection extension+++GO:2000574///regulation of microtubule motor activity 83433 83433 'Trem2' mRNA 123 121 116 7.01 6.82 7.02 196.93 195.03 191.39 6.95 194.45 3974 3838 3733 120 3848.333333 0 4.992030589 04380///Osteoclast differentiation GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0044853///plasma membrane raft GO:0001530///lipopolysaccharide binding+++GO:0001540///amyloid-beta binding+++GO:0001786///phosphatidylserine binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0008035///high-density lipoprotein particle binding+++GO:0008289///lipid binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0019209///kinase activator activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0034185///apolipoprotein binding+++GO:0034186///apolipoprotein A-I binding+++GO:0034189///very-low-density lipoprotein particle binding+++GO:0038023///signaling receptor activity+++GO:0042834///peptidoglycan binding+++GO:0044877///protein-containing complex binding+++GO:0070891///lipoteichoic acid binding+++GO:0071813///lipoprotein particle binding+++GO:0097110///scaffold protein binding+++GO:0120146///sulfatide binding+++GO:1990782///protein tyrosine kinase binding "GO:0001774///microglial cell activation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0002282///microglial cell activation involved in immune response+++GO:0002588///positive regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0002862///negative regulation of inflammatory response to antigenic stimulus+++GO:0002931///response to ischemia+++GO:0006910///phagocytosis, recognition+++GO:0006911///phagocytosis, engulfment+++GO:0007613///memory+++GO:0010468///regulation of gene expression+++GO:0010507///negative regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010822///positive regulation of mitochondrion organization+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0010891///negative regulation of sequestering of triglyceride+++GO:0010983///positive regulation of high-density lipoprotein particle clearance+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0019216///regulation of lipid metabolic process+++GO:0030316///osteoclast differentiation+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0032006///regulation of TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0032497///detection of lipopolysaccharide+++GO:0032499///detection of peptidoglycan+++GO:0032675///regulation of interleukin-6 production+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0033674///positive regulation of kinase activity+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0034151///regulation of toll-like receptor 6 signaling pathway+++GO:0034241///positive regulation of macrophage fusion+++GO:0034351///negative regulation of glial cell apoptotic process+++GO:0035176///social behavior+++GO:0038160///CXCL12-activated CXCR4 signaling pathway+++GO:0042742///defense response to bacterium+++GO:0043066///negative regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043277///apoptotic cell clearance+++GO:0045087///innate immune response+++GO:0045088///regulation of innate immune response+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045728///respiratory burst after phagocytosis+++GO:0045960///positive regulation of complement activation, classical pathway+++GO:0048143///astrocyte activation+++GO:0048678///response to axon injury+++GO:0050714///positive regulation of protein secretion+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0050766///positive regulation of phagocytosis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0050866///negative regulation of cell activation+++GO:0050921///positive regulation of chemotaxis+++GO:0055088///lipid homeostasis+++GO:0060075///regulation of resting membrane potential+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0061518///microglial cell proliferation+++GO:0061889///negative regulation of astrocyte activation+++GO:0070269///pyroptosis+++GO:0070345///negative regulation of fat cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0070392///detection of lipoteichoic acid+++GO:0071223///cellular response to lipoteichoic acid+++GO:0071224///cellular response to peptidoglycan+++GO:0071396///cellular response to lipid+++GO:0071640///regulation of macrophage inflammatory protein 1 alpha production+++GO:0097028///dendritic cell differentiation+++GO:0097062///dendritic spine maintenance+++GO:0097242///amyloid-beta clearance+++GO:0098657///import into cell+++GO:0110089///regulation of hippocampal neuron apoptotic process+++GO:0120035///regulation of plasma membrane bounded cell projection organization+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0150062///complement-mediated synapse pruning+++GO:0150076///neuroinflammatory response+++GO:0150078///positive regulation of neuroinflammatory response+++GO:0150079///negative regulation of neuroinflammatory response+++GO:0150094///amyloid-beta clearance by cellular catabolic process+++GO:1900015///regulation of cytokine production involved in inflammatory response+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:1900226///negative regulation of NLRP3 inflammasome complex assembly+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:1901980///positive regulation of inward rectifier potassium channel activity+++GO:1902227///negative regulation of macrophage colony-stimulating factor signaling pathway+++GO:1902531///regulation of intracellular signal transduction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1903082///positive regulation of C-C chemokine receptor CCR7 signaling pathway+++GO:1903376///regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1903753///negative regulation of p38MAPK cascade+++GO:1903980///positive regulation of microglial cell activation+++GO:1904093///negative regulation of autophagic cell death+++GO:1904141///positive regulation of microglial cell migration+++GO:1904646///cellular response to amyloid-beta+++GO:1904951///positive regulation of establishment of protein localization+++GO:1905291///positive regulation of CAMKK-AMPK signaling cascade+++GO:1905581///positive regulation of low-density lipoprotein particle clearance+++GO:1905805///excitatory synapse pruning+++GO:1905808///positive regulation of synapse pruning+++GO:1905907///negative regulation of amyloid fibril formation+++GO:2000350///positive regulation of CD40 signaling pathway+++GO:2001171///positive regulation of ATP biosynthetic process" 83435 83435 'Plekha3' mRNA 179 184 179 3.46 3.5 3.64 4.4 3.59 3.88 3.533333333 3.956666667 270 211 226 180.6666667 235.6666667 0.051369031 0.369460864 GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:1902387///ceramide 1-phosphate binding+++GO:1902388///ceramide 1-phosphate transporter activity GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0120009///intermembrane lipid transfer+++GO:1902389///ceramide 1-phosphate transport 83436 83436 'Plekha2' mRNA 547 604 537 5.74 6.3 6.02 13.16 15.15 12.99 6.02 13.76666667 1426 1602 1369 562.6666667 1465.666667 2.32E-44 1.371598571 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex "GO:0001968///fibronectin binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0030165///PDZ domain binding+++GO:0043236///laminin binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding" GO:0001954///positive regulation of cell-matrix adhesion 83453 83453 'Chrdl1' mRNA 1134 1340 1207 14.85 17.27 16.78 15.3 14.11 14.84 16.3 14.75 1353 1217 1271 1227 1280.333333 0.680686357 0.049119144 GO:0005576///extracellular region GO:0001503///ossification+++GO:0001654///eye development+++GO:0001709///cell fate determination+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0030182///neuron differentiation+++GO:0030514///negative regulation of BMP signaling pathway 83454 83454 'Nxf2' mRNA 3 2 2 0.07 0.06 0.05 0.21 0 0.09 0.06 0.1 9 0 4 2.333333333 4.333333333 0.648627483 0.866295913 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport+++03015///mRNA surveillance pathway+++05014///Amyotrophic lateral sclerosis+++05164///Influenza A+++05168///Herpes simplex virus 1 infection GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0051028///mRNA transport 83485 83485 'Ngrn' mRNA 1005 1105 1052 45.9 49.81 50.97 32.98 33.6 34.96 48.89333333 33.84666667 829 824 850 1054 834.3333333 2.36E-04 -0.349204283 GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016604///nuclear body+++GO:0031966///mitochondrial membrane+++GO:0045171///intercellular bridge+++GO:0072686///mitotic spindle GO:0019843///rRNA binding GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0070131///positive regulation of mitochondrial translation 83486 83486 'Rbm5' mRNA 5131 5289 5203 90.31 91.57 97.29 59.13 55.81 55.71 93.05666667 56.88333333 3881 3582 3535 5207.666667 3666 2.65E-17 -0.519723028 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0046872///metal ion binding "GO:0000245///spliceosomal complex assembly+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process" 83490 83490 'Pik3ap1' mRNA 1110 1129 1186 14.73 14.76 16.7 26.76 25.67 24.76 15.39666667 25.73 2318 2171 2076 1141.666667 2188.333333 1.21E-29 0.924339685 04151///PI3K-Akt signaling pathway+++04662///B cell receptor signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0003953///NAD+ nucleosidase activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0042802///identical protein binding GO:0007165///signal transduction+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043408///regulation of MAPK cascade+++GO:0050727///regulation of inflammatory response 83493 83493 'Sacm1l' mRNA 2088 2112 1936 31.83 31.67 31.3 26.87 25.79 27.4 31.6 26.68666667 2026 1895 1974 2045.333333 1965 0.392031462 -0.068874322 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0032281///AMPA glutamate receptor complex GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity GO:0008150///biological_process+++GO:0046856///phosphatidylinositol dephosphorylation 83553 83553 'Tktl1' mRNA 1 0 3 0.02 0 0.07 0 0 0 0.03 0 0 0 0 1.333333333 0 0.464551436 -2.917308793 00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0004802///transketolase activity+++GO:0016740///transferase activity+++GO:0030976///thiamine pyrophosphate binding+++GO:0046872///metal ion binding 83554 83554 'Fstl3' mRNA 398.82 404.37 375.64 11.66 11.65 11.65 10.54 10 10.97 11.65333333 10.50333333 414.49 383.99 417.56 392.9433333 405.3466667 0.862844268 0.03332812 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0044306///neuron projection terminus GO:0001968///fibronectin binding+++GO:0048185///activin binding GO:0001503///ossification+++GO:0001822///kidney development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008584///male gonad development+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0030325///adrenal gland development+++GO:0030510///regulation of BMP signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071248///cellular response to metal ion+++GO:0090101///negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 83555 83555 'Tex13b' mRNA 5 5 1 0.13 0.13 0.03 0.12 0.02 0.17 0.096666667 0.103333333 5 1 7 3.666666667 4.333333333 0.881166998 0.245474929 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 83557 83557 'Lin28a' mRNA 10 8 4 0.16 0.12 0.05 0.03 0.04 0.03 0.11 0.033333333 2 3 2 7.333333333 2.333333333 0.197496505 -1.648106277 GO:0000932///P-body+++GO:0005575///cellular_component+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0002151///G-quadruplex RNA binding+++GO:0003674///molecular_function+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0031369///translation initiation factor binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding+++GO:1905538///polysome binding+++GO:1990825///sequence-specific mRNA binding GO:0007281///germ cell development+++GO:0008150///biological_process+++GO:0010586///miRNA metabolic process+++GO:0010587///miRNA catabolic process+++GO:0017148///negative regulation of translation+++GO:0019827///stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0031054///pre-miRNA processing+++GO:0031123///RNA 3'-end processing+++GO:0032008///positive regulation of TOR signaling+++GO:0045666///positive regulation of neuron differentiation+++GO:0045686///negative regulation of glial cell differentiation+++GO:0045727///positive regulation of translation+++GO:0048863///stem cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060964///regulation of gene silencing by miRNA+++GO:0071076///RNA 3' uridylation+++GO:0071333///cellular response to glucose stimulus+++GO:1901724///positive regulation of cell proliferation involved in kidney development+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:2000767///positive regulation of cytoplasmic translation 83558 83558 'Tex11' mRNA 7 2 4 0.13 0.03 0.07 0.07 0.09 0.09 0.076666667 0.083333333 5 6 6 4.333333333 5.666666667 0.803288902 0.375715597 GO:0000794///condensed nuclear chromosome+++GO:0000795///synaptonemal complex+++GO:0000801///central element+++GO:0005694///chromosome GO:0005515///protein binding GO:0000712///resolution of meiotic recombination intermediates+++GO:0006311///meiotic gene conversion+++GO:0007060///male meiosis chromosome segregation+++GO:0007130///synaptonemal complex assembly+++GO:0007131///reciprocal meiotic recombination+++GO:0007140///male meiotic nuclear division+++GO:0008584///male gonad development+++GO:0009566///fertilization+++GO:0043066///negative regulation of apoptotic process+++GO:0051026///chiasma assembly+++GO:0051321///meiotic cell cycle 83560 83560 'Tex14' mRNA 16 15 14 0.19 0.17 0.17 0.24 0.21 0.06 0.176666667 0.17 24 20 6 15 16.66666667 0.87139847 0.137828312 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0045171///intercellular bridge" GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0007140///male meiotic nuclear division+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0032091///negative regulation of protein binding+++GO:0032466///negative regulation of cytokinesis+++GO:0043063///intercellular bridge organization+++GO:0051301///cell division+++GO:0051306///mitotic sister chromatid separation+++GO:1990830///cellular response to leukemia inhibitory factor 83561 83561 'Tdrd1' mRNA 0 2 3 0 0.02 0.04 0 0.02 0.01 0.02 0.01 0 2 1 1.666666667 1 0.806731513 -0.757439408 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0071546///pi-body+++GO:1990904///ribonucleoprotein complex GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007275///multicellular organism development+++GO:0007281///germ cell development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0030719///P granule organization+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0051321///meiotic cell cycle 83602 83602 'Gtf2a1' mRNA 1505 1503 1454 13.75 13.3 14.1 12.59 11.7 12.79 13.71666667 12.36 1577 1432 1555 1487.333333 1521.333333 0.863090843 0.020260874 03022///Basal transcription factors+++05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005672///transcription factor TFIIA complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097550///transcriptional preinitiation complex GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0046982///protein heterodimerization activity+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter 83603 83603 'Elovl4' mRNA 1036 1091 1058 18.61 19.29 20.16 7.92 8.02 8.01 19.35333333 7.983333333 507 502 497 1061.666667 502 8.22E-30 -1.092839459 00062///Fatty acid elongation+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane GO:0009922///fatty acid elongase activity+++GO:0016740///transferase activity+++GO:0102336///3-oxo-arachidoyl-CoA synthase activity+++GO:0102337///3-oxo-cerotoyl-CoA synthase activity+++GO:0102338///3-oxo-lignoceronyl-CoA synthase activity+++GO:0102756///very-long-chain 3-ketoacyl-CoA synthase activity "GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:0019367///fatty acid elongation, saturated fatty acid+++GO:0030148///sphingolipid biosynthetic process+++GO:0034625///fatty acid elongation, monounsaturated fatty acid+++GO:0034626///fatty acid elongation, polyunsaturated fatty acid+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process" 83669 83669 'Wdr6' mRNA 3218.49 3353.04 3441.56 41.92 42.96 47.55 28.72 29.25 29.03 44.14333333 29 2538.03 2525.2 2484.6 3337.696667 2515.943333 4.88E-09 -0.421405392 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008180///COP9 signalosome+++GO:0032991///protein-containing complex GO:0043560///insulin receptor substrate binding GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0010507///negative regulation of autophagy+++GO:0030488///tRNA methylation+++GO:0051726///regulation of cell cycle 83671 83671 'Sytl2' mRNA 701 727 746 6.64 7.03 7.66 8.75 8.31 8.23 7.11 8.43 984 892 917 724.6666667 931 6.25E-04 0.347451887 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0033162///melanosome membrane+++GO:0042470///melanosome+++GO:0070382///exocytic vesicle "GO:0001786///phosphatidylserine binding+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019902///phosphatase binding+++GO:0031267///small GTPase binding+++GO:0042043///neurexin family protein binding" GO:0006886///intracellular protein transport+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0010923///negative regulation of phosphatase activity+++GO:0070257///positive regulation of mucus secretion+++GO:0072659///protein localization to plasma membrane 83672 83672 'Sytl3' mRNA 121.26 112.76 155.15 2.71 2.72 3.78 1 1.08 0.85 3.07 0.976666667 47.69 49.22 42.35 129.7233333 46.42 1.35E-07 -1.510766145 GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0070382///exocytic vesicle GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0008270///zinc ion binding+++GO:0031267///small GTPase binding+++GO:0042043///neurexin family protein binding GO:0006886///intracellular protein transport+++GO:0006887///exocytosis 83674 83674 'Cnnm1' mRNA 1 2 1 0.01 0.02 0.01 0 0.01 0 0.013333333 0.003333333 0 1 0 1.333333333 0.333333333 0.57610831 -1.897845056 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0006811///ion transport+++GO:0010960///magnesium ion homeostasis+++GO:0055085///transmembrane transport 83675 83675 'Bicc1' mRNA 361 316 313 3.52 3.03 3.25 8.45 10.18 10.07 3.266666667 9.566666667 999 1175 1151 330 1108.333333 2.46E-51 1.738516457 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding GO:0001822///kidney development+++GO:0007275///multicellular organism development+++GO:0007368///determination of left/right symmetry+++GO:0007507///heart development+++GO:0090090///negative regulation of canonical Wnt signaling pathway 83679 83679 'Pde4dip' mRNA 4032 4259 4129 33.2 34.44 36.23 18.49 17.77 17.61 34.62333333 17.95666667 2573 2440 2387 4140 2466.666667 8.91E-33 -0.759914463 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0030016///myofibril+++GO:1903754///cortical microtubule plus-end GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0060090///molecular adaptor activity GO:0030953///astral microtubule organization+++GO:0034622///cellular protein-containing complex assembly+++GO:0090063///positive regulation of microtubule nucleation+++GO:1903358///regulation of Golgi organization 83691 83691 'Crispld1' mRNA 24.19 31.57 19.05 0.19 0.34 0.19 0.41 0.21 0.6 0.24 0.406666667 40.98 21.17 58.02 24.93666667 40.05666667 0.214515418 0.678374151 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0003674///molecular_function GO:0060325///face morphogenesis+++GO:0061484///hematopoietic stem cell homeostasis 83701 83701 'Srrt' mRNA 1486 1397 1060 26.08 24.13 21.1 24.44 22.61 22.65 23.77 23.23333333 1495 1366 1364 1314.333333 1408.333333 0.439147393 0.093048087 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:1990904///ribonucleoprotein complex "GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0030674///protein binding, bridging+++GO:0140262///mRNA cap binding complex binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0031047///gene silencing by RNA+++GO:0031053///primary miRNA processing+++GO:0050769///positive regulation of neurogenesis+++GO:0097150///neuronal stem cell population maintenance" 83703 83703 'Dbr1' mRNA 402 414 416 10.5 10.71 11.48 10.12 10.96 11 10.89666667 10.69333333 448 463 470 410.6666667 460.3333333 0.292756008 0.152477153 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0008419///RNA lariat debranching enzyme activity+++GO:0016787///hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding" "GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic" 83704 83704 'Slc12a9' mRNA 1158.99 1142.34 1171 16.77 16.2 18.06 16.32 14.04 15.55 17.01 15.30333333 1233 1048.06 1172.02 1157.443333 1151.026667 0.863090843 -0.021673319 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0015377///cation:chloride symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006884///cell volume homeostasis+++GO:0015698///inorganic anion transport+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:1990573///potassium ion import across plasma membrane 83762 83762 'Otof' mRNA 15595 15648 14760 119.97 118.34 120.29 9.66 7.98 9.08 119.5333333 8.906666667 1445 1169 1320 15334.33333 1311.333333 0 -3.560508595 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0045178///basal part of cell+++GO:0045202///synapse+++GO:0048787///presynaptic active zone membrane+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0098793///presynapse GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0001964///startle response+++GO:0007009///plasma membrane organization+++GO:0007605///sensory perception of sound+++GO:0016079///synaptic vesicle exocytosis+++GO:0016082///synaptic vesicle priming 83766 83766 'Actl6b' mRNA 175 145 150 7.76 6.6 7.31 1.07 0.56 0.99 7.223333333 0.873333333 27 16 23 156.6666667 22 3.29E-21 -2.846028963 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0016514///SWI/SNF complex+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071565///nBAF complex GO:0003682///chromatin binding+++GO:0005515///protein binding GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0016358///dendrite development+++GO:0021510///spinal cord development+++GO:0042551///neuron maturation+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0043967///histone H4 acetylation 83767 83767 'Wasf1' mRNA 1006 1047 361 20.93 21.49 8.17 3.04 3.91 4.13 16.86333333 3.693333333 162 208 220 804.6666667 196.6666667 2.44E-05 -2.019800737 04520///Adherens junction+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++05131///Shigellosis+++05231///Choline metabolism in cancer GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0032839///dendrite cytoplasm+++GO:0032991///protein-containing complex+++GO:0045202///synapse+++GO:0098794///postsynapse GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0031267///small GTPase binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051018///protein kinase A binding+++GO:0071933///Arp2/3 complex binding GO:0006898///receptor-mediated endocytosis+++GO:0016601///Rac protein signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0031175///neuron projection development+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0070584///mitochondrion morphogenesis+++GO:0072673///lamellipodium morphogenesis+++GO:0097484///dendrite extension+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:0098939///dendritic transport of mitochondrion+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation 83768 83768 'Dpp7' mRNA 1041 1023 1080 36.65 35.51 40.34 61.64 65.89 59.84 37.5 62.45666667 2012 2099 1890 1048 2000.333333 4.14E-27 0.919432604 GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity GO:0006508///proteolysis+++GO:1905146///lysosomal protein catabolic process 83770 83770 'Tas1r2' mRNA 2 0 0 0.04 0 0 0.02 0.02 0.02 0.013333333 0.02 1 1 1 0.666666667 1 0.863357859 0.593736086 04742///Taste transduction+++04973///Carbohydrate digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:1903767///sweet taste receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008527///taste receptor activity+++GO:0033041///sweet taste receptor activity GO:0001582///detection of chemical stimulus involved in sensory perception of sweet taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0050916///sensory perception of sweet taste 83771 83771 'Tas1r3' mRNA 30 31 20 0.46 0.47 0.33 0.36 0.17 0.37 0.42 0.3 27 12 27 27 22 0.654729079 -0.303906109 04742///Taste transduction+++04973///Carbohydrate digestion and absorption GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1903767///sweet taste receptor complex GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0008527///taste receptor activity+++GO:0033041///sweet taste receptor activity GO:0001582///detection of chemical stimulus involved in sensory perception of sweet taste+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0050916///sensory perception of sweet taste+++GO:0050917///sensory perception of umami taste 83796 83796 'Smarcd2' mRNA 757 809 557 17.13 17.83 13.75 11.62 11.89 12.99 16.23666667 12.16666667 574 576 625 707.6666667 591.6666667 0.050039446 -0.262772587 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex GO:0003712///transcription coregulator activity GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045944///positive regulation of transcription by RNA polymerase II 83797 83797 'Smarcd1' mRNA 898 908 466 15.63 15.54 8.69 6.08 8.62 7.06 13.28666667 7.253333333 399 558 452 757.3333333 469.6666667 0.048526589 -0.683135749 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0060090///molecular adaptor activity "GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0071398///cellular response to fatty acid" 83813 83813 'Tnk1' mRNA 448.24 466.62 409.83 7.61 7.79 7.7 3.23 3.17 3.23 7.7 3.21 219.16 203.06 212.09 441.5633333 211.4366667 6.80E-15 -1.071639686 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth+++GO:0045087///innate immune response+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0046777///protein autophosphorylation 83814 83814 'Nedd4l' mRNA 2191.66 2160 1958.99 13.02 12.77 12.38 8.71 7.99 8.17 12.72333333 8.29 1708.25 1514.01 1548.97 2103.55 1590.41 9.85E-09 -0.41458983 04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04530///Tight junction+++04960///Aldosterone-regulated sodium reabsorption GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005771///multivesicular body+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0015459///potassium channel regulator activity+++GO:0016740///transferase activity+++GO:0017080///sodium channel regulator activity+++GO:0019870///potassium channel inhibitor activity+++GO:0019871///sodium channel inhibitor activity+++GO:0044325///ion channel binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0003254///regulation of membrane depolarization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0009651///response to salt stress+++GO:0010038///response to metal ion+++GO:0010765///positive regulation of sodium ion transport+++GO:0010766///negative regulation of sodium ion transport+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0031647///regulation of protein stability+++GO:0034765///regulation of ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048814///regulation of dendrite morphogenesis+++GO:0060306///regulation of membrane repolarization+++GO:0070936///protein K48-linked ubiquitination+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:1902306///negative regulation of sodium ion transmembrane transport+++GO:1903861///positive regulation of dendrite extension+++GO:2000009///negative regulation of protein localization to cell surface+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:2000810///regulation of bicellular tight junction assembly+++GO:2001259///positive regulation of cation channel activity+++GO:2001288///positive regulation of caveolin-mediated endocytosis 83815 83815 'Cenpq' mRNA 243.25 297.7 270.96 3.33 3.93 3.89 2.74 3.08 2.94 3.716666667 2.92 230.75 252.01 239.04 270.6366667 240.6 0.351880723 -0.178942453 "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0015629///actin cytoskeleton+++GO:0031511///Mis6-Sim4 complex" GO:0051310///metaphase plate congression+++GO:1905342///positive regulation of protein localization to kinetochore 83885 83885 'Slc25a2' mRNA 2 4 2 0.09 0.18 0.09 0.16 0.08 0.32 0.12 0.186666667 4 2 8 2.666666667 4.666666667 0.625346119 0.802701436 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000064///L-ornithine transmembrane transporter activity GO:1990575///mitochondrial L-ornithine transmembrane transport 83921 83921 'Cemip2' mRNA 914 1008 950 7.3 7.92 8.04 6.57 5.47 6.14 7.753333333 6.06 948 771 858 957.3333333 859 0.125392978 -0.169942465 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004415///hyalurononglucosaminidase activity+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds" GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0008152///metabolic process+++GO:0030214///hyaluronan catabolic process+++GO:1903670///regulation of sprouting angiogenesis 83922 83922 'Cep41' mRNA 9472 9644 10234 155.16 155.55 177.99 68.96 67.98 64.65 162.9 67.19666667 4845 4666 4396 9783.333333 4635.666667 8.38E-58 -1.09251209 GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0003674///molecular_function GO:0015031///protein transport+++GO:0018095///protein polyglutamylation+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly 83924 83924 'Gpr137b' mRNA 1108 1112 1083 24.29 25.69 25.82 51.37 51.7 51.44 25.26666667 51.50333333 2183 2186 2202 1101 2190.333333 3.13E-41 0.980684768 GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0043030///regulation of macrophage activation+++GO:0043087///regulation of GTPase activity+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045779///negative regulation of bone resorption+++GO:0150032///positive regulation of protein localization to lysosome+++GO:1904263///positive regulation of TORC1 signaling 83925 83925 'Trps1' mRNA 535 533 527 2.28 2.25 2.52 2.48 2.26 2.54 2.35 2.426666667 684 600 669 531.6666667 651 0.015970482 0.279190481 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0019904///protein domain specific binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001942///hair follicle development+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0032330///regulation of chondrocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors" 83945 83945 'Dnaja3' mRNA 1771 1864 1830 38.62 40.08 42.4 33.03 34.13 33.5 40.36666667 33.55333333 1743 1761 1708 1821.666667 1737.333333 0.371840274 -0.080768492 05203///Viral carcinogenesis GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0005884///actin filament+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0042645///mitochondrial nucleoid+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane GO:0005133///interferon-gamma receptor binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0030695///GTPase regulator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0031072///heat shock protein binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0051082///unfolded protein binding+++GO:0106137///IkappaB kinase complex binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006264///mitochondrial DNA replication+++GO:0006457///protein folding+++GO:0006469///negative regulation of protein kinase activity+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006924///activation-induced cell death of T cells+++GO:0007005///mitochondrion organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0007528///neuromuscular junction development+++GO:0007569///cell aging+++GO:0008285///negative regulation of cell proliferation+++GO:0009408///response to heat+++GO:0009790///embryo development+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033077///T cell differentiation in thymus+++GO:0034341///response to interferon-gamma+++GO:0042102///positive regulation of T cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043069///negative regulation of programmed cell death+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050821///protein stabilization+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering 83946 83946 'Phip' mRNA 3253 3236 3027 15.8 15.45 15.6 8.25 7.78 8.03 15.61666667 8.02 1959 1802 1844 3172 1868.333333 2.72E-35 -0.775240139 GO:0005634///nucleus GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0070577///lysine-acetylated histone binding "GO:0001932///regulation of protein phosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0007010///cytoskeleton organization+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008360///regulation of cell shape+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0022604///regulation of cell morphogenesis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0040008///regulation of growth+++GO:0043066///negative regulation of apoptotic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 83961 83961 'Nrg4' mRNA 31.13 26.16 36.19 0.92 0.76 1.19 0.75 1.57 1.48 0.956666667 1.266666667 29.18 57.46 53.23 31.16 46.62333333 0.243634197 0.56776075 04012///ErbB signaling pathway+++05014///Amyotrophic lateral sclerosis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005102///signaling receptor binding+++GO:0008083///growth factor activity GO:0007399///nervous system development+++GO:0035556///intracellular signal transduction+++GO:0048513///animal organ development 83962 83962 'Btbd1' mRNA 904 922 675 16.42 16.51 13.02 15.33 12.88 16.09 15.31666667 14.76666667 972 797 985 833.6666667 918 0.333713406 0.131949904 GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0036464///cytoplasmic ribonucleoprotein granule GO:0042802///identical protein binding+++GO:0097602///cullin family protein binding GO:0007517///muscle organ development+++GO:0016567///protein ubiquitination+++GO:0022008///neurogenesis+++GO:0030154///cell differentiation 83964 83964 'Jam3' mRNA 2578 2621 2530 74.82 75.02 78.19 61.7 61.51 61.55 76.01 61.58666667 2426 2375 2355 2576.333333 2385.333333 0.084276995 -0.123099836 04514///Cell adhesion molecules+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05120///Epithelial cell signaling in Helicobacter pylori infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005902///microvillus+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030057///desmosome+++GO:0031941///filamentous actin+++GO:0033010///paranodal junction+++GO:0043220///Schmidt-Lanterman incisure+++GO:0044291///cell-cell contact zone+++GO:0070160///tight junction+++GO:0098636///protein complex involved in cell adhesion GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0098632///cell-cell adhesion mediator activity GO:0001525///angiogenesis+++GO:0001780///neutrophil homeostasis+++GO:0002250///adaptive immune response+++GO:0002318///myeloid progenitor cell differentiation+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0002693///positive regulation of cellular extravasation+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0007283///spermatogenesis+++GO:0007286///spermatid development+++GO:0016477///cell migration+++GO:0019226///transmission of nerve impulse+++GO:0030010///establishment of cell polarity+++GO:0030154///cell differentiation+++GO:0031103///axon regeneration+++GO:0033624///negative regulation of integrin activation+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0034113///heterotypic cell-cell adhesion+++GO:0034333///adherens junction assembly+++GO:0034394///protein localization to cell surface+++GO:0042552///myelination+++GO:0045176///apical protein localization+++GO:0090022///regulation of neutrophil chemotaxis+++GO:0090138///regulation of actin cytoskeleton organization by cell-cell adhesion+++GO:0097241///hematopoietic stem cell migration to bone marrow+++GO:0097530///granulocyte migration+++GO:0098609///cell-cell adhesion+++GO:1902414///protein localization to cell junction+++GO:1905710///positive regulation of membrane permeability 83965 83965 'Enpp5' mRNA 5893 5829 5806 112.54 109.88 119.16 61.69 56.76 61.17 113.86 59.87333333 3542 3215 3431 5842.666667 3396 1.46E-40 -0.79600087 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0000210///NAD+ diphosphatase activity+++GO:0003824///catalytic activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0007154///cell communication+++GO:0009166///nucleotide catabolic process 83984 83984 'Tssk6' mRNA 48.64 42.48 30.86 2.19 1.89 1.48 1.34 1.22 1.97 1.853333333 1.51 34.01 30.18 48.55 40.66 37.58 0.863090843 -0.104379466 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0030154///cell differentiation+++GO:0035092///sperm chromatin condensation+++GO:0035556///intracellular signal transduction 83993 83993 'Tbx19' mRNA 0 0 2 0 0 0.05 0 0.02 0 0.016666667 0.006666667 0 1 0 0.666666667 0.333333333 0.863090843 -0.975276534 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0001707///mesoderm formation+++GO:0001708///cell fate specification+++GO:0001756///somitogenesis+++GO:0003007///heart morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021983///pituitary gland development+++GO:0042127///regulation of cell proliferation+++GO:0045165///cell fate commitment+++GO:0045595///regulation of cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II" 83997 83997 'Slmap' mRNA 1553 1586 749 15 15.06 7.97 8.57 8.9 9.42 12.67666667 8.963333333 965 981 1078 1296 1008 0.340029911 -0.357516997 GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030018///Z disc+++GO:0031430///M band+++GO:0042383///sarcolemma GO:0005515///protein binding GO:0006936///muscle contraction+++GO:0072659///protein localization to plasma membrane+++GO:1900825///regulation of membrane depolarization during cardiac muscle cell action potential+++GO:1902305///regulation of sodium ion transmembrane transport+++GO:1905150///regulation of voltage-gated sodium channel activity 84004 84004 'Mcam' mRNA 485 497 520 9.35 9.37 10.57 22.56 18.37 19.25 9.763333333 20.06 1351 1073 1115 500.6666667 1179.666667 3.21E-29 1.220772947 GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001525///angiogenesis+++GO:0003094///glomerular filtration+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0030335///positive regulation of cell migration+++GO:0061042///vascular wound healing 84035 84035 'Kremen1' mRNA 5779.96 5639.05 4511 64.89 62.1 53.38 18.67 21.2 21.66 60.12333333 20.51 1917 2100 2115.59 5310.003333 2044.196667 1.69E-70 -1.383121616 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030279///negative regulation of ossification+++GO:0048681///negative regulation of axon regeneration+++GO:0060173///limb development+++GO:0090090///negative regulation of canonical Wnt signaling pathway 84036 84036 'Kcnn1' mRNA 174 194 122 2.86 3.36 2.28 2.24 2.03 1.52 2.833333333 1.93 137 126 101 163.3333333 121.3333333 0.080986075 -0.433584842 04911///Insulin secretion+++04929///GnRH secretion GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body GO:0005242///inward rectifier potassium channel activity+++GO:0005516///calmodulin binding+++GO:0015269///calcium-activated potassium channel activity+++GO:0016286///small conductance calcium-activated potassium channel activity+++GO:0044877///protein-containing complex binding GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport 84092 84092 'Usp8' mRNA 1782 1827 1936 22.95 23.13 26.43 22.22 22.02 20.91 24.17 21.71666667 1987 1921 1810 1848.333333 1906 0.800208843 0.029743541 04137///Mitophagy - animal+++04144///Endocytosis+++04934///Cushing syndrome GO:0002080///acrosomal membrane+++GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane+++GO:0030496///midbody+++GO:0031313///extrinsic component of endosome membrane+++GO:0043197///dendritic spine+++GO:0098978///glutamatergic synapse GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0017124///SH3 domain binding "GO:0000281///mitotic cytokinesis+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007032///endosome organization+++GO:0007049///cell cycle+++GO:0007265///Ras protein signal transduction+++GO:0016579///protein deubiquitination+++GO:0031647///regulation of protein stability+++GO:0032880///regulation of protein localization+++GO:0070536///protein K63-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:1990090///cellular response to nerve growth factor stimulus" 84094 84094 'Plvap' mRNA 66 59 71 1.82 1.61 2.09 5.29 7.59 7.53 1.84 6.803333333 218 303 299 65.33333333 273.3333333 4.24E-20 2.053570388 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm GO:0042802///identical protein binding GO:0000165///MAPK cascade+++GO:0002693///positive regulation of cellular extravasation+++GO:0032502///developmental process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0043114///regulation of vascular permeability 84095 84095 'Pi4k2a' mRNA 293 270 239 4.25 3.9 3.71 5.48 4.88 5.62 3.953333333 5.326666667 432 381 436 267.3333333 416.3333333 9.41E-06 0.629018756 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system GO:0005739///mitochondrion+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0030672///synaptic vesicle membrane+++GO:0031083///BLOC-1 complex+++GO:0031224///intrinsic component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0032991///protein-containing complex+++GO:0035838///growing cell tip+++GO:0042734///presynaptic membrane+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045121///membrane raft+++GO:0045202///synapse+++GO:0070382///exocytic vesicle GO:0000166///nucleotide binding+++GO:0004430///1-phosphatidylinositol 4-kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0035651///AP-3 adaptor complex binding+++GO:0044877///protein-containing complex binding GO:0002561///basophil degranulation+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0007030///Golgi organization+++GO:0007032///endosome organization+++GO:0016310///phosphorylation+++GO:0046854///phosphatidylinositol phosphorylation 84111 84111 'Gpr87' mRNA 2 2 1 0.08 0.08 0.04 0.18 0.18 0.07 0.066666667 0.143333333 5 5 2 1.666666667 4 0.471828131 1.259531857 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway 84112 84112 'Sucnr1' mRNA 17 16 24 0.64 0.59 0.95 0.75 0.8 0.4 0.726666667 0.65 23 24 12 19 19.66666667 0.975146162 0.028573286 04024///cAMP signaling pathway GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0038023///signaling receptor activity GO:0002001///renin secretion into blood stream+++GO:0002281///macrophage activation involved in immune response+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032611///interleukin-1 beta production+++GO:0042593///glucose homeostasis+++GO:0050729///positive regulation of inflammatory response+++GO:0050921///positive regulation of chemotaxis+++GO:0051592///response to calcium ion+++GO:0060177///regulation of angiotensin metabolic process 84113 84113 'Ptov1' mRNA 2205.56 2274.05 1018.41 69.82 70.42 30.77 26.98 24.27 30.65 57.00333333 27.3 1010.64 910.88 1120.9 1832.673333 1014.14 0.020036788 -0.849502673 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm GO:0045944///positive regulation of transcription by RNA polymerase II 84505 84505 'Setdb1' mRNA 669 637 655.97 7.76 7.27 8.07 10.21 8.28 8.33 7.7 8.94 1012.98 802.86 800.97 653.99 872.27 5.56E-04 0.399731995 00310///Lysine degradation+++04550///Signaling pathways regulating pluripotency of stem cells GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:1990841///promoter-specific chromatin binding GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001833///inner cell mass cell proliferation+++GO:0006325///chromatin organization+++GO:0007265///Ras protein signal transduction+++GO:0010629///negative regulation of gene expression+++GO:0032259///methylation+++GO:0033273///response to vitamin+++GO:0034968///histone lysine methylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0045471///response to ethanol+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0051567///histone H3-K9 methylation+++GO:0060348///bone development+++GO:0070828///heterochromatin organization+++GO:0090309///positive regulation of methylation-dependent chromatin silencing 84506 84506 'Hamp' mRNA 1 0 0 0.24 0 0 0 0.22 0.23 0.08 0.15 0 1 1 0.333333333 0.666666667 0.863090843 0.898150344 04350///TGF-beta signaling pathway GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0014704///intercalated disc+++GO:0045179///apical cortex GO:0005102///signaling receptor binding+++GO:0005179///hormone activity+++GO:0005507///copper ion binding+++GO:0097690///iron channel inhibitor activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002092///positive regulation of receptor internalization+++GO:0002262///myeloid cell homeostasis+++GO:0006879///cellular iron ion homeostasis+++GO:0007259///JAK-STAT cascade+++GO:0010039///response to iron ion+++GO:0031640///killing of cells of other organism+++GO:0031668///cellular response to extracellular stimulus+++GO:0032413///negative regulation of ion transmembrane transporter activity+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0042742///defense response to bacterium+++GO:0043032///positive regulation of macrophage activation+++GO:0045779///negative regulation of bone resorption+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050728///negative regulation of inflammatory response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050832///defense response to fungus+++GO:0055072///iron ion homeostasis+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:1902916///positive regulation of protein polyubiquitination+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:1904039///negative regulation of ferrous iron export+++GO:1904255///negative regulation of iron channel activity+++GO:1904479///negative regulation of intestinal absorption+++GO:2000646///positive regulation of receptor catabolic process 84544 84544 'Cd96' mRNA 24 25 35 0.64 0.64 1.03 0.43 0.44 0.33 0.77 0.4 18 19 14 28 17 0.205805135 -0.740145229 GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding GO:0002534///cytokine production involved in inflammatory response+++GO:0002728///negative regulation of natural killer cell cytokine production+++GO:0006954///inflammatory response+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0032496///response to lipopolysaccharide+++GO:0032689///negative regulation of interferon-gamma production 84585 84585 'Rnf123' mRNA 1568.56 1607.8 1536.81 17.86 17.99 18.71 11.26 11.69 9.44 18.18666667 10.79666667 1143.77 1141.08 942.88 1571.056667 1075.91 1.41E-09 -0.558316589 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0016567///protein ubiquitination+++GO:0051603///proteolysis involved in cellular protein catabolic process 84652 84652 'Fam126a' mRNA 334 342 367 3.63 3.11 4.05 4.7 4.32 4.72 3.596666667 4.58 558 521 551 347.6666667 543.3333333 7.93E-07 0.629816546 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043005///neuron projection GO:0003674///molecular_function GO:0042552///myelination+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0072659///protein localization to plasma membrane 84653 84653 'Hes7' mRNA 45 27 35 1.86 1.12 1.21 0.76 0.96 1.02 1.396666667 0.913333333 19 26 22 35.66666667 22.33333333 0.187072474 -0.686331735 05165///Human papillomavirus infection GO:0005634///nucleus "GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0001756///somitogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0036342///post-anal tail morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050767///regulation of neurogenesis" 84682 84682 'Cox4i2' mRNA 405 384 340 39.24 36.92 34.96 10.84 10.79 10.1 37.04 10.57666667 128 124 115 376.3333333 122.3333333 4.65E-24 -1.630898197 00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease+++05010///Alzheimer disease+++05012///Parkinson disease+++05014///Amyotrophic lateral sclerosis+++05016///Huntington disease+++05020///Prion disease+++05022///Pathways of neurodegeneration - multiple diseases+++05208///Chemical carcinogenesis - reactive oxygen species+++05415///Diabetic cardiomyopathy GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004129///cytochrome-c oxidase activity+++GO:0016491///oxidoreductase activity "GO:0006119///oxidative phosphorylation+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0071456///cellular response to hypoxia+++GO:1902600///proton transmembrane transport" 84704 84704 'Snurf' mRNA 871.38 909.36 867.57 24.53 25.22 25.91 14.47 16.68 15.09 25.22 15.41333333 590.94 665.01 596.44 882.77 617.4633333 5.03E-07 -0.526858924 GO:0005634///nucleus+++GO:0005685///U1 snRNP+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck GO:0051117///ATPase binding 85030 85030 'Tnfrsf25' mRNA 37 35 31 1.03 0.96 1.05 0.58 0.84 1.21 1.013333333 0.876666667 25 29 40 34.33333333 31.33333333 0.819224656 -0.13957062 04060///Cytokine-cytokine receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0006915///apoptotic process+++GO:0007165///signal transduction 85031 85031 'Pla1a' mRNA 27 34 37 0.85 0.98 1.28 3.53 4.1 3.45 1.036666667 3.693333333 126 139 122 32.66666667 129 1.60E-11 1.967881984 00564///Glycerophospholipid metabolism+++04014///Ras signaling pathway GO:0002080///acrosomal membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004806///triglyceride lipase activity+++GO:0008970///phospholipase A1 activity+++GO:0016298///lipase activity+++GO:0016787///hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process 85305 85305 'Kars' mRNA 2252 2295 2416 60.89 61.34 69.74 56.06 57.7 56.79 63.99 56.85 2368 2386 2329 2321 2361 0.917347823 0.010761488 00970///Aminoacyl-tRNA biosynthesis GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003877///ATP adenylyltransferase activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004824///lysine-tRNA ligase activity+++GO:0005524///ATP binding+++GO:0016597///amino acid binding+++GO:0016740///transferase activity+++GO:0016874///ligase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0097110///scaffold protein binding "GO:0002276///basophil activation involved in immune response+++GO:0002863///positive regulation of inflammatory response to antigenic stimulus+++GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006430///lysyl-tRNA aminoacylation+++GO:0010165///response to X-ray+++GO:0015966///diadenosine tetraphosphate biosynthetic process+++GO:0043032///positive regulation of macrophage activation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070371///ERK1 and ERK2 cascade" 85308 85308 'Emc9' mRNA 329 371 320 28.04 31.83 28.94 34.25 35.22 32.95 29.60333333 34.14 460 448 424 340 444 0.005382274 0.374609574 GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0072546///ER membrane protein complex GO:0032977///membrane insertase activity GO:0045050///protein insertion into ER membrane by stop-transfer membrane-anchor sequence+++GO:0071816///tail-anchored membrane protein insertion into ER membrane 89867 89867 'Sec16b' mRNA 27 20 31 0.33 0.23 0.41 0.3 0.19 0.19 0.323333333 0.226666667 28 17 17 26 20.66666667 0.591028926 -0.354775783 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070971///endoplasmic reticulum exit site GO:0003674///molecular_function GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0007029///endoplasmic reticulum organization+++GO:0007030///Golgi organization+++GO:0007031///peroxisome organization+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0016559///peroxisome fission+++GO:0048208///COPII vesicle coating+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0070973///protein localization to endoplasmic reticulum exit site 93670 93670 'Tac4' mRNA 4 6 5 0.19 0.29 0.26 0.08 0.39 0.13 0.246666667 0.2 2 9 3 5 4.666666667 0.948573412 -0.100341112 04080///Neuroactive ligand-receptor interaction GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0005102///signaling receptor binding+++GO:0031835///substance P receptor binding+++GO:0031837///substance K receptor binding+++GO:0048018///receptor ligand activity GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0006954///inflammatory response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007217///tachykinin receptor signaling pathway+++GO:0008217///regulation of blood pressure+++GO:0043303///mast cell degranulation+++GO:0046878///positive regulation of saliva secretion+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051930///regulation of sensory perception of pain+++GO:1902093///positive regulation of flagellated sperm motility+++GO:1904057///negative regulation of sensory perception of pain+++GO:1904058///positive regulation of sensory perception of pain 93671 93671 'Cd163' mRNA 120 108 129 1.46 1.28 1.65 2.55 2.23 2.41 1.463333333 2.396666667 242 206 222 119 223.3333333 6.86E-06 0.892191334 GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005044///scavenger receptor activity+++GO:0097110///scaffold protein binding GO:0006897///endocytosis+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response 93673 93673 'Nat8f2' mRNA 247.99 212.97 265.32 4.13 3.49 4.69 5.07 5.12 5.28 4.103333333 5.156666667 350.67 345.41 353.46 242.0933333 349.8466667 0.001569481 0.517841625 00480///Glutathione metabolism GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 93674 93674 'Nat8f3' mRNA 124.94 110.82 102.34 3.91 3.41 3.39 2.34 2.52 2.7 3.57 2.52 86.11 90.62 95.96 112.7 90.89666667 0.248203341 -0.319521581 00480///Glutathione metabolism GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0048471///perinuclear region of cytoplasm "GO:0004468///lysine N-acetyltransferase activity, acting on acetyl phosphate as donor+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0047198///cysteine-S-conjugate N-acetyltransferase activity" GO:0001702///gastrulation with mouth forming second+++GO:0003401///axis elongation+++GO:0006749///glutathione metabolic process+++GO:0007162///negative regulation of cell adhesion+++GO:0010628///positive regulation of gene expression+++GO:0016573///histone acetylation+++GO:0018003///peptidyl-lysine N6-acetylation+++GO:0043066///negative regulation of apoptotic process+++GO:0050435///amyloid-beta metabolic process 93675 93675 'Clec2i' mRNA 12 9 4 0.29 0.22 0.1 1.5 1.7 1.21 0.203333333 1.47 72 79 56 8.333333333 69 2.26E-10 3.046832401 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0046703///natural killer cell lectin-like receptor binding GO:0001765///membrane raft assembly+++GO:0030833///regulation of actin filament polymerization+++GO:0032663///regulation of interleukin-2 production+++GO:0042129///regulation of T cell proliferation+++GO:0043113///receptor clustering+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0050852///T cell receptor signaling pathway+++GO:2000522///positive regulation of immunological synapse formation 93679 93679 'Trim8' mRNA 860 870 711 17.17 17.38 15.66 17.63 15.19 18.2 16.73666667 17.00666667 945 783 935 813.6666667 887.6666667 0.34438185 0.116140395 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016605///PML body GO:0003713///transcription coactivator activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0002376///immune system process+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0032897///negative regulation of viral transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046597///negative regulation of viral entry into host cell+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1902187///negative regulation of viral release from host cell" 93681 93681 'Zkscan8' mRNA 548 523 428 4.79 4.03 3.58 1.72 2.68 2.76 4.133333333 2.386666667 299 365 393 499.6666667 352.3333333 6.29E-04 -0.509712838 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding" "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II" 93683 93683 'Glce' mRNA 1087 1142 1150 12.02 12.4 13.5 6.89 6.19 7.06 12.64 6.713333333 710 627 707 1126.333333 681.3333333 2.71E-14 -0.739094944 00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0005509///calcium ion binding+++GO:0016853///isomerase activity+++GO:0016857///racemase and epimerase activity, acting on carbohydrates and derivatives+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047464///heparosan-N-sulfate-glucuronate 5-epimerase activity+++GO:0050379///UDP-glucuronate 5'-epimerase activity" GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030210///heparin biosynthetic process 93684 93684 'Selenof' mRNA 8738 8935 8725 341.6 344.52 361.87 449.06 446.44 438.32 349.33 444.6066667 13195 12800 12460 8799.333333 12818.33333 4.67E-24 0.530172262 GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0005515///protein binding+++GO:0008379///thioredoxin peroxidase activity+++GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity GO:0035092///sperm chromatin condensation+++GO:0051084///'de novo' posttranslational protein folding+++GO:0098869///cellular oxidant detoxification 93685 93685 'Entpd7' mRNA 352.32 303.5 299.98 3.09 2.62 2.79 4.92 4.8 4.92 2.833333333 4.88 646.06 616.15 625.58 318.6 629.2633333 7.32E-16 0.97286023 GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle GO:0003924///GTPase activity+++GO:0004382///guanosine-diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0017110///nucleoside-diphosphatase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0043273///CTPase activity+++GO:0045134///uridine-diphosphatase activity+++GO:0046872///metal ion binding GO:0006254///CTP catabolic process+++GO:0006256///UDP catabolic process+++GO:0009134///nucleoside diphosphate catabolic process+++GO:0009191///ribonucleoside diphosphate catabolic process+++GO:0009203///ribonucleoside triphosphate catabolic process+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0046039///GTP metabolic process+++GO:0046052///UTP catabolic process+++GO:0050776///regulation of immune response+++GO:0072539///T-helper 17 cell differentiation 93686 93686 'Rbfox2' mRNA 832 827 643 6.74 6.64 5.34 5.81 5.31 6.28 6.24 5.8 820 683 841 767.3333333 781.3333333 0.904587643 0.018015675 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003676///nucleic acid binding+++GO:0003714///transcription corepressor activity+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding "GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007399///nervous system development+++GO:0008380///RNA splicing+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0043484///regulation of RNA splicing+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048813///dendrite morphogenesis+++GO:0050885///neuromuscular process controlling balance+++GO:0061337///cardiac conduction+++GO:0086091///regulation of heart rate by cardiac conduction" 93687 93687 'Csnk1a1' mRNA 4082 4135 3763 49.76 49.73 48.59 46.35 40.61 44.52 49.36 43.82666667 4357 3733 4057 3993.333333 4049 0.923295309 0.008225093 04310///Wnt signaling pathway+++04340///Hedgehog signaling pathway+++04341///Hedgehog signaling pathway - fly+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer "GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0016607///nuclear speck+++GO:0030877///beta-catenin destruction complex+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0045095///keratin filament+++GO:1990904///ribonucleoprotein complex" GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0042277///peptide binding+++GO:0051219///phosphoprotein binding GO:0000902///cell morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0016055///Wnt signaling pathway+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0051301///cell division+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1904424///regulation of GTP binding 93689 93689 'Lmod1' mRNA 761 682 476 10.43 9.19 6.92 2.52 2.52 2.3 8.846666667 2.446666667 212 207 187 639.6666667 202 1.56E-26 -1.666900206 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005865///striated muscle thin filament+++GO:0005884///actin filament+++GO:0030016///myofibril+++GO:0030017///sarcomere GO:0003779///actin binding+++GO:0005523///tropomyosin binding GO:0006936///muscle contraction+++GO:0007015///actin filament organization+++GO:0030239///myofibril assembly+++GO:0030838///positive regulation of actin filament polymerization+++GO:0045010///actin nucleation+++GO:0051694///pointed-end actin filament capping 93690 93690 'Gpr45' mRNA 3 2 1 0.03 0.03 0.01 0 0.01 0 0.023333333 0.003333333 0 1 0 2 0.333333333 0.380241534 -2.477853368 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway 93691 93691 'Klf7' mRNA 855 791 767 21.02 18.64 20.31 15.08 15.82 16.98 19.99 15.96 735 754 769 804.3333333 752.6666667 0.360744743 -0.106537852 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007409///axonogenesis+++GO:0007411///axon guidance+++GO:0042593///glucose homeostasis+++GO:0045604///regulation of epidermal cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048813///dendrite morphogenesis+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:1904178///negative regulation of adipose tissue development" 93692 93692 'Glrx' mRNA 917 923 920 41.66 41.4 44.35 61.82 66.37 66.62 42.47 64.93666667 1562 1636 1628 920 1608.666667 1.65E-21 0.794383369 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0043025///neuronal cell body GO:0004362///glutathione-disulfide reductase activity+++GO:0009055///electron transfer activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0015038///glutathione disulfide oxidoreductase activity+++GO:0019153///protein-disulfide reductase (glutathione) activity+++GO:0047485///protein N-terminus binding+++GO:0097573///glutathione oxidoreductase activity GO:0032024///positive regulation of insulin secretion+++GO:0045838///positive regulation of membrane potential+++GO:0045921///positive regulation of exocytosis+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0071392///cellular response to estradiol stimulus+++GO:0098869///cellular oxidant detoxification+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity 93694 93694 'Clec2d' mRNA 8 5 6 0.41 0.26 0.33 1.8 2.22 1 0.333333333 1.673333333 41 49 22 6.333333333 37.33333333 3.97E-05 2.548595716 GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0046703///natural killer cell lectin-like receptor binding GO:0006968///cellular defense response+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0045671///negative regulation of osteoclast differentiation 93695 93695 'Gpnmb' mRNA 2490 2449 2315 49.92 47.58 49.11 339.31 336.58 341.6 48.87 339.1633333 19991 19014 19182 2418 19395.66667 0 2.99243369 GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0033162///melanosome membrane GO:0005178///integrin binding+++GO:0008201///heparin binding+++GO:0045545///syndecan binding+++GO:0048018///receptor ligand activity GO:0001649///osteoblast differentiation+++GO:0001818///negative regulation of cytokine production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0007165///signal transduction+++GO:0007267///cell-cell signaling+++GO:0030282///bone mineralization+++GO:0030335///positive regulation of cell migration+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0034103///regulation of tissue remodeling+++GO:0042130///negative regulation of T cell proliferation+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901215///negative regulation of neuron death+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle 93696 93696 'Chrac1' mRNA 1023 1050 1065 80.31 81.65 88.73 62.38 63.7 55.01 83.56333333 60.36333333 910 905 775 1046 863.3333333 0.005616494 -0.290243252 GO:0005634///nucleus+++GO:0008623///CHRAC GO:0003677///DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046982///protein heterodimerization activity GO:0071897///DNA biosynthetic process 93697 93697 'Ice2' mRNA 262 302 300 3.38 3.9 3.98 3.28 2.96 2.68 3.753333333 2.973333333 288 249 234 288 257 0.345171248 -0.179028184 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0008023///transcription elongation factor complex+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0035327///transcriptionally active chromatin+++GO:0035363///histone locus body GO:0042795///snRNA transcription by RNA polymerase II+++GO:0042796///snRNA transcription by RNA polymerase III+++GO:0045945///positive regulation of transcription by RNA polymerase III 93699 93699 'Pcdhgb1' mRNA 442.58 471.95 454.16 5.06 5.31 5.51 1.76 1.79 1.68 5.293333333 1.743333333 177.35 175.88 163.45 456.23 172.2266667 5.09E-23 -1.420694067 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93700 93700 'Pcdhgb2' mRNA 184.77 159.36 218.19 2.14 1.81 2.68 0.99 0.88 1.02 2.21 0.963333333 98.51 85.17 97.75 187.44 93.81 9.72E-06 -1.021945886 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93701 93701 'Pcdhgb4' mRNA 372.76 399.11 343.57 4.29 4.52 4.19 2.33 2.28 2.32 4.333333333 2.31 232.7 222.79 225.24 371.8133333 226.91 5.43E-07 -0.724255528 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93702 93702 'Pcdhgb5' mRNA 329 283.79 271.42 3.75 3.18 3.28 1.86 1.79 2.22 3.403333333 1.956666667 188.2 177.01 217.7 294.7366667 194.3033333 3.77E-04 -0.611681513 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93703 93703 'Pcdhgb6' mRNA 895.08 952.04 887.86 10.24 10.71 10.77 6.98 6.27 6.72 10.57333333 6.656666667 702.45 616.33 655.58 911.66 658.12 7.86E-07 -0.482948697 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0008150///biological_process 93704 93704 'Pcdhgb7' mRNA 812.41 691.61 730.07 9.28 7.77 8.84 5.49 4.76 5.31 8.63 5.186666667 553.89 468.49 518.87 744.6966667 513.75 2.23E-06 -0.550540838 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93706 93706 'Pcdhgc3' mRNA 2275.76 2491.59 2376.96 26.01 28.01 28.82 37.28 39.3 37.27 27.61333333 37.95 3754.94 3866.91 3635.65 2381.436667 3752.5 6.57E-21 0.644264309 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050808///synapse organization 93707 93707 'Pcdhgc4' mRNA 271.78 290.27 274.06 2.89 3.03 3.09 3.23 2.25 2.98 3.003333333 2.82 349.66 238.44 312.05 278.7033333 300.05 0.676907845 0.091983998 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050808///synapse organization 93708 93708 'Pcdhgc5' mRNA 211.37 231.68 162.84 2.4 2.59 1.97 8.6 7.76 7.52 2.32 7.96 870.34 767.54 737.22 201.9633333 791.7 8.57E-51 1.966753654 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050808///synapse organization 93709 93709 'Pcdhga1' mRNA 89.3 135.63 93.58 1.02 1.52 1.13 0.57 0.35 0.6 1.223333333 0.506666667 57.6 34.18 58.34 106.17 50.04 5.89E-04 -1.099090979 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93710 93710 'Pcdhga2' mRNA 267.39 312.92 268.16 3.04 3.5 3.23 0.83 1.05 1.05 3.256666667 0.976666667 84 104.31 102.76 282.8233333 97.02333333 2.76E-16 -1.555087603 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93711 93711 'Pcdhga3' mRNA 153.07 163.19 127.37 1.75 1.83 1.54 0.72 0.51 0.41 1.706666667 0.546666667 72.13 50.38 40.4 147.8766667 54.30333333 7.08E-08 -1.462168798 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0008333///endosome to lysosome transport+++GO:0060989///lipid tube assembly involved in organelle fusion 93712 93712 'Pcdhga4' mRNA 257.96 289.44 301.1 2.94 3.25 3.64 2.07 2.39 1.48 3.276666667 1.98 208.9 235.81 144.26 282.8333333 196.3233333 0.008885124 -0.543085726 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007283///spermatogenesis 93713 93713 'Pcdhga5' mRNA 306.21 267.53 244.01 3.52 3.02 2.97 1.33 1.5 1.32 3.17 1.383333333 133.16 146.57 127.72 272.5833333 135.8166667 1.68E-08 -1.017692392 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93714 93714 'Pcdhga6' mRNA 269.53 238.3 253.84 3.09 2.69 3.09 1.68 2.13 1.51 2.956666667 1.773333333 168.15 208.9 146.69 253.89 174.58 0.005006613 -0.553321398 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93715 93715 'Pcdhga7' mRNA 1232.11 1175.34 1129.75 14.17 13.29 13.78 6.49 6.37 5.99 13.74666667 6.283333333 649.99 622.55 580.52 1179.066667 617.6866667 6.06E-25 -0.945444576 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93716 93716 'Pcdhga8' mRNA 479.13 423.44 444.36 5.42 4.71 5.34 2.91 3.32 2.2 5.156666667 2.81 295.42 329.8 216.5 448.9766667 280.5733333 3.19E-05 -0.692404415 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0008150///biological_process 93717 93717 'Pcdhga9' mRNA 204.66 228.18 209.82 2.32 2.55 2.53 1.92 2.01 2.12 2.466666667 2.016666667 194.81 198.69 207.9 214.22 200.4666667 0.625923547 -0.10875999 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007283///spermatogenesis 93719 93719 'Ear6' mRNA 1 0 0 0.1 0 0 0 0.09 0.09 0.033333333 0.06 0 1 1 0.333333333 0.666666667 0.863090843 0.898150344 GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0002227///innate immune response in mucosa+++GO:0006935///chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 93721 93721 'Cpn1' mRNA 3 0 1 0.1 0 0.03 0.03 0 0.12 0.043333333 0.05 1 0 4 1.333333333 1.666666667 0.91265126 0.310617362 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006508///proteolysis+++GO:0006518///peptide metabolic process+++GO:0010815///bradykinin catabolic process+++GO:0016485///protein processing+++GO:0051384///response to glucocorticoid 93722 93722 'Pcdhga10' mRNA 208.82 193.29 242.37 2.38 2.16 2.93 2.15 1.8 1.95 2.49 1.966666667 217.43 178.23 190.68 214.8266667 195.4466667 0.507751508 -0.154785036 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93723 93723 'Pcdhga11' mRNA 525.14 588.02 494.89 5.97 6.57 5.96 3.24 3.77 2.43 6.166666667 3.146666667 328.11 373.38 238.48 536.0166667 313.3233333 8.47E-07 -0.784023259 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93724 93724 'Pcdhga12' mRNA 274.48 272.93 258.83 2.88 2.82 2.89 1.88 2.03 1.74 2.863333333 1.883333333 206.25 217.68 184.24 268.7466667 202.7233333 0.015907414 -0.416470298 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 93725 93725 'Ear10' mRNA 0.99 0 0 0.1 0 0 0.46 0.79 0.45 0.033333333 0.566666667 5.11 8.58 4.87 0.33 6.186666667 0.010839136 4.937334065 GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0002227///innate immune response in mucosa+++GO:0006935///chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 93726 93726 'Rnase2a' mRNA 13 19 17 1.35 1.96 1.88 1.09 0.75 0.94 1.73 0.926666667 12 8 10 16.33333333 10 0.353682939 -0.723141707 GO:0005615///extracellular space GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004519///endonuclease activity+++GO:0004540///ribonuclease activity+++GO:0016787///hydrolase activity GO:0002227///innate immune response in mucosa+++GO:0006935///chemotaxis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis 93728 93728 'Pabpc5' mRNA 0 1 1 0 0.02 0.02 0 0 0 0.013333333 0 0 0 0 0.666666667 0 0.747865658 -1.883366447 03015///mRNA surveillance pathway+++03018///RNA degradation GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0008143///poly(A) binding+++GO:0008266///poly(U) RNA binding GO:0008150///biological_process 93730 93730 'Lztfl1' mRNA 1417 1439 1404 11.22 11.2 11.79 6.15 5.77 5.3 11.40333333 5.74 895 820 746 1420 820.3333333 3.22E-19 -0.804642044 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding GO:1903565///negative regulation of protein localization to cilium+++GO:1903568///negative regulation of protein localization to ciliary membrane 93732 93732 'Acox2' mRNA 136 175 146 2.96 3.67 3.32 3.84 3.98 4.48 3.316666667 4.1 200 199 227 152.3333333 208.6666667 0.029087976 0.44396794 00120///Primary bile acid biosynthesis+++03320///PPAR signaling pathway+++04146///Peroxisome GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle "GO:0003997///acyl-CoA oxidase activity+++GO:0005504///fatty acid binding+++GO:0016401///palmitoyl-CoA oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0033791///3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity+++GO:0042803///protein homodimerization activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding" GO:0000038///very long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0010942///positive regulation of cell death+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0055088///lipid homeostasis+++GO:1902884///positive regulation of response to oxidative stress 93734 93734 'Mpv17l' mRNA 886.08 881.35 972.05 14.45 14.14 16.79 12.17 12.46 12.99 15.12666667 12.54 836.7 832.88 871.22 913.16 846.9333333 0.304101872 -0.123981202 04146///Peroxisome GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0072593///reactive oxygen species metabolic process+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 93735 93735 'Wnt16' mRNA 87 97 74 2.9 3.28 2.65 12.84 10.9 13.59 2.943333333 12.44333333 438 371 449 86 419.3333333 1.72E-39 2.276159227 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding+++GO:0005125///cytokine activity GO:0007275///multicellular organism development+++GO:0010628///positive regulation of gene expression+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0030216///keratinocyte differentiation+++GO:0043616///keratinocyte proliferation+++GO:0045165///cell fate commitment+++GO:0046330///positive regulation of JNK cascade+++GO:0046849///bone remodeling+++GO:0060070///canonical Wnt signaling pathway+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060548///negative regulation of cell death+++GO:0090399///replicative senescence+++GO:0090403///oxidative stress-induced premature senescence 93736 93736 'Aff4' mRNA 2323 2410 1856 12.23 12.45 10.48 8.86 8.29 8.9 11.72 8.683333333 1924 1755 1866 2196.333333 1848.333333 0.002369421 -0.256342581 GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008023///transcription elongation factor complex+++GO:0032783///ELL-EAF complex+++GO:0035327///transcriptionally active chromatin GO:0005515///protein binding GO:0007286///spermatid development+++GO:0010468///regulation of gene expression 93737 93737 'Pard6g' mRNA 482 460 403 8.48 7.96 7.45 6.93 7.69 8.18 7.963333333 7.6 454 496 522 448.3333333 490.6666667 0.419608907 0.121904298 04015///Rap1 signaling pathway+++04144///Endocytosis+++04360///Axon guidance+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0005938///cell cortex+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0032991///protein-containing complex GO:0005080///protein kinase C binding GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0007163///establishment or maintenance of cell polarity+++GO:0051301///cell division+++GO:0060341///regulation of cellular localization 93739 93739 'Gabarapl2' mRNA 5128 5045 4926 336.23 327.19 342.72 287.3 284.52 287.73 335.38 286.5166667 5023 4848 4861 5033 4910.666667 0.493082977 -0.047638059 04068///FoxO signaling pathway+++04136///Autophagy - other+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04212///Longevity regulating pathway - worm+++04621///NOD-like receptor signaling pathway+++04727///GABAergic synapse GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006914///autophagy+++GO:0006995///cellular response to nitrogen starvation+++GO:0015031///protein transport+++GO:0016236///macroautophagy+++GO:0070972///protein localization to endoplasmic reticulum+++GO:1901799///negative regulation of proteasomal protein catabolic process 93742 93742 'Pard3' mRNA 507 542 347 5.08 5.25 3.74 3.01 2.71 2.84 4.69 2.853333333 338 284 308 465.3333333 310 2.08E-04 -0.59068309 04015///Rap1 signaling pathway+++04062///Chemokine signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04144///Endocytosis+++04360///Axon guidance+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04520///Adherens junction+++04530///Tight junction+++05165///Human papillomavirus infection GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005912///adherens junction+++GO:0005923///bicellular tight junction+++GO:0005929///cilium+++GO:0005930///axoneme+++GO:0005938///cell cortex+++GO:0012505///endomembrane system+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0032991///protein-containing complex+++GO:0033269///internode region of axon+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043219///lateral loop+++GO:0043220///Schmidt-Lanterman incisure+++GO:0043296///apical junction complex+++GO:0044295///axonal growth cone+++GO:0045177///apical part of cell "GO:0005102///signaling receptor binding+++GO:0005158///insulin receptor binding+++GO:0005184///neuropeptide hormone activity+++GO:0005515///protein binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0008289///lipid binding+++GO:0019903///protein phosphatase binding+++GO:0031779///melanocortin receptor binding+++GO:0031781///type 3 melanocortin receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0070577///lysine-acetylated histone binding" "GO:0000226///microtubule cytoskeleton organization+++GO:0001932///regulation of protein phosphorylation+++GO:0002092///positive regulation of receptor internalization+++GO:0003383///apical constriction+++GO:0006091///generation of precursor metabolites and energy+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus+++GO:0006612///protein targeting to membrane+++GO:0006886///intracellular protein transport+++GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0007155///cell adhesion+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007507///heart development+++GO:0008104///protein localization+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0008343///adult feeding behavior+++GO:0008360///regulation of cell shape+++GO:0008589///regulation of smoothened signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0022011///myelination in peripheral nervous system+++GO:0022604///regulation of cell morphogenesis+++GO:0030010///establishment of cell polarity+++GO:0030154///cell differentiation+++GO:0031643///positive regulation of myelination+++GO:0032402///melanosome transport+++GO:0032438///melanosome organization+++GO:0032970///regulation of actin filament-based process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035264///multicellular organism growth+++GO:0040008///regulation of growth+++GO:0040030///regulation of molecular function, epigenetic+++GO:0042438///melanin biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043473///pigmentation+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0044319///wound healing, spreading of cells+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0051301///cell division+++GO:0051642///centrosome localization+++GO:0051660///establishment of centrosome localization+++GO:0060271///cilium assembly+++GO:0060322///head development+++GO:0060341///regulation of cellular localization+++GO:0070830///bicellular tight junction assembly+++GO:0071514///genetic imprinting+++GO:0090162///establishment of epithelial cell polarity+++GO:0098609///cell-cell adhesion+++GO:0099041///vesicle tethering to Golgi+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway" 93746 93746 'Gprc5d' mRNA 0 1 1 0 0.05 0.05 0 0.04 0 0.033333333 0.013333333 0 1 0 0.666666667 0.333333333 0.861179337 -0.920394634 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0070062///extracellular exosome GO:0003674///molecular_function+++GO:0004930///G protein-coupled receptor activity+++GO:0030295///protein kinase activator activity GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031424///keratinization+++GO:0032147///activation of protein kinase activity+++GO:0042633///hair cycle 93747 93747 'Echs1' mRNA 1544 1517 1472 60.73 58.85 61.43 59.34 63.59 62.76 60.33666667 61.89666667 1733 1812 1773 1511 1772.666667 0.005741274 0.219274166 "00062///Fatty acid elongation+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++00650///Butanoate metabolism+++01200///Carbon metabolism+++01212///Fatty acid metabolism" GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix GO:0003824///catalytic activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0016829///lyase activity+++GO:0043956///3-hydroxypropionyl-CoA dehydratase activity+++GO:0120092///crotonyl-CoA hydratase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation 93757 93757 'Immp2l' mRNA 139 169 142 8.05 8.8 8.01 1.35 1.26 1.62 8.286666667 1.41 30 26 27 150 27.66666667 4.86E-18 -2.449612352 03060///Protein export GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042720///mitochondrial inner membrane peptidase complex GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity GO:0001541///ovarian follicle development+++GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0006627///protein processing involved in protein targeting to mitochondrion+++GO:0006801///superoxide metabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0008015///blood circulation+++GO:0008104///protein localization+++GO:0022904///respiratory electron transport chain+++GO:0030728///ovulation+++GO:0033108///mitochondrial respiratory chain complex assembly+++GO:0061300///cerebellum vasculature development 93759 93759 'Sirt1' mRNA 166 191 181 2.34 2.68 2.74 2.48 1.94 2.45 2.586666667 2.29 200 154 192 179.3333333 182 0.983461196 0.007305857 00760///Nicotinate and nicotinamide metabolism+++04068///FoxO signaling pathway+++04152///AMPK signaling pathway+++04211///Longevity regulating pathway+++04212///Longevity regulating pathway - worm+++04213///Longevity regulating pathway - multiple species+++04218///Cellular senescence+++04922///Glucagon signaling pathway+++04936///Alcoholic liver disease+++05031///Amphetamine addiction+++05206///MicroRNAs in cancer GO:0000785///chromatin+++GO:0000791///euchromatin+++GO:0000792///heterochromatin+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0033553///rDNA heterochromatin+++GO:0035098///ESC/E(Z) complex GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0002039///p53 binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0016922///nuclear receptor binding+++GO:0017136///NAD-dependent histone deacetylase activity+++GO:0019213///deacetylase activity+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0033558///protein deacetylase activity+++GO:0034979///NAD-dependent protein deacetylase activity+++GO:0042393///histone binding+++GO:0042802///identical protein binding+++GO:0043398///HLH domain binding+++GO:0043422///protein kinase B binding+++GO:0043425///bHLH transcription factor binding+++GO:0046872///metal ion binding+++GO:0046969///NAD-dependent histone deacetylase activity (H3-K9 specific)+++GO:0051019///mitogen-activated protein kinase binding+++GO:0070403///NAD+ binding+++GO:1990254///keratin filament binding+++GO:1990841///promoter-specific chromatin binding "GO:0000012///single strand break repair+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000183///chromatin silencing at rDNA+++GO:0000720///pyrimidine dimer repair by nucleotide-excision repair+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0001525///angiogenesis+++GO:0001542///ovulation from ovarian follicle+++GO:0001678///cellular glucose homeostasis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002821///positive regulation of adaptive immune response+++GO:0006325///chromatin organization+++GO:0006476///protein deacetylation+++GO:0006642///triglyceride mobilization+++GO:0006915///apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006979///response to oxidative stress+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0007346///regulation of mitotic cell cycle+++GO:0007517///muscle organ development+++GO:0007623///circadian rhythm+++GO:0008284///positive regulation of cell proliferation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009267///cellular response to starvation+++GO:0010460///positive regulation of heart rate+++GO:0010629///negative regulation of gene expression+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0010824///regulation of centrosome duplication+++GO:0010875///positive regulation of cholesterol efflux+++GO:0010883///regulation of lipid storage+++GO:0010906///regulation of glucose metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0014858///positive regulation of skeletal muscle cell proliferation+++GO:0016239///positive regulation of macroautophagy+++GO:0016567///protein ubiquitination+++GO:0016575///histone deacetylation+++GO:0018394///peptidyl-lysine acetylation+++GO:0030154///cell differentiation+++GO:0030225///macrophage differentiation+++GO:0030308///negative regulation of cell growth+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0031507///heterochromatin assembly+++GO:0031648///protein destabilization+++GO:0032007///negative regulation of TOR signaling+++GO:0032071///regulation of endodeoxyribonuclease activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032868///response to insulin+++GO:0032922///circadian regulation of gene expression+++GO:0033210///leptin-mediated signaling pathway+++GO:0034391///regulation of smooth muscle cell apoptotic process+++GO:0034983///peptidyl-lysine deacetylation+++GO:0035356///cellular triglyceride homeostasis+++GO:0035358///regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042127///regulation of cell proliferation+++GO:0042311///vasodilation+++GO:0042326///negative regulation of phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0042595///behavioral response to starvation+++GO:0042632///cholesterol homeostasis+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043392///negative regulation of DNA binding+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0044321///response to leptin+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0045471///response to ethanol+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045722///positive regulation of gluconeogenesis+++GO:0045739///positive regulation of DNA repair+++GO:0045766///positive regulation of angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0050872///white fat cell differentiation+++GO:0051097///negative regulation of helicase activity+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0055089///fatty acid homeostasis+++GO:0060125///negative regulation of growth hormone secretion+++GO:0060548///negative regulation of cell death+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0061647///histone H3-K9 modification+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070829///heterochromatin maintenance+++GO:0070857///regulation of bile acid biosynthetic process+++GO:0070914///UV-damage excision repair+++GO:0070932///histone H3 deacetylation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071441///negative regulation of histone H3-K14 acetylation+++GO:0071456///cellular response to hypoxia+++GO:0071479///cellular response to ionizing radiation+++GO:0071900///regulation of protein serine/threonine kinase activity+++GO:0090312///positive regulation of protein deacetylation+++GO:0090335///regulation of brown fat cell differentiation+++GO:0090400///stress-induced premature senescence+++GO:0097009///energy homeostasis+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:1900181///negative regulation of protein localization to nucleus+++GO:1901215///negative regulation of neuron death+++GO:1901984///negative regulation of protein acetylation+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:1904179///positive regulation of adipose tissue development+++GO:1904646///cellular response to amyloid-beta+++GO:1990619///histone H3-K9 deacetylation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity+++GO:2000614///positive regulation of thyroid-stimulating hormone secretion+++GO:2000619///negative regulation of histone H4-K16 acetylation+++GO:2000655///negative regulation of cellular response to testosterone stimulus+++GO:2000757///negative regulation of peptidyl-lysine acetylation+++GO:2000773///negative regulation of cellular senescence+++GO:2000774///positive regulation of cellular senescence" 93760 93760 'Arid1a' mRNA 2406 2388 2210 17.07 16.65 16.64 12.8 11.15 13.23 16.78666667 12.39333333 2081 1765 2080 2334.666667 1975.333333 0.001304781 -0.252936722 04714///Thermogenesis+++05225///Hepatocellular carcinoma GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016514///SWI/SNF complex+++GO:0035060///brahma complex+++GO:0070603///SWI/SNF superfamily-type complex+++GO:0071564///npBAF complex+++GO:0071565///nBAF complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0031491///nucleosome binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001704///formation of primary germ layer+++GO:0001843///neural tube closure+++GO:0003205///cardiac chamber development+++GO:0003408///optic cup formation involved in camera-type eye development+++GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0006338///chromatin remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007369///gastrulation+++GO:0007399///nervous system development+++GO:0007566///embryo implantation+++GO:0019827///stem cell population maintenance+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0030521///androgen receptor signaling pathway+++GO:0030900///forebrain development+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055007///cardiac muscle cell differentiation+++GO:0060674///placenta blood vessel development+++GO:0070829///heterochromatin maintenance+++GO:1901998///toxin transport" 93761 93761 'Smarca1' mRNA 729 739 726 8.75 8.73 9.27 5.21 5.22 4.95 8.916666667 5.126666667 503 501 462 731.3333333 488.6666667 3.91E-08 -0.5939499 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016589///NURF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0090537///CERF complex "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008134///transcription factor binding+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0031491///nucleosome binding+++GO:0036310///annealing helicase activity+++GO:0070615///nucleosome-dependent ATPase activity" "GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000177///regulation of neural precursor cell proliferation" 93762 93762 'Smarca5' mRNA 908 934 647 10.49 10.61 7.93 9.12 7.32 8.7 9.676666667 8.38 909 713 840 829.6666667 820.6666667 0.890748935 -0.022213661 GO:0000793///condensed chromosome+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005677///chromatin silencing complex+++GO:0005829///cytosol+++GO:0016589///NURF complex+++GO:0031010///ISWI-type complex+++GO:0031213///RSF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043596///nuclear replication fork "GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0016887///ATPase activity+++GO:0031491///nucleosome binding+++GO:0042393///histone binding+++GO:0070615///nucleosome-dependent ATPase activity" "GO:0000183///chromatin silencing at rDNA+++GO:0006325///chromatin organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0006352///DNA-templated transcription, initiation+++GO:0009790///embryo development+++GO:0016584///nucleosome positioning+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor" 93765 93765 'Ube2n' mRNA 2590 2617 2444 66.42 67.56 67.42 94.04 99.9 94.04 67.13333333 95.99333333 3742 3855 3581 2550.333333 3726 2.32E-17 0.536185021 04120///Ubiquitin mediated proteolysis+++04624///Toll and Imd signaling pathway+++05131///Shigellosis GO:0000151///ubiquitin ligase complex+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031372///UBC13-MMS2 complex+++GO:0032991///protein-containing complex+++GO:0035370///UBC13-UEV1A complex GO:0000166///nucleotide binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0043130///ubiquitin binding+++GO:0061631///ubiquitin conjugating enzyme activity GO:0000209///protein polyubiquitination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000729///DNA double-strand break processing+++GO:0006281///DNA repair+++GO:0006301///postreplication repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0016574///histone ubiquitination+++GO:0031058///positive regulation of histone modification+++GO:0033182///regulation of histone ubiquitination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045739///positive regulation of DNA repair+++GO:0050852///T cell receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0070534///protein K63-linked ubiquitination 93790 93790 'Nipa2' mRNA 726.36 630.47 657.77 10.99 9.51 10.9 18.48 18.93 19.12 10.46666667 18.84333333 1334.89 1350.3 1345.86 671.5333333 1343.683333 1.24E-26 0.989247286 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005515///protein binding+++GO:0015095///magnesium ion transmembrane transporter activity GO:0006811///ion transport+++GO:0015693///magnesium ion transport+++GO:1903830///magnesium ion transmembrane transport 93834 93834 'Peli2' mRNA 1823 2037 961 21.6 22.74 9.7 4.35 6.92 6.72 18.01333333 5.996666667 552 796 780 1607 709.3333333 0.001218625 -1.171759702 GO:0005829///cytosol+++GO:0016020///membrane "GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030674///protein binding, bridging+++GO:0061630///ubiquitin protein ligase activity" GO:0000209///protein polyubiquitination+++GO:0001934///positive regulation of protein phosphorylation+++GO:0008063///Toll signaling pathway+++GO:0008592///regulation of Toll signaling pathway+++GO:0016567///protein ubiquitination+++GO:0043410///positive regulation of MAPK cascade 93835 93835 'Amn' mRNA 4 1 2 0.17 0.04 0.09 0.07 0.04 0.15 0.1 0.086666667 2 1 5 2.333333333 2.666666667 0.930263498 0.180954913 GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0030139///endocytic vesicle+++GO:0031526///brush border membrane+++GO:0032991///protein-containing complex+++GO:0045177///apical part of cell GO:0005102///signaling receptor binding+++GO:0038024///cargo receptor activity GO:0006898///receptor-mediated endocytosis+++GO:0007275///multicellular organism development+++GO:0007588///excretion+++GO:0008104///protein localization+++GO:0009235///cobalamin metabolic process+++GO:0015031///protein transport+++GO:0015889///cobalamin transport+++GO:0043001///Golgi to plasma membrane protein transport 93836 93836 'Rnf111' mRNA 1301 1303 643 14.4 14.01 7.5 7.04 9.11 9.65 11.97 8.6 733 938 980 1082.333333 883.6666667 0.484255207 -0.285964243 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0032991///protein-containing complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0032184///SUMO polymer binding+++GO:0046332///SMAD binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007275///multicellular organism development+++GO:0007389///pattern specification process+++GO:0016567///protein ubiquitination+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0045893///positive regulation of transcription, DNA-templated" 93837 93837 'Dach2' mRNA 355 351 303 5.72 5.7 5.5 4.65 4.33 4.92 5.64 4.633333333 329 283 328 336.3333333 313.3333333 0.525641655 -0.11236586 GO:0005634///nucleus+++GO:0005667///transcription factor complex "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding" GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0046545///development of primary female sexual characteristics 93838 93838 'Dqx1' mRNA 121.71 149.3 127.86 2.23 2.68 2.49 1.22 1.01 0.78 2.466666667 1.003333333 75.08 61.94 45.24 132.9566667 60.75333333 2.68E-05 -1.145871065 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex GO:0000166///nucleotide binding+++GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity GO:0032508///DNA duplex unwinding 93840 93840 'Vangl2' mRNA 1158 1167 1121 10.8 10.65 11.06 4.74 5 5.09 10.83666667 4.943333333 587 606 611 1148.666667 601.3333333 5.32E-25 -0.945022111 04310///Wnt signaling pathway GO:0001725///stress fiber+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0060187///cell pole+++GO:0071944///cell periphery+++GO:0090651///apical cytoplasm GO:0005515///protein binding "GO:0001569///branching involved in blood vessel morphogenesis+++GO:0001736///establishment of planar polarity+++GO:0001843///neural tube closure+++GO:0001942///hair follicle development+++GO:0001947///heart looping+++GO:0003148///outflow tract septum morphogenesis+++GO:0003149///membranous septum morphogenesis+++GO:0003150///muscular septum morphogenesis+++GO:0003347///epicardial cell to mesenchymal cell transition+++GO:0003402///planar cell polarity pathway involved in axis elongation+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0022007///convergent extension involved in neural plate elongation+++GO:0030111///regulation of Wnt signaling pathway+++GO:0032835///glomerulus development+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0035019///somatic stem cell population maintenance+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0035787///cell migration involved in kidney development+++GO:0036342///post-anal tail morphogenesis+++GO:0036514///dopaminergic neuron axon guidance+++GO:0036515///serotonergic neuron axon guidance+++GO:0042060///wound healing+++GO:0043507///positive regulation of JUN kinase activity+++GO:0045176///apical protein localization+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0048103///somatic stem cell division+++GO:0048105///establishment of body hair planar orientation+++GO:0048546///digestive tract morphogenesis+++GO:0060028///convergent extension involved in axis elongation+++GO:0060029///convergent extension involved in organogenesis+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060119///inner ear receptor cell development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060488///orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis+++GO:0060489///planar dichotomous subdivision of terminal units involved in lung branching morphogenesis+++GO:0060490///lateral sprouting involved in lung morphogenesis+++GO:0060947///cardiac vascular smooth muscle cell differentiation+++GO:0060993///kidney morphogenesis+++GO:0061346///planar cell polarity pathway involved in heart morphogenesis+++GO:0090102///cochlea development+++GO:0090103///cochlea morphogenesis+++GO:0090162///establishment of epithelial cell polarity+++GO:0090175///regulation of establishment of planar polarity+++GO:0090177///establishment of planar polarity involved in neural tube closure+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:1904938///planar cell polarity pathway involved in axon guidance+++GO:1905515///non-motile cilium assembly" 93841 93841 'Uchl4' mRNA 122.19 114.18 136.06 6.5 6 7.68 4.37 3.75 3.53 6.726666667 3.883333333 94.19 78.84 73.52 124.1433333 82.18333333 0.018668147 -0.619897948 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0043130///ubiquitin binding GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0030163///protein catabolic process 93842 93842 'Igsf9' mRNA 1096 1079 943 14.05 13.66 12.89 6.35 5.25 5.31 13.53333333 5.636666667 567 462 464 1039.333333 497.6666667 5.39E-25 -1.073475638 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0045202///synapse+++GO:0060077///inhibitory synapse GO:0098632///cell-cell adhesion mediator activity GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0016358///dendrite development+++GO:0030154///cell differentiation+++GO:0050807///regulation of synapse organization+++GO:0098609///cell-cell adhesion 93843 93843 'Pnck' mRNA 479 483 464 19.07 18.86 19.57 4.27 5.28 4.87 19.16666667 4.806666667 126 147 136 475.3333333 136.3333333 1.02E-33 -1.81250894 GO:0005622///intracellular+++GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0005516///calmodulin binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation 93871 93871 'Brwd1' mRNA 1786 1827 1719 19.57 19.67 18.75 15.27 15.72 16.75 19.33 15.91333333 1438 1359 1427 1777.333333 1408 2.49E-06 -0.347689023 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0005515///protein binding GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0008360///regulation of cell shape 93872 93872 'Pcdhb1' mRNA 45 41 36 1.02 0.92 0.87 0.1 0.18 0.04 0.936666667 0.106666667 5 9 2 40.66666667 5.333333333 1.84E-06 -2.937353943 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93873 93873 'Pcdhb2' mRNA 6 9 16 0.12 0.18 0.34 0.05 0.05 0.04 0.213333333 0.046666667 3 3 2 10.33333333 2.666666667 0.071537746 -1.984680611 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93874 93874 'Pcdhb3' mRNA 40 26 62 0.57 0.37 0.94 0.01 0.13 0.05 0.626666667 0.063333333 1 10 4 42.66666667 5 5.40E-06 -3.114571083 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93875 93875 'Pcdhb4' mRNA 16.82 25.03 15.98 0.25 0.36 0.25 0.1 0.06 0.01 0.286666667 0.056666667 8 5 1 19.27666667 4.666666667 0.017526447 -2.00977975 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93876 93876 'Pcdhb5' mRNA 16 23.99 16.13 0.25 0.36 0.26 0 0.11 0.03 0.29 0.046666667 0 8 2 18.70666667 3.333333333 0.009912458 -2.453561866 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93877 93877 'Pcdhb6' mRNA 81.02 67.64 61.03 1.23 1.01 0.98 0.13 0.01 0.1 1.073333333 0.08 10 1 7 69.89666667 6 1.78E-11 -3.551749758 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009988///cell-cell recognition 93878 93878 'Pcdhb7' mRNA 85.01 103 105.87 1.32 1.57 1.74 0.05 0.12 0.19 1.543333333 0.12 4 9 14 97.96 9 1.85E-15 -3.451631358 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93879 93879 'Pcdhb8' mRNA 23.98 21.36 42.99 0.57 0.5 1.09 0.02 0.04 0.02 0.72 0.026666667 1 2 1 29.44333333 1.333333333 4.73E-06 -4.454057426 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93880 93880 'Pcdhb9' mRNA 57 67.01 70 1.02 1.18 1.33 0.09 0.18 0.24 1.176666667 0.17 6 11 15 64.67 10.66666667 1.58E-08 -2.611791177 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93881 93881 'Pcdhb10' mRNA 28 62 27 0.54 1.18 0.56 0.03 0 0 0.76 0.01 2 0 0 39 0.666666667 1.24E-06 -5.87326328 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93882 93882 'Pcdhb11' mRNA 140.01 106.23 130.57 2.1 1.57 2.08 0.14 0.2 0.08 1.916666667 0.14 11 15 6 125.6033333 10.66666667 3.80E-20 -3.568653832 GO:0005887///integral component of plasma membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93883 93883 'Pcdhb12' mRNA 62.06 67.77 57.43 1.12 1.21 1.1 0.17 0.11 0.16 1.143333333 0.146666667 11 7 10 62.42 9.333333333 2.79E-09 -2.743138158 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93884 93884 'Pcdhb13' mRNA 54 53 35 0.79 0.77 0.55 0 0.08 0.03 0.703333333 0.036666667 0 6 2 47.33333333 2.666666667 8.38E-09 -4.146884202 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93885 93885 'Pcdhb14' mRNA 156 180.97 156 2.47 2.82 2.62 0.44 0.25 0.4 2.636666667 0.363333333 32 18 28 164.3233333 26 1.48E-20 -2.670017086 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93886 93886 'Pcdhb15' mRNA 31 39 29 0.61 0.76 0.61 0.05 0.04 0.09 0.66 0.06 3 2 5 33 3.333333333 3.01E-06 -3.315516047 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93887 93887 'Pcdhb16' mRNA 182 200 202 1.84 1.99 2.17 0.16 0.22 0.1 2 0.16 18 24 11 194.6666667 17.66666667 3.82E-30 -3.474859948 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097381///photoreceptor disc membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007268///chemical synaptic transmission+++GO:0007416///synapse assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 93888 93888 'Pcdhb17' mRNA 342 364 287 5.71 5.98 5.08 0.54 0.51 0.69 5.59 0.58 37 34 46 331 39 1.47E-46 -3.093063553 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0097381///photoreceptor disc membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007268///chemical synaptic transmission+++GO:0007416///synapse assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 93889 93889 'Pcdhb18' mRNA 129.12 114 101 1.37 1.19 1.14 0.09 0.06 0.09 1.233333333 0.08 10 6 9 114.7066667 8.333333333 1.47E-20 -3.792678731 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93890 93890 'Pcdhb19' mRNA 54 49 55 0.61 0.55 0.66 0.07 0.11 0.16 0.606666667 0.113333333 7 11 16 52.66666667 11.33333333 3.85E-06 -2.227898777 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93891 93891 'Pcdhb20' mRNA 157 158 181 2.52 2.49 3.08 0.39 0.21 0.2 2.696666667 0.266666667 28 15 14 165.3333333 19 4.23E-23 -3.140778446 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93892 93892 'Pcdhb21' mRNA 111 94 81 2.27 1.89 1.75 0.16 0.04 0.26 1.97 0.153333333 9 2 14 95.33333333 8.333333333 1.13E-14 -3.526177318 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93893 93893 'Pcdhb22' mRNA 102 81 96 1.82 1.43 1.82 0.2 0.24 0.26 1.69 0.233333333 13 15 16 93 14.66666667 1.03E-12 -2.678246414 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032391///photoreceptor connecting cilium GO:0003674///molecular_function+++GO:0005509///calcium ion binding GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules 93896 93896 'Glp2r' mRNA 1 1 0 0.01 0.03 0 0 0 0.03 0.013333333 0.01 0 0 1 0.666666667 0.333333333 0.863090843 -0.875225752 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004967///glucagon receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0071377///cellular response to glucagon stimulus 93897 93897 'Fzd10' mRNA 58 82 65 1.07 1.48 1.27 1.5 1.23 1.25 1.273333333 1.326666667 94 75 76 68.33333333 81.66666667 0.4891992 0.245352328 04150///mTOR signaling pathway+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++04934///Cushing syndrome+++05010///Alzheimer disease+++05022///Pathways of neurodegeneration - multiple diseases+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05217///Basal cell carcinoma+++05224///Breast cancer+++05225///Hepatocellular carcinoma+++05226///Gastric cancer GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0042813///Wnt-activated receptor activity GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0034260///negative regulation of GTPase activity+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0060070///canonical Wnt signaling pathway 93898 93898 'Cers1' mRNA 422.74 426.39 372.32 8.59 8.52 8.02 2.29 3.02 2.79 8.376666667 2.7 129.99 167.02 152.82 407.15 149.9433333 1.24E-19 -1.453042038 00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005515///protein binding+++GO:0008083///growth factor activity+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0007420///brain development+++GO:0030148///sphingolipid biosynthetic process+++GO:0035690///cellular response to drug+++GO:0036146///cellular response to mycotoxin+++GO:0046325///negative regulation of glucose import+++GO:0046513///ceramide biosynthetic process+++GO:0051974///negative regulation of telomerase activity+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071492///cellular response to UV-A+++GO:0072721///cellular response to dithiothreitol+++GO:1901526///positive regulation of mitophagy 93960 93960 'Nkd1' mRNA 2252 2181 1739 39.78 38.16 32.61 14.12 20.53 19.61 36.85 18.08666667 931 1237 1187 2057.333333 1118.333333 2.15E-15 -0.883444749 04310///Wnt signaling pathway+++04390///Hippo signaling pathway GO:0000159///protein phosphatase type 2A complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding "GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016055///Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045732///positive regulation of protein catabolic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1901231///positive regulation of non-canonical Wnt signaling pathway via JNK cascade+++GO:1901233///negative regulation of convergent extension involved in axis elongation+++GO:2000096///positive regulation of Wnt signaling pathway, planar cell polarity pathway" 93961 93961 'B3galt5' mRNA 455 469 418 4.62 4.64 4.53 1.76 1.51 1.6 4.596666667 1.623333333 189 158 168 447.3333333 171.6666667 4.18E-22 -1.393111016 00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0009617///response to bacterium+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 94040 94040 'Clmn' mRNA 1330.29 1299.01 1141.01 5.84 5.61 5.31 4.48 3.72 3.94 5.586666667 4.046666667 1175.81 954.07 1001.87 1256.77 1043.916667 0.003687308 -0.279610621 GO:0005640///nuclear outer membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex GO:0003779///actin binding+++GO:0051015///actin filament binding GO:0007097///nuclear migration+++GO:0008285///negative regulation of cell proliferation+++GO:0031175///neuron projection development 94043 94043 'Tm2d1' mRNA 1176 1130 1098 76.84 73.23 75.81 59.88 63.19 56.73 75.29333333 59.93333333 1049 1077 960 1134.666667 1028.666667 0.122504907 -0.152869575 GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0001540///amyloid-beta binding+++GO:0004930///G protein-coupled receptor activity GO:0006915///apoptotic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097190///apoptotic signaling pathway 94044 94044 'Bcl2l13' mRNA 697 702 635 5.31 5.26 5.14 5.25 5.13 5.55 5.236666667 5.31 793 756 811 678 786.6666667 0.052135827 0.203953651 04137///Mitophagy - animal+++05134///Legionellosis GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0003674///molecular_function GO:0006915///apoptotic process+++GO:0042981///regulation of apoptotic process 94045 94045 'P2rx5' mRNA 56 53 48 1.28 1.18 1.17 1.78 2.61 2.17 1.21 2.186666667 89 127 106 52.33333333 107.3333333 4.67E-04 1.029332449 04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005639///integral component of nuclear inner membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse GO:0000166///nucleotide binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0007166///cell surface receptor signaling pathway+++GO:0009268///response to pH+++GO:0010043///response to zinc ion+++GO:0033198///response to ATP+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0043416///regulation of skeletal muscle tissue regeneration+++GO:0051592///response to calcium ion+++GO:0060079///excitatory postsynaptic potential+++GO:0098655///cation transmembrane transport+++GO:1905665///positive regulation of calcium ion import across plasma membrane 94047 94047 'Tmem121b' mRNA 1 0 0 0.01 0 0 0 0.02 0.01 0.003333333 0.01 0 2 1 0.333333333 1 0.727961753 1.486177199 94061 94061 'Mrpl1' mRNA 329 333.04 344.67 9.3 9.39 10.16 10.94 10.97 11.74 9.616666667 11.21666667 379.17 389 392.71 335.57 386.96 0.209115748 0.192760963 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome GO:0000470///maturation of LSU-rRNA+++GO:0006412///translation 94062 94062 'Mrpl3' mRNA 725 732 705 26.43 25.55 27.39 27.59 27.91 27 26.45666667 27.5 871 847 823 720.6666667 847 0.029186546 0.221181856 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 94063 94063 'Mrpl16' mRNA 277 284 285 15.18 15.37 16.57 19.24 21.11 20.3 15.70666667 20.21666667 403 431 411 282 415 1.01E-04 0.54554459 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding GO:0006412///translation+++GO:0032543///mitochondrial translation 94064 94064 'Mrpl27' mRNA 1482.87 1478.69 1496.85 129.24 128.03 137.5 132.1 150.13 135.7 131.59 139.31 1635.11 1783.07 1610.1 1486.136667 1676.093333 0.077724607 0.162220104 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 94065 94065 'Mrpl34' mRNA 447 383 399 51.12 43.56 48.44 53.88 64.37 62.84 47.70666667 60.36333333 538 625 605 409.6666667 589.3333333 8.73E-05 0.514124073 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation 94066 94066 'Mrpl36' mRNA 532 546 596 38.74 39.36 46.06 59.88 63.02 62.97 41.38666667 61.95666667 942 966 957 558 955 1.07E-12 0.761135301 03010///Ribosome GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome+++GO:0016604///nuclear body GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0042254///ribosome biogenesis 94067 94067 'Mrpl43' mRNA 950.48 998.67 906.77 48.02 49.83 48.61 56.52 54.95 55.96 48.82 55.81 1283.89 1217.24 1229.11 951.9733333 1243.413333 7.46E-06 0.374733574 GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome GO:0003735///structural constituent of ribosome GO:0006412///translation+++GO:0032543///mitochondrial translation 94088 94088 'Trim6' mRNA 12 11 11 0.17 0.19 0.2 0.28 0.51 0.77 0.186666667 0.52 23 33 47 11.33333333 34.33333333 0.005091752 1.591335316 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:1990782///protein tyrosine kinase binding" "GO:0000209///protein polyubiquitination+++GO:0002230///positive regulation of defense response to virus by host+++GO:0002720///positive regulation of cytokine production involved in immune response+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0010994///free ubiquitin chain polymerization+++GO:0016567///protein ubiquitination+++GO:0031647///regulation of protein stability+++GO:0032496///response to lipopolysaccharide+++GO:0032880///regulation of protein localization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035458///cellular response to interferon-beta+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0098586///cellular response to virus+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:2000737///negative regulation of stem cell differentiation" 94089 94089 'Trim7' mRNA 218 214.02 204 4.38 4.13 4.99 4.62 4.44 4.11 4.5 4.39 258 233 228.04 212.0066667 239.68 0.399384112 0.164919498 GO:0005634///nucleus+++GO:0005737///cytoplasm GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016567///protein ubiquitination 94090 94090 'Trim9' mRNA 809.18 923.02 808.96 5.47 6.6 6.43 0.58 0.39 0.38 6.166666667 0.45 189.93 135.89 163.84 847.0533333 163.22 1.01E-72 -2.395351741 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0099523///presynaptic cytosol GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0016079///synaptic vesicle exocytosis+++GO:0016567///protein ubiquitination+++GO:0035544///negative regulation of SNARE complex assembly+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045955///negative regulation of calcium ion-dependent exocytosis 94091 94091 'Trim11' mRNA 901 882 849 21.81 22.41 22.87 20.57 22.17 20.06 22.36333333 20.93333333 883 901 811 877.3333333 865 0.81493066 -0.031764841 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity "GO:0010468///regulation of gene expression+++GO:0016567///protein ubiquitination+++GO:0032897///negative regulation of viral transcription+++GO:0044790///negative regulation by host of viral release from host cell+++GO:0045087///innate immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046597///negative regulation of viral entry into host cell+++GO:0046598///positive regulation of viral entry into host cell+++GO:0050768///negative regulation of neurogenesis+++GO:0051607///defense response to virus+++GO:1902187///negative regulation of viral release from host cell" 94092 94092 'Trim16' mRNA 746 719 759 10.37 9.83 11.19 3.93 4.69 4.9 10.46333333 4.506666667 326 380 393 741.3333333 366.3333333 8.18E-17 -1.029043734 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016605///PML body GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0019966///interleukin-1 binding+++GO:0032089///NACHT domain binding+++GO:0046872///metal ion binding "GO:0032526///response to retinoic acid+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0043966///histone H3 acetylation+++GO:0043967///histone H4 acetylation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046683///response to organophosphorus+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0060416///response to growth hormone" 94093 94093 'Trim33' mRNA 521 533 495 3.09 3.11 3.12 2.4 2.26 2.49 3.106666667 2.383333333 466 428 467 516.3333333 453.6666667 0.12152172 -0.198131253 GO:0005634///nucleus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0070410///co-SMAD binding+++GO:0070412///R-SMAD binding GO:0016567///protein ubiquitination+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway 94094 94094 'Trim34a' mRNA 348.8 334.03 344.68 7.48 7.06 7.9 8.55 8.29 8.4 7.48 8.413333333 457.21 433.53 436.2 342.5033333 442.3133333 0.008027656 0.357110414 GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0010468///regulation of gene expression+++GO:0010508///positive regulation of autophagy+++GO:0016567///protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0045087///innate immune response+++GO:0046596///regulation of viral entry into host cell+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051607///defense response to virus 94109 94109 'Csmd1' mRNA 232 223 216 0.89 0.87 0.86 0.11 0.07 0.1 0.873333333 0.093333333 30 19 26 223.6666667 25 7.05E-34 -3.174594927 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001964///startle response+++GO:0007613///memory+++GO:0008584///male gonad development+++GO:0008585///female gonad development+++GO:0035846///oviduct epithelium development+++GO:0042593///glucose homeostasis+++GO:0060745///mammary gland branching involved in pregnancy+++GO:1990708///conditioned place preference 94111 94111 'Mepe' mRNA 27 23 18 0.93 0.78 0.66 1.26 0.62 0.5 0.79 0.793333333 42 20 16 22.66666667 26 0.807780118 0.183652452 GO:0005576///extracellular region+++GO:0031012///extracellular matrix GO:1990430///extracellular matrix protein binding GO:0001501///skeletal system development+++GO:0030502///negative regulation of bone mineralization+++GO:0031214///biomineral tissue development 94112 94112 'Med15' mRNA 1138.09 1210.04 1083.06 18.65 19.64 18.73 23.95 22.08 21.58 19.00666667 22.53666667 1682.05 1519.97 1474 1143.73 1558.673333 9.18E-08 0.43488545 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016592///mediator complex GO:0003712///transcription coregulator activity "GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance" 94175 94175 'Hrg' mRNA 4 0 0 0.13 0 0 0 0 0 0.043333333 0 0 0 0 1.333333333 0 0.535994789 -2.842745962 GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0031982///vesicle+++GO:0036019///endolysosome+++GO:0061474///phagolysosome membrane+++GO:0062023///collagen-containing extracellular matrix GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0008270///zinc ion binding+++GO:0019865///immunoglobulin binding+++GO:0020037///heme binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0046872///metal ion binding GO:0001525///angiogenesis+++GO:0002839///positive regulation of immune response to tumor cell+++GO:0006935///chemotaxis+++GO:0007162///negative regulation of cell adhesion+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0008285///negative regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0010543///regulation of platelet activation+++GO:0010593///negative regulation of lamellipodium assembly+++GO:0010951///negative regulation of endopeptidase activity+++GO:0014070///response to organic cyclic compound+++GO:0015886///heme transport+++GO:0016525///negative regulation of angiogenesis+++GO:0030168///platelet activation+++GO:0030193///regulation of blood coagulation+++GO:0030308///negative regulation of cell growth+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0034395///regulation of transcription from RNA polymerase II promoter in response to iron+++GO:0042730///fibrinolysis+++GO:0043065///positive regulation of apoptotic process+++GO:0043254///regulation of protein complex assembly+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0050832///defense response to fungus+++GO:0051838///cytolysis by host of symbiont cells+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051918///negative regulation of fibrinolysis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0097037///heme export+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:2000504///positive regulation of blood vessel remodeling+++GO:2001027///negative regulation of endothelial cell chemotaxis 94176 94176 'Dock2' mRNA 45 68 103 0.43 0.56 0.9 7.5 6.68 7.22 0.63 7.133333333 1027 883 948 72 952.6666667 3.81E-25 3.698010373 04062///Chemokine signaling pathway GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0042608///T cell receptor binding GO:0001766///membrane raft polarization+++GO:0001768///establishment of T cell polarity+++GO:0001771///immunological synapse formation+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0006935///chemotaxis+++GO:0007010///cytoskeleton organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0042098///T cell proliferation+++GO:0042110///T cell activation+++GO:0044351///macropinocytosis+++GO:0045059///positive thymic T cell selection+++GO:0045060///negative thymic T cell selection+++GO:0046631///alpha-beta T cell activation+++GO:0046633///alpha-beta T cell proliferation+++GO:0050766///positive regulation of phagocytosis+++GO:0050790///regulation of catalytic activity 94178 94178 'Mcoln1' mRNA 1365 1449 1295 38.79 40.57 39.04 38.64 36.69 37.01 39.46666667 37.44666667 1563 1449 1449 1369.666667 1487 0.216529317 0.107517733 04020///Calcium signaling pathway+++04142///Lysosome GO:0001891///phagocytic cup+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031902///late endosome membrane+++GO:0042995///cell projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043235///receptor complex+++GO:0097708///intracellular vesicle "GO:0005261///cation channel activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0072345///NAADP-sensitive calcium-release channel activity+++GO:0097682///intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity+++GO:0099604///ligand-gated calcium channel activity" GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0016197///endosomal transport+++GO:0019722///calcium-mediated signaling+++GO:0034220///ion transmembrane transport+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0051289///protein homotetramerization+++GO:0070588///calcium ion transmembrane transport+++GO:0071277///cellular response to calcium ion+++GO:0071467///cellular response to pH+++GO:0090382///phagosome maturation+++GO:0097352///autophagosome maturation+++GO:0098655///cation transmembrane transport 94179 94179 'Krt23' mRNA 418 416 417 15.87 15.58 16.8 14.61 15.34 15 16.08333333 14.98333333 442 453 439 417 444.6666667 0.614313191 0.080588388 04915///Estrogen signaling pathway+++05150///Staphylococcus aureus infection GO:0005882///intermediate filament GO:0005198///structural molecule activity GO:0008150///biological_process 94180 94180 'Acsbg1' mRNA 55 59 61 1.05 1.09 1.23 1.09 0.87 0.64 1.123333333 0.866666667 65 51 37 58.33333333 51 0.638969398 -0.210242554 00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++01212///Fatty acid metabolism+++03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle GO:0000166///nucleotide binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016405///CoA-ligase activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity GO:0000038///very long-chain fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0051384///response to glucocorticoid 94181 94181 'Nans' mRNA 442 462 374 13.21 13.61 11.86 25.65 24.2 24.33 12.89333333 24.72666667 985 908 904 426 932.3333333 1.59E-27 1.120756 00520///Amino sugar and nucleotide sugar metabolism+++01250///Biosynthesis of nucleotide sugars GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0047444///N-acylneuraminate-9-phosphate synthase activity GO:0016051///carbohydrate biosynthetic process+++GO:0070085///glycosylation 94184 94184 'Pdxdc1' mRNA 2832.01 3017.88 2981.84 41.92 44.07 47.21 38.21 36.1 35 44.4 36.43666667 2948.43 2728 2607.77 2943.91 2761.4 0.196288359 -0.105953825 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle GO:0003824///catalytic activity+++GO:0008117///sphinganine-1-phosphate aldolase activity+++GO:0016829///lyase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0030170///pyridoxal phosphate binding GO:0001667///ameboidal-type cell migration+++GO:0019752///carboxylic acid metabolic process+++GO:0030149///sphingolipid catabolic process 94185 94185 'Tnfrsf21' mRNA 4975 5091 4927 74.46 74.96 78.22 53.18 54.08 53.11 75.88 53.45666667 4089 4062 3955 4997.666667 4035.333333 4.88E-08 -0.320620594 04060///Cytokine-cytokine receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0031226///intrinsic component of plasma membrane GO:0001783///B cell apoptotic process+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006959///humoral immune response+++GO:0007165///signal transduction+++GO:0007413///axonal fasciculation+++GO:0030889///negative regulation of B cell proliferation+++GO:0031642///negative regulation of myelination+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032696///negative regulation of interleukin-13 production+++GO:0032714///negative regulation of interleukin-5 production+++GO:0042130///negative regulation of T cell proliferation+++GO:0042552///myelination+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0050852///T cell receptor signaling pathway+++GO:0051402///neuron apoptotic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0097252///oligodendrocyte apoptotic process 94186 94186 'Strn3' mRNA 1157.99 1191.65 1165.56 13.04 12.26 13.97 13.46 11.2 13.95 13.09 12.87 1281.42 1059.12 1295.56 1171.733333 1212.033333 0.787130696 0.035718082 04013///MAPK signaling pathway - fly GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0090443///FAR/SIN/STRIPAK complex GO:0005516///calmodulin binding+++GO:0031267///small GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070016///armadillo repeat domain binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II" 94187 94187 'Zfp423' mRNA 1012 981 822 11.5 10.94 10.46 4.35 4.4 3.85 10.96666667 4.2 424 432 367 938.3333333 407.6666667 6.25E-28 -1.211048795 GO:0005634///nucleus+++GO:0005654///nucleoplasm "GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0046872///metal ion binding" "GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021930///cerebellar granule cell precursor proliferation+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0030154///cell differentiation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:0120163///negative regulation of cold-induced thermogenesis" 94190 94190 'Ophn1' mRNA 521 514 503.2 5.92 5.6 6.16 6.95 7.52 7.64 5.893333333 7.37 761 761 751 512.7333333 757.6666667 1.21E-07 0.551885352 GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse GO:0003779///actin binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0035255///ionotropic glutamate receptor binding "GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0021707///cerebellar granule cell differentiation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0030036///actin cytoskeleton organization+++GO:0030100///regulation of endocytosis+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:0034329///cell junction assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0048488///synaptic vesicle endocytosis+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0050790///regulation of catalytic activity+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0098880///maintenance of postsynaptic specialization structure+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:1901799///negative regulation of proteasomal protein catabolic process" 94191 94191 'Adarb2' mRNA 74.73 63.12 75.24 0.85 0.71 0.91 0.44 0.34 0.46 0.823333333 0.413333333 44.26 33.17 44.5 71.03 40.64333333 0.018670748 -0.825491464 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding GO:0006382///adenosine to inosine editing+++GO:0006396///RNA processing+++GO:0006397///mRNA processing 94192 94192 'C1galt1' mRNA 32 33 31 0.88 0.89 0.9 1.41 1.37 1.41 0.89 1.396666667 59 56 57 32 57.33333333 0.029361556 0.829797107 00512///Mucin type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008378///galactosyltransferase activity+++GO:0016263///glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding" "GO:0001525///angiogenesis+++GO:0001822///kidney development+++GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0007275///multicellular organism development+++GO:0016266///O-glycan processing+++GO:0016267///O-glycan processing, core 1+++GO:0030154///cell differentiation+++GO:0060576///intestinal epithelial cell development" 94212 94212 'Pag1' mRNA 901.64 964.21 814.53 2.17 2.32 2.09 2.39 1.91 2.37 2.193333333 2.223333333 1064.7 770.84 1017.01 893.46 950.85 0.596264475 0.078162999 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft GO:0005515///protein binding+++GO:0042169///SH2 domain binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0035556///intracellular signal transduction+++GO:0050863///regulation of T cell activation+++GO:0050868///negative regulation of T cell activation 94213 94213 'Ddx50' mRNA 1961 1814 1960 36.33 33.06 39.2 32.87 29.91 30.29 36.19666667 31.02333333 2029 1807 1807 1911.666667 1881 0.739272063 -0.038156419 GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005886///plasma membrane GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003724///RNA helicase activity+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity 94214 94214 'Spock2' mRNA 2481.94 2530 1475.19 28.76 28.61 18.2 10.57 9.5 10.41 25.19 10.16 1050 919 991 2162.376667 986.6666667 3.33E-07 -1.13271771 GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix GO:0005509///calcium ion binding+++GO:0005539///glycosaminoglycan binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0050840///extracellular matrix binding GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0030198///extracellular matrix organization+++GO:1990830///cellular response to leukemia inhibitory factor 94216 94216 'Col4a6' mRNA 54 48 49 0.44 0.38 0.42 0.73 0.57 0.5 0.413333333 0.6 105 81 70 50.33333333 85.33333333 0.020865366 0.74714001 04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++04512///ECM-receptor interaction+++04926///Relaxin signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04974///Protein digestion and absorption+++05146///Amoebiasis+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05222///Small cell lung cancer GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength GO:0030198///extracellular matrix organization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0071230///cellular response to amino acid stimulus 94217 94217 'Lrp1b' mRNA 11 9.98 7 0.04 0.05 0.04 0 0.04 0.03 0.043333333 0.023333333 1 8.01 8.18 9.326666667 5.73 0.583675133 -0.66295269 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0050750///low-density lipoprotein particle receptor binding GO:0001701///in utero embryonic development+++GO:0006897///endocytosis 94218 94218 'Cnnm3' mRNA 547.31 546.04 465.02 5.62 5.51 5.06 3.82 3.7 3.55 5.396666667 3.69 429 405 385 519.4566667 406.3333333 0.003625516 -0.363528217 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0006811///ion transport+++GO:0010960///magnesium ion homeostasis+++GO:0055085///transmembrane transport 94219 94219 'Cnnm2' mRNA 880.05 881.41 698.79 12.84 12.99 10.51 4.58 5.71 5.85 12.11333333 5.38 363.61 420.55 436.3 820.0833333 406.82 3.59E-17 -1.018248779 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0005524///ATP binding+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0006811///ion transport+++GO:0010960///magnesium ion homeostasis+++GO:0015693///magnesium ion transport+++GO:0055085///transmembrane transport+++GO:1903830///magnesium ion transmembrane transport 94220 94220 'Cnnm4' mRNA 623 697 761 7.29 8.02 9.45 8.93 8.46 9.74 8.253333333 9.043333333 878 813 928 693.6666667 873 0.010011821 0.31588511 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle GO:0015081///sodium ion transmembrane transporter activity+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006810///transport+++GO:0006811///ion transport+++GO:0007601///visual perception+++GO:0010960///magnesium ion homeostasis+++GO:0015693///magnesium ion transport+++GO:0031214///biomineral tissue development+++GO:0035725///sodium ion transmembrane transport+++GO:0050896///response to stimulus+++GO:0055065///metal ion homeostasis+++GO:0055085///transmembrane transport+++GO:0070166///enamel mineralization+++GO:1903830///magnesium ion transmembrane transport 94221 94221 'Gopc' mRNA 339 352 268 4.23 4.33 3.56 4.48 3.61 4.11 4.04 4.066666667 412 325 366 319.6666667 367.6666667 0.254054854 0.192892386 GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030140///trans-Golgi network transport vesicle+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0045202///synapse GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0019905///syntaxin binding+++GO:0030695///GTPase regulator activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0044325///ion channel binding GO:0006914///autophagy+++GO:0007289///spermatid nucleus differentiation+++GO:0010360///negative regulation of anion channel activity+++GO:0015031///protein transport+++GO:0043004///cytoplasmic sequestering of CFTR protein+++GO:0050790///regulation of catalytic activity+++GO:2000009///negative regulation of protein localization to cell surface 94222 94222 'Olig3' mRNA 70 83 16 1.92 2.25 0.47 0.1 0.07 0.07 1.546666667 0.08 4 3 3 56.33333333 3.333333333 1.38E-08 -4.06532877 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:1990837///sequence-specific double-stranded DNA binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0021522///spinal cord motor neuron differentiation+++GO:0030182///neuron differentiation+++GO:0097476///spinal cord motor neuron migration" 94223 94223 'Dgcr8' mRNA 496.23 528.08 520.09 5.82 6.25 6.53 4.96 3.99 4.5 6.2 4.483333333 487.38 377.08 436.03 514.8 433.4966667 0.058468179 -0.26272223 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0016604///nuclear body+++GO:0070877///microprocessor complex GO:0003723///RNA binding+++GO:0003725///double-stranded RNA binding+++GO:0020037///heme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0070878///primary miRNA binding GO:0031053///primary miRNA processing+++GO:0072091///regulation of stem cell proliferation 94224 94224 'Srd5a2' mRNA 4 8 6 0.06 0.12 0.1 0.2 0.17 0.26 0.093333333 0.21 15 13 19 6 15.66666667 0.095054072 1.373889832 00140///Steroid hormone biosynthesis+++05215///Prostate cancer GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070852///cell body fiber "GO:0003865///3-oxo-5-alpha-steroid 4-dehydrogenase activity+++GO:0009917///sterol 5-alpha reductase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0030283///testosterone dehydrogenase [NAD(P)] activity+++GO:0033218///amide binding+++GO:0047751///cholestenone 5-alpha-reductase activity" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006702///androgen biosynthetic process+++GO:0006706///steroid catabolic process+++GO:0007548///sex differentiation+++GO:0008202///steroid metabolic process+++GO:0008209///androgen metabolic process+++GO:0008584///male gonad development+++GO:0010033///response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0018879///biphenyl metabolic process+++GO:0018894///dibenzo-p-dioxin metabolic process+++GO:0018963///phthalate metabolic process+++GO:0021766///hippocampus development+++GO:0021854///hypothalamus development+++GO:0030154///cell differentiation+++GO:0030539///male genitalia development+++GO:0030540///female genitalia development+++GO:0031667///response to nutrient levels+++GO:0032354///response to follicle-stimulating hormone+++GO:0033574///response to testosterone+++GO:0042493///response to drug+++GO:0043434///response to peptide hormone+++GO:0048545///response to steroid hormone+++GO:0060348///bone development+++GO:0061370///testosterone biosynthetic process 94226 94226 'S1pr5' mRNA 2 8 9 0.04 0.18 0.21 0.45 0.42 0.34 0.143333333 0.403333333 23 21 17 6.333333333 20.33333333 0.031138533 1.661344312 04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0004930///G protein-coupled receptor activity+++GO:0038036///sphingosine-1-phosphate receptor activity GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019222///regulation of metabolic process+++GO:0045664///regulation of neuron differentiation 94227 94227 'Pi15' mRNA 55.29 44.44 41.87 0.42 0.33 0.34 0.22 0.1 0.19 0.363333333 0.17 33.79 14.7 27.13 47.2 25.20666667 0.045963406 -0.934138842 GO:0005576///extracellular region+++GO:0005615///extracellular space GO:0030414///peptidase inhibitor activity GO:0007275///multicellular organism development+++GO:0010466///negative regulation of peptidase activity 94229 94229 'Slc4a10' mRNA 4 15 9 0.04 0.15 0.09 0.04 0.07 0.09 0.093333333 0.066666667 5 8 10 9.333333333 7.666666667 0.8144279 -0.287817992 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0036477///somatodendritic compartment+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0043679///axon terminus+++GO:0045202///synapse+++GO:0097440///apical dendrite+++GO:0097441///basal dendrite+++GO:0097442///CA3 pyramidal cell dendrite+++GO:0098793///presynapse+++GO:0098794///postsynapse GO:0005452///inorganic anion exchanger activity+++GO:0008509///anion transmembrane transporter activity+++GO:0008510///sodium:bicarbonate symporter activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0022857///transmembrane transporter activity GO:0006486///protein glycosylation+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006820///anion transport+++GO:0006885///regulation of pH+++GO:0007601///visual perception+++GO:0009416///response to light stimulus+++GO:0009791///post-embryonic development+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0021860///pyramidal neuron development+++GO:0030641///regulation of cellular pH+++GO:0035264///multicellular organism growth+++GO:0035641///locomotory exploration behavior+++GO:0035725///sodium ion transmembrane transport+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0048854///brain morphogenesis+++GO:0050801///ion homeostasis+++GO:0051453///regulation of intracellular pH+++GO:0055085///transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902600///proton transmembrane transport 94230 94230 'Cpsf1' mRNA 1559 1554 1508 18.55 18.18 19.04 12.73 13.88 13.99 18.59 13.53333333 1232 1313 1311 1540.333333 1285.333333 0.001177517 -0.272199321 03015///mRNA surveillance pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0019899///enzyme binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding GO:0006378///mRNA polyadenylation+++GO:0006397///mRNA processing 94232 94232 'Ubqln4' mRNA 1346 1323 1069 21.79 21.08 18.33 11.71 11.84 12.41 20.4 11.98666667 832 822 855 1246 836.3333333 3.91E-10 -0.582695912 04141///Protein processing in endoplasmic reticulum+++05014///Amyotrophic lateral sclerosis GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0031595///nuclear proteasome complex+++GO:0031597///cytosolic proteasome complex+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0090734///site of DNA damage GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0036435///K48-linked polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1901097///negative regulation of autophagosome maturation+++GO:2000042///negative regulation of double-strand break repair via homologous recombination 94242 94242 'Tinagl1' mRNA 1083 1040 1078 31.64 29.93 33.38 73.36 67.77 67.53 31.65 69.55333333 2887 2605 2574 1067 2688.666667 9.26E-67 1.319539997 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix "GO:0004053///arginase activity+++GO:0005201///extracellular matrix structural constituent+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0016813///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines+++GO:0030145///manganese ion binding+++GO:0042802///identical protein binding+++GO:0043236///laminin binding+++GO:0046872///metal ion binding" GO:0000050///urea cycle+++GO:0001889///liver development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0006525///arginine metabolic process+++GO:0007565///female pregnancy+++GO:0007568///aging+++GO:0009611///response to wounding+++GO:0009635///response to herbicide+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0010269///response to selenium ion+++GO:0010963///regulation of L-arginine import+++GO:0014075///response to amine+++GO:0019547///arginine catabolic process to ornithine+++GO:0030324///lung development+++GO:0032496///response to lipopolysaccharide+++GO:0032964///collagen biosynthetic process+++GO:0033189///response to vitamin A+++GO:0033197///response to vitamin E+++GO:0042130///negative regulation of T cell proliferation+++GO:0042493///response to drug+++GO:0042832///defense response to protozoan+++GO:0043200///response to amino acid+++GO:0043434///response to peptide hormone+++GO:0045087///innate immune response+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0046686///response to cadmium ion+++GO:0048545///response to steroid hormone+++GO:0048678///response to axon injury+++GO:0051597///response to methylmercury+++GO:0060056///mammary gland involution+++GO:0060135///maternal process involved in female pregnancy+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0070301///cellular response to hydrogen peroxide+++GO:0070965///positive regulation of neutrophil mediated killing of fungus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071353///cellular response to interleukin-4+++GO:0071377///cellular response to glucagon stimulus+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2000552///negative regulation of T-helper 2 cell cytokine production 94244 94244 'Fkbp6' mRNA 2 3 4 0.09 0.13 0.19 0.04 0 0.23 0.136666667 0.09 1 0 6 3 2.333333333 0.863090843 -0.383460238 GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0042802///identical protein binding+++GO:0051879///Hsp90 protein binding GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0045070///positive regulation of viral genome replication+++GO:0051321///meiotic cell cycle 94245 94245 'Dtnbp1' mRNA 231.33 227.19 166.73 7.35 7.87 6.14 13.87 15.48 16.82 7.12 15.39 436.26 457.23 505.87 208.4166667 466.4533333 2.35E-14 1.158180764 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0014069///postsynaptic density+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0016528///sarcoplasm+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0030426///growth cone+++GO:0030496///midbody+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031083///BLOC-1 complex+++GO:0031410///cytoplasmic vesicle+++GO:0032279///asymmetric synapse+++GO:0033162///melanosome membrane+++GO:0042383///sarcolemma+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098978///glutamatergic synapse+++GO:1904115///axon cytoplasm GO:0005515///protein binding GO:0001822///kidney development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0002092///positive regulation of receptor internalization+++GO:0006469///negative regulation of protein kinase activity+++GO:0006996///organelle organization+++GO:0007517///muscle organ development+++GO:0007596///blood coagulation+++GO:0007613///memory+++GO:0008089///anterograde axonal transport+++GO:0010467///gene expression+++GO:0010628///positive regulation of gene expression+++GO:0014059///regulation of dopamine secretion+++GO:0031175///neuron projection development+++GO:0031532///actin cytoskeleton reorganization+++GO:0032091///negative regulation of protein binding+++GO:0043506///regulation of JUN kinase activity+++GO:0048490///anterograde synaptic vesicle transport+++GO:0048812///neuron projection morphogenesis+++GO:0048813///dendrite morphogenesis+++GO:0050896///response to stimulus+++GO:0060155///platelet dense granule organization+++GO:0060159///regulation of dopamine receptor signaling pathway+++GO:0060271///cilium assembly+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0061646///positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1901215///negative regulation of neuron death+++GO:1903441///protein localization to ciliary membrane+++GO:2000300///regulation of synaptic vesicle exocytosis 94246 94246 'Arid4b' mRNA 1797 1795 1592 16.19 15.94 15.28 13.19 12.12 12.43 15.80333333 12.58 1682 1507 1542 1728 1577 0.077503211 -0.142617906 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding "GO:0006325///chromatin organization+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0034773///histone H4-K20 trimethylation+++GO:0036124///histone H3-K9 trimethylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097368///establishment of Sertoli cell barrier" 94249 94249 'Slc24a3' mRNA 221 160 160 3.27 2.31 2.52 0.34 0.5 0.36 2.7 0.4 27 38 27 180.3333333 30.66666667 6.29E-20 -2.563903512 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery "GO:0005262///calcium channel activity+++GO:0008273///calcium, potassium:sodium antiporter activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity" GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006816///calcium ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0030282///bone mineralization+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0098656///anion transmembrane transport 94253 94253 'Hecw1' mRNA 73 89 76 0.33 0.43 0.36 0.04 0.03 0.03 0.373333333 0.033333333 10 5 6 79.33333333 7 6.12E-14 -3.515694145 GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048814///regulation of dendrite morphogenesis+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity 94254 94254 'Rcc1l' mRNA 590 593 362 13.24 13.23 7.81 6.29 11.46 9.74 11.42666667 9.163333333 336 568 495 515 466.3333333 0.569255622 -0.139643618 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019843///rRNA binding GO:0050790///regulation of catalytic activity+++GO:0070131///positive regulation of mitochondrial translation+++GO:1990613///mitochondrial membrane fusion 94275 94275 'Maged1' mRNA 6716 7302 6985 137.55 147.2 151.75 177.02 180.09 174.33 145.5 177.1466667 9943 9879 9481 7001 9767.666667 1.20E-15 0.468086352 04722///Neurotrophin signaling pathway GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032922///circadian regulation of gene expression+++GO:0042752///regulation of circadian rhythm+++GO:0042981///regulation of apoptotic process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:1900181///negative regulation of protein localization to nucleus+++GO:2001235///positive regulation of apoptotic signaling pathway" 94279 94279 'Sfxn2' mRNA 481.41 383.15 466.79 8.19 6.42 8.43 7.6 8.48 8.22 7.68 8.1 514.15 559.98 538.01 443.7833333 537.38 0.075555007 0.262568819 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0015075///ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0022889///serine transmembrane transporter activity GO:0006811///ion transport+++GO:0006865///amino acid transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990542///mitochondrial transmembrane transport 94280 94280 'Sfxn3' mRNA 2408 2468 2047 43.57 43.61 39.01 32.86 35.85 35.4 42.06333333 34.70333333 2056 2187 2150 2307.666667 2131 0.139639473 -0.122628416 GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0015075///ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0022889///serine transmembrane transporter activity GO:0006730///one-carbon metabolic process+++GO:0006811///ion transport+++GO:0006865///amino acid transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990542///mitochondrial transmembrane transport 94281 94281 'Sfxn4' mRNA 495.15 472.83 542 9.54 8.82 10.94 4.91 5.23 5.21 9.766666667 5.116666667 290.36 303.17 299.13 503.3266667 297.5533333 2.51E-08 -0.773325636 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane GO:0015075///ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006865///amino acid transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990542///mitochondrial transmembrane transport 94282 94282 'Sfxn5' mRNA 4678 4016 4715 70.64 59.36 75.31 37.23 37.15 38.42 68.43666667 37.6 2862 2761 2836 4469.666667 2819.666667 1.90E-16 -0.680213517 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane GO:0015075///ion transmembrane transporter activity+++GO:0015137///citrate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity GO:0006811///ion transport+++GO:0006865///amino acid transport+++GO:0015746///citrate transport+++GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:1990542///mitochondrial transmembrane transport 94284 94284 'Ugt1a6a' mRNA 80.46 66.42 73.06 1.33 1.08 1.28 1.32 1.28 1.72 1.23 1.44 91.86 86.78 116.18 73.31333333 98.27333333 0.18489782 0.40745695 00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++00140///Steroid hormone biosynthesis+++00830///Retinol metabolism+++00860///Porphyrin metabolism+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++01240///Biosynthesis of cofactors+++04976///Bile secretion+++05204///Chemical carcinogenesis - DNA adducts+++05207///Chemical carcinogenesis - receptor activation GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0004857///enzyme inhibitor activity+++GO:0005080///protein kinase C binding+++GO:0005496///steroid binding+++GO:0005504///fatty acid binding+++GO:0008144///drug binding+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0046982///protein heterodimerization activity" GO:0006711///estrogen catabolic process+++GO:0008210///estrogen metabolic process+++GO:0019439///aromatic compound catabolic process+++GO:0019585///glucuronate metabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0046226///coumarin catabolic process+++GO:0052695///cellular glucuronidation+++GO:0052696///flavonoid glucuronidation+++GO:0052697///xenobiotic glucuronidation 94315 94315 'Prcc' mRNA 96 92 52 2.65 2.51 1.53 2.02 1.6 1.94 2.23 1.853333333 84 65 78 80 75.66666667 0.854677737 -0.083381867 05202///Transcriptional misregulation in cancer+++05211///Renal cell carcinoma GO:0005634///nucleus+++GO:0016607///nuclear speck GO:0003674///molecular_function GO:0051726///regulation of cell cycle 94332 94332 'Cadm3' mRNA 190.37 195.88 178.05 2.1 2.08 1.87 1.13 0.76 0.85 2.016666667 0.913333333 125.45 84.36 96.36 188.1 102.0566667 3.98E-05 -0.897967996 04514///Cell adhesion molecules GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0099056///integral component of presynaptic membrane GO:0005515///protein binding+++GO:0042803///protein homodimerization activity GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0008104///protein localization 94346 94346 'Tmem40' mRNA 75 99 86 3.71 4.88 4.42 2.47 3.94 2.86 4.336666667 3.09 63 96 68 86.66666667 75.66666667 0.584637741 -0.203947953 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 94352 94352 'Loxl2' mRNA 86.66 62.66 95.82 0.83 0.59 0.97 4.65 4.84 4.95 0.796666667 4.813333333 538.19 556.22 560.06 81.71333333 551.49 1.50E-56 2.751307227 GO:0000785///chromatin+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix "GO:0004720///protein-lysine 6-oxidase activity+++GO:0005044///scavenger receptor activity+++GO:0005507///copper ion binding+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0016641///oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor+++GO:0046872///metal ion binding+++GO:0070492///oligosaccharide binding" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia+++GO:0001837///epithelial to mesenchymal transition+++GO:0001935///endothelial cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0006325///chromatin organization+++GO:0006464///cellular protein modification process+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0018057///peptidyl-lysine oxidation+++GO:0030199///collagen fibril organization+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0043542///endothelial cell migration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046688///response to copper ion+++GO:0070828///heterochromatin organization+++GO:1902455///negative regulation of stem cell population maintenance" 94353 94353 'Hmgn3' mRNA 1726 1760 1831 94.65 92.67 105.7 75.19 76.25 74.85 97.67333333 75.43 1501 1497 1438 1772.333333 1478.666667 0.001161345 -0.275041283 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus 96875 96875 'Prg4' mRNA 37.28 29.53 25.25 0.59 0.7 0.48 4.02 3.68 3.62 0.59 3.773333333 282.51 243.18 258.86 30.68666667 261.5166667 1.04E-37 3.094850985 GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix GO:0005044///scavenger receptor activity+++GO:0030247///polysaccharide binding GO:0006897///endocytosis+++GO:0006955///immune response+++GO:0032715///negative regulation of interleukin-6 production+++GO:0042127///regulation of cell proliferation+++GO:0071425///hematopoietic stem cell proliferation 96935 96935 'Susd4' mRNA 326 369 406 5.84 6.55 7.69 4 3.77 4.51 6.693333333 4.093333333 257 237 278 367 257.3333333 0.001315924 -0.528179872 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function "GO:0030449///regulation of complement activation+++GO:0045957///negative regulation of complement activation, alternative pathway+++GO:0045959///negative regulation of complement activation, classical pathway" 96957 96957 'Tmem62' mRNA 452 499 416 9.18 10.35 9.03 5.74 6.02 5.55 9.52 5.77 329 325 301 455.6666667 318.3333333 7.24E-05 -0.526884214 GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0016787///hydrolase activity GO:0008150///biological_process 96979 96979 'Ptges2' mRNA 403 429 138 11.79 12.36 4.28 3.89 6.33 5.7 9.476666667 5.306666667 153 243 217 323.3333333 204.3333333 0.27838349 -0.646598737 00590///Arachidonic acid metabolism GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0005795///Golgi stack+++GO:0005801///cis-Golgi network+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031252///cell leading edge "GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016829///lyase activity+++GO:0016853///isomerase activity+++GO:0020037///heme binding+++GO:0036134///12-hydroxyheptadecatrienoic acid synthase activity+++GO:0043295///glutathione binding+++GO:0050220///prostaglandin-E synthase activity+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding" "GO:0001516///prostaglandin biosynthetic process+++GO:0002263///cell activation involved in immune response+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006693///prostaglandin metabolic process+++GO:0006749///glutathione metabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006895///Golgi to endosome transport+++GO:0007030///Golgi organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0030593///neutrophil chemotaxis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0034067///protein localization to Golgi apparatus+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046903///secretion+++GO:0048205///COPI coating of Golgi vesicle+++GO:0050790///regulation of catalytic activity+++GO:0061162///establishment of monopolar cell polarity+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0090166///Golgi disassembly+++GO:0097111///endoplasmic reticulum-Golgi intermediate compartment organization+++GO:0098586///cellular response to virus+++GO:1903409///reactive oxygen species biosynthetic process+++GO:1903420///protein localization to endoplasmic reticulum tubular network+++GO:2000008///regulation of protein localization to cell surface" 97031 97031 'Tprn' mRNA 407 404 394 8 7.82 8.22 9.52 8.59 9.05 8.013333333 9.053333333 557 491 513 401.6666667 520.3333333 0.003762311 0.360744359 GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0042995///cell projection+++GO:0120044///stereocilium base GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019902///phosphatase binding GO:0007605///sensory perception of sound+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0120045///stereocilium maintenance 97064 97064 'Wwtr1' mRNA 932 903 778 10.51 10.01 9.3 17.64 17.06 18 9.94 17.56666667 1801 1702 1780 871 1761 1.55E-36 1.006221223 04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016604///nuclear body+++GO:0031966///mitochondrial membrane "GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008374///O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042803///protein homodimerization activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity" "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000423///mitophagy+++GO:0001649///osteoblast differentiation+++GO:0001894///tissue homeostasis+++GO:0001933///negative regulation of protein phosphorylation+++GO:0003007///heart morphogenesis+++GO:0003015///heart process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0006644///phospholipid metabolic process+++GO:0006936///muscle contraction+++GO:0007005///mitochondrion organization+++GO:0007007///inner mitochondrial membrane organization+++GO:0007507///heart development+++GO:0007519///skeletal muscle tissue development+++GO:0008284///positive regulation of cell proliferation+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0016567///protein ubiquitination+++GO:0017145///stem cell division+++GO:0030097///hemopoiesis+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0032048///cardiolipin metabolic process+++GO:0032049///cardiolipin biosynthetic process+++GO:0032835///glomerulus development+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0035264///multicellular organism growth+++GO:0035329///hippo signaling+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0042407///cristae formation+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0045599///negative regulation of fat cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046471///phosphatidylglycerol metabolic process+++GO:0048137///spermatocyte division+++GO:0048738///cardiac muscle tissue development+++GO:0048762///mesenchymal cell differentiation+++GO:0060048///cardiac muscle contraction+++GO:0060271///cilium assembly+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0060993///kidney morphogenesis+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:1900182///positive regulation of protein localization to nucleus+++GO:1900210///positive regulation of cardiolipin metabolic process+++GO:2001171///positive regulation of ATP biosynthetic process" 97086 97086 'Slc9b2' mRNA 304.31 326.45 257.65 4 4.2 3.72 2 2 2.02 3.973333333 2.006666667 196.72 176.67 172.3 296.1366667 181.8966667 1.68E-05 -0.714129023 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031514///motile cilium+++GO:0031966///mitochondrial membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0097228///sperm principal piece+++GO:0097708///intracellular vesicle GO:0010348///lithium:proton antiporter activity+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0042802///identical protein binding GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:0030001///metal ion transport+++GO:0030317///flagellated sperm motility+++GO:0035725///sodium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0072583///clathrin-dependent endocytosis+++GO:1902600///proton transmembrane transport+++GO:2001206///positive regulation of osteoclast development 97112 97112 'Nmd3' mRNA 669 797 737 22.29 26.17 26.1 25.79 26.64 27.3 24.85333333 26.57666667 890 893 907 734.3333333 896.6666667 0.010570936 0.276279491 03008///Ribosome biogenesis in eukaryotes+++03013///Nucleocytoplasmic transport GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0030674///protein binding, bridging+++GO:0043023///ribosomal large subunit binding" GO:0000055///ribosomal large subunit export from nucleus+++GO:0015031///protein transport+++GO:0032092///positive regulation of protein binding+++GO:1902680///positive regulation of RNA biosynthetic process+++GO:1904751///positive regulation of protein localization to nucleolus 97114 97114 'H3c15' mRNA 8.57 10.86 6 0.97 1.23 0.72 2.52 2.7 3.89 0.973333333 3.036666667 25.34 26.39 37.69 8.476666667 29.80666667 0.002469042 1.869992559 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 97122 97122 'H4c14' mRNA 19 18 16 5.19 4.97 4.65 4.61 3.01 3.03 4.936666667 3.55 19 12 12 17.66666667 14.33333333 0.6953238 -0.315148123 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity "GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0006352///DNA-templated transcription, initiation+++GO:0045653///negative regulation of megakaryocyte differentiation" 97130 97130 'C77080' mRNA 1719 1726 1566 18.15 17.9 17.55 9.04 9.04 9.44 17.86666667 9.173333333 975 964 995 1670.333333 978 1.79E-24 -0.78252619 GO:0005575///cellular_component GO:0003674///molecular_function GO:0030154///cell differentiation 97159 97159 'A430005L14Rik' mRNA 494 511 499 28.15 28.91 30.17 33.82 41.12 33.83 29.07666667 36.25666667 673 805 657 501.3333333 711.6666667 6.86E-05 0.49476133 GO:0005634///nucleus+++GO:0005654///nucleoplasm GO:0003674///molecular_function GO:0008150///biological_process 97165 97165 'Hmgb2' mRNA 552 494 514 11.36 10 11.22 30.33 32.34 32.53 10.86 31.73333333 1696 1766 1761 520 1741 1.78E-82 1.731749125 GO:0000785///chromatin+++GO:0000793///condensed chromosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm "GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0008301///DNA binding, bending+++GO:0019904///protein domain specific binding+++GO:0042056///chemoattractant activity+++GO:0044378///non-sequence-specific DNA binding, bending+++GO:0050786///RAGE receptor binding+++GO:0097100///supercoiled DNA binding" "GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002376///immune system process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0006265///DNA topological change+++GO:0006310///DNA recombination+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006935///chemotaxis+++GO:0006954///inflammatory response+++GO:0007283///spermatogenesis+++GO:0007289///spermatid nucleus differentiation+++GO:0008584///male gonad development+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:0032075///positive regulation of nuclease activity+++GO:0032496///response to lipopolysaccharide+++GO:0032728///positive regulation of interferon-beta production+++GO:0043388///positive regulation of DNA binding+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048545///response to steroid hormone+++GO:0050767///regulation of neurogenesis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0050918///positive chemotaxis+++GO:0060326///cell chemotaxis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0072091///regulation of stem cell proliferation+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors" 97212 97212 'Hadha' mRNA 2356 2460 2282 48 49.34 49.32 62.29 58.29 61.15 48.88666667 60.57666667 3517 3214 3343 2366 3358 1.61E-15 0.493308901 "00062///Fatty acid elongation+++00071///Fatty acid degradation+++00280///Valine, leucine and isoleucine degradation+++00310///Lysine degradation+++00380///Tryptophan metabolism+++00410///beta-Alanine metabolism+++00640///Propanoate metabolism+++00650///Butanoate metabolism+++01212///Fatty acid metabolism" GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016507///mitochondrial fatty acid beta-oxidation multienzyme complex+++GO:0042645///mitochondrial nucleoid "GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0003857///3-hydroxyacyl-CoA dehydrogenase activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016508///long-chain-enoyl-CoA hydratase activity+++GO:0016509///long-chain-3-hydroxyacyl-CoA dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016740///transferase activity+++GO:0016829///lyase activity+++GO:0044877///protein-containing complex binding+++GO:0051287///NAD binding+++GO:0070403///NAD+ binding" GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006635///fatty acid beta-oxidation+++GO:0008152///metabolic process+++GO:0009410///response to xenobiotic stimulus+++GO:0032868///response to insulin+++GO:0035965///cardiolipin acyl-chain remodeling+++GO:0042493///response to drug 97243 97243 'Naa11' mRNA 4 5 6 0.06 0.08 0.1 0.08 0.14 0.07 0.08 0.096666667 6 10 5 5 7 0.723375404 0.47183936 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031415///NatA complex "GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:1990189///peptide-serine-N-acetyltransferase activity+++GO:1990190///peptide-glutamate-N-acetyltransferase activity" GO:0006474///N-terminal protein amino acid acetylation+++GO:0017198///N-terminal peptidyl-serine acetylation+++GO:0018002///N-terminal peptidyl-glutamic acid acetylation 97287 97287 'Mtmr14' mRNA 658 682 642 14.63 14.81 15.4 13.46 12.56 12 14.94666667 12.67333333 691 636 607 660.6666667 644.6666667 0.742730112 -0.047502934 00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04140///Autophagy - animal GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation 97387 97387 'Strn4' mRNA 1116 1141 647 17.2 17.35 10.66 9.09 8.3 10.08 15.07 9.156666667 669 594 723 968 662 4.66E-04 -0.548680188 04013///MAPK signaling pathway - fly GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0090443///FAR/SIN/STRIPAK complex GO:0005516///calmodulin binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0051721///protein phosphatase 2A binding+++GO:0070016///armadillo repeat domain binding GO:0008150///biological_process 97440 97440 'B3gnt9' mRNA 35.95 37.84 34.02 0.82 0.88 0.85 2.88 2.55 2.95 0.85 2.793333333 141.08 121.8 144.81 35.93666667 135.8966667 3.59E-12 1.925620489 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process 97484 97484 'Cog8' mRNA 669 700 671 18.01 18.56 19.16 17.39 17.05 17.7 18.57666667 17.38 743 711 732 680 728.6666667 0.473517203 0.087672235 GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0017119///Golgi transport complex GO:0003674///molecular_function GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0015031///protein transport 97487 97487 'Cmtm4' mRNA 704 720 631 4.79 4.82 4.56 2.45 2.18 2.24 4.723333333 2.29 414 361 367 685 380.6666667 2.21E-14 -0.858375096 GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 97541 97541 'Qars' mRNA 1038 1041 1008 23.12 22.83 23.82 29.01 26.42 25.93 23.25666667 27.12 1498 1332 1296 1029 1375.333333 2.83E-06 0.405685815 00970///Aminoacyl-tRNA biosynthesis GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0032991///protein-containing complex GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004819///glutamine-tRNA ligase activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0019901///protein kinase binding "GO:0006412///translation+++GO:0006418///tRNA aminoacylation for protein translation+++GO:0006425///glutaminyl-tRNA aminoacylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007420///brain development+++GO:0032873///negative regulation of stress-activated MAPK cascade+++GO:0043039///tRNA aminoacylation+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2001234///negative regulation of apoptotic signaling pathway" 97761 97761 'Sgsm2' mRNA 480 484 450 5.75 5.69 5.87 3.26 2.83 3.04 5.77 3.043333333 330 274 291 471.3333333 298.3333333 3.38E-07 -0.672118995 GO:0005737///cytoplasm+++GO:0042470///melanosome GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding GO:0006886///intracellular protein transport+++GO:0034499///late endosome to Golgi transport+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity 97820 97820 '4833439L19Rik' mRNA 7557 7814.01 7979.21 160.36 162.82 178.73 112.58 118.22 109.97 167.3033333 113.59 6123.87 6244.6 5798.6 7783.406667 6055.69 1.27E-08 -0.375701173 GO:0005737///cytoplasm GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity GO:0008150///biological_process 97827 97827 'Exd2' mRNA 892 762 767 14.67 12.37 13.36 7.07 7.92 7.1 13.46666667 7.363333333 492 542 480 807 504.6666667 1.84E-09 -0.687793942 GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0090734///site of DNA damage GO:0000175///3'-5'-exoribonuclease activity+++GO:0000287///magnesium ion binding+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0008852///exodeoxyribonuclease I activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding "GO:0000724///double-strand break repair via homologous recombination+++GO:0000729///DNA double-strand break processing+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006281///DNA repair+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic" 97848 97848 'Serpinb6c' mRNA 4 0 4 0.18 0 0.21 0 0.04 0.05 0.13 0.03 0 1 1 2.666666667 0.666666667 0.422644949 -2.024284309 05146///Amoebiasis GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0097180///serine protease inhibitor complex GO:0002020///protease binding+++GO:0004867///serine-type endopeptidase inhibitor activity GO:0007605///sensory perception of sound+++GO:0010951///negative regulation of endopeptidase activity+++GO:0071470///cellular response to osmotic stress 97863 97863 'Fam8a1' mRNA 313 263 263 4.61 3.84 4.19 4.12 3.19 4.14 4.213333333 3.816666667 321 242 308 279.6666667 290.3333333 0.863090843 0.041078267 GO:0000836///Hrd1p ubiquitin ligase complex+++GO:0000839///Hrd1p ubiquitin ligase ERAD-L complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0008150///biological_process 97884 97884 'B3galnt2' mRNA 624.82 640.6 653 9.09 9.16 10.36 8.69 8.62 8.23 9.536666667 8.513333333 680.24 622.19 631.24 639.4733333 644.5566667 0.997552379 -0.001737703 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0008194///UDP-glycosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016758///transferase activity, transferring hexosyl groups" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0019276///UDP-N-acetylgalactosamine metabolic process 97895 97895 'Nlrp4f' mRNA 0 0 1 0 0 0.02 0 0.04 0 0.006666667 0.013333333 0 3 0 0.333333333 1 0.748070175 1.492165723 05130///Pathogenic Escherichia coli infection GO:0005737///cytoplasm+++GO:0005938///cell cortex GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding GO:0001701///in utero embryonic development+++GO:0006954///inflammatory response+++GO:0007015///actin filament organization+++GO:0040019///positive regulation of embryonic development+++GO:0051656///establishment of organelle localization 97908 97908 'H3c8' mRNA 0 1 0 0 0.17 0 0.31 0 0.95 0.056666667 0.42 2 0 6 0.333333333 2.666666667 0.295980186 2.8817729 04613///Neutrophil extracellular trap formation+++05034///Alcoholism+++05131///Shigellosis+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus GO:0000228///nuclear chromosome+++GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0060968///regulation of gene silencing 97961 97961 'Nol12' mRNA 466 448 406 23.61 21.95 21.11 29.06 30.78 29.96 22.22333333 29.93333333 629 652 635 440 638.6666667 3.10E-06 0.527898135 GO:0005634///nucleus+++GO:0005730///nucleolus GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding+++GO:0019843///rRNA binding+++GO:0042802///identical protein binding 97998 97998 'Deptor' mRNA 2968.83 3074 2628 18.24 18.56 17.13 16.26 14.94 15.2 17.97666667 15.46666667 3048 2736 2761 2890.276667 2848.333333 0.73338631 -0.031115261 04140///Autophagy - animal+++04150///mTOR signaling pathway GO:0006469///negative regulation of protein kinase activity+++GO:0032007///negative regulation of TOR signaling+++GO:0035556///intracellular signal transduction+++GO:0045792///negative regulation of cell size+++GO:1903940///negative regulation of TORC2 signaling+++GO:1904262///negative regulation of TORC1 signaling+++GO:2001236///regulation of extrinsic apoptotic signaling pathway 98053 98053 'Gtf2f1' mRNA 1176 1225 1251 39.21 40.29 44.29 45.66 48.99 45.79 41.26333333 46.81333333 1575 1656 1527 1217.333333 1586 2.98E-05 0.368805516 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005674///transcription factor TFIIF complex+++GO:0030054///cell junction+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle GO:0001096///TFIIF-class transcription factor complex binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0019211///phosphatase activator activity+++GO:0019903///protein phosphatase binding+++GO:0019904///protein domain specific binding+++GO:1990841///promoter-specific chromatin binding GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0009615///response to virus+++GO:0032091///negative regulation of protein binding+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050790///regulation of catalytic activity 98170 98170 'Tmem132a' mRNA 995 988 907 15.51 15.15 15 16.08 15.1 14.88 15.22 15.35333333 1187 1089 1064 963.3333333 1113.333333 0.032067933 0.19749697 GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0030426///growth cone+++GO:0032991///protein-containing complex+++GO:0044853///plasma membrane raft+++GO:0045121///membrane raft GO:0003674///molecular_function+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0015279///store-operated calcium channel activity+++GO:0042802///identical protein binding GO:0002115///store-operated calcium entry+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0043069///negative regulation of programmed cell death+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:0051924///regulation of calcium ion transport+++GO:0051928///positive regulation of calcium ion transport+++GO:0061180///mammary gland epithelium development+++GO:0070509///calcium ion import+++GO:0070588///calcium ion transmembrane transport 98193 98193 'Dcaf8' mRNA 4778 5074 5128 67.96 72.05 78.75 54.54 55.1 53.26 72.92 54.3 4297 4239 4060 4993.333333 4198.666667 1.41E-04 -0.263720088 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 98221 98221 'Eif3m' mRNA 1966 2236 2040 97.7 109.72 107.56 117.03 127.5 124.61 104.9933333 123.0466667 2703 2872 2783 2080.666667 2786 5.10E-08 0.410377181 "GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m" GO:0003743///translation initiation factor activity+++GO:0031369///translation initiation factor binding GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation 98238 98238 'Lrrc59' mRNA 565.94 545.6 445.88 11.01 10.45 9.21 19.61 22.56 20.54 10.22333333 20.90333333 1159.02 1302.58 1175.81 519.14 1212.47 8.86E-32 1.218511882 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042645///mitochondrial nucleoid+++GO:0043231///intracellular membrane-bounded organelle 98256 98256 'Kmo' mRNA 17 21 24 0.38 0.46 0.57 0.89 1.43 1.26 0.47 1.193333333 46 72 63 20.66666667 60.33333333 2.69E-04 1.533913396 00380///Tryptophan metabolism+++01240///Biosynthesis of cofactors GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane GO:0004497///monooxygenase activity+++GO:0004502///kynurenine 3-monooxygenase activity+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding "GO:0006569///tryptophan catabolic process+++GO:0007568///aging+++GO:0009435///NAD biosynthetic process+++GO:0009651///response to salt stress+++GO:0014049///positive regulation of glutamate secretion+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0019674///NAD metabolic process+++GO:0019805///quinolinate biosynthetic process+++GO:0032496///response to lipopolysaccharide+++GO:0034276///kynurenic acid biosynthetic process+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0043420///anthranilate metabolic process+++GO:0070189///kynurenine metabolic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0097052///L-kynurenine metabolic process+++GO:1901216///positive regulation of neuron death+++GO:1903296///positive regulation of glutamate secretion, neurotransmission" 98258 98258 'Txndc9' mRNA 1094 1175 1116 41.1 42.35 45.85 47.83 55.41 47.82 43.1 50.35333333 1366 1488 1316 1128.333333 1390 0.001744804 0.289718524 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0030496///midbody GO:0000226///microtubule cytoskeleton organization+++GO:0006457///protein folding 98267 98267 'Stk17b' mRNA 346 299 291 5.83 5.02 5.2 18.79 18.51 19.3 5.35 18.86666667 1288 1233 1266 312 1262.333333 2.60E-87 2.005600987 GO:0005634///nucleus+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0012501///programmed cell death+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:2000271///positive regulation of fibroblast apoptotic process 98303 98303 'D630023F18Rik' mRNA 810 778 858 36.14 33.85 40.72 5.12 4.69 3.51 36.90333333 4.44 123 109 90 815.3333333 107.3333333 3.06E-89 -2.940989545 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 98314 98314 'D2hgdh' mRNA 635 719 694 9.72 10.89 11.62 7.68 7.42 8.2 10.74333333 7.766666667 581 540 594 682.6666667 571.6666667 0.022946406 -0.26901853 GO:0005739///mitochondrion GO:0003824///catalytic activity+++GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051990///(R)-2-hydroxyglutarate dehydrogenase activity+++GO:0071949///FAD binding GO:0006108///malate metabolic process+++GO:0010042///response to manganese ion+++GO:0010043///response to zinc ion+++GO:0032025///response to cobalt ion+++GO:0032026///response to magnesium ion+++GO:0044267///cellular protein metabolic process+++GO:0051592///response to calcium ion 98363 98363 'Efhd1' mRNA 888 889 849 27.31 26.94 27.7 17.5 14.69 14.85 27.31666667 15.68 654 536 537 875.3333333 575.6666667 5.85E-09 -0.61780693 GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0061891///calcium ion sensor activity GO:0031175///neuron projection development+++GO:1900069///regulation of cellular hyperosmotic salinity response 98365 98365 'Slamf9' mRNA 64 78 62 3.47 4.17 3.56 20.34 19.8 19.87 3.733333333 20.00333333 431 409 407 68 415.6666667 2.43E-49 2.601827533 GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0002273///plasmacytoid dendritic cell differentiation+++GO:0002373///plasmacytoid dendritic cell cytokine production+++GO:0002410///plasmacytoid dendritic cell chemotaxis+++GO:0032604///granulocyte macrophage colony-stimulating factor production+++GO:0032611///interleukin-1 beta production+++GO:0032640///tumor necrosis factor production+++GO:0035393///chemokine (C-X-C motif) ligand 9 production+++GO:0042110///T cell activation+++GO:0042742///defense response to bacterium 98366 98366 'Smap1' mRNA 656.26 615.5 403.75 15.48 14.28 9.93 12.68 14.57 13.83 13.23 13.69333333 620.42 701.7 660.2 558.5033333 660.7733333 0.132130533 0.241308726 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030276///clathrin binding+++GO:0046872///metal ion binding GO:0031532///actin cytoskeleton reorganization+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0050790///regulation of catalytic activity+++GO:2000369///regulation of clathrin-dependent endocytosis 98376 98376 'Gorab' mRNA 277 284 279 6.06 6.11 6.47 4.66 5.61 5.3 6.213333333 5.19 245 288 270 280 267.6666667 0.725064452 -0.075782588 04115///p53 signaling pathway GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol GO:0005515///protein binding GO:0031069///hair follicle morphogenesis+++GO:1901622///positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:1905515///non-motile cilium assembly 98386 98386 'Lbr' mRNA 1126 1215 1168 17.23 18.28 18.93 19.12 17.38 18.14 18.14666667 18.21333333 1439 1280 1322 1169.666667 1347 0.0357007 0.190507502 00100///Steroid biosynthesis GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0005643///nuclear pore+++GO:0005652///nuclear lamina+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane "GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0050613///delta14-sterol reductase activity+++GO:0051087///chaperone binding+++GO:0070087///chromo shadow domain binding+++GO:0070402///NADPH binding" GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0030223///neutrophil differentiation 98388 98388 'Chst10' mRNA 203 233 82 3.57 4.01 1.53 1.36 1.53 1.26 3.036666667 1.383333333 89 98 79 172.6666667 88.66666667 0.002543207 -0.953489054 00515///Mannose type O-glycan biosynthesis GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0008146///sulfotransferase activity+++GO:0016232///HNK-1 sulfotransferase activity+++GO:0016740///transferase activity GO:0005975///carbohydrate metabolic process+++GO:0007612///learning+++GO:0007616///long-term memory+++GO:0016051///carbohydrate biosynthetic process+++GO:0030166///proteoglycan biosynthetic process 98396 98396 'Slc41a1' mRNA 3248 3201 2911 37.71 36.43 35.73 33.91 35.5 34.2 36.62333333 34.53666667 3391 3472 3316 3120 3393 0.10401368 0.111061895 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0032991///protein-containing complex GO:0008324///cation transmembrane transporter activity+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0061768///magnesium:sodium antiporter activity GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0010961///cellular magnesium ion homeostasis+++GO:0015693///magnesium ion transport+++GO:0030001///metal ion transport+++GO:0035725///sodium ion transmembrane transport+++GO:0071286///cellular response to magnesium ion+++GO:1903830///magnesium ion transmembrane transport 98402 98402 'Sh3bp4' mRNA 1318 1434 1356 14.02 14.97 15.31 10.44 11.49 10.61 14.76666667 10.84666667 1128 1214 1110 1369.333333 1150.666667 0.004019279 -0.262300004 GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005905///clathrin-coated pit+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle GO:0005092///GDP-dissociation inhibitor activity+++GO:0031267///small GTPase binding+++GO:0042802///identical protein binding GO:0006897///endocytosis+++GO:0008285///negative regulation of cell proliferation+++GO:0010508///positive regulation of autophagy+++GO:0030308///negative regulation of cell growth+++GO:0032007///negative regulation of TOR signaling+++GO:0034260///negative regulation of GTPase activity+++GO:0050790///regulation of catalytic activity+++GO:0061462///protein localization to lysosome+++GO:0071230///cellular response to amino acid stimulus 98403 98403 'Zfp451' mRNA 795 800 613 10.07 9.11 7.72 6.19 5.27 6.4 8.966666667 5.953333333 586 509 537 736 544 1.52E-04 -0.443924903 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061665///SUMO ligase activity GO:0010468///regulation of gene expression+++GO:0016925///protein sumoylation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060633///negative regulation of transcription initiation from RNA polymerase II promoter+++GO:2000616///negative regulation of histone H3-K9 acetylation 98404 98404 'AI597479' mRNA 797 798 832 12.55 12.36 13.89 10.05 9.79 8.79 12.93333333 9.543333333 735 699 622 809 685.3333333 0.026630184 -0.253410046 GO:0005634///nucleus+++GO:0072669///tRNA-splicing ligase complex GO:0003674///molecular_function GO:0008150///biological_process+++GO:0048598///embryonic morphogenesis 98415 98415 'Nucks1' mRNA 1651.93 1636.01 1519 14.37 13.99 14.02 18.51 14.42 17.32 14.12666667 16.75 2449.32 1865 2221.1 1602.313333 2178.473333 1.46E-06 0.430309525 GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding GO:0000724///double-strand break repair via homologous recombination+++GO:0001678///cellular glucose homeostasis+++GO:0006275///regulation of DNA replication+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019046///release from viral latency+++GO:0031297///replication fork processing+++GO:0036297///interstrand cross-link repair+++GO:0042593///glucose homeostasis+++GO:0043923///positive regulation by host of viral transcription+++GO:0044829///positive regulation by host of viral genome replication+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0060382///regulation of DNA strand elongation+++GO:0071481///cellular response to X-ray+++GO:1990968///modulation by host of RNA binding by virus+++GO:1990969///modulation by host of viral RNA-binding transcription factor activity 98417 98417 'Cnih4' mRNA 1231 1156 1070 20.96 19.28 19.49 26.01 27.21 24.87 19.91 26.03 1779 1807 1652 1152.333333 1746 2.38E-13 0.589335042 GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle GO:0031730///CCR5 chemokine receptor binding GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport 98432 98432 'Phlpp1' mRNA 1115 1203 952 9.69 10.27 8.77 3.18 2.9 2.94 9.576666667 3.006666667 422 375 378 1090 391.6666667 2.75E-46 -1.485351346 04151///PI3K-Akt signaling pathway GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding GO:0001932///regulation of protein phosphorylation+++GO:0002667///regulation of T cell anergy+++GO:0006470///protein dephosphorylation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0009649///entrainment of circadian clock+++GO:0042981///regulation of apoptotic process+++GO:0043408///regulation of MAPK cascade+++GO:0046328///regulation of JNK cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0090037///positive regulation of protein kinase C signaling+++GO:0090038///negative regulation of protein kinase C signaling+++GO:1900744///regulation of p38MAPK cascade 98488 98488 'Gtf3c3' mRNA 591 594 651 6.64 6.56 7.76 6.02 5.69 5.67 6.986666667 5.793333333 617 570 563 612 583.3333333 0.5678623 -0.084435523 GO:0000127///transcription factor TFIIIC complex+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0031965///nuclear membrane GO:0006383///transcription by RNA polymerase III 98496 98496 'Pid1' mRNA 1730 1852 1740 36.05 37.9 38.33 52.84 54.75 53.69 37.42666667 53.76 2923 2959 2873 1774 2918.333333 1.03E-25 0.706720136 GO:0005737///cytoplasm GO:0005515///protein binding GO:0001933///negative regulation of protein phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0042127///regulation of cell proliferation+++GO:0044320///cellular response to leptin stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046325///negative regulation of glucose import+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0070346///positive regulation of fat cell proliferation+++GO:0070584///mitochondrion morphogenesis+++GO:0071345///cellular response to cytokine stimulus+++GO:0071354///cellular response to interleukin-6+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071398///cellular response to fatty acid+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:2001170///negative regulation of ATP biosynthetic process+++GO:2001171///positive regulation of ATP biosynthetic process 98558 98558 'Mael' mRNA 0 4 3 0 0.15 0.12 0 0 0.07 0.09 0.023333333 0 0 2 2.333333333 0.666666667 0.525219452 -1.81976534 GO:0000785///chromatin+++GO:0001741///XY body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030849///autosome+++GO:0033391///chromatoid body+++GO:0043186///P granule+++GO:0048471///perinuclear region of cytoplasm+++GO:0071547///piP-body GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007129///synapsis+++GO:0007140///male meiotic nuclear division+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0009566///fertilization+++GO:0010629///negative regulation of gene expression+++GO:0030154///cell differentiation+++GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0043046///DNA methylation involved in gamete generation+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0046620///regulation of organ growth+++GO:0051321///meiotic cell cycle+++GO:0060964///regulation of gene silencing by miRNA" 98582 98582 'Khdc1b' mRNA 1 1 1 0.03 0.02 0.03 0.02 0 0 0.026666667 0.006666667 1 0 0 1 0.333333333 0.703393499 -1.493333342 GO:0005737///cytoplasm GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process 98660 98660 'Atp1a2' mRNA 51108.94 51101.06 45678.98 434.97 427.54 412.36 410.96 368.92 396.58 424.9566667 392.1533333 55601 48770.09 51978 49296.32667 52116.36333 0.229385519 0.069249584 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes+++04911///Insulin secretion+++04918///Thyroid hormone synthesis+++04919///Thyroid hormone signaling pathway+++04925///Aldosterone synthesis and secretion+++04960///Aldosterone-regulated sodium reabsorption+++04961///Endocrine and other factor-regulated calcium reabsorption+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04971///Gastric acid secretion+++04972///Pancreatic secretion+++04973///Carbohydrate digestion and absorption+++04974///Protein digestion and absorption+++04976///Bile secretion+++04978///Mineral absorption GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005901///caveola+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0031090///organelle membrane+++GO:0042383///sarcolemma+++GO:0042995///cell projection+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0043197///dendritic spine+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0000166///nucleotide binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0005496///steroid binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008556///potassium-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0019829///cation-transporting ATPase activity+++GO:0030955///potassium ion binding+++GO:0031402///sodium ion binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0051087///chaperone binding+++GO:1990239///steroid hormone binding GO:0001504///neurotransmitter uptake+++GO:0001662///behavioral fear response+++GO:0002026///regulation of the force of heart contraction+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:0006937///regulation of muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0006942///regulation of striated muscle contraction+++GO:0008217///regulation of blood pressure+++GO:0008344///adult locomotory behavior+++GO:0008542///visual learning+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0010996///response to auditory stimulus+++GO:0019229///regulation of vasoconstriction+++GO:0021764///amygdala development+++GO:0021989///olfactory cortex development+++GO:0030007///cellular potassium ion homeostasis+++GO:0035094///response to nicotine+++GO:0035641///locomotory exploration behavior+++GO:0035725///sodium ion transmembrane transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0040011///locomotion+++GO:0045822///negative regulation of heart contraction+++GO:0045988///negative regulation of striated muscle contraction+++GO:0046034///ATP metabolic process+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0071260///cellular response to mechanical stimulus+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0071805///potassium ion transmembrane transport+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0098655///cation transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:1903170///negative regulation of calcium ion transmembrane transport+++GO:1903280///negative regulation of calcium:sodium antiporter activity+++GO:1903416///response to glycoside+++GO:1990573///potassium ion import across plasma membrane 98682 98682 'Mfsd6' mRNA 963 947 683 11.38 10.79 8.5 6.25 6.4 6.84 10.22333333 6.496666667 620 621 658 864.3333333 633 1.68E-04 -0.454262191 GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0032393///MHC class I receptor activity+++GO:0042288///MHC class I protein binding GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I 98685 98685 'Trmt1l' mRNA 931 962 848 19.51 20.28 19.02 16.11 17.03 14.9 19.60333333 16.01333333 866 904 795 913.6666667 855 0.351205794 -0.105432672 GO:0005634///nucleus GO:0000049///tRNA binding+++GO:0003723///RNA binding+++GO:0004809///tRNA (guanine-N2-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding GO:0002940///tRNA N2-guanine methylation+++GO:0007610///behavior+++GO:0008033///tRNA processing+++GO:0008344///adult locomotory behavior+++GO:0030488///tRNA methylation+++GO:0030534///adult behavior+++GO:0032259///methylation 98710 98710 'Rabif' mRNA 609 722 692 17.48 20.42 21.07 23.22 23.4 22.93 19.65666667 23.18333333 930 915 889 674.3333333 911.3333333 8.42E-05 0.421627312 GO:0005829///cytosol+++GO:0016020///membrane GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0006892///post-Golgi vesicle-mediated transport+++GO:0007264///small GTPase mediated signal transduction+++GO:0015031///protein transport+++GO:0050790///regulation of catalytic activity 98711 98711 'Rdh10' mRNA 1635 1891 853 40 45.56 22.14 9.68 19.74 16.41 35.9 15.27666667 455 906 747 1459.666667 702.6666667 0.025359233 -1.043012533 00830///Retinol metabolism GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle "GO:0004745///retinol dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0052650///NADP-retinol dehydrogenase activity" GO:0001656///metanephros development+++GO:0001701///in utero embryonic development+++GO:0002138///retinoic acid biosynthetic process+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0009887///animal organ morphogenesis+++GO:0014032///neural crest cell development+++GO:0031076///embryonic camera-type eye development+++GO:0035115///embryonic forelimb morphogenesis+++GO:0042572///retinol metabolic process+++GO:0042574///retinal metabolic process+++GO:0043583///ear development+++GO:0043584///nose development+++GO:0048568///embryonic organ development+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0060431///primary lung bud formation+++GO:0060449///bud elongation involved in lung branching+++GO:1900054///positive regulation of retinoic acid biosynthetic process 98732 98732 'Rab3gap2' mRNA 1130 1255 1080 8.52 9.3 8.65 9.88 9.23 9.04 8.823333333 9.383333333 1507 1376 1337 1155 1406.666667 0.001553463 0.273585477 GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0031267///small GTPase binding GO:0043087///regulation of GTPase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0097051///establishment of protein localization to endoplasmic reticulum membrane+++GO:1903061///positive regulation of protein lipidation+++GO:1903373///positive regulation of endoplasmic reticulum tubular network organization+++GO:2000786///positive regulation of autophagosome assembly 98733 98733 'Obsl1' mRNA 1248 1212 875 17.65 16.61 12.83 9.65 15.46 12.96 15.69666667 12.69 811 1228 1036 1111.666667 1025 0.509614441 -0.117712964 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:1990393///3M complex GO:0000226///microtubule cytoskeleton organization+++GO:0007030///Golgi organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007416///synapse assembly+++GO:0010842///retina layer formation+++GO:0034067///protein localization to Golgi apparatus+++GO:0050775///positive regulation of dendrite morphogenesis 98741 98741 'Kcnb2' mRNA 91 86 69 0.31 0.28 0.25 0.02 0 0.02 0.28 0.013333333 6 0 6 82 4 5.99E-15 -4.368151165 GO:0005886///plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0032809///neuronal cell body membrane+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0044325///ion channel binding+++GO:0046982///protein heterodimerization activity GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0071805///potassium ion transmembrane transport+++GO:0072659///protein localization to plasma membrane 98758 98758 'Hnrnpf' mRNA 5488.45 5762.91 4936.2 135.64 140.85 132.11 179.8 182.58 180.94 136.2 181.1066667 8276.93 8234.06 8069.22 5395.853333 8193.403333 4.50E-29 0.593408744 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0071013///catalytic step 2 spliceosome+++GO:1990904///ribonucleoprotein complex GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0008134///transcription factor binding+++GO:0017025///TBP-class protein binding GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing 98766 98766 'Ubac1' mRNA 541 578 396 16.73 17.63 12.84 13.91 14.27 12.31 15.73333333 13.49666667 531 524 448 505 501 0.929481192 -0.016650397 GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane GO:0003674///molecular_function GO:0008150///biological_process+++GO:0016567///protein ubiquitination 98828 98828 'Cdc123' mRNA 1851.58 1913.71 1736.81 62.58 63.82 63.27 54.41 53.35 53.44 63.22333333 53.73333333 1822.13 1795.29 1710.15 1834.033333 1775.856667 0.521781586 -0.056814892 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0007049///cell cycle+++GO:0051301///cell division 98845 98845 'Eps8l2' mRNA 3627 3692 3603 64.9 65.01 68.39 21.03 20.32 20.4 66.1 20.58333333 1352 1276 1270 3640.666667 1299.333333 7.04E-114 -1.499083816 GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0032426///stereocilium tip+++GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0042995///cell projection GO:0003779///actin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0051015///actin filament binding GO:0007266///Rho protein signal transduction+++GO:0007605///sensory perception of sound+++GO:0016601///Rac protein signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050790///regulation of catalytic activity+++GO:1900029///positive regulation of ruffle assembly 98870 98870 'AI182371' mRNA 14.36 15.22 20.12 0.89 0.78 1.33 0.86 0.64 1.19 1 0.896666667 17.69 13.79 21.73 16.56666667 17.73666667 0.965568268 0.037839887 GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function+++GO:0004866///endopeptidase inhibitor activity "GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0006956///complement activation+++GO:0006957///complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0008150///biological_process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0045087///innate immune response" 98878 98878 'Ehd4' mRNA 1513 1511 1463 24.34 23.94 24.97 57.82 57.01 56.54 24.41666667 57.12333333 4133 3980 3915 1495.666667 4009.333333 9.23E-113 1.410625843 04144///Endocytosis GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0046872///metal ion binding GO:0006897///endocytosis+++GO:0006907///pinocytosis+++GO:0016197///endosomal transport+++GO:0030100///regulation of endocytosis+++GO:0032456///endocytic recycling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0051260///protein homooligomerization+++GO:0060271///cilium assembly+++GO:0071363///cellular response to growth factor stimulus+++GO:0072659///protein localization to plasma membrane 98910 98910 'Usp6nl' mRNA 1367.03 1278.32 1317.33 10.86 10.03 10.88 7.72 6.93 6.52 10.59 7.056666667 1175.28 977.09 932.76 1320.893333 1028.376667 1.77E-04 -0.375989604 GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle GO:0005096///GTPase activator activity+++GO:0031267///small GTPase binding "GO:0006886///intracellular protein transport+++GO:0007030///Golgi organization+++GO:0019068///virion assembly+++GO:0035526///retrograde transport, plasma membrane to Golgi+++GO:0043547///positive regulation of GTPase activity+++GO:0048227///plasma membrane to endosome transport+++GO:0090630///activation of GTPase activity+++GO:1903358///regulation of Golgi organization" 98932 98932 'Myl9' mRNA 2459 2511 2320 142.17 143.48 142.5 153.85 172.02 162.24 142.7166667 162.7033333 3049 3327 3110 2430 3162 1.14E-07 0.369884692 04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04360///Axon guidance+++04510///Focal adhesion+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05131///Shigellosis+++05132///Salmonella infection GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0016459///myosin complex+++GO:0016460///myosin II complex+++GO:0030018///Z disc GO:0005509///calcium ion binding+++GO:0032036///myosin heavy chain binding+++GO:0046872///metal ion binding 98952 98952 'Fam102a' mRNA 4240 4558 3680 54.13 57.23 49.83 18.04 17.32 19.43 53.73 18.26333333 1627 1526 1697 4159.333333 1616.666667 1.93E-84 -1.371660133 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 98956 98956 'Nat10' mRNA 441 501 486 5.78 6.44 6.88 4.95 5.13 4.97 6.366666667 5.016666667 418 428 412 476 419.3333333 0.167135814 -0.195360422 03008///Ribosome biogenesis in eukaryotes GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005730///nucleolus+++GO:0030496///midbody "GO:0000049///tRNA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008080///N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0070182///DNA polymerase binding+++GO:1990883///rRNA cytidine N-acetyltransferase activity" GO:0000154///rRNA modification+++GO:0006364///rRNA processing+++GO:0006473///protein acetylation+++GO:0008033///tRNA processing+++GO:0010824///regulation of centrosome duplication+++GO:0016072///rRNA metabolic process+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0034470///ncRNA processing+++GO:0042274///ribosomal small subunit biogenesis+++GO:0045727///positive regulation of translation+++GO:0051391///tRNA acetylation+++GO:1904812///rRNA acetylation involved in maturation of SSU-rRNA 98970 98970 'Fibcd1' mRNA 131 108 91 1.43 1.17 1.08 0.06 0.06 0.07 1.226666667 0.063333333 6 6 7 110 6.333333333 3.50E-20 -4.125553663 GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0062023///collagen-containing extracellular matrix GO:0005102///signaling receptor binding+++GO:0008061///chitin binding+++GO:0046872///metal ion binding GO:0007155///cell adhesion 98985 98985 'Clp1' mRNA 483 490 490 15.01 15 16.15 15.49 17.09 17.37 15.38666667 16.65 573 617 622 487.6666667 604 0.014808287 0.296996104 03015///mRNA surveillance pathway GO:0000214///tRNA-intron endonuclease complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005849///mRNA cleavage factor complex GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0046404///ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity+++GO:0051731///polynucleotide 5'-hydroxyl-kinase activity+++GO:0051733///polydeoxyribonucleotide kinase activity+++GO:0051734///ATP-dependent polynucleotide kinase activity+++GO:0051736///ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity "GO:0006378///mRNA polyadenylation+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008033///tRNA processing+++GO:0016310///phosphorylation+++GO:0021695///cerebellar cortex development+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031124///mRNA 3'-end processing+++GO:0035087///siRNA loading onto RISC involved in RNA interference" 98999 98999 'Znfx1' mRNA 1378 1423 1382 12.31 13.11 13.37 19.31 19 19.06 12.93 19.12333333 2476 2329 2307 1394.333333 2370.666667 1.62E-26 0.753180325 GO:0005634///nucleus+++GO:0031380///nuclear RNA-directed RNA polymerase complex GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0031048///chromatin silencing by small RNA 99003 99003 'Qser1' mRNA 928 992 799 5.5 5.74 5.08 4.43 4.44 4.39 5.44 4.42 796 771 782 906.3333333 783 0.03161914 -0.219481477 GO:0005575///cellular_component GO:0003674///molecular_function GO:0008150///biological_process 99010 99010 'Lpcat4' mRNA 133 140 72 4 4.15 2.3 6.81 10.38 8.98 3.483333333 8.723333333 260 387 332 115 326.3333333 3.70E-11 1.508132379 00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane "GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047166///1-alkenylglycerophosphoethanolamine O-acyltransferase activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047192///1-alkylglycerophosphocholine O-acetyltransferase activity+++GO:0071617///lysophospholipid acyltransferase activity" GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling 99011 99011 'Pomt1' mRNA 510 571 449 9.75 10.57 9.06 8.12 7.84 7.83 9.793333333 7.93 488 447 454 510 463 0.288006876 -0.148328353 00514///Other types of O-glycan biosynthesis+++00515///Mannose type O-glycan biosynthesis GO:0001669///acrosomal vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum "GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups" GO:0006486///protein glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0030198///extracellular matrix organization+++GO:0035269///protein O-linked mannosylation+++GO:0097502///mannosylation+++GO:1904100///positive regulation of protein O-linked glycosylation 99031 99031 'Osbpl6' mRNA 5872 5850 5221 43.01 41.37 40.91 8.63 8.83 9.95 41.76333333 9.136666667 1369 1244 1384 5647.666667 1332.333333 2.55E-247 -2.094082155 GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0031965///nuclear membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097038///perinuclear endoplasmic reticulum GO:0008289///lipid binding+++GO:0015248///sterol transporter activity+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0032374///regulation of cholesterol transport 99035 99035 'Olah' mRNA 6 4 3 0.23 0.15 0.1 0.05 0.03 0.07 0.16 0.05 2 1 2 4.333333333 1.666666667 0.405139176 -1.38545034 00061///Fatty acid biosynthesis GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005829///cytosol GO:0004320///oleoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016295///myristoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016296///palmitoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016297///acyl-[acyl-carrier-protein] hydrolase activity+++GO:0016787///hydrolase activity+++GO:0047381///dodecanoyl-[acyl-carrier-protein] hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0008610///lipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0051792///medium-chain fatty acid biosynthetic process 99045 99045 'Mrps26' mRNA 775 699 701 52.01 46.41 49.92 63.65 64.17 62.05 49.44666667 63.29 1087 1068 1024 725 1059.666667 1.40E-08 0.535817907 GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome GO:0008150///biological_process 99100 99100 'Cep152' mRNA 287 264 244 2.64 2.39 2.38 1.18 1.18 1.17 2.47 1.176666667 148 144 142 265 144.6666667 3.71E-07 -0.883526039 GO:0000242///pericentriolar material+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0098536///deuterosome GO:0005515///protein binding+++GO:0019901///protein kinase binding GO:0007099///centriole replication+++GO:0030030///cell projection organization+++GO:0051298///centrosome duplication+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation 99138 99138 'Stard7' mRNA 1895.25 1894.47 1060 35.12 34.88 20.74 16.28 22.95 20.24 30.24666667 19.82333333 1015 1397 1221.96 1616.573333 1211.32 0.203388995 -0.411971252 GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion GO:0008289///lipid binding GO:0001773///myeloid dendritic cell activation+++GO:0006954///inflammatory response+++GO:0035745///T-helper 2 cell cytokine production+++GO:0042092///type 2 immune response+++GO:0061436///establishment of skin barrier 99151 99151 'Cercam' mRNA 213.62 226.34 229.11 4.35 4.7 4.95 7.23 7.41 6.42 4.666666667 7.02 411.62 409 354 223.0233333 391.54 1.05E-07 0.800385179 GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen GO:0042802///identical protein binding+++GO:0050211///procollagen galactosyltransferase activity GO:0007155///cell adhesion+++GO:0018215///protein phosphopantetheinylation 99152 99152 'Anapc2' mRNA 3273 3433 3361 59.57 61.48 64.89 52.39 54.45 50.21 61.98 52.35 3312 3362 3074 3355.666667 3249.333333 0.490310011 -0.058912222 04110///Cell cycle+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++04914///Progesterone-mediated oocyte maturation+++05166///Human T-cell leukemia virus 1 infection GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005881///cytoplasmic microtubule+++GO:0005884///actin filament+++GO:0015630///microtubule cytoskeleton+++GO:0016342///catenin complex+++GO:0030496///midbody+++GO:0030877///beta-catenin destruction complex+++GO:0031258///lamellipodium membrane+++GO:0031941///filamentous actin+++GO:0045171///intercellular bridge+++GO:0048471///perinuclear region of cytoplasm+++GO:0098794///postsynapse GO:0008013///beta-catenin binding+++GO:0008017///microtubule binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0045295///gamma-catenin binding GO:0000226///microtubule cytoskeleton organization+++GO:0001708///cell fate specification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007049///cell cycle+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0010629///negative regulation of gene expression+++GO:0016055///Wnt signaling pathway+++GO:0016477///cell migration+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0031915///positive regulation of synaptic plasticity+++GO:0045595///regulation of cell differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0045773///positive regulation of axon extension+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090129///positive regulation of synapse maturation+++GO:0090630///activation of GTPase activity 99167 99167 'Ssx2ip' mRNA 890 932 642 13.82 14.23 10.62 4.93 4.56 5.91 12.89 5.133333333 362 330 421 821.3333333 371 2.34E-17 -1.151175685 04520///Adherens junction GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0030054///cell junction+++GO:0031252///cell leading edge+++GO:0032991///protein-containing complex+++GO:0034451///centriolar satellite+++GO:0036064///ciliary basal body+++GO:0042995///cell projection GO:0005515///protein binding+++GO:0019904///protein domain specific binding GO:0007098///centrosome cycle+++GO:0007155///cell adhesion+++GO:0030030///cell projection organization+++GO:0035020///regulation of Rac protein signal transduction+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0060271///cilium assembly+++GO:2000145///regulation of cell motility 99237 99237 'Tm9sf4' mRNA 1467 1530 1483 20.06 20.68 21.47 24.57 23.43 23.33 20.73666667 23.77666667 2047 1910 1887 1493.333333 1948 7.87E-07 0.37076128 GO:0005768///endosome+++GO:0005769///early endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001666///response to hypoxia+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0051453///regulation of intracellular pH+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0072657///protein localization to membrane+++GO:2000010///positive regulation of protein localization to cell surface 99296 99296 'Hrh3' mRNA 5 5 8 0.11 0.11 0.2 0.04 0.02 0.06 0.14 0.04 2 1 3 6 2 0.254500756 -1.610077753 04080///Neuroactive ligand-receptor interaction GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0043005///neuron projection+++GO:0043209///myelin sheath+++GO:0045202///synapse GO:0004930///G protein-coupled receptor activity+++GO:0004969///histamine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0043176///amine binding+++GO:1901363///heterocyclic compound binding "GO:0001505///regulation of neurotransmitter levels+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007268///chemical synaptic transmission+++GO:0007612///learning+++GO:0007613///memory+++GO:0014050///negative regulation of glutamate secretion+++GO:0014053///negative regulation of gamma-aminobutyric acid secretion+++GO:0014061///regulation of norepinephrine secretion+++GO:0014063///negative regulation of serotonin secretion+++GO:0014070///response to organic cyclic compound+++GO:0042755///eating behavior+++GO:0042756///drinking behavior+++GO:0045776///negative regulation of blood pressure+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0050890///cognition+++GO:0098664///G protein-coupled serotonin receptor signaling pathway" 99311 99311 'Commd7' mRNA 1067.51 1038.63 1059.18 18.12 17.35 19.07 20.81 21.28 22.57 18.18 21.55333333 1408.73 1408.18 1479.78 1055.106667 1432.23 5.48E-07 0.428496106 GO:0031410///cytoplasmic vesicle GO:0051059///NF-kappaB binding "GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated" 99326 99326 'Garnl3' mRNA 64 72 45 0.94 1.04 0.71 0.68 0.79 0.92 0.896666667 0.796666667 53 61 66 60.33333333 60 0.987065834 -0.010670889 GO:0005737///cytoplasm GO:0005096///GTPase activator activity GO:0050790///regulation of catalytic activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity 99334 99334 'Zscan29' mRNA 431.49 417.74 446.97 6.3 6.02 7.01 7.75 6.67 7.14 6.443333333 7.186666667 628.87 518.31 533.08 432.0666667 560.0866667 0.00591172 0.360520461 GO:0005634///nucleus "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0006357///regulation of transcription by RNA polymerase II 99349 99349 'Dnajc24' mRNA 294 261 289 15.08 13.22 15.72 16.76 15.76 15.44 14.67333333 15.98666667 375 344 334 281.3333333 351 0.053466361 0.304958176 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton GO:0001671///ATPase activator activity+++GO:0008198///ferrous iron binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0032781///positive regulation of ATPase activity+++GO:0050790///regulation of catalytic activity 99371 99371 'Arfgef2' mRNA 699 675 590 4.18 3.96 3.74 4.08 4.04 4.55 3.96 4.223333333 786 760 849 654.6666667 798.3333333 0.01038238 0.276957792 04144///Endocytosis GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005879///axonemal microtubule+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0032279///asymmetric synapse+++GO:0032280///symmetric synapse+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0043231///intracellular membrane-bounded organelle+++GO:0045202///synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0055037///recycling endosome GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0050811///GABA receptor binding GO:0001881///receptor recycling+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport+++GO:0007032///endosome organization+++GO:0010256///endomembrane system organization+++GO:0015031///protein transport+++GO:0032012///regulation of ARF protein signal transduction+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction+++GO:0050790///regulation of catalytic activity 99375 99375 'Cul4a' mRNA 1886 2118 1828 27.44 30.35 28.23 19.69 19.47 22.2 28.67333333 20.45333333 1558 1503 1698 1944 1586.333333 2.22E-04 -0.303352101 03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++05170///Human immunodeficiency virus 1 infection GO:0019005///SCF ubiquitin ligase complex+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding GO:0001701///in utero embryonic development+++GO:0006281///DNA repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0016032///viral process+++GO:0016567///protein ubiquitination+++GO:0030097///hemopoiesis+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0035019///somatic stem cell population maintenance+++GO:0042254///ribosome biogenesis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0048511///rhythmic process+++GO:0051246///regulation of protein metabolic process+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:2000001///regulation of DNA damage checkpoint+++GO:2000819///regulation of nucleotide-excision repair 99377 99377 'Sall4' mRNA 59 38 34 0.64 0.42 0.48 1.26 1.29 1.31 0.513333333 1.286666667 114 100 105 43.66666667 106.3333333 3.24E-05 1.275668876 GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0043231///intracellular membrane-bounded organelle "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding" GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001701///in utero embryonic development+++GO:0001833///inner cell mass cell proliferation+++GO:0001843///neural tube closure+++GO:0003281///ventricular septum development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0009888///tissue development+++GO:0019827///stem cell population maintenance+++GO:0021915///neural tube development+++GO:0030326///embryonic limb morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II 99382 99382 'Abtb2' mRNA 721 804 770 8.48 9.3 9.61 8.16 6.84 7.32 9.13 7.44 798 654 694 765 715.3333333 0.391180595 -0.110895201 GO:0005575///cellular_component GO:0003674///molecular_function+++GO:0046982///protein heterodimerization activity GO:0008150///biological_process+++GO:0097237///cellular response to toxic substance 99412 99412 'Golga2' mRNA 1398 1504 1424 17.74 18.69 18.95 15.71 15.12 15.69 18.46 15.50666667 1431 1342 1380 1442 1384.333333 0.459815276 -0.071156413 GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0032580///Golgi cisterna membrane+++GO:0032991///protein-containing complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043025///neuronal cell body+++GO:0048471///perinuclear region of cytoplasm+++GO:0072686///mitotic spindle GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0061676///importin-alpha family protein binding GO:0006486///protein glycosylation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007020///microtubule nucleation+++GO:0007030///Golgi organization+++GO:0007049///cell cycle+++GO:0007098///centrosome cycle+++GO:0008356///asymmetric cell division+++GO:0010507///negative regulation of autophagy+++GO:0015031///protein transport+++GO:0032091///negative regulation of protein binding+++GO:0050772///positive regulation of axonogenesis+++GO:0051225///spindle assembly+++GO:0051289///protein homotetramerization+++GO:0051301///cell division+++GO:0051645///Golgi localization+++GO:0060050///positive regulation of protein glycosylation+++GO:0090161///Golgi ribbon formation+++GO:0090166///Golgi disassembly+++GO:0090306///spindle assembly involved in meiosis+++GO:0090307///mitotic spindle assembly 99439 99439 'Duox1' mRNA 1 8 3 0.01 0.09 0.03 0.07 0.02 0.03 0.043333333 0.04 8 2 3 4 4.333333333 0.953060814 0.103944208 04013///MAPK signaling pathway - fly+++04624///Toll and Imd signaling pathway+++04918///Thyroid hormone synthesis GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031252///cell leading edge+++GO:0043020///NADPH oxidase complex+++GO:0045177///apical part of cell GO:0004601///peroxidase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding GO:0006590///thyroid hormone generation+++GO:0006952///defense response+++GO:0006979///response to oxidative stress+++GO:0009566///fertilization+++GO:0009615///response to virus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030282///bone mineralization+++GO:0030878///thyroid gland development+++GO:0035264///multicellular organism growth+++GO:0042335///cuticle development+++GO:0042403///thyroid hormone metabolic process+++GO:0042445///hormone metabolic process+++GO:0042446///hormone biosynthetic process+++GO:0042554///superoxide anion generation+++GO:0048839///inner ear development+++GO:0048855///adenohypophysis morphogenesis+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0051591///response to cAMP+++GO:0072593///reactive oxygen species metabolic process+++GO:0090303///positive regulation of wound healing+++GO:0098869///cellular oxidant detoxification+++GO:2000147///positive regulation of cell motility 99470 99470 'Magi3' mRNA 369 402 403 2.96 3.18 3.43 1.94 2.02 1.91 3.19 1.956666667 278 284 265 391.3333333 275.6666667 3.67E-04 -0.518486399 04015///Rap1 signaling pathway GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0030054///cell junction GO:0000166///nucleotide binding+++GO:0005109///frizzled binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0060090///molecular adaptor activity GO:0007165///signal transduction+++GO:0043507///positive regulation of JUN kinase activity+++GO:0046328///regulation of JNK cascade 99480 99480 'Dnttip2' mRNA 972 1105 974 22.61 25.31 24.04 25.59 25.81 25.39 23.98666667 25.59666667 1265 1246 1215 1017 1242 0.001868704 0.277614082 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005730///nucleolus GO:0006396///RNA processing 99512 99512 'Wdr47' mRNA 790 747 750 10.17 9.44 10.28 6.42 5.77 6.38 9.963333333 6.19 572 506 550 762.3333333 542.6666667 2.25E-06 -0.503253294 GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule GO:0003674///molecular_function GO:0007275///multicellular organism development 99526 99526 'Usp53' mRNA 790 716 626 7.57 6.6 6.16 6.7 6.81 7.62 6.776666667 7.043333333 839 806 891 710.6666667 845.3333333 0.029305884 0.241502664 GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction "GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0101005///ubiquitinyl hydrolase activity+++GO:1990837///sequence-specific double-stranded DNA binding" GO:0001508///action potential+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006508///proteolysis+++GO:0006915///apoptotic process+++GO:0007605///sensory perception of sound+++GO:0010996///response to auditory stimulus+++GO:0016579///protein deubiquitination+++GO:0042481///regulation of odontogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051402///neuron apoptotic process+++GO:1902070///positive regulation of sphingolipid mediated signaling pathway 99543 99543 'Olfml3' mRNA 942 997 953 31.42 32.78 33.72 113.04 107.64 108.65 32.64 109.7766667 3895 3620 3623 964 3712.666667 7.48E-177 1.932996007 GO:0005576///extracellular region GO:0003674///molecular_function GO:0007275///multicellular organism development+++GO:0008150///biological_process 99586 99586 'Dpyd' mRNA 379 393 369 4.63 4.74 4.78 0.81 0.7 0.46 4.716666667 0.656666667 76 63 42 380.3333333 60.33333333 1.17E-40 -2.669441877 00240///Pyrimidine metabolism+++00410///beta-Alanine metabolism+++00770///Pantothenate and CoA biosynthesis+++00983///Drug metabolism - other enzymes GO:0005737///cytoplasm+++GO:0005829///cytosol "GO:0000166///nucleotide binding+++GO:0002058///uracil binding+++GO:0003824///catalytic activity+++GO:0004159///dihydrouracil dehydrogenase (NAD+) activity+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0017113///dihydropyrimidine dehydrogenase (NADP+) activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0050661///NADP binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0071949///FAD binding" GO:0006145///purine nucleobase catabolic process+++GO:0006208///pyrimidine nucleobase catabolic process+++GO:0006210///thymine catabolic process+++GO:0006212///uracil catabolic process+++GO:0006214///thymidine catabolic process+++GO:0006248///CMP catabolic process+++GO:0006249///dCMP catabolic process+++GO:0007584///response to nutrient+++GO:0007623///circadian rhythm+++GO:0009410///response to xenobiotic stimulus+++GO:0014070///response to organic cyclic compound+++GO:0019483///beta-alanine biosynthetic process+++GO:0019860///uracil metabolic process+++GO:0042493///response to drug+++GO:0046050///UMP catabolic process+++GO:0046074///dTMP catabolic process+++GO:0046079///dUMP catabolic process 99633 99633 'Adgrl2' mRNA 2724 2585 1744 24.68 22.95 16.88 11.58 12.31 13.55 21.50333333 12.48 1456 1540 1663 2351 1553 2.05E-07 -0.600168325 GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0030165///PDZ domain binding+++GO:0030246///carbohydrate binding GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0009617///response to bacterium+++GO:0050808///synapse organization+++GO:0051965///positive regulation of synapse assembly 99650 99650 '4933434E20Rik' mRNA 3178.8 3109.29 3325.56 98.32 95.06 109.48 81.15 84.48 87.68 100.9533333 84.43666667 3103.39 3140.92 3207.14 3204.55 3150.483333 0.702622628 -0.038359105 GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0001701///in utero embryonic development+++GO:0006909///phagocytosis 99662 99662 'Eps8l3' mRNA 94 90 82 2.08 1.96 1.92 1.45 1.32 1.49 1.986666667 1.42 75 67 75 88.66666667 72.33333333 0.330224762 -0.304486636 GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane GO:0003779///actin binding GO:0007266///Rho protein signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0042634///regulation of hair cycle+++GO:1900029///positive regulation of ruffle assembly 99681 99681 'Tchh' mRNA 98 104 116 0.89 0.93 1.12 1.34 1.21 1.14 0.98 1.23 169 149 139 106 152.3333333 0.032218163 0.507081784 "GO:0005509///calcium ion binding+++GO:0030674///protein binding, bridging+++GO:0046914///transition metal ion binding" GO:0045109///intermediate filament organization 99683 99683 'Sec24b' mRNA 1326 1413 1260 13.84 14.56 14.09 10.95 11.64 11.7 14.16333333 11.43 1199 1252 1241 1333 1230.666667 0.170548637 -0.125167879 04141///Protein processing in endoplasmic reticulum+++05130///Pathogenic Escherichia coli infection GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0070971///endoplasmic reticulum exit site GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding GO:0001843///neural tube closure+++GO:0002093///auditory receptor cell morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0021747///cochlear nucleus development+++GO:0035909///aorta morphogenesis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060425///lung morphogenesis+++GO:0060463///lung lobe morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0061156///pulmonary artery morphogenesis+++GO:0072359///circulatory system development+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090178///regulation of establishment of planar polarity involved in neural tube closure+++GO:1901301///regulation of cargo loading into COPII-coated vesicle 99696 99696 'Ankrd50' mRNA 417 461 441 3.11 3.12 3.38 2.66 2.13 2.15 3.203333333 2.313333333 412 359 337 439.6666667 369.3333333 0.066961438 -0.265018911 GO:0003674///molecular_function GO:0032456///endocytic recycling 99712 99712 'Cept1' mRNA 1304.28 1254.71 1246.11 29.99 28.67 33.88 40.21 43.6 39.14 30.84666667 40.98333333 1936.03 2057.62 1906.41 1268.366667 1966.686667 3.10E-15 0.621547819 00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane "GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0046872///metal ion binding+++GO:0047359///1-alkenyl-2-acylglycerol choline phosphotransferase activity" GO:0006629///lipid metabolic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006657///CDP-choline pathway+++GO:0008654///phospholipid biosynthetic process 99730 99730 'Taf13' mRNA 863 876 900 40.57 40.65 44.89 60.32 62.97 56.06 42.03666667 59.78333333 1473 1500 1324 879.6666667 1432.333333 6.49E-14 0.690237715 03022///Basal transcription factors GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0005730///nucleolus GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0017025///TBP-class protein binding+++GO:0046982///protein heterodimerization activity GO:0006366///transcription by RNA polymerase II 99738 99738 'Kcnc4' mRNA 19 28 11 0.26 0.41 0.14 0.24 0.07 0.13 0.27 0.146666667 26 6 17 19.33333333 16.33333333 0.782653307 -0.249629928 GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0031594///neuromuscular junction+++GO:0032590///dendrite membrane+++GO:0032809///neuronal cell body membrane+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0044305///calyx of Held+++GO:0098690///glycinergic synapse+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0099055///integral component of postsynaptic membrane+++GO:0099056///integral component of presynaptic membrane GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0099508///voltage-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:1905030///voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0046928///regulation of neurotransmitter secretion+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0071805///potassium ion transmembrane transport+++GO:0099505///regulation of presynaptic membrane potential+++GO:1904057///negative regulation of sensory perception of pain+++GO:1904456///negative regulation of neuronal action potential 99887 99887 'Tlcd4' mRNA 473 480 433 4.01 4.23 3.89 1.96 1.86 2.17 4.043333333 1.996666667 271 245 288 462 268 2.90E-09 -0.796412799 GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane GO:0003674///molecular_function GO:0055088///lipid homeostasis 99889 99889 'Arfip1' mRNA 1146 1245 1139 21.05 22.5 22.27 26.36 25.82 24.56 21.94 25.58 1654 1578 1494 1176.666667 1575.333333 4.30E-07 0.409365056 GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane GO:0005543///phospholipid binding+++GO:0019904///protein domain specific binding+++GO:0070273///phosphatidylinositol-4-phosphate binding "GO:0006886///intracellular protein transport+++GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation+++GO:0050708///regulation of protein secretion+++GO:1905280///negative regulation of retrograde transport, endosome to Golgi" 99890 99890 'Prmt6' mRNA 188 229 112 4.24 5.08 2.68 2 3.35 2.25 4 2.533333333 102 167 111 176.3333333 126.6666667 0.110705735 -0.471834993 GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0035241///protein-arginine omega-N monomethyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0042054///histone methyltransferase activity+++GO:0042393///histone binding+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0070611///histone methyltransferase activity (H3-R2 specific)+++GO:0070612///histone methyltransferase activity (H2A-R3 specific) "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010821///regulation of mitochondrion organization+++GO:0016571///histone methylation+++GO:0018216///peptidyl-arginine methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0031064///negative regulation of histone deacetylation+++GO:0032259///methylation+++GO:0034970///histone H3-R2 methylation+++GO:0035246///peptidyl-arginine N-methylation+++GO:0043985///histone H4-R3 methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0090398///cellular senescence+++GO:1901796///regulation of signal transduction by p53 class mediator" 99899 99899 'Ifi44' mRNA 242 224 248 4.73 4.32 5.14 18.28 16.3 17.87 4.73 17.48333333 1069 939 1013 238 1007 1.38E-72 2.066840999 GO:0005737///cytoplasm GO:0003674///molecular_function GO:0006955///immune response+++GO:0009617///response to bacterium 99929 99929 'Tiparp' mRNA 1660 1689 1694 21.53 21.55 23.31 21.08 21.2 21.99 22.13 21.42333333 1871 1838 1890 1681 1866.333333 0.093973354 0.138175847 GO:0005634///nucleus "GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:1990404///protein ADP-ribosylase activity" "GO:0001570///vasculogenesis+++GO:0001822///kidney development+++GO:0006471///protein ADP-ribosylation+++GO:0006807///nitrogen compound metabolic process+++GO:0008152///metabolic process+++GO:0008209///androgen metabolic process+++GO:0008210///estrogen metabolic process+++GO:0008585///female gonad development+++GO:0009791///post-embryonic development+++GO:0010629///negative regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0045732///positive regulation of protein catabolic process+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0048705///skeletal system morphogenesis+++GO:0048745///smooth muscle tissue development+++GO:0060021///roof of mouth development+++GO:0060325///face morphogenesis+++GO:0070213///protein auto-ADP-ribosylation+++GO:0071407///cellular response to organic cyclic compound+++GO:1904612///response to 2,3,7,8-tetrachlorodibenzodioxine" 99982 99982 'Kdm1a' mRNA 425.07 432.68 475.65 7.63 7.64 9.05 8.17 7.37 7.76 8.106666667 7.766666667 521.61 456.73 480.12 444.4666667 486.1533333 0.469806757 0.113749183 04714///Thermogenesis "GO:0000781///chromosome, telomeric region+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:1990391///DNA repair complex" GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0002039///p53 binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0016491///oxidoreductase activity+++GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0032451///demethylase activity+++GO:0032452///histone demethylase activity+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0034648///histone demethylase activity (H3-dimethyl-K4 specific)+++GO:0034649///histone demethylase activity (H3-monomethyl-K4 specific)+++GO:0043426///MRF binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050681///androgen receptor binding+++GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0061752///telomeric repeat-containing RNA binding+++GO:1990841///promoter-specific chromatin binding "GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0006325///chromatin organization+++GO:0006342///chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006482///protein demethylation+++GO:0007275///multicellular organism development+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0010725///regulation of primitive erythrocyte differentiation+++GO:0010976///positive regulation of neuron projection development+++GO:0014070///response to organic cyclic compound+++GO:0021983///pituitary gland development+++GO:0021987///cerebral cortex development+++GO:0030154///cell differentiation+++GO:0030851///granulocyte differentiation+++GO:0031507///heterochromatin assembly+++GO:0032091///negative regulation of protein binding+++GO:0032880///regulation of protein localization+++GO:0033169///histone H3-K9 demethylation+++GO:0033184///positive regulation of histone ubiquitination+++GO:0034644///cellular response to UV+++GO:0034720///histone H3-K4 demethylation+++GO:0035563///positive regulation of chromatin binding+++GO:0042551///neuron maturation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0045793///positive regulation of cell size+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0046098///guanine metabolic process+++GO:0050767///regulation of neurogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0051573///negative regulation of histone H3-K9 methylation+++GO:0055001///muscle cell development+++GO:0060992///response to fungicide+++GO:0071320///cellular response to cAMP+++GO:0071480///cellular response to gamma radiation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1903827///regulation of cellular protein localization+++GO:1990138///neuron projection extension+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:2000648///positive regulation of stem cell proliferation"